tbuckley/cabot-search huggingface dataset:
Minocycline-induced Pneumonia
Authors: Allan J. Bridges
Journal: Annals of Internal Medicine (1993)

Letters1 May 1993Minocycline-induced PneumoniaAllan J. Bridges, MDAllan J. Bridges, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-118-9-199305010-00028 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:We have reported a case [1] of minocycline-induced pneumonitis similar to that reported by Guillon and colleagues [2]. After 4 months of minocycline therapy for acne, a young woman developed bilateral pulmonary infiltrates and fever. Bronchoalveolar lavage specimens obtained while the patient continued minocycline therapy showed macrophages, 31%; neutrophils, 60%; eosinophils, 5%; and bronchial epithelial cells, 4%; with a total cell count of 2000. We did not find evidence of bronchoalveolar lavage lymphocytosis. Flow cytometry was not done.Within 2 weeks of discontinuing minocycline therapy, the symptoms and infiltrates resolved. Simultaneously, the patient developed erythema nodosum.It ...References1. Bridges AJ, Graziano FM, Calhoun W, Reizner GT. Hyperpigmentation, neutrophilic alveolitis, and erythema nodosum resulting from minocycline. J Am Acad Dermatol. 1990; 22:959-62. Google Scholar2. Guillon JM, Joly P, Autran B, Denis M, Akoun G, Debre P, et al. Minocycline-induced cell-mediated hypersensitivity pneumonitis. Ann Intern Med. 1992; 117:476-81. Google Scholar3. Valcke Y, Pauwels R, Van Der Straeten M. Bronchoalveolar lavage in active hypersensitivity pneumonitis caused by sulfasalazine. Chest. 1987; 92:572-3. Google Scholar4. Gall JM, Villanova JL, Mayos M. Febarbamate-induced pulmonary eosinophilia: a case report. Respiration. 1986; 49:231-4. Google Scholar Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited BySafety of doxycycline and minocycline: A systematic reviewMinocycline-Induced Pericardial EffusionDrug-induced pseudolymphoma and drug hypersensitivity syndrome (drug rash with eosinophilia and systemic symptoms: DRESS)Drug-induced pulmonary disease 1 May 1993Volume 118, Issue 9Page: 749-750KeywordsBronchoalveolar lavageEpithelial cellsFlow cytometryHypersensitivityHyperthermiaImmune responseLungsNeutrophilsPneumoniaPneumonitis Issue Published: 1 May 1993 CopyrightCopyright © 1993 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...
Incorrect Dose
Journal: JAMA (1976)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
American Review of Respiratory Diseases, New York
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
From the Food and Drug Administration
Authors: S. L. Nightingale
Journal: JAMA (1991)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Terbutaline and maternal cardiac function
Authors: J. M. Wagner
Journal: JAMA (1981)

The effect of terbutaline sulfate on left ventricular size and performance was studied by M-mode echocardiography in pregnant women with premature labor. Patients with uterine activity initiated during either oxytocin challenge testing or induction of labor served as a comparison group. During terbutaline therapy, heart rate, ejection fraction, and cardiac output increased significantly. End-diastolic volume and systolic blood pressure (BP) were unchanged, and diastolic BP and end-systolic volume fell. No changes in echocardiographic or hemodynamic parameters were present during oxytocin-induced uterine activity. Terbutaline, as currently used to prevent premature labor, is a potent inotropic and chronotropic agent. Pulmonary edema accompanying terbutaline treatment is probably not due to cardiac failure. (<i>JAMA</i>1981;246:2697-2701)
Government Services
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Glucocorticoid Resistance
Authors: Christoph M. Bamberger
Journal: Annals of Internal Medicine (1994)

Letters15 June 1994Glucocorticoid ResistanceChristoph M. Bamberger, MD and George Chrousos, MDChristoph M. Bamberger, MDDepartment of Health and Human Services; National Institutes of Health; Bethesda, MD 20892Search for more papers by this author and George Chrousos, MDDepartment of Health and Human Services; National Institutes of Health; Bethesda, MD 20892Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-120-12-199406150-00017 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:We wish to add our perspective to the issue of a putative inhibitory variant of the human glucocorticoid receptor raised by Dr. Lazar. Sequence analysis of the human glucocorticoid receptor cDNAs [1] and gene [2] showed two alternative splicing products that led to expression of two isoforms: the classic receptor, termed glucocorticoid receptor α, and a highly homologous, non-ligand-binding, presumably nontransactivating protein glucocorticoid receptor β [1, 3, 4]. To examine a possible analogy to the case of the α 2 triiodothyronine receptor [5], we studied the function of the β isoform in glucocorticoid receptor α and β cotransfection ...References1. Hollenberg SM, Weinberger C, Ong ES, Cerelli G, Oro A, Lebo R, et al. Primary structure and expression of a functional human glucocorticoid receptor cDNA. Nature. 1985; 318:635-41. Google Scholar2. Encio IJ, Detera-Wadleigh SD. The genomic structure of the human glucocorticoid receptor. J Biol Chem. 1991; 266:7182-8. Google Scholar3. Karl M, Lamberts SW, Detera-Wadleigh SD, Encio JE, Stratakis CA, Hurley DM, et al. Familial glucocorticoid resistance caused by a splice site deletion in the human glucocorticoid receptor gene. J Clin Endocrinol Metab. 1993; 76:683-9. Google Scholar4. Chrousos GP, Detera-Wadleigh SD, Karl M. Syndromes of glucocorticoid resistance. Ann Intern Med. 1993; 119:1113-24. Google Scholar5. Lazar MA, Hodin RA, Chin WW. Human carboxy-terminal variant of α-type c-erbA inhibits transactivation by thyroid hormone receptors without binding thyroid hormone. Proc Natl Acad Sci U S A. 1989; 86:7771-4. Google Scholar Author, Article, and Disclosure InformationAuthors: Christoph M. Bamberger, MD; George Chrousos, MDAffiliations: Department of Health and Human Services; National Institutes of Health; Bethesda, MD 20892 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byTheoretischer Bezugsrahmen, Konzeptionalisierung der Konstrukte und ModellentwicklungTheoretische Grundlagen der Zusammenschlussform „Unternehmungsakquisition“ 15 June 1994Volume 120, Issue 12Page: 1047-1048KeywordsComplementary DNAProteinsSequence analysisTriiodothyronine ePublished: 15 August 2000 Issue Published: 15 June 1994 Copyright & PermissionsCopyright © 1994 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Le Vieillissement Artificiel des Vins et Spiritueux.
Journal: JAMA (1906)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Genetic Engineering
Authors: John L. Kuehn
Journal: JAMA (1972)

<h3>To the Editor.—</h3> Having just finished reading Dr. Ramsey's elegant and articulate discourse, I am troubled by a quote (from Edwards and Sharpe) from which much of his argument arises: The desire to have children must be among the most basic human instincts and denying it can lead to considerable psychological and social difficulties. My clinical experience in counseling engaged or recently married young adults differs from what this quote implies. To<i>have</i>children is probably a basic drive, particularly among women, but there is no parallel drive to<i>care for and educate</i>children. I believe these aspects in the humanization of biological man are for the most part learned. While Dr. Ramsey pleads for consideration of the "natural piety" of man by defense of in vivo procreation, he does not deal with the more troubling issue. What are the implications of his arguments for child-rearing in such a way
MISCELLANY.
Journal: JAMA (1893)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Architecture of the Brain.
Journal: JAMA (1897)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
This Week in &lt;EMPH&gt;JAMA&lt;/EMPH&gt;
Journal: JAMA (2006)

A Piece of My Mind"The people in this area do not have many options for medical care.Their community is rife with hunger, poverty, malnutrition, and high infant mortality."From "Duffle Bag Medicine." SEE PAGE 1491 Medical News & PerspectivesThe performance of the nation's first fully equipped mobile surgical hospital, deployed to aid survivors of Hurricane Katrina, raises new questions about hospital surge capacity in the event of future disasters.
Malpractice Laws
Authors: Glenn W. Dopf
Journal: JAMA (1972)

<h3>To the Editor.—</h3> Upon reading a MEDICAL NEWS article inThe Journal(220:184, 1972) entitled "Physicians Alerted to Newest Developments in Malpractice Laws," I was most disappointed. The malpractice problem is too complex to be explained in generalities as the news article did. I have recently completed a research project entitled "The Physicians Guide to Medical Malpractice." This guide was constructed to fulfill a college research requirement and, consequently, will not be published. While interviewing various physicians I found most to possess only an elementary understanding of the problem. It is impossible for me to go into details at the present time, but I will include one grossly misunderstood concept that I found. It has been established in most states that a mature minor (15 years and older) can be treated without parental consent. The only stipulation is that the minor have an understanding of the consequences of the treatment,
Junior hospital doctors and Europe
Authors: P. McNally
Journal: BMJ (1976)

<b>Background:</b> Patients with pulmonary hypertension develop intimal plaques in large pulmonary arteries. <b>Objective:</b> To test the hypothesis that the composition of such plaques differs depending on whether the aetiology of the disease is thromboembolic or hypertensive. <b>Design:</b> Chronic thromboembolic and plexogenic pulmonary hypertension (primary and secondary (Eisenmenger syndrome)) were investigated. These are spontaneous human models and were used to examine the independent role of thrombus and hypertension in plaque composition. <b>Setting:</b> A national tertiary referral centre for lung transplantation and pulmonary thromboendoarterectomy. <b>Patients:</b> Thirty nine patients with chronic thromboembolic pulmonary hypertension who had undergone thromboendoarterectomy (n = 32) or lung transplantation (n = 7), 28 with plexogenic diseases (nine primary and 19 Eisenmenger), and three with Eisenmenger syndrome complicated by thromboembolic events. <b>Interventions:</b> The lung and thromboendoarterectomy samples were sectioned, stained with Movat pentachrome, and immunostained with antibodies for fibrin, platelets, inflammatory cells, smooth muscle cells, and erythrocyte membrane glycophorin A. <b>Main outcome measure:</b> Composition of the plaques affecting large pulmonary arteries. <b>Results:</b> Two types of intimal lesion were distinguished in chronic thromboembolic pulmonary hypertension: fibrous plaques with angioneogenesis; and core-rich atherosclerotic plaques with pultaceous cores largely consisting of glycophorin immunoreactive material, with cholesterol clefts (61.5%), CD68 positive macrophages (84.6%), T lymphocytes (87%), and calcification (46.1%). The samples from the patients with Eisenmenger syndrome and thromboembolic complications had similar characteristics, whereas those from patients with uncomplicated primary pulmonary hypertension had core-free fibrous plaques, spotted with macrophages and T lymphocytes. <b>Conclusions:</b> Chronic thromboembolic pulmonary hypertension is associated with atherosclerotic plaques with glycophorin-rich pultaceous cores, and plexogenic pulmonary hypertension with fibrous plaques. Thromboembolic material thus plays a critical role in the formation of pultaceous cores, of which erythrocyte membrane derived glycophorin is a major component.
Severe alkalosis during assisted ventilation in chronic obstructive pulmonary disease
Journal: JAMA (1990)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Journal of Pediatrics, St Louis
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Resuscitation and anesthetic management of casualties
Authors: D. J. Torpey
Journal: JAMA (1967)

Resuscitative efforts for the severely wounded casualties were directed toward adequate pulmonary ventilation and oxygenation, replacement of blood and extracellular fluid volumes, correction of existing acidosis, and the maintenance of adequate cardiac and renal function. Definitive surgical procedures were performed after adequate resuscitative measures had been accomplished. A light plane of general anesthesia combined with a muscle relaxant was the most satisfactory technique for the extensively injured patient. Spinal, epidural, and axillary blocks were used with relative frequency, especially in those patients having lower abdominal, genitourinary, or extremity injuries. Accurate and frequent monitoring during anesthesia and surgery was performed within the clinical means available. Application of the basic sciences to clinical medicine and the knowledge of reliable publications allowed for the up-to-date management of the battle casualties under field conditions.