tbuckley/cabot-search huggingface dataset:
Therapeutics.
Journal: JAMA (1902)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A retrospective analysis of the association between perioperative carcinoembryonic antigen level and prognosis in stage III colorectal cancer
Authors: R. Kozuki, E. Shinozaki, H. Osumi, T. Wakatsuki, M. Suenaga, T. Ichimura, M. Ogura, T. Suzuki, Y. Ota, I. Nakayama, D. Takahari, K. Chin, T. Nagasaki, T. Akiyoshi, T. Konishi, Y. Fujimoto, S. Nagayama, Y. Fukunaga, M. Ueno, K. Yamaguchi
Journal: Annals of Oncology (2018)
Ethnic differences in the use of peritoneal dialysis as initial treatment for end-stage renal disease
Authors: C. Barker-Cummings
Journal: JAMA (1995)

<h3>Objective.</h3> —To evaluate the influence of ethnicity on the use of peritoneal dialysis (PD) as initial treatment for end-stage renal disease (ESRD) after controlling for other patient characteristics. <h3>Design.</h3> —Inception cohort analysis of incident ESRD patients. <h3>Patients.</h3> —All African-American and white patients (N=10 726) who began treatment for ESRD at dialysis centers in North Carolina, South Carolina, and Georgia and reported to ESRD Network 6 between January 1,1989, and December 31, 1991. <h3>Main Outcome Measure.</h3> —Odds ratios (ORs) of the association between ethnicity and PD as initial treatment modality. <h3>Results.</h3> —African-American patients were 56% less likely than whites to use PD (OR, 0.44; 95% confidence interval [CI], 0.40 to 0.49). This difference persisted (OR, 0.45; 95% CI, 0.38 to 0.52) after multivariable adjustment for age, education, social support, home ownership, functional status, albumin level, hypertension, history of myocardial infarction, peripheral neuropathy, and comorbid diabetes. <h3>Conclusions.</h3> —Ethnic differences in initial PD use cannot be explained by many demographic, socioeconomic, and comorbid factors associated with the use of PD as initial treatment for ESRD. (<i>JAMA</i>. 1995;274:1858-1862)
AUTHOR'S REPLY
Authors: D. J Lane
Journal: Thorax (1992)

Alternative and complementary medicine for asthma Readers of the review by D J Lane and T V Lane (November 1991;46:787-97) might conclude that hypnosis has little to offer asthmatic patients.Although the report of Ewer and Stewart' is quoted as showing improvement in symptom scores and some peak expiratory flow rates and decreased use of bronchodilators, no mention is made of a 74-9% improvement (p < 0-01) in the degree of bronchial hyperresponsiveness to a stan- dardised methacholine challenge test.These authors state that "while our hypnotic tech- nique does not eliminate bronchial hyperresponsiveness it does provide a clinically useful and non-toxic adjuvant to drug treat- ment that might benefit about half of the asthmatic population."This approach could well reduce the use of the toxic drugs, such as troleandomycin, gold, azathioprine, and methotrexate, mentioned as steroid sparing agents by Shiner and Geddes.2The British Tuberculosis Association's study3 did not report negative results as stated in the review.On the contrary, "independent clinical assessors considered the asthma to be much better in 59% of the hypnosis groups and in 43% of the control group, the difference being significant."These results were obtained by using only direct suggestion under hypnosis plus autohypnosis daily; more advanced methods, such as reciprocal inhibition, were not used.In my own study4 it was possible to with- draw oral prednisolone or to reduce the dose in 14 of the 16 patients treated by hypnosis.The number of hospital admissions during the first year of hypnotherapy fell to 13, compared with 44 during the previous year.This represented a reduction of 249 hospital days, which, at 1988 costs (£170 per day), saved the NHS £42 330.As some 55 000 adults are admitted each year for asthma, savings to the NHS could be considerable if hypnotherapy were to be used more widely.
Leprosy Today
Authors: Charles C. Shepard
Journal: New England Journal of Medicine (1982)

Leprosy is a chronic infectious disease chiefly involving the skin and peripheral nerves (and nasal mucosa in lepromatous disease), and Mycobacterium leprae is the etiologic agent. The association of chronic skin disease with anesthesia or hypesthesia should always suggest leprosy. The form of the disease varies along a spectrum from the lepromatous to the tuberculoid. The lepromatous form is extensive and diffuse, with many bacilli present. The tuberculoid form is often limited to a single skin lesion, but nerve involvement may be severe. The chief (or sole) source of new infections is the untreated or ineffectively treated patient with multibacillary . . .
Impotence
Authors: Q. H. Siraj
Journal: Clinical Nuclear Medicine (1998)

Impotence, an inability to achieve or maintain an erection suitable for sexual intercourse, is a common male ailment with a reported incidence of 25% at 65 years of age [1]. Erectile dysfunction may be caused by psychogenic, endocrine, neurological, pharmacological or vascular factors. Contrary to the long-held belief, it has now been established that only a small proportion (about one-quarter) of the subjects have purely functional impotence; further, the majority (over 85%) of patients with organic impotence have a vasculogenic aetiology [2].KeywordsErectile DysfunctionVenous OutflowTunica AlbugineaArterial InflowPenile ArteryThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
New Instrument.
Journal: JAMA (1904)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Étude sur les narcolepsies: Considérations sur l'appareil régulateur du sommeil.
Journal: JAMA (1931)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Thrombopoietin level is inversely related to blast count, not platelet number, in Down syndrome neonates with transient myeloproliferative disorder
Authors: Motoki Bonno, Eiichi Azuma, Hajime Kawasaki, Xao‐Li Zhang, Yoshihiro Komada, Masahiro Hirayama, Masamune Higashigawa, Masakazu Umemoto, Tadashi Koike, Takashi Kato, Tomoyuki Tahara, Hiroshi Miyazaki, Minoru Sakurai
Journal: American Journal of Hematology (1998)

Transient myeloproliferative disorder (TMD) in neonates with Down syndrome is characterized by increased megakaryoblastic cells in the peripheral blood. Despite their spontaneous regression in weeks, prognosis is not always favorable because of fatal hepatic fibrosis. In this study, blood thrombopoietin (TPO) levels were measured by ELISA in six TMD patients and the expression of c-Mpl, a ligand for TPO, was examined on the blast cells from four patients by flow cytometer. At the onset, TPO level was undetectable in one patient and significantly lower in five patients than six neonatal controls (mean 0.52 fmol/ml, range 0.30–0.93 vs. 3.70, 1.38–8.33, P < 0.001), although platelet counts were similar (mean 321 × 109/l, range 42–1,040 vs. 253 × 109/l, 124–381). Two patients died of hepatic failure. TPO levels were measured in five patients after regression of the blast cells. With regression of blast cells, TPO levels were remarkably increased in four survived patients. In one patient with hepatic failure, TPO level was poorly elevated and relatively lower compared to the others. TPO levels were inversely correlated with blast numbers (r = −0.85, P < 0.001), but not with platelet counts (r = 0.426). Blast cells from four patients were all positive for c-Mpl. Our findings suggest that megakaryocyte mass is a major regulator of TPO levels and hepatic failure may affect the TPO level because liver is a major source of TPO production. Am. J. Hematol. 58:267–272, 1998. © 1998 Wiley-Liss, Inc.
ORGANIZATION SECTION
Journal: JAMA (1949)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Sodium channel blockers and uridine triphosphate: effects on nasal potential difference in cystic fibrosis mice
Authors: S. Ghosal, C.J. Taylor, W.H Colledge, R Ratcliff, M.J Evans
Journal: European Respiratory Journal (2000)

Sodium channel inhibitors block the enhanced Na+ reabsorption in cystic fibrosis (CF). Extracellular nucleotides facilitate Cl- secretion via Ca2+ gated Cl- channels. A combination of these effects may produce less viscid secretions in CF which are easier to expectorate. This study examined the effects of combining sodium channel blockers with uridine triphosphate (UTP) on nasal membrane potential difference (PD) in CF insertional null mutant mice (cftr(tm1HGU)), deltaF508 homozygous mice (cftr(tm1Cam)) and matched control animals. Median basal PD in the insertional CF mice and deltaF508 CF mice were -28 and -34 mV respectively. These values were significantly different to the control animals (-20 mV). Amiloride and loperamide reduced the PD in cftr(tm1HGU) CF mice (deltaPD 13 mV &amp; 15 mV respectively) suggesting Na+ blockade. The subsequent addition of UTP in a chloride-free vehicle increased the PD (deltaPD -8- -12.5 mV). DeltaF508 mice showed significantly greater responses compared with CF insertional null mutant mice (p&lt;0.05). The action of UTP was brief and not prolonged by the addition alpha-beta-methylene-adenosine 59 diphosphate. Suramin, a competitive antagonist of P2 purinoceptors blocked the action of UTP. In conclusion, this study demonstrated dose dependant nasal membrane potential changes in differences mice with uridine triphosphate in the presence of sodium channel blockers suggestive of chloride secretion. More stable analogues of uridine triphosphate in combination with long acting sodium channel blockers such as loperamide may have therapeutic potential in cystic fibrosis.
General Ophthalmology: A Short Treatise for Students and Practitioners
Journal: JAMA (1935)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
ADDRESSES.
Journal: JAMA (1890)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A Prognostic Model of Therapy-Related Myelodysplastic Syndrome for Predicting Survival and Transformation to Acute Myeloid Leukemia
Authors: Alfonso QuintÀs-Cardama, Hawk Kim, Jianqin Shan, Elias Jabbour, Stefan Faderl, William G. Wierda, Farhad Ravandi, Tapan Kadia, Sa A. Wang, Sherry Pierce, Hagop M Kantarjian, Guillermo Garcia-Manero
Journal: Blood (2011)
Addendum to UEGW Abstract book (Gut 1996; 39 (suppl 3))
Authors: A Echarri, F Borda, J Martinez-Peniuela, F Jimenez, C Valenti', I Elizalde
Journal: Gut (1996)

Mast cells are responsable of an increased release of histamine and inflam- matory mediators which may play a role in the development of duodenal ulcers in HP infected patients.Aims: The aim of the present study is to evaluate the presence and intensity of intraepithelial mast cells in antral mucosa of control cases and patients infected by HP, assesing its influence in ulcer development, gastritis inflammatory activity and response to erradicating treatment.Material and Methods: Antral biopsies of 23 cases without histological findings HP (-), 27 HP (+) gastritis without ulcer and 30 duodenal ulcer HP (+) cases were studied.Semiquantitative scoring (1 to 4) was used to measure intraepithelial mast cells intensity.Sidney classification was employed to asses gastritis intensity.In cases of ulcer, biopsies were taken at diagnosis and 1 month after erradicating treatment with Omeprazole and antibiotics.Spearman, Fisher, Mann Whitney and Wilcoxon stadistical tests were performed.Results: lntraepithelial mast cells were present in 27/30 ulcers (90%), 3/27 gastritis (11%) and absent in controls (p < 0.001).Presence intensity was higher in ulcers: 2.43 0.82 than in gastritis: 1.11 ± 0.32 (p < 0.00001).No differences were found between gastritis and control groups.Mast cells density was not related to gastritis intensity (r = 0.14, p = n.s.).After successful erradicating treatment (26/30), mast cells presence dropped to 15.4% (p < 0.001) and infiltration intensity to 1.15 + 0.37 (p < 0.00001).'p < 0.01 compared with normal controls UDCA treatment did not alter HSP antibody levels in any stage of PBC (Pre UDCA: 1.304 + 0.055; Post UDCA: 1.301 + 0.056).Conclusion: Antibodies to HSP are elevated in PBC, especially in early stage disease; that short term UDCA therapy does not affect this response and that the presence of antibodies to HSP may suggest a role for this protein in the pathogenesis of PBC.The trend towards higher levels in early stage disease may suggest a role in the initiation of this disease, which once established may be self perpetuating.Further studies with longer treatment with UDCA are needed.
THE USE OF HYPODERMIC INJECTIONS OF CAFFEINE IN THE TREATMENT OF POST-PARTUM HAEMORRHAGE
Journal: JAMA (1990)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
First Official List of Books, Pamphlets, Posters, Charts and Periodicals on Food and Nutrition
Journal: JAMA (1942)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Censorship of medical journals in occupied Japan
Authors: S. Nishimura
Journal: JAMA (1995)

Before the Pacific War, Yukie Kiriyama attended the University of Washington in Seattle as a foreign student. At a gathering of Japanese nationals, she saw a film that asserted, "Japan is a divine country, and will eventually incorporate Southeast Asia into the Empire." Thereafter, Kiriyama was uncomfortable with Japanese militarism; when the war ended, she felt revived at 31 years of age. In autumn 1945, Kiriyama began working as a reader and translator for the Magazine Section of the Press, Pictorial, and Broadcast Division (PPB) of the Civil Censorship Detachment (CCD) of the Occupation forces (officially known as the Supreme Commander for the Allied Powers [SCAP]). Kiriyama's colleagues included Senzô Furuya, a 51-year-old former professor of English literature at Nippon University, who began working at the CCD after the university was completely demolished by US air raids, and Noboru Sakai, 28 years old, a graduate of the English Department of