Enough Is Enough
Authors: Irvine Mason
Journal: Annals of Internal Medicine (2014)

Letters3 June 2014Enough Is EnoughIrvine Mason, MDIrvine Mason, MDFrom Neurology and Pain Management of the Palm Beaches, Jupiter, Florida.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/L14-5011-2 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITORGuallar and colleagues (1) purport that their opinions are facts. They state that most supplements “do not prevent chronic disease or death ... and they should be avoided.”The authors totally disregard the best and most comprehensive study to date, PHS II (2). This study followed nearly 15 000 male physicians aged 50 years or older for up to 13 years. It revealed that use of a Centrum Silver (Pfizer, New York, New York) multivitamin alone reduced the risk for cancer in men from any source by 8%. The study also found that multivitamin use decreased site-specific cancer ...References1. Guallar E, Stranges S, Mulrow C, Appel LJ, Miller ER. Enough is enough: Stop wasting money on vitamin and mineral supplements [Editorial]. Ann Intern Med. 2013;159:850-1. [PMID: 24490268] LinkGoogle Scholar2. Gaziano JM, Sesso HD, Christen WG, Bubes V, Smith JP, MacFadyen J, et al. Multivitamins in the prevention of cancer in men: the Physicians' Health Study II randomized controlled trial. JAMA. 2012;308:1871-80. [PMID: 23162860] CrossrefMedlineGoogle Scholar3. Daily multivitamin usage cut cancer risk by 8% in men. SciTech Daily. 2 November 2012. Accessed at http://scitechdaily.com/daily-multivitamin-usage-cut-cancer-risk-by-8-in-men on 28 April 2014. Google Scholar4. Douaud G, Refsum H, de Jager CA, Jacoby R, Nichols TE, Smith SM, et al. Preventing Alzheimer's disease-related gray matter atrophy by B-vitamin treatment. Proc Natl Acad Sci U S A. 2013;110:9523-8. [PMID: 23690582] CrossrefMedlineGoogle Scholar5. Vitamin B for Alzheimer's and dementia delay and protection, new research study. Examiner.com. 20 May 2013. Accessed at www.examiner.com/article/vitamin-b-for-alzheimer-s-and-dementia-delay-and-protection-new-research-study on 28 April 2014. Google Scholar Author, Article, and Disclosure InformationAuthors: Irvine Mason, MDAffiliations: From Neurology and Pain Management of the Palm Beaches, Jupiter, Florida.Disclosures: Authors have disclosed no conflicts of interest. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L14-0080. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoEnough Is Enough: Stop Wasting Money on Vitamin and Mineral Supplements Eliseo Guallar , Saverio Stranges , Cynthia Mulrow , Lawrence J. Appel , and Edgar R. Miller III Enough Is Enough Balz Frei , Bruce N. Ames , Jeffrey B. Blumberg , and Walter C. Willett Enough Is Enough Deborah Stepp Enough Is Enough Thomas R. Friberg Enough Is Enough Jessica Fargnoli , Joyce Greenleaf , and Melissa Hafner Enough Is Enough Eliseo Guallar , Saverio Stranges , Cynthia Mulrow , Lawrence J. Appel , and Edgar R. Miller III Enough Is Enough Jessica Fargnoli , Joyce Greenleaf , and Melissa Hafner Enough Is Enough Thomas R. Friberg Enough Is Enough Deborah Stepp Enough Is Enough Eliseo Guallar , Saverio Stranges , Cynthia Mulrow , Lawrence J. Appel , and Edgar R. Miller III Enough Is Enough Balz Frei , Bruce N. Ames , Jeffrey B. Blumberg , and Walter C. Willett Metrics 3 June 2014Volume 160, Issue 11Page: 808KeywordsBrainCancer preventionGastrointestinal cancersInfantsMacular degenerationNeural tube defectsProstate cancerVitamin CVitamins ePublished: 3 June 2014 Issue Published: 3 June 2014 Copyright & PermissionsCopyright © 2014 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...