tbuckley/cabot-search huggingface dataset:
Statistical uncertainty quantification to augment clinical decision support: a first implementation in sleep medicine
Authors: Dae Y. Kang, Pamela N. DeYoung, Justin Tantiongloc, Todd P. Coleman, Robert L. Owens
Journal: npj Digital Medicine (2021)

Machine learning has the potential to change the practice of medicine, particularly in areas that require pattern recognition (e.g. radiology). Although automated classification is unlikely to be perfect, few modern machine learning tools have the ability to assess their own classification confidence to recognize uncertainty that might need human review. Using automated single-channel sleep staging as a first implementation, we demonstrated that uncertainty information (as quantified using Shannon entropy) can be utilized in a "human in the loop" methodology to promote targeted review of uncertain sleep stage classifications on an epoch-by-epoch basis. Across 20 sleep studies, this feedback methodology proved capable of improving scoring agreement with the gold standard over automated scoring alone (average improvement in Cohen's Kappa of 0.28), in a fraction of the scoring time compared to full manual review (60% reduction). In summary, our uncertainty-based clinician-in-the-loop framework promotes the improvement of medical classification accuracy/confidence in a cost-effective and economically resourceful manner.
Use of Aspirin During Pregnancy to Prevent Preeclampsia
Authors: Jill Jin
Journal: JAMA (2021)

US Preventive Services Task Force; Karina W. Davidson, PhD, MASc; Michael J. Barry, MD; Carol M. Mangione, MD, MSPH; Michael Cabana, MD, MA, MPH; Aaron B. Caughey, MD, PhD; Esa M. Davis, MD, MPH; Katrina E. Donahue, MD, MPH; Chyke A. Doubeni, MD, MPH; Martha Kubik, PhD, RN; Li Li, MD, PhD, MPH; Gbenga Ogedegbe, MD, MPH; Lori Pbert, PhD; Michael Silverstein, MD, MPH; Melissa A. Simon, MD, MPH; James Stevermer, MD, MSPH; Chien-Wen Tseng, MD, MPH, MSEE; John B. Wong, MD
1816P CHEK2 gene somatic loss in breast tumors from carriers of germline CHEK2 mutations
Authors: A. Iyevleva, S. Aleksakhina, A. Sokolenko, S. Baskina, A. Venina, E. Anisimova, I.V. Bizin, A.O. Ivantsov, E.N. Imyanitov
Journal: Annals of Oncology (2021)
Two ST11 <i>Klebsiella pneumoniae</i> strains exacerbate colorectal tumorigenesis in a colitis-associated mouse model
Authors: Ming-Ko Chiang, Pei-Yi Hsiao, Yen-Yi Liu, Hui-Ling Tang, Chien-Shun Chiou, Min-Chi Lu, Yi-Chyi Lai
Journal: Gut Microbes (2021)

Sequence type (ST) 11 is one of the major lineages of carbapenem-resistant Klebsiella pneumoniae (CRKP). Although the gastrointestinal (GI) carriage of CRKP predisposes individuals to subsequent infections, little is known for its impact on gut homeostasis. In this study, we investigated the association between ST11 CRKP colonization and colorectal cancer (CRC). Two ST11 CRKP, KPC160111 (KL47) and KPC160132 (KL64), were selected as the representative strains. We used azoxymethane (AOM) and dextran sodium sulfate (DSS) to initiate a colitis-associated CRC model. Both strains established prolonged colonization in the GI tract of the AOM-DSS-treated BALB/c mice and aggravated gut dysbiosis. Under this AOM-DSS-induced setting, ST11 K. pneumoniae colonization significantly promoted the growth and progression of colorectal adenomas to high-grade dysplasia. Numerous crypts were formed inside the enlarged adenomas, in which CD163+ tumor-associated macrophages accumulated. Similarly, ST11 K. pneumoniae also increased the population size of the CD163+ macrophages with the M2 phenotype in the peritoneal cavity of LPS-primed BALB/c mice. When applied to RAW264.7 cells, ST11 K. pneumoniae polarized the macrophages toward an M2 phenotype through the inhibition of IKK-NFκB and the activation of STAT6-KLF4-IL-10. Through the M2-skewing ability, ST11 K. pneumoniae promoted the accumulation of CD163+ macrophages in the adenomatous crypts to create an immunosuppressive niche, which not only accommodated the extended stay for its own sake but also deteriorated colorectal tumorigenesis.
661P Conditional survival and 5-year follow-up in CheckMate 214: First-line nivolumab + ipilimumab (N+I) versus sunitinib (S) in advanced renal cell carcinoma (aRCC)
Authors: R.J. Motzer, N.M. Tannir, D.F. McDermott, M. Burotto, T.K. Choueiri, H.J. Hammers, E.R. Plimack, C.G. Porta, S. George, T.B. Powles, F. Donskov, H. Gurney, C.K. Kollmannsberger, M-O. Grimm, Y. Tomita, B.I. Rini, M.B. McHenry, C-W. Lee, B. Escudier
Journal: Annals of Oncology (2021)
Association of Early Blood Pressure Decrease and Renal Function With Prognosis in Acute Heart Failure
Authors: Yuya Matsue, Iziah E. Sama, Douwe Postmus, Marco Metra, Barry H. Greenberg, Gad Cotter, Beth A. Davison, G. Michael Felker, Gerasimos Filippatos, Peter Pang, Piotr Ponikowski, Thomas Severin, Claudio Gimpelewicz, Adriaan A. Voors, John R. Teerlink
Journal: JACC Heart Failure (2021)
1739P Survival outcomes in patients with sarcomatoid pleural mesothelioma: A retrospective analysis from the last two decades
Authors: R. Shah, M. Blasi, J. Kuon, P. Christopolous, I. Chung, A. Stenzinger, M. Kriegsmann, J. Glade, L.V. Klotz, M.E. Eichhorn, S. Wessels, T. Muley, F.J. Herth, H. Bischoff, M. Thomas
Journal: Annals of Oncology (2021)
23P Transcriptional profiling of circulating tumor and hybrid cells in breast cancer patients
Authors: E.V. Denisov, M.E. Menyailo, S.Y. Zolotareva, T.S. Gerashchenko, V.V. Alifanov, L.A. Tashireva, O.E. Savelieva, E.S. Grigoryeva, N.V. Cherdyntseva, V.M. Perelmuter
Journal: Annals of Oncology (2021)
1049P Clinical models to predict response in mucosal melanoma (MM) patients (pts) treated with anti-PD-1 (PD1) or combined with ipilimumab (PD1+IPI)
Authors: F. Dimitriou, K. Namikawa, P. Teterycz, I.L.M. Reijers, E. Buchbinder, J. Soon, L. Zimmer, M. Mooradian, M.G. Vitale, E. Armstrong, D. Johnson, J. Guo, C. Lebbe, C. Robert, M. Mandala, P. Bhave, M. Farid, K.C. Kähler, S. Lo, G.V. Long
Journal: Annals of Oncology (2021)
1533P Gene expression-based prediction of pazopanib benefit in sarcomas
Authors: A. Lassmann, C.E. Heilig, S.S. Mughal, S. Pirmann, A. Mock, C. Andresen, B. Aybey, S. Bauer, C. Brandts, P. Horak, D. Lipka, S. Kreutzfeldt, M.V. Teleanu, C. Heining, B. Brors, H. Glimm, D. Hübschmann, S. Fröhling
Journal: Annals of Oncology (2021)
1707P A single G-CSF administration is enough to limit neutropenia in patients treated by eribulin
Authors: A. Schmitt, M. Reda, P. Macaire, H. Bellio, L. Uwer, S.M. Ilie, V. Lorgis, A. Hennequin, S. Ladoire, E. Rederstorff, P. Fumoleau, N. Isambert, N. Bonnin, B. You, G. Freyer, I. Desmoulins
Journal: Annals of Oncology (2021)
Transposed Column Heads in Table
Authors: Thomas Martens, Roy Beck, Richard Bergenstal
Journal: JAMA (2021)

Elyse O. Kharbanda, MD, MPH; Jacob Haapala, MPH; Malini DeSilva, MD, MPH; Gabriela Vazquez-Benitez, PhD; Kimberly K. Vesco, MD, MPH; Allison L. Naleway, PhD; Heather S. Lipkind, MD, MS
66P Leptin receptor (Ob-R) and its association with tumour infiltrating lymphocytes (TILs) in early breast cancer (BC): Correlation with pathological complete response (pCR)
Authors: L. García Estevez, J. Palacios Calvo, M. Sampayo, I. Calvo, E. Díaz, B. Perez Míes, G. Moreno-Bueno
Journal: Annals of Oncology (2021)
937P Multicenter phase II trial of lenvatinib plus hepatic intra-arterial infusion chemotherapy with cisplatin for advanced hepatocellular carcinoma: LEOPARD
Authors: M. Ikeda, T. Yamashita, S. Ogasawara, M. Kudo, Y. Inaba, M. Morimoto, K. Tsuchiya, S. Shimizu, Y. Kojima, A. Hiraoka, K. Nouso, H. Aikata, K. Numata, T. Sato, T. Okusaka, J. Furuse
Journal: Annals of Oncology (2021)
LBA21 Radioembolization with chemotherapy for colorectal liver metastases: A randomized, open-label, international, multicenter, phase III trial (EPOCH study)
Authors: M.F. Mulcahy, R. Salem, A. Mahvash, M. Pracht, A.H. Montