tbuckley/cabot-search huggingface dataset:
Acromegaly Said to Respond to Proton Therapy
Authors: Chris Anne Raymond
Journal: JAMA (1988)

AS PHYSICIANS AND PHYSICISTS continue to refine the clinical applications for charged particles, they can point to at least one notable success story: the treatment of acromegaly, a disorder that afflicts an estimated 250 persons in the United States each year. Bernard Kliman, MD, reported at the annual Endocrine Society meeting in Indianapolis that his group at Harvard Medical School, Boston, and the Harvard cyclotron has cured 479 (85.5%) of 560 patients with acromegaly or gigantism. Cure is defined as reducing growth hormone level to less than 5 μg/L (&lt;5 ng/mL) and shrinking the soft tissue growth characteristic of the disease. (Bony growth induced by excess growth hormone must be surgically corrected.) In 431 patients for whom they have 20 years of follow-up data, the recurrence rate of 1% is "superior to all other forms of therapy," Kliman, associate professor of medicine at Harvard, said in an interview. Medical texts
Decline in rehabilitation services
Authors: M. R Brown
Journal: Journal of the Royal Society of Medicine (2002)

Emergency ambulance triageMr Thakore and colleagues (March 2002 JRSM 1 ) conclude that 55% of calls for emergency ambulances did not merit an immediate response.As they acknowledge, the design of the study was not ideal.The initial reason for the request was determined from ambulance crew and accident and emergency (A&E) data after the patient had been seen.This will almost inevitably introduce bias when applying the triage criteria, and the assessment should have been blinded.Also, it is much easier to make such determinations in hindsight, with additional time and clinical information, than when faced with a real call when one has to consider the consequences of the decision reached.It is surprising that this paper makes no reference to priority-based dispatch systems, such as the Advanced Medical Priority Dispatch System (AMPDS), as these are currently used by most ambulance services in the UK.These systems have been shown to have a low risk of serious under-prioritization of life-threatening episodes 2 .However, work that we have undertaken in Nottingham suggests that they may not be very effective in predicting low-priority 999 calls 3 .The NHS Executive has stressed the importance of developing telephone prioritization systems that will free ambulance services from having to respond to `patients who dialled 999 but who do not need emergency care' 4 .We believe this may be dif®cult to achieve.Appropriate and effective telephone triage on non-emergency 999 calls requires a greater understanding of the relationship between the initial telephone assessment by ambulance control and the subsequent outcome of the individual call.Without these data we will not be able to ensure that such a system could operate safely and we endorse the authors' views that prospective studies are essential to assess the feasibility of accurately identifying lower priority calls.
Society for Biological Therapy: Membership Information
Journal: JNCI Journal of the National Cancer Institute (1985)

Journal Article Society for Biological Therapy: Membership Information Get access JNCI: Journal of the National Cancer Institute, Volume 74, Issue 1, January 1985, Page 266, https://doi.org/10.1093/jnci/74.1.266-a Published: 01 January 1985
Respiratory distress syndrome.
Authors: M. E. Stoneman, R. M. Owens, M. Reid
Journal: BMJ (1967)

logical findings.Forty-three cases were not x-rayed, and 10 had negative radiological findings.In contrast with this, Hutchinson's cases all had positive radiological findings.We have studied 415 infants with respira- tory distress since August 1963.Of these,
Archives of Otolaryngology, Chicago
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Death from asthma in two regions of England
Journal: BMJ (1982)

The British Thoracic Association has conducted a confidential inquiry into death from asthma of adults aged 15 to 64 years resident in the West Midland and Mersey regions in 1979. Information concerning the patients, their asthma, and death was obtained by questionnaire, interview with the general medical practitioner and a relative, and from patient records. A panel of three physicians, helped by a pathologist, identified 90 patients as dying of asthma and assessed management and treatment in the last year, last month of life, and the fatal attack. They were generally chronic asthmatics, but unstable, most having suffered severe attacks previously. Corticosteroids and bronchodilator drugs were in general underprescribed or not given in sufficiently large doses. Inhaled corticosteroids and cromoglycate had frequently not been tried. The patient9s co-operation with the management of the asthma was satisfactory for only 42 of the 90 patients. For 71 of the patients the fatal attack lasted under 24 hours; of the 77 who died at home or at work, 50 did not receive any medical attention in the fatal attack. Failure to recognise the severity of the asthma by patients, relatives, and doctor often caused delay in starting appropriate treatment. The interaction of several of these adverse factors often contributed to the patient9s death. The panel considered that there were potentially preventable factors contributory to the death of 77 (86%) of the 90 patients. Within the limits of retrospective judgment the panel considered that the routine management of the asthma was often unsatisfactory as patients known to suffer severe acute attacks were often not adequately supervised or instructed in the management and treatment of their asthma. From this retrospective inquiry we concluded that closer overall supervision, including careful attention to patient education, earlier and more intensive treatment, and pre-arranged immediate admission to hospital for asthma emergencies is desirable.
Privacy Standards
Journal: JAMA (2002)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Oxygen Therapy
Authors: W. Allen CONROY
Journal: JAMA (1962)

<h3>To the Editor:—</h3> The article on "Comparative Evaluation of Oxygen Therapy Techniques," by Kory and associates (<i>JAMA</i><b>179</b>:767 [March 10] 1962) may lead many to the erroneous opinion that the so-called nasal cannula is an effective technique for oxygen therapy. For one thing, the authors do not detail their method of taking end-expiratory (alveolar air) samples. It would make quite a difference whether the subjects exhaled these samples from the mouth, nose, or directly from a sampling tube with its tip in the bronchi, as was done by Wineland and Waters in 1931. If sampling is done from nose or mouth, incoming oxygen would contaminate the exhaled air, giving a false high reading. Perhaps the authors can clear up this point. Secondly, this series of tests was done with<i>nasopharyngeal</i>oxygen catheters, not with an<i>oropharyngeally</i>placed catheter delivery tip. Waters has long emphasized that the delivery tip of
Vllth Symposium of the International Association for Comparative Research on Leukemia and Related Diseases
Journal: JNCI Journal of the National Cancer Institute (1975)

Vllth Symposium of the International Association for Comparative Research on Leukemia and Related Diseases Get access JNCI: Journal of the National Cancer Institute, Volume 54, Issue 4, April 1975, Page 1017, https://doi.org/10.1093/jnci/54.4.1017 Published: 01 April 1975
Problems identified by secondary review of accepted manuscripts
Authors: J. M. Garfunkel
Journal: JAMA (1990)

To test the hypothesis that no important deficits would be identified on further review of accepted manuscripts, and that such manuscripts would be recommended for publication on rereview, we sent manuscripts that had been accepted for publication, after review and revision, for rereview by new referees who were unaware of the status of the manuscripts. Each review was evaluated independently by two assistant editors to determine whether substantive criticisms were identified by the new reviewers. The majority of manuscripts were thought by the new reviewers to have defects that warranted further revision, but the problems noted were often dissimilar. However, 80% of the manuscripts were recommended for publication and others were judged suitable for publication, although not at a high priority. The assistant editors frequently differed in their judgments whether a given criticism of a reviewer warranted further revision; nevertheless, there was infrequent disagreement regarding the basic decision for acceptance or rejection. (<i>JAMA</i>. 1990;263:1369-1371)
Truth is stranger than fiction department: the surgeon, the radiologist, the authors, and JAMA got it right
Authors: J. S. Najarian
Journal: JAMA (1990)

<h3>To the Editor. —</h3> When I read the article entitled "Reperfusion Pulmonary Edema,"<sup>1</sup>I was confused by the roentgenograms in Fig 2, in which the preoperative chest film is clearly that of a female patient and the postoperative chest film taken 5 hours after aneurysmectomy is a male patient. Is there a mix-up in the roentgenograms, or was some other surgical procedure performed as well?
From the Centers for Disease Control. Infant mortality--United States, 1988
Journal: JAMA (1991)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A prospective two-year study of functional restoration in industrial low back injury. An objective assessment procedure
Authors: T. G. Mayer
Journal: JAMA (1987)

One hundred sixteen consecutive patients entered a functional restoration treatment program for chronic low back pain and were compared with 72 patients not treated. A two-year follow-up survey reached more than 85% of both groups; its findings were compared with earlier results of a five-month and one-year follow-up. Analysis demonstrated that 87% of the treatment group was actively working after two years, as compared with only 41% of the nontreatment comparison group. Moreover, about twice as many of the comparison group patients had additional spine surgery relative to the treatment group. The comparison group continued with an approximately five times higher rate of patient visits to health professionals in the second year as the treatment group. Also, treatment group reinjury rates were no higher than those expected in the general population, while nontreatment subjects had a higher incidence of reinjury. Finally, a small treatment "dropout" group did poorest of all, with results in almost all areas even worse than those of the comparison group patients. (<i>JAMA</i>1987;258:1763-1767)
THE DEPARTMENT OF PUBLIC HEALTH.
Journal: JAMA (1895)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Highlights
Journal: JAMA (2017)

Time to Colonoscopy and Risk of Colorectal Cancer 1631Patients screened for colorectal cancer (CRC) who have positive fecal immunochemical test (FIT) results require a follow-up colonoscopy to identify neoplasms or preneoplastic polyps.In practice, the time to follow-up colonoscopy varies, and the risk of neoplastic progression associated with a delayed colonoscopy is unknown.In a retrospective cohort study of 70 124 patients with positive FIT results, Corley and colleagues report that followup colonoscopy after 10 months, compared with follow-up colonoscopy at 8 to 30 days, was associated with a higher risk of CRC and more advanced-stage disease at the time of diagnosis.In an Editorial, Rutter and Inadomi suggest that the lack of urgency to have a colonoscopy immediately after a positive FIT result refl ects the clinical understanding that colorectal cancer develops slowly.
Rapidly progressive dyspnea in a teenage boy. Clinical pathological conference
Authors: Averill A. Liebow, Kenneth M. Moser, M. Therese Southgate
Journal: JAMA (1973)

<h3>[Protocol]</h3> A 15-year-old white boy first noted some mild dyspnea in the summer of 1963, while riding his bicycle. At that time he lived in Massachusetts. No cause for the dyspnea was apparent, but it was progressive until, during the following winter, he developed a "cold" with dry cough and had to be hospitalized because of marked dyspnea. He was treated for pneumonia with right pleural effusion. Shortly thereafter the family moved to Florida, and the boy was hospitalized at Fort Myers in late March because of increasing dyspnea as well as the onset of cyanosis. He also had marked fatigue and some weight loss with vomiting during the few days immediately preceding hospitalization. The history disclosed that the boy had had prolonged colds each winter accompanied by wheezing, and that for several years he had been intermittently exposed to chickens on a neighbor's farm. No history was obtained of
Classified Advertising
Journal: JAMA (1991)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Author's reply
Authors: M. A F J Van De Laar, J. K Van Der Korst
Journal: Annals of the Rheumatic Diseases (1993)

Food intolerance in rheumatoid arthritisSir: We read with interest the two papers by Drs van de Laar and van der Korst on food intolerance in rheumatoid arthritis (RA). 1 2 It appears from this extensive but short study of patients with seropositive RA that rheumatoid disease in a small subgroup is sensitive to dietary manipulation.Identification of these patients is, however, a problem.We have previously shown that significant gut abnormalities are associated with raised levels of IgA rheumatoid factor (RF) and dietary protein specific IgG in patients with RA and suggested that these changes might identify patients who would respond to dietary manipulation.3Gendre and colleagues have described villous atrophy and other histological abnormalities of the small intestine in patients with RA.4These changes were more significant among IgM RF negative patients (who are often IgA RF positive).In the recent study the number of patients examined histologically was small, therefore a firm conclusion cannot be reached.Moreover, it is likely that by excluding IgM RF negative patients with RA some food intolerant patients might have been missed.Furthermore, investigation of intestinal structure and function in RA is severely hampered by the damaging effects of non-steroidal anti-inflam- matory drugs, which are so often used by patients with RA.Thus a fundamental question remains extremely difficult to answer-that is, whether gut abnormalities and any of the manifestations associated with these abnor- malities in patients with RA are secondary to the disease process and its treatment or are of primary pathogenic significance.
Psychiatric symptoms in disliked medical patients
Authors: J. M. Goodwin
Journal: JAMA (1979)

Twenty-two patients seen in a clinic for systemic lupus erythematosus were tested for organicity, depression, anxiety, and hostility. Four of the clinic's physicians ranked these patients from most liked to least liked. In three of the four physicians, dislike was significantly correlated with the patient's degree of organicity. Ten of the patients were ranked among the three most disliked patients by one or more of the ranking physicians. This group of most disliked patients contained all patients with signs of organic brain damage and all suicidal patients. Dislike of a patient by the physician may be a clue to serious psychiatric impairment. (<i>JAMA</i>241:1117-1120, 1979)
Tuberculosis of the Lungs. A Practical Guide for General Practitioners.
Journal: JAMA (1927)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The real Doctor Guillotin
Authors: D. B. Weiner
Journal: JAMA (1972)

The guillotine, the beheading mechanism widely used in the French Revolution, is familiar to everyone. Yet historians hardly know the real Dr. Guillotin. A recent popular biography is a sensationalist travesty; journals in many languages contain short pieces on the guillotine irrelevant to Dr. Guillotin's life. A scholarly article might be technical and discuss the shape of the deadly blade—it evolved from crescentshaped to diagonal—because the surgeon Antoine Louis demonstrated on sheep that diagonal instruments make neater incisions. Elsewhere an author might discuss whether "life" lingered in the severed head or body, and adduce contemporary evidence that a head managed a prearranged wink at the audience. Or again a writer might explore the reasons why the name "guillotine" stuck to a machine that Guillotin neither invented nor christened. The famous doctor himself has left us no books or articles that might reveal his personality. This may be one reason why