tbuckley/cabot-search huggingface dataset:
Motility
Authors: J Konturek, M Maczka, P Thor, A Gabryelewicz, R Stoll, W Domschke
Journal: Gut (1994)

3rd UEGWOslo 1994 by direct sequencing showing a normal Ki-ras 12th codon.In group 2, 11/14 patients with pancreatic carcinoma, 2/2 cystadenocarcinoma, 2/3 ampullary tumors, 1/3 cholangiocarcinoma, and 0/3 islet cell tumors showed punctual mutation of Ki-ras.In group 3, 4/18 showed a mutation of Ki-ras at the 12th codon.Conclusion: Endoscopic retrograde intraductal catheter aspiration is a simple technique to analyse cell samples.Specificity of PCR mediated RFLP was 94.5, and sensitivity for pancreatic carcinoma was 81 %.Identification of Ki-ras mutation could distinguish pancreatic carcinoma from islet cell tumors, but not from other tumors.Clinical follow-up patients from group 3 will found out the real value of this early diagnostic test.
Silicosis Deaths Among Young Adults—United States, 1968-1994
Journal: JAMA (1998)

Silicosis is a potentially fatal and typically chronic fibrotic lung disease caused by occupational exposure to respirable crystalline silica dust. In the United States, most silicosis-associated deaths occur among persons aged > or = 65 years, often following many years of silica dust exposure. However, the continuing occurrence of silicosis deaths in young adults reflects relatively recent overexposures, some of sufficient magnitude to cause severe disease and death after relatively short periods of exposure. This report describes deaths among two young adults with silicosis and underscores the risk for deaths from silicosis at relatively young ages.
Risk Assessment of Environmentally Influenced Airway Diseases Based on Time-Series Analysis
Authors: Olf Herbarth
Journal: Environmental Health Perspectives (1995)

Threshold values are of prime importance in providing a sound basis for public health decisions. A key issue is determining threshold or maximum exposure values for pollutants and assessing their potential health risks. Environmental epidemiology could be instrumental in assessing these levels, especially since the assessment of ambient exposures involves relatively low concentrations of pollutants. This paper presents a statistical method that allows the determination of threshold values as well as the assessment of the associated risk using a retrospective, longitudinal study design with a prospective follow-up. Morbidity data were analyzed using the Fourier method, a time-series analysis that is based on the assumption of a high temporal resolution of the data. This method eliminates time-dependent responses like temporal inhomogeneity and pseudocorrelation. The frequency of calls for respiratory distress conditions to the regional Mobile Medical Emergency Service (MMES) in the city of Leipzig were investigated. The entire population of Leipzig served as a pool for data collection. In addition to the collection of morbidity data, air pollution measurements were taken every 30 min for the entire study period using sulfur dioxide as the regional indicator variable. This approach allowed the calculation of a dose-response curve for respiratory diseases and air pollution indices in children and adults. Significantly higher morbidities were observed above a 24-hr mean value of 0.6 mg SO2/m3 air for children and 0.8 mg SO2/m3 for adults.(ABSTRACT TRUNCATED AT 250 WORDS)
Recovery From Major Depression in Older Adults Receiving Augmentation of Antidepressant Pharmacotherapy
Authors: Mary Dew
Journal: American Journal of Psychiatry (2007)

Objective: Few data are available concerning the utility of augmentation in late-life depression treatment. The authors examined likelihood, speed, and predictors of recovery in older adults receiving augmentation pharmacotherapy after inadequate response to standardized treatment with paroxetine plus interpersonal psychotherapy. Method: Depression levels were monitored during open treatment in 195 adults age 70 or older. Patients were grouped by whether they required augmentation (bupropion, nortriptyline, or lithium) and compared on likelihood, time, and predictors of recovery. Results: Augmentation was required for 105 patients (53.8%) because of inadequate treatment response (N=77) or response followed by relapse (N=28). Of these patients, 69 received augmentation and 36 did not (primarily because of consent withdrawal or comorbid medical conditions). Patients receiving augmentation showed lower recovery rates than patients never requiring augmentation: recovery occurred in 50.0% of patients receiving it because of inadequate response, 66.7% of those receiving it after early relapse, and 86.7% of patients never requiring augmentation. Patients receiving augmentation because of inadequate response recovered more slowly, with modestly more side effects than other patients. Greater medical burden and anxiety predicted slower recovery. Conclusions: Despite a lower likelihood of recovery in elderly people receiving augmentation, the recovery by over one-half of such patients suggests the value of augmentation for those able to tolerate it. Need for augmentation presages slower recovery in patients showing initial inadequate response; those requiring it after early relapse recovered more quickly. Strategies to further improve the likelihood and speed of recovery after initial treatment failure are needed.
Childish Habit
Journal: JAMA (2014)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
"Umbilical Hemorrhage Accompanied by Deep Jaundice."
Journal: JAMA (1926)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
BOOK REVIEWS
Authors: P. M. SONDEL
Journal: JNCI Journal of the National Cancer Institute (1992)

Journal Article BOOK REVIEWS Get access 2nd Review of Biologic Therapy of Cancer PAUL M. SONDEL, M.D.,Ph.D. PAUL M. SONDEL, M.D.,Ph.D. Dept. of Pediatrics, Dept. of Human Oncology and Genetics University of Wisconsin Clinical Science Center600 Highland Ave. Madison, WI 53792-0001 Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 84, Issue 19, 7 October 1992, Page 1528, https://doi.org/10.1093/jnci/84.19.1528 Published: 07 October 1992
Journal Loses Ihde to Washington University, Names NCI's Kramer as New Chief
Journal: JNCI Journal of the National Cancer Institute (1994)

Journal Article Journal Loses Ihde to Washington University, Names NCI's Kramer as New Chief Get access JNCI: Journal of the National Cancer Institute, Volume 86, Issue 3, 2 February 1994, Page 176, https://doi.org/10.1093/jnci/86.3.176 Published: 02 February 1994
Bacteriologia
Journal: JAMA (1934)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Periodic Health Examination— How Effective?
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Estrogen Replacement Therapy in Breast Cancer Survivors
Authors: Carl D. Atkins
Journal: JAMA (1995)

<h3>To the Editor.</h3> —Dr Cobleigh and colleagues<sup>1</sup>state that the 27 studies they analyzed "do not consistently demonstrate an increased risk of breast cancer among women who have ever used ERT [estrogen replacement therapy]." However, they fail to recognize that most "negative" studies do not have sufficient power to rule out clinically significant differences (see confidence intervals in Table 1 of Cobleigh et al). Since the most reliable estimates of association of any factor with a disease are obtained from prospective cohort studies rather than retrospective case-control studies, it is important that a prospective analysis based on the Nurses' Health Study<sup>2</sup>showed a moderate increase in the risk of breast cancer associated with current use of ERT. Bergkvist et al<sup>3</sup>also found an increased risk of breast cancer in their prospective study from Sweden, which, in addition, showed no protection from the addition of progestins. Cobleigh et
Chronic pneumococcal infection complicating progressive lymphoma
Authors: M. Markman
Journal: JAMA (1983)

<h3>In Reply.—</h3> The data in our article demonstrated a small increase in plasma alcohol levels when patients received cimetidine concurrently with alcohol. Although the mechanism responsible for these changes is unclear, the various possibilities, including increased absorption, were fully discussed in our article. It seems that Dr Tan and colleagues have data that show an increased peak plasma alcohol concentration after cimetidine administration, compatible with our findings, but no notable change in the rate of alcohol absorption. It is unclear, therefore, why they think that increased gastric motility is responsible for the increased alcohol concentrations with cimetidine seen in our study not only at peak levels but for eight hours after administration. The only published reference cited by Dr Tan and colleagues<sup>1</sup>in support of their claim is a letter published by themselves that measured skin oxygen tension on the face after alcohol consumption with and without H<sub>1</sub>and
Surveillance for Creutzfeldt-Jakob Disease—United States
Journal: JAMA (1996)

Creutzfeldt-Jakob disease (CJD) in humans and bovine spongiform encephalopathy (BSE) in cattle are subacute degenerative diseases of the brain classified as transmissible spongiform encephalopathies. BSE was first identified in 1986 in the United Kingdom (UK), where an epizootic involving > 155,000 cattle appeared to have been greatly amplified by exposure of calves to contaminated rendered cattle carcasses in the form of meat and bone meal nutritional supplements. On March 20, 1996, and expert advisory committee to the government of the UK (1995 estimated population: 58.3 million) announced its conclusion that the agent responsible for BSE might have spread to humans, based on recognition of 10 persons with onset of a reportedly new variant form of CJD during February 1994-October 1995. The 10 persons ranged in age from 16 to 39 years (median age at illness onset: 28 years); of the eight persons who had died, five were aged <30 years. In comparison, in the United States, deaths associated with CJD among persons aged <30 years have been extremely rare (median age at death: 68 years). As a result of the newly recognized variant of CJD described in the UK, CDC updated its previous review of national CJD mortality and began conducting active CJD surveillance in five sites in the United States. These reviews did not detect evidence of the occurrence of the newly described variant form of CJD in the United States.
Is it obvious why patients ask questions?
Authors: J. R. Glaser
Journal: JAMA (1976)

THE QUESTIONS that patients put to their physicians are more than unilevel in meaning. On the one hand, they deal with the reality factors of being ill; on the other, they involve root problems of dependency, potency, shame, guilt, and self-awareness. The question "Why did all this happen to me?" reiterated from the book of Job is often dismissed as a philosophical or theological dilemma. Nothing human is outside the scope of medicine. An analysis and attempt to answer this question is a useful introduction to the human process of becoming ill. Complementary to the molecular disturbances involved in illness and aging, a similar homologous disruption is occurring at a psychological level. Stable psychic structures are called into question. Previous self-images are no longer coherent and consistent. Job was a righteous man and offered sacrifice daily to God, but still he lost his possessions and became ill with a skin
Fourth-order blood pressure waves
Authors: G. C. Carroll
Journal: JAMA (1990)

A critically ill 80-year-old man had blood pressure waves with a period of about 30 minutes. These blood pressure oscillations, lasting longer than 18 hours, were accompanied by oscillations in heart rate, central venous pressure, pulmonary arterial pressure, and oxygen saturation of mixed venous blood. No discernible variations in external conditions caused the oscillations. Oscillations with such long periods heretofore have not been reported. (<i>JAMA</i>. 1990;263:856-857)
Abstract 5799: Fine-Cell Detector Computed Tomography with 0.3mm-Collimation Improves Quantitative Assessment of Coronary Artery Stenosis: Experimental Study with Coronary Phantom
Authors: Minoru yamada, Masahiro Jinzaki, Kozo Sato, Yutaka Tanami, Akihisa Ueno, Yasuhiro Imai, Masatake Nukui, Yotaro Ishihara, Kosuke Sasaki, Sachio Kuribayashi
Journal: Circulation (2008)

The purpose of this study was to evaluate whether the prototype fine-cell detector computed tomography (FDCT) could improve smaller coronary artery stenosis measurement compared with 64-slice multidetector-row CT (MDCT). Method and Materials: We developed coronary phantoms of 2mm in diameter with 0%, 25%, 50%, 75% stenosis. Each stenotic part was made by Acrylonitrile-Butadiene-Styrene (ABS: 50 Hounsfield Unit (HU)) and lumen was filled with diluted iodine (380 HU). These coronary phantoms put into the water tank were scanned by both prototype FDCT and 64-slice MDCT. Configuration of FDCT was 32-row*0.3125mm detector collimation with 0.35mm smaller X-ray tube focal spot width, and that of 64-slice MDCT was 16-row*0.625mm detector collimation and 0.7mm X-ray focal spot. All axial images were reconstructed using Standard kernel with 96mm display field-of-view. Minimum lumen diameter and degree of stenosis in these data sets were automatically measured using the Vessel Analysis software (GE Healthcare). Results: Measured coronary lumen at 0%, 25%, 50%, 75% stenosis of 2mm-diameter phantom (corresponding to 2.0mm, 1.5mm, 1.0mm, 0.5mm) were 2.2mm, 1.8mm, 1.4mm, 0.7mm in FDCT, whereas those were 2.5mm, 2.0mm, 1.5mm, 1.4mm in 64-slice MDCT, respectively. Each degree of stenosis was calculated 21%, 38%, 69% in FDCT, while 20%, 38%, 44% in 64-slice MDCT. Measured value of 75% stenosis in FDCT was significantly improved compared with 64-slice MDCT. Conclusion: FDCT improves the accuracy of smaller coronary artery stenosis measurement compared with 64-slice MDCT. Superior spatial resolution of FDCT could be promising for more accurate assessment of the coronary artery stenosis.
Sign Language
Authors: Emma Woody
Journal: JAMA (1965)

<h3>To the Editor:—</h3> In the Sept 13 issue ofThe Journal(adv p 33), Dr. Chen is described as having developed a special hand alphabet with which stroke patients can communicate using their left hands. A hand alphabet is already known and used by many deaf mutes and their friends, which probably was a combination of an alphabet developed by a Spanish monk, Pedro Ponce de Leon and by Abbé (Charles Michel) de L'Epée in the 1580's. The Reverend Gallaudet, after studying in France, introduced the sign language in America in the 1820's. Two recent books on hand signals are listed below.<sup>1,2</sup> This widely-used sign language contains individual letters as well as all the common words that might be used by a stroke victim. In review of the hand signals suggested by Dr. Chen, it is noted that 8 signs resemble accepted alphabet hand signs (C, H, K, L,
Tumor Promoters in Commercial Indoor-Plant Cultivars of the Euphorbiaceae
Authors: Gerd Vogg, Elke Mattes, Axel Polack, Heinrich Sandermann
Journal: Environmental Health Perspectives (1999)

Certain decorative indoor-plant cultivars are derived from toxic wild plant species. Native members of the Euphorbiaceae (spurge) contain highly irritating and tumor-promoting diterpene esters. Plant breeders and gardeners are constantly searching for less toxic cultivars of the popular Euphorbiaceae indoor plants. In this investigation, 22 commercial cultivars of Euphorbiaceae indoor plants were examined for tumor promoter contents by high-performance liquid chromatography (HPLC). Cultivars of E. milii (E. lomii hybrids), and in particular E. leuconeura, contained ingenol derivatives, whereas cultivars of E. pulcherrima and Codiaeum variegatum were devoid of these compounds. Tumor-promoting activity was assessed by induction of a luciferase reporter gene, which was placed under the control of an Epstein-Barr virus early antigen promoter. The response was closely correlated with ingenol ester content; the latex of the two E. leuconeura cultivars tested gave the strongest response. The HPLC and bioassay methods used in this study provide a basis for the development of nontoxic indoor-plant cultivars and perhaps for consumer-oriented labeling.
"EAR TESTS FOR AVIATORS"
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal