tbuckley/cabot-search huggingface dataset:
Hypertensive crisis
Authors: E. D. Freis
Journal: JAMA (1969)

Hypertensive crisis is a medical emergency requiring early, expert, and intensive treatment. It is a life-threatening disorder characterized by acute or severe elevation of blood pressure and by clinical manifestations secondary to the hypertension and to associated arteriolar spasm or damage. The clinical manifestations may include encephalopathy, neuroretinitis, evidences of rapidly advancing renal impairment, and acute heart failure. A number of diseases can be associated with hypertensive crisis, the most common being the accelerated or malignant phase of essential hypertension. Renal diseases, such as acute and chronic glomerulonephritis, chronic pyelonephritis, collagen vascular disease, and renovascular hypertension also are frequent causes. Sudden elevations of blood pressure which may not be sustained but are severe enough to be lifethreatening can occur in patients with pheochromocytoma. In patients receiving treatment with monoamine oxidase inhibitors, a hypertensive crisis is precipitated by administration of sympathomimetic drugs, such as ephedrine or amphetamines, or by ingestion of
Are the responses to bFGF and VEGF similar in human arteries compared to other species? John D. Altman, Mehrdad Rezaee, Antonio Bayes-Genis, Dieter Lubbe, Birgit Kantor, Paula Carlson, Thomas Quertermous, David R. Holmes, Jr., Robert S. Schwartz. Mayo Clinic, Rochester, MN, Stanford University, Stanford, CA
Journal: Journal of the American College of Cardiology (2001)
A Comparison of Aripiprazole, Methylphenidate, and Placebo for Amphetamine Dependence
Authors: Jari Tiihonen
Journal: American Journal of Psychiatry (2007)

Objective: Problems related to illegal amphetamine use have become a major public health issue in many developed countries. To date, evidence on the effectiveness of psychosocial treatments has remained modest, and no pharmacotherapy has proven effective for amphetamine dependence. Method: Individuals meeting DSM-IV criteria for intravenous amphetamine dependence (N=53) were randomly assigned to receive aripiprazole (15 mg/day), slow-release methylphenidate (54 mg/day), or placebo for 20 weeks. The study was terminated prematurely due to unexpected results of interim analysis. An intention-to-treat analysis was used. The primary outcome measure was the proportion of amphetamine-positive urine samples. Results: Patients allocated to aripiprazole had significantly more amphetamine-positive urine samples than patients in the placebo group (odds ratio=3.77, 95% CI=1.55–9.18), whereas patients who received methylphenidate had significantly fewer amphetamine-positive urine samples than patients who had received placebo (odds ratio=0.46, 95% CI=0.26–0.81). Conclusions: Methylphenidate is an effective treatment for reducing intravenous drug use in patients with severe amphetamine dependence.
Pernicious anemia and the development of carcinoid tumors of the stomach
Authors: A. I. Harris
Journal: JAMA (1978)

CARCINOID tumors of the stomach are rare. To our knowledge, there are 93 cases reported in the literature before 1970.<sup>1</sup>Numerous gastric carcinoids are more unusual, with nine reports before 1971.<sup>2,3</sup>There have been four cases of pernicious anemia associated with gastric carcinoid mentioned in the English literature,<sup>1,2,4,5</sup>one of which concerned a patient with seven tumors in his stomach.<sup>2</sup>We treated a patient with pernicious anemia and gastric carcinoid. This report also represents the second case of numerous (four) tumors in a patient with pernicious anemia. It also demonstrates the value of endoscopic biopsy in the diagnosis of these lesions before surgery.<sup>1,3</sup> <h3>Report of a Case</h3> A 33-year-old man was admitted to the Mount Sinai Hospital in May 1976 because of a polypoid defect detected in the stomach during an upper gastrointestinal (GI) tract series. The patient had pernicious anemia since March 1974 but
Editorial Board
Authors: James Kemp, Gail Shapiro, San Diego, William Busse, Stephen Wasserman, Gary Rachelefsky, Robert Bush, Lanny Rosenwasser, Thomas Fischer, Hugh Sampson, New York, Clifton Furukawa, Seattle Wa, Michael Schatz, Gailen Marshall, William Shearer, Robert Nathan, Colorado Springs
Journal: Journal of Allergy and Clinical Immunology (2000)
Antiarrhythmic Drug Therapy vs Catheter Ablation for Paroxysmal Atrial Fibrillation
Authors: Alfred A. Rimm
Journal: JAMA (2010)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hazards of radiation exposure for pregnant women
Authors: H. M. Swartz
Journal: JAMA (1978)

CONCERN over the effects of radiation, especially in pregnant women, has increased along with the public concern over other potentially toxic factors in the environment. The emotional content of this concern is heightened in too many cases by physicians' ignorance of the subject. Here, as elsewhere in medicine, the key to reasonable public action is education on the real issues, and an essential starting point is the education of primary physicians. The goal of this article is to enable physicians to give confident, appropriate, convincing advice regarding radiation exposure of pregnant women. <h3>Levels of Radiation Pregnant Women May Receive</h3> Medical effects of radiation are dose dependent. The Table lists radiation doses for a number of common procedures. The dose that your patient receives may differ somewhat, depending on the conditions of the exposure, but in the absence of specific information the values in the Table provide an approximation. As will
Genetic Modulation of the Cellular Antioxidant Defense Capacity
Authors: Paul Amstad, Peter Cerutti
Journal: Environmental Health Perspectives (1990)

Oxidants are ubiquitous in our aerobic environment. While they are always toxic, they can also exert pathophysiological effects at low concentrations and play an etiological role in human disease. For example, oxidants can stimulate cell growth and act as tumor promoters. The cellular antioxidant defense system attenuates the effect of oxidants and consists of low molecular weight components and several enzymes. Most important are catalase (CAT), superoxide dismutases (SOD), and glutathione peroxidase. We are attempting to elucidate the role of CAT and Cu,Zn-SOD in oxidant tumor promotion of mouse epidermal cells JB6. We have found that the promotable clone 41 possesses 2- to 3-fold higher levels of activity, protein, and stationary mRNA of CAT and Cu,Zn-SOD than does the nonpromotable clone 30. We propose that the growth-stimulatory effect of oxidants is more pronounced in promotable clone 41 because it is better protected from oxidant toxicity. In order to corroborate this model, we have constructed JB6 cells with higher levels of Cu,Zn-SOD and CAT by transfection with expression vectors containing cDNA for these genes. On the other hand, cells with decreased amounts of Cu,Zn-SOD have been obtained by their stable transfection with a vector containing SOD-cDNA in the antisense orientation. These cell clones with modified antioxidant enzyme complements are being characterized. In particular, their promotability by oxidants and their sensitivity to killing and oxidative macromolecular damage are being measured. Certain tumor promoters that lack oxidizing properties may generate a cellular prooxidant state by a variety of mechanisms.(ABSTRACT TRUNCATED AT 250 WORDS)
Black/White Comparisons of Premature Mortality for Public Health Program Planning—District of Columbia
Journal: JAMA (1989)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Immunization Treatment of Hay Fever.
Authors: E. Fletcher Ingals
Journal: JAMA (1902)

Chicago, Nov. 5, 1902. <h3>To the Editor:</h3> —I have carefully read and re-read Dr. Curtis' letter referring to my article in the issue of June 28, and I am unable to discover anything whatever to substantiate his statement that "In this paper there were so many statements that are at variance with facts and so many misrepresentations with regard to myself that I am obliged to ask you to publish this letter." The Doctor seems to take special umbrage at my statement: "Fraser's liquor ambrosia is a proprietary preparation, the constituents of which are not known to the profession." He says further: "The entire tenor of this article makes it appear that he is doing a noble work with simple fluid extracts and an insinuation is made that I am using in my experiments a secret compound made by Fraser &amp; Co., called liquor ambrosia." In answer to the above,
Re: Christian Bolenz, Stephen J. Freedland, Brent K. Hollenbeck, et al. Costs of Radical Prostatectomy for Prostate Cancer: A Systematic Review. Eur Urol. In press. http://dx.doi.org/10.1016/j.eururo.2012.08.059
Authors: Jens Rassweiler
Journal: European Urology (2012)
WEAR THEM IN GOOD HEALTH
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
天疱疮复发的临床和免疫学特征
Authors: I. Ujiie, H. Ujiie, H. Iwata, H. Shimizu
Journal: British Journal of Dermatology (2019)

天疱疮是一种潜在致命的大疱性皮肤病。这是一种自身免疫性疾病,意味着通常情况下抗击疾病的人体免疫系统实际攻击了健康细胞。天疱疮的主要治疗是使用称作皮质类固醇或免疫抑制剂的药物。治疗目的在于实现缓解,即,在进行极少治疗或无治疗(药物)的情况下没有新的病变出现(受累皮肤区域)。但许多患者出现多次复发,即经过一段时间改善后,疾病再次恶化,而且患者通常很难再实现缓解。这项日本的研究旨在了解天疱疮复发的风险因素和临床特征(体征)的更多信息。作者回顾性分析了42名天疱疮患者的病历。61.9%病例出现复发,通常发生在一种称作口服泼尼松龙的药物剂量逐渐减至约 0.1 mg/kg 时。在一种称作皮肤粘膜寻常型天疱疮 (mcPV) 的天疱疮中,泼尼松龙的初始剂量在复发病例中较未复发病例更低。在复发时,mcPV 转变为不同亚型(表型),即粘膜显性PV(mPV,其主要累及口腔而非皮肤)(40%)、落叶型天疱疮(PF,累及皮肤)(20%) 或其他类型 (20%)。相对而言,复发性 mPV 及 PF具有和初始表型相同的临床表型。分析免疫系统生成哪些抗体以帮助抗击疾病时发现,患者一开始拥有抗‐Dsg1 和抗‐Dsg3 抗体,出现复发后单纯拥有抗‐Dsg3 抗体 (40%),同时拥有抗‐Dsg1和Dsg3抗体(30%)或单纯拥有抗‐Dsg1抗体(20%)。总之,当 mcPV患者复发后,他们的疾病表型及其生成的抗体可能发生改变。按至少1mg/kg/天服用泼尼松龙,尤其用于mcPV病例,然后将剂量谨慎减少至约0.1 mg/kg可能会使结局更佳。
Robot-assisted cystectomy with intracorporeal urinary diversion after pelvic irradiation for prostate cancer: Technique and results from a single high-volume center
Authors: P. Piazza, G. Rosiello, V. Tames, S. Puliatti, M. Amato, R. Farinha, C. Bravi, R. Schiavina, E. Brunocilla, C. Berquin, D. Dries, C. Sinatti, H. Van Puyvelde, R. De Groote, P. Schatteman, G.. De Naeyer, F. D’hondt, A. Mottrie
Journal: European Urology (2021)
Modern Diagnosis and Treatment of Syphilis, Chancroid and Gonorrhoea.
Journal: JAMA (1926)

This is a concise, yet complete, treatise on the modern methods of diagnosing and treating venereal diseases. Having written for the practitioner, the author does not indulge in extensive literary quotations and confines himself in his theoretical explanations to the essentials. While the microscopic and serum tests are thoroughly discussed as to principles and the conclusions to be derived from them, the clinical evidence is by no means neglected. The various drugs to be employed and their administration is extolled, with presentation of sound, constructive criticism. The major part of the book is devoted to the discussion of syphilis. The chapters on gonorrhea do not come up quite to the standard of those dealing with syphilis, and American authors may take exception to the emphatic recommendation of the forced Janet irrigation and the strong belief in the efficacy of the vaccine therapy. The work is a valuable guide for the
New normal values for thyroid uptake of radioactive iodine
Authors: G. G. Ghahremani
Journal: JAMA (1971)

A 24-hour thyroid uptake test of sodium iodide I131 performed on 66 euthyroid subjects in Chicago has been analyzed. The new normal range, based on mean ± 2 standard deviations is 7% to 33%, which could explain the discrepancies between patient's clinical status and the results of the uptake test if data previously considered normal (15% to 45%), were applied.
Old Together
Authors: Donna Pucciani
Journal: JAMA (2012)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
EXAGGERATIONS REGARDING TRICHINOSIS.
Journal: JAMA (1892)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A multicenter sequential phase IV study of oxaliplatin (Oxa) and capecitabine (Cap) followed by irinotecan (Iri) and capecitabine in first line advanced colorectal cancer (ACC). Preliminary results
Authors: L. De La Cruz, A. Albero, M. M. Barros, A. Moreno, J. A. Virizuela, M. J. Sánchez, R. De Toro, M. Portillo, J. C. Toral, A. Duque
Journal: Journal of Clinical Oncology (2004)

3652
States continue to look at work hours and supervision
Journal: JAMA (1989)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Sakurai Injectable Silicone Formula
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Die Chirurgischen Untersuchungs-Methoden.
Journal: JAMA (1913)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE RETURNS ARE IN.
Journal: JAMA (1894)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal