EXPERIMENTAL DIABETES
Authors: MILTON S. SACKS
Journal: Annals of Internal Medicine (1950)

Editorial1 March 1950EXPERIMENTAL DIABETESMILTON S. SACKSMILTON S. SACKSSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-32-3-572 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptComplete extirpation of the dog pancreas by Minkowski and von Mering1in 1889 may be viewed as the first approach to the production of experimental diabetes. It was this fundamental experiment which led, 33 years later, to the isolation of insulin by Banting and Best.2Since 1922 further elucidation of the complexities of carbohydrate metabolism has been achieved by physiological experimentation. Numerous studies have led to the knowledge that the metabolic activity of these foodstuffs is not solely under the control of the beta cell hormone of the pancreas, but involves regulatory activities of other endocrine glands. 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CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDrugs and pharmaceuticals: management of intoxication and antidotesOccurrence of Hepatic Fibrosis in Children with Acute Leukaemia Treated with Folic Acid AntagonistsMethotrexateAdvances in Chemotherapy of Cancer in ManClinical studies on anticancer agents from 1949 to 1951TREATMENT OF ACUTE LEUKÆMIA WITH AMINOPTERINTreatment of Acute Leukæmia 1 March 1950Volume 32, Issue 3Page: 572-576KeywordsCarbohydrate metabolismEndocrine physiologyHormonesInsulinPancreas Issue Published: 1 March 1950 PDF downloadLoading ...