tbuckley/cabot-search huggingface dataset:
Histopathology of the Peripheral and Central Nervous Systems
Journal: JAMA (1941)

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THE THIRD ANNUAL SESSION OF THE ASSOCIATION OF AMERICAN MEDICAL COLLEGES.
Journal: JAMA (1892)

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Correction
Journal: BMJ (1949)

ANY QUESTIONS?There is no purpose in discussing the details of differential diagnosis and treatment of these two widely different syndromes, but the questioner will find the information he requires in the papers cited.T.A.B. in Cheiropompholyx #?.-What are the rationale and method of administration of T.A .B. in thle treatment of cheiropompholyx ?A.-There is no rationale for the use of T.A.B. in pom-
AMA grams
Journal: JAMA (1970)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Nasal polps.
Authors: J Ballantyne
Journal: BMJ (1973)

Fashions in Infant Feeding SIR,-Your leading article (30 June, p. 727) summarized the dangers of feeding babies with milk containing too high a solute con- tent.It was stated that severe hypernatrae- mic dehydration may result from failure to follow the manufacturer's instructions.The method of making up a day's milk feeds (say 32 fl.oz. (900m)) using separate accurately measured single scoops is laborious and timeconsuming, and only the most meticulous mother is likely to produce regularly the de- sired concentration.I would suggest that a 4-unit scoop be also supplied with milk powders; or that the powder be supplied in sachets each containing four scoopfuls.I would also like to report that a popular brand of baby cereal sold widely in child welfare centres has the following instructions on the packets:"-is very effective when added to baby's last feed at night.According to age, up to one heaped teaspoonful for every 2 oz. of boiled water used in making the bottle feed will help baby and mother to have an unbroken nights' sleep."Un- fortunately, many mothers deduce that it may be helpful for peaceful days too, and not infrequently I have found that the extra solute is also being added to one or two feeds during the day.-Iam, etc.,
Laryngeal Epilepsy.
Authors: John Keriher
Journal: JAMA (1894)

Chicago, Ill., Nov. 16, 1894. <h3>To the Editor:</h3> —In the society proceedings of the Chicago Academy of Medicine, as published in theJournalof November 10, on page 727, there appears an article by Dr. Edward T. Dickerman on "Laryngologic Relations of Epilepsy." In this article the Doctor states that "up to date, twenty-one cases have been reported," etc. I wish to state that the Doctor may be able to add one to the list if he will look up theJournalof June 3, 1893 page 604, and find "A Case of Laryngeal Epilepsy." Respectfully,
Books Received
Journal: JAMA (1926)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The medical care cost of human immunodeficiency virus-infected children in Harlem
Authors: J. D. Hegarty
Journal: JAMA (1988)

To estimate the cost of hospital care for children infected with the human immunodeficiency virus (n = 37) at Harlem Hospital Center, New York, a cost-based inventory of medical resource consumption was developed. Six thousand thirty-five inpatient days were audited by retrospective chart review. The total cost of care between 1981 and 1986 was $3 362 597. Average lifetime costs were $90 347 per child. One third of the total inpatient days and over 20% of the cost resulted from social rather than medical factors. Per diem costs were highest for children with opportunistic infections ($705) and lowest for homeless "boarder babies" ($466). Boarder babies had a mean length of stay nearly four times longer than those with homes (339 days vs 89 days). The primary predictors of length of stay were maternal intravenous drug use and boarder baby status, regardless of medical need. The unique needs of human immunodeficiency virus—infected children require innovative medical, social, and financial solutions. (<i>JAMA</i>1988;260:1901-1905)
Die Konstitution als Faktor in der Pathologie und Therapie der Syphilis.
Journal: JAMA (1925)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Malar bone pressure test for evaluation of headache
Authors: M. Scott
Journal: JAMA (1970)

<h3>To the Editor.—</h3> Headache is a common complaint and is often caused by definite cranial or systemic disease. Occasionally the patient is suspected of exaggerating this complaint or has conversion symptoms due to anxiety, and the physician desires an objective method of evaluating the head pain. Some years ago I described a test which I had found useful for such an evaluation. However, it was published in a specialty journal, and I believe escaped the attention of many physicians who are frequently confronted with this diagnostic problem.<sup>1</sup>Time has proven the usefulness of this test and I believe that it merits another publication. I found this simple procedure helpful in differentiating true headache from that of the "functional type." It has been tried in many patients in whom the headaches have been caused by such conditions as brain tumor, cerebral hemorrhage, migraine, trauma, hypertension, atypical vascular neuralgia, and anxiety
Angiogenesis
Authors: Judah Folkman
Journal: Annual Review of Medicine (2006)

Angiogenesis inhibitors for the treatment of cancer have now been approved by the Food and Drug Administration in the United States, and in 28 other countries including China. Clinical application of this new class of drugs is informed by certain principles from angiogenesis research. Oncogenic mutations initiate tumorigenesis, but angiogenesis is necessary for expansion of tumor mass. Two angiogenesis inhibitors have been developed that have a broad spectrum of anticancer activity, yet virtually no side effects. Endogenous angiogenesis inhibitors act as tumor suppressor proteins. The angiogenic response in vivo is based on the genetic background of the host. Several types of angiogenesis inhibitors reveal a biphasic, U-shaped curve of efficacy. "Antiangiogenic chemotherapy" is a novel approach to the treatment of drug resistance.
Erratum
Journal: BMJ (1893)

A PERPLEXING CASE.'A MEMBER !writes:I shall feel obliged if some or your readers will give their opinlon of the following case.I have been consulted about the wifeof a professional gentleman of good standing and in comfortable circamstances.She had two of a family-one aged 3 years, the other 6 months.She does not nurse.She imagines she is getting very thin, and insists on taking tonics and fat-producing foods.No disease can
Pediatrics, Springfield, Ill
Journal: JAMA (1964)

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The Importance of the Baby-Friendly Hospital Initiative
Authors: Heather M. Wasser, M. Jane Heinig, Kristin P. Tully
Journal: JAMA Pediatrics (2017)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Pediatrics HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Pediatrics journal
Hyperuricemia, gout, and the executive suite
Authors: J. L. Katz
Journal: JAMA (1973)

Eight pairs of adult brothers (in one instance, actually first cousins raised together), all with family histories of gout and therefore likely to have hyperuricemia, were examined for possible correlations between achievement-related variables and relative serum uric acid (SUA) levels within each pair. Manifest achievement, achievement orientation, and achievement drive did not reliably predict which brother in each pair possessed the higher SUA level. However, when the variable of obesitydietary content was employed, significant predictive success was attained. Obesity did not correlate with achievement drive. However, the tonic and phasic eating histories of our subjects do suggest a possible explanation for the previous reports of a correlation between SUA level and such achievement-related variables.
Editorial Board
Authors: Joanna Schaffhausen, Milka Kostic, Basil Nyaku, Ria Otten, Patrick Scheffmann, S Amara, N Birdsall, N Bowery, J Crawley, A Cuello, B Fredholm, L Hunyady, T Kenakin, M Mishina, W Moolenaar, C Page, Uk Ruffolo, R Summers, Australia Tanaka, Japan Watson, Vivian Ward
Journal: Trends in Pharmacological Sciences (2011)
MECHANICAL PRESCRIBING IN HOSPITALS AND DISPENSARIES.
Journal: JAMA (1907)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Varied Effects of Atypical Neuroleptics on P50 Auditory Gating in Schizophrenia Patients
Authors: L. E. Adler
Journal: American Journal of Psychiatry (2004)

OBJECTIVE: Sensory gating deficits found in schizophrenia can be assessed by using a paired auditory stimulus paradigm to measure auditory evoked response. The ratio of the P50 response amplitude of the second or test stimulus to that of the first or conditioning stimulus is expressed as a percentage. Normal subjects generally suppress the second response and typically have ratios of less than 40%. Subjects with schizophrenia and half their first-degree relatives have deficits in sensory gating, with P50 ratios that are generally greater than 50%. Treatment with typical neuroleptics does not reverse this deficit. However, previous studies have shown that treatment with clozapine, an atypical neuroleptic, ameliorates this deficit in clinically responsive patients. This study sought to determine whether other atypical neuroleptics improve P50 ratios. METHOD: P50 evoked potential recordings were obtained from 132 patients with schizophrenia and 177 healthy comparison subjects. Eighty-eight patients were being treated with atypical neuroleptics (clozapine [N=26], olanzapine [N=31], risperidone [N=22], and quetiapine [N=9]). Thirty-four patients were taking typical neuroleptics, and 10 were unmedicated. RESULTS: Healthy subjects exhibited P50 suppression that was significantly better than the schizophrenia patients receiving typical neuroleptics (mean=19.8% [SD=21.0%] versus 110.1% [SD=87.9%]). Patients receiving atypical neuroleptics had a mean P50 ratio that fell between these two means (mean=70.4%, SD=53.7%). When patients treated with different atypical neuroleptics were compared, only the clozapine group had mean P50 ratios that were in the normal range. All other groups exhibited auditory P50 response inhibition that was significantly poorer than that of the healthy subjects. CONCLUSIONS: Improvement in P50 gating appears to be greatest in patients treated with clozapine.
Late Versus Early Testing of HIV—16 Sites, United States, 2000-2003
Journal: JAMA (2003)

Knowledge of human immunodeficiency virus (HIV) serostatus has been an important element of HIV-prevention and -treatment efforts. In 2000, among the estimated 850,000-950,000 persons living with HIV in the United States, approximately one fourth (180,000-280,000) were unaware that they were HIV infected. In addition, many persons with HIV are tested late in the course of infection, usually as a result of illness. During 1994-1999, among persons who had HIV diagnosed, 43% were tested late in the infection (i.e., had acquired immunodeficiency syndrome [AIDS] diagnosed within one year of HIV diagnosis). Late testing results in missed opportunities for prevention and treatment of HIV. To characterize HIV-testing patterns among HIV-infected persons, CDC analyzed data from a multisite interview project. During May 2000-February 2003, persons at 16 U.S. sites who were tested early in the course of HIV disease (early testers) were compared with persons who were tested late in the course of HIV disease (late testers). This report summarizes the results of the analysis, which indicate that late testers were more likely than early testers to be black or Hispanic, less educated, and exposed to HIV through heterosexual contact. Reducing the incidence of both new infections and HIV-associated morbidity and mortality will require earlier testing and improved access to prevention and care services for persons infected with HIV. A new CDC initiative, "Advancing HIV Prevention: New Strategies for a Changing Epidemic," is aimed at reducing barriers to early diagnosis of HIV infection and increasing access to quality medical care, treatment, and ongoing prevention services.
81MO Clinical experience of a personalized and tumour-informed circulating tumour DNA assay for minimal residual disease detection in oligometastatic colorectal cancer patients
Authors: S.A. Cohen, N. Hook, S. Krinshpun, L. Westbrook, K. Loranger, J. Wallace, S. Sharma, A. Aleshin, P. Billings
Journal: Annals of Oncology (2020)
Oxidative Stress Induces NF-κB Nuclear Translocation Without Degradation of IκBα
Authors: Timothy G. Canty, Edward M. Boyle, Angie Farr, Elizabeth N. Morgan, Edward D. Verrier, Timothy H. Pohlman
Journal: Circulation (1999)

Background— Rel/NF-κB, an oxidative stress–responsive transcription factor, participates transiently in the control of gene expression. The cellular mechanisms that mediate NF-κB activation during ischemia (and during reperfusion in the course of treating ischemia) are not known. Methods and Results— To investigate the NF-κB activation induced during oxidative stress, we examined human cardiac tissue obtained during surgical procedures requiring cardiopulmonary bypass. In vitro, we examined human umbilical vein endothelial cells (HUVECs) exposed to hypoxia, reoxygenation after hypoxia, or a reactive oxygen intermediate (H 2 O 2 ). Electrophoretic mobility shift assays performed on right atrial tissue revealed prominent NF-κB activation after hearts had been exposed to ischemia and reperfusion. The assays also showed that NF-κB activation was observed in hypoxic HUVECs after reoxygenation and in cultures treated with H 2 O 2 (500 μmol/L). Pervanadate (200 μmol/L) also induced marked NF-κB activation in HUVECs, indicating that H 2 O 2 -induced NF-κB activation is potentiated by the inhibition of tyrosine phosphatases. Western blotting of cytoplasmic IκBα demonstrated that NF-κB activation induced by oxidative stress was not associated with IκBα degradation. In contrast, tumor necrosis factor-α–induced NF-κB activation occurred in concert with degradation of IκBα. Inhibition of IκBα degradation with a proteasome inhibitor, MG-115, blocked NF-κB activation induced by tumor necrosis factor-α; however, MG-115 had no effect on NF-κB activation during oxidative stress. Conclusions— This study demonstrated a stimulus-specific mechanism of NF-κB activation in endothelial cells that acts independently of IκBα degradation and may require tyrosine phosphorylation.