tbuckley/cabot-search huggingface dataset:
State Board Results in the Educational Number.
Journal: JAMA (1906)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Role of the Physician in Driver Licensing
Journal: JAMA (1968)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Knowing HIV Status Crucial in Cancer Treatment
Journal: JAMA (2015)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Transfusion of Blood
Journal: JAMA (2015)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Gonorrhea screening in male consorts of women with pelvic infection
Authors: L. C. Gilstrap
Journal: JAMA (1977)

<i>Neisseria gonorrhoeae</i>was isolated from 39% of male contacts of women with acute gonococcal pelvic inflammatory disease (PID); 22% of these men were asymptomatic. More than half of those women with gonococcal PID had at least one male sexual consort with gonorrhea.<i>Neisseria gonorrhoeae</i>was isolated from 15% of male contacts of women with nongonococcal PID; 30% were asymptomatic. Since a substantial number of male contacts of women with acute PID will have cultures positive for<i>N gonorrhoeae</i>and are asymptomatic, all male sexual consorts should be examined and have cultures grown for gonorrhea. (<i>JAMA</i>238:965-966, 1977)
Current Comment
Journal: JAMA (1942)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
INFORMATION ON EFFECTS OF WAR GASES
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Billie Belle
Authors: Paul Rousseau
Journal: Annals of Internal Medicine (2001)

Letters15 May 2001Billie BellePaul Rousseau, MDPaul Rousseau, MDVeterans Affairs Medical Center; Glendale, AZ 85310 (Rousseau)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-134-10-200105150-00019 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:I applaud Dr. Williams's poignant essay, “Billie Belle's Unkind Death” (1) and agree with him about the paucity of physician empathy, compassion, and caring in a high-technology medical environment. However, I fear that Dr. Williams's comments on Billie Belle's experience with hospice care will alienate physicians, many of whom already perceive hospice as a “touchy-feely” type of care without any real scientific basis or value (an appraisal that lacks merit). I am bewildered as to why Billie Belle's son had to go to a hospital pharmacy to pick up necessary medications (thus missing his mother's death)—hospice programs ...References1. Williams MK. Billie Belle's unkind death. Ann Intern Med. 2000;133:743-4. [PMID: 0011074910] LinkGoogle Scholar2. Peabody FW. The care of the patient. JAMA. 1927;88:877-82. CrossrefGoogle Scholar Author, Article, and Disclosure InformationAuthors: Paul Rousseau, MDAffiliations: Veterans Affairs Medical Center; Glendale, AZ 85310 (Rousseau) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoBillie Belle's Unkind Death Michael K. Williams Regarding the Unkind Death of Billie Belle Michael K. Williams Metrics Cited byRegarding the Unkind Death of Billie BelleMichael K. Williams, MD 15 May 2001Volume 134, Issue 10Page: 1009KeywordsEmotionsEnd of life careFearOpioidsPatients ePublished: 15 May 2001 Issue Published: 15 May 2001 Copyright & PermissionsCopyright © 2001 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Posters
Authors: S. Ranta, N. Svartling, J. Vuola, O. Takkunen, V. A. Alyoshkin, L. I. Novikova, V. B. Hvatov, T. A. Ivanina, E. A. Evteeva, E. R. Gomes, H. S. Machado, A. Paiva, R. Araújo, A. M. Carneiro, A. Stokić, V. Peković, J. Belopavlović, E. Stokić, M. Tatić, T. Radunović, B. Draŝković, A. Muñoz Sanchez, P. I. Jimenez, F. Hernández, F. Murillo Cabezas, R. Rosero, A. Caravallo, O. G. Phomkin, V. D. Slepushkin, E. U. Pronichev
Journal: Intensive Care Medicine (1996)
Editorial: Peyote (mescaline) and human chromosomes
Authors: A. D. Bloom
Journal: JAMA (1975)

Given the controversy of the late 1960s and early 1970s over the possible induction of chromosomal damage by psycho-active agents like LSD and marihuana, the peyote study of Teplitz et al (p 299), is reassuring. It is, first of all, comforting to know that in vivo studies of agents that are possible chromosomal mutagens can produce, when properly designed and executed, clear-cut results. Second, it is nice to know that these results can sometimes be negative. The authors have not demonstrated any increase in chromosomal aberrations in the peripheral-blood lymphocytes of the Huichol Indians of northern Mexico, lifelong users of the hallucinogen peyote, a mescaline-containing cactus. (We may now only hope that there will be no mad rush, among our younger generation in particular, to experiment more heavily with peyote or with the chemically purer mescaline by dint of this apparent absence of chromosomal effects.) One of the major questions
#3539 NARROW BAND IMAGING WITH HIGH RESOLUTION BRONCHOVIDEOSCOPE: A NEW APPROACH TO VISUALISE ANGIOGENESIS IN SQUAMOUS CELL CARCINOMA OF THE LUNG
Authors: K Shibuya, T Nakajima, K Yasufuku, A Iyoda, M Suzuki, Y Sekine, T Iizasa, K Hiroshima
Journal: Journal of Thoracic Oncology (2007)
Immune response of peripheral blood mononuclear cells to HBx-antigen of hepatitis B virus
Authors: M Jung
Journal: Hepatology (1991)

The hepatitis B virus genome encodes a transcriptional transactivator protein designated HBxAg. We have investigated whether this antigen is a target structure for human T-lymphocytes. Using recombinant HBxAg protein, we found HBxAg-specific stimulation of peripheral blood mononuclear cells in patients with acute hepatitis B virus infection (6 of 6) and chronic hepatitis B virus infection (6 of 17) but not in healthy individuals. With HBxAg-specific synthetic polypeptides, several T-cell epitopes were identified. Most were located in the carboxyterminal half of the HBxAg protein. Five T-cell clones specific for a T-cell epitope located at the carboxyterminal region of HBxAg were established and found to belong to the CD2/CD4-positive, CD8-negative subtype. These data establish for the first time HBxAg as an antigen in the cellular immune response. (HEPATOLOGY 1991;13:63–643.)
The Elements of Vital Statistics in Their Bearing on Social and Public Health Problems.
Journal: JAMA (1924)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Zomepirac-induced serum sickness. A report of two cases
Authors: R. Kiani
Journal: JAMA (1983)

Two patients, after several weeks of zomepirac sodium use, experienced acute toxic eruption, fever, lymphadenopathy, arthralgias, angioedema of the hands, and eosinophilia. We believe that these cases represent type 3 allergic reactions to zomepirac. (<i>JAMA</i>1983;249:2812-2813)
Abstract 11808: Association Between Left Ventricular Properties in Patients With Hypertension and the Incidence of Paroxysmal Atrial Fibrillation: Three-Dimensional Speckle Tracking Echocardiographic Study
Authors: Masafumi Kawade, Masanori Kawasaki, Shingo Minatoguchi, Ryuhei Tanaka, Maya Ishiguro, Noriaki Sato, Maki Nagaya, Mayumi Kaneda, Hiroto Yagasaki, Yoshiaki Goto, Makoto Iwama, Takeshi Hirose, Koji Ono, Masazumi Arai, Toshiyuki Noda, Sachiro Watanabe, Shinya Minatoguchi
Journal: Circulation (2014)

Background: Hypertension (HTN) is one of the major causes of atrial fibrillation (AF), since it is usually accompanied by left atrial (LA) remodeling due to pressure and/or volume (LAV) overload. We examined the relationship between ventricular (LV) geometry or LV properties in HTN and the incidence of paroxysmal AF (PAF) using novel, one-beat, automated, 3-dimensional speckle tacking echocardiography (3D-STE) with high volume rates. Methods: Patients with HTN (n=107, age 69±7) and controls (n=60, age 69±9) were prospectively enrolled. HTN patients were divided into 5 groups according to LV geometry and the presence of hypertensive heat failure (HHF) {normal geometry (n=25), concentric remodeling (n=20), concentric hypertrophy (LVH) (n=24), eccentric LVH (n=21) and HHF (n=17)}. Isovolumic relaxation time (IVRT) was measured by Doppler echo. We evaluated LV ejection fraction (EF), E/e’, pulmonary capillary wedge pressure (PCWP), Tau, LV diastolic stress, LV strain and LV myocardial stiffness in sinus rhythm. PCWP was estimated as 10.7- 12.4 x log (LA active emptying function / minimum LAV) as we reported. Tau was calculated as IVRT / (ln 0.9 x systolic blood pressure - ln PCWP). LV diastolic stress was calculated as LV radius at end diastole x PCWP / thickness. LV strain rate (SR) during IVR, as an index of relaxation, and LV strain were measured by the 3D-STE with volume rates of 50-80vps. LV myocardial stiffness was estimated as LV stress / LV strain. Results: LVEF was reduced only in HHF compared with controls (56±7 vs. 67±6%). Conclusion: LVEF in HHF was decreased but still remained within the normal range, whereas diastolic properties in eccentric LVH and HHF were reduced compared with control. The incidence of PAF significantly increased in eccentric LVH and HHF associated with the impairment of LV relaxation and stiffness and increased LV stress. This suggests that the target of treatment to reduce the incidence of PAF in HTN must be diastolic function.
Diagnosis and Treatment of Primary Aldosteronism
Authors: Jon D. Blumenfeld
Journal: Annals of Internal Medicine (1995)

Letters1 July 1995Diagnosis and Treatment of Primary AldosteronismJon D. Blumenfeld, MDJon D. Blumenfeld, MDThe New York Hospital-Cornell Medical Center; New York, NY 10021Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-123-1-199507010-00014 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:Rossi and colleagues raise several points about the preoperative diagnostic tests for primary aldosteronism discussed in our paper [1].Patients in our study were categorized as having an adenoma or nonadenomatous adrenal hyperplasia, according to whether an encapsulated adrenal tumor could be identified by the pathologist. Rossi and colleagues suggest that an occult microscopic adenoma may have been missed by CT scanning in the patients who were characterized as having nonadenomatous hyperplasia and that more sensitive imaging techniques may have identified these adenomas before surgery. Although possible, this scenario seems unlikely because we and others continue to identify ...REFERENCE1. Blumenfeld JD, Sealey JE, Schlussel Y, Vaughan ED Jr, Sos TA, Atlas TA, et al. Diagnosis and treatment of primary hyperaldosteronism. Ann Intern Med. 1994; 121:877-85. Google Scholar Author, Article, and Disclosure InformationAuthors: Jon D. Blumenfeld, MDAffiliations: The New York Hospital-Cornell Medical Center; New York, NY 10021 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byImpact of Accessory Hepatic Veins on Adrenal Vein Sampling for Identification of Surgically Curable Primary Aldosteronism 1 July 1995Volume 123, Issue 1Page: 73-74KeywordsAdenomasAdrenal tumorsAdrenalectomyComputed axial tomographyHypertensionImaging techniquesRadiologistsResearch laboratoriesSpecificitySurgery ePublished: 15 August 2000 Issue Published: 1 July 1995 Copyright & PermissionsCopyright © 1995 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Uncleaned anesthesia equipment
Authors: G. E. Dryden
Journal: JAMA (1975)

PAIN RELIEF and patient jeopardy are often partners when general anesthesia is administered through unclean equipment. A 1968 survey<sup>1</sup>of teaching hospitals disclosed that all parts of the anesthesia equipment were not being cleaned, even though cultures of the patient's exposed air passages were positive in many cases. There are scattered reports in the scientific literature proving the pathway of disease transmission from anesthesia equipment.<sup>2-4</sup>The morbidity and mortality statistics resulting directly from unclean anesthesia equipment have not been studied. However, the concept of aseptic technique in medical practice should be sufficient to induce the anesthesia teams to develop bacterially clean systems for each patient. The effectiveness of clean anesthesia systems for general anesthesia has been reported by Albrecht and Dryden,<sup>5</sup>who showed a decrease from 27% to 6% in the incidence of pulmonary complications when all parts of the anesthesia apparatus were cleaned after every use.
Skin lesions suspected to be melanoma should be photographed. Gross morphological features of primary melanoma associated with metastases
Authors: C. L. Day
Journal: JAMA (1982)

We reviewed photographs of 256 primary cutaneous melanomas to determine the gross morphological correlates of metastases. Seven and a half years after diagnosis, the melanomas with ulceration occupying at least 80% of their surface had the highest rate of metastases (85%), and melanomas without a nodule had the lowest metastatic rate (11%). Melanomas with nodules had a metastatic rate of 62%, and this rate increased in direct proportion to nodule diameter. Even after adjusting for nodule diameter and ulceration, melanomas with single nodules located completely within the confines of an associated plaque had half of the metastatic rate of melanomas with nodules located at the periphery (abutting normal skin). These data suggest that (1) carefully recorded gross pathological data can augment the microscopic pathological data in the determination of prognosis; (2) skin lesions suspected to be melanoma should be photographed; (3) the photograph, if followed by surgical removal of the lesion, should be attached to the pathology report in the patient's permanent medical record; (4) nodule diameter is better correlated with metastases than the total lesion diameter (as traditionally held); and (5) the cytologically malignant melanocytes that constitute the less-raised portion of most melanomas may not be biologically malignant, thus enlarging the precursor concept for malignant melanoma. The TNM staging system for malignant melanoma could be modified to incorporate these data. (<i>JAMA</i>1982;248:1077-1081)
In Brief
Journal: JAMA (1972)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal