tbuckley/cabot-search huggingface dataset:
Abstract 19468: Timing of Atrial Fibrillaiton-related Stroke and the Risk of All-cause Mortality
Authors: Parin J Patel, Ronit Katz, Jackson J Liang, Sanjay Dixit, David J Callans, Andrew E Epstein, Francis E Marchlinski, Rajat Deo
Journal: Circulation (2015)

Introduction: Strokes that occur after the onset of atrial fibrillation (AF) have a worse prognosis than strokes that do not occur in the setting of AF. Recent studies suggest that strokes that occur within several months prior to an AF diagnosis may be related to underlying, silent AF. Limited studies have evaluated survival differences between AF-related strokes that occur prior versus after AF diagnosis. Objective: We evaluated differences in the risk of all-cause death between patients that develop stroke in the 6 months before compared to any time after the diagnosis of AF. Methods: We utilized the University of Pennsylvania AF Free study to create an inception cohort of patients with incident stroke and AF. We assessed ECGs, clinical records, and administrative data within the health system over a 5 year period to identify individuals that had a first diagnosis of stroke or AF. Cox proportional hazards models evaluated associations between stroke subtypes and death. Results: We identified 3,616 individuals that developed stroke (323 had stroke after AF diagnosis, 292 patients had stroke within 6 months preceding AF diagnosis, and 2795 patients had stroke without an AF diagnosis). Of these patients, there were 319 all-cause mortality events over a median 4.6 [3.8, 5.5] years follow-up. The overall mortality rate was highest in patients that had a stroke within 6 months prior to AF (Table 1) and was almost 2-fold higher than those that had a stroke after an AF diagnosis (p&lt;0.001). After multivariable adjustment, patients with an AF-related stroke that occurred within 6-months prior to the diagnosis of AF had a significantly higher risk of death than those with stroke that occurred after an AF diagnosis or those with stroke but no AF (Table 1). Conclusions: Stroke that occurs prior to the diagnosis of AF was associated with a significantly higher risk of all-cause death. This increased mortality risk is not explained by the presence of other comorbid conditions.
NEW NAMES
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The nonspecific camel-hump sign
Authors: J. A. Abbott
Journal: JAMA (1976)

THE ELECTROCARDIOGRAPHIC "camel-hump" sign of Osborn,<sup>1</sup>a term first proposed by Harvey, is generally considered specific for hypothermia.<sup>2</sup>However, we recently saw a patient who had such a finding resulting not from hypothermia but from massive cerebral injury, indicating that this sign is nonspecific. To our knowledge, this is the second instance of central nervous system disease resulting in the camel-hump wave<sup>3</sup>(or, more accurately, dromedary wave) and the first with postmortem confirmation. <h3>Report of a Case</h3> An 8-year-old boy sustained a severe head injury when struck by a motorcycle while riding his bicycle. His growth and development had been normal. On admission, he was deeply comatose, and the pupils were fixed, dilated, and unresponsive to light; no papilledema was present. The blood pressure was 122/80 mm Hg and the pulse was 140 beats per minute and regular. There were left temporal ecchymoses and lacerations of the
Unexplained fevers in patients with nasotracheal intubation
Authors: A. R. Knodel
Journal: JAMA (1982)

Acute maxillary sinusitis developed in three critically ill patients whose conditions required mechanical ventilation. In all three, fever was the initial clinical manifestation. An obtunded state and an inability to speak delayed localization of the site of infection. Prolonged intubation, simultaneous use of nasal gastric tubes, poor healing, and large-diameter endotracheal tubes likely contributed to the disease pathogenesis. Acute maxillary sinusitis may be the cause of unexplained fevers in patients with nasotracheal intubation. (<i>JAMA</i>1982;248:868-870)
Ribodeoxyviruses and cancer
Authors: H. M. Temin
Journal: JAMA (1974)

Ribodeoxyviruses are viruses whose particles (virions) are enveloped and contain RNA and a DNA polymerase. Some of these viruses cause cancer, but most do not, nor any other disease. Ribodeoxyviruses replicate through a DNA intermediate, the DNA provirus. The DNA provirus can be assayed as infectious DNA. Because ribodeoxyvirus information can be present in cells as a part of the cell genome, it needs no viral functions for its maintenance. Therefore, ribodeoxyviruses often persist in cells with little or no viral gene expression. Most cancers in animals do not contain infectious ribodeoxyviruses, although they may contain ribodeoxyvirus genes and products. These same genes and products are, however, found with about the same frequency in normal cells, so that their presence in human tumors would not indicate an etiologic relationship between ribodeoxyviruses and human cancer. It has been suggested that ribodeoxyviruses and the genes for cancer evolve independently from a normal cellular system of DNA-to-RNA-to-DNA information transfer. (<i>JAMA</i>230:1043-1045, 1974)
Global Progress Toward Laboratory Containment of Wild Polioviruses—July 2001–August 2002
Journal: JAMA (2003)

Since the World Health Assembly launched the Global Poliomyelitis Eradication Initiative in 1988 (see box), the number of countries in which wild poliovirus is endemic has decreased from 125 to 10 in 2001. Three of the six World Health Organization (WHO) regions (Americas, European, and Western Pacific) have been certified as free of wild poliovirus transmission. The Global Commission for the Certification of the Eradication of Poliomyelitis will declare the world polio-free when all regions have documented the absence of wild poliovirus transmission for at least 3 consecutive years and when laboratories with wild poliovirus-containing materials have implemented appropriate containment conditions. This report describes preparations for laboratory containment and the creation of a global inventory of laboratories and institutions retaining wild poliovirus and summarizes global progress since July 2001. The data indicate that substantial progress has been made in identifying laboratories with wild poliovirus-containing materials and in conducting national wild poliovirus inventories.
Cutis marmorata telangiectatica congenita associated with an elevated maternal serum human chorionic gonadotrophin level and transitory isolated fetal ascites
Authors: C-P. CHEN, H-C. CHEN, F-F. LIU, S-W. JAN, S-R. CHERN, T-Y. WANG, H-Y. HUNG
Journal: British Journal of Dermatology (1997)
Abstract P046: The Subgingival Microbiome, Systemic Inflammation and Insulin Resistance
Authors: Ryan T Demmer, Alexander Breskin, Michael Rosenbaum, Aleksandra Zuk, Charles LeDuc, Rudolph Leibel, Bruce Paster, Moise Desvarieux, David Jacobs, Panos N Papapanou
Journal: Circulation (2016)

Introduction: Chronic inflammation is hypothesized as a mechanism linking microbial exposures to insulin resistance. We investigated the association between periodontal microbiota, systemic inflammation and insulin resistance among diabetes-free adults. Hypotheses: We hypothesized that subgingival microbial signatures would be related to both inflammatory phenotype and measures of insulin resistance and that there would be evidence of mediation by inflammatory markers. Methods: The Oral Infections, Glucose Intolerance and Insulin Resistance Study (ORIGINS) enrolled 152 diabetes-free adults (77% female) aged 20-55 years (mean=34±10). 304 subgingival plaque samples (2 per participant) were analyzed using the Human Oral Microbe Identification Microarray (HOMIM) to measure the relative abundances of 379 taxa from eight different phyla. C-reactive protein, interleukin-6, tumor necrosis factor-α and adiponectin were assessed from venous blood and their z-scores were summed to create an inflammatory score (IS). Fasting glucose and insulin levels defined insulin resistance via the HOMA-IR. Associations between the subgingival microbiota and both inflammation and insulin resistance were explored using multivariable linear regression models adjusted for cardiometabolic risk factors; mediation analyses assessed the proportion of the association explained by inflammation. Results: The IS was inversely associated with the relative abundance of Actinobacteria and Proteobacteria and positively associated with Firmicutes and TM7 (all p-values&lt;0.05). The IS was positively associated with glucose, insulin and HOMA-IR (all p&lt;0.05). Proteobacteria levels were associated with insulin resistance (p&lt;0.05). Inflammation explained 30%-98% of the observed associations between levels of Actinobacteria, Proteobacteria or Firmicutes and insulin resistance (p-values&lt;0.05). 18 individual taxa were associated with inflammation (p&lt;0.05) and 22 with insulin resistance (p&lt;0.05). Conclusion: Subgingival microbial community structure and membership were related to systemic inflammation and insulin resistance in a sample of diabetes-free adults.
Fifth International Symposium on the Prevention and Detection of Cancer
Journal: JNCI Journal of the National Cancer Institute (1981)

Journal Article Fifth International Symposium on the Prevention and Detection of Cancer Get access JNCI: Journal of the National Cancer Institute, Volume 67, Issue 6, December 1981, Page 1369, https://doi.org/10.1093/jnci/67.6.1369-b Published: 01 December 1981
Practical Cytology
Authors: Tilde S. Kline
Journal: JAMA (1968)

<b>Cytological Diagnosis in Medical Practice</b>, by J. Bamforth, 246 pp, 300 illus, $18.50, Boston: Little, Brown &amp; Co., 1967. Two rather short books on exfoliative cytology have appeared from Great Britain. The first,<i>Practical Cytology</i>by R. G. W. Taylor, is described by the author as a guide for students and technicians in the field. It is a very readable text for this audience. Included in its 148 pages is an excellent section on both cytologic and histologic fixation and staining techniques. There is a brief but pertinent section on chromosomes. Elementary cellular physiology and histology is well described as are terms frequently used in cytology. The actual presentation and discussion of exfoliative cytology of the various organs is extremely cursory—gynecologic cytology in 17 pages, sputa in 6 pages, etc. In fact, the description of gastric secretions, urine, breast, and cerebrospinal fluids is too brief for benefit. Nonetheless some of
THE NOSTRUM EVIL.
Journal: JAMA (1905)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Gynecology
Journal: JAMA (1998)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Medicolegal aspects of cardiopulmonary resuscitation (CPR) and emergency cardiac care (ECC)
Authors: K. M. McIntyre
Journal: JAMA (1980)

The National Conference on CPR and ECC that was held in Dallas in September 1979 developed standards and guidelines for the performance of ECC. Included was a panel on medicolegal aspects that defined areas of legal vulnerability and made certain recommendations. Two aspects of the medicolegal panel's deliberations deserve special attention by anyone involved in CPR and ECC. These two aspects involve (1) decision making, primarily the decisions to initiate, withhold, and terminate CPR, and (2) the quality of performance if the decision to initiate is made. <h3>Decision Making in CPR</h3> Decision making at the point of either initiation or termination of CPR is equivalent to defining whether the cardiac arrest victim should be pronounced dead or could and should be resuscitated. Guidelines for such decisions should be clear, consistent, and easy to implement. They should not be arbitrary. The touchstone of the legal propriety of such decisions is good
<i>A Manual of Medical Jurisprudence.</i>By Alfred Swaine Taylor, M. D., F. R. S. Revised and edited by Thomas Stevenson, M. D. Lond. Twelfth American edited, with citations and additions from the twelfth English edition, by Clark Bell, Esq., LL. D. Lea Brothers &amp; Co., New York and Philadelphia, 1897
Journal: American Journal of Psychiatry (1898)
Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4
Authors: Cristian Boboila, Catherine Yan, Duane R. Wesemann, Mila Jankovic, Jing H. Wang, John Manis, Andre Nussenzweig, Michel Nussenzweig, Frederick W. Alt
Journal: The Journal of Experimental Medicine (2013)
Statements from the International Committee of Medical Journal Editors
Journal: Annals of Internal Medicine (1991)

Editorials1 June 1991Statements from the International Committee of Medical Journal EditorsAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-114-11-989 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptOrder of AuthorsThe order of authorship is determined by the authors. All authors should meet the basic criteria for authorship (as stated elsewhere). Because order of authorship is assigned in different ways its meaning cannot be inferred accurately unless it is stated by the authors. Authors may wish to add an explanation of the order of authorship in a footnote. In deciding on order, authors should be aware that many journals limit the number of authors listed in the table of contents, and that the National Library of Medicine lists in MEDLINE only the first 10 authors.Protection of This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Members of the committee are Marcia Angell (The New England Journal of Medicine), Linda Hawes Clever (Western Journal of Medicine), Lois Ann Colaianni (Index Medicus), Robert Fletcher and Suzanne Fletcher (Annals of Internal Medicine), Robin Fox (The Lancet), Stephen Lock (British Medical Journal), George Lundberg (Journal of the American Medical Association), Magne Nylenna (Tidsskrift for den Norske Laegeforening), Arnold Relman (The New England Journal of Medicine), Povl Riis (Journal of the Danish Medical Association, Danish Medical Bulletin), Richard Robinson (New Zealand Medical Journal), Richard Smith (British Medical Journal), Bruce Squires (Canadian Medical Association Journal), and Laurel Thomas (Medical Journal of Australia). Please address comments to Dr. Angell (The New England Journal of Medicine) or Dr. Smith (British Medical Journal). PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byImpulsivity toward food reward is related to BMI: Evidence from intertemporal choice in obese and normal-weight individuals 1 June 1991Volume 114, Issue 11Page: 989-989KeywordsLibraries ePublished: 1 December 2008 Issue Published: 1 June 1991 PDF downloadLoading ...
Corrigendum: Mechanisms of Therapy Resistance in Patient-Derived Xenograft Models of BRCA1-Deficient Breast Cancer
Journal: JNCI Journal of the National Cancer Institute (2020)

The first sentence on page 2 should read, "Breast cancer affects approximately 1 million women each year and approximately 15% of all breast cancer cases are triple-negative breast cancers (TNBCs) (1)."The authors take responsibility for the error.
Defect in Medical Education
Journal: New England Journal of Medicine (1966)

It would be difficult to frame a more serious indictment of the whole system of medical education which is at present in vogue in England than is contained in the introductory address delivered at St. George's Hospital last week by Dr. Patrick Manson.He points out what, indeed, is evident enough to all who have to do with the students of the day, that the curriculum is decided by the examinations,
Postoperative adjuvant chemotherapy (CTX) use in patients (Pts) with stage II/III rectal cancer treated with neoadjuvant therapy: A National Comprehensive Cancer Network (NCCN) analysis.
Authors: P. Khrizman, J. C. Niland, A. ter Veer, D. Milne, K. Bullard Dunn, W. E. Carson, P. F. Engstrom, S. Shibata, J. M. Skibber, M. R. Weiser, D. Schrag, A. B. Benson
Journal: Journal of Clinical Oncology (2011)

3515 Background: Practice guidelines recommend that patients who receive neoadjuvant chemotherapy and radiation for locally advanced rectal cancer complete postoperative systemic chemotherapy irrespective of tumor downstaging. Methods: We used the NCCN Colorectal Cancer (CRC) Database which tracks longitudinal care for patients treated at 8 specialty cancer centers to evaluate how frequently rectal cancer pts treated with neoadjuvant chemoradiation receive postoperative systemic CTX. We examined patient and tumor characteristics associated with adjuvant CTX in a multivariable logistic regression model. Results: Between September 2005 and February 2010, 1,441 pts with stage II/III rectal cancer were enrolled. Of these, 810 pts received neoadjuvant chemoradiation and were included in the analysis. Of these, 159 pts (20%) did not receive any adjuvant CTX. For those seen by a medical oncologist, the most frequent reason chemotherapy was not recommended was due to co-morbid illness (54%) and the most frequent reason chemotherapy was not received even though it was recommended or discussed was due to patient refusal (73%). Pts who were more likely to have no adjuvant CTX administered included: age 75+ (OR=11.4, p<0.0001), ECOG PS ≥ 1 (OR=3.1, p=0.0009), on Medicaid or indigent (OR=3.6, p=0.02), complete pathologic response (cPR; OR=2.4, p=0.02), abnormal CEA post-operatively (OR=2.2, p<0.0001), unavailable CEA post operatively (OR=3.4, p<0.0001), presence of re-operation/wound infection (OR=2.7, p=0.03), and no closure of ileostomy/colostomy (OR=1.9, p=0.01). Conclusions: Even at specialty cancer centers, a sizeable minority of rectal cancer patients treated with curative intent neoadjuvant chemoradiation do not complete postoperative CTX. Strategies to foster adherence to the third and final component of curative intent treatment are necessary.
Myxoma of the Right Atrium with Polycythemia
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE HISTOLOGIC CHANGES PRODUCED BY THE VENOM OF POISONOUS SNAKES AND LIZARDS.
Journal: JAMA (1898)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal