tbuckley/cabot-search huggingface dataset:
Brains
Authors: THOMAS BERESFORD
Journal: Annals of Internal Medicine (1981)

Ad Libitum1 February 1981BrainsTHOMAS BERESFORD, M.D.THOMAS BERESFORD, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-94-2-273 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptJohnson, the neurosurgeon, looked more upset than I had ever seen him. He sat at a table in the hospital cafeteria, smoking. An empty cigarette pack was folded in half and jammed into an ashtray along with several butts smoked down to the filters. It was 10:30 in the morning. He wore his surgical greens. His right shoe, blood stained and with electric-conductor soles, tapped nervously against a table leg.Neurosurgeons live a hard life, I thought. I stood in line with my tray, doughnut and coffee. A squadron of nurses from the medical floors was ahead of me. No... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Milwaukee, Wisconsin PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 February 1981Volume 94, Issue 2Page: 273-274KeywordsBloodBrainCoffeeNeurosurgery ePublished: 1 December 2008 Issue Published: 1 February 1981 PDF downloadLoading ...
Society Proceedings
Journal: JAMA (1934)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Meteorological Effects of Environmental Controls
Authors: G. D. Robinson
Journal: Environmental Health Perspectives (1975)

The solution of the continuity equation in practical applications is examined, and the values needed for approximate solutions are indicated. Models are adequate for investigating what could happen, but are less satisfactory for predicting what will happen. An example is given in relation to the distribution of SO2 over Connecticut. More knowledge is needed about atmospheric chemistry before better predictions can be expected. The effect of particulates on atmospheric opacity is reviewed.
Effect of short-term ethanol treatment on voltage-dependent calcium channels in Kupffer cells
Authors: T Hijioka
Journal: Hepatology (1993)

Kupffer cells, the resident hepatic macrophages, are activated by calcium, and several reports indicate that their function (e.g., phagocytosis and cytokine production) is altered by ethanol. We recently found that Kupffer cells contain L-type voltage-dependent Ca2+ channels. The purpose of this study, therefore, was to evaluate the effect of short-term ethanol treatment on voltage-dependent Ca2+ channels in Kupffer cells. Kupffer cells were isolated from rats 2 hr after intragastric administration of ethanol (5 gm/kg intragastrically). Cytosolic free calcium concentration of cultured Kupffer cells was measured with the fluorescent Ca2+ indicator fura-2. In Kupffer cells isolated from control rats, partial replacement of extracellular Na+ by K+ caused an increase in cytosolic free calcium concentration in a concentration-dependent manner (halfmaximal effect was observed with 81 mmol/L K+), presumably because of membrane depolarization. Acute ethanol treatment in vivo shifted the concentration-response curve for K+ to the right (half-maximal effect was observed with 94 mmol/L K+) and reduced the maximal elevation of cytosolic free calcium concentration by means of K+. Significantly, the dihydropyridine-type calcium channel agonist BAY K 8644 (1 μmol/L) shifted the concentration-response curve for K+ to the left in control and ethanol-treated groups (half-maximal effect was observed with 61 and 77 mmol/L K+, respectively). Moreover, the dihydropyridine-type calcium channel blocker nitrendipine (10 μmol/L) prevented the increase in cytosolic free calcium concentration in both groups. When extracellular Ca2+ was omitted from the incubation medium, the increases in cytosolic free calcium concentration due to depolarization were prevented completely. However, direct addition of ethanol to the cell cultures was without effect. Thus these data indicate that short-term ethanol treatment in vivo reduces the probability that L-type voltage-dependent Ca2+ channels in Kupffer cells would be open. This phenomenon could be involved in the mechanism of the effect of ethanol on phagocytosis and cytokine production by Kupffer cells. (HEPATOLOGY 1993;18:400–405).
Human Monstrosities.
Journal: JAMA (1893)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Treatment of Kidney Diseases and High Blood Pressure. Part I. Practical Manual for Physicians and Patients.
Journal: JAMA (1926)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Human immunodeficiency virus test evaluation, performance, and use. Proposals to make good tests better
Authors: J. S. Schwartz
Journal: JAMA (1988)

Human immunodeficiency virus (HIV) tests are essential for detecting asymptomatic infection and are helpful in confirming the diagnoses of acquired immunodeficiency syndrome—related complex and acquired immunodeficiency syndrome. Nonetheless, many aspects of their use remain controversial, partly because of concerns about test accuracy. This article reviews the scientific basis for the evaluation, performance, and use of the most commonly employed HIV assays. Current test performance could be improved by better standardization of test procedures and institution of mandatory proficiency testing and licensure of clinical laboratories that perform HIV testing. Test utility could be enhanced by sequencing tests more appropriately and by interpreting test results in conjunction with the clinical purpose for which the test is being used and the characteristics of the population under study. Finally, HIV tests should be evaluated in a manner that minimizes spectrum and referral bias and inadequate reference standard confirmation, problems that have affected the evaluation of current tests. (<i>JAMA</i>1988;259:2574-2579)
Cholera Vaccination
Authors: M. J. Friedrich
Journal: JAMA (2011)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Artificial Respiration
Authors: W. J. B. Selkirk
Journal: BMJ (1943)

The most common method of normalizing sEMG signals from a given muscle is to refer it to the signal recorded from the same muscle during a maximal voluntary isometric contraction (MVIC). It is still not fully clear, however, what test should be used to produce maximum neural activation in a given muscle, particularly for sEMG analysis of respiratory muscles. The aim of this study was to evaluate and compare RMS values of sEMG of the sternocleidomastoid (SCM), scalene (SCA), diaphragm (eighth intercostal space, EIS) and rectus abdominal (RA), while performing different maneuvers. 24 healthy subjects underwent the protocol (9M, 15F, age 27,8±7,1 years, BMI 23,7±3,4 kg/m², FVC% 92,20 ± 12,63; FEV<sub>1</sub>/FVC% 86,56 ± 4,94). After skin preparation , sEMG signals were acquired by wireless sEMG sensors positioned accordingly to previously published protocols (Falla, 2002; De Andrade, 2005; Maarsingh, 2000), during sniff test, MIP, MEP and MVIC of RA, SCM and SCA. Electromyographic values of the maneuvers and respective signal muscle groups are presented on table 1. In conclusion, MVIC specific for the muscles provides the maximal RMS for SCM, SC and RA muscles, while for the EIS the maneuver providing maximal RMS is MVIC of RA.
<i>QuickStats</i>: Average Number of Deaths from Motor Vehicle Injuries, Suicide, and Homicide,* by Day of the Week — National Vital Statistics System, United States, 2015
Journal: MMWR Morbidity and Mortality Weekly Report (2017)

In 2015, an average of 103 motor vehicle injury deaths, 121 suicides, and 49 homicides occurred each day. Motor vehicle injury deaths were more likely to occur on Saturdays and Sundays and least likely to occur on Tuesdays. The highest number of suicides occurred on Mondays and Tuesdays and the lowest on Saturdays. Homicides peaked on Sundays, followed by Saturdays; homicides were less likely to occur on weekdays.
The Elements of Physiological Physics. An Outline of the Elementary Facts, Principles and Methods of Physics; and their Application in Physiology.
Authors: None C. E. W.
Journal: JAMA (1884)

The title of this work sufficiently explains the nature of its contents. It is designed as a manual for the student of medicine, an auxiliary to his text-book in physiology, and would be particularly useful as a guide to his laboratory experiments, if he should have occasion to try any. It will be found of great value to the practitioner, particularly the general practitioner of fair education in physics and physiology, but who has become a little rusty. For instance he may be going to purchase a microscope and to sharpen up a bit on the principles of optics, or he is to write a paper on the relation of presbyopia and procreation, and would like to remember a little something about the physics of the eye. Here in very short space he will find the very facts and principles that he has forgotten. The book is of particular
NATHAN SMITH DAVIS, M.D.
Journal: JAMA (2004)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Dysphagia in a patient with Hodgkin's disease
Authors: B. W. Trotman
Journal: JAMA (1980)

DYSPHAGIA owing to lymphomatous involvement of the esophagus is uncommon and usually occurs late in the course of the disease, followed by death within six to 12 months.<sup>1,2</sup>A patient with Hodgkin's lymphoma initially manifested dysphagia. The diagnosis was suspected by the presence of Sternberg-Reed cells in the exfoliative cytological examination of the esophagus and confirmed by a lymph node biopsy specimen. We emphasize the importance of exfoliative cytology and the careful approach to management and staging of this uncommon clinical presentation. <h3>Report of a Case</h3> A 33-year-old man was admitted to the Hospital of the University of Pennsylvania complaining of progressive dysphagia and weight loss for the past five months. The patient was healthy until 12 months before admission when he experienced occasional nocturnal nausea relieved by bilious vomiting. An upper gastrointestinal (GI) tract series was normal at that time, and his symptoms subsided spontaneously over the next
A multicenter study on the prognosis of fulminant viral hepatitis: Early prediction for liver transplantation
Authors: Y Takahashi
Journal: Hepatology (1994)

To determine the risk of death at an early stage of fulminant viral hepatitis, we created severity indexes drawn from clinical data on the day of development of encephalopathy in 128 patients with fulminant hepatitis B and 103 with fulminant hepatitis non-A, non-B. In fulminant hepatitis B, the risk score was 2.75×BL+2.75×BR+2.7×AG+2.3×WB+1.67×CD+1.56×AL−0.098×PR−0.88, where BL is 1 if total bilirubin is higher than 20 mg/dl, BR is 1 if the ratio of total to direct bilirubin exceeds 2.2, AG is 1 if age is above 40 yr, WB is 1 if white blood cell count is less than 4,000 cells/mm3 or more than 18,000 cells/mm3, CD is 1 if a hazardous disease coexists and AL is 1 if ALT is less than 100 times the upper limit of normal (otherwise all are 0), and PR is prothrombin time (percentage of normal value). Using a cutoff score of 0, we found the positive predictive value, negative predictive value and predictive accuracy to be 0.90, 0.86 and 0.89, respectively. Sensitivity and specificity were 0.94 and 0.77, respectively. In fulminant non-A, non-B hepatitis, the risk score was 2.66×BR+2.25×BL+2.24×DI+2.05×AL ± 1.38×AG+0.00021×WB−6.33. BR is 1 if the ratio of total to direct bilirubin is more than 1.5, BL is 1 if total bilirubin is higher than 15 mg/dl, DI is 1 if the duration of illness before encephalopathy is less than 4 days or more than 12 days, AL is 1 if the ALT level exceeds 40 times the upper limit of normal and AG is 1 if age exceeds 50; otherwise all variables are 0. WB is WBC count per cubic millimeter. Positive predictive value, negative predictive value and predictive accuracy were 0.92, 0.80 and 0.89, respectively. Sensitivity and specificity were 0.95 and 0.70, respectively. These prediction equations were validated prospectively on a population of testing samples comprising 52 patients with fulminant hepatitis B and 47 with fulminant non-A, non-B hepatitis. Positive predictive values were 0.92 and 0.92, negative predictive values were 0.71 and 0.78 and predictive accuracies were 0.87 and 0.89 for patients with fulminant hepatitis B and fulminant non-A, non-B hepatitis, respectively. They may be used for selecting candidates for liver transplantation and for evaluating efficacy of a new therapy. (HEPATOLOGY 1994;19:1065–1071.)
Impact of Hypomethylating Agent Therapy in Myelodysplastic Syndromes with Chromosome 3 Abnormalities
Authors: David Sallman, Guillermo Garcia-Manero, Elias Jabbour, Mikkael A. Sekeres, Amy E. DeZern, David P. Steensma, Gail J. Roboz, John Barnard, Najla H. Al Ali, Cassie Zimmerman, Sherry Pierce, Denise Batista, Jeffrey E Lancet, Eric Padron, Jaroslaw P. Maciejewski, Alan F. List, Hagop M. Kantarjian, Rami S. Komrokji
Journal: Blood (2015)
Diseases of the Chest, Chicago
Journal: JAMA (1969)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
CPR
Authors: Clifton R. Cleaveland
Journal: Annals of Internal Medicine (1991)

On Being a Doctor1 October 1991CPRClifton R. Cleaveland, MDClifton R. Cleaveland, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-115-7-570 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe week had been tiring and discouraging—more long-term patients than usual had come to my office with illnesses for which I could do little but empathize and palliate. Aged men and women with fading intellects, emphysemic men slowly fading on continuous oxygen, a young woman with rapidly progressive motor neuron disease—I felt progressively stymied and ineffectual, longing for some more acute situation in which I could work toward a cure.I sought respite at a weekend showing of the new movie version ofHamlet. The reviews had been enthusiastic, and I was prepared for a cinematic treat. Thirty minutes passed,... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Chattanooga, TN 37422 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byImproving Cardiac Resuscitation in the CommunityNeil A. Solomon, MD 1 October 1991Volume 115, Issue 7Page: 570-571KeywordsCardiopulmonary resuscitationMotor neuronsOxygen Issue Published: 1 October 1991 Copyright & Permissions© 1991 American College of PhysiciansPDF downloadLoading ...
Aneurysm of the internal pudendal artery. A resected aneurysm from a previously unreported site
Authors: E. H. Pierce
Journal: JAMA (1968)

No previously reported aneurysm of the internal pudendal artery was found on review of the literature. A high index of suspicion is necessary for any diagnosis. "Egg shell" crepitation is one physical sign of an aneurysm. The use of a pediatric stethoscope in an unusual place confirmed the bruit and diagnosis of aneurysm.
Physician-patient communication. A key to malpractice prevention
Authors: W. Levinson
Journal: JAMA (1994)

What factors put physicians at risk for being sued? This is a vital question to practicing physicians since being named in a malpractice suit or, worse yet, going to court is an emotionally distressing event. A suit can lead to personal isolation, humiliation, depression, and even physical illness for physicians.<sup>1,2</sup>Understanding malpractice risk factors is also important to malpractice insurance companies, hospitals, and health care systems that seek to provide high-quality care while minimizing their liability and financial risk. See also pp 1583 and 1588. This issue of<i>JAMA</i>contains two articles that explore the relationship between physicians' malpractice claims history and two potential risk factors: quality of medical care and interpersonal communication skills. The study by Entman et al<sup>3</sup>examined the relationship between malpractice claims history of Florida obstetricians and the quality of the clinical care they provided to patients 5 to 10 years after the claims.