tbuckley/cabot-search huggingface dataset:
PTH-073 Do gastroenterologists advise their susceptible patients appropriately about immunisation?
Authors: R Kia, M R Saleem, A Singhal, A I Thuraisingam
Journal: Gut (2010)

<h3>Introduction</h3> There is evidence-based guidance, including from the Department of Health, supporting vaccination of patients with susceptible gastroenterological conditions. The recent pandemic flu has also raised the profile of vaccination programmes for at-risk patients. Anecdotally, Gastroenterologists rarely advise vaccinations for these patients. <h3>Methods</h3> We aimed to assess current uptake of vaccination in at-risk Gastroenterology patients. We prospectively audited vaccination uptake in the preceding 12 months, against influenza and pneumococcal disease among 100 consecutive eligible gastroenterology patients on immunomodulators or with chronic liver disease (CLD) seen in clinics or wards. Hepatitis A and B vaccination uptake were also assessed in CLD patients. The underlying diagnoses, type of immunomodulators and Child-Pugh scores were recorded. Patients who received vaccinations were also asked who advised their vaccination. <h3>Results</h3> We identified 57 males and 43 females with a mean age of 51 (range 19–83). 52% were on immunomodulators (31 Azathioprine, 9 Infliximab, 1 Adalimumab, 1 6-Mercaptopurine, 10 Combination) while 48% had CLD. Indications for immunomodulators include Crohn9s disease (56%), UC (25%), autoimmune hepatitis (15%) and post-liver transplant (4%). Diagnoses for CLD patients include ALD (59%), HCV infection (13%), PBC (6%), NAFLD (4%), autoimmune hepatitis (4%), haemochromatosis (4%), HBV infection (2%) and mixed aetiologies (8%). Only 10% of patients had both influenza and pneumococcal vaccines, while 27% had influenza vaccination alone. Of the eligible CLD patients, only 2/46 (4%) patients had both HAV and HBV vaccinations while 1/46 (2%) had HBV vaccination only. Of the 38 patients who had at least one vaccination, 73% were advised to by their general practitioner, 11% by the gastroenterology team, 11% via self-referral and 5% via other secondary care teams. <h3>Conclusion</h3> Despite national guidance, only about one third of our susceptible gastroenterology patients are receiving all or some of the appropriate vaccinations. Of the patients receiving vaccination, most do not receive all the recommended vaccinations. This suggests a failure to disseminate guidance rather than a lack of patients9 willingness to receive them. Most patients receiving vaccination were advised by their GPs. Few patients were advised by the Gastroenterology department, despite Gastroenterologists initiating immunomodulators and caring for susceptible patients. A departmental guideline is being created to ensure recommendations to receive all appropriate vaccinations are made to patients and their GPs. These findings may be similar in many UK hospitals and our findings may be more widely applicable.
INTRODUCTORY ADDRESS.
Authors: EDMUND ANDREWS
Journal: JAMA (1895)

<h3>DO NOT LET YOUR LATIN SPOIL YOUR ENGLISH.</h3> You have all prepared yourselves with some knowledge of Latin and Greek to assist your medical studies. Many of you have received degrees from colleges and universities such as Bachelor of Arts, Bachelor of Sciences, Master of Arts, etc., given as honors for your hard study in these and other branches. Your knowledge of Latin and Greek will immensely facilitate your understanding and memory of technical terms, as well as promote your skill in writing prescriptions and will prove a valuable element in your mental culture. To this end and to this extent, you may well be glad of your knowledge of the classic languages. Connected with this knowledge, however, there is a peril besetting the development of your literary style. It is the danger of allowing Latin and Greek derivatives to crowd unnecessarily into your speech and writings, corrupting the purity
Contents
Authors: Cécile Delcourt, Mélanie Le Goff, Therese Von Hanno, Alireza Mirshahi, Anthony Khawaja, Virginie Verhoeven, Ruth Hogg, Eleftherios Anastosopoulos, Maria Cachulo, René Höhn, Christian Wolfram, Alain Bron, Stefania Miotto, Isabelle Carrière, Johanna Colijn, Gabriëlle Buitendijk, Jennifer Evans, Dorothea Nitsch, Panayiota Founti, Jennifer Yip, Norbert Pfeiffer, Catherine Creuzot-Garcher, Rufino Silva, Stefano Piermarocchi, Fotis Topouzis, Geir Bertelsen, Paul Foster, Astrid Fletcher, Caroline Klaver, Jean-François Korobelnik, Joseph Hull, Charles Czeisler, Steven Lockley, Thomas Berk, Matthew Schlenker, Xavier Campos-Möller, Austin Pereira, Ike Ahmed, Chi Hoang, Viet Vu, Motoko Kawashima, Masakazu Yamada, Kazuhisa Suwaki, Miki Uchino, Chika Shigeyasu, Yoshimune Hiratsuka, Norihiko Yokoi, Kazuo Tsubota
Journal: Ophthalmology (2018)
Enhanced liver fibrosis test and liver stiffness variation over time in a prospective cohort of primary sclerosing cholangitis patients
Authors: Guri Fossdal, Kristine Wiencke, Ida Bjørk, Lasse Giil, Trine Folseraas, Tom Hemming Karlsen, William Rosenberg, Mette Vesterhus
Journal: Journal of Hepatology (2020)
Abdominal Epilepsy
Authors: Matthew T. Moore
Journal: JAMA (1979)

<h3>To the Editor.—</h3> In their article "Ab dominal Epilepsy," Peppercorn et al (240:2450, 1978) state: "the disorder rarely has been reported in older adolescents and adults." By 1952 I had already reported 28 cases of abdominal epilepsy,<sup>1</sup>the majority of which were in adults aged 19 to 63 years, and quoted the literature wherein adults as well as children were involved<sup>1-3</sup>(124:561, 1944; 129:1233,1945). Since then I have seen many cases, mainly in adults. The majority of such cases in children and young adolescents gravitate to pediatricians; thus, the reports of Livingston<sup>4</sup>and others have, by now, primarily conditioned pediatricians to an awareness of the disorder. In devising the term "abdominal epilepsy," first in 1943 and 1944, it was my purpose to call attention to a syndrome of paroxysmal abdominal pain whose symptoms and etiology had not been adequately recognized as an aberrant form of epilepsy and
The Government Hospital for the Insane.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Massive bleeding
Authors: Augusto B. Federici
Journal: HemaSphere (2018)

Hematology and Transfusion Medicine, L. Sacco University Hospital, Department of Oncology and Hematology Oncology, University of Milan, Italy This is an open access Abstract Book distributed under the Attribution-NonCommercial-NoDerivs (CCBY-NC-ND), which allows third parties to download the abstracts and share them with others as long as they credit the author and the abstract book, but they cannot change the content in any way or use them commercially. http://creativecommons.org/licenses/by-nc-nd/4.0
Aerospace Medicine; The First 200 Years
Authors: Terra Ziporyn
Journal: JAMA (1986)

AMERICAN AEROSPACE MEDICINE went on record exactly 200 years ago, when a Massachusetts physician's account of his scientific observations during pioneering balloon flights was read before members of the Royal Society in Britain. Shortly thereafter, what has been called "the first book in the English language on aeronautics by an American" appeared under the title "A Narrative of the Two Aerial Voyages of Doctor Jeffries with Mons [sic] Blanchard; with Meteorological Observations and Remarks, by Doctor Jeffries, London, 1786." The author in both instances was John Jeffries, MD, who was born Feb 5, 1744, in Boston. He generally is credited with being "the first American to make a free flight in a balloon and the first balloonist to conduct scientific studies of the atmosphere" (<i>Aviat Space Environ Med</i>1984;55:993-999 and 1985;56:99-104). He did so during a Nov 30, 1784, flight from London to Kent and a Jan 7, 1785, crossing
MNGI-26. THE DISEASE BURDEN OF MENINGIOMA PATIENTS: LONG-TERM RESULTS ON WORK PRODUCTIVITY AND HEALTHCARE CONSUMPTION
Authors: Amir Zamanipoor Najafabadi, Pim van der Meer, Florien Boele, Rob Nabuurs, Johan Koekkoek, Frank Lagerwaard, Jaap Reijneveld, Wilco Peul, Martin Taphoorn, Martin Klein, Wouter van Furth, Linda Dirven, Saskia Peerdeman
Journal: Neuro-Oncology (2018)

BACKGROUNDMeningioma patients suffer from short- and long-term neurological sequelae and impaired health-related quality of life (HRQoL). However, it is unknown how these impairments affect patients work productivity and healthcare consumption on the long-term.
Phase II study of combination cisplatin, docetaxel and erlotinib in patients with metastatic/recurrent head and neck squamous cell carcinoma (HNSCC)
Authors: E. S. Kim, M. Kies, A. Sabichi, L. Ginsberg, B. Burke, C. Holsinger, L. Feng, M. T. Truong, B. Glisson, W. K. Hong
Journal: Journal of Clinical Oncology (2005)

5546 Background: Interrupting the epidermal growth factor receptor (EGFR) signaling pathway has shown promise in a variety of cancers and preclinical data has demonstrated possible synergy with platinums and taxanes. Treatment options for advanced or recurrent HNSCC are limited. A recent study of cisplatin and docetaxel showed a response rate of 40% and 9.6 month median survival. Erlotinib, an EGFR tyrosine kinase inhibitor, had a 4.3% response rate in HNSCC. Because of the possible synergy and efficacy, we proposed to study the combination of cisplatin, docetaxel and erlotinib in advanced HNSCC. Methods: Patients were required to have adequate performance status, measurable disease, no prior EGFR therapy, and may have received one regimen of induction, concomitant or adjuvant chemotherapy, but not for recurrent/metastatic disease. Sites of disease included squamous cell head and neck sites excluding nasopharynx and sinus. Treatment included docetaxel 75mg/m2 and cisplatin 75mg/m2, intravenously every 3 weeks and erlotinib 150 mg by mouth daily. Results: Nineteen patients have been enrolled thus far. Median age is 54 years (range 45–72). Median ECOG PS is 1 (range 0–2). Thus far, 16 patients are evaluable for response using RECIST criteria. Partial responses have been seen in 14 of 16 patients (confirmed and unconfirmed) including 3 patients who completely regressed in the head and neck region and 2 patients had stable disease. 3 patients have since progressed. One patient had grade 4 febrile neutropenia and 1 patient a grade 3 rash. Otherwise, no other significant grade 3 or 4 toxicities have been reported. The most common grade 1–2 toxicities were diarrhea, nausea, and rash. Conclusions: The combination of cisplatin, docetaxel and erlotinib is well tolerated and has very encouraging early activity in advanced HNSCC. Data collection for response rate, duration of response and survival is ongoing. Trial accrual continues up to 50 patients and biopsies are being collected for correlative markers including downstream EGFR pathway markers (p-akt, mek, k-ras). No significant financial relationships to disclose.
PRESIDENT'S ADDRESS.
Authors: T. L. McDERMOTT
Journal: JAMA (1895)

It is a gratifying duty that devolves upon me, to welcome you to these quarters and to inaugurate the opening of the Academy of Medicine. It has long been a matter of unfavorable comment that so prosperous a medical center as this, embracing in its circuit so many luminous votaries, who would add grace and lustre to any sphere, has so long been denied the pleasure and profit that must, of necessity, arise from more intimate communication among its most zealous devotees. Aside from the fact that such gatherings, not only foster the purest instincts of ethical fraternity but also refine and advance our calling, the mere existence of such an Academy proves the unselfish desire of its founders to strengthen the professional ties that bind us to a lofty purpose, the elevation of our guild and the widening of its beneficent power. What prince or potentate beloved of the
Transfusion into the Left Ventricle
Authors: William Congreve
Journal: JAMA (1967)

<h3>To the Editor:—</h3> An occasion may arise when open cardiac massage is necessary and possible, yet other trained personnel are not immediately available to start a transfusion or to cutdown on a suitable vessel. Rapid replacement of circulatory volume may be a sine qua non to maintain life. Such an event occurred in the emergency room when a 13-year-old boy was admitted with a stab wound of the left side of the chest. While a cutdown was being started, the boy's heart stopped. Work on the cutdown was stopped, and the chest was opened on the left side just below the nipple. The chest was full of blood and there was a hole in the pericardium. After opening the pericardium, the heart started to beat after one or two massages. It was possible to suture the three-quarter inch hole in the ventricular apex on the left side of the heart
Joggers may live longer..
Authors: N. M. Kaplan
Journal: JAMA (1984)

The universal admiration for athletic excellence, exemplified in the Olympics, caps an attitude about the value of physical exercise that is almost as pervasive. Unfortunately the evidence that physical exercise does more than make us feel better has been hard to come by. And for some, such as the anonymous author of the quote "Joggers don't live longer, it just seems like it," the benefits of physical exercise are not only unproved but unobtainable by most ordinary people. The article by Blair et al<sup>1</sup>in this issue ofThe Journalprovides some very suggestive evidence that physical fitness provides protection against the development of hypertension during the next one to 12 years. Those with low levels of physical fitness at the initial examination had a 1.52 greater relative risk for the development of hypertension than did those with higher levels of physical fitness, after appropriate adjustment for age, sex,
Species Differences in the Metabolism of Benzene
Authors: Rogene F. Henderson
Journal: Environmental Health Perspectives (1996)

The pathways of metabolism of benzene appear to be qualitatively similar in all species studied thus far.However, there are quantitative differences in the fraction of benzene metabolized by the different pathways.These species differences become important for risk assessments based on animal data.Mice have a greater overall capacity to metabolize benzene than rats or primates, based on mass balance studies conducted in vivo using radiolabled benzene.Mice and monkeys metabolize more of the benzene to-hydroquinone metabolites than do rats or chimpanzees, especially at low doses.Nonhuman primates metabolize less of the benzene to muconic acid than do rodents or humans.In all species studied, a greater proportion of benzene is converted to hydroquinone and ring-breakage metabolites at low doses than at high doses.This finding should be considered in attempting to extrapolate the toxicity of benzene observed at high doses to predicted toxicity at low doses.Because ring-breakage metabolites and hydroquinone have both been implicated in the toxicity of benzene, the higher formation of those metabolites in the mouse may partially explain why mice are more sensitive to benzene than are rats.Metabolism of benzene in humans, the species of interest, does not exactly mimic that of any animal species studied.More information on the urinary and blood metabolites of occupationally exposed people is required to determine the fractional conversion of benzene to putative toxic metabolites and the degree of variability present in human subjects.
Effects of Load and Duration of Tension on Pain Induced by Muscular Contraction
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Aerospace Medicine, St. Paul
Journal: JAMA (1969)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Obituaries
Journal: JAMA (1983)

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PURPURA FULMINANS DURING CONVALESCENCE FROM SCARLET FEVER
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
AFTER THE FIRE.
Journal: JAMA (1895)

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