New Studies Do Not Challenge the American College of Cardiology/American Heart Association Lipid Guidelines
Authors: Timothy P. Hofer, Rodney A. Hayward
Journal: Annals of Internal Medicine (2016)

Letters6 December 2016New Studies Do Not Challenge the American College of Cardiology/American Heart Association Lipid GuidelinesTimothy P. Hofer, MD and Rodney A. Hayward, MDTimothy P. Hofer, MDFrom Veterans Affairs Center for Clinical Management Research and University of Michigan Institute of Health Policy and Innovation, and National Clinician Scholars Program, University of Michigan Institute for Health Policy and Innovation, Ann Arbor, Michigan. and Rodney A. Hayward, MDFrom Veterans Affairs Center for Clinical Management Research and University of Michigan Institute of Health Policy and Innovation, and National Clinician Scholars Program, University of Michigan Institute for Health Policy and Innovation, Ann Arbor, Michigan.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/L16-0417 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:Dr. Whayne reiterates some common concerns about the new guidelines from the American College of Cardiology and the American Heart Association, namely, that they somehow undermine the LDL-C hypothesis, will cause PCPs to undertreat high-risk patients, and will take too much time relative to a treat-to-target approach. Of note, he nevertheless suggests what sounds like a potentially even more complex approach whereby PCPs should have a "plan tailored to [each patient's] individual clinical status with a different LDL-C target for each person."We clearly state that the evidence we cited supporting the benefit-based treatment approach was based on ...References1. Hayward RA, Krumholz HM, Zulman DM, Timbie JW, Vijan S. Optimizing statin treatment for primary prevention of coronary artery disease. Ann Intern Med. 2010;152:69-77. [PMID: 20083825]. doi:10.7326/0003-4819-152-2-201001190-00004 LinkGoogle Scholar2. Sussman J, Vijan S, Hayward R. Using benefit-based tailored treatment to improve the use of antihypertensive medications. Circulation. 2013;128:2309-17. [PMID: 24190955] doi:10.1161/CIRCULATIONAHA.113.002290 CrossrefMedlineGoogle Scholar3. Wright JT, Williamson JD, Whelton PK, Snyder JK, Sink KM, Rocco MV, et al; SPRINT Research Group. A randomized trial of intensive versus standard blood-pressure control. N Engl J Med. 2015;373:2103-16. [PMID: 26551272] doi:10.1056/NEJMoa1511939 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Veterans Affairs Center for Clinical Management Research and University of Michigan Institute of Health Policy and Innovation, and National Clinician Scholars Program, University of Michigan Institute for Health Policy and Innovation, Ann Arbor, Michigan.Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M15-2428. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoNew Studies Do Not Challenge the American College of Cardiology/American Heart Association Lipid Guidelines Timothy P. Hofer , Jeremy B. Sussman , and Rodney A. Hayward New Studies Do Not Challenge the American College of Cardiology/American Heart Association Lipid Guidelines Thomas F. Whayne Jr Metrics Cited byOn P values and effect modificationWhen to Start a Statin Is a Preference-Sensitive Decision 6 December 2016Volume 165, Issue 11Page: 827-828KeywordsBlood pressureDisclosureHeartLipidsLongitudinal studiesLow density lipoprotein cholesterolRisk assessmentsStatinsSystolic pressureTreatment guidelines ePublished: 6 December 2016 Issue Published: 6 December 2016 Copyright & PermissionsCopyright © 2016 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...