tbuckley/cabot-search huggingface dataset:
Whose Death Is It, Anyway
Authors: Elisabeth Hansot
Journal: Annals of Internal Medicine (1997)

Letters1 April 1997Whose Death Is It, AnywayElisabeth Hansot, PhD, Thomas A. Raffin, MD, and Timothy Gilligan, MDElisabeth Hansot, PhDStanford University, Stanford, CA 94305Brigham and Women's Hospital, Boston, MA 02115Search for more papers by this author, Thomas A. Raffin, MDStanford University, Stanford, CA 94305Brigham and Women's Hospital, Boston, MA 02115Search for more papers by this author, and Timothy Gilligan, MDStanford University, Stanford, CA 94305Brigham and Women's Hospital, Boston, MA 02115Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-126-7-199704010-00028 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:We appreciate the responses to our articles. We have received numerous testimonials from people who have had unfortunate experiences similar to Dr. Hansot's. Several of the preceding letters show the enormous difficulty patients and their families sometimes face when trying to have their wishes to limit care respected. Dr. Lena's account of a patient's family and friends having to become personally involved in extubating the patient must be disturbing to any physician. Dr. Ringel asks the key question, How do we prevent such unhappy scenarios in the future?First, physicians must accept the possibility that patients may not ...References1. Levinson W, Roter D. Physicians' psychosocial beliefs correlate with their patient communication skills. J Gen Intern Med. 1995; 10:375-9. Google Scholar2. Levinson W, Roter D. The effects of two continuing medical education programs on communication skills of practicing primary care physicians. J Gen Intern Med. 1993; 8:318-24. Google Scholar3. Feighny KM, Monaco M, Arnold L. Empathy training to improve physician–patient communication skills. Acad Med. 1995; 70:435-6. Google Scholar Author, Article, and Disclosure InformationAuthors: Elisabeth Hansot, PhD; Thomas A. Raffin, MD; Timothy Gilligan, MDAffiliations: Stanford University, Stanford, CA 94305Brigham and Women's Hospital, Boston, MA 02115 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 April 1997Volume 126, Issue 7Page: 588KeywordsCommunication in health careDecision makingForecastingHealth careLiving willsPatient advocacyPatientsPsychotherapy ePublished: 15 August 2000 Issue Published: 1 April 1997 Copyright & PermissionsCopyright © 1997 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Editorial Board
Authors: P Coates, Olivier Devuyst, Tilman Drueke, Paris Ckd, Jürgen Floege, Aachen Glomerulonephritis, Agnes Fogo, T Alp Ikizler, Jai Radhakrishnan, York Kir, Germaine Wong, Pierre Ronco, Brad Rovin, Detlef Schlöndorff, New York, Qais Al-Awqati, Saulo Klahr, St Louis, Thomas Andreoli, Little Rock, Roscoe Robinson, Durham Nephrology, Christina Wyatt, Vic Hasselblad, Jacksonville Zhezhen, Joseph Kim, Yi-Ju Li, , Durham, Dorothea Nitsch, London Ramakrishnan, Anupam Agarwal, Hans Anders, Jonathan Barratt, David Basile, Emmanuel Burdmann, São Paulo, Daniel Cattran, Christos Toronto, Yi-Pu Paris, Erik Chen, Steven Christensen, New Coca, Terence York, London Cook, D Vivette, New Agati, Farhad York, John Danesh, Andrew Daugirdas, Ian Davenport, Marc De Boer, Vikas Antwerp, St Dharnidharka, Kent Louis, Zheng Doi, Adriana Dong, Kai-Uwe Oviedo, Berlin Eckardt, Eiam-Ong Somchai, Michael Emmett, Dallas Endre, Sydney Evan, Pieter Evenepoel, Sarah Leuven, Denver Faubel, Fernando Faul, Rochester Fervenza, Danilo Mineola, Alessia Homburg, Barry Miami, Winston-Salem Freedman, Isehara Masafumi Fukagawa, Vesna Garg, Rochester Garovic, Laguna Glassock, Glenda Niguel, David Gobe, New Goldfarb, Matthew York, Mark Griffin, Angeles Haas, John Haase, Cijiang He, Michelle Hladunewich, Thomas Hostetter, Chi-Yuan Cleveland, San Hsu, Tobias Francisco, Benjamin Huber, St Humphreys, Reiko Louis, Jula Tokyo, Dallas Inrig, Francisco Kirsten Johansen, Roberto Kamyar Kalantar-Zadeh, Iowa Kalil, Yashpal City, Chicago Kanwar, New Kaskel, Krzysztof York, York Kiryluk, Clayton Kitching, Matthias Kopp, Ann Kretzler, Christian Arbor, Christophe Bonn, Paris Legendre, Los Lemley, Adeera Angeles, Philip Levin, Hong Li, Christoph Kong, John Toronto, Rochester Lieske, Jiannong Little, Kathleen Liu, San Liu, Youhua Francisco, Zhi-Hong Liu, Nanjing Liu, Dallas Lu, Matthias Berlin, Johannes Mack, Peter Mann, Hamilton Margetts, New Glen Markowitz, Ziad York, Kunihiro Paris, Rajnish Matsushita, Timothy Mehrotra, Palo Meyer, Jeffrey Alto, St Miner, William Louis, Houston Mitch, Jeremiah Moeller, St Morrissey, Rosa Louis, São Moysés, Rama Paulo, Peter Duarte, David Nelson, Clayton Nikolic-Paterson, Klaus Charlottesville, Juan Olgaard, York Oliver, Atlanta Charles O'neill, Mark Panzer, New Perazella, Janos Haven, Los Peti-Peterdi, Laura Angeles, Atlanta Plantinga, Didier Boston, Ambra Charlottesville, Susan Pozzi, Chicago Quaggin, Pia Maria, Milan Rastaldi, San Reeves, Heather Antonio, Jochen Reich, Giuseppe Reiser, Sharon Bergamo, Mariano Clayton, Mitchell Rodriguez, Michael Rosner, Robert Ross, Simone Safirstein, New Sanna-Cherchi, Antonio York, Kai Santoro, New Schmidt-Ott, Stephan York, Aarau Segerer, Sharma Kumar, La Jolla, Katalin Susztak, Tetsuhiro Tanaka, Tokyo Sydney, C Tang, Hong Kong, Ravi Thadhani, Joshua Boston, Jens Denver, Marcello Singapore, Frank Tonelli, Manjeri Van Der Sande, San Venkatachalam, Carsten Antonio, Joel Wagner, Ann Weinberg, Matthew Arbor, Donald Weir, Temple Wesson, Jack Westenfelder, Adam Wetzels, Myles Whaley-Connell, Keng-Thye Durham, Kwan-Dun Woo, Taiwan Wu, Yusuke Suzuki, Tokyo Zeisberg
Journal: Kidney International (2019)
Maternal Pulmonary Embolism by Amniotic Fluid
Authors: Paul E. Steiner
Journal: JAMA (1986)

While most of the deaths occurring during labor and in the early puerperium are said to be due to hemorrhage, toxemia, heart disease or other less common obstetric and medical causes, a few fatalities remain unexplained even after careful postmortem examination.<sup>1</sup>In the absence of pathologic chemical and anatomic changes such deaths are often considered, without proof, to be on a functional basis. It is the object of this paper to attempt to fill this gap in our knowledge and to point out that some of these obscure deaths form a disease entity with its characteristic causation, symptoms and pathologic changes by (<i>a</i>) presenting the clinical histories of 8 patients to show that they form a distinct group, (<i>b</i>) demonstrating in them a pathologic-anatomic basis for this series of symptoms and (<i>c</i>) demonstrating the experimental production of this disease in animals, the disease in them having a similar symptomatology
Harrison's Principles of Internal Medicine
Authors: John J. Massarelli
Journal: JAMA (1987)

Every three years there is a new edition of<i>Harrison's Principles of Internal Medicine</i>. This year's version, the 11th, lives up to expectations. Students unfamiliar with this book should be told that it is a 2118-page compendium of medicine written by 280 contributors, each an expert in his or her field. Part 1, the famous "Cardinal Manifestations of Disease," discusses alterations in various body systems and clinically pertinent symptoms and findings. The 80-page section on the nervous system deserves separate mention; it represents a masterful introduction to neurology. Part 2 deals with biologic considerations in the approach to clinical medicine, and part 3 treats infectious diseases and those due to environmental agents. Then follow ten more parts, each of which constitutes a different system. The orientation is pathophysiological and clinical throughout. Most physicians are familiar with one or more previous editions, and they require different information about this new one.
Air Toxics Regulatory Issues Facing Urban Settings
Authors: Kenneth Olden, Janet Guthrie
Journal: Environmental Health Perspectives (1996)

Biomarker research does not exist in isolation.Its usefulness can only be realized when it is translated into prevention strategies to protect public health.In the context of air toxics, these prevention strategies begin with the development of regulatory standards derived from risk assessment schemes.The Clean Air Act Amendments of 1990 list 189 air toxics, including many volatile organics, metals, and pesticides.The National Institute of Environmental Health Sciences (NIEHS), through its affiliation with the National Toxicology Program, has generated toxicity and carcinogenicity data on more than 100 of these air toxics.The NIEHS extramural and intramural research portfolios support a variety of projects that develop and validate biomarkers for use in environmental health science and risk assessment.Biomarkers have a tremendous potential in the areas of regulating air toxics and protecting public health.Risk assessors need data provided by biomarkers of exposure, biomarkers of dose/pharmacokinetics, biomarkers of susceptibility or individual variability, and biomarkers of effects.The greatest benefit would be realized if biomarkers could be employed in four areas of primary and secondary prevention.The first is the use of biomarkers to enhance extrapolation of animal data to human exposure situations in establishing risk standards.The second is the use of biomarkers that assess noncancer, as well as cancer, end points.Important health end points include pulmonary dysfunction, immunotoxicity, and neurotoxicity.Third, biomarkers that serve as early warning signs to detect intermediate effects would enhance our ability to design timely and cost-effective intervention strategies.Finally, biomarkers used to evaluate the effectiveness of intervention strategies, both in clinical and regulatory settings, would enable us to ensure that programs designed to protect public health do, in fact, achieve the desired outcome.
Empire Rheumatism Council: Twenty-fifth Annual Report
Authors: W Copeman, Mr Andrews
Journal: Annals of the Rheumatic Diseases (1962)

The chairman stated that the Council was able to look back over 25 years of hard work, an appro- priate stage at which to make a brief survey of progress.Here was a group of diseases-arthritis, fibrositis, gout-as old as mankind and probably more widespread and causing more suffering than any other complaint.Yet it was only in 1924 that the first report had been published about them by the Ministry of Health.The losses caused by these diseases revealed in that report shocked everyone, but still no action was taken.Rheumatism con- tinued to be regarded as an "act of God" for which there was no cure and little relief.That was the position until 1936, when a few medical men under the chairmanship of Sir William Willcox and later Lord Horder pledged themselves to do something, and their efforts resulted in the formation of the Empire Rheumatism Council.The first task was to survey the field before embarking upon a programme of research and two Travelling Fellows were appointed to sift and bring together all available scientific knowledge in Europe and America.In 1939 many activities had to be suspended, and it was not until 1946 that the Council was able to start work again.With less than £2,000 in the bank, there were suggestions that the Council should be wound up, but then came substantial offers of support, notably from Sir James Roberts.
Human milk as a bioindicator for body burden of PCDDs, PCDFs, organochlorine pesticides, and PCBs
Authors: P Fürst, C Fürst, K Wilmers
Journal: Environmental Health Perspectives (1994)

In the State Laboratory ofNorth Rhine-Westphalia for Food, hann ceuticalandEAnmnentalChemisry (Chemisches landesuntersucungsamt), more than 600 individual human milk samples have been analyzed for polychoated dibenzo- p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs), and more than 1400 individual milk samples have been analyzed for organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) since 1984.All samples were col- lected on a voluntary basis from nursing mothers mostly living in North Rhine VAstphalia, a federal state in Germany.The samples analyzed so far show a typical pattern of PCDDs and PCDFs.Out ofthe 210 possible congeners, only those with 2,3,7,8-chlorine substitution were found.While OCDD normally shows the highestconcentration, the levels ofthe other dioxin congeners decrease with decreasing number ofchlorine atoms.A different pattern was found for PCDFs.Within this group 2,3A,7,8-P5CDF is the most abundant congener, followed by the hexachlorodibenzofurans.The mean level of tetrachlorodibenzodiain (TCDD) was found to be of 3.2 pg/g on a fat basis and for total PCDDs and PCDFs, calculated as I-TEq (NATO/CMMS), 29.3 pg/g on a fat basis.The investiptions ofthe past 2years have revealed somewhat lower levels compared to former years.This might be an indication that the efforts undertaken tominimize dioxin emis- sions and to shut down known sources have already had an effect on the body burden ofhumans.Although mostly banned for a considerable period oftime now, some lipophilk ent dessuchas D , diekdrin, hhiorobemene (HCB), and hexachlorocyclohatanes (HCH) can still be found in human milk.However, the levels ofthese residueshave decreased during the past few years, indicating that the ban is having an effect.A similar trend was found for PCBs.Although their concentration in human milk was at the same level for a long period of time, a slight decrease was observed in the past 2 years.Although the tolerable daily intake concept, which is based on lifetime intake, should not be applied to the relative short nursing period, the results ofhuman milk analyses are far above these levels.Despite the fact that noadverse health effects in babies could definitely be related to date to background levels ofxenobiotics in human milk, it seems reasonable that all efforts should be undertaken to mniie the emission ofthese poltants and to shut down known sources to achieve a reduction of the body burden of humans.
LOCATION OF CONTAGIOUS DISEASE HOSPITALS.
Journal: JAMA (1894)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A decision analysis of surveillance for colorectal cancer in ulcerative colitis
Authors: F Delco
Journal: Gut (2000)

<h3>BACKGROUND</h3> Patients with long standing, extensive ulcerative colitis have an increased risk of developing colorectal cancer. <h3>AIMS</h3> To assess the feasibility of surveillance colonoscopy in preventing death from colorectal cancer. <h3>PATIENTS</h3> A hypothetical cohort of patients with chronic ulcerative colitis. <h3>METHODS</h3> The benefits of life years saved were weighted against the costs of biannual colonoscopy and proctocolectomy, and the terminal care of patients dying from colorectal cancer. Two separate Markov processes were modelled to compare the cost-benefit relation in patients with or without surveillance. The cumulative probability of developing colorectal cancer served as a threshold to determine which of the two management strategies is associated with a larger net benefit. <h3>RESULTS</h3> If the cumulative probability of colorectal cancer exceeds a threshold value of 27%, surveillance becomes more beneficial than no surveillance. The threshold is only slightly smaller than the actual cumulative cancer rate of 30%. Variations of the assumptions built into the model can raise the threshold above or lower it far below the actual rate. If several of the assumptions are varied jointly, even small changes can lead to extreme threshold values. <h3>CONCLUSIONS</h3> It is not possible to prove that frequent colonoscopies scheduled at regular intervals are an effective means to manage the increased risk of colorectal cancer associated with ulcerative colitis.
Norepinephrine
Authors: Pamela Ouyang
Journal: JAMA (1985)

As stated in the foreword to this book, catecholamines have played a remarkable role in the development of our general concept of neurotransmission. Norepinephrine is important in modulating the cardiovascular, endocrine, central, and peripheral nervous systems and blood pressure control in health and disease. This book should therefore be of interest to investigators and clinicians in a wide range of fields, including physiology, pharmacology, internal medicine, cardiology, critical care medicine, anesthesiology, and psychiatry. Drs Ziegler and Lake have brought together an international group of investigators and have produced a remarkable overview of this vast topic. I found the book well organized into sections dealing with the measurement, anatomy, physiology and function, and clinical aspects of norepinephrine, which allowed easy identification of topics of interest. The writing is generally clear. I appreciated the footnotes at the beginning of chapters 1, 5, and 6 allowing easy reference to the vast number of
Medical Education, Registration and Hospital Service
Journal: JAMA (1929)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Blood War
Authors: Jane O. Wayne
Journal: JAMA (2013)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
"Leukemia Houses"
Authors: ROBERT W. MILLER
Journal: Annals of Internal Medicine (1967)

Editorial Notes1 September 1967"Leukemia Houses"ROBERT W. MILLER, M.D., JOSEPH F. FRAUMENI JR., M.D., F.A.C.P.ROBERT W. MILLER, M.D.Search for more papers by this author, JOSEPH F. FRAUMENI JR., M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-67-3-674 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptRecently, a report (1) of leukemia among successive occupants of three houses in Kansas, Missouri, and Georgia has been widely publicized in the popular press. It is natural for the nonmedical reader, unaware of substantial research to the contrary, to conclude that leukemia is contagious. In consequence, leukemic persons and places may be feared and shunned, thus contributing unjustifiably to the distress of the patient and his family.The term "cancer houses" was apparently originated by Dr. Law Webb in 1892 (2). While in theory it is possible to determine whether the frequency of houses with multiple cases of cancer...References1. : Leukemia. Morbidity and Mortality Weekly Report 16: 167, (May 20) 1967. Google Scholar2. Cancer houses, in Imperial Cancer Research Fund 12th Annual Report, London, July 21, 1914, pp. 12-23. Google Scholar3. IDAFUKUHARAOHBA NAY: Several aspects of vertical transmission of Moloney virus. Nat. Cancer Inst. Monogr. 22: 287, 1966. MedlineGoogle Scholar4. MILLER RW: Radiation, chromosomes and viruses in the etiology of leukemia. Evidence from epidemiologic research. New Eng. J. Med. 271: 30, 1964. CrossrefMedlineGoogle Scholar5. FRAUMENIMILLER JFRW: Epidemiology of human leukemia: recent observations. J. Nat. Cancer Inst. 38: 593, 1967. MedlineGoogle Scholar6. MILHAM S: Leukemia in husbands and wives. Science 148: 98, 1965. CrossrefMedlineGoogle Scholar7. RANDALLREIQUAMGITHENSROBINSON DLCWJHA: Familial myeloproliferative disease. A new syndrome closely simulating myelogenous leukemia in childhood. Amer. J. Dis. Child. 110: 479, 1965. CrossrefMedlineGoogle Scholar8. HEATHMANNINGZELKOWITZ CWMDL: Case clusters in the occurrence of leukaemia and congenital malformations. Lancet 2: 136, 1964. CrossrefMedlineGoogle Scholar9. PIKEWILLIAMSWRIGHT MCEHB: Burkitt's tumour in the West Nile district of Uganda 1961-5. Brit. Med. J. 1: 395, 1967. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Epidemiology Branch National Cancer Institute National Institutes of Health Bethesda, Md. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByCopper (II)-catalyzed regio- and stereoselective addition of H/P(O)R2 to alkynesHistorisches, Definition, Klassifikation und Epidemiologie der LeukämienConnubial lymphoproliferative malignancies: A report of nine couplesBiomedical data resources: a limiting factor in analytic epidemiology. 1 September 1967Volume 67, Issue 3_Part_1Page: 674-676 Issue Published: 1 September 1967 PDF DownloadLoading ...