tbuckley/cabot-search huggingface dataset:
Preventive Medicine
Authors: George L. Fite
Journal: JAMA (1967)

The editors declare this 44-part, many authored text to be primarily concerned with the needs of the medical student. The three main divisions into methods, etiologies, and prevention in practice include catchbasins for the socioeconomics of medicine and industrial and legal medicines. Although the traditional title,<i>Preventive Medicine</i>, satisfies the proposed market, a more accurate title would be, "The Epidemiologist Looks at All Aspects of Medicine and Its Practice in the United States, While Simultaneously Indoctrinating the Reader in Methodology." This is as much as ten men could absorb in ten years. In the past decade, preventive medicine has so added and subtracted from its curriculum that its teaching has been revised from roots to leaf tips. This text has subtracted all the classical epidemiology of individual infectious diseases; sanitary engineering is dropped—to adjust the balance, the text has added public health aspects of aging populations, social welfare, and governmental
BELGIUM
Journal: JAMA (1928)

<h3>The Belgium Medical Convention</h3> This year, the annual (eighth) session of the Belgium Medical Week, or the Journées médicales belges de Bruxelles, will be held in April, two months earlier than usual. The change was made in order to afford the conventionists an opportunity to attend the flower exposition that is held in Ghent every three years. Among others the following well known men have indicated a willingness to participate: Drs. Gley, Donati, Damas Mora, Pautrier, Söderbergh, Bordier, Egas Moniz, Bastos, Noël Fiessinger, M. P. Weill, Sanvenero-Rosselli, P. Nolf, E. Renaux, J. Duesberg, D'Hollander, E. Zunz. The convention will open April 22, and the inaugural address will be delivered by the prime minister, M. Henry Jasper, on the subject of the council on medical ethics (<i>ordre des médecins</i>). <h3>Study Scholarships for the Congo</h3> The minister of colonies has established four study scholarships for the benefit of young physicians desiring to
ANOTHER INSANITARY CONDITION.
Journal: JAMA (1905)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Fluid Balance: A Clinical Manual
Journal: JAMA (1952)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Correction: Hsp27 Promotes Insulin-Like Growth Factor-I Survival Signaling in Prostate Cancer via p90Rsk-Dependent Phosphorylation and Inactivation of BAD
Journal: Cancer Research (2011)

In this article (Cancer Res 2010;70:2307–17), which was published in the March 15, 2010 issue of Cancer Research (1), the following funding support is not included:Pacific Northwest Prostate SPORE NCI CA097186.
Recouvrement pariétal par voie endoscopique en prévention des saignements après une dissection sous-muqueuse (DSM) endoscopique: un essai prospectif multicentrique randomisé et contrôlé
Journal: Endoscopy (2019)

Le saignement post-DSM gastrique est l'un des événements indésirables les plus graves et par conséquent, leur prévention est une question importante sur le plan clinique. Il existe actuellement deux méthodes efficaces de prévention des saignements: les inhibiteurs de la pompe à protons (IPP) pour favoriser la cicatrisation de l'ulcère “iatrogène” et la coagulation des vaisseaux visibles. Plusieurs études ont montré que l'utilisation d'agents anticoagulants et la taille de la zone de résection (≥ 40 mm) sont des facteurs de risque de saignements post-DSM.
Manuscripts Approved for JNCI, March 10 to April 10, 1963
Journal: JNCI Journal of the National Cancer Institute (1963)

Journal Article Manuscripts Approved for JNCI, March 10 to April 10, 1963 Get access JNCI: Journal of the National Cancer Institute, Volume 30, Issue 5, May 1963, Page 1093, https://doi.org/10.1093/jnci/30.5.1093-a Published: 01 May 1963
Highlights from this issue
Journal: Thorax (2018)

The Triumvirate 'I have seen my death!'Wilhelm Röntgen took the first X-ray picture in 1895 in his laboratory in Munich: an X-ray of the hand of his wife Anna Bertha.When she saw the skeletal image she is said to have exclaimed 'I have seen my death!'In 1901, Röntgen was awarded the first Nobel prize in physics.His 'röntgenograms' ushered in a new era in imaging with many diagnostic and prognostic applications.One such prognostication is highlighted by Warren and colleagues in this month's journal (see page 840).They describe the development and validation of the Radiographic Assessment of Lung Oedema (RALE) score.In a very practical way, they scored chest X-rays and then weighed the lungs of 72 transplant donors to quantify lung fluid.They then validated the score against clinical data in 172 patients with acute respiratory distress syndrome (ARDS).In the validation cohort, RALE score predicted survival.So predictions of death, using X-rays, are not confined to Röntgen's wife!
Oral antifungal agent effective even for widespread infections
Authors: W. A. Check
Journal: JAMA (1980)

Evidence continues to amass on the effectiveness of the investigational drug ketoconazole in the treatment of both superficial and disseminated fungal infections (<i>JAMA</i>[MEDICAL NEWS] 1980;243:12). Amphotericin B also is efficacious, according to investigators, but chronic fungal infections often require long-term drug administration to prevent relapse. The advantage of ketoconazole is that it is an oral agent, in contrast to amphotericin B, which must be given intravenously and therefore necessitates a lengthy and expensive hospital stay. The most recent report, involving 12 consecutive patients with chronic mucocutaneous candidiasis, was given at the 20th Interscience Conference on Antimicrobial Agents and Chemotherapy in New Orleans. In a double-blind trial, Eskild A. Petersen, MD, and colleagues at the National Institute of Allergy and Infectious Diseases (NIAID) randomly allocated the patients to treatment with ketoconazole or an oral placebo. All but one had been afflicted for more than six years. The subjects were continued
PROCEEDINGS OF THE CHICAGO SESSION
Journal: JAMA (1952)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Developmental Care for Very Low-Birth-Weight Infants
Authors: Samuel Sepkowitz
Journal: JAMA (1995)

<h3>To the Editor.</h3> —In the study by Dr Als and colleagues,<sup>1</sup>only 17% (3/18) of the control group were black infants while 40% (8/20) of the experimental group, that is, those who received individualized developmental care, were black infants. This difference in distribution was dismissed as not significant (χ<sup>2</sup>, 2.51;<i>P</i>=.11). However, black, very low-birth-weight infants have lower mortality rates than white newborns of comparable weights nationally, and when compared internationally, the black, very small newborn also has lower mortality rates than those of other industrialized countries.<sup>2</sup>Als et al have aggregated their black and white patients, ignoring longstanding epidemiological evidence that "quality of medical care cannot be evaluated in a meaningful way using aggregated data."<sup>3</sup> Not surprisingly, lower mortality rates are associated with lower morbidity. Black premature infants have significantly less hyaline membrane disease than white premature infants. In addition, the disease is less
Sulfonamide Crystals
Authors: Kanin Thammavaranucupt, Ittikorn Spanuchart
Journal: New England Journal of Medicine (2021)

Decreased urinary output developed in a 42-year-old man who was receiving trimethoprim–sulfamethoxazole for Pneumocystis jirovecii pneumonia. Urine microscopy revealed fan-shaped crystals. A diagnosis of sulfonamide-crystal–induced acute kidney injury was made.
PROMOTION WITH LOSS OF INCOME
Authors: None K. O. P.
Journal: JAMA (1918)

<h3>To the Editor:</h3> —In your information to prospective medical officers regarding pay, commutation of quarters for dependents, etc., there is one contingency, one throw of the dice, that may knock out these calculations. I entered the service sixteen months ago. I am 45 years old and have a wife and five children. I was at San Francisco and Camp Fremont as a first lieutenant up to last month. Since April 15 I have been allowed commutation for my family in the state of Washington, which brought my check up to $203.28 a month. I was sent to the Canal Zone and found on arrival I was a captain. I also found that there are quarters "to burn" at all the camps here. It will take between $400 and $500 to move my family down here any way I figure it, as they would have to come to New Orleans, 3,300
Questions and Answers
Journal: JAMA (1985)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
J Laboratory &amp;amp; Clinical Medicine, St. Louis
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Effects of Inhaled Acid Aerosols on Lung Mechanics: An Analysis of Human Exposure Studies
Authors: Mark J. Utell
Journal: Environmental Health Perspectives (1985)

There exist significant gaps in our understanding of human health effects from inhalation of pollutants associated with acid precipitation. Controlled clinical studies examine effects of criteria pollutants almost exclusively by assessing changes in lung mechanics. One constituent of acid precipitation, sulfuric acid aerosols, has been shown to induce bronchoconstriction in exercising extrinsic asthmatics at near ambient levels. These asthmatics may be an order of magnitude more sensitive to sulfuric acid aerosols than normal adults. More recently, a second component nitrogen dioxide has been observed to provoke changes in lung mechanics at progressively lower concentrations. To date, virtually no data exist from clinical exposures to acidic aerosols for subjects with chronic obstructive pulmonary disease.
THE "CAMP GHOST" AT CAMP WIKOFF.
Journal: JAMA (1998)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
LETTER FROM LONDON.
Authors: None G. O. M.
Journal: JAMA (1889)

(FROM OUR OWN CORRESPONDENT.) Some Interesting Facts about the Brain—Poisoning by Arsenic—The Overcrowding of the Medical Profession—Statistics of Admission to Scottish Lunatic Asylums—The Mode of Treatment at Aix les Bains—The Anglo-American Vienna Medical Association—Miscellaneous Notes. There has been published the result of some measurements of the heads of students in the Cambridge University, showing that although it is pretty well ascertained that in the masses of the population the brain ceases to grow after the age of 19 or even earlier, it is by no means so with University students, and that the men who obtain University honors have larger brains than the average. Further careful experiments show that the brains of human beings change in size. Taken at different times in the same individual the length of the head varied 11/10 inch, the width 1/5 inch, and the length as much as ½ inch. The variations were not due
Biochemical Factors in Etiology of Carcinoma of Bladder
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Nitroprusside Dose
Journal: JAMA (1977)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Error in End Matter Disclaimer
Journal: JAMA Network Open (2019)

Akbar K. Waljee, MD, MSc; Beth I. Wallace, MD, MS; Shirley Cohen-Mekelburg, MD, MS; Yumu Liu, MS; Boang Liu, MS; Kay Sauder, BS; Ryan W. Stidham, MD; Ji Zhu, PhD; Peter D. R. Higgins, MD, PhD, MSc
A phase I trial of imatinib mesylate in combination with chlorambucil in previously treated chronic lymphocytic leukemia patients
Authors: J. P. Hebb, S. Assouline, C. Rousseau, R. Aloyz, P. DesJardins, S. Caplan, L. Panasci
Journal: Journal of Clinical Oncology (2008)

18021 Background: Treatment of chronic lymphocytic leukemia (CLL) with alkylating agents such as chlorambucil (CLB) eventually leads to resistance. One mechanism of resistance involves the repair of drug-induced DNA interstrand cross links, which is mediated, in part, by the phosphorylation of Rad51 by c-abl. Imatinib inhibits c-abl activity, and thus may sensitize CLL cells to CLB through inhibition of c-abl mediated DNA-repair pathways. In vitro studies have shown a synergistic effect of imatinib on CLB-mediated cytotoxicity in CLL lymphocytes. On this basis, a phase I clinical study was initiated combining CLB and imatinib for the treatment of relapsed and refractory CLL to determine the recommended phase II dose(RP2D) and toxicities. Preliminary efficacy was also assessed. Methods: Patients with relapsed or refractory CLL were eligible if they met indications for treatment. Three patients were treated per dose level unless dose limiting toxicity was observed in which case the cohort was expanded to include 6 patients. Three dose levels were included corresponding to imatinib doses of 300, 400, or 600 mg/day. Chlorambucil dose was 8 mg/m2 in all patients. Imatinib was given on days 1–10 and CLB on days 3–7, repeated every 28 days for up to 6 cycles. Results: Eleven patients have been enrolled to date, 3 at dose level 1, 3 at level 2, and 5 at level 3. There has been one dose-limiting toxicity at level 3 (grade 3 thrombocytopenia), and two severe adverse events (SAEs) - one at level 2 (pneumonia with respiratory failure) and one at level 3 (disseminated herpes). At present 4 of 11 patients have completed all 6 cycles. Dose level 3 has been expanded to 6 patients. The RP2D has not yet been determined. Ten patients were assessable for efficacy. There was one complete response (CR), and 3 patients with a partial response (PR) for an overall response rate of 40%. Two responders including the CR were previously treated with fludarabine, the other two had previous treatment with CLB alone. Median follow-up is 6 months. Conclusions: The combination of imatinib and CLB is well tolerated and shows evidence of efficacy. Ongoing work will clarify the RP2D with plans to move on to a phase II study. No significant financial relationships to disclose.