tbuckley/cabot-search huggingface dataset:
Analysis of hepatitis B virus quasispecies in circulating viral DNA and RNA: are genotype and complexity different?
Authors: Cristina Godoy Cruz, David Tabernero, Josep Gregori, Marta Vila, Ariadna Rando, Sara Sopena, Maria Francesca Cortese, Rosario Casillas, Marçal Yll, Rafael Esteban, Mar Riveiro Barciela, Maria Buti, Francisco Rodríguez-Frías
Journal: Journal of Hepatology (2020)
Massachusetts Medical Society
Authors: Francis X. Dufault
Journal: New England Journal of Medicine (1966)

Dwight L. Siscoe, M.D. 1889 – 1966The Church of the Redeemer in Chestnut Hill was filled on the afternoon of August 19 when the rector, conducting a simple memorial service for Dwight Siscoe, read from The Prophet of Kahlil Gibran:There are those who give with joy, and that joy is their reward ...They give as in yonder valley the myrtle breathes its fragrance into space.Through the hands of such as these God speaks, and from behind their eyes He smiles upon the earth.Born in Kansas in 1889, Dr. Siscoe received his bachelor's degree from Colorado . . .
THE DISPENSARY WAR.
Journal: JAMA (1898)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Differential Effects of Nephrotoxic Agents on Renal Transport and Metabolism by Use of In Vitro Techniques
Authors: Gerald H. Hirsch
Journal: Environmental Health Perspectives (1976)

A number of studies by the author and other investigators are reviewed in which the in vitro kidney slice technique has been used to evaluate the nephrotoxicity of various compounds. The kidney slice technique can be used to determine the effect of prior drug treatment of laboratory animals on renal organic acid (p-aminohippurate) or organic base (N-methylnicotinamide) transport, on glucose synthesis, and on oxygen consumption by renal coritical slices. The nephrotoxic agents uranyl nitrate and potassium dichromate exert inhibitory effects on renal function, althouhg both agents enhance organic base transport at low doses and potassium dichromate enhances organic acid transport at moderate doses. Enhanced PAH transport has been found to be a sensitive indicator of gentamicin induced nephrotoxicity, while inhibition of other parameters has been reported. The tissue slice method is less effective in evaluation chronic nephrotoxicity such as that produced by lead. The inhibitory effect of mercurial diuretics has been shown to be due to the general depression of metabolic activity by mercury. The kidney slice technique has been found to be a sensitive indicator in the assessment of halogenated hydrocarbon-induced nephrotoxicity. Differential effects of compounds on in vitro organic acid and base trasport provides information about the transport of these compounds as well as about their nephrotoxicity. Although it is often desirable to perform in vivo tests or other in vitro renal function tests, the kidney slice technique has proved to be extremely useful in toxicological evaluations.
COHN—THE CRYPTOGAMIC BOTANIST
Authors: J. H. T.
Journal: JAMA (1961)

Ferdinand Julius Cohn, whose critical natural events—his birth and death—occurred six and three years later than those of Louis Pasteur, is less well known in America than his contemporary. Their scientific accomplishments were closely interwoven. Cohn, a German, and Pasteur, a Frenchman, made major contributions in the field of bacteriology and, by their studies on fermentation and putrefaction, exposed the fallacy of spontaneous generation. Cohn was trained as a cryptogamic botanist (Gr.<i>kryptos</i>, occult;<i>gamos</i>, marriage) and occupied the chair of botany in Breslau. His particular sphere of interest as a cryptogamist concerned bacteria. He founded the<i>Beiträge zur Biologie der Pflanzen</i>. His critical investigations of bacterial classification were published in the 1870's, contemporary with the contributions of Pasteur on the fermentation of wine and beer. The status of bacteriology in 1872 was reviewed by Cohn on the occasion of the second centennial of the discovery of a new world
Norwalk-Like Virus Outbreaks at Two Summer Camps--Wisconsin, June 2001
Journal: JAMA (2001)

On June 27 and 28, 2001, the Wisconsin Division of Public Health was notified by two local health departments of outbreaks of gastroenteritis at two summer recreational camps (camps A and B) in northern Wisconsin. This report summarizes the investigation of these outbreaks, which documents person-to-person transmission of "Norwalk-like virus" (NLV) and underscores the importance of cleaning environmental surfaces and the availability and use of hand-washing facilities at recreational camps.
International Course on Malignant Lymphomas
Journal: JNCI Journal of the National Cancer Institute (1978)

Journal Article International Course on Malignant Lymphomas Get access JNCI: Journal of the National Cancer Institute, Volume 61, Issue 6, December 1978, Page 1547, https://doi.org/10.1093/jnci/61.6.1547-a Published: 01 December 1978
Study questions safety, economic benefits of outpatient tonsil/adenoid surgery
Authors: C. A. Raymond
Journal: JAMA (1986)

"WE'RE ALL becoming cost conscious.... It stands to reason that if patients were to go home two to four hours after surgery, there could be a large savings. But we have to be careful that we don't compromise the patient's health. As our study states, you really should keep them eight hours after surgery, and by that time, there isn't much [cost] difference [involved in] keeping them overnight." Such were the comments of Don E. Gebhart, MD, clinical professor of otolaryngology, Ohio State University College of Medicine, Columbus. He and colleague Jeffrey S. Carithers, MD, resident clinical instructor in otolaryngology at the university, presented evidence to counter current pressure on physicians to discharge tonsilloadenoidectomy (T and A) patients the same day of surgery. Based on an analysis of nearly 3000 T and A procedures, they argue that early discharge may be both hazardous and economically unwarranted. They reported their study
In the Spotlight: Neuroengineering
Authors: Nitish V. Thakor
Journal: IEEE Reviews in Biomedical Engineering (2012)

Considering the high volume of publications and ever increasing attendance at the international conferences, including the 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Conference (IEEE EMBC 2012), Neuroengineering appears to be evolving as an independent discipline by itself. Continuing the legacy of the previous years' conferences, neuroengineering was one of the most represented topics at the IEEE EMBC 2012, held this year in San Diego, CA. Contributing to the interest were three workshops that focused on systems level concepts in neuroengineering: namely, Brain - Machine - Body Interfaces (led by Gert Cauwenberghs, University of California, San Diego), Brain Dynamics in Human Motor Control (led by David Peterson, University of California, San Diego) and Brain-Computer Interfaces and Electrocorticography (led by Robert Prueckl, Guger Technologies). These and other related works are briefly reviewed.
Pelvic Tumour Complicating Pregnancy
Authors: P. Horrocks
Journal: BMJ (1886)

marked, it is true, than was the case four ycars ago, and less, enaily to be mistaken for the speech of her companiion case, but still belong- ing, with her, to a typo wlhich we hiave not met with under other conditions.As the nLervous so(euelte of small-pox have receivedl very little atten- tion in English imiedical literatture, we coultl be sure thley were very uncommon in practice, btit thoughlt it wortli while to tuirn for a moinent to the experience of sotime of the chief small-poxlhospitals of Londoni.The reco)rds at Stockwell were cotnsulted by Dr. Mllyers, anid showed in the last fourteen y-ears about 1,600 deaths from small-pox, but in onily three of these is aniy nervous injury mentioned ; and. in these it was slight cerebral mieningitis, with 11o symptons that couldI clear-ly be distinguished, dluring-life, in the patient's stato of high fever and deliriutmi.Ttie clinical accouuts of the last 2,000 cases were looked througlh wvithout tiiidiing aniy recortds of nervous sequehe.At
Irish Dispensary Doctors
Authors: R. Abraham, J. J. Curran, J. T. Elliott, J. Gordon, R. Gray, J. Keating, H. C. Manley, R. H. Newett, R. D. Patterson, J. Patterson, J. R. Phillips, R. J. Roulston, P. W. Rice, W. J. Shee, H. Warnock
Journal: BMJ (1891)
Clinical Uncertainty
Authors: Chika Uzoigwe, Jonathan Bevan, Farzad Shabani
Journal: JAMA Internal Medicine (2020)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Internal Medicine HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Internal Medicine journal
Related and Unrelated Donor Transplantation for β Thalassemia Major: Results of an International Survey
Authors: Chunfu Li, Vikram Mathews, Biju George, Soyoung Kim, Kyle Hebert, Hua Jiang, Changgang Li, Yiping Zhu, Daniel A Keesler, Rajni Agarwal, Jaap Jan Boelens, Christopher C. Dvorak, Jeffery Auletta, Rakesh Kumar Goyal, Rabi Hanna, Kimberly A. Kasow, David Margolis, Shalini Shenoy, Mark C. Walters, Mary Eapen
Journal: Blood (2018)
Medicinal Foods.
Authors: James B. Herrick
Journal: JAMA (1907)

To the Editor:\p=m-\Iam glad to see the report on medicinal foods in The Journal, May 11.I have long wished for accu- rate proof of the weakness of such foods in nutrient value, for I was firmly convinced their value was low, and such proof is afforded by the table.It is well for those who use them so freely and who so unhesitatingly substitute them for milk and other articles of diet, to study the problem of the calories in these foods as set forth in the report; it is surely instructive.Those who are opposed to the use of alcohol in practice will do well to read this report before they again prescribe
The 1994 JAMA Peer Reviewers
Journal: JAMA (1995)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 4564: Tumor infiltrating lymphocytes are associated with p16 protein expression in acral lentiginous melanoma
Authors: Marco A. Galvez Nino, Miluska Castillo, Luis A. Bernabe, sandro Casavilca, Valeria Villegas, Joselyn Sanchez, Jorge Dunstan, Julio Abugatas, Carlos Castaneda, Henry Gomez
Journal: Cancer Research (2019)

Abstract Background: The loss of function of gene p16(INK4a)/CDKN2 is associated with the development of several neoplasm and tumor progression, likewise, the level of tumor infiltrating lymphocytes is a predictive and prognostic biomarker of survival. This study aims to evaluate the association between composition of tumor infiltrating lymphocytes (TILs) and expression of p16 in acral lentiginous melanoma (ALM), and their impact on prognosis. Materials and methods: A cohort of 148 surgical pathology specimens of ALM was studied. TILs were evaluated by immunohistochemical detection of CD3 and CD8, along with CD20, CD4, CD68, and CD163 in a subset of 43 cases, likewise, we classify the level of TILs in grades by combining density and distribution. p16 protein expression by immunohistochemistry was also investigated in all cases. Results: The median age was 66 years, median Breslow thickness was 6.0 mm, Grade III of TILs was found in 28.4% and lymph nodes were involved in 44.6%. Breslow thickness (p&amp;lt;0.001), stage I-II (p&amp;lt;0.001), negative lymph nodes (p&amp;lt;0.001) and &amp;lt;10% p16 (p&amp;lt;0.001) were associated with longer survival. Grade III of TILs was associated with thinner Breslow thickness (p=0.008) and lower mitosis (p=0.047). A higher density of CD3 TILs was associated with male gender (p=0.008), thinner Breslow thickness (p=0.047), negative lymph node (p=0.031), early stage (p=0.046), and p16 nuclear expression of &amp;gt;10% (p=0.045). Higher CD8 TIL was associated with &amp;gt;p16 (p=0.03). Survival analysis found that longer survival doesn’t associated with high grade of TILs (p=0.094). Levels of CD3+ and CD8+ cells were correlated with those of CD4+, CD20+, CD68+ and CD163+ immune cells. Conclusions: Loss of expression of p16 is associated with lower levels of CD3+ and CD8+ TIL, indicating a probable relationship between p16 and TILs immune response in ALM. Citation Format: Marco A. Galvez Nino, Miluska Castillo, Luis A. Bernabe, sandro Casavilca, Valeria Villegas, Joselyn Sanchez, Jorge Dunstan, Julio Abugatas, Carlos Castaneda, Henry Gomez. Tumor infiltrating lymphocytes are associated with p16 protein expression in acral lentiginous melanoma [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 4564.
Promoting sexual health
Authors: C. Rayner
Journal: BMJ (1992)

The introduction to this issue of AIDS Action draws attention to the importance of the magazine's entire focus on the valuable lessons learned from family planning programs on education or counseling about HIV infections and sexually transmitted diseases (STDs). A broader definition of safe sex is currently being promoted; this definition allows for sex that is pleasurable and safer with regard to unwanted pregnancy, infections, and abuse. Both advice on how to talk to people about sexual activities and training activities for AIDS and family planning workers are included in the various articles. Sexual health is the goal of health and sex education efforts. Promoted are achievement of a state of physical, mental and social well-being about sex and sexuality, avoiding STDs and unwanted pregnancies, and indirectly protection the health of infants. Many family planning and AIDS workers are failing to help people with their sexual lives and need to overcome their prejudices about sexual behavior. It is important to understand what factors influence sexual health and how: contraceptive supply, availability of STD treatment, women's expectations, attitudes towards abortion, or other cultural and religious factors. Workers should be involving people from the community in the development of programs to assure that the community's needs are met. The task may involve changing people's attitudes and beliefs. The urgency of the problems of AIDS and STDs and unwanted pregnancy mandates that sexual health be promoted.
Violence Management in Hospitals
Journal: JAMA (1992)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Plötzliche und akute Erkrankungen des Nervensystems: Ihr Erkennen und ihre Behandlung. Vorlesungen, gehalten vor reiferen Studierenden und Aerzten.
Journal: JAMA (1927)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Marriages
Journal: JAMA (1949)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Digoxin-prescribing. Mostly good news
Authors: M. Weintraub
Journal: JAMA (1979)

We examined digoxin-prescribing in 47,000 prescriptions written predominantly by physicians in a large family medicine practice. Two hundred fifty-four patients received 511 digoxin prescriptions. Dose adjustments for age (16% decrease in patients older than 64 years), for renal disease (33% decrease), and for atrial fibrillation (39% increase) followed good prescribing practices. Appropriately lower loading doses were used for digitalization. However, despite continuing concern over the bioavailability of generic digoxin tablets, less than 40% of digoxin prescriptions in this study were written for the innovator's brand-name product (Lanoxin). (<i>JAMA</i>242:445-448, 1979)
GRANULOMA ANNULARE
Authors: E. O. HALLIWELL, JOHN T. INGRAM
Journal: British Journal of Dermatology (1935)

Journal Article GRANULOMA ANNULARE Get access E. O. HALLIWELL, M.R.C.P.Lond., E. O. HALLIWELL, M.R.C.P.Lond. Skin Department, The General Infirmary, Leeds Search for other works by this author on: Oxford Academic Google Scholar JOHN T. INGRAM, M.D.Lond., M.R.C.P.Lond. JOHN T. INGRAM, M.D.Lond., M.R.C.P.Lond. Skin Department, The General Infirmary, Leeds Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology and Syphilis, Volume 47, Issue 8-9, 1 August 1935, Pages 319–340, https://doi.org/10.1111/j.1365-2133.1935.tb09880.x Published: 01 August 1935