tbuckley/cabot-search huggingface dataset:
Ipsilateral Blindness after Carotid Ligation for Carotid-Cavernous Fistula
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Über funktionelle Veränderungen der P- und T-Zacken im Elektrokardiogramm: Experimentelle Untersuchungen mit Ergotamin und Amylnitrit, sowie klinische Beobachtungen
Journal: JAMA (1941)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Thoracotomy increases peripheral airway tone and reactivity.
Authors: P Rock, A N Freed, D P Nyhan, P A Murray
Journal: American Journal of Respiratory and Critical Care Medicine (1995)

Our goal was to investigate the extent to which thoracotomy for chronic vascular instrumentation alters peripheral airway tone and reactivity. Using the wedged bronchoscope technique to measure peripheral airway resistance (RP), pentobarbital-fentanyl anesthetized, ventilated dogs were studied before and (16 +/- 2 d) after a left thoracotomy for chronic implantation of instrumentation to measure the left pulmonary vascular pressure-flow relationship. A map of the airways was constructed as bronchoscopes were advanced and wedged in the middle lobes of both the left and right lung. This allowed us to measure RP in the same sublobar region of the left and right lung both pre- and postoperatively. At the time of postoperative experimentation, all dogs appeared fully recovered from the surgical procedure. Compared with preoperative values, baseline RP (cm H2O.ml-1.s-1) was selectively increased (p < 0.03) postoperatively in the left (0.41 +/- 0.07 versus 1.27 +/- 0.36) but not in the right (0.29 +/- 0.06 versus 0.35 +/- 0.07) lung. Peripheral airway responses to acetylcholine, histamine, hypocapnia, and dry air challenges were all increased (p < 0.05) in both magnitude and duration in the left but not the right lung postoperatively. Total lung volume (helium dilution technique) was decreased (p < 0.01) by 10 +/- 3% postoperatively. However, similar reductions in lung volume were observed in the left and right lung. These results indicate that left thoracotomy for chronic instrumentation selectively increases left lung peripheral airway tone and reactivity, but has no effect on the right lung.
HYSTERICAL PSYCHOSIS
Authors: MARC H. HOLLENDER, STEVEN J. HIRSCH
Journal: American Journal of Psychiatry (1964)

The term hysterical psychosis has been in common usage for longer than half a century, but it has never become part of the standard nomenclature. Indeed, there is no single article in the literature in which hysterical psychosis as an entity is described and the subject discussed. We have set down how the term is used to provide a fixed point of reference for support or criticism. Our conceptualization of the process is essentially in agreement with Freud's formulation in his second article on the neuropsychoses insofar as we view the disturbance as a form of ego disruption. Descriptively, hysterical psychosis is marked by a sudden and dramatic onset temporally related to a profoundly upsetting event or circumstance. Its manifestations include hallucinations, delusions, depersonalization and grossly unusual behavior. Thought disorders, when they occur, are usually sharply circumscribed and very transient. Affectivity, if altered, is changed in the direction of volatility and not flatness. The acute episode seldom lasts longer than one to 3 weeks, and the eruption is sealed off so that there is practically no residue. Hysterical psychosis is encountered most commonly in persons referred to as hysterical characters or personalities when faced by trying life situations or problems. Statements received from correspondents were consistent generally with our viewpoint. Case notes have been presented to illustrate certain aspects of the clinical picture.
Diphtheria.
Authors: W. R. McMahon
Journal: JAMA (1891)

<h3>To the Editor:</h3> —Some twelve or fifteen years ago I wrote an article on diphtheria which was published in a local paper, claiming it to be an affection of the pneumo-gastric nerve. And now, after long and careful observation, I am impelled not only to confirm that earlier statement, but to add to it the result of maturer consideration by bringing to your notice a more detailed account of my idea of this troublesome disease. I believe the entire eighth pair of nerves to be affected. I believe the diphtheria microbe or bacterium to have an especial affinity for this pair of nerves, causing an inflammation of them, affecting particularly the glosso-pharyngeal and pneumo-gastric; but involving also, occasionally, the spinal accessory. If any medical gentleman will spend two hours in refreshing his memory on the exact distribution of the two first named, and then sit by the side of a
ABSTRACTS
Journal: Circulation (1959)

Repeated total serum cholesterol measurements were made in a group of 14 patients with recent acute imyocardial infaretion and Dieumarol therapy and compared with the control group composed of 10 normal men.The hospital group had an average of 10 determinations made on each individual and in the control group an average of 4 determinations were made.The total serum cholesterol in the control group was 226 mg./100 ml. with a standard deviation of 29.2.In the hospital group the total serum cho- lesterol averaged 266 mg./100 ml. with a standard deviation of 44.6.The diet of the control ,group was unrestricted while the hospital group received a regular hospital diet.In both groups the determinations fell within 40 ing./100ml. of the mean approximately 90 per cent of the time.The remaining 10 per cent of the determina- tions that fell outside the 40 mg./100 ml.decile may not be disregarded since 30 per cent of the control patients and 44 p-r cent of the hos- pital patients exhibited variations of this magni- tude at one time or another.The per cent variation of the most deviant determination against the mean was equally variable.Individuals in the control group exhibited variations from 6- 27 per cent and in the hospital group, from 3-29 per cent.Employing a t test the total serum cholesterol levels of the control group differed significantly from those of the hospital 1143
Evaluation of lapatinib as a component of neoadjuvant therapy for HER2+ operable breast cancer: NSABP protocol B-41.
Authors: Andre Robidoux, Gong Tang, Priya Rastogi, Charles E. Geyer, Catherine A. Azar, James Norman Atkins, Louis Fehrenbacher, Harry Douglas Bear, Luis Baez-Diaz, J. Phillip Kuebler, Richard G. Margolese, William Blair Farrar, Adam Brufsky, Henry R. Shibata, Hanna Bandos, Soonmyung Paik, Joseph P. Costantino, Sandra M. Swain, Eleftherios P. Mamounas, Norman Wolmark
Journal: Journal of Clinical Oncology (2012)

LBA506 Background: The purposes of this trial are to determine the effect of substituting lapatinib (L) for trastuzumab (T) in combination with weekly paclitaxel (WP) following AC as well as adding L to T with WP following AC on pathologic complete response (pCR) rates. Methods: Women with HER2-positive operable breast cancer received standard AC q3wks x 4 cycles followed by WP (80 mg/m 2 ) on days 1, 8, and 15 q28 days x 4 cycles. Concurrently with WP, patients received either T (4 mg/kg load, then 2 mg/kg) weekly until surgery, L (1250 mg) daily until surgery, or weekly T plus L (750 mg) daily until surgery. Following surgery, patients received trastuzumab to complete 52 wks of HER2-targeted therapy. The primary endpoint is pCR breast. For each of the two primary comparisons, the Fisher’s exact test was used to test the equality of pCR rates. A Hochberg-type step-up procedure was applied to address multiple testings and to control the family-wise error rate at 0.05. Results: 51% were clinically node positive and 63% had HR+ tumors. pCR assessments were available from 519 of 529 patients. pCR percentage was 52.5% for AC→WP+T, 53.2% (p=0.9) for AC→WP+L, and 62% (p=0.075) for AC→WP+TL. pCR percentages in the HR+ subset were 46.7%, 48% (p=0.85), and 55.6% (p=0.18), respectively, and were 65.5%, 60.6% (p=0.57), and 73% (p=0.37) in the HR- cohort. The corresponding pCR breast and nodes percentages were 49.1%, 47.4% (p=0.74), and 60.4% (p=0.04). Grade 3/4 toxicities include diarrhea in 2%, 20%, 27% (p&lt;0.001), and symptomatic Gr 3/4 left ventricular systolic dysfunction in 4%, 4%, and 2% (p=0.49). Conclusions: Substitution of lapatinib for trastuzumab in combination with the chemotherapy program employed in this study resulted in similar high percentages of pCR in both HR+ and HR- cohorts. Combined HER2-targeted therapy produced a numerically higher pCR percentage than single agent HER2-directed therapy, but the difference was not statistically significant. Central review of HER2 and ER is being conducted to determine if subsets benefiting from the combined HER2-targeted therapy can be identified. Funding: GlaxoSmithKline.
Intraperitoneal cisplatin and whole abdomen hyperthermia for relapsed ovarian carcinoma
Authors: E. L. Jones, L. R. Prosnitz, T. V. Samulski, J. Soper, A. Berchuck, D. Clarke-Pearson, M. W. Dewhirst, Z. Vujaskovic
Journal: Journal of Clinical Oncology (2004)

5038
Systemic Amyloidosis
Authors: Yoav C. Metzger, Deborah L. Cook, Todd E. Holmes
Journal: JAMA Dermatology (2019)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Dermatology HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Dermatology journal
Life-Threatening Complication after Right Renal Extracorporeal Shock Wave Lithotripsy: Large Hepatic Haematoma Requiring Embolisation of the Right Hepatic Artery: Part 2
Authors: Josef Beatrice, Raeto T. Strebel, Thomas Pfammatter, Jaime H. Röhweder, Tullio Sulser
Journal: European Urology (2007)
Subdural haematoma as a complication of spinal anaesthetic.
Authors: Gavin Andrews, Stephen Macmahon, Anne Austin, Donald Byrne
Journal: BMJ (1982)

pressures than those studied in the non-drug studies.The blood pressures before treatment of patients in the drug and non-drug studies were not significantly different (systolic blood pressure, t=0 69, df 98; diastolic blood pressure, t=0 43, df 109).In conclusion, we suggest that rather than see the outcome of our analysis primarily in terms of non-pharmacological treatments being shown to be less effective than drug treatments, the most important outcome is that several non-drug treatment modalities can be seen to have produced substantial and lasting reduction in blood pressure.These benefits are perhaps overall not as great as those of the drug studies, but are significantly greater than those of the placebo studies and are of appreciable clinical importance.We would certainly agree that many mildly hypertensive patients might be treated effec- tively by non-drug techniques, and indeed have concluded that: "Weight loss, progressive muscle relaxation, and yoga could provide competitive alternatives to step 1 drug treat- ment," and should be considered by the doctor.
More questions, not answers, emerge from Agent Orange studies
Authors: P. Gunby
Journal: JAMA (1983)

Exploration of the Agent Orange question, much like the war in Southeast Asia that spawned it, plods on in an atmosphere of unrealized expectations and unrelenting controversy. Essentially, the question is whether Agent Orange, a defoliant used by the United States to deny cover and crops to opposing forces in the Vietnam War, is responsible for any human health problems (<i>JAMA</i>[Medical News] 1980;243:2375-2379 and 1979;242:593-597, 241: 1443-1444). The two latest studies to be reported focused on possible Agent Orange-associated birth defects among veterans' offspring. Results obtained in the two studies were diametrically opposed, however. Additional recent developments include criticism (including some from the General Accounting Office) of seemingly ineffectual Veterans Administration (VA) attempts to address the Agent Orange health question, with the result that the VA is transferring a project to the Centers for Disease Control (CDC), Atlanta, and allegations that several chemical companies withheld information about potential health
The "murmur on top of the head" in acquired mitral insufficiency. Pathological and clinical significance
Authors: K. A. Merendino
Journal: JAMA (1967)

A "murmur on top of the head" has been documented in seven patients with mitral insufficiency. Five patients revealed ruptured chordae tendineae of anterior leaflets secondary to rheumatic fever or subacute bacterial endocarditis. Two remaining patients exhibited rheumatic valvulitis and annular dilatation. The regurgitation was readily corrected by excising or plicating the flail area or posteromedial annuloplasty, or both. Survivors are asymptomatic without embolization or infection. Whether due to ruptured chordae of the aortic leaflet (usual) or valvulitis and annular dilatation (and in the absence of valvular calcification by fluoroscopy), the problem has been correctable by iow-risk reconstructive procedures without need for prosthetic valve replacement. Therefore, when this murmur is present, valuable inferences regarding etiology, pathology, surgical therapy, and prognosis can be made.
Improving quality care through it/analytics for team-based care interventions.
Authors: Georgina T. Rodgers, Jacob Lindberg
Journal: Journal of Clinical Oncology (2019)

e18263 Background: Team based care is essential to achieve coordinated, high-quality care. We recognized a responsibility to identify new treatment patients to provided targeted, team based interventions. Previous attempts at identifying new patients were difficult, manual, and delayed. Our aim was to provide personnel with the appropriate means to identify new patients for services such as patient education, financial navigation, social work assessments and outreach calls for care coordination. As a result of multiple barriers and challenges, only 51% of our new patients were being identified. This project fit well in the larger context of the transformation of health care delivery through our participation in the Oncology Care Model, which places an emphasis on team based care. Methods: We used the Plan-Do-Study-Act continuous improvement model to develop an automated data set to identify new treatment patients across the oncology service line and leveraged our Information Technology (IT) Analytics team. A report was established based utilizing logic to identify the first appointment scheduled within the department and a secondary tab to look back at new patients within a three week time frame. Information is housed within a business intelligence software system that is easy for end users to see and understand. The initial report was validated for accuracy at an identification rate of 93% and the 3 week “look back” report gives the ability to identify the remaining patients. Results: We have seen marked improvements metrics as a result of the utilization of this report. Our Financial Navigators have been able to sustain out of pocket estimate calls at &gt; 94% YTD 2018. Social Work initial patient assessments have sustained at 79% for the last 6 months, and we have seen nearly 400 documented oncology patient education encounters each month. Identification of these patients allows us to target patient education, outreach, and psychosocial assessments at initiation of therapy. Care Coordinators are able to establish patient lists to track eligibility for survivorship at the appropriate time points. Conclusions: This project demonstrates the value of using IT/Data Analytics for continuous quality improvement projects related to patient centered team based care. The cross collaboration of stakeholders in data analysis should be explored as a mechanism to transform care through key services and interventions.
European Perspectives
Journal: Circulation (2009)

first encountered it as a medical student in 1982.The young Lefèvre was invited to visit a small catheterisation laboratory in the suburbs of Paris that started using PCI in 1981.It was an early venture for France, the first cases having only been carried out in 1980, and the country had just 10 to 15 catheterisation laboratories.By chance, the hospital where Lefèvre was a student was nearby."When I saw these cases, I was really impressed and excited, so I asked if I could go back," he recalls.The response was positive, so from then on, he went there once a week.After 6 months, he started to help with the procedures, and a few months later he had performed his first case.It was one of the happiest times in his career."At that time, it was very controversial because many people were saying that PCI is not working," he says.But he adds, "I was completely convinced that it would be the future because the results were very good despite the fact that it was in the early phase."These devices pale in comparison to those of today, but still Dr Lefèvre was sold on the idea that PCI would continue to develop and become a first-rate alternative to surgery.He began working in the field of interventional cardiology, and in 1984 he was invited to his first international interventional meeting in Geneva, which was organised by Bernhard Meier, MD.Professor Meier, who had a strong influence on Dr Lefèvre, had worked in Geneva and was a previous fellow of Andreas Gruentzig, MD, in Zurich when he was doing the first percutaneous coronary angioplasty cases."I was impressed by the quality of the organisation of the meeting, and also the quality of the discussion that we had," says Dr Lefèvre."I think it was because Bernhard Meier was completely open, so when there was a problem he did not try to hide it, but the opposite-to show the problem and to discuss and to explain how to solve it.I think it's a good way to learn.
Contempo: instrumented spinal fusions
Authors: C. Derian
Journal: JAMA (1994)

<h3>In Reply.</h3> —It is thoughtful of Dr Derian to update the medical community on important ongoing investigations apparently designed to demonstrate the safety and efficacy of spine instrumentation. If the phrase "increased caution" referrable to the use of spine instrumentation is not accurate, there is at least "increased scrutiny" being applied to such surgery. This scrutiny is taking place with regard to the volume of spine surgery currently being performed as well as the regulatory status of the instrumentation being used. Well-constructed, prospective, controlled studies are important to resolve these areas of concern, and I hope these will be appearing in the peer-reviewed literature in increasing numbers.
'Society's love affair with violence' cited as major factor in child abuse
Journal: JAMA (1984)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal