tbuckley/cabot-search huggingface dataset:
Possibilities of Detecting Health Effects by Studies of Populations Exposed to Chemicals from Waste Disposal Sites
Authors: Patricia A. Buffler, Martin Crane, Marcus M. Key
Journal: Environmental Health Perspectives (1985)

Factors affecting the design of an epidemiologic study assessing possible health effects from chemical waste disposal sites are reviewed. Such epidemiologic studies will most likely be prompted either by a known release of chemicals into the environment around the site, or by an unusual disease cluster in a population near the site. In the latter situation, a method for evaluating the health effects is needed, and one possible approach is discussed. In the former situation, it may not be obvious what health outcomes are relevant. Reported associations between health effects and chemicals in humans were reviewed. Studies from the occupational and environmental literature were classified by chemical and target organ affected and presented in tabular form. No attempt was made to critically evaluate the quality of evidence for each health effect, although bibliographic documentation was provided where possible. Episodes of chemical contamination of food, drinking water and other media were also reviewed and presented in a separate table. The organ sites likely to be affected by toxic chemicals from waste disposal sites depend heavily on the route of exposure and the dose that is received. Ingestion is the most frequently reported route of exposure in episodes of environmental contamination. These have affected the hepatic, renal, hematopoietic, reproductive, and central nervous systems. The type and severity of effects were dose-dependent. Direct skin contact is important in the occupational environment where dermal and central nervous system effects have been reported but seems less likely as a route of exposure for populations around waste disposal sites. Inhalation, unless at relative high concentrations or as a result of fire, is unlikely to be important, although hematopoietic, reproductive, and central nervous system effects have been reported in occupational studies.
A CASE OF TRUE PNEUMOTYPHUS
Journal: JAMA (1922)

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CNS Effects and Abuse Liability of Anabolic-Androgenic Steroids
Authors: S. E. Lukas
Journal: The Annual Review of Pharmacology and Toxicology (1996)

Over the past two decades, deadly coronaviruses, with the most recent being the severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) 2019 pandemic, have majorly challenged public health. The path for virus invasion into humans and other ...Read More
Memoires de l'Academie de Chirurgie, Paris
Journal: JAMA (1966)

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Pfluegers Arch f d Ges Physiologie, Berlin
Journal: JAMA (1964)

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AMA Insights
Journal: JAMA (1987)

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SYMPATHETIC RAMISECTION FOR THE RELIEF OF SPASTICITY
Journal: JAMA (1926)

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ADENOMA OF MUCOUS GLANDS OF MOUTH, AND MACROCHEILIA
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
MEDICAL SIDE OF CAPITAL PUNISHMENT.
Journal: JAMA (1992)

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Report of the Librarian
Authors: Henry R. Viets
Journal: New England Journal of Medicine (1946)

WITH the end of the war and the return of men from the services, the Boston Medical Library is slowly regaining the position it held five years ago. By the beginning of 1946 the membership had already increased and had reached a total higher than that at any time in the history of the Library. During the year, the staff remained unchanged and the Library continued to function at a decreased pace but serving its clientele in what appears to have been a reasonably satisfactory manner. At least no major complaints were heard by the librarian and although many of . . .
Mir-34a as Part of the Chemotherapy Resistance Network in Chronic Lymphocytic Leukemia.
Authors: Thorsten Zenz, Julia Mohr, Eric Eldering, Arnon P Kater, Andreas Bühler, Dirk Winkler, Dirk Kienle, Jan Dürig, Daniel Mertens, Hartmut Döhner, Stephan Stilgenbauer
Journal: Blood (2008)
Coming to terms with indications for fetal surgery
Authors: C. Marwick
Journal: JAMA (1993)

IN THE 30 years since A. William Liley, MD, performed the first in utero blood transfusion to successfully treat erythroblastosis fetalis (at the National Women's Hospital, Auckland, New Zealand), interest has burgeoned in what has become something of a medical subspecialty—fetal medicine and surgery. Now, some investigators are taking a second look and saying that not all fetal abnormalities need to or should be treated in utero. Significant advances in the treatment of abnormalities of the fetus and newborn are opening the way to treat these infant patients at the most opportune time—and they may not necessarily involve treating the fetus. A variety of technologies contribute to this wait-and-see approach. Some are new. Others are applications of such existing modalities as ultrasound. For infants born at term, the procedures available include extracorporeal membrane oxygenation, hemofiltration to treat acute renal failure, and the investigational use of nitric oxide for various applications.
PUBLIC HEALTH.
Journal: JAMA (1896)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hypertension, bilateral renal artery stenosis, adrenocortical adenomas, and normal serum electrolyte levels
Authors: H. S. Bloch
Journal: JAMA (1966)

Aortography revealed bilateral renal artery stenosis in a patient with hypertension, diabetes mellitus, normal serum electrolyte levels, normal excretion of hydroxycorticosteroids, and increased excretion of aldosterone. Following an attempt at surgical correction of the stenosis, the patient died of a myocardial infarction. The autopsy revealed two adrenal adenomas which were morphologically indistinguishable from aldosterone-producing tumors. Therefore, the patient's hypertension would most likely not have been cured by correction of the renovascular lesions alone. Because concurrence of primary aldosteronism and renal artery stenosis is probably not rare, it is suggested that patients with renal artery stenosis be explored for adrenal adenomas prior to correction of the stenosis.
Uncomplicated
Authors: Nadia Glasgow
Journal: JAMA (2018)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Zinc as a cofactor in human immunodeficiency virus-induced immunosuppression
Authors: J. Falutz
Journal: JAMA (1988)

<h3>In Reply.</h3> —Drs Moskowitz and Arsura raise several important points concerning the diagnosis and management of<i>Pneumocystis</i>pneumonia to which we would like to respond. First, while silver-methenamine and Giemsa staining of bronchoalveolar lavage specimens are highly sensitive for diagnosing PCP, in published series the yield is only about 90% to 95%.<sup>1</sup>We have recently noted, however, that the sensitivity of bronchoalveolar lavage testing is increasing, perhaps reflecting the greater experience of our laboratory staff. In our institution, patients suspected to have PCP with negative bronchoalveolar lavage specimens undergo repeated bronchoscopy with transbronchial biopsy, a procedure that increases the diagnostic yield to 100%.<sup>1</sup>Second, response to antimicrobial therapy in patients with PCP is usually gradual, with defervescence and a reduction in dyspnea occurring on average after five to seven days of therapy.<sup>2,3</sup> A rapid response to sulfamethoxazole and trimethoprim in a patient with negative bronchoalveolar lavage stains,
<i>Errata</i>: Vol. 65, No. 39
Journal: MMWR Morbidity and Mortality Weekly Report (2016)

For the report, "Vaccination Coverage Among Children in Kindergarten - United States, 2015-16 School Year," on page 1061, the third sentence of the second full paragraph should read, "For example, the California Department of Public Health worked to improve vaccination coverage at schools identified from local-level data as having high levels of provisional enrollment." In addition, the fifth sentence of the same paragraph should read, "As a result, from 2014-15 to 2015-16, the number of provisionally enrolled kindergartners decreased from 36,731 (6.9%) to 24,424 (4.4%), MMR coverage increased from 92.6% to 94.5%, and DTaP coverage increased from 92.4% to 94.2% (4)."
Abstract 16640: Prognostic Importance of Pulmonary Hypertension Severity by Invasive Hemodynamics in Patients With Severe Aortic Stenosis
Authors: Joao L Cavalcante, Andrew Althouse, Ryan Campbell-Massa, Mitika Maddula, Thomas G Gleason, William Katz, Frederick Crock, Matthew Harinstein, Forozan Navid, Dustin Kliner, John T Schindler, Joon S Lee
Journal: Circulation (2015)

Introduction: The prevalence and impact of pulmonary hypertension (PH) severity on clinical outcomes for patients with severe AS is unclear and controversial. Our goal was to compare the correlation of mortality to degree of PH as measured by transthoracic echocardiography (ECHO) versus invasive hemodynamics (CATH). Methods: Retrospective data collection of patients with severe aortic stenosis (AV area index ≤ 0.6 cm2/m2) and measured pulmonary artery systolic pressure (PASP) by ECHO and CATH within 60 days of one another from 2010-2014. According to guidelines, patients were classified as having no PH (PASP&lt;35mmHg), mild PH (PASP 35-45mmHg), moderate PH (PASP 46-59mmHg), and severe PH (PASP≥60mmHg) by each method. Multivariate Cox-proportional hazard model was used for risk-adjustment comparisons. Results: A total of 186 patients were identified with mean age of 77 ± 10 years, 62% male and 38% diabetic. The median time difference between the 2 procedures was 4 days (IQR: 1-13 days). After a median follow-up of 18 months (IQR: 5-27 months), there were 63 deaths (34%). Moderate/Severe PH was prevalent by either ECHO or CATH (47% vs. 62%, p&lt;0.0001, respectively) although with modest agreement between ECHO and CATH PH severity (kappa=0.37). Both PH severity assessments were strongly associated with mortality; however, CATH showed better stratification with moderate PH associated with equally significant mortality risk (Figure 1). After adjustment for AVR (HR=0.23, 95% CI 0.11-0.48,p&lt;0.01), age, gender, BMI, diabetes, and NYHA class, presence of moderate PH by CATH remained associated increased mortality risk (HR=2.25, 95% CI 1.04-4.89, p=0.04). Conclusions: Moderate or greater PH is common among severe AS patients and is more commonly diagnosed by CATH. Ascertainment of PH severity by CATH is important as even moderate PH correlates with increased 1-yr mortality despite adjustment for AVR and other comorbidities.
Leads from the MMWR. Drownings--Georgia, 1981-1983
Journal: JAMA (1985)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
SLEEPING SICKNESS.
Journal: JAMA (1907)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal