tbuckley/cabot-search huggingface dataset:
THE ATLANTIC CITY SESSION
Journal: JAMA (1907)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Reply
Authors: E Elias, R Laitt
Journal: Gut (1993)

Letters the appreciable differences seen in the results.The studies of Lauritsen et al, with faecal dialysates reflect only the intraluminal concen- trations but provide no information about the intramucosal concentrations.The information that results from both types of studies, how- ever, can be complementary.Finally, we totally agree that the very low mucosal concentrations of 5-ASA after Salazopyrin supports the hypothesis that Salazopyrin has pharmocological properties that are different from those of 5-ASA and contribute to its therapeutic efficacy.
Illustrations of the Different Forms of Insanity
Authors: W. H. O. Sankey
Journal: BMJ (1863)

adopted in cases where the epidemic disorders have seized on suffering humanity.We ought neither to hesi- tate, nor pautse, nor tire, until we have determirned some means, definite in their design, by which some reduc- tion of their 25 per cent. of mortality shall be secured.At thie present moment our practice, althouigh successful in regsard to symptoms of a superficial kind, is vague, contradictory, and unsatisfactory.It will remain thlus Brts
Rapid eye movement sleep behavior disorder. A treatable parasomnia affecting older adults
Authors: C. H. Schenck
Journal: JAMA (1987)

Rapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia defined by intermittent loss of electromyographic atonia during REM sleep with emergence of complex and vigorous behaviors. Punching, kicking, and leaping from bed during attempted dream enactment caused repeated injury in nine of our first ten adult patients. Mean age at onset was 62 years; nine of the patients were male. All patients underwent standard polysomnographic studies with videotaping of behaviors and extensive neurologic and psychiatric evaluations. The RBD was unrelated to psychopathologic conditions but in five cases was closely linked with major neuropathologic disorders: dementia (two), olivopontocerebellar degeneration, subarachnoid hemorrhage, and the Guillain-Barré syndrome. Other common polysomnographic abnormalities were high REM density, increased stage 3/4 (slow-wave) sleep, and both periodic and aperiodic limb twitching in non-REM sleep. Eight patients had dream changes involving motor overactivity and violent confrontations of dream characters. Clonazepam induced rapid and sustained improvement of dream and sleep behavior problems in seven patients, as did desipramine hydrochloride in one patient. (<i>JAMA</i>1987;257:1786-1789)
Individual dietary advice has modest effects on cholesterol
Journal: BMJ (1998)

Early selegiline treatment in Parkinson's disease may not be advantageous A previous report from the UK Parkinson's Disease Research Group's randomised controlled trial noted that patients with early, mild Parkinson's disease treated with selegiline and levodopa (arm 2) had around 60% increased mortality compared with those given levodopa alone (arm 1).On p 1191 Ben-Shlomo et al examined whether this increased mortality was maintained and tested possible explanations such as orthostatic hypotension, more rapidly deteriorating disease, and adverse drug interactions with other drugs.The extended results show a persistent but smaller excess mortality with combined treatment.Patients who died in arm 2 were more likely to have had possible dementia before death.The results do not support the use of combined treatment in newly diagnosed disease.In more advanced disease its avoidance in patients with postural hypotension, frequent falls, confusion, and dementia may be advisable.
P01.135 User experience with new, aesthetically improved transducer arrays for delivery of tumor treating fields for glioblastoma
Authors: A Kinzel, M Graeb, J Grewal, E Kirson
Journal: Neuro-Oncology (2018)

Tumor Treating Fields (TTFields) are low-intensity, intermediate frequency alternating electric fields for glioblastoma treatment. TTFields are administered using the Optune® system, comprised of two main components - an electric field generator and insulated transducer arrays (TAs). The current TAs consist of 2 opposing pairs of TAs having ceramic disks arranged within a white adhesive bandage, designed to hold the TAs tightly to the shaved scalp. In response to patient and healthcare provider requests, NovocureTM evaluated tan colored TAs to minimize the stark appearance of white TAs for patients, making the TAs more amenable for use in public settings. This study was carried out in 25 newly diagnosed and recurrent GBM patients in Germany receiving Optune. Patients with KPS ≥70, caregiver support and skin intact at study initiation were asked to complete a questionnaire, which assessed patient satisfaction with the comfort, aesthetics and convenience associated with the tan TAs. Patients reported responses to questionnaire at day 0 (white arrays), days 7 and 28 (wearing the tan arrays). Median patient reported changes from baseline to Day 28 in responses in the questionnaire were compared using a Wilcoxon signed rank test. Patients reported the color of TAs to be an important attribute (p<0.011). The tan arrays were less conspicuous than white arrays (p<0.0052). Participants in Germany found tan color was neither too dark nor too light (p<0.001). Participants felt that wearing the tan arrays were significantly cooler than the white arrays. Optune is designed to be integrated into patients’ daily life. Results from phase 3 clinical trials showed a correlation between efficacy of TTFields and daily treatment duration. Therefore, improvements addressing patients’ user experience with the tan colored TAs, which minimize calling attention to the patients’ medical condition, may help to further improve treatment compliance and patient satisfaction.
Tuberculosis as a Manifestation of the Acquired Immunodeficiency Syndrome-Reply
Authors: Lee B. Reichman
Journal: JAMA (1986)

<h3>In Reply.—</h3> I appreciate the comments of Guarner et al. More investigators are noting serious<i>M tuberculosis</i>disease in persons infected with HIV with risk factors other than intravenous drug abuse. In addition to Guarner et al, Schecter et al<sup>1</sup>have also reported this, and I am aware of similar data in press. As my coauthors and I suggested, "AIDS reflects and magnifies diseases that are endemic to a particular locality." Atlanta was third in the nation in tuberculosis case rate in 1984,<sup>2</sup>and Guarner et al describe the population served by Grady Memorial Hospital as being an "inner-city, low socioeconomic status, predominantly black" one. Reichman et al<sup>3</sup>showed in 1979 (before the AIDS epidemic) that intravenous drug abuse was a risk factor for tuberculosis beyond race and socioeconomic status; this was confirmed in our series of patients with AIDS, who were from a population of intravenous
Canine mammary neoplasms and progestogens
Authors: L. W. Nelson
Journal: JAMA (1972)

The mixed mammary tumor is a distinct entity in dogs, with only rare reports of similar neoplasms in man. From data now available, megestrol acetate, chlormadinone acetate, and progesterone may have a promotional effect on the occurence of canine mixed mammary tumors. These compounds—progesterone and progesterone derivatives—have marked species difference, with dogs unusually responsive. Species variability in drug metabolism and drug sensitivity and individual specific variation in target organ pathology are all important in the safety evaluation of products for human use. The facts presented herein support the contention that an increased incidence of the progestogen-dependent canine mixed mammary tumor is, in itself, of little relevance in projecting potential tumorigenesis in women.
"SMOOTH" vs. "ROUGH" TYPHOID VACCINES
Journal: JAMA (1934)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
May's Manual of the Diseases of the Eye for Students and General Practitioners.
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Anatomy Lab
Journal: JAMA (1998)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hypokalemic respiratory arrest in diabetic ketoacidosis
Authors: R. I. Dorin
Journal: JAMA (1987)

THE OCCURRENCE of life-threatening hypokalemic hypoventilatory respiratory failure requiring intubation and respiratory support in diabetic ketoacidosis (DKA) is exceedingly rare. In none of the reported cases have serum phosphate levels been assessed within 12 hours of respiratory failure and in only one case have serial arterial blood gas measurements been performed to document hypoventilation.<sup>1</sup>The recent documentation of severe hypophosphatemia as a cause of hypoventilation and the fact that decrements in serum phosphate and serum potassium levels frequently parallel one another in DKA call into question the importance of hypokalemia to the respiratory response in DKA. We report a case of DKA in a young, otherwise healthy man whose treatment was complicated by severe hypokalemia and a hypoventilatory respiratory arrest without severe hypophosphatemia. We further discuss issues relating to the assessment and treatment of the hypokalemic patient with DKA at risk for ventilatory failure. <h3>Report of a Case</h3>
Book Listings
Journal: Annals of Internal Medicine (2002)

Book Listings1 October 2002Book ListingsSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-137-7-200210010-00036 SectionsAboutFull Text ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail CardiologyAlcohol and Heart DiseaseR Watson and AK Myers, eds. 261 pages. Philadelphia: Taylor & Francis; 2002. $80.00. ISBN 0415273471. Order phone 800-821-8312.Beta-Blockers in Heart FailureJ McMurray and MJ Kendall. 108 pages. Philadelphia: Taylor & Francis; 2002. $15.00. ISBN 1853179027. Order phone 800-821-8312.Blackwell's Primary Care Essentials: CardiologyJ Sutherland. 304 pages. Cambridge, MA: Blackwell Science; 2001. $40.00. ISBN 0632044756. Order phone 800-759-6102.Cardiac Arrythmias: Practical Notes on Interpretation and Treatment6th edition. DH Bennett. 340 pages. Boston: Arnold; 2002. $30.00. ISBN 0340807318. Order phone 800-759-6102.Cardiogenic Shock: Diagnosis and TreatmentD Hasdai, PB Berger, A Battler, and DR Holmes Jr, eds. ... Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 October 2002Volume 137, Issue 7Page: B1 ePublished: 1 October 2002 Issue Published: 1 October 2002 Copyright & PermissionsCopyright © 2002 by American College of Physicians. All Rights Reserved.Loading ...
Commentaire de travail de L. Polese et al., pp. 23
Journal: Endoscopy (2008)

See also: Gastrointestinal telangiectasia: a study by EGD, colonoscopy, and capsule endoscopy in 75 patientsEndoscopy 2008; 40(01): 23-29DOI: 10.1055/s-2007-967039
Enhanced Nitric Oxide–Mediated Vascular Relaxation in Radial Artery Compared With Internal Mammary Artery or Saphenous Vein
Authors: Oz M. Shapira, Aiming Xu, Gabriel S. Aldea, Joseph A. Vita, Richard J. Shemin, John F. Keaney
Journal: Circulation (1999)

Background —The superior long-term patency of internal mammary artery coronary bypass grafts compared with venous grafts has been attributed in part to increased endothelium-derived nitric oxide (·NO) production. Interest in the radial artery as an alternative bypass conduit has recently been revived; however, its biological characteristics remain incompletely defined. The purpose of this study was to compare the ·NO-mediated vasomotor properties of the radial artery to those of the internal mammary artery and saphenous vein. Methods and Results —Matched segments of radial artery, internal mammary artery, and saphenous vein (n=24 patients) were examined by use of organ-chamber methodology. Endothelium-dependent and -independent vasomotor responses were assessed by dose-response curves to acetylcholine, N G -nitro- l -arginine methyl ester (L-NAME), 8-bromo-cyclic 3′,5′-guanosine monophosphate (8-bromo-cGMP), and nitroglycerin. Maximum ·NO-mediated radial artery relaxation in response to acetylcholine (86±10%) was significantly greater than internal mammary artery (56±9%) or saphenous vein (11±5%, both P &lt;0.0001). Similarly, acetylcholine-stimulated cGMP accumulation in radial artery (9.1±1.7 pmol/mg protein) was also greater than internal mammary artery (6.2±0.3 pmol/mg protein) or saphenous vein (1.4±0.2 pmol/mg protein, both P &lt;0.05). Estimated basal endothelial ·NO production, assayed as the percent maximum contraction in response to L-NAME, was greater in radial artery (39±5%) than internal mammary artery (23±6%) or saphenous vein (5±2%, both P &lt;0.05). Maximum relaxation of all vessels to nitroglycerin was similar, although the sensitivity of radial artery to nitroglycerin was greater (EC 50 =33±7 nmol/L) than the internal mammary artery (203±32 nmol/L) or saphenous vein (97±12 nmol/L, both P &lt;0.05). Vascular cGMP in response to 0.1 μmol/L nitroglycerin was significantly higher in the radial artery (8.3±1.4 pmol/mg protein) compared with the internal mammary artery (3.5±1.3 pmol/mg protein) or saphenous vein (1.4±0.3 pmol/mg protein, both P &lt;0.0001). Relaxation to 8-bromo-cGMP was identical for all 3 conduits. Conclusions —These data indicate that ·NO-dependent relaxation of radial artery is greater than that of internal mammary artery or saphenous vein. This difference is related to endothelial production of ·NO and/or vessel sensitivity to ·NO. Such favorable physiological characteristics of radial artery could conceivably contribute to improved long-term patency of this conduit compared with saphenous vein.
JAMA 100 Years Ago
Journal: JAMA (1987)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Ethylene Glycol Monomethyl Ether (EGME) and Propylene Glycol Monomethyl Ether (PGME): Inhalation Fertility and Teratogenicity Studies in Rats, Mice and Rabbits
Authors: Thomas R. Hanley, John T. Young, Jacqueline A. John, K. S. Rao
Journal: Environmental Health Perspectives (1984)

A combined dominant lethal-fertility study was conducted in which male and female Sprague-Dawley (CD) rats were exposed to 0, 30, 100 or 300 ppm of ethylene glycol monomethyl ether (EGME) vapor for 6 hr/day, 5 days/week for 13 weeks and then mated to untreated counterparts. Among males, fertility was completely suppressed after exposure to 300 ppm. A partial restoration of reproductive function was evident following 13 weeks of recovery. No treatment-related reproductive effects were observed among males exposed subchronically to 100 ppm, or among females exposed to 300 ppm or below of EGME. Studies to assess the effects of inhaled EGME on embryonal and fetal development were also conducted in Fischer 344 rats, CF-1 mice, and New Zealand White rabbits. Rats and rabbits were exposed to concentrations of 0, 3, 10 or 50 ppm for 6 hr/day on days 6-15 or 6-18 of gestation, respectively. Exposure of rabbits to 50 ppm resulted in significant teratologic effects, an increased resorption rate, and decreased fetal body weight. Slight fetotoxicity in the form of skeletal variations were observed among rats exposed to 50 ppm. Exposure of pregnant mice to 0, 10, or 50 ppm for 6 hr/day on days 6-15 of gestation resulted in slight fetotoxicity at 50 ppm. No significant treatment-related effects were observed at 10 ppm of EGME or below in any of the species tested. Separate groups of pregnant rats and rabbits were exposed to 0, 500, 1500 or 3000 ppm of propylene glycol monomethyl ether (PGME) during organogenesis.(ABSTRACT TRUNCATED AT 250 WORDS)
Recycling
Authors: Edward Volpintesta
Journal: Annals of Internal Medicine (2014)

Letters20 May 2014RecyclingEdward Volpintesta, MDEdward Volpintesta, MDFrom Danbury Hospital, Danbury, Connecticut.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/L14-5010-4 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:I appreciate King's (1) concise criticism of forces that have undermined the integrity, peace of mind, and very soul of medicine. Clearly, masters of business administration have usurped the control of medicine. Like King, I find that “medical home,” “patient-centered care,” and “accountable care organizations” are just buzzwords meant mostly for policymakers to use in their relentless efforts to extend their control over the practice of medicine. And for all the theoretical good that electronic health records may do, they have not made me a more capable physician.However, I was disappointed that King said that he ...Reference1. King JH. Recycling. Ann Intern Med. 2014;160:68. [PMID: 24395465] LinkGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Danbury Hospital, Danbury, Connecticut.Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L14-0113. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoRecycling James H. King Recycling James H. King Recycling Richard Blakely Recycling James H. King Recycling Richard Blakely Recycling James H. King Metrics 20 May 2014Volume 160, Issue 10Page: 738KeywordsDisclosureElectronic medical records ePublished: 20 May 2014 Issue Published: 20 May 2014 CopyrightCopyright © 2014 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...