tbuckley/cabot-search huggingface dataset:
E. BOUCHUT.
Journal: JAMA (1892)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Poster Session 1
Authors: C Cassidy, Hintescu Togoe, C Sinescu, M Shochat, A Shotan, D Blondheim, M Kazatsker, A Asif, I Shochat, I Dahan, Y Levy, L Vasilenko, ; Meisel, M Boulogne, ; Sadoune, J Launay, ; Boirau, ; Laribi, A Solal, ; Logeart, B Fbruno, Filipe Lourenco, D Moreira, A Delgado, L Abreu, J Pereira, Oliveira Santos
Journal: European Journal of Heart Failure (2014)
Clinical Summaries
Journal: Circulation (2009)

Incidence and Risk Factors of Arrhythmic Events in Catecholaminergic Polymorphic Ventricular TachycardiaCatecholaminergic polymorphic ventricular tachycardia is a rarely recognized but important cause of sudden cardiac death in the young.This multicenter observational study of 101 subjects (50 probands, 51 family members) was conducted to characterize the clinical course of the disease.Catecholaminergic polymorphic ventricular tachycardia was diagnosed from clinical features in 84 subjects and from genotyping in 17 subjects.During the follow-up of 7.9Ϯ4.9years, 27 patients (27%), including 2 silent gene mutation carriers, experienced syncope, aborted cardiac arrest, or sudden cardiac death events that were fatal or near-fatal in 13 subjects.The estimated 8-year event rate was 32% with a 13% rate of fatal or near-fatal events.The event rates between the probands and family members were comparable.A younger age at diagnosis, a history of aborted cardiac arrest, and the absence of ␤-blockers were predictors of events, but ␤-blocker therapy was not completely protective.These results suggest that ␤-blockers should be prescribed even if the diagnosis is made from genotyping when there is not a history of symptomatic arrhythmias.Additional therapies, including implantable defibrillators, verapamil, or left cardiac sympathetic denervation, should be considered in patients with markers of increased risk.See p 2426.
SMALLPOX AND VACCINATION IN PORTO RICO.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Growth of Medical Literature
Journal: JAMA (2013)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A Practical Manual of Insanity. For the Medical Student and General Practitioner. By Daniel R. Brower, A. M., M. D., LL. D., Professor of Nervous and Mental Diseases in Rush Medical College, in Affiliation with the University of Chicago, Professor of Nervous and Mental Diseases in the Woman's Medical School of the Northwestern University, and in the Post-Graduate Medical School of Chicago; and Henry M. Bannister, A. M., M. D., formerly Senior Assistant Physician, Illinois Eastern Hospital for …
Journal: American Journal of Psychiatry (1902)
TB’s Disproportionate Effect on Foreign-Born US Residents
Journal: JAMA (2014)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Delayed antibiotic prescribing for respiratory tract infections: individual patient data meta-analysis
Journal: BMJ (2021)

results reported in the abstract for symptom severity should have been "No difference was found in follow-up symptom severity (seven point scale) for delayed versus no antibiotics (adjusted mean difference -0.003, 95% confidence interval -0.12 to 0.11) or delayed versus immediate antibiotics (0.02, -0.11 to 0.15).
Drug Ill Effects on the Skin
Journal: BMJ (1974)

announced, as well as £32,600 as three-year support from the Department of Health for the department of psychological medicine's psycho-geriatric research programme.Eyes at the Westminster Just 250 years ago William Cheselden per- formed the first ophthalmic operation to be done in the then recently opened Westminster Hospital.The leading oculist of his day thus began an unbroken succession of eye surgery at the Westminster.Four years after Cheseldens' arrival Thomas Hope was also ap- pointed oculist to the hospital, so that 50% of the consultant surgeons there were then opthalmologists.These and later events are commemorated in a pamphlet produced priv- ately by Mr. P. Trevor-Roper, consulting ophthalmic surgeon to the hospital.
The Value of Upper Gastrointestinal Endoscopy
Authors: Richard R. Babb
Journal: JAMA (1973)

Upper gastrointestinal endoscopy is a valuable aid in the diagnosis of mucosal diseases involving the stomach and duodenum. Technical advances in the design of fiber optic equipment<sup>1</sup>combined with increasing physician experience in their use have led to a safe and accurate procedure that can be accomplished quickly with only minimal discomfort to the patient. Visualized lesions are accessible to biopsy, and can be documented for future reference with still or movie photography. A series of recent articles shows the importance of endoscopy in the evaluation of patients with diverse gastrointestinal symptoms who have normal results from barium studies of the stomach and duodenum. This is a common problem in the everyday practice of medicine. Schuman<sup>2</sup>reviewed the gastroscopic findings in 843 patients with persistent complaints and normal upper-gastrointestinal x-ray films. One hundred sixty-three, or 20%, were found to have mucosal diseases, including 59 patients with ulcers and
EMOTIONAL REACTIONS TO LONG-TERM ANTICOAGULANT THERAPY
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Evaluation of an ELISA system for determination of class-specific antibodies to native and denatured DNA in man
Journal: Annals of the Rheumatic Diseases (1986)

The authors set out to review such clinical trials as have been conducted in the rheumatic diseases.Individual chapters are devoted to trials in osteoarthritis, rheumatoid arthritis, juvenile arthritis, seronegative arthritides, crystal arthritis, systemic lupus erythematosus, and low back pain.In addition, there is a useful preliminary chapter on methodological considerations in clinical trials and a final chapter which includes a proposal for a system by which the design, execution, and analysis of trials may be coded so as to improve reporting and interpretation of trials.
Injuries and Diseases of the Jaws.
Authors: None E. W. A.
Journal: JAMA (1884)

The third edition of this standard treatise is not markedly changed in form or in size. It is, upon the whole, more carefully written, and contains a chapter on Diseases of the Temporo-Maxillary Articulation, which is a new topic. Tumors of the jaws are far more intelligently and satisfactorily classified in this edition, and this whole important subject is revised in the light of recent pathological research. In other words, microscopical study of the various new growths of the jaws is made the basis of their classification. Chapters XIV to XXV—nearly one-half the entire work—are devoted to the various tumors of the gums and jaws. This constitutes the portion of the book to which the general surgeon would turn for special information. Specialists in oral surgery, aside from mere dentistry, are now to be found in the larger cities. This is not a work on dental surgery. A chapter on
PREFACE
Authors: Arthur Rook, R. H. Champion
Journal: British Journal of Dermatology (1969)

Journal Article PREFACE Get access Arthur Rook, Arthur Rook Search for other works by this author on: Oxford Academic Google Scholar R. H. Champion R. H. Champion Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 81, Issue s3, 1 June 1969, Page 1, https://doi.org/10.1111/j.1365-2133.1969.tb12846.x Published: 01 June 1969
Book Review A Primer for Diabetic Patients: An outline of treatment for diabetes with diet, insulin and protamine-zinc insulin, including directions and charts for the use of physicians in planning diet prescriptions . Seventh edition, reset. By Russell M. Wilder, M.D. 12°, cloth, 184 pp., with 11 tables, 7 illustrations and 1 plate. Philadelphia: W. B. Saunders Company, 1941. $1.75.
Journal: New England Journal of Medicine (1942)
Presence of Bisphenol A and Parabens in a Neonatal Intensive Care Unit: An Exploratory Study of Potential Sources of Exposure
Authors: Luz M. Iribarne-Durán, Francisco Artacho-Cordón, Manuela Peña-Caballero, José M. Molina-Molina, Inmaculada Jiménez-Díaz, Fernando Vela-Soria, Laura Serrano, José A. Hurtado, Mariana F. Fernández, Carmen Freire, Nicolás Olea
Journal: Environmental Health Perspectives (2019)

Background: Newborns in neonatal intensive care units (NICUs) are in contact with a variety of medical products whose production might include synthetic chemicals with hormonal activity. Objectives: Our aim was to assess the content of bisphenol A (BPA) and parabens (PBs) and the hormone-like activities of a subset of medical products commonly used in NICUs in prolonged intimate contact with NICU newborns. Methods: Fifty-two NICU items were analyzed, determining the concentrations of BPA and PBs [methyl- (MeP), ethyl- (EtP), propyl- (PrP), and butylparaben (BuP)] and using the E-Screen and PALM-luciferase assays to measure the in vitro (anti-)estrogenic and (anti-)androgenic activity, respectively, of the extracts. Items found to have elevated BPA/PB content or hormone-like activities were further extracted using leaching methodologies. Results: BPA was found in three-fifths and PBs in four-fifths of tested NICU items, and ∼25% and ∼10% of extracts evidenced estrogenic and anti-androgenic activity, respectively. The highest BPA content was found in the three-way stopcock (&gt;7.000 ng/g), followed by patterned transparent film dressing, gastro-duodenal feeding tubes, sterile gloves, single-lumen umbilical catheters, and intravenous (IV) infusion extension sets (concentrations ranged from 100 to 700 ng/g BPA). A total PB concentration (∑PBs) &gt;100 ng/g was observed in several items, including light therapy protection glasses, patterned transparent film dressing, winged IV catheters, IV infusion extension sets, and textile tape. The highest estrogenic activity [&gt;450 pM estradiol equivalent (E2eq)] was found in small dummy nipples, three-way stopcocks, and patterned transparent film dressing and the highest anti-androgenic activity [&gt;5 mM procymidone equivalent units per gram (Proceq/g)] in small dummy nipples and three-way stopcocks. Discussion: According to these findings, neonates might be exposed to multiple sources of BPA and PBs in NICUs via inhalation, dermal, oral, and IV/parenteral routes. There is a need to address the future health implications for these extremely vulnerable patients and to adopt precautionary preventive measures as a matter of urgency. https://doi.org/10.1289/EHP5564
Abstract 2552: Senescence induced by CDK4/6 inhibition facilitates anti-tumor T cell responses
Authors: Ashlyn Blevins, Stacey Mont, Hunter Lawrence, Nabil Saleh, Sheau-Chiann Chen, Ann Richmond, Anna Vilgelm
Journal: Cancer Research (2019)

Abstract Cancer immunotherapies have shown remarkable clinical activity across several tumor types but responses have been modest in breast cancers. This is attributed to low levels of neo-antigens in breast tumors and immunosuppressive nature of mammary tumor microenvironment. Here we investigated if we can counteract these obstacles to an effective immunotherapy by inducing senescence in breast cancer cells. Senescence is one of the physiological stress response programs characterized by loss of proliferative potential and secretion of a variety of pro-inflammatory markers which promotes identification and removal of senescent cells by the immune cells. Here we hypothesized that senescence will stimulate anti-tumor immune response by establishing immune-permissive microenvironment. We utilized immunocompetent and humanized PDX-bearing mice to investigate senescence-induced modulation of tumor secretome proteome, transcriptome and immune cell recruitment and activity. An FDA-approved small molecule CDK4/6 inhibitor was used to induce senescence. We detected induction of multiple markers of senescence after CDK4/6 inhibitor treatment of cells and tumors. Senescent cells and tumors had increased secretion of chemokines CCL4, CCL5, CXCL9, CXCL10 and CXCL11 which facilitated T cell homing into the tumor. This was a result of their transcriptional induction by NF-κB. Consequently, we observed the dynamic enrichment of tumor immune microenvironment with T cells in tumors treated with CDK4/6 inhibitor. Furthermore, the recruitment of adoptively transferred ex-vivo activated anti-tumor T cells was significantly enhanced in tumors that were treated with CDK4/6 inhibitor. Finally, CDK4/6 inhibitor-treated tumors became responsive to T cell-activating immunotherapy with antibody agonists of T cell co-stimulatory receptors OX40 and 4-1BB. In summary, our findings suggest that CDK4/6 inhibition can facilitate T cell recruitment into the mammary tumors which can lead to an improved immunotherapy response. This pre-clinical study provides rationale for clinical development of CDK4/6 inhibitors and T cell agonists and uncovers the potential of senescence-inducing approach for sensitizing tumors to immune therapy. Citation Format: Ashlyn Blevins, Stacey Mont, Hunter Lawrence, Nabil Saleh, Sheau-Chiann Chen, Ann Richmond, Anna Vilgelm. Senescence induced by CDK4/6 inhibition facilitates anti-tumor T cell responses [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 2552.
Questions and Answers
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
LONDON
Journal: JAMA (1927)

<h3>Preservatives in Food: New Regulations</h3> New responsibilities are placed on the manufacturers and purveyors of foodstuffs by the regulations that come into force in 1927. For the purpose of the regulations, "preservative" means any substance capable of inhibiting, retarding or arresting the process of fermentation, acidification or other decomposition of food, or of masking any of the evidences of putrefaction; but does not include sodium chloride, sodium or potassium nitrate, sugars, acetic acid or vinegar, glycerin, alcohol or potable spirits, herbs, hop extract, spices and essential oils used for flavoring purposes, or any substance added to food by the process of curing known as smoking. Cream must not contain any "thickening substance" (which means sucrate of lime, gelatin, starch paste, or any other substance that does not include cane or beet sugar). Preservative and coloring matters which are specified in a schedule are forbidden except as shown in the following
Flow cytometric analysis of T and Tn epitopes on chronic lymphocytic leukemia cells
Authors: Cynthia Timlick Aller, Omer Kucuk, Georg F. Springer, Alice Gilman‐Sachs
Journal: American Journal of Hematology (1996)

Immunophenotyping of peripheral blood lymphocytes from six patients with B-cell chronic lymphocytic leukemia (B-CLL) and five normal volunteers was done and their T and Tn epitopes analyzed using specific monoclonal antibodies and flow cytometry. Lymphocytes from all patients showed strong Tn expression as compared to normal control lymphocytes. By contrast, T antigen was not expressed. The Tn expression may be a useful diagnostic and prognostic marker for B-CLL. © 1996 Wiley-Liss, Inc.
Orthopedic Surgery.
Journal: JAMA (1930)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Transcatheter closure of atrial septal defects and patent foramen ovale under intracardiac echocardiographic guidance: Feasibility and comparison with transesophageal echocardiography Ziyad M. M. H. Hijazi, Zhong Wang, Qi-Ling Cao, Peter Koenig, David Waight, Roberto Lang. University of Chicago Children's Hospital, Chicago, IL
Journal: Journal of the American College of Cardiology (2001)