Heart Failure
Authors: Róisín Trainor, Eamon P. McCarron, Shiva Sreenivasan, Monica Monaghan
Journal: Annals of Internal Medicine (2018)

Letters20 November 2018Heart FailureRóisín Trainor, MB BCh, BAO, Eamon P. McCarron, MBChB (Hons), MPhil, Shiva Sreenivasan, MBBS(UWI), and Monica Monaghan, PhDRóisín Trainor, MB BCh, BAOSouth West Acute Hospital, Western Health and Social Care Trust, Enniskillen, United Kingdom (R.T., E.P.M., S.S., M.M.)Search for more papers by this author, Eamon P. McCarron, MBChB (Hons), MPhilSouth West Acute Hospital, Western Health and Social Care Trust, Enniskillen, United Kingdom (R.T., E.P.M., S.S., M.M.)Search for more papers by this author, Shiva Sreenivasan, MBBS(UWI)South West Acute Hospital, Western Health and Social Care Trust, Enniskillen, United Kingdom (R.T., E.P.M., S.S., M.M.)Search for more papers by this author, and Monica Monaghan, PhDSouth West Acute Hospital, Western Health and Social Care Trust, Enniskillen, United Kingdom (R.T., E.P.M., S.S., M.M.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/L18-0463 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Wu (1) provides a detailed review of current evidence on the prevention, diagnosis, and treatment of heart failure but does not consider the investigation and treatment of iron deficiency in chronic heart failure (CHF). Iron deficiency has been found in up to 50% of patients with CHF (2). It is associated with reduced functional capacity and an overall poorer quality of life (2).The FAIR-HF (Ferinject Assessment in Patients with Iron Deficiency and Chronic Heart Failure) and CONFIRM-HF (Ferric Carboxymaltose Evaluation on Performance in Patients with Iron Deficiency in Combination with Chronic Heart Failure) trials (3, 4) ...References1. Wu A. In the clinic - Heart failure. Ann Intern Med. 2018;168:ITC81-96. [PMID: 29868816]. doi:10.7326/AITC201806050 LinkGoogle Scholar2. Klip IT, Comin-Colet J, Voors AA, Ponikowski P, Enjuanes C, Banasiak W, et al. Iron deficiency in chronic heart failure: an international pooled analysis. Am Heart J. 2013;165:575-82. [PMID: 23537975] doi:10.1016/j.ahj.2013.01.017 CrossrefMedlineGoogle Scholar3. Anker SD, Comin Colet J, Filippatos G, Willenheimer R, Dickstein K, Drexler H, et al; FAIR-HF Trial Investigators. Ferric carboxymaltose in patients with heart failure and iron deficiency. N Engl J Med. 2009;361:2436-48. [PMID: 19920054] doi:10.1056/NEJMoa0908355 CrossrefMedlineGoogle Scholar4. Ponikowski P, van Veldhuisen DJ, Comin-Colet J, Ertl G, Komajda M, Mareev V, et al; CONFIRM-HF Investigators. Beneficial effects of long-term intravenous iron therapy with ferric carboxymaltose in patients with symptomatic heart failure and iron deficiency. Eur Heart J. 2015;36:657-68. [PMID: 25176939] doi:10.1093/eurheartj/ehu385 CrossrefMedlineGoogle Scholar5. Ponikowski P, Voors AA, Anker SD, Bueno H, Cleland JGF, Coats AJS, et al; ESC Scientific Document Group. 2016 ESC guidelines for the diagnosis and treatment of acute and chronic heart failure: the Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure of the European Society of Cardiology (ESC) developed with the special contribution of the Heart Failure Association (HFA) of the ESC. Eur Heart J. 2016;37:2129-200. [PMID: 27206819] doi:10.1093/eurheartj/ehw128 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: South West Acute Hospital, Western Health and Social Care Trust, Enniskillen, United Kingdom (R.T., E.P.M., S.S., M.M.)Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L18-0463. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoHeart Failure Audrey Wu Heart Failure Audrey Wu Metrics 20 November 2018Volume 169, Issue 10Page: 737-738KeywordsCongestive heart failureDisclosureExercise therapyHeartHeart diseasesHeart failureHospitalizationsIron deficiencyQuality of lifeSerum ferritin levels ePublished: 20 November 2018 Issue Published: 20 November 2018 Copyright & PermissionsCopyright © 2018 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...