tbuckley/cabot-search huggingface dataset:
Heroin Addiction
Authors: Robert H. Moser
Journal: JAMA (1974)

Her name was Lilly or Sally. She was tough, beautiful, angry, and terribly sick. Through the rage of fever and delirium she screamed that she was a "prostitute and a junky—and damned proud of it!" She was barely 19, and she had<i>Staphylococcus aureus</i>growing on her tricuspid valve. We cured her with penicillin—in doses so timid that a contemporary clinician would wince in disbelief. She never did smile, but when she left the ward, she put two pink and green doilies wrapped in tissue paper on the nurse's desk—for me. They had been crocheted in secrecy with hands encumbered by needles and tubes. It was a shy expression of gratitude for nonjudgmental kindness. The penicillin had sterilized her valve. That was in 1947, my first exposure to the nether world of narcotic addiction. In 1944, my mentor, Hugh Hussey, and some colleagues<sup>1</sup>published an unusual report. Of four heroin
LONDON
Journal: JAMA (1933)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Archives of Pathology, Chicago
Journal: JAMA (1970)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Incorrect Statement
Journal: JAMA (1987)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
CORRELATION OF BASAL METABOLIC RATE WITH PULSE RATE AND PULSE PRESSURE
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
IMMU-08. IMMUNOPHENOTYPING OF PEDIATRIC BRAIN TUMORS: CORRELATING IMMUNE INFILTRATE WITH HISTOLOGY, MUTATIONAL LOAD, AND SURVIVAL
Authors: Ashley Plant, Shohei Koyama, Claire Sinai, Isaac Solomon, Gabriel Griffin, Glenn Dranoff, Mark Kieran, Jerome Ritz
Journal: Neuro-Oncology (2017)

There is little known regarding the immune infiltrate present in pediatric brain tumors and how this compares to what is known about histologically similar adult tumors and its correlation with survival. Here, we provide a descriptive analysis of the immune infiltrate of 22 fresh pediatric brain tumor tissue samples of mixed diagnoses and 40 peripheral blood samples. Samples were analyzed using a flow cytometry panel containing markers for immune cell subtypes, costimulatory markers, inhibitory signals, and markers of activation. This was compared to the standard method of immunohistochemistry (IHC) for immune markers for 89 primary pediatric brain tumors. Both flow cytometry and IHC data did not correlate with the grade of tumor and IHC data was not significantly associated with survival for either low grade or high grade gliomas. There is a trend towards a more immunosuppressive phenotype in higher grade tumors including more regulatory T cells and B cells. Both PD1 and PDL1 were present in only a small percentage of the tumor infiltrate. Elisa assays for NKG2D soluble ligands was also negative for all tumor types. T cell receptor sequencing revealed up to 10% clonality of T cells in tumor infiltrates and no significant difference in clonality between low and high grade gliomas. We have shown the immune infiltrate of pediatric brain tumors does not appear to correlate with grade or survival for a small sample of patients. Further research and larger studies are needed to fully understand the interaction of pediatric brain tumors and the immune system.
2011 ACCF/AHA/HRS Focused Update on the Management of Patients With Atrial Fibrillation (Update on Dabigatran)
Authors: L. Samuel Wann, Anne B. Curtis, Kenneth A. Ellenbogen, N.A. Mark Estes, Michael D. Ezekowitz, Warren M. Jackman, Craig T. January, James E. Lowe, Richard L. Page, David J. Slotwiner, William G. Stevenson, Cynthia M. Tracy
Journal: Journal of the American College of Cardiology (2011)
Malignant Hyperthermia
Authors: Oscar M. Jardon
Journal: JAMA (1980)

<h3>To the Editor.—</h3> The inherited muscle disorder known as malignant hyperthermia should be renamed, as this term is confusing and relates to only one manifestation of the syndrome. Elemér K. Zsigmond, MD (243:513, 1980), suggested "acute familial peranesthetic rhabdomyolysis." This tends to be slightly cumbersome and restricts definition to peranesthetic manifestation. Our studies of this syndrome suggested that the symptoms arise from many types of stress other than anesthesia.<sup>1,2</sup>Included are intolerance to heat and exercise, emotional stress, trauma, and cramping (transport related problems similar to porcine stress syndrome).<sup>3,4</sup> Since this disease appears to be related to stress, including that caused by anesthesia, it might be more appropriate and descriptive to refer to it simply as "human stress syndrome." This is less cumbersome and easy to remember and encompasses the more important aspect of the disease—stress of many kinds, including anesthesia as an exciting factor.
Books Received
Journal: JNCI Journal of the National Cancer Institute (1971)

Journal Article Books Received Get access Ballantyne AJ, Michaelson IC: The Fundus of the Eye. Baltimore, Williams & Wilkins Co., 1970, 736 p, $46.50. Morphology of Experimental Respiratory Carcinogenesis (Nettesheim P, Hanna MGJrDeatherage JWJr eds.). Oka Ridge, U.S. Atomic Energy Commission, 483 p, $6.00. Begani R: Terapia medica dell'adenoma prostatico (prostatic neoplasms—drug therapy). [Torino] Minerva medica, 1970, 65 p. Biology of Large RNA Viruses, vol 16 (Barry RD, Mahy WJ, eds.). London, New York, Academic Press Inc., 1970, 736 p, 24.40. Boie D: Mistel und Krebs, eine anthroposophisch-medizinische Studie zur Mistel-Therapie des Krebses (anthroposophy—neoplasms and drug therapy). [Stuttgart] Verlag Freies Geistesleben [ 1970], 143 p. Centre d'Etude de l'Énergie nucléaire (penetration and fate of exogenous DNA into cells of normal and irradiated mammalian tissues). Mol, 1970, 16 p. Diagnose und Therapie der mesenchymalen Tumoren und Hyperplasien des Mund-, Kiefer- und Gesichtsbereichs (facial, jaw, and mouth neoplasms). Stuttgart, Thieme, 1970, 290 p. Die Therapie des Mundhbählenkarzinoms (mouth neoplasm therapy). Stuttgart, Thieme, 1968, 278 p. Fritsch RS: Virusinduzierte Myelosen der Maus, elektronenmikroskopische und morphometrische Untersuchungen, vol 7 (leukemia, myelocytic, etiology). Stuttgart, Fischer, 1971, 128 p. Guerrier Y, et al: Les Tumeurs nerveuses en oto-rhinolaryngologie, vol 5 (nose neoplasms). Montpellier, Centre de recherches Sympharm, 1969, 6.34. Human Resources Research Organization, vol 10 (Fink CD, ed.). Alexandria, 1970, 36 p. Lucas RB: Pathology of Tumors of the Oral Tissues, vol 8. London, Churchill, 1964, 316 p, 14.25. Novikova LA, Grigorova TM: Khorioepitelioma matki (klinika i lechenie) (choriocarcinoma and uterine neoplasms). Leningrad, Meditsina, 1968, 158 p, 1.50. Ott G: Fremdkärpersarkome, vol 10 (foreign bodies—sarcoma, experimental—etiology). Berlin, New York, Springer-Verlag, 1970, 118 p. Saenko AI: Khirurgicheskoe lechenie rasprostranennykh form raka zheludka (stomach neoplasms—surgery). Frunze, Kyrgystan, 1967, 227 p, 1.50. Solomidès J: La physiatrie et les physiatrons synthétiques (neoplasms—therapy, physical medicine). Sceaux, Edition de l'Institut Solomidès, 1969, 292 p, 5.43. Tajima M: Special Cytodiagnosis, vol 31. Tokyo, Nakayama [ 1970], 372 p, $41.66. Viral Tumorigenesis Report, vol 5. Bethesda, National Cancer Institute and Smithsonian Institution. Wisconsin Alumni Research Foundation: Madison, 1969, 129 p. JNCI: Journal of the National Cancer Institute, Volume 46, Issue 6, June 1971, Pages 1361–1362, https://doi.org/10.1093/jnci/46.6.1361 Published: 01 June 1971
Tic-like Dyskinesias
Journal: JAMA (1976)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Relationship between multicentric reticulohistiocytosis and tuberculosis
Authors: K. D. Gold
Journal: JAMA (1977)

Some cases presently classified as multicentric reticulohistiocytosis may represent unusual manifestations of tuberculosis. Antituberculous chemotherapy may be justified in patients who have clinical and histopathologic evidence of multicentric reticulohistiocytosis in association with a positive tuberculin skin test. (<i>JAMA</i>237:2213-2214, 1977)
THE FEMALE SEX HORMONE
Journal: JAMA (1926)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Stimulation of natural killer cells with a CD137-specific antibody enhances trastuzumab efficacy in xenotransplant models of breast cancer
Authors: Holbrook E. Kohrt, Roch Houot, Kipp Weiskopf, Matthew J. Goldstein, Ferenc Scheeren, Debra Czerwinski, A. Dimitrios Colevas, Wen-Kai Weng, Michael F. Clarke, Robert W. Carlson, Frank E. Stockdale, Joseph A. Mollick, Lieping Chen, Ronald Levy
Journal: Journal of Clinical Investigation (2019)
Leucotomy
Authors: S. A. Gueukdjian
Journal: BMJ (1952)

Three examples of non-syphilitic paroxysmal cold haemoglobinuria (PCH) in children are described which occurred, within a period of 16 days, in association with a febrile illness. No definite viral aetiology or obvious epidemiological association could be established. A Donath-Landsteiner antibody of anti-P specificity was demonstrated in all three patients. The serological aspects of PCH are critically discussed.
THE ETIOLOGY OF VALVULAR DISEASE OF THE HEART.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
PTU-171 Oestrogen plays a critical role in murine epithelial healing in a buccal model of reflux injury
Authors: B T Theron, N Trudgill
Journal: Gut (2012)

<h3>Introduction</h3> Severe oesophagitis, oesophageal adenocarcinoma (OAC) are more common in men and post-menopausal women. Female sex hormones may protect pre-menopausal women from gastro-oesophageal reflux mediated mucosal damage, delaying the onset of BO and development of OAC in women. We have demonstrated more rapid mucosal healing and less inflammatory response in females in a murine buccal model of reflux injury. We have used a model comparing intact female mice with oestrogen deprived mice (by removal of their ovaries) to determine if this effect may be oestrogen driven. <h3>Methods</h3> Female mice (C57 strain) were divided into three groups of 5: ovariectomised (OVX), OVX with oestrogen replacement (OVX+E) (50 μg oestradiol per day dorsal implants) and intact females. 1.5 mm buccal ulcers were induced using a punch biopsy and treated with 1 M hydrochloric acid. Wounds were harvested at day 4. Wound planimetry and immunohistochemistry for macrophages and neutrophils were compared in a blinded fashion. <h3>Results</h3> Results: Re-epithelialisation was greatest in the intact group (mean 0.88 mm SEM ± 0.22) compared to the OVX (0.51 mm ± 0.13) or OVX+E (0.79 mm ± 0.12) groups. The difference between intact and OVX groups was statistically significant (p=0.04). Neutrophil wound infiltration (cells/wound area) was greater in the OVX group (1842±75) than the intact group (1279±169, p There was a greater number of macrophages in the OVX wounds (1556±128) than both OVX+E (984±95 (p=0.02) and the intact group (1026±91, p=0.01). <h3>Conclusion</h3> Lack of systemic oestrogen delays mucosal healing in buccal wounds. This may explain gender differences in the oesophageal epithelial response to gastro-oesophageal reflux injury. <h3>Competing interests</h3> None declared.
Allied Health Education and Accreditation
Authors: William R. Burrows
Journal: JAMA (1986)

<h3>MUTUAL SUPPORT: AMA AND THE ALLIED HEALTH PROFESSIONS</h3> Allied health professionals are described in US Public Law 99-129 as persons who share in the responsibility for the delivery of health care services or related services, including services relating to the identification, evaluation, and prevention of diseases and disorders; dietary and nutrition services; health promotion services; rehabilitation services; or health systems management services. The article that follows discusses the goals and methods of various bodies that collaborate under the umbrella of the Committee on Allied Health Education and Accreditation (CAHEA) to accredit allied health educational programs in a rapidly changing health care environment. For more than 50 years, the American Medical Association (AMA) and its members have recognized the value of participating extensively in various activities to promote quality education for allied health personnel. Many physicians are involved in allied health educational programs, as well as in the accreditation review process
The Descent
Authors: Neil L. Schechter
Journal: JAMA Pediatrics (2014)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Pediatrics HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Pediatrics journal
Snake venom poisoning in the United States. Experiences with 550 cases
Authors: F. E. Russell
Journal: JAMA (1975)

SNAKE venom poisoning is a medical emergency requiring immediate attention and the exercise of considerable judgment. Approximately 45,000 snakebites occur each year in the United States, of which almost 8,000 are inflicted by venomous snakes, and about 6,800 of these are reported.<sup>1,2</sup>During the past five years, the number of deaths from snake venom poisoning in this country has not exceeded 12 each year. Approximately 20% of all bites by venomous snakes in the United States show no evidence of envenomation; that is, the offending reptile bites but does not inject venom or ejects it onto the skin during a superficial strike. This percentage is even higher with elapids (cobras and corals, among others), and there is no doubt that many of the "cures" described in the literature<sup>3</sup>can be ascribed to the fact that no envenomation took place during the biting. Thus, it is important that the
Drug Impairment
Journal: JAMA (1998)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal