Update in Cardiology
Authors: Joseph S. Alpert
Journal: Annals of Internal Medicine (1997)

Updates1 September 1997Update in CardiologyJoseph S. Alpert, MD and Howard R. Horn, MDJoseph S. Alpert, MD1997-98 Series.John Roberts, MD, Editor.From the University of Arizona Health Sciences Center, Tucson, Arizona, and the University of Tennessee, Memphis, Tennessee.Search for more papers by this author and Howard R. Horn, MD1997-98 Series.John Roberts, MD, Editor.From the University of Arizona Health Sciences Center, Tucson, Arizona, and the University of Tennessee, Memphis, Tennessee.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-127-5-199709010-00009 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Important advances made in the field of cardiology in the past year fall into three major disease categories, all of which are responsible for a disproportionate amount of death, disability, and cost in the United States and around the world. Congestive heart failure affects 1% of persons older than 65 years of age; acute coronary artery syndromes are the number one cause of death in the United States; and chronic coronary syndromes are increasingly responsible for hospitalizations, presumably because of the aging U.S. population and better survival after acute heart injuries.Congestive Heart FailureFive notable advances occurred in this ...References1. McKelvie RS, Teo KK, McCartney N, Humen D, Montague T, Yusuf S. Effects of exercise training in patients with congestive heart failure: a critical review. J Am Coll Cardiol. 1995; 25:789-96. Google Scholar2. Uretsky BF, Young JB, Shahid FE, Yellen LG, Harrison MC, Jolly MK. Randomized study assessing the effect of digoxin withdrawal in patients with mild to moderate congestive heart failure: results of the PROVED trial. J Am Coll Cardiol. 1993; 22:955-62. Google Scholar3. Packer M, Gheorghiade M, Young JB, Costantini PJ, Adams KF, Cody RJ, et al. Withdrawal of digoxir from patients with chronic heart failure treated with angiotensin-converting-enzyme inhibitors. RADIANCE Study. N Engl J Med. 1993; 329:1-7. Google Scholar4. Preliminary report: effect of encainide and flecainide on mortality in a randomized trial of arrhythmia suppression after myocardial infarction. The Cardiac Arrhythmia Suppression Trial (CAST) Investigators. N Engl J Med 1989; 321:406-12. Google Scholar5. Mittleman MA, Maclure M, Tofler GH, Sherwood JB, Goldberg RJ, Muller JE. Triggering of acute myocardial infarctior by heavy physical exertion. Protection against triggering by regular exertion. Determinants of Myocardial Infarction Onset Study Investigators. N Engl J Med. 1993; 329:1677-83. Google Scholar6. Mittleman MA, Maclure M, Sherwood JB, Mulry RP, Tofler GH, Jacobs SC, et al. Triggering of acute myocardial infarction onset by episodes of anger. Determinants of Myocardial Infarction Onset Study Investigators. Crculation. 1996; 92:1720-5. Google Scholar7. Hennekens CH, Buring JE, Manson JE, Stampfer M, Rosner B, Cook NR, et al. Lack of effect of long-term supplementation with β-carotene on the incidence of malignant neoplasms and cardiovascular disease. N Engl J Med. 1996; 334:1145-9. Google Scholar8. Sheffield JV, Larson EB. Update in general internal medicine. Ann Intern Med. 1997; 127:43-51. Google Scholar9. O'Neill W, Timmis GC, Bourdillon PD, Lai P, Ganghadarhan V, Walton J Jr, et al. A prospective randomized clinical trial of intracoronary streptokinase versus coronary angioplasty for acute myocardial infarction. N Engl J Med. 1986; 314:812-8. Google Scholar10. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet. 1994; 344:1383-9. Google Scholar11. Shepherd J, Cobbe SM, Ford I, Isles CG, Lorimer AR, MacFarlane PW, et al. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study. N Engl J Med. 1995; 333:1301-7. Google Scholar Author, Article, and Disclosure InformationAuthors: Joseph S. Alpert, MD; Howard R. Horn, MDAffiliations: 1997-98 Series.John Roberts, MD, Editor.From the University of Arizona Health Sciences Center, Tucson, Arizona, and the University of Tennessee, Memphis, Tennessee.Corresponding Author: Joseph S. Alpert, MD, Department of Medicine, University of Arizona Health Sciences Center, 1501 North Campbell Boulevard, Room 6334, Tucson, AZ 85724.Current Author Addresses: Dr. Alpert: Department of Medicine, University of Arizona Health Sciences Center, 1501 North Campbell Boulevard, Room 6334, Tucson, AZ 85724. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byCONGESTIVE HEART FAILURE IN OLDER ADULTS 1 September 1997Volume 127, Issue 5Page: 388-394KeywordsAngioplastyCholesterolClinical trialsDrugsExerciseHeart failureMortalityMyocardial infarctionStable coronary artery diseaseVitamin E ePublished: 15 August 2000 Issue Published: 1 September 1997 Copyright & PermissionsCopyright © 1997 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...