Body Mass Index and Risk for End-Stage Renal Disease
Authors: Kamyar Kalantar-Zadeh, Joel D. Kopple
Journal: Annals of Internal Medicine (2006)

Letters2 May 2006Body Mass Index and Risk for End-Stage Renal DiseaseKamyar Kalantar-Zadeh, MD, PhD, MPH and Joel D. Kopple, MDKamyar Kalantar-Zadeh, MD, PhD, MPHFrom Harbor-UCLA Medical Center, Torrance, CA 90502.Search for more papers by this author and Joel D. Kopple, MDFrom Harbor-UCLA Medical Center, Torrance, CA 90502.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-144-9-200605020-00021 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:The strong association between obesity and the risk for end-stage renal disease (ESRD) that Hsu and colleagues (1) reported is a valuable addition to the list of risk factors for ESRD. It seems possible, however, that these findings are influenced by survival bias (2), especially if obese individuals with CKD have a paradoxically better survival chance than nonobese individuals. An inverse association between obesity (including morbid obesity) and survival has been frequently shown among patients with advanced CKD who undergo maintenance hemodialysis (3). Therefore, it is possible that even obese patients with earlier-stage CKD (that is, those ...References1. Hsu CY, McCulloch CE, Iribarren C, Darbinian J, Go AS. Body mass index and risk for end-stage renal disease. Ann Intern Med. 2006;144:21-8. [PMID: 16389251] LinkGoogle Scholar2. Rothman K, Greenland S. Sources of bias.. In: Rothman K, Greenland S, eds. Modern Epidemiology. Philadelphia: Lippincott-Raven; 1998. Google Scholar3. Kalantar-Zadeh K, Kopple JD, Kilpatrick RD, McAllister CJ, Shinaberger CS, Gjertson DW, et al. Association of morbid obesity and weight change over time with cardiovascular survival in hemodialysis population. Am J Kidney Dis. 2005;46:489-500. [PMID: 16129211] CrossrefMedlineGoogle Scholar4. Keith DS, Nichols GA, Gullion CM, Brown JB, Smith DH. Longitudinal follow-up and outcomes among a population with chronic kidney disease in a large managed care organization. Arch Intern Med. 2004;164:659-63. [PMID: 15037495] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Harbor-UCLA Medical Center, Torrance, CA 90502.Disclosures: None disclosed. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoBody Mass Index and Risk for End-Stage Renal Disease Chi-yuan Hsu , Charles E. McCulloch , Carlos Iribarren , Jeanne Darbinian , and Alan S. Go Body Mass Index and Risk for End-Stage Renal Disease Chi-yuan Hsu , Carlos Iribarren , and Alan S. Go Body Mass Index and Risk for End-Stage Renal Disease Micah L. Thorp Metrics Cited byKidney TransplantationEffect of the Obesity Epidemic on Kidney Transplantation: Obesity Is Independent of Diabetes as a Risk Factor for Adverse Renal Transplant OutcomesAssociation Between Body Mass Index and Mildly Decreased Estimated Glomerular Filtration Rate in Chinese Adults With Early Chronic Kidney DiseaseThe association of chronic kidney disease and waist circumference and waist-to-height ratio in Chinese urban adultsInflammation and nutrition in children with chronic kidney diseaseEffect of Taekwondo Training on Abdominal Fat, Kidney Function and Inflammatory Factors in Abdominal Obese elderly WomenObésité et hémodialyse : le paradoxeRacial and survival paradoxes in chronic kidney diseaseBody Mass Index and Mortality in CKD 2 May 2006Volume 144, Issue 9Page: 701KeywordsBody mass indexConflicts of interestMedical dialysisMedical risk factorsMorbid obesityObesityOverweightRenal failureRisk management ePublished: 2 May 2006 Issue Published: 2 May 2006 Copyright & PermissionsCopyright © 2006 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...