tbuckley/cabot-search huggingface dataset:
Myocardial Reinfarction After Anesthesia and Surgery
Authors: Petter A. Steen, John H. Tinker, Sait Tarhan
Journal: JAMA (1978)

During the years 1974 and 1975 at our institution, 587 patients who had suffered previous myocardial infarctions underwent anesthesia and surgery. Thirty-six (6.1%) had a reinfarction and 25 (69%) died. Patients operated on within three months of the previous infarction had a 27% reinfarction rate. This decreased to 11% if the infarct had occurred three to six months previously and stabilized at 4% to 5% if the interval was more than six months. Risk factors associated with significantly increased reinfarction rates included preoperative hypertension, intraoperative hypotensive episodes, and noncardiac thoracic or upper abdominal operations of more than three hours' duration. Time under anesthesia was strikingly correlated with reinfarction rates in the entire group. Postoperative intensive care unit admission did not significantly affect the reinfarction rate, nor did diabetes, angina, patient age or sex, or site of the previous myocardial infarction. (<i>JAMA</i>239:2566-2570, 1978)
<i>Epilepsy and other Chronic Convulsive Diseases: Their Causes, Symptoms and Treatment</i>. By Sir William R. Gowers, M. D., F. R. C. P., F. R. S., Consulting Physician to University College Hospital, etc., etc. Second edition. ( Philadelphia, P. Blakiston's Sons &amp; Co., 1012 Walnut St., 1901.)
Journal: American Journal of Psychiatry (1901)
AUSTRALIA
Journal: JAMA (1933)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Anticholinergics in the treatment of children and adults with acute asthma: a systematic review with meta-analysis
Authors: G J Rodrigo, J A Castro-Rodriguez
Journal: Thorax (2005)

<b>Background:</b> Current guidelines recommend the use of a combination of inhaled β<sub>2</sub> agonists and anticholinergics, particularly for patients with acute severe or life threatening asthma in the emergency setting. However, this statement is based on a relatively small number of randomised controlled trials and related systematic reviews. A review was undertaken to incorporate the more recent evidence available about the effectiveness of treatment with a combination of β<sub>2</sub> agonists and anticholinergics compared with β<sub>2</sub> agonists alone in the treatment of acute asthma. <b>Methods:</b> A search was conducted of all randomised controlled trials published before April 2005. <b>Results:</b> Data from 32 randomised controlled trials (n = 3611 subjects) showed significant reductions in hospital admissions in both children (RR = 0.73; 95% CI 0.63 to 0.85, p = 0.0001) and adults (RR = 0.68; 95% CI 0.53 to 0.86, p = 0.002) treated with inhaled anticholinergic agents. Combined treatment also produced a significant increase in spirometric parameters 60–120 minutes after the last treatment in both children (SMD = −0.54; 95% CI −0.28 to −0.81, p = 0.0001) and adults (SMD = −0.36; 95% CI −0.23 to −0.49, p = 0.00001). <b>Conclusions:</b> This review strongly suggests that the addition of multiple doses of inhaled ipratropium bromide to β<sub>2</sub> agonists is indicated as the standard treatment in children, adolescents, and adults with moderate to severe exacerbations of asthma in the emergency setting.
Hepatology
Authors: Loreta Kondili, Federica Romano, Francesca Rolli, Matteo Ruggeri, Stefano Rosato, Maurizia Brunetto, Anna Zignego, Alessia Ciancio, Alfredo Leo, Giovanni Raimondo, Carlo Ferrari, Gloria Taliani, Guglielmo Borgia, Teresa Santantonio, Pierluigi Blanc, Giovanni Gaeta, Antonio Gasbarrini, Luchino Chessa, Elke Erne, Erica Villa, Donatella Ieluzzi, Francesco Russo, Pietro Andreone, Maria Vinci, Carmine Coppola, Liliana Chemello, Salvatore Madonia, Gabriella Verucchi, Marcello Persico, Massimo Zuin, Massimo Puoti, Alfredo Alberti, Gerardo Nardone, Marco Massari, Giuseppe Montalto, Giuseppe Foti, Maria Rumi, Maria Giovanna Quaranta, Americo Cicchetti, Antonio Crax, Stefano Vella
Journal: Hepatology (2006)

on behalf of the PITER Collaborating Group
Philippe Pinel of France: Science, Philosophy, Courage, Humanity, all in one person.
Journal: JAMA (1898)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Psoriderm
Authors: Napier Thorne
Journal: British Journal of Dermatology (1965)

Journal Article Psoriderm Get access Napier Thorne Napier Thorne London Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 77, Issue 2, 1 February 1965, Page 112, https://doi.org/10.1111/j.1365-2133.1965.tb14611.x Published: 01 February 1965
Phenylguanine found in urine after benzene exposure.
Authors: K H Norpoth, G Müller, C Schell, E Jorg
Journal: Environmental Health Perspectives (1996)

Comparative investigations with synthetic N7-phenylguanine were carried out to clarify whether this compound is eliminated via the urine of rats as a benzene-derived nucleic acid adduct. As sensitive methods for detecting trace amounts of the compound, gas chromatography-mass spectroscopy, high performance liquid chromatography, and two immunoassays (enzyme-linked immunosorbent assay and fluoroimmunoassay) with appropriate monoclonal antibodies were used. The results indicate the excretion of several benzene-related guanine adducts slightly different from N7-phenylguanine that may possibly be hydroxylated. These adducts differ also from (O6-, N2- and C8-phenylguanine, respectively.
Massachusetts Medical Society
Authors: Eliot Hubbard, John Figgis Jewett
Journal: New England Journal of Medicine (1956)

TREASURER'S OFFICEThis year the Committee on Finance has voted to distribute $6,000 to the district societies toward defraying their operating expenses from the surplus in the General Fund at the end of 1955.Members are reminded that the percentage of this sum that is allocated to their own district is determined by the number of dues from that district paid by March 1, 1956. Members who have not paid their dues by this date are automatically removed from the mailing list of the Journal until such dues are paid.COMMITTEE ON MATERNAL WELFAREPuerperal SepsisA twenty-three-year-old primigravida with . . .
Malignolipin in Cancer Diagnosis
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Deaths
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
AN UNUSUAL CASE OF KIDNEY INFECTION
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Virology
Authors: Eli Gold
Journal: JAMA (1986)

Fields'<i>Virology</i>is a comprehensive effort 1,614 pages in length with 64 contributors, all recognized investigators and teachers. The book is a nice blend of basic virology, epidemiology, pathogenesis, immunology, and medical aspects or implications. The authors, many of whom have medical degrees, move effortlessly from the molecular biology of viral agents to their clinical behavior. The result is a comprehensive, current, and carefully documented text, which will serve as an authoritative reference for graduate students, medical students, physicians, laboratory workers, and others interested in the biology of animal viruses. I was struck by the clarity, organization, and content of the individual chapters. Each begins with a clear statement of purpose; terms are defined, basic biology illustrated, studies critically reviewed, conclusions summarized, and hopes or expectations for the future cautiously presented. This hefty volume has been lying on my desk during the past few weeks. I found it useful when
Epidemic Sore-Throat
Authors: C. Cowdell
Journal: BMJ (1858)

JOVaKALspecial interest attaches to the first case, on account of the roof it gives of the great difficulties wbich may be vanquished by persevernce on the pat of the surgeon, and deterrninstiou on that of the patient.The latter quality was most aon- spicuous in this poor fellow, in whom repeated failures seemed to have no effect in unsettling his purpose, or shaking his con- fidence of ultimate success.It was interesting to observe the perfect healthiness and freedom from adhesions of the tissues *round the opening, in spite of the frequent operations and the acute inflammation and effusion of urine which had followed the accident.The absence also of contraction of the urethra was another very favourable cairumstance.The ultimate oauso of success in Mr. Poliock's case appeared to be the dii-.sion of the prepuce, and the very loose condition of the integu.ment which was obtained by the last operative procedure, and by which the traction on the wound during erection was en- .elyprevented.
The Note-Book of an Electro-Therapist.
Journal: JAMA (1923)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Postlaryngectomy Microstoma
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Mother and child.
Journal: JAMA (1893)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Fibrinolysis
Authors: Liberto Pechet
Journal: New England Journal of Medicine (1965)

Fibrinolytic AssayMany of the present methods for measuring fibrinolytic activity either are too complicated to be applicable clinically or, if simple, lack sensitivity. Further difficulties stem from the lability of both plasmin and the blood activator. Since glass in conjunction with factor XII (Hageman) enhances fibrinolysis10 collection of blood in uncoated glassware may result in spuriously high fibrinolytic activity. Heparin, if used as an anticoagulant, may also influence fibrinolysis (as discussed below). Hemolysis, too, may cause increased fibrinolytic activity.For the estimation of overall fibrinolytic activity either body fluids or artificial reagents are admixed with various substrates.97 Free circulating . . .
Abstract 3472: The role of mutant p53 R248W in oral squamous cell carcinoma
Authors: Mayu Enaka, Masako Nakanishi, Yasuteru Muragaki
Journal: Cancer Research (2019)

Abstract TP53 is the most commonly mutated gene in oral squamous cell carcinoma (OSCC). It is known that mutant p53 has not only loss of function but gain of function. Cytokeratin 17 (K17) has been shown to promote tumorigenesis and aggressiveness in OSCCs and other various carcinomas. Although p53 reportedly induces K17 transcription by irradiation, the molecular interaction between p53 and K17 in OSCCs remains unknown. To address this issue, we investigated the relationship between p53 and K17 using SAS cells with nonsense mutation and Ca9-22 cells with R248W mutation in the TP53 gene. Western blot and immunohistochemistry showed higher K17 expression in SAS cells and virtually no K17 expression in Ca9-22 cells, suggesting negative correlation between p53 and K17 expression. ChIP analysis revealed that p53 bound specifically to the tentative p53 binding site in the promoter region of the K17 gene. Unexpectedly, however, overexpression of wild-type (wt) p53 did not suppress K17 expression in SAS cells, whereas knock down of mutant (mt) p53 significantly upregulated K17 expression in Ca9-22 cells, raising a possibility that only R248W mtp53 suppresses K17 expression. Furthermore, overexpression of wtp53 and R248Q mtp53 did not suppressed K17 expression in Ca9-22 cells with knock down of p53, whereas R248W mtp53 overexpression clearly showed suppression of K17. Taken together, R248W mtp53 acts as a direct transcriptional repressor of K17 in OSCCs, reducing aggressiveness of the carcinoma cells. Citation Format: Mayu Enaka, Masako Nakanishi, Yasuteru Muragaki. The role of mutant p53 R248W in oral squamous cell carcinoma [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 3472.
Trypan Blue
Authors: Malini M. Gandhi
Journal: JAMA (2019)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Omission of Percent Sign
Journal: JAMA (1990)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal