tbuckley/cabot-search huggingface dataset:
INFANTILE CONSTIPATION.
Authors: J. WELLINGTON BYERS
Journal: JAMA (1897)

The purpose of this paper is to present some observations bearing upon that form of habitual constipation in infants which is, as I conceive it, associated with if not ascribable to defective conditions connected with the digestion and assimilation of certain elements in the food. There are some reasons of an anatomic and physiologic character, why we would naturally expect to find constipation in infants of frequent occurrence. The muscular structure of the infant bowel is feeble and thin, and possesses but little capacity to propel the feces onward when they have once assumed consistency and bulk. The descending colon of the child is also longer than other parts of this bowel and readily permits of dilatation and sagging when there are accumulations within. From these physical and anatomic causes, together with the fact that the intestinal juices in general are very much lessened in children, we can easily perceive
A Comparison of Patients with Chronic Fatigue Syndrome Attending Separate Fatigue Clinics Based in Immunology and Psychiatry
Authors: P D White, A J Pinching, A Rakib, M Castle, B Hedge, S Priebe
Journal: Journal of the Royal Society of Medicine (2002)

Hospital clinics for patients with chronic unexplained fatigue are held in departments of various disciplines. This causes difficulties for referrers in choosing the appropriate clinic and for researchers in generalizing findings from one type of clinic to others. We randomly selected 37 outpatients attending an immunology fatigue clinic and 36 outpatients attending a psychiatry fatigue clinic, all of whom had chronic fatigue syndrome. We compared demographic factors, symptoms, disability, quality of life, psychological distress and illness attributions. The patients from the two clinics were closely similar in their specific symptoms, disability, quality of life, psychological distress and previous attendance to mental health professionals. Psychological distress was high and equal in the two samples. The proportion of men was greater among patients attending the immunology clinic. In a post-hoc analysis, 64% of immunology attenders attributed their fatigue to physical factors, compared with 31% of psychiatry clinic attenders (χ 2 =6.35, 1 d.f., P=0.01). These findings suggest that research data from one type of chronic fatigue clinic can be generalized to others. Clinically similar patients are referred to different clinics, and the choice of clinic may be influenced by the patients’ illness beliefs. The high levels of emotional distress suggest that psychosocial management is as important as physical management in hospital outpatients with chronic fatigue syndrome, irrespective of its aetiology.
Ugeskrift for Laeger, Copenhagen
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Guest Authorship, Mortality Reporting, and Integrity in Rofecoxib Studies
Authors: Christopher J. Hawkey
Journal: JAMA (2008)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
State Board Examinations.
Journal: JAMA (1898)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Care of chronic psychotics.
Journal: BMJ (1971)

Care of Chronic PsychoticsThe year 1961 was for some an annus mirabilis in the history of British psychiatry.In that year three separate papers`w ere published by different authors in which forecasts were made, based on statistical analyses of current trends, of the future needs of our mental hospitals in terms of beds.There was a remarkable degree of accord in the conclusions arrived at.Of the three the most important was that by G. C. Tooth and Miss E. Brooke,3 if only because it shaped official administrative policy.Their pre- diction for the beds needed is specifically referred to in the Hospital Plan of 1962,4 which states (p.5): "A ratio of 18 (instead of 34) per thousand population has been taken as the probable requirements by 1975."So the parting knell of half our mental hospitals was sounded, and as they were one by one razed to the ground5 it was expected that their function would be split between the general hospitals and community services-or community care.
Disseminated intravascular coagulation in prostatic carcinoma reversed by ketoconazole
Authors: M. R. Litt
Journal: JAMA (1987)

DISSEMINATED intravascular coagulation (DIC) is a well-recognized complication of malignant neoplasms. Between 13% and 25% of the patients with chronic DIC have underlying prostatic carcinoma.<sup>1,2</sup>The mechanism of DIC in these patients appears to be related to release of thromboplastins from prostatic tissue.<sup>3</sup> The treatment of DIC involves prompt identification, with control or eradication of the underlying disease process. Correction of circulatory volume, hemostatic elements, and possible sepsis is mandatory. The use of heparin sodium (Panheparin), ε-aminocaproic acid, and exogenous estrogens in DIC related to prostatic carcinoma remains controversial.<sup>4</sup> The following report describes the use of ketoconazole in the treatment and reversal of DIC associated with prostatic carcinoma. <h3>Report of a Case</h3> An 82-year-old man with metastatic prostatic cancer was transferred to The Johns Hopkins Hospital, Baltimore, for evaluation of a coagulopathy and hematuria. Two years previously, the patient developed symptoms of urinary obstruction and underwent a
Evaluation of impulse oscillation system: comparison with forced oscillation technique and body plethysmography
Authors: J. Hellinckx, M. Cauberghs, K. De Boeck, M. Demedts
Journal: European Respiratory Journal (2001)

The impulse oscillation system (IOS) has been developed recently to measure respiratory system resistance ( R rs ) and reactance ( X rs ) at different frequencies up to ≥25 Hz. IOS has, however, not been validated against established techniques. This study compared IOS with the classical pseudorandom noise forced oscillation technique (FOT) and body plethysmographic airway resistance ( R aw ) in 49 subjects with a variety of lung disorders and a wide range of R aw (0.10–1.28 kPa·L −1 ·s). R rs,IOS was slightly greater than R rs,FOT , especially at lower frequencies, with a mean±sd difference at 5–6 Hz of 0.14±0.09 kPa·L −1 ·s. Comparisons with the wave-tube technique applied on two analogues indicated an overestimation by IOS. X rs,IOS and X rs,FOT were very similar, with a slightly higher resonant frequency with IOS than with FOT (mean difference±sd 1.35±3.40 Hz). R aw was only moderately correlated with R rs-FOT and R rs-IOS ; although the mean differences were small (0.04±0.14 kPa·L −1 ·s for R rs 6 ,FOT and −0.10±0.14 kPa·L −1 ·s for R rs 5 ,IOS ), IOS and FOT markedly underestimated high resistance values. In conclusion, the impulse oscillation system yields respiratory system resistance and reactance values similar, but not identical to those provided by the forced oscillation technique.
How would you decide?
Journal: JAMA (1976)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Self-confrontation by video tape. A remedial measure in teaching diagnostic evaluation
Authors: L. O. Torkelson
Journal: JAMA (1967)

Video tape recording technology has progressed to the point where it is feasible to adapt it to a host of healthscience applications. One of these is the recording of fourth-year medical students as a remedial measure in teaching diagnostic evaluation. Although no attempt has been made to evaluate the technique scientifically, preliminary impressions from both teachers and students indicate a high degree of agreement that it is a valuable, easy-to-employ procedure.
Another Family With the Li-Fraumeni Cancer Syndrome
Authors: Robert W. Miller
Journal: JAMA (1983)

<h3>To the Editor.—</h3> Four of the original families with soft-tissue tumors in children and other cancers in close relatives, especially breast cancer in young women, have recently been brought up to date by Li and Fraumeni (1982;247:2692). In 31 surviving family members, ten experienced 16 additional cancers between 1969 and 1980. We observed a family with a variation on this theme that features brain tumors (Figure). Among four children in a sibship, two experienced double-primary malignant tumors: embryonal rhabdomyosarcoma of the right paranasal region at 22 months old and osteogenic sarcoma of the midmandible (outside of the radiation field) at 14 years of age occurred in one child, and in the other child, acute lymphocytic leukemia at 17 years of age was followed two months later by the diagnosis of high-grade chondrosarcoma of the ilium. Their mother died of metastatic carcinoma of the left breast diagnosed at age 26 years.
TREATMENT OF HYPEREMESIS GRAVIDARUM BY THE DUODENAL TUBE
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Geriatric Medicine
Authors: William B. Applegate
Journal: JAMA (1997)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Accidental Hypothermia: A Common Condition
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Newer antidepressants and gabapentin for hot flashes: An individual subject pooled analysis
Authors: C. L. Loprinzi, J. A. Sloan, V. Stearns, B. Diekmann, P. J. Novotny, G. Kimmick, P. Gordon, K. J. Pandya, T. Guttuso Jr, S. Reddy
Journal: Journal of Clinical Oncology (2008)

9537 Background: Non-hormonal treatment options have been investigated as treatments for hot flashes, a major clinical problem in many women. Starting in 2000, a series of 10 individual double-blind, placebo-controlled studies involving newer antidepressants and gabapentin have evaluated these non-hormonal agents for decreasing hot flashes from a no-treatment baseline period, inclusive of all known such published trials through 2007. Methods: Individual patient data were collected. Between-study heterogeneity was tested via chi- square tests prior to a pooled analyses. The change in hot flash activity from baseline to week 4 for each agent was calculated via both weighted and unweighted approaches using the size of the study as the weight. The effect size was recalculated using an unweighted approach to test the sensitivity of the results relative to the influence of individual study sample sizes. Regression models and linear random effects were used to adjust for age, breast cancer history, and tamoxifen usage on hot flash activity. Results: Data from 1,341 patients indicated that paroxetine (2 studies), venlafaxine (1 study), fluoxetine (1 study), and sertraline (3 studies) decreased absolute hot flash scores by 41%, 33%, 13%, and 3%-18% more than did their corresponding placebo arms, respectively. As a group, the antidepressants decreased absolute hot flash scores by 26 % more than was seen with their corresponding placebo arms (P= 0.0001). The three gabapentin trials decreased absolute hot flashes by 35–38% more than did their corresponding placebo arms (P= 0.0001). Results were similar for the weighted and unweighted effect size approaches. Age, breast cancer history, and tamoxifen usage did not impact the findings. Conclusions: Newer antidepressants, as a group, and gabapentin decrease hot flashes significantly more than do placebos. There may be efficacy differences among the different antidepressants. Author Disclosure Employment or Leadership Consultant or Advisory Role Stock Ownership Honoraria Research Expert Testimony Other Remuneration Concert Pharmaceuticals, JDS Pharmaceuticals, Wyeth
Torsion of the spermatic cord in utero
Authors: R. J. Fitzpatrick
Journal: JAMA (1970)

Spermatic cord torsion was surgically treated in a 7-hour-old infant. Intrauterine onset was clearly evident. Palpation of the genitalia by the obstetrician immediately after birth and very prompt surgical intervention as recommended for the older patient is mandatory if salvage rate is to be improved. Perhaps torsion discovered at birth is already past the critical time for salvage!
Allergic alveolitis caused by home humidifiers. Unusual clinical features and electron microscopic findings
Authors: G. W. Burke
Journal: JAMA (1977)

Allergic alveolitis (hypersensitivity pneumonitis) developed in two patients who were exposed to home humidifiers contaminated by thermophilic actinomycetes. Diagnosis was difficult because severe dyspnea was chronic and not easily associated with specific environmental exposure. Furthermore, chest roentgenograms were normal for long periods despite severe physiologic abnormalities. After several years of disabling symptoms, open lung biopsy findings suggested allergic alveolitis rather than sarcoidosis because a mononuclear interstitial infiltrate overshadowed the granulomas. Also, plasma cells were prominent and there was an intense bronchiolitis. Cultures of the humidifier water grew thermophilic organisms to which the patients' sera formed precipitins. Both patients experienced notable subjective and objective improvement following removal of the contaminated appliances. The ultrastructure of alveolar macrophages and basement membranes was similar to that described in animal models, suggesting cell-mediated hypersensitivity in the patients. (<i>JAMA</i>238:2705-2708, 1977)
Abstract 2658: Does Aortic Valve Morphology Influence The Natural History Of Aortic Regurgitation?
Authors: Joan Alguersuari, Antonia Sambola, Pilar Tornos, Arturo Evangelista
Journal: Circulation (2007)

BACKROUND: The influence of the morphology of aortic valve on the natural history of aortic regurgitation (AR) is uncertain. OBJECTIVE: To assess the natural history of AR in patients with bicuspid aortic valve (BAV) comparing with tricuspid aortic valve (TAV). METHODS AND RESULTS: Ninety-five patients with asymptomatic severe chronic AR were prospectively studied. Follow-up period was 7+/- 2 years. Forty-one patients (42%) had BAV and were significantly younger than patients with TAV (39 +/- 11 vs 47 +/- 14 years, p=0.001). Mean ascending aortic diameter (AAD) was significantly larger in BAV (42 +/- 7 vs 37 +/- 5 mm, p=0.0001). Differences in AAD persisted until the end of the follow-up (47 +/- 6 vs 40 +/-5 mm, p=0.0001). The percentatge of increase in AAD was 12 +/- 5% in BAV and 8 +/- 5% in TAV with yearly increase of 0.83 mm in BAV and 0.42 mm in TAV. The changes in left ventricle diameters, mass index, wall stress, regurgitant fraction and ejection fraction were similar in BAV and TAV. Patients with BAV did not need surgery earlier due to AR than patients with TAV (4.7 +/- 2 vs 4.8 +/- 3 years). At 5 years follow-up 11 patients with BAV (27%) and 10 patients with TAV (23%) needed surgery. CONCLUSIONS: Patients with BAV are younger, had a larger AAD and a higher rate of AAD enlargement than patients with TAV. The morphology of the aortic valve (BAV vs TAV) had no infuence in the progression of AR and the impact on left ventricular function.