tbuckley/cabot-search huggingface dataset:
Nature and Health. A Popular Treatise on the Hygiene of the Person and the Home.
Journal: JAMA (1907)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
What's new in the other general journals
Authors: Alison Tonks
Journal: BMJ (2006)

It's been clear for a long time that men and women experience pain differently. Women get painful conditions such as fibromyalgia more often than men and are much more likely consult a doctor when they do, for example. Until recently, doctors tended to undertreat or even dismiss women's pain, putting women's complaining down to a lack of moral fibre or to emotion. But a recent review of pain research finds mounting evidence that women feel pain differently from men because they have different neurophysiology (moderated by different receptors) and different neurochemicals. Scientists have already found one gene that modulates pain in women but not men—the melanocortin-1 receptor gene, which is linked to red hair and fair skin. Credit: JAMA Experiments in functional brain imaging are also emerging, showing that pain activates different areas of the brain in men and women. This has knock-on effects on the system generating endogenous opioids. Credit: N ENGL J MED These issues are not simply academic. One fifth of medical consultations are about pain, and a tenth of all sales of prescription drugs are for pain relief. The review argues that if scientists could unravel sex differences in pain processing, then the path would be clear for drug companies to develop analgesics specifically for men or women, improving pain relief. Ann Intern Med 2006;144: 461–4 [OpenUrl][1][CrossRef][2][PubMed][3] Doctors should think carefully before prescribing telithromycin, say authors from North Carolina who report three cases of massive hepatic necrosis in fit people taking the drug. Only one patient recovered spontaneously. A 26 year old man died of liver failure, and the remaining patient, a 51 year old woman, survived after a liver transplant operation. Telithromycin is the first in a new class of antibiotic. It was developed to overcome macrolide resistance and is licensed in the US for common primary care infections such as … [1]: {openurl}?query=rft.jtitle%253DAnnals%2Bof%2BInternal%2BMedicine%26rft.stitle%253DANN%2BINTERN%2BMED%26rft.issn%253D0003-4819%26rft.aulast%253DWilson%26rft.auinit1%253DJ.%2BF.%26rft.volume%253D144%26rft.issue%253D6%26rft.spage%253D461%26rft.epage%253D464%26rft.atitle%253DThe%2Bpain%2Bdivide%2Bbetween%2Bmen%2Band%2Bwomen.%26rft_id%253Dinfo%253Adoi%252F10.7326%252F0003-4819-144-6-200603210-00031%26rft_id%253Dinfo%253Apmid%252F16549870%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/external-ref?access_num=10.7326/0003-4819-144-6-200603210-00031&link_type=DOI [3]: /lookup/external-ref?access_num=16549870&link_type=MED&atom=%2Fbmj%2F332%2F7544%2F781.atom
Selected New Books
Journal: JAMA (1974)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Effect of Enzyme Induction on Nephrotoxicity of Halothane-Related Compounds
Authors: Ben A. Hitt, Richard I. Mazze
Journal: Environmental Health Perspectives (1977)

Nephrotoxicity following administration of methoxyflurane has been shown to be directly related to anesthetic metabolism to inorganic fluoride. Enzyme induction should increase metabolic rate and the amount of inorganic fluoride that is released. In vivo studies in Fischer 344 rats show that enzyme induction with phenobarbital or phenytoin increases defluorination following methoxyflurane anesthesia but not after enflurane or isoflurane. In vitro, methoxyflurane defluorinase activity was increased far more than that of any of the other anesthetics. These data suggest that treatment with enzyme inducing drugs increases the risk of nephrotoxocity only if methoxyflurane is the anesthetic agent.
The Permanent Secretary Explains.
Journal: JAMA (1898)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Book Reviews
Authors: Chiara Ruini, Fedra Ottolini, Chiara Rafanelli, Eliana Tossani, Carol D. Ryff, Giovanni A. Fava, Peter Henningsen, Stefan Priebe, Gabriella Franca Milos, Anja Margareta Spindler, Claus Buddeberg, Aureliano Crameri, Carlos Schönfeldt-Lecuona, Bernhard J. Connemann, Manfred Spitzer, Uwe Herwig, Leo Sher, Moniek S.E. van Hout, Ellie M. Wekking, Ina J. Berg, Betto G. Deelman, Kav Vedhara, Paul D. Bennett, Sian Clark, Stafford L. Lightman, Samantha Shaw, Paula Perks, Moira A. Hunt, Judith M.D. Philip, Deborah Tallon, Peter J. Murphy, Roy W. Jones, Gordon K. Wilcock, Nola M. Shanks, Cristina Fortes, Sara Farchi, Francesco Forastiere, Nera Agabiti, Roberta Pacifici, Piergiorgio Zuccaro, Carlo A. Perucci, Shah Ebrahim, Lisa Terre, Walker S. Carlos Poston, John Foreyt, Sachiko T. St. Jeor
Journal: Psychotherapy and Psychosomatics (2003)
Personal View
Authors: D. Summerfield
Journal: BMJ (1993)

<h3>Background</h3> The District Health Information System 2 (DHIS2) is a tool for collection, validation, analysis and presentation of both individual (tracker) and aggregated data tailored to integrated health information management activities. DHIS2, developed by the Health Information Systems Programme (HISP) in collaboration with University of Oslo, is a modular web-based software package built with open source Java frameworks. Visceral leishmaniasis (VL) is not captured in the DHIS2 regional database, and therefore coming up with the modalities of aggregating available data from clinical trials and general patient records into the DHIS2 national database is crucial for surveillance. <h3>Methods</h3> DHIS2 runs on Tomcat Server and PostgreSQL. We set up the VL surveillance program with different stages: enrolment and demographics, initial treatment outcome and follow-up visits. In this system, a patient is enrolled into the system and data is collected in individual data elements; data Indicators are built to help aggregate the data and thereafter used for report generation. It is programmed to visualise data and display reports in the system dashboard which can then be used to present data. <h3>Results</h3> Piloting DHIS2 has enabled us to set up a system that uses the set indicators programmed to aggregate data, thus able to produce reports on the data and the user is also able to select the type of report in the form of pivot tables, charts and graphs and also in GIS mapped data. <h3>Conclusions</h3> DHIS2 system is an open source that can be customised and expanded to capture detailed individual surveillance data and shared in reports. This data is useful for tracking neglected tropical diseases such as VL. Data can be handled in the following modalities: i) use of off-line data synchronisation. ii) remote data collection using mobile devices iii) data aggregation and organisation iv) data visualisation and presentation through charts, graphs and pivot tables.
Leading cases
Authors: B. Nortell
Journal: JAMA (1977)

EVERY week there are many court decisions that have an impact on the practice of medicine. These decisions are currently reported, in summary, in<i>The Citation</i>, a newsletter published twice a month by the office of the General Counsel, American Medical Association. Some of these decisions are of such special importance that they deserve the wider publicity that can be obtained through the pages ofThe Journal. Trial court decisions, which are of little precedent value and are subject to reversal, are omitted. Selected decisions are usually restricted to those of the highest state or federal court. It should be remembered, however, that a decision by a court in one state is not necessarily binding elsewhere. <h3>Administrative Professional Services</h3> The professional services of a physician may include administrative activities, the Wisconsin Supreme Court has ruled.<sup>1</sup>This is an important decision because a physician may wish to bring suit to
Patient centred care produced greater satisfaction but less knowledge
Journal: BMJ (1998)

Terms used to describe trials may have different meanings for patientsLittle is known about patients' perspectives of participation in randomised controlled trials.On p 1177 Featherstone and Donovan explore the understandings of randomisation among middle aged and elderly men participating in a trial of treatments for benign prostatic disease.Most men were able to recall and describe basic aspects of randomisation such as the involvement of chance, but they also developed alternative accounts to help them make sense of their experiences.The use of terms with different meanings for patients and trialists (such as "trial") caused confusion, as did inaccuracies in patient information.Providing clear and accurate patient information is crucial, and patients need to be able to discuss their concerns about concepts such as randomisation if they are to give truly informed consent to participate in randomised controlled trials.
Death during jogging or running. A study of 18 cases
Authors: P. D. Thompson
Journal: JAMA (1979)

We investigated the circumstances of death and the medical and activity histories of 18 individuals who died during or immediately after jogging. Thirteen men died of coronary heart disease (CHD) and four men and one woman died of other causes. Six CHD subjects had medical histories relevant to the cardiovascular system, but only one had diagnosed CHD. Six CHD subjects experienced prodromal symptoms but continued vigorous exercise programs. Two subjects had exercised less than a month, but most had trained regularly for years. The CHD risk factors for the CHD cases did not differ significantly from those for other age-matched, physically active men. Superior physical fitness does not guarantee protection against exercise deaths. Physicians and exercising adults should be aware of this fact and give appropriate attention to possible prodromal symptoms. (<i>JAMA</i>242:1265-1267, 1979)
Transmission of genital herpes by donor insemination
Authors: D. E. Moore
Journal: JAMA (1989)

This report describes a donor in a therapeutic donor insemination program who asymptomatically acquired a primary herpes simplex virus type 2 (HSV-2) infection from his long-standing sexual partner. His fresh semen was used to inseminate two HSV-seronegative recipients; in one a primary HSV-2 infection developed, and in one it did not. Direct evidence of transmission from donor to recipient was documented by restriction enzyme analysis of the HSV-2 isolates obtained from the donor's semen and from the recipient's cervix. Because of the possibility of asymptomatic acquisition and transmission of HSV-2, semen donors and their sexual partners should undergo serologic screening for genital herpes using new, type-specific HSV serologic techniques. (<i>JAMA</i>. 1989;261:3441-3443)
The Pathology of the Eye.
Journal: JAMA (1905)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Geriatric medicine
Authors: L. Z. Rubenstein
Journal: JAMA (1990)

The dramatic growth in geriatric medicine over the past decade stems from a convergence of several forces, the most prominent of which is the rapid expansion in numbers and political clout of the elderly population, together with their rising expectations and their impatience with the current health care system. The medical profession, along with other health professionals, has responded with a surge of interest, research, creative publishing, and training programs in the gerontologic fields. The recent establishment of a certifying examination in geriatrics (Certificate of Added Qualifications in Geriatric Medicine), jointly sponsored by the American boards of both internal medicine and family practice (and passed by over 2400 physicians in the first round), and the recent decision by the Accreditation Council of Graduate Medical Education to accredit the growing number of fellowship programs in geriatrics have solidified this professional expansion. Physician interest in geriatrics will probably expand further with the
Therapeutic Priorities
Authors: C. D. Needham
Journal: BMJ (1968)

<h3>Abstract</h3> The epithelial and interstitial stem cells of the freshwater polyp <i>Hydra</i> are the best characterized stem cell systems in any cnidarian, providing valuable insight into cell type evolution and the origin of stemness in animals. However, little is known about the transcriptional regulatory mechanisms that determine how these stem cells are maintained and how they give rise to their diverse differentiated progeny. To address such questions, a thorough understanding of transcriptional regulation in <i>Hydra</i> is needed. To this end, we generated extensive new resources for characterizing transcriptional regulation in <i>Hydra</i>, including new genome assemblies for <i>Hydra oligactis</i> and the AEP strain of <i>Hydra vulgaris</i>, an updated whole-animal single-cell RNA-seq atlas, and genome-wide maps of chromatin interactions, chromatin accessibility, sequence conservation, and histone modifications. These data revealed the existence of large chromatin interaction domains in the <i>Hydra</i> genome that likely influence transcriptional regulation in a manner distinct from topologically associating domains in bilaterians. We also uncovered the transcriptomic profiles of two previously molecularly uncharacterized cell types, isorhiza-containing nematocytes and somatic gonad ectoderm. We identified novel candidate regulators of cell-type-specific transcription, several of which have likely been conserved at least since the divergence of <i>Hydra</i> and the jellyfish <i>Clytia hemisphaerica</i> over 200 million years ago. The resources generated in this study, which collectively represent the most comprehensive characterization of transcriptional regulation in a cnidarian to date, are accessible through a newly created genome portal, available at research.nhgri.nih.gov/HydraAEP/.
Diagnosis-related groups and severity. ICD-9-CM, the real problem
Authors: R. L. Mullin
Journal: JAMA (1985)

A GREAT deal has been written in the medical literature, the hospital industry literature, and the press about the insensitivity of the diagnosis-related groups (DRGs) to severity of illness.<sup>1</sup>This statement has even come from the Congress of the United States. <h3>Medisgrps Severity Classification</h3> An article titled "Review System Based on Illness Severity" recently appeared in<i>American Medical News</i>.<sup>2</sup>It describes the Medisgrps severity classification definitions. The article states: "At admission, Medisgrps assigns a patient to one of five severity groups, and then compares that severity with severity at a later date, typically 10 days after admission or six days after surgery." Since the average length of stay of Medicare patients is now under 8.8 days and non-Medicare patients under 5.6 days, a majority of the patients will be discharged before this second severity assignment. The table concerning DRG 122 appearing in the article is reproduced herein, with
Intraperitoneal Hemorrhage due to Uterine Fibroid
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
AIR POLLUTION AND URBAN MORBIDITY
Journal: JAMA (1966)

The effect on health and disease of substances polluting the urban air is difficult to assess. Despite many epidemiological surveys, it is not known whether particulates and gaseous pollutants are harmful in the concentrations in which they are frequently found, whether they cause specific diseases, or if they exert a differential effect which may increase reactions to some diseases more than others. It is possible, however, to observe acute effects, possibly induced by small changes in air-pollution levels, in a population temporarily at a low level of tolerance—hospitalized patients. The hospitalized person is in the physical condition most likely to be influenced by additional stresses. Also, reliable measures of increased morbidity can be obtained relatively easily. Of a number of measures of prevalence and severity of morbidity, hospital admissions and the length of stay may be the most available. Although factors other than the clinical state of the disease operate
First three patients for new type of implantable cardioverter
Journal: JAMA (1983)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal