tbuckley/cabot-search huggingface dataset:
Controlling the Tuberculosis Epidemic: The Analogy With Mental Illness
Authors: Joseph R. Cowen
Journal: JAMA (1993)

<h3>To the Editor.</h3> —Mr Gostin<sup>1</sup>proposes that "Constitutional adjudication in the field of civil commitment of persons with mental illness provides an apt model for tuberculosis [TB] [control] statutes." In failing to recognize the differences, as well as the similarities between TB and mental illness, he risks making the same errors that have resulted in civil procedures that now plague care of mental illness. The issue of "imminent danger" to self and others, in mental illness, has poor definition and unreliable predictability. In TB, "imminent danger" is definable and reliably predictable. The similarity is that ill persons may not know that they are ill. This ignorance poses danger to self for both TB and mental illness sufferers, although not with the same degree of certainty for morbidity and mortality. They differ in that TB can be casually transmitted to others by ordinary behavior (cough). Mental illness poses a danger
THE POSSIBILITIES FROM FELLOWSHIP IN THE COUNTY SOCIETY.
Journal: JAMA (1905)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
<i>Erratum:</i> Vol. 66, No. 34
Journal: MMWR Morbidity and Mortality Weekly Report (2017)

the caption should have read as follows:"In 2016, 38.1% of adults aged ≥18 years never had pain, 42.6% had pain on some days, and 19.4% had pain most days or every day in the past 6 months.A higher percentage of adults who were previously employed (29.8%) had pain most days or every day compared with never employed adults (18.6%) and currently employed adults (15.1%).Never employed adults (41.9%) and currently employed adults (40.4%) were more likely to report never having had pain than previously employed adults (31.2%)."
Metronidazole and hepatic abscess. A false-positive response
Authors: J. G. Kane
Journal: JAMA (1976)

METRONIDAZOLE is a nitroheterocyclic compound with established efficacy in the treatment of trichomaniasis since 1959. Evaluation of metronidazole for use in the treatment of intestinal amebiasis followed its discovery, and the first successful trials were reported in 1966. Since then it has been shown to be effective in the treatment of all forms of amebiasis. Recently, its efficacy and low incidence of side effects compared to alternate drugs has led to its designation as the drug of choice for moderate to severe intestinal amebic disease and amebic hepatic abscess. In fact, recent literature has stressed the usefulness of a therapeutic trial of metronidazole in distinguishing between pyogenic and amebic liver abscess. We wish to report a falsepositive response as a caveat to its use in this regard. <h3>Report of a Case</h3> A 46-year-old butcher was admitted to the Veterans Administration Hospital forexamination. He had fever, chills, weight loss, diarrhea, and
Rabid Ferret-Badgers in Taiwan
Journal: JAMA (2014)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Ampicillin for Typhoid Carriers
Authors: K. F. Anderson
Journal: BMJ (1964)

BJORNAL 1593 only one survivor has been reported from haemorrhage into the peritoneal cavity.Several surgical operations have been tried for this condition,3 such as excision of the aneurysm followed either by end-to-end suture of the hepatic artery or by anastomosis of the proximal end of the splenic artery (after splenectomy) with the distal end of the hepatic artery.We are grateful to Mr. J.
Phase II study of panitumumab, nab-paclitaxel, and carboplatin followed by FEC neoadjuvant chemotherapy for patients with primary HER-2 negative inflammatory breast cancer.
Authors: Naoko Matsuda, Ricardo H. Alvarez, Savitri Krishnamurthy, Jie S. Willey, Xiaoping Wang, Bora Lim, Charla A. Parker, Angela Marx, Gildy Babiera, Daniel J. Booser, James L. Murray, Banu Arun, Abenaa M. Brewster, James M. Reuben, Wendy A. Woodward, Anthony Lucci, Sarah Marie Gainer, Debu Tripathy, Vicente Valero, Naoto T. Ueno
Journal: Journal of Clinical Oncology (2015)

1065 Background: EGFR overexpression is an independent poor prognostic factor in patients with inflammatory breast cancer (IBC). Our IBC animal model indicates that EGFR targeted therapy inhibited IBC tumor growth. It will reverse epithelial mesenchymal transition. Historically, the pathological complete response (pCR) rate in IBC has been 15%. We determined the effect of an anti-EGFR monoclonal antibody (panitumumab) of neoadjuvant chemotherapy by determining the pCR rate. Methods: In this single-arm, phase II prospective study, the patients received 4 cycles of combination panitumumab (2.5 mg/kg), nab-paclitaxel (100 mg/m2), and carboplatin (AUC 2) on a weekly schedule (PNC). After the PNC regimen was completed, 4 cycles of FEC (5-fluorouracil, 500 mg/m2; epirubicin, 100 mg/m2; cyclophosphamide, 500 mg/m2) was administered followed by surgical resection, radiation and hormonal therapy (ER+). The primary end point was the pCR rate. The secondary objectives were disease-free survival, safety and to identification of biomarkers. Results: We analyzed 25 IBC patients. Median age was 57 years (range 23-68 years). 15 were HR+/HER2- and 10 were HR-/HER2- (TNBC). The median follow-up time was 11.7 months (range, 8.7-33.9 months). The pCR rate was 36% (95% CI: 0.18-0.58). Six (60%) TNBC patients and 3 (20%) HR+/HER2- patients achieved pCR. Five patients experienced disease recurrence, and 4 died. The frequency of grade 3 or 4 hematological events was 18 (72%), grade 3 nonhematological adverse events were seen in 9 (36%) patients, (rash, n = 5; fatigue, n = 2; infection, n = 1; anorexia, n = 1; stomatitis, n = 1; pleuritic pain, n = 1) and grade 4 was 0 during the PNC regimen.The association between pCR and subtype has trending for significance (p = 0.087). There was no correlation between pCR and biomarker expression (EGFR, COX2, Nodal, E-Cadherin, Vimentin, ALDH1 expression) in 14 samples. Conclusions: Our data show that this novel treatment, based on the biological characteristics of IBC, produced unprecedentedly high pCR rates in TNBC. We plan to conduct a randomized study to determine the role of this regimen compared with standard regimens. Clinical trial information: NCT01036087.
THE USE OF BULK ETHER IN ANESTHESIA
Journal: JAMA (1942)

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Pediatrics
Authors: Christina Robohm, Nancy Cole, Gerald B. Merenstein
Journal: JAMA (2004)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Quantitative Criteria for the Neurosurgery of Parkinsonism
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Prognostic and predictive factors from the phase III CELESTIAL trial of cabozantinib (C) versus placebo (P) in previously treated advanced hepatocellular carcinoma (aHCC)
Authors: T. Yau, T. Meyer, R.K. Kelley, M. Mangeshkar, A.-L. Cheng, A.B. El-Khoueiry, G.K. Abou-Alfa
Journal: Annals of Oncology (2019)
Tetracycline resistance in pneumococci and group A streptococci. Report of an ad-hoc study group on antibiotic resistance.
Authors: I Porter, J Emslie, R Fallon, J Gould, J Selkon, R Peel, A Percival, P Cavanagh, R Wise, M Lewis, T Brogan, M Robertson, D Leigh, I Phillips, N Simmons, J Williams, E Stokes, D Reeves, G Churcher, J Kensit, ; Farrell, S Evans
Journal: BMJ (1977)

In a nationwide survey in the spring of 1975 into the prevalence of tetracycline resistance among pneumoccoci and group A streptococci isolates, 21 laboratories reported the sensitivity of isolates and details of the patients. Altogether 13% of the 1528 pneumococci isolated were resistant to tetracycline, but there were wide geographical variations. Thirty-six per cent of the 1515 streptococci isolated were resistant, and again there was considerable geographical variation. A high level of resistance in one organism did not correlate with a high level in the other. For both organisms resistance was commoner among inpatients and those aged 50 or over. Tetracycline should probably not be the drug of choice in penicillin-sensitive patients with group A streptococcal infections, but geographical variations were so wide that decisions on treatment are best made on the basis of local survey data.
Tuberculosis and Acute General Miliary Tuberculosis. By Dr. G. Cornet of Berlin.
Journal: JAMA (1904)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Airwaves
Authors: W. Wedzicha
Journal: Thorax (2005)

<h3>SUMMARY</h3> The competence pili of transformable Gram-positive species form a subset of the diverse and widespread class of extracellular filamentous organelles known as type IV pili (T4P). In Gram-negative bacteria, T4P act through dynamic cycles of extension and retraction to carry out diverse activities including attachment, motility, protein secretion, and DNA uptake. It remains unclear whether T4P in Gram-positive species exhibit this same dynamic activity, and their mechanism of action for DNA uptake remains unclear. They are hypothesized to either (1) passively form transient cavities in the cell wall to facilitate DNA passage, (2) act as static adhesins to enrich DNA near the cell surface for subsequent uptake by membrane-embedded transporters, or (3) play an active role in translocating bound DNA via their dynamic activity. Here, using a recently described pilus labeling approach, we demonstrate that pneumococcal competence pili are highly dynamic structures that rapidly extend and retract from the cell surface. By labeling ComGC with bulky adducts, we further demonstrate that pilus retraction is essential for natural transformation. Together, our results indicate that Gram-positive type IV competence pili are dynamic and retractile structures that play an active role in DNA uptake. <h3>Short summary</h3> Competent pneumococci kill non-competent cells on contact. Retractable DNA-binding fibers in the class of type IV pili may provide a key tool for retrieving DNA segments from cell wreckage for internalization and recombination.
Establishment of a National Surveillance Program for Antimicrobial Resistance in Salmonella
Journal: JAMA (1996)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Sexual differences in cancer survival: hormones or stage at diagnosis?
Authors: Julianne Byrne, Thomas R. Fears, H. Stacy Nicholson
Journal: JAMA (1990)

<h3>To the Editor.—</h3> We attempted to confirm the finding of Adami et al<sup>1</sup>in our cohort of long-term survivors of childhood and adolescent cancer, described more fully elsewhere.<sup>2</sup>Between 1980 and 1983 we interviewed 2300 long-term (&gt;5 years after diagnosis and ≥21 years of age) survivors of cancer diagnosed before the age of 20 years or their proxies. The survivors were 32 years old on average at the time of follow-up and had been diagnosed at an average age of 14.5 years. In this cohort analysis we evaluated mortality in survivors starting from the time when they became eligible for the cohort as defined above. Hazard rates within categories were calculated as the number of events divided by the estimated person-years of follow-up, and significance tests assumed that rates were constant across 5-year periods. We found, as did Adami et al, that compared with males, female survivors were
A Clinical Guide to Bedside Examination.
Journal: JAMA (1923)

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Grief Therapy More Effective for Bereaved Adults Than Psychotherapy
Journal: JAMA (2014)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal