tbuckley/cabot-search huggingface dataset:
Abstracts for the Society of Nuclear Medicine and Molecular Imaging, Greater New York and New England Chapters, 27th Annual Northeast Regional Scientific Meeting, Mystic, CT
Journal: Clinical Nuclear Medicine (2014)

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Pseudotachycardia in Holter monitoring. The potential for concealed bradycardia
Authors: W. B. Harden
Journal: JAMA (1981)

A pseudotachycardia was produced by a worn motor in a Holter recorder. This malfunction concealed an extreme bradycardia that was identified by simultaneous telemetry monitoring. Shortly thereafter, two other recorders purchased at the same time developed motor wear. In two of the three cases, motor failure was indicated by recorder noises. The artifactual nature of the pseudotachycardia was identified by the intermittent loss of voltage and compression of the ECG complexes in time that occurred during these intervals. Unrecognized artifacts in Holter monitor recordings may have serious adverse effects on both diagnosis and treatment. Potential causes of pseudoarrhythmia and methods for prevention and identification are reviewed. (<i>JAMA</i>1981;245:2427-2428)
Biliary ERCP
Authors: J.-M. Dumonceau
Journal: Endoscopy (2007)

In a cohort study of > 400 000 patients who underwent endoscopic retrograde cholangiopancreatography (ERCP) in the USA between 1988 and 2002 [1], Mazen Jamal et al. showed that the overall number of ERCPs decreased by 20 % between 1996 and 1998. This sudden reduction occurred after a period of linear increase (+ 200 % in 7 years), and was followed by a stabilization. Interestingly, a steady increase in the absolute numbers of procedures was recorded over the period 1988 - 2002 for two categories of ERCP, namely ERCP with a therapeutic goal (+ 200 %) and those carried out in patients older than 40 years (+ 60 %). The most evident explanations for these variations include a wider access to technologies that compete with diagnostic ERCP, and the introduction of laparoscopic cholecystectomy with a subsequent increase in the number of cholecystectomies (extraction of common bile duct [CBD] stones was the main indication for therapeutic ERCP) [2].
HOSPITAL SERVICE IN THE UNITED STATES
Journal: JAMA (1927)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
P14.01 A prospective multicenter single-arm clinical trial of bevacizumab for patients with surgically untreatable symptomatic brain radiation necrosis
Authors: S. Miyatake, M. Furuse, N. Nonoguchi, T. Kuroiwa, E. Nakatani, S. Kurisu, Y. Nakagawa
Journal: Neuro-Oncology (2016)
ABC of healthy travel. Immunisation--I.
Authors: E Walker, G Williams
Journal: BMJ (1983)

Compulsory: yellow I g~~~~~~A rrTravellers are at increased risk of infection from both unfamiliar I. korganisms and new strains of familiar organisms.Furthermore, contact with these organisms is increased through food and water contamination, biting arthropods, and increased human contact of varying intimacy.The likelihood of contracting any infection can be only crudely estimated and is related to (a) the countries visited, (b) the mode of travel and lifestyle, and (c) the length of stay.The likelihood of developing an illness after contact with certain organisms, usually those causing severe illness,
Simplifying the Application Process
Journal: JAMA (1991)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Medicolegal
Journal: JAMA (1907)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
ABC of preterm birth: Immediate care of the preterm infant
Journal: BMJ (2004)

ConclusionsOur findings confirm advancing paternal age as a strong independent risk factor for schizophrenia and indicate that 15.5% of cases of schizophrenia in our cohort could be due to the patient having a father who was aged > 30 years at birth.We found a stronger association in subjects without a family history of schizophrenia, providing further evidence to support the theory that accumulating de novo mutations in the germ cells of older fathers might contribute to an increased risk of schizophrenia in their offspring.In England and Wales the average paternal age has increased from 29.2 years in 1980 to 32.1 in 2002. 20 Assuming a background annual incidence rate for schizophrenia of 10/100 000 21 and that the association is causal, our results suggest that the increase in paternal age since 1980 could account for 710 out of the 6633 new cases of schizophrenia diagnosed in the United Kingdom in 2002.
Hydrotherapy
Authors: J. W. Cockerham
Journal: BMJ (1911)

BRITISpatients benefit is derived from all the resouroes of a spa, but in proportions not capable of definition.But it must be added, and with equal emphasis, that there is a third and a very large group in which the strictly balneological procedures constitute the primary and preponderating factors necessary for successfuil treatment.-Weare, etc.,
Cardiology Notebook for Preliminary Instruction in Medical Curricula.
Journal: Annals of Internal Medicine (1956)

This British manual has collected quantitative tests for drugs, not only from the British Pharmacopoeia and the British Pharmaceutical Codex, but also from many scientific periodicals and nonofficial texts such as Analytical Chemistry, Journal of the American Pharmaceutical Association, American Journal of Pharmacy, Apotheker-Zeitung, Archiv fur Pharmazie, Journal of Pharmacy and Pharmacology, etc.There is no chapter arrangement, as in most scientific books, but the first 523 pages are devoted to quantitative tests for official and nonofficial drugs, listed alphabetically; the next 29 pages are devoted to Oils, Fats and Waxes, the next 40 pages to Essential Oils and the next eight pages to Physical Methods.There are 13 appendices on Determination of Water, metallic impurities in organic substances, extraction of non-volatile organic materials from viscera, etc., determin- ation of alkaloids, elimination of emulsions, determination of alcohol content, titration in nonaqueous solvents, and tables of constants.The most closely related American books are Jenkins' Quantitative Pharmaceutical Chemistry, published in 1949 and Official Methods of Analysis of the Association of Official Agricultural Chemists, 1950.Since the first edition of Garratt's book appeared in 1937, there was a distinct need for the 1955 second edition.
"Coronary heart disease" is not tautologous
Authors: H. Tunstall-Pedoe
Journal: BMJ (2001)

Mercury sphygmomanometers: disposal has far reaching consequencesEditor-The papers by O'Brien and Beevers et al have documented the trend away from the use of the mercury sphygmomanometer. 1 2 But the ethical, legal, economic, and public health consequences associated with their disposal have not been so well documented.This lack of advice is surprising since mercury has well known toxic properties.Haphazard disposal of mercury inevitably leads to environmental recycling and bioconcentration, with ecological damage at best and human poisoning at worst. 3 The Special Waste Regulations 1996 classify mercury and waste material containing more than 3% mercury as special waste and require extensive documented control of, and the use of approved contractors for, each stage of the disposal process.Noncompliance can result in a major fine, together with a custodial sentence.Although technically only the mercury component is special, it would not be safe for staff to break sphygmomanometers open to access the mercury in uncontrolled conditions.In addition, we considered it likely that standard mercury containing sphygmomanometers used in general prac-tice in England and Wales would contain more than 3% mercury and should therefore be considered special waste.We obtained four intact mercury sphygmomanometers from a general practitioner's surgery and drained and weighed the mercury under laboratory conditions.Each contained more than 3% mercury (average 6.5%).The NHS must develop a policy for the storage and ultimate disposal of retired mercury sphygmomanometers that accords with the Special Waste Regulations 1996.Data from Birmingham health authority show that more than 30 000 mercury sphygmomanometers are still in active use by general practitioners in the UK.If plans are not made to dispose of these sphygmomanometers safely, some 1800 kg of mercury could enter the environment.The contamination that would result from the haphazard disposal of all mercury sphygmomanometers used in the NHS would be much greater, and the volumes involved suggest that collection and recycling may be commercially viable.What should general practitioners, hospitals, and other NHS trusts do?Expecting each to negotiate a suitable system of collection and disposal would be burdensome, inefficient, and impractical, although it is their legal responsibility to do so.We are working with the environment agency in our region to develop an approved scheme that will reduce the bureaucratic demands on individual practices while protecting them from statutory action and, at the same time, provide a safe, efficient, and cost effective storage, transport, and disposal service.
The impact of treatment for osteosarcoma on long term survivors with therapy of increasing dosage and dose intensity
Authors: I. J. Cohen, S. Ash, Y. Goshen, E. Boneda, M. Berant, I. Meller, J. Isaakov, I. Buchvall, Y. Kollender, I. Yaniv
Journal: Journal of Clinical Oncology (2004)

8571 Background: The increase in treatment dosage and intensity in the last 30 years of therapy for osteosarcoma could cause side effects that would tend to offset the improvement in prognosis. Methods: surviving patients treated at this center were interviewed, examined and their charts were reviewed. Results: The 5 year survival of non-metastatic limb osteosarcoma patients has increased from 30% (1973–1979) to 69%(1980- 1989) to 79% (1989–2003). (Int. J. Oncol 15:179–185,1999) These protocols include High Dose Methotrexate Adriamycin and Cisplatinum. This has not been associated with an increased morbidity and the long-term outcome has been remarkably good. 35 patients underwent surgery for limb tumors. Amputation was performed in 7 (all before 1989). 9 of 14 girls now over 18 years have married and have 23 normal children. Two of 10 boys now over 18 years have married (5 lost to follow up) and have 3 normal children. Detailed neuropsychological testing has been performed on 15 patients and no evidence of damage has been found that interferes with normal day to day activities.14 completed 12 years of schooling and 10 completed further education (university, talmudic collage or technical training). Cardiac function was examined in 34 patients, last examination normal (ejection fraction >50%, shortening fraction >28%) in 79% on the previous protocol containing 450mg/m2 of adriamycin. On the current protocol with 360mg/m2 it was normal in all patients except one. Conclusions: Patients and families can be reassured that the long-term side effects of therapy are not a major problem even with aggressive therapy. No significant financial relationships to disclose.
Synthetic vitamin A analogue (isotretinoin) awaiting approval for cystic acne therapy
Journal: JAMA (1982)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
LAW AND MEDICINE
Journal: JAMA (1968)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Measles Vaccination
Authors: Mark S. Dine
Journal: JAMA (1976)

<h3>To the Editor.—</h3> The most common immunization error I encounter on review of the records of new patients is the administration of measles vaccine under the age of 1 year—without a later booster dose of vaccine. The article of Rand et al (236:1028,1976) emphasizes the urgent need for the family physician, the internist, the school physician, and the pediatrician to review carefully the immunization records of all of their new patients. Children born between 1963 and 1967 are most likely to have received this immunization under 1 year—but I have encountered children born in 1974 who were immunized at 8 to 11 months of age. That in 50% of these children immunity does not develop was proved in my own practice in 1971.<sup>1</sup>The effectiveness and safety of a single booster was demonstrated in the report.
Abstract 1100: Genetic driver-mutations define composition and properties of tumor-associated myeloid cells in glioblastoma
Authors: Zhihong Chen, Cameron J. Hurting, Ben Gabanic, Jyothi Murukuti, Dolores Hambardzumyan
Journal: Cancer Research (2019)

Abstract The GBM microenvironment is composed of numerous non-neoplastic cells, among which tumor-associated myeloid cells (TAMs) are the most abundant. TAMs are constituted of several different cell types, including brain microglia and bone-marrow-derived infiltrating cells, which can be further divided into inflammatory monocytes, monocyte-derived macrophages, and polymorphnuclear neutrophils. These myeloid cells are believed to promote tumor growth and immune evasion by expressing immune checkpoint proteins. Remarkable progress has been made in treating lung cancer and melanoma by using immune-checkpoint inhibitors; however, mixed results were obtained for its application in GBM. To examine how molecular-subtypes of GBM influence the composition and immunosuppression of tumor-associated myeloid cells, we used the RCAS_tv-a system, a somatic cell-specific gene transfer system, to generate de novo murine GBM (mGBM). By manipulating different known human oncogenic-driver mutations such as overexpressing PDGFB or EGFRVIII, or silencing NF1, we generated Proneural (PN), Classical (CL) and Mesenchymal (MES) GBMs respectively, which phenotypically resemble their human counterparts. We found that the majority (80%) of tumor-infiltrating myeloid cells in PN GBM are bone-marrow derived macrophages, whereas this number is significantly less in CL and MES mGBM. Interestingly, unique to MES, there is a significant presence (16%) of neutrophils in these tumors than in other subtypes (4%). Further characterization for subtype-specific expression of PD-L1, a druggable immune checkpoint molecule, by flow cytometry shows that MES has the highest expression of PD-L1), whereas the expression is lower in PN and CL subtypes. Treating GBM-bearing mice with anti-PDL1 antibodies did not prolong their survival. Concurrent treatment of irradiation and anti-PDL1 antibody did not confer significant survival advantage either compared to controls. These results reflect the unsuccessful trails of recent human clinical studies; however, it also emphasizes the importance of understanding the mechanism of resistance in GBM immunotherapy before effective immune treatment can be established. Our immunocompetent mouse models provide indispensable tools for these studies. Note: This abstract was not presented at the meeting. Citation Format: Zhihong Chen, Cameron J. Hurting, Ben Gabanic, Jyothi Murukuti, Dolores Hambardzumyan. Genetic driver-mutations define composition and properties of tumor-associated myeloid cells in glioblastoma [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 1100.
Outbreak of Cryptosporidiosis at a Day Camp— Florida, July-August 1995
Journal: JAMA (1996)

On July 27, 1995, the Alachua County Public Health Unit (ACPHU) in central Florida was notified of an outbreak of gastroenteritis among children and counselors at a day camp on the grounds of a public elementary school. This report summarizes the outbreak investigation, which implicated Cryptosporidium parvum as the causative agent and underscores the role of contaminated water as a vehicle for transmission of this organism.
Current Comment
Journal: JAMA (1929)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal