tbuckley/cabot-search huggingface dataset:
Some sand for the tracks
Authors: W. W. Hall
Journal: JAMA (1972)

Our main business is not to<i>see</i>what lies dimly at a distance, but to<i>do</i>what lies clearly at hand. Thus spoke the Seventh Earl of Carlisle over a century ago. Two years ago you, the members of this House of Delegates, chose me to serve as your President-Elect. One year ago I was installed as your President. This is one of the greatest honors that can be conferred upon a physician. An honor—Yes! But you gave me a<i>job</i>to do—to help represent the medical profession to emphasize across the width and breadth of this land that our profession is one of<i>service</i>to our patients and the American public, a magnificent profession. During the past two years I have attempted to visit with every doctor possible at every medical meeting I have attended. Every meeting has been a pleasant experience and very rewarding. Of all the
High prevalence of HTLV‐I infection among the family members of a patient with adult T‐cell leukemia/lymphoma from northeastern Japan
Authors: Kazuyuki Shimizu
Journal: American Journal of Hematology (1999)

Human T-cell lymphotropic virus type I (HTLV-I) is transmitted through infected lymphocytes mostly by breast feeding. In the present study, high prevalence of HTLV-I infection was disclosed in the family members of a patient with adult T-cell leukemia/lymphoma (ATL), all of whom were residents of Iwate, northeastern Japan. Long-term follow-up is necessary for people with HTLV-I infection because of the risk of developing ATL after a certain period of latency. New inventive treatments for the acute and lymphomatous types of ATL are needed. Am. J. Hematol. 61:78–81, 1999. © 1999 Wiley-Liss, Inc.
Autoimmune Diseases
Journal: JAMA (2001)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Evaluation of Lithium Carbonate for Treatment of Manic-Depressive Psychosis
Journal: JAMA (1971)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
ADA News and Meetings
Authors: Gregory Alvarez, Jean-Luc Ardilouze, Samuel Arthur, Lori Barnette, Joseph Barrera, Diane Barry, Wendy Bartanen, Sandra Bell, Judy Beriou, M Lance, Douglas Berry, Karl Bloomquist, James Bowman, Lawerence Breaox, La Britt Brockman, Steven Brownstein, Betsy Butler, Thomas Calabrese, Belinda Caster, Celia Darland, San Antonio, Ruth Darlington, Umesh Dashora, Ajay Dashottar, Sherry David, Larry Decook, Helen Derrick, Albert Dinicola, Laguna Niguel, Mitchell Dorris, Kathleen Dummitt, Guam Elliott, Katherine Eyres, British Columbia, Francesco Canada, Mary Francisco, Bernier Finnie, Catherine Ginette, David Giobus, Gwyn Gough, Thomas Gould, Mark Haferman, Roger Hall, Marie Hanley, Karyl Hare, Phyllis Harris, Cathleen Hauschildt, Matthias Hediger, Kevin Holton, Jerry Houtart, S Petersburg, George Huck, Sherma Jack-Brisseau, Jan Juchniewicz, Robert Katz, Corinne Kauderer, Johnette Ke1ser, P Altoona, Patrick King, Richard Kunigsberg, Lee Laney, Robyn Luther, Cheryl Magner, Inger Magnusson, William Mahanna, Lorraine Mammone, Lawrence Mandel, Merville Marshall, Mohamed Osman Mekkl, Arabia Stasia, Louise Miaskiewicz, Lorena Mlklavcic, Andrew Montgomery, Robert Moss, Jeanne Mott, Los Angeles, Kimbery Murphy, Allison Park, John Nicholson, Armiva Olson, Juleen Paul, Thomas Persons, Cherryl Ranger, Mark Ritzinger, Marry Robinson, Huntington Beach, James Rothman, Julie Sabo, Lynn Sadowsky-Holcomb, Mark Schleichert, Menlo Schmitt, Dennis Park, Nancy Schwartz, David Scofield, Andrew Denver, Melissa Shapiro, David Sloan-Epidendio, Ira Small, Helen Stein, Bill Suggs, S Tanner, Paulette Louis, Emerald Brea, San Thomas, Constance Antonio, Judith Thompson, Sharon Tiller, Robert Tollin, Jesus Turner, Kay Villarreal, Michael Waxman, James Webb, Ok Williams, Dennis Woodung
Journal: Diabetes Care (1992)
E PLURIBUS UNUM
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Reproductive Immunology
Authors: Richard H. Nalick
Journal: JAMA (1982)

As eloquently stated by Dr Saul R. Gusberg in the foreword to<i>Reproductive Immunology</i>, "this volume represents a milestone, for it will establish the identity of reproductive immunology as a significant area of basic immunology and as a significant division of the discipline of reproductive medicine." Initially a subdivision of bacteriology, and further developed coincident with the emergence of molecular biology, the science of immunology has now influenced almost all areas of medicine. With the growth of obstetrics and gynecology, both as a clinical and basic science, areas of subspecialization have recently become firmly established and have grown both as to their utility in clinical medicine and in the complexity of their respective subject matter. All three major areas, gynecologic oncology, endocrinology-infertility, and maternal-fetal medicine, have been enhanced by the application of immunologic principles and concepts. Thus, important advances in gynecologic tumor immunology have made the potential of early diagnosis
Acute or chronic respiratory failure. Assessment and management of patients with COPD in the emergency setting
Authors: G A Schmidt, J B Hall
Journal: JAMA (1989)

Patients with acute on chronic respiratory failure exhibit severe pulmonary impairment as a baseline characteristic. Additional minor insults can precipitate cardiopulmonary failure that requires hospital admission and possibly mechanical ventilation. Our approach to these patients emphasizes evaluation of the imbalance between neuromuscular competence and mechanical load on the respiratory system. In this way, reversible factors can be identified and corrected before they progress to inspiratory muscle fatigue and respiratory failure. For cases in which deterioration is inexorable, guidelines for mechanical ventilation are given and approaches to eventual liberation from the ventilator are reviewed. (<i>JAMA</i>. 1989;261:3444-3453)
Genetics and laws prohibiting marriage in the United States
Authors: M. G. Farrow
Journal: JAMA (1969)

Laws prohibiting marriage in the 50 states, the District of Columbia, and two territories have been classified as those inclusive for categories of lineal and collateral relatives, and those specific for lineal, collateral, and affinous relatives. A person may not marry a parent, grandparent, child, or grandchild except in Georgia, where a man is not prohibited from marrying his daughter or grandmother. While all political units prohibit marriage between a person and a sibling, an aunt, or an uncle, their prohibitions vary considerably for other degrees of collateral relationship. The uncle-niece marriage is not prohibited in Georgia and among Jews in Rhode Island. Generally, marriage between persons with a coefficient of relatedness equivalent to first cousins or closer has been prohibited. Fewer than one half of the political divisions have prohibitions regarding affinous relatives.
CONGENITAL NYSTAGMUS
Authors: T. S. Evans
Journal: BMJ (1925)

I,f ATTfA 4D1CAL JOURwAr.from Februarv 15th to 29th.Infected mosquitos were fed on February 20th, and thus 60 grains were given before the infection and 90 grains after.No pyrexia followed, but the blood showed scanty parasites from March 14th for a few days, thereafter becoming negative.On April 23rd parasites again found.From April 23rd to 25th quinine sulphate, 30 grains daily, was given.On May 24th an intramuscular injection of 2 c.cm. of infectedblood was given, but no iinfection followed, the blood remaining negative.
Medical Humanists of the Renaissance
Journal: JAMA (1987)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Interchangeability of conjugated Haemophilus influenzae type b vaccines in infants
Authors: E. L. Anderson
Journal: JAMA (1995)

<h3>Objective.</h3> —To evaluate the safety and immunogenicity of two<i>Haemophilus influenzae</i>type b (Hib) conjugate vaccines when administered in serial combination. These vaccines consisted of Hib capsular polysaccharide polyribosyl-ribitol phosphate (PRP) conjugated to the meningococcal outer membrane protein (OMP) complex (PRP-OMP) and<i>H influenzae</i>oligosaccharide conjugated to a mutant toxin (CRM197) isolated from<i>Corynebacterium diphtheriae</i>(HbOC). <h3>Design.</h3> —Randomized, double-blind, clinical trial evaluating five Hib vaccination regimens. <h3>Setting.</h3> —Vaccine Treatment and Evaluation Units and affiliated private pediatric practices at Saint Louis (Mo) University, Vanderbilt University, Nashville, Tenn, and Baylor College of Medicine, Houston, Tex. <h3>Patients.</h3> —A total of 497 healthy 2-month-old infants scheduled to receive routine immunization. <h3>Intervention.</h3> —Participants received either PRP-OMP or HbOC given as recommended by the manufacturer, PRP-OMP at 2 and 6 months, HbOC at 2 months, then PRP-OMP at 4 and 6 months, or PRP-OMP at 2 months and then HbOC at 4 and 6 months. Unconjugated PRP was given at 15 months to evaluate priming. <h3>Results.</h3> —Geometric mean antibody concentrations differed significantly among the groups following the second and third immunizations of the primary series and following booster immunization with unconjugated PRP. On each occasion, the groups receiving serial combinations of PRP-OMP and HbOC achieved mean antibody concentrations that equalled or exceeded those of the groups receiving a single product. Adverse reactions did not vary by group. <h3>Conclusions.</h3> —The studied sequential combinations of Hib vaccines were safe and at least as immunogenic as either vaccine alone. (<i>JAMA</i>. 1995;273:849-853)
Linezolid: The First Oxazolidinone Antimicrobial
Authors: Robert C. Moellering
Journal: Annals of Internal Medicine (2003)

Letters18 November 2003Linezolid: The First Oxazolidinone AntimicrobialRobert C. Moellering Jr., MDRobert C. Moellering Jr., MDFrom Harvard Medical School; Beth Israel Deaconess Medical Center.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-139-10-200311180-00018 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:Dr. Johnson is correct in his comments about TMP-SMX as a potential therapeutic agent for MRSA infections. As he points out, however, because the drug is no longer subject to patent protection, it is highly unlikely that a large-scale comparative study of this agent will be undertaken for MRSA infections. In this context, unlike the recently described vancomycin-resistant MRSA (which thus far is very rare), the strains that are resistant to TMP-SMX do occur and, of course, would not be expected to respond to that agent.Dr. Lindley is also correct: The oral formulation of linezolid is very ... Author, Article, and Disclosure InformationAuthors: Robert C. MoelleringJr., MDAffiliations: From Harvard Medical School; Beth Israel Deaconess Medical Center. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoLinezolid: The First Oxazolidinone Antimicrobial Robert C. Moellering Jr. Linezolid: The First Oxazolidinone Antimicrobial James R. Johnson Linezolid: The First Oxazolidinone Antimicrobial D. A. Lindley Linezolid: The First Oxazolidinone Antimicrobial David L. Paterson , A. William Pasculle , and Kenneth McCurry Metrics Cited byScreening approaches and therapeutic targets: The two driving wheels of tuberculosis drug discoveryCurrent advances in the clinical development of anti-tubercular agentsSynthesis of Chiral N-Nitro-oxazolidin-2-ones and O-(β-Nitraminoalkyl) Carbamates in Liquefied 1,1,1,2-Tetrafluoroethane MediumMicrobial Natural Products in Drug Discovery 18 November 2003Volume 139, Issue 10Page: 864KeywordsAntibioticsAntimicrobialsDrug therapyDrugsHospitalizationsMethicillin-resistant staphylococcus aureusOutpatientsVancomycin ePublished: 18 November 2003 Issue Published: 18 November 2003 Copyright & PermissionsCopyright © 2003 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Choline deficiency: A cause of hepatic steatosis during parenteral nutrition that can be reversed with intravenous choline supplementation*1, *2
Authors: A BUCHMAN
Journal: Hepatology (1995)

Patients receiving long-term total parenteral nutrition (TPN) develop hepatic steatosis as a complication. Our previous studies have shown this to be caused, at least in part, by choline deficiency. We studied four patients (1 man, 3 women) aged 50 ± 13 years who had low plasma-free choline concentrations 4.8 ± 1.7 (normal, 11.4 ± 3.7 nmol/mL). The patients had received TPN for 9.7 ± 4.7 years. They received parenteral nutrition solutions containing choline chloride (1 to 4 g/d) for 6 weeks. Abdominal computed tomography (CT) was performed at baseline, biweekly during the choline supplementation, and 4 weeks after discontinuation of choline. During choline administration, the plasma-free choline concentration increased into the normal range within 1 week in all four patients and remained at or above the normal range for all 6 weeks, but decreased back to baseline when choline supplementation was discontinued. Hepatic steatosis resolved completely, as estimated by CT. Liver density increased from −14.2 ± 22.3 Hounsfield units (HU) to 8.4 ± 10.3 HU at week 2 (P = .002); 9.6 ± 10.7 HU at week 4 and 13.1 ± 7.3 HU at week 6, as determined by the liver-spleen CT number difference obtained by the subtraction of the average spleen CT number (in HU) from the average liver CT number. This improvement continued up to 4 weeks after choline supplementation (13.8 ± 2.8 HU). Hepatic steatosis was shown to have recurred in one patient after 10 weeks of return to choline-free parenteral nutrition. The hepatic steatosis associated with parenteral nutrition can be ameliorated, and possibly prevented, with choline supplementation. Therefore, choline may be an essential nutrient for patients who require long-term parenteral nutrition.
"Epidemic Collapse"
Authors: A. Frame
Journal: BMJ (1965)

catheter and the connecting tube had then been strapped to the abdominal wall with Elastoplast strapping.Two weeks later the patient made a complete recovery from renal failure with no significant abdominal symptoms, and at laparotomy the catheter was found to be lying free in the peri- toneum very close to its initial point of insertion.It had excited no peritoneal reaction at all.We had thought that our method of fixing the catheter (with purse-string suture and two separate pieces of plaster) was perfectly safe, but this is clearly not the case.Now we fit a small cuff of rubber pressure tubing (3 mm.x 5 mm.-FranklinsLtd.) over the catheter once the latter has been inserted and fixed with a purse-string suture.This cuff fits very firmly and can be pushed down until it is close to the abdominal wall, and the catheter can then be strapped in the usual way.We consider that this provides an adequate safeguard against a similar occurrence.A further precaution would be the inclusion of a radio-opaque marker in the catheter, which is at present completely radio-translucent.In this patient's case we could not be absolutely certain before operation that the catheter was in the abdomen.-Weare, etc.,
Statistical issues in risk assessment of reproductive outcomes with chemical mixtures.
Authors: V S Hertzberg, G K Lemasters, K Hansen, H M Zenick
Journal: Environmental Health Perspectives (1991)

Establishing the relationship between a given chemical exposure and human reproductive health risk is complicated by exposures or other concomitant factors that may vary from pregnancy to pregnancy. Moreover, when exposures are to complex mixtures of chemicals, varying with time in number of components, doses of individual components, and constancy of exposure, the picture becomes even more complicated. A pilot study of risk of adverse reproductive outcomes among male wastewater treatment workers and their wives is described here. The wives of 231 workers were interviewed to evaluate retrospectively the outcomes of spontaneous early fetal loss and infertility. In addition, 87 workers participated in a cross-sectional evaluation of sperm/semen parameters. Due to the ever-changing nature of the exposure and the lack of quantification of specific exposures, six dichotomous variables were used for each specific job description to give a surrogate measure of exposure. Hence, no quantitative exposure-response relationships could be modeled. These six variables were independently assigned by two environmental hygienists, and their interrater reliability was assessed. Results are presented and further innovations in statistical methodology are proposed for further applications.
T-Cell Defect in Diffuse Large B-Cell Lymphomas Involves Expansion of Myeloid Derived Suppressor Cells Expressing IL-10, PD-L1, and S100A12
Authors: Imane Azzaoui, Fabrice Uhel, Delphine Rossille, Céline Pangault, Joelle Dulong, Jerome Le Priol, Thierry Lamy, Roch Houot, Steven Le Gouill, Guillaume Cartron, Pascal Godmer, Krimo Bouabdallah, Noel Milpied, Karin Tarte, Thierry Fest, Mikael Roussel
Journal: Blood (2015)
Post-Graduate Lectures on Orthopedic Diagnosis and Indications. Volume III, Section A: Tuberculosis of the Skeletal System. Section B: Osteomyelitis
Journal: JAMA (1952)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
L-Asparaginase
Authors: John P. Whitecar, Gerald P. Bodey, Jules E. Harris, Emil J. Freireich
Journal: New England Journal of Medicine (1970)

L-ASPARAGINASE affords a unique approach to the chemotherapy of malignant neoplasms by exploiting a metabolic difference between tumor cells and host cells.Historical BackgroundIn 1953 Kidd1 noted that normal guinea-pig serum has antitumor activity, and Broome2 subsequently showed that the active antitumor substance is L-asparaginase, which is present in high concentration in the serum of the guinea pig and its close relatives. Dolowy and his associates3 used purified guinea-pig serum to treat a boy with acute lymphoblastic leukemia and obtained an objective response. The discovery of Escherichia coli L-asparaginase with antitumor activity presented a source of enzyme in sufficient . . .