Postmenopausal Hormone Replacement Therapy
Authors: Linda L. Humphrey, Benjamin K.S. Chan, Harold C. Sox
Journal: Annals of Internal Medicine (2003)

Letters15 April 2003Postmenopausal Hormone Replacement TherapyLinda L. Humphrey, MD, MPH, Benjamin K.S. Chan, MS, and Harold C. Sox, MDLinda L. Humphrey, MD, MPHOregon Health & Science University; Portland Veterans Affairs Medical Center; Portland, OR 97201 (Humphrey)Oregon Health & Science University; Portland, OR 97201 (Chan)American College of Physicians; Philadelphia, PA 19106 (Sox)Search for more papers by this author, Benjamin K.S. Chan, MSOregon Health & Science University; Portland Veterans Affairs Medical Center; Portland, OR 97201 (Humphrey)Oregon Health & Science University; Portland, OR 97201 (Chan)American College of Physicians; Philadelphia, PA 19106 (Sox)Search for more papers by this author, and Harold C. Sox, MDOregon Health & Science University; Portland Veterans Affairs Medical Center; Portland, OR 97201 (Humphrey)Oregon Health & Science University; Portland, OR 97201 (Chan)American College of Physicians; Philadelphia, PA 19106 (Sox)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-138-8-200304150-00029 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:We appreciate the opportunity to again discuss the limitations of the observational literature evaluating hormone therapy and CHD in women. Before the publication of the Heart and Estrogen/progestin Replacement Study in 1998, postmenopausal hormone therapy was widely recommended to women to prevent CHD, largely on the basis of data from observational studies. However, ascertainment of hormone therapy use in these studies was limited, as we discussed and described in Appendix Tables 1 and 2 of our paper. Very few studies evaluated the type of estrogen used, whether progestins were used, or the dose of either formulation. Despite limitations, ...Reference1. Humphrey LL, Nelson HD, Chan BK, Nygren P, Allan J, Teutsch S. Relationship between hormone replacement therapy, socioeconomic status, and coronary heart disease [Letter]. JAMA. 2003;289:45. CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Oregon Health & Science University; Portland Veterans Affairs Medical Center; Portland, OR 97201 (Humphrey)Oregon Health & Science University; Portland, OR 97201 (Chan)American College of Physicians; Philadelphia, PA 19106 (Sox) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoPostmenopausal Hormone Replacement Therapy and the Primary Prevention of Cardiovascular Disease Linda L. Humphrey , Benjamin K.S. Chan , and Harold C. Sox Postmenopausal Hormone Replacement Therapy Steven J. Meyerson Postmenopausal Hormone Replacement Therapy Arthur B. Chausmer Metrics 15 April 2003Volume 138, Issue 8Page: 688-689KeywordsCongenital heart diseaseEstrogen replacement therapyEstrogensHormonal therapyHormone replacement therapyHormonesNursesNursing educationObservational studiesSocioeconomic status ePublished: 15 April 2003 Issue Published: 15 April 2003 CopyrightCopyright © 2003 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...