tbuckley/cabot-search huggingface dataset:
Diagnostic radiology
Authors: H. G. Jacobson
Journal: JAMA (1980)

In the past several years, advances in diagnostic radiology have added new dimensions to this discipline. In the main, they involve computerized tomography (CT), ultrasonography, radionuclide scanning (all either completely or relatively noninvasive), and interventional radiology, eg, angioplasty. The number and scope of these innovative developments, leading to significant improvement in diagnostic accuracy and, therefore, in patient care, transcend the availability of space in this presentation. Thus, a brief discussion of the more important developments and their clinical applications follows. <h3>CT of the Head and Spine</h3> Computerized tomographic scanning continues to make significant strides technically, particularly with innovative modifications of software. Through improved handling and digitizing of the accumulated data, CT scans and roentgenograms of the skull and spine may be obtained simultaneously in cases of trauma to these areas, without moving the patient. The cursor then may be used to identify the segments to be scanned, increasing accuracy, reducing
Levodopa
Authors: Fletcher McDowell
Journal: JAMA (1970)

<h3>To the Editor.—</h3> It is certainly true that patients with Parkinson's disease whose mobility has been restored with treatment may retain some postural instability and should be cautioned about the potential risks of greater physical activity. However, we believe that the value of increased mobility far outweighs the risk of fracture or cardiovascular failure. A significant number of mental side effects are clearly related to the ingestion of levodopa. Other mental reactions seem to be related more clearly to other phenomenon including the age of the patient, the severity of Parkinson's disease, the concomitant use of other medications, and the degree of dementia. In our series those patients with dementia or severe Parkinson's disease and those in the older age group are most likely to develop mentation disturbances on levodopa. It is a generally accepted observation that patients with advanced generalized brain disease are quite susceptible to the development of
Encephalomyelitis Induced by a White Matter Fraction
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
MAPHY and the two arms of HAPPHY
Authors: I. Holme
Journal: JAMA (1989)

<h3>To the Editor.—</h3> <i>JAMA</i>recently published comments on the Metoprolol Atherosclerosis Prevention in Hypertensives (MAPHY) Study, together with a response from the authors.<sup>1</sup>I have some additional remarks. Although the Heart Attack Primary Prevention in Hypertension (HAPPHY) and MAPHY trials are judged as different by the Steering Committee of the HAPPHY trial, the MAPHY trial cannot be interpreted independently of the HAPPHY trial findings because all patients in the MAPHY Study are in the HAPPHY trial. Therefore, the meta-analysis presented by Staessen et al cannot be used for comparison of the MAPHY Study with previous trials.<sup>1</sup>The only valid way the comparison could be done would be to make a meta-analysis of the Medical Research Council trial and the International Prospective Primary Prevention Study in Hypertension and the atenolol part of the HAPPHY trial. The Steering Committee of the HAPPHY trial, therefore, should publish the results in the
Plasma renin activity and levodopa in Parkinson's disease
Authors: A. M. Michelakis
Journal: JAMA (1970)

The effect of posture and levodopa therapy on plasma renin activity (PRA) was studied in patients with Parkinson's disease. The PRA was measured with the patient supine and upright before and during levodopa administration. Prior to therapy the mean values with the patients supine and upright were significantly lower than those of normal subjects. While they were receiving levodopa, the mean PRA when the patients were supine remained low while the mean value when the patients were upright became normal. There was an exaggerated response of PRA to upright posture with levodopa therapy. Possible relationship of these findings to the underlying mechanisms of Parkinson's disease and its treatment are discussed.
A Plea for Public Health in Villages.
Journal: JAMA (1892)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Isolated antibody to hepatitis B core antigen and the immune response to hepatitis B vaccination
Authors: D. R. Howell
Journal: JAMA (1988)

<h3>In Reply.—</h3> The letters of Drs Lipinski and Hodgson emphasize the point that many characteristics of indoor air are modified by mechanical ventilation systems. They suggest several specific components of indoor air as potential determinants of the health effects observed in our study. Since our report was based on routinely gathered surveillance data, we do not have information regarding the physical characteristics of the air inside the modern or old barracks during the study period. We recognize the practical significance of defining relationships of specific physical characteristics of indoor air with infectious and other health risks. In this regard, the letters emphasize an important point: since many characteristics of indoor air are affected by mechanical ventilation, studies of the health effects of specific components of indoor air must account for the potentially confounding effects of physical characteristics that concurrently vary. Until such technically difficult studies are done, however, attempts to
Lessons in Hypnotism and the Use of Suggestion, Based Upon the Neuron Motility Hypothesis.
Journal: JAMA (1898)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
CORRECTION
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Oxazepam poisoning in a child
Authors: P. M. Shimkin
Journal: JAMA (1966)

OXAZEPAM (Serax) is a recently introduced drug with pharmacologic and therapeutic properties similar to other members of the benzodiazepine group, eg, chlordiazepoxide hydrochloride (Librium), and diazepam (Valium).<sup>1,2</sup>Troublesome side effects of the earlier compounds have included ataxia, lethargy, drowsiness, paradoxical irritability, nausea, headache, vertigo, decreased libido, enuresis, edema, skin rash, physical dependence, and agranulocytosis. Most frequently observed have been drowsiness and ataxia, especially in the aged; agranulocytosis has been rare.<sup>3</sup>Oxazepam has been reported to produce lower incidence of these side effects, especially ataxia, at comparable doses.<sup>4</sup>Reports of overdosage as yet are few. <h3>Report of a Case</h3> A 2-year-old, 28-lb (12.8-kg), Negro girl was admitted to the hospital 18 hours after she had been fed six 15-mg oxazepam capsules by her 4-year-old sister. Three hours after ingestion, at bedtime, she fell out of bed twice before going to sleep. Twice thereafter she awoke screaming and terrified.
BRONCHOPULMONARY ACTINOMYCOSIS
Authors: E B KAY
Journal: Annals of Internal Medicine (1947)

Article1 April 1947BRONCHOPULMONARY ACTINOMYCOSISEARLE B. KAY, M.D.EARLE B. KAY, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-26-4-581 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe presence of actinomyces in chronic bronchopulmonary infections is more common than it is generally considered to be. Interest in this subject was stimulated following isolation of the ray fungus in two patients with pulmonary suppuration. These patients required pulmonary resection in combination with chemotherapy to obtain cures.1Since then careful search for this organism has been made in similar patients. During the six-month period from May to November 1945, 240 patients were treated for chronic bronchopulmonary infections. Of these, 109 patients hadActinomyces israeliisolated (by direct examination and culture) from the sputum, and 65 from bronchoscopic specimens. The...Bibliography1. KAY EB: Pulmonary actinomycosis. Its treatment by pulmonary resection in conjunction with chemotherapy. A report of two cases. Awaiting publication, Annals of Surgery. Google Scholar2. KAYMEADE EBRH: Penicillin in the treatment of chronic infections of the lungs and bronchi, Jr. Am. Med. Assoc., 1945, cxxix, 200-204. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Cleveland, Ohio*Received for publication July 5, 1946.Section of Thoracic Surgery, Kennedy General Hospital, Memphis, Tennessee. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAbdominal actinomycosis case report and review of antibiotic treatmentThe Immunocompromised HostActinomicosis toracica. A proposito de un casoPulmonary actinomycosis in childrenInfections Due to Non-Clostridial AnaerobesPulmonary actinomycosisGutartige Primärtumoren der Bronchien und LungenActinomycosisActinomycosisPulmonary Actinomycosis Treated By Lung ResectionAktinomykoseAktinomykosePULMONARY ACTINOMYCOSIS OF PSEUDOTUMORAL FORMDie AktinomykosePrevalence of Actinomyces israelii, A. naeslundii, Bacterionema matruchotii, and Candida albicans in Selected Areas of the Oral Cavity and SalivaActinomycosis and nocardiosisORAL STRAINS OF ACTINOMYCESActinomycosis and nocardiosisENDOBRONCHIAL LESIONS IN PULMONARY BLASTOMYCOSISCandida (Monilia) Infection of the Respiratory TractACTINOMYCES IN PUTRID EMPYEMA 1 April 1947Volume 26, Issue 4Page: 581-593KeywordsActinomycesActinomycetales InfectionsActinomycosisChemotherapyCombination chemotherapySputumThoracic surgery ePublished: 1 December 2008 Issue Published: 1 April 1947 PDF downloadLoading ...
An FHL1-containing complex within the cardiomyocyte sarcomere mediates hypertrophic biomechanical stress responses in mice
Authors: Farah Sheikh, Anna Raskin, Pao-Hsien Chu, Stephan Lange, Andrea A. Domenighetti, Ming Zheng, Xingqun Liang, Tong Zhang, Toshitaka Yajima, Yusu Gu, Nancy D. Dalton, Sushil K. Mahata, Gerald W. Dorn, Joan Heller Brown, Kirk L. Peterson, Jeffrey H. Omens, Andrew D. McCulloch, Ju Chen
Journal: Journal of Clinical Investigation (2012)
Maternitas.
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Cost-Effectiveness of Tolvaptan in Autosomal Dominant Polycystic Kidney Disease
Authors: Kevin F. Erickson, Glenn M. Chertow, Jeremy D. Goldhaber-Fiebert
Journal: Annals of Internal Medicine (2014)

Letters21 January 2014Cost-Effectiveness of Tolvaptan in Autosomal Dominant Polycystic Kidney DiseaseKevin F. Erickson, MD, MS, Glenn M. Chertow, MD, MPH, and Jeremy D. Goldhaber-Fiebert, PhDKevin F. Erickson, MD, MSFrom Stanford University, Stanford, California.Search for more papers by this author, Glenn M. Chertow, MD, MPHFrom Stanford University, Stanford, California.Search for more papers by this author, and Jeremy D. Goldhaber-Fiebert, PhDFrom Stanford University, Stanford, California.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/L14-5001-7 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:We agree with Drs. Lineen and Naimark that the eGFR is an imperfect surrogate for the actual GFR and that decreases in the GFR are not identical to those in the eGFR. The treatment benefit that the TEMPO trial investigators describe may also seem greater when assessed using the eGFR instead of the true GFR, although measuring the latter would have been challenging given the relative large sample size and dispersed geography described in this trial.The eGFR necessarily introduces regression error. Ideally, we could relate our model inputs (for example, mortality rates, health-related quality of life, and ...Reference1. Campbell EG, Pham-Kanter G, Vogeli C, Iezzoni LI. Physician acquiescence to patient demands for brand-name drugs: results of a national survey of physicians [Letter]. JAMA Intern Med. 2013;173:237-9. [PMID: 23303297] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Stanford University, Stanford, California.Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M13-0381. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoCost-Effectiveness of Tolvaptan in Autosomal Dominant Polycystic Kidney Disease Kevin F. Erickson , Glenn M. Chertow , and Jeremy D. Goldhaber-Fiebert Cost-Effectiveness of Tolvaptan in Autosomal Dominant Polycystic Kidney Disease James Lineen , David M.J. Naimark , and Cost-Effectiveness of Tolvaptan in Autosomal Dominant Polycystic Kidney Disease Christopher M. Blanchette , Benjamin Gutierrez , and Keith Friend Cost-Effectiveness of Tolvaptan in Autosomal Dominant Polycystic Kidney Disease James Lineen , David M.J. Naimark , and Cost-Effectiveness of Tolvaptan in Autosomal Dominant Polycystic Kidney Disease Christopher M. Blanchette , Benjamin Gutierrez , and Keith Friend Metrics 21 January 2014Volume 160, Issue 2Page: 143KeywordsHyponatremiaKidneysLongitudinal studiesPolycystic kidney diseaseQuality of lifeRenal analysisRenal failureStatins ePublished: 21 January 2014 Issue Published: 21 January 2014 CopyrightCopyright © 2014 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...
Life-Threatening Infection
Authors: Grant O. Westenfelder
Journal: JAMA (1969)

When a patient with bacterial meningitis, bacterial endocarditis, or staphylococcal septicemia is suspected or proved to have severe penicillin allergy, treatment with an antimicrobial agent other than penicillin or one of its semisynthetic analogues may be warranted. Chloramphenicol sodium succinate can be substituted for a penicillin in the treatment of pneumococcal, meningococcic, or<i>Hemophilus influenzae</i>meningitis. Vancomycin hydrochloride can be prescribed as an alternate drug for treatment of enterococcal endocarditis. Vancomycin or cephalothin sodium is recommended for bacterial endocarditis caused by penicillin-susceptible streptococci or for staphylococcal septicemia. Substitutions for a penicillin should be made only if life-threatening penicillin hypersensitivity clearly is present, or as initial therapy in an emergency until time allows allergy study in a patient suspected of being penicillin-sensitive. Tube dilution susceptibility studies and in vitro tests indicatng adequate blood or cerebrospinal fluid antimicrobial activity are required for optimal management.
Some Historical Aspects of N-Aryl Carcinogens and Their Metabolic Activation
Authors: James A. Miller, Elizabeth C. Miller
Journal: Environmental Health Perspectives (1983)

This limited review of the early studies on the activation of the N-aryl carcinogens was written to provide a background for the current research to be presented at this conference on carcinogenesis by N-aryl compounds. Since the work of the past 10 years is too recent to be judged in a historical sense and because those data are much better known by current investigators, this review is generally limited to data up to 1972.
TO PREVENT SELF-ADVERTISING.
Journal: JAMA (1904)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal