tbuckley/cabot-search huggingface dataset:
Surgical and Anticoagulant Therapy of Occlusive Cerebrovascular Disease.
Authors: R. G. Siekert
Journal: Annals of Internal Medicine (1962)

s1 April 1962Surgical and Anticoagulant Therapy of Occlusive Cerebrovascular Disease.R. G. Siekert, M.D., F.A.C.P., J. P. Whisnant, M.D. (Assoc.), C. H. Millikan, M.D., F.A.C.P.R. G. Siekert, M.D., F.A.C.P.Search for more papers by this author, J. P. Whisnant, M.D. (Assoc.)Search for more papers by this author, C. H. Millikan, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-56-4-671_3 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn recent years the use of anticoagulant therapy and surgical therapy has been advocated for certain varieties of occlusive (ischemic) cerebrovascular disease. Some difference exists among the proponents of the various therapies as to the indications of each therapy in various clinical categories. Frequently, one therapy has been used to the exclusion of the other.In general, six categories of patients must be considered in the evaluation of the usefulness of any therapy. There are the three clinical groups: [1] intermittent insufficiency (normal neurologic status); [2] progressing stroke (advancing neurologic deficit); and [3] completed stroke (stable neurologic deficit). Each of... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Rochester, Minn. (CS) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 April 1962Volume 56, Issue 4Page: 671-672KeywordsAnticoagulant therapyCerebrovascular diseasesStroke Issue Published: 1 April 1962 PDF DownloadLoading ...
Benefit of Heparin Plus Aspirin vs Aspirin Alone in Unstable Angina
Authors: Robert P. Blankfield
Journal: JAMA (1996)

<h3>To the Editor.</h3> —The article by Dr Oler et al<sup>1</sup>on unstable angina found a 2.9% absolute reduction for the combined outcome of nonfatal MI or death with heparin and aspirin, accompanied by a 1.5% increase in major bleeding. The authors' conclusion, that "most patients with unstable angina should be treated with both aspirin and heparin," should be accompanied by several caveats. Among the 6 trials included, only 2 were double blinded and these found no treatment differences. As it has been previously established that unblinded randomized trials may be associated with increased effect sizes,<sup>2</sup>the magnitude of the heparin treatment effect may be overestimated. Moreover, the clinical heterogeneity of unstable angina makes the formulation of all encompassing treatment options precarious, as highlighted by the paradoxical result that the trial with the greatest rate of adverse outcomes failed to show a difference between the 2 treatments.<sup>3</sup>This heterogeneity has been
International Symposium on the Immune System: Function and Therapy of Dysfunction
Journal: JNCI Journal of the National Cancer Institute (1978)

Journal Article International Symposium on the Immune System: Function and Therapy of Dysfunction Get access JNCI: Journal of the National Cancer Institute, Volume 60, Issue 5, May 1978, Page 1184, https://doi.org/10.1093/jnci/60.5.1184-a Published: 01 May 1978
An extended study of indomethacin. II. Clinical therapy
Authors: N. O. Rothermich
Journal: JAMA (1966)

A new antirheumatic drug, indomethacin, was evaluated over a long period of observation (42 months maximum). Clinically satisfactory results listed as both good and excellent were obtained in a high percentage of patients with ankylosing spondylitis, gouty polyarthritis, psoriatic arthritis, and other miscellaneous benign (nonfatal) rheumatic diseases. In rheumatoid arthritis, indomethacin produced good and excellent results in a lesser, though appreciable, percentage of cases and may be regarded as another valuable drug to be added to the overall program of therapy in this notably difficult disease. As indicated in the previous report, the experimental nature of this study required that in some cases the dosages be increased to and beyond tolerance. Therefore, therapy in private practice may not yield as high a percentage of favorable results as indicated in this report.
The Great Winds of the Earth
Journal: JAMA (1974)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
INTOXICATION WITH CREOSOTE.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
SÉE ON THE TREATMENT OF ANEURISM
Journal: JAMA (1988)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Health Status of Japanese and Taiwanese after Exposure to Contaminated Rice Oil
Authors: Yoshito Masuda
Journal: Environmental Health Perspectives (1985)

Mass poisonings, called yusho and yu-cheng, occurred in western Japan in 1968 and central Taiwan in 1979, respectively. These occurrences were separately caused by ingestion of rice oils contaminated with polychlorinated biphenyls (PCBs), polychlorinated dibenzofurans (PCDFs) and polychlorinated quaterphenyls. The total intakes of PCBs and PCDFs by the patients were calculated to be, on the average, 633 and 3.4 mg for yusho, respectively, and 973 and 3.84 mg for yu-cheng, respectively, similar amounts of the causal agents being ingested in both instances. Increased eye discharge, pigmentation of nails, skin and mucous membrane, acneform eruptions and feeling of weakness were the most notable symptoms for both the poisonings. The PCB concentrations in the blood of patients were 1-30 ppb for yusho and 3-1156 ppb for yu-cheng five years and one year after the outbreaks, respectively. For the yusho patients, the clinical severity was closely related to the total amount of rice oil consumed and to the blood PCB concentration and the gas chromatographic pattern of blood PCBs.
The Banyan Tree
Journal: JAMA (1969)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Cover
Authors: Sam Seifter
Journal: JAMA (1987)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Intragastric Cooling in Management of Hemorrhage from Upper Gastrointestinal Tract
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
IMMUNITY.CHAPTER XXXI (Concluded).
Journal: JAMA (1905)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Cecal lithiasis secondary to cecal stenosis. Report of a case in an adult
Authors: A. L. Gundersen
Journal: JAMA (1968)

A review of the causes and locations of intestinal stenosis revealed that it rarely is found in the colon and that none has been reported in the cecum below the ileocecal valve. Cecal lithiasis, below a cecal web, occurred in a 54-year-old man. Treatment consisted of linear colotomy and incision of the web, removal of stones, and transverse closure. Formation of stones and the late appearance of symptoms from the poorly drained cecal reservoir were due to the location of the stenosis.
Massachusetts Medical Society
Authors: Charles L. Brennan, George L. Maison, Frank N. Allan
Journal: New England Journal of Medicine (1951)

CHANGE IN THE RESTRICTIONS ON THE REFILL OF PRESCRIPTIONSAdditional Report from the Committee on Pharmaceutical ProblemsOn December 5, 1950, Mr. Oscar R. Ewing, federal security administrator, proposed a new regulation intended to eliminate misunderstandings about the restrictions on the refill of prescriptions.Mr. Ewing's statement implied that the new regulation would relax the restriction on the refill of so-called over-the-counter drugs — those that may be freely sold without prescriptions. There will be no relaxation in regard to "prescription drugs," including those classified as dangerous drugs (for example, barbiturates, sulfa drugs and thyroid tablets), and preparations labeled by . . .
Informed consent for genetic research on stored tissue samples
Authors: E. W. Clayton
Journal: JAMA (1995)

<h3>Objective.</h3> —To develop recommendations for obtaining adequate informed consent in the future when gathering tissue samples that may be used for genetic studies and defining the circumstances under which it is necessary to obtain further consent if tissue samples already in hand are to be used for such research. <h3>Participants.</h3> —Scientists, ethicists, lawyers, and consumers selected by the National Center for Human Genome Research and the Centers for Disease Control and Prevention to represent a wide array of opinions. <h3>Evidence.</h3> —Statutes, regulations, and cases and articles on law and ethics. <h3>Consensus Process.</h3> —Initial workshop, followed by circulation of several drafts of this document with opportunities for comment by workshop participants and others as well as smaller meetings involving participants with widely differing views. <h3>Conclusions.</h3> —Genetic research using stored tissue samples poses an array of benefits and risks to individuals, researchers, and society. As a result, the workshop participants conclude that (1) informed consent is required for all genetic research using linkable samples unless conditions for limitation or waiver are met; (2) informed consent is not required for genetic research using anonymous samples but may be considered if identifiers are to be removed from currently linkable samples; (3) institutional review boards could usefully review all protocols that propose to use samples for genetic research; and (4) further work regarding these issues is warranted. (<i>JAMA</i>. 1995;274:1786-1792)
Cardiovascular monitoring during acute myocardial infarction. New trends
Authors: W. W. Parmley
Journal: JAMA (1974)

EXPERIENCE in coronary care units during the past few years has demonstrated the importance of continuous electrocardiographic monitoring and immediate therapy of ventricular arrhythmias. More recently there has been a greater appreciation of the importance of monitoring hemodynamic events in these acutely ill patients. The ability to make such measurements has been greatly enhanced by the introduction of a new generation of balloon-tip flotation catheters.<sup>1</sup>The principle of their use is that blood flow will propel the inflated balloon at the tip of the catheter through the right side of the heart and into the pulmonary artery, where it can be deflated subsequently. Such catheters can be passed at the bedside (without fluoroscopy) in a high percentage of cases. Placement of the catheter tip in the pulmonary artery allows for the direct measurement of pulmonary artery pressure. Furthermore, when the balloon is reinflated transiently to occlude a branch of
Book Reviews
Journal: Allergy (1982)

Book reviewed in this article: Reisfeld, R. A. &amp; Ferrone, S. (eds.): Current trends in histocompatibility. Nydegger, U. E. (ed.): Immunotherapy. Rees, A. R. &amp; Purcell, H.J. (eds.): Disease and the environment. Dukor, P., Kallós, P., Schlumberger, H. D. &amp; West, G. B. (eds.): Pesudo‐allergic reactions. Ishizaka, K., Kallós, P., Waksman, B. H. &amp; Week, A. L. de (eds.): Regulation of the IgE antibody response. Wendt, H. &amp; Frosch, P. J.: Clinico‐pharmacological models for the assay of topical corticoids. Speer, F.: Handbook of clinical allergy: A practical guide to patient managements.
PREVENTION OF EPIDEMIC CEREBROSPINAL MENINGITIS.
Journal: JAMA (2006)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Leads from the MMWR. Rocky Mountain spotted fever--United States, 1985
Journal: JAMA (1986)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstracts
Journal: Annals of the Rheumatic Diseases (1957)

Investigations were carried out at the Rheumatic Fever Research Institute, Chicago, into the significance of the colour development in the deproteinized "serum blank" on heating with the sulphuric-acetic acid mixture used in the well-known diphenylamine reaction of Dische for the estimation of sialic acid in glycoprotein complexes.This colour is also probably due to sialic acid, and estimation after heating with the sulphuric-acetic acid mixture alone, although less sensitive than the diphenyl- amine method, is simpler [and obviates the "allergic reactions" in many technicians].Indoles, pyrroles, and tryptophan produce colour with this reagent, but are considered to be removed by protein precipitation with hot 5 per cent.trichloracetic acid.The reagent which the authors recommend is one of 5 per cent.sulphuric acid and 95 per cent.glacial acetic acid heated in a boiling water-bath for 30 minutes.The colour is determined spectrophotometrically at 530 my.The supernatant solution remaining after precipitation of the serum protein with hot 5 per cent.trichloracetic acid was dialysed, frozen, and lyophilized, and contained 17 per cent.hexoses, 3 5 per cent.hexosamine, 13 per cent.sialic acid, and 5 -8 per cent.nitrogen.The colour absorption curves obtained after treatment of this material with the sulphuric-acetic acid and diphenyl- amine reagents were practically identical with those obtained with pure sialic acid.Serum from healthy subjects gave an optical density of 0-265±0-019 units.Higher levels were found during the "acute phase" of acute rheumatic fever, tuberculosis, and cancer.Serial determinations were made in comparison with the erythrocyte sedimentation rate (Wintrobe) as an expres- sion of rheumatic activity.The raised sialic acid levels were usually 2 weeks later in returning to normal than the erythrocyte sedimentation rate, and also persisted after the C-reactive protein reaction became negative.Harry Coke.