BIOLOGIC FALSE POSITIVE SEROLOGIC TESTS FOR SYPHILIS
Authors: C. F. M.
Journal: Annals of Internal Medicine (1940)

Editorial1 July 1940BIOLOGIC FALSE POSITIVE SEROLOGIC TESTS FOR SYPHILISC. F. M.C. F. M.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-14-1-171 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSince the introduction of the Wassermann test in 1906, opinion as to the specificity of serologic tests for syphilis, if reports in the literature reflect the general impressions of the times, has passed through three distinct phases. From 1906 to 1918, many organic diseases, as well as pregnancy, menstruation, and the effect of various drugs, were reported to cause false positive Wassermann tests. In the period 1918 to 1928, these false positive tests were thought to be due to faulty technic or the associated presence of symptomless syphilis, and serologic tests for syphilis were regarded as amazingly specific.From 1928...1 KEMPFITZGERALDSHEPHERD JEEMM: The occurrence of positive serologic tests for syphilis in animals other than man, with a review of the literature, Am. Jr. Syph., Gonor. and Ven. Dis. (In Press.) Google Scholar2 DREYERWALKER GEW: Neues zur Theorie der Wassermannschen Reaktion, Biochem. Ztschr., 1913, liv, 11. Google Scholar3 BROWNING CN: Biochemistry of immune reactions, Brit. Med. Jr., 1915, i, 239. CrossrefGoogle Scholar4 MEINICKE E: Theorie und Methodik der serologischen Luesdiagnostik, Deutsch. med. Wchnschr., 1919, xiv, 178. CrossrefGoogle Scholar5 VERNES A: Sur la précipitation d'un colloöde organique par le serum human normal ou syphilitique, Compt. rend. Acad. d. sci., 1918, clxvi, 575. Google Scholar6 MALLOYKAHN AMRL: The ultramicroscopic precipitation reaction in syphilis, Jr. Infect Dis., 1931, xlviii, 243. CrossrefGoogle Scholar7 BARNETTJONESKULCHAR CWRBGV: Measurement of reagin in non-syphilitic sera, Proc. Soc. Exper. Biol. and Med., 1935, xxxiii, 214. CrossrefGoogle Scholar8 EAGLE H: On the specificity of serologic tests for syphilis, as determined by 40, 545 tests in a college student population. (In Press.) Google Scholar9 ESTER F: Sul comportamento di alcune sieroreazioni della sifilide sul siero di sangue dei non luetici inoculati sperimentalmente con malaria terzana benigna, Gior. di batteriol. e immunol., 1936, xvii, 502. Google Scholar10 KITCHENWEBBKUPPER SFELWH: The influence of malarial infection on the Wassermann and Kahn reactions, Jr. Am. Med. Assoc., 1939, cxii, 1443. CrossrefGoogle Scholar11 MOORE JE: A suggested method of approach to the recognition of the biologic false positive serologic test for syphilis, Bull. Genitoinfect. Dis., 1940, iii, 1. Google Scholar12 KAHN RL: A serologic verification test in the diagnosis of latent syphilis, Arch. Dermat. and Syph., 1940, xii, 817. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 July 1940Volume 14, Issue 1Page: 171-173KeywordsBiologicsDrugsPregnancySpecificitySyphilis ePublished: 1 December 2008 Issue Published: 1 July 1940 PDF downloadLoading ...