tbuckley/cabot-search huggingface dataset:
A MAINTENANCE DIET FOR DIABETICS
Journal: JAMA (1918)

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Rheumatic Diseases Based on the Proceedings of the Seventh International Congress on Rheumatic Diseases
Journal: JAMA (1952)

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Commentary
Journal: JAMA (1964)

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Antibiotic Breakpoints
Authors: Mike Mitka
Journal: JAMA (2012)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Is there a higher prevalence of methicillin-resistant Staphylococcus aureus (MRSA) or vancomycin-resistant Enterococcus (VRE)colonization in patients with antibiotic allergies?
Authors: Weyman Lam, Mary L. Staicu, Kelly M. Conn, Allison Ramsey
Journal: Journal of Allergy and Clinical Immunology (2018)
Scientific Forum Analyzes Programming Problems
Journal: JAMA (1964)

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The Cambridge Diet
Authors: A. N. Howard
Journal: JAMA (1984)

<h3>In Reply.—</h3> Dr Howard's letter is not responsive to our criticisms of the Cambridge Diet. We made no claim that the diet "is fundamentally unsafe." In fact, we specifically noted that it "may not be inherently dangerous" but that "danger arises from the manner in which the diet is used." A major problem with the Cambridge Diet that we addressed is the manner in which it is marketed to the public—without assurance that its users will obtain the close medical supervision that is required with all very-low-calorie diets.<sup>1</sup> Dr Howard contends, on the basis of survey data and data from the FDA, that the Cambridge Diet is safe. This contention rests on the assumption that there has been a complete reporting of all deaths associated with the diet—a very risky assumption. It is precisely the manner in which the diet is marketed that prevents Cambridge International from obtaining accurate
Lactic Acidosis Traced to Thiamine Deficiency Related to Nationwide Shortage of Multivitamins for Total Parenteral Nutrition—United States, 1997
Journal: JAMA (1997)

Since November 1996, there has been a nationwide shortage of intravenous (IV) multivitamins (MVIs) used in U.S. hospitals and home-health-care agencies for total parenteral nutrition (TPN). Patients receiving TPN without MVI supplementation are at risk for thiamine deficiency and life-threatening complications associated with severe deficiency of thiamine, a coenzyme necessary for oxidation of keto acids (Figure 1). This report describes three patients receiving TPN who had thiamine deficiency-related lactic acidosis in 1997 and presents recommendations for alternatives to parenteral MVI during the shortage.
Medical Education, Registration and hospital Service
Journal: JAMA (1924)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
DEATHS
Journal: JAMA (1953)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 2961: Ganoderma lucidum extracts inhibit mTORC1/2 by activating AMPK and inhibiting IGFR/PI3K/Rheb in tumor cells
Authors: Shile Huang, Didem Sohretoglu, Chao Zhang, Jun Luo
Journal: Cancer Research (2019)

Abstract Ganoderma lucidum (G. lucidum) extracts, as dietary supplements, have been found to possess potent anticancer activity, which is attributed to the presence of polysaccharides and triterpenes. However, the molecular mechanism underlying the anticancer action of G. lucidum extracts remains to be elucidated. Here we show that ReishiMax GLp, containing both polysaccharides and triterpenes of G. lucidum (GLPT), inhibited cell proliferation and induced cell death in human lung cancer cells (A549 and A427), and concurrently suppressed the signaling pathways mediated by the mammalian target of rapamycin (mTOR), a central regulator of cell proliferation and survival. Interestingly, GLPT not only inhibited mTORC1-mediated phosphorylation of p70 S6 kinase 1 (S6K1) and eukaryotic initiation factor 4E binding protein 1 (4E-BP1), but also repressed mTORC2-mediated phosphorylation of Akt. Mechanistically, GLPT downregulated the phosphorylation and protein levels of insulin-like growth factor 1 receptor (IGFR) and phosphoinositide 3-kinase (PI3K), as well as the protein level of RAS homolog enriched in brain (Rheb). Besides, GLPT also activated AMP-activated protein kinase (AMPK) network. This is supported by the findings that GLPT increased the phosphorylation of AMPKα (T172), as well as its substrates tuberous sclerosis complex 2 (TSC2, S1387) and regulatory-associated protein of mTOR (raptor, S792). Ectopic expression of dominant negative AMPKα partially attenuated the inhibitory effect of GLPT on mTORC1, indicating that GLPT inhibits mTORC1 partly via activating AMPK. The results suggest that G. lucidum extracts execute the anticancer action at least partly by inhibiting the mTORC1/2 signaling through activation of AMPK and inhibition of IGFR/PI3K/Rheb in tumor cells. Supported by the Feist-Weiller Cancer Center, LSU Health Sciences Center, Shreveport, LA, USA. Citation Format: Shile Huang, Didem Sohretoglu, Chao Zhang, Jun Luo. Ganoderma lucidum extracts inhibit mTORC1/2 by activating AMPK and inhibiting IGFR/PI3K/Rheb in tumor cells [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 2961.
Endotracheal intubation in the prehospital phase of emergency medical care
Authors: L. M. Jacobs
Journal: JAMA (1983)

One hundred seventy-eight endotracheal intubations by paramedics were reviewed prospectively during a nine-month period; 149 patients (83.7%) had medical conditions, and 29 (16.2%) had trauma. The endotracheal tube was successfully placed in 172 (96.6%); in four patients (2.2%), attempts were unsuccessful, and in two patients (1.1%), the attempt was aborted. There were no incidences of reported complications. We conclude that endotracheal intubation can be accomplished successfully outside the hospital by paramedical personnel. Comprehensive training and continuous medical control of paramedics' activities seem to be essential requirements for its success. (<i>JAMA</i>1983;250:2175-2177)
THE NEUROCHEMISTRY OF FITS
Journal: JAMA (1960)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Minerva Cardioangiologica, Turin
Journal: JAMA (1964)

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Table of Contents
Authors: Efthymia Soura, Philip Eliades, Kristen Shannon, Alexander Stratigos, Hensin Tsao, Katherine Ransohoff, Prajaka Jaju, Jean Tang, Michele Carbone, Sancy Leachman, Kavita Sarin, Prajakta Jaju, Shelley Ji, Eun Hwang, Giuliana Carlos, Deepal Wakade, Karen Byth, Benjamin Kong, Shaun Chou, Matteo Carlino, Richard Kefford, Pablo Fernandez-Penas, Jamie Hanson, Jaime Kingsley-Loso, Katherine Grey, Srihari Raju, Patricia Parks, Andrea Bershow, Erin Warshaw, Joshua Schulman, Mariela Pauli, Isaac Neuhaus, Roberto Sanchez Rodriguez, Keyon Taravati, Uk Shin, Timothy Mccalmont, Michael Rosenblum, Elyse Love, Iviensan Manalo, Suephy Chen, Kuang-Ho Chen, Benjamin Stoff, Caroline Nelson, Junko Takeshita, Karolyn Wanat, Kent Bream, John Holmes, Helen Koenig, Rudolf Roth, Anitha Vuppalapati, William James, Carrie Kovarik, Wenxin Yu, Gang Ma, Yajing Qiu, Hui Chen, Yunbo Jin, Xi Yang, Xiaojie Hu, Tianyou Wang, Lei Chang, Henghua Zhou, Wei Li, Xiaoxi Lin, Angel Fernandez-Flores, Jose´luis Rodriguez-Peralto, Reva Bhushan, Mark Lebwohl, Alice Gottlieb, Kevin Boyer, Elaine Hamarstrom, Neil Korman, Robert Kirsner, Arthur Sober, Alan Menter, Lauren Metterle, Christopher Nelson, Nishit Patel, Ann John, Robert Schwartz, Markus Boos, Leslie Castelo-Soccio, Blanca De, Unamuno Bustos, Rosa Estal, Gema Simo´, Vicente Martı ´nez, Margarita Ros, Sarai Palanca Suela, Rafael Estrada, Pierre-Alexandre Just, Christelle Pouliquen, Anne Audebourg, Sara Laurent-Roussel, Agne `s Carlotti, Nicolas Dupin, Marie-Ce´cile Vacher-Lavenu, Michel Vidaud, ˆt Terris, Eric Pasmant
Journal: Journal of the American Academy of Dermatology (2016)
What's hot that the other lot got
Authors: Kathryn Prior
Journal: Thorax (2016)

ARDSLUNG SAFE study was an international, multi-centre, prospective cohort study of patients undergoing invasive or noninvasive ventilation who were admitted to 459 intensive care units (ICU) for 4 consecutive weeks in the northern hemisphere winter of 2014 in 50 countries (doi: 10.
Ankylosing spondylitis in a black woman. Association with HL-A W-27
Authors: B. W. Myers
Journal: JAMA (1975)

ANKYLOSING spondylitis (AS) has recently been associated with the W27 tissue antigen in an incidence of 88% to 96%, as compared to 4% to 9% of controls.<sup>1,2</sup>The disease is more prevalent in men than in women, the incidence being 0.4% in men and 0.05% in women.<sup>2</sup>Baum and Ziff<sup>3</sup>have previously described the rarity of AS among blacks and concluded that the incidence in black men was 25% that in white men. Swezey and his colleagues<sup>4</sup>have commented on a lower prevalence of HL-A W27 in black women with AS. We report a black woman (Fig 1) who does have the W27 antigen and well-demonstrated spondylitis. <h3>Report of a Case</h3> A 30-year-old black female nurse had had intermittent lumbosacral pain four years before admission. Two years before admission, neck pain developed and she was seen by an orthopedist for acute arthritis of the right sternoclavicular
Diseases of the Skin.
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 19772: The Significance of Blood Pressure on Cardiovascular Risk Attributable to Diabetes
Authors: Ryosuke Komi, Fumitaka Tanaka, Shinji Makita, Toshiyuki Onoda, Kozo Tanno, Masaki Ohsawa, Kazuyoshi Itai, Kiyomi Sakata, Shin-iti Omama, Kuniaki Ogasawara, Yasuhiro Ishibashi, Akira Okayama, Motoyuki Nakamura
Journal: Circulation (2014)

Background: Diabetes mellitus (DM) is an established risk factor of atherosclerotic cardiovascular events (CVE). Individuals with DM often have elevated levels of blood pressure (BP) which is closely associated with CVE. Hypothesis: The risk of DM-related CVE may depend on BP levels. Methods: A population-based prospective cohort study was performed in 24,350 subjects aged 40 to 89 years (mean age = 63.0±10.0 years) who did not have a history of CVE. DM was defined as a casual blood glucose level ≥ 200 mg/dl or fasting blood glucose level ≥ 126 mg/dl, a glycated hemoglobin value ≥ 6.5%, and/or current anti-diabetic therapy. BP levels at the baseline examination were classified into three categories including normotension, pre-hypertension, and hypertension according to JNC7. This classification was applied also to subjects with antihypertensive agents use. After adjustment for age, sex, body mass index, eGFR, total and HDL cholesterol, smoking habits, and anti-hypertensive medication use, a multivariate Cox regression analysis was performed to examine an association and contribution of pre-hypertension and hypertension on the risk of CVE in DM and non DM. Results: During a mean follow-up period of 5.5 years, 746 subjects developed CVE which was defined as stroke or acute myocardial infarction/sudden cardiac death. In both DM and non DM, the hazard ratios for CVE were increased in pre-hypertensives (HR 1.25, p &lt; 0.05; HR 2.59, p &lt; 0.02, respectively) and in hypertensives (HR 1.82, p &lt; 0.01; HR 3.66, p &lt; 0.01, respectively) in comparison with normotensives. However, the population-attributable fractions (PAFs) of pre-hypertension and hypertension were apparently higher in DM (21.5%, 41.2%, respectively), as these were more than double compared to PAFs in non DM (6.7%, 20.3%, respectively). Conclusions: Approximately two-third of excess CVE attributable to DM is estimated to occur among individuals with elevated BP levels.
Real-Time Quantitative Polymerase Chain Reaction (RQ-PCR) On Peripheral Blood (PB) and Bone Marrow (BM) Samples for Monitoring Minimal Residual Disease (MRD) in Patients (pts) with Acute Promyelocytic Leukemia (APL) Treated with All-Trans-Retinoic Acid (ATRA) and Arsenic Trioxide (ATO).
Authors: Hady Ghanem, Hagop M. Kantarjian, Stefan Faderl, Elias J. Jabbour, Naval Daver, Sherry A. Pierce, Mark Brandt, Alfonso Quintás-Cardama, Rajyalakshmi Luthra, Guillermo Garcia-Manero, Jorge E. Cortes, Farhad Ravandi
Journal: Blood (2012)