tbuckley/cabot-search huggingface dataset:
Preliminary Incidence and Trends of Infections with Pathogens Transmitted Commonly Through Food — Foodborne Diseases Active Surveillance Network, 10 U.S. Sites, 2006–2017
Authors: Ellyn P. Marder, MPH, Patricia M. Griffin, Paul R. Cieslak, John Dunn, Sharon Hurd, Rachel Jervis, Sarah Lathrop, Alison Muse, Patricia Ryan, Kirk Smith, Melissa Tobin-D’Angelo, Duc J. Vugia, Kristin G. Holt, Beverly J. Wolpert, Robert Tauxe, Aimee L. Geissler
Journal: MMWR Morbidity and Mortality Weekly Report (2018)

Despite ongoing food safety measures in the United States, foodborne illness continues to be a substantial health burden. The 10 U.S. sites of the Foodborne Diseases Active Surveillance Network (FoodNet)* monitor cases of laboratory-diagnosed infections caused by nine pathogens transmitted commonly through food. This report summarizes preliminary 2017 data and describes changes in incidence since 2006. In 2017, FoodNet reported 24,484 infections, 5,677 hospitalizations, and 122 deaths. Compared with 2014-2016, the 2017 incidence of infections with Campylobacter, Listeria, non-O157 Shiga toxin-producing Escherichia coli (STEC), Yersinia, Vibrio, and Cyclospora increased. The increased incidences of pathogens for which testing was previously limited might have resulted from the increased use and sensitivity of culture-independent diagnostic tests (CIDTs), which can improve incidence estimates (1). Compared with 2006-2008, the 2017 incidence of infections with Salmonella serotypes Typhimurium and Heidelberg decreased, and the incidence of serotypes Javiana, Infantis, and Thompson increased. New regulatory requirements that include enhanced testing of poultry products for Salmonella† might have contributed to the decreases. The incidence of STEC O157 infections during 2017 also decreased compared with 2006-2008, which parallels reductions in isolations from ground beef.§ The declines in two Salmonella serotypes and STEC O157 infections provide supportive evidence that targeted control measures are effective. The marked increases in infections caused by some Salmonella serotypes provide an opportunity to investigate food and nonfood sources of infection and to design specific interventions.
Clinical Neurology
Authors: Kenneth R. Magee
Journal: JAMA (1965)

The newest of a group of excellent texts on clinical neurology, this book is moderately sized, modestly priced, reasonably thorough, and suitable for both students and physicians. Initial chapters discuss specific aspects of neurologic dysfunction, such as disturbances of somatic function, disorders of the motor system, disorders of speech and language, mental alterations in organic disease, disturbances of the cranial nerves, disorders of the hypothalamus and vegetative nervous system. The remaining portion of the text evaluates specific diseases of both the central and peripheral nervous system, including an extended discussion of diseases of muscle. Illustrations and a detailed index add to the generally attractive format of the book, which is particularly impressive considering its modest price. Although the medical undergraduate and the resident, to whom this book is directed, will find some of the detail unnecessary, this same detail enhances its attractiveness for neurologists and other students of the neurologic
MADRID
Journal: JAMA (1931)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Geriatric Medicine: A Statement from the Federated Council for Internal Medicine
Journal: Annals of Internal Medicine (1981)

The body of knowledge pertinent to the care of the elderly lies largely within internal medicine and its subspecialties. A growing number of elderly persons have great need for medical and social services. The Federated Council for Internal Medicine (FCIM) recommends increased emphasis on geriatric medicine in the medical school curriculum, the medical residency, and continuing medical education; new affiliations of medical schools with geriatric care institutions; and the development of postresidency advanced training in geriatric medicine, aimed primarily at creating teacher-scientists, but also preparing for a consultant role. The FCIM opposes the creation of separate medical school departments and favors inclusion of an administrative mechanism for geriatrics within the department of medicine, preferably linked to the division or section of general internal medicine. The FCIM encourages the American Board of Internal Medicine to continue to explore forms of recognition of advanced training and particular competence in geriatric medicine but opposes the creation of a separate certifying board for geriatrics.
Is underdiagnosis the main pitfall in diagnosing bipolar disorder? No
Authors: M. Zimmerman
Journal: BMJ (2010)

<b>Daniel Smith</b> and <b>Nassir Ghaemi</b> (doi:10.1136/bmj.c854) believe that many people with bipolar disorder remain undiagnosed, but <b>Mark Zimmerman</b> argues that overdiagnosis is the bigger problem
Educating the humanist physician. An ancient ideal reconsidered
Authors: E. D. Pellegrino
Journal: JAMA (1974)

We must understand what man is, for he is the subject matter of the science of medicine for whom it is promulgated. To understand him is to understand the world, for he is similar to the world in his construction. He is the microcosm, the macrocosm in miniature. —The Caraka Samhita<sup>1</sup> IN THE growing litany of criticism to which our profession is increasingly exposed, there is one that in many ways is more painful than all the rest. It is the assertion that physicians are no longer humanists and that medicine is no longer a learned profession. Our technical proficiency is extolled, but in its application we are said to be insensitive to human values. We are, in short, presumed to be wanting as educated men and as responsive human beings. The assertion is painful because there is some truth in it. Moreover, it comes from those who experience
Palliative treatment with gefitinib (G) in advanced and heavy pre-treated non-small cell lung cancer (NSCLC)
Authors: M. Papi, D. Tassinari, E. Pasquini, G. Genestreti, B. Roudnas, F. Fochessati, B. Poggi, M. Fantini, A. Polselli, A. Ravaioli
Journal: Journal of Clinical Oncology (2004)

7308 Background: FDA has recently approved the use of G in the palliative treatment of NSCLC after platinum compounds and docetaxel. We present the data of activity and safety of G in patients with advanced and heavy pre-treated NSCLC. Methods: The records of the patients treated with G were reviewed; all the patients pre-treated with at least one courses of a platinum-containing regimen were considered eligible and enrolled into the trial. All the patients were treated with G 250 mg/die until progression of the disease or intractable toxicity. All the patients were evaluated every 21 days for toxicity and every 2 months for survival. Primary end point was time to progression (TTP); secondary ones were overall survival (OS) and safety. Results: Till today 41 patients were considered eligible and enrolled into the trial; the results are summarised in the table. No significant differences in OS were observed between the patients pre-treated with one line or more than one lines of chemotherapy (respectively 154 days vs 91 days, p=0.9 using the Log-Rank test). Toxicity was mild with no haematological side effects, no grade III-IV not-haematological toxicity, grade I diarrhoea in 8 patients (19.5%), grade II diarrhoea in 1 patient (2.4%), grade I cutaneous toxicity in 10 patients (24.3%), grade II cutaneous toxicity in 1 patient (2.4%) and grade I nausea in 4 patients (9.6%). Conclusions: G seems to represent an interesting options in patients with NSCLC heavily pre-treated with chemotherapy. Our data seems to confirm that G is an active and safe treatment in such a subset of patients, opening a novel dimension in the treatment of pre-treated NSCLC (supported by IOR). No significant financial relationships to disclose.
Deaths
Journal: JAMA (1942)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
FORMATIVE NUTRITION.
Authors: H. W. SCAIFE
Journal: JAMA (1898)

As defined by Webster, nutrition is an "act or process of promoting the growth, or repairing the waste, of animal bodies," from which it appears there are two divisions of nutrition. The first is a "<i>process of promoting the growth</i>." And it is to a consideration of this that this paper is devoted, and hence it is called "Formative Nutrition." "Young men for war and old men for counsel," indicates the physiologic superiority in the face of disease and death which formative nutrition gives to the young. It is then at its best; its capacity for repairing the waste has attained its maximum, and then the frame ceases to be augmented. On an inquiry into the process of forming and building animal tissue, the first point of importance is to find the seat of nutrition, which is easily determined by reducing tissue to its simplest factor; that we find to
Inadvertent transbronchial insertion of narrow-bore feeding tubes into the pleural space
Authors: R. W. Hand
Journal: JAMA (1984)

Four patients had soft, narrow-bore feeding tubes passed transbronchially into the pleural space. Guide wires were used to aid passage and may have contributed to this complication. The errant positioning of the tube was first noted roentgenographically in each case. Alternate methods of inserting such tubes in patients with altered airway and swallowing reflexes may be needed. Radiographic confirmation of the tube's position is essential before starting tube feedings. (<i>JAMA</i>1984;251:2396-2397)
Physician service opportunities abroad
Authors: M. F. Goldsmith
Journal: JAMA (1993)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Preluxation of Hip in the Newborn: Diagnosis, Treatment, and Course
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
NIAID Study Identifies Factors That Affect Renal Transplantation Outcome
Journal: JAMA (1981)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
PRESIDENT'S ADDRESS
Authors: JAS. E.  PAULLIN
Journal: Annals of Internal Medicine (1944)

Article1 May 1944PRESIDENT'S ADDRESSJAS. E. PAULLIN, F.A.C.P.JAS. E. PAULLIN, F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-20-5-733 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptWhen the Board of Regents deferred the annual meeting of The American College of Physicians, which was to have been held at Philadelphia in 1943, the Officers, Regents and Governors were requested to hold over until such time as it would be possible to have either a regular or a business meeting. This gathering is a combination meeting which permits a short scientific session devoted entirely to problems of military medicine and furnishes an opportunity to those of us who have been "frozen" to become "thawed out." You have elected new officers and are now ready to consider plans and... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Atlanta, Georgia*Delivered at the meeting of the American College of Physicians, Chicago, Illinois, April 1, 1944. Nextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 May 1944Volume 20, Issue 5Page: 733-737KeywordsMilitary medicine ePublished: 1 December 2008 Issue Published: 1 May 1944 Copyright & PermissionsCopyright, 1944, by The American College of PhysiciansPDF downloadLoading ...
This Week in <EMPH TYPE="ITAL">JAMA</EMPH>
Journal: JAMA (2003)

A Piece of My Mind"Growing up, I had seen my father sick enough to stay in bed only once and thus was convinced he was invulnerable."From "Reflections While Listening to the Glazunov Saxophone Concerto." SEE PAGE 1683 Medical News & PerspectivesDriven by concerns that the severe acute respiratory syndrome (SARS) will make a return appearance on the world's stage, researchers are testing existing drugs and new agents as possible anti-SARS drugs.
Prognostic value of tumor deposits for disease free survival in patients with stage III colon cancer: A post hoc analysis of IDEA France phase III trial (PRODIGE-GERCOR).
Authors: Jean Francois Delattre, Romain Cohen, Julie Henriques, Antoine Falcoz, Jean-François Emile, Serge Fratte, Benoist Chibaudel, Jérôme Dauba, Olivier Jean Marie Dupuis, Yves Bécouarn, Frédéric Bibeau, Julien Taieb, Thierry Andre, Dewi Vernerey, Magali Svrcek
Journal: Journal of Clinical Oncology (2019)

3519 Background: Tumor deposits (TDs) are isolated tumor foci in the pericolic, perirectal or mesocolic fat without residual lymph node (LN) tissue. TDs seem to impact the prognosis of stage III colon cancer (CC) patients (pts) but are only considered in TNM staging in the absence of LN metastases (LNM). We aimed at evaluating the prognosis value for disease free survival (DFS)of TDs in International Duration Evaluation of Adjuvant Chemotherapy (IDEA) France phase III study (NCT00958737) that compared 3 versus 6 months of adjuvant FOLFOX or CAPOX for stage III CC pts. Methods: All pathological reports of pts included in IDEA France trial were retrospectively analyzed. DFS according to the presence or absence of TDs was evaluated using Kaplan-Meier estimator. Multivariable Cox model analysis was performed to evaluate the association between TDs and DFS. This analysis did not included immunohistochemical biomarkers. Results: Among the 2022 pts included in IDEA France study, 1942 (96%) were analyzed. 80 pts were excluded: no pathological report (n = 68), pts without treatment (n = 12). TDs were found in 184 pts (9.47%), of whom 74 with N1a/b (40%), 55 with N1c (30%) and 55 with N2 LN stage (30%). All characteristics were similar according to the presence of TDs, except for tumor/node (TN) stage (T4 and/or N2 are more frequent in pts with TDs; p = .0046). The 3-year DFS rates were 65.59% [95% confidence interval (95%CI) 58.04-72.12] and 74.71% [95%CI 72.57-76.71] for pts with and without TDs, respectively (p = 0.0079). In multivariable analysis, TDs were associated with higher risk of recurrence or death (hazard ratio (HR) = 1.36, 95%CI 1.05-1.75, p = .0201), as well as T4 and/or N2 (HR = 2.21, 95%CI 1.03-1.59, p &lt; .001), 3 months of adjuvant treatment (HR = 1.29, 95%CI 1.09-1.52, p = .0029), obstruction (HR = 1.28, 95%CI 1.03-1.59, p = .0233) and male (HR = 1.24, 95%CI 1.04-1.46, p = .0151). Adding TDs count to the LNM count, 35 out of 1454 N1a/b/c CC pts (2.4%) were reclassified as N2 and experienced worse 3 years DFS than confirmed N1 CC pts (p = .0151). Conclusions: TD is an independent and valuable prognostic factor for DFSin stage III CC pts and should be considered whatever the LNM status.
Chemotherapy of Human Cancer with Sulfhydryl Inhibitors
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE FOOD AND DRUGS ACT REVISION
Journal: JAMA (1935)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal