tbuckley/cabot-search huggingface dataset:
Participant Index
Authors: Brint Sf, Clark Lm, Aaberg Tm, Arthurb55 Beltranena, Brinton Da, Carrento E 173 Clark, Arthurs B240, Belyea Da, Brockhurst Rj, Carroiigs83 Clarkson Jg, Bustros Sn, Asbell Pa, Brad Rd, Carstens Gj, Clayman Hm, Durfee Da, Ashburn Fs, Bendel Re, Brodell Rt, Cleary Pa, De Juan, Jc Casebeer, Clineschmidt 90, Luise De, Dutton Jj, Ctunie Da, De Potter, Abramson Dh, Atwood Jd, Acosta Dt, Auffarth Gu, Caskey Pj, Cohen Bz86 De Souza, Acquadro Ma, Cassard Sd, Cohen Ej, Deane 65 Eagtejrrc, Adamis Ap, Augsburger Jj, In Aj, Easterbrook 142, Bernstein Hn, Brown Hs, Deitz Cohenms202, Cohensy117 Del, Monte Ma, Avery Rl, Colbyk73 Del, Piero Ej, M219 Brown, Del Lv, Eckstein Mb, Vita-Cora Aguirre, Bellman Sr, J 220 Brown, Cavanaugh Tb, Aylward Gw, Coleman Dj, Detbonoe63 Edelstein, Azar Dt, Bhattacharya Ss, Brown Rh, Cayen Ll220, Deterrne 199, Edmond Jc, Azen Sp69, Bhisitkul R73, Cennamo 132 Colemans, Aiello Lm, Brown Sj, Della Roccs, R 83, Edwards Rp, Aiello Lp, Ainbinder Dj, Bigham Wj, Browning Dj, Deluise Vp, Egan Km52, Ainsworth Jr, Biglan Aw, Brownlow Rl, Chace Collinsjf, Ainsworth Rl, Enerrnan Ra, Aizussdh49 Backlund, Bruninga Hj, Chandler Jw, Condon Gp, Akata Rf, Chandra Sr, Baerveldt 107, Connolly Pj, Desamaulds Ab, Brombal~ El, Bird Ac, Bucci Chang, Connolly Wes, Deschenes Jg, El Sayyad, Akerab228 Baez, Connor Cs, Desmet Md, Ei-Haigw69 Ak~a, Baitnhl59 Birtcm, Buckley Eg, Connor Tb, Deutman Af, Changts82 Contreras, Deutsche Ra, Eldermj65 Alcomdm69, Baker Rs, Blackman Hj, Bullimore Ma, Diamond Jg, Eliason Ja, Alencar Jp, Bakewell Bc, Alexander 241 Balajonda, Aharodv86 Baldritk83, Blankenship Gw, Costa Vp, Dickens Cj, Balyeat Hd, Blanton Cl, J Chased229 Costin, Bansal Rk, Alldredge Oc, Blecher Mh, Allen Aw, Chauhan Bc, Dieckert Jp, Elner Vm, Allen Rc, Barakmh228 Blodi, Busse Bj, Chauvaud 117 Cox, Diggory P71, Elsas Fj, Allen Sd, Blodicf49 Butlercp, Chavez De Ia
Journal: Ophthalmology (1994)
Treatment of Blastomycosis and Histoplasmosis with Ketoconazole
Authors: NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES MYCOSES STUDY GROUP
Journal: Annals of Internal Medicine (1985)

In a multicenter prospective randomized trial, the efficacy and toxicity of low-dose (400 mg/d) and high-dose (800 mg/d) oral ketoconazole were compared in 80 patients with blastomycosis and in 54 with histoplasmosis. Among 65 patients with blastomycosis treated for 6 months or more, high-dose treatment was more effective (100% success rate compared with 79%;p = 0.001). Among 19 patients with chronic cavitary histoplasmosis treated for 6 months or more, both regimens were equally effective (overall success rate, 84%). In 20 patients with localized or disseminated histoplasmosis treated for 6 months or more, low-dose treatment was more effective (100% success rate compared with 57%;p = 0.03). The success rate for all patients with histoplasmosis treated for 6 months or more was 85%. Adverse effects occurred in 81 of 134 patients (60%) and were commoner with the high-dose regimen. Ketoconazole is effective for immunocompetent patients with non-life-threatening, nonmeningeal forms of blastomycosis and histoplasmosis. Because of the higher frequency of side effects associated with the high dose, ketoconazole therapy should be initiated with the low dose.
SAT0132 Severe periodontal disease associated with severe rheumatoid arthritis is a predictive factor for clinical infliximab response
Authors: H. Marotte, P. Miossec, L. Grange, B. Pallot-Prades, P. Gaudin, T. Thomas
Journal: Annals of the Rheumatic Diseases (2013)

<h3>Background</h3> Prediction of TNFα response remains a huge challenge. Recently, a bad dental hygiene was described to be associated with a poor response to TNFα blockers in 20 RA patients. Previously, we reported an association between dental bone loss and joint damage in established 147 RA. <h3>Objectives</h3> Here, we investigated association between severe periodontal disease (PD) with or without joint damage and response to infliximab in RA patients. <h3>Methods</h3> All 101 RA patients enrolled in the study had typical clinical and biological features of severe RA. Their mean (SD) age was 50.6 (15.5) years. Patients were predominantly women (77.2%) with mean disease duration of 12.3 (9.8) years, and 81.2% were RF positive. Most patients had active disease with a DAS28 at 5.1 (1.12) despite methotrexate treatment. They all were treated with infliximab according to the usual regimen in association with methotrexate. ACR 20 response was evaluated at 6 months and DAS28 improvement was calculated. Severe PD was defined by a periodontal bone destruction according to the Hugoson and Jordan criteria by an alveolar bone loss with a horizontal alveolysis over one third of the normal bone height. Joint damage was defined according to the Larsen wrist x ray score with a right Larsen wrist score ≥2. χ<sup>2</sup> test and non-parametric test were performed. <h3>Results</h3> Among our population, 62 patients had severe PD and 73 patients had joint damage. An association between severe PD and joint damage was observed (χ<sup>2</sup> test = 3.9; <i>P</i>&lt;0.05). However, only 48 patients had destruction at both wrist and periondotal sites while 16 had no destruction at these two sites; 23 had only wrist destruction; and 14 had only periodontal destruction. At 6 months, 71 patients reached the ACR20 response criteria. No association between PD severity or joint damage and ACR20 response was observed. Then, we compared DAS28 improvement according to PD severity. Likewise, DAS28 improvement was similar in RA patients with severe PD (median [25th–75th quartile]) at 1.85 [0.59–3.07]) compared to RA patients without severe PD (1.63 [1.01–2.68]; not significant). Similarly, DAS28 improvement was equal according to the joint damage status (1.85 [1.05–3.11]) in RA patients with joint damage compared to RA patients without joint damage (1.53 [0.11–2.79]; not significant). <h3>Conclusions</h3> These results suggested no association between severe periodontal disease and response to infliximab. RA severity markers are not predictor to infliximab response. <h3>Disclosure of Interest</h3> None Declared
VALUE OF STATE BOARD STATISTICS
Journal: JAMA (2011)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Dietary sodium and blood pressure
Authors: F. H. Messerli
Journal: JAMA (1996)

<h3>To the Editor.</h3> —In their meta-analysis of RCTs, Midgley et al<sup>1</sup>found a rather disappointing effect of dietary sodium restriction on blood pressure. Based on these findings, the authors question the wisdom of a sodium restriction in the general population and to a lesser extent in the hypertensive population. However, blood pressure is merely a surrogate endpoint that often, but not always, correlates with the real endpoints, ie, cardiovascular morbidity and mortality. Blood pressure also is an extremely variable measurement that is affected by myriad endogenous and exogenous pathophysiological factors throughout a 24-hour period. A parameter that more consistently reflects the average blood pressure load is LV wall thickness or LV mass. The LV mass has been shown to correlate better with 24-hour blood pressure measurements than with spot measurements and has been clearly identified as a surrogate endpoint for cardiovascular morbidity and mortality, which are far more meaningful than blood pressure
Ultrasound for Juvenile Laryngeal Papillomatosis
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Malathion for treatment of Pediculus humanus var capitis infestation
Authors: D. Taplin
Journal: JAMA (1982)

One hundred fifteen subjects took part in a double-blind study comparing the efficacy and safety of 0.5% malathion lotion (Prioderm lotion) and the alcoholic vehicle of the lotion as pediculicides in the treatment of head lice. The subjects, with a mean age of 9 years, had long-standing lice infestations and at least 20 viable ova. The subjects were treated with the test preparation, which was allowed to remain on the hair for 12 hours. Ovicidal and pediculicidal efficacy for the malathion lotion was significant; overall clinical evaluation by the investigators showed a significant number of moderate to marked therapeutic responses to malathion lotion. Only one adverse reaction (in the malathion lotion group) was reported, the stinging of pyodermal lesions in reaction to the alcoholic vehicle. Other concomitant scalp diseases were unchanged or improved at the end of the study. (<i>JAMA</i>1982;247:3103-3105)
AORTIC MURMUR
Authors: E. L. Moss
Journal: BMJ (1922)

MTirzcRmmIt appears reasonable to suppose that most benefit will bc derived from a vaccine which is as little altered as possible, either by heat or chemical agents.Such a vaccine can be prepared by ether extraction, and I have seen some success with this kind of vaccine.I make no extravagant claims for tlle method, since in my experience all vaccines yield dis- appointing, as well as good, results in apparently similar cases; but it seems to satisfy two of the fundamental require- ments of vaccine therapy-the administration of large non- toxic doses and unaltered bacterial protein.I am aware that this is in opposition to some recent American work, in wllich specific fats are said to be the agents in the production of immunity, but this work needs corroboration before it can be accepted.-Iam, etc.,
Diabetes Mellitus
Authors: Samuel B. Beaser
Journal: New England Journal of Medicine (1958)

IN this report the following aspects of diabetes mellitus are considered: biochemistry and physiology; endocrine effects: anatomy and pathology of the pancreas; insulin and its activity; diagnosis; clinical diabetes and therapy; oral hypoglycemic agents; ketosis; pregnancy and diabetes; and complications.Carbohydrate Metabolism1 For over a decade the use of newer technics has contributed experimentally to the clarification of the biochemical basis for diabetes. At the beginning of this period, the conflicting theories of underutilization and overproduction of sugar had just been reconciled by the acceptance of both as joint participants in the diabetic process. The hope that a single defect . . .
Vaginal prostaglandin E2 and fatal amniotic fluid embolus
Authors: A. Less
Journal: JAMA (1990)

<h3>To the Editor.—</h3> Amniotic fluid embolism is a rare but deadly pathological entity that accounts for roughly 10% of all maternal deaths.<sup>1,2</sup>We describe a fatal outcome following induction of labor with prostaglandin. <h3>Report of a Case.—</h3> A 37-year-old white woman, gravida 4, para 2, aborta 1, was admitted to our labor ward at 42 weeks' gestation for induction of labor. Her current pregnancy was uncomplicated. Results of a genetic amniocentesis at 16 weeks were normal. At 42 weeks, the patient was admitted for an oxytocin challenge test. All vital signs were normal and the cervix was posterior and uneffaced. The results of her oxytocin challenge test were negative and she was discharged after her contractions stopped. The following day, she returned complaining of reduction in fetal movements. The nonstress test was reactive and results of physical examination were unchanged. In an attempt to "ripen" the cervix, 3 mg
Hemobilia
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Loss or Injury of Eye
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Atmospheric Circulation Types and Daily Mortality in Athens, Greece
Authors: Pavlos Kassomenos, Alexandros Gryparis, Evangelia Samoli, Klea Katsouyanni, Spyros Lykoudis, Helena A. Flocas
Journal: Environmental Health Perspectives (2001)

We investigated the short-term effects of synoptic and mesoscale atmospheric circulation types on mortality in Athens, Greece. The synoptic patterns in the lower troposphere were classified in 8 a priori defined categories. The mesoscale weather types were classified into 11 categories, using meteorologic parameters from the Athens area surface monitoring network; the daily number of deaths was available for 1987-1991. We applied generalized additive models (GAM), extending Poisson regression, using a LOESS smoother to control for the confounding effects of seasonal patterns. We adjusted for long-term trends, day of the week, ambient particle concentrations, and additional temperature effects. Both classifications, synoptic and mesoscale, explain the daily variation of mortality to a statistically significant degree. The highest daily mortality was observed on days characterized by southeasterly flow [increase 10%; 95% confidence interval (CI), 6.1-13.9% compared to the high-low pressure system), followed by zonal flow (5.8%; 95% CI, 1.8-10%). The high-low pressure system and the northwesterly flow are associated with the lowest mortality. The seasonal patterns are consistent with the annual pattern. For mesoscale categories, in the cold period the highest mortality is observed during days characterized by the easterly flow category (increase 9.4%; 95% CI, 1.0-18.5% compared to flow without the main component). In the warm period, the highest mortality occurs during the strong southerly flow category (8.5% increase; 95% CI, 2.0-15.4% compared again to flow without the main component). Adjusting for ambient particle levels leaves the estimated associations unchanged for the synoptic categories and slightly increases the effects of mesoscale categories. In conclusion, synoptic and mesoscale weather classification is a useful tool for studying the weather-health associations in a warm Mediterranean climate situation.
Coloured Funnel
Authors: M. Therese Southgate
Journal: JAMA (2002)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Analgesic Nephropathy
Authors: Marc E. De Broe, Monique M. Elseviers
Journal: New England Journal of Medicine (1998)

Classic analgesic nephropathy is a slowly progressive disease resulting from the daily use for many years of mixtures containing at least two antipyretic analgesics and usually caffeine or codeine (or both), which may lead to psychological dependence. The nephropathy is characterized by renal papillary necrosis and chronic interstitial nephritis, with an insidious progression to renal failure, sometimes in association with transitional-cell carcinoma of the uroepithelium.14 In the early stages of the disease, the clinical symptoms are limited to polyuria, sometimes associated with sterile pyuria, and renal colic that is occasionally associated with acute renal failure due to bilateral obstruction . . .
Research Fraud
Journal: JAMA (2006)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Excitatory Amino Acid Receptors: Their Classes, Pharmacology, And Distinct Properties In The Function Of The Central Nervous System
Authors: D. Monaghan
Journal: The Annual Review of Pharmacology and Toxicology (1989)

Due to the massive data sets available for drug candidates, modern drug discovery has advanced to the big data era. Central to this shift is the development of artificial intelligence approaches to implementing innovative modeling based on the dynamic, ...Read More
The Romance of Exploration and Emergency First-Aid from Stanley to Byrd
Journal: JAMA (1935)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal