tbuckley/cabot-search huggingface dataset:
From the Assistant Secretary for Health
Authors: J. O. Mason
Journal: JAMA (1989)

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From the Food and Drug Administration
Authors: S. L. Nightingale
Journal: JAMA (1992)

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Spinal Cord Injuries: Comprehensive Management and Research
Authors: Oscar Sugar
Journal: JAMA (1977)

The new edition of this comprehensive treatise continues to be an outstanding book written by the man who instigated the formation of centers devoted to the care of para- and quadriplegic patients. These have spread from the original center at Stokes-Mandeville, England, to centers in all continents. At their best, they provide not only for the medical and surgical care of the patients, but also for help in emotional, educational, occupational, recreational, and social aspects of these tragic patients. All these aspects are dealt with in detail by Sir Ludwig. There is a new chapter, "Spinal Cord Ischaemia—Animal Experiments," which really deals with the current research on injuries of the spinal cord in animals, but which fails to mention the use of corticosteroids. Up-to-date material has been added on spinal shock, classification of injuries, deep vein thrombosis, respiratory and renal complications, and legal aspects of spine injuries. Electric detrusor stimulation
CORRECTION
Authors: Georgios Filippou, Bruno Frediani, Adriana Gallo, Luana Menza, Paolo Falsetti, Fabio Baldi, Caterina Acciai, Sauro Lorenzini, Mauro Galeazzi, Roberto Marcolongo
Journal: Annals of the Rheumatic Diseases (2007)

Of the 14 patients classified by ultrasonography as affected with chondrocalcinosis, 13 presented with CPPD crystals in synovial liquid, whereas 2 of the 29 patients of the control group were positive for CPPD crystals at microscopic analysis (table 1).Therefore, ultrasonography demonstrated a high specificity (equal to 96.4%) and good sensitivity (equal to 86.7%), with a positive predictive value of 92% and a negative predictive value of 93%.Considering that CPPD crystals could be found in synovial fluid even when characteristic calcifications are not found in joint tissues by traditional radiology, 5 6 a sensitivity of 86.7% must be an excellent result.The important data of this study is, however, the high specificity of ultrasonography (96%) in identifying CPPD calcifications.Other studies have been carried out on the utility of ultrasonography in knee chondrocalcinosis, 7 8 but this is the only study that has used the presence of CPPD crystals in synovial liquid as a gold standard.The objective of this study was to evaluate the capacity of ultrasonography to offer a diagnosis, by identifying CPPD calcifications.For this purpose, microscopic synovial fluid analysis, the most widely used examination for the diagnosis of CPPD crystal deposition disease, was used as the gold standard.Therefore, ultrasonography, as opposed to traditional radiology (ionizing radiation) and to magnetic resonance imaging (still conflicting data), 9 10 is the only innocuous examination currently available to the physician that is able to identify CPPD crystal deposits.Considering that CPPD crystal deposition disease frequently has a subclinical course and the patient does not always reach the surgery in an acute stage, it is important for the physician to have a tool at his disposal that permits a diagnosis even in the absence of joint effusion.Moreover, the possibility that ultrasonography can be carried out rapidly during a rheumatology examination places it as a prime tool of diagnostic practice when there is suspected CPPD arthropathy.
Efficacy Analysis of Immune Globulin Subcutaneous (Human), 10% (IGSC) Administered Intravenously or Subcutaneously in Subjects with Primary Immunodeficiency Diseases (PIDD)
Authors: R.I. Schiff, R.L. Wasserman, I. Melamed, M. Stein, W. Engl, H. Leibl, D. Gelmont, W.J. Grossman
Journal: Journal of Allergy and Clinical Immunology (2011)
Saphenous vein bypass surgery for impending myocardial infarction. Critical evaluation and current concepts
Authors: B. L. Segal
Journal: JAMA (1973)

Seventeen patients considered to have impending myocardial infarctions were subjected to saphenous vein bypass operation. Each patient had experienced recurrent angina pectoris with electrocardiographic changes of transient ischemia, but no infarction and no enzyme abnormalities. Paroxysmal ventricular tachycardia had occurred in seven patients, and ventricular fibrillation and cardiac arrest in two more. Two patients received triple grafts, 12 received double grafts, and three received only one graft. Three died and three experienced acute myocardial infarctions during operation. Follow-up study revealed that angina pectoris was absent in all patients except one; 11 patients returned to full-time employment, and no arrhythmias recurred. Patency of graft was noted in 85%, or 28 of 35 grafts. The operation may be advised for patients with impending myocardial infarction, as well as for those with life-threatening arrhythmias unresponsive to antiarrhythmic agents.
Archives of Ophthalmology, Chicago
Journal: JAMA (1965)

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Marriages
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Contribution of the Portuguese Laboratory Network for the Diagnosis of Influenza A(H1N1)pdm09 Infection during the 2009/10 and 2010/11 influenza seasons
Authors: Collective Portuguese Laboratory Network for t
Journal: Eurosurveillance (2012)

This article describes the data obtained by the Portuguese Laboratory Network, reactivated following the World Health Organization declaration of the 2009 influenza pandemic, on the diagnoses of influenza A(H1N1)pdm09 infection during the pandemic (2009/10) and post-pandemic (2010/11) influenza seasons. The laboratories analysed and reported cases of influenza-like illness (ILI) and severe acute respiratory infection (SARI) to the National Influenza Reference Laboratory, which performed more detailed antigenic and genetic characterisation of the virus isolates. In 2009/10, a total of 62,089 ILI cases, distributed in two peaks, were analysed, 25,985 of which were positive for influenza A(H1N1)pdm09. Children aged 5-14 years were the most affected. Viruses were both antigenically and genetically similar to the pandemic strain A/California/7/2009, included in the 2009/10 pandemic vaccine. During the post-pandemic season, 1,496 ILI cases were tested for influenza A(H1N1)pdm09, 572 of which were positive. Infection was mainly diagnosed in adolescent and adults. Although the 2010/11 viruses remained antigenically similar to A/California/7/2009, increased genetic variation was observed. During the two seasons, two viruses with the neuraminidase H275Y amino acid substitution, associated with oseltamivir resistance, were detected. The Laboratory Network made an important contribution to the description of the influenza activity in the two seasons. .
Nouveau traité de médecine et de thérapeutique.
Journal: JAMA (1924)

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Role of endoscopy in primary sclerosing cholangitis: European Society of Gastrointestinal Endoscopy (ESGE) and European Association for the Study of the Liver (EASL) Clinical Guideline
Authors: Lars Aabakken, Tom H. Karlsen, Jörg Albert, Marianna Arvanitakis, Olivier Chazouilleres, Jean-Marc Dumonceau, Martti Färkkilä, Peter Fickert, Gideon M. Hirschfield, Andrea Laghi, Marco Marzioni, Michael Fernandez, Stephen P. Pereira, Jürgen Pohl, Jan-Werner Poley, Cyriel Y. Ponsioen, Christoph Schramm, Fredrik Swahn, Andrea Tringali, Cesare Hassan
Journal: Journal of Hepatology (2017)
Radiology, Detroit
Journal: JAMA (1964)

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BEHRING'S RECENT WORK ON TUBERCULOSIS.
Journal: JAMA (1902)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Relative Potency of Xenobiotic Estrogens in an Acute in Vivo Mammalian Assay
Authors: S. R. Milligan, A. V. Balasubramanian, J. C. Kalita
Journal: Environmental Health Perspectives (1998)

The in vivo effects of xenoestrogens are of interest in relation to their potential health risks and/or beneficial effects on humans and animals. However, the apparent in vivo potency of the examined response can be confounded by a short half-life, and the metabolism of estrogens is very dependent on the nature of conversion and/or inactivation. To minimize such variables, we examined the estrogenic potency of a range of xenoestrogens in an acute in vivo assay--the stimulation of increased uterine vascular permeability in ovariectomized mice 4 hr after subcutaneous administration. While estradiol (E 2 ) and estriol (E 3 ; a relatively weak natural estrogen) readily induced vascular responses [median effective dose (ED 50 ) <10 -9 mol], much higher amounts of xenoestrogens were required. Bisphenol A was about 10,000-fold less potent than E 2 and E 3 , and octylphenol and nonylphenol were about 100,000-fold less potent; dioctyl phthalate, benzyl butyl phthalate, dibutyl phthalate, and trichlorinated biphenol produced no effect. Coumestrol was the most active phytoestrogen, with an ED 50 between 10 -6 and 10 -7 mol; genistein was about 10-fold less potent than coumestrol, and neither daidzein nor formononetin produced any marked effect, even at doses up to 10 -5 mol. All increases in vascular permeability could be blocked by the pure antiestrogen ICI 182,780. There was no evidence that any of the compounds could act as an antiestrogen in this assay or that they could exert synergistic effects in combination. These results indicate that even short-term exposure to most of the xenobiotic estrogens can induce typical estrogenic effects in vivo , but their estrogenic potency is very weak even when assessed in an acute response.
Prognostic role of early interim [18F] fluoro-deoxy-glucose positron emission tomography in patients with advanced seminoma undergoing standard treatment.
Authors: Daniele Raggi, Marco Bandini, Patrizia Giannatempo, Elena Farè, Laura Marandino, Maurizio Colecchia, Barbara Padovano, Gianluca Serafini, Alessandra Alessi, Andrea Necchi
Journal: Journal of Clinical Oncology (2020)

5055 Background: In patients (pts) with advanced seminoma, efforts are underway to tailor a risk-adapted treatment strategy to the individual pt. Our main objective was to prospectively determine the prognostic value of [18F]fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT2) after two cycles of bleomycin, etoposide and cisplatin (BEP) or EP chemotherapy under standardized treatment and PET evaluation criteria. Methods: Pts with advanced-stage seminoma were treated with BEP or EP according to guidelines. PET/CT examinations were performed at baseline, after two cycles in all pts and after chemotherapy at physician’s choice. PET/CT response was qualitatively evaluated by two independent nuclear medicine physicians. Contrast-enhanced CT scans were also performed according to the guidelines (at baseline, after treatment, during follow-up). The primary endpoint was the relapse-free survival (RFS). Results: From 01/2009 to 01/2017, 75 consecutive pts were enrolled, of whom 70 were evaluable. The clinical stage was IIA-B and IIC-III in 40% and 60% of the pts, respectively. Eight pts (11.4%) received consolidation radiotherapy. By local assessment, 46 PET/CT2 scans (65.7%) were reported as negative, and 46% of these pts presented with stage IIC-III. The median follow-up was 79 months. Five-year RFS of PET/CT2-positive pts was 75% (95%CI: 60-95%) compared with 97.8% (95%CI: 93.7-100%) of PET/CT2-negative pts (p = .002). This significant improvement in RFS was maintained when analyzing only pts with clinical stage IIC-III (p = 0.04) and by excluding those who received consolidation RT (p = 0.02). An increasing linear association was found between the maximum diameter of retroperitoneal lymph nodes and the rate of PET/CT2+. In univariable Cox regression analyses, PET/CT2+ (HR: 12.9, 95%CI: 1.5-106.9, p = 0.02) and elevated HCG levels (HR: 6.3, 95%CI: 1.2-32.3, p = 0.03) were significantly associated with RFS, whereas IGCCCG risk group was not (p = 0.1). PET/CT2 result was also associated with the tumor shrinkage post-BEP (p = 0.009), whereas complete response at CT did not predict the RFS (p = 0.3). Conclusions: No residual FDG-uptake after 2 cycles of conventional chemotherapy is prognostic in advanced seminoma, may outperform the utility of standard prognostic risk groups and may be more accurate to predict the RFS compared to standard response criteria. Benchmark RFS estimates for the design of the next clinical trials of chemotherapy de-escalation are offered.
Collaboration.
Journal: BMJ (1973)

BRITISH mEDICAL JouRNAL 21 JuLy 1973 1 adrenal haemorrhage is diagnosed it is important to ensure it is not part of a more general disease, the most important part of which is thrombosis of a renal vein, the inferior vea cava, or mesenteric veins.All these lesions have much more serious sequelae and are the commonest causes of death when children succumb with gross adrenal haemorrhages.Massive adrenal haemorrhage in newborn babies needs to be recognized for what it is, but the treatment of the child's general state is of paramount importance, and the mass can be left to look after itself.
Masthead
Authors: Philip Aisen, York Bronx, North Sawkat Anwer, Gilbert Grafton, Maryland Bethesda, St Bacon, William Louis, Margaret Balistreri, Newcastle-Upon-Tyne Bassendine, D Montgomery Bissell, San Francisco, Gunter Blobel, New York, Henry Bodenheimer, Jaime Bosch, Raymond Burk, Susan Burwen, David Carr-Locke, James Darnell, York Nicholas, Roger Davidson, Anna Davis, Maryland Diehl, Jeffrey Friedman, Scott Friedman, Hans Fromm, D Washington, Roberto Govindarajan, West Groszmann, Philip Haven, Virginia Richmond, Murray Heimberg, Jay Hoofnagle, P Steven, Maryland James, P Dean, Atlanta Jones, Georgia Jones, Maryland Kaplowitz, Los Angeles, Michael California, Africa South, Douglas Labrecque, Charles Lieber, Anna Lok, Hong Kong, Jurgen Ludwig, James Malter, Jay Marks
Journal: Hepatology (1992)
Editorial Board
Authors: Donald Leung, Stanley Szefler, Colo Associate, Cezmi Akdis, Davos Switzerland, Andrea Apter, Pedro Philadelphia, Chicago Avila, Joshua Boyce, Robert Bush, Fred Finkelman, Cincinnati Ohio, Dennis Ledford, Tampa Fla, Deborah Meyers, Luigi Notarangelo, David Peden, Chapel Hill, Harald Renz, Marburg Germany, Marc Rothenberg, Hirohisa Saito, William Shearer, Scott Sicherer, New York, Erika Von Mutius, Germany Munich, Vernon Statistics Editor, Hershey Chinchilli, Gordon Bloomberg, St Louis, Larry Borish, Angela Haczku, Jordan Orange, Darryl Zeldin, Leonard Bacharier, Sten Dreborg
Journal: Journal of Allergy and Clinical Immunology (2013)