tbuckley/cabot-search huggingface dataset:
International Abstracts
Journal: JAMA (1989)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
GOVERNMENT SUPERVISION OF VACCINE VIRUS.
Journal: JAMA (1907)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Chylous Effusions into Intestine in Patient with Protein-Losing Gastroenteropathy
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Double-blind Study of Effect of 17-Hydroxyprogesterone Caproate on Abortion Rate
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Congenital bilateral absence of the vas deferens. A primarily genital form of cystic fibrosis
Authors: A. Anguiano
Journal: JAMA (1992)

<h3>Objective.</h3> —Almost all males with cystic fibrosis (CF) have absent vasa deferentia. It has been suggested that otherwise healthy males with congenital bilateral absence of the vas deferens (CBAVD), previously considered a distinct genetic entity, have an increased frequency of CF gene mutations. This study examined the genetic commonality of these two disorders. <h3>Design.</h3> —We typed six common CF gene mutations in 25 patients with CBAVD. Additional rare mutations were sought using single-stranded conformation polymorphisms and direct DNA sequencing. When rare mutations were found, they were sought in a large sample of both CF patients and obligate CF carriers to exclude them as polymorphisms. <h3>Setting.</h3> —All the patients presented to a male infertility clinic of a teaching hospital. <h3>Subjects.</h3> —Twenty-five unselected, unrelated azoospermic men with CBAVD, most of them of Northern European ancestry. <h3>Results.</h3> —Sixteen (64%) of the 25 men with CBAVD had at least one detectable CF mutation, 16 times the expected frequency (<i>P</i>&lt;.001). Moreover, we have thus far determined that three of these 16 men are compound heterozygotes, one of whom has a mutation not previously described. Analyses continue on patients who have yet to yield a detectable mutation. <h3>Conclusions.</h3> —Some, if not all, otherwise healthy men with CBAVD reflect a newly recognized, primarily genital, phenotype of CF. Prior to sperm aspiration to remedy infertility, CF mutation analysis should be recommended for them and their partners, as well as for their relatives. (<i>JAMA</i>. 1992;267:1794-1797)
The Joint Commission's view of externship programs
Authors: J. D. Porterfield
Journal: JAMA (1970)

At its Dec 13, 1969, meeting, the Board of Commissioners of the Joint Commission on Accreditation of Hospitals went on record as approving of the standards developed by the Student American Medical Association in its education externship program for junior and senior medical students from foreign medical schools who work in US hospitals. In a policy statement that came out of the December meeting, the Board of Commissioners stated that accredited hospitals participating in this SAMA program, and adhering to these published standards, would not thereby jeopardize their accreditation status. Although the Joint Commission is comfortable with the SAMA program for foreign student externships, it is concerned by the fact that there is no comparable program for students in US medical schools. Since no program does exist, the Joint Commission must depend, for accreditation purposes, on the endorsement of externship programs by deans of medical schools, and in doing so
The Deaf Adult
Authors: John B. De Hoff
Journal: JAMA (1972)

<h3>To the Editor.—</h3> There is not only a "Problem of the Deaf Child," as noted inThe Journal(221:303, 1972), but there is also the problem of the deaf people. Deafness evokes rejection behavior from the person who cannot hear and from the person who cannot make himself understood. Older deaf people reject hearing aids or use them improperly, and even partially deaf people are subject to reprimand or accusations of "not listening." For the blind, all sorts of organizations, aids, and sympathy are available. Partial blindness, with the possible exception of myopia, is recognized as a serious handicap. Can it be that our profession shares a responsibility for those divergent attitudes toward two crippling conditions, deafness and blindness? Is it perhaps due to the fact that Snellen charts are inexpensive and audiometers expensive? Have we, as a profession, more to offer the blind than the deaf?
Implications of New Data on Lead Toxicity for Managing and Preventing Exposure
Authors: Ellen K. Silbergeld
Journal: Environmental Health Perspectives (1990)

Recent advances in research on low-level lead poisoning point to the need to increase efforts to prevent exposure. Current biomedical consensus accepts that blood lead levels as low as 5 to 15 mcg/dL are risky to fetuses, young children, and adults. Lead at low dose is associated with increased blood pressure in adults, and chronic exposure has been associated in cohort studies with kidney disease and cancer. Data on lead toxicokinetics also points to the hazards of low-level, chronic exposure, since the lead that is accumulated over time in bone can be released at a relatively rapid rate during pregnancy and menopause. Sources that contribute to current lead exposure of the general population include unabated lead-based paint and contaminated soils, as well as lower level but pervasive sources in drinking water, food, and consumer products.
Incorrect Medication Reported
Authors: John Ioannidis
Journal: JAMA (2018)

Incorrect Medication Reported: In the News From the Food and Drug Administration item entitled "Generic for Opioid Use Disorder," 1 published in the July 17, 2018, issue of JAMA, an incorrect medication was reported.In the second paragraph, the second sentence should have read as follows: "Buprenorphine, naltrexone, and methadone are FDA-approved to help patients who misuse opioids."This article was corrected online.1. Voelker R. Generic for opioid use disorder.
Venereal disease control among homosexuals; An outreach program
Authors: M. G. Ritchey
Journal: JAMA (1975)

With the support and participation of area homosexual organizations and a local bar, the City Health Department developed an outreach/ education/screening program for venereal disease (VD) control. Venereal disease education and blood testing were conducted during four sequential Wednesday evenings in the bar on a volunteer basis, anonymously if requested. Of the 118 sera drawn, ten were reactive on serologic testing. Two of these reactive blood tests led to the discovery of two new cases of primary syphilis. No cultures were positive for<i>Neisseria gonorrhoeae</i>. The subject response rate confirms the value of an anonymous reporting method; the discovery of two cases of primary syphilis lends credence to case finding by field-screening a high-risk population. (<i>JAMA</i>232:509-510, 1975)
Electrodiagnosis
Authors: Donald S. Pierce
Journal: New England Journal of Medicine (1967)

THE rapid increase in the use of electronic devices in the various branches of clinical medicine has brought about considerable refinement and sophistication in the methods of electrodiagnosis and in the equipment available for the performance of electrodiagnostic procedures. Console-packaged equipment is readily available with which all commonly performed electrodiagnostic tests can be carried out. When it is desired to record more than two bioelectric phenomena concurrently or to combine clinical investigation with diagnostic testing, an almost infinite range of electric stimulating and recording equipment is available.The uses of electrodiagnosis have also been expanded over the past two decades . . .
THE PARASITIC ORIGIN OF MALIGNANT NEOPLASMS.
Journal: JAMA (1906)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Correction: Leukaemia and lymphoma among young people near Sellafield
Journal: BMJ (1990)

and lymphoma in West C(umbria Dr Valerie Beral was reluctant to accept the conclusion that radia- tion damage to sperm cells may be a cause of childhood cancer.TFhis reluctance stems partly from the facts that "7400 children of Japanese men who survived the atomic bomb explosions ... show, no hint of an increased risk of leukaemia . .." andi "the average exposure to external ionising radiation of the Japanese men was four times higher than that of the Sellafield workers."
Book Review Illustrations of Surgical Treatments, Instruments and Appliances . By Eric L. Farquharson, M.D., F.R.C.S.E., with a foreword by Sir John Fraser. 8°, cloth, 338 pp., with 259 illustrations and 57 plates. Baltimore: Williams &amp; Wilkins Company, 1939. $6.50.
Journal: New England Journal of Medicine (1940)
Lymphocyte subsets in healthy children during the first 5 years of life
Authors: T. Denny
Journal: JAMA (1992)

<h3>Objective.</h3> —To assess whether relative and absolute values of CD4 and CD8 lymphocytes and CD4/CD8 ratio change in relation to age, and to estimate the fifth and 95th percentiles for these values in children of various ages. <h3>Patients and Methods.</h3> —Phenotypic analysis of lymphocyte subsets was performed on blood samples from 208 healthy children, aged 1 through 59 months, using standard flow cytometric techniques. <h3>Results.</h3> —Regression analysis demonstrated that CD4 and CD8 lymphocyte counts declined significantly with advancing age (<i>P</i>&lt;.000001 and<i>P</i>=.03, respectively). Since CD4 and CD8 counts depend on total lymphocyte count, the percentage of total lymphocytes of each phenotype was also analyzed and demonstrated that the CD4 percentage was highly age dependent (<i>P</i>&lt;.000001). The CD8 percentage increased with age (<i>P</i>=.0001) but not as much as the CD4 percentage decreased. Median CD4 counts (fifth and 95th percentiles) for children 2 through 3,4 through 8,12 through 23, and 24 through 59 months of age were 2.83 (1.46 to 5.11), 2.95 (1.69 to 4.61), 2.07 (1.02 to 3.60), and 1.80 (0.90 to 2.86) × 109/L, respectively. <h3>Conclusion.</h3> —Healthy children's CD4 lymphocyte counts are considerably higher than previously established adult values. These data demonstrate that age is an important consideration in interpretation of lymphocyte subsets in children. This may be especially relevant in children who are infected with the human immunodeficiency virus, where CD4 lymphocyte values play a central role in monitoring disease progression and determining thresholds for medical interventions. (<i>JAMA</i>. 1992;267:1484-1488)
Abstract 9742: Counteractive Effects of Omentin-1 Against Atherogenesis
Authors: Kaho Watanabe, Rena Watanabe, Hanae Konii, Remina Shirai, Kengo Sato, Taka-aki Matsuyama, Hatsue Ishibashi-Ueda, Shinji Koba, Youichi Kobayashi, Tsutomu Hirano, Takuya Watanabe
Journal: Circulation (2015)

Introduction: Omentin-1, a novel adipocytokine expressed in visceral fat tissue, is negatively correlated with obesity, insulin resistance, and stable coronary artery disease (CAD). However, there have been no previous reports regarding the effects of omentin-1 on atherogenesis. Objective and Methods: We aimed to evaluate the atheroprotective effects of omentin-1 on human monocyte-derived macrophages, human aortic smooth muscle cells (HASMCs) in vitro , and aortic lesions in apolipoprotein E-deficient (ApoE -/- ) mice in vivo . The histological expression of omentin-1 in coronary artery lesions and epicardial adipose tissues and its plasma levels were compared between CAD and non-CAD patients. Results: Omentin-1 was abundantly expressed in human umbilical vein endothelial cells, macrophages, HASMCs, and human coronary artery SMCs in vitro . Omentin-1 promoted antiinflammatory M2 phenotype via PPAR-γ upregulation and NF-κB downregulation during differentiation of human monocytes into macrophages. Omentin-1 suppressed oxidized LDL-induced foam cell formation associated with downregulation of CD36, scavenger receptor class A, and acyl-CoA:cholesterol acyltransferase-1 and upregulation of neutral cholesterol ester hydrolase in human macrophages. In HASMCs, omentin-1 suppressed angiotensin II-induced migration and PDGF-BB-induced proliferation, and collagen-1 and collagen-3 expressions via ERK1/2 and NF-κB downregulation. Four-week infusion of omentin-1 into ApoE -/- mice retarded the development of aortic atherosclerotic lesions with reduced contents of monocytes/macrophages, SMCs, and collagen fibers. In addition, it increased peritoneal M2-activated macrophages, downregulated inflammasomes such as CRP, NF-κB, COX-2, and apoptosis-associated speck-like protein containing a caspase recruitment domain, and lowered plasma total cholesterol levels in ApoE -/- mice. Omentin-1 levels were markedly reduced in coronary endothelium and epicardial fat but increased in plasma and atheromatous plaques (macrophages/SMCs) in CAD patients compared with non-CAD patients. Conclusions: Our translational research provided the first evidence that omentin-1 may serve as a novel therapeutic target for atherosclerosis and CAD.
ESOPHAGEAL DIVERTICULUM
Authors: FRANK H. LAHEY
Journal: JAMA (1933)

This paper deals with the experiences of my associates and myself with forty-five patients operated on for esophageal pulsion diverticulum. In it, I hope to present some of our mistakes and difficulties, together with the measures we have taken to overcome them. Historical references are omitted in this discussion, since they may be found in previous articles I have written on the subject<sup>1</sup>and because all of the allotted time will be required to cover the subject from the standpoint of the proposal set forth in the previous paragraph. Symptomatology needs little mention, since it consists only of varying difficulty in swallowing and the regurgitation of previously swallowed food. A discussion of the relation of symptoms to sacs of varying size will also be found in my previous articles on this subject.<sup>2</sup> Esophageal pulsion diverticulum is such a typical and definite entity that it requires but little description.
Cancer Risk Assessment of Extremely Low Frequency Electric and Magnetic Fields: A Critical Review of Methodology
Authors: Joyce McCann, Leeka Kheifets, Charles Rafferty
Journal: Environmental Health Perspectives (1998)

A comparative analysis was performed of the phenotype and function of peripheral blood leukocytes of two age-matched cohorts of industrial workers in chemical plants, one of which was exposed occupationally to high concentrations of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Median actual TCDD burdens were 116 ng/kg and 4 ng/kg, respectively. The phenotype analysis of peripheral blood mononuclear cells (PBMC) revealed no significant differences in the proportions of CD3, CD4, or CD8+ T lymphocytes, of CD16+ natural killer cells, and of CD19+ B lymphocytes. However, in PBMC of the TCDD-exposed workers; the proportion of CD8+ memory T cells (CD45R0+) was significantly higher, and that of lymphocytes with naive phenotype (CD45RA+) was significantly lower than in PBMC of the control group. Polyclonal and antigen-specific T-cell activation was assessed in parallel in isolated PBMC as well as in diluted whole blood cultures. In both culture systems the polyclonally stimulated cytokine release did not differ significantly between the two cohorts; however, we found a significantly reduced interferon gamma release in diluted whole blood cultures but not in isolated PBMC cultures of the TCDD-exposed cohort when we performed an antigen-specific T-cell stimulation with tetanus-toxoid. Therefore, we propose that exposure of individuals to high doses of TCDD can partially impair in the "blood milieu" those T-cell/monocyte interactions that are essential for antigen-specific T-cell responses, whereas isolated PBMC of the same donors appear functionally less affected.
Breast Cancer in Postmenopausal Women After Hormone Therapy
Authors: R. Kent Hermsmeyer, Juan Carlos Kaski, Theresa L. Thompson
Journal: JAMA (2011)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Electroconvulsive therapy in patients with pacemakers
Authors: P. Abiuso
Journal: JAMA (1978)

A patient with an R-wave inhibited permanent pacemaker required electroconvulsive therapy (ECT). Possible interference by this therapy with pacer functioning through external interference or internal interference by inhibitory myopotentials was eliminated by temporary conversion to fixed rate pacing before ECT. (<i>JAMA</i>240:2459-2460, 1978)