tbuckley/cabot-search huggingface dataset:
A cautionary tale
Authors: S. Flann, R. Moss, T. Thompson, M. Clement, K. Powell, S. Munn
Journal: British Journal of Dermatology (2008)

Journal Article A cautionary tale Get access S. Flann, S. Flann Department of Dermatology, Orpington Hospital, Orpington, Kent BR6 9JU, U.K. E‐mail: sandy.flann@hotmail.com Search for other works by this author on: Oxford Academic Google Scholar R. Moss, R. Moss Department of Dermatology, Orpington Hospital, Orpington, Kent BR6 9JU, U.K. E‐mail: sandy.flann@hotmail.com Search for other works by this author on: Oxford Academic Google Scholar T. Thompson, T. Thompson Department of Dermatology, Orpington Hospital, Orpington, Kent BR6 9JU, U.K. E‐mail: sandy.flann@hotmail.com Search for other works by this author on: Oxford Academic Google Scholar M. Clement, M. Clement Department of Dermatology, Orpington Hospital, Orpington, Kent BR6 9JU, U.K. E‐mail: sandy.flann@hotmail.com Search for other works by this author on: Oxford Academic Google Scholar K. Powell, K. Powell Department of Dermatology, Orpington Hospital, Orpington, Kent BR6 9JU, U.K. E‐mail: sandy.flann@hotmail.com Search for other works by this author on: Oxford Academic Google Scholar S. Munn S. Munn Department of Dermatology, Orpington Hospital, Orpington, Kent BR6 9JU, U.K. E‐mail: sandy.flann@hotmail.com Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 159, Issue 3, 1 September 2008, Pages 746–748, https://doi.org/10.1111/j.1365-2133.2008.08714.x Published: 01 September 2008
Cancer Immunotherapy
Authors: ROBERT T. EAGAN
Journal: Annals of Internal Medicine (1973)

Letters, Comments, and Corrections1 January 1973Cancer ImmunotherapyROBERT T. EAGAN, M.D.ROBERT T. EAGAN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-78-1-153_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: After all the articles in the lay press and news media about "cures" of cancer with bacillus Calmette-Guérin (BCG) and other forms of immunotherapy and after receiving more than one phone call at the Cancer Information Center, Northern New England Cancer Project, about "curing" leukemia with active immunization rather than with chemotherapy, it is worth clarifying a paragraph in the recently published UCLA Conference "Recent Advances in Oncology," moderated by Dr. Donald L. Morton, (Ann Intern Med77:431-454, 1972). The paragraph is on page 435, and the four sentences that need clarifying are as follows: "Seven acute...Reference1. CLARKSONFRIED BJ: Changing concepts of treatment in acute leukemia. Med Clin North Am 55:561-600, 1971 CrossrefMedlineGoogle Scholar1. : Treatment of acute lymphoblastic leukemia. Comparison of immunotherapy (B.C.G.), intermittent methotrexate, and no therapy after a five-month intensive cytoxic regimen (Concord Trial). Br Med J 4:189-194, 1971 MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Dartmouth Medical School Hanover, N.H. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByProlonged Survival of Patients Receiving Active Immunotherapy With Canvaxin Therapeutic Polyvalent Vaccine After Complete Resection of Melanoma Metastatic to Regional Lymph NodesIsatoic Anhydrides and Their Uses in Heterocyclic Synthesis 1 January 1973Volume 78, Issue 1Page: 153-154KeywordsBacille calmette guerinBacillusCancer chemotherapyCancer immunotherapyChemotherapyVaccination and immunization Issue Published: 1 January 1973 PDF DownloadLoading ...
Correction to Kwako et al.
Journal: American Journal of Psychiatry (2019)

Although we recognize that discontinuation symptoms can be challenging, the alternative of not prescribing antidepressant medications is also not a viable option for those who are likely to benefit.The need for carefully well-designed clinical trials specifically addressing discontinuation cannot be overemphasized.For example, in a recent review article, Horowitz and Taylor argue that taper should be even slower and that the minimum medication dosage preceding discontinuation should be much lower than the therapeutic minimum in order to prevent the occurrence of discontinuation symptoms (6).Such strategies need to be tested prospectively.To get an accurate assessment of prevalence and duration of discontinuation symptoms in clinical practice, large naturalistic studies are needed where patients with depression are enrolled and followed prospectively as they get care during routine clinical care (e.g., ClinicalTrials.gov identifier: NCT02919280).Furthermore, measurementbased practice of systematically assessing discontinuation symptoms and documenting these in clinical practice may facilitate survey of these symptoms through electronic health records (e.g., ClinicalTrials.gov
Associations between Soil Lead and Childhood Blood Lead in Urban New Orleans and Rural Lafourche Parish of Louisiana
Authors: Howard W. Mielke, Dianne Dugas, Paul W. Mielke, Kabrina S. Smith, Stephanie L. Smith, Chris R. Gonzales
Journal: Environmental Health Perspectives (1997)

This study evaluates associations between soil lead concentrations (SPb), age of housing, and blood lead levels (BPb) of children in metropolitan New Orleans and Lafourche Parish, Louisiana. The database includes over 2,600 SPb and 6,000 BPb samples paired by their median values and pre-1940 housing percentages for 172 census tracts. Associations were evaluated with Fisher's exact test and Spearman's rho test and modeled with the least sum of absolute deviations regression. Census tracts with low SPb are associated with new housing, but census tracts with high SPb are evenly split between old and new housing [Fisher's exact test, p = 8.60 X 10(-13) for the percentage of housing built before 1940 (percent pre-1940 housing) versus SPb]. The p-value for SPb versus BPb is 12 orders of magnitude stronger than the p-value for percent pre-1940 housing versus BPb. Census tracts with low BPb are associated with new housing, but census tracts with high BPb are split evenly between old and new housing (Fisher's exact test, p = 1. 67 X 10(-12) for percent pre-1940 housing versus BPb). Census tracts with high SPb are associated with high BPb and census tracts with low SPb are associated with low BPb (Fisher's exact test, p = 3.18 X 10(-24) for BPb versus SPb). The Spearman's rho test of the association of SPb and BPb in Orleans and Lafourche Parishes yielded a p-value of 6.12 X 10(-24). The least sum of absolute deviations regression model of the data is BPb = 1. 845 + 0.7215 (SPb)0.4. A comparison of the modeled BPb versus observed BPb has an r(2) of 0.552 and a p-value of 2.83 X 10(-23) that this relation was due to chance. If blood lead in children is more closely associated to soil lead than to the age of housing, then primary lead prevention should also include soil lead.
Negative Results
Journal: JAMA (1962)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Diesel Exhaust Particles Activate the Matrix-Metalloproteinase-1 Gene in Human Bronchial Epithelia in a ß-Arrestin-Dependent Manner via Activation of RAS
Authors: Jinju Li, Andrew J. Ghio, Seung-Hyun Cho, Constance E. Brinckerhoff, Sidney A. Simon, Wolfgang Liedtke
Journal: Environmental Health Perspectives (2008)
Thrombocytopenia in HIV‐infected and uninfected hemophiliacs
Authors: W.C. Ehmann, C.S. Rabkin, M.E. Eyster, J.J. Goedert
Journal: American Journal of Hematology (1997)

To determine the incidence and prognostic significance of thrombocytopenia among hemophiliacs, we analyzed clinical and hematologic data from the Multicenter Hemophilia Cohort study. Nineteen percent of HIV-infected subjects had thrombocytopenia (platelet count of <100,000/mm3) noted at least once, compared to 3% of HIV-uninfected subjects. For HIV-infected subjects, the prevalence of thrombocytopenia rose in the first 5 years after seroconversion and was twice as common in subjects age >35 years compared to younger subjects. The risk increased after an AIDS-defining illness, particularly among older subjects, nearly one-half of whom had thrombocytopenia within 1 year after AIDS. When adjusted for age and CD4-positive lymphocyte counts, thrombocytopenia was associated with an increased risk of death [relative risk (RR) 1.7, 95%Cl = 1.2–2.3] but with little change in the risk of progression to AIDS (RR = 1.2, 95%Cl = 0.8–1.7). Treatment with zidovudine was associated with a decreased risk of thrombocytopenia (RR = 0.5, 95%Cl = 0.3–0.7). Although 59 HIV-infected subjects died of hemorrhage, only 11 (19%) of the 59 had a reported platelet count of <50,000/mm3, and only 2 (3%) of the deaths were temporally associated with thrombocytopenia. Thus, the risk of death was increased for thrombocytopenia HIV-infected hemophiliacs but this was not explained by an increased risk of developing AIDS and was rarely associated with death from bleeding. Am. J. Hematol. 54:296–300, 1997. © 1997 Wiley-Liss, Inc.
A Compend of Diseases of the Skin
Journal: JAMA (1934)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
CONFERENCE ON SCHOOL HYGIENE
Journal: BMJ (1905)

first duty and pleasure to-night is to welcome the members of this ivt Conference to the UnivL-rsIty of London, and to thank you for the llonour you have done me in electing me as president of your gathering.I cannot claim to be an expert in your subject, and though, as a man of science, I sympathise heartily with your aims and objects, and know something of the principles on which they are based, yet I take it that my presence here is a proof of the importance which ,YOU attach to the place of hygiene in any well-considered scheme of education.N eyer, perhaps, wras education more in tlle thoughts of the people of Englalll than it is now.The great decentrahsation, by which the control of the upbringing of our youth was handed over to local authorities, has encouraged many willing and compelled many unwilling recruits to busy themselves with educational matters.The countr3-has not yet settled down to a systcl, or systems, which all approve, and we are feeling our way, in the tentative Englisl fashiun, through a mist of speeches, letters, reports, and conferences to ends which, as a nation, we clu not clearly discern.Progress haa lln(luestionably been made in the last quarter of a century, but it is curious to note how little we have advanced towards agreement on fundamentals, and how unaltered is the attitude of those who hold conflicting opinions as to the older and newer forms of educa- tion.Matthew Arnold's famous jell cl'es~~~~t, &dquo; Friendship's Garland,&dquo; was published thirty-four years ago, and he summed up the views uf tlie
Report on Family with Six Tja-Negative Siblings
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Another artificial heart receives FDA approval for clinical trials
Journal: JAMA (1985)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Prognostic Value of Interleukin-8 in AIDS-associated <i>Pneumocystis carinii</i> Pneumonia
Authors: Thomas L. Benfield, Jørgen Vestbo, Jette Junge, Thyge L. Nielsen, Anne-Mette Bæk Jensen, Jens D. Lundgren
Journal: American Journal of Respiratory and Critical Care Medicine (1995)

Interleukin-8 (IL-8) is a potent neutrophil chemoattractant and activator. Pneumocystis carinii pneumonia is associated with an accumulation of neutrophils in bronchoalveolar lavage (BAL) fluid. Thus, we hypothesized that IL-8 is involved in the pathogenesis of P. carinii pneumonia. BAL fluid and serum were prospectively collected in 76 consecutive HIV-infected patients with a primary episode of P. carinii pneumonia, as well as in 10 healthy control subjects. Patients were found to have elevated levels of IL-8 in BAL fluid compared with control subjects (p < 0.01). Nine patients died during the course of P. carinii pneumonia. Comparing survivors with nonsurvivors, the median IL-8 level in BAL fluid was 127 (0 to 3,900) versus 584 (127 to 6,100) pg/ml (p < 0.05). Furthermore, patients with levels of IL-8 in BAL fluid greater than 90 pg/ml (i.e., greater than control subjects) had significantly worse vital prognosis (log rank test, p < 0.05). Thirteen percent required mechanical ventilation (MV). Patients requiring MV had a median IL-8 level of 396 (25 to 6,100) versus 129 (0 to 3,900) pg/ml for patients not requiring MV (p < 0.05). In conclusion: i) IL-8 in BAL fluid correlates to the clinical severity of the pneumonia, and ii) is a predictor of mortality and severe respiratory compromise.
On the Liability of Soldiers to Contract Diseases of the Circulatory System
Authors: D. Cullen
Journal: BMJ (1883)

LJun 2a, 188& continuous layer.In the fornationof the central nervous system,both strata of the epiblast have a sbare, though the principal portion is derived from the nervous layer.After the central tube bas become separated from the external skin, the two layers forming it fuse together, but there is little doubt that, at a later period, the epidermic layer separates itself again as the central epithelium of the nervous
Large sella
Authors: A. A. Chambers
Journal: JAMA (1979)

<h3>Common</h3> Pituitary tumor (eg, chromophobe adenoma) Craniopharyngioma Aneurysm of the internal carotid artery Empty sella Increased intracranial pressure Juxtasellar tumor (eg, chiasmatic glioma) Osteoporosis <h3>Rare</h3> Basal encephalocele Chondroma Chordoma Cretinism Hurler's syndrome Hypogonadism Metastatic neoplasm Mucocele of sphenoid sinus Sphenoid sinus neoplasm Neurofibromatosis with dysplastic changes Osteomyelitis Postoperative change <h3>Comment</h3> The details of sellar anatomy are essential for diagnosis and treatment of pituitary lesions.<sup>1</sup>Roentgenograms of the sella must be carefully taken, since rotated views lead to misinterpretation. On a lateral film, the maximum normal measurements of the sella are 17 mm from tuberculum to dorsum and 14 mm in depth. The floor of the sella is often difficult to see, even on the best quality posteroanterior view. It should measure 10 to 15 mm in transverse diameter. Volumetric measurements
Binding of the Journal.
Journal: JAMA (1884)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hearing Loss
Authors: Carrie L. Nieman, Esther S. Oh
Journal: Annals of Internal Medicine (2020)

Hearing loss is highly prevalent and may significantly affect how we age. Although the population is aging, relatively few adults receive treatment for hearing loss. Internists are a critical partner to audiologists and otolaryngologists in caring for the adult population with hearing loss. This review provides a primer on diagnosing and managing hearing loss.
Frequent asymptomatic pulmonary embolism in patients with deep venous thrombosis
Authors: K. M. Moser
Journal: JAMA (1994)

<h3>Objective.</h3> —To determine the frequency of pulmonary embolism in patients admitted for treatment of deep venous thrombosis. <h3>Design.</h3> —An open, multicenter, dose-ranging study to assess the safety and pharmacokinetic characteristics of tissue-type plasminogen activator in deep venous thrombosis and pulmonary embolism. Perfusion and ventilation lung scans, chest roentgenograms, and venograms (in deep venous thrombosis) or pulmonary angiograms (in pulmonary embolism) were obtained before and 24 hours after inception of therapy. Heparin therapy was then administered. <h3>Settings.</h3> —Five tertiary-care hospitals. <h3>Patients.</h3> —All patients with suspected deep venous thrombosis or pulmonary embolism seen from August 1987 through November 1988 entered the study if they met inclusion criteria and if the diagnosis was confirmed by venogram (deep venous thrombosis) or pulmonary angiogram (pulmonary embolism). <h3>Interventions.</h3> —All patients received tissue-type plasminogen activator followed by intravenous heparin therapy. <h3>Main Outcome Measures.</h3> —The primary measure was the frequency of pulmonary embolism in patients with deep venous thrombosis who had no symptoms of pulmonary embolism. This was not the original purpose of the study but emerged as an important finding as the data were analyzed. <h3>Results.</h3> —Nearly 40% of patients with deep venous thrombosis who had no symptoms of pulmonary embolism had evidence of pulmonary embolism based on ventilation-perfusion scan and chest roentgenogram findings. <h3>Conclusions.</h3> —Because all of those considered to have embolism had so-called high-probability scan results, the frequency of embolism reported likely represents the minimum incidence of pulmonary embolism in patients with deep venous thrombosis who have no embolic symptoms. These data emphasize that venous thromboembolism is one disorder. (<i>JAMA</i>. 1994;271:223-225)
<i>Psychological Mcdicine</i>. A Manual of Mental Diseases for Practitioners and Students. By Maurice Craig, M. A., M. D. (Cantab.), F. R. C. P. (Lond.), Physician for and Lecturer in Psychological Medicine, Guy's Hospital. (<i>Philadelphia: P. Blakiston's Son &amp;amp; Co., 1912</i>.)
Journal: American Journal of Psychiatry (1913)
Abstracts&lt;xref ref-type="fn" rid="fn1"&gt;&lt;sup&gt;1&lt;/sup&gt;&lt;/xref&gt;
Journal: JNCI Journal of the National Cancer Institute (1948)

Journal Article Abstracts Get access JNCI: Journal of the National Cancer Institute, Volume 8, Issue 4, February 1948, Pages 199–200, https://doi.org/10.1093/jnci/8.4.199 Published: 01 February 1948