Comparative Effectiveness of Routine Invasive Coronary Angiography for Managing Unstable Angina
Authors: Vijaya Sundararajan, Sara Vogrin
Journal: Annals of Internal Medicine (2017)

Letters5 December 2017Comparative Effectiveness of Routine Invasive Coronary Angiography for Managing Unstable AnginaVijaya Sundararajan, MD, MPH and Sara Vogrin, MBBS, MBiostatVijaya Sundararajan, MD, MPHSt. Vincent's Hospital, University of Melbourne, Fitzroy, Victoria, Australia (V.S., S.V.)Search for more papers by this author and Sara Vogrin, MBBS, MBiostatSt. Vincent's Hospital, University of Melbourne, Fitzroy, Victoria, Australia (V.S., S.V.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/L17-0522 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:We thank Dr. Oshima and colleagues for their query about whether we adequately accounted for unmeasured confounders in our analysis. As described in the Statistical Analysis, Sensitivity Analysis, and Discussion sections and in Figure 4 of our article, we tested whether 1 or more unmeasured confounders might negate the observed effect size of ICA. We used the example of whether greater provision of optimal medical therapy (OMT) to the group that received ICA versus the comparison group could account for part or all of the observed effect size in our original analysis and will expand on that example.... Reference1. Yan AT, Yan RT, Tan M, Huynh T, Soghrati K, Brunner LJ, et al; Canadian ACS Registries Investigators.. Optimal medical therapy at discharge in patients with acute coronary syndromes: temporal changes, characteristics, and 1-year outcome. Am Heart J. 2007;154:1108-15. [PMID: 18035083] CrossrefMedlineGoogle Scholar2. Chernomordik F, Sabbag A, Tzur B, Kopel E, Goldkorn R, Matetzky S, et al. Cardiac rehabilitation following an acute coronary syndrome: trends in referral, predictors and mortality outcome in a multicenter national registry between years 2006-2013: report from the Working Group on Cardiac Rehabilitation, the Israeli Heart Society. Eur J Prev Cardiol. 2017;24:123-32. [PMID: 27881758] doi:10.1177/2047487316680692 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: St. Vincent's Hospital, University of Melbourne, Fitzroy, Victoria, Australia (V.S., S.V.)Disclosures: Authors have disclosed no conflicts of interest. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M16-2420. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoComparative Effectiveness of Routine Invasive Coronary Angiography for Managing Unstable Angina Sara Vogrin , Richard Harper , Elizabeth Paratz , Andrew MacIsaac , Jodie Burchell , Belinda Smith , Anthony Scott , Jongsay Yong , and Vijaya Sundararajan Comparative Effectiveness of Routine Invasive Coronary Angiography for Managing Unstable Angina Yasuo Oshima , Yuko Morishima , Koichi Ono , Masaya Hirano , and Katsunori Suzuki Metrics 5 December 2017Volume 167, Issue 11Page: 836KeywordsAcute coronary syndromeAngiographyCardiac rehabilitationConflicts of interestDisclosureHazard ratioOdds ratioRelative riskUnstable angina ePublished: 5 December 2017 Issue Published: 5 December 2017 Copyright & PermissionsCopyright © 2017 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...