tbuckley/cabot-search huggingface dataset:
Congestive Heart Failure
Authors: CLEMENT J. MCDONALD
Journal: Annals of Internal Medicine (1977)

Letters and Corrections1 July 1977Congestive Heart FailureCLEMENT J. MCDONALD, M.D.CLEMENT J. MCDONALD, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-87-1-119 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: I appreciate the enlightenment that Harlan and associates (1) have provided with their article on congestive failure. Their data provide the beginnings of a rational, quantified framework for making clinical decisions about congestive failure.If one accepts the authors' criterion for congestive failure (left end diastolic pressure greater than 15 mm Hg), one must conclude that the medical community habitually underdiagnoses congestive failure, since the most sensitive objective indicator (cardiomegaly) is false-negative 38% of the time. However, this conclusion depends on the validity of the authors' criterion for congestive failure. The fact that only 66% of these...References1. HARLAN W, OBERMAN A, and GRIMM R: Chronic congestive heart failure in coronary artery disease: clinical criteria. Ann Intern Med 86:133-138, 1977 LinkGoogle Scholar2. GLOVER L, BAXLEY W, and DODGE H: A quantitative evaluation of heart size measurements from chest roentgenograms. Circulation 47:1289-1296, 1973 CrossrefMedlineGoogle Scholar1. GALEN R and GAMBINO S: Beyond Normality. New York, John Wiley and Sons, 1975, pp. 50-113 Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: CLEMENT J. MCDONALD, M.D.Affiliations: Department of Medicine Indiana University School of Medicine Indianapolis, IN 46202 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 July 1977Volume 87, Issue 1Page: 119-120KeywordsBlood pressureDecision makingHeart failure ePublished: 1 December 2008 Issue Published: 1 July 1977 PDF downloadLoading ...
Exsanguination Transfusion in Hemolytic Disease of the Newborn
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Lullaby
Authors: Dzvinia Orlowsky
Journal: JAMA (2020)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
RESPONSE: Re: Breast-Conserving Surgery With or Without Radiotherapy: Pooled-Analysis for Risks of Ipsilateral Breast Tumor Recurrence and Mortality
Authors: V. Vinh-Hung, C. Verschraegen, M. Royce, J. Van de Steene, P. Tai, G. Cserni, G. Storme, G. Vlastos
Journal: JNCI Journal of the National Cancer Institute (2004)
Strategies for screening blood for human immunodeficiency virus antibody. Use of a decision support system
Authors: J. S. Schwartz
Journal: JAMA (1990)

A decision analytic model was used to examine alternative strategies to screen donated blood for human immunodeficiency virus (HIV) using data from the literature and from 1987 blood-screening programs in areas with high and low prevalence of HIV. Sensitivity analyses incorporated uncertainties about HIV infection and test performance. Current screening strategies are estimated to allow 20.5 infected units per million donated units to be transfused at a cost of $16 850 per HIV-positive unit detected in high-prevalence areas and 4.7 infected units per million donated units to be transfused at a cost of $32 275 per HIV-positive unit detected in low prevalence areas, with nine false-positive notifications of uninfected patients per million units screened and 14.9 discarded, noninfected units per HIV-positive unit in low-prevalence areas. Testing donated blood for HIV can be improved by individualizing screening strategies for areas with different prevalences of HIV. Efforts to further reduce transfusion-associated HIV should focus on improved test performance in early stages of infection, reduction of unnecessary transfusions, donor recruitment in lower-risk groups, and public health measures to reduce HIV infection among the general population. (<i>JAMA</i>. 1990;264:1704-1710)
Medical schools receive a message: reform yourselves, then take on health care system
Authors: P. Cotton
Journal: JAMA (1991)

MEDICAL SCHOOLS may need to become more active in health care reform, first by reforming themselves. Outmoded department structures and relationships, didactic lectures, hospital-based teaching, and patient care financing all may be contributing to the health care crisis by promoting expensive, sub-specialist, high-technology interventions late in disease at the expense of primary care and prevention. These are among points made by speakers at a conference on the future of medical education, held at the University of Chicago (Ill). <h3>AMA Looks to 21st Century</h3> (While medical educators are pondering these points, the American Medical Association's Section on Medical Schools will be meeting the first weekend in December at the Las Vegas [Nev] Hilton Hotel. Among other things, attendees will hear a keynote address on "Medicine in the 21st Century.") At the future of medical education conference, one of the speakers—Alvin R. Tarlov, MD—said that the 20th century shift from acute infectious
Glucose insulin potassium infusion improves systolic function in patients with chronic ischemic cardiomyopathy Yves Cottin, Laurent Gilson, Isabelle L'Huillier, Marianne Zeller, Christine Toulouse, Luc Rochette, Claude Girard, Jean-Eric Wolf. Cardiology Department, Dijon, France, Anaesthesiology Department, Dijon, France
Journal: Journal of the American College of Cardiology (2001)
The Pathogenesis of Renal Insufficiency
Authors: Stanley E. Bradley
Journal: New England Journal of Medicine (1945)

IN POPULAR usage, the expression "renal insufficiency" has come simply to mean renal failure to maintain chemical homeostasis. In a restricted sense, however, there may be many renal insufficiencies. The acid–base balance may be maintained, while nitrogen accumulates in the blood, and conversely, nitrogen excretion may be unaltered when acidosis and dehydration result from urinary loss of water and electrolytes. Water reabsorption, nitrogen excretion or sodium conservation may each be affected individually, but in most disorders of renal function and structure, renal dysfunctions and their sequelae are multiple. The discussion that follows is devoted to a consideration of the pathologic . . .
THE DANGER OF DOGMATISM IN SCIENTIFIC FIELDS
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract P263: Racial Differences in the Association Between Physical Activity Levels During Early Adulthood and Visceral Adiposity at Middle Age: The CARDIA Study
Authors: Christina M Shay, Laura A Colangelo, Mercedes R Carnethon, Kiarri N Kershaw, Cora E Lewis, Jared P Reis, Megan R Sands, James M Shikany, David S Siscovick, J Greg Terry, J Jeffrey Carr, David R Jacobs
Journal: Circulation (2012)

Background: Excess visceral adiposity tissue (VAT) is associated with elevated free fatty acids that contribute to dyslipidemia, beta cell dysfunction, and insulin resistance. Greater physical activity (PA) is associated with lower VAT cross-sectionally, but whether PA during young adulthood is associated with VAT at middle age independent of general obesity is unclear. Objective: To quantify by sex and race the associations between PA levels in young adulthood with visceral adiposity measured 25 years later. Methods: The Coronary Artery Risk Development in Young Adults (CARDIA) study is a population-based, prospective, observational study of black and white men and women. Habitual PA was determined as the average of baseline and year 7 levels (18–37 yrs) of the CARDIA Physical Activity Score. VAT (cm3) was assessed by computed tomography at the year 25 exam (43–55 yrs, n=1822). Results: Early adulthood PA levels were 15.2% lower in blacks compared to whites (p&lt;0.001) and 30.0% lower in women compared to men (p&lt;0.001); the lowest PA levels were observed in black women. Compared with the highest levels of PA, participants with moderate or lower PA during young adulthood exhibited higher VAT at middle age in linear regression models adjusted for covariates including year 25 BMI (Table 1). When stratified by race and sex, white men and women with higher PA levels exhibited lower VAT at middle age compared to white adults with moderate or lower PA; an association not observed in black men or women. Conclusions: White men and women engaging in higher PA levels at earlier ages may demonstrate lower visceral adiposity later in life, yet these findings suggest that PA may not be a solely effective approach at reducing/preventing cardiometabolic risk from excess visceral adiposity in black adults. Racial variations in the influence of young adulthood PA on visceral adiposity at middle age may reflect differential influences of PA, PA intensity, or other unmeasured risk factors (e.g., psychosocial stress) on adiposity distribution.
Lack of renal effects of fish oil administration in patients with advanced cirrhosis and impaired glomerular filtration
Authors: S Badalamenti
Journal: Hepatology (1997)

The treatment of renal failure in cirrhotic patients with ascites remains unsatisfactory. Recent studies have shown that the dietary supplementation with fish oil improves the renal function of normal subjects, as well as that of patients with renal failure of different etiologies. We have investigated the renal effects of a daily supplementation for 1 month of 12 g fish oil (27% C20:5 n-3 eicosapentanoic acid [EPA], and 23% C22:6 n-3 docosahexanoic acid [DHA]) in a prospective study of cirrhotic patients with ascites, nine with normal renal function (group 1) and eight with renal failure (glomerular filtration rate [GFR] < 60 mL/min, group 2). Compliance with the dietary regimen was confirmed by fatty acid chromatography that showed increased plasma concentration of EPA (from 1.5 ± 0.7% to 3.7 ± 0.8%, P = .024, in group 1; and from 0.53 ± 0.3% to 2.9 ± 0.8%, P = .03, in group 2) and of DHA (from 2.1 ± 0.4% to 3.4 ± 0.3%, P = .008, in group 1; and from 1.45 ± 0.5% to 3.8 ± 0.4%, P = .05, in group 2). At the end of the study, in patients from group 1, the glomerular filtration rate increased by 19% (from 94 ± 8 to 113 ± 13 mL/min, P = .039), and the urine flow increased by 39% (from 0.85 ± 0.14 to 1.12 ± 0.2 mL/min, P = .039), while no changes occurred in the renal function of patients from group 2. No changes were observed in the urinary excretion of prostaglandin (PG) E2 or of 6-keto prostaglandin-1-alpha (6-K-PGF1-alpha) nor in plasma renin activity (PRA) or the plasma concentration of aldosterone (PA) or antidiuretic hormone (ADH) in both groups. As far as undesirable effects of fish oils were considered, the mean arterial pressure (MAP) decreased in both groups (group 1: from 88.6 ± 2 to 85.3 ± 2 mm Hg, P = .015; group 2: from 88.2 ± 3 to 82.8 ± 3 mm Hg, P = .05), and bleeding time displayed a significant increase when patients were considered collectively (from 744 ± 89 to 872 ± 106 seconds, P = .0068). In conclusion, the administration of fish oil for 1 month was unable to improve renal function in cirrhotic patients with ascites and renal failure. The occurrence of undesirable effects, such as the reduction of arterial pressure and the prolongation of bleeding time, argues against the use of fish oils in these patients.
Reversible heart block in acute leukemia
Authors: L. C. Maguire
Journal: JAMA (1978)

INVOLVEMENT of the heart or pericardium in leukemia is a common finding in postmortem studies, with an incidence varying between 30% and 37%.<sup>1</sup>Despite this high frequency, little morbidity or mortality is usually produced. Pericarditis, cardiomegaly, congestive heart failure, or ECG changes develop only occasionally. The ECG changes, including tachycardia, ST-T wave, and voltage changes are usually of a nonspecific nature<sup>2-4</sup>and asymptomatic. Heart block has rarely been reported and is usually not symptomatic.<sup>4-7</sup>However, high-grade heart block may be fatal if untreated.<sup>5,6</sup>The cases reported by Blotner and Sosman<sup>1</sup>in 1944 and by Habel<sup>7</sup>in 1973 suggest that it may respond to radiotherapy. We report the case of an adult with erythroleukemia in whom symptomatic seconddegree heart block developed, which responded promptly to a single dose of radiation and ultimately had all evidence of conduction system disturbance resolve. <h3>Report of a Case</h3> A
Book Review Biological Symposia: A series of volumes devoted to current symposia in the field of biology . Edited by Jaques Cattell, Ph.D. Vol. III. Muscle. Edited by Wallace O. Fenn, Ph.D. 8°, cloth, 370 pp., with 15 tables and 82 figures. Lancaster, Pennsylvania: The Jaques Cattell Press, 1941. $3.50.
Journal: New England Journal of Medicine (1942)
A 14-GENE SIGNATURE ASSOCIATED TO CHOLESTEROL METABOLISM IDENTIFIES M1-LIKE TUMOR-INFILTRATING MACROPHAGES AND PREDICTS PATIENT SURVIVAL IN DIFFUSE LARGE B CELL LYMPHOMA
Authors: M. C. Vegliante, S. De Summa, M. Fabbri, G. Opinto, F. Melle, G. Motta, A. Gulino, G. Loseto, C. Minoia, S. Tommasi, A. Scattone, A. F. Zito, C. Agostinelli, U. Vitolo, A. Chiappella, A. Rambaldi, C. Tripodo, A. Guarini, A. Moschetta, S. Ciavarella, S. A. Pileri
Journal: HemaSphere (2019)
Tolnaftate Used in Treatment of Dermatomycoses
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Correction
Journal: Circulation Research (2009)

TRPC1 Associates With BK Ca Channel to Form a Signal Complex in Vascular Smooth Muscle Cells: Correction In the article that appears on page 670 of the March 13, 2009, issue, Figure 8 was published with errors.Incorrect secondary antibodies were used for immunostaining.The experiments are now repeated with corrected secondary antibodies (donkey anti-rabbit immunoglobulin G conjugated to Alexa Fluor 488 and donkey anti-goat immunoglobulin G conjugated to Alexa Fluor 546).The corrected Figure 8 is printed below.These corrections do not affect the conclusions presented in the article.
THE PROGRAMME OF THE ANNUAL MEETING.
Journal: JAMA (1889)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Old Masterpieces in Surgery. Being a Collection of Thoughts and Observations Engendered by a Perusal of Some of the Works of Our Forebears in Surgery Which Appeared in Serial Form in Surgery, Gynecology and Obstetrics During 1924 and 1925.
Journal: JAMA (1926)

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Virus-induced Airway Hyperresponsiveness: Role of Inflammatory Cells and Mediators
Authors: Gert Folkerts, Frans P. Nijkamp
Journal: American Journal of Respiratory and Critical Care Medicine (1995)

Viral respiratory infections induce airway hyperresponsiveness in asthmatic patients, in healthy persons, and in a number of animal species. In asthmatics the degree of airway hyperresponsiveness is associated with the severity of exacerbations. The respiratory tract of an asthmatic is inflamed, and these inflammatory cells might be involved in modulating airway responsiveness. In contrast, no data are available on the role of bronchoalveolar cells in the airways of “healthy” persons or asthmatic patients suffering a respiratory tract infection. Because of the lack of information on this issue, the present review has been written. A number of animal studies have now been performed suggesting the involvement of inflammatory cells during a viral respiratory infection. The changes in number and activity of bronchoalveolar cells after a viral infection have been compared with changes in airway morphology and the development of airway hyperresponsiveness. Based on these data we suggested, the following hypothesis: Viruses damage the epithelial layer of the respiratory tract and activate bronchoalveolar cells. Subsequently, a number of mediators are released that can stimulate metachromatic cells, which in turn release products that increase vascular permeability and attract inflammatory cells that might cause additional epithelial damage. Finally, the released mediators and the morphologic changes together result in airway obstruction and the development of hyperresponsiveness.
Temporal arteritis without pain
Authors: A. J. Barot
Journal: JAMA (1980)

TEMPORAL or cranial arteritis, also called giant cell arteritis because of histological features, is an inflammatory disorder that occurs primarily among the elderly. Characteristic symptoms include tenderness of the scalp, palpable superficial scalp or facial arteries, and headache, eye pain, or facial pain. Also frequently associated are fever, anorexia, arthralgia, and general malaise.<sup>1</sup>Headache<sup>2</sup>or, especially, facial pain are usually considered hallmark symptoms. Furthermore, the ESR is almost invariably elevated to a notable degree.<sup>3</sup>Symptoms and progression of the disease are usually easily and swiftly reversed with oral corticosteroid therapy.<sup>4</sup>In light of the treatable nature of the disease, it is unfortunate that signs and symptoms may be unrecognized for several months before a diagnosis is made. We report the case of an elderly man in whom diagnosis was initially doubted because of the absence of pain. <h3>Report of a Case</h3> A 70-year-old man in otherwise
Methanol poisoning
Authors: K. Closs
Journal: JAMA (1970)

A 63-year-old man consumed a nonidentified beverage 18 hours before hospitalization. His symptoms—headache, nausea, vomiting, abdominal pain, drowsiness, and marked dyspnea leading to deep coma—suggested methanol poisoning. Pupillary reaction was impaired, acidois was present, and the urine contained methanol, formic acid, and formaldehyde. Treatment with sodium bicarbonate, saline, and glucose-insulin was immediately instituted. Oliguria was treated with extracorporeal dialysis, and the patient recovered completely except for a thrombosis in the left leg.