tbuckley/cabot-search huggingface dataset:
UNSUSPECTED TRAUMA
Journal: JAMA (1961)

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US Physicians Share Nobel
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Contents
Authors: S Yazumi, S Singla, T Baron, I Rodrı ´guez-Lago, C Carretero, M Munoz-Navas, F Gleeson, C Brown, L Herrera Hernandez, C Subramony, U Ladabaum, E Boyd, W Zhao, A Mannalithara, A Sharabidze, G Singh, E Chung, T Levin, C Siegel, S Finlayson, B Sands, A Tosteson, C Kerner, K Carey, A Mills, W Yang, M Synnestvedt, S Hilton, M Weiner, J Lewis, J Altamirano, C Fagundes, M Dominguez, E Garcı ´a, J Michelena, A Ca ´rdenas, M Guevara, G Pereira, K Torres-Vigil, V Arroyo, J Caballerı ´a, P Gine, R Bataller
Journal: Clinical Gastroenterology and Hepatology (2011)
Beyond tort reform
Authors: K. B. Johnson
Journal: JAMA (1987)

It has been 2 1/2 years since the American Medical Association created national headlines by describing the professional liability situation facing physicians in this country as a "crisis." The American Medical Association's assertion touched off a national debate and signaled the beginning of a wave of medical malpractice tort reform efforts that hit Congress and virtually every state legislature. By the end of 1986 over 30 states had passed legislation that, bluntly stated, made it more difficult to sue physicians for large amounts of money. That is a remarkable record considering that, unlike the crisis of a decade ago, insurance has generally remained available at some price for the vast bulk of physicians. But few believe that this second wave of tort reform will permanently contain the problem. Even with the ardent support of nearly every organization in America that produces a product or provides a service—from the Boy Scouts
Leads from the MMWR. Summary of the Second National Community Forum on Adult Immunization
Journal: JAMA (1987)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Analysis of the mechanism of steroid hormone receptor-dependent gene activation in cell-free systems
Authors: M. K. Bagchi
Journal: Endocrine Reviews (1992)

Journal Article Analysis of the Mechanism of Steroid Hormone Receptor-Dependent Gene Activation in Cell-Free Systems Get access Milan K. Bagchi, Milan K. Bagchi 1Department of Cell Biology, Baylor College of Medicine Houston, Texas 77030 Search for other works by this author on: Oxford Academic Google Scholar Ming-Jer Tsai, Ming-Jer Tsai 1Department of Cell Biology, Baylor College of Medicine Houston, Texas 77030 *Address requests for reprints to: Sophia Y. Tsai, Ph.D., Department of Cell Biology, Baylor College of Medicine, 1 Baylor Plaza, Houston, Texas 77030. Search for other works by this author on: Oxford Academic Google Scholar Bert W. O'Malley, Bert W. O'Malley 1Department of Cell Biology, Baylor College of Medicine Houston, Texas 77030 Search for other works by this author on: Oxford Academic Google Scholar Sophia Y. Tsai Sophia Y. Tsai 1Department of Cell Biology, Baylor College of Medicine Houston, Texas 77030 Search for other works by this author on: Oxford Academic Google Scholar Endocrine Reviews, Volume 13, Issue 3, 1 August 1992, Pages 525–535, https://doi.org/10.1210/edrv-13-3-525 Published: 01 August 1992
Error in Data Presentation
Journal: JAMA Network Open (2020)

Kei Ouchi, MD, MPH; Tania Strout, PhD, RN, MS; Samir Haydar, DO, MPH; Olesya Baker, PhD; Wei Wang, PhD; Rachelle Bernacki, MD, MS; Rebecca Sudore, MD; Jeremiah D. Schuur, MD, MHS; Mara A. Schonberg, MD, MPH; Susan D. Block, MD; James A. Tulsky, MD
The letter or the spirit. Consent for research in CPR
Authors: C. M. Olson
Journal: JAMA (1994)

Major scientific advances may begin serendipitously. The idea for active compression-decompression cardiopulmonary resuscitation (ACD CPR) came from an anecdotal account of successful resuscitation using a toilet plunger.<sup>1</sup>Subsequent research supported the concept, as better cardiovascular hemodynamics among animals<sup>2,3</sup>or humans<sup>4-7</sup>or better short-term survival among humans<sup>8,9</sup>was found with ACD CPR compared with standard CPR. One study even suggested that ACD CPR might improve neurological outcomes, as pigs receiving ACD CPR had better cerebral hemodynamics, oxygenation, and metabolism.<sup>10</sup> This issue ofThe Journaldescribes a study<sup>11</sup>of ACD CPR that was terminated by the US Food and Drug Administration (FDA) before completion, primarily because of concerns about informed consent. The project was funded by Ambu International, the maker of the Ambu CardioPump ACD CPR device; there was no federal support. The protocol had been approved by the institutional review board (IRB) of the St
Clofarabine, Idarubicin, and Cytarabine (CIA) As Frontline Therapy for Patients Younger Than 61 Years with Newly Diagnosed Acute Myeloid Leukemia (AML)
Authors: Aziz Nazha, Farhad Ravandi, Hagop M. Kantarjian, Guillermo Garcia-Manero, Elias Jabbour, Gautam Borthakur, Tapan Kadia, Marina Konopleva, Jorge E. Cortes, Alessandra Ferrajoli, Steven M. Kornblau, Michael Andreeff, Min Du, Mark Brandt, Stefan Faderl
Journal: Blood (2011)
Herpes zoster and neurogenic bladder dysfunction
Authors: A. K. Izumi
Journal: JAMA (1973)

Two cases of herpes zoster were associated with neurogenic bladder dysfunction. The zosteroid eruption involved the sacral nerve distribution (S2-4) in both cases. Associated symptoms of constipation and massive bladder hemorrhage in one case and clinical recognition and conservative management of neurogenic bladder dysfunction association with herpes zoster are stressed.
Progressive multifocal leukoencephalopathy in AIDS
Authors: R. E. Chaisson
Journal: JAMA (1990)

<h3>CASE PRESENTATION</h3> —John Williams, MD A 42-YEAR-OLD bisexual, white man presented complaining of progressive memory loss, confusion, and difficulty speaking for 1 week. The patient had been diagnosed with acquired immunodeficiency syndrome (AIDS) a year earlier when he developed cutaneous Kaposi's sarcoma. Three months before admission,<i>Pneumocystis</i>pneumonia was diagnosed and treated. At that time, radiation therapy for his cutaneous Kaposi's lesions was performed. A month prior to admission, he was found to have Kaposi's sarcoma of the upper gastrointestinal tract. On admission he denied fever, sweats, headache, stiff neck, photophobia, seizures, or focal weakness. His medications were a combination product of sulfamethoxazale and trimethoprim and clotrimazole troches. Physical examination showed a temperature of 37°C; pulse rate, 82 beats per minute; blood pressure, 127/79 mm Hg; and respirations, 18/min. Notable physical findings included the cutaneous lesions of Kaposi's sarcoma, a 2/6 systolic ejection murmur at the left sternal border, and
Comparison of doxorubicin and cyclophosphamide (AC) versus single-agent paclitaxel (T) as adjuvant therapy for breast cancer in women with 0-3 positive axillary nodes: CALGB 40101.
Authors: Lawrence N. Shulman, Donald A. Berry, Constance T. Cirrincione, Heather Becker, Edith A. Perez, Ruth O'Regan, Silvana Martino, Charles L. Shapiro, James Atkins, Charles Schneider, Gretchen Genevieve Kimmick, Harold J. Burstein, Larry Norton, Hyman Bernard Muss, Clifford Hudis, Eric P. Winer
Journal: Journal of Clinical Oncology (2013)

1007 Background: Determining optimal adjuvant chemotherapy for early stage breast cancer depends on efficacy and toxicity. We sought to determine if T is equivalent to AC but with reduced toxicity. Methods: Pts with operable breast cancer with 0-3 positive nodes were enrolled on a 2x2 factorial design study which addressed (1) superiority of 6 vs. 4 cycles of therapy (previously reported, Shulman, JCO 2012) and (2) equivalence of single-agent T to standard AC, defined as upper bound of 95% confidence interval (CI) of hazard ratio (HR) of T vs. AC &lt; 1.30 for the primary endpoint of relapse-free survival (RFS). A planned target of 567 RFS events required 4,646 pts with 4 yrs FU. At activation in 2002, T (80mg/m2) was q1wk for 12 or 18 wks and AC (60/600 mg/m2) was q3wk for 4 or 6 cycles. In 2003 (570 pts enrolled) schedules were revised to 4 or 6 cycles q2wk for both T (175 mg/m2) and AC. The 6-cycle arms were dropped in 2008 (3,171 pts enrolled) due to slow accrual. Relative effectiveness of T to AC is shown by hazard ratio (HR). Logrank p-values are measures of discordance but are not relevant for the equivalence question and are not adjusted for multiple comparisons. Results: After enrolling 3,871 pts, the study closed in 2010 due to slowing accrual. With a median follow-up of 6.1 yrs there are 437 RFS events. The HR of 1.26 (95% CI: 1.05-1.53; p = 0.02) does not allow a conclusion of equivalence of T with AC. With 266 deaths the HR for overall survival (OS) is 1.27 (95% CI=1.00-1.62; p = 0.05), favoring AC. The estimated absolute advantage of AC at 5 yrs is 3% (91 vs. 88%) for RFS and 1% (95 vs. 94%) for OS. All 9 treatment-related deaths were in pts receiving AC and are included in the survival analysis. The incidence of Grade 3+ toxicity for AC vs T was 33% vs. 4% for hematologic toxicity and 36% vs 22% for non-hematologic toxicity. Conclusions: This trial did not show equivalence of T to AC, a conclusion that is very unlikely to change with additional follow-up. T was less toxic than AC. Clinical trial information: CDR0000069444/NCT00041119.
Copyright
Authors: N Milpied, B Vasseur, N Parquet, J Gamier, C Antoine, P Quartier, A Carret, D Bouscary, A Faye, B Bourbigot, Y Reguerre, A Stoppa, P Bourquard, B Hurault De Ligny, F Dubief, A Mathieu-Boue, V Leblond, / Foran, D Cunningham, B Coiffier, P Solal- Celigny, F Reyes, M Ghielmini, P Johnson, C Gisselbrecht, M Bradburn, J Matthews, T Lister, S.-F Hsu Schmitz, K Bu'rki, G Pichert, D Betticher, R Stupp, M Wernli, A Lohri, D Schmitter, F Bertoni, T Cerny, " Stilgenbauer, C Schaffner, D Winkler, G On, E Leupolt, M Bentz, P Moller, H Muller- Hermelink, M James, P Lichter, H Dohner, M Chesi, W Kuehl, P Bergsagel, A Lopez-Guillermo, F Cabanillas, P Mclaugh- Lin, T Smith, F Hagemeister, M Rodriguez, J Romaguera, A Younes, A Sam's, H Preti, W Pugh, M.-S Lee, K Seidemann, G Henze, J Beck, A Sauerbrey, J Kiihl, G Mann, A Reiter, N Mikhaeel, A Timothy, S Hain, M O'dohertv
Journal: Annals of Oncology (2000)
Journal Investigative Dermatology, Baltimore
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 3290: G674A Polymorphism of the Connexin 40.1 Gene and Atrial Fibrillation in Patients With Dilated Cardiomyopahty
Authors: Akiyoshi Ogimoto, Hideki Okayama, Tomoaki Ohtsuka, Jun Suzuki, Akira Kurata, Kazuhisa Nishimura, Takayuki Nagai, Makoto Saito, Tetsuro Miki, Jitsuo Higaki
Journal: Circulation (2007)

Background: Atrial fibrillation (AF) is the most common type of cardiac arrhythmia and a leading cause of cardiovascular morbidity. The cardiac gap-junction protein connexin is expressed in atrial myocytes and mediates the coordinated electrical activation of the atria. Some polymorphisms in connexin genes were reported to be significantly associated with AF. We hypothesized that polymorphism (G674A) in the connexin 40.1 gene may be associated with AF in patients with dilated cardiomyopathy (DCM). Methods and Results: We genotyped this polymorphism (G674A, rs595652 ) in 83 patients with DCM by using the TaqMan chemical method. Patients were classified into AF group (n=21) if they had AF, and sinus rhythm (SR) group (n=62) if they had SR. Distribution of the connexin 40.1 genotypes (G/G, G/A, and A/A) among the total patients with DCM was 27.7%, 54.2%, and 18.1%, respectively. Allele frequency for the A allele was 0.52 in the AF group and 0.43 in the SR group. In a dominant G allele model (G/G and G/A genotypes vs A/A genotype), there was a significant difference in genotypes between the AF group and the SR group (p=0.035). This table shows odds ratios for atrial fibrillation in patients with DCM determined by logistic regression analysis. The odds of AF in DCM patients with the A/A genotype was 3.38-fold. In addition, age and left atrial dimension were also risk factors. Conclusion: The A/A genotype in the connexin 40.1 gene is a significant risk factor for AF in patients with DCM. Odds Ratios* for Atrial Fibrillation
Relationship of cardiac problems to athletic participation
Authors: K. D. Rose
Journal: JAMA (1969)

A rapid electrocardiographic technique, using a semireclining chair fitted with copper skin electrodes for arms and legs, has been employed in a screening survey of athletes during the routine preseason physical examinations. Mutually perpendicular leads I and aVF were recorded on 1,219 candidates. Following standards set by Dawber and Katz, 1,158 were normal, 51 doubtful, and 10 abnormal. Based on current knowledge, Wolff-Parkinson-White syndrome without history of paroxysmal arrhythmia is acceptable for strenuous sports; acquired bundle-branch block, right or left, should be suspected and thoroughly investigated; nodal rhythm and other second-degree block aggravated by exercise is cause for rejection as is myocardial ischemia and active myocarditis but not isolated T-wave changes. Cardiac contusion should be suspected in injuries of the anterior portion of the chest, and the patient should be permitted to play only when fully recovered.
Uterine aspiration for evacuation of the pregnant uterus
Authors: C. J. Eaton
Journal: JAMA (1969)

Uterine aspiration was employed in 200 pregnant patients with incomplete abortions, molar pregnancies, or to effect therapeutic abortion. In patients with incomplete abortion, the procedure was a complete one through the 12th week and was effective in reducing uterine size in the remainder. It was also effective for the evacuation of molar pregnancy and in therapeutic abortion. There were no complications in any of these patients attributable to uterine aspiration.
Abstract 13245: Clinical Correlates and Heritability of Cardiac Mechanics: Insights from the HyperGEN Study
Authors: Sadiya S Khan, Kwang-Youn A Kim, Jie Peng, Frank G Aguilar, Senthil Selvaraj, Eva E Martinez, Abigail S Baldridge, Marguerite R Irvin, Jin Sha, Ulrich Broeckel, Donna K Arnett, Sanjiv J Shah
Journal: Circulation (2014)

Introduction: A genetic predisposition to abnormal cardiac mechanics may explain the familial predisposition to heart failure (HF). We hypothesized that indices of cardiac mechanics (speckle-tracking strain parameters and tissue velocities) are heritable traits. Methods: We performed speckle-tracking analysis on echocardiograms and measured global longitudinal, circumferential, and radial strain (GLS, GCS, GRS), early diastolic strain rate, and e’ velocities in the HyperGEN study, a family- and population-based study of hypertension (N=2058 [54% African American (AA)]). Additive genetic heritability estimates for cardiac mechanics were calculated by maximizing the likelihood variance components in SOLAR (ver.6) adjusted for age, sex, race, height, weight, systolic blood pressure (SBP), left ventricular (LV) mass, ejection fraction, reader, image quality, and institution. Results: Mean age was 51±14 years and HF risk factors were common: hypertension (56%), obesity (47%), and diabetes (16%). Clinical and conventional echocardiographic characteristics, including male gender, hypertension, elevated fasting glucose, higher body-mass index, and LV hypertrophy were all significantly associated with increased absolute GLS and septal e’ velocity (P&lt;0.05). After adjustment for covariates (and correlation within the same families), genetic contributions remained significant in GLS and septal e’ velocity in all participants, a finding which persisted in race-stratified analyses (Table). Conclusions: Echocardiographic measures of cardiac mechanics, particularly GLS and e’ velocity, are heritable traits, even after adjustment for clinical and cardiac structural factors (e.g., SBP and LV mass, respectively) that are known to be heritable and associated with cardiac mechanics. These data support the exploration of genetics of cardiac mechanics, which may provide insight into the molecular pathogenesis of LV dysfunction and HF.
Toxicology
Journal: JAMA (1999)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Chromite Ore Processing Residue in Hudson County, New Jersey
Authors: Thomas Burke, Jerry Fagliano, Marcia Goldoft, Robert E. Hazen, Raja Iglewicz, Thomas McKee
Journal: Environmental Health Perspectives (1991)

Chromite ore processing residue occurs at over 130 sites in Hudson County, New Jersey. Many of these sites are in urban residential areas. This waste is a result of 70 years of chromate and bichromate chemical manufacturing. At least 15% of the sites contain total chromium concentrations greater than 10,000 mg/kg, with hexavalent content ranging from about 1 to 50%. Continuing leaching of this waste results in yellow-colored surface water runoff and yellow deposits on the soil surface and inside basement walls. The chemistry, environmental fate, health effects, and human exposure potentials for this waste are described.
A HOUSE ENDEMIC OF MALARIA.
Journal: JAMA (1903)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal