tbuckley/cabot-search huggingface dataset:
ASPIRATING DISSECTOR FOR TONSIL SURGERY
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A college develops.
Journal: BMJ (1978)

and the continuing maintenance study organised by the South- western Oncology Group5 has an immunotherapy feature to it.One final point of interest in these two reports is that only one case of acute myeloid leukaemia was noted in over 500 patients, occurring after a clinical remission of 40 months.More aggressive chemotherapy might have been expected to incur a wake of second malignancies.Perhaps these will yet emerge-when more clinicians shake off their pessimism and address themselves to the renewed therapeutic challenge of myeloma.
Abstract 1105: Cisplatin treatment alters the preference of melanoma metastasis to liver associated with Ly6G positive cells
Authors: Chang Chun-Hsiang
Journal: Cancer Research (2019)

Abstract This study examined the influence of cisplatin on host stroma and its consequence on metastasis using a metastatic melanoma tumor model. This preliminary result indicates that Gr-1+ cells could play important role on cisplatin treatment-directed liver metastasis. To further examine the role of Gr-1+ cells on this phenomena, Gr-1Ab was administered at day 16 after tumor inoculation. Results show that Gr-1Ab treatment could effectively decrease the Ly6G+ cells in both lung and liver and without significant reduced in lung-metastasis but, increased the metastasis in lung. To identify the effect of cisplatin treatment on B16-F0 melanoma metastasis, normal mice were treated with cisplatin prior to iv inject of B16-F0 melanoma cells. Cisplatin prevented treatment, similar to Gr-1 Ab therapy, decreased Ly6G+ cell in lung and liver tissue. And, it is minor difference of lung metastasis compare to Gr-1 Ab treatment, but more metastatic site than it. It demonstrates that cisplatin therapy induced liver-metastasis could associate with Ly6G+ cells. This study concludes that the cisplatin treatment could alter the preference of tumor metastasis, which is associated with the reduction of Ly6G+ cells It could be a potential target to enhance therapy efficiency. Citation Format: Chang Chun-Hsiang. Cisplatin treatment alters the preference of melanoma metastasis to liver associated with Ly6G positive cells [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 1105.
THE GENTLEMAN'S PILL
Journal: JAMA (1968)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A Harvey Anniversary: 1616-1916
Journal: JAMA (2016)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Diagnosis of oesophageal spasm by ergometrine provocation
Authors: H A. Davies, M D Kaye, J Rhodes, A M Dart, A Henderson
Journal: Gut (1983)

Diagnosis of oesophageal spasm by ergometrine provocation Sir,We have recently published our findings on oesophageal spasm and the value of ergometrine provocation in its diagnosis (Gut 1982; 23: 89-97).We misquoted figures from Buxton's study and reported three patients who died with coronary artery spasm after a dose of ergometrine which was 0 17 mg and not 1.7 mg as stated in our paper.Our recommendation, however, to give 0.5 mg of ergometrine is safe provided that the screening criteria are followed.These should include a normal 12-lead ECG obtained during spontaneous chest pain, and resuscitative facilities should be available during the ergometrine test.Responses to small doses of ergometrine -0.05 mg should first be assessed and after five minutes, incremental doses can then be given.
Supplemental folates in the therapy of Plasmodium falciparum malaria
Authors: M. J. Tong
Journal: JAMA (1970)

<i>Seventy-five US marines who were treated with pyrimethamine, chloroquine phosphate, and sulfisoxazole for</i>Plasmodium falciparum<i>malaria, were supplemented with either folic acid, folinic acid, or a placebo. A reduced incidence of anemia and leukopenia, a more rapid reticulocytosis, and an increased platelet response were seen in both the folic and folinic acid supplemented groups. The antimalarial effect of pyrimethamine was not inhibited by the addition of folates to the treatment regimen. Folate supplements are recommended when pyrimethamine is used in the therapy of </i>P falciparum<i>malaria</i>.
Pioneer Medicine in Western Pennsylvania.
Journal: JAMA (1927)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Viral Gastroenteritis Associated With Consumption of Raw Oysters—Florida, 1993
Journal: JAMA (1994)

During November 20-30, 1993, four county public health units (CPHUs) of the Florida Department of Health and Rehabilitative Services (HRS) in northwestern Florida conducted preliminary investigations of seven separate outbreaks of foodborne illness following consumption of raw oysters. On December 1, the HRS State Health Office initiated an investigation to characterize the illness, examine risk factors for oyster-associated gastroenteritis, and quantify the dose-response relation. This report presents the findings of these two investigations.
Pretraining for International Medical Graduates
Authors: Miguel Villalona-Calero
Journal: Annals of Internal Medicine (1993)

Letters1 March 1993Pretraining for International Medical GraduatesMiguel Villalona-Calero, MDMiguel Villalona-Calero, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-118-5-199303010-00027 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:As an international medical graduate who had residency and fellowship training in the United States and is currently working in an underserved area, I feel it necessary to add my views to the worthwhile suggestions in Dr. Levey's article [1]. I am concerned about the implications regarding humanistic and ethical behavior. Many foreign medical graduates are among the most humane and ethical people I have met during my years as a subintern, resident, and fellow in different hospital settings. It is the “House of God” philosophy so prevalent among U.S. graduates that still astonishes me.Furthermore, we ...REFERENCE1. Levey GS. Internal medicine and the training of international medical graduates: a time for open discussion and new approaches. Ann Intern Med. 1992; 117:403-7. Google Scholar Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 March 1993Volume 118, Issue 5Page: 396-398KeywordsAIDSBehaviorFellowshipsGraduate medical educationMedical educationMedicarePatientsResidencyRunning ePublished: 15 August 2000 Issue Published: 1 March 1993 Copyright & PermissionsCopyright © 1993 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
A Text-Book of Bacteriology
Journal: JAMA (1941)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Labelling Drugs
Authors: H. D. Beckett
Journal: BMJ (1966)

<b>Objective:</b> To study the effects of an acute therapeutic oral intake of β<sub>2</sub> agonist on performance and substrate response during supramaximal exercise in women. <b>Methods:</b> 12 healthy moderately trained female volunteers performed a Wingate test after ingestion of placebo (Pla) and salbutamol (Sal; 4 mg) according to a double-blind randomised crossover study. Blood samples were collected at rest, at the end of exercise and after 5 (r5), 10 (r10) and 15 (r15) min of passive recovery for adrenocorticotropic hormone (ACTH), growth hormone (GH), insulin, blood glucose and lactate measurements. <b>Results:</b> Peak power (PP) and mean power (MP) significantly increased whereas time to peak power was significantly shorter with Sal than with Pla (p&lt;0.05). No change was observed in the fatigue index. ACTH was not significantly modified but r15 growth hormone significantly decreased (p&lt;0.05) after the intake of Sal. Both blood INS and blood glucose were significantly increased by the intake of Sal during all the experiments (p&lt;0.01). Blood lactate was significantly increased by the intake of Sal compared with that of Pla (p&lt;0.05) after 10 and 15 min of passive recovery. <b>Conclusion:</b> From these data, acute therapeutic oral intake of Sal seems to induce, irrespective of the subjects’ gender, an improvement in performance during a supramaximal exercise—that is, increase in PP and MP. Further studies are necessary to clarify whether the mechanisms involved in the response to intake of Sal are linked to central and/or peripheral pathways.
Impact of external-beam radiation therapy on outcomes among patients with resected gastric cancer: A multi-institutional analysis.
Authors: Aslam Ejaz, Gaya Spolverato, Yuhree Kim, Malcolm Hart Squires, Sharon M. Weber, George A. Poultsides, Konstantinos Ioannis Votanopoulos, Mark Bloomston, Ryan C. Fields, David A. Kooby, Alexandra W. Acher, David J. Worhunsky, Doug S. Swords, Neil Saunders, Linda X. Jin, Clifford Suhyun Cho, Carl Richard Schmidt, Joseph M. Herman, Shishir Kumar Maithel, Timothy M. Pawlik
Journal: Journal of Clinical Oncology (2014)

84 Background: Use of perioperative chemotherapy (CTx) alone versus chemo-radiation therapy (cXRT) in the treatment of resectable gastric cancer remains varied. We sought to define the utilization and effect of CTx alone versus cXRT on patients having undergone curative-intent resection for gastric cancer. Methods: Using the multi-institutional U.S. Gastric Cancer Collaborative database, we identified 505 patients between 2000 and 2012 with gastric cancer who received perioperative therapy in addition to curative-intent resection. The impact of perioperative therapy on survival was analyzed by the use of propensity-score matching of clinicopathologic factors among patients who received CTx alone versus cXRT. Results: Median patient age was 62 years and the majority of patients were male (58%). Surgical resection involved either partial gastrectomy (54%) or total gastrectomy (46%). On pathology, median tumor size was 5.0 cm; most patients had a T3 (37%) or T4 (36%) lesion and lymph node metastasis (74%). Margin status was R0 in most patients (89%). 211 (42%) patients received perioperative CTx alone whereas the remaining 294 (58%) patients received 5-FU based cXRT. Factors associated with receipt of cXRT were younger age (OR 0.98), T3 tumors (OR 1.52), and lymph node metastasis (OR 2.03) (all P &lt; .05). Recurrence occurred in 214 (39%) patients. At a median follow-up of 28 months, median overall survival (OS) was 33.4 months and 5-year survival was 36.7%. Factors associated with worse OS included tumor size (HR 1.1), T-stage (HR 1.5), and lymph node metastasis (HR 1.58) (all P&lt;0.05). In contrast, receipt of cXRT was associated with improved long-term OS (CTx alone: 21 months vs. cXRT 45 months; p&lt;0.001). In the propensity-matched multivariate model that adjusted for tumor size, T-stage, and nodal status, cXRT remained associated with an improved long-term disease-free (HR 0.43) and overall (HR 0.41) survival (both P&lt;0.001). Conclusions: XRT was utilized in 58% of patients undergoing curative-intent resection for gastric cancer. Using propensity-matched analysis, cXRT was an independent factor associated with improved recurrence-free and overall survival.
Quantification of Two Aromatic Amine Mutagens, PBTA-1 and PBTA-2, in the Yodo River System
Authors: Takeshi Ohe, Nobue Takeuchi, Tetsushi Watanabe, Atsuko Tada, Haruo Nukaya, Yoshiyasu Terao, Hiroyuki Sawanishi, Teruhisa Hirayama, Takashi Sugimura, Keiji Wakabayashi
Journal: Environmental Health Perspectives (1999)

The levels of two aromatic amine mutagens, 2-[2-(acetylamino)-4-[bis(2-methoxyethyl)amino]-5-methoxyphenyl]-5-am ino-7-bromo-4-chloro-2H-benzotriazole (PBTA-1) and 2-[2-(acetylamino-4-[N-(2-cyanoethyl)ethylamino]-5-methoxyphenyl]-5-a mino-7-bromo-4-chloro-2H-benzotriazole (PBTA-2), were quantitatively analyzed in the Yodo River system in Japan. The river water samples were collected at nine sampling sites from the Yodo River system twice or three times between May and July in 1997. PBTA-1 and PBTA-2 in the river water samples were concentrated on blue rayon columns, partially purified by high-performance liquid chromatography (HPLC) on reverse-phase columns, then quantified by HPLC with an electrochemical detector. The amounts of PBTA-1 and PBTA-2 in the water samples were < 0.01-1.91 and < 0.01-2.25 ng/L, respectively. High levels of PBTA-1 and PBTA-2 were detected in the samples collected within 4 km downstream of two sewage plants, which are located along the banks of the Nishitakase River, a tributary of the Yodo River system, and these samples showed stronger mutagenicity in Salmonella typhimurium YG1024 with S9 mix than the other water samples. On the other hand, the river water samples from upstream of the sewage plant were weakly or not mutagenic and PBTA-1 and PBTA-2 were not detected. These results confirmed that a major source of PBTA-1 and PBTA-2 in the Yodo River system is effluent from the sewage plants and that discharged mutagens, including PBTA-1 and PBTA-2, are diluted and/or decomposed while moving down the Yodo River system.
Internal medicine
Authors: F. D. Gray
Journal: JAMA (1980)

Now is a good time, as we finish one decade and start a new one, to take stock of how internal medicine has fared. But to identify the single most important idea or event of a decade is a task I face with considerable awe. However, one outstanding trend has been the redirection of our focus from organs and tissues to cells. The change began long before the 1970s, but it became pervasive during this decade. Cellular and molecular biology is now a clinical reality to the physician at the bedside. The biologic concept of the cell has been with us more than two centuries, and the idea that the cell is a focus of disease germinated at approximately the time Virchow published his treatise on cellular pathology slightly more than 100 years ago. The first half of the 20th century saw little progress in clinical concepts of the cell,
Obliterative Vascular Changes in Four Human Kidney Homotransplants
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
CEREBRAL HEMORRHAGE FOLLOWING DIPHTHERIA.
Journal: JAMA (1897)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Public Acceptance of Mumps Immunization
Authors: Phillip H. Jones
Journal: JAMA (1969)

Live mumps vaccine was added to clinic and school immunization programs in 1968. Requests for clinic immunization were highest among children under 10 years of age and lowest among adults. In the school program, 13% of the fourth grade enrollment (37% of estimated susceptibles) requested vaccine while only 2% of 12th grade enrollment (10% of estimated susceptibles) requested vaccine. Motivation of adults and older teen-agers to seek immunization for themselves is probably so low that this approach will not significantly reduce the incidence of adult mumps. Immunization of children under 10 years is very acceptable to the public. Since over three fourths of all mumps cases occur in children under age 10, their protection through immunization should bring the added benefit of reducing the incidence of mumps in adults by reducing exposure of adults to children with mumps.