tbuckley/cabot-search huggingface dataset:
Response
Authors: Peter K. LaGoy
Journal: Environmental Health Perspectives (1994)

ResponseJames O'Brien of the Illinois EPA correctly points out an error in Table 1 of our arti- cle, namely, that the Illinois 1991 Leaking Underground Storage Tank Manual lists different allowable detection limits (ADLs) for each individual PAH.The ADLs used by Illinois range from 0.0087 mg/kg for benzo[a]anthracene (the source of the value of 0.009 mg/kg used in our table) to 0.100 mg/kg for chrysene.O'Brien also notes that Illinois published an updated version of this manual which lists the same ADLs but presents soil cleanup objectives for individual PAHs rather than the single value of 0.004 mg/kg for total carcinogenic PAHs listed in the 1991 document.The cleanup objectives are of two types, type A for soils that pose a threat to groundwater and type B for soils with a low potential for causing groundwater contamination.The type A objectives range from 0.0026 mg/kg for benzo[a]anthracene to 0.03 mg/kg for chrysene, and the type B objec- tives range from 0.013 for benzo[a]anthracene to 0.15 mg/kg for chrysene.O'Brien also noted that a regulatory proceeding current- ly before the Illinois Pollution Control Board may affect the 1993 soil objectives.We appreciate O'Brien's correction and clarification to our article.
Avascular Necrosis of Bone Following Systemic Steroid Therapy
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A role for CD44 in an antigen-induced murine model of pulmonary eosinophilia
Authors: Shigeki Katoh, Nobuhiro Matsumoto, Kumiko Kawakita, Akira Tominaga, Paul W. Kincade, Shigeru Matsukura
Journal: Journal of Clinical Investigation (2003)

Previous studies established that IL-5–producing CD4+ T cells play a pivotal role in allergic respiratory inflammation. It was also reported that CD4+ T cells express higher levels of CD44 in the airway than in peripheral blood of patients with allergic respiratory diseases. We have used experimental pulmonary eosinophilia induced in mice by Ascaris suum (Asc) extract to investigate the role of CD44 in the development of allergic respiratory inflammation. Intraperitoneal administration of anti-CD44 mAb prevented both lymphocyte and eosinophil accumulation in the lung. Anti-CD44 mAb also blocked antigen-induced elevation of Th2 cytokines as well as chemokines (CCL11, CCL17) in bronchoalveolar lavage fluid (BALF). Treatment with anti-CD44 mAb inhibited the increased levels of hyaluronic acid (HA) and leukotriene concentrations in BALF that typically result from antigen challenge. Anti-CD44 mAb also blocked antigen-induced airway hyperresponsiveness. An anti-CD44 mAb (IM7) inhibited the HA-binding ability of splenocytes associated with decreased levels of CD44. Soluble CD44 levels in serum were increased in Asc-challenged IM7–treated mice, but not in KM201-treated mice, compared with Asc-challenged rat IgG–treated mice. Ab’s that block CD44-HA binding reduced allergic respiratory inflammation by preventing lymphocyte and eosinophil accumulation in the lung. Thus, CD44 may be critical for development of allergic respiratory inflammation.
Suction-assisted lipectomy attracting interest
Authors: M. L. Fuerst
Journal: JAMA (1983)

Responding to patients' requests for "that new fat surgery," 400 plastic surgeons recently learned how to do suction-assisted lipectomy via a live surgery broadcast from UCLA Medical Center. After watching the world's masters describe the technique and its problems, most of the surgeons said they would try it on selected patients. The procedure, which is designed to minimize lumps and bumps—not to serve as a panacea for obesity—involves suctioning out small amounts of fat from certain areas of the body. Since a 14-member panel of the American Society of Plastic and Reconstructive Surgeons (ASPRS) returned from Europe last December with glowing, though guarded, praise for suction lipectomy, plastic surgeons have been flocking by the hundreds to two- or three-day "how-to" continuing medical education (CME) courses. Although nothing beats hands-on experience, those who watched the video from Los Angeles's Century Plaza Hotel agree that a large symposium may be the only
Medical Terminology
Authors: Andrew Kapos
Journal: JAMA (1971)

<h3>To the Editor.—</h3> A medical services are becoming ever more complex, agreed terminology for the allied health vocations which is easy to pro`nounce, spell, and comprehend is badly needed and hard to come by. The article by Silver (<b>217</b>:1368, 1971) proposed a generic term for the "paramedical" vocations. However, the term suggested, "Syniatrist," is, I believe, an unfortunate choice as in conversation it may be confused with "Physiatrist" or "Psychiatrist." The full titles of paramedical roles in the same paper are rather cumbersome ("general practice syniatrist associate," "general practice syniatrist aide"). In the same issue, Smith et al (<b>217</b>:1362) derive a lucid categorization of occupational roles for the health team of the future from their own MEDEX training experience. I am afraid, however, that the new occupational titles suggested by them are not likely to catch on with the millions not versed in medical history. Who would dare
House Calls
Authors: Sidney E. Chapin
Journal: JAMA (1992)

<h3>To the Editor.</h3> —As medical director of the Visiting Nurse Association of Southeast Michigan, I read Dr Galloway's "House Calls"<sup>1</sup>with great interest. In 1923, at the age of 16, I accompanied a physician on his home calls in rural Vermont. As a third-year medical student, aged 25,I was involved in home care with the New York City Visiting Nurse Association—this was part of our medical education at that time. During my internship and residency in various hospitals, there always seemed to be house calls to be answered. This was also true during my preceptorship under Dr Virgil Simpson, a contributor to<i>JAMA</i>in the 1930s. After World War II, I moved to the Detroit area to set up my practice again. The first thing I did there was to call the Visiting Nurse Association, which was already 50 years old. Now at age 83, I still function as
Anaesthesia, London
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Correction
Journal: BMJ (1960)

MEDICAL JOURNAIthe scalar-lead patterns are doubtful.In many cases of ostium-primum atrial septal defect the V.C.G. is radically, different from that seen with an ostium-secundum defect.In theory, at least, it could distinguish between changes that are due to altered position of the heart from changes due to other causes.These are its chief clinical uses at the moment.
Effect of balloon mitral valvuloplasty on left atrial appendage function and spontaneous echo contrast in patients with severe mitral stenosis: A transesophageal echocardiographic follow-up study Kewal C. Goswami, M. Bhaskararao, Rakesh Yadav, Kewal K. Talwar, Vinay K. Bahl and Subbash C. Manchanda. Cardiothoracic Sciences Center, All India Institute of Medical Sciences, New Delhi, India
Journal: Journal of the American College of Cardiology (2001)
Nursing Education
Authors: James M. Faulkner
Journal: New England Journal of Medicine (1950)

WHEN I was invited to speak on this occasion, I was very happy to accept because, over the years, the Massachusetts Memorial Hospitals School of Nursing and Boston University School of Medicine have grown up side by side, sharing the same clinical facilities at the Massachusetts Memorial Hospitals.In the sixty-five years that this training school has been in existence, there have been more important advances in medical science than in all the previous centuries of recorded history. Up to that time, objectives in health professions were largely limited to making patients comfortable, relieving pain, keeping up nutrition and otherwise . . .
Occupational koilonychia
Authors: Rodney Dawber
Journal: British Journal of Dermatology (1974)

Journal Article Occupational koilonychia Get access Rodney Dawber Rodney Dawber Department of Dermatology, North Staffs Hospital Centre, Stoke‐on‐Trent Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 91, Issue s10, 1 July 1974, Page 11, https://doi.org/10.1111/j.1365-2133.1974.tb12470.x Published: 01 July 1974
Viral Encephalitis
Authors: Richard J. Whitley
Journal: New England Journal of Medicine (1990)

VIRAL infections of the central nervous system (CNS) have attracted the attention of historians and physicians for millennia.1 , 2 With the exception of herpes simplex encephalitis,3 , 4 the specific causes of CNS syndromes of viral origin have been difficult and sometimes impossible to identify. With the advent of antiviral therapy, increased attention has focused on the prompt and specific diagnosis, pathogenesis, and treatment of viral infections of the CNS, especially herpes simplex encephalitis. This review will focus on the pathogenesis of such infections and the diagnostic approach to patients with presumed viral infections of the CNS. Although considerable emphasis will be placed . . .
Psychotherapeutic Encounter
Authors: E. Stengel
Journal: BMJ (1970)

iron, on the stimulation and depression of reticulo-endothelial activity, on the reactions to certain bacterial infections and viruses, on the mechanisms of bacterial destruction by reticulo-endothelial cells, on the beha- viour of macrophages in cultures, and on the reaction of the system to grafts and tumours and in shock.Finally, there is a short chapter on the reticulo-endothelial sys- tem in invertebrates.
New York City Skyline View From Staten Island Ferry
Journal: JAMA Internal Medicine (2018)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Internal Medicine HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Internal Medicine journal
Missing Letter Grouping Title in: May 2, 2012, issue of JAMA
Authors: Scott Denardo, Paul Carpinone, David Vock, Christopher Batich, Carl Pepine, Pepine Denardo
Journal: JAMA (2012)

fragments from other intravascular devices have been described and correlated with subsequent adverse clinical events. 6However, there have been no published reports pertaining to DES.Polymer damage and detached microparticles could theoretically contribute to DES-associated complications, including thrombosis, restenosis, and microvascular and endothelial dysfunction.Confirmation of our results would be useful, and further studies should determine physiological and clinical consequences of polymer damage and microparticle detachment.Additionally, the role of other components of DES (eg, drug and stent superstructure) require investigation.
A molecular analysis of viral persistence in surface antigen-negative chronic hepatitis B
Authors: J Kato, K Hasegawa, N Torii, K Yamauchi, N Hayashi
Journal: Hepatology (1996)

To identify the mechanisms of viral persistence in patients with chronic hepatitis B after the acquisition of anti-hepatitis B surface antigen antibodies (antiHBs), we serially analyzed the nucleotide sequence of the envelope region in a cohort of infected patients. Four patients with histological diagnoses of chronic hepatitis B who had at least 5 years of observance by our hospital staff were studied. All but one showed normalization of serum alanine aminotransferase (ALT) concentration after clearance of the hepatitis B surface of antigen (HBsAg) and the appearance of anti-HBs. Hepatitis B virus (HBV) DNA was still detectable by polymerase chain reaction (PCR) amplification assay in serum specimens from two patients, even in the presence of circulating anti-HBs. The envelope gene was amplified by PCR in serum samples obtained both before and after seroconversion, and direct cycle sequencing of the PCR products was performed. A mutation resulting in a premature stop codon was found in the pre-S1 region of one patient just prior to clearance of HBsAg. Two years later, the stop codon was converted to a leucine codon and three mutations developed in the “a” loop. In the other patient, 16 amino acids had been deleted between amino acids 8 and 23 in the pre-S2 region before clearance of HBsAg. After the appearance of circulating anti-HBs, the pre-S2 gene reverted to the wild type but three additional mutations appeared inside the “a” loop. These results suggest that HBV mutates when HBsAg is cleared, which may contribute to viral persistence due to an evasion of the host immune surveillance.
National utilization of cadaver kidneys for transplantation
Authors: G. Opelz
Journal: JAMA (1974)

Through a national collaborative effort, a transplant communications network has been operational for the past four years. A total of 5,077 prospective transplant recipients from 94 centers has been listed. A total of 455 kidneys has been shared between cities. The rapid increase in the number of prospective cadaver recipients has resulted in an increase in the average waiting time for suitable transplant candidates. Since more than half of the patients currently in the pool are at high risk because they are presensitized, an active national kidney sharing program is essential. (<i>JAMA</i>228:1260-1265, 1974)
Relationship of Variability in Residual Symptoms With Recurrence of Major Depressive Disorder During Maintenance Treatment
Authors: J. F. Karp
Journal: American Journal of Psychiatry (2004)

OBJECTIVE: To investigate how residual symptoms from an index episode of major depressive disorder may be associated with recurrence, the authors conducted a trial involving four maintenance treatment approaches and examined 1) whether the level and variability of residual symptoms differed among the maintenance treatment conditions and 2) whether greater symptom variability is associated with a higher likelihood of recurrence and more rapid recurrence. METHOD: Patients enrolled in a maintenance treatment study (N=114) were randomly assigned to one of four maintenance treatment conditions: imipramine plus interpersonal psychotherapy, imipramine alone, interpersonal psychotherapy alone, or no active treatment. Residual symptoms were characterized both as continuous variables (mean values and coefficients of variation for Hamilton Depression Rating Scale and Global Assessment Scale [GAS] scores) and as a categorical variable, the percentage of maintenance evaluations with a Hamilton depression scale score ≥8 (e.g., with a symptom peak). RESULTS: Analysis of variance revealed no differences among the four treatment conditions in patients’ levels of residual symptoms or symptom variability assessed as a continuous variable, but patients in the combined treatment group had fewer symptom peaks, compared to those in the placebo and interpersonal psychotherapy groups. Cox proportional hazards modeling showed that higher coefficients of variation for both the Hamilton depression scale and the GAS scores and a greater percentage of evaluations with symptom peaks were associated with shorter survival times. CONCLUSIONS: A higher level of symptom variability during maintenance treatment is associated with higher risk for recurrence of depression and may provide a specific target for maintenance treatments.
Echocardiography
Authors: Bernard L. Segal
Journal: JAMA (1966)

An echocardiogram is the graphic registration of ultrasound waves reflected from the heart. The waveform recording from the anterior leaflet of the mitral valve is specific for this structure. The mitral valve echocardiogram in patients with solitary mitral stenosis correlates well with the findings obtained through cardiac catheterization and with observations made during open-heart surgery. The motion of the anterior leaflet expressed as a diastolic slope in millimeters per second has been shown to decrease as the mitral valve area lessens. The echocardiogram, obtained without risk or serious technical difficulty, can be used in determining the severity of mitral stenosis. This bedside procedure may also be used to study the evolution of mitral stenosis from the onset of rheumatic activity and to appraise the motion of the leaflet after mitral valvotomy.
Book Review Acta Medica Scandinavica . Supplementum LXXVIII. Rapports et Comptes Rendus du Dix-Septième Congrès de Médecine des Pays du Nord Tenu à Copenhague du 27 au 29 Juin 1935. A. Norgaard. 941 pp. Copenhague: Imprimerie Royale Bagge.
Journal: New England Journal of Medicine (1937)
Correction: Liver Injury and Rosiglitazone
Journal: Annals of Internal Medicine (2000)

Corrections1 August 2000Correction: Liver Injury and RosiglitazoneFREEAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-133-3-200008010-00023 SectionsAboutVisual AbstractPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Editor's Note: In the 18 January 2000 issue, Al-Salman and colleagues reported liver injury in a patient receiving rosiglitazone (1). This report did not identify zafirlukast (Accolate, AstraZeneca, Wilmington, Delaware), another medication that the patient was taking when he presented with liver failure, as a potential hepatotoxin. A reader has brought to our attention that liver toxicity has been reported in association with zafirlukast. The 1999 Physicians' Desk Reference (PDR) reports asymptomatic elevation in aminotransferase levels among patients taking four times the recommended daily dose of zafirlukast (2). The 1999 PDR also states that “Cases of symptomatic hepatitis and hyperbilirubinemia, without other attributable cause, have occurred in patients who received the recommended daily dose of ACCOLATE (40 mg/day).” However, the 2000 PDR adds that “In rare cases, patients have progressed to hepatic failure” (3). Al-Salman and colleagues' patient had begun receiving zafirlukast in December 1997 and was taking 10 mg of the drug per day when he presented with liver injury in June 1999. Zafirlukast therapy was discontinued upon hospital admission, and the patient had not resumed this therapy as of March 2000.References1. Al-Salman J, Arjomand H, Kemp DG, Mittal M. Hepatocellular injury in a patient receiving rosiglitazone. A case report. Ann Intern Med. 2000;132:121-4. LinkGoogle Scholar2. Physicians' Desk Reference. Montvale, NJ: Medical Economics; 1999:3403. Google Scholar3. Physicians' Desk Reference. Montvale, NJ: Medical Economics; 2000:536. Google Scholar Comments0 CommentsSign In to Submit A Comment Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoHepatocellular Injury in a Patient Receiving Rosiglitazone: A Case Report Jameela Al-Salman , Heider Arjomand , David G. Kemp , and Manoj Mittal Metrics Cited byNonsteroidal Antiinflammatory Drugs and Leukotriene Receptor AntagonistsLeukotriene antagonistsAcute hepatocellular injury associated with zafirlukast 1 August 2000Volume 133, Issue 3Page: 237KeywordsAminotransferasesDrugsHepatitisHepatotoxinsLiverToxicity Issue Published: 1 August 2000 Copyright & PermissionsCopyright © 2000 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...