tbuckley/cabot-search huggingface dataset:
A Short Practice of Surgery
Journal: JAMA (1949)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Amphetamine Prescribing
Authors: G. Patey
Journal: BMJ (1967)

Laboratory (S.E.R.L.) at Baldock is to be congratulated on its development work on neutron generator tubes.It is no easy task to increase the output of D-T (deuteriumtritium) tubes, and the Baldock tubes with their present output of 10" neutrons per second and a tube life of the order of 100 hours or so are considerably better than simi- lar tubes developed in other countries.
A clinical prediction model to assess risk for pancreatic cancer among patients with pre-diabetes.
Authors: Shimon Ben Boursi, Brian Finkelman, Bruce J. Giantonio, Kevin Haynes, Anil K. Rustgi, Andrew Rhim, Ronac Mamtani, Yu-Xiao Yang
Journal: Journal of Clinical Oncology (2018)

e16226 Background: A new diagnosis of diabetes mellitus (DM) has been observed within 2-3 years before the clinical presentation of a substantial proportion of sporadic pancreatic ductal adenocarcinoma (PDA) cases. The objective of the current study was to develop and internally validate a clinical prediction model for 3-year PDA risk among individuals with pre-diabetes defined as newly detected impaired fasting glucose (IFG). Methods: The study was conducted using the Health Improvement Network (THIN), a population-representative general practice medical records database from the UK. Eligible patients were aged ≥35 years, had a newly diagnosed IFG during follow-up and had ≥ 3 years of follow-up following the diagnosis of IFG. The dependent variable was incident PDA diagnosed within 3 years of IFG diagnosis. We evaluated a comprehensive list of PDA risk factors as well as variables related to glucose metabolism and performed multiple imputation for candidate predictors with missing values. We selected predictors using univariable analysis and a backward stepwise approach. A bootstrapping procedure was used for internal validation. Results: We identified 138,232 eligible patients with new-onset IFG. Among this cohort, 245 individuals (0.2%) were diagnosed with PDA within 3 years of IFG diagnosis. The median follow-up from IFG detection to PDA diagnosis was 326 days (IQR 120-588). The full multivariable prediction model included age, BMI, PPIs, total cholesterol, LDL, ALT and alkaline phosphatase. The AUC of the model was 0.71 (95%CI 0.67-0.75), and the p-value for the Hosmer and Lemeshow goodness of fit test was > 0.05. Internal validation of the model using bootstrapping procedure revealed minimal optimism of 0.001 (95%CI -0.009-0.01). Conclusions: We developed and internally validated a PDA prediction model based on clinical information routinely available at the initial appearance of IFG. This model exhibited good discrimination and calibration. The current model may substantially extend our ability to detect subclinical PDAs at an earlier stage when the tumor may potentially be more amenable to curative resection.
In Brief
Journal: JAMA (1967)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Mineral Waters of the United States and Their Therapeutic Uses. With an Account of the Various Mineral Spring Localities, Their Advantages as Health Resorts, Means of Access, etc., to which is added an appendix on potable waters.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Health educators turn to black community's leaders, organizations, other strengths
Authors: C. M. Olson
Journal: JAMA (1989)

THE BLACK COMMUNITY has characteristics that health educators say can be used to foster its members' well-being, although they add that it has other characteristics that pose particular problems to health education. An example of a useful characteristic is that existing leaders and organizations in the black community have already earned people's confidence, says Helene D. Gayle, MD, MPH, of the Centers for Disease Control, Atlanta. They provide valuable assistance in disseminating health information. The black church is a prominent example, adds John W. Hatch, MSW, DPH. As one of the few organizations controlled by blacks, it mirrors the pattern of influence within the black community. Hatch developed the Fitness Through Churches project in Durham, NC, in 1985, to combat cardiovascular disease. Selected members of 14 innercity congregations were taught to be health advocates, organizing and instructing exercise programs (<i>Hygie</i>1986;5[3]:9-12). Their training includes aerobic exercise along with information on
Book reviews
Authors: Charles R. Darley
Journal: British Journal of Dermatology (2004)

Journal Article Book reviews Get access Charles R. Darley Charles R. Darley Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 150, Issue 6, 1 June 2004, Page 1233, https://doi.org/10.1111/j.1365-2133.2004.05906_1.x Published: 01 June 2004
Illness related deception: social or psychiatric problem?
Authors: Christopher Bass, Peter W Halligan
Journal: Journal of the Royal Society of Medicine (2007)

In this paper we question the validity of factitious disorder as a meaningful psychiatric diagnosis. When the diagnosis is used there is often the assumption that the person engaging in the ‘deception’ is not lying in the traditional sense of being deliberately misleading. Moreover, little is known about the aetiology or psychopathology underlying factitious disorder, and the legitimacy of deception as a mental disorder has been questioned. It is argued that while illness deception may be more common that hitherto assumed, factitious disorder as a distinct type of psychiatric disorder is conceptually flawed, diagnostically impractical and clinically unhelpful and should be dropped from existing nosologies.
Fritz Spiegl's MuSick Notes--A Medical Song Book
Authors: J S P Lumley
Journal: Journal of the Royal Society of Medicine (2002)

The Future of LifeIn ecology, as in medicine, a wrong diagnosis can cause far more harm if it is negative than if it is positive-E O Wilson 1 .In 1987, a UN-appointed commission chaired by former general practitioner Gro Harlem Brundtland (at the time Prime Minister of Norway and now Director General of the World Health Organization) published its report, Our Common Future 2 .It introduced into common parlance and political consciousness the notion of 'sustainable development', defined as 'Development that meets the needs of the present without compromising the ability of future generations to meet their own needs'.It was not a new concept; its modern root is probably a World Council of Churches' recognition that the longstanding aim of 'peace with justice' could not be achieved without caring for the environment (or 'Creation' in religious language).The UK submission to the Earth Summit in Rio 3 in 1992 took this up and emphasized the ethical nature of sustainable development: 'We have a moral duty to look after our planet and to hand it on in good order to future generations.That is what the experts mean when they talk of ''sustainable development'': not sacrificing tomorrow's prospects for a largely illusory gain today.We must put a proper value on the natural world: it would be odd to cherish a Constable but not the landscape he depicted'.Crispin Tickell has described sustainable development as 'treating the Earth as if we mean to stay', John Selwyn Gummer defines it as 'not cheating on our children'.Sustainable development is not uncontentious.Conventional economists tend to dismiss it, usually on the grounds that they want 'sustainable growth', which is an oxymoron since growth requires the input of new resources.However, it has been increasingly embraced ever since we began to get pictures of our finite globe from space ('Spaceship Earth'), with implicit limits to its resources.It has also become increasingly necessary.As Pimm comments 4 , 'Human beings use 40 percent of annual terrestrial plant growth, 60 percent of accessible freshwater runoff, and 35 percent of the oceans' continental shelf productivity.These are large figures, especially since our population will likely double by midcentury'.Ed Wilson has formed and led thought on sustainable development for the last two decades.A distinguished Harvard biologist (he is the leading international authority on ants), he revolutionized thinking on human behaviour by popularizing in his book Sociobiology (1975) a mechanism,
Reply:
Authors: Jonel Trebicka, Tilman Sauerbruch, Jörg Heller
Journal: Hepatology (2007)

We thank Zamora-Valdes and colleagues for their note of caution. We agree completely that our results can not be extrapolated to humans. Nevertheless, they open the discussion on new medical treatments of liver cirrhosis. There are probably species-specific differences with respect to the dose of atorvastatin. For our study, we used a dosage of 15 mg/kg/day. An even higher dosage of atorvastatin1-3 has been used in rat models in the field of cardiovascular research. It is correct that serum cholesterol levels may be high in patients with cholestasis, especially in patients with primary biliary cirrhosis. Interestingly, serum cholesterol levels did not increase after bile duct ligation in our model (Bile duct ligation = 63.8 ± 5.6 versus controls = 66.2 ± 4.2 mg/dL). We understand the concerns with respect to a cholesterol-lowering therapy in patients with cirrhosis, although the points raised in the correspondence may appear a bit far-fetched. Yet all these issues, among others, have to be considered in case of planning a study on the application of statins to influence the course of chronic liver disease in humans. Such studies on drugs that potentially may influence liver cirrhosis and/or portal hypertension are certainly warranted because our armamentarium is limited. Jonel Trebicka M.D.*, Tilman Sauerbruch M.D.*, Jörg Heller M.D.*, * Department of Internal Medicine I, University of Bonn, Bonn, Germany.
Letters to the Editor
Authors: Jacqueline Whang-Peng, M.D.
Journal: JNCI Journal of the National Cancer Institute (1971)

Journal Article Letters to the Editor Get access Jacqueline Whang-Peng, M.D. Jacqueline Whang-Peng, M.D. Senior Investigator Human Tumor Cell Biology Branch National Cancer Institute Bethesda, Maryland 20014 Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 46, Issue 3, March 1971, Pages 686–687, https://doi.org/10.1093/jnci/46.3.686 Published: 01 March 1971
Association of Gleason 9-10 prostate cancer with worse outcomes compared to Gleason 8 disease.
Authors: Che-Kai Tsao, Kathryn P. Gray, Mari Nakabayashi, Caroline Evan, Matt D. Galsky, Philip W. Kantoff, William K. Oh, Mark Pomerantz
Journal: Journal of Clinical Oncology (2013)

157 Background: Use of pathological Gleason score for risk stratification of localized prostate cancer is widely accepted. However, data are lacking regarding differences in presentation and outcome among those with Gleason 8-10 disease. Methods: Using the Dana-Farber Cancer Institute Prostate Clinical Research Information Systems database, we identified a cohort of patients with biopsy Gleason 8-10 disease who received definitive radical prostatectomy (RP) or radiation therapy (RT) (external beam or brachytherapy) for curative intent. The study endpoints, time to biochemical recurrence (BCR), time to metastatic disease (MD), and overall survival (OS) were estimated using the Kaplan-Meier method. Cox proportional hazards model was used to investigate the association of the study endpoints and Gleason score groups (8 vs. 9 and 10) adjusted for clinical and pathological factors including age, PSA at diagnosis, type of local therapy, and tumor stage. Results: We identified 848 patients who received either local definitive RT (n=411) or RP (n=437). Median follow-up from diagnosis was 5.3 years. Patient characteristics at diagnosis (race, age, and clinical stage) were similar between the two groups (Gleason 8 vs. Gleason 9-10). Patients with Gleason 9-10 disease were more likely to receive radiotherapy as primary local therapy (58% vs. 46%, p=0.001), and to receive hormonal therapy as a part of their definitive treatment course (64% vs. 48%, p&lt;0.001). Patients with Gleason 9-10 disease had shorter time to BCR, time to MD, and a trend towards worse OS using multivariate analysis adjusted for significant clinical and pathological factors. (Detailed in table below). Conclusions: In our study, we found that patients with localized Gleason 9-10 disease who were treated with definitive therapy with curative intent had worse outcomes compared to patients with Gleason 8 disease. More aggressive, multimodality treatments may be indicated for men diagnosed with the highest Gleason grades. [Table: see text]
Stem cell transplantation
Authors: Martin Höglund
Journal: HemaSphere (2018)

Uppsala University Hospital, Sweden This is an open access Abstract Book distributed under the Attribution-NonCommercial-NoDerivs (CCBY-NC-ND), which allows third parties to download the abstracts and share them with others as long as they credit the author and the abstract book, but they cannot change the content in any way or use them commercially. http://creativecommons.org/licenses/by-nc-nd/4.0
PATENT MEDICINES CONTAINING ALCOHOL BARRED IN SOUTH CAROLINA.
Journal: JAMA (1904)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hyperprolactinemia associated with empty sella syndrome
Authors: T. H. Hsu
Journal: JAMA (1976)

SINCE the radioimmunoassay of human prolactin became available, hyperprolactinemia has been demonstrated in a number of pathological states.<sup>1</sup>An elevated basal prolactin concentration of more than 200 ng/ml is generally regarded as strong evidence in favor of an adenomatous pituitary lesion.<sup>2</sup>Our patient had substantial hyperprolactinemia associated with the empty sella syndrome. <h3>Report of a Case</h3> A 37-year-old woman was referred to The Johns Hopkins Hospital in December 1973 because of persistent generalized headaches of five years' duration. Three years prior to admission, she underwent extensive examinations in another hospital. Skull roentgenograms had shown enlargement of the sella turcica, with erosion of the dorsum sellae (Fig 1). A right brachial arteriogram showed no abnormalities. Pneumoencephalography was attempted twice, but no air could be driven into the ventricular system (Fig 2). The patient was obese, normotensive, and without visual field defects. Galactorrhea could not be demonstrated. Serum thyroxine level
Erratum
Journal: JNCI Journal of the National Cancer Institute (1968)

In “Role of Bone Marrow in Induction of Thymic Lymphomas by Neonatal Injection of 7,12-Dimethylbenz[a]anthracene” by J. K. Ball, volume 41, number 2, August 1968, page 556, the last sentence of the first paragraph under “Discussion” should read: Results from preliminary experiments indicate that the neonatal injection of 10 μg of DMBA does result in a decrease in thymus weight beginning approximately 10 days after DMBA.
Update in Critical Care Medicine
Authors: Kalpalatha K. Guntupalli, Robert E. Fromm
Journal: Annals of Internal Medicine (2000)

Updates from the Annual Session15 February 2000Update in Critical Care MedicineKalpalatha K. Guntupalli, MD and Robert E. Fromm Jr., MD, MPHKalpalatha K. Guntupalli, MDFrom Ben Taub General Hospital and Baylor College of Medicine, Houston, Texas.Search for more papers by this author and Robert E. Fromm Jr., MD, MPHFrom Ben Taub General Hospital and Baylor College of Medicine, Houston, Texas.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-132-4-200002150-00007 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail We begin this survey with reports describing advances in mechanical ventilatory assistance, including maximization of oxygenation by inhaled nitric oxide and a lung-protective ventilatory regimen that seems to improve the outlook for patients with the acute respiratory distress syndrome (ARDS). We also discuss extubation, both planned (by use of a simple index of readiness) and unplanned. Reports dealing with sepsis and infection cover the detection of Pneumocystis carinii infection by endotracheal aspiration and the dependence of survival on how well a patient can utilize oxygen. Another topic covered is the value of gastrointestinal decontamination in the intensive care unit (ICU). ...References1. Yang KL, Tobin MJ. A prospective study of indexes predicting the outcome of trials of weaning from mechanical ventilation. N Engl J Med. 1991;324:1445-50. CrossrefMedlineGoogle Scholar2. D'Amico R, Pifferi S, Leonetti C, Torri V, Tinazzi A, Liberati A. Effectiveness of antibiotic prophylaxis in critically ill adult patients: systematic review of randomised controlled trials. BMJ. 1998;316:1275-85. CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Kalpalatha K. Guntupalli, MD; Robert E. FrommJr., MD, MPHAffiliations: From Ben Taub General Hospital and Baylor College of Medicine, Houston, Texas.Corresponding Author: Kalpalatha Guntupalli, MD, Baylor College of Medicine, Pulmonary Department, Ben Taub General Hospital, 1502 Taub Loop, Houston, TX 77030.Current Author Addresses: Dr. Guntupalli: Baylor College of Medicine, Pulmonary Department, Ben Taub General Hospital, 1502 Taub Loop, Houston, TX 77030.Dr. Fromm: Baylor College of Medicine, 6565 Fannin Street, MSM 196, Houston, TX 77030. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 15 February 2000Volume 132, Issue 4Page: 288-295KeywordsAcute respiratory distress syndromeAutopsyExtubationHemorrhageHeparinIntensive care unitsOxygenPulmonary embolismRelative riskWeaning ePublished: 15 August 2000 Issue Published: 15 February 2000 Copyright & PermissionsCopyright © 2000 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Incorrect Price and Incorrect Contact Address.
Journal: JAMA (1996)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal