tbuckley/cabot-search huggingface dataset:
Experimental Diabetes —A New Type Reported
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Psychoactive drug use and AIDS
Journal: JAMA (1990)

<h3>To the Editor.—</h3> The June 16 issue of<i>JAMA</i>presented a report from the Multicenter AIDS Cohort Study entitled "No Evidence for a Role of Alcohol or Other Psychoactive Drugs in Accelerating Immunodeficiency in HIV-1—Positive Individuals."1 In this study, results obtained from a questionnaire about, for the most part, illicit drug use were compared with laboratory test results of human immunodeficiency virus type 1 antibody testing and peripheral blood lymphocyte phenotyping. Apparently, there was no attempt to measure urine or plasma drug levels. Drug verification is common practice in most medical fields, eg, psychiatry, internal medicine, pediatrics, and emergency medicine, and in many employment environments and sporting endeavors. Although history taking is a valuable tool, no conclusion of this nature can be drawn without acceptable verification.
EDITORIAL NOTES.
Journal: JAMA (1891)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 4430: Simulating delivery of TTFields to the infratentorium in patients with brainstem gliomas
Authors: Marigdalia K. Ramirez-Fort, Brittany Cross, Ariel Naveh, Shearwood McClelland, Melissa Mendez, Roberto Santiago, Sean S. Mahase, Jaime Matta, Ze'ev Bomzon, Christopher S. Lange
Journal: Cancer Research (2019)

Abstract Purpose/Objective(s): TTFields are FDA-approved for the treatment of recurrent and newly diagnosed Glioblastoma (GBM) in the supratentorial brain. The EF-14 trial showed that combining TTFields with adjuvant chemo-radiation leads to a significant increase in overall survival compared to adjuvant chemo-radiation alone. High-grade gliomas also occur in the infratentorium and brainstem of pediatric and adult patients. Brainstem gliomas have a median survival of 9 to 11 months, necessitating the exploration of novel treatment combinations, such as delivering TTFields to the infratentorial brain. We recently showed in a simulation-based study that TTFields can be successfully delivered to the infratentorium. Effective delivery was achieved by placement of the arrays on the vertex, bilateral posterolateral occiput, and superior-posterior neck; the array placement results in TTFields at therapeutic intensities throughout the brainstem and cerebellum of realistic computational head models. The previous simulation-based study was performed using realistic computational models of healthy individuals; it did not provide detailed insight into field distributions within tumor tissue located in the infratentorium. Here, we aim to expand the results of this previous study, by simulating the delivery of TTFields to the infratentorium of adult and pediatric patients with high-grade brainstem gliomas. Materials/Methods: A realistic computational model was created using MRI data of adult and pediatric patients with high-grade brainstem gliomas. Transducer arrays were placed on the model and the delivery of TTFields to the infratentorial brain was then simulated using a commercial numerical solver. The electric field distribution in the supratentorium, infratentorium, and within the tumor were derived from the simulations, and the dose in the tumor analyzed. Results: The distribution of calculated isofield lines demonstrates effective delivery of TTFields to infratentorial brain tumors. Conclusion: Our results provides rationale for clinically investigating the utility of TTFields in treating infratentorial high-grade gliomas. Citation Format: Marigdalia K. Ramirez-Fort, Brittany Cross, Ariel Naveh, Shearwood McClelland III, Melissa Mendez, Roberto Santiago, Sean S. Mahase, Jaime Matta, Ze'ev Bomzon, Christopher S. Lange. Simulating delivery of TTFields to the infratentorium in patients with brainstem gliomas [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 4430.
Hepatitis E virus genotype 3 subtype dependent clinical outcomes in Belgium 2010–2018
Authors: Michael Peeters, Thomas De Somer, Sofieke Klamer, Frederik Nevens, Jean-Pierre Delwaide, Peter Stärkel, Philippe Willems, Stéphane De Maeght, Christophe Moreno, Marc Van Hoof, Isabelle Colle, Christophe Van Steenkiste, Filip Janssens, Jos Van Acker, Astrid Marot, Emmanuel Bottieau, Marijke Reynders, Chantal De Galocsy, Luc Lasser, Matthias Steverlynck, Jeroen Maus, Wim Verlinden, Anja Geerts, Marie Gallant, Van Outryve Steven, Hendrik Reynaert, Jean-Pierre Mulkay, Jochen Decaestecker, Vanessa Suin, Sergio Negrin-Dastis, Jan Beyls, Jochen Nijs, Juul Boes, Steven Van Gucht, Thomas Vanwolleghem
Journal: Journal of Hepatology (2020)
Ending Lives
Authors: Burton C. Einspruch
Journal: JAMA (1989)

All too infrequently, physicians probe the philosophical underpinnings of their profession. Periodically, however, there is increased professional awareness of sociomedical issues, usually subsequent to periods of intense public involvement. Questions raised by the Karen Quinlan case, thalidomide babies, or, currently, abortion and the acquired immunodeficiency syndrome are prime examples. <i>Ending Lives</i>is a provocative book that examines the philosophical positions addressing suicide and euthanasia. Both are major issues confronting contemporary society and are divisive in nature, partially owing to misunderstanding of complexities and the ease of developing polar positions. The aversion to suicide is so great in the western world that until the mid-19th century, suicide was regarded by the law as a crime ranked with homicide or murder (p 17). Only in the latter half of our century have most persons regarded the typical suicide victim as someone either psychologically ill or "in need of help." In opting for
Recombinant erythropoietin and Medicare payment
Authors: P. W. Eggers
Journal: JAMA (1991)

<h3>In Reply.</h3> —The Pennsylvania Hospital Effectiveness Reports are presented by hospital, but their risk models are patient-specific. Thus, it was appropriate for me to test for biases using the patient (not the hospital) as the unit of observation. Nonetheless, Dr Brewster and Ms Throop and Drs Hartz and Van Ruiswyk wish to know how important my findings are when making interhospital comparisons. This depends on the patient characteristics at the hospitals being compared. If patients with a given condition (such as AMI) were randomly admitted to different hospitals, the average risks of these cases would be the same at each hospital. Risk adjustment would then be unnecessary and bias inconsequential. The need for models to make unbiased estimates of the risk of a given outcome for patients at the hospital level increases as patients with a given condition at hospitals become more diverse in their patient characteristics. Brewster and Throop
THE WASSERMANN TEST AND ITS LIMITATIONS IN DIAGNOSIS AND TREATMENT
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Publications du Progres Medicale.
Journal: JAMA (1896)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Obituary Listing
Journal: JAMA (1991)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Equity of access: Consent interpretation program at Princess Margaret Cancer Centre (PM) in Canada.
Authors: Jasmine Grant, Lindsay Philip, Grace Eagan, Elizabeth Abraham, Pamela Degendorfer, Amit M. Oza
Journal: Journal of Clinical Oncology (2014)

e17516 Background: Toronto is a multicultural city with over 160 languages spoken by patients. Since 2010, University Health Network policy has required that professional medical interpreters are utilized when obtaining informed consent from patients with limited English proficiency (LEP). The availability and cost could be a deterrent for clinical trial participation, especially when funding is limited as in investigator initiated trials or cooperative group trials. In order to ensure that LEP patients have the same access to clinical trials as individuals who do not face language barriers, to protect the rights and safety of LEP patients involved in clinical trials, and ultimately improve patient outcomes, adherence to this policy across all trials regardless of funding level needs to be ensured. Metrics were collected to monitor the use of professional interpreters to see if more LEP patients are approached for trials. Methods: A collaboration between the PM Cancer Clinical Research Unit (CCRU) and Interpretation and Translation Services (ITS) led to a 6month pilot that was initiated with full access to interpretation services for all clinical trial patients in November 2012. The CCRU provided training to interpreters on clinical trials and GCP to improve the efficiency of the interpreted consent process. Interpreters prepared template consent forms based on those provided by the ethics boards to cut back on preparation time and costs when delivering a sight translation of study specific consent forms. Badge tags describing how to order ITS services were created and trials staff were trained on the process. The project was discussed with the two research ethics boards of record. Results: In the 6 month pilot, usage of professional interpreters in trials increased by 16%. A staff satisfaction survey is pending. Conclusions: The project is being expanded as it met its prime objective of increase in use by clinical trial patients with LEP. This project ensures that accurate information is received by all patients contemplating participating in or already enrolled on trials, that all patients have the same level of access to treatment, and that there is equity of access for all patients irrespective of their English proficiency.
Landscape
Authors: M. Therese Southgate
Journal: JAMA (2006)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Serum Bile Acids and Alanine Aminotransferase Concentrations
Authors: John Milton Mishler
Journal: JAMA (1981)

Indirect tests of liver function such as determinations of concentrations of alanine aminotransferase (ALT) and conjugated bile acids (BA) have been advocated as indicators of both the infectivity of the blood of donors in transmitting non-A, non-B (NANB) hepatitis and of the onset, severity, and duration of this disease in recipients. We therefore compared the predictive value of concentrations of ALT and postprandial concentrations of BA in the blood of 311 donors and in the blood of 41 recipients in whom either NANB or type B hepatitis developed after transfusion. Our results demonstrated that higher than normal concentrations of ALT (&gt;45 IU/L) in the blood of donors were generally accompanied with normal concentrations of BA (&lt;6 μmole/L). and, therefore, concentrations of ALT may be more useful in predicting the infectivity of donor blood in transmitting NANB hepatitis. In addition, concentrations of ALT, compared with BA concentrations, were a significantly better indicator of the onset, severity, and duration of the disease in recipients in whom NANB hepatitis developed after transfusion. In recipients who had posttransfusion type B hepatitis, serum concentrations of ALT were significantly better indicators of the onset and severity of the disease than concentrations of BA. (<i>JAMA</i>1981;246:2340-2344)
Arsenic in the drinking water of the city of Antofagasta: epidemiological and clinical study before and after the installation of a treatment plant
Authors: J M Borgoño, P Vicent, H Venturino, A Infante
Journal: Environmental Health Perspectives (1977)

This is a second report of epidemiological and clinical investigation, related to the arsenic health problem, unique in the world, occurring in the city of Antofagasta, Chile.The arsenic problem originates in the chronic contamination of water supply in the city during 12 years.This phenomena, investigated clinically and epidemiologically and first reported in 1971, prompted the installation of a water treatment plant.This report aims to evaluate the working efficiency of the plant.The study was carried out through the examination of arsenic content in hair and nail clipping samples of the inhabitants of Antofagasta and the determination of this element in cultivated vegetables and carbonated beverages.Also a clinical study in school children, looking for cutaneous lesions attributed to arsenicism, was made.Results are encouraging.They reveal that contamination persists but in significantly lower levels.
THE PHYSICIAN IN OREGON.
Journal: JAMA (1895)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
MASSIVE DOSES OF ALKALI IN TWO CASES OF IMPENDING DIABETIC COMA
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Book Listings
Journal: Annals of Internal Medicine (2002)

Book Listings19 March 2002Book ListingsSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-136-6-200203190-00024 SectionsAboutFull Text ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail CardiologyAuscultation Skills: Breath and Heart Sounds2nd edition. Springhouse. 268 pages. Springhouse, PA: Springhouse Corporation; 2002. $50.00. ISBN 1582551588. Order phone 800-588-7738.Cardiac Arrhythmias 2001A Raviele, ed. 657 pages. New York: Springer-Verlag; 2002. $109.00. ISBN 8847001609. Order phone 800-777-4643.Cardiology: Current PerspectivesG Jackson, ed. 404 pages. Philadelphia: Taylor & Francis; 2002. $99.00. ISBN 185317629X. Order phone 800-821-8312.Catheter Ablation of Arrhythmias2nd edition. DP Zipes and M Haissaguerre, eds. 432 pages. Armonk, NY: Futura; 2002. $98.00. ISBN 0879934980. Order phone 800-877-8761.Congenital Heart Disease in the AdultWM Gersony and MS Rosenbaum. 304 pages. New York: McGraw-Hill; 2002. $99.00. ISBN 0070329095. Order ... Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 19 March 2002Volume 136, Issue 6Page: B1KeywordsComputed axial tomographyHealth careMilkPrevention, policy, and public healthRacial and ethnic issues ePublished: 19 March 2002 Issue Published: 19 March 2002 Copyright & PermissionsCopyright © 2002 by American College of Physicians. All Rights Reserved.Loading ...