tbuckley/cabot-search huggingface dataset:
Postoperative Hyponatremia
Authors: Mitchell Halperin
Journal: Annals of Internal Medicine (1997)

Letters15 June 1997Postoperative HyponatremiaMitchell Halperin, MD, FRCP(C), Manjula Gowrishankar, MD, FRCP(C), and C. David Mazer, MD, FRCP(C)Mitchell Halperin, MD, FRCP(C)University of Toronto, Toronto, Ontario M5B 1A6, CanadaSearch for more papers by this author, Manjula Gowrishankar, MD, FRCP(C)University of Toronto, Toronto, Ontario M5B 1A6, CanadaSearch for more papers by this author, and C. David Mazer, MD, FRCP(C)University of Toronto, Toronto, Ontario M5B 1A6, CanadaSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-126-12-199706150-00031 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:Ayus and Arieff's letter deserves clarification on three points.First, can the plasma sodium level decrease to 120 mmol/L if only isotonic saline was infused? It is universally agreed that severe hyponatremia must be avoided immediately after surgery. Anything that adds electrolyte-free water (for example, hypotonic infusions or desalination of isotonic saline) when antidiuretic hormone acts contributes to the degree of hyponatremia and should be minimized. Moreover, the amount given relative to body size is important. A calculation might help here. Almost 15% of total body water must be retained as electrolyte-free water to cause the plasma sodium ...REFERENCE1. Welt LG, Orloss J, Kydd DM, Oltman JE. An example of cellular hyperosmolarity. J Clin Invest. 1950; 29:935-9. Google Scholar Author, Article, and Disclosure InformationAuthors: Mitchell Halperin, MD, FRCP(C); Manjula Gowrishankar, MD, FRCP(C); C. David Mazer, MD, FRCP(C)Affiliations: University of Toronto, Toronto, Ontario M5B 1A6, Canada PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 15 June 1997Volume 126, Issue 12Page: 1006KeywordsAntidiuretic hormoneBlood plasmaBody fluidsBrainBrain diseasesEpileptic seizuresHyponatremiaIsotonicitySodiumSurgery ePublished: 15 August 2000 Issue Published: 15 June 1997 Copyright & PermissionsCopyright © 1997 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Liver cell adenoma and oral contraceptives. Double tumor development
Authors: K. Antoniades
Journal: JAMA (1975)

A POSSIBLE association between liver cell adenoma and oral contraceptives has been indicated in recent reports.<sup>1-10</sup>Although histologically benign, these tumors can be complicated by rupture, bleeding, hemoperitoneum, and shock. Death has occurred in eight of 24 cases reported to date. It is likely that an increasing number of these tumors will manifest themselves in the future. To our knowledge, this is the first report of a case in which completely separate tumors of the liver were found simultaneously in a patient taking oral contraceptives. This is the second case involving liver cell adenoma seen within a year at our institution.<sup>10</sup> <h3>Report of a Case</h3> A 32-year-old woman, gravida 3, para 3, had been taking oral contraceptives (a mixture of norethindrone and mestranol [Ortho-Novum], 2 mg) for six years. She was admitted to our hospital with upper abdominal pain associated with nausea and vomiting of a few days'
Leeward Passage
Authors: Herbert I. Kallet
Journal: JAMA (1972)

<h3>To the Editor.—</h3> In a letter in the July 17th issue ofThe Journal, Drs. Johnson and Parker report the passage of a thermometer through the gastrointestinal tract (221:303, 1972). They note that the passage was expedited by eating a high residue diet. Many years ago, a carpenter was referred to me because he had swallowed a nail of similar size and shape as that of a thermometer. It had been his custom while working on a ladder to hold nails between his teeth. Somehow the ladder had slipped and in his effort to right himself, he gulped— swallowing a nail. His industrial physician followed the progress of the nail by x-ray film. It reached the sigmoid, but after ten days still remained there. He was referred to me at that time for its removal. Its location, however, was too high for extraction through a sigmoidoscope. I was anxious to
Urothelial Carcinoma
Authors: Conan So, M Minhaj Siddiqui
Journal: New England Journal of Medicine (2018)

A 69-year-old woman presented to the emergency department with gross hematuria. Cystoscopic examination of the bladder (shown in a video) revealed a papillary mass protruding through the ureteral orifice with ureteral peristalsis.
Cytokines: Introduction
Authors: R M du Bois
Journal: Thorax (1993)

The catestatin fragment of chromogranin A is the first known endogenous compound able to inhibit catecholamine release elicited by the activation of neuronal nicotinic acetylcholine receptors (nAChRs) of different animal species and catecholaminergic cell types. However, how catestatin regulates the receptor activity, which subunit combination of the heteropentameric forms of receptor is better blocked by the peptide, or how it affects the different stages of the exocytotic process have not yet been evaluated. To address these questions, we have assayed the effects of catestatin: (first) on the inward currents elicited by ACh (<i>I</i><sub>ACh</sub>) in voltage-clamped oocytes expressing different combinations of nAChR subunits; and (second) on the cytosolic Ca<sup>2+</sup> concentration, [Ca<sup>2+</sup>]<sub>c</sub>, and quantal release of catecholamines simultaneously monitored in single adrenal chromaffin cells stimulated with ACh. Catestatin potently blocks all the subtypes of nAChRs studied. Furthermore, it inhibits the α<sub>3</sub>β<sub>4</sub> current in a reversible, noncompetitive, voltage-, and use-dependent manner, a behavior compatible with open-channel blockade. In fura-2-loaded single chromaffin cells, the peptide reduced the [Ca<sup>2+</sup>]<sub>c</sub> signal and the total release of catecholamines elicited by ACh; however, catestatin did not modify the kinetics or the last step of the exocytotic process. Our results suggest that catestatin might play an autocrine regulatory role in neuroendocrine secretion through its interaction with different native nAChR subtypes; the extent of receptor blockade by the peptide could be acutely regulated by the intensity and duration of the presynaptic stimulus.
Introduction
Authors: Darla Danford
Journal: Annals of Internal Medicine (1993)

Methods for Voluntary Weight Loss and Control: National Institutes of Health Technology Assessment Conference1 October 1993IntroductionDarla Danford, DSc, MPH, RD and Suzanne W. Fletcher, MD, EditorDarla Danford, DSc, MPH, RDSearch for more papers by this author and Suzanne W. Fletcher, MD, EditorSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-119-7_Part_2-199310011-00002 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail A health paradox exists in modern America. On the one hand, many people who do not need to lose weight are trying to. On the other hand, most who do need to lose weight are not succeeding. The percentage of Americans whose health is jeopardized by too much weight is increasing.So begins the statement of the Technology Assessment Panel convened for the National Institutes of Health (NIH) Technology Assessment Conference on Methods for Voluntary Weight Loss and Control. This supplement issue of Annals contains papers presenting the scientific data on which the panel relied to reach its conclusions, as ... Author, Article, and Disclosure InformationAuthors: Darla Danford, DSc, MPH, RD; Suzanne W. Fletcher, MD, Editor PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byExploring the Association Between Body Weight, Stigma of Obesity, and Health Care Avoidance 1 October 1993Volume 119, Issue 7_Part_2Page: 642KeywordsBody weightDrugsEpidemiologyExerciseInformation storage and retrievalLongitudinal studiesObesityPeer reviewPopulation statisticsWeight loss ePublished: 15 August 2000 Issue Published: 1 October 1993 Copyright & PermissionsCopyright © 1993 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Diseases of the Chest, Chicago
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Error in Phthalate Metabolite Name
Authors: Diane Feskanich, Walter Willett
Journal: JAMA Pediatrics (2014)

Dr Howland concluded that our results are invalid owing to method limitations, including confounding by adult risk factors for hip fractures that were not in our statistical models.However, these factors would only confound our results if they were also associated with adolescent milk consumption, which is unlikely.As shown in the Table in our article, adult behaviors related to fracture risk including smoking, physical activity, and use of various medications were not associated with adolescent milk intake and adjusting for these factors had no effect on our findings.Adolescent milk intake was associated with adult milk intake and adjusting for this also had no appreciable effect.Dr Howland was critical of our statement that height is a known risk factor for hip fracture (confirmed by Dr Heaney) and therefore it could not be an intermediate variable.He referenced a relatively small study (309 hip fractures) by Compston et al 3 with a nonsignificant association; however, the 9 other studies cited in that study all reported significant positive associations between height and hip fracture incidence.This association is not weak, as an 8-inch difference in height translates to approximately a doubling of risk of hip fracture.Lastly, Dr Howland concluded that the error in retrospective reporting of milk consumption during teenage years by older adults rendered our results invalid.Although some aspects of diet in the distant past may be poorly recalled, whether milk is infrequently consumed or consumed multiple times a day is more likely to be remembered.The validity of reported adolescent milk intake in our study was directly supported by the positive association with attained height, which is consistent with our earlier prospective findings on current milk intake among adolescents. 4 Random error in exposure assessment tends to attenuate a true association toward the null, yet we observed a positive association between teenage milk consumption and hip fracture in men.In conclusion, observational epidemiologic studies like ours can contribute useful information, and often the only available direct information, on topics of great public health importance.Specifically, our findings suggest a partial explanation for the long-standing enigma that hip fracture rates are highest in populations with the greatest milk consumption and that further research in this area is needed.
Gastrointestinal bleeding
Authors: P. Eisendrath, O. Le Moine
Journal: Endoscopy (2009)

For this year’s Endoscopy Essentials installment of gastrointestinal bleeding, we have selected important papers in the field of nonvariceal and variceal-related digestive bleeding. Many questions regarding the general and endoscopic management of these patients have remained, up to now, unanswered. The past year has been very prolific in providing us with good-quality randomized trials as well as well-conducted meta-analyses in hot topics in the field. We hope that these studies, will eventually clarify and standardize the management of patients with digestive bleeding and promote new fields of research in endoscopy.
Author's reply
Authors: A D Blann
Journal: Annals of the Rheumatic Diseases (1993)

Temporal artery from a patient with arteritis temporalis.Immunoperoxidase and counterstaining with haematoxylin.Von Willebrandfactor antigen was localised in endothelial cells ofthe vessel and in large amounts in newv vessels along the lamina elastca.there are no signs of damage to-the endo- thelium, and have shown2 that intense production of vWFAg occurs in the many new vessels occurring in the inflammatory infil- trates (figure).The figure also shows the presence of vWFAg as a slight immuno- peroxidase staining in endothelium cells.This staining pattern is not different from the pattern seen in normal temporal arteries or in biopsy specimens from patients with polymyalgia rheumatica and normal levels of vWFAg.As similar microvascular abnor- malities (the introduction ofmany new vessels) are present in most of the diseases with increased vWFAg mentioned above, the reliability of raised levels of vWFAg in these diseases, including Sjogren's syndrome, as a marker of endothelial damage should be reconsidered.
&lt;TITLE&gt;Alcohol Use and Heart Disease&lt;/TITLE&gt;
Journal: JAMA (2001)

There are many changes you can make to lower your risk of heart disease.You can keep your heart healthy by participating in regular physical activity, eating a healthy diet, maintaining a healthy weight, and by reducing excess stress.Moderate alcohol consumption also appears to lower the risk of experiencing certain complications of heart disease.However, you must weigh the benefits and risks associated with alcohol use.Consult your doctor.He or she can help you with this decision.An article in the April 18, 2001, issue of JAMA reports a study that found that moderate alcohol consumption was associated with a decreased risk for older adults (study participants were 65 or older) of experiencing heart failure, which occurs when the heart does not pump efficiently.Another study in the same issue of JAMA found that light (less than 7 alcoholic drinks per week) and moderate alcohol consumption in the year before experiencing a myocardial infarction (a "heart attack") was associated with a reduced risk of death.
Council on Physical Therapy
Journal: JAMA (1930)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Commonly used non-invasive markers do not reliably predict liver fibrosis in those patients of chronic hepatitis B who really need it: a prospective multi-centre study
Authors: Akash Shukla, Amit Gupte, Alisha Chaubal, Prashant Dhore, Suhas Udgirkar, Rahulkumar Jadhav, Abhishek Sadalage, Ravi Thanage, Prabha sawant, Pravin Rathi, Shobna Bhatia
Journal: Journal of Hepatology (2020)
Brand names.
Journal: BMJ (1968)

PointersTreating Myocardial Infarction: Analysis of 150 patients treated in the intensive care unit at Hammersmith Hospital showed overall mor- tality of 19%.Life-threatening arrythmias often occurred more than three days after infarc- tion (p.787).Arrhythmias and resuscitation satisfactorily coped with in a relatively simple coronary care unit in a general hospital (p.830).Leader at p. 782.Screening for Glaucoma: Tonometry is best single test, and survey in Bedford revealed that 80% of those with glaucoma were over 60 and :hat over 10% of population screened required further investigation (p.791).Slimming and Sleep: Comparison of diethylpropion and fenfluramine showed that only the former caused frequent awakening and suppres- sion of paradoxical sleep (p.796).Iron Absorption: Acute liver disease lowers absorption of iron, and administration of pan- creatic extract did not affect this (p.799).
Hepatitis From Ear Piercing
Authors: Alan E. Van Sciver
Journal: JAMA (1969)

<h3>To the Editor:—</h3> I have a young patient who recently contracted hepatitis. The patient admits to the occasional use of marijuana, but denies any and all use of injectable drugs. None of her acquaintances has hepatitis or has had it recently. After repeated questioning for any puncturing of the skin such as the Amerind custom of "blood brothers," she remembered that she had had her ears pierced two or three months ago in the jewelry store where she worked. The day after piercing, one of the earrings fell out. The patient then tried several others until she found a pair she liked, which she then purchased. (I had told her that when I pierced ears, I insisted on autoclaving the earrings first, and that the same pair remain in the ears for a full month.) Oh, yes, the technique for piercing: The operator has a "punch" which he uses to
OBESITY AND DIABETES
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Transactions Illinois State Medical Society.
Journal: JAMA (1893)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
'Medical Alert' for Witnesses
Journal: JAMA (1981)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Nervous Breakdowns and How to Avoid Them.
Journal: JAMA (1913)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal