tbuckley/cabot-search huggingface dataset:
Obituaries
Authors: Farrell Kramer
Journal: JAMA (1989)

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Feasibility of long-term patient reporting of toxicities from home via the internet during routine chemotherapy.
Authors: Timothy J Judson, Antonia V Bennett, Lauren J. Rogak, Laura Sit, Allison Barz, Mark G. Kris, Clifford Hudis, Howard I. Scher, Paul Sabbatini, Deborah Schrag, Ethan M. Basch
Journal: Journal of Clinical Oncology (2013)

6575 Background: Patient-reported outcomes are increasingly used in routine outpatient cancer care to guide clinical decisions and enhance communication. Prior evidence suggests good patient compliance with reporting at scheduled clinic visits, but there is limited evidence about compliance with long-term longitudinal reporting between visits. Methods: Patients receiving chemotherapy for lung, gynecologic, genitourinary or breast cancer at a tertiary cancer center, with access to a home computer and prior email experience, were asked to self-report seven symptomatic toxicities via the web between visits. Email reminders were sent to participants weekly; patient-reported high-grade toxicities triggered email alerts to nurses; printed reports were provided to oncologists at visits. A priori threshold criteria were set to determine if this data collection approach merits further development, based on monthly compliance rates (75% or more participants reporting at least once per month on average) and weekly compliance rates (60% at least once per week). Results: Between September 2006 and November 2010, 286 patients were enrolled (64% female, 88% white, median age 58). Mean follow-up was 34 weeks (range 2-214). On average, monthly compliance was 83% and weekly compliance was 62%, without attrition until the month prior to death. Greater compliance was associated with older age and higher education, but not performance status. Compliance was greatest during the initial 12 weeks. Symptomatic illness and technical problems were rarely barriers to compliance. Conclusions: Monthly compliance with sustained home web reporting is high, even with only weekly email reminders, but weekly compliance is lower, warranting strategies to enhance compliance in routine care settings. Barriers are likely surmountable through further use of reminder systems and questionnaire access via portable media. Between-visit symptom reporting may lead to more patient-centered care, enhanced quality, and improved patient satisfaction. Clinical trial information: NCT00578006.
AMA Archives Journals Abstracts
Journal: JAMA (1996)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Local expression of B7-H1 promotes organ-specific autoimmunity and transplant rejection
Authors: Sumit K. Subudhi, Ping Zhou, Lisa M. Yerian, Robert K. Chin, James C. Lo, Robert A. Anders, Yonglian Sun, Lieping Chen, Yang Wang, Maria-Luisa Alegre, Yang-Xin Fu
Journal: Journal of Clinical Investigation (2004)

A number of studies have suggested B7-H1, a B7 family member, inhibits T cell responses. Therefore, its expression on nonlymphoid tissues has been proposed to prevent T cell–mediated tissue destruction. To test this hypothesis, we generated transgenic mice that expressed B7-H1 on pancreatic islet β cells. Surprisingly, we observed accelerated rejection of transplanted allogeneic B7-H1–expressing islet β cells. Furthermore, transgenic B7-H1 expression broke immune tolerance, as some of the mice spontaneously developed T cell–dependent autoimmune diabetes. In addition, B7-H1 expression increased CD8+ T cell proliferation and promoted autoimmunity induction in a T cell adoptive transfer model of diabetes. Consistent with these findings, B7-H1.Ig fusion protein augmented naive T cell priming both in vitro and in vivo. Our results demonstrate that B7-H1 can provide positive costimulation for naive T cells to promote allograft rejection and autoimmune disease pathogenesis.
Follicular psoriasis
Authors: L. STANKLER, S. W. B. EWEN
Journal: British Journal of Dermatology (1981)

This is a report on ten patients with follicular psoriasis. Two distinct clinical types could be distinguished. An adult form, seen especially in women, presented with widespread psoriasis in which follicular lesions occurred on both thighs as part of the efflorescence. Follicular lesions were aggregated to form isolated asymmetrical plaques on the trunks of children with inactive psoriasis. The histological findings in follicular psoriasis varied according to the age of the lesion. In the early lesion there was a marked dermal infiltrate in which the mast cells were prominent but the hair follicle appeared normal. Older lesions were found to have nucleated cells in the ostium of the follicle. These findings suggest that the hair follicle may be affected as part of psoriatic involvement of the integument.
Miscellanea Media
Journal: JAMA (1964)

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Doctor Gruffalo
Authors: Patrick Hutt
Journal: BMJ (2005)

<i>The Gruffalo</i> by Julia Donaldson is a famous children9s book—the story of a mouse who enters the woods and crosses paths with a monster. With over a million copies sold, a sequel written, and a film being made, what does this have to do with medicine? Julia is not a doctor but Malcolm Donaldson, consultant paediatrician and her husband, is. Both will be touring Europe next year with a show called “The Gruffalo and Friends”. <i>BMJ Careers</i> caught up with Malcolm to validate his medical performance Malcolm and Julia Donaldson will be appearing at the Edinburgh Book Festival on 20th-21st August and Hamley9s Piccadilly on 27th August
Bucolic Landscape
Authors: M. Therese Southgate
Journal: JAMA (1998)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
General practice premises
Journal: BMJ (1977)

Relation of lecithin :sphingomyelin ratio (LSR) to presence of vernix in amntiotic fluxid LSR I Total ;2 !2 1-3 >3 No vernix seen 17 12 4 33 Cloudy, with doubtful 0 4 8 12 presence of vernix Vernix definitely present 0 5 29 34 Total 17 21 41 79Z2= 3487; DF 4; P <0(001; contingency coefficient 0-55.LSR is sometimes found in clear amniotic fluid, no immature LSR (> 2) was seen whenever vernix was present.Our findings suggest that amnioscopy might be used to assess fetal maturity before induction of labour.Induction can proceed if vernix is seen in the amniotic fluid and amniocentesis for the measurement of amniotic fluid LSR need be performed only when no vernix is seen.
Classifying Steroids as Controlled Substances Suggested to Decrease Athletes' Supply, but Enforcement Could Be a Major Problem
Journal: JAMA (1987)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Contents page
Authors: Mark Johnson, Yuko Munakata, Richard Aslin, Jo ´zsef Fiser, Michael Posner, Mary Rothbart, B Casey, Nim Tottenham, Conor Liston, Sarah Durston, Joan Stiles, Judy Reilly, Brianna Paul, Pamela Moses, Daphne Maurer, Terri Lewis, Catherine Mondloch, Yuko Trendsin, Julian Ogilvie, Arthur Wadsworth, Manager Moulton
Journal: Trends in Cognitive Sciences (2005)
"BURKING" UP TO DATE.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Cyclosporine, in combination with other drugs, studied in insulin-dependent diabetes therapy
Authors: C. A. Raymond
Journal: JAMA (1988)

CYCLOSPORINE TRIALS in persons with insulin-dependent diabetes mellitus (IDDM) offer both good news and bad. The good news is that the results have cinched the role of autoimmune responses in the disease's pathophysiology, opening the way for better combined immunotherapies. The bad news is that the drug, at least as it is now being used, offers at most an extended honeymoon from insulin dependence. But when cyclosporine therapy is withdrawn, the honeymoon is over. In recent months, clinical investigators from around the world have been reporting the results of controlled trials of cyclosporine in patients with recent-onset IDDM. At such meetings as the 35th postgraduate course of the American Diabetes Association in Palm Desert, Calif, the Research and Clinical Frontiers of Diabetes meeting in St Louis, and the American Diabetes Association scientific session in Indianapolis, discussion of the results has centered on weighing the potential risks against the benefits. "With
Evaluation of postprandial hyperemia in superior mesenteric artery and portal vein in healthy and cirrhotic humans: An operator-blind echo-Doppler study
Authors: C Sabbá
Journal: Hepatology (1991)

In an operator-blind design, we used an echo-Doppler duplex system to examine superior mesenteric artery and portal vein hemodynamics on two consecutive mornings in 12 fasting cirrhotic patients and 12 matched controls, randomized to a standardized 355 kcal mixed-liquid meal vs. water. Cross-sectional area and mean velocity were recorded from the portal vein and superior mesenteric artery at 30 min intervals, from 0 min to 150 min after ingestion. Flows were calculated. Pulsatility index, an index related to vascular resistance, was obtained for the mesenteric artery. Baseline flows did not differ between cirrhotic patients and control patients, but pulsatility index was reduced in the cirrhotic subjects. Maximal postprandial hyperemia was attained at 30 min. Cirrhotic patients showed a blunted hyperemic response to food. In normal controls, portal vein area increased significantly after the meal from 30 min to 150 min, whereas in cirrhotic patients a significant difference occurred only at 30 min. Pulsatility index in both groups was significantly reduced after eating, and this reduction persisted up to 150 min. No changes after ingestion of water were observed. Echo-Doppler was very sensitive in detecting postprandial splanchnic hemodynamic changes and differences between cirrhotic patients and normal subjects. Mesenteric artery pulsatility index was more sensitive than flow in detecting baseline hemodynamic differences. In cirrhotic patients, portal postprandial hyperemia was mainly related to the increase in mean velocity. (HEPATOLOGY 1991;13:714–718.)
International Abstracts
Journal: JAMA (1992)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Weight of the Evidence on the Human Carcinogenicity of 2,4-D
Authors: M. A. Ibrahim, G. G. Bond, T. A. Burke, P. Cole, F. N. Dost, P. E. Enterline, M. Gough, R. S. Greenberg, W. E. Halperin, E. McConnell, I. C. Munro, J. A. Swenberg, S. H. Zahm, J. D. Graham
Journal: Environmental Health Perspectives (1991)

Ile plnoy herbici 2,44kbropb Wacetic adcd (2,4-D) i widely used toanrol the wthofwe s andbradleaf plants.VW convened a panel of 13 scientsts to weigh theevidence on the humancardnogenicity of2,4-D.The pand based its findings on a rview ofthe td oil andepAde a l literature on 2,4-D and related phenoxy herbicides.The toxiological data do not provide a strongbasisforp lgthat 2,4-D s a huancardnogen.Alhough a cause-effect relatlouship is fr from bdng _ d , the _evidn for an ao n beteen expose to2,4-D and non-Hodgkin's lymphoma is suggestive and requires futher i tion.There is little evidence ofan assocation between use of2,4-Dand soft-tssue sarcoma or Hodgkinsdesse, and no evdence ofanasstio nbet een2,4-Duseand any other form ofcancer.Scientiss on the panel were asked to categorize 2,4-D as a "known," "probable," "possible," or "unlikly" arnogenorasa
Lectures ON THE SYMPATHETIC INNERVATION OF STRIATED MUSCLE
Authors: J. I. Hunter
Journal: BMJ (1925)

England last Nov-ember lie was invited by the Uiniversity of Londclon to give tlhree advanced lectur es in anatomy, wh-lichl -ere to have been delivered in the second week of Deceniiber: but the large audience that assembled to hear the filrst lectur e wer-e imifornmed of the grave illness to which lie succumibed tw o days later (see BRITISH MEDICAL JOUERN-AL December 20tlh, 1924).He had been looking forw ard -itlh the keenest in4erest to the delivery of these lectures, becanise they -would have provided him the opportunity for clearing away the misunderstanding of his w-ork anid for demiionistratinig tlle adequacy and reliability of hiis e-idence amid the inferences he had drawin from it.In particular lhe w-as anxious to explain the scientific principlles that slhould guiide the surgeoni in the selection of l)atients foir the operation that lie had devised (in collaboration-with Dr. Noi-irman Rovle)for the rielief of certain patients subject to spastic l)ara- plegia-naimely, those whose voluntamy conitrol of mlutiscular actions was uniimpaired except for time interference resulting from an exaggeration of wh-bat Slieririmgton calls " plastic tone "; and it had been his initenitioni to describe time surgical procedure in so far as the reasonis for the choice of the rami to be cut were comncerned.III tIme third lecture lie proposed to discuss tIe discordant conlclusions that hiad been drawin by differenit plhysiologists amid surgeomls respectively frlom their experiiments (espe- cially in the cat) and operations oni tie sympathetic in lhumllani patients, and to give the explammation of this aplparent lack of comisistency.Finally, he imitended to deal with tile wider scientific bearings of his anatomical and experimental researches, and the possibilities thus opened up for promising investigationis in many.dir ectiomis-aniatoiimical, physiological, pharmacological, and clinical.This much the compiler of these reports gathered ill conversation with Hunter, % ho, unfor tunately, had not rel)a-red any manuscript of the thlree lectures lie had intended to givo.It had beeni hlis intention, as w-as hiis uisual custom, to speak without niotes, and apart from these conversations and the large ser ies of lantern slides aind cinematographic films, lie has left niothiing in tIme form of lectures.Yet the subject is so imiiportant in its scientific bearinigs, and the need for somiie exiplicit guide to surgeonis is so urgent, that the attemp't hlas been miade to do w-hat Huniter had intended to do, and to putblislh the reports.Time compiler has done niothiing miiore tliami select passages from Hunter's publishled and unpublished works and endeavour to give a connected and consistent accounit of his results.In addition to time thlee miiemoirs published in
Global Emergency Response
Authors: Joan Stephenson
Journal: JAMA (2003)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal