tbuckley/cabot-search huggingface dataset:
Indications for aortocoronary bypass graft surgery, 1979. Council on Scientific Affairs
Journal: JAMA (1979)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Radiology
Authors: Norman E. Leeds
Journal: JAMA (1990)

Exciting events in diagnostic radiology occurring over the past year include the development of a model of atherosclerosis at the University of Washington (Seattle) Medical Center by Goldman et al<sup>1</sup>using Yucatan microswine. The lesions are established by placing the animal on a high-fat diet and using intra-arterial balloons to denude the vascular endothelium. Histopathologic lesions identical to those observed in human atherosclerotic vascular disease may not develop for 5 or more months. The lesions reveal a fibrous cap with intimal hyperplasia, foam cells, necrosis, and calcification. The advantage of producing such lesions in this model is that arteries similar in size to the superficial femoral artery are accessible. This model was developed for the purpose of evaluating angioplasty devices, including various balloons, instruments for atherectomies, and lasers. Effectiveness of therapy, complications, and the occurrence of restenosis may be studied using this model. In addition, it can be used
Bedside Medicine
Authors: Samuel Vaisrub
Journal: JAMA (1967)

Retaining a distinctive personal style despite double authorship, this discursive book deals authoritatively with a wide range of clinical topics. The approach is often subjective. Personal preferences are reflected in selection and arrangement of subjects, in nuances of emphasis, and in omissions as conspicuous as that of alcohol cardiomyopathy from the cardiomyopathy section. Absence of references, illustrations, and diagrams enhance the subjective informality of the book, and paradoxically, its appeal to the sophisticated reader who seeks respite from customary patterns that we find in most books. <i>Bedside Medicine</i>abounds in reminiscences, anecdotes, ironic asides, and fascinating case reports. Few books provide so much historic background, biographic data, and geographic settings. Where else can one find a professional note on Pick, an informative reference to Garcia, and a case report of pericarditis afflicting the Nobel laureate Finsen —all on the same page? The second edition is brought up to date by
Differential Ligand-Mediated Pituitary Somatostatin Receptor Subtype Signaling: Implications for Corticotroph Tumor Therapy
Authors: Anat Ben-Shlomo, Herbert Schmid, Kolja Wawrowsky, Oxana Pichurin, Erika Hubina, Vera Chesnokova, Ning-Ai Liu, Michael Culler, Shlomo Melmed
Journal: Endocrine Reviews (2009)

ObjectivePituitary targeted pharmacotherapy for Cushing’s disease is challenging and ineffective. Unlike octreotide and lanreotide, the multisomatostatin receptor (SST) analog pasireotide that exhibits SST5 greater than SST2 binding affinity offers potential for treating Cushing’s disease. Because corticotroph cells express SST5 more abundantly than SST2, pasireotide likely exerts superior corticotroph action mainly through SST5. However, there is no direct evidence for this assumption, and moreover, the ligand effect on corticotroph SST2 is not known.
Tuberculosis
Authors: Sarah Ringold, Cassio Lynm, Richard M. Glass
Journal: JAMA (2008)

TuberculosisT uberculosis (TB) is infection with Mycobacterium tuberculosis, a type of bacterium.Tuberculosis infection typically occurs after repeated or prolonged exposure to the coughing of an actively infected person.Persons with HIV infection are at particularly high risk.Infection can involve any organ in the body, but the lungs are the most common site of damage.In active infection, there is damage to organs.In latent infection, the person carries the bacteria but does not have current signs of active infection.Latent TB infection is important to diagnose and treat because it can become active infection.Multidrug-resistant TB is resistant to (cannot be killed by) standard antibiotics.This type of TB arises from improper or incomplete treatment of TB infection or through exposure to a person infected with this type of bacterium.The July 23/30, 2008, issue of JAMA includes 2 articles about tuberculosis.This Patient Page is based on one previously published in the June 8, 2005, issue of JAMA.
THE CORPUS LUTEUM AND THE UTERUS
Journal: JAMA (1923)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Social and Industrial Medicine
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Effects of treatment on morbidity in hypertension. II. Results in patients with diastolic blood pressure averaging 90 through 114 mm Hg
Journal: JAMA (1970)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Bullous Pemphigoid
Authors: Misha Rosenbach, Karolyn A. Wanat, Cassio Lynm
Journal: JAMA Dermatology (2013)

Bullous Pemphigoid Bullous pemphigoid is an autoimmune disease, which means that the cells in the body that normally fight infection attack the body instead.The body's immune system is confused and makes an antibody (type of protein used to fight infection) that targets a part of the skin that normally holds it together.The attack on the skin causes blisters (firm, fluid-filled bubbles on the skin) to form.This disease most often involves only the skin, but the eyes, mouth, and genitals also can be affected.In most cases, the disease develops on its own, but certain medications also can cause bullous pemphigoid to develop.Bullous pemphigoid commonly affects people older than 60 years but can occur in younger people.Once someone is diagnosed as having this disease, they can have it for many years.Treatment helps to control the disease, but there is no permanent cure.
Occasional use of marijuana
Authors: R. H. Schwartz
Journal: JAMA (1988)

<h3>In Reply. —</h3> In response to Dr Goldstein, our study was a comparison of the tolerability and lipid-lowering effects of lovastatin and cholestyramine, so that our conclusion that lovastatin is more effective than cholestyramine applies only to the effects of the two drugs on lipids and lipoproteins, in particular the primary variables total and low-density lipoprotein (LDL) cholesterol. On this basis, 40 mg of lovastatin twice a day was approximately twice as effective as 12 g of cholestyramine twice a day, producing mean reductions in total and LDL-cholesterol of 34% and 42%, respectively, compared with 17% and 23% for cholestyramine. We agree that the ultimate value of lipid-lowering agents should be based on their effects on artherosclerosis. Several clinical trials to examine the effects of lovastatin and the closely related simvastatin on coronary lesion progression and coronary event rates are under way or about to begin. Although the results of
The Mesangium of the Renal Glomerulus
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 1404: How Peripheral Cardiac Conduction Cells Adapt to Pressure Overload
Authors: Brett S Harris, Dimitri Scholz, Catalin F Baicu, Patrick Y Jay, Mary S Rackley, Terrence X O’Brien
Journal: Circulation (2007)

The ventricular peripheral conduction system (PCS) is composed of unique cardiomyocytes responsible in health for the coordinated contraction of every working cardiomyoctye. Although isolated PCS cells have been studied extensively, in vivo study has been limited by difficulties in identifying large numbers of PCS cells, making it unclear how the PCS responds to disease stimuli. Methods: To address the hypothesis of whether the PCS undergoes hypertrophy with pressure-overload, we employed a novel EGFP-Connexin40 knock-in transgenic mouse which specifically labels Cx40-expressing cells with enhanced green fluorescent protein (EGFP). The Cx40EGFP heterozygote mouse allows the visualization of the entire PCS at the macro and cellular level and, in previous work, has been shown to have a normal phenotype. We then surgically induced left ventricular hypertrophy (LVH) using transaortic constriction (TAC). Functional echocardiography confirmed LVH averaging a 94 % increase in LV/body weight after 4 weeks with preserved systolic function. Sacrifice confirmed an average 79% increased heart weight (similar to control TAC). Results: EGFP positive conduction cells measured in whole heart sections were smaller at baseline by 46% (p&lt;.001) in cross sectional area compared with working cardiomyocytes confirming published data on smaller conduction cell size. Most interestingly, EGFP positive PCS cells also underwent hypertrophy increasing by 30% (p&lt;.001) in response to load. Working cardiomyocytes increased in cell size by 42% (p&lt;.001) after TAC. Immunohistochemistry (IH) was used to confirm the identity of EGFP cells as conduction tissue. Additionally, IH showed a marked increase in expression of the cardiac transcription factor Nkx2–5 in PCS cells relative to working cells. Conclusions: We have shown for the first time that peripheral conduction system cardiomyocytes undergo hypertrophy with pressure-overload in a mouse model. In conjunction with our previous finding that Nkx2–5 increases with pressure-overload, this provides an initial characterization of PCS pathophysiology from a cellular perspective.
Author Index
Authors: Andrew Abreo, Acevedo Galvis, Atsuko Adachi, Yoko Adachi, Adams Adeli, Adelman Daniel, Adjei Stacey, N Adkinson, Charuta Agashe, Ariela Agress, Andrea Aguilera, Ahmad Hassan, Akaba Tomohiro, Akamatsu Taisuke, Akerman Meredith, Ozge Aktas, Al Mardini, Alao Hawwa, Rosario Alarcon, Alava Cruz, Caleb Alexander, Alexander Chandran, Maria Alfaro, Michelle Altrich, Sabine Altrichter, Alicia Alvarez, Kristin Alvarez, Jos Alvarez, Alvarez Arango, Joyti Angal, Carolina Antonietti, Yuji Aoki, Victoria Aparicio, Andrea Apter, Marcella Aquino, Irina Arnold, Anna Arroyo, Luisa Arruda, Arthur Ataam, Asada Kazuhiro, Amanda Atanasio, Dan Atkins, Adelle Atkinson, Pedro Avila, Maria Baeza, Yun Bai, Mary Baker, Susan Ball, Rachel Ballard, Ballesteros Benavides, Jeri Barak, Barba Alban, Colin Barber, Barilla Labarca, Maria Louise, Lisa Barker, Sierra Barone, Barra Castro, Laura Barrionuevo, Katherine Bartholomay, Marta Barzaga, Maureen Bauer, Rachel Baum, Sharon Baum, Rachel Baur, Joannie Bautista, Daniela Bayr, Bezditko Tetyana, Biagini Myers, Biswas Sarkar, Andrea Blackman, Jeffrey Blair, Blake Kathryn, Blanca Miguel, Blanca -Lopez, Blanca-L Opez, Bla Blanco, Melissa Borofsky, Magnus Borres, Matteo Borro, Nikita Bortnik, Nicole Brackett, Jessica Braid, Larissa Brandão, Joseph Braun, Emily Brigham, Broesby-Olsen Bronchick, Anna Bronoff, Helen Brough, Hannah Brown, Julie Brown, Pedro Bubach, Joshua Bublitz, Angelo Bucci, Natalie Buchinsky, Esteban Burchard, Lucrecia Bustamante, Melina Butuci, Teresa Caballero, Angelita Cabrera, Claudia Cabrera, Cabrera Quijada, Cabrero Manresa, Justine Calise, Carlos Camargo, Camejo Camargo, Cameron Malliany, Eugenio Capitle, Juan Carlos, Ricardo Cardona, Victoria Cardona, John Carlson, Rachel Carlson, Jeronimo Carnes
Journal: Journal of Allergy and Clinical Immunology (2020)
Migration of urbanites to small towns for medical care
Authors: G. E. Garrison
Journal: JAMA (1974)

In recent decades, the concentration of medical manpower and facilities in large metropolitan areas has paralleled the rapid urban centralization of most products and services in the United States. Predictably, people living in small towns and rural areas go to large cities for some of their medical services. However, it is generally not appreciated that physicians practicing in small towns spend a sizeable proportion of their time providing medical care to people who live in somewhat distant, large, metropolitan areas. Apparently, these urban citizens perceive the presence of a type of medical care in small towns that is more desirable than that provided in large cities.
The Public Service
Journal: JAMA (1906)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Book Review Breast Cancer (Atlas of Clinical Oncology.) Second edition. Edited by David J. Winchester, David P. Winchester, Clifford A. Hudis, and Larry Norton. 607 pp., illustrated, with CD-ROM. Hamilton, ON, Canada, BC Decker, 2006. $149.95. 1-55009-272-3 Textbook of Breast Cancer: A Clinical Guide to Therapy Third edition. Edited by Gianni Bonadonna, Gabriel N. Hortobagyi, and Pinuccia Valagussa. 411 pp., illustrated. Abingdon, England, Informa Healthcare/ Taylor &amp; Francis, 2006. $249.95…
Authors: Anne Moore
Journal: New England Journal of Medicine (2006)
Update: Influenza Activity—New York and United States, 1994-95 Season
Journal: JAMA (1995)

Influenza activity in the United States during the current influenza season began in the Northeast, and during late January, spread to other regions of the country. This report describes influenza outbreaks in nursing homes in New York and summarizes national influenza surveillance data from October 2, 1994, through February 11, 1995.
The Goulstonian Lectures ON DEATH BY ELECTRIC CURRENTS AND BY LIGHTNING: Delivered before the Royal College of Physicians of London
Authors: A. J. Jex-Blake
Journal: BMJ (1913)

drainage hlas already been dealt with by sulrgeons all over the world, as well as by myself, and those who have had a large experience in the operative treatment of these cases are arriving at definite conclusions as to the best mode of dealing with them.Chronic intestinal stasis is a subject that is growing very rapidly in importance, and it cannot be decided merely by conjecture or on previous ex- perience, but by the light of hard facts as afforded by the results of operative interference.
Salt content of kosher meat
Authors: S. M. Glick
Journal: JAMA (1985)

<h3>To the Editor.—</h3> We feel that the medical and scientific community should be aware of advertisements recently placed by tobacco interests in publications like<i>Newsweek, Time</i>, and the<i>Washington Post</i>. These ads interpret the results of the Multiple Risk Factor Intervention Trial (MRFIT) in such a way as to cast doubt on a causal relationship between smoking and coronary disease. The main "error" in the ad is to overlook the fact that the control group was "contaminated" (ie, a number of subjects in the control group altered their life-styles, including smoking behavior, without the extra special attention by the project staff). Thus, the study turned out to be a comparison between two methods of intervention and not between smoking and not smoking. Indeed, if one looks at those persons who actually<i>quit</i>and did not quit smoking in the groups who received and did not receive special attention by the
丝聚合蛋白降解产物和角层细胞表面纹理的季节性变化
Authors: K.A. Engebretsen, S. Kezic, C. Riethm€uller, J. Franz, I. Jakasa, A. Hedengran, A. Linneberg, J.D. Johansen, J.P. Thyssen
Journal: British Journal of Dermatology (2018)

在北方国家的冬季,湿疹风险会因为低温和低湿度而提高。湿疹会导致皮肤干燥、瘙痒和发炎,尤其常见于脸颊和手部等外部肌肤。近期,角层细胞表面的小突起(突出物)被发现与湿疹以及缺乏防止肌肤干燥的天然保湿因子(NMF)相关。这项来自丹麦的研究旨在调查季节对正常成人皮肤的NMF数量以及角层细胞表面突起的影响。在冬季和夏季,研究人员在80名健康志愿者(40名男性,40名女性;40名年龄为18≤40岁,40名年龄≥70岁)的脸颊和手部贴上胶带。也就是在皮肤上贴上胶带,然后撕下胶带,在显微镜下观察胶带。分析胶带上的NMF数量以及角层细胞表面纹理。与夏季相比,脸颊皮肤在冬季的NMF数量较少,角层细胞突起数量较多。与年轻参与者相比,年龄较大的参与者脸颊上的NMF数量较多。在夏季,患者自我表示接触紫外线较多与角层细胞表面突起数量增多有关。与夏季相比,手部皮肤在冬季的NMF数量较多,与男性参与者相比,女性参与者的NMF数量较多。因此,我们观察到季节对脸颊和手部NMF数量以及角层细胞表面纹理的影响。还发现了有关年龄和性别的差异,因此难以下定结论。我们的发现提供了解决皮肤干燥和皮炎季节性差异难题的又一个线索。