tbuckley/cabot-search huggingface dataset:
Typhoid fever causing massive lower gastrointestinal hemorrhage. A reminder of things past
Authors: R. W. Strate
Journal: JAMA (1976)

AT THE turn of the 20th century, the treatment of typhoid fever was the major activity of many physicians. Although it is seldom seen in the United States today (approximately 400 cases per year<sup>1</sup>), this disease must be kept in mind as a rare cause of gastrointestinal bleeding. The diagnosis of typhoid fever should especially be considered in visitors or recent immigrants from foreign countries who have a toxic illness. <h3>Report of a Case</h3> A 17-year-old youth, a recent immigrant from northern Mexico, came to the hospital after passing several clots of bright red blood per rectum. He had had a two-week history of anorexia, weakness, myalgia, arthralgia, night sweats, and recent vomiting. There had been no history of diarrhea. On arrival at the hospital he was acutely ill, with a temperature of 39.7 C; blood pressure, 110/70 mm Hg; pulse rate, 108 beats per minute; and respiration rate,
Establishment of a cell line from a hepatocellular carcinoma from a patient with hemochromatosis
Authors: G SING
Journal: Hepatology (1994)

We describe the establishment and characterization of a novel hepatoma cell line. This cell line, designated RBHF-1, was established from a hepatocellular carcinoma of a 67-yr-old man with a history of genetic hemochromatosis. At this writing, the cells have been maintained in RPMI-1640 tissue-culture medium and fetal calf serum without any additional supplements for 30 mo. The cells form colonies on soft agar and are not tumorigenic in nude mice. The cell line is polymorphic and displays characteristics of mature hepatocytes by synthesizing albumin, α2-macroglobulin, fibronectin and α-fetoprotein. Cytogenetic analysis shows multiple chromosomal aberrations, with a consistent deletion in the long arm and deletions or rearrangements in the short arm of chromosome 1. There is no evidence for hepatitis B or hepatitis C virus infection of the cell line. The cells contain no detectable intracellular iron after staining with Perls' stain. Unlike other hepatoma cell lines, there is no detectable binding of epidermal growth factor to RBHF-1 cells. This is the first cell line to be established from a patient with hemochromatosis, and it provides a potentially important model for the study of hepatocyte transformation in association with iron overload. (Hepatology 1994;20:74–81.)
Cabozantinib Approved for Rare Thyroid Cancer
Journal: Cancer Discovery (2012)

Abstract Cabozantinib (Cometriq; Exelixis) has been approved by the U.S. Food and Drug Administration for the treatment of progressive, metastatic medullary thyroid cancer. Separately, in a phase II study, the drug showed antitumor activity in men with metastatic, castration-resistant prostate cancer.
Incorrect Information
Journal: JAMA (2019)

Ablation vs Medical Therapy on Quality of Life Among Patients With Atrial Fibrillation: The CABANA Randomized Clinical Trial," 1 published in the April 2, 2019, issue of JAMA, had an error in the Results section, which incorrectly stated that a higher Atrial Fibrillation Effect on Quality of Life score indicates a higher level of atrial fibrillation-related disability.The Results have been corrected and now state that a higher Atrial Fibrillation Effect on Quality of Life score indicates a lower level of atrial fibrillation-related disability.(All other information in the Results was correct and is unchanged.)This article was corrected online.
Radiorenocystogram in Chronic Pyelonephritis
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Patients' Reports of Counseling on Mammography Screening by Health-Care Providers—North Carolina, 1997
Journal: JAMA (1999)

Regular mammography screening combined with timely and appropriate treatment can reduce mortality from breast cancer by 30% in women aged 50-69 years and 16% in women aged 40-49 years. A physician's recommendation has been strongly associated with a patient having a mammogram. This report analyzes data collected during 1997 in North Carolina as part of the Behavioral Risk Factor Surveillance System (BRFSS), which indicated that 23% of women aged > or =40 years who had had a routine physical examination during the 2 years preceding the survey did not recall having a discussion about mammography with a health-care provider.
Cetrimide allergy presenting as suspected non-accidental injury
Authors: J. K Inman
Journal: BMJ (1982)

Cetrimide allergy presenting as suspected non-accidental injurySuspected non-accidental injury is becoming a more frequent paediatric diagnosis in Britain.I describe a case of presumed non-accidental injury that proved to be an allergic response to cetrimide (12% solution), a commonly prescribed preparation.Case report
'Rip van Winkle period' ends for puerperal psychiatric problems
Authors: T. Ziporyn
Journal: JAMA (1984)

A young woman gave birth to her first infant in a fairly routine delivery but five days later started having delusions, hallucinations, and nightmares. Soon afterward, she grew extremely depressed. Days passed, and delirium alternated with depression, accompanied by weakness, excessive sweating, and, weeks later, menstrual irregularities. To the relief of her perplexed physician, however, after several months this new mother suddenly recovered, completely resuming all normal activities. That happened in 1858. If it had happened today— and similar scenarios do—the obstetrician might well have referred the woman to a psychiatrist. Although the French physician Louis V. Marcé wrote a treatise on madness after childbirth in 1858, and physicians since Hippocrates have noted similar behavior, official medical recognition of specifically puerperal psychiatric problems went into the deep freeze years ago, and only now have some psychiatrists begun thawing it out. "For three quarters of the 20th century, psychiatrists lay down
Reversed Arrows in Figure 2
Journal: JAMA Network Open (2019)

Forecasted Posttraumatic Stress Symptoms, and Psychological Responses Before and After an Approaching Hurricane," 1 2 arrows in Figure 2 were reversed on initial publication.The arrow between "Irma-related media exposure" and "Wave 2 adjustment," as well as the arrow between "Degree of hurricane exposure" and "Wave 2 adjustment," were previously pointing away from "Wave 2 adjustment" and are now pointing toward.This article has been corrected online.
MISCELLANEA MEDICA
Journal: JAMA (1983)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
RURAL MEDICAL SERVICE IN AMERICA
Journal: JAMA (1923)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Workshops on Starting or Joining a Practice
Journal: JAMA (1990)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Case 37-2011: A 9-Month-Old Boy with Recurrent Tachypnea and Respiratory Distress
Journal: New England Journal of Medicine (2012)

Next to NothingWhat comes next, you ask As I turn to keep you facing away While your neighbor collects The toothbrush and the shoes And the clothes prefolded After dressing for the last struggle In that room where the monitor is now dark With no line left.
Who Should Do Psychotherapy?
Journal: BMJ (1970)

MDICJOUL 227 also been examined.This has a differently designed blood port gasket, and we found that although this is a loose gasket system bacteria tend to collect and survive beneath the blood port gasket in considerable numbers.This gasket was much more difficult to remove than the other type and was probably not-removed so regularly when the boards were disinfected.The use of loose gaskets has largely removed the sequestration of bacteria in the gasket channels.Thus there is a reduction in the bacterial challenge to the disinfection techniques, and, as these techniques will always suffer from the possibility of incomplete access of disinfectant either to the dismantled boards or to the assembled dialyser, there follows an improvement in the bacteriological state of the prepared dialyser and a reduction in the likelihood of bacterial proliferation during the subsequent dialysis.
The problem-oriented record. A two-column modification
Authors: M. D. Aronson
Journal: JAMA (1973)

A two-column modification of the problem-oriented record is presented that (1) provides one way to reduce the large amount of data collected on an average hospitalized patient, (2) can function as an effective teaching and auditing tool by providing immediate feedback to the intern or student on his workup, (3) can reduce the time outlay of residents by eliminating the need to repeat written histories and physicals, and (4) can serve as a tool to more carefully audit a resident's contributions, satisfying the recent requirements of the Board of Internal Medicine.
Book Review Clinical Nutrition and Feeding in Infancy and Childhood . By I. Newton Kugelmass, M.D., Ph.D., Sc.D., Associate Attending Pediatrician, Fifth Avenue Hospital; Riverside Hospital; Pediatrist, Hospital for Ruptured and Crippled; Director, Heckscher Institute for Child Health. Published by J. B. Lippincott Co. Price $6.00.
Journal: New England Journal of Medicine (1930)
CASE OF PURPURA FULMINANS
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Syndrome of Congenital Aortic Stenosis in Infancy
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Leads from the MMWR. Quarterly report to the Domestic Policy Council on the prevalence and rate of spread of HIV and AIDS in the United States
Journal: JAMA (1988)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
FOREIGN CORRESPONDENCE. LETTER FROM LONDON
Journal: JAMA (1989)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract B1-60: Predicting drug response by profiling the epigenome: Super-enhancers as biomarkers
Authors: David A. Orlando, Michael R. McKeown, Mei Wei Chen, Cindy Collins, Matthew G. Guenther, Christian C. Fritz
Journal: Cancer Research (2015)

Abstract Identifying biomarkers that predict clinical responses to anticancer therapies is an important challenge in oncology. A desirable biomarker is a cell-identifying feature that can distinguish between drug responsive and unresponsive cell types. Most of the best studied biomarkers are gene mutations or copy-number changes, where the genomic alteration is the key defining feature. However, not all differences in clinical responses can be attributed to genetic differences. Therefore, it is critical that we identify other cellular features that can predict response. A recently described epigenomic feature, termed super-enhancer (SE), defines key cell identity and disease genes and SEs are effectors of initiating and maintaining cell type-specific gene expression programs. In this work we generate super-enhancer maps across multiple cancer cell lines and connect those maps to response to different drug treatments. We show that super-enhancers can be used as biomarkers to predict response to drugs across multiple cell-line models of cancer. This work suggests that interrogating epigenomic features, and in particular super-enhancers, can be a powerful biomarker discovery platform and can enable rational patient selection and therapeutic strategies. Citation Format: David A. Orlando, Michael R. McKeown, Mei Wei Chen, Cindy Collins, Matthew G. Guenther, Christian C. Fritz. Predicting drug response by profiling the epigenome: Super-enhancers as biomarkers. [abstract]. In: Proceedings of the AACR Special Conference on Computational and Systems Biology of Cancer; Feb 8-11 2015; San Francisco, CA. Philadelphia (PA): AACR; Cancer Res 2015;75(22 Suppl 2):Abstract nr B1-60.
Massive hepatic necrosis in a patient receiving allopurinol
Authors: R. C. Butler
Journal: JAMA (1977)

ALLOPURINOL (4-hydroxypyrazolo [3, 4-<i>d</i>] pyrimidine) (Zyloprim) has been used since 1962 in the treatment of hyperuricemia. Numerous side effects have been noted. Gastrointestinal distress, diarrhea, pruritus, maculopapular rash, headache, fever, leukopenia, and eosinophilia have been reported, as have reversible alterations in liver function tests with or without jaundice. The more serious complications of xanthine stones, fatal toxic epidermal necrolysis, and acute vasculitis, and granulomatous hepatitis<sup>1</sup>have also been reported. Hepatitis of mild to moderate severity has been described in patients who had severe allopurinol hypersensitivity.<sup>2,3</sup>We report a fatal outcome of acute, massive, hepatic necrosis in a patient receiving allopurinol for asymptomatic hyperuricemia. <h3>Report of a Case</h3> A 48-year-old woman had been under medical care since 1965 for hypertension, with blood pressure readings up to 240/150 mm Hg. She had had slowly progressive retinopathy and hypertensive cardiovascular disease manifested by congestive heart failure. She was admitted to
Environmental Health
Journal: JAMA (1998)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal