tbuckley/cabot-search huggingface dataset:
VENEREAL DISEASE IN FICTION.
Journal: JAMA (1898)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
An American approach to health system reform
Authors: J. Holahan
Journal: JAMA (1991)

THE MAJOR problems in the United States' health care system today are the large number of uninsured Americans, the high and rising costs of the system, and the system's administrative complexity. With over 32 million Americans lacking health insurance at any time and 63 million Americans lacking health insurance at some point during a recent 28-month period, the problem of being uninsured is faced by a large percentage of the population.<sup>1-5</sup>Despite this lack of coverage, the United States spends more on health care, per capita and as a percentage of gross national product (GNP), than any other country. In addition, we also have one of the highest rates of increase—over 4% per year after adjusting for inflation.<sup>6,7</sup>Finally, it is estimated that the annual administrative expenses borne by insurance companies, physicians, hospitals, and other providers are about $80 billion, or 1.5% of GNP.<sup>8</sup>This does not
UREMIC PERICARDITIS.
Journal: JAMA (1895)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
DIPHTHERIA ANTITOXIN IN THE TREATMENT OF GOITER.
Journal: JAMA (2005)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Editor’s Choice
Authors: John Ingram
Journal: British Journal of Dermatology (2021)

Linked Article: Visconti et al. Br J Dermatol 2021; 184:https://doi.org/10.1111/bjd.19807 Linked Article: Thomas et al. Br J Dermatol 2021; 184:https://doi.org/10.1111/bjd.19592 © Cardiff & Vale University Health Board Linked Article: Caley et al. Br J Dermatol 2021; 184:https://doi.org/10.1111/bjd.19471 The role of the basement membrane in poorly differentiated cutaneous squamous cell carcinoma (cSCC) is not well understood. Analysis of cSCC tumours and cell lines using antibodies specific to laminin chains α3, β3 and γ2 identified a link between poorly differentiated cSCC and reduced expression of the laminin α3 subunit, but not the β3 and γ2 subunits. Knockdown of laminin α3 increased tumour invasion both in vitro and in vivo, and only the loss of laminin α3 correlated with increased tumour-associated macrophages both in xenografted tumours and in patients’ tumour samples. Inhibition of ROCK (rho-associated protein kinase) but not Rac1 significantly reduced the invasive potential of laminin α3 knockdown cells. These data provide evidence that loss of the laminin α3 chain in cSCC has effects on both the epithelial and immune components of cSCC, resulting in an aggressive tumour microenvironment. So laminin α3 expression by cSCC may have prognostic value, and there is potential for targeting ROCK activity in cSCCs lacking laminin α3 to block tumour invasion. Linked Article: Goldfarb et al. Br J Dermatol 2021; 184:https://doi.org/10.1111/bjd.19565 Lesion counts to quantify hidradenitis suppurativa (HS) severity in the physical signs domain are fraught with difficulty. Distinguishing abscesses from nodules, identifying skin tunnels and coping with lesions that have coalesced into inflammatory plaques are just some of the issues. HASI-R shifts away from individual lesion counts and, at each of 10 skin sites, assesses body surface area involvement, and the extent of skin tunnels, inflammatory induration, open skin surface and inflammatory colour change. To conduct this study on a snowy weekend in Hershey, Pennsylvania, I joined 19 other raters and 15 patients. Each rater independently assessed each patient using Hurley staging, modified and original Sartorius score, inflammatory lesion count, International Hidradenitis Suppurativa Severity Score System, and HASI-R. Inter-rater reliability for HASI-R was moderate, while it was poor for all the other instruments. HASI-R had the highest intrarater reliability and good construct validity. So, encouraging results, and the next steps include use of HASI-R in prospective trials to assess responsiveness to change and minimal clinically important difference.
Riboflavin Content of Livers in Experimental Burns
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
AMBROISE PARÉ
Journal: JAMA (1961)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Eyes after renal transplantation.
Journal: BMJ (1972)

Eyes after Renal TransplantationImmunosuppressive treatment is required after renal transplantation to prevent rejection of the graft.The drugs most commonly used for this are corticosteroids (predni- sone) and azathioprine, both of which can initiate or pre- dispose to ocular complications.Those described indude cataract, glaucoma, and retinitis due to cytomegalovirus infection.Opacities lying under the capsule at the posterior pole of the lens (posterior subcapsular cataract) were described in 10 out of 26 patients who had undergone renal transplant- ation.'They were discovered between 8 and 28 months after the operation, and there was no significant difference between the amount of immunosuppressive treatment given to the patients who developed the cataract and those who did not.But this week in the B.M.Y. (page 133) Mr. R. Porter and In later lesions the retinal architecture was disorganized and in still older lesions it was atrophic.Cytomegalovirus bodies were also present in the vascular endothelium, caus- ing occlusion of the vessels, and this was thought to be the route of the ocular infection.Dr. Porter and his co-workers describe two similar cases in their series of 39 patients, one 0 BRISH MEDICAL
LORD KELVIN.
Journal: JAMA (2007)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Dr Beeson
Journal: JAMA (2002)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Infectious Diseases
Authors: Laura L. Fisher
Journal: JAMA (1991)

The new decade has already witnessed significant developments in the subspecialty of infectious diseases. The acquired immunodeficiency syndrome (AIDS) remains the focus of worldwide epidemiologic, basic science, and clinical research. Zidovudine is the only therapy for the human immunodeficiency virus (HIV) approved by the Food and Drug Administration, although other promising antiretroviral drugs are being evaluated in clinical trials.<sup>1,2</sup> The list of indications for zidovudine treatment has been extended to include asymptomatic persons infected with HIV with fewer than 500 CD4 cells per cubic millimeter of blood. Other studies have attempted to determine the appropriate dosage for zidovudine, ie, that which maximizes therapeutic benefit while minimizing accompanying bone marrow toxic effects.<sup>3</sup>Based on recent AIDS Clinical Trials Group study findings, many clinicians have lowered the maintenance dosage regimen to 500 or 600 mg of zidovudine daily. No recommendations have been made for asymptomatic infected individuals with more than
Menarche and puberty in daughters of amenorrheic women
Authors: Z. Ben-Rafael
Journal: JAMA (1983)

Twenty-six daughters born to amenorrheic women after gonadotropininduced ovulation were studied at 10 to 16 years of age. The aim of the study was to assess whether the mothers' condition, namely, amenorrhea and infertility followed by the pharmacologic induction of ovulation, had any effect on their female offspring in terms of endocrine disorders at puberty. The daughters were found to have normal onset of puberty as well as normal physical and mental development. The mean age at menarche, body weight, and height were similar to those of the general female population in Israel. A functioning hypothalamic-pituitary-ovarian axis was evidenced by the appearance of menarche followed by regular cycles. These data form a reassuring sample for the clinicians, the treated mothers, and their offspring. (<i>JAMA</i>1983;250:3202-3204)
Parenthood by proxy
Authors: B. D. Hirsh
Journal: JAMA (1983)

AS THE use of contraceptives and incidence of abortion increase and unwed motherhood becomes socially acceptable, fewer babies will be available for adoption, and more childless couples and single people who want to be parents will seek the help of physicians. Although human artificial insemination has been in common use for more than 30 years, it is now receiving new public attention. Much publicity has been given to an arrangement described as "surrogate motherhood," involving the artificial insemination of a woman who agrees to give the child thus conceived for adoption to the husband providing the semen and his infertile wife. Reliable statistics are unavailable, but an estimated 200,000 persons in the United States were conceived by artificial insemination, and an estimated 8,000 women become pregnant each year by this means through services provided by approximately 500 physicians. The courts and legislatures have barely begun to confront even the most
Cerebral protection during carotid endarterectomy
Authors: J. E. Thompson
Journal: JAMA (1967)

Carotid endarterectomy has assumed an increasingly important role in the definitive management of patients with cerebrovascular insufficiency syndromes whose lesions are located in the extracranial vasculature. With proper selection of cases and careful attention to details of intraoperative management, endarterectomy can be performed with low morbidity and with operative mortality approaching 1%. Since no unnecessary risks should be taken in these patients, especially those with transient cerebral ischemic attacks and asymptomatic carotid bruits, some method of monitoring the adequacy of cerebral blood flow or a reliable means of cerebral protection during endarterectomy must be employed if strokes are to be prevented and aggravation of neurological deficits is to be avoided. Elsewhere in this issue (p 1023) White and associates report on the anesthetic management for carotid artery surgery. Their regimen includes hypercapnia, general anesthesia with halothane, spontaneous respiration, maintenance of each patient's normal blood pressure using phenylephrine if necessary, and
Acute Gouty Arthritis
Authors: David J. Nashel
Journal: JAMA (1982)

The initial treatment of acute gout is normally accomplished with the use of oral colchicine or one of the nonsteroidal anti-inflammatory drugs. However, in the setting of chronic alcoholism, the use of these agents may pose a significant risk to the patient. Prior to the use of antigout medications, the alcoholic patient should be assessed for the presence of gastrointestinal disease, anemia, and hepatic or renal dysfunction. The safest treatment in an alcoholic is intravenous colchicine or only analgesics. (<i>JAMA</i>1982;247:58-59)
Efficacy and safety of TMC125 (etravirine) in treatment-experienced HIV-1-infected patients in DUET-2: 24-week results from a randomised, double-blind, placebo-controlled trial
Authors: Adriano Lazzarin, Thomas Campbell, Bonaventura Clotet, Margaret Johnson, Christine Katlama, Arend Moll, William Towner, Benoit Trottier, Monika Peeters, Johan Vingerhoets, Goedele de Smedt, Benny Baeten, Greet Beets, Rekha Sinha, Brian Woodfall
Journal: The Lancet (2007)
Rochalimaea Infections
Authors: Jordan W. Tappero
Journal: Annals of Internal Medicine (1993)

Letters15 September 1993Rochalimaea InfectionsJordan W. Tappero, MD and Jane E. Koehler, MDJordan W. Tappero, MDSearch for more papers by this author and Jane E. Koehler, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-119-6-199309150-00022 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:We read with interest the concise editorial by Drs. Tompkins and Steigbigel [1] accompanying our article [2] describing the only immunocompetent patients reported in the literature with angiomatosis in the absence of human immunodeficiency virus infection or drug-induced immune suppression. Stating that bacillary angiomatosis in immunocompetent adults had been previously reported, the authors incorrectly cited three articles describing patients who had fever and bacteremia caused by Rochalimaea species but did not have the vascular lesions of either bacillary angiomatosis or parenchymal bacillary peliosis [3-5]. The error is frequently made and could lead to further confusion. The distinction ...References1. Tompkins DC, Steigbigel RT. Rochalimaea's role in cat scratch disease and bacillary angiomatosis. Ann Intern Med. 1993; 118:388-90. Google Scholar2. Tappero JW, Koehler JE, Berger TG, Cockerell CJ, Lee TH, Busch MP, et al. Bacillary angiomatosis and bacillary splenitis in immunocompetent adults. Ann Intern Med. 1993; 118:363-5. Google Scholar3. Slater LN, Welch DF, Hensel D, Coody DW. A newly recognized fastidious gram-negative pathogen as a cause of fever and bacteremia. N Engl J Med. 1990; 323:1587-93. Google Scholar4. Welch DF, Pickett DA, Slater LN, Steigerwalt AG, Brenner DJ. Rochalimaea henselae, sp. nov., a cause of septicemia, bacillary angiomatosis, and parenchymal bacillary peliosis. J Clin Microbiol. 1992; 30:275-80. Google Scholar5. Lucey D, Dolan MJ, Moss CW, Garcia M, Hollis DG, Wegner S, et al. Relapsing illness due to Rochalimaea henselae in immunocompetent hosts: implications for therapy and new epidemiological associations. Clin Infect Dis. 1992; 14:683-8. Google Scholar Author, Article, and Disclosure InformationAuthors: Jordan W. Tappero, MD; Jane E. Koehler, MD PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byBartonella Infections in HIV-infected IndividualsNucleic Acid-Based Discovery Techniques for Potential Xenozoonotic Pathogens 15 September 1993Volume 119, Issue 6Page: 535-536KeywordsAngiomatosisBacteremiaBartonellaEndocarditisFeversImmune suppressionInfectious diseasesLesionsMolecular epidemiologyPeliosis hepatis ePublished: 15 August 2000 Issue Published: 15 September 1993 Copyright & PermissionsCopyright © 1993 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Randomized Trial of Observation Versus Adjuvant Therapy With Cyclophosphamide, Fluorouracil, Prednisone With or Without Tamoxifen Following Mastectomy in Postmenopausal Women With Node-Positive Breast Cancer
Authors: James N. Ingle, Lloyd K. Everson, H. Sam Wieand, J. Kirk Martin, Henry J. Votava, Lester E. Wold, James E. Krook, Stephen A. Cullinan, J. Kevin Paulsen, Donald I. Twito, David L. Ahmann, John F. Foley, Stephanie J. Green
Journal: Journal of Clinical Oncology (1989)

In Table 4 of the manuscript by Ingle et al published in the September issue (J Clin Oncol 6:1388–1396, 1988) an error was made in the dosage of tamoxifen. The planned dose should have read 140 mg/wk; the mean dose, 125 mg/wk; and the median dose, 140 mg/wk.
Weight Reduction
Authors: James C. M. Chan
Journal: JAMA (1981)

Three patients with exogenous obesity were studied while fed a 400-kcal constant metabolic diet, provided as a single daily meal served at consecutive ten-day periods, starting with either the "breakfast" protocol at 8 AM or the "dinner" protocol at 5 PM. Both patients 1 and 2 had notably greater weight loss with the breakfast protocol than with the dinner. However, in patient 3 this difference was not demonstrated. Urine samples, collected at four-hour intervals throughout the studies and analyzed for sodium, potassium, calcium, phosphorus, 17-hydroxycorticosteroids, and aldosterone secretions, showed differences in excretion of minerals and hormones with the timing of meals. The data tentatively show an achievement of greater weight loss when the isocaloric diet is given at 8 AM. (<i>JAMA</i>1981;245:371-373)