tbuckley/cabot-search huggingface dataset:
Hussey Quits Board to Head AMA Division of Scientific Activities
Journal: JAMA (1962)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Ingenious Pain
Authors: Tony Miksanek
Journal: JAMA (1997)

Imagine a man untouched by pain. Consider the possibility of an individual who until his late twenties has never experienced suffering. No, this is an episode of "The X-Files" or a comic book character but rather the premise of a splendid novel,<i>Ingenious Pain</i>. It is a book so unique and powerful that it dares to begin with the autopsy of its main character. Dr James Dyer is an 18th-century English physician who is both a prodigy and enigma. He is an illegitimate child who enters the world without crying at birth and discovers he is insensitive to pain. He cannot be hurt. Unlike the rest of us, even life is unable to teach the young Dyer how to suffer. In an age devoid of miracles and characterized by limited medical skills, Dyer becomes a remarkable surgeon though only in his early twenties. Dyer is an efficient cutting machine, a
Highly Stretchable, Adhesive, and Self‐Healing Silk Fibroin‐Dopted Hydrogels for Wearable Sensors
Authors: Li Zhao, Jizhong Zhao, Fan Zhang, Zijie Xu, Fan Chen, Yating Shi, Chen Hou, Yicheng Huang, Changjian Lin, Rui Yu, Wenxi Guo
Journal: Advanced Healthcare Materials (2021)

Adv. Healthcare Mater. 2021, 10, 2002083 DOI: 10.1002/adhm.202002083 In the published version of this article, the word "doped" in misspelled as "dopted" throughout the article. This mistake appears in the Title, the Abstract, the Introduction, and Conclusion. The correct title is: Highly Stretchable, Adhesive, and Self-Healing Silk Fibroin-Doped Hydrogels for Wearable Sensors The correct sentence in the Abstract is: Here, a simple one-pot method of thermal polymerization is introduced to fabricate silk fibroin-doped hydrogels (SFHs), which are both chemically and physically cross-linked by acrylamide (AM), acrylic acid (AA), and silk fibroin (SF). The correct sentence in the Introduction is: The addition of SF solution can improve the water retention property of silk fibroin-doped hydrogels (SFHs),[42] and effectively increases the mechanical properties. The correct sentence in the Conclusion is: In summary, we have prepared a chemical and physical cross-linked network hydrogel doped by SF with one-pot method of thermal polymerization. The editorial office apologizes for this oversight and for any confusion caused.
THE RESECTION OF THE SYMPATHETIC.
Journal: JAMA (1898)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Count on us: T cells in SARS-CoV-2 infection and vaccination
Authors: Katherine Kedzierska, Paul G. Thomas
Journal: Cell Reports Medicine (2022)

Robust T cell responses have been associated with milder outcomes in many infections. T cells also establish long-term memory pools and, as they are predominantly directed toward epitopes encompassing conserved peptides, can respond to SARS-CoV-2 variants, including Omicron. Here, we discuss epitope-specific CD8
Comparison between adalimumab introduction and methotrexate dose escalation in patients with inadequately controlled psoriatic arthritis (CONTROL): a randomised, open-label, two-part, phase 4 study
Authors: Laura C Coates, William Tillett, Maria-Antonietta D'Agostino, Proton Rahman, Frank Behrens, Erin L McDearmon-Blondell, Xianwei Bu, Liang Chen, Mudra Kapoor, Philip G Conaghan, Philip Mease
Journal: The Lancet Rheumatology (2022)

Many patients with psoriatic arthritis do not reach minimal disease activity (MDA) on methotrexate alone. This phase 4 open-label study aimed to compare attainment of MDA following introduction of adalimumab with methotrexate escalation in patients with psoriatic arthritis who do not reach MDA after an initial methotrexate course (≤15 mg every week).
Confinia Neurologica, Basel
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A Correction to the Research Article Titled: “Inhibition of Transplantation Tolerance by Immune Senescence Is Reversed by Endocrine Modulation” by G. Zhao, D. J. Moore, J. I. Kim, K. M. Lee, M. R. O’Connor, P. E. Duff, M. Yang, J. Lei, J. F. Markmann, S. Deng
Journal: Science Translational Medicine (2011)
Adoptive transfer of ex vivo expanded regulatory T cells improves immune cell engraftment and therapy-refractory chronic GvHD
Authors: Sybille Landwehr-Kenzel, Leonie Müller-Jensen, Joern-Sven Kuehl, Mohamed Abou-el-Enein, Henrike Hoffmann, Sandra Muench, Daniel Kaiser, Andy Roemhild, Horst von Bernuth, Mirjam Voeller, Michael Schmueck-Henneresse, Bernd Gruhn, Ulrik Stervbo, Nina Babel, Hans-Dieter Volk, Petra Reinke
Journal: Molecular Therapy (2022)

Graft-versus-host disease (GvHD) is still the major non-relapse, life-limiting complication after hematopoietic stem cell transplantation. Modern pharmacologic immunosuppression is often insufficient and associated with significant side effects. Novel treatment strategies now include adoptive transfer of <i>ex vivo</i> expanded regulatory T cells (Tregs), but their efficacy in chronic GvHD is unknown. We treated three children suffering from severe, therapy-refractory GvHD with polyclonally expanded Tregs generated from the original stem cell donor. Third-line maintenance immunosuppression was tapered to cyclosporin A and low-dose steroids shortly before cell transfer. Regular follow-up included an assessment of the subjective and objective clinical development, safety parameters, and in-depth immune monitoring. All patients showed marked clinical improvement with substantially decreased GvHD activity. Laboratory follow-up showed a significant enhancement of the immunologic engraftment, including lymphocytes and dendritic cells. Monitoring the fate of Tregs by next-generation sequencing demonstrated clonal expansion. In summary, adoptive transfer of Tregs was well tolerated and able to modulate an established undesired T cell mediated allo-response. Although no signs of overimmunosuppression were detectable, the treatment of patients with invasive opportunistic infections should be undertaken with caution. Further controlled studies are necessary to confirm these encouraging effects and eventually pave the way for adoptive Treg therapy in chronic GvHD.
Reliever-Triggered Inhaled Glucocorticoid in Black and Latinx Adults with Asthma
Authors: Elliot Israel, Juan-Carlos Cardet, Jennifer K. Carroll, Anne L. Fuhlbrigge, Lilin She, Frank W. Rockhold, Nancy E. Maher, Maureen Fagan, Victoria E. Forth, Barbara P. Yawn, Paulina Arias Hernandez, Jean M. Kruse, Brian K. Manning, Jacqueline Rodriguez-Louis, Joel B. Shields, Brianna Ericson, Alex D. Colon-Moya, Suzanne Madison, Tamera Coyne-Beasley, Gretchen M. Hammer, Barbara M. Kaplan, Cynthia S. Rand, Janet Robles, Opal Thompson, Michael E. Wechsler, Juan P. Wisnivesky, M. Diane McKee, Sunit P. Jariwala, Elina Jerschow, Paula J. Busse, David C. Kaelber, Sylvette Nazario, Michelle L. Hernandez, Andrea J. Apter, Ku-Lang Chang, Victor Pinto-Plata, Paul M. Stranges, Laura P. Hurley, Jennifer Trevor, Thomas B. Casale, Geoffrey Chupp, Isaretta L. Riley, Kartik Shenoy, Magdalena Pasarica, Rafael A. Calderon-Candelario, Hazel Tapp, Ahmet Baydur, Wilson D. Pace
Journal: New England Journal of Medicine (2022)

Black and Latinx patients bear a disproportionate burden of asthma. Efforts to reduce the disproportionate morbidity have been mostly unsuccessful, and guideline recommendations have not been based on studies in these populations.
Biallelic pathogenic variants in roundabout guidance receptor 1 associate with syndromic congenital anomalies of the kidney and urinary tract
Authors: Johannes Münch, Marie Engesser, Ria Schönauer, J. Austin Hamm, Christin Hartig, Elena Hantmann, Gulsen Akay, Davut Pehlivan, Tadahiro Mitani, Zeynep Coban Akdemir, Beyhan Tüysüz, Toshihiko Shirakawa, Sumito Dateki, Laura R. Claus, Albertien M. van Eerde, Thomas Smol, Louise Devisme, Hélène Franquet, Tania Attié-Bitach, Timo Wagner, Carsten Bergmann, Anne Kathrin Höhn, Shirlee Shril, Ari Pollack, Tara Wenger, Abbey A. Scott, Sarah Paolucci, Jillian Buchan, George C. Gabriel, Jennifer E. Posey, James R. Lupski, Florence Petit, Andrew A. McCarthy, Gregory J. Pazour, Cecilia W. Lo, Bernt Popp, Jan Halbritter
Journal: Kidney International (2022)
Oral N-acetylcysteine and exacerbation rates in patients with chronic bronchitis and severe airways obstruction. British Thoracic Society Research Committee.
Authors: J Macfarlane
Journal: Thorax (1985)

The influence of oral N-acetylcysteine on the exacerbation rate in patients with chronic bronchitis and severe airways obstruction has been studied. Two hundred and forty four patients entered the study during October and November 1983 and took placebo sachets for a run in month. One hundred and eighty one who completed this month satisfactorily were randomised to receive either active (acetylcysteine 200 mg three times a day) or matching placebo sachets for five months in a double blind parallel group study. The two groups were well matched. Patients kept detailed daily symptom diaries and were assessed monthly. At the end of the five months' study the outcome in the group taking acetylcysteine appeared a little better, but the differences did not reach conventional levels of statistical significance for the mean (SD) number of exacerbations (2.1 (0.2) for acetylcysteine, 2.6 (0.2) for placebo; p = 0.08); total days taking an antibiotic (13.5 (1.7), 18.0 (2.8); p = 0.17); total days spent in bed (4.8 (0.8), 5.1 (1.1); p = 0.9); number of withdrawals (13 (15%), 20 (21%); p = 0.4); incidence of side effects (which were few); drug compliance (which was good); and the patients' assessment of the treatment.
Correction: Increased Risk of Colon Cancer Associated with a Genetic Polymorphism of <i>SMAD7</i>
Journal: Cancer Research (2010)

In this article (Cancer Res 2010;70:1479–85), which was published in the February 15, 2010 issue of Cancer Research (1), the layout of Table 3 is incorrect; the correct table appears below. Also, the correct header of the fourth column in Table 4 is “CIMP low OR (95% CI)” and the correct header of the fifth column is “Cases n”.
THE DEAN OF A MEDICAL COLLEGE— A JOB ANALYSIS
Journal: JAMA (1949)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Schizophrenia
Authors: Cara M. Borelli, Hugo Solari
Journal: JAMA (2019)

SchizophreniaSchizophrenia is a psychiatric disorder that affects approximately 1% of people worldwide.People with schizophrenia often have hallucinations, which are false perceptions that occur when a stimulus is not actually present.Types of hallucinations include auditory, visual, and tactile hallucinations.Auditory hallucinations are the most common and may be experienced as hearing people talking.Auditory hallucinations can be stressful to the person experiencing them.For example, the voices may cause difficulty with concentration, they may insult the person experiencing them, or they may tell the person to do something that the person does not want to do.Delusions are another common symptom of schizophrenia.Delusions are false beliefs that are held even though there is evidence that they are not true.Like hallucinations, delusions have the potential to be quite distressing to the person experiencing them.One type of delusion is a paranoid delusion, in which a person believes that they are being persecuted.For example, the person may believe that someone is attempting to stalk or poison them.Other symptoms of schizophrenia include disorganized speech, poor hygiene, decreased motivation, difficulty expressing emotions, and decreased interest in socializing with friends and family.Cognitive symptoms, such as those that interfere with working memory, frequently cause disability.People with schizophrenia can experience symptoms of mania, depression, or anxiety.Additionally, people with schizophrenia may have problems with using illicit drugs, alcohol, and cigarettes.Symptoms associated with other psychiatric disorders as well as use of illicit substances tend to worsen schizophrenia.
Primary and Secondary Syphilis—United States, 2000-2001
Journal: JAMA (2002)

After declining every year during 1990-2000, the rate of primary and secondary (P&S) syphilis in the United States increased in 2001. To characterize the epidemiology of syphilis in the United States, CDC analyzed national surveillance data for 2002. This report summarizes the results of that analysis, which indicate that the number of reported cases of P&S syphilis increased 12.4% in 2002. As in 2001, this increase occurred only among men, suggesting that this increase occurred particularly among men who have sex with men (MSM). For the 12th consecutive year, the number of P&S syphilis cases declined among women and non-Hispanic blacks. These data suggest that although efforts to reduce syphilis among these populations have been effective, additional intervention strategies are needed to prevent syphilis among MSM.
DIABETES FROM INJECTION OF ADRENALIN.
Journal: JAMA (1902)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Postgraduate Haematology
Authors: Mehdi Tavassoli
Journal: JAMA (1989)

This is the third edition of this quasitextbook of which the first edition appeared in 1972. The present edition was necessitated, not so much because of the market demand, but probably because since the first edition the perspective of hematology has changed completely, in its science as well as practice. This change has come about as a result of applications of molecular biologic and immunologic techniques. The landscape would no longer be recognizable to those of us who were trained before this era, were we not ourselves in the midst of the changing pattern or were it not because of a book like this. The book has indeed incorporated much of the recent developments and, to the delight of its readers, a large portion is in the form of encapsulated, easily digestible tabulation and diagrams. The sections on lymphoproliferative and myeloproliferative disorders, the areas that are most responsible for the
DP11: Preferentially expressed antigen in melanoma (PRAME): the holy grail in melanocytic pathology?
Journal: British Journal of Dermatology (2021)

inflammatory arthritis and rapidly progressive ILD, which is frequently fatal.Although our patient had ILD, she was relatively stable on minimal immunosuppression.It is important for clinicians to have an increased awareness of this disease as it could have a highly variable clinical presentation in the white population.
LETTER FROM NEW YORK.
Authors: None P. B. P.
Journal: JAMA (1889)

(FROM OUR OWN CORRESPONDENT.) Simple, Non-tubercular, Non-metastatic Abscess of the Lungs—Pigmentation of the Body by Arsenic. At the last meeting of the Section on Practice of the New York Academy of Medicine, Dr. S. Seabury Jones read a paper on<i>Simple, Non-tubercular, Non-metastatic Abscess of the Lungs</i>. This was a subject, he said, which had received but little attention. The affection, however, was comparatively rare, and Trousseau in the first twenty-five years of his hospital practice did not meet with a single case, though he afterwards reported two cases. Laennec met with only five cases in several hundred autopsies on those who had died of pneumonia. In 1848 Robert Graves reported six cases. When Dr. Jones encountered his first case, now nine years ago, he was unable to find any reference to the subject whatever in any of the text-books to which he had access. Later some attention was given
Engineering pre-vascularized bone-like tissue from human mesenchymal stem cells through simulating endochondral ossification
Authors: Zixuan Lin, Xiurui Zhang, Madalyn R. Fritch, Zhong Li, Biao Kuang, Peter G. Alexander, Tingjun Hao, Guorui Cao, Susheng Tan, Katherine K. Bruce, Hang Lin
Journal: Biomaterials (2022)
The response to cardiac resynchronization therapy in <scp>LMNA</scp> cardiomyopathy
Authors: Kiran Sidhu, Anna Isotta Castrini, Victoria Parikh, Nosheen Reza, Anjali Owens, Maxime Tremblay‐Gravel, Matthew T. Wheeler, Luisa Mestroni, Matthew Taylor, Sharon Graw, Marta Gigli, Marco Merlo, Alessia Paldino, Gianfranco Sinagra, Daniel P. Judge, Hannia Ramos, Olurotimi Mesubi, Emily Brown, Samual Turnbull, Saurabh Kumar, Darius Roy, Usha B. Tedrow, Long Ngo, Kristina Haugaa, Neal K. Lakdawala
Journal: European Journal of Heart Failure (2022)
The Mechanism Of Action Of Nerve Growth Factor
Authors: A Levi
Journal: The Annual Review of Pharmacology and Toxicology (1991)

Heme oxygenases (HO) catabolize free heme, that is, iron (Fe) protoporphyrin (IX), into equimolar amounts of Fe2+, carbon monoxide (CO), and biliverdin. The stress-responsive HO-1 isoenzyme affords protection against programmed cell death. The mechanism ...Read More
THE PROBLEM OF OXYGEN THERAPY
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal