tbuckley/cabot-search huggingface dataset:
Ensuring autopsy lives on
Authors: None The Lancet
Journal: The Lancet (2007)

Autopsy is a highly sensitive issue in the UK, following the organ-retention affair at Alder Hey Children's Hospital, Liverpool, UK, in the late 1990s, in which organs and tissues from infants who died at the hospital were kept for study without consent. The public concern and regulation that followed this troubling case are likely to have contributed to the subsequent drop in hospital autopsy rates in the UK. But as Julian Burton and James Underwood highlight in their Review in today's Lancet, autopsy rates were in decline before Alder Hey and not only in the UK.
THE QUESTION OF CRUELTY IN THERAPEUTIC OBSERVATIONS.
Journal: JAMA (1900)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
From the Alcohol, Drug Abuse, and Mental Health Administration
Authors: F. K. Goodwin
Journal: JAMA (1989)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Emotional Stress and Heart Disease
Journal: JAMA (1971)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Amino acids in liver disease: a cause of hepatic encephalopathy?
Authors: A. L. Baker
Journal: JAMA (1979)

Patients with chronic liver disease often have elevations in plasma levels of aromatic amino acids, including tyrosine, phenylalanine, and tryptophan, as well as methionine, glutamate, aspartate, and ornithine; branched-chain amino acids, leucine, isoleucine, and valine, are usually depressed.<sup>1,2</sup>Fischer et al<sup>3</sup>have focused the interest of clinicians and investigators alike on the pathogenesis and treatment of hepatic encephalopathy by suggesting that the depressed ratio of branched-chain to aromatic amino acids may have etiologic importance in hepatic coma.<sup>4</sup>A corollary of this hypothesis is that restoration of this ratio to normal should not only provide specific treatment for hepatic encephalopathy but should also allow administration of enough protein equivalents of amino acids to attain nitrogen balance without precipitating hepatic coma. Nutritional repletion may also prevent further deterioration of hepatic structure and function. A recent dietary survey reported substantially less protein consumption in patients with alcoholic hepatitis and cirrhosis
Literature and Medicine: Contributions to Clinical Practice
Authors: Rita Charon
Journal: Annals of Internal Medicine (1995)

Letters15 December 1995Literature and Medicine: Contributions to Clinical PracticeRita Charon, MD, Julia E. Connelly, MD, and Anne Hunsaker Hawkins, PhDRita Charon, MDCollege of Physicians and Surgeons of Columbia University New York, NY 10032University of Virginia School of Medicine Charlottesville, VA 22908The Pennsylvania State University College of Medicine Hershey, PA 17033, Julia E. Connelly, MDCollege of Physicians and Surgeons of Columbia University New York, NY 10032University of Virginia School of Medicine Charlottesville, VA 22908The Pennsylvania State University College of Medicine Hershey, PA 17033, and Anne Hunsaker Hawkins, PhDCollege of Physicians and Surgeons of Columbia University New York, NY 10032University of Virginia School of Medicine Charlottesville, VA 22908The Pennsylvania State University College of Medicine Hershey, PA 17033Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-123-12-199512150-00029 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:We thank Dr. Horton for expanding the medical applicability of literary methods to include the interpretation of clinical research. In the act of writing, the author assumes a narrative contract with the reader that, if all goes well, leads to some change in the reader—edification, comfort, or a change in understanding. Rhetorical analyses can help us to achieve the critical skill required to evaluate research, thus clarifying the researchers' intentions, interpretations, and biases. In addition to defining generalizability, other projects within clinical research rest, in part, on interpretive functions; for example, deciding on statistical methods, clarifying the meaning ... Author, Article, and Disclosure InformationAffiliations: College of Physicians and Surgeons of Columbia University New York, NY 10032University of Virginia School of Medicine Charlottesville, VA 22908The Pennsylvania State University College of Medicine Hershey, PA 17033 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByBibliographie 15 December 1995Volume 123, Issue 12Page: 966KeywordsChartsMotivationStatistical dataStatistical methods Issue Published: 15 December 1995 CopyrightCopyright © 1995 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...
Ashes, Ashes
Authors: Steward Massad
Journal: JAMA (1995)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Peripheral Vascular Diseases
Authors: Charles V. Menendez, Robert R. Linton
Journal: New England Journal of Medicine (1954)

Diseases of Veins and LymphaticsVaricose VeinsMany forms of mechanical obstruction and anatomic abnormalities have been blamed for simple varicose veins, but these factors have never been established as definite etiologic agents.171 , 172 Heredity, it appears, plays the most important part, though a hormonal mechanism may also be involved during pregnancy. The symptomatology includes tiredness and heaviness of the legs, swelling, poor cosmetic appearance and ulceration. Even dyspnea, dizziness and precordial distress have been reported from pooling of blood in varicose veins.169 It is possible frequently to outline the main and accessory venous trunks and also to determine the site . . .
Circumcision and urinary tract infection
Authors: W. F. Rosenberger
Journal: JAMA (1992)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Pulmonary rehabilitation
Authors: R Jones
Journal: Thorax (2002)

<b>Background:</b> Early intervention used in the intensive care unit, through neuromuscular electrical stimulation (NMES), presents benefit to critically ill patients, minimizing the deleterious effects of long-term immobilization. <b>Objectives:</b> To assess an NMES protocol with the conventional treatment for peripheral muscles through of the peak torque evoked analysis quadriceps femoris in critically ill patients with traumatic brain injury (TBI). <b>Method:</b> Experimental study, double-blind, held at the Base Hospital of the Federal District. Fifty-six critically ill patients with TBI admitted to the intensive care unit (ICU) were randomized to the NMES group (which received daily sessions of NMES) and the control group (conventional treatment). Muscle strength was measured by PT evoked by NMES through load ballot coupled to table adapted from Bonnet. <b>Results:</b> Twenty-four patients were considered for analysis NMES group (n = 10) (age 32 ± 8.9) and control group (n = 14) (age 32.5 ± 9.6). Regarding the PT evoked by NMES, the absolute average values were 22.2 ± 7.1 KgF for the intervention group and 14 ± 7.2 KgF for the control group, p &lt; 0.001. <b>Conclusion:</b> The daily sessions of ENEM applied for 50 minutes, from the first day of hospitalization in patients with TBI was able to provide a decrease in the loss of peripheral muscle strength of quadriceps.
Verapamil prophylaxis of migraine. A double-blind, placebo-controlled study
Authors: G. D. Solomon
Journal: JAMA (1983)

We undertook a double-blind, placebo-controlled study to determine the effectiveness of verapamil hydrochloride for the prophylaxis of migraine. Twelve patients were given either verapamil hydrochloride, 80 mg four times daily, or placebo in random order during two consecutive three-month periods. Migraine frequency, severity, and duration were quantified by daily logs and monthly questionnaires. Ten of the 12 patients had fewer migraines during verapamil therapy. Migraine frequency decreased from 6.7 to 3.8 migraines per patient per month, for a mean decrease of 49%. Headache unit index fell from an average of 0.61 to 0.44. We conclude that verapamil is effective in the prophylaxis of migraine and that verapamil might be considered one alternative in the development of a regimen for the prophylaxis of migraine. (<i>JAMA</i>1983;250:2500-2502)
Correction to: N-Myc promotes therapeutic resistance development of neuroendocrine prostate cancer by differentially regulating miR-421/ ATM pathway
Authors: Yu Yin, Lingfan Xu, Yan Chang, Tao Zeng, Xufeng Chen, Aifen Wang, Jeff Groth, Wen-Chi Foo, Chaozhao Liang, Hailiang Hu, Jiaoti Huang
Journal: Molecular Cancer (2019)

Following publication of the original article [1], the authors reported that name that appeared in published online version is incorrect. Aifeng Wang should be Aifen Wang. Corrected name is provided in the author group section above.
Histological primary biliary cholangitis changes in patients with positive serology and normal alkaline phosphatase
Authors: Silvia Costantini, Andreas Cerny, Guido Stirnimann, Magdalena Filipowicz Sinnreich, Joachim C. Mertens, David Semela, Adriana Baserga, Stefano Bellentani, Elisabetta Merlo, Giorgina Mieli-Vergani, Diego Vergani, Benedetta Terziroli
Journal: Journal of Hepatology (2020)
Staphylococcus Antigen Protects Mice
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Infection and pheochromocytoma
Authors: M. G. Myers
Journal: JAMA (1977)

A urinary tract infection with possible septicemia and endocarditis developed in a 36-year-old man. The illness was complicated by pulmonary embolism, thrombocytopenia, hematemesis, hepatic dysfunction, paralytic ileus, and accelerated hypertension. The latter finding suggested pheochromocytoma. Treatment with antibiotics and phenoxybenzamine hydrochloride was associated with notable clinical improvement. A chromaffin cell tumor was surgically removed above the left kidney. Conclusively, a pheochromocytoma may mimic and be present in association with infection. (<i>JAMA</i>237:2095-2096, 1977)
THE NEW PRESIDENT OF THE ASSOCIATION.
Journal: JAMA (1902)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
PREDICTIVE VALUE OF ENDOSCOPIC ESOPHAGEAL ABNORMALITIES FOR RESIDUAL ESOPHAGEAL CANCER AFTER NEOADJUVANT CHEMORADIOTHERAPY
Authors: RD van der Bogt, BJ van der Wilk, S Nikkessen, KK Krishnadath, EJ Schoon, LE Oostenbrug, PD Siersema, FP Vleggaar, JJB van Lanschot, MCW Spaander
Journal: Endoscopy (2020)

Aims Endoscopic evaluation of the esophageal mucosa may play a role in an active surveillance strategy after neoadjuvant chemoradiotherapy (nCRT) for esophageal cancer. This study aimed to investigate the yield of endoscopic abnormalities of the esophageal mucosa for detection of residual disease (RD).
Do IIb/IIIa receptor blockers improve in-hospital outcomes in patients undergoing rescue percutaneous coronary interventions? Julian M. Esteban, Eric R. Bates, David Share, Michael J. O'Donnell, Kim A. Eagle, Anthony DeFranco, Eva Kline-Rogers, Vivian Clark, Ann Maxwell-Eward, Mauro Moscucci, For the Blue Cross Blue Shield of Michigan Cardiovascular Consortium (BMC2). University of Michigan, Ann Arbor, MI
Journal: Journal of the American College of Cardiology (2001)
Ectopic Gestation
Authors: C. Uhma
Journal: BMJ (1949)

<h3>Introduction</h3> Medical treatment is a less invasive alternative to surgical management of missed miscarriage. Studies have shown that pretreatment with mifepristone can increase the complete abortion rate in management of first-trimester missed miscarriage compared with misoprostol alone. Two studies have also shown that pretreatment with letrozole could increase the efficacy compared with misoprostol alone. So far, there is no trial comparing letrozole and mifepristone pretreatment for missed miscarriage. We designed this randomised controlled trial to test the hypothesis that for first-trimester missed miscarriage, letrozole pretreatment is non-inferior to mifepristone pretreatment followed by misoprostol in terms of complete abortion rate. <h3>Methods and analysis</h3> This is a prospective open-label non-inferiority randomised controlled trial conducted in a single centre. In total, 294 women diagnosed with first-trimester missed miscarriage opting for medical treatment is recruited with informed consent. They are randomly assigned to receive mifepristone or letrozole pretreatment. In the mifepristone group, each woman takes 200 mg mifepristone orally followed 24–48 hours later by 800 µg misoprostol vaginally. In the letrozole group, each woman takes 10 mg letrozole orally per day for 3 days, followed by 800 µg misoprostol vaginally on the third day of letrozole administration. Follow-up is conducted on days 15 and 42 after misoprostol administration. The primary outcome is the overall complete abortion rate. Secondary outcomes include side effects and complications during the study period. Data will be analysed with both intention-to-treat and per protocol approaches. A p&lt;0.05 will be considered as indicating statistical significance. <h3>Ethics and dissemination</h3> Ethics approval has been obtained from the Institutional Review Board of the University of Hong Kong-Shenzhen Hospital with approval number: (2020)166. Findings will be disseminated in a peer-reviewed journal and in national and/or international meetings to guide future practice. <h3>Trial registration number</h3> ChiCTR2000041480.
Ultrasound treatment relieves pain in carpal tunnel syndrome
Journal: BMJ (1998)

Ultrasound treatment relieves pain in carpal tunnel syndromeNo effective conservative treatment exists for carpal tunnel syndrome, and surgical decompression is often performed.In a randomised, "sham" controlled study of an intensive schedule of 20 sessions of ultrasound treatment, Ebenbichler et al (p 731) found that treatment led to short and medium term relief of pain and neurological symptoms in patients with mild to moderate forms of the syndrome.Optimal schedules of ultrasound treatment used alone or in combination with other medical treatments await elucidation.Long term efficacy is yet to be determined.
Association News
Authors: F. Trendelenburg
Journal: JAMA (1906)

<h3>Minutes of Section on Diseases of Children.</h3> In the official minutes of the sections published inThe Journal, July 7, the proceedings of the Section on Diseases of Children, Friday morning, June 8, were omitted. They are as follows: <h3>Friday, June 8—Morning.</h3> Dr. E. T. Shelley, Atchison, Kan., read a paper on "Superstition in Teratology." The paper was discussed by Drs. D. S. Hanson, Cleveland; George N. Acker, Washington; William T. Watson, Baltimore; G. W. Baker, Ogden, Utah; J. B. Learned, Northampton. Mass.; J. L. Morse, Boston; L. F. Bishop, New York; B. B. Simms, Talladega, Ala.; J. L. Morse. Boston, and E. T. Shelley. Dr. Samuel Amberg, Baltimore, read a paper on "The Opsonic Content of the Blood of Infants." Dr. Louis Faugères Bishop read a paper entitled "Constitutional Low Arterial Tension in Children." The paper was discussed by Drs. Arthur W. Fairbanks, Boston, Samuel M. Hamill, and L.