tbuckley/cabot-search huggingface dataset:
Diet and diabetes
Authors: A. R. Gaby
Journal: JAMA (1981)

<h3>In Reply.—</h3> Dr Deur's letter illustrates the problem faced by an astute and conscientious clinician in managing the sex partner of patients who have sexually transmissible disease. This can be most difficult when the diagnosis is not readily recognized by the patient as a sexually transmitted disease. For example, it is important to identify and treat sexual contacts not only of adult patients with adult ocular chlamydial infections but also the parents of infants with neonatal chlamydial conjunctivitis and the sex partner of patients with mucopurulent cervicitis, epididymitis, Reiter's syndrome, urethral syndrome, pelvic inflammatory disease, and so on. At the present time this situation is probably dealt with most effectively by family physicians who are trained to view the patient in the setting of his family and other relationships. I suspect it may be dealt with least effectively by gynecologists who are trained and expected to deal only with female
Clinical Anatomy.
Authors: Edward A. Edwards
Journal: JAMA (1963)

Rearrangement of medical school curricula since 1930 has resulted not only in a disappearance of courses in applied anatomy but also in a progressive curtailment of time allotted to gross anatomy itself. The present brevity of gross anatomic teaching makes some sort of supplementary course more desirable than ever. Whether this need can be met by specialized courses for interested students, before or after graduation, or whether further anatomic knowledge should be imparted to entire classes, is a moot point. Where the curriculum will admit of a general course in applied anatomy, the problem of scope and detail arises. Dr. Brantigan's book exemplifies the difficulty of any individual being able, by himself, to produce a textbook which will interest the cross section of students. The book, as arranged, is more suitable for a course with emphasis upon lectures than upon dissection by the student—a disadvantage, in the reviewer's opinion. Les
Viral Gastroenteritis
Authors: Neil R. Blacklow, George Cukor
Journal: New England Journal of Medicine (1981)

ACUTE infectious diarrheal illness is the leading cause of disease and death in many areas of the world. Indeed, by one estimate there were 3 to 5 billion cases of diarrhea accounting for 5 to 10 million deaths in Asia, Africa, and Latin America during the year 1977 to 1978.1 Although the cause of a large proportion of this infectious gastroenteritis remains unknown, recently discovered viral agents have joined certain bacteria and parasites on the list of pathogens involved in serious diarrheal disease worldwide.Acute viral gastroenteritis is an extremely common illness that affects all age groups and occurs in . . .
Sixth Biannual Report of the Cochrane Haematological Malignancies Group Focus on Non-Hodgkin Lymphoma
Authors: O. Weingart, F. A. Rehan, H. Schulz, F. Naumann, I. Knauel, C. B. J. Bohlius, A. Engert
Journal: JNCI Journal of the National Cancer Institute (2007)

The Cochrane Haematological Malignancies group (CHMG), based at Cologne, Germany, searches continuously and systematically for clinical trials in the field of hemato-oncology.Randomized controlled trials (RCTs) are identified through electronic search of Medline (OVID gateway) using a broad search filter that covers all topics in hemato-oncology (http://www.chmg.de/html/pdf/topic.pdf)combined with a highly sensitive search filter for randomized studies (Cochrane handbook for systematic reviews of interventions 4.2.5;Appendix 5b.2-phase 1 and phase 2; The Cochrane Collaboration 2005 [updated May 2005] http://www.cochrane.dk/cochrane/handbook/hbook.htm).The search presented here covers publications from July 2006 to March 2007.In these 9 months, 65 controlled clinical trials (RCTs and nonrandomized clinical trials) were published on therapeutic interventions in several hematologic malignancies (e.g., acute leukemia, chronic lymphocytic leukemia, follicular lymphoma).The majority of important trials focused on the addition of rituximab to CHOP-like multiagent chemotherapy (i.e., cyclophosphamide, doxorubicin, vincristine, and prednisone) for non-Hodgkin lymphoma.Downloaded
EXPERIMENTAL ACROMEGALY
Authors: A. J. McLean
Journal: JAMA (1935)

<h3>To the Editor:—</h3> Although it is a minor matter, I cannot forbear to protest concerning the statement that "one of Evans's students working in Cushing's laboratory at Harvard produced experimental acromegaly" in your answer in Queries and Minor Notes (Use of Pituitary Preparations for Increasing Growth,The Journal, February 9, p. 498). The article to which you refer (Studies in Acromegaly: VIII. Experimental Canine Acromegaly Produced by Injection of Anterior Lobe Pituitary Extract,<i>Arch. Surg.</i><b>18:</b>1708 [part 2] 1929) is by Tracy J. Putnam, Edward B. Benedict and Harold M. Teel. The long experimentation to produce an active extract (<i>Am. J. Physiol.</i><b>84:</b>157 [Feb.] 1928) and the planning of the work was done by Dr. Putnam, with the fragmentary assistance of Dr. Benedict and (the then) Mr. Teel. Dr. Teel's contributions to endocrinology, and the splendid bulk of Dr. Evans's own work, are such that I know these
Hemolysis Associated With 25% Human Albumin Diluted With Sterile Water—United States, 1994-1998Nosocomial Group A Streptococcal Infections Associated With Asymptomatic Health-Care Workers—Maryland and California, 1997Hemolysis Associated With 25% Human Albumin Diluted With Sterile Water—United States, 1994-1998Nosocomial Group A Streptococcal Infections Associated With Asymptomatic Health-Care Workers—Maryland and California, 1997
Journal: JAMA (1999)
Do Waste Incinerators Induce Adverse Respiratory Effects? An Air Quality and Epidemiological Study of Six Communities
Authors: Carl M. Shy, Darrah Degnan, Donald L. Fox, Shaibal Mukerjee, Milan J. Hazucha, Brian A. Boehlecke, Dietrich Rothenbacher, Patsy M. Briggs, Robert B. Devlin, Dennis D. Wallace, Robert K. Stevens, Philip A. Bromberg
Journal: Environmental Health Perspectives (1995)
Establishing the cause of genitourinary symptoms in women in a family practice. Comparison of clinical examination and comprehensive microbiology
Authors: A. O. Berg
Journal: JAMA (1984)

We conducted a prospective study comparing the diagnostic yield of standard clinical examinations and of comprehensive microbiological studies in establishing the etiology of genitourinary (GU) symptoms and the prevalence of GU tract infections in 204 women seen in a university-based family practice. Two thirds were initially seen with GU symptoms and one third were seen for routine examinations. In each case we obtained demographic and historical information, a physical examination, and a variety of laboratory tests, including research procedures not commonly available. Diagnoses considered were urinary tract infection and sterile pyuria; trichomonal, yeast, and nonspecific vaginitis; and GU tract infection with<i>Neisseria gonorrhoeae, Chlamydia trachomatis</i>, or herpes simplex virus. Using strategies commonly employed in practice, we reached a diagnosis in only 34% of symptomatic women, a figure rising to 66% when selected, nonroutine laboratory examinations were added. (<i>JAMA</i>1984;251:620-625)
Errata
Journal: JNCI Journal of the National Cancer Institute (1974)

In the Brief Communication: “Release of Mouse Leukemia-Sarcoma Virus From Synchronized Cells,” by S. Panem and W. H. Kirsten, on page 563, second column, line 20 should read “medium and 2 × 10−5m …” (not “2 × 10−3m”).
The Goulstonian Lectures ON DEATH BY ELECTRIC CURRENTS AND BY LIGHTNING: Delivered before the Royal College of Physicians of London
Authors: A. J. Jex-Blake
Journal: BMJ (1913)

The Mode of Death by Lightning.IT would seem as if sudden death by lightning might occur in at any rate three different ways-by failure of the heart, by failure of the respiration, and by failure of botlh togetlher.In the vast majority of cases the senses are lost at once, and in most deatlh takes place very rapidly if at all.The extreme suddenness with which it must have occurred, as proved by the natural position of the corpse and its placid expression, has often been noted.As is the case in non-fatal strokes, there is reason to suppose that the nervous system is profoulndly affected, tlhough no microscopic lesions may be demonstrable.1. Death by failure of the heart, whiclh nmay be sup-
Clinical history as a screening test for ankylosing spondylitis
Authors: A. Calin
Journal: JAMA (1977)

A controlled study of 138 subjects demonstrated that the clinical history may be sensitive (95%) and specific (85%) in the differential diagnosis of ankylosing spondylitis when reliance on five specific historic features is made. Back pain that is insidious in onset, in a patient younger than 40 years, persisting for at least three months, associated with morning stiffness and improving with exercise is characteristic of inflammatory spinal disease. (<i>JAMA</i>237:2613-2614, 1977)
Secretin, Cholecystokinin and Newer Gastrointestinal Hormones
Authors: Phillip L. Rayford, Thomas A. Miller, James C. Thompson
Journal: New England Journal of Medicine (1976)

New HormonesIn addition to the hormones already discussed, several polypeptides have recently been identified and physiologic phenomena observed suggesting that other substances may be involved with the initiation and modulation of the normal digestive process. These "candidate hormones," as Grossman153 , 154 calls them, include glucagon, gastric inhibitory polypeptide (GIP), vasoactive intestinal polypeptide (VIP), bombesin, motilin, chymodenin, bulbogastrone, entero-oxyntin and pancreatic polypeptide. Because somatostatin-like immunoreactivity has been found to be present in the gut,155 we have added it to the group.What makes a candidate hormone a true hormone? Grossman154 says,..., it must be shown that the peptide in question . . .
Abstract 1236: A Molecular and Functional Basis for Focal Arrhythmogenesis in Heart Failure-associated Atrial Fibrillation
Authors: Yung-Hsin Yeh, Reza Wakili, Xiao Yan Qi, Denis Chartier, Stefan Kääb, Ursula Ravens, Stanley Nattel, Dobromir Dobrev
Journal: Circulation (2007)

Introduction: Heart failure (HF) frequently causes atrial fibrillation (AF) and focal sources of unknown mechanism have been implicated. Here, we studied the potential role and molecular mechanisms of Ca 2+ handling abnormalities. Methods: Ca 2+ handling (microfluorescence, Indo-1 AM) and related protein expression (Western blot) were assessed in left atria of 20 dogs with ventricular tachypacing (240 bpm × 2 wks)-induced HF and 20 controls (CTLs). Whole-cell perforated-patch was used to record action potentials (APs), delayed afterdepolarizations (DADs) and triggered activity. Results : HF increased [Ca 2+ ] i transient amplitude from 239±24 to 444±43* nM (*P&lt;0.05), and [Ca 2+ ] i release by 10 mM local caffeine puffs (an index of SR Ca 2+ content) from 849±71 (CTL) to 1574±169* nM (HF). Spontaneous Ca 2+ release events increased from 1.8±0.5 (CTL) to 10.7±2.1* events/run (HF). HF significantly increased APD (by ~40% at 1 Hz). DADs and triggered activity were more common in HF (15.2±2.6 triggered APs/run, vs CTL 0.4±0.2*), and were abolished by ryanodine (10 μM), but not by the I f -blocker Cs + (2 mM). HF caused profound changes in protein expression of key Ca 2+ handling and regulatory proteins (Table ). Calsequestrin, the major SR Ca 2+ -binding protein, was reduced by 32%*. Fractional RYR2 PKA (Ser2809) phosphorylation decreased by 63%*, whereas CaMKII (Ser2815) RYR2 phosphorylation increased by 221%*. The catalytic and regulatory (RII) PKA subunits were downregulated by 15%* and 73%*, whereas expression and autophosphorylation (Thr287) of CaMKIIδ were increased by 45%* and 81%* respectively. NCX1, SERCA and total, PKA and CaMKII phosphorylated SERCA-regulatory phospholamban were unchanged by HF. Conclusions: HF causes profound changes in regulation and expression of atrial Ca 2+ handling proteins, producing increased SR Ca 2+ load and release, along with DADs and triggered activity that may account for focal mechanisms that initiate and/or sustain HF-related AF.
Sport concussion assessment tool - 5th edition
Journal: British Journal of Sports Medicine (2017)

The SCAT5 is a standardized tool for evaluating concussions designed for use by physicians and licensed healthcare professionals 1 .The SCAT5 cannot be performed correctly in less than 10 minutes.If you are not a physician or licensed healthcare professional, please use the Concussion Recognition Tool 5 (CRT5).The SCAT5 is to be used for evaluating athletes aged 13 years and older.For children aged 12 years or younger, please use the Child SCAT5.Preseason SCAT5 baseline testing can be useful for interpreting post-injury test scores, but is not required for that purpose.Detailed instructions for use of the SCAT5 are provided on page 7. Please read through these instructions carefully before testing the athlete.Brief verbal instructions for each test are given in italics.The only equipment required for the tester is a watch or timer.This tool may be freely copied in its current form for distribution to individuals, teams, groups and organizations.It should not be altered in any way, re-branded or sold for commercial gain.Any revision, translation or reproduction in a digital form requires specific approval by the Concussion in Sport Group. Recognise and RemoveA head impact by either a direct blow or indirect transmission of force can be associated with a serious and potentially fatal brain injury.If there are significant concerns, including any of the red flags listed in Box 1, then activation of emergency procedures and urgent transport to the nearest hospital should be arranged.
LONG-TERM SEQUENTIAL DEFERIPRONE AND DEFERASIROX THERAPY IN TRANSFUSION-DEPENDENT THALASSEMIA PATIENTS: A PROSPECTIVE CLINICAL TRIAL
Authors: A. Vitrano, G. B. Ruffo, D. G. DʼAscola, V. Caruso, A. Filosa, N. Masera, L. Pitrolo, P. Rigano, L. Cuccia, R. Di Maggio, A. Maggio
Journal: HemaSphere (2019)
THE RELATIONS BETWEEN ALCOHOLIC INDULGENCE AND VENEREAL DISEASE.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Power pulse inversion and pulse inversion: Do these new techniques allow the recording of contrast replenishment curves? Thomas Schlosser, Klaus Tiemann, Stefanie Kuntz-Hehner, Christoph Pohl, Stefan Lohmaier, Christian Veltmann, Jon Goenechea, J�rg K�ster, Harald Becher. University of Bonn, Bonn, Germany
Journal: Journal of the American College of Cardiology (2001)
Medical Philately
Authors: Stanley P. Bohrer
Journal: JAMA (1961)

<h3>To the Editor:—</h3> As a collector of postage stamps related to medical topics I was pleased to see 2 recent additions toThe Journal—medical stamps appearing above the Foreign Mail section and the<b>2</b>recent biographical sketches by J. A. Mirt. I have checked many sources, including the Library of Congress, but I am unable to identify the reference in the July 8 issue (<i>JAMA</i><b>177:</b>26) to "Mirt, J. A.: 'Medical Pathfinders on Postage Stamps.' " Could you please tell me where this appears? On the Foreign Mail page, do you think it would be of interest to identify the persons or places depicted by the stamps?
Incorrect Correspondence Address
Journal: JAMA Surgery (2017)

Audree B. Tadros, MD; Wei T. Yang, MD; Savitri Krishnamurthy, MD; Gaiane M. Rauch, MD, PhD; Benjamin D. Smith, MD; Vicente Valero, MD; Dalliah M. Black, MD; Anthony Lucci Jr, MD; Abigail S. Caudle, MD; Sarah M. DeSnyder, MD; Mediget Teshome, MD; Carlos H. Barcenas, MD; Makesha Miggins, MD; Beatriz E. Adrada, MD; Tanya Moseley, MD; Rosa F. Hwang, MD; Kelly K. Hunt, MD; Henry M. Kuerer, MD, PhD
The Wassermann Test.
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Saturated fatty acids in vegetable oils. Council on Scientific Affairs
Journal: JAMA (1990)

Concern has been expressed about the "atherogenicity" of coconut and/or palm oil in food products. Saturated fatty acids are found primarily in animal products and in "tropical oils" (coconut, palm, and palm kernel oils). Composition of the total diet over an extended period determines nutritional status and contribution to health. Specific foods and/or food ingredients need to be evaluated within the context of a person's total dietary pattern over time. Persons attempting to limit saturated fatty acid intake should be aware of the high content of saturated fatty acids in tropical oils. The American Medical Association is on record as supporting fatty acid labeling when cholesterol content is declared and cholesterol labeling when fatty acid content is declared. The American Medical Association has supported, and continues to support, voluntary efforts to increase public awareness of the composition and nutritional value of foods.
THE JOURNAL TRAIN.
Journal: JAMA (1895)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 2375: Oseltamivir Treatment Reduces the Risk of Stroke Following Influenza Infection
Authors: Mohammad Madjid, Suellen Curkendall, William A Blumentals
Journal: Circulation (2007)

Background: Influenza infection is known to trigger the incidence of heart attack and ischemic stroke. Seasonal influenza epidemics are associated with an increased risk of cardiovascular diseases, including ischemic stroke. Influenza vaccine has been shown to reduce the risk of myocardial infarction and stroke. The antiviral drug oseltamivir has been shown to reduce the severity and duration of influenza symptoms and the risk of hospitalization in patients diagnosed with influenza. We conducted a retrospective cohort study to examine the impact of oseltamivir treatment on the risk of stroke and transient ischemic attack (TIA) following influenza in adults. Methods: Anonymous, patient-level medical and pharmaceutical claims data from May 2000 to September 2006 were obtained from a managed care database. We selected patients diagnosed with influenza who were prescribed oseltamivir within 1 day before or 2 days after influenza diagnosis (oseltamivir group) and compared them to patients who were not prescribed any antiviral treatment for influenza (control group). The incidence of stroke or TIA in the 6 months following influenza diagnosis in the two groups was compared using multivariate analyses adjusted for factors including age, gender, and history of risk factors for stroke, and differences expressed as hazard ratios (HR) with 95% confidence intervals (CI). Results: There were 151,930 eligible patients aged ≥18 years: 49,238 patients in the oseltamivir group, and 102,692 patients in the control group. Treatment with oseltamivir was associated with a significant 29% reduction in the risk of stroke or TIA at 6 months following an influenza diagnosis (HR=0.71; 95% CI 0.61– 0.81). Significant reductions in risk were also observed at 1 and 3 months. The effect of oseltamivir on the risk of stroke or TIA was more pronounced in patients aged ≥40 years: significant risk reductions were observed at months 1 (HR=0.50; 95% CI 0.37– 0.68), 3 (HR=0.62; 95% CI 0.51– 0.75), and 6 (HR=0.73; 95% CI 0.63– 0.84). In those aged &lt;40, HR at 6 months was 0.56 (95% CI: 0.37– 0.86). Conclusions: Prescription of oseltamivir after influenza is associated with a reduced risk of stroke or TIA. Our results, once confirmed by randomized studies, offer a novel approach to prevent stroke and TIA.
License with the poetic
Authors: S. Vaisrub
Journal: JAMA (1976)

WOULD that poets showed greater interest in medicine! How often have we wished that this were so when, on scanning a poem, our eyes would be arrested by a line or a stanza with medical connotations wasted in a nonmedical context. Think of the medical potential of "Why so pale and wan fond lover/Prythee, why so pale?" A great poem on the etiology of anemia might have replaced the pretty, yet inconsequential love song, had Sir John Suckling studied medicine. Ponder how John Keats, though himself a physician, failed to make something hematologic or psychosomatic of his memorable "I saw<i>pale</i>kings and princes too/<i>Pale</i>warriors, death-<i>pale</i>were they all." Must the physician then give up for lost the little nuggets of poetry that could have been set into a medical ornament? Certainly not. He can still salvage these medical gems by quoting them out of context in