tbuckley/cabot-search huggingface dataset:
Report on America's Relief Expedition to Asia Minor Under the Red Cross.
Journal: JAMA (1897)

This report is published for the benefit of the Armenian sufferers, and is an interesting narrative of the expedition. The illustrations are numerous and instructive. Miss Barton and her corps have placed here an enduring record of her latest and best work in the cause of humanity. Nothing is set down in malice, nor are the instances of misgovernment by the "unspeakable Turk" shielded. The constant courtesy and respectful treatment of the Turkish Government is acknowledged. The report is a plain unvarnished tale of human misery and suffering, phenomenal cruelty of the Mussulman, and heroic efforts of relief by a philanthropic society.
What's new in the other general journals
Authors: Alison Tonks
Journal: BMJ (2006)

Antidepressants such as fluoxetine are a common treatment for anorexia nervosa, even though there's no evidence that they help with weight gain. A new trial has found that fluoxetine doesn't prevent relapses either, a disappointing result given the high rate of relapse and the high risk of all cause mortality associated with this common mental illness. The trial was relatively small (n = 93) but well done, and a linked editorial (pp 2659-60) describes it as convincingly negative. Compared with placebo, fluoxetine did not prolong remission in women aged 16-45 who had recovered after initial treatment. Time to relapse was similar in both groups, and only 26.5% of the women taking fluoxetine and 31.5% of those taking a placebo managed to continue with treatment and keep their body mass index above 18.5 during the trial, which lasted one year. All the participants had cognitive behaviour therapy. Credit: JAMA As expected, dropout rates were high. Only 40 of the 93 women completed their course of treatment. They were equally likely to drop out of placebo and treatment groups. The editorial says this trial leaves doctors with few if any drug options for young women with anorexia, partly because the research effort so far has not matched the importance of this disease. Anorexia is associated with a higher risk of suicide than any other mental illness. JAMA2006;295: 2605–12 [OpenUrl][1][CrossRef][2][PubMed][3][Web of Science][4] Nitazoxanide is an antidiarrhoeal agent already licensed in the United States to treat diarrhoea caused by Cryptosporidium spp and Giardia spp. It also seems to work against rotavirus, the commonest cause of life threatening diarrhoea in children worldwide. In a small randomised trial sponsored by the drug's manufacturer, nitazoxanide halved the time it took for Egyptian children to get better after being admitted to hospital with severe rotavirus infection. The 38 children who took part had … [1]: {openurl}?query=rft.jtitle%253DJAMA%26rft.stitle%253DJAMA%26rft.issn%253D0002-9955%26rft.aulast%253DWalsh%26rft.auinit1%253DB.%2BT.%26rft.volume%253D295%26rft.issue%253D22%26rft.spage%253D2605%26rft.epage%253D2612%26rft.atitle%253DFluoxetine%2Bafter%2Bweight%2Brestoration%2Bin%2Banorexia%2Bnervosa%253A%2Ba%2Brandomized%2Bcontrolled%2Btrial.%26rft_id%253Dinfo%253Adoi%252F10.1001%252Fjama.295.22.2605%26rft_id%253Dinfo%253Apmid%252F16772623%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/external-ref?access_num=10.1001/jama.295.22.2605&link_type=DOI [3]: /lookup/external-ref?access_num=16772623&link_type=MED&atom=%2Fbmj%2F332%2F7556%2F1500.atom [4]: /lookup/external-ref?access_num=000238224000022&link_type=ISI
Cause of death in the very old
Journal: JAMA (1982)

<h3>To the Editor.—</h3> It has been noted that the greatest tragedies in medicine occur when routine is broken. Unfortunately, this situation is prevalent when care is directed to our colleagues. Even when an effort is made not to "do anything special," this may conversely cause undue conservatism or hesitation at times of therapeutic urgency. Judgment is confounded by our own recognition of possible emotional involvement, making decision more difficult and action seem more perilous. I am sure most of us can relate to these stresses, but we also lack a prepared psychological praxis for these special circumstances. A common way to proceed when a fellow physician, important person, or hospital staff member requires treatment is to boost the patient to the "professor's service." This maneuver often compounds the issues already mentioned, while abdicating our responsibility and also therapeutic contribution. I do not have my own answer to this problem, but
Infusion of H2O2 Raises O2 Concentration in Tissue
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Erratum
Authors: Matthias Berking, David Ebert, Pim Cuijpers, Stefan G. Hofmann, Kerstin Jung, Regina Steil, Martin Bohus, Anne S. Dyer, Kathlen Priebe, Antje Krüger, Nikolaus Kleindienst, Christian Schmahl, Inga Niedtfeld, Regina Steil, Austyn Snowden, Hasse Karlsson, Jussi Hirvonen, Jouko Salminen, Jarmo Hietala, Wolfram Schüffel, Battuvshin Lkhagvasuren, Tomoaki Masuno, Yoshio Kanemitsu, Nobuyuki Sudo, Chiharu Kubo, Takakazu Oka, Giovanni A. Fava, Richard Balon, R. Delle Chiaie, G. Trabucchi, Elfriede Greimel, Martha Dorfer, David J. Houlihan, Elena Tomba, N. Girardi, I. Marini, R. Pannese, L. Vergnani, M. Caredda, M.P. Zerella, A. Minichino, A. Corrado, F.R. Patacchioli, S. Simeoni, M. Biondi, Michaela Lambauer, Vesna Bjelic-Radisic, Susanne Gramm, Manfred Lahousen, Uwe Lang, Marijke L. Swart, Annette M. van Schagen, Jaap Lancee, Jan van den Bout, Per Bech, David Ebert, Torsten Tarnowski, Mario Gollwitzer, Bernhard Sieland, Matthias Berking, Satz Mengensatzproduktion, Druck Reinhardt Druck Basel, Druck Reinhardt Druck Basel
Journal: Psychotherapy and Psychosomatics (2013)
Abstract 946: Angiotensin II Type 1 Receptor Partially Mediates Stretch-Induced Potentiation of the Slow Component of Delayed Rectifier Potassium Current in Guinea Pig Atrium
Authors: Dimitar P Zankov, Futoshi Toyoda, Mariko Omatsu-Kanbe, Hiroshi Matsuura, Minoru Horie
Journal: Circulation (2007)

Introduction: Mechano-sensitive signal transduction in atrial myocytes is closely related to the development of atrial fibrillation (AF). A repolarizing conductance in the heart stimulated by stretch or swelling of myocytes is the slow component of the delayed rectifier K + current ( I Ks ). Modulation of I Ks appears to be linked to pathogenesis of AF because in hereditary cases, gain-of-function mutations in I Ks channel genes have been detected. Moreover, membrane stretch activates AT 1 receptor even without angiotensin II. Hypothesis: We assessed the hypothesis that activation of AT 1 receptor mediates swelling-induced increase of I Ks in atrium. Methods: Whole-cell patch-clamp method was used to record I Ks and action potentials in guinea pig atrial myocytes. Results: Exposure of atrial myocytes to 70% hyposmotic solution (210 mOsmol/L, HS) enhanced I Ks by 84.1± 8.4% ( n = 12), abbreviated atrial action potential at 90% repolarization (APD 90 ) by 16.8± 1.3%, and depolarized resting potential by 4.9±0.7 mV ( n = 9). Selective blockade of AT 1 receptor with 1 or 5 μmol/L candesartan and 5 μmol/L olmesartan significantly attenuated the HS-induced I Ks increase to 48.0±4.1% ( n = 10), 47.2±2.7% ( n = 9), and 59.4±5.5% ( n = 9), respectively. Pretreatment with 5 μmol/L olmesartan also significantly reduced the HS-evoked shortening of APD 90 to 12.4± 1.4% ( n = 10). Tyrosine kinase inhibitors tyrphostins A23 and A25 (20 μmol/L) reduced the HS-induced I Ks enhancement to 42.0± 9.5 ( n = 13) and 52.7±4.7% ( n = 12), respectively, whereas their inactive analogue A1 had little effect. Block of tyrosine phosphatases by 500 μmol/L orthovanadate further promoted the potentiation of I Ks by HS to 124.6± 10.6% ( n = 8) and markedly decreased the recovery rate of I Ks after withdrawal of HS. Pharmacological suppression of G proteins, phospholipase C, and protein kinase C did not appreciably affect the modulation of I Ks . Conclusion: These results indicate involvement of AT 1 receptor and tyrosine kinases in the hyposmotic potentiation of atrial I Ks . It is likely that in the clinical settings, AT 1 receptor antagonists can attenuate the stretch-induced I Ks increase and action potential shortening and thereby exert an acute antiarrhythmic action on stretch-related atrial arrhythmias such as AF.
CARBURETTED WATER—GAS.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Medical Ethics
Authors: Robert M. Veatch
Journal: JAMA (1979)

In the field of medical ethics, a year is such a thin sliver of time that the events capturing attention are to some extent accidents of history. Medical ethics, like the more general problems of ethics (of which it is a part), is best perceived from a perspective of centuries rather than months. Even so, several events of the past year have been of compelling interest to people concerned with problems of ethics in medicine. These issues have pressed themselves alike on scholars working in the field, on clinicians struggling with decisions in their daily practice, on administrators in professional and government organizations, and on people trying to be responsible patients. <h3>Decisions for Incompetent Patients</h3> Late in 1977 the Massachusetts Supreme Court issued a written opinion explaining why it had intervened to order physicians to stop treating Joseph Saikewicz.<sup>1</sup>Saikewicz was a 67-year-old man suffering from acute myeloblastic monocytic
Sensory and Pulmonary Irritation of Methyl Isocyanate in Mice and Pulmonary Irritation and Possible Cyanidelike Effects of Methyl Isocyanate in Guinea Pigs
Authors: Y. Alarie, J. S. Ferguson, M. F. Stock, D. A. Weyel, M. Schaper
Journal: Environmental Health Perspectives (1987)

Methyl isocyanate (MIC) was evaluated for sensory and pulmonary irritation in mice. MIC was found to be both a potent sensory and pulmonary irritant in this species. From these results, a safe level of exposure for a period of 8 hr was estimated to be about 0.02 ppm for humans. Guinea pigs were also exposed to MIC for a single 3-hr exposure at a concentration of 37 ppm. During exposure to MIC, coughing was observed in all animals. Pulmonary function was evaluated immediately following exposure and intermittently on the next 35 days using CO2 challenges and flow-volume loops. Highly abnormal responses to CO2 were observed immediately after exposure in all animals. Six of the eight animals exposed to MIC died. In the two survivors, an apparent recovery was seen during the 5 days following exposure, but a worsening effect was observed at days 21 and 28, with a partial recovery at day 35. The data clearly demonstrated that the primary pulmonary effect of MIC was one of airways obstruction. Oxygen uptake and carbon dioxide output were also measured in the guinea pigs following exposure to MIC. No evidence of a cyanidelike effect was observed, in contrast to a severe depression of oxygen uptake following exposure to hydrogen cyanide.
Carcinoma of the breast. Stage II--radiation range. The advantages of preoperative irradiation
Authors: G. H. Fletcher
Journal: JAMA (1967)

This report<sup>25</sup>is a continuation of a study previously reported.<sup>17</sup>In the present study, 1,243 patients with histologically proved carcinoma of the breast received definitive therapy by one of four methods. <h3>Methods.—Radical Mastectomy (Mainly Stage I Clinically and Pathologically).—</h3> Radical mastectomy was performed when the primary lesion was located in the outer quadrants. If microscopic examination proved the axillary nodes to be free of metastases, no irradiation was given. <h3>Postoperative Irradiation (Mainly Stage II Clinically and Pathologically).—</h3> Radical mastectomy was followed by irradiation to the apex of the axilla, the supraclavicular region, and the internal mammary chain area in all patients with lesions in the outer quadrant accompanied by axillary nodal metastases, and in all patients with medially or centrally located lesions regardless of the status of the axillary nodes. <h3>Preoperative Irradiation (Mainly Stage III Clinically and Pathologically).—</h3> Preoperative irradiation followed by radical mastectomy was
THIRTY-SECOND ANNUAL MEETING OF THE MICHIGAN STATE MEDICAL SOCIETY.
Journal: JAMA (1897)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE NEW RULING ON PRESCRIPTIONS FOR LIQUOR
Journal: JAMA (1926)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Die Praxis der Hydrotherapie und verwasdter Hellmethoden.
Journal: JAMA (1910)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Tweeting Food-Borne Illness
Journal: JAMA (2014)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
BRONCHIECTASIS AND BRONCHITIS ASSOCIATED WITH ACCESSORY SINUS DISEASE
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
DOUBLE UTERUS
Authors: John J. Catlin
Journal: JAMA (1924)

Double uterus is a rather rare condition, but unless the possibility of such an abnormality is borne in mind, there is a chance that its occurrence will lead to mistake or difficulty in diagnosis, when with a normal organ there would be no difficulty. From recent literature, I have been able to find less than 150 reported cases. There are no doubt many more that have never been reported, and I can readily see how numerous others could exist without ever having been discovered. The condition is due to a lack of proper fusion, or to a lack of absorption of the fused walls of the ducts of Mueller, which normally unite to form vagina, uterus and tubes, at about the seventh or eighth week of uterine life. All degrees of malformation may occur, from a simple bicornate uterus to a complete double uterus, with two uterine canals, two cervices
The San Francisco Coroner.
Journal: JAMA (1889)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal