tbuckley/cabot-search huggingface dataset:
A controlled trial of buprenorphine treatment for opioid dependence
Authors: R E Johnson, J H Jaffe, P J Fudala
Journal: JAMA (1992)

To assess the efficacy of buprenorphine for short-term maintenance/detoxification.A randomized, double-blind, parallel group study comparing buprenorphine, 8 mg/d, methadone, 60 mg/d, and methadone, 20 mg/d, in a 17-week maintenance phase followed by an 8-week detoxification phase.Outpatient facilities at the Addiction Research Center, Baltimore, Md.One hundred sixty-two volunteers seeking treatment for opioid dependence.In addition to the medication, counseling using a relapse prevention model was offered but not required.Retention time in treatment, urine samples negative for opioids, and failure to maintain abstinence.Throughout the maintenance phase, retention rates were significantly greater for buprenorphine (42%) than for methadone, 20 mg/d (20%, P less than .04); the percentage of urine samples negative for opioids was significantly greater for buprenorphine (53%, P less than .001) and methadone, 60 mg/d (44%, P less than .04), than for methadone, 20 mg/d (29%). Failure to maintain abstinence during the maintenance phase was significantly greater for methadone, 20 mg/d, than for buprenorphine (P less than .03). During the detoxification phase, no differences were observed between groups with respect to urine samples negative for opioids. For the entire 25 weeks, retention rates for buprenorphine (30%, P less than .01) and methadone, 60 mg/d (20%, P less than .05), were significantly greater than for methadone, 20 mg/d (6%). All treatments were well tolerated, with similar profiles of self-reported adverse effects. The percentages of patients who received counseling did not differ between groups.Buprenorphine was as effective as methadone, 60 mg/d, and both were superior to methadone, 20 mg/d, in reducing illicit opioid use and maintaining patients in treatment for 25 weeks.
Journal of Investigative Dermatology, Baltimore
Journal: JAMA (1969)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Diseases of the Veins
Authors: John Homans
Journal: New England Journal of Medicine (1946)

Anticoagulant Treatment The anticoagulants, represented by heparin and dicumarol, have been extensively used in many large clinics, particularly by way of postoperative prophylaxis against thrombosis and embolism. The most significant recent figures come from Swedish sources and from the Circulatory Division of the Mayo Clinic.As a background for the latest Swedish figures, the second report of Crafoord28 from Stockholm may be recalled. Heparin was given prophylactically in surgical cases. The earlier method of continuous intravenous drip had been abandoned. The drug was given routinely in four intravenous doses of something like 75 mg. three times during the day, and . . .
Inorganic Particles of Agricultural Origin
Authors: Kingsley Kay
Journal: Environmental Health Perspectives (1974)

Substantial quantities of mineral silicates are used as carriers for agricultural pest control agents. Most of this material is applied by air dissemination, either dry or as a droplet spray. Therefore, pulmonary and gastric deposition of the mineral carriers (and active agents) will occur among pesticide application personnel and some proportion of the general population in the vicinity of pest control operations—to the extent that particle size of the disseminated material is below the critical 5μm respirable diameter. Furthermore, ingestion of particulates deposited on food crops may be expected as well as mineral finding its way into drinking water supplies. It has been found that the silicates widely used in America can contain three forms of asbestos, anthophyllite, tremolite, and chrysolite. Of these, anthophyllite and chrysotile have been found associated with a neoplastic outcome after many years of exposure. It is therefore proposed that comprehensive mineralogical investigation of pesticide carriers is warranted, including epidemiological and clinical study of formulation and application personnel as well as exposed nonoccupational populations.
Customized Probability Models for Severe Sepsis: Correction and Clarification-Reply
Authors: Stanley Lemeshow
Journal: JAMA (1995)

<h3>In Reply</h3> .—We thank Dr Jeffs for detecting the typographical errors in the equations for customizing SAPS II and MPM II<sub>24</sub>. We regret that we did not detect these in the page proofs. Dr Rubenfeld raises a number of concerns regarding the use of severity systems such as MPM II and SAPS II in an ICU environment. All severity systems for ICU patients were developed and validated on databases that included a wide range of patient diagnoses and conditions. However, no statistical model can be guaranteed to perform well for groups of patients not included in the original study population or, for that matter, exclusively for specific subgroups of patients (eg, patients with sepsis or cancer). Good model performance cannot be taken for granted. If ICU care is either much better or much worse than what a statistical model would lead us to expect, this could be due to
FAMILY PRACTICE PROGRAM
Journal: JAMA (1960)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Carcinogenicity Testing of Phthalate Esters and Related Compounds by the National Toxicology Program and the National Cancer Institute
Authors: W. M. Kluwe, E. E. McConnell, J. E. Huff, J. K. Haseman, J. F. Douglas, W. V. Hartwell
Journal: Environmental Health Perspectives (1982)

Five phthalate ester and related compounds (phthalic anhydride, phthalamide, di(2-ethylhexyl) phthalate, di(2-ethylhexyl) adipate and butyl benzyl phthalate) have been tested for carcinogenic effects in standard lifetime rodent feeding studies. Groups of 50 male and female rats and mice were fed diets containing various concentrations of the test chemicals for 102-106 consecutive weeks. The dietary concentrations were estimated to be maximally tolerated doses and half maximally tolerated doses. All animals that died during the study and all survivors at the end of two years were examined grossly and microscopically for the presence of tumors. The incidences of animals with tumors at a specific anatomic site in the treated groups and the controls were compared statistically. Neither phthalamide nor phthalic anhydride increased tumor incidences in rats or mice. Di(2-ethylhexyl) phthalate increased the incidences of liver tumors in rats and mice of both sexes, while di(2-ethylhexyl) adipate caused liver tumors in male and female mice, only. Butyl benzyl phthalate did not cause tumors in male or female mice, but the incidence of myelomonocytic leukemia in butyl benzyl phthalate-treated female rats was significantly greater than that in the controls. Chemically induced early deaths in the butyl benzyl phthalate-treated male rats precluded an evaluation of carcinogenic potential in this sex. Under the conditions of these tests, di(2-ethylhexyl) adipate was considered to be carcinogenic in both rats and mice and di(2-ethylhexyl) adipate was considered to be carcinogenic in mice. The evidence for carcinogenic effects of butyl benzyl phthalate in female rats was judged to be equivocal because of the variable nature of the incidence of myelomonocytic leukemia in Fischer 344 rats. Phthalamide and phthalic anhydride did not exhibit carcinogenic effects in these studies.
Reply to Eliezer M. Van Allen, Levi A. Garraway and Jonathan E. Rosenberg's Letter to the Editor re: Floris H. Groenendijk, Jeroen de Jong, Elisabeth E. Fransen van de Putte, et al. ERBB2 Mutations Characterize a Subgroup of Muscle-invasive Bladder Cancers with Excellent Response to Neoadjuvant Chemotherapy. Eur Urol. In press. http://dx.doi.org/10.1016/j.eururo.2015.01.014
Authors: Floris H. Groenendijk, Elisabeth E. Fransen van de Putte, Bas W.G. van Rhijn, René Bernards, Michiel S. van der Heijden
Journal: European Urology (2015)
关于向接触性过敏患者提供的附加信息的研究
Journal: British Journal of Dermatology (2021)

接触性皮炎是皮肤与环境中的特定物质接触而引起的一种湿疹。它可能会导致手部湿疹等慢性皮肤病, 因此识别过敏反应并了解过敏原可能出现的位置至关重要。否则, 湿疹将变得难以治疗, 并可能影响患者的日常生活和工作能力。超过四分之一的欧洲人被证明患有某种接触性过敏症。
Second Central Nervous System Prophylaxis in Children With Acute Lymphoblastic Leukemia Who Relapse After Elective Cessation of Therapy
Authors: Gaston Rivera, Stephen L. George, W. Paul Bowman, David Kalwinsky, Judith Ochs, Gary V. Dahl, H. Omar Hustu, Joseph V. Simone
Journal: Journal of Clinical Oncology (1983)

In the August issue of the Journal, the article by Rivera et al (1:471–476, 1983) contains an error. In Table 2 under the treatment for Phase II, the second complete line should read MTX† 10 mg/m 2 + ara-C 50 mg/m 2 IT every 6 wk.
Commission On Medical Care Costs
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Emergency medical services: factors associated with poor survival
Authors: W. H. Bickell
Journal: JAMA (1994)

<h3>In Reply.</h3> —Dr Bickell's conjecture that specially trained physician directors of EMS systems positively influence out-of-hospital cardiac arrest survival rates has not been supported by the New York City experience. New York City was the first municipality in the United States to employ a full-time specially trained physician director of EMS and had continued to do so since 1981. Despite the influence of these individuals, New York City EMS was unable to achieve the impressive survival rates of the smaller systems cited by Bickell. At the time of our study, New York City EMS coordinated the deployment of 583 ambulance tours daily, staffed by 650 paramedics and 1700 emergency medical technician/defibrillators who respond to 1 million calls annually. The impact of any one person on such a vast system is likely to be substantially less than in the Houston experience. During the period of our study, in Houston there were
SCARLET FEVER.
Authors: WILLIAM L. BAUM
Journal: JAMA (1903)

During the years 1896 to 1903 the following cases of scarlet fever were under my observation at the Cook County Hospital: Number of cases, 628; males, 307; females, 321; deaths, 44. <h3>Complications.</h3> —Suppurative otitis, 11; nephritis, 47; pneumonia, 19; arthritis, 2. <h3>Mixed Infections.</h3> —Number of cases, 142; deaths, 17; diphtheria, 96; measles, 29; diphtheria and measles, 1; varicella, 13; parotitis, 3. It will be seen from the above table that the mortality was a little over 7.07 per cent. of all the cases treated. In the mixed infections the mortality was 11.9 per cent. It will be noted that among the complications, suppurative otitis media occurred eleven times, or in 1.7+ per cent. of all cases. In about 35 per cent. of the cases there was pain in the ear. The mild or catarrhal form of otitis media, according to Bader and
Incorrect Illustration
Journal: JAMA (1982)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
YELLOW FEVER ON THE ISTHMUS OF PANAMA UNDER THE FRENCH REGIME.
Journal: JAMA (1907)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Incorrect Arrows
Journal: JAMA (1990)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
ECDC publishes the annual epidemiological report 2012
Authors: None Eurosurveillance editorial team
Journal: Eurosurveillance (2013)

Preview this article: ECDC publishes the annual epidemiological report 2012, Page 1 of 1 < Previous page | Next page > /docserver/preview/fulltext/eurosurveillance/18/10/art20418-en-1.gif
Medical Education, Registration and Hospital Service
Journal: JAMA (1926)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
COVER—1960 DESIGN
Journal: JAMA (1960)

The façade of this issue ofThe Journalhas been selected among several suggestions that were scrutinized with a critical eye in recent months. For many years the cover was a one-color product, and the table of contents shared space with advertising. The introduction of a smattering of red and the increase in the Editorial-Advertising ratio occurred several years ago. Since early Spring the tempo of change has been augmented significantly. The omission of advertising on the April 23rd cover ofThe Journalwas the initial presentation to the medical profession of the philosophy of the current regimen for Improvement of the Scientific Publications of the A. M. A. It is reassuring to recount that this phase brought forth no hurricane of protestations. The comments sent on to this office were favorable. As the weeks went along, minor modifications here and little changes there were introduced slyly. More "white space"
Sudden Death in Young Athletes.
Authors: Thomas N. James
Journal: Annals of Internal Medicine (1967)

s1 May 1967Sudden Death in Young Athletes.Thomas N. James, M.D., F.A.C.P., Peter Froggatt, M.D., Thomas K. Marshall, M.D.Thomas N. James, M.D., F.A.C.P.Search for more papers by this author, Peter Froggatt, M.D.Search for more papers by this author, Thomas K. Marshall, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-66-5-1038_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSudden unexpected death of a young athlete is not an unfamiliar event, but, as part of the uniquely poignant tragedy it represents, there are often few medical facts to report. In such cases there is a limited number of possible mechanisms, of which a sudden cardiac arrhythmia is one. For this reason we recently examined the cardiac conduction system from two young athletes who died suddenly and in whom the routine necropsy provided no explanation. Patient A. C. was 15 years old and died during a team wrestling match. Patient J. M. was 16 years old and died while playing... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: Thomas N. James, M.D., F.A.C.P.; Peter Froggatt, M.D.; Thomas K. Marshall, M.D.Affiliations: Detroit, Michigan, Belfast, PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 May 1967Volume 66, Issue 5Page: 1038-1038KeywordsArrhythmia ePublished: 1 December 2008 Issue Published: 1 May 1967 PDF downloadLoading ...
TRANSILLUMINATION OF BREASTS
Journal: JAMA (1929)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal