tbuckley/cabot-search huggingface dataset:
Anatomie und Pathologie der Spontanerkrankungen der kleinen Laboratoriumstiere: Kaninchen, Meerschweinchen, Ratte, Maus.
Journal: JAMA (1931)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
CELERY AS A VEHICLE OF INFECTION.
Journal: JAMA (1900)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Highlights from Recent Cancer Literature
Journal: Cancer Research (2010)

Abnormal activation of the RAS-RAF-MEK-ERK signaling pathway is a common feature of many human solid tumors.Based on this observation, several RAF and MEK inhibitors have been developed and are currently being evaluated in clinical trials; however, an unexpected, albeit not entirely surprising complication has emerged.Clinical trials in patients with metastatic melanoma have shown positive therapeutic effects following treatment with PLX4032, a compound that is thought to selectively inhibit BRAF V600E , a common mutation found in melanoma associated with increased BRAF activity.However, it is now clear that, despite the positive response to PLX4032, some patients have developed hyperproliferative skin lesions, and in a few instances, squamous cell carcinomas, which regressed after drug cessation.Three recently published studies have begun to unravel the complexity of this signaling conundrum and now provide an explanation for the unanticipated outcomes.These authors and their colleagues have found that, whereas selective BRAF inhibitors suppress RAF-MEK-ERK signaling in BRAF-mutant melanoma cells, they unexpectedly activate the pathway in cells carrying an oncogenic KRAS mutation, common to squamous carcinomas, but which possess a wild-type BRAF gene that favors activity of the MEK-ERK pathway.
SAT0249 Reference Intervals of Spinal Mobility Measures in Normal Individuals – The Mobility Study
Authors: S. Ramiro, C. Stolwijk, A. van Tubergen, D. van der Heijde, P. Royston, R. Landewé
Journal: Annals of the Rheumatic Diseases (2013)

<h3>Background</h3> Spinal mobility is frequently assessed in the follow-up of patients with axial SpA, which is also in accordance with the recommendations by the Assessment of Spondyloarthritis international Society (ASAS). However, the interpretation of spinal mobility measures has been hampered by the absence of reference values. <h3>Objectives</h3> To establish reference intervals (RIs) for spinal mobility measures. <h3>Methods</h3> A cross-sectional study (“MOBILITY-study”) was conducted among healthy volunteers aged 20-69 years old. Recruitment was stratified by gender, age (10-year categories) and height (10cm categories). Participants were Caucasian volunteering to be measured in either the Netherlands or Portugal. Exclusion criteria were factors potentially influencing spinal mobility (eg. back surgery, low back pain). Several spinal mobility measures were assessed: lateral spinal flexion (LSF, cm), cervical rotation (degrees), intermalleolar distance (cm), chest expansion (cm), 10cm- and 15cm-Schober’s test. The Bath Ankylosing Spondylitis Mobility Index (BASMI) was computed. Age-specific equations for percentiles of spinal mobility measures were derived by maximum likelihood. Each parameter of normal or exponential-normal density was modeled as a fractional polynomial function of age. The estimated 95% RI (2.5<sup>th</sup> and 97.5<sup>th</sup> percentiles), as well as the 5<sup>th</sup>, 10<sup>th</sup>, 25<sup>th</sup> and 50<sup>th</sup> percentiles, are presented. RIs can be computed for any age, but examples were chosen for the ages of 25, 35 and 45, for comparison purposes with mobility measurements of patients with axial SpA. <h3>Results</h3> 393 volunteers were included (only the category of 60-69 year-old women with height &gt;1.80m was incomplete, due to difficulties in recruitment). RIs were derived and are presented in the Table. Percentiles graphs were also plotted for each of the measurements, with the best-fitting equation. The lower border of the RI for both Schober’s 10cm and 15cm test lies below the “cutoff” of 5cm frequently used in clinical practice. No individual had a BASMI&lt;0.15, being the median value of 1.3 for a patient of 25 years old and increasing with age. <h3>Conclusions</h3> Age-specific RIs and percentiles were derived for each of the spinal mobility measures for normal individuals. These RIs may guide clinicians when assessing the mobility of patients with axial SpA, and may serve as cut-off levels for ‘normal’ vs. ‘abnormal’. <h3>Disclosure of Interest</h3> None Declared
Empire Rheumatism Council: Fourteenth Annual Report
Journal: Annals of the Rheumatic Diseases (1951)

indirect evidence, that the aetiology was gonococcal.The failure to respond to cortisone was interesting in view of the three cases recently successfully treated in Toronto.(5) Sjogren's Syndrome (shown by Dr. F. Dudley Hart).A woman, aged 64, recently under the care of Dr. J. L. Lovibond, differed from most of the cases reported by Sjogren in that she looked younger than her age.She had suffered from kerato-conjunctivitis sicca and dryness of nose and mouth for 20 years.Arthritis had developed within the last three years and was still active and progressing.Dr. Hart asked if there was any evidence that such cases were anything more than a chance association of kerato-con- junctivitis sicca and rheumatoid arthritis.Dr. J. H. Kellgren spoke of recent work in the Rheumatism Research Centre in Manchester.He had found that about 10 per cent. of elderly rheumatoids and a somewhat lower percentage of non-rheumatoids had dry eyes.Dr. W.
Twenty=ninth Annual Registration Report of Births, Marriages and Deaths in Michigan for 1895.
Journal: JAMA (1897)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Using end-stage renal disease facility surveys to monitor end-stage renal disease program trends. The Data Committee of the National Forum of End-Stage Renal Disease Networks
Journal: JAMA (1985)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Incidence of Human Maldevelopment
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Changing patterns of asthma hospitalization among children: 1979 to 1987
Authors: P. J. Gergen
Journal: JAMA (1990)

The National Hospital Discharge Survey was used to evaluate the trends in asthma hospitalizations among children under<i>International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM)</i>: 1979 to 1987. During this period, asthma hospitalizations among children aged 0 to 17 years increased 4.5% per annum (95% confidence interval [CI], 2% to 7.1%). The increase was largest among 0 to 4 year olds, 5.0% per annum (95% CI, 3.4% to 6.7%), vs 2.9% per annum (95% CI, -0.3% to 6.2%) observed among 5 to 17 year olds. Among children aged 0 to 4 years, blacks had approximately 1.8 times the increase of whites. During this time, total hospitalizations decreased - 4.6% (95% CI, - 6.6% to - 2.5%), while admissions for lower respiratory tract disease had a statistically insignificant decrease: -1.3%. Acute and chronic/unspecified bronchitis hospitalizations decreased -6.1% (95% CI, -9.4% to -2.7%), but this decrease did not begin until 1983. Thus, a shift in coding from bronchitis to asthma does not seem to fully explain the increase. (<i>JAMA</i>. 1990;264:1688-1692)
Edema Universalis?
Authors: Joseph Zeisler
Journal: JAMA (1897)

Chicago, Nov. 13, 1897. <h3>To the Editor:</h3> —Med. Dr. Gustavus M. Blech desires to know, in the last number of theJournal, whether a certain case observed by him is justly called by him "edema universalis?" Certainly not. It should be called "edema universale." The meager description offered allows no definite diagnosis, but it seems probable that the edema was due to "sclerema neonatorum."
The First Year of Life.
Journal: JAMA (1930)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Memorandum on Poisons.
Journal: JAMA (1892)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
NORWAY
Journal: JAMA (1962)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
RITUALISTIC SANITATION OF THE JEWS.
Journal: JAMA (1907)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Course of Lectures on the Surgery of the Kidney: Delivered at the Middlesex Hospital
Authors: H. Morris
Journal: BMJ (1893)

MY remarks on this important operation will be based chiefly upon 23 cases in which I have myself operated, but the opinions and conclusions which I have formed have in part also been shaped by about half as many more cases in which I have been either a spectator or an assistant at the operations of other surgeons. CLASSIFICATION OF CASES.I have divided my own cases into four groups, according to the nature of the diseases for which nephrectomy was under- taken.They are as follow: (a) Solid tumours, 5 cases; (b) hydronephrosis and hydronephrotic cysts, 6 cases; (c) cal- culous affections, chiefly pyonephrosis, 7 cases; (d) tuberculous disease, 5 cases.TEE METHOD OF OPERATION.An experience of nephrectomy in a fairly considerable variety ot cases such as this list furnishes has convinced me of three important facts: (1) The selection of the method of operating must depend upon the nature of the disease, and in matters of detail the operation selected will vary greatly in different cases of the same disease; (2) the mortality varies much more with the nature of the disease than with the method of operating; (3) where an operator does not select his cases with an eye to the effect that each one will be likely to make upon his statistical results, the death-rate really due to the operation itself and the dangers of the operation will always appear larger than they really are.CAUsEs OF MORTALITY.I will take the last point first, leaving the other two for the conclusion of this lecture.Now, the only way to arrive at a just appreciation of the mortality is to consider each fatal case individually, with this question in mind, Was death caused by the operation, or would the patient certainly have
CME Hiatus: July Through December 2002
Authors: Alan Geller, Donald Miller, Scd George, David Annas, Marie-France Demierre, Barbara Gilchrest, Howard Koh
Journal: JAMA (2002)

Comment.We found persistent decreases in mortality over a 30-year period among Americans aged 20 through 44 years, and little change for women aged 45 through 64 years.These mortality trends reflect declining rates of melanoma case fatality.Moreover, incidence rates in the youngest age groups have not continued to increase as they have for older Americans.Mortality trends are also consistent with earlier birthcohort analyses suggesting an anticipated leveling off and decline in melanoma death rates. 2 Mortality data also reflect recent studies in which melanoma incidence rates declined more for distant-stage tumors among women than among men and rates for thick tumors (Ͼ4 mm) increased significantly only in men aged 60 years and older. 3 Mortality reductions for this strongly sun exposureassociated malignancy 4 in younger Americans suggests positive effects of public education during the past 30 years.However, as incidence rates among middle-aged and older men continue to increase and the proportion of thick melanoma remains high, concerted efforts must be made for outreach and early detection for this at-risk group now characterized by decades of excessive sun exposure.Thus, the Third United States Preventive Services Task Force ( 2001) and
Gauze Carrier.
Authors: CLINTON T. COOKE
Journal: JAMA (1900)

The accompanying cuts illustrate an instrument designed to introduce gauze into cavities in, or orifices of, the body for drainage purposes or for controlling hemorrhage. The instrument consists of a body tube twelve inches long (I am describing size 3), one-fifth of an inch outside diameter, having two ring handles attached to its upper end, for the index and middle finger, and having within it an inner retarding tube provided with a flange above and so cut out below as to form three spurs, which project slightly into the lumen of the lower end of the tube, permitting forward movement but preventing any backward movement of the gauze when the packer is moved back to obtain a fresh hold on the gauze. A cap screws on to the upper end of the body tube to hold the retarding tube in place, having an opening in its top equal in size
Health Policy
Journal: JAMA (1998)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal