tbuckley/cabot-search huggingface dataset:
Peroxid of Hydrogen (Medicinal) Glycozone, Hydrozone and Eye Balsam.
Journal: JAMA (1896)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Cystinuria with hyperuricemia
Authors: F. R. Meloni
Journal: JAMA (1967)

CYSTINURIA is intrinsically a nonfatal metabolic abnormality with variable morbidity. The morbidity associated with this disorder is directly related to the relative insolubility of cystine and the resulting formation of cystine stones in the urinary tract. Since concurrent chronic disease has rarely been reported in association with cystinuria, it seemed appropriate to record observations on four of six cystinuric patients who had hyperuricemia, normal renal function, and family backgrounds of hyperuricemia. These six cases of cystinuria comprise our experience with the disease. <h3>Methods and Materials</h3> The cyanide nitroprusside test<sup>1</sup>was used to test for urinary cystine. Urinary two-dimensional thinlayer chromatograms for amino acids, modified from Fahmy et al,<sup>2</sup>were examined for the presence of lysine, cystine, arginine, and ornithine. Serum and urinary uric acid were measured by the uricase method of Liddle et al. By this method, any value over 6.5 mg/100 ml indicates hyperuricemia.<sup>3</sup>The families
Current Toxicological Information as the Basis for Sulfur Oxide Standards
Authors: M. A. Mehlman
Journal: Environmental Health Perspectives (1983)

The ambient air quality standard established in 1973 is 0.03 ppm annual average for sulfur dioxide and 0.075 mg/m3 for particulates. It is now generally believed that the toxicity of sulfur oxides in ambient air is significantly influenced by the coincident presence of particulates. Inhalation of 1 ppm of sulfur dioxide for 2 hr may produce alterations in pulmonary ventilatory function, both in normal and asthmatic subjects. Effects obtained at 0.5 ppm of sulfur dioxide are controversial and of questionable biological significance. No clear evidence exists that sulfur dioxide or bisulfite causes mutagenicity in mammals, and it is concluded from a variety of animal experiments that long-term exposure to sulfur dioxide alone does not cause cancer.
Ethanol-induced changes in hepatic free radical defense mechanisms and fatty-acid composition in the miniature pig
Authors: S Zidenberg-Cherr
Journal: Hepatology (1991)

In the miniature pig, ethanol consumption has been reported to induce alterations in hepatic antioxidant defense capacity, which could result in increased risk of peroxidative damage. However, ethanol may also induce changes in membrane fatty acid composition, which could reduce the risk of peroxidative damage. This study examined lipid peroxidation, antioxidant defense and fatty acid composition in livers from miniature pigs fed ethanol in diets containing 12% of their calories as fat for 20 mo. After 12 and 20 mo of feeding, ethanol-fed pigs had higher hepatic manganese–superoxide dismutase activity, lower hepatic copper concentrations and low hepatic copperzinc–superoxide dismutase and glutathione peroxidase activities compared with controls. Lipid peroxidation as assessed by thiobarbituric acid reacting substance assay was lower in liver homogenate and mitochondrial and microsomal fractions from ethanol-fed pigs than in controls. The percentage contribution of highly unsaturated fatty acids to total fatty acids in liver homogenates (after 12 mo of feeding) and microsome fractions (after 20 mo of feeding) was lower in the ethanol-fed pigs than in the controls, resulting in a lower peroxidizability index. Ethanol-fed pigs had minimal or no hepatic damage as assessed by histological methods. We suggest that the relative resistance of microsomes to lipid peroxidation is due to the lower peroxidizability index in the ethanol-fed pigs and may account in part for the absence of significant histopathological findings after 20 mo of ethanol feeding. (HEPATOLOGY 1991;13:1185–1192.)
PREVALENT DISEASES.
Journal: JAMA (1992)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Why is diabetes mellitus a stronger risk factor for fatal ischemic heart disease in women than in men? The Rancho Bernardo Study
Authors: E. L. Barrett-Connor
Journal: JAMA (1991)

We report here the 14-year sex-specific effect of non—insulin-dependent diabetes mellitus on the risk of fatal ischemic heart disease in a geographically defined population of men and women aged 40 through 79 years. There were 207 men and 127 women who had diabetes at baseline based on medical history or fasting hyperglycemia. They were compared with 2137 adults who had fasting euglycemia and a negative personal and family history of diabetes. The relative hazard of ischemic heart disease death in diabetics vs nondiabetics was 1.8 in men and 3.3 in women, after adjusting for age, and 1.9 and 3.3, respectively, after adjusting for age, systolic blood pressure, cholesterol, body mass index, and cigarette smoking using the Cox regression model. The sex difference in the independent contribution of diabetes to fatal heart disease was largely explained by the persistently more favorable survival rate of women (than men) without diabetes. (<i>JAMA</i>. 1991;265:627-631)
Malignant hypertension secondary to idiopathic arteritis of the aorta
Authors: M. N Lowenthal
Journal: BMJ (1977)

did describe one case, in an elderly porter at the London Hospital, in 1890, before Horton in 1932, just as others had described what Barber later termed polymyalgia rheumatica in 1957, but in each case the fuller description merited the attention it attracted.Dr Paulley is also correct in saying that the ophthalmic artery and its other branches become occluded more often than the central artery of the retina.Wilkinson and Russell1 in their necropsy study of 12 patients who died with active giant-cell arteritis found a high incidence of disease of the superficial temporal, vertebral, ophthalmic, and posterior ciliary arteries with less frequent disease of the internal and external carotid and central retinal arteries.-ED,BM7.
RELATIONAL ANATOMY.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Mediastinoscopy
Authors: Robert L. Berger
Journal: JAMA (1965)

The problems associated with the preoperative diagnosis of pulmonary shadows and the criteria for operability have prompted the development of several ancillary procedures. Direct visualization of the mediastinum through an endoscopic instrument is one of the more recently advocated diagnostic methods. The author of the present monograph presents the background material and his own extensive experience with mediastinoscopy. The mediastinal anatomy and the technique of mediastinoscopy are well detailed. The need for an experienced operator is justly emphasized. In about 20% of 184 cases of pulmonary carcinoma, mediastinoscopy was the sole method of establishing the diagnosis. On the basis of tumor extension to superior mediastinal nodes, inoperability was determined in 57 cases. However, regional extension of bronchogenic carcinoma does not necessarily constitute a contraindication to either exploration or resection, so that it is questionable whether in this group of patients mediastinoscopy served a useful purpose. With noncarcinomatous pulmonary and mediastinal
THE COLLEGE WOMAN AND CHILDREN.
Journal: JAMA (1904)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
MEDICAL NEWS
Journal: JAMA (1952)

<h3>CALIFORNIA</h3><h3>Typhus Outbreak in Altadena.—</h3> A localized outbreak of endemic typhus fever has occurred in Altadena in Los Angeles County, in an area where no previous cases had been reported, according to the California State Department of Public Health. On December 15 two cases had been confirmed by laboratory tests, and tests on another dozen suspected cases were being run at the state virus laboratory in Berkeley. The outbreak is believed to have been associated with the demolition of a rat-infested barn. A state mobile laboratory was dispatched to the area so that on-the-spot examination could be made of fleas on household pets and trapped rats. <h3>Lectures on Legal Medicine.—</h3> The schools of law and medicine on the Los Angeles campus of the University of California and university extension will cooperate with the Junior Bar of the State Bar Association of California to present lectures on orientation in legal medicine
ICR Expands CanSAR Drug Discovery Platform
Journal: Cancer Discovery (2013)

The UK's Institute of Cancer Research, London has broadened its CanSAR knowledgebase, a cancer drug-discovery platform that integrates genomic, chemical, and pharmacologic data. The newly released CanSAR 2.0 adds more prediction methodologies and holds data on more than 8 million experimentally derived measurements, nearly 1 million biologically active chemical compounds, and more than 1,000 cancer cell lines.
Manuscripts Approved for JNCI, February 1 to March 1, 1965
Journal: JNCI Journal of the National Cancer Institute (1965)

Journal Article Manuscripts Approved for JNCI, February 1 to March 1, 1965 Get access JNCI: Journal of the National Cancer Institute, Volume 34, Issue 4, April 1965, Pages 551–552, https://doi.org/10.1093/jnci/34.4.551-a Published: 01 April 1965
The Doctor's Recreation Series (in Twelve Volumes).
Journal: JAMA (1904)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Relationship between the left ventricle shortening fraction value and dynamism changes of selected echo parameters during a one year observation period in patients with chronic atrial fibrillation
Authors: D. Kosior, M. Szulc, D. Wretowski, Z. Lewandowski, A. Orêziak, P. Scislo, A. Torbicki, G. Opolski
Journal: European Journal of Heart Failure (2000)
Pseudoaccountability
Authors: Jerome P. Kassirer
Journal: Annals of Internal Medicine (2001)

The public has long entrusted the medical profession to regulate its own practices, but our efforts to do so have been uneven. In place of rigorous, enforceable standards, we have sometimes reverted to pseudoaccountability: weak regulations that only give the appearance that we have been responsible in setting and enforcing high standards. We have failed to deal effectively with substandard practitioners, lagged in preventing medical errors, inadequately documented patient care in the medical record, slipped up in protecting patients in clinical research projects, and accepted financial arrangements with industry that may affect our judgment. In response, government has intervened, and threatens to intervene further with regulations that sometimes are excessively intrusive and cumbersome. To preserve our remaining autonomy, we must show that we are serious about protecting the public. Professional membership organizations must stop promulgating weak guidelines and offering evaluative methods to assess and regulate their own coveted members. Instead, they must turn over assessment of their members to arm's-length, disinterested groups. Regulatory programs must have provisions with impeccable standards, surveillance processes, and methods to deal with infractions. In planning new self-regulatory approaches, we should invite open discussion and genuine involvement by independent members of the public or the government to help ensure that our decisions about standard setting are not self-serving. Our profession has already lost much authority. We can ill afford to lose more.
Medical Relations Under Workmen's Compensation. A Report Prepared by the Bureau of Medical Economics, American Medical Association.
Journal: JAMA (1933)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Oral contraceptive use and the risk of endometrial cancer. The Centers for Disease Control Cancer and Steroid Hormone Study
Journal: JAMA (1983)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Effects of disease stage and zidovudine therapy on the detection of human immunodeficiency virus type 1 in semen
Authors: D. J. Anderson
Journal: JAMA (1992)

<h3>Objective.</h3> —To determine the prevalence and temporal expression of infectious human immunodeficiency virus type 1 (HIV-1) in the semen of HIV-1 seropositive men and to determine whether the detection of HIV-1 in semen is associated with disease stage, zidovudine treatment status, or other clinical factors. <h3>Design.</h3> —A microculture technique was used to detect infectious HIV-1 in semen from a cohort of 95 seropositive men. In addition, semen cultures were performed monthly for at least 6 months for 14 of the men. Information was obtained by interview and extracted from medical records to identify clinical variables associated with HIV-1 in semen. <h3>Patients.</h3> —Sixty HIV-1 seropositive homosexual men participating in clinical studies at the Fenway Community Health Center, Boston, Mass, and 35 HIV seropositive bisexual or heterosexual men participating in the California Partner Study of the University of California, San Francisco. <h3>Main Outcome Measures.</h3> —Semen HIV-1 culture results, seminal leukocyte counts, Centers for Disease Control (CDC) disease stage, peripheral CD4<sup>+</sup>cell counts, zidovudine therapy, HIV risk category. <h3>Results.</h3> —In the cross-sectional study, HIV-1 was cultured from the semen of nine (9%) of 95 men. Factors associated with detection of HIV-1 in semen were peripheral CD4<sup>+</sup>cell counts of 0.20× 10<sup>9</sup>/L (200/μL) or less (adjusted odds ratio [OR], 23.33; 95% confidence interval [CI], 2.89 to 175.63); symptomatic (CDC class IV) disease (adjusted OR, 6.56; 95% CI, 1.02 to 66.76); and seminal leukocytosis (&gt;1 ×10<sup>9</sup>white blood cells per liter of semen) (adjusted OR, 7.02; 95% CI, 1.28 to 39.29). Zidovudine therapy was associated with decreased detection of HIV-1 in semen (adjusted OR, 0.04; 95% CI, 0.00 to 0.63). In the longitudinal study of 14 men who had neither peripheral CD4<sup>+</sup>cells counts of 0.20 × 10<sup>9</sup>/L or less nor seminal leukocytosis, seminal HIV-1 was detected in at least one sample from six men (43%). <h3>Conclusion.</h3> —HIV-1 is more commonly found in semen from men with advanced HIV-1 infection and seminal leukocytosis but can also be cultured from semen of men with neither of these conditions. Zidovudine therapy may decrease the prevalence and/or titer of seminal HIV-1. However, all HIV-1—infected persons should continue to assume that they are potentially infectious through sexual contact. (<i>JAMA</i>. 1992;267:2769-2774)
Anesthesiology
Authors: Aaron B. Stevens, Urban H. Eversole
Journal: New England Journal of Medicine (1956)

IN an unprecedented way recent years have seen a co-ordination of effort in an attempt to push forward surgical frontiers. Pioneering has been shared by experimental and clinical surgeons and internists alike, with physiologists and pharmacologists striving to acquire more effective and safer agents and methods and to gain a better understanding of the action of the older ones. In this ceaseless quest, which at times seems to carry an almost breathless urgency, the anesthesiologist continues to occupy an intermediate position. If, among medical specialties, anesthesiology can be said to be "neither fish nor fowl," the anesthesiologist can with equal . . .