tbuckley/cabot-search huggingface dataset:
The process of peer review of scientific manuscripts
Authors: E. Williams
Journal: JAMA (1988)

Much has been said and written about the peer review process for scientific journals. A simple search of the MEDIS database reveals 435 articles that contain the term "peer review." The first International Congress on Peer Review in Biomedical Publication, sponsored by the American Medical Association and to be held in 1989 in Chicago,<sup>1</sup>will delve into the effectiveness of this process extensively. But there is another side to the peer review process. The administration of a peer review file and its daily use for reviewing manuscripts is complicated.<sup>2</sup>Management of such a large body of data has been made somewhat easier through computerization. Our peer reviewer file and manuscript processing procedures were converted from paper to electronics in 1988 through a difficult and tedious process. The file of nearly 6000 reviewer names, addresses, and relevant information is now available on a computer database. When a manuscript arrives
Abortion and the Doctor
Authors: J. R. E.
Journal: Annals of Internal Medicine (1967)

Editorials1 November 1967Abortion and the DoctorJ. R. E.J. R. E.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-67-5-1111 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptUnder what circumstances and for what reasons should a doctor deliberately interrupt a pregnancy and thus arrest the beginning of a new human life? This has always been a serious question for the medical profession and for society. Society through its laws has strictly prescribed the indications for abortion, and churches of the Western world have taken definite stands on the issue. Yet the question is now being raised with increasing frequency and with a sense of urgent need to find more satisfactory answers.This urgency is evident from the flood of books and articles in the lay press as...References1. CALDERONE M (editor): Abortion in the United States. Hoeber Medical Division, Harper & Row, Inc., New York, 1958. CrossrefGoogle Scholar2. GUTTMACHER AF (editor): The Case for Legalized Abortion. Diablo Press, Berkeley, 1967. Google Scholar3. SMITH DT: Abortion and the Law. Western Reserve University Press, Cleveland, 1967. Google Scholar4. OBER WB: We should legalize abortions. Saturday Eve. Post, p. 14, Oct. 8, 1966. Google Scholar5. LADER L: Abortion. The Bobbs-Merrill Co., Inc., Indianapolis, 1967. Google Scholar6. NEUHAUSPLEASANTSWASSMERHELLEGERS RJJTHE: Abortion beyond assumptions. Commonweal 86: 408, 1967. Google Scholar7. HELLEGERS HE: Abortion, the law, and the common good. Med. Opinion Rev. 3: 76, (May) 1967. Google Scholar8. NOVAK M: Abortion is not enough. Christian Century, p. 431, April 5, 1967. Google Scholar9. AMA policy in therapeutic abortion. JAMA 201: 544, 1967. CrossrefGoogle Scholar10. NISWANDERKLEINRANDALL KRMCL: Changing attitudes toward therapeutic abortion. JAMA 196: 1140, 1966. CrossrefMedlineGoogle Scholar11. Abortion: the doctor's dilemma. Modern Med. p. 12, April 24, 1967. Google Scholar12. LEDERBERG J: A geneticist looks at contraception and abortion, in The Changing Mores of Biomedical Research, Supplement 7, Part II. Ann. Intern. Med. 67: (Sept.) 1967. MedlineGoogle Scholar13. MEDAWAR PD: Discussion. Ibid., p. 61. Google Scholar14. HARDIN G: Blueprints, DNA, and abortion: a scientific and ethical analysis. Med. Opinion Rev. 3: 74, (Feb.) 1967. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byIn Memoriam: J. Russell Elkinton, MD, MACP, FRCP(L); 1910–2002; Editor, Annals of Internal Medicine, 1960–1971Edward J. Huth, MD, Editor EmeritusJ. Russell Elkinton, M.D., M.A.C.P.: A TributeMARSHALL N. FULTON, M.D. 1 November 1967Volume 67, Issue 5Page: 1111-1113KeywordsPregnancy ePublished: 1 December 2008 Issue Published: 1 November 1967 PDF downloadLoading ...
Fatal Cases of Rocky Mountain Spotted Fever in Family Clusters—Three States, 2003
Journal: JAMA (2004)

Rocky Mountain spotted fever (RMSF), a tickborne infection caused by Rickettsia rickettsii and characterized by a rash, has a case-fatality rate as high as 30% in certain untreated patients. Even with treatment, hospitalization rates of 72% and case-fatality rates of 4% have been reported. This report summarizes the clinical course of three fatal cases of RMSF in children and related illness in family members during the summer of 2003. These cases underscore the importance of 1) prompt diagnosis and appropriate antimicrobial therapy in patients with RMSF to prevent deaths and 2) consideration of RMSF as a diagnosis in family members and contacts who have febrile illness and share environmental exposures with the patient.
QuickStats: Percentage* of Visits by Patients Aged ≥18 Years to Office-Based Physicians† Made by Patients with ≥2 Selected Diagnosed Chronic Conditions,§ by Physician Specialty Category and Patient Age Group — National Ambulatory Medical Care Survey, 2015
Journal: MMWR Morbidity and Mortality Weekly Report (2017)

In 2015, the percentage of office-based physician visits by adults with two or more diagnosed chronic conditions was 53.1% for primary care physicians, 38.5% for medical specialists, and 23.9% for surgeons. This pattern was observed for each of the age groups studied. The percentage of visits increased with age group, regardless of specialty category.
P-136 De novo malignancy after living donor liver transplantation
Authors: M. Shinoda, O. Itano, H. Obara, M. Kitagoo, T. Hibi, Y. Abe, H. Yagi, K. Matsubara, Y. Yamada, A. Fujino, K. Hoshino, T. Kuroda, Y. Kitagawa
Journal: Annals of Oncology (2015)
Differential Ligand-Mediated Pituitary Somatostatin Receptor Subtype Signaling: Implications for Corticotroph Tumor Therapy
Authors: Anat Ben-Shlomo, Herbert Schmid, Kolja Wawrowsky, Oxana Pichurin, Erika Hubina, Vera Chesnokova, Ning-Ai Liu, Michael Culler, Shlomo Melmed
Journal: Endocrine Reviews (2009)

Pituitary targeted pharmacotherapy for Cushing’s disease is challenging and ineffective. Unlike octreotide and lanreotide, the multisomatostatin receptor (SST) analog pasireotide that exhibits SST5 greater than SST2 binding affinity offers potential for treating Cushing’s disease. Because corticotroph cells express SST5 more abundantly than SST2, pasireotide likely exerts superior corticotroph action mainly through SST5. However, there is no direct evidence for this assumption, and moreover, the ligand effect on corticotroph SST2 is not known. We used AtT20 mouse pituitary corticotroph tumor cells stably overexpressing SST2 or SST5 and TtT/GF mouse pituitary folliculostellate cells stably or transiently expressing SST receptors to examine ligand-receptor activation by SST2- and SST5-selective agonists. We show that pasireotide was more potent than either octreotide or somatostatin-14 in mouse corticotroph cells. Pasireotide potency is not affected by SST2 abundance, SST2 antagonist treatment, or octreotide cotreatment in SST2-overexpressing cells. Pasireotide also does not induce SST2 internalization and attenuates octreotide or SRIF14-induced SST2 internalization only at superphysiological dose ranges. In contrast, octreotide attenuates pasireotide potency in SST5-overexpressing cells. Moreover, short exposure to pasireotide causes prolonged inhibition of forskolin or CRH-induced cAMP accumulation, in contrast to somatostatin-14- and SST2-selective agonists that induced postwithdrawal cAMP rebound. Long-term pasireotide signaling effects are enhanced by SST5 overexpression. The results indicate that SST5 determines short- and long-term enhanced pasireotide action in corticotroph cells, whereas the ligand action on SST2 is negligible.
Editorial: Megacolon.
Journal: BMJ (1975)

earlier had not been made available or for other reasons.Clearly this is a highly unsatisfactory state of affairs-several of the colours for which no A.D.I.s were given are still being used in food.Some addition of chemicals to food to preserve it and to enable it to be distributed in suitable processed forms is unavoidable.But only a fine line separates the use of chemicals for these reasons and the unnecessary adulteration of food for no reason other than profit.Laboratory tests and regulatory committees go a long way to ensuring that we come to no harm from chemicals added to food, but no system of safeguards merits absolute confidence, and if we mind our bellies very studiously and very carefully we will eschew all unnecessary adulteration of food.We can make a start by eliminating synthetic food colours.
Culpability and accountability of hospitalized injured alcohol-impaired drivers. A prospective study
Authors: K. I. Maull
Journal: JAMA (1984)

During the three-year period ending October 1982, driver records, crash reports, and blood alcohol concentrations were correlated for 56 alcohol-impaired drivers injured seriously enough to warrant hospital admission. Blood alcohol concentration levels exceeded 0.15 vol% in all patients. Despite a high level of suspicion of alcohol involvement and assessment of culpability by the law enforcement officer at the scene, there were no convictions for driving under the influence of alcohol (DUI) among this problem-drinker population. Injury seems to offer additional protection from enforcement of DUI statutes and, if the patient survives his injuries, allows the offender to resume driving without interdiction. (<i>JAMA</i>1984;252:1880-1883)
Correction
Journal: BMJ (1954)

In short, the use of ultraviolet irradiation is tending to be co,nfined to dermatology, in which it is found of value in various skin conditions.If vitamin D is needed it is far quicker to give it by mouth than to elaborate it slowly in the skin by means of ultraviolet irradiation.There is no evidence that the deposition of melanin in the skin is in any way harmful. Chrysanthemum SensitivityQ.-A nurserynwii is sensitive to chrysanthemums, con- tact with blooms and leaves producing an intense skin irritation.The juice does not seem to be irritant, as, for example, when taking chrysanthemnum cuttings.Local applications of antihistamines help slightly.Barrier creams are not
Cereport® (RMP-7) increases carboplatin levels in brain tumors after pretreatment with dexamethasone
Authors: Reginald L. Dean, Dwaine F. Emerich, Brant P. Hasler, Raymond T. Bartus
Journal: Neuro-Oncology (1999)

Accumulating evidence suggests that dexamethasone might decrease permeability of the blood-brain tumor barrier, further limiting the delivery of agents into brain tumors.The bradykinin B 2 receptor agonist, Cereport ® (RMP-7), selectively increases permeability of the vasculature supplying brain tumors in both animal models and humans.The present study was conducted to characterize the effects of dexamethasone on the blood-brain tumor barrier and its potential interaction with Cereport's ability to enhance penetration of radiolabeled carboplatin.Dexamethasone (1.5 mg/kg/day, twice a day) was given to RG2 glioma-bearing rats via oral gavage for 3 consecutive days.After treatment, animals received a 15-min intracarotid infusion of Cereport (4.5 µg/kg) and a bolus of [ 14 C]carboplatin.The levels of [ 14 C]carboplatin (nCi/g) in the tumor and nontumor regions were determined at 1, 14, or 24 h after the last dose of dexamethasone.Dexamethasone, alone, significantly decreased the levels of radiolabeled carboplatin permeating the tumor (19%), although there were no signi cant differences between any of the time points examined.Cereport administration signi cantly increased levels of carboplatin in the tumor, independent of whether or not dexamethasone was given (46% with and 49% without).Although the relative effects of Cereport on tumor carboplatin levels were not affected by dexamethasone, the absolute levels achieved with Cereport were modestly reduced (44 nCi/g versus 55.5 nCi/g of [ 14 C]carboplatin, with and without dexamethasone, respectively).Thus, while the data support the use of Cereport as adjunctive therapy in the treatment of glioma patients, they also warn that the use of dexamethasone may reduce delivery of chemotherapeutic agents to brain tumors, even when special pharmacologic measures are employed to enhance delivery.
The influence of ultraviolet radiation on allergic contact dermatitis in the guinea-pig. II. Psoralen/UVA radiation
Authors: WARWICK L. MORISON, JOHN A. PARRISH, MICHAEL E. WOEHLER, KURT J. BLOCH
Journal: British Journal of Dermatology (1981)

Journal Article The influence of ultraviolet radiation on allergic contact dermatitis in the guinea‐pig. II. Psoralen/UVA radiation Get access WARWICK L. MORISON, WARWICK L. MORISON Department of Dermatology, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts 02114, U.S.A. Search for other works by this author on: Oxford Academic Google Scholar JOHN A. PARRISH, JOHN A. PARRISH Department of Dermatology, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts 02114, U.S.A. Search for other works by this author on: Oxford Academic Google Scholar MICHAEL E. WOEHLER, MICHAEL E. WOEHLER GTE Laboratories, Inc., Waltham, Massachusetts 02154, U.S.A. Search for other works by this author on: Oxford Academic Google Scholar KURT J. BLOCH KURT J. BLOCH Clinical Immunology and Allergy Units of the Medical Services, Massachusetts General Hospital, Boston, U.S.A. Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 104, Issue 2, 1 February 1981, Pages 165–168, https://doi.org/10.1111/j.1365-2133.1981.tb00040.x Published: 01 February 1981 Article history Accepted: 25 April 1980 Published: 01 February 1981
Subtotal Parathyroidectomy in Azotemic Renal Osteodystrophy
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Booknote
Journal: JAMA (1991)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Malingering.
Authors: Murray Galt Motter
Journal: JAMA (1898)

Washington, D. C., Aug. 24, 1898. <h3>To the Editor:</h3> —Apropos of the communication on "Malingering" (p. 423, August 20), suits for alleged malpractice are indeed to be deprecated, and it behooves the profession everywhere to stand together in resisting the attacks of the ignorant and the malicious, whether they be directly from the laity or, as is so often the case, inspired by more or less unprincipled and over-zealous "shysters" of the legal profession. On the other hand, when, as in the case cited, the medical practitioner adopts such questionable methods, does he not but reap the penalty of his folly? That a physician should consent "nearly every day, to make some kind of an application to the uterus" of a pronouncedly hysteric woman of neurotic history, "more to satisfy her than for any good it did," is of the very essence of charlatanry. There seems to have been no
The Gazette Pocket Speller and Definer.
Journal: JAMA (1904)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Effects of Estrogen-Only Treatment in Postmenopausal Women
Authors: Valerie Beral, Emily Banks, Gillian Reeves
Journal: JAMA (2004)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2022 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Evaluation of ibuprofen (Motrin). A new antirheumatic agent
Authors: J. R. Lewis
Journal: JAMA (1975)

Ibuprofen is a new, mild analgesic agent that may be useful in the symptomatic treatment of rheumatoid arthritis and osteoarthritis. Results of clinical studies have shown that its beneficial effects in these conditions are comparable, but not superior, to those of aspirin. However, at recommended doses it has less anti-inflammatory effect than aspirin. Its usefulness as an analgesic in the treatment of other types of pain and as an antipyretic has not yet been established. Ibuprofen causes fewer adverse effects on the gastrointestinal system, including occult bleeding, than aspirin. Serious adverse reactions have not been reported. Thus, ibuprofen may be acceptable for use in patients who cannot tolerate aspirin or other antirheumatic drugs. (<i>JAMA</i>233:364-365, 1975)
Rounds
Authors: Sasha K. Shillcutt
Journal: JAMA (2018)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Correction: Rural population mixing and childhood leukaemia: effects of the North Sea oil industry in Scotland, including the area near Dounreay nuclear site
Journal: BMJ (1993)

Public health implications * Vitamin K prophylaxis to the newborn is beneficial in preventing early and late haemorrhagic disease * Recent epidemiological studies indicated that intramuscular vitamin K prophylaxis doubled the risk for childhood cancer * In this study all Swedish infants born full term after non-instrumental delivery during 1973-89 were followed up for cancer until 1992 * No increase in risk of childhood cancer or childhood leukaemia was found with intramuscular vitamin K prophylaxis
Thank You and Welcome
Authors: E.J. H.
Journal: Annals of Internal Medicine (1972)

Editorials1 January 1972Thank You and WelcomeE.J. H.E.J. H.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-76-1-135_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe qualities of this journal are determined largely by the authors who send us their papers, the manuscript reviewers who provide us with critical judgements on what papers to publish, the editors who turn these judgements into decisions, and the Editorial Board who guide the editors with expert opinion.In the year 1 November 1970 through 29 October 1971, over 580 men and women in the United States and abroad read manuscripts for us. They assessed the potential importance of the submitted papers for the readers of this journal and prepared recommendations for revisions that would improve the clarity and... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 January 1972Volume 76, Issue 1Page: 135-135 Issue Published: 1 January 1972 PDF downloadLoading ...