tbuckley/cabot-search huggingface dataset:
A Manual of Nursing in Pelvic Surgery.
Journal: JAMA (1894)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Stroke: Pathophysiology, Diagnosis, and Management
Authors: Jonathan H. Pincus
Journal: JAMA (1994)

At a time of striking advances in physiological understanding, increased diagnostic accuracy, and effective therapies for both prevention of stroke and reduction of brain damage after stroke, there is increased need for a textbook that deals with this entity. In the past, the major issues addressed in textbooks concerned how to identify the location of a lesion within the brain and how to differentiate occlusion and hemorrhage. The body of knowledge moved at a glacial pace. The fact that there is a need for this, the second edi
Other Books
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Expression of the rat liver Na+/taurocholate cotransporter is regulated in vivo by retention of biliary constituents but not their depletion
Authors: C Gartung
Journal: Hepatology (1997)

Expression and function of the hepatic Na+/taurocholate cotransporter (ntcp) are down-regulated in several models of experimental cholestasis. To test whether retention and/or depletion of biliary constituents are involved in ntcp regulation, ntcp expression was quantified in several animal models with altered levels of these constituents. In choledochocaval fistula rats (CCF) (retention model), ntcp mRNA expression specifically declined after 1 and 3 days by 76 +/- 4% (P < .005) and 31 +/- 9% (P < .05), respectively, returning to control levels by 7 days. However, protein expression as assessed by Western blotting remained unchanged for up to 7 days of CCF. In rats with bile fistulas (depletion model) for 0.5, 1, 2, 4, and 7 days, both ntcp protein and mRNA expression remained unaltered. Infusion of either taurocholate or taurochenodeoxycholate for 12 hours also did not effect ntcp mRNA expression in intact animals, probably because of its inability to increase serum and intrahepatic bile acid levels. In rats with selective bile duct ligation (SBDL), ntcp mRNA levels were down-regulated by 40 +/- 10% (P < .05) only after 12 and 24 hours in ligated lobes, and mRNA levels returned to control values in these lobes after 2 and 4 days. ntcp mRNA expression remained unchanged in the nonobstructed lobes at any time. When data from CCF and SBDL rats were combined, serum bile acids correlated linearly with ntcp mRNA (r = .62, P < .0005) over a 0 to 110-micromol/L range. Our results indicate that ntcp is constitutively expressed and remains uneffected by either depletion or increased flux of biliary constituents. However, retention of biliary constituents results in rapid down-regulation of ntcp mRNA, consistent with the concept that hepatocytes may be protected from bile acid toxicity during cholestasis by this mechanism. (Hepatology 1997 Feb;25(2):284-90)
Rubella Before Conception as a Cause of Fetal Abnormality
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Holistic Medicine
Authors: C. Norman Shealy
Journal: JAMA (1979)

<h3>To the Editor.—</h3> In response to the editorial by John P. Callan, MD, I want to say that in general, his concern is the same as that of most physicians who have joined the American Holistic Medical Association. The name "holism" is important primarily because of its basic philosophy: "The whole is greater than the sum of the parts." Those of us who believe that the concept of holism is in need of active encouragement in our society emphasize certain basic principles: a thorough medical history, including social stress evaluation, proper physical diagnosis by a physician, and appropriate laboratory tests, which may include evaluations of blood, urine, and hair, in addition to roentgenographic examinations and other special procedures. For a majority of patients who see physicians, the diagnosis at that point is likely to be some form of psychosomatic or stress disorder. In an editorial in the<i>New England Journal</i>
The relationship between the thrombotic and infectious complications of central venous catheters
Authors: I. I. Raad
Journal: JAMA (1994)

<h3>Objectives.</h3> —To assess the frequency of thrombotic and infectious complications of long-term use of vascular catheters in cancer patients and to determine whether the two types of complication are related. <h3>Design.</h3> —Case series. <h3>Setting.</h3> —A 500-bed tertiary cancer center. <h3>Patients.</h3> —Seventy-two cancer patients. <h3>Interventions.</h3> —During a 16-month period, postmortem examinations of catheterized veins and contralateral uncatheterized veins were done on all patients with indwelling central venous catheters who met study criteria. <h3>Main Outcome Measures.</h3> —Catheter-related septicemia determined by clinical and microbiological data as well as postmortem pathology; venous pathological changes such as mural hemorrhage, thrombosis, calcification, ulceration, and inflammation. <h3>Results.</h3> —Premortem clinical and microbiological data were obtained retrospectively on all patients. Pathological changes were noted in 35 catheterized veins (49%) compared with five contralateral control veins (9.2%) (<i>P</i>&lt;.001). Mural thrombi were noted in 27 catheterized veins (38%) compared with only one contralateral control vein (1.4%) (<i>P</i>&lt;.001). Other pathological changes consisted of four central venous catheter—related mural thrombi (5.6%) in the right atrium and four instances (5.6%) of nonbacterial thrombotic endocarditis, three involving the tricuspid and one the mitral valves. Seven patients had catheter-related septicemia. Of the 31 patients with mural thrombosis of the catheterized vein or right atrium, seven developed catheter-related septicemia, whereas none of the 41 patients with normal catheterized veins and atria developed catheter-related septicemia (<i>P</i>&lt;.01). <h3>Conclusions.</h3> —Thrombotic complications are common in catheterized veins and are often associated with catheter sepsis. (<i>JAMA</i>. 1994;271:1014-1016)
Menstrual extraction. Putting it and all its synonyms into proper perspective as pseudonyms
Authors: J. E. Hodgson
Journal: JAMA (1974)

BEFORE the US Supreme Court decision which legalized abortion on Jan 22, 1973, the performing of uterine evacuations before pregnancy could be diagnosed was suggested as a way of evading abortion laws.<sup>1</sup>Some advocates argued that women did not really want to know whether they had terminated a pregnancy or not. If no examination of tissue was performed, both doctor and patient could be ignorant of the diagnosis. No one seemed concerned regarding the possibility of overlooking an ectopic pregnancy, hydatidiform mole, or an endocrine dysfunction. Articles on the subject appeared in one account (<i>Newsweek</i>, July 24, 1972, p 69), in Johnston's account (<i>New York Times</i>, Nov 19, 1972), and other newspapers, evoking much interest from the public. While the medical world was pondering the merits of this philosophy, women's liberation groups pounced on the concept of menstrual extraction, viewing it as a means of better controlling their own destinies and
Isolation of Respiratory Syncytial Virus from Children with Acute Respiratory Disease
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
AIDS
Journal: JAMA (1999)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Coronary Care
Journal: JAMA (1970)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Increased Cholecystectomy Rate After Introduction of Laparoscopic Cholecystectomy-Reply
Authors: Antonio P. Legorreta
Journal: JAMA (1994)

<h3>In Reply.</h3> —We appreciate the comments of Foster et al and definitely agree with them that one should be careful not to generalize results when using a "relatively small convenience sample"; however, we do not think that a private practice— based HMO having 500 000 enrollees is a small sample. The national estimated rates reported in the 1991 NHDS were based on a medical record survey sample.<sup>1</sup>In our study, we used a complete sample of US Healthcare's HMO enrollees in southeastern Pennsylvania. Although it is possible that the increase in the cholecystectomy rate might have been an isolated phenomenon related only to the population that we studied—as suggested by Foster et al—there is much evidence to suggest otherwise. Orlando et al<sup>2</sup>documented a 29% increase in cholecystectomies in the state of Connecticut after the introduction of the laparoscopic approach. Drs Klar and Kongstvedt report a 52.4% increase
Increased Amygdala and Insula Activation During Emotion Processing in Anxiety-Prone Subjects
Authors: Murray Stein
Journal: American Journal of Psychiatry (2007)

Objective: Increased amygdala reactivity during processing of certain types of emotional stimuli (e.g., fear, anger) has been observed in patients with anxiety disorders such as social phobia and posttraumatic stress disorder (PTSD). It is uncertain whether this heightened amygdala reactivity is specific to treatment-seeking patients with anxiety disorders or is a general feature of individuals with increased anxiety-related temperamental traits. Method: Thirty-two physically healthy subjects 18–21 years old were recruited from a large pool of college students. Of these, 16 were chosen on the basis of scoring in the upper-15th percentile on a measure of trait anxiety (anxiety-prone group), and 16 were chosen on the basis of scoring in the normative range (40th–60th percentile). Subjects participated in functional magnetic resonance imaging (fMRI) during an emotion face assessment task that has been shown to reliably engage amygdala and associated limbic structures. Results: Anxiety-prone subjects had significantly greater bilateral amygdala and insula activation to emotional faces than did the anxiety-normative comparison subjects. Higher scores on several measures assessing anxiety proneness (e.g., neuroticism, trait anxiety, and anxiety sensitivity) were associated with greater activation of the amygdala (predominantly left-sided) and the anterior insula (bilateral). Conclusions: Increased amygdala and insula reactivity to certain types of emotional processing is seen in young adults with increased anxiety-related temperamental traits. Therefore, this brain emotion-processing profile may be a functional endophenotype for proneness to (certain kinds of) anxiety disorders.
Prostaglandins research captures Nobel prize
Authors: W. A. Check
Journal: JAMA (1982)

The 1982 Nobel Prize in Physiology or Medicine was awarded Oct 11 to three researchers instrumental in both the discovery of the family of chemical messengers called prostaglandins and the unraveling of the functions of these natural substances. The award was given jointly to Sune K. Bergstrom, MD, PhD, 66, and Bengt I. Samuelsson, MD, 48, both of the Karolinska Institute, Stockholm, and John R. Vane, DSc, 55, director of research at the Wellcome Research Foundation in Beckenham, England. In an interview with<i>JAMA</i>MEDICAL NEWS, Bergstrom emphasized the importance of the prostaglandin system by noting that "prostaglandins are synthesized in all nucleated cells in the body and can influence the functioning of any type of cell. They [constitute] a general regulatory mechanism for mammalian physiology." This year's Nobel honors again show the predictive power of the comparable American prize, the Albert Lasker medical research award. In 1977, the same
TURNBUCKLE EXTENSION APPARATUS FOR THE REDUCTION OF FRACTURES
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Health-Related Quality of Life Among Adults With Arthritis—Behavioral Risk Factor Surveillance System, 11 States, 1996-1998
Journal: JAMA (2000)

Arthritis and other rheumatic conditions are the leading cause of disability in the United States, affecting 43 million persons in 1998 and-with the aging of the "baby boom" generation-are projected to affect an estimated 60 million by 2020. In 1992, these conditions cost $65 billion in medical care and lost productivity and were associated with 744,000 hospitalizations and 44 million ambulatory-care visits in 1997. Because arthritis and other rheumatic conditions seldom cause death but have a substantial impact on health, health-related quality of life (HRQOL) measures are better indicators of their impact than related mortality rates. This report examines data from 11 states that included an arthritis module in the 1996-1998 Behavioral Risk Factor Surveillance System (BRFSS); findings indicate that persons with arthritis have worse HRQOL than persons without arthritis, regardless of sex, age, or education level.
Authors' Reply
Authors: Jeffrey R Lacasse, Jonathan Leo
Journal: PLoS Medicine (2006)

I would like to thank PLoS Medicine for publishing Lacasse and Leo's important and methodical Essay that debunks the "chemical imbalance" advertisements for psychiatric drugs [1].Why would the United States Food and Drug Administration (FDA) approve such ads?Our human rights group, MindFreedom International, has been asking that question for a long time.On behalf of MindFreedom, US Senator Ron Wyden contacted the FDA for an explanation about why they approve such advertising.In their responsewhich took over one year to receive-the FDA could cite no scientifi c literature or studies.It turns out there's a good reason that the FDA can't fi nd any scientifi c evidence for the claims of a "chemical imbalance" in these ads: the scientifi c evidence in support of the serotonin hypothesis is very weak.Readers who would like more information about the psychiatric industry's advertising suggesting a "chemical imbalance" in depression may be interested in the following:(1) MindFreedom's debate with Pfi zer, manufacturer of Zoloft, available at http:⁄⁄www.mindfreedom.org/mindfreedom/pfi zerlies.shtml,and (2) a historic debate with the American Psychiatric Association resulting from MindFreedom's 2003 hunger strike, available at http:⁄⁄www.mindfreedom.org/mindfreedom/hungerstrike.shtml
Snowmobile Injuries
Authors: Stanley E. Chism
Journal: JAMA (1969)

The recreational use of snowmobiles has increased at a phenomenal rate. The large number of injuries resulting from their operation prompted this preliminary study to determine the mechanism and types of injuries incurred. Often the type of injury can be correlated with the mechanics of snowmobile construction and operation. For example, compression fractures of vetebrae appear to result from inability of the spine to absorb the shock of traveling over irregular terrain. Most fractures, bruises, and lacerations result from faulty operation of the vehicles.
THE BRITISH GYNECOLOGICAL SOCIETY Refuses ADMISSION TO WOMEN.
Journal: JAMA (1893)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal