tbuckley/cabot-search huggingface dataset:
Doctor Joseph Leidy; A Portrait.
Journal: JAMA (1904)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Health Applications of Smokeless Tobacco Use
Journal: JAMA (1986)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Leads from the MMWR. Recommendations for assisting in the prevention of perinatal transmission of HTLV-III/LAV and acquired immunodeficiency syndrome
Journal: JAMA (1986)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Use of a teaching pneumatic otoscope
Authors: D. W. Teele
Journal: JAMA (1979)

<h3>To the Editor.—</h3> A review of the book by Günter Ammon,<i>Psychoanalysis and Psychosomatics</i>(241:1939, 1979), notes that "in 1922 one of Freud's followers, Felix Deutsch, a Viennese psychiatrist, seemed set to unravel the secrets of mind-body interaction when he coined the term psychosomatic." It was, in fact, Johann Christian Heinroth (1773-1843), author of<i>Lehrbuch der Stoerungen des Seelenlebens</i>, who is generally credited with having coined the term "psychosomatic medicine."<sup>1</sup> Heinroth was concerned with mental illness as a disease of the soul, with sin as a cause of disease, and with psychotherapy, classification of mental illness, and the history of these subjects. He first used the term "psychosomatic" in 1818, but psychosomatic medicine as a field of scientific study and clinical evaluation clearly developed most intensively only during the past few decades, having come into special prominence after 1935, the publication date of Dunbar's<sup>2</sup>survey. Ackerknecht<sup>3</sup>comments
International Clinics.
Journal: JAMA (1897)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hospice Effect on Medicare Expenditures
Authors: Diane Campbell, Joanne Lynn, Lisa R. Shugarman
Journal: Annals of Internal Medicine (2004)

Letters7 September 2004Hospice Effect on Medicare ExpendituresDiane Campbell, PhD, Joanne Lynn, MD, MA, MS, and Lisa R. Shugarman, PhDDiane Campbell, PhDFrom Medical Outcomes Research and Evaluation Services, Thetford, VT 05074; Washington Home Center for Palliative Care Studies, Washington, DC 20016; and RAND Corp., Santa Monica, CA 90407.Search for more papers by this author, Joanne Lynn, MD, MA, MSFrom Medical Outcomes Research and Evaluation Services, Thetford, VT 05074; Washington Home Center for Palliative Care Studies, Washington, DC 20016; and RAND Corp., Santa Monica, CA 90407.Search for more papers by this author, and Lisa R. Shugarman, PhDFrom Medical Outcomes Research and Evaluation Services, Thetford, VT 05074; Washington Home Center for Palliative Care Studies, Washington, DC 20016; and RAND Corp., Santa Monica, CA 90407.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-141-5-200409070-00030 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:The letter from Drs. Gozalo, Mor, and Miller appears to raise 2 issues. One concerns potential bias in our hospice effect estimation related to controlling for consistently low service use for 24 months before death. We did test for the effect of this variable and stated that the results persisted among all sensitivity analyses, including “models that do not correct for consistently low Medicare use.”The other issue turns on the effectiveness of propensity scores to control for selection bias, particularly in study samples, such as ours, in which nursing home residents are combined with community dwellers. Our ... Author, Article, and Disclosure InformationAffiliations: From Medical Outcomes Research and Evaluation Services, Thetford, VT 05074; Washington Home Center for Palliative Care Studies, Washington, DC 20016; and RAND Corp., Santa Monica, CA 90407. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoMedicare Program Expenditures Associated with Hospice Use Diane E. Campbell , Joanne Lynn , Tom A. Louis , and Lisa R. Shugarman Hospice Effect on Medicare Expenditures Pedro Gozalo , Vince Mor , and Susan Miller Metrics Cited byDifferences in medicare expenditures during the last 3 years of life 7 September 2004Volume 141, Issue 5Page: 410KeywordsAge groupsForecastingMedicareNursing homesObservational studiesRacial and ethnic issuesSexual identity ePublished: 7 September 2004 Issue Published: 7 September 2004 Copyright & PermissionsCopyright © 2004 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Polygraph. Council on Scientific Affairs
Journal: JAMA (1986)

The American Medical Association (AMA) Council on Scientific Affairs has reviewed the data on the validity and accuracy of polygraphy testing as it is applied today. The use of the control question technique in criminal cases is time honored and has seen much scientific study. It is established that classification of guilty can be made with 75% to 97% accuracy, but the rate of false-positives is often sufficiently high to preclude use of this test as the sole arbiter of guilt or innocence. This does not preclude using the polygraph test in criminal investigations as evidence or as another source of information to guide the investigation with full appreciation of the limitations in its use. Application of the polygraph in personnel screening, although gaining in popularity, has not been adequately validated. The few limited studies that have been performed suggest no greater accuracy for the types of testing done for this purpose than for the control question polygraph testing used in criminal cases. The effect of polygraph testing to deter theft and fraud associated with employment has never been measured, nor has its impact on employee morale and productivity been determined. Much more serious research needs to be done before the polygraph should be generally accepted for this purpose.
Hypertension: some unanswered questions
Authors: W. Burke
Journal: JAMA (1985)

The measurement of a patient's blood pressure is a routine procedure when a person visits a physician or health facility. We carry out this test because elevated blood pressure is an etiologic factor for the development of stroke, coronary heart disease, congestive heart failure, and renal failure. In recent years, many different drugs have become available to reduce blood pressure. Normalization of elevated blood pressure decreases the risk of the various complications, and vigorous therapy for hypertension is recommended by many authorities. Since the condition is common, millions of individuals are labeled as hypertensives and many are given antihypertensive drugs to lower their blood pressure. Our current policies raise many questions. While we define hypertension as a blood pressure of more than 160/90 mm Hg or thereabouts, this definition is arbitrary. The distribution of blood pressure in the normal population is continuous, with no "cutoff" pressure at which a person
Highlights
Journal: JAMA (2013)

CBT and Amitriptyline for Chronic Migraine in Children 2622Treatment of pediatric migraine is challenging and often not evidence based.Powers and colleagues randomly assigned 135 children and adolescents with chronic migraine to receive 10 sessions of cognitive behavioral therapy (CBT) or headache education-in combination with amitriptyline, a common prophylactic medication for migraine-and found that CBT plus amitriptyline was superior to headache education plus amitriptyline in reducing headache days and migraine-related disability.In an Editorial, Connelly discusses challenges to implementation of CBT in the treatment of chronic migraine in children and adolescents.
Release of soluble intercellular adhesion molecule 1 into bile and serum in murine endotoxin shock
Authors: H JAESCHKE
Journal: Hepatology (1996)

Neutrophil-induced liver injury during endotoxemia is dependent on the adhesion molecules Mac-1 (CD11b/CD18) on neutrophils and its counterreceptor on endothelial cells and hepatocytes, intercellular adhesion molecule 1 (ICAM-1). To investigate a potential release of a soluble form of ICAM-1 (sICAM-1), animals received 100 μg/kg Salmonella abortus equi endotoxin alone or in combination with 700 mg/kg galactosamine. In endotoxin-sensitive mice (C3Heb/FeJ), injection of endotoxin did not cause liver injury but induced a time-dependent increase of sICAM-1 in serum (300%) and in bile (615%) without affecting bile flow. In galactosamine/endotoxin-treated animals, which developed liver injury, the increase in both compartments was only 97% and 104%, respectively. In either case, the increase in sICAM-1 concentrations paralleled the enhanced ICAM-1 expression in the liver. The endotoxin-resistant strain (C3H/HeJ) did not show elevated sICAM-1 levels in serum or bile after endotoxin administration. In contrast, the intravenous injection of murine tumor necrosis factor α (TNF-α), interleukin-1α (IL-1α) or IL-1β (13-23 μg/kg) into endotoxin-resistant mice induced a 225% to 364% increase in serum sICAM-1 and a 370% elevation of the biliary efflux of sICAM-1, again independent of changes in bile flow. These data indicate that cytokines are major inducers of sICAM-1 formation during endotoxemia in vivo. The described experimental model can be used to investigate the role of sICAM-1 in the pathophysiology of inflammatory liver disease.
Clumsy children
Authors: D M Hall
Journal: BMJ (1988)

Clumsy childrenClumsiness may be defined as "a deficit in the acquisition of skills requiring fluent coordinated movement, not explicable by general retardation or demonstrable neurological disease."Unfortunately teachers and parents often use the term as a synonym for idleness, untidiness, lack of discipline, or impulsivity, neglecting the essentially motor nature of the concept.'Henderson points out in a recent review that clumsy children do not form an homogeneous group.2The problem may be predominantly with gross motor functions like skipping or with more refined skills such as handwriting.Motor competence is not a single entity.A child might, for instance, play the piano outstandingly but perform poorly at football.Speech is the most sophisticated of all motor skills, and yet many clumsy children have no difficulty with speech.Clumsy children differ widely in intelligence, concentration, reading ability, and temperament.The occasional child with problems in all these areas gives rise to the notion of the "clumsy child syndrome"-an uncoordinated, untidy, lonely, friendless failure.3Although this tragic stereotype is mentioned in many publications, there is no evidence that the clumsy child syndrome is a definable entity.What causes clumsiness?Is it caused by "minimal brain damage"?By definition clumsy children have no formal neurological signs.Most have no history of perinatal events likely to have caused brain damage,4 but prenatal influences on the developing brain may occasionally be responsible.Children born very small for gestational age tend to perform less well than controls on various psychological measures and
Errors in Figure 2B
Journal: JAMA Network Open (2021)

Medical Education With HospitalPerformance and Patient Outcomes," 1 published January 28, 2021, there were errors in the x-axis label and the data markers for regression coefficients and 95% CIs in panel B of Figure 2. The x-axis label should have been "Association between 30-d readmission rate and $1 million more in GME funding, regression coefficient."In addition, the data markers for acute myocardial infarction, heart failure, coronary artery bypass graft, pneumonia, chronic obstructive pulmonary disease, stroke, hip replacement, and hospitalwide were positioned incorrectly.This article has been corrected.
O164 ALL ORAL FIXED-DOSE COMBINATION SOFOSBUVIR/LEDIPASVIR WITH OR WITHOUT RIBAVIRIN FOR 12 OR 24 WEEKS IN TREATMENT-NAIVE GENOTYPE 1 HCV-INFECTED PATIENTS: THE PHASE 3 ION-1 STUDY
Authors: A. Mangia, P. Marcellin, P. Kwo, G.R. Foster, M. Buti, N. Bräu, A. Muir, J.C. Yang, H. Mo, X. Ding, P.S. Pang, W.T. Symonds, J.G. McHutchison, S. Zeuzem, N. Afdhal
Journal: Journal of Hepatology (2014)
Failure to transmit rubella virus vaccine. A close-contact study in adults
Authors: S. B. Halstead
Journal: JAMA (1971)

Attenuated rubella viruses retain the property of pharyngeal shedding and might cause unrestricted secondary infections in susceptible contacts of vaccinees. To test this possibility, Cendehill rubella vaccine was administered to 15 susceptible women whose husbands were without detectable rubella hemagglutination-inhibition (HI) antibody. All women developed antibody after immunization. No male spouses had HI antibody eight weeks after administration of the vaccine to the women, or approximately five weeks after the expected period of pharyngeal virus shedding. Lack of spread of rubella vaccine virus among young married couples with close physical contact is further evidence for the low transmissibility of these viruses.
Calcifediol in chronic renal insufficiency. Skeletal response
Authors: S. L. Teitelbaum
Journal: JAMA (1976)

Quantitative histology of thin, nondecalcified sections was performed on squential bone biopsy specimens from five patients undergoing long-term hemodialysis and treated with calcifediol (25-hydroxycholecalciferol) for periods of three to nine months. With increase of intestinal absorption of calcium and decline of circulating immunoreactive parathyroid hormone and alkaline phosphatase, the bones of each patient exhibited striking histological improvement. The group as a whole showed statistically significant decreases in osteoclast number and in the percentages of osteoid surface covered by active osteoblasts. Marrow fibrosis was either eliminated or strikingly decreased in each patient. Osteoid volume significantly declined in four of five patients. In patients with osteitis fibrosa as the predominant histological lesion, calcifediol therapy resulted in decreased calcification front activity. Increased activity was the result when osteomalacia predominated. (<i>JAMA</i>235:164-167, 1976)
Locomotor Ataxia Has No Relation With Syphilis.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 4635: Newly established mouse oral carcinoma cell lines and their syngeneic tumorigenesis models
Authors: Yi-Fen Chen, Chung-Ji Liu, Shou-Yen Kao, Shu-Chun Lin, Kuo-Wei Chang
Journal: Cancer Research (2019)

Abstract Oral squamous cell carcinoma (OSCC) is one of the most prevalent malignancies worldwide. Despite the advances in diagnosis and treatment, the survival of OSCC remains to be improved. miR-211 is an oncogenic microRNA frequently disrupted in human OSCC and its high expression is a determinant of patient’s poor survival. Herein, we established four murine OSCC cell lines, designated MOC-L1 - MOC-L4 from the tongue tumor tissues induced by 4-nitroquinoline 1-oxide in K14-EGFP-miR-211 transgenic mice. All cell lines appear green fluorescence and express epithelial markers. The gene expression profiles among cell lines are complex and diverse, while MOC-L1 - MOC-L3 cells carry missense mutations in p53 gene. MOC-L1 exhibits tremendous epithelial-mesenchymal transition and the associated aggressive characteristics. On the contrary, MOC-L4 displays the least invasiveness. Both MOC-L1 and MOC-L2 are clonogenic in vitro and tumorigenic when implemented into dermis or tongue in syngeneic recipients. But, only MOC-L1 exhibits high potential for local regional and distal metastasis. Since the expression of miR-196b in MOC-L1 xenografts drastically decreased upon cisplatin treatment, targeting of miR-196b might facilitate tumor abrogation. As these cell lines originate from the C57BL/6 mouse, which is the strain most suitable for transgenic engineering, to approach the interplay of these OSCC cells with other type of genetically modified cells in immune-competent mice would bestow profound insight on OSCC pathogenesis. Note: This abstract was not presented at the meeting. Citation Format: Yi-Fen Chen, Chung-Ji Liu, Shou-Yen Kao, Shu-Chun Lin, Kuo-Wei Chang. Newly established mouse oral carcinoma cell lines and their syngeneic tumorigenesis models [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 4635.
Incorrect Definition and Incomplete Study Group Name
Authors: Robert Truog, Glenn Cohen, Mark Rockoff
Journal: JAMA (2014)

the report 1 should be read as completely prohibiting the use of lethal injection as a method of execution in the United States.The message of our Viewpoint was that there is solid and irrefutable consensus on this issue.The Code of Ethics of the American Medical Association and similar codes endorsed by the professional societies of nurses, emergency medical technicians, and health care workers at correctional facilities all unequivocally prohibit the participation of their members in executions, and to our knowledge, no code of ethics of any health care organization in the world condones this involvement.White, perhaps unintentionally, seems to call this consensus into question by pointing out that individual health care practitioners may hold different views, but this is irrelevant to the question of whether there is sufficient consensus within the profession as a whole.In every profession there are practitioners who may disagree with the ethical standards of the profession.There are myriad lawyers who would disagree with many rules established by state bar associations relating to legal ethics.Individual members of any profession are free to use their disagreement to help convince their governing bodies to change their policy.To our knowledge, no such efforts to amend the American Medical Association's Code of Ethics have ever been attempted, much less succeeded.As such, individual disagreements do nothing to call the professional consensus into question.We believe that The Constitution Project's recommendation is a de facto call for the prohibition of lethal injection as a method of capital punishment in the United States, and we encourage the authors to amend the report 1 accordingly.