tbuckley/cabot-search huggingface dataset:
Dermatitis Herpetiformis and Celiac Disease
Authors: A. Vishnu Moorthy, Stephen W. Zimmerman, Peter E. Maxim
Journal: JAMA (1978)

DERMATITIS herpetiformis is a disease of unknown cause, which is characterized by recurrent bullous eruptions of the skin often associated with gluten-sensitive enteropathy (celiac disease). Cutaneous deposition of IgA, the presence of circulating immune complexes, and an increased incidence of histocompatibility antigen HLA-B8 as well as an association with immunologic disorders, eg, thyroid disease, rheumatoid arthritis, chronic liver disease, cutaneous vasculitis, Addison's disease, systemic lupus erythematosus (SLE), and ulcerative colitis, have led to the speculation of immunologic alterations in dermatitis herpetiformis.<sup>1</sup>Glomerular deposition of immune complexes is a major pathogenic mechanism of mediation of injury in patients with glomerulonephritis.<sup>2</sup> <h3>Materials and Methods</h3> Biopsy material was processed as previously described.<sup>3</sup>Briefly, tissue for light microscopic examination was fixed in buffered 4% formaldehyde solution (10% formalin) embedded in paraffin sectioned at 2 μ, and stained with hematoxylin
The AMA and the armed forces medical services
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Streptococcus Antibody
Journal: JAMA (1977)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
<i>Notice to Readers</i>: Online Manuscript Submission System Now Available for <i>MMWR</i> Serial Publications
Journal: MMWR Morbidity and Mortality Weekly Report (2018)

The MMWR Serial Publications are now using ScholarOne Manuscripts, an online system for manuscript submissions. This system provides comprehensive workflow management and streamlines the submission process for Recommendations and Reports, Surveillance Summaries, and Supplements.
Septic Shock
Authors: John Richardson, T Ahern, Drs Newnham, R St, G Buxton, Liliane Clopet, Major- Gencral Rogers, A Keatinge, S Bower, J Milne, D Picken, C Mann, T Esson, A Mackay, H Sparrow, H Williamson, J Jones, T Oliver, P Raffle, J Sutherland, F Wigglesworth, J Hughes, L Davidson, I Mcphail, J Seddon, M Benson, D Ballantyne, C Morkane, W Ander- Son, Mr Murray, Weston As, Drs Ward, J Roopchand, V Massiah, T Holme, A Qunta, C Elliott, J Galletly, A Torrance, R Midha, L Morgan, G Moses, D Rowlands, Mr Wilson, Menna Price
Journal: BMJ (1970)
Performance of CCP assay in an updated series of biopsy samples obtained from commercial testing.
Authors: John W. Davis, E. David Crawford, Neal Shore, Peter T. Scardino, Jonathan D. Tward, Lowndes Harrison, Brent Evans, Lisa FitzGerald, Steven Stone, Michael K. Brawer
Journal: Journal of Clinical Oncology (2015)

5033 Background: The cell cycle progression (CCP) score is an RNA−based expression assay, which has improved the prediction of prostate cancer aggressiveness in nine separate retrospective cohorts. In this analysis, we characterized the patient population and CCP score performance in commercial testing. Methods: Formalin−fixed prostate biopsy samples from 4261 patients were submitted by 930 physicians to Myriad Genetic Laboratories for CCP test analysis. Patient clinicopathologic data was obtained from the test request form. The CCP score was calculated based on RNA expression of 31 cell cycle progression genes normalized to 15 housekeeping genes. Patients were sorted in to AUA risk categories and assigned a relative classification of cancer aggressiveness based on the CCP score. Results: Of the 4261 samples that contained sufficient carcinoma ( > 0.5mm linear extent), 4218 (99.0%) provided quality RNA for analysis. The CCP score distribution ranged from −2.9 to 3.4. Correlation with Gleason score was r = 0.35 and the correlation with PSA was r = 0.16. Based on the CCP score, 36.8% of men had a less aggressive cancer and 21.2% of patients had a more aggressive cancer than expected based on clinicopathologic prediction. Conclusions: The CCP test can improve risk stratification for men with prostate adenocarcinoma independent of other clinicopathologic variables. Fifty−eight percent of men tested in the commercial assay were assigned to a different risk category than predicted by their clinicopathologic features.
Circumcision
Authors: Herbert Freilich
Journal: JAMA (1982)

