Effects on Health Outcomes of a Mediterranean Diet With No Restriction on Fat Intake
Authors: Miguel A. Martínez-González, Ramón Estruch, Dolores Corella, Emilio Ros, Montse Fitó, Lukas Schwingshackl, Jordi Salas-Salvadó
Journal: Annals of Internal Medicine (2017)

Letters7 March 2017Effects on Health Outcomes of a Mediterranean Diet With No Restriction on Fat IntakeMiguel A. Martínez-González, MD, MPH, PhD, Ramón Estruch, MD, PhD, Dolores Corella, PhD, Emilio Ros, MD, PhD, Montse Fitó, MD, PhD, Lukas Schwingshackl, PhD, and Jordi Salas-Salvadó, MD, PhDMiguel A. Martínez-González, MD, MPH, PhDFrom University of Navarra, Pamplona, Spain; Hospital Clinic, Barcelona, Spain; University of Valencia, Valencia, Spain; Centro de Investigación en Red Fisiopatología de la Obesidad y Nutrición, Madrid, Spain; Instituto Municipal de Investigaciones Médicas, Barcelona, Spain; German Institute of Human Nutrition, Potsdam, Germany; University Rovira Virgili, Reus (Tarragona), Spain., Ramón Estruch, MD, PhDFrom University of Navarra, Pamplona, Spain; Hospital Clinic, Barcelona, Spain; University of Valencia, Valencia, Spain; Centro de Investigación en Red Fisiopatología de la Obesidad y Nutrición, Madrid, Spain; Instituto Municipal de Investigaciones Médicas, Barcelona, Spain; German Institute of Human Nutrition, Potsdam, Germany; University Rovira Virgili, Reus (Tarragona), Spain., Dolores Corella, PhDFrom University of Navarra, Pamplona, Spain; Hospital Clinic, Barcelona, Spain; University of Valencia, Valencia, Spain; Centro de Investigación en Red Fisiopatología de la Obesidad y Nutrición, Madrid, Spain; Instituto Municipal de Investigaciones Médicas, Barcelona, Spain; German Institute of Human Nutrition, Potsdam, Germany; University Rovira Virgili, Reus (Tarragona), Spain., Emilio Ros, MD, PhDFrom University of Navarra, Pamplona, Spain; Hospital Clinic, Barcelona, Spain; University of Valencia, Valencia, Spain; Centro de Investigación en Red Fisiopatología de la Obesidad y Nutrición, Madrid, Spain; Instituto Municipal de Investigaciones Médicas, Barcelona, Spain; German Institute of Human Nutrition, Potsdam, Germany; University Rovira Virgili, Reus (Tarragona), Spain., Montse Fitó, MD, PhDFrom University of Navarra, Pamplona, Spain; Hospital Clinic, Barcelona, Spain; University of Valencia, Valencia, Spain; Centro de Investigación en Red Fisiopatología de la Obesidad y Nutrición, Madrid, Spain; Instituto Municipal de Investigaciones Médicas, Barcelona, Spain; German Institute of Human Nutrition, Potsdam, Germany; University Rovira Virgili, Reus (Tarragona), Spain., Lukas Schwingshackl, PhDFrom University of Navarra, Pamplona, Spain; Hospital Clinic, Barcelona, Spain; University of Valencia, Valencia, Spain; Centro de Investigación en Red Fisiopatología de la Obesidad y Nutrición, Madrid, Spain; Instituto Municipal de Investigaciones Médicas, Barcelona, Spain; German Institute of Human Nutrition, Potsdam, Germany; University Rovira Virgili, Reus (Tarragona), Spain., and Jordi Salas-Salvadó, MD, PhDFrom University of Navarra, Pamplona, Spain; Hospital Clinic, Barcelona, Spain; University of Valencia, Valencia, Spain; Centro de Investigación en Red Fisiopatología de la Obesidad y Nutrición, Madrid, Spain; Instituto Municipal de Investigaciones Médicas, Barcelona, Spain; German Institute of Human Nutrition, Potsdam, Germany; University Rovira Virgili, Reus (Tarragona), Spain.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/L16-0589 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:We are concerned by the statements on weak evidence of benefit of the traditional Mediterranean diet in Bloomfield and colleagues' systematic review (1). Rating the available evidence as limited is unfair. The quality and quantity of scientific evidence supporting the benefits of this diet are impressive and are lacking in other dietary patterns.The PREDIMED (Prevención con Dieta Mediterránea) trial, a low-risk-of-bias study, was not designed to assess differences in all-cause mortality. The primary end point was cardiovascular disease—including myocardial infarction, stroke, and cardiovascular death, as stated in the protocol (2)—but not all-cause mortality. This is also ...References1. Bloomfield HE, Koeller E, Greer N, MacDonald R, Kane R, Wilt TJ. Effects on health outcomes of a Mediterranean diet with no restriction on fat intake. A systematic review and meta-analysis. Ann Intern Med. 2016;165:491-500. [PMID: 27428849]. doi:10.7326/M16-0361 LinkGoogle Scholar2. Estruch R, Ros E, Salas-Salvadó J, Covas MI, Corella D, Arós F, et al; PREDIMED Study Investigators. Primary prevention of cardiovascular disease with a Mediterranean diet. N Engl J Med. 2013;368:1279-90. [PMID: 23432189] doi:10.1056/NEJMoa1200303 CrossrefMedlineGoogle Scholar3. Sofi F, Macchi C, Abbate R, Gensini GF, Casini A. Mediterranean diet and health status: an updated meta-analysis and a proposal for a literature-based adherence score. Public Health Nutr. 2014;17:2769-82. [PMID: 24476641] doi:10.1017/S1368980013003169 CrossrefMedlineGoogle Scholar4. Martinez-Gonzalez MA, Martin-Calvo N. Mediterranean diet and life expectancy; beyond olive oil, fruits, and vegetables. Curr Opin Clin Nutr Metab Care. 2016;19:401-407. [PMID: 27552476] CrossrefMedlineGoogle Scholar5. Schwingshackl L, Hoffmann G. Diet quality as assessed by the Healthy Eating Index, the Alternate Healthy Eating Index, the Dietary Approaches to Stop Hypertension score, and health outcomes: a systematic review and meta-analysis of cohort studies. J Acad Nutr Diet. 2015;115:780-800. [PMID: 25680825] doi:10.1016/j.jand.2014.12.009 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From University of Navarra, Pamplona, Spain; Hospital Clinic, Barcelona, Spain; University of Valencia, Valencia, Spain; Centro de Investigación en Red Fisiopatología de la Obesidad y Nutrición, Madrid, Spain; Instituto Municipal de Investigaciones Médicas, Barcelona, Spain; German Institute of Human Nutrition, Potsdam, Germany; University Rovira Virgili, Reus (Tarragona), Spain.Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L16-0589. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoEffects on Health Outcomes of a Mediterranean Diet With No Restriction on Fat Intake Hanna E. Bloomfield , Eva Koeller , Nancy Greer , Roderick MacDonald , Robert Kane , and Timothy J. Wilt Effects on Health Outcomes of a Mediterranean Diet With No Restriction on Fat Intake Angeliki Papadaki and J. Alfredo Martinez Effects on Health Outcomes of a Mediterranean Diet With No Restriction on Fat Intake Hanna E. Bloomfield , Nancy Greer , Robert Kane , and Timothy J. Wilt Metrics Cited byOne-year nutrition counselling in the context of a Mediterranean diet reduced the dietary inflammatory index in women with breast cancer: a role for the dietary glycemic indexModulation of 1,2-Dicarbonyl Compounds in Postprandial Responses Mediated by Food Bioactive Components and Mediterranean DietDietary inflammatory index and all-cause mortality in large cohorts: The SUN and PREDIMED studiesThe Mediterranean Diet and Cardiovascular Health 7 March 2017Volume 166, Issue 5Page: 378KeywordsCohort studiesDietDisclosureFatsForecastingMortalityMyocardial infarctionRheumatoid arthritisSystematic reviewsType 2 diabetes ePublished: 7 March 2017 Issue Published: 7 March 2017 Copyright & PermissionsCopyright © 2017 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...