tbuckley/cabot-search huggingface dataset:
Interim CDC Recommendations for Folic Acid Supplementation for Women—August 1991
Journal: JAMA (1991)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Dermatology
Authors: J. S. Dover
Journal: JAMA (1991)

The practice of medicine in the 1990s has been profoundly changed by the human immunodeficiency virus (HIV) epidemic. Current estimates are that more than 1 million individuals in the United States are infected with the HIV, of whom 150 000 have the acquired immunodeficiency syndrome (AIDS). Most patients will develop dermatologic problems during their illness. We will discuss those cutaneous diseases that provide the best clinical clues for diagnosis of HIV infection and about which important findings have been published recently. Chronic nonhealing perianal herpes simplex virus (HSV) ulcers are an early clue to HIV infection. With increasing immunodeficiency, recurrences of HSV infection may not heal spontaneously but become persistent and progressive. Untreated, the ulcers may become confluent, forming lesions up to 20 cm in diameter, involving half the face or the circumferential skin around the anus. Cytomegalovirus may coexist in these ulcerations or may produce similar lesions independently.<sup>1</sup>
Syphilis
Authors: G. Marshall Crawford
Journal: New England Journal of Medicine (1948)

Syphilis in Pregnancy One of the most favorable situations for the use of penicillin in syphilis seems to be during pregnancy. The antibiotic appears to be especially effective during the gravid state, having almost a dramatic influence. It should certainly replace arsenotherapy without qualification in pregnancy with syphilis. Practically every report dealing with this phase of syphilis is an unqualified endorsement of the use of penicillin.As in other phases of the disease, numerous schedules have been employed experimentally and the minimum treatment standards are beginning to be established. In general it is agreed that not less than 2,400,000 units . . .
Blood, New York
Journal: JAMA (1969)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
AB0081 Occupation and Risk of Developing Rheumatoid Arthritis
Authors: A. Ilar, L. Alfredsson, P. Wiebert, L. Klareskog, C. Bengtsson
Journal: Annals of the Rheumatic Diseases (2016)

<h3>Background</h3> Due to the proposed etiologic involvement of the lung in the development of rheumatoid arthritis (RA), there is reason to study whether other airborne exposures than smoking and silica dust increase the risk of RA. By finding occupations that are related to RA, we can get a hint of which hazardous agents that may be involved in the disease development. <h3>Objectives</h3> The aim of this study was to estimate the association between occupation and the risk of anti-citrullinated protein antibody positive (ACPA+) or ACPA- RA in men and women. <h3>Methods</h3> The study was based on the Swedish population-based case-control study Epidemiological Investigation of Rheumatoid Arthritis (EIRA), including men and women aged 18–70 years. Controls were matched to cases on sex, age group and residential area. Participants were enrolled between 1996 and 2014. Self-reported data on occupational history, environmental- and lifestyle factors were collected by a questionnaire. Blood samples were taken at clinics to assess the ACPA status of the cases. We used unconditional logistic regression to assess the odds ratios (ORs) and 95% confidence intervals (CIs) of RA due to last occupation before study inclusion among 3,557 cases and 5,665 controls. Occupations were divided into 70 occupational groups and occupations within the professional, technical, administrative, managerial and administrative fields served as the reference group. Crude ORs were adjusted for age group and geographical area, and for the adjusted model we added pack-years of smoking, alcohol use, university degree and BMI. <h3>Results</h3> After adjusting for confounding from pack-years of smoking, alcohol use, university degree and BMI, only assistant nurses and attendants in psychiatric care were associated with a significantly increased risk of ACPA+ RA (OR: 1.3, 95% CI: 1.1–1.5). No occupations among women were significantly related to ACPA- RA after adjustment for the confounders. Among men, electrical and electronics workers (OR: 2.1, 95% CI: 1.1–3.7), bricklayers and concrete workers (OR: 2.9, 95% CI: 1.4–5.7) and material handling operators (OR: 2.1, 95% CI: 1.2–3.9) had an increased risk of ACPA+ RA. Electrical and electronics workers (OR: 2.6, 95% CI: 1.3–5.0) as well as bricklayers and concrete workers (OR: 2.6, 95% CI: 1.1–5.9) also had an increased risk of ACPA- RA. <h3>Conclusions</h3> Several occupations were related to ACPA+ or ACPA- RA. Mainly occupations within the manufacturing field were related to RA, and fewer women than men were working in this field. Adjustment for pack-years of smoking, alcohol use, university degree and BMI could not explain why certain occupations were related to an increased risk of ACPA+ or ACPA- RA, supporting the theory that there is an involvement from other harmful, occupational agents. <h3>Disclosure of Interest</h3> None declared
International Directory of Specialized Cancer Research and Treatment Establishments
Journal: Gut (1977)

This book reports on the papers and discussion at a symposium of which the date and site are unfortunately not men- tioned in the book. (On inquiry, the pub- lishers tell us that it was held at the Welsh National School of Medicine on 7, 8, and 9 July 1975 and that it was a Postgraduate Course in paediatric gastro- enterology organised by J. A. Dodge).It covers development of the gut in the fetus and young children; infancy and its problems; diarrhoea; abdominal pain, and constipation.It conveniently brings together much valuable scattered infor- mation, but the price seems high for a paperback.
Obituary
Authors: Ralph Pemberton, M After
Journal: Annals of the Rheumatic Diseases (1949)

Philadelphia General Hospital he practised in Philadelphia.While at the hospital he was deeply distressed and interested in the plight of the many " rheumatics ", for whom morphia offered the only form of treatment and relief.His practice naturally centred around this interest, and he became known for his writings on the subject.When the World War 1914-18 came, he was assigned, as a Major in the Medical Corps of the United States Army, to the intensive study and treatment of arthritis.He carried on the observations begun in the Presbyterian Hospital in Philadelphia (where he served for eighteen years).The result of these studies stimu- lated increased nation-wide interest.After the war he returned to research as
Massachusetts Medical Society
Authors: Albert O. Seeler
Journal: New England Journal of Medicine (1959)

TOXIC HAZARDS*Talc Pneumoconiosis†Talc is used extensively in industry as a filler and dusting agent. Most of the yearly domestic production of approximately 500,000 tons is consumed by the following industries: ceramics; rubber; paint; paper; roofing; insecticide; and cosmetics. Although talc is the name for a specific mineral, hydrous magnesium silicate (H2Mg3-[SiO3]4), in industry the term talc is applied to various mixtures of a group of minerals including talc, serpentine, dolomite and tremolite that have similar physical properties though they differ in chemical composition. Unfortunately, some commercial talcs contain appreciable quantities . . .
Behcet's disease in a patient with chronic myelogenous leukemia under hydroxyurea treatment: A case report and review of the literature
Authors: George Vaiopoulos, Evangelos Terpos, Nora Viniou, Konstantinos Nodaros, John Rombos, Dimitris Loukopoulos
Journal: American Journal of Hematology (2001)

Behcet's disease (BD) is a chronic, relapsing vasculitis of unknown etiology. Its association with chronic myelogenous leukemia (CML) is extremely rare, and typical manifestations of BD were observed in a very few patients with CML, mainly under interferon-alpha (IFN-α) treatment. Skin pathergy test, being positive in about 50% of patients with BD, is also positive in some IFN-α-treated patients with CML without any evidence of BD symptoms. We describe a 62-year-old woman with CML who developed characteristic features of BD, including a positive skin hyperactivity test, during treatment with hydroxyurea. Hydroxyurea has been implicated in the appearance of skin vasculitic ulceration, but this is the first case, according to our knowledge, where the development of BD was observed during hydroxyurea maintenance in the chronic phase of CML. Am. J. Hematol. 66:57–58, 2001. © 2001 Wiley-Liss, Inc.
Abstract
Authors: Nwabundo Anusim, Bana Antonios, Ruby Gupta, Vishal Jindal, John Khoury, Ishmael Jaiyesimi, Devarshi Bhattacharyya, Jashneel Agraval, Henry Chan, Sabrina Browning, Crawford Lake, Terri Parker, Noffar Bar, Tara Anderson, Stuart Seropian, Andrew Lischuk, Andrew Haims, Natalia Neparidze, Claudio Cerchione, Lucio Catalano, Giovanni Martinelli
Journal: American Journal of Hematology (2020)

Background: EATL is very rare and accounts for less than 1 percent of all non-Hodgkin lymphomas.EATL occurs most commonly in patients with celiac disease and carries a uniformly poor prognosis.The optimal treatment for EATL is unclear and the data is limited to case reports and small retrospective studies.Methods: ICD-O-3 (9717) histological code was used to identify cases of EATL from the population-based cancer registries of the Surveillance Epidemiology and End Results program (SEER) between 2006 and 2016.Frequency, demographics, and survival data were assessed using SPSS statistical software.Results: A total of 138 cases were found.The median age of diagnosis was 66. EATL was more common in men (54.3%) and in Caucasians (76.8%).Of all EATL cases, 53.6% received chemotherapy and only 3.6% received radiation therapy.EATL was the cause of death in 58 % of the cases.Median overall survival (OS) was 3 months; 95% CI, (1.4 to 4.5 months) and disease specific overall survival (DSOS) was 8 months; 95% CI, (3.8 to 12.1 months).Chemotherapy significantly improved both OS (7 months vs 1 month; P< 0.001) and DSOS (12 months vs 6 months; P=0.005).Multivariable analysis demonstrated that age, sex, race and radiation therapy were not associated with mortality.Chemotherapy was associated with decreased mortality risk (HR, 0.48; CI, 0.32 -0.71; p< 0.001) Conclusions: EATL is a rare subtype of non-Hodgkin lymphoma.Despite the advances in treating non-Hodgkin lymphomas, EATL prognosis remains poor.In concordance with previously reported data, chemotherapy has shown to mitigate the poor prognosis associated with EATL in our study.
Entstehung, Erkennung und Behandlung innerer Krankheiten.
Journal: JAMA (1931)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Immunization by selective infection with type 4 adenovirus grown in human diploid tissue culture. II. specific protective effect against epidemic disease
Authors: W. P. Edmondson
Journal: JAMA (1966)

In a previous study (see pp 445-452) the response of adult volunteers to type 4 adenovirus administered in an enteric-coated capsule was evaluated. Infection produced in this manner was limited to the lower intestinal tract and was not associated with any signs or symptoms of illness. Selective intestinal infection with type 4 virus produced moderate levels of neutralizing antibody. In addition, infection did not spread to susceptible contacts despite their prolonged exposure to individuals who shed virus from the intestinal tract. The virus preparation which was studied most extensively was grown in human diploid fibroblast culture (WI 38) and was found to be free of adventitious microbial agents and of oncogenic activity in suckling hamsters. The total experience from the laboratory studies and from the response of the volunteers to enteric infection suggested that administration of type 4 adenovirus in an entericcoated capsule might provide a safe and effective means
Alcohol-acetaminophen issue explored
Journal: JAMA (1980)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Saving lives?
Authors: E. B. Winslow
Journal: JAMA (1979)

Cardiopulmonary resuscitation (CPR) has become a fairly common medical procedure. Many patients who die in hospitals have had CPR administered to them. Most of these patients have advanced disease and their cardiac arrest is not unexpected. In this setting attempts at resuscitation usually do little to change the outcome. In the hospital but out of the intensive care unit, the success rate of CPR (as measured by discharge from the hospital) is about 10%. However, the results of resuscitation from out-of-hospital ventricular fibrillation due to atherosclerotic heart disease are better. If resuscitation is begun early, before brain damage occurs (within four to six minutes of cessation of blood flow), 30% to 45% of patients can return to their prearrest state.<sup>1,2</sup> Considering the potential for patient salvage, who should initiate out-of-hospital CPR, and how should they be trained? As recently as 1967 it was thought that only physicians should be
OSHA's Approach to Risk Assessment for Setting a Revised Occupational Exposure Standard for 1,3-Butadiene
Authors: Elizabeth A. Grossman, John Martonik
Journal: Environmental Health Perspectives (1990)

In its 1980 benzene decision [Industrial Union Department, ALF-CIO v. American Petroleum Institute, 448 U.S. 607 (1980)], the Supreme Court ruled that "before he can promulgate any permanent health or safety standard, the Secretary [of Labor] is required to make a threshold finding that a place of employment is unsafe--in the sense that significant risks are present and can be lessened by a change in practices" (448 U.S. at 642). The Occupational Safety and Health Administration (OSHA) has interpreted this to mean that whenever possible, it must quantify the risk associated with occupational exposure to a toxic substance at the current permissible exposure limit (PEL). If OSHA determines that there is significant risk to workers' health at its current standard, then it must quantify the risk associated with a variety of alternative standards to determine at what level, if any, occupational exposure to a substance no longer poses a significant risk. For rulemaking on occupational exposure to 1,3-butadiene, there are two studies that are suitable for quantitative risk assessment. One is a mouse inhalation bioassay conducted by the National Toxicology Program (NTP), and the other is a rat inhalation bioassay conducted by Hazelton Laboratories Europe. Of the four risk assessments that have been submitted to OSHA, all four have used the mouse and/or rat data with a variety of models to quantify the risk associated with occupational exposure to 1,3-butadiene. In addition, OSHA has performed its own risk assessment using the female mouse and female rat data and the one-hit and multistage models.(ABSTRACT TRUNCATED AT 250 WORDS)
Society Proceedings
Journal: JAMA (1930)

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Exercise and Food for Pulmonary Invalids.
Journal: JAMA (1895)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal