tbuckley/cabot-search huggingface dataset:
Editorial: Psychological sequelae of therapeutic abortion.
Journal: BMJ (1976)

A report is made on a study by H.S. Greer and his collaborators which is said to be the 1st study of the psychological sequelae of abortion since the 1968 British Abortion Act was passed. 360 women in consecutive series who were aborted in the first trimester by vacuum aspiration were studied. Compared with ratings before termination, significant improvement occurred in respect to psychiatric symptoms, guilt feelings, and interpersonal and sexual adjustment. Comparisons between those aborted and those refused abortions have shown little difference, although those refused may show a marginally greater frequency of sequelae. The most important elements in protecting a woman from psychological sequelae resulting from a decision either for or against termination are the care with which the decision is reached and the degree of support afterwards.
Pancreatitis, a Complication of Operation
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Childhood complications of nalidixic acid
Authors: E. E. Anderson
Journal: JAMA (1971)

A 5-year-old girl developed bilateral palsy of the sixth nerve and papilledema following administration of 43.5 gm of nalidixic acid over a 58-day period. The x-ray film of the skull, electroencephalogram, cerebral arteriogram, and ventriculogram were normal. When therapy with the drug was terminated, the papilledema rapidly resolved and lateral rectus function improved. Although nalidixic acid administration has been associated with increased intracranial pressure, to the best of our knowledge palsy of the sixth nerve and subsequent strabismus have not previously been described.
Human Disease Consequences of Fiber Exposures: A Review of Human Lung Pathology and Fiber Burden Data
Authors: Victor L. Roggli
Journal: Environmental Health Perspectives (1990)

Inhalation of asbestos fibers results in a variety of neoplastic and nonneoplastic diseases of the respiratory tract. Some of these diseases, such as asbestosis, generally occur after prolonged and intensive exposure to asbestos, whereas others, such as pleural mesothelioma, may occur following brief exposures. Inhalation of nonasbestiform mineral fibers can occur as well, and these fibers can be recovered from human lung tissue. Thus, there has been considerable interest in the relationship between mineral fiber content of the lung and various pathologic changes. Techniques for fiber analysis of human tissues have not been standardized, and consequently results may differ appreciably from one laboratory to another. In all reported series, extremely high fiber burdens are found in the lungs of individuals with asbestosis. Although there is a correlation between the tissue concentration of asbestos fibers and the severity of pulmonary fibrosis, further studies of the mineralogic correlates of fiber-induced pulmonary fibrosis are needed. Mesothelioma may occur with fiber burdens considerably less than those necessary to produce asbestosis. More information is needed regarding the migration of fibers to the pleura and the numbers, types, and dimensions of fibers that accumulate at that site. Patients with asbestosis have a markedly increased risk for lung cancer, but the risk of lung cancer attributable to asbestos in exposed workers without asbestosis who also smoke is controversial. Combined epidemiologic-mineralogic studies of a well-defined cohort are needed to resolve this issue. In addition, more information is needed regarding the potential role of nonasbestos mineral fibers in the pathogenesis of lung cancer.
Association News
Journal: JAMA (1923)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Loving Her
Authors: Lawrence J. Hergott
Journal: Annals of Internal Medicine (2015)

Ad Libitum7 July 2015Loving HerLawrence J. Hergott, MDLawrence J. Hergott, MDFrom Center for Bioethics and Humanities, University of Colorado School of Medicine, Denver, Colorado.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/M15-0536 Audio Reading - “Loving Her” Audio. Michael A. LaCombe, MD, Annals Associate Editor, reads "Loving Her," by L.J. Hergott. Your browser does not support the audio element. Audio player progress bar Step backward in current audio track Play current audio trackPause current audio track Step forward in current audio track Mute current audio trackUnmute current audio track 00:00/ SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail I had a patient who,for yearsafter his wife of many yearsdied,went to her grave daily.He didn't go there to visit herand then get on with his day.Visiting her was his day,and he spent it sitting in a chairnear her,or what was left of her,in the groundand in his heart.He must have spoken to herthroughout the day—would that be monologue or soliloquy?I'm sure to him it was a conversation.Why did he do it?I never asked,perhaps assuming I understood.Whatever his reasons,he described his days contentedly.Clinical concerns aside,loving you as I do,I was happy for him.Lawrence J. Hergott, ... Author, Article, and Disclosure InformationAffiliations: From Center for Bioethics and Humanities, University of Colorado School of Medicine, Denver, Colorado.Current Author Address: Lawrence J. Hergott, MD; e-mail, [email protected]net. PreviousarticleNextarticle Advertisement Audio Reading - “Loving Her” Audio. Michael A. LaCombe, MD, Annals Associate Editor, reads "Loving Her," by L.J. Hergott. Your browser does not support the audio element. Audio player progress bar Step backward in current audio track Play current audio trackPause current audio track Step forward in current audio track Mute current audio trackUnmute current audio track 00:00/ FiguresReferencesRelatedDetails Metrics 7 July 2015Volume 163, Issue 1Page: 51KeywordsHeart ePublished: 7 July 2015 Issue Published: 7 July 2015 Copyright & PermissionsCopyright © 2015 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Manual of Organic Materia Medica and Pharmacognosy. An Introduction to the Study of the Vegetable Kingdom and the Vegetable and Animal Drugs. Comprising the Botanical and Physical Characteristics, Source, Constituents, Pharmacopeial Preparations, Insects Injuries to Drugs, and Pharmacal Botany.
Journal: JAMA (1900)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Anatomische Grundlagen
Authors: Reinhard Rossdeutscher
Journal: Thorax (2003)

Das Kapitel stellt in einer Beschreibung der systematischen und z. T. der topographischen Anatomie der Atmungsorgane zunächst das Lungenparenchym und die Atemwege im makroskopischen und mikroskopischen Aufbau vor. Es folgt eine Darstellung der Hilusanatomie und der im Hilus verlaufenden Gefäße, des Lymphsystems und der Innervation von Lungenparenchym und Atemwegen (Abschn.2.1).
LUKE THE PHYSICIAN.
Journal: JAMA (1907)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
B-cell immunodeficiency in acquired immune deficiency syndrome
Authors: A. J. Ammann
Journal: JAMA (1984)

To investigate B-cell function in acquired immune deficiency syndrome (AIDS), we immunized a group of patients with AIDS with pneumococcal polysaccharide (tetradecavalent) and protein (keyhole-limpet hemocyanin) antigens. Antibody responses were determined three to four weeks after immunization. Compared with controls, patients with AIDS had significantly lower geometric mean antibody levels to polysaccharide before and after immunization. Levels before and after immunization were frequently below a level thought to correlate with protection. Patients with AIDS also had a significant reduction in their primary antibody response to the protein antigens. The results of these studies indicate that AIDS is associated with an acquired B-cell as well as T-cell immunodeficiency. It is suggested that future studies should consider the evaluation of passive antibody in the prevention of infection and/or prevention of progressive immunodeficiency. (<i>JAMA</i>1984;251:1447-1449)
Long-term quality of life and neuropsychologic functioning for patients with CNS germ-cell tumors: From the First International CNS Germ-Cell Tumor Study
Authors: Stephen A. Sands, Stewart J. Kellie, Amy L. Davidow, Blanca Diez, Judith Villablanca, Howard L. Weiner, Maria C. Pietanza, Casilda Balmaceda, Jonathan L. Finlay
Journal: Neuro-Oncology (2001)

This study evaluated the quality of life and neuropsychologic functioning among patients enrolled between 1989 and 1993 in the First International CNS Germ-Cell Tumor Study.Quality-of-life questionnaires (Short Form-36 or Child Health Questionnaire) were completed on 43 patients at median follow-up of 6.1 years after diagnosis (range, 4.5-8.8years), and intellectual and academic testing was performed on 22 patients.Psychosocial and physical functioning of patients aged 19 years and older at follow-up was within the average range, whereas the same functioning for patients aged 18 years and younger, as reported by their parents at follow-up, was low average and borderline, respectively.Overall psychosocial and physical health summary scores were positively correlated with age at diagnosis for both groups combined.Those who received CNS radiation therapy (n = 29) reported signi cantly worse physical health, but similar psychosocial health, compared with those treated without radiation.Neuropsychologic testing indicated full-scale and verbal IQ, reading, spelling, and math skills in the average range, and performance IQ in the low average range.Intelligence and math skills were positively correlated with age at diagnosis.Those with germinomas signi cantly outperformed those with nongerminomatous/ mixed tumors on all neuropsychological measures administered.Younger patients diagnosed with CNS germ-cell tumors are at increased risk for psychosocial and physical problems as well as neuropsychologic de cits.Exposure to irradiation adversely affects overall physical functioning, whereas tumor pathology appears to be a salient neurocognitive risk factor.Collaborative and randomized studies are required to further elucidate the late effects arising from factors such as age at diagnosis, tumor histology, level of irradiation therapy, and chemotherapy toxicity among these young and potentially curable patients.
The health care mess. A bit of history
Authors: J. B. Richmond
Journal: JAMA (1995)

THERE is general agreement that both the financing and the organization of US health care services are a mess. The public image is that confusion, complexity, and contradictions arise because earlier health policies did not work to accomplish their goals. Yet, an examination of how what has been termed a "mess" developed, as well as the nature and dimensions of the mess, reminds us that the public image of health policy is at variance with the historical record. It is important to understand that health policies<i>did</i>work. Those who ignore or misinterpret history and are skeptical that policies can be effective are wrong. <h3>BACKGROUND</h3> In the period following World War II our health policies worked extraordinarily well. They resulted in a number of spectacular successes. For example, we faced a shortage of health care personnel, a deficiency of acute care general hospital beds, and a relatively low level of
The Kidney
Authors: Gilbert M. Eisner
Journal: JAMA (1974)

In his preface the author states that he has tried "to convey a personal view of a nephrophile, who has spent the past 35 years of his life with the kidney." He has succeeded in this goal and turned out an admirable piece of work. This is a scholarly work that differs from many texts in two important aspects. There is a historical perspective which is often of considerable interest, and, in cases of conflicting data, the author usually leaves no doubt about his own interpretation and does not hesitate to point out the shortcomings in many studies and reports. The book actually combines a text of physiology and a text of clinical nephrology. The first third of the volume is devoted to physiology. In the subsequent clinical sections the diseases are examined in terms of the altered physiology, and the approaches to treatment are also based on physiologic principles.
Observations on Scurvy as It Was Developed in Bath and Its Neighbourhood, in the Spring of 1847
Authors: J. Barrett
Journal: BMJ (1849)

OBSERVATIONS ON SCURVY.173 extend over several years, with occasional amendments, followed bv relapses upon any deraugement of the general health.They may terminate either by the occurrence of a low form of inflammation,attacking some important organ to which the condition of the ,blood seems to afford much predisposition, or more gradually, with increasing dropsical distension, oppressive dyspncea, and a soporose or comatose state, before the fatal event.The reports of this institution would furnish many cases of this kind, but I have not taken one for consideration, as the progress of such ,cases, till approaching dissolution, are verv similar to tbat last mentioned.
A randomized, controlled trial of a 24-month course of interferon alfa 2b in patients with chronic hepatitis B who had hepatitis B virus DNA without hepatitis B e antigen in serum
Authors: P Lampertico
Journal: Hepatology (1997)

Short-term interferon treatment of serum hepatitis B e antigen (HBeAg)-negative carriers with serum hepatitis B virus (HBV) DNA and histological features of chronic hepatitis B has been largely unsuccessful. In a pilot study of long-term treatment, 42 such patients were randomly assigned to 6 million units of interferon alfa 2b (IFN-α2b) three times per week for 24 consecutive months (n = 21, 4 with cirrhosis) or to no therapy (n = 21, 3 with cirrhosis). Five patients (24%) discontinued therapy because of treatment-related adverse reactions. Serum levels of alanine transaminase (ALT) became persistently normal and HBV DNA undetectable by dot-blot assay in 8 patients receiving interferon and in 2 untreated controls (38% vs. 10%; P = .03). Hepatitis flare-ups disappeared in 17 patients during therapy compared with 6 controls (81% vs. 29%; P < .001). During a median period of 22 months after interferon was stopped, 2 treated patients (10%) lost serum hepatitis B surface antigen (HBsAg) and seroconverted to antibodies to hepatitis B surface antigen (anti-HBs). Serum ALT remained persistently normal and HBV DNA undetectable by dot-blot assay in 6 initial responders and 1 initial nonresponder, compared with none of the 21 untreated controls (sustained response: 33% vs. 0; P < .001). Comparative analysis of pre- and posttreatment liver biopsies showed that mean Knodell scores dropped in the treated group (10.3 to 5.3; P = .01), but not in the untreated group (9.3 to 9.8; not significant). In conclusion, a 24-month course of treatment with 6 MU IFN-α2b was well tolerated by most patients, led to sustained suppression of HBV in one third, and attenuated hepatitis in 81% of patients.
Editorial Board, Contents, Forthcoming articles
Authors: Steven Laureys, Alex Holcombe, Colin Clifford, David Eagleman, Pooya Pakarian, Timothy Andrews, Dale Purves, William Simpson, Rufin Vanrullen, Kathleen Mcdermott, Karl Szpunar, Clive Wynne, Ian Apperly, Dana Samson, Glyn Humphreys, Stefan Koelsch, Walter Siebel, Patrik Vuilleumier, Julian Ogilvie, Katie Forsythe, Manager Moulton
Journal: Trends in Cognitive Sciences (2005)
Combination Therapy with Ofatumumab and Lenalidomide in Patients with Relapsed Chronic Lymphocytic Leukemia (CLL): Results of a Phase II Trial
Authors: Alessandra Ferrajoli, Susan O'Brien, William G. Wierda, Stefan Faderl, Xavier Badoux, Zeev Estrov, Ellen Schlette, Susan C. Smith, Ana B. Ayala, Lorenzo Falchi, Steliana Calin, Hagop M. Kantarjian, Michael J Keating
Journal: Blood (2011)
Poster Discussions
Authors: F. Fourrier, B. Duvivier, M. Roussel-Delvallez, H. Boutigny, M. Jourdain, J. L. Auffray, A. P. Forget, C. Chopin, I. Mahé, G. Martin, F. Dhalluin, K. Crowley, J. Twomey, L. Fenelon, Lessire Henry, Denis Benoit, Weyers Philippe, Vankeerberghen Luc, R. Prat, J. Gardeñas, J. Oliver, J. Rello, J. Vallés, C. Royo
Journal: Intensive Care Medicine (1996)
Gastropatías de Origen Renal.
Journal: JAMA (1924)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Diffuse panbronchiolitis
Authors: V. Poletti, G. Casoni, M. Chilosi, M. Zompatori
Journal: European Respiratory Journal (2006)

Diffuse panbronchiolitis (DPB) is an idiopathic inflammatory disease, well recognised in Japan and principally affecting the respiratory bronchioles, causing a progressive suppurative and severe obstructive respiratory disorder. If left untreated, DPB progresses to bronchiectasis, respiratory failure and death. It was first described in the early 1960s. Subsequently, in 1969, the disease was named DPB to distinguish it from chronic bronchitis. “Diffuse” refers to the distribution of the lesions throughout both lungs, and “pan-” refers to the involvement of inflammation in all layers of the respiratory bronchioles. The distinctive imaging and histological features, the coexisting sinusitis, and the isolation of Haemophilus influenzae and Pseudomonas aeruginosa in the sputum enhance disease recognition. Histologically, DPB is characterised by chronic inflammation, localised mainly in the respiratory bronchioles and adjacent centrilobular regions, with characteristic interstitial accumulation of foamy histiocytes, neutrophils and lymphocyte infiltration. Neutrophils and T-lymphocytes, particularly CD8+ cells, together with the cytokines interleukin-8 and macrophage inflammatory protein-1, are believed to play key roles in the development of DPB. A significant improvement in the prognosis of this potentially fatal disease has been recently reported thanks to the use of long-term therapy with macrolide antibiotics, the effect of which is attributed to an anti-inflammatory and immunoregulatory action.