tbuckley/cabot-search huggingface dataset:
Decisions in the treatment of ventricular ectopic activity
Authors: R. J. Myerburg
Journal: JAMA (1978)

EACH use of an antiarrhythmic agent for control of ventricular ectopic activity requires careful consideration of the balance between the indication for use of the drug (based on prognostic implications of ventricular ectopic activity) and undesirable potential side effects that may arise as a result of their use. Side effects include allergic or toxic systemic effects, depression of cardiac mechanical function, paradoxical arrhythmogenesis, and CNS effects; they occur with sufficient frequency, in the context of the limited number of drugs available, to create legitimate concern about appropriate use. The purpose of this communication is to outline settings in which antiarrhythmic agents should or should not be used for various forms of ventricular ectopic activity. The clinical context of ventricular ectopic activity is paramount. <h3>Ischemic Heart Disease</h3> Ventricular ectopic activity in the setting of ischemic heart disease constitutes a risk factor for potentially lethal arrhythmias or sudden death. The effectiveness of
TERPEZONE
Authors: S. Adolphus Knopf
Journal: JAMA (1933)

<h3>To the Editor:</h3> —Terpezone, Inc., is distributing a circular advertising "Terpezone," in which it quotes various favorable statements ascribed to different individuals. Among these is one made by me nearly twenty years ago (1914). It is true that, in 1913, a limited personal experience with Terpezone, reenforced by the enthusiasm of an assistant in whom I placed much confidence, led me to ascribe favorable results in cases that more mature judgment might explain on the basis of autosuggestion. I stopped the use of Terpezone inhalation after a sufficient trial had convinced me of its lack of value. For many years I have not considered it of any importance as a therapeutic agent. [Note.—After examination of the evidence on Terpezone as a remedy in pulmonary tuberculosis, the Council on Pharmacy and Chemistry of the American Medical Association authorized the publication of a lengthy report inThe Journal, April 14, 1928.
Evolving resolve
Authors: Walter Veit, David Spurrett
Journal: Behavioral and Brain Sciences (2021)

Abstract The broad spectrum revolution brought greater dependence on skill and knowledge, and more demanding, often social, choices. We adopt Sterelny's account of how cooperative foraging paid the costs associated with longer dependency, and transformed the problem of skill learning. Scaffolded learning can facilitate cognitive control including suppression, whereas scaffolded exchange and trade, including inter-temporal exchange, can help develop resolve.
Vasectomy
Authors: Stanwood S. Schmidt
Journal: JAMA (1988)

The study by Dr Alderman<sup>1</sup>in this issue concerns the operation most commonly performed on adult men, elective vasectomy for family planning. The author, using the most popular technique of vasectomy (ie, cutting the vas deferens, excising a segment, and ligating the cut ends), reports 97 failures among 5331 men who were available for follow-up. In some of these failures the semen was never clear of sperm; in others sperm reappeared, sometimes several years after initial negative testing. These findings document the fact that the patient can eliminate the sperm from the urethral side of the vas deferens only to have the ducts rejoin later. This should be of deep concern to both the patient and his surgeon. Both need to know when sterility can be considered permanent. An operation with an uncertain result is not a good operation. See also p 3142. Consent to perform surgery is a
GASTRIC SECRETION IN SLEEP
Journal: JAMA (1924)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Techniques Reduce Contamination
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Practical Points in Nursing for Nurses in Private Practice, with an appendix, etc.
Journal: JAMA (1896)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Nonfatal, Unintentional Medication Exposures Among Young Children—United States, 2001-2003
Journal: JAMA (2006)

Young children are vulnerable to inadvertent exposure to prescription and over-the-counter (OTC) medications, especially when these items are not stored securely. In 2002, according to death certificate data, 35 children aged < or =4 years died from unintentional medication poisonings in the United States (CDC, unpublished data, 2005). In 2003, according to reports to U.S. poison control centers, pharmaceuticals accounted for 1,336,209 (55.8%) of unintentional chemical or substance exposures. Of those pharmaceutical exposures, 568,939 (42.6%) involved children aged <6 years. For this report, CDC analyzed 2001-2003 data from hospital emergency department (ED) visits reported by the National Electronic Injury Surveillance System--All Injury Program (NEISS-AIP). The results of this analysis indicated that, during 2001-2003, an estimated 53,517 children aged < or =4 years were treated annually in U.S. EDs for unintentional medication exposures. An estimated 72% of these exposures were in children aged 1-2 years. Children aged < or =4 years can reach items on a table, in a purse, or in a drawer, where medications are often stored; young children also tend to put objects they find in their mouths. Parents and others responsible for supervising children should store medications securely at all times, keep them out of the reach of children, and be vigilant in preventing access by children to daily-use containers such as pill boxes.
Abstract P082: Lower Adiponectin Levels May Underlie Association Between Depressive Symptoms And Markers of Cardiometabolic Health
Authors: Cari J Clark, Qi Wang, Hongfei Guo, Joyce T Bromberger, Peter Mancuso, Howard M Kravitz, Kimberly M Henderson, Susan A Everson-Rose
Journal: Circulation (2012)

Introduction: Depressive symptoms have been linked to CVD risk factors, including metabolic dysregulation. One pathway by which depression may influence CVD risk is via alterations in adiponectin, an abundant adipocytokine with anti-inflammatory effects. This mechanism has not been studied in population-based samples. Hypothesis: The relationship of depressive symptoms with metabolic syndrome (MetSyn) and Framingham Risk Score (FRS) will be partly mediated by adiponectin. Methods: Participants were 581 women (61.3% white; 38.7% black) from the Chicago and Pittsburgh sites of the Study of Women’s Health Across the Nation. Adiponectin was measured from stored serum specimens and assayed in duplicate using a commercially available enzyme linked immunosorbent assay and log transformed for analysis. Depressive symptoms were measured with the 20-item Center for Epidemiological Studies Depression Scale (CES-D); a standard cutoff (&gt;16) was used to determine clinically significant symptoms. MetSyn was defined by ATP-III criteria and considered present if the participant had at least 3 of the following: waist circumference &gt;88cm; triglycerides &gt;150 mg/dl; HDL cholesterol &lt; 50 mg/dl; blood pressure &gt; 130 mmHg systolic and / or 85 mmHg diastolic; impaired fasting glucose (&gt;110 mg/dl) or diabetes. The FRS was defined by the participant’s age, smoking status, blood pressure, cholesterol, and use of anti-hypertensives. Logistic regression models were constructed to examine the cross-sectional relationship between depressive symptoms and MetSyn controlling for age, race and study site. A subsequent model included adiponectin to evaluate whether it attenuated the observed association. Linear regression models were used to conduct the same analysis with FRS as the outcome. Due to missing values, analytic sample sizes were 558 for MetSyn and 568 for FRS. Results: 147 women (25.3%) had elevated CES-D scores and 113 (20.7%) met criteria for MetSyn. Average FRS was 8.7 (sd=4.6) and the mean, untransformed adiponectin value was 9.9 (sd=4.9) μ g/mL. In models adjusted for age, race, and study site, women with high CES-D scores had increased odds of MetSyn (OR=1.64; 95% CI=1.03, 2.60) and a higher FRS (estimate=0.98; se=0.41, p&lt;.02). Separate bivariate analyses showed that adiponectin was inversely related to CES-D scores (p=.03), MetSyn (p&lt;.001) and FRS (p&lt;.001). Subsequently including adiponectin in the regression models attenuated the associations between CES-D and MetSyn (OR=1.45; 95% CI=0.89, 2.36) and FRS (estimate=0.76; se=0.41; p=.06). Conclusions: Adiponectin may partially explain the relation between depressive symptoms and measures of cardiometabolic health. Longitudinal studies are needed to more fully understand the temporality of these associations. Supported by NIH/DHHS grants HL091290, AG012505, AG012546, MH59770, AG17719.
Incorrect Author Name
Authors: Daniel Lai, Ashutosh Jadhav
Journal: JAMA Neurology (2014)

8%), although the authors noted a discrepancy in age difference between groups (64 years in the nonfocal group vs 44 years in the focal group).Animal model studies have shown that earlier treatment with HBOT decreases intracranial pressure and improves cerebral oxygenation levels. 5 In combination with the observations by Heckman et al 4 of a generally encephalopathic state portending a poorer outcome, it is possible that the causative pathophysiology of encephalopathy in the nonfocal group is related to increased intracranial pressure.Therefore, the effective therapeutic window of HBOT treatment may be clinically based (ie, prior to onset of encephalopathy for the affected patient).
Improving skin cancer care with a general practitioner training programme
Journal: British Journal of Dermatology (2021)

Skin cancer is the most common form of cancer in the world and the number of patients diagnosed with skin cancer is growing every year.Luckily, most patients with skin cancer can be treated and cured when diagnosed early.General practitioners play an important part in skin cancer care.Optimal recognition of skin cancer by the general practitioner and referral to a dermatologist when necessary are considered very important to make sure every patient with skin cancer can be treated as soon as possible and in the best way.Previous research showed that general practitioners find it hard to distinguish skin cancer from benign, harmless spots on the skin.This leads to a lot of unnecessary referrals to dermatologists and longer waiting lists before a patient can be seen by a dermatologist.In this study from the Netherlands, 83 out of 194 general practitioners in the Nijmegen area were specifically trained on skin cancer care.Afterwards, referral letters to dermatologists from this trained group of general practitioners were studied and compared with referral letters to dermatologists by general practitioners who did not follow the skin cancer training.We found that general practitioners who followed the skin cancer training were more often able to make the right diagnosis, leading to fewer potentially unnecessary referrals to dermatologists.This helps to minimize waiting lists and to make sure patients with skin cancer can still be treated in the fastest and best way in the future, when more and more people are expected to get skin cancer and the number of dermatologists is limited.
Obesity Declines in US Preschoolers
Journal: JAMA (2013)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Enterovirus Surveillance--United States, 1997-1999
Journal: JAMA (2000)

Enteroviruses accountfor an estimated 10-15 million symptomatic infections in the United States each year (1). At present, 66 serotypes of enteroviruses are recognized, including three poliovirus serotypes (2). A range of diseases is associated with nonpolio enterovirus infections, including aseptic meningitis, encephalitis, neonatal enteroviral disease, myocarditis, pericarditis, chronic infections among persons with compromised immune systems, poliomyelitis-like illness, hand-foot-and-mouth disease, nonspecific upper respiratory disease, and other manifestations (3). This report summarizes data from the National Enterovirus Surveillance System (NESS) and describes temporal trends of reported enterovirus infections in the United States during 1997-1999.
Proceedings of the international symposium on bone marrow therapy and chemical protection in irradiated primates, Aug 15-18, 1962, Rijswijk (Z.H.) The Netherlands.
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Money Improves Whiplash Patients
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Correction: Prevalence of reflex anal dilatation
Authors: P Drs, J Hughes
Journal: BMJ (1989)

Many reports document a variety of neurological complications resulting from both intravenous and intrathecal administration of methotrexate, but acute cerebral oedema is not among them.We describe a patient with acute myeloid leukaemia who developed cerebral oedema after treatment with intrathecal methotrexate.A 23 year old Jamaican woman was admitted with a diagnosis of acute pnyeloid leukaemia (M3).
Editorial: Transplant sensationalism.
Journal: BMJ (1975)

With either treatment oral potassium supplements should be given daily.After intravenous therapy, when the patient is improving, prednisone will need to be given by mouth, the dose being reduced slowly.Because of the delay in the appearance of the maximal effect of parenteral corticosteroids it is prudent for the doctor to give 200 mg ofhydrocortisone intravenously to the patient who is being sent to hospital from an outlying district.Corticotrophin is not usually recommended for the treatment of acute asthma in patients on regular treatment with corticosteroids because the adrenal response in terms ofcortisol output is likely to be inadequate.But patients with severe asthma who were not dependent on steroids have done well when given tetracosactrin depot (1 mg intramuscularly on admission followed by repeated injections of the same dose at 24-hour intervals for three to five days).Though the plasma cortisol levels rose significantly on this regimen they did not reach 100 [Lg/dl.17Again, oral potassium supplements must be given.
Is truth telling to the patient a cultural artifact?
Authors: E. D. Pellegrino
Journal: JAMA (1992)

In this issue of<i>JAMA</i>, Antonella Surbone, MD, describes her dilemma in trying to transfer the ideals of medical ethics she learned in the United States to her native Italy.<sup>1</sup>From her experience in the United States, she found that truth telling and respect for autonomy have become virtual moral absolutes. On the other hand, in Italy, families and physicians often shield patients from painful truths and difficult decisions. As Dr Surbone points out, what is beneficent in one country may seem maleficent in another country. This contrast in moral perspectives, of course, is not unique to the differences between Italy and North America. It has become a worldwide problem as newer models of medical ethics nurtured in the individualistic soil of North America are introduced to other countries with different moral traditions.<sup>2</sup>But similar contrasts may exist within a country, for example, between northern and southern Italy,
Unraveling the Directional Link between Adiposity and Inflammation: A Bidirectional Mendelian Randomization Approach
Authors: Paul Welsh, Eliana Polisecki, Michele Robertson, Sabine Jahn, Brendan M. Buckley, Anton J. M. de Craen, Ian Ford, J. Wouter Jukema, Peter W. Macfarlane, Chris J. Packard, David J. Stott, Rudi G. J. Westendorp, James Shepherd, Aroon D. Hingorani, George Davey Smith, Ernst Schaefer, Naveed Sattar
Journal: Endocrine Reviews (2009)

ContextAssociations between adiposity and circulating inflammation markers are assumed to be causal, although the direction of the relationship has not been proven.