tbuckley/cabot-search huggingface dataset:
BEHRING'S NEW METHOD OF INOCULATION AGAINST DIPHTHERIA
Journal: JAMA (2013)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Ovarian Neoplasia in the Sprague-Dawley Rat
Authors: David J. Lewis
Journal: Environmental Health Perspectives (1987)

Macroscopic and microscopic characteristics of 210 spontaneous ovarian tumors from 7748 Sprague-Dawley rats are described. The tumors were classified as tubular adenoma, anaplastic adenocarcinoma, papillary cystadenoma, papillary cystadenocarcinoma, mesothelioma, sertoliform tubular adenoma, Sertoli's cell tumor, granulosa cell tumor, thecal cell tumor, polycystic sex cord/stromal tumor, and lipoid cell tumor. The histogenesis of the tumor types is discussed.
From the National Institutes of Health
Authors: E. Gordis
Journal: JAMA (1994)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
SMILE A WHILE
Journal: JAMA (1967)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Births in Herman Kiefer Hospital
Journal: JAMA (1941)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Levels of Toxic Metals in Marine Organisms Collected from Southern California Coastal Waters
Authors: Bruce A. Fowler, Rimmon C. Fay, Richard L. Walter, Robert D. Willis, William F. Gutknecht
Journal: Environmental Health Perspectives (1975)

Emission of toxic trace metals into southern California coastal waters has resulted in the extensive accumulation of the elements within marine sediments. The current study was undertaken to evaluate concentrations of trace metals in bottom-dwelling marine fauna collected from two sampling areas. Analyses carried out on muscle samples of the dover sole (Microstomus pacificus) and the crab (Cancer anthonyi) by proton-induced x-ray emission analysis showed considerable concentrations of arsenic and selenium. Samples of gonads, digestive gland, and muscle from the crab Mursia gaudichaudii analyzed by atomic absorption spectroscopy showed elemental concentrations in muscle similar to the crab Cancer anthonyi and much higher metal levels in gonad and digestive gland. These findings suggest the need for further studies concerning the relationship between emission of metals into the marine environment and their abundance in marine fauna.
Shall The Journal be Removed to Washington?
Authors: R. Harvey Reed
Journal: JAMA (1891)

THE VOICE OF OUR MEMBERS AS SHOWN BY A VOTE OF THE SAME ON THE QUESTION OF THE REMOVAL OF THE JOURNAL FROM CHICAGO TO WASHINGTON. As straws show which way the gentle zephyrs blow; Thus Votes, the will of our Association show! The agitation on the part of some of the Trustees, which contemplates a removal ofThe Journalof the Association from Chicago to Washington, was scarcely announced, before a general feeling of opposition was clearly evident in a large majority of the more active members of the entire Association—North, South, East and West. But how to obtain an expression from the members regarding such a movement, and, at the same time, put in force the will of the majority of the same under all the circumstances, was a perplexing question. The Association being made up of permanent members and delegates, the former having no vote and the
JAMA Journal Club
Journal: JAMA (1993)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Manuscripts Approved for JNCI, September-October 1973
Journal: JNCI Journal of the National Cancer Institute (1973)

Manuscripts Approved for JNCI, September-October 1973 Get access JNCI: Journal of the National Cancer Institute, Volume 51, Issue 5, November 1973, Page 1735, https://doi.org/10.1093/jnci/51.5.1735-c Published: 01 November 1973
Evaluation and Use of Epidemiological Evidence for Environmental Health Risk Assessment: WHO Guideline Document
Authors: WHO Working Group
Journal: Environmental Health Perspectives (2000)

Environmental health risk assessment is increasingly being used in the development of environmental health policies, public health decision making, the establishment of environmental regulations, and research planning.The credibility of risk assessment depends, to a large extent, on the strength of the scientific evidence on which it is based.It is, therefore, imperative that the processes and methods used to evaluate the evidence and estimate health risks are clear, explicit, and based on valid epidemiological theory and practice.Epidemiological Evidence for Environmental Health Risk Assessment is a World Health Organization (WHO) guideline document.The primary target audiences of the guidelines are expert review groups that WHO (or other organizations) might convene in the future to evaluate epidemiological evidence on the health effects of environmental factors.These guidelines identify a set of processes and general approaches to assess available epidemiological information in a clear, consistent, and explicit manner.The guidelines should also help in the evaluation of epidemiological studies with respect to their ability to support risk assessment and, consequently, risk management.Conducting expert reviews according to such explicit guidelines would make health risk assessment and subsequent risk management and risk communication processes more readily understood and likely to be accepted by policymakers and the public.It would also make the conclusions reached by reviews more readily acceptable as a basis for future WHO guidelines and other recommendations, and would provide a more rational basis for setting priorities for future research.
Drug Use in the Nursing Home
Authors: Susan W. Tolle
Journal: Annals of Internal Medicine (1996)

Letters15 March 1996Drug Use in the Nursing HomeSusan W. Tolle, MD and Paul Bascom, MDSusan W. Tolle, MDOregon Health Sciences University; Portland, OR 97201Search for more papers by this author and Paul Bascom, MDOregon Health Sciences University; Portland, OR 97201Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-124-6-199603150-00025 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:The article by Drs. Avorn and Gurwitz [1] highlights the overprescribing of many medications to nursing home residents. Within their data lies a second important problem. The authors acknowledge the potential underuse of “opioid analgesics in patients with metastatic cancer.” We argue that the underuse of opioids applies to diagnoses other than metastatic cancer. Medicine has a tradition of underprescribing opioids and other pain medications, particularly for patients who cannot speak clearly about their pain. For example, until recent years, newborns were not thought to experience pain, and surgical procedures were commonly done without anesthesia. When data ...References1. Avorn J, Gurwitz JH. Drug use in the nursing home. Ann Intern Med. 1995; 123:195-204. Google Scholar2. Rogers MC. Do the right thing: pain relief in infants and children. N Engl J Med. 1992; 326:55-6. Google Scholar3. Ferrell BA, Ferrell BR, Osterweil D. Pain in the nursing home. J Am Geriatr Soc. 1990; 38:409-14. Google Scholar4. Sengstaken EA, King SA. The problems of pain and its detection among geriatric nursing home residents. J Am Geriatr Soc. 1993; 41:541-4. Google Scholar5. Hurley AC, Volicer BJ, Hanrahan PA, Houde S, Volicer L. Assessment of discomfort in advance Alzheimer patients. Res Nursing Health. 1992; 15:369-77. Google Scholar Author, Article, and Disclosure InformationAuthors: Susan W. Tolle, MD; Paul Bascom, MDAffiliations: Oregon Health Sciences University; Portland, OR 97201 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byA Prospective Study of the Efficacy of the Physician Order Form for Life-Sustaining Treatment 15 March 1996Volume 124, Issue 6Page: 616KeywordsAnalgesicsAnesthesiaCodeineCognitive impairmentDementiaDrugsElderlyNursing homesOpioidsPressure ulcers ePublished: 15 August 2000 Issue Published: 15 March 1996 Copyright & PermissionsCopyright © 1996 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Legionnaires' disease in Vermont, May to October 1977
Authors: H. N. Beaty
Journal: JAMA (1978)

Thirty-two confirmed and 24 highly probable cases of Legionnaires' disease occurred in Vermont between May 1 and Oct 15, 1977. Confirmed cases had positive results for direct fluorescent antibody testing of lung tissue or fourfold rise in antibody titer. Highly probable cases had one elevated titer (≥1:256) and a compatible illness. Forty-eight (86%) had underlying chronic disease, and 22 (39%) were immunocompromised. Prominent early symptoms were fever, cough, chills, and malaise. All but one patient had verified pneumonia. Courses ranged from a pneumonia not requiring hospitalization to respiratory failure necessitating support with mechanical ventilation. Seventeen patients died. Although the clinical presentation was variable, rapid development of high fever and leukocytosis together with negative cultures of lower respiratory tract secretions strongly suggested the diagnosis in an epidemic setting. (<i>JAMA</i>240:127-131, 1978)
AARP's call to arms: 'Reform health care—now!'
Journal: JAMA (1992)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Association of age with breast cancer clinical and pathological factors: Analysis of Turkish National Breast Cancer Registry.
Authors: Mustafa Benekli, Kadri Altundag, Esra Dumanli, Abdurrahman Isikdogan, Aziz Karaoglu, Salim Basol Tekin, Berna Oksuzoglu, Murat Kocer, Alper Sevinc, Melih Cem Boruban, Hande Turna, Ruchan Uslu, Ozgur Ozyilkan, Bulent Yalcin, Ugur Coskun, Saadettin Kilickap, Gamze Gokoz Dogu, Banu Ozturk, Mahmut Gumus, Suleyman Buyukberber
Journal: Journal of Clinical Oncology (2015)

e12653 Background: Breast cancer (BC) has unique clinical and biological variables in young and elderly patients. BC in young individuals tends to behave more aggressively with subsequent unfavorable outcome. Conversely, elderly pts usually have a more indolent BC course. We aimed to analyze the effect of young and older age on the natural course of BC in Turkish pts. Methods: Pts presenting to medical oncology clinics were prospectively registered after October 2012 in 28 centers. Patients were stratified according to age: young ≤ 35 yrs and elderly ≥ 65 yrs. The association of age with patient demographics and pathologic characteristics were evaluated. Results: 13749 pts (128 males [0.9%]) were registered. Median age was 53 yrs (20-93). Pts ≤ 35 and ≥ 65 constituted 4.2% and 20.9% of the whole population, respectively. Rate of male BC was tripled in pts ≥ 65 yrs compared to the ones < 65 yrs of age (2% vs 0.7%, p < 0.001). Histopathology and the grade of the tumors were similar. Stage distribution was also similar in pts ≥ 65 vs < 65 (stages I-IV in elderly: 17.8%, 50.6%, 23% and 8.5%,respectively, as compared to pts < 65: 17.1%, 48.5%, 26.5% and 7.9%, respectively). ER positivity was higher in pts ≥ 65 vs < 65 yrs (77.6% vs 75.2%, p < 0.001) with similar PR positivity rates. In contrary, Her2 was positive in a greater proportion of patients < 65 yrs compared to pts ≥ 65 (28% vs 21.7%, p < 0.001). Distribution of BC molecular subgroups was similar. Analysis of pts < 35 yrs revealed similar distribution of gender (p = 0.272) and disease stage (p = 0.571). But, proportion of grade 3 pts were higher in pts < 35 yrs (37.8% vs 30.0%, p = 0.005). Similarly, pts < 35 yrs tended to have negative ER (27.4% vs 24.3%) and negative PR (32.7% vs 28.7%) and amplified Her2 (36.5% vs 2.6%) (p < 0.001). Moreover, frequencies of Her2-enriched type (12.3% vs 8.8%) and triple-negative type (13% vs 11.5%) BC were higher in pts < 35 yrs of age (p = 0.016). Conclusions: Our results confirm previous observations reporting more aggressive tumor biology with higher rates of ER/PR negativity and Her2 amplification associated with higher tumor grade in young pts.
The Autopsy
Authors: John Prutting
Journal: JAMA (1973)

<h3>To the Editor.—</h3> I have read with concern the dissenting opinions of Drs. Mark C. Wheelock and Juan A. Hernandez (223:1157, 1973) in response to my letter (222:1556, 1972) on the inadequate level of autopsies in American medicine today. The thinking expressed in these communications reflects precisely<i>why</i>the Joint Commission on Accreditation of Hospitals is doing disservice to medical progress by abolishing a minimum autopsy percentage for hospital approval. We could ask for no better proof of the fact that many pathologists, small community hospitals, and reluctant physicians<i>need</i>such a standard because their own motivation for (and willingness to learn from) autopsies is lacking. Dr. Wheelock contends that "most states have a minimum autopsy requirement, around 20% or more, before they, in turn, issue an annual approval of hospitals within their confines." This does not concur with my information. Even if it did, what purpose is served by
TO MEMBERS OF THE ASSOCIATION.
Journal: JAMA (1894)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Illustrations of the Different Forms of Insanity
Authors: W. H. O. Sankey
Journal: BMJ (1863)

IN the case last given, there was a predisposition to insanity in the patient's family.The father died of insanity, said to have been produced by drink.The next case is chosen as an instance in which the heredi- tary tendency was still more marked, and the evidence of its existence more positive.CASE III.
Surgical Pathology
Journal: JAMA (2000)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Ad Moratorium
Authors: Mike Mitka
Journal: JAMA (2011)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal