tbuckley/cabot-search huggingface dataset:
Viruses and oysters.
Journal: BMJ (1967)

mating to the normal diploid value seem to be relatively less active.Hitherto it has often been difficult to ensure that sufficiently representative tissue has been obtained at biopsy to allow a reliable estimate of invasion, but with this new method it seems that the difficulty has at least been partly overcome.Unfortunately with existing techniques only about one-half of the tumours examined have shown sufficient mitotic activity on which to base an opinion, but there can be little doubt that any positive information gained has amplified the histological picture.
Tuberculous brain abscess and Toxoplasma encephalitis in a patient with the acquired immunodeficiency syndrome
Authors: M. A. Fischl
Journal: JAMA (1985)

INFECTIOUS diseases of the central nervous system among immunocompromised patients are not uncommon but rarely involve more than one pathogen.<sup>1</sup><i>Mycobacterium tuberculosis</i>is an infrequent cause of central nervous system infection among immunocompromised patients.<sup>2,3</sup>When seen, meningitis is by far the most common presentation. Occurrence of a tuberculous brain abscess is rare.<sup>4-8</sup> <i>Toxoplasma</i>encephalitis has been recognized as one of the more common central nervous system infections among patients with the acquired immunodeficiency syndrome (AIDS). Concomitant infections, although uncommon, may be an emerging problem. The present report summarizes our experience with a patient who had a tuberculous brain abscess and concomitant<i>Toxoplasma</i>encephalitis. <h3>Report of a Case</h3> A 22-year-old Haitian woman was admitted to the hospital with a nine-month history of fever, watery diarrhea, anorexia, and a 9.1-kg weight loss. A three-month history of tingling and progressive weakness of the left upper and lower extremities, with inability
Medical Journal of Australia, Sydney
Journal: JAMA (1969)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Sudden, unexplained nocturnal death syndrome and night terrors
Authors: R. B. Melles
Journal: JAMA (1987)

<h3>To the Editor.—</h3> We read with great interest the recent correspondence suggesting sleep apnea as a possible explanation for the sudden, unexplained nocturnal death syndrome (SUNDS).<sup>1,2</sup>We would like to offer a different pathophysiological mechanism that we suspect is behind many of these deaths. The SUNDS occurs largely in young, previously healthy Asian men and includes<i>Bangungut</i>in the Philippines,<i>Pokkuri</i>in Japan, and sudden, unexplained nocturnal deaths among Southeast Asians in the United States. Ventricular fibrillation is thought to be the common physiological mechanism of these deaths.<sup>3</sup>Special postmortem cardiac studies reported by Kirschner et al<sup>2</sup>and previously by others<sup>4,5</sup>have documented abnormalities of the cardiac conduction system and cardiomegaly in victims of SUNDS. These cardiac defects are not manifest during the victim's life, and the event that provokes the fatal arrhythmia has never been explained. Our review of the clinical descriptions of the victims
Lipid lowering drug therapy initiated during hospitalization for acute MI is associated with lower postdischarge 1-year mortality Robert P. Giugliano, Elliott M. Antman, Susan L. Thompson, Carolyn H. McCabe, Eugene Braunwald. Bringham and Women's Hosital, Boston, MA, Nottingham Clinical Research Group, Nottingham, United Kingdom
Journal: Journal of the American College of Cardiology (2001)
The Alcohol Hangover
Authors: Jeffrey Wiese, Michael Shlipak
Journal: Annals of Internal Medicine (2001)

Letters20 March 2001The Alcohol HangoverJeffrey Wiese, MD and Michael Shlipak, MD, MPHJeffrey Wiese, MDUniversity of California, San Francisco; Veterans Affairs Medical Center (Wiese, Shlipak) and Michael Shlipak, MD, MPHUniversity of California, San Francisco; Veterans Affairs Medical Center (Wiese, Shlipak)Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-134-6-200103200-00028 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:Mr. Becker is correct in pointing out that the 1992 estimates from the National Institute on Drug Abuse and National Institute on Alcohol Abuse and Alcoholism are not specifically directed at the cost of the alcohol hangover. We regret that this statistic may have been misleading. It is important to note, however, that both of these models emphasize the chronic alcoholic and may underestimate the total lost productivity due to light-to-moderate drinking (1).The light-to-moderate drinker has fewer and less frequent missed work days than the chronic alcoholic, and this makes detecting lost productivity of this group using ...References1. New federally funded study estimates total cost of alcohol and drug abuse at $246 billion in 1992. Psychiatr Serv. 1998; 49:1110. [PMID: 0009712228] Google Scholar2. Kreitman N. Alcohol consumption and the preventive paradox. Br J Addict. 1986;81:353-63. [PMID: 0003461846] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: University of California, San Francisco; Veterans Affairs Medical Center (Wiese, Shlipak) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoThe Alcohol Hangover Jeffrey G. Wiese , Michael G. Shlipak , and Warren S. Browner The Alcohol Hangover Jeff Becker Metrics Cited ByRandomised double-blind placebo-controlled intervention study on the nutritional efficacy of a food for special medical purposes (FSMP) and a dietary supplement in reducing the symptoms of veisalgiaTelevision and Adolescent Use of Over-the-Counter Analgesic Agents 20 March 2001Volume 134, Issue 6Page: 534KeywordsAlcoholicsAlcoholismAlcoholsDrug abuseEmotions ePublished: 20 March 2001 Issue Published: 20 March 2001 CopyrightCopyright © 2001 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...
The One-Child Family and Violent Criminality: A 31-Year Follow-Up Study of the Northern Finland 1966 Birth Cohort
Authors: L. Kemppainen
Journal: American Journal of Psychiatry (2001)

