tbuckley/cabot-search huggingface dataset:
The Role of Biomarkers in Reproductive and Developmental Toxicology
Authors: Thomas W. Clarkson
Journal: Environmental Health Perspectives (1987)

A massive outbreak of methylmercury poisoning took place in the winter of 1971-1972 due to the consumption of homemade bread contaminated with a methylmercury fungicide. The longitudinal analysis of the mother's head hair, collected after delivery of the baby, provided a means of recapitulating exposure to methylmercury during pregnancy. Methylmercury is incorporated into newly formed hair at a concentration that is proportional to the simultaneous concentration in blood. Since hair grows at a rate of approximately 1 cm/month, longitudinal analysis of the hair strand, centimeter by centimeter, will give a month by month recapitulation of blood levels. Depending on the length of the hair strand, it is possible to recapitulate several years of exposure. Using longitudinal hair analysis, it was possible to compare the methylmercury levels in the mother during pregnancy with the severity and frequency of effects in her offspring. As in the previous incidents, high levels of prenatal exposure led to severe brain damage. However, it was also possible to identify milder effects of methylmercury as manifested by delayed development. It was possible to demonstrate a dose-effect and dose-response relationship between the maximum concentration of methylmercury in maternal hair during pregnancy and evidence of delayed development and mild neurological abnormalities in the offspring. These relationships provided quantitative evidence that the developing nervous system is more susceptible to damage than the mature brain.
THE AMOUNT OF OPIATES USED IN THE LEGITIMATE PRACTICE OF MEDICINE
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
MISCELLANY.
Journal: JAMA (1890)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Letter: Dangers of oxytocin-induced labour to fetuses.
Authors: John Emery, M W32, Ataxia Telangiectasia, / Dal2, -A3+11 Da25=w30+w31, ; Da3l=part Of W16, ; Da34=lk, C Griscelli, M Schmid, J Dausset, Thomas Deeley, J Henk, I Evans, K James, T Priestman
Journal: BMJ (1974)

SIR,-The Brighton commnittee of inquiry into the death of Maria Colwell, keeping to its brief, has formulated an excellent report' which pinpoints deficiencies lin the co- ordination of agencies; but examination of the evidence shows that the lack of co- ordination was a subsidiary cause of the tragedy.The crucial decision to reimove thhe child from her affectionate foster-parents did not call 'for co-ordination between tihe agencies, nor did the decision by the court to support the return of the child to her natural parents.The second crucial decision, to leave the child in a situation of hazard, arose from the misinterpretation of albundant immediate data.Co-ordinating the informa- tion of other agencies was irrevelant.A nunrber of agencies had supporting evid- ence, but the unavailability of this evidence did not prevent neighibours coming to rhe right conclusions.Society, as your leading article (14 September, p. 641) states, did not fail.but the experts did.Using the public, the system, and the lack of co-ordination of agencies as scapegoats will not deceive in- formed opinion.We must look elsewhere
Visuomotor extrapolation
Authors: David Whitney
Journal: Behavioral and Brain Sciences (2008)

Abstract Accurate perception of moving objects would be useful; accurate visually guided action is crucial. Visual motion across the scene influences perceived object location and the trajectory of reaching movements to objects. In this commentary, I propose that the visual system assigns the position of any object based on the predominant motion present in the scene, and that this is used to guide reaching movements to compensate for delays in visuomotor processing.
Kaposi's Sarcoma, Vascular Permeability, and Scientific Integrity
Authors: Morris Reichlin
Journal: JAMA (1994)

<h3>To the Editor.</h3> —I am writing to congratulate you on the publication of the Brief Report by Dr Witte and colleagues.<sup>1</sup>As a veteran clinical investigator, I know how difficult it is to reconcile differences about scientific data, especially once they are published. On the other hand, such debate and reconciliation are essential to keep the integrity of the scientific enterprise at an acceptable level both for our own sense of truth and for the public's perception of us and their support of research. I am ashamed and embarrassed by the behavior of the editors of<i>Science</i>and proud and supportive of the editors of<i>JAMA</i>.
Prion Sensor
Authors: Tracy Hampton
Journal: JAMA (2008)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Diagnostic Value of the Forced Expiratory Time
Authors: Sunit R. Patel
Journal: JAMA (1994)

<h3>To the Editor.</h3> —Schapira et al<sup>1</sup>concluded that the forced expiratory time (FET) demonstrates moderately good performance as a diagnostic test for obstructive airways disease (OAD). In attempting to explain how we found the opposite to be true in a study of 205 plumbers and pipefitters,<sup>2</sup>the authors pinpointed their study group's advanced age and higher prevalence of disease. To assess the explanatory power of these two factors, we reanalyzed our data using the authors' criterion standard for OAD (forced expiratory volume at 1 second [FEV<sub>1</sub>%], less than 70%). Performing separate analyses for those subjects younger than 60 years and those older than 60 years we recalculated the sensitivity and specificity of FET at various cutoff values. Last, we relied on the authors' observed disease prevalence of 50% to determine FET's overall accuracy: (T<sup>+</sup>+T<sup>-</sup>)/(T<sup>+</sup>+F<sup>-</sup>+T<sup>-</sup>+F<sup>+</sup>) (Table). The tabulated data reveal that FET performed
Contrast Media
Authors: Elliott C. Lasser
Journal: JAMA (1966)

IN 1939, Holman<sup>1</sup>described a patient with multiple myeloma in whom renal failure developed following pyelography. It is not clear from this report whether the pyelography was of the retrograde or intravenous type, and renal failure did not occur until 8 to 12 days after the contrast study. While this case does not represent a bona fide instance of renal failure in multiple myeloma consequent to pyelography, it nevertheless alerted subsequent observers to the potential hazards of these procedures in such patients. What appears to be the first genuine case of acute renal failure following intravenous pyelography in a patient with myelomatosis was recorded by Bartels et al<sup>2</sup>in 1954. The contrast material utilized here was iodopyracet (Diodrast). Since that time, 14 additional cases have been recorded.<sup>3-11</sup>Of the 15 cases cited, 13 had intravenous pyelography and 2 had retrograde pyelography. Eight studies were carried out with
EXHIBIT OF THE ILLINOIS STATE BOARD OF HEALTH.
Journal: JAMA (1893)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Lupoid Hepatitis.
Authors: T. B. Reynolds
Journal: Annals of Internal Medicine (1964)

s1 October 1964Lupoid Hepatitis.T. B. Reynolds, M.D., F.A.C.P., Hugh A. Edmondson, M.D., F.A.C.P.T. B. Reynolds, M.D., F.A.C.P.Search for more papers by this author, Hugh A. Edmondson, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-61-4-804_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn 13 patients with chronic liver disease and positive LE cell tests, liver disease was usually insidious in onset and often far advanced when first discovered. Twelve of the patients were women, seven of whom were over 50 years of age. Characteristic laboratory findings were those of chronic liver disease, that is, albumin/globulin reversal, prothrombin depression, and marked transaminase elevation during episodes of jaundice.During the earlier stages of the disease, liver biopsies showed active focal liver necrosis, diffuse intralobular round cell infiltration, and connective tissue and round cell increase in the portal triads. In the later stages a coarsely... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: T. B. Reynolds, M.D., F.A.C.P.; Hugh A. Edmondson, M.D., F.A.C.P.Affiliations: Los Angeles, Calif. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 October 1964Volume 61, Issue 4Page: 804-804KeywordsBiopsyChronic liver diseaseConnective tissueConnective tissue diseasesHepatitisLiverLiver diseasesNecrosisNeutrophilsResearch laboratories ePublished: 1 December 2008 Issue Published: 1 October 1964 PDF downloadLoading ...
International Clinics;
Journal: JAMA (1893)

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Studies in Physiological Optics (Wilmer Institute), December 1928 to October 1934
Journal: JAMA (1935)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Unsuspected esophageal perforation
Authors: S. E. Vernon
Journal: JAMA (1978)

ESOPHAGEAL perforation has been seen more frequently in recent years because of the increased use of instrumentation as well as the increase in the number of surgical procedures performed on the esophagus.<sup>1</sup>Despite aggressive therapy, including surgical drainage and antibiotics, mortality remains high. If therapy is delayed, mortality is reportedly as high as 86%.<sup>2</sup>The following cases were recently seen at the University of California at Los Angeles (UCLA) and represent unsuspected perforations of an unusual cause with a fatal outcome. <h3>Report of Cases</h3><h3>Case 1.—</h3> An 81-year-old man was admitted to the UCLA Medical Center with a three-day history of left precordial pain associated with dyspnea. The pain was increased with deep inspiration and by lying on his left side. A "sore lump" in the throat was noted about one week before admission. Chest roentgenograms demonstrated an elevated left hemidiaphragm, with a left pleural effusion and cardiomegaly.
Consolidated List of Hospitals
Journal: JAMA (1960)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Anticoagulant Therapy
Authors: Claude O. Burdick
Journal: JAMA (1974)

<h3>To the Editor.—</h3> In the excellent article entitled "Anticoagulant Therapy—1974" (228:757, 1974), Dr. Wessler states that in the laboratory control of heparin therapy, it is critical that if an activated partial thromboplastin time (aPTT) is used, it must be standardized against the whole blood clotting time (WBCT). It might be inferred from this statement that it is possible to perform the two tests on a group of heparinized patients, and to determine a correlation coefficient high enough to substitute one test for another. This is probably not possible. Colman<sup>1</sup>did an excellent study attempting to do this very thing, and achieved a very weak coefficient of correlation of r =.62. Patients heavily heparinized by one standard were lightly heparinized by the other. By contrast, with two chemical tests purporting to measure the same variable, an r value above .95 would be expected before they were considered roughly interchangeable. The problem
British Journal of Ophthalmology, London
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Incorrect Name
Journal: JAMA (1989)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE NATIONAL ASSOCIATION OF MILITARY SURGEONS OF THE NATIONAL GUARD OF THE UNITED STATES.
Journal: JAMA (1891)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal