tbuckley/cabot-search huggingface dataset:
Cholera—International Travel, 1992
Journal: JAMA (1992)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Legal aspects of the decision not to prolong life
Authors: G. P. Fletcher
Journal: JAMA (1968)

New medical techniques for prolonging life force both the legal and medical professions to reexamine their traditional attitudes toward life and death. The new set of problems emerges from the following recurrent situation: a comatose patient has a flat electroencephalogram reading; according to the best judgment, he has an infinitesimal chance of recovery; he can be sustained by intravenous therapy. What should his physician do? And in making his decision, how much weight should the physician give to the wishes of the family, to the financial condition of the family, and to the prospect that his time might be profitably used in caring for patients with a better chance for recovery? It would be a mistake to think that our legal tradition contains clear answers to these questions. If this type of case demands moral sensitivity of the physician, it demands much more of the legal theorist and of the
<i>The Principles ana Practice of Operative Surgery</i>. By Stephen Smith, A. M., M. D., Professor of Clinical Surgery in the University of the City of New York; Surgeon to the Bellevue and St. Vincent’s Hospitals, New York; Consulting Surgeon to St. Elizabeth’s Hospital, to the Foundling Asylum, to the Infant’s Asylum; New York State Commissioner in Lunacy, &amp;c. New and thoroughly revised edition. Illustrated with one thousand and five woodcuts. Philadelphia: Lee Brothers &amp; Co., 1887
Journal: American Journal of Psychiatry (1888)
Highlights
Journal: JAMA Internal Medicine (2018)

Bindman and Cox performed this retrospective cohort analysis to investigate if there was an association between the implementation of transitional care management payment codes and changes in cost and health outcomes for Medicare beneficiaries discharged to the community from medical facilities.Results showed that despite benefits of transitional care management services, use remains low, and the adjusted total Medicare costs and mortality were higher among those beneficiaries who did not receive transitional care management services compared with those who did following an eligible discharge.Huckfeldt and colleagues provide the Invited Commentary. Invited Commentary 1171 Effectiveness of Mailed Screening Outreach Program 1174In this cluster randomized clinical trial, Coronado and colleagues examined effectiveness of mailing a fecal immunochemical test (FIT) to patients due for colorectal cancer screening when implemented in busy community clinic practices in Oregon and California as part of standard care.Effectiveness was measured as clinic-level proportions of adults who completed a FIT, and secondarily, any colorectal cancer screening during the evaluation interval.Compared with usual care clinics, intervention clinics had significantly higher adjusted clinic-level proportion of participants who completed a FIT and any colorectal cancer screening.Redberg provides the Editor's Note.
Nursing: new power, old problems
Authors: E. Friedman
Journal: JAMA (1990)

NURSING, as it enters the 1990s, faces a crossroad. It is more in demand than ever, but its leaders question the appropriateness of much of that demand. It seeks to end the shortages that have occurred through much of this century, but also wants to raise minimum standards for entry into the profession. Its traditional dilemmas of external image and internal identity continue to cause conflicts. Circumstances are such that nursing and medicine should be closer than ever, but they are fighting instead. Yet, nursing is gaining in strength, and may be in a better position to address these issues than it has ever been. There are several sources of nursing's growing power, but the key factor is that at the moment, there do not appear to be enough nurses to go around. The US Department of Health and Human Services Secretary's Commission on Nursing, which issued its final report
Abstract 3527: Combined high-throughput DNA genotyping and protein quantification in single cancer cells
Authors: Benjamin Demaree, Cyrille Delley, David Ruff, Sebastian Treusch, Dennis Eastburn, Keith Jones, Adam Abate
Journal: Cancer Research (2019)

Abstract Clonal genetic diversity is a hallmark of tumor biology. In many cancers, clonal evolution has been implicated as a driver of tumor initiation, progression, and relapse, and can be a prognostic indicator of disease outcome. Cancer cells are also phenotypically heterogeneous, constituting features which can enable intravasation and metastasis, or which can impart immunoevasive capabilities. Clinically, a combination of single-cell genotype and phenotype data from cancer biopsies could provide valuable insights into oncological disease states, such as metastatic risk or drug response. Here we present a multiomic technology for the simultaneous, high-throughput capture of DNA genotype and protein information from single cells, demonstrated through the analysis of acute myeloid leukemia (AML) derived cell lines. The experimental workflow leverages the high-throughput single-cell microfluidic droplet technology on the Mission Bio Tapestri platform, a system optimized to conduct multiplex targeted genomic DNA amplification from &amp;gt;50 AML-associated loci. In our modified workflow, cells are stained with a pool of monoclonal antibodies conjugated with barcoded oligonucleotides, enabling a sequencing-based readout of single-cell protein signatures. The sequencing data is analyzed with a bioinformatic pipeline that separates antibody signal from targeted genotyping data on a cell-by-cell basis. We find that on a mixed population of myelogenous leukemia cells and B-cells, single-cell genotype information effectively distinguishes between cell lines, while the protein data independently recapitulates the biological signal from conventional flow cytometric methods. In conclusion, this technology opens up a new era for discovery using multiomic analysis of the complex relationships between genotype and phenotype in cancer, paving the way for future studies analyzing primary tissue samples. Citation Format: Benjamin Demaree, Cyrille Delley, David Ruff, Sebastian Treusch, Dennis Eastburn, Keith Jones, Adam Abate. Combined high-throughput DNA genotyping and protein quantification in single cancer cells [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 3527.
Nafcillin-tolerant Staphylococcus epidermidis endocarditis
Authors: J. D. Arthur
Journal: JAMA (1982)

RESISTANCE of<i>Staphylococcus aureus and S epidermidis</i>organisms to penicillin is known to be mediated by several different mechanisms. Resistance due to production of β-lactamase (penicillinase) resulting in penicillin inactivation was recognized with<i>S aureus</i>in the early 1960s.<sup>1</sup>"Intrinsic" resistance to the penicillinase-resistant penicillins (PRPs) has been observed in both<i>S aureus</i>and<i>S epidermidis</i>for more than ten years.<sup>2</sup>Recently, strains of S aureus described as "tolerant" to PRPs have been reported.<sup>3</sup>This tolerance is manifested by a wide disparity between the concentration of penicillin required to inhibit growth of the organism and that required for killing it. Routine antibiotic sensitivity testing shows these strains to be sensitive to PRPs. The minimal inhibitory concentration (MIC) is well within the therapeutic range of these drugs, but the minimal bactericidal concentration (MBC) is 32 times the MIC or greater, indicating a required therapeutic level not practically achievable
The 1932 Year Book of Radiology. Diagnosis.
Journal: JAMA (1933)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Cherapeutics.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hyperglycemic nonketotic coma in insulin-dependent diabetes mellitus. Report of a patient with previous history of diabetic ketoacidosis and pituitary stalk section
Authors: H. D. Kolodny
Journal: JAMA (1968)

Hyperglycemic nonketotic coma developed in a young man ten weeks after an episode of diabetic ketoacidosis and four weeks after successful pituitary stalk section. This is the first recorded instance of this syndrome occurring in a patient with a history of insulin-dependent diabetes mellitus. A possible relation between the stalk section and the altered responses to accelerating hyperglycemia is considered.
Hyperalimentation
Authors: James C. M. Chan
Journal: JAMA (1972)

<h3>To the Editor.—</h3> In regard to the first point, the intended reference is to our previous work. We concede that reference to their work was a technical error. In regard to the second point, we concede reference to the paper of Albert and Winters was used inappropriately; the intended reference is to Rodriguez-Soriano.<sup>1</sup>Recent studies in our laboratory<sup>2</sup>employing independent means to measure the rate of endogenous acid production in infants has not led us to alter the figure employed in our article. In regard to the third point, the observation that the titratable acidity of Fre-Amine is higher in our laboratory as compared to that of Dr. Heird et al is most likely due to the differences in the concentration used. The values Dr. Heird quoted are from our laboratory. The excessive gain of acid is amply shown in our studies; take for example, case 1, with
68 SURGICAL RESECTION VS. PERCUTANEOUS ABLATION FOR HEPATOCELLULAR CARCINOMA: A PRELIMINARY REPORT OF THE JAPANESE NATIONWIDE SURVEY
Authors: K. Hasegawa, T. Takayama, N. Kokudo, S. Arii, M. Okazaki, K. Okita, M. Omata, M. Kudo, M. Kojiro, Y. Nakanuma, K. Takayasu, M. Monden, Y. Matsuyama, I. Ikai, T. Ichida, M. Sakamoto, O. Nakajima, M. Makuuchi
Journal: Journal of Hepatology (2009)
Abstract 4628:Efficacy of Bepridil in Patients with Symptomatic Brugada Syndrome-The Relationship Between The Effects of Bepridil and SCN5A Mutation-
Authors: Masato Murakami, Nobuhiro Nishii, Satoshi Nagase, Kazufumi Nakamura, Hiroshi Morita, Takefumi Oka, Tohru Ohe, Kengo F Kusano
Journal: Circulation (2008)

Background : It has been reported that Bepridil prevents ventricular fibrillation (VF) in patients with symptomatic Brugada syndrome (BrS) because it depresses I to current. But the relationship between the effects of Bepridil and SCN5A mutation in patients with BrS is not known. Methods and Results : Low-dose (100mg/day) Bepridil was administered for seven patients (three with SCN5A mutation, four without SCN5A mutation; all men; age, 33 to 74 years) of BrS. If the effect was insufficient, Bepridil was escalated to 200mg/day. Three patients with SCN5A mutation had many VF episodes (patient A 22/72, B 11/38 and C 10/26; VF events/months) before low-dose Bepridil. But after low-dose Bepridil, most VF episodes were controlled (patient A 0/27, B 1/30 and C 1/29; VF events/months). All of four patients (patient D, E, F and G) without SCN5A mutation had relapses of VFs in a short term after low-dose Bepridil. One patient (patient E) suspected to have proarrhythmia needed cessation of Bepridil. In the other three patients, 200mg/day of Bepridil was administered. It was effective for one patient (patient G), but not effective for the other two patients (patient D and F). In patients with SCN5A mutation, parameters of signal-averaged electrocardiography (SAECG) were improved after low-dose Bepridil. But there was no improvement in SAECG of patients without SCN5A mutation (figure ). Conclusion : In patients of BrS with SCN5A mutation, low-dose Bepridil improved parameters of SAECG and controlled VF occurrence.
Software
Authors: Michael Frank
Journal: JAMA (1989)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Editor's Choice
Journal: British Journal of Dermatology (2016)

of serological tests and diagnoses for 4774 cases of autoimmune bullous diseasesTh is study by Hashimoto and colleagues from Kurume University School of Medicine summarized immunological diagnostics for 4774 patients with various autoimmune bullous diseases (AIBDs) from their cohort of 5063 patients with diffi cult AIBDs.Th ese cases were collected over a 19-year period.Serological studies included various immunofl uorescence, immunoblotting and enzyme-linked immunosorbent assays to make fi nal diagnoses.Th ese techniques were successful in establishing a fi nal diagnosis for approximately three-quarters of the diffi cult cases of AIBD; the remaining cases could not be diagnosed.Using the results, these authors suggest a classifi cation of AIBDs, and also propose the most effi cient algorithm of immunological tests for the diagnosis of various AI-BDs.Th ey concluded that this study confi rms that their immunological approach was useful in making a diagnosis for most patients with AIBD.
David Oliver: Doctors need intergenerational solidarity
Journal: BMJ (2016)

Doctors need intergenerational solidarityTwo popular books followed the latest financial crash and austerity drive: The Pinch 1 and Jilted Generation 2 urged those under 35 or so to protest against the self interest of baby boomers.Born from 1946 to 1964, boomers had allegedly saddled younger generations with public debt, student tuition fees, job insecurity, and an unreachable housing ladder-while boomers were growing asset and pension rich.
Pharmakon
Authors: T. Jackson
Journal: BMJ (2003)

A Wellcome Trust exhibition at the TwoTen Gallery, 210 Euston Road, London NW1, until 6 February 2004 Rating:![Graphic][1]</img>![Graphic][2]</img> This exhibition claims to explore the downside to our ever-increasing levels of pill consumption. It purports to ask whether our dependence on prescription medicines could lead to a culture of “selling sickness,” allied with an increasing unwillingness to take responsibility for our own health. … [1]: /embed/inline-graphic-1.gif [2]: /embed/inline-graphic-2.gif
Scleral Lenses Invade 'Domain' of Contacts
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Importance of Coxsackie Viruses in Human Disease, Particularly Herpangina and Epidemic Pleurodynia
Authors: Robert J. Huebner, Edward A. Beeman, Roger M. Cole, Paul M. Beigelman, Joseph A. Bell
Journal: New England Journal of Medicine (1952)

Diseases Produced by Coxsackie Viruses Relation to Poliomyelitis and "Poliomyelitis-Like" Illnesses Most important of the attributes of Coxsackie viruses is that of their relation to illness. Whether any or all of these viruses cause illness and, if so, what sort of illness are matters for careful consideration. It has already been pointed out that the viruses are found in many people in many parts of the world: their very ubiquity is therefore a factor of importance. Furthermore, their isolation from feces is a simple laboratory procedure; as a result, they have been widely, though usually sporadically, reported in persons suffering . . .
Is Your Patient Fit?
Journal: JAMA (1967)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Possible Dangers of the Bubble Fountain
Journal: JAMA (2016)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal