ADRENAL HORMONE THERAPY IN VIRAL HEPATITIS. II. THE EFFECT OF CORTISONE IN THE ACUTE DISEASE
Authors: A S EVANS, H SPRINZ, R S NELSON
Journal: Annals of Internal Medicine (1953)

Article1 June 1953ADRENAL HORMONE THERAPY IN VIRAL HEPATITIS. II. THE EFFECT OF CORTISONE IN THE ACUTE DISEASEALFRED S. EVANS, HELMUTH SPRINZ, ROBERT S. NELSONALFRED S. EVANSSearch for more papers by this author, HELMUTH SPRINZSearch for more papers by this author, ROBERT S. NELSONSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-38-6-1134 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn the preceding paper1it has been shown that administration of adrenocorticotropic hormone (ACTH) to 20 patients with acute viral hepatitis was associated with symptomatic improvement and a rapid initial drop in serum bilirubin as compared with control patients. This effect on bilirubinemia became progressively less marked as the drug was continued. The eosinophil response was, in general, poor. The average total duration of illness was not materially affected. It seemed possible that adrenal cortical exhaustion was responsible in part for these phenomena, and that direct substitution therapy with cortisone might be more effective and at the same time lessen...Bibliography1. EvansSprinzNelson ASHRS: Adrenal hormone therapy in viral hepatitis. I. The effect of ACTH in the acute disease, Ann. Int. Med. 38: 1115-1133, 1953. LinkGoogle Scholar2. KassFinland EHM: The role of adrenal steroids in infection and immunity, New England J. Med. 244: 464-470 (March 29) 1951. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication December 2, 1952.From the Hepatitis Center, 98th General Hospital, U. S. Army, Europe.†Present address: Department of Preventive Medicine and Student Health, University of Wisconsin, School of Medicine, Madison, Wisconsin.‡Cholesterol suspension was kindly furnished by Merck and Co., Rahway, New Jersey. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byUse of immunosuppression in non-transplant hepatologyThe detrimental effects of adrenocorticosteroid therapy in HBsAg-positive chronic active hepatitis: Fact or artifact?Nonassociation of Adrenocorticosteroid Therapy and Peptic UlcerVirushepatitisRed Cell Survival Estimated by Radioactive Chromium in Hepatobiliary DiseaseProphylaxis in patients receiving adrenal steroid therapyCortisone effect in stages of hepatic injury. A cytochemical, autoradiographic, and histologic studyCorticosteroids for Infections* *Reprinted from The Lancet, October 22, 1960, pp. 913-914.Corticosteroids for InfectionsNightingale and ListerHepatitis infectiosa (Virushepatitis)The Hepatic Metabolism of Adrenocortical Steroids and Some Clinical Implications ThereofSerum enzymes (transaminases, phosphoglucomutase, fumarase) in viral hepatitis during prednisone (δ1-cortisone) therapyACTH-treatment of Acute Viral HepatitisThe Use of ACTH and Adrenocorticosteroids in Diseases of the Digestive SystemThe Use of Cortisone and ACTH in Liver DiseasePossible Effect of Hydrocortisone on Bilirubin Excretion by the LiverThe Use of the Adrenocorticosteroids in GastroenterologyPRESENT INDICATIONS FOR CORTISONE THERAPY IN ACUTE VIRAL HEPATITIS*ROBERT S. NELSON, M.D., F.A.C.P.Die Serumlipoide unter besonderer Ber�cksichtigung Des PlasmalogensManagement of the Patient with Acute (Virus A) HepatitisWHAT IS IMPORTANT IN THE TREATMENT OF LIVER DISEASE*I. FRANK TULLIS, M.D., F.A.C.P."CHOLANGIOLITIC HEPATITIS," WITH SPECIAL REFERENCE TO ITS PHYSIOPATHOLOGIC CONCEPT, DIAGNOSIS AND THERAPY*EMANUEL W. LIPSCHUTZ, M.D., F.A.C.P., DAVID CAPSON, M.D.Adrenal hormone therapy in viral hepatitisTreatment of Acute Hepatitis With Cortisone and AntibioticsViral hepatitis and its risk from blood and plasma transfusionsCORTISONE IN THE TREATMENT OF INFECTIOUS HEPATITIS*TYRON E. HUBER, ANDREW T. WILEYOCCURRENCE OF ACCUMULATION OF FAT IN THE LIVER AND ITS RELATION TO EXCESS WEIGHT GAIN IN PATIENTS CONVALESCING FROM VIRAL HEPATITIS*ARTHUR R. COLWELL JR., M.D.Choleretic Action of CortisoneADRENAL HORMONE THERAPY IN VIRAL HEPATITIS. III. THE EFFECT OF ACTH AND CORTISONE IN SEVERE AND FULMINANT CASES*ALFRED S. EVANS, HELMUTH SPRINZ, ROBERT S. NELSON 1 June 1953Volume 38, Issue 6Page: 1134-1147KeywordsAdrenocorticotropic hormoneEosinophilsHepatitisHepatitis AHepatitis DHepatitis EHormonal therapyHormonesPreventive medicineSurgeons ePublished: 1 December 2008 Issue Published: 1 June 1953 PDF downloadLoading ...