tbuckley/cabot-search huggingface dataset:
The Scientific Exhibit
Journal: JAMA (1970)

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BUBONIC PLAGUE.
Journal: JAMA (1898)

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SIGNIFICANCE OF UNEQUAL PUPILS
Journal: JAMA (1921)

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History
Journal: JAMA (2001)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Anaphylaxis from cow's milk casein
Authors: A. I. Tabar, M. J. Alvarez, S. Echechipía, S. Acero, B. E. Garcia, J. M. Olaguíbel
Journal: Allergy (1996)

The case of a 35-ear-old woman who suffered anaphylaxis after the ingestion of milk or milk-containing products is presented. Symptoms also appeared after the patient used a cosmetic which contained casein. Skin prick tests, specific IgE measurement, and immunoblotting were carried out with cow's milk extract, and its purified proteins: casein, β-lactoglobulin, and α-lactalbumin. Specific IgE to cow's milk casein was detected with the three tests. Immunoblotting revealed one band of 24 kDa approximately corresponding to the β-fraction of casein. Negative results to β-lactoglobulin and α-lactalbumin were obtained with the three methods. Symptoms were controlled by rigorous dietary and behavior measures.
Grundriss der Physiologie für Studierende und Aerzte.
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Announcements
Journal: Neuro-Oncology (2016)

Additional criteria apply.Please refer to protocol 14379-201 for full inclusion and exclusion criteria.† Patients can participate if they had some skin cancers, superficial bladder cancer (cancer that was only on the surface of the lining of the bladder), or carcinoma in situ (cancer that had not spread) of the cervix or breast that had been cured.
Postmenopausal estrogen use and heart disease risk factors in the 1980s. Rancho Bernardo, Calif, revisited
Authors: E. Barrett-Connor
Journal: JAMA (1989)

Postmenopausal estrogen use and risk factors for heart disease were assessed in 1057 women, aged 50 to 79 years, who were enrolled in an ongoing study of residents of an upper—middle-class community. From 1984 through 1987, thirty-one percent of the women reported current estrogen use, a rate equivalent to that determined in one survey of the same population done from 1972 through 1974. Compared with nonusers, current users did not have a more favorable cardiac risk factor profile before use, but users were more likely to have had a surgically induced menopause and to have been estrogen users during the survey done from 1972 through 1974. Similar to our earlier findings, current estrogen use was associated with lower weight, diastolic blood pressure, and fasting plasma glucose level than nonuse. Levels of low-density lipoprotein cholesterol were inversely related to estrogen dose; levels of high-density lipoprotein cholesterol were positively related to the duration of use. In this cross-sectional study, blood pressure and lipoprotein and plasma glucose levels were similar in women receiving estrogen alone and in women receiving combination estrogen and progestin therapy. (<i>JAMA</i>. 1989;261:2095-2100)
Cross-sectional study of a community with exceptional exposure to DDT
Authors: K. Kreiss
Journal: JAMA (1981)

The geometric mean level of total DDT in serum samples (76.2 ng/mL) from 499 persons living downstream from a defunct DDT-manufacturing plant was several times the national geometric mean (15.0 ng/mL). DDE isomers, metabolites of DDT, accounted for an average of 86.7% of total DDT. Total DDT levels increased with age, even when controlled for other independent variables also significantly associated with DDT: race, sex, fish consumption, years of residence, socioeconomic status, alcohol consumption, and serum triglyceride levels. Fish consumption, the second strongest determinant of DDT level, had one third the predictive power of age. Total DDT levels were not associated with specific illness or ill health. However, total DDT levels were positively associated with levels of serum cholesterol, triglyceride, and γ-glutamyl transpeptidase. The finding that serum DDE levels increase with age suggests that no equilibrium in body burden has been reached or that pharmacokinetics or serum/adipose partition may vary with age. (<i>JAMA</i>1981;245:1926-1930)
Effort Under Way to Enlist More Primary Care Physicians in Treatment of Substance Abuse
Authors: Charles Marwick
Journal: JAMA (1992)

AN EFFORT is under way to provide even better care for the patient with alcohol or other substance abuse problems. One of the principal ways being explored is to enlist more primary care physicians into the army of social workers, counselors, and others who currently treat the majority of those with addiction to alcohol and other drugs, including addicted persons who may be infected with the human immunodeficiency virus (HIV). The latter group is included because of the high rate of substance abuse among this population. The effort has the backing of the Department of Health and Human Services and the Bush administration. Burton J. Lee III, MD, President Bush's personal physician, cochaired a national steering committee that laid the groundwork. <h3>Barriers to Care?</h3> A series of workshops was held around the country to look at barriers to providing more quality care for the drug-abusing patient and to suggest ways
Current Views on Formation of Thyroid Hormones
Authors: Leslie J. De Groot
Journal: New England Journal of Medicine (1965)

Effect of iodide deficiency on the thyroid gland. Iodide deficiency is, in the intact human being or animal, associated with increased T/S iodide ratio, increased iodide clearance, elevated iodide uptake, increased MIT/DIT ratio and increased T3/T4 ratio.29,107,126 127 128 These alterations are largely mediated by increased TSH production, and may be viewed teleologically as an attempt by the thyroid gland to produce more active hormone from the reduced available iodine supply. Initially this result may be accomplished, but the process, at least in man, does not progress advantageously. With time a multinodular goiter containing a huge pool of . . .
Irish Journal of Medical Science, Dublin
Journal: JAMA (1967)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Clinicopathological conference. A case of early ankylosing spondylitis with fatal secondary amyloidosis.
Journal: BMJ (1968)

The patient (Case No. 227423 ; P.M. 11926) was a man aged 21 at the time of his death in 1966.His first complaint was in 1956 when at the age of 11 years he developed occasional pain with sudden onset affecting the right knee, the ankles, hips, and back.Examination at another hospital was negative and his condition improved.Two years later he complained of pain in the right knee and the hip, which became worse at night, and a general physician put forward the possibility of Still's disease.The sedimentation rate was 78 mm./hr.In 1959 he was seen for the first time at Hammersmith Hospital following a history of attacks of fever and pain in the hips, back, thighs, and knees for about 10 months.Examination at the time showed slight limitation of movement of the left hip.There was good movement of the back, and no other joints were affected.The sedimentation rate was 50 mm./hr., and the Rose-Waaler test was negative.In the following year the right knee became swollen and the spleen palpable.The sedimentation rate was 68 mm./hr., and the haemoglobin level was 9.4 g./100 ml.He was treated with prednisone at a dose of 15 mg./day falling to 7.5 mg./day, but because of poor progress he was referred again and admitted to the M.R.C. Rheumatism Unit at Taplow in 1961.At that time there was pain and swelling affecting the right elbow, the knees, and the left foot.There was also some limita- tion of the movement of the right hip.Back movements were
Poplar Demand
Authors: W. Conard Holton
Journal: Environmental Health Perspectives (1998)

Trichloroethylene (TCE) is a common industrial solvent that poses a particular pollution problem in groundwater; while TCE disappears from surface water within a few weeks, groundwater contamination can take months or years to degrade. Humans have not conclusively been shown to develop cancer in response to TCE exposure, but rats and mice exposed to TCE have an increased incidence of liver and lung cancers.
12/15-lipoxygenase orchestrates the clearance of apoptotic cells and maintains immunological tolerance
Authors: S. Uderhardt, M. Herrmann, O. Oskolikova, S. Aschermann, B. Frey, R. Voll, F. Nimmerjahn, V. N. Bochkov, G. Schett, G. Kronke
Journal: Annals of the Rheumatic Diseases (2011)

<h3>Background and objectives</h3> During inflammation and tissue damage, pathogens and dying cells are ingested by different phagocytes such as macrophages and dendritic cells. Both the nature and the activation state of the respective phagocyte determine the resulting immune response, which ranges from specific immunity to tolerance. In this context, the coordinated removal of apoptotic cells is essential to prevent autoimmunity and imposes a special task on the innate immune system. <h3>Materials and methods</h3> The authors both studied the removal of apoptotic thymocytes in vitro and the resulting immunological consequences in the pristine model of murine lupus in vivo. <h3>Results</h3> During peritonitis the removal of apoptotic cells is performed by a distinct population of alternatively activated and 12/15-LO-expressing resident macrophages (resMΦ). In the absence of 12/15-LO, this pattern was deranged and inflammatory macrophages (infMΦ) started to engulf apoptotic cells. The authors hypothesised a 12/15-LO-dependent block of phagocytosis in infMΦ and consequently identified 12/15-LO-derived oxidation products of phosphatidylethanolamine (OxPE) as the corresponding mediators, which are generated by resMΦ to selectively block ingestion of apoptotic cells by infMΦ. In contrast, phagocytosis of bacteria, micropinocytosis or the ingestion of apoptotic cells by resMΦ was unaffected. OxPE, which is exposed on the outer membrane of resMΦ in a 12/15-LO-dependent manner, bound to soluble milk fat globule-epidermal growth factor 8 protein and consequently blocked the major pathway responsible for the uptake of apoptotic cells into infMΦ. In consistence, the authors observed a break in self-tolerance in aged 12/15-LO-deficient mice including spontaneous production of autoantibodies and occurrence of glomerulonephritis, which both exacerbated after apoptotic challenge in the pristane-induced model of experimental murine lupus. <h3>Conclusions</h3> This data point towards a so far unrecognised role for lipid oxidation during the maintenance of self-tolerance and identify a mechanism, which orchestrates the cell- and context-specific uptake of antigens by different subsets of phagocytes, imposing a new paradigm in their understanding of the clearance of apoptotic cells.
Levels of Diabetes-Related Preventive-Care Practices--United States, 1997-1999
Journal: JAMA (2000)

Persons with diabetes are at increased risk for serious complications (e.g., blindness, kidney failure, nontraumatic lower-extremity amputations, and cardiovascular disease) (1). Preventive-care practices, such as annual dilated eye and foot examinations, self-monitoring of blood glucose, and glycemic control, are effective in reducing both the incidence and progression of diabetes-specific complications (2-6). Despite the benefits of preventive-care practices, many persons with diabetes in the United States do not receive these services (7). The national health objectives for 2010 include increasing the proportion of persons with diabetes who 1) have an annual dilated eye examination to 75%, 2) have an annual foot examination to 75%, 3) perform self-monitoring of their blood glucose (SMBG) at least once daily to 60%, and 4) have a glycosylated hemoglobin (HbA1C) measurement at least once a year to 50%. To measure levels of preventive-care practices, CDC analyzed data from the 1997-1999 Behavioral Risk Factor Surveillance System (BRFSS). This report summarizes the results of that analysis, which indicate that levels of preventive-care practices among persons with diabetes are lower than the national health objectives for 2010 (Figure 1).
Scotland
Journal: BMJ (1929)

diploma, nowv aged 98. Speakii,g of the airangenleiXts for holdinig primary examinations for thie Fellowship in Canada and Australia, Lord Moyniiiihan said that telo aim of tlhe Council to-day was to miiake the College the centre of surgical researlchi throughout the Emnpire.Ho then asked all present to drink the health of the donor of the baniquet, alnd announiced that on the previous day Mr. Buckston Brownio lhad been appointed a Hunterian Trustee.Tlle toast was received witlh musical lionours, anid thereafter the company adjourned to the lecture theatre to see a ciniei-matograph film of Downi House, Kenit, thle home of Chlarles Darwin.In introducing hiis Downi House film Mr. BUCsSToN BXOWNE explained that he onily did so becauise of Sir Arthur Keith's absence througlh illness." Within the last two years," he said, " Sir Arthur Keitl and I have been successful in the acquisition of this property.The house lhas been restored as far as possible to its condition in Darwiin's time.It is sixteen miles from Londort, and open freely.to all visitors on Sundays, and weekdays except onl Fridays.The ground floor is to be retainied in perpetuity as one of the sacred shrines of Science.Apart from house and gardens, there are some eiglhteen acres of land, witlh good road frontage, and it is the dream of Lord Moynihan, otur President, to establish upon this land laboratories for the prosecution of surgical biological research.John Hunter lhad .,isfarm at Earl's Court, wlhere he kept his animals and per- formed hiis experiments, and, incidentally, where he boiled the body of O'Brien, the Irish giant.We wish that the Down domain should be to the Royal College of Surgeons of Ezigland what the Earl's Court farm was to John Hunter.Such a scheme if realized will be uiniquie in the glorious story cf British surgery.Upon tbe screen youi will see the front of thle oldl house, whlere, as stated on the gate-post.' Darwin thought aind w Ioiked for forty years, am? died 1882.'The 'Old Study' will be shown, whence issued The Origin of Species, the very greatest of all scientific treatises.It fell, like a bolt from Jove, npon a too-credulous world, and shook it from pole to pole.You will see the actual chair, given by Mr. Bernard Darwin, in wlich i The r0igin was composed, and the very knee-board on which it was written.You will see the ' Sand-walk ' where Darwin walked and thought, and the AVorm stone ' in situ on the upper lawn, with which the investigation into the -work done by earthworms was nmade.Darwin's bust by Woolner, and his portrait bv the Hon.John Collier, will be seen, and the drawing-room and actual piano and couch, where Darwin rested at regular intervals and listened to his wife's music.On the piano, uinder Collier's portrait, rests an album presented to Darwiin by his German scierntific