tbuckley/cabot-search huggingface dataset:
LETTER FROM LONDON.
Authors: None G. O. M.
Journal: JAMA (1890)

(FROM OUR OWN CORRESPONDENT.) England as a Health Resort—Pasteur on Influenza—Specimen of a Cardiolith—Agaricin—Surgeon LeQuesne—George Moore, M.D. Invalids who frequent foreign health resorts, and in winter flock in great numbers to Southern France or Northern Italy, do not seem to be aware that resources are presented in this respect by England. At the present time many people are singing the praises of Cornwall as a winter resort for delicate persons, and a considerable amount of useful and interesting information is to be found in a pamphlet which has recently been issued. Many long years ago the wellknown writer, Dr. Paris, called attention to a good many things that appear to be more or less forgotten now, and crop up again as novelties until critics have shown that they were already known. It is sixty years ago that Dr. Paris wrote to the effect that " the very coldest parts of England
MEDICAL ECONOMIC REVIEWS AND ABSTRACTS
Journal: JAMA (1949)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Inflammatory oncotaxis
Authors: R. P. DerHagopian
Journal: JAMA (1978)

Tumor recurrence after a prolonged disease-free interval suggests that neoplastic cells may remain dormant within the host. Activation and growth of these metastatic focuses may occur secondary to inflammation at sites distant from the primary tumor. The concept of inflammatory oncotaxis is presented as a mechanism of cancer cell attraction and facilitation of transcapillary migration into tissue spaces. Physicians should focus astutely on internal and external sites of inflammation as possible focuses for tumor recurrence in the follow-up of the cancer patient. (<i>JAMA</i>240:374-375, 1978)
DRES-20. THE TNF RECEPTOR FAMILY MEMBER Fn14 IS HIGHLY EXPRESSED IN RECURRENT GLIOBLASTOMA (GBM) AND IN GBM PATIENT-DERIVED XENOGRAFTS WITH ACQUIRED TEMOZOLOMIDE RESISTANCE
Authors: David Hersh, Jonathan Heath, Graeme Woodworth, Nhan Tran, Jeffrey Winkles
Journal: Neuro-Oncology (2018)

The current standard-of-care for patients with glioblastoma (GBM) consists of maximal safe surgical resection followed by high-dose radiation and concomitant oral chemotherapy using the DNA-alkylating agent temozolomide (TMZ). Despite this combination treatment, tumor recurrence is nearly universal. Recurrent GBM tumors tend to be more aggressive and treatment-resistant than their primary (i.e. newly diagnosed) counterparts. A better understanding of recurrent GBM biology would offer new opportunities for tailoring treatments following standard-of-care chemo-radiation therapy. Our prior work has demonstrated an important role for the TWEAK receptor Fn14 in GBM patho-biology. In the current study, we investigated Fn14 expression in recurrent GBM and in the setting of TMZ resistance. Fn14 mRNA expression levels in non-neoplastic brain, primary GBM, and recurrent GBM (post-chemotherapy and radiation) specimens were obtained from the TCGA data portal. Immunohistochemistry was performed using non-neoplastic brain as well as patient-matched primary and recurrent GBM specimens to examine Fn14 protein levels. Western blot analysis was used to compare Fn14 expression in parental TMZ-sensitive or matched TMZ-resistant patient-derived xenografts (PDXs) established from primary or recurrent tumor samples. The migratory capacity of control and Fn14-depleted TMZ-resistant GBM cells was assessed using the transwell migration assay. We found that Fn14 is more highly expressed in recurrent GBM tumors than their matched primary GBM counterparts. GBM PDX cells with acquired TMZ resistance have higher Fn14 levels and greater migration capacity than their corresponding parental TMZ-sensitive cells, and the migratory difference is due, at least in part, to Fn14 expression in the TMZ-resistant cells. CONCLUSIONS: This study demonstrates that the Fn14 gene is highly expressed in recurrent GBM and TMZ-resistant GBM PDX tumors. These findings suggest that Fn14 may be a valuable therapeutic target or drug delivery portal for treatment of recurrent GBM patients.
Erratum
Journal: BMJ (1898)

ALPHA.-SO far as we are aware, there is no other society of the kind in existence.F.R.C.S.-The secret nostrums of quacks can only be treated as abomina- tions to be avoided.The particular one referred to-judging from its designation-is probably one of the class containing large doses of potassium iodide, which would in some instances be dangerous.INQtIRENS.-Tfour correspondent will refer to the BRITISH MEDICAL JOURNAL of Decemiber 25th, I897, p. i888, he will find a statement to the effect that the " Omega" stove is a portable one, and that the arrange- ment described is such that the products of combustion enter the room.He will further find that "we do not feel justified in recommending any stove for use in a living room which does not remove the products of combustion, however applicable such stoves may be for shops, halls, lobbies, and wine celJars."HOME FOR INEBRIATES.
Advancing HIV Prevention: New Strategies for a Changing Epidemic—United States, 2003
Journal: JAMA (2003)

In several U.S. cities, recent outbreaks of primary and secondary syphilis among men who have sex with men (MSM) and increases in newly diagnosed human immunodeficiency virus (HIV) infections among MSM and among heterosexuals have created concern that HIV incidence might be increasing. In addition, declines in HIV morbidity and mortality during the late 1990s attributable to combination antiretroviral therapy appear to have ended. Until now, CDC has mainly targeted its prevention efforts at persons at risk for becoming infected with HIV by providing funding to state and local health departments and nongovernmental community-based organizations (CBOs) for programs aimed at reducing sexual and drug-using risk behavior. Some recent programs have focused on prevention efforts for persons living with HIV. Funding HIV-prevention programs for communities heavily affected by HIV has promoted community support for prevention activities. At the same time, these communities recognize the need for new strategies for combating the epidemic. In addition, the recent approval of a simple rapid HIV test in the United States creates an opportunity to overcome some of the traditional barriers to early diagnosis and treatment of infected persons. Therefore, CDC, in partnership with other U.S. Department of Health and Services agencies and other government agencies and nongovernment agencies will launch a new initiative in 2003, Advancing HIV Prevention: New Strategies for a Changing Epidemic.
EMBRYOLOGY AND ATHEROSCLEROSIS
Journal: JAMA (1962)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
AMA-RPS Adopts Medical Education Policy
Journal: JAMA (1995)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
What is role of Factor VIII therapy in inducing helper suppressor ratio reversals in hemophiliacs?
Journal: JAMA (1983)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
APPENDICITIS
Journal: JAMA (1962)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Unfounded Worries about Cancer in Patients Attending a Routine Otolaryngology Clinic
Authors: Safina Ali, B J G Bingham
Journal: Journal of the Royal Society of Medicine (2005)

To investigate a suspicion that many ear, nose and throat patients have unfounded concerns about cancer, we questioned 50 patients who had attended a routine clinic after screening-out of those with possibly cancer-related features. None of the 50 proved to have cancer. 15 (30%) had been worried about cancer and 7 of these were still worried despite the consultation. Unwarranted fears about cancer are best dealt with by the referring clinician, especially when the wait for an appointment will be long. Such fears also need to be recognized and addressed by the specialist.
Anomalia May-Hegglin: Affection Hereditari de Granulocytos e de Thrombocytos
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Pseudomonas septicaemia.
Authors: D A Hopkin
Journal: BMJ (1980)

nervosa.She was subject to recurrent hypoglycaemia and on one occasion had a grand mal fit.After a joint medicopsychiatric admission she was followed up in both clinics in conjunction.She remained at about 42 kg (standard 50 kg) until just after taking 0 levels at 16; she lost 4 kg in a few weeks, and was subsequently found dead in bed.A few missed periods and fluctuations in weight are commonplace in adolescence.Primary anorexia nervosa is liable to arise when lack of menses and weight loss come specifically to assuage high levels of adolescent anxiety.The combination of the illusion of self control, the safety of emotional regression, -and reaffirmation of parental concern may be rewarding enough to maintain and intensify weight-reducing behaviour.In our second patient the strains of puberty and adolescence were added to the psychological disturbance common in unstable diabetes3-leading to overdose, wristcutting, and finally anorexia nervosa.The reason for her death was un- certain but she did not have autonomic neuropathy, which can predispose to cardio- respiratory arrest in diabetes.4It seems that the association between anorexia nervosa and diabetes mellitus is neither excessively rare nor particularly common, but what would be expected by chance.However, since the secondary forms of anorexia nervosa merge into various neurotic reactions it is probable that a search among diabetics would produce an appreciable number with neurotic be- haviour which included an obsession with weight.
THE CHAIRMAN'S ADDRESS IN STOMATOLOGY.
Journal: JAMA (1902)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Laser treatment of tattoos. A preliminary survey of three year's clinical experience
Authors: L. Goldman
Journal: JAMA (1967)

Preliminary experiences with lasers in the treatment of tattoos over a period of more than three years have shown that this is a safe procedure, both for the patient and for the operating personnel, when conducted in specially designed laboratories and with planned safety programs. The laser treatment of tattoos is still, and will continue to be for some time, an investigative treatment and not a conventional treatment.
Cardiovascular hemodynamics. Determination from the distribution of pulmonary blood flow in seated patients
Authors: S. H. Steiner
Journal: JAMA (1968)

Iodinated I 131 serum albumin aggregated, when injected intravenously into seated patients, affords an accurate measurement of certain hemodynamic indices. In patients with mitral stenosis, the ratio of distribution of this drug in the upper and middle portions of the lungs correlates well with pulmonary arterial and left atrial pressures and inversely with cardiac output. The presence of idiopathic pulmonary hypertension, but not its severity, can be determined, since the flow distribution pattern becomes relatively uniform despite a wide pressure range. The method has considerable advantage over the radioactive gas techniques with oxygen 15, krypton 85, and xenon 133, since the radioactive serum albumin is more easily handled and has only arterial distribution without an alveolar gas phase. Caution should be exercised in relying completely upon the results of the lung scans and ratios where emphysema, congestive heart failure, and pulmonary emboli concomitantly exist.
Erratum for the Research Article: “Targeting KRAS-dependent tumors with AZD4785, a high-affinity therapeutic antisense oligonucleotide inhibitor of KRAS” by S. J. Ross, A. S. Revenko, L. L. Hanson, R. Ellston, A. Staniszewska, N. Whalley, S. K. Pandey, M. Revill, C. Rooney, L. K. Buckett, S. K. Klein, K. Hudson, B. P. Monia, M. Zinda, D. C. Blakey, P. D. Lyne, A. R. Macleod
Journal: Science Translational Medicine (2017)
Section 1.—Introduction
Journal: JAMA (1973)

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Reports on Sanitary Engineering in Houses, Hospitals, and Public Institutions
Authors: W. Eassie
Journal: BMJ (1873)

WITHIN the last few years considerable attention has been directed to the treatment of the excreta at the moment that theyare being delivered to the drain, and it has resolved itself either into the distributing over the soil of a certain portion of smell-arresting powder, or the injecting into the closet basin a quantity of deodorising fluid.Unquestionably, by such means, the air of the closet room is rendered less offensive, but whether the faeces are disinfected and rendered innocuous or
Official Warning Against Charlatans.
Journal: JAMA (2003)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal