tbuckley/cabot-search huggingface dataset:
Protracted Outbreaks of Cryptosporidiosis Associated With Swimming Pool Use—Ohio and Nebraska, 2000
Journal: JAMA (2001)

Swimming is the second most popular exercise in the United States with approximately 400 million pool visits annually. During the summer of 2000, five outbreaks of cryptosporidiosis linked to swimming pools were reported to CDC. This report summarizes the investigations of two of these outbreaks involving approximately 1000 cases and provides recommendations to reduce the transmission of pool-related disease.
Correction
Authors: F Parente, M Lazzaroni, G Bianchi Porro
Journal: Gut (1993)

used) increases the rate of healing.4On the other hand, the effectiveness of longterm maintenance treatment with sucralfate in healed refractory duodenal ulcer has still to be reported.Finally, we are in agreement with Moran et al that eradication regimens for H pylori infection should be considered not only for treatment of refractory duodenal ulcers, but also for symp- tomatic erosive duodenitis, especially if they proved to be resistant to conventional anti- secretive treatment.
Plasma soluble thrombomodulin levels are associated with mortality in the acute respiratory distress syndrome
Authors: Anil Sapru, Carolyn S. Calfee, Kathleen D. Liu, Kirsten Kangelaris, Helen Hansen, Ludmila Pawlikowska, Lorraine B. Ware, Mustafa F. Alkhouli, Jason Abbot, Michael A. Matthay
Journal: Intensive Care Medicine (2015)
Drug toxicity.
Authors: H A Bird
Journal: Annals of the Rheumatic Diseases (1990)

Drug toxicity H A BirdCost-benefit equation No drug is without side effects, so the decision to prescribe one implies a calculated gamble on the part of the doctor or the patient, or both, that the benefits of treatment will outweigh the disadvantages.This review does not attempt to assess the benefit but concentrates on the risk side of the equation.The concept of therapeutic risk is well recognised but is harder to define.' 2 The circumstances and expectations of each patient vary.Attempts have been made to explain relative risks by comparison with better under- stood concepts, such as the risk of lightning strike or road accident.3The risk of death may be the easiest of all to comprehend but fails to take into account most side effects which are trivial, though can still add to the misery of disease.The associated financial and social costs, perhaps of regular monitoring by blood tests, also require consideration.In 1974 Girdwood suggested that gold salts were signifi- cantly more toxic than any other treatment available in the United Kingdom.4When Rainsford catalogued the reports per year of deaths per million prescriptions5 antirheumatic drugs in the top 26 offenders included oxy- phenbutazone, acetylsalicycic acid, phenyl- butazone, and indomethacin.These figures date from before the widespread introduction of other non-steroidal anti-inflammatory drugs (NSAIDs) such as propionic acids.
Biologically active quinoline and quinazoline alkaloids part II
Authors: Xiao‐Fei Shang, Susan L. Morris‐Natschke, Guan‐Zhou Yang, Ying‐Qian Liu, Xiao Guo, Xiao‐Shan Xu, Masuo Goto, Jun‐Cai Li, Ji‐Yu Zhang, Kuo‐Hsiung Lee
Journal: Medicinal Research Reviews (2018)

To follow-up on our prior Part I review, this Part II review summarizes and provides updated literature on novel quinoline and quinazoline alkaloids isolated during the period of 2009-2016, together with the biological activity and the mechanisms of action of these classes of natural products. Over 200 molecules with a broad range of biological activities, including antitumor, antiparasitic and insecticidal, antibacterial and antifungal, cardioprotective, antiviral, anti-inflammatory, hepatoprotective, antioxidant, anti-asthma, antitussive, and other activities, are discussed. This survey should provide new clues or possibilities for the discovery of new and better drugs from the original naturally occurring quinoline and quinazoline alkaloids.
Blood Clots in People with the Factor V Leiden Mutation
Journal: Annals of Internal Medicine (2001)

Summaries for Patients4 September 2001Blood Clots in People with the Factor V Leiden MutationSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-135-5-200109040-00004 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail What is the problem and what is known about it so far?Blood clots occur commonly in deep veins in the legs. Pieces of these clots, known as emboli, can break off and travel through the bloodstream, blocking arteries in the lungs. These blood clots and emboli can cause serious symptoms and death. Surgery, pregnancy, trauma, hormone therapy, and inherited blood disorders increase risks for blood clots and emboli. Factor V Leiden is one of these inherited disorders. Although factor V Leiden is a common genetic defect, the actual incidence of clots and emboli among people with the defect is ... Author, Article, and Disclosure InformationAffiliations: The summary below is from the full report titled “A Prospective Study of Asymptomatic Carriers of the Factor V Leiden Mutation To Determine the Incidence of Venous Thromboembolism.” It is in the 4 September 2001 issue of Annals of Internal Medicine (volume 135, pages 322-327). The authors are S Middeldorp, JR Meinardi, MMW Koopman, ECM van Pampus, K Hamulyák, J van der Meer, MH Prins, and HR Büller.Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. The summaries may be reproduced for not-for-profit educational purposes only. Any other uses must be approved by the American College of Physicians-American Society of Internal Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoA Prospective Study of Asymptomatic Carriers of the Factor V Leiden Mutation To Determine the Incidence of Venous Thromboembolism Saskia Middeldorp , Johan R. Meinardi , Maria M.W. Koopman , Elisabeth C.M. van Pampus , Karly Hamulyák , Jan van der Meer , Martin H. Prins , and Harry R. Büller Metrics 4 September 2001Volume 135, Issue 5Page: I-34KeywordsFactor V LeidenFemale contraceptionHormonesLungsPregnancySurgeryThrombosisTrauma surgeryVeinsVenous thromboembolism ePublished: 4 September 2001 Issue Published: 4 September 2001 Copyright & PermissionsCopyright © 2001 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Pericarditis in Juvenile Rheumatoid Arthritis
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Faux amis
Authors: Jeff Aronson
Journal: BMJ (2005)

exclude a clinically significant benefit of supplementation owing to the relatively wide confidence intervals around our estimate of effect.We thank Nicky Cullum, Bill Gillespie, and Jill Mollison for acting as the independent trial steering group and data monitoring committee; Sue New for scoring the calcium questionnaire; and Corrina Petre for helping with randomisation.
Studies of Venereal Disease
Authors: King K. Holmes
Journal: JAMA (1967)

Postgonococcal urethritis (PGU) occurred in nearly two thirds of men with gonorrhea acquired in the Far East who were "successfully" treated with 2,400,000 units of procaine penicillin G plus probenecid. PGU occurred less often after treatment of gonorrhea with tetracycline hydrochloride, and PGU itself responded to tetracycline, suggesting a microbial etiology for the condition. The syndrome was associated to a highly significant degree with<i>Mycoplasma</i>infection of the urethra, and occurred more often after infection with Neisseria<i>gonorrhoeae</i>of lessened penicillin sensitivity. The high incidence of the syndrome, one of the most common infectious diseases among military personnel in the Far East, requires a reexamination of the traditional use of penicillin in the treatment of gonorrhea in men.
Canadian Journal of Surgery, Toronto
Journal: JAMA (1962)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Interhospital transfer of acutely ill cardiac patients
Authors: R. O. Cummins
Journal: JAMA (1988)

Complex issues arise whenever the topic of patient transfer is examined. These include the clinical indications for transfer,<sup>1,2</sup>whether the transfer produced adverse clinical effects,<sup>3</sup>and patient stabilization before transfer.<sup>4</sup>There are also questions about the professional level of the transfer personnel<sup>5</sup>and, in this era of burgeoning aeromedical services, about the best mode of transport.<sup>6</sup>In addition, the subject evokes concern over preferential transfer of financially undesirable patients<sup>7-10</sup>and the regionalization of health care resources.<sup>11,12</sup> See also p 1695. In this issue ofTHE JOURNAL, Rubenstein et al<sup>13</sup>present a descriptive study that is useful, even though it sidesteps some of these issues. The article describes 755 acutely ill cardiac patients who were successfully transferred from any of seven Kaiser Permanente medical facilities to a tertiary medical center in Los Angeles. A large majority (96%) of the patients were accompanied only
A Treatise on Diseases of the Anus, Rectum and Pelvic Colon.
Journal: JAMA (1903)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Unreviewed Reports
Authors: D Machin, R Crosbie
Journal: BMJ (1986)

Hepatic mesenchymoma in an adultA 21 year old woman presented with abdominal pain and a mass in the right upper quadrant.At laparotomy a huge tumour (2-25 kg) was found arising from and largely replacing the left lobe of the liver.Left hepatic lobectomy was carried out.Histological examination showed a malignant mesenchymoma-a tumour that is exceedingly rare outside childhood.Oral contraceptives have been incriminated in the aetiology of hepatic tumours.'This patient had been taking the pill (Norinyl-l) for 66 months, and this may have been a relevant factor in the development of her hepatic mesenchymoma.-
Reversal of RNA toxicity in myotonic dystrophy via a decoy RNA-binding protein with high affinity for expanded CUG repeats
Authors: Ludovic Arandel, Magdalena Matloka, Arnaud F. Klein, Frédérique Rau, Alain Sureau, Michel Ney, Aurélien Cordier, Maria Kondili, Micaela Polay-Espinoza, Naira Naouar, Arnaud Ferry, Mégane Lemaitre, Séverine Begard, Morvane Colin, Chloé Lamarre, Hélène Tran, Luc Buée, Joëlle Marie, Nicolas Sergeant, Denis Furling
Journal: Nature Biomedical Engineering (2022)
Low-dose oral corticosteroids in asthma associates with increased morbidity and mortality
Authors: Inge Raadal Skov, Hanne Madsen, Daniel Pilsgaard Henriksen, Jacob Harbo Andersen, Anton Pottegård, Jesper Rømhild Davidsen
Journal: European Respiratory Journal (2022)

Long-term oral corticosteroid (OCS) treatment for severe asthma is known to cause significant adverse effects, but knowledge on effects of lower exposures in general asthma populations is limited. We aimed to explore this in a nationwide Danish asthma population.Users of asthma medication aged 18-45 years were identified in the Danish nationwide registers during 1999-2018 and followed prospectively in an open-cohort design. Incident OCS users were matched 1:4 to nonusers by propensity scores with replacement. Associations between OCS use and incident comorbidities were examined by Cox regression. Mortality rates, causes of death and rates of unscheduled hospital visits were assessed.OCS users (n=30 352) had, compared with nonusers (n=121 408), an increased risk of all outcomes with evident dose-response relationships starting at cumulative doses of ≤500 mg (prednisolone-equivalent). Hazard ratios ranged from 1.24 (95% CI 1.18-1.30) for fractures to 8.53 (95% CI 3.97-18.33) for adrenal insufficiency. Depression/anxiety had the highest incidence rate difference at 4.3 (95% CI 3.6-5.0) per 1000 person-years. Asthma-specific mortality rates were generally low at 0.15 (95% CI 0.11-0.20) and 0.04 (95% CI 0.02-0.06) per 1000 person-years for OCS users and nonusers, respectively. Mortality rates and unscheduled hospital visits increased with increasing OCS exposure.The study findings should be interpreted with their observational nature in mind. However, we found that even at low cumulative exposure, OCS use in asthma management was associated with increased risk of comorbidities, mortality and unscheduled hospital visits. Effective strategies for optimising asthma control and reducing OCS use are pivotal in asthma management.
From the Congressional Office of Technology Assessment
Authors: E. J. Power
Journal: JAMA (1995)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Books Received
Journal: JAMA (1985)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Society Proceedings
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Tetany
Journal: Annals of Internal Medicine (1930)

Article1 November 1930TetanyJONATHAN MEAKINSJONATHAN MEAKINSSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-4-5-462 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTetany has been recognized as a clinical entity since the classical description by Clarke in 1815. It appears with great frequency in the older literature but has become of progressively less importance as a distinct symptom complex during the past thirty years. It has been reported in epidemic form in both Europe and America; when it appeared to have a seasonal occurrence particularly in March and April and affected young men between the ages of sixteen and twenty-five, seldom appearing in women.Like many syndromes of the past, the etiology of which was not understood, it was classified as a...Bibliography1 MACCALLUMVOEGTLIN : Journ. Exper. Med., 1909, XI, 118. CrossrefGoogle Scholar2 BLUMGART HL: Arch. Internal Med, 1923, XXXII, 113. CrossrefGoogle Scholar3 HOLMESSTARR : Journ. Amer. Med. Assoc., 1929, XCII, 975. CrossrefGoogle Scholar4 SALVESENLINDER : Jour. Biol. Chem., 1923, LVIII, 617. CrossrefGoogle Scholar5 PETERSEISERSON : Journ. Biol. Chem., 1929, LXXXIV, 161. Google Scholar6 DALEEVANS : Journ. Physiol., 1922, LVI, 125. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Montreal Canada*Presented before the American College of Physicians, Minneapolis, Minn., February 13, 1930. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 November 1930Volume 4, Issue 5Page: 462-466KeywordsEtiology ePublished: 1 December 2008 Issue Published: 1 November 1930 PDF downloadLoading ...
The Future of the Disabled Soldier.
Journal: JAMA (1918)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Case 4-2022: A 55-Year-Old Man with Bilateral Hearing Loss and Eye Redness
Authors: Jeffrey P. Harris, Andrea L. Ciaranello, Elisabeth S. Tabb
Journal: New England Journal of Medicine (2022)

A 55-year-old man was evaluated in the rheumatology clinic because of bilateral hearing loss and eye redness. He had had fatigue and intermittent body aches for 2 months and had lost 5 kg of weight over a 6-month period. There was redness in both eyes and grossly reduced hearing in both ears. A diagnostic test was performed.