tbuckley/cabot-search huggingface dataset:
The Rational Clinical Examination-Reply
Authors: Drummond Rennie
Journal: JAMA (1992)

<h3>In Reply.</h3> —Concerning Dr Devitt's patient with a history and physical examination strongly suggesting deep-vein thrombosis and pulmonary embolism, both of us (as well as the chief of one of our hospital's thromboembolism service) would have started heparin "on spec" at the conclusion of our examination. However, given the imperfect specificity of her symptoms and signs (which will be the topic of a later overview in this series) and in light of the risks of anticoagulation and of labeling her a vasculopath, we also would have ordered one of the noninvasive tests for deep-vein thrombosis. If that initial investigation was positive, we would have stopped testing, continued her heparin, and prepared to switch her treatment over to long-term therapy with warfarin sodium. Only if noninvasive testing for deep-vein thrombosis was negative would we have proceeded to lung scanning or invasive testing. Finally, if we found the above course of action
Diabetic Neuropathy
Authors: Abraham Rudy
Journal: New England Journal of Medicine (1945)

THE frequency of neurologic abnormalities, particularly pain and paresthesias, in patients with diabetes mellitus prompted early observers to attribute the diabetes to a lesion of the nervous system. De Calvi1 in 1864 was the first to consider that the diabetes might be the cause of the neurologic symptoms. Auché,2 in a review of the literature published in 1890, stated that in diabetic patients all the nerves except those of the bladder and rectum could be involved. Woltman and Wilder3 in 1929 found only 42 reports, none of them between 1908 and 1928, of a pathologic examination of the spinal cord . . .
Assessing the impact of a targeted electronic medical record intervention on growth factor usage in cancer patients.
Authors: Jordan Bernens, Kara Hartman, Brendan F. Curley, Jane Rogers, Sijin Wen, Jame Abraham, Michael David Newton
Journal: Journal of Clinical Oncology (2014)

e17647 Background: Patients receiving chemotherapy are at risk for febrile neutropenia following treatment. The American Society of Clinical Oncology (ASCO) and National Comprehensive Cancer Network (NCCN) recommend screening patients for risk of febrile neutropenia and risk stratification based on likelihood of febrile neutropenia events. Prophylactic growth factors (G-CSF) should be used in patients receiving high-risk regimens or intermediate-risk regimens with individual risk factors. The impact of an electronic medical record system (EMR) implementation on compliance with G-CSF support guidelines has not been studied. Methods: At West Virginia University/Mary Babb Randolph Cancer Center we conducted an IRB approved retrospective chart review of cancer patients receiving chemotherapy from January 1, 2007 to August 1, 2008 (pre-EMR) and January 1, 2011 to December 31, 2011 (post-EMR). We reviewed the chemotherapy regimens and patient risk factors for developing febrile neutropenia, and determined if the G-CSF usage was consistent with guideline recommendations. Results: Compliance with prophylactic G-CSF guidelines was 75.6% in the post-EMR arm, compared to 67.5% in the pre-EMR arm (p=0.041, chi-square). The post-EMR data of 1,042 new chemotherapy initiations results are shown in the table. The appropriateness of usage in high and low risk patients were the most compliant, as G-CSF orders were built into chemotherapy plans of high risk regimens and omitted from low risk regimens. Conclusions: Appropriate prophylactic G-CSF usage can be improved when orders are integrated into standard chemotherapy order sets in an EMR. An area of further improvement would include automatic identification of individual risk factors by the EMR. G-CSF indicated Not indicated High risk Intermediate risk with risk factors Intermediate risk without risk factors Low risk G-CSF usage 89.1% 58.7% 26.2% 19.3%
Rupture of the right ventricle
Authors: D. B. Shires
Journal: JAMA (1968)

A rupture of the right ventricle was associated with isolated myocardial infarction of this ventricle. According to a review of the medical literature, this is a rare condition, most ruptures of the right ventricle either being traumatic in origin or following extensive infarction of the left ventricle or interventricular septum or both of the latter.
08.28 The prognostic value of iga autoantibodies (rheumatoid factor and acpa) for prediction of the therapeutic response to anti-tnf therapy in patients with rheumatoid arthritis
Authors: Daniela Sieghart, Paul Studenic, Farideh Alasti, Thomas Horn, Helmut Haslacher, Daniel Aletaha, Josef Smolen, Günter Steiner
Journal: Annals of the Rheumatic Diseases (2017)

<h3>Background and aim</h3> Anti-citrullinated protein antibodies (ACPA) and rheumatoid factor (RF) are important diagnostic markers in rheumatoid arthritis (RA). These antibodies are predominantly of the IgM (RF) or IgG (ACPA) isotype while the diagnostic value of IgA antibodies appears to be limited. However, IgA autoantibodies might have some prognostic value. This study aimed to investigate the predictive value of RF and ACPA IgA antibodies regarding response to treatment in patients with RA. <h3>Methods</h3> 255 patients who had undergone at least one treatment with TNF inhibitors were tested for the presence of IgA-RF and IgA-ACPA by EliA (Thermo Fisher Scientific). IgM-RF and IgG-ACPA were routinely measured by nephelometry and the anti-CCP assay, respectively. To define response to therapy SDAI50 and ACR20 responses were calculated. <h3>Results</h3> Among the 255 patients 114 (44.7%) were found to be IgA-RF positive: 12 of them were negative for IgM-RF and 6 patients were double negative for IgM-RF and IgG-IgG. IgA-ACPA were detected in 79 (31%) patients and almost all of them had also IgG-ACPA. Together, 49% of the patients had at least one type of IgA antibody. In total, 59% of RA patients were positive for RF by nephelometry. Testing for IgA-RF did identify additional 5% of RF positive patients and might therefore have some added diagnostic value. Remarkably, the percentage of patients showing a SDAI50 response to anti-TNF treatment was significantly lower in patients positive for IgA-RF and/or IgA-ACPA (p&lt;0.0001) compared to IgA-negative patients among whom 58% showed a SDAI50 response. Patients positive for IgA-ACPA but negative for IgA-RF had the lowest response rate with only one out of nine patients showing a response. Similar results were obtained when ACR20 was used as response criterium. In contrast, no difference between the groups was observed with respect to treatment with methotrexate and other synthetic drugs. <h3>Conclusion</h3> IgA antibodies were found in approximately 50% of the tested patient collective and identified additional 5% of RF positive patients. IgA-RF and particularly IgA-ACPA appear to have predictive value regarding the therapeutic response to TNF inhibitory biological drugs and could help in further stratification of RA patients and therapeutic decision making.
Poststreptococcal Glomerulonephritis
Authors: Lawrence V. Perlman
Journal: JAMA (1965)

Despite many reports regarding the apparent benign prognosis of acute poststreptococcal glomerulonephritis in children,<sup>1-4</sup>there remains some question about the relationship of this disease to chronic nephritis.<sup>5-9</sup>While many observers have concluded that the two diseases represent distinct and often unrelated entities, recent evidence, primarily from renal biopsies in adults, indicates that certain cases of chronic glomerulonephritis are the results of acute poststreptococcal disease which has failed to heal.<sup>9-11</sup>Many previous studies have been deficient because of inadequate follow-up, poor sampling, and the inclusion of diseases that were not clearly acute poststreptococcal glomerulonephritis. Because of these inadequacies, particularly with regard to precise definition of etiology of the acute disease, we observed a large group of children who had been clearly afflicted with acute poststreptococcal glomerulonephritis in 1953. One-hundred percent (61) of the surviving persons involved in a well-defined epidemic of streptococcal infection with a nephritogenic strain (Redlake
Queries and Minor Notes
Journal: JAMA (1923)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Conflicts of Interest and Independent Data Analysis in Industry-Funded Studies--Reply
Authors: P. B. Fontanarosa
Journal: JAMA (2005)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Tardive Dyskinesia
Authors: Michael Mack
Journal: JAMA (2004)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
TUBERCULAR PERICARDITIS.
Authors: C. F. McGAHAN
Journal: JAMA (1901)

This is a disease much more prevalent than has heretofore been generally accepted. A great many cases of obscure heart trouble in the anemic when we find no valvular disease, and when there are no marked, but certain masked symptoms of the disease, is due to tubercular pericarditis. Especially is this true if the patient later begins to lose weight and assume a cachectic appearance. Tubercular pericarditis generally progresses insidiously. It is communicated to the pericardium through the lymphatics, arterial or venous systems, and from that tends to extend to the peritoneum and other serous membranes. It is difficult to diagnose the disease as tubercular pericarditis in contradistinction to the non-tubercular pericarditis, unless it is secondary to a demonstrable tubercular lesion. However, if we are in doubt we can examine some of the aspirated fluid for the tubercle bacilli. If our search were negative we could not be positive that
Letter: Tolamolol in treatment of angina pectoris.
Authors: H Waal-Manning, F Simpson
Journal: BMJ (1975)

stated) and Morgan et al.4 also noted a rise in blood pressure in a few cases.Thorpe9 reported a rise in blood pressure (to 240/140 Hg) in a -patient who itook about 500 mg of pindolol in a suicide attempt.It is difficult to estimate exactly ihow often a hypertensive effect ooears, but our ex- perience with 260 patients treated with pin- dolol suggests that it may occur in about 5 % of cases.We ibelieve that pindolol is a useful and effeeive drug but that -the initial dosage should be low ,(for example, 2 5-5 0 mg twice daily) and that if dosages above 25-40 mg daily seem to be ineffective, then dose reduction should be tried.The 'blood pressure may then fall to satisfactory levels.If it remains unchanged, or if it falls but is still un- satisfactory, then somne other drug should be added.-Weare, etc.,
2010 ACNM Annual Meeting Resident Abstracts
Journal: Clinical Nuclear Medicine (2010)

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The efficacy of pacing therapies for treating atrial tachyarrhythmias in patients with ventricular arrhythmias receiving a dual-chamber implantable cardioverter-defibrillator Stuart W. Adler, II, Christian Wolpert, Eduardo N. Warman, Shailesh K. Musley, Jodi L. Koehler, David E. Euler. Medtronic, Inc., Minneapolis, MN
Journal: Journal of the American College of Cardiology (2001)
HOW SHALL THE NEW REMEDY BE RECEIVED.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
X-Ray Operation.
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Awakening
Authors: Blair P. Grubb
Journal: Annals of Internal Medicine (1997)

Ad Libitum15 August 1997AwakeningBlair P. Grubb, MDBlair P. Grubb, MDMedical College of Ohio; Toledo, OH 43699-0008Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-127-4-199708150-00014 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail There were so many admissions that night that I had begun to lose count-and my temper. A seasoned intern, I had learned well the art of the quick, efficient workup. Shortcutting had become a way of life. Morning was coming and, with it, my day off. All I wanted was to be done. My beeper sounded. I answered it. I heard the tired voice of my resident say, “Another hit, some 90-year-old gomer with cancer.” Swearing under my breath, I headed to the room. An elderly man sat quietly in his bed. Acting put upon, I abruptly launched into my ... Author, Article, and Disclosure InformationAffiliations: Medical College of Ohio; Toledo, OH 43699-0008Corresponding Author: Blair P. Grubb, MD, Division of Cardiology, Medical College of Ohio, 3000 Arlington Avenue, Box 10008, Toledo, OH 43699-0008. Previousarticle Advertisement FiguresReferencesRelatedDetails Metrics 15 August 1997Volume 127, Issue 4Page: 331KeywordsCyclic adenosine monophosphateElderlyEmotionsSleepSmellSystematic reviews ePublished: 15 August 2000 Issue Published: 15 August 1997 Copyright & PermissionsCopyright © 1997 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
ABSTRACTS
Authors: STANFORD WESSLER
Journal: Circulation (1962)

Experiments were performned on dogs to deter- nmine the extent to which the coronary circula- tion affects the myocardial contractility and cardiac size.Heart failure produced by pulmo- nary artery constriction was a consequence of decreased coronary blood flow.Marked func- tional improvement was obtained by increasing coronary blood flow by means of a veno-arterial shunting procedure.After a period of the shunt- ing procedure, some of the animals acquired the capacity to maintain good cardiac function even when the shunt was discontinued.The coronary blood flow influenced the heart size, strength of contraction, and adaptive mechanisms.Clinical application of these principles was described in a patient with myocardial infaretion and pro- longed shock who responded favorably to a veno- arterial shunt.KALMANSOHN
Symbols used in the Table of Contents
Authors: Yong-Jun Liu, Carsten Schmidt-Weber, ¨beccel Akdis, Cezmi Akdis, Susan Prescott, Bengt Bjo ¨rkste ´n, Javier Chinen, William Shearer, Ngoc Ly, Juan Celedo ´n
Journal: Journal of Allergy and Clinical Immunology (2007)
Obstetrícia operatória.
Journal: JAMA (1933)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal