tbuckley/cabot-search huggingface dataset:
CORRECTION
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
AKCHIVES OF DERMATOLOGY AND SYPHILOLOGY
Journal: British Journal of Dermatology (1937)

British Journal of DermatologyVolume 49, Issue 2 p. 83-83 AKCHIVES OF DERMATOLOGY AND SYPHILOLOGY First published: February 1937 https://doi.org/10.1111/j.1365-2133.1937.tb11158.xAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat No abstract is available for this article. Volume49, Issue2February 1937Pages 83-83 RelatedInformation
Lung Cancer, Proximity to Industry, and Poverty in Northeast England
Authors: Tanja Pless-Mulloli, Peter Phillimore, Suzanne Moffatt, Raj Bhopal, Chris Foy, Chris Dunn, Jacqui Tate
Journal: Environmental Health Perspectives (1998)

This study assesses whether deprived populations living close to industry experience greater mortality from lung cancer than populations with comparable socioeconomic characteristics living farther away. Mortality data, census data, a postal survey of living circumstances, historic and contemporary data on air quality and a historic land-use survey were used. Analysis was based on two conurbations in England, Teesside and Sunderland. Housing estates in Teesside were selected based on socioeconomic criteria and distinguished by proximity to steel and chemical industries; they were grouped into three zones: near (A), intermediate (B), and farther (C), with a single zone in Sunderland. We included 14,962 deaths in 27 estates. Standardized mortality ratios (SMR) for lung cancer [International Classification of Diseases #9 (ICD-9) 162] and cancers other than lung (ICD-9 140-239, excluding 162), and sex ratios were calculated. Mortality from lung cancer was well above national levels in all zones. For men, a weak gradient corresponding with proximity to industry at younger ages reversed at older ages. In women 0-64 years of age, stronger gradients in lung cancer mortality corresponded with proximity to industry across zones A, B, and C (SMR = 393, 251, 242, respectively). Overall rates in Teesside were higher than Sunderland rates for women aged 0-64 years (SMR = 287 vs. 185) and 65-74 years (SMR = 190 vs. 157). The association between raised lung cancer mortality and proximity to industry in women under 75 years of age could not be explained by smoking, occupation, socioeconomic factors, or artifact. Explanations for differences between men and women may include gender-specific occupational experiences and smoking patterns. Our judgment is that the observed gradient in women points to a role for industrial air pollution.
Corrigendum: Design, evaluation and structure-activity relationship studies of the AChE reactivators against organophosphorus pesticides
Authors: Kamil Musilek, Martin Dolezal, Frank Gunn-Moore, Kamil Kuca
Journal: Medicinal Research Reviews (2011)

The following acknowledgment was mistakenly omitted in the print and PDF version of this article in issue 31(4): “The work was supported by Grant Agency of Ministry of Education, Youth and Sports (Czech Republic) - grant no. ME09086.” Furthermore, corresponding author Musilek has as an additional affiliation: University Hospital Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove. We regret any inconvenience this may have caused.
CLOSURE OF FISTULOUS OPENINGS THROUGH ALVEOLAR PROCESS INTO ANTRUM OF HIGH-MORE
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Expert panel convened by FDA recommends Haemophilus influenzae type B vaccine should continue in use for children older than 2 years
Authors: C. Marwick
Journal: JAMA (1987)

DESPITE RESULTS FROM one study that questions efficacy, use of the vaccine for immunizing children older than 2 years against<i>Haemophilus influenzae</i>type b (Hib) should continue. That recommendation comes from a group of experts called together by the Food and Drug Administration (FDA). While the FDA has not made a formal decision on the matter, it has indicated that immunizations should indeed continue. A case-control study in Minnesota had questioned the efficacy and perhaps even the safety of the current vaccine. In 45 children aged 18 to 24 months with confirmed<i>H influenzae</i>infection, 17 cases occurred among vaccinated children. So far, this is the only study to show lack of efficacy of this vaccine. But the report resulted in the FDA's conducting a workshop for experts in polysaccharide bacterial diseases and epidemiology to review data from ongoing studies of this vaccine. A seven-member panel chaired by David Karzon,
Lasker awards honored long-term achievers
Authors: Charles Marwick
Journal: JAMA (1984)

Less than two months ago, the Albert Lasker Medical Research Awards were presented for the 38th time in New York City. Herewith, an account of the work, part of it done some time ago, for which these three $15,000 prizes were awarded: In less than three decades, from the mid-1950s to the present day, pediatric practice has undergone a revolution. The<b>Public Service Award</b>recognized two leaders of the revolution,<b>Saul Krugman</b>, MD, and<b>Maurice R. Hilleman</b>, PhD. When Krugman became an instructor in pediatrics at New York University School of Medicine in 1948, measles, diphtheria, pertussis, and poliomyelitis were major viral diseases of childhood, causing permanent aftereffects in all too many cases. But it was only a year later, in 1949, that John Enders, PhD, showed it was possible to cultivate polio virus, and the golden age of clinical virology essentially began. With the ability to manipulate viruses in
The effect of maximum tumor diameter on disease control in intermediate and high-risk prostate cancer patients treated with brachytherapy boost.
Authors: Matthew Parsons, Ryan Hutten, Ashley Khouri, Alexander Tward, Glen Morrell, John Stuart Peterson, Donald Maurice Cannon, Shane Lloyd, Skyler B Johnson
Journal: Journal of Clinical Oncology (2021)

252 Background: Larger maximum tumor diameter (MTD) has been associated with worse prostate cancer outcomes for those undergoing surgery as well as salvage radiation. MTD is also an important consideration for patients weighing active surveillance. However, the impact of MTD in intermediate and high-risk prostate cancer treated with external beam radiotherapy (EBRT) and brachytherapy boost is unknown. We set out to evaluate MTD of the dominant nodule on MRI as a prognostic factor in patients treated with EBRT and brachytherapy boost for localized prostate cancer. Methods: Patients with prostate cancer treated with EBRT and brachytherapy boost were identified from an institutional database. In patients with a pretreatment MRI, data on MTD were retrospectively collected. Clinical data including age, ADT use, pretreatment PSA, International Society of Urologic Pathology (ISUP) group, clinical T-stage, and presence of adverse pathology on imaging (either seminal vesicle invasion or extraprostatic extension) were also collected. Multivariable and univariable cox proportional hazards models for biochemical failure (BF) and distant metastasis (DM) were produced in patients with MTD grouped by receiver operating characteristic (ROC) cutpoint. Cumulative hazard functions for BF and DM were compared with log-rank test and stratified by ISUP group. Results: Of 191 patients treated with EBRT and brachytherapy boost, 113 had pretreatment MRI and available MTD measurement. Median follow up was 40 months (interquartile range 23-66 months) and median MTD was 17 mm (interquartile range 13-22mm). Increasing MTD was associated with higher T stage and increased ADT use. ROC cutpoint optimization identified MTD of 24mm to be the optimal cut-point for both BF and DM. On univariate log-rank analysis, patients with MTD &gt; 24mm had higher 5-year BF (31% vs 4%, p = 0.004) and DM (21% vs 4%, p = 0.002) than those with MTD≤24. Stepwise multivariable cox model for BF (P = 0.130, HR 1.08, 95% CI 0.98-1.21) and DM (P = 0.115, HR 1.09, 95% CI 0.98-1.23), MTD did not demonstrate statistical significance when controlling for clinical t-stage, adverse pathologic features on imaging, ISUP group, and ADT use. However, in patients with ISUP group 4-5 disease, MTD &gt; 24 was independently associated with increased risk of DM (P = 0.032, HR 1.18, 95% CI 1.01-1.37). Conclusions: This is the first study to evaluate MTD on MRI as a prognostic factor in the setting of brachytherapy boost. These results demonstrate that for patients treated with EBRT and brachytherapy boost, MTD is independently associated with risk for metastasis in patients with ISUP grade 4 and 5 disease. Although these results require further validation, this suggests a possible role for MTD as a factor in risk assessment models and clinical decision-making.
In Reply
Authors: William E. Winter, G. Larry Maxwell, Chunqiao Tian
Journal: Journal of Clinical Oncology (2008)

efficacy of cytoreductive surgery plus platinum/taxane-based chemotherapy for stage IV EOC patients.By doing so, Winter et al 1 might identify subgroups of patients within a similar range of RD with different prognoses and subgroups of patients within different ranges of RD with similar prognoses.
THE ACTION OF CASCARA SAGRADA
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Septic shock
Authors: W. Schumer
Journal: JAMA (1979)

A 42-YEAR-OLD woman is admitted to the hospital complaining of epigastric pain of five days' duration, radiating to the lower quadrant and associated with nausea, vomiting, and constipation. The pain, originally severe, relents after 24 hours and then becomes generalized throughout the abdomen and is associated with chills and fever. A physician finds rigidity, tenderness, rebound tenderness, and a tender mass in the right lower quadrant; the rectal examination shows peritoneal bogginess with notable right lower quadrant tenderness. At the time of admission the patient's temperature is 39.4 °C. She complains of chills. The skin is flushed and warm. The blood pressure (BP) is 120/80 mm Hg. A course of antibiotics is begun. Later the BP increases to 160/70 mm Hg, and the pulse rate and urinary output decrease. Then the skin becomes cold and clammy, the BP decreases to 60/0 mm Hg, and the pulse rate increases to 150
Histopathology of hepatitis E is associated with patients’ immune status and preexisting liver condition
Authors: Daniela Lenggenhager, Samuel Pawel, Hanna Honcharova-Biletska, Katja Evert, Juergen Wenzel, Matteo Montani, Eva Furrer, Montserrat Fraga Christinet, Darius Moradpour, Christine Sempoux, Achim Weber
Journal: Journal of Hepatology (2020)
The USA's dangerous driving culture
Authors: None The Lancet
Journal: The Lancet (2016)

July 4 is a time for celebration in the USA, but this day is also ranked the deadliest of the year for driving-related fatalities. On July 6, the US Centers for Disease Control and Prevention (CDC) released a report on motor vehicle deaths in the USA compared with 19 other high-income countries including the UK. They analysed data compiled by WHO and the Organisation for Economic Co-operation and Development on crash deaths in 2000 and 2013. On a positive note, the death rate from crashes in 2013 in the USA was 31% lower than the rate in 2000.
<i>ALK</i> Mutants Show Differential Response to Crizotinib
Journal: Cancer Discovery (2011)

Abstract Major finding: F1174L-mutated ALK shows reduced sensitivity to crizotinib inhibition. Mechanism: The F1174L mutation enhances the ATP-binding affinity of ALK. Impact: Patients with F1174L-mutated ALK may benefit from higher crizotinib doses.
Hernia. Its Anatomy, Etiology, Symptoms, Diagnosis, Differential Diagnosis, Prognosis and Operative Treatment.
Journal: JAMA (1924)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Growth Abnormalities in the Population Exposed in Utero and Early Postnatally to Polychlorinated Biphenyls and Dibenzofurans
Authors: Yueliang L. Guo, George H. Lambert, Chen-Chin Hsu
Journal: Environmental Health Perspectives (1995)

This article reviews the findings in children exposed to various levels of polychlorinated biphenyls (PCBs) and related compounds in utero and early postnatally.Yu-Cheng ("oil-disease") mothers were Taiwanese women exposed to PCBs and their heat-degradation products from the ingestion of contaminated rice oil in 1979.Children of these mothers were born growth retarded, with dysmorphic physical findings, and delayed cognitive development compared with unexposed children.In this article, findings in Yu-Cheng children born between 1978 and 1985 are summarized and compared with two other well-documented cohorts of children prenatally exposed to different levels of PCBs.Results of the investigation in Yu- Cheng children will provide important information about the toxicities, health effects, and mechanisms of PCB/PCDF exposure and demonstrate that the developing human is more sensitive than the adult to the toxic effects of these chemicals.-
Irreversible Binding of Chlorinated Ethylenes to Macromolecules
Authors: H. M. Bolt, J. G. Filser
Journal: Environmental Health Perspectives (1977)

Rats have been exposed in a closed system to the chlorinated ethylenes vinyl chloride and trichloroethylene and to carbon tetrachloride as a reference compound. Data of uptake of the compounds, of urinary excretion of metabolites, and of exhalation after exposure show that the chlorinated ethylenes are metabolized much faster than carbon tetrachloride, probably due to their common ethylene structure. To eliminate differences in uptake, calculation of metabolites of the three compounds in tissues was based on the amount actually taken up by the animals. Vinyl chloride, trichloroethylene, and carbon tetrachloride showed irreversible binding of metabolites to tissue proteins, mainly of the liver. Irreversible protein binding of either of these compounds ranged within the same order of magnitude, if related to the amount of compound which had been taken up. Also, no differences in the relative portion of irreversibly bound metabolites were found after exposure to different atmospheric concentrations of the three compounds. As already shown for vinyl chloride, trichloroethylene is metabolized in vitro by rat liver microsomes in presence of NADPH-regenerating system to intermediates that irreversibly bind to proteins. Albumin (bovine and rabbit) was a preferred target for binding. In contrast to vinyl chloride, significant irreversible binding of trichloroethylene metabolites also occurred to non-SH-proteins (γ-globulin, concanavalin A) and to polylysine. Hence it should be inferred that, unlike vinyl chloride, trichloroethylene metabolites not only bind to sulfhydryl groups but also, to a lesser extent, to free amino groups of proteins.
LUNG TRANSPLANTATION
Authors: JAMES D. HARDY
Journal: Annals of Internal Medicine (1967)

Letters and Comments1 April 1967LUNG TRANSPLANTATIONJAMES D. HARDY, M.D.JAMES D. HARDY, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-66-4-815 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editor: I have read with interest and definite surprise the recent (November 1966) editorial by Robin and Cross entitled "Lung Transplantation—Past, Present, and Future." A first reaction was to offer another editorial in which the dialogue would be extended and brought into balance. However, one finds that the ANNALS has devoted a remarkable amount of space to similar editorials over the past several years.The authors have examined the subject of lung transplantation with considerable assurance. Yet, a brief search of their published titles has disclosed no research in the transplantation field—genetics, immunology, pathology, or operative technique. If... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Department of Surgery University of Mississippi Medical Center Jackson, Miss. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 April 1967Volume 66, Issue 4Page: 815-816KeywordsForecastingImmunologyLung transplantationTransplantation Issue Published: 1 April 1967 PDF DownloadLoading ...
American Journal of Surgery, New York
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
ASSOCIATION NEWS.
Authors: I. N. Love
Journal: JAMA (1894)

<b>The Association Train</b>will leave Chicago Monday, May 28, via Santa Fe R. R., Rio Grande Western, and Southern Pacific, for San Francisco via Denver, Colorado Springs, Leadville, Manitou, Glenwood Springs, Salt Lake, Ogden, Truckee and Sacramento. Returning, after the meeting, the train will pass through Sacramento and Northern California to Portland, thence east by way of the Northern Pacific R. R. to St. Paul. C. M. &amp; St.P. R. St. Paul to Chicago. A stop over at Yellowstone National Park for those who desire it has been arranged, and it has been understood that at several places on the journey there will be short stops. President Hibberd's party in a special car join the train at Chicago, and the St. Louis party are expected to join at Kansas City. From all points east and south, concentrating on this train should be effected at Chicago and St. Louis. For all