tbuckley/cabot-search huggingface dataset:
Abstracts
Journal: Annals of the Rheumatic Diseases (1971)

This paper comes from the Mount Sinai School of Medicine and the New York Medical College, New York.The authors sought evidence of the extent of renal involvement during rheumatic fever by performing percutaneous biopsies in 26 patients who fulfilled the Jones criteria, and the biopsy findings were analysed in relation to various clinical and laboratory features.Biopsies were performed between 10 days and 6 weeks after the onset of rheumatic fever and were examined by liglht and electron microscopy.Antistreptolysin titres were raised in all the 23 sera examined.Biopsy specimens were abnormal in eleven of the sixteen children and six of the ten adults investigated.In fourteen out of fifteen patients with proteinuria greater than 30 mg./100 ml.biopsies were abnormal.Biopsies were also abnormal in three out of six patients with lesser proteinuria and two of five without proteinuria.All patients with macroscopic haematuria or with a blood urea nitrogen greater than 20 mg./100 ml. had abnormal biopsies, as did seventeen of the 22 patients with carditis [criteria unspecified].There seemed to be no significant difference between children and adults.Abnormalities in the biopsies differed in some ways from those of acute glomerulonephritis; the detailed
Interactions between Metals and Microbial Communities in New Bedford Harbor, Massachusetts
Authors: Tim Ford, Jonathan Sorci, Ravi Ika, Jim Shine
Journal: Environmental Health Perspectives (1998)

The fate of toxic metals in marine sediments depends on a combination of the physical, chemical, and biologic conditions encountered in any given environment.These conditions may vary dramatically, both spatially and temporally, in response to factors ranging from seasonal changes and storm events to human activities such as dredging or remediation efforts.This paper describes a program designed to evaluate the interrelationships between the microbial community and pollutants in the New Bedford Harbor, Massachusetts, area, a U.S. Environmental Protection Agency designated Superfund site.Research has focused on establishing distributional relationships between contaminant metals, fluxes of metals between sediments and the overlying water, changes in microbial diversity in response to metals, and potential use of the microbial community as a biomarker of contaminant availability.This research has shown that a significant flux of metals to the water column is mediated by benthic biologic activity, and that microbial communities may be a responsive marker of contaminant stress.A combination of biogeochemical studies and the use of molecular tools can be used to improve our understanding of the fate and effect of heavy metals released to aquatic systems.
Infantile Paralysis: A Symposium Delivered at Vanderbilt University, April 1941
Journal: JAMA (1941)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Treatment Of Sensorineural Hearing Loss By Cochlear Implantation
Authors: J. Nadol
Journal: Annual Review of Medicine (1988)

Cochlear implantation, a form of neural prosthesis, is now being employed for some profoundly deaf individuals. The pathophysiology of profound deafness, the strategies inherent in cochlear implantation, the differences between various cochlear implant strategies and designs, medical and otologic evaluation of implant candidates, and the surgical procedure are each discussed. The results in speech recognition and speech reading that have been obtained with four commonly used cochlear implant systems are also presented.
Commentaire du travail de Yaghoobi M et al., pp. 884
Journal: Endoscopy (2015)

See also: Incidence and predictors of post-ERCP pancreatitis in patients with suspected sphincter of Oddi dysfunction undergoing biliary or dual sphincterotomy: results from the EPISOD prospective multicenter randomized sham-controlled studyEndoscopy 2015; 47(10): 884-890DOI: 10.1055/s-0034-1392418
Simvastatin
Authors: Katarina LeBlanc, Mary T. Brophy
Journal: Annals of Internal Medicine (2003)

Letters17 June 2003SimvastatinKatarina LeBlanc, MD, PhD and Mary T. Brophy, MD, MPHKatarina LeBlanc, MD, PhDBoston Veterans Affairs Healthcare System; Boston, MA 02130 (LeBlanc, Brophy)Search for more papers by this author and Mary T. Brophy, MD, MPHBoston Veterans Affairs Healthcare System; Boston, MA 02130 (LeBlanc, Brophy)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-138-12-200306170-00029-w1 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Simvastatin is an antilipemic agent that decreases low-density lipoprotein cholesterol levels by inhibiting hydroxy-methylglutaryl coenzyme A reductase. Statins have an excellent safety profile (1). However, reports have described a lupus-like hypersensitivity reaction with late, insidious onset (2-4). Symptoms include polymyalgia, elevated erythrocyte sedimentation rate (ESR), positivity for antinuclear antibodies, and potentially life-threatening pneumonitis. To highlight the diversity of this drug-induced hypersensitivity, we report a case in which the patient presented with dysphasia.A 74-year-old man with coronary artery disease and hypertension presented with sudden onset of dysphasia. He was initially thought to have a viral illness, but ...References1. Grundy SM. HMG-CoA reductase inhibitors for treatment of hypercholesterolemia. N Engl J Med. 1988;319:24-33. [PMID: 3288867] CrossrefMedlineGoogle Scholar2. Hill C, Zeitz C, Kirkham B. Dermatomyositis with lung involvement in a patient treated with simvastatin [Letter]. Aust N Z J Med. 1995;25:745-6. [PMID: 8770347] CrossrefMedlineGoogle Scholar3. De Groot RE, Willems LN, Dijkman JH. Interstitial lung disease with pleural effusion caused by simvastin. J Intern Med. 1996;239:361-3. [PMID: 8774391] CrossrefMedlineGoogle Scholar4. Liebhaber MI, Wright RS, Gelberg HJ, Dyer Z, Kupperman JL. Polymyalgia, hypersensitivity pneumonitis and other reactions in patients receiving HMG-CoA reductase inhibitors: a report of ten cases. Chest. 1999;115:886-9. [PMID: 10084510] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Katarina LeBlanc, MD, PhD; Mary T. Brophy, MD, MPHAffiliations: Boston Veterans Affairs Healthcare System; Boston, MA 02130 (LeBlanc, Brophy) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 17 June 2003Volume 138, Issue 12Page: W-53KeywordsAntinuclear antibodiesDrugsEosinophilsErythrocyte sedimentation rateHematocritHypersensitivitySafetySplenomegalyStable coronary artery diseaseStatins ePublished: 17 June 2003 Issue Published: 17 June 2003 Copyright & PermissionsCopyright © 2003 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Cylinder vase
Authors: M. T. Southgate
Journal: JAMA (2003)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Structural and Functional Changes in Acute Liver Injury
Authors: Edward A. Smuckler
Journal: Environmental Health Perspectives (1976)

Carbon tetrachloride produces liver cell injury in a variety of animal species. The first structurally recognizable changes occur in the endoplasmic reticulum, with alteration in ribosome-membrane interactions. Later there is an increase in intracellular fat, and the formation of tangled nets of the ergastoplasm. At no time are there changes in mitochondria or single membrane limited bodies in cells with intact plasmalemma, although a relative increase in cell sap may appear. In dead cells (those with plasmalemma discontinuties) crystalline deposits of calcium phosphatase may be noted. Functional changes are related to the endoplasmic reticulum and the plasma membrane. An early decrease in protein synthesis takes place; an accumulation of neutral lipid is related to this change. Later alterations in the ergastoplasmic functions (e.g., mixed function oxidation) occurs. Carbon tetrachloride is not the active agent; rather, a product of its metabolism, probably the CC1, free radical, is. The mechanisms of injury include macromolecular adduction and peroxide propagation. A third possibility includes a cascade effect with the production of secondary and tertiary products, also toxic in nature, with the ability to produce more widespread damage to intracellular structures.
Real-Time PCR Assays compared to Culture-Based Approaches for Identification of Aerobic Bacteria in Chronic Wounds
Authors: Johan H. Melendez, Yelena M. Frankel, Amanda T. An, Linnea Williams, Lance B. Price, Nae-Yuh Wang, Gerald S. Lazarus, Jonathan M. Zenilman
Journal: Clinical Microbiology and Infection (2009)
THE ROENTGEN RAYS.
Journal: JAMA (1896)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Group Therapy
Authors: Stan Milstone
Journal: JAMA (1976)

<h3>To the Editor.—</h3> I was glad to see Dr Myron F. Weiner's article (234:1181, 1975) on group therapy in "When friends or patients ask about...." Patients do wonder about group therapy, marathons, psychoanalysis, individual psychotherapy, growth groups, etc. There is a plethora of modalities offered, and many people rightly turn to their physician for guidance. Dr Weiner correctly pointed out that the group leader is the most important consideration in making a referral. He then goes on to state The referring physician should seek a sober, thoughtful practitioner rather than a faddish one who has found "Truth" in his method and does not recognize its limitations. Two examples of this kind of naive faddism are Transactional Analysis [TA] and Gestalt Therapy. Unfortunately, Dr Weiner thereby makes the implication that responsible, thoughtful physician-therapists do not practice TA or gestalt therapies. This implication is not true. Qualified transactional analysts (called clinical members)
Highlights
Journal: JAMA Internal Medicine (2018)

In this qualitative study, Krein and colleagues examined types of precaution practice violations and errors in reducing transmission of infectious agents by hospital personnel in clinical units.Trained observers recorded notes while personnel provided care for patients in precautions for a pathogen transmitted through contact or respiratory droplet.Specific occurrences involving potential personnel self-contamination were identified through a directed content analysis.Of 325 room observations, 283 failures were observed, including 102 violations (deviations from safe operating practices or procedures), 144 process or procedural mistakes (failures of intention), and 37 slips (failures of execution), all of which could result in self-contamination.Horwitz provides the Invited Commentary.
OC-001 Inflammatory bowel disease nursing: results of an audit exploring the roles, responsibilities and activity of nurses with specialist/advanced roles within inflammatory bowel disease
Authors: I Mason, K Holbrook, V Garrick, K Johns, M Kane, K Kemp
Journal: Gut (2012)

<h3>Introduction</h3> The role of the nurse specialist in inflammatory bowel disease (IBD) in the UK has developed significantly. Audit work has illustrated the quality indicators provided by the role yet systematic review identified the need for clearer role definition and the completion of a scoping exercise of posts and models of practice. This abstract provides the results of the first UK national audit of IBD nursing. <h3>Methods</h3> Each UK country was represented in the dataset, adults and paediatrics. Inclusion criteria: nurse with a specialist/advanced role caring for patients with IBD. Nurses were identified through the Royal College of Nursing IBD Network and advertising at meetings/nursing press. The audit was in three parts: demographic of the IBD nurse; demographic of IBD nurse service; prospective individual nurse activity over a 10-day period. An electronic reporting system was used to enter data and completed during a 10-day survey period May 2011. <h3>Results</h3> Response rate was 82.5% (198/240). Numbers of IBD nurses are increasing but fall short of the recommended level set by the IBD Standards. Half of the nurses had been employed for &lt;5 yrs (54%) and were in their first specialist nursing role. A quarter (25.8%) held no formal qualification at degree level. 55% make decisions to prescribe, drug type, dosage and treat. Over the 10-day audit period 6472 calls were taken through telephone advice lines, 3256 patients were seen in outpatient clinics, 112 in-patients with IBD were reviewed by the nurse specialists and 1203 patients attended to the nursing service for day case treatment. Services provided included education, telephone, inpatient/outpatient follow-up and management of biologic services. Advanced nursing practice, nurse led clinics and non-medical prescribing was identified. Two thirds of IBD nurse specialist services are suspended when the IBD nurse is away. Extrapolating daily over a 12 month period the data shows IBD nurses provide 28 980 patient episodes per year and work on average 33 min extra per day, equates to a minimum £347 200 per year. <h3>Conclusion</h3> IBD nurses in the UK are carrying out significant levels of activity influencing the management of considerable numbers of patients and play a fundamental role in complex medicine management. Roles are exclusively based in acute care and have other GI nursing roles alongside IBD. Recommendations are a review of education and training needs and further national audit of the quality of patient experience in relation to IBD nursing services. <h3>Competing interests</h3> None declared.
A Systematic Review and Network Meta-Analysis of Randomized Data on Efficacy of Novel Therapy Combinations in Patients with Lenalidomide Refractory Multiple Myeloma
Authors: Ghulam Rehman Mohyuddin, Jill Hampton, Muhammad Aziz, Sadik Khuder, Saad Ullah Malik, Brian McClune, Al-Ola Abdallah
Journal: Blood (2020)
Concurrent Care
Journal: Diabetes Care (1993)

Concurrent Care Diabetes mellitus is a disease that requires frequent medical attention.The hospitalization of a per-son with diabetes for an incurrent illness mandates ongoing medical evaluation and treatment of the diabetic state.Such close attention is best performed by a physician with special interest and expertise in diabetes.Thus, quality care for the hospitalized patient with diabetes usually requires concurrent care by a physician expert in diabetes and by a physician responsible for the patient's intercurrent illness.
From the author:
Authors: P. Lévy
Journal: European Respiratory Journal (2009)

treatment.This may be an important, yet frequently overlooked factor, partly explaining, along with the short follow-up period, why most studies failed to show a significant effect of CPAP treatment on glycaemic control and metabolic profile of OSA patients.Indeed, in the studies included in this article that have examined this parameter, there was a considerable variation of mean CPAP use (range 3.6-6.6h?night -1 ).Moreover, only two randomised studies exist in the literature comparing the effects of therapeutic versus subtherapeutic CPAP treatment [2, 3].In both studies, the average nocturnal therapeutic CPAP use was ,4 h.Specifically, it was 3.6 h in the study by WEST et al.[2] and 3.9 h in the study by COUGHLIN et al. [3].Hence, one may question whether insufficient CPAP use is a potential confounding factor in their negative findings.Conversely, we have recently demonstrated that CPAP use for .4h per night is crucial in ameliorating HbA 1c and total cholesterol levels along with several inflammation markers after 6 months of CPAP treatment in nondiabetic OSA patients [4, 5].Of note, it was exclusively shown in adherent patients that CPAP treatment had a beneficial metabolic effect [4, 5].Clearly, the role of adherence to CPAP therapy in these inconsistent results should be highlighted rather than underestimated.Given that there is no consensus on the minimum duration of CPAP use for a beneficial metabolic effect, further research is eagerly awaited to establish the optimal use of this modality for ameliorating the metabolic consequences in OSA patients.
Nebuliser therapy in the intensive care unit
Authors: M. O'Doherty, S. Thomas
Journal: Thorax (1997)

Departments ofto use systems which do not leak.There is also the circuit rather than immediately adjacent Nuclear Medicine, a need to determine the nebuliser outputs and to the endotracheal tube, 17 20 the absence of Haemophilia and Medicine, the particle size produced when attached to humidification, 21 22 activation during lung in-St Thomas' Hospital, short inspiratory triggered nebulisation.flation, 23 the use of larger bore endotracheal London Nebulisers used in ventilator circuits should tubes, 23 and a reduced lung inflation rate. 23and Department of not be left permanently in line and should be Nuclear Medicine, Kent and Canterbury cleaned and changed between nebulisations to Hospital, avoid small particle bacterial aerosols. 13Suitable Canterbury, Kent, UK   filters should be placed between the ventilator M J O'Doherty Jet nebulisers can be used during pressure limcircuit and the inspiratory and expiratory ports ited or volume cycled ventilation.During vol-Wolfson Unit of of the ventilator to protect the valves in the Clinical ume cycled ventilation the ventilator can only ventilator from the effects of deposited aerosol.Pharmacology, be driven during lung inflation.As the gas used University of to drive the nebuliser forms a proportion of the Newcastle, Newcastle-upon-Tyne patient's tidal volume, its volume and oxygen Methods of aerosol administration NE2 4HH, UK
Autopsy Frequency—United States, 1980-1985
Journal: JAMA (1988)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
278P Sequential chemotherapy with gemcitabine plus carboplatin, followed by additional docetaxel for advanced upper-tract urothelial cancer patient with impaired renal function
Authors: T. Yoneyama, T. Tanaka, T. Narita, M. Oikawa, K. Hagiwara, T. Yoneyama, A. Imai, S. Hatakeyama, Y. Hashimoto, T. Koie, C. Ohyama
Journal: Annals of Oncology (2016)
Nutrition/Metabolism
Authors: P. Dorao, J. L. Vazquez, F. Ruza, S. García, M. A. Delgado, C. Calvo, Jennifer J. Verhoeven, Jan A. Hazelzet, Koen F. M. Joosten, George Briassoulis, Shekhar Venkataraman, Ann Thompson, H. P. Leite, S. Iglesias, C. Faria, A. Ikeda, M. P. Albuquerque, W. B. Carvalho, Paolo Cogo, Giuseppe Giordano, Tamara Badon, Alberto Orzali, Luc Zimmerman, Pieter Sauer, Virgilio Carnielli, M. P. Champion, M. J. Marsh, R. N. Dalton, I. A. Murdoch, G. C. Morrison, T. Sajjanhar, Subir K. Chatterjee, Sugato Banerjee
Journal: Intensive Care Medicine (1996)
Role of Arginine Vasopressin in Regulation of Systemic Arterial Pressure
Authors: N. Rossi
Journal: Annual Review of Medicine (1986)

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of coronavirus disease 2019 (COVID-19), emerged in China in December 2019 and quickly spread around the globe, killing more than 4 million people and causing a severe economic crisis. ...Read More