tbuckley/cabot-search huggingface dataset:
One-to-one tachycardias do not endanger safe arrhythmia detection due to imitation of supraventricular tachyarrhythmias: Results with two new dual-chamber detection algorithms Christian Wolpert, Werner Jung, Susanne Herwig, Rainer Schmipf, Kyung-Mi Jeong, Alexander Yang, Berndt Luederitz. University of Bonn, Bonn, Germany
Journal: Journal of the American College of Cardiology (2001)
Metabolic effects of dietary fructose and sucrose in types I and II diabetic subjects
Authors: J. P. Bantle
Journal: JAMA (1986)

To learn more about the metabolic effects of dietary fructose and sucrose, 12 type I and 12 type II diabetic subjects were fed three isocaloric (or isoenergic) diets for eight days each according to a randomized, crossover design. The three diets provided, respectively, 21% of the energy as fructose, 23% of the energy as sucrose, and almost all carbohydrate energy as starch. The fructose diet resulted in significantly lower one- and two-hour postprandial plasma glucose levels, overall mean plasma glucose levels, and urinary glucose excretion in both type I and type II subjects than did the starch diet. There were no significant differences between the sucrose and starch diets in any of the measures of glycemic control in either subject group. The fructose and sucrose diets did not significantly increase serum triglyceride values when compared with the starch diet, but both increased postprandial serum lactate levels. We conclude that short-term replacement of other carbohydrate sources in the diabetic diet with fructose will improve glycemic control, whereas replacement with sucrose will not aggravate glycemic control. (<i>JAMA</i>1986;256:3241-3246)
Muscle quality as assessed by computed tomography-derived skeletal muscle density is associated with 28-day mortality in mechanically ventilated critically-ill patients with cirrhosis
Authors: Jaya Benjamin, Harshita Tripathi, Shalini Thapar, Varsha Shasthry, Rakhi Maiwall, Vijayraghavan Rajan, Vandana Saluja, Dr. Prashant Mohan Agarwal, Lalita Mitra, Guresh Kumar, Dr. Puneet Puri, Yogendrakumar Joshi, Shiv Kumar Sarin
Journal: Journal of Hepatology (2020)
Report of the Council on Constitution and Bylaws
Journal: JAMA (1962)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Syphilis
Authors: G. Marshall Crawford
Journal: New England Journal of Medicine (1946)

THE use of penicillin in syphilotherapy has become so widespread and the volume of literature regarding this drug so voluminous that this year's progress report on syphilis is being presented in slightly different fashion. A separate main division is devoted to penicillin and placed at the end of the report.Public HealthLittle literature has appeared during the past year regarding the public-health aspects of syphilis. This may be due to some degree of optimism resulting from the remarkable reduction in the incidence of venereal disease during World War II. Never in history has any nation been able to accomplish . . .
Evaluation of Therapeutic Methods for Chronic Schizophrenia
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Treatment of Displacement of the Proximal Radial Epiphysis
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Effect of an Antimitotic Agent Colchicine on Thioacetamide Hepatotoxicity
Authors: Raja S. Mangipudy, Prathibha S. Rao, Harihara M. Mehendale
Journal: Environmental Health Perspectives (1996)

In an earlier study we established that timely and adequate tissue repair response following the administration of a six-fold dose-range of thioacetamide (TA; 50, 150, and 300 mg/kg) prevented progression of injury and led to recovery and animal survival. Delayed and attenuated repair response after the 600 mg/kg TA dose resulted in a marked progression of injury and 100% lethality. The objective of the present study was to further scrutinize this concept in an experimental protocol in which we hypothesized that a selective ablation of the tissue repair response should lead to lethality from the nonlethal, moderately toxic doses of 150 and 300 mg/kg TA. In this study we investigated the effect of the antimitotic agent colchicine (CLC, 1 mg/kg) on the outcome of TA hepatotoxicity. Male Sprague-Dawley rats (175-225 g) were injected intraperitoneally (ip) with 150 and 300 mg/kg TA. We assessed liver injury by serum enzyme elevations and histopathology. Tissue regeneration response was measured by 3H-thymidine incorporation into hepatonuclear DNA and by proliferating cell nuclear antigen (PCNA) assay. S-Phase stimulation, as indicated by 3H-thymidine incorporation, was noted at 36 and 48 hr following the administration of 150 mg/kg TA, whereas with the 300 mg/kg TA S-phase stimulation was elicited at 48 hr following treatment. Therefore, two doses of CLC (30 hr and 42 hr, 1 mg/kg, ip) were administered to the 150 mg/kg treated group while a single dose of CLC (42 hr, 1 mg/kg, ip) was administered to the 300 mg/kg group. CLC treatment resulted in 100% lethality in both groups. Thus, CLC administration converted nonlethal doses into lethal doses. The 150 mg/kg TA dose was then chosen to further investigate the underlying mechanism. Rats treated with TA alone recovered from injury by 36-48 hr while CLC treatment resulted in a progression of injury as indicated by serum enzyme elevation and histopathology. Tissue repair, as evidenced by 3H-thymidine incorporation and PCNA studies explained this dichotomy. Antimitotic intervention with CLC resulted in a significantly diminished repair response leading to unrestrained progression of injury and lethality even from nonlethal doses. This model demonstrates the critical role of tissue repair response in determining the final outcome of toxicity.
Book Review Traité de biocolloïdologic. Tome V. État colloïdal et médecine . Fascicule 1. Le Sang. 151 pp. Fascicule 2. Liquides et tissus organiques. 299 pp. W. Kopaczewski. Paris: Gaulhier-Villais, 1938. 160 Fr. fr.
Journal: New England Journal of Medicine (1940)
CONSERVATISM IN THE TREATMENT OF THROMBO-ANGIITIS OBLITERANS
Journal: JAMA (1934)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Genetic Adaptation of Bacteria to Halogenated Aliphatic Compounds
Authors: Dick B. Janssen, Jan R. van der Ploeg, Frens Pries
Journal: Environmental Health Perspectives (1995)

The bacterial degradation and detoxification of chlorinated xenobiotic compounds requires the production of enzymes that are capable of recognizing and converting compounds which do not occur at significant concentrations in nature.We have studied the catabolic route of 1,2-dichloroethane as an example of a pathway for the conversion of such a synthetic compound.In strains of Xanthobacter and Ancylobacter that have been isolated on 1,2-dichloroethane, the first catabolic step is catalyzed by a hydrolytic haloalkane dehalogenase.The enzyme converts 1,2-dichloroethane to 2- chloroethanol but is also active with many other environmentally important haloalkanes such as methylchloride, methylbromide, 1,2-dibromoethane, epichlorohydrin, and 1,3-dichloropropene.Further degradation of 2-chloroethanol proceeds by oxidation to the carboxylic acid and dehalogenation to glycolate.The aldehyde dehydrogenase prevents toxicity of the reactive chloroacetaldehyde that is formed as an intermediate and is necessary for establishing a functional 2-chloroethanol degradative pathway in a strain that is not capable of growth on this compound.
Defined Diets and Childhood Hyperactivity
Journal: JAMA (1982)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Restoration of function in industrial low back injury
Journal: JAMA (1988)

<h3>To the Editor.</h3> —Although I would like to believe the findings of the recent article by Mayer et al<sup>1</sup>concerning functional restoration of patients with low back injury, this submission has significant flaws in methodology. The most important flaw is the assignment of patients to treatment and nontreatment groups on the basis of whether their insurance plan would reimburse the costs of the three-week rehabilitation program, ranging from $5000 to $9000. Although we are assured that the two groups are comparable, the data presented in tabular form neglect several important variables. Were the two groups comparable in regard to specific jobs being performed, previous frequency of visits to health care professionals, or prior training that might enable them to seek employment in a more sedentary industry? Since the nontreatment group was not objectively evaluated in terms of degree of disability, were the two groups comparable on this basis? Patients
Alone
Authors: David J. Baylink
Journal: JAMA (1985)

He methodically took his set of keys from his left rear pocket, selected the key for the car door, unlocked it, and reflected on whether anyone who had contributed to the craft of keymaking had done what he was about to do. He hoped not. He continued to ready himself for his trip. He placed his camping gear in the back seat of the brown Toyota. There was enough food to last perhaps three days. He locked his apartment door and felt tidy and responsible, but he left no note. He got into his car, turned on the ignition, looked back once, and headed for Highway 15E. He knew the route because he had visited the Mojave Desert only a month before. This, however, was to be a very different trip. As he drove through the Cajon Pass, he smiled philosophically as he caught himself feeling the urge to lift
ABSTRACTS
Authors: PAUL M. ZOLL
Journal: Circulation (1965)

The authors report the case histories of two men (age 36 and 41) who decided to lose weight, stop smoking, and, for the first time in their lives, run daily for three to five miles.Examina- tion prior to the onset of this regimen revealed no evidence of cardiac disease and there had been no previous history of rheumatic fever nor episodes suggestive of myocarditis.Both pa- tients later developed partial heart block of the Wenckebach variety, which disappeared within 3 months after the patients had ceased the vig- orous exercise.Following resumption of the daily running, the arrhythmia recurred in one patient but not in the other whose second train- ing period was less strenuous.It was then deter- mined that one patient had a history of "influ- enzal myocarditis" and it was therefore impossible to rule out the presence of organic cardiac disease.However, this patient continued his daily run of three miles without incidence.Manifesta- tions of excessive vagal tone were discovered as a possible cause of the arrhythmia in the second patient.The authors concluded that the develop- ment of identical arrhythmias in both patients and the subsequent presence of ventricular extra- systoles in one of the patients, suggested that partial AV heart block associated with the Wenckebach phenomenon may not be rare in athletes and, that the absence of previous case reports (especially in distance runners) may be 622
In Brief
Authors: K. Arnold
Journal: JNCI Journal of the National Cancer Institute (2003)

In Brief Breast Cancer Screening Cost-Effective in Older WomenBreast cancer screening every 2 years in women age 65 and older reduces mortality at reasonable costs for otherwise healthy women, concluded a working group for the U.S. Preventive Services Task Force (USPSTF) using a statistical cost-effectiveness model.The USPSTF recommends that women age 40 and older be screened with mammography for breast cancer every 1 to 2 years.However, the recommendation was based on studies that included few women older than age 65, so it remains unclear whether screening is cost-effective for women in this age group.Members of USPSTF's Cost Work Group reviewed 10 studies that included economic evaluations of breast cancer screening and included data for older women.They found that, overall, screening women ages 65 to 80 every 2 years resulted in incremental costs of about $34,000 to $88,000 per life-year saved compared with stopping screening at age 65.The authors note, however, that the harms begin to outweigh the benefits in the sickest women, such as those with dementia or those with a condition that limits their life expectancy to 5 years.
NEW LIGHT ON MAMMARY CANCER
Journal: JAMA (1962)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Rubaiyat—a Persian Quatrain.
Journal: JAMA (1898)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hospital News.
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Facial Hyperhidrosis
Authors: George D. Gammon
Journal: JAMA (1962)

<h3>To the Editor:—</h3> The note on "Facial Hyperhidrosis" by Drs. Sankstone and Cornbleet (<i>JAMA</i><b>179</b>:571 [Feb. 17] 1962) which stated the condition was only temporarily relieved by stellate bloc recalls a patient with a similar, but unilateral condition in which treatment was successful. This young girl sweated for many years so profusely that she carried a bath towel to mop her face and scalp. At operation, in which it was planned to remove the stellate ganglion, this was found to be riding up over a large transverse process of the seventh cervical vertebra. This was excised, leaving the nerve supply intact. Permanent relief followed.
With the Eighth Army in the Field--I
Authors: C. Donald
Journal: BMJ (1944)

To journey through the Western Desert, into Tripolitania and Tunisia, across to Sicily, and up into Italy with the Eighth Army was a great privilege.No one could travel in that fine company without an ever-present pride in the British fighting- man.His feats of arms are well chronicled.To those travel- ling closely in his wake the wonder ever grew at the sight of the obstacles he overcame and the defences he stormed.Added to these he had the changing yet constant privations of the field and of the front line, heat and sandstorms, cold and mud, forced marches and tedious delays, pestilential flies, shortage of water, monotonous though ample rations, and other lesser trials.He deserved then, when he was wounded, the best that could be offered.
Risk Factors for Diseases of Ileal Pouch–Anal Anastomosis After Restorative Proctocolectomy for Ulcerative Colitis
Authors: Bo Shen, Victor W. Fazio, Feza H. Remzi, Aaron Brzezinski, Ana E. Bennett, Rocio Lopez, Jeffrey P. Hammel, Jean-Paul Achkar, Charles L. Bevins, Ian C. Lavery, Scott A. Strong, Conor P. Delaney, Wendy Liu, Marlene L. Bambrick, Kerry S. Sherman, Bret A. Lashner, Patrick Kamath
Journal: Clinical Gastroenterology and Hepatology (2006)