tbuckley/cabot-search huggingface dataset:
Role of Victims' Services in Improving Intimate Partner Violence Screening by Trained Maternal and Child Health-Care Providers—Boston, Massachusetts, 1994-1995
Journal: JAMA (2000)

From 1992 to 1996, approximately 1 million incidents of nonfatal intimate partner violence (IPV) occurred each year in the United States; 85% of victims were women. In 1989, pediatric research found a concurrence of victimization of mothers and their children and supported a recommendation that maternal and child health-care providers (HCPs) pursue training and advocate for increased access to services to promote the safety and well-being of mothers and their children. From 1992 to 1997, the Pediatric Family Violence Awareness Project (PFVAP), a training project for maternal and child HCPs, promoted prevention of and intervention for IPV in Massachusetts. In 1994, PFVAP conducted a pilot evaluation in two urban community health centers to determine whether HCPs trained to conduct IPV assessment would increase their screening rates of women at risk for IPV if an on-site referral service for victims was available. This report summarizes the results of the pilot project, which indicate that IPV screening rates did not increase after implementing on-site victim service.
Essentials of Chemistry and Toxicology.
Journal: JAMA (1894)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Longterm follow-up of 364 patients treated with interferon ?-2A for chronic hepatitis C: Role of genotype and viremia , Roche Molecular Systems, Somerville NJ and Royal Brisbane Hospital, Australia
Journal: Hepatology (1995)

Background. Interferon α with ribavirin combination therapy is effective but still unsatisfactory in the treatment of patients with interferon-relapsed chronic hepatitis C.Aims. To compare, in a randomized, double blind, placebo-controlled study, high-dose interferon-α2b with or without ribavirin in the treatment for interferon-relapsers.Patients. A total of 52 patients with interferon-relapsed chronic hepatitis C were randomly assigned to receive 24-week treatment with interferon-α2b (6 MU three times per week) combined with either ribavirin (1, 000 to 1,200 mg per day) or a matched placebo and then followed for an additional 24 weeks.Methods. Hepatitis C virus RNA was detected by reverse-transcription polymerase chain reaction. For determining viral concentration, the commercial bDNA Quantiplex hepatitis C virus-RNA 2.0 assay was used. Genotyping was performed by reverse hybridization assay.Results. At the end of treatment, no detectable hepatitis C virus RNA levels were observed in 92% (2426) of patients on interferon α2b/ribavirin and 81 % (2126) of patients on interferon α2b/place-bo. At the end of the follow-up, a higher sustained virological response rate was seen in patients treated with interferon α2b/ribavirin than those treated with interferon α2b/placebo (69% vs 23%, p<0.001). Patients with either initially high levels of viral concentration or with genotype 1 responded poorly. Patients who received interferon-α2b/ribavirin treatment and in whom no hepatitis C virus RNA was detected at 4th week after treatment had 90% chance to achieve sustained virological response.Conclusions. High-dose interferon-α2b plus ribavirin treatment is highly effective in interferon-relapsed patients.
Secular Trends and Dynamics of Hospital Associated Methicillin-Resistant<i>Staphylococcus aureus</i>
Authors: Laurence ARMAND-LEFEVRE, Cagri BUKE, Etienne RUPPE, FranÃ§ois BARBIER, Isabelle LOLOM, Antoine ANDREMONT, Raymond RUIMY, Jean-Christophe LUCET
Journal: Clinical Microbiology and Infection (2009)
Lesinurad/Allopurinol (Duzallo) for Gout-Associated Hyperuricemia
Journal: JAMA (2018)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Weight gain after cessation of smoking
Authors: J. E. Lincoln
Journal: JAMA (1969)

<h3>To the Editor:—</h3> It was a pleasure to see George Berkeley quoted in Dr. L. I. Gardner's letter, (<b>209</b>:1528, 1969) because some of Berkeley's ideas are still relevant. Turbayne has pointed out that Berkeley's theory of vision was much more than that. It was also a metaphor for explaining how we exist in the world.<sup>1</sup>In contrast to Cartesian mechanism, Berkeley clearly regarded natural phenomena as a language or discourse to be studied and interpreted. For him, what Dr. Gardner called a "more sophisticated<i>perception</i>of the world" would be a more sophisticated<i>interpretation</i>because the world existed as a visual language needing interpretation rather than as a picture to be perceived. Sense data act as "signs by means whereof things not actually perceived by sense are signified or suggested to the imagination which alone perceives them. All signs suggest the things signified. A great number of arbitrary signs,
OVERSUPPLY OF MEDICAL GRADUATES.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Barium Swallow
Authors: Roscoe E. Miller
Journal: JAMA (1966)

<h3>To the Editor:—</h3> The term "barium swallow" used to request a radiological examination is usually a disservice to the clinician, the patient, and the consulting radiologist. Unfortunately, this term is so ingrained in some physicians that it is probably ineradicable. However, the practitioner usually will obtain far more precise information, and will need fewer examinations if he states what disease or lesion he suspects or what question he wants answered. "Barium swallow" has meant and does mean<i>several</i>things in the mind of the referring physician. However, at the moment of requesting a "barium swallow" the clinician usually has only<i>one</i>thing in mind; unfortunately the radiologist is not a mind reader. Techniques differ; it is not simply a matter of swallowing some barium. "Barium swallow" may mean an examination of the hypopharynx or esophagus when one is looking for carcinoma, varices, cardiospasm, scleroderma, diverticula, webs, vascular rings, foreign bodies,
Lectures on Public Hygiene and Medical Police
Authors: J. Black
Journal: BMJ (1844)

There are various employments, in wbich great numbers of the inhabitants, especially of the younger caus, in all manufactuning countries, are engaged; -ad.whicb, either from the confinement in closed buildigs.orX other restricted places, or from wzpwc to the vapours of substances under nahiu&ctue, or from the manipulation of them, prove more or less detrimental to health and vigour, and many of them productive of disease, and tend- ing to shorten life.It, therefore, often falls to the duty of the medical practitioner, either from a public requisition, or from municipal or private desire of investigation, to enquire into the hygienic efects of such various employments upon the health and longevity of those exposed to their influence, in order that he may deliver an opinion how far, and in what manner, these influences extend and operte, and be enabled to point out how any ascer.tained evils or injurious tendencies may be cor- rected or removed.On some of these subjects many crude and gra.tuitous opinions have been delivered, without suffi- cient information and data having been previously acquired; and no little controversy has, from time to time, been exhibited, not much to the eredit of that-calm and philosophic spirit which at all times should characterie the investigations and evidence of professional men, when applied to, as men of science, close research, and of benevolent yet inde- pendent minds.If we were to enumerate every profession and trade that has more or less influmee on health and longevity, we might begin with those which, in common opinion, might seem rather to promote the one and to prolong the other, than to be-anywise injurios.Affluent idleness may seem to be,above the rsac of any special evil of this description; but wbas we consider the long catalogue of such dis- orders as hypochondriasis, tedium vits, dyspepsia, adsgou, to which such a life is subject, we mayNo. 3, D aWb 4, 844.
Editorial Board
Authors: Bruce Thiers, Dirk Elston, Detra Davis, Kenneth Katz, Jack Lesher, Mary Spellman, Jeffrey Weinberg, Dermatologic Surgery, Clifford Perlis, Julie Prendiville, Frcpc Dermatopathology, John Maize, Social Media, Emily Altman, Robert Dellavalle, J Smith, Editors Emeritus, Richard Dobson, Jeffrey Bernhard, Calvin Mccall, Brett Sloan, James Solomon, Stephen Tyring, George Hruza, Pediatric Dermatology, Kelly Cordoro, Dermatopathology Carlson, Tammie Ferringer, Cyberdermatology Consultant, Daniel Siegel, Clara Kim, Bryan Anderson, Salvador Arias-Santiago, Trisha Beute, John Binhlam, Diana Bolotin, Markus Braun-Falco, Nooshin Brinster, Patrick Carrington, Zoe Draelos, Nananamibia Duffy, Laura Ferris, David Fivenson, Joel Gelfand, Camille Introcaso, Nathaniel Jellinek, Jonathan Kantor, Matthew Kanzler, Kevin Kia, Nikki Levin, Kenneth Linden, Jason Lott, Omar Lupi, J Am, Acad Dermatol
Journal: Journal of the American Academy of Dermatology (2015)
Abstract 13671: GSK-3α Directly Regulates Lipid Metabolism Through Obesity-linked Phosphorylation of PPARα
Authors: Michinari Nakamura, Peiyong Zhai, Tong Liu, Hong Li, Junichi Sadoshima
Journal: Circulation (2015)

Obesity impairs lipid metabolism and leads to cardiac dysfunction, where peroxisome proliferator-activated receptor α (PPARα) serves as a key regulator of lipid metabolism. Glycogen synthase kinase-3α (GSK-3α), a serine-threonine kinase, is markedly upregulated in the heart of obese mice, suppressing glycogen synthesis. However, the functional significance of upregulated GSK-3α in lipid metabolism remains unknown. Here we show that GSK-3α directly upregulates lipid metabolism and aggravates cardiac lipotoxicity in obesity. GSK-3α activity was enhanced by palmitic acid (PA) in the nucleus in cardiomyocytes (CMs), and knockdown of GSK-3α suppressed PA-induced activation of PPARα. GSK-3α, but not GSK-3β, directly interacted with PPARα. Mass spectrometry analysis revealed that GSK-3α phosphorylates PPARα at Ser280, located in the ligand binding domain. A PPARα phospho-mimicking mutant (PPARα-S280D) exhibited an increase in both the interaction of PPARα with RXR and its DNA binding, enhancing PPARα activity and stimulating expression of lipid metabolism-related genes, including Cpt1b, CD36 and PDHK4, in CMs. High-fat diet (HFD)-fed mice displayed increased GSK-3α activity and PPARα phosphorylation in the heart. Cardiac-specific haploinsufficiency of GSK-3α normalized HFD-induced lipid accumulation (Oil Red O staining), abnormally enhanced palmitate oxidation (0.82 fold, p&lt;0.05), cardiac hypertrophy and diastolic dysfunction (0.36 fold in EDPVR, p&lt;0.05) without affecting body weight gain or food intake. While adenovirus-mediated overexpression of PPARα in the heart exacerbated HFD-induced lipid dysregulation and cardiac dysfunction, that of PPARα phospho-resistant mutant (PPARα-S280A) failed to facilitate lipid metabolism and cardiac dysfunction in the presence of a HFD. Notably, a PPARα ligand, fenofibrate, allosterically inhibited PPARα phosphorylation in obese mice by interfering with the interaction between GSK-3α and PPARα, and improved HFD-induced lipid accumulation and cardiac dysfunction. These data show that GSK-3α directly regulates lipid metabolism through Ser280 phosphorylation of PPARα, and that its phosphorylation could be a novel therapeutic target for obesity-related cardiac dysfunction.
Surgical Nursing and the Principles of Surgery for Nurses.
Journal: JAMA (1906)

The basis of this book is a series of lectures on surgical nursing given to the probationers at the London Hospital. The author states that modern nursing has passed beyond the stage of passive obedience and that a nurse must now understand the principles on which a surgeon is working. The general arrangement of the subject matter is good and the language is clear and concise. The book is well illustrated. An appendix contains formulæ for enemata of various kinds, mouth washes, eye washes and dusting powders. There are also directions for preparing nourishment for "nasal feeding," for pancreatizing and peptonizing milk, and for test meals.
Public Health Focus: Mammography
Journal: JAMA (1992)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE NEXT PHARMACOPEIA.
Journal: JAMA (1906)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Prisoner Research
Authors: Louis Lasagna
Journal: JAMA (1974)

<h3>To the Editor.—</h3> The recent "Commentary" by Dr. George Bach-y-Rita deserves a response. Dr. Bach-y-Rita has admirable concerns about the deficiencies in our penal system, and one must admire his desire to improve the lot of those incarcerated by society. I believe, however, that he has unwisely combined his desire to achieve change in prisons with an attack on all prison research, even that which is ethical and defensible. I do not accept his judgment that only those who are in "contact with the free world" can make valid decisions about the degree of risk in participation in an experiment. If Dr. Bach-y-Rita were to visit prison research facilities such as the one in Jackson, Mich, I think he would be reassured about the ability of conscientious investigators, with the aid of advisory "watchdog" bodies, to present information about participation in research that is quite adequate. My own experience with
Agricultural herbicide use and risk of lymphoma and soft-tissue sarcoma
Authors: S. K. Hoar
Journal: JAMA (1986)

A population-based case-control study of soft-tissue sarcoma (STS), Hodgkin's disease (HD), and non-Hodgkin's lymphoma (NHL) in Kansas found farm herbicide use to be associated with NHL (odds ratio [OR], 1.6; 95% confidence interval [CI], 0.9, 2.6). Relative risk of NHL increased significantly with number of days of herbicide exposure per year and latency. Men exposed to herbicides more than 20 days per year had a sixfold increased risk of NHL (OR, 6.0; 95% CI, 1.9, 19.5) relative to nonfarmers. Frequent users who mixed or applied the herbicides themselves had an OR of 8.0 (95% CI, 2.3, 27.9) for NHL. Excesses were associated with use of phenoxyacetic acid herbicides, specifically 2,4-dichlorophenoxyacetic acid. Neither STS nor HD was associated with pesticide exposure. This study confirms the reports from Sweden and several US states that NHL is associated with farm herbicide use, especially phenoxyacetic acids. It does not confirm the case-control studies or the cohort studies of pesticide manufacturers and Vietnam veterans linking herbicides to STS or HD. (<i>JAMA</i>1986;256:1141-1147)
The Ancillary Services Review Program in Massachusetts. Experience of the 1982 pilot project
Authors: R. A. Hughes
Journal: JAMA (1984)

In 1982, a pilot program to review the use of ancillary services in 25 hospitals was implemented in Massachusetts. The program analyzed hospital claims data to generate statistical models of ancillary use. Hospitals where the model demonstrated substantially higher use were subjected to clinical review. For laboratory services, three of the four hospitals reviewed were found to have more than 30% inappropriate use of selected tests, compared with approximately 20% in other hospitals. For cardiac services, three hospitals were each found to have more than 30% inappropriate use of selected tests, compared with 16% in other hospitals. When informed of these results, five of the six hospitals used them to develop plans of corrective action. Based on the pilot program, a review of ancillary services began in all Massachusetts hospitals in 1983. (<i>JAMA</i>1984;252:1727-1732)
Iron supplementation in low‐income countries
Authors: Andrew M. Prentice
Journal: HemaSphere (2018)

MRC Unit The Gambia at LSHTM, Fajara, Gambia This is an open access Abstract Book distributed under the Attribution-NonCommercial-NoDerivs (CCBY-NC-ND), which allows third parties to download the abstracts and share them with others as long as they credit the author and the abstract book, but they cannot change the content in any way or use them commercially. http://creativecommons.org/licenses/by-nc-nd/4.0
Zinc supplementation and anemia
Authors: D. A. Frambach
Journal: JAMA (1991)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Editorial Board
Authors: Zuhair Ballas, Iowa City, Iowa Deputy Editor, Stanley Szefler, Andrea Apter, Leonard Philadelphia, St Bacharier, Claus Louis, Joshua Boyce, Robert Bush, Javier Chinen, Raif Geha, Kyoto Japan, Carole Ober, David Peden, Chapel Hill, Harald Renz, Marburg Germany, Marc Rothenberg, Cincinnati Ohio, Hirohisa Saito, Tokyo Japan, Stephan Weidinger, Robert Wood, Immediate Past, Cezmi Akdis, Davos Switzerland, Amos Etzioni, James Gern, Robert Hamilton, Paul Bryce, Mariana Castells, Mitchell Grayson, Columbus Ohio, Bruce Mazer, Ariel Munitz, Kari Nadeau, Bruce Bender, Pascal Chanez, Morton Cowan, San Francisco, Elizabeth Matsui
Journal: Journal of Allergy and Clinical Immunology (2018)