tbuckley/cabot-search huggingface dataset:
Salivary Electrolytes In Digitalis Toxicity
Journal: JAMA (1973)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
HIV/AIDS Diagnoses Among Blacks—Florida, 1999-2004
Journal: JAMA (2007)

In 2004, Florida accounted for 11% of the total number of acquired immunodeficiency syndrome (AIDS) cases in the United States, ranking third behind New York and California. Florida also had the second-highest reported AIDS diagnosis rate (behind New York). During 2004, non-Hispanic blacks accounted for 14% of the Florida population but 52% of the 77,421 persons in Florida living with human immunodeficiency virus (HIV)/AIDS. This report describes trends in diagnoses of HIV/AIDS cases that occurred among blacks during 1999-2004 and were reported to the Florida Department of Health. These data indicate that, during 1999-2004, the annual rate of HIV/AIDS diagnosis among blacks decreased more than the rates among other racial/ethnic groups. To examine possible explanations for this decline, HIV/AIDS diagnosis rate trends were compared with trends in gonorrhea diagnosis and publicly funded HIV testing in Florida. The results indicated that gonorrhea diagnosis rates also decreased among blacks in Florida during 1999-2004, whereas the number of HIV tests increased. These findings suggest that HIV/AIDS diagnoses in blacks might be associated with a reduction in high-risk sexual behavior and that the decline was not the result of less testing.
Adrenomyeloneuropathy in Patients with ‘Addison's Disease’: Genetic Case Analysis
Authors: Sagarika Mukherjee, Elizabeth Newby, John N Harvey
Journal: Journal of the Royal Society of Medicine (2006)

Objective To review the clinical presentations and diagnostic issues in adrenomyeloneuropathy and adrenoleukodystrophy, which are different presentations of the same single gene disorder. Design Observational study. Participants Three generations of an affected kindred. Intervention None. Main outcome measures Neurological features suggestive of adrenoleukodystrophy or adrenomyeloneuropathy. Measurement of very long chain fatty acids. Molecular analysis of the adrenoleukodystrophy gene. Results Three adults presented with adrenomyeloneuropathy and two children with adrenoleukodystrophy. Circulating concentrations of long chain fatty acids were raised consistent with clinical features. A mutation in exon 6 of the adrenoleukodystrophy gene (P543L) was identified. This had not previously been identified but has subsequently been reported by other groups. Conclusions Adrenomyeloneuropathy should be considered in the differential diagnosis in male patients presenting with adrenal failure. Early diagnosis allows genetic counselling in such families and may become more important as treatment strategies evolve.
Necrotizing enterocolitis, formula feeding, and colostrum
Authors: H. C. Borresen
Journal: JAMA (1979)

<h3>To the Editor.—</h3> In their article "Preventing Necrotizing Enterocolitis in Neonates," Brown and Sweet (240:2452, 1978) conclude that infants at risk "must not be fed early" by mouth. They rightly advocate total intravenous feeding until oral feeding can be established. A word of caution is in order regarding the advice to postpone oral feeding. It is evident that formula feeding is what the authors have in mind. There are good reasons to believe that the conclusion will be exactly the opposite if natural breast-feeding, including early intake of raw colostrum, is meant. Fresh breast milk protects against intestinal infections.<sup>1</sup>Indeed, experimental work with rats<sup>2</sup>has shown that suckling protects newborn rats against necrotizing enterocolitis induced experimentally by hypoxia, while formula feeding allows the fulminant disease to develop. Necrotizing enterocolitis is rare in Norway. A recent report from our hospital<sup>3</sup>suggests that the common practice of early breast-feeding
Abstract P1-11-10: Sequential Versus Upfront Intensified Neoadjuvant Chemotherapy in Patients with Large Resectable or Locally Advanced Breast Cancer (INTENS), First Results from a Phase III Study of the Dutch Breast Cancer Trialists’ Group (BOOG)
Authors: BE Vriens, KK Van de Vijver, C Boetes, SM van Gastel, J Wals, TJ Smilde, LJ van Warmerdam, HW van Laarhoven, DJJ van Spronsen, GF Borm, VC. Tjan-Heijnen
Journal: Cancer Research (2010)

Abstract Background: Taxanes have an established role as (neo)-adjuvant treatment of breast cancer. In the NSABP-B30 and the BCIRG 005, adriamycin and cyclophosphamide followed by docetaxel (AC-T) was compared with docetaxel in combination with adriamycin and cyclophosphamide (TAC) in the adjuvant setting. AC-T outperformed TAC if TAC was given for 4 cycles (B-30). However, AC-T was not significantly different from TAC if TAC was given for 6 cycles (BCIRG 005). In the present study, we compared AC-T with 6 cycles of TAC in the neo-adjuvant setting. Methods: Women presenting with breast cancer, cT2≥3cm, cT3, cT4 and/or cN+, with measurable disease and no prior treatment, age ≥18 and ≥70 years and Karnofsky-Score ≥70% were eligible. Patients were randomized to AC (60/600 mg/m2 q3wk x 4 cycles) followed by T (100 mg/m2 q3wk x 4 cycles) or TAC (75/50/500 mg/m2 q3wk x 6 cycles). If indicated, trastuzumab and/or endocrine therapy were given as adjuvant treatment. The primary endpoint of this study was the pathologic complete response (pCR) rate to neoadjuvant chemotherapy at surgery. Safety data will be presented separately at a later date. Results: In total, 201 patients (n=100 AC-T, n=101 TAC) were included between February 2006 and April 2009. Baseline characteristics (ACT/TAC) were well balanced for age (median 49/49y), T-status (cT1-2 51/49%), N-status (cN0 37/40%), hormone receptor status (positive in 65/66%) and HER2 (positive in 28/18%). AC-T resulted in pCR of the breast in 28% of patients and TAC in 19% of patients (Odds ratio (OR) 1.61; 95% CI 0.79-3.33). In patients with positive lymph nodes in situ at start of chemotherapy (no sentinel node procedure), combined pCR of the breast and axilla was 19 % (n=42) and 13% (n=38). Conclusion: AC followed by T resulted in a higher pCR rate, though not statistically significant. Support: Unrestricted grants from sanofi-aventis NL BV and Amgen BV Citation Information: Cancer Res 2010;70(24 Suppl):Abstract nr P1-11-10.
Book Review A Practical Treatise on Diseases of the Skin for the Use of Students and Practitioners . By Oliver S. Ormsby, M.D., Clinical Professor and Chairman of the Department of Dermatology, Rush Medical College of the University of Chicago; with revision of the histopathology in this edition by Clark Wylie Finnerud, M.D. Fourth Edition, thoroughly revised. 1288 pp. Philadelphia: Lea and Febiger. $11.50.
Journal: New England Journal of Medicine (1934)
Journal Investigative Dermatology, Baltimore
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Gastric Acid and the Gastropancreatic Distension Reflex
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
NECROLOGY.
Authors: None E. C. H.
Journal: JAMA (1884)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Intravenously given conjugated estrogens. Lack of effect of capillary stability
Authors: L. R. Zacharski
Journal: JAMA (1973)

A double-blind crossover study comparing intravenously administered conjugated estrogens (CE) and a placebo failed to demonstrate a significant effect on capillary resistance to a standard negative pressure stress or the bleeding time in normal subjects. The occurrence of deep calf vein thrombosis within 24 hours of CE administration in a healthy 46-year-old male volunteer raised the possibility of an etiologic relationship. The study did not support the widely held contention that CE promote hemostasis in normal individuals by enhancing capillary stability.
Commentaire de travail de C. H. Houben et al., pp. 836
Journal: Endoscopy (2007)

See also: Preoperative endoscopic retrograde cholangiopancreatographic treatment of complicated choledochal cysts in children: a retrospective case seriesEndoscopy 2007; 39(09): 836-839DOI: 10.1055/s-2007-966654
RAILWAY SURGERY AT THE PAN-AMERICAN MEDICAL CONGRESS.
Journal: JAMA (1892)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Head injury-associated deaths in the United States from 1979 to 1986
Authors: D. M. Sosin
Journal: JAMA (1989)

Review of US mortality data from 1979 to 1986 identified 315 328 deaths associated with head injury, which represented 2% of all deaths, 26% of injury deaths, and an annualized head injury-associated death rate of 16.9 per 100 000 residents. Motor vehicles (57%), firearms (14%), and falls (12%) were the most frequent causes. Death rates peaked at 15 to 24 years of age and at 75 years or older, with the younger group most affected by motor vehicles (77%) and the older group by falls (43%). Although blacks and whites had similar death rates overall, age- and cause-specific rates varied considerably. The rate of head injury-associated death for males was three times that of females. Rates for head injury-associated death plateaued after declining in the early 1980s. Physicians can play an important role in primary prevention of head injury through careful prescribing of medications, patient counseling, and advocacy of proved interventions such as motor vehicle-occupant restraints. (<i>JAMA</i>. 1989;262:2251-2255)
Dose-Response Study of Chloroform Carcinogenesis in the Mouse and Rat: Status Report
Authors: Theodore A. Jorgenson, Carol J. Rushbrook, David C. L. Jones
Journal: Environmental Health Perspectives (1982)

Chloroform is being administered to male Osborne-Mendel rats and to female B6C3F1 mice at concentrations of 0 (negative control), 200, 400, 900 or 1800 ppm in the drinking water. Matched control groups of both species receive a volume of water identical to that consumed by the corresponding 1800 ppm groups. At this writing, the animals have completed 23 months on test. Negative control and CHCl3-treated rat groups have shown typical growth curves, with dose-related relative decrements in body weight evident throughout the study. Following decreases in CHCl3 groups during the first 8 weeks, rat water consumption values have continued to increase slowly, but persistent relative dose-related decrements are evident. No initial treatment-related decrements are evident. No initial treatment-related mortality was seen in the rats. Survival is 21, 41, 45, 76, 70 and 64% for the negative control, 200, 400, 900, 1800 ppm and matched control groups, respectively. Survival values for mice at three weeks were 99, 94, 74 and 76% for the 200, 400, 900 and 1800 ppm groups, respectively. Mortality was apparently related to markedly decreased fluid consumption among some of the treated mice. Subsequent mortality has been less than 15% for all mouse groups. Except for acclimation effects during the first 2-3 weeks, body weights for the treated mouse groups have been generally within 10% of negative control values. Tissue changes in decedents have been similar in treated and control groups, both in rats and mice. Terminal sacrifice and histologic evaluations will be initiated after completion of 24 months on test.
Three-Dimensional Reconstruction of Hemilarynx
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Old Men
Authors: George N. Braman
Journal: Annals of Internal Medicine (2007)

Ad Libitum15 May 2007Old MenGeorge N. Braman, MDGeorge N. Braman, MDFrom Bronx, NY 10471.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-146-10-200705150-00012 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail “That is no country for old men …”—William Butler Yeats, Sailing to Byzantium... Author, Article, and Disclosure InformationAffiliations: From Bronx, NY 10471.Current Author Address: George N. Braman, MD, 6142 Delafield Avenue, Bronx, NY 10471. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 15 May 2007Volume 146, Issue 10Page: 754KeywordsGames ePublished: 15 May 2007 Issue Published: 15 May 2007 Copyright & PermissionsCopyright © 2007 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
MELANCHOLIA.
Authors: FRANK PARSONS NORBURY
Journal: JAMA (1898)

that the particular vault was a nuisance was not presented and the case was therefore dismissed.In a prosecution for selling impure ice the party was con- victed in the police magistrate's court.From this decision and fine he appealed to the county court, where he was again convicted by a jury.In order to hasten matters and avoid long drawn-out litigation an order was then issued, after a hearing, that the complained-of ice would be destroyed if brought into the city for sale.Upon this the culprit managed to have three judges of different courts intervene with orders and injunctions preventing not only the de- struction of the ice, but further prosecutions under the ordinance which had secured his previous con- victions.These orders were based upon perjured statements of the attorney that no hearing had been given; inasmuch as the previous hearings were not of record, the falsehood could not be disproved, the unin- formed judges of appeals made a ridiculous decision to the effect that "a health commissioner had no right to issue an order to destroy property."All of which may be good law but is bad reasoning from the stand- point of a common-sense sanitarian.Judges are not well informed upon matters relating to sanitation which come before them for decision.Worse than this is the fact that from the peculiar bent of mind acquired by long legal training, they seem to have reached a point where they hold that no other consid- eration is of quite so much importance as the preser- vation of alleged property rights, even when such alleged rights violate the inherent right of the people to live out their individual lives.It is my firm im- pression that sanitary laws can never be properly enforced until a more rigorous method of putting intelligent and conscientious men upon the bench can be devised.
A METHOD OF FACILITATING THE SERUM DIAGNOSIS OF SYPHILIS UNDER WAR CONDITIONS
Authors: Hideyo Noguchi
Journal: JAMA (1918)

<h3>To the Editor:</h3> —Supplementary to the paper with this title, published last week, p. 1157, permit me to add the following suggestion: According to Rhamy (The Journal, Nov. 17, 1917, p. 1728), guinea-pig complement can be preserved in a mixture consisting of 1 part of the fresh guinea-pig serum and 1.5 parts of a 10 per cent, sodium acetate solution in 0.9 per cent, saline for a considerable length of time at room temperature, and the acetate does not interfere with the fixation reaction. The writer has confirmed Rhamy's statement and can add that the same is true of human complement. By mixing fresh serum with the acetate saline solution in equal parts the complement remains perfectly active at room temperature for at least five days, and the results of the tests made with the acetated serums are no different from those obtained with the same specimens in fresh state
Up-regulation of type I procollagen C-proteinase enhancer protein messenger RNA in rats with CCl4-induced liver fibrosis
Authors: I Ogata
Journal: Hepatology (1997)

Using a polyclonal antibody raised against a liver stellate cell (LSC) line derived from a rat CCl4-cirrhotic liver, we isolated 14 clones from a complementary DNA library prepared with total RNA extracted from the same cell line, with nucleotide sequences homologous to that of the type I procollagen C-proteinase enhancer protein (PCPE) gene. The longest PCPE insert of 1,530 base pairs contained an open reading frame coding for 468 amino acids. PCPE cDNA recognized by Northern blot a 1.7-kilobase messenger RNA (mRNA) in total RNA extracted from freshly isolated and early passaged LSC, LSC lines derived from normal (NFSC) and cirrhotic (CFSC) rat livers, and various LSC clones derived from CFSC. The expression of PCPE mRNA was increased threefold in CFSC compared with NFSC. PCPE mRNA was not detected in total rat liver, freshly isolated hepatocytes, or endothelial or Kupffer cells. However, the expression of PCPE mRNA was induced in fibrotic livers of rats treated with CCl4. PCPE mRNA expression in LSC was up-regulated by transforming growth factor β1 (TGF-β1) and down-regulated by tumor necrosis factor α (TNF-α), similar to the changes in α1 (1) procollagen mRNA induced by these cytokines. PCPE was not detectable in liver biomatrix proteins obtained from normal liver. However, PCPE was increased in liver biomatrix proteins from cirrhotic livers and was proportional to the amount of collagen. These data suggest that PCPE may play an important role in the processing of type I collagen during liver fibrogenesis, and that TGF-β1 and TNF-α regulate its expression.