tbuckley/cabot-search huggingface dataset:
Post Mortem Examination in Prisons
Journal: BMJ (1882)

TYPHOID AT VENTNOR?SIR,-A charge of the most mischievous nature was brought on the Ist instant, in two of the London evening papers, against the sanitary state of Ventnor, by a Mr. W. J. Ebbett of London: that several (unspecified) cases of typhoid fever had occurred at Ventnor this autumn.The allegations have naturally caused a sensation in the town, and terrorised intending visitors, of which I have two examples among my own distant friends.The medical practitioners have promptly confuted the general charge as to the prevalence of typhoid; but no one, so far, has analysed Mr. Ebbett's injurious communication, and replied seriatimz to his statement of fact.Let me do this as briefly as possible in the ear of the faculty.i.Mr. Ebbett states, that the outflow of the main sewage is " close to the shore"; 2, that " the sewage is seen at the outflow, at low tides"; 3, that said " outflow is near the pier" (a public promenade); 4, that it is " in proximity to the bathing-place".If these four imputed facts were truths, no more serious indictment could be framed against the authorities of the town; but the facts are each of them untrue, and, in their combination, give a distorted colour to the whole case.I.The outflow is nzot " close to the shore", but is carried far out into the flow of every tide-wave, at high or low water, at the instance of a sanitary engineer. 2. The sewage canzzot be seen at the lowest possible tide. 3. The outflow is distant from the pier, on the east side of it. 4. The bathing-place is on the cst side, at least a quarter of a mile distant.So much for the discrepancy between facts and truths.One word of comment.I suppose there is not a town in the United Kingdom, of 5,000 inhabitants and upwards, where there are not one or more isolated cases of typhoid fever every year, be the situation littoral or inland; and so an isolated case may be at Ventnor.But this is no reason why the place should be blazoned and vilified as it lhas been.One of the local journals urges the authorities to institute legal pro- ceedings against the libeller.If I might advise, I say No. Leave him to the slings and arrows of his own conscience; but let him under- stand that no remorse of conscience can atone for the gratuitous inijury he has inflicted on this health-giving winter resort.-Yourstruly, CORNELIUS NICHiOLSON, J.P I. D.L. Ashleigh, Ventnor, November 5th, I882.
Azathioprine-Induced Meningitis in Systemic Lupus Erythematosus
Authors: Michael Lockshin
Journal: JAMA (1978)

<h3>To the Editor.—</h3> The article by Widener and Littman (239:1062, 1978) describes a case of recurrent aseptic meningitis induced by ibuprofen in a patient with systemic lupus erythematosus (LE). Although aseptic meningitis has been reported repeatedly in LE, the authors state that "to our knowledge this is the first reported case of aseptic meningitis as a manifestation of an adverse reaction to an ingested drug." In a large review of CNS disease and systemic LE,<sup>1</sup>we described two patients who had episodes of recurrent aseptic meningitis induced by azathioprine. Both of these patients have had at least one episode of aseptic meningitis apparently related to the underlying disease. Both patients recovered completely, with no known neurologic sequelae. We believe that our cases, in addition to that of Widener and Littman, underscore the fact that, at least in patients with systemic LE, the possibility of an adverse drug reaction must
Abortion Surveillance: Preliminary Analysis— United States, 1986 and 1987
Journal: JAMA (1989)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Topical use of hydroquinone for depigmentation
Authors: M. C. Spencer
Journal: JAMA (1965)

Autoxidation of hydroquinone in ointments used for depigmentation may reduce its effectiveness. In this study low concentrations (2%, 3%, 5%) of stabilized hydroquinone were used for depigmenting "old age spots" on the hands of 94 white men. Also treated were 43 Negro men with normal skin. Higher concentrations of hydroquinone may produce sensitization. Lower concentrations are less likely to. Although the depigmentation produced by topical hydroquinone is limited, it is, in our experience, the best available depigmenting agent.
Effectiveness of Drug Therapy in Hypertension: Present Status
Authors: EDWARD D. FREIS
Journal: Circulation Research (1971)

Progress in the development of effective antihypertensive agents is briefly reviewed. Evidence that drug treatment reduces the incidence of major complications is presented. The recently completed controlled trial carried out in Veterans Administration hospitals indicates that in men with diastolic blood pressure levels of 90 through 114 mm Hg the risk of developing a morbid event over a five-year period was reduced from 55% to 18% by treatment. The degree of benefit was proportional to the risk, which in turn was related directly to the level of blood pressure.
Air Pollution and Bronchitic Symptoms in Southern California Children with Asthma
Authors: Rob McConnell, Kiros Berhane, Frank Gilliland, Stephanie J. London, Hita Vora, Edward Avol, W. James Gauderman, Helene G. Margolis, Fred Lurmann, Duncan C. Thomas, John M. Peters
Journal: Environmental Health Perspectives (1999)

The association of air pollution with the prevalence of chronic lower respiratory tract symptoms among children with a history of asthma or related symptoms was examined in a cross-sectional study. Parents of a total of 3,676 fourth, seventh, and tenth graders from classrooms in 12 communities in Southern California completed questionnaires that characterized the children's histories of respiratory illness and associated risk factors. The prevalences of bronchitis, chronic phlegm, and chronic cough were investigated among children with a history of asthma, wheeze without diagnosed asthma, and neither wheeze nor asthma. Average ambient annual exposure to ozone, particulate matter (PM(10) and PM(2.5); [less than/equal to] 10 microm and < 2.5 microm in aerodynamic diameter, respectively), acid vapor, and nitrogen dioxide (NO(2)) was estimated from monitoring stations in each community. Positive associations between air pollution and bronchitis and phlegm were observed only among children with asthma. As PM(10) increased across communities, there was a corresponding increase in the risk per interquartile range of bronchitis [odds ratio (OR) 1.4/19 microg/m(3); 95% confidence interval (CI), 1.1-1.8). Increased prevalence of phlegm was significantly associated with increasing exposure to all ambient pollutants except ozone. The strongest association was for NO(2), based on relative risk per interquartile range in the 12 communities (OR 2.7/24 ppb; CI, 1.4-5.3). The results suggest that children with a prior diagnosis of asthma are more likely to develop persistent lower respiratory tract symptoms when exposed to air pollution in Southern California.
The Education and Training of Girls: A Correction
Journal: BMJ (1895)

A MEMBsER.-India-rubber when new may give a taste to water, but this tendency disappears after use for a week or two.A taste in any fllter may also arise from the sides of the vessel and the surface of the filtering medium being left uncleaned and exposed for air; and this taste is often mistaken for that of india-rubber.The remedy is to keep the filter as constantly full as possible, and to clean occasionally, prefer- ably scalding out with boiling water.If this has been neglected, a little acid (for example, cltric acid) dissolved in the water is useful.Of course filter-ed water should not be kept in the reservoir till it becomes offensive, but should be emptied out, preferably every day.GERMAN AND FRENCH MEDICO-SCIENTIFIC DICTIONARIES.A MEMBER will probably flnd the National Mledical Dictionarry, edited by Dr. J. S. Billings, the book most suited to his purpose.It is published In two volumes, and centains English, French, German, Italian, and Latin scientific and medical terms.The price is £2 10s.nett.
A Correction
Journal: BMJ (1892)

THE CHOLERA.[Tin Bar 903 who obtained their milk supply at this shop there were 16 cases of typhoid fever reported between August 24th and September 21st.It is ,nteresting to trace the rise and subsidence of this special outbreak.F'rom August 20th to the 31st, 19 cases were reported; from September 1st to the 10th, 18 cases; between September 10th and the 27th there were 6 -cases, and none since.It is another illustration of the value of compul- sory notification of infectious diseases, and of the sensitiveness of milk to infection.The Committee instructed the sanitary inspector to intimate to all -dairymen and milk retailers throughout the city that the Commissioners desire that hereafter they shall give notice at the sanitary office of every ease of illness occurring in the dwelling houses of other piemises, what- ever it might be, immediately on such illness occurrine; further, the Sanitary Inspector was instructed (l) to see that all c airies and milk- shops are kept and maintained in proper order and repair, and in a state of perfect cleanliness; (2) to report all cases where dairymen or milk re- tailers, or any of their families, sleep on the premises of the dairy or milkshop; and (3) to bring up a report specifying all wells at or near dairies or milkshops, and whether water is supplied to any dairy or milk- shop from any such wells.
Hemodynamic study during transdermal application of nitroglycerin tape in patients with cirrhosis
Authors: T Iwao
Journal: Hepatology (1991)

We studied 14 patients with portal hypertension and cirrhosis using portal and hepatic vein catheterizations to determine the effects of transdermal application of nitroglycerin tape (containing 10 mg of nitroglycerin and capable of releasing 6 to 7 mg of nitroglycerin in 12 hr) on splanchnic hemodynamics. Patients randomly received nitroglycerin (n = 7) or a placebo (n = 7). No significant changes were observed after the administration of the placebo. In contrast, transdermal nitroglycerin caused a significant reduction in portal pressure, as evaluated by measurements of the portal venous pressure gradient (−22%, p < 0.01). The reduction of portal pressure was due to a decrease in the portal venous pressure, with no changes in the free hepatic venous pressure. Despite the fall in portal pressure, the hepatic blood flow was maintained. These findings suggest that transdermal nitroglycerin could be potentially useful in the treatment of portal hypertension associated with cirrhosis. (HEPATOLOGY 1991;13:124–128).
Clinical effectiveness of a newly developed and fully automated high-sensitive hepatitis B core-related antigen assay for monitoring nucleos(t)ide analogues therapy in hepatitis B envelope antigen-negative patients
Authors: Takako Inoue, Kentaro Matsuura, Etsuko Iio, Kei Fujiwara, Shintaro Ogawa, Chiharu Ohue, Shintaro Yagi, Katsumi Aoyagi, Yasuhito Tanaka
Journal: Journal of Hepatology (2020)
Thrombotic endocarditis
Authors: K. M Evans
Journal: Journal of the Royal Society of Medicine (2005)

On sectioning, the spleen contained a large fibrous-walled pseudocyst filled with altered blood and clots.One pole was adherent to part of the left hemidiaphragm.Postoperatively the patient succumbed to acute respiratory distress syndrome. COMMENTThe most likely differential diagnoses for a man of this age with massive splenomegaly associated with anaemia, unilateral pleural effusion and weight loss are a myeloproliferative or lymphoproliferative disorder, portal hypertension in the context of cirrhotic liver disease, malignancy and infiltrative conditions such as amyloidosis.Chronic infections such as brucellosis could present in the same way but were unlikely in the present case because of the lack of travel outside the UK.The probable train of events was haemorrhage into the pseudocyst and fistulation into the left hemithorax.The absence of tachycardia after syncope may be explained by his treatment with a beta-blocker.Splenic cysts can be classified as primary or secondary (pseudocyst).Pseudocysts constitute 56% of all nonparasitic splenic cysts and are mostly of traumatic origin. 1 Indeed, the spleen is the intra-abdominal organ most commonly injured by blunt abdominal trauma and up to a quarter of patients with blunt splenic trauma sustain pleuropulmonary complications (lung contusion, pleural effusion). 2Our patient was unable to recall any previous trauma and witnesses reported none during his presenting syncopal episode.Splenic pseudocysts are commonly silent but can be complicated by abscess formation and rupture, leading to acute abdomen and haemoperitoneum. 2 Rupture into the chest has been recorded in blunt splenic trauma, hydatidosis, angiosarcoma and chronic myeloid leukaemia. [3]4][5][6] Spontaneous rupture of a pseudocyst, with a splenothoracic fistula and haemothorax, is clearly very unusual-especially in the absence of a haemoperitoneum.
Penicillin Treatment of Gonorrheal Urethritis: Effects of Penicillin Susceptibility of Causative Organism and Concomitant Presence of Penicillinase-Producing Bacteria on Results
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Taschenbuch der Magen- und Darmkrankheiten.
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE UNITED DOCTORS
Journal: JAMA (1913)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
PROfusion™: Genetically Tagged Proteins for Functional Proteomics and Beyond
Authors: Brent L. Kreider
Journal: Medicinal Research Reviews (2000)

As a new enabling technology in functional genomics, Phylos, Inc. has pioneered PROfusion™ technology, whereby proteins are covalently tagged with their own genetic information (mRNA). Using this technology, both synthetic and natural libraries (representing the repertoire of proteins naturally expressed in a given cell type or tissue source) have been constructed. Due to the in vitro nature of library construction, Phylos libraries are the largest described to date, up to 1014 in size. From a library of such molecules, one can select for a protein function of choice with the benefit that the genetic material is linked to the protein for subsequent PCR amplification, enrichment, and, ultimately, identification. © 2000 John Wiley & Sons, Inc. Med Res Rev, 20, No. 3, 212–215, 2000
Removal of Drug Name From the Table
Journal: JAMA (2018)

Association Between Oxygen Saturation Targeting and Death or Disability in Extremely Preterm Infants in the Neonatal Oxygenation Prospective Meta-analysis Collaboration," 1 published in the June 5, 2018, issue of JAMA, there were data errors in Figure 3 for the row "z score for infant body weight at postmenstrual age of 36 wk" and male and female were transposed in Figure 4.This article was corrected online.
Ehlers-Danlos syndrome and "congenital" arteriovenous fistulae. A clinicopathologic study of a family
Authors: H. T. Lynch
Journal: JAMA (1965)

THE EHLERS-DANLOS syndrome (E-D) is a hereditary disorder of connective tissue wherein the pathogenesis is not clear. The phenotypic expression is exceedingly variable, such that minimally affected individuals may pass as "normal." Because of this, McKusick<sup>1</sup>speculates that E-D may actually be the most common of the heritable connective-tissue disorders. However, in the face of this, many aspects of this syndrome, including cardiovascular and systemic effects, remain to be explained. The purpose of this report is to present a family study of E-D wherein the proband was severely affected and died from rupture of an aneurysm of the thoracic aorta. At autopsy, he was found to have a fistula between the abdominal aorta and the inferior vena cava, as well as between the left common iliac artery and vein. So far as we can determine, this is the first report of E-D showing such fistulae. <h3>Report of a Case</h3>
SOCIETY NEWS.
Journal: JAMA (1896)

<b>The Tippecanoe County (Ind.) Medical</b>Society at its last meeting elected the following officers: President,Dr. R.S.Tea; Vice-President, Dr. B. Wetherill; Secretary, Dr. Geo. F. Keiper; Treasurer, Dr. Geo. F. Beasley; Censors, Drs. G. K. Throckmorton, W. R. Moffit, E. C. Davidson. The laboratories of Purdue University are thrown open to the profession. In the last six weeks Dr. Bitting, of the University, has lectures on experiments with tuberculin on cattle, and Professor Burrage, the sanitarian, on typhoid fever. On March 16, Professor Duff will demonstrate the cathode rays to the society. The society is enjoying a prosperous year. Meetings on the first and third Mondays. <h3>New York State Medical Association.</h3> —The following letter has been issued: Troy, N. Y., Feb. 29, 1896. <h3>Dear Doctor:</h3> —The Twelfth Volume of our Transactions is nearly completed, and will be distributed in the near future. It is fully equal to any of its predecessors.
Irradiation and Anticoagulant Therapy to Prevent Pulmonary Metastases of the V2 Carcinoma in Rabbits
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Autosomal Disorders
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal