tbuckley/cabot-search huggingface dataset:
An MRI Study of Increased Cortical Thickness in Autism
Authors: Antonio Hardan
Journal: American Journal of Psychiatry (2006)

Objective: The purpose of this study was to examine cortical thickness in autism in light of the postmortem evidence of cortical abnormalities of the disorder. Method: Magnetic resonance imaging (MRI) scans were acquired from 17 children with autism and 14 healthy comparison subjects, and sulcal and gyral thickness were measured for the total brain and for all lobes. Results: Increases in total cerebral sulcal and gyral thickness were observed in children with autism relative to comparison subjects. Similar findings were noted in the temporal and parietal lobes but not in the frontal and occipital lobes. Conclusions: These preliminary findings indicate that increased cortical thickness may contribute to the increased gray matter volume and total brain size that have been observed in autism and may also be related to anomalies in cortical connectivity.
Myeloid Growth Factors
Authors: Jeffrey Crawford, Jeffrey Allen, James Armitage, Douglas W. Blayney, Spero R. Cataland, Mark L. Heaney, Sally Htoy, Susan Hudock, Dwight D. Kloth, David J. Kuter, Gary H. Lyman, Brandon McMahon, David P. Steensma, Saroj Vadhan-Raj, Peter Westervelt, Michael Westmoreland
Journal: Journal of the National Comprehensive Cancer Network (2011)
Circulation and Transformation of Cinema; or, Did the French Invent the American Cinema?
Authors: Brunet, François
Journal: Circulation (2017)

Circulation and Transformation of Cinema; or, Did the French Invent the American Cinema?Tom GunningCirculationAs an art of moving images, cinema depends on circulation, movement. This is both literal—even mechanical, as the filmstrip moves through camera first and then the projector—and metaphorical ...AuthorTom GunningPublisherTerra Foundation for American ArtCopyright© 2017, Terra Foundation for American ArtRelated print edition pages: pp.146-177 https://doi.org/10.37862/aaeportal.00191.005 Stable URL: https://aaeportal.com/?id=-19915Copy Chapter subject tags:Motion pictures--DistributionFrench cinemaFilm criticsMotion picture actors and actressess
Effect of Thiazides on Thiamine Excretion and on Pyridoxine Metabolism
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
'Shock Teams' Test Types Of Therapy
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Insulin: Fifty Years Ago
Authors: E.J. H.
Journal: Annals of Internal Medicine (1971)

Editorials1 November 1971Insulin: Fifty Years AgoE.J. H.E.J. H.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-75-5-797 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptOn 14 November 1921 Frederick G. Banting and Charles H. Best announced to their colleagues at a regular meeting of the Physiological Journal Club of the University of Toronto (1) that they had been able to demonstrate, in laboratory experiments begun in May,an antidiabetic principle in extracts of dog's pancreas and in fetal calf pancreas.Not surprisingly, they soon facedtwo great pressures. . . . One was exerted by the diabetic patients who needed insulin. After the announcement of our findings . . . the forerunner of the thousands of letters from diabetics appeared and soon patients, many...References1. BEST C: A Canadian trail of medical research in Selected Papers of Charles H. Best. Toronto, University of Toronto Press, 1963, p. 5 CrossrefGoogle Scholar2. BANTINGBEST FC: The internal secretion of the pancreas. J Lab Clin Med 7:251-266, 1922 Google Scholar3. BEST C: Selected Papers of Charles H. Best. Toronto, University of Toronto Press, 1963, p. 89 CrossrefGoogle Scholar4. BANTINGBESTCOLLIP FCJ: Pancreatic extracts in the treatment of diabetes mellitus: preliminary report. Can Med Assoc J 12:141-146, 1922 MedlineGoogle Scholar5. STEVENSON L: Frederick Grant Banting, in Pierre Abailard—L. S. Berg, vol. 1 of Dictionary of Scientific Biography, edited by GILLISPIE CG. New York, Charles Scribner's Sons, 1970, pp. 440-443 Google Scholar6. SJÖQUIST J: Physiology or medicine 1923, in Nobel Lectures Including Presentation Speeches and Laureates' Biographies, Physiology or Medicine, 1922-1941. Amsterdam, Elsevier Publishing Co., 1965, pp. 47-48 Google Scholar7. MURRAY I: Paulesco and the isolation of insulin. J Hist Med 26:150-157, 1971 Google Scholar8. JOSLIN E: Introduction, in Selected Papers of Charles H. Best. Toronto, University of Toronto Press, 1963, pp. xviii-xix CrossrefGoogle Scholar9. MACLEOD J: Insulin and diabetes: a general statement of the physiological and therapeutic effects of insulin. Br Med J 2:833-835, 1922 CrossrefMedlineGoogle Scholar10. DUBOS R: Medical utopias, in The Dreams of Reason. New York, Columbia University Press, 1961, pp. 63-98 CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 November 1971Volume 75, Issue 5Page: 797-800KeywordsHypoglycemicsInsulinPancreasResearch laboratories ePublished: 1 December 2008 Issue Published: 1 November 1971 PDF downloadLoading ...
COUNCIL ON MEDICAL EDUCATION AND HOSPITALS
Journal: JAMA (1952)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Painful sickle cell crisis. Successful treatment with hyperbaric oxygen therapy
Authors: J. D. Reynolds
Journal: JAMA (1971)

In a 25-year-old Negro woman with painful abdominal crisis of hemoglobin sickle cell disease, therapy with hyperbaric oxygen at 2 atmospheres pressure produced dramatic subjective improvement on three separate occasions. It is suggested that hyperbaric oxygen therapy may occasionally be a useful form of treatment for painful sickle cell crisis.
Age-specific incidence of Alzheimer's disease in a community population
Authors: L. E. Hebert
Journal: JAMA (1995)

<h3>Objective.</h3> —To determine age-specific incidence rates of clinically diagnosed Alzheimer's disease. <h3>Design.</h3> —Cohort, followed a mean of 4.3 years. <h3>Setting.</h3> —East Boston, Mass. <h3>Participants.</h3> —Of 2313 persons aged 65 years and older who were initially free of Alzheimer's disease, 1601 participated in the ascertainment of incident disease (80% of survivors), 409 declined participation, and 303 died before the end of the follow-up period. A stratified sample of 642 persons received detailed clinical evaluation. <h3>Outcome Measure.</h3> —Diagnosis of new probable Alzheimer's disease through structured clinical evaluation including neurologic, neuropsychological, and psychiatric examination. Community incidence rates were computed by 5-year age groups, adjusted for gender, single year of age, length of follow-up interval, and sampling design. <h3>Results.</h3> —The estimated annual incidence of Alzheimer's disease in the population was 0.6% (95% confidence interval [Cl], 0.3% to 0.9%) for persons aged 65 to 69 years, 1.0% (95% Cl, 0.6% to 1.4%) for persons aged 70 to 74 years, 2.0% (95% Cl, 1.3% to 2.7%) for persons aged 75 to 79 years, 3.3% (95% Cl, 2.2% to 4.4%) for persons aged 80 to 84 years, and 8.4% (95% Cl, 3.7% to 13.1%) for persons aged 85 years and older. <h3>Conclusions.</h3> —The incidence of Alzheimer's disease is substantial and is approximately 14 times higher among persons older than 85 years compared with those between 65 and 69 years of age. (<i>JAMA</i>. 1995;273:1354-1359)
MILK SECRETION AND DIET
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Acute, diffuse, nontender edema of the left breast in a 50-year-old woman
Authors: D. G. Seibel
Journal: JAMA (1987)

<h3>History</h3> A 50-year-old woman presented with acute, diffuse, nontender swelling of the left breast and axilla. Low-dose plain film mammography was performed (Fig 1). Roentgenograms of the chest were obtained. The patient was referred to the Fitzsimons Army Medical Center, Aurora, Colo, 11 days later for surgery with a diagnosis of probable inflammatory carcinoma of the left breast. On admission to the medical center the patient demonstrated mild respiratory distress and showed distention of the jugular venous system and edema of the supraclavicular area bilaterally. The left breast was swollen and erythematous and showed peu-d'orange changes of the skin extending into the left arm. A large, firm mass was noted in the left axilla. Roentgenograms of the chest were repeated (Fig 2). Xeromammography was performed to better penetrate the breast (Fig 3). Multiple biopsy samples of the left breast were obtained. <h3>Diagnosis</h3> Unilateral edema of the left breast mimicking inflammatory
Hydroxyethyl Starch or Saline for Fluid Resuscitation in Intensive Care
Authors: Axel Schubert, Sindy Böttcher, Anna Eis-Hübinger
Journal: New England Journal of Medicine (2016)

asymptomatic norovirus infection was diagnosed at admission; this infection persisted until week 18 after transplantation.Although prolonged poliovirus excretion in immunodeficient persons has been estimated to be rare, 4 unrecognized VDPV excretion is a threat to the global effort to eradicate polio. 1-3Silent introduction of replication-competent VDPVs into the population and potentially in treatment wards may have serious consequences such as paralytic polio, particularly in underimmunized communities.Assessment for poliovirus excretion in children with severe immunodeficiencies who are from countries where live poliovirus vaccine is used should be considered.Effective antiviral therapy against poliovirus infection would be useful to protect VDPV-infected persons against paralysis and prevent the spread of VDPV. 5
Explaining variations in hospital death rates
Journal: JAMA (1991)

<h3>To the Editor. —</h3> Park et al<sup>1</sup>present a sophisticated analysis describing factors that influence hospital death rate. Such research helps place current assessments of hospital performance in proper perspective. However, their simulation model of randomness may be misleading. By invoking crude age-sex-race estimates of death rate, the article may have exaggerated the element of chance and thereby underestimated the importance of quality of care. Consider a hypothetical cohort of 100 patients with congestive heart failure (Table). The age-sex-race probability ofdeath for each patient is 5%. However, the cohort actually contains 95 patients with an excellent prognosis (probability of death, 1%) and five patients with a dismal prognosis (probability of death, 80%). Calculation using the refined probability estimates yields an expected death rate of five patients. Calculation using the crude age-sex-race probability yields a similar number of deaths. However, the variance of the first estimate would be much
MEDICAL CONTINGENT FEES.
Journal: JAMA (2003)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
635. Systemic Oncolytic and Immunologic Therapy for Cancer with JX-594, a Targeted Poxvirus Expressing GM-CSF
Authors: David H. Kirn, Stephen Thorne, J.K. Kim, J.Y. Oh, B.H. Park, D.E. Lee, J.S. Kim, J.E. Je, Tae-Ho Hwang
Journal: Molecular Therapy (2006)

Targeted oncolytic viruses and immunostimulatory therapeutics are being developed as novel cancer treatment platforms. These two treatment approaches can be combined through the expression of immunostimulatory cytokines from targeted oncolytic viruses as has been reported for adenoviruses and herpes viruses. Although intratumoral injection of such viruses has been associated with systemic tumor growth inhibition, eradication of distant visceral metastases was not reported. The major limitations for this approach to date have been 1) inefficient intravenous virus delivery to tumors, and 2) the lack of predictive, immunocompetent preclinical models to optimize this approach. In order to overcome these hurdles, we used 1) a targeted, thymidine kinase(-) vaccinia virus expressing human GM-CSF (hGM-CSF) for intravenous (i.v.) delivery (JX-594), and 2) we identified and extensively characterized two immunocompetent, orthotopic, replication-permissive and hGM- CSF-sensitive tumor models: a carcinogen-induced rat liver cancer model and a rabbit liver tumor model with reproducible, time- dependent metastases to the lungs. Intravenous JX-594 was well- tolerated and had highly significant efficacy, including complete responses, against orthotopic liver tumors in both models. In addition, lung metastases progressed in 100% of control rabbits (mean number 15+/−8 per animal), whereas none of the treated animals had detectable lung metastases. Tumor-specific virus replication and gene expression, systemically-detectable levels of hGM-CSF and tumor- infiltrating CTLs were also demonstrated. JX-594 holds promise as an intravenously delivered, targeted virotherapeutic. These two tumor models hold promise for the optimization of this approach. Authors are shareholders in Jennerex Biotherapeutics, Inc.
Chirurgische Krankengymnastik.
Journal: JAMA (1931)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Treating heatstroke on pilgrimage to Mecca
Journal: JAMA (1982)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Transient paralysis of the phrenic nerve associated with head injury
Authors: S. Prasad
Journal: JAMA (1976)

DIAPHRAGMATIC paralysis in patients with head injury is clinically important for two reasons: (1) it can aggravate the inevitable respiratory problems in the immediate postinjury period, and (2) it can contribute to recurrent pulmonary problems during the recovery phase. The clinical course of two children described here document these problems. During the first few days of treatment of acute head injury, attention is directed toward life-threatening problems such as intracranial bleeding, cerebral edema, and internal bleeding. Some of the less important injuries, such as fractures of the clavicle and fingers, are very often recognized during the recovery phase. One such injury that is important to be recognized during the rehabilitation phase of head injury is phrenic nerve paralysis. We have treated two children with head injury in whom recurrent respiratory problems have been associated with phrenic nerve paralysis. A third child had a clinical picture compatible with this diagnosis, but
Probilin and Pertussin.
Journal: JAMA (1907)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal