tbuckley/cabot-search huggingface dataset:
The Road Not Taken
Authors: Joseph Gascho
Journal: JAMA Neurology (2022)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Neurology HomeNew OnlineCurrent IssueFor Authors Podcast Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Neurology journal
ARTIFICIAL INTELLIGENCE-AUGMENTED ECG IN DETERMINING SEX: CORRELATION WITH SEX HORMONE LEVELS
Authors: Jwan Naser, Abraham Baez Suarez, Zachi Itzhak Attia, Alice Y. Chang, Sorin Pislaru, Patricia A. Pellikka, Grace Lin, Suraj Kapa, Francisco Lopez-Jimenez, Paul A. Friedman, Peter Noseworthy
Journal: Journal of the American College of Cardiology (2022)
LONG-TERM EXERCISE OUTCOMES IN A CONTEMPORARY COHORT OF CHILDREN WITH CONGENITAL DIAPHRAGMATIC HERNIA AND PULMONARY HYPERTENSION.
Authors: Kimberley Miles, Adam William Powell, Paul Critser, Meredith Oneil, Elizabeth Geers, Michelle Cash, Wayne Mays, Stephanie Melissa Magness, Russel Hirsch
Journal: Journal of the American College of Cardiology (2022)
VENTRICULAR INVERSION WITH VENTRICULOARTERIAL CONCORDANCE: A COMPLEX CARDIOVASCULAR PHYSIOLOGY IN A NEWBORN WITH SITUS INVERSUS
Authors: Hector A. Oliveras Cordero, Rolando Encarnación, Luis Rivera-Martínez, Yazmin Ortiz-Sánchez, Ines García-García, Enrique Carrión-Vargas
Journal: Journal of the American College of Cardiology (2022)
TEMPORAL TRENDS OF HEART FAILURE COMPLICATING ATRIAL FIBRILLATION HOSPITALIZATIONS IN THE UNITED STATES
Authors: Shivaraj Patil, Chaitanya Rojulpote, Karthik Gonuguntla, Manish Kumar, Madhuwani Rojulpote, Aman M. Amanullah
Journal: Journal of the American College of Cardiology (2022)
FORECASTING TRENDS IN CARDIOMETABOLIC RISK FACTORS IN THE UNITED STATES: ESTIMATES BASED ON THE 2020 CENSUS
Authors: Reza Mohebi, Chen Chen, Cian P. McCarthy, Hanna Kim Gaggin, Daniel E. Singer, Emily Parker Hyle, Jason H. Wasfy, James L. Januzzi
Journal: Journal of the American College of Cardiology (2022)
Long-term hyperglycemia aggravates α-synuclein aggregation and dopaminergic neuronal loss in a Parkinson’s disease mouse model
Authors: Yi-Qing Lv, Lin Yuan, Yan Sun, Hao-Wen Dou, Ji-Hui Su, Zhi-Pan Hou, Jia-Yi Li, Wen Li
Journal: Translational Neurodegeneration (2022)

Growing evidence suggests an association between Parkinson's disease (PD) and diabetes mellitus (DM). At the cellular level, long-term elevated levels of glucose have been shown to lead to nigrostriatal degeneration in PD models. However, the underlying mechanism is still unclear. Previously, we have elucidated the potential of type 2 diabetes mellitus (T2DM) in facilitating PD progression, involving aggregation of both alpha-synuclein (α-syn) and islet amyloid polypeptide in the pancreatic and brain tissues. However, due to the complicated effect of insulin resistance on PD onset, the actual mechanism of hyperglycemia-induced dopaminergic degeneration remains unknown. We employed the type 1 diabetes mellitus (T1DM) model induced by streptozotocin (STZ) injection in a transgenic mouse line (BAC-α-syn-GFP) overexpressing human α-syn, to investigate the direct effect of elevated blood glucose on nigrostriatal degeneration. STZ treatment induced more severe pathological alterations in the pancreatic islets and T1DM symptoms in α-syn-overexpressing mice than in wild-type mice, at one month and three months after STZ injections. Behavioral tests evaluating motor performance confirmed the nigrostriatal degeneration. Furthermore, there was a marked decrease in dopaminergic profiles and an increase of α-syn accumulation and Serine 129 (S129) phosphorylation in STZ-treated α-syn mice compared with the vehicle-treated mice. In addition, more severe neuroinflammation was observed in the brains of the STZ-treated α-syn mice. Our results solidify the potential link between DM and PD, providing insights into how hyperglycemia induces nigrostriatal degeneration and contributes to pathogenic mechanisms in PD.
ACUTE RIGHT VENTRICULAR FAILURE AND CARDIOGENIC SHOCK SECONDARY TO RIGHT CORONARY OCCLUSION AFTER SURGICAL AORTIC VALVE REPLACEMENT
Authors: Joe Aoun, Syed Zaid, Bharat Narasimhan, Hassaan Arshad, Qasim Al Abri, Michael J. Reardon, Sachin S. Goel
Journal: Journal of the American College of Cardiology (2022)
PROGNOSTIC VALUE OF ECHOCARDIOGRAPHIC ASSESSMENT OF LEFT VENTRICULAR FUNCTION IN PATIENTS WITH COVID-19 COMPLICATED BY SHOCK
Authors: Brent Klinkhammer, Matthew J. Fata, Steven M. Hollenberg, Lucy M. Safi, David B. Landers, Zoltan Turi, Tirth Talati, Osman K. Yousafzai, Taya V. Glotzer, Jana Tancredi, Joseph E. Parrillo
Journal: Journal of the American College of Cardiology (2022)
THE PROGNOSTIC RELATION OF INVASIVE MICROVASCULAR FUNCTION INDICES AND THEIR EVOLVEMENT WITH 1-MONTH FUNCTIONAL OUTCOME AFTER REPERFUSED ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION
Authors: Ahmet Demirkiran, Lourens FHJ Robbers, Nina Willemijn van der Hoeven, Henk Everaars, Luuk Hopman, Gladys Janssens, Jorrit Lemkes, Arno A. van de Bovenkamp, Maarten Van Leeuwen, Alexander Nap, Ramon Van Loon, Guus de Waard, Albert van Rossum, Niels Van Royen, Robin Nijveldt
Journal: Journal of the American College of Cardiology (2022)
PULMONARY HYPERTENSION AS A PREDICTOR FOR INCREASED MORTALITY IN PATIENTS UNDERGOING PERCUTANEOUS LEFT ATRIAL APPENDAGE OCCLUDER DEVICE PLACEMENT
Authors: Hiren R. Patel, Sundeep Kumar, Ruthvik Srinivasamurthy, Ali Ghani, Sarika Kumari, Ziad SayedAhmad, Zachary Oman, Mohsin Mughal, Akhil Mogalapalli, Sayed Tahir Hussain, Philip L. Mar, Ammar Nasir, Kishore J. Harjai
Journal: Journal of the American College of Cardiology (2022)
Persistent B cell memory after SARS-CoV-2 vaccination is functional during breakthrough infections
Authors: Sara Terreri, Eva Piano Mortari, Maria Rosaria Vinci, Cristina Russo, Claudia Alteri, Christian Albano, Francesca Colavita, Giulia Gramigna, Chiara Agrati, Giulia Linardos, Luana Coltella, Luna Colagrossi, Gloria Deriu, Marta Ciofi Degli Atti, Caterina Rizzo, Marco Scarsella, Rita Brugaletta, Vincenzo Camisa, Annapaola Santoro, Giuseppe Roscilli, Emiliano Pavoni, Alessia Muzi, Nicola Magnavita, Rossana Scutari, Alberto Villani, Massimiliano Raponi, Franco Locatelli, Carlo Federico Perno, Salvatore Zaffina, Rita Carsetti
Journal: Cell Host & Microbe (2022)

Breakthrough SARS-CoV-2 infections in fully vaccinated individuals are considered a consequence of waning immunity. Serum antibodies represent the most measurable outcome of vaccine-induced B cell memory. When antibodies decline, memory B cells are expected to persist and perform their function, preventing clinical disease. We investigated whether BNT162b2 mRNA vaccine induces durable and functional B cell memory in vivo against SARS-CoV-2 3, 6, and 9 months after the second dose in a cohort of health care workers (HCWs). While we observed physiological decline of SARS-CoV-2-specific antibodies, memory B cells persist and increase until 9 months after immunization. HCWs with breakthrough infections had no signs of waning immunity. In 3-4 days, memory B cells responded to SARS-CoV-2 infection by producing high levels of specific antibodies in the serum and anti-Spike IgA in the saliva. Antibodies to the viral nucleoprotein were produced with the slow kinetics typical of the response to a novel antigen.
VENTRICULAR SEPTAL DEFECT (VSD) DUE TO LATE PRESENTING RIGHT CORONARY ARTERY INFARCTION WITH DEHISCIENCE OF PERCUTANEOUS SEPTAL OCCLUDER REQUIRING EMERGENT ECMO AS A BRIDGE TO SURGICAL VSD CLOSURE
Authors: Ethan Fry, Naoki Misumida, Hassan K. Reda
Journal: Journal of the American College of Cardiology (2022)
Autologous treatment for ALS with implication for broad neuroprotection
Authors: Daehwan Kim, Subin Kim, Ashley Sung, Neetika Patel, Nathan Wong, Michael J. Conboy, Irina M. Conboy
Journal: Translational Neurodegeneration (2022)

Abstract Background Amyotrophic lateral sclerosis (ALS) is characterized by a progressive loss of motor neurons (MNs), leading to paralysis, respiratory failure and death within 2–5 years of diagnosis. The exact mechanisms of sporadic ALS, which comprises 90% of all cases, remain unknown. In familial ALS, mutations in superoxide dismutase (SOD1) cause 10% of cases. Methods ALS patient-derived human-induced pluripotent stem cells (ALS hiPSCs, harboring the SOD1 AV4 mutation), were differentiated to MNs (ALS-MNs). The neuroprotective effects of conditioned medium (CM) of hESCs (H9), wt hiPSCs (WTC-11) and the ALS iPSCs, on MN apoptosis and viability, formation and maintenance of neurites, mitochondrial activity and expression of inflammatory genes, were examined. For in vivo studies, 200 μl of CM from the ALS iPSCs (CS07 and CS053) was injected subcutaneously into the ALS model mice (transgenic for the human SOD1 G93A mutation). Animal agility and strength, muscle innervation and mass, neurological score, onset of paralysis and lifespan of the ALS mice were assayed. After observing significant disease-modifying effects, the CM was characterized biochemically by fractionation, comparative proteomics, and epigenetic screens for the dependence on pluripotency. CM of fibroblasts that were differentiated from the wt hiPSCs lacked any neuroprotective activity and was used as a negative control throughout the studies. Results The secretome of PSCs including the ALS patient iPSCs was neuroprotective in the H 2 O 2 model. In the model with pathogenic SOD1 mutation, ALS iPSC-CM attenuated all examined hallmarks of ALS pathology, rescued human ALS-MNs from denervation and death, restored mitochondrial health, and reduced the expression of inflammatory genes. The ALS iPSC-CM also improved neuro-muscular health and function, and delayed paralysis and morbidity in ALS mice. Compared side by side, cyclosporine (CsA), a mitochondrial membrane blocker that prevents the leakage of mitochondrial DNA, failed to avert the death of ALS-MNs, although CsA and ALS iPSC-CM equally stabilized MN mitochondria and attenuated inflammatory genes. Biochemical characterization, comparative proteomics, and epigenetic screen all suggested that it was the interactome of several key proteins from different fractions of PSC-CM that delivered the multifaceted neuroprotection. Conclusions This work introduces and mechanistically characterizes a new biologic for treating ALS and other complex neurodegenerative diseases.
Effect of neoadjuvant chemotherapy on the immune microenvironment in gastric cancer as determined by multiplex immunofluorescence and T cell receptor repertoire analysis
Authors: Xiaofang Xing, Jinyao Shi, Yongning Jia, Yunsheng Dou, Zhongwu Li, Bin Dong, Ting Guo, Xiaojing Cheng, Xiaomei Li, Hong Du, Ying Hu, Shuqin Jia, Jian Zhang, Ziyu Li, Jiafu Ji
Journal: Journal for ImmunoTherapy of Cancer (2022)

The combination of immune checkpoint blockade and chemotherapy has revolutionized the treatment of advanced gastric cancer (GC). It is crucial to unravel chemotherapy-induced tumor microenvironment (TME) modulation and identify which immunotherapy would improve antitumor effect.
THE WEEKEND EFFECT ON OUTCOMES IN PATIENTS PRESENTING WITH ACUTE AORTIC DISSECTION: A NATIONWIDE ANALYSIS
Authors: Mohammad Altujjar, Mohammed Mhanna, Sapan Bhuta, Neha Patel, Michael D. Miedema, Jesse Manunga, Kerrilynn Hennessey, Stanislav Henkin, Bruce Wayne Andrus, Cynthia C. Taub, Mark A. Creager, Kevin M. Harris
Journal: Journal of the American College of Cardiology (2022)
DETERMINANTS OF MORTALITY AMONG SENIORS ACUTELY READMITTED FOR HEART FAILURE: RACIAL DISPARITIES AND CLINICAL CORRELATIONS
Authors: Tuoyo O. Mene-Afejuku, Gini P. Jeyashanmugaraja, Mahfuz Hoq, Olatunde Ola, Amit J. Shah
Journal: Journal of the American College of Cardiology (2022)
TRULY ZERO FLUOROSCOPY ABLATION OF RIGHT SIDED SUPRA-VENTRICULAR TACHYCARDIAS IN PEDIATRIC PATIENTS
Authors: Carlos E. Guzman, Mauricio Cortes-Aguirre, Carla Gabriela Guzman-Moreno, Edgar Francisco Carrizales-Sepúlveda, Ivan Lopez-Alcocer
Journal: Journal of the American College of Cardiology (2022)
ASSOCIATION BETWEEN BLOOD TYPE AND OUTCOMES OF BRIDGE-TO-TRANSPLANT LEFT VENTRICULAR ASSIST DEVICE THERAPY: ANALYSIS OF THE UNITED NETWORK FOR ORGAN SHARING (UNOS) REGISTRY
Authors: Veraprapas Kittipibul, Vanessa Blumer, Josephine Harrington, Stephen Greene, Robert John Mentz, Chetan B. Patel, Stuart D. Russell, Richa Agarwal
Journal: Journal of the American College of Cardiology (2022)
RECURRENT CARDIAC MYXOMA COMPLICATED BY BRAIN METASTASES: ROLE OF MULTIMODALITY IMAGING IN DIAGNOSIS AND MANAGEMENT
Authors: Ryan Kabir, Syed Z. Qamer, Shahrad Shadman, Itsik Ben-Dor, Michael C. Slack, Christian Charles Shults, Vikram Nayar, Benjamin Weinberg, Ana Barac
Journal: Journal of the American College of Cardiology (2022)
ASSOCIATION OF FRAILTY WITH LONG-TERM STROKE AND BLEEDING RISK IN OLDER PATIENTS WITH NON-VALVULAR ATRIAL FIBRILLATION: THE SHIZUOKA STUDY
Authors: Shiori Nishimura, Hiraku Kumamaru, Satoshi Shoji, Eiji Nakatani, Hiroyuki Yamamoto, Nao Ichihara, Yoshiki Miyachi, Hiroaki Miyata, Shun Kohsaka
Journal: Journal of the American College of Cardiology (2022)
Longitudinal TNFR1 and TNFR2 and Kidney Outcomes: Results from AASK and VA NEPHRON-D
Authors: Teresa K. Chen, Steven G. Coca, Michelle M. Estrella, Lawrence J. Appel, Josef Coresh, Heather Thiessen Philbrook, Wassim Obeid, Linda F. Fried, Hiddo J.L. Heerspink, Joachim H. Ix, Michael G. Shlipak, Paul L. Kimmel, Chirag R. Parikh, Morgan E. Grams
Journal: Journal of the American Society of Nephrology (2022)

Significance Statement Recent research suggests that biomarkers of the TNF pathway (TNFR1 and TNFR2) are associated with worse kidney outcomes. Most of these studies, however, evaluated baseline levels rather than longitudinal changes. In two cohorts (AASK, which enrolled Black people with CKD attributed to hypertension, and VA NEPHRON-D, which enrolled veterans with albuminuric CKD and type 2 diabetes), greater longitudinal increases in serum or plasma TNFR1 and TNFR2 were associated with higher risks of ESKD in AASK and subsequent kidney function decline in VA NEPHRON-D. These associations were independent of baseline biomarker level and kidney function. Longitudinal trajectories in TNFR1 and TNFR2 may ultimately allow improved risk assessment for kidney failure in persons with CKD. Background Higher baseline levels of soluble TNF receptors (TNFR1 and TNFR2) have been associated with progressive CKD. Whether longitudinal changes in these biomarkers of inflammation are also associated with worse kidney outcomes has been less studied. Methods We evaluated associations of longitudinal changes in TNFR1 and TNFR2 with ESKD in the African American Study of Kidney Disease and Hypertension (AASK; 38% female; 0% diabetes) and kidney function decline (first occurrence of ≥30 ml/min per 1.73 m 2 or ≥50% eGFR decline if randomization eGFR ≥60 or &lt;60 ml/min per 1.73 m 2 , respectively; ESKD) in the Veterans Affairs Nephropathy in Diabetes trial (VA NEPHRON-D; 99% male; 100% diabetes) using Cox models. Biomarkers were measured from samples collected at 0-, 12-, and 24-month visits for AASK (serum) and 0- and 12-month visits for VA NEPHRON-D (plasma). Biomarker slopes (AASK) were estimated using linear mixed-effects models. Covariates included sociodemographic/clinical factors, baseline biomarker level, and kidney function. Results There were 129 ESKD events over a median of 7.0 years in AASK ( n =418) and 118 kidney function decline events over a median of 1.5 years in VA NEPHRON-D ( n =754). In AASK, each 1 SD increase in TNFR1 and TNFR2 slope was associated with 2.98- and 1.87-fold higher risks of ESKD, respectively. In VA NEPHRON-D, each 1 SD increase in TNFR1 and TNFR2 was associated with 3.20- and 1.43-fold higher risks of kidney function decline, respectively. Conclusions Among individuals with and without diabetes, longitudinal increases in TNFR1 and TNFR2 were each associated with progressive CKD, independent of initial biomarker level and kidney function.
Point-of-Care Ultrasonography: Clearly More Than a Pretty Picture
Authors: Hamid Shokoohi, Andrew S. Liteplo, Irene W. Y. Ma
Journal: JAMA Internal Medicine (2022)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Internal Medicine HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Internal Medicine journal
Conversational Artificial Intelligence in Psychotherapy: A New Therapeutic Tool or Agent?
Authors: Jana Sedlakova, Manuel Trachsel
Journal: The American Journal of Bioethics (2022)

Conversational artificial intelligence (CAI) presents many opportunities in the psychotherapeutic landscape—such as therapeutic support for people with mental health problems and without access to care. The adoption of CAI poses many risks that need in-depth ethical scrutiny. The objective of this paper is to complement current research on the ethics of AI for mental health by proposing a holistic, ethical, and epistemic analysis of CAI adoption. First, we focus on the question of whether CAI is rather a tool or an agent. This question serves as a framework for the subsequent ethical analysis of CAI focusing on topics of (self-) knowledge, (self-)understanding, and relationships. Second, we propose further conceptual and ethical analysis regarding human-AI interaction and argue that CAI cannot be considered as an equal partner in a conversation as is the case with a human therapist. Instead, CAI's role in a conversation should be restricted to specific functions.
THE COMPARATIVE EFFICACY OF INCLISIRAN, PCSK9 INHIBITING MONOCLONAL ANTIBODIES, AND EZETIMIBE FOR THE TREATMENT OF HIGH CHOLESTEROL IN ADULTS WITH OR AT RISK OF ASCVD: A SYSTEMATIC LITERATURE REVIEW AND NETWORK META-ANALYSIS
Authors: Caresse Campbell, Nihar R. Desai, Batul Electricwala, Robert Stoekenbroek, Yuting Kuang, Arianna Nevo, Hsiu-Ching Chang, Jennifer Uyei, Joaquim Cristino
Journal: Journal of the American College of Cardiology (2022)
Abstract P4-07-20: Survival analysis using the entire transcriptome to pinpoint biomarkers with the highest prognostic power
Authors: Balazs Gyorffy
Journal: Cancer Research (2022)

Abstract Introduction. Extensive research is directed to uncover new biomarkers capable to stratify breast cancer patients into clinically relevant cohorts. However, the overall performance ranking of such marker candidates compared to other genes is virtually absent. Here, we present the ranking of all survival related genes in chemotherapy treated basal and estrogen positive/HER2 negative breast cancer. Methods. We searched the GEO repository to uncover transcriptomic datasets with available follow-up and clinical data. After quality control and normalization, samples entered an integrated database. Molecular subtypes were designated using gene expression data. Survival analysis was performed using Cox proportional hazards regression. False discovery rate was computed to combat multiple hypothesis testing. Kaplan-Meier plots were drawn to visualize the best performing genes. Results. The entire database includes 7,830 unique samples from 55 independent datasets. Of those with available relapse-free survival time, 3,382 samples were estrogen receptor-positive and 696 were basal. In chemotherapy treated ER positive/ERBB2 negative patients the significant prognostic biomarker genes achieved hazard rates between 1.76 and 3.33 with a p value below 5.8E-04. The significant prognostic genes in adjuvant chemotherapy treated basal breast cancer samples reached hazard rates between 1.88 and 3.61 with a p value below 7.2E-04. Finally, an online accessible platform utilizing the entire database was set up enabling the validation of future biomarker candidates. Conclusions. A reference ranking for all genes in two chemotherapy treated breast cancer cohorts is presented. The results help to neglect those with unlikely clinical significance and to focus future research on the most promising candidates. Citation Format: Balazs Gyorffy. Survival analysis using the entire transcriptome to pinpoint biomarkers with the highest prognostic power [abstract]. In: Proceedings of the 2021 San Antonio Breast Cancer Symposium; 2021 Dec 7-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2022;82(4 Suppl):Abstract nr P4-07-20.
Impact of neutropenia on clinical manifestations and outcome of Staphylococcus aureus bloodstream infection: a propensity score-based overlap weight analysis in two large, prospectively evaluated cohorts
Authors: Johannes Camp, Tim Filla, Lina Glaubitz, Achim J. Kaasch, Frieder Fuchs, Matt Scarborough, Hong Bin Kim, Robert Tilley, Chun-Hsing Liao, Jonathan Edgeworth, Emmanuel Nsutebu, Luis Eduardo López-Cortés, Laura Morata, Martin J. Llewelyn, Vance G. Fowler, Guy Thwaites, Harald Seifert, Winfried V. Kern, Siegbert Rieg
Journal: Clinical Microbiology and Infection (2022)
PSMA-targeting TGFβ-insensitive armored CAR T cells in metastatic castration-resistant prostate cancer: a phase 1 trial
Authors: Vivek Narayan, Julie S. Barber-Rotenberg, In-Young Jung, Simon F. Lacey, Andrew J. Rech, Megan M. Davis, Wei-Ting Hwang, Priti Lal, Erica L. Carpenter, Shannon L. Maude, Gabriela Plesa, Neha Vapiwala, Anne Chew, Michael Moniak, Ronnie A. Sebro, Michael D. Farwell, Amy Marshall, Joan Gilmore, Lester Lledo, Karen Dengel, Sarah E. Church, Tyler D. Hether, Jun Xu, Mercy Gohil, Thomas H. Buckingham, Stephanie S. Yee, Vanessa E. Gonzalez, Irina Kulikovskaya, Fang Chen, Lifeng Tian, Kyle Tien, Whitney Gladney, Christopher L. Nobles, Hayley E. Raymond, Diane Frazee, Mary Truran, Elizabeth Veloso, Holly McConville, Jonathan Aguedelo, Samantha Hower, Sophia Ngo, Julie Jadlowsky, J. Joseph Melenhorst, Aoife Roche, John Everett, Minnal Gupta, Farzana Nazimuddin, Chelsie Bartoszek, Natalka Koterba, Rachael Reynolds, Farris Ellington, Christopher C. Kloss, Jihyun Lee, Yangbing Zhao, John Scholler, James L. Riley, Christina Bailey, Andrew White, Briana Hudson, Pearl Chang, Marcela V. Maus, Bruce L. Levine, Elizabeth O. Hexner, Donald L. Siegel, Frederic D. Bushman, Carl H. June, Joseph A. Fraietta, Naomi B. Haas
Journal: Nature Medicine (2022)
Global mortality burden attributable to non-optimal temperatures
Authors: Ana M Vicedo-Cabrera, Aurelio Tobias, Jouni J K Jaakkola, Yasushi Honda, Masahiro Hashizume, Yuming Guo, Joel Schwartz, Antonella Zanobetti, Michelle L Bell, Ben Armstrong, Klea Katsouyanni, Andy Haines, Kristie L Ebi, Antonio Gasparrini
Journal: The Lancet (2022)