tbuckley/cabot-search huggingface dataset:
Zinc and Deficiencies of Taste and Smell
Journal: JAMA (1994)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Broad Genomic Testing in NSCLC: No Survival Benefit?
Journal: Cancer Discovery (2018)

Abstract A retrospective analysis of patients with advanced non–small cell lung cancer treated in community clinics found no benefit of broad genomic testing over routine testing for abnormalities in EGFR and ALK. However, the reason may have more to do with patients not receiving targeted therapy than with any inherent flaws in genomics-guided precision medicine.
Wrongful Life
Authors: Susan M. Schmidt
Journal: JAMA (1983)

DURING the last decade, the number and theories of birth-related legal claims have increased. This increase can be partially attributed to the availability of medical information and genetic and prenatal testing. Prenatal diagnosis through amniocentesis and related procedures during the first trimester of pregnancy has become common, and contraceptive and sterilization techniques have become more readily available. Further,<i>Roe v Wade</i>, 410 US 113 (1973), placed the decision to terminate pregnancy during the first trimester within the woman's constitutional right of privacy. Of all the birth-related legal theories, wrongful life, an action filed on behalf of the infant born with a genetic or other congenital birth defect, has met with the most disapproval. Wrongful life is the child's cause of action. The child alleges that the physician failed to inform and advise the parents adequately concerning foreseeable fetal risks from genetic or other congenital defects. Because of this failure to
Comparison of the prediction by 27 different factors of coronary heart disease and death in men and women of the Scottish heart health study: cohort study
Journal: BMJ (1998)

Objectives: To determine the effectiveness and acceptability of general practitioners'opportunistic antismoking interventions by examining detailed accounts of smokers' experiences of these.Design: Qualitative semistructured interview study.Setting: South Wales.Subjects: 42 participants in the Welsh smoking intervention study were asked about initial smoking, attempts to quit, thoughts about future smoking, past experiences with the health services, and the most appropriate way for health services to help them and other smokers.Results: Main emerging themes were that subjects already made their own evaluations about smoking, did not believe doctors' words could influence their smoking, believed that quitting was down to the individual, and felt that doctors who took the opportunity to talk about smoking should focus on the individual patient.Smokers anticipated that they would be given antismoking advice by doctors when attending for health care; they reacted by shrugging this off, feeling guilty, or becoming annoyed.These reactions affected the help seeking behaviour of some respondents.Smokers were categorised as "contrary," "matter of fact," and "self blaming," depending on their reported reaction to antismoking advice.Conclusions: Doctor-patient relationships can be damaged if doctors routinely advise all smokers to quit.Where doctors intervene, a patient centred approach-one that considers how individual patients view themselves as smokers and how they are likely to react to different styles of intervention-is the most acceptable.
Two Approaches
Authors: Thomas E. Finucane
Journal: Annals of Internal Medicine (1990)

Ad Libitum15 October 1990Two ApproachesThomas E. Finucane, MDThomas E. Finucane, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-113-8-641_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptI. InterceptSkiing alone on a bright quiet hillI once crossed a rabbit's tracksAnd followed themDown on a powdered meadow.Confident and direct they sped,Straight 'til the wild final flurryOf criss-cross and cut-backThen they endedOut on the open snow.I pictured the hawk who had taken him—Her unerring, converging descent.II. AsymptoteI followed a miner downIn medicine clinicPhlegmatic, he'd stuck by his LuckiesBut last March mentioned coughing blood.He entered then the silent LandOf Scan and ProtocolOf Chemo and Crude Survival.No hawk for him now... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Baltimore, Maryland PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 15 October 1990Volume 113, Issue 8Page: 641-641KeywordsBloodCoughingRabbits ePublished: 1 December 2008 Issue Published: 15 October 1990 Copyright & Permissions© 1990 American College of PhysiciansPDF downloadLoading ...
Pediatric Medicine
Authors: Basil J. Zitelli
Journal: JAMA (1994)

<i>Pediatric Medicine</i>by Drs Mary Ellen Avery and Lewis First represents another entry into the arena of major pediatric textbooks. Avery and First bring to their text the perspective of pediatric attending physicians at Children's Hospital in Boston, in a traditional, organ-based approach. What is unusual compared with better-known texts is the inclusion of sections on "New Developments," "Controversies," and "Case Illustrations with Questions and Comments." "New Developments" emphasizes advances in diagnostic techniques and therapies. "Controversies" notes gray areas of understanding or even tenets often taken as truth but unproven. "Case Illustrations" are brief and representative, often followed by common questions and discussions of particular disorders. The second edition emphasizes the value of case illustrations as a learning tool. In addition, basic science sections have been expanded but remain succinct. When appropriate, simplified metabolic pathways are included to aid understanding of basic pathophysiology. Discussions of pharmacology are integrated into each
Applied Psychology for Nurses.
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Obstetric Memoranda
Journal: BMJ (1884)

form of obstruction, but to general uterine congestion, it will follow, as a matter of course, that tunnelling or other forcible dilatation is an unnecessarily radical and severe method of cure.We may hope that a course of counterirritation over the sacrum, by blisters or tincture of iodine, will reduce the congestion and prevent the recurrence of the pain.Other methods of relieving or preventing the pain will also suggest themselves, such as glycerine or alcohol-plugs, leeches, scarifi-Miss E., aged 33, came under my observation in the beginning of June last.Sle told me that she was a chronic invalid ; that for years she had been relegated to the list of incurables; that she was a pronounced martyr to chronic rheumatism, gouty rheumatism, etc.I was merely asked to treat her for a little intercurrent affection.But
Cost effectiveness of magnetic resonance imaging.
Authors: L. J. Abernethy
Journal: BMJ (1992)

severity of health problems and the variety of It seems inappropriate for conclusions about the resonance imaging (produced since our paper was options for care and care settings.impact of radiological investigations on patients' submitted) concludes that further work is needed Secondly, concern about the use of QALYs still quality of life to be drawn from an audit of this to measure the effects of magnetic resonance focuses on doubts about their adequacy as measures nature.imaging on patients' quality of life "but that such of health gain' and on the technical validity of L JABERNETHY data may be difficult to obtain."' Our experience comparisons of costs per QALY.' Though these Department of Radiology, supports-this.problems may be overcome, we believe that the Royal Children's Hosspsital, A K SZCZEPURA authors' conclusions are mistaken, even when Meborne
Chemotherapy for advanced male breast cancer
Authors: H. Y. Yap
Journal: JAMA (1980)

An analysis of 29 chemotherapeutic trials in 18 male patients with advanced breast cancer disclosed an overall response rate of 44%. Most of these chemotherapeutic trials consisted of single-agent regimens, namely, fluorouracil, methotrexate, thiotepa, cyclophosphamide, and melphalan. Our data suggest that responsiveness of advanced male breast cancer to systemic chemotherapeutic agents is the same as that reported for advanced female breast cancer. (<i>JAMA</i>243:1739-1741, 1980)
Regulations and legislation concerning abortus research
Authors: M. H. Dykes
Journal: JAMA (1974)

FOUR physicians involved in abortus research have recently been indicted in Boston under the provisions of a Violation of Sepulture law aimed at restricting grave robbing.<sup>1,2</sup>The law was passed in 1814 and prohibits the unauthorized removal and conveying away of human bodies or the remains thereof. Whatever the disposition of these cases, the fact that the National Institutes of Health are formulating regulations<sup>3</sup>and the Congress is preparing legislation (HR7724)<sup>2</sup>on the subject of human experimentation indicates that general commentary on the issue is appropriate. The research from which the indictments stem was reported in the<i>New England Journal of Medicine</i>of June 7, 1973, and was concerned with solving the problem posed by the need to prescribe antibiotics "for pregnant women allergic to penicillin."<sup>4</sup>In order to perform the necessary studies, the investigators obtained the dead abortuses of a group of pregnant women who
Anencephalic organ donor program suspended; Loma Linda report expected to detail findings
Authors: M. F. Goldsmith
Journal: JAMA (1988)

TAKING HEALTHY HEARTS from doomed babies born without a brain and giving them to brain-intact infants who had life-threatening congenital heart defects seemed like a good idea to the transplant team at Loma Linda (Calif) University Medical Center nine months ago. Suspension of the research protocol was announced last month after Leonard Bailey, MD, of the Department of Cardiothoracic Surgery and his colleagues failed for various reasons to perform even one such procedure, despite having a dozen anencephalic infants flown by Learjet to Loma Linda from around the country. <h3>Final Decision Pending</h3> Now the institution is rethinking its approach and is issuing a report said to contain "a wealth of information obtained from the study." A final decision on the future of the program will be made after all the information is evaluated. According to Dick Schaefer, Loma Linda's director of community relations, the medical center remained committed late last
HIGH BLOOD PRESSURE STASIS
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
DISCUSSION ON PAPER OF DR. S. SOLIS-COHEN, "THE TREATMENT OF EXOPHTHALMIC GOITER AND OTHER VASOMOTOR ATAXIAS."
Journal: JAMA (1897)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
ANAPHYLACTIC SHOCK BY AZODYES. II
Authors: K. Landsteiner, J. van der Scheer
Journal: The Journal of Experimental Medicine (1938)

From the experiments presented, it follows that the specific precipitation and the production of anaphylactic shock with certain azodyes, as described previously, is due to these substances themselves and is not dependent upon formation of azoproteins by interaction of the dyes with proteins in the test tube or the animal body. Besides these, some other azodyes which in our tests did not give precipitation with corresponding immune sera were also found, in very small quantities, to induce anaphylactic contraction of the uterus of sensitized guinea pigs.
Perioral dermatitis
Authors: I. B. Sneddon
Journal: British Journal of Dermatology (1980)

Journal Article Perioral dermatitis Get access I. B. Sneddon I. B. Sneddon I Belsize Road, Sheffield SIo 3TN Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 102, Issue 2, 1 February 1980, Pages 239–240, https://doi.org/10.1111/j.1365-2133.1980.tb05701.x Published: 01 February 1980
VITAMIN K AND CHOLEMIC BLEEDING
Journal: JAMA (1941)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Three Testicles
Authors: W. J. O'Donovan
Journal: BMJ (1953)

Activation-induced cytidine deaminase (AID) initiates a process generating DNA mutations and breaks in germinal center (GC) B cells that are necessary for somatic hypermutation and class-switch recombination. GC B cells can “tolerate” DNA damage while rapidly proliferating because of partial suppression of the DNA damage response by BCL6. In this study, we develop a model to study the response of mouse GC B cells to endogenous DNA damage. We show that the base excision repair protein apurinic/apyrimidinic endonuclease (APE) 2 protects activated B cells from oxidative damage in vitro. APE2-deficient mice have smaller GCs and reduced Ab responses compared with wild-type mice. DNA double-strand breaks are increased in the rapidly dividing GC centroblasts of APE2-deficient mice, which activate a p53-independent cell cycle checkpoint and a p53-dependent apoptotic response. Proliferative and/or oxidative damage and AID-dependent damage are additive stresses that correlate inversely with GC size in wild-type, AID-, and APE2-deficient mice. Excessive double-strand breaks lead to decreased expression of BCL6, which would enable DNA repair pathways but limit GC cell numbers. These results describe a nonredundant role for APE2 in the protection of GC cells from AID-independent damage, and although GC cells uniquely tolerate DNA damage, we find that the DNA damage response can still regulate GC size through pathways that involve p53 and BCL6.
Intravenous glucagon.
Authors: W I Shedden
Journal: BMJ (1971)

gases, lactate metabolism, and acid-base balance during and after exercise, and some of the results are to be published shortly.Basically we found that none of these factors could explain the origin of exercise-induced asthma or the difference with different forms of exercise.Likewise, we have studied lung volumes and mechanical properties and found that they reflect rather than cause the asthma.Finally, we would like to repeat our earlier suggestion that the mechanism of exercise-induced asthma and the difference between the severe constriction due to running compared with the virtual absence during swimming may reflect neuro- muscular differences in the types of exercise.
AUTOMATED CLASSIFICATION OF GASTRIC NEOPLASMS IN ENDOSCOPIC IMAGES USING A CONVOLUTIONAL NEURAL NETWORK
Authors: CS Bang, BJ Cho, GH Baik
Journal: Endoscopy (2020)

Aims Visual inspection, lesion detection, and differentiation between malignant and benign features are key aspects of an endoscopist´s role. The use of machine learning for the recognition and differentiation of images has been increasingly adopted in clinical practice. This study aimed to establish convolutional neural network (CNN) models to automatically classify gastric neoplasms based on endoscopic images.
Clinical Science
Journal: JAMA (1962)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Sharing decisions is uncomfortable for GP registrars
Journal: BMJ (1999)

Decision aids do improve patients' decision makingTrials of aids to help patients consider the benefits and harms of medical treatments show that they improve patients' knowledge, comfort, and participation in decision making without increasing anxiety.The systematic review by O'Connor et al (p 731) also found that decision aids had little effect on satisfaction and an inconsistent effect on patients' decisions.The trials of decision aids focused on hormone therapy, circumcision, screening for cancer and genetic disorders, and treatments for prostate cancer, breast cancer, and heart disease.The results consistently showed that decision aids were better than usual practice.
Nonlinear Exposure-Outcome Associations and Public Health Policy
Authors: Amit Kiran, Nathalie Conrad, Kazem Rahimi
Journal: JAMA (2016)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal