tbuckley/cabot-search huggingface dataset:
Reports of Societies
Authors: Arthur Burgless, F Eng
Journal: BMJ (1900)

of membranes were presenting, and, on rupturing them, the feet of a second child were seized, and the rest of the body slowly delivered.Haemorrhage was now more profuse but the uterus seemed fairly well contracted, and the placenta of the first child was found to be in the vagina.It was removed, and after eight or ten minutes, as the bleeding was not ceasing, the left hand was again introduced into the uterus and the second placenta-which was partially unseparated, and whose attach- ment extended into the inferior zone of the uterus-was care- fully extracted.The patient was now very much exhausted, 50 30 minims of ether were injected hypodermically along with fi of a grain of ergotinin, and a firm binder applied.Meat juice and brandy were afterwards administered at in- tervals and the patient was apparently steadily recovering, when, on making a movement to turn in bed, she sud- denly -expired, about six hours after the termination of the labour.Obstetricians differ somewhat as to the rarity of this condi- tion.Angus Macdonald puts it at I in 44,500 cases of labour.Barnes says it is not uncommon, and Winckel states that plural pregnancy predisposes to placenta prievia, the accident in his experience being relatively four times more frequent in plural than in single pregnancy.The risks to the mother must be much more grave when the condition coexists with a plural pregnancy, as one could not always adopt a mode of treatifient which, under certain circumstances, must be very satisfactory-that of separating the placenta entirely, and giving the patient time to react from the effects of hiemorrhage before emptying the uterus.
Methodology for Statistical Analysis of SENCAR Mouse Skin Assay Data
Authors: Judy A. Stober
Journal: Environmental Health Perspectives (1986)

Various response measures and statistical methods appropriate for the analysis of data collected in the SENCAR mouse skin assay are examined. The characteristics of the tumor response data do not readily lend themselves to the classical methods for hypothesis testing. The advantages and limitations of conventional methods of analysis and methods recommended in the literature are discussed. Several alternative response measures that were developed specifically to answer the problems inherent in the data collected in the SENCAR bioassay system are described. These measures take into account animal survival, tumor multiplicity, and tumor regression. Statistical methods for the analysis of these measures to test for a positive dose response and a dose-response relationship are discussed. Sample data from representative initiation/promotion studies are used to compare the response measures and methods of analysis.
Medico-Ethical
Journal: BMJ (1907)

Thank you for your interest in spreading the word about The BMJ.NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address. Username * Your Email * Send To * You are going to email the following Medico-Ethical Your Personal Message CAPTCHA This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Paraquat toxicity.
Authors: S. S. Brown, P. F. Gibson
Journal: BMJ (1970)

questioning.The story of unexplained abdominal pain in the mother or other members of the family tends to support the diagnosis.Treatment with antidepressants, either the tricyclic group or monoamine oxidase inhibitors, is frequently effective in eliminating the abdominal discomfort.In most cases regardless of age the relief is permanent unless there is renewed stress causing repeated anxiety in the child.The condition may be disabling, since the depressed child cannot function adequately either socially or at school.The underlying emotional problems often remain unsuspected, and frequent short absences from school lead to poor school work and antipathy on the part of the teachers.There is reluctance to use antidepressant drugs in children, but in this type of recur- rent abdominal pain they are certainly no more dangerous than a laparotomy and may be much more beneficial.-Weare, etc.,
Second Biennial Gordon Research Conference on Hormonal Carcinogenesis
Journal: JNCI Journal of the National Cancer Institute (1987)

Second Biennial Gordon Research Conference on Hormonal Carcinogenesis Get access JNCI: Journal of the National Cancer Institute, Volume 78, Issue 2, February 1987, Page 398, https://doi.org/10.1093/jnci/78.2.398-d Published: 01 February 1987
Exiled for Lese Majestie.
Journal: JAMA (1898)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Preventive Aspects of Chronic Disease: Conference Proceedings, March 12-14, 1951, Chicago, Illinois.
Journal: JAMA (1953)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Aromatic Hydrocarbon Receptor Polymorphism: Development of New Methods to Correlate Genotype with Phenotype
Authors: Andrew Maier, Jana Micka, Kevin Miller, Timothey Denko, Ching-Yi Chang, Daniel W. Nebert, Alvaro Puga
Journal: Environmental Health Perspectives (1998)

Differential CYPlAl inducibility, reflecting variations in aromatic hydrocarbon receptor (AHR) affinity among inbred mouse strains, is an important determinant of environmental toxicity.We took advantage of the Air polymorphism in C57BL16 and DBA/2 mice to develop an oligonu- deotide-hybridization screening approach for the rapid identification of DNA sequence differ- ences between Air alleles.Oligonudeotides containing single-base changes at polymorphic sites were immobilized on a solid support and hybridized with C57BL/6 or DBA/2 AHR cDNA radi- olabeled probes.The observed hybridization patterns demonstrate that this approach can be used to detect nudeotide differences in the Air coding region with very high accuracy.In paral- lel experiments, we used a yeast two-hybrid system to assess phenotypic differences in AHR function.AHR activation, as measured by 13-galactosidase reporter activity in Saceharomyces cerevisiae strain SFY526, was determined following treatment with varying doses of the AHR ligand P-naphthoflavone (BNF).We found that the C57BL16 AHR has about a 15-fold higher affinity for BNF than the DBAI2 AHR, in much better agreement with results reported for whole-aii- mal studies than the values observed by in vitro ligand-binding assays.Using C57BLI6 and DBA/2 AHR chimeric proteim, we also confirmed the previously reported observation that an A375V change is principally responsible for the high-to low-affinity AHR phenotype.There has been no straightforward method to reliably and reproducibly phenotype large numbers of humans for CYPlAl inducibility or AHR affinity.Screening human AHR cDNAs by oligonudeotide-hybridization and yeast two-hybrid methodologies will be invaluable for the rapid and unequivocal determination ofchanges in DNA sequence and receptor-ligand affinities associated with human AHR polymorphisms.
Abstract 17817: The Incidence and Mortality Risk of Acute Thoracic Aortic Dissection: Results From a Nationwide Population-based Study
Authors: Inga H Melvinsdottir, Sigrun H Lund, Bjarni A Agnarsson, Kristinn Sigvaldason, Tomas Gudbjartsson, Arnar Geirsson
Journal: Circulation (2015)

Introduction: Acute thoracic aortic dissection is a potentially lethal disease associated with high morbidity, however, contemporary data on incidence and mortality risk are lacking. Utilizing a nationwide data comprising the Icelandic population we aimed to determine the incidence, mortality and the time-dependent mortality risk of acute thoracic aortic dissection. Methods: Data was retrospectively collected using hospital discharge registries in Iceland from 1992-2013 as well as autopsy database from Medical Examiner Office. To capture all cases diagnostic codes for dissection (ICD-9: 441.1 and ICD-10: I71.0) were queried as well as for aortic aneurysm and arterial dissection. Total of 1811 charts were reviewed resulting in 153 confirmed diagnoses of acute thoracic aortic dissection. Demographics, medical history, risk factors and clinical symptoms were collected for all patients. Incidence was calculated using age and gender specific information provided by National Statistics Iceland. Results: Age and gender-adjusted incidence of acute thoracic aortic dissection was 2.5/100,000/year and no significant change in incidence was observed. The mean age was 66.9±13.6 years, 61% (94/153) were males and 66% (101/153) were Stanford type A. Of all patients diagnosed with dissection 18% (27/153) died prior to hospital arrival while the risk of death for all patients that arrived alive to a hospital was 21% (27/126) within 24 hours and 45% (57/126) at 30 days. Predictors for short-term mortality included female sex, renal disease and family history of dissection. The overall 10-year survival was 39% of which negative predictors included age, coronary artery disease, renal disease, peripheral vascular disease and family history of dissection. During the course of the study the 30-day mortality rate decreased by 0.96/year, (95% CI: 0.92- 0.99) and the 10-year survival improved significantly (p=0.04). Conclusions: Acute thoracic aortic dissection is uncommon but a lethal condition where two thirds of patients die within 30 days of the index event. The incidence remained constant but a decline in short-term mortality and increased long-term survival was observed indicating improved overall outcome in patients diagnosed with this complex condition.
Carroll Behrhorst, MD: lessons from the third world
Journal: JAMA (1980)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
LOOKING FORWARD TO SCHOOL
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Aortic Arch Reconstruction by Transluminally Placed Endovascular Branched Stent Graft
Authors: Kanji Inoue, Hiroaki Hosokawa, Tomoyuki Iwase, Mitsuru Sato, Yuki Yoshida, Katsuya Ueno, Akiyoshi Tsubokawa, Terumitsu Tanaka, Shunichi Tamaki, Takahiko Suzuki
Journal: Circulation (1999)

Background —Recently, thoracic aortic stent grafting has emerged as an alternative therapeutic modality for patients with thoracic aortic aneurysms and aortic dissections. However, its application has been limited to descending thoracic aortic aneurysms distal to the aortic arch. We report our initial clinical experience of endovascular branched stent graft repair for aortic arch aneurysms. Methods and Results —Endovascular grafting with Inoue branched stent grafts was attempted for 15 patients with thoracic aortic aneurysms and aortic dissections under local anesthesia (n=14) or general anesthesia (n=1). Single-branched stent grafts were used in 14 patients, and a triple-branched stent graft in one. The branched stent grafts were delivered through a 22F or a 24F sheath under fluoroscopic guidance and implanted across the aneurysmal aortic arch. In 2 patients, the single-branched stent graft did not pass through the 22F sheath used. Complete thrombosis of the aneurysm was ultimately achieved in 11 patients (73%). Of 4 persistent leaks, 1 minor leak spontaneously thrombosed and 1 major leak was successfully treated by additional straight stent graft placement. In 1 patient, the right external iliac artery ruptured during the withdrawal of the sheath and was successfully repaired by the implantation of a straight stent graft. One patient with severe stenosis of the aortic graft section was successfully managed by additional stent deployment. Peripheral microembolization to a toe occurred in 1 patient, and cerebral infarction occurred in 1 other patient. Two patients who had failed to receive endovascular stent grafts died during an average follow-up of 12.6 months, 1 of pneumonia and the other of rupture of a concomitant abdominal aortic aneurysm. Conclusions —This report demonstrates the technical feasibility of endovascular branched stent graft repair for aneurysms located at the aortic arch. Careful, longer follow-up and further extensive clinical trials are awaited toward establishing this technique as a recommendable alternative to surgical treatment of thoracic aortic aneurysms.
NEW TONSIL FORCEPS
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 4187: Racial disparities in kidney cancer incidence across South Texas, Texas, and United States using TCR, SEER and NPCR registries (2004-2014)
Authors: Casey Perez, Pankil K. Shah, Aaron Mathews, Edgar Munoz, Alex Bokov, Dharam Kaushik, Joel Michalek, Amelie Ramirez, Ronald Rodriguez, Dimpy P. Shah
Journal: Cancer Research (2019)

Abstract Introduction: Despite overall decrease in incidence of cancers in U.S., kidney cancer is one out of the only seven cancers with increasing incidence. Limited research has been conducted using national, state-wide, and regional data, especially comparing racial and ethnic disparities in incidence and outcomes for kidney cancer. Methods: Kidney cancer incidence and outcomes from 2004 to 2014 were compared using Texas Cancer Registry, National Program for Cancer Registries, and Surveillance, Epidemiology and End Results. Age-adjusted incidence rates (per 100,000 population) and temporal trends, reporting sources, diagnosis, patient and tumor characteristics between Hispanics and Non-Hispanic Whites (NHWs) were compared for each state. The Kaplan-Meier method was used for relative survival analyses, which were limited to Texas due to data availability. Results: A total of 566,716 patients were identified. The temporal trend shows a sustained increase in kidney cancers in U.S. and a consistently higher incidence in TX and South Texas (STX) over the past decade, with Hispanics in particular having the highest annual percent change (APC) among the 20-29 year old age group (5.3 in U.S. and 7.7 in TX, respectively). Age-adjusted kidney cancer incidence was 26.2 in STX, 24.5 in TX and 21.8 in U.S. Both males and females had a higher incidence in STX and TX compared to U.S. (35.1, 32.5 vs. 29.6 for males and 18.8, 17.9 vs.15.2 for females). Overall, Hispanic males in STX had the highest kidney cancer incidence (37.7) throughout U.S. The difference in incidence rate in Hispanics compared to NHWs was significant in STX (4.9) and TX (3.4), compared to U.S. (-0.9). Tumor grade was only available in 60% of cancers in TCR compared to 70% in U.S. Despite localized tumor stage being the most common presentation for all regions, the 5-year survival was lower in Hispanics compared to NHWs in STX (68% vs. 73%) and TX (69% vs. 71%). Conclusions: Kidney cancer rates were higher in STX and TX when compared to U.S., especially among Hispanic males. Relative 5-year survival between Hispanics and NHWs were similar in TX and STX. Improvement in cancer reporting and detailed studies examining causes for racial/ethnic disparities in incidence in the top 15 states with highest disparities, especially TX, are needed. Citation Format: Casey Perez, Pankil K. Shah, Aaron Mathews, Edgar Munoz, Alex Bokov, Dharam Kaushik, Joel Michalek, Amelie Ramirez, Ronald Rodriguez, Dimpy P. Shah. Racial disparities in kidney cancer incidence across South Texas, Texas, and United States using TCR, SEER and NPCR registries (2004-2014) [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 4187.
Functional Disorders of the Large Intestine and Their Treatment.
Journal: JAMA (1933)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The bureaucrat. The taming of the DHEW
Authors: M. Martin
Journal: JAMA (1975)

America's dim view of the bureaucrat needs reassessment because professional standards review organizations (PSROs) and national health insurance will increase the amount of contact between physician and bureaucrat. Inevitable conflict between The Organization and the physician is aggravated by the government-business adversary relationship based on constitutionalism. With more public funds, the budget-based health institution may acquire more of the characteristics of bureaucracy. For better understanding, the bureaucrat is described, and his main types and natural history outlined. Contrasts between business and government as revealed by interchange of executives are reported. Remedies for better interaction are suggested, including liaison groups and use of the apolitical, career bureaucrat. Rules for dealing with bureaucracies are listed, including The Constituent's Letter. (<i>JAMA</i>233:976-978, 1975)