tbuckley/cabot-search huggingface dataset:
Analysis of Foreign Journals: Journal des Connaissances, &amp;c. Feb. 1841. No. 8
Journal: BMJ (1841)

Abdomen tender, and puffy about the margin of the wound.Gut extremely dark in colour.10 P.M. Gut in a state of gangrene.The ligature re- moved from the upper margin of the wound, in order to rlnove any strangulation of the intestine which might be caused by it.Abdomen more tender, pulse very rapid, features pinched up-breathing exceedingly quick, short, and faint-unsteadiness about his movements, similar to that of delirium tremens-picks the bedclothes-constantly wandering.He is evidently sinlking.In the course of the day he confessed, that during the night of Sunday, in a fit of passionate remorse at the course of life he had been latly pursuing, he made an attempt to cut his throat with an ordinary clasp-knife.Failing, however, from the bluntness of the instrument, he violently plunged it into his abdomen.The knife was af- terwards found hidden in the bedclothes.March 3d, 7 A.M. Mortuus estL From the time of the infliction of the injury to bis death he had no sickness, and appeared to suffer scarcely any pain.Examination madejive hours after death.The body was rigid.A vertical wound was seen in the mesian line at the umbilici%, three inches in length, and extending tbrough the whole tbickness of the abdominal wall.The margins were dark and fetid.The two ends of the colon, which were hanging outside the opening, were black, easily broken down, ratler dry, and continued to the extent of several inches within the abdomen dark and gangrenous, or in a state nearly .approachingit.The bowels generallyr were not much distended.There was uni- versal peritonitis, flakes of lymph every where gluing the viscera together.The adhesive matter was easily torn through, and indeed but little removed from puriform de- posit in its character.The omentum was congested, con- tracted, dark in colour, and easily lacerable.Extensive pleuritis was found on both sides of the chest.There was a linear graze in-the skin across the throat, the presence of which was accounted for by the man's confession.In the above case, will the circumstance of the large bowel only being involved in the injury, account for the absence of vomiting, the slight prostration exhibited, and the general mildness of the symptoms?*
THE PULSE RATE IN RELATION TO METABOLISM AND DIAGNOSIS
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Second Colorectal Cancer in Patients Who Had First Colon Cancer Treated with Surgery and Chemotherapy
Journal: Annals of Internal Medicine (2002)

Summaries for Patients19 February 2002Second Colorectal Cancer in Patients Who Had First Colon Cancer Treated with Surgery and ChemotherapySearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-136-4-200202190-00001 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail What is the problem and what is known about it so far?Colorectal cancer is cancer of the colon (large intestine) or rectum. Second colorectal cancer can occur in patients after treatment for first colon cancer. For this reason, patients typically have surveillance with periodic colonoscopy after treatment for colon cancer. Colonoscopy involves looking into the rectum and colon through a tube-shaped instrument for precancerous abnormalities or tumors. Current recommendations suggest that patients should have colonoscopy 1 year after treatment; then, if the results of the first colonoscopy are normal, they should have colonoscopy every 3 to 5 years. However, ... Author, Article, and Disclosure InformationAffiliations: The summary below is from the full report titled “Surveillance for Second Primary Colorectal Cancer after Adjuvant Chemotherapy: An Analysis of Intergroup 0089.” It is in the 19 February 2002 issue of Annals of Internal Medicine (volume 136, pages 261-269). The authors are RJ Green, JP Metlay, K Propert, PJ Catalano, JS Macdonald, RJ Mayer, and DG Haller.Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. The summaries may be reproduced for not-for-profit educational purposes only. Any other uses must be approved by the American College of Physicians-American Society of Internal Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoSurveillance for Second Primary Colorectal Cancer after Adjuvant Chemotherapy: An Analysis of Intergroup 0089 Robert J. Green , Joshua P. Metlay , Kathleen Propert , Paul J. Catalano , John S. Macdonald , Robert J. Mayer , and Daniel G. Haller Metrics 19 February 2002Volume 136, Issue 4Page: I-29KeywordsCancer treatmentChemotherapyColonoscopyColorectal cancerDeath ratesLarge intestineLymph nodesPatientsRectumSurgery ePublished: 19 February 2002 Issue Published: 19 February 2002 CopyrightCopyright © 2002 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...
Role Models
Authors: Bruce D. Weinstein
Journal: JAMA (1995)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Malar Rash
Authors: Sarah E. Goglin, Mary E. Margaretten
Journal: New England Journal of Medicine (2021)

A 34-year-old woman presented with a rash on both cheeks that spared the nasolabial folds and with joint pain in her hands and knees. Laboratory studies showed leukopenia and positive anti-Smith and anti-RNP antibodies, and a diagnosis of systemic lupus erythematosus was made.
The Normal IGHV1-69-derived B Cell Repertoire Contains “Stereotypic” Patterns Characteristic of Unmutated CLL.
Authors: Francesco Forconi, Kathleen N Potter, Isla Wheatley, Nikos Darzentas, Elisa Sozzi, Francesco Lauria, Kostas Stamatopoulos, Christopher Ian Mockridge, Graham Packham, Freda K Stevenson
Journal: Blood (2009)
Remission in Systemic Lupus Erythematosus After Combination Chemotherapy for Hodgkin's Disease
Authors: James S. Goodwin
Journal: JAMA (1980)

IT IS generally agreed that the prognosis for patients with systemic lupus erythematosus (SLE) improves dramatically after the introduction of high-dose corticosteroids.<sup>1,2</sup>Evidence of benefit from treatment with cytotoxic agents is less compelling, but many authorities recommend them for patients with diffuse proliferative glomerulonephritis or cerebritis.<sup>2</sup>Lack of positive proof of their efficacy is due to difficulty in obtaining the large number of patients required for a thorough study (ie, one that avoids the type II error of finding no difference between treatment groups, even though one exists). In the absence of such studies, individual judgments are based more on clinical experience and anecdotal reports. The present report describes a man with SLE who experienced a prolonged, complete, clinical and serological remission from the disease after combination chemotherapy for coincidental Hodgkin's disease. This case is presented to raise the question of whether effective combination chemotherapy might be safer
OBSERVATIONS ON THE SMALL INTESTINE
Journal: JAMA (1933)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Heberden Round
Journal: Annals of the Rheumatic Diseases (1951)

PRESIDENTIAL ADDRESS in circumstances where stress and strain may be met with on recovery or where compensation for injury is hopefully, if subconsciously, anticipated.The pains of anxiety states may well be due, in part, to muscle contraction and spasm-the somatic expression of the increased nervous tension which is occa- sioned by fear.Too often a depressive psychosis is overlooked as a cause of per- sistent psychogenic pain, though few would fail to appreciate the origin of the bizarre pains described with unrestrained verbal embellishments by the paranoidal valetudinarian and hypochondriac.I have sought to show that the problems presented by the clinical analysis of pain can be solved only by those who look at the " whole " man.Those whose major field of medical practice is rheumatology must beware of the compartmental outlook, for their diagnostic field is general medicine.They must adopt the " synoptic " view and decide, if pain be the presenting symptom, whether it is dominantly physical or psychogenic.They must be prepared to spend time on taking the history and making a full examination, so that they can determine what accessory procedures, provided by x rays and clinical pathology, are necessary to reach a complete diagnosis, but they must not be bemused by the minor devi- ations from the normal which may be revealed by diagnostic machines, but which cannot possibly be related to the patient's complaints.I do not claim to have presented any novel thesis; nor, indeed, were I able to do so, would this occasion have been appropriate.I have sought to review the more recent advances in our knowledge of pain and the help they give to its clinical interpretation, so that yet another step may be taken towards fulfilling Hilton's belief that " every pain has its distinct and pregnant signification if we will carefully search for it ".Case 1, Mrs. E.B., aged 32, pregnant.-Shepresented the typical clinical features of Addison's disease including pigmentation of the skin in the accepted situations.This was her second pregnancy, and the disease appeared to have followed immediately after the first pregnancy.She was treated with DOCA and salt.She was then put on to cortisone and at the time of the meeting was taking 15 mg.daily with DOCA twice 227
Gastrointestinal Bleeding
Authors: Emmanuel Weiss, Catherine Paugam-Burtz
Journal: Endoscopy (2003)

A trend toward a lower relative frequency of peptic ulcer disease (PUD) as the cause of upper gastrointestinal bleeding has been observed in recent years. A multicenter study in the United States confirmed this tendency, comparing data from the last 3 years with historical controls from the years 1983 - 1992. The frequency of PUD decreased significantly from 59 % to 38 %. Effective antisecretory drugs, Helicobacter pylori eradication treatment, and newer nonsteroidal anti-inflammatory drugs (NSAIDs) are all probably responsible for this decline. The frequency of variceal bleeding increased to a lesser extent, but also significantly, from 12 % to 16 %. Probably the most striking finding was an increase in the frequency of erosive esophagitis, from 4.3 % to 12.9 %; the authors were not able to explain this increase. The frequencies of other causes remained at a similar level to that seen before, except for gastric/duodenal erosions (with a decline from 4.4 % to 1.7 %) and Dieulafoy's lesions (with an increase from 0.6 % to 2.3 %); however, these changes were not significant. A significant improvement in almost all outcome measures (rebleeding, surgery, and death rates) in all groups of patients (PUD, varices, others) was observed in the recent period in comparison with the decade 1983-1992 [1].
The second Baby Doe rule
Authors: L. M. Kopelman
Journal: JAMA (1988)

<h3>In Reply.</h3> —In her Letter, Dr Kopelman accurately points out that while the Supreme Court has struck down the BDR-I, the BDR-II, which is based on the 1984 amendments to the Child Abuse Prevention and Treatment Act, remains in effect. This rule forbids the "withholding of medically indicated services." Exceptions to this rule are to be made only when "(1) the infant is chronically and irreversibly comatose; (2) the provision of such treatment would merely prolong dying or not be effective in ameliorating or correcting all the infant's life-threatening conditions or otherwise be futile in terms of the survival of the infant; or (3) the provision of such treatment would be virtually futile in terms of the survival of the infant and the treatment itself under such circumstances would be inhumane." The notion that these few directives are in some way capable of providing meaningful guidance in the vast array
Shaul Tchernichovsky
Authors: Meir Yoeli
Journal: New England Journal of Medicine (1965)

IN the renaissance of the Hebrew language and its literature two great poets truly stand out: Chaim Nachman Bialik and Dr. Shaul Tchernichovsky.One sees them through the mist of time and at the turn of the century, standing guard, shielding and reviving their people's martyred soul. The first holds a flaming torch and a vessel full of tears, and the other sunrays and flowers of the field. Bialik is Israel's national poet; the noble poetry of Shaul Tchernichovsky belongs to the world at large.Shaul Tchernichovsky was born on August 20, 1875, in the little village of Michailovka (district . . .
The Medical News Visiting List for 1896.
Journal: JAMA (1895)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Immunoblastic Lymphadenopathy
Authors: Frank J. Glassy
Journal: JAMA (1977)

<h3>To the Editor.—</h3> Most of the comments concerning immunoblastic lymphadenopathy (236:2098, 1976) are quite appropriate. However, I would like to emphasize the original authorship of this entity. It is stated that Frizzera et al<sup>1</sup>are the "first authors to give sufficient emphasis to the importance" of this disorder. The article by Lukes and Tindle<sup>2</sup>followed six months after that by Fizzera et al, who note in their introduction that this lesion was described by Lukes at a workshop on classification of non-Hodgkin's lymphomas held from June 25 to June 29, 1973. Lukes and Tindle were the first to describe immunoblastic lymphadenopathy at this and similar meetings<sup>3</sup>after they recognized that this lesion was a histopathologic entity that must be distinguished from malignant lymphomas and Hodgkin's disease. Therefore, they should be given proper recognition, as Frizzera and coworkers do in their second reference. Furthermore, Lukes' larger series was collected over
THURSDAY 24TH MARCH
Journal: Gut (1994)

Aims High dietary ascorbic acid (AA) reduces gastric cancer risk, and may act in gastric juice by reducing N-nitroso compound formation or in mucosa by scavenging free radicals.We investigated whether oral AA supplementation increases mucosalband juice levels, and if this is modified by gastritis (a cancer risk factor).Methods Subjects were recruited from patients undergoing endoscopy for dyspepsia. 34patients were supplemented with AA 500 mg b.d. for 14 days prior to endoscopy, ceasing supplementation on the day before endoscopy.49 patients were not supplemented.At endoscopy samples of blood and gastric juice were taken.Mucosal biopsies were also obtained from patients as detailed below.AA levels were measured in all specimens, and the biopsies examined histologically.Results 37/49 unsupplemented patients and 20/34 supplemented patients had gastritis.Antral and body biopsies were obtained from all unsupplemented patients, and from 26 of the supplemented group. 6unsupplemented and 26 supplemented patie-nts had oesophageal and duodenal (1st [Dl] and 2nd [D2] parts) biopsies taken.Median AA concentrations (pmol/Kg) were: _ mplasma juice oesoph body antrum| Dl |D2
The Two-Armed Bandit
Journal: JAMA (1973)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Tuberculosis screening of applicants for US immigration
Authors: J. Bayuk
Journal: JAMA (1995)

<h3>To the Editor.</h3> —The review of tuberculosis (TB) surveillance data by Dr Cantwell and colleagues<sup>1</sup>highlights non—US-born individuals as the source of 60% of the total increase in TB cases in the United States and acknowledges specific concerns about overseas diagnosis of TB and follow-up after immigration to the United States. The large potential contribution of active TB cases by migrants is demonstrated by data retrieved from the Immigration Examination Clinic in Manila, Philippines, and a brief summary of current screening procedures. One purpose for the immigration medical examination is to exclude applicants with infectious TB.<sup>2</sup>This is determined by an abnormal chest roentgenogram (CXR) and whether or not the sputum smear is positive or negative for tubercle bacilli. An applicant with a stable, abnormal CXR and negative sputum smears is eligible to migrate to the United States. An applicant with an abnormal CXR or series suggestive of active
A Shocking Turn of Events
Authors: Ersilia M. DeFilippis, Anand Vaidya, David Braun, Neal Lakdawala, Piotr Sobieszczyk
Journal: New England Journal of Medicine (2018)

A 38-year-old woman presented to her primary care physician in 2010 for evaluation of an upper respiratory infection and shortness of breath. The patient reported having a cough . . .
Highlights
Journal: JAMA Oncology (2018)

ERBB gene mutations may affect the efficacy of therapies targeting the ERBB signaling pathway.Goss et al evaluated the association between the ERBB family of mutations and outcomes in afatinib-or erlotinib-treated patients with lung squamous cell carcinoma using samples from the LUX-Lung 8 trial.Of 245 evaluable patients, 53 had tumors with at least 1 ERBB mutation.Among afatinib-treated patients, progression-free and overall survival were longer in those with ERBB mutation-positive disease-in particular HER2 mutations-than in those without.HER2 mutations may be a biomarker for prioritizing afatinib treatment in this population.Gandara et al provide an Invited Commentary.