tbuckley/cabot-search huggingface dataset:
Holmes Heart—Variant of Cor Triloculare Biatriatum: Report of Case in a Child
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hairy legs.
Journal: BMJ (1976)

work.This result may well have delayed the introduction of flooding.Nevertheless, undoubtedly behaviourism has pro- vided a framework for the development of behaviour therapy, which has been a framework for the application of common sense.The link may be tenuous-a controversial theory of psychosexual development provided a framework for the development of individual psychotherapy-but the need for these frameworks must surely tell us something about human psychology.
Functional inactivation of neutrophils with a Mac-1 (CD11b/CD18) monoclonal antibody protects against ischemia-reperfusion injury in rat liver
Authors: H Jaeschke
Journal: Hepatology (1993)

The role of neutrophil CD11b/CD18 (Mac-1) adhesion proteins in the pathogenesis of hepatic reperfusion injury was investigated in an experimental model. Male Fischer rats were treated with a CD11b monoclonal antibody or an isotype-matched IgM control antibody and subjected to 45 min of hepatic ischemia followed by 24 hr of reperfusion. Large numbers of neutrophils were present in postischemic liver lobes (1,241 ± 64 polymorphonuclear cells/50 high-power fields) compared with numbers in baseline measurements (14 ± 3 polymorphonuclear cells/50 high-power fields), and severe liver injury was observed after 24 hr of reperfusion (hepatic necrosis: 88% ± 2%). Pretreatment with the CD11b antibody (two doses of 2 mg/kg each) significantly attenuated liver injury and reduced the number of polymorphonuclear cells in the postischemic liver by 59%. Selective treatment with the antibody only during reperfusion was similarly effective. The increased spontaneous superoxide formation of neutrophils isolated from postischemic liver (1.05 ± 0.11 nmol O2−/hr/106 cells) was reduced by 56% in neutrophils from CD11b antibody-treated animals. Flow cytometric analysis of CD11b/CD18 expression on circulating neutrophils demonstrated significant upregulation at all time points during reperfusion. Clone 17 also effectively inhibited neutrophil extravasation in a glycogen peritonitis model. Our data are consistent with a dual protective effect of the CD11b antibody in hepatic reperfusion injury in vivo (i.e., reduced accumulation of neutrophils and their functional inactivation). (HEPATOLOGY 1993;17:915–923.)
Congestive Heart Failure
Authors: Bernhard A. Kats
Journal: JAMA (1992)

This is the 17th in a series of interactive patient management programs that analyze problems common in the primary care setting. The programs have been published by Cardinal Health Systems Inc since 1982 and include such topics as type II diabetes, coronary artery disease, acute respiratory failure, and hypertension. "the essentials in 612 kilobytes and 67 pages" The program<i>Congestive Heart Failure</i>is for teaching medical students and residents and provides practicing physicians with an opportunity to review their skills. It consists of three modules of tutorials, tools, and five case studies. The printed text presents information on the approach to evaluation and treatment. We all remember the complicated schemes with which our teachers tried to make us understand the intricacies of the pathophysiology of congestive heart failure (CHF), a condition that appears to affect all organ systems at some time in its natural history. It has been difficult to
Silicone gel breast implants. Council on Scientific Affairs, American Medical Association
Authors: Yank D. Coble, E. Harvey Estes, C. Alvin Head, Mitchell S. Karlan, William R. Kennedy, Patricia Joy Numann, William C. Scott, W. Douglas Skelton, Richard M. Steinhilber, Jack P. Strong, Katherine A. Schneider, Henry N. Wagner, Jerod M. Loeb, Robert C. Rinaldi, Donald R. Bennett
Journal: JAMA (1993)

In 1991, the American Medical Association's Council on Scientific Affairs prepared a report (Report M) on the silicone gel breast implant controversy and the U.S. Food and Drug Administration regulatory history of breast implant devices through August 1991. The recommendations of Report M were adopted as amended by the AMA's House of Delegates at its 1991 Interim Meeting. This follow-up report (Report C) by the Council on Scientific Affairs covers the continuing FDA regulatory history through October 1992 and was adopted as amended at the 1992 Interim Meeting of the AMA's House of Delegates.
Clinical management of total artificial heart drive systems
Authors: J. B. Mays
Journal: JAMA (1988)

THE EVOLUTION of the total artificial heart (TAH) from animal experimentation to clinical research has necessitated major changes in the control of the drive equipment responsible for prosthesis function. Our experience with patients who have been permanent recipients of the heart has contributed to a refinement of the operating protocol and furthered understanding of the hemodynamic response to artificial circulation devices. <h3>PROSTHESIS DESIGN</h3> The basic design of the pneumatic TAH has changed little since early animal experimentation and still incorporates a flexible diaphragm inside a semirigid housing.<sup>1-3</sup>In the Jarvik-7-100 (Symbion, Inc, Salt Lake City) ventricles, which constitute the device under discussion herein, polyurethane polymer (Biomer, Ethicon Inc, Somerville, NJ) is molded with Dacron polyester mesh to form the semirigid housing. Four layers of Biomer each 0.18 mm in thickness constitute the inflatable diaphragm. Graphite powder between the diaphragm layers deters creation of a flexion crease, which could lead
Transfemoral pacing with balloon-tipped catheters
Authors: S. G. Meister
Journal: JAMA (1973)

A method for rapid, bedside institution of temporary pacing has been developed utilizing floating, balloon-tipped, bipolar pacing catheters inserted percutaneously via a femoral vein. Successful pacing was accomplished without fluoroscopy in 30 of 31 patients. Ease and rapidity of insertion have been remarkable. The preformed "J" configuration of the catheter plus the transfemoral route of insertion aid in the attainment of a stable pacing position at the apex of the right ventricle.
What component of prenatal care is responsible for improved outcome?
Authors: R. C. Wallach
Journal: JAMA (1995)

<h3>In Reply.</h3> —Dr Rosner and Drs Clancy and Brody<sup>1</sup>observe that the Council on Ethical and Judicial Affairs failed "to come to terms" in its report with "the inherent tension between caring for individual patients and populations of patients and the physician's role in resource allocation."<sup>1</sup>Clancy and Brody further state that the Council "fails to articulate a basic truth" that when physicians use resources for their patients, they are depriving other patients of those resources.<sup>1</sup> The Council's report directly acknowledged and responded to these concerns. First, the Council observed that, "[w]hen deciding whether to order a test or procedure for a patient," physicians in managed care are expected to "consider whether the slot should be saved for another patient or not used at all to conserve the plan's resources." However, as Rosner points out, this expectation can seriously undermine the physician's traditional role as patient advocate.
Abuse of amitriptyline
Authors: M. J. Cohen
Journal: JAMA (1978)

Amitriptyline hydrochloride (Elavil) is frequently used in treating mild to moderate depressive states. A survey of 346 persons enrolled in a methadone maintenance program showed that 86 (25%) had admitted taking amitriptyline with the purpose of achieving euphoria. Thin-layer chromatography of random urine specimens over five months showed that 34% of the patients had a positive result for amitriptyline at least once during this time. These results suggest that misuse of amitriptyline is not uncommon and should be carefully considered prior to prescribing this agent to narcoticdependent persons. (<i>JAMA</i>240:1372-1373, 1978)
THE WAR NEWS OF THE WEEK.
Journal: JAMA (1898)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Prognostic Disclosure
Authors: James R. Webster
Journal: Annals of Internal Medicine (2002)

Letters3 September 2002Prognostic DisclosureJames R. Webster Jr., MDJames R. Webster Jr., MDBuehler Center on Aging; Chicago, IL 60611Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-137-5_Part_1-200209030-00018 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:The study by Lamont and Christakis (1) on how physicians give prognoses to preterminal patients with cancer confirms what many have observed anecdotally for some time. I would suggest yet another possible reason for the lack of “explicit, frank verbal communication about prognosis to dying patients.” Physicians too often consider the death of a patient a virtual defeat. We are by psychology, education, training, and societal expectations encouraged to believe that we can rescue all patients and fix anything. Until we accept that there is a death rate of one per person; that comfort, mental, spiritual, and ...References1. Lamont EB, Christakis NA. Prognostic disclosure to patients with cancer near the end of life. Ann Intern Med. 2001;134:1096-105. [PMID: 11412049] LinkGoogle Scholar2. Goodwin JS. Geriatrics and the limits of modern medicine. N Engl J Med. 1999;340:1283-5. [PMID: 10210715] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: James R. WebsterJr., MDAffiliations: Buehler Center on Aging; Chicago, IL 60611 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoPrognostic Disclosure to Patients with Cancer near the End of Life Elizabeth B. Lamont and Nicholas A. Christakis Prognostic Disclosure David Grossman Prognostic Disclosure Michael GuntherMaher Prognostic Disclosure Elizabeth B. Lamont and Nicholas A. Christakis Metrics 3 September 2002Volume 137, Issue 5_Part_1Page: 368KeywordsBehaviorDeath ratesDisclosureForecastingMotivationPsychology ePublished: 3 September 2002 Issue Published: 3 September 2002 Copyright & PermissionsCopyright © 2002 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
ASSOCIATION NEWS.
Authors: Augustus P. Clarke
Journal: JAMA (1897)

<h3>Section on Physiology and Dietetics.</h3> —It is the earnest desire on the part of the managing officers of this Section that its work at the coming meeting in Philadelphia shall be attended with success. The field in which subjects for contributions may be chosen will, on a little reflection, be seen to be large and varied. It is therefore hoped that the members of theAmerican Medical Associationwho are expecting to attend this semicentennial meeting will be free to make contributions to this Section, and that they will send at an early date the titles of their papers to my address or to that of Dr. E. Cutter, the Secretary, Equitable Building, New York City.
Book Review Technique in Trauma: Planned timing in the treatment of wounds including burns. From the Montreal General Hospital and McGill University. By Fraser B. Gurd, M.D., CM.; and F. Douglas Ackman, M.D., C.M. In collaboration with John W. Gerrie, M.D., CM., Edward S. Mills, M.D., CM., Joseph E. Pritchard, M.D., and Frederick Smith, M.D. Preface by John S. Lockwood, M.D. With commentary by Ralph R. Fitzgerald, M.D., CM. 4°, cloth, 68 pp., with 3 plates, 17 figures, 5 tables and 3 charts. …
Journal: New England Journal of Medicine (1945)
Late pancreatic toxicity in patients with breast cancer after taxane-anthracycline–based neoadjuvant and adjuvant chemotherapy.
Authors: M. V. Kopp, I. Koroleva, A. N. Kasulin, J. A. Kucheryavyy, M. J. Byakhov
Journal: Journal of Clinical Oncology (2010)

e11043 Background: Gastrointestinal toxicity in patients treated with chemotherapy is usually considered as early toxicity in short time after chemotherapy. Some gastrointestinal abnormalities are found during long follow-up after the end of chemotherapy. We conducted a retrospective analisis of toxicity of breast cancer patients during neoadjuvant and adjuvant chemotherapy and after chemotherapy. Methods: We retrospectively have analyzed toxicity in 1,643 patients treated for HER2-negative breast cancer between 1993 and 2003. All patients received taxane-anthracycline–based chemotherapy regimens (paclitaxel 175 mg/m2 and doxorubicin 50 mg/m2 or docetaxel 75 mg/m2 and doxorubicin 50 mg/m2), at 21 days intervals, for 4 cycles as neoadjuvant and 4 cycles as adjuvant. All patients underwent mastectomies between fourth and fifth cycles of chemotherapy. Interval between fourth and fifth cycles was not longer then 8 weeks. Results: The mean age was 51.6 years (28–70 years). The follow-up mean was 2.9 years (1-5 years) after the end of chemotherapy. All patients had normal metabolic tests before chemotherapy. Acute pancreatoxicity was found in 9.1% patients during 1-8 cycles of chemotherapy. 5.2% patients had abdomen pain, metabolic abnormalities and ultrasound signs of acute pancreatitis. Only metabolic abnormalities and ultrasound signs (subclinical form) were found in 3.9% patients. During follow-up late pancreatoxicity (chronic pancreatitis) was diagnosed in 20.6% patients. 50% patients with chronic pancreatitis manifested during follow-up period had had pancreatoxicity during neoadjuvant and adjuvant chemotherapy. Conclusions: These results show the need to control metabolic tests, to perform ultrasound scanning of abdomen and to adapt treatment according to the pancreatic function during chemotherapy and for a long time after chemotherapy. No significant financial relationships to disclose.
The patient with a permanently implanted pacemaker
Authors: W. H. Barry
Journal: JAMA (1976)

THE USE of permanent cardiac pacemakers for control of symptomatic bradyarrhythmias has become widespread, and the practicing physician is likely to encounter a patient who is being treated with one of these devices. We will review briefly some aspects of pacemaker function and methods of follow-up that we have found to be of interest to physicians as well as patients, based on our experience in operating the Stanford Pacemaker Clinic, where more than 100 patients with permanent pacemakers have been followed up for the past 5 years. <h3>Technical Considerations</h3> Each pacemaking system consists basically of two components: the pacemaker impulse generator and the pacemaker electrode. The most common power source for permanent impulse generators has been the zinc-mercuric oxide battery cells that provide a relatively constant output of electrical energy for 90% of their life and then decay rapidly to zero output. Pacemakers usually have four or five of these
The cardiopulmonary failure of sleep-disordered breathing
Authors: J. B. Hall
Journal: JAMA (1986)

SLIGHTLY more than 100 years following the publication of the<i>Pick-wick Papers</i>, wherein Charles Dickens described the hypersomnolent and obese character Joe, the term<i>pickwickian syndrome</i>was applied to a group of patients exhibiting obesity, hypersomnolence, hypoventilation, and erythrocytosis.<sup>1</sup>Since this descriptive report, a large amount of information regarding the clinical spectrum, pathophysiology, and treatment of various forms of sleep-induced breathing disorders has been generated,<sup>2</sup>requiring increased clinical awareness of methods of diagnosis and treatment. Sleep-induced breathing disorders include the following: sleep apnea syndromes, such as central, obstructive, and mixed apnea; primary alveolar hypoventilation; periodic or irregular breathing patterns; and nocturnal hypoxemia in chronic obstructive pulmonary disease (COPD) or neuromuscular disorders (NMD). Apneas are defined as the complete cessation of ventilation and may be analyzed by<i>polysomnography</i><sup>3</sup>—the simultaneous recording during sleep of an electroencephalogram (to characterize sleep stage and pattern), measures of airflow (by means of
THE RIGHT TO GIVE AND TO TAKE DISEASE.
Journal: JAMA (1904)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Special Contribution
Journal: JAMA (1962)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Gallstones
Authors: K. S. Gurusamy, B. R. Davidson
Journal: BMJ (2014)

The aim of this study was to compare the effectiveness of subcutaneous and intravenous fluid therapy in hydrating, elderly acute stroke patients. Thirty-four such patients, needing parenteral fluids because of impaired consciousness or dysphagia, were randomly allocated to receive either subcutaneous or intravenous fluids (2 litres of dextrose-saline/24 hours). Serum osmolality was measured before starting fluid therapy (Day 1) and on Days 2 and 3. An analysis of covariance of the osmolalities showed no statistical difference between the two groups (P = 0.12). The total cost of cannulae used over the 3 days for the subcutaneous route was approximately a third of that for the intravenous route. Complication rates were similar for the two groups. The results suggest that subcutaneous fluid therapy is an effective alternative to the intravenous route.
Geriatric Medicine
Authors: Isaac Kleinman
Journal: Annals of Internal Medicine (1998)

Medical Writings15 April 1998Geriatric MedicineIsaac Kleinman, MDIsaac Kleinman, MDBaylor College of Medicine, Houston, TexasSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-128-8-199804150-00036 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail 3rd edition. Cassel CK, Cohen HJ, Larson EB, Meier DE, Resnick NM, Rubenstein LZ; eds. 1070 pages. New York: Springer-Verlag; 1997. $130.00. ISBN 0387946926. Order phone 800-777-4643.Field of medicine: Geriatrics.Format: Hardcover book.Audience: Practitioners and students of geriatrics.Purpose: To assemble and codify the body of geriatric knowledge in a way that is useful for both practicing clinicians and physicians in training.Content: In this new edition, the material has been completely reorganized. In-depth chapters on theories of aging, death, and demographic trends have been included, as have good chapters on rehabilitation, management of patients in long-term care ... Author, Article, and Disclosure InformationAffiliations: Baylor College of Medicine, Houston, Texas PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 15 April 1998Volume 128, Issue 8Page: 699-700KeywordsAgingElderlyGeriatricsHypothermiaIncontinenceLong-term careNeurodegenerative diseasesParalysisPatientsPublic policy ePublished: 15 August 2000 Issue Published: 15 April 1998 Copyright & PermissionsCopyright © 1998 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...