<h3>To the Editor.—</h3> I am writing to object to a statement in the QUESTIONS AND ANSWERS section by Dr Kempe entitled "Neonatal Ear Piercing" (1982; 247:3261). Dr Kempe's reply is a subtle demonstration of how personal bias can influence a physician's thinking. For a man of his stature, I hope it was unintentional. In response to a simple question whether piercing the ear of a neonate constitutes child abuse, Dr Kempe suddenly and without logic brings up the subject of circumcision. He equates the two as both being of no value, with ear piercing as more favorable, since it causes less pain. For his edification, I would like to point out that circumcision is a fundamental religious belief and practice of two of the world's great religions— Judaism and Mohammedanism. Its origin is directly described in the<i>Bible</i>, which is sacred to three religions, when Abraham circumcised his son Isaac.
Relationship of Acute Bronchiolitis to Bronchial Asthma: Four to Fourteen Year Follow-Up
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Detection of Australia antigen in various fractions of frozen blood
Authors: J. Werch
Journal: JAMA (1971)

Viral hepatitis has not been reported following transfusion with frozen blood. Seven such samples from donors positive for Australia (Au/SH) antigen were studied. After thawing, Au/SH antigen was found in five of seven discarded wash solutions and in only one of the seven supernatant reconstituting saline solutions which form part of the transfused product. The positive sample came from a patient who had the highest titer of Au/SH antigen in his serum. The freeze-thaw processing appears to dilute out serum hepatitis and the associated Au/SH antigen, so that overt hepatitis does not follow administration of frozen blood.
Brace Placement Incorrect
Journal: JAMA (1976)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Urease Test of Isoniazid-Resistant Human Tubercle Bacilli
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
From the Authors
Authors: V. Gracchi, M. Boel, J. Van der Laag, C.K. Van der Ent
Journal: European Respiratory Journal (2004)

reproducibility of between 6-10% in most cases; and 3) small numbers in some subgroups meant that an 8.3% difference in "success rate" equates to a difference in performance of a single child.In conclusion, while we agree that when using the protocol described in this study there is minimal evidence of improved reproducibility, we believe that there is a role in the younger age group for these computer animation incentive programs provided they are used to their full capabilities.We therefore suggest that, before the use of such incentives is dismissed out of hand, further work should be undertaken to clarify these issues, having first ascertained appropriate quality control criteria for spirometry in very young children.
Study of bisphosphonates leads to new views of bone remodeling, therapy for skeletal malignancy
Authors: C. Marwick
Journal: JAMA (1997)

CHEMICAL compounds called bisphosphonates, some of which were originally used as water softeners, are playing an increasing role in the treatment of metastatic skeletal malignancies. The development may provide new insights into the normal processes involved in bone remodeling. Some solid tumors, especially those of the breast, prostate, and lung, readily metastasize to bone, where they stimulate its formation or, more frequently, its destruction. Since bisphosphonates inhibit bone turnover by decreasing bone resorption, investigators have become interested in studying their possible use for controlling or even preventing metastatic skeletal lesions. "We've been remiss in not considering this specific problem of bone metastasis. We need to understand it to develop rational ways of preventing and treating it. The information is now available or is on the horizon which can really make a difference in this process," said Gregory Mundy, MD, introducing a symposium last month at the National Institutes of Health
SALINE INFUSIONS.
Journal: JAMA (1898)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Colorectal cancer risk prediction tool for men and women without known susceptibility
Authors: A. N. Freedman, M. L. Slattery, R. Ballard-Barbash, G. Willis, B. J. Cann, D. Pee, M. H. Gail, R. M. Pfeiffer
Journal: Journal of Clinical Oncology (2009)

e15002 Background: Given the high incidence of colorectal cancer (CRC), and the availability of procedures that can detect disease and remove precancerous lesions, there is a need for a model that estimates the probability of developing CRC across various age intervals and risk factor profiles. Methods: The development of separate CRC absolute risk models for men and women included estimating relative risks and attributable risk parameters from population-based case-control data separately for proximal, distal, and rectal cancer and combining these estimates with baseline age-specific cancer hazard rates based on Surveillance, Epidemiology, and End Results (SEER) incidence rates and competing mortality risks. Results: For men, the model included a cancer- negative sigmoidoscopy/colonoscopy in the last 10 years, polyp history in the last 10 years, history of CRC in first-degree relatives, aspirin and nonsteroidal anti-inflammatory drug (NSAID) use, cigarette smoking, body mass index (BMI), current leisure-time vigorous activity, and vegetable consumption. For women, the model included sigmoidoscopy/colonoscopy, polyp history, history of CRC in first-degree relatives, aspirin and NSAID use, BMI, leisure-time vigorous activity, vegetable consumption, hormone-replacement therapy (HRT), and estrogen exposure on the basis of menopausal status. For men and women, relative risks differed slightly by tumor site. A validation study in independent data indicates that the models for men and women are well calibrated. Conclusions: We developed absolute risk prediction models for CRC from population-based data, and a simple questionnaire suitable for self-administration. This model is potentially useful for counseling, for designing research intervention studies, and for other applications. No significant financial relationships to disclose.
Pediatric Neurology
Authors: Gerald F. Tremblay
Journal: JAMA (2006)

Inspecting my shelves one day about 25 years ago, a wide-eyed friend asked me why medical books are so big. I don't recall my answer, but I hoped he thought those big books meant I knew a lot of medicine. I didn't then and don't now, of course, and that's why I need the big books.
A multistate outbreak of Salmonella javiana and Salmonella oranienburg infections due to consumption of contaminated cheese
Authors: C. W. Hedberg
Journal: JAMA (1992)

<h3>Objective.</h3> —To determine the source of an outbreak of<i>Salmonella javiana</i>and<i>Salmonella oranienburg</i>infections. <h3>Design.</h3> —Laboratory-based statewide surveillance for<i>Salmonella</i>infections and two separate case-control studies. <h3>Setting.</h3> —Community- and industry-based studies conducted from May through October 1989. <h3>Participants.</h3> —Thiry-one culture-confirmed outbreak-associated cases of<i>S javiana</i>infection and 60 community controls matched for telephone prefix, gender, and age in case-control study I; 50 cases, 100 community controls, and 64 family member controls in case-control study II. <h3>Results.</h3> —One hundred thirty-six culture-confirmed cases of<i>S javiana</i>infection and 11 cases of<i>S oranienburg</i>infection were associated with the outbreak in Minnesota. Outbreak-associated cases were also identified in Wisconsin (15 cases), and in Michigan and New York (one case each). Cases were more likely than controls to have consumed mozzarella cheese manufactured at a single cheese plant (plant X) or cheese that had been shredded at processing plants that also shredded cheese manufactured at plant X (odds ratio [OR], 7.2; 95% confidence interval [Cl], 1.7 to 23.2;<i>P</i>&lt;.01). The outbreak-associated strains of both serovars were isolated from two unopened 16-oz (0.45-kg) blocks of mozzarella cheese produced at plant X. The most probable numbers of<i>Salmonella</i>organisms in these samples were 0.36/100 g and 4.3/100 g. <h3>Conclusions.</h3> —The potential for bacterial pathogen contamination of cheese during manufacture and processing has important epidemiologic implications, particularly because cheese consumption has recently increased in the United States. Low-level contamination of a nationally distributed food product can cause geographically dispersed foodborne outbreaks that may be difficult to detect. (<i>JAMA</i>. 1992;268:3203-3207)
A Treatise on Unripe Cataract.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
INTRACELLULAR TOXINS AND THEIR RELATION TO IMMUNITY.
Journal: JAMA (1903)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
1. Improving Care and Promoting Health in Populations: <i>Standards of Medical Care in Diabetes</i>—<i>2020</i>
Authors: American Diabetes Association
Journal: Diabetes Care (2019)

The American Diabetes Association (ADA) “Standards of Medical Care in Diabetes” includes the ADA’s current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, a multidisciplinary expert committee (https://doi.org/10.2337/dc20-SPPC), are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA’s clinical practice recommendations, please refer to the Standards of Care Introduction (https://doi.org/10.2337/dc20-SINT). Readers who wish to comment on the Standards of Care are invited to do so at professional.diabetes.org/SOC.