tbuckley/cabot-search huggingface dataset:
Platelet Transfusion Therapy
Authors: Peter A. Daly
Journal: JAMA (1980)

Seventy-nine platelet transfusions to 73 thrombocytopenic patients with cancer were analyzed to determine whether a platelet count obtained one hour after transfusion could help differentiate between alloimmunization and other clinical factors that result in rapid platelet destruction. These transfusions were selected because 18- to 24-hour increments were inadequate in response to fresh, random donor platelets. A corrected count increment (CI) (CI=[posttransfusion count—pretransfusion count]×body surface area [sq m]/platelets transfused×10<sup>11</sup>) at one hour of 10×10<sup>3</sup>/μL or greater was associated with absence of lymphocytotoxic antibody, whereas increments of less than 10×10<sup>3</sup>/μL were generally associated with high levels of strongly cytotoxic antibody. HLA-matched transfusions produced no improvement in increments when the previous one-hour CI had been 10×10<sup>3</sup>/μL or greater, whereas in the other group significantly better increments were obtained. A one-hour posttransfusion count is a simple test that correlates well with the presence of antibody against HLA antigens, is valuable in predicting the need for HLA-matched platelets, and helps avoid wasteful, empirical use of such transfusions. (<i>JAMA</i>243:435-438, 1980)
Evaluation of a new reactive solid phase for radioimmunoassay of serum specific IgE against muscle relaxant drugs
Authors: J. L. Gueant, E. Mata, B. Monin, D. A. Moneret‐Vautrin, L. Kamel, J. P. Nicolas, M. C. Laxenaire
Journal: Allergy (1991)

Until now, immunoassays for detection of anti‐muscle relaxant IgE in serum have been performed with the drug coupled to epoxy‐activated Sepharose or to RAST papers dics. In the present work we have used a quaternary ammonium‐Sepharose in which the quaternary ammonium reactive group (choline chloride) was directly coupled to Sepharose via an ether linkage. 50 μl of the quaternary ammonium solid phase (QAS) was incubated with 50 μl of serum for 3 h, washed, incubated 18 h with 125 I‐anti‐IgE and washed again. The results were expressed as the percentage of 125 I‐anti‐IgE adsorbed onto the solid phase. The results were at 1.30.5% for 20 control sera, with an upper normal limit estimated to 2.3%. The within‐run reproducibility ranged from 3.2% to 10.0%. The results were significantly correlated with those obtained with either alcuroniumepoxy‐Sepharose, choline‐epoxy‐Sepharose, the RAST‐alcuronium or with the RAST‐succinyl choline (respectively, r = 0.66, r = 0.80, r = 0.81, r = 0.40 and r = 0.85). The values obtained with the sera of 83 patients ranged from 0.3 to 38.5%. The sensitivity was estimated at 87.9%, 66.7% and 40.7% with the QAS‐RIA, the RAST‐succinyl choline and the RAST‐alcuronium, respectively. The inhibition of adsorption of specific IgE onto the gel ranged from 13.0 to 90.6% in presence of 130 nmol of soluble muscle relaxants. In 83.3% of 30 cases, the highest inhibition was obtained with the muscle relaxant which was clinically incriminated. In conclusion, the reactive‐solid phase which was used in the present work significantly increased the sensitivity of detection of anti‐muscle relaxant IgE in serum.
Anniversary meeting of the British Medical Association
Journal: BMJ (1841)

took the chair at seven o'clock P. m.The CHAIRMAN, in opening the business, said, that they were assembled on the very apot where, four years ago, this assoiation received its final impress.At that time it was predicted that it would not be of long continuance; but those predictions had proved untrue.None of the cororators then attended the meeting, though they were aLware of its being held, to oppose any of the propositions ahid before it.One gentleman, who attended from a liberal insttution, was so fnrihtened with the picture which it was \ne eAsaryto dra of the corporations, that he left the room, ad had never since returned.(Laughter.)They had now arrived at an important crisis.Having aroused the pro- fession from the apathy into which it had sunk, its present ea and energy must be tumed to some good account.theirs was the cause of reason, ofjustice, and of the public a therefore it required none of the aids of rhetoric i advrocate it.Many of the objects which the association Iad in view at its foundation had been fully realized.A dege of unity now existed in the profession which never prevailed before.The benevolent fund had been favourably progiessing.(Cheers.)One obect to be steadily kept in view, ras the enlightenment of the public mind.the battle about to be fought was emphatcall that of the public.
Neuroblastoma
Authors: Ruth Andrea Seeler
Journal: JAMA (1976)

This lucidly written monograph superbly organizes the vast literature dealing with this fascinating pediatric tumor. Authoritative chapters delineate the multifaceted clinical problems including congenital neuroblastoma, head and central nervous system involvement, abdominal and chest problems, and metastatic skeletal complications. The unique biological properties are covered in specific chapters dealing with catecholamine metabolism, histology, immunology, and the potential for immunotherapy. The therapeutic modalities, surgery, radiotherapy, and chemotherapy are discussed in detail and as they interrelate with each other. Eight of the 13 chapters have been written by Dr Pochedly, and the others are well written and edited to ensure uniformity of literary quality. All are profusely illustrated with charts, high quality x-rays, and graphs that present this complex subject with extreme clarity—especially important for those not intimately familiar with this tumor and its multiple clinical vagaries. The bibliographies are extensive and rather inclusive. At present, the ultimate answer to curing neuroblastoma
Strictum et Laxum
Journal: JAMA (1970)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
RETENTION OF LIFE.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
<i>A Manual of Autopsies, Intended for the Use of Hospitals for the Insane and other Public Institutions.</i>By I. W Blackburn, M. D., Pathologist to the Government Hospital for the Insane, Washington, D. C. Illustrated. Philadelphia, P. Blakiston, Son &amp; Co. 1892. (12 mo., pp. viii-84.)
Journal: American Journal of Psychiatry (1892)
Nosocomial Enterococci Resistant to Vancomycin—United States, 1989-1993
Journal: JAMA (1993)

As part of continual surveillance for antibiotic resistance among pathogens associated with nosocomial infections, a recent analysis of data reported to CDC's National Nosocomial Infections Surveillance (NNIS) system demonstrated a 20-fold increase in the percentage of enterococci associated with nosocomial infections that are resistant to vancomycin from January 1, 1989, through March 31, 1993. Many of these strains are resistant to all available antimicrobial agents. This report summarizes that analysis.
Erratum
Journal: JNCI Journal of the National Cancer Institute (1993)

“Psychological Distress and Breast Cancer Screening Among Women at High Risk: Where Are We?“—correspondence from Michael E. Stefanek [J Natl Cancer Inst 84:1756–1757 (Issue 22)].We inadvertently omitted several lines of text from this letter. The first paragraph should read, in part, “Major findings by Kash et al. ( 1 ) included significant psychological distress among women at high risk, including an “immobilizing” anxiety that prevents women from taking preventive actions. Vogel and Bondy ( 2 ) noted, and Kash ( 3 ) concurred, that the sample of women may have biased the findings; i.e., women at high risk attending special clinics may be different from women at high risk not attending such clinics. In a recent investigation ( 4 ) assessing compliance with screening in a sample of women at high risk not attending special clinics, we found poor BSE compliance, while clinical breast examination adherence was quite high (84%), although mammography adherence in the preceding year (54%) was poor.” The Journal regrets the error.
Antibodies against the Acetylcholine Receptor in Hematologic Disorders: Implications for the Development of Myasthenia Gravis after Bone Marrow Grafting
Journal: New England Journal of Medicine (1987)

Correspondence from The New England Journal of Medicine — Antibodies against the Acetylcholine Receptor in Hematologic Disorders: Implications for the Development of Myasthenia Gravis after Bone Marrow Grafting
The future of family practice. Implications of the changing environment of medicine. Council on Long Range Planning and Development in cooperation with the American Academy of Family Physicians
Journal: JAMA (1988)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Poetry and Medicine
Authors: Jon Mukand
Journal: JAMA (1989)

"Cells" by Phyllis Janowitz originally appeared in Visiting Rites (Princeton, NJ: Princeton University Press; 1984) and is reprinted by permission of the poet. The poem is included in Mukand J, ed: Sutured Words: Contemporary Poetry About Medicine (Brookline, Mass: Aviva Press [PO Box 1357]; 1987).
Clinical Pediatric Oncology
Authors: Ruth Andrea Seeler
Journal: JAMA (1973)

<i>Clinical Pediatric Oncology</i>, edited by Sutow, Vietti, and Fernbach, and coauthored by members of the Pediatric Division of the Southwest Cancer Chemotherapy Study Group, fills a long-present void. This comprehensive, authoritative, readable text is well written in good literary style, with excellent illustrations, tables, and graphs. The individual chapters present a complete discussion of particular areas. The necessary duplications that are present are an advantage, since much of the text will be used in segments and it's nice not to have to keep flipping to other areas of the book. The initial quarter of the text deals with the fundamental principles of pediatric oncology. Unfortunately, many casual readers who might use only specific disease sections will miss one of the best writings on the subject. The chapters on etiology, principles of radiotherapy, total care, cellular kinetics, and chemotherapy should be mandatory reading for every physician caring for children with malignant
PURE MILK IN INFANT FEEDING.
Journal: JAMA (1904)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
TO EVALUATE THE SAFETY AND OUTCOMES OF ESD AND HYBRID ESD FOR LARGE SESSILE COLORECTAL POLYPS INCLUDING PROCEDURAL COMPLICATIONS AND RECURRENCE RATE
Authors: S M Ali, N Radhakrishnan, R Hammonds, R George
Journal: Gut (2013)

<h3>Introduction</h3> The purpose of ESD and Hybrid ESD (circumferential excision and snaring) is to obtain en bloc specimen. Margins are checked for residual tissue and APC applied if appropriate. <h3>Method</h3> Single endoscopist using ESD and Hybrid ESD (H-ESD) technique was retrospectively audited from April 2004 to August 2012. Service evaluation data of 38 patients with large sessile polyps who underwent ESD and Hybrid ESD was reviewed from a cohort of 224 colonoscopies referred for large polyp EMR. All procedures were intended as ESD. NICE recommendations for case selection were followed in 92% cases. Due to challenges in submucosal dissection of the large lesions, piecemeal resection was done after circumferential cutting. First follow-up endoscopy was performed at 3-6 months and the second at 12–14 months. <h3>Results</h3> Mean age was 70 with 16 males and 22 females. Mean size of polyp in ESD group was 26 mm. Range 15–50 mm. Mean size in the H-ESD group was 49 mm. Range 20–100 mm. Complete resections were achieved in 17 (44%) out of 38 cases. Due to piecemeal resection pathologists were not able to confirm adequacy of excision in 12 cases. In 9 cases resection was reported incomplete on index procedure. ESD performed in 13 (34%) cases. Complete resection achieved in 6. Out of 7 incomplete resections in the ESD group, 3 were reported by pathologists as lesion extending to the lateral margin hence incomplete excision. Histology did not comment on margin clearance in 3 ESD. 1 ESD was a sub mucosal lipoma on histology. This was an unintentional ESD for lipoma. Histology: ESD group: TVA with LGD 7, TVA with HGD 5. H-ESD was performed in 25 (65.7%) cases. Complete resection achieved in 11 cases, incomplete resection in 7 and lateral margin clearance not confirmed in 7 H-ESD cases due to piecemeal resection. Histology: H-ESD group: TVA with LGD 16, TVA with HGD 6 and adenocarcinoma in 2 cases-one9s lateral and deep margins were clear and the other was incomplete and referred to MDT. In 4 ESD and 7 H-ESD cases there was minor bleeding controlled endoscopically at the time. 1 delayed post- HESD bleeding required 11 days of hospital stay and 2 units of blood transfusion. 1 retroperitoneal perforation and 1 case of serosal cut managed conservatively with clips and antibiotics. APC performed in 16 (42%) out of 38. Recurrence was identified in 6 H-ESD cases (15.7%). 5 local recurrences detected at 3 months and 1 local recurrence detected at 24 months.In 13 ESD cases no perforation or recurrence upto 14 months was noted despite 5 histologically incomplete dissections. <h3>Conclusion</h3> ESD in bowel is challenging and has a long learning curve. These procedures should be performed by trained endoscopists in accredited units and a national registry should be maintained.
State-Specific Trends Among Women Who Did Not Receive Prenatal Care—United States, 1980-1992
Journal: JAMA (1995)

Lack of prenatal care is strongly associated with an increased risk for low birthweight (< 2500 g [< 5 lbs 8 oz] at birth) infants, preterm delivery, and maternal and infant mortality (1). From 1980 through 1992, the nationally aggregated percentage of pregnant women who did not receive prenatal care increased by 31%--from 1.3% to 1.7% (2,3). Because nationally aggregated data can obscure variations among states, CDC analyzed state-specific data derived from birth certificates for 1980-1992 to examine trends among women who did not receive prenatal care. This report summarizes the findings of the analysis.
THE ANTIVIVISECTIONISTS AGAIN.
Journal: JAMA (1897)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
"ALCOHOL, ARSPHENAMIN AND THE WASSERMANN TEST"
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
OA 04.03 Primary Tumor Resection versus Maintenance Therapy for Patients with Oligometastatic Non-Small Cell Lung Cancer
Authors: X. Kang, H. Zhou, W. Yan, L. Dai, Y. Yang, H. Yang, H. Fu, M. Fan, Y. Lin, Z. Liang, H. Xiong, K. Chen
Journal: Journal of Thoracic Oncology (2017)
CREMATION AND THE CATHOLIC CHURCH
Journal: BMJ (1910)

on "Hay Fever," almost answers itself.The com- plaint, that I did not give credit to the gentleman who first used morphia combined with atropia, is not pertinent, inasmuch as the purpose of the paper was not to give a history of the various drugs recom- mended, but to give the Hay Fever Association the results of my study of the disease."Subscriber" does not say that Dr. Morehead, of England, pre- ceded me in the use of morphia and atropia, com- bined, as I recommended, for hay fever.I do not know that he did.I believed that I was the first to discover the efficacy of this prescription in hay fever, although I did not so state in the paper.I have used this prescription for several years successfully, not knowing that any one else had employed it ex- cept through my advice.Evidently the new mem- bers of the United States Hay Fever Association had not heard of Dr. Morehead's use of this pre¬ scription, for it is not mentioned in the Association's long list of remedies.However, if the remedy is efficacious it matters little who first happened upon the discovery; but if it be worthless, as "Subscriber" avers, I cannot understand why he (or she) is so concerned to have due credit given to the discoverer.The fact that any given remedy may prove a fail¬ ure in the hands of any one medical man, ought not to deter others from giving it a fair trial.I am always thankful for honest criticism from competent critics.
Highlights
Journal: JAMA Surgery (2016)

Diverticulitis Episodes Before Resection and Earlier Interventions 604In this nationwide retrospective cohort study evaluating inpatient, outpatient, and antibiotic prescription claims of 87 461 patients, Simianu et al found that 56.3% of elective resections for uncomplicated diverticulitis occurred after fewer than 3 episodes of diverticulitis.Earlier surgery was not explained by younger patient age, laparoscopy, time between the last 2 episodes preceding surgery, or fi nancial risk-bearing for patients.