tbuckley/cabot-search huggingface dataset:
The cost of coronary bypass procedures
Authors: W. S. Stoney
Journal: JAMA (1978)

We reviewed the financial records of 200 successive patients who had coronary artery bypass surgery in the first three months of 1976. The average hospital bill was $7,690 and the average length of stay was 18 days. The highest bill was $28,329 (79 days) and the lowest was $6,126 (11 days). The average total physician charge to the patient was $3,240. The total average hospital and physician cost was $10,930. (<i>JAMA</i>240:2278-2280, 1978)
APPLE News
Journal: Liver Cancer (2021)

AimsPrimary liver cancer is an extremely malignant disease, and 80% of patients are found in Asian countries.e APPLE Meetings have been initiated to provide a platform for regional and international experts to exchange information on the latest advancements in primary liver cancer treatment.e meetings are aimed at bridging gaps in the basic science and clinical aspects of liver cancer among specialists, with the ultimate aim of disseminating the results of laboratory research and clinical trials in liver cancer among professionals. Histor ye APPLE Meetings take place annually and have been hosted on rotation by the Korean Liver Cancer Study Group, the Liver Cancer Study Group of Japan, and the Chinese Liver Cancer Study Group.e 1st meeting of the group took place in Incheon in 2010, the 2nd in Osaka in 2011, the 3rd in Shanghai in 2012, and the 4th in Busan in 2013.In 2014, APPLE changed its policy and decided to expand its congress venues from three countries to include all Asian countries, and the 5th APPLE Meeting was held in Taipei in 2014.e 6th APPLE Meeting was held in Osaka in 2015, the 7th in Hong Kong in 2016, the 8th in Singapore in 2017, the 9th in Seoul in 2018, and the 10th in Sapporo in 2019.
Neurology
Authors: William K. Jordan, H. Houston Merritt
Journal: New England Journal of Medicine (1959)

WE have attempted to select for discussion, from the the many papers bearing on neurologic problems that have appeared since our last review, studies that increase understanding of the normal structure and function of the nervous system or make clearer the pathological chemistry and physiology of neurologic disorders. We have also reviewed papers concerned with symptomatology of primary neurologic diseases, as well as those describing new procedures of value in diagnosis and therapy of neurologic diseases. With the almost exponential increase in volume of neurologic literature, selection has, of course, been difficult, and many important studies have of necessity been . . .
Gastric Secretion During a Medical Interview
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE BORDERLAND IN MEDICAL LIBRARIES.
Journal: JAMA (2007)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
PRESENT KNOWLEDGE OF BRONCHIAL ASTHMA
Journal: JAMA (1927)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Osteopathic Physicians
Authors: ROBERT G. GARMON
Journal: Annals of Internal Medicine (1980)

Letters and Corrections1 August 1980Osteopathic PhysiciansROBERT G. GARMON, D.O.ROBERT G. GARMON, D.O.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-93-2-381_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: The recent article by Lohr and Brook (1) is appalling for the completely inadequate experimental design it reports and the blatant bias against osteopathic physicians. To publish the article under the guise of "academia and clinic" is an extreme irony. The comparison of M.D.s and D.O.s based on total episodes of respiratory illness without regard to the specific numbers and categories of M.D.s and D.O.s is little short of libelous. The total number of D.O.s involved in the study and the relative percentage of those indicted by the article as having made inappropriate therapeutic decisions are not...Reference1. LOHRBROOK KR. Quality of care in episodes of respiratory illness among Medicaid patients in New Mexico. Ann Intern Med. 1980;92:99-106. LinkGoogle Scholar1. LOHRBROOKKAUFMAN KRM. Quality of care in the New Mexico Medicaid program (1971-1975): the effect of the New Mexico Experimental Medical Care Review Organization on the use of antibiotics for common infectious diseases. Med Care. 1980; 18(1, suppl): 1-129. Google Scholar2. BROOKWILLIAMS RK. Evaluation of the New Mexico peer review system—1971 to 1973. Med Care. 1976;14(12, suppl):1-122. MedlineGoogle Scholar3. BROOKWILLIAMS RK. Effect of medical care review on the use of injections: a study of the New Mexico Experimental Medical Care Review Organization. Ann Intern Med. 1976;85:509-15. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Texas College of Osteopathic Medicine Fort Worth, TX 76107 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 August 1980Volume 93, Issue 2Page: 381-381KeywordsPulmonary diseasesResearch design Issue Published: 1 August 1980 PDF downloadLoading ...
Cancer Research—It Moves Ahead As Scientists Report Across Nation
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Meningococcemia diagnosed by peripheral blood smear
Authors: E. J. Young
Journal: JAMA (1988)

A college student in previous good health presented with recent onset of fever, rigors, headache, and nuchal rigidity. A routine peripheral blood smear showed many intraleukocytic and extracellular cocci and diplococci (Figure). The organisms appeared purple in the Wright-stained preparation, but the presence of a high-grade bacteremia was unmistakable. The diagnosis of meningococcemia was confirmed by a lumbar puncture, which revealed gram-negative diplococci, and later<i>Neisseria meningitidis</i>group B was grown from both cerebrospinal fluid and blood. Microorganisms are infrequently visualized in peripheral blood films,<sup>1</sup>although it has been reported that examination of the buffy-coat layer is sometimes helpful in making an early diagnosis of septicemia.<sup>2</sup>In most instances only rare organisms are seen within phagocytic cells of the buffy coat, but their presence is strong evidence of bacteremia (or fungemia). When large numbers of organisms are present, it is important to rule out pseudobacteremia caused by contaminated
Tuberculosis
Authors: Joseph D. Wassersug
Journal: New England Journal of Medicine (1949)

IT IS well nigh impossible for a single reviewer to encompass the entire field of tuberculosis, so vast are its ramifications. In a review such as this, one is forced to limit himself to the highlights of the year, and, even then, some significant contributions may be overlooked or touched upon only lightly.The fact that tuberculosis mortality continues to show a gratifying decline cannot be overlooked. The death rate for tuberculosis, with few interruptions, has shown a continuous decline since 1910. In 1946, it was only 36.4 per 100,000 population,1 which amounted to a 9.2 per cent decrease from . . .
Effects of interleukin (IL)-3 and IL-5 on human eosinophil degranulation induced by complement components C3a and C5a
Authors: S. Takafuji, K. Tadokoro, K. Ito
Journal: Allergy (1996)

It is suggested that eosinophils (Eos) play an important role in the pathogenesis of bronchial asthma by releasing cytotoxic cationic eosinophil granule proteins and damaging bronchial epithelial cells. However, the exact nature of the actual inducer of eosinophil degranulation in vivo is unclear. We examined eosinophil cationic protein (ECP) release from human Eos in response to soluble agonists such as C5a, C3a, platelet-activating factor, and FMLP with or without interleukin (IL)-3 or IL-5 priming. Eosinophil degranulation induced by these soluble agonists required the pretreatment of Eos by cytochalasin B even in IL-3 priming. Among four agonists, C5a was the most effective stimulus of ECP release either with or without IL-5 priming. IL-3 and IL-5 remarkably enhanced ECP release in Eos triggered by C3a and C5a. The enhancement of ECP release by IL-3 and IL-5 occurred at 0.1–0.3 ng/ml and became maximal at 10–30 ng/ml, concentration-dependently. The enhancement of ECP release by cytokines became optimal at an interval of 10 min. Our data support the importance of complement components and cytokines in eosinophil degranulation in vivo.
Availability of Diabetes Information on the Internet
Journal: JAMA (1997)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Death enlightened. A study of Frederik Ruysch
Authors: A. M. Luyendijk-Elshout
Journal: JAMA (1970)

Man never ceases to confront the mystery of death. According to the particular cultural pattern, Death may represent a merciless enemy or a welcome friend—a grinning skeleton wielding his scythe or, wrapped in a long cloak, a serene attendant waiting patiently at the bedside of the dying. Today, as our medical knowledge increases, Western man has to a great extent lost contact with death as a daily reality. The borderline between life and death is continually pushed back, and becomes less and less sharp. Death is in discredit, and we even tend to deny its inevitability. Belief in the hereafter, in a better life to come as a reward for the suffering of this world, are concepts disappearing from Western thought. Not so in the 17th century, when Death was everywhere a familiar and daily guest. Epidemics raged, life expectancy was short and child mortality was high. Therapeutic resources were
The treatment of pulmonary edema in the absence of renal function. A role for sorbitol and furosemide
Authors: C. C. Anderson
Journal: JAMA (1979)

In doses sufficient to induce a rapid osmotic loss of fluid from the bowel, sorbitol can provide an alternate method of removing fluid in patients who lack renal function. Two patients with acute pulmonary edema and oliguric renal failure were treated with a combined therapy of sorbitol and furosemide. Their clinical, hemodynamic, and metabolic responses were strikingly similar to those achieved with furosemide therapy alone in patients with normal renal function. (<i>JAMA</i>241:1008-1010, 1979)
Erratum to: Case Report: Adrenal LH/hCG Receptor Overexpression and Gene Amplification Causing Pregnancy-Induced Cushing’s Syndrome
Authors: Michael Herman Chui, Nese Colak Özbey, Shereen Ezzat, Yersu Kapran, Yesim Erbil, Sylvia L. Asa
Journal: Endocrine Pathology (2009)
Progress Toward Poliomyelitis Eradication-South East Asia Region, 1988-1994
Journal: JAMA (1995)

In 1988, the World Health Assembly resolved to eradicate poliomyelitis by 2000. To achieve this goal, in 1994 World Health Organization (WHO) South East Asia Region (SEAR) member countries accelerated implementation of polio eradication strategies. In 1994, Thailand became the region's first country to initiate National Immunization Days (NIDs), followed by Bangladesh, Bhutan, India, Indonesia, and Sri Lanka (1995); Myanmar and Nepal (1996); and Democratic People's Republic (DPR) of Korea and Maldives (1997). This report summarizes the progress in achieving routine and supplemental vaccination coverage and surveillance for cases of acute flaccid paralysis (AFP) and the impact of these activities on polio eradication in the region.
Half of Perforated Ulcers Found Sealed at Admission
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Psychiatrische Untersuchungen an einer Serie von Zwillingen
Journal: JAMA (1942)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE NATURE OF PUERPERAL ECLAMPSIA.
Journal: JAMA (1905)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Color Yet
Authors: J. Andrew Talbeau
Journal: JAMA (1961)

<h3>To the Editor:—</h3> Once more I take it upon myself as a representative of the literary world to comment upon your journal. It seems that you are really intent on making progress. And you are to be complimented. Volume 175, No. 1, has just arrived and it was with eager anticipation that I opened the nowbrilliant covers. And what wonders therein. To those not "formatly-oriented," perhaps nothing was striking. But to those who look as well as read, the changes were pleasing and well done. The new headings for<i>Letters</i>and<i>References &amp; Reviews</i>are tasteful and provide a change from the former drab, grey neutralness of the<i>JAMA</i>. The effect of subheads in<i>Questions and Answers</i>, a small thing, but also well executed, is fluid, soft and pleasing to the eye. I approve of your innovation of putting<i>Abstracts</i>on "single" pages, but feel a bit dejected that you
Cell biology: Receptors and signal transduction
Journal: Hepatology (1995)

Multidrug resistance-associated protein 2 (MRP2) (ABCC2) is an ATP-binding cassette membrane protein located primarily on apical surface of hepatocytes that mediates transport of conjugated xenobiotics and endogenous compounds into bile. MRP2 is highly expressed in hepatocytes, and at lower levels in small intestines, stomach and kidney. Previous reports have characterized mammalian MRP2 promoters, but none have established the molecular mechanism(s) involved in liver enriched expression. This study aims to investigate the mechanism of hepatic MRP2 regulation.A 2130 bp of MRP2 promoter was cloned from PAC-1 clone P108G1–7, to identify putative liver specific/hormone responsive functional DNA binding sites. Using deletion analysis, site specific mutagenesis and co-transfection studies, liver specific expression was determined.MRP2 promoter-LUC constructs were highly expressed in liver cell lines compared to non-liver cells. The region extending from − 3 to+ 458 bp of MRP2 promoter starting from AUG contained the potential binding sites for CAAATT box enhancer binding protein (C/EBP), hepatocytes nuclear factor 1, 3 and 4 (HNF1, HNF3, and HNF4. Only HNF1 and HNF4 co-transfection with MRP2 luciferase increased expression. Site specific mutational analysis of HNF1 binding site indicated an important role for HNF1α. HNF4α induction of MRP2 was independent of HNF1 binding site. C/EBP, HNF3, and HNF6 inhibited HNF1α while HNF4α induced MRP2 luciferase expression and glucocorticoids stimulated MRP2 expression.This study emphasizes the complex regulation of MRP2 with HNF1α and HNF4α playing a central role. The coordinated regulation of xenobiotic transporters and oxidative conjugation may determine the adaptive responses to cellular detoxification processes.