tbuckley/cabot-search huggingface dataset:
Sanatoria for Consumptives. A Critical and Detailed Description, Together with an Exposition of the Open-Air Hygienic Treatment of Phthisis.
Journal: JAMA (1902)

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Medical News
Journal: JAMA (1972)

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Cosmetic outcome after intraoperative radiotherapy or external beam radiotherapy for early breast cancer: An objective assessment of patients from a randomized controlled trial.
Authors: Mohammed R. Keshtgar, Norman R. Williams, Tammy Corica, Max Bulsara, Christobel Saunders, Henrik Flyger, Niels Bentzon, Jaime S. Cardoso, Nikolaus Michalopoulos, David John Joseph
Journal: Journal of Clinical Oncology (2013)

59 Background: The international randomised contolled TARGeted Intraoperative radioTherapy (TARGIT) trial has demonstrated non-inferiority between the novel technique of TARGIT (intra-operative radiotherapy with Intrabeam) and conventional whole-breast external beam radiotherapy (EBRT) in women with early breast cancer, in terms of the primary outcome measure of risk of local relapse within the treated breast. With very low recurrence rates, cosmesis becomes an increasingly important outcome of breast conserving treatment with both surgery and radiotherapy. This study was performed to determine if the single high dose of TARGIT leads to impaired cosmesis. Methods: A validated, objective assessment tool for evaluation of cosmetic outcome was used. Frontal digital photographs were taken at baseline (before TARGIT or EBRT) and yearly thereafter for up to five years. The photographs were analysed by BCCT.core software which produces a composite score based on symmetry, colour and scar. Results: 342 patients were assessed, all over 50 years old with a median age at baseline of 64 years (IQR 59 to 68). The scores were dichotomised into Excellent and Good (EG), and Fair and Poor (FP). There were statistically significant increases in the odds of having an outcome of EG for patients in the TARGIT group relative to the EBRT group at year 1 (OR = 2.07, 95% CI 1.12 to 3.85, p = 0.021) and year 2 (OR = 2.11, 95% CI 1.0 to 4.45, p = 0.05). Conclusions: Following an objective assessment of aesthetic outcome in patients from a randomised setting, this study demonstrates that those treated with targeted intraoperative radiotherapy have a superior cosmetic result compared with those patients who received conventional whole-breast external beam radiotherapy.
Classifying Pediatric HIV Infection
Journal: JAMA (1994)

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Obituary Listing
Journal: JAMA (1987)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
"Budesonide/formoterol maintenance and reliever therapy: an effective asthma treatment option?" C. Vogelmeier, A. D'Urzo, R. Pauwels , J.M. Merino, M. Jaspal, S. Boutet, I. Naya and D. Price. Eur Respir J 2005; 26: 819-828.
Journal: European Respiratory Journal (2011)
Therapeutics.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
敏感皮肤患者中定量感觉检测
Authors: F. Huet, A. Dion, A. Batardière, A.S. Nedelec, F. Le Caër, P. Bourgeois, E. Brenaut, L. Misery
Journal: British Journal of Dermatology (2018)

敏感皮肤定义为, 作为正常不会导致如瘙痒、疼痛或烧灼感等症状的刺激的反应, 所发生的令人不快的前述感觉。它不包括可以导致上述症状的皮肤病 (如湿疹) 患者。据报告, 敏感皮肤影响欧洲 50% 女性和 30% 男性, 并降低他们的生活质量。其可通过问卷 Sensitive Scale 进行测量。尚不清楚这些症状是因皮肤血供变化 (一种皮肤屏障缺陷) 还是因为供应表皮 (皮肤的最外层) 的神经变化导致。来自法国 Brittany 的作者们在 21 名敏感皮肤综合征(Sensitive Scale 评分超过 50)个体和 21 名对照受试者 (Sensitive Scale 评分低于 20) 中定量了热‐痛阈值 (一个触觉敏感性指标)。作者们还使用两份问卷定量分析两组的神经性 (神经‐相关) 疼痛的程度。他们发现, 与对照相比, 敏感皮肤个体的热‐痛阈值显著下降和神经性疼痛显著增高。他们得出结论称, 这些发现支持敏感皮肤与皮肤神经末梢功能异常有关的观点。传统上通过保湿剂治疗敏感皮肤, 但作者们指出, 至少受影响更严重的个体需要不同的治疗方法。 Linked Article:Huet et al. Br J Dermatol 2018; 179:1157–1162
THE NAVAL RE-ORGANIZATION BILL.
Journal: JAMA (1895)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Edmund Lesser's Lehrbuch der Haut- und Geschlechtskrankheiten.
Journal: JAMA (1928)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Benchmarking the US Physician Workforce
Authors: David C. Goodman
Journal: JAMA (1996)

<h3>Objective.</h3> —To propose population-based benchmarking as an alternative to needs- or demand-based planning for estimating a reasonably sized, clinically active physician workforce for the United States and its regional health care markets. <h3>Design.</h3> —Cross-sectional analysis of 1993 American Medical Association and American Osteopathic Association physician masterfiles. <h3>Population.</h3> —The resident population of the 306 hospital referral regions in the United States. <h3>Main Outcome Measures.</h3> —Per capita number of clinically active physicians by specialty adjusted for age and sex population differences and out-of-region health care utilization. The measured physician workforce was compared with 4 benchmarks: the staffing within a large (2.4 million members) health maintenance organization (HMO), a hospital referral region dominated by managed care (Minneapolis, Minn), a hospital referral region dominated by fee-for-service (Wichita, Kan), and the proposed "balanced" physician supply (50% generalists). <h3>Results.</h3> —The proportion of the US population residing in hospital referral regions with a higher per capita generalist workforce than the benchmark was 96% for the HMO benchmark, 60% for Wichita, and 27% for Minneapolis. The specialist workforce exceeded all 3 benchmarks for 74% of the population. The per capita workforce of generalists was not related to the proportion of generalists among regions (Pearson correlation coefficient=0.06;<i>P</i>=.26). <h3>Conclusions.</h3> —Population-based benchmarking offers practical advantages to needs- or demand-based planning for estimating a reasonably sized per capita workforce of clinically active physicians. The physician workforce within the benchmarks of an HMO and health care markets indicates the varying opportunities for regional physician employment and services. The ratio of generalists to specialists does not measure the adequacy of the supply of the generalist workforce either nationally or for specific regions. Research measuring the relationship between physician workforces of different sizes and population outcomes will guide the selection of future regional benchmarks.
Pneumocystis carinii pneumonia among patients without AIDS at a cancer hospital
Authors: K. A. Sepkowitz
Journal: JAMA (1992)

<h3>Objectives.</h3> —To determine the predisposing factors, attack rate by underlying disease, and outcome of<i>Pneumocystis carinii</i>pneumonia among patients without the acquired immunodeficiency syndrome (AIDS) at a cancer center. <h3>Data Source.</h3> —Twelve-year retrospective review from a tertiary-care cancer center. <h3>Study Selection.</h3> —One hundred forty patients, constituting 142 cases, with morphologically proved<i>P carinii</i>pneumonia. <h3>Data Synthesis.</h3> —Hematologic malignancy (47%) (including lymphoma [27%] and leukemia [18%]), solid tumor (31 %), or bone marrow transplantation (18%) was the underlying condition in the majority of cases. Twenty-five cases (18%) were diagnosed at autopsy. All but seven patients had previously established predisposing factors for<i>P carinii</i>pneumonia, including corticosteroid use in 87%. The attack rate for hospitalized patients with primary or metastatic brain tumor increased during the 12-year interval. The attack rates for hospitalized patients with hematologic neoplasm or bone marrow transplantation were stable. The overall mortality rate did not change during the period reviewed. <h3>Conclusions.</h3> —Despite the availability of effective prophylaxis,<i>P carinii</i>pneumonia continues to occur among patients with neoplastic disease. In addition to patients with certain hematologic neoplasms, those with primary or metastatic brain neoplasm who receive corticosteroids are at risk for the development of<i>P carinii</i>pneumonia and should receive<i>P carinii</i>pneumonia prophylaxis. (<i>JAMA</i>. 1992;267:832-837)
Heparanase Promotes the Spontaneous Metastasis of Myeloma Cells to Bone.
Authors: Yang Yang, Veronica MacLeod, Manali Bendre, Yan Huang, Allison M. Theus, Hua-Quan Miao, Paul Kussie, Shmuel Yaccoby, Joshua Epstein, Larry J. Suva, Thomas Kelly, Ralph D. Sanderson
Journal: Blood (2004)
Commentaire du travail de Erichsen R et al., pp. 517
Authors: Gilles Lesur, Maxime Palazzo, Nicolas Musquer, Marine Camus, Julien Branche
Journal: Endoscopy (2015)

See also: Long-term mortality and recurrence after colorectal cancer surgery with preoperative stenting: a Danish nationwide cohort studyEndoscopy 2015; 47(06): 517-524DOI: 10.1055/s-0034-1391333
Maladies de l'intestin. Série II: Diverticules, mégacolon, dysenterie, colites infantiles, diagnostic de l'appendicite chronique, tuberculose, cancer, traitement bismuthé dans les affections gastrointestinales.
Journal: JAMA (1933)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Editors' Reply
Authors: Virginia Barbour, Barbara Cohen, Gavin Yamey
Journal: PLoS Medicine (2005)

I previously criticised the effective "statute of limitations" in several leading general medical journals "whereby authors of papers are immune to disclosure of methodological weaknesses once some arbitrary (short) period has elapsed" [2].Such a time limit discourages post-publication peer review, with potential correspondents deterred by the short and unambiguous deadline.I suggested that journals with such a policy should reconsider.The word limit on that article precluded additional adverse comments on journals' word limits for letters, although they were presented in Table 2 of that article [2].Subsequently, three of the six journals did revise their instructions [3-5], but each imposed tougher restrictions on letters, reducing either the maximum time limit, the maximum length, or both.The strictest current requirements are a two-week limit by The Lancet and a 175-word limit by the New England Journal of Medicine.Editors are seemingly falling over themselves to speed up and shorten letters, but this behaviour is inappropriate for a scientifi c journal.The key characteristic of science is not its infallibility, a quality it clearly does not and cannot have, but its self-correcting ability.The decision by medical editors to stifl e debate is misguided [2,6].A time limit, especially a very short one, signals that speed is more important than content, that convenience takes precedence over science.While it is reasonable to encourage early comments, there should be no time limit on comments aimed at clarifying or criticising study methodology.Likewise, it will often be impossible to explain the subtleties of methodological problems in 400 words, and impossible in only 175.Additional restrictions on the number of authors and references are also questionable.I am disappointed that PLoS Medicine has imposed a time limit of four weeks on correspondence.As explained above, I believe that such a limit is mistaken.
Rethinking Breast Cancer Risk and the Environment: The Case for the Precautionary Principle
Authors: Devra Lee Davis, Deborah Axelrod, Lisa Bailey, Mitchell Gaynor, Annie J. Sasco
Journal: Environmental Health Perspectives (1998)

The World Health Organization recently reported that breast cancer has become the most common cancer in women throughout the world. Known risk factors account for less than half of all cases of breast cancer, and inherited germ line mutations occur in at most only 10% of all cases. Cumulative exposure to estradiol and other hormones links many of the established risk factors for breast cancer. This paper reviews epidemiologic and toxicologic evidence on breast cancer risks and presents a comprehensive construct of risk factors intended to focus on the identification of those factors that can be controlled or modified. We attempt to provide a framework for interpreting the etiologic interplay of endogenous metabolic changes and environmental changes in the etiology of breast cancer. The construct we develop distinguishes between those risk factors that are directly causal, such as ionizing radiation and inherited germ cell defects, those vulnerability factors that extend the time period during which the breast undergoes development, and those contributing factors that increase total hormonal stimulation of the breast. Some hormonally active compounds, such as those in soy and broccoli and other phytoestrogen-containing foods, can be protective against breast cancer, while others, such as some environmental contaminants, appear to increase the risk of the disease by increasing levels of harmful hormones. Efforts to explain patterns of breast cancer should distinguish between these different risk factors. Identification of vulnerability and contributing risk factors can foster the development of public policy to reduce the burden of this prevalent cancer. Prudent precautionary principles suggest that reducing exposure to avoidable or modifiable risk factors should receive high priority from the public and private sectors.
Metabolic Alkalosis And Cirrhosis
Journal: JAMA (1966)

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