tbuckley/cabot-search huggingface dataset:
Biochimica et Biophysica Acta, Amsterdam
Journal: JAMA (1967)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Multiple Metal Contamination from House Paints: Consequences of Power Sanding and Paint Scraping in New Orleans
Authors: Howard W. Mielke, Eric T. Powell, Aila Shah, Christopher R. Gonzales, Paul W. Mielke
Journal: Environmental Health Perspectives (2001)

Power sanding exterior paint is a common practice during repainting of old houses in New Orleans, Louisiana, that triggers lead poisoning and releases more than Pb. In this study we quantified the Pb, zinc, cadmium, manganese, nickel, copper, cobalt, chromium, and vanadium in exterior paint samples collected from New Orleans homes (n = 31). We used interior dust wipes to compare two exterior house-painting projects. House 1 was measured in response to the plight of a family after a paint contractor power sanded all exterior paint from the weatherboards. The Pb content (approximately 130,000 microg Pb/g) was first realized when the family pet died; the children were hospitalized, the family was displaced, and cleanup costs were high. To determine the quantity of dust generated by power sanding and the benefits of reducing Pb-contaminated dust, we tested a case study house (house 2) for Pb (approximately 90,000 microg/g) before the project was started; the house was then dry scraped and the paint chips were collected. Although the hazards of Pb-based paints are well known, there are other problems as well, because other toxic metals exist in old paints. If house 2 had been power sanded to bare wood like house 1, the repainting project would have released as dust about 7.4 kg Pb, 3.5 kg Zn, 9.7 g Cd, 14.8 g Cu, 8.8 g Mn, 1.5 g Ni, 5.4 g Co, 2.4 g Cr, and 0.3 g V. The total tolerable daily intake (TTDI) for a child under 6 years of age is 6 microg Pb from all sources. Converting 7.4 kg Pb to this scale is vexing--more than 1 billion (10(9)) times the TTDI. Also for perspective, the one-time release of 7.4 x 10(9) microg of Pb dust from sanding compares to 50 x 10(9) microg of Pb dust emitted annually per 0.1 mile (0.16 km) from street traffic during the peak use of leaded gasoline. In this paper, we broaden the discussion to include an array of metals in paint and underscore the need and possibilities for curtailing the release of metal dust.
Questions and Answers
Journal: JAMA (1988)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
STANDARDIZED DRUGS.
Authors: HENRY B. GILPIN
Journal: JAMA (1896)

It is interesting to study, in the evolution of the methods of drug administration, the various forms that have obtained. Beginning with the crude drug, the first step apparently was the recognition of the fact that, as a rule, the soluble principles of a drug of vegetable origin, were its therapeutically active ones. Hence it was but natural that solutions—made with hot or cold water—in the form of infusions, decoctions, etc., should have resulted. It was found, however, that the proneness of these to decomposition, and the relatively large doses necessary to secure therapeutic effects, made them objectionable. The next step was the making of tinctures, fluid extracts and similar products. The final advance has been the assaying or standardizing of the more prominent drugs and galenical preparations, such as those of cinchona, opium and nux vomica, as directed by our Pharmacopeia, and a score and more of other alkaloid-containing
Roger Freeman
Authors: Everard Forde, Wend De, Jeannette Cayley
Journal: BMJ (2004)

Forde Cayley went from medical school straight into service in wartime France and then to Singapore.Captured by the Japanese, he was taken to the infamous River Kwai.The horrors he had witnessed never left him, but he believed in reconciliation, not hatred.As a postwar pioneer of drug treatment for tuberculosis, he took up the respiratory medicine post that he held until retirement.His spare time was divided between BMA activities, his work as a lay reader, and in his prolific vegetable plot.Predeceased by his wife, Eileen, he leaves two sons and three grandsons.
Consultants' Superannuation
Authors: R. D. Rowlands
Journal: BMJ (1973)

vaccination had readily paid £150 for a holiday for two, £10 for his Dassport, and £7 to park his car at the airport.If doctors are unble or unwilling to alter their open-ended contract with the Government, at least let there -be proper professional respect in the private sector.-I am, etc.,
Manuscripts Approved for JNCI During September–October, 1975
Journal: JNCI Journal of the National Cancer Institute (1975)

Manuscripts Approved for JNCI During September–October, 1975 Get access JNCI: Journal of the National Cancer Institute, Volume 55, Issue 5, November 1975, Pages 1259–1261, https://doi.org/10.1093/jnci/55.5.1259-e Published: 01 November 1975
Toxicology and Applied Pharmacology, New York
Journal: JAMA (1966)

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Massachusetts Medical Society
Authors: John Figgis Jewett
Journal: New England Journal of Medicine (1958)

COMMITTEE ON MATERNAL WELFAREDefect of Interventricular Septum, with Cardiac Failure and Pulmonary AtherosclerosisAn eighteen-year-old primigravida had had pulmonary hypertension and hypertrophy of the right ventricle substantiated at the age of eleven by x-ray study, electrocardiography and cardiac catheterization. The diagnosis was defect of the interventricular septum. She failed to return for further studies, but remained on somewhat limited exercise, tiring easily and susceptible to frequent respiratory infections. She did not gain weight normally as she matured but led a fairly normal life without serious cardiac embarrassment. She had been slightly cyanotic for two years and was slightly more . . .
Brit J Pharmacol, London
Journal: JAMA (1970)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Third national conference on American Indian health
Authors: A. Fahy
Journal: JAMA (1965)

Mental health and trachoma are emerging as major health problems among American Indians, as intensive prevention and treatment programs are improving the outlook for the conquest of such systemic infectious diseases as tuberculosis. To focus attention on the increase in mental disorders and the recurrence of trachoma, once almost completely controlled on the reservations, and to consider approaches of their solution, the National Committee on Indian Health of the Association on American Indian Affairs, last fall, called its third conference on Indian health. The first conference had been held in 1953 to consider whether to recommend the transfer of Indian health services from the Bureau of Indian Affairs, Department of the Interior, to the Public Health Service, a transfer which was subsequently effected. The second conference, in 1955, was concerned with questions related to the administrative change. The third conference was held in New York on Nov 19, 1964. There
Robust benefit of platelet GP IIb-IIIa inhibition with eftifibatide in patients undergoing stent PCI with hot or cold presentation Bleakley Chandler, John Conor O'Shea, Sally Greenberg, James Slater, James M. Kirshenbaum, Joseph B. Muhlestein, Cindy M. Pacchiana, Todd J. Lorenz, Kristin Raffetto, Michael M. Kitt, James E. Tcheng. University Hospital, Augusta, GA, Duke Clinical Research Institute, Durham, NC
Journal: Journal of the American College of Cardiology (2001)
The Croonian Lectures on the Influence of the Circulation upon the Nervous System
Authors: W. Moxon
Journal: BMJ (1881)

Injection sclerotherapy is now the accepted first line treatment for bleeding oesophageal varices, although it is associated with an impressive list of rare complications. The main problem concerns the strategy for uncontrollable or recurrent bleeding. Patients with uncontrolled bleeding may be referred for surgery after considerable blood loss and are then extremely difficult to assess. The effects of blood loss on liver function can lead to an unduly pessimistic assessment of liver status. An effective choice of emergency surgical procedure may require considerable surgical expertise. Oesophageal transection and devascularisation are satisfactory for many patients with oesophageal varices secondary to cirrhosis and should nearly always control bleeding. Difficulties arise in patients who are grossly obese and in those who have undergone extensive surgery in the upper abdomen. Problems may also be encountered in those treated by repeated sclerotherapy, which may have caused severe inflammatory change and thickening around the lower oesophagus and upper stomach. We believe that an emergency mesocaval shunt using either a vein graft or a synthetic material such as polytetrafluoroethylene is the procedure of choice for this difficult group of very sick patients. The surgical exposure is satisfactory and not unduly prolonged in even the largest patients and the technique does not interfere with any subsequent transplant operation. There is a greater choice in the management of the patient with less urgent bleeding from recurrent varices after sclerotherapy. Repeat sclerotherapy may be effective for small oesophageal varices while liver transplantation may be indicated in the patient with deteriorating liver function. A selective distal splenorenal shunt should be considered for patients with intact splenic and left renal veins and a mesocaval vein graft for the remainder. We would therefore suggest that surgery should still be considered for the management of portal hypertension, particularly in the following circumstances: (1) Uncontrollable bleeding during the initial course of sclerotherapy; (2) Life threatening haemorrhage from recurrent varices; (3) Bleeding from ectopic varices not accessible to sclerotherapy; (4) Uncontrollable bleeding from oesophageal ulceration secondary to injection sclerotherapy; (5) Severe, symptomatic hypersplenism; (6) For patients who live in communities remote from blood transfusion facilities and adequate medical care. The management of the complications of portal hypertension continues to pose problems. We believe that the best results should come from a combined management approach using injection sclerotherapy as primary treatment and surgery for complications and for haemorrhage from unusual anatomical sites.
In vivo response-adapted dose-dense (dd) doxorubicin and cyclophosphamide (AC) -&gt; weekly carboplatin and albumin- bound paclitaxel (nab-TC) plus trastuzumab (H) or bevacizumab (B) in patients with large and inflammatory breast cancer (BC): A phase II study
Authors: R. S. Mehta
Journal: Journal of Clinical Oncology (2008)

11569 Background: In prior studies (ASCO 2005–07) at our institution, a 72% (21/29, 10/15 [67%] AC-resistant subset) pathologic complete response (pCR) with dd AC ->weekly (wkly) cemophor (c)-TCH in HER2+BC in contrast to 27% (9/35) pCR with dd AC->c-TC in HER2-BC was achieved. We substituted nab-T for c-T in all and added B in HER2-BC to exploit the preclinical synergy between nab-T and B in the current study (prelim. ASCO 2007). Methods: Patients (pts) with stage II-IV BC were enrolled with median age of 51 (range 28–76). Pts received in vivo response-adjusted AC (8 completed 4 and 35 ≤ 2 cycles) ->wkly 9–12 nab-T at 100 mg/m2 and C (AUC of 2), both 3 wks on, 1 wk off. HER2+ pts received concurrent 16 wkly H (4mg/kg induction, 2mg/kg maintenance) and HER2- pts received 6–8 bi-wkly B (10 mg/kg). Results: Adverse event with dd AC included neutropenic fever in 3 pts (2 on pegfilgrastin, 1 on GM-CSF). One (with CVD) of 15 pts treated with nab-TCH had asymptomatic grade III decline in ejection fraction. Median EF on baseline was 66% (59–78%), post 2 AC 68% (56–84%) and post nab-TCH 63% (47–68%). pCR was documented in 5/15 (33%) AC-resistant HER2+, 7 of 28 (25%) HER2-, 0/9 lobular/mixed ductal&lobular, 5/11(45%) HR-, 7/29 (24%) HR+, and 0/3 metaplastic BC. Ten additional tumors were reduced to ≤ 5 mm. Progression-free survival at a median follow-up of 18 months (range 10–27 months) is 81%, and 97% after excluding stage IV progressors (7 of 10 stage IV pts progressed). Only one pt with stage IIIB metaplastic BC has died. Conclusions: The lower pCR rate in the current study compared to the prior study in HER2+BC may be due to higher percentage of HR+ and lobular BC, and requirement of AC-sensitivity documentation by all modalities as compared to documentation by one modality in prior study. This limited AC administration to 2 cycles in all HER2+ pts. However, the lower rate of pCR in AC-resistant HER2+BC is still higher than historical AC-resistant BC (2–7%), showing that cTCH (pCR rate 67%) or nab-TCH (pCR rate 32%) are effective in AC-resistant HER2+BC. The addition of bevacizumab did not achieve a higher pCR rate compared to prior study in HER2-BC with cTC. No significant financial relationships to disclose.
Relationship between interleukin-6 spillover in the lungs and pulmonary vascular resistance in patients with congestive heart failure Naoko Mabuchi, Takayoshi Tsutamoto, Atsuyuki Wada, Keiko Maeda, Masaru Hayashi, Takashi Tsutsui, Masato Ohnishi, Masahide Sawaki, Masanori Fujii, Takehiro Matsumoto, Takashi Yamomoto. Shiga University of Medical Science, Otsu, Japan
Journal: Journal of the American College of Cardiology (2001)
THE MEDICAL ASPECTS OF CRIME PREVENTION.
Journal: JAMA (1892)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE BUSY PRACTITIONER AND HIS OPPORTUNITIES.
Journal: JAMA (1903)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Incorrect Number
Journal: JAMA (1990)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Contraceptives and Hypertension
Journal: JAMA (1970)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
EXTRAMEDULLARY HEMATOPOIESIS IN MAN
Journal: JAMA (1934)

One of the most striking examples of the "safety devices" for insuring the adequate functioning of vital tissues in times of stress is the protective mechanism that operates to maintain a sufficient quantity of circulating red blood cells. A sudden loss of blood, for example, is compensated for by the rapid release from the bone marrow of immature erythrocytes, by the reticulocytes, and by an outpouring of stored red cells from certain reservoirs. If the blood loss is more severe or prolonged, the erythrogenic marrow itself may hypertrophy within its bony casing, more or less completely replacing the fatty marrow within a short time. Spicules of bone or even the inner portions of the bone shaft may disappear, apparently to provide additional space for the expanding red marrow. If these adjustments still fail to meet the demand for increased erythrogenesis, blood production in other tissues may take place. The phenomenon