tbuckley/cabot-search huggingface dataset:
Breast Density Does Not Influence Breast Cancer Death Among Breast Cancer Patients
Journal: JNCI Journal of the National Cancer Institute (2012)

Breast Cancer Death Among Breast Cancer Patients the risk of dying from breast cancer was not related to high mammographic breast density in breast cancer patients, according to a study published August 21 in the Journal of the National Cancer Institute.one of the strongest risk factors for non-familial breast cancer is elevated mammographic breast density.While women with elevated mammographic breast density have a higher risk of developing breast cancer, it is not established whether a higher density indicates a lower chance of survival in breast cancer patients.In order to determine if higher mammographic breast density is linked to a reduced survival in breast cancer patients, Gretchen L. Gierach, Ph.D., m.P.h., of the Division of Cancer epidemiology and Genetics (DCeG) at the National Cancer Institute in maryland, and colleagues looked at data from the u.S. Breast Cancer Surveillance Consortium and examined 9,232 women who were diagnosed with primary invasive breast carcinoma between 1996-2005 with an average follow-up of 6.6 years.the researchers studied the relationships between mammographic breast density and risk of death from breast cancer and all causes.mammographic density was measured using the Breast Imaging reporting and Data System (BI-rADS) density classification.the researchers found that density does not influence the risk of death once the disease has developed.they write, "It is reassuring that elevated breast density, a prevalent and strong breast cancer risk factor, was not associated with risk of breast cancer death or death from any cause in this large, prospective study."however, they did find an association between low density and increased risk of breast cancer death among obese patients, or those diagnosed with large or high-grade tumors."one explanation for the increased risks associated with low density among some subgroups is that breasts with a higher percentage of fat may contribute to a tumor microenvironment that facilitates cancer growth and progression," the authors write.they add that these findings highlight the need to further probe "possible interactions between breast density, other patient characteristics, and subsequent treatment in influencing breast cancer prognosis.
Consensus conference. Noise and hearing loss
Journal: JAMA (1990)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Achieving Equity in Lung Cancer Screening for Black Individuals Requires Innovation to Move Beyond “Equal” Guidelines
Authors: Hilary A. Robbins, Rebecca Landy, Jasjit S. Ahluwalia
Journal: JAMA Oncology (2022)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Oncology HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Oncology journal
Book Review Biochemistry in Internal Medicine . By Max Trumper, Ph.D., Clinical Chemist and Toxicologist; formerly in charge of the Laboratories of Biochemistry of the Jefferson Medical College and Hospital and of the Psycho-Biochemistry Laboratory, Graduate School of Medicine, University of Pennsylvania, Philadelphia, and Abraham Cantarow, M.D., Instructor in Medicine, Jefferson Medical College, Assistant Attending Physician, Philadelphia General Hospital; in charge of Laboratory of …
Journal: New England Journal of Medicine (1932)
The Clinical Utility of the Dexamethasone Suppression Test in Psychiatry
Authors: Robert M. A. Hirschfeld
Journal: JAMA (1983)

The dexamethasone suppression test (DST) is being increasingly used in psychiatry, especially in the differential diagnosis of affective disorders. In light of this, the National Institute of Mental Health convened a workshop of clinical scientists drawn from neuroendocrinology, psychopathology, and general clinical psychiatry to review the evidence for the efficacy of the use of the DST in psychiatry. Specifically considered were DST's relevance to differential diagnosis, its use as a predictor of response to treatment, its relationship with other biologic variables, and technical issues. The panelists concluded that at this time there are no clear indications for routine use of the DST in diagnosis or clinical management of depression, although it is a useful research tool. Areas of potential utility include prediction of suicidal activity, prediction of relapse, and differential diagnosis. (<i>JAMA</i>1983;250:2172-2174)
ISRAEL
Journal: JAMA (1961)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Navigating Clinical and Business Ethics While Sharing Patient Data
Authors: Kelly N. Michelson, James G. Adams, Joshua M. M. Faber
Journal: JAMA (2022)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Long-term Neurocognitive Morbidity After a Single Episode of Respiratory Failure in Children
Authors: Steven L. Shein, Alexandre T. Rotta
Journal: JAMA (2022)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Tuberculosis Infection in a Jail
Journal: Annals of Internal Medicine (1999)

Summaries for Patients19 October 1999Tuberculosis Infection in a JailSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-131-8-199910190-00037 SectionsAboutFull Text ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail What is the problem and what is known about it so far?Tuberculosis is an infection that can affect the lungs, among other organs of the body. Tuberculosis infection of the lungs can be very contagious. Tuberculosis is common among people who have been in prison or jail.Why did the researchers do this particular study?The researchers studied an outbreak of tuberculosis in a jail in Memphis, Tennessee. They thought this information might help to find ways to prevent tuberculosis from spreading from one person to another.Who was studied?38 inmates and 5 guards from this jail who ... Author, Article, and Disclosure InformationAffiliations: The summary below is from the full report titled “Transmission of Tuberculosis in a Jail.” It is in the 19 October 1999 issue of Annals of Internal Medicine (volume 131, pages 557-563). The authors are T.F. Jones, A.S. Craig, S.E. Valway, C.L. Woodley, and W. Schaffner.Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. The summaries may be reproduced for not-for-profit educational purposes only. Any other uses must be approved by the American College of Physicians-American Society of Internal Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoTransmission of Tuberculosis in a Jail Timothy F. Jones , Allen S. Craig , Sarah E. Valway , Charles L. Woodley , and William Schaffner Metrics 19 October 1999Volume 131, Issue 8Page: 557KeywordsDNAGenetic fingerprintingLungsResearch laboratoriesTuberculosis ePublished: 15 August 2000 Issue Published: 19 October 1999 Copyright & PermissionsCopyright © 1999 by American College of Physicians. All Rights Reserved.Loading ...
AB0334 Musculoskeletal ultrasonography assists the diagnostic performance of the 2010 classification criteria for rheumatoid arthritis
Authors: S.-Y. Kawashiri, T.S. Suzuki, A. Okada, S. Yamasaki, M. Tamai, H. Nakamura, T. Origuchi, M. Uetani, K. Aoyagi, K. Eguchi, A. Kawakami
Journal: Annals of the Rheumatic Diseases (2013)

<h3>Background</h3> Recent imaging modalities such as musculoskeletal ultrasonography (MSKUS) and magnetic resonance imaging (MRI) are known to detect joint injury very frequently in early arthritis patients. <h3>Objectives</h3> To investigate whether MSKUS assists the diagnostic performance of the 2010 rheumatoid arthritis (RA) classification criteria comparing its usefulness with plain MRI. <h3>Methods</h3> Sixty-nine early arthritis patients were consecutively enrolled from May 2010 through February 2011. None of the patients had beentreated with disease-modifying antirheumatic drugs (DMARDs) including biologics or glucocorticoids. In MSKUS of bilateral wrist and finger joints including the 1st–5th metacarpophalangeal (MCP) joints, the 1st interpharangeal (IP) joint and the 2nd–5th proximal interpharangeal(PIP)joints, the findings obtained by gray scale (GS) and power Doppler (PD) assessment were graded on a semi-quantitative scale from 0 to 3. Plain MRI of both wrist and finger joints was also examined. The diagnosis of RA was defined by the initiation of DMARDs within the first 3 months. The diagnostic performanceof the patients was evaluated at entry using the 2010 RA classification criteria in conjunction with MSKUS or MRI. <h3>Results</h3> The mean disease duration, age, prevalence of RF and anti-cyclic citrullinated peptide antibodies (ACPA) at examination were 3.9 months, 54 years-old, 46.3% and 36.2%, respectively. The 2010 RA classification criteria classified RA at a sensitivity of 59.5%, a specificity of 87.5%, and a positive predictive value (PPV) of 84.6%. The best MSKUS finding for differentiating RA was the presence of a PD grade ≥2 that was superior to MRI-proven osteitis. We have proposed that the decision tree algorithm of the 2010 RA classification criteria with a PD grade ≥2 reveals the best discriminative ability. <h3>Conclusions</h3> MSKUS, especially with a strong PD signal, is very useful to assist the diagnostic performance of the 2010 RA classification criteriain the early recognition of RA. <h3>References</h3> Kawashiri SY, et al. The power Doppler ultrasonography score from 24 synovial sites or 6 simplified synovial sites, including the metacarpophalangeal joints, reflects the clinical disease activity and level of serum biomarkers in patients with rheumatoid arthritis. Rheumatology (Oxford) 2011; 50: 962-5. <h3>Disclosure of Interest</h3> None Declared
Simulated Cost-effectiveness and Long-term Clinical Outcomes of Addiction Care and Antibiotic Therapy Strategies for Patients With Injection Drug Use–Associated Infective Endocarditis
Authors: Joëlla W. Adams, Alexandra Savinkina, James C. Hudspeth, Mam Jarra Gai, Raagini Jawa, Laura R. Marks, Benjamin P. Linas, Alison Hill, Jason Flood, Simeon Kimmel, Joshua A. Barocas
Journal: JAMA Network Open (2022)

Emerging evidence supports the use of outpatient parenteral antimicrobial therapy (OPAT) and, in many cases, partial oral antibiotic therapy for the treatment of injection drug use-associated infective endocarditis (IDU-IE); however, long-term outcomes and cost-effectiveness remain unknown.
Length of hospital stay and risk of intensive care admission and in-hospital death among COVID-19 patients in Norway: a register-based cohort study comparing patients fully vaccinated with an mRNA vaccine to unvaccinated patients
Authors: Robert Whittaker, Anja Bråthen Kristofferson, Beatriz Valcarcel Salamanca, Elina Seppälä, Karan Golestani, Reidar Kvåle, Sara Viksmoen Watle, Eirik Alnes Buanes
Journal: Clinical Microbiology and Infection (2022)

We estimated the length of stay (LoS) in hospital and the intensive care unit (ICU) and risk of admission to ICU and in-hospital death among COVID-19 patients ≥18 years in Norway who had been fully vaccinated with an mRNA vaccine (at least two doses or one dose and previous SARS-CoV-2 infection), compared to unvaccinated patients.Using national registry data, we analyzed SARS-CoV-2-positive patients hospitalized in Norway between 1 February and 30 November 2021, with COVID-19 as the main cause of hospitalization. We ran Cox proportional hazards models adjusting for vaccination status, age, sex, county of residence, regional health authority, date of admission, country of birth, virus variant, and underlying risk factors.We included 716 fully vaccinated patients (crude overall median LoS: 5.2 days; admitted to ICU: 103 (14%); in-hospital death: 86 (13%)) and 2487 unvaccinated patients (crude overall median LoS: 5.0 days; admitted to ICU: 480 (19%); in-hospital death: 102 (4%)). In adjusted models, fully vaccinated patients had a shorter overall LoS in hospital (adjusted log hazard ratios (aHR) for discharge: 1.61, 95% CI: 1.24-2.08), shorter LoS without ICU (aHR: 1.27, 95% CI: 1.07-1.52), and lower risk of ICU admission (aHR: 0.50, 95% CI: 0.37-0.69) compared to unvaccinated patients. We observed no difference in the LoS in ICU or in risk of in-hospital death between fully vaccinated and unvaccinated patients.Fully vaccinated patients hospitalized with COVID-19 in Norway have a shorter LoS and lower risk of ICU admission than unvaccinated patients. These findings can support patient management and ongoing capacity planning in hospitals.
Adipocytokines in Synovial Fluid
Authors: Diego Ize-Ludlow, Sean Ragone, Jeffrey Bernstein, Michael Duchowny, Barbara Pen ˜a
Journal: JAMA (2004)

Analysis by LC-MS of the sesquiterpene lactone fraction of each sample was performed to determine the presence of anisatin, neoanisatin, and veranisatins A, B, and C. Anistatin and neoanisatin are potent neurotoxins found in I anisatum. 4Although I verum is considered safe for consumption, this species also contains the toxic compounds, veranisatin A, B, and C. 7 Anisatin compounds are thought to act as picrotoxin-like noncompetitive ␥-aminobutyric acid (GABA) antagonists. 8The mass spectral pattern of each sample was similar in the number, type, and concentration of these compounds.Extracts from the third case, however, suggested the presence of an Illicium species other than I verum.Comment.Given our laboratory findings, the symptoms we have described may be attributed to an overdose of I verum, contamination with I anisatum, or a combination of both.Illicium verum has been considered safe because it contains veranisatins in low concentrations. 7However, relatively small quantities in infants may be sufficient to produce adverse neurologic reactions. 9ngestion of star anise should be considered in the differential diagnosis of infants presenting with acute-onset irritability, vomiting, and seizures.Based on these cases and the finding of I verum contamination, we recommend against administering star anise to infants.Stricter regulation may also be warranted.
Metabolism, New York
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Consultant surgeons and vasectomy.
Authors: V Harrison, G Peat
Journal: BMJ (1973)

Mean Milk pH and Colony Counts of Specific E. coli Milk Count after Incubation (organisms/ml) Group pH 1 hour 2 hours 3 hours 4 hours 5 hours 6 hours I 6-58 5-1 x 103 9.3 x 103 4-6 x 104 8-6 x 10' 5-3 x 10' 3 x 10' II 7-20 5 x 103 8 x 103 3 x 10' 7 x 104 1-6 x 10 4-6 x 10' III 7.40 3 x 10' 5 x 10' 9-3 x 103 2 x 104 4-6 x 10' 7-8 x 104 P (Group I & II) >0 1 <0-02 <0 05 <0 05 <0 01 <0 01 P (Group I & III) >0 1 <0 01 <0.01 <0 01 <0 01 <0.01water was added to untitrated samples.Viable E. coli counts were made on 6 mnl of milk at the reconstituted pH and at pH values of 7-20 and 7.40.The specific E. coli 011/B4 inoculum was prepared from a 12- hour actively growing culture in tryptone water.Each milk sample was inoculated with approximately 2 X 102 organisms and in- cubated for six hours at 37°C.Counts were made hourly in triplicate on blood agar plates by the method of Bullen et al.1The results shown in the table indicate a bacteriostatic effect of titrated milik which is more marked after six hours and most obvious at a pH of 7-40.The bacteriostatic effect appears to be pH-related as it was originally produced in milk after an addition of electrolyte-free THAM (trometamol) as well as sodium bicarbonate.We trust that the disagreement regarding these findings will not detract from the main point of the original article-namely, that the ability of titrated milk to colonize an infant's bowel with lactobacilli rather than E. coli may provide some protection against gastro- enteritis.-Weare, etc.