tbuckley/cabot-search huggingface dataset:
How well does the activated partial thromboplastin time predict postoperative hemorrhage?
Authors: A. L. Suchman
Journal: JAMA (1986)

To determine the clinical usefulness of the activated partial thromboplastin time in screening patients before surgery, we related preoperative test results to the occurrence of hemorrhagic complications, studying all adult inpatients undergoing invasive diagnostic or therapeutic procedures at a large university hospital during a one-year period. Using clinical characteristics to divide the population into two groups according to a priori risk of hemorrhagic complications, we found that the activated partial thromboplastin time had no ability to predict the occurrence or absence of hemorrhage in the low-risk group, but that it was a predictor of modest strength in the high-risk group. Our data justify limiting preoperative coagulation screening to patients with active bleeding, known or clinically suspected bleeding disorders (including use of anticoagulants), liver disease, malabsorption, malnutrition, or other conditions associated with acquired coagulopathies and patients whose procedures may interfere with normal coagulation. (<i>JAMA</i>1986;256:750-753)
ERRATUM
Journal: Journal of Clinical Oncology (2004)

contained three errors.A sentence in the second column and first full paragraph of page 2779 mistakenly reads, "Interestingly, the median survival time (34 months) in our study was similar to that from preoperative chemoradiotherapy (35 months)."The corrected sentence should read, "Interestingly, the median survival time (34 months) in our study was similar to that from postoperative chemoradiotherapy (35 months)."The legend for Figure 2 should read, "Fig 2 .Kaplan-Meier survival plot according to type of pathologic response after surgery for 28 explored patients.Median survival time, 64 months for patients with pathologic response and 12.6 months for patients with no pathologic response."The legend for Figure 3 should read, "Fig 3 .Kaplan-Meier disease-free survival plot according to type of pathologic response after surgery for 28 explored patients.Median disease-free survival time, 46 months for patients with pathologic response and 5 months for patients with no pathologic response."
Morphine for Dyspnea in Patients with Cancer
Authors: Eduardo Bruera
Journal: Annals of Internal Medicine (1994)

Letters15 April 1994Morphine for Dyspnea in Patients with CancerEduardo Bruera, MD and Robin L. Fainsinger, MBChBEduardo Bruera, MDUniversity of Alberta; Edmonton, Alberta T5K OL4; CanadaSearch for more papers by this author and Robin L. Fainsinger, MBChBUniversity of Alberta; Edmonton, Alberta T5K OL4; CanadaSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-120-8-199404150-00017 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:We read with interest the letter by Krasnow and colleagues. Differences in results of pulse oximetry [1] and end-tidal CO2[2] after an increase of 50% in the analgesic dose of morphine may be due to differences in patient population or, more likely, to the mode of administration of morphine (intermittent injection compared with continuous infusion). Although some patients present with continuous dyspnea, most experience wide diurnal variations in the intensity of their dyspnea. The use of continuous opiates presents the same problems as that observed in the management of incident pain [3]: excessive dose when the symptom intensity ...References1. Bruera E, MacEachern T, Ripamonti C, Hanson J. Subcutaneous morphine for dyspnea in cancer patients. Ann Intern Med. 1993; 119:906-7. Google Scholar2. Bruera E, Macmillan K, Pither J, MacDonald RN. The effects of morphine on the dyspnea of terminal cancer patients. Journal of Pain and Symptom Management. 1990; 5:341-4. Google Scholar3. Portenoy RK, Hagen NA. Breakthrough pain: definition, prevalence and characteristics. Pain. 1990; 41:273-81. Google Scholar4. Bruera E, Ripamonti C, Brennels C, Macmillan K, Hanson J. A randomized double-blind crossover trial of intravenous lidocaine in the treatment of neuropathic cancer pain. Journal of Pain and Symptom Management. 1992; 7:138-40. Google Scholar5. Fainsinger RL, MacEachern T, Miller MJ, Bruera E, Spachynski K, Kuehn N, et al. The use of hypodermoclysis (HDC) for rehydration in terminally ill cancer patients. Journal of Pain and Symptom Management. 1994; (In press). Google Scholar Author, Article, and Disclosure InformationAffiliations: University of Alberta; Edmonton, Alberta T5K OL4; Canada PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 15 April 1994Volume 120, Issue 8Page: 692-693KeywordsAnalgesicsDyspneaMorphineOpiatesOpioidsPain managementPulse oximetry ePublished: 15 August 2000 Issue Published: 15 April 1994 Copyright & PermissionsCopyright © 1994 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
International Medical Education
Journal: JAMA (1972)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Ninth Annual Symposium for Referring Physicians
Journal: JNCI Journal of the National Cancer Institute (1974)

Journal Article Ninth Annual Symposium for Referring Physicians Get access JNCI: Journal of the National Cancer Institute, Volume 53, Issue 6, December 1974, Page 1881, https://doi.org/10.1093/jnci/53.6.1881-a Published: 01 December 1974
The Cover
Authors: Hubert R. Catchpole
Journal: JAMA (1987)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
BOOK REVIEWS
Authors: F. CABANILLAS
Journal: JNCI Journal of the National Cancer Institute (1991)

Journal Article BOOK REVIEWS Get access Malignant Lymphoma: Biology, Natural History, and Treatment Alan C. AisenbergPhiladelphia: Lea & Febiger , 1991 . xiv, 395 pp., illus. $54.50. FERNANDO CABANILLAS FERNANDO CABANILLAS The University of Texas M.D. Anderson Cancer Center1515 Holcombe Blvd. Houston, TX 77030 Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 83, Issue 23, 4 December 1991, Pages 1757–1758, https://doi.org/10.1093/jnci/83.23.1757-a Published: 04 December 1991
Death and Sudden Death.
Journal: JAMA (1902)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Influence of Direction of Aortic Perfusion on Regional Blood Flow
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Obstetrics and gynecology
Authors: G. R. Huggins
Journal: JAMA (1989)

During the past several years, exciting and significant advances have been made in the field of antenatal diagnosis with the development of percutaneous blood sampling and chorionic villus sampling. Percutaneous umbilical blood sampling provides direct access to fetal circulation in the second and third trimesters of pregnancy.<sup>1,2</sup>This technique allows a much more rapid diagnosis of chromosomal abnormalities in the second trimester: results are now possible within 72 hours as opposed to the several weeks required by traditional amniocentesis. This new technique has been useful in diagnosing fetal hematologic disorders and has proved to be helpful in the diagnosis and management of nonimmune fetal hydrops and isoimmune disorders. The fetal hemoglobin level measured directly is a much more reliable parameter for determining the necessity for intrauterine transfusions in rhesus isoimmunization than our traditional indirect parameters, such as bilirubin levels in amniotic fluid. Preliminary studies suggest that this technique might
Correction
Journal: Circulation (2008)

several errors occurred.In the Figure 6 legend, starting 12 lines from the top, the wrong color arrows are indicated.The text should read " . . .endothelial cells (green arrows) and smooth muscle cells (SMC) in the media (blue arrows)."On the same page, left column, ninth line from the top, the callout for Figure 7C should read, "Figure 7C, top middle, asterisk" rather than "Figure 7C, bottom left, asterisk."In the Figure 7 legend, 9 lines from the top, the sentence should begin, "The lower middle image shows . . ." rather than "These lower middle images show . . .."In the Figure 8 legend, the wording for panel C was incomplete.It should read, "C, TUNEL (red), DAPI (blue), macrophage (brown), and SMC (brown) staining of lesions similar to those in B." Also in the Figure 8 legend, the following sentence, currently located toward the end of the legend, should have appeared with the description of panel B: "Total lesion area was 493.7Ϯ40.5 and 380.6Ϯ24.4m 2 in Stat1 ϩ/ϩ 3 Ldlr Ϫ/Ϫ and Stat1 Ϫ/Ϫ 3 Ldlr Ϫ/Ϫ mice, respectively."
Qualitative study of patients’ and family caregivers’ (FC) perceptions and information preferences about hospice.
Authors: Areej El-Jawahri, Jennifer Shin, Lara Traeger, Helen Knight, Joel Nathan Fishbein, Harry VanDusen, Tanya Keenan, Vicki A. Jackson, Angelo E. Volandes, Jennifer S. Temel
Journal: Journal of Clinical Oncology (2015)

e20501 Background: Despite the benefits of hospice for patients with advanced cancer and their FC, many patients are referred late or not at all. To assess potential patient and FC barriers to enrollment, we assessed their perceptions, knowledge, and information preferences about hospice. Methods: We conducted qualitative interviews with 16 adult patients with metastatic cancer and a prognosis ≤ 12 months and 8 of their FC. We used a semi-structured interview guide to elicit their perceptions (including perceived barriers to utilization), knowledge, and information preferences about hospice. Two raters coded interviews independently and reached acceptable inter-rater reliability (κ > 0.85). We used content analysis to identify themes. Results: We found similar themes between patients and FC interviews. Participants had mixed views about which patients need hospice with some stating it is for patients only at the end-of-life and others perceiving it as important for patients who need care their family cannot provide. Notably, most patients perceived themselves as not needing hospice in the near future. While the majority perceived the role of hospice to enhance quality of life and provide comfort, some viewed it as providing practical support, including 24-hour care. 50% of participants had positive feelings about hospice, while others were more ambivalent. All participants felt they needed more information about hospice, yet they were mixed regarding the optimal timing of this information. Many thought it would be helpful to have information about hospice through pamphlets, websites, or videos, prior to a discussion with their oncologist. Most viewed denial and hope as the main barriers to early hospice enrollment. Conclusions: Study participants had misunderstandings about which patients were appropriate for hospice and regarding the services offered. Participants expressed strong desires for more information about hospice with educational tools, although were mixed about the optimal timing for reviewing these tools. These findings suggest that patients and FC would benefit from interventions to enhance their understanding of hospice and to facilitate a discussion with their oncologists.
THE HUNT MEMORIAL.
Journal: JAMA (1898)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
PHASES OF "CHRISTIAN SCIENCE."
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The distribution of euthyroid serum protein-bound iodine levels
Authors: J. C. Nelson
Journal: JAMA (1971)

The dispersion of serum protein-bound iodine levels in euthyroid subjects does not allow a normal curve of distribution. Therefore, the mean ± 2 standard deviations does not define the central 95% of a "normal" population for this test. The logarithmic transformation provides a reasonably good fit to the normal distribution curve and allows the calculation of the central 95% of the values. In this study the limits of the central 95% of values were 3.4 to 8.2μg/100 ml.
HALLUCINOGENIC AGENTS
Authors: Dana L. Farnsworth
Journal: JAMA (1963)

An article on stramonium intoxication in this issue ofThe Journal(p 882) calls attention to a growing medical and social problem in this country—the ingestion of a number of drugs which have the common property of drastically altering sensory perception. The drugs all produce hallucinations. In addition to stramonium, the drugs include mescaline or peyote, lysergic acid diethylamide (LSD-25), psilocybin, marijuana, and, as a recent addition, morning-glory seeds (<i>Rivea corymbosa</i>). The morning-glory seeds contain amides of lysergic acid. General public interest in these psychotomimetic drugs is now on the increase in many parts of the United States. Use of the drugs to produce hallucinations goes back for centuries, but in recent years we have discovered new forms of these hallucinogens; and we have witnessed the development of a new and subtle promotion designed to interest the general public in trying them out. The promotion of the drugs is having
An outbreak of a newly recognized chronic diarrhea syndrome associated with raw milk consumption
Authors: M. T. Osterholm
Journal: JAMA (1986)

A previously undescribed chronic diarrhea syndrome affected 122 residents of Brainerd, Minn, between December 1983 and July 1984. The illness lasted at least one year for 75% of case-patients and was characterized by acute onset, marked urgency, a lack of systemic symptoms, and a failure of response to antimicrobial agents. Clinical and laboratory data indicate that the diarrhea was caused by a secretory mechanism. Consumption of raw milk from a single dairy was associated with illness (odds ratio, 28.3; 95% confidence interval, 9.0 to 89.0). A median incubation period of 15 days was determined for seven case-patients. Possible secondary transmission was noted in one family. Extensive laboratory examination did not identify an etiologic agent. Outbreaks or sporadic cases of a similar illness have occurred in at least seven states; the outbreaks were less extensively investigated and findings were not published, but raw milk consumption was common in the affected persons. This illness appears to represent a previously unrecognized but important clinical entity and public health problem. The etiology and effective therapy for this illness must be determined by further studies of sporadic cases and outbreaks. (<i>JAMA</i>1986;256:484-490)
Hormone replacement and breast cancer. A remaining controversy?
Authors: H. O. Adami
Journal: JAMA (1995)

Ever since replacement hormones were introduced some 30 years ago, there has been concern regarding a possible adverse effect on breast cancer risk. More than 30 epidemiological studies have explored the relationship between exogenous hormones and breast cancer. Most of them were of case-control design,<sup>1-3</sup>while seven were prospective cohort studies.<sup>4-10</sup>Despite several attempts to summarize available evidence in overviews<sup>1</sup>and through meta-analyses,<sup>2,3</sup>there is still considerable uncertainty as to whether replacement hormones increase breast cancer risk. However, some recent studies indicate that long-term intake of conjugated estrogens or estradiol compounds is associated with a moderate risk increase.<sup>6,8,11-13</sup>The remaining controversy might be viewed as a shortcoming of the epidemiological method, ie, inability to clarify the role of a potential cause of breast cancer. According to a rival and more optimistic interpretation, the absence of unequivocal evidence for a risk-increasing effect of replacement hormones indicates
PROFESSIONAL RESPONSIBILITIES.
Authors: A. E. BALDWIN
Journal: JAMA (1904)

While this is a hackneyed subject, it is one on which we ought to devote a great deal of thought. We stand before the public and the general profession as the guardians of the entrance to the alimentary canal, and these responsibilities laid on us determine many things in connection with the general health of our patrons. I am not unmindful that while we occupy a very limited field as to the actual work which we do, the far-reaching effect of the work, or lack of it, is easily demonstrable. It seems to me that we fall short of a just and broad comprehension of our responsibilities in many instances. These responsibilities begin in our advising our patrons as to the care and carefulness with which the temporary teeth of the little ones should be protected, as well as advising as to the care of the permanent teeth which obtain
TCT-402 The Efficacy of a "Reversed Wire Technique" for Treating Bifurcation Lesions in Percutaneous Coronary Intervention -"Tips &amp; Tricks" for salvaging the side branch -
Authors: Masashi Kimura, Yasushi Asakura, Yoshihisa Kinoshita, Tetsuo Matsubara, Kenya Nasu, Takahiko Suzuki, Tomohiko Teramoto, Etsuo Tsuchikane
Journal: Journal of the American College of Cardiology (2013)