tbuckley/cabot-search huggingface dataset:
PHYSICAL EXAMINATIONS UNDER NEW YORK'S NEW LAW.
Journal: JAMA (1894)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
MISCELLANEOUS.
Journal: JAMA (1888)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
In this issue
Authors: Peter Kirkpatrick, Alexandra Flemming, Charlotte Harrison, Sarah Crunkhorn, Monica Flight, Asher Mullard, Man Tse, Mariam Faruqi, Matthew Smyllie, Isabel Woodman, Lucie Wootton, Catriona Rodwell, Susanne Harris, Vicky Summersby, Patrick Morgan, Kirsten Managing, Judith Shadwell, Simon Fenwick, Natalie Smith, Laura Corns, Ella Lines, Dipti Shah, Marketing Managers, Tim Redding, Nazly De, La Rosa, Peter Collins
Journal: Nature Reviews Drug Discovery (2013)
Differential activation of humoral compensatory mechanisms in distinct stages of portal hypertension
Authors: Lukas Hartl, Mathias Jachs, Christopher Desbalmes, Dunja Schaufler, Ernst Eigenbauer, Rodrig Marculescu, Thomas Szekeres, Rafael Paternostro, Philipp Schwabl, Theresa Bucsics, David JM Bauer, Benedikt Simbrunner, Michael Trauner, Mattias Mandorfer, Thomas Reiberger
Journal: Journal of Hepatology (2020)
Session F: Gynecological Genito-urinary and Elderly Patients' Tumors (Abstract Nos. F1-F48)
Authors: E Burattini, M Palma, F Satta, M Zoffoli, F Todi, T Palma, G Coiro, Y Puce, R Caponetti, A Di, P Di, G Pandoli, F Malorgio, M Vizioli, D Luisi, M Lombardo, R Sorio, G Corona, D Lombardi, M Libra, M Zanetti, A Colussi, S Scalone, G Toffoli, E Campagnutta, Pierfranco Conte, Dionyssios Katsaros, Giuseppe Favalli, Corrado Boni, Giovanni Lenzi, Paolo Zola, Michela Ballardini, Oriana Nanni, Angiolo Gadducci, Dino Amadori, Sergio Pecorelli, C Bumma, M Oletti, I Rigault De La Longrais, A Celano, S Lattuada, E Bertoldo, A Ferrero, T Volpe
Journal: Annals of Oncology (2003)
Dialysis
Authors: M. Christopher W., B. James O.
Journal: BMJ (2014)

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Disruption of TGF-β signaling in T cells accelerates atherosclerosis
Authors: Anna-Karin L. Robertson, Mats Rudling, Xinghua Zhou, Leonid Gorelik, Richard A. Flavell, Göran K. Hansson
Journal: Journal of Clinical Investigation (2003)

Increasing evidence suggests that atherosclerosis is an inflammatory disease promoted by hypercholesterolemia. The role of adaptive immunity has been controversial, however. We hypothesized that proatherogenic T cells are controlled by immunoregulatory cytokines. Among them, TGF-β has been implied in atherosclerosis, but its mechanism of action remains unclear. We crossed atherosclerosis-prone ApoE-knockout mice with transgenic mice carrying a dominant negative TGF-β receptor II in T cells. The ApoE-knockout mice with disrupted TGF-β signaling in T cells exhibited a sixfold increase in aortic lesion surface area, a threefold increase in aortic root lesion size, and a 125-fold increase in aortic IFN-γ mRNA when compared with age-matched ApoE-knockout littermates. When comparing size-matched lesions, those of mice with T cell–specific blockade of TGF-β signaling displayed increased T cells, activated macrophages, and reduced collagen, consistent with a more vulnerable phenotype. Ab's to oxidized LDL, circulating T cell cytokines, and spleen T cell activity were all increased in ApoE-knockout mice with dominant negative TGF-β receptors in T cells. Taken together, these results show that abrogation of TGF-β signaling in T cells increases atherosclerosis and suggest that TGF-β reduces atherosclerosis by dampening T cell activation. Inhibition of T cell activation may therefore represent a strategy for antiatherosclerotic therapy.
Fear.
Journal: JAMA (1896)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
RIO DE JANEIRO
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Corrections
Journal: JAMA (1983)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Kensington Dispensary
Authors: J. H. Bartlett
Journal: BMJ (1866)

The pharmacokinetics of a number of 5,5-dialkyl-substituted barbiturates was studied both in the intact rat and in the isolated perfused rat liver. The half-life or the clearance of a reference compound was used as parameter for the drug metabolic activity of the animal and perfused liver. The rate of elimination of the barbiturates was structure-dependent and seemed to be correlated with the lipophilicity of the compounds which was expressed as the octanol-water and hepatocytes-water partition coefficient. Three features could be distinguished. Firstly, there was a decrease in half-life with the introduction of a larger alkyl side chain. Secondly, substitution of a bromoallyl instead of an allyl group had the same effect and thirdly, a more rapidly eliminated barbiturate could be obtained by the introduction of a methyl group onto the nitrogen of the barbiturate nucleus. The elimination clearance constants relative to the heptabarbital clearance were in the same order of magnitude as those found in man. This result suggests that it is possible to predict the clearance values in man by studying relative values in rats.
Instruction Course Program
Authors: H Dunbar Hoskins, James Ferguson, A Berlin, Susan Day, Craig George, Richard Lewis, John Mccrary, Edward Mclean, Walter Stark, Robert Sergott, Pa Patrick, M Flaharty, Charles Garcia, Richard Ruiz, Michael Bloome, James Karesh, Steven Dresner, Santa Monica, James Vander, Cherry Hill, Jay Duker, Jose Pulido, Patrick O'connor, San Antonio, ; Lanning, B Kline, John Carter, Howard Lieberman, Carol Ruehl, Samuel Salamon, Gerald Zaidman, Ny Gregory, J Louis, J Rowsey, Kenneth Cohen, Chapel Hill, Bradley Fouraker, Sl Louis, Peter Mcdonnell, Los Angeles, San Fujikawa, Donald Fletcher, Kansas City, August Colenbrander, Jerry Shields, Carol Shields, Patrick De Potter, James Kinyoun, ; Thomas, Felix Sabates, King Lee, Nelson Sabates, Kenneth Hoffer, John Shammas
Journal: Ophthalmology (1992)
New Normal in Pertussis Incidence
Journal: JAMA (2015)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Ciguatera fish poisoning in Miami
Authors: D. N. Lawrence
Journal: JAMA (1980)

Ciguatoxic fish constitute a continuing foodborne disease problem in Miami. Information from 129 cases of ciguatera fish poisoning reported to the Dade County (Miami) Department of Public Health during 1974 to 1976 was used for epidemiologic study of the syndrome. The case definition required that both gastrointestinal and paresthetic neurological symptoms be experienced within 36 hours after eating fish. Grouper and snapper were the fish most frequently implicated. Neither methods of storage nor means of preparation seemed to affect fish toxicity. A predominantly late spring and summer seasonality was noted. The true annual incidence of this syndrome in Miami may be ten times the number reported to the health department, suggesting an average annual incidence of at least five cases per 10,000 resident population. Recent advances in ciguatoxin research may lead to much needed assays for toxin detection. (<i>JAMA</i>244:254-258, 1980)
Placement of Elective Skin Incisions
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Therapeutic substitution: usurpation of the physician's prerogative
Journal: JAMA (1987)

<h3>To the Editor.—</h3> It is unfortunate that Dr Ballin's recent editorial on therapeutic substitution<sup>1</sup>implies that organized pharmacy is launching some kind of concerted campaign to usurp the prerogatives of medical practitioners. No organization in American pharmacy, and certainly not the American Pharmaceutical Association, advocates indiscriminate therapeutic substitution by pharmacists. All of the examples cited by Dr Ballin in which pharmacists are taking a more active role in drug therapy share as a feature dialogue and joint decision making by physicians and pharmacists. In both Washington and California, pharmacists act under strict protocols jointly developed by the two professions, and in Florida pharmacists are permitted to dispense only a few drugs in five categories, all of which were selected by a committee on which both pharmacists and physicians are represented. As Dr Ballin observes, pharmacists are much better trained than they were a few years ago, and as a
Myeloid Hyperplasia in the SENCAR Mouse: Differentiation from Granulocytic Leukemia
Authors: Richard E. Long, Gary Knutsen, Merrel Robinson
Journal: Environmental Health Perspectives (1986)

The term myeloid hyperplasia has been used interchangeably with many other terms to describe an increased production of granulocytes, megakaryocytes, and erythrocytes in the spleen and other organs in the mouse. This process is occasionally misdiagnosed as granulocytic leukemia. This paper reviews some of the terms used interchangeably with myeloid hyperplasia and describes criteria that can be used to differentiate myeloid hyperplasia from granulocytic leukemia. Additionally, the results of a study in which myeloid hyperplasia was induced following the formation of skin tumors in SENCAR mice is discussed. In this study, positive correlations were found between skin lesions, the spleen weight, and histologic appearance of the spleen. The liver rarely showed microscopic changes of myeloid hyperplasia unless the spleen weighed at least 1.0% of the body weight.
Radiotherapy plus hyperthermia equals progress against cancer
Authors: M. Korcok
Journal: JAMA (1981)

A number of centers across the country report encouraging results from the use of hyperthermia in conjunction with radiation therapy to manage various types of cancer. Some of the studies reported are still animal studies or phase I or phase II trials and the patient numbers are relatively modest. But radiation oncologists are buoyed by what they see as consistency in the findings. Though several reports presented recently at the meeting of the American Society of Therapeutic Radiologists in Miami Beach cautioned that there is much to learn about the effects of heat on body systems and about the delivery and measurement of heat intensity in tumor tissue, they also emphasized that precise, localized heating combined with radiotherapy can dramatically increase the control of tumor recurrence not only in superficial sites but in some deep-seated ones as well. One such report, by Michael R. Manning, MD, assistant professor of radiology
FREDERICK GRANT BANTING (1891-1941) CODISCOVERER OF INSULIN
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Applications of Gene Arrays in Environmental Toxicology: Fingerprints of Gene Regulation Associated with Cadmium Chloride, Benzo(a)pyrene, and Trichloroethylene
Authors: Matthew Bartosiewicz, Sharron Penn, Alan Buckpitt
Journal: Environmental Health Perspectives (2001)

Toxicity testing of unknown chemicals currently uses a number of short-term bioassays. These tests are costly and time consuming, require large numbers of animals, and generally focus on a single end point. The recent development of DNA arrays provides a potential mechanism for increasing the efficiency of standard toxicity testing through genome-wide assessments of gene regulation. In this study, we used DNA arrays containing 148 genes for xenobiotic metabolizing enzymes, DNA repair enzymes, heat shock proteins, cytokines, and housekeeping genes to examine gene expression patterns in the liver in response to cadmium chloride, benzo(a)pyrene (BaP), and trichloroethylene (TCE). Dose-response studies were carried out in mice for each chemical; each produced a unique pattern of gene induction. As expected, CdCl2 markedly up-regulated metallothionine I and II (5- to 10,000-fold at the highest doses) and several of the heat shock/stress response proteins and early response genes. In contrast, administration of BaP up-regulated only Cyp1a1 and Cyp1a2 genes and produced no significant increases in any of the stress response genes or any of the DNA repair genes present on the array. Likewise, TCE-induced gene induction was highly selective; only Hsp 25 and 86 and Cyp2a were up-regulated at the highest dose tested. Microarray analysis with a highly focused set of genes is capable of discriminating between different classes of toxicants and has potential for differentiating highly noxious versus more subtle toxic agents. These data suggest that use of microarrays to evaluate the potential hazards of unknown chemicals or chemical mixtures must include multiple doses and time points to provide effective assessments of potential toxicity of these substances.
The Process of Diagnosis Including the Method of History-Taking, and Physical Examination of Surgical Cases.
Journal: JAMA (1923)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal