tbuckley/cabot-search huggingface dataset:
Münchener Medizinische Wochenschrift
Journal: JAMA (1969)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
RUNX1 DNA-Binding Mutations and RUNX1-PRDM16 Cryptic Fusion in BCR/ABL+ Leukemias Are Frequently Associated with Secondary Trisomy 21 and May Contribute to Clonal Evolution and Imatinib Resistance.
Authors: Catherine Roche-Lestienne, Laureline Deluche, Selim Corm, Isabelle Tigaud, Sami Joha, Nathalie Philippe, Sandrine Geffroy, Jean-Luc Lai, Franck Nicolini, Claude Preudhomme
Journal: Blood (2007)
Transmission of infectious diseases in outpatient health care settings
Authors: R. A. Goodman
Journal: JAMA (1991)

Increased provision of health care in outpatient settings and concerns about occupational transmission of infections have focused attention on the risk of transmission of infectious diseases in ambulatory health care settings. In contrast to inpatient nosocomial infections, infections transmitted in outpatient settings are neither systematically monitored nor likely to be detected by routine qi surveillance. To better define the spectrum of such events, we reviewed the literature to identify cases and clusters of infections associated with outpatient health care. In this review, we identified and epidemiologically characterized 53 such reports that occurred from 1961 through 1990. Transmission occurred in general medical offices, clinics, and emergency departments (23); ophthalmologists' offices and clinics (11); dental offices (13); and alternative-care settings (six). Our findings suggest that inpatient infection-control practices should be extended to outpatient health care settings by assigning specific responsibility for infection control and by adapting surveillance methods and prevention measures. (<i>JAMA</i>. 1991;265:2377-2381)
THE ABSORPTION OF CALCIUM AND PHOSPHORUS
Journal: JAMA (1926)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Effects of Phthalic Acid Esters (PAEs) on the Neonate and Aspects of Teratogenic Actions
Authors: J. A. Thomas, D. B. Wienckowski, B. A. Gillies, M. J. Thomas, E. J. Youkilis
Journal: Environmental Health Perspectives (1986)

A review of the literature reveals that several different phthalic acid esters (PAEs) are capable of causing testicular damage.Phthalate-induced zinc deficiency is consistent with germinal epithelial damage.Among experimental animals, mice perhaps show the greatest sensitivity to phthalate-induced terata, but high doses/exposure are required.Little toxicologic information is available with regard to phthalate-induced effects upon the neonate.
Section 26.—Fibrositis
Journal: JAMA (1973)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Elevation of gamma delta T lymphocytes in peripheral blood and livers of patients with primary sclerosing cholangitis and other autoimmune liver diseases
Authors: E Martins
Journal: Hepatology (1996)

Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease that is possibly an autoimmune disease. Although gamma delta T cells represent a small proportion of the total T-cell population in healthy individuals, there is evidence to suggest a role for these cells in autoimmunity. Accordingly, the aim of this study was to investigate the population of gamma delta T cells in patients with PSC, compared with other chronic liver diseases. An elevation in the percentage and absolute numbers of gamma delta T cells was found in the peripheral blood of patients with PSC (8.66% and 0.13 x 10-6/L [P < .01 and < .05, respectively]) and autoimmune hepatitis (AIH) (8.03% and 0.13 x 10-6/L [both P < 0.001]) compared with controls (4.10% and 0.06 x 10-6/L). We also found an elevation in the percentage and absolute numbers of gamma delta T cells in the portal areas of patients with PSC (10.55% and 4.33 [P < .001 and < .001, respectively]), AIH (7.16% and 4.55 [P = .001 and < .001, respectively]), and primary biliary cirrhosis (PBC) (5.57% and 3.49 [P = .008 and < .001, respectively]) when compared with controls (2.23% and 0.81). These findings suggest a role for gamma delta T cells in the mechanism of immune damage in autoimmune liver diseases. (Hepatology 1996 May;23(5):988-93)
NUTRITION.
Authors: M. J. CROUCH
Journal: JAMA (1892)

I do not propose to present to you more than a suggestion of the merits of nutrition, and its relation to pathology. My studies along this line have forced me to conclusions which seem of vital importance to the science of medicine. It is true, our conclusions are more or less colored by the environments of the place from which we view the subject—so let us view the subject from analogous laws of nature. From the true scientific standpoint, in the organisms lie the principles of life, in the environments the conditions of life. The cart has been before the horse long enough —let us reverse the awkward position, and place them in a more practicable way. Instead of teaching that an<i>abnormal nutrition</i>is the<i>result</i>of "<i>disease,</i>," let us teach that "<i>disease</i>" is the result of abnormal nutrition. Then, and not till then, will we make progress toward
Hospice care in America
Authors: J. Rhymes
Journal: JAMA (1990)

Hospice care, an appropriate way of caring for many terminally ill patients, now is reimbursed by Medicare and other insurance systems. However, access to hospice care is limited by unavailability, ignorance, Medicare regulations, and internally imposed restrictions. Reasons for the barriers to hospice care and other appropriate terminal care are discussed, together with potential actions that might improve care for dying patients. (<i>JAMA</i>. 1990;264:369-372)
New challenges in the development of a conjugate pneumococcal vaccine
Authors: R. S. Baltimore
Journal: JAMA (1992)

Provision of data useful for the development of a conjugate pneumococcal vaccine is the subject of two studies published in this issue of<i>JAMA</i>. Both Eskola et al<sup>1</sup>and the Israeli Pediatric Bacteremia and Meningitis Group<sup>2</sup>looked at the epidemiology of pneumococcal infections in children to discover the extent of disease, prevalent serotypes, and definition of a high-risk target population of children as preliminary steps in devising a conjugate pneumococcal vaccine strategy. Why is the current vaccine, which has worked well in adults, not used for children, and why go to the trouble of developing a conjugate vaccine? It has been known for decades that the capsular polysaccharides of<i>Streptococcus pneumoniae</i>confer the antigenic specificity that defines different serotypes and that antibodies to these polysaccharides (also known as soluble-specific substances) are type-specific and protective for human beings. In 1945, MacLeod and associates<sup>3</sup>showed that these polysaccharides, used
Probing to bone in infected pedal ulcers
Authors: D. A. Nardone
Journal: JAMA (1995)

<h3>In Reply.</h3> —We thank Dr Nardone for his careful reading of our article and his thought-provoking comments. There are, as noted, limitations (practical and ethical) to the tests to which diabetic patients can be subjected in order to ascertain the presence or absence of pedal osteomyelitis. Nevertheless, in evaluating the probe test, the issue is not having a single criterion standard, but rather knowing the true state of the patients regarding osteomyelitis. A histologic diagnosis of osteomyelitis is definitive. Ruling out osteomyelitis by histology, unless one has a large bone sample (as was the case in 11 [seven early, four delayed] of our osteomyelitis-negative cases), is difficult because of the significant risk for sampling error. Prolonged follow-up without recurrence of an infected ulcer in the absence of therapy for osteomyelitis is as definitive as any other test to rule out osteomyelitis in this population. Additionally, we included other available information
Gentamicin and ticarcillin levels
Authors: L. K. Pickering
Journal: JAMA (1980)

<h3>To the Editor.—</h3> The article by Murillo et al (241:2401, 1979) entitled "Gentamicin and Ticarcillin Serum Levels" reported that mean concentrations of gentamicin sulfate and ticarcillin disodium in adult patients with neutropenia who received gentamicin plus ticarcillin were substantially lower than concentrations of gentamicin in patients receiving gentamicin plus cephalothin sodium or ticarcillin in patients receiving ticarcillin and cephalothin. Postulated mechanisms for these observations were differences in renal excretion between the groups and chemical interaction between ticarcillin and gentamicin with subsequent inactivation. The three groups described by Murillo et al differed with regard to age. The patients with low concentrations of ticarcillin and gentamicin in serum were younger (mean, 37.6 years) than patients in the groups receiving ticarcillin plus cephalothin (mean, 50.9 years) or cephalothin plus gentamicin (mean, 50.3 years). The glomerular filtration rate (GFR) as measured by inulin clearance is age related.<sup>1</sup>Representative values are listed in the
Camphorated Oil
Authors: Carmine Varano
Journal: JAMA (1979)

<h3>To the Editor.—</h3> Camphorated oil, the externally used, over-the-counter rubefacient and liniment, is an embarrassment to pharmacists, because they continue to stock and sell this questionably effective, toxic preparation, which has a history of being mistakenly ingested for castor oil, the laxative and cathartic.<sup>1-3</sup>It is also an embarrassment to the Food and Drug Administration because it has not as yet curbed use of this camphorcontaining product by mandating that manufacturers use a child-proof safety cap in addition to restricting the container packaging to a size not exceeding 30 mL and adding poison warnings in red ink on the label.<sup>4</sup> Now Kopelman et al (241:727, 1979) have published another case of camphorated oil's being mistakenly ingested, where 90 mL was inadvertently swallowed from a 120-mL bottle. The patient assumed that castor oil was being used. When does all this stop? Camphorated oil should be removed entirely from the
Distribution of hepatitis C virus genotypes in German patients with chronic hepatitis C: correlation with clinical and virological parameters Virchow-Klinikum Humboldt-University1, County Hospital Prenzlauer Berg2, Institute of Tropical Medicine3, Robert Koch-Institute4, Berlin, Germany
Journal: Hepatology (1995)

Nous rapportons un cas de spondylodiscite à Enterobacter cloacae, en rapport avec les pratiques à risque chez les usagers de drogues intraveineuses (IVDU).Il s’agissait d’un usager de drogues, ancien héroïnomane, sous traitement de substitution au long cours par la buprénorphine haut dosage avec un mésusage quotidien par voie intraveineuse de ce traitement depuis plusieurs mois. Cette infection a permis de découvrir la séropositivité du patient pour le VIH. L’évolution clinique a été remarquable par son caractère subaigu, l’apyrexie et un syndrome inflammatoire minime habituels chez les IVDU.Toute dorsolombalgie chez un patient IVDU, y compris dans le cas de la prescription régulière d’un traitement médical de substitution, et en particulier dans le cadre de l’infection par le VIH, doit faire évoquer une spondylodiscite en raison de la grande sensibilité aux infections de ces patients et des fréquentes bactériémies induites par la persistance ou la rechute transitoire de pratiques d’injection à risque (échange de matériel, réutilisation des aiguilles, des seringues, des cotons, risque manu-porté et/ou salivo-porté).We report a case of Enterobacter cloacae spondylodiscitis related to risk practices in intravenous drug addicts (IVDA).The patient, a former heroin addict, was receiving long-term, high-dose buprenorphine maintenance treatment. He had been misusing the treatment, injecting it daily for several months. The clinical course included several uncommon features that are usually found in IVDA patients: subacute infection, apyrexia, and minimal inflammatory syndrome. This infection also led to the discovery of his HIV infection.Any dorsolumbar pain in IVDA patients, including those receiving regular drug maintenance treatment and especially those with HIV infection, should suggest spondylodiscitis, because of these patients’ enhanced sensitivity to infection and the frequent bacteremia caused by persistent or transitory relapse involving injection (exchange of material, reuse of needles, syringes, cotton swabs, and risk of contamination through the hands or saliva).
Nation's first '21st-century' morgue opens with veteran chief medical examiner in charge
Journal: JAMA (1988)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Menstrual Disorders
Authors: Joseph Rogers
Journal: New England Journal of Medicine (1964)

IT should be emphasized that therapeutic efforts in menstrual disorders should not be instituted until a reasonable diagnosis has been made. Injudicious use of hormonal preparations too frequently leads to confusion regarding the underlying cause of the disorder. In many cases of menstrual abnormalities the difficult decision is not how to treat but if or when to treat. The problems discussed below are the amenorrheas, functional and dysfunctional uterine bleeding, dysmenorrhea and premenstrual tension.AmenorrheaUterine CausesRarely, one sees women who, after a curettage done in relation to some obstetric difficulty, fail to resume menstruation and do not respond . . .
Erratum
Authors: Lett Frs, A Africtous, Nessrs Allen, Londf Hanburys, ; Mir, G Ashton, Ieeds Birn, W Bell, Beverley Norwich, H Pb, W Bluck, Mr Brooks, J Ar Uff, ; Beattie, L Mr, London Bidwclt, Mel Co, Chirurgical Society, Bradford Mr, H Cowell, S Oekton-On-Tees Collinson, Mr Cartwright, W Coolivgridge, Mr Cholneley, ; Craig, L Cobh Ett, Stanisted Christv, B Collinis, Redcar Legh, Mr Demiietriadi, Huddersfield Discipnlnts, Mr Dobbs, Down- Ham Market, Mr Davies, Mr Davies, E Fa'r Play, Idr Foott, E Fothergill, Fiat Justitia, W Eemani, Altrincbam Garstang, E Groves, Clifton Mr, S Haynes, E Hall, Mr Hozier, N Heath, Mi Harmani, F Hewitt, Miss Johniso, ( Clifton, Ncweastle-On-Tyne Joynes, Philadelphia Keeo, L Kidd, C Lmg, F Low, L Marsdeii, ) Mackintosh, Lonldon Malaria, ; Mursell, Rtangoon Mello, B Member, C Mcclecw, Lonilon Mathisoni, C Millard, Mr Mautod, D 'a Eaterhamoi, Amsterdam Mtacgillavry, Mr Noble, Newcastle-On-Tyne Ogden, Oeci-Ori Onyx, F 0sbora, E Potter, L Parkes, B Poulton, K Pearson, ; Du' Liii
Journal: BMJ (1904)
Reply to Valeria Panebianco, Francesco Del Giudice, Yoshifumi Narumi, Giuseppe Simone, Ettore De Berardinis, and James Catto’s Letter to the Editor re: Helena Vila-Reyes, G. Joel De Castro, and James M. McKiernan’s Letter to the Editor re: Yunjin Bai, Yubo Yang, and Yin Tang’s Letter to the Editor re: Andrea Necchi, Marco Bandini, Giuseppina Calareso, et al. Multiparametric Magnetic Resonance Imaging as a Noninvasive Assessment of Tumor Response to Neoadjuvant Pembrolizumab in Muscle-invasive …
Authors: Helena Vila-Reyes, G. Joel DeCastro, James M. McKiernan
Journal: European Urology (2020)
Why Estimates of Physician Supply and Requirements Disagree-Reply
Authors: H. Gilbert Welch
Journal: JAMA (1993)

<h3>In Reply.</h3> —We appreciate the clarification given by Traxler et al on the methods used in the BHPr physician supply model. The discussion highlights the importance of specific assumptions in supply forecasts. As we discussed, and as Traxler et al emphasize, many of the discrepancies between forecasts are caused by differences in the assumptions about how various subgroups of physicians should be counted (ie, about how their workloads compare with the "average" physician's) and about how rates of entry to and exit from the profession will change with time. We apologize if we left the impression that BHPr makes no adjustment for physician attrition. Physician attrition may become one of the more volatile variables for future forecasts. Both Dr Kaufman and others have communicated to us their concern that the age of physician retirement is decreasing. Many would agree that the current practice environment has become more and more frustrating
Abstract 242: Bone-derived Stem Cells Repair The Heart After Myocardial Infarction Through Transdifferentiation And Paracrine Signaling Mechanisms
Authors: Jason M Duran, Catherine A Makarewich, Thomas E Sharp, Timothy Starosta, Fang Zhu, Nicholas E Hoffman, Yumi Chiba, Sharmeen Husain, Madesh Muniswamy, Remus M Berretta, Hajime Kubo, Steven R Houser
Journal: Circulation Research (2013)

Rationale: Autologous bone marrow- or cardiac-derived stem cell therapy for heart disease has demonstrated safety and efficacy in clinical trials but has only offered limited functional improvements. Finding the optimal stem cell type best suited for cardiac regeneration remains a key goal toward improving clinical outcomes. Objective: To determine the mechanism by which novel bone-derived stem cells support the injured heart. Methods and Results: Cortical bone stem cells (CBSCs) were isolated from EGFP+ transgenic mice and were shown to express c-kit and Sca-1 as well as 8 paracrine factors involved in cardioprotection, angiogenesis and stem cell function. Wild-type C57BL/6 mice underwent sham operation (n=21) or myocardial infarction (MI) with injection of CBSCs (n=57) or saline (n=59). Cardiac function was monitored using echocardiography with strain analysis. EGFP+ stem cells in vivo were shown to express only 2/8 factors tested (basic fibroblast growth factor and vascular endothelial growth factor) and this expression was associated with increased neovascularization of the infarct border zone. CBSC therapy improved survival, cardiac function, attenuated adverse remodeling, and decreased infarct size relative to saline-treated MI controls. By 6 weeks post-MI, EGFP+ cardiomyocytes, vascular smooth muscle cells and endothelial cells could be identified on histology. Isolated EGFP+ myocytes were smaller, more frequently mononucleated, and demonstrated fractional shortening and calcium currents indistinguishable from EGFP- myocytes from the same hearts. Conclusions: CBSCs improve survival, cardiac function, and attenuate remodeling by 1) secreting the proangiogenic factors bFGF and VEGF (stimulating endogenous neovascularization), and 2) differentiating into functional adult myocytes and vascular cells.
Correction: Genetic associations of T cell cancer immune response-related genes with T cell phenotypes and clinical outcomes of early-stage lung cancer
Authors: Sean J Judge, Morgan A Darrow, Steve W Thorpe, Alicia A Gingrich, Edmond F O'Donnell, Alyssa R Bellini, Ian R Sturgill, Logan V Vick, Kevin M Stoffel, Robert B Rebhun
Journal: Journal for ImmunoTherapy of Cancer (2020)