tbuckley/cabot-search huggingface dataset:
Changes in the Cigarette Brand Preferences of Adolescent Smokers—United States, 1989-1993
Journal: JAMA (1994)

Approximately three million U.S. adolescents are smokers, and they smoke nearly one billion packs of cigarettes each year. The average age at which smokers try their first cigarette is 14 1/2 years, and approximately 70% of smokers become regular smokers by age 18 years. Evaluating the changes in the brand preferences of young smokers can help identify factors that influence adolescents' brand choice and may suggest smoking-prevention strategies. This report examines changes in the brand preferences of teenaged smokers from 1989 to 1993 using data from CDC's 1993 Teenage Attitudes and Practices Survey (TAPS-II) and comparing them with data from the 1989 TAPS.
Serious flaws mar many cancer therapy trials
Authors: J. Henahan
Journal: JAMA (1983)

Poor patient selection, inadequate follow-up, and premature reporting of results are among the factors that may obfuscate the meaning of many clinical trials in cancer medicine, according to several participants in the Sixth Annual Bristol-Myers Symposium on Cancer Research, held this year in Venice. For example, Umberto Veronesi, MD, director general of the Italian National Cancer Institute in Milan, pointed out that although 100 different trials on the use of chemotherapy or radiation therapy as an adjunct to cancer surgery were carried out in 1982 alone, the results in many were unconvincing or contradictory. The main flaw in such trials is that they provide little information as to the best time to administer adjunctive therapy. "A correct design for a trial on the efficacy of adjunctive surgical node dissection and/or of postoperative radiotherapy or adjunctive chemotherapy must explore their differential efficacies when applied 'earlier' [when presumptive metastases may be occult]
Casopis Lekaru Ceskych, Prague
Journal: JAMA (1967)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
NECROLOGY.
Journal: JAMA (1893)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Consumer Choices and the American Health Care System
Authors: Timothy N. Gorski
Journal: JAMA (1992)

<h3>To the Editor.</h3> —Dr Reiser<sup>1</sup>makes some excellent observations and recommendations concerning current problems with the American health care system. But I fail to appreciate why he states that funding for health care, at least for the general population, "should come from workers, employers, and government," or why "an equal contribution by each is needed to spread the financial burden of health care." Government dollars, after all, are nothing but the dollars of the productive members of society (ie, workers), that have been extracted from them by taxation, less a handling fee. Similarly, employer-paid health insurance is merely a wage equivalent that factors into the economic reality of the labor market. I would like to see the tort law, insurance, and market incentive reforms that Reiser suggests. But I see no benefits in creating additional government involvement in the health care of the general population. Why should medicine be
Prolonged Weakness and Vecuronium
Authors: Victor L. Scott
Journal: Annals of Internal Medicine (1993)

Letters1 April 1993Prolonged Weakness and VecuroniumVictor L. Scott, MD, Judith A. Freeman, MD, and Andre M. DeWolf, MDVictor L. Scott, MDSearch for more papers by this author, Judith A. Freeman, MDSearch for more papers by this author, and Andre M. DeWolf, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-118-7-199304010-00018 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:We agree with Kupfer and colleagues' [1] comments about the necessity of monitoring neuromuscular transmission and feel that this prospective study would have been enhanced by titrating the dose of vecuronium to a monitored end point, thereby excluding the possibility of overdose as a cause for prolonged paralysis, as probably occurred in Patients 3 and 10. In addition, the 3-desacetylvecuronium metabolite is approximately 50% to 60% as potent as the parent compound and accumulates in the presence of hepatic and renal insufficiency [2]. Had the authors measured serum levels of both vecuronium and its metabolite, they might ...References1. Kupfer Y, Namba T, Kaldawi E, Tessler S. Prolonged weakness after long-term infusion of vecuronium bromide. Ann Intern Med. 1992; 117:484-6. Google Scholar2. Segredo V, Caldwell JE, Matthay MA, Sharma ML, Gruenke LD, Miller RD. Persistent paralysis in critically ill patients after long-term administration of vecuronium. N Engl J Med. 1992; 327:524-8. Google Scholar3. Margolis BD, Khachikian D, Friedman Y, Garrard C. Prolonged reversible quadriparesis in mechanically ventilated patients who received long-term infusions of vecuronium. Chest. 1991; 100:877-8. Google Scholar4. Subramony SH, Carpenter DE, Raju S, Pride M, Evans OB. Myopathy and prolonged neuromuscular blockade after lung transplant. Crit Care Med. 1991; 19:1580-2. Google Scholar5. Danon MJ, Carpenter S. Myopathy with thick filament (myosin) loss following prolonged paralysis with vecuronium during steroid treatment. Muscle Nerve. 1991; 14:1131-9. Google Scholar Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDiseases of the Peripheral Nervous System 1 April 1993Volume 118, Issue 7Page: 569-571KeywordsAtrophyDrugsMetabolitesMuscle biopsiesMusclesNeuromuscular blockadeNeuropathyParalysisProspective studiesSteroids ePublished: 15 August 2000 Issue Published: 1 April 1993 Copyright & PermissionsCopyright © 1993 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Postpartum thyrotoxicosis in a patient with Graves' disease. Association with low radioactive iodine uptake
Authors: R. H. Eckel
Journal: JAMA (1980)

A patient with previously diagnosed Graves' hyperthyroidism had a transient episode of thyrotoxicosis three months postpartum. This was associated with a diffusely enlarged thyroid gland, a rise in antithyroid microsomal antibody titer, a 24-hour radioactive iodine uptake (RAIU) of 1%, and an aspiration biopsy specimen suggestive of chronic lymphocytic thyroiditis. An alternative cause for the depressed RAIU was not discovered. This case would suggest that patients with previously diagnosed Graves' disease can have thyrotoxicosis without an enhanced RAIU and that the postpartum thyrotoxic syndrome may involve an immunologic injury causing a release of preformed thyroid hormone. (<i>JAMA</i>243:1454-1456, 1980)
Etiquette: preaching and teaching
Authors: M. T. Rabkin
Journal: JAMA (1988)

At the medical schools and teaching hospitals and at community hospitals, too, senior physicians not only educate their juniors in the substance of medicine but communicate as well<i>how</i>to be a doctor. While the former leans heavily on data and facts, the latter is conveyed largely by individual example, that is, by the physician serving as role model. Being an example to others is not an option; it is inevitable in virtually every interaction on the part of the physician. Even walking the hospital corridor, conversing with a colleague, patient, or visitor, the physician is registering with passersby. The impact is more intense, of course, on those enmeshed with the physician in the tasks of the moment, but always the physician is demonstrating how he or she behaves in specific circumstances. To your juniors, your actions take on normative qualities. Who does not recall mentors from medical school and
Transcutaneous Ultrasound Augments Naked DNA Transfection of Skeletal Muscle
Authors: P SCHRATZBERGER, J KRAININ, G SCHRATZBERGER, M SILVER, H MA, M KEARNEY, R ZUK, A BRISKEN, D LOSORDO, J ISNER
Journal: Molecular Therapy (2002)

This study was designed to test the hypothesis that transcutaneous ultrasound (US) exposure may augment the transfection efficiency and biological outcome associated with nonviral DNA gene transfer. Hindlimb muscles of New Zealand White rabbits were transfected with the reporter plasmid pCMV-β, with or without US exposure. Optimization studies employed US exposure at various frequencies, mechanical indices, duty cycles, durations of exposure, and exposure time points. Based on these results, we explored the effect of US exposure on nonviral gene transfer of vascular endothelial growth factor (VEGF, phVEGF165) to promote neovascularization of ischemic hindlimbs. Ultrasound at 1 MHz, 100 W/cm2, 6% duty cycle, and 5 minutes exposure time, applied immediately following DNA injection, was found to be the most effective among the settings tested, increasing β-galactosidase expression ∼20 fold. Compared with US exposure alone, or phVEGF165 only, phVEGF165 + US exposure yielded a statistically significant improvement in revascularization, as determined by calf blood pressure ratio, angiographic score, intravascular Doppler blood flow, and capillary/myocyte ratio. These data demonstrate that ultrasound, when applied directly after intramuscular gene transfer, significantly increases transfection efficiency in vivo. The biological significance of this finding was confirmed by augmented limb perfusion in response to US exposure and naked VEGF DNA.
In Brief
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Long-Term Follow-up of Rituximab and Infusional Cyclophosphamide, Doxorubicin, and Etoposide (CDE) In Combination with HAART In HIV-Related Non-Hodgkin's Lymphomas (NHL)
Authors: Michele Spina, Ulrich Jaeger, Joseph A Sparano, Renato Talamini, Giuseppe Rossi, Emanuela Vaccher, Umberto Tirelli
Journal: Blood (2010)
Immunologic phenomena in burn injuries
Authors: J. W. Alexander
Journal: JAMA (1967)

Bacterial infections continue to cause more deaths following severe thermal injury than any other single factor, and a depression of the defense mechanism is felt by many to contribute significantly to this apparent increased susceptibility to infection. An important part of the overall host defense mechanism is the ability to produce specific antibody in response to an antigenic stimulus. This aspect has been studied incompletely following thermal injury, even though both active and passive immunity to certain bacteria have been shown to prevent progressive bacterial invasion in burn wounds and surgical wounds of experimental animals. Alexander and co-workers<sup>1</sup>have been able to induce good protection against infection by<i>Pseudomonas aeruginosa</i>by immunization with a purified extract of the organism. Feller et al,<sup>2</sup>Walker et al,<sup>3</sup>and McMeel et al<sup>4</sup>obtained similar protection with whole cell vaccines to a single strain of<i>Pseudomonas</i>. Jones and Luwbury<sup>5</sup>
Brief Report: Investigation into Recalled Human Tissue for Transplantation—United States, 2005-2006
Journal: JAMA (2006)

On September 29, 2005, a human tissue-processing company discovered inaccuracies in donor records forwarded from a tissue-recovery firm and notified the Food and Drug Administration (FDA). An FDA investigation determined that the recovery firm, Biomedical Tissue Services, Ltd. (BTS) (Fort Lee, New Jersey), recovered tissues from human donors who might not have met donor eligibility requirements and who were not screened properly for certain infectious diseases. In October 2005, BTS and the five processors that had received the tissues, working with FDA, issued a recall for all tissues recovered by BTS. The continuing FDA investigation determined that information for some donors (e.g., cause, place, or time of death) was not consistent with death certificate data obtained from the states where the deaths occurred. The investigation also determined that BTS had failed to recover tissues in a manner that would prevent contamination or cross-contamination and failed to control environmental conditions adequately during tissue recovery. These failures were violations of the Current Good Tissue Practice Rules (effective May 25, 2005), which require manufacturers to recover, process, store, label, package, and distribute human cells, tissue, and cellular and tissue-based products (HCT/Ps) to prevent introduction, transmission, or spread of communicable diseases. In January 2006, FDA ordered BTS to cease manufacturing and to retain all HCT/Ps.
SELECTION.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Angina Pectoris and Carbon Monoxide
Authors: JAMES THEODORE
Journal: Annals of Internal Medicine (1973)

Comments and Corrections1 April 1973Angina Pectoris and Carbon MonoxideJAMES THEODORE, M.D.JAMES THEODORE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-78-4-611_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: There are several serious questions that should be raised concerning the lead article in the November 1972 issue (pp. 669-676), "Effect of Freeway Travel on Angina Pectoris" by W. S. Aronow and associates, which was enthusiastically endorsed by an editorial in the same issue (pp. 808-810). The criticisms fall into three major categories: [1] validity of carboxyhemoglobin levels measured, [2] design of the study, and [3] conclusions drawn from the results.1. The levels of carboxyhemoglobin reported by the authors in their subjects after 90 minutes of breathing "freeway air" would appear to be suspect. In fact,...Reference1. PETERSONSTEWART JR: Absorption and elimination of carbon monoxide by inactive young men. Arch Environ Health 21:165-171, 1970 CrossrefMedlineGoogle Scholar1. GOLDSMITHTERZAGHIHACKNEY JJJ: Evaluation of fluctuating carbon monoxide exposures. Arch Environ Health 7:647-663, 1963 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 April 1973Volume 78, Issue 4Page: 611-613KeywordsAnginaBreathingCarbon monoxideCarboxyhemoglobinFalls Issue Published: 1 April 1973 PDF downloadLoading ...
Authors' Reply
Authors: Randall S Stafford, Veronica Monti, Jun Ma
Journal: PLoS Medicine (2006)

