tbuckley/cabot-search huggingface dataset:
THE M. O. L. L. U. S. AND ITS MEDICAL FOUNDERS.
Journal: JAMA (1890)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Bad genes
Authors: T. Greenhalgh
Journal: BMJ (1994)

<h3>ABSTRACT</h3> <h3>Introduction:</h3> Several countries have adopted integrated community case management (iCCM) as a strategy for improved health service delivery in areas with poor health facility coverage. Early implementation of iCCM is often run by nongovernmental organizations financed by donors through projects. Such projects risk failure to transition into programs run by the local health system upon project closure. Engagement of subnational health authorities such as district health teams (DHTs) is essential for a smooth transition. <h3>Methods:</h3> We used a repeated qualitative study design to assess the readiness of and progress made by DHTs in institutionalizing iCCM into the functions of locally decentralized health systems in 9 western Uganda districts. Readiness data were derived from structured group interviews with DHTs before iCCM policy adoption in 2010 and again in 2015. Progressive institutionalization achievements were assessed through key informant interviews with targeted DHT members and local government district planners in the same areas. <h3>Findings:</h3> In the readiness study, DHTs expressed commitment to institutionalize iCCM into the local health system through the development of district-specific iCCM activity work plans and budgets. The DHTs further suggested that they would implement district-led training, motivation, and supervision of community health workers; procurement of iCCM medicines and supplies; and advocacy activities for inclusion of iCCM indicators into the national health information systems. After iCCM policy adoption, follow-up study data findings showed that iCCM was largely not institutionalized into the local district health system functions. The poor institutionalization was attributed to lack of stewardship on how to transition from externally supported implementation to district-led programming, conflicting guidelines on community distribution of medicines, poor community-level accountability systems, and limited decision-making autonomy at the district level. <h3>Conclusion:</h3> Successful institutionalization of iCCM requires local ownership with increased coordination and cooperation among governmental and nongovernmental actors at both the national and district levels.
Epidemiology of new influenza A(H1N1) in the United Kingdom, April – May 2009
Authors: None Health Protection Agency and Health
Journal: Eurosurveillance (2009)

Following importations of cases from Mexico and the United States, by 11 May, United Kingdom surveillance activities had detected a total of 65 individuals with confirmed infections caused by the new influenza A(H1N1) virus. The infections were mainly in young people and younger adults and they spread within households and within schools. The illness in the United Kingdom is similar in severity to seasonal influenza and to date, besides one case of bacterial pneumonia, no clinically serious cases have occurred.
Highlights
Journal: JAMA (2018)

Algorithm-Based Therapy for Staphylococcal Bacteremia 1249Undertreated infections have lower cure rates, but overtreatment with antibiotics increases the likelihood of drug-related adverse events.Holland and colleagues for the Staphylococcal Bacteremia investigators randomized 509 patients with staphylococcal bacteremia and found that use of an algorithm to guide testing and treatment resulted in a noninferior rate of clinical success compared with usual care.In an Editorial, Perencevich and Malani suggest that antimicrobial stewardship programs and guidelines should consider the use of algorithms to set targets for the duration of antibiotic regimens.
Clinton's Health System Reform Proposal and Workforce Planning
Journal: JAMA (1994)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Erratum
Authors: Nov Letters, H Semon, D Snell, H Squires, W Sturrock, A Sutlift, W Sweet, P Talbot, C Tangye, R 'raylar, A Thomas, J Teesda, J Turnly, W Vevers, J Walker, J Warburton, C Watkins, A Willis, A Wrjght, George Freelandbarbour Simpson, Edinburgh Casrles, Mowbray Pearson, Edin- Burgh Aud, Edwin Matthew, Henry Grabham Lys, Charles Mackie Begg, John Yearsley, L Ir, C O'herlihy, K Kanga, V Walsh, D Ilckey, T Mckendrick, E Spence, A Kelsey, H Scott, A Livingston, R Flack, ).-J Bruggman, D O', ' Course, ).-E Porter, T Eames, S Dharples, J Mcmcurray, J Hlunter, Sarah Anna, Jane Lindsay, T Reddy, V Sanzgiri, C Stewart, B Davidson, A Taranurvalla, J Kiddle, F Reid, D Milne, P Anderson, Years Course) -E F Niven, Gertrude Austin, D Mac Be-Dallas, A Gunasekara, L Dias, F Murphy, J Rockwood, T Ferguson, E Dykes, R Smith, Examination.-W Final, C Scott, J Ring, F Collier, R Duncan, J Hosford, R Murphy, H Simpson, S Gettings, W Wertheim, J Coates, H Dixon, V Mcintosh, N Macdonald, E Simpson, J Raffel, G Coffey, E Beaton, M Murphy, J Desmond, P E ', Desai Titterton, T Chaubal, T Fliteroft, K Murphy, E Menon, J Dawes
Journal: BMJ (1905)
Shakespeare on the brain, Vivaldi on the weather, and Darwin on docu-soap?The Bard on the Brain: Understanding the Mind Through the Art of Shakespeare and the Science of Brain Imaging by Paul M. Matthews and Jeffrey McQuain, University of Chicago Press, 2003. E21.99/$35.00 (192 pages) ISBN 0 97238 302 6
Authors: B DEGELDER, N HADJIKHANI
Journal: Trends in Cognitive Sciences (2003)
The suitability of HIV-positive individuals for marriage and pregnancy
Journal: JAMA (1989)

<h3>To the Editor. —</h3> It is regrettable that in an otherwise thorough and thoughtful analysis of heterosexual transmission of human immunodeficiency virus (HIV) that Drs Haverkos and Edelman<sup>1</sup>conclude with incautiously worded comments on the future course of public debate and policy. They state that "societies may soon have to wrestle with many difficult questions, including the suitability of infected individuals for marriage and natural parenthood." The question of whether to mandate premarital screening for HIV infection has been debated in state legislatures across the nation. In virtually all cases, public health officials have argued that given the epidemiology of HIV disease, the patterns of sexual behavior in America, and the social costs of widespreadscreening, such an approach to prevention would represent a misguided effort. In Louisiana, a one-year trial of mandatory premarital screening has been ended. Whatever the justification for requiring testing so that potential marriage partners might
POLYMERSOMES
Authors: Dennis E. Discher, Fariyal Ahmed
Journal: Annual Review of Biomedical Engineering (2006)

Polymersomes are self-assembled polymer shells composed of block copolymer amphiphiles. These synthetic amphiphiles have amphiphilicity similar to lipids, but they have much larger molecular weights, so for this reason--along with others reviewed here--comparisons of polymersomes with viral capsids composed of large polypeptide chains are highly appropriate. We summarize the wide range of polymers used to make polymersomes along with descriptions of physical properties such as stability and permeability. We also elaborate on emerging studies of in vivo stealthiness, programmed disassembly for controlled release, targeting in vitro, and tumor-shrinkage in vivo. Comparisons of polymersomes with viral capsids are shown to encompass and inspire many aspects of current designs.
Pedestrian and hypothermia deaths among Native Americans in New Mexico. Between bar and home
Authors: M. M. Gallaher
Journal: JAMA (1992)

<h3>Objective.</h3> —To determine the nature of excess injury mortality among Native Americans in New Mexico. <h3>Design.</h3> —Retrospective review of death certificates for deaths from unintentional injuries. <h3>Setting.</h3> —The state of New Mexico. <h3>Subjects.</h3> —New Mexico residents who died of unintentional injuries between January 1, 1980, and December 31, 1989. <h3>Main Outcome Measure.</h3> —Cause-specific mortality rates. <h3>Results.</h3> —Over half of the excess mortality from all unintentional injuries among Native Americans resulted from hypothermia and from pedestrian—motor vehicle crashes. New Mexico Native Americans were nearly eight times more likely to die in pedestrian—motor vehicle crashes and were 30 times more likely to die of hypothermia compared with other New Mexico residents. At death, 90% of those Native Americans tested were highly intoxicated (median blood alcohol concentrations of 0.24 and 0.18 mg/dL for pedestrian and hypothermia deaths, respectively). Despite the fact that most Native Americans in New Mexico live on reservations, most deaths occurred at off-reservation sites in border towns and on roads leading back to the reservation. <h3>Conclusions.</h3> —The possession and sale of alcohol is illegal on many Native American reservations. This policy forces Native Americans who want to drink to travel long distances to obtain alcohol. These data suggest that this policy is also the likely explanation for the markedly increased risk of death from hypothermia and pedestrian—motor vehicle crashes in this population. (<i>JAMA</i>. 1992;267:1345-1348)
14 A DRUG TRANSPORTER GENE POLYMORPHISM PREDICTS RENAL TUBULAR TOXICITY IN PATIENTS WITH CHRONIC HEPATITIS B ON LONG-TERM ADEFOVIR AND LAMIVUDINE COMBINATION
Authors: M. Viganò, P. Lampertico, P. Dongiovanni, F. Facchetti, L. Valenti, R. Soffredini, S. Fargion, M. Colombo
Journal: Journal of Hepatology (2010)
Ursodiol for the long-term treatment of primary biliary cirrhosis Poupon RE, Poupon R, Balkau B. N Engl J Med 1994;330:1342?1347
Journal: Hepatology (1995)

Malformations of cortical development (MCD) represent a major cause of developmental disabilities and severe epilepsy. Advances in imaging and genetics have improved the diagnosis and classification of these conditions. Up to now, eight genes have been involved in different types of MCD. Lissencephaly-pachygyria and subcortical band heterotopia (SBH) represent a malformative spectrum resulting from mutations of either LIS1 or DCX genes. LIS1 mutations cause a more severe malformation in the posterior brain regions. DCX mutations usually cause anteriorly predominant lissencephaly in males and SBH in female patients. Additional forms are X-linked lissencephaly with corpus callosum agenesis and ambiguous genitalia associated with mutations of the ARX gene. Lissencephaly with cerebellar hypoplasia (LCH) encompass heterogeneous disorders named LCH types a to d. LCHa is related to mutation in LIS1 or DCX, LCHb with mutation of the RELN gene, and LCHd could be related to the TUBA1A gene.Polymicrogyria encompasses a wide range of clinical, etiological, and histological findings. Among several syndromes, recessive bilateral fronto-parietal polymicrogyria has been associated with mutations of the GPR56 gene. Bilateral perisylvian polymicrogyria has been associated with mutations in the SRPX2 gene in a few individuals and with linkage to chromosome Xq28 in a some other families.X-linked bilateral periventricular nodular heterotopia (PNH) consists of PNH with focal epilepsy in females and prenatal lethality in males. Filamin A (FLNA) mutations have been reported in some families and in sporadic patients. It is possible to infer the most likely causative gene by brain imaging studies and other clinical findings.
STATE MEDICAL SOCIETIES.
Journal: JAMA (1893)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Culture Clash
Authors: C. K. Wittenberg
Journal: JNCI Journal of the National Cancer Institute (1992)

Journal Article Culture Clash Get access Clarissa K. Wittenberg Clarissa K. Wittenberg Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 84, Issue 19, 7 October 1992, Page 1473, https://doi.org/10.1093/jnci/84.19.1473 Published: 07 October 1992
Author Correction: Blinatumomab in pediatric patients with relapsed/refractory acute lymphoblastic leukemia: results of the RIALTO trial, an expanded access study
Authors: Franco Locatelli, Gerhard Zugmaier, Noemi Mergen, Peter Bader, Sima Jeha, Paul-Gerhardt Schlegel, Jean-Pierre Bourquin, Rupert Handgretinger, Benoit Brethon, Claudia Rossig, Christiane Chen-Santel
Journal: Blood Cancer Journal (2021)

A Correction to this paper has been published: https://doi.org/10.1038/s41408-021-00413-7.
Postexposure Prophylaxis for Occupational Exposure to HIV
Authors: D. Bangsberg
Journal: JAMA (1999)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Temperature in Isolation Perfusion Chemotherapy
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A phase III study of receptor-targeted <sup>99m</sup>Tc-tilmanocept versus blue dye in the evaluation of SLNs in breast cancer and melanoma.
Authors: F. O. Cope, V. K. Sondak, A. M. Wallace
Journal: Journal of Clinical Oncology (2011)

LBA8526^ Background: Intraoperative lymphatic mapping (ILM) evaluation is widely used for staging clinically node-negative breast CA and melanoma. [ 99m Tc]Tilmanocept (TcT) is a novel CD206 receptor-targeted (intra-nodal CD206 + RE cells) radiopharmaceutical designed for ILM of nodes (LNs) with anatomic nexuses to the tumor bed. We report the results of a Phase III, multicenter trial designed to assess the ILM performance of TcT vs the approved standard, vital blue dye (VBD) in both melanoma and breast CA patients (pts). Methods: 8 centers provided 153 pts w/ 1 0 melanoma or breast CA (ECOG 0-2; T1-4, N0, M0). TcT (50 µg @ 0.5-1.0mC i 99m Tc) and VBD (per label) were injected to each pt; ILM was performed w/ a hand held γ-detector (for TcT) and visual eval (for VBD); all γ+ and blue+ LNs were excised and histologically examined. TcT was injected per study center practice (subareolar and intradermal injection w/ &gt;0.5 hr wait); VBD was injected at surgery. The 1 0 endpoints were concordance w/ TcT and VBD (% of LNs detected by VBD and identified by TcT) and reverse concordance (% LNs detected by TcT and identified by VBD); path +/- per localization of TcT and VBD were also assessed. Pts were assessed for lab safety and AEs. Results: (Table) VBD pts (standard ILM pt metric) who expressed ≥1 VBD + LN equate to the intent-to-treat (ITT) group. Conversely, the reverse ITT (RITT) group consisted of pts expressing ≥1 γ+ node. The analyses of the 1 0 endpoints are estimates of the 95% CIs. The 1 0 hypothesis is H 0 : R ≤0.90 vs H a : R &gt;0.90; R = concordance rate (2-sided, α = 0.05). Additional contrasts include tests for Δ residual disease (path) and effect on pt staging. Conclusions: The receptor targeted ILM agent, TcT, provided clinically superior results compared to label-approved VBD. TcT localization of occult disease was significantly improved vs VBD. The results suggest that receptor targeting of the lymphatic RE cells is a key development in ILM of LN metastasis. [Table: see text]
Gang-Related Outbreak of Penicillinase-Producing Neisseria gonorrhoeae and Other Sexually Transmitted Diseases—Colorado Springs, Colorado
Journal: JAMA (1993)

In April 1990, the El Paso County (Colorado) Health Department (EPCHD) recognized an outbreak of penicillinase-producing Neisseria gonorrhoeae (PPNG) and other sexually transmitted diseases (STDs) occurring in Colorado Springs (1990 census population: 397,014), Colorado. An investigation by the EPCHD and the Colorado Department of Health eventually identified 56 cases of PPNG from December 1989 through March 1991 (Figure 1). The outbreak revealed a previously unidentified core group of persons with STDs in Colorado Springs. This report summarizes traditional and innovative measures used to investigate and manage the outbreak, and describes this core group and its role in STD transmission in Colorado Springs.
Kidney transplantation in monozygotic twins discordant for lupus
Authors: S. M. Zonnebelt
Journal: JAMA (1981)

A 25-year-old man with renal failure secondary to systemic lupus erythematosus (SLE) received a kidney from his identical twin five years after onset of the first twin's symptoms of lupus. Both continue to do well. To our knowledge, there are no other reports of kidney transplantation in monozygotic twins discordant for SLE. (<i>JAMA</i>1981;245:68-69)
&lt;TITLE&gt;Procedures for Blocked Coronary Arteries&lt;/TITLE&gt;
Journal: JAMA (2000)

information and recommendations appearing on this page are appropriate in most instances, but they are not a substitute for medical diagnosis.For specific information concerning your personal medical condition, JAMA and the AMA suggest that you consult your physician.This page may be reproduced noncommercially by physicians and other health care professionals to share with patients.Any other reproduction is subject to AMA approval.
Myositis Ossificans Traumatica
Authors: Peter Jokl
Journal: JAMA (1977)

A case report of an outstanding college football halfback with partial factor XI deficiency, recurrent ecchymosis, and myositis ossificans is reviewed. The association of multiple areas of myositis ossificans and partial clotting-factor deficiency has not been noted in the past. The importance of considering this diagnosis in participants in contact sports with the above findings is emphasized. (<i>JAMA</i>237:2215-2216, 1977)
Categorizing, tracking birth abnormalities
Authors: P. Cotton
Journal: JAMA (1990)

THREE of four birth defects in this country are epidemiologic mysteries, says Godfrey Oakley, MD, chief of the birth defects branch in the CDC's Center for Environmental Health and Injury Control, Atlanta, Ga. "We don't know if we're looking for 50 [causes] or, my guess is, closer to 100 000 different disease processes," he says. "The challenge is to find these various and sundry causes," Oakley says, that together account for the fifth leading cause of years of potential life lost in the United States. Oakley keeps track of reported birth defects and mental retardation, putting them into 150 categories in all and analyzing the numbers every 6 months for any changes or emerging patterns. "So much is associated with nondescript poverty," he says, and lack of prenatal care is often blamed. But, Oakley says, he suspects the latter is "overrated" as a cause by itself. While incidence does go