tbuckley/cabot-search huggingface dataset:
The benefit of adjuvant treatment for resected locally advanced non-small-cell lung cancer. The Lung Cancer Study Group.
Journal: Journal of Clinical Oncology (1988)

The purpose of this trial was to investigate the impact of systemic combination chemotherapy on survival and recurrence patterns in incompletely resected non-small-cell lung cancer. Incomplete resection was defined as presence of residual tumor in the resection margin or by presence of metastasis in the highest paratracheal lymph node sampled during protocol-directed surgical staging of the mediastinum. One hundred seventy-two patients were randomized to receive either postoperative radiotherapy (RT) alone or postoperative RT plus chemotherapy with CAP (Cytoxan [cyclophosphamide; Bristol Myers, Evansville, IN], Adriamycin [doxorubicin; Adria Laboratories, Columbus, OH], and Platinol [cisplatin; Bristol Myers]) for 6 months. One hundred sixty-four patients were eligible for analysis at a mean time since randomization of 3.7 years. The chemotherapy arm showed significantly longer recurrence-free survival (two-sided Mantel-Haenszel log rank test, P = .004). This difference holds true for nonsquamous patients (P = .01), and approaches significance for squamous patients as well (P = .08). There was a 14% difference in survival rate favoring the chemotherapy arm 1 year after randomization. Analysis of sites of recurrence showed a significant decrease in distant metastases in the chemotherapy arm. Median survival for the entire group was approximately 17 months, and 35% are alive 2 years after resection. Toxicity of treatment consisted of esophagitis (mild-moderate by Eastern Cooperative Oncology Group [ECOG] criteria) and predictable hematologic, gastrointestinal (GI), and skin toxicity expected from CAP.
Transurethral Electrocautery Procedures in Patients With Cardiac Pacemakers
Authors: Richard L. Fein
Journal: JAMA (1967)

Three patients with cardiac pacemakers underwent four transurethral electrocautery procedures, without pacemaker interference. Electrical interference which could potentially cause cardiac arrhythmias was prevented by utilizing a well-shielded cardiac pacemaker, by proper grounding of all medical electronic equipment in use on or near the patient, and by keeping the electrocautery circuit below the pacemaker by low placement of the electrocautery ground plate. Additional safety precautions included maintenance of a normal blood volume and cardiac monitoring with an external pacemaker-defibrillator cardioscope.
THE MECHANISM OF THE LARYNGEAL PALSIES COMPLICATING TABES DORSALIS.
Journal: JAMA (1902)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
TB Picture Brightening, but Dark Spots Remain
Authors: B. Vastag
Journal: JAMA (2002)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abdominal Angina
Authors: Leon G. Berman, Francis R. Russo
Journal: New England Journal of Medicine (1950)

IN MOST syndromes, so-called classic pictures develop as a result of the more severe manifestations of the disease. As knowledge increases, lesser forms are recognized. This is illustrated best in the literature of recent years by the more frequent recognition of milder, subacute and recurrent types of pancreatitis as against the more classic severe catastrophe. Similarly, in textbooks the subject of intra-abdominal vascular disease is usually confined to a discussion of massive mesenteric thrombosis or embolism, with extensive infarction of the intestine, and gangrene and death in a high percentage of cases. Again, only in recent years has there been . . .
THE PROPOSED INTERNATIONAL CATALOGUE OF INCUNABULA
Journal: JAMA (2013)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Conference on Virology and Immunology in Human Cancer
Journal: JNCI Journal of the National Cancer Institute (1973)

Journal Article Conference on Virology and Immunology in Human Cancer Get access JNCI: Journal of the National Cancer Institute, Volume 50, Issue 6, June 1973, Page 1730, https://doi.org/10.1093/jnci/50.6.1730-a Published: 01 June 1973
Asepsable or Aseptizable.
Journal: JAMA (1893)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Interferon α therapy in children with chronic hepatitis B — prognostic factors and therapy tolerance
Authors: A. Liberek, G. Luczak, W. Bako, G. Sikorska, M. Rytlewska, A. Szlagatys-Sidorkiewicz, M. Góra-Gȩbka, Z. Bohdan, M. Korzon
Journal: Journal of Hepatology (2001)
Limitations of listing specific medical interventions in advance directives
Authors: A. S. Brett
Journal: JAMA (1991)

Recent events, including the Cruzan decision and the passage of the Patient Self-Determination Act, have renewed interest in the strengths and limitations of various types of advance directives. In one well-known approach, the competent person indicates preferences for or against a series of specific medical interventions that might be considered if the person loses decision-making capacity. However, such lists of interventions may shift attention away from overall treatment goals or may prescribe inappropriate medical care. Moreover, listing specific interventions in advance does not necessarily enhance self-determination or reduce uncertainty in decision making. (<i>JAMA</i>. 1991;266:825-828)
Oil Embolism in Lymphangiography: Incidence, Manifestations, and Mechanism
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Current Topics in Biostatistics and Epidemiology: A Memorial Symposium in Honor of Jerome Cornfield
Journal: JNCI Journal of the National Cancer Institute (1980)

Current Topics in Biostatistics and Epidemiology: A Memorial Symposium in Honor of Jerome Cornfield JNCI: Journal of the National Cancer Institute, Volume 65, Issue 5, November 1980, Page 1198, https://doi.org/10.1093/jnci/65.5.1198-e Published: 01 November 1980
SEQUELAE OF THE COMMUNICABLE DISEASES OF CHILDHOOD AS A PUBLIC HEALTH PROBLEM
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE VALUE OF PROPHYLAXIS AGAINST VENEREAL DISEASES
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Diagnostic tests are overused
Journal: BMJ (2002)

Some caution is needed in interpreting Cochrane reviewsCochrane reviews contain methodological and other weaknesses, in particular the over-rating by the reviewers in their conclusions of the benefits of new interventions.Olsen and colleagues (p 829) assessed the quality of a sample of 53 reviews first published in the Cochrane Library in 1998 and found major problems in 15.The evidence did not fully support the conclusion in nine reviews, the conduct or reporting was unsatisfactory in 12, and stylistic problems (such as errors in spelling or grammar) occurred in 12.The authors say that although the Cochrane Library remains a key source of evidence on the effects of health interventions, the reviews should be interpreted cautiously.
PWE-127 Restless Leg Syndrome, (RLS) is Associated with Hepatic Encephalopathy (He) in Decompensated Cirrhosis. A Clinical Pilot Study
Authors: P Basu, N J Shah, S Farhat, R Siriki, K Mittimanj, M Rahaman, S Atluri
Journal: Gut (2013)

<h3>Introduction</h3> RLS affects 10% of the general population, affecting the quality of life (QOL). Exact aetiology is still unknown. Iron deficiency, small intestinal bacterial overgrowth (SIBO) and inflammatory bowel disease (IBD) have clear association with RLS. Decompensated cirrhosis with portal hypertension has multi-organ involvement causing minimal and overt encephalopathy with sleep: dysnomia, parasomnia, and stupor which has clear association with Sub acute bacterial Peritonitis (SBP ) which has precipitating clinical state with SIBO, This clinical study evaluates the association of RLS in HE amongst decompensated cirrhotics. <h3>Methods</h3> One hundred eight (n = 108) patients were recruited. Group A (n = 36) decompensated cirrhotic (mean MELD 16, OHE 20/36(55%), MHE 16/36(44%), esophageal varices grade II 24/36(67%). Group B (n = 36) chronic liver disease- Alcohol 9/36(25%) NASH 12/36(33%) HCV 12/36(33%) HBV 1/36(3%) AIH 2/36(6%) with mean MELD 6).without cirrhosis Group C (n = 36) healthy controls. Initially all received Xifaxan 550mg orally twice daily for 10 days to eradicate co-existing SIBO. All underwent Methane breath test for SIBO. Baseline labs: Serum levels for renal function, ferritin, iron studies, haemoglobin/hematocrit, ammonia, celiac, and IBD serology, stool lactoferrin &amp; calprotectin and urine for toxicology screening. Groups A and B underwent neuro-psychometric and flicker testing for MHE and OHE and sleep testing for RLS (with Mayo RLS questionnaire). Exclusion: Chronic iron deficiency, Celiac, IBD, major depression, IBS, benzodiazepines, narcotics, alcohol, anti-psychotics and illicit drugs. <h3>Results</h3> Group A 24/36(67%) had RLS: [OHE 16/20 (80%), MHE 8/16 (50%), esophageal varices 8/10(80%), alcoholic cirrhotic 10/14(71%), CHC 3/6(50%), NASH 3/6 (50%) and SIBO 14/36 (39%)]. Group B 1/36(3%) RLS and SIBO 7/36(19%). Group C 2/36(6%) RLS and SIBO 3/36(8%). All confirmed by sleep study and RLS questionnaire. Serum ammonia has no impact on RLS. <h3>Conclusion</h3> This clinical trial postulates decompensated cirrhotics have high evidence of RLS with portal hypertension. Larger trials will validate. <h3>Disclosure of Interest</h3> None Declared.
ALCOHOL AND HYPOGLYCEMIC COMA
Journal: JAMA (1968)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Inflammation, not hyperhomocysteinemia, is related to oxidative stress and hemostatic and endothelial dysfunction in uremia
Authors: Diego Mezzano, Edgar O. Pais, Eduardo Aranda, Olga Panes, Patricio Downey, Mireya Ortiz, Rodrigo Tagle, Fernando Gonzalez, Teresa Quiroga, M. Soledad Caceres, Federico Leighton, Jaime Pereira
Journal: Kidney International (2001)
Availability of Applications for Public Health Leadership Institute
Journal: JAMA (1999)

Canada received reports from public health authorities in Alaska and the Yukon Territory about clusters of febrile respiratory illness and associated pneumonia among travelers and tourism workers.This report presents information about the outbreak.Laboratory evidence, including rapid influenza A antigendetection tests and viral cultures from respiratory specimens, has implicated influenza A virus as the cause of illness.As of June 29, CDC has received reports of 428 cases of acute respiratory infection (ARI) among tourists who traveled to Alaska and the Yukon Territory from May 22 through June 28 on seven separate week-long cruises.For 187 (48%) of the 386 ill persons whose dates of illness onset were known, illness occurred before or within 48 hours after boarding a cruise ship, suggesting that transmission occurred during a preceding land-based tour.The ARI incidence for the 386 cases was 3.8% among 10,110 passengers for a 7-day travel itinerary; the ARI attack rate was 5.5 per 1000 passenger-days.One hundred thirty-two (34%) cases met criteria for influenza-like illness (ILI) (i.e., fever or feverishness with cough or sore throat); four persons were hospitalized for pneumonia.No deaths have been reported.Among tourism workers, 104 cases of ARI have been reported.
The genetic origins of neoplasia
Authors: A. J. Levine
Journal: JAMA (1995)

The last 15 years have witnessed a conceptual breakthrough in our understanding of the molecular and genetic basis of the origins of neoplasia in humans. This happened methodically, experiment by experiment, with no one observation yielding the entire picture. Over time, a large number of observations slowly came together, and, for that reason, we often do not give enough credit to the science, or the scientists, for this remarkable achievement. Mutations in three broad categories of genes have been shown to contribute to the origins and progression of neoplasia in humans: the oncogenes, the tumor suppressor genes, and the mutator genes. Almost 100 different oncogenes have been identified in animals and humans and shown to contain mutations in a wide variety of tumors. Most of these oncogenes were discovered with the use of retro viruses that insert adjacent to an oncogene and activate it or capture the oncogene in a
Correction
Journal: BMJ (1963)

only 6% of babies being fed rigidly by the clock); the use of a dummy (about 70%); attitudes to and manage- ment of crying in the baby ; worries about genital play (the boy giving much more anxiety than the girl) ; the helpfulness, and unhelpfulness, of the father (only 39% bath the baby) ; breaks away from the baby; class differences in methods of infant feeding, toilet training, the management of sleep, and punishment.I feel it would have been better if the social differences in management had not been placed in a separate section but included under each of the problems dis- cussed.In other words, when discussing the attitudes to genital play I would have included the class differences-such as the fact that it was checked by 25 % of mothers in Social Class 1 and by 93 % in Class 5.Frankly I do not believe that only 82% of babies sucked their thumbs at one year-unless finger sucking and wrist sucking are excluded.Apart from this I think that an experienced paediatrician, interested in behaviour, would have successfully guessed the findings in every field, but it is most desirable that our clinical impressions should be confirmed by factual studies.I regard this book as a readable and valuable socio- logical study, in which paediatricians, family doctors, and any concerned with infant care will find much of interest.The authors deserve congratulations.
Leprosy
Journal: JAMA (1941)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal