tbuckley/cabot-search huggingface dataset:
Leads from the MMWR. Sex- and age-specific prevalence of heavier drinking in selected states in 1985--the Behavioral Risk Factor Surveys
Journal: JAMA (1987)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Phase I Trial of Belinostat and Bortezomib in Patients with Relapsed or Refractory Acute Leukemia, Myelodysplastic Syndrome, or Chronic Myelogenous Leukemia in Blast Crisis
Authors: Beata Holkova, Mary Beth Tombes, Ellen Shrader, Sheryl S. Cooke, Wen Wan, Heidi Sankala, Maciej Kmieciak, John D. Roberts, Guillermo Garcia-Manero, Steven Grant
Journal: Blood (2011)
Rounds: Neonatology
Authors: Carol Guess
Journal: JAMA (1991)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Pathology of the Eye.
Journal: JAMA (1907)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Erratum: Expression of the CTLA-4 ligand CD86 on plasmacytoid dendritic cells (pDC) predicts risk of disease recurrence after treatment discontinuation in CML
Authors: C Schütz, S Inselmann, S Saussele, C T Dietz, M C Müller, E Eigendorff, C A Brendel, S K Metzelder, T H Brümmendorf, C Waller, J Dengler, M E Goebeler, R Herbst, G Freunek, S Hanzel, T Illmer, Y Wang, T Lange, F Finkernagel, R Hehlmann, M Huber, A Neubauer, A Hochhaus, J Guilhot, F X Mahon, M Pfirrmann, A Burchert
Journal: Leukemia (2018)
Refraction of the Eye, Including a Complete Treatise on Ophthalmology. A Clinical Text-Book for Students and Practitioners.
Journal: JAMA (1900)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Factors Related to Pleural Effusions After Fontan Procedure in the Era of Fenestration
Authors: Raymond T. Fedderly, Beth N. Whitstone, Stephanie J. Frisbee, James S. Tweddell, S. Bert Litwin
Journal: Circulation (2001)

Background Significant pleural effusions after the Fontan operation prolong hospital stay, may increase the risk of infection, and may necessitate a pleurodesis procedure. Methods and Results From February 1991 to April 2000, 98 consecutive patients under the age of 18 years underwent the fenestrated Fontan procedure at Children’s Hospital of Wisconsin. Ninety-four patients who survived at least 30 days after surgery were retrospectively evaluated for the following factors: age, ventricular morphology (right single ventricle, left single ventricle [RV/LV]), fenestration open (FO) or closed (FC) at end of operation, intracardiac Fontan (IF) or extracardiac Fontan (EF), days with chest tube output per day &gt;5, 10, and/or 20 mL · kg −1 · d −1 (CTO5, CTO10, and CTO20, respectively), need for pleurodesis, length of hospital stay (LOS), operation during winter respiratory viral season of November through March (ReVS+, ReVS−), and pre-Fontan mean pulmonary artery pressure (PAP) and pulmonary vascular resistance (PVR). In univariate analysis, the ReVS+ patients had prolonged LOS, greater chest tube output, and more pleurodesis ( P &lt;0.05), and PAP was related to CTO5 and CTO10 but not to CTO20 or LOS. No significant differences were found in LOS, CTO5, CTO10, CTO20, and need for pleurodesis between patients in RV/LV, FO/FC, IF/EF, or PVR groups. Patients &lt;4 years of age had more instances of CTO20 ( P &lt;0.05). When we used ordinary least squares regression analysis with age, FO or FC, RV or LV, PAP, and ReVS+ or ReVS− to predict each of CTO5, CTO10, CTO20, and LOS, only ReVS+ or ReVS− and age were statistically significant in all models. Conclusions Use of the Fontan procedure during the respiratory viral season appeared to be related to significant, prolonged pleural effusions and longer hospitalizations.
Prevention of Bacterial Endocarditis: American Heart Association Recommendations
Authors: Jay Y. Park
Journal: JAMA (1997)

<h3>To the Editor.</h3> —For the most part, the updated recommendations by the American Heart Association (AHA)<sup>1</sup>for the prevention of bacterial endocarditis are thoughtful and comprehensive. Unlike the 1990 recommendations,<sup>2</sup>the subject of antibiotic prophylaxis for cutaneous surgery is at least briefly mentioned although not specifically discussed. In the current statement, endocarditis prophylaxis is not recommended for "incision or biopsy of surgically scrubbed skin."<sup>1</sup>Unfortunately, the meaning of "surgically scrubbed skin" is not clarified. Does this refer to "sterile" prepared skin as in the operating room setting or to "clean" prepared skin as in the outpatient office setting? Dermatologic surgery, which is performed predominantly in a "clean" outpatient office setting, is becoming a more frequent phenomenon because of the increasing number of dermatologists performing these procedures. Furthermore, with third-party payers giving increasing emphasis to outpatient surgery, plastic surgeons, otolaryngologists, and other surgical specialists are performing a greater
Vitamin E in Humans: Demand and Delivery
Authors: M. G. Traber
Journal: Annual Review of Nutrition (1996)

How much vitamin E is enough? An established use of supplemental vitamin E in humans is in the prevention and therapy of deficiency symptoms. The cause of vitamin E deficiency, characterized by peripheral neuropathy and ataxia, is usually malabsorption—a result of fat malabsorption or genetic abnormalities in lipoprotein metabolism. Genetic abnormalities in the hepatic α-tocopherol transfer protein also cause vitamin E deficiency—defects in this protein cause an impairment in plasma vitamin E transport. Impaired delivery of vitamin E to tissues, thereby, results in deficiency symptoms. Also discussed is the use of supplemental vitamin E in chronic diseases such as ischemic heart disease, atherosclerosis, diabetes, cataracts, Parkinson's disease, Alzheimer's disease, and impared immune function, as well as in subjects receiving total parenterol nutrition. In healthy individuals, a daily intake of about 15-30 mg of α-tocopherol is recommended to obtain "optimal plasma alpha-tocopherol concentrations" (30 μM or greater).
Tetanus
Authors: S. Wessler
Journal: JAMA (1969)

Dr. John W. Sullivan, Junior Assistant Resident in Medicine, Jewish Hospital of St. Louis, and assistant in Medicine, Washington University School of Medicine: A 67-year-old white woman was admitted to the Jewish Hospital for the first time on July 30, 1968, because of shoulder and neck pain and inability to open her mouth. Eleven days before admission, a nail, thrown by a motorized lawnmower, had pierced her right calf. The nail was removed, the laceration sutured, and tetanus toxoid administered. On subsequent questioning the patient did not recall previous tetanus immunization. During the ensuing several days the patient noted a foul odor of the wound when she changed the dressing. Eight days after the injury, she first noted tightened facial muscles and a persistent pain between her scapulae. Shortly thereafter, she was unable to swallow her oral secretions. Her physician reopened the laceration, administered penicillin G potassium parenterally, and transferred
Marriages
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
DISCUSSION: The athlete's knee and ankle
Journal: British Journal of Sports Medicine (1980)

RENSTROM started the discussion on instability of the knee, the mechanism of stabilising ligaments and bones, and the necessity of ligament strength rather than muscle contraction to offset the stresses imposed by sport.Muscles are active stabilisers and protective to a certain extent and the ligaments are passive and thereby the main stabilisers.There are differences between active stability, depending upon quadriceps and hamstrings contraction, and passive stability depending upon ligaments.Johnson (1978) showed that reflex activation time was shorter for ligament than for muscle, the latter assisting in stabilisation after ligaments have borne the initial strain.J. P. S. ENGLAND said that provided the cruciate and capsular ligaments are intact, however, the knee may appear stable functionally, despite collateral ligament damage.J. G. P. WILLIAMS amplified this idea in assuming that the muscles were in a flaccid state when Johnson performed his experiments, but as muscle is a dynamic structure in the alert athlete it will be in tension before stress is applied.The trained athlete develops movement patterns that should enable muscles to react in time, provided training is adequate and undue fatique avoided.A sprinter may be able to run 100 M with a complete tear of the medial collateral ligaments, but be unable to make a sudden turn.For these rotational stresses a dynamic stabilisation such as a pes anserinus transplant, or a static one by ligament repair is necessary.A Principal feature of instability of any joint is proprioceptive feedback, and failure of this interferes with the protective action of muscles, and leads to injury.J. P. S. ENGLAND.A knee can be functionally stable even with a complete rupture of the anterior cruciate ligament.P. RENSTROM mentioned Ljungqvist's (1979) series of about 80 athletes including many jumpers with partial rupture of the infrapatellar ligament often located to the posterior aspect of the ligament.J. G. P. WILLIAMS noted that the histology of these lesions was identical with his own series of achilles tendon injuries.T. DURKIN raised the possibility of cruciate repair or replacement with carbon fibre filaments, now being pioneered by Jenkins in Cardiff.J. P. S. ENGLAND stated that this work was still in early stages, and doubted whether the technique had been perfected sufficiently for the stresses imposed by sport.J. G. P. WILLIAMS discussed various techniques of cruciate ligament repair, including Erikson's operation for anterior cruciate tears, a modification of Lamb's operation.J. P. S. ENGLAND commented that a problem in Britain, was the difficulty in getting suitable patients early enough, compared with the two or three weeks reported by Renstrom..
Mediation Analysis
Authors: Hopin Lee, Robert D. Herbert, James H. McAuley
Journal: JAMA (2019)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Osteoporosis
Authors: David A. Ontjes
Journal: JAMA (2008)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Long-term survival among men with conservatively treated localized prostate cancer
Authors: P. C. Albertsen
Journal: JAMA (1995)

<h3>Objective.</h3> —To determine age-specific, all-cause mortality, disease-specific mortality, and life expectancy for men aged 65 to 75 years who are treated only with immediate or delayed hormonal therapy for newly diagnosed, clinically localized prostate cancer. <h3>Design.</h3> —A population-based, retrospective cohort study. <h3>Setting.</h3> —Patient records were abstracted from 37 acute care hospitals and two Veterans Affairs medical centers in Connecticut. Original pathology slides were sent to a referee pathologist who was blinded to case outcomes. <h3>Subjects.</h3> —All men identified by the Connecticut Tumor Registry with clinically localized prostate cancer diagnosed in 1971 to 1976 who were aged 65 to 75 years at the time of diagnosis and were untreated or treated with immediate or delayed hormonal therapy. <h3>Main Outcome Measures.</h3> —Parametric proportional hazards models incorporating tumor histologic findings, comorbidity, and age at the time of diagnosis to compare cohort survival with that of men in the general population. <h3>Results.</h3> —After a mean follow-up of 15.5 years, the age-adjusted survival for men with Gleason score 2 to 4 tumors was not significantly different from that of the general population. Maximum estimated lost life expectancy for men with Gleason score 5 to 7 tumors was 4 to 5 years and for men with Gleason score 8 to 10 tumors was 6 to 8 years. Tumor histologic findings and patient comorbidities were powerful independent predictors of survival. <h3>Conclusions.</h3> —Compared with the general population, men aged 65 to 75 years with conservatively treated low-grade prostate cancer incur no loss of life expectancy. Men with higher-grade tumors (Gleason scores 5 to 10) experience a progressively increasing loss of life expectancy. Case series reports of survival/ mortality experienced by men with clinically localized prostate cancer that fail to control for age, tumor histologic features, and comorbidities risk significant bias. (<i>JAMA</i>. 1995;274:626-631)
Specificity and sensitivity of gp210 autoantibodies detected using an enzyme-linked immunosorbent assay and a synthetic polypeptide in the diagnosis of primary biliary cirrhosis
Authors: O Bandin
Journal: Hepatology (1996)

Between 10% and 42% of patients with primary biliary cirrhosis (PBC) have been reported to have autoantibodies directed against a restricted epitope of gp210, a glycoprotein of the nuclear pore membrane. The prevalence and specificity of these antibodies was studied in a French series of 285 patients with PBC and 497 control individuals affected with other liver or autoimmune diseases. Sera were analyzed by an enzyme-linked immunosorbent assay (ELISA) that used a synthetic polypeptide containing the predominant autoepitope of gp210, in parallel to immunoblotting of gp210 protein and immunofluorescence microscopy. Autoantibodies to the gp210 epitope detected by ELISA were 25.5% sensitive and 99.5% specific for the diagnosis of PBC. These results were in agreement with a 99.4% specificity with immunoblotting analysis and a 96.6% specificity with immunofluorescence. In a subset of PBC patients without detectable antimitochondrial autoantibodies (AMA), gp210 autoantibodies were found in 7 of 15 patients (47%). Therefore, gp210 autoantibodies are highly specific for PBC and may be of particular utility in assessing patients without AMA or with other atypical presentations.
Gastrocolic fistula as a complication of carcinoma of the lung
Authors: E. R. Thal
Journal: JAMA (1976)

HALLER described the first gastrocolic fistula caused by a malignant neoplasm in 1775. Since then, less than 250 malignant gastrocolic fistulas have been reported.<sup>1</sup>Whereas these fistulas have all been caused by primary intra-abdominal tumors, the following case report is, apparently, the first description of such a condition arising from a primary neoplasm outside the peritoneal cavity. <h3>Report of a Case</h3> A 53-year-old man was admitted to the Dallas Veterans Administration Hospital in the spring of 1974 for evaluation of a cavitary mass in the left upper lobe. After a thorough diagnostic work-up, a left upper lobectomy was performed for a poorly differentiated bronchogenic carcinoma (Fig 1) with metastasis to one periaortic node. Postoperative irradiation totaling 5,000 rads was administered to the hilar area. The patient did well for seven months and then began having intermittent epigastric pain, anorexia, weakness, and a weight loss of 7 kg. After two
Proffered papers
Authors: P O'dwyer, R Perini, A Demichele, D Vaughn, W Sun, B Giantonio, U Teitelbaum, S Randolph, J Christensen, D Pryma, C Divgi, Susan Bates, Francine Foss, Richard Piekarz, Steven Horwitz, Barbara Pro, Miles Prince, Lubomir Sokol, Matthew Greenwood, Dolores Caballero, Peter Borchmann, Franck Morschhauser, Martin Wilhelm, Lauren Pinter-Brown, Swaminathan Padmanabhan, Andrei Shustov, John Wright, Mark Kirschbaum, Jasmine Zain, Steven Allen, Elaine Jaffe, Jean Nichols, Julie Wolfson, John Balser, Bertrand Coiffier
Journal: Annals of Oncology (2011)