tbuckley/cabot-search huggingface dataset:
Deescalation
Authors: Stanley Cohen
Journal: Annals of Internal Medicine (2016)

Ad Libitum5 January 2016DeescalationStanley Cohen, MDStanley Cohen, MDFrom Atlanta, Georgia.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/M15-2106 Audio Reading - “Deescalation” Audio. Michael A. LaCombe, MD, Annals Associate Editor, reads "Deescalation," by S. Cohen. Your browser does not support the audio element. Audio player progress bar Step backward in current audio track Play current audio trackPause current audio track Step forward in current audio track Mute current audio trackUnmute current audio track 00:00/ SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail What do you do when you come from the hospital when the ventilator has stoppedall the miles of polyethylenepulling and pushing fluids before,now hang limp, to no avail?The kitchen, the mirrors, the bedwhere you both rested headsG-d, not his pillowNo, not his closet and the clotheshe'll never wear.Only a shroud covering his face hovering over the rest of lifemay as well drape over the house,house that was once collectively yours that now seems so much hisHow do you cook and contend answer the phone look at the mail pray for an endNeed you bother?What do you do when you come from the ... Author, Article, and Disclosure InformationAffiliations: From Atlanta, Georgia.Current Author Address: Stanley Cohen, MD, Children's Center for Digestive Health Care, 993D Johnson Ferry Road, #440, Atlanta, GA 30342; e-mail, [email protected]com. PreviousarticleNextarticle Advertisement Audio Reading - “Deescalation” Audio. Michael A. LaCombe, MD, Annals Associate Editor, reads "Deescalation," by S. Cohen. Your browser does not support the audio element. Audio player progress bar Step backward in current audio track Play current audio trackPause current audio track Step forward in current audio track Mute current audio trackUnmute current audio track 00:00/ FiguresReferencesRelatedDetails Metrics 5 January 2016Volume 164, Issue 1Page: 61KeywordsChild healthChildrenCombined antiretroviral therapyHealth careOintmentsStainingVentilators ePublished: 5 January 2016 Issue Published: 5 January 2016 Copyright & PermissionsCopyright © 2016 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
THE GALASSI-GIFFORD PUPILARY REACTION.
Journal: JAMA (1900)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Tubal ligation, hysterectomy, and risk of ovarian cancer. A prospective study
Authors: S. E. Hankinson
Journal: JAMA (1993)

<h3>Objective.</h3> —To assess whether tubal ligation and hysterectomy affect subsequent risk of ovarian cancer. <h3>Design.</h3> —Prospective cohort study with 12 years of follow-up. <h3>Setting.</h3> —United States, multistate. <h3>Participants.</h3> —A total of 121 700 female registered nurses who were 30 to 55 years of age in 1976; the follow-up rate was 90% as of 1988. <h3>Main Outcome Measure.</h3> —Ovarian cancer of epithelial origin confirmed by medical record review. <h3>Results.</h3> —We observed a strong inverse association between tubal ligation and ovarian cancer, which persisted after adjustment for age, oral contraceptive use, parity, and other ovarian cancer risk factors (multivariate relative risk [RR] 0.33; 95% confidence interval [CI], 0.16 to 0.64). The association was similar when we assessed tubal ligation status at the baseline questionnaire and excluded cases in the first 4 years to eliminate any possible short-term decrease in risk due to screening of the ovaries during ligation surgery. We noted a weaker inverse association between simple hysterectomy and ovarian cancer (RR, 0.67; 95% CI, 0.45 to 1.00). Neither vasectomy nor condom use by a partner was associated with risk of ovarian cancer. <h3>Conclusions.</h3> —These data indicate that tubal ligation, and perhaps hysterectomy, may substantially reduce risk of epithelial ovarian cancer. (<i>JAMA</i>. 1993;270:2813-2818)
Book Review Clinical Endocrinology of the Female . By Charles Mazer, M.D., F.A.C.S., Assistant Professor of Gynecology and Obstetrics, Graduate School of Medicine, University of Pennsylvania; Gynecologist to Mt. Sinai and Northern Liberties Hospitals, Philadelphia; and Leopold Goldstein, M.D., Demonstrator of Obstetrics, Jefferson Medical College; Assistant Gynecologist to Mt. Sinai Hospital; Formerly Fellow in Gynecologic Research, University of Pennsylvania. 518 pages with 117 illustrations. …
Journal: New England Journal of Medicine (1933)
Two for the price of one. New hospitals at Bury St. Edmunds and at Frimley.
Journal: BMJ (1968)

Two for the Price of One At a press conference on 1 April the Minister of Health introduced the plans for new district general hospitals at Bury St. Edmunds, Suffolk, and at Frimley, Surrey, the latest product of the Ministry's own design and planning team.The striking innovation in the designs is that the two hospitals are virtually identical, though the areas differ -one is largely agricultural and the other mixed agricultural and industrial.The new design incorporates features intended to encourage the development of community medical services based on the hospital, and facilities for day- surgery and better outpatient services have been included.
Radiation Incidents
Journal: JAMA (2001)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Doctors and Overpopulation
Authors: J. A. D. Anderson, J. C. Briggs, W. J. H. Butterfield, C. O. Carter, N. Dodd, G. A. W. Dove, D. Dunlop, P. N. Edmunds, D. V. I. Fairweather, C. M. Fletcher, R. F. Fletcher, A. Gillie, J. Guillebaud, J. M. Holmes, J. P. Horder, P. J. Horsey, S. Jain, J. S. Johnstone, C. R. Kay, D. M. Kerslake, J. P. Lester, J. A. Loraine, J. Luder, T. D. Lusty, N. MacDonald, J. McEwan, D. M. MacLaren, M. C. MacNaughton, S. Maneksha, E. Mears, D. A. Morgan, G. M. Morris, J. G. Neill, L. T. Newman, D. A. Ll. Owen, J. Pemberton, G. Pickering, M. D. Rawson, S. G. Rubin, A. S. Rudd, K. E. Schopflin, E. T. O. Slater, M. V. Smith, E. M. Steiner, I. T. Stuttaford, G. I. M. Swyer, V. Tonge, J. A. P. Trafford, M. E. Tuck, S. C. Tuck, G. R. Venning, M. P. Winstanley
Journal: BMJ (1972)
From the Assistant Secretary for Health, US Public Health Service
Authors: James O. Mason
Journal: JAMA (1991)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Serum angiotensin converting enzyme activity in patients with histoplasmosis
Authors: K. W. Ryder
Journal: JAMA (1983)

The association between increased serum angiotensin converting enzyme (ACE) activity and active sarcoidosis is well documented. During a recent outbreak of acute histoplasmosis, a disease that shares many of the clinical and roentgenographic features of sarcoidosis, we examined serum ACE activity. Twenty-one (25%) of 86 patients with histoplasmosis had increased serum ACE activity. There were neither roentgenographic nor other substantive clinical differences between the groups of patients with increased and normal ACE values. Therefore, an increase in serum ACE activity must not be assumed to be caused by sarcoidosis unless histoplasmosis had been excluded. (<i>JAMA</i>1983;249:1888-1889)
Nontraumatic Rhabdomyolysis
Authors: MARTIN R. LIEBOWITZ
Journal: Annals of Internal Medicine (1977)

Comments and Correction1 April 1977Nontraumatic RhabdomyolysisMARTIN R. LIEBOWITZ, M.D.MARTIN R. LIEBOWITZ, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-86-4-510_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: The recent paper by Koffler and associates (1) is an admirably documented addition to the literature on muscle injury and renal failure after narcotic and sedative overdose. I do have a concern, however, about the use of the designation "nontraumatic rhabdomyolysis". The literature on this subject, some of which is cited by the authors, points to the traumatic origin (compression during unconsciousness) of this syndrome in most instances. Indeed, the authors indicate that 17 of their 18 patients were either lethargic or in coma and that muscle swelling was present in 11. Two patients required fasciotomy and...References1. KOFFLERFRIEDLERMASSRY ARS: Acute renal failure due to nontraumatic rhabdomyolysis. Ann Intern Med 85:23-28, 1976 LinkGoogle Scholar2. SCHREIBERLIEBOWITZBERNSTEIN SML: Limb compression and renal impairment (crush syndrome) following narcotic and sedative overdose. J Bone Joint Surg [Am] 54:1683-1692, 1972 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Department of Medicine South Nassau Communities Hospital 2445 Oceanside Road Oceanside, NY 11572 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 April 1977Volume 86, Issue 4Page: 510-510KeywordsComaInflammationMusclesRenal failureRhabdomyolysisSedatives Issue Published: 1 April 1977 PDF DownloadLoading ...
BASEM Congress 2001
Authors: C Martin, A Clark
Journal: British Journal of Sports Medicine (2002)

The 12 greenstick # and one displaced distal radius # occurred in children.The remaining fractures were in adults.Three further patients were initially diagnosed as having a "clinical scaphoid #" who were later found to have no radiological evidence of scaphoid injury on further examinations.There were also seven soft tissue injuries to the wrist. Abstract 1 Percentage of women exceeding recommended exercise guidelines in pregnancyTrimester of pregnancy Athletic group Practice group 1-3 51 24 2-6 25 14 6-9 9 5 150 100 0 50 3rd trimester Running Very hard Av.time (mins) 2nd trimester Pre-pregnancy 1st trimester Hard Somewhat hard Fairly light www.bjsportmed.com
Conditions de réalisation de l'endoscopie digestive en France en 2005: résultat d'une enquête prospective nationale de la Société Française d'Endoscopie Digestive (SFED)
Authors: JM Canard, JP Arpurt, C Boustière, J Boyer, J Cassigneul, PA Dalbies, J Escourrou, G Gay, R Laugier, JC Letard, B Napoléon, L Palazzo, T Ponchon, B Richard-Molard, D Sautereau, G Tucat, B Vedrenne
Journal: Endoscopy (2007)

Le but de ce travail a été de décrire et de quantifier les conditions de réalisation de l'endoscopie digestive en France et son évolution depuis 1998.
Editorial Responsibilities— Editorial Procedures
Journal: JAMA (1969)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Protection From Reperfusion Injury After Cardiac Transplantation by Inhibition of Adenosine Metabolism and Nucleotide Precursor Supply
Authors: Ryszard T. Smolenski, Olivier Raisky, Ewa M. Slominska, Haitham Abunasra, Kameljit K. Kalsi, Jay Jayakumar, Ken Suzuki, Magdi H. Yacoub
Journal: Circulation (2001)

Background Adenosine (Ado) triggers numerous protective mechanisms in the heart that may attenuate ischemia-reperfusion injury in cardiac grafts. We aimed to establish whether sustained increase in endogenous Ado production by the combined application of Ado metabolism inhibitors and nucleotide precursors attenuates reperfusion injury in transplanted hearts. Methods and Results Rat hearts were collected after the infusion of St Thomas’ Hospital cardioplegic solution, stored at 4°C for 4 hours, and heterotopically transplanted into the abdomen of recipient rats. A solution containing Ado deaminase inhibitor erythro-9(2-hydroxy-3-nonyl)adenine, Ado kinase inhibitor 5′-aminoadenosine, and nucleotide precursors adenine and ribose was administered at the time of reperfusion in the treated group, whereas saline was administered to control animals. After 1 or 24 hours, mechanical function of the transplanted hearts was evaluated in an ex vivo perfusion system followed by the determination of myocardial ATP with related metabolites and measurement of the activity of neutrophil-specific enzyme myeloperoxidase in cardiac homogenates. After 24 hours of reperfusion, maximum left ventricular developed pressure increased from 87.0±6.8 mm Hg (mean±SEM) in controls to 118.1±8.2 mm Hg in the treated group ( P &lt;0.05), ATP increased from 11.0±0.8 μmol/g dry wt in controls to 15.1±1.2 μmol/g dry wt in the treated group ( P &lt;0.01), and myeloperoxidase activity decreased from 2.23±0.60 U/g wet wt in controls to 0.58±0.12 U/g wet wt in the treated group ( P &lt;0.001). No differences in cardiac function, ATP, or myeloperoxidase activity were observed between the treated group and controls after 1 hour of reperfusion. Conclusions The administration of Ado metabolism inhibitors with nucleotide precursors causes a sustained increase in endogenous Ado production and exerts a potent protective effect against reperfusion injury in transplanted hearts. Improved cardiac function and elevated ATP concentration were accompanied by complete amelioration of neutrophil infiltration in treated hearts, suggesting that reduction in postischemic inflammation could be an important mechanism of this protective effect.
Annual Dinner of the Members of the Medical Benevolent Fund
Journal: BMJ (1842)

AT APOTHECARIES' HALL.197 within a quarter of an inch.On the bottom of the wound lay the thyroid axis exposed to view, and from it given off the iniferior thyroid, runniing upwards and forwards, and destroyed by ulceration in one half of its circumference for the space of ani inch.The ulcerative process involved, to a slight extentt, the tlhyroid axis itself.The thyroid artery, beyond the ulcerated opening, was completely obliterated, show- ing previous inlflammation of the artery.Indeed, it would appear probable that the whole of the thyroid artery had been obliterated by coagula before the ulceration commenced, acd it is probable that the whole of the artery would soon have beeni destroyed without danger, had not the ulcerationi reached the thyroid axis.This, of course, was not protected by coagula, and as soon as its coats were penetrated,
A Novel Pathway to the Ultimate Mutagens of Aromatic Amino and Nitro Compounds
Authors: Dieter Wild
Journal: Environmental Health Perspectives (1990)

Photolysis of arylazides in aqueous media was recently found to generate presumed nitrenium ions, species which are generally considered as the ultimate mutagens/carcinogens derived from arylamines and nitroarenes. The primary photolysis products of arylazides, the arylnitrenes, can possibly react as electrophiles themselves, or they can be protonated and thus form the electrophilic nitrenium ions. Numerous arylazides and aryldiazides can be photoactivated to short-lived mutagens detectable in Salmonella typhimurium TA98. Structure-activity comparisons between arylazides and the matching arylamines and nitroarenes show correlations; e.g., phenyl azide and methyl-substituted phenyl azides are not mutagenic or only weakly mutagenic like aniline, nitrobenzene, and their methyl homologues, whereas 4-azidodiphenyl, 2-azidofluorene, 1-azidopyrene, azido-IQ, and azido-isoIQ are increasingly mutagenic in that order, like the matching amino and nitro compounds. It is hypothesized on the basis of these data that the nitrene/nitrenium ion is the reactive intermediate common to the three mutagenic pathways and that the reaction of the nitrene/nitrenium ion with DNA is rate limiting for the overall mutagenic process in Salmonella. The photochemical generation from arylazides of the reactive species, the nitrene/nitrenium ions, opens new perspectives for the understanding of the genotoxic activity of arylamines and nitroarenes in general and, specifically, of the food mutagens/carcinogens of the IQ type.
Recommendations from the International Workshop on the Epidemiology of Insulin-dependent Diabetes Mellitus Philadelphia, Pennsylvania October 1983
Journal: Diabetes Care (1985)

The workshop resulted in 23 recommendations that represent major areas of needed epidemiologic research focused on IDDM. They are subdivided here according to the four conference sessions. Each recommendation is followed by a brief rationale. All recommendations are considered to be high priority, and are not ranked relative to one another.
Pulse Oximetry During Conscious Sedation
Authors: Mark A. Chaney
Journal: JAMA (1994)

<h3>To the Editor.</h3> —As an anesthesiologist who uses pulse oximeter technology daily, I read with great interest the American Medical Association Council on Scientific Affairs report.<sup>1</sup>It is vital to realize that pulse oximetry reveals nothing regarding adequacy of ventilation. Although this important point was addressed briefly in the Council's report, I feel it deserves greater emphasis. Too often, physicians become complacent when arterial oxygen saturation is normal. In pioneering work detailing physiology of apneic oxygenation, Frumin and colleagues<sup>2</sup>induced periods of apnea in eight subjects lasting 18 to 55 minutes while simultaneously insufflating oxygen endotracheally at rates of 200 mL/min. The lowest arterial oxygen saturation recorded was 98%, yet profound hypercarbia was documented. In one individual, apnea lasted 53 minutes and the lowest arterial oxygen saturation recorded was 98%, yet at the same time the arterial carbon dioxide tension has increased to 250 mm Hg and the