tbuckley/cabot-search huggingface dataset:
Detection of hepatitis C virus with RNA polymerase chain reaction in fulminant hepatic failure
Authors: Federico G. Villamil, Ke-Qin Hu, Chang-Hong Yu, Chao-Hung Lee, Sergio E. Rojter, Luis G. Podesta, Leonard Makowka, Stephen A. Geller, John M. Vierling
Journal: Hepatology (1995)

The role of hepatitis C virus (HCV) infection in fulminant hepatic failure is controversial. The frequency of serum HCV RNA positivity in previously reported patients with fulminant hepatic failure (FHF) of indeterminate cause ranged from 0 to 12% in the United States and Europe and from 43% to 59% in Asia. We assessed serum HCV RNA using polymerase chain reaction (PCR) and oligoprimers from the 5′UTR of the HCV genome in 26 consecutive patients with FHF. Another laboratory independently performed PCR on 21 of the serum samples using different oligoprimers from the 5′UTR and NS3 region of the HCV genome. Serum HCV RNA was detected in two of seven (28%) patients with hepatitis B, 9 of 15 (60%) with an indeterminate cause, and in none with hepatitis A (n = 2) or drug-induced hepatotoxicity (n = 2). HCV RNA PCR results were concordant between both laboratories in 17 of 21 (81%) of samples. In patients with an indeterminate cause, HCV RNA positivity was significantly associated with the transmission risk factor of low socioeconomic status and Hispanic ethnicity. Eighteen patients underwent liver transplantation (LT) and 15 (83%) survived. Among patients with FHF of indeterminate cause, recurrent or acquired HCV infection after transplantation occurred in three of five (60%) and one of four (25%) patients, respectively. Three of four (75%) patients with hepatitis C virus infection post-LT also developed histologic hepatitis. HCV appears to be the causative agent of a substantial number of cases of FHF classified as indeterminate in the Los Angeles area. Differences in patient populations or risk factors may explain the discordant incidences of HCV infection in FHF observed among different programs. (Hepatology 1995; 22:1379-1386).
Letter: The magic diploma.
Authors: W Stewart, Laura Fleming
Journal: BMJ (1973)

scdium as well as ultrafiltration-induced movements of sodium and of water across the dialyser.Conventional hyponatric dialysis is thus inherertly more difficult to control clinically, and would seem even more so when combined with individualized oral doses of Slow Sodium as advocated by Dr. Catto and his colleagues.-Weare, etc.,
Tricyclic Antidepressants-Reply
Authors: Neal Cutler
Journal: JAMA (1979)

<h3>In Reply.—</h3> Dr Coodley addresses several important issues, two of which we will address. Although we agree that there are subjective side effects at the 75-mg dose of imipramine, in studies of steady-state plasma levels of tricyclic antidepressants, loading doses of 100 mg of imipramine are routinely administered to naive subjects without side effects,<sup>1</sup>and elsewhere, no adverse reactions have been reported to initial 100-mg doses of other tricyclic antidepressants.<sup>2,3</sup>We believe that the urgency of attaining a steady-state plasma tricyclic level rapidly in a seriously depressed and potentially suicidal patient takes precedence over the risk of inducing possibly annoying side effects sufficient to encourage lack of adherence to therapeutic recommendations. Therefore, we believe that our recommendation of an initial 75-mg dose per day is safe, generally well tolerated, and a rational compromise between symptomatic irritation and therapeutic imperative. Regarding Dr Coodley's "central and crucial" point, we are
7. Diabetes Technology: <i>Standards of Medical Care in Diabetes—2020</i>
Journal: Diabetes Care (2019)

The American Diabetes Association (ADA) “Standards of Medical Care in Diabetes” includes the ADA’s current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, a multidisciplinary expert committee (https://doi.org/10.2337/dc20-SPPC), are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA’s clinical practice recommendations, please refer to the Standards of Care Introduction (https://doi.org/10.2337/dc20-SINT). Readers who wish to comment on the Standards of Care are invited to do so at professional.diabetes.org/SOC.
Contents
Authors: S Friedman, D Samuel, M Peck-Radosavljevic, M Charlton, T Dick, C Wegscheid, K Karimi, G Tiegs, P Fickert, A Andriulli, V Marco, M Margaglione, A Ippolito, G Fattovich, A Smedile, M Valvano, V Calvaruso, D Gioffreda, M Milella, F Morisco, M Felder, G Brancaccio, M Fasano, P Gatti, P Tundo, M Barone, R Cozzolongo, M Angelico, G Dõandrea, N Andriulli, M Abate, G Mazzella, G Gaeta, A Craxi, T Santantonio, K Nitschke, A Barriga, J Schmidt, J Timm, S Viazov, T Kuntzen, A Kim, G Lauer, T Allen, S Gaudieri, A Rauch, C Lange, C Sarrazin, T Eiermann, J Sidney, A Sette, R Thimme, D Lo ´pez, C Neumann-Haefelin, P Foka, E Karamichali, G Dalagiorgou, E Serti, P Doumba, G Pissas, A Kakkanas, D Kazazi, E Kochlios, M Gaitanou, J Koskinas, U Georgopoulou, P Mavromara, D Fransen Van De Putte, M Makris, K Fischer, T Yee, L Kirk, K Van Erpecum, D Patch, D Posthouwer, E Mauser-Bunschoten, M Carrieri, C Lions, P Sogni, M Winnock, P Roux, M Mora, P Bonnard, D Salmon, F Dabis, B Spire, A Tan, L Hoang, D Chin, E Rasmussen, U Lopatin, S Hart, H Bitter, T Chu, L Gruenbaum, P Ravindran, H Zhong, E Gane, S Lim, W Chow, P.-J Chen, R Petric, A Bertoletti, M Hibberd, G Papatheodoridis, J Goulis, S Manolakopoulos, A Margariti, X Exarchos, G Kokkonis, E Hadziyiannis, C Papaioannou, E Manesis, D Pectasides, E Akriviadis, A Coilly, B Roche, J Dumortier, V Leroy, D Botta-Fridlund, S Radenne, G.-P Pageaux, S.-N Si-Ahmed, O Guillaud, T Antonini, S Haı ¨m-Boukobza, A.-M Roque-Afonso, J.-C Duclos-Valle ´e, M Elias-Miro, M Mendes-Braz, R Cereijo, F Villarroya, M Jime ´nez-Castro, S Guixe ´-Muntet, M Massip-Salcedo, J Domingo, R Bermudo, J Rode, C Peralta, O Robinson, E Want, M Coen, R Kennedy, C Van Den Bosch, Y Gebrehawaria, H Kudo, F Sadiq, R Goldin, M Hauser, A Fenwick, M Toledano, M Thursz, C.-C Ling, K Ng, Y Shao, W Geng, J.-W Xiao, H Liu, C.-X Li, X.-B Liu, Y.-Y Ma, W.-H Yeung, X Qi, J Yu, N Wong, Y Zhai, S.-C Chan, R Poon, C.-M Lo, K Man, J Dyson, B Jaques, D Chattopadyhay, R Lochan, J Graham, D Das, T Aslam, I Patanwala, S Gaggar, M Cole, K Sumpter, S Stewart, J Rose, M Hudson, D Manas, H Reeves, F Hucke, W Sieghart, M Pinter, I Graziadei, W Vogel, C Mu, H Heinzl, F Waneck, M Trauner, S Zeng, T Yamashita, M Kondo, K Nio, T Hayashi, Y Hara, Y Nomura, M Yoshida, N Oishi, H Ikeda, M Honda, S Kaneko, A Kelly, R Fahey, J Fletcher, C Keogh, A Carroll, R Siddachari, J Geoghegan, J Hegarty, E Ryan, C Oõfarrelly
Journal: Journal of Hepatology (2013)
Progress Toward Achieving the National 1990 Objectives for Injury Prevention and Control
Journal: JAMA (1988)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
GIOVANNI BORELLI (1608-1679)— IATROMECHANICAL PHYSIOLOGIST
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Approaches for Assessing Health Risks from Complex Mixtures in Indoor Air: A Panel Overview
Authors: Carol J. Henry, Lawrence Fishbein, William J. Meggs, Nicholas A. Ashford, Paul A. Schulte, Henry Anderson, J. Scott Osborne, Daniel W. Sepkovic
Journal: Environmental Health Perspectives (1991)

Critical to a more definitive human health assessment of the potential health risks from exposure to complex mixtures in indoor air is the need for a more definitive clinical measure and etiology of the health effects of complex mixtures. This panel overview highlights six of the eight presentations of the conference panel discussion and features a number of the major topical areas of indoor air concern. W. G. Meggs assessed clinical research priorities with primary focus on the role of volatile organic chemicals in human health, recognizing the areas where definitive data are lacking. By recognizing many types of chemical sensitivity, it may be possible to design studies that can illuminate the mechanisms by which chemical exposure may cause disease. The critically important topic of multiple chemical sensitivity was discussed by N. A. Ashford, who identified four high risk groups and defined the demographics of these groups. P. A. Schulte addressed the issue of biological markers of susceptibility with specific considerations of both methodological and societal aspects that may be operative in the ability to detect innate or inborne differences between individuals and populations. Three case studies were reviewed. H. Anderson discussed the past and present priorities from a public health perspective, focusing on those issues dealing with exposures to environmental tobacco smoke and formaldehyde off-gassing from materials used in mobile home construction. J. J. Osborne described several case studies involving wood smoke exposure to children, with emphasis on the significantly greater occurrence of chronic respiratory symptoms and acute chest illness for children from homes heated with woodburning stoves.(ABSTRACT TRUNCATED AT 250 WORDS)
The patient with syncope
Authors: R. J. Noble
Journal: JAMA (1977)

SYNCOPE, which is a sudden transient loss of consciousness, results from an impairment in cerebral metabolism, which is the consequence of a brief deprivation in essential energy substrates, specifically oxygen and glucose. This deprivation in energy substrates may originate from one of only four levels (Fig 1): (1) from decrease or loss of intrinsic cerebral circulation, (2) from the heart, as a result of a transient decrease in cardiac output, (3) from a decrease in systemic arterial pressure to values inadequate to perfuse the brain, or (4) from insufficient energy substrates contained in the blood delivered to the brain. After reviewing the physiological mechanisms of syncope involved at each of these levels of potential abnormality, this article will attempt to simplify and organize the diagnostic approach to syncope into a conveniently manageable scheme. <h3>PHYSIOLOGICAL MECHANISM Obstruction to Cerebral Blood Flow</h3> At this level, the mechanism of the reduction in cerebral
Drug use data: a different perspective
Authors: A. M. Lee
Journal: JAMA (1975)

IT IS AN occupational hazard of advocates to overstate the size of the problems their innovations might correct and the benefits of their proposed solutions. The average physician makes due allowance for such possible bias when listening to a pharmaceutical company's sales representative. However, he may not be equally aware of the same potential for bias when listening to the advocate of some new proposal for "upgrading" the quality and rationality of health care. One such advocate is T. Donald Rucker, PhD. In an article<sup>1</sup>inThe Journal, Dr. Rucker proposed a computerized drug information system that would provide, among other benefits, a means for ongoing peer review of medications prescribed. To oppose utilization review in any form is equivalent to attacking motherhood. It is an idea that has been widely accepted in principle and applied in practice for many years, as any member of a hospital tissue committee
Herbal Medicine
Authors: Horst H. Bielefeld
Journal: JAMA (1975)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Bilopaque: A New Cholecystographic Medium
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Long-term end results of treatment of cancer
Authors: S. J. Cutler
Journal: JAMA (1971)

The 20-year survival rate, adjusted for normal mortality expectation, is a meaningful measure of the proportion of successfully treated patients. Twenty-year rates for patients treated recently can be projected by comparing survival curves for successive calendar periods. Available data permit projections for patients with cancers of the colon, rectum, bladder, and female reproductive system. The estimated proportion of successfully treated patients is encouragingly high for those with resectable tumors and no evidence of spread beyond the site of origin: 85% for uterus, 75% for ovary, and 60% for colon, rectum, breast, and bladder.
1941 Letter
Authors: Meyer Bloom
Journal: JAMA (1983)

<h3>To the Editor.—</h3> An idea has been plaguing me recently, and it is to determine the reaction of the medical profession toward this thought that I write this message. Many of our colleagues have willingly answered the call of their country to join the armed forces. Many of them have been asked to give up lucrative practices and administer medical service to our soldiers, sailors, and marines. Many of them have left wives and families behind to continue living as before. At the same time, we have remained behind, still practicing our art. It is true that some of us contribute in other ways, such as by giving to the USO or examining selectees without pay. But we are still with our families and still earning more substantially than those who have gone forward to help rid the world of this demon and his cohort. Now, my appeal is not
Adding amynoglycoside to βlactam does not improve results
Journal: BMJ (2004)

sweating.His wife brought him to the emergency department on three occasions-16, 19, and 23 days after starting diclofenac-and he was noted to be hypoglycaemic with blood glucose concentrations of 1.2-2.5 mmol/l.At each visit his symptoms responded to intravenous glucose and feeding.No investigations were done at his first two visits to the emergency department.At his third visit, his blood glucose concentration was 1.2 mmol/l.A history taken at this visit after correction of hypoglycaemia was unremarkable.The patient reported no decrease in his appetite or increase in physical activity in the past month and no decrease in urine output.Physical examination was unremarkable, with a blood pressure of 150/90 mm Hg.There was no peripheral oedema.Investigations showed a raised serum creatinine concentration of 440 mol/l and a raised serum urea concentration of 14.6 mmol/l (1.7-8.3 mmol/l); serum potassium concentration was 4.8 mmol/l (3.5-5.0 mmol/l).Since starting to take the non-steroidal antiinflammatory drug diclofenac, the patient had developed a decline in renal function with a fourfold increase in serum creatinine.Diclofenac was immediately stopped and his insulin dosage was decreased.Two weeks later, his serum creatinine concentration returned to baseline and he resumed his usual insulin dosage, with no further episodes of hypoglycaemia and with reasonable glucose control. DiscussionNon-steroidal anti-inflammatory drugs (NSAIDs) are commonly used for managing pain.They can cause acute renal failure in susceptible individuals by inhibiting the synthesis of renal vasodilatory prostaglandins. 6 In the general population, the frequency of acute renal failure from NSAIDs is not known but is probably less than 1% a year. 7A French review of 2000 patients with acute renal failure, however, found that 6.8% of the cases were associated with NSAIDs. 8 In chronic, progressive renal failure the physician is aware of the risk associated with NSAIDs and adjusts the dose of insulin or hypoglycaemic agents accordingly.However, when renal dysfunction is unexpected, a patient with poorly controlled glucose concentrations may notice improvement in glycaemic control or hypoglycaemia because of the decreased requirement for insulin or hypoglycaemic agents, and both the physician and the patient may be pleased with this desired but passive improvement in glycaemic control.In such patients, it is important to check that there has been no recent decline in their renal function.
Trends in quality of screening colonoscopy in Austria
Authors: Elisabeth Waldmann, Irina Gessl, Daniela Sallinger, Philip Jeschek, Martha Britto-Arias, Georg Heinze, Elisabeth Fasching, Werner Weiss, Michael Gschwantler, Michael Trauner, Monika Ferlitsch
Journal: Endoscopy (2016)

Correction to: Trends in quality of screening colonoscopy in AustriaEndoscopy 2016; 48(12): 1102-1109DOI: 10.1055/s-0042-113185
BRAZIL
Journal: JAMA (1953)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
La pratique des deviations vertébrales: (scoliose—cyphose— lordose).
Journal: JAMA (1926)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal