tbuckley/cabot-search huggingface dataset:
Determinism and humanism in modern medicine
Authors: E. D. Robin
Journal: JAMA (1978)

MODERN western medicine grew from two separate philosophical roots—scientific determinism and humanism. The former, based on the doctrine that every experiment done under the same conditions produces the same results, provides the basis of much of modern medicine. It has led to the use of the laboratory, to clinical investigation, and to the development of diagnostic and therapeutic technology. It also determines the manner in which basic and clinical sciences are currently taught in medical schools. <h3>Roots of Modern Medicine</h3> Scientific determinism is indispensable in approaching patient treatment. However, it has important limitations. Many diseases are not well understood. Moreover, there are biologic variations in patients and technical variations in data collection. The second root of modern western medicine, humanism, is based on the principle that the proper concern of man is man. It is a more ancient basis for the physician's role than scientific determinism. Originating early in the
I am planning to move to Spain in two years' time. Any advice on UK qualified doctors working there as general practitioners or in accident and emergency?
Authors: James Sherifi
Journal: BMJ (2005)

In mammalian cells, signaling pathways triggered by TNF can be switched from NF-κB activation to apoptosis and/or necroptosis. The in vivo mechanisms underlying the mutual regulation of these three signaling pathways are poorly understood. In this article, we report that the embryonic lethality of <i>RelA</i>-deficient mice is partially prevented by the deletion of <i>Rip3</i> or <i>Mlkl,</i> but it is fully rescued by the combined ablation of <i>Fadd</i> and <i>Rip3</i> or <i>Mlkl</i> or by blocking RIP1 kinase activity (RIP1<sup>K45A</sup>). <i>RelA<sup>−/−</sup>Fadd<sup>−/−</sup>Rip3<sup>−/−</sup></i> triple-knockout (TKO) and <i>RelA<sup>−/−</sup>Rip1<sup>K45A/K45A</sup></i> mice displayed bacterial pneumonia leading to death ∼2 wk after birth. Moreover, <i>RelA<sup>−/−</sup>Rip1<sup>K45A/K45A</sup></i> mice, but not TKO mice, developed severe inflammation associated with inflammatory skin lesion. Antibiotic treatment improved bacterial pneumonia, extended the lifespan of TKO and <i>RelA<sup>−/−</sup>Rip1<sup>K45A/K45A</sup></i> mice, and alleviated skin inflammation in <i>RelA<sup>−/−</sup>Rip1<sup>K45A/K45A</sup></i> mice. These results show the mechanisms underlying the in vivo mutual regulation between NF-κB activation and the cell death pathway and provide new insights into this interplay in embryonic development and host immune homeostasis.
Railway Surgery. For Railway Surgeons, etc.
Journal: JAMA (1890)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
British Medical Journal, London
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
SAN FRANCISCO'S PLAGUE.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Transposed Data in Abstract
Authors: Christophe Vinsonneau, Mehran Monchi
Journal: JAMA (2016)

John M. Jakicic, PhD; Kelliann K. Davis, PhD; Renee J. Rogers, PhD; Wendy C. King, PhD; Marsha D. Marcus, PhD; Diane Helsel, PhD, RD; Amy D. Rickman, PhD, RD, LDN; Abdus S. Wahed, PhD; Steven H. Belle, PhD
Medicine at a Glance
Journal: JAMA (1984)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Acrocephalosyndactylism
Authors: Alfred Kahn, John Fulmer
Journal: New England Journal of Medicine (1955)

ACROCEPHALOSYNDACTYLISM is a comparatively rare congenital disease characterized by fusion of the digits and a high, peaked head, the highest point being the bregma. If the apex of the skull is posterior to the bregma the changes are not characteristic of this disease.This syndrome was first recognized by Apert1 although previous cases had been described in the literature. The bony changes of the skull were well described by Crouzon.2 There are two extensive and well written reviews on Apert's syndrome.3 , 4 In 1920 Park and Powers5 studied all the previously published cases and summarized their views on its causation and . . .
Voodoo poisoning in Buffalo, NY
Authors: J. R. Saphir
Journal: JAMA (1967)

Because of a highly suggestive history and characteristic clinical manifestations, poisoning (possibly carbon tetrachloride) was diagnosed in a 24-year-old Voodoo worshipper. The poison was apparently included in a medicinal potion prepared by a Voodoo priestess. The evidence for the above, while circumstantial, appears medically sound. The episode occurred in the urban North among the American Negroes. It is yet another occult way for the unsuspecting—patient and physician—to be led astray.
Training overweight/obese older women at high risk for breast cancer to use web-based weight loss tools: The HELP pilot study.
Authors: L. A. Cadmus Bertram, J. P. Pierce, R. E. Patterson, H. Ojeda-Fournier, B. A. Parker
Journal: Journal of Clinical Oncology (2011)

e11128 Background: Excess weight is one of the few modifiable risk factors for incident breast cancer. Many programs can achieve a 7% weight loss but few can maintain it over time. Training women to use self-help resources over the internet has potential for reducing intervention costs and ensuring program maintenance. Methods: 50 overweight/obese (BMI≥27.5 kg/m2) women at increased risk of breast cancer (Gail score≥1.7) were identified from a mammography registry and enrolled in the HELP pilot study and randomized with 2:1 probability to a 12-week lifestyle intervention or a comparison group. Twelve telephone-based coaching calls trained participants to use a free, publicly available website to set goals and track performance for dietary intake and physical activity. The comparison group received information but no training. At baseline and 12 weeks, participants were weighed, fitted with an accelerometer for physical activity pattern, and completed questionnaires. Results: At baseline, participants were 60.9±0.79 years of age with a BMI of 33.1±0.60 kg/m2; 39% were daily internet users. Thirty-three were randomized to the intervention group with 91% completing follow-up. Fifty-four percent were able to use the website reliably and found it to be helpful, including 44% of previously nondaily internet users. At 12 weeks, intervention group participants who found the website helpful had lost 5.6±0.7 kg, or 6.7% of initial weight, intervention participants who did not find it helpful lost 0.8 ±0.9kg or 1.1% of initial weight and the comparison group gained 1.0±0.94 kg (89% follow-up) The between-group difference weight change was 4.2 kg (p<.0001). 74% of intervention group participants lost weight, compared to only 34% of women assigned to the comparison group. Conclusions: A 12-session telephone coaching program to train women to use publicly available web-based weight loss programs effectively achieved a large short-term weight loss among the majority of participants. Further follow-up is needed to identify how well the initial weight loss is maintained without further intervention assistance.
SOCIALISTIC TENDENCIES IN MEDICINE
Authors: JAMES A. GARDNER
Journal: JAMA (1922)

It is not my object to decry the benefits to humankind and to civic life which have come from some of the progressive movements brought about by sincere effort; but, in recent years, under cover of promoting the welfare of society or some part of it, there have been permitted to be inaugurated many so-called reforms which, in reality, are little more than the outcome of the emotional desires of restless faddists or of the ideas of extreme and radical discontents. The contention is sane that all reforms of whatever nature should be made only after patient and scientific investigation of the causes and the cure of the evil sought to be corrected, and that the desire to bring about such reforms presupposes knowledge obtained by serious investigation and careful research, unhampered by emotion or prejudice. It is not an exaggeration to state that, in many instances, sincere and enthusiastic
ASN News
Journal: Journal of the American Society of Nephrology (2006)

Renal Week 2006 will take place in San Diego, CA, from November 14 to 19, 2006. Don’t forget to register and reserve your housing, if you haven’t done so already. Please visit the ASN website at [www.asn-online.org][1] for registration, housing and program details! ### Renal WeekEnds Goes to
Crescendo angina pectoris in a 28-year-old man. Successful saphenous vein bypass grafting
Authors: L. B. Housman
Journal: JAMA (1975)

AORTOCORONARY saphenous vein bypass grafting can relieve the symptoms of ischemic heart disease, but it has rarely been reported in very young patients.<sup>1</sup>A 28-year-old man with crescendo angina and no coronary artery disease risk factors recently underwent emergency coronary arteriography and double aortocoronary vein bypass grafting at the University of Oregon Medical School. To our knowledge, this is the youngest such patient reported in the literature. The presence of such advanced disease in so young a patient without the usual risk factors posed important therapeutic and prognostic problems. Although the long-term prognosis for this patient was and is uncertain, excellent immediate therapeutic results seemed readily attainable, and we considered the patient's youth to be a strong indication for aggressive surgical treatment.<sup>2</sup> Our criteria for the diagnosis of "unstable" angina have been defined in a recent report<sup>3</sup>and include chest pain at rest that persists more than 24
Glossary of Genomics Terms
Journal: JAMA (2013)

Mingzhao Xing, MD, PhD; Ali S. Alzahrani, MD; Kathryn A. Carson, ScM; David Viola, MD; Rossella Elisei, MD; Bela Bendlova, PhD; Linwah Yip, MD; Caterina Mian, MD; Federica Vianello, MD; R. Michael Tuttle, MD; Eyal Robenshtok, MD; James A. Fagin, MD; Efisio Puxeddu, MD, PhD; Laura Fugazzola, MD; Agnieszka Czarniecka, MD; Barbara Jarzab, MD, PhD; Christine J. O’Neill, MBBS(Hons), MS; Mark S. Sywak, MD; Alfred K. Lam, MD, PhD; Garcilaso Riesco-Eizaguirre, MD, PhD; Pilar Santisteban, PhD; Hirotaka Nakayama, MD; Ralph P. Tufano, MD; Sara I. Pai, M.D, PhD; Martha A. Zeiger, MD; William H. Westra, MD; Douglas P. Clark, MD; Roderick Clifton-Bligh, PhD; David Sidransky, MD; Paul W. Ladenson, MD; Vlasta Sykorova, PhD
Necrotizing balanitis due to herpes simplex type 1
Authors: R. D. Powers
Journal: JAMA (1982)

A previously healthy, 26-year-old heterosexual man experienced necrotic penile ulcerations with fever, rigors, and difficulty voiding. Urethral instrumentation and treatment with antibiotics were associated with progression of the disease. Type 1 herpes simplex virus was isolated from the penile ulcerations and pustular lesions in the groin and antecubital fossae. Recovery was complicated by a urethral stricture requiring surgical treatment. Herpes simplex type 1 must be considered in the differential diagnosis of severe penile ulcerations; isolation of herpesvirus from such lesions may obviate further diagnostic and therapeutic measures that are unnecessary and, in some cases, counterproductive. (<i>JAMA</i>1982;248:215-216)
Adverse drug events in hospitalized patients
Authors: S. G. Schneeweiss
Journal: JAMA (1997)

<h3>To the Editor.</h3> —Dr Bates et al<sup>1</sup>and Dr Classen et al<sup>2</sup>dem onstrated the significant impact of ADEs on length of stay and costs of hospitalizations. However, the reported economic burden of $4685 for preventable ADEs and $2595 for all ADEs in the article by Bates et al,<sup>1</sup>and $2013 for all ADEs in the work by Classen et al,<sup>2</sup>only consider adverse drug events that were acquired in hospitals. To put the consequences of ADEs during hospitalization in relation to all ADEs, it is necessary to quantify the burden of adverse events in ambulatory care as well. We performed a meta-analytic review of 21 original studies published from 1975 through 1996 and identified 13 reports in adults admitted to medical or emergency services because of ADEs in 4 industrialized countries or regions (United States 3, Europe 8, South Africa 1, Taiwan 1). The meta-analysis used the World
GEORGE MILLER STERNBERG (1838-1915) SURGEON-GENERAL, USA
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Gulstonian Lectures on Pulmonary Cavities: Their Origin, Growth, and Repair
Authors: W. Ewart
Journal: BMJ (1882)

people.But we know that these fevers occur irrespective of changes of temperature, though they have much influence in re-exciting it in those who have previously suflered, but not de novo.The remedy for all this is better drainage, whilst no more water should be used than is required for the crops.(To be continued.
Human Structure
Authors: John E. Skandalakis
Journal: JAMA (1989)

Any time I receive a new anatomy book, I act like a high school boy on his first date—a high school boy of my generation. I enjoy seeing, touching, and reading some of the chapters of the book, which I treat with tender loving care. To me, both the author and publisher of an anatomy book today are heroes, and I love heroes. Anatomy, gross human, is not dead. Anatomy is alive and well. Has the pendulum swung again, or have the cell biologists permitted "anatomy" to survive? Perhaps a peaceful coexistence is springing from the dry well of nonecumenical spirit. <i>Human Structure</i>was first published by WB Saunders in 1972. In this new edition, the authors emphasize in the preface that the textbook is brief, and the 57 chapters are short (635 pages). We agree, but we wonder if the shortening of the book is wise. I enjoyed reading
Editorial Board
Authors: Stephen Mcleod, San Francisco, Daniel Albert, George Bartley, Creig Hoyt, Andrew Schachat, Henry Jampel, Bennie Jeng, Susan Vitale, Dale Fajardo, May Piotrowski, Meredith Jones Senior, Greg Pelkofski, Jeanine Beisel, Anita Agarwal, Ike Ahmed, Tin Aung, Singapore Balwantray, C Chauhan, Emily Chew, Michael Chiang, Mary Cotch, Laura Downie
Journal: Ophthalmology (2019)
Campylobacter Thrombophlebitis
Authors: DAVID B. GEFFEN
Journal: Annals of Internal Medicine (1983)

Letters and Corrections1 July 1983Campylobacter ThrombophlebitisDAVID B. GEFFEN, M.D., VEE J. GILL, PH.D., BRUCE A. CHABNER, M.D.DAVID B. GEFFEN, M.D.Search for more papers by this author, VEE J. GILL, PH.D.Search for more papers by this author, BRUCE A. CHABNER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-99-1-126_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: We report case of septic thrombophlebitis in a patient with Hodgkin's disease due to Campylobacter fetus ssp. fetus (intestinalis). Although Blaser and associates (1) have shown that Campylobacter jejuni is an important cause of enteritis, C. fetus ssp. fetus (intestinalis) is more often associated with systemic disease (2). The single previous report of campylobacter sepsis in a patient with Hodgkin's disease did not distinguish between the two Campylobacter species involved in human infection (3).A 43-year-old patient with Hodgkin's disease had a fever and a sore left arm. Ten days previously he had received intravenous vincristine and...References1. BLASERWELLSFELDMANPOLLARDALLEN MJRRJ. Campylobacter enteritis in the United States: a multicenter study. Ann Intern Med. 1983;98:360-5. LinkGoogle Scholar2. RETTIG P. Campylobacter infections in human beings. J Pediatr. 1979;94:855-64. CrossrefMedlineGoogle Scholar3. KRUTCHIKVELASQUEZ AW. Campylobacter fetus infection in a patient with Hodgkin's disease [Letter]. JAMA. 1977;238:1810-1. CrossrefMedlineGoogle Scholar4. GUERRANTLAHITAWINNROBERTS RRWR. Campylobacteriosis in man: pathogenic mechanisms and review of 91 bloodstream infections. Am J Med. 1978;65:584-92. CrossrefMedlineGoogle Scholar5. VESELYMACINTYRERATZAN DDK. Bilateral deep vein thrombophlebitis due to Vibrio fetus. Arch Intern Med. 1975;135:994-5. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: National Cancer Institute and the Clinical Center National Institutes of Health Bethesda, MD 20205 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAn unusual case of Campylobacter jejuni pericarditis in a patient with X-linked agammaglobulinemiaInfective endocarditis caused by Campylobacter fetus after allogeneic tooth transplantation: a case reportCampylobacter enterocolitis: general and surgical aspects. 1 July 1983Volume 99, Issue 1Page: 126-126KeywordsCampylobacterCampylobacter jejuniEnteritisFetusesFeversHodgkin lymphomaInfectious diseasesSepsisSystemic diseases Issue Published: 1 July 1983 PDF downloadLoading ...
Patients in nursing homes. Multidisciplinary characteristics and outcomes
Authors: L. Gurel
Journal: JAMA (1970)

A total of 845 patients from 18 Veterans Administration hospitals were studied by physicians, nurses, and social workers at time of transfer into nursing home care and six months after placement. Findings indicated relatively little opposition to nursing home placement from either patients or their families. Descriptive information supports the view that nursing homes are serving a more heterogeneous and a more seriously ill clientele than in the past. The increased use of nursing homes to relieve the pressure for beds in hospitals for treatment of acute illnesses appears to be accompanied by a corresponding decrease in their use as a "dumping ground" for the indigent and unwanted.