tbuckley/cabot-search huggingface dataset:
Basic Mechanisms of Ovarian Function: Germ Cells
Authors: Stephen E. Harris
Journal: Environmental Health Perspectives (1978)

Recent work is reviewed on several molecular aspects of gene expression during oocyte maturation and early development. Several analyses have been carried out on protein synthesis patterns using the high resolution two-dimensional polyacrylamide gel electrophoresis technique. The protein pattern of some 400–500 spots in sea urchin oocytes before and just after fertilization are quite similar. By gastrula, major stage specific protein changes have been noted. In a similar study major protein changes are noted during the meiotic maturation process in mammals. With the use of the single-copy DNA hybridization technique, the quantitative levels of rare mRNA sequence expression have been determined during oogenesis and early development in the sea urchin model. The mature oocyte sequence set of some 37 × 106 nucleotides of information (or potentially 18,500 different proteins) is synthesized during oogenesis and slowly utilized during development. The sea urchin gastrula mRNA is predominantly synthesized by the embryo genome; however, essentially all those gastrula mRNA sequences can also be found in the mature oocyte (maternal) set. It is proposed by Hough-Evans et al. that this maternal sequence set, which is made during oogenesis and both utilized (translated in 10,000–20,000 proteins), and in part, continually synthesized by all stages of the embryo, plays a critical role in the morphogenic formation of a sea urchin embryo.
The God of Small Things
Authors: Eric M. Chang
Journal: JAMA (2020)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Defibrillation-Reply
Authors: Henry S. Loeb
Journal: JAMA (1976)

<h3>In Reply.—</h3> Prompt defibrillation is essential, and undue delay must be avoided if satisfactory results are to be expected. At present, it seems that for average-size adults, a dose of 400 wattseconds is safe and likely to result in a successful defibrillation on the first attempt. As indicated, large adults may require more than 400 watt-seconds, a requirement that is above the capacity of most defibrillators currently in use. I would think that in the future, defibrillators might be equipped with buttons to be pressed when the subject is very large or when more than 400 watt-seconds is desired. This would avoid accidental delivery of excessive current to normal-size individuals, but would permit delivery of greater than usual (ie, 600 to 700 watt-second) currents when needed, without the loss of time required to calculate individual doses based on patient body weight.
Cardiopulmonary Schistosomiasis.
Authors: H. F. Rodriguez
Journal: Annals of Internal Medicine (1961)

s1 May 1961Cardiopulmonary Schistosomiasis.H. F. Rodriguez, M.D., (Assoc.), A. F. Duran, M.D., L. G. Moliner, M.D.H. F. Rodriguez, M.D., (Assoc.)Search for more papers by this author, A. F. Duran, M.D.Search for more papers by this author, L. G. Moliner, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-54-5-1057_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe most severe clinical manifestation of bilharziasis occurs when prolonged and extensive obstruction of the pulmonary arterioles by ova leads to pulmonary hypertension and cor pulmonale.An analysis of 1,100 consecutive autopsies performed in four and one-half years disclosed 54 patients withSchistosomiasis mansoniof the liver and portal hypertension. Of these, 18 (33%) had pulmonary vascular obstruction of such degree as to produce bilharzial cor pulmonale. The clinical characteristics and results of radiographic and cardiac catheterization studies of these 18 subjects, as well as of seven additional living patients, will be discussed. The differentiating features from other conditions leading... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySpontaneous Rupture of Thoracic Aorta Through an Atheromatous Plaque: Case Report and Literature ReviewPenetrating aortic ulcer: Clinical and angiographic characteristicsSpontaneous rupture of the descending aorta through atherosclerotic plaque: Report of a caseAortic rupture in manual dissection of the esophagus: A rare complication during palliative esophagectomy performed on account of radiated esophageal cancer. A pathologic-anatomic viewCase 44-1977Cor pulmonale due to Schistosoma mansoniThe Protean Manifestations of Schistosomiasis Mansoni A Clinicopathological CorrelationMARIO R. GARCÍA-PALMIERI, M.D., F.A.C.P., RAÚL A. MARCIAL-ROJAS, M.D. 1 May 1961Volume 54, Issue 5Page: 1057-1057KeywordsArteriolesAutopsyCatheterizationLiverPortal hypertensionPulmonary hypertensionSchistosomiasis Issue Published: 1 May 1961 PDF downloadLoading ...
Hysterectomy Prevalence, Cervical Cancer Deaths
Journal: JAMA (1992)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Surgery in Italy
Journal: JAMA (1971)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Statistical data on medical schools in the United States
Journal: JAMA (1975)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
(13) Tolerance of spironolactone
Authors: B.R. Hughes, W.J. Cunliffe
Journal: British Journal of Dermatology (1987)

In recent years, the anti-androgenic properties of spironolactone have been used in the treatment of acne and hirsutism. Consequently, the drug has been used for a younger population of patients and also at a higher dose. Forty-four patients (43 female and 1 male), mean age 37 years (range 28–50 years), who had been treated with spironolactone, were reviewed to determine their tolerance of the drug. Treatment was commenced at 200 mg daily. The average duration of treatment was 14 months (range 1–45 months). The most common side-effect was disturbance of menstruation (66%). Ten patients had irregular periods; 11, intermenstrual bleeding; 10, ammenorrhoea; eight, lighter blood loss during periods; two, heavier periods; and seven, more frequent periods. Twenty-seven per cent complained of breast enlargement and 30% of breast tenderness; 18% complained of nausea; 39% admitted to having dry skin. Four patients experienced this symptom severely enough to produce itching and scaling. Two patients complained of abnormal facial pigmentation resembling chloasma—a previously unreported side-effect of spironolactone. Other less common side-effects were vomiting, dizziness, drowsiness, headaches, abdominal pain, loss of short-term memory and malaise. Side-effects tended to occur early and persist throughout treatment and were managed in some cases by alteration of the dose of the drug. Only four patients withdrew from treatment. The patients tolerated the side-effects well, despite the high incidence, in view of the drug's beneficial effects.
Contents
Authors: Chinmoy Bhate, Robert Schwartz, Christian Kunte, Jens Baumert, Birger Konz, Matthias Volkenandt, Michael Flaig, Thomas Ruzicka, Carola Berking, Monika-H Schmid-Wendtner, Hong Liang Tey, Andy Leong Tan, Bruce Strober, Yves Poulin, Francisco Kerdel, Richard Langley, Yihua Gu, Shiraz Gupta, Martin Okun, Kim Papp, Katherine Evans, Andrea Troxel, Barbara Denardo, Camille Introcaso, Alain Rook, Ellen Kim, Hobart Walling
Journal: Journal of the American Academy of Dermatology (2011)
Les maladies des veines et leur traitement.
Journal: JAMA (1933)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Prognosis of melanoma
Authors: D. N. Silvers
Journal: JAMA (1983)

<h3>To the Editor.—</h3> In their article entitled "Malignant Melanoma in Black American and White American Populations" (1982;248:1856), Dr Reintgen and associates present data that purport to demonstrate "the aggressive nature of this disease in the American black." In their study, 60% (20) of the 31 cases of melanoma in blacks occurred on the sole of the foot or subungually, while less than 3% (75) of the more than 2,500 white patients had volar or subungually situated melanoma. Although the authors state that they controlled variables such as the site of the primary lesion and the level of tumor invasion, I had a difficult time identifying specific data in the article that compared the black volar and subungual lesions with the subset of lesions occurring at these same anatomic sites in the white patients. My experience with volar and subungual melanomas in both blacks and whites is that they are typically
NETHERLANDS
Journal: JAMA (1925)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Incorrect Data in Abstract
Authors: John Blosnich, Melissa Dichter, Catherine Cerulli, Sonja Batten
Journal: JAMA Psychiatry (2015)

Yoji Hirano, MD, PhD; Naoya Oribe, MD, PhD; Shigenobu Kanba, MD, PhD; Toshiaki Onitsuka, MD, PhD; Paul G. Nestor, PhD; Kevin M. Spencer, PhD
New Names
Journal: JAMA (1968)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Etiology and Diagnosis in the Treatment of Infertility in Men
Journal: JAMA (1952)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Psychoactive Drug Use and AIDS
Authors: Giovanni Rezza
Journal: JAMA (1990)

<h3>To the Editor.—</h3> Kaslow et al<sup>1</sup>found that psychoactive substance use did not accelerate the progression toward acquired immunodeficiency syndrome (AIDS) in a large cohort of homosexual men. However, as reported by the authors, the numbers of intravenous drug and opiate users were small. In previous studies, frequent drug injection was found to be associated with T4-cell loss.<sup>2</sup>However, the relationship between continued drug injection and incidence of AIDS in infected subjects remains unclear. We are conducting a cohort study to estimate the risk of developing AIDS in human immunodeficiency virus seroconverters who are intravenous drug users (IVDUs).<sup>3</sup>Most of them admitted to continued drug injection, mainly heroin injection, after human immunodeficiency virus seroconversion. To study the role played by drug injection in the progression of human immunodeficiency virus infection, we compared the incidence of AIDS in 261 seropositive IVDUs to that in 89 non—drug-injecting homosexual men.
Erratum
Journal: JNCI Journal of the National Cancer Institute (1972)

In Guest Editorial “Asbestos Cancers” by J. G. Wagner (May 1971, vol. 46, No. 5). The last sentence on page VII, carrying over to page VIII, should have read, “The small human risk of developing mesothelioma of the pleura from chrysotile may well be due to its curly nature which prevents [not permits] most of it from reaching the pleura,”
ASSOCIATION NEWS.
Authors: H. P. Newman
Journal: JAMA (1896)

<h3>Notice.</h3> —Members contemplating attending the Atlanta meeting will please bring their receipts for dues of 1896 and thereby save second payment. Very truly yours, Chicago, April 23, 1896. <h3>Notice to the Ophthalmological Section.</h3> —The Section dinner will be held at the Aragon Hotel, Atlanta, Tuesday evening, May 5, at 8:30 P.M. The charge will be $2 a plate, and it is hoped that ladies will attend. The dinner is in the hands of Dr. Dunbar Roy, "The Grand," Atlanta, Ga. All desiring to attend will please communicate with him at once, that he may have some idea as to the number for which to provide. It is hoped that the attendance will be large. Frank Allport, M.D., Secretary. Minneapolis, April 21, 1896. <h3>Section on Diseases of Children.</h3> A. C.Cotton, Chairman, Chicago, Ill. A. J.Work, Secretary, Elkhart, Ind. Executive Committee—C. G.Jennings, Detroit, Mich.; W. S.
Declining transplantability of prospective kidney transplant recipients
Authors: J. S. Cheigh
Journal: JAMA (1981)

The total number of cadaveric kidney transplants has been declining, despite an increasing dialysis population, greater understanding of transplant immunology, and improved transplant management. To explore the causes of this decline, various factors were studied in 140 dialysis patients who were awaiting transplantation and 100 consecutive recipients of cadaveric kidney transplants. The study indicates that there is a growing, now predominant, prospective kidney recipient population that is highly sensitized because of previous blood transfusions and kidney transplantations. As a result, 92% of the prospective recipients exhibit varying degrees of lymphocytotoxic antibodies. Thus, a major problem in clinical transplantation is the growing number of dialysis patients who are virtually untransplantable. The declining number of cadaveric kidney transplantations may be caused by, in part, changing immunologic characteristics in the recipient population. (<i>JAMA</i>1981;246:135-139)
LETTER FROM LONDON.
Authors: None G. O. M.
Journal: JAMA (1889)

(FROM OUR OWN CORRESPONDENT.) Tetanus as an Infectious Disease—The Scottish System of Admitting Voluntary Patients into Lunatic Asylums—The Microscopic Examination of Urinary Deposits—The Antiseptic Power of Hydronaphthol—Miscellaneous Notes. Tetanus as an infectious disease is now attracting a great deal of attention. At a recent medical meeting a member dwelt upon the virulence of the soil when contaminated by the dejections of tetanic horses. He insisted upon the frequency of tetanus in wounds of the lower extremities. Thus, in Havana, it was stated, out of 162 patients suffering from tetanus 132 had contracted it from wounds of the legs and feet. The disease is frequent in persons who after being wounded get in contact with the soil, as in the cases of comminuted fracture, in which the bones are forced into the ground, and crushing of the bare feet, also when the injury is inflicted with an agricultural instrument. Experiments made