tbuckley/cabot-search huggingface dataset:
Commentary
Authors: L Svanstrom
Journal: British Journal of Sports Medicine (2001)

Background-Skateboarding injuries have increased with the rise in popularity of the sport, and the injury pattern can be expected to have changed with the development of both skateboard tricks and the materials used for skateboard construction.Objective-To describe the injury pattern of today.Methods-The pattern of injuries, circumstances, and severity were investigated in a study of all 139 people injured in skateboarding accidents during the period 1995-1998 inclusive and admitted to the University Hospital of Umeå.This is the only hospital in the area, serving a population of 135 000.Results-Three of the 139 injured were pedestrians hit by a skateboard rider; the rest were riders.The age range was 7-47 years (mean 16).The severity of the injuries was minor (AIS 1) to moderate (AIS 2); fractures were classified as moderate.The annual number of injuries increased during the study period.Fractures were found in 29% of the casualties, and four children had concussion.The most common fractures were of the ankle and wrist.Older patients had less severe injuries, mainly sprains and soft tissue injuries.Most children were injured while skateboarding on ramps and at arenas; only 12 (9%) were injured while skateboarding on roads.Some 37% of the injuries occurred because of a loss of balance, and 26% because of a failed trick attempt.Falls caused by surface irregularities resulted in the highest proportion of the moderate injuries.Conclusions-Skateboarding should be restricted to supervised skateboard parks, and skateboarders should be required to wear protective gear.These measures would reduce the number of skateboarders injured in motor vehicle collisions, reduce the personal injuries among skateboarders, and reduce the number of pedestrians injured in collisions with skateboarders.
Multicenter phase II study of irinotecan plus weekly bolus 5-FU and high dose l-leucovorin for patients with metastatic colorectal cancer (OGSG 0201)
Authors: H. Ishida, H. Mishima, S. Iwamoto, T. Morimoto, T. Kato, T. Tsujinaka, H. Furukawa
Journal: Journal of Clinical Oncology (2004)

3718 Background: This phase II study was undertaken to determine the efficacy of irinotecan plus weekly bolus 5-FU and high dose l-leucovorin for patients with metastasic colorectal cancer. Methods:On the basis of the results of our phase I study (Proc ASCO 22: 338, 2003), irinotecan (100 mg/m2), 5-FU (500 mg/m2), and l-LV (250 mg/m2) (Rosewell park regimen) were administered on days 1, 8, and 15, respectively, Cycles were repeated every 5 weeks. Results: Forty-five patients (median age, 64 years: males, 60%) were enrolled onto this multicenter, phase II study (Osaka Gastrointestinal Cancer Chemotherapy Study Group: OGSG protocol 0201). Objective complete response, partial response or stable disease was observed in 2.2%, 22.2% and 62.2% of patients respectively. The common grade 3 to 4 toxicities were neutropenia (31.1%), leukopenia (15.6%), anemia (6.7%), diarrhea (6.7%), anorexia (4.4%), nausea (2.2%) and vomiting (2.2%). The median relative dose intensity of irinotecan and 5-FU was 83.3% (33.3–100%) respectively. The median cycles were four. There were no deaths related to this combination therapy. Conclusions: The combination therapy of irinotecan plus weekly bolus 5-FU and high dose l-leucovorin for patients with metastatic colorectal cancer seems to be effective and well tolerated in Japan. The survival period is being assessed and updated data will be present at the meeting. No significant financial relationships to disclose.
Estrogen-progestogen combinations for contraception
Authors: R. Hertz
Journal: JAMA (1966)

The growing acceptance of various steroid compounds as contraceptive agents has been attended by extensive controversy concerning both the immediate and delayed effects of these preparations. This communication aims to identify certain questions which merit consideration and to appraise the currently available data bearing on these problems. Such a discussion is imperative because of piecemeal and inadequate treatment of these matters in the lay and scientific press. Meanwhile, the distribution of steroid compounds as contraceptives has become an accepted function of numerous public health agencies despite the lack of appropriately designed epidemiologic studies concerning many of their important potential effects. The following problems are selected for discussion because they exemplify the unmet need for more comprehensive epidemiologic analysis: (1) Will the prolonged use of steroid contraceptives affect the incidence or the pathogenesis of such malignant tumors as cancer of the breast, endometrium, or cervix? (2) Do these substances increase the
Re: Geraldine Pignot, Antoine Thiery-Vuillemin, Jochen Walz, et al. Nephrectomy After Complete Response to Immune Checkpoint Inhibitors for Metastatic Renal Cell Carcinoma: A New Surgical Challenge? Eur Urol. In press. https://doi.org/10.1016/j.eururo.2019.12.018
Authors: Nirmish Singla, Vitaly Margulis
Journal: European Urology (2020)
Saccharin—After the War
Journal: JAMA (2019)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
MILK AND TUBERCULOSIS.
Journal: JAMA (1907)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Effects of burglary on elderly people.
Journal: BMJ (1989)

We need to be wary of recommending to our colleagues in district general hospitals high tech- nology procedures that are often not available and that require skill.Eighty one years ago James Mackenzie wrote in the preface of his marvellous book3: "In routine practice it is not usually neces- sary to take graphic records.If one-is trained to make careful and minute observations by the ordinary methods, and to have these checked by graphic records, one can ultimately acquire the power of recognising the majority of movements of the circulation without graphic records."Partly out of necessity but also out of kindness to our patients we need to remember his advice.Technology has made possible most of the spectacular advances in cardiology and cardiac surgery in the past 35 years.Once we have learnt from it, however, we can often dispense with it, par- ticularly if we wish to train our successors to be good doctors and not just high technologists.
Where is the health in health system reform?
Authors: J. Fielding
Journal: JAMA (1994)

THE HEALTH system reform debate is over how to organize, deliver, and finance personal health care services. At $1 trillion, the enormity of the health care sector warrants a healthy debate about its structure and the respective roles of the public and private sectors. Erosion of middle-class health insurance coverage and an insecure economic and employment future have mobilized a broad constituency for insurance market reforms.<sup>1,2</sup>Distributive justice issues raise concern for the 40 million Americans without health benefits. Lost, however, among discussions of health security, universal coverage, and competitive markets is the unstated principal mission that any health system must serve to<i>improve</i>the health of the entire population. Legislators know that increasing public interest in health reform is attributable to the emergence of health insurance coverage as a middle-class issue.<sup>2,3</sup>An increasing proportion of the voting public has become part See also pp 1276 and 1297.
Norovirus Outbreak in an Elementary School—District of Columbia, February 2007
Journal: JAMA (2008)

On February 8, 2007, the District of Columbia Department of Health (DCDOH) was notified of an outbreak of acute gastroenteritis in an elementary school (prekindergarten through sixth grade). The school nurse reported that 27 students and two staff members had become ill during February 4--8 with nausea, vomiting, and diarrhea; because symptoms lasted <48 hours, a viral etiology was suspected. DCDOH recommended two preinvestigation interventions, which were implemented the same evening (February 8): 1) more thorough handwashing and 2) bleach cleaning of all shared environmental surfaces with a diluted (1:50 concentration) household bleach solution. This report summarizes the subsequent investigation of the outbreak, which suggested that noncleaned computer equipment (i.e., keyboards and mice) and person-to-person contact resulted in illness. To decrease disease transmission during gastroenteritis outbreaks, public health officials should emphasize good handwashing practices, exclusion of ill persons, and thorough environmental disinfection, including fomites that are shared but not commonly cleaned.
Radiation-Associated Impotence
Authors: Irwin Goldstein
Journal: JAMA (1984)

External beam pelvic irradiation in men is frequently complicated by erectile dysfunction. We tested the erectile function in 23 patients (mean age, 65 years) who received radiation therapy for prostate cancer. Fifteen patients experienced changes in erectile potency following radiotherapy. Neurological, endocrine, and vascular testing revealed abnormalities in 0, 5, and 15 of these patients, respectively. In two, arteriography revealed bilateral occlusive disease in the distal internal pudendal and penile arteries overlying the pelvic radiation field. A significant difference with cigarette smoking was found among the 15 patients whose erectile capacity decreased and the four patients whose capacity remained unchanged. Vasculogenic impotence is the most consistent organic erectile abnormality in RAI. (<i>JAMA</i>1984;251:903-910)
Antiphospholipid Antibodies
Authors: Arjun Gupta, David H. Johnson, Srikanth Nagalla
Journal: JAMA (2017)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Aortic Insufficiency
Authors: Dorothy Kunstadt
Journal: JAMA (1976)

A bizarre mechanism of aortic valve incompetence was observed when the occluder of a Braunwald-Cutter aortic valve prosthesis decreased in diameter, volume, and weight, and from time to time fell into the left ventricle. The patient's symptoms were palpitation, coughing, choking sensations, and fright. An operation disclosed a small, smooth ball with disrupted cloth on all the struts. The residual torn mesh was removed, and the ball was replaced. (<i>JAMA</i>235:2847-2848, 1976)
Custom cervical cap reentering clinical trials
Authors: K. Prupes
Journal: JAMA (1983)

"We're back at square one, but knowing a lot more." With this wry admission, Robert A. Goepp, DDS, PhD, told<i>JAMA</i>MEDICAL NEWS of a second attempt, beginning soon, to assess the contraceptive efficacy of a custom-fitted valved cervical cap that he and obstetrician-gynecologist Uwe E. Freese, MD, invented (<i>JAMA</i>[MEDICAL NEWS] 1980;243:1617). An initial National Institutes of Health (NIH)-sponsored trial, begun in November 1981, was abruptly halted the following April, plagued by an excessive number of cap dislodgements and pregnancies. The cap's checkered history began one day in 1974 at the University of Chicago Pritzker School of Medicine, where both Goepp and Freese were faculty members. Freese was lamenting the deficiencies of the older, presized cervical caps, namely, dislodgement and malodor. The obvious solution, replied Goepp, to whom custom-fitting dental appliances was second nature, was to fashion an exactly fitting cervical cap with no cul-de-sacs where cervical mucus could
SIGMUND POLLITZER (1859-1937)
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
TCTAP A-101 Efficacy of the Preoperative Assessment with Ultrasonography “Vascular Elastograph” in Endovascular Therapy
Authors: Hideyuki Takimura, Toshiya Muramatsu, Reiko Tsukahara, Yoshiaki Ito, Tsuyoshi Sakai, Hiroshi Ishimori, Keisuke Hirano, Masatsugu Nakano, Masahiro Yamawaki, Motoharu Araki, Tamon Kato, Norihiro Kobayashi, Yasunari Sakamoto, Shinsuke Mori, Masakazu Tsutsumi, Hiroya Takafuji, Takahiro Tokuda, Makino Kenji
Journal: Journal of the American College of Cardiology (2014)
Medical Economics
Journal: JAMA (1935)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
"HOPEFULLY..."
Journal: JAMA (1967)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Neoadjuvant chemotherapy (NC) in cervical cancer (CC) stage IB2, IIA and IIB: An analysis of 109 patients
Authors: C. Tosello, M. T. Laloni, F. Moura Silva, R. L. R. Costa, E. M. Fukazawa, F. Medina, J. C. G. S. Góes
Journal: Journal of Clinical Oncology (2004)

5087 Background: To evaluate the influence and the efficacy of the NC with Cisplatin (C) and Bleomycin (B) in CC stage IB2, IIA and IIB in a Brazilian single center. Methods: We verified retrospectively our experience with the C (50 mg/m2 D1-D2) and B (30 UI –D2) every 28 days for three cycles as a NC in stage IB2, IIA and IIB (FIGO) CC. All Pts (n = 109) received the NC described. After the conclusion of the NC all pts were submitted to physical exam to obtain the clinical staging and the response to the treatment. Eligible pts were then submitted to curative surgery and complementary Radiotherapy (RT) if necessary. Pathologic nodal involvement and pathologic characteristics of the tumors were evaluated after the surgical procedure. The most common toxicities and the 2 years follow-up will be reported. Results: Between December 1993 and October 2001 a total of 109 patients (ranging from 22 to 72 years old –median 43.84) were encountered in our files. Clinical staging IB2, IIA and IIB represented 70.4, 17.34 and 12.26% of the pts respectively. The clinical results were: complete response = 4.20%; partial response greater than 50% = 52.90%; partial response lesser than 50% = 12.80%; absence of response = 25.90% and progression = 4.20%. 104 pts (95.41%) were submitted to curative surgery and pathologic nodal involvement was detected in 21.10%. Squamous cells carcinomas represented 80% while adenocarcinomas 15% approximately. After a follow-up of 2 years 70.75% of the pts was free of disease while 12.10% had developed metastasis and 4% was dead. Conclusions: Our results indicate that NC in stage IB2, IIA and IIB CC with C and B offers a clinical benefit of approximately 70%. The majority of the clinical staging IIB patients (8 pts) were treated with curative surgery after NC showing the benefit of the treatment. Furthermore, our results demonstrate that C and B NC in CC are active and well tolerated and can offer a better approach to pts with locally advanced disease. However, randomized trials are necessary to confirm our results. No significant financial relationships to disclose.
Poor Britain.
Authors: N. Beale
Journal: BMJ (1992)

necessary."The decision in the House of Lords in one case states "In considering lawfulness of medical and surgical treatment given to a patient who for any reason, temporary or permanent, lacks the capacity to give or to communicate consent to treatment, it was stated to be axiomatic that treatment which is necessary to preserve life, health or well being of the patient may lawfully be given without consent."In emergency treatment, where decisions need to be taken quickly, the legal position may be far from clear cut and medical staff may be open to prosecution for assault under common law.Most medical staff have little or no appreciation of the lack of clarity in the legal position governing the treatment of patients against their wishes in emergencies.The case concerning the Jehovah's Witness raised "for the first time in English courts the question of whether an adult has the constitutional right to die."2The patient described here made a complete recovery.Several weeks later he came to the outpatients department without an appointment to thank us profusely for having saved his life.The laws governing the treatment of drug overdose should be clarified to protect doctors who other- wise may face legal proceedings for acting in good faith and with compassion.