Concerns About Meta-analysis of Glucose Control and Cardiovascular Disease in Type 2 Diabetes
Authors: Tanika N. Kelly
Journal: Annals of Internal Medicine (2010)

Letters5 January 2010Concerns About Meta-analysis of Glucose Control and Cardiovascular Disease in Type 2 DiabetesTanika N. Kelly, PhD, MPH and Jiang He, MD, PhDTanika N. Kelly, PhD, MPHFrom Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112. and Jiang He, MD, PhDFrom Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-152-1-201001050-00018 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:We thank Drs. Yudkin and Richter for their interest in our meta-analysis. The decision to analyze the subgroups of early and more recent trials was an a priori determination based on important differences in patient populations, targeted hemoglobin A1c levels, and treatment regimens. Specifically, the early UKPDS trials included only patients with newly diagnosed diabetes, whereas the more recent ACCORD (Action to Control Cardiovascular Risk in Diabetes), ADVANCE (Action in Diabetes and Vascular Disease), and VADT (Veterans Affairs Diabetes Trial) studies included patients with prevalent diabetes. The intensive glucose control target in the UKPDS was similar to the ...References1. UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet. 1998;352:837-53. [PMID: 9742976] CrossrefMedlineGoogle Scholar2. Glesser LJ, Olkin I. Stochastically dependent effect sizes.. In: Cooper H, Hedges LV, eds. The Handbook of Research Synthesis. New York: Sage; 1994:339-56. Google Scholar3. Sutton AJ, Abrams KR, Jones DR, Sheldon TA, Song F, eds. Generalized synthesis of evidence—combining different sources of evidence.. In: Sutton AJ, Abrams KR, Jones DR, Sheldon TA, Song F, eds. Methods for Meta-analysis in Medical Research. New York: J Wiley; 2000:259-76. Google Scholar Author, Article, and Disclosure InformationAffiliations: From Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112.Disclosures: None disclosed. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoSystematic Review: Glucose Control and Cardiovascular Disease in Type 2 Diabetes Tanika N. Kelly , Lydia A. Bazzano , Vivian A. Fonseca , Tina K. Thethi , Kristi Reynolds , and Jiang He Concerns About Meta-analysis of Glucose Control and Cardiovascular Disease in Type 2 Diabetes John S. Yudkin and Bernd Richter Metrics Cited byEvaluation of glycemic control status and its associated factors among diabetes patients on follow-up at referral hospitals of Northwest Ethiopia: A cross-sectional study, 2020Determinants of poor glycemic control among adult patients with type 2 diabetes mellitus in Jimma University Medical Center, Jimma zone, south west Ethiopia: a case control study 5 January 2010Volume 152, Issue 1Page: 63-64KeywordsCardiovascular diseasesClinical trialsGlucoseHemoglobinHypoglycemicsInsulinPopulation statisticsType 2 diabetesVascular diseases ePublished: 5 January 2010 Issue Published: 5 January 2010 Copyright & PermissionsCopyright © 2010 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...