tbuckley/cabot-search huggingface dataset:
Integration of multiple imaging platforms to uncover cardiovascular defects in adult zebrafish
Authors: Anabela Bensimon-Brito, Giulia L M Boezio, João Cardeira-da-Silva, Astrid Wietelmann, Srinath Ramkumar, Pia R Lundegaard, Christian S M Helker, Radhan Ramadass, Janett Piesker, Arno Nauerth, Clemens Mueller, Didier Y R Stainier
Journal: Cardiovascular Research (2021)

Abstract Aims Mammalian models have been instrumental in investigating adult heart function and human disease. However, electrophysiological differences with human hearts and high costs motivate the need for non-mammalian models. The zebrafish is a well-established genetic model to study cardiovascular development and function; however, analysis of cardiovascular phenotypes in adult specimens is particularly challenging as they are opaque. Methods and results Here, we optimized and combined multiple imaging techniques including echocardiography, magnetic resonance imaging, and micro-computed tomography to identify and analyse cardiovascular phenotypes in adult zebrafish. Using alk5a/tgfbr1a mutants as a case study, we observed morphological and functional cardiovascular defects that were undetected with conventional approaches. Correlation analysis of multiple parameters revealed an association between haemodynamic defects and structural alterations of the heart, as observed clinically. Conclusion We report a new, comprehensive, and sensitive platform to identify otherwise indiscernible cardiovascular phenotypes in adult zebrafish.
The interplay between gut bacteria and the yeast <i>Candida albicans</i>
Authors: J. Christian Pérez
Journal: Gut Microbes (2021)

The fungus Candida albicans is a ubiquitous member of the human gut microbiota. Hundreds or thousands of bacterial taxa reside together with this fungus in the intestine, creating a milieu with myriad opportunities for inter-kingdom interactions. Indeed, recent studies examining the broader composition – that is, monitoring not only bacteria but also the often neglected fungal component – of the gut microbiota hint that there are significant interdependencies between fungi and bacteria. Gut bacteria closely associate with C. albicans cells in the colon, break down and feed on complex sugars decorating the fungal cell wall, and shape the intestinal microhabitats occupied by the fungus. Peptidoglycan subunits released by bacteria upon antibiotic treatment can promote C. albicans dissemination from the intestine, seeding bloodstream infections that often become life-threatening. Elucidating the principles that govern the fungus-bacteria interplay may open the door to novel approaches to prevent C. albicans infections originating in the gut.
1243P Cumulative incidence and metastatic patterns of relapsed vs de novo stage IV non-small cell lung cancer (NSCLC) characterized by histology and EGFR status
Authors: E. Strom, S. Schmid, M. Garcia, S. Cheng, L.J. Zhan, M.C. Brown, K. Khan, P. Walia, A. Sabouhanian, M.T. Chowdhury, J. Herman, D. Patel, N. Leighl, P. Bradbury, F.A. Shepherd, A. Sacher, W. Xu, D. Shultz, G. Liu
Journal: Annals of Oncology (2021)
234P Effect of palbociclib (PAL) + endocrine therapy (ET) on time to chemotherapy (TTC) across subgroups of patients (pts) with hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2-) advanced breast cancer (ABC): Post hoc analyses from PALOMA-2 (P2) and PALOMA-3 (P3)
Authors: H.S. Rugo, S-A. Im, A.A. Joy, S. Yaroslav, J.M. Walshe, B. Sleckman, S. Loi, K. Puyana Theall, S. Kim, X. Huang, E. Bananis, R. Mahtani, R.S. Finn, V. Diéras
Journal: Annals of Oncology (2021)
314P Efficacy of taxane rechallenge in early metastatic relapse of HER2-negative breast cancer patients previously treated with taxane
Authors: A. Vasseur, M. Carton, S. Guiu, P. Augereau, L. Uwer, M.A. Mouret Reynier, C. Levy, J-C. Eymard, A. Gonçalves, M. Robert, T. De La Motte Rouge, T. Bachelot, T. Petit, M. Debled, T. Grinda, I. Desmoulins, L. Vanlemmens, F. Dalenc, G. Simon, L. Cabel
Journal: Annals of Oncology (2021)
Ancestral human mother–infant interaction was an adaptation that gave rise to music and dance
Authors: Ellen Dissanayake
Journal: Behavioral and Brain Sciences (2021)

Abstract Human infants are born ready to respond to affiliative signals of a caretaker's face, body, and voice. This ritualized behavior in ancestral mothers and infants was an adaptation that gave rise to music and dance as exaptations for promoting group ritual and other social bonding behaviors, arguing for an evolutionary relationship between mother and infant bonding and both music and dance.
1795P Gender difference in side effects of immunotherapy: A possible clue to optimize cancer treatment
Authors: R. Miceli, H. Eriksson, A.J. Eustace, G. Lo Russo, J. Ballot, C. Bergamini, M.M. Bjaanæs, F. Corti, L. De Cecco, L. Frisardi, P. Giannatempo, E. Verzoni, A. Helland, J.P. Crown
Journal: Annals of Oncology (2021)
83P Evaluation of concordance between PD-L1 immunohistochemistry 28-8 and 22C3 pharmDx assays in metastatic urothelial carcinoma (mUC) in PIVOT-10
Authors: A.O. Siefker-Radtke, U. Hoch, Y. Loriot, A.V. Balar, M.A. Bilen, N.M. Tannir, D.C. Cho, A. Choudhury, D. Chien, D. Yu, S.L. Currie, J. Novotny, L. Santiago, M.A. Tagliaferri, J. Zalevsky, R.A. Huddart
Journal: Annals of Oncology (2021)
302P Clinical implication of tissue re-biopsy in metastatic breast cancer (MBC) patients: A single centre retrospective analysis
Authors: F. Carlino, A. Diana, M. Terminiello, A. Ventriglia, A. Piccolo, V. Bruno, L. Lobianco, M. Caterino, F. Ciardiello, B. Daniele, M. Orditura
Journal: Annals of Oncology (2021)
LBA19 A multicenter, randomized, double-blind, phase II study to evaluate the tolerability of an induction dose escalation of everolimus in patients with metastatic breast cancer (mBC) (DESIREE)
Authors: S. Loibl, M. Schmidt, K. Lübbe, T. Decker, M. Thill, L. Bauer, V. Müller, T. Link, J. Furlanetto, S. Kümmel, C. Mundhenke, O. Hoffmann, M-O. Zahn, L. Müller, C. Denkert, M. van Mackelenbergh, P.A. Fasching, N. Burchardi, V. Nekljudova
Journal: Annals of Oncology (2021)
293P Exploring the interplay between tumor burden and liquid biopsy longitudinal evaluation in hormone receptor-positive, HER2-negative metastatic breast cancer (MBC)
Authors: R. Mazzeo, L. Bortot, A. Michelotti, S. Buriolla, L. Palmero, A. Franzoni, E. Bertoli, G. Targato, L. Allegri, L. Da Ros, M. Alberti, P. Di Nardo, M. Bonotto, S. Sodde, B. Belletti, S. Spazzapan, G. Baldassarre, G. Damante, L. Gerratana, F. Puglisi
Journal: Annals of Oncology (2021)
516MO Phase I/II study of eprenetapopt (APR-246) in combination with pembrolizumab in patients with solid tumor malignancies
Authors: H. Park, G. Shapiro, X. Gao, A. Mahipal, J.S. Starr, M. Furqan, P. Singh, A. Ahrorov, D. Hickman, P. Gallacher, E. Attar, M. Awad, S. Das, E.E. Ileana Dumbrava
Journal: Annals of Oncology (2021)
PTEN mutations in autism spectrum disorder and congenital hydrocephalus: developmental pleiotropy and therapeutic targets
Authors: Tyrone DeSpenza, Marina Carlson, Shreyas Panchagnula, Stephanie Robert, Phan Q. Duy, Nell Mermin-Bunnell, Benjamin C. Reeves, Adam Kundishora, Aladine A. Elsamadicy, Hannah Smith, Jack Ocken, Seth L. Alper, Sheng Chih Jin, Ellen J. Hoffman, Kristopher T. Kahle
Journal: Trends in Neurosciences (2021)
164P Effect of ELOVL5 expression on breast cancer development
Authors: T.L.V. Kieu, L. Pierre, S. Perrey, V. Derangere, C. Truntzer, A. Jalil, A. Dumont, D. Masson, C. Thomas, F. Ghiringhelli, M. Rialland
Journal: Annals of Oncology (2021)
Abstract 18983: Development of Homology-directed Repair-mediated Genome Replacement Targeting Pathological Mutation in Cardiomyocytes
Authors: Shuichiro Higo, Takamaru Ishizu, Yuki Masumura, Tomoaki Higo, Sachio Morimoto, Seiji Takashima, Shungo Hikoso, Yasushi Sakata
Journal: Circulation (2017)

Introduction: Genetic abnormalities are widely recognized as one of the major etiological basis of cardiomyopathy. CRISPR/Cas9 genome editing technology is increasingly recognized as a potential to...
Trends in clinical development of pediatric cancer for PD-1 and PD-L1 inhibitors: an analysis of ClinicalTrials.gov
Authors: Yi Que, Yang Hu, Dongchun Hong, Yizhuo Zhang
Journal: Journal for ImmunoTherapy of Cancer (2021)

Compared with cytotoxic chemotherapy, radiotherapy, and surgery, positive findings have been acquired through the approach of blocking the programmed cell death protein 1 (PD-1) pathway with antibodies that exert inhibitory effects on PD-1 or cell death protein ligand 1 (PD-L1). Results from clinical trials showed great potential in adult patients with cancers, such as melanoma, non-small cell carcinoma, and nasopharyngeal carcinoma. However, studies of checkpoint inhibitors specifically targeting PD-1/PD-L1 in pediatric patients are limited. We evaluated ongoing clinical trials using PD-1 or PD-L1 inhibitors alone or in combination with other therapies to treat pediatric cancer. The proportion of PD-1/PD-L1 combination clinical trials has increased since 2018; the three most common trials over the past 2 years used CTLA-4 monoclonal antibodies, chemotherapy, and therapies that target the vascular endothelial growth factor axis. This commentary aimed to provide trends and specific insights into methods for conducting clinical trials of immunotherapy in the pediatric population.
Anti-CCL-2 / MCP-1 (monocyte chemoattractant protein-1) monoclonal antibodies effectively inhibit tumor angiogenesis and growth of human breast carcinoma
Authors: Prabakaran Kesavan, Francis McCabe, Hillary Millar, Nicole Stowell, Don Griswold, Anuk Das, Marian T. Nakada, Li Yan
Journal: Cancer Research (2005)

1090  C-C chemokine ligand-2 (CCL-2), otherwise known as monocyte chemoattractant protein-1 (MCP-1) is a potent chemoattractant of monocytes that has recently been indicated to play a pivotal role in tumor angiogenesis and growth. In a number of cancer types, including breast cancer, squamous cell carcinoma of head and neck, gastric carcinoma, and hemangioma, CCL-2 expression levels in the primary tumor correlate with blood vessel density, disease staging and prognosis. It has been postulated that CCL-2 recruits tumor-infiltrating macrophages and activates these infiltrating cells to produce angiogenic growth factors such as vascular endothelial growth factor (VEGF) and interleukin-8. These factors in turn stimulate tumor angiogenesis and contribute to cancer disease progression. We explored the role of CCL-2 in tumor angiogenesis in an in vivo angiogenesis model employing human breast cancer cells expressing different levels of CCL-2. Matrigel plugs containing MDA-MB-435S or MDA-MB-231 human breast cancer cells, which secrete 6000 pg/ml/10E6 cells/24 hr and 30 pg/ml/10E6 cells/24 hr CCL-2 in vitro respectively, were implanted subcutaneously (s.c.) in nude mice. Hemoglobin levels in the Matrigel plugs were measured to determine the degree of angiogenic response elicited by the tumor cells. The potency of angiogenic response induced by the two cancer cell lines correlated well with CCL-2 production levels in these cells, supporting the hypothesis that CCL-2 is an angiogenic mediator. The in vivo angiogenic potential of MDA-MB-435S cells was dose-dependently inhibited by anti-CCL-2 monoclonal antibodies, despite the complexity and redundancy of angiogenic growth factors produced by these tumor cells. Furthermore, we explored the tumor inhibitory effect of blocking CCL-2 bioactivity on xenograft human breast cancer models in nude and SCID mice. Prophylactic and early treatment with anti-human CCL-2 antibody in combination with anti-mouse JE antibody significantly inhibited MDA-MB-435S-GFP xenograft human breast tumor growth in nude and SCID mice. A significant reduction in tumor burden was seen in the anti-CCL-2 treated animals compared to the PBS-treated or control IgG-treated animals (p
Shortages of rheumatoid arthritis drugs hit Europe after demand surges for treating covid
Authors: Gareth Iacobucci
Journal: BMJ (2021)

European countries are reporting worsening shortages of anti-inflammatory drugs used to treat arthritis, vasculitis, and other inflammatory rheumatoid and musculoskeletal diseases because they are being repurposed to treat covid-19.

Many such anti-inflammatory and immunosuppressant drugs, including glucocorticoids such as dexamethasone and tocilizumab, a humanised monoclonal antibody, have been used to treat patients with severe covid during the pandemic.

The European Alliance of Associations for Rheumatology (EULAR) has received reports that the surge in use has led to shortfalls of tocilizumab in several countries, including Germany, Portugal, Belgium, and Scandinavian countries.1 Other European countries, including the UK and France, said they were aware of recent concerns about tocilizumab supplies but had not reported actual shortages as yet.

Australia …
1105P Predictive factors of adverse events onset in GEPNET patients treated with PRRT
Authors: F. Scalorbi, G. Argiroffi, A. Lorenzoni, M. Baccini, L. Gherardini, V. Fuoco, N. Prinzi, S. Pusceddu, G. Calareso, E. Garanzini, G. Centonze, M. Milione, C. Chiesa, E. Seregni, M. Maccauro
Journal: Annals of Oncology (2021)
1582P Thromboembolic disease in COVID-19 cancer patients: Impact on overall survival and prognostic factors
Authors: A. Pertejo, S. Martinez Recio, D. Jimenez-Bou, J. Peña-Lopez, I. Ruiz-Gutierrez, G. Martín-Montalvo Pérez, A. Rueda-Lara, V. Martinez Marin
Journal: Annals of Oncology (2021)
Whole-genome sequencing for surveillance of tuberculosis drug resistance and determination of resistance level in China
Authors: Dongxin Liu, Fei Huang, Guoliang Zhang, Wencong He, Xichao Ou, Ping He, Bing Zhao, Baoli Zhu, Fei Liu, Zhiyuan Li, Chunfa Liu, Hui Xia, Shengfen Wang, Yang Zhou, Timothy M Walker, Lei Liu, Derrick W Crook, Yanlin Zhao
Journal: Clinical Microbiology and Infection (2021)
Launching the Antibiotic Era: Personal Accounts of the Discovery and Use of the First Antibiotics
Journal: Annals of Internal Medicine (1991)

Interest in the nature and functioning of research groups is, of course, not new.Gerald Geison's account of Michael Foster's Cambridge Physiology School remains the most accomplished elaboration, to date, of J. B. Morrell's earlier attempt to construct a model to explain the success or failure of individual "schools".Like Morrell, Fruton begins here with Liebig's group at Giessen, before going on to analyse other prominent German chemical and biochemical research groups in the period 1830-1914.Particular attention is focused on the groups of Felix Hoppe-Seyler, Willy Kiihne, and Franz Hofmeister in biochemistry, and on Adolf von Baeyer and Emil Fischer in chemistry.Biographical details of each leader's 'scientific progeny" fill seven appendices.Together with a bibliography
21P COVID-19 cancer patients and thromboembolic disease: Survival analysis
Authors: A. Pertejo-Fernandez, S. Martínez-Recio, D. Jiménez-Bou, J. Peña-López, I. Ruiz-Gutiérrez, G. Martín-Montalvo Pérez, A. Rueda-Lara, V. Martínez-Marín
Journal: Annals of Oncology (2021)
1523MO Initial active surveillance strategy for patients with peripheral sporadic desmoids: A multicentre phase II observational trial
Authors: S. Bonvalot, L. Lam, A. Le Cesne, N. Penel, J-Y. Blay, A. Michot, C.M. Chevreau, P. Anract, D. Waast, S. Piperno-Neumann, F. Duffaud, K. Malekzadeh, C. Honoré, C. Le Pechoux, N. Cozic
Journal: Annals of Oncology (2021)
1085P Ph I/II study of PI3K-β inhibitor GSK2636771 (G771) in combination with pembrolizumab (P) in patients (pts) with PTEN loss and melanoma or other advanced solid tumors
Authors: E. Burton, E.E. Ileana Dumbrava, W. Peng, D. Milton, R. Amaria, J. Mcquade, I.C. Glitza, D. Hong, S. Patel, J. Rodon, T.A. Yap, A. Naing, S.A. Piha-Paul, G. Balmes, A. Lazar, F. Meric-Bernstam, P. Hwu, M.A. Davies, H.A. Tawbi
Journal: Annals of Oncology (2021)
519MO Concordance analysis of treatment recommendations between central consensus and multidisciplinary tumor boards
Authors: H. Kage, K. Sunami, Y. Naito, T. Amano, D. Ennishi, M. Imai, M. Kanai, H. Kenmotsu, K. Komine, T. Koyama, Maeda T., S. Morita, Y. Saigusa, D. Sakai, T. Yamanaka, S. Kohsaka, K. Tsuchihara, T. Yoshino
Journal: Annals of Oncology (2021)
A commentary on “ASA-ECOG as a combined tool for peri-operative risk stratification in COVID-19 survivors – A step towards optimizing healthcare resource utilization” (Int J Surg 2021, July:106062)
Authors: Laura Zharick Ortega Quiroga, María Camila Castellanos Villabona, María Camila Navarro Mansilla, Gonzalo Andrés Domínguez-Alvarado
Journal: International Journal of Surgery (2021)
449P Homologous recombination repair gene mutations predict the efficacy of immune checkpoint inhibitors therapy in colorectal cancer
Authors: Y. Lin, J. Zhang, X. Liao, Y. Zhang, M. Luo, Q. Li, M. Xie, C. Liang, S. Liao, Y. Zheng, X. Hu, M. Huang, R. Liang, Y. Li
Journal: Annals of Oncology (2021)
Author Correction: Ultrasensitive detection of circulating tumour DNA via deep methylation sequencing aided by machine learning
Authors: Naixin Liang, Bingsi Li, Ziqi Jia, Chenyang Wang, Pancheng Wu, Tao Zheng, Yanyu Wang, Fujun Qiu, Yijun Wu, Jing Su, Jiayue Xu, Feng Xu, Huiling Chu, Shuai Fang, Xingyu Yang, Chengju Wu, Zhili Cao, Lei Cao, Zhongxing Bing, Hongsheng Liu, Li Li, Cheng Huang, Yingzhi Qin, Yushang Cui, Han Han-Zhang, Jianxing Xiang, Hao Liu, Xin Guo, Shanqing Li, Heng Zhao, Zhihong Zhang
Journal: Nature Biomedical Engineering (2021)
Domestication Shapes Recombination Patterns in Tomato
Authors: Roven Rommel Fuentes, Dick de Ridder, Aalt D J van Dijk, Sander A Peters
Journal: Molecular Biology and Evolution (2021)

Meiotic recombination is a biological process of key importance in breeding, to generate genetic diversity and develop novel or agronomically relevant haplotypes. In crop tomato, recombination is curtailed as manifested by linkage disequilibrium decay over a longer distance and reduced diversity compared with wild relatives. Here, we compared domesticated and wild populations of tomato and found an overall conserved recombination landscape, with local changes in effective recombination rate in specific genomic regions. We also studied the dynamics of recombination hotspots resulting from domestication and found that loss of such hotspots is associated with selective sweeps, most notably in the pericentromeric heterochromatin. We detected footprints of genetic changes and structural variants, among them associated with transposable elements, linked with hotspot divergence during domestication, likely causing fine-scale alterations to recombination patterns and resulting in linkage drag.
Global properties of regulatory sequences are predicted by transcription factor recognition mechanisms
Authors: Zain M. Patel, Timothy R. Hughes
Journal: Genome biology (2021)

Mammalian genomes contain millions of putative regulatory sequences, which are delineated by binding of multiple transcription factors. The degree to which spacing and orientation constraints among transcription factor binding sites contribute to the recognition and identity of regulatory sequence is an unresolved but important question that impacts our understanding of genome function and evolution. Global mechanisms that underlie phenomena including the size of regulatory sequences, their uniqueness, and their evolutionary turnover remain poorly described.Here, we ask whether models incorporating different degrees of spacing and orientation constraints among transcription factor binding sites are broadly consistent with several global properties of regulatory sequence. These properties include length, sequence diversity, turnover rate, and dominance of specific TFs in regulatory site identity and cell type specification. Models with and without spacing and orientation constraints are generally consistent with all observed properties of regulatory sequence, and with regulatory sequences being fundamentally small (~ 1 nucleosome). Uniqueness of regulatory regions and their rapid evolutionary turnover are expected under all models examined. An intriguing issue we identify is that the complexity of eukaryotic regulatory sites must scale with the number of active transcription factors, in order to accomplish observed specificity.Models of transcription factor binding with or without spacing and orientation constraints predict that regulatory sequences should be fundamentally short, unique, and turn over rapidly. We posit that the existence of master regulators may be, in part, a consequence of evolutionary pressure to limit the complexity and increase evolvability of regulatory sites.
176P Pathological complete response to neoadjuvant systemic therapy in 1160 initial and locally advanced breast cancer patients: Real life data on outcomes
Authors: M.C. Tavares, L. Leite, M. Cesca, F. Campos, D. Santana, E. Saldanha, P. Guimarães, D. Sá, M.F. Simões, R. Viana, S. Loose, F. Rocha, S. Silva, R. Piroll, C. Fogassa, N. Pondé, S.M. Sanches, C. Toledo, F. Makdissi, V.C.C. Lima
Journal: Annals of Oncology (2021)
Global trends in aquatic animal tracking with acoustic telemetry
Authors: Jordan K. Matley, Natalie V. Klinard, Ana P. Barbosa Martins, Kim Aarestrup, Eneko Aspillaga, Steven J. Cooke, Paul D. Cowley, Michelle R. Heupel, Christopher G. Lowe, Susan K. Lowerre-Barbieri, Hiromichi Mitamura, Jean-Sébastien Moore, Colin A. Simpfendorfer, Michael J.W. Stokesbury, Matthew D. Taylor, Eva B. Thorstad, Christopher S. Vandergoot, Aaron T. Fisk
Journal: Trends in Ecology & Evolution (2021)

Acoustic telemetry (AT) is a rapidly evolving technique used to track the movements of aquatic animals. As the capacity of AT research expands it is important to optimize its relevance to management while still pursuing key ecological questions. A global review of AT literature revealed region-specific research priorities underscoring the breadth of how AT is applied, but collectively demonstrated a lack of management-driven objectives, particularly relating to fisheries, climate change, and protection of species. In addition to the need for more research with direct pertinence to management, AT research should prioritize ongoing efforts to create collaborative opportunities, establish long-term and ecosystem-based monitoring, and utilize technological advancements to bolster aquatic policy and ecological understanding worldwide.
Guanidinylated Apolipoprotein C3 (ApoC3) Associates with Kidney and Vascular Injury
Authors: Stefan J. Schunk, Juliane Hermann, Tamim Sarakpi, Sarah Triem, Michaela Lellig, Eunsil Hahm, Stephen Zewinger, David Schmit, Ellen Becker, Julia Möllmann, Michael Lehrke, Rafael Kramann, Peter Boor, Peter Lipp, Ulrich Laufs, Winfried März, Jochen Reiser, Joachim Jankowski, Danilo Fliser, Thimoteus Speer, Vera Jankowski
Journal: Journal of the American Society of Nephrology (2021)

Coexistent CKD and cardiovascular diseases are highly prevalent in Western populations and account for substantial mortality. We recently found that apolipoprotein C-3 (ApoC3), a major constituent of triglyceride-rich lipoproteins, induces sterile systemic inflammation by activating the NOD-like receptor protein-3 (NLRP3) inflammasome in human monocytes via an alternative pathway.
848P Efficacy and safety of pomalidomide and dexamethasone (Pd) for Chinese patients (pts) with relapsed or refractory multiple myeloma (RRMM): A multicenter, single-arm, phase II study
Authors: J. Lu, W-J. Fu, Y-F. Wang, H-G. Zhao, T. Niu, B-J. Fang, A-J. Liao, H. Bai
Journal: Annals of Oncology (2021)
1260P Clinical outcomes of patients with BRAFv⁶⁰⁰-mutated metastatic NSCLC (mNSCLC) receiving first-line (1L) dabrafenib-trametinib vs other standard of care in real-world practice
Authors: B. Melosky, S.M. Knoll, I.S. Souef, W-H. Wu, W.C. Rhodes, J. Martinalbo, F. Ye
Journal: Annals of Oncology (2021)