OBJECTIVE: Serious defects in social skills acquired during childhood may be associated with aggressive behavior in later life. The authors studied whether being an only child was associated with criminality in adulthood and, secondly, if parental factors increased the putative risk. METHOD: The authors used an unselected, prospectively collected large birth cohort. Data on crimes were linked with being an only child as well as with perinatal risk and maternal and paternal psychological risk factors among male subjects. RESULTS: The risk for violent crimes later in life was elevated among the only children. If perinatal or parental risks were combined with being an only child, the odds ratios for violent offending increased four-fold to eight-fold. A corresponding risk increase between being an only child and nonviolent offending was not detected. CONCLUSIONS: These results support the hypothesis that growing up as an only child is associated with violent criminality among male subjects.
CARDIAC ARRHYTHMIAS AND SODIUM DIPHENYLHYDANTOIN-AN APPRAISAL
Journal: JAMA (1967)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
An Outbreak of Hepatitis A Associated with Green Onions
Authors: Charlotte Wheeler, Tara M. Vogt, Gregory L. Armstrong, Gilberto Vaughan, Andre Weltman, Omana V. Nainan, Virginia Dato, Guoliang Xia, Kirsten Waller, Joseph Amon, Teresa M. Lee, Angela Highbaugh-Battle, Cambria Hembree, Stephanie Evenson, Michael A. Ruta, Ian T. Williams, Anthony E. Fiore, Beth P. Bell
Journal: New England Journal of Medicine (2005)

In November 2003, a large hepatitis A outbreak was identified among patrons of a single Pennsylvania restaurant. We investigated the cause of the outbreak and factors that contributed to its unprecedented size.
Table of Contents
Authors: Holly Kramer, Adedamola Soyibo, Terrence Forrester, Michael Boyne, Talar Markossian, Ramon Durazo-Arvizu, Amy Luke, Richard Cooper, Francesco Emma, Dieter Haffner, Alexis Hofherr, Tilman Busch, Michael Köttgen, Tomas Ganz, Alan Jardine, Anders Hartmann, Hallvard Holdaas, Laurence Beck, David Salant, Roland Schmitt, Alain Meyrier, Patrick Niaudet, Timo Brandenburger, Antonio Somoza, Yvan Devaux, Johan Lorenzen, Natsuko Tokonami, Eric Olinger, Huguette Debaix, Pascal Houillier, Olivier Devuyst
Journal: Kidney International (2018)
India Adds Compulsory Drug Licenses
Journal: Cancer Discovery (2013)

Abstract The Indian government granted compulsory licenses for 3 cancer drugs, including breast cancer agents Herceptin (trastuzumab; Genentech) and Ixempra (ixabepilone; Bristol-Myers Squibb) and leukemia therapeutic Sprycel (dasatinib; Bristol-Myers Squibb). The licenses allow Indian companies to make and sell generic versions of the drugs at below-market rates.
Can Irradiation Destroy Metastatic Pelvic Lymph Nodes?
Authors: Felix Rutledge
Journal: JAMA (1965)

That irradiation is ineffective in the control of nodal metastases from cervical carcinoma is a cherished belief of some authorities, particularly those who prefer surgical treatment. This belief, however, is largely based on experience with the older methods of x-ray treatment, methods which are inadequate by modern standards. Today, an increasing amount of evidence indicates that, with apparatus now available, a cancerocidal dose of irradiation can indeed be delivered to the pelvic nodes. The opinion that irradiation was ineffective was formed from two observations: (1) Pelvic nodes excised after irradiation treatment sometimes contain metastatic foci; (2) The first sign of recurrence was often a palpable pelvic node for patients who were treated by irradiation and who did not have anykind of surgical treatment. The inference was that the radiosensitive primary lesion was destroyed, but the nodal disease was not radiosensitive, and therefore, was not destroyed. There was, also, evidence,
HOSPITAL SERVICE IN THE UNITED STATES
Journal: JAMA (1949)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A BCL6/BCOR/SIRT1 Complex Triggers Neurogenesis and Suppresses Medulloblastoma by Repressing Sonic Hedgehog Signaling
Authors: Luca Tiberi, Jérôme Bonnefont, Jelle van den Ameele, Serge-Daniel Le Bon, Adèle Herpoel, Angéline Bilheu, Beverly W. Baron, Pierre Vanderhaeghen
Journal: Cancer Cell (2015)
Archives of Internal Medicine, Chicago
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Preventive services in clinical practice: designing the periodic health examination
Authors: R. S. Lawrence
Journal: JAMA (1987)

In this issue ofThe Journal, the US Preventive Services Task Force presents the first in a series of background articles and recommendations for preventive measures that can be incorporated into personal health services.<sup>1</sup>The periodic health examination has largely replaced the annual physical examination, and the changing patterns of morbidity and major risk factors call for more integration of clinical preventive services into office visits triggered by acute or chronic symptomatic disease. In the 1920s, the American Medical Association and the Metropolitan Life Insurance Company first endorsed the annual physical examination as conferring long-term health benefits. Generations of physicians and patients came to regard the annual examination as the keystone of preventive medicine. In the 1970s, increasing cost consciousness, changing expectations of patients, and refined methods for studying the efficacy of diagnostic tests and maneuvers raised serious questions about the value of the annual checkup.<sup>2</sup>Clinicians began
HISTOPLASMOSIS
Journal: JAMA (1961)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Book Review Diseases of the Nervous System, Described for Practitioners and Students . By F. M. R. Walshe, O.B.E., M.D., D.Sc., F.R.C.P. (Lond.), D.Sc. (hon.). Second edition. 8°, cloth, 35 pp., with 32 illustrations. Baltimore: The Williams and Wilkins Company, 1941. $4.50.
Journal: New England Journal of Medicine (1942)
Familiality of Obsessive-Compulsive Disorder in Nonclinical and Clinical Subjects
Authors: Hans Grabe
Journal: American Journal of Psychiatry (2006)

Objective: Studies of the familiality of obsessive-compulsive disorder (OCD) have yielded inconsistent results. This study compared the familial aggregation of OCD in first-degree relatives of community subjects with never-treated OCD, outpatients with OCD, and comparison subjects. Method: Fifteen persons from the community with untreated OCD were matched on age and interview type (direct or through family informants) with 90 OCD patients from four treatment facilities and 70 comparison subjects. Direct or indirect interviews using the German-language version of the Schedule for Affective Disorders and Schizophrenia—Lifetime Version for Anxiety Disorders (DSM-IV) were obtained from 58, 285, and 247 first-degree relatives, respectively, of the three groups. The rate of OCD in case versus comparison relatives was assessed with chi-square tests, and odds ratios were calculated for risk estimation. Cox proportional hazards analysis was used to estimate the age-related risk of relatives of being affected by OCD. Results: Cox proportional hazards analyses revealed a 6.2-fold higher risk (hazard ratio) for relatives of all OCD cases for definite OCD and a 2.2–fold higher risk for subclinical OCD compared with relatives of comparison subjects. For relatives of community subjects with OCD, the risk for definite OCD (10.3% versus 5.6%) was 1.6, and the risk for subclinical OCD (15.4% versus 4.1%) was 3.4 compared with relatives of OCD patients from treatment sites. Conclusions: These results from the first controlled European family study of OCD confirm earlier U.S. data on the familiality of OCD in patients recruited from treatment facilities. The finding of a comparable familial aggregation of definite OCD and a higher familial aggregation of subclinical OCD in relatives of never-treated persons with OCD from the community strongly supports the impact of familial-genetic factors in OCD.
Correction to: PiggyBac mutagenesis and exome sequencing identify genetic driver landscapes and potential therapeutic targets of EGFR-mutant gliomas
Authors: Imran Noorani, Jorge de la Rosa, Yoon Ha Choi, Alexander Strong, Hannes Ponstingl, M. S. Vijayabaskar, Jusung Lee, Eunmin Lee, Angela Richard-Londt, Mathias Friedrich, Federica Furlanetto, Rocio Fuente, Ruby Banerjee, Fengtang Yang, Frances Law, Colin Watts, Roland Rad, George Vassiliou, Jong Kyoung Kim, Thomas Santarius, Sebastian Brandner, Allan Bradley
Journal: Genome biology (2020)

An amendment to this paper has been published and can be accessed via the original article.
End of Life
Journal: JAMA (1998)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE PUBLIC SERVICE.
Journal: JAMA (1896)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Cigarette Smoking—Attributable Mortality and Years of Potential Life Lost—United States, 1990
Journal: JAMA (1993)

Cigarette smoking is the single most preventable cause of premature death in the United States. An estimated 390,000 smoking-attributable deaths in the United States occurred in 1985, and more than 434,000 deaths occurred in 1988; in 1988, an estimated 1,198,887 years of potential life lost (YPLL) before age 65 were attributed to smoking. To estimate the national impact of cigarette smoking on mortality and YPLL, calculations were performed using the Smoking-Attributable Mortality, Morbidity, and Economic Cost (SAMMEC) software. This report summarizes the results of this analysis.