tbuckley/cabot-search huggingface dataset:
Dissolution of bilateral uric acid calculi causing anuria
Authors: A. A. Eason
Journal: JAMA (1978)

THE NONSURGICAL therapeutic approach to anuria caused by obstructive uric acid calculi has been advocated for poor-risk patients.<sup>1</sup>We recently used this method of treatment for a similar problem, which was successfully resolved by administration of allopurinol, alkalinization of the urine, and catheter irrigation of the renal pelvis with sodium bicarbonate solution. <h3>Report of a Case</h3> A 42-year-old man with left flank pain, nausea, vomiting, and hematuria was examined in the emergency ward. Excretory urography disclosed a questionable filling defect in the right renal pelvis and delayed function on the left side. At three hours into the pyelographic study, the left flank pain suddenly disappeared, and a film showed mild caliectasis and contrast medium now passing through an undilated left ureter. The patient was asymptomatic when discharged, but came back six days later, again complaining of flank pain with intractable nausea and vomiting. He indicated no previous history of
A CLINICAL STUDY OF EPITHELIOMA OF THE LOWER LIP
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Putting a better cap on the cervix
Authors: G. McBride
Journal: JAMA (1980)

It makes a lot of sense when you think about it. Who could appreciate the concept of exact fit more than a dentist? So the dentist designs caps for cervices instead of teeth. What of it? The experimental caps, designed to be worn continuously (unlike other cervical caps), seem to be working well now, although there were problems with materials and design at first. This unusual saga began about 3 1/2 years ago when Robert A. Goepp, DDS, PhD, encountered his old friend, obstetrician-gynecologist Ewe Freese, MD, at the institution where both were on the faculty—the University of Chicago. In the casual what's-new-in-your-department conversation that ensued, Freese lamented the lack of effective but safe contraceptive methods. Goepp asked why cervical caps could not serve this purpose. Freese said that the older, presized caps have problems, among them the fact that they can easily become dislodged. Goepp responded that the caps
Neurology
Authors: Robert J. Joynt
Journal: JAMA (1992)

Interest in neurology and neuroscience continues to mount as new research unveils more of the basic changes underlying neurological disorders. Advances in prevention, diagnosis, and treatment of neurological disease will depend on elucidation of their pathology on a genetic, molecular, and cellular level. An example of treatment arising from fundamental knowledge about disease mechanisms is enzyme replacement therapy in Gaucher's disease. Gaucher's disease is caused by a deficiency of the enzyme glucocerebrosidase, with consequent accumulation of glucocerebrosides in macrophages. It results in a gradual enlargement of visceral organs, replacement of bone marrow, and, in some persons, progressive neurological deterioration. The progression of the disease was beneficially altered by the infusion of macrophage-targeted glucocerebrosidase in 12 patients.<sup>1</sup>Organ enlargement was reversed, anemia was corrected, and energy was improved. Similar approaches may be beneficial in other enzyme-deficiency disorders. The issue of treatment for carotid stenosis has been controversial. A large, multicenter
THE PROGNOSTIC IMPORTANCE OF THE APPEARANCE OF EYE LESIONS IN INTERSTITIAL NEPHRITIS.
Journal: JAMA (1898)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Alcoholic Hepatitis
Authors: Stanford Wessler
Journal: JAMA (1968)

Dr. Harvey M. Goldstein<sup>*</sup>: A 38-year-old Negro man with a 20-year history of heavy alcohol ingestion was initially hospitalized on the Washington University Service at St. Louis City Hospital in January 1967 for evaluation of bilateral leg pain, numbness, and paresthesias. The liver was massively enlarged, and liver function tests were consistent with hepatocellular destruction. He responded to dietary and vitamin therapy and was finally discharged, with a return of liver function toward normal. One day prior to the present admission on May 27, 1967, he noted the onset of abdominal swelling, tightness, and vague upperabdominal pains. He denied nausea and vomiting, but in the two weeks prior to admission, he had four to five diarrheal stools per day and a 9.1-kg (20-lb) weight loss. Physical examination revealed a young Negro male in no acute distress but with marked abdominal distention. Pulse rate was 100 beats per minute and regular;
Anesthesiology
Journal: JAMA (2002)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abuse of pregnant women and adverse birth outcome. Current knowledge and implications for practice
Authors: E H Newberger, S E Barkan, E S Lieberman, M C McCormick, K Yllo, L T Gary, S Schechter
Journal: JAMA (1992)

ABUSE of pregnant women is not rare. The prevalence of physical assault of women during pregnancy has been estimated at 8% in a random sample drawn from public and private prenatal clinics,<sup>1</sup>and between 7% and 11% in nonrandom samples drawn from university obstetric clinic services.<sup>2,3</sup>Rates of overall violence against pregnant women gathered by the Second National Family Violence Survey<sup>4</sup>were as follows: 154 acts of violence per 1000 during the first 4 months of pregnancy and 170 acts of violence per 1000 women during the fifth through ninth months. (Pregnant women's risk of what was characterized as "abusive violence" was 60.6% greater than that of nonpregnant women in this national probability sample of 6002 households, but this was interpreted as an artifact of age because women under 25 years of age were more likely both to be pregnant and to be abused by husbands and
A Thousand Out-Patients
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Effects of varying doses of spironolactone without and with nitrates on portal vein pressure and kidney function in partial portal vein ligated rats
Authors: M Van de Castelle
Journal: Hepatology (1996)

The optimal dose of spironolactone to reduce portal vein pressure, alone or in combination with isosorbide-5-mononitrate (IsMn), has not been identified. We studied the effects of 8 days oral treatment with spironolactone, IsMn or both on portal pressure, plasma volume and renal sodium handling in rats with partial portal vein ligation. At daily doses of 0.33; 0.50; 1, and 1.50 mg/kg, spironolactone reduced portal pressure (all P < .05) as compared with placebo. Only the highest dose significantly lowered plasma volume (10.1 ± 0.7 vs. 13.0 ± 0.3 mL; P < .03) and enhanced urinary fractional sodium excretion (0.73 ± 0.04 vs. 0.58 ± 0.03%; P < .03) and the (Na+)/(K+) ratio in urine (0.43 ± 0.04 vs. 0.30 ± 0.03; P < .02). IsMn at doses of 0.25; 0.50, and 1 mg/kg decreased portal pressure (all P < .05) without a change in plasma volume but with a tendency (not significant) to lower fractional sodium excretion. IsMn impaired free water clearance at doses of 0.5 and 1 mg/kg (P < .05). Combinations of spironolactone 1 mg/kg with IsMn 0.5 or 1 mg/kg have no additive effect on portal pressure compared with spironolactone or IsMn alone. The higher the dose of IsMn in the combination, the more the natriuretic effect of spironolactone is opposed. Low doses of spironolactone are as effective as a higher dose to reduce portal pressure. This reduced portal pressure was independent of changes in plasma volume and diuretic effect, which suggests that spironolactone might have a direct vasoactive effect on the splanchnic circulation. To counteract sodium retention of nitrovasodilators, combination with high doses of spironolactone seems advantageous.
American medicine's problems, opportunities, and enemies
Authors: G. D. Lundberg
Journal: JAMA (1988)

In a recent issue ofTHE JOURNAL, I wrote, "In developed countries, the Golden Age of Medicine is at hand—for the patients."<sup>1</sup>While it is evident that our resources and our accomplishments are truly extraordinary, we are far away from having achieved any kind of medical utopia. This editorial attempts to identify some of the myriad reasons hindering realization of that distant ideal and suggests proper responses. See also p 3171. There are three basic ways to manage any enterprise. One is by strategic planning, setting goals and objectives, identifying the resources needed to address them, and then proceeding with iteration and accountability. Another approach is to identify and analyze problems as they arise, set priorities, and logically set about solving the problems. A third and less desirable (albeit commonplace) way is simply to muddle through, defending the status quo against change until change becomes mandatory. Applying a strategic
MEETING OF THE WORLD MEDICAL ASSOCIATION
Journal: JAMA (1952)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Why Wine?
Journal: JAMA (1995)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Alcohol Involvement in Fatal Motor-Vehicle Crashes—United States, 1997-1998
Journal: JAMA (2000)

The following table compares alcohol involvement in fatal motor-vehicle crashes by age group and blood alcohol concentration (BAC) levels for 1999 and 2000. A fatal crash is considered alcohol-related by the National Highway Traffic Safety Administration (NHTSA) if either a driver or nonoccupant (e.g., pedestrian) had a BAC of > or =0.01 g/dL in a police-reported traffic crash. Because BACs are not available for all persons in fatal crashes, NHTSA estimates the number of alcohol-related traffic fatalities on the basis of a discriminant analysis of information from all cases for which driver or nonoccupant BAC data are available.
Pyruvate and Lactate Excretion in Diabetes Mellitus and Benign Glycosuria
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Permissive hypercapnia in acute respiratory failure
Authors: A. Bidani
Journal: JAMA (1994)

<h3>Objective.</h3> —To evaluate the potential efficacy of pressure limitation with permissive hypercapnia in the treatment of acute respiratory failure/adult respiratory distress syndrome on the basis of current theories of ventilator-induced lung injury, potential complications of systemic hypercarbia, and available human outcome studies. <h3>Data Sources.</h3> —Articles were identified through MEDLINE, reference citations of published data, and consultation with authorities in their respective fields. <h3>Study Selection.</h3> —Animal model experimentation and human clinical trials were selected on the basis of whether they addressed the questions of pressure limitation with or without hypercapnia, the pathophysiologic effects of hypercapnia, or the concept of ventilator-induced parenchymal lung injury. Frequently cited references were preferentially included. <h3>Data Extraction.</h3> —Data were analyzed with particular emphasis on obtaining the following variables from the clinical studies: peak inspiratory pressures, tidal volumes, minute ventilation, and Pco<sub>2</sub>. Quantitative aspects of respiratory physiology were used to analyze the theoretical effects of permissive hypercapnia on ventilatory requirements in normal and injured lungs. <h3>Data Synthesis.</h3> —Extensive animal model data support the hypothesis that ventilator-driven alveolar overdistention can induce significant parenchymal lung injury. The heterogeneous nature of lung injury in adult respiratory distress syndrome, with its small physiologic lung volume, may render the lung susceptible to this type of injury through the use of conventional tidal volumes (10 to 15 mL/kg). Permissive hypercapnia is an approach whereby alveolar overdistention is minimized through either pressure or volume limitation, and the potential deleterious consequences of respiratory acidosis are accepted. Uncontrolled human trials of explicit or implicit permissive hypercapnia have demonstrated improved survival in comparison with models of predictive mortality. <h3>Conclusions.</h3> —Avoidance of alveolar overdistention through pressure or volume limitation has significant support based on animal models and computer simulation. Deleterious effects of the associated hypercarbia in severe lung injury do not appear to be a significant limiting factor in preliminary human clinical trials. Although current uncontrolled studies suggest benefit, controlled trials are urgently needed to confirm these findings before adoption of the treatment can be endorsed. (<i>JAMA</i>. 1994;272:957-962)
Mixed-histologic-type submucosal invasive gastric cancer as a risk factor for lymph node metastasis: feasibility of endoscopic submucosal dissection
Authors: N. Hanaoka, S. Tanabe, T. Mikami, I. Okayasu, K. Saigenji
Journal: Endoscopy (2009)

Correction to: Mixed-histologic-type submucosal invasive gastric cancer as a risk factor for lymph node metastasis: feasibility of endoscopic submucosal dissectionEndoscopy 2009; 41(05): 427-432DOI: 10.1055/s-0029-1214495
SECTION MEETINGS OF THE ASSOCIATION.
Journal: JAMA (1891)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Cytology of In Situ Carcinoma of the Human Urinary Bladder
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal