tbuckley/cabot-search huggingface dataset:
Leitfaden der experimentellen Psychopathologie.
Journal: JAMA (1910)

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Books Received
Journal: JAMA (1995)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
LONG-TERM OUTCOME OF PERCUTANEOUS SEPTAL ABLATION FOR SYMPTOMATIC HYPERTROPHIC OBSTRUCTIVE CARDIOMYOPATHY
Authors: Lothar Faber, Dirk Welge, Hubert Seggewiss, Detlef Hering, Olaf Oldenburg, Dieter Horstkotte
Journal: Journal of the American College of Cardiology (2010)
Medical migration and the physician workforce. International medical graduates and American medicine
Authors: F. Mullan
Journal: JAMA (1995)

<h3>Objective.</h3> —Because of the size and growth of the international medical graduate (IMG) contribution to graduate medical education (GME) in the United States, and subsequently to the US physician workforce, it is essential to understand the demographics and patterns of IMG training and practice as well as the routes of entry into the United States. <h3>Data Sources.</h3> —Published data from the American Medical Association, the American Osteopathic Association, and the Association of American Medical Colleges; tabular runs of county-level data contained on the Bureau of Health Professions' Area Resource File. <h3>Results.</h3> —The majority of IMGs who participate in GME in the United States ultimately enter US practices. A significant proportion of exchange visitors eventually enter into permanent practice in the United States, contrary to the intent of the J-1 visa—based GME training as an international educational exchange program. International medical graduates gravitate toward initial residency programs in internal medicine and pediatrics, many of which have unfilled positions; however, IMGs subspecialize at a disproportionately high rate, reducing their net contribution to the generalist pool. Patterns of ultimate practice location of IMGs parallel the patterns of US medical graduates (USMGs). <h3>Conclusions.</h3> —In recent years, participation of IMGs in GME and practice has increased significantly. Most IMGs in GME are not exchange visitors, but are either permanent residents or US citizens. Patterns of specialization and location of IMGs ultimately mirror those of USMGs. National IMG policy must be examined in light of the projected surplus of physicians in the United States. The best option for long-term control of the number of physicians in practice, USMG or IMG, is a system of specifying the number of GME positions nationally. (<i>JAMA</i>. 1995;273:1521-1527)
Correction
Journal: BMJ (1960)

ANY QUESTIONS?DB1UT Unripe green mangoes contain much less vitamin C and carotene, and somewhat less carbohydrate, than are found in the ripe fruit, but they are considerably richer in iron.' 2 No information is readily available about the effects of preservation on the nutritive value of mangoes.From general considerations, however, we might expect that drying would lead to heavy losses of vitamin C and to smaller losses of carotene.Much would depend on the temperature during drying and on the time of storage afterwards.Carotene should suffer only slight losses in mangoes preserved in syrup or oil, and the losses in ascorbic acid ought to be less than after drying.Acid media, such as vinegar, are reputed to favour the preservation of ascorbic acid, but might promote the destruction of carotene.
Hospital Infections
Authors: Jerry D. Smilack
Journal: JAMA (1993)

To the 30 million people hospitalized in the United States every year, the subject of infections acquired while in the hospital is far from theoretical. It can be a matter of life, death, or permanent disability. Nosocomial pneumonia, a total joint prosthesis infection, urinary tract sepsis following prosthetic surgery—all are unwelcome intruders in the halls of medical progress. <i>Hospital Infections</i>illuminates the dark corners of these halls, sweeps out dusty misconceptions, and polishes tools useful to the generalist and specialist alike. Now in its third edition, this book has matured into a position unique in its field. From humble and somewhat unimpressive beginnings over a dozen years ago,<i>Hospital Infections</i>now serves as the definitive resource work in its field. Other texts in infectious diseases expertly cover the spectrum from mundane to hyperesoteric, from the common cold to infections in heart transplant recipients. This text narrows the focus and, in
Treatment of human immunodeficiency virus-related thrombocytopenia with zidovudine
Authors: J. C. Pottage
Journal: JAMA (1988)

Human immunodeficiency virus (HIV)-related thrombocytopenia has been well described and requires therapy in about one half of the patients. Conventional modes of therapy with prednisone, danazol, immunoglobulin, and/or splenectomy have not been uniformly successful. We have administered zidovudine to three patients with HIV-related thrombocytopenia. All three patients responded with a sustained increase in their platelet counts, despite discontinuation of conventional therapy. Interruption of zidovudine therapy was associated with a decrease in platelet count. Concomitant with the elevation in platelet count with zidovudine therapy, there was a reduction in the circulating p24 antigen levels. Whether the elevations in the platelet count in these patients with HIV-related thrombocytopenia is due to the antiviral effect of zidovudine is unknown. It is clear that further studies examining the prospective use of zidovudine in the treatment of HIV-related thrombocytopenia are indicated.
Hypoglycemia Due to Extrapancreatic Mesothelioma
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Periocular Rash
Authors: Huan J Chang
Journal: JAMA (2011)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A polymorphism of the X-linked gene IDS increases the number of females informative for transcriptional clonality assays
Authors: Xylina T. Gregg, Robert Kralovics, Josef T. Prchal
Journal: American Journal of Hematology (2000)

Studies of clonality have been essentialfor understanding the hierarchy of hematopoiesis and the biology of malignancies.Most clonality assays are based on the X chromosome inactivation phenomenon in females; these assays detect protein polymorphisms, differences in DNA methylation, or transcripts of the active X chromosome.Assays based on protein polymorphisms or DNA methylation have significant shortcomings.The major disadvantage of transcriptional assays is their limited applicability since only approximately half of females are informative for these studies.We have developed a new transcriptional assay based on an exonic polymorphism of the X-chromosome gene IDS.This gene is located in the same X-chromosome region (Xq28) as G6PD and p55, two genes with exonic polymorphisms for which we previously developed transcriptional assays.We developed non-radioactive PCR-based assays for rapid screening of genotype and determination of clonality.We also report reaction conditions for a quantitative ligase detection assay of IDS allelic transcripts.The frequency of the IDS polymorphism is 46% in Caucasian females and 39% in African-American females; in combination with G6PD and p55, 76% of Caucasian females and 62% of African-American females are informative for these assays.While this gene is highly polymorphic in Caucasian and African-American females, it is not informative in Oriental females.We established that the IDS gene is in linkage equilibrium with G6PD and p55.Unlike methylation-based assays, this assay is suitable for studying clonality in non-nucleated cells such as platelets and reticulocytes.With the discovery of exonic polymorphisms of other X-chromosome genes, all females should eventually be suitable for X-chromosome transcriptional clonality analysis.Am.
AUTHORS' REPLY
Authors: F. Carey, D Lamb
Journal: Thorax (1993)

Estimating age, sex and period specific constant tar cigarette consumption in the UK In a paper published three years ago (September 1990;45:657-65) we examined trends in smoking associated respiratory diseases up to 1985 in relation to trends in cigarette smoking.In that paper we present- ed graphs for each sex of cumulative con- stant tar cigarette consumption (CCTCC) by age and year of death, and by age and year of birth.We were approached by the Lung and Asthma Information Agency for permission to use these graphs with the request that they be updated to 1990.While
Toxicity of Parathyroid Hormone in Uremia
Authors: S Klahr
Journal: Annual Review of Medicine (1986)

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of coronavirus disease 2019 (COVID-19), emerged in China in December 2019 and quickly spread around the globe, killing more than 4 million people and causing a severe economic crisis. ...Read More
pH and titratable acidity of amino acid mixtures used in hyperalimentation
Authors: J. C. Chan
Journal: JAMA (1972)

The pH and titratable acidity of three amino acid mixtures used in hyperalimentation were determined and compared with those of eight common intravenous solutions. Although the mean pH of the two groups was similar, the mean titratable acidity of the three amino acid mixtures (30.54 mEq/liter) was markedly higher than that of the eight intravenous solutions (0.13 mEq/liter). The high titratable acidity of the amino acid mixtures could be a major factor in the development of metabolic acidosis in hyperalimented infants. The titratable acidity of the eight intravenous solutions did not differ significantly from that of water blanks (0.16 mEq/liter).
THE NEED OF A UNITED MEDICAL PROFESSION.
Journal: JAMA (1893)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
All Psychiatric Experience in a Community
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Autofluorography of the Thyroid Gland by Means of Image Amplification
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
State Boards of Registration.
Journal: JAMA (1904)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The neglected disease: an update
Authors: T. C. Doege
Journal: JAMA (1986)

Seventeen years ago the National Academy of Sciences focused attention on "accidental death and disability,"<sup>1</sup>a "neglected disease" that received little attention from society except, perhaps, for an occasional catastrophe or spectacular incident. Has there been any progress with the problem? Is there a better understanding of why and how disabling injuries occur? Death rates in the United States involving all major categories of unintentional injuries have fallen steadily since World War II. Fatal crashes on highways constitute the most important component. In terms of deaths per 10,000 registered vehicles, there has been a steady decline since the mid-1930s.<sup>2,3</sup>In 1982 there were 46,300 deaths in vehicle-related crashes, the lowest number since 1963; in 1982 the US population was 24% greater than in 1963. Thus, it is apparent there has been progress. A landmark report of the US Surgeon General,<i> Healthy Peopl</i>e, in 1979 called for progress
Phase I study of CNTO 95, a fully human monoclonal antibody (mAb) to αv integrins, in patients with solid tumors
Authors: G. C. Jayson, S. Mullamitha, C. Ton, J. Valle, M. Saunders, M. C. Munteanu, H. Jang, M. Trikha, H. M. Davis, R. A. Beckman
Journal: Journal of Clinical Oncology (2004)

3119 Background: Integrins of the αv family are implicated in tumor angiogenesis and growth. CNTO 95 is a fully human mAb that binds to cellular αv integrins with a KD of ∼5 nM. In a rat aortic ring angiogenesis assay CNTO 95 (∼70 nM) completely inhibited microvessel growth. In human melanoma xenograft models in nude mice and rats CNTO 95 inhibited tumor growth by ∼80% and >99%, respectively (P< 0.0005). Methods: A Phase I dose-escalating study of CNTO 95 in patients with advanced solid tumors refractory to standard therapy is ongoing. CNTO 95 was infused on days 0, 28, 35 and 42, and standard clinical assessments as well as DCE-MRI and FDG-PET were also performed. Results: Thirteen patients, with a median number of two prior systemic therapies (range 1–5), have been enrolled at 0.1, 0.3 and 1.0 mg/kg, n=7, 3 and 3, respectively. Tumor types included ovarian (6), colorectal (4), ureteric (1), PNET (1), and pseudomyxoma peritonei (1). An ileo-femoral DVT was seen in the first cohort, although this was confounded by tumor blockage of the blood supply to that patient's extremity. This cohort was expanded to 6 evaluable patients without additional DLTs. There were no other CNTO 95-related SAEs or Grade 3/4 adverse events. Three ovarian cancer patients (2 at 0.3 mg/kg, and 1 at 1 mg/kg) had stable disease (per RECIST criteria) at day 42 and remain on extended dosing. Dose escalation to a planned study maximum of 10 mg/kg continues. Single dose PK analysis showed that Cmax and AUC appeared to increase in a greater than dose proportional manner on days 1 and 42, perhaps due to a tissue or tumor binding mechanism. No accumulation was observed upon repeat dosing. Conclusions: CNTO 95 is a fully human mAb to αv integrins with anti-tumor and anti-angiogenic properties in rodents. In an ongoing Phase I trial CNTO 95 appears to be well tolerated and 3 patients are on extended therapy. Author Disclosure Employment or Leadership Consultant or Advisory Stock Ownership Honoraria Research Funding Expert Testimony Other Remuneration Centocor Centocor; Johnson & Johnson Centocor; Johnson & Johnson Centocor Centocor Centocor Centocor
Steroids, San Francisco
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal