Call for Comments on a Proposal To Improve Reporting of Clinical Trials in the Biomedical Literature
Authors: Working Group on Recommendations for Reporting of Clinical Trials in the Biomedical Literature.
Journal: Annals of Internal Medicine (1994)

Position Papers1 December 1994Call for Comments on a Proposal To Improve Reporting of Clinical Trials in the Biomedical LiteratureWorking Group on Recommendations for Reporting of Clinical Trials in the Biomedical Literature.Working Group on Recommendations for Reporting of Clinical Trials in the Biomedical Literature.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-121-11-199412010-00015 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Published guidelines for reporting clinical-research data range from the succinct paragraph on statistics in the "Uniform Requirements for Manuscripts Submitted to Biomedical Journals" [1] to articles of differing detail [2-7] and books written for the clinical researcher [8-10]. Despite such excellent resources in the biomedical literature, neither investigators reporting clinical trials nor journal editors selecting reports of trials for publication follow those guidelines consistently. For this reason, a working group of medical journal editors, biostatisticians, researchers, and editors from biomedical institutions met to consider how reporting of clinical-trials data might be made more consistent and complete. The group proposed that ...References1. International Committee of Medical Journal Editors. Uniform requirements for manuscripts submitted to biomedical journals. JAMA. 1993; 269:2282-6. Google Scholar2. Altman DG, Bland JM. Improving doctors' understanding of statistics. J R Statist Soc A. 1991; 54(Pt 2):223-67. Google Scholar3. Altman DG, Gore SM, Gardner MJ, Popcock SJ. Statistical guidelines for contributors to medical journals. Br Med J. 1983; 286:1489-93. Google Scholar4. Bailar JC 3d, Mosteller F. Guidelines for statistical reporting in articles for medical journals. Amplifications and explanations. Ann Intern Med. 1988; 108:266-73. Google Scholar5. Chalmers TC, Smith H Jr, Blackburn B, Silverman B, Schroeder B, Reitman D, et al. A method for assessing the quality of a randomized control trial. Controlled Clin Trials. 1981; 2:31-49. Google Scholar6. Finney DJ, Clarke BC. Guest editorial: code for presentation of statistical analyses. Phil Trans R Soc Lond B. 1992; 337:381-2 (code first appeared in Proc R Soc Lond B. 1992; 249:1-2). Google Scholar7. Murray GD. The task of a statistical referee. Br J Surg. 1988; 75:664-7. Google Scholar8. Bailar JC 3d, Mosteller F, eds. Medical Uses of Statistics. 2nd ed. Waltham, Massachusetts: NEJM Books; 1992:449. Google Scholar9. Glantz SA. Primer of Biostatistics. 3rd ed. New York: McGraw-Hill; 1992; 440. Google Scholar10. Dawson-Saunders B, Trapp RG. Basic and Clinical Biostatistics. 2nd ed. Norwalk, Connecticut: Appleton & Lange; 1994:344. Google Scholar11. Olkin I. Reconcilable differences: gleaning insight from conflicting scientific studies. The Sciences. 1992; (Jul/Aug):30-6. Google Scholar Author, Article, and Disclosure InformationAffiliations: For members of the Working Group, see the Appendix.Corresponding Author: Susan Eastwood, ELS(D), Department of Neurological Surgery, Box 0926, c/o The Editorial Office, 1360 Ninth Avenue, Suite 210, San Francisco, CA 94122. 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