tbuckley/cabot-search huggingface dataset:
Hepatitis B Outbreak in a State Correctional Facility, 2000
Journal: JAMA (2001)

On March 31, 2000, acute hepatitis B was confirmed serologically in a 34-year-old man (index patient) who had been incarcerated for 2.5 years at a high-security state correctional facility and who presented to the facility medical unit with jaundice and abnormal liver enzymes. He reported having unprotected sex with his cellmate as his only risk factor for infection during the 6 months preceding his illness. Serologic testing of the 21-year-old cellmate confirmed that he had chronic hepatitis B virus (HBV) infection. He reported no history of symptoms compatible with hepatitis and was previously unaware of his chronic infection, but he did report having unprotected sex with the index patient and two additional inmates in the dormitory (dorm Y). On May 15, 2000, the state's department of health and department of corrections and CDC initiated an investigation to identify additional cases and determine risk factors for HBV infection. This report summarizes the results of the investigation, which identified additional cases of HBV infection in this correctional facility and underscores the need to implement hepatitis B vaccination in correctional facilities.
In the Spotlight: Cardiovascular Engineering
Authors: N. Trayanova
Journal: IEEE Reviews in Biomedical Engineering (2008)

This article reviews the development of patient-specific image-based models of the heart and the circulatory system. The goal of these types of models is to provide better assessment of cardiovascular function under the patient-specific pathophysiological conditions and to serve as a testbed for improved cardiovascular therapies that are tailored to the patient. These new models constitute a part of the growing trend towards the development of new computational approaches (i.e., computational medicine) that can aid treatment and prevention of human disease.
Pork Insulin
Authors: JOHN A. GALLOWAY
Journal: Annals of Internal Medicine (1981)

Letters and Corrections1 October 1981Pork InsulinJOHN A. GALLOWAY, M.D.JOHN A. GALLOWAY, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-95-4-522 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: I wish to comment on the article "U-500 Insulin in the Treatment of Antibody-Mediated Insulin Resistance," by Nathan and colleagues(1). The authors describe three patients with immunologic resistance whose insulin dose was significantly reduced when the patients were treated with U-500 pork neutral regular insulin (NRI). In none of the cases presented was there a clear comparison of U-500 pork with U-100 (NRI) pork insulin, which we think would have been equally efficacious.For many years my colleagues and I have advocated the use of pork regular insulin for patients with immunologic resistance (2-4). The basis for...References1. NATHANAXELRODFLIERCARR DLJD. U-500 insulin in the treatment of antibody-mediated insulin resistance. Ann Intern Med. 1981;94:653-6. LinkGoogle Scholar2. BRESSLERGALLOWAY RJ. Insulin treatment of diabetes mellitus. Med Clin N Am. 1971;55:861-76. CrossrefMedlineGoogle Scholar3. GALLOWAYBRESSLER JR. Insulin treatment in diabetes. Med Clin N Am. 1978;62:663-80. CrossrefMedlineGoogle Scholar4. GALLOWAY J. When the patient is resistant or allergic to insulin. Med Times. 1980;108:91. MedlineGoogle Scholar5. AKREKIRTLEYGALLOWAY PWJ. Comparative hypogylcemic response of diabetic subjects to human insulin or structurally similar insulins of animal source. Diabetes. 1964;13:135-43. CrossrefMedlineGoogle Scholar6. GALLOWAYSPRADLINNELSONWENTWORTHDAVIDSONSWARNER JCRSJJ. Factors influencing the absorption, serum insulin concentration, and blood glucose responses after injections of regular insulin and various insulin mixtures. Diabetes Care. 1981;4:366-76. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Lilly Research Laboratories Indianapolis, IN 46202 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byInsulins for Insulin ResistanceDAVID M. NATHAN, M.D., LLOYD AXELROD, M.D. 1 October 1981Volume 95, Issue 4Page: 522-523KeywordsInsulinInsulin resistancePatient advocacy Issue Published: 1 October 1981 PDF downloadLoading ...
THE MYOBLASTOMA
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Study Indicates Utility for New Breast Cancer Prognostic Marker
Authors: J. Stephenson
Journal: JAMA (2001)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
DISABILITY INSURANCE AND HOSPITALIZATION PAYMENTS
Journal: JAMA (1942)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Diagnostic value of the colchicine therapeutic trial
Authors: S. I. Wallace
Journal: JAMA (1967)

The reliability of the colchicine therapeutic trial as a diagnostic tool in differentiating acute gout from other forms of arthritis was tested in this study. Rigid criteria for improvement as a result of colchicine therapy were established: (1) major subsidence of objective joint inflammatory changes within 48 hours of colchicine therapy, and (2) no recrudescence of inflammatory joint manifestations within seven days. Approximately 75% (44 of 58) of patients with acute gout responded in this manner; three of 62 (5%) patients with other arthritic disorders also responded. It is concluded that the colchicine therapeutic trial is a useful, but not infallible, diagnostic aid.
Minimum information needed by prescribers.
Authors: R Snaith
Journal: BMJ (1978)

tricyclic and, if that should fail, of an MAO inhibitor.I have been impressed with the good response of about half of these very severely affected patients to such therapy.Elithorn' stated that migraine is "undeniably a hunting-ground for the drug-happy physician."This, of course, is true, but such a statement should not deter efforts to find an effective treatment for this distressing and persistent disorder.
Analysis of glucocorticoid receptors in human hepatocellular carcinoma and HepG2 cells
Authors: W Lui
Journal: Hepatology (1993)

Hepatocellular carcinoma is the leading cause of male cancer death in Taiwan. We have found that the level of glucocorticoid receptor in hepatocellular carcinoma is significantly higher than that in the peritumoral tissue. In this study, we used a rat liver glucocorticoid receptor complementary DNA probe to examine the expression of glucocorticoid receptor gene in 15 paired samples of hepatocellular carcinoma and their peritumoral tissues. No differences in genomic DNA patterns of the glucocorticoid receptor gene were found between the tumor and peritumoral tissues. The amount of glucocorticoid receptor was found to be significantly higher in hepatoma samples than in peritumoral liver samples. The levels of glucocorticoid receptor messenger RNAs were increased in most tumors compared with their peritumoral samples. To examine the function of glucocorticoid receptors in hepatoma, we examined the expression of glucocorticoid receptor and its relation to cell-cycle progression in human HepG2 cells. Using specific monoclonal antibodies and flow cytometric study, we found glucocorticoid receptor to be expressed constitutively in all cell-cycle phases. In addition, hydrocortisone treatment of HepG2 cells resulted in increased expression of glucocorticoid receptors and increased secretion of α-fetoprotein. RU-486, a glucocorticoid antagonist, blocked the hydrocortisone effect, indicating that glucocorticoid receptors are functional in HepG2 cells. Taken together, our data suggest that glucocorticoids and their receptors play an important role in the growth of hepatoma. (HEPATOLOGY 1993;18:1167-1174).
365 Days
Authors: Alister Brass
Journal: JAMA (1971)

Three hundred and sixty-five days is the time each American soldier must spend in Vietnam to fulfill his contract. Dr. Glasser, who worked as a pediatrician in a large US military hospital in Japan, tells the stories of some of these men, and through their experiences (all real, he assures us) builds up a devastating picture of what that year is like. The locus of the book is the frantically busy hospital, to which wounded troops are evacuated. The facilities were superb, and the results of surgery magnificent, even allowing for the exceptional resilience of the young patients. Yet, "after a while it all began to seem so natural, the blind 17-year-olds stumbling down the hallway, or the shattered high school football player being wheeled to physical therapy." Even the "new psychiatry" with its phenomenal success in getting soldiers back to the war had its dubious aspects. There was no
Trial Validates Biosimilar for Trastuzumab
Journal: Cancer Discovery (2016)

Preliminary data from the phase III Heritage trial suggest that a biosimilar to trastuzumab, MYL-14010, is just as safe and effective as its brand-name equivalent for women with HER2-positive advanced breast cancer. The findings, presented during the annual meeting of the American Society of Clinical Oncology in June, may pave the way for the first FDA-approved biosimilar for cancer.
Guillain-Barré Syndrome and Bell's Palsy in Hawaii in 1981
Authors: Jack Brondum
Journal: JAMA (1984)

<h3>To the Editor.—</h3> We have reviewed the article entitled "Simultaneous Outbreaks of Guillain-Barré Syndrome and Bell's Palsy in Hawaii in 1981"<sup>1</sup>and have a few comments about the methods used in control selection. Proper control selection is of paramount importance for some of the serological comparisons made in this article. Unfortunately, the reader is left questioning how the childhood and adult control groups were actually selected. The reader is given no assurances that selection biases were not introduced. The Lilienfelds<sup>2</sup>and Sackett and Whelan<sup>3</sup>discuss the possible introduction of biases with controls selected from an unrepresentative population. What percentage of the childhood control subjects had disorders that produced immunodeficiency? Persons selected as controls with underlying conditions may not respond to antigenic challenges to agents such as cytomegalovirus or herpesviruses. This could help explain the differences in titer results between case and control populations. The author states that
RICKETS AND VITAMIN D
Journal: JAMA (1930)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
QOLP-18. PSYCHOLOGICAL INTERVENTION APPLIED TO MINIMIZING THE USE OF SEDATIVES IN 3–14 YEARS OLD CENTRAL NERVE SYSTEM TUMORS UNDERGOING RADIOTHERAPY
Authors: Lin Bo Cai, Xing Zhang
Journal: Neuro-Oncology (2018)

This article describes the application evaluation of psychological interventions in 3–14 years old central nerve system tumor children undergoing radiotherapy, furthermore, to promote optimal psychological interventions for local Chinese children. Between January 2016 and November 2017, 166 children patients received radiotherapy in Department of Oncology, Guangdong 999 Brain Hospital, 53 children(33 boys and 20 girls) of them with medical fear. Therefore, the medical team conducted psychological interventions to them before radiotherapy. Specially designed psychological intervention program included: Psychological scales, medical games, psychologists participated in the whole course of radiotherapy. The nurse recorded the usage of sedatives and heart rate, and the radiotherapist calculated the positioning setup errors. Psychological interventions worked successfully with 45(85%) children behaved cooperative (without showing any resistances by crying and screaming) at first radiotherapy and keeping still until the session was completed. For the aged 3-year-old group, 64%(7/11) children was successfully behaved cooperative; 4-year-old children in the success rate of 77%(10/13); 5 and 6-year-old children in the success rate of 100%(16/16);7-year-old children in the success rate of 80%(4/5). above 8-year-old children in the success rate of 100%. For those failed cases, 1 child used anesthesia during the whole radiotherapy sessions; 6 children were take sedatives from the first to third session of radiotherapy. There is a notable efficiency of psychological interventions for children diagnosed with CNS tumor across the radiotherapy trajectory. Children, parents and clinical decisions preferred psychological intervention methods. Further research is required to strengthen the evidence base for psychological interventions in minimizing the use of anesthesia
Endoscopic Diagnosis
Authors: John F. Morrissey
Journal: JAMA (1973)

In the past years, the endoscopist was limited to the use of rigid or flexi-rigid open-tipped esophagoscopes; the information that he was able to add in the diagnosis of esophageal malignancy to what had been obtained from a barium meal esophagram and a lavage cytology was often disappointingly small. Angulation and fixation of the esophagus often prevented visualization of the lesion; few endoscopists were able to obtain biopsies showing malignancy from more than 50% of tumors. The introduction of flexible forwardviewing fiberoptic endoscopes, which were 65 cm to 77 cm long, greatly improved this situation.<sup>36-38</sup>These instruments had short controllable tips that permitted easy passage through the esophagus in all patients except those with very tight strictures. The automatic controls for air, water, and suction provided a clear field in the presence of food, mucus, or even active bleeding. Adequate light for both visualization and photography were provided by
Health care prices, 1950-1967. Discussion of trends and their significance
Authors: E. M. Craft
Journal: JAMA (1968)

The recent publicity that has followed the increase in health care prices prompts the need for a concise statement on their trends and significance. During the period 1950-1965, health care prices increased more than any other major component in the "Consumer Price Index" (66.6%). During the same period, physicians' fees increased each year with the average annual increase ranging from a high of 4.4% in 1952 to a low of 2.2% in 1963. In 1966, physicians' fees experienced an increase of 5.8% followed by an Increase in 1967 of 7.1%. The main cause of rising health care prices has been the industry's inability to satisfy expanding consumer demand. The dynamic nature of the economy, plus necessary financial considerations, have placed certain limitations on the CPI as an instrument for measuring changes in price levels. Despite these limitations, however, it is the most widely accepted indicator of price movements.
REPORTS OF OFFICERS
Journal: JAMA (1930)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
In this issue
Authors: Ezzie Hutchinson, Kristine Novak, Nicola Mccarthy, Lesley Cunliffe, Jenny Bangham, Oliver Childs, Claudia Bentley, Emma Green, Art Controller, Nicola Hawes, Susanne Harris, Judith Shadwell, Deputy Production, Simon Fenwick, Luisa Estanislao, Sheryl Ocampo, Amanda Ward, Catherine Alexander, Puja Kamdar, Christina Large, Alexander Thurrell, Amy Wagner, Annette Thomas, Hugh Blackbourn, Jenny Henderson, Tony Rudland, Philip Campbell, Fabien Savenay, Anna Duguid, Kelly Lane, James Mcquat, Yvonne Strong, Natalie Smith, Stephen Schwartz, Ben Crowe, Sara Girard
Journal: Nature reviews. Cancer (2005)
The Phases of Scientific Truth
Journal: JAMA (1987)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal