tbuckley/cabot-search huggingface dataset:
Contents
Authors: R Moreau, R Bataller, T Berg, J Zucmann-Rossi, R Jalan, -F Yip, -Y Chan, -S Wong, Y.-K Tse, -Y Lam, -H Wong, H Samji, A Yu, M Kuo, M Alavi, R Woods, M Alvarez, G Dore, M Tyndall, M Krajden, N Janjua, Bc Testers, K.-G Simon, S Mauss, E Schott, R Heyne, D Klass, C Eisenbach, T Welzel, R Zachoval, G Felten, J Schulze, T Gallo, J Warger, Finite Petersen, H Dalton, J Van Eijk, P Cintas, R Madden, C Jones, G Webb, B Norton, J Pique, S Lutgens, N Devooght-Johnson, K Woolson, J Baker, M Saunders, L Househam, J Griffiths, F Abravanel, J Izopet, N Kamar, N Van Alfen, B Van Engelen, J Hunter, A Van Der Eijk, R Bendall, B Mclean, B Jacobs, H Nagata, M Nakagawa, Y Asahina, A Sato, Y Asano, T Tsunoda, M Miyoshi, S Kaneko, S Otani, F Kawai-Kitahata, M Murakawa, S Nitta, Y Itsui, S Azuma, S Kakinuma, T Nouchi, H Sakai, M Tomita, M Watanabe, C Bureau, D Adebayo, M Chalret De Rieu, L Elkrief, D Valla, M Peck-Radosavljevic, A Mccune, V Vargas, M Simon-Talero, J Cordoba, P Angeli, S Rosi, S Macdonald, M Malago, M Stepanova, Z Younossi, C Trepte, R Watson, O Borisenko, S Sun, R Carnevale, V Raparelli, C Nocella, S Bartimoccia, M Novo, A Severino, E De Falco, V Cammisotto, C Pasquale, C Crescioli, A Scavalli, O Riggio, S Basili, F Violi, P Trivedi, I Scalera, E Slaney, R Laing, B Gunson, G Hirschfield, A Schlegel, J Ferguson, P Muiesan, S Roy, H Bantel, F Wandrer, A Schneider, J Gautheron, M Vucur, F Tacke, C Trautwein, T Luedde, C Roderburg
Journal: Journal of Hepatology (2017)
Abstract 2474: Dynamic Change in LV Twist Mechanics in a Canine Model of Pacing-Induced Heart Failure
Authors: Jianwen Wang, Sherif F Nagueh, Nilesh Mathuria, April L Gilbert, Daryl G Schulz, Dorin Panescu, Hue-Teh Shih, Dirar S Khoury
Journal: Circulation (2007)

Background : LV twist may reflect LV contractility under different conditions. This study investigated LV twist dynamics and its determinants in a canine model of congestive heart failure (CHF). Methods : Pacemakers and percutaneous leads were implanted in 8 adult hound dogs (mean weight, 38 kg), and continuous chronic RV pacing was applied at 230–250 bpm until CHF induction. Subsequently, pacing was turned off to allow the heart to recover. Echocardiography and LV catheterization were performed simultaneously at baseline, during CHF while pacing was temporarily switched off, and during recovery from CHF after pacing was stopped. CHF induction by pacing was repeated in 4 dogs. Apical and basal rotations were measured using 2D speckle tracking, and LV twist was calculated as the difference between apical and basal rotations. Untwisting rate was calculated as the peak diastolic time derivative of LV twist. Results : CHF developed after 2–4 wks of pacing with LV end-diastolic volume (LVEDV), end-systolic volume (LVESV), end-diastolic pressure (LVEDP), and time constant of LV relaxation during isovolumic relaxation period (tau) all increasing significantly compared to baseline (Table ), and recovering to baseline levels 2–4 wks after pacing was stopped. LV twist and untwisting rate decreased with CHF compared to baseline, and improved during recovery from CHF although the change in untwisting rate between CHF and baseline was not significant. In pooled data, LV twist was significantly related to LVEDV (r=-0.60, P&lt;0.001), LVESV (r=-0.59, P=0.001), LVEF (r=0.81, P&lt;0.001), LVEDP (r=0.41, P=0.03) and +dp/dt (r=0.71, P&lt;0.001), but not with end-systolic pressure (r=0.06, P=0.77). In multiple analysis, +dp/dt was the only independent predictor of twist (P &lt; 0.001). Conclusions : LV twist dynamics can reflect the presence of pacing-induced CHF and its recovery. LV contractility appears to be the only determinant of LV twist in CHF.
Studies of Mental Defects and Handicaps.
Journal: JAMA (1925)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Diets for Infants and Children in Health and in Disease.
Journal: JAMA (1896)

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INFECTION FROM BOOKS.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
GENERAL PRACTITIONER AWARD
Journal: JAMA (1952)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
American Cancer Society National Conference on the Care of the Child With Cancer
Journal: JNCI Journal of the National Cancer Institute (1978)

Journal Article American Cancer Society National Conference on the Care of the Child With Cancer Get access JNCI: Journal of the National Cancer Institute, Volume 60, Issue 5, May 1978, Page 1183, https://doi.org/10.1093/jnci/60.5.1183-a Published: 01 May 1978
Tacrine and lecithin in Alzheimer's disease.
Journal: BMJ (1990)

SIR,-As two general practitioners in Bradford who are actively concerned in providing maternity care we would like to comment on the paper by Dr F C Bryce and colleagues on general practitioner obstetrics in Bradford.'We have worked in Bradford in different practices for two years and one year respectively.We both have experience of schemes of community antenatal care in Hackney and Tower Hamlets that are looselv based on the Sighthill model.2We are convinced that such schemes succeed because of cooperation between hospital and community staff, which results from the development and implementation of agreed protocols for maternity care.In contrast we found that the lack of any such protocols in Bradford and the poor communication among colleagues created a sense of isolation among general practitioner obstetricians.We were first aware of the paper by Dr Brvce and colleagues in September 1989, when an earlier draft was circulated to local general practitioners.There was no general practitioner or midwife participation in the preparation of the paper.Its tone was felt by many general practitioners to be admonitory and divisive.Trhere was an immediate response bv general practitioners in Bradford, manv of whom wrote letters to the local medical committee, which prepared a paper in response.No further communication occurred until the obstetricians' paper, slightly modified, appeared in the BM7, almost six months after we had first seen it.As far as we are aware no account had been taken of the large response from general practitioners that it had generated.The thrust of our response to the original paper was that the key to better maternity care in Bradford is good communication and cooperation among all those concerned: consumers, midwives, general practitioners, and consultants.We regret the style of the paper and would question its scientific validity in view of the small numbers studied.Nevertheless, we welcome the opening up of the debate and hope that it may be possible to move the discussion out of the hospital and into the community.Specifically, we propose that consul- tants should come into the community clinics on a regular basis.This would lead to improved communication.Consultants would share their expertise and provide continuing clinical advice and education.Midwives and general practitioners would benefit from the support provided by such contact, and, above all, the women of Bradford would benefit from expert, well planned, locally based maternity care.
Old Age and Hemochromatosis
Journal: JAMA (1992)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Retinoblastoma Surprise
Authors: Tracy Hampton
Journal: JAMA (2007)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Weber-Christian disease. Report of a case documenting the presence of leukoagglutinins
Authors: H. A. Rosenstock
Journal: JAMA (1968)

Weber-Christian disease is the eponymous designation of an idiopathic, relapsing, febrile, nodular, and nonsuppurative panniculitis. The presence of leukoagglutinins in the absence of a transfusion history and the peculiar response to intradermal injection of an autologous buffy coat tend to support the contention that this disease may constitute merely a histiologically specific, hyperergic response.
A Manual of Midwifery.
Journal: JAMA (1907)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Inhibition of β-catenin–TCF1 interaction delays differentiation of mouse embryonic stem cells
Authors: Sujash S. Chatterjee, Abil Saj, Tenzin Gocha, Matthew Murphy, Foster C. Gonsalves, Xiaoqian Zhang, Penelope Hayward, Betül Akgöl Oksuz, Steven S. Shen, Aviv Madar, Alfonso Martinez Arias, Ramanuj DasGupta
Journal: The Journal of Experimental Medicine (2015)
Council on Pharmacy and Chemistry
Journal: JAMA (1941)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Direct Technique Measures Aqueous Humor Formation Rate
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Development of Quantitative Structure-Pharmacokinetic Relationships
Authors: Joachim M. Mayer, Han van de Waterbeemd
Journal: Environmental Health Perspectives (1985)

Quantitative structure-activity relationships (QSAR) relating biological activity to physiochemical descriptors have been successfully used for a number of years. It is also long recognized that pharmacokinetic parameters may play an important and even determinant role in drug action. This prompted several researchers to focus attention to pharmacokinetic parameters as potential descriptors in quantitative drug design. A number of examples of quantitative structure-pharmacokinetic relationships (QSPR) have appeared in the literature. The present contribution reviews some developments in this field. In particular, a number of concepts and problems are critically discussed, rather than compilations of examples already published in recent reviews. Attention will be paid to the main processes of the pharmacokinetic or toxicokinetic phase in drug action, including absorption, distribution and elimination (biotransformation and excretion). It is clear that quantitative approaches are of considerable interest to toxicologists, since these methods may contribute to the development of real predictive toxicology.
Nuclear scaffold-associated protease:In situ nuclear localization and effects of a protease inhibitor on growth and morphology of aras-transformed hepatocyte cell line
Authors: Gary A. Clawson, Ling Ren, Harriet C. Isom
Journal: Hepatology (1995)

We have previously identified a multicatalytic protease (MCP) activity associated with the nuclear scaffold (NS) in hepatocytes and fibroblasts. When we used the chloromethylketone protease inhibitor AAPF cmk , which is targeted to chymotrypsinlike protease activity, we observed a dramatic inhibition of transformation of fibroblasts, with effects that were relatively selective for the NS fraction. Here, we undertook experiments to determine the effects of AAPF cmk on Simian Virus 40-immortalized CWSV1 cells compared with a ros -transformed hepatocyte cell line (NR4) derived from CWSV1. We used biotin AAPF cmk and fluorescent reagents to demonstrate a nuclear chymotrypsinlike protease activity, which is most prominent at the nuclear envelope. The ras -transformed NR4 cells were highly susceptible to growth inhibition in a dose-dependent manner, showing 85% growth inhibition at 50 μmol/L AAPF cmk . In contrast, the immortalized CWSV1 cells were not sensitive at the concentrations (10 to 50 μmol/L) of AAPF cmk tested. In subcellular fractionation studies, the inhibitory effects of AAPF cmk were confined to the NS fraction. The AAPF cmk -induced growth inhibition was accompanied by marked morphological changes in ras -transformed cells, without evidence of overt toxicity. No change in DNA content was observed, but a marked increase in organization of actin cytoskeletal elements was seen. These results suggest that a protease activity associated with the nuclear scaffold has important functions in controlling cytoskeletal filament organization and cell replication. (Hepatology 1995; 22:1230-1235.).
Low dose docetaxel, estramustine and thalidomide followed by maintenance thalidomide for the treatment of hormone refractory prostate cancer (HRPC): A phase II community based trial
Authors: R. C. Frank, A. Coscia, L. Versea, N. Cohen, R. Zelkowitz, A. Ruskin, A. Skeris, P. Dodds, K. Nair
Journal: Journal of Clinical Oncology (2004)

4681
Incomplete Affiliations Given for 2 Authors
Journal: JAMA Oncology (2020)

Javier Martin-Broto, MD, PhD; Nadia Hindi, MD; Antonio Lopez-Pousa, MD; Javier Peinado-Serrano, MD; Rosa Alvarez, MD; Ana Alvarez-Gonzalez, MD; Antoine Italiano, MD; Paul Sargos, MD; Josefina Cruz-Jurado, MD; Josep Isern-Verdum, MD; Maria Carmen Dolado, MD; Inmaculada Rincon-Pérez, MD; Paloma Sanchez-Bustos, MSc; Antonio Gutierrez, MD, PhD; Cleofe Romagosa, MD, PhD; Carlo Morosi, MD; Giovanni Grignani, MD; Marco Gatti, MD; Pablo Luna, MD; Ignacio Alastuey, MD; Andres Redondo, MD, PhD; Belen Belinchon, MD; Jordi Martinez-Serra, PhD; Marie-Pierre Sunyach, MD; Jean-Michel Coindre, MD, PhD; Angelo P. Dei Tos, MD, PhD; Jesus Romero, MD, PhD; Alessandro Gronchi, MD; Jean-Yves Blay, MD, PhD; David S. Moura, PhD