tbuckley/cabot-search huggingface dataset:
The Slippery Slope of Legalization of Physician-Assisted Suicide
Authors: William G. Kussmaul
Journal: Annals of Internal Medicine (2018)

Letters1 May 2018The Slippery Slope of Legalization of Physician-Assisted SuicideWilliam G. Kussmaul III, MDWilliam G. Kussmaul III, MDMedia, Pennsylvania (W.G.K.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/L18-0020 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:Dr. Weiser dismisses my approach on the basis that I am a Catholic. He seems to believe that Catholics should not impose our beliefs (for example, that physician-assisted suicide is immoral) on secular society as a whole. Does he believe that I should keep this in mind when contemplating my church's stance on capital punishment, concern for the poor, and other issues? Dr. Weiser might consider that the Catholic Church teaches certain things because they are true. Let's engage on the issues.Dr. Schiller restates my case better than I did in my editorial, and I encourage Annals ... Author, Article, and Disclosure InformationAffiliations: Media, Pennsylvania (W.G.K.)Disclosures: The author has disclosed no conflicts of interest. Form can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M17-2072. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoThe Slippery Slope of Legalization of Physician-Assisted Suicide William G. Kussmaul III The Slippery Slope of Legalization of Physician-Assisted Suicide John K. Weiser The Slippery Slope of Legalization of Physician-Assisted Suicide Gary Schiller Metrics 1 May 2018Volume 168, Issue 9Page: 683-684KeywordsConflicts of interestDisclosureSuicide ePublished: 1 May 2018 Issue Published: 1 May 2018 Copyright & PermissionsCopyright © 2018 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
MRI Scan
Authors: H. David Watts
Journal: JAMA (1994)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Methanol Poisoning
Authors: Hugh H. Hussey
Journal: JAMA (1974)

Methanol (methyl alcohol, wood alcohol) is widely used in a number of industrial processes. Unfortunately, it is also used occasionally—sometimes unwittingly and sometimes knowingly—as a substitute for ethanol (ethyl alcohol) with often drastic or deadly poisonous effects. When such is the case, poisonings tend to occur in clusters. A small group, hard up for a drink of licit liquor, may squeeze the juice out of cakes of Sterno and have a "party." Rarely, as in the incident reported by Bennett et al,<sup>1</sup>methanol poisoning becomes an epidemic. The authors describe the effects of a bootlegger's delivery of 90 gallons of whiskey containing 35% to 40% methanol to the populace of Atlanta during a five-day period in 1951. Of 323 patients observed, 308 were blacks, 15 were whites, 210 were males, and 113 were females, with an age distribution of 10 to 78 years. Forty-one deaths resulted, 22 of them
Extended-Duration Venous Thromboembolism Prophylaxis for Medical Patients
Authors: Michael P. Carson, Yen-Hong Kuo
Journal: Annals of Internal Medicine (2010)

Letters16 November 2010Extended-Duration Venous Thromboembolism Prophylaxis for Medical PatientsMichael P. Carson, MD and Yen-Hong Kuo, PhDMichael P. Carson, MDFrom Jersey Shore University Medical Center, Neptune, NJ 07753.Search for more papers by this author and Yen-Hong Kuo, PhDFrom Jersey Shore University Medical Center, Neptune, NJ 07753.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-153-10-201011160-00020 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:In the EXCLAIM study, Hull and colleagues (1) report the results of their large trial evaluating extended VTE prophylaxis for hospitalized medical patients. It was nice to see transparent reporting of the limitations stated in the abstract and the balanced presentation in the discussion section. We reviewed the article at our resident-run journal club and would appreciate feedback from the authors regarding the reason for reporting nonadjudicated data in Tables 2 and 3 and why they seemed to downplay the risk for major bleeding episodes by stating that the rate was “similar to those seen in previous ...Reference1. Hull RD, Schellong SM, Tapson VF, Monreal M, Samama MM, Nicol P, et al; EXCLAIM (Extended Prophylaxis for Venous ThromboEmbolism in Acutely Ill Medical Patients With Prolonged Immobilization) study. Extended-duration venous thromboembolism prophylaxis in acutely ill medical patients with recently reduced mobility: a randomized trial. Ann Intern Med. 2010;153:8-18. [PMID: 20621900] LinkGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Jersey Shore University Medical Center, Neptune, NJ 07753.Disclosures: None disclosed. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoExtended-Duration Venous Thromboembolism Prophylaxis in Acutely Ill Medical Patients With Recently Reduced Mobility Russell D. Hull , Sebastian M. Schellong , Victor F. Tapson , Manuel Monreal , Meyer-Michel Samama , Philippe Nicol , Eric Vicaut , Alexander G.G. Turpie , Roger D. Yusen , and Extended-Duration Venous Thromboembolism Prophylaxis for Medical Patients Russell D. Hull and Extended-Duration Venous Thromboembolism Prophylaxis for Medical Patients Francesco Dentali , Monica Gianni , and Alessandro Squizzato Extended-Duration Venous Thromboembolism Prophylaxis for Medical Patients Jose A. Nieto , Reina Valle , and Juan B. Lopez-Saez Metrics 16 November 2010Volume 153, Issue 10Page: 689KeywordsAbsolute risk reductionConflicts of interestHemorrhageNumber needed to treatProphylaxisResearch designSafetyVenous thromboembolism ePublished: 16 November 2010 Issue Published: 16 November 2010 Copyright & PermissionsCopyright © 2010 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Road accidents--seat belts and the safe car.
Journal: BMJ (1978)

to take up time-no credit will accrue from this.Not infrequently the examiner hands across the table a specimen, photograph, or data for comment.It is a good principle to describe the exhibit and then, if possible, what it represents.At the end of the interview always leave graciously, however disagreeable it may have been, as this leaves a good impression and in borderline circumstances may be influential.A last word about distinction vivas.These are a battle of wits and knowledge between an above-average examinee and the examiner.The questions are certain to stretch the candidate's knowledge to the utmost but for that reason may be quite enjoyable for both.The process of determining the extent of your knowledge may be long or short, so the length of time taken on the procedure is of little importance.
European Antibiotic Awareness Day provides platform for campaigns on prudent use of antibiotics for the fourth time
Authors: Collective Eurosurveillance editorial team
Journal: Eurosurveillance (2011)

Preview this article: European Antibiotic Awareness Day provides platform for campaigns on prudent use of antibiotics for the fourth time, Page 1 of 1 < Previous page | Next page > /docserver/preview/fulltext/eurosurveillance/16/46/art20018-en-1.gif
RESPONSE: Re: Prostate Carcinogenesis in N-methyl-N-nitrosourea (NMU)-Testosterone-Treated Rats Fed Tomato Powder, Lycopene, or Energy-Restricted Diets
Authors: S. K. Clinton, T. M.-W. Boileau, J. W. Erdman
Journal: JNCI Journal of the National Cancer Institute (2004)
Book: Middlesex
Authors: J. Quin
Journal: BMJ (2002)

Jeffrey Eugenides Bloomsbury, £16.99, pp 529 ISBN0747560234 Rating: ![Graphic][1]</img>![Graphic][2]</img>![Graphic][3]</img>![Graphic][4]</img> Cal Stephanides is a 41 year old Greek-American cultural attaché working in Berlin. In this brilliant novel he looks back on his life as man and … girl. Born Calliope, he has 5α-reductase deficiency. This autosomal recessive disorder is characterised by impaired conversion of testosterone to dihydrotestosterone in androgen-dependent target cells. Thus the inspired Jeffrey Eugenides acknowledges his debt to Imperato-McGinley et al's paper in the Journal of Clinical Endocrinology and Metabolism (1992;75:1022-6). Most patients are raised as females from birth but … [1]: /embed/inline-graphic-1.gif [2]: /embed/inline-graphic-2.gif [3]: /embed/inline-graphic-3.gif [4]: /embed/inline-graphic-4.gif
New Auto-Hemolytic Disease Detected
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Update: Hantavirus Pulmonary Syndrome— United States, 1993
Journal: JAMA (1993)

A unique hantavirus has been identified as the cause of the outbreak of respiratory illness (hantavirus pulmonary syndrome [HPS]) first recognized in the southwestern United States in May 1993. The habitat of the principal rodent reservoir for this virus, Peromyscus maniculatus (deer mouse), extends throughout most of the United States except the Southeast. Through October 21, 1993, HPS has been confirmed in 42 persons reported to CDC from 12 states (Figure 1). This report summarizes major clinical, pathologic, and diagnostic findings in patients with this newly recognized syndrome; addresses the use of the investigational antiviral drug ribavirin; and presents revised screening criteria for national surveillance.
Drug-Resistant Fungus Arrives in US
Journal: JAMA (2017)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Mind-body medicine epigenetic technique (MET) and p53 gene expression.
Authors: Francisco Ventura Munoz
Journal: Journal of Clinical Oncology (2015)

e12507 Background: This pilot study is an exploration of the potential of MET to up-regulate p53 gene expression down-regulated by NF-kB gene expression in patients diagnosed with breast cancer. Methods: The selection process for the study participants was nonrandom. The following was the eligibility criteria. 1. Inclusion Criteria: Breast Cancer, Stages II, III. 2. Exclusion Criteria: Cognitively impaired, weak or ill. The pilot study utilized two groups. Each group was assigned two participants. Group One received one session of MET. Group Two received two sessions of MET. Each MET session was approximately 25-35 minutes in duration. Blood samples were taken at baseline and post-MET sessions to provide evidence in gene expression changes. For Group Two, the post-MET session blood draw was done 7 days after baseline. 1. Primary Endpoint: To determine whether MET can up-regulate p53 gene expression. 2. Secondary Endpoint: To determine whether there is a correlation between up-regulated NF-kB gene expression and down-regulated p53 gene expression. The blood samples were sent to genomics labs at the Children’s Hospital of Los Angeles and the University of Nevada Las Vegas for mRNA extraction and microarray analysis. The gene expression was measured by DNA microarrays using the “PrimeView gene chip” and “Partek Genomics Suite” statistical software. Results: For two participants, there were no statistical or biologically significant changes in gene expression. However, one participant from Group 1 evidenced a biologically significant down-regulation of NF-kB gene expression but no up-regulation of p53 gene expression. One participant from Group 2 evidenced biologically significant up-regulation of p53 gene expression but also evidenced the up-regulation of NF-kB gene expression. One major limitation of these findings is the statistical insignificance of the results due to the small number of participants. Conclusions: This pilot study evidenced the up-regulation of p53 gene expression potentially due to MET but no correlation between the down-regulation of NF-kB gene expression with the up-regulation of p53 gene expression. This pilot study provided a foundation of data and experience to conduct a larger study with more participants.
New Technique for Assay of Anticonvulsant Compounds
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Dairy consumption, systolic blood pressure, and risk of hypertension
Journal: BMJ (2017)

GESUS, DESIR, DCH Study, DIOGENES, PREDIMED-VALENCIA, and BPRHS cohorts were part of the CHARGE consortium.There were also some errors in the consortium names in the figures, which have also been corrected.In figure 1 Nutrition and Health of Ageing Population in China should have been called the Chinese cohort, the PREDIMED study should have been PREDIMED-VALENCIA, and the Family Health Study should have been Family Heart Study (FamHS).In figure 2 and 4 the Malmo study should be MDCS, FHS should be FamHS, PREDIMED should be PREDIMED-VALENCIA, and INCH should be InCHIANTI.In figure 3 the sixth study should be Drouin-Chartier (2014) and the final study should be Drouin-Chartier (2015).In figures 5 and 6, the Family Health Study should be FamHS, the PREDIMED study should be PREDIMED-VALENCIA, and Boston should be BPRHS.
Malignant granuloma.
Journal: BMJ (1969)

but achieved this greater duration of sleep by means of naps which were longer than naps taken on working days.5Wakefulness merges into sleep along a continuum, and as we drift towards sleep we fail to perform as efficiently and take longer to respond to something which merits attention.Under five hours of sleep the previous night makes this tendency more marked,6 while absolute sleeplessness makes errors frequent on any prolonged task.7 Thirty hours without sleep will seriously impair performance on a 25-minute task requiring continuous observation' and causes intermittent very long reaction times, or " microsleeps."'The more prolonged the task the more obtrusive the failures.Most motorway drivers, even when not short of sleep, have noticed occasions of drowsiness.Even if the eyes are forcibly kept open, extreme imposed monotony can quickly cause sleep, especially if movement is restricted.9The frequent drifts towards drowsiness which accompany monotony are associated with the slow E.E.G. of drowsiness, and it is at moments of E.E.G. slowing that reaction time is very pro- longed.'0These brief naps are even more likely after alcohol, and an ordinary sleeping-pill, such as quinalbarbitone 200 mg., will increase such lapses during the following day for at least 14 hours after ingestion of the drug."Napping under appropriate circumstances can help restore us, but a nap at the wheel of a car can be disastrous.Lack of sleep, sedatives, alcohol, warmth, restricted movements, and monotony will increase the liability to a nap.Frequent breaks, with physical activity and other elements of novelty, will help ensure alertness..
Prenatal diagnosis of classical phenylketonuria by gene mapping
Authors: S. L. Woo
Journal: JAMA (1984)

CLASSICAL phenylketonuria (PKU) is caused by a deficiency of the hepatic enzyme phenylalanine hydroxylase and is a typical example of an inborn error of metabolism.<sup>1-3</sup>The normal metabolic pathway of the aromatic amino acid is shown in Fig 1. Deficiency of phenylalanine hydroxylase causes the accumulation of phenylalanine and phenylalanine metabolites to excessively high levels and a depletion of serum tyrosine.<sup>4</sup>Without early detection followed by rigid dietary correction during the first decade of life,<sup>5</sup>children with classical PKU will develop severe mental retardation. The disease is transmitted as an autosomal recessive trait and has a prevalence of about one in 10,000 births among whites.<sup>6</sup>It has also been estimated that one in 50 whites in the population is a carrier of the gene for the disease.<sup>7</sup> In many Western countries, neonatal screening for PKU by the Guthrie test<sup>8</sup>is mandated by law, and dietary intervention
Prevalence of self-reported cognitive dysfunction in breast cancer patients.
Authors: Heidi Skirbe, Gabriela Hohn, Paula Klein, Mary Ann Juliano, Jeremy Winell, Victoria Rosenwald, Susan K. Boolbol, Joanne Festa
Journal: Journal of Clinical Oncology (2013)

131 Background: In 2011 a series of four time-limited, psycho-educational workshops was conducted by a neuropsychologist at a major urban academic medical center, providing information, coping strategies, and resources to women who had been treated for breast cancer (BrCa) and who then sought cognitive treatment. Based on positive evaluations of these workshops, we assessed the prevalence of self-reported cognitive dysfunction in BrCa patients with the goal of expanding cognitive services to all affected cancer patients. Methods: The study was IRB approved. We surveyed a convenience sample of 50 BrCa patients in a single medical oncology waiting room over several weeks. Subjects completed a 16 item questionnaire assessing potential cognitive problems on a 4 point-scale. Results: Fifty patients completed the survey, of whom 46% were currently employed. Sixty-eight percent of respondents were currently receiving cancer treatment and of those, 61.8% had also received prior treatment. Conclusions: An unexpectedly large proportion of BrCa patients perceived cognitive difficulties that may have been compounded by fatigue and emotional dysfunction. Others may have failed to report cognitive difficulties, unaware of their onset. Quality of life of cancer patients is diminished by cognitive decline. The current data indicate a need for formal assessment and intervention programs that will identify patients with cognitive and emotional dysfunction and remediate the difficulties via workshops and therapy. Formal neuropsychological assessment and treatment resourcestargeting cognitive changes associated with cancer should be expanded to meet documented need. Further research will optimize the scheduling and structure of therapeutic interventions. [Table: see text]
Editorial board
Authors: Andrew Schachat, Henry Jampel, Douglas Miami, Roy Beck, James Tampa, Wiley Brandt Sacramento, I Chambers, Thomas Washington, Los Chang, Susan Day, San Francisco, William Freeman, La Jolla, Glenn Durham, Robert Seattle, Yoshiaki Wa, Ronald Madison, Richard Alan, Lewis Houston, Maureen Maguire Philadelphia, Steven Mccormick, New York, Joel Mindel, Arthur Mueller, David Musch, Ann Arbor, Steven Charlottesville, Joan O'brien, Denis O', Day Nashville, Roger Steinert Boston, Richard Stone Philadelphia, Alan Sugar, Andrea Mi, Lake Tongue, Rohit Oswego, Thomas Weingeist Iowa, Richard London, Veronica Doyle, Miranda Walker, Tom Juhasz, Richard Zorab Vp, Ophthalmic Knowledge, Hal Straus
Journal: Ophthalmology (2003)
COLLES' FRACTURE.
Authors: JNO. EPH. LINK
Journal: JAMA (1896)

I had kept no notes or reports of cases incident to the subject in hand until I determined to prepare a paper to be presented at this meeting; therefore I shall necessarily be somewhat limited in statistics, but hope in what I do by presenting a few typical cases to at least suggest an idea as food for thought.If I fail I hope you will pardon my presumption, and if I succeed that it may be registered as a merit of credit to the anatomic field of study, observation and labor.Deformity in all cases is either the result of vio- lence or muscular spasm from irritation, or both.In the case of Colles' fracture and other injuries of the wrist joint, this is indeed particularly so.Especially the progressive form from reflex irritation.