tbuckley/cabot-search huggingface dataset:
WILL THE WISCONSIN PURE FOOD LAW BE EMASCULATED?
Journal: JAMA (2010)

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Consortium Launches Genotyping Effort
Journal: Cancer Discovery (2013)

Abstract Hundreds of researchers have joined together in a large-scale cancer genotyping project focused on lung, breast, ovarian, prostate, and colorectal cancers. The OncoArray Consortium plans to perform germline genotyping of 425,000 blood samples pooled from consortium members by July 2014, using a custom genotyping chip that includes 530,000 single nucleotide polymorphisms.
The Assay of Galactokinase and Galactose-1-Phosphate Uridyl Transferase Activity in Human Erythrocytes
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Phospholipase A<sub>2</sub> in inflammatory bowel disease
Authors: T BERTSCH, J AUFENANGER
Journal: Gut (1997)

Editor,—Increased release of pro-inflammatory eicosanoids such as prostaglandin E2 and thromboxane B2 from mononuclear cells occurs during relapse in patients with inflammatory bowel disease (IBD).1 The key enzyme in eicosanoid synthesis is phospholipase A2(PLA2). Raised serum concentrations of the PLA2group II isoenzyme can be detected by immunoassay during the acute stages of IBD.2 We read with interest the recent article by Peterson et al about the role of a phospholipase A2 activating protein, PLAP ( Gut 1996; 39: 698–704). The authors showed clearly that PLAP can be detected in monocytes and granulocytes originating from intestinal mucosa of patients with Crohn’s disease and ulcerative colitis. In addition to this finding, extracellular deposits of PLAP antigen were associated with blood vessels and oedematous fluid from the inflamed tissue. Peterson et al postulated that PLAP may be involved in increasing PLA2 activity with consecutive eicosanoid generation in IBD. We propose a further possible mechanism of PLA2 activation during acute IBD in which the pro-inflammatory cytokine interleukin-6 … Professor Peterson.
The Milroy Lectures on the Natural History and Affinities of Rheumatic Fever: Delivered before the Royal College of Physicians of London, March, 1895
Authors: A. Newsholme
Journal: BMJ (1895)

Tz BRtnsTE 581 muscular fibres in the stroma, and to the formation of fibrous connective tissue, and this may in some.instances extend through the substance of the gland.The inference, therefore, from the case I have related is, that these structural.changes in the enlarged prostate eighteen days after bilateral castration are preliminary to the ultimate atrophy of the glandular tubules, and to the con- version of.the prostate into-a.small,firm, and fibrous mass, containing only remnants of the tubules, and but few traces of its muscular fibres.Changes similar in many respects to those ;described above as occurring after castration in man take place in the prostate of a dog after double castration.Thus in.June, 1890, I castrated, while resid,ng in Paris, a hound 3 to 4 years old, and three weeks (twenty-one days) after-the animal, was killed.In the gland, which was obviously small for so large
Surgical Statistics
Authors: J. Spence
Journal: BMJ (1880)

THE birds are divided into three primary divisions or groups.Of these, the Saururae is the oldest, and contains only one species, the archbeo- pteryx.This bird possessed many reptilian characters; its tail was long and pointed, and the quills of the tail were obliquely set.It had two digits, with a claw on each, the metacarpals being free and distinct from each other, showing in this respect a marked difference from the birds now existing.The next group-the Ratitaz-of which several speci- mens still exist in the ostrich tribe and apteryx, possess flat sterna and rudimentary wings, and in most the number of toes are diminished, the ostrich having only two.The last group is the Carinafa?, which possess well developed wings, and the power of flight is in some, such as the frigate bird, remarkably strong.The Ratilea have undoubtedly existed for a long period, as they are of a low and ancient type.Many of the extinct forms were of great size, as, for examiiple, the dinornis, which rivalled the giraffe in height, a character often indicative of low type and ancientness.Those birds possess no power of flight'; the wings are rudimentary, and there is no glenoid cavity, tr, when present, is only slightly indicated.In all Ratita-the hind limbs are very strongly developed and muscular.The sense of sight is very strong.The size of these animals, especially of the extinct forms, seems to have been the mechanical cause of the wings not being developed so as to enable them to fly.Several of the birds of the carinate type now existing are probably descended from parents which at an earlier period were of much larger size.Corn- crakes were.till a short time ago, as large as turkeys, and even cassa- waries, in New Zealand.This is the case, also, with other birds, as we find that doves larger than our gallinaceous poultry existed for- merly in the iATadascene Islands; but, in these latter, the keel of the sternum was dliminished in size, and also the wings, so that the power of flight was imlpaired.In the chalk-formations, birds are fotund with teeth which have had in some instances sheathed sockets.These are relicts of tht-reptilian form retained in ancient birds.In recent birds,
"New Home for New York Academy of Medicine."
Journal: JAMA (1925)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE INDEX.
Journal: JAMA (1907)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Fall
Authors: Larry G. McLain
Journal: JAMA (1987)

I have been involved in teaching residents and medical students for some years, and I spend a good deal of time going over the usual concerns in my mind. Will my slides be ready in time for the residents' lecture? How many students can I effectively advise next year? Have I fairly filled out the student evaluation forms? Will the scheduled lecturers be on time (or informative)? Are the students really learning anything anyway? Do my efforts and those of the other physician-teachers really matter? These questions were far from my mind on a sparkling fall morning as I hammered and sawed, repairing the roof of the barn on our Wisconsin farm, a dilapidated structure older than the 69-year-old silver-haired gentleman working on the other side. The serenity of the morning was abruptly ended by a loud crackling noise from the opposite side of the barn. I quickly got down
Differential tenofovir alafenamide (TAF) adoption in HBV-infected populations; assessment of care in US clinical practice
Authors: Michael Curry, Ho Bae, Douglas Dieterich, Victor Ankoma-Sey, Rajender Reddy, Calvin Pan, Hie-Won Hann, Myron Tong, W. Ray Kim, Paul Kwo, Lynn Frazier, Kimmi Cox, Scott Milligan, Nezam Afdhal
Journal: Journal of Hepatology (2020)
Television Violence
Journal: JAMA (1993)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Progress Toward Poliomyelitis Eradication—Pakistan, 1994-1998
Journal: JAMA (1999)

Since the 1988 World Health Assembly resolution to eradicate poliomyelitis by 2000, polio cases reported globally have decreased by approximately 85%. Despite a strong commitment to polio eradication, polio remains endemic in Pakistan. In 1997, Pakistan reported 1147 polio cases, representing widespread poliovirus circulation nationally and constituting 22% of cases reported worldwide. However, surveillance and laboratory data from 1998 indicate that previous widespread poliovirus circulation was geographically localized for the first time. This report describes polio eradication activities in Pakistan, including the impact of routine and supplementary vaccination on polio incidence.
Interpretación en la práctica de los análisis clínicos.
Journal: JAMA (1931)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
As nation's long, hot summer drags on, so does war against forms of air pollution
Authors: C. Marwick
Journal: JAMA (1988)

THE AIR POLLUTION WAR could be going better than it is. But at the moment the battle is being more successfully fought against carbon monoxide than it is against ozone. The Environmental Protection Agency says that the number of areas having levels of ozone higher than the allowed minimum has increased since the last estimate was made. However, the agency says, the number of areas with excessive amounts of carbon monoxide has decreased. Still, Environmental Protection Agency officials say, 44 states and the District of Columbia have places where ozone and carbon monoxide levels are in excess of those laid down by the Clean Air Act. <h3>Physicians' Role</h3> As to what physicians can do to help patients exposed to such levels of pollution, Samuel V. Spagnolo, MD, director, Division of Pulmonary Diseases and Allergy, George Washington University School of Medicine, Washington, DC, said: "Pollution at these levels irritates the trachea
Who pays for published research?
Authors: M. D. Stein
Journal: JAMA (1993)

<h3>Objective.</h3> —To determine the extent of unfunded research published in major medical journals. <h3>Design.</h3> —Review of original research completed in the United States and published in 23 official journals of internal medicine and neurology during 1 month in 1991. Investigators were contacted to confirm lack of funding. <h3>Main Outcome Measure.</h3> —Percentage of unfunded, published original research. <h3>Results.</h3> —One hundred ninety-six articles were evaluated. There was at least one unfunded study in 78% of journals. Forty-five published studies (23%) were unfunded. Among those 45 studies, 7% were clinical trials, 9% were cohort studies, 18% were cross-sectional or case-control studies, 53% were case series, and 13% were surveys. Thirteen unfunded studies involved procedures that presumably were performed for research purposes and not as part of routine patient care. <h3>Conclusions.</h3> —Nearly one quarter of original research published in major medical journals was unfunded. Seven percent of published research involved direct clinical costs that were not accounted for by the investigators. These costs may have been passed on to study participants or third-party payers. (<i>JAMA</i>. 1993;269:781-782)
LYMPHATISM AS A FAMILY DISEASE.
Journal: JAMA (1906)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Ovarian ablation (OA) in pre-menopausal women with early breast cancer prescribed 5 years tamoxifen (T) or T plus chemotherapy (CT)–results from the UK NCRI Adjuvant Breast Cancer (ABC) international trial of 2,144 patients
Authors: J. R. Yarnold, J. M. Bliss, H. Earl, D. George, D. Lawrence, S. H. Mortazavi, T. J. Perren, V. Raina, D. Spooner
Journal: Journal of Clinical Oncology (2004)
Primary prevention with metoprolol in patients with hypertension
Authors: J. Staessen, R. Fagard, A. Amery
Journal: JAMA (1988)

<h3>To the Editor.—</h3> We read with interest the recent article by Wikstrand and coworkers.<sup>1</sup>These investigators employed the Gehan-Wilcoxon nonparametric test for survival analysis and found in male hypertensive patients with diastolic blood pressures ranging from 100 through 129 mm Hg that total (<i>P</i>=.028) and cardiovascular (<i>P</i>=.012) mortality were reduced by metoprolol therapy compared with treatment with a thiazide diuretic. The 95% confidence interval for the reduction in total mortality at median follow-up (4.16 years) ranged from - 68% to -17%. However, the 95% confidence limits for the differences between the two treatment groups in cardiovascular mortality at median followup and in both total and cardiovascular mortality at the end of the study were not published. Using methods that were described previously<sup>2</sup>and the results published in Table 3 of the Metoprolol Atherosclerosis Prevention in Hypertensives Study,<sup>1</sup>we calculated these 95% confidence intervals. We confirmed that
Gray's Anatomy
Authors: J. E. Skandalakis
Journal: JAMA (1996)

Gray's Anatomy "Men of genius do not excel in any profession because they labour in it, but they labour in it, because they excel." William Hazlitt (1778-1830) The genius Henry Gray devoted his youth to anatomy. In 1858, at the age of 31, he published a book of 750 pages and 363 figures. I had the honor to review the 37th edition of<i>Gray's Anatomy</i>for this publication and now hold the 38th edition, a colossus of 2092 pages and 2768 illustrations. <i>Gray's Anatomy</i>began transforming its scope and visual impact in 1971. While the content is excellent, the overall organization is disarticulated and fragmented. I appreciate the color pages fronting each chapter, some graced with valuable statements of philosophy (see chapter 3). The blend of knowledge and skepticism of the 37th edition continues magnificently. I concur with editor Lawrence H. Bannister's assessment of the Queen of Medical Sciences today:
The molecular biology of medullary thyroid carcinoma. A model for cancer development and progression
Authors: B. D. Nelkin
Journal: JAMA (1989)

Medullary thyroid carcinoma (MTC) is an important human cancer for the study of molecular abnormalities that underlie initiation of neoplasia and subsequent cellular changes during tumor progression. This tumor can occur in different inherited forms, each mediated by autosomal dominant genetic events. Germline abnormalities on chromosome 10 are linked to at least one type of genetic MTC, multiple endocrine neoplasia type II. Our studies of chromosome 10 in DNA from MTC tumors failed to detect frequent loss of polymorphic DNA markers, suggesting that the genetic mechanisms involved in MTC development may be different from those for other inherited cancers such as retinoblastoma. During tumor progression of MTC, abnormalities develop in expression of the mature phenotype of the endocrine cell from which the tumor arises. In cell culture, chemical modulation or gene insertion can lead to partial correction of these defects in differentiation capacity by activating cellular signaling processes. These studies offer opportunities to dissect the molecular events that regulate endocrine cell differentiation, to determine the precise abnormalities that may underlie the initiation and tumor progression events in MTC and related cancers, and, thereby, to identify new targets for therapeutic intervention. (<i>JAMA</i>. 1989;261:3130-3135)