tbuckley/cabot-search huggingface dataset:
Clinical Lecture on Bone and Joint Changes in Connection with Thoracic Disease: Delivered at the Hospital for Consumption and Diseases of the Chest, Brompton
Authors: R. J. Godlee
Journal: BMJ (1896)

CASES OF PULMONARY OSTEOARTHROPATHY.WILL now give very brief notes of eases that have come under my own notice.Some of them appear to me as genuine as many of the recorded cases; others I merely put in for comparison and in order to illustrate what seems to me to be the confusion that surrounds the subject.CAsE i (referred to above).-Ayouth, aged about ig, had had for years a long piece of drainage tube in his pleura.I think it was II inches for e years.had slipped in soon after the opening of an empyema.He had marked clubbing of the fingers and toes and nose, and very obvious swelling of the wrists and ankles, and, I think, knees;but I did not take careful notes of them.Thetube was removed bySir Joseph Lister.The empyema closed, and the clubbing and theswelling of the joints quite disappeared.I have no doubt that this would have been considered a typical case.Some years later he died of pneumonia, so I can- not now obtain any details or dates.CAsE II.-In x888 a patient came under my care for chronic empyema associated with tubercle.He was then 31 years of age.His troubles began in x88o, eight years before I saw him, with pleurisy, fow ed by empyema, which had been opened in the posterior axillary lie had asmall cavity as large as the palm of the hand in the pos- terior and lower partof the right axilla, which I opened up by resecting 3 inches of three ribs, and removed a large quantity of calcareous
Iron Deficiency Associated with Higher Blood Lead in Children Living in Contaminated Environments
Authors: Asa Bradman, Brenda Eskenazi, Patrice Sutton, Marcos Athanasoulis, Lynn R. Goldman
Journal: Environmental Health Perspectives (2001)

The evidence that iron deficiency increases lead child exposure is based primarily on animal data and limited human studies, and some of this evidence is contradictory. No studies of iron status and blood lead levels in children have accounted for environmental lead contamination and, therefore, the source of their exposure. Thus, no studies have directly determined whether iron deficiency modifies the relationship of environmental lead and blood lead. In this study, we compared blood lead levels of iron-deficient and iron-replete children living in low, medium, or highly contaminated environments. Measurements of lead in paint, soil, dust, and blood, age of housing, and iron status were collected from 319 children ages 1-5. We developed two lead exposure factors to summarize the correlated exposure variables: Factor 1 summarized all environmental measures, and Factor 2 was weighted for lead loading of house dust. The geometric mean blood lead level was 4.9 microg/dL; 14% exceeded 10 microg/dL. Many of the children were iron deficient (24% with ferritin < 12 ng/dL). Seventeen percent of soil leads exceeded 500 microg/g, and 23% and 63% of interior and exterior paint samples exceeded 5,000 microg/g. The unadjusted geometric mean blood lead level for iron-deficient children was higher by 1 microg/dL; this difference was greater (1.8 microg/dL) after excluding Asians. Blood lead levels were higher for iron-deficient children for each tertile of exposure as estimated by Factors 1 and 2 for non-Asian children. Elevated blood lead among iron-deficient children persisted after adjusting for potential confounders by multivariate regression; the largest difference in blood lead levels between iron-deficient and -replete children, approximately 3 microg/dL, was among those living in the most contaminated environments. Asian children had a paradoxical association of sufficient iron status and higher blood lead level, which warrants further investigation. Improving iron status, along with reducing exposures, may help reduce blood lead levels among most children, especially those living in the most contaminated environments.
Mental Disorders Briefly Described and Classified, with a Few Remarks on Treatment and Prevention.
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Sulfuric Acid-Induced Changes in the Physiology and Structure of the Tracheobronchial Airways
Authors: Jeffery M. Gearhart, Richard B. Schlesinger
Journal: Environmental Health Perspectives (1989)

Sulfuric acid aerosols occur in the ambient particulate mode due to atmospheric conversion from sulfur dioxide (SO2). This paper describes the response of the rabbit tracheobronchial tree to daily exposures to sulfuric acid (H2SO4) aerosol, relating physiological and morphological parameters. Rabbits were exposed to filtered air (sham control) or to submicrometer-sized H2SO4 at 250 micrograms/m3 H2SO4, for 1 hr/day, 5 days/week, with sacrifices after 4, 8, and 12 months of acid (or sham) exposure; some rabbits were allowed a 3-month recovery after all exposures ended. H2SO4 produced a slowing of tracheobronchial mucociliary clearance during the first weeks of exposure; this change became significantly greater with continued exposures and did not improve after exposures ended. Airway hyperresponsiveness was evident by 4 months of acid exposure; the condition worsened by 8 months of exposure and appeared to stabilize after this time. Standard pulmonary mechanics parameters showed no significant trends with repeated acid exposure, except for a decline in dynamic lung compliance in animals exposed to acid for 12 months. Lung tissue samples obtained from exposed animals showed a shift toward a greater frequency of smaller airways compared to control, an increase in epithelial secretory cell density in smaller airways, and a shift from neutral to acidic glycoproteins in the secretory cells. The effect on airway diameter resolved after the exposures ceased, but the secretory cell response did not return to normal within the recovery period. No evidence of inflammatory cell infiltration was found due to H2SO4 exposure. Thus, significant alterations in the physiology of the tracheobronchial tree have been demonstrated due to repeated 1-hr exposures to a concentration of H2SO4 that is one-fourth the current 8-hr threshold limit value for exposure in the work environment. The cumulative dose inhaled by the rabbits is similar to current peak daily doses from ambient exposure in North America. The results obtained in the rabbit model provide insight into early changes in the tracheobronchial tree due to repeated irritant exposure and may be involved in the pathogenesis of chronic airway disease.
Brucellosis Control
Authors: William R. Barclay
Journal: JAMA (1980)

Modern medicine has reduced morbidity and mortality primarily through the control of infectious diseases. Unfortunately, we may have grown too complacent about this success, believing that infectious diseases require relatively little in continuing or new effort to achieve their suppression or eradication. Consequently, physicians have turned the greater part of their research and clinical interest to degenerative, cardiovascular, and neoplastic diseases. In this issue ofThe Journal(p 2318), Robert I. Wise, MD, PhD, reviews the problem of eradicating brucellosis from animal herds and man, a challenge with profound economic as well as health implications. Brucellosis is transmitted from animal to animal and from animal to man but seldom from man to man. Breaking the chain of transmission demands full cooperation among farmers, abattoirs, government, veterinarians, and physicians. The responsibility of physicians is relatively simple and straightforward: they must recognize the disease when they encounter it and must promptly report
Erratum
Journal: BMJ (1903)

OltIG:N tL AItlrICLES and LETTERS fborwcardejjbr pnbl'eltinn are understoodt to be o ft-eu 1(t the BiIlTISI I%IEDICAL JOURNAL U /9i7e, Miteu li1e contrary be stlatel.A UTaois des'ring repritits of their airticles pulAlished in the IiIiITISH 1EDICAL JOURNA.. arte requlested to
A Short History of Nearly Everything
Authors: C. Martyn
Journal: BMJ (2003)

Bill Bryson Doubleday, £20, pp 528 ISBN 0385408188 Rating: ![Graphic][1]</img> In 1993, when there was a Tory government in the United Kingdom, the then minister for science, William Waldegrave, issued a challenge to physicists who were lobbying him for money to pay for their colossally expensive experiments. Could they answer, on a single page of A4, the questions: “What is the Higgs boson, and why do we want to find it?” As it happened, they could, as you can see by going to http://hepwww.ph.qmw.ac.uk/epp/higgs.html. But the incident prompts questions about the way the United Kingdom decides priorities in funding its research. Might it not be better to have a minister who knew something about his portfolio? And it reminds us … [1]: /embed/inline-graphic-1.gif
Book Review The Embryology of Behavior: The beginnings of the human mind. By Arnold Gesell, M.D., Ph.D., Sc.D. In collaboration with Catherine S. Amatruda, M.D. 8°, cloth, 289 pp., with 78 illustrations, 44 plates and frontispiece. New York: Harper and Brothers, 1945. $5.00.
Journal: New England Journal of Medicine (1946)
OFFICIAL MINUTES—GENERAL MEETINGS
Journal: JAMA (1907)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Diet in Health and Disease.
Journal: JAMA (1906)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Weighty Choices: Selecting Optimal G-CSF Doses for Stem Cell Mobilization to Optimize Yield
Authors: Nosha Farhadfar, Jack W. Hsu, Brent R. Logan, Jennifer A. Sees, Pintip Chitphakdithai, Dennis L. Confer, Michael A. Pulsipher, Nirali N. Shah, Galen E. Switzer, Bronwen E. Shaw, John R. Wingard
Journal: Blood (2018)
Hyperthyroidism with painless subacute thyroiditis in the elderly
Authors: M. Gordon
Journal: JAMA (1981)

Six elderly patients experiencing weight loss, palpitations, or depression had the biochemical and clinical features of masked hyperthyroidism due to painless subacute thyroiditis. The syndrome is not commonly recognized in this age group and can be easily misdiagnosed unless appropriate investigations are undertaken. Supportive and symptomatic therapy is sufficient during the hyperthyroid phase of the disorder. (<i>JAMA</i>1981;246:2354-2355)
AN INVESTIGATION INTO THE CAUSE OF HYPERTENSION
Journal: JAMA (1934)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
15-lipoxygenase immunoreactivity in normal and in asthmatic airways.
Authors: P Bradding, A E Redington, R Djukanovic, D J Conrad, S T Holgate
Journal: American Journal of Respiratory and Critical Care Medicine (1995)

Products of the 15-lipoxygenase (15-LO) pathway of arachidonic acid metabolism such as the mono- and di-hydroxyeicosatetraenoic acids (HETEs) may contribute to the pathophysiology of allergic airway inflammation through the recruitment and activation of inflammatory cells and stimulation of glandular secretion. In this study we have examined the expression of 15-LO and its cellular localization in the asthmatic and normal bronchial mucosa. Bronchial mucosal biopsies were obtained by fiberoptic bronchoscopy from 10 patients with symptomatic allergic asthma and six normal control subjects and processed into glycolmethacrylate resin. Sections 2 microns thick were immunostained using a specific rabbit polyclonal antihuman 15-LO antibody. Strong immunoreactivity for 15-LO was present throughout the epithelium in both the asthmatic and the normal subjects, with no difference between the two groups. Cells expressing 15-LO immunoreactivity were also present in the submucosa of both groups, with a significantly greater number present in the asthmatic group (median, 15.3 cells/mm2) than in the normal group (median, 6.9 cells/mm2) (p = 0.01). The majority (85%) of the submucosal 15-LO+ cells were eosinophils. Patchy 15-LO immunoreactivity was also seen in the vascular endothelium in both groups. These findings demonstrated increased 15-LO expression in the bronchial submucosa of asthmatic subjects, and they suggest that 15-LO products in asthma originate from both bronchial epithelium and infiltrating eosinophils.
Natural history of left ventricular function and size in asymptomatic patients with chronic severe aortic regurgitation and initially normal resting function: Relation of temporal patterns to adverse cardiac outcome Phyllis G. Supino, Jeffrey S. Borer, Clare A. Hochreiter, Edmund M. Herrold, Richard B. Devereux, Mary J. Roman, Paul Kligfield, Andrew Yin. Weill Medical College of Cornell University, New York, NY
Journal: Journal of the American College of Cardiology (2001)
MISCELLANY.
Journal: JAMA (1896)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Influenza-related mortality
Authors: M. B. Gregg
Journal: JAMA (1978)

ALBERT Sabin, MD,<sup>1</sup>in an article published in<i>JAMA</i>takes issue with estimates of influenza-related mortality published by the Center for Disease Control (CDC) and current recommendations for yearly influenza immunization of persons assumed to be at high risk of dying from influenza. Sabin's conclusions are based on analyses of recent morbidity and mortality data published by CDC and the National Center for Health Statistics (NCHS). We believe the methods Sabin used in his analyses obscure important epidemiologic features of influenza and, hence, lead him to draw incomplete and erroneous conclusions regarding the impact of influenza in the United States and thebenefits of annual influenza immunization of those at high risk. <h3>Sabin's Analytic Methods</h3> Three aspects of Sabin's analytic methods are inappropriate to a thorough understanding of influenza epidemiology and its relationship to epidemic-associated mortality. These include (1) use of the calendar year rather than an epidemiologic year as
DERMATITIS REPENS.
Authors: M. B. HARTZELL
Journal: JAMA (1902)

In 1888 Crocker first called attention to a peculiar inflammation of the skin to which, he gave the name dermatitis repens, his description of the disease being based on three cases, of which the following is a brief summary: <h3>Case 1.</h3> —The first case occurred in a young man who had had a portion of a finger amputated on account of an injury. The operation wound healed in normal fashion, but at its border a dermatitis, resembling in a general way an eczema rubrum, began which gradually spread up to the palm and over the fingers. The surface was denuded of its epidermis, was intensely red, oozing a clear fluid like sweat from numerous points around the sharply defined borders of the patch, which consisted of undermined epidermis elevated by fluid. The inflammation continued to extend for some months until it reached the elbow, the hand in the interval having recovered
L'hydrothérapie médicale.
Journal: JAMA (1930)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Landry-Guillain-Barré Syndrome After Chicken Pox
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal