tbuckley/cabot-search huggingface dataset:
Everest Nails
Authors: Stuart J. Hutchison, Smita Amin
Journal: New England Journal of Medicine (1997)

To the Editor: In their review of prosthetic heart valves, Vongpatanasin et al. (Aug.8 issue) 1 propose guidelines for anticoagulant therapy after valve implantation without citing references to support them.The authors make the surprising recommendation that patients with mechanical valves receive anticoagulant therapy "preferably within 6 to 12 hours" after valve implantation.If this recommendation refers to warfarin, how is it administered?If it refers to heparin, then the patient is at risk for bleeding during this period, given the fact that platelets are nonfunctioning after weaning from cardiopulmonary bypass.It is unclear how best to deal with the partial-thromboplastin time during this period; also unclear are the implications for the removal of chest tubes.The authors go on to suggest that single-leaflet valves require an international normalized ratio (INR) between 3.0 and 3.9, and bileaflet-tilting-disk valves require an INR between 2.5 and 2.9, again citing no references.The current guidelines are for an INR of 2.0 for aortic valves and an INR of 2.5 to 3.0 for mitral valves. 2 These recommendations are for patients at low risk for systemic embolism.I believe it is important for the authors to address these issues in order to justify their recommendations.
Ergebnisse der medizinischen Strahlenforschung: (Röntgendiagnostik. Röntgen-, Radium- und Lichttherapie).
Journal: JAMA (1928)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Book Review Homicide Investigation: Practical information for coroners, police officers and other investigators. By LeMoyne Snyder, M.D. With chapters by Captain Harold Mulbar, Charles M. Wilson and C. W. Muehlberger. 8°, cloth, 287 pp., with 116 illustrations. Springfield, Illinois: Charles C Thomas, 1944. $5.00.
Journal: New England Journal of Medicine (1945)
Incorrect Date
Authors: Yngvild Olsen, Joshua Sharfstein
Journal: JAMA (2014)

In Reply Dr Stoddard notes that our Viewpoint on the stigma associated with the treatment of opioid use disorder did not discuss naltrexone.In 2010, the US Food and Drug Administration approved the extended-release formulation of naltrexone for relapse prevention of opioid use disorder based on evidence of efficacy against placebo.The omission in our Viewpoint was intentional.Our goal was to confront the common, inaccurate, and dangerous assertion that long-term therapy with methadone or buprenorphine (both agonist medications) is merely substituting one addiction for another.This misconception inhibits physicians from providing and patients from seeking needed, effective, and compassionate care.As an antagonist medication usually used for less than 6 months, naltrexone does not face the same degree of misunderstanding.Compared with the decades of scientific evidence supporting the safety and effectiveness of methadone and buprenorphine, there is substantially less experience and data associated with extended-release naltrexone.A few studies 1-3 suggest that the efficacy of naltrexone is no better and in some cases inferior to either agonist treatment.More definitive research is under way.There are many reasons physicians and patients might choose one approved therapy over another.Stigma should not be one of them.
Scientists develop more sensitive grading system for prostate cancer
Journal: BMJ (2002)

26 pilgrims carrying the W135 clone (all from different households), six (23%) transmitted this strain to seven contacts, of whom two were from the same household.The acquisition rate of the W135 clone in contacts of returning carriers of the same strain was 13% (seven out of 54 contacts). CommentsA high acquisition rate of a single clone of W135 N meningitidis occurred during the 2001 Hajj pilgrimage.Many countries currently give bivalent meningococcal vaccine (covering A and C) to Hajj pilgrims.Vaccination with the quadrivalent meningococcal vaccine (also covering W135) should become mandatory for all Hajj pilgrims and be considered for their household contacts.Transmission of this clone from vaccinated Hajj returnees to their unvaccinated household contacts was substantial, putting contacts at particular risk of developing invasive disease.Our findings support a policy of administering antibiotics to pilgrims before their return to their countries of origin to eradicate carriage and thereby protect household contacts.We thank Fatimah Karim and Anushia Panchalingham for taking swabs, Bernard Peperstraete for logistical help, Sindhu Ravindran for performing pulsed field gel electrophoresis, and Gamini Kumarsinghe for providing some of the meningococcal isolates of clinical cases.We also thank all the pilgrims and their contacts for participating in this study.Contributors: AW-S had the idea for the study and was responsible for study design and for collection, analysis, and interpretation of data.TMSB was responsible for the meningococcal cultures, serogrouping, and pulsed field gel electrophoresis.AE was responsible for data entry and analysis.
Contempo '92
Authors: Jody W. Zylke
Journal: JAMA (1992)

A coin in a fountain. A rub of a lamp. A wish on a star. Only the most cynical among us refrain from dreaming of wishes come true. And even if our wishes are not granted, the act of defining hopes and dreams may begin the actual work of fulfilling them. This year, we gave our Contempo authors a chance to make a wish—three, in fact—that, if granted, would change medicine in the United States today. Many responded with wishes that were far reaching but not unrealistic. They tended to focus on political, social, and practice issues rather than clinical ones. No one, for example, wished for cures for cancer. A few hoped for an HIV vaccine; this was the only specific scientific advance on the wish lists. No one explicitly wished for billions of dollars for medical care or research. By far the most frequently mentioned wish was for
An Examination of Certain Recently Reported Phenomena in Connection with Hystero-Epilepsy and Cerebral Anaesthesia
Authors: G. Sigerson
Journal: BMJ (1879)

4. 7T7e Exspei-inzctnal Investigationz.-Theproceedings of a commis- sion appointed by so distinguished a body as the Societe de Biologie of Paris, to whom the methods and results were duly reported, must be assumed to have been guided by strict principles of scientific research.Sufficient evidence of care and forethought will, in fact, be found in its records to show explicitly what might well be taken for granted, that no ordinary precautions were omitted; whilst many unusual tests were adopted, in order to arrive at correct conclusions.It is possible, of course, to devise other examinations; but, if the means employed be sound and complete enough to justify the conclusions drawn, the Com- mission must be accorded all credit due for a duty well performed.The liability to errors of omission, to which all men are subject, is reduced to its least expression where the work done is submitted to the scrutiny of many experienced and independent observers not prepossessed in its favour, nor careless of testing its accuracy.a. Safegztai-rd against Error.-Knowing the characteristics of the hysterical temperament, and remembering that they were appointed to decide upon alleged facts, the Commissioners were doubly vigilant.As a matter of course, they refrained from anything which should intimate to the patients what they thought likely or unlikely to occur; and,
Juvenile myelomonocytic leukemia (JMML) with the hematologic phenotype of severe β thalassemia
Authors: George R. Honig, Carlos R. Suarez, Loyda N. Vida, Shi‐Jiang Lu, Edison T. Liu
Journal: American Journal of Hematology (1998)

A 3-year-old Filipino-American child with recurrent fever, splenomegaly, anemia, and thrombocytopenia, was found to have a hemoglobin F level of 76.9%. His reticulocyte count was elevated (4.3%), and erythroblasts were present in his peripheral blood. The child's erythrocytes were microcytic (MCV 66.9 fl) but his serum ferritin level was normal. His bone marrow at initial presentation demonstrated normal cellularity without an increase in blast cells. The disease progressed with worsening anemia, leukocytosis, and thrombocytopenia, with increased blasts in his marrow and the appearance of a mediastinal mass. His liver, spleen, and lymph nodes were found to be infiltrated with myeloblasts, supporting a diagnosis of juvenile myelomonocytic leukemia (JMML). Analysis of the child's Hb F showed a Gγ/Aγ ratio of 2.2, which was within the characteristic range for JMML. A globin synthesis study using blood reticulocytes showed an α/non-α globin synthesis ratio of 2.24, typical of severe homozygous β thalassemia. Southern blot analysis of blood-leukocyte DNA from the patient and his parents demonstrated no apparent abnormality in the β-globin gene promoter or coding regions. The elevated level of Hb F in this child with JMML appeared to be part of an acquired Cooley's anemia-like hematologic phenotype. Am. J. Hematol. 58:67–71, 1998. © 1998 Wiley-Liss, Inc.
MAY A PHYSICIAN PREPARE HIS OWN DEATH CERTIFICATE?
Journal: JAMA (1995)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Presse Médicale, Paris
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
International Comments
Journal: JAMA (1969)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Factors Related to Cholesterol Screening, Cholesterol Level Awareness—United States, 1989
Journal: JAMA (1990)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Phenmetrazine psychosis.
Authors: E. Negulici, D. Christodorescu
Journal: BMJ (1968)

Certainly the general practitioner of the future has a proper part to play in an inte- grated maternity service, accepting with all other participants, including the consultant, a proper measure of responsibility for the aspect of the service that he is best trained and qualified to undertake.An awareness of individual responsibility and limitation should remove completely any thought of "loss of face."Further education of the patient seems to me to be a necessary part of the responsibility of us all.-Iam, etc.,
Eczema in Infancy and Childhood
Authors: Lewis Webb Hill
Journal: New England Journal of Medicine (1950)

THE following discussion of the literature of the past four years concerns several aspects of eczema in infancy and childhood: pathogenesis, general considerations, antihistaminic drugs, milk-free diets, unsaturated fatty acids, treatment of secondary infection, bacitracin, fungi, scabies, Kaposi's varicelliform eruption and eczema vaccinatum, nummular eczema, seasonal eczema due to pollen, blood protein depletion and hospital morbidity of eczematous infants.PathogenesisAtopic dermatitis comprises at least 75 per cent of the "eczema" of infancy and childhood, and in spite of much study the mechanism by which it is produced is still obscure. Although most patients with this disorder give multiple positive . . .
March 14, 2001
Journal: JAMA (2001)

Harold A. Sackeim, PhD; Roger F. Haskett, MD; Benoit H. Mulsant, MD; Michael E. Thase, MD; J. John Mann, MD; Helen M. Pettinati, PhD; Robert M. Greenberg, MD; Raymond R. Crowe, MD; Thomas B. Cooper, MA; Joan Prudic, MD
Varicella Ulcer of Cornea.
Journal: JAMA (1900)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A history lesson: hepatitis is not always what it seems
Authors: G. M. Zucker
Journal: JAMA (1982)

Two unusual hepatic presentations of otherwise common infectious diseases are reported in this issue ofThe Journal(pp 1999 and 2000). They illustrate that while viral A, B, and non-A, non-B acute hepatitis are ubiquitous, there are other infectious agents associated with hepatitis. The clinician must therefore consider other diagnostic possibilities among different age groups. In the neonate, cytomegalic inclusion-virus is a major cause of fetal and infant morbidity, followed by rubella (congenital or acquired) and herpes simplex (type 2 more than type 1).<sup>1</sup>Hepatitis seen with these viral illnesses is usually associated with other physical findings that may aid in their diagnosis. The presence of associated heart disease, pneumonitis, retinopathy, bleeding diathesis, or skin changes may be important clues to the nature of the viral illness. When acute hepatitis alone is present in the neonate, and viral isolation and serological findings are negative, metabolic or hereditary causes should
Underrecognition of Dementia by Caregivers Cuts Across Cultures
Authors: Mark R. Somerfield
Journal: JAMA (1997)

<h3>To the Editor.</h3> —The article by Dr Ross and colleagues<sup>1</sup>provides much-needed empirical evidence on the frequency with which family informants fail to recognize cognitive impairment among men later found to have a dementing disorder. Based on their findings, Ross et al<sup>1</sup>make a case for public health education aimed at increasing awareness of the early signs of dementia and the value of timely evaluation. Early recognition of dementia, as Ross et al<sup>1</sup>note, offers many potential benefits: prompt treatment of reversible causes of dementia and increased time to address safety needs and make financial arrangements and other plans. Ross and colleagues<sup>1</sup>are to be commended for their important work. We strongly endorse their call for a focused educational effort and, in that context, wish to direct attention to the recently published<i>Clinical Practice Guideline Number 19 (CPG19)</i>on recognition and initial assessment of Alzheimer disease and related dementias.
Alcohol, firearms, and suicide among youth. Temporal trends in Allegheny County, Pennsylvania, 1960 to 1983
Authors: D. A. Brent
Journal: JAMA (1987)

The death certificates and coroners' reports for all suicides, undetermined causes of death, and questionable accidents were obtained from the Pennsylvania Department of Vital Statistics for 10- to 19-year-old residents of Allegheny County, Pennsylvania, from 1960 to 1983. During the 24-year study period, 159 cases of definite suicide and 38 cases of likely suicide were noted. The suicide rate increased markedly among youth during the study period, particularly among white males aged 15 to 19 years, and was not due to changes in classification procedures over time. The suicide rate by firearms increased much faster than the suicide rate by other methods (2.5- vs 1.7-fold). The proportion of suicide victims who had detectable blood alcohol levels rose 3.6-fold from 12.9% in 1968 to 1972 to 46.0% in 1978 to 1983. Suicide victims who used firearms were 4.9 times more likely to have been drinking than were those who used other methods of suicide. The availability of firearms and the increased use of alcohol among youth may have made a significant contribution to the increase in the suicide rate among the young. (<i>JAMA</i>1987;257:3369-3372)
Memoir on Turning, as an Alternative for Craniotomy and the Long Forceps, in Deformity of the Brim of the Pelvis, &amp;c. &amp;c
Authors: J. Y. Simpson
Journal: BMJ (1847)

At a meeting of the Obstetric Society, of Edinburgb, beld on the 20th of January, 1847,1 had an opportunity of shewing to the members a large infant, extracted on the preceding erening by the operation of turning, through a pelvis, the brim of which was greatly con- tracted.The following particulars were at the sam-e time stated regarding the history of the case.CASE I.-The mother was very lame, with the lumbar vertebra much distorted, and had been twice pregnant.Her first labour had been extremely protracted, In, consequence of the promontory of the sacrum pro- jecting forwards and downwards, so as to diminish much the conjugate diameter of the brim.After being several days in labour, symptoms requiring interference supervened, and Mr. Figg, her medical attendant, availed himself of the able advice of my friends, Drs. Malcolm and Marr.These gentlemen considered it
Preoperative Neural Network Using Combined Magnetic Resonance Imaging Variables, Prostate Specific Antigen, and Gleason Score to Predict Prostate Cancer Recurrence after Radical Prostatectomy
Authors: Vassilis Poulakis, Ulrich Witzsch, Rachelle de Vries, Volker Emmerlich, Michael Meves, Hans-Michael Altmannsberger, Eduard Becht
Journal: European Urology (2004)