tbuckley/cabot-search huggingface dataset:
Public Says Preserve Medical Research
Journal: JAMA (1995)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Government Services
Journal: JAMA (1925)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Erratum
Journal: BMJ (1926)

DR. J. S. TOWNLEY (Crickhowell) asks how many L6clanche cells would be nieeded to passacuirrentof 5 to 20 milliamperes through a 12 st.mian from thie mastoids to the hauds, anid what such a battery wviti proper resistance wvould cost approximately ?*** Approximately thlirty cells.A resistance would not be wanted, buit a collector switch would be required, so as to be able to switch in (say) at twventy cells and afterwards to thirty.The cells cost 2s.61.each.A collector switch oln the board would have to be specially ma(le, anid 30s.should be allowed for that.A better arrangemlenit would be a self-contained battery of dry cells-generally forty cel:s-ini a box, witil a collector switch all mounted tip togethe.r.This gives a slower anid better regulation, anid is a recognized piece of apparatus in electro-medical cata- loguies.Tiue cost is about £9; this is highier thani the other arraing,emient, but it lhas the advantage of beinig a single unit.CHRONIC ULCERS OF MUCOUS MEMBRANES.DR. C. E. PRATT (13exley hleath) writes, in answer to "A.F.'s" questioni (August 28tlh, p. 407) as to the treatment of chroniic ulcers of mucous membranies, to recommend a course of collosol manganese and small doses of thyroid.Of the former he advises nlxv three times a day in water, -gradually increasing to 1 drachm; of tlhe tlhyroid a tablet of 112 or 1 grain.ASTHIMA AND BRONCHITIS."GENERAL PRACTITIONER " writes in reply to " P.'s " query regar(iitng chroniic astlhma anid bronchitis: I prefer to relieve tile broncDiitic elemenit first with the miixtture recommended, I believe, by Sir R. Douglas Powell: Ammon.chlor.gr.x, Potass.bicarb.gr.xv, Liq.picis aromat.(Bell) 3ss, Ext.glycyrrh.liq.nmxx, Tiniet.cardam.co.5ss, Aq. ad %ss; in water every four lhouirs
Obstetrics and gynecology
Authors: G. R. Huggins
Journal: JAMA (1990)

During the past several years the development of gonadotropin-releasing hormone agonist (GnRH-a) therapy has provided the gynecologist with significant new therapies in infertility and general gynecology. Perhaps 25% to 33% of female infertility is the result of ovulatory failure. The initiating problem may be located in one or multiple foci in the hypothalamic-pituitary-ovarian axis. Since 1971 when gonadotropin-releasing hormone (GnRH) was first isolated, numerous studies have demonstrated its value in diverse regimens designed to overcome ovulatory dysfunction. Gonadotropin-releasing hormone, located primarily in the hypothalamus, is normally released in a pulsatile fashion into the pituitary portal circulation, where it stimulates the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Despite intensive study and widespread availability, the use of GnRH has often proved disappointing in the induction of ovulation for patients with ovulatory dysfunction and for patients undergoing controlled ovarian hyperstimulation for in vitro fertilization/gamete intrafallopian transfer. Leuprolide ([D-Leu<sup>6</sup>, Pro
Pharmacotherapy for Postmenopausal Osteoporosis
Journal: JAMA (2021)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Improved screening for prostate cancer offers challenging new data to cope with high incidence
Authors: P. Gunby
Journal: JAMA (1996)

HARDLY ANYONE mistakenly calls that gland the "prostrate" anymore. Not only is the prostate's name generally being pronounced more accurately, but the discomfort and danger it can pose also are becoming better understood by the public. A possible near end to both the extra "r" in pronunciation and to public ignorance or reluctance to talk about this sex-related gland appears to be the result of the widespread publicity that the prostate is receiving. This is particularly true where adenocarcinoma of the prostate is involved. The increasing amount and diversity of research into causes of this cancer have resulted in more articles on prostatic adenocarcinoma in the medical literature in this decade than ever before. But much more information also is being offered to the public about prostate cancer. Articles are appearing in many largecirculation magazines and newspapers, as well as in more specifically targeted publications such as health newsletters and
Mucin-vesicle interactions in model bile: Evidence for vesicle aggregation and fusion before cholesterol crystal formation*1, *2
Authors: N AFDHAL
Journal: Hepatology (1995)

Nucleation of cholesterol monohydrate crystals from bile is a critical step in the formation of cholesterol gallstones. Measurement of nucleation in model bile systems and the characteristics of the initial nucleus have proven elusive. In this study we have used three separate physical chemical techniques to examine vesicle aggregation and fusion, including dynamic light scattering (DLS), transmission electron microscopy (TEM), and fluorescent biochemical assays. These assays enabled us to quantify the effect of biliary proteins, such as gallbladder mucin, on vesicle fusion and aggregation. In the absence of mucin, fusion is a relatively slow process occurring over 24 hours, whereas physiological concentrations of mucin are able to accelerate almost complete fusion of vesicles within 6 hours. Vesicle fusion and aggregation as characterized by TEM result in the formation of aggregates of multilamellar vesicles and giant fusion bodies associated with a background of mucin. These mucin-vesicle aggregate bodies may represent true nuclei and precede cholesterol monohydrate crystal nucleation. In future studies, these vesicle fusion assays can be used to quantitatively examine the effect of putative pro- and anti-nucleating proteins on the earliest steps of cholesterol crystal nucleation.
Index of Authors
Journal: JNCI Journal of the National Cancer Institute (1967)

Journal Article Index of Authors Get access JNCI: Journal of the National Cancer Institute, Volume 38, Issue 6, June 1967, Pages 985–987, https://doi.org/10.1093/jnci/38.6.985 Published: 01 June 1967 Article history Received: 27 April 1967 Published: 01 June 1967
Salicylates and Reye's syndrome: epidemiologic data as a basis of action
Authors: E. R. Alexander
Journal: JAMA (1982)

Anecdotal observations that what we now know as Reye's syndrome (RS) was associated with ingestion of salicylates preceded the definition of this syndrome.<sup>1</sup>Reye and coworkers<sup>2</sup>first delineated the syndrome of encephalopathy and fatty degeneration of the viscera following a mild viral illness. We now know that RS follows influenza (particularly type B), chickenpox, and other viral illnesses. It occurs with an annual incidence of one to two children per 100,000 persons younger than 18 years. Of this total, 221 to 551 cases were reported per year for the years 1973 through 1981, with a death-to-case ratio of 22% to 42%. After many descriptive studies of RS, a variety of etiologic hypotheses have been entertained, including insecticides and related chemicals, aflatoxins, and salicylates.<sup>3</sup> Case-control epidemiologic studies were initiated in three separate states to investigate many possible associations with RS. The first was by Starko and colleagues<sup>4</sup>
Continuing medical education: the infinite phase of the continuum
Authors: M. E. Johnson
Journal: JAMA (1980)

The sharp differences of opinions that are emerging about the subjects of continuing medical education (CME), recertification, and reregistration of a physician's license may be partially rooted in the differences of opinion concerning what constitutes a continuum of education. Perhaps the dictionary itself is contributing to the misunderstandings.<i>Webster's New Collegiate Dictionary</i>gives as the first definition of the word continuum the following: 1: something absolutely continuous and homogenous of which no distinction of content can be affirmed except by reference to something else (as duration and extension). The advocates of a continuum of education in which the undergraduate, graduate, and CME segments look exactly alike are apparently taking this definition literally. The basic format suggested for each of these three traditional educational periods would contain much formalized learning followed by periodic written examinations, which serve as a short-term disciplinary function and as a long-term gate to allow or prevent
Comparative Physiology and Psychology.
Authors: None L. H. M.
Journal: JAMA (1885)

This new work includes eleven years labor in the fields its title indicates, and contains much original matter. The intention of the author, we judge, is to elaborate a mental science to accord with recent physiological and anatomical research, which has been well done by him. The reasoning is profound and appeals directly to experience. As the author stated in his introductory remarks, the method proposed to examine the mind is an extension of Herbert Spencer's principles, and we believe is in accordance with the views of the majority of modern scientists. We are pleased to notice a number of chemical formulae in the manner in which they are arranged, as for instance, substituting CO<sub>2</sub>which appears on the ninth line from the top of page 10, to denote carbonic dioxide. So, too, regarding H<sub>2</sub>O for sulphur, as it appears in the fourth line from the top
Contents
Authors: L Rivoltini, V Mazzaferro, E Gowans, S Roberts, K Jones, I Dinatale, P Latour, B Chua, E Eriksson, R Chin, S Li, D Wall, R Sparrow, J Moloney, M Loudovaris, R Ffrench, H Prince, D Hart, W Zeng, J Torresi, L Brown, D Jackson, A Foerster, Y Helmy, R Zhu, O Khattar, K Adeyi, I Wong, D Shalev, P.-Y Clark, E Wong, M Heathcote, D Phillips, E Grant, G Renner, N Levy, S Cheng, G Roberts, W Mccaughan, M Sievert, D Weltman, W Crawford, P Rawlinson, J Marks, B Thommes, M Rizkalla, G Yoshihara, R Miraglia, A Luca, L Maruzzelli, M Spada, S Riva, S Caruso, G Maggiore, B Gridelli, J Bosch, D Sebastiani, G Tempesta, L Fattovich, P Castera, M Halfon, F Bourliere, P Noventa, A Angeli, A Saggioro
Journal: Journal of Hepatology (2010)
The Science of Quality Improvement—Reply
Journal: JAMA (2008)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
OVERNUTRITION AND UNDERNUTRITION
Journal: JAMA (1953)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
APPLE News
Authors: Terry M. Therneau, Lewis R. Roberts, Hager A. Ahmed Mohammed, Ju Dong Yang, Nasra H. Giama, Jonggi Choi, Hawa M. Ali, Kristin C. Mara, William S. Harmsen, Russell H. Wiesner, Michael D. Leise, Naoshi Nishida, Satoru Hagiwara, Toshiharu Sakurai, Masatoshi Kudo, Tadaaki Arizumi, Hiroshi Ida, Yoshihiro Sakamoto, Norihiro Kokudo, Yoshikuni Kawaguchi, Keiichi Akita, Guido Torzilli, Masatoshi Kudo, Naoki Morimoto, Norio Isoda, Yoshinari Takaoka, Takuya Hirosawa, Shunji Watanabe, Toshiya Otake, Kozue Murayama, Mamiko Tsukui, Takeshi Fujieda, Natsumi Miyata, Kohei Ono, Shota Yamaguchi, Hironori Yamamoto, Masamitsu Kumon, Druckerei Stückle, Druckerei Stückle
Journal: Liver Cancer (2017)
Recent Contributions to Adolescent Medicine
Authors: J. Roswell Gallagher, Felix P. Heald, Robert P. Masland
Journal: New England Journal of Medicine (1958)

"Did you never hear how the life of man is divided? Twenty years a-growing, twenty years in blossom, twenty years a-stooping, and twenty years declining."1 ABOUT twenty-five years ago we witnessed an expansion of interest in the problems of the aging and the aged, stimulated to a considerable extent by the increase in the number of people living beyond the sixth decade. Similar, but as yet much less widespread, attention is now being given to another age group, — that of people in the process of becoming adults, — or adolescents. Though the reasons for an increased interest in senescence . . .
Lymphatic Removal of Fluids and Particles in the Mammalian Lung
Authors: Lee V. Leak
Journal: Environmental Health Perspectives (1980)

The structure and distribution of pulmonary lymphatics and their permeability to fluids and particulate materials have been investigated in the lungs of rats following fixation by combined intratracheal and vascular perfusion. In such preparations, the lymphatics remain in a distended state, and a close relationship to other structural components of the pulmonary interstitium is maintained. They were identified in regions with an abundant amount of connective tissue, forming an eleborate plexus within the pleura, the interlobular septum, peribronchial and perivascular areas. Recent data have shown that water-soluble molecules and particulate matter are removed from the interstitium along the lymphatic capillary (initial lymphatics) segment. It is distinguished by attenuated endothelial cells with extensively overlapping cell margins which are easily separated. We have studied this segment of the lymphatic vascular system following intratracheal injections of colloidal particles (ferritin and carbon) to determine the structural features responsible for the transport of large molecules and particulate materials across the lymphatic endothelial wall in the lung. The results showed that the tracer particles cross the lymphatic endothelial wall via the clefts of intercellular junctions. While the tracer particles were observed within vesicles, the question of transport across the lymphatic endothelium via plasmalemmal vesicles is still not settled since the number and size of vesicles containing tracer particles also increased with time. Intravascular injected dextran was also localized within the clefts of intercellular junctions and plasmalemmal vesicles. The results obtained with intratracheal and intravascular injected tracer substances are consistent with those observed in lymphatic capillaries for other tissues.
Quantitative Structure-Activity Relationships of Insecticides and Plant Growth Regulators: Comparative Studies toward Understanding the Molecular Mechanism of Action
Authors: Hajime Iwamura, Keiichiro Nishimura, Toshio Fujita
Journal: Environmental Health Perspectives (1985)

Emphasis was put on the comparative quantitative structure-activity approaches to the exploration of action mechanisms of structurally different classes of compounds showing the same type of activity as well as those of the same type of compounds having different actions. Examples were selected from studies performed on insecticides and plant growth regulators, i.e., neurotoxic carbamates, phosphates, pyrethroids and DDT analogs, insect juvenile hormone mimics, and cytokinin agonistic and antagonistic compounds. Similarities and dissimilarities in structures required to elicit activity between compounds classes were revealed in terms of physicochemical parameters, provoking further exploration and evoking insights into the molecular mechanisms of action which may lead to the development of new structures having better qualities.
Exposing Physicians
Authors: Kathryn M Denson
Journal: Annals of Internal Medicine (2009)

On Being a Doctor3 February 2009Exposing PhysiciansKathryn M. Denson, MDKathryn M. Denson, MDFrom the Medical College of Wisconsin, Milwaukee, WI 53295.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-150-3-200902030-00013 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail The edge of the toupee caught my eye as I tipped the patient's head gently forward. I was surprised. The hairpiece looked so real. The edge was rough and upturned slightly, gray in color. I don't think that I would have noticed it if the front edge hadn't been slightly ragged. I was starting to look at the scalp during my physical examination. I ignored the toupee—pretended I didn't see it. I could hear my residency attending's voice in my mind, “Always be thorough, and don't forget to look under the dentures.” I supposed this would extend to the scalp ... Author, Article, and Disclosure InformationAffiliations: From the Medical College of Wisconsin, Milwaukee, WI 53295.Corresponding Author: Kathryn M. Denson, MD, Zablocki Veterans Affairs Medical Center, 5000 West National Avenue, Milwaukee, WI 53214; e-mail, [email protected]edu. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 3 February 2009Volume 150, Issue 3Page: 218KeywordsCognitionDementiaEmotionsFellowshipsGeriatricsMemoryMini mental state examinationPerceptionResidencyRestless legs syndrome ePublished: 3 February 2009 Issue Published: 3 February 2009 Copyright & PermissionsCopyright © 2009 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Found Poem
Authors: Daniel Bosch
Journal: Annals of Internal Medicine (2014)

Ad Libitum1 July 2014Found PoemDaniel BoschDaniel BoschFrom Chicago, IllinoisSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/M14-0064 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail (hospital waiting room)O AlwaysO SometimesO NeverO Does Not ApplyDaniel BoschChicago, Illinois Author, Article, and Disclosure InformationAffiliations: From Chicago, IllinoisCurrent Author Address: Daniel Bosch; e-mail, [email protected]com PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 July 2014Volume 161, Issue 1Page: 72 ePublished: 1 July 2014 Issue Published: 1 July 2014 Copyright & PermissionsCopyright © 2014 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...