tbuckley/cabot-search huggingface dataset:
<i>QuickStats</i>: Percentage* of Adults Who Ever Used an E-cigarette† and Percentage Who Currently Use E-cigarettes,§ by Age Group — National Health Interview Survey, United States, 2016¶
Journal: MMWR Morbidity and Mortality Weekly Report (2017)

44 45-64 ≥65 Ever used an e-cigarette Currently use e-cigarettes Percentage Age group (yrs) * With 95% confidence intervals indicated with error bars.† Based on the response of "yes" to the survey question "Have you ever used an e-cigarette, even one time?"§ Based on a response of "every day" or "some days" to the question "Do you now use e-cigarettes every day, some days or not at all?" ¶ Estimates are based on household interviews of a sample of the civilian, noninstitutionalized U.S. population and are derived from the National Health Interview Survey Sample Adult component.Overall, 15.4% of adults aged ≥18 years had ever used an e-cigarette, and 3.2% currently used e-cigarettes in 2016.Adults aged 18-24 years were the most likely to have ever used an e-cigarette (23.5%); the percentage declined steadily to 4.5% among adults aged ≥65 years.Adults aged 18-24 years (4.5%) and 25-44 years (4.2%) were more likely to be current e-cigarette users than adults aged 45-64 years (2.9%) and those aged ≥65 years (1.0%).Across all age groups, fewer than one fourth of adults who had ever used an e-cigarette reported being a current user.
Abstract 16743: A Kinase Interacting Protein 1 Does Not Protect From Adverse Cardiac Remodelling but Attenuates Myocardial Ischemia - Reperfusion Injury
Authors: Harmen G Booij, Hongjuan Yu, Rudolf A de Boer, Wiek H van Gilst, Herman H Silljé, B D Westenbrink
Journal: Circulation (2015)

Introduction: A kinase interacting protein 1 (AKIP1) attenuates myocardial ischemia / reperfusion (I/R) injury and stimulates beneficial cardiac remodeling in cultured cardiomyocytes. Whether these findings translate into functional benefits in vivo remains to be established. Hypothesis: We assessed the hypothesis that cardiac overexpression of AKIP1 attenuates myocardial heart failure development or I/R-injury in mice. Methods: We created transgenic mice with cardiac-specific overexpression of AKIP1 (AKIP1-TG). First, AKIP1-TG mice or their wild type littermates were subjected to transverse aortic constriction (TAC) and myocardial infarction (MI) with permanent ligation of the left coronary artery. Second, infarct size after 45 minutes ischemia followed by 24h reperfusion was assessed with Evans Bleu and triphenyltetrazolium chloride staining. Results: AKIP1-TG mice and wild type littermates displayed similar left ventricular remodeling and function after TAC or MI as measured with magnetic resonance imaging. Histological indices of heart failure severity, including cardiomyocyte cross-sectional area, capillary density and fibrosis were also similar. However, infarct size relative to the area at risk was reduced 2-fold in AKIP1-TG mice after I/R (15% ± 3 vs. 29± 4 %, p&lt;0,05) and accompanied with a marked reduction in apoptosis (5,4 ± 0,5% vs. 8,1 ± 1,1%, p&lt;0,05). AKIP1 overexpression did not influence cardiac transcription or signaling. Subcellular fraction studies showed enrichment of AKIP1 in mitochondria. In addition, AKIP1 attenuated calcium induced swelling of mitochondria (0.77 ± 0.01 vs. 0.71 ± 0.01, p&lt;0.05), suggesting a direct role for AKIP1 in the mitochondrial permeability transition pore. Conclusions: In conclusion, AKIP1 does not influence cardiac remodeling in models of chronic heart failure. However, AKIP1 does attenuate myocardial I/R injury through stabilization of the mitochondrial permeability transition pore.
Time to Spare Newly Diagnosed Non Transplant Eligible Myeloma (eNDMM) from Thalidomide
Authors: Hélène Demarquette, Stéphanie Guidez, Artur J. Jurczyszyn, Denis Caillot, Brigitte Pegourie, Marie Lorraine Chretien, Charles Lancesseur, Lionel Karlin, Cristina M. Joao, Claire Bories, Laurence Legros, Laurent Garderet, Souhila Ikhlef, Martine Escoffre, Bruno Royer, Laurent Voillat, Cyrille Hulin, Anne Banos, Eric G. Voog, Anne-Marie Stoppa, Lofti Benboubker, Niels Abildgaard, Katell Le Du, Philippe Moreau, Thierry Facon, Sonja Zweegman, Margaret MACRO, Francesca Gay, Evangelos Terpos, Xavier Leleu
Journal: Blood (2015)
Serologic evidence of Coxsackievirus etiology of congenital heart disease
Authors: G. C. Brown
Journal: JAMA (1967)

The incidence of certain virus infections in pregnant women was determined serologically in an effort to demonstrate their possible association with congenital anomalies. Significantly more mothers of infants with congenital heart disease were shown to have experienced infection with coxsackieviruses than did matched control women. Coxsackievirus B types 3 and 4 were most frequently associated with malformed infants. Most infections were shown to have occurred during the first trimester of pregnancy. Patient diaries of illness kept by women during pregnancy revealed that half of the infections were completely subclinical. No difference in incidence of infection with other viruses between the anomaly and control groups could be demonstrated.
Leads from the MMWR. Rubella outbreaks among office workers--New York City
Journal: JAMA (1983)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
MA 07.01 Patients with ALK IHC-Positive/FISH-Negative NSCLC Benefit from ALK TKI Treatment: Response Data from the Global ALEX Trial
Authors: T. Mok, S. Peters, D.R. Camidge, S. Gadgeel, S. Ignatius Ou, D. Kim, R. Dziadziuszko, F. De Marinis, R. Sangha, A. Zeaiter, J. Noe, E. Nueesch, T. Liu, I. Loftin, C. Williams, A. Shaw
Journal: Journal of Thoracic Oncology (2017)
Errata
Authors: Mr Graham, Mr Hatebett, Appointments Travers, Mr Lawrence, Edward Stanley, Joseph Green, Charles Aldis, Thomas Ingle, M Huguier, George Magrath, Southwood Smitb, Nagent Peter, John Kingston, J Jones, G Winstone, J Leslie, J Dukes, F Greenwood, T Forster, F Farmer, W Giil, James Lancashire, Wv Doravilie, W Vidal, H Shelley, C Markus, W Ackland, W Blvth, J Turner, J Holloway, C Evans, A Walters, J Paterson, J Adolphus, W Buxton, William Cook, Edmond Archer, London Michael, Hoole Ashwell, Stafford- Shire Longdon, July Thursday, Alfred Henry, Bradford Warburton, Jas Braid, Crediton Empson, Oliver Land, Birmingham Pemberton, Robert Hugh, John Price, William Paddington, Esq Lerew, Henry Ronalds
Journal: BMJ (1847)
The Future of Primary Care
Authors: Clifton R. Cleaveland
Journal: Annals of Internal Medicine (2004)

Letters6 January 2004The Future of Primary CareClifton R. Cleaveland, MDClifton R. Cleaveland, MDFrom Chattanooga, TN 37403.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-140-1-200401060-00024 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:The supplement on The Future of Primary Care would have been strengthened by more participation from general internists who practice daily in the trenches. I do not know if we can endure until the laudable recommendations of the writers can be effected. We survive only by being able to see more and more patients in our workday. These patients are amazing in their complexity. I doubt that their care could be relegated to nonphysicians.I recommend the following near-future strategies for helping general internists: 1) All subspecialty societies of medicine should pledge their active support for improved ... Author, Article, and Disclosure InformationAuthors: Clifton R. Cleaveland, MDAffiliations: From Chattanooga, TN 37403. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoThe Future of Primary Care Harold C. Sox The Future of Primary Care Clair Morud The Future of Primary Care Scott A. Shipman , Jon D. Lurie , and David C. Goodman Metrics 6 January 2004Volume 140, Issue 1Page: 69KeywordsForecastingHealth care qualityPrimary care physiciansSub-specialty care ePublished: 6 January 2004 Issue Published: 6 January 2004 Copyright & PermissionsCopyright © 2004 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
TENDER PRESSURE POINTS WITH SO-CALLED SYMPTOMLESS GALLSTONES
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
LIQUID AIR.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Increasing deaths from asthma.
Journal: BMJ (1968)

PointersDeath from Asthma: Investigation into apparent increase in mortality shows this to be a true bill in England and Wales, particularly in adolescent age group.No comparable increase observed in other countries.Possible connexion with drugs used has been studied but results are not conclu- sive (,,p.335 and 339).Leader this page.Complete Heart Block: Transvenous system of permanent artificial pacemaking found safe and reliable, requiring minimal follow-up when patients are instructed in the hazards and treat- ment of instrument failure (p.343).
Cardiomyocyte GATA4 functions as a stress-responsive regulator of angiogenesis in the murine heart
Authors: Joerg Heineke, Mannix Auger-Messier, Jian Xu, Toru Oka, Michelle A. Sargent, Allen York, Raisa Klevitsky, Sachin Vaikunth, Stephen A. Duncan, Bruce J. Aronow, Jeffrey Robbins, Timothy M. Crombleholme, Jeffery D. Molkentin
Journal: Journal of Clinical Investigation (2008)

During the preparation of the manuscript, an error occurred in the wording of the final sentence of the abstract.The correct sentence appears below.To our knowledge, these results demonstrate a previously unrecognized function for GATA4 as a regulator of cardiac angiogenesis through a nonhypoxic, load, and/or disease-responsive mechanism.The JCI regrets the error.
Correlation of Clinical and Hemodynamic Studies in Patients with Mild and Severe Anemia with and Without Congestive Failure
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract LB-204: Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis in Wilms tumors
Authors: Dinesh Rakheja, Kenneth S. Chen, Yangjian Liu, Tsung-Cheng Chang, Abhay A. Shukla, James Malter, Joshua T. Mendell, James F. Amatruda
Journal: Cancer Research (2014)

Abstract Wilms tumor is the most common pediatric kidney cancer and the fourth most common childhood cancer overall. It is treated with a combination of surgery, chemotherapy, and radiation, and, while most children are cured, survival remains poor in those with advanced-stage disease. Known driver mutations (in WT1, WTX, and CTNNB1) account for only one-third of Wilms tumor cases. To better define the genomic landscape of Wilms tumor, we performed whole-exome sequencing of 44 Wilms tumors. We also sequenced matched germline DNA by whole-exome sequencing (15 cases) or targeted Sanger sequencing of candidate mutations (29 cases) to identify somatic mutations. Through this approach, we identified recurrent somatic mutations in MYCN, DROSHA, and DICER1 which were mutually exclusive with known Wilms tumor mutations in WT1 and CTNNB1. The ribonucleases DROSHA and DICER1 perform two key steps in the biogenesis of microRNAs (miRNAs), which are ∼22-nt non-coding RNAs that regulate the stability and translation of target mRNAs. DROSHA and DICER1 mutations occurred at or near conserved metal-binding residues in their ribonuclease (RNase) IIIB domains. In vitro processing assays modeling these mutations showed that they partially or completely disrupt the ribonuclease activity of DROSHA and DICER1. In addition, next-generation sequencing of small RNAs in these tumors revealed that the DICER1 mutations preferentially impaired processing of miRNAs derived from the 5′ arm of pre-miRNA hairpins, including the let-7 tumor suppressor miRNA family. Although DROSHA-mutant tumors did not exhibit skewed expression of 5′ vs. 3′-derived miRNAs, expression of let-7 and other putative tumor suppressor miRNAs was reduced in these tumors as well. While germline and somatic mutations in DICER1 have been reported in some cancers, this is the first report of recurrent DROSHA mutations in any human tumor type. Moreover, these results suggest that impairment of miRNA processing by somatic mutation of DROSHA and DICER1 defines a novel subclass of Wilms tumor. Citation Format: Dinesh Rakheja, Kenneth S. Chen, Yangjian Liu, Tsung-Cheng Chang, Abhay A. Shukla, James Malter, Joshua T. Mendell, James F. Amatruda. Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis in Wilms tumors. [abstract]. In: Proceedings of the 105th Annual Meeting of the American Association for Cancer Research; 2014 Apr 5-9; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2014;74(19 Suppl):Abstract nr LB-204. doi:10.1158/1538-7445.AM2014-LB-204
Caspar Wistar (1761-1818) Philadelphia Anatomist
Journal: JAMA (1969)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Progress and Deficiencies in the Registration of Clinical Trials
Authors: Michio Ozeki
Journal: New England Journal of Medicine (2011)

corrections ly returned to school and has received daily oral propranolol for 10 months (Fig. 1, inset c).The blood VEGF level decreased remarkably after the administration of propranolol.However, it is premature to conclude that the reduction in VEGF defines its role in the mechanism of action.The prognosis for patients with diffuse lymphangiomatosis is poor if the condition is resistant to standard therapies.
PROGNOSTIC IMPLICATIONS OF NON-OBSTRUCTIVE CORONARY PLAQUES IN PATIENTS WITH NON-ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION - A MULTIDETECTOR COMPUTED TOMOGRAPHY STUDY
Authors: Klaus F. Kofoed, Thomas S. Kristensen, Tobias Kühl, Walther B. Nielsen, Michael B. Nielsen, Henning Kelbæk
Journal: Journal of the American College of Cardiology (2010)
Treatment of trigeminal neuralgia
Authors: H. A. Shenkin
Journal: JAMA (1982)

<h3>In Reply.—</h3> My editorial did not, in any way, imply criticism of an older generation of neurosurgeons. Indeed, as with all medical advances, we build on the experience and good efforts of those who have gone before us. I believe that Dr Shenkin has evolved an unusual interpretation of my remarks.
The Cover
Authors: Carol E. Hevner
Journal: JAMA (1987)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
<i>The Dock Family</i>. A Study in Hereditary Lack of Emotional Control. By Mrs. Anna Wendt Finlayson, Field Worker of Warren State Hospital, Warren, Pa. With Preface by Charles B. Davenport. (<i>Cold Spring Harbor, Long Island, N. Y.: Eugenics Record Office, 1916</i>.)
Authors: W. R. D.
Journal: American Journal of Psychiatry (1916)
Specialty Board certification as a measure of professional competence
Authors: W. D. Holden
Journal: JAMA (1970)

Today there are basically three methods of recognizing, formally and publicly, professional competence to provide medical services to the public. These consist of receipt of the MD degree, acquisition of a license to practice medicine, and certification by a specialty board. The historical development of these methods of recognition is a fascinating and almost incredible story, documented most effectively by Shryock.<sup>1</sup>The history of this development displays degrees of parochialism by medical educators, practitioners, and administrators alike that could easily deter the most sanguine advocate for change from proceeding with any realistic analysis of existing conditions and recommendations for improvement. If the medical profession intends to keep its own house in order, however, it must recognize the changing significance of the MD degree, state licensure, and board certification. Adaptation to the changes is essential if these awards are to be meaningful to the individual, the profession, and the public.
MILITARY PROJECTILES.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal