tbuckley/cabot-search huggingface dataset:
The Cover
Authors: M.Therese Southgate
Journal: JAMA (1988)

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RADIOACTIVE PHARMACEUTICALS
Journal: JAMA (1966)

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Discussion
Journal: British Journal of Sports Medicine (1976)

SCHOTMAN: I am surprised at the number of positives you have now found.BLAKE: This is in a post-race situation where we do have the availability of hydrolysing our samples.About 16% of our positive drugs, particularly the phenothiazine tranquillisers, synthetic narcotics such as pentazocine do require a hydrolysis procedure.About 16% of these drugs are found as hydrolysed products, the others can be determined equally well in either blood or urine by direct extraction.SCHOTMAN: Last year in Oslo there was an international congress of Jockey Clubs.On pre-race testing, someone reported that in the United States they had done about 20,000 pre-race samples and only one was positive, but it was a preventative measure.There was a great difference at the various racetracks, one is post-race testing, another is pre-race.You have had many more positive results.
Omission, a Non
Journal: JAMA (1972)

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From the Centers for Disease Control and Prevention. Recommendations for HIV testing services for inpatients and outpatients in acute-care hospital settings
Journal: JAMA (1993)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Trichinosis masquerading as a penicillin allergy
Authors: P. Altus
Journal: JAMA (1980)

TRICHINOSIS is a parasitic infection most frequently involving striated muscle. Inadequately cooked pork is the most common source of acquisition, although wild animal flesh has been implicated in several cases.<sup>1</sup>Adulteration of "safe" meats with pork by common utensils or meat grinders contributes to the prevalence of the infection. The incidence of this disease has been gradually declining, and it is presently very infrequently encountered in this country. As a result, many physicians may not be aware of the diagnosis until late in the course of the disease. In 1976, there were 96 cases reported to the Center for Disease Control (CDC), only one of which occurred in Florida.<sup>2</sup>We describe here a patient demonstrating vague symptoms and laboratory data that could have been misleading. <h3>Report of a Case</h3> A 27-year-old man came to the Tampa (Fla) General Hospital emergency room complaining of fever, chills, and myalgias. The
TRENCH FEVER
Journal: JAMA (1918)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Physicochemical and bacteriological analysis of the contents of occluded biliary endoprostheses
Authors: C Moesch
Journal: Hepatology (1991)

The deposits obstructing 12 biliary endoprostheses were examined by scanning electron microscopy and analyzed quantitatively by Fourier transform infrared spectroscopy. Calcium palmitate and bilirubinate associated with proteins were found in all the deposits. Apart from the small amount of cholesterol, this composition closely resembled that of brown pigment gallstones and suggested an infectious cause. Facultative aero-anaerobic organisms were found on bacteriological investigation. β-Glucuronidase activity was only detected in one sample, suggesting that the calcium bilirubinate may have been formed through tissue glucuronidases. In our study, deposit formation was thought to have been caused by the action of bacterial phospholipases (although not measured) rather than β-glucuronidases. (HEPATOLOGY 1991;14:1142–1146.)
Effectiveness of 8 weeks of glecaprevir/pibrentasvir in treatment-naive hepatitis C patients with liver cirrhosis: results from the real-world Spanish Hepa-C registry
Authors: Juan Turnés, Manuel Hernandez-Guerra, Raquel Souto Rodríguez, Inmaculada Fernández, Jose A. Carrión, Beatriz de Cuenca Morón, Juan Manuel Pascasio, Jose María Moreno Planas, José Juan Moreno, Pau Bellot, Manuel Delgado, Javier Salmerón, Zoe Mariño, Jose Miguel Rosales Zabal, Francisco Javier Garcia-Samaniego Rey, Rosa Morillas, Moises Diago, Javier Crespo, Jesús González Santiago, Beatriz Mateos Muñoz, Xavier Torras, Esther Badia-Aranda, Lucia Bonet, Fernando Menéndez, Vanesa Bernal Monterde, Paqui Márquez Rodríguez, Juan Arenas, Martín Prieto, Santiago Pérez Cachafeiro
Journal: Journal of Hepatology (2020)
Elevated FGF23 Levels Are Associated with Impaired Calcium-Mediated Suppression of PTH in ESRD
Authors: James B. Wetmore, Peter Santos, Jonathan D. Mahnken, Ron Krebill, Rochelle Menard, Hema Gutta, L. Darryl Quarles
Journal: Endocrine Reviews (2010)

The positive association of elevated fibroblast growth factor-23 (FGF23) with PTH levels in the setting of secondary hyperparathyroidism is paradoxical to the purported effects of FGF23 to suppress PTH secretion. We used dynamic calcium-mediated suppression of PTH levels in hemodialysis (HD) patients to determine the relationship between FGF23 levels and parathyroid gland function. HD patients with elevated PTH were washed out of vitamin D analogs and/or calcimimetics and then exposed them to a high-calcium dialysate bath designed to suppress PTH. The study was conducted at an outpatient HD unit of an academic medical center. Eighteen maintenance HD patients with elevated PTH levels participated in the study. Ionized calcium (iCa), PTH, and FGF23 levels were measured during HD. The slope of the relationship between iCa and PTH (a marker of parathyroid gland mass) and the iCa level required for a 50% reduction in PTH were determined, and the association of these with FGF23 levels was determined. Increased baseline log FGF23 levels were associated with putative alterations in gland mass as estimated by significantly shallower slopes of the iCa/PTH suppression curves (P = 0.0004), but there was no association between FGF23 and calcium sensing as measured by ionized Ca associated with a 50% suppression of PTH (P = 0.38). FGF23 levels decreased significantly during HD, but this change was not correlated with decrements in either renal phosphate or PTH. High FGF23 levels may be a marker for parathyroid gland hyperplasia in HD patients. Acute reductions in neither PTH nor renal phosphate during dialysis correlated with PTH suppression.
ABSTRACTS
Authors: R. E. SMITH
Journal: Circulation (1966)

The case history reported in this article is that of a 3-year-old girl with chronic lead poisoning associated with myocarditis.The patient presented with a clinical picture of lead encephalopathy and then developed signs of heart failure which was finally attributed to myocarditis.The rapid reversal of the clinical and electrocardiographic signs of myocarditis during treatment of the lead poisoning with sodium calciumedetate sug- gested that the lead was directly responsible for the cardiac changes.The author concluded that all patients with chronic lead poisoning should have a careful cardiac evaluation in order to be certain that direct myocardial damage has not occurred.Strong and vigorous therapy is indi- cated since the myocardial impairment appears to be completely reversible.
Meetings of Medical Interest
Journal: JAMA (1997)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Ethical Issues in Research in Complementary and Alternative Medicine
Authors: Ted J Kaptchuk, Anthony Lembo
Journal: JAMA (2004)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
ON THE BACTERICIDAL FUNCTION OF THE LIVER AND THE ETIOLOGY OF PROGRESSIVE HEPATIC CIRRHOSIS.
Journal: JAMA (1898)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Asthma
Authors: Mark J. Ellenbogen
Journal: JAMA (1978)

This is an extremely well-written book that concisely reviews modern medical concepts of asthma. The authors are able to skillfully explain the scientific basis for asthma without being didactic. Controversial and varied ideas are presented in a lucid manner. Most importantly for the practitioner, the authors bring clinical meaning to basic science. All of the chapters may be read individually, but when taken as a whole, the book gives a good overview of a complex disease process. The section on physiology provides an exceptionally clear and concise explanation of lung mechanics. Normal airway physiology is reviewed, and pathophysiology is well correlated with pulmonary function testing. Each test, ranging from simple spirometry to dynamic compliance studies, is accurately described and remarkably up to date. In addition, the practical approach to pulmonary function testing, offered here, includes many pitfalls, knowledge of which is useful in testing patients. As its greatest strength, this
Clinical Significance of Free Circulating CD33 in Patients with Acute Myeloid Leukemia and Myelodysplastic Syndrome.
Authors: Menna Hodge, Francis Giles, Adam Abdool, Susan O’Brien, Michael Keating, Iman Jilani, Zeev Estrov, Elihu Estey, Hagop Kantarjian, Maher Albitar
Journal: Blood (2006)
<i>Announcement</i>: National Chronic Obstructive Pulmonary Disease Awareness Month — November 2017
Journal: MMWR Morbidity and Mortality Weekly Report (2017)

World Pneumonia Day, observed on November 12 each year, aims to highlight the huge toll pneumonia takes on children and adults worldwide.In 2015, an estimated 2.7 million persons died from respiratory infections, including 700,000-920,000 children aged <5 years (1,2).Streptococcus pneumoniae and Haemophilus influenzae type b bacteria cause most of these deaths; however, viruses, including influenza and respiratory syncytial virus, also have a considerable impact (1).Multiple vaccines are available to help prevent pneumonia, including Haemophilus influenzae type b, influenza, measles, pertussis, pneumococcal, and varicella vaccines.Expanding the use of the pneumococcal conjugate vaccine in childhood immunization programs around the world has reduced disease incidence in recent years, particularly among children aged <5 years (3).Despite progress globally in reducing the incidence of pneumonia, recent U.S. outbreaks serve as a reminder of the importance of maintaining high vaccination coverage to prevent pneumonia.For example, as of August 25, 2017, more than a quarter (28%) of 79 measles patients in a Minnesota community with low measles-mumps-rubella vaccination coverage required hospitalization, primarily for treatment of dehydration or pneumonia (4).In addition to vaccination, other strategies have been proven to help prevent pneumonia.Adherence to antibiotic use guidelines reduces the development of antibiotic resistance among pneumonia-causing organisms.In addition, access to tobacco cessation programs (5), decreased exposure to secondhand smoke (5) and reduction in indoor air pollution from biomass smoke in developing countries (6) are important pneumonia prevention strategies that can save lives.Continued efforts to improve access to appropriate treatment for those who get pneumonia are also needed.Information about World Pneumonia Day, including the 2017 Pneumonia and Diarrhea Progress Report, is available at http://stoppneumonia.org/.
British Society for Paediatric Dermatology
Authors: S Bakshi, A Karim, S Handa, D De, R Mahajan, S El-Heis, S D'angelo, E Curtis, E Healy, S Crozier, H Inskip, C Cooper, N Harvey, K Godfrey
Journal: British Journal of Dermatology (2020)

The aim of this study was to compare the effectiveness and safety of oral vitamin D vs. low-dose acitretin in the treatment of nonsyndromic congenital ichthyosis and to assess the effect of treatment on the mRNA expression of RAR-related orphan receptor gamma t (RORct) and interleukin (IL)-17 in peripheral blood mononuclear cells in the two groups.Twenty-seven consecutive patients with congenital nonsyndromic ichthyosis (excluding common ichthyosis) were recruited and randomized into two study groups.Group A received oral vitamin D (2000 IU daily) plus placebo similar to oral acitretin, while group B received low-dose oral acitretin 0.5 mg kg -1 daily (maximum 25 mg daily) plus placebo similar to oral vitamin D tablets for 24 weeks.The clinical severity was assessed by Visual Index for Ichthyosis Severity (VIIS), Ichthyosis Area Severity Index (IASI) and the Ichthyosis Quality of Life Index-32 (IQoL-32) at baseline, 12 weeks and 24 weeks.The mRNA expression of RORct and IL-17 in peripheral blood mononuclear cells was also assessed by reverse transcriptast polymerase chain reaction in the two groups at baseline and at 24 weeks post-treatment.Both group A and group B showed an improvement in clinical severity.Group A showed a statistically significant decrease in VIIS (P = 0.049) and IASI (P = 0.029) at 12 weeks, but this response was not maintained to 24 weeks (P = 0.096 and P = 0.074 for VIIS and IASI, respectively).The IQoL-32 improved significantly from baseline to 12 weeks (P = 0.003) and 24 weeks (P = 0.003).There was a statistically significant decrease in the relative mRNA expression of RORct (P = 0.007) and IL-17 (P < 0.001) at 24 weeks.Group B did not show a significant decrease in the VIIS and IASI at 12 weeks, but the decrease in IASI at 24 weeks was statistically significant (P = 0.019).IQoL-32 improved significantly from baseline to 12 weeks (P < 0.001) and 24 weeks (P = 0.003).There was a decrease in relative mRNA expression of RORct (P = 0.73) and IL-17 (P = 0.3) in group B, although it was nonsignificant.There was no statistically significant difference between the two treatment arms in terms of VIIS (P = 0.53), IASI (P = 0.22) and IQol-32 (P = 0.08) at 12-and 24-weeks post-treatment.No serious adverse events were observed in any treatment arm.We conclude that oral vitamin D (2000 IU daily) may be used as an alternative therapy to oral acitretin in the treatment of congenital nonsyndromic ichthyosis as it leads to comparable clinical effectiveness.The therapeutic effect of vitamin D is mediated by reducing the expression of RORct and IL-17.