tbuckley/cabot-search huggingface dataset:
THE ANTI TUBERCULOSIS INOCULATION TREATMENT OF RICHET.
Journal: JAMA (1891)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Psoriatic lesions in patients with chronic liver disease are distinct from psoriasis vulgaris lesions, as judged on basis of integrin adhesion receptors
Authors: Gianluigi Giannelli, Paola Savoia, Oronzo Schiraldi, Mario Lospalluti, Michele De Luca, Pier Carlo Marchisio, Vito Quaranta
Journal: Hepatology (1994)

ABSTRACT Psoriatic lesions are relatively frequent in patients with chronic liver disease. Furthermore, therapy with interferons tends to exacerbate the symptoms. The pathogenesis of psoriatic lesions is unclear. An important question is whether such lesions may be linked to the underlying chronic liver disease in these patients, or whether they are incidental manifestations of psoriasis vulgaris. We collected biopsy specimens from involved and uninvolved skin areas of chronic liver disease patients with psoriatic manifestations, as well as from psoriasis vulgaris patients, and investigated the patterns of integrin adhesion receptors by means of immunohistochemical methods. Integrin expression is known to be characteristically altered in psoriasis vulgaris. We found some of these changes in chronic liver disease psoriatic lesions — namely pericellular redistribution and suprabasal expression of the basement membrane receptor α6β4 and of the intercellular integrins α2β1 and α3β1. However, psoriasis vulgaris causes two other typical changes: One is the induction of the prototype fibronectin receptor α5β1, and the other is the alteration of integrin expression in areas of the epidermis that are macroscopically normal. These two changes were not found in chronic liver disease psoriasis biopsy specimens in 14 patients investigated. Thus integrin expression may be useful in differentiating chronic liver disease psoriatic lesions from psoriasis vulgaris lesions. Even though the two types of lesions are indistinguishable on inspection or by their histological features, they may be caused by distinct pathogenetic mechanisms. It remains to be seen whether the underlying chronic liver disease has a role, albeit indirect, in such mechanisms. (Hepatology 1994;20:56-65.)
Resistance to murine hepatitis virus strain 3 is dependent on production of nitric oxide . Multi Organ Transplant Program, The Toronto Hospital ? University of Toronto, Toronto, ON
Journal: Hepatology (1995)

A photometric microassay has been developed to quantitate macrophage Fc and C3b receptor mediated binding and phagocytosis by measuring the absorbance of macrophage associated erythrocytes at 405 nm on an automated densitometer. The method compares favorably in sensitivity and kinetics to the 51Cr-labeled erythrocyte assay. Saturation and linear dose response kinetics were demonstrable for both total index and phagocytic index of either Fc receptor or C3b receptor. The assay allowed detection of significant differences in Fc receptor function with varying macrophage densities and between Fc receptor competent (C3HeB/FeJ) macrophages and Fc receptor deficient (C3H/HeJ) macrophages. A valid binding index was derived at 37°C by computing the difference between the total and phagocytic induces, which compared favorably with binding studies at 4°C.This new procedure providese a simple, rapid and reproducible microassay for the quantitation of Fc/C3b receptor dependent binding and phagocytosis which offers distinct advantages over the laborious rosette assay and the 51Cr-labeled erythrocyte assay.
Influence Of Age On The Efficacy and Safety Of Dabigatran Versus Warfarin For The Treatment Of Acute Venous Thromboembolism: A Pooled Analysis Of RE-Cover and RE-Cover II
Authors: Sam Schulman, Henry Eriksson, Samuel Z Goldhaber, Ajay Kakkar, Clive Kearon, Sebastian M Schellong, Joerg Kreuzer, Nuala Peter, Jeffrey Friedman
Journal: Blood (2013)
Age-Related Macular Degeneration
Authors: José-Alain Sahel
Journal: New England Journal of Medicine (2008)

Age-related macula degeneration is the most common cause of visual disability in the industrialised world. The disease can be diagnosed as a maculopathy in 10-20% of the population over the age of 65. About 25% of these will have degeneration with reduced vision. Today, only a small proportion of patients with the aggressive wet form of the disease can be offered any therapy in the form of laser or photodynamic laser treatment. Worldwide epidemiological investigations designed to define contributing factors have so far not been conclusive, but the use of antioxidants and trace metals may be a useful prophylactic measure. Research into antiangiogenic therapy may also result in useful tools for ophthalmologists caring for this group of patients.
Multi-centered phase II trial of weekly 5-FU plus l-LV regimen as salvage line chemotherapy for oral fluorouracil resistant advanced gastric cancer (HGCSG1502)
Authors: Y. Sasaki, T. Muranaka, Y. Kawamoto, K. Sawada, H. Nakatsumi, K. Harada, T. Miyagishima, K. Hatanaka, M. Dazai, A. Ueda, T. Sasaki, K. Shinada, Y. Tsuji, S. Yuki, N. Sakamoto, N. Nishimoto, Y. Sakata, Y. Komatsu
Journal: Annals of Oncology (2019)
PRE-COLUMBIAN LEPROSY.
Authors: ALBERT S. ASHMEAD
Journal: JAMA (1895)

Dr. Muniz, of Lima, Peru, alone of all the authorities known to me, thinks that leprosy did exist among the Incas; he finds evidences of this in some ceramics, the<i>huacos</i>. In the<i>American Anthropologist</i>for January, there is an article entitled "The Huacos of Chira Valley, Peru," by Samuel Mathewson Scott. This vajley was once teeming with population, though scarcely populated now. In this part of the country, there are numerous ruins and graves, and Mr. Scott's excavations among these monuments of the past, enabled him to make a collection of Peruvian antiquities, now in the Museum of the University of Pennsylvania at Philadelphia. All the pottery found in those burial grounds are called<i>huacos</i>. They are found by the side of the mummies. "About the heads of the mummies, whether male or female, were ranged the pieces of pottery in black and red clay which are known as
Bleomycin in advanced squamous cell carcinoma: a random controlled trial. Report of Medical Research Council Working Party on Bleomycin.
Authors: K Halnan, T Brewin, N Bleehen, T Deeley, D F N Harrison, C Howland, A Johnson, G Ritchie, I Todd
Journal: BMJ (1976)

Bleomycin was compared with conventional cytotoxic drugs in the treatment of 70 patients with advanced squamous cell carcinoma; the primary deposit was in the head and neck in 50 patients and in the perineum or skin in 20. Thirty-four patients received bleomycin while 36 received other cytotoxic drugs. No significant difference was detected between the two groups either in the proportion showing tumour regression or in the survival rates. If bleomycin is to advance the treatment of squamous cell carcinoma it can be only in combination with other drugs or with radiotherapy.
Cushing's syndrome with amelioration during pregnancy
Authors: R. Lee
Journal: JAMA (1972)

A 30-year-old woman was found to have Cushing's syndrome two months prior to becoming pregnant. During her pregnancy she demonstrated both clinical and biochemical amelioration of her Cushing's syndrome starting about the 21st week of gestation and continuing to the time of delivery. At 34 weeks she was delivered of a healthy, premature female infant who is now 4 years old and thriving. About 7 months postpartum the mother again demonstrated florid hypercortisolism. At surgery, bilateral adrenocortical hyperplasia was found and a total adrenalectomy was performed. Postoperatively, the patient's clinical state gradually returned to normal. She has remained well receiving conventional hormone replacement. Women with Cushing's syndrome have difficulty in conceiving and in maintaining pregnancy. To our knowledge, this is the first report of amelioration of Cushing's syndrome during pregnancy.
Paracelsus.
Authors: L. Harrison Mettler
Journal: JAMA (1896)

Chicago, Oct. 19. 1896. <h3>To the Editor:</h3> —On page 879 ofThe Journalis a clipping which presents the life and character of Paracelsus in some what too roseate a hue. When I was at Salzburg in 1889, admiring the quaint picturesqueness of the town, reviving memories of Mozart and wondering at the modern troglodytes residing in furnished apartments cut cave-like out of the solid rock in the hillside, I naturally, as a physician, hunted up the relics of Paracelsus. The monument and chapel described in the clipping are easily discovered. Of much more interest to me, however, was the home of this curious character. At one end of the Salzach bridge and within hailing distance of the home of Mozart, stands upon a projecting corner, facing a kind of little square, a plain, flat, unornamental four-storied house, with a large portrait and explanatory plate in regard to Paracelsus on
Incorrect Authorship.
Journal: JAMA (1997)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Commentaire de travail de BS Lee et al., pp. 291
Journal: Endoscopy (2014)

See also: Midazolam with meperidine and dexmedetomidine vs. midazolam with meperidine for sedation during ERCP: prospective, randomized, double-blinded trialEndoscopy 2014; 46(04): 291-298DOI: 10.1055/s-0033-1358909
Aggression
Authors: Saul Rosenzweig
Journal: JAMA (1975)

Violence, like the weather, is discussed by everyone these days but is rarely altered by mere discussion. When, however, the discussion is based on scientific work oriented to medical and other social goals, practical results may be hopefully expected. It is a sign of the times that discussions of this kind are becoming more frequent. The recently organized International Society for Research on Aggression epitomizes this trend. The present volume is the fruit of a series of sessions held in 1972 under the auspices of the Association for Research in Nervous and Mental Disease. The contributions rest on a broad, humanistic conception of medicine and represent the whole gamut of the behavioral sciences—physiology, neurology, psychiatry, psychopharmacology, ethology, psychology, and sociology. The contributors included such outstanding individuals as Iranäeus Eibl-Eibesfeldt, John Spiegel, Lauretta Bender, Lawrence Kolb, Vernon Mark, and Ramsey Clark. Among the discussants were Philip Bard, Franco Ferracuti, Jerome Frank,
Sex and mental health on the campus
Authors: S. L. Halleck
Journal: JAMA (1967)

There is general agreement that sexual attitudes and sexual practices in American society are undergoing radical changes. I propose to examine the extent of these changes and to describe their impact upon the mental health of university students. My approach while hopefully not moralistic will not be free of value judgments. Like most psychiatrists I consider mental health to be something more than mere adjustment to the needs of the community. Mental health is defined according to certain values, values such as psychological comfort, intimacy, compassion, social responsibility, and self-knowledge. Once the psychiatrist begins to ask if a given sexual behavior is good or bad for a person's mental health he is no longer in a position to avoid making ethical judgments. How much change has there been in sexual attitudes and behaviors among university students? Recent surveys suggest that there have been important changes in students' attitudes toward premarital
Softball Sliding Injuries
Authors: David H. Janda
Journal: JAMA (1988)

In a previous retrospective study, base sliding was found to be responsible for 71% of recreational softball injuries. As most injuries occurred following rapid deceleration impact against stationary bases, quick-release (breakaway) bases were evaluated as a means to modify this mechanism of injury. Six hundred thirty-three softball games were played on breakaway-base fields and 627 games were played on stationary-base fields. Forty-five sliding injuries (7%) occurred on the stationary-base diamonds and only two sliding injuries (&lt;1%) occurred on the breakaway-base fields. Implementing the use of breakaway bases in recreational softball leagues could potentially achieve a significant, cost-effective reduction of injuries. (<i>JAMA</i>1988;259:1848-1850)
Treating refractory epilepsy in adults
Journal: BMJ (2006)

increased administration of fentanyl or diazepams to pregnant women, which increase risks to the women and costs to the health provider, undermine the interests of the women and are unnecessary for fetuses, who have not yet reached a developmental stage that would support the conscious experience of pain.I thank Peter Gianaros for critiquing an earlier version of this manuscript, Ian Apperly
Passive smoking and otitis media with effusion.
Authors: G. Barr
Journal: BMJ (1992)

It is therefore disquieting that manifestly disorders and to assess the response to hormone We found that 14% of our patients had fibro- inappropriate confidence intervals, presented by replacement therapy.For each.patient 10 somatic myalgia, and low oestrogen concentrations were Paul J Turnbull and colleagues in their paper and psychosomatic menopausal symptoms were seen in those with persistent symptoms.Gestrogen on the prevalence of HIV infection among ex-graded 0-3 (0= none, 3=severe).The pain scores withdrawal lessens rapid eye movement sleep and prisoners, passed the editorial process.'The usual (graded 0-3 for each joint) that had been sympto-heightens depression,' both of which are associated asymptotic formula of p± 1-96 SE, which produces matic for three months within the past three years with fibromyalgia, and hormone replacement a symmetric interval, yields inappropriate limits were totalled.Patients completed visual analogue therapy seems a logical option in this group.for proportions such as prevalences when the scales for pain (0-10O cm) and were examined by the Although there is undoubtedly a strong placebo number of positive results is low: a negative lower same observer for evidence of rheumatic disorders.effect with hormone replacement therapy' and limit can occur, uninterpretable as a "margin of joints were scored for tenderness (0-3).The carpal our study was uncontrolled with few patients, error."When the observed proportion is 0 the tunnel syndrome was diagnosed according to the hormone replacement therapy seemed to be highly symmetric method produces the interval 0 to 0, criteria of the American State Health Department,' efficacious in many patients, suggesting the need irrespective of the preset confidence interval; and one point was scored for the presence of each of for further randomised studies.Many common Turnbull and colleagues have shied away from Tinel's and Phalen's signs and median nerve rheumatological disorders, including the carpal quoting this degenerate interval for the prevalence sensory loss in each arm (maximum 6).Modified tunnel syndrome, seen in middle aged women in homosexual/bisexual men (0 out of 20 sampled), criteria of Yunus et al were used to diagnose may be part of the climacteric syndrome, for for which an upper limit of zero is singularly fibromyalgial and a count of tender points used which hormone replacement therapy should be inappropriate.(0-14).Patients were then assessed by a gynae-encouraged.An "exact" but more complex method is recoin-cologist, and oestrogens (subcutaneous implant, GERARD M HALL mended for small samples and proportions away transdermal patch or cream, or oral treatment) TIM D SPECTOR from 0-5.' For sample sizes up to 100 this method is were started.Progestogens were prescribed when St Bartholomew's Hospital, used by the program CIA,' and tabulations are appropriate.Patients were reassessed after SiX London ECIA 7BE available.'For sample sizes above 100 when the months with the same clinical evaluation, and
Hematologic changes in a patient with Hodgkin's disease in relapse
Authors: A. D. Ginsburg
Journal: JAMA (1977)

A patient with Hodgkin's disease also had anemia, hypochromia, and thrombocytosis, which were clues to an otherwise silent relapse. These features were corrected following chemotherapy. Repeated lymphangiography is shown to be of value in diagnosis. (<i>JAMA</i>238:1272-1273, 1977)
Liposomes in Silicosis Investigations
Authors: G. Erdogdu, V. N. Hasirci
Journal: Environmental Health Perspectives (1983)

The effects of quartz and sodium metasilicate on liposomes were studied in order to understand the mechanism of silicosis. 8-Hydroxyquinoline-5-sulfonic acid was tested for its in situ silicosis-prevention capacity. Two types of liposomes--(A) those incorporating cholesterol and (B) those without cholesterol--were used. The tests consisted of measuring permeability changes caused by the above-mentioned chemicals. Permeabilities were found to depend on membrane composition. Tests on quartz action led us to the conclusion that liposomes of this composition did not simulate the erythrocytes very well. It was also observed that absence or presence of cholesterol and the mode of contact altered the effect of quartz. Silicate destabilized type A liposomes, but this was less than that caused by quartz. This was explained by the concentration of monosilicic acid that dissolves out from quartz and silicate. When quartz was pretreated with the preventive, the type A liposomes were stabilized, but a slight destabilizing effect was observed on type B. 8-Hydroxyquinoline-5-sulfonic acid augmented the destabilizing effect of silicate, whereas it decreased the hemolytic activity of uncoated quartz, indicating a preventive potential in in vivo.
Folate levels and neural tube defects. Implications for prevention
Authors: L. E. Daly
Journal: JAMA (1995)

Using data from a recent case-control study, a woman's risk of having a child with a neural tube defect (NTD) was found to be associated with early pregnancy red cell folate levels in a continuous dose-response relationship. These findings were used to calculate the reduction in NTD cases that would be expected under two different strategies to raise folate levels. Targeting high-risk individuals has a small effect on the population prevalence but can substantially change an individual's risk. Targeting the population produces a small change in individual risk but has a large effect on the population prevalence. Supplementation of high-risk women would be the most efficient method to implement the high-risk strategy, while food fortification would be preferable for the population approach. The current guidelines for the prevention of NTD are for an increased folic acid intake of 0.4 mg per day. This would result in a 48% reduction in NTDs, which may be near optimal. The two intervention strategies should be considered complementary in prevention of NTDs. (<i>JAMA</i>. 1995;274:1698-1702)
Selective Renal Arteriography in the Diagnosis of Renal Hypertension
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal