tbuckley/cabot-search huggingface dataset:
Diagnostic approach to hepatic malignant neoplasms
Authors: M. Viamonte
Journal: JAMA (1977)

THE WORKUP of a patient with a possible hepatic malignant neoplasm may be generated by one or more of a variety of situations. In an asymptomatic patient, the liver disease may be detected by physical examination, from radiological studies, or from laboratory tests. More commonly, nonspecific symptoms or signs or both of malignant neoplasm or of liver disease are present. In the management of an established extrahepatic primary malignant neoplasm, evidence for metastatic disease must be sought. The following review suggests an orderly approach to establish whether or not the disease process is in the liver; whether it is neoplastic or not; and if so, whether it is benign or malignant. If it is malignant, one should ascertain whether it is primary or metastatic, characterize the extent of involvement in the liver (solitary, multiple, diffuse), and determine if it is resectable or nonresectable. If the patient has metastatic disease of
Commentaire de travail de F. J. C. van den Broek et al., pp. 116
Journal: Endoscopy (2011)

See also: Pilot study of probe-based confocal laser endomicroscopy during colonoscopic surveillance of patients with longstanding ulcerative colitisEndoscopy 2011; 43(02): 116-122DOI: 10.1055/s-0030-1255954
Erratum: Primary adhalinopathy: a common cause of autosomal recessive muscular dystrophy of variable severity
Authors: Carla Rosenberg', Ralph Florijn', Frans Van De Rijke, Lau Blonden', Tonk Raap, Gert-Jan Van Ommen', M Kamboh', Dharambir Sanghera, Robert Ferrell', Steven Dekosky'
Journal: Nature Genetics (1995)
Hormonal Therapy for Prostate Cancer in Men With Heart Disease—Reply
Authors: Akash Nanda
Journal: JAMA (2010)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Law and medicine
Authors: L. O. Gostin
Journal: JAMA (1994)

On October 27, 1993, President Clinton presented to the 103rd Congress the National Health Security Act to "ensure individual and family security through health care coverage for all Americans." Innumerable legal issues are presented by the bill, but the first portion of this review focuses on two<sup>1</sup>: (1) What exactly is an eligible individual entitled to under the bill? (2) How can hospitals and groups of health care professionals compete in a manner consistent with extant antitrust law? Eligible individuals are entitled to "medically necessary or appropriate" services under the comprehensive benefits package (section 1141). While the National Health Board is empowered to exclude specific services (section 1154), many determinations as to whether patients can be denied costineffective treatments will be determined by the courts. Although it was considered by the task force, a fair and effective administrative remedy for patients denied treatment was not included in the bill.
Der Cocainismus.
Journal: JAMA (1925)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Tetanus despite preexisting antitetanus antibody
Authors: S. A. Berger
Journal: JAMA (1978)

SINCE 1955, most cases of tetanus in New York City have occurred in heroin addicts.<sup>1</sup>Possible reasons for this include a relatively large population of addicts lacking detectable circulating antitoxin and the deep subcutaneous injection of irritating, possibly contaminated substances. With one exception in 1942,<sup>2</sup>there has been no instance of multiple tetanus cases from a common environmental source such as the drug or injection apparatus. Recently, a brother and sister were admitted to Metropolitan Hospital with tetanus following use of heroin from a single source. The disease was severe and protracted in one patient but mild in the second patient, who had preexisting serum antitoxin. <h3>Report of Cases</h3><h3>Case 1.—</h3> A 29-year-old male heroin addict had trismus and painful cervical spasms over a 24-hour period. Physical examination showed a temperature of 37.3 °C, blood pressure of 120/70 mm Hg, and pulse rate of 112 beats per minute.
From the Centers for Disease Control and Prevention. Adult blood lead epidemiology and surveillance
Journal: JAMA (1993)

MMWR. 1993;42:102-104 SINCE 1983, the Centers for Disease Control and Prevention (CDC) has published the CDC<i>Surveillance Summaries</i>under separate cover as part of the<i>MMWR</i>series. Each report published in the CDC<i>Surveillance Summaries</i>focuses on public health surveillance; surveillance findings are reported for a broad range of risk factors and health conditions. Summaries for each of the reports published in the November 20,1992, issue of the CDC<i>Surveillance Summaries</i><sup>1</sup>are provided below. All subscribers to<i>MMWR</i>receive the CDC<i>Surveillance Summaries</i>, as well as the<i>MMWR Recommendations and Reports</i>, as part of their subscriptions. MEASLES SURVEILLANCE—UNITED STATES, 1991 A total of 9643 measles cases was reported from the United States in 1991, a 65.3% decrease from the 27 786 cases reported in 1990. The overall incidence of measles was 3.9 cases per 100 000 population. The highest age-specific incidence was among children younger than 12 months
Chilaiditi's syndrome. Report of three cases
Authors: T. Melester
Journal: JAMA (1985)

PNEUMOPERITONEUM is associated with a variety of intra-abdominal pathological disorders. Interposition of the right side of the colon between the diaphragm and liver is a benign process in which the radiological appearance can be confused with more catastrophic conditions associated with pneumoperitoneum. Interposition of the right colon between the liver and the diaphragm has been described for nearly 100 years. Although the majority of cases may be merely radiological curiosities, patients may present with a variety of abdominal signs and symptoms. We present three case reports of this entity and a review of the literature. <h3>Report of Cases</h3><h3>Case 1.—</h3> A 75-year-old woman presented to the emergency room with a four-hour history of severe right upper quadrant pain with nausea and vomiting. The abdomen was mildly distended with moderate tenderness and guarding in the right upper quadrant and hyperactive bowel sounds. Roentgenograms of the chest and abdomen showed an interposed
Minerva Pediatrica, Turin
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Clinical trial in progress: Pivotal study of VB-111 combined with paclitaxel versus paclitaxel for treatment of platinum-resistant ovarian cancer (OVAL, VB-111-701/GOG-3018).
Authors: Rebecca Christian Arend, Bradley J. Monk, Thomas J. Herzog, Jonathan A. Ledermann, Kathleen N. Moore, Angeles Alvarez Secord, Ronnie Shapira-Frommer, Krishnansu Sujata Tewari, Tamar Rachmilewitz Minei, Dror Harats, Richard T. Penson
Journal: Journal of Clinical Oncology (2021)

TPS5599 Background: Ofranergene obadenovec (VB-111) is a targeted anti-cancer gene therapy with a dual mechanism of action that includes a broad antiangiogenic effect and induction of a tumor directed immune response. A phase II trial in patients with platinum resistant ovarian cancer showed that VB-111 in combination with weekly paclitaxel was well tolerated and associated with a CA-125 Objective Response Rate (ORR) of 58% with a trend for improved survival. The favorable outcomes were associated with induction of an immunotherapeutic effect of tumor infiltration with CD-8 T cells. Based on these observations, a phase III study was initiated in collaboration with the GOG Foundation, Inc. Methods: Study NCT03398655 is an international, randomized, double-blind, placebo-controlled, phase III study. Eligible patients have recurrent platinum-resistant epithelial ovarian cancer with measurable disease (RECIST 1.1), and may have been previously treated with up to 5 prior lines of therapy. Patient are randomized 1:1 to receive VB-111 (1x10 13 VPs) with weekly paclitaxel (80mg/m 2 ), or weekly paclitaxel with placebo. Randomization is stratified by number of prior treatment lines, prior antiangiogenic therapy and platinum refractory disease status. The efficacy endpoints are OS, PFS and ORR by RECIST 1.1 and by CA-125 (GCIG criteria). A pre-planned interim analysis was performed by the DSMC in the first 60 patients evaluable for CA-125 response. The analysis met the pre-defined criteria of a CA-125 ORR (GCIG) in the treatment arm at least 10% higher than in the control arm. Study enrolment is ongoing and over 220 patients were enrolled in the US, EU, and Israel. Enrolment of the full sample size of 400 patients is expected to complete by the end of 2021. Clinical trial information: NCT03398655.
Beethoven's Deafness
Journal: JAMA (1971)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Chininum. Scriptiones Collectae.
Journal: JAMA (1925)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A study of additional information given to patients with contact allergies
Journal: British Journal of Dermatology (2021)

Contact dermatitis is a type of eczema caused by contact of the skin with a particular substance in the environment. This can cause a chronic skin disease such as hand eczema and it is crucial to identify the allergy and to obtain information on where the allergen can be found. Otherwise, the eczema becomes difficult to treat and may affect a patient’s daily life and work ability. More than a quarter of the European population has been shown to have some kind of contact allergy.
Kinderärztliche Technik: Zum Gebrauch in Klinik und Praxis.
Journal: JAMA (1933)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
ABSCESS OF THE BRAIN
Journal: JAMA (1933)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Male gender is associated with a high rate of decompensation and mortality in primary biliary cholangitis with well compensated cirrhosis
Authors: Binu John, Nidah Shabbir Khakoo, Gabriella Aitcheson, Cynthia Levy, David Goldberg, Kalyan Ram Bhamidimarri, Maria Hernandez, Bassam Dahman, Yangyang Deng, Paul Martin, Tamar Taddei, David Kaplan
Journal: Journal of Hepatology (2020)
Letter: Iron fortification of wheat flour
Authors: C. E. BUTTERWORTH
Journal: JAMA (1974)

<h3>To the Editor.—</h3> The commentary of Dr. Crosby concerning iron fortification of flour (228:1651-1652, 1974) neither calls for nor merits a point-by-point response from proponents of the proposed Food and Drug Administration (FDA) regulation. It speaks for itself. Those readers who are familiar with the topic will recognize that his comment contains no new arguments, although the language has grown (indefensibly) more abusive. Readers who encounter this debate for the first time should notice how logic tends to be lost in the heat of passion. It does seem appropriate, however, to make a few general comments. This is an important and serious issue; it is perhaps only a small indication of problems that could lie ahead in the event of a nationwide disaster or food shortage. The opponents of iron fortification have made their opposition emphatically clear and a matter of public record over the past four years. However, their
Palliative Medicine
Authors: Alexie Cintron, Robert M. Arnold
Journal: JAMA (2005)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 19577: Race and Sudden Cardiac Death: Findings From the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study
Authors: Rajat Deo, Yulia Khodneva, Monika M Safford, Suzanne Judd, Elsayed Z Soliman, Michael G Shlipak, Christine M Albert
Journal: Circulation (2015)

Introduction: Blacks, as compared to whites, have a higher burden of cardiovascular disease (CVD) risk factors and CVD. Recent studies have reported a higher burden of sudden cardiac death (SCD) in blacks; however, it remains unclear whether this elevation in SCD risk is independent of racial differences in risk factor profiles and prevalent CVD. Methods: We examined the association between black race and SCD in participants with and without a history of CVD at baseline in the REGARDS study, a prospective, longitudinal cohort of 29,695 participants ≥45 years (55% women, 41% black) from across the United States. SCD was defined as sudden pulselessness from a presumed cardiac origin that occurred out of hospital or in the emergency room. Results: Over a median [IQR] of 6.0 [4.5-7.3] years of follow-up, 388 SCD events occurred. Compared to whites, blacks had less education, lower income and a higher burden of CVD risk factors. In the entire population, the age-adjusted SCD incidence rates per 1000 person-years were 2.6 (95% CI, 2.3-3.0) for blacks versus 1.7 (95% CI, 1.4-1.9) for whites, (HR=1.47; 95% CI 1.20-1.79). This elevated risk was attenuated after controlling for CVD risk factors and became non-significant after controlling for prevalent CVD (Table 1). Among the subgroup of 22,507 participants without CVD at baseline, SCD risk remained elevated in blacks (HR=1.90; 1.35-2.68) even after controlling for CVD risk factors and medication use (Table 1). In contrast, there was no elevation in SCD risk among the participants with prevalent CVD at baseline. The association between black race and SCD was stronger in those without compared to those with a history of CVD (p=0.001). Conclusions: The higher risk of SCD risk associated with black race, compared to whites, is partially explained by the higher prevalence of CVD and its risk factors in blacks. However, there remains a higher SCD risk associated with black race among those without CVD not explained by standard CVD risk factors.
Osteopenia and bone fractures in a man with anorexia nervosa and hypogonadism
Authors: N. A. Rigotti
Journal: JAMA (1986)

Women with anorexia nervosa have reduced skeletal mass. Both anorexia and osteopenia are less common in men. We describe a 22-year-old man with anorexia nervosa and severe osteopenia involving both cortical and trabecular bone who developed a pelvic fracture and multiple vertebral compression fractures. He was found to have secondary hypogonadotropic hypogonadism that was reversible with weight gain. This case illustrates the need to consider osteopenia as a potential complication of anorexia nervosa in males as well as females. (<i>JAMA</i>1986;256:385-388)