tbuckley/cabot-search huggingface dataset:
Decreasing cardiovascular disease and increasing cancer among whites in the United States from 1973 through 1987. Good news and bad news
Authors: D. L. Davis
Journal: JAMA (1994)

<h3>Objective.</h3> —Trends in cancer mortality, cardiovascular mortality, and cancer incidence are assessed among US whites to determine whether aging of the population and smoking patterns completely account for increased cancer rates from 1973 through 1987. <h3>Design.</h3> —For mortality, percentage changes in age-specific rates were calculated. For cancer incidence, trends in age-specific rates across time periods and birth cohorts were assessed for several sites. <h3>Main Outcome Measures.</h3> —National US cardiovascular and cancer mortality rates and incidence rates for smoking-related cancer, breast cancer, and all other types of cancer in 10% of the US population covered by the National Cancer Institute's Surveillance, Epidemiology, and End Results Program were analyzed. <h3>Results.</h3> —From 1973 through 1987, cardiovascular mortality decreased 42% in the age group 0 to 54 years and decreased 33% in the age group 55 to 84 years; concurrently, cancer mortality decreased 17% in the younger group but increased 12% in the older group. By 1987, even though proportionally fewer people in the older age groups died, relatively more of them died of cancer. Men born in the 1940s had twice as much cancer as those born in 1888 through 1897 and more than twice as much cancer not linked to smoking; women born during this period had 50% and 30% more of these same cancers, respectively. Rates of smoking-related cancers in recent cohorts of women were five to six times greater than in those born in 1888 through 1897, while rates in men declined. Recent cohorts of women also had more than twice as much breast cancer as those born in 1888 through 1897. <h3>Conclusions.</h3> —In recent US birth cohorts, our model found that increases in cancer have occurred that are not solely linked to aging of the population and smoking patterns. In light of these results and similar findings in Sweden, changes in carcinogenic hazards in addition to smoking are likely to have occurred and need to be studied further. (<i>JAMA</i>. 1994;271:431-437)
Oral contraceptives and myocardial infarction: results of the MICA case-control study
Journal: BMJ (1999)

P = 0.04 and raised dust there (15.7, 2.4 to 651; P = 0.01.)Two variables were constructed to refine the logistic regression analysis.For forests the variable was defined by those who spent more than 16 hours a month in forests, who went to forests for wood, or who picked up wood or were exposed to dust or earth during a leisure visit.For exposure in buildings where they may have been rodents the variable was defined by those who spent more than 2 hours there and who cleaned, raised dust, or made a vigorous physical effort.In the final model of the conditional logistic regression analysis, cases were more likely to live less than 50 metres from a forest and have seen rodents in or around their home, to have been digging, to have spent long periods in forests and been in contact with wood or disturbed earth or dust (table).Rodent control was more common among controls.Cases were more likely than controls to both live near a forest and see rodents at home (66.1, 5.7 to 768.9).
Committee on Aerospace Medicine
Journal: JAMA (1962)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Kupffer cell depletion shifts the balance of growth-modulatory cytokines to promote hepatocyte proliferation Dept. of Medicine, Johns Hopkins University, Baltimore, MD
Journal: Hepatology (1995)

Proliferating lipocytes (fat-storing cells or perisinusoidal stellate cells of the liver) were detected by in vivo incorporation of bromodeoxyuridine (BrdU) in an experimental model of cirrhosis in the rat by dimethylnitrosamine. Lipocytes were identified by sequential double immunohistochemical staining on frozen sections using anti-desmin antibodies as a marker of cytoplasmic intermediate filaments followed by anti-BrdU antibodies to identify S-phase nuclei in animals treated for 7, 14 or 21 days. The number of desmin-positive (lipocytes) and desmin-negative (Kupffer and endothelial cells) sinusoidal cells incorporating BrdU was recorded. The labelling index of lipocytes was calculated as the percentage of BrdU-labelled desmin-positive cells with respect to total number of lipocytes. In control animals, when the total number of lipocytes was 153.9 ± 11/mm2 (mean ± 1 S.E.) the number of desmin-posilive S-phase sinusoidal cells never exceeded 6.8 ± 1.2/mm2 with a maximum labelling index of 4.3 ± 0.5%. At 7 days of treatment, the values were respectively 236 ± 26.5/mm2, 53.2 ± 5.9/mm2 and 22.6 ± 0.5% (p < 0.001 vs. controls), while, at 21 days they were 272.5 ± 21.2/mm2, 23.3 ± 4.0/mm2 and 8.5 ± 1.1% respectively (p < 0.01). These results show that hyperplasia of lipocytes represents an early reaction to dimethylnitrosamine-induced liver injury. The local accumulation of lipocytes appear to occur in areas where fibrous septa develop later on.
Spooner Syndrome
Authors: Samuel Vaisrub
Journal: JAMA (1977)

'Tis no secret that physicians can be killjoys. Most of the things that are fun in life turn out to be bad for your health. Witness the exhortations not to smoke vile cigarettes, not to eat rich foods, and not to drink heady wines. Less well known is the joy-jading effect of medical diagnosis on our cherished beliefs. One such belief is that spoonerisms—the seemingly accidental, funny interchanges of first syllables or sounds of words—are anything but deliberate comic inventions. William Archibald Spooner (1844 to 1930), dean of New College, Oxford, was credited with originating spoonerisms when he preached on "Kinquering Congs." Few at the time would have suspected the respected dean of suffering from a cerebral disorder, certainly none of his contemporary Oxford wits who imitated him. And one can be sure that no such thought entered the mind of the vaudevillian who confessed to being "under the affluence
INFANTILE SCORBUTUS.
Authors: ALBERT H. BURR
Journal: JAMA (1896)

Dr. William P. Northrup, editor of the chapter on Scorbutus in the "American Text-book of the Diseases of Children" (1895), says: "The reader will find in this book for the first time scurvy put down as a disease occurring in the United States." It is barely two years since he tabulated some twenty-six American cases, and directed attention to a disease of infancy hitherto overlooked in this country because of its rarity or because of failure in differentiating it from the somewhat kindred disease of rickets; since that time the interest awakened by the discussion of Northrup's papers has brought out reports of a number of cases from observers in different parts of the country. From this it would seem that the disease is assuming greater importance by reason of its increasing frequency in these days of degenerate mammæ, supplemented by the growing indisposition of American mothers to suckle their
Attenuation of cardiac ?-adrenergic receptor signal transduction in cirrhotic cardiomyopathy . Liver Unit, Univ. Calgary, Calgary, Canada and *Dept. Pharmacology, Sapporo Medical University, Sapporo, Japan
Journal: Hepatology (1995)

Previous studies have shown that exercise acutely reduces desire to smoke and withdrawal symptoms among adult smokers; however, no study has examined these effects in younger smokers. This study investigated the impact of a short bout of moderate intensity exercise on desire to smoke, withdrawal symptoms and exercise-induced affect in temporarily abstinent adolescent smokers.Thirty-seven low-active male and female smokers aged 16–19 years, abstained from smoking overnight and were assigned to either (i) 10 min of moderate intensity cycle ergometry (n = 18) or (ii) a placebo control condition that involved very light intensity cycle ergometry (n = 19). Measures of desire to smoke, the Mood and Physical Symptoms Scale (MPSS) and Subjective Exercise Experience Scale (SEES) were administered at baseline, 5 min during, 5 min after and 30 min after both conditions.A significant interaction effect for group by time was recorded for psychological distress scores, when the baseline value was covaried. Follow-up tests indicated that the exercise group reported significantly higher PD scores than the placebo control during exercise, but not at any other time point. No other significant effects were found for any other variables. Unlike research involving adult populations, a short bout of moderate intensity exercise did not alter desire to smoke among abstaining adolescent smokers and may negatively impact affective responses during exercise.
COUNTRY PRACTICE.
Journal: JAMA (2006)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Effect of Human Growth Hormone on Metabolic Response to Surgical Trauma
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Blood Volume Measurements With a New Instrument
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
CORRIGENDA.
Journal: JAMA (1889)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A CASE OF AUTO-CESAREAN SECTION.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Correction: Novel Hybrid Phenotype Revealed in Small Cell Lung Cancer by a Transcription Factor Network Model That Can Explain Tumor Heterogeneity
Authors: Akshata R. Udyavar, David J. Wooten, Megan Hoeksema, Mukesh Bansal, Andrea Califano, Lourdes Estrada, Santiago Schnell, Jonathan M. Irish, Pierre P. Massion, Vito Quaranta
Journal: Cancer Research (2019)

In the original version of this article (1), Fig. 1 was incorrectly replaced with Fig. 2. The error has been corrected in the latest online HTML and PDF versions of the article. The publisher regrets this error.
Evaluating the utility of the QUAL-EC in the clinical care of patients with advanced cancer.
Authors: Anne Wilkinson, Susan Slatyer, Anna K. Nowak, Cathy Pienaar, Anil Tandon, Mark Wallace
Journal: Journal of Clinical Oncology (2016)

e18204 Background: Improvement of quality of life (QoL) is a fundamental goal of care for people with advanced cancer. The Quality of Life at the End of Life (QUAL-E) instrument was developed to measure four domains: Symptom control; Relationship with healthcare provider; Preparation for end of life (concerns about loved ones); and Life completion. Piloting the QUAL-E with Australian palliative inpatients (n = 52) demonstrated acceptability and face validity. A reduced 17-item instrument, the QUAL-E-Cancer (QUAL-EC), validated with Canadian patients (n = 464) was recommended to assess QoL in people with advanced cancer. This study evaluated the utility and feasibility of the QUAL-EC by: • Exploring associations between QUAL-EC domain scores and distress. • Exploring in-depth responses to the QUAL-EC when administered as an interview. Methods: A cross-sectional, mixed methods design was used. Convenience sampling recruited patients with advanced cancer and a prognosis of less than 12 months from a tertiary hospital. Participants completed the QUAL-EC and the Distress Thermometer Screening Tool4 (DT). Qualitative data collection involved digital recordings of QUAL-EC interviews. Results: The accrual target of 25 inpatients (78% response) and 25 outpatients (96% response) was reached. The mean age was 59.9 years. The most common diagnoses were mesothelioma (26%), and cancers of the lung (22%) and brain (10%). Patients’ DT scores indicated that 39.6% were experiencing severe distress (score ≥ 7) while 40% reported moderate distress (score 4-6). Levels of distress significantly correlated with two QUAL-EC domains: Symptom control (r= 0.52, p < 0.001) and Preparation for end of Life (r= 0.32, p < 0.05). Qualitative analysis described the influence of pervasive emotional stress, bothersome symptoms, and psychosocial factors on QUAL-EC responses. Conclusions: Distress was associated with either symptom burden, or concerns about loved ones. When distress is identified on screening, the QUAL-EC offers potential as an instrument capable of nuanced assessment to direct intervention towards psychosocial or physical and symptom-related concerns.
BOOK REVIEWS
Authors: J. CURRIE
Journal: JNCI Journal of the National Cancer Institute (1990)

BOOK REVIEWS Get access Practical Gynecologic Oncology . Jonathan S. Berek , Neville F. Hacker , eds. Baltimore : Williams & Wilkins , 1989 , 691 pp. $61.50. JOHN CURRIE JOHN CURRIE 201 Houck, Johns Hopkins Hospital600 N. Wolfe St. Baltimore, MD 21205 Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 82, Issue 7, 4 April 1990, Page 623, https://doi.org/10.1093/jnci/82.7.623 Published: 04 April 1990
Lateral Osteotomy in Rhinoplasty
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Eugene Sue
Authors: George E. Ehrlich
Journal: New England Journal of Medicine (1959)

YOUNG Eugene Sue, later to win renown as a novelist, was given no choice of vocation. He was forced into a medical career by his iron-willed father, Jean Joseph Sue, himself one of an illustrious line of French surgeons and at the time of his son's birth on January 26, 1804, physician-in-chief of the Consular Guard. Proud and respected, he and his second wife, Marie-Sophie Tison Derilly, — an actress, — named their new son Marie Joseph, in honor of the baptismal witness Dame Marie-Josephe Tascher la Pagerie. The latter was the wife of Citizen Napoleon Bonaparte, first consul of . . .
Lehrbuch der operativen Geburtshilfe für Aerzte und Studierende.
Journal: JAMA (1928)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal