tbuckley/cabot-search huggingface dataset:
Medical Economics
Journal: JAMA (1925)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
J Pharmacol &amp;amp; Exper Therapeutics, Baltimore
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Urine in technicolor
Authors: L. B. Berman
Journal: JAMA (1974)

THE familiar color of urine may dramatically depart from yellow to assume various shades of white, orange, green, red, brown, and black. This urinary rainbow contains a treasure of clinical clues to the physician, who reads them correctly. For example,<i>milky white</i>urine may be the result of pus, phosphate crystals, or occasionally chyle. The first two can be separated by centrifugation and then identified microscopically. It may not even be necessary to do this if the urine pH is below 7.0, for phosphates will not precipitate in acid urine. Chyle is also associated with an alkaline urine, and is identified by its extractability with fat solvents.<i>Green</i>urine represents a mixture of blue and yellow. Therefore, a<i>Pseudomonas</i>infection (blue pus) or ingestion of a methylene blue dye will combine with the normal yellow urochrome and emerge as green. The spectrum of<i>red, brown</i>, and<i>black</i>should be separated
Manuscripts Approved for JNCI, June 1 to July 1, 1966
Journal: JNCI Journal of the National Cancer Institute (1966)

Manuscripts Approved for JNCI, June 1 to July 1, 1966 Get access JNCI: Journal of the National Cancer Institute, Volume 37, Issue 2, August 1966, Page 258, https://doi.org/10.1093/jnci/37.2.258-b Published: 01 August 1966
A clinical validation study of RASKET-B: A multiple detection kit for RAS and BRAF gene mutations in colorectal cancer
Authors: W. Okamoto, K. Muro, H. Taniguchi, K. Akagi, H. Hara, T. Nishina, T. Kajiwara, T. Denda, S. Hironaka, T. Kudo, T. Satoh, T. Yoshino
Journal: Annals of Oncology (2017)
Letter: More on catfish stings
Authors: B. M. Patten
Journal: JAMA (1975)

On receiving a routine inquiry as to whether he wished to order reprints of his publication, Prof R. G. Huntsman of London, England, replied as follows: You are plainly unaware that the National Health Service is bankrupt! In these circumstances, we will clearly have to do without reprints. We received far more mail on Dr. Charles H. Scoggin's article, "Catfish Stings" (231:176, 1975), than we could publish. One letter, by Dr. Bernard M. Patten, appears in this issue (see p 248). John M. Brenner, MD, of Costa Mesa, Calif, and Ray V. McIntyre, MD, of Kingfisher, Okla, join Dr. Patten in recommending immersion of the wounded extremity in hot water. Dr. Brenner uses water as hot as tolerable, up to 51 C (125 F), provided there is no contraindication such as peripheral vascular disease. Dr. McIntyre reports success with temperatures of 38 to 41 C (100 to 105 F). L.
Liver - general
Authors: P Queneau, F Mion, M Rousseau, J Brazier', P Paliard, Y Minaire
Journal: Gut (1993)

Objective:We report on 2000 "ultrasonically-guided" percutaneous liver biopsies in outpatients. 1200biopsies were performed by Menghini, 800 by Trucut needle.The risk of the procedure was compared between the two groups and the ultrasound investigation was evaluated for its effectiveness. Methods:The puncture site was marked based on sonographic findings, excluding cysts, metastases and haemangiomas.The gallbladder was localised and the maximal depth of puncture recorded.Biopsy was performed in standard technique under local anaesthesia.After biopsy, pain, blood pressure and clinical status were recorded for three hours.Ultrasound investigations were perfor- med (Hitachi EUB 340, Diasonics-Spectra, Diasonics-Prisma, 3,5 and 5 Mlegahertz) after two and three hours. Results:Wi thin ten years, more than 2000 patients were biopsied.There were no serious complications requiring operations, trans- fusions, or volume replacement.Slaght complications were treated symptomatically.Seven patients were admitted for 24 hours because ultrasonography had revealed traces of intra- abdominal fluid.Haematoma after puncture was a rare event (24 cases).There were no differences in the complication xrate between the Menghini and the Trucut group. Conclusions:Sonographically guided percutaneous liver biopsy can be judged safe even in outpatients.Every hepatology unit should be equipped with an ultrasound scanner to minimize the risk of this procedure.Only typical puncture sites marked under sono- graphic guidance should be used.Since tissue yield of the Trucut needle is better and risk is not increased this needle should be preferred.
CORRECTION
Journal: JAMA (1978)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
IL-1 mediates TNF-induced osteoclastogenesis
Authors: Shi Wei, Hideki Kitaura, Ping Zhou, F. Patrick Ross, Steven L. Teitelbaum
Journal: Journal of Clinical Investigation (2005)

TNF-induced receptor activator NF-κB ligand (RANKL) synthesis by bone marrow stromal cells is a fundamental component of inflammatory osteolysis. We found that this process was abolished by IL-1 receptor antagonist (IL-1Ra) or in stromal cells derived from type I IL-1 receptor–deficient (IL-1RI–deficient) mice. Reflecting sequential signaling of the cytokines TNF and IL-1, TNF induces stromal cell expression of IL-1 and IL-1RI. These data suggest that TNF regulates RANKL expression via IL-1, and, therefore, IL-1 plays a role in TNF-induced periarticular osteolysis. Consistent with this posture, TNF-stimulated osteoclastogenesis in cultures consisting of WT marrow macrophages and stromal cells exposed to IL-1Ra or in cocultures established with IL-1RI–deficient stromal cells was reduced approximately 50%. The same magnitude of osteoclast inhibition occurred in IL-1RI–deficient mice following TNF administration in vivo. Like TNF, IL-1 directly targeted osteoclast precursors and promoted the osteoclast phenotype in a TNF-independent manner in the presence of permissive levels of RANKL. IL-1 is able to induce RANKL expression by stromal cells and directly stimulate osteoclast precursor differentiation under the aegis of p38 MAPK. Thus, IL-1 mediates the osteoclastogenic effect of TNF by enhancing stromal cell expression of RANKL and directly stimulating differentiation of osteoclast precursors.
SUPER-SUPERLATIVE FLATTERY.
Journal: JAMA (1903)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 18006: Functional Effects of a Missense Common Variant in Neuregulin-1 Associated With Low Ejection Fraction and Sudden Cardiac Death
Authors: Adriana Huertas-Vazquez, Bing Xu, Kyndaron Reinier, Carmen Teodorescu, Audrey Uy-Evanado, Kumar Narayanan, Karen Gunson, Jonathan Jui, TingTing Hong, Robin M Shaw, Sumeet S Chugh
Journal: Circulation (2015)

Objective: To investigate the functional effects and genotype-phenotype correlation of a coding variant within the Neuregulin-1 gene (NRG1), which we previously identified from a community-based study of sudden cardiac death (SCD). Methods: The Missense variant Met286Thr within NRG1 was characterized by transfecting NRG1 wild type and mutant in HEK293 cells with a tag placed on the extracellular domain for assessment of membrane expression. To study genotype-phenotype correlations, we performed a case-case analysis comparing SCD carrier cases of the risk allele (n=384) vs. non SCD carrier cases (n=888). A total of 1,272 SCD cases of European descent were included in the study. Regression models adjusted for age and sex were tested to evaluate the correlation of the risk allele and clinical variables obtained ECGs and Echocardiograms of SCD cases. Results: We found that, unlike wild type NRG1, the Met286Thr variant did not traffic to the cell membrane (Figure), indicating defects in antegrade protein transport. We also found that in the subset of SCD cases with echocardiograms available (n=253), carriers of the risk allele were more likely to present with low ejection fraction (LVEF ≤35%) compared with the non-carrier cases (P=0.02, OR= 2.26 [1.14-4.5]. Other investigated risk factors such as QT prolongation, QRS duration, heart rate, left ventricular hypertrophy and coronary artery disease were not significantly different (P&gt;0.05). Conclusions: We have identified a novel variant in the transmembrane domain of NRG1, which results in defective antegrade transport and is associated with SCD and low ejection fraction. These findings support a role for Met286Thr in trafficking pathways leading to both functional compromise and ventricular arrhythmogenesis.
Prediction of Underachievement in Kindergarten Children
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
SYNERGISTIC ACTION OF HEMOPHILUS INFLUENZAE SUIS AND THE SWINE INFLUENZA VIRUS ON THE CHICK EMBRYO. II
Authors: Frederik B. Bang
Journal: The Journal of Experimental Medicine (1943)

Blood cultures of embryos killed by the synergistic action of swine influenza virus and Hemophilus influenzae suis are consistently negative, and embryos infected with swine influenza virus may be killed both by filtered extracts of frozen and dried Hemophilus and by suspensions of heat-killed bacteria. The addition of Hemophilus to the chorioallantoic membrane of embryos infected with swine influenza virus causes the virus to spread from the membrane to the allantoic fluid and embryo. This spreading effect also obtains when a purified preparation of hyaluronidase is used instead of Hemophilus, but it is unaccompanied by a comparable increase in mortality. It is probable that the spread of the virus produced by the bacteria is only partly responsible for the development of the complex infection and that products of these organisms other than the spreading factor play a large part in the mortality of embryos receiving the combination of virus and bacterium.
Effect of non‐pulsatile renal blood flow on plasma erythropoietin
Authors: Brian Krafte‐Jacobs
Journal: American Journal of Hematology (1998)

Erythropoietin is a hormone responsible for regulation of red blood cell production. Circulating erythropoietin values are regulated by renal oxygen supply, which is determined by hemoglobin concentration, hemoglobin oxygen saturation, and renal blood flow. Previous animal and human studies regarding erythropoietin regulation have assumed pulsatile renal blood flow. During cardiopulmonary bypass, non-pulsatile renal perfusion has been shown to result in decreased glomerular filtration rate and decreased renal blood flow in comparison to pulsatile perfusion. Repair of congenital heart disease during cardiopulmonary bypass is an attractive circumstance in which to study the effect of non-pulsatile blood flow on erythropoietin production. The hypothesis in this study was that non-pulsatile perfusion would result in increased erythropoietin production because of decreased renal oxygen supply. Fourteen children with congenital heart disease and without preoperative renal insufficiency or anemia were enrolled in the study. All patients underwent cardiopulmonary bypass with non-pulsatile flow. In addition, 10 control patients without congenital heart disease were enrolled. Six cardiopulmonary bypass patients had 1.5- to 6-fold increases in plasma erythropoietin concentrations from baseline. These patients had longer cardiopulmonary bypass times, more commonly performed under low flow deep hypothermic conditions. The remaining 8 patients with congenital heart disease, and all control patients, did not develop increased postoperative erythropoietin concentrations. The conditions under which cardiopulmonary bypass are performed appear to influence postoperative circulating erythropoietin concentrations. Am. J. Hematol. 57:144–147, 1998. © 1998 Wiley-Liss, Inc.
Book Review Clinical Dietetics . A Textbook for Physicians, Students and Dietitians. By Harry Gauss, M.S., M.D., F.A.C.P., Instructor in Medicine, University of Colorado, School of Medicine, assisted by E. V. Gauss, B.A., formerly Assistant Dietitian, Presbyterian Hospital, Denver, Colorado. Illustrated. St. Louis. The C. V. Mosby Company. 490 pages. Price $8.
Journal: New England Journal of Medicine (1931)
THE ABDERHALDEN REACTION
Journal: JAMA (1918)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Massachusetts Medical Society
Authors: Robert J. Haggerty
Journal: New England Journal of Medicine (1957)

APPLICANTS FOR FELLOWSHIPPublished in Accordance with the Provisions of Chapter V, Section 2, of the By-Laws Bristol NorthBrown, Bradford Russell, 49 Central Street, Mansfield.Boston University School of Medicine, 1955.J. Allen Bryer, Jr., M.D., Secretary 170 North Washington Street, North AttleboroBristol SouthHoward, Bertram Elliott, 251 Hawthorn Street, New Bedford.Tufts University School of Medicine, 1947.Howard, William John Thomas, 100 Madison Street, New Bedford.Guy's Hospital Medical School, University of London Faculty of Medicine, 1939.Sponsor: Dr. Theodore Ambadgis, 258 Walnut Street, New Bedford.Moe. Robert H., 151 Rock Street, Fall River. University of Chicago . . .
Prognostic significance of diabetes in patients with cirrhosis
Authors: Giampaolo Bianchi, Giulio Marchesini, Marco Zoli, Elisabetta Bugianesi, Andrea Fabbri, Emilio Pisi
Journal: Hepatology (1994)

Alterations in carbohydrate metabolism are frequently observed in cirrhosis, and approximately 15% to 30% of patients have overt diabetes. In a retrospective and prospective study in cirrhosis, we analyzed the prognostic significance of diabetes, which was defined as the presence of hyperglycemia and overt glycosuria that in most cases required dietary restrictions or active treatment. The clinical records of all patients with cirrhosis admitted to our department for the period 1980 to 1985 were reviewed in 1985 and 1986, and surviving patients were prospectively followed up until December 1991. Final status could be obtained in 354 (98 with diabetes) of 382 eligible patients; 110 were alive at the end of follow-up. Prognostic factors were identified by Kaplan-Meier analysis, followed by Cox's stepwise regression. The model identified, in sequence, albumin, ascites, age, encephalopathy, bilirubin, diabetes, and platelets as prognostic factors. The larger mortality rate in patients with diabetes was not due to complications of diabetes but to an increased risk of hepatocellular failure. Diabetes was no longer a risk factor as a covariate in a subgroup of 271 patients when varices were added but was again significant when patients who died of gastrointestinal bleeding were excluded. The presence of diabetes, clinically detectable and often requiring adequate treatment, is a risk factor for long-term survival in cirrhosis. (Hepatology 1994;20:119–125.)
BOOK REVIEW
Authors: ROBERT ORLOWSKI
Journal: JNCI Journal of the National Cancer Institute (1995)

Journal Article BOOK REVIEW Get access The Molecular Basis of Cancer John Mendelsohn , Peter M. Howley , Mark A. Israel , Lance A. Liotta , eds. Philadelphia : W. B. Saunders Company , 1995 . 574 pp., illus. $130. ISBN 0-7216-6483-0 ROBERT ORLOWSKI ROBERT ORLOWSKI Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 87, Issue 19, 4 October 1995, Page 1484, https://doi.org/10.1093/jnci/87.19.1484 Published: 04 October 1995
A new agent for the control of tinea versicolor. Acrisorcin (Akrinol)
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal