tbuckley/cabot-search huggingface dataset:
Guidelines for management of asthma in adults: II--Acute severe asthma. Statement by the British Thoracic Society, Research Unit of the Royal College of Physicians of London, King's Fund Centre, National Asthma Campaign.
Journal: BMJ (1990)

In last week's issue guidelines on the management of chronic persistent asthma in adults were published.'The present article gives guidance on the management of acute severe asthma in adults and emphasises the importance of objective measurements.It is presented in the form of directions designed to help doctors attending patients with exacerbation of asthma in the home, in the accident and emergency department, and during the later stages of hospital admission.The severity of an attack of acute severe asthma is often underestimated by patients, their relatives, and their doctors.This is largely because of failure to make objective measurements.If not recognised and not treated appropriately such attacks can be fatal. Aims ofmanagementThe aims of management of acute severe asthma are: * To prevent death * To restore the patient's clinical condition and lung function to their best possible levels as soon as possible * To maintain optimal function and prevent early relapse.Recognition and assessment of acute severe asthma Potentially life threateningfeaturesThe presence of any of the following indicates a severe attack of asthma.* Increasing wheeze and breathlessness so that the patient is unable to complete sentences in one breath or get up from a chair or bed * A respiratory rate -25 breaths/min * A heart rate persistently > 110 beats/min * A peak expiratory flow <40% of predicted normal or of the best obtainable result if known (<200 1/min if the best obtainable result is not known) * An inspiratory fall in systolic blood pressure of IdOmm Hg. Imminently life threatening featuresThe presence of any of the following indicates a very severe attack of asthma.* A silent chest on auscultation * Cyanosis * Bradycardia * Exhaustion, confusion, or unconsciousness.Arterial blood gas tensions Arterial blood gas tensions should always be measured in patients with acute severe asthma who are admitted to hospital.The following are markers of a very severe (or life threatening) attack: * A normal or high arterial carbon dioxide tension (Paco2) in a breathless asthmatic patient * Severe hypoxia: arterial oxygen tension (Pao2) <8 kPa irrespective of treatment with oxygen * A low pH value.
<TITLE>Are you obese?</TITLE>
Journal: JAMA (1999)

public service of JAMA and the AMA.The information and recommendations appearing on this page are appropriate in most instances; but they are not a substitute for medical diagnosis.For specific information concerning your personal medical condition, JAMA and the AMA suggest that you consult your physician.This page may be reproduced noncommercially by physicians and other health care professionals to share with patients.Any other reproduction is subject to AMA approval.
Incidental Appendectomy
Authors: Moritz M. Ziegler
Journal: JAMA (1978)

<h3>To the Editor.—</h3> Statistical analyses have indicated the logic of incidental appendectomy especially in the younger population,<sup>1</sup>and that this procedure is practical is confirmed by recommendations by more than half of the training directors in surgery and obstetrics/gynecology.<sup>2</sup>If an argument is still made criticizing incidental appendectomy, it usually has as its basis fear of opening an otherwise sterile peritoneal cavity to the potential contamination of the appendiceal lumen, but using inversion-ligation appendectomy negates this problem. Inversion appendectomy was first described in 1895 by Dr George Edebohls,<sup>3</sup>and its wide use in obstetrics and gynecology was emphasized more than 60 years later.<sup>4</sup>Its application to pediatric surgery was suggested in 1968<sup>5</sup>and later was modified to the current practice of inversion with ligation of the stump<sup>6</sup>; this technique has been done in several hundred children of all ages without a known complication at
The effects of limitation of acitivity upon the human body
Authors: F. J. Kottke
Journal: JAMA (1966)

The functional capacity of any organ is dependent within physiological limits upon the intensity and frequency of its activity. Although rest may be protective for a damaged organ it results in progressive loss of functional capacity for normal organs. Limitation of activity during prolonged bed rest causes significant deterioration of multiple organ systems including the skeletal, neuromuscular, cardiovascular, respiratory, urogenital, and nervous systems. Total inactivity of muscle results in loss of strength of approximately 3% per day. Neuromuscular and emotional control and intellectual performance are all impaired by prolonged bed rest. Cardiovascular function decreases during bed rest more rapidly than it is restored when activity is resumed. Years may be required to restore the calcium lost from the skeleton during immobilization.
Total Protein/Protein Nitrogen Ratio of Human Serum: A Factor Consistent with Total Solids
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE EDUCATION OF THE PUBLIC.
Journal: JAMA (2005)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
AMA offers recommendations for vaccine injury compensation
Journal: JAMA (1984)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Miniature battery foreign bodies in auditory and nasal cavities
Authors: K. T. Kavanagh
Journal: JAMA (1986)

A series of cases involving button batteries lodged in the ear or nasal cavity is presented. All produced tissue destruction. Injuries were generally severe, and included tympanic membrane perforation (three patients) or total destruction (three), marked necrosis of dermis of the external ear canal with exposed bone (seven), documented further impairment of hearing (three), destruction of ossicles (two), facial nerve paralysis and chondritis (one), nasal septal perforation (one), and superficial burns of nasal mucosa (one). Otic and nasal drops must be withheld as they provide an external electrolyte bath for the battery, enhancing leakage and generation of an external current, with subsequent tissue electrolysis and hydroxide formation. Instead, batteries lodged in the ear or nose must be removed promptly. (<i>JAMA</i>1986;255:1470-1472)
Daniel LeClerc (1652-1728), medical historian
Journal: JAMA (1968)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Novel therapeutics and pharmacology, biological approaches
Authors: Gianfranco Moh'd Suleiman, Jacques Pesce, Sabine Bernier, Chnstos Christodoulou, Dimitnos Bafaloukos, Pans Kosmidis, Epaminondas Samantas, Aristotle Bamias, Pavlos Papakostas, Athanasios Karabelis, Charalabos Bacoyiannis, Dimosthenis Skarlos, Lesley Seymour', Hal Hirte, Shaniah Stafford, Glenwood Goss', Wilson Miller, Hal Belfer, Gerald Batist, Patricia Hanna', Sarah Matthews, Steven Averbuch, Hilary Calvert', Cristiana Sessa, James Carmichael, Paula Calvert, Massimo Zucchetti, Silvia Marsoni, Sabine Van Den Bosch, Angela Robinson, Elena Verdi, Gabnella Camboni, Miguel Angel, Molina Jordi Codony-Servat, Federico Rojo, Joaqum Arribas, Joan Albanell, Evanqelos Briasoulis, Dimitra Rammou, Elefthena Tzamakou, Vasilis Karavasilis, Anatoli Loannidou, Kalliopi Soulti, Nicholas Pavlidis, Carmen Munoz, Marisa Munoz, Carmen Balafia, Jose Ponton, Margarita Garcia, Angeles Llorens, Mercedes Gimeno, Rafael Rosell, Jose Germa, Miguel Izquierdo
Journal: Annals of Oncology (2000)
Gastric Cancer as a Sequel to Gastritis, Particularly the Gastritis of Pernicious Anemia
Authors: G. P. Rhoads
Journal: JNCI Journal of the National Cancer Institute (1941)

Journal Article Gastric Cancer as a Sequel to Gastritis, Particularly the Gastritis of Pernicious Anemia Get access G. P. Rhoads G. P. Rhoads director Memorial Hospital for the Treatment of Cancer and Allied Diseases, New York Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 1, Issue 4, February 1941, Pages 511–522, https://doi.org/10.1093/jnci/1.4.511 Published: 01 February 1941
Experts call for younger men to be offered PSA test for prostate cancer
Journal: BMJ (2016)

Thank you for your interest in spreading the word about The BMJ.NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address. Username * Your Email * Send To * You are going to email the following Experts call for younger men to be offered PSA test for prostate cancer Your Personal Message CAPTCHA This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Evaluation of the Sweat Chloride Assay in Adults: Use of Pilocarpine Iontophoresis
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Deaths
Journal: JAMA (1961)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Frequent Fumers: Airport Study Shows Smoke Gets to Your Heart
Authors: Ed Susman
Journal: Environmental Health Perspectives (2001)

Too Dangerous to Dip? Marine Pollution Makes Swimmers SickReports of illness after exposure to marine water appear to be increasing, and there is evidence that the rate of infection is proportional to both the amount of time swimmers are exposed and the levels of pollution in the waters where they swim.In this issue, researchers from Harvard University led by Sarah E. Henrickson conclude that human activities are contributing to illnesses associated with marine recreation [EHP 109:645-650].The team also suggests ways to reduce the incidence of illness by both monitoring pathogens to prevent human exposure and correcting environmental conditions that boost pathogen concentrations in marine waters.Marine pollution is increasing: up to 90% of untreated sewage from urban areas in developing nations is dumped into oceans and streams, and high nitrogen loads from agricultural runoff and other types of pollution may upset the ecological balances that normally keep pathogens in check.Warming oceans and extreme weather events also contribute to the growth of algal blooms that can harbor pathogens.Research reviewed by the Harvard team suggests that bacterial pathogens can survive in salt water, especially in waters with low salt concentrations (such as those found in estuaries) or high nitrogen loads.For example, marine species of Vibrio bacteria have been linked to disease in swimmers, including cases of gangrene and endometritis.Outbreaks of noninfectious disease are also of concern.These include various types of "swimmer's itch" caused by marine larvae, and neurologic symptoms from exposure to algal toxins.Swimmers can be exposed to pathogens through broken and unbroken skin.Exposure to algal toxins can also occur through the lungs when the toxins are aerosolized by heavy surf.Although public health authorities most often test for bacterial contamination, the authors' review of 131 articles suggests that the primary health hazard in coastal waters may not, in fact, be bacterial exposure, but viral instead.The authors examine, for example, one randomized controlled trial of swimming exposure conducted in the United Kingdom in which swimmers became ill even on days when concentrations of fecal coliform bacteria were at acceptable levels.
Acquired immunodeficiency syndrome in New York City. Evaluation of an active surveillance system
Authors: M. E. Chamberland
Journal: JAMA (1985)

In January 1983, the New York City Department of Health initiated an active surveillance program for acquired immunodeficiency syndrome (AIDS) in 19 hospitals and a modified-active surveillance program in the remaining 69 hospitals. We reviewed hospital laboratory and autopsy records in 12 active surveillance hospitals and three modified-active surveillance hospitals six months later. Patients who had opportunistic diseases characteristic of AIDS diagnosed in 1982 (before active surveillance) and 1983 (after implementation of active surveillance) were matched against health department AIDS surveillance reports. For the 16 months we evaluated, 96% of patients identified with AIDS in the 12 active surveillance hospitals and 100% of those in the three modified-active surveillance hospitals had been reported to the health department. The delay between diagnosing a case and reporting it to the health department significantly decreased between 1981 and the first six months of 1983 in all hospitals. The proportion of cases reported within one month of diagnosis increased from 45% to 69% during this period. We conclude that the current surveillance program for AIDS in New York City is effective and that case reporting is sufficiently complete for accurate analysis of disease trends. (<i>JAMA</i>1985;254:383-387)
Use of Haploid Plants as Bioassays for Mutagens
Authors: M. L. Christianson, M. O. Chiscon
Journal: Environmental Health Perspectives (1978)

Results of a pilot program show that suspension cultured polyhaploid Nicotiana tabacum cells can be used to bioassay the effects of mutagens.Reproducible survival curves with significant regression coeffi- cients are obtained.Putative mutation conferring resistance to amino acid analogs is significantly more frequent after exposure to mutagens; in contrast, habituants, cytokinin-independent clones, are signifi- cantly less frequent (although the variance of clone size increases!).The maximum spontaneous mutation rate is estimated at 3 x 10-8; the equilibrium frequency of habituant cells in an otherwise nonhabituated culture is estimated at 5 x 10-7.An evaluation of the system suggests changes in several and further characterization of other of the parameters involved.The use of haploid tobacco as an in vivo mutagen screen is briefly described, as is the importance of similar in vivo diploid systems for discriminating between various kinds of mutational processes.
Cimetidine therapy in Zollinger-Ellison syndrome
Authors: J. L. Orchard
Journal: JAMA (1977)

THE ZOLLINGER-ELLISON syndrome is associated with hypersecretion of gastric acid, usually owing to gastrin-secreting pancreatic tumors. Hemorrhage or perforation are complications of the malignant peptic ulcer diathesis. The recommended treatment is total gastrectomy. This case of Zollinger-Ellison syndrome is reported to illustrate an alternative treatment for patients unable to tolerate total gastrectomy. <h3>Report of a Case</h3> A 72-year-old man underwent gastroenterostomy and vagotomy in 1972 for a bleeding duodenal peptic ulcer. Intermittent episodes of epigastric pain for the next four years were treated with antacids. He was admitted on May 17, 1976, with epigastric pain, weakness, and melena, but no diarrhea; hemoglobin level was 6 gm/dl. A large duodenal ulcer was demonstrated radiographically. The basal acid output was 17 mEq/hr, and maximal acid output was 35 mEq/hr. Fasting serum gastrin level was 433 and 600 pg/ml on two occasions (normal, less than 170 pg/ml. Following a bolus of secretin (2
SEPTICEMIA
Authors: JOHN A.  KOLMER
Journal: Annals of Internal Medicine (1934)

Article1 November 1934SEPTICEMIAJOHN A. KOLMER, M.D., F.A.C.P.JOHN A. KOLMER, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-8-5-612 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptDefinition. While the condition septicemia is well understood clinically yet it is hard to define in a clear and concise manner; hence many definitions have been offered. It is characterized by pronounced signs and symptoms of infection due largely to the presence of pathogenic organisms and their products in the blood and is usually associated with infection of the fixed tissues. In my opinion it is best defined as an infection of the blood because this phase greatly predominates in the clinical manifestations.Emphasis is placed uponinfectionof the blood with all it implies as differentiated from invasion of... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Philadelphia, Pennsylvania*Trimble lecture before the Medical and Chirurgical Faculty of Maryland, April 24, 1934. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byEscherichia coli bacteremiaFifteen years' experience with staphylococcus septicemia in a large city hospitalSTAPHYLOCOCCAL BACTEREMIA 1 November 1934Volume 8, Issue 5Page: 612-631KeywordsBloodPathogensSepsisSigns and symptoms ePublished: 1 December 2008 Issue Published: 1 November 1934 PDF downloadLoading ...