tbuckley/cabot-search huggingface dataset:
Allergy
Authors: Walter S. Burrage, J. Evarts Greene, Leo B. Burgin, Irving H. Itkin, Harold S. Novey, Joseph Engler, John W. Irwin
Journal: New England Journal of Medicine (1956)

The SteroidsThe introduction and increasingly widespread use of ACTH and the adrenocortical steroids have provided a fascinating and provocative development in clinical allergy. The influence of these agents on allergic symptomatology has called increasing attention to the allergic diseases, not only by the laity but also by various branches of the medical profession. For example, the patient, who has been on prolonged hormonal therapy and who is facing an operation, is a problem for the surgeon as well as the internist.The choice of available preparations is wide and is very likely to increase. ACTH is available for intravenous . . .
Infectious complications with plasmapheresis in rapidly progressive glomerulonephritis
Authors: E. J. Wing
Journal: JAMA (1980)

We recently used plasmapheresis to treat eight patients with rapidly progressive glomerulonephritis. Life-threatening infections developed in five patients, three of which were caused by opportunistic pathogens. In contrast, only two infections occurred in 21 patients with similar renal disease treated with immunosuppressive drugs but not with plasmapheresis. Although infectious complications of plasmapheresis therapy have not been emphasized previously, our experience, coupled with that of previous reports, suggests that serious infections will develop in one third of patients undergoing plasmapheresis for renal disease. Plasmapheresis should be used with caution in patients with rapidly progressive glomerulonephritis. (<i>JAMA</i>244:2423-2426, 1980)
Ligation of the Inferior Vena Cava In Early Pregnancy
Authors: R. D. Sutherland
Journal: JAMA (1968)

<h3>To the Editor:—</h3> The possibility of morbidity and mortality due to pulmonary thromboembolism is a real one, even in young adults.<sup>1,2</sup>We have recently encountered a case in which ligation of the inferior vena cava was performed early in pregnancy for pulmonary thromboembolism which occurred bilaterally. Ligation of the inferior vena cava during pregnancy has been only rarely reported.<sup>3,4</sup> <h3>Report of a Case:—</h3> A 32-year-old woman was hospitalized on July 16, 1966, because of pleuritic pain in the right upper quadrant of the abdomen of several hours' duration. There was also some nausea and vomiting. The referring physician suspected cholecystitis. The patient's last menstrual period had been May 14, 1966. The patient was in the tenth week of her sixth pregnancy. The first pregnancy was complicated by toxemia at term. The next three pregnancies were uncomplicated. The fifth terminated in spontaneous complete abortion at approximately four months. She
IMPERATIVE NEED OF UNION OF THE MEDICAL PROFESSION AND THE HEALTH AUTHORITIES
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Small Cell Lung Cancer
Authors: _ _
Journal: Journal of the National Comprehensive Cancer Network (2008)

Small cell lung cancer (SCLC) accounts for 15% of lung cancers. Nearly all cases of SCLC are attributable to cigarette smoking, and the remaining cases are presumably caused by environmental or genetic factors. Compared with non-small cell lung cancer, SCLC generally has a more rapid doubling time, a higher growth fraction, and earlier development of widespread metastases. SCLC is highly sensitive to initial chemotherapy and radiotherapy, but most patients eventually die from recurrent disease. These guidelines detail the management of SCLC from initial diagnosis and staging through treatment, and include information on supportive and palliative care. Important updates to the 2008 version include refined categories for performance status and the addition of topotecan as an option for patients who experience relapse. For the most recent version of the guidelines, please visit NCCN.org
Echinococcus Cyst
Authors: N. Candreviotis
Journal: JAMA (1961)

<h3>To the Editor:—</h3> I have had the opportunity recently to make an observation which, I think, will be of some interest for your readers. Needle biopsy of the liver has been proved a very helpful method for the diagnosis of the liver diseases, such as acute or chronic hepatitis, cirrhosis, carcinoma, various types of icterus, lupoid hepatitis, and other damage of the liver parenchyma. However, as the present experience shows, other pathologic conditions of the liver must also be taken into consideration when a needle biopsy of the organ is performed. This experience is of special significance when the needle biopsy is carried out on persons living in or coming from countries in which such parasitic diseases as amebiasis or hydatid disease occur frequently. A 29-year-old woman was admitted to the hospital because there was a suspicion of acute lupus erythematosus. Her temperature had increased, and L.E. cells were found
Aortic insufficiency with mild ankylosing spondylitis in black men
Authors: W. H. Eversmeyer
Journal: JAMA (1978)

Two black male patients with aortic insufficiency were later found to have mild, asymptomatic ankylosing spondylitis, evident from roentgenograms and from the presence of HLA-B27 antigen. The two cases emphasize that even "subclinical" ankylosing spondylitis may have aortic insufficiency, and that the uncommon occurrence of ankylosing spondylitis in black patients may also be associated with this extra-articular manifestation. (<i>JAMA</i>240:2652-2653, 1978)
POCK DISEASES
Authors: E. Paschen
Journal: BMJ (1932)

<h3>ABSTRACT</h3> <h3>Objectives</h3> We have developed a deep learning model that provides predictions of the COVID-19 related number of cases and mortality in the upcoming 5 weeks and simulates the effect of policy changes targeting COVID-19 spread. <h3>Methods</h3> We developed a Deep Recurrent Reinforced Learning (DRRL) based model. The data used to train the DRRL model was based on various available datasets that have the potential to influence the trend in the number of COVID-19 cases and mortality. Analyses were performed based on the simulation of policy changes targeting COVID-19 spread, and the geographical representation of these effects. <h3>Results</h3> Model predictions of the number of cases and mortality of COVID-19 in the upcoming 5 weeks closely matched the actual values. Local lockdown with social distancing (LD_SD) was found to be ineffective compared to national lockdown. The ranking of effectiveness of supplementary measures for LD_SD were found to be consistent across national hotspots and local areas. Measure effectiveness were ranked from most effective to least effective: 1) full lockdown; 2) LD_SD with international travel −50%; 3) LD_SD with 100% quarantine; 4) LD_SD with closing school −50%; 5) LD_SD with closing pubs −50%. There were negligible differences observed between LD_SD, LD_SD with −50% food &amp; Accommodation and LD_SD with −50% Retail. <h3>Conclusions</h3> The second national lockdown should be followed by measures which are more effective than LD_SD alone. Our model suggests the importance of restrictions on international travel and travel quarantines, thus suggesting that follow-up policies should consist of the combination of LD_SD and a reduction in the number of open airports within close proximity of the hotspot regions. Stricter measures should be placed in terms travel quarantine to increase the impact of this measure. It is also recommended that restrictions should be placed on the number of schools and pubs open. <b>Strengths and limitations of this study</b> -The proposed Deep Recurrent Reinforced Learning (DRRL)-based model takes into account of both relationships of variables across local authorities and across time, using ideas from reinforcement learning to improve predictions. -Whilst, predicting the geographical trend in COVID-19 cases based on the simulation of different measures in the UK at both the national and local levels in the UK has proved challenging, this study has provided a methodology by which useful predictions and simulations can be obtained. -The Office for National Statistics only released data on UK international travel up to March 2019 at the time of this study, and therefore this study used the amount of UK tourists in Spain as a reference variable for understanding the effect of international travel on COVID-19 spread.
Die akuten Zivilisationsseuchen: Masern, Pocken, Keuchhusten, Scharlach, Diphtherie, epidemische Kinderlahme. Ihre Epidemiologie und Bekämpfung
Journal: JAMA (1934)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Biological monitoring of polycyclic aromatic hydrocarbon exposure in a highly polluted area of Poland.
Authors: S Ovrebø, P E Fjeldstad, E Grzybowska, E H Kure, M Chorazy, A Haugen
Journal: Environmental Health Perspectives (1995)

Air pollution in Poland and particularly in Silesia is among the worst in Europe. Many coal mines and coke oven plants are located in this area, representing a major source of carcinogenic polycyclic aromatic hydrocarbons (PAHs). We quantitated the PAH exposure level in air samples using personal sampling devices, collected urine samples from the same individuals, and measured 1-hydroxypyrene with high performance liquid chromatography. Samples were collected twice, once in February and once in September. Mean PAH level of samples collected at three different coke oven plants varied from 2.3 micrograms/m3 to 12.3 micrograms/m3; the lowest mean was in September. Mean levels of 0.15 micrograms/m3 (September) and 0.44 micrograms/m3 (February) were noted for the environmentally exposed group. Mean urinary 1-hydroxypyrene varied from 2.45 to 13.48 mumol/mol creatinine at the three coke oven plants. The corresponding variation between the three different environmentally exposed groups in Silesia was 0.41-1.54 mumol/mol creatinine. In the nonindustrialized area, the mean varied from 0.20 to 0.14 mumol/mol creatinine. Seasonal variation was found both at the coke oven plants and in the environmental exposed groups in Silesia. Both PAH levels and 1-hydroxypyrene varied seasonally among coke oven workers and the environmentally exposed group. Our study shows that PAH exposure in the industrialized area of Silesia is high compared to levels in Western Europe. 1-Hydroxypyrene excretion in environmentally exposed individuals in Poland is among the highest in Europe.
Lead Effects on Postural Balance of Children
Authors: A. Bhattacharya, R. Shukla, R. L. Bornschein, K. N. Dietrich, R. Keith
Journal: Environmental Health Perspectives (1990)

The postural sway responses of 63 children with a mean age of 5.74 years were quantified with a Force Platform technique. The average maximum (max) blood lead (PbB) of these children during the first 5 years of life was 20.7 micrograms/dL (range 9.2 to 32.5). The backward stepwise regression analysis for sway area response during the eyes-closed, no-foam test with all the covariates and confounders and the PbB parameters showed a significant relationship with peak or max PbB during the second year of life. These results are consistent with our previous study with a smaller group of children. The data have been analyzed to provide some insight into the role of various afferent for the maintenance of postural balance. The results suggests a hypothesis that if the max PbB had caused some level of impairment in the functional capacities or interconnectivity of the vestibular and/or proprioception systems at 2 years of age, then it is reasonable to assume that the redundancy in the postural afferent systems would naturally adapt to rely more on the remaining intact afferent system (in this case, vision).
CONGENITAL PORPHYRINURIA
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Identification of neoantigens as potential vaccines in hepatocellular carcinoma
Authors: David Reparaz, Maria Ruiz, Diana Llopiz, Leyre Silva, Enric Vercher, Ibon Tamayo, Sandra Hervás-Stubbs, Juan J. Lasarte, Mercedes Iñarrairaegui, Luigi Buonaguro, Maria Tagliamonte, Angela Mauriello, Beatrice Cavalluzzo, Bruno Sangro, Pablo Sarobe
Journal: Journal of Hepatology (2020)
ALCOHOLIC LIQUORS IN PRESCRIPTION.
Journal: JAMA (1900)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Substance Abuse
Journal: JAMA (2000)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Ventilation of Public Buildings
Journal: BMJ (1861)

The renewal of air in bniltiings is oiily reridcred neccssary by the vitiation resulting from the reipiration and exlialations of the occupants, and by tlie accuiQulation of the products of combustion from artificial lighting ; and tlie writer has been led by his own observations and the consideration of the results obtained by others to the following conclusions as t o the principles on which the ventilation of buildings should be based :- First-Ventilation consists in getting rid of all vitiated air and replacing it by fresh air.Xeco)dly-The principal object of ventilation is to get rid at once of all vitiated air.It ought to be removed in general from the point nearest to the place where the vitiation takes place, in order to prevent any further diffusion into the room ; and on the contrary fresh air ought to be introduced at the point furthest removed from the occupants of the room.Thirdly-The different arrangements that proceed by Xucfion, when well proportioned and well carried out, are more effectual than those which depend exclusively on blowing in the fresh air, as the latter do not in every instance and a t all times ensure the vitiated air being uniformly and continuously expelled.Fourthly-The quantity of fresh air required, whatever may be the height from which it has to be drawn, and whatever the quantity, can be obtained by suction alone, and without the aid of any blowing apparatus, by giving to the inlet openings for the fresh air sufficiently large climensions, and by suitable arrangement.F$tthly--Suction can easily be obtained either by means of the ordinary open fireplaces with chimneys or similar heating apparatus, or by nieans of special fireplaces placed at the bottom of the
Thursday, November 3, 1983
Authors: Robert Ritch, Max Forbes, New York, John Hetherington, San Francisco, Raymond Harrison, Steven Podos, P Diswssion, Edward Cotlier, Marshall Parks, William Scott, Helen Hittner, Arnold Rudolph, Frank Kretzer, A Diswssion, Arthur Rosenbaum, Los Angeles, Donald Mousel, John Flynn, Bay Shore, Retrolental Fibroplasia, Zane Pollard, Burton Kushner, Steve Charles, John Merritt
Journal: Ophthalmology (1983)
Omission of Funding/Support and Role of the Sponsor Acknowledgments and Disclaimer
Authors: Stephen Jan, Gillian Sanders
Journal: JAMA (2017)

Joshua L. Denson, MD; Ashley Jensen, MPA; Harry S. Saag, MD; Binhuan Wang, PhD; Yixin Fang, PhD; Leora I. Horwitz, MD, MHS; Laura Evans, MD, MSc; Scott E. Sherman, MD, MPH
Ethical aspects of human experimentation in health services research
Authors: A. Brett
Journal: JAMA (1991)

OVER the past several decades, ethical issues in human experimentation have received increasing attention in the medical literature. Most of this literature presumes a fairly standard conception of modern medical research, ie, the application of a therapeutic intervention to a group of persons with a specific diagnosis. Prototypic examples include comparisons of two drugs, or drug and placebo, for specific diagnostic entities such as cancer. For lack of better terminology, we will refer to these studies collectively as<i>conventional research</i>. In contrast, the organizational, procedural, and economic aspects of health care provision have themselves become the focus of an enlarging body of research, termed<i>health services research</i>. Until recently, these studies were characterized primarily by either retrospective data collection or concurrent observation without experimental intervention. However, in an attempt to achieve greater scientific rigor, health services research has increasingly included prospective interventions involving human subjects. The scope of this research
Osteogenesis Imperfecta
Authors: Harvey A. Rosenstock
Journal: JAMA (1968)

<h3>To the Editor:—</h3> Recently, I treated a 4-year-old white boy for a fracture of the distal tibia. The patient had blue sclerae and a history of multiple fractures associated with trivial trauma. Two of the patient's three siblings demonstrate blue sclerae or unusual tendency to sustaining fractures. His 26-year-old mother suffered repeated fractures of the extremities and clavicles as a child, and also has blue sclerae. The 12-year-old maternal uncle has blue sclerae, and has experienced frequent dislocations of the right shoulder as well as extremity fractures. A similar history can be traced to the maternal grandmother who demonstrated the cardinal signs of blue sclerae and multiple fractures from trivial insults. While this pattern of inheritance seems to exemplify the classic descriptions of osteogenesis imperfecta with its autosomal dominant, there is curiously enough a concomitant familial history of carcinoma which can be traced back to the great grandmother of this