tbuckley/cabot-search huggingface dataset:
Dermatology
Authors: Sharon Mitchell
Journal: JAMA (1992)

This Lange series book is surprisingly easy to read, attractively priced, an excellent reference source, and very succinct. <i>Dermatology</i>is well organized, comprehensive, and arranged in an easy-to-follow format that includes "Essentials of Diagnosis," "Clinical and Laboratory Findings," "Differential Diagnosis," and "Treatment With Prevention and Prognosis." Other important features are its numerous tables and figures, allowing for the incorporation of large amounts of information succinctly, eg, the tables "Laboratory Studies as Diagnostic Aids," "Classification of Skin Tumors," and "Diagnostic Suggestions From the Localization of Lesions." In their preface the editors state that the intended audience is broad and varied, encompassing "medical students, primary care physicians, and dermatologists, as well as other physicians, nurses, and ancillary medical personnel." With such a diverse target audience, it is predictable that selected sections may have more depth than some groups of readers would find of interest (for example, the chapters on electron microscopy and
European Perspectives
Journal: Circulation (2011)

14 years of experience in cardiovascular interventions and helped draft the European Society of Cardiology 2010 guidelines on the management of atrial fibrillation. 1He is a member of many international committees and steering groups, runs a translational research group, and coordinates controlled clinical trials, including the Early Treatment of Atrial Fibrillation for Stroke Prevention Trial (EAST) and the Flecainide Short-Long (Flec-SL) trial, 2,3 both of which are primarily funded through the German Atrial Fibrillation Network (AFNET).
Analgesic nephropathy.
Journal: BMJ (1981)

Analgesic nephropathyIs analgesic nephropathy, like smallpox, now only a part of medical history?Did the campaign to remove phenacetincontaining compound analgesic tablets from pharmacists' counters succeed in eliminating this often fatal disorder ?Thirty years ago analgesic nephropathy had not been recognised and most of its victims were diagnosed as having chronic pyelonephritis.After the initial description by Spuhler and Zollingert several larger and carefully analysed series of cases were published, and the clinical and radiological features became definedA.2-6Clinicians prepared to take a careful history from the patient and relatives and to examine urine specimens for evidence of analgesic intake made the diagnosis quite frequently.In Nottingham, a reasonably typical urban community, analgesic nephropathy was responsible for at least 12%/ of cases of severe chronic renal failure presenting between 1970 and 1975-around 10 new cases each year from each million population.6In about a third of these patients the diagnosis had been "missed" and came to light only as a result of the epidemiological survey.Statistics from the European Dialysis and Transplant Association7 on the causes of chronic renal failure receiving treatment suggest that around 301'/ are drug-induced, varying from 0 4°( in Spain to 17 50%o in Switzerland, with 1.200 given as the British figure.These differences have many causes.In addition to misclassification and geographical difference in prevalence some distortion results from the selection of patients for dialysis and trans- plantation, since those who have misused drugs often have social or psychiatric reasons making them less suitable for treatment.In Scandinavia7 and in Scotland8 recent data have suggested a drop in the number of cases, and nephrologists in England also have the impression that new patients with analgesic nephropathy are becoming less common in their clinics.These observations may be the result of phenacetin being taken out of most analgesic mixtures after representations by nephrologists during the early 1970s.Concern remains, however, that paracetamol (which was widely substituted for phenacetin) might also be nephrotoxic, especially when in compound analgesic tablets.Indeed, some nephrologists suggest that most common analgesics, even aspirin taken alone, may cause renal damage.If it occurs at all this response is rare in Britain.Some interesting questions remain after two decades of research and speculation.
From Chaucer to Darwin, Down in Kent
Authors: J. R. E.
Journal: Annals of Internal Medicine (1963)

Editorials1 February 1963From Chaucer to Darwin, Down in KentJ. R. E.J. R. E.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-58-2-369 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptWhen in April the sweet showers fall . . .Then people long to go on pilgrimages . . .And specially, from every shire's endIn England, down to Canterbury they wendTo seek the holy blissful martyr, quickTo give his help to them when they were sick.In the fourteenth century when Chaucer's pilgrims journeyed from London to Canterbury to visit the "clinic" of the sainted Thomas à Becket, they followed the heights of the North Downs in Kent. These are a long ridge of steep chalk hills in southeastern England that run from west to east...References1. EISELEY L: Darwin's Century. Evolution and the Men Who Discovered It, Doubleday and Company, Inc., New York, 1958. Google Scholar2. DARWIN C: Journal of Researches into the Geology and Natural History of the Various Countries Visited by H.M.S. Beagle. A facsimile reprint of the first edition of 1839, Hafner Publishing Company, New York-London, 1952. Google Scholar3. IRVINE W: Apes, Angels, and Victorians. The Story of Darwin, Huxley, and Evolution. McGraw-Hill Book Company, Inc., New York, 1955. Google Scholar4. HUXLEY J: The emergence of Darwinism, in The Evolution of Life, Vol. I of Evolution after Darwin, edited by Tox, S., University of Chicago Press, Chicago, 1960, pp. 1-21. [The first of three volumes reporting the Darwin Centennial Symposium held at the University of Chicago in 1959—Ed.] CrossrefGoogle Scholar5. SIMPSON GG: The world into which Darwin led us. Science 131: 966, 1960. CrossrefMedlineGoogle Scholar6. BatesHumphrey MPS The Darwin Reader, edited by , Charles Scribners Sons, New York, 1956. [An excellent annotated selection of Darwin's writings from all the books that I have mentioned—Ed.] Google Scholar7. Darwin F The Life and Letters of Charles Darwin, including an Autobiographical Chapter, edited by , Basic Books, Inc. New York, 1959, 2 volumes. Google Scholar8. RAVERAT G: Period Piece, W. W. Norton and Company, Inc., New York, 1953. Google Scholar9. ALVAREZ WC: The nature of Charles Darwin's lifelong ill-health. New Engl. J. Med. 261: 1109, 1959. CrossrefMedlineGoogle Scholar10. COLP R: Correspondence. Illness of Charles Darwin. New Engl. J. Med. 262: 421, 1960. CrossrefGoogle Scholar11. SPECTOR B: Darwin—Down House—dawn. New Engl. J. Med. 260: 1119, 1959. [Contains excellent photographs of Darwin's study—Ed.] CrossrefGoogle Scholar12. CHAUCER G: The Canterbury Tales, translated by Coghill, N., Penguin Books, Baltimore, Maryland, 1952, pp. 248-256. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 February 1963Volume 58, Issue 2Page: 369-372KeywordsFalls Issue Published: 1 February 1963 PDF downloadLoading ...
SIR WILLIAM FERGUSSON (1808-1877)— PRACTICAL SURGEON
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
James Ewing
Authors: Joseph C. Hinsey
Journal: JAMA (1966)

<h3>To the Editor:—</h3> The treatment of James Ewing in the July 18th issue was well done. An added point should be of interest. Like Delafield, Ewing was previously memorialized by the naming of the New York City Cancer unit in our Memorial-Sloan Kettering Cancer Center as the James Ewing Hospital. It stands on First Avenue between 67th and 68th streets.
Coronary Artery Pressure in the Perfused Heart
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
EFFECTIVENESS OF INFANT WELFARE CLINICS FROM A MEDICAL POINT OF VIEW
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Pulmonary and Gastrointestinal Exposure to Cadmium Oxide Dust in a Battery Factory
Authors: E. Adamsson, M. Piscator, K. Nogawa
Journal: Environmental Health Perspectives (1979)

The elimination of cadmium in feces was studied in a group of 15 male workers exposed to cadmium oxide dust in a nickel-cadmium battery factory. The elimination of cadmium in feces was on the average 619 and 268 microgram/day in seven smokers and eight nonsmokers, respectively. The corresponding ranges were 97-2577 and 31-1102 microgram/day. The cadmium concentrations in blood were significantly higher in smokers than in nonsmokers, both before and after one month of vacation. Among the smokers there was a significant decrease in the cadmium concentrations during the vacation period, but not among the nonsmokers. It was estimated that cadmium naturally occurring in food and cigarettes, cadmium excreted from the gastrointestinal tract, and cadmium transported from the lungs by mucocillary clearance to the gastrointestinal tract only could explain up to 100 microgram of the cadmium in the feces. Since even among some nonsmokers much higher values for fecal cadmium were recorded, this was interpreted as being the result of ingestion of cadmium from contaminated hands and other body surfaces. Among the smokers, direct oral contact with contaminated cigarettes or pipes is an additional factor; the smokers also inhale cadmium in the tobacco smoke from contaminated cigarettes. Part of that cadmium is transferred to the gastrointestinal tract by mucociliary clearance and also adds to the fecal cadmium.
A Dream
Authors: Hope K. Haefner
Journal: JAMA (1991)

11:55PM Shhh. Little Diane dreams. Her red hair curls softly across the pillow and strays over her calm, pale face. She is running. Where are you going, Diane? She advances awkwardly, as her legs, too long for her body, become entangled, tripping her as she reaches for the aluminum door. Slender fingers wrap themselves around the smooth handle. They whiten, trapping the blood at the tips, as she strains to open the door. One small branch of light breaks through, widening as she opens it farther. She squints at the brightness of the room. What do you see, Diane? Her face tenses. Large men, their backs to the child, seem barely to speak. Their bodies, uniformly clad in hospital green, bend over a sterile table. They leave silently, some together, others alone. They do not notice Diane trembling in the corner. With an expression of terror, she approaches the table.
468P Osimertinib in patients with T790M mutation positive advanced non-small cell lung cancer (NSCLC): Korean subgroup analysis from pooled phase II data
Authors: M-J. Ahn, J-S. Lee, J-Y. Han, D-W. Kim, B.C. Cho, J.H. Kang, S-W. Kim
Journal: Annals of Oncology (2016)
Letter: Women doctors in the N.H.S.
Authors: W Jedrzejczak, M Siekierzyn'ski
Journal: BMJ (1975)

cancer were fewer thn those of Professor Cooper and his colleagues but we included only selected cases.Patients with bacterial infection, confinned by the nitroblue tetra- zolium test,8 were excluded.That raised serum muramidase levels may in some cases of untreated cancer be due to local bacterial infection cannot be ruled out, partioularly in colorectal canoer, which often infiltrates the superficial layer of the mucous membrane.This may explain why only some patients bave raised serum muranidase levels.The observation that bacterial infection is associated with raised serum muramidase levels prompted us to measure these in 40 patients, of whom 28 had a local and 12 a systemic infection.Some of the patients had cancer and others did not.The serum muraxnidase level was raised in all of the patients with systemic infections but in only five of the 28 with local infections.All of these five had cancer and their local infec- tion was in tissue surrounding the neoplasm.The nitroblue tetrazolium test was positive in four out of the five.Our findings lead us to believe that a raised serum muramidase level in some cancer patients is only a secondary phenomenon and is of no diagnostic or prognostic value.-Weare, etc.,
The pains of love: hemoperitoneum following sexual intercourse
Authors: B. E. Ferrara
Journal: JAMA (1986)

<h3>To the Editor.—</h3> We write with reference to the recent article by Swedberg et al<sup>1</sup>entitled "Comparison of Single-Dose vs One-Week Course of Metronidazole for Symptomatic Bacterial Vaginosis." We find it difficult to support the authors' conclusions that prolonged therapy with metronidazole is more effective than "one-dose" therapy since such a large number of subjects were unavailable for follow-up. Only 65% (64/98) completed the trial, with most of the dropouts coming from the single-dose group. It is quite likely that those unavailable for follow-up had become asymptomatic and were therefore more likely to be cured. This could well reduce or abolish the differences in outcomes between the two study groups. The exclusion of any demographic data makes it difficult to determine the applicability of the results to other practices. In addition, the small number of patients makes it impossible to draw any conclusions about the efficacy of treating sexual
The Demonstration of Syphilitic Infection by Vaccination with Lymph from a Syphilitic Child. Inefficiency of Excision.
Journal: JAMA (1884)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Retinoic Acid Induced Differentiation and Commitment in HL-60 Cells
Authors: Peter A. Meyer, Clemens Kleinschnitz
Journal: Environmental Health Perspectives (1990)

Human leukemic HL-60 cells are an established model for studies of differentiation induction. Retinoic acid (RA), 2 x 10(-6) M, was used to induce terminal differentiation, assayed as nitroblue tetrazol reduction (NBT) and expression of monocytic surface antigens, which were detected by monoclonal antibody Leu M3. In addition, transferrin receptor expression and the number of S + G2 + M-phase cells were determined. With a 12-hr RA incubation, only a decrease of transferrin receptor expression was found, with no change in other parameters. At least 96 hr RA incubation was necessary to induce terminal differentiation, with most cells being positive for NBT and M3. Cells induced with RA for 12 hr and subsequently recultured in liquid culture gradually expressed the differentiated phenotype and lost transferrin receptor expression. The number of S + G2 + M-phase cells in the cultures decreased drastically. After 12 hr RA exposure and 120 hr reculture without RA, the differentiation profile was comparable to that of cells that had been induced with RA for 96 hr. In reculture for up to 120 hr there was no evidence of loss of viability or regrowth of possibly residual undifferentiated cells. From these studies, we conclude that HL-60 cells become committed to terminal differentiation after half a generation-time exposure to RA and remain committed for at least six generation times.
Skin cover.
Authors: D M Davies
Journal: BMJ (1985)

The authors have investigated whether treatment of sleep apnoea with nasal continuous positive airway pressure (nCPAP) improves depressive symptoms, personal activities of daily living (ADL), cognitive functioning and delirium in patients that have suffered a stroke. Sixty-three patients consecutively admitted to a stroke rehabilitation unit 2–4 weeks after a stroke, with an apnoea/hypopnoea index ≥15, were randomized to either nCPAP treatment (n=33) or a control group (n=30). Four patients dropped out after randomization. Both groups were assessed at baseline and after 7 and 28 nights using the Montgomery-Åsberg Depression Rating Scale (MADRS), Barthel-ADL index, and the Mini-Mental State Examination (MMSE) scale. Compared to the control group, depressive symptoms (MADRS total score) improved in patients randomized to nCPAP treatment (p=0.004). No significant treatment effect was found with regard to delirium, MMSE or Barthel-ADL index. Delirium and low cognitive level (MMSE score) explained poor compliance with nCPAP. Depressive symptoms are reduced through nasal continuous positive airway pressure treatment in patients with severe stroke and sleep apnoea. Compliance with nasal continuous positive airway pressure treatment is a problem in stroke patients, especially when delirium and severe cognitive impairment occur.
Treating the patient with sore throat. Theory v practice
Authors: A. L. Bisno
Journal: JAMA (1983)

There is no doubt that the incidence of acute rheumatic fever (ARF) in North America and western Europe has plummeted over the course of the 20th century. The reasons for this decline are poorly understood but probably relate to a combination of factors, including improved socioeconomic conditions, widespread use of antibiotics in therapy for acute respiratory tract infections, and changes in the rheumatogenic potential of currently prevalent group A streptococcal strains.<sup>1</sup>The decline in ARF does<i>not</i>, however, seem to be due to a disappearance of group A streptococci from the environment. The organism is readily isolated from the throats of a substantial minority of children initially seen with acute pharyngitis. Whatever the reasons, the incidence of ARF in certain parts of the United States has dropped as low as one case per 200,000 school-aged children per year.<sup>2</sup> Currently accepted strategies for management of simple sore throat are
Expression of concern: Which specific modes of exercise training are most effective for treating low back pain? Network meta-analysis
Journal: British Journal of Sports Medicine (2020)

As discussed in a recent editorial, the British Journal of Sports Medicine (BJSM) rescinds the Expression of Concern [1] for a recent network meta-analysis (NMA) [2] that was issued solely on the basis of comments by Professor Maher and colleagues [3]. The original authors (Dr Belavy and colleagues) have responded [4]. The original NMA paper did not require any changes. We editors of the BJSM have full confidence in the findings of the NMA [2]. The findings of the NMA inform clinical practice and can serve to inform clinical practice guidelines.Karim Khan, MD, PhDEditor-in-Chief, BJSMJuly 27th, 2020
Disparities in Premature Deaths From Heart Disease—50 States and the District of Columbia, 2001
Journal: JAMA (2004)

In 2001, heart disease accounted for approximately 29.0% of deaths among U.S. residents; 16.8% of those deaths occurred among persons aged <65 years. Although mortality rates from heart disease have decreased, the decline has not been uniform for all populations. One of the two overall national health objectives for 2010 is to eliminate health disparities among different segments of the U.S. population. To better understand these disparities, CDC analyzed death certificate data for premature deaths from heart disease occurring in 2001. This report summarizes the results of that analysis, which indicated that the proportion of premature heart disease deaths varied by state and was higher among blacks, American Indians/Alaska Natives (AI/ANs), Asians/Pacific Islanders (A/PIs), and Hispanics. Reducing premature death from heart disease and eliminating disparities will require preventing, detecting, treating, and controlling risk factors for heart disease in young and middle-aged adults.