tbuckley/cabot-search huggingface dataset:
Clinical Report.
Journal: JAMA (1905)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Army Medical Service: Errata
Journal: BMJ (1900)

Hull on December 28th, at the age of 49.He had the misfortune to contract a chill before he had quite recovered from the effect of a second seizure of influenza, and upon this fol- lowed an attack of rheumatic fever, complicated towards the close with pneumonia.Although apparently a healthy man, he had evidently but little recuperative power, and, notwith- standing assiduous attention from medical friends, he gradually sank after less than a fortnight's confinement to bed.Mr. Thompson was in his early years a pupil of Sir Robert Martin Craven, and afterwards became a student at St. Bar- tholomew's Hospital.He obtained the diploma of M.R.C.S. and L.S.A. in 1871, and that of L.R.C.P.Lond. in I874.He held the office of House-Physician to St. Bartholomew's Hospital, and on his return to Hull was appointed House-Surgeon to the Hull Royal Infirmary.At a later date he was appointed Assistant Surgeon, and subsequently Surgeon to that Infirmary, where he did much good work.He was a skilful and accomplished surgeon, and in addition to his other many admirable qualities always displayed that stirling professional honesty which commands the respect and admiration of even the least friendly of acquaintances.Mr. Thompson was a member of the British Medical Association, and had held the office of President of the East York and North Lincoln
Registration, procurement, distribution, and use of misoprostol in Uganda: an interview-based observational study
Authors: Esther C Atukunda, Petra Brhlikova, Amon Ganafa Agaba, Allyson M Pollock
Journal: The Lancet Global Health (2013)

BackgroundPoor access to essential medicines remains a barrier to improvement of health in low-income countries. The maternal mortality rate from post-partum haemorrhage (PPH) in Uganda is one of the highest in the world. Uganda launched a misoprostol rollout programme for prevention of PPH in 2009, before WHO added it to the Essential Medicines List. We assessed the rollout programme in Uganda.MethodsWe reviewed relevant documents (WHO and Ministry of Health guidelines, registration dossier), interviewed key informants, and assessed procurement data collected from the Accessing Medicines in Africa and South Asia project (2010–13). We interviewed informants from purposively selected districts of Mbarara, Bundibugyo, Kampala, and Apac (one for each Ugandan Ministry of Health performance rank). We interviewed key informants about the introduction, registration, procurement, distribution, availability, and use of misoprostol, treatment guidelines, and human resources.FindingsWe interviewed 82 participants. Civil society organisations promote misoprostol rollout across Uganda as part of a larger assemblage of groups working on maternal health and had a key role in misoprostol registration with the National Drug Authority and development of clinical guidelines. Evidence-based requirements for registration, guideline development, and addition to the Essential Medicines List of Uganda were scarce. Civil society and national medical stores were procuring and distributing misoprostol to health centres 2 years before its inclusion in clinical guidelines and Uganda's Essential Medicines List, despite the contested evidence for its effectiveness. Promotion and distribution of misoprostol is continued by local affiliates offering incentives to private health-care providers promoting their programmes.InterpretationCivil society organisations accelerated misoprostol rollout in Uganda. Despite its introduction as a second choice treatment, evidence suggests an increasing trend of misoprostol procurement and availability over the medicine of choice—oxytocin. Absence of guidelines and lack of training precludes rational use of misoprostol and has ramifications for maternal care that need urgent evaluation.FundingEuropean Union.
Pharyngeal Gonorrhea-Reply
Authors: Virginia L. Rodriguez
Journal: JAMA (1982)

<h3>In Reply.—</h3> The active-duty population was swabbed with sterile cottontipped swabs in the pharynx. We used calcium alginate swabs for the urethral cultures in the active-duty population. We do not think this was a reason for the lower rates in the active-duty group. All cultures were directly plated onto the culture media and incubated promptly. We have no real explanation for the higher rates seen in the active-duty population. This may have arisen from a difference in the sexual practices in this group when compared with the prostitute population.
Re: Nicolas Mottet, Joaquim Bellmunt, Erik Briers, et al. EAU-ESTRO-ESUR-SIOG Guidelines on Prostate Cancer. European Association of Urology; 2017. http://uroweb.org/guideline/prostate-cancer
Authors: Juan Morote, Imma Comas, Jacques Planas
Journal: European Urology (2018)
JAMA Reference Directories. Organizations of medical interest
Journal: JAMA (1978)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Analysis of Breast Milk to Assess Exposure to Chlorinated Contaminants in Kazakhstan: Sources of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) Exposures in an Agricultural Region of Southern Kazakhstan
Authors: Kim Hooper, Tamara Chuvakova, Gulnara Kazbekova, Douglas Hayward, Asel Tulenova, Myrto X. Petreas, Timothy J. Wade, Kathleen Benedict, Ying-Yin Cheng, Jean Grassman
Journal: Environmental Health Perspectives (1999)

High levels of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD; up to 208 pg/g fat) were measured in samples of breast milk collected in 1997 from 64 donors [41 first-time mothers (primiparae)] living on state farms in southern Kazakhstan. TCDD was the major contributor (70%) to the toxic equivalents, matching the congener patterns found in breast milk and serum samples collected in 1994 and 1996 from donors in nearby villages. The highest TCDD levels were found in state farms adjacent to a reservoir (zone A), which receives agricultural runoff from cotton fields. TCDD levels in zone A were significantly higher than levels in a region more distant (zone B; &gt; 10 miles) from the reservoir (zone A: mean 53 pg/g, n = 17; zone B: mean 21 pg/g, n = 24; p = 0.0017). Levels of TCDD in breast milk and animal-derived foodstuffs were 10 times U.S. levels. Body burden and dietary data suggest that exposures to TCDD are chronic, environmental, and long term and may be related to the use of chemicals in cotton agriculture. The data suggest that the most likely source is the use of cotton defoliants contaminated with TCDD, and the most likely pathway for human exposure is via the consumption of contaminated foodstuffs.
Giant Ameloblastomas
Authors: V. Birch Rambo
Journal: JAMA (1977)

TUMORS of the jaw rarely go untreated for many years in the United States. This is not so in parts of Asia and Africa, where medical facilities are woefully inadequate and where folk medicine is practiced extensively. One of us (V. B. R.), as director of a 140-bed mission hospital in Central Africa, has treated two huge ameloblastomas during the past two years. They are reported because of their unusual size and their rarity in the Western world. <h3>Report of Cases</h3><h3>Case 1.—</h3> A man estimated to be 25 years old was admitted to the Good Shepherd Hospital (Hôpital du Bon Berger), Tshikaji, Kananga, Zaire, in May 1975. Progressive malnutrition had been noted at a mission food distribution center, and he had been persuaded to visit the mission hospital for treatment of a large tumor of the lower jaw that prevented chewing and made swallowing difficult (Fig 1). The patient
Salmonella
Journal: JAMA (2004)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression
Authors: Darrell D. Belke, Sandrine Betuing, Martin J. Tuttle, Christophe Graveleau, Martin E. Young, Mark Pham, Dongfang Zhang, Robert C. Cooksey, Donald A. McClain, Sheldon E. Litwin, Heinrich Taegtmeyer, David Severson, C. Ronald Kahn, E. Dale Abel
Journal: Journal of Clinical Investigation (2002)

To investigate the role of insulin signaling on postnatal cardiac development, physiology, and cardiac metabolism, we generated mice with a cardiomyocyte-selective insulin receptor knockout (CIRKO) using cre/loxP recombination. Hearts of CIRKO mice were reduced in size by 20–30% due to reduced cardiomyocyte size and had persistent expression of the fetal β-myosin heavy chain isoform. In CIRKO hearts, glucose transporter 1 (GLUT1) expression was reduced by about 50%, but there was a twofold increase in GLUT4 expression as well as increased rates of cardiac glucose uptake in vivo and increased glycolysis in isolated working hearts. Fatty acid oxidation rates were diminished as a result of reduced expression of enzymes that catalyze mitochondrial β-oxidation. Although basal rates of glucose oxidation were reduced, insulin unexpectedly stimulated glucose oxidation and glycogenolysis in CIRKO hearts. Cardiac performance in vivo and in isolated hearts was mildly impaired. Thus, insulin signaling plays an important developmental role in regulating postnatal cardiac size, myosin isoform expression, and the switching of cardiac substrate utilization from glucose to fatty acids. Insulin may also modulate cardiac myocyte metabolism through paracrine mechanisms by activating insulin receptors in other cell types within the heart.
Pulmonary Aspergillosis in a Child With Leukemia: Report of a Case and Brief Review of the Pediatric Literature
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
ABDOMINAL ARTERIOSCLEROSIS.
Journal: JAMA (1907)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Daily Intake of Copper from Drinking Water among Young Children in Sweden
Authors: Rolf Pettersson, Finn Rasmussen
Journal: Environmental Health Perspectives (1999)

Copper is an essential trace element that may cause intoxication if intake becomes excessive. Young children are at risk of intoxication because of high consumption of drinking water and immature copper metabolism. The aims of this prospective study were to estimate concentrations of copper in drinking water, volumes of drinking water consumed by children, and children's daily intake of copper. Concentrations of copper in unflushed drinking water were analyzed for 1,178 children living in Uppsala and Malmö, Sweden, and concentrations and amounts of copper consumed from drinking water were estimated for 430 of these children, 9-21 months of age. The study children were from Swedish families, were not enrolled in publicly provided day care, and were not breast-fed more than three times a day. In the initial population, the 10th percentile for copper concentration in unflushed drinking water was 0.17 mg/L, the median was 0.72 mg/L, and the 90th percentile was 2.11 mg/L. In the subpopulation of 430 children, the 10th percentile for daily intake of copper from drinking water was 0.03 mg/L, the median was 0.32 mg/L, and the 90th percentile was 1.07 mg/L. The median daily intake of copper from drinking water was higher in Uppsala, at 0.46 mg, than in Malmö, at 0.26 mg. For groups of children whose families took part in a later prospective diary study, the copper concentration in consumed water could, to some extent, be predicted from the concentration of copper in unflushed drinking water. The lowest concentrations of copper in drinking water were found in households with old water-pipe systems and in those living in detached houses. A large proportion of the young children satisfied their daily requirement of copper solely from drinking water. About 10% of the children had a copper intake above the level recommended by the World Health Organization.
JAMA Reference Directories
Journal: JAMA (1967)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Marriages
Journal: JAMA (1933)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Eccrine Poroma
Authors: Jatin P. Shah
Journal: JAMA (1970)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Expression of the Constitutive and Inducible Forms of Heat Shock Protein 70 in Human Proximal Tubule Cells Exposed to Heat, Sodium Arsenite, and CdCl 2
Authors: Seema Somji, John H. Todd, Mary Ann Sens, Scott H. Garrett, Donald A. Sens
Journal: Environmental Health Perspectives (1999)

We determined the expression of the constitutive (hsc 70) and inducible (hsp 70) forms of heat shock protein 70 mRNA and protein in human proximal tubule (HP]) cells exposed to letal and sublthal concentrations of Cd+2 under both acute and etded conditions of exposure.The HPT cells exhibited the dassic heat shock response when subjected to a physical (heat) or chemical stress (sodium arsenite); hsc 70 mRNA and protein levels were constant or slighty incas, whereas hsp 70 mRNA and protein were greatly elevated.Acute exposure to 53.4 pM.CdC½ for 4 hr failed to increase either hsc 70 mRNA or protein, a finding similar to that observed under classic conditions of stress.However, under identical conditions of acute exosure to Cd2, the expcted increase in hsp 70 protein level was suppressed as compared to that found under cassic conditions of physical or chemical stress.The decrease in hsp 70 protein level correlated to the reduced expression of mRNA from the 4s 70Bgene.The expression of mRNA from the 4sp 70A and 4sp 70Cgenes was similar to that found when the cells were treated with heat shock or sodium arsenite.We modeled an exended exposure to Cd2J by treating the cells continuously with Cd2P at both lethal and sub- lethdl levels over a 16-day time course.Chronic exposure to Cd2W failed to increase either hsc 70 mRNA or protein levels in the HPT ce}ls at a nonlethal dosage level and decreased hsc 70 mRNA and protein levels late in the time course oflethal exposure.Under identical conditions, the expression ofhsp 70 protein remained at basal levels that were only marginally detectable roughout the time course.Hsp 70A and hsp 70C miRNA levels were unaltered by extended exposure to CP, and hsp 70B mRNA was not detected during the 16-day time course.Cd2 is a poor inducer of hsc 70 and hsp 70 in the proximal tubule under both acute and long-term exposure.These results reinforce the fact that the expression of lsp 70 protein does not result from the transcription of a single gene, but is derived from what may be a complex interplay of several underlying genes.