tbuckley/cabot-search huggingface dataset:
Races, Nations and Jews
Journal: JAMA (1934)

In this book Dr. Tenenbaum treats a difficult social problem in the same way he would treat an obscure medical disease. In the first part of the book he discusses quite fully the underlying anthropologic and sociological factors that are etiologically related to antisemitism, which he regards as a serious social disease, from time to time reaching pandemic proportions. He reviews existing knowledge of the development of races and proves that there are no pure races. The Aryan race and the Nordic race have no sound basis in history of man's development; he regards them as entirely mythical, created by certain peoples to claim for themselves a superiority that is not based on scientific facts. Nations, too, cannot be defined by either language or territorial boundaries but are largely a state of mind. According to this point of view, he regards the Jews without a language and without a well
Heberden Society: Kennedy Institute, London, February, 1969
Authors: R Grahame, P Beighton, M Carter, V James, St Mary'
Journal: Annals of the Rheumatic Diseases (1969)

Discussion.-DR.MCCONKEY (Birmingham): Is the quantity of collagen normal or is it related to skin volume?DR.GRAHAME: It is related to skin volume.DR.MCCONKEY: What are the microscopic abnormalities?DR.GRAHAME: There are gross abnormalities in weave and architecture as seen by light microscopy although the electron microscopic appearances are normal.
AlphaVbeta6 inhibitor stabilizing the bent closed integrin conformation is effective in primary sclerosis cholangitis mouse model
Authors: Min Lu, Richard Chen, Bryce Harrison, Monica S. Montesinos, Lukasz Stawski, Vinod Yadav, Andrew Sullivan, Lia Luus, Patrycja Nowakowski, Laura Cappellucci, Sung Jo, Albert Lin, Qi Qiao, Eugene Nebelitsky, Meghan Monroy, Terence Moy, Dan Cui, Adrian Ray, Blaise Lippa, Alex Lugovskoy, Liangsu Wang, Bruce Rogers
Journal: Journal of Hepatology (2020)
Doctors, physiotherapists, and placebo pharmacology
Authors: S Bourne
Journal: BMJ (1979)

the fact that death is usually due to acute arrhythmia rather than pump failure points to (fresh) ischaemia as the cause.Lowering of blood pressure may be the actual mechanism responsible for initiating this.However, in- creased blood viscosity and platelet adhesive- ness could well raise the threshold of blood pressure which is operative.
Department of Error
Authors: Carsten Dittmayer, Jenny Meinhardt, Helena Radbruch, Josefine Radke, Barbara Heppner, Frank Heppner, Werner Stenzel, Gudrun Holland, Michael Laue
Journal: The Lancet (2020)

SARS-CoV-2.We only discussed two in our Correspondence 1 as examples to precisely address our concerns.The extent of misinterpretations or insufficiently founded interpretations of putative coronavirus particles was recently shown in a detailed review. 5 Similarly, we believe that electron micrographs that were published during the SARS pandemic in the early 2000s require further discussion.We agree with Dolhnikoff and colleagues that some concerns could be directly addressed to the authors.However, disputable publications spread very quickly, which can flaw the basis for a precise ultrastructural characterisation of SARS-CoV-2; thus, we are convinced that this crucial discussion required publication.
A Text-Book of Medicine
Journal: JAMA (1952)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Oral bioavailability of chromium from a specific site.
Authors: C M Witmer, R Harris, S I Shupack
Journal: Environmental Health Perspectives (1991)

Analysis of soil from a specific site in New Jersey indicated a low level of sodium and chromium present as a calcium compound. Chromium was then administered orally to young, mature male rats at a level of 240 micrograms/kg for 14 days as chromium-contaminated soil, as CaCrO4, and as an equimolar mixture of the soil and calcium salts for 14 days. The rats were sacrificed 24 hr after the last dosing, and tissues were taken immediately for chromium analysis. Blood, muscle, and liver contained the highest levels of chromium in these animals, although kidney contained the highest concentration per gram of tissue. The total amount of chromium in the tissues was less than 2% of the administered chromium. In a study of the excretion of chromium, the animals were dosed orally for 8 days (with CaCrO4 or contaminated soil, each at the level of 240 mumole Cr/kg), and the chromium in feces and urine was determined on days 1, 2, 7, and 8. After cessation of dosing for 27 days, the same rats were dosed for 2 days at the same level, and chromium in urine and feces was determined for the 2 days. The animals administered the chromium in soil had higher levels of chromium in both urine and feces on all days compared to the group fed the CaCrO4. The total recovery of chromium in any of the 2-day periods was less than 50% of the chromium administered during that period.
Percutaneous transluminal coronary angioplasty in New York State
Authors: J. A. Chiota
Journal: JAMA (1993)

<h3>To the Editor.</h3> —Recently, two<i>JAMA</i>articles detailed the practice of percutaneous transluminal coronary angioplasty (PTCA) in New York State for the years 1990 (Hilborne et al<sup>1</sup>) and 1991 (Hannan et al<sup>2</sup>). While Hilborne et al examined 1306 PTCAs at random, Hannan et al reviewed all 5827 procedures the following year. Hilborne et al followed procedural mortality, but in 1991, Hannan et al changed that end point to inhospital mortality. Such changes have made it difficult to detect trends in PTCA patterns in New York State from 1990 through 1991; however, analysis is still possible, and some conclusions prove to be disturbing. Most statistics (overall success rate, percentage of men, number of single-vessel PTCAs, postprocedure myocardial infarctions, and acute vessel occlusions) remained virtually unchanged from 1990 to 1991, while others varied only slightly (rate of emergency bypass and the percentage of patients aged 65 years and older). Mortality
Lessons Learned?
Authors: Patrick Yachimski
Journal: Annals of Internal Medicine (2018)

On Being a Doctor15 May 2018Lessons Learned?Patrick Yachimski, MD, MPHPatrick Yachimski, MD, MPHVanderbilt University Medical Center, Nashville, Tennessee (P.Y.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/M18-0204 Audio Reading - “Lessons Learned?” Audio. Michael A. LaCombe, MD, Annals Associate Editor, reads "Lessons Learned?," by P. Yachimski. Your browser does not support the audio element. Audio player progress bar Step backward in current audio track Play current audio trackPause current audio track Step forward in current audio track Mute current audio trackUnmute current audio track 00:00/ SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail She was a young wife and mother with widely metastatic breast cancer and carcinomatous meningitis. Acute lung injury developed after chemotherapy. This had prompted mechanical ventilation and admission to the ICU.My role as senior medical resident was to convey the ICU team's stark assessment and recommendations: She has incurable, terminal disease. This is hopeless. Get them to withdraw care. I sat at one head of the conference room table, the oncologist at the other head. The patient's husband and many extended family members flanked us on either side, overflowing the seats at the table and filling a second row ... Author, Article, and Disclosure InformationAffiliations: Vanderbilt University Medical Center, Nashville, Tennessee (P.Y.)Corresponding Author: Patrick Yachimski, MD, MPH, Associate Professor of Medicine, Director of Pancreatobiliary Endoscopy, Vanderbilt University Medical Center, Nashville, TN 37232-5280; e-mail, patrick.[email protected]lt.edu. PreviousarticleNextarticle Advertisement Audio Reading - “Lessons Learned?” Audio. Michael A. LaCombe, MD, Annals Associate Editor, reads "Lessons Learned?," by P. Yachimski. Your browser does not support the audio element. Audio player progress bar Step backward in current audio track Play current audio trackPause current audio track Step forward in current audio track Mute current audio trackUnmute current audio track 00:00/ FiguresReferencesRelatedDetails Metrics 15 May 2018Volume 168, Issue 10Page: 745KeywordsBiopsyBreast cancerCancer treatmentChemotherapyEndoscopyGratitudeIntensive care unitsMemoryVentilatorsVision ePublished: 15 May 2018 Issue Published: 15 May 2018 Copyright & PermissionsCopyright © 2018 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
DOG LIVER OIL.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Allied Health Education
Journal: JAMA (1978)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
MEDICAL TEACHING AND THE PRIVATE PATIENT
Journal: JAMA (1967)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Beauty Parlor Stroke: When a Beautician Becomes a Physician
Authors: Gary B. Beringer
Journal: JAMA (1993)

<h3>To the Editor.</h3> —Dr Weintraub's<sup>1</sup>series of five patients with beauty parlor stroke syndrome postulates a plausible causal mechanism for such arterial injury. Although well documented clinically, I have some epidemiologic concerns about his observations. Since this report reflects a new syndrome, it is critical to describe the nature of the hypothetical causal variable or risk factor in a rigorous fashion.<sup>2</sup>Unfortunately, no precise descriptions of these five clients' salon visits are given. The presumed risk factor (alternatively termed<i>shampooing or shampoo treatment</i>) is not described either in the same manner or in operational terms for all cases. These details are essential to delineate "exposure" to the potential causal variable.<sup>2</sup> Weintraub does not take sufficient account of several factors unique to beauty salons. The hanging, hyperextended position, with the head cradled in a contour sink, and the body reclining in a chair applies to situations other than
MEDICAL ACTIVITY IN THE STATE UNIVERSITIES.
Journal: JAMA (1903)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Undifferentiated sarcoma. arising in previous Hodgkin's radiation field
Authors: P. R. Jochimsen
Journal: JAMA (1977)

SARCOMAS of the chest wall appearing after postoperative radiation therapy for breast carcinoma have recently been reviewed by Travis et al.<sup>1</sup>Less well documented are instances of such tumors developing in persons receiving nodal and mediastinal irradiation for Hodgkin's disease. We report such an occurrence. <h3>Report of a Case</h3> A 42-year-old woman, in 1969, had a history of fever, pruritis, and enlarged cervical lymph nodes, which were diagnosed by node biopsy as having nodular sclerosing Hodgkin's disease. Chest roentgenograms demonstrated a widened mediastinum and a large mediastinal mass consistent with Hodgkin's involvement. A lymphangiogram showed right periaortic nodes to be abnormal. Between March 11 and April 4, 1969, the patient was treated with a cobaltous chloride Co 60 mantle and received 3,550 R at the sternal notch, and 3,340 R at the xiphoid process. During this initial therapy, her systemic symptoms cleared and the mediastinal mass regressed to the
AMA Insights
Journal: JAMA (1981)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
对黑色素瘤遗传风险信息的情感和行为反应
Authors: G.L. Fenton, A.K. Smit, L. Keogh, A.E. Cust
Journal: British Journal of Dermatology (2019)

黑色素瘤是最致命的皮肤癌,而且在澳大利亚等国家,黑色素瘤患者的人数很高。进一步改善黑色素瘤预防和早期检测的新方法旨在通过分析人们的基因,然后向他们提供其黑色素瘤遗传风险信息,更好地了解他们出现黑色素瘤的几率或风险。这项在澳大利亚进行的研究探索了人们收到这种信息后的反应。访问了30人后发现,他们没有黑色素瘤个人病史,而且先前未收到遗传风险结果,以及有关如何预防黑色素瘤的信息和遗传顾问的电话访问。多个考虑因素影响参与者对其风险结果的感觉和行为,包括他们对遗传风险的预期、检测前对黑色素瘤风险的想法,以及已使用的防晒方式。存在许多积极反应,而且很多参与者称通过增加他们有关黑色素瘤的知识和了解,更好地改变了他们的日晒行为。虽然某些参与者描述产生负面情绪(如失望和担忧),但这会随时间推移得到改善。本次研究的结果提高了我们对黑色素瘤遗传风险信息情感和行为反应的了解,而且将帮助开发适用于基因检测者的教育和支持资源。
Clinical outcomes among patients undergoing elective percutaneous coronary intervention at a hospital without on-site cardiac surgery Kirk N. Garratt, Henry H. Ting, Joseph A. Dearani, Ryan Lennon, Jack T. Cusma, Katherine L. Boutchee, Douglas L. Wood, David R. Holmes, Jr. Mayo Medical Center, Rochester, MN, Immanuel St. Joseph's Hospital, Mankato, MN
Journal: Journal of the American College of Cardiology (2001)
Industrial Contributions of Arsenic to the Environment
Authors: K. W. Nelson
Journal: Environmental Health Perspectives (1977)

Arsenic is present in all copper, lead, and zinc sulfide ores and is carried along with those metals in the mining, milling and concentrating process. Separation, final concentration and refining of by-product arsenic as the trioxide is achieved at smelters. Arsenic is the essential consistent element of many compounds important and widely used in agriculture and wood preservation. Lesser amounts are used in metal alloys, glass-making, and feed additives. There is no significant recycling. Current levels of arsenic emissions to the atmosphere from smelters and power plants and ambient air concentrations are given as data of greatest environmental interest.
“THOU SHALT NOT KILL.”
Journal: JAMA (2006)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
NEPHROTOXIC NEPHRITIS
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Viral hepatitis: an occupational hazard of medical personnel. Experience of the Yalenew Haven Hospital, 1952 to 1965
Authors: E. B. Byrne
Journal: JAMA (1966)

The occurrence of eight cases of viral hepatitis over a 13-month period among employees of the Yale-New Haven Hospital dramatically refocused attention on this disease as an occupational hazard. Epidemiological investigation was undertaken to determine the circumstances immediately responsible for the cases and to estimate the degree of risk for hospital personnel for the purpose of instituting long-term countermeasures. <h3>Recent Experience</h3> The eight employee cases of hepatitis occurred in four distinct episodes during the 13-month period (Table 1). The assistant resident of episode 1, who is believed to have acquired his disease from accidental self-inoculation with fibrinogen, donated blood while in the incubation phase of his illness. This blood along with several other units was administered to a patient in whom posttransfusional hepatitis of the long-incubation type subsequently developed. Episode 2 is presumed to have been initiated by a pediatric patient (hospitalized for nephrotic syndrome) with whom all episode 2