tbuckley/cabot-search huggingface dataset:
Radiation Doses Associated With Cardiac Computed Tomography Angiography—Reply
Authors: Jörg Hausleiter
Journal: JAMA (2009)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE LOCAL AND GENERAL SERUM TREATMENT OF CUTANEOUS ANTHRAX
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The effect of intracoronary radiation on the long-term outcome of diabetic patients with in-stent restenosis Luis Gruberg, Ron Waksman, Roxana Mehran, Alexandra J. Lansky, R. Lawrence White, Rosanna C. Chan, Bill G. Bass, Lowell F. Satler, Gary S. Mintz, Augusto D. Pichard, Kenneth M. Kent. Washington Hospital Center, Washington, DC
Journal: Journal of the American College of Cardiology (2001)
Investigations of the Therapeutic Research Committee of the Council on Pharmacy and Chemistry of the American Medical Association. Annual Report
Journal: JAMA (1924)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Risk Calculations for HIV Transmission From Infected Health Care Workers-Reply
Authors: C. Fordham von Reyn
Journal: JAMA (1993)

<h3>In Reply.</h3> —Dr Shelly agrees with our use of the binomial distribution to calculate the maximum probability of HIV transmission from an infected surgeon to a patient. As he points out, however, an error was made in our calculation: the correct 95% CI for zero per 1174 patients is 0 to 255 transmissions per 100 000 patients. Drs Gracely, St. John, and Yan arrive at similar figures. However, it is important to point out that the observed rate of transmission in our study was 0%. St. John and Yan suggest that our study may have underestimated the risk of HIV transmission. We believe our estimates were conservative. The surgeon may have been infected longer than we estimated: our risk exposure interview strongly suggested that he could not have been infected after 1978; he may have been infected before 1978. Furthermore, we did not use all operative procedures conducted by the
SAT0016 TH17 Cytokines Regulate Osteoclastogenesis in Rheumatoid Arthritis
Authors: H.-R. Kim, S.-H. Lee, H.-Y. Kim, S.-H. Lee
Journal: Annals of the Rheumatic Diseases (2015)

<h3>Background</h3> Th17 cells, which are defined by a selective interleukin (IL)-17 secretion, are considered as a distinct lineage of CD4+ helper T cells which are regulated by the other Th1 and Th2 cytokines. IL-17A is a dominant proinflammatory cytokine produced by the Th17 cells. IL-21, IL-22 and IL-26 are also produced by the Th17 cells. In RA, IL-17A induces the production of proinflammatory mediators, such as IL-1 and tumor necrosis factor (TNF)-a from synovial fibroblasts, macrophages, and chondrocytes. <h3>Objectives</h3> This study aimed to determine the regulatory effect of Th17 cytokines on the osteoclastogenesis in rheumatoid arthritis (RA). <h3>Methods</h3> The expression of IL-17 and RANKL was determined in synovial tissue, fibroblast-like synoviocytes (FLS) and synovial fluids of RA patients using immonohistochemical staining, ELISA and real-time PCR. The Th17 cytokines-induced RANKL expression was studied in RA FLS using real-time PCR, luciferase activity, and western blot. Human peripheral blood monocytes were cultured with M-CSF and Th17 cytokines, and then osteoclastogenesis was determined by counting the number TRAP-positive multinucleated cells. The osteoclastogenesis was also determined after human monocytes were co-cultured with IL-17-prestimulated FLS. <h3>Results</h3> There was significant correlation between RANKL and IL-17 levels in RA synovial fluid. After RA FLS were stimulated with IL-17, IL-21 and IL-22, the expression of RANKL mRNA increased and the IL-17-induced RANKL expression was decreased by the inhibition of Act1, TRAF6, NF-κB and the AP-1. Th17 cytokines and IL-17-prestimulated FLS induced osteoclastogenesis from monocytes in the absence of osteoblasts or RANKL. <h3>Conclusions</h3> Th17 cytokines have a dual effect on osteooclastogenesis in RA; direct induction of osteoclastogenesis from monocytes and upregulation of RANKL production in RA FLS. Th17 cytokines/RANKL axis could be a potential therapeutic target for bone destruction in RA. <h3>Disclosure of Interest</h3> None declared
GENERAL INDEX
Journal: JAMA (1910)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Author Index Vol. 78, 2009
Authors: Cheryl A. Cockram, Gheorghe Doros, John M. de Figueiredo, Thomas Karger, Nicoletta Sonino, Pio Peruzzi, Piero Porcelli, Antonello Bellomo, Roberto Quartesan, Mario Altamura, Salvatore Iuso, Ida Ciannameo, Massimiliano Piselli, Sandro Elisei, Giovanni A. Fava, Nicoletta Sonino, Giovanni A. Fava, Thomas N. Wise, Palmiero Monteleone, Cristina Serritella, Valter Milano, Arcangelo Di Cerbo, Francesco Blasi, Claudio Petrella, Mario Maj, Giovanni Nolfe, K. Domschke, Mark B. Powers, Paul M.G. Emmelkamp, John S. Ogrodniczuk, William E. Piper, Anthony S. Joyce, Allan A. Abbass, Michael Levin, Steven C. Hayes, Elisa Albieri, Dalila Visani, Emanuela Offidani, Fedra Ottolini, Chiara Ruini, Andrew A. Nierenberg, Diane Warden, Madhukar H. Trivedi, Stephen R. Wisniewski, Ira M. Lesser, Jeff Mitchell, G.K. Balasubramani, Maurizio Fava, Kathy Shores-Wilson, Diane Stegman, A. John Rush, R. Berger, M. Gelkopf, K. Pohle, T. Roehrs, V. Arolt, B.T. Baune, Raluca A. Topciu, Xi Zhao, Wan Tang, Marnin J. Heisel, Nancy L. Talbot, Paul R. Duberstein, M. Pasquini, L. Tarsitani, D. Piacentino, G. Moretti, C. Roscioli, C. Leone, M. Biondi
Journal: Psychotherapy and Psychosomatics (2009)
Letter: Dry mouth and dysglycemia
Authors: E. Cheraskin
Journal: JAMA (1974)

<h3>To the Editor.—</h3> Occasional published reference has been made concerning the relationship between diabetes mellitus and xerostomia (dry mouth). Conner et al<sup>1</sup>have studied this relationship in a more quantitative fashion. They reported recently that parotid salivary flow in an age- and sexmatched sample of 30 diabetics and 30nondiabetics is significantly different. The mean parotid flow in the diabetics was only one-fourth that of the controls, and the statistical significance of the mean difference in flow rate was less than the 1% confidence level (<i>P</i>&lt;.01). Scant attention, however, has been given to the possible association of xerostomia and overall carbohydrate metabolism (hyperglycemia, normoglycemia, and hypoglycemia).<sup>2</sup>Considering these three aspects of glycemia, there appears to be a distinct correlation between xerostomia and dysglycemia, both hyperglycemia and hypoglycemia (<i>J Am Geriatr Soc</i>12:337, 1964). In an age- and sex-paired analysis of 38 subjects, a classic three-hour glucose tolerance
Acanthosis nigricans and autoimmune reactivity
Authors: R. A. Sturner
Journal: JAMA (1981)

Acanthosis nigricans has been associated with malignant diseases and endocrinopathy. One of the cases reported herein and a review of 12 others suggest that the onset of acanthosis nigricans may predate a variety of classic autoimmune diseases. The other case being reported now, along with a literature review of 22 cases, suggests that acanthosis nigricans also may be associated with disordered immunoreactivity not fitting any clinically recognizable syndrome. (<i>JAMA</i>1981;246:763-765)
Diagnosis of Small-pox. A Correction
Journal: BMJ (1924)

I hal a rather curious case a few days ago of a weaver who, in the act of sucking up thread from the shuttle, found that the thread had become attached in her throat atnd could not be removed.When I sa%w the patient she had the thread hanging out of her mouth and tba other end was firmly fastened in what I surmised must be her larynx.H,owever, on examining the throat, I found that the distal end of the thread was anchored on to a circumvallate papilla at the roct of the tongue.Pulling quite forcibly would not dislodge the thread, so I perforce had to seize the papilla in artery
Bilirubin Metabolism
Authors: Roger Lester, Rudi Schmid
Journal: New England Journal of Medicine (1964)

BILIRUBIN is a yellow tetrapyrrol derived from the catabolism of hemoglobin and secreted by the liver into the gut. For over a hundred years the characteristics and behavior of this bile pigment have been of abiding interest to both clinicians and research investigators. Since the beginning of this century, the physical and chemical properties of bilirubin and its derivatives have been elaborated through the work of Fischer, Siedel, Lemberg, Watson, Gray and others. More recently, the introduction of isotopic technics1 2 3 4 and the elucidation of mechanisms of hepatic conjugation5 6 7 8 have provided the impetus for major advances in the area of bilirubin . . .
Incorrect Author Contributions
Authors: Anjali Jain, Jaclyn Marshall, Ami Buikema, Tim Bancroft, Jonathan Kelly, Craig Newschaffer, Marshall Jain
Journal: JAMA (2016)

Fahad Razak, MD, MSc; Daniel J. Corsi, PhD; Arthur S. Slutsky, MD, MASc; Anura Kurpad, MD, PhD; Lisa Berkman, PhD; Andreas Laupacis, MD, MSc; S. V. Subramanian, PhD
Grandmother
Authors: M. Therese Southgate
Journal: JAMA (2003)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Reticulum Cell Sarcoma of Skin
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hepatitis B virus subtypes and hepatitis C virus genotypes in patients with chronic liver disease in Nepal
Authors: S Shrestha
Journal: Hepatology (1994)

A total of 145 patients with chronic liver disease, including 20 with chronic hepatitis, 63 with cirrhosis and 62 with primary hepatocellular carcinoma from Nepal were tested for markers of hepatitis B virus or hepatitis C virus infection. HBsAg was detected in 57 (39%) and hepatitis C virus RNA in 12 (8%); the cause of liver disease was not known in the remaining 76 (52%). HBsAg was found in 5 (1.3%) of 379 normal controls, whereas hepatitis C virus–associated antibodies were detected in 13 (3.4%), none of whom was positive for serum hepatitis C virus RNA. Subtypes of 102 HBsAg samples, from patients and asymptomatic carriers, were adw in 35 (34%), adr in 4 (4%) and ayw in 48 (47%); the remaining 15 (15%) were of atypical subtypes such as ad, ay and a. Of 12 hepatitis C virus RNA samples, genotype I was detected in 1, genotype II in 5 and genotype V in 1; the remaining five samples were not to be classified by polymerase chain reaction with primers specific for genotypes I to V deduced from hepatitis C virus core sequences, despite high hepatitis C virus RNA titers in all of them. Sequences of 192 amino acids in the entire E1 region of unclassifiable hepatitis C virus isolates from five patients differed from each other in 17% to 23%, and varied from reported isolates of defined genotypes in 13% to 44%. These results indicate that atypical subtypes of hepatitis B virus and novel genotypes of hepatitis C virus would prevail in Nepal. (HEPATOLOGY 1994;19:805–809.)
Observations on the " Code."
Authors: None E. S. B.
Journal: JAMA (1897)

New York, Oct. 31, 1897. <h3>To the Editor:</h3> —The "Code" is noble, a law irrevocable, supreme wherever the doctor wends his way, ruling an army of learned and cultured men. Its genesis is lost in antiquity. It is noble, but not more so than the unified profession whose ethics it formulates, failing only in so far as those whom it would govern are human, and to be human is to fail as well as to succeed. The " Sermon on the Mount " has been attacked, so has the Code. It has been said that a gentleman requires no "rule of conduct;" true, but all are not gentlemen, and so there is need for the rule of ethics as there is need for the "Sermon;" neither will be too old until the time has come when every man does unto his neighbor as he would be done by. However, it is not
Windows
Authors: Frank D. Campion
Journal: JAMA (1989)

It seems to be getting harder and harder for the layperson to make the necessary, crucial medical decisions only he or she can make. Costs have risen, of course. Ethical questions are more complex. And the growth of scientific technology has made many things more difficult to understand. The voice of common sense, of humane reason, does not come through with the strength we might like. Not that I have anything against the strides made in medicine. High-tech medicine stood me in good stead in my first brush with laryngeal cancer 10 years ago, and it seemed to be doing well in managing a recurrence that appeared last fall. But suddenly, this April, as I struggled to recover from radiation therapy, all of my energy, appetite, and strength seemed to go. A CT scan confirmed the worst suspicion: a new tumor was growing in my neck between the airway and
Preoperative portal vein embolization for extension of hepatectomy indications
Authors: T de Baere, A Roche, D Elias, P Lasser, C Lagrange, V Bousson
Journal: Hepatology (1996)

To render hepatectomy feasible in patients with an initially deficient volume of the future remnant liver (FRL), we redistributed portal blood flow rich in hepatotrophic substances toward the FRL. Redistribution was achieved with preoperative portal vein embolization (POPE) feeding the future resected liver. POPE was performed in 31 patients, under fluoroscopic guidance, via a percutaneous access. POPE was well tolerated and surgery was practicable in 24 patients without severe postoperative liver failure. Seven operations were cancelled, but only one due to insufficient hypertrophy of the FRL. FRL volume values were 90 to 560 mL (mean 260 mL) before POPE and 160–783 mL (mean 443 mL) after POPE, which represents a median increase of 79% ± 50%. Hypertrophy of the FRL was 90% ± 52% after 30 days with cyanoacrylate, 53% ± 6% after 43 days with Gelfoam, and 44% ± 30% after 35 days with coils. Slight shrinkage was obtained in the volume of the embolized liver, for which resection was planned. Overall survival was 2–62 months (mean 26 months), disease–free survival was 0–60 months (mean 19 months), and 7 patients are disease–free and alive 14 to 60 months (mean 43 months) after surgery. Although exclusively applicable in a limited subset of patients, POPE widens the possibilities of curative hepatectomies, because it induces sound hypertrophy of unembolized liver segments. Cyanoacrylate seems to ensure better and faster hypertrophy.
MEDICAL EDUCATION—PROGRESS OF TWENTY-TWO YEARS
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Irreversible Hypoglycemia
Authors: Ronald A. Arky
Journal: JAMA (1968)

The glucose-lowering action of alcohol augments that of other hypoglycemic agents and may induce severe hypoglycemia with irreversible neurological changes. Five insulin-dependent diabetics were hospitalized with severe hypoglycemia after an alcohol debauch. Three of the five had permanent damage to the nervous system, while the other two patients died without recovery from initial coma. Infusion of alcohol during a standard insulin tolerance test in six healthy subjects inhibited the usual rebound of glucose after hypoglycemia. Alcohol interferes with hepatic glyconeogenesis and induces hypoglycemia whenever giyconeogenesis is required to maintain normal glucose levels. Diabetics receiving other hypoglycemic agents should be warned about the blood glucose-lowering action of alcohol.