tbuckley/cabot-search huggingface dataset:
The Histone Methyltransferase Inhibitor, DZNep, Upregulates TXNIP, Increases ROS Production and Targets Leukemia Cells In AML
Authors: Jianbiao Zhou, Chonglei Bi, Shaw-Cheng Liu, Kian-Ghee Tay, Lip-Lee Cheong, Tze-Loong Koh, Qiang Yu, Wee-Joo Chng
Journal: Blood (2010)
Massachusetts Medical Society
Authors: John Figgis Jewett
Journal: New England Journal of Medicine (1956)

COMMITTEE ON MATERNAL WELFAREEclampsia and Subarachnoid HemorrhageA thirty-six-year-old gravida VII, para IV, died with eclamptic convulsions and a subarachnoid hemorrhage two weeks before her estimated date of confinement.The history included 4 term deliveries after two-hour labors that produced babies weighing 3.8 to 4.5 kg. (8 1/2 to 10 pounds). It is categorically stated that there had been no toxemia in any of these pregnancies and no complications. They were her first 4 pregnancies. After 2 miscarriages, a four-year interval preceded the current pregnancy, for which she was examined at two and a half months with a normal . . .
Government Services
Journal: JAMA (1931)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Suramin awakes?
Authors: H M Pinedo, R E van Rijswijk
Journal: Journal of Clinical Oncology (1992)

Article Tools Article Tools OPTIONS & TOOLS Export Citation Track Citation Add To Favorites Rights & Permissions COMPANION ARTICLES No companion articles ARTICLE CITATION DOI: 10.1200/JCO.1992.10.6.875 Journal of Clinical Oncology - published online before print September 21, 2016 PMID: 1588368 Suramin awakes? H M PinedoxH M PinedoSearch for articles by this author , R E van RijswijkxR E van RijswijkSearch for articles by this author https://doi.org/10.1200/JCO.1992.10.6.875 First Page PDF © 1992 by American Society of Clinical Oncology
Task Force 6: Code of Conduct for Staff and Volunteer Leadership
Authors: Pamela S. Douglas, Thomas J. Ryan, George A. Beller, Edward F. Hines, David Wm. Livingston, Christine W. McEntee, Nancy A. Brown, Karen J. Collishaw, Arthur Garson, Rose Marie Robertson, Sidney C. Smith, Gayle R. Whitman
Journal: Circulation (2004)
The anatomy of a clinical information system
Journal: BMJ (1998)

Reforming the Russian health serviceHealth service reform is an important part of the growth of democracy in Russia, and several Western groups have been helping the Russians tackle this huge task.Since 1992, general practitioners in the United Kingdom and medical teachers at the Medical Academy of Postgraduate Studies in St Petersburg have been sharing knowledge on medical education and primary health care.In this article, Dr Peter Toon, the UK coordinator, and Russian doctors involved in the partnership describe Russian health care and attempts at its reform from different perspectives.Russian health care is burdened by its massive inhuman scale and a heavy authoritarian bureaucracy
A novel mutation of the protein C gene with a frameshift deletion of 3 base pair F (3380AGG) in exon 6 in type 1 deficiency associated with arterial and venous thrombosis
Authors: Toru Takahashi, Kenji Shinohara, Ryohei Nawata, Machiko Wakiyama, Naotaka Hamasaki
Journal: American Journal of Hematology (1999)
Acute myocardiopathy following tripathway exposure to methylenedianiline
Authors: L. J. Brooks
Journal: JAMA (1979)

METHYLENEDIANILINE (MDA), or 4,4′-diaminodiphenylmethane, has been used for more than 30 years in the plastics and rubber industry as an epoxy resin hardener. Its acute hepatotoxic properties following absorption via the oral and percutaneous routes have been well established.<sup>1-3</sup>Acute myocardial involvement in addition to the expected hepatitis following intense MDA exposure has not been previously appreciated. <h3>Report of a Case</h3> A 20-year-old man was admitted to Buffalo (NY) Children's Hospital for chest and abdominal pain of five days' duration. He had been employed for two weeks at a chemical plant, where he handled large quantities of MDA. Six days prior to admission, a malfunction in the air filtering system had resulted in the spewing of MDA, in the form of a yellow dust, into the air. While the filter was being repaired, the patient had taken down the top of his protective full-sleeve coveralls and lunched, sweating in
A syndrome resembling pheochromocytoma following a stroke. Report of a case
Authors: R. M. Mazey
Journal: JAMA (1974)

A 38-year-old hypertensive patient suffered a stroke. Pheochromocytoma was suspected because of the clinical history, an extremely labile blood pressure that responded to therapy with a-adrenergic blocking agents, and elevated vanillylmandelic acid (VMA) and catecholamine excretion rates. However, on the basis of a surgical exploration that showed no evidence of a tumor and subsequently normal VMA excretion rates, pheochromocytoma proved to be unlikely. We recommend caution in making the diagnosis of pheochromocytoma within several months of cerebrovascular accident. (<i>JAMA</i>230:575-577, 1974)
Smoking cessation, decline in pulmonary function and total mortality: a 30 year follow up study among the Finnish cohorts of the Seven Countries Study
Authors: M Pelkonen, I-L Notkola, H Tukiainen, M Tervahauta, J Tuomilehto, A Nissinen
Journal: Thorax (2001)

BACKGROUND Permanent smoking cessation reduces loss of pulmonary function. Less is known in the long term about individuals who give up smoking temporarily or quitters with lower initial pulmonary function. Little is known also about the relationship between decline in pulmonary function and mortality. We examined these aspects and the association between smoking, decline in pulmonary function, and mortality. METHODS Two middle aged male Finnish cohorts of the Seven Countries Study and their re-examinations on five occasions during a 30 year period of follow up were analysed. RESULTS During the first 15 years (n=1007) adjusted decline in forced expiratory volume in 0.75 seconds (FEV 0.75 ) was 46.4 ml/year in never smokers, 49.3 ml/year in past smokers, 55.5 ml/year in permanent quitters, 55.5 ml/year in intermittent quitters, and 66.0 ml/year in continuous smokers (p&lt;0.001 for trend). Quitters across the entire range of baseline FEV 0.75 had a slower decline in FEV 0.75 than continuous smokers. Among both continuing smokers and never smokers, non-survivors had a significantly (p&lt;0.001) more rapid decline in FEV 0.75 than survivors. The adjusted relative hazard for total mortality was 1.73 (95% confidence interval (CI) 1.41 to 2.11) and 1.24 (95% CI 1.02 to 1.52) in the lowest and middle tertiles of decline in FEV 0.75 . Never smokers, past smokers, and quitters had significantly lower total mortality than continuous smokers, partly because of their slower decline in FEV 0.75 . CONCLUSION These results highlight the positive effect of smoking cessation, even intermittent cessation, on decline in pulmonary function. Accelerated decline in pulmonary function was found to be a risk factor for total mortality. The beneficial effect of smoking cessation on mortality may partly be mediated through a reduced decline in pulmonary function.
Prognosis in diabetic nephropathy.
Journal: BMJ (1989)

recommend a hydrolysate formula.The incidence and severity of eczema in the infants fed a casein hydrolysate formula were significantly reduced compared with those in infants fed conventional cows' milk or soy milk formulas.The incidence in the hydrolysate group was comparable with that in the breast fed infants whose mothers took dietary precautions during lactation, though the eczema was more severe.The incidence in the hydrolysate group was significantly lower than that in the breast fed group whose mothers were not on a restricted diet.In our prospective randomised study soy milk formula did not offer any preventive advan- tage in high risk infants, as also reported by others.' 6 1In conclusion, mothers of infants with a family history of atopy should avoid common allergenic foods while breast feeding.Alternatively, the infants should be fed a milk hydrolysate formula.
Some Problems of Wartime Neurology
Journal: JAMA (2017)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Thyroid hormone, osteoporosis, and estrogen
Authors: D. S. Cooper
Journal: JAMA (1994)

As noted by Schneider and colleagues<sup>1</sup>in this issue ofTHE JOURNAL, thyroid hormone (levothyroxine sodium) is one of the most frequently prescribed drugs in the United States. Postmenopausal women are particularly prone to develop hypothyroidism, thyroid nodules, and thyroid cancers and are therefore far more likely than men to be taking thyroid hormone, either for replacement therapy or suppression therapy.<sup>2</sup>Unfortunately, older women are also at high risk for progressive bone loss from thyroid hormone, as documented in a number of previous studies and summarized in the article by Schneider et al.<sup>1</sup>The risk of bone loss is greatest in those women taking larger thyroid hormone doses and seems to be minimal in women taking more modest doses.<sup>1</sup>Although the degree of skeletal demineralization observed in many studies places some patients below the fracture threshold in terms of their bone density, no study to date
Coxsackievirus and Adenovirus Infection
Authors: James J. Rahal
Journal: JAMA (1976)

The prearthritic manifestations of juvenile rheumatoid arthritis in a 16-year-old boy were associated with a rise in coxsackievirus B3 and A9 neutralizing antibody titers from 1:16 to ≥ 1:512, and 1:64 to 1:512, respectively. Recurrent polyarthritis followed and has persisted for three years. Adenovirus 7 was isolated from the pericardial fluid of a 9-year-old girl in whom juvenile rheumatoid arthritis then developed. Of 11 patients with acute, nonspecific, febrile arthritis subsequently studied, fourfold or greater antibody elevations occurred against coxsackieviruses in five, and against rubella and varicella-zoster virus in two. Antibody titers against other viral (and<i>Mycoplasma</i>) antigens remained stable. These findings suggest that coxsackieviruses, as well as other common viruses, may cause acute, nonspecific, febrile arthritis. In certain instances, such infection may be related to the development of juvenile rheumatoid arthritis. (<i>JAMA</i>235:2496-2501, 1976)
LIVER EXTRACTS IN ANEMIA
Journal: JAMA (1927)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Book Review Textbook of Medical Treatment by Various Authors . Edited by D. M. Dunlop, B.A. (Oxon.), M.D., F.R.C.P. (Edin.), L. S. P. Davidson, B.A. (Camb.), M.D., F.R.C.P. (Edin.), M.R.C.P. (Lond.), and J. W. McNee, D.S.O., D.Sc., M.D. (Glas.), F.R.C.P. (Lond.), with a foreword by A. J. Clark, B.A. (Camb.), M.D., D.P.H., F.R.C.P. (Lond.), F.R.S. 8°, cloth, 1127 pp., with 27 illustrations, and charts and tables. Baltimore: Williams &amp; Wilkins Company, 1939. $8.00.
Journal: New England Journal of Medicine (1940)
Muscle-specific knockout of PKC-λ impairs glucose transport and induces metabolic and diabetic syndromes
Authors: Robert V. Farese, Mini P. Sajan, Hong Yang, Pengfei Li, Steven Mastorides, William R. Gower, Sonali Nimal, Cheol Soo Choi, Sheene Kim, Gerald I. Shulman, C. Ronald Kahn, Ursula Braun, Michael Leitges
Journal: Journal of Clinical Investigation (2007)
Reply
Authors: I. Katayama, H. Yokozeki, K. Nishioka
Journal: British Journal of Dermatology (1996)

Journal Article Reply Get access I. Katayama, I. Katayama Department of Dermatology, Tokyo Medical and Dental University, 1‐5‐45 Yushima, Bunkyo‐ku, Tokyo, Japan Search for other works by this author on: Oxford Academic Google Scholar H. Yokozeki, H. Yokozeki Department of Dermatology, Tokyo Medical and Dental University, 1‐5‐45 Yushima, Bunkyo‐ku, Tokyo, Japan Search for other works by this author on: Oxford Academic Google Scholar K. Nishioka K. Nishioka Department of Dermatology, Tokyo Medical and Dental University, 1‐5‐45 Yushima, Bunkyo‐ku, Tokyo, Japan Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 135, Issue 3, 1 September 1996, Page 489, https://doi.org/10.1111/j.1365-2133.1996.tb01526.x Published: 01 September 1996
Preventing neonatal herpes
Authors: G. B. Feldman
Journal: JAMA (1985)

<h3>In Reply.—</h3> I thank Drs Smith and Krogh for their kind comments; I confess that I have occasionally resorted to Dr Caccamise's solution (and more often have wished that I had done so!). The rule I presented doesn't require a calculator with fresh batteries; the calculations were presented just to show the basis for my simple guideline: <h3>NINE DOUBLE-SPACED LINES OF FIFTY CHARACTERS WILL ALMOST ALWAYS BE LEGIBLE; EXCEED THAT ONLY AT RISK OF LOSS OF AUDIENCE.</h3> The corollary mentioned by Drs Smith and Krogh is a useful one, though. In glancing through the slides currently (dis)arrayed on my desk, I find it tough to read the ones with more than ten or 12 lines at normal reading distance. I wasn't familiar with the "rule of eight," as stated by Dr Smith. I did pull out my calculator to check and found that—if the guidelines to which he alludes are
DISEASE AND HOSPITALS OF THE INTERIOR OF SOUTH AFRICA.
Authors: NICHOLAS SENN
Journal: JAMA (1906)

The interior mountain plateau of South Africa has a healthful climate, and malaria, if it exist, is limited to circumscribed locations. No place along the East Coast is exempt from this disease, which prevails throughout the year, although it is much more frequent during the rainy season. Professor Koch has made the statement that in German East Africa the disease as a rule reaches its topographic limits at an altitude of 3,000 feet, and from what I have seen this rule applies to most parts of Africa. As soon as we reached this altitude we no longer saw the impress of malarial poisoning stamped on the faces of the people living on the coast, and the number of malarial patients in the hospital diminished with the increase of the altitude, being smallest in Johannesburg, which is situated nearly 6,000 feet above the level of the sea. At Victoria Falls, which
Obituaries
Journal: JAMA (1985)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Reply to Roderick C.N. van den Bergh, Massimo Valerio, Derya Tilki, and Giorgio Gandaglia’s Letter to the Editor re: Timothy J. Wilt, Tien N. Vo, Lisa Langsetmo, et al. Radical Prostatectomy or Observation for Clinically Localized Prostate Cancer: Extended Follow-up of the Prostate Cancer Intervention Versus Observation Trial (PIVOT). Eur Urol. In press. http://dx.doi.org/10.1016/j.eururo.2020.02.009
Authors: Timothy J. Wilt, Philipp Dahm, Michael K. Brawer
Journal: European Urology (2020)
Experimental Pacemaker Uses Rechargeable Batteries
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
LONDON
Journal: JAMA (1927)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Re: Grant D. Stewart, Fiach C. O’Mahony, Alexander Laird, et al. Carbonic Anhydrase 9 Expression Increases with Vascular Endothelial Growth Factor–Targeted Therapy and Is Predictive of Outcome in Metastatic Clear Cell Renal Cancer. Eur Urol. In press. http://dx.doi.org/10.1016/j.eururo.2014.04.007
Authors: Nils Kroeger, Allan J. Pantuck
Journal: European Urology (2014)
Reply
Authors: E El-Omar, K. McColl
Journal: Gut (1994)

Maternal cigarette smoking during pregnancy is associated with increased risk of perinatal morbidity and mortality. However, the mechanisms underlying adverse birth outcomes following prenatal exposure to cigarette smoke remain unknown due, in part, to the absence or unreliability of information regarding maternal cigarette smoke exposure during pregnancy. Our goal was to determine if placental cotinine could be a reliable biomarker of fetal cigarette smoke exposure during pregnancy. Cotinine levels were determined in placentas from 47 women who reported smoking during pregnancy and from 10 women who denied cigarette smoke exposure. Cotinine levels were significantly higher in placentas from women reporting cigarette smoking (median = 27.2 ng/g) versus women who reported no smoke exposure (2.3 ng/g, <i>P</i> &lt; 0.001). Receiver operating characteristic curve analysis identified an optimal cut point of 7.5 ng/g (sensitivity = 78.7%, specificity = 100%) to classify placenta samples from mothers who smoked versus those from mothers who did not. Among 415 placentas for which maternal cigarette smoking status was unavailable, 167 had cotinine levels &gt; 7.5 ng/g and would be considered positive for cigarette smoke exposure. Data from quantitative reverse-transcription polymerase chain reaction analyses demonstrated that in utero cigarette smoke exposure predicted by cotinine in placenta is associated with changes in the expression of xenobiotic-metabolizing enzymes in fetal tissues. <i>CYP1A1</i> mRNA in fetal lung and liver tissue and <i>CYP1B1</i> mRNA in fetal lung tissue were significantly induced when cotinine was detected in placenta. These findings indicate that cotinine in placenta is a reliable biomarker for fetal exposure and response to maternal cigarette smoking during pregnancy.