XANTHOMA DIABETICORUM
Authors: E G MARGOLIN
Journal: Annals of Internal Medicine (1953)

Case Reports1 September 1953XANTHOMA DIABETICORUMESAR GORDON MARGOLINESAR GORDON MARGOLINSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-39-3-629 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn recent years cholesterol and its esters have been singled out of the lipid constituents of the body for special consideration, largely because of their relationship to atheromatous changes and partly because of their chemical similarities to adrenal and sexual hormones. Clinicians have been impressed with the importance of the cholesterol levels in certain disease states, and the measurement of cholesterol is now a standard test in most clinical laboratories. A recent case of xanthoma diabeticorum, manifesting striking alterations in cholesterol metabolism occurring in the course of uncontrolled diabetes mellitus, is presented.CASE REPORTPresent Illness:A 21 year old...Bibliography1. AddisonGull TW: On a certain affection of the skin, vitiligoidea—(a) plana; (b) tuberosa, with remarks, Guy's Hosp. Rep. 7: 265, 1851. Cited by Thannhauser.8 Google Scholar2. McGavackShepardson THHC, cited by Buchanan, J. A., and Indelicato, J. C.: A case of xanthoma diabeticorum associated with diabetes mellitus and acromegaly, Am. J. M. Sc. 195: 50-53, 1938. CrossrefGoogle Scholar3. JoslinRootWhiteMarbleBailey EPHFPACC: The treatment of diabetes mellitus, 1946, Lea and Febiger, Philadelphia, pp. 593-595. Google Scholar4. Diamond , cited by Joslin.3 Google Scholar5. Major , cited by Sutton and Sutton.7 Google Scholar6. Beerman H: Lipid diseases as manifested in the skin, M. Clin. North America 35: 433-456, 1951. CrossrefMedlineGoogle Scholar7. SuttonSutton RLRL: Diseases of the skin, 1939, The C. V. Mosby Co., St. Louis, pp. 391-393, 866-871. Google Scholar8. Thannhauser SJ: Lipidoses, diseases of the cellular lipid metabolism, 1950, Oxford University Press, New York. Google Scholar9. CarfagnoSteiger SCWA: The serum lipids in lipemia retinalis, Am. J. M. Sc. 221: 379-383, 1951. CrossrefMedlineGoogle Scholar10. NadbathFauteux RPLZ: Diabetic lipemia retinalis, U. S. Armed Forces M. J. 3: 319-322, 1952. MedlineGoogle Scholar11. CurtisSheldonEckstein ACJMHC: Experimental reproduction of lipemia, Am. J. M. Sc. 186: 548-556, 1933. CrossrefGoogle Scholar12. ParkerCuller WRAM, cited by Curtis and Sheldon.11 Google Scholar13. Allen FM, cited by Curtis and Sheldon.11 Google Scholar14. Garb J: Lipid metabolism in relation to xanthoma diabeticorum with a recommendation for a new nomenclature, Ann. Int. Med. 19: 241-252, 1943. LinkGoogle Scholar15. Duncan GG: Diseases of metabolism, 1947, W. B. Saunders Co., Philadelphia. Google Scholar16. Spencer MC: Xanthoma diabeticorum, Arch. Dermat. and Syph. 64: 92-93, 1951. Google Scholar17. FrankLevitt LLM: Idiopathic hyperlipemia with secondary xanthomatosis, Arch. Dermat. and Syph. 64: 434-436, 1951. CrossrefGoogle Scholar18. DelevettBruger AFM: Plasma lipids in primary (xanthomatosis) and secondary hypercholesterolemia, Arch. Int. Med. 81: 859-867, 1948. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: MC Omaha, Nebraska*Received for publication March 18, 1953.From the Medical Service, 382d General Hospital, APO 54, c/o PM, San Francisco.Present address: 116 So. 50 St., Omaha. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDiabetes and Diseases of the SkinThe diet and the development of coronary heart disease 1 September 1953Volume 39, Issue 3Page: 629-635KeywordsApolipoproteinsCholesterolClinical laboratoriesDiabetes mellitusHormonesLipidsMedical services ePublished: 1 December 2008 Issue Published: 1 September 1953 PDF downloadLoading ...