tbuckley/cabot-search huggingface dataset:
Adolescents and chronic illness
Authors: D. M. Siegel
Journal: JAMA (1987)

An epidemiologic background of chronic illness in children in the United States is presented, including prevalence data for 21 major chronic conditions. Normal adolescent development is reviewed, and the impact of chronic disease on this development is discussed. Finally, access to care for these patients and participation by primary providers are examined. (<i>JAMA</i>1987;257:3396-3399)
Weapons for protection in home invasion crimes
Authors: J. J. Fotis
Journal: JAMA (1996)

<h3>To the Editor.</h3> —As a former police officer and executive director of an organization representing law enforcement personnel and crime victims, I was surprised that Dr Kellermann and his colleagues<sup>1</sup>used police reports to study the problem of home invasion—burglary of an occupied residence. Their methods suggest that the results of this study cannot contribute any new data to our knowledge of the nature of such crimes or to effective means of protecting one's self or family from them. First, the greatest utility of police reports is in helping police departments allocate limited resources to deal with often unlimited need. These reports provide useful information in investigating crimes, but are not designed and are not intended to provide statistically sound information on the nature of crimes, such as break-ins. Only coincidentally are some data on the reports, such as method of entry, of possible narrow help in surveys such
Breast cancer induced by radiation. Relation to mammography and treatment of acne
Authors: N. Simon
Journal: JAMA (1977)

This communication reports cases of 16 women in whom cancer of the breast developed after radiation therapy for acne or hirsutism, suggesting another group at higher risk than is generally expected for cancer of the breast. It is prudent to regard the carcinogenic effect of radiation on the breast as proportional to dose without a threshold. Mammography in young women should be ordered only selectively, not for screening. (<i>JAMA</i>237:789-790, 1977)
Editorial Board
Authors: Zuhair Ballas, Iowa City, Andrea Apter, Leonard Philadelphia, St Bacharier, Claus Louis, Joshua Boyce, Robert Bush, Javier Chinen, Raif Geha, Kyoto Japan, Carole Ober, David Peden, Chapel Hill, Harald Renz, Marburg Germany, Marc Rothenberg, Cincinnati Ohio, Hirohisa Saito, Tokyo Japan, Stephan Weidinger, Robert Wood, Paul Bryce, Mariana Castells, Mitchell Grayson, Columbus Ohio, Bruce Mazer, Ariel Munitz, Kari Nadeau, Bruce Bender, Pascal Chanez, Morton Cowan, San Francisco, Elizabeth Matsui, Katrina Allen, Peter Arkwright, Arthur Gelb, Los Angeles
Journal: Journal of Allergy and Clinical Immunology (2018)
Third International Conference on Adjuvant Therapy of Cancer
Journal: JNCI Journal of the National Cancer Institute (1980)

Journal Article Third International Conference on Adjuvant Therapy of Cancer Get access JNCI: Journal of the National Cancer Institute, Volume 65, Issue 2, August 1980, Page 491, https://doi.org/10.1093/jnci/65.2.491 Published: 01 August 1980
Passive Smoking: Beliefs, Attitudes, and Exposures—United States, 1986
Journal: JAMA (1988)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A mechanical 'hypothalamus' for ovulation induction therapy
Authors: V. M. Sopelak
Journal: JAMA (1984)

In the normal menstrual cycle, the functional integrity of the hypothalamic-pituitary-ovarian axis requires the pulsatile secretion of gonadotropin-releasing hormone (GnRH) from the hypothalamus. This hypothalamic hormone, also known as luteinizing hormone-releasing hormone, stimulates pituitary gonadotropin (luteinizing hormone and follicle-stimulating hormone) secretion, promoting ovarian follicular maturation, ovulation, and corpus luteum function.<sup>1,2</sup>When the hypothalamus fails to provide an appropriate GnRH stimulation of the pituitary gland, anovulatory infertility often occurs. Recent advances in neuroendocrine physiology demonstrate that pulsatile GnRH replacement therapy can restore ovulation and fertility. Infertility specialists are learning how to provide pulsatile GnRH therapy for the treatment of hypothalamic hypogonadism in both men and women.<sup>3-5</sup>Recent evidence also suggests that higher-dose pulsatile GnRH treatment may be used to achieve multiple follicular growth for in vitro fertilization therapy, when the collection of several mature oocytes is desired.<sup>6</sup>
Children's Inn Opens at NIH
Journal: JNCI Journal of the National Cancer Institute (1990)

Journal Article Children's Inn Opens at NIH Get access JNCI: Journal of the National Cancer Institute, Volume 82, Issue 14, 18 July 1990, Pages 1183–1185, https://doi.org/10.1093/jnci/82.14.1183-a Published: 18 July 1990
OPINION EVIDENCE BASED ON CONDITION OF BROKEN BONES.
Journal: JAMA (1893)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Alcohol Availability and Alcoholism
Journal: JAMA (1995)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Physician-Assisted Suicide
Authors: James T. D'Olimpio
Journal: JAMA (1995)

<h3>To the Editor.</h3> —I read, with dismay, the article by Ms Alpers and Dr Lo<sup>1</sup>that characterized Oregon's physician-assisted suicide law as a "bold experiment." Chillingly, it ratifies this act as a fait accompli that physicians need to accept by cooperating in compiling relevant empirical data on such a practice. As a clinician trained in medical oncology and as a medical director of a hospice program in New York, I believe physicians should take an active stance against this practice. It should not be accepted as a reality, as the authors do so dispassionately. Such detached language by these authors completely misses the point as to why this law is unworkable and ultimately impossible to regard with any degree of professional respect, integrity, and relevance. Improving care of terminally ill patients requires a degree of medical expertise and compassion and a clinical knowledge base most physicians simply do not
Selenium and Vitamin E Supplementation for Cancer Prevention—Reply
Authors: Scott M. Lippman
Journal: JAMA (2009)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Gastric Secretion and Alimentary Lipemia in Ischemic Heart Disease
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Chlorpheniramine-dependent thrombocytopenia
Authors: E. V. Eisner
Journal: JAMA (1975)

SEVERE thrombocytopenia, as a consequence of an immune reaction, is a rare complication of therapy with a wide variety of drugs.<sup>1</sup>With respect to the antihistamines, antibody-mediated thrombocytopenia has been demonstrated in only a single case in which antazoline hydrochloride was implicated.<sup>2</sup>We report a case of chlorpheniramine-induced thrombocytopenic purpura in which serologic study established the presence of a drug-dependent IgG antiplatelet antibody. The patient's serum displayed antiplatelet activity in the presence of the closely related compound, brompheniramine maleate, but did not react with other antihistamines. <h3>Report of a Case</h3> A 53-year-old man was hospitalized on Sept 20, 1973, with generalized petechiae, hematuria, and melena. In the spring and summer of 1951 he had been hospitalized three times for severe acute thrombocytopenia. Each episode had followed an upper respiratory tract infection, and complete recovery had occurred spontaneously within two weeks. In August 1951 he underwent splenectomy, despite a
Splenic Hemangioma
Authors: JOE C. LEONARD, PATRICK D. BARNES, JOSEPH D. KERN
Journal: Clinical Nuclear Medicine (1981)

*From the Department of Nuclear Medicine, Oklahoma Children's Memorial Hospital and Oklahoma University Health Sciences Center, Oklahoma City, Oklahoma †From the Department of Radiology, Oklahoma Children's Memorial Hospital and Oklahoma University Health Sciences Center, Oklahoma City, Oklahoma ‡From the Department of Pathology, Oklahoma Children's Memorial Hospital and Oklahoma University Health Sciences Center, Oklahoma City, Oklahoma
ANOTHER VICTIM TO PLAGUE INVESTIGATION.
Journal: JAMA (1903)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Home Parenteral Nutrition
Authors: Sharon Grundfest
Journal: JAMA (1980)

HOME parenteral nutrition (HPN) has revolutionized the treatment of formally fatal intestinal problems in much the same way that renal dialysis has affected the outlook for patients with chronic renal failure. Until recently, patients with severe malabsorption syndromes or massive small-bowel resections occasioned by vascular accidents, inflammatory bowel disease, or radiation enteritis were doomed to repeated hospitalizations or even death from dehydration, electrolyte abnormalities, and malnutrition. Now such patients may be able to resume a normal nutritional status and a nearly normal life-style. The idea of providing enough nutritional support by the intravenous (IV) route to achieve positive nitrogen balance should probably be credited to Elman,<sup>1</sup>who in 1948 reported decreased postoperative morbidity in patients given dextrose and protein hydrolysates via peripheral veins. In 1952, Aubaniac<sup>2</sup>described the technique of percutaneous subclavian venipuncture; however, it remained for Dudrick and colleagues<sup>3</sup>to prove that hypertonic solutions of dextrose,
BELGIUM
Journal: JAMA (1928)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Epirubicin-Based Chemotherapy in Metastatic Breast Cancer Patients: Role of Dose-Intensity and Duration of Treatment
Journal: Journal of Clinical Oncology (2000)

PURPOSE: To determine whether the duration and the dose of epirubicin modify the long-term outcome of patients with metastatic breast cancer (MBC). PATIENTS AND METHODS: Four hundred seventeen anthracycline-naive MBC patients were randomized to receive one of the following regimens: arm A: 11 cycles of fluorouracil 500 mg/m 2 , epirubicin 75 mg/m 2 , and cyclophosphamide 500 mg/m 2 (FEC 75) every 21 days; arm B: four cycles of FEC 100 (same regimen but with epirubicin 100 mg/m 2 ) then eight cycles of FEC 50 (epirubicin 50 mg/m 2 ); and arm C: four cycles of FEC 100 then restart the same regimen at disease progression in case of prior response or stabilization. RESULTS: Hematologic toxicity was similar. Nausea/vomiting and stomatitis were significantly less frequent in arm A as was left ventricular ejection fraction decrease in arm C (A = six patients, B = five patients, and C = one patient). Six patients died of infections (A = four patients and C = two patients). After four cycles, the objective response rate (ORR) was better with FEC 100 than with FEC 75 (49.2% v 40%, respectively; P = .07). The ORR was better with the longer regimens (arm A, 56.9%; B, 64%; and C, 47.6%; P = .06) and was 41% after second-line FEC 100. After a median follow-up of 41 months, the response duration and time to progression (TTP) were significantly better with arm B, the longer regimen (P = .012 and P &lt; 10 −3 , respectively). The median survival times for arms A, B, and C were similar (17.9, 18.9, and 16.3 months, respectively; P = .49). CONCLUSION: In MBC, longer epirubicin-based regimens are better in terms of response duration and TTP. FEC 100 regimens improve the ORR. However, four initial cycles of FEC 100 and identical retreatment at disease progression yielded equivalent overall survival to longer regimens.
Perforating Injuries of Rectum and Sigmoid Colon
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Phencyclidine Poisoning
Authors: Theodore G. Tong
Journal: JAMA (1975)

Phencyclidine hydrochloride abuse has become increasingly common and should be considered in patients with unexplained acute psychosis, dystonic reactions, status epilepticus, or coma. Two phencyclidine-intoxicated patients had bizarre combinations or disorientation, hallucination, agitation, and dyskinetic motor activity. Supportive care and reduction of sensory stimulation are the basis for management of the symptoms.
Abstract 1085: Neuropilin-1 deficient macrophages as a treatment strategy for glioblastoma
Authors: Michael D. Caponegro, Stella E. Tsirka
Journal: Cancer Research (2019)

Abstract Post-diagnosis survival of grade IV glioblastoma (GB) is a dismal 14 months in patients receiving standard of care therapy. With the development of immunotherapeutic strategies targeting non-cancerous, stromal cells of the tumor microenvironment (TME), new avenues are being pursued in clinical trials and pre-clinical animal models of advanced GB. Glioma-associated microglia/macrophages (GAMs) of the TME promote chemoattraction, immune suppression, neoangiogenesis, and tumor cell survival, which parallels tumor-infiltrating macrophage behavior of other solid malignancies. GAMs are now recognized as a potentially practical immunotherapeutic target in GB. Previously in our lab, we have shown that GAM-specific deletion of the cell surface co-receptor Neuropilin-1 (NRP1) drastically reduces pro-tumorigenic behavior of infiltrating microglia and/or macrophages in murine glioma by reducing immunosuppressive tendencies and neoangiogenesis. As an extension to our genetically-ablated mouse model, we present here a platform by which these NRP1-deficient monocytic cells can be harvested ex vivo and locally delivered into the TME of the bulk glioma lesion, to exert anti-tumorigenic effects. To our knowledge, this is the first attempt to deliver cells of monocytic origin intratumorally as a therapeutic option. Citation Format: Michael D. Caponegro, Stella E. Tsirka. Neuropilin-1 deficient macrophages as a treatment strategy for glioblastoma [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 1085.
Asylum
Authors: Peter Byrne
Journal: BMJ (2005)

Directed by David Mackenzie UK release date: 9 September www.paramountclassics.com/asylum/ Rating: ![Graphic][1]</img>![Graphic][2]</img>![Graphic][3]</img>![Graphic][4]</img> T here are many reasons to dislike Asylum . It is dark, with a plot driven by a cruel “what's the worst that can happen” logic, and not one character is better off by the end of the film. From a mental health perspective, it has every negative cliché: treatment is coercive and useless, people who have been ill can only pretend to get better, and mental illness makes violence to self and others inevitable. While it makes no claims to docudrama, its representations of 1950s forensic psychiatry acquire their own reality, and spectators will have their worst negative stereotypes confirmed. Its grim plot is also familiar: the bored wife of one of the … [1]: /embed/inline-graphic-1.gif [2]: /embed/inline-graphic-2.gif [3]: /embed/inline-graphic-3.gif [4]: /embed/inline-graphic-4.gif