tbuckley/cabot-search huggingface dataset:
Correspondence
Authors: J. H. Apton
Journal: JAMA (1974)

<h3>Sir:</h3> I would like to disagree strongly with Dr. Chazan's review of Dr. Netter's book,<i>Kidneys, Ureters, and Urinary Bladder</i>, particularly with his sentence, "It would appear to me that there is no obvious audience for the book." (<i>JAMA</i>227:1065, 1974.) I feel strongly that no physician's personal library should be without the entire set. Artists like Dr. Netter have, through their brilliant pictorial work, contributed magnificently to the advancement of medical education. I can't think of anyone, whether medical student, generalist, or specialist, who could not profit enormously by having these volumes.
Surgeon General examines options for coping with public health menace of drunken driving
Authors: C. Marwick
Journal: JAMA (1988)

ANYTIME ALL 100 US senators can agree on something, it's news. The problem that's brought them to unanimous agreement: the public health menace of drunken driving. This week, Surgeon General C. Everett Koop, MD—who has been pondering the problem for some time—was expected to assign staff to develop a plan through which he and his successors can work with the states and other agencies to cope with the drunken driving menace. Koop has in hand a letter from senators, who call the situation a "national crisis." The one-page letter summarizes some statistics relating to alcohol-related road accidents: Two of five Americans will be involved in an alcohol-related accident at some point in their lives. Two million alcohol-related crashes occur in the United States each year at a cost of at least $10 billion to $15 billion annually. Alcohol is a factor in over half of fatal motor vehicle accidents. Every
Reporting drug side effects: signals and noise
Authors: J. Avorn
Journal: JAMA (1990)

The timely, accurate recognition of adverse drug reactions (ADRs) presents a fascinating and important challenge for the health care system. At the premarketing level, there must be a delicate balance in requiring clinical studies that are of adequate power to define the benefits and risks of a medication but that are not so cumbersome or lengthy as to drag on excessively, preventing the introduction of useful new agents into practice. The premarketing phase is complicated further by the fact that it is statistically impossible for large numbers of important high-risk patients to be included to answer every plausible question about adverse effects. In the case of the elderly, improvement still needs to be made in including sufficient numbers of typical "old" elderly, in addition to the 66-year-old all-stars sometimes presented as adequate geriatric representation. For some frail or demented elderly, as for pregnant women and children, ethical concerns may arise
Relation of body weight and insulin dose to the frequency of hypoglycemia. A report from the Boston Collaborative Drug Surveillance program
Journal: JAMA (1974)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Intestinal intubation
Authors: M. O. Cantor
Journal: JAMA (1968)

<h3>To the Editor:—</h3> For many years, I have admired the section inThe Journallabelled LETTERS. I consider this portion very important since it permits the reader to air his views briefly and to present interesting observations. In this latter category, is the letter by Drs. Herschman and Phillips (<b>204</b>:634, 1968). Unfortunately, the authors of the letter stated, "Intestinal intubation is frequently employed in the management of small-bowel obstruction, a procedure from which complications have not been reported." Many references in the literature report complications of all types as a result of intestinal intubation. Specifically, knot formation is relatively common, regardless of the type of tube used. It has been reported during the use of gastroduodenal tubes of all types as well as during the use of all types of long intestinal decompression tubes. The mechanism of knot formation consists of the insertion of too much tubing into the
O022 : The UK-PBC risk score: Derivation and validation of a risk score to predict liver events in the UK-PBC research cohort
Authors: M. Carbone, S.J. Sharp, M.A. Heneghan, J.M. Neuberger, G.M. Hirschfield, A.K. Burroughs, D. Thorburn, A. Bathgate, M. Aldersley, C. Adgey, P. Trembling, K. Williamson, L. Jopson, R.T. Lim, N.J. Wareham, H.J. Cordell, G.J. Alexander, J.E. Jones, R.N. Sandford, G.F. Mells
Journal: Journal of Hepatology (2015)
GAMMA GLOBULIN AS A PROPHYLACTIC IN POLIOMYELITIS
Journal: JAMA (1952)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
International Abstracts
Journal: JAMA (1992)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Medication Errors in Children
Authors: Jonathan D. Reich
Journal: JAMA (2001)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Culprit
Authors: Sedgwick Mead
Journal: JAMA (1982)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Journal of Immunology, Baltimore
Journal: JAMA (1969)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Pathogenic germline <i>BRCA1/2</i> mutations and familial predisposition to gastric cancer.
Authors: Hiroshi Ichikawa, Masayuki Nagahashi, Yoshifumi Shimada, Takaaki Hanyu, Takashi Ishikawa, Yusuke Muneoka, Yosuke Kano, Kazuyasu Takizawa, Kohei Miura, Yuki Hirose, Kizuki Yuza, Junko Tsuchida, Jun Sakata, Takashi Kobayashi, Hitoshi Kameyama, Hiroshi Yabusaki, Satoru Nakagawa, Shujiro Okuda, Kazuaki Takabe, Toshifumi Wakai
Journal: Journal of Clinical Oncology (2018)

e13618 Background: Approximately 5% of gastric cancer (GC) is associated with inherited cancer predisposition syndrome. Pathogenic germline BRCA1/2 mutations predispose, not only to breast and ovarian cancers but also other cancers. The aim of this study is to explore the association between germline BRCA1/2 mutations and familial GC (FGC). Methods: A total of seven Japanese GC patients whose tumors were revealed to have BRCA1/2 alterations by genomic sequencing were enrolled in this study. BRCA1/2 genetic testing and assessment of the pathogenicity of identified mutations were performed by Myriad Genetic Laboratories Inc. using genomic DNA extracted from peripheral blood samples. We assessed the family history according to the criteria for referral to genetic risk assessment and FGC defined by the International Gastric Cancer Linkage Consortium. Results: We identified pathogenic germline BRCA1/2 mutations in three patients with a familial component of GC. Case 1: A 73-year-old male with a BRCA2 mutation (c.89insA) developed metachronous multiple Lauren intestinal-type GC and synchronous hypopharyngeal cancer. He had a family history of cancers, with three GC and one BC in first- or second-degree relatives, which met the criteria for FGC. Case 2: A 66-year-old female with both BRCA1 (c.188T > A) and BRCA2 mutations (c.6922A > T) developed Lauren intestinal-type GC. She had a family history of GC, breast cancer and other cancers in first- or second-degree relatives, which did not fulfill the criteria for FGC. She had remarkable response to platinum therapy, with over five-year long-term survival after recurrence. Case 3: A 56-year-old male with a BRCA2 mutation (c.9310A > T) developed Lauren indeterminate-type GC. He had a family history of GC, with three cases in first- or second-degree relatives, which met the criteria for FGC. Conclusions: Pathogenic germline BRCA1/2 mutations may predispose to familial GC. Genetic testing for germline BRCA1/2 mutations in GC patients with a familial component may help to optimize medical care, including cancer surveillance and the selection of treatment modalities in the era of precision medicine.
International Conference on Prostaglandin and Lipid Metabolism in Radiation Injury
Journal: JNCI Journal of the National Cancer Institute (1986)

International Conference on Prostaglandin and Lipid Metabolism in Radiation Injury Get access JNCI: Journal of the National Cancer Institute, Volume 76, Issue 5, May 1986, Page 982, https://doi.org/10.1093/jnci/76.5.982-a Published: 01 May 1986
Tetanus—Kansas, 1993
Journal: JAMA (1994)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Some Applications of Categorical Data Analysis to Epidemiological Studies
Authors: James E. Grizzle, Gary G. Koch
Journal: Environmental Health Perspectives (1979)

Several examples of categorized data from epidemiological studies are analyzed to illustrate that more informative analysis than tests of independence can be performed by fitting models. All of the analyses fit into a unified conceptual framework that can be performed by weighted least squares. The methods presented show how to calculate point estimate of parameters, asymptotic variances, and asymptotically valid chi 2 tests. The examples presented are analysis of relative risks estimated from several 2 x 2 tables, analysis of selected features of life tables, construction of synthetic life tables from cross-sectional studies, and analysis of dose-response curves.
PRAGUE
Journal: JAMA (1934)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Smoking and risk of Graves' disease
Authors: M. F. Prummel
Journal: JAMA (1993)

<h3>Objective.</h3> —To assess if smoking is associated with Graves' disease and, if so, to ascertain whether this association persists when controlling for confounding factors. <h3>Design.</h3> —Consecutive entry case-control study with two age- and sex-matched control subjects from two different populations per case patient. <h3>Setting.</h3> —University hospital. <h3>Patients.</h3> —Five groups were studied: (1) Graves' ophthalmopathy and Graves' hyperthyroidism (n=100; divided in four subgroups according to the severity of the eye disease); (2) Graves' hyperthyroidism without clinical eye involvement (n=100); (3) sporadic nontoxic goiter (n=100); (4) autoimmune hypothyroidism (n=75); and (5) toxic nodular goiter (n=75). The study comprised 200 subjects from a hospitalbased population, and 200 from a population-based group served as control subjects. <h3>Main Outcome Measure.</h3> —Smoking status was determined from a questionnaire at the time of onset of the disease to exclude any effect of the disease itself on smoking. <h3>Results.</h3> —Smoking greatly increased the risk for Graves' ophthalmopathy (odds ratio, 7.7; 95% confidence interval, 4.3 to 13.7), but patients with Graves' hyperthyroidism alone were also more often smokers than control subjects (odds ratio, 1.9; 95% confidence interval, 1.1 to 3.2). Smoking was not associated with the other thyroid diseases studied. Essentially similar results were obtained after adjustment for differences in education between case patients and control subjects. Among the patients with Graves' ophthalmopathy, smokers had more severe eye disease than nonsmokers, but no association was found between the number of cigarettes smoked per day or the duration of smoking and the severity of the ophthalmopathy. However, there was a significant increase in the odds ratios in patients with more severe eye disease. <h3>Conclusions.</h3> —Smoking is associated with Graves' disease, and it especially increases the risk for the development of more severe ophthalmopathy. Thus, smoking appears to be one of the multiple factors inducing Graves' disease in genetically predisposed individuals. (<i>JAMA</i>. 1993;269:479-482)
Observations on Azeotrope of Fluoromar and Freon 113
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A novel tailored prognosis calculator for the individualized curative treatments allocation of HCC patients within the Mmilan criteria
Authors: Ningning Zhang, Wentao Jiang, Yamin Zhang, Tianqiang Song, Jiayu Lv, Jie Gu, Ying Wu, Jing Qian, Dazhi Tian, Qingjun Guo, Li Zhang, Jisan Sun, Yan Xie, Zhenglu Wang, Xin Sun, Zhongfang Yan, Yonghe Zhou, Yongjian Liu, Yibo Qiu, Bing Yang, Zhongyang Shen, Wei Lu
Journal: Journal of Hepatology (2020)
Constellation of risks and processes seen in search for Alzheimer's clues
Authors: P. Cotton
Journal: JAMA (1994)

THE SEARCH for the cause of Alzheimer's disease is sparking spirited debate. New ideas about the failure of apolipoproteins to bind to tau proteins, the main component of neurofibrillary tangles, are sharply criticized by most in the field, who have long placed blame on β amyloid, the main component of senile plaques. However, new evidence on many fronts suggests that there is probably not one single pathological route but rather several risk factors and pathological processes that, in various combinations, lead to the manifestations known as Alzheimer's disease (AD). Genes with roles in cancer as well as heart disease may be involved. So may sex hormones, growth factors, immune system responses, zinc, and apparently normal age-related changes, not alone but in concert with amyloid and tau. Many of these possibilities could offer therapeutic opportunities. For example, estrogen replacement therapy may reduce the risk of developing AD, and anti-inflammatory drugs might