tbuckley/cabot-search huggingface dataset:
Incorrect Data.
Journal: JAMA (1997)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Error in Byline Order
Journal: JAMA Network Open (2018)

John Barton Jemmott III, PhD; Ann O’Leary, PhD; Loretta Sweet Jemmott, PhD, RN; Zolani Philemon Ngwane, PhD; Anne Marie Teitelman, PhD, FNP-BC; Monde Blessing Makiwane, PhD; Scarlett L. Bellamy, ScD
Antibiotic resistance and topical treatment.
Journal: BMJ (1978)

which at times resemble frank convulsions and may persist into the recovery period.16Propanidid causes more cardio- vascular depression than thiopentone, methohexitone, and Althesin, which are similar in their effects on blood pressure.8Etomidate causes minimal cardiorespiratory depression.'4Propanidid, which is rapidly metabolised,8 is the shortest acting of these drugs.Recovery after methohexitone is more rapid than with thiopentone, Althesin,8 and etomidate.'6Propanidid is associated with a high incidence of post- anaesthetic nausea and vomiting (up to 400), while Althesin causes the lowest incidence of sickness.8The balance of advantage would be tipped towards Althesin were it not for the relatively high incidence of anaphylactic or anaphylactoid reactions.Most of these are minor or transient skin reactions, but some are more serious and require active treatment.Many anaesthetists believe that the desirable properties of Althesin outweigh its disadvantages, and they avoid using it only in patients known to be predisposed to allergic reactions'7 and those with asthma, hay fever, eczema, or a known sensitivity to drugs.For the time being thiopentone will remain the drug of first choice for most anaesthetists.
TREATMENT OF LEPROSY WITH THE DEAN DERIVATIVES OF CHAULMOOGRA OIL
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
慢性荨麻疹和骨质疏松
Authors: G. Shalom, K. Kridin, M. Babaev, E. Magen, S. Tiosano, J. Dreiher, A. Horev, R. Khury, D. Comaneshter, N. Agmon‐Levin, A.D. Cohen
Journal: British Journal of Dermatology (2019)

骨质疏松是一种骨骼变薄和更易于骨折的疾病。它在女性和年龄大于 50 岁人中更常见。它不能被治愈,因此重点在于预防,即意味着发现和处理风险因素,如肥胖、维生素 D 摄入少、慢性炎症和长期使用类固醇药物。慢性荨麻疹(风团,CU)是一种炎症性疾病,因此有人预计它可能与骨质疏松有关,但从未有人调查。如果 CU 患者真的更可能发生骨质疏松,可以就预防措施为其提供建议。为此,来自以色列的医生们调查了来自一个涵盖 450 万人的大型医学数据库中的 11,944 名诊断为 CU 的患者。一个潜在困难是 CU 患者更多为女性、肥胖且曾接受过系统类固醇治疗,这些都会增加骨质疏松的风险。因此,对于每名 CU 患者,他们研究了 5 名年龄和性别匹配的对照患者(年龄和性别相同,但无 CU),且他们的分析考虑了骨质疏松的其他已知风险因素。在 16 年中,8.7% 的 CU 患者被诊断为骨质疏松,而对照组只有 6.8%。他们得出结论,CU 是骨质疏松虽小但重要的额外风险因素。一篇随附的社论警告说,不能基于可能并未包含所有需要信息的常规健康记录来得出结论。尽管如此,治疗慢性荨麻疹的医生可能需要认识到他们患者有发生骨质疏松的风险,并给予相应咨询。
Artificial Insemination
Authors: W. Gilliatt
Journal: BMJ (1945)

<h3>Abstract</h3> The neurotransmitter serotonin (5-HT) is considered a powerful modulator of sensory system organization and function in a wide range of animals. The olfactory system is innervated by midbrain 5-HT neurons into both its primary and secondary odor-processing stages. Facilitated by this circuitry, 5-HT and its receptors modulate olfactory system function, including odor information input to the olfactory bulb. It is unknown, however, whether the olfactory system requires 5-HT for even its most basic behavioral functions. To address this question, we established a conditional genetic approach to specifically target adult brain <i>tryptophan hydroxylase 2</i> (<i>Tph2</i>), encoding the rate-limiting enzyme in brain 5-HT synthesis, and nearly eliminate 5-HT from the mouse forebrain. Using this novel model, we investigated the behavior of 5-HT–depleted mice during performance in an olfactory go/no-go task. Surprisingly, the near elimination of 5-HT from the forebrain, including the olfactory bulbs, had no detectable effect on the ability of mice to perform the odor-based task. <i>Tph2</i>-targeted mice not only were able to learn the task, but also had levels of odor acuity similar to those of control mice when performing coarse odor discrimination. Both groups of mice spent similar amounts of time sampling odors during decision-making. Furthermore, odor reversal learning was identical between 5-HT–depleted and control mice. These results suggest that 5-HT neurotransmission is not necessary for the most essential aspects of olfaction, including odor learning, discrimination, and certain forms of cognitive flexibility.
<i>Annual of the Universal Medical Sciences. A yearly report of the progress of the general sanitary sciences throughout the world.</i>Edited by Charles E. Sajous, M. D., and seventy associate editors. The F. A. Davis Company, Publishers, 1892
Authors: A. M.
Journal: American Journal of Psychiatry (1892)

In acute delirium, the author says, under the head of treatment:"Even though bodily prostration is apt to come on early and be profound, 1 would not hesitate to advise, in the case of a robust man, free venesection.it is not at all improbable that some of the many cases of mania in which Benjamin Rm h let blood with such benefit belonged to this class of affections.Considering its remarkable calming influence in febrile delirium, the cold bath or the cold pack should be employed.Morphia and chloroform may be administered, and hyoscine and the bromides may be tried.Krafft.Ebing states that Solivetti has obtained good results by the use of ergotin.TJnfor-
Pulse
Journal: JAMA (1994)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Effect of surgeon specialty on outcomes for ovarian cancer
Authors: C. C. Earle, D. Schrag, B. A. Neville, R. Yabroff, M. Topor, A. Fahey, J. Warren
Journal: Journal of Clinical Oncology (2004)

6027 Background: Specialized care has been associated with superior quality care for many diseases, but has not been previously examined for ovarian cancer surgery. Methods: We analyzed the Medicare claims of all patients undergoing surgery for ovarian cancer diagnosed while living in areas monitored by the Surveillance, Epidemiology, and End Results (SEER) program between 1992–1999. Claims were linked to American Medical Association files to determine provider type. Results: Among 3,067 patients who underwent surgery, gynecologic oncologists (GO) operated on 31% of patients, gynecologists (G) 41%, and non-specialist surgeons (S) the remaining 28%. Rates of specialized care increased over the study period from 25% to 37% (P<.0001), and varied geographically with more patients in the Northeast and South having GO than those in the Midwest and West (P<.0001). Other factors associated with being operated on by a gynecologic specialist on both univariate and multivariate analyses were: younger age (Odds Ratio (OR) .97, 95% Confidence Interval (CI) .96-.99) for each increasing year, black race (OR 1.73, 1.2–2.5), and more advanced (stage III/IV) disease (OR 1.48, 1.2–1.81). Compared to S, patients of GO were less likely to require multiple surgeries in the peri-diagnostic period (3% vs 5%, P=.05). Patients with stage III or IV disease managed by GO were more likely to undergo a debulking procedure or have a lymph node dissection (64% vs. 27%, P<.0001) at the time of their first surgery, less likely to require an ostomy (18% vs. 25%, P<.0001), and less likely to undergo second-look laparotomies (14% vs. 18%, P<.0001). They were also more likely to receive chemotherapy in the subsequent 12 months (79% vs 68%, P<.0001). There were no clear differences in rehospitalization or complication rates. Cox modeling suggested an adjusted hazard ratio of 0.89 (CI .80-.98) for patients receiving specialized care. Conclusions: Initial management of advanced ovarian cancer by specialist surgeons may be associated with better quality of care and outcomes. No significant financial relationships to disclose.
Correction: Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies
Authors: Iris Broce, Celeste M. Karch, Natalie Wen, Chun C. Fan, Yunpeng Wang, Chin Hong Tan, Naomi Kouri, Owen A. Ross, Günter U. Höglinger, Ulrich Muller, John Hardy, Parastoo Momeni, Christopher P. Hess, William P. Dillon, Zachary A. Miller, Luke W. Bonham, Gil D. Rabinovici, Howard J. Rosen, Gerard D. Schellenberg, Andre Franke, Tom H. Karlsen, Jan H. Veldink, Raffaele Ferrari, Jennifer S. Yokoyama, Bruce L. Miller, Ole A. Andreassen, Anders M. Dale, Rahul S. Desikan, Leo P. Sugrue
Journal: PLoS Medicine (2018)

[This corrects the article DOI: 10.1371/journal.pmed.1002487.].
LETTER FROM NEW YORK.
Authors: None P. B. P.
Journal: JAMA (1889)

(FROM OUR OWN CORRESPONDENT.) New York Academy of Medicine—Section on Practice—Simulo in the Treatment of Epilepsy--The Significance of the Crepitant Râle, etc. At the last meeting of the Section on Practice of the Academy of Medicine, Dr. M. Allen Starr read a report of the new drug simulo in the treatment of epilepsy. Like others, his attention was first directed to the subject by the article of Dr. W. H. White, which appeared in<i>The Lancet</i>in March, 1888, and he gave a<i>résumé</i>of the observations of White and also those of Eulenberg, of Berlin, published in August, 1888. White reported seven cases treated by this agent, all of them being cases in which renal fits occurred every week. In the first case neither simulo or bromide was of any particular benefit. In the other cases there was considerable improvement under the use of simulo, and in case number
QL-22 * QUICK, NON INVASIVE AND QUANTITATIVE EVALUATION OF SMALL FIBER NEUROPATHY IN PATIENTS RECEIVING CHEMOTHERAPY
Authors: M. Saad, C. Tafany, M.-L. Nevoret, D. Ricard
Journal: Neuro-Oncology (2014)

Early stages of chemotherapy-induced peripheral neurotoxicity (CIPN) are poorly investigated due to the lack of simple tool. SUDOSCAN is a simple, quick (<3 minutes), non-invasive and quantitative method to assess small fiber neuropathy, based on an electrochemical reaction between sweat chlorides and stainless-steel electrodes. This study aimed to evaluate SUDOSCAN in the detection and follow-up of early CIPN. 15 patients receiving Oxaliplatin (12 males, mean age: 60 ± 10years) and 16 Paclitaxel (6 males, mean age: 64 ± 15 years) were involved in the study. At each chemotherapy infusion cumulative dose of chemotherapy was calculated, Total Neuropathy Score (TNSc) was performed and Electrochemical Skin Conductances (ESC) of hands and feet expressed in microSiemens (µS) were assessed by SUDOSCAN. For patients receiving Oxaliplatin hands ESC changed from 78 ± 9 to 68 ± 14 µS (p < 0.0001) and feet ESC from 82 ± 10 to 75 ± 14 µS (p = 0.0005) while TNSc changed from 3.3 ± 4.3 to 3.6 ± 2.6 (p = 0.001) for mean cumulative dose changing from 250 ± 264 to 429 ± 248 (mg/m2). In patients receiving Paclitaxel hands ESC changed from 62 ± 20 to 44 ± 18 µS (p < 0.0001) and feet ESC from 72 ± 18 to 60 ± 20 µS (p = 0.0005) while TNSc changed from 5.8 ± 2.2 to 6.3 ± 2.4 (p = 0.001) for mean cumulative dose changing from 1180 ± 1255 to 1507 ± 1380 (mg/m2). When looking at asymptomatic patients mean TNSc changed from 3 ± 3 to 4 ± 3 (p = 0.0002). Mean hands ESC changed from 66 ± 20 µS to 55 ± 21 µS (p < 0.0001), while mean feet ESC changed from 71 ± 21 µS to 64 ± 23 µS (p < 0.0001), suggesting that SUDOSCAN could help detect and quantify CIPN even in asymptomatic patients. This preliminary study demonstrated that small fiber neuropathy can be followed using SUDOSCAN in patients receiving chemotherapy. These preliminary results observed during on-going chemotherapy must be confirmed in a larger population with measurements performed before the initiation of chemotherapy and during its follow-up.
Schweizerische Medizinische Wochenschrift, Basel
Journal: JAMA (1969)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Cholangiography
Authors: John F. Morrissey
Journal: New England Journal of Medicine (1973)

Rösch et al., in this issue of the Journal, describe the largest series as yet reported of transjugular cholangiography, and introduce an improved technic for the performance of transjugular needle liver biopsy. They obtained useful diagnostic information from the new technics with roughly the same frequency that would be expected from the simpler procedures of percutaneous transhepatic cholangiography and percutaneous needle liver biopsy. Increased safety is the major advantage claimed for the new methods because it is nearly always possible to avoid puncturing the liver capsule when the transjugular approach is used, particularly if the vascular anatomy of the . . .
Balanced salt solution in the treatment of hemorrhagic shock. Studies in dogs
Authors: R. N. McClelland
Journal: JAMA (1967)

Previous studies show a decreased mortality from hemorrhagic shock when Ringer's lactate solution is given intravenously in addition to replacement of shed blood. The improved survival rate seems related to restoration of a disproportionate extracellular fluid reduction occurring with hemorrhagic shock.<sup>1</sup> The objectives of this study were (1) to define some of the physiological effects of the treatment of hemorrhagic shock with blood replacement and Ringer's lactate solution, and (2) to investigate the theoretical objection that Ringer's lactate solution may aggravate lactic acidosis when used to treat shock. <h3>Materials and Methods</h3> Twenty-four previously splenectomized mongrel dogs ranging in weight from 17 to 26 kg (38 to 58 lb) were anesthetized with pentobarbital given intravenously and breathing was controlled by a respirator using room air. Bilateral femoral artery and vein and external jugular vein cannulizations were done. Mean femoral arterial blood pressure and pulse rate were monitored continuously with a
Questionable cancer practices in Tijuana and other Mexican border clinics
Journal: CA A Cancer Journal for Clinicians (1991)

Tijuana, Mexico, has become a refuge for cancer patients who have been convinced that they may be cured of their terminal illness by unconventional, unproved, and disproved methods offered in the border clinics. About a dozen United States promoters have joined with Mexican colleagues to offer a variety of treatments. Some patients are diagnosed using standard methods prior to arrival at the clinics, but many healthy individuals are misdiagnosed as having cancer or "precancer" and are then treated there. Others are told they have been cured or are improving even though they still have active disease. The modalities and regimens used are often referred to as "metabolic therapy" and, for the most part, are either not based on sound scientific principles or have been shown in controlled clinical trials to be useless or even dangerous. A basic metabolic regimen consists of three phases: detoxification with fasting and bowel cleansing, strengthening the immune system with numerous "supplements," and attacking cancer with "natural and non-toxic" chemicals. Popular treatments include injections of hydrogen peroxide, large quantities of pressed liver and carrot juice, coffee enemas, infusions of Laetrile mixed with massive doses of vitamins and dimethylsulfoxide (DMSO), special diets, and a host of other pseudoscientific regimens. Unfortunately, no evidence exists that any of these modalities is more effective than no treatment at all. Patients traveling to the Mexican border clinics for metabolic therapy are subjecting themselves to costly and hazardous regimens, especially if they forgo responsible medical care in the process. The American Cancer Society, therefore, strongly urges individuals with cancer not to seek treatment with metabolic therapies in the Mexican border clinics.
COUNCIL ON PHARMACY AND CHEMISTRY
Journal: JAMA (1953)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Results of the Pegasus Phase 3 Randomized Trial Demonstrating Superiority of the C3 Inhibitor, Pegcetacoplan, Compared to Eculizumab in Patients with Paroxysmal Nocturnal Hemoglobinuria
Authors: Peter Hillmen, Jeffrey Szer, Ilene C. Weitz, Alexander Röth, Britta Hoechsmann, Jens Panse, Kensuke Usuki, Morag Griffin, Jean-Jacques Kiladjian, Carlos M. de Castro, Hisakazu Nishimori, Lisa Tan, Mohamed Hamdani, Pascal Deschatelets, Cedric Francois, Federico Grossi, Antonio Risitano, Regis Peffault De Latour
Journal: Blood (2020)
Applications of a Versatile Technique for Trace Analysis: Atmospheric Pressure Negative Chemical Ionization
Authors: B. A. Thomson, W. R. Davidson, A. M. Lovett
Journal: Environmental Health Perspectives (1980)

The ability to use ambient air as a carrier and reagent gas in an atmospheric pressure chemical ionization source allows instantaneous air analysis to be combined with hypersensitivity toward a wide variety of compounds. The TAGA (Trace Atmospheric Gas Analyser) is an instrument which is designed to use both positive and negative atmospheric pressure chemical ionization (APCI) for trace gas analysis; this paper describes several applications of negative APCI which demonstrates that the technique is not limited to environmental monitoring. Examples are described which suggest that the TAGA can be used for the detection of illicit drugs and explosives, and for the analysis of breath or skin emissions, as well as for air pollution measurements. The applications are not restricted by the use of ambient air as a reagent gas; addition to the air carrier of various gases allows specific reagent ions such as Cl- or Br- to be generated. Furthermore, in certain situations pure gas carriers can be used to provide even more flexibility in the ion chemistry, with a short term absorber-desorber system used to transfer the sample from the ambient air into the ion source region. The potential uses for APCI are expanding continuously as the understanding of the complex ion-molecule chemistry grows. This paper underlines the complementary relation between the development of new negative chemical ionization (NCI) techniques and practical applications using the TAGA system.
Minimising the risk of salmonellosis from eggs
Authors: Collective Editorial Committee
Journal: Eurosurveillance (1997)

Outbreaks of Salmonella enteritidis associated with raw eggs continue to be common, despite the risk of using raw eggs being well known. In many cases S. enteritidis isaself-limitingillnessbut- particularlyinvery young and very old people - it can be seve