tbuckley/cabot-search huggingface dataset:
Increased Expression of Activity-Dependent Genes in Cerebellar Glutamatergic Neurons of Patients With Schizophrenia
Authors: Rodrigo Paz
Journal: American Journal of Psychiatry (2006)

Objective: The purpose of this study was to evaluate the functional state of glutamatergic neurons in the cerebellar cortex of patients with schizophrenia. Method: The authors measured messenger ribonucleic acid (mRNA) levels of three activity-dependent genes expressed by glutamatergic neurons in the cerebellar cortex (GAP-43, BDNF, and GABA A -δ subunit) in the tissues of 14 patients with schizophrenia and 14 matched nonpsychiatric comparison subjects. Since its level of expression does not change in response to neuronal activity, gamma-aminobutyric acid A -α6 subunit mRNA was used as a control. Results: The levels of GAP-43 and BDNF mRNAs were significantly elevated in patients with schizophrenia, and a similar finding was observed for GABA A -δ mRNA. In contrast, the levels of the GABA A −α6 subunit mRNA, which is expressed in cerebellar granule cells in an activity-independent manner, did not differ from comparison subjects. Conclusions: These results suggest that glutamatergic neurons may be hyperactive in the cerebellar cortices of patients with schizophrenia.
Impedance cardiography
Authors: B. J. M. van der Meer, H. H. Woltjer, A. M. Sousman, W. O. Schreuder, E. R. Bulder, M. A. J. M. Huybregts, P. M. J. M. de Vries, B. J. M. van der Meer
Journal: Intensive Care Medicine (1996)
Council on Medical Education and Hospitals
Journal: JAMA (1934)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE PHYSICIAN OF THE FUTURE
Journal: JAMA (1926)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
RESEARCH AND TEACHING IN CONNECTION WITH STATE INSTITUTIONS.
Journal: JAMA (1903)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Engage: A Phase 3, Randomized, Double-blind, Placebo-controlled, Multi-center Study To Investigate The Efficacy and Safety Of Eliglustat In Adults With Gaucher Disease Type 1: 9 Month Results
Authors: Suma Shankar, Elena Lukina, Dominick J Amato, Majed Dasouki, Seymour Packman, Gregory M Pastores, Sarit Assouline, Manisha Balwani, Pramod K Mistry, Leorah H Ross, Sachin Marulkar, M. Judith Peterschmitt
Journal: Blood (2013)
Surgical Diseases of the Spinal Cord, Membranes, and Nerve Roots: Symptoms, Diagnosis and Treatment
Journal: JAMA (1941)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Communication and the Journals
Journal: JAMA (2017)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Shared Vision
Authors: Ian Wicks
Journal: JAMA (2017)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Yellow Fever and Cholera.
Journal: JAMA (1883)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Editors' Note on the USPSTF Recommendation on Screening for Breast Cancer
Authors: The Editors
Journal: Annals of Internal Medicine (2010)

Letters20 April 2010Editors' Note on the USPSTF Recommendation on Screening for Breast CancerFREEThe EditorsThe EditorsSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-152-8-201004200-00209 SectionsAboutVisual AbstractPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail In response to media reports that imply otherwise, Annals of Internal Medicine did not schedule the publication of the U.S. Preventive Services Task Force recommendations about breast cancer screening to coincide with a particular date or event. The background papers underwent several rounds of revision over about 5 months, based on comments by independent peer reviewers and an Annals statistical editor. The background papers and the recommendation statement were all in final, accepted form by 10 September 2009. Annals scheduled them for the next available print issue, which was the 17 November 2009 issue. Our routine print production process takes about 2 months from final acceptance to print.—The Editors Comments0 CommentsSign In to Submit A Comment Author, Article, and Disclosure InformationAffiliations: Disclosures: None disclosed. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoWhen Evidence Collides With Anecdote, Politics, and Emotion: Breast Cancer Screening Metrics 20 April 2010Volume 152, Issue 8Page: 544KeywordsBreast cancerBreast cancer screeningCancer screeningConflicts of interest ePublished: 20 April 2010 Issue Published: 20 April 2010 CopyrightCopyright © 2010 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...
The high-affinity receptor for immunoglobulin E. Prospects for the therapy of immediate hypersensitivity reactions
Authors: S. C. Dreskin
Journal: JAMA (1988)

MAST cells and basophils have a plasma membrane receptor that binds immunoglobulin E (IgE) with high affinity.<sup>1</sup>When the bound IgE reacts with antigen, there is an explosive discharge of preformed mediators of inflammation from storage granules, and newly synthesized potent lipids are likewise released. These substances account for many of the symptoms of allergic diseases.<sup>2</sup>Approaches to the therapy of immediate hypersensitivity reactions can be broadly categorized into four principal strategies: (1) suppression of IgE biosynthesis, (2) generation of "blocking" antibodies, (3) prevention of IgE-mediated stimulation of mast cells, and (4) "neutralization" of the effects of the released mediators. We will consider herein the third of these strategies and focus in particular on preventing activation of the cells by interfering with the binding of IgE to the receptor or by aborting the early events that follow triggering of the receptor. It is important to note that a
Occupational Hygiene in the Complex Nitrogen Fertilizers Industry
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Spinal manipulation and mobilisation for back and neck pain.
Authors: S. M. Hay, B. Todd
Journal: BMJ (1992)

<h3>Introduction</h3> There is only limited and conflicting evidence on the effectiveness of Pay-for-Performance (P4P) programmes, although they might have the potential to improve guideline adherence and quality of care. We therefore aim to test a P4P intervention in Swiss primary care practices focusing on quality indicators (QI) achievement in the treatment of patients with diabetes. <h3>Methods and analysis</h3> This is a cluster-randomised, two-armed intervention study with the primary care practice as unit of randomisation. The control group will receive bimonthly feedback reports containing last data of blood pressure and glycated haemoglobin (HbA1c) measurements. The intervention group will additionally be informed about a financial incentive for each percentage point improved in QI achievement. Primary outcomes are differences in process (measurement of HbA1c) and clinical QI (blood pressure control) between the two groups. Furthermore, we investigate the effect on non-incentivised QIs and on sustainability of the financial incentives. Swiss primary care practices participating in the FIRE (Family Medicine ICPC Research using Electronic Medical Record) research network are eligible for participation. The FIRE database consists of anonymised structured medical routine data from Swiss primary care practices. According to power calculations, 70 of the general practitioners contributing to the database will be randomised in either of the groups. <h3>Ethics and dissemination</h3> According to the Local Ethics Committee of the Canton of Zurich, the project does not fall under the scope of the law on human research and therefore no ethical consent is necessary. Results will be published in a peer-reviewed journal. <h3>Trial registration number</h3> ISRCTN13305645; Pre-results.
Corrections
Authors: D.-G Davies, I Rennie, J Rea, B.-J Richardson, D Carr, T Garrett, H Whitfield, J Deknt, M Ahamed, A Beattie, D Bell, R Cranfield, J Dowman, A Munro, H Potter, P Smith, R Wilson, M Baldwin, T Ballantyne, C Bowdidge, J Bradley, N But, S Cooper, P Deasy, R Guest, F Mck, A Hathorn, S Hawker, J Jackson, G Johnson, R Keyes, G Saffhill, J Self, B Stubley, P Vowden, Appointment Aberdeen, J Engeset, Phyllis Fulton, Obstetrics.- M Aboudi, Amal Ai-Azzawi, Souhaila Al-Baghdadi, Samira Al-Daghistany, Haifa Beker, A Halioush, K Hoq, Fawzia Ibrahim, Narmada Kamath, A Khalil, Rehana Khan, Salma Khatoon, Zahida Kwaja, F Mohamed, F Musleh, Khalisa Musrafa, Sarwa Said, M Shah, P Milton, A Boakes, J Curtis, M Noble, J Daly, Marian Edwards, Kathleen Harrison
Journal: BMJ (1969)
Best and Taylor's Physiological Basis of Medical Practice
Authors: Panayotis G. Iatridis
Journal: JAMA (1985)

The 11th edition of<i>Best and Taylor's Physiological Basis of Medical Practice</i>has been edited by Dr John B. West, a well-known respiratory physiologist, and by eight section editors, who are also well known in their areas of expertise. Since its first edition, in 1937, this text in physiology has been widely used by medical and graduate students and by practicing physicians in the United States, Canada, and—having been translated into nine foreign languages—all over the world. The new edition is divided into ten sections: general physiological processes, the cardiovascular system, blood and lymph, body fluids, renal function, respiration, the gastrointestinal system, metabolism, the endocrine system, and neurophysiology; the whole volume contains 72 chapters. Each chapter starts with an introduction and is subdivided into specific topics. At the end of each section is a pertinent bibliography. Taking into account the volume of information available, the whole organization of this textbook
Consultants' communications with general practitioners.
Authors: M. P. Myres
Journal: BMJ (1992)

provincial clinic seeing around 4500 new cases a year.In two weeks 116 calls were made for results and 65 for advice (roughly 9000 annually).Most of these calls were dealt with by clerical and nursing staff, but to do so adequately they require experience and training.If telephone calls are to be used more their use should be included in routine statistics and the demand they make planned for.
RAT DESTRUCTION
Authors: F. N. White
Journal: BMJ (1919)

r Tu-SLICAL JsOUN 6i9 eXercise, and want of surface stimulation-in other words, bad housing conditions-also play important parts, and conduce to tlhat condition of relative overfeeding which I have insisted on as the essential element in leadino to acidosis.Among the well-to do classes overfeeding and under-exercise are the dual causes.
Provision of oxygen at home in Northern Ireland is not cost effective
Journal: BMJ (1999)

Community care of long stay psychiatric patients presents few problems Some attribute the increasing number of homeless people in Britain and the high profile killings by mentally ill people to the closure of psychiatric hospitals and the lack of alternative care.On the basis of a 13 year follow up study, Trieman et al (p 13) show the outcomes for former patients of two psychiatric hospitals and dispel some of the main concerns about their fate in the community.The authors say that a change in policy towards custodial care is unjustified as much as it is unrealistic.
CORRECTION
Journal: CA A Cancer Journal for Clinicians (1967)

According to information provided by him, Gaston Naessens was bom in France between 1922 and 1924.He claims to have studied biol ogy at the University of Lille, but the records fail to verify this.In 1956 he was convicted of illegally practicing medicine.He was fined 300,000 old francs and made to pay 600,000 old francs to the doctors' â€oe¿ ordreâ€• and â€oe¿ syndicat.â€•From that time on, he has made it conditional that a doctor should administer his treatment.
Autologous blood donations prior to elective cardiac surgery. Safety and effect on subsequent blood use
Authors: D. V. Owings
Journal: JAMA (1989)

Blood transfusions are frequently necessary for patients having open heart surgery. Although autologous blood is free of such risks as transfusion-transmitted diseases, the safety and effectiveness of autologous donations by cardiac patients are debated. We analyzed the records of 291 consecutive patients undergoing elective open heart surgery. One hundred seven (36.8%) donated between 1 and 6 U of autologous blood (mean, 3.0 ± 1.5 U) before undergoing surgery. First-time elective coronary artery bypass surgery was the most common indication for autologous donation (90.6% of autologous donors). Problems following donations were infrequent (2 of 326 donations) and without long-term consequences. Among patients having coronary artery bypass surgery who donated autologous blood, 27% required homologous blood transfusions as compared with 82% of other patients undergoing the same procedure. We conclude that autologous blood donations are safe for patients with cardiac disease and effective in significantly reducing homologous blood needs in patients undergoing elective coronary artery bypass surgery. (<i>JAMA</i>. 1989;262:1963-1968)
MEDICAL EDUCATION FOUNDATION ENTERS SECOND YEAR
Journal: JAMA (1952)

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