tbuckley/cabot-search huggingface dataset:
New Names
Journal: JAMA (1971)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 9952: Myocardial PtiO2 is a More Reliable Variable Than FFR, Showing High Potential for Clinical Application in Assessing Myocardial Ischemia Caused by Coronary Artery Stenosis
Authors: Ri-ichiro Kakihara, Manami Inayoshi, Chinatsu Naruse
Journal: Circulation (2015)

Background: A patient of effort angina who had 75% stenosis at #7 with high FFR 0.85 underwent PCI. He has had no chest pain at all since PCI. Purpose: To find a more reliable variable than FFR in assessing myocardial ischemia (MI) caused by coronary artery stenosis (CAS), animal experiments were done to cover three variables - coronary blood flow (Flow), myocardial PtiO2 (PtiO2) and FFR, which were compared to see which is the most reliable of the three. All the procedures were approved by Clinic’s ethical committee and carried out observing the Declaration of Helsinki of the World Medical Association. Method: In twelve pigs, vascular occuluders and flow meters were set at #6 and/or #7 and #11 and/or #13. PtiO2 sensor wires were inserted into the anterior and lateral LV wall transepicardially. FFR sensor wires were placed across the LAD and LCX stenoses. The data was all analyzed by a paired t-test and ROC. Results: Flow(ml/min): normal 54.23±5.24 and 50% 27.88±5.53, p&lt; 0.0001; sencitivity(sen.) 1.00, specificity(spe.) 1.00, accuracy(acc.) 1.00 by ROC 38.9. 50% and 75% 17.60±6.06, p &lt; 0.0001; sen. 0.92, spe. 0.83, acc. 0.88 by ROC 21.8. PtiO2(mmHg) : normal 54.91±6.44 and 50% 27.87±3.40, p&lt; 0.0001; sen. 1.00, spe 1.00, acc. 1.00 by ROC 32.1. 50% and 75% 16.85±2.73, p &lt; 0.0001; sen. 0.92, spe. 0.92, acc. 0.92 by ROC 21.7. FFR: normal 0.97±0.01 and 50% 0.89±0.06, p &lt; 0.0001; sen. 0.92, spe. 1.0, acc. 0.96 by ROC 0.96. 50% and 75% 0.83±0.04. p &lt; 0.0002; sen. 0.75, spe. 0.75, acc. 0.75 by ROC 0.86. Thus PtiO2 was the most reliable variable in assessing MI of CAS among three. To confirm clinical application of PtiO2 , animal experiments using ten pigs was conducted to measure it through coronary artery. 0.5 mm transepicardial sensor wires were attached to the tips of upside-down 0.014 inch guiding wires. The guiding wires perforated LADs and were pushed into myocardium to measure PtiO2 (normal 55.54±3.57, 50% 28.08±2.48, 75% 17.1±2.85). These data showed no significant difference from the transepicardial data described above. A leak of contrast agent through a tiny perforation had expired in ten minutes. Conclusion: The results proved PtiO2 was the more reliable valiable than FFR, showing high potential for clinical application in safely assessing MI caused by CAS.
Secondary Hypertension Due to Primary Hyperreninism
Journal: JAMA (1973)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
X-Ray Therapy of Chronic Arthritis (Including the X-Ray Diagnosis of the Disease). Preliminary Report Based on 100 Patients Treated at Quincy, Illinois
Journal: JAMA (1941)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Making the Connection
Authors: Allison R. Schulman, Anand Vaidya, Ali Tavakkoli, Kunal Jajoo, Marvin Ryou
Journal: New England Journal of Medicine (2017)

A 41-year-old man with hyperlipidemia and a history of morbid obesity since childhood was referred to a surgeon for a weight-management consultation and consideration of bariatric surgery. The patient had tried dieting on his own and had also tried several commercial weight-loss programs with little long-term success. He reported eating foods high in carbohydrates when he was nervous . . .
Contrast nephrotoxicity.
Authors: B J Barrett
Journal: Journal of the American Society of Nephrology (1994)

Iodinated contrast media have some nephrotoxic potential but rarely cause significant renal failure in patients with normally functioning kidneys. Patients with existing renal impairment, with or without diabetes, those with current congestive heart failure of Class III or IV, those with reduced effective arterial volume (e.g., nephrotic, cirrhotic), or those receiving drugs that may impair renal function or increase contrast nephrotoxicity are at higher risk. Contrast nephrotoxicity may be clinically important in patients with other factors simultaneously affecting the renal response to contrast or in whom acute renal failure would seriously affect prognosis. The pathogenesis of contrast nephrotoxicity probably involves a combination of direct tubular toxicity and renal ischemic injury. Knowledge of the pathogenetic pathways is accumulating and is leading to the discovery of rational specific prophylactic measures to reduce the burden of nephrotoxicity. After the efficacy of these measures has been established, they should be considered for use in patients at high risk. Existing data indicate a limited role for the newer low-osmolality media for the prevention of nephrotoxicity.
Treatment with Recombinant Human Insulin-Like Growth Factor (rhIGF)-I/rhIGF Binding Protein-3 Complex Improves Metabolic Control in Subjects with Severe Insulin Resistance
Authors: Fiona M. Regan, Rachel M. Williams, Anna McDonald, A. Margot Umpleby, Carlo L. Acerini, Stephen O'Rahilly, Roman Hovorka, Robert K. Semple, David B. Dunger
Journal: Endocrine Reviews (2010)

ObjectiveDiabetes in the context of severe insulin resistance (SIR) presents a major therapeutic challenge because conventional therapies including insulin and insulin sensitizers often fail to achieve adequate metabolic control. Adjunctive therapy with recombinant human IGF-I (rhIGF-I)/recombinant human IGF binding protein-3 (rhIGFBP-3) has been shown to improve insulin sensitivity in both type 1 and type 2 diabetes and may have a role in the treatment of SIR. We report clinical and physiological outcomes after adjunctive therapy with rhIGF-I/rhIGFBP-3 in five subjects with SIR.
Gastroc Dilation.
Journal: JAMA (1884)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
JAMA Journal Club
Journal: JAMA (1992)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A Course of Lectures on Surgery: Delivered in the Medical School of Cambridge
Authors: G. M. Humphry
Journal: BMJ (1849)

Atrophy from Inflammation, probably in part dependent directly on the Inflammatory Process, though selkom entirely so: Softening, sometimes the only evidence of InJlammation discoverable a,fter death,-not the mere result of edemna, or of impaired nutrition, but a direct effect of Inflammation; Softeningfrom other causes.Cases in which Softening from Inlammnation most quickly occurs; Chronic softening, Yielding of Bones, Ligarmnts, 4rc.; Interstitial Absorption witnessed in Bones and Carlilages.-Ulceration,nature of the process; its difference from Suppuration; Healing by Granulation, Cicatrization, and Contraction; advan- tages and disadvantages of the latter; Peculiarity of Ulcers in the Cornea, and in Cartilage; CasiJfication of Ulcers into Inflammatory, Phagedenic, andAtonic; Inflanmatory Ulcers, proportionate in their progress to the Accompanying InJlammation; may be Acute or Chronic} Acute Ulcers; Chronic Ulcers; causes of their frequent occurrence in the Skin of the Legs, their General Characters and Treatment; their frequnt Relation to Disordered state of Constitution; Ulcers under Thickened Cuticle.The destructive effects of inflammation are most quickly produced, and are most marked in those tissues which are endued with the greatest vascularity and delicacy of structure, such as the nervous centres, the intemal organs, mucous membranes and the skin; and, secondly, in those tissues whose vitality is naturally low, such as the fibrous membranes and bone, or whose nutritive and reparative energies have been reduced by some former disease or accident.They are most marked in corresponding ages and habits of body, that is to say, in infants, and persons of excessive fineness and delicacy of physical formation on the one hand, and in the aged, the debilitated, or the infirm on the other.They consist of atrophy, softening, interstitial absorption, ulceration, and mortification.No. II, May 30, 1849.
Nystagmus: Recent Studies
Journal: JAMA (1969)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Book Review The Extra-Ocular Muscles: A clinical study of normal and abnormal ocular motility . By Luther C. Peter, M.D., Sc.D., LL.D. Third edition, thoroughly revised. 8°, cloth, 368 pp., with 147 illustrations and 5 color plates. Philadelphia: Lea and Febiger, 1941. $4.50.
Journal: New England Journal of Medicine (1941)
Unexplained Noncardiac Chest Pain
Authors: Colin Reisner
Journal: Annals of Internal Medicine (1997)

Letters15 April 1997Unexplained Noncardiac Chest PainColin Reisner, MD and U.G. Mason III, MDColin Reisner, MDYale University School of Medicine, New Haven, CT 06877University of Colorado School of Medicine, Denver, CO 80262Search for more papers by this author and U.G. Mason III, MDYale University School of Medicine, New Haven, CT 06877University of Colorado School of Medicine, Denver, CO 80262Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-126-8-199704150-00023 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:We read with interest the two articles on unexplained chest pain and its potential relation to esophageal dysfunction [1, 2] and the accompanying editorial [3]. We believe that one possible cause of unexplained chest pain that may be overlooked is vocal cord dysfunction. We recently reported a case of unexplained chest pain attributed to vocal cord dysfunction [4]. The patient was a 41-year-old woman who was referred to our institution for further evaluation of “chest tightness” that presented as unstable angina. Her symptoms consisted of chest tightness, pain radiating to her neck and left arm, and shortness ...References1. Rao SS, Gregersen H, Hayek B, Summers RW, Christensen J. Unexplained chest pain: the hypersensitive, hyperreactive, and poorly complaint esophagus. Ann Intern Med. 1996; 124:950-8. Google Scholar2. Frobert O, Funch-Jensen P, Bagger JP. Diagnostic value of esophageal studies in patients with angina-like chest pain and normal coronary angiograms. Ann Intern Med. 1996; 124:959-69. Google Scholar3. Goyal RK. Changing focus on unexplained esophageal chest pain [Editorial]. Ann Intern Med. 1996; 124:1008-11. Google Scholar4. Reisner C, Mason UG. Vocal cord dysfunction with reactive airways disease presenting as unstable angina. Ann Allergy. 1996; 76:78. Google Scholar Author, Article, and Disclosure InformationAffiliations: Yale University School of Medicine, New Haven, CT 06877University of Colorado School of Medicine, Denver, CO 80262 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 15 April 1997Volume 126, Issue 8Page: 662-663KeywordsImmunologyIschemiaLarynxMethacholine challengeNervesNociceptorsPainSteroidsThoraxUnstable angina Issue Published: 15 April 1997 CopyrightCopyright © 1997 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...
Association between Air Pollution and Low Birth Weight: A Community-Based Study
Authors: Xiaobin Wang, Hui Ding, Louise Ryan, Xiping Xu
Journal: Environmental Health Perspectives (1997)

The relationship between maternal exposure to air pollution during periods of pregnancy (entire and specific periods) and birth weight was investigated in a well-defined cohort. Between 1988 and 1991, all pregnant women living in four residential areas of Beijing were registered and followed from early pregnancy until delivery. Information on individual mothers and infants was collected. Daily air pollution data were obtained independently. The sample for analysis included 74,671 first-parity live births were gestational age 37-44 weeks. Multiple linear regression and logistic regression were used to estimate the effects of air pollution on birth weight and low birth weight (< 2,500 g), adjusting for gestational age, residence, year of birth, maternal age, and infant gender. There was a significant exposure-response relationship between maternal exposures to sulfur dioxide (SO2) and total suspended particles (TSP) during the third trimester of pregnancy and infant birth weight. The adjusted odds ratio for low birth weight was 1.11 (95% CI, 1.06-1.16) for each 100 micrograms/m3 increase in SO2 and 1.10 (95% CI, 1.05-1.14) for each 100 micrograms/m3 increase in TSP. The estimated reduction in birth weight was 7.3 g and 6.9 g for each 100 micrograms/m3 increase in SO2 and in TSP, respectively. The birth weight distribution of the high-exposure group was more skewed toward the left tail (i.e., with higher proportion of births < 2,500 g) than that of the low-exposure group. Although the effects of other unmeasured risk factors cannot be excluded with certainty, our data suggests that TSP and SO2, or a more complex pollution mixture associated with these pollutants, contribute to an excess risk of low birth weight in the Beijing population.
Abstracts of the Annual Meeting of The Endocrine Society
Journal: Endocrine Reviews (1981)

Journal Article Abstracts of the Annual Meeting of The Endocrine Society Get access Endocrine Reviews, Volume 2, Issue 4, 1 October 1981, Page 461, https://doi.org/10.1210/edrv-2-4-461 Published: 01 October 1981
Surgery, St. Louis
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal