tbuckley/cabot-search huggingface dataset:
members of the house of delegates
Journal: JAMA (1971)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
PTU-134 What do young people and parents want from an inflammatory bowel disease (IBD) service?
Authors: R Little, C Imrie, A Derby, P Gillespie, G R Caddy, T C Tham
Journal: Gut (2012)

<h3>Introduction</h3> At present, there are guidelines from the US and Europe regarding the formation of transition clinics for adolescents with IBD. This includes a UK Inflammatory Bowel Disease (IBD) Standards guidance on optimal service provision for paediatric and adolescent care. However most of these guidelines come from intuitive reasoning and opinion, as there is a lack of data on what constitutes an ideal service for young patients with IBD. The aim of this study was to develop a comprehensive knowledge and understanding of the key service requirements of young people with IBD as well as their parents. <h3>Methods</h3> Paediatric and adolescent patients age 6–18 years, were identified from databases in two teaching hospitals and from the membership of the N Ireland branch of Crohn9s and Colitis UK, which is a patient support group. Anonymous questionnaires were sent to these patients and their parents separately. The questionnaires asked about their perceived quality of care, clinic care, general comments, input from specialists, support and information, plus any suggestions. <h3>Results</h3> 105 questionnaires were sent and 51 responded (49%); of these 21 were from patients and 30 from their parents. Over 84% were happy with the quality of care they are receiving. Reasons patients and parents were reluctant to attend clinics included: blood tests, nurse specialist or doctor not available, lack of car parking. 90% preferred to see the attending (Consultant) rather than a fellow. Nurse specialist, dietetics, specialist IBD surgeon, psychologist, skin/eye specialist input was thought to be beneficial by 95%, 81%, 71%, 59%, and 45% respectively. The following support service and information were considered important: immediate contact with healthcare personnel for disease flare, support groups for young adults, insurance and financial advice, knowledge about IBD developments and research, email service, surgical input regarding stomas. <h3>Conclusion</h3> The majority of young patients with IBD and their parents are satisfied with the care they are receiving. Support from specialist services such as nurse specialist, dietitians, specialist IBD surgeons, psychologist, plus rapid access to services when the disease flares were thought to be important by the patients and their parents. Knowledge of what these patients and their parents want will help to design an optimal IBD service. <h3>Competing interests</h3> R Little: None Declared, C Imrie Conflict with: Mead Johnson, Falk Pharma, Nutricia, Warner Chilcott, SHS, Norgine, Wyeth, A Derby: None declared, P Gillespie: None declared, G Caddy: None declared, T Tham Speaker bureau with: Warner Chilcott, Shire, Conflict with: Abbott, MSD.
GI highlights from the literature
Authors: Mairi H McLean
Journal: Gut (2015)

<h3>Objective</h3> To determine the prospective association between physical workload—in terms of specific physical exposures and the number of exposures—and long-term sickness absence (LTSA). <h3>Methods</h3> Using cox-regression analyses, we estimated the risk of register-based incident LTSA (at least 3 consecutive weeks) from self-reported exposure to different physical workloads among 11 908 wage earners from the general working population (Danish Work Environment Cohort Study year 2000 and 2005). <h3>Results</h3> The incidence of LTSA was 8.9% during two-year follow-up. Spending 25% or more of the total work time with a bent or twisted back (HR 1.59 (95% CI 1.39 to 1.83)), arms above shoulder height (HR 1.35 (95% CI 1.14 to 1.59)), squatting or kneeling (HR 1.30 (95% CI 1.09 to 1.54)), pushing/pulling or lifting/carrying (HR 1.40 (95% CI 1.22 to 1.62)) and standing in the same place for 50% or more of total work time (HR 1.19 (95% CI 1.00 to 1.42), were risk factors for LTSA when adjusted for baseline age, gender, psychosocial work environment, lifestyle, musculoskeletal and mental disorders, and socioeconomic status. HR increased from 1.25 (95% CI 1.04 to 1.51) for one to 1.94 (95% CI 1.56 to 2.41) for four combined physical workloads. Results largely remained stable in subgroup analyses including only blue-collar workers (n=5055). Population attributable risks for LTSA from one or more physical workloads were 26% and 40% in the general working population and among blue-collar workers, respectively. <h3>Conclusions</h3> Several of the investigated types of physical workload were risk factors for LTSA when exceeding 25% of the work time. A higher number of combined physical workloads was associated with progressively increased risk. Our study underscores the importance of physical workload as risk factors for LTSA in the general working population as well as among blue-collar workers.
Basis for Occupational Health Standard
Journal: JAMA (1992)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Massive haemoptysis.
Journal: BMJ (1969)

BRfiTsH 669 babies died, one had normal levels of H.P.L., one had higher than normal levels, and one had low levels.These authors were therefore unimpressed with the general value of such determinations.The chief contender among diagnostic tests for placental insufficiency is the determination of urinary oestriol levels.This is now well established, and in contrast to H.P.L. it measures the function of the foetus and placenta together as a unit.However, if measurement of H.P.L. proves to be of similar value, then it offers the advantages that it can be performed on single blood samples and that larger numbers of tests can be carried out.But the evidence on its value is conflicting and further work on it is needed.
Fluoroscopy technique for tumor localization
Authors: E. E. Covington
Journal: JAMA (1966)

FOR several years I have been dissatisfied with x-ray films alone for localization of a tumor. Films will show the bony wall of the chest or pelvis, but a soft-tissue mass or tumor may not be well defined on the film. Thus, accurate localization and depthdose measurements are not possible. Fluoroscopy is the easiest, fastest, and most accurate method of localization. If possible, an opaque substance should first be introduced, and then located by fluoroscopy. The opaque substance will vary from a dummy radium capsule in the cervix to a contrast medium in the bladder or barium in the esophagus. Lead markers are placed on the skin during the fluoroscopy. They indicate the center point for the x-ray or cobalt-60 therapy portals. X-ray films, anteroposterior (AP) and lateral, are taken in the exact position (prone, supine, or oblique) in which the patient is to be treated, for confirmatory evidence of
Book Reviews
Authors: Giovanni A. Fava, Hellmuth Freyberger, Harald-J. Freyberger, Julian Iancu, Moshe Kotler, Baruch Spivak, Margaret Radwan, Avraham Weizman, K. Lovell, I.M. Marks, H. Noshirvani, G. O'Sullivan, Mark A. Lumley, Karen Downey, Laurence Stettner, Francine Wehmer, Ovide F. Pomerleau, Per Høglend, Oscar Heyerdahl, Thomas Middelboe, Lars Ovesen, Erik Lykke Mortensen, Per Bech, M. Ercolani, G. Trombini, R. Chattat, C. Cervini, G. Piergiacomi, F. Salaffi, S. Zeni, R. Marcolongo, Lluisa Garcia, Manuel Valdés, Inmaculada Jódar, Nadine Riesco, Tomás de Flores, Giulia Perini, Michele Zara, Roberto Cipriani, Christian Carraro, Antonio Preti, Franco Gava, Paola Coghi, Andrea Peserico, O. Todarello, A. Casamassima, M. Marinaccio, M.W. La Pesa, L. Caradonna, L. Valentino, L. Marinaccio, Vanja Blomkvist, Töres Theorell, Hans Jonsson, Sam Schulman, Erik Berntorp, Lennart Stiegendal, Joel A. Pava, Maurizio Fava, Janet A. Levenson
Journal: Psychotherapy and Psychosomatics (1994)
THE NATURE OF THE CELLS IN PIGMENTED MOLES.
Journal: JAMA (1902)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
ON THE SEROLOGICAL SPECIFICITY OF PEPTIDES. II
Authors: K. Landsteiner, J. van der Scheer
Journal: The Journal of Experimental Medicine (1934)

In continuation of previous studies immune sera for azoproteins made from aminobenzoyl dipeptides and tripeptides were tested with various peptide azoproteins by precipitin tests and with nitrobenzoyl derivatives of peptides by means of inhibition reactions. When examined with the latter method, the immune sera exhibited a high degree of specificity and permitted the recognition of distinctions among peptides of similar structure.
Pronouncing
Authors: Brendan M. Reilly
Journal: Annals of Internal Medicine (2001)

On Being a Doctor18 September 2001PronouncingBrendan M. Reilly, MDBrendan M. Reilly, MDDr. Reilly: Cook County Hospital and Rush Medical College Chicago, IL 60612Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-135-6-200109180-00017 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Many years ago, when I was just starting out, I worked in a small New England town where local law stated that the newly deceased were not duly deceased until pronounced by a licensed physician. Legally, the undertaker couldn't take over—you weren't really dead—until a doctor said so.At first, this sounded harmless enough, even quaintly appealing, a vestige of simpler times when doctors really were gatekeepers, ushering lifeless folks out of the world and delivering new ones into it. But that whimsy dissipated soon. My nights on call, preoccupied plenty with the living, brought frequent “requests” to pronounce the ... Author, Article, and Disclosure InformationAuthors: Brendan M. Reilly, MDAffiliations: Dr. Reilly: Cook County Hospital and Rush Medical College Chicago, IL 60612Corresponding Author: Brendan M. Reilly, MD, Room 2129, Department of Medicine, Cook County Hospital and Rush Medical College, 1835 West Harrison Street, Chicago, IL 60612. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 18 September 2001Volume 135, Issue 6Page: 467-470KeywordsBeerFallsHeartHeart rateHospital medicineMouthNursesSkullSweatThorax ePublished: 18 September 2001 Issue Published: 18 September 2001 Copyright & PermissionsCopyright © 2001 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Abstract LB-135: Targeting the myeloid-cell specific SRC-kinase HCK improves anti-tumor immunity
Authors: Matthias R. Ernst, Ashwini Chand, Nicholas Huntington, Robert O'Donoghue, Ashleigh Poh
Journal: Cancer Research (2019)

Abstract Elevated expression of the myeloid cell-specific Src-family kinase HCK occurs in a majority of solid malignancies and correlates with poor patient survival [Poh et al., Frontiers Oncol 2018]. We have recently shown that genetic ablation, or therapeutic inhibition, of HCK suppresses the growth of primary tumors arising in the colon, stomach, lung and other mutagenized epithelia of mice. Mechanistically, we have attributed this to the capacity of HCK activity to support and retain the polarization of a wound-healing, Tie2+ (i.e. alternative activated) endotype of tumor-associated macrophages and concomitant tumor vascularization [Poh et al., Cancer Cell2017]. Here we extend these observations to MC38 colon cancer, B6/F10 melanoma and EO771 breast cancer allograft model, where the growth of the primary lesion and its metastatic spread is suppressed in HCK knockout hosts. More importantly, HCK gene deletion or therapeutic HCK inhibition with a small kinase inhibitor in mouse models further enhances the anti-tumor effects conferred by either chemotherapy or single agent immunotherapies based on anti-PD-L1, anti-CTLA4 or agonistic-CD40 antibodies. These observations are underpinned by increased tumour cell apoptosis that coincides with enhanced expression of ifng, gzmb, prf1 and other effector proteins in NK and infiltrating CD8+ cells. Likewise, HCK inhibition confers increased expression of il12 and ifng in tumor-associated macrophages, which adopt a more conventional activated endotype. Because HCK-deficiency of the host also associated with increased abundance of tumor infiltrating effectors cells, we propose that therapeutic targeting of HCK not only “makes tumors hotter”, but also improves host anti-tumor immunity. We are therefore developing novel HCK-specific small molecule inhibitors. Citation Format: Matthias R. Ernst, Ashwini Chand, Nicholas Huntington, Robert O'Donoghue, Ashleigh Poh. Targeting the myeloid-cell specific SRC-kinase HCK improves anti-tumor immunity [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr LB-135.
"THE INTERNE"
Authors: William Ruberman
Journal: JAMA (1949)

<h3>To the Editor:—</h3> In the May 14 issue ofThe Journalthere appeared a copy of a letter sent to the Association of Internes and Medical Students protesting the stand taken by its Convention on Health Insurance. It was prefaced by an editorial which can hardly be matched for its calumny and gross misstatement of facts. The letter, the editorial stated, protested a recent statement, "made in<i>The Interne</i>, a magazine said to be the publication of the interns' organization." It continued, "Apparently this organization includes relatively few interns and residents but claims to represent them all." <i>The Interne</i>, as can easily be ascertained by glancing at its cover, is the journal of the Association of Internes and Medical Students. The A.I.M.S. has never, and very obviously can never, claim to represent any but its own membership. It is possible that what has been confused is the fact that A.I.M.S.
Artificial heart implants began five years ago
Authors: V. S. Cowart
Journal: JAMA (1987)

THIS WEEK marks not only the 20th year of heart transplants, but the fifth anniversary of the first artificial heart implant. William DeVries, MD, who implanted the first artificial heart in Barney Clark, DDS, Dec 1 to 2 (overnight), 1982, says he is still looking for a suitable patient to continue the artificial heart program at Humana Hospital, Louisville, adding that such a patient would not be a candidate for transplantation. This would probably mean someone over age 60 years whose heart is in poor condition but who is relatively healthy otherwise. "Humana is very strong in its commitment to us," DeVries says. He adds that he also has Food and Drug Administration approval to continue. DeVries likens the state of the art in artificial heart technology to the heart transplantation program before cyclosporine. "It's still developmental and experimental," he says, "but there is a place for another mode of
Immunoaugmentative therapy: assessing an untested therapy
Authors: S. L. Nightingale
Journal: JAMA (1988)

The article on immunoaugmentative therapy (IAT) in this issue of<i>JAMA</i><sup>1</sup>is an important and timely one. Immunoaugmentative therapy has been widely promoted for well over a decade, and despite the lack of any genuine scientific study
The Lumleian Lectures on Aero-Therapeutics in Lung Disease: Delivered before the Royal College of Physicians of London
Authors: C. T. Williams
Journal: BMJ (1893)

OF CLIMATE.l,efore dealing with the subject of tllese lectures-airo- therapeutics, or the healing influences of climate on mankind -it will be necessary to say a few words on climate generally and briefly to consider its principal factors.The chief factors of any climate are:It will be seen from Diagram 2, issued from the Meteorologi- cal Office, which is the result of numerous observations of the Channel water made at the various lightships and coastguard This is well shown in Pike's Peak, where the mean daily range is about This half tnat noted on the prairie plain at its foot.
Do general practitioner deliveries constitute a perinatal mortality rate?
Journal: BMJ (1982)

Stress and illness SIR,-I would like to comment on Minerva's point (6 February, p 426) that whenever careful epidemiological research is done into the effects of stress on illness the answers tend to be negative.Even careful research cannot always come up with the right answer.Lifeevent scales are a very unsatisfactory way of evaluating the effects of stress for they omit exploration of one of the most potentially stressful areas of life-that is, family relationships.The only dimension of such relationships that life-event scales explore is frequency of arguments.Arguments, however, are not neccssarily the most stressful aspects of family life.Indeed, there is considerable evidence now that avoidance of argument and detouring of conflict is far more stressful.1Indeed, conflict avoidance is one of the main features in families containing "psychosomatic" illness.Other associated family characteristics are over- involvement, overprotectiveness, and rigidity.None of these are explored in the life-event scales.Further, it should be noted that once such family problems are treated there is often dramatic improvement in the illness.2
Pediatrics
Journal: JAMA (2001)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Rubella and Congenital Rubella— United States, 1984-1986
Journal: JAMA (1987)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal