Staphylococcal Endocarditis
Authors: JAMES J. RAHAL
Journal: Annals of Internal Medicine (1981)

Letters and Corrections1 August 1981Staphylococcal EndocarditisJAMES J. RAHAL JR, M.D., MICHAEL S. SIMBERKOFF, M.D.JAMES J. RAHAL JR, M.D.Search for more papers by this author, MICHAEL S. SIMBERKOFF, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-95-2-239_3 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Parker and Fossieck (1) have described successful treatment of 35 episodes of staphyloccal endocarditis with a regimen of intravenous antibiotic for 2 weeks followed by oral therapy for 4 weeks. Their criteria for the use of oral therapy after 2 weeks were "defervescence, improvement in clinical status and sterile blood cultures . . . monitored by in vitro determination of serum antibacterial activity." In 31 of 35 episodes, the patients were users of intravenous drugs, and in 31 instances there was evidence of tricuspid valve infection. The clinical course and prognosis of staphylococcal endocarditis are well known...References1. PARKERFOSSIECK RB. Intravenous followed by oral antimicrobial therapy for staphylococcal endocarditis. Ann Intern Med. 1980;93:832-4. LinkGoogle Scholar2. WATANAKUNAKORNBAIRD CI. Prognostic factors in Staphylococcus aureus endocarditis and results of therapy with a penicillin and gentamicin. Am J Med Sci. 1977;273:133-9. CrossrefMedlineGoogle Scholar3. MENDAGORBACH KS. Favorable experience with bacterial endocarditis in heroin addicts. Ann Intern Med. 1973;78:25-32. LinkGoogle Scholar1. RAJASHEKARAIAHRICERAOMARSHRAMAKRISHNAKALLICK KTVDBC. Clinical significance of tolerant strains of Staphylococcus aureus in patients with endocarditis. Ann Intern Med. 1980;93:796-801. LinkGoogle Scholar2. WATANAKUNAKORNGLOTZBECKER CC. Enhancement of the effects of anti-staphylococcal antibiotics by aminoglycosides. Antimicrob Agents Chemother. 1974;6:802-6. CrossrefMedlineGoogle Scholar3. BRADLEYMAYHALLDALTON JCH. Incidence and characteristics of antibiotic-tolerant strains of Staphylococcus aureus. Antimicrob Agents Chemother. 1978;13:1052-7. CrossrefMedlineGoogle Scholar4. ROZENBERG-ARSKAFABIUSBEENS-DEKKERSDUURSMASABATHVERHOEF MGASLJ. Antibiotic sensitivity and synergism of "penicillin-tolerant" Staphylococcus aureus. Chemotherapy. 1979;25:352-5. CrossrefMedlineGoogle Scholar1. WATANAKUNAKORNBAIRD CI. Prognostic factors in Staphylococcus aureus endocarditis and results of therapy with a penicillin and gentamicin. Am J Med Sci. 1977;273:133-9. CrossrefMedlineGoogle Scholar2. ABRAMSSKLAVERHOFFMANGREENMAN BATR. Single or combination therapy of staphylococcal endocarditis in intravenous drug abusers. Ann Intern Med. 1979;90:789-91. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: JAMES J. RAHALJR, M.D.; MICHAEL S. SIMBERKOFF, M.D.Affiliations: Manhattan Veterans Administration Medical Center New York, NY 10010 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 August 1981Volume 95, Issue 2Page: 239-240KeywordsAntibioticsBloodDrug usersDrugsEndocarditis ePublished: 1 December 2008 Issue Published: 1 August 1981 PDF downloadLoading ...