tbuckley/cabot-search huggingface dataset:
Pathologists urge using some horse sense to avoid doghouse when making diagnoses
Authors: M. F. Goldsmith
Journal: JAMA (1991)

TWO DOMESTIC animal diseases that increasingly are found in humans were the focus of reports at the recent annual meeting in Chicago, Ill, of the United States and Canadian Academy of Pathology. Although still rare, they are growing less so. In one, an immunosuppressed state offers an invitation to an opportunistic pathogen. In the other, no reason for the species leap is yet apparent. <i>Rhodococcus equi</i>(originally called<i>Corynebacterium equi</i>), a gram-positive, weakly acid-fast coccobacillus that is normally found in horses, has been documented in 39 patients since the first case report in 1967. All but eight of the cases occurred in the United States. At the Chicago meeting, Margie Scott, MD, Department of Pathology, Vanderbilt University Medical Center and the Veterans Administration Medical Center, Nashville, Tenn, reported on eight cases during the last 10 years in which the organism was identified in patients in those institutions. The patients ranged
MECHANICS OF FRACTURES AT THE WRIST
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Institutional Review Board (IRB) and Clinical Investigator Information Sheets to Be Updated
Journal: JAMA (1994)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Error in Table.
Journal: JAMA (1995)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Daddy Was a Doctor
Journal: JAMA (1952)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
ITALY
Journal: JAMA (1928)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Acute respiratory disease and meningococcal infection in army recruits
Authors: M. S. Artenstein
Journal: JAMA (1967)

The chronologic association of acute respiratory disease and meningococcal infection was examined in army recruits by weekly surveys of 17 basic training platoons. Nine platoons had received live, attenuated adenovirus vaccine, type 4, orally; the other eight platoons were given placebo. Severe viral respiratory disease was reduced significantly in the vaccinated group compared to the control platoons, yet meningococcal carrier rates were almost identical. Carrier rates increased progressively in both groups from initial rates of 33% to levels over 80% in the sixth week of basic training. The majority of meningococcal acquisitions occurred prior to or in the absence of viral proliferation in the upper-respiratory tract. No case of meningococcal meningitis occurred in the more than 950 individuals studied. These results suggest that viral respiratory disease is not a significant factor in meningococcal dissemination in recruits and is unlikely to be the cause of invasion following acquisition of the meningococcus in the nasopharynx.
THERAPEUTIC POTENTIALITIES OF "MUSTARD GAS"
Journal: JAMA (1931)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Asbestos exposure, smoking, and neoplasia
Authors: I. J. Selikoff
Journal: JAMA (1968)

Asbestos insulation workers, as a group, have a high risk of dying of bronchogenic carcinoma (about seven or eight times expected). We have observed 370 such workmen from Jan 1, 1963 to April 30, 1967. Our findings indicate that asbestos exposure alone is not the entire explanation. Of 87 noncigarette smokers, none died of bronchogenic carcinoma. Of 283 workmen with a history of regular cigarette smoking, 24 died of bronchogenic carcinoma, although only three were expected to die of this disease. Calculations suggest that asbestos workers who smoke have about 92 times the risk of dying of bronchogenic carcinoma as men who neither work with asbestos nor smoke cigarettes. We conclude that asbestos exposure should be minimized, that asbestos workers who do not smoke should never start, and that those now smoking should stop immediately.
Predictors of Proximal Aortic Dissection at the Time of Aortic Valve Replacement
Authors: Yskert von Kodolitsch, Ognjen Simic, Ann Schwartz, Christoph Dresler, Roger Loose, Martin Staudt, Jörg Ostermeyer, Axel Haverich, Christoph A. Nienaber
Journal: Circulation (1999)

Background —Type I aortic dissection develops in 0.6% of patients late after aortic valve replacement (AVR), and 13% of patients with type I aortic dissections have a history of AVR. Predictors of aortic dissection at AVR, however, have not been characterized. Methods and Results —A study group of 33 patients with type I aortic dissection had aortic surgery 49±55 months after routine AVR. A group of 101 controls, who did not have morphological progression of aortic diameters ≥6 years after AVR, was used to identify predictors of postsurgical dissection. Multivariate analysis identified aortic regurgitation ( P &lt;0.002) and fragility ( P &lt;0.001) or thinning of the aortic wall ( P &lt;0.007) at AVR as predictors, associated with a 14%, 22%, and 7% probability of late aortic dissection, respectively. Clamping times, types of valve prostheses, concomitant coronary artery bypass grafting, and mean ascending aortic diameters of 43±10 mm at AVR did not predict late dissection. A separate analysis of 29 nondissecting aneurysms of the ascending aorta developing 104±64 months after routine AVR revealed younger age at AVR ( P &lt;0.003) and congenitally bicuspid aortic valves ( P &lt;0.03) as predictors of late aneurysm formation. Conclusions —Aortic regurgitation combined with fragile and thinned aortic walls in patients with moderate aortic dilation may reflect aortic root disease, with a high risk for postsurgical aortic sequelae if it is treated incompletely by isolated valve replacement.
Interstitial Fibrosis and Growth Factors
Authors: Joseph A. Lasky, Arnold R. Brody
Journal: Environmental Health Perspectives (2000)

Interstitial pulmonary fibrosis (IPF) is scarring of the lung caused by a variety of inhaled agents including mineral particles, organic dusts, and oxidant gases.The disease afflicts millions of individuals worldwide, and there are no effective therapeutic approaches.A major reason for this lack of useful treatments is that few of the molecular mechanisms of disease have been defined sufficiently to design appropriate targets for therapy.Our laboratory has focused on the molecular mechanisms through which three selected peptide growth factors could play a role in the development of IPF.Hundreds of growth factors and cytokines could be involved in the complex disease process.We are studying platelet-derived growth factor because it is the most potent mesenchymal cell mitogen yet described, transforming growth factor beta because it is a powerful inducer of extracellular matrix (scar tissue) components by mesenchymal cells, and tumor necrosis factor alpha because it is a pleiotropic cytokine that we and others have shown is essential for the development of IPF in animal models.This review describes some of the evidence from studies in humans, in animal models, and in vitro, that supports the growth factor hypothesis.The use of modern molecular and transgenic technologies could elucidate those targets that will allow effective therapeutic approaches.
FRI0430 Golimumab in Refractory Uveitis Related To Spondyloarthritis. Multicenter Study of 15 Patients
Authors: N. Palmou-Fontana, V. Calvo-Río, R. Blanco, M. Santos-Gomez, E. Rubio-Romero, M. Cordero-Coma, A. Gallego-Flores, R. Verόz, I. Torre, F.F. Hernández, A. Atanes, J. Loricera, M. Gonzalez-Vela, J.L. Hernandez, M.A. González-Gay
Journal: Annals of the Rheumatic Diseases (2016)

<h3>Objectives</h3> To assess the efficacy of golimumab (GLM) in refractory uveitis associated to spondyloarthritis (SpA). <h3>Methods</h3> Multicenter study of SpA-related uveitis refractory to at least one immunosuppressive drug. The main outcome variables were degree of anterior and posterior chamber inflammation, visual acuity, and macular thickness. <h3>Results</h3> Fifteen patients (13 men/2 women; 18 affected eyes; mean age 39±6 years) were evaluated. The underlying SpA subtypes were ankylosing spondylitis (n=8), psoriatic arthritis (n=6) and non-radiographic axial SpA (n=1). The ocular involvement patterns were recurrent anterior uveitis in 8 patients and chronic anterior uveitis in 7. Before GLM they have received methotrexate (n=13), sulfasalazine (n=6), pulses of methylprednisolone (n=4), azathioprine (n=3), leflunomide (n=2) and cyclosporine (n=1). Ten of them had also been treated with TNF-α blockers; etanercept (n=7), adalimumab (n=7), infliximab (n=6), and certolizumab (n=1). GLM was given at the standard dose (50 mg/sc/monthly) as monotherapy (n=7) or in combination with conventional immunosuppressive drugs (n=8), mainly methotrexate. Most patients had rapid and progressive improvement of intraocular inflammation parameters. The median number of cells in the anterior chamber at 2 years (0 [0–0]) was significantly reduced compared to baseline findings (1 [0–3]); p=0.04). The mean best corrected visual acuity value also improved (0.84±0.3 at 2 years versus 0.62±0.3 at baseline; p=0.03). Only minor side effects were observed after a mean follow-up of 23±7 months. <h3>Conclusions</h3> Our results indicate that GLM may be a useful therapeutic option in refractory SpA-related uveitis. <h3>Disclosure of Interest</h3> None declared
Second Annual Report of the Michigan Association for the Prevention and Relief of Tuberculosis for 1909-1910.
Journal: JAMA (1910)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Books Received
Authors: Luigi Lombardo, Emanuela Morelli, Massimiliano Luciani, Fernando Bellizzi, Paola Aceto, Italo Penco, Ian M. Kronish, William F. Chaplin, Nina Rieckmann, Matthew M. Burg, Karina W. Davidson, Carlo Lai, H.J. Rogier Hoenders, Elisabeth H. Bos, Joop T.V.M. de Jong, Peter de Jonge, Martin Grosse Holtforth, Adele M. Hayes, Marielle Sutter, Katharina Wilm, Emma Schmied, Jean-Philippe Laurenceau, Franz Caspar, Richard Balon, L. Minervini, F. Antonielli Romanini, M. Solmi, A. Passamani, E. Sferrazza, F. Schifano, Ethy Dorrepaal, Kathleen Thomaes, Johannes H. Smit, Anton J.L.M. van Balkom, Dick J. Veltman, Adriaan W. Hoogendoorn, Nel Draijer, Vicent Balanzá-Martínez, Juan Carlos Ruiz-Ruiz, Anabel Martínez-Arán, Manuel Girón, Brisa Solé, José Sánchez-Moreno, Manuel Gómez-Beneyto, Eduard Vieta, Rafael Tabarés-Seisdedos, Inmaculada Fuentes-Durá, Sammy K. Cheng, Janine Dizon, Rosalind van der Lem, Nic J.A. van der Wee, Tineke van Veen, Frans G. Zitman, Jess G. Fiedorowicz, William H. Coryell, John P. Rice, Lois L. Warren, William G. Haynes, George Anderson, Satz Mengensatzproduktion, Druck Reinhardt Druck Basel, Druck Reinhardt Druck Basel
Journal: Psychotherapy and Psychosomatics (2012)
<i>Disorders of Sleep: Insomnia.</i>By Charles F. Folsom, M. D., Fellow of the American Academy of Arts and Sciences: Visiting Physician Boston City Hospital: formerly Assistant Professor of Mental Diseases, Harvard Medical School; Honorary Memnber of the Association of Medical Superintendents of American Institutions for the Insane. Reprinted from the Transactions of the Association of American Physicians, May, 1890
Journal: American Journal of Psychiatry (1891)
THE LESSON OF THE FILARIA SANGUINIS HOMINIS.
Journal: JAMA (1891)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Alveolar proteinosis. Lavage in the presence of bronchopleural fistula
Authors: D. W. Jenkins
Journal: JAMA (1975)

LUNG lavage was successful in a patient with severe pulmonary alveolar proteinosis who developed a bronchopleural fistula as a complication of an intercurrent pneumonia. <h3>Report of a Case</h3> A 36-year-old man had intermittent shortness of breath since 1962. Throughout 1969 he had received symptomatic treatment for "asthmatic bronchitis." In 1970, progressive increase in cough led to an open lung biopsy, which was diagnostic of pulmonary alveolar proteinosis. Inhalation of nebulized bronchodilators and mucolytic agents seemed effective initially. However, during a trip to Lake Tahoe (3,000 meters [10,000 feet] above sea level) he had syncope and became increasingly breathless. Subsequently he became refractory to inhalation treatments. On referral to the USAF Medical Center, Scott, Ill (September 1971), physical examination disclosed cyanosis with extreme dyspnea, tachypnea, and diffuse end-inspiratory crackling rales. Cardiac findings included a palpable pulmonic artery, right ventricular lift, accentuated pulmonic closure, and a summation gallop. A chest x-ray film
Screening for congenital hypothyroidism. Results in the newborn population of New England
Authors: M. L. Mitchell
Journal: JAMA (1978)

During the first year of operation, the New England Regional Hypothyroidism Screening Program determined the concentration of thyroxine (T<sub>4</sub>) levels in dried blood on filter paper from 129,028 infants born in Connecticut, Maine, Massachusetts, New Hampshire, and Rhode Island. Specimens from approximately 3,800 neonates were found to have levels of T<sub>4</sub>below the lower limit of normal (&lt;6.0 μg/dl) and were assayed for thyroidstimulating hormone (TSH) content. Levels of TSH were elevated (&gt;20 μU/ml) in 31 infants, 23 of whom eventually proved to have unequivocal hypothyroidism. Based on these figures and including two hypothyroid infants who were not tested, the incidence of congenital hypothyroidism in the New England region is approximately 1:5,200 births. The estimation of T<sub>4</sub>values supplemented by measurement of TSH values on specimens with low T<sub>4</sub>values has proved to be a satisfactory approach to large-scale screening for congenital hypothyroidism. (<i>JAMA</i>239:2348-2351, 1978)