tbuckley/cabot-search huggingface dataset:
The Use of K X-Ray Fluorescence for Measuring Lead Burden in Epidemiological Studies: High and Low Lead Burdens and Measurement Uncertainty
Authors: Howard Hu, Fred L. Milder, Doug E. Burger
Journal: Environmental Health Perspectives (1991)

X-ra fluorce (XRJ, a napid, noninasve, low nmethod ofm ing bone lead content, has emerged as a promising tool for providing an integrated estimate of low4evel lead accumulation in epidemiokogial studies.Our group has settled on an XRF mtthat utilizes K X-rays (K-XRF) and malizes the measurement to bone calcium.The unit of measurement provided is in micrograms of lead/gram bone mineral, an accurate proxy for micrograms of lead/gram bone ash.An estimate of _ uncertainty is g ed from thecounting statistics and is teretically dependent on several factors, primarily duration ofmeasurement and bone mass.Data from pilot studies ofcommunity- oxoed adults and workers with varying degrees ofoccupational lead exposure demonstrated that the K-XRF instrmnt can easily is sh between populations with occupational versus environmental lead exposures.Among all subjects, bone lead increased with age.Larger measurement uncertainty was significantly associated with being female, greater subject weight, and smaller lead burdens.
Treatment of Intention Tremor
Journal: JAMA (1994)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Council on Drugs. List No. 102. New names
Journal: JAMA (1971)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Fatal occupational injuries
Authors: S. P. Baker
Journal: JAMA (1982)

Deaths resulting from work-related injuries during a one-year period in Maryland were identified and reviewed. Of 148 workers killed, all but two were male. Transportation vehicles were involved in 41% of the deaths, with road vehicles accounting for 25% of the total. Other major groups involved nonroad land vehicles (16%) and firearms, primarily handguns (11%). Two thirds of the workers died at the scene or were dead on arrival at the hospital. Head injuries were the most common cause of death. Eleven percent of the workers tested had blood alcohol concentrations of 0.08% by weight or greater. The majority of the deaths involved either hazards that are not addressed by the Occupational Safety and Health Act of 1970 or workers in categories that are excluded by law from regulation under this act. (<i>JAMA</i>1982;248:692-697)
Quantitative Urinalysis
Authors: Daniel M. Musher
Journal: JAMA (1976)

Using a hemocytometer, we determined the number of white blood cells (WBCs) per milliliter in uncentrifuged urine specimens. Uninfected urine usually contained ≤ 10<sup>3</sup>WBCs per milliliter, although up to 8×10<sup>3</sup>WBCs per milliliter were observed. Infected urine regularly contained &gt;10<sup>4</sup>WBCs per milliliter, and the mean WBC count per millimeter for urine from infected patients was 3.1×10<sup>5</sup>. The absence of pyuria thus provides strong evidence against the presence of urinary tract infection. Similar results were obtained in patients who had indwelling catheters, suggesting that bacteriuria reflects the presence of infection rather than colonization. Valid data are easily obtainable by quantitative urinalysis of uncentrifuged urine specimens. There are obvious differences in WBCs per milliliter, with little overlap between infected and uninfected urine. This method of analysis should replace traditional means of counting WBCs per visual field in a centrifuged, resuspended urine sediment. (<i>JAMA</i>236:2069-2072, 1976)
Oncology
Authors: E. J. Freireich
Journal: JAMA (1978)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Sexual Dimorphism of Brain Aromatase Activity in Medaka: Induction of a Female Phenotype by Estradiol
Authors: Ana Clara Melo, John S. Ramsdell
Journal: Environmental Health Perspectives (2001)

In this study we identified sex-dependent dimorphism of brain aromatase in the teleost medaka and examined its regulation by sex steriods. We first investigated differential distribution of brain aromatase activity in sexually mature male and female medaka in serial coronal sections of the brain and identified the hypothalamic nuclei contained in each section using the brain atlas of medaka. In the brain of male medaka, high levels of activity are localized in sections containing the preoptic (POA) and suprachiasmatic nuclei (SC) (63-75 fmol/hr) and low levels in the nuclei periventricular dorsalis (HD), ventralis (HV), and caudalis (Hc), nuclei diffusus of lobulus inferiores (NDIL), and nuclei tuberi anteriores (TA) and posteriores (TP) (< 25 fmol/hr). In the brain of female medaka high aromatase activity is localized in sections containing the HD, HV, Hc, NDIL, TA, and TP (85-80 fmol/hr) and highly variable levels in the POA and SC (23-70 fmol/hr). The concentration and time dependency of the exposure of male medaka to estradiol on the total brain aromatase activity and morphologic sex characteristics were determined next. Estradiol increased the activity of brain aromatase in a concentration-dependent manner at 2.5 and 25 microg/L, but the increase was lower at higher concentrations of the hormone. The effect was time dependent, gradually increasing up to the fifth day of exposure, after which it reached a plateau. Estradiol induction of brain aromatase analyzed using Lineweaver-Burke plots of saturation assays revealed a non-first-order reaction. The results indicate that a positive feedback mechanism regulates brain aromatase and imply that the sexual dimorphic distribution of aromatase may be highly sensitive to physiologic cues and environmental perturbations in fish.
British Journal of Urology, London
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Special Studies
Journal: JAMA (1967)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 12898: Cigarette Smoking is Associated With Rapid Renal Function Decline in African Americans in The Jackson Heart Study
Authors: Michael E Hall, Wei Wang, Alan Penman, Victoria Okhomina, Albert W Dreisbach, Luis A Juncos, John E Hall, Michael D Winniford, Bessie A Young
Journal: Circulation (2015)

Background: Controversy exists regarding the association of cigarette smoking and renal dysfunction, particularly among African Americans who are disproportionately affected by chronic kidney disease (CKD). Therefore, we evaluated the relationship between cigarette smoking and rapid renal function (RRF) decline in the Jackson Heart Study (JHS). Methods: We evaluated the rates of RRF decline among a cohort of 5,301 African Americans enrolled as part of the JHS. Of those, 3648 with baseline creatinine were included for study. Estimated glomerular filtration rate (eGFR) was calculated using the CKD-EPI equation. RRF decline was defined as an absolute decline of 30% over 10 years. Smoking status was defined as current, past (smoked at least 400 cigarettes/life) or never smoker. Poisson regression models were performed to estimate the association of smoking status with RRF decline. Results: There were 422 current, 659 past and 2567 never smokers identified at Visit 1. After adjustment for age, gender, BMI, diabetes, hypertension and total cholesterol, current smokers demonstrated a significantly higher incidence of RRF decline compared with never smokers (IRR 1.86, 95% CI 1.35-2.56). Current smokers using 1-19 cigarettes daily and ≥20 cigarettes daily also had an increased incidence of RRF decline (IRR 1.73, 95% CI 1.18-2.54 and IRR 2.03, 95% CI 1.23-3.35, respectively). There was a significant, stepwise reduction in eGFR from Visit 1 to Visit 3 in current and past smokers compared to never smokers (Figure). Conclusions: In a large cohort of African Americans, current cigarette smoking was independently associated with RRF decline in a dose-dependent manner.
Rio Back Home
Journal: Environmental Health Perspectives (1993)

a ~~lp Iĩ n order and stop defining success only in terms of quarterly earnings, we can play a major leadership role."Summarizing the conference, Hutton concluded, "Business doesn't just reflect the values of society, busi- ness helps shape those values.Advertising and marketing should proclaim that the environment is a value that the business community cherishes as much as the bottom line."
New Laser Target: Otitis Media
Authors: M. Mitka
Journal: JAMA (1999)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Evaluation of the WHO clinical case definition for AIDS in Uganda
Authors: R. Widy-Wirski
Journal: JAMA (1988)

Infections with human immunodeficiency virus are common in areas of the world where laboratory testing and sophisticated diagnostic facilities are unavailable. A World Health Organization clinical case definition for acquired immunodeficiency syndrome was developed in 1985 for use in such areas. In 1987, we tested this definition on 1328 inpatients and outpatients in 15 hospitals throughout Uganda. Five hundred sixty-two patients (42%) were positive by enzyme-linked immunosorbent assay for human immunodeficiency virus antibody. The World Health Organization definition had a sensitivity of 55%, a specificity of 85%, and a positive predictive value of 73%. Modification of the case definition by excluding a known cough from tuberculosis as a minor criteria decreased sensitivity slightly to 52%, but specificity and positive predictive value increased to 92% and 83%, respectively. Amenorrhea, although not specifically asked about, was a symptom noted by many female patients (26% of females who were positive by enzyme-linked immunosorbent assay); as a symptom indicative of human immunodeficiency virus infection, amenorrhea had a specificity of 99%, with a positive predictive value of 89%. These findings support the generalizability of the World Health Organization clinical acquired immunodeficiency syndrome definition and its use (especially the modified version) in areas of Uganda without sophisticated facilities. (<i>JAMA</i>1988;260:3286-3289)
SCIENTIFIC PROGRAM ABSTRACTS
Authors: None &NA;
Journal: Clinical Nuclear Medicine (1981)

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Heavy Metal Contamination from Geothermal Sources
Authors: J. Eleonora Sabadell, Robert C. Axtmann
Journal: Environmental Health Perspectives (1975)

Liquid-dominated hydrothermal reservoirs, which contain saline fluids at high temperatures and pressures, have a significant potential for contamination of the environment by heavy metals. The design of the power conversion cycle in a liquid-dominated geothermal plant is a key factor in determining the impact of the installation. Reinjection of the fluid into the reservoir minimizes heavy metal effluents but is routinely practiced at few installations. Binary power cycles with reinjection would provide even cleaner systems but are not yet ready for commercial application. Vapor-dominated systems, which contain superheated steam, have less potential for contamination but are relatively uncommon. Field data on heavy metal effluents from geothermal plants are sparse and confounded by contributions from
What's new this month in BMJ Journals
Authors: Harvey Marcovitch
Journal: BMJ (2004)

A two year follow up of 92 New Zealand patients who underwent phacoemulsification for cataract has shown that 95% maintained “best spectacle corrected visual acuity” of 6/12 or better. This was despite 18 developing new systemic illness, as might be expected in this elderly cohort, and 10 experiencing new ocular disease such as glaucoma or the need for lid surgery. Overall, three quarters of patients were satisfied with their vision. As the long term result of cataract surgery is poorly documented, the investigators intend to keep these patients under review. Br J Ophthalmol 2004;88: 1042–8 [OpenUrl][1][Abstract/FREE Full Text][2] Investigators in Scotland were prompted by reading the diaries of the late Alan Clark to rethink the early symptomatology of brain tumours. (Clark described gradually increasing fatigue, problems with concentrating, and feelings of anxiety as well as intermittent headache.) They visited at home 92 … [1]: {openurl}?query=rft.jtitle%253DBritish%2BJournal%2Bof%2BOphthalmology%26rft.stitle%253DBr%2BJ%2BOphthalmol%26rft.issn%253D0007-1161%26rft.aulast%253DThompson%26rft.auinit1%253DA%2BM%26rft.volume%253D88%26rft.issue%253D8%26rft.spage%253D1042%26rft.epage%253D1048%26rft.atitle%253DThe%2BAuckland%2BCataract%2BStudy%253A%2B2%2Byear%2Bpostoperative%2Bassessment%2Bof%2Baspects%2Bof%2Bclinical%252C%2Bvisual%252C%2Bcorneal%2Btopographic%2Band%2Bsatisfaction%2Boutcomes%26rft_id%253Dinfo%253Apmid%252F15258022%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/ijlink?linkType=ABST&journalCode=bjophthalmol&resid=88/8/1042&atom=%2Fbmj%2F329%2F7467%2F646.atom
A Simple Technique for Fat Biopsy of PBB-Exposed Individuals
Authors: Susan M. Daum, Jerome Knittle, Kenneth Rosenman, William N. Rom, Edwin C. Holstein
Journal: Environmental Health Perspectives (1978)

A simple nonsurgical technique of obtaining fat samples by aspiration from the gluteal prominence was developed by Hirsh in 1960 and has been in use in our Nutrition Clinic at the Mount Sinai Hospital for several years. We have modified it for field use and the analysis of fat-soluble hydrocarbon residues. All the materials which will contain the fat sample to be analyzed are washed with acetone and pesticide residue-free hexane, and a 15 gauge needle and 33 cc syringe are sterilized. Aspiration of fat from the lateral gluteal prominence is accomplished under local xylocaine anesthetic. The anesthetic also serves as the vehicle into which the fat is broken by the shearing action of the 15 gauge needle. Fat particles are sucked into the syringe by a constant vacuum kept on the syringe during lateral movement of the needle under (and parallel to) the skin within the gluteal fat pad; 200--500 ml of fat can be obtained for hydrocarbon residue analysis. The only complications have been some mild hematomas at the site of the aspiration. The method avoids surgical biopsy and sutures and takes about 7--8 min.
Manuscripts Approved for JNCI, November 1 to December 1, 1968
Journal: JNCI Journal of the National Cancer Institute (1969)

Journal Article Manuscripts Approved for JNCI, November 1 to December 1, 1968 Get access JNCI: Journal of the National Cancer Institute, Volume 42, Issue 1, January 1969, Pages 204–205, https://doi.org/10.1093/jnci/42.1.204-a Published: 01 January 1969
Resolution of paraneoplastic bile duct paucity following successful treatment of Hodgkin's disease
Authors: O Crosbie
Journal: Hepatology (1997)

We report the case of a 21-year-old woman who developed severe adult onset ductopenia in association with Hodgkin's lymphoma. Chemotherapy resulted in a remission of her Hodgkin's disease (HD) and significant improvement in liver function with resolution of the hepatic and biliary duct histological abnormalities, a therapeutic success not previously described in the literature.