tbuckley/cabot-search huggingface dataset:
Incorrect Reference Citation
Authors: Rebecca Gooch, Jeremy Kahn
Journal: JAMA (2014)

In Reply We did not argue that ICU admission directly harms patients with low illness severity.Our Viewpoint acknowledged a small potential benefit of close observation in the ICU for these patients.Therefore, we did not use the term supplierinduced demand, which, as Mr Friedman correctly notes, implies but does not require a lack of marginal benefit. 1 Instead, we argued that this small potential benefit does not justify the high costs of building and maintaining ICUs.The idea that excess ICU bed supply leads to overuse is well supported by data, both old 2 and new. 3 Friedman's suggestion that current use patterns represent an efficient use of resources lacks the same evidentiary support.Moreover, although it is true that ICU beds carry high fixed costs, and therefore the costs to individual patients are low, we did not propose simply not admitting low-risk patients.We proposed closing ICU beds and thus, substantially lowering fixed costs.Friedman's alternative solution of varying ICU prices based on appropriateness is intriguing but impractical.It would require accurate and reliable assessment of ICU appropriateness, which is currently impossible 4 ; and it would lead to explicit rationing by ability to pay, which is ethically untenable. 5 Our solution is to trust the innate ability of physicians to perform safe implicit rationing in the setting of constrained supply, 6 maintaining quality while reducing the costs of care.
Scleroderma
Authors: Armando Gabrielli, Enrico V. Avvedimento, Thomas Krieg
Journal: New England Journal of Medicine (2009)

This account of the mechanisms of scleroderma highlights the genetic and molecular changes that cause the vascular changes and fibrosis in the disease. The role of autoantibodies, of which there are several in scleroderma, is unclear. The authors outline a stepwise process that begins with inflammation, reaches its zenith in fibrosis, and ends in atrophy.
HEREDITARY NEPHROPATHY, DEAFNESS, AND RENAL FOAM CELLS
Journal: JAMA (1962)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Analysis of the Patient-Therapist Relationship in Dynamic Psychotherapy: An Experimental Study of Transference Interpretations
Authors: Per Høglend
Journal: American Journal of Psychiatry (2006)

Objective: The purpose of this study was to measure the effects of transference interpretations (the assumed core active ingredient) in dynamic psychotherapy, using an experimental design. Method: One hundred patients were randomly assigned to two groups. One group received dynamic psychotherapy over 1 year, with a moderate level of transference interpretations, while the other group received dynamic psychotherapy with no transference interpretations. The most common axis I disorders were depression and anxiety disorders. Forty-six patients fulfilled the general criteria for personality disorder. Seven experienced psychotherapists treated patients in both groups. Five full sessions from each treatment were rated by two evaluators with process measures in order to document treatment integrity. Outcome variables were the Psychodynamic Functioning Scales, Inventory of Interpersonal Problems Scale-Circumplex version, Global Assessment of Functioning Scale, and Symptom Checklist-90-R. Quality of Object Relations Scale (lifelong pattern) and personality disorders were preselected as possible moderators of treatment effects. Change was assessed using linear-mixed models. Clinically significant change was also calculated. Results: The authors could not demonstrate differential treatment effects between the groups. However, the moderator analyses showed that transference interpretations were more helpful for patients with a lifelong history of less mature object relations. Small negative effects were observed for patients with mature object relations. Conclusions: The authors could not show differences in average effectiveness between treatments. However, the moderator analyses indicated that treatment worked through different active ingredients for different patients. Contrary to common expectation, patients with poor object relations profited more from therapy with transference interpretations than from therapy with no transference interpretations.
In vivo evidence of enhanced guanylyl cyclase activation during the hyperdynamic circulation of acute liver failure
Authors: F Schneider
Journal: Hepatology (1994)

Nitric oxide and atrial natriuretic peptides are the main activators of guanylyl cyclases, which transform ITP into cyclic GMP and thereby contribute to the decrease of vascular tone. To investigate the increase, if any, of plasma cyclic GMP concentrations in human patients with hyperdynamic circulation resulting from acute liver failure and to ascertain whether guanylyl cyclase activation is involved in the decline of systemic vascular resistance that occurs in this pathophysiological condition, we simultaneously recorded hemodynamic data and cyclic GMP levels in patients with fulminant liver failure before and after liver transplantation and in normokinetic patients undergoing abdominal nonseptic surgery. We also compared these data with those recorded in patients with hyperkinetic shock resulting from gram-negative sepsis or nitric oxide-independent vasomotor agent (carbamate) overdose. In all these patients we simultaneously studied kidney function, platelet counts and atrial natriuretic peptides. Patients with fulminant liver failure had higher cyclic GMP concentrations than did control patients undergoing abdominal surgery (11.02 ± 1.55 pmol·ml−1 vs. 1.77 ± 0.18 pmol · ml−1, P < 0.001). At similar heart-loading conditions these concentrations were lower than those in gram-negative septic shock (18.2 ± 1.35 pmol·ml−1, p < 0.05) but higher than those in carbamate-induced shock (3.6 ± 0.7 pmol·ml−1, p < 0.01). In addition, cyclic GMP concentrations significantly decreased from the fulminant liver failure period to the posttransplantation period, although atrial natriuretic peptide levels did not change significantly and kidney function worsened. During the period of fulminant liver failure, cyclic GMP levels correlated with the decline in peripheral resistance but not with other hemodynamic or biological data. With the improvement of peripheral resistance after the transplantation procedure, they did not further correlate with systemic vascular resistance, only with creatininemia. Together these results suggest that guanylyl cyclase activation is involved in the low vascular resistance observed during acute hepatocellular syndrome; furthermore, they indicate that particulate guanylyl cyclase activation only partially explains the increase in cyclic GMP observed during fulminant liver failure and put forward a role for soluble guanylyl cyclase activators such as nitric oxide. (Hepatology 1994;19;38–44).
Diagnostic Value of Isolated Urinary Mucopolysaccharides and Lymphocyte Inclusions in Gargoylism
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Reply
Authors: S. Javaheri, R. M Smith, D. Wiltse
Journal: Thorax (1988)

Measurement of effective pulmonary blood flow by soluble gas uptake SntI,-I was interested to read the article by Dr RJ Pierce and others (August 1987;42:604-14).In their description of the methods the authors perpetuate a few misconceptions which commonly appear in papers about the inert gas method of estimating pulmonary blood flow.
Residency Overwork
Authors: Allan Tachauer
Journal: Annals of Internal Medicine (1996)

Letters15 May 1996Residency OverworkAllan Tachauer, MDAllan Tachauer, MDRavenswood Hospital Medical Center; Chicago, IL 60640Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-124-10-199605150-00037 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Dr. Green [1] brings a unique and refreshing perspective to a prevalent problem in residency training. There is no argument that long hours and fatigue probably do not promote high ethical standards. What Dr. Green only briefly mentions and what the accompanying editorial [2] does not address is probably as important as fatigue. As a teacher still able to remember his not-so-remote residency, I believe that the more formidable challenge to the virtuous resident is the paucity of role models. We learn by example, and both the good and the bad are equally powerful. A tired resident ...References1. Green MJ. What (if anything) is wrong with residency overwork? Ann Intern Med. 1995; 123:512-7. Google Scholar2. Griner PF. Residency overwork and changing paradigms of service [Editorial]. Ann Intern Med. 1995; 123:547-8. Google Scholar Author, Article, and Disclosure InformationAuthors: Allan Tachauer, MDAffiliations: Ravenswood Hospital Medical Center; Chicago, IL 60640 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byMinimizing excessive resident hours in surgical training programs 15 May 1996Volume 124, Issue 10Page: 933KeywordsFatigueGraduate medical educationResidency ePublished: 15 August 2000 Issue Published: 15 May 1996 Copyright & PermissionsCopyright © 1996 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Patient protection in cancer chemotherapy
Authors: S. A. Schwartz
Journal: JAMA (1966)

Eight patients undergoing intensive cancer chemotherapy have been treated in a protection unit. The antibiotic protocol in this program was designed to prevent the appearance of resistant organisms. The preliminary results indicate that it is quite feasible and practical to maintain an individual in a relatively germ-free environment for long periods of time. In this small group of patients there was no evidence of infection with the more common pathogens, despite severe bone marrow depression and leukopenia induced by antitumor agents.
Alterations in serum enzymes in chronic renal failure
Authors: G. L. Bailey
Journal: JAMA (1970)

Serum lactic dehydrogenase (LDH), glutamic oxaloacetic transaminase (GOT), and amylase levels were determined in 76 chronically uremic patients. Serum LDH was increased in 77% of 486 determinations, and only 10% of the abnormal levels could be accounted for by pathological conditions known to increase LDH. Serum GOT levels were generally normal. Serum amylase was increased in 32% of 175 determinations. There is a high incidence of abnormal LDH and amylase levels in uremic patients. We caution against overinterpretation of these findings and the costly and often unnecessary search for their significance.
Angiology, Baltimore
Journal: JAMA (1967)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Repeated coronary artery spasm in a young woman with the eosinophilia-myalgia syndrome
Authors: P. A. Hertzman
Journal: JAMA (1992)

We report a case of repeated coronary artery spasm with myocardial injury in a 37-year-old woman with the eosinophilia-myalgia syndrome. This patient did not have a medical history of cardiac-related illness or risk factors for coronary artery disease. The presence of eosinophil granule major basic protein in otherwise normal-appearing myocardial tissue, along with normal plasma levels of tryptophan metabolites, suggests that the mechanism of vasospasm in this patient might involve toxic eosinophil proteins or focal myocardial lesions, but not the production of excess tryptophan metabolites. (<i>JAMA</i>. 1992;267:2932-2934)
Effect of LSD on human pregnancy
Authors: W. H. McGlothlin
Journal: JAMA (1970)

The frequencies of spontaneous abortions, premature births, and birth defects in 121 human pregnancies following relatively infrequent, low doses of medically administered lysergic acid diethylamide are within the normal ranges. The incidence of spontaneous abortions was above average for a small sample of 27 pregnancies where LSD was ingested under both medical and nonmedical conditions. Spontaneous abortions occurred significantly more frequently when the mother received LSD as opposed to the father only; however, the data do not permit the establishment of a clear causal relationship.
The Etiology of Enteric Fever
Authors: A. Collie
Journal: BMJ (1885)

THE BRPTIhH MEDICAiL JOURNAL.(Apri1 26 if a battalion had five companies, so the Swiss field-hospital has five "sections," each called "ambulances," or, as we would call them, " field-hospitals."Each section has four medical officers, one quarter.master, one apothecary, and thirty-four non-commissioned officers and men of tho medical corps.This is a very neat unit ; but as it is intended only for European warfare, it is not an accurate guide for us, who can find no assistance whatever in a New Zealand fern-thicket, on the plains of Egypt, on the Crimean steppes, or in the jUDngeS of Asbantec.We must embark with the niieaiis of being efficient, or we shall never be efficient at all.i.The Colboan of Sick Tramnport Car?iagcs.-Sofar as I under- stand it, there are no definite units, calledI"bearer-companies," in the Swiss service.They separate all the sick transport-wagonis into units by themselves, and call them " transport-columns," assigninig to each two medical officers and( ten rank and file, andl thirty-two wagons.These act as convoys; antl by adding a coluiumn of carriages to the pcrsontncl of an ambulance (field-lhospital) a bearer-comipany is made pro temlpore.
Incorrect Laboratory Value in Table
Journal: JAMA (1982)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
In Reply
Authors: Marta Cuadros, Emiliano Honrado, Magdalena Zajac, Javier Benitez, Beatriz Martinez-Delgado, Sandeep S. Dave, Louis M. Staudt, Elaine S. Jaffe, Roger Milne, Javier Alves, Jose Rodríguez
Journal: Journal of Clinical Oncology (2007)
THE CORRESPONDENCE DIPLOMA MILL.
Journal: JAMA (1902)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
BI-01 * BLOOD SERUM AND C.S.F. ANALYTES SHOW POTENTIAL FOR USE AS A DIAGNOSTIC BIOMARKER FOR LOW AND HIGH GRADE GLIOMA
Authors: P. Abel
Journal: Neuro-Oncology (2014)

INTRODUCTION: There is a need for a biomarker with high sensitivity and specificity to aid glioma diagnosis. Current methods of diagnosis are invasive with the diagnostic test requiring hospitalisation. A rapid diagnostic based upon blood serum and CSF samples would allow for a relatively non-invasive test and open up the possibility of screening for glioma as well as effective treatment monotoring and prediction of tumour recurrance. Analysis of the source of the proteins may reveal information regarding the mechanism of immunosuppression in these tumours. MATERIALS AND METHODS: Serum from 110 high grade and 44 low grade glioma patients, were analysed along with 33 control sera from non-cancerous patients. CSF was also analysed from 8 high grade glioma patients taken with lumbar puncture. The analysis was performed using a luminex immunoassay measuring 36 cancer-associated analytes simultaneously. Immunohistochemistry was also performed on tumour tissue from the same patients. RESULTS: There were significant differences in several analytes between sera and CSF of glioma patients of low and high grade and non-cancerous control patients. These were Angiopoietin, Follistatin, FGF, G-CSF, sHER2neu, HGF, sIL-6R, Leptin, PDGF-BB, PECAM-1, Prolactin and sVEGFR-1. CSF level differences confirmed and correlated with serum level differences in the majority of cases. Tumour tissue also revealed increased expression of several of the proteins. CONCLUSIONS: These results suggest that specific protein levels in different media can be used to detect and confirm a glioma diagnosis as well as to distinguish between low and high grade gliomas. These results may also be used to predict tumour recurrance and transformation between low and high grade gliomas. There was an interesting up-regulation of several receptor analytes that may have masked the presence of their associated ligand indicating that some potential biomarkers may be obscured. Modification of the capture antibody could reveal more potential biomarkers with greater clinical usefulness.
SIGNIFICANCE OF ETIOLOGIC FACTORS IN THE TREATMENT OF PEPTIC ULCER
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Long term treatment of chronic hepatitis D with lymphoblastoid interferon: 10 MU vs 5 MU, an interim report of a randomized controlled trial . Departrment of Gastroenterology, Molinette Hospital, Torino; *Institute of Internal Medicine, Cerevello Hospital, Palermo; ?Division of Gastroenterology; Casa sollievo della Sofferenza, San Giovanni Rotondo; ?Division of Gastroenterology, San Orsola Hospital, Bologna; oDepartment of Internal Medicine II, Modena, Italy
Journal: Hepatology (1995)