tbuckley/cabot-search huggingface dataset:
Acute Sensory Responses of Nonsmokers at Very Low Environmental Tobacco Smoke Concentrations in Controlled Laboratory Settings
Authors: Martin H. Junker, Brigitta Danuser, Christian Monn, Theodor Koller
Journal: Environmental Health Perspectives (2001)

The objective of this study was to provide a basis for effectively protecting nonsmokers from acute sensory impacts and for preventing deterioration of indoor air quality caused by environmental tobacco smoke (ETS) emissions. With an olfactory experiment we determined odor detection thresholds (OT) of sidestream ETS (sETS), and with a full-body exposure experiment we investigated sensory symptoms at very low sETS exposure concentrations. OT concentrations for sETS are three and more orders of magnitude lower than ETS concentrations measured in field settings and correspond to a fresh air dilution volume of > 19,000 m(3) per cigarette, over 100 times more than had previously been suggested for acceptable indoor air conditions. Eye and nasal irritations were observed at one order of magnitude lower sETS concentrations than previously reported, corresponding to a fresh air dilution volume of > 3,000 m(3) per cigarette. These findings have great practical implications for defining indoor air quality standards in indoor compartments where ETS emissions occur. Our study strongly supports the implementation and control of smoking policies such as segregating smoking areas from areas where smoking is not permitted or instituting smoking bans in public buildings.
Sulfonamides and Aspergillosis
Authors: Randi V. Rosvoll
Journal: JAMA (1969)

<h3>To the Editor:—</h3> InThe Journal(<b>209</b>:1191, 1969) a case of pulmonary aspergillosis is reported. A number of articles on systemic aspergillosis cite the various types of therapy during the past few years. None has mentioned the use of sulfonamide drugs. The studies and observations, made in the bacteriology laboratory of the New England Baptist Hospital, on a strain of<i>Aspergillus</i>isolated from a case of pulmonary aspergillosis noted that the organism was very sensitive to sulfonamides. A number of strains of<i>Aspergillus</i>were obtained and most of them were found to be sensitive to sulfonamides. We had hoped to test the clinical success of this therapy but have not had any cases of aspergillosis for treatment. We should like to report this experience in the hope that this type of therapy might be found useful. We realize that sensitivities on an agar plate might not reflect in vivo
Suicide
Authors: Leon D. Hankoff
Journal: JAMA (2006)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
CULTIVATION OF RICKETTSIA-LIKE BODIES IN TYPHUS FEVER
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Interdependence of medical and allied health education
Authors: R. J. Atwell
Journal: JAMA (1970)

My first reaction, when asked to speak about the interdependence of medical and allied health education, was that this would be an easy topic. I could simply say that there is precious little. Probably this would be the most provocative approach to the problem. I have given much thought to the existing patterns of education for these two branches of health, and it is obvious that interrelationship could be greatly improved. But the question of how best to achieve this is not so simple. I don't pretend to understand all of the problems, let alone have the solutions. During the past two days, I have been meeting with the Student American Medical Association where the medical students have been addressing themselves to some of these very same problems. This has been a very interesting experience. Let's begin by looking briefly at existing educational processes in the allied health professions. If
AMAGRAMS
Journal: JAMA (1974)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Marijuana. Its health hazards and therapeutic potentials. Council on Scientific Affairs
Journal: JAMA (1981)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Analysis of small RNA molecules in childhood atopic dermatitis reveals a role for miR‐451a
Journal: British Journal of Dermatology (2021)

Atopic dermatitis (also known as atopic eczema) is the most common persistent inflammatory disease of early childhood, affecting more than 20% of children in developed countries.It causes extremely itchy skin and has a very significant impact on the quality of life of affected children and their families.It is caused by a combination of environmental factors and changes in the skin and immune system; however, the exact mechanisms behind the development of the disease are not fully understood.MicroRNAs are small pieces of genetic material that play a crucial role in a vast number of biological processes (ways things work within the body) because of their ability to alter the activity of the genes they target.In recent years there has been great interest in the potential of microRNAs as diagnostic and prognostic biomarkers (indicators of a biological process), as well as predictors of drug response, meaning how well a drug works for a patient.However, little is known about microRNAs in atopic dermatitis in children.The major goal of this work, based at the National Children's Research Centre, Dublin, Ireland, was to identify unique disease-related microRNAs that might allow early diagnosis of atopic dermatitis in children.Using state-of-the-art genetic techniques, we investigated levels of microRNAs in different components of blood taken from children with atopic dermatitis and compared them with the levels in healthy children during their first year of life.We identified unique microRNAs associated with atopic dermatitis in children.We showed that a specific microRNA, named microRNA-451a, may serve as an efficient tool to allow diagnosis of atopic dermatitis in children .We identified a unique miRNA signature in infants with atopic dermatitis.MicroR-451a may serve as a promising indicator, easily obtainable from a blood sample, to diagnose the disease and may help to identify babies at risk at an earlier stage, allowing for intervention very early in life.
MUSIC AS A THERAPEUTIC MODALITY
Journal: JAMA (1953)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Th2 cell hyporesponsiveness during chronic murine schistosomiasis is cell intrinsic and linked to GRAIL expression
Authors: Justin J. Taylor, Connie M. Krawczyk, Markus Mohrs, Edward J. Pearce
Journal: Journal of Clinical Investigation (2009)

During the preparation of the manuscript, the mice in Figure 2 were incorrectly identified as having been infected with S. mansoni.The correct legend for Figure 2A appears below.(A) Mice received 1 or more egg injections.Repeat egg injections were 5 d apart, such that mice for the 20-d time point had received 4 injections prior to sacrifice.At 5, 10, 15, and 20 d after the first immunization, CD4 + T cells from draining popliteal LNs were analyzed ex vivo for the expression of IL-4/GFP by flow cytometry.Numbers within plots indicate mean ± SD percent of CD4 + cells that were IL-4/GFP + (3 mice per group).The JCI regrets the error.
The trauma score as a triage tool
Authors: Edward Belongia
Journal: JAMA (1987)

<h3>To the Editor.—</h3> The study by Morris et al<sup>1</sup>on correlation of the field Trauma Score (TS<sub>1</sub>) with the Injury Severity Score (ISS) has important implications for appropriate triage of patients to regional trauma centers. These authors are correct in pointing out that it is most important to minimize false-negative assessments despite the unavoidable increase in false-positives. The addition of the diagnosis of penetrating torso trauma as an absolute criterion for transport to a trauma center would have decreased the number of false-negatives from 66 to 55 and increased the false-positives from 107 to 206 (rather than 260, as stated by the authors). This would have had the effect of increasing sensitivity from 63.3% to 69.0% and decreasing specificity from 88.4% to 77.6%. The postassessment probability of severe trauma (ISS≥20) following a negative field assessment (TS<sub>1</sub>&gt;14) is given by the ratio of false-negatives to all negatives.<sup>2</sup>
Campylobacter enteritis associated with a healthy cat
Authors: M. J. Blaser
Journal: JAMA (1982)

IN THE short time since<i>Campylobacter jejuni</i>has become recognized as a significant enteric pathogen of humans, information on the epidemiology of infection has been increasing rapidly.<sup>1</sup>Although direct contact with infected animals or consumption of contaminated water or foods of animal origin are generally suspected as being the important modes of transmission, in only the minority of cases can this be documented. Recent work has implicated contact with infected household pets as one avenue of transmission.<sup>2-4</sup>The pets involved in such cases were puppies and kittens with diarrhea who were shedding<i>C jejuni</i>. We now report a case of<i>Campylobacter</i>enteritis that occurred in association with infection in an apparently healthy adult cat. <h3>Report of a Case</h3> On Oct 15, 1980, nausea, vomiting, and severe abdominal cramps developed in a 23-year-old woman, and she began having up to five bloody bowel movements per day. On Oct 19,
Chronic expanding hematomas. A clinicopathologic entity
Authors: J. D. Reid
Journal: JAMA (1980)

Chronic expanding hematomas occur in many locations, often simulating neoplasms. All have the same structure with a central mass of blood, a wall of granulation tissue, and dense, fibrous tissue at the periphery. The self-perpetuating expanding nature of the lesion appears to be due to the irritant effects of blood and its breakdown products, causing repeated exudation or bleeding from capillaries in the granulation tissue. (<i>JAMA</i>244:2441-2442, 1980)
A Course of Lectures on Surgery: Delivered in the Medical School of Cambridge
Authors: G. M. Humphry
Journal: BMJ (1849)

Effects of Inflammation; the Order in which they occsur varies according to the Vitality and Peculiarity of the Tissue affected,and the Peculiarity ofthe Inflammation: E,ffused Serum generally disappears with the Inflam- mation; occasionally ispersistent; sometimes is the only Symptom, as in Hydrocele, Hydrothorax, Hydrops Articuli; Treatment: Effusion of Lymph, its Organization; rarely becomes organized on the Surface of Skin or Mucous Membrane; the Structure into which it is converted; shows Signs of imperfect Assimilation of Fibrin by its Contraction, which, as well as the Disposition to contract when stretched, ceases after a Time; Strictures; Cicatrices; Contractions of Joints; the Force of Contraction proportionate to the Force of Organization of the Fibrin, from which the new Structure is formed;false Membranes liable to same Diseases as other Parts,-to calcareous Degeneration; undtego variou& other Changes, according to the Move.ments and assimilative Influences of surrounding Parts-in Bursae, Joints, serous Cavities; Melon- sed-like bodies; loose Cartilages.Insidious Lymph.ffsa*ions; Treatment by Mercury, Stimulants, Pressure, Bougies; their Mode of Action; Excision.The injurious effects of inflammation upon the organ in which it is seated consist, first, in the effusion of new products, serum, lympb, and pus, ihtO the interstices of its" substance; and, secondly, in the alteration and destruction of its texture by atrophy, softening, inter- stial absorption, ulceration, and mortification.In the ordrnary course of tbings these changes take place netiy in the order above enumerated, the efrusion of serum being the attendant on the mildest, and mortifi- catbn'theresult of the severest, forms of the disease.This order is, however, liable to be interrupted by ndlmerous causis, such as variations in the strength of tlie pstient, and the vital energy of the part affected.I have before mentioned that in old and feeble persons a slight amount of inflammation is quickly followed by ulteiition and mortification.The vitality of the textuies is witb difficulty maintained in such persons No. 6, March 21, 1849.under ordinary circumstances, and gives way altogetber under the disturbing agency of inflammation.Compare the inflammation of the healtby and robust man with that in the lower extremities of the old person, where the nutritive and reparative forces are failing, and the circulation is impaired by the diseased condition of the great arterial trunks.In the former the inflammation, acute and painful in its progress, is attended by the formation of lymph and pus, uleeration occurs only to a sufficient extent to open the abscess, the conteats of which are well elaborated and quiickly discharged, granu- lations follow, and cicatrization takes place without much loss of time; whereas, in the extremities of the dged and infirm, the inflammation, consequent probably
Treatment of uncontrolled seizure activity with diazepam
Authors: G. T. Sawyer
Journal: JAMA (1968)

Diazepam (Valium) was administered intravenously to 26 patients with varying degrees of prolonged, uncontrolled seizure activity. The seizures were terminated rapidly in 16 cases and less satisfactorily in 10. Patients with acute, rapidly progressive cerebral disorders were most resistant to treatment. Concurrent electroencephalographic monitoring demonstrated in 13 of 18 tracings that diazepam quickly suppressed the spikes. Intramuscularly administered follow-up doses of diazepam, used with other anticonvulsants, assisted in the maintenance of control. Intravenously administered diazepam is an excellent short-term anticonvulsant with relatively few adverse reactions. It is often effective after large doses of other parenterally administered anticonvulsants have failed to establish seizure control.
Primary care physicians' response to domestic violence. Opening Pandora's box
Authors: N. K. Sugg
Journal: JAMA (1992)

<h3>Objective.</h3> —To explore primary care physicians' experiences with domestic violence victims to determine the barriers to problem recognition and intervention in the primary care setting. <h3>Design.</h3> —Ethnography, a qualitative research method involving the use of open-ended, semistructured interviews. <h3>Setting.</h3> —An urban health maintenance organization serving a predominantly white, middle-income population. <h3>Participants.</h3> —Thirty-eight physicians, predominantly family practitioners (89%), were interviewed. <h3>Results.</h3> —Analysis of the interviews revealed that physicians found exploring domestic violence in the clinical setting analogous to "opening Pandora's box." Their issues include lack of comfort, fear of offending, powerlessness, loss of control, and time constraints. <h3>Conclusion.</h3> —This study revealed several barriers that physicians perceived as preventing them from comfortably intervening with domestic violence victims. These issues need to be addressed in training programs. Further studies should be done to assess generalizability of these findings to other groups of physicians. (<i>JAMA</i>. 1992;267:3157-3160)
Les stupéfiants.
Journal: JAMA (1927)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Correction
Journal: BMJ (1926)

made in the eighties.In 1898 Dr. Sechehaye of Geneva, wlhite experimenting with x rays, discovered, a yellow substance which was particularly opaque, and with it he prepared a skin cream, which is stated to be an efficient prophylactic against Alpine sunburn and also sunstroke.It is dispensed in con- venient collapsible tubes under the title of " Pomade du Dr. Sechehaye " by the Pharmacie Hausser, 10, Bourg-de-Four, Geneva, price 2.50 (Swiss) francs.With regard to treatment, Dr. Wilson says that hot-water sponging, followed by a bland powder (" pasma " is said to be one of the best), and then by an application of vaseline, when the skin becomes dry, will relieve the pain and cure the dermatitis within two or three days." STATIC ALBUMINURIA."
Boxing
Authors: R. K. Naviaux
Journal: JAMA (1983)

<h3>To the Editor.—</h3> Ross and colleagues have written a timely article on the neuropathological consequences associated with boxing. Their conclusions are, however, weakened by certain methodological difficulties. Although the authors emphasize that the CT scores they report are adjusted for normal, age-dependent changes in sulcal and ventricular size, multiple regression analysis of their data reveals that fighter age remainsthe most significant correlate of observed CT scan abnormalities (<i>R</i>=.409,<i>P</i>&lt;.02). In addition, multiple regression analysis fails to show a significant correlation of CT scores with the number of bouts fought (<i>R</i>=.239,<i>P</i>&gt;.05). Statistical data are summarized in Tables 1 and 2. While these results conflict with the conclusions drawn by the authors, they point out an interesting possibility. Could the normal CT scan changes that occur with age be accelerated in some way by boxing? By including age-matched, normal controls and reporting the CT scan changes