tbuckley/cabot-search huggingface dataset:
Gastroenterology, Baltimore
Journal: JAMA (1970)

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Pertussis in an Infant Adopted From Russia--May 2002
Journal: JAMA (2002)

On May 2, 2002, the North Carolina Department of Health and Human Services notified CDC about an infant aged 10 months adopted from Russia who had culture-confirmed pertussis diagnosed. On April 8, the adoptive parents picked him up in the orphan ward at hospital A in Bryansk and noticed that the child had upper respiratory congestion and cough. The adoptive parents reported that the infant had not received any vaccinations and that another infant living in the same room in hospital A had a severe cough. The adopted infant subsequently was examined by a local physician, who diagnosed his condition as a "cold," and the infant was taken to the U.S. Embassy in Moscow, where the parents were interviewed for an immigrant visa for the child.
Book Review Text-book of Embryology , by Frederick R. Bailey, formerly Adjunct Professor of Histology and Embryology, College of Physicians and Surgeons (Medical Department of Columbia University), and Adam M. Miller, Professor of Anatomy, The Long Island College Hospital. Fifth revised edition. William Wood and Company, New York. 687 pp. 1929. Price $7.00.
Journal: New England Journal of Medicine (1930)
Dopamine agonists for polycystic ovary disease?
Authors: E. R. Gonzalez
Journal: JAMA (1982)

Women with polycystic ovarian syndrome (PCOS) generally are treated with oral contraceptives, "fertility drugs" to induce ovulation, or—when all else fails—surgical wedge resection. But tentative clinical impressions now suggest that dopamine agonists used to treat hyperprolactinemia may become a therapeutic option for these patients. (For discussion of another use of dopamine agonist therapy, see "Galactorrhea Without Hyperprolactinemia" on page 593.) At the recent Endocrine Society meeting in San Francisco, Jon J. Pehrson, MD, a fellow in endocrinology and metabolism at Boston City Hospital, reported that the disease may entail alterations in dopaminergic control of prolactin secretion. Pehrson and Judith L. Vaitukaitis, MD, of Boston University School of Medicine, who is chief of endocrinology at the city hospital, found slightly elevated basal serum prolactin levels in about one third of 42 affected women (none of whom had pituitary tumors or congenital adrenal hyperplasia) during protracted amenorrhea or the early follicular phase
Rheumatoid Arthritis
Authors: G. B. Bluhm
Journal: JAMA (1974)

<h3>To the Editor.—</h3> I must take issue with the title, "Rheumatoid Disease Without Joint Involvement" (228:338, 1974). The authors state that during five years of clinical observation, the patient had "no significant arthritis." X-ray film changes commonly associated with early, mild, erosive rheumatoid arthritis were present, and such changes were observed by the authors two years after they dated the onset of the patient's "rheumatoid disease." Their point more appropriately refers to the mild degree of objective joint disease with severe systemic complications in the presence of rheumatoid nodules and rheumatoid factors, usually associated with severe progressive joint destruction. A less misleading title might be "Severe Systemic Rheumatoid Disease With Mild Joint Involvement." In the true absence of arthritis or residual joint changes compatible with previous active synovitis, a diagnosis of rheumatoid arthritis would not be justified.
THE IDENTIFICATION OF SPECIES IN BACTERIOLOGY.
Journal: JAMA (1906)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Smoking and the Nether Esophagus
Journal: JAMA (1971)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Interventional radiological treatments tested
Authors: A. A. Skolnick
Journal: JAMA (1997)

INTERVENTIONAL radiologists continue to set their sights on a widening variety of medical problems they hope can be effectively treated using new techniques that are less invasive than surgery. The results of clinical studies of several such new procedures were reported at the 22nd annual scientific meeting of the Society of Cardiovascular and Interventional Radiology (SCVIR), in Washington, DC, in March. Among the procedures were nonsurgical methods to treat infected spinal discs, uterine fibroid tumors, and end-stage liver disease in patients with cystic fibrosis and to repair ruptured aortic aneurysms and damaged spleens. While the results of the small trials look promising, most of the researchers cautioned that larger and longer follow-up studies are needed, particularly randomized trials to compare the outcomes of the new procedures with those of conventional surgical techniques. <h3>Patching Ruptured Aortas</h3> Patients who present with a ruptured aortic aneurysm have a high risk of not surviving
Thromboembolic disorders and oral contraceptives
Journal: JAMA (1969)

<h3>To the Editor:—</h3> Drill and Calhoun<sup>1</sup>differ from the British Medical Research Council<sup>2</sup>and from the British Committee on Safety of Drugs<sup>3</sup>in the conclusions that they draw from our work on the relationship between the use of oral contraceptives and the development of thromboembolism. This, we suggest, is because they have misunderstood or misinterpreted our findings. For example: They dismiss the results of Vessey and Doll's study<sup>4</sup>because it led to the conclusion that the hospital admission rate for "idiopathic" venous thrombosis in young married women not using oral contraceptives was 0.05 per 1,000 per year, a figure which "is so far out of line from other American and English statistics that it cannot be accepted as comparable." In fact, it is directly comparable with the figure of 0.5 per 1,000 in women who were using oral contraceptives but were otherwise similar, since exactly the
Identification of Vascular Endothelial Growth Factor (VEGF) Receptor-2 (Flk-1) Promoter/Enhancer Sequences Sufficient for Angioblast and Endothelial Cell-Specific Transcription in Transgenic Mice
Authors: Andreas Kappel, Volker Rönicke, Annette Damert, Ingo Flamme, Werner Risau, Georg Breier
Journal: Blood (1999)
Dinosaurs
Authors: Maria A. Basile
Journal: JAMA (2009)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The genetics of antibody production. Clinical implications
Authors: J. N. Goldman
Journal: JAMA (1984)

IN THE 1840s, Dr Henry Bence Jones published a description of an unusual protein found in the urine of a patient with a disease that was to become known as multiple myeloma or plasmacytoma.<sup>1</sup>(See glossary on page 787.) These "Bence Jones proteins" are now known to consist of the light chains of immunoglobulins and are but one of many protein abnormalities associated with multiple myeloma. Multiple myeloma results from the malignant proliferation of a clone of plasma cells that produce intact immunoglobulins or immunoglobulin fragments or both. The distinguishing feature of multiple myeloma is its association with a highly homogeneous population of immunoglobulin molecules (ie, monoclonal) rather than highly heterogeneous populations that are found in normal persons. Immunoglobulins are the most heterogeneous family of biologic molecules known. Plasmacytomas also occur in a variety of experimental animals, most notably in the mouse where the disease can readily be induced
TURKEY
Journal: JAMA (1928)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE PROTOZOON OF CANCER.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
MEDICAL EDUCATION AND THE RISE OF HOSPITALS
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 19304: Clinical Profile and Outcomes of Patients Undergoing Combined Heart and Liver Transplantation With Transthyretin Amyloidosis: A Report From the International Consortium on Cardiac Amyloid Transplantation (iCCAT)
Authors: Karla C Verkouw, Muthiah Vaduganathan, James R Stone, Mathew Maurer, Teresa De Marco, Van Selby, Jerry Estep, Jignesh Patel, Mazen Hanna, David Seldin, Mark Zucker, David Baran, Marc J Semigran
Journal: Circulation (2015)

Background: Orthotopic heart transplant (OHT) is an accepted treatment option for transthyretin amyloidosis (ATTR) patients with end-stage heart failure. The incremental survival benefit of adjunctive liver transplant remains poorly defined. Methods: We aim to describe the clinical profiles/prognoses of patients undergoing OHT/liver transplant compared with OHT alone. From January 1998 to May 2015, 42 of 48 ATTR patients being evaluated for OHT at 10 institutions underwent transplant and were included in the final analysis. Data were entered into an encrypted online database, Research Electronic Data Capture. The primary endpoint of post-OHT all-cause mortality was compared between 3 cohorts defined by transplant and mutation status using Kaplan-Meier survival analysis: OHT alone-wild type (WT) (n=12; Cohort A); OHT alone-ATTR mutation (n=21; Cohort B); and combined OHT/liver transplant (n=9; Cohort C). Results: Of those undergoing OHT, 12 (28.6%) were WT, 15 (32.5%) had a V122I mutation, 3 (7.1%) had a T60A mutation, 8 had other mutations, and 4 had unknown mutations. For the subset of 9 patients who underwent combined OHT/liver transplant (4 concurrently, 5 sequentially), the mutations were as follows: V122I (n=3), T60A (n=3), S23A (n=2), and Tyr77 (n=1). Baseline characteristics did not differ significantly across the 3 cohorts for age, sex, LV ejection fraction, and other demographic, clinical, and hemodynamic characteristics. Peripheral neuropathy was present in 2 (17%) of Cohort A, 7 (33%) of Cohort B, and 4 (44%) of Cohort C (p=0.08). Post-OHT all-cause mortality was similar across cohorts (log-rank P=0.218; Figure). Conclusions: This is the largest analysis of ATTR cardiac amyloidosis patients receiving heart and liver transplantation. ATTR patients receiving OHT/liver transplant versus OHT alone have similar median-term survival. The added survival benefit of liver transplantation to OHT in ATTR mutant patients should be investigated further.
Update to CDC’s &lt;emph type="ital"&gt;Sexually Transmitted Diseases Treatment Guidelines, 2010&lt;/emph&gt;: Oral Cephalosporins No Longer a Recommended Treatment for Gonococcal Infections
Journal: JAMA (2012)

Gonorrhea is a major cause of serious reproductive complications in women and can facilitate human immunodeficiency virus (HIV) transmission. Effective treatment is a cornerstone of U.S. gonorrhea control efforts, but treatment of gonorrhea has been complicated by the ability of Neisseria gonorrhoeae to develop antimicrobial resistance. This report, using data from CDC's Gonococcal Isolate Surveillance Project (GISP), describes laboratory evidence of declining cefixime susceptibility among urethral N. gonorrhoeae isolates collected in the United States during 2006-2011 and updates CDC's current recommendations for treatment of gonorrhea. Based on GISP data, CDC recommends combination therapy with ceftriaxone 250 mg intramuscularly and either azithromycin 1 g orally as a single dose or doxycycline 100 mg orally twice daily for 7 days as the most reliably effective treatment for uncomplicated gonorrhea. CDC no longer recommends cefixime at any dose as a first-line regimen for treatment of gonococcal infections. If cefixime is used as an alternative agent, then the patient should return in 1 week for a test-of-cure at the site of infection.
ACCIDENTAL INFECTION WITH BLASTOMYCOSIS.
Journal: JAMA (1903)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Folate Deficiency
Authors: Gilbert H. Glaser
Journal: JAMA (1972)

<h3>To the Editor.—</h3> Dr. Herbert's contention that our patient had neurological damage secondary to vitamin B<sub>12</sub>deficiency is made in the face of contrary evidence that deserves repetition and further elaboration. One week prior to hospital admission in January 1970, the patient complained of fatigability and other nonspecific symptoms and was given an injection of cyanocobalamin by her local physician. Despite this, she became progressively weaker and was ultimately unable to stand. When she finally became semicomatose, she was rushed to the hospital. On entering the hospital, her serum B<sub>12</sub>level was found to be in excess of 2,000μμ/ml. The reticulocyte count, which should have been at a peak if her anemia was secondary to vitamin B<sub>12</sub>deficiency, was only 0.4%. During her first week in the hospital, further daily injections of cyanocobalamin failed to induce reticulocytosis or neurological improvement. Reticulocytosis appeared on the second day of
Massachusetts Medical Society
Authors: Charles D. Cook, Robert J. Haggerty
Journal: New England Journal of Medicine (1960)

TOXIC HAZARDS*Mycetismus (Amanita Phalloides)†With the onset of spring, it is likely that certain people will again be tempted to indulge in the gastronomic pleasures of self-picked mushrooms. The following case illustrates the hazards involved:At 4 a.m. on September 16, 1949, a 9-year-old boy had a sudden attack of nausea and projectile vomiting (but no diarrhea) followed within 12 hours by drowsiness. During the preceding evening the family had eaten mushrooms, which they had picked in the country around Putnam, Connecticut, and had considered safe because they "did not tarnish a silver coin." The mushrooms were subsequently identified . . .
Swallowable capsule technology: current perspectives and future directions
Authors: K. Twomey
Journal: Endoscopy (2009)

We would like to thank Drs Sanchez-Yague and Nguyen-Tang for their comments on our article describing swallowable capsule technology and the recent advances in this area [1]. In their letter, capsule image acquisition and processing is highlighted as an important topic with many exciting developments. We agree that this is an important area and that there is much ongoing research and development activity. The authors give specifications on the different capsule endoscopes that are available. This includes the different variants of the PillCam product from Given Imaging, and the EndoCapsule, MiRo, and OMOM, each of which has its own advantageous features. Developments in advanced endoscopic imaging are also mentioned. In recent times, there have been a number of useful review articles on capsule endoscopes [2] [3] [4] [5]. However, due to the rapidity of new developments, an updated review dedicated to capsule endoscopes would be interesting.