tbuckley/cabot-search huggingface dataset:
Lack of association between pertussis vaccination and symptoms of asthma and allergy
Authors: L. Nilsson
Journal: JAMA (1996)

<h3>To the Editor.</h3> —Previous reports<sup>1</sup>suggesting that pertussis vaccination considerably increases the risk for bronchial asthma in schoolchildren prompted us to add a structured interview to all the families in a double-blind study of per tussis vaccines to assess whether pertussis vaccination might influence symptoms in early childhood consistent with later development of allergic disease. Pertussis immunization elicits an IgE response in animals.<sup>2</sup>Children may also show pertussis IgE after pertussis infection and vaccination, but clinical consequences are unclear.<sup>3</sup>Retrospective data support a weak effect of pertussis infection on development of sensitization.<sup>4</sup> Since 1979, pertussis vaccination has not been included in the Swedish vaccine program. The Swedish Pertussis Vaccine Efficacy Trial 1<sup>5</sup>recruited 9829 infants born in 1992. The study was approved by the Human Research Ethics Committee of Karolinska Institute, Stockholm, Sweden. The study was performed double-blind, and three fourths of the infants were
Herpes simplex virus in idiopathic facial paralysis (Bell palsy)
Authors: K. K. Adour
Journal: JAMA (1975)

Sera from all 41 adult patients with idiopathic facial paralysis (Bell palsy) and 35 (85%) of 41 matched controls who had never had Bell palsy contained antibodies to herpes simplex virus (<i>P</i>&lt;.05). The frequency of antibodies to herpes zoster virus did not differ in patients and controls. A rise in antibody titer, indicating primary herpes simplex virus infection, was not found in these patients. That Bell palsy may be caused by reactivation of herpes simplex virus is suggested by (1) clinical, neurologic, laboratory, and immunologic similarities between idiopathic facial paralysis and known manifestations of reactivated herpes simplex virus infection, and (2) the known neurotropism of herpes simplex virus, including its presence in latent form in the trigeminal ganglia, and parallels with known facial paralysis due to varicella zoster virus, a closely related agent. The presence of antibodies to herpes simplex virus is the only common factor among the patients tested in this study. (<i>JAMA</i>233:527-530, 1975)
Jeanel's Emulsion--a Correction.
Journal: JAMA (1896)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Relative Physics
Authors: Brian W. Christman
Journal: Annals of Internal Medicine (2019)

Ad Libitum20 August 2019Relative PhysicsBrian W. Christman, MDBrian W. Christman, MDVanderbilt University, Nashville, Tennessee (B.W.C.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/M19-1101 Audio Reading - “Relative Physics” Audio. Michael A. Lacombe, MD, Annals Associate Editor, reads “Relative Physics” by Brian W. Christman, MD Your browser does not support the audio element. Audio player progress bar Step backward in current audio track Play current audio trackPause current audio track Step forward in current audio track Mute current audio trackUnmute current audio track 00:00/ SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Entropy doesn't just happen.Circumventing the orderEngendered by social librarians and statistical engineers,Requires energy.To assume that the vacuumed pile carpetsWhose parallel rows match the furrowed fields outside,Or the beige bathroom tiles, so cool even in August,Are poised for change shows poverty of thought.A system kept invariant accrues strata of inertia.Persuading intransigent masses must be done obliquelyTo nudge atoms from familiar orbits.Marilyn, at the counter, dispenses kindness with grace.... Author, Article, and Disclosure InformationAffiliations: Vanderbilt University, Nashville, Tennessee (B.W.C.)Corresponding Author: Brian W. Christman, MD; e-mail, brian.[email protected]gov. PreviousarticleNextarticle Advertisement Audio Reading - “Relative Physics” Audio. Michael A. Lacombe, MD, Annals Associate Editor, reads “Relative Physics” by Brian W. Christman, MD Your browser does not support the audio element. Audio player progress bar Step backward in current audio track Play current audio trackPause current audio track Step forward in current audio track Mute current audio trackUnmute current audio track 00:00/ FiguresReferencesRelatedDetails Metrics 20 August 2019Volume 171, Issue 4Page: 299KeywordsCoffeeEngineers ePublished: 20 August 2019 Issue Published: 20 August 2019 PDF downloadLoading ...
Abstract 3425: Prognostic significance of <i>BRMS1</i> promoter methylation in operable breast cancer
Authors: Maria Chimonidou, Efstathios Stathopoulos, Vasilis Georgoulias, Evi S. Lianidou
Journal: Cancer Research (2012)

Abstract Backround: Breast Cancer Metastasis Suppressor gene-1 (BRMS1) suppresses breast cancer metastasis in multiple experimental models by reducing solitary cell survival and inhibiting growth initiation. Loss of BRMS1 expression has been shown to predict reduced disease-free survival in subsets of breast cancer patients. The BRMS1 promoter region contains a promoter-associated CpG island (CGI) that encompasses the transcriptional start site.The aim of our study was to investigate the methylation status of BRMS1 in breast tumors (FFPES) of operable breast cancer patients and evaluate its prognostic significance. Patients and methods: Using methylation-specific PCR (MSP), we examined BRMS1 promoter methylation in 116 fixed paraffin-embedded tissues (FFPEs): 5 pairs of breast tumors and their surrounding non-cancerous tissues, 4 non-cancerous tissues, 10 benign breast tumors (fibroadenomas), 10 normal breast tissues and 82 breast tumors. All breast tumors were isolated from patients with operable breast cancer. Results: Methylation of BRMS1 promoter was observed in 0/19 (0%) noncancerous breast tissues, in 0/10 (0%) benign breast tumors (fibroadenomas) and in 31/82 (37.8 %) breast cancer tumors. During the follow-up period 22/82 (26.8%) patients relapsed and 20 (24.4%) patients died. BRMS1 methylation was detected in 13/22 (59.1%) patients that relapsed and in 12/20 (60.0%) of patients who died. Disease-free interval (DFI) and overall survival (OS) were significantly associated with BRMS1 promoter methylation (P=0.007). Conclusion: We show for the first time that BRMS1 promoter methylation status in FFPEs from operable breast cancer patients provides important prognostic information and merits to be further evaluated and validated in a larger cohort of patients. This finding is consistent with other studies that showed significant down-regulation of BRMS1 in some breast tumors, especially in metastatic disease, because of epigenetic silencing. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 103rd Annual Meeting of the American Association for Cancer Research; 2012 Mar 31-Apr 4; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2012;72(8 Suppl):Abstract nr 3425. doi:1538-7445.AM2012-3425
PSA Test Is Approved for Use in Conjunction With Digital Rectal Examination as Aid in Prostate Cancer Detection
Journal: JAMA (1994)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
REPLY: Re: Benefits and Risks of Screening Mammography for Women in Their Forties: a Statistical Appraisal
Authors: M. Napoli
Journal: JNCI Journal of the National Cancer Institute (1999)

In its conflict of interest forms, the Journal asks potential authors to identify any "financial connections, direct or indirect, or other situations that might raise the question of bias in the work reported or the conclusions, implications, or opinions stated-including pertinent commercial or other sources of funding for the individual author(s) or for the associated department(s). . .."In my opinion, some of Dr. Kopans' patents should have been listed as a note at the end of his Correspondence.My purpose in bringing this up is to ask the Journal editors (and the larger universe of medical journal editors) whether they agree.If so, then shouldn't Dr. Kopans' patents be noted at the end of all future mammography-related analyses in this and other journals?I would not have thought of asking this question but for the fact that Dr. Kopans has publicly raised charges of fraud (1) against some of his colleagues who disagree with his interpretation of the data supporting mammography screening for women in their forties.As for the questions raised concerning my organization's finances: The Center for Medical Consumers is a notfor-profit 501C3 organization.We do not have dues-paying members.Our library is open to the public at no charge.Our money comes from our newsletter, which is sold by subscription and in various formats to six information services.We also receive private donations, with the largest in the form of rent-free office space provided by the Judson Memorial Church on Washington Square.
Food Exposures to Lead
Authors: Albert C. Kolbye, Kathryn R. Mahaffey, John A. Fiorino, Paul C. Corneliussen, Charles F. Jelinek
Journal: Environmental Health Perspectives (1974)

Exposures to lead have emanated from various sources, including food, throughout human history. Occupational and environmental exposures (especially pica) appear to account for much of the identified human disease, however, food-borne exposures deserve further investigation. Lead residues in food can result from: biological uptake from soils into plants consumed by food animals or man, usage of lead arsenate pesticides, inadvertent addition during food processing, and by leaching them improperly glazed pottery used as food storage or dining utensils. Estimates of total dietary exposure should reflect frequency distribution data on lead levels in specific food commodities in relation to the quantities actually ingested by various sample populations to distinguish degrees of risk associated with particular dietary habits. Earlier estimates of average total dietary intake of lead by adults have been reported to range from above 500 μg/day downward with more recent estimates suggesting averages of 200 μg/day or lower. The strengths and weaknesses of these data are discussed along with analytical and sampling considerations. FDA programs related to food surveillance, epidemiology, and toxicological investigation are briefly described.
Geoffrey Spencer
Authors: Nicholas Hart, Margaret Brainthwaite
Journal: BMJ (2019)

Thank you for your interest in spreading the word about The BMJ.NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address. Username * Your Email * Send To * You are going to email the following Geoffrey Spencer Your Personal Message CAPTCHA This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
La educación y el cuidado de los excepcionales. Síntesis de la labor que se realiza en los Estados Unidos en beneficio de los niños y adultos que se apartan de lo normal
Journal: JAMA (1942)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A SELF-CONFESSED FRAUD.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
HIV/AIDS Among Racial/Ethnic Minority Men Who Have Sex With Men—United States, 1989-1998
Journal: JAMA (2000)

In the United States, racial/ethnic minority populations account for an increasing proportion of acquired immunodeficiency syndrome (AIDS) cases, including cases among men who have sex with men (MSM) (1). This report presents recent trends in AIDS incidence and deaths among MSM who belong to racial/ethnic minority populations, and compares data on human immunodeficiency virus (HIV) diagnoses with AIDS diagnoses during 1996-1998 among racial/ethnic minority MSM in the 25 states that have conducted confidential HIV surveillance and AIDS case surveillance since 1994. The findings indicate that among MSM, non-Hispanic black and Hispanic men accounted for an increasing proportion of AIDS cases and had smaller proportionate declines in AIDS incidence and deaths from 1996 to 1998. Of HIV and AIDS diagnoses among racial/ethnic minority MSM, the proportion who are young (aged 13-24 years) is higher than among white MSM.
银屑病患者严重感染的风险会增加吗?
Journal: British Journal of Dermatology (2021)

银屑病是一种慢性炎症性皮肤疾病, 它与糖尿病和肥胖症 (称为合并症) 等其他疾病相关 (关联) , 而这些疾病反过来又会增加感染的风险。银屑病患者的一个担忧是, 银屑病本身 (而不是合并症) 是否与严重感染的风险增加有关。严重感染是指任何严重到足以导致住院的感染。
481TiP Checkmate 722: A phase 3 trial of nivolumab with chemotherapy or ipilimumab vs chemotherapy in epidermal growth factor receptor (EGFR)-mutation, T790M-negative stage IV or recurrent non-small cell lung cancer (NSCLC) after EGFR tyrosine kinase inhibitor (TKI) therapy
Authors: K. Nakagawa, J.C-H. Yang, K. Park, Y. Ohe, Y-L. Wu, J. Gainor, A. Blackwood-Chirchir, R. Yang, I-F. Chang, T. Mok
Journal: Annals of Oncology (2016)
BACILLUS DYSENTERIÆ IN THE SUMMER DIARRHEAS OF INFANTS.
Journal: JAMA (1904)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Gastrointestinal bleeding
Authors: A. Kassem
Journal: Endoscopy (2006)

Interest in technical developments related to small-bowel imaging has been reflected in the number of abstracts dealing with the use of capsule endoscopy and double-balloon enteroscopy in gastrointestinal bleeding; the enthusiasm is still growing. For peptic ulcer bleeding, the surprisingly still high rates of recurrent bleeding, in spite of technological advances, still motivates clinicians to study the various factors that may influence the outcome and determine the way in which centers can adhere to practices that are based on the best available evidence. Concerns relating to the outcome of glue injection for bleeding gastric varices appear to be unjustified so far. There are still uncertainties relating to the endoscopic diagnosis and treatment of gastric antral vascular ectasia, as reflected in some studies.
2017 AHA/ACC Focused Update of the 2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines
Authors: Rick A. Nishimura, Catherine M. Otto, Robert O. Bonow, Blase A. Carabello, John P. Erwin, Lee A. Fleisher, Hani Jneid, Michael J. Mack, Christopher J. McLeod, Patrick T. O’Gara, Vera H. Rigolin, Thoralf M. Sundt, Annemarie Thompson
Journal: Circulation (2017)

transcatheter aortic valve replacement ◼ tricuspid stenosis ◼ valvular heart disease AHA/ACC GUIDELINE ACC/AHA Task Force Members, see page e1180*Focused Update writing group members are required to recuse themselves from voting on sections to which their specific relationships with industry may apply; see Appendix 1 for detailed information.†ACC/AHA Representative.
Molecular and population genetic analyses of β‐Thalassemia in Turkey
Authors: G.O. Tadmouri, Ş. Tüzmen, H. Özçelik, A. Özer, S.M. Baig, E.B. Senga, A.N. Başak
Journal: American Journal of Hematology (1998)

In this report we describe the molecular analysis of 795 chromosomes derived from unrelated Turkish β-thalassemia and sickle cell anemia carriers identified in hematology clinics in Istanbul, Ankara, Izmir, Adana, and Antalya. The determination of the molecular pathology of 754 β-thalassemia and 42 abnormal hemoglobin genes and analysis of the frequency distribution in six distinct regions of Turkey was accomplished. The experimental strategy, based on PCR amplification of the β-globin gene, included dot-blot hybridization with 18 probes specific for the Mediterranean populations, denaturing gradient gel electrophoresis, and genomic sequencing. When the regional results are compared with the overall frequency of mutations in the country, it is observed that the frequencies in the western and southern parts of Turkey are in good accordance with the overall distribution, whereas the northern and eastern parts have a more region/population-specific profile with some rare mutations having a significantly high occurrence in these regions. Further evaluation of the data with respect to region- or population-dependent differences will contribute to a better understanding of the mechanisms leading to the marked genetic heterogeneity in Turkey, but could also be extremely valuable in facilitating rapid identification of mutations in families at risk for different hemoglobinopathies. Am. J. Hematol. 57:215–220, 1998. © 1998 Wiley-Liss, Inc.
Recommended Childhood Immunization Schedule—United States, January-June 1996
Journal: JAMA (1996)

In January 1995, the recommended childhood immunization schedule was published in MMWR following issuance by the Advisory Committee on Immunization Practices (ACIP), the American Academy of Pediatrics, and the American Academy of Family Physicians (1). This schedule was the first unified schedule developed through a collaborative process among the recommending groups, the pharmaceutical manufacturing industry, and the Food and Drug Administration. This collaborative process should assist in maintaining a common childhood vaccination schedule and enabling further simplification of the schedule. This notice presents the recommended childhood immunization schedule for January-June 1996 (Figure 1) to incorporate licensure of varicella zoster virus vaccine (Var) and recommendations for adolescent hepatitis B vaccination.