tbuckley/cabot-search huggingface dataset:
Annals of Surgery, Philadelphia
Journal: JAMA (1970)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
AGGLUTINATION OF TUBERCLE BACILLI AND NEW TUBERCULIN.
Journal: JAMA (1902)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Manuscripts Approved for JNCI, August 1 to September 1, 1970
Journal: JNCI Journal of the National Cancer Institute (1970)

Journal Article Manuscripts Approved for JNCI, August 1 to September 1, 1970 Get access JNCI: Journal of the National Cancer Institute, Volume 45, Issue 4, October 1970, Pages 843–844, https://doi.org/10.1093/jnci/45.4.843 Published: 01 October 1970
MATERNAL IMPRESSIONS.
Journal: JAMA (1999)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Postexercise Peril
Authors: Joel E. Dimsdale
Journal: JAMA (1984)

Postexercise cardiac morbidity is noted both in the exercise testing laboratory and in the field, but the physiology of this phenomenon has been unclear. Plasma catecholamine levels were studied in ten healthy men at each work load during exercise testing and during the recovery period after exercise. Both norepinephrine and epinephrine levels increased in response to exercise, although the response was much more noteworthy for norepinephrine. In the recovery period after exercise, both catecholamine levels continued to increase, with the norepinephrine level increasing tenfold over baseline. Such increases may have profound effects, particularly for subjects with preexisting coronary disease. (<i>JAMA</i>1984;251:630-632)
Muddling through isn't enough
Authors: R. H. Murray
Journal: JAMA (1975)

THIS country's unexpressed health policy is, and really always has been, muddling through—a strategy of free-floating expediency, responding capriciously to the pressures and passing fancies of the health establishment, social zealots, health planners, and budgeteers. It is practiced regularly by politicians who have a penchant for brush-fire planning and hastily designed programs that serve to cover over health problems with boundless money and immature ideas. It is the favorite method of pragmatic administrators and bureaucrats who must manage complicated health organizations without goals or guidelines—where the "right" decision is not known or even knowable, or if knowable might not be implementable. This policy has caused factionalism to flourish and made planning impotent. One of its most visible consequences is the endless output of new health legislation—a kaleidoscopic jumble of mismatched efforts. Another is an ever-expanding bureaucracy, since established programs never die and hardly ever fade away. The most unsettling outcome
Dupilumab in Moderate-to-Severe Atopic Dermatitis With or Without Comorbid Allergic Rhinitis: Pooled Analysis of 2 Randomized Phase 3 Trials (LIBERTY AD SOLO 1 &amp; 2)
Authors: Diamant Thaçi, Thomas R.M. Bieber, Neil M.H. Graham, Gianluca Pirozzi, Bolanle Akinlade, Laurent Eckert, Abhijit Gadkari, Marius Ardeleanu
Journal: Journal of Allergy and Clinical Immunology (2018)
Erratum: Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease.
Authors: M Teresa Grande, Berta Sánchez-Laorden, Cristina López-Blau, Cristina A De Frutos, Agnès Boutet, Miguel Arévalo, R Grant Rowe, Stephen J Weiss, José M López-Novoa, M Angela Nieto
Journal: Nature Medicine (2016)
Setting health care priorities in Oregon. Cost-effectiveness meets the rule of rescue
Authors: D. C. Hadorn
Journal: JAMA (1991)

The Oregon Health Services Commission recently completed work on its principal charge: creation of a prioritized list of health care services, ranging from the most important to the least important. Oregon's draft priority list was criticized because it seemed to favor minor treatments over lifesaving ones. This reaction reflects a fundamental and irreconcilable conflict between cost-effectiveness analysis and the powerful human proclivity to rescue endangered life: the "Rule of Rescue." Oregon's<i>final</i>priority list was generated without reference to costs and is, therefore, more intuitively sensible than the initial list. However, the utility of the final list is limited by its lack of specificity with regard to conditions and treatments. An alternative approach for setting health care priorities would circumvent the Rule of Rescue by carefully defining necessary indications for treatment. Such an approach might be applied to Oregon's final list in order to achieve better specificity. (<i>JAMA</i>. 1991;265:2218-2225)
Deaths
Journal: JAMA (1973)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Evaluation of computer-acquired patient histories
Authors: J. H. Grossman
Journal: JAMA (1971)

A system for automated collection of patients' medical histories has been developed. The patient is interviewed by the computer system and a printed summary of the interview is made available to the physician. During the past two years, this system has been evaluated with respect to patient attitudes, physician attitudes, and completeness and accuracy of the data. Patients have had a favorable attitude towards the computer system; physicians' attitudes are mixed. The automated technique records more items than are found in physician-recorded medical records, and there is a high degree of agreement when the data are compared to those of physician-recorded histories. The final assessment of the potential value and utility of such a technique must be considered in light of the particular care environment in which it is to be applied.
Cocaine use, risk taking, and fatal Russian roulette
Authors: P. M. Marzuk
Journal: JAMA (1992)

<h3>Objective.</h3> —To examine the association between recent cocaine use and risk taking, particularly in the form of playing Russian roulette, a paradigm for extreme risk-taking behavior. <h3>Design.</h3> —A case-control study. <h3>Cases and Controls.</h3> —The prevalence of cocaine use among all Russian roulette fatalities (N=14) was compared with a demographically similar, randomly selected sample (N=54) of all suicides by handgun during a contemporaneous 4-year period in New York City, NY. <h3>Results.</h3> —Recent use of cocaine, the most common drug found at autopsy, was detected in 64% of Russian roulette fatalities and in 35% of the control group (<i>P</i>&lt;.05). All Russian roulette fatalities were male and usually young and unemployed. Blacks and Hispanics accounted for 80% of all cases and were overrepresented compared with their numbers in the general population. <h3>Conclusion.</h3> —In some populations cocaine may be associated with life-threatening risk-taking behaviors. (<i>JAMA</i>. 1992;267:2635-2637)
The Medical Management of AIDS
Authors: Jerry D. Smilack
Journal: JAMA (1997)

Imagine being given an assignment to develop a book that is to provide clinicians with the latest knowledge concerning human immunodeficiency virus (HIV) infection and its consequences—immunodeficiency and opportunistic infections—as well as their treatment and prevention. Such a project could easily result in a book of 1000 pages, enough to strain the limits of the human body to carry from home to office. To accomplish the task in a handy, manageable, and readable volume of half that size is exactly what Sande and Vol-E berding have once again done. The secret is to enlist the aid of clinician-academicians who have seen the acquired immunodeficiency syndrome (AIDS) epidemic from its very beginnings in 1981 and have followed it through to to-day's domineering presence. Ask these clinicians to put on paper what is really key in managing HIV-infected individuals and to update their material frequently. The result is this
Cytochrome b deficiency in an autosomal form of chronic granulomatous disease. A third form of chronic granulomatous disease recognized by monocyte hybridization
Journal: Journal of Clinical Investigation (1985)

Regarding the terminology used in this paper, neither monocytes nor fused monocytes are able to replicate in vitro.Fusion of nuclei was not observed during 1 wk of maintenance culture.Therefore, the fused monocytes should be considered heterokaryons rather than hybrids.
Rape and subsequent seroconversion to HIV.
Authors: S. Murphy, V. Kitchen, J. R. Harris, S. M. Forster
Journal: BMJ (1989)

Infection with HIV may be transmitted to a victim of sexual assault.' 2 Seroconversion to HIV occurred in the three months after a rape in a woman who had no other identifiable risk factors for HIV infection. Case reportIn Mav 1987 a 24 year old woman was examined and
The parents' journey: continuing a pregnancy after a diagnosis of Patau's syndrome
Journal: BMJ (2005)

encouraged to exercise choice and consumer power by moving between these integrated care organisations, rather than through their choice of secondary or tertiary care providers.To prevent superpractices creaming off low risk, low cost patients, the NHS would need to develop a more sophisticated risk adjusted resource allocation formula.This could use the data now routinely collected at practice level by the new quality outcomes framework-for example, smoking status, body mass index, and blood pressure.National bodies will still be required to assess performance and conduct other monitoring, and both national and regional bodies would provide the technical and infrastructure support for assessing needs and setting priorities.Methods and criteria for managing scarcity and improving services could also be developed at this level but adapted locally with community and partnership agencies.
Medical Journal of Australia, Sydney
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A Decade of Progress in the Rh Blood-Group System
Authors: Alan Richardson Jones, Louis K. Diamond, Fred H. Allen
Journal: New England Journal of Medicine (1954)

THE importance of the Rh factor is now well appreciated by both the physician and the layman. Understanding of the basic concept of isoimmunization by blood transfusion or by pregnancy requires only the knowledge that blood may be classified as "Rh positive" and "Rh negative." This was illustrated by Diamond's1 review in 1945, which described all the clinical manifestations associated with intragroup incompatibility of mother and fetus, or donor and recipient. After eight years it is scarcely possible to add anything to the essential principles on which understanding of the pathology of these conditions is based. But a great deal . . .
From the NIH. Magnetic device tests for iron overload
Authors: J. N. Fordham
Journal: JAMA (1985)

Patients with disorders such as Cooley's anemia (severe β-thalassemia) or hereditary hemochromatosis have elevated levels of total body iron that must be treated. John Harris, MD, and Gary Brittenham, MD, at Case Western Reserve University School of Medicine, Cleveland, have developed a magnetic device that can noninvasively determine body iron content. The instrument, known as a superconducting quantuminterference device (SQUID) susceptometer, will allow earlier identification than is now possible of patients at risk of iron overload. This device is believed to be the only instrument of its kind in the world at present. Its developers have received grant support from the National Institute of Arthritis, Diabetes, and Digestive and Kidney Diseases, Bethesda, Md, a part of the National Institutes of Health. The normal adult body contains about 4 g of iron, of which 3 g are involved in oxygen transport and storage. Approximately 1 g is in two specialized proteins,
Use and abuse of intravenous solutions
Authors: D. G. Vidt
Journal: JAMA (1975)

THIS REVIEW of the uses and dangers of intravenous fluid therapy is part of the Drug Spotlight Program of the American Society for Clinical Pharmacology and Therapeutics. It is hoped that it will stimulate hospital pharmacy and therapeutics committees to review critically the use of intravenous fluids in their institutions. <h3>Purposes of Fluid Therapy</h3> Establishing and maintaining adequate composition of fluids and electrolytes in patients who suffer from a variety of diseases has become one of the most important functions of modern hospitals. Therapy of disturbed metabolism of fluids and electrolytes is also one of the most frequently misunderstood and most difficult problems for clinicians who are not accustomed to thinking in quantitative terms and who may focus on only one aspect of a complex situation. Intravenous fluids are used (1) to maintain normal body composition when normal food or fluid intake is impossible and (2) to correct acute or
Contents
Authors: Cecilia Lee, Aneesha Morris, Russell Van Gelder, Aaron Lee, Michael Repka, Trevano Dean, Elizabeth Lazar, Kimberly Yen, Phoebe Lenhart, Sharon Freedman, Denise Hug, Bahram Rahmani, Serena Wang, Raymond Kraker, David Wallace, Eye Disease, So Goto, Naoyuki Maeda, Shizuka Koh, Kazuhiko Ohnuma, Kenichi Hayashi, Toru Noda, Kohji Nishida, Massimo Busin, Claudia Breda, Marina Bertolin, Cristina Bovone, Diego Ponzin, Stefano Ferrari, Vanessa Barbaro, Mostafa Elbadawy, Kunal Dansingani, Lorah Perlee, Sara Hamon, May Lee, Vinnie Shah, Richard Spaide, John Sorenson, James Klancnik, Lawrence Yannuzzi, Irene Barbazetto, Michael Cooney, Michael Engelbert, Christine Chen, Alex Hewitt, K Freund, Arash Maleki, Robert Swan, Andres Lasave, Lina Ma, C Foster, Pcr Quantification, D Folliculorum, Juan Sánchez España, Alberto Abreu, Alejandro Álvarez López, Ligia Naranjo González, María González Gallego, Carlos Hidalgo Grass, Carlos Frutos, Parul Chawla Gupta, Jagat Ram, Andrzej Grzybowski
Journal: Ophthalmology (2016)
Environmental Influences on Epigenetic Regulation
Authors: Frederick Tyson, Jerrold Heindel
Journal: Environmental Health Perspectives (2005)

E pigenetics refers to the study of gene silencing and non-Mendelian inheritance of traits.By controlling the expression of key genes and associated pathways, epigenetics provides an elegant mechanism for time and tissue-specific expression of key biologic molecules across the life span.The available data support the notion that epigenetic processes can be influenced by both exogenous and endogenous factors.Specific agents in the areas of nutrition, environmental chemicals, stressors, and pharmaceutical agents have been shown to affect the epigenetic state.Few data are available to address the potential relationship between such changes and adverse functional outcomes.The role of epigenetics in the regulation of normal development as well as the impact of exogenous influences (e.g., environmental chemicals, stressors, nutrition, drugs) on epigenetic pathways is an emerging area of interest.
The safety of the hepatitis B vaccine. Inactivation of the AIDS virus during routine vaccine manufacture
Authors: D. P. Francis
Journal: JAMA (1986)

In the United States, one hepatitis B vaccine (Heptavax-B) has been licensed for the prevention of hepatitis B virus infections. Even though this vaccine has been shown to be highly effective and well tolerated in controlled trials and has been recommended for use in those at risk for acquiring infection by hepatitis B virus, many individuals have been reluctant to be immunized for fear of contracting acquired immunodeficiency syndrome (AIDS). In this study, we demonstrate that (1) each of the three inactivation steps used in the manufacture of Heptavax-B independently will inactivate the infectivity of high-titered preparations of the AIDS virus; (2) recipients of the hepatitis B vaccine do not develop antibodies to the AIDS virus; (3) the hepatitis B vaccine does not contain detectable levels of nucleic acids related to the AIDS virus. These observations clearly demonstrate that vaccination with the currently available hepatitis B vaccine poses no demonstrable risk for acquiring AIDS. (<i>JAMA</i>1986;256:869-872)
Preventive and therapeutic effects in rats of hepatocyte growth factor infusion on liver fibrosis/cirrhosis
Authors: Y Matsuda, K Matsumoto, A Yamada, T Ichida, H Asakura, Y Komoriya, E Nishiyama, T Nakamura
Journal: Hepatology (1997)

Liver fibrosis/cirrhosis is characterized by hyper-accumulation of fibrous tissue components and is commonly observed in later or terminal states of chronic hepatic diseases. In ongoing work, we found that the administration of human recombinant hepatocyte growth factor (hrHGF) suppressed the onset of liver fibrosis/cirrhosis in several distinct models and accelerated the recovery from liver fibrosis/cirrhosis in rats. Repeated administration of porcine serum for 10 weeks to rats induced liver fibrosis without any accompanying hepatocellular injuries; in addition, the intravenous (i.v.) administration of hepatocyte growth factor (HGF) to these rats suppressed increases in fibrous components and hydroxyproline contents in the liver, thus preventing the onset of liver fibrosis. Repeated administration of dimethylnitrosamine (DMN) for four weeks induced liver cirrhosis, as characterized by the hyper-accumulation of fibrous components, infiltration of mononuclear leukocytes, and hepatic dysfunction. When HGF was injected daily for four weeks along with DMN-treatment, the onset of DMN-induced hepatic fibrosis/cirrhosis was suppressed; the numbers of infiltrating mononuclear cells, fibrous tissue components, and hydroxyproline content in the liver were decreased. When HGF was injected for two weeks following four weeks of DMN-treatment, HGF accelerated the recovery from liver cirrhosis and prevented death due to hepatic dysfunction. Likewise, HGF-injection suppressed the onset of liver fibrosis, when liver fibrosis had been induced by long-term treatment with carbon tetrachloride (CCl 4 ). Thus, the administration of HGF holds great promise for treating subjects with liver fibrosis/cirrhosis as a result of chronic hepatic injury.