tbuckley/cabot-search huggingface dataset:
Relationship of Dietary Iodide and Drinking Water Disinfectants to Thyroid Function in Experimental Animals
Authors: Nathaniel W. Revis, Paul McCauley, George Holdsworth
Journal: Environmental Health Perspectives (1986)

The importance of dietary iodide on the reported hypothyroid effect of drinking water disinfectants on thyroid function was investigated. Previous studies have also showed differences in the relative sensitivity of pigeons and rabbits to chlorinated water. Pigeons and rabbits were exposed for 3 months to diets containing high (950 ppb) or low (300 ppb) levels of iodide and to drinking water containing two levels of chlorine. Results showed that the high-iodide diet prevented the hypothyroid effect observed in pigeons given the low-iodide diet and chlorinated drinking water. Similar trends were observed in rabbits exposed to the same treatment; however, significant hypothyroid effects were not observed in this animal model. The factor associated with the observed effect of dietary iodide on the chlorine-induced change in thyroid function is unknown, as is the relative sensitivity of rabbits and pigeons to the effect of chlorine. Several factors may explain the importance of dietary iodide and the relative sensitivity of these species. For example, the iodine formed by the known reaction of chlorine with iodide could result in a decrease in the plasma level of iodide because of the relative absorption rates of iodide and iodine in the intestinal tract, and the various types and concentrations of chloroorganics (metabolites) formed in the diet following the exposure of various dietary constituents to chlorine could affect the thyroid function. The former factor was investigated in the present studies. Results do not confirm a consistent, significant reduction in the plasma level of iodide in rabbits and pigeons exposed to chlorinated water and the low-iodide diet. The latter factor is being investigated.
Electrolyte games for rainy afternoons
Authors: L. B. Berman
Journal: JAMA (1975)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Cancer Risk from Asbestos in Drinking Water: Summary of a Case-Control Study in Western Washington
Authors: Lincoln Polissar, Richard K. Severson, Edwin S. Boatman
Journal: Environmental Health Perspectives (1983)

We conducted a case-control, interview-based study of the risk of developing cancer from asbestos in drinking water. An area that included Everett, Washington, was selected for the study because of the unusually high concentration of chrysotile asbestos in drinking water from the Sultan River. Through a population-based tumor registry, 382 individuals with cancer of the buccal cavity, pharynx, respiratory system, digestive system, bladder, or kidneys, diagnosed between 1977 and 1980, were identified, and they or their next of kin were interviewed. We conducted validation checks of our interviews, including a comparison with secondary sources. Data on asbestos exposure were collected based on residence and workplace history, and on individual water consumption. Logistic regression was used to estimate cancer risk. We found no convincing evidence for increased cancer risk from imbibed asbestos. Confidence intervals for relative risks for almost all sites included unity. There were significantly elevated risks only for male stomach and male pharyngeal cancer, but these sex-inconsistent results, based on small numbers of cases, are probably due to other factors.
Pathology
Authors: Martin Swerdlow
Journal: JAMA (1972)

The current edition of this standard work in pathology, edited by Dr. Anderson, has been thoroughly updated, surprisingly so for such a large text. It is generally well written, clear, and understandable. The illustrations vary in quality from fair to good and the references after each chapter are well chosen, appropriate, and well categorized. It is exceedingly difficult to review such a work; in reality it is many texts. There are 45 authors, 42 chapters, and two volumes. With respect to content, style, and clarity of objectives, this book is not of uniform quality throughout. Not all the authors appear to share common sets of goals and objectives. Since this may be inherent in any multiauthor work, my remark is intended as a perception, not a value judgment. The central question that I would raise is, for whom was this book written? The preface suggests that it is intended "to
Updated Hodgkin's disease. Comment: the reclassification of Hodgkin's disease
Authors: P. Rubin
Journal: JAMA (1972)

Cooperationking is a major factor in increasing survival rates in Hodgkin's disease. Undisciplinary management of Hodgkin's disease is no longer acceptable; the "old style" tumor board where specialists competed for cases is moving toward "staging conferences." The internist, radiation therapist, surgeon, diagnostic radiologist, and pathologist carefully assess the findings and jointly decide upon treatment. The definition of stage of disease is meaningful in determination of the sequence of therapeutic steps and in the reporting of end results. For these reasons, the remainder of this comment will deal with the reclassification of Hodgkin's disease that was developed in Ann Arbor, Mich in 1971 and presented publicly in St. Louis, Mo, from Oct 7 to 9,1971, at an informational symposium on Hodgkin's disease sponsored by the Cancer Clinical Investigation Review Committee of the National Cancer Institute.<sup>74</sup>The old classifications are presented in Fig 1 and Table 8<sup>1, 75-77</sup>; some considerations
THE RELATION BETWEEN PNEUMONIA AND PULMONARY TUBERCULOSIS.
Journal: JAMA (1900)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Correction
Journal: Circulation (1998)

sentence 2 under the subheading of "Participants" under the heading "Methods" on page 1785 should have appeared as follows:"Briefly, individuals were eligible for inclusion if they had a history of myocardial infarction or hospitalization for unstable angina 3 months to 3 years before enrollment and if they had a total serum cholesterol level between 4 and 7 mmol/L (155 to 271 mg/dL) after 2 months on a low fat diet (target Ͻ30% kJ from fat)."
Physicians and health policy
Authors: P. E. Dans
Journal: JAMA (1980)

HEALTH policy involves decisions on the allocation of manpower, services, and finances to meet patient care, education, and research needs. Physicians venturing into policy analysis are not usually conversant with these issues, nor are they familiar with the workings of the governmental bodies and other organizations responsible for health policy formulation. It seems to be assumed that if one is a first-rate researcher or clinician, the transition will be an easy one. Too often, this assumption is erroneous. Moreover, administration and policymaking generally are held in low esteem by both practicing and academic physicians. These activities require a partial or complete withdrawal from the one-on-one patient setting and involve concerns with systems and aggregate decision making. Physicians taking on such responsibilities are viewed as rejecting the raison d'être of medicine and becoming politicians. This position may have been credible once, "but the times, they are a-changin'." All physicians must have
Vaccination Coverage Among Children Entering School—United States, 2005-06 School Year
Journal: JAMA (2006)

One of the national health objectives for 2010 is to sustain > or =95% vaccination coverage among children in kindergarten through first grade (objective 14-23). To determine the percentage of vaccination coverage among children entering kindergarten, data on vaccination coverage were analyzed from reports submitted to the National Immunization Program by states, the District of Columbia (DC), and eight current or former U.S. territories for the 2003-04 school year. This report summarizes the results of that analysis, which determined that coverage for all vaccines except hepatitis B (HepB) and varicella was reported at >90% in 45 areas. However, the vaccines required in each reporting area and the methods for surveying kindergarten-aged children vary substantially; in seven states, <20% of eligible children were surveyed. The wide variations in survey populations underscore the need for CDC to continue working with immunization programs in states, DC, and current or former territories to improve survey methods and automate reporting of data.
Surgical Complications
Authors: Tracy Hampton
Journal: JAMA (2005)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Ulcerating Pustules
Authors: Kirstin Altman, Molly A. Hinshaw
Journal: JAMA Dermatology (2014)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Dermatology HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Dermatology journal
Breast cancer and thyroid therapy. Statement by the American Thyroid Association
Authors: C. A. Gorman
Journal: JAMA (1977)

IT HAS recently been reported<sup>1</sup>that, among patients undergoing mammography at a hospital in Detroit, the prevalence of breast cancer was higher in women receiving thyroid hormone therapy than in those who were not. Prevalence of breast cancer was said to increase with increasing duration of thyroid hormone treatment, particularly in nulliparous women. Since the time that this report appeared and was widely publicized by the news media, many patients have expressed concern that the thyroid hormone they are taking may be dangerous, and they have inquired as to whether such treatment should be stopped. The American Thyroid Association, whose membership comprises physicians and basic scientists interested in the thyroid and its diseases, views the aforementioned article with concern, both because of its implication of a possible basic relationship between thyroid therapy and breast cancer and because of its potential impact on the treatment of patients who require thyroid
Global phase 3, randomized, double-blind, placebo-controlled study evaluating PEGylated recombinant human hyaluronidase PH20 (PEGPH20) plus nab-paclitaxel and gemcitabine in patients with previously untreated, hyaluronan (HA)-high, stage IV pancreatic ductal adenocarcinoma (PDA)
Authors: E. Van Cutsem, A. Hendifar, M. Reni, L. Zheng, M. Ducreaux, W. Harris, P. Corrie, T. Seery, D. Chondros, A. Bullock
Journal: Annals of Oncology (2017)
Commentary
Authors: Peter D. Siersema
Journal: Endoscopy (2020)

In Billroth II gastrectomy, the remaining proximal stomach is anastomosed to the proximal jejunum. When performing ERCP in Billroth II anatomy, endoscopists face several technical challenges. Although traditionally conventional side-viewing duodenoscopes or forward-viewing gastroscopes were used, single- or double-balloon enteroscopy has been shown to ease ERCP in complicated reconstruction anatomy. Recently, endoscopic ultrasound (EUS)-guided gastrojejunostomy (GJ)-assisted ERCP has been introduced, which is the topic of this E-Video.
Synthesis and Radiolabeling of Heterocyclic Food Mutagens
Authors: Henry Rapoport, Andrew L. Waterhouse, Charles M. Thompson, John F. O'Connell
Journal: Environmental Health Perspectives (1986)

The imidazoquinoline and imidazoquinoxaline food mutagens found in cooked meat are being synthesized by unambiguous methods that allow for the preparation of sufficient quantities of material for biological studies. These methods avoid difficult separations of regioisomeric mixtures of products and are designed to allow incorporation of specific high level tritium labeling.
Books Received
Journal: JNCI Journal of the National Cancer Institute (1972)

Journal Article Books Received Get access Dorsey EV: So I Had Breast Cancer and How Are You?Jericho, N.Y., Exposition Press, Inc., 1972, 78 pp, $4.00. Knox WE: Enzyme Patterns in Fetal, Adult and Neoplastic Rat Tissue. Basel, Switzerland, S. Karger, 1972, 354 pp, $22.30. Oncology (Clark RL, Cumley RW,McCay JE, et al, eds.). Chicago, Year Book Medical Publishers, Inc., $139.50. British Empire Cancer Campaign: Annual Report, London. International Cancer Congress, 10th, Houston, Tex., 1970 (Clark RL, et al, eds.). Chicago, Year Book Medical Publishers [c1971], $135.50. International Symposium on the Treatment of Carcinoma of the Prostate, Berlin, 1969 (Raspé G., Brosig W eds.). Oxford, N.Y., Pergamon Press, 1971, 209 pp, $16.00. International Symposium onVirology and Immunology of Human Tumors, Tokyo, 1970 (Nakahara W. et al, eds.). Tokyo, Univ. of Tokyo Press, Baltimore, Univ. Park Press, 1971, 590 pp, $34.50. Lang EK: The Roentgenographic Diagnosis of Renal Mass Lesions. St. Louis, Green [c1971], 182 pp. Motlík K.: Ovarian Neoplasms; Morphology and Classification. Praha, Universita Karolova [c1970], 366 pp, $1.80. National Conference on Breast Cancer, 2d, Los Angeles, 1971. Philadelphia, Lippincott, 1971, pp 1361–1727. Survey of Compounds Which Have Been Tested for Carcinogenic Activity: Bethesda, Md., National Cancer Institute, $7.00. UICC Latin American Regional Conference on Cancer Control, Santiago de Chile, 1967. Geneva, International Union Against Cancer, 1968, 91 pp, $2.00. Vsesoiuznyî simpozium po probleme leîkozov (leukemia congresses) (Kiselev AE, ed.). Riga, 1971, 382 pp. JNCI: Journal of the National Cancer Institute, Volume 48, Issue 5, May 1972, Page 1553, https://doi.org/10.1093/jnci/48.5.1553 Published: 01 May 1972
Erratum: Sall1 is a transcriptional regulator defining microglia identity and function
Authors: Anne Buttgereit, Iva Lelios, Xueyang Yu, Melissa Vrohlings, Natalie R Krakoski, Emmanuel L Gautier, Ryuichi Nishinakamura, Burkhard Becher, Melanie Greter
Journal: Nature Immunology (2017)
Tuberculosis as a manifestation of the acquired immunodeficiency syndrome
Journal: JAMA (1986)

<h3>To the Editor.—</h3> The frequency of diagnosed<i>Mycobacterium tuberculosis</i>infection in the acquired immunodeficiency syndrome (AIDS) is escalating. The recent article by Sunderam et al<sup>1</sup>raises interesting issues regarding the relationship of these two diseases.<i>Mycobacterium tuberculosis</i>infection was shown in their study to have severe and unusual manifestations, with overwhelming extrapulmonary disease. The lack of an intact T-cell immune response in AIDS has been the commonly accepted explanation.<sup>1</sup>However, the enhanced suppressor cell activity common to both infections may play a role in the pathogenesis of these simultaneously occurring diseases. T-cell lymphopenia with a decrease in the T-helper/suppressor cell ratio occurs in untreated patients with<i>M tuberculosis</i>infection and can be reversed with therapy.<sup>2</sup>Patients with<i>M tuberculosis</i>infection who demonstrate cutaneous anergy have enhanced suppressor cell activity. In vitro, once suppressor cells are depleted, there is a 24-fold increase in T-lymphocyte response to purified protein
Neurilemmomatosis
Authors: Y. MURATA, K. KUMANO, K. UGAI, A. IJICHI, K. TAOMOTO, M. TANI
Journal: British Journal of Dermatology (1991)

Journal Article Neurilemmomatosis Get access Y. MURATA, Y. MURATA Departments of Dermatology, Hyogo Medical Center for Adults, Akashi, Japan Dr Y.Murata, Hyogo Medical Center for Adults. 18–70 Kitaoji‐cho, Akashi 673, Japan. Search for other works by this author on: Oxford Academic Google Scholar K. KUMANO, K. KUMANO Departments of Dermatology, Hyogo Medical Center for Adults, Akashi, Japan Search for other works by this author on: Oxford Academic Google Scholar K. UGAI, K. UGAI Departments of Orthopaedics Hyogo Medical Center for Adults, Akashi, Japan Search for other works by this author on: Oxford Academic Google Scholar A. IJICHI, A. IJICHI Departments of Neurosurgery Hyogo Medical Center for Adults, Akashi, Japan Search for other works by this author on: Oxford Academic Google Scholar K. TAOMOTO, K. TAOMOTO Departments of Neurosurgery Hyogo Medical Center for Adults, Akashi, Japan Search for other works by this author on: Oxford Academic Google Scholar M. TANI M. TANI Department of Dermatology, Kobe University School of Medicine, Kobe, Japan Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 125, Issue 5, 1 November 1991, Pages 466–468, https://doi.org/10.1111/j.1365-2133.1991.tb14775.x Published: 01 November 1991
The Croonian Lectures on Functional Derangements of the Liver
Authors: C. Murchison
Journal: BMJ (1874)

Remarks.2. A Dficient Suppply of Oxygen.--Insufficient muuscular exercise in lhe open air may derange the functions of the liver.It is well known that sedentary habits and confinement in badly ventilated rooms tend to induce derangements of the liver.It is also a common observation that persons w-%ho have eateni and drunk too freely have not suffered from their livers so lonig as they have led an active life in the open ail ; but that, as sooni as from chanige of occupation, or other causes, they take to sedentary habits, without any corresponding change in diet, derange- ment of the liver ensues.Again, every sportsman who has suffered from hepatic derangement knows the effect of a single day's hunting or shooting in clearing his complexion and relieving his symptoms.A want of regular exercise in the open air leads to derangement of the liver in twN,o ways; viz., a, by causing a deficient supply of oxygen to the * "Vires qute sanguinis per hepar motum accelerant."
BALDNESS BREAKTHROUGH
Authors: None Goldsmith
Journal: JAMA (1965)

A glimmer of hope has come to a long suffering segment of our population who silently and painfully endure the mental agonies of common baldness. Man's earliest fallout problem has, through the ages, established the balding individual as a prime candidate for jibes, jokes, and cruel exploitation. More fortunate contemporaries fight their own fears, which have a broad foundation of folklore and superstition, with comforting quips such as, "The only thing that stops falling hair is— the ground" or the equally well-known, "The best way to save your hair is—in a cigar box." The humor is lost to the victim who is aware of the profound mental and physical hardships which may accompany the loss of this otherwise unnecessary filamentary adornment. Younger men and women of any age are particularly struck by their personal misfortune. The inevitable process is equated with loss of vigor and aging. Compelled, at last, in
Jejunoileal bypass: pass it by
Authors: C. B. Clayman
Journal: JAMA (1981)

Morbid obesity is defined as 100% or more above the ideal body weight, although no uniform definition has been accepted by all concerned. It is a disease that is associated with accelerated degeneration of important organ systems and a diminished quality of life and self-image.<sup>1,2</sup>Society often treats the condition with disdain, repulsion, or amusement and the victim as a freak. Acceptance of evidence that survival is decreased in this condition resulted in the development of jejunoileal (J-I) bypass. More recent data question impairment of survival in the absence of such risk factors as hypertension, diabetes, or hyperlipidemia.<sup>3</sup>Even more alarming is the number of serious complications that are associated with this procedure as it has found widespread use in many hospitals. The reports elsewhere in this issue (pp 970, 982) are only the latest in a long list of debilities or disorders produced by the effects of