tbuckley/cabot-search huggingface dataset:
Medical schools in Canada
Journal: JAMA (1996)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Dermal Elastoses
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Coombs' (antiglobulin) test
Authors: J. R. Bove
Journal: JAMA (1967)

The detection of antibodies against human erythrocytes is important in the diagnosis of hemolytic anemia, erythroblastosis fetalis, and transfusion reactions and is essential for crossmatching blood before transfusion. Such antibodies belong to the immunoglobulin group of proteins. The immunoglobulin-S are IgG, the most common; IgM; and IgA. Tests for blood group antibodies must detect antibody protein of all three immunoglobulin types. While no one test will do this for every antibody, the Coombs' (antiglobulin) test is the best because it reacts with most antibodies in each class of immunoglobulin. The test is done with antiglobulin serum, an anti-antibody type of reagent produced in laboratory animals. Rabbits injected with human serum produce antibodies to human proteins. Serum from such immunized animals, when properly prepared, can be used as an anti-antibody to detect human immunoglobulins, particularly those that have reacted with erythrocytes. In the Coombs' test, erythrocytes coated with antibody are agglutinated
Molecular Electrostatic Potentials: An Effective Tool for the Elucidation of Biochemical Phenomena
Authors: Peter Politzer, Patricia R. Laurence, Keerthi Jayasuriya
Journal: Environmental Health Perspectives (1985)

The electrostatic potential V(r) that is created in the space around a molecule by its nuclei and electrons (treated as static distributions of charge) is a very useful property for analyzing and predicting molecular reactive behavior. It is rigorously defined and can be determined experimentally as well as computationally. The potential has been particularly useful as an indicator of the sites or regions of a molecule to which an approaching electrophile is initially attracted, and it has also been applied successfully to the study of interactions that involve a certain optimum relative orientation of the reactants, such as between a drug and its cellular receptor. A variety of methods for calculating V(r) is available, at different levels of rigor. For large biologically active molecules, multipole expansions and superposition of potentials computed for subunits have been found to be effective. A large number of chemical and biochemical systems and processes have now been studied in terms of electrostatic potentials. Three examples of such applications are surveyed in this paper. These deal with: (a) reactive properties of nucleic acids, including their component bases; (b) biological recognition processes, including drug-receptors and enzyme-substrate interactions; and (c) chemical carcinogenesis, referring specifically to the polycyclic aromatic hydrocarbons and halogenated olefins and their epoxides. For each of these areas, examples of the use of electrostatic potentials in elucidating structure-activity patterns are given.
Impact d'un régime alimentaire à faible teneur en résidus d'une journée ou de trois jours sur la qualité du nettoyage de l'intestin avant la coloscopie: un essai contrôlé randomisé
Journal: Endoscopy (2019)

La préparation colique est un critère fondamental de qualité de la coloscopie. Une préparation en deux prises, et un délai minimal entre la dernière prise de préparation et la coloscopie sont recommandés. Un régime sans résidu (RSR) la veille de la préparation est également préconisé par la société européenne d’endoscopie digestive (ESGE), sans pour autant avoir jusqu’ici un niveau de preuve élevé dans la littérature, conduisant ainsi de nombreux endoscopistes à proposer des RSR de 2 à 3 jours.
From the Centers for Disease Control and Prevention. Evaluation of surveillance for Chlamydia trachomatis infections in the United States, 1987 to 1991
Journal: JAMA (1993)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Antiviral Drugs
Authors: Henry H. Balfour
Journal: New England Journal of Medicine (1999)

Eleven drugs approved by the Food and Drug Administration for the treatment of viral infections (other than those caused by human immunodeficiency virus type 1 [HIV-1] or those complicating such infection) will be reviewed in this article. They are seven nucleoside analogues, two closely related 10-carbon-ring amines, one pyrophosphate analogue, and a recombinant protein produced in bacteria (Figure 1). The characteristics of these antiviral drugs are given in Table 1, management of their adverse effects is outlined in Table 2, and specific recommendations for their use are provided in Table 3.Approved DrugsAcyclovirAcyclovir is an analogue of 2'-deoxyguanosine that exerts its . . .
MOSCOW
Journal: JAMA (1934)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Postnatal depression: does no one care?
Authors: C Kenneth
Journal: BMJ (1980)

SIR,-With reference to the article "Postnatal depression: does no one care ?" (8 December, p 1487), I would like to point out that the subject of postpartum psychiatric disorders has been scrutinised and been the subject of a lot of time and energy of many researchers for over a century.'Needless to say, numerous papers and research projects have been published during this time.These concern many aspects of the whole spectrum of these disorders-from acute psychotic disorders2 to the "three-day blues syndrome,"'3 including postpartum depression.4With this history in mind I would like to reassure the author that the lack of "appropriate hormones" to treat people like his wife is not the result of people "not having a care" to answer the queries he poses but is much more likely to be a direct reflection of the complexity of the biochemical and endo- crinological state of the psychiatrically ill puerperal women.As far as the "lack of warning" that patients will be affected is concerned, epidemiological studies and research into the aetiology of these disorders are plentiful5 7 and concern in this respect is in an ever-evolving state.
Prevalence of Elevated Blood Lead Levels in an Inner-City Pediatric Clinic Population
Authors: Shoshana T. Melman, Joseph W. Nimeh, Ran D. Anbar
Journal: Environmental Health Perspectives (1998)

For a cohort of 1189 male German former herbicide and insecticide workers with exposure to polychlorinated dibenzo-p-dioxins and -furans (PCDD/F), we report an extended standardized mortality ratio (SMR) analysis based on a new quantitative exposure index. This index characterizes the cumulative lifetime exposure by integrating the estimated concentration of PCDD/F at every point in time (area under the curve). Production department-specific dose rates were derived from blood levels and working histories of 275 workers by applying a first-order kinetic model. These dose rates were used to estimate exposure levels for all cohort members. Total mortality was elevated in the cohort; 413 deaths yielded an SMR of 1.15 (95% confidence interval [Cl] 1.05, 1.27) compared to the mortality of the population of Germany. Overall cancer mortality (n = 124) was significantly increased (SMR = 1.41, 95% Cl 1.17, 1.68). Various cancer sites showed significantly increased SMRs. The exposure index was used for an SMR analysis of total cancer mortality by dose. For 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) a significant trend (p = 0.01) for the SMRs with increasing cumulative PCDD/F exposure was observed. The SMR in the first exposure quartile (0-125.2 ng/kg x years) was 1.24 (95% Cl 0.82, 1.79), increasing to 1.73 (95% Cl 1.21, 2.40) in the last quartile (> or = 2503.0 ng/kg x years). For all congeners combined as toxic equivalencies (TEQ) using international toxic equivalency factors, a significant increase in cancer mortality was observed in the second quartile (360.9-1614.4 ng/kg x years, SMR 1.64; 95% Cl 1.13, 2.29) and the fourth quartile (> or = 5217.7 ng/kg x years TEQ, SMR 1.64, 95% Cl 1.13, 2.29). The trend test was not significant. The results justify the use of this cohort for a quantitative risk assessment for TCDD and to a lesser extent for TEQ.
A Developmental fMRI Study of Self-Regulatory Control in Tourette’s Syndrome
Authors: Rachel Marsh
Journal: American Journal of Psychiatry (2007)

Objective: Disturbances in the maturation of neural systems that mediate self-regulatory processes may contribute to the development of Tourette’s syndrome by releasing motor and vocal tics from regulatory control. The purpose of this study was to examine the age correlates of functional activity in neural circuits that subserve self-regulatory control in children and adults with Tourette’s syndrome. Method: The participants were 136 children and adults, which included 66 Tourette’s syndrome patients and 70 healthy comparison subjects. During performance of the Stroop interference task, the authors compared the functional magnetic resonance imaging (fMRI) blood-oxygen-level dependent response in patients with Tourette’s syndrome with that of healthy comparison subjects. General linear modeling of Stroop-related activations was used to compare the differential effects of age and behavioral performance on changes in self-regulatory control between the two diagnostic groups. Results: Although the correlations of age with behavioral performance on the Stroop task were similar between patients with Tourette’s syndrome and healthy comparison subjects, the two groups differed significantly in their correlations of age with the magnitude of regional brain activation during the task. Interactions of age with diagnosis were detected in the ventral prefrontal (Brodmann’s areas 10 and 24) and posterior cingulate cortices (Brodmann’s area 31), and post hoc analyses indicated that subjects with Tourette’s syndrome deactivated these regions less with advancing age. Greater activation of bilateral frontostriatal regions (Brodmann’s areas 9/46, 45/46; lenticular nucleus; and thalamus) accompanied poorer performance in the patient group, which—in the presence of normal behavioral performance on the Stroop task—suggests that greater activation of the frontostriatal systems helps to maintain task performance in individuals with Tourette’s syndrome. Conclusions: Normative developmental correlates of activity in frontostriatal circuits that subserve self-regulatory control are disturbed in persons with Tourette’s syndrome. These aberrant developmental correlates are likely a consequence of greater anatomical and functional disturbances in these circuits in adults with Tourette’s syndrome, which leads to impaired regulation of tic behaviors. Reduced default-mode processing in ventral prefrontal and posterior cingulate cortices in adults with Tourette’s syndrome suggests the presence of greater difficulty in engaging mental processes that become active when freed from the demands of more challenging cognitive tasks. However, individuals with Tourette’s syndrome appear to co-opt normal developmental processes in circuits that subserve age-related improvement in self-regulatory control while presumably struggling to maintain adequate task performance.
Sixth Annual Report of the State Board of Health of the State of Connecticut, for the fiscal year ending November 30, 1883.
Authors: None C. E. W.
Journal: JAMA (1885)

The first fifty pages of the volume present the general report. This consists of a discussion of the practical benefits of sanitary enactments, a review of the diseases generally regarded as infectious or contagious, followed by a consideration of the various special subjects coming under the department of State Hygiene. Among the various papers that make up the body of the work is one on the sanitary drainage of tenement houses. This paper is clear and explicit in its style and illustrated by numerous cuts. The concluding pages are occupied by the registration report of the Bureau of Vital Statistics.
Systemic Lupus Erythematosus with Erythermalgia
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Decitabine Low-Dose Schedule (100 mg/m2/Course) in Myelodysplastic Syndrome (MDS). Comparison of 3 Different Dose Schedules.
Authors: Hagop Kantarjian, Susan O’Brien, Francis Giles, Farhad Ravandi-Kashani, Stefan Faderl, Guillermo Garcia-Manero, Jan Davis, Jean-Pierre Issa
Journal: Blood (2005)
Old Age—Medically Considered
Journal: JAMA (1935)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Endocrine Society Awards
Journal: Endocrine Reviews (1996)

RECIPIENTS of the Awards of The Endocrine Society are selected by the Awards Committee. The Endocrine Society Awards may be made to endocrinologists, members or non-members, from anywhere in the world. Nominations may be made by Society members only. A complete listing of all past Awardees is in the Membership Directory of The Endocrine Society.
Dermatology—More Than Skin Deep
Authors: Zenonas Danilevicius
Journal: JAMA (1977)

Research in immunobiology, immunopathology, and immunochemistry has left deep impressions on many of the clinical disciplines. Although tissue and organ transplantation is in the field of surgery, it is tied in deeply with immunological phenomena, especially the graft-vs-host reaction. Changing the patient's immunological status exposes the patient to opportunistic, previously unknown infections. The resistance to various diseases or lack of it is now explained by immunological factors and conditions. The skin, being a large, important, and more exposed organ than others of the body, depends to a high degree on various immunological changes, degrees of immunity, and the body's own immunological defenses. Some authors have even created a new term, "immunodermatology," which actually describes the interrelation between immunological phenomena and dermatological conditions and their treatment or prevention. Recently, K. Frank Austen and other prominent immunologists and dermatologists prepared a special issue of<i>The Journal of Investigative Dermatology</i>(September 1976). The
The Lettsomian Lectures on Syphilis and the Nervous System
Authors: W. R. Gowers
Journal: BMJ (1889)

PRESIDENT AND GENTLEMEN,-From the questions of pathology and causal evidence that occupied us in the last lecture, we pass to-night to the subjects of more immediate practical interest -those of symptoms and diagnosis.The transition may, perhaps, bring with it a sense of relief, but, unfortunately, it brings with it no escape from the difficulties in which the subject is involved, and which surround, not less closely and scarcely less consciously, its practical aspects.First, however, I should supply one omission injthe last lecture.To the long list of maladies, the certain or suipposed consequences of syphilis, slhould be added some of the functional diseases of the nervous system.By some authorities it is thought that such diseases as epilepsy, lhysteria, insanity, and neuralgia, in their purely functional forms, are frequient consequences of the influ- ence of the virus on the nerve-elements during the period of its greatest activity.Time fails me for any discussion of the subject, but there are two points that are especially important in any ex- amination of the subject.The first is that if any special form of functional disease seems to be exclusively related to syphilis, it is
Processes Affecting the Remediation of Chromium-Contaminated Sites
Authors: Carl D. Palmer, Paul R. Wittbrodt
Journal: Environmental Health Perspectives (1991)

The remediation of chromium-contaminated sites requires knowledge of the processes that control the migration and transformation of chromium. Advection, dispersion, and diffusion are physical processes affecting the rate at which contaminants can migrate in the subsurface. Heterogeneity is an important factor that affects the contribution of each of these mechanisms to the migration of chromium-laden waters. Redox reactions, chemical speciation, adsorption/desorption phenomena, and precipitation/dissolution reactions control the transformation and mobility of chromium. The reduction of CrVI to CrIII can occur in the presence of ferrous iron in solution or in mineral phases, reduced sulfur compounds, or soil organic matter. At neutral to alkaline pH, the CrIII precipitates as amorphous hydroxides or forms complexes with organic matter. CrIII is oxidized by manganese dioxide, a common mineral found in many soils. Solid-phase precipitates of hexavalent chromium such as barium chromate can serve either as sources or sinks for CrVI. Adsorption of CrVI in soils increases with decreasing chromium concentration, making it more difficult to remove the chromium as the concentration decreases during pump-and-treat remediation. Knowledge of these chemical and physical processes is important in developing and selecting effective, cost-efficient remediation designs for chromium-contaminated sites.
Etanercept Plus Methylprednisolone as Initial Therapy for Acute GVHD.
Authors: John E. Levine, Sophie Paczesny, Shin Mineishi, Thomas Braun, Sung W. Choi, Raymond J. Hutchinson, Dawn Jones, Yasser Khaled, Carrie Kitko, Oleg Krijanovski, Pavan Reddy, Gregory Yanik, James L.M. Ferrara
Journal: Blood (2007)