Effectiveness and Safety of Direct Oral Anticoagulants Versus Warfarin in Patients With Valvular Atrial Fibrillation
Authors: Ghadeer K. Dawwas, Geoffrey D. Barnes, Adam Cuker, James D. Lewis
Journal: Annals of Internal Medicine (2021)

LettersOctober 2021Effectiveness and Safety of Direct Oral Anticoagulants Versus Warfarin in Patients With Valvular Atrial FibrillationGhadeer K. Dawwas, MSc, MBA, PhD, Geoffrey D. Barnes, MD, MSc, Adam Cuker, MD, MS, James D. Lewis, MD, MSCEGhadeer K. Dawwas, MSc, MBA, PhDPerelman School of Medicine and Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PennsylvaniaSearch for more papers by this author, Geoffrey D. Barnes, MD, MScUniversity of Michigan, Ann Arbor, MichiganSearch for more papers by this author, Adam Cuker, MD, MSPerelman School of Medicine, University of Pennsylvania, Philadelphia, PennsylvaniaSearch for more papers by this author, James D. Lewis, MD, MSCEPerelman School of Medicine and Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PennsylvaniaSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/L21-0565 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE: We thank Dr. Rodwin, Dr. Mansi and colleagues, and Drs. Shah and Garg for their interest in our work and appreciate their comments. Although the issue of defining valvular AF is relevant, the definition has evolved and differs slightly across practice guidelines. For example, in 2001, the American College of Cardiology/American Heart Association/European Society of Cardiology guidelines defined nonvalvular AF as AF that occurs in the absence of rheumatic mitral valve disease or a prosthetic heart valve (1). The 2012 focused update of the European Society of Cardiology guidelines for the management of AF defined valvular AF as ...References1. Fuster V, Rydén LE, Asinger RW, et al; American College of Cardiology/American Heart Association/European Society of Cardiology Board. ACC/AHA/ESC guidelines for the management of patients with atrial fibrillation: executive summary. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines and Policy Conferences (Committee to Develop Guidelines for the Management of Patients With Atrial Fibrillation): developed in collaboration with the North American Society of Pacing and Electrophysiology. J Am Coll Cardiol. 2001;38:1231-66. [PMID: 11583910] CrossrefMedlineGoogle Scholar2. Camm AJ, Lip GY, De Caterina, et al; ESC Committee for Practice Guidelines (CPG). 2012 focused update of the ESC Guidelines for the Management of Atrial Fibrillation: an update of the 2010 ESC Guidelines for the Management of Atrial Fibrillation. Developed with the special contribution of the European Heart Rhythm Association. Eur Heart J. 2012;33:2719-47. [PMID: 22922413] doi:10.1093/eurheartj/ehs253 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Perelman School of Medicine and Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PennsylvaniaUniversity of Michigan, Ann Arbor, MichiganPerelman School of Medicine, University of Pennsylvania, Philadelphia, PennsylvaniaDisclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M20-6194. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoEffectiveness and Safety of Direct Oral Anticoagulants Versus Warfarin in Patients With Valvular Atrial Fibrillation Ghadeer K. Dawwas , Eric Dietrich , Adam Cuker , Geoffrey D. Barnes , Charles E. Leonard , and James D. Lewis Effectiveness and Safety of Direct Oral Anticoagulants Versus Warfarin in Patients With Valvular Atrial Fibrillation Ishak A. Mansi , Sujata Bhushan , and David E. Albracht Effectiveness and Safety of Direct Oral Anticoagulants Versus Warfarin in Patients With Valvular Atrial Fibrillation Benjamin A. Rodwin Metrics October 2021Volume 174, Issue 10Page: 1490 ePublished: 19 October 2021 Issue Published: October 2021 Copyright & PermissionsCopyright © 2021 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...