tbuckley/cabot-search huggingface dataset:
DERMOID CYSTS AND TERATOMAS OF THE ANTERIOR MEDIASTINUM.
Journal: JAMA (1903)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Phorbol Myristate Acetate and Catechol as Skin Cocarcinogens in SENCAR Mice
Authors: Benjamin L. Van Duuren, Susan Melchionne, Irving Seidman
Journal: Environmental Health Perspectives (1986)

This poor breeding performance was alleviated by cross- breeding male STS mice with female Charles River CD- 1 mice.The details and history of the susceptible mice thus developed were recently described (6).These mice, originally maintained at the Oak Ridge National Lab- oratory, have since than been named SENCAR mice.
Triazine Herbicide Exposure and Breast Cancer Incidence: An Ecologic Study of Kentucky Counties
Authors: Michele A. Kettles, Steven R. Browning, Timothy Scott Prince, Sanford W. Horstman
Journal: Environmental Health Perspectives (1997)

The incidence of breast cancer in the United States has steadily increased for the past three decades. Exposure to excess estrogen, in both natural and synthetic forms, has been implicated as a risk factor for the development of this disease. Considerable interest has been focused on organochlorines, such as the triazine herbicides, and their possible role in the initiation or promotion of human breast cancer. To explore this relationship, an ecologic study of Kentucky counties was designed. Exposure to triazines was estimated by use of water contamination data, corn crop production, and pesticide use data. A summary index of triazine herbicide exposure was developed to classify counties into low, medium, or high exposure levels. Data on county breast cancer rates were obtained from the state registry. A Poisson regression analysis was performed, controlling for age, race, age at first live birth, income, and level of education. Results revealed a statistically significant increase in breast cancer risk with medium and high levels of triazine exposure [odds ratio (OR) = 1.14,p<0.0001 and OR = 1.2, p<0.0001, respectively]. The results suggest a relationship between exposure to triazine herbicides and increased breast cancer risk, but conclusions concerning causality cannot be drawn, due to the limitations inherent in ecologic study design.
Behavioral Observations in Parents Anticipating Death of a Child
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Tuberculosis in dialyzed patients
Authors: R. P. Pradhan
Journal: JAMA (1974)

Five cases of active tuberculosis developed among 136 patients maintained on dialysis for an average period of 1.4 years each. This experience suggests that patients on maintenance dialysis have a greater chance of contracting tuberculous infection. The diagnosis of tuberculosis was difficult because the features of this disease mimicked findings in uremia, and the skin test with purified protein derivative proved unreliable. An awareness of the increased susceptibility of dialysis patients to tuberculosis should lead to the prompt institution of therapy and to the lessening of hazards to other patients and staff. (<i>JAMA</i>229:798-800, 1974)
LEUKOCYTIC SECRETIONS
Journal: JAMA (1923)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
PWE-091 Diagnostic yield in equivocal barium enemas: experience from a UK district general hospital
Authors: S Isse, B Krishnan, A Sarwar, J Subhani
Journal: Gut (2010)

<h3>Introduction</h3> Barium enema (BE) study is known to have a lower sensitivity 1 and specificity than colonoscopy but is often used in less fit patients or those with a lower risk of significant disease. A follow on colonoscopy is required either for therapy (ie, removal of a polyp) or clarification of “equivocal” radiological findings. The very anatomy (eg, marked diverticular disease) that leads to an equivocal BE may make the colonoscopy difficult or even dangerous. Further in anecdotal clinical practice few of these “equivocal” BE resulted in a proven pathology. The study assessed the yield of lower gastrointestinal endoscopy (LGE) used to clarify equivocal BE over a 12-month period at our institution. <h3>Methods</h3> The list of all patients who had BE during a 12-month period was obtained from the radiology database. This was matched to patients who had a LGE in a 14-month period from the same start point. The extended period allowed for delays in arranging the LGE. Patients who had a LGE after the BE and whose indications included “equivocal” BE were identified. Their radiology and endoscopic reports were assessed for indications and findings. <h3>Results</h3> 1381 BE were performed, and 2559 LGE. 139 patients in total were identified who had LGE following a BE. 44 of these patients had LGE due to an equivocal BE. Of these 44 patients two had no clinical indication on retrospective case review. A third (14/44) of the patients were over 70 years old. Of the 42 patients,41 had normal findings at the area of suspicion (98%). One patient (2%) had a benign stricture confirmed on LGE but did not require any intervention. Furthermore, no cancers were detected, however, 4/44 (9.1%) had polyps not identified on the BE. In the remaining 95 patients who had LGE following a BE for other indications, primarily therapy or biopsies;polyps were identified in 34% and cancers in 13%. <h3>Conclusion</h3> Very few BE required clarification of equivocal findings (42/1381) 3.0%, furthermore, definite abnormalities at BE had a high yield at subsequent LGE. Although this study was not designed to primarily assess the efficacy of BE it appears a useful investigation. Equivocal results on BE do not seem to be related to the suspicion of a lesion as much as a comment on the technical limitations of the study. Clinicians however seem to feel an equivocal result must require clarification. We would urge a different paradigm with review of the case and radiology prior to LGE. This may result in a reduction in these unnecessary procedures often in patients known to be at the greatest risk of complications (ie, over 70-year-olds).
银屑病患者发生过敏性接触性皮炎的情况
Authors: A. Claßen, T. Buhl, S. Schubert, M. Worm, A. Bauer, J. Geier, S. Molin
Journal: British Journal of Dermatology (2019)

近期研究表明,患有银屑病这种皮肤病的人发生接触性皮炎的风险较低,接触性皮炎是在皮肤接触某种刺激物(刺激性接触性皮炎)或过敏原(过敏性接触性皮炎,或称 ACD)后作出的湿疹样反应。本研究专门调查了 ACD 的发病率,接受贴片试验的银屑病患者有 2387 人,相比之下,接受贴片试验的非银屑病人群为 161981 人。贴片试验用来确定哪种潜在过敏原引起某人发生皮肤反应。总的来说,25.2% 的银屑病患者和 38.9% 的非银屑病者对贴片试验使用的过敏原至少发生过一次反应。这些发现表明,银屑病患者发生 ACD 的总体风险显著更低。综上所述,银屑病和接触性皮炎都涉及机体免疫系统的复杂过程,因此在两者同时出现时,很难了解体内具体发生了哪些变化。本研究有助于加深我们对这一主题的认识。
Chronic fatigue in primary care. Prevalence, patient characteristics, and outcome
Authors: K. Kroenke
Journal: JAMA (1988)

Although fatigue is one of the most common complaints in ambulatory care, research has been minimal. Of the 1159 consecutive patients surveyed in two adult primary-care clinics, 276 (24%) indicated that fatigue was a major problem. Fatigue was more prevalent in women than in men (28% vs 19%). Extensive clinical, laboratory, psychometric, and functional data were gathered for 102 fatigued patients and 26 controls. Laboratory testing was not useful in detecting unsuspected medical conditions or in determining the cause of fatigue. Depression or somatic anxiety or both were suggested by screening psychometric instruments in 82 fatigued patients (80%) compared with three controls (12%). Global dysfunction was marked, as reported by patients on the Sickness Impact Profile. The mean score on the Sickness Impact Profile of 11.3 for fatigued patients is similar to that reported for patients with major medical illnesses. After one year of follow-up, only 29 fatigued patients (28%) had improved. The high prevalence, persistence, and functional consequences of fatigue mandate a search for effective therapy. (<i>JAMA</i>1988;260:929-934)
Behçet's Disease
Authors: Tsuyoshi Sakane, Mitsuhiro Takeno, Noboru Suzuki, Goro Inaba
Journal: New England Journal of Medicine (1999)

BehÇet's disease is an inflammatory disorder of unknown cause, characterized by recurrent oral aphthous ulcers, genital ulcers, uveitis, and skin lesions.1,2 All these common manifestations are self-limiting except for the ocular attacks. Repeated attacks of uveitis can cause blindness.13 Behçet's disease is not a chronic, persistent inflammatory disease, but rather one consisting of recurrent attacks of acute inflammation. Involvement of the gastrointestinal tract, central nervous system, and large vessels is less frequent (Table 1), although it can be life-threatening.1,2,46 Susceptibility to Behçet's disease is strongly associated with the presence of the HLA-B51 allele.7,8 Environmental . . .
Systematic reviews of evaluations of diagnostic and screening tests
Journal: BMJ (2001)

Practitioners were asked to give details of any adverse events they considered to be "significant," including any event that was "unusual, novel, dangerous, significantly inconvenient, or requiring further information."There were no reports of serious adverse events, defined as events requiring hospital admission, leading to permanent disability, or resulting in death (95% confidence interval 0 to 1.1 per 10 000 treatments).Practitioners did, however, report 43 minor adverse events, a rate of 1.3 (0.9 to 1.7) per 1000 treatments.The most common events were severe nausea and fainting (table).Three avoidable events-two patients had needles left in, and one patient had moxibustion burns to the skin-were caused by practitioners' errors.Participating practitioners recorded 10 920 mild transient reactions occurring in 5136 treatments, 15% (14.6% to 15.3%) of the 34 407 total.Some local reactions at the site of needling were reported-mild bruising in 587 (1.7%) cases, pain in 422 (1.2%) cases, and bleeding in 126 (0.4%) cases.Patients experienced an aggravation of existing symptoms after 966 (2.8%) treatments, 830 (86%) of which were followed by an improvement, possibly indicating a positive "healing crisis."The most commonly reported mild transient reactions were "feeling relaxed" in 4098 (11.9%) cases and "feeling energised" in 2267 (6.6%) cases, symptoms that often indicate an encouraging response to treatment. 3
Local Penicillin for Ophthalmia Neonatorum
Authors: A. Sorsby, E. Hoffa
Journal: BMJ (1945)

MEDICAL JOURKNA L slow improvement in jaundice and urine.Of the fatal cases, 1 doubt whether any treatment would have saved the two who died of suppression of urine (one treated, one not treated); the third case was not thought severe enough to need penicillin, and this patient died of auricular flutter on the 21st day: this should have been averted if there had been a specific treatment.Lieut.-Col.L. H. Howells and Major R. R. Hughes made an intensive study of seven cases, six of which they treated with penicillin.Their conclusions were as follows:1. Penicillin in adequate doses appeared to shorten the general
Addiction
Journal: JAMA (2002)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
SALMONELLA ARTHRITIS
Journal: JAMA (1960)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Attachment
Authors: Samuel Friedman
Journal: JAMA (1969)

In this first volume of a work entitledAttachment and Loss, Bowlby reviews material on the attachment behavior of infants and young children to the mother figure. He casts doubt on the previous concept of this phenomenon as a mechanism designed essentially to obtain nourishment. For example, young monkeys exhibit typical attachment behavior to a nonfeeding cloth mother model in preference to a feeding wire model. Bowlby concludes that this behavior represents a protective mechanism from predators. Most infants reared in their own homes show attachment behavior by 6 months of age. However, babies in institutions usually fail to do this; nevertheless, if later returned or assigned to a private home and an individual mother figure, they ultimately develop this characteristic reaction. Bowlby repeatedly stresses the importance of interplay and social stimulation between infant and mother. Infants beyond 6 months of age invariably react adversely to a shift in the
Pneumothorax following induction of anesthesia
Authors: M. S. Christian
Journal: JAMA (1969)

A 43-year-old man with chronic alcoholism was admitted to the hospital, subsequent to the destruction of his room by fire. He had sustained second- and third-degree burns which were estimated to involve 25% of his body surface area. The injuries involved his back, left arm, legs, and minor burns about the face. Initial hospital management was difficult, due to failure of cooperation and the development of delirium tremens. He remained febrile with a temperature of 100 to 102 F (37.8 to 38.9 C), and tachycardia was noted. Chest roentgenograms (Fig 1), electrocardiogram, serum electrolyte concentration, and hemoglobin level were within normal limits. On the 14th hospital day, the patient was brought to the operating room for debridement of the burns on his left arm and placement of a splint to correct incipient contractures. Because of the probability of respiratory tract injury, as reflected by voice loss, a regional anesthetic technique
Heparin necrosis. An anticoagulation syndrome
Authors: J. C. Hall
Journal: JAMA (1980)

Lesions indistinguishable from coumarin necrosis developed in three patients who were given heparin sodium subcutaneously. Two of the patients had received only heparin while another had also received coumarin. Heparin necrosis should be added to the list of complications of anticoagulation therapy. (<i>JAMA</i>244:1831-1832, 1980)
Book Review Les Acquisitions Nouvelles de l'Endocrinologie . By R. Rivoire. Masson et Cie, Editeurs, Paris, 1932. Price 26 fr. Atlas der klinischen Elektrokardiographie mit Anleitungen zur Differentialdiagnose . By Wilhelm Dressler. 134 illustrations and 50 plates. Urban and Schwarzenberg, Berlin and Vienna, 1933. A Text-Book of Neuropathology . By Arthur Weil, M.D. Lea &amp; Febiger, Phila., 1933. 335 Pages. Price $5.00.
Journal: New England Journal of Medicine (1933)
Ambulatory Assessment
Authors: Timothy J. Trull, Ulrich Ebner-Priemer
Journal: Annual Review of Clinical Psychology (2012)

Ambulatory assessment (AA) covers a wide range of assessment methods to study people in their natural environment, including self-report, observational, and biological/physiological/behavioral. AA methods minimize retrospective biases while gathering ecologically valid data from patients' everyday life in real time or near real time. Here, we report on the major characteristics of AA, and we provide examples of applications of AA in clinical psychology (a) to investigate mechanisms and dynamics of symptoms, (b) to predict the future recurrence or onset of symptoms, (c) to monitor treatment effects, (d) to predict treatment success, (e) to prevent relapse, and (f) as interventions. In addition, we present and discuss the most pressing and compelling future AA applications: technological developments (the smartphone), improved ecological validity of laboratory results by combined lab-field studies, and investigating gene-environment interactions. We conclude with a discussion of acceptability, compliance, privacy, and ethical issues.
Colonoscopy at a Combined District General Hospital and Specialist Endoscopy Unit: Lessons from 505 Consecutive Examinations
Authors: Siwan Thomas-Gibson, Catherine Thapar, Syed G Shah, Brian P Saunders
Journal: Journal of the Royal Society of Medicine (2002)

Provisional reports from the Intercollegiate British Society of Gastroenterology National Colonoscopy audit show completion rates of 57–77%for the procedure and poor levels of training and supervision. We prospectively audited all aspects of colonoscopy performed at a combined district general hospital and specialist endoscopy unit. Details of referral, examination, endoscopist, complications and follow-up were recorded and patients were sent questionnaires for long-term follow-up. 505 patients (246 male) underwent colonoscopy by 27 different endoscopists. Their median age was 57 years (range 13–92) and 93%were outpatients. 64% patients were symptomatic and 36%were having surveillance or follow-up colonoscopy. The overall caecal intubation rate was 93%, with little difference between surgeons, physicians and experienced trainees (89%, 92%, 94%) and specialist endoscopists (98%). In only one case was an inexperienced trainee (&lt;100 procedures) unsupervised. Pain scores estimated by the endoscopist were well matched with those given by the patient—medians 29 and 26 (maximum 100) respectively. Median satisfaction score was 96 (maximum 100). Polyp pick-up rate was 26.9%and there were 11 new cancers. 16 (3%) minor immediate complications were recorded—5 oversedation, 6 vasovagal attacks, 3 polypectomy haemorrhages and 2 mucosal injuries (neither requiring treatment). 3 patients died within 6 months of follow-up but no death was colonoscopy related. Completion rates in this setting were adequate for all endoscopists studied. Patient satisfaction with the procedure was high and very few immediate or long-term complications were encountered.