tbuckley/cabot-search huggingface dataset:
The Respiratory System
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Discussion of Tanaka's Paper
Authors: Chikio Hayashi
Journal: Environmental Health Perspectives (1979)

The theory of quantification is a method of statistical data analysis of categorical data. In other words, this is a kind of data theory and is closely related to optimum scaling method. This method has been mainly developed by Guttman in Israel and Hayashi in Japan. The multidimensional scaling method, which has been recently developed, is considered to be a continuation of the theory of quantification. Tanaka discussed mathematically some of Hayashi's methods of quantification. The present paper, gives an overview of the methods developed by him and other closely related methods and gives the orientation of those methods introduced by Tanaka. Then, as an illustration of exploratory categorical data analysis, the experimental data of Grizzle are analyzed by using the second method of quantification. The data structure is shown heuristically as a spatial configuration of factors in two-dimensional Euclidean space.
Use of Recombinant Activated Factor VII in Severe Post-Partum Haemorrhage: Data From the Italian Registry. A Multicentric Observational Retrospective Study.
Authors: Giovanni Barillari, Maria Grazia Frigo, Maddalena Casarotto, Antonio Farnia, Barbara Massè, Roberto Wetzl, Andrea Bianchin, Andras Rabi, Paolo Malcarne, Samantha Pasca, Enrico Bigotto, Francesco Dentali
Journal: Blood (2009)
THE SCARCITY OF PHYSICIANS IN RURAL DISTRICTS
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 464: Membrane Microparticles From Ischemic Muscle Induce In Vitro Progenitor Cells Differentiation And In Vivo Neovascularization.
Authors: Aurelie S Leroyer, Teni G Ebrahimian, Jose Vilar, Bernard I Levy, Alain Tedgui, Chantal M Boulanger, Jean-Sebastien Silvestre
Journal: Circulation (2007)

Postischemic neovascularization is mediated, at least in part, by the homing of progenitor cells to sites of injury and their differentiation into endothelial cells (EC). However, the mechanisms of in situ progenitor differentiation remain for the most part unknown. We hypothesized that miproparticles (MPs) released following ischemia-induced cell activation or apoptosis are the endogenous signal of postischemic vasculogenesis. MPs were detected by electron microscopy as vesicles of 0.1 to 1 μm in diameter in mice ischemic hindlimb muscle, 48hrs after unilateral femoral artery ligation. After isolation by sequential centrifugations, flow cytometry analyses showed that AnnexinV+ MPs concentration in ischemic calf was 3.5-fold higher than in control muscle (1392±406 vs. 394±180 AnnV+MPs/mg, p&lt;0.005) and mainly originated from endothelial cells (47% of MPs are CD144+). MPs isolated from ischemic muscles induced a more potent in vitro bone marrow-mononuclear cells (BM-MNC) differentiation into EPC, than those isolated from control muscle (6.1±1.0% vs. 3.5±0.7% Dil-LDL/BS1lectin+ cells/field, p&lt;0.05). Moreover, MPs isolated from GFP+ ischemic muscles colocalized with differentiated BM-MNC. MPs isolated from atherosclerotic plaque were uneffective whereas those isolated from apoptotic or IL-1 activated EC also promoted BM-MNC differentiation. Interestingly, MPs from ischemic muscles produced more reactive oxygen species and expressed significantly higher levels of NADPH oxidase p47 (6 fold ; p&lt;0.05) and p67 subunits (16 fold ; p&lt;0.005) than those from control, whereas gp91 subunit expression was unchanged. The MPs-induced BM-MNC differentiation was reduced by two fold with MPs isolated from gp91-deficient mice (p&lt;0.05). MPs effect on post-ischemic vasculogenesis and revascularization was examined in the ischemic hindlimb model. MPs isolated from ischemic muscles were injected into ischemic legs in parallel with venous injection of BM-MNC. MPs increased the pro-angiogenic effect of BM-MNC transplantation and this effect was blunted with MPs from gp91−/− mice. These results demonstrate that MPs produced after tissue ischemia stimulate progenitor cell differentiation and subsequently promote postnatal neovascularization.
Epitomes
Authors: John Archer
Journal: JAMA (1975)

In our current Journal style, the possessive case is not used in eponymic diseases and syndromes. For example, Baron von Münchausen did not<i>own</i>a syndrome, even though his name is associated with one: thus, we write "Münchausen syndrome," not "Münchausen's syndrome." Since Dr Cushing did not actually<i>have</i>the disease he described, we merely write "Cushing disease." Nevertheless, John C. Ling, MD, of Santa Monica, Calif, perceptively notes at least one incongruity stemming from this practice. Without the added apostrophe, only the capital letter G prevents the unwary from erroneously associating Graves disease with a cemetery. In contemplating the first reference of one of my recent editorials (233:273, 1975), readers may wonder whetherThe Journalis sometimes printed backward. The pagination was given as 1397-1388; it should have been 1397-1398. This is particularly embarrassing to me, as not long ago I expressed annoyance with those authors who cite references
MEDICINE AS APPLIED SCIENCE.
Journal: JAMA (2004)

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The TLNO/TLCO ratio in pulmonary function test interpretation
Authors: J. M. B. Hughes, I. van der Lee
Journal: European Respiratory Journal (2013)

We are grateful to C. Borland for his comments on our review of the TLNO/TLCO ratio (the ratio of the transfer factor of the lung for nitric oxide versus carbon monoxide) [1] and its clinical applications.Undoubtedly, TLNO, on its own, has a role to play in accessing alveolar function in terms of the membrane diffusing capacity, DM.The calculation of pulmonary capillary volume (Vc), on the other hand, requires a value for HblCO, the specific conductance of blood for carbon monoxide, and there is some doubt about its correct value.The TLNO/TLCO ratio does not require knowledge of HblCO.An important difference between TLNO and TLCO is that TLNO is not affected by changes in alveolar oxygen tension (PAO 2 ).Thus, as Borland points out, the TLNO/TLCO ratio will fall if mean PAO 2 falls because of its dependence on the DMCO/HblCO?Vc ratio and the increase in the value of HblCO.But, with the standard single breath technique, with a maximal inspiration and subsequent breath hold, there is not likely to be much variation in PAO 2 in those units ''accessible'' to the inspired test gas, whose oxygen fraction is between 0.18 and 0.21 depending on the test gas composition.In routine lung function no corrections have been proposed for PAO 2 inhomogeneity in the single breath TLCO test.C. Borland argues that units with a high alveolar ventilation to perfusion (V9A/Q9) ratio have a high DM/Vc since pulmonary capillary blood flow (and presumably capillary volume) is low in relation to alveolar surface area and volume, and this will increase the TLNO/TLCO ratio.Because of its dependence on DMCO/ HblCO?Vc, the TLNO/TLCO ratio will be further increased in high V9A/Q9 units by the rise in PAO 2 and fall in HblCO; thus, a rise in TLNO/TLCO could be a marker for pathological processes involving the pulmonary circulation, including emphysema.We thank C. Borland for pointing this out.But, because of the nature of the single breath test, the rise in DM/Vc is likely to be more important than the fall in HblCO.The converse, that low V9A/Q9 (poorly ventilated but overperfused) regions will have a low DM/Vc ratio seems less likely, since V9A/Q9 and DM/Vc ratios are not directly related.V9A/Q9 depends on the ratio of flow rates, measured during tidal breathing; DM/Vc ratios, on the other hand, measured at full inflation during a breath hold, reflect, more or less, the ratio of alveolar membrane to capillary and red cell surface areas.As we point out in our review [1], this surface area ratio decreases as lung expansion declines (equivalent to a fall in the ratio of transfer coefficients for NO versus CO) and is the reason for the fall in TLNO/TLCO in extrapulmonary restriction.Finally, in cases of severe anaemia with very low haemoglobin levels, we take C. Borland's point that TLNO may be reduced.
The generalist function in medicine
Authors: E. D. Pellegrino
Journal: JAMA (1966)

I am sincerely grateful for the privilege of presenting the first annual American Academy of General Practice (AAGP) lecture and of expressing my convictions on the matter of general medicine— a matter of increasing moment for profession and public alike. I am of the firm conviction that the generalist function is an urgent need of present and future society. I am genuinely concerned about its gradual attenuation even in such broad fields as medicine and pediatrics, and I am convinced that for its refurbishment it must be firmly based in the medical school and the university. We have here one of a growing number of issues in which medical schools and practitioners must confront a public need cooperatively, if they are to meet current social responsibilities. There is much public anxiety that the maximum of new knowledge is not now easily available to all in their own communities. This anxiety
Cervical stabilization-traction board. A new device for immediate stabilization of the injured cervical spine
Authors: D. J. Prolo
Journal: JAMA (1973)

The cervical stabilization-traction board is a device for easy, immediate, immobilization of the injured cervical spine at the accident site. The patient's trunk is fixed to a rigid board by straps that do not encumber thoracic or abdominal structures. Movable blocks to which is secured a halter sling stabilize and distract head and neck in the position. These structures are found in all age groups. Roentgenograms may be taken with the device in place. No secondary transfers are necessary until definitive therapy is instituted.
Childhood Lead Poisoning in 1994
Authors: Robert D. Cunningham
Journal: JAMA (1995)

<h3>To the Editor.</h3> —According to Drs Goldman and Carra,<sup>1</sup>"The US strategy [to prevent childhood lead poisoning] must begin to focus more than ever on poor, nonwhite, and inner-city children." Perhaps, instead of universal screening, "recent data... indicate the need for a more targeted approach." But, compelled by the Centers for Disease Control and Prevention (CDC) 1991 recommendation for universal blood screening of all young children for lead poisoning, one state after another has passed laws requiring universal childhood blood lead testing. Delaware is the most recent state to pass such a law, requiring all children to have blood lead screening performed at least once, preferably around the age of 1 year. Without lead screening, the child would not be admitted to day care; or if the child has reached 5 years of age without having a blood lead level checked, he or she would not be admitted to
Toll-like receptor 9–induced type I IFN protects mice from experimental colitis
Authors: Kyoko Katakura, Jongdae Lee, Daniel Rachmilewitz, Gloria Li, Lars Eckmann, Eyal Raz
Journal: Journal of Clinical Investigation (2005)

PPARγ agonists but not PPAR antagonists, as listed in Table 2, have shown inhibitory effects on HSCs and antifibrotic effects in animal models with liver fibrosis and patients with NASH.
Massachusetts Department of Public Health
Authors: Allan R. Cunningham
Journal: New England Journal of Medicine (1949)

CONSULTATION CLINICS FOR CRIPPLED CHILDREN IN MASSACHUSETTSThe June schedule for Consultation Clinics for Crippled Children in Massachusetts under the provision of the Social Security Act follows:SCHOOL MEDICINE IN MASSACHUSETTSTo no one are the deficiencies of school medical services more acutely a source of vexation than to the average school physician. Most school physicians, sooner or later, experience a sense of frustration and aimlessness regarding the methods and objectives of their school work, though often at the outset of their incumbency they may have high enthusiasm. School physicians are public-health officers; therefore, it is the responsibility of those . . .
Fulminant delta hepatitis in chronic asymptomatic HBsAg carriers
Authors: N. Tassopoulos
Journal: JAMA (1985)

<h3>To the Editor.—</h3> In a recent issue ofThe Journal, De Cock et al<sup>1</sup>presented two cases of fulminant delta hepatitis in two male homosexual patients with chronic hepatitis B virus (HBV) infection. We followed up prospectively, for at least six months, 546 adults with acute sporadic hepatitis B surface antigen (HBsAg)-positive hepatitis who were hospitalized at the Athens Hospital for Infectious Diseases, Greece, between May 1981 and May 1983. Using a sensitive enzyme immunoassay (Corzyme M) for the determination of the core antigen of HBV (anti-HBc IgM) we found that 43 (7.9%) of the 546 patients were anti-HBc IgM negative. These patients were considered as asymptomatic chronic HBsAg carriers with a superimposed acute non-B hepatitis.<sup>2</sup> Twenty-two (51.2% ) of the 43 cases were diagnosed as having delta antigen superinfection, using sensitive radioimmunoassays for the detection of delta antigen, anti-delta IgG, and anti-delta IgM.<sup>3,4</sup>Homosexual promiscuity and parenteral
A Manual of Modern Gastric Methods, Chemical, Physical and Therapeutical.
Journal: JAMA (1900)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Delaware State Medical Society.
Journal: JAMA (1884)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Medical Education and Professional Competence
Journal: JAMA (1970)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Arch Int Pharmacodyn et Therapie, Ghent
Journal: JAMA (1966)

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Can depression be categorized?
Authors: E. R. Gonzalez
Journal: JAMA (1980)

An extensive and expensive effort is being made to learn more about the depressive disorders in a five-year collaborative project now in progress under National Institute of Mental Health (NIMH) auspices. Participating investigators stress that they are only halfway through the intake procedure (which should yield an eventual total of 1,000 to 1,100 patients), are still compiling current data, and view their interim findings as quite tentative. In fact, several of the investigators on the project were concerned that a report of their current findings, such as this article, might be misconstrued. As the article went to press,<i>JAMA</i>MEDICAL NEWS was apprised of various disagreements among the investigators on such issues as the meaning of findings on control subjects at one institution and the ramifications of the "endogenous concept" of depression. The goals of the project, which will cost at least $5 million and is now in its third