tbuckley/cabot-search huggingface dataset:
Journal de Chirurgie, Paris
Journal: JAMA (1964)

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Weekend Hospitalization
Authors: Patrick J. Hagan
Journal: JAMA Pediatrics (2014)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Pediatrics HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Pediatrics journal
FRI0322 Correlations of CTX-II with biochemical markers of bone turnover raise questions on its tissue origin: Data from check, a cohort study of early osteoarthritis
Authors: W.E. van Spil, J.W. Bijlsma, S.C. Mastbergen, F.P. Lafeber
Journal: Annals of the Rheumatic Diseases (2013)

<h3>Background</h3> Biochemical markers (biomarkers) are proposed to reflect certain metabolic pathways in health and disease. However, actual molecular validity of biomarkers is often not definite. <h3>Objectives</h3> uCTX-II has been put forward as a marker of collagen type II degradation being part of cartilage degradation in osteoarthritis and is used as (surrogate) end point in therapeutic trials. Here we present data that argue against this assumption and warrant more cautious interpretation of uCTX-II levels. <h3>Methods</h3> uCTX-II, and the bone biomarkers uCTX-I, uNTX-I, sPINP and sOC as well as the cartilage markers sCOMP, sCS846, and sPIIANP were assessed by ELISA in baseline samples of CHECK (Cohort Hip &amp; Cohort Knee), a cohort of 1002 individuals with early complaints of pain and/or stiffness in knee and/or hip. Correlations between biomarkers and between biomarkers and demographics were investigated through multiple linear regression analysis. <h3>Results</h3> uCTX-II was more strongly correlated with bone markers than with the cartilage markers, while the cartilage markers did not show such strong correlations with the bone markers. Moreover, both uCTX-II and bone markers but not the other cartilage markers showed an abrupt menopausal shift in woman at the age of 50-55 years, also when adjusted for age and BMI. <h3>Conclusions</h3> The increased bone marker levels in postmenopausal women are in accordance with the well-known increase in bone turnover after menopause. The many similarities between uCTX-II and bone markers could be attributable to a link between cartilage and bone metabolism through metabolic and biomechanical mechanisms. However, other cartilage markers were hardly correlated with uCTX-II and did not show such evident correlations with bone markers. These data suggest that uCTX-II has unique relations with bone markers as compared to other cartilage markers and reflects bone rather than cartilage metabolism. Accordingly, other authors have suggested osteoclastic resorption of calcified cartilage as the major origin of uCTX-II. More thorough molecular validation of uCTX-II is required to better define its origin. Until then, uCTX-II levels should be interpreted cautiously. This study was funded by CHECK, an initiative of the Dutch Arthritis Association. <h3>Disclosure of Interest</h3> None Declared
Effectiveness of advanced paramedics in a mobile coronary care system
Authors: R. P. Lewis
Journal: JAMA (1979)

The mobilized coronary care system in Columbus, Ohio, began with operation of a single vehicle with a physician in attendance. Currently, advanced emergency medical technician-paramedics work without direct physician supervision. When both experiences are compared, the results indicate that advanced emergency medical technician-paramedics working independently perform as well as physician counterparts. (<i>JAMA</i>241:1902-1904, 1979)
THE PUBLIC HEALTH DEFENSE LEAGUE.
Journal: JAMA (1906)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Pathophysiology And Management Of Hypertension In Diabetes
Authors: M. Tuck
Journal: Annual Review of Medicine (1991)

Arterial hypertension is more common in diabetes mellitus than in nondiabetic subjects, and many metabolic and hemodynamic features of diabetes mellitus contribute to the etiology of hypertension. Control of hypertension in diabetes mellitus is extremely important as high blood pressure accelerates both macrovascular and microvascular complications of this disease. Most classes of antihypertensive agents are effective in blood pressure control in diabetes mellitus, so the choice of antihypertensive therapy is based on the differences in adverse effects of these agents on metabolic control and other cardiovascular risks.
Incorrect Number
Journal: JAMA (1985)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Error in Figure
Authors: Xiao-Ou Shu, Emanuele Crocetti
Journal: JAMA Oncology (2020)

Allen S. Ho, MD; Michael Luu, MPH; Laurel Barrios, BA; Irene Chen, MD; Michelle Melany, MD; Nabilah Ali, PA-C; Chrysanta Patio, PA-C; Yufei Chen, MBBS; Shikha Bose, MD; Xuemo Fan, MD, PhD; Jon Mallen-St. Clair, MD, PhD; Glenn D. Braunstein, MD; Wendy L. Sacks, MD; Zachary S. Zumsteg, MD
Recent Developments in the Multistage Modeling of Cohort Data for Carcinogenic Risk Assessment
Authors: Sati Mazumdar, Carol K. Redmond, Joseph P. Costantino, Rita N. Patwardhan, Susan Y. J. Zhou
Journal: Environmental Health Perspectives (1991)

The n ofcohort data bed on the Arnite-Do multta model ofthecarcinogenic poe has gained popuar acceptance as amethodology for quantitative risk a ent for estimating the dose-related relationships between dif- ferent occupational and environmental carcinogenic exposures and cancer mortality.The multitge model can be used forextapolatin to low doses reln t for settngenvrnntaa l an and abo pa vides in tin rd whether more than one stge is dose-related, which asists In deternining whether diferent arcinogens affect different stages of the cancer process.This paper sm res recent devel p in the multisge modeing ofcobort data and emphasies practical issues such as handling data ariing from large epidemiologic follow-up studies, the time-dependent nature of exposures and staistical issues such as muicoinearity in time-related variables, robustness of parm r estimates, validating ofthe fitted model, and routine inferenti ocedures Problems related to uncertainties ofrisk esimates are discussed aLso, Computer proams for fitting multisge models with one or two dose-related stages to cohort data in- corporating time-dependent exposure patterns; constructing confidence regions for model parameters; and predicting lifetime risks of dying from cancer adjusting for competing causes of death are detailed.Illustrations are provided us- ing lung cancer mortality in a cohort of nonwhite male coke oven workers exposed to coal tar pitch volatiles.
A WATER SYMPOSIUM.
Journal: JAMA (1897)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Electrocardiographic Alterations During Fractional Pneumography
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Noninvasive assessment of coronary artery diameter by transthoracic high resolution doppler technique Nozomi Watanabe, Yasuko Yamaura, Reishi Izumi, Yuji Koyama, Takeshi Sato, Masamichi Oyanagi, Takashi Akasaka, Kiyoshi Yoshida. Kawasaki Medical School, Kurashiki, Japan, Toshiba Corporation, Tokyo, Japan
Journal: Journal of the American College of Cardiology (2001)
Tube trains kill fewer people when there's a pit under the rails
Journal: BMJ (1999)

Behavioural counselling in primary care leads to improvements in health behaviour Behavioural counselling in primary care leads to greater improvements in health behaviour than standard health education and advice in patients at increased risk of coronary heart disease.Previous studies of health promotion and lifestyle counselling in primary care have produced disappointing results.Steptoe et al (p 943) found in a randomised trial that brief behavioural counselling on the basis of the "stage of change" model stimulated greater reductions in dietary fat intake and number of cigarettes smoked, and greater increases in physical activity than did usual care.The results suggest that behavioural counselling in primary care may be a useful strategy in the prevention of coronary heart disease.
INFLUENZA VACCINATION
Journal: JAMA (1961)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Surgery in centenarians
Authors: M. R. Katlic
Journal: JAMA (1985)

Surgical problems do not end on a person's centennial, and as our overall population ages, physicians will see increasing numbers of these most senior citizens requiring surgery. Accordingly, the records of all century-old patients who have undergone surgery at the Massachusetts General Hospital in the years 1979 to 1983 were reviewed. Three men and three women ranged in age from 100 to 104 years at the time of surgery. One patient experienced complications, but all survived their operation and lived one to two years afterward. The centenarian has already been tested by life and found exceptionally fit. Selectivity and meticulous attention to detail remain paramount in treating these patients, but elective surgery should not be deferred, nor emergency surgery denied the centenarian on the basis of chronologic age. (<i>JAMA</i>1985;253:3139-3141)
Heading for Better Health Care in Peru
Authors: M. Mitka
Journal: JAMA (1999)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Beyond our pages
Authors: Burton Zweiman, Marc E. Rothenberg
Journal: Journal of Allergy and Clinical Immunology (2000)

Ataxia-telangiectasia (AT) is a rare, autosomal, recessive disorder characterized by progressive neurodegeneration, conjunctival telangiectasia, and immunodeficiency with hypogammaglobulinemia and decreased levels of circulating CD4+ lymphocytes. There is also a predisposition to recurrent sinopulmonary infections. Although the last feature has been considered secondary to the immunodeficiency, this study of 71 patients with AT showed that oropharyngeal dysphagia is common and often progressive.
FDA committee questions Fluosol efficacy; US approval not imminent
Authors: C. Marwick
Journal: JAMA (1983)

Don't look for perfluorochemical blood substitutes to become available in the United States any time soon. The Food and Drug Administration's Blood Products Advisory Committee has unanimously agreed that the perfluorocarbon oxygen transport fluid Fluosol-DA 20% is not yet ready for release. Recommendations by such committees are forwarded to the Commissioner of the FDA. Fluosol-DA is manufactured by the Green Cross Corporation, Osaka, Japan, which has licensed Alpha Therapeutic Corporation, Los Angeles, to distribute it in the United States. The substance is approved for marketing in Canada, Holland, and Italy. Members of the committee, headed by chair Joseph R. Bove, MD, director of the Blood Transfusion Service at Yale-New Haven Hospital, New Haven, Conn, did not quarrel with the findings of the clinical data presented to them but said they did not think there was sufficient evidence of efficacy—as yet. "Looking over the data [from a multicenter study], the treated
After Bakke, what?
Authors: C. P. Alexis
Journal: JAMA (1978)

AFTER several weeks of great anticipation and expectation, on June 28, 1978, the Supreme Court of the United States handed down its decision in the case of the<i>Regents of the University of California vs Bakke</i>. If I understand this decision, I think it is fair to state that it was twofold. On the one hand, it directed that Bakke be admitted to the Medical School of the University of California at Davis; on the other hand, it stated that race may be considered as one factor in university admissions procedures. The reactions to the Court's decision ran the full gamut of statements and emotions. Some have believed that the Court's decision was a masterpiece of judicial statesmanship, and that while it provided Bakke with victory, it permitted the continuation of what have come to be known as "affirmative action programs." However, there are others who have believed that the
Renal Transplantation
Authors: John F. Mahony
Journal: JAMA (1976)

In 14 of 204 consecutive cadaveric renal allograft recipients, the primary diagnosis was essential hypertension. Four patients had manifest ischemic heart disease before transplantation. Three of these patients died within 31 months of transplantation from recurrent myocardial infarction, and the fourth experienced coronary insufficiency. Cadaveric renal transplantation does not prevent the progression of coronary artery disease in patients whose renal failure was due to essential hypertension. In the presence of angina or previous myocardial infarction, these patients may be better treated by maintenance hemodialysis. (<i>JAMA</i>235:2318-2320, 1976)
Increased expression of intercellular adhesion molecule 1 on bile ducts in primary biliary cirrhosis and primary sclerosing cholangitis
Authors: D Adams
Journal: Hepatology (1991)

It has been suggested that immunological mechanisms involving lymphocyte-mediated damage are important in the characteristic bile-duct damage that occurs in primary biliary cirrhosis and primary sclerosing cholangitis. Because adhesion is necessary for the interaction of lymphocytes with their target structures, we have studied the expression of intercellular adhesion molecule 1, a ligand for the leukocyte adhesion receptor lymphocyte function—associated antigen 1 in the liver of patients with primary biiary cirrhosis and primary sclerosing cholangitis. Strong expression of intercellular adhesion molecule 1 was seen on interlobular bile ducts and proliferating bile ductules in both conditions. In primary biliary cirrhosis, medium-sized ducts, which are spared by the disease, were negative. Minimal bile-duct staining was seen in conditions in which bile-duct damage is not a major feature, such as nonbiliary cirrhosis and acute liver diseases. In patients with cirrhosis from any cause, strong expression of intercellular adhesion molecule 1 was detected on the periseptal hepatocytes adjacent to new connective tissue. The intensity of immunohistochemical staining was recorded using a semiquantitative visual scoring system that was subsequently validated quantitatively by confocal laser scanning microscopy. The expression/induction of intercellular adhesion molecule 1 on bile ducts may be important in the pathogenesis of bile-duct damage in primary biliary cirrhosis and primary sclerosing cholangitis and is further evidence to support an immune pathogenesis in these two conditions. Furthermore, the induction of intercellular adhesion molecule 1 on hepatocytes may be an important factor in the liver-cell damage and fibrosis that occur during the development of cirrhosis.