tbuckley/cabot-search huggingface dataset:
THE ST. LOUIS SESSION
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Evaluation of Degree of Ammoniemia in Diagnosis of Digestive Hemorrhages
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Heparin-induced spinal fractures
Authors: J. W. Squires
Journal: JAMA (1979)

A 27-year-old woman received heparin sodium for 152 days because of antepartum iliofemoral thrombophlebitis. At the end of this time, spinal osteoporosis and multiple vertebral fractures became clinically evident and were attributed to the prolonged administration of heparin. Previously reported cases of "heparin osteoporosis" were reviewed. The significance of the daily dose of heparin and the duration of therapy are reemphasized. This therapeutic complication and the management of antepartum iliofemoral thrombophlebitis are discussed. Prolonged administration of heparin in daily doses exceeding 10,000 units is potentially hazardous. (<i>JAMA</i>241:2417-2418, 1979)
Common law and clinical investigation
Authors: Richard P. Bergen
Journal: JAMA (1968)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Identifying high-risk primary-prevention patients for lipid-lowering therapy: A comparison of the national cholesterol education program guidelines and framingham absolute risk assessment Terry A. Jacobson, Peter W. F. Wilson, Godfrey G. Griffiths, Cristina Varas, Douglas Gause, Jenny C. Y. Sung, Christie M. Ballantyne. Baylor College of Medicine, Houston, TX
Journal: Journal of the American College of Cardiology (2001)
Neurology
Authors: R. J. Joynt
Journal: JAMA (1991)

The role of neurologists in diagnosing and treating diseases of the nervous system also affords an opportunity to learn about the function of the nervous system. The advent of new imaging techniques has greatly expanded this opportunity. Precise localization of lesions by magnetic resonance imaging and delineation of disturbed function of certain brain areas by positron emission tomography have led to new ideas on brain-behavior linkages and to novel hypotheses about neural organization. One group of investigators using some of these techniques, along with extensive neuropsychological testing, has shown that specific types of memory may have quite diverse localization in the brain.<sup>1</sup>This alters the traditional view that memory is largely stored in one neural system. They also propose that neural processing takes place in convergence zones. Thus, there are a series of regions with information moving forward and backward so that final representation in the convergence zone is
Transactions of the Medical Society of the State of California During the Years 1883 and 1884.
Journal: JAMA (1884)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Differences in thyroid cancer.
Journal: BMJ (1972)

through poor social conditions and isolation either in a remote rural community or within a subculture in an in- dustrialized town experience overcrowding, loss of privacy, and a sense of estrangement from normal society which facilitates breakdown of normal standards.Such families commonly make heavy demands on medi- cal and social services, so that the doctor or his colleagues in the community may be the first to suspect incestuous behaviour.The law reacts in a way which reflects society's abhorence of paternal incest and the offender is usually committed to prison, where his fellow prisoners may inflict their own crude additional punishment for his offence.9On discharge, if the family has not broken up, the incestuous relationship is commonly resumed in conditions made worse by the father's conviction.Early identification of families at risk and prompt intervention may offer some prospect of prevention.Such families need sensitive, long-term social case work and major efforts to draw them into society.The high sexual drive of the fathers, whether due to lack of inhibition or biological excess, may be reduced by medication, and effective industrial rehabilitation might well be rewarded by a reduction in antisocial behaviour.Unless these family units can be helped to function more normally, they will continue to reproduce in each new generation the dis- ordered behaviour of the last.
Diagnostic evaluation of arrhythmic disorders. Clinical application of His bundle electrography
Authors: K. M. Rosen
Journal: JAMA (1974)

THE specialized cardiac conduction system consists of sinus node, atrioventricular node, His bundle, and the bundle-branch system. Impulse formation is normally initiated in the sinus node, while the other structures are necessary for conduction of the impulse from atrium to ventricles and for distribution of the impulse in an orderly fashion to the ventricles. Activation of the specialized conduction system is not seen directly on the surface electrocardiogram, which only shows activity of atrial muscle (P wave) and ventricular muscle (QRS complex). Abnormalities of the specialized conduction system are inferred from the surface cardiogram; eg, atrioventricular block, which produces abnormal conduction patterns between P waves and QRS complexes, and bundle-branch blocks, which produces a disordered QRS. Techniques are now available that allow a more direct look at the function of the specialized conduction system.<sup>1-4</sup>The most important of these is the catheter recording of His bundle electrograms. With catheterization of
Adherence to standard therapy for the treatment of childhood CNS tumors in Argentina. An audit perspective
Authors: E. G. Rivarola, G. L. Chantada, L. Ezcurdia, A. Negro, E. Gil Deza, D. Cascallar, D. Santillán, S. Carnaval, E. Morgenfeld, F. G. Gercovich
Journal: Journal of Clinical Oncology (2004)

8573 Background: There are no national protocols for the treatment of children with CNS tumors in Argentina, so patients receive individualized treatment at each center. The aim of this study was to evaluate, from an audit perspective, the treatment prescribed to children with CNS tumors belonging to a large health insurance organization in Argentina. Methods: The files of all patients with CNS tumors for whom their oncologists requested chemotherapy from 2000 to 2003 were retrieved. All patients were treated at prestigious institutions. The PDQ Cancer Information Treatment Summaries posted at the National Cancer Institute of USA web site was used to define standard therapy. Results: Requests of chemotherapy for 24 children treated at 8 different referral centers were received. There were 10 cases of medulloblastoma, 7 gliomas, 5 ependymomas, 1 malignant rhabdoid-teratoid tumor and 1 anaplastic tumor not otherwise specified. This case was excluded because no standard therapy is available. Overall, 9/10 children younger than 3 years of age received standard Baby's combination. Seventeen out of 23 patients received standard combinations as first line treatment while in 6/23 patients experimental treatment was prescribed. These included 1 children with brainstem glioma, 3 children with ependymoma and 1 one year old child with glioma that received an experimental combination. Even though the role of temozolomide is not clear in children, this drug was requested for 3 patients with glioma (1 baby) as first line and 2 for second line therapy (ependymoma and glioma). Topotecan was requested for 2 patients with ependymoma. All patients with medulloblastoma received standard therapy. Conclusions: Despite all patients were treated at prestigious centers, 46% of children with CNS tumors other than medulloblastoma received unproven first line therapy. "Off guidelines" treatments with unproven agents outside a clinical trial such as temozolomide and topotecan were requested for 30% of the cases. According to ethical principles, it is our feeling that all children with malignancies outside a controlled clinical trial should receive standard therapies. No significant financial relationships to disclose.
Induction of Histamine Release in Vitro from Rat Peritoneal Mast Cells by Extracts of Grain Dust
Authors: C. P. W. Warren, V. Holford-Strevens
Journal: Environmental Health Perspectives (1986)

The ability of extracts of grain dust and wheat to induce histamine release from rat peritoneal cells was investigated. Some grain dusts, with a high endotoxin content, were found to produce cytotoxic histamine release. Extract of wheat dust, with a low endotoxin release, produced noncytotoxic histamine release from peritoneal cells but not from purified mast cells. This reaction was dependent on the presence of phosphatidyl serine. The agent did not appear to be a lectin because histamine release was not enhanced by passive sensitization of mast cells with IgE. The activity occurred only over a narrow range of concentrations of the extract of wheat. The cause was unclear.
Comparison of adjuvant chemoradiation to peri-operative chemotherapy for the treatment of resected gastric and gastroesophageal junction adenocarincoma.
Authors: Haerin Kim, Christian K. Kollmannsberger, Devin Schellenberg, Winson Y. Cheung, Howard John Lim
Journal: Journal of Clinical Oncology (2012)

103 Background: Currently there are several accepted peri-operative treatment modalities for the resected gastric (GC) and gastroesophageal junction (GEJ) adenocarcinoma. In the 2008, peri-operative chemotherapy (CRT) using the MAGIC was adopted as the preferred approach to adjuvant chemoradiation with the MacDonald protocol (cXRT) in the British Columbia. An era to era comparison was performed to determine if there were differences in outcomes. Methods: Data from the pharmacy records of patients (pts) referred to 1 of 5 cancer treatment in BC were analyzed from 2001- July 2010. Pts that underwent curative resection for GC or GEJ were only included. cXRT cohort was defined from Jan 2001-Dec 2007, prior to the CRT era. CRT cohort started from Jan 2008-July 2010. Descriptive statistics were used to compare the groups. Survival analysis was performed using Kaplan Meier methods. Results: The Table summarizes the patient characteristics. In the CRT arm, there were more males, less pts with a LN ratio &gt;0.2 and shorter median follow-up. 92.1% completed the pre-op chemotherapy and 44.7% completed post-op chemotherapy whereas 73.3% of pts completed cXRT (p&lt;0.05). 1 yr survival was similar between the 2 cohorts. Median overall survival was not reached in the CRT arm and was 64.1 months in the cXRT arm. Conclusions: Delivery of CRT was similar to that in the MAGIC trial. Outcomes of CRT compared to cXRT appears to be similar in this cohort to cohort study with similar 1 yr survival. Pre-operative CRT results in less pts with a LN ratio &gt; 0.2. Further follow-up is needed with respect to relapse and overall survival. Either modality can be considered for peri-operative management of GC or GEJ adenocarcinoma. [Table: see text]
Abstract 234: Expression of Activated PKCϵ Accelerates the Transition to Heart Failure in Response to Increased Hemodynamic Load
Authors: Milana Yuzhakova, David L Geenen, Paul H Goldspink
Journal: Circulation (2008)

Expression of constitutively active PKCϵ in the myocardium promotes a steady progression to a dilated cardiomyopathy over time. Functional and biochemical studies demonstrate that the myofibrillar proteins are a target of PKCϵ mediated phosphorylation. In this model, changes in myofibrillar protein phosphorylation at 3-months are associated with compensatory mechanisms, whereas at 9 and 12-months are associated with the transition to failure. To test the hypothesis that PKCϵ phosphorylation alters the post-translational modification of the contractile proteins and that these changes predispose the heart to failure, we imposed a hemodynamic load on young mice (3-mice). Both transgenic (TG) and non-transgenic (NTG) mice were banded (AoB) for 10 weeks before assessment of cardiac function in vivo , gene expression and 2-D electrophoresis of myofibrillar extracts. Analysis of heart weight to body weight ratios (3mNTG=4.3±0.4 vs. 3mTG=4.2±0.3 vs. 3mNTG(AoB)= 5.9±0.3* vs. 3mT-G(AoB)=7.4±0.6** *p&lt;0.05), shows hypertrophy in both groups of AoB mice, but to a greater degree in the TG (AoB). Gene expression analysis using quantitative qRT-PCR shows significant increases in both ANF and β-MHC mRNA in AoB mice compared with non-banded groups. Expression was significantly greater in the TG (AoB) along with a decrease in SERCA mRNA. Banding induced both diastolic and systolic dysfunction in TG compared to NTG hearts. Maximal −dP/dt in the TG (AoB) hearts was significantly lower compared to all other groups (3mNTG=9433±1000 vs. 3mTG=9474±857 vs. 3mNTG(AoB)=8620±1264 vs. 3mT-G(AoB)=4911±738* mmHg/sec, *p&lt;0.05). Load-independent measurements revealed a significant decreases the time constant of isovolumic relaxation (3mNTG(AoB)=5.4±0.6 vs. 3mTG(AoB)=8.4±1.5* ms). In addition, maximal +dP/dt-end diastolic volume relation (3mNTG(AoB)=213±64 vs. 3mTG(AoB)=79±20*, p&lt;0.05) was significantly depressed in banded TG compared to banded NTG. 2-D gel analysis of myofibrillar proteins revealed hyper-phosphorylation of troponin I in the PKCϵ TG mice. These data suggest that while the TG hearts have compensated to an initial insult (PKC activation) imposition of a second insult (hemodynamic load) accelerates the transition to failure.
Minerva Chirurgica, Turin
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
CONTRACT PRACTICE.
Journal: JAMA (1906)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
PRACTICAL NOTES
Journal: JAMA (1891)

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THE PATHOGENESIS OF ACROMEGALIA.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal