tbuckley/cabot-search huggingface dataset:
Abstract P020: <sup>1</sup> H Nmr Metabonomic Profiling Identifies Novel Biomarkers for Cardiovascular Mortality
Authors: Abtehale Al-Hussaini, Tsung Tan, Joban Sehmi, Paul Elliott, Mika Ala-Korpela, Jaspal S Kooner, John C Chambers
Journal: Circulation (2012)

Background Cardiovascular disease (CVD) is the leading cause of death world-wide. Existing tools for identification of CVD risk have modest predictive power and discrimination. New biomarkers for CVD prediction are urgently needed. Hypothesis We have used 1 H NMR metabonomic profiling of serum to identify novel biomarkers for incident CVD. Methods We investigated 9,179 men and women participating in the London Life Sciences Population study. Participants were recruited between 2002-2008 from the lists of 58 GPs in London UK, and assessed for baseline CVD risk factors, including smoking, body mass index, waist circumference, blood pressure, fasting glucose and lipid profile. Participants were followed for CVD mortality to July 2011 (mean 5.5 years per person). 1 H NMR metabonomic profiling was done on baseline serum sample by 12T Bruker spectrometer, with quantification of 44 fatty acid and low molecular weight markers. Results There were 161 CVD deaths. Compared to survivors, people with CVD death were older, had higher prevalence of type-2 diabetes and cigarette smoking, higher blood pressure, body mass index, glucose, and lower total and HDL cholesterol (Table). Framingham risk scores were higher in cases with CVD death than survivors (18.7±0.9% vs. 11.4±0.7%, P=10 -31 ). We found six NMR metabolites associated with incident CVD at P&lt;0.05; odds ratios (95%CI) for CVD per 1SD increase in biomarker ranged from 1.19 (1.07-1.33, P=0.007) to 1.65 (1.44-1.89, P=3x10 -13 ). The associations of NMR metabolites with CVD were not materially changed by adjustment for age, gender and Framingham risk score. The AUC for prediction of incident CVD was 0.74 using Framingham risk score alone, and 0.77 with incorporation of metabonomic measures. Conclusions We identified six novel biomarkers for incident CVD; these are independent of known CVD risk factors and may improve CVD risk prediction. Our findings demonstrate the potential utility of metabonomic profiling for biomarker discovery and risk stratification. CVD deaths Survivors P Total no of people 161 9018 Age (years) 61.6 (0.5) 53.4 (0.4) 0.001 Male gender (%) 98.2 85.8 &lt;0.001 Smoking (%) 73 49 &lt;0.001 Diabetes (%) 49 20 &lt;0.001 Systolic blood Pressure (mmHg) 144.7 (22.7) 134.0 (19.2) &lt;0.001 Body mass index (kg/m 2 ) 28.4 (5.6) 27.3 (4.3) 0.002 Total cholesterol (mmol/L) 4.8 (1.2) 5.2 (1.1) &lt;0.001 HDL cholesterol (mmol/L) 1.20 1.25 0.064 Glucose (mmol/L) 7.1 5.9 &lt;0.001 Results provided as mean or %.
Metabolism, New York
Journal: JAMA (1970)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Neoplastic epidural spinal cord compression. A current perspective
Authors: H. Gilbert
Journal: JAMA (1978)

TREATMENT of epidural involvement by metastatic cancer should be directed to the totality of the invariably present widespread metastatic systemic disease accompanying it. In contrast to patients with metastatic brain disease who frequently have interference with cognitive function, those with epidural compression usually experience the tragedy of remaining fully alert but totally paralyzed. Epidural metastases are particularly devastating in that a growing mass in a closed compartment with a marginal vascular supply can give rise to sudden paraplegia and permanent loss of function; over-whelming nursing problems and untold financial burden result. Patients with back pain from metastatic neoplasm are usually treated for "bone metastasis," and little consideration is paid to the nuances of the specific symptom complex. "Soft" neurological signs, such as pain or sensory changes in a dermatome (radicular) distribution, or minimal weakness may indicate cord compression. All of our efforts should be directed at detecting compression at this
奥马珠单抗治疗自发慢性荨麻疹的成本效益
Authors: T.A. Kanters, H.B. Thio, L. Hakkaart
Journal: British Journal of Dermatology (2018)

自发慢性荨麻疹(CSU)是一种皮肤病,会引起持续至少6周的瘙痒荨麻疹,且没有明显的外部触发因素。CSU会影响患者的生活质量以及学业和工作表现。CSU还会因为医疗成本、休假时间等因素对社会和经济造成影响。根据国际建议,CSU应先使用抗组胺药治疗,其剂量可以增加(加量)。某些患者还会接受白三烯拮抗剂(LTRA)治疗。如果上述治疗无效,医生可以开具奥马珠单抗或环孢素之类的药物。环孢素已被证明有效,但是有潜在副作用。奥马珠单抗是辅助治疗;患者要同时接受抗组胺药和LTRA治疗。奥马珠单抗是CSU的有效疗法,可减轻症状。但是,奥马珠单抗相比现有疗法价格更贵。为对抗不断上升的医疗成本,医疗保健机构在推荐采用何种治疗时越来越多地考虑成本效益因素。在本项研究中,研究人员构建了一种衡量成本效益的方法(模型)来评估奥马珠单抗的成本效益。本项研究由荷兰的研究人员开展,旨在确定奥马珠单抗与标准护理(即加量的抗组胺药)相比的成本效益。该研究调查了生活质量、医疗保健方面的成本、患者和家庭费用(非正式护理费用)以及其他方面的成本。奥马珠单抗每4周治疗的药物成本是745欧元,而标准护理的药物成本只有32欧元。此外,奥马珠单抗每次注射还需要14欧元的给药费用。然而,其他方面的成本(即生产力成本,比如能够工作)在两种疗法中都占据最大份额,但在奥马珠单抗治疗的成本中份额最低。这些间接成本的节省很大程度上弥补了增加的药物成本。本项研究表明,奥马珠单抗比标准护理更具效益,但也更为昂贵。不过,它仍被视为具有成本效益。
Hypersensitivity alveolitis
Authors: V. A. Marinkovich
Journal: JAMA (1975)

Hypersensitivity alveolitis developed in an 11-year-old girl during heavy exposure to mold spores contaminating the straw filters of an evaporation-type home air cooler. It is likely that the causative organism was<i>Micropolyspora faeni</i>, the mold responsible for farmer's lung. (<i>JAMA</i>231:944-947, 1975)
BOOK REVIEW
Authors: S. GORE
Journal: JNCI Journal of the National Cancer Institute (1995)

Journal Article BOOK REVIEW Get access Bone Marrow Disorders: the Biological Basis of Treatment, 2nd ed . A. J. Barrett M. Y. Gordon . Oxford, England : Blackwell Scientific Publications , 1993 , 416 pp., illus. $135.00, ISBN 0-632-03353-3 . STEVEN GORE, M.D. STEVEN GORE, M.D. The Johns Hopkins Hospital Oncology 2-109 600 N. Wolfe St.Baltimore, MD 21287 Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 87, Issue 1, 4 January 1995, Pages 54–55, https://doi.org/10.1093/jnci/87.1.54 Published: 04 January 1995
SCHOOL HOURS.
Journal: JAMA (1892)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Respiratory Distress from Congenital Lingual Cysts
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
2011 ACCF/AHA Focused Update Incorporated Into the ACC/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction
Authors: Jeffrey L. Anderson, Cynthia D. Adams, Elliott M. Antman, Charles R. Bridges, Robert M. Califf, Donald E. Casey, William E. Chavey, Francis M. Fesmire, Judith S. Hochman, Thomas N. Levin, A. Michael Lincoff, Eric D. Peterson, Pierre Theroux, Nanette Kass Wenger, R. Scott Wright
Journal: Circulation (2011)
CDC Discontinues Distribution of Primaquine
Journal: JAMA (1991)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Gangrene of the Leg during Warfarin Treatment in a Patient with Cancer
Journal: Annals of Internal Medicine (2001)

Summaries for Patients16 October 2001Gangrene of the Leg during Warfarin Treatment in a Patient with CancerSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-135-8_Part_1-200110160-00005 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail What is the problem and what is known about it so far?Patients with cancer sometimes develop blood clots in the deep veins of the leg, a condition known as deep venous thrombosis. In rare cases, blood clots in the deep veins of the leg become so extensive, involving both large and small blood vessels, that they reduce blood and oxygen supply to tissues. This can cause gangrene (rotting of the tissues). The drug warfarin is typically used to treat deep venous thrombosis. Warfarin thins the blood by interfering with normal blood clotting. It helps the body's normal systems for ... Author, Article, and Disclosure InformationAffiliations: The summary below is from the full report titled “Venous Limb Gangrene during Warfarin Treatment of Cancer-Associated Deep Venous Thrombosis.” It is in the 16 October 2001 issue of Annals of Internal Medicine (volume 135, pages 589-593). The author is TE Warkentin.Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. The summaries may be reproduced for not-for-profit educational purposes only. Any other uses must be approved by the American College of Physicians-American Society of Internal Medicine. Previousarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoVenous Limb Gangrene during Warfarin Treatment of Cancer-Associated Deep Venous Thrombosis Theodore E. Warkentin Venous Limb Gangrene during Warfarin Treatment of Cancer-Associated Deep Venous Thrombosis Theodore E. Warkentin Metrics Cited byState Wiretaps and Electronic Surveillance After September 11 16 October 2001Volume 135, Issue 8_Part_1Page: I-49KeywordsBlood coagulationBlood vesselsCancer treatmentDeep vein thrombosisHematologic testsOxygenPatientsProteinsThrombosisVeins ePublished: 16 October 2001 Issue Published: 16 October 2001 Copyright & PermissionsCopyright © 2001 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
PECULIAR STATUS OF NEBRASKA MEDICAL LAW.
Journal: JAMA (1900)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
DISSEMINATED ROSACEA
Authors: R. MARKS, E. WILSON JONES
Journal: British Journal of Dermatology (1969)

SUMMARY.— Fourteen patients are described who, in the course of typical facial rosacea, developed papular lesions on the limbs similar in appearance to those on the face. In some cases the lesions were small and numerous; in others the individual lesions Mere large (up to 1 cm. in diameter) dark red or mauve and deeply set. The histology of these extra‐facial lesions resembles that of the facial lesions as far as the inflammatory cellular infiltrate is concerned but there is a more prominent vascular component. The relationship of these lesions to rosacea is discussed.
Nature of Retinal Emboli in Internal Carotid Sclerosis
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
New approaches to CPR. Four hands, a plunger, or a vest
Authors: H. R. Halperin
Journal: JAMA (1992)

A major stimulus to improve methods of cardiopulmonary resuscitation (CPR) has come from the realization that blood flow during conventional CPR is marginal, particularly the flow to the heart. To restart the heart, if initial defibrillation fails (or is not possible), coronary flow must be provided.<sup>1</sup>With well-performed CPR together with optimal use of epinephrine, brain blood flow probably reaches 30% to 60% of normal; however, myocardial blood flow is much more limited, in the range of 5% to 20% of normal. Repeated studies in animals and important confirmatory studies in man have shown a strong correlation between restarting the heart and higher levels of coronary blood flow.<sup>1-3</sup>In animals, coronary flow correlates strongly with the pressure gradient between the aorta and the right atrium. In man, restarting the heart has been shown to correlate with this pressure gradient. A pressure gradient between the aorta and right atrium,
The AMA, Tobacco, and the Public Health
Authors: Linda Emanuel
Journal: JAMA (1996)

<h3>To the Editor.</h3> —Your devotion of an entire issue of<i>JAMA</i>to the murderous secret of Brown and Williamson is appropriate.<sup>1</sup>Top-quality research confirming the addictive nature of nicotine and the carcinogenic nature of tobacco was suppressed for the sake of the industry's financial interest. Counteraction is due. Along with the actions you list to counter the tobacco industry influence, the medical world should publicly appeal to pharmacists and pharmacies to eschew sale of tobacco on their premises. It is astonishing that the source of curative products should be simultaneously selling addictive poisons. The tobacco industry must revel in the implicit endorsement brought by the juxtaposition of medicines with their packets of cigarettes. But there is another lesson in the Brown and Williamson exposure. In recent months, there have been wholesale attacks on government-funded medical research programs. The justification is generally that public money should not go to science;
Abstracts
Journal: Annals of the Rheumatic Diseases (1962)

de Bouillaud.)LUTEM- BACHER, R. (1961).Arch.Mal C&rur, 54, 1177. 2 figs.This paper sets out, with numerous references to the literature, the general thoughts of the author on various manifestations of rheumatic fever.In children, he states, myocarditis plays the main role, whereas valvulitis is exceptional and does not lead to permanent lesions, the murmurs which are heard being a sign of myocarditis.The presence of Aschoff bodies and fibrinoid necrosis are the hallmarks of the underlying inflammatory process.In the adult, although the clinical manifestations are different, the same histological signs are found.Late recrudescences of rheumatic fever do not affect the condition of a diseased sclerosed valve, although murmurs may be modified by myocarditis or spread of the disease to another valve.The differences in behaviour of the rheumatic process in the child and in the adult are explained on the basis of supposed differences in the permeability of the ground substance.
Classic Pages
Journal: Circulation Research (1970)

the spleen, thi* organ was isolated and perfused with blood from a donor cat that w*.free of radioactive material.Cats were given 200 |ie./kgm.OL.'Hnoradrenaline (10 mc./mgm.) in the forelunb vein.Three hours later the animal* were anMthetim) with pentobarbitone and givan 3000 U.S.P. unit* of heparin.
INTESTINAL AND HEPATIC REACTIONS IN ANAPHYLAXIS
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
ACUTE RHINITIS.
Journal: JAMA (1993)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Serum ferritin and bone marrow iron in patients undergoing continuous ambulatory peritoneal dialysis
Authors: A. B. Blumberg
Journal: JAMA (1983)

In 20 patients undergoing continuous ambulatory peritoneal dialysis (CAPD), serum ferritin concentration (radioimmunoassay) was compared with bone marrow iron stores (graded semiquantitatively). A close correlation between the two parameters was found. Patients with decreased iron stores (8/20) had serum ferritin concentrations below 70 ng/mL; those with normal or increased iron stores had concentrations above 96 ng/mL. It is concluded that serum ferritin concentrations adequately reflect bone marrow iron stores and are useful as a guide to iron-replacement therapy in patients undergoing CAPD. (<i>JAMA</i>1983;250:3317-3319)