tbuckley/cabot-search huggingface dataset:
A Compendium of Dentistry for the Use of Students and Practitioners.
Journal: JAMA (1888)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Cholesterol Screening of Children
Authors: Andrew M. Tershakovec
Journal: JAMA (1991)

<h3>To the Editor. —</h3> In their article describing tracking of cholesterol levels in school-age children, Lauer and Clarke<sup>1</sup>provided no data describing the dietary intake of their subjects and how changes in dietary intake during the study period may have influenced total blood cholesterol levels over time. The link between diet and coronary artery disease received increasing attention by the mass media during the study period (1971 through 1986), and recommendations to reduce consumption of total fat, saturated fat, and cholesterol were widely disseminated. Indeed, a recent analysis<sup>2</sup>of 171 studies completed in the United States showed a steady decline in total and saturated fat consumption from the middle 1960s to 1984, while polyunsaturated fatty acid intake increased. The subjects followed up in the Lauer and Clarke study were told their blood cholesterol values. That knowledge may have given those with high values an incentive to make dietary
Cortisol secretion in Nelson syndrome: Persistence after "total" adrenalectomy for Cushing syndrome
Authors: P. D. Papapetrou
Journal: JAMA (1975)

In two patients who were severely pigmented (Nelson syndrome) following bilateral adrenalectomy for Cushing syndrome, symptoms of hypercortisolism developed while they were receiving only physiologic steroid replacement. Cortical assays proved that endogenous cortisol production had not been obliterated. Even after total adrenalectomy, steroid measurement should be performed to guard against adrenocortical excess. (<i>JAMA</i>234:847-849, 1975)
Incorrect Wording
Authors: Jeffrey Plagenhoef, Ge Bai
Journal: JAMA (2017)

must be significantly greater so physician businesses can remain open to provide care.The letter stated that no study exists illustrating that Medicare underpays certain medical specialties compared with other specialties and payers; and that no national database exists containing physicians' billing amounts.However, a 2007 US Government Accountability Office (GAO) report demonstrated Medicare paid physician anesthesiologists 33% of average commercial insurance payment rates. 2 Annual American Society of Anesthesiologists surveys have corroborated the GAO report in subsequent years. 2,3In addition, FAIR Health is a respected, independent database of physicians' billed charges that serves some states and commercial insurance companies as the most valid benchmark for payments. 4 The study furthers the inaccurate narrative that patients receive large balanced bills because of physician charges, instead of overly complicated insurance policies with gaps in coverage caused by inadequate minimum benefits standards and networks and huge copays and deductibles.
Error in Figure.
Journal: JAMA (1993)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Genetic evidence that HNF-1α–dependent transcriptional control of HNF-4α is essential for human pancreatic β cell function
Authors: Sara K. Hansen, Marcelina Párrizas, Maria L. Jensen, Stepanka Pruhova, Jakob Ek, Sylvia F. Boj, Anders Johansen, Miguel A. Maestro, Francisca Rivera, Hans Eiberg, Michal Andel, Jan Lebl, Oluf Pedersen, Jorge Ferrer, Torben Hansen
Journal: Journal of Clinical Investigation (2002)

Mutations in the genes encoding hepatocyte nuclear factor 4α (HNF-4α) and HNF-1α impair insulin secretion and cause maturity onset diabetes of the young (MODY). HNF-4α is known to be an essential positive regulator of HNF-1α. More recent data demonstrates that HNF-4α expression is dependent on HNF-1α in mouse pancreatic islets and exocrine cells. This effect is mediated by binding of HNF-1α to a tissue-specific promoter (P2) located 45.6 kb upstream from the previously characterized Hnf4α promoter (P1). Here we report that the expression of HNF-4α in human islets and exocrine cells is primarily mediated by the P2 promoter. Furthermore, we describe a G → A mutation in a conserved nucleotide position of the HNF-1α binding site of the P2 promoter, which cosegregates with MODY. The mutation results in decreased affinity for HNF-1α, and consequently in reduced HNF-1α–dependent activation. These findings provide genetic evidence that HNF-1α serves as an upstream regulator of HNF-4α and interacts directly with the P2 promoter in human pancreatic cells. Furthermore, they indicate that this regulation is essential to maintain normal pancreatic function.
European Perspectives
Journal: Circulation (2006)

may be argued that the application of novel therapies is facilitated by less restricted regulations as compared, for example, to the United States.Yet this does not appear to be the only reason.As discussed by Francisco Fernandez-Aviles, MD, PhD, (see box, above), the different structure of the clinical cardiology departments in Europe, which combine clinical and basic science under one roof, may contribute to an easier transition to the clinical application of the theories.Based on the present achievements, one might wish that European groups would combine their efforts to further strengthen stem cell research, to translate this research into clinical practice, and to learn from the ongoing trials ("reverse-translation") in order to optimise postinfarction heart failure treatment.
Erratum
Authors: Mr Hart, , Wimp', Clifford Allbutt, J Brierley, Old Alm'a'house, W Bruce, M Burilie, T -Brad- Ford;', F Dolan, M Greenwood, Hackney London, ' De, Havilland Hall, Wimpole Street, Lon - 'don, W Mr, L Hunt, F Jaekson, Mr Brindley, Jamaica Road, S Bermondsey, W Ord, Brook ' Upper, Harley Street, Glossop Road, M Sincock, Friarn Street, E '-Noble, F Smith, Anne Street, ' London, W Mr, L Wallace, Foulden Lodge, N Treasurers, G Herman, Portland Place, W London, Mr Bartlett, Con- Iaught Square, Mswimpole Edwards, A Gubb, J Hunt, J Piekett, Colville Square, W Knowsley Sibley, Upper -Brook Street, W Mr, Austin Upton, E Sir, T Wells, F Allan, Slough Charsley, G Crowe, C Firth, W Frazer, Clifton Griffiths, F Mutch, W Newman, W Smith, Brighton-; Stephens
Journal: BMJ (1893)

Aerest for the future at two and a-half per cent.A 'consi- dr,ble part of the reserve-r25,000-was motgaged for 'AhtitUties, a provision put by, riot for contingencies,.15t4o1ieertain and unavoidable claims upon it, and therefore: 'Ut !WiV'npt be ready to undertake to meet those claims.That *ihs 'pah of.the business on which there was the least ',iiargin.Tle Society was granting annuities 'almost up to the, rfull value af the amount paid.The life assurance business was, Amall, wh1ichlas .due to the fact that the sum for which a p6rs'on could insure his life was inadequate.On the other hand, there was a certain advantage for the Society to remain under-.theFrienldly Societies Act, which prohibited an in- surhie'e of 'more.than' £200.Arrangement had been made with-'th1e' Rock Life Assurance Society, who were willing to.
On Disorders of Assimilation, Digestion, Etc.
Journal: JAMA (1902)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Are Tumor Registries a Good Way To Measure the Quality of Breast Cancer Care?
Journal: Annals of Internal Medicine (2000)

Summaries for Patients2 May 2000Are Tumor Registries a Good Way To Measure the Quality of Breast Cancer Care?Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-132-9-200005020-00031 SectionsAboutFull Text ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail What is the problem and what is known about it so far?Hospital tumor registries record information about cases of cancer treated at a particular hospital. This information is useful in doing cancer research and developing policies on cancer care. Some people would also like to use registry information to judge the quality of treatment for cancer. However, little is known about the accuracy and completeness of tumor registries.Why did the researchers do this particular study?The researchers wanted to determine whether the information in tumor registries provides an accurate picture of the cancer treatment.Who was studied?At ... Author, Article, and Disclosure InformationAffiliations: The summary below is from the full report titled “Determining the Quality of Breast Cancer Care: Do Tumor Registries Measure Up?” It is in the 2 May 2000 issue of Annals of Internal Medicine (volume 132, pages 705-710). The authors are N.A. Bickell and M.R. Chassin.Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. The summaries may be reproduced for not-for-profit educational purposes only. Any other uses must be approved by the American College of Physicians-American Society of Internal Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoDetermining the Quality of Breast Cancer Care: Do Tumor Registries Measure Up? Nina A. Bickell and Mark R. Chassin Metrics 2 May 2000Volume 132, Issue 9Page: 705KeywordsBreast cancerCancer treatmentChemotherapyHealth care qualityHormonal therapyOutpatientsPatientsRadiation therapySurgery ePublished: 15 August 2000 Issue Published: 2 May 2000 Copyright & PermissionsCopyright © 2000 by American College of Physicians. All Rights Reserved.Loading ...
THE MAYORALTY CONTEST IN CHICAGO.
Journal: JAMA (1897)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Classified Advertising
Journal: JAMA (1985)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Syphilitic Neuroses
Authors: W. R. Gowers
Journal: BMJ (1879)

DISEASES of the nervous system may be conveniently divided into two classes: I.Those which depend, as far as our means of observation enable us to judge, on a primary alteration in the nerve-cells or fibres, or in the interstitial tissue, which is, in its nutritive changes, associated in a remarkable way with the nutrition of the nerve-elements: 2. Those which are due to a primary alteration in the tissues, which protect, support, or convey blood to and from the nerve-textures-diseases of the bones, membranes, and vessels, with which we must class new growths.Diseases of the latter class have, as their consequence, secondary changes in the nerve-tissues, by which their presence is manifested.
A. Manual of Materia Medica and Pharmacology, Comprising all Organic and Inorganic Drugs which are or have been official in the United States Pharmacopeia, together with Important Allied Species and Useful Synthetics. Especially Designed for Students of Pharmacy and Medicine, as well as for Druggists, Pharmacists and Physicians.
Journal: JAMA (1906)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
AUTONOMOUS THYROID NODULES
Authors: N. DAVID CHARKES
Journal: Annals of Internal Medicine (1968)

Letters and Comments1 August 1968AUTONOMOUS THYROID NODULESN. DAVID CHARKES, M.D.N. DAVID CHARKES, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-69-2-405 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editor:In a recent letter to the Editor of the ANNALS(1), I stated that Silverstein, Burke, and Cogan had misinterpreted their data concerning the effects ofL-triiodothyronine (L-T3) on the 24-hr radioiodine uptake in some of their patients with "hot" thyroid nodules, and I suggested that a fall in the 24-hr epithyroid count probably represents accelerated iodine turnover within an autonomous nodule, that is, a thyrotrophin-like action ofL-T3. My conclusions were based upon a study of the 2- and 24-hr uptake values before and afterL-T3in toxic nodular goiter, which my colleagues and I have...References1. CHARKES ND: Autonomous thyroid nodules (letter). Ann. Intern. Med. 68: 254, 1968. LinkGoogle Scholar2. CHARKESCANTORGOLUBOFF NDREB: A three day, double isotope, L-triiodothyronine suppression test of thyroid autonomy. J. Nucl. Med. 8: 627, 1967. MedlineGoogle Scholar3. A statistical analysis of our data is available upon request. Google Scholar4. ODDIERUNDLETHOMASHALESCATT THFFIDIB: Quantitative observations with the thyroxine suppression test of thyroid function. J. Clin. Endocr. 20: 1146, 1960. CrossrefGoogle Scholar1. BURKESILVERSTEIN GGE: Autonomous thyroid nodules (letter). Ann. Intern. Med. 68: 255, 1968. MedlineGoogle Scholar2. CHARKESCANTORGOLUBOFF NDREB: A three day, double isotope, L-triiodothyronine suppression test of thyroid autonomy. J. Nucl. Med. 8: 621, 1967. Google Scholar3. SILVERSTEINBURKECOGAN GEGSR: The natural history of the autonomous hyperfunctioning thyroid nodule. Ann. Intern. Med. 67: 539, 1967. LinkGoogle Scholar4. BURKE G: The triiodothyronine suppression test. Amer. J. Med. 42: 600, 1967. CrossrefMedlineGoogle Scholar5. We are ready to meet at any time, in any place, with the other side in order to exchange statistical analyses of data and de-escalate the conflict. Google Scholar6. ODDIERUNDLETHOMASHALESCATT THFFIDIB: Quantitative observations with the thyroxine suppression test of thyroid function. J. Clin. Endocr. 20: 1146, 1960. CrossrefGoogle Scholar7. McKENZIE JM: Review: pathogenesis of Graves' disease: role of the long-acting thyroid stimulator. J. Clin. Endocr. 25: 424, 1965. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: N. DAVID CHARKES, M.D.Affiliations: Division of Nuclear Medicine Temple University Hospital Philadelphia, Pa. 19140 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byScintigraphic evaluation of nodular goiter 1 August 1968Volume 69, Issue 2Page: 405-406KeywordsFallsThyroid ePublished: 1 December 2008 Issue Published: 1 August 1968 PDF downloadLoading ...
BOOK REVIEWS
Authors: R. CALLAHAN
Journal: JNCI Journal of the National Cancer Institute (1992)

BOOK REVIEWS Get access Regulatory Mechanisms in Breast Cancer: Advances in Cellular and Moleculer Biology of Breast Cancer Marc E. Lippman , Robert B. Dickson , eds. Dordrecht, The Netherlands : Kluwer Acar . Publ., 1990 . 452 pp., illus.$145 ROBERT CALLAHAN ROBERT CALLAHAN Laboratory of Tumor Immunology and Biology National Cancer Institute National Institutes of HealthBldg. 10, Rm. 5B50 Bethesda, MD 20892 Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 84, Issue 7, April 1992, Pages 531–532, https://doi.org/10.1093/jnci/84.7.531 Published: 01 April 1992
Lead Isotopes as a Supplementary Tool in the Routine Evaluation of Household Lead Hazards
Authors: Roberto H. Gwiazda, Donald R. Smith
Journal: Environmental Health Perspectives (2000)

The advent of magnetic sector inductively coupled plasma-mass spectrometry (ICP-MS) allows rapid, accurate, and precise measurement of lead isotopes in environmental and biological samples at a lower cost than traditional methods. This may increase the feasibility of including lead isotope measurements as a routine tool to identify household sources of lead exposure to children. Here, we present three household case studies to illustrate how lead hazard evaluations by an environmental specialist could be supplemented with routine lead isotope analyses of potential lead sources and blood. Sampling for lead isotopes was undertaken following the U.S. Department of Housing and Urban Development regulatory guidelines for the evaluation of lead hazards in housing, and with the consideration of minimizing the additional costs associated with lead isotope measurements. The range of isotopic ratios within a single residence was large enough to allow the characterization of different lead sources, particularly when both major (e.g., (207)Pb/(206)Pb) and minor (e.g., (206)Pb/(204)Pb) isotope ratios were considered. These cases illustrate the utility of the lead isotope method to identify main source(s) of lead exposure to the child; discard unlikely sources of exposure to the child; point to sources of lead to dust; and substantiate or refine the environmental assessment based exclusively on lead concentrations and loadings. Thus, a more effective evaluation of household lead hazards would likely benefit from considering a) lead concentrations and loadings in and around the household environment; b) all isotopic ratios of potential lead sources within that environment; and c) information about behavioral habits, as well as an evaluation of viable pathways of exposure to the child.