tbuckley/cabot-search huggingface dataset:
Inhibition of Chemically Induced Mammary Carcinogenesis in Rats by Long-Term Exposure to Butylated Hydroxytoluene (BHT): Interrelations Among BHT Concentration, Carcinogen Dose, and Diet234
Authors: L. A. Cohen, K. Choi, S. Numoto, M. Reddy, B. Berke, J. H. Weisburger
Journal: JNCI Journal of the National Cancer Institute (1986)

Journal Article Inhibition of Chemically Induced Mammary Carcinogenesis in Rats by Long-Term Exposure to Butylated Hydroxytoluene (BHT): Interrelations Among BHT Concentration, Carcinogen Dose, and Diet Get access L. A. Cohen, L. A. Cohen Search for other works by this author on: Oxford Academic PubMed Google Scholar K. Choi, K. Choi Search for other works by this author on: Oxford Academic PubMed Google Scholar S. Numoto, S. Numoto Search for other works by this author on: Oxford Academic PubMed Google Scholar M. Reddy, M. Reddy Search for other works by this author on: Oxford Academic PubMed Google Scholar B. Berke, B. Berke Search for other works by this author on: Oxford Academic PubMed Google Scholar J. H. Weisburger J. H. Weisburger Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 76, Issue 4, April 1986, Pages 721–730, https://doi.org/10.1093/jnci/76.4.721 Published: 01 April 1986 Article history Received: 01 April 1985 Revision received: 04 October 1985 Accepted: 12 November 1985 Published: 01 April 1986
Postpartum Meningitis
Authors: Fred Allison
Journal: JAMA (1964)

<h3>To the Editor:—</h3> Dr. Currier and I agree with the observation by Dr. Trimble (<i>JAMA</i><b>189</b>:828 [Sept 14] 1964) concerning our reply to the question entitled "Postpartum Meningitis" (<i>JAMA</i><b>183</b>:909 [March 9] 1963). The congenitally small, nonfunctioning kidney and the chronic bilateral pyelonephritis were important aspects of the patient's medical problem, but we believe they did not have direct bearing on the neurological disease. The relationship of chronic renal insufficiency to refractory anemia is well recognized and may be of significance, but no information pertaining to kidney function was available to clarify this point. Recurrent or chronic pneumonia could have contributed just as well to the problem, since the body temperature of the patient was elevated at times. Finally, poor caloric intake with undernutrition might add to an anemic process. In difficult problems of infection, as represented by this case, it may not be possible to explain all
The Medical Muse, Grave and Gay.
Journal: JAMA (1896)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Scientific Exhibits and Posters Technical Exhibits
Authors: Felix Sabates, King Lee, Matthew Ziemianski, Gary Gallimore, Kansas City, Lawrence Singerman, Jerry Shields, Kurt Gitter, New Orleans, David Orth, Olympia Fields, Howard Schatz, Eleanor Faye, Robert Silver, Munro Levitzy, Judith Gurland, Bruce Rosenthal, Clare Hood, Elisabeth Stern, New York, Ophthalmic Photography, Kenneth Julian, Ogden Frazier, Santa Ana, Thomas Egnatz, Bruce Morris, Barry Maltzinan, Donald Cinotti, Peter Evans, Thomas Kirby, Robert Christensen, Richard Augustine, Alice Liska, Nancy Weber
Journal: Ophthalmology (1981)
Book Review Neurology . By Roy R. Grinker, M.D. With the assistance of Norman A. Levy, M.D. With a chapter on brain tumors by Paul C. Bucy, M.D. Third edition. 4°, cloth, 1136 pp., with 416 illustrations. Springfield, Illinois: Charles C Thomas, 1943. $6.50.
Journal: New England Journal of Medicine (1943)
Exercise intensity and longevity in men. The Harvard Alumni Health Study
Authors: I. M. Lee
Journal: JAMA (1995)

<h3>Objective.</h3> —To examine the independent associations of vigorous (≥6 resting metabolic rate [MET] score) and nonvigorous (&lt;6 MET score) physical activity with longevity. <h3>Design.</h3> —Prospective cohort study, following up men from 1962 or 1966 through 1988. <h3>Setting/Participants.</h3> —Subjects were Harvard University alumni, without self-reported, physician-diagnosed cardiovascular disease, cancer, or chronic obstructive pulmonary disease (n=17 321). Men with a mean age of 46 years reported their physical activities on questionnaires at baseline. <h3>Main Outcome Measure.</h3> —All-cause mortality (3728 deaths). <h3>Results.</h3> —Total energy expenditure and energy expenditure from vigorous activities, but not energy expenditure from nonvigorous activities, related inversely to mortality. After adjustment for potential confounders, the relative risks of dying associated with increasing quintiles of total energy expenditure were 1.00 (referent), 0.94, 0.95, 0.91 and 0.91, respectively (<i>P</i>[trend]&lt;.05). The relative risks of dying associated with less than 630,630 to less than 1680,1680 to less than 3150,3150 to less than 6300, and 6300 or more kJ/wk expended on vigorous activities were 1.00 (referent), 0.88, 0.92, 0.87, and 0.87, respectively (<i>P</i>[trend]=.007). Corresponding relative risks for energy expended on nonvigorous activities were 1.00 (referent), 0.89,1.00,0.98, and 0.92, respectively (<i>P</i>[trend]=.36). Analyses of vigorous and nonvigorous activities were mutually adjusted. Among men who reported only vigorous activities (259 deaths), we observed decreasing age-standardized mortality rates with increasing activity (<i>P</i>=.05); among men who reported only nonvigorous activities (380 deaths), no trend was apparent (<i>P</i>=.99). <h3>Conclusions.</h3> —These data demonstrate a graded inverse relationship between total physical activity and mortality. Furthermore, vigorous activities but not nonvigorous activities were associated with longevity. These findings pertain only to allcause mortality; nonvigorous exercise has been shown to benefit other aspects of health. (<i>JAMA</i>. 1995;273:1179-1184)
Calcium deposits on IUDs may play role in infections
Authors: E. R. Gonzalez
Journal: JAMA (1981)

Of the more than 1 million intrauterine device (IUD) users in the United States, some 8,000 to 25,000 may get severe pelvic inflammatory disease (PID), including pelvic actinomycosis. But why? Answers to the conundrum are emerging piecemeal—mainly from the ongoing examination of used IUDs. Waldemar Schmidt, MD, PhD, one of the investigators involved in this effort, has now collected some 80 IUDs both from infected women and from women who had their devices removed because they wished to bear children. At the recent meeting of the International Academy of Pathology's United States—Canadian Division, held in Chicago, Schmidt presented information on 20 of these IUDs, all removed from women with pelvic actinomycosis. The most provocative new finding, he announced, was the presence of calcium deposits on the devices. Previously, Schmidt had noted that the IUD appears to change its microenvironment and that, reciprocally, the endometrium induces changes in the IUD
THE NEW HYGIENE.
Journal: JAMA (2006)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 183: Mortality in children with Kawasaki disease: 20 years of experience from a tertiary care centre in North India.
Authors: Sagar B Bhattad, Anju Gupta, Manojkumar Rohit, Deepti Suri, Amit Rawat, Surjit Singh
Journal: Circulation (2015)

Background: Kawasaki disease (KD) is a common vasculitic disorder of childhood. Reported mortality in KD in the West is 0.08 %. We report clinical profile of 4 children who succumbed to KD during 1994-2014 at Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research Centre, Chandigarh, India. To the best of our knowledge, this is the first report on mortality in KD from any developing nation. Objectives: To study the clinical and laboratory profile of 4 children with KD who died at our centre. Methods: During the period 1994-2014, a total of 415 children were diagnosed to have KD based on American Heart Association criteria. M:F ratio was 1.9:1 and 96 children were aged 2 years or less. Children with KD received 2 g/kg of intravenous immunoglobulin (IVIg) and 50-80 mg/kg/day of aspirin initially and 3-5 mg/kg/day later. 2-D echocardiography was done once during the acute phase and then 6-8 weeks later on follow up. 4 amongst these died and their details were analysed by study of clinical records. Results: We report 4 deaths (2 boys, 2 girls) in this cohort of 415 children with KD. All 4 were below 2 years of age and had had significant delays in diagnosis and referral (Table). Symptomatic myocarditis was noted in 2 children, while 2 of them had thrombocytopenia. Conclusion: We report a mortality of about 1% in children with KD. Delays in diagnosis and referral contributed significantly to this mortality.
Indications for liver and brain scans. Screening tests for patients with oat cell carcinoma of the lung
Authors: R. E. Wittes
Journal: JAMA (1977)

From 1973 to 1975, scans of the liver and brain as routine screening procedures were performed on patients with oat cell carcinoma of the lung at the Memorial Sloan-Kettering Cancer Center. Normal test results were observed in 20 of 21 and 32 of 35 patients who showed no clinical evidence of involvement of the liver and brain. Only one scan in 21 and one in 35 yielded new information concerning possible organ involvement. We concluded that scans of the liver and brain are not useful methods of screening the patient with no clinical evidence of oat cell carcinoma. (<i>JAMA</i>238:506-507, 1977)
From the National Institutes of Health
Authors: J. B. Wyngaarden
Journal: JAMA (1986)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Treatment of patients with cirrhosis and refractory ascites using LeVeen shunt with titanium tip: Comparison with therapeutic paracentesis*1
Authors: A GINES
Journal: Hepatology (1995)

It has recently been suggested that insertion of a titanium tip at the venous end of the LeVeen shunt drastically reduces the rate of shunt obstruction. To assess whether the LeVeen shunt with titanium tip improves the results obtained with therapeutic paracentesis, 81 patients with cirrhosis and refractory ascites were randomly assigned to therapy with paracentesis plus intravenous albumin (42 patients) or LeVeen shunt with titanium tip (39 patients). If patients were readmitted for ascites during follow-up, those in the first group were treated with paracentesis, and those in the LeVeen shunt group by the insertion of a new valve or a new shunt if obstruction was demonstrated. During first hospitalization, both treatments were equally effective in removing ascites. Complications were similar in both groups except for a higher rate of severe bacterial infection in the LeVeen shunt group. The mean duration of hospitalization was shorter in the paracentesis group than in the shunt group. During follow-up, the total number of readmissions and the number of readmissions for ascites were higher in the paracentesis group than in the shunt group (252 vs. 99, P < .001; and 193 vs. 43, P < .001, respectively). The total time in hospital, however, was similar (38 ± 38 vs. 39 ± 43 days, P = NS). Three patients had obstruction of the shunt during first hospitalization and 14 patients had a total 422 obstructions during follow-up. Long-term survival was similar in both groups. The insertion of a titanium tip at the venous end of the LeVeen shunt does not prevent obstruction. The LeVeen shunt with titanium tip does not provide significant improvement over therapeutic paracentesis in the management of cirrhotic patients with refractory ascites.
Immunization Recommendations in Young Adulthood
Journal: JAMA (1988)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
"MODIFIED SALICYLIC ACID" AND "SAMARIN"
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
CAN THYROGLOBULIN MEASUREMENTS REPLACE I-131 SCANS IN THE FOLLOWUP OF THYROID CANCER PATIENTS?
Authors: Lalitha Ramanna, Alan Waxman, Nancy Sensel, Michael Brachman, Doina Tanasescu, Daniel Berman, Glenn Braunstein, Boris Catz
Journal: Clinical Nuclear Medicine (1983)

Ramanna, Lalitha; Waxman, Alan; Sensel, Nancy; Brachman, Michael; Tanasescu, Doina; Berman, Daniel; Braunstein, Glenn; Catz, Boris Author Information
Online support group helps patients live with, learn more about the rare skin cancer CTCL-MF
Authors: L. Lamberg
Journal: JAMA (1997)

A WOMAN and her husband went to see their family physician after her dermatologist told her that she had cutaneous T-cell lymphoma (CTCL), a form of lymphoma that usually starts in the skin. "Our family physician was not familiar with the disease (which often progresses slowly)," the husband wrote members of an online support group for people with CTCL, "and hearing only the lymphoma part, gave her 6 months to a year to live. It took us a month, and the finding of this group, to sort out the truth." Online support groups, as this message suggests, can give patients and their families practical information as well as reassurance that they need not face their illness or disability alone. Although these groups function much like face-to-face groups in the community, they meet 24 hours a day, enabling participants to read or post messages at any time. The frequent exchanges commonly
Novel Targets for Lung Cancer Therapy: Part II
Authors: Grace K. Dy, Alex A. Adjei
Journal: Journal of Clinical Oncology (2002)

ABSTRACT: Lung cancer is the second most common form of cancer in the United States, and although it accounts for 15% of all cancers, it is the most lethal, accounting for approximately 28% of cancer deaths. In 2002, it is estimated that 177,000 new cases of lung cancer will be diagnosed in the United States, and an estimated 160,000 men and women will die from the disease. This mortality rate is greater than that attributable to colorectal, breast, and prostate cancer combined. Systemic treatments for lung cancer with standard chemotherapy agents are still relatively ineffective. Agents targeting novel proliferative and survival pathways in lung cancer are needed to improve treatment outcomes. In recent years, numerous agents inhibiting aberrant processes in tumor cells have undergone clinical evaluation. This review is the second of a two-part series that summarizes pertinent preclinical and clinical information on novel drugs that target critical abnormalities in lung cancer. In this article, agents that were developed to inhibit various aspects of tumor protein trafficking and protein degradation, cell cycle regulation, angiogenesis, and antigenicity are described. Future approaches to treatment are suggested.
Diseases of the Colon and Rectum, Philadelphia
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Monozygotic twins with chronic lymphocytic thyroiditis. (Hashimoto's disease)
Authors: M. T. Diamond
Journal: JAMA (1966)

THE ETIOLOGY of chronic lymphocytic thyroiditis (Hashimoto's disease) is unknown. The theory that an autoimmune process is related to its pathogenesis was advanced by Roitt and co-workers<sup>1</sup>when they demonstrated several types of antibody against the thyroid in the sera of patients with this disease. The finding of thyroid antibodies in the relatives of patients with chronic lymphocytic thyroiditis<sup>2</sup>has suggested to some the possibility of genetic mechanisms acting in its causation, and the diagnosis of the disease in several members of the same family is considered compatible with this theory. Interest in this question of genetic predisposition increased with the demonstration of the disease in monozygotic female twins. Five sets of identical twins with chronic lymphocytic thyroiditis have been reported in the world literature.<sup>3-6</sup>A sixth pair is now described. <h3>Report of Cases</h3> A pair of 65-year-old female uniovular twins have been followed up for the
Hyperthermia
Authors: Jane F. Desforges, Harvey B. Simon
Journal: New England Journal of Medicine (1993)

Body temperature, like other fundamental aspects of human biology, is closely regulated by intricate control mechanisms. These homeostatic controls allow body temperature to display a predictable diurnal rhythmicity, increasing from a nadir of about 36 °C in the early morning to approximately 37.5 °C in late afternoon1. A variety of disorders can elevate body temperature; those resulting from thermoregulatory failure are properly called hyperthermia, whereas those resulting from intact homeostatic responses are categorized as fever.ThermoregulationBody temperature is a balance between heat production and heat dissipation. Heat is generated internally as a byproduct of all metabolic processes; when . . .