tbuckley/cabot-search huggingface dataset:
NURSING AND PATRIOTISM.
Journal: JAMA (2004)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Physician computer network: ad gimmick or efficiency tool?
Authors: R. N. Fahmy
Journal: JAMA (1991)

<h3>To the Editor.</h3> —I have been asked to sign up for a program that promises to save the clinic $11 000 annually and provide $30 000 worth of state-of-the-art computer equipment. The organization is called the Physician Computer Network (PCN); it aims to enroll 45 000 physicians. The literature on this product is found in publications not routinely read by physicians.<sup>1-3</sup>The PCN has interest in medical education, clinical information, and marketing research. It has received "educational" grants from 10 major pharmaceutical manufacturers. Considering the magnitude of this new campaign, physicians should consider the ethics of participating in such a program. The PCN provides extensive hardware and software computer equipment free of charge. The system has numerous capabilities including linkage to local hospitals for convenient access to patient information. There is an annual membership fee. Each participant is required to review up to 32 product advertisements, 10 product mail
British Journal of Obstetrics and Gynaecology
Journal: BMJ (1975)

The circadian secretory profiles of serum prolactin, growth hormone and cortisol were measured in two women suffering from severe premenstrual tension syndrome and in two asymptomatic control subjects.Subjects and controls were screened and included after a rigorous selection process.Blood samples were obtained every 30 min over a period of 24 h in each woman both on day 9 (follicular phase) and day 26 (luteal phase) of the menstrual cycle.There was no relationship between the hormonal secretory profiles and the premenstrual tension syndrome.
Contents
Authors: Ann Sofia, S Thomsen, Yousif Subhi, Jens Folke Kiilgaard, La Cour, Lars Konge, Alberto Diniz-Filho, Erwin Boer, Carolina Gracitelli, Ricardo Abe, Nienke Van Driel, Zhiyong Yang, Felipe Medeiros, Martina Suzani, Anthony Moore, Thomas Cuilla, Gui-Shuang Ying, Maureen Maguire, Daniel Martin, Glenn Jaffe, Juan Grunwald, Ebenezer Daniel, Cynthia Toth, Jolanda De Groot-Mijnes, Jojanneke Dekkers, Lenneke De Visser, Aniki Rothova, Anton Van Loon, Joke De Boer, Akihito Uji, Nagahisa Yoshimura
Journal: Ophthalmology (2015)
Dietary Supplements of Linolenic Acid May Help Avert Coronary Thrombosis
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines
Authors: Paul K. Whelton, Robert M. Carey, Wilbert S. Aronow, Donald E. Casey, Karen J. Collins, Cheryl Dennison Himmelfarb, Sondra M. DePalma, Samuel Gidding, Kenneth A. Jamerson, Daniel W. Jones, Eric J. MacLaughlin, Paul Muntner, Bruce Ovbiagele, Sidney C. Smith, Crystal C. Spencer, Randall S. Stafford, Sandra J. Taler, Randal J. Thomas, Kim A. Williams, Jeff D. Williamson, Jackson T. Wright
Journal: Circulation (2018)
The Metropolitan Acid Aerosol Characterization Study: Results from the Summer 1994 Washington, D.C. Field Study
Authors: Helen H. Suh, Yurika Nishioka, George A. Allen, Petros Koutrakis, Robert M. Burton
Journal: Environmental Health Perspectives (1997)

An ambient particle monitoring study was conducted in Washington, D.C. during the summer of 1994 as part of the Metropolitan Acid Aerosol Characterization Study (MAACS). Acid aerosol and inhalable (particulate matter with aerodynamic diameters < 10 micron; PM10) and fine (particulate matter with aerodynamic diameters < 2.5 micron; PM2.5) particle samples were collected for 24-hr periods (9 A.M.-9 A.M. EDT) on alternate days at six monitoring sites located throughout the greater Washington, D.C. area. Monitoring sites were located in both urban and rural areas and were generally situated along a southwest to northeast line due to the prevailing winds. Information on site characteristics, including population density and distance from the city center, was also obtained, as were data on meteorological parameters. Results from this study show strong correlations among the particulate measures, PM10, PM2.5, SO4(2-), and H+. These strong correlations resulted from the fact that PM2.5 comprised 77% of PM10, with SO4(2-)-related species accounting for 49% of total PM2.5. PM10, PM2.5, SO4(2-), and H+ concentrations were found to be uniform across the metropolitan Washington area. Spatial variation was found, however, for coarse particles (PM2.5-10) and NH3 concentrations. In our previous Philadelphia study, population density was an important determinant of spatial variation in coarse particles and NH3 concentrations, however, in Washington, D.C., population density was not associated with observed spatial patterns in coarse particle concentrations, but was an important determinant of NH3 concentrations. When data from one site (Reservoir) was excluded from the analysis, population density explained larger percentage of the variability in NH3 levels and became an important determinant of the H+/SO4(2-) ratio as well. Ambient H+ models developed from Philadelphia data were found to predict H+ concentrations in Washington, D.C. reasonably well, representing an improvement over measurements made at a single stationary ambient monitoring site.
Infantile acne.
Authors: D Rowley-Jones
Journal: BMJ (1977)

SIV infection of sooty mangabeys (SMs), a natural host species, does not cause AIDS despite high-level virus replication. In contrast, SIV infection of nonnatural hosts such as rhesus macaques (RMs) induces an AIDS-like disease. The depletion of CD8<sup>+</sup> T cells during SIV infection of RMs results in marked increases in plasma viremia, suggesting a key role for CD8<sup>+</sup> T cells in controlling levels of SIV replication. To assess the role that CD8<sup>+</sup> T cells play in determining the virologic and immunologic features of nonpathogenic SIV infection in SMs, we transiently depleted CD8<sup>+</sup> T cells in SIV-infected and uninfected SMs using a CD8α-specific Ab (OKT8F) previously used in studies of SIV-infected RMs. Treatment of SMs with the OKT8F Ab resulted in the prompt and profound depletion of CD8<sup>+</sup> T cells. However, in contrast to CD8<sup>+</sup> cell depleted, SIV-infected RMs, only minor changes in the levels of plasma viremia were observed in most SIV-infected SMs during the period of CD8<sup>+</sup> cell deficiency. Those SMs demonstrating greater increases in SIV replication following CD8<sup>+</sup> cell depletion also displayed higher levels of CD4<sup>+</sup> T cell activation and/or evidence of CMV reactivation, suggesting that an expanded target cell pool rather than the absence of CD8<sup>+</sup> T cell control may have been primarily responsible for transient increases in viremia. These data indicate that CD8<sup>+</sup> T cells exert a limited influence in determining the levels of SIV replication in SMs and provide additional evidence demonstrating that the absence of AIDS in SIV-infected SMs is not due to the effective control of viral replication by cellular immune responses.
Announcements
Authors: Shiv Sarin, David Semela, Stuart Forbes, Tania Roskams, Frederik Nevens, Fabio Marra, Arun Sanyal, Jacob George, Massimo Pinzani, Norifumi Kawada, Matt Wright, Klaas Poelstra, Daniel Dhumeaux, Yogesh Chawla, Jean-Michel Pawlotsky, Laurentius Leismana, Antonio Bertoletti, Scott Friedman, Nancy Leung, Hong Kong, Gamal Shiha, Alaa-Eldin Ibrahim
Journal: Journal of Hepatology (2007)
On the biological role of cyclic AMP
Authors: E. W. Sutherland
Journal: JAMA (1970)

Before discussing the role of cyclicadenylate, or adenosine 3′,5′-monophosphate (cyclic AMP) in biology, I would like to make a few brief remarks about another subject, the role of the basic scientist in medicine. I would like to hope that this and the subject that I have been asked to write about are not completely unrelated. I bring this other subject up for two main reasons. First, I am myself optimistic about what the scientist can offer to the world, and especially to medicine. But second, I find others, ranging from beginning medical students to high government officials, who are not so optimistic. I am not overly concerned about our medical students, for the young have always been short on historical perspective and long on idealism. They sense, quite rightly in my view, that American medicine has fallen short of its earlier promise, and they are impatient to do something about
Bacterial contamination of arterial lines. A prospective study
Authors: T. Shinozaki
Journal: JAMA (1983)

One hundred seventeen patients had indwelling arterial lines for hemodynamic monitoring and blood sampling. The duration of catheterization varied from 25 to 439 hours, during which time no components of the system were replaced. In contrast to other reports, our study showed no instance of contamination of transducer dome fluid when the continuous flush device was located just distal to the transducer. The sampling stopcock showed bacterial growth in 16.2% of patients. In the one case in which the arterial catheter tip, stopcock, and patient's blood showed the same organism, culture of the transducer fluid was negative. Our results suggest that elimination of a static inline fluid column and proper aseptic sampling technique limit risk to the patient of transmitted bacterial infection from the fluid in the system. Routine changes of components of the system are not indicated and a substantial cost saving can be achieved. (<i>JAMA</i>1983;249:223-225)
Immunological and Trophic Functions of Lymphocytes
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
REMOVAL OF THE OVARIES AS A THERAPEUTIC MEASURE IN PUBLIC INSTITUTIONS FOR THE INSANE.
Journal: JAMA (1893)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Lasker medical research awards a 35-year tradition
Authors: R. S. Johnson
Journal: JAMA (1981)

The 1980 Albert Lasker Medical Research Awards were presented toward the end of the year to nine scientists and to the National Heart, Lung, and Blood Institute, one of the National Institutes of Health in Bethesda, Md. Four US scientists from California shared the $15,000 Basic Medical Research Award for their work that led to the development of the field of recombinant DNA research. They are Paul Berg, PhD (also a 1980 Nobel Laureate), A. Dale Kaiser, PhD, and Stanley N. Cohen, MD, all of Stanford University School of Medicine, and Herbert W. Boyer, PhD, of the University of California, San Francisco. The $15,000 Clinical Medical Research Award was won by a US team of three and an English team of two scientists for their independent development of a vaccine for preventing Rh disease in newborn infants. Vincent J. Freda, MD, and John G. Gorman, MD, both of Columbia University
Correction
Journal: BMJ (1945)

A surgeon who is well known to me was able to prepare for and make one serious attempt at passing the Final F.R.C.S. examination.He failed in one of the six parts.From then onwards he took passing shots at the examination each time it came round, but without further preparation.Each time for five times he failed in one of the six parts, and each time it was in a different part, so that in all six attempts he failed
GH Response to Oral Glucose Tolerance Test: A Comparison between Patients with Acromegaly and Other Pituitary Disorders
Authors: E. Verrua, M. Filopanti, C. L. Ronchi, L. Olgiati, E. Ferrante, C. Giavoli, E. Sala, G. Mantovani, M. Arosio, P. Beck-Peccoz, A. G. Lania, A. Spada
Journal: Endocrine Reviews (2010)

Context The cutoff value of nadir GH after an oral glucose tolerance test (OGTT) used to define disease remission in acromegaly is higher than that observed in healthy subjects. However, it is uncertain whether the impaired GH inhibition might be related to subtle abnormalities of GH secretion or to functional and/or anatomical hypothalamic-pituitary disconnection due to tumor per se or treatments. Objective The objective of the study was to evaluate the impact of pituitary disorders other than acromegaly on GH response to OGTT. Design, Subjects, and Methods Thirty-three patients (24 females and nine males, aged 50.1 ± 12.3 yr, 13 operated and two irradiated) with various hypothalamic-pituitary disorders (HPDs), 45 healthy subjects (controls), and 42 cured acromegalic patients matched for sex, age. and body mass index were investigated. All subjects were studied for IGF-I levels and GH levels before and during the OGTT. Results In HPD patients mean postglucose nadir GH levels were 0.11 ± 0.08 μg/liter without any difference between patients treated with neurosurgery and/or radiotherapy and untreated and between patients with and without pituitary stalk alterations and/or hyperprolactinemia. Mean nadir GH values were similar in HPD patients and controls (0.11 ± 0.08 vs. 0.08 ± 0.08 μg/liter, P = 0.23) and lower than those found in cured acromegalic patients (0.18 ± 0.13 μg/liter, P = 0.02), although there was an overlapping in about half of patients. Conclusions Hypothalamic control of glucose-mediated GH suppression is not perturbed in patients with HPD. These data indicate that defective GH suppression to glucose that is found in acromegaly is unlikely to reflect a lack of integrity of hypothalamic function.
Metabolism of Trichloroethylene and Tetrachloroethylene in Human Subjects
Authors: Masayuki Ikeda
Journal: Environmental Health Perspectives (1977)

A linear correlation exists between the trichloroethylene concentration in the work environments and the level of total trichloro compounds in the urine of the workers, as expressed by the equation: Gamma = 7.25=chi + 5.5, where Gamma is trichloroethylene in air (ppm) is Chi is total trichloro compounds in urine (mg/l). Trichloroethanol level is also linearly related to trichloroethylene concentration, while trichloroacetic acid level deviates from the linear relation when trichloroethylene level exceeds 50 ppm. In the case of tetrachloroethylene exposure, both trichloroethanol and trichloroacetic acid levels, and consequently the total trichloro compound level, reach a plateau at tetrachloroethylene level well below 100 ppm. The mean urinary biological half-life is 41 hr for trichloroethylene and 144 hr for tetrachloroethylene. The two values are the largest of the values so far obtained with organic solvents. The respiratory half-life is shorter than the urinary half-life, both in richloroethylene and in tetrachloroethylene. Applications of the urinalyses in clinical cases are described. In one case of trichlorethylene dependency, a longer urinary half-life of 73 hr was observed. An automated system is presented for the determination of total trichloro compounds in human urine. The system can analyze the samples at the rate of 20 samples per hour with an accuracy comparable to that of the time-consuming manual analysis.
Late Post-traumatic Headache
Journal: BMJ (1966)

Sections 5 8 and 59 of the Act are con- veniently quoted by Mrs. Jenkins.'The word " unlawfully " occurs six times, and became the main issue in R. v. Bourne, 1938, which established that abortion can be lawful and unlawful, only the latter being felonious.3That the Act is capable of being misinterpreted by jurists of the eminence of Rupert Cross (in a broadcast talk) is sufficient reason for restating the law, but only increases the need to restate the law accurately.A myth has been created that every time a surgeon performs an abortion the police turn a blind eye, much as they are expected to if he has left his car in the wrong place during the operation.It ought to be under- stood, once and for all, that abortion is an operation like any other operation: the law can neither compel a surgeon to perform it nor, provided his position is ethical, punish him for performing it.What needs changing is not the law but the myth.-Iam, etc.,
Therapeutic nonequivalence of oxytetracycline capsules
Authors: G. W. Brice
Journal: JAMA (1969)

<h3>To the Editor:—</h3> For some time, it has been evident that factors other than those customarily examined enter into the therapeutic usefulness of many drugs. Varley<sup>1</sup>has shown that two chemically equivalent preparations of tolbutamide can differ very significantly in availability to the patient and efficacy of the drug, although both meet official specifications. There are other reports<sup>2,3</sup>on the effect of pharmaceutical factors on drug availability, and Friend<sup>4</sup>points to the necessity of "making sure by measuring patients' blood levels or by adequate therapeutic testing that a drug preparation varying in any way from one performing satisfactorily is also capable of doing what is claimed for it." We have conducted a series of serum level studies on 16 lots of oxytetracycline capsules, labelled 250 mg potency, and distributed by 13 different suppliers. Each of these lots was certified by the Food and Drug Administration and our
The Cover
Authors: Owen Findsen
Journal: JAMA (1986)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal