tbuckley/cabot-search huggingface dataset:
Psychological and social effects of myocardial infarction on wives
Authors: R. Mayou
Journal: BMJ (1978)

provided that there is no special morbidity associated with its use.The experience of Sculco and Ranawat4 with spinal anaesthesia has been encouraging and this technique is now being used in Gartnavel.Our results so far indicate that when spinal anaesthesia is used the operative blood loss and the post- operative DVT rate are both reduced by about 50% compared with general anaesthesia.
Examining the Anterior Right Kidney
Authors: Ann Walzer
Journal: JAMA (1979)

An anteriorly positioned lower pole of the right kidney is often unappreciated on physical examination. Yet, on review of a large number of abdominal sonograms, more than 12% of the patients had a right kidney with a lower pole sufficiently anterior in position so as to lie at the same depth as the anterior surface of the liver. In a group of patients referred for ultrasound evaluation of hepatomegaly, 20% proved to have a normal liver and an anteriorly positioned lower pole of the right kidney. (<i>JAMA</i>242:2320-2321, 1979)
Authors’ Index
Journal: Psychotherapy and Psychosomatics (1974)

A g o , Y . 2 1 8 , 2 4 0 L e s s e , S .9 4 A m k r a u t , A .A . 2 0 9 L i p o w s k i , Z .J . 2 6 4 L i p s i t t , D .R . 1 3 2 B u r t o n -B r a d l e y , B .G . 2 2 9 M o r i, S . 2 4 0 C l e g h o r n , J .M .5 5 C o r m a n e , R .H . 1 8 8 M 'U z a n , M. d e
Books Received
Journal: JAMA (1988)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Ceramide 2 (N-acetyl sphingosine) is associated with reduction in Bcl-2 protein levels by Western blotting and with apoptosis in cultured human keratinocytes
Authors: A. Di Nardo, L. Benassi, C. Magnoni, A. Cossarizza, S. Seidenari, A. Giannetti
Journal: British Journal of Dermatology (2000)

Journal Article Ceramide 2 (N‐acetyl sphingosine) is associated with reduction in Bcl‐2 protein levels by Western blotting and with apoptosis in cultured human keratinocytes Get access A. Di Nardo, A. Di Nardo Departments of Dermatology and Anna Di Nardo. E‐mail: anndinar@tin.it Search for other works by this author on: Oxford Academic Google Scholar L. Benassi, L. Benassi Departments of Dermatology and Search for other works by this author on: Oxford Academic Google Scholar C. Magnoni, C. Magnoni Departments of Dermatology and Search for other works by this author on: Oxford Academic Google Scholar A. Cossarizza, A. Cossarizza Biomedical Sciences, University of Modena and Reggio Emilia, Via del Pozzo 71, 41100 Modena, Italy Search for other works by this author on: Oxford Academic Google Scholar S. Seidenari, S. Seidenari Departments of Dermatology and Search for other works by this author on: Oxford Academic Google Scholar A. Giannetti A. Giannetti Departments of Dermatology and Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 143, Issue 3, 1 September 2000, Pages 491–497, https://doi.org/10.1111/j.1365-2133.2000.03700.x Published: 01 September 2000
Pulmonary Response to Hyperoxia: Effects of Magnesium
Authors: H. V. Dedhia, D. E. Banks
Journal: Environmental Health Perspectives (1994)

Animals and humans rapidly develop respiratory failure and die within a few days when exposed to 100% oxygen.Postmortem examination of the lungs shows histopathologic features characteristic of diffuse alveolar damage, clinically recognized as adult respiratory distress syndrome (ARDS).At the present time, there is no effective therapy available to alter outcomes in ARDS.Importantly, hypomagnesemia also is frequently observed in critically ill patients at risk of developing ARDS.In a model of hyperoxic lung injury, rats were exposed to 100% oxygen for 48, 64, and 96 hr and sev- eral experiments were performed.First, changes in the features of bronchoalveolar lavage and in alveolar macrophage function were compared in rats exposed to room air and those exposed to hyperoxia.Second, we studied the effect of hypomagnesemia on the severity of hyperoxic lung injury.Third, we evaluated the pulmonary responses to high-dose and normal-dose Mg therapy in rats exposed to hyperoxia.In all groups, hyperoxia induced significant changes in the total and differential cell counts with increased lipid peroxidation of lavaged cells, enhanced chemiluminescence from alveolar macrophages, and protein leakage into the alveolar spaces.After 48 hr of hyperoxia, oxygen-free radical formation and hydrogen peroxide production by the alveolar macrophage were diminished compared to baseline, implying a toxic effect of hyperoxia on the alveolar macrophages.Overall, hypomagnesemia tended to magnify the degree of hyperoxic lung injury, while high-dose Mg therapy tended to attenuate the effects of hyperoxia.In conclusion, in this animal model of diffuse alveolar damage, alterations in host serum magnesium levels may modulate the degree of lung damage.-
Metabolism I
Authors: H. J. Voerman, R. J. M. Strack van Schijndel, H. de Boer, A. B. j. Groeneveld, L. G. Thijs, K. Träger, H. Ensinger, T. Anhäupl, M. Georgieff, W. Geisser, L. Lind, S. Ljunghall, C. Madl, A. Kranz, E. Liebisch, O. Traindl, G. Crinun, K. Lenz, W. Druml, T. Boulain, C. Osorio-Salazar, P. Lecomte, A. Legras, C. Valat, D. Perrotin
Journal: Intensive Care Medicine (1992)
Correlation between cadmium-induced pulmonary carcinogenicity, metallothionein expression, and inflammatory processes: a species comparison
Authors: G Oberdörster, M G Cherian, R B Baggs
Journal: Environmental Health Perspectives (1994)

There is sufficient evidence for pulmonary carcinogenicity of inhaled Cd compounds in rats whereas no such evidence was found in mice and ham- sters; the evidence in humans has been termed limited, indicating significant species differences in pulmonary response to inhaled Cd.We hypothe- sized that expression of metallothionein (MT) protein in the lung after inhalation of Cd differs between species thereby providing different degrees of sequestration of Cd and protection from its effects.Rats and mice were exposed to 100 pg CdCI2 aerosols/mi3 for 4 weeks, and the presence of MT was determined in lung and free lung cell homogenates as well as by immunocytochemistry in lung sections up to 28 days postexposure.In addi- tion, pulmonary inflammatory, and cell proliferative responses were determined.Cd exposure significantly increased MT in homogenates of total lung in both species; however, no significant increase of MT in rat lung tissue after removal of free lung cells by lavage was found whereas MT was still significantly increased in lavaged mouse lung tissue throughout the postexposure time.In contrast, exposed rats showed significant increases in MT in the lavageable lung cells and mice did not.Histochemical analysis of lung sections revealed that mainly the epithelial cells of the bronchi, bronchioli, and alveoli of Cd-exposed mice expressed MT. Mice also exhibited a marked and sustained pulmonary inflammatory and cell proliferative response upon CdCI2 exposure which was not observed in rats.The retained Cd dose per gram lung was about 2-fold greater in mice, which is con- sistent with a greater deposition efficiency of inhaled Cd-aerosols in mice.The pulmonary Cd retention halftime was about twice as long in mice than in rats.The greater MT induction may offer an explanation for the resistance of mice toward the pulmonary carcinogenic effect of inhaled Cd despite a greater pulmonary inflammatory and cell proliferative effect and a greater retention halftime of lung Cd in this species.-
The bacteriology of skin cysts
Authors: W.C. Noble, Barbara Leppard, J. Thomson
Journal: British Journal of Dermatology (1975)

Journal Article The bacteriology of skin cysts Get access W.C. Noble, W.C. Noble St John's Hospital for Diseases of the Skin, Lisle Street, London WC2 Search for other works by this author on: Oxford Academic Google Scholar Barbara Leppard, Barbara Leppard St John's Hospital for Diseases of the Skin, Lisle Street, London WC2 Search for other works by this author on: Oxford Academic Google Scholar J. Thomson J. Thomson St John's Hospital for Diseases of the Skin, Lisle Street, London WC2 Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 93, Issue s11, 1 July 1975, Page 25, https://doi.org/10.1111/j.1365-2133.1975.tb06777.x Published: 01 July 1975
2021 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis
Authors: Liana Fraenkel, Joan M. Bathon, Bryant R. England, E. William St.Clair, Thurayya Arayssi, Kristine Carandang, Kevin D. Deane, Mark Genovese, Kent Kwas Huston, Gail Kerr, Joel Kremer, Mary C. Nakamura, Linda A. Russell, Jasvinder A. Singh, Benjamin J. Smith, Jeffrey A. Sparks, Shilpa Venkatachalam, Michael E. Weinblatt, Mounir Al‐Gibbawi, Joshua F. Baker, Kamil E. Barbour, Jennifer L. Barton, Laura Cappelli, Fatimah Chamseddine, Michael George, Sindhu R. Johnson, Lara Kahale, Basil S. Karam, Assem M. Khamis, Iris Navarro-Millán, Reza Mirza, Pascale Schwab, Namrata Singh, Marat Turgunbaev, Amy S. Turner, Sally Yaacoub, Elie A. Akl
Journal: Arthritis & Rheumatology (2021)

Objective To develop updated guidelines for the pharmacologic management of rheumatoid arthritis. Methods We developed clinically relevant population, intervention, comparator, and outcomes (PICO) questions. After conducting a systematic literature review, the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach was used to rate the certainty of evidence. A voting panel comprising clinicians and patients achieved consensus on the direction (for or against) and strength (strong or conditional) of recommendations. Results The guideline addresses treatment with disease‐modifying antirheumatic drugs (DMARDs), including conventional synthetic DMARDs, biologic DMARDs, and targeted synthetic DMARDs, use of glucocorticoids, and use of DMARDs in certain high‐risk populations (i.e., those with liver disease, heart failure, lymphoproliferative disorders, previous serious infections, and nontuberculous mycobacterial lung disease). The guideline includes 44 recommendations (7 strong and 37 conditional). Conclusion This clinical practice guideline is intended to serve as a tool to support clinician and patient decision‐making. Recommendations are not prescriptive, and individual treatment decisions should be made through a shared decision‐making process based on patients’ values, goals, preferences, and comorbidities.
Ski Injuries
Authors: Thomas F. Kerns
Journal: JAMA (1975)

<h3>To the Editor.—</h3> The cover illustration of the Dec 9, 1974,<i>JAMA</i>also illustrates another aspect of the skiing safety problem. Although it is apparently spring-time in the Rockies at Arapahoe, the practice of climbing the corniced leeward aspect of a ridge is risky at any time of the ski season. The problem of avalanche hazard has become increasingly great, not only involving skiers, but also snowshoers and hikers, as more people take to the mountains in the winter-time. Since the majority of avalanche incidents involving entrapment or injury are most often precipitated by the people involved, it is well to avoid any action that may increase the possibility of triggering an avalanche, such as that depicted in the cover illustration.
Medical Societies Unite Against Firearm Injuries
Authors: T. B. Cole
Journal: JAMA (2001)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Rezeptbuch der Pflanzenheilkunde: Die Verwendung der Heilpflanzen und Kräutertees in der täglichen Praxis. Von Dr. med. S
Journal: JAMA (1934)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A Terminology of Disease to Facilitate the Classification of Histories in Hospitals.
Journal: JAMA (1927)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Health related quality of life in elderly or frail patients with advanced colorectal cancer treated with dose reduced capecitabine.
Authors: Daniel Adam Breadner, Mark David Vincent, Derek J. Jonker, M. Christine Cripps, Paul Klimo, James Joseph Biagi, Wendy Lam, Anne O'Connell, Frances Whiston, Larry Stitt, Stephen Welch
Journal: Journal of Clinical Oncology (2018)

3564 Background: Palliative chemotherapy’s role is to prolong survival while minimizing treatment toxicities to preserve or improve quality of life. We have recently published a phase 2 trial of dose reduced capecitabine in elderly or frail patients with advanced colorectal cancer (aCRC). We herein provide a robust analysis of the HRQoL data from our trial. Methods: A single arm multi-centered phase II trial of dose reduced capecitabine in elderly or frail patients. Capecitabine was given at 2000 mg/m2 days 1-14 q21 days; or 1500 mg/m2 for patients with prior pelvic RT, as determined in the phase I portion of the study. Phase II participants (182 patients) were asked to complete FACT-G questionnaires at enrollment, after each cycle of capecitabine and once after cessation of the study drug, if possible. Results: 157 patients completed a baseline questionnaire (86%), and 137 patients (75%) completed at least one subsequent questionnaire. The mean baseline score was 81.6, out of a possible 108. The mean score peaked at 92 after cycle 10. The mean change from baseline was always positive. Patients achieving the minimal clinically important difference (MCID) ranged from 30% to 45% during treatment cycles. Higher baseline FACT-G score and Physical Well-being score were independently prognostic for improved survival (p = 0.006 and p < 0.0001, respectively). Time until definitive deterioration (TUDD) was longer, but not significant, in patients with a higher baseline FACT-G (p = 0.18). Conclusions: Baseline HRQoL scores were independently prognostic for survival, supporting their importance in clinical trials. Compared to full dose, reduced dose capecitabine has previously demonstrated equivocal efficacy and reduced toxicity. We have reported dose reduced capecitabine improves quality of life in elderly or frail patients with aCRC while on treatment, further supporting its use in the management of aCRC.
Active management of myocardial infarction
Authors: M C Petch
Journal: BMJ (1983)

Active management of myocardial infarctionAcute myocardial infarction is a gradual process.In animals ligation of a coronary artery causes cardiac ischaemia with immediate functional and biochemical effects-but so long as the ischaemia is limited to 15 minutes or so recovery is complete and there are no sequelae.'Longer, or repeated,2
Chemistry of the Proteids.,
Journal: JAMA (1906)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Successful Stem Cell Mobilization and Autologous Stem Cell Transplantation after Pretreatment Consisting of Bendamustine, Prednisone and Bortezomib (BPV) in 35 Patients with Newly Diagnosed/Untreated Multiple Myeloma
Authors: Wolfram Poenisch, Madlen Ploetze, Bruno Holzvogt, Marc Andrea, Thomas Zehrfeld, Doreen Hammerschmidt, Maik Schwarz, Thomas Edelmann, Cornelia Becker, Franz-Albert Hoffmann, Andreas Schwarzer, Ute Kreibich, Malvina Bourgeois, Simone Heyn, Madlen Jentzsch, Rainer Krahl, Sabine Leiblein, Thomas Schliwa, Vladan Vucinic, Haifa Kathrin Al-Ali, Gerhard Behre, Thoralf Lange, Dietger Niederwieser
Journal: Blood (2014)
Update on the Effect of a Multidisciplinary Team Clinic on Asthma Outcome for Medicaid-Eligible Inner City Children with Moderate to High-Risk Asthma
Authors: P.P. Patel, P. Munzenberger, R. Marocco, S. Taormina, W. Alame, J. Montejo, M. Pansare, E.A. Secord
Journal: Journal of Allergy and Clinical Immunology (2007)
Nocturnal Home Oximetry in Detecting the Sleep Apnea-Hypopnea Syndrome and in Working Up Hypersomnolence
Authors: Frederic Series
Journal: Annals of Internal Medicine (1994)

Letters1 March 1994Nocturnal Home Oximetry in Detecting the Sleep Apnea-Hypopnea Syndrome and in Working Up HypersomnolenceFrederic Series, MD and Yvon Cormier, MDFrederic Series, MDHopital Laval; Sainte Foy, Quebec, G1V 4G5 CanadaSearch for more papers by this author and Yvon Cormier, MDHopital Laval; Sainte Foy, Quebec, G1V 4G5 CanadaSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-120-5-199403010-00025 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:Both correspondents question the utility of nocturnal home oximetry in identifying the cause of excessive daytime sleepiness. We agree that diurnal hypersomnolence can be a major clinical manifestation of several diseases. Our study, however, was not designed to evaluate nocturnal oximetry in patients with hypersomnia but in patients suspected of having the sleep apnea–hypopnea syndrome. In our experience and that of others, no correlation exists between the respiratory disturbances index and daytime sleepiness [2], which is present in fewer than 30% of patients with mild to moderate sleep apnea–hypopnea syndrome [3]. In men 30 to 60 years of ...References1. Series F, Marc I, Cormier Y, La Forge J. Utility of home oximetry for case findings in patients with suspected sleep apnea hypopnea syndrome. Ann Intern Med. 1993; 119:449-53. Google Scholar2. Guilleminault C, Partinen M, Quera-Salva MA, Hayes B, Dement WC, Nino-Murcia G. Determinants of daytime sleepiness in obstructive sleep apnea. Chest. 1988; 94:33-7. Google Scholar3. Viner S, Szalai JP, Hoffstein V. Are history and physical examination a good screening test for sleep apnea? Ann Intern Med. 1991; 115: 356-9. Google Scholar4. Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med. 1993; 328:1230-5. Google Scholar5. Guilleminault C, Stoohs R, Duncan S. Snoring (I). Daytime sleepiness in regular heavy snorers. Chest. 1991; 99:40-8. Google Scholar Author, Article, and Disclosure InformationAffiliations: Hopital Laval; Sainte Foy, Quebec, G1V 4G5 Canada PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 March 1994Volume 120, Issue 5Page: 439-440KeywordsBreathingOxyhemoglobinSleepSleep deprivation ePublished: 15 August 2000 Issue Published: 1 March 1994 Copyright & PermissionsCopyright © 1994 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...