tbuckley/cabot-search huggingface dataset:
Intracranial fibromuscular hyperplasia
Authors: W. S. Elias
Journal: JAMA (1971)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Relationship Between Hormone Replacement Therapy, Socioeconomic Status, and Coronary Heart Disease
Authors: Linda L. Humphrey, Heidi D. Nelson, Benjamin K. S. Chan, Peggy Nygren, Janet Allan, Steve Teutsch
Journal: JAMA (2003)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Emphysema: Research Focuses on Etiologic Enigma
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 19415: Temperature Management After Aortic Arch Surgery With Deep Hypothermic Circulatory Arrest Affects Survival and Neurologic Outcome
Authors: Alessio Rungatscher, Giovanni Battista Luciani, Daniele Linardi, Elisabetta Milani, Leonardo Gottin, Beat Walpoth, Giuseppe Faggian
Journal: Circulation (2015)

Introduction: Therapeutic hypothermia is recommended by international guidelines after cardio-circulatory arrest. However the effect of different temperature during first 24 h after deep hypothermic circulatory arrest (DHCA) for aortic arch surgery on survival and neurologic outcome are undefined. Hypothesis: We hypothesize that target temperature management after aortic arch surgery could affect survival and neurologic outcome. Methods: In the period 2010-2014, a total of 210 consecutive patients undergoing aortic arch surgery with DHCA were included. They were retrospectively divided in three groups by median peak nasopharyngeal temperature within 24 h after rewarming: hypothermia (&lt;36°C; n = 65), normothermia (36-37°C; n = 110), hyperpyrexia (&gt;37°C; n = 35). Multivariate stepwise logistic and linear regressions were performed to determine whether different temperature independently predicted 30-day mortality, stroke incidence and neurologic outcome assessed by Cerebral Performance Category (CPC) at hospital discharge. Results: Compared with hypothermia and normothermia, hyperpyrexia was associated independently with a higher risk of 30-day mortality (35.7% vs 6.5%; odds ratio [OR], 9.4; 95% confidence interval [CI], 1.1-81.6; P= .005), stroke incidence (64.3% vs 13.3%; OR 9.3; 95% CI, 2.9-92.3; P= .002) and poor neurologic outcome (CPC 3-5) (85.7% vs 36.9%; OR 4.5; 95% CI, 0.9- 87.6; P= .01). No significant differences were demonstrated between hypothermia and normothermia. Conclusions: Post-operative hypothermia is not associated with better outcome after aortic arch surgery with DHCA. However post-operative fever (&gt;37°C) is associated with high stroke incidence, poor neurologic outcome and increased 30-day mortality. Target temperature management in the first 24 h after surgery should be evaluated in prospective randomized trials.
Deafness after topical neomycin.
Journal: BMJ (1969)

PointersBronchitis: Exacerbations found to be associ- ated with presence of pathogenic bacteria and viruses in sputum in a pilot study.No link could be shown with atmospheric pollution or cold weather (p.187).Accidents on Farms: Study of 132 patients injured in agricultural accidents showed only 9% fully immunized against tetanus.Despite legislation, safety precautions are not always followed (p.193).Influenza Viruses: Live influenza A viruses re- tained infectivity and antigenicity after attenua- tion by multiple passages at low temperatures.Further development may yield satisfactory live influenza vaccines (p.198).Viraemia proved in a case of Asian influenza (p.208).Posture in Labour: Significant increases in Po., and decreases in Pco2 found in pregnant women who sat up, compared with the levels found in lying position.Implications for posture in labour discussed (p.201).Prostatic Cancer: Liver function tests done on patients with prostatic cancer treated with oestrogens showed abnormalities in about half: these changes returned to normal if treatment continued (p.204).Appendicectomy: Ampicillin powder used in wound closure reduces rate of postoperative wound infection (p.206).Case Report: Thrombotic microangiopathy in woman with squamous carcinoma of rectum (p.209).
Edinburgh Post-Graduate Lectures in Medicine. Volume I
Journal: JAMA (1941)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Archery.
Journal: JAMA (1926)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
INCORPORATION LAWS AND MEDICINE.
Journal: JAMA (1907)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Treatment of acute intermittent porphyria with large doses of propranolol
Authors: D. Douer
Journal: JAMA (1978)

A patient had an acute attack of intermittent porphyria with severe neurologic manifestations, hypertension, and tachycardia. Treatment with propranolol hydrochloride (Deralin [Israel]; Inderal, comparable US product) intravenously administered in a total dose of 284 mg during a period of 18 hours, was followed by clinical remission associated with a decline in urinary excretion of porphyrin precursors. (<i>JAMA</i>240:766-768, 1978)
Primary small cell carcinoma of the esophagus: Retropective analysis of the Veterans Affairs Cancer Registry.
Authors: Mahmoud Abu Hazeem, Ramya Thota, Shanmuga Subbiah
Journal: Journal of Clinical Oncology (2012)

32 Background: Small cell carcinoma (SCC) of the esophagus is a rare aggressive and rapidly fatal neoplasm, often diagnosed in late stages. Hence no prospective studies evaluating the most effective treatment strategies have been done. We aim to describe the clinicopathological features and treatment outcomes of this rare entity. Methods: Retrospective analysis of 49 patients diagnosed with SCC of the esophagus from 1995 to 2009 was done via the Veteran's Affairs Central Cancer Registry. Demographics, staging, treatment, and outcomes data was recorded. Staging was classified as limited (no distant metastasis) or extensive stage (metastatic disease). Results: Out of 10,540 patients with esophageal cancer, 49 were diagnosed with SCC (0.005%) and were mainly located in the middle and lower thirds of the esophagus (84%). Median age of diagnosis was 64.1 yrs (range: 26-90). 19 patients had limited disease, 26 patients had extensive disease and four patients who were not staged adequately were excluded. Patients received a variety of treatments (Table) with different survival outcomes. Limited stage SCC patients had a median survival of 6.3 mos with patients who received combined modality therapy showing a trend towards improved outcomes. Extensive stage patients who received no therapy had very poor outcomes compared to patients who received any therapy. Conclusions: SCC of esophagus should be considered a systemic disease and like pulmonary SCC, it is an aggressive tumor associated with a poor prognosis. Patient numbers are too low to draw definitive conclusions regarding choice of therapy. Extensive disease patients benefit from chemotherapy and combined modality therapy should be considered in limited stage disease. [Table: see text]
Biopersistence of the Mineral Matter of Coal Mine Dusts in Silicotic Human Lungs: Is There a Preferential Release of Iron?
Authors: Jean-Luc Tourmann, Raimund Kaufmann
Journal: Environmental Health Perspectives (1994)

Toxic potency of quartz-containing dusts, including coal mine dusts, is usually inhibited by protective clay mineral layers on the surface of quartz par- ticles.This investigation of 11 dusts recovered from lungs of coal miners with different silicosis grade shows that such layers persist during long- term contact with human lung tissues.On the other hand, the results suggest that an apparently preferential release of iron occurred in lungs with massive fibrosis.These preliminary results support the hypothesis of an iron-related harmfulness of coal mine dusts.-Environ Health Perspect 102(Suppl 5):265-268 (1994) Key words: coal workers pneumoconiosis, lung dusts,
Gestational surrogacy
Authors: Peter R Brinsden
Journal: Human Reproduction Update (2003)

Gestational surrogacy is a treatment option available to women with certain clearly defined medical problems, usually an absent uterus, to help them have their own genetic children. IVF allows the creation of embryos from the gametes of the commissioning couple and subsequent transfer of these embryos to the uterus of a surrogate host. The indications for treatment include absent uterus, recurrent miscarriage, repeated failure of IVF and certain medical conditions. Treatment by gestational surrogacy is straightforward and follows routine IVF procedures for the commissioning mother, with the transfer of fresh or frozen-thawed embryos to the surrogate host. The results of treatment are good, as would be expected from the transfer of embryos derived from young women and transferred to fit, fertile women who are also young. Clinical pregnancy rates achieved in large series are up to 40% per transfer and series have reported 60% of hosts achieving live births. The majority of ethical or legal problems that have arisen out of surrogacy have been from natural or partial surrogacy arrangements. The experience of gestational surrogacy has been largely complication-free and early results of the follow-up of children, commissioning couples and surrogates are reassuring. In conclusion, gestational surrogacy arrangements are carried out in a few European countries and in the USA. The results of treatment are satisfactory and the incidence of major ethical or legal complications has been limited. IVF surrogacy is therefore a successful treatment for a small group of women who would otherwise not be able to have their own genetic children.
Low back pain.
Authors: A Frank
Journal: BMJ (1993)

The studies reviewed here show that the duration and severity of individual episodes of back pain can be lessened, reducing recurrences and their cost in terms of suffering and lost work. Frank examines differential diagnosis; acute, chronic, and intractable pain; and service implications. Modern management emphasises self care, and bed rest should usually not be longer than 48 hours. A return to physical fitness and other activities, including employment, is actively encouraged. Medication has a role in facilitating these objectives. Two points are especially emphasised: strategies to manage low back pain must be long term and preventive; and the responsibility to keep fit, maintain an exercise programme, and remain relaxed so as to avoid physically stressing the spine is that of the individual, not of the professionals.
Insulin injections: rotation of anatomic regions and plasma glucose
Authors: R. K. Bernstein
Journal: JAMA (1990)

<h3>To the Editor.—</h3> The recent report by Bantle et al<sup>1</sup>demonstrates for the first time in a controlled fashion what many insulin-using patients have observed since self-monitoring of blood glucose began in 1969. Injections of<i>large</i>boluses of insulin produce highly variable effects on blood glucose levels. Bantle et al found that this variation was nearly doubled when injection sites were rotated. Nevertheless, it was still so great when sites were restricted to the abdomen that near-normal blood glucose levels were not reported. I take exception to the conclusion of the authors that if their results are confirmed in additional studies, "rotation of the regions used for insulin injections should be replaced by use of a single anatomic region for all injections." Patients who inject large boluses of insulin over and over in the same sites tend to develop subcutaneous deposits of fibrous tissue. They indicate awareness of this
Ingestion of mouthwash by children
Journal: BMJ (1999)

eight control patients who developed nephropathy was 27.3 (3.7 to 51.0; P = 0.03) while glomerular filtration rate increased by 3.8 ( -3.5 to 11.0) in the six patients treated with captopril with urinary albumin excretion > 300 mg/24 h during the treatment pause (P = 0.02 between the groups).Haemoglobin A 1c and blood pressure did not differ between the two groups at any time during the study.
Health-related spin-offs of space exploration
Journal: JAMA (1978)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Beyond universal health insurance to effective health care
Authors: E. Ginzberg
Journal: JAMA (1991)

NO ONE, least of all an economist, needs to be persuaded that people who lack money or health insurance are likely to encounter difficulties in obtaining essential health care services. On the other hand, the economist has an obligation to explain that the adoption of a system of universal coverage will not, ipso facto, translate into assured access for essential, much less optimal, health care for those who are currently disadvantaged. The reasons that universal coverage will not necessarily guarantee effective services to all are embedded in the nature and characteristics of the health care system. In developing this argument and its policy implications, we will undertake a threefold analysis, including (1) a selective review of health care financing reforms in the United States, (2) an explication of nonfinancial barriers to effective health care, and (3) a delineation of the range of interim policy interventions required to lower the barriers
Apoptosis in experimental hepatitis . 1Experimental and 2Gastroenterology Unit, Hospital Reina Sofia, C�rdoba, Spain
Journal: Hepatology (1995)

Several hepatitis B virus (HBV) subgenotypes, HBV/A1, A2, Bj and Ba, have been reported with respect to clinical differences among patients infected with these subgenotypes. The population genetics and phylogeography of HBV were investigated based on the complete genome sequences of 484 isolates with 108 from our chronic hepatitis B patients and the remaining from the GenBank database. Besides genotypes A–H (HBV/A–H), five subgenotypes were identified among 169 HBV/B isolates by phylogenetic analysis and nucleotide divergence. There were 27 isolates of subgenotype B1 (HBV/B1) restricted to Japan, 104 isolates of HBV/B2 with the widest distribution in most Asian countries, 4 isolates of HBV/B3 restricted to Indonesia, 32 isolates of HBV/B4 restricted to Vietnam, and 7 isolates of HBV/B5 restricted to Philippines. HBV/B2–B5 isolates carried a recombination with HBV/C over the precore and core genes. In addition to the characteristics of HBV/B1–B5 at some cis-acting elements, the precore stop-codon mutant (G1896A) was significantly different among HBV/B1, HBV/B2, and HBV/B4 (70.3%, 31.7%, 53.0%, P = 0.001), while no such mutation was found in HBV/B3 and B5. Among characteristics of the HBV/B1–B5 amino acid sequences, serotype adw (K122) was exclusive among HBV/B1, HBV/B2, and HB V/B3 isolates, while serotype ayw (R122) was among the HBV/B4 and HBV/B5 isolates. Furthermore, distinct variations of T cell and B cell recognition epitopes within surface and core proteins were also found among these subgenotypes. In conclusion, subgenotypes HBV/B1–B5 exhibited distinct geographical distributions, virologic characteristics, and probable clinical implications.