Bismuth Nephrotoxicity
Authors: RUSSELL E. RANDALL
Journal: Annals of Internal Medicine (1972)

Letters, Comments, and Corrections1 September 1972Bismuth NephrotoxicityRUSSELL E. RANDALL JR., M.D., RAPHAEL J. OSHEROFF, M.D., SEYMOUR BAKERMAN, M.D., JOHN G. SETTER, M.D.RUSSELL E. RANDALL JR., M.D.Search for more papers by this author, RAPHAEL J. OSHEROFF, M.D.Search for more papers by this author, SEYMOUR BAKERMAN, M.D.Search for more papers by this author, JOHN G. SETTER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-77-3-481 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Bismuth nephrotoxicity usually results in acute oliguric renal failure (1), although transitory proximal tubular dysfunction has followed the ingestion of bismuth sodium triglycollamate (2). We have studied a 7-year-old boy who developed severe oliguric renal failure after an intramuscular injection of 200 mg of bismuth thioglycollate for warts (verruca vulgaris). A severe uremic syndrome was managed by hemodialysis for 10 days, at which time spontaneous diuresis occurred with subsequent complete recovery. We recorded certain laboratory data that may provide valuable diagnostic clues to the presence of heavy metal poisoning.During the acute illness the pattern of increased...References1. URIZARVERNIER RR: Bismuth nephropathy. JAMA 198: 187-189, 1966 CrossrefMedlineGoogle Scholar2. CZERWINSKIGINN AH: Bismuth nephrotoxicity. Am J Med 37:969-975, 1964 CrossrefMedlineGoogle Scholar3. SAKATIDEVINEDEVINE IPC: Serum lactic dehydrogenase in acute renal infraction and ischemia. N Engl J Med 278:721-723, 1968 CrossrefMedlineGoogle Scholar4. RINGOIR S: LDH isoenzyme pattern of rat kidney in mercurial intoxication. Nephron (Basel) 7:538-544, 1970 CrossrefMedlineGoogle Scholar5. TICKTINTRUJILLO HN: Serum enzymes in diagnosis, in Disease a Month. Chicago, Yearbook Medical Publishers, Inc., June 1966, p. 15 CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Department of Medicine and Pathology Medical College of Virginia Health Science Division Virginia Commonwealth University Richmond, Va. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByBarium- and Bismuth-loaded Clinoptilolite Micro- and Nano-Particles as Proposed New Efficient Contrast AgentsEffective Radiotherapy in Tumor Assisted by Ganoderma lucidum Polysaccharide-Conjugated Bismuth Sulfide Nanoparticles through Radiosensitization and Dendritic Cell ActivationArsenic, Antimony, and BismuthUrinary tractBismuthArsenic, Antimony, and BismuthAcute renal failure after overdose of colloidal bismuth subcitrateSafety Profile of Bismuth-Containing MedicationsBISMUTH TOXICITY—A REASSESSMENTPharmacokinetics and Toxicity of Bismuth CompoundsToxicological Significance of MetallothioneinMetallothionein and its Involvement in Heavy Metal Induced NephropathyToxische OsteopathienToxische Osteopathien 1 September 1972Volume 77, Issue 3Page: 481-482KeywordsBismuthHeavy metalsIngestionIntramuscular injectionsRenal failureResearch laboratoriesSodiumWarts Issue Published: 1 September 1972 PDF DownloadLoading ...