tbuckley/cabot-search huggingface dataset:
US Medical School Finances
Authors: Jack Y. Krakower
Journal: JAMA (1993)

THIS review of medical school finances reports revenue and expenditures for all 126 fully accredited US medical schools for fiscal year 1991-1992. For the preceding 10 years, from 1981-1982 to 1991-1992, we examine changes in the following areas: federal research support, state support, medical service, tuition and fees, scholarships and loans, and medical school finances as these relate to the number of faculty, house staff, and medical students. <h3>DATA SOURCES AND CHARACTERISTICS</h3> Data were derived from medical schools' responses to the annual questionnaire of the Liaison Committee on Medical Education. For financial reporting, the Liaison Committee on Medical Education defines a medical school in terms of its faculty activities, which include research, instruction, and patient care. The questionnaire requires schools to report all revenues and expenditures that support full-time faculty and their activities, whether or not these are recorded in medical school accounts. This definition makes the finances of medical
Effects of hepatitis B virus, alcohol drinking, cigarette smoking and familial tendency on hepatocellular carcinoma
Authors: C Chen
Journal: Hepatology (1991)

Independent and interactive effects related to the development of hepatocellular carcinoma were assessed using a community-based case-control study for hepatitis B virus, habitual alcohol drinking, cigarette smoking, peanut consumption and history of hepatocellular carcinoma among the immediate family. All 200 male newly diagnosed hepatocellular carcinoma patients were recruited consecutively through the period of study as the case group from two teaching medical centers in northern and southern Taiwan. Healthy community residents matched one-to-one with cases on age, sex, ethnic group and residential area were selected as the control group. The carrier status of HBsAg and HBeAg was determined by blind radioimmunoassays, and other risk factors were obtained through standardized interviews according to a structured questionnaire. Conditional logistic regression analysis showed a significant association between hepatocellular carcinoma and the carrier status of HBsAg and HBeAg with an odds ratio of 16.7 and 56.5, respectively, for carriers of HBsAg alone and for carriers of both HBsAg and HBeAg. There was a dose-response relationship between cigarette smoking and hepatocellular carcinoma with an odds ratio of 1.1, 1.5 and 2.6, respectively, for those who smoked 1 to 10, 11 to 20 and more than 20 cigarettes a day. A significant association with hepatocellular carcinoma was also observed for the habitual alcohol consumer with an odds ratio of 3.4. Those whose immediate family had a history of hepatocellular carcinoma were more likely to have the disease develop, with an odds ratio of 4.6. However, the frequency of peanut consumption was not significantly associated with hepatocellular carcinoma. Whereas the modification of age was not statistically significant, hepatocellular carcinomaassociated risk factors were multiplicatively independent under the conditional logistic model. (HEPATOLOGY 1991;13:398–406.)
Cholecystokinin Cholangiography
Authors: Franz Goldstein
Journal: JAMA (1974)

<h3>To the Editor.—</h3> While numerous reasons could be listed for the differences in results, including differences in patient selection and the astoundingly large number of patients found suitable for study by Dunn's group over such a short period of time, one overriding difference makes all such comparisons irrelevant. The study deals with a response of the gallbladder to cholecystokinin different from those responses with which comparisons are made. A glance at the abnormal radiologic gallbladder response after cholecystokinin illustrated in Dunn's paper, and their description of the rapid (45-second) intravenous injection of cholecystokinin, make it apparent that these authors accurately reproduced the spasm of the gallbladder infundibulum first described by Torsoli et al<sup>1</sup>in 1961 with 30-second injections. Torsoli et al carefully differentiated between gallbladder contraction consistently obtained with rapid (30-second) cholecystokinin injections and gallbladder emptying obtained with slow (three-minute) injections. We and our colleagues<sup>2,3</sup>have repeatedly emphasized
Health Services
Journal: JAMA (2001)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Recurrent aseptic meningitis in an elderly man. Unusual prodrome of systemic lupus erythematosus
Authors: P. F. Finelli
Journal: JAMA (1976)

NONINFECTIOUS meningeal involvement in systemic lupus erythematosus (SLE) occurs in approximately 8% of cases and is almost always associated with diffuse neurological deficits. The only well-documented case of aseptic meningitis without other neurologic or psychiatric symptoms was that of a patient with known SLE in whom the VDRL test, fluorescent treponemal antibody absorption test, antinuclear antibody test, and lupus erythematosus preparation were positive.<sup>1</sup>Aseptic meningitis as a prodromal manifestation of SLE in a seronegative patient has not been described, to our knowledge. We report such a case. <h3>Report of a Case</h3> A 61-year-old man was admitted to David Grant USAF Medical Center in July 1974 with a two-month history of headaches, generalized myalgia, fever, nausea, anorexia, and a weight loss of 6.8 kg (15 lb). Physical examination results were entirely within normal limits. Laboratory tests showed a hematocrit reading of 35.8%, white blood cell (WBC) counts of 3,200 and
Volume Contents
Authors: C.-Y Dai, W.-L Chuang, C.-K Ho, M.-Y Hsieh, J.-F Huang, L.-P Lee, N.-J Hou, Z.-Y Lin, S.-C Chen, L.-Y Wang, J.-F Tsai, W.-Y Chang, Y Kawashita, C Guha, R Moitra, X Wang, I Fox, J Roy-Chowdhury, N Roy, K Pachkoria, M Lucena, E Crespo, F Ruiz-Cabello, S Lopez-Ortega, M Fernandez, M Romero-Gomez, A Madrazo, J Dura, A De Dios, Y Borraz, A Kong, K Choi, C Cockram, M Chan, R Ozaki, G Wong, G Ko, W So, P Tong, C Lam, J Lau, F Chow, J Chan, D Barisani, S Pelucchi, R Mariani, S Galimberti, P Trombini, D Fumagalli, R Meneveri, E Nemeth, T Ganz, H Barth, E Robinet
Journal: Journal of Hepatology (2008)
The International Factory Clinic for the Treatment by Sun and Work of Indigent Cases of "Surgical" Tuberculosis.
Journal: JAMA (1930)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Telenursing
Authors: Lisa Wentworth Smith
Journal: JAMA (2012)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
APPROVED RESIDENCIES AND FELLOWSHIPS
Journal: JAMA (1949)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Atlanta Meeting.
Authors: None D. L.
Journal: JAMA (1895)

Rockford, Ill., Dec. 6,1895. <h3>To the Editor:</h3> —Permit me to suggest that the Transportation Committee of theAssociationsoon begin considering and agitating the question of railway rates to the meeting at Atlanta next May. It is not sufficient that transportation be secured for the editors of medical journals who have secured a square or half-page of advertising from railways and connecting lines to Atlanta. These journals may "whoop up" the meeting, but the rank and file, the bone and sinew of the profession, will not get there unless some generous concessions are made by the transportation companies. Would it not be a good plan to secure a pledge in advance from the city or cities bidding for theAssociationto guarantee a cheap railway rate? The G. A. R., the political and the secret society conventions do this, or begin work early to secure minimum rates. The National Teachers'
Karyotoon No 11
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstracts
Journal: Annals of the Rheumatic Diseases (1957)

It has frequently been suggested that those persons who are susceptible to rheumatic fever have an intrinsic factor unduly sensitizing them to Group-A streptococcal infections of the upper respiratory tract.At the Canadian Red Cross Hospital, Taplow, Buckinghamshire, they therefore investigated the relation between the incidence of rheumatic fever and the presence of blood-group antigens (A, B, H, and Lewis) in the saliva and, presumably, the mucous secretions of the throat.Saliva obtained was prepared and titrated against Lewisa antiserum obtained from immunized rabbits, a heavy white precipitate after one hour's incubation indicating a positive reaction.The reliability of the test was con- firmed on saliva from healthy people of known Lewis blood group.The precipitin test for Lewisa substance and the haemagglutination-inhibition titration test for A and B substances were also carried out with saliva from 115 healthy subjects.Analysis of the results and those of previous workers showed that 3-75 per cent. of patients did not secrete A, B, H, or Lewis antigen.Altogether 450 patients with rheumatic fever, 253 with rheumatoid arthritis, and 460 healthy school-children were studied, the precipitin and/or haemagglutinationinhibition tests being carried out in the cases of rheumatic fever and the precipitin test only in the other two groups.Lewisa-positive results were obtained in 100 (21-7 per cent.) of the healthy controls, fifty (19 8 per cent.) of the patients with rheumatoid arthritis, and 124 (27-6 per cent.) of those with rheumatic fever.When allowance was made for the 3-75 per cent.total non-secretors, the incidence of Lewis-antigen secretors in the healthy controls was 22-6 per cent., in the patients with rheuma- toid arthritis 20-6 per cent., and in those with rheumatic fever 28-7 per cent.This difference was significant at the 5 per cent.level.As secretor status is genetically determined, the authors state that these figures support the view that there is an hereditary factor in rheumatic fever.They postulate the possibility of a blood-group linked haptenic material being present in the throat secretions during a strepto- coccal infection before the onset of rheumatic fever, the haptene being absorbed on the bacteria and becoming completely antigenic.M. Kendal.Hyaluronidase Activity of the Serum in Rheumatic Fever.
Commentaire de travail de M. Al-Haddad et al., pp. 127
Journal: Endoscopy (2010)

See also: Safety and efficacy of cytology brushings versus standard fine-needle aspiration in evaluating cystic pancreatic lesions: a controlled studyEndoscopy 2010; 42(02): 127-132DOI: 10.1055/s-0029-1215351
CATARRHAL LARYNGITIS.
Authors: HENRY R. SLACK
Journal: JAMA (1899)

Fortunate indeed are the parents who have reared children, and are unacquainted with croup. Few diseases of childhood produce such distressing and alarming symptoms, and at the same time are so seldom fatal, as spasmodic croup. I venture the assertion that nearly all have time and again had the following experience: shortly after midnight we are aroused from our pleasant slumbers by the violent ringing of the door-bell; and, on answering it, we find a half-dressed, badly frightened father. "Hurry, Doctor! My child has the croup, and I fear he will be dead before you can reach him—hurry!" We in a few minutes reach the bedside, where all is consternation and confusion. The little four-yearold is on the mother's lap, breathing heavily, face congested and voice husky, with an occasional croupy cough that sends terror to the parents' hearts. The grandmother is busy mixing alum and honey, vinegar, salt and
Suppressive CpG
Authors: Heather L. Van Epps
Journal: The Journal of Experimental Medicine (2005)

Constipation killsCellular constipation can be deadly, according to a study on page 1587.Wang and colleagues show that cells get clogged with aborted secretory cargo when they lack an enzyme that helps form vesicles.Deletion of this enzyme proved lethal in mice, halting brain, bone and vascular development.The enzyme in question is a protein tyrosine phosphatase (PTP) called MEG2.MEG2 binds lipids and resides on intracellular vesicle membranes, where it clips phosphate residues from the fusion protein NSF.Once dephosphorylated, NSF initiates homotypic fusion between immature secretory vesicles, a critical step in protein secretion.Knocking out MEG2, the team found, prevented T cells (isolated from chimeric mice) from secreting the autocrine growth factor interleukin-2, stunting T cell proliferation in response to stimulation.Electron micrographs of the deficient T cells revealed that the cells lacked mature secretory vesicles and were clogged with the dense remains of fusion-incompetent vesicles.Platelets that lacked MEG2 were also dysfunctional, failing to aggregate when exposed to the clotting factor thrombin.But the MEG2 defect spared neutrophils and macrophages, although these cells rely on the same cellular machinery for vesicle release.Cell type-specific PTPs might compensate for MEG2's absence in neutrophils and macrophages.Besides looking for these PTPs, the group is also investigating the mechanism behind the developmental defects in the MEG2-deficient mice, which they suspect result from an inability to produce growth factors that direct the migration and differentiation of progenitor cells.
POSSIBLE COMPLICATIONS OF THE STEINACH OPERATION
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 171: Promoter Negative Elongation Factor a (NelfA) Occupancy Required for Gene Transcription in Heart During Hypertrophy
Authors: Elena Severinova, Zhi Yang, Maha Abdellatif, Danish H Sayed
Journal: Circulation Research (2017)

Adaptive change in gene expression is one of the earliest responses of heart to hypertrophy. Gene transcription is tightly regulated by systematic recruitment of factors including positive and negative elongation complexes of RNA Pol II. Recently we embarked on the task of deconstructing the transcriptional machinery in the heart, by examining Pol II and TFIIB dynamics across the genome in sham and hypertrophied hearts. In this study, we continue examining the active transcriptional code by measuring occupancy of two interdependent factors that belong to positive (PTEFb) and negative (NELF) elongation complexes, Cdk9 and NelfA, respectively. Studies in non-cardiac cells have implicated these two factors in the regulation of promoter (prom) clearance of pol II, where Cdk9 mediated phosphorylation of NelfA results in its release from paused pol II and initiation of productive elongation. As expected, we observed increase Cdk9 (&gt;1.5) association with proms in 59.7% of expressed genes (8257 of 13816), while 6% show decrease in prom Cdk9 (&lt;0.75) in TAC vs. sham hearts. In contrast to previous reports, we did not see any correlation between Cdk9 and NelfA occupancy, where 93.2% and 68% of genes did not show change in NelfA with increased or decreased Cdk9 levels in TAC hearts, respectively. Interestingly, highest enrichment of NelfA (av. density 53.5) was observed on genes regulated by prom clearance of pol II (av. prom den 9.5 vs. 7.4; av. Ingene den 3.0 vs. 3.6, sham vs. TAC; housekeeping genes) with no change in NelfA (89.8% of genes). On other hand, 3.3% of genes showed increase in NelfA (av. den 4.6 vs. 8.4, sham vs. TAC), along with increase in pol II recruitment (av. prom den 3.3 vs. 4.04; av. ingene den 1.8 vs. 2.4, sham vs. TAC; cytoskeletal, cell cycle genes). We confirmed increase in mRNA abundance of these genes, (eg. Acta 1) in TAC vs. sham hearts. Intriguingly, genes that were associated with reduced NelfA (av. den 21.7 vs. 14.8, sham vs. TAC) were mostly cardiac specific genes (e.g. cardiac muscle contraction), which show increase in pol II, but no change in mRNA levels with TAC (eg. Actc). While we are investigating the role of NelfA in heart, ChIP- Seq data suggest that NelfA might be required for productive elongation and increase in global gene expression during hypertrophy
Hernia
Journal: JAMA (1941)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal