tbuckley/cabot-search huggingface dataset:
Follow-up of schoolchildren in the vicinity of a coal-fired power plant in Israel.
Authors: A I Goren, J R Goldsmith, S Hellmann, S Brenner
Journal: Environmental Health Perspectives (1991)

This study was carried out in the framework of a health monitoring system set up in the vicinity of a 1400 megawatt coal-fired power plant in Israel. Second- and fifth-grade school children were followed up every 3 years; they performed pulmonary function tests (PFT), and their parents filled out American Thoracic Society-National Heart and Lung Institute health questionnaires. Among the cohort of second graders (in 1983) living in the area expected to be most polluted, a significant increase in the prevalence of part of the respiratory symptoms (such as cough and sputum, wheezing with and without cold and wheezing accompanied by shortness of breath) was evident in 1986. The prevalence of asthma among fifth graders in this area doubled (p = 0.0273) compared with prevalence when they were second graders. Among the children from the older cohort (fifth graders in 1983) living in this community, a similar although milder trend could be observed, especially in regard to an increased prevalence of asthma in 1986 compared with 1983 (13.9% versus 8.1%). Annual increases in PFT in the four groups of children (boys and girls from both cohorts) were found to be higher in the community expected to be polluted (especially in the younger cohort) compared with the two other communities. The discrepancy between the increased prevalence of respiratory symptoms and diseases and the higher annual increase in PFT among children from the expected more polluted community may be partly attributable to differential annual increase in height and to different distribution of background variables (such as socioeconomic status, passive smoking, heating, and respiratory diseases among parents) in the three communities.
在唇部疾病分类中深度学习等同于皮肤科医生
Authors: S.I. Cho, S. Sun, J. Mun, C. Kim, S.Y. Kim, S. Cho, S.W. Youn, H.C. Kim, J.H. Chung
Journal: British Journal of Dermatology (2020)

唇癌相对少见,但早期诊断是获得良好结局的重要因素。不幸的是,许多患者的诊断都有延误。一种新的机器学习方法,深度卷积神经网络 (DCNN),使用了据报道可以用于皮肤病分类的算法,其标准与委员会认证皮肤科医生的标准相同。然而,该方法还没有在嘴唇、头皮和生殖器等部位进行验证。 使用 DCNN 对恶性(癌)和良性(非癌)唇部疾病进行分类,并对其表现进行评价。这项研究中的影像来自韩国首尔国立大学医院 (SNUH) 的图片数据库。为了验证结果,从另外两家附属医院收集了额外的影像。总共使用了 1973 张来自 SNUH 的唇部影像,其中 853 例是恶性的,1120 例是良性的。 用 1629 张影像 (743 张恶性影像,886 张良性影像) 对 DCNN 进行了训练,并分别使用包含 344 张影像和 281 张影像的测试集和外部验证集来评估其表现。为了进行比较,要求 44 名接受过不同程度训练的参与者对影像进行分类。 研究发现,在对恶性肿瘤进行分类时, DCNN 的表现与皮肤科医生相当,优于非皮肤科医生。当非皮肤科医生参考 DCNN 的结果时,他们的表现要好得多。 因此, DCNN 可以用来按照相当于委员会认证皮肤科医生的标准对唇部疾病进行分类,它们可以帮助没有经验的医生区分唇部良性和恶性疾病。因此,DCNN 可以用来改善那些疑似唇癌患者的诊断和相应的患者预后。 本摘要涉及研究: 使用深度卷积神经网络对恶性唇部疾病进行皮肤科医生水平的分类
Aspirin is best for mild atrial fibrillation in primary care
Journal: BMJ (1999)

Behavioural counselling in primary care leads to improvements in health behaviour Behavioural counselling in primary care leads to greater improvements in health behaviour than standard health education and advice in patients at increased risk of coronary heart disease.Previous studies of health promotion and lifestyle counselling in primary care have produced disappointing results.Steptoe et al (p 943) found in a randomised trial that brief behavioural counselling on the basis of the "stage of change" model stimulated greater reductions in dietary fat intake and number of cigarettes smoked, and greater increases in physical activity than did usual care.The results suggest that behavioural counselling in primary care may be a useful strategy in the prevention of coronary heart disease.
Lectures on Certain Mutual Relations of Physiology, Pathology, and the Practice of Medicine
Authors: A. T. H. Waters
Journal: BMJ (1864)

The following is the forinula of the sedative mixture.R. Tincturie digitalis, tinoture cannabis Indicw, liquoris opii (Taylor), wtheris chlorici, singulorurm unciam.Dose 3as to 3j.+ Unfortunately
MEDICAL ASPECTS OF "BOOTLEG" LIQUORS
Journal: JAMA (1925)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Reduction of Bacteriuria and Pyuria Using Cranberry Juice
Authors: Roger Goodfriend
Journal: JAMA (1994)

<h3>To the Editor.</h3> —The article by Dr Avorn and colleagues<sup>1</sup>is flawed. The conclusions of this article are flawed because all urine samples were taken from "elderly women," and they were all voided specimens. What the authors may have been measuring is the bacteria present in the vaginal flora. As a urologist in practice for several decades, I have seen hundreds of elderly women in whom the treating physician was unable to "cure her infection." Invariably, they were assessing voided specimens of urine. When a specimen was obtained by catheter, the infection magically disappeared. It is virtually impossible to obtain a proper "clean-voided specimen" from an elderly female, especially if she is somewhat obese. There is an extremely high incidence of vaginal contamination. I have learned to start with a voided urine sample; if it shows bacteriuria, I will then get a catheterized urine sample. The evidence for bacteriuria
Policy recommendations expected from meeting on unintentional injuries in adolescents
Authors: V. S. Cowart
Journal: JAMA (1988)

ADOLESCENTS ARE a unique patient population in the United States. And, because an estimated 55% to 79% of all deaths in this age group are the result of injuries, the American Medical Association (AMA) recently sponsored a conference in Chicago on unintentional injuries in adolescents. Alan Engelberg, MD, MPH, director of the AMA's Department of Public Health, says this conference is the first step in producing specific recommendations for national public policy directed at preventing injuries in adolescents. Since the conference, the AMA's Council on Scientific Affairs has decided to focus on three topics. The first is whether trauma systems are meeting special adolescent needs. Second will be a statement of what constitutes a "mature minor" for the sake of giving consent to medical treatment. The third topic is how adolescents react to serious injuries or deaths among their peers. (Engelberg says there are no guidelines for schools to follow
TYPHOID FEVER AND WATER SUPPLIES.
Journal: JAMA (1893)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 2237: Detection of <i>CK-19</i> mRNA positive CTCs, isolated with a size-based microfluidics platform, in NSCLC patients under osimertinib therapy
Authors: Aliki Ntzifa, Athanasios Kotsakis, Vassilis Georgoulias, Evi Lianidou
Journal: Cancer Research (2019)

Abstract Background: Patients with EGFRmt non-small cell lung cancer (NSCLC) and resistant to first and second generation EGFR tyrosine kinase inhibitors (EGFR TKIs), receive therapy with osimertinib (third generation EGFR TKI). However, some patients experience resistance to osimertinib and disease progression. Molecular characterization of circulating tumor cells (CTCs) could offer great advantages as a non-invasive approach for disease monitoring. In this study, we isolated CTCs using a label-independent microfluidic-based platform to elucidate resistance mechanisms in these NSCLC patients. Materials and methods: Peripheral blood (PB) (15mL) was obtained at different time points from 27 patients with advanced NSCLC under osimertinib therapy. CTCs were isolated using the ParsortixTM system (ANGLE, Plc) and further harvested in Trizol reagent, followed by extraction of total RNA and cDNA synthesis. RT-qPCR was performed for CK-19 and B2M (used as a reference gene) mRNA in the COBAS z480 system (Roche Diagnostics). Results: PB samples were obtained at baseline (n=25), after one cycle of treatment with osimertinib (n=23), every 3 months (n=83) and at disease progression (PD) (n=16). CK-19 positive CTCs were detected in 3/25(12%) baseline samples, 24/83(28.9%) during treatment at different time points; 5/23(21.7%) after one cycle of treatment, 8/23(34.8%) after 3 months, 3/17(17.6%) after 6 months, 4/12(33.3%) after 9 months, 1/2(50%) after 12 months, 3/5(60%) after 15 months; and 5/16(31.2%) at PD. Conclusions: CK-19 mRNA-positive CTCs were isolated using an epitope-independent enrichment microfluidic device. Further molecular characterization of these cells at the gene expression, DNA mutation, DNA methylation and miRNA level will provide biomarkers for the elucidation of resistance mechanisms in NSCLC patients treated with osimertinib. Citation Format: Aliki Ntzifa, Athanasios Kotsakis, Vassilis Georgoulias, Evi Lianidou. Detection of CK-19 mRNA positive CTCs, isolated with a size-based microfluidics platform, in NSCLC patients under osimertinib therapy [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 2237.
Medicare Payments
Authors: Tracy Hampton
Journal: JAMA (2006)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Rebound Insomnia
Authors: Anthony Kales
Journal: JAMA (1979)

Five benzodiazepine drugs (diazepam, flunitrazepam, flurazepam hydrochloride, nitrazepam, and triazolam) were evaluated separately in 15 sleep laboratory studies. Rebound insomnia, a worsening of sleep compared with baseline, occurred following withdrawal of triazolam, nitrazepam, and flunitrazepam after they had been given in only single, nightly doses for short periods. The rebound insomnia was attributed to the short and intermediate half-lives of these drugs. Diazepam and flurazepam, which have longer half-lives, did not cause rebound insomnia on withdrawal. Rebound insomnia may play a role in the development of hypnotic drug dependence with shorter-acting benzodiazepine drugs. (<i>JAMA</i>241:1692-1695, 1979)
Accuracy of immunization histories provided by adults accompanying preschool children to a pediatric emergency department
Authors: K. P. Goldstein
Journal: JAMA (1993)

<h3>Objective.</h3> —Because some have advocated the use of emergency departments to administer delayed childhood immunizations, we evaluated the accuracy of immunization histories obtained in this setting by comparison with medical records of inner-city health care facilities. <h3>Design.</h3> —Questionnaires were orally administered to adults accompanying children to the emergency department. Individual medical records were reviewed. <h3>Setting.</h3> —Pediatric emergency department at Wyler Children's Hospital, University of Chicago and 68 inner-city primary care clinics. <h3>Patients.</h3> —Children aged 3 to 65 months registering for medical care. Of the sample, 98% were African American; 75% were Medicaid recipients. <h3>Main Outcome Measures.</h3> —Adults' knowledge of immunization histories, immunization cards, and medical records compared with American Academy of Pediatrics/Immunization Practices Advisory Committee recommendations. <h3>Results.</h3> —Of the accompanying adults, 64% stated that their child's<i>general</i>/immunization status was "up-to-date"; 65% of these had clinic records confirming that status. Only 8% of<i>specific</i>regimens stated by these adults accurately matched those found in clinic records. Moreover, 45% of adults accompanying children at least 16 months and older provided inaccurate information regarding previous receipt of measles immunization. <h3>Conclusion.</h3> —Information provided by accompanying adults (from recall or from immunization cards) is inadequate to determine accurately which preschoolers in the pediatric emergency department are delayed in immunizations. (<i>JAMA</i>. 1993;270:2190-2194)
Physiologic and Therapeutic Action of Light.
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Transferable Residues from Dog Fur and Plasma Cholinesterase Inhibition in Dogs Treated with a Flea Control Dip Containing Chlorpyrifos
Authors: J. Scott Boone, John W. Tyler, Janice E. Chambers
Journal: Environmental Health Perspectives (2001)

We studied chlorpyrifos, an insecticide present in a commercial dip for treating ectoparasites in dogs, to estimate the amount of transferable residues that children could obtain from their treated pets. Although the chlorpyrifos dip is no longer supported by the manufacturer, the methodology described herein can help determine transferable residues from other flea control insecticide formulations. Twelve dogs of different breeds and weights were dipped using the recommended guidelines with a commercial, nonprescription chlorpyrifos flea dip for 4 consecutive treatments at 3-week intervals (nonshampoo protocol) and another 12 dogs were dipped with shampooing between dips (shampoo protocol). The samples collected at 4 hr and 7, 14, and 21 days after treatment in the nonshampoo protocol averaged 971, 157, 70, and 26 microg chlorpyrifos, respectively; in the shampoo protocol the samples averaged 459, 49, 15, and 10 microg, respectively. The highest single sample was about 7,000 microg collected at 4 hr. The pretreatment specific activities in the plasma of the dogs were about 75 nmol/min/mg protein for butyrylcholinesterase (BChE), and 9 nmol/min/mg protein for acetylcholinesterase (AChE). BChE was inhibited 50-75% throughout the study, and AChE was inhibited 11-18% in the nonshampoo protocol; inhibition was not as great in the shampoo protocol. There was no correlation (p<or= 0.05) between length of hair and residues measured that would explain the residue differences among dogs. Transferable residues had largely dissipated during the three weeks after treatment, with the largest decrease occurring during the first week. Greater plasma ChE inhibition was observed at 7 days than at 4 hr, probably reflecting the bioactivation of chlorpyrifos to chlorpyrifos-oxon. Plasma cholinesterase activity did not return to control levels during the 3-week period. The differences between the shampoo and nonshampoo protocols were explained by differences in the techniques of the dip applicators.
THE DECREASING FREQUENCY OF TYPHOID FEVER.
Journal: JAMA (1898)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Deaths
Journal: JAMA (1970)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Medical Education, Registration and Hospital Service
Journal: JAMA (1928)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal