tbuckley/cabot-search huggingface dataset:
HOLLAND
Journal: JAMA (1923)

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Correction: Reduced SMAD7 Leads to Overactivation of TGF-β Signaling in MDS that Can Be Reversed by a Specific Inhibitor of TGF-β Receptor I Kinase
Journal: Cancer Research (2011)

In this article (Cancer Res 2011;71:955–63), which was published in the February 1, 2011 issue of Cancer Research (1), the name of the 17th author is incorrect. The correct name should be Ioannis Mantzaris.
Practicing Hope
Authors: Jennifer Lycette
Journal: JAMA Oncology (2016)

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Virology
Authors: Vernon Knight
Journal: JAMA (1995)

To this reviewer, as one who has observed viruses primarily as human pathogens, the monograph by Levy, Fraenkel-Conrat, and Owens is a stimulating and broadening experience. The authors attempt to cover all of virology, emphasizing that all living species have viruses associated with them. They point out that viruses can be classified into one of eight large groups, primarily based on whether they have DNA or RNA genomes coupled with their characteristics of replication. One thus sees a huge world of viral infections that show many common features despite the diversity of their hosts. The text also provides information on virus structure and replication, emphasizing biochemical properties. There is an excellent, large glossary of technical terms, which is very helpful to understanding the concise text. The book is essentially an annotated taxonomy of viruses, which is both challenging and intimidating. The similarities in structure and replication among viruses that affect
Deaths
Journal: JAMA (1972)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Changes of variabilities in the E2/NS1 region after interferon treatment and clinical outcome in chronic hepatitis type C Hepatology Section, Div. of Gastroenterology, International Medical Center of Japan
Journal: Hepatology (1995)

Two yellow fever vaccine strains 17D-204 and FNT (French neurotropic) or FNV were comparatively studied with their respective parents strains Asibi and FV (French viscerotropic). The latter showed a homology in their T1 oligonucleotides after genomic RNA fingerprinting (96.4%), which proved that, in 1927, the same type of virus was responsible for the outbreaks along the West African coast. Moreover, these strains showed high virulence in mice inoculated by peripheral routes. Many passages in different mammal hosts were made in order to attenuate the virulence of these strain. Despite some homologies observed in their genetic variations when compared to the wild strains, only the 17D-attenuated strain acquired different immunochemical and biological properties: its proteins E and NS1 showed modified structures by gel electroresis and by the neutralization test using a strain-specific anti-E monoclonal antibody, and this strain lacked virulence in mice after inoculation by peripheral routes.Nous avons réalisé l'étude comparative des souches de vaccin 17D-204 et FNV du virus amaril et de leurs souches parentales. L'homologie, dans les oligonucléotides T1, de l'ARN génomique des souches sauvages Asibi et FV et l'analogie des propriétés immunochimiques de leur protéine d'enveloppe E, déterminée par séroneutralisation, indiquents qu'en 1927 le même type de virus était responsable des épidémies côtières de l'Afrique de l'Ouest. Ces deux souches sont virulentes pour la souris inoculée par voies périphériques. Les modalités de passage sur des systèmes animaux en vue d'atténeur la virulence pour l'homme, ont été différentes pour chacune de ces deux souches. Malgré des analogies observées dans leurs variations génétiques par rapport aux souches de départ, ces deux souches vaccinales ont acquis des propriétés immunochimiques et biologiques différentes; seule la souche 17D montre des modifications de structures des protéines E et NS1 observées grâce à la méthode PAGE et par neutralisation à l'aide d'une type d'anticorps monoclonal anti-E; de plus, seule cette souche a perdu toute virulence pour la souris Swiss âgée de 8 jours infectée par voie périphérique.
Highlights
Journal: JAMA Surgery (2020)

Autofluorescent Parathyroid Gland Detection in Thyroidectomy 106Because damage to parathyroid glands can lead to postoperative hypocalcemia, their identification and preservation are pivotal during total thyroidectomy.In a randomized clinical trial, Benmiloud and colleagues assessed whether imaging systems using near-infrared autofluorescence light to identify parathyroid glands during surgery could improve parathyroid preservation and reduce postoperative hypocalcemia.They found increased rates of identification and preservation of the parathyroid glands and a lower rate of early postoperative hypocalcemia with the use of near-infrared autofluorescence.
Porro's Operation
Authors: C. Godson
Journal: BMJ (1891)

ated with tubal abortion allow of an easier explanation of abdominal and ovarian pregnancies.The ostium, as has already been noted, is very patulous in early tubal gestation.Let the process of extrusion be slow, and it is easy to conceive h1ow the membranes of the ovum may have time to acquire vascular adlhesions to neighbouring structures.'2The ovum, grow- ing larger, woul(d in time entirely disengage itself from tlle tube.In early tubal gestatioIl the tube does not always shiow a well-defined, abrupt, an(d spherical dilatation at the part where the footal sac lies.It is uniformly swollen, so that after the, escape of an early ovum it may soon collapse an(d leave no sign that a primiary gestationi lhas occurred.Hence the report "tubes iiormal " in an account of a case of allege(d primary ab(lominial gestation is no evidence that neither lhave lheld an earlv ovum.There is a strong, reason for us to agree with Zedel(ill believingthat early tubal abortion is not rare, being a frequent terminationi of extrauterine aestation and a coitinoni explanation of pelvic li-ematocele.
Medical News
Journal: JAMA (1977)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
DISCUSSION ON THE SEVERAL PAPERS ON TUBERCULOSIS.
Journal: JAMA (1897)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A HEALTH RECORD FOR 1932
Journal: JAMA (1933)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Attitudes of primary care physicians toward corporal punishment
Authors: K. F. McCormick
Journal: JAMA (1992)

<h3>Objective.</h3> —The purpose of this study was to determine whether or not family physicians and pediatricians support the use of corporal punishment. The frequency with which these physicians offer anticipatory guidance on discipline was also studied. <h3>Design.</h3> —Self-report survey, mailed to study participants. <h3>Participants.</h3> —The sample for this study was 800 family physicians and 400 pediatricians, randomly selected from the Ohio State Medical Board's roster of family physicians and pediatricians. Physicians with a subspecialty were excluded. Participants who did not return their surveys received a second, and if necessary, a third mailing of the survey. After three mailings, a total of 619 physicians (61%) completed a survey. <h3>Main Outcome Measure.</h3> —Participants were considered to support corporal punishment if they would tell a parent in their medical practice that spanking would be an appropriate response to any one of a series of childhood misbehaviors presented in the survey. <h3>Results.</h3> —Of family physicians, 70% (95% confidence interval [Cl], 66% to 75%) support use of corporal punishment. Of pediatricians, 59% (95% Cl, 52% to 66%) support corporal punishment. Of pediatricians, 90% (95% Cl, 86% to 94%) indicated that they include discipline issues either always or most of the time when providing anticipatory guidance to parents. Significantly fewer family physicians (52%; 95% Cl, 47% to 57%) indicated that they discuss discipline either always or most of the time when providing anticipatory guidance (<i>P</i>&lt;.01). <h3>Conclusions.</h3> —Most family physicians and pediatricians support the use of corporal punishment in spite of evidence that it is neither effective nor necessary, and can be harmful. Pediatricians offer anticipatory guidance on discipline more often than family physicians. (<i>JAMA</i>. 1992;267:3161-3165)
Reporting Negative Studies in the Mass Media
Authors: Elizabeth Neus
Journal: JAMA (1992)

<h3>To the Editor.</h3> —Koren and Klein<sup>1</sup>should have expanded their database search to include the month of September 1990 before deciding that reporters were biased against negative studies. If they had, they would have found numerous articles on the Jablon et al study,<sup>2</sup>the results of which were first announced at a major news conference in Washington, DC, on September 19, 1990. My employer ran that story on the front page; I was in Boston at the time and read a<i>Washington Post</i>version of the story on page 3 of the<i>Boston Globe</i>.<sup>3</sup> Later, when the Wing et al<sup>4</sup>study on leukemia in Oak Ridge, Tenn, workers appeared, it was also given front-page play in Cincinnati, Ohio.<sup>5</sup>That study received more attention than its companion piece that day because the Jablon et al study had already been covered extensively and was, frankly, old
Antibody Improves Survival in Gastric Cancer
Journal: Cancer Discovery (2016)

Results from a randomized phase II study indicate that adding the experimental antibody IMAB362, which targets the tight junction protein claudin18.2, to standard chemotherapy is more effective than chemotherapy alone in previously untreated patients with advanced gastric cancer. IMAB362 extended progression-free and overall survival by 3.1 months and 4.8 months, respectively.
On Some of the Principal Events in the Clinical History of Asthma
Authors: H. Salter
Journal: BMJ (1859)

II.-TENDENCY TO HABITU'DE: ILLUSTRATIVE CASES.ALI those who are familiar with asthma, must have observed in it a disposition to habitude-a disposition to maintain and constantly repeat any peculiarity it may have acquired.And this is probably due to the very same tendency of the affection that makes it periodic, to the tendency to repetition, to its
index to advertisers
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Workmen's Compensation and the Physician: A Manual for the Use of General Practitioners and Insurance Carriers
Journal: JAMA (1942)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Books Received
Authors: M. THERESE SOUTHGATE
Journal: JAMA (1985)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
HIV-specific T-helper activity in seronegative health care workers exposed to contaminated blood
Authors: M. Clerici
Journal: JAMA (1994)

<h3>Objective.</h3> —To evaluate human immunodeficiency virus (HIV) type 1—specific cellular immune responses in HIV-seronegative health care workers with occupational high-risk exposures to HIV-infected (HIV-positive) patients. <h3>Design.</h3> —Peripheral blood mononuclear cells (PBMCs) were obtained after occupational exposures to HIV, and PBMCs from health care workers exposed to HIV-negative patients served as controls. The PBMCs were stimulated in vitro with HIV envelope synthetic peptides. Interleukin 2 (IL-2) production was measured in a bioassay. The HIV antibody status was determined by standard enzyme-linked immunosorbent assays. Exposed individuals were also evaluated for HIV proviral DNA by polymerase chain reaction techniques. <h3>Participants.</h3> —The PBMCs from eight health care workers with high-risk exposures and nine control health care workers were studied. <h3>Results.</h3> —The PBMCs from all individuals showed strong IL-2 production to control antigens, indicating intact T-helper function. Interleukin 2 production to HIV peptides was detected in PBMCs from six of eight HIV-exposed individuals, but in only one of the nine health care workers exposed to HIV-negative body fluids (<i>P</i>&lt;.008). None of the HIV-exposed health care workers became infected as determined by negative HIV antibody and polymerase chain reaction analysis after follow-up evaluation that ranged from 8 to 64 weeks. <h3>Conclusion.</h3> —Human immunodeficiency virus—specific T-helper activity was detected in six (75%) of eight HIV-negative health care workers with exposure to HIV-positive body fluids. Potent HIV-specific T-helper activity was detectable 4 to 8 weeks after the exposure and was lost in individuals followed up for 8 to 64 weeks. Three health care workers remained responsive at 8,19, and 24 weeks. Exposure to HIV without evidence of subsequent infection appears to result in activation of cellular immunity without activation of antibody production. (<i>JAMA</i>. 1994;271:42-46)