tbuckley/cabot-search huggingface dataset:
Abstract P263: Adjudication of Heart Failure (HF) in an Electronic Cohort of Human Immunodeficiency Virus-infected (HIV+) Persons
Authors: Alexandra B Steverson, Anna E Pawlowski, Daniel Schneider, Prasanth Nannapaneni, Jes M Sanders, Chad J Achenbach, Sanjiv J Shah, Donald M Lloyd-Jones, Matthew J Feinstein
Journal: Circulation (2017)

Background: Analyses of administrative data suggest that HIV+ persons have elevated risks for HF from HIV-related and traditional cardiovascular disease (CVD) risk factors. However, none of these studies adjudicated HF diagnoses, which is essential given poor agreement between administrative coding and physician adjudication. We sought to create a reproducible protocol for identifying and adjudicating HF in HIV+ persons and to compare characteristics between those with and without adjudicated HF. Methods: We screened for and adjudicated HF diagnoses in a cohort of 5,052 HIV+ persons receiving care at an academic center. Screening for possible HF included any of the following: 1) HF diagnosis code, 2) B-type natriuretic peptide (BNP) &gt;100 pg/mL, or 3) intravenous diuretic use. Two physicians then independently reviewed all records. Definite HF was adjudicated if all of the following were present: HF symptoms, physician diagnosis, HF medication use, and objective evidence of myocardial dysfunction. Demographics and clinical characteristics were compared for HIV+ patients with screened+/adjudicated+ HF, screened+/adjudicated- HF, and those who screened- for HF. Results: There was &gt;96% agreement in HF diagnoses between the two adjudicators (Kappa = 0.91). Race differed significantly across the three groups, with more black patients among those with adjudicated+ HF (Table 1). Patients with adjudicated+ HF were significantly more likely than patients who screened+/adjudicated- HF to have diabetes, hypertension, atrial arrhythmias, a diagnosis of myocardial infarction, and any smoking history (p&lt;0.001 for all). Patients who screened+ for HF (whether adjudicated+ or -) tended to have more advanced HIV than those who screened- based on nadir CD4 T cell count and peak HIV viral load (Table 1). Conclusions: There are significant clinical differences between HIV+ patients with and without adjudicated HF. These findings underscore the importance of adjudicating HF in future studies characterizing CVD for HIV+ persons.
Leukemia and radium groundwater contamination
Authors: B. L. Tracy
Journal: JAMA (1986)

<h3>To the Editor.—</h3> In the Aug 2, 1985, issue of<i>JAMA</i>, Lyman et al<sup>1</sup>claim to have shown an association between leukemia incidence in Florida and radium in groundwater supplies. Although cautious in their conclusions, the authors imply that this excess in leukemia was in fact caused by radiation. We believe they have not presented a convincing argument for causation. The radiation doses at these levels of exposure could account for only a tiny fraction of the leukemia excess. Lyman et al report that 27.6% of tested wells in the high-exposure counties exceeded the Environmental Protection Agency guideline for radium (5 pCi/L) and had a geometric mean radium concentration of 9.5 pCi/L. We conservatively assume that the tested wells were representative of all water supplies of these counties and thus that 27.6% of the populationwas exposed to radium at 9.5 pCi/L. With a per capita water consumption of
Neurological Fragments.
Journal: JAMA (1926)

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John Jeffries
Authors: Renwick K. Caldwell
Journal: New England Journal of Medicine (1961)

WITH the following hesitant preface Dr. John Jeffries, in 1785, introduced the earliest American work on aeronautics and apologized for his scientific interest in the vast world above the earth:After so many accounts of Aerial Voyagers have been laid before the Public, some apology on my part, for attempting to obtrude the following, seems almost indispensable.Although his instruments and methods were crude, many of his observations have been confirmed, and, with the current interest in space, it is fitting to recall the interesting story of this early scientist and adventurer.Born in Boston in 1744 and an honor . . .
Youth and the Future
Journal: JAMA (1942)

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Pulmonary immune cells in health and disease: the eosinophil leucocyte (Part I)
Authors: C Kroegel, None Virchow JC, W Luttmann, C Walker, JA Warner
Journal: European Respiratory Journal (1994)

Increasing evidence has accumulated to suggest that eosinophils play a key role in the pathogenesis of asthma and other pulmonary diseases by damaging infiltrated bronchial tissue and lung parenchyma. The first part of this review on eosinophils describes the cellular characteristics and properties of the cell, which help in understanding its role in disease. The article focuses on origin, maturation and differentiation of the eosinophil, its morphological and phenotypical properties, as well as its preformed and newly generated mediators of inflammation. The cause and putative significance of eosinophil heterogeneity in respect to function and density will also be discussed. In addition, the naturally occurring mediators through which eosinophils are activated and communicate with other inflammatory cells are outlined. The first part closes with new aspects of eosinophil recruitment from the circulation into perivascular tissue, including nonselective and putative selective adhesion mechanisms and chemotaxis.
The World in Medicine
Authors: Rebecca Voelker
Journal: JAMA (1997)

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Atlas of Neuropathology
Journal: JAMA (1949)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Atmospheric Chemistry of Gas-Phase Polycyclic Aromatic Hydrocarbons: Formation of Atmospheric Mutagens
Authors: Roger Atkinson, Janet Arey
Journal: Environmental Health Perspectives (1994)

The atmospheric chemistry of the 2-to 4-ring polycyclic aromatic hydrocarbons (PAH), which exist mainly in the gas phase in the atmosphere, is dis- cussed.The dominant loss process for the gas-phase PAH is by reaction with the hydroxyl radical, resulting in calculated lifetimes in the atmos- phere of generally less than one day.The hydroxyl (OH) radical-initiated reactions and nitrate (NO3) radical-initiated reactions often lead to the for- mation of mutagenic nitro-PAH and other nitropolycyclic aromatic compounds, including nitrodibenzopyranones.These atmospheric reactions have a significant effect on ambient mutagenic activity, indicating that health risk assessments of combustion emissions should include atmospheric transformation products.-
A Handbook of Renal Surgery.
Journal: JAMA (1927)

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<i>QuickStats:</i> Rate* of Alcohol-Induced Deaths† Among Persons Aged ≥25 Years, by Age Group — National Vital Statistics System, 1999–2017
Journal: MMWR Morbidity and Mortality Weekly Report (2019)

Rates of alcohol-induced deaths for persons aged 45-64 years increased from 17.3 per 100,000 population in 1999 to 26.0 in 2017.For persons aged 25-44 years, rates declined from 1999 to 2005, were stable from 2005 to 2012, and then increased from 2012 (4.8) to 2017 (6.3).A similar pattern was observed for persons aged ≥65 years, with an initial decline, a stable period, and then an increase from 2011 (12.0) to 2017 (16.4).
ANOTHER MOUNTAIN MALADY
Journal: JAMA (1962)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
South African J of Radiology, Cape Town
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The volume-staffing-outcome relationship: A population-based study of moderate-risk cancer surgery
Authors: L. S. Elting, C. Cooksley, C. Pettaway, B. N. Bekele, E. B. C. Avritscher, H. B. Grossman, P. Mansfield, C. P. N. Dinney
Journal: Journal of Clinical Oncology (2004)

6025 Background: Patients (pts) are referred to high-volume (Hi Vol) hospitals (hosps) for high-risk cancer surgery (pancreatectomy, esophagectomy) because peri-operative mortality is significantly lower at such hosps. For moderate-risk procedures (mortality 1%–5%), the benefit of Hi Vol hosps is significant, but modest. The value of referral for these common procedures is unclear, but alternatives are lacking. We hypothesized that, independent of procedure volume, hosps with high staff-to-bed ratios would have lower mortality after moderate-risk cancer surgery. Methods: We studied inpatient claims of pts who underwent 3 moderate risk procedures (segmental or wedge resection of lung, 646 lung ca pts; partial or total cystectomy, 1510 bladder ca pts; partial colectomy, 14,948 colon ca pts) between 1/99 and 12/01 in all Texas hosps, except federal. We studied the relationship between inpatient mortality and hosp staffing, using a random effects logit model to account for clustering of pts within hosps. Staffing factors included registered nurse (RN)-, total nursing staff-, and respiratory therapist-to-occupied bed ratios. We adjusted for confounding pt factors (age > 75 yrs, African-American race, Hispanic ethnicity, low income, male sex, chronic comorbidity, metastases, cancer site) and hosp factors (teaching status, rural location, for-profit ownership, total annual surgeries). Results: 17,104 pts were treated at 273 hosps. 51% were male, 37% were >75 yrs, 11% were African-American, and 13%, Hispanic. Inpatient mortality was 4% for segmental lung resection, 2.2% for cystectomy, and 3.2% for partial colectomy. After adjusting for confounding, treatment at a Hi Vol hosp (OR=0.74; p = 0.001) and a high RN-to-bed ratio (OR=0.80; p = 0.02) predicted significantly lower inpatient mortality. These findings were consistent overall and for each procedure individually. Total nurse and respiratory therapist staffing did not predict mortality. Conclusions: A high RN-to-bed ratio is a significant predictor of low peri-operative mortality after moderate risk procedures. Increasing RN staffing could improve outcomes in low vol centers. No significant financial relationships to disclose.
Newer Remedies: Including their Synonyms, Sources, Methods of Preparation Tests, Solubilities, Incompatibles, Medicinal Properties, and Doses as far as Known, Together with Sections on Organotherapeutic Agents and Indifferent Compounds of Iron. A Reference Manual for Physicians, Pharmacists and Students.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
MYCOSIS FUNGOIDES
Authors: J. H. STOWERS
Journal: British Journal of Dermatology (1903)

Journal Article MYCOSIS FUNGOIDES Get access J. H. STOWERS, M.D J. H. STOWERS, M.D Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 15, Issue 2, 1 February 1903, Pages 47–63, https://doi.org/10.1111/j.1365-2133.1903.tb16477.x Published: 01 February 1903
Incorrect Affiliation
Journal: JAMA (1983)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 18294: Left Ventricular Systolic Dysfunction Early After Resuscitation From Cardiac Arrest is Associated With Shockable Arrest Rhythm
Authors: Jacob C Jentzer, Hussein Abu-Daya, Asher Shafton, Meshe Chonde, Didier Chalhoub, Andrew Althouse, Jon Rittenberger
Journal: Circulation (2015)

Introduction: Left ventricular systolic dysfunction (LVSD) is common after resuscitation from cardiac arrest (CA). The association of echocardiographic LVSD with cardiac rhythm during CA is not well described. Hypothesis: Patients with a shockable rhythm (VT/VF) will have a greater degree of LVSD by echocardiography after CA. Methods: Prospective registry of patients resuscitated from CA underwent transthoracic echocardiography (TTE) within 24 hours after CA. We determined 2D measurements, LVEF, spectral Doppler of mitral inflow and LV outflow, systolic and diastolic tissue Doppler of the mitral annulus velocity, and tricuspid plane annular excursion (TAPSE). We collected data on in-hospital mortality as well as vasopressor doses and troponin I levels. TTE parameters and clinical characteristics were compared between patients with a shockable (VT/VF) arrest rhythm and a non-shockable (asystole/PEA) arrest rhythm and between survivors and non-survivors using t-tests and ANOVA. Results: Of the 55 patients, the 23 (42%) with shockable CA rhythms had significantly higher LV end-systolic dimension (4.1cm vs. 3.3cm, p = 0.0073), lower LV fractional shortening (0.15 vs. 0.28, p &lt;0.0001), and lower LVEF both by visual estimate (36.2% vs. 52.3%, p = 0.0012) and by Simpson’s biplane method (37.5% vs. 52.3%, p = 0.0506). Other measured TTE parameters did not differ between groups, including TAPSE (shockable 1.53 vs. non-shockable 1.82, p = 0.1731). Admission and peak 24 hour vasopressor requirements did not differ between groups. Peak troponin levels were higher (22.26 vs. 3.88, p = 0.0198) in patients with shockable CA rhythms, but admission troponin levels were no different (0.88 vs. 0.51, p = 0.1527). TTE parameters did not differ between survivors and non-survivors (visual LVEF 47.0% vs. 44.2%, p = 0.5968; LV fractional shortening 0.19 vs. 0.25, p = 0.0916). Conclusions: Patients with shockable CA rhythms have more severe LVSD on 24 hour echocardiography despite similar vasopressor requirements and admission troponin levels. Echocardiographic parameters at 24 hours did not predict in-hospital mortality. Early echocardiography after CA appears more useful for differentiating primary CA rhythm than for predicting mortality.