tbuckley/cabot-search huggingface dataset:
Dysphagia
Authors: Bruce S. Trippe
Journal: JAMA (1976)

ACUTE pancreatitis, acute arthritis, or features of the multiple endocrine adenoma syndrome may be the initial manifestations of hyperparathyroidism. It is rare, however, for the simple bulk of a parathyroid adenoma, or its ectopic location, to dominate a patient's initial complaints. In the case reported here, none of the expected symptoms of hyperparathyroidism were present, but the unusual tumor location led to its discovery and to the subsequent chemical verification of primary hyperparathyroidism. <h3>Report of a Case</h3> A 35-year-old woman, previously in excellent health, had a two-year history of increasing difficulty in swallowing and a five-month history of intermittent aching pain radiating from the angle of the right mandible to the right ear. Fatigue, polyuria, polydypsia, constipation, renal calculi, or fractures had not occurred. Family history was noncontributory. Blood pressure was 140/90 mm Hg, funduscopic and slit lamp examination results were normal, hair and nails were normal, and neurofibromata were
Artificial Pneumothorax
Authors: R. L. Sadler
Journal: BMJ (1954)

<h3>Abstract</h3> While navigating their environment, many animals track their angular heading via the activity of heading-sensitive neurons. How internal heading estimates are used to guide navigational behavior, however, remains largely unclear in any species. We found that normal synaptic output from heading neurons in <i>Drosophila</i> is required for flies to stably maintain their trajectory along an arbitrary direction while navigating a simple virtual environment. We further found that if the heading estimate carried by these neurons is experimentally redirected by focal stimulation, the fly typically turns so as to rotate this internal heading estimate back towards the initial angle, while also slowing down until this correction has been made. These experiments argue that flies compare an internal heading estimate with an internal goal angle to guide navigational decisions, highlighting an important computation underlying how a spatial variable in the brain is translated into navigational action. <h3>One Sentence Summary</h3> Flies compare an internal heading estimate with an internal goal angle to guide navigation.
FOOD POISONING IN GREAT BRITAIN
Journal: JAMA (1925)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Treatment of Lyme Disease
Journal: JAMA (2016)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Current European concepts in the management of Helicobacter pylori infection. The Maastricht Consensus Report. European Helicobacter Pylori Study Group.
Journal: Gut (1997)

Abstract There is considerable confusion over the management of Helicobacter pylori infection, particularly among primary care physicians, and numerous European countries lack national guidelines in this rapidly growing area of medicine. The European Helicobacter Pylori Study Group therefore organised a meeting in Maastricht of H pylori experts, primary care physicians and representatives of National Societies of Gastroenterology from Europe to establish consensus guidelines on the management of H pylori at the primary care and specialist levels, and to consider general health care issues associated with the infection. As in previous guidelines, eradication therapy was recommended in all H pylori positive patients with peptic ulcer disease. Additionally, at the primary care level in dyspeptic patients < 45 years old and with no alarm symptoms, diagnosis is recommended by non-invasive means (13C urea breath test, serology) and if H pylori positive the patient should be treated. Moreover, at the specialist level the indications for eradication of H pylori were also broadened to include H pylori positive patients with functional dyspepsia in whom no other possible causes of symptoms are identified by the specialist (after a full investigation including endoscopy, ultrasound and other necessary investigations), patients with low grade gastric mucosa associated lymphoid tissue (MALT) lymphoma (managed in specialised centres) and those with gastritis with severe macro- or microscopic abnormalities. There was consensus that treatment regimens should be simple, well tolerated and achieve an eradication rate of over 80% on an intention to treat basis. It was strongly recommended, therefore, that eradication treatment should be with proton pump inhibitor based triple therapy for seven days, using a proton pump inhibitor and two of the following: clarithromycin, a nitroimidazole (metronidazole or tinidazole) and amoxycillin.
LETTER FROM PARIS.
Authors: None A. B.
Journal: JAMA (1889)

(FROM OUR REGULAR CORRESPONDENT.) Suicide of a Monomaniac—Multiple Wounds—The Cœsarean Operation in Germany versus Induced Premature Labor in France—Saving the Infants —Linear Electrolysis in Urethral Stricture—Camphorated Naphthol. Dr. Langier lately brought to the notice of the Academy of Medicine an extraordinary case of suicidal monomania. It was that of a woman, æt. 63, who was found dead in her room, without any trace indicating struggle or the intervention of a murderer. The wounds to which this woman had succumbed were so numerous and of such nature, that it seemed at first impossible to believe that she had inflicted them herself. The autopsy demonstrated on the contrary in the most manifest manner, that it was not a case of assassination, but suicide. Dr. Langier established on the body, independently of twelve cuts involuntarily inflicted on the palm of the right hand, 142 wounds by a sharp and cutting instrument, 136 were
The Metabolism of Tumours: Investigations from the Kaiser Wilhelm Institute for Biology, Berlin-Dahlem.
Journal: JAMA (1931)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Railroad Transportation.
Authors: None N. W. L.
Journal: JAMA (1897)

Brooklyn, N. Y., June 15, 1897. <h3>To the Editor:</h3> —I send the following clipping from the Brooklyn<i>Times</i>, June 15. 1897, to theJournal, to call it to the attention of the Committee on Transportation: "Single Fare for the Round Trip to Philadelphia via Pennsylvania Railroad on Account of the National Saengerfest.— The Pennsylvania Railroad Company announces that for the Eighteenth National Saengerfest, to be held in Philadelphia June 21 to 24, 1897, it will sell excursion tickets to Philadelphia from all points on its line June 19 to 23 inclusive, good to return until June 26, 1897, inclusive, at a single fare for the round trip. No rate, however, will be reduced to less than 50 cents." Respectfully,
Error in Key Points
Journal: JAMA Network Open (2019)

Michael Phillips, MMedSci; Helen Marsden, PhD; Wayne Jaffe, MB, ChB, FRCS; Rubeta N. Matin, PhD, MBBS, MRCP; Gorav N. Wali, MA, BMBCh, MRCP; Jack Greenhalgh, PhD; Emily McGrath, BMBS, MRCP; Rob James, BSc, RGN; Evmorfia Ladoyanni, PGCME, DTM&H, FRCP; Anthony Bewley, MB ChB, FRCP; Giuseppe Argenziano, MD, PhD; Ioulios Palamaras, MD, PhD
What Does the Medical Student Learn About Sex?
Authors: E. J. H.
Journal: Annals of Internal Medicine (1966)

Editorial Notes1 October 1966What Does the Medical Student Learn About Sex?E. J. H.E. J. H.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-65-4-863_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptDespite some criticism that the recently published monograph by Masters and Johnson (1) on the physiology of coitus and the orgasm does not present its information in the conventional format of scientific reports, it is clear that it does bring new, detailed, and important observations to an area long conspicuously lacking information derived from the direct study of man. The investigations of the Kinsey group, devoted chiefly to quantifying who was doing what and how often, hardly touched on the physiological details of sexual activity, save for such data as penile size in erection. Dickinson'sAtlas of Human Sex Anatomy,...References1. MASTERSJOHNSON WHVE: Human Sexual Response. Little, Brown and Co., Boston, 1966. Google Scholar2. SHEPPEHAIN WMJD: Sex and the medical student. J. Med. Educ. 41: 457, 1966. Google Scholar3. LIEF H: Cited by Sheppe and Hain (2). Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 October 1966Volume 65, Issue 4Page: 863-864KeywordsHuman sexual behavior ePublished: 1 December 2008 Issue Published: 1 October 1966 PDF downloadLoading ...
Journal of Oral Surgery, Chicago
Journal: JAMA (1967)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A Primer for Diabetic Patients: A Brief Outline of the Treatment of Diabetes with Diet and Insulin, Including Directions and Charts for the Use of Physicians in Planning Diet Prescriptions.
Journal: JAMA (1931)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
From the National Institutes of Health
Authors: B. Healy
Journal: JAMA (1991)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Monitoring the blood pH in acute myocardial infarction. The role of acidosis in arrhythmias
Authors: R. A. Cohen
Journal: JAMA (1966)

CLINICIANS recognize the importance of continuous electrocardiographic surveillance in immediately alerting the attending staff of a cardiac catastrophe and in monitoring the various measures designed to restore normal cardiac function.<sup>1-3</sup>Ideally, it would be more desirable to identify the earliest recognizable event that might predict a cardiac arrest. The question raised herein is whether the metabolic acidosis observed after a cardiac arrest (ventricular fibrillation or asystole) is solely secondary or whether this also may precede and contribute to the environment that provokes the development of these arrhythmias. If the latter were true, then such monitoring of the pH would be a valuable adjunct to electrical monitoring of the acutely ill patient. This preliminary paper reports our experience with pH monitoring in critically ill patients with acute myocardial infarction complicated by arrhythmias, pulmonary edema, or cardiogenic shock. <h3>Subjects and Methods</h3> Ten patients with acute myocardial infarction were studied in the
Education
Journal: JAMA (1999)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Contents and Editor’s Summaries
Authors: M Meier, K Holl-Ulrich, B Perras, C Geppert, S Arora, I Norton, B Petersen, J Bosco, D Nelson, P Meier, T Baron, S Lange, C Gostout, D Loeb, M Levy, M Wiersema, N Pochron
Journal: Clinical Gastroenterology and Hepatology (2005)
British Firm Halts Vaccine Manufacture, Research
Authors: Charles Marwick
Journal: JAMA (1990)

JUST AS the United Nations International Children's Emergency Fund announced its Childhood Vaccine Initiative, with a goal of immunizing 90% of the world's children, one of the manufacturers of the vaccines that could make this possible is going out of business. The Wellcome Company, Beckenham, England, has announced that its Wellcome Biotech Division will no longer manufacture vaccines and research new biological products. "Too much litigation and too little profit," comments A. J. Beale, MD, Wellcome Biotech. The decision leaves Britain with only one vaccine manufacturer. The company was one of the defendants in what has become a landmark legal suit in Britain alleging neurological damage caused by the diphtheriatetanus-pertussis (DTP) vaccine. The judgment, handed down in March 1988, was in the company's favor. In Britain, the company is one of the major suppliers of oral polio vaccine and is the sole supplier of the DTP vaccine. It also manufactures
Abstract LB-137: Three-dimensional cytotoxicity assay using magnetic 3D bioprinting for measuring CAR T cell function in heterogeneous solid tumor microenvironments
Authors: Glauco R. Souza, Amer Najjar
Journal: Cancer Research (2019)

Abstract Chromium release assays are routinely utilized to assess cytotoxic activity and function of tumor targeting T cells expressing chimeric antigen receptors (CAR T cells). Although these assays can predict the activity of CAR T cells targeting hematological malignancies, results of such assays do not accurately reflect the limited efficacy of T cell therapy observed against solid tumors. This limitation may be due to the disparity between the in vitro cell culture setting and the complex nature of solid tumor microenvironments and their vascular structure. To this end, we have developed a cytotoxicity assay based on a three-dimensional (3D) cell culture model, facilitated by magnetic 3D bioprinting, to more precisely mimic the complexity of solid tumor microenvironments in vitro. This model can be customized to reflect the heterogeneity of solid tumors by incorporating multiple cell types and immune cells. In these studies, we have demonstrated the feasibility of this assay using CD19-specific CAR T cells specifically targeting CD19+ leukemia cells in a heterogeneous 3D cell culture. We also show the CAR T cells infiltrating and targeting glioblastoma (U87) 3D cultures in real-time with fluorescence microscopy. Incorporation of this assay as a routine cytotoxicity assay will provide new dimensions to rapid immune function assessments by revealing the kinetics of cell killing through time-lapse microscopy, the persistence and targeting patterns of CAR T cells, and cell-specific killing by multicolor fluorescence imaging. This assay is being adapted into a 96-, 384- and 1,536-well formats for high-throughput applications. Citation Format: Glauco R. Souza, Amer Najjar. Three-dimensional cytotoxicity assay using magnetic 3D bioprinting for measuring CAR T cell function in heterogeneous solid tumor microenvironments [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr LB-137.
A MEDICAL EPISODE AT YALE
Journal: JAMA (1989)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal