tbuckley/cabot-search huggingface dataset:
Venous Perforation Due to Polyethylene Catheter
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The computer in medicine. Its application to medical practice, quality control, and cost containment
Authors: V. E. Pollak
Journal: JAMA (1985)

THE COMPUTER now plays a key role in many functions in society. It is an important instrument in modern medicine, but its application to day-to-day medical practice has had limited success. The modern physician acts in varying degrees as clinician, clinical investigator, and teacher, and often has clinical administrative responsibilities as well. These clinical, teaching, and administrative functions have been served most inadequately by the current medical record. Application of modern data-processing techniques to the practice of medicine and to the medical record may help in resolving this dilemma.<sup>1</sup> The nephrologist cares for patients with chronic renal failure who are treated by dialysis and by transplantation. They exemplify the citation, "Chronic diseases now play an increasingly important role in the practice of medicine."<sup>2</sup>They have a chronic problem that requires medical supervision over a very long period of time; many organ systems are affected and many new events,
Blue Moon
Authors: Ted Branstetter
Journal: JAMA (1992)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
DESTINY OF CASE-BOOKS.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Progress Toward Poliomyelitis Eradication—Bangladesh, 1995-1997
Journal: JAMA (1998)

As a member of the World Health Assembly, in 1988 Bangladesh adopted the goal of poliomyelitis eradication by 2000. To achieve this goal, Bangladesh has implemented the following strategies recommended by the World Health Organization (WHO): 1) achieving high routine coverage with at least three doses of oral poliovirus vaccine (OPV3) among infants aged <12 months; 2) conducting National Immunization Days (NIDs) to interrupt widespread circulation of poliovirus; 3) establishing sensitive systems for surveillance of polio cases and poliovirus that rely on acute flaccid paralysis (AFP) reporting; and 4) carrying out "mopping-up" campaigns to eliminate the last foci of poliovirus transmission. This report describes progress toward polio eradication in Bangladesh during 1995-1997. The findings suggest that polio cases and wild poliovirus circulation are declining rapidly and that polio-eradication activities have effectively assisted in addressing other health priorities in Bangladesh.
Abstracts Pt.50
Authors: Aditya Gupta, Andrea Cherman, John Scimeca, Monya Sigler, Thomas Stephens, M Fujimura, V Guerreiro, F Pa, A Salgado, J Savioli, Otavio Macedo, F Pa ´dua, J Am, Acad Dermatol, Catarina Capela, Marina Odo, Lilian Odo, Carlos Cuce
Journal: Journal of the American Academy of Dermatology (2006)
Septic Abortion
Authors: Benjamin Tenney, A. Brian Little, Emile Wamsteker
Journal: New England Journal of Medicine (1957)

IT is necessary to reappraise the clinical importance of septic processes in gynecology since the emergence of antibiotic-resistant strains of bacteria. Septic abortions are not often seen in general practice but form a considerable portion of the admissions to a large city-hospital service. This study is to evaluate, once again, the clinical management and prognosis of septic abortion, and to determine if present concepts of therapy are valid.The diagnosis of septic abortion is difficult to make with certainty. In a patient who is pregnant, bleeding and febrile, the admission diagnosis is usually septic abortion. In approximately a third of . . .
SickleInAfrica
Authors: Julie Makani, Raphael Z Sangeda, Obiageli Nnodu, Victoria Nembaware, Alex Osei-Akoto, Vivian Paintsil, Emmanuel Balandya, Jill Kent, Lucio Luzzatto, Solomon Ofori-Acquah, Olofunmi I Olopade, Kisali Pallangyo, Irene K Minja, Mario Jonas, Gaston K Mazandu, Nicola Mulder, Kwaku Ohene-Frempong, Ambroise Wonkam
Journal: The Lancet Haematology (2020)
Abstract 3990: Circulating tumor DNA assessed through amplicon-based next-generation sequencing and its clinical application
Authors: Hitoshi Zembutsu, Hiroki Osumi, Eiji Shinozaki, Kensei Yamaguchi, Masato Ozaka, Takashi Sasaki, Marie Muramatsu, Naoki Sasahira
Journal: Cancer Research (2019)

Abstract Circulating tumor DNA (ctDNA) studies focusing on only one or a few genes to monitor the disease progress or treatment response are unlikely to find its clinical significance. Hence, the development of cell-free DNA (cfDNA) panel covering hundreds of mutation hotspots is important for the establishment of clinically practical ctDNA detection system. We enrolled 101 patients with metastatic colorectal cancer (mCRC) who received chemotherapy. Amplicon-based genomic profiling of 14 genes, which are commonly mutated in CRC, in plasma by next-generation sequencing (NGS) was performed to evaluate the feasibility of this assay, and was compared with their clinical parameters and RAS status in matched tissue samples. Somatic mutations of the 14 genes in plasma cfDNA were detected in 88 patients (87.1%) with mCRC. Mutations in TP53, KRAS and APC genes were detected in 70 (69.3%), 39 (38.6%) and 24 (23.7%) patients, respectively. Mutant allele frequencies in cfDNA were significantly associated with metastasis (liver, P=0.00004, lymph node, P=0.008, number of metastatic organs, P=0.0006), tumor markers (CEA, P=0.000007, CA19-9, P=0.006, LDH, P=0.00001), and tumor diameter (maximum, P=0.00002, sum of diameter, P=0.00009). The overall concordance rate of RAS status between ctDNA and matched tissue was 77.2% (78/101). Furthermore, we enrolled 76 patients with stage lV pancreatic cancer, and their genomic profiling of 14 genes in plasma were performed to evaluate the feasibility of the cfDNA panel. We observed that patients with lower ctDNA level showed significantly longer overall survival (P=0.00000026). Our data confirmed that mutant allele in cfDNA can be sensitively detected by amplicon-based NGS system. These results suggest that ctDNA could be a novel diagnostic biomarker to monitor changes in mutational status and tumor burden in patients with mCRC, and a predictive marker for survival in patients with advanced pancreatic cancer. Citation Format: Hitoshi Zembutsu, Hiroki Osumi, Eiji Shinozaki, Kensei Yamaguchi, Masato Ozaka, Takashi Sasaki, Marie Muramatsu, Naoki Sasahira. Circulating tumor DNA assessed through amplicon-based next-generation sequencing and its clinical application [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 3990.
Highlights
Journal: JAMA Internal Medicine (2018)

Alcohol-Related Nurse Care ManagementBradley and colleagues conducted a randomized clinical trial to test whether 12 months of alcohol care management improved drinking outcomes among patients with or at high risk for alcohol use disorders compared with usual care.Between October 11, 2011, and September 30, 2014, the study enrolled 304 outpatients who reported heavy drinking (Ն4 drinks per day for women and Ն5 drinks per day for men) who were subsequently allocated to an intervention or usual care.Results demonstrated that the intervention did not decrease heavy drinking or related problems despite increased engagement in alcohol-related care. Cardiovascular Safety of Smoking Cessation Medications 622For this double-blind, randomized, triple-dummy, placebo-and active-controlled trial-the Evaluating Adverse Events in a Global Smoking Cessation Study (EAGLES)-Benowitz and colleagues examined the relative cardiovascular safety risk of varenicline, bupropion, and nicotine patch in 8058 smokers.The incidence of cardiovascular events during treatment and follow-up was low and did not differ significantly by treatment, and no evidence that the use of smoking cessation pharmacotherapies increased the risk of serious cardiovascular adverse events during or after treatment was observed.
L'évolution de la lutte contre la syphilis: Un bilan de 25 ans Nancy 1907-1932
Journal: JAMA (1934)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Misplaced.
Journal: JAMA (1884)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 5398: Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) Supplementation, but not α-Linolenic Acid, Elevates Plasma Adiponectin Concentration and Prevents Pressure Overload Induced Ventricular Dysfunction and Remodeling
Authors: Monika K Duda, Wenhong Xu, Anselm Tintinu, Karen M O’Shea, William C Stanley
Journal: Circulation (2008)

Coronary disease is reduced by intake of the ω-3 polyunsaturated fatty acids (ω-3PUFA) EPA and DHA. Recent evidence suggest EPA+DHA may also prevent development of heart failure. We previously showed that intake of fish oil rich in EPA+DHA up-regulates expression and plasma levels of adiponectin, a cardioprotective adipose-derived hormone. We examined the effects of dietary EPA+DHA on plasma adiponectin levels and development of left ventriclular (LV) dysfunction and remodeling in response to pressure overload induced by abdominal aorta banding. Rats were fed either a standard chow or diets supplemented with EPA+DHA from fish oil at 0.7%, 2.3% or 7% of energy intake. LV volumes were measured by echo. On the standard diet banding increased LV mass by 38%, LV end diastolic volume by 29%, and end diastolic volume by 101% compared to sham (p&lt;0.05). EPA+DHA supplementation increased plasma adiponectin concentration in a dose dependent manner (see Fig. ), and prevented the increases in LV end diastolic volume and end systolic volume (p&lt;0.05). Adiponectin levels were negatively correlated with LV end systolic and diastolic volumes (r=−0.78 and −0.71, respectively; p&lt;0.001). The protective effect of adiponectin has been linked to AMPK activation and/or inhibition of pro-growth Akt, however there were no differences in AMPK or Akt activation by western blot. A parallel series of rats were fed with α-linolenic acid, a ω-3PUFA from flaxseed, over a similar dose range, and showed no increase in adiponectin or prevention of LV pathology. In conclusion, supplementation with EPA+DHA prevented LV remodeling and dysfunction, which was strongly associated with an elevation in plasma adiponectin.
CUMBERING THE RECORD.
Journal: JAMA (1898)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
EDITORIAL.
Authors: U. O. B. Wingate
Journal: JAMA (1893)

Milwaukee, March 11, 1893. It is necessary for all those who are to read or present papers at our meeting, to send a copy of the same to the Secretary of the Section in which the paper is to be presented, and in time for him to forward to the Chairman of the Committee of Arrangements the title of said paper fully one month before the annual meeting, as required by the By-laws. I shall be obliged to keep strictly to this provision of the By-laws and no title of any paper can be published in our program unless it reaches me through the Secretary of the Section in which it is to be read by May 6. I find that the Secretaries of the Sections desire to know what papers are to be presented in their Sections, and I think that is proper and right, and that the titles
Insufficient Anaesthesia
Authors: V. Russell
Journal: BMJ (1950)

<b>OBJECTIVE:</b> To describe Sir Charles Symonds numerous landmark discoveries in areas such as traumatic brain injury, subarachnoid hemorrhage, epilepsy, headache, encephalitis lethargica, and neuropsychiatry. <b>BACKGROUND:</b> Sir Charles Symonds exemplifies the neurologist of his time, with depth and breadth of knowledge in an extraordinary number of neurologic and psychiatric conditions. <b>DESIGN/METHODS:</b> Literature review (OvidMEDLINE) and autobiographic and biographic sources of information were researched. <b>RESULTS:</b> Sir Charles Symonds neurologic training began at the National Hospital, Queen Square where he was taught by Gordon Holmes and Kinnier Wilson. He later spent time studying psychiatry under Adolf Meyer at the Johns Hopkins Hospital and neurosurgery under Harvey Cushing at the Peter Bent Brigham Hospital. Under the tutelage of Cushing, Symonds was the first to document the importance of intracranial aneurysms as a cause of subarachnoid hemorrhage and paved the way for clinicians to diagnose the condition before death. His clinical interest in the physical and psychological effects of head trauma was born out of his many years of service in the military. From these experiences, he understood the necessity for psychologists and neurologists to work together in the treatment of these patients. Later, he created a Hospital for Head Injuries at Oxford University. Symonds9 knowledge of such a broad number of diseases for which he proficiently wrote and made significant scientific discoveries is truly astonishing. <b>CONCLUSIONS:</b> Unique to Symonds was his ability to integrate sound clinical and scientific knowledge with his creative spirit and in doing so, challenging the current conceptualization of many neurologic conditions. This was fostered by his broad clinical experiences and his mentorship with leaders in the field such as Hurst, Cushing, Wilson, and Lord Brain. <b>Disclosure:</b> Dr. Thakur has nothing to disclose. Dr. Ropper has nothing to disclose.
Impact of Organochlorine Contamination on Levels of Sex Hormones and External Morphology of Common Snapping Turtles (Chelydra serpentina serpentina) in Ontario, Canada
Authors: Shane R. de Solla, Christine A. Bishop, Glen Van Der Kraak, Ronald J. Brooks
Journal: Environmental Health Perspectives (1998)

Recent research has suggested that contaminants in the environment may influence sex differentiation and reproductive endocrine function in wildlife. Concentrations of organochlorine contaminants (total polychlorinated biphenyls, pesticides) were higher in the blood plasma of snapping turtles from contaminated sites than in those from reference sites. The ratio of the precloacal length to the posterior lobe of the plastron (PPR) is sexually dimorphic in snapping turtles. There were significant reductions in the PPR at three contaminated sites versus two reference sites. The magnitude of the response was such that a significantly higher proportion of PPRs of males from a contaminated site (Cootes Paradise) overlapped with those of females than PPRs of males from a reference site (Lake Sasajewun). Observers can incorrectly identify the sex of turtles at the contaminated site based on secondary sexual characteristics alone. Unlike the changes to the morphology, there were few changes in 17 beta-estradiol or testosterone levels, and where differences occurred, there was more variation among reference sites than between the reference and contaminated sites. Our results suggest that environmental contaminants may affect sexually dimorphic morphology in snapping turtles without affecting circulating testosterone or estrogen levels in the adults.
Gastrointestinal Bleeding
Authors: T A Marek
Journal: Endoscopy (2001)

There was a significant increase in the number of abstracts dealing with the topic of gastrointestinal bleeding that were presented at the Digestive Diseases Week (DDW) this year, making the task of selecting abstracts for detailed review more difficult. Priority has been given here to papers accepted for oral presentations, large meta-analyses, randomized controlled trials involving larger numbers of patients, descriptions of new techniques, and abstracts presenting data significantly differing from what is commonly known.
Errors Three Re Isoenzymes
Journal: JAMA (1968)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal