tbuckley/cabot-search huggingface dataset:
The Pulse Monitor
Authors: Constantin Cope
Journal: JAMA (1967)

THE DEVELOPMENT of simple percutaneous arteriographic catheterization techniques, the synthesis of safer contrast media, the ready availability of good angiographic roentgenographic equipment, and the increasingly large number of surgeons with training in vascular surgery have created a situation in which most large hospitals are now expected to have an efficient angiographic department. There has been a resultant marked increase in the utilization of arteriographic procedures throughout the country despite the fact that at present relatively few physicians are thoroughly grounded in all aspects of angiography. Recent large reviews of catheter aortographic procedures<sup>1-4,5</sup>showed that, while mortality was very low, there was a significant number of serious nonfatal complications at the site of catheter insertion, such as massive hematomas, uncontrolled bleeding, arterial thromboses, and subintimal dissections, some of which led to permanent disability. The incidence of major arterial thrombosis is usually less than 1% but can be as high as
Colchicine in acute gout. Reassessment of risks and benefits
Authors: W. N. Roberts
Journal: JAMA (1987)

Colchicine is an effective and relatively specific treatment for acute gout and has a long, venerable history. Serious toxic reactions to colchicine could be prevented if guidelines for its use were followed strictly, but because of its relatively infrequent use and conflicting recommendations, considerable toxic effects might occur and still be undetected by passive surveillance. A review of a teaching hospital's four years' experience showed two deaths (2% incidence) due to inappropriate use. Colchicine has the smallest benefit-to-toxicity ratio of drugs that are effective for acute gout. This article gives specific recommendations for the use of colchicine in different clinical settings. (<i>JAMA</i>1987;257:1920-1922)
Ward Design in Relation to Postoperative Wound Infection: Part III
Authors: G. Smith, J. R. C. Logie, A. Macdonald, H. G. Smylie
Journal: BMJ (1974)

The wound infection rates, nasal carriage rates, and nasal colonization rates were studied in a recently built surgical unit for two years when it was first opened. Five years later a further two-year period of study was undertaken. Judging by the incidence of postoperative wound infection, as far as both Staphylococcus pyogenes and Gram-negative organisms are concerned, there is no evidence that the environment has become less safe with use over the seven-year period since opening.
Obituary Listing
Journal: JAMA (1997)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Autoantibody against dihydrolipoamide dehydrogenase, the E3 subunit of the 2-oxoacid dehydrogenase complexes: Significance for primary biliary cirrhosis
Authors: T Maeda
Journal: Hepatology (1991)

Autoantibodies in primary biliary cirrhosis recognize mitochondrial 2-oxacid dehydrogenase complexes, particularly the E2 subunits. Reactivity with the E3 subunit, common to each of the enzyme complexes, was sought by immunoblotting, with sera screened at 1:100 instead of the conventional 1:1,000 dilution. This was found in 11 of 29 sera from patients with primary biliary cirrhosis but also in 10 of 40 sera from normal subjects. Two-dimensional immunoblotting and immunoblotting on purified enzymes established that the reactivity was actually with E3 rather than with another component of the 2-oxoacid enzymes of similar molecular weight. Purified antibodies to E3 eluted from an affinity column did not cross-react with other components of the 2-oxoacid enzyme complexes. The antibodies to E3 did not react with the Escherichia coli or yeast E3 subunits, suggesting that they are not stimulated by immune responses against microorganisms. Thus the proposal that reactivity to the shared E3 subunit of the 2-oxoacid enzyme complexes could initiate primary biliary cirrhosis is not reflected at the antibody level. (HEPATOLOGY 1991;14:994–999.)
Finding our way on a path to the future
Authors: C. L. Hudson
Journal: JAMA (1966)

It is with the deepest gratitude that I accept the high honor which you have entrusted to me. I am proud to be privileged to put on the mantle of leadership, worn in the past by so many distinguished physicians. I look forward to meeting the responsibilities and challenges that devolve upon all of us at this, for us, dramatic time in the history of medicine. I shall carry the title of President of this Association with understandable pleasure for the next year, and to the best of my ability shall discharge the obligations and responsibilities inherent in this honored position. Yet, I am not so naïve—or so presumptuous— as to believe that the future of medicine in America lies exclusively in my hands, nor that it lies entirely in those of other officers, or of members of boards and councils and of delegates to the legally constituted legislatures of
ADDRESS.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Transactions of the Medical and Chirurgical Faculty of the State of Maryland.
Journal: JAMA (1893)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
1969 Medical Disciplinary Report
Journal: JAMA (1970)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abdominal Operations.
Journal: JAMA (1926)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Degradation of bile salts by human intestinal bacteria.
Authors: V Aries, J S Crowther, B S Drasar, M J Hill
Journal: Gut (1969)

We have previously reported that many strains of enterococci and the strictly anaerobic bacteria of the intestine (Bacteroides, Bifidobacteria, Clostridia, and Veillonella) hydrolyse bile acid conjugates (Drasar, Hill, and Shiner, 1966; Hill and Drasar, 1968).More detailed studies on the deconjugating enzyme, cholanylglycine hydrolase, obtained from Bacteroides spp, Bifidobacterium spp, Clostridium spp, and Strep.faecalis (two strains of each) are reported elsewhere (Aries and Hill, 1969).Here we report our studies on the metabolism of cholate and deoxycholate, and further studies on deconjugation.
Structural Information in Diffuse Diffraction Patterns
Authors: J. H. Konnert
Journal: Environmental Health Perspectives (1974)

The radiation diffraction pattern for amorphous materials requires special analysis for information on atomic groupings. Powdered crystalline material may also give diffuse patterns requiring this type of analysis. Absence of a sharp diffraction pattern does not necessarily indicate absence of the material. Examples are given for chrysotile and powdered chrysotile.
Ten years of the Global Alliance for Vaccines and Immunisation
Journal: BMJ (2010)

Successes of immunisation are tempered by slow progress in strengthening health systemsThe Global Alliance for Vaccines and Immunisation (GAVI), now known as the GAVI Alliance, was created in 2000 to increase the availability and use of immunisation in poor countries.GAVI's launch, which was made possible by a startup grant of $750m (£486m; €550m) from the Gates Foundation, was part of broader efforts by world leaders to strengthen public health action across the globe in the late 1990s.Nine million children die in the developing world annually, two million from diseases for which vaccines are available.Over the past decade, GAVI has immunised 256 million children and, in doing so, has averted five million deaths.1
Bacteria in Condiment Sauces on Tables in Mexican-Style Restaurants in Guadalajara, Mexico, and Houston, Texas
Journal: Annals of Internal Medicine (2002)

Summaries for Patients18 June 2002Bacteria in Condiment Sauces on Tables in Mexican-Style Restaurants in Guadalajara, Mexico, and Houston, TexasSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-136-12-200206180-00005 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail What is the problem and what is known about it so far?Traveler's diarrhea results when travelers eat or drink food or water that is contaminated with certain types of bacteria. These bacteria (bacterial enteropathogens) commonly cause traveler's diarrhea among tourists in Mexico. Although Escherichia coli (E. coli) is normally present in the intestines of humans, certain types of E. coli cause traveler's diarrhea. Information about the types of foods that become contaminated with E. coli can help travelers reduce their risk for diarrhea.Why did the researchers do this particular study?To see whether Mexican-style sauces kept on restaurant ... Author, Article, and Disclosure InformationAffiliations: The summary below is from the full report titled “Enteric Pathogens in Mexican Sauces of Popular Restaurants in Guadalajara, Mexico, and Houston, Texas.” It is in the 18 June 2002 issue of Annals of Internal Medicine (volume 136, pages 884-887). The authors are JA Adachi, JJ Mathewson, Z-D Jiang, CD Ericsson, and HL DuPont.Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. The summaries may be reproduced for not-for-profit educational purposes only. Any other uses must be approved by the American College of Physicians-American Society of Internal Medicine. Previousarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoEnteric Pathogens in Mexican Sauces of Popular Restaurants in Guadalajara, Mexico, and Houston, Texas Javier A. Adachi , John J. Mathewson , Zhi-Dong Jiang , Charles D. Ericsson , and Herbert L. DuPont Metrics 18 June 2002Volume 136, Issue 12Page: I-56KeywordsBacteriaDiarrheaEatingEscherichia coliFoodPathogens ePublished: 18 June 2002 Issue Published: 18 June 2002 Copyright & PermissionsCopyright © 2002 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
A case-control study of caffeine and methylxanthines in benign breast disease
Authors: F. Lubin
Journal: JAMA (1985)

A dietary case-control study of 854 histologically diagnosed cases of benign breast disease (BBD), 755 matched surgical controls, and 723 matched neighborhood controls was conducted in Israel between 1977 and 1980. No association between coffee consumption and BBD was found. Analyses by histological type, degree of ductal atypia, age, sex, and ethnic origin, controlling for several confounding factors, confirmed the lack of association. The estimated mean intake of methylxanthines was also similar for cases and controls (302, 312, and 313 mg for cases, surgical controls, and neighborhood controls, respectively). No evidence of a dose-response was noted. Our results suggest that there is no association between coffee or methylxanthine consumption and BBD, although we had a 70% chance of finding a risk ratio of 1.5 with an error of 5%. (<i>JAMA</i>1985;253:2388-2392)
Greater use of fibrinolytic agents urged
Authors: J. Elliott
Journal: JAMA (1980)

The thrombolytic agents urokinase and streptokinase are safe and more effective than traditional anticoagulants in treating deep-vein thrombosis and pulmonary embolism in carefully selected patients, a panel of experts convened by the National Institutes of Health (NIH) has concluded. In an official statement following a two-day NIH consensus development conference on fibrinolytic therapy held earlier this spring, the panel members agreed that the risk of uncontrolled bleeding that has been associated with the two drugs is actually far less than was indicated by the original clinical trials. In addition, the long-term benefits of streptokinase and urokinase make them far superior to heparin sodium in most cases. In urging that the two drugs be used more often, the consensus panel, headed by Sol Sherry, MD, chairman of the Department of Medicine at Temple University School of Medicine, Philadelphia, was attempting to overcome a marked hesitance on the part of clinicians to
Interest heightens in defining, preventing AIDS in high-risk adolescent population
Authors: J. W. Zylke
Journal: JAMA (1989)

ALTHOUGH the acquired immunodeficiency syndrome (AIDS) epidemic has been developing for years, the main focus has been on adults with the disease and secondarily on children. Until the last year or two, little attention has been paid to adolescents. This may seem reasonable if one considers that just 1% of reported AIDS cases occur in those 13 to 21 years old. However, an increasing number of cases, the realization that most young adults were infected during adolescence, and the recognition that certain behavioral and psychological factors put adolescents at high risk have increased interest in defining and preventing the disease in this age group. Some attention was drawn to this problem at the Fourth International Conference on AIDS held in Stockholm, Sweden (<i>JAMA</i>. 1988;260:757-758). During the last year, additional information has been gathered, but much remains to be learned, and even more remains to be done to contain the epidemic
Misleading corticotropin levels in Cushing's disease
Authors: R. W. Newton
Journal: JAMA (1978)

PATIENTS with ectopic adrenocorticotropic hormone (ACTH) production frequently do not show all the typical clinical features of Cushing's syndrome despite high plasma ACTH and cortisol levels.<sup>1</sup>Classically, severe hypokalemic alkalosis and hyperglycemia occur. Occasionally a cushingoid appearance may develop in association with low-grade malignant and benign tumors such as carcinoid tumors of the lung.<sup>2</sup> In our patient ectopic ACTH production was suspected despite a grossly cushingoid appearance because of exceedingly high plasma ACTH and cortisol levels. The subsequent clinical course, however, led to the diagnosis of Cushing's disease because of excess pituitary ACTH secretion exhibiting periodicity of hormone production. We report the case because of the unusual presentation and the misleading levels of plasma ACTH and cortisol. <h3>Report of a Case</h3> A 55-year-old woman who smoked but had no past history of chest disease was admitted to hospital with pneumonia. Consolidation of the right upper lobe was confirmed
The Milroy Lectures ON THE INFLUENCE OF INDUSTRIAL EMPLOYMENT UPON GENERAL HEALTH: Delivered before the Royal College of Physicians of London on March 9th, 14th, and 16th, 1922
Authors: None Greenwood
Journal: BMJ (1922)

WITHIN the thirty-six years which have passed since the death of Dr. Gavin Milroy many aspects of State medicine lhave been examined by those to whom the College has accorded the lhonour of lecturing upon his foundation.Some -for instance, Dr. Boycott in Iiis lectures on ankylostomiasis (1911), or Dr. Collis in his account of the etiology of industrial.pneumonoconioses (1915)-hlave lhad the privilege of describing evils to the amelioration 6f wlhich their own researclles were substantial contributions.Others-such as the late Dr. Bulstrode (1903) and Dr. Hamer (1906)-lhave brought ripe experience and wide erudition to bear upon more general and still unsolved problems.The theme I have chosen-tlje direct and indirect influence of industrial employment upon health-involves the con- sideration of botlh solved and unsolved problems.I am conscious that neither by virtue of having contributed to tlle solution of the former, nor by intimate knowledge of tile difficulties of the latter, am I well fitted to throw light upon so important a topic.But the topic is so important, the data are so numerous and so interesting, that the least competent lec'urer can lhardly fail to advance some propositions worthy of attention.ANCIENT INDUSTRY.Factory production, as we understan,d the term, is so novel, it is so slhort a time (measured in human generations) since our country was a self-contained agricultural state, that modern induistrial medicine has but few traditions.To the founider of this College a description of twentieth-century m-nedico- industrial problems would appear as monstrous, as grote3que, as tlle story of economic conditions in the nineteenthl century seemed to John Ball in Morris's tale.We must pass back to the Roman civilization before we find anytlhing even faintly analogous to our own times.Then we do reach a great
Maternal brain death during pregnancy. Medical and ethical issues
Authors: D. R. Field
Journal: JAMA (1988)

We present in detail a case of a 27-year-old primigravida who was maintained in a brain-dead state for nine weeks. An apparently normal and healthy male infant weighing 1440 g was delivered. The newborn did well and was found to be growing and developing normally at 18 months of age. Although the technical aspects of prolonged life support are demanding and the economic costs are very high ($217 784), there are ample ethical arguments justifying the separation of brain death and somatic death and the maintenance of the brain-dead mother so that her unborn fetus can develop and mature. (<i>JAMA</i>1988;260:816-822)
Atypical Leukemia
Authors: Thomas R. Blair
Journal: JAMA (1966)

Sixteen patients had atypical leukemia but the original bone-marrow specimens and blood smears were not diagnostic of leukemia. Thirteen were men, and all 16 were more than 50 years old. Clinical features were nonspecific in most cases. Initial manifestations that might have served as clues to a leukemic process were (1) monocytosis in the peripheral blood, (2) normoblasts in the peripheral blood in the presence of cytopenia, (3) marrow hypercellularity, frequently with hyperplastic or left-shifted myelopoiesis, (4) erythroid hyperplasia of the marrow, often with qualitative erythroid changes, and (5) acquired Pelger-Huët anomaly or changes in the granulation of myeloid cells. Survival time from onset of a known hematologic abnormality ranged from seven to 60 months, with only two patients surviving less than one year.