Theophylline Therapy for Near-Fatal Cheyne-Stokes Respiration
Authors: Edgar J. Geigel, Alejandro D. Chediak
Journal: Annals of Internal Medicine (1999)

Letters2 November 1999Theophylline Therapy for Near-Fatal Cheyne-Stokes RespirationEdgar J. Geigel, MD and Alejandro D. Chediak, MDEdgar J. Geigel, MDMount Sinai Medical Center; Miami Beach, FL 33140 (Geigel)Mount Sinai Medical Center; Miami Beach, FL 33140 (Chediak)Search for more papers by this author and Alejandro D. Chediak, MDMount Sinai Medical Center; Miami Beach, FL 33140 (Geigel)Mount Sinai Medical Center; Miami Beach, FL 33140 (Chediak)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-131-9-199911020-00019 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Pesek and colleagues (1) reported a very interesting case of periodic central apneas responding acutely to theophylline. However, we take exception to using the term “Cheyne-Stokes respiration” to describe the pattern of breathing in this case. Cheyne-Stokes respiration is a form of periodic breathing in which hyperpnea and hypopnea oscillate cyclically. Apnea can accompany the hypopneic phase of the disorder (2, 3). In contrast to other patterns of periodic breathing, the transition between hyperpnea and hypopnea are gradual and have a crescendo-decrescendo appearance (2). Cheyne-Stokes respiration is found most often in patients with congestive heart failure, where ...References1. Pesek CA, Cooley R, Narkiewicz K, Dyken M, Weintraub NL, Somers VK. Theophylline therapy for near-fatal Cheyne-Stokes respiration. A case report. Ann Intern Med. 1999;130:427-30. LinkGoogle Scholar2. Hanly P, Zuberi N, Gray R. Pathogenesis of Cheyne-Stokes respiration in patients with congestive heart failure. Relationship to arterial Pco 2 . Chest. 1993;104:1079-84. CrossrefMedlineGoogle Scholar3. Ancoli-Israel S, Engler RL, Friedman PJ, Klauber MR, Ross PA, Kripke DF. Comparison of patients with central sleep apnea: with and without Cheyne-Stokes respiration. Chest. 1994;106:780-6. CrossrefMedlineGoogle Scholar4. Javaheri S, Parker TJ, Wexler L, Liming JD, Lindover P, Roselle GA. Effect of theophylline on sleep-disordered breathing in heart failure. N Engl J Med. 1996;335:562-6. CrossrefMedlineGoogle Scholar5. Javaheri S, Corbett WS. Association of low Paco 2 with central sleep apnea and ventricular arrhythmias in ambulatory patients with stable heart failure. Ann Intern Med. 1998;128:204-7. LinkGoogle Scholar Author, Article, and Disclosure InformationAuthors: Edgar J. Geigel, MD; Alejandro D. Chediak, MDAffiliations: Mount Sinai Medical Center; Miami Beach, FL 33140 (Geigel)Mount Sinai Medical Center; Miami Beach, FL 33140 (Chediak) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoTheophylline Therapy for Near-Fatal Cheyne–Stokes Respiration: A Case Report Catherine A. Pesek , Ryan Cooley , Krzysztof Narkiewicz , Mark Dyken , Neal L. Weintraub , and Virend K. Somers Theophylline Therapy for Near-Fatal Cheyne-Stokes Respiration Virend K. Somers and Catherine Pesek Theophylline Therapy for Near-Fatal Cheyne-Stokes Respiration Don D. Sin and T. Douglas Bradley Metrics 2 November 1999Volume 131, Issue 9 Page: 713-714 Keywords Apnea Breathing Diazepam Heart failure Medical dialysis Renal failure Respiration Sleep apnea Tidal volume ePublished: 15 August 2000 Issue Published: 2 November 1999 Copyright & PermissionsCopyright © 1999 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...