tbuckley/cabot-search huggingface dataset:
Diagnosis of Tuberculosis by Nucleic Acid Amplification Methods Applied to Clinical Specimens
Journal: JAMA (1993)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Gangrene in Hemoglobin C-Trait After Exposure to Cold
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
压力与皮肤病生活质量:焦虑敏感性社会关注的缓和作用
Authors: L.J. Dixon, S.M. Witcraft, N.K. McCowan, R.T. Brodell
Journal: British Journal of Dermatology (2018)

Summary “压力”一词用于形容一个人感到紧张或在压力下的状态。一个有趣的事实是,压力可以使某些皮肤病恶化,甚至引起一些皮肤病。这会导致患者产生恶性循环,他们的皮肤病会引发更多压力,压力会转而恶化其症状,如此循环。关于在压力和皮肤病之间的关联中起作用的心理风险因素却鲜为人知,但业界普遍认为其中一个相关因素是“焦虑敏感性(AS)社会关注”。这会在一个人因担心社会后果(其他人的反应,例如拒绝或羞耻)而惧怕焦虑相关的感觉(例如出汗、脸红)时发生。因此,这个人是在担心焦虑症的可视迹象。在这项于美国开展的研究中,237名带有皮肤病症状的患者完成了一些调查问卷,用以评估压力、AS社会关注、皮肤病生活质量和皮肤症状的严重程度。研究发现,具有AS社会关注症状的患者更有可能注意和惧怕因压力或皮肤病引起的体征所产生的社会反响(例如其他人会如何反应),进而恶化皮肤病对其情绪健康和日常生活的影响。但是,具有高度AS社会关注症状的患者并未反应其皮肤病的体征影响了其生活质量,这表示压力与症状的严重程度并无关联。
Hemolytic anemia in Wilson's disease. A report of three cases with transient increase in hemoglobin A2
Authors: G. A. Robitaille
Journal: JAMA (1977)

Three patients with Wilson's disease and initial manifestations of intravascular hemolysis also had transient elevations of hemoglobin A<sub>2</sub>. It is important to recognize such manifestations in establishing an early diagnosis. (<i>JAMA</i>237:2402-2403, 1977)
Abstract 1612: Pharmacological Postconditioning Effect of G-csf Is Mediated through Activation of Pi3k-akt-enos Pathway and Opening the Mitochondrial Katp Channels in a Rabbit Model of Myocardial Infarction
Authors: Shohei Sumi, Masamitsu Iwasa, Hiroyuki Kobayashi, Shinji Yasuda, Takahiko Yamaki, Bau Narantuoya, Shinya Minatoguchi
Journal: Circulation (2008)

It has been reported that granulocyte-colony-stimulating factor(G-CSF) improves cardiac function after myocardial infarction (MI). However, its direct effect on the myocardium and its signaling pathway remain unclear. We examined the acute beneficial effect of G-CSF on myocardial infarct size and its precise mechanisms in a rabbit model of myocardial infarction. In 80 Japanese white rabbits, MI was induced by 30 min of ischemia and 48 hours of reperfusion. Rabbits were intravenously injected with 10 μg/kg of G-CSF (G-CSF group, n=10) or saline (control group, n=10) immediately after reperfusion. The G-CSF+5HD group (n=10) was injected with 5-HD(5-hydroxydecanoate, a mitochondrial KATP channel blocker) 5 min before G-CSF injection. The G-CSF +wortmaninn group (n=10) was injected wortmaninn (0.6mg/kg) 5 min before G-CSF injection. G-CSF+L-NAME group (n=10) was injected with L-NAME (10mg/kg) 5 min before G-CSF injection. The 5HD alone (n=10), wortmannin alone (n=10), L-NAME alone (n=10) groups were respectively injected 5HD, wortmannin and L-NAME immediately after reperfusion. Myocardial infarct size was calculated as a percentage of the risk area of the left ventricle. Western blot analysis was performed to examine the Akt and phospho-Akt and phospho-eNOS in the ischemic myocardium at 48 hours of reperfusion. The infarct size was significantly smaller in the G-CSF group (26.7±2.7%) than in the control group (42.3±4.6%). The infarct size-reducing effect of G-CSF was completely blocked by 5-HD (42.5±1.66%), wortmaninn(44.7±4.81) and L-NAME (42.1±4.2%). Wortmannin, L-NAME or 5HD alone did not affect the infarct size. Western blotting showed higher expression of phospho-Akt and phosho-eNOS in the infarct area in the G-CSF group than in the control group. G-CSF administered immediately after reperfusion reduces myocardial infarct size via activation of PI3K, Akt, eNOS and opening the mitochondrial KATP channels.
A Handbook of Midwifery.
Journal: JAMA (1897)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Understanding patients' decisions. Cognitive and emotional perspectives
Authors: D. A. Redelmeier
Journal: JAMA (1993)

<h3>Objective.</h3> —To describe ways in which intuitive thought processes and feelings may lead patients to make suboptimal medical decisions. <h3>Design.</h3> —Review of past studies from the psychology literature. <h3>Results.</h3> —Intuitive decision making is often appropriate and results in reasonable choices; in some situations, however, intuitions lead patients to make choices that are not in their best interests. People sometimes treat safety and danger categorically, undervalue the importance of a partial risk reduction, are influenced by the way in which a problem is framed, and inappropriately evaluate an action by its subsequent outcome. These strategies help explain examples where risk perceptions conflict with standard scientific analyses. In the domain of emotions, people tend to consider losses as more significant than the corresponding gains, are imperfect at predicting future preferences, distort their memories of past personal experiences, have difficulty resolving inconsistencies between emotions and rationality, and worry with an intensity disproportionate to the actual danger. In general, such intangible aspects of clinical care have received little attention in the medical literature. <h3>Conclusion.</h3> —We suggest that an awareness of how people reason is an important clinical skill that can be promoted by knowledge of selected past studies in psychology. (<i>JAMA</i>. 1993;270:72-76)
P296 Effect of tiotropium/olodaterol therapy on copd exacerbations in the tonado® studies
Journal: Thorax (2016)

AbstractE Derom, outside of the submitted work, reports financial support from Boehringer Ingelheim, Actelion, AstraZeneca and Cipla for consultancy work, financial support from Chiesi, AstraZeneca and CSL Behring for advisory board attendance, and research support from Boehringer Ingelheim and GlaxoSmithKline.M Fležar has received personal fees from Boehringer Ingelheim and institutional financial support from Novartis.L Grönke and F Voß are employees of Boehringer Ingelheim Pharma GmbH & Co. KG.R Buhl reports financial support to his institution from Boehringer Ingelheim during the conduct of the study and, outside of the submitted work, financial support from Boehringer Ingelheim, AstraZeneca, Chiesi, Novartis, Teva, Roche and GlaxoSmithKline for attendance at advisory boards and speaking activities, and research support to his institution from Boehringer Ingelheim, GlaxoSmithKline, Novartis and Roche.
Careers for Nurses.
Journal: JAMA (1952)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
REDUCTION IN MORTALITY IN DIPHTHERIA IN AUSTRALIA DUE TO USE OF ANTITOXIN.
Journal: JAMA (1900)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
MORTALITY STATISTICS FOR 1916
Journal: JAMA (1918)

The report of the Bureau of the Census on the mortality statistics covering the registration area for 1916 has just appeared. The death rate was 14 per thousand population, slightly exceeding the rates for 1914 and 1915, which were 13.6 and 13.5, respectively, but slightly lower than that for 1913, which was 14.1. Of the 1,001,921 deaths that occurred in the registration area, 54.7 per cent. were males and 45.3 per cent. famales. Infants under one year of age constituted 16.4 per cent. of all deaths, continuing the gradual decrease that has taken place since 1900 in deaths of infants under 1 year. In 1900 this rate was 20.7 per cent, of the total. The deaths of infants under 5 years have gradually decreased from 30.4 per cent, of all deaths in 1900 to 23.4 per cent. in 1916. The highest death rates in 1916
Is the quality cart before the horse?
Authors: D. B. Nash
Journal: JAMA (1992)

Imagine, for a moment, a private corporation that affects the lives of 32.4 million US citizens and one with yearly expenditures in excess of $113 billion. Yet, the corporation spends less than 0.3% of this figure on a program to ensure the quality of the "product" it delivers.<sup>1</sup>Now, senior officers in this fictitious corporation are proposing sweeping changes that will radically alter the methods for improving the quality of its products; but their proposal lacks a detailed business plan, budget, and convincing evidence of success in a test phase. See also p 900. While some observers may object to my private-sector analogy, I believe the article by Jencks and Wilensky (in this issue ofThe Journal<sup>2</sup>) describes just such a scenario for the Medicare program. Because this article proposes a plan based on a fundamental shift in thinking, I will first attempt to summarize its main points,
ERRATUM
Journal: Journal of Clinical Oncology (2008)

contained errors.In the Results section, under Patient Population, the second to last sentence indicated that four patients had hindgut primary and four had unknown primary, whereas it should have read that three had hindgut primary and five had unknown primary, as follows:"Thirty-five patients had foregut primary, 16 had midgut primary, three had hindgut primary, one had renal primary, and five had unknown primary."In the Results section, under PFS and OS, the third to last sentence of the first paragraph should have indicated that the RAD001 dose of 10 mg was associated with superior PFS, as follows:"When tumor type, dose level, prior octreotide use, and disease status at time of study entry were analyzed in a Cox proportional hazard model, RAD001 dose of 10 mg was associated with superior PFS (HR, 0.5; 95% CI, 0.3 to 0.98), and progression at study entry was associated with shorter PFS (HR, 3.3; 95% CI, 1.5 to 7.2)."In the legend for Figure 2, part D, the 12-month PFS rate was given as 40%, whereas it should have been 49%.In Figure 3, part B, the labels for patients in the lowest quartile (Ͻ 109 U/L) and patients in the higher three quartiles (Ն 109 U/L) were inadvertently transposed.
Cultured skin cells, artificial dermis join in race against time to cover burn wound
Authors: T. Randall
Journal: JAMA (1991)

THE KEY to survival for today's burn patients depends on the expedient closure of the wound after excision of the burned tissue. Yet this objective has become more difficult to accomplish now that many patients with burns that cover 80% or more of their bodies are surviving. With so much tissue burned, less healthy skin is available for autografts, and donor sites take longer to heal with each successive harvest. "We've pushed back survival as far as we can with infection control, nutrition, techniques of excision, and so on. But unless we close the wound, the patient will still die," says William F. McManus, MD, a US Army colonel, and chief, Clinical Division, US Army Institute for Surgical Research (USAISR), Fort Sam Houston, San Antonio, Tex. Typically, the dead, burned tissue is surgically excised around the fourth day after the injury. Yet the hypermetabolism, immunosuppression, and other physiological changes caused
Clinical pharmacokinetics of high-dose metoclopramide in cancer patients receiving cisplatin therapy.
Authors: J E McDermed, J L Cohen, C Joseph, S B Strum
Journal: Journal of Clinical Oncology (1985)

Using a sensitive and specific high-pressure liquid chromatographic (HPLC) assay, we measured serum levels of metoclopramide in 18 cancer patients receiving high-dose intravenous (IV) therapy to prevent cisplatin-induced emesis. Ten patients were treated with one or more courses with metoclopramide alone (1.0 to 3.0 mg/kg) in an open-label study, and eight patients were treated with a fixed 2.0 mg/kg dose of metoclopramide with or without adjunct dexamethasone (20 mg) using a randomized, crossover design. The pharmacokinetics of metoclopramide were determined, and the relationship between serum levels and clinical response was evaluated. The pharmacokinetic parameters of high-dose metoclopramide were found to be similar to those reported for standard promotility doses, and no dose dependency was demonstrated over the range of doses studied. No clear correlation between serum metoclopramide levels and prevention of cisplatin-induced emesis was observed. The addition of dexamethasone resulted in clinical improvement in two of eight patients, but had no effect on serum metoclopramide levels or kinetic parameters. Results in this study population do not show metoclopramide levels to be related to antiemetic effect following IV cisplatin therapy.
MEDICAL LEGISLATION.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Diabetes Case Management
Authors: Anne Nettles
Journal: Annals of Internal Medicine (1999)

Letters18 May 1999Diabetes Case ManagementAnne Nettles, RN, MSN, CDEAnne Nettles, RN, MSN, CDEDiabetes Educator Associates, Inc.; Wayzata, MN 55391 (Nettles)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-130-10-199905180-00008 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Aubert and colleagues' paper (1) is one more example of the contribution that systematic and consistent diabetes nursing skills could provide to people with diabetes. I find it fascinating, however, that it was not suggested that one way to economize while disseminating the practice would be to decrease physician involvement. An experienced certified diabetes nurse can incorporate national multidisciplinary guidelines into care management while providing expert education and behavioral care. The diabetes nurse refers to physicians or dietitians as needed—a normal consultative practice. Show me evidence to support the common assumption that physicians must be involved every ...Reference1. Aubert RE, Herman WH, Waters J, Moore W, Sutton D, Peterson BL, et al . Nurse case management to improve glycemic control in diabetic patients in a health maintenance organization. A randomized, controlled trial. Ann Intern Med. 1998;129:605-12. LinkGoogle Scholar Author, Article, and Disclosure InformationAuthors: Anne Nettles, RN, MSN, CDEAffiliations: Diabetes Educator Associates, Inc.; Wayzata, MN 55391 (Nettles) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoNurse Case Management To Improve Glycemic Control in Diabetic Patients in a Health Maintenance Organization Ronald E. Aubert , William H. Herman , Janice Waters , William Moore , David Sutton , Bercedis L. Peterson , Cathy M. Bailey , and Jeffrey P. Koplan Diabetes Case Management Mayer B. Davidson Diabetes Case Management Robert F. DeBusk , Nancy Houston Miller , and Jeffrey A. West Diabetes Case Management Ronald E. Aubert , Janice Waters , and William H. Herman Metrics 18 May 1999Volume 130, Issue 10Page: 862KeywordsNursesNursing education ePublished: 15 August 2000 Issue Published: 18 May 1999 Copyright & PermissionsCopyright © 1999 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
8. Obesity Management for the Treatment of Type 2 Diabetes:<i>Standards of Medical Care in Diabetes—2021</i>
Journal: Diabetes Care (2020)

The American Diabetes Association (ADA) "Standards of Medical Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, a multidisciplinary expert committee (https://doi.org/10.2337/dc21-SPPC), are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA's clinical practice recommendations, please refer to the Standards of Care Introduction (https://doi.org/10.2337/dc21-SINT). Readers who wish to comment on the Standards of Care are invited to do so at professional.diabetes.org/SOC.