tbuckley/cabot-search huggingface dataset:
Recurrent epistaxis secondary to aneurysm of internal carotid artery
Authors: A. L. Poffenbarger
Journal: JAMA (1971)

<h3>To the Editor.—</h3> Epistaxis secondary to the rupture of an aneurysm of the internal carotid artery in its cavernous portion that has eroded into the sphenoid sinus has been reported infrequently. In 1907, Beadles<sup>1</sup>in a report of 555 cases of intracranial aneurysms referred to the case of Nettleship. The patient, a 61-year-old woman, eventually died after 2 1/2 years of recurrent bouts of epistaxis. Associated neurological findings included pain in the nose, and proptosis of the left eye. Similar cases have been reported over the years and an association of such aneurysm with a history of preceding trauma has been stressed by Voris and Basile,<sup>2</sup>Garcia Bengochea et al,<sup>3</sup>Fabian,<sup>4</sup>Kinley and Leighninger,<sup>5</sup>and Seftel et al.<sup>6</sup> In the most recent case reported, repeated bouts of epistaxis from an aneurysm of the cavernous sinus portion of the carotid artery followed a severe head
LP25 : Add-on peginterferon ALFA-2A significantly reduces hbsag levels in hbeag-negative, genotype d chronic hepatitis b patients fully suppressed on nucleot(s)ide analogue treatment: The hermes study
Authors: P. Lampertico, M.R. Brunetto, A. Craxì, G.B. Gaeta, M. Rizzetto, G. Palmieri, M. Colombo
Journal: Journal of Hepatology (2015)
Abdominal Surgery.
Journal: JAMA (1898)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Circulation Research, New York
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract LB-320: Systemic tumor-stroma interactions are prognostic indicators of breast tumor invasiveness
Authors: Russell Bainer, Casey Frankenberger, Daniel Rabe, Sadiq Saleh, Morag Park, Kiran Chada, Yoav Gilad, Marsha Rosner
Journal: Cancer Research (2014)

Abstract Tumor invasiveness dysregulates homeostatic processes within tissues, driving both tumor and stroma cells to locally proliferate while also disrupting tissue boundaries and recruiting cells from distal sites to promote metastatic dissemination. Here, we use an RNA sequencing approach in mouse models of invasive and noninvasive breast cancer to directly test whether the transcriptional changes that occur as invasive tumors disrupt their microenvironment can be used to predict tumor subtype and patient outcomes. We find that tumor and stroma gene expression levels are largely synchronized within the tumor microenvironment, but that the expression levels of a subset of genes with high prognostic potential are strongly negatively correlated and may reflect opposing responses of tumor and normal stroma cells to tissue disruption. We clinically validate these observations in multiple human breast tumor gene expression datasets and demonstrate that stromal transcript levels enable superior classification of breast cancer subtypes relative to those expression changes observed between invasive and noninvasive tumor tissue. We show that local stromal remodelling is partially driven by differential recruitment of macrophages to invasive tumor sites by CCL5, and that invasion-specific gene expression changes that are prognostic for metastasis-free survival in human patients are detectable in stromal tissues far from the primary lesion. Our data indicate that dysregulation of tissue homeostasis by invasive tumors generates transcriptional changes both within the tumor microenvironment and in peripheral tissues that have significant diagnostic and prognostic potential and could facilitate novel patient therapeutic strategies. Citation Format: Russell Bainer, Casey Frankenberger, Daniel Rabe, Sadiq Saleh, Morag Park, Kiran Chada, Yoav Gilad, Marsha Rosner. Systemic tumor-stroma interactions are prognostic indicators of breast tumor invasiveness. [abstract]. In: Proceedings of the 105th Annual Meeting of the American Association for Cancer Research; 2014 Apr 5-9; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2014;74(19 Suppl):Abstract nr LB-320. doi:10.1158/1538-7445.AM2014-LB-320
Book Review Manual of Physical Diagnosis, with Special Consideration of the Heart and Lungs . By Maurice Lewison, M.D., and Ellis B. Freilich, M.D. In collaboration with George C. Coe, M.D. 8°, cloth, 317 pp., with 75 illustrations. Chicago: The Year Book Publishers, Incorporated, 1941. $3.00.
Journal: New England Journal of Medicine (1941)
HIGHER PRELIMINARY REQUIREMENTS
Journal: JAMA (2012)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
AN OPERATION FOR PYOSALPINX WITHOUT LIGATURE, CLAMP, ARTERY FORCEPS OR BLEEDING, BY OVERTHROW PROVISIONAL SUTURE METHOD.REPORT OF FIFTY-NINE CASES WITH ONE DEATH.
Authors: W. D. KELLY
Journal: JAMA (1906)

Pyosalpinx, or pus in the tube, is the result of an inflammatory action in and about the tube, due to an infection. <h3>ETIOLOGY.</h3> The most frequent causes of pyosalpinx are: Abortion or miscarriage, gonorrheal infection, tubercular infection, infection with the<i>Bacillus coli communis, streptococcus or staphylococcus</i>or infection through trauma or extension to tube of an appendicitis. <h3>PATHOLOGY.</h3> If the tube is infected from its proximal end, the mucous membrane is congested and distended with blood, thereby encroaching on the lumen of the tube. The infection is then advanced by this condition of affairs to the ampulla and then to the distal end of tube. Each and every extension causes or will cause what is spoken of by the patient as "cramp" or shooting or boring pains in the ovary. This condition is frequently spoken of by the physician as an "ovaritis," and if the patient becomes remonstrative her case
Amer J of Roentgenology Ill
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Editorial Board
Authors: Sian Lewis, Patrick Wilken, Katja Brose, Lewis Packwood, Lara Crow, Mat Mccutcheon, Philip Patenall, Neill Sharp, Anders Björklund, Sweden Lund, Sarah Paul Bolam, Barry Dickson, John Disterhoft, Chris Doe, John Flanagan, Craig Garner, Yukiko Goda, Meyer London, Robert Malenka, Mark Stanford, Richard Mattson, Venkatesh Morris, Maiken Murthy, Nancy Rothwell, Mike Shadlen, Marc Tessier-Lavigne, Chris Walsh, J Lawrence, John Fondon, Elizabeth Hammock, Anthony Hannan, David King, Gary Bargary, Kevin Mitchell, Takumi Takizawa, Eran Meshorer, Anna Catania, R Fields, John Zimmerman, Nirinjini Naidoo, David Raizen, Pierre-Marie Lledo, Florian Merkle, Arturo Alvarez-Buylla, Daniel Senkowski, Till Schneider, John Foxe, Andreas Engel, Gdnf Gfr␣, Gustavo Paratcha, Fernanda Ledda, Ithai Rabinowitch, Idan Segev, Vladimir Parpura, Umar Mohideen
Journal: Trends in Neurosciences (2008)
BK Virus-Specific T Cell Immune Reconstitution after Allogeneic Hematopoietic Stem Cell Transplantation
Authors: Eduardo Espada, Ann E. Woolley, Jason Avigan, Edouard Forcade, Maria V.D. Soares, Sarah Nikiforow, Vincent T. Ho, Corey S. Cutler, John Koreth, Philippe Armand, Edwin P. Alyea, Robert J. Soiffer, Joseph H. Antin, João F. Lacerda, Haesook T. Kim, Francisco M. Marty, Jerome Ritz
Journal: Blood (2016)
Functional status changes following medical or surgical treatment for cerebral ischemia. Results of the extracranial-intracranial bypass study
Authors: R. B. Haynes
Journal: JAMA (1987)

To determine the value of extracranial-intracranial arterial anastomosis (EC/IC bypass), we randomly allocated 1377 patients with symptomatic atherosclerosis of the internal carotid or middle cerebral arteries to medical care alone or to EC/IC bypass with continuing medical care. As previously reported, surgery did not reduce—or significantly increase—the risk of stroke. Functional status data collected during the trial provide new information. Six weeks following entry, surgical patients showed greater dysfunction in the following activities: fluency of speech, getting in and out of bed, sitting down and standing up, toileting, cutting food and pouring beverages, and dressing and undressing. At 4.5 months, surgical patients still exhibited greater dysfunction in toileting, with nonsignificant trends in several other activities. From six months onward, there were no significant differences between the groups. Thus, EC/IC bypass results in transient worsening of functional status beyond the immediate perioperative period. (<i>JAMA</i>1987;257:2043-2046)
The Development of Botulinus Toxin in Frozen Peas
Journal: JAMA (1934)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Deaths Among Drivers of Off-Road Vehicles After Collisions With Trail Gates—New Hampshire, 1997-2002
Journal: JAMA (2003)

During April-July 2002, three deaths occurred on New Hampshire trails when adolescents driving off-highway recreational vehicles (OHRVs) collided with trail gates. Because of these three incidents, the New Hampshire Department of Health and Human Services conducted a study to determine the extent of the problem and characteristics of the fatal events. This report describes trail gate fatalities in New Hampshire during 1997-2002. To prevent trail gate collisions, efforts should focus on increased enforcement of OHRV operating rules, driver education, enhanced gate visibility, and improved signage.
PERCUTANEOUS LASER RECANALISATION OF CORONARY ARTERIES
Authors: M. Pashazadeh, P.H. Kidner, G. Davies, D.C. Cumberland, I.R. Starkey, G.D.G. Oakley, J.S. Fleming, G.H. Smith, J.J. Goiti, D.I. Tayler, J. Davis
Journal: The Lancet (1986)
Lung Function
Authors: I. W. B. Grant
Journal: BMJ (1975)

Myasthenia gravis is one of the most satisfying neurological disorders to treat. There are few other conditions in which therapeutic intervention can take a patient from being bed-bound and ventilated to normality. Most patients present with less severe symptoms, but even mild extraocular muscle weakness can be profoundly disabling. The standard therapeutic approach is successful for most patients, which can make the non-specialist neurologist somewhat blasé about its management. However, panic can set in when the standard approach fails. Failure is often the result of incorrect diagnosis, or inappropriate use of first-line treatments. This article outlines the main reasons for failure and gives advice on alternative therapeutic strategies.
THE MECHANISM OF EXOPHTHALMOS
Journal: JAMA (1934)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Diagnosis of Down's syndrome at birth.
Journal: BMJ (1976)

daily, one with a bacteriostatic detergent and the other with a shampoo.They tested the comedogenic effect of soaps and shampoos on rabbits' ears and found that seven out of 21 soaps and 10 out of 18 shampoos had some effect, usually slight.They did not produce acne experimentally in man, and they acknowledge that the rabbit's ear may not reflect accurately what happens in patients, but nevertheless they believe on clinical grounds that acne detergicans exists as a rare phenomenon among obsessional washers.They also suggest that washing may play an important part in aggrava- ting acne vulgaris in the less obsessional.In any case, they argue, washing does little to help acne vulgaris and it is not an important part of treatment-an opinion with which not all dermatologists would agree.Be that as it may, their suggestion needs to be taken seriously, since it is clearly undesirable to recommend any form of treatment in acne vulgaris that can give rise to comedones.We should, perhaps, advise washing in acne vulgaris only in moderation and tell our patients to avoid soaps and other detergents that contain halogenated bacteriostatic agents, especially hexachlorophane, which the authors found to be more comedogenic than the other bac- teriostatics tested.
Amylase Values
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
COMING MEETINGS
Journal: JAMA (1941)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Monatsschrift für Kinderheilkunde, Berlin
Journal: JAMA (1964)

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Recent Advances in Pulmonary Medicine
Authors: Steven E. Weinberger
Journal: New England Journal of Medicine (1993)

The Acquired Immunodeficiency SyndromeThe past decade has seen an explosion of knowledge and literature about one disease, AIDS, that is unprecedented in medical history. Respiratory complications are among the most common clinical problems associated with AIDS; this section will highlight many of the issues concerning these complications, both infectious and noninfectious125,126.Opportunistic pneumonia due to Pneumocystis carinii is the most common respiratory complication in patients with AIDS. The risk of P. carinii pneumonia is greatly increased once the level of CD4+ lymphocytes falls to 200 per cubic millimeter or less127. The clinical picture, characterized by fever, . . .
Randomised controlled trial of treatment for mild hypertension: design and pilot trial. Report of Medical Research Council Working Party on Mild to Moderate Hypertension.
Journal: BMJ (1977)

A multicentre pilot trial to assess the feasibility of undertaking a full-scale national trial of treatment for mild to moderate hypertension has been performed and is being continued. By February 1977 over 1800 patients had entered the trial and some have been under observation for three years. The results so far show that the definitive trial is administratively and scientifically feasible and ethically justified.