SOME ASPECTS OF ADRENAL CORTICAL FUNCTION AND PITUITARY-ADRENAL RELATIONSHIPS
Authors: M. S. S.
Journal: Annals of Internal Medicine (1949)

Editorial1 November 1949SOME ASPECTS OF ADRENAL CORTICAL FUNCTION AND PITUITARY-ADRENAL RELATIONSHIPSM. S. S.M. S. S.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-31-5-925 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn April, 1949 Hench et al.1reported that the administration of one of the adrenal cortical hormones, 17-hydroxy-11-dehydrocorticosterone (Compound E), produced beneficial effects of a striking nature in a group of patients with advanced rheumatoid arthritis. Withdrawal of the hormone was followed by the recurrence of signs and symptoms of the disease. Essentially similar results were obtained in several patients who were given adrenocorticotropic hormone (ACTH) derived from hog pituitary. In a subsequent paper2these investigators reported that the administration of compound E to three patients with acute rheumatic fever was also followed by rapid subsidence of clinical evidences of...1 HENCHKENDALLSLOCUMBPOLLEY PEECCHHF: The effect of a hormone of the adrenal cortex (17-hydroxy-11-dehydrocorticosterone: compound E) and of pituitary adrenocorticotropic hormone on rheumatoid arthritis; preliminary report, Proc. Staff Meet. Mayo Clinic, 1949, xxiv, 181. Google Scholar2 HENCHSLOCUMBBARNESSMITHPOLLEYKENDALL PECHARHLHFEC: The effects of the adrenal cortical hormone 17-hydroxy-11-dehydrocorticosterone (compound E) on the acute phase of rheumatic fever: preliminary report, Proc. Staff Meet. Mayo Clinic, 1949, xxiv, 277. Google Scholar3 THORNBAYLESMASSELLFORSHAMHILLSMITHWARREN GWTBBFPHSRSJE: Studies on the relation of pituitary-adrenal function to rheumatic disease, N. Eng. Jr. Med., 1949, ccxli, 529. 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Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byNewer concepts of the role of sodium in diseaseADRENAL CORTEX IN LIVER DISEASE*JOHN JOSEPH WEBSTER, M.D., F.A.C.P.Relation of the Adrenal Cortex to Rheumatic Disease: A Review of Some Recent Investigations 1 November 1949Volume 31, Issue 5Page: 925-931KeywordsAdrenocorticotropic hormoneHormonesProlactinRheumatic feverRheumatoid arthritisSigns and symptoms ePublished: 1 December 2008 Issue Published: 1 November 1949 PDF downloadLoading ...