I would like to thank PLoS Medicine for publishing Lacasse and Leo's important and methodical Essay that debunks the "chemical imbalance" advertisements for psychiatric drugs [1].Why would the United States Food and Drug Administration (FDA) approve such ads?Our human rights group, MindFreedom International, has been asking that question for a long time.On behalf of MindFreedom, US Senator Ron Wyden contacted the FDA for an explanation about why they approve such advertising.In their responsewhich took over one year to receive-the FDA could cite no scientifi c literature or studies.It turns out there's a good reason that the FDA can't fi nd any scientifi c evidence for the claims of a "chemical imbalance" in these ads: the scientifi c evidence in support of the serotonin hypothesis is very weak.Readers who would like more information about the psychiatric industry's advertising suggesting a "chemical imbalance" in depression may be interested in the following:(1) MindFreedom's debate with Pfi zer, manufacturer of Zoloft, available at http:⁄⁄www.mindfreedom.org/mindfreedom/pfi zerlies.shtml,and (2) a historic debate with the American Psychiatric Association resulting from MindFreedom's 2003 hunger strike, available at http:⁄⁄www.mindfreedom.org/mindfreedom/hungerstrike.shtml
Contents
Authors: R Moreau, R Bataller, T Berg, J Zucman-Rossi, R Jalan, J Roberto, P Jordi Bruix, Craxı Antonio, A Toubal, A Lehuen, H Chan, S Ahn, T.-T Chang, C.-Y Peng, D Wong, C Coffin, S Lim, P.-J Chen, H Janssen, P Marcellin, L Serfaty, S Zeuzem, D Cohen, L Critelli, D Xu, M Wind-Rotolo, E Cooney, H Midgard, B Bjøro, A Maeland, Z Konopski, H Kileng, J Dama, J Paulsen, L Heggelund, P Sandvei, J Ringstad, L Karlsen, K Stene-Johansen, -O Pettersson, D Dorenberg, O Dalgard, P Udompap, A Mannalithara, N.-Y Heo, D Kim, W Kim, L Allweiss, S Gass, K Giersch, A Groth, J Kah, T Volz, G Rapp, A Scho, A Lohse, S Polywka, S Pischke, E Herker, M Dandri, M Lu ¨tgehetmann, A Boussif, L Rolas, E Weiss, H Bouriche, A Pe ´rianin, M ´beda, M Lario, L Mun ˜oz, M.-J Borrero, M Rodrı ´guez-Serrano, A.-M Sa ´nchez-Dı ´az, R Del Campo, L Lledo, O Pastor, L Garcı ´a-Bermejo, D Dı ´az, M A ´lvarez-Mon, A Albillos, M Mcphail, D Shawcross, M Lewis, I Coltart, E Want, C Antoniades, K Veselkov, E Triantafyllou, V Patel, O Pop, M Gomez-Romero, M Kyriakides, R Zia, R Abeles, M Crossey, W Jassem, J Oõgrady, N Heaton, G Auzinger, W Bernal, A Quaglia, M Coen, J Nicholson, J Wendon, E Holmes, S Taylor-Robinson, Y Nagamoto, K Takayama, K Ohashi, R Okamoto, F Sakurai, M Tachibana, K Kawabata, H Mizuguchi, C Qu, D He, X Lu, L Dong, Y Zhu, Q Zhao, X Jiang, P Chang, L Wang, Y Zhang, L Bi, J He, Y Peng, J Su, H Zhang, H Huang, Y Li, S Zhou, Y Qu, Y Zhao, Z Zhang, R Lencioni, J Llovet, G Han, W Tak, J Yang, A Guglielmi, S Paik, M Reig, G.-Y Chau, A Luca, L Del Arbol, M.-A Leberre, W Niu, K Nicholson, G Meinhardt, J Bruix, S Choi, J Byun, Y.-S Lim, E Yu, S Lee, S Kim, H Won, Y Shin, P Kim
Journal: Journal of Hepatology (2016)
Hunterian Lectures ON MAN'S POSTURE: ITS EVOLUTION AND DISORDERS: Given at the Royal College of Surgeons of England
Authors: A. Keith
Journal: BMJ (1923)

THE true story of how anetomists abaandoned the belief that man's body was a special creation and became converted to the theory of evolution commences in 1809, the year of Darwin's birth-whenEngland aEwl France were striving for
The Chest Roentgenologically Considered.
Journal: JAMA (1930)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal