tbuckley/cabot-search huggingface dataset:
Correction
Journal: BMJ (1946)

diphtheria toxoid.In such individuals any one of the diphtheria antigens-toxoid, A.P.T., or T.A.F.-given in the usual dosage will elicit reactions of varying degrees of severity.Large-scale immuniza- tion of an adult population, or of older school-children, should therefore not be undertaken without preliminary Schick-testing.Pseudo-reactors are preferably not given any injections, as, being already partially immune, they are unlikely to develop diphtheria, and indeed the Schick test material itself is often sufficient to render them negative to further tests.If, however, preliminary Schick-test- ing cannot be done, the safest prophylactic for adults is T.A.F.An initial dose of 0.2 c.cm. should be given to all volunteers, and non- reactors should receive two further doses of 1 c.cm. at three to four week intervals.Reactors should not be given any further injections. Senile PruritusQ.-Is complete rest in bed likely to prove beneficial to an intract- able case of senile prurituis in a patient aged 80 ?A.-Senile pruritus is unlikely to benefit from rest in bed, and might even be made worse, because the patient is able to give more attention to the itching skin.Clicking Joints in a Baby Q.-A mother states that she can hear the joints of the back cracking in her 14-months child.I have been uinable to find any abnormality.Shoiuld I refer the case to an orthopaedic surgeon ?A.-The present writer in an extensive orthopaedic practice has seen a few small infants who have had queer clicking joints.The phenomenon appears to be without any great significance, for these symptoms seem to disappear.Unless there is any clear evidence of physical disturbance one would suggest leaving the problem and reviewing it from time to time.If the mother continues to be dis- tressed by the peculiarities which the child presents it would certainly be worth while seeking confirmatory advice. INCOME TAXAssistant Provided with Furnished House S. B. employs two assistants, each of whom has the use of a free furnished house; he pays income tax on the rental value and also owners' and tenants' rates.*** S. B. can deduct as an expense of the practice
Continuing Increase in Infectious Syphilis— United States
Journal: JAMA (1988)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A Chance of Showers
Journal: JAMA Internal Medicine (2016)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Internal Medicine HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Internal Medicine journal
New partnership pursues research on biosensors
Authors: T. Randall
Journal: JAMA (1993)

THE IMAGE of Dr Leonard "Bones" McCoy on "Star Trek" diagnosing his patient's condition by waving his tricorder inches from the body is still the stuff of science fiction. But what was once only the product of a screenwriter's imagination has become in recent years a field of serious study. At least 50 US companies are now developing biosensors that can measure one or multiple biological substances. These devices include those that analyze a drop of blood, similar to the home blood glucose tests on the market today; others are implanted in the body to provide continuous, real-time portrayals of biochemistry or drug metabolism; and still others, using an infrared light shone through a finger or earlobe, are as noninvasive as the one used by McCoy. Biosensors of the next generation are expected to be smaller, more portable, more rapid in generating a signal, and in many cases less expensive
Development of Viral Diseases and Viral Disease-Like Syndrome After Extracorporeal Circulation
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Volumetric Analysis
Journal: JAMA (1934)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Brucellosis in a group of travelers to Spain
Authors: P. M. Arnow
Journal: JAMA (1984)

An epidemiologic investigation, initiated when<i>Brucella melitensis</i>infection was detected in a high school student, identified five unrecognized cases in classmates. Before the investigation, four infected students had symptoms of brucellosis for one to ten weeks, made nine visits to physicians, and were confined to the school infirmary or hospitals for 27 days. The other two students were asymptomatic when<i>Brucella agglutina-</i>tion testing demonstrated elevated titers, and treatment was quickly instituted when symptoms occurred. Travel to Spain was implicated because cases were clustered in six of 27 travelers compared with none of 23 control students. Food-history questionnaires showed more frequent consumption of cheese by infected than noninfected travelers. This cluster of cases demonstrates the risk of brucellosis in travelers to endemic areas and illustrates the value of an epidemiologic investigation of cases. (<i>JAMA</i>1984;251:505-507)
Section 14.—Serum Sickness and Drug Reactions
Journal: JAMA (1973)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hepatic and portal vein thrombosis in cirrhosis: Possible role in development of parenchymal extinction and portal hypertension*1, *2
Authors: I WANLESS
Journal: Hepatology (1995)

Obliterative lesions in portal veins (PVs) and hepatic veins (HVs) of all sizes are known to occur in cirrhotic livers. PV lesions have generally been attributed to thrombosis, but the pathogenesis of the HV (veno-occlusive) lesions is unknown. We have studied 61 cirrhotic livers removed at transplantation to clarify the prevalence, distribution, and pathogenesis of venous lesions, as well as the association of these lesions with other morphological features and clinical morbidity. Intimal fibrosis that is highly suggestive of healed HV or PV thrombosis was found in at least 70% and 36% of livers, respectively. The distribution of HV lesions was patchy and largely confined to veins between 0.1 and 3 mm in diameter, suggesting multifocal origin in small veins. PV lesions were more uniform throughout the liver, suggesting origin in large veins with propagation to the small veins. HV lesions were associated with regions of confluent fibrosis (focal parenchymal extinction), and PV lesions were associated with regional variation in the size of cirrhotic nodules and a history of bleeding varices. These observations suggest that thrombosis of medium and large PVs and HVs is a frequent occurrence in cirrhosis, and that these events are important in causing progression of cirrhosis.
PUERPERAL ECLAMPSIA.
Authors: W. F. Hertzog
Journal: JAMA (1884)

On page 220, vol. I, of theJournal of the American Medical Association, I reported a case of puerperal convulsions. I now wish to report another case that occurred in my practice since. Mrs. P. H. sent for me in the forenoon of January 7, 1884. I found her suffering from fever, frequent micturition, general anasarca, nausea, violent frontal headache, great restlessness. Diagnosis: uræmia. Gave her three compound cathartic pills as a purge; pot. bitartart. and tinct. digitalis as a diuretic; pot. bromide and chloral hydrate, as a nervous sedative. Early the next morning I was called again, the messenger stating that she was in convulsions. I hurried to the house and found her conscious. Her husband told me that she had had three couvulsions during the night. I now gave her an enema of forty grains of hydrate of chloral, and continued the treatment of the day before. In
Questions and Answers
Journal: JAMA (1973)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Dichotomies in Discovery
Journal: JAMA (1972)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Superitendent of Document Publication Order Form
Journal: JNCI Journal of the National Cancer Institute (1990)

Journal Article Superitendent of Document Publication Order Form Get access JNCI: Journal of the National Cancer Institute, Volume 82, Issue 13, 4 July 1990, Page 1165, https://doi.org/10.1093/jnci/82.13.1165-a Published: 04 July 1990
<i>Helicobacter pylori</i> infection as an independent prognostic factor for locally advanced gastric cancer with curative resection.
Authors: S. Kang, J. Choi, M. Ahn, H. Lee, S. Han, Y. Cho, J. Han, J. Kim
Journal: Journal of Clinical Oncology (2010)

4121 Background: A few studies reported the association between helicobacter pylori (HP) infection and better overall survival (OS) in resected gastric cancer patients (pts). Methods: We investigated the HP infection status and its association with clinicopathologic characteristics in 274 locally advanced gastric cancer pts (stage IB: 25, II: 82, IIIA: 80, IIIB: 39, IV: 48) who underwent adjuvant chemotherapy (CTX) after curative resection (3;D2 dissection). HP infection status in hematoxlin and eosin stained corporal and antral mucosa of non-tumor tissue was graded according to the updated Sydney System and categorized as HP (-) (normal or mild infection) and HP(+) (moderate or marked infection) (Am J Surg Pathol 20:1161, 1996). Eighty-one pts received 5-FU, doxorubicin (DOX) CTX (5-FU 500 mg/m2 weekly for 36 wks, DOX 40 mg/m2 q 3 weeks × 12) with or without OK432, while 193 pts underwent 5-FU, mitomycin-C (MMC), and polysaccharide-K (PSK) CTX (5-FU 500 mg/m2 weekly for 24 wks, MMC 8 mg/m2 q 6 wks × 4, PSK 3 g/day for 16 wks) (Br J Cancer 84:186, 2001, Hepatogastroenterol 54:290, 2007). Results: The median follow-up duration of survivors was 144 (120-184) months. HP (-) was significantly correlated with larger tumor size (> 5 cm) and advanced stage. In univariate analysis, pts with HP(-) (108 pts) demonstrated significantly poor 10-year OS compared with those with HP (+) (166 pts) (21.3% vs. 71.1%, p < 0.0001). HP(-) was associated with poor outcome in all stages except stage IIIB (p = 0.12). In multivariate analysis, HP(-) was the most significant independent prognostic factor of poor OS (hazard ratio: 3.45, 95% CI: 2.43-4.89, p < 0.0001) followed by old age (> 54) (p < 0.0001), advanced stage (p = 0.001), and Bormann type IV (p = 0.027). Conclusions: HP infection status seems to have strong prognostic significance in locally advanced gastric cancer. HP (-) pts may need intensified adjuvant treatment and careful follow-up after curative resection. No significant financial relationships to disclose.
A Public Hospital Closes
Authors: Andrew B. Bindman
Journal: JAMA (1990)

We studied the impact of the closing of a public hospital on patients' access to care and health status. We surveyed individuals who had been medical inaptients at Shasta General Hospital, Redding, Calif, in the year prior to its closing and compared them with those in a second county, San Luis Obispo, whose public hospital did not close. Surveys were administered after the closing of Shasta General Hospital and 1 year later. We assessed outcomes using the Medical Outcomes Study Short Form and a series of transition questions that asked about changes in health over time. Data were available for 88% of patients at 1 year: 219 from Shasta County and 195 from San Luis Obispo County. At follow-up, the percentage of patients from Shasta County who reported no regular provider increased from 14.0 to 27.7 and the percentage who reported they were denied care rose from 10.8 to 16.9. Meanwhile, patients in San Luis Obispo County reported improved access to a regular provider and the level of denied care was unchanged. Patients in Shasta County had significant declines on the Medical Outcomes Study Short Form in health perception, social and role function, and increases in pain as compared with those patients in San Luis Obispo County. The closing of a public hospital had a significant effect on access to health care and was associated with a decline in health status. (<i>JAMA</i>. 1990;264:2899-2904)
Unexplained postoperative fever. Its value as a sign of halothane sensitization
Authors: M. H. Dykes
Journal: JAMA (1971)

This study of consecutive patients reveals that, during the first postoperative week, 55% of temperature elevations above 98.6 F (37 C) are unexplained. Further, only one patient of the 163 who had temperatures recorded for at least three postoperative days failed to demonstrate a temperature elevation. The mean temperatures of four groups of 20 consecutive patients who demonstrated unexplained elevations after four operations fell steadily from between 99.5 F (37.5 C) and 100.4 F (38 C) on the first postoperative day to between 98.6 F and 99.1 F (37.3 C) on the seventh. The maximum elevation was above 99.9 F (37.7 C) in 48 instances. Thirty-two patients who received halothane demonstrated a similar pattern to the 48 who did not. These data do not support the hypothesis that "unexplained postoperative fever" alone, following a prior administration of halothane, necessarily indicates that the patient has become sensitized to the drug.
Pathways to complement activation during cardiopulmonary bypass
Authors: J Ponte
Journal: BMJ (1985)

extra cost of performing tests on an emergency basis.We consider that the incremental cost of such tests should be passed on to the requesting clinician.In this way there would be greater awareness of the additional costs entailed in performing such emergency tests.Clinicians would then be encouraged to judge whether a request could be delayed and incorporated into the routine work of the laboratory concerned.
Quality control
Authors: C A K Bird, C B Brownhill
Journal: BMJ (1978)

<h3>Background</h3> Gastrointestinal duplications are uncommon congenital abnormalities, usually recognised before the age of 2 (80%). Colorectal duplications (CDDs) occur in only 6.8% of cases, rarely in adults, and are revealed by abdominal pain and intestinal obstruction. Malignant changes are uncommon, but are most often found in the colon. <h3>Methods and results</h3> During the last 7 years, the authors have observed seven cases of CDD (three men) with mean age 50.7 years (range 32–73). Four cases were revealed by abdominal pain, and three by intestinal obstruction. Five duplications were located in the caecum, one in the transverse colon, and one in the sigmoid colon. All CDDs were of the cystic type (4.42 cm, range 2–7.5), and three had a communication with the intestinal lumen. All patients except one underwent ‘en bloc’ resection of the cyst with the adjacent colon. On microscopic examination, CDDs contained multiple layers of the bowel wall, including colonic or small intestinal mucosa. Heterotopic gastric mucosa was observed in only one case, high-grade dysplasia in one case, and low-grade dysplasia in another. No invasive carcinoma was found. <h3>Conclusion</h3> Although uncommon, CDDs should be included in the differential diagnosis of all abdominal masses. The treatment approach is excision, in order to avoid any complication. En bloc resection of the colon with CDD may be necessary, because of the intimate attachments of the common wall. Thorough sampling of the specimen is mandatory in order to detect any malignant changes.