tbuckley/cabot-search huggingface dataset:
Neonatal Goitre
Authors: C. S. Livingstone
Journal: BMJ (1966)

Complications of Intrauterine Devices SIR,-Intrauterine devices are being used extensively in India.I have fitted 1,500 Lippe's loops in my practice, which consists mostly of tea-garden workers.Breast feeding is the rule in this community up to two or three years.Sometimes the amenorrhoea continues into another pregnancy.In these cases it becomes very essential to select the proper time for the insertion of the "loop."An attempt is made to fit the device four to six weeks after delivery, or soon after the
Bronchial adenomas
Authors: F. Burcharth, C. Axelsson
Journal: Thorax (1972)

A series comprising 26 patients with bronchial adenoma, consisting of 23 carcinoid tumours, 2 mucoepidermoid tumours, and 1 cylindroma, treated during the period 1956-71 is presented. Eighteen of the carcinoid adenomas showed invasive growth, and six had metastases, five with lymph node metastases and one with hepatic metastases without node involvement (Case 17) at the time of operation. Both of the mucoepidermoid tumours and the cylindroma showed invasive growth, and one of the former had metastases. The average history of the patients was three to six months. The diagnosis was established preoperatively in 13 cases. It should be stressed that a cytological examination in 21 patients revealed pathological cells in seven. The patients have been treated according to the same principles followed in the case of malignant lung tumours. Four patients died owing to progression of the tumour, two from complicating diseases, and four from postoperative complications. Sixteen patients are alive and have been followed up. Three of these patients have been submitted to a non-curative operation. One year later they show no clinical signs of tumour progression. Twelve patients were submitted to a curative operation six months to 15 years before the follow-up. None shows any signs of recurrence. One patient refused operation. The five-year survival rate for lung carcinoids was 56%, or 68% after exclusion of four immediate postoperative deaths. It is concluded that bronchial adenomas are potentially malignant tumours and should be treated like other malignant lung tumours; because of their slow growth rate and the later development of metastases, extensive operations in cases of invasive tumours and reoperations in cases of recurrence may be carried out with good results. It is further concluded that cytological examinations have greater value than was hitherto assumed.
Cancer: Principles and Practice of Oncology, 5th Edition Vincent T. DeVita, Jr., Samuel Hellman, Steven A. Rosenberg, eds. Philadelphia:Lippincott-Raven Publishers, 1997.3125 pp., illus. $199. ISBN 0-397-51573-4
Authors: E. J. Seifter
Journal: JNCI Journal of the National Cancer Institute (1997)
The Treatment of Chronic Deafness by the Electrophonoïde Method of Zünd-Burguet.
Journal: JAMA (1931)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Injured Baby
Authors: L. Haas
Journal: BMJ (1965)

<h3>Abstract</h3> Aberrant lipid metabolism promotes the development of skeletal muscle insulin resistance, but the exact identity of lipid-mediated mechanisms relevant to human obesity remains unclear. A comprehensive lipidomic analyses of primary myocytes from lean insulin-sensitive (LN) and obese insulin-resistant (OB) individuals revealed several species of lysophospholipids (lyso-PL) that were differentially-abundant. These changes coincided with greater expression of lysophosphatidylcholine acyltransferase 3 (LPCAT3), an enzyme involved in phospholipid transacylation (Lands cycle). Strikingly, mice with skeletal muscle-specific knockout of LPCAT3 (LPCAT3-MKO) exhibited greater muscle lyso-PC/PC, concomitant with greater insulin sensitivity <i>in vivo</i> and insulin-stimulated skeletal muscle glucose uptake <i>ex vivo</i>. Absence of LPCAT3 reduced phospholipid packing of the cellular membranes and increased plasma membrane lipid clustering, suggesting that LPCAT3 affects insulin receptor phosphorylation by modulating plasma membrane lipid organization. In conclusion, obesity accelerates the skeletal muscle Lands cycle, whose consequence might induce the disruption of plasma membrane organization that suppresses muscle insulin action.
Practice of Medicine. Desk Index.
Journal: JAMA (1924)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
New England Journal of Medicine, Boston
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Sumatriptan
Authors: H Kaube, A May, H C Diener, V Pfaffenrath
Journal: BMJ (1994)

Making clinical informatics workEDrTOR,-We do not agree with Paul Lelliott's view that no existing hospital information system works.'At Burton Hospitals NHS Trust we have a totally integrated hospital information support system, which has been operating since April 1992.It provides many benefits for patients' care and for the wide range of staff who use it.We have married clinical activity (except for the doctor's record) with electronic recording on a hospitalwide basis and are now looking towards including doctors' notes.Our system is clinically biased as it is used by all clinical staff; it also provides all the information needed for administration, management, and
Treatment of injury to the root of the nail
Authors: S. Rodbard
Journal: JAMA (1968)

<h3>To the Editor:—</h3> Although addiction to amphetamine has been well known since 1958 when Connell<sup>1</sup>first published his clinical studies on amphetamine usage and amphetamine psychosis, addiction to Daprisal, a combination of amobarbital (32 mg), dextroamphetamine sulfate (5 mg), aspirin (0.16 gm), and phenacetin (0.16 gm), has only been recently appreciated.<sup>2</sup>Daprisal is generally regarded as a moodlifting analgesic for the relief of pain, prescribed for dysmenorrhea, pain of arthritis, rheumatism, headache, neuralgia, and nonspecific muscular disorders. The drug has become popular for the treatment of dysmenorrhea. The high risk of amphetamine dependency for young women has not been sufficiently emphasized. Lemere has mentioned Daprisal as an amphetamine-containing preparation with a likelihood of highdependency risk.<sup>3</sup>Ehtishamuddin has reported an addiction in a depressed woman who was taking six to eight tablets daily for several years.<sup>4</sup>Johnson and Milner have reported one case of addiction to this
JAMA Pediatrics
Authors: Phil Fontanarosa, Annette Flanagin, Brenda Gregoline, Tracy Frey, Kevin Brown, Amanda Ehrhardt, Iris Lo, M Newman, Suzanne Walker, Connie Manno, Sara Billings, Timothy Gray, Paul Ruich, Sam Wilder, Catherine Alden, Stephanie Beckmeyer, Jane Calayag, Jan Clavey, Mary Coerver-Connolly, Paula Glitman, Laura King, Regina Lilly, Joseph Mills, Brandy Patton, Rebecca Ritke, Thressa Smith, Donna Thordsen, Caroline Woods, Aggie Zarkadas, Wanda Assistant, Larry Bryant, Jacob Kendall-Taylor, Monica Mungle, Fanny Brown, Anna Bukowski, Lee Calibeo, Lenette Gardner-Gullens, Tosca Hall, Erin Kato, Rachell Lozano, Caroline Sietmann, Angelia Scientifi, Michael Berkwits, Eric Butkus, Michelle Kurzynski, Emily Ling, Jesse Mcquarters, Daniel Morrow, Reuben Rios, Carrie Butt, Mary Ferkaluk, Karen Bucher, Andy Rekito, Nick Reback, David Song, Deputy Livingston, Thomas Cole, Administration Director, Marla Hall, Deanna Willis, Yolanda Davis, Joseph Thornton, Deanna Bellandi, Jim Periodical, Thomas Easley, Brian Shields, Karen Adams-Taylor, Paul Gee, Monica Smith, Jeff Ery, J Bonistalli, Kathy Russell, Mirna Monal, Tim Melroy, Marketing Thornbury, Tricia Classifi, Anna Manager, Thalia Moss, Sade Deramus-Townsend, Tony Ralenkotter, Saskia Bolore, Gretchen Linder, Brian Mccartney, Christine Hearne, Natasha Staff, David Baum, Morgan Osgood, Ron Thomas, Rick Bell, Elizabeth Solaro, Sara Zimmerman, Geoff Rey, Fergus Clare, Lindsay Dawson, Ellen Gibson, Mustafa Ishaq, Sam Ismail, Peter Litton, Craig Mccaff Rey, Michael Mcgraw, Jon Perkins, Daniel Pickhardt, Romando Rossini, Sarah Subramanian, Stacy Business, Analyst Sirisha, Alluri Staff, Millette Jackson-Bates, Tom Miller, Ama Executives, James Madara, Bernard Hengesbaugh, Howard Bauchner, Dimitri Christakis, Ron Keren, Alison Galbraith, Megan Boston, Debra Madison, Houston Palazzi, Suzanne Seattle, Jennifer Matte, John Patrick, T Co, Aaron Carroll, Jay Berry, Thomas Boston, John Cincinnati, Morgantown Campo, Virginia West, Wright Ellen, Nashville Clayton, Mitchell Cohen, Alabama Leonard, H Epstein, New York, Tracy Lieu, Aaron California, Maryland Baltimore, Shawn Rangel, Msce Boston, Susan Rosenthal, Martha Sola-Visner, Maria Trent
Journal: JAMA Pediatrics (2019)

Vision JAMA Pediatrics will be the most respected source of information for investigators, providers, and policy makers seeking the highest quality evidence to guide decision making.Mission Statement JAMA Pediatrics seeks to provide state-of-the-art information to individuals and organizations working to advance the health and well-being of infants, children, and adolescents.The journal also provides a forum for discussion of the most important issues and policies aff ecting child and adolescent health and health care.
New Zealand Medical Journal, Wellington
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Myocardial infarction and erythema multiforme
Authors: C. G. Kardinal
Journal: JAMA (1968)

<h3>To the Editor:—</h3> A letter in the<i>American Journal of Hospital Pharmacy</i>(<b>25</b>:34, 1968) by Sydney L. Burgee, Jr., pointed out that local anesthetics of several kinds, especially procaine hydrochloride, tetracaine hydrochloride, and lidocaine hydrochloride, react with the agents used to determine protein content of cerebrospinal fluid, giving a false high reading, when the colorimetric test uses the Folin-Ciocalteau reagent. Procaine or tetracaine (0.1 cc of a 1% solution) give a "protein" reading of 972 mg/100 cc! Thus, if only 0.1 cc of procaine or tetracaine happens to be mixed in 1 cc of cerebrospinal fluid, the protein reading would be approximately 100 mg/100 cc. I think it should be brought to the attention of physicians who are doing spinal taps. I have seen many physicians inject some of the local anesthetic through the spinal needle as it neared the spinal canal. If the needle happened to be filled
Abstract 4448: Fecal miRNA test using microRNA expressions of exfoliated colonocytes for colorectalcancer screening
Authors: Yoshikatsu Koga, Masahiro Yasunaga, Yasuhiro Matsumura
Journal: Cancer Research (2012)

Abstract Background &amp; Aims: To reduce the mortality rate of several cancers, the development of a screening test is needed. We have been developing new screening methods for colorectal cancer (CRC) by applying molecular biological tools to exfoliated colonocytes. In the last few years especially, we have reported the fecal RNA test including the CRC-related gene expression analysis. Here, we investigated the potential of a fecal miRNA test for the early detection of CRC. Methods: CRC patients (n = 299) and healthy volunteers (n = 116) with no abnormalities detected by screening colonoscopy were enrolled in this case control study. The miRNA expressions in the colonocytes of CRC patients (n = 47) and healthy volunteers (n = 35) were analyzed in the training study and the miRNA expressions in the colonocytes of CRC patients (n = 252) and healthy volunteers (n = 81) were validated in the validation study. First, CRC related oncogenic miRNAs for CRC detection were selected by TaqMan MicroRNA Array v3.0 (corresponded to miRBase release 14). Next, the expressions of the most suitable oncogenic miRNAs were analyzed by quantitative real-time PCR in the training study. Lastly, the sensitivity and specificity of fecal miRNA test was validated by quantitative real-time PCR in the validation study. Results: According to the results of miRNA array, 20 miRNAs were selected as candidate of miRNA analysis. In the training study, significant differences in the relative expression level of miR-17, -18a, -19a, -19b, -20a, -92a, -106a, -135a, -135b, and -146a were observed between the CRC patients and the healthy volunteers (P &amp;lt; 0.01). On the other hand, there was no significant difference in the relative expression level of miR-21, -183, -223, and -454* between the CRC patients and the healthy volunteers (P &amp;gt; 0.1) AUC of ROC curve using miR-17, -18a, -19a, -19b, -20a, -92a, -106a, -135b, and -146a were more than 0.7. The overall sensitivity and specificity in the training study using these miRNAs were 70.2% (33/47) and 74.3% (26/35), respectively. The overall sensitivity and specificity in the validation study were 67.5% (170/252) and 75.3% (61/81), respectively. Conclusions: We selected the suitable miRNAs for CRC detection in exfoliated colonocytes. Fecal miRNA test may be useful for CRC screening. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 103rd Annual Meeting of the American Association for Cancer Research; 2012 Mar 31-Apr 4; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2012;72(8 Suppl):Abstract nr 4448. doi:1538-7445.AM2012-4448
The SUPPORT project and improving care for seriously ill patients
Authors: M. S. Strong
Journal: JAMA (1996)

<h3>To the Editor.</h3> —The SUPPORT project<sup>1</sup>seems to place the blame for the demonstrated breakdown in communication between physicians and patients squarely on the caregiver. Is this fair? I have spent much of the last 20 years working to empower people to take control of how they are cared for at the end of life. In so doing, I have met many caring nurses and physicians and seen the situations with which they are faced. If I were a physician in a hospital setting, I would hesitate to initiate the subject of end-of-life care if I had never communicated on such a difficult issue with the patient at an earlier time in a less-threatening setting. We must devise the means to make end-of-life care easier to broach. I suggest that when a patient arrives for an appointment with his or her physician, the patient can be asked to fill
The muse and the martini
Authors: D. W. Goodwin
Journal: JAMA (1973)

Georges Simenon started keeping notebooks when he was nearing 60 and feeling gloomy. The notebooks were published ten years later under the title<i>When I Was Old</i>. By this time he had stopped feeling gloomy and stopped keeping notebooks. It is too bad about the latter. The notebooks tell a lot about writing. They also tell a lot about drinking. Simenon had vast experience with both. Simenon is a great and honest writer. Some European critics believe he deserves the Nobel Prize. Most Americans think of him as a detective story writer, the creator of Inspector Maigret. This is unfair. Fewer than half of his several hundred novels are about Maigret, and the best "Maigrets" are fine novels, not who-doneits at all. John Raymond, a literary critic for the<i>London Times</i>, calls Simenon the greatest storyteller of our day. Gide, Hemingway, and other famous writers have praised him extravagantly. Because
Acta Rheumatologica Scandinavica, Stockholm
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Isozymes of lactic dehydrogenase in human tissues
Journal: Journal of Clinical Investigation (1961)

apy.The data suggest that excess of calcium, rather than the agent or disease process producing it, is ultimately responsible for the defect.The concentrating defect was not attributable to an increased solute excretion, which showed negligible changes with improvement.All subjects but one showed normal sodium conservation with urinary sodium less than 9 mEq per day at this intake, suggesting that the concentrating defect does not depend upon gross failure of sodium transport.
Hematopoietic Stem Cell Transplantation for Hemophagocytic Lymphohistiocitosis : A National Retrospective Analysis of Data from the Italian Association of Pediatric Hematology Oncology (AIEOP)
Authors: Chiara Messina, Marco Zecca, Franca Fagioli, Attilio Rovelli, Edoardo Lanino, Alice Bertaina, Porta Fulvio, Maurizio Aricò, Elena Sieni, Mimmo Ripaldi, Claudio Favre, Marta Pillon, Marco Rabusin, Simone Cesaro, Maurizio Caniglia, Paolo Di Bartolomeo, Ottavio Ziino, Francesco Saglio, Arcangelo Prete, Franco Locatelli
Journal: Blood (2015)
Distinct Roles for Donor and Host Antigen Presenting Cells and Costimulatory Molecules in Murine Chronic Graft-Vs-Host Disease: Requirements Depend on Target Organ.
Authors: Britt Anderson, Jennifer McNiff, Dhanpat Jain, Bruce R. Blazar, Warren D. Shlomchik, Mark J. Shlomchik
Journal: Blood (2004)
REMOVAL OF SMALLPOX PITTING
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal