tbuckley/cabot-search huggingface dataset:
Transmission of SARS-CoV-2 by children: a rapid review, 30 December 2019 to 10 August 2020
Authors: Barbara Clyne, Karen Jordan, Susan Ahern, Kieran A Walsh, Paula Byrne, Paul G Carty, Linda Drummond, Kirsty K O’Brien, Susan M Smith, Patricia Harrington, Máirín Ryan, Michelle O’Neill
Journal: Eurosurveillance (2022)

Background The role of children in the transmission of SARS-CoV-2 during the early pandemic was unclear. Aim We aimed to review studies on the transmission of SARS-CoV-2 by children during the early pandemic. Methods We searched MEDLINE, Embase, the Cochrane Library, Europe PubMed Central and the preprint servers medRxiv and bioRxiv from 30 December 2019 to 10 August 2020. We assessed the quality of included studies using a series of questions adapted from related tools. We provide a narrative synthesis of the results. Results We identified 28 studies from 17 countries. Ten of 19 studies on household and close contact transmission reported low rates of child-to-adult or child-to-child transmission. Six studies investigated transmission of SARS-CoV-2 in educational settings, with three studies reporting 183 cases from 14,003 close contacts who may have contracted COVID-19 from children index cases at their schools. Three mathematical modelling studies estimated that children were less likely to infect others than adults. All studies were of low to moderate quality. Conclusions During the early pandemic, it appeared that children were not substantially contributing to household transmission of SARS-CoV-2. School-based studies indicated that transmission rates in this setting were low. Large-scale studies of transmission chains using data collected from contact tracing and serological studies detecting past evidence of infection would be needed to verify our findings.
Pneumococcal and Influenza Vaccination Levels Among Adults Aged ≥65 Years—United States, 1995
Journal: JAMA (1997)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Association of β-Blocker Use at Time of Radical Prostatectomy With Rate of Treatment for Prostate Cancer Recurrence
Authors: Shivanthe Sivanesan, Kristin Austlid Taskén, Helene Hartvedt Grytli
Journal: JAMA Network Open (2022)

The perioperative period has gained attention as a window of opportunity to prevent cancer recurrence. Evidence in support of a role for nonselective β-blockers (nsBBs) in cancer treatment is increasing, and counteracting cancer recurrence associated with perioperative stress and catecholamine is one of the suggested mechanisms of action.
New Names
Journal: JAMA (1980)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Gynecology of Childhood and Adolescence
Authors: Vincent J. Capraro
Journal: JAMA (1968)

Here for the first time the physician interested in gynecologic problems in children and adolescents, be he pediatrician, gynecologist, general practitioner, or other specialist, can find most of the current thinking in this fast-developing field. This work of 574 pages is the most extensive book on the subject, and since 40% of the population in the United States is less than 18 years of age, it is quite timely. The relevant literature, culled by Dr. Huffman, has been condensed to dovetail with the author's tremendous experience and vast clinical knowledge. Some chapters have a bibliography of over 200 references, and can serve as a source of the latest information in pediatric and adolescent gynecology. There is a good balance between practical diagnostic and therapeutic points and theoretic and etiologic considerations. The background pathology is very well covered. The book is logically divided and proper space is given to such areas
Genetic inactivation of Semaphorin 3C protects mice from acute kidney injury
Authors: Anxiang Cai, Guanyu Ye, Sandrine Placier, Perrine Frère, Brigitte Surin, Sophie Vandermeersch, Raphael Kormann, Yi-Chun Xu-Dubois, Magali Genest, Morgane Lannoy, Christos E. Chadjichristos, Jean-Claude Dussaule, Peter J. Scambler, Christos Chatziantoniou, Amélie Calmont
Journal: Kidney International (2022)
THE PATHWAY OF INFECTION IN POLIOMYELITIS
Authors: P. W. C.
Journal: Annals of Internal Medicine (1941)

Editorial1 August 1941THE PATHWAY OF INFECTION IN POLIOMYELITISP. W. C.P. W. C.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-15-2-329 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe problem of the pathogenesis of poliomyelitis—its portal of entry, the manner of the distribution of the virus in the body tissues and the route by which it is disseminated—has not yet been satisfactorily solved, in spite of much intensive investigation.The study of the disease is beset with many practical difficulties. One of the greatest of these is the fact that the monkey is the only animal susceptible to the filtrable virus which causes the disease, and successful inoculation of these animals is the only method of demonstrating its presence. Even monkeys appear to differ in susceptibility, and individual...1 LEVADITIKLINGHORNUS CCG: Transmission expérimentale de la poliomyélite par la voie digestive, Compt. rend. Soc. de biol., 1933, cxii, 43-45. Google Scholar2 FLEXNER S: Respiratory versus gastrointestinal infection in poliomyelitis, Jr. Exper. Med., 1936, lxiii, 209-226. CrossrefGoogle Scholar3 TRASKPAULVIGNEC JDJRAJ: I. Poliomyelitic virus in human stools, Jr. Exper. Med., 1940, lxxi, 751-764. CrossrefGoogle Scholar4 PAULTRASKGARD JRJDS: II. Poliomyelitic virus in urban sewage, Jr. Exper. Med., 1940, lxxi, 765-778. CrossrefGoogle Scholar5 SABINWARD ABR: The natural history of human poliomyelitis. I. Distribution of virus in nervous and non-nervous tissues, Jr. Exper. Med., 1941, lxxiii, 771-794. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 August 1941Volume 15, Issue 2Page: 329-332KeywordsInoculationPathogenesisPoliomyelitis ePublished: 1 December 2008 Issue Published: 1 August 1941 PDF downloadLoading ...
BOOK REVIEWS
Authors: V. R. SHEIDLER
Journal: JNCI Journal of the National Cancer Institute (1990)

BOOK REVIEWS Get access Diagnosis and Management of Pain in Patients with Cancer . Ronald Kanner , ed. Basel , Switzerland : S. Karger , 1988 , 104 pp.$46. VIVIAN R. SHEIDLER VIVIAN R. SHEIDLER The Johns Hopkins Oncology Center 600 N. Wolfe St.Rm. 132 Baltimore, MD 21205 Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 82, Issue 2, 17 January 1990, Page 147, https://doi.org/10.1093/jnci/82.2.147 Published: 17 January 1990
Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer
Authors: Aftab Alam, Eric Levanduski, Parker Denz, Helena Solleiro Villavicencio, Maulasri Bhatta, Lamees Alhorebi, Yali Zhang, Eduardo Cortes Gomez, Brian Morreale, Sharon Senchanthisai, Jun Li, Steven G Turowski, Sandra Sexton, Sheila Jani Sait, Prashant K Singh, Jianmin Wang, Anirban Maitra, Pawel Kalinski, Ronald A DePinho, Huamin Wang, Wenting Liao, Scott I Abrams, Brahm H Segal, Prasenjit Dey
Journal: Cancer Cell (2022)
Miscellanea Medica
Journal: JAMA (1993)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Divergent SARS-CoV-2 Omicron–reactive T and B cell responses in COVID-19 vaccine recipients
Authors: Corine H. GeurtsvanKessel, Daryl Geers, Katharina S. Schmitz, Anna Z. Mykytyn, Mart M. Lamers, Susanne Bogers, Sandra Scherbeijn, Lennert Gommers, Roos S. G. Sablerolles, Nella N. Nieuwkoop, Laurine C. Rijsbergen, Laura L. A. van Dijk, Janet de Wilde, Kimberley Alblas, Tim I. Breugem, Bart J. A. Rijnders, Herbert de Jager, Daniela Weiskopf, P. Hugo M. van der Kuy, Alessandro Sette, Marion P. G. Koopmans, Alba Grifoni, Bart L. Haagmans, Rory D. de Vries
Journal: Science Immunology (2022)

The severe acute respiratory distress syndrome coronavirus 2 (SARS-CoV-2) Omicron variant is spreading rapidly, even in vaccinated individuals, raising concerns about immune escape. Here, we studied neutralizing antibodies and T cell responses targeting SARS-CoV-2 D614G [wild type (WT)] and the Beta, Delta, and Omicron variants of concern in a cohort of 60 health care workers after immunization with ChAdOx-1 S, Ad26.COV2.S, mRNA-1273, or BNT162b2. High binding antibody levels against WT SARS-CoV-2 spike (S) were detected 28 days after vaccination with both mRNA vaccines (mRNA-1273 or BNT162b2), which substantially decreased after 6 months. In contrast, antibody levels were lower after Ad26.COV2.S vaccination but did not wane. Neutralization assays showed consistent cross-neutralization of the Beta and Delta variants, but neutralization of Omicron was significantly lower or absent. BNT162b2 booster vaccination after either two mRNA-1273 immunizations or Ad26.COV2 priming partially restored neutralization of the Omicron variant, but responses were still up to 17-fold decreased compared with WT. SARS-CoV-2-specific T cells were detected up to 6 months after all vaccination regimens, with more consistent detection of specific CD4
估计个体日晒量的不同方法
Journal: British Journal of Dermatology (2022)

Journal Article 估计个体日晒量的不同方法 Get access British Journal of Dermatology, Volume 186, Issue 2, 1 February 2022, Page e97, https://doi.org/10.1111/bjd.20925 Published: 01 February 2022
Alpine altitude climate treatment for severe and uncontrolled asthma: An EAACI position paper
Authors: Karin B. Fieten, Marieke T. Drijver‐Messelink, Annalisa Cogo, Denis Charpin, Milena Sokolowska, Ioana Agache, Luís Manuel Taborda‐Barata, Ibon Eguiluz‐Gracia, Gerrit J. Braunstahl, Sven F. Seys, Maarten van den Berge, Konrad E. Bloch, Silvia Ulrich, Carlos Cardoso‐Vigueros, Jasper H. Kappen, Anneke ten Brinke, Markus Koch, Claudia Traidl‐Hoffmann, Pedro da Mata, David J. Prins, Suzanne G. M. A. Pasmans, Sarah Bendien, Maia Rukhadze, Mohamed H. Shamji, Mariana Couto, Hanneke Oude Elberink, Diego G. Peroni, Giorgio Piacentini, Els J. M. Weersink, Matteo Bonini, Lucia H. M. Rijssenbeek‐Nouwens, Cezmi A. Akdis
Journal: Allergy (2022)

Currently available European Alpine Altitude Climate Treatment (AACT) programs combine the physical characteristics of altitude with the avoidance of environmental triggers in the alpine climate and a personalized multidisciplinary pulmonary rehabilitation approach. The reduced barometric pressure, oxygen pressure, and air density, the relatively low temperature and humidity, and the increased UV radiation at moderate altitude induce several physiological and immunological adaptation responses. The environmental characteristics of the alpine climate include reduced aeroallergens such as house dust mites (HDM), pollen, fungi, and less air pollution. These combined factors seem to have immunomodulatory effects controlling pathogenic inflammatory responses and favoring less neuro-immune stress in patients with different asthma phenotypes. The extensive multidisciplinary treatment program may further contribute to the observed clinical improvement by AACT in asthma control and quality of life, fewer exacerbations and hospitalizations, reduced need for oral corticosteroids (OCS), improved lung function, decreased airway hyperresponsiveness (AHR), improved exercise tolerance, and improved sinonasal outcomes. Based on observational studies and expert opinion, AACT represents a valuable therapy for those patients irrespective of their asthma phenotype, who cannot achieve optimal control of their complex condition despite all the advances in medical science and treatment according to guidelines, and therefore run the risk of falling into a downward spiral of loss of physical and mental health. In the light of the observed rapid decrease in inflammation and immunomodulatory effects, AACT can be considered as a natural treatment that targets biological pathways.
Association Between Tick Bites and Alpha-gal Syndrome: A Case-Control Study
Authors: Johanna Salzer, Alison Binder, Emma Jones, Brad Biggerstaff, Paige Armstrong, Kristen Nichols Heitman, Shailesh Choudhary, Charles Beard, Lyle Petersen, Scott Commins, Gilbert Kersh
Journal: Journal of Allergy and Clinical Immunology (2022)
MEDICAL PROGRESS.
Journal: JAMA (1889)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Battered women: not-so-hot lines
Authors: N. Cunningham
Journal: JAMA (1993)

<h3>In Reply.</h3> —I thank Drs Abromovitz, Frazier, Kelleher, Rothschild, and Weintraub for their interest and comments. Their letters offer an opportunity to reemphasize several points, and my colleagues and I invite them all to join us in seeking better evidence regarding the accuracy and usefulness of the history and physical examination. There are several parallel but different ways to think about test accuracy, and different ones are being adopted by different generations of clinicians. None is inherently better than any other and some of the writers call attention to the advantages and disadvantages of various statistics. These points are discussed in greater detail by Sackett in his introductory article to the series on the rational clinical examination.<sup>1</sup> We are unaware of data on the reproducibility or validity of the tests proposed by Dr Abromovitz. Some recent studies challenge the role of facet joints as a common cause of back
Prevalence of Common Infectious Diseases After COVID-19 Vaccination and Easing of Pandemic Restrictions in Israel
Authors: Shimon Amar, Yonat Shemer Avni, Norm O’Rourke, Tal Michael
Journal: JAMA Network Open (2022)

Social restrictions intended to limit the transmission of SARS-CoV-2 may have also been associated with decreased rates of other communicable diseases. Evidence suggests that infection incidence rates (IRs) are rebounding after easing of social restrictions (eg, mask mandates). The reemergence of infectious disease complicates efforts to manage the ongoing COVID-19 pandemic.To examine IRs of frequently occurring infectious diseases after a successful SARS-CoV-2 vaccination campaign in Israel and cessation of social restrictions.This cross-sectional study was conducted using records for respiratory and gastrointestinal infectious diseases at 209 community clinics in southern Israel from 2017 to 2021. Included patients attended community clinics from January 1, 2017, to June 30, 2021.Incidence of infectious diseases was estimated in the first 3 months after the easing of social restrictions (ie, April-June 2021) across age groups.Age-specific and disease-specific weekly IRs per 100 000 population for April to June were compared between 2017 and 2021 and expected current IR was estimated using segmented linear regression. Growth rates of respiratory infections across years and weekly diagnoses detected by real-time polymerase chain reaction testing were also compared.Among 386 711 patients with a total of 1 221 568 visits to community clinics, the mean (SD) age was 27.29 (23.93) years, and there were 202 494 (52.3%) male patients and 184 217 (47.7%) female patients. Children aged 0 to 3 years had significantly increased rates of respiratory and gastrointestinal infection diagnoses (IR ratio, 2.64; 95% CI, 2:30-2.91; P < .001). In addition, incidence of non-SARS-CoV-2 respiratory infections were significantly increased across age groups (IR ratio, 1.74; 95% CI, 1.56-1.94; P < .001).These morbidity trends observed in Israel suggest that similar trends could occur in coming months in other countries after easing of COVID-19-related restrictions, particularly with the ongoing challenges of SARS-CoV-2 variants.
Clinical Chemistry, New York
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal