tbuckley/cabot-search huggingface dataset:
Optimum Criteria for Diagnosis of Ventricular Septal Defect from Measurements of Blood Oxygen Saturation
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Wernicke's Encephalopathy
Authors: Jeffrey Kramer
Journal: JAMA (1977)

ONE of the most dramatic presentations in clinical medicine is the syndrome of Wernicke's encephalopathy. Although the classic triad of confusion, ophthalmoplegia, and ataxia has been described in nonalcoholic patients with various gastrointestinal disorders and subsequent malnutrition, the recent literature would suggest that these cases are now rare. The diagnosis can be easily overlooked when the patient is in a group not usually suspected to develop the disorder. Such oversight can leave the patient with permanent and devastating neurologic deficits that might otherwise have been avoided by timely specific treatment. In a middle-aged, nonalcoholic woman, Wernicke's encephalopathy followed intravenous hyperalimentation without concomitant vitamin therapy. <h3>Report of a Case</h3> A 63-year-old woman was in good health until June 3, 1976, when she was admitted to another hospital after falling from a ladder. She was noted to be confused on admission and skull and spine roentgenograms disclosed a small basilar skull fracture
Neoplasms after childhood irradiation of the thymus gland
Authors: M. L. Janower
Journal: JAMA (1971)

The oncogenic effects of childhood irradiation of the thymus gland were investigated by following up 466 irradiated subjects, 506 unirradiated subjects with similar illnesses, and the siblings of both series. In the irradiated group there were two malignant and nine benign thyroid neoplasms, indicating an excess risk in this group. There was also a suggestion of an increased risk of breast cancer. There was no evidence of difference between the hospital and sibling controls; this supports the validity of previous studies using sibling controls.
The Tree
Authors: John Savoie
Journal: JAMA (2007)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
FRI0477 Prospective observational study on the evaluation of quality of life in patients affected by enteropathic spondyloarthritis
Authors: MS Chimenti, P Conigliaro, B Polistena, P Triggianese, A Ruffa, C Canofari, F Cedola, S Onali, M Balan, E Calabrese, C Petruzziello, F Spandonaro, G Monteleone, L Biancone, R Perricone
Journal: Annals of the Rheumatic Diseases (2017)

<h3>Background</h3> Enteropathic Spondyloarthritis (ESpA) belongs to the group of Spondyloarthritis (SpA) tipically associated with inflammatory bowel disease (IBD) as Crohn9s Disease (CD) and Ulcerative Colitis (UC). Joint pain is the most common (22–33%) and significant extra-intestinal manifestation in patients with IBD and its management requires reumatological and gastroenterological competence in collaboration. No data concerning the Health-related quality of life (HRQoL) have been evaluated in patients affected by ESpA. <h3>Objectives</h3> Prospective study was performed in a combined GastroIntestinal and RHEumatologic "GI-Rhe" clinic, in order to evaluate: 1) prevalence and characteristics of articular manifestations in a group of IBD patients; 2) quality of life, state of health and well-being in ESpA patients. <h3>Methods</h3> Patients affected by IBD who presented muscolo-skeletal pain between February 2013 and September 2016 (CD 264 and UC 142) were enrolled. New diagnosis, disease management, adverse events as well as laboratory evaluations were assessed every 3 months during the follow-up. Disease activity, function and quality of life in ESpA patients were assessed by ASDAS-CRP, HAQ-S and EuroQol questionnaire. <h3>Results</h3> A total of 427 patients were evaluated for joint involvement (Table 1). The prevalence of SpA in IBD patients was 49.6% (n=212: UC 71 (43.3%), CD 141 (53.4%)), suggesting that the majority of patients with IBD who complain arthralgia may have a concomitant SpA. Other rheumatologic diseases were detected in the study population in 215 patients defined as IBD non-SpA. There was a significantly higher prevalence of active intestinal disease in patients with SpA with respect to IBD-non SpA (CD: CDAI&gt;150 in 18.4% vs 8.2% p=0.004; UC: Mayo score &gt;3 in 15.5% vs 0%, p=0.0004). The evaluation of the EuroQoL demonstrated a mean value of 0.59 in IBD-SpA patients and of 0.55 in IBD non-SpA (Figure 1A). In IBD-SpA, the health related status was: decent 69.8%, good 17.9% and bad 9.4%. In IBD-non SpA, the health related status was: decent in 74.8%, good in 17.7% and bad in 7% of patients. In both groups, none of the patients had a neither exceptional nor great perception of QoL. No significant differences were observed between the two groups (Figure 1B-C). <h3>Conclusions</h3> The joint clinic facilitates diagnosis and management of SpA and IBD. Although IBD-SpA patients showed higher IBD disease activity than IBD-non SpA one, both groups of patients have a good health related QL. <h3>Disclosure of Interest</h3> None declared
Role of nitric oxide and prostacyclin in the control of renal perfusion in experimental cirrhosis*1, *2
Authors: J ROS
Journal: Hepatology (1995)

Nitric oxide (NO) and prostacyclin (PGI2) are two important modulators of renal function under normal conditions; however, little is known on their contributory role in cirrhosis with ascites. In this study, mean arterial pressure, renal hemodynamics, and sodium excretion were measured in 15 rats with cirrhosis and ascites and 16 control rats. Animals were studied in normal conditions, after inhibiting the synthesis of NO (Nω-nitro-l-arginine, 50 μg · kg−1· min−1) or prostaglandins (lysine acetylsalicylate, 15 mg · kg−1 · min−1) and following the concomitant inhibition of both systems. Cirrhotic rats showed increased systemic pressure sensitivity and blunted renal vasoconstrictor response to nitric oxide inhibition as compared with control rats. As a consequence, the glomerular filtration rate increased in cirrhotic rats but not in control rats. In both groups of animals, NO inhibition was associated with significant increased urinary sodium and fractional sodium excretion. The only significant effect observed after prostaglandin biosynthesis inhibition was a decrease in renal plasma flow in cirrhotic rats. The concomitant inhibition of both systems reduced renal plasma flow and did not change glomerular filtration rate, with no differences between control and cirrhotic rats. Prostaglandin inhibition did not prevent the natriuretic effect of the NO inhibitor in both groups of animals. These results indicate that in experimental cirrhosis both NO and PGI2 play an important role in the maintenance of renal perfusion within normal limits.
GRUNDRISS DER KLINISCHEN Therapie INNERER Krankheiten.
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Bacterial translocation-induced inflammation promotes liver fibrogenesis in patients with advanced chronic liver disease
Authors: Benedikt Simbrunner, Philipp Schwabl, Bernhard Scheiner, Rafael Paternostro, David JM Bauer, Alexander Stadlmann, Ernst Eigenbauer, Albert F Stättermayer, Matthias Pinter, Rodrig Marculescu, Michael Trauner, Thomas Reiberger, Mattias Mandorfer
Journal: Journal of Hepatology (2020)
Müller's Serodiagnostic Methods. Authorized Translation
Journal: JAMA (1913)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
British Journal of Radiology, London
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Biosynthesis Of Neuropeptides: Peptide Alpha-Amidation
Authors: B. Eipper
Journal: Annual Review of Neuroscience (1992)

The brain's default mode network consists of discrete, bilateral and symmetrical cortical areas, in the medial and lateral parietal, medial prefrontal, and medial and lateral temporal cortices of the human, nonhuman primate, cat, and rodent brains. Its ...Read More
Combination Chemoimmunotherapy with Pentostatin, Cyclophosphamide and Rituximab Shows Significant Clinical Activity with Low Accompanying Toxicity in Previously Untreated B-Chronic Lymphocytic Leukemia.
Authors: Neil Kay, Susan Geyer, Timothy Call, Tait Shanafelt, Clive Zent, Diane Jelinek, Renee Tschumper, Nancy Bone, Gordon Dewald, Thomas Lin, Nyla Heerema, Laura Smith, Michael Grever, John Byrd
Journal: Blood (2006)
Occupational Dermatoses
Authors: J. G. Downing, S. J. Messina
Journal: New England Journal of Medicine (1946)

INDUSTRIAL medicine made remarkable progress as a result of World War I and World War II. Unprepared in 1917, it rapidly learned by trial and error, so that during the last few years of the later conflict, through preparation and research, it was able to maintain pace with the tremendous production of industry in wartime. Early recognition of the problems of health and hygiene contributed in no small part to the splendid industrial achievement in the United States. Prevention of industrial affections, by the control and elimination of hazards, enabled industry to perform almost a miracle, not only with less . . .
CHILOMASTIX MESNILI ON LETTUCE
Journal: JAMA (1926)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
LONDON
Journal: JAMA (1924)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Antagonist Antibodies to PD-1 and B7-H1 (PD-L1) in the Treatment of Advanced Human Cancer
Authors: Mario Sznol, Lieping Chen
Journal: Clinical Cancer Research (2013)

Abstract The immune suppressive molecule programmed death-1 (PD-1) is upregulated in activated T lymphocytes and inhibits T-cell function upon binding to its ligands B7-H1 (PD-L1, CD274) and B7-DC (PD-L2, CD273). Substantial experimental data from in vitro cell culture systems and animal models, and more recently from clinical trials, indicate that PD-1/PD-1-ligand interactions are a major mechanism of immune suppression within the tumor microenvironment. Initial clinical studies of antibodies directed against PD-1 and B7-H1 showed both an encouraging safety profile and remarkable antitumor activity in subsets of patients with metastatic disease, including malignancies—such as lung cancer—which were previously thought to be unresponsive to immunotherapy. Preliminary data have suggested a correlation between tumor membrane B7-H1 expression and clinical response to anti-PD-1 antibodies. Several key challenges remain to optimize development of PD-1/B7-H1 pathway blockade, including defining the biologic significance of all potential ligand–receptor interactions in the tumor microenvironment, developing more accurate predictive biomarkers of response, determining the breadth of activity in human malignancies, and developing rational combinations of therapy that address key mechanisms involved in positive and negative regulation of antitumor immune responses. Clin Cancer Res; 19(5); 1021–34. ©2013 AACR.
Celiac Plexus Block Relieves Pain
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
What to Do When Faced With Troubling Suspicion That Young Patient May Be Victim of Abuse?
Authors: Suzann Silvermann
Journal: JAMA (1989)

RECORDS KEPT since 1979 indicate that medical personnel have reported approximately 11.2% of child abuse cases each year. That is according to the American Humane Association, Denver, Colo. Physicians in all states are required to notify their state child protection agencies if there is reasonable cause to suspect that abuse has occurred, says Howard Davidson, JD, director of the American Bar Association's National Legal Resource Center for Child Advocacy and Protection, Chicago, Ill. Telephoned reports must be made within 24 hours of the diagnosis, and a written report usually must follow within 36 hours. Some physicians who do not see many child abuse cases may lack confidence in their ability to recognize it, says Robert Reece, MD, director of the family development centers and child protection programs at Boston (Mass) City Hospital and Boston Children's Hospital. However, they are not required to prove anything, says Howard Levy, MD, chief of
Electrocardiography
Journal: JAMA (1934)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Cover
Authors: Suellen Rocca
Journal: JAMA (1985)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal