tbuckley/cabot-search huggingface dataset:
Family Medicine
Authors: Marjorie A. Bowman
Journal: JAMA (1997)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Bioavailability of Inorganic Arsenic from Bog Ore-Containing Soil in the Dog
Authors: Kees Groen, Huub A. M. G. Vaessen, Jan J. G. Kliest, Jan L. M. de Boer, Ton van Ooik, Arie Timmerman, Ron F. Vlug
Journal: Environmental Health Perspectives (1994)

In some parts of The Netherlands, bog ore-containing soils predominate, which have natural arsenic levels that exceed, by a factor of 10, existing standards for maximum allowable levels of inorganic arsenic in soil. These standards are based on the assumption that in humans the bioavailability of arsenic from ingested soil is equal to that from an aqueous solution. In view of the regulatory problem that the arsenic levels of these soils present, we questioned the validity of this assumption. To obtain a more realistic estimate, the bioavailability of inorganic arsenic from soil in a suitable animal model was studied. In this report, a study performed in six dogs in a two-way cross-over design is presented. The dogs received orally, in random order, arsenic both as an intravenous solution and as arsenic-containing soil. During a 120-hr period after administration urine was collected in 24-hr fractions. Levels of arsenic were determined using a method of wet digestion, isolation and complexation of arsine, followed by molecule absorption spectrometry. Within 120 hr after intravenous administration, 88 +/- 16% of the dose was excreted renally. After oral administration of arsenic-containing soil, only 7.0 +/- 1.5% was excreted renally. From the urinary excretion data for these two routes of administration, the calculated bioavailability of inorganic arsenic from soil was 8.3 +/- 2.0%. The results from this study demonstrate the need to reconsider the present risk assessment for arsenic in soil.
Modified FOLFOXIRI (mFOLFOXIRI) plus cetuximab (cet), followed by cet or bevacizumab (bev) maintenance, in RAS/BRAF wt metastatic colorectal cancer (mCRC): The phase II randomized MACBETH trial by GONO
Authors: C. Cremolini, C. Antoniotti, F. Loupakis, F. Bergamo, L. Ferrari, R. Grande, G. Tonini, G. Masi, M. Schirripa, M. Bonotto, C. Soldà, S. Lucchesi, D. rossini, D. Corsi, M. Ronzoni, F.L. Rojas Llimpe, G. Fontanini, L. Boni, V. Zagonel, A. Falcone
Journal: Annals of Oncology (2016)
THAT THE CAT HAD CUT ITS FOOT ON A BROKEN BOTTLE WILL ALWAYS BE DOUBTFUL
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Sir Thomas Lewis (1881-1945) experimental cardiologist
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Smokers' Polycythemia
Authors: J. Robert Smith, Stephen A. Landaw
Journal: New England Journal of Medicine (1978)

Twenty-two smokers with elevated hematocrits (mean, 54 per cent) had elevated blood carboxyhemoglobin (mean, 11.6 per cent; normal, less than 1 per cent) and a "left-shifted" oxygen-hemoglobin dissociation curve (mean P50, 21.6±2.3 [± S.D.] torr; normal, 26.7±1.1). Red-cell volume was increased in 14 of 18, and plasma volume reduced in 14 of 18. Fatigue and headache were common, and syncopal attacks occurred in four patients. Symptoms disappeared and the elevated red-cell volume decreased markedly in all five patients who were able to reduce severely their smoking habit; low plasma volume increased in three of four patients studied. We conclude that carbon monoxide exposure from cigar and cigarette smoke is a frequent cause of an elevated red-cell volume or a reduced plasma volume (or both). Measurement of carboxyhemoglobin should be a routine part of the evaluation of all polycythemic subjects. (N Engl J Med 298:6–10, 1978)
Acta Orthopaedica Scandinavica, Copenhagen
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Diving Accident Network begins 2nd year
Authors: P. Gunby
Journal: JAMA (1981)

Recently, a scuba diving student in Texas made what appeared to be a normal ascent after about 15 minutes at 7.5 m below the water's surface. But then he lost consciousness and began having convulsions. After it was determined that there were gas bubbles in the pericardium and other tissues, the diver was rushed by military helicopter to Brooks AFB, San Antonio, some 130 km away, where there is a hyperbaric chamber (<i>JAMA</i>[MEDICAL NEWS] 1981; 246:1057-1066; 1171-1178). After treatment there as well as in a civilian hospital's chamber, the patient appeared to regain most functions and was enrolled in physical therapy. Later, in response to a news reporter's question, Maj Luis A. Matos, MC, USAF, a medical officer at Brooks, commented: "People who scuba dive should know the location of the nearest hyperbaric chamber so they can receive treatment, should they ever need it, as quickly as possible." That
Anesthesiology
Authors: M. Jane Matjasko
Journal: JAMA (1989)

The American Board of Anesthesiology was 50 years old in 1988. More than 16000 certificates have been awarded to physicians who now represent the fourth generation of anesthesiologists in the United States. In 1988, it was estimated that there were 5000 anesthesiologists in training. New pharmacologic agents include esmolol hydrochloride, an ultrashort-acting parenteral β-blocker; propofol, an intravenous induction agent with rapid recovery and little or no hangover; and flumazenil, a benzodiazepine antagonist. Esmolol, with a half-life of 9 minutes, has been used effectively to control undesirable hypertensive and tachycardiac responses in the perioperative period, particularly in patients with cardiac and intracranial disease processes.<sup>1,2</sup>Potential exacerbation of myocardial ischemia, of cerebral edema, or of intracranial hypertension related to the hyperdynamic state associated with laryngoscopy or emergence from anesthesia can be effectively and safely managed within 2 to 3 minutes by injection of a loading dose followed by an infusion of
Bilateral Anterior Tibial Claudication
Authors: Brian M. Kennelly
Journal: JAMA (1968)

Fasciotomy relieved symptoms of claudication in both anterior tibial muscle compartments in two otherwise healthy adolescent patients. Effective blood flow in the muscles before surgery, measured with sodium chloride Na 22 clearance, was impaired after the patients had exercised, while intramuscular pressures in the anterior tibial compartments, measured by saline manometry, remained elevated for a longer than normal time following exercise. These results were compared with those found in two previously reported cases in which the patients were tested in this way.
Arterial and Venous Thrombosis in Monoclonal Gammopathy of Undetermined Significance and Multiple Myeloma: A Population-Based Study.
Authors: Sigurdur Y Kristinsson, Ruth Pfeiffer, Magnus Bjorkholm, Lynn R Goldin, Sam Schulman, Cecilie Blimark, Ulf-Henrik Mellqvist, Anders Wahlin, Ingemar Turesson, Ola Landgren
Journal: Blood (2009)
Ethylene Oxide and Leukemia
Authors: Raymond R. Neutra
Journal: JAMA (1987)

<h3>To the Editor.—</h3> Divine and Amanollahi<sup>1</sup>argue that the study of Hogstedt and associates<sup>2</sup>—which confirmed an earlier observation that workers occupationally exposed to ethylene oxide had elevated rates of leukemia mortality—was seriously deficient. They also cite a previous occupational study,<sup>3</sup>involving a larger cohort, that found no excess cancer mortality. We address the issue of the carcinogenicity of ethylene oxide by comparing dose-response data from animals<sup>4</sup>with human data.<sup>2,3</sup> Ethylene oxide produced mononuclear cell leukemia in both male and female rats in two separate inhalation bioassays.<sup>4,5</sup>Thus, animals and humans of both sexes develop cancer in the same type of tissue after ethylene oxide exposure. <h3>Study.—</h3> We examined how well the dose-response relationship observed in rats fitted the epidemiologic data from several cohorts.<sup>2,3</sup>Our objective was to see if the observed number, of human cancer deaths was in the range of what
Duodenal Ulcer: The Present Status of Definitive Surgery; The Selection and Management of Patients Undergoing Operation
Authors: John R. Brooks, Francis D. Moore
Journal: New England Journal of Medicine (1959)

A LTHOUGH duodenal ulcer, like so many other disorders, may be said to occupy a spectrum of severity, there is a very impressive contrast between patients whose symptoms are easy to control and those who appear to defy virtually all measures. Furthermore, the former patients may in the course of time become transformed into those for whom surgical treatment is difficult. They start out with a disease whose treatment lends itself to temporization and procrastination by patient and doctor alike. Often, there is no compelling need for aggressiveness. Gradually, as the years go by, the patient becomes a progressively less . . .
Medical Milestones At..
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Cancer Staging
Authors: Samuel Vaisrub
Journal: JAMA (1978)

The noise that time makes in passing by Is very light but even you can hear it. Merrill Moore—<i>The Noise That Time Makes</i> What time is it? All it takes is a quick look at the timepiece, and the simple question receives a simple, direct answer. This simplicity, however, is deceptive. Neither the question nor the answer tells us anything about the abstract time of mathematical physics, the biologic time of rhythmic organic functions, or the cyclic rhythms of historical time. Nor does it relate to the subjective time manifest in the human mind. The swinger who has "the time of his life" and the criminal who is "doing time" have different perceptions of time, which do not reflect the temporal dimension measured by the clock. The temporal dimension is one of the physician's major concerns. Time is suspended when life and death brush against each other in
RJR Nabisco's cartoon camel promotes camel cigarettes to children
Authors: J. R. DiFranza
Journal: JAMA (1991)

<h3>Objectives.</h3> —To determine if RJR Nabisco's cartoon-theme advertising is more effective in promoting Camel cigarettes to children or to adults. To determine if children see, remember, and are influenced by cigarette advertising. <h3>Design.</h3> —Use of four standard marketing measures to compare the effects of Camel's Old Joe cartoon advertising on children and adults. <h3>Subjects.</h3> —High school students, grades 9 through 12, from five regions of the United States, and adults, aged 21 years and over, from Massachusetts. <h3>Outcome Measures.</h3> —Recognition of Camel's Old Joe cartoon character, product and brand name recall, brand preference, appeal of advertising themes. <h3>Results.</h3> —Children were more likely to report prior exposure to the Old Joe cartoon character (97.7% vs 72.2%;<i>P</i>&lt;.0001). Children were better able to identify the type of product being advertised (97.5% vs 67.0%;<i>P</i>&lt;.0001) and the Camel cigarette brand name (93.6% vs 57.7%;<i>P</i>&lt;.0001). Children also found the Camel cigarette advertisements more appealing (<i>P</i>&lt;.0001). Camel's share of the illegal children's cigarette market segment has increased from 0.5% to 32.8%, representing sales estimated at $476 million per year. <h3>Conclusion.</h3> —Old Joe Camel cartoon advertisements are far more successful at marketing Camel cigarettes to children than to adults. This finding is consistent with tobacco industry documents that indicate that a major function of tobacco advertising is to promote and maintain tobacco addiction among children. (<i>JAMA</i>1991;266:3149-3153)
GENEVA
Journal: JAMA (1928)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Medical librarians
Authors: Tiago Villanueva, Balaji Ravichandran
Journal: BMJ (2006)

A medical career entails the constant pursuit of information. Helen Elwell explains how to make the most of the skills and knowledge of medical librarians Medical information is essential for patients' care, research, and when writing for publication. Increasingly though, this pursuit is becoming more challenging, requiring specialist skills. Evidence based medicine requires you to appraise critically the information you use to inform your clinical decision making. You will also need online searching skills to get the most out of the resources available on your computer. Added to all this is the fact that medical information is increasing at a phenomenal rate, making it easy to feel frustrated or pressurised. It is in this environment that a medical librarian can step in and give you the support you need. LPWoods A number of different types of support are on offer. A librarian is not only an information expert, able to advise on best resources, but also a trainer and a service provider. Medical librarians have good credentials, and so armed with a few tips you will be able to make better use of their help. Medical librarians are professionally qualified. They have either a graduate or a postgraduate qualification, which has been accredited by the Chartered Institute of Library and Information Professionals. The most common route is to have a postgraduate qualification. Typically, a medical librarian has an MSc, an MA, or a postgraduate diploma. You can expect the following range of services to be available whether you are at medical school, working for an NHS trust, or approaching a professional organisation such as the BMA or the Royal Society of Medicine:
Parathyroid Imaging
Authors: GARY G. WINZELBERG
Journal: Annals of Internal Medicine (1987)

Advances in diagnostic imaging methods during the last decade have facilitated the identification of focal or diffuse parathyroid abnormalities. Major advances have included improvements in computed tomography and high-resolution ultrasonography, and the introduction of thallium-201-technetium-99m parathyroid subtraction scintigraphy. The more invasive methods of venous sampling and selective angiography have also been refined, but they have not been used as extensively because of the need for highly skilled personnel. The role of these diagnostic tools before surgery in the routine evaluation of patients with suspected primary hyperparathyroidism is unclear because a skilled surgeon should be able to achieve cures in 90% of these patients during exploratory surgery. However, most physicians would agree that, in those patients whose abnormalities go undetected during exploratory surgery of the neck, diagnostic imaging methods should be used before additional surgery is planned. Further prospective studies are needed to determine if routine localization before surgery is cost effective.
PLoS Medicine Issue Image | Vol. 2(1) January 2005
Journal: PLoS Medicine (2005)

As his memory fades, the man in this image will lose his past as well as his present—where his beloved cat remains unfed. This drawing embodies the essence of my grandparents' last years. None had Alzheimer disease, but I often think of them as their bodies and minds were failing and how they would have felt as the precious parts of their lives disappeared. I have been working as a freelance illustrator for 25 years and have been an adjunct professor at the University of Michigan School of Art and Design since 1993. My process begins with sketching, then I draw and paint directly on my chosen surface. I'm influenced immensely by popular printed materials, especially posters and covers, magazines, and books. I strive to create realistic but off-beat scenes, and it's important to me that the work have a handcrafted look and lots of natural texture. Image Credit: W. C. Burgard (www.wcburgard.com)