tbuckley/cabot-search huggingface dataset:
Correction
Journal: BMJ (1966)

Any Questions ?Bxms 35the pyramidal system.The manifestations are similar to Parkinson's syndrome.In the early stages the changes are reversible, but in more severe intoxication the damage is permanent.Workers should be examined before employment to exclude neurological disease.Routine examination should be carried out at regular intervals, say three to six months, so that symptoms may be detected as early as possible.Should they develop the workman should be removed from exposure.The presence of manganese in the atmo- sphere may be estimated by standard methods.Intoxication can be prevented by provision of appropriate enclosure methods and adequate ventilation to maintain the atmospheric concentration below the recom- mended threshold of 5 mg.per cubic metre of air.
Prosthesis At Surgery Aids Recovery
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Annual Meeting Actions of the AMA-RPS
Journal: JAMA (1992)

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Addresses, Papers and Discussions
Journal: JAMA (1896)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Phase I Evaluation of Prolonged-Infusion Gemcitabine With Mitoxantrone for Relapsed or Refractory Acute Leukemia
Authors: David A. Rizzieri, Adam J. Bass, Gary L. Rosner, Jon P. Gockerman, Carlos M. DeCastro, William P. Petros, David J. Adams, Mary J. Laughlin, Patti Davis, Traci Foster, Robert Jacobson, Herbert Hurwitz, Joseph O. Moore
Journal: Journal of Clinical Oncology (2002)

PURPOSE: To ascertain the maximum tolerated duration of infusion of gemcitabine at 10 mg/m 2 /min in combination with mitoxantrone at 12 mg/m 2 daily for 3 days in the treatment of acute leukemia. PATIENTS AND METHODS: Thirty-four patients were enrolled. Stratum I consisted of 26 patients, median age 50 years (range, 25 to 71 years), with relapsed or refractory leukemia. Stratum II contained eight patients, median age 62.5 years (range, 38 to 83 years), who had received fewer than three cycles of myelotoxic therapy for chronic myeloid leukemia or myelodysplasia that had evolved into leukemia. Patients received mitoxantrone at 12 mg/m 2 daily for 3 days. After the first mitoxantrone dose, gemcitabine was provided intravenously at 10 mg/m 2 /min with the duration adjusted by following a continuous reassessment model. RESULTS: Severe myelosuppression, and stomatitis or esophagitis were the most common hematologic and nonhematologic dose-limiting toxicities. Several patients developed febrile neutropenia, nausea, or vomiting. In both strata, the maximum recommended duration of infusion of gemcitabine was 12 hours (7,200 mg/m 2 ). The mean steady-state concentration of gemcitabine was 24.72 μmol/L and varied over a fivefold range among patients. Overall response rates in this phase I trial for strata I and II were 42% and 63%, respectively. CONCLUSION: Prolonged-infusion gemcitabine at a fixed dose rate of 10 mg/m 2 /min for 12 hours with 12 mg/m 2 /d mitoxantrone for 3 days is a tolerable induction regimen and achieves plasma concentrations sufficient for maximal intracellular activation. Stomatitis or esophagitis should be anticipated; however, this regimen may induce significant responses in patients with difficult-to-treat leukemias.
Incorrect Complication Description in Table
Authors: Samuel Wilkinson, Deepak Cyril, D Souza
Journal: JAMA (2014)

Barbara P. Yawn, MD, MSc, MSPH; George R. Buchanan, MD; Araba N. Afenyi-Annan, MD, MPH; Samir K. Ballas, MD; Kathryn L. Hassell, MD; Andra H. James, MD, MPH; Lanetta Jordan, MD, MPH, MSPH; Sophie M. Lanzkron, MD, MHS; Richard Lottenberg, MD; William J. Savage, MD, PhD; Paula J. Tanabe, PhD, RN; Russell E. Ware, MD, PhD; M. Hassan Murad, MD, MPH; Jonathan C. Goldsmith, MD; Eduardo Ortiz, MD, MPH; Robinson Fulwood, PhD, MSPH; Ann Horton, MS; Joylene John-Sowah, MD, MPH
Epitome of Skin Diseases
Journal: JAMA (1883)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Direct Pancreatoscopy
Authors: T. Kodama, Y. Tatsumi, R. A. Kozarek, J. F. Riemann
Journal: Endoscopy (2002)

Several imaging procedures, including transabdominal and endoscopic ultrasonography, computed tomography (CT), magnetic resonance imaging (MRI) and endoscopic retrograde cholangiopancreatography (ERCP), have been established for the diagnosis of pancreatic diseases. Among them, ERCP is the current gold standard for diagnosis of pancreatic cancer as well as other diseases involving the pancreatic duct. However, it may fail to differentiate strictures or intraluminal filling defects of the pancreatic duct. It may also fail to detect minimal change, and chronic pancreatitis may not be well visualized with contrast medium. Given these limitations, it is necessary to have a modality with a direct approach to the pancreatic duct. Based on this concept, Japanese endoscopists, including Takekoshi et al. [1], first developed peroral pancreatoscopy through the accessory channel of a duodenal fiberscope in 1975. However, this device proved unpopular in clinical use because of problems which included instrument expense, fragility, low visibility, and its relatively large diameter relative to the duodenal papilla.
Senior olympian
Authors: Marilyn Spievak Brodwick
Journal: The Lancet (1999)

In 1997, I photographed the US Senior Olympics in Tucson, Arizona. Taking part were people aged 55 to more than 100 years. My favourite athlete was this 82-year-old swimmer with a pacemaker proudly protruding from his chest. I decided that anyone good enough to make it to this competition must have been swimming in competitions his whole life. Not true. This man had started swimming only after his heart surgery, when his doctor told him either to pick a sport or to get his affairs in order. So he had started swimming with his buddies and quickly discovered he was a very good swimmer.
Questions and Answers
Journal: JAMA (1984)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Poisoning Young Minds
Authors: Charles W. Schmidt
Journal: Environmental Health Perspectives (1999)

For some neurotoxic chemicals, neurobehavioral effects are now considered to be among the most sensitive end points yet detected, particularly if exposures occur during critical windows of vulnerability. Chemically induced problems with perception and cognitive ability in children can be hard to identify; teasing them out of a host of genetic and sociocultural influences is a difficult task. Today, most data on environmentally relevant neurobehavioral effects in children are concentrated in three chemicals: lead, methylmercury, and polychlorinated biphenyls. But mounting evidence of the neurobehavioral effects of chemicals along with growing public concern over pediatric mental health problems such as attention deficit/hyperactivity disorder dictates that scientists and legislators improve test methods, explore mechanisms, and develop appropriate strategies for risk assessment and policy making.
Mental Health in the United States: Prevalence of Diagnosis and Medication Treatment for Attention-Deficit/Hyperactivity Disorder—United States, 2003
Journal: JAMA (2005)

Attention-deficit/hyperactivity disorder (ADHD), previously known as attention deficit disorder, is a neurobehavioral disorder characterized by pervasive inattention and hyperactivity-impulsivity that often results in substantial functional impairment. Prevalence estimates of ADHD in school-aged children have ranged from 2% to 18% in community samples. Although stimulant medications are an effective first-line treatment for ADHD , concern persists regarding the possible side effects and long-term health outcomes associated with stimulant consumption. Estimating the number of children who have had ADHD diagnosed and are currently taking medication for the disorder is an important step toward understanding the overall burden of ADHD in the United States. Previously, population-based estimates of medication treatment for ADHD were not available or were limited by their lack of generalizability. To estimate rates of parent-reported ADHD diagnosis and medication treatment for ADHD, CDC analyzed data from the 2003 National Survey of Children's Health (NSCH). This report describes the results of that analysis, which indicated that, in 2003, approximately 4.4 million children aged 4-17 years were reported to have a history of ADHD diagnosis; of these, 2.5 million (56%) were reported to be taking medication for the disorder. Because both substantial health risks and benefits might be associated with medication treatment for ADHD, further study of this population of children with ADHD is needed.
Ship Owners and Marine Hospital Service.
Journal: JAMA (1884)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Seeking Aesculapius
Authors: Phillip S. Pang
Journal: JAMA (1997)

There is a god we applicants to medical school prayed to, because catching a dream is not an easy thing. We prayed because we one day hope to possess the power and reverence of Aesculapius, and power and reverence are not without cost. We prayed in hopes of easing our journey, for a well-marked path and a guide to lead us, without fully comprehending how large the toll would be. For the god that we prayed to was composed of all the myths, fears, and sad truths that permeate the medical school application process, and it guided us in darkness. Too willingly we allowed this dark god to lead us, never fully recognizing the extent of our debasement. All we saw or felt was a savior who possessed the secrets of the admissions process. We rhetorically asked ourselves, "What do we have to lose?" as we knelt before this god
JAMA, India
Authors: Irving Thomas
Journal: JAMA (1987)

Recognizing a need for physicians continuously to stay abreast of medical research, and encouraged by concerned ministries of the Indian government, Dr J. K. Jain, in April 1987, launched<i>JAMA, India</i>. Dr Jain, the editor and publisher of this new journal, is involved in many projects dealing with organized medicine and medical education. He is former president of the New Delhi branch of the Indian Medical Association, and most recently he has been the principal force behind Medical Television, the first project of its kind in India, providing video films on medicine, health, and family planning for both national television and professional institutions. The editorial board of<i>JAMA, India</i>includes Dr G. K. Vishvakarma, director, General Health Services, government of India; Dr A. K. N. Sinha, president, Medical Council of India; and Col M. L. Sapra, VSM, directorate general, Armed Forces Medical Services. Other facets of organized medicine are represented
Asbestos Affects the in Vitro Uptake and Detoxification of Aromatic Compounds
Authors: R. C. Brown, G. T. A. Fleming, A. I. Knight
Journal: Environmental Health Perspectives (1983)

A number of mineral dusts were tested for their ability to catalyze the transformation of benzo(a)pyrene from the microcrystalline state into lipid solution. The findings of Lakowicz and his co-workers, that fibrous dusts were more active than nonfibrous dusts, were confirmed. Macromolecular binding metabolites of BaP were formed in A549 cells to a similar extent whether the BaP was added in solution or adsorbed to fibers; however, the level of water-soluble metabolites was lower in cultures treated with adsorbed hydrocarbon. It was found that asbestos can also inhibit the accumulation of 1-naphthyl glucuronide in cultures treated with 1-naphthol. The significance of this in asbestos pathogenesis is briefly discussed.
SOMATIC COPY NUMBER GAINS IN MYC, BCL2, OR BCL6, IN ADDITION TO TRANSLOCATIONS, IDENTIFIES A SUBSET OF AGGRESSIVE ALTERNATIVE-DH/TH DLBCL PATIENTS
Authors: J. Krull, K. Wenzl, K. Hartert, M. Manske, V. Sarangi, P. Greipp, M. Maurer, M. Larson, S. Ansell, E. McPhail, T. Habermann, R. King, J. Cerhan, A. Novak
Journal: HemaSphere (2019)
Work stress and risk of cardiovascular mortality: prospective cohort study of industrial employees
Journal: BMJ (2002)

Objective To examine the association between work stress, according to the job strain model and the effort-reward imbalance model, and the risk of death from cardiovascular disease.Design Prospective cohort study.Baseline examination in 1973 determined cases of cardiovascular disease, behavioural and biological risks, and stressful characteristics of work.Biological risks were measured at 5 year and 10 year follow up.Setting Staff of a company in the metal industry in Finland.Participants 812 employees (545 men, 267 women) who were free from cardiovascular diseases at baseline.Main outcome measure Cardiovascular mortality 1973-2001 from the national mortality register.Results Mean length of follow up was 25.6 years.After adjustment for age and sex, employees with high job strain, a combination of high demands at work and low job control, had a 2.2-fold (95% confidence interval 1.2 to 4.2) cardiovascular mortality risk compared with their colleagues with low job strain.The corresponding risk ratio for employees with effort-reward imbalance (low salary, lack of social approval, and few career opportunities relative to efforts required at work) was 2.4 (1.3 to 4.4).These ratios remained significant after additional adjustment for occupational group and biological and behavioural risks at baseline.High job strain was associated with increased serum total cholesterol at the 5 year follow up.Effort-reward imbalance predicted increased body mass index at the 10 year follow up.Conclusions High job strain and effort-reward imbalance seem to increase the risk of cardiovascular mortality.The evidence from industrial employees suggests that attention should be paid to the prevention of work stress.
Screening for Colorectal Cancer: The Accuracy of Fecal Occult Blood-Reply
Authors: David A. Ahlquist
Journal: JAMA (1993)

<h3>In Reply.</h3> —Dr Greegor speculates that our colorectal cancers were young and, accordingly, that detection rates were very good. Many primary cancers in the postresection group may have been synchronous rather than metachronous, as they were discovered at the first colorectal follow-up evaluation and were large in size. Nevertheless, premalignant adenomas or early-stage cancers, rather than late-stage cancers, are the important targets for screening. The observed miss rates of about 70% for cancer and 90% for polyps will certainly compromise the efficacy of screening or case detection. We are unaware of data on how a high-roughage diet affects FOBT validity. As we stated in the "Methods" section, HemoQuant results were expressed as hemoglobin equivalents for the very reasons given by Drs Young and St. John. The various classes of FOBTs detect different components or analytes of hemoglobin, and none measures the molecule in total. Because its analytes include both intact
Certification in Diagnostic Laboratory Immunology
Authors: REBECCA H. BUCKLEY
Journal: Annals of Internal Medicine (1986)

Editorials1 March 1986Certification in Diagnostic Laboratory ImmunologyREBECCA H. BUCKLEY, M.D., Sheldon M. Wolff, M.D., Robert E. Reisman, M.D., Max D. Cooper, M.D.REBECCA H. BUCKLEY, M.D.Search for more papers by this author, Sheldon M. Wolff, M.D.Search for more papers by this author, Robert E. Reisman, M.D.Search for more papers by this author, Max D. Cooper, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-104-3-435 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe first examination for certification of special qualification in diagnostic laboratory immunology will be held 10 October 1986 in St. Louis. The examination was announced in last month's Medical Notices section, and a second notice appears in this issue. The examination, which will assess the competence of internists and pediatricians conducting diagnostic immunologic tests, is analogous to the special qualifications examination in immunopathology of the American Board of Pathology. It is open to physicians certified by the American Board of Internal Medicine, the American Board of Pediatrics, or the American Board of Allergy and Immunology who also have training, or... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: REBECCA H. BUCKLEY, M.D.; Sheldon M. Wolff, M.D.; Robert E. Reisman, M.D.; Max D. Cooper, M.D. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 March 1986Volume 104, Issue 3Page: 435-435KeywordsAllergy and immunologyImmunologyImmunopathologyPediatricsResearch laboratories ePublished: 1 December 2008 Issue Published: 1 March 1986 PDF downloadLoading ...