tbuckley/cabot-search huggingface dataset:
Blood Pressure Control in Hispanic Participants in the Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).
Authors: Karen L Margolis, Linda B Piller, Cora E Lewis, David C Goff, William C Cushman, Jackson T Wright, Pedro J Colon, Charles E Ford
Journal: Circulation (2001)

0021 In contrast to Black non-Hispanics (BNH), Hispanic Americans have a prevalence of hypertension that is similar to the White non-Hispanic (WNH)population. However, compared to BNH and WNH, hypertension awareness, treatment and control are much lower in Hispanics. ALLHAT is a double-blind randomized controlled trial in high-risk hypertensives age &gt;=55, comparing the effects of treatment with chlorthalidone, amlodipine, doxazosin and lisinopril (Step 1) on cardiovascular events. Open label treatment with atenolol, clonidine, reserpine (Step 2), and hydralazine (Step 3) may be added as necessary to achieve the goal of &lt;140 systolic (SBP) and &lt;90 diastolic (DBP). There are 32,398 participants with follow-up data at 24 months. Both White and Black Hispanics had similar SBP and BP control to WNH at 24 months of followup. Fewer Hispanics were taking maximal dose Step 1 or Step 2/3 medications. These results suggest that equal access to care can lead to equal BP control in White non-Hispanic and Hispanic Americans. Table 1.
JAMA Psychiatry
Authors: Phil Fontanarosa, Annette Flanagin, Brenda Gregoline, Tracy Frey, Shannon Sparenga, Nicole Balin, Miriam Cintron, Paul Ruich, Diane Cannon, Connie Manno, Fred Marshall, Laura Copyreaders, Catherine Adamczyk, Stephanie Alden, Jan Beckmeyer, Mary Clavey, Paula Coerver-Connolly, Roya Glitman, Laura Khatiblou, Donna King, Caroline Thordsen, Wanda Assistant, Larry Bryant, Monica Mungle, Elaine Williams, Lenette Gardner-Gullens, Fanny Brown, Paul Frank, Peter Kim, Rachell Lozano, Michaela Mark, Kathryn Muskovich, Saulsberry Gale, Michael Berkwits, Michelle Kurzynski, Eric Butkus, Will English, Craig Mccaff Rey, Reuben Rios, Ronna Henry, Joshua Bird, Karen Bucher, Samantha Welker, David Song, Deputy Livingston, Thomas Cole, Marla Hall, Deanna Willis, Yolanda Davis, Joseph Thornton, Preeti Malani, Deanna Bellandi, Jim Periodical, Thomas Easley, Brian Shields, Monica Smith, Jeff Ery, J Bonistalli, Kathy Russell, Mirna Monal, Stacey Mchugh, Marketing Thornbury, Tricia Classifi, Thalia Moss, Mike Harvey, Susan Henning, Saskia Bolore, Gretchen Linder, Brian Mccartney, David Baum, Rebecca Haas, Christine Hearne, Irma Lara, Ron Marketing, Paul Gee, Matt Herron, Elizabeth Solaro, Geoff Rey, Rick Bell, Lindsay Dawson, Michael Mcgraw, Romando Rossini, Stacy Staff, Millette Jackson-Bates, Karen Adams-Taylor, Karl Elvin, Jaye Mize, Sean O'donnell, Sue Managers, David Antos, Chris Borden, Debbie Camp, Lydia Cruz, Scott Curl, Diane Darnell, Colleen Kelly, Chris Meyer, Annemarie Neff, J Neff, Sean Ohlson, Phil O'leary, Bill Pedone, Susan Price, Denise Steinhauser, Production Services, Kim Boler, Rhonda Brown, Timothy Burke, Daniel Degroot, Jordynn Farrar, Euwanaha Joiner-Smith, Cindy Rendlen, Ellen Yoshihara, Circulation Services, Julie Burton, Dexter Golden, Erin Hinchcliff, Maria Nienhaus, Noemi Rivera, Geneine Van, Someren Composition, New Media, Gail Barrett, Regina Brownlee, Amanda Camino, Brenda Chandler-Grayer, Emily Dunn, Amy Evers, Teri Hutchison, Mary Kuranda, Joshua Lampinen, Nathan Mitre, Patricia Panek, La Son, Diggs Sledge, George Thomson Graphics, Joe Amft, Maria Duda, Fred Furtner, Carolyn Hall, Maria Kowalkowski, Proofreading Carol, Joy Farrell, Daniel James, Judith Literskis, Teresa Omiotek, Sam Wilder, James Madara, Bernard Hengesbaugh, Dan Blazer, North Carolina, David Braff, La Jolla, Naomi California, Stephen Breslau, Washington Dager, Atlanta Druss, Susan Georgia, New Essock, New York, Ellen York, John Hardy, James Harris, Maryland Shitij Kapur, Kenneth Kendler, Virginia Ronald, C Kessler, Kathleen Merikangas, Maryland Samples O'malley, Michael Owen, Fmed Sci, Judith Rapoport, Maryland Charles, F Reynolds, Myrna Weissman, Naomi Wray, Charles Zorumski, St Louis, Roy Grinker Sr, Daniel Freedman, Jack Barchas, Joseph Coyle, Jennifer Urbano Blackford, Dost Öngür, Ira Phillips, Helena Chmura Kraemer, Howard Bauchner
Journal: JAMA Psychiatry (2015)
Selective Carotid Angiography. A Preliminary Report
Journal: JAMA (1963)

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Book Review Asthma and Hay Fever in Theory and Practice . Part I. Hypersensitiveness, Anaphylaxis, Allergy. By Arthur F. Coca, M.D. Part II. Asthma. By Matthew Walzer, M.D. Part III. Hay Fever. By August A. Thommen, M.D. Published by Charles C. Thomas, Springfield, Ill., Baltimore, Md. 1931. Price $8.50.
Journal: New England Journal of Medicine (1931)
Manuali Hoepli Sieroterapia.
Journal: JAMA (1898)

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Parallel 3: HCV Virology, Pathogenesis, and Immunology
Authors: Akira Nishio, Tomohide Tatsumi, Takatoshi Nawa, Takahiro Suda, Atsuo Takigawa, Tadashi Kegasawa, Yoshiki Onishi, Seii- Chi Tawara, Teppei Yoshioka, Satoshi Aono, Minoru Shigekawa, Hayato Hikita, Ryotaro Sakamori, Naoki Hiramatsu, Tetsuo Take- Hara;
Journal: Hepatology (2015)
9 Rare diseases
Journal: Annals of the Rheumatic Diseases (2000)

PS) 0.8→0.3mg/kg/d for 4 months and then on alternate days, methotrexate 15 mg/m 2 and indometacin 2 mg/kg/d.At the time the pain occurred she was receiving indometacin, PS (20 mg/kg/d), and cyclosporin A (3 mg/kg/d).There was no previous history of trauma in the aVected limb.Her imaging work up showed the following: x rays of knees and femur-skip lesions in the right femur, one sclerotic in the middle shaft with heavy periosteal reaction and another one mainly lytic with destruction of the cortical bone and periosteal reaction.Magnetic resonance imaging showed skip lesions localised in the middle third of diaphysis and in the distal metaphysis of the femur.The lesions destroyed the cortical bone, infiltrated the bone marrow, and produced a periosteal reaction without extension to the soft tissues or in the epiphysis.These lesions were indicative of a possible bone solid tumour-that is, osteosarcoma or Ewing's sarcoma.However, a thallium scan was not indicative of malignancy.Her haematological and biochemical findings, including alkaline phosphate and lactate dehydrogenase, were also within normal limits.An open bone biopsy was then performed and ruled out the chance of malignancy; it showed aseptic necrotic lesions in the femur.The case is presented because of the unusual location and imaging appearance of the aseptic necrosis. Disablement by untreated systemic juvenile idiopathic arthritis
Clinical Lectures on Enlargement of the Prostate With a Description of the Author's Operation of Total Enucleation of the Organ.
Journal: JAMA (1921)

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Association News.
Journal: JAMA (1902)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Evaluation of monovalent influenza vaccine in a retirement community during the epidemic of 1965-66
Authors: W. H. Stuart
Journal: JAMA (1969)

Monovalent adjuvant and aqueous influenza vaccines were evaluated in a retirement community from 1964 to 1966. In the second year of investigation, an epidemic of A2 influenza provided opportunity to study the protective value of immunization. Vaccine efficacy was shown to be related to the pattern of vaccination. Individuals who had received single doses of A2 vaccine in both years of the study were considerably better protected than those who had received vaccine in only one of the years. The rate of febrile illnesses in the former group was more than 90% below that of vaccinated control. Those given one dose were only about half as well protected. Monovalent adjuvant A2 vaccine given more than a year before the outbreak appeared to protect as well as, if not slightly better than, monovalent aqueous vaccine administered several months before the epidemic.
The Pathology and Treatment or Diabetes Mellitus.
Journal: JAMA (1924)

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Inducible Apoptosis Eliminates Patient-Transferred T Cells
Journal: Cancer Discovery (2011)

that RAF inhibitors can promote tumor growth by inducing MAP kinase signaling in cells with wild-type BRAF or CRAF and mutant RAS.The authors therefore propose that keratinocytes that have acquired RAS mutations (perhaps due in part to toxic cellular effects of UV radiation) are primed for transformation upon exposure to RAF inhibitors.Although a massive parallel sequencing-based approach will be needed to identify the other genomic alterations driving cSCC and KA formation in response to RAF inhibitors, these findings suggest that coinhibition of RAS downstream effectors (e.g., MAP/ERK kinsase) may be effective in preventing secondary cancer formation in a subset of melanoma patients.≠
The logic of interests in neuroscience
Authors: Leslie Brothers
Journal: Behavioral and Brain Sciences (1999)

Logical problems inherent in claims that biological neuroscience can ultimately explain mind are not anomalous: They result from underlying social interests. Neuroscientists are currently making a successful bid to fill a vacuum of authority created by the demise of Freudian theory in popular culture. The conflations described in the Gold &amp; Stoljar target article are the result of alliances between certain apologist-philosophers, neuroscientists, and institutions, for the purpose of commanding authority and resources. Social analysis has a role to play in addressing logical issues in the philosophy of neuroscience.
An Analysis of Medical Ethics and Etiquette.
Journal: JAMA (1893)

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FILARIA SANGUINIS HOMINIS AT CHARLESTON.
Journal: JAMA (1890)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The extent of the anti-citrullinated protein antibody repertoire is associated with arthritis development in seropositive arthralgia patients
Authors: L A van de Stadt, A van der Horst, M de Koning, W H Bos, G J Wolbink, R J van de Stadt, G J M Pruijn, B A C Dijkmans, D van Schaardenburg, D Hamann
Journal: Annals of the Rheumatic Diseases (2010)

Purpose Anti-citrullinated protein antibodies (ACPA) are probably involved in the pathogenesis of rheumatoid arthritis.During the course of disease epitope spreading might occur.In this study, the ACPA repertoire of arthralgia patients and the association with arthritis development were studied.Methods 244 arthralgia patients positive for anti-cyclic citrullinated peptide antibodies (aCCP) and/or IgM rheumatoid factor, without clinical symptoms of arthritis were included.Arthritis was defi ned as the presence of one or more swollen joints at clinical examination during twice-yearly follow-up.Sera were tested at baseline for reactivity to fi ve citrullinated peptides derived from fi brinogen (three), vimentin (one) and α-enolase (one) and the fi ve corresponding arginine peptides in an ELISA.Results 65 patients (27%) developed arthritis in a median of two joints after a median follow-up of 10 (IQR: 4-18) months.Reactivity to each peptide was signifi cantly associated with arthritis development (p<0.01).The peptide reactivity pattern did not differ between patients who did or did not develop arthritis.Within aCCP positive patients, patients who recognised two or more additional citrullinated peptides developed arthritis more often (p=0.05).The number of recognised peptides was positively associated with the aCCP level (p<0.001).Cross-reactivity between different peptides was minimal. ConclusionThe ACPA repertoire in arthralgia patients can already be expanded.High aCCP levels are associated with a qualitatively broad ACPA response.Patients with a broader ACPA response have higher risk of developing arthritis.This indicates that epitope spreading occurs in arthralgia patients and might be initiated before onset of joint complaints.on August 9,
Comment
Authors: D. S. Tunstall Pedoe
Journal: British Journal of Sports Medicine (1989)

Sudden death in highly trained athletes during organized competitive exercise is very infrequent, considering the large number of participants" 2.Sudden death in marathon running has been de-scribed3 but few reports have tried to relate sudden death during vigorous exercises to age4'5.We report a previous healthy 56-year-old man who had a cardiac collapse Iduring the 'Wonderful Copenhagen Marathon' 1987.He was a highly trained athlete who had completed eleven previous marathon races and never been treated for cardiovascular disease.After 36 km of the race he suddenly collapsed with- out warning.Resuscitation was initiated at once and the race medical staff reached the patient after three minutes.Ventricular fibrillation was diagnosed and DC defibrillation was successful.On hospital admis- sion ten minutes later he was alert, cardiovascularly st- able and denied any chest pain prior to collapse.Coronary enzymes were slightly elevated (CKMB, LDH) and ECG was compatible with an inferior subendocardial infarction.Echocardiography was nor- mal.The patient was discharged uneventfully after
Trace Elements in Human Health and Disease. Vol. 1. Zinc and Copper and Vol. 2. Essential and Toxic Elements
Journal: Gut (1977)

This book reports on the papers and discussion at a symposium of which the date and site are unfortunately not men- tioned in the book. (On inquiry, the pub- lishers tell us that it was held at the Welsh National School of Medicine on 7, 8, and 9 July 1975 and that it was a Postgraduate Course in paediatric gastro- enterology organised by J. A. Dodge).It covers development of the gut in the fetus and young children; infancy and its problems; diarrhoea; abdominal pain, and constipation.It conveniently brings together much valuable scattered infor- mation, but the price seems high for a paperback.
Abdominal Ultrasound
Authors: Ann Maravilla
Journal: JAMA (1977)

<i>Abdominal Ultrasound</i>is a beautifully illustrated, well-organized approach to sonographic analysis of the abdomen. Its only fault is that it presents the material primarily using conventional B-scans. Gray-scale B-scans have now proved themselves superior in defining lesions, and the current emphasis on their use will probably make this book unappealing to most readers. The book emphasizes normal anatomy, basic approaches to scanning, and the many pitfalls in interpretation inherent in the method. Its description of sonopathology is excellent and well illustrated. Separate chapters are devoted to the liver, biliary system, pancreas, spleen, kidneys, retroperitoneum, great vessels, gastrointestinal tract, urinary bladder and prostate, female organs, and fluid collections. Many books on the abdomen do not include the female reproductive system. Holm presents a cursory description, but it is sufficient to provide a good introduction. The chapter on errors and pitfalls and the one on indications for ultrasonic scanning of the abdomen
Omitted Potential Conflict of Interest Disclosures
Authors: Amil Shah
Journal: JAMA Cardiology (2018)

Venkatesh Y. Anjan, MD; Howard C. Herrmann, MD; Philippe Pibarot, PhD; William J. Stewart, MD; Samir Kapadia, MD; E. Murat Tuzcu, MD; Vasilis Babaliaros, MD; Vinod H. Thourani, MD; Wilson Y. Szeto, MD; Joseph E. Bavaria, MD; Susheel Kodali, MD; Rebecca T. Hahn, MD; Mathew Williams, MD; D. Craig Miller, MD; Pamela S. Douglas, MD; Martin B. Leon, MD