tbuckley/cabot-search huggingface dataset:
Measures Used in the Prevention and Treatment of Cardiac Arrhythmias
Authors: Arthur J. Linenthal, A. Stone Freedberg
Journal: New England Journal of Medicine (1949)

Quinidine (and Other Cinchona Alkaloids)Quinidine is of recognized value in the prevention and treatment of various cardiac arrhythmias, such as paroxysmal ventricular tachycardia and paroxysmal auricular fibrillation. However, there is considerable disagreement about the exact indications and contraindications, the nature and frequency of toxic reactions, the routes of administration and the dosage schedules of the drug. Since there is so much confusion surrounding the use of quinidine, the pertinent available information has been assembled and is discussed in some detail. Physiologic Disposition Knowledge of the fate of quinidine in man has been obtained by sensitive, accurate and specific analytical . . .
Advanced Dementia
Authors: Susan L Mitchell
Journal: New England Journal of Medicine (2015)

An 89-year-old male nursing home resident with a 10-year history of Alzheimer's disease presents with a temperature of 38.3°C, a productive cough, and a respiratory rate of 28 breaths per minute.Nurses report that for the past 6 months he has been coughing at breakfast and having trouble swallowing.He has profound memory deficits, no longer recognizes his daughter (who is his health care proxy), is bedbound, is able to mumble a couple of words, and is unable to perform any activities of daily living.The nurse asks whether he should be hospitalized.How should this patient be evaluated and treated? THE CLINICAL PROBLEMIn 2014, Alzheimer's Disease Affected Approximately 5 Million Persons in the United States, a number that is projected to increase to approximately 14 million by 2050. 1 In 2011, it was the sixth leading cause of death in the United States. 2 Population-based studies estimate that 600,000 Americans with Alzheimer's disease died in 2010. 3The median survival after diagnosis ranges from 3 to 12 years, 4 with patients spending most of that time in the severest stage. 5Nursing homes are the most common sites of death [5][6][7] and are thus important for terminal care.Dementia is a progressive, incurable illness.In patients with advanced dementia, the final year of life is characterized by a trajectory of persistently severe disability. 8Stage 7 on the Global Deterioration Scale (ranging from 1 to 7, with higher stages indicating worse dementia) provides a useful description of the features of advanced dementia, 9 including profound memory deficits (e.g., inability to recognize family members), minimal verbal abilities, inability to ambulate independently, inability to perform any activities of daily living, and urinary and fecal incontinence.
Editorial: The rival world.
Journal: BMJ (1974)

as 0-0004 iiU/ml and seems to be similarly sensitive to LATS but with a different time course.Plasma gastrin activity can be bioassayed by the induced stimulation of carbonic anhydrase in the parietal cells ofthe fundus ofthe stomach of guinea-pigs, and the assay has a sensitivity equivalent to 5fg/ml of penta- gastrin.The principles explored by these new, cytochemical tech- niques for hormone bioassay are offundamental importance and we shall see their rapid application to the measurement of many hormones as well as other biologically active substances for which bioassays or radioimmunoassays do not exist or are unsatisfactory.
Diabetes mellitus as a compelling indication for use of renin angiotensin system blockers: systematic review and meta-analysis of randomized trials
Journal: BMJ (2016)

Diabetes mellitus as a compelling indication for use of renin angiotensin system blockers: systematic review and meta-analysis of randomized trialsIn figure 3 the number of participants with myocardial infarction in the RAS blockers group of the STOP-2 trial is missing (
Tourniquet paralysis
Authors: W. K. Hamilton
Journal: JAMA (1967)

Two cases are presented to illustrate a complication which understandably could happen in spite of attention and precautions. The first patient was a man undergoing surgical therapy for Dupuytren's contracture. During performance of axillary block, median nerve paresthesias were elicited. The block was not completely satisfactory and required supplementation with general anesthesia. Postoperatively, the patient complained of numbness in the radial-nerve distribution. This numbness rapidly lessened in the early postoperative period and completely disappeared during a period of postoperative follow-up. Total tourniquet time was 28 minutes, at a gauge pressure of 250 mm Hg. The second patient also had excision of Dupuytren's contracture on the same day, in the same operating room. General anesthesia was used for this patient. Postoperatively, he complained of inability to move his fingers and of numbness of the long, ring, and small fingers. These findings improved rapidly immediately, and returned to normal during the follow-up
Effect of Mean Corpuscular Hemoglobin Concentration on Viscosity
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Leukemia in Utah and radioactive fallout from the Nevada test site. A case-control study
Authors: W. Stevens
Journal: JAMA (1990)

Previous studies reported an association between leukemia rates and amounts of fallout in southwestern Utah from nuclear tests (1952 to 1958), but individual radiation exposures were unavailable. Therefore, a case-control study with 1177 individuals who died of leukemia and 5330 other deaths (controls) was conducted using estimates of dose to bone marrow computed from fallout deposition rates and subjects' residence locations. A weak association between bone marrow dose and all types of leukemia, all ages, and all time periods after exposure was found. This overall trend was not statistically significant, but significant trends in excess risk were found in subgroups defined by cell type, age, and time after exposure. The greatest excess risk was found in those individuals in the high-dose group with acute leukemia who were younger than 20 years at exposure and who died before 1964. These results are consistent with previous studies and with risk estimates for other populations exposed to radiation. (<i>JAMA</i>. 1990;264:585-591)
Changing the system. Implications for physicians
Authors: E. Friedman
Journal: JAMA (1993)

AS HEALTH care reform on the national level moves from the theoretical to the political (as it has already done in a number of states), much of the meat of the matter remains to be determined. Although some actions seem inevitable, others do not. Furthermore, some trends will continue regardless of the direction of reform—unless it takes a truly radical turn, which is unlikely. And along the way are intersections where collisions await: between theory and practice, between the federal government and the states, between the public sector and the private sector, between Congress and the White House (and quite possibly between those two and the US Supreme Court). There is also the element of chance, which has played a major role, at times, in American public policy. The untimely death of Sen John Heinz (R, Pa), resulting in the special election that sent Sen Harris Wofford (D, Pa) back
The Cover
Authors: M. Therese Southgate
Journal: JAMA (1997)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Correction: No money, no treatment
Authors: G Carter, J Pryor
Journal: BMJ (1993)

Two drugs are better than one EDITOR,-We disagree with some of D E Price's views on managing erectile dysfunction in diabetes.'The erectile dysfunction is not always organic in origin since psychogenic factors based on anxiety are as common in diabetic patients as in the general population.A total lack of erections under all circumstances, including during sleep and on waking, may indeed be due to neurogenic impotence, but patients with this are a minority.Patients more commonly complain of a partial erection during sexual activity, which suggests a vasculogenic rather than a neurogenic cause.Intracavernous injection of a vasoactive agent is a simple means of distinguishing vasculogenic from psychogenic and neurogenic impotence.More sophisticated investigations are rarely neces- sary except to investigate the possibility of occult neurological problems or of arterial disease worth treating surgically-that is, in young non-smoking men under 40 who do not have diabetes or hypertension.The use of intracavernous agents for erectile dysfunction has indeed revolutionised the management of this problem, but, at least in theory, papaverine should not now be used alone because of the occurrence of penile fibrosis and priapism.The incidence of these complications is diminished by the addition of phentolamine, but prostaglandin E1 is safer, although a suitable formulation for general use is not yet available.
Management of Hypertension
Authors: Suzanne W. Fletcher
Journal: JAMA (1975)

A randomized controlled trial was conducted in a metropolitan teaching hospital to determine whether improving follow-up of emergency room patients who had hypertension led to improvements in their medical care and blood pressure control. One hundred forty-four patients were randomly assigned into an intervention group and a control group. In the former, a follow-up clerk assisted patients in returning for follow-up care. Eighty-four percent of patients in this group and 63% of control patients returned to the clinic (<i>P</i>&lt;.01). However, five months after the patients' emergency room visits, 51% of patients in the intervention group and 53% of control patients were normotensive. There were more diagnostic and therapeutic measures in the intervention group, but long-term management was similar in both groups. Improvement in follow-up may not by itself lead to blood pressure control among hypertensive patients. (<i>JAMA</i>233:242-244, 1975)
MEDICAL SERVICES TO DEPENDENTS OF SERVICEMEN
Journal: JAMA (1952)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Consensus development conferences
Authors: W. R. Barclay
Journal: JAMA (1978)

The National Institutes of Health (NIH) have initiated a series of consensus development exercises that will take place during 1978 and 1979. The major purpose of these exercises or conferences is to make useful new knowledge concerning the prevention, detection, diagnosis, and treatment of major disease entities available to practicing physicians. In the normal course of events, a substantial time lag occurs between the development of new, valid information by the research community and its widespread application in the provision of medical care. In large measure, this delay is the result of a slow diffusion process that relies on medical journals, professional meetings, courses, textbooks, and interpersonal contacts and lacks, therefore, planned promotional guidance. Consequently some new interventions for the treatment of disease are applied too slowly while others may actually be used prematurely. The consensus development conferences will bring together experts in a specific field for the purpose of
Researchers Seek Sources of Sturm und Drang That Buffet Youngsters During Adolescence
Journal: JAMA (1990)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Primary care and health. A cross-national comparison
Authors: B. Starfield
Journal: JAMA (1991)

Ten Western industrialized nations were compared on the basis of three characteristics: the extent of their primary health service, their levels of 12 health indicators (eg, infant mortality, life expectancy, and age-adjusted death rates), and the satisfaction of their populations in relation to overall costs of the systems. Information was derived primarily from published sources. Indices were developed to characterize the extent of primary care in each country and the standing of each country relative to the others on the health indicators. There was general concordance for primary care, the health indicators, and the satisfaction-expense ratio in nine of the 10 countries. Ratings for the United States were low on all three measures. West Germany also had low ratings. In contrast, Canada, Sweden, and the Netherlands had generally high ratings for all three measures. The lack of concordance in the ratings in the United Kingdom may be a result of relatively low expenditures for other social services and public education in that country. The findings may add to the debate and deliberations concerning modifications in organization and financing of care that are currently being considered in the United States. (<i>JAMA</i>. 1991;266:2268-2271)
Degos' disease
Authors: Julia A. Newton, M.M. Black
Journal: British Journal of Dermatology (1986)

Journal Article Degos' disease Get access Julia A. Newton, Julia A. Newton The Dowling Skin Unit and Institute of Dermatology, United Medical and Dental Schools, Guy's and St Thomas's Hospitals, London SE1 7EH, U.K. Search for other works by this author on: Oxford Academic Google Scholar M.M. Black M.M. Black The Dowling Skin Unit and Institute of Dermatology, United Medical and Dental Schools, Guy's and St Thomas's Hospitals, London SE1 7EH, U.K. Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 115, Issue 2, 1 August 1986, Page 249, https://doi.org/10.1111/j.1365-2133.1986.tb05726.x Published: 01 August 1986
Danazol
Authors: AMOS E. MADANES
Journal: Annals of Internal Medicine (1982)

Danazol, approved 5 years ago for the treatment of pelvic endometriosis, has recently been approved for treating cystic disease of the breast. As the mechanisms of action of this drug are made clear, the clinical syndromes that can be treated by this impeded androgen have increased dramatically. Results of controlled prospective clinical studies on the drug have increased our understanding of the pathophysiology of several poorly understood diseases. Danazol is well tolerated by most patients; the side effects are mild and reversible.
EEG evaluation of lidocaine convulsions
Authors: R. S. Crampton
Journal: JAMA (1968)

<h3>To the Editor:—</h3> With regard to convulsions and respiratory arrest during intravenously administered lidocaine hydrochloride treatment of ventricular tachycardia, I am indebted to Dr. J.T.M. Bamford, of Cooperstown, NY, for drawing attention to an electroencephalographic evaluation of convulsions and respiratory arrest induced by lidocaine<sup>1</sup>omitted from my report (<b>204</b>: 201,1968). In this study, six normal volunteers were given 1.5 to 3 mg/kg/min of lidocaine intravenously for two to six minutes until convulsions appeared. Three exhibited respiratory arrest lasting 260, 310, and 295 seconds, respectively. The convulsions lasted 105 to 125 seconds, and electroencephalographic records revealed epileptic spikes during all seizures. The total convulsant dose ranged from 6 to 9 mg/kg. During the infusion of lidocaine, a transient rise of respiratory rate was followed by decreased excursion of the thorax. Apnea during the convulsion persisted 10 to 15 seconds after the fit with the chest fixed in the expiratory phase
HIV disease in reproductive age women: a problem of the present
Authors: S. H. Landesman
Journal: JAMA (1989)

The era when human immunodeficiency virus (HIV) disease will pose a major threat to women's reproductive health no longer looms in the future. Thousands of pregnancies each year, preponderantly among urban minority women, are already complicated by HIV infection. The contribution of their progeny to infant mortality in the nation's inner cities will soon dwarf that of children with other congenital infections such as cytomegalovirus, herpes, or syphilis. In New York City, 1 in 80 births is to an HIV-infected woman.<sup>1</sup>Even if only 1 in 3 of their children eventually dies of HIV infection, that would result in almost 4.3 deaths in each cohort of 1000 births. There were, by comparison, a total of 9.9 infant deaths per 1000 births in the United States last year.<sup>2</sup>Thus, at a time when HIV is becoming the dominant infection impacting on reproductive health, it is timely that data are
Voice Dictation
Authors: Ryan E. Childers
Journal: Annals of Internal Medicine (2020)

Ad Libitum17 November 2020Voice DictationRyan E. Childers, MDRyan E. Childers, MDThe Oregon Clinic Gastroenterology South, Tualatin, Oregon (R.E.C.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/M19-2225 Audio Reading - “Voice Dictation” Audio. Michael A. LaCombe, MD, Annals Associate Editor, reads “Voice Dictation” by Ryan E. Childers, MD Your browser does not support the audio element. Audio player progress bar Step backward in current audio track Play current audio trackPause current audio track Step forward in current audio track Mute current audio trackUnmute current audio track 00:00/ SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail With our new electronic medical record systems,He quipped with the latestVoice recognition soft. Where,We can queasily dictate patient care notes.Up to one hundred-forty birds a minute!Now weekend speak, rather than typeAnd redo not have to worryAbout encore wrecked punch you Haitan,Or being gray matter Lee correct.Typing words on a key. Bored will fade away.Besides, who past time anymore to type?Important details about our patienceNeed knot be omitted or cleft unsaidDue two time constraints from Taiping.Call leagues and count sultansWill enjoy reading these notes,Which will contain crater information,And a more detailed, express sieve narrative.And surly patients themselves... Author, Article, and Disclosure InformationAffiliations: The Oregon Clinic Gastroenterology South, Tualatin, Oregon (R.E.C.)Current Author Address: Ryan E. Childers, MD; e-mail, [email protected]com. PreviousarticleNextarticle Advertisement Audio Reading - “Voice Dictation” Audio. Michael A. LaCombe, MD, Annals Associate Editor, reads “Voice Dictation” by Ryan E. Childers, MD Your browser does not support the audio element. Audio player progress bar Step backward in current audio track Play current audio trackPause current audio track Step forward in current audio track Mute current audio trackUnmute current audio track 00:00/ FiguresReferencesRelatedDetails Metrics 17 November 2020Volume 173, Issue 10Page: 843KeywordsBeesElectronic medical recordsPatients ePublished: 17 November 2020 Issue Published: 17 November 2020 Copyright & PermissionsCopyright © 2020 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Highlights
Authors: K Chhabra, J Dimick, Cui Bono, D Soybel, K Knuf, K Haisley, M Patti
Journal: JAMA Surgery (2016)

Elwy et al quantitatively assess surgeons' reports of disclosure of adverse events and aspects of their experiences with the disclosure process.Most of the surgeons completing the web-based surveys used 5 of the 8 recommended disclosure items and discussed steps taken to treat any subsequent problems.It was found that surgeons who reported they were less likely to discuss preventability of the adverse event, or who reported diffi cult communication experiences, were more negatively aff ected by disclosure than others.