tbuckley/cabot-search huggingface dataset:
Prospects for broad-spectrum chemotherapy of serious viral respiratory infections
Authors: D. S. Fedson
Journal: JAMA (1983)

Physicians are aware of the importance of influenza viruses and respiratory syncytial virus (RSV) as causative agents for severe respiratory illness. Both are responsible for widespread community outbreaks during winter months. Respiratory syncytial virus is the most common cause of serious lower respiratory tract disease in infants and young children. Yet, early in life, both RSV and influenza viruses may be responsible for increases in pediatric hospital admissions.<sup>1,2</sup>In later years, repeated infection with these agents is inescapable. Influenza viruses have long been associated with increased mortality caused by respiratory disease among elderly persons and others with serious underlying medical conditions. However, previous measures of excess mortality may have substantially underestimated their impact. Recent studies have documented the yearly occurrence of community outbreaks of influenza A or B virus infections, each outbreak accompanied by increases in hospital admissions and deaths caused by respiratory disease.<sup>3</sup>There is also a
Abdominal Angiography
Authors: James J. Pollard, Robert A. Nebesar
Journal: New England Journal of Medicine (1968)

Angiography of the Adrenal GlandPlain radiographs of the abdomen, intravenous urograms and retroperitoneal insufflation of carbon dioxide followed by tomography have all been used in the past to study the adrenal glands, but none offer the high diagnostic accuracy obtainable with the angiographic technics currently available. The adrenal glands can be adequately studied by selective injection of contrast medium into either an adrenal artery or into an adrenal vein. Since the adrenal glands receive their blood supply from branches of the inferior phrenic arteries, the aorta and the renal arteries, three separate selective arterial catheterizations are necessary on each . . .
THE PEORIA OUTBREAK
Journal: JAMA (1918)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Iron in enriched wheat flour, farina, bread, buns, and rolls
Journal: JAMA (1972)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Probing The Molecular Structure Of The Voltage-Dependent Sodium Channel
Authors: R. Barchi
Journal: Annual Review of Neuroscience (1988)

The brain's default mode network consists of discrete, bilateral and symmetrical cortical areas, in the medial and lateral parietal, medial prefrontal, and medial and lateral temporal cortices of the human, nonhuman primate, cat, and rodent brains. Its ...Read More
Providers to advise of 'medical Miranda'
Authors: P. Cotton
Journal: JAMA (1991)

HEALTH CARE provider organizations are being ordered to advise patients of their rights to refuse care and to name proxies in case they become incompetent. The so-called medical Miranda warnings, explaining state law on living wills and durable powers of attorney for health care, will be the responsibility of all hospitals, nursing homes, health maintenance organizations (HMOs), hospices, and home health care agencies who want Medicare or Medicaid reimbursement as of November 1991. Officially known as the Patient Self-Determination Act, the law was part of an omnibus budget bill passed last November. It requires that providers Maintain written policies on refusal of care and advance directives Give this written information to adults at the time of admission as hospital inpatients or as residents of a skilled nursing facility, before coming under the care of a home health agency or hospice, or upon enrollment in an HMO Note in patient records
index to advertisers
Journal: JAMA (1988)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Decision aids do improve patients' decision making
Journal: BMJ (1999)

Decision aids do improve patients' decision makingTrials of aids to help patients consider the benefits and harms of medical treatments show that they improve patients' knowledge, comfort, and participation in decision making without increasing anxiety.The systematic review by O'Connor et al (p 731) also found that decision aids had little effect on satisfaction and an inconsistent effect on patients' decisions.The trials of decision aids focused on hormone therapy, circumcision, screening for cancer and genetic disorders, and treatments for prostate cancer, breast cancer, and heart disease.The results consistently showed that decision aids were better than usual practice.
MEDICAL SOCIETY ITEMS.
Journal: JAMA (1883)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Joint Commission Will Collect, Publicize Outcomes
Authors: Andrew A. Skolnick
Journal: JAMA (1993)

STARTING in 1994 after almost a century of stumbling efforts to measure the quality of health care, the US health care industry appears ready to begin measuring provider performance and to make this information available to the public. In May, the board of commissioners of the Joint Commission on Accreditation of Healthcare Organizations (JCAHO), Oakbrook Terrace, Ill, approved a number of policies that will radically change the way that organization surveys and accredits hospitals and other health care organizations. Beginning in January 1994, the joint commission will establish an "indicator monitoring system," which will include a national database for comparing a set of "performance measures" that are designed to rate individual health care providers based on patient outcome. In addition, the commission plans to make many of its findings public, ending a confidentiality policy that critics say protects bad providers. "By making the indicator system operational, the joint commission will
Systematic review of adverse events reporting in clinical trials leading to approval of targeted therapy and immunotherapy
Authors: P. Bossi, L. Botta, P. Bironzo, C. Sonetto, G. Musettini, A. Sbrana, V. Di Giannantonio, L. Locati, M. Di Maio, A. Antonuzzo
Journal: Annals of Oncology (2016)
Takayasu Arteritis
Authors: G S Kerr, C W Hallahan, J Giordano, R Y Leavitt, A S Fauci, M Rottem, G S Hoffman
Journal: Annals of Internal Medicine (1994)

To evaluate prospectively the clinical features, angiographic findings, and response to treatment of patients with Takayasu arteritis.60 patients with Takayasu arteritis were studied at the National Institute of Allergy and Infectious Diseases between 1970 and 1990 and were followed for 6 months to 20 years (median follow-up, 5.3 years).Data on clinical features, angiographic and laboratory findings, disease course, and response to therapy were all recorded and stored in a computer-based retrieval system.The Warren Magnuson Clinical Center of the National Institutes of Health.In our series of patients, Takayasu arteritis was more common in Asian persons compared with persons from other racial groups. Females (97%) were most frequently affected. The median age at disease onset was 25 years. Juveniles had a delay in diagnosis that was about four times that of adults. The clinical presentation ranged from asymptomatic to catastrophic with stroke. The most common clinical finding was a bruit. Hypertension was most often associated with renal artery stenosis. Only 33% of all patients had systemic symptoms on presentation. Sixty-eight percent of patients had extensive vascular disease; stenotic lesions were 3.6-fold more common than were aneurysms (98% compared with 27%). The erythrocyte sedimentation rate was not a consistently reliable surrogate marker of disease activity. Surgical bypass biopsy specimens from clinically inactive patients showed histologically active disease in 44% of patients. Although clinically significant palliation usually occurred after angioplasty or bypass of severely stenotic vessels, restenosis was common. Medical therapy was required for 80% of patients, whereas 20% had monophasic self-limiting disease. Immunosuppressive treatment with glucocorticoids alone or in combination with a cytotoxic agent failed to induce remission in one fourth of patients; about half of those who achieved remission later relapsed.In North America, Takayasu arteritis is a rare disease. It is heterogeneous in presentation, progression, and response to therapy. Current laboratory markers of disease activity are insufficiently reliable to guide management. Most patients require repeated and, at times, prolonged courses of therapy. Although mortality was low, substantial morbidity occurred in most patients.
Circulating tumor cells in locally advanced pancreatic adenocarcinoma: The ancillary study Circe 07 of the LAP 07 trial.
Authors: Florence Huguet, François-Clément Bidard, Christophe Louvet, Laurent Mineur, Olivier Bouche, Benoist Chibaudel, Pascal Artru, Françoise Desseigne, Jean-Baptiste Bachet, Mohamed Gasmi, Suzanne Nguyen, Lionel Wander, Claire Mathiot, Jean-Yves Pierga, Pascal Hammel
Journal: Journal of Clinical Oncology (2013)

188 Background: Pancreatic carcinoma is one of the leading causes of cancer-related mortality. At time of diagnosis, 30% of patients present with a locally advanced unresectable but non metastatic carcinoma (LAPC). Theoretically, patients with micrometastatic dissemination at diagnosis should benefit from systemic treatments, whereas radiation therapy should be favored in the others. Based on the hypothesis that circulating tumor cells (CTC) count is a surrogate of the cancer metastatic abilities, CTC detection rates and prognostic value were studied in a prospective cohort of LAPC patients. Methods: LAP07 international multicenter randomized study assesses in patients whose LAPC is controlled after 4 months of gemcitabine-based chemotherapy whether to administrate a chemoradiotherapy could increase overall survival versus continuation of chemotherapy alone. A subgroup of patients included in LAP 07 trial were prospectively screened for CTC before the start of the chemotherapy and after two months of treatment, using the CellSearch technique. Clinico-pathological characteristics and survival of patients were obtained prospectively and were correlated with CTC detection. Results: Seventy-nine patients were included in this ancillary study. One or more CTC/7.5ml were detected in 5% of patients before treatment and in 9% of patients after two months of chemotherapy (overall detection rate: 11% of patients). CTC positivity was associated with poor tumor differentiation (p=0.04), and with shorter overall survival in multivariable analysis (RR=2.5, p=0.01), together with anemia (p=0.005). Conclusions: The evaluation of micrometastatic disease using CTC detection appears as a promising tool which could help to personalize treatment modalities in LAPC patients. Clinical trial information: CDR0000589283.
Financing Long-term Care
Authors: Janet Weiner
Journal: JAMA (1994)

THE United States is poised on an ethical precipice as it deliberates health system reform. As the debate continues about revolutionary changes in the organization and financing of health care, the following dilemma arises: can the long-term care needs of the chronically ill and disabled be included, without dooming the reform itself to political and financial failure? In 1991, the United States spent $59.9 billion on nursing home care (about 8% of total health care expenditures)<sup>1</sup>and $9.8 billion (1% of national health spending) on formal home health services (services provided by non-facility-based agencies). The reluctance to include long-term care in health system reform stems not from the magnitude of present expenditures, but rather from the anticipation of rapidly rising expenditures in the foreseeable future. Home health care is the fastest growing component of personal health care spending, having risen sevenfold in the last decade and 29% from 1990
Accepted Dental Remedies Containing a List of Official Drugs Selected to Promote a Rational Dental Materia Medica and Descriptions of Acceptable Nonofficial Articles, 1934
Journal: JAMA (1935)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Free Papers
Authors: V. Cerny, P. Zivny, P. Dostal, L. Zabka, R. D. Griffiths, T. E. A. Palmer, C. Jones, S. Atkinson, E. Sieffert, D. Bihari, B. J. Morlion, H. P. Siedhoff, P. Fürst, C. Puchstein, F. Sultan, D. Lagrange, M. Boisset, M. -I. Malewiak, M. Braga, L. Gianotti, A. Cestari, A. Vignali, F. Pellegatta, V. Di Carlo, I. Michel, A. Dive, M. Stoffel, L. Galanti, J. Jamart, Et. Installé, R. Chiolero, C. Cayeux, Ph. Schneiter, J. M. Schwarz, L. Tappy, E. Kourias, Th. Theodosopoulos, A. Datsis, J. Vassiliou, B. Smyrniotis, A. Weimann, L. Bastian, W. E. Bischoff, M. Grotz, S. Bode-Böger, M. Hansel, J. Lotz, G. Regel, M. Senkal, M. Kernen, U. Eickhoff, A. Mumme, V. Zumtobel, E. Kollig, P. Wachtler, M. Koeller, G. Wolfram
Journal: Intensive Care Medicine (1996)
YELLOW FEVER AS A CONTROLLABLE DISEASE.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Books Received
Journal: JAMA (1927)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Single cell RNA-seq of patient liver tissues uncover HRH2+/CLEC5a high/macro low macrophages as therapeutic target for the treatment of liver fibrosis and cancer prevention
Authors: Emilie Crouchet, Simonetta Bandiera, Naoto Fujiwara, Shen Li, Hussein El Saghire, Xiaochen Sun, Hadassa Hirschfield, Natascha Roehlen, Frank Jühling, Antonio Saviano, Victor Gonzalez-Motos, Anu Venkatesh, Clara Ponsolles, Joachim Lupberger, François H.T. Duong, Shijia Zhu, Mozhdeh Sojoodi, Ricard Masia, Lan Wei, Marine Oudot, Sarah Durand, Shigeki Nakagawa, Atsushi Ono, Won-Min Song, Takaaki Higashi, Rosa S. Kim, C Billie Bian, Tom Croonenborghs, Raymond Chung, Danijela Heide, Jenny Hetzer, Beate Straub, Detlef Schuppan, Anna P. Koh, Milind Mahajan, Mathias Heikenwalder, Emanuele Felli, Patrick Pessaux, Kenneth K. Tanabe, Catherine Schuster, Nathalie Pochet, Mirjam Zeisel, Bryan C. Fuchs, Yujin Hoshida, Thomas Baumert
Journal: Journal of Hepatology (2020)
Protecting human subjects of biomedical research
Authors: C. Marwick
Journal: JAMA (1997)

CONGRESS and the White House are weighing tighter measures to protect human subjects of biomedical research. At issue is adherence to the so-called common rule. The common rule is the core of the regulations governing research on human subjects; essentially, it requires that agencies engaged in such research set up committees to review research proposals for possible risk or harm (<i>JAMA</i>. 1996;276:1627). The common rule sets out the requirements for informed consent and institutional review board oversight. It has been adopted by 17 federal departments and agencies that conduct or sponsor biomedical and behavioral research on humans. Addressing a meeting of the National Bioethics Advisory Commission, Chris Kline, a staff member of the US Senate Committee on Governmental Affairs, said the committee is preparing legislation that would require all government agencies to adhere to the common rule. The legislation would stipulate criminal sanctions for violations. The White House is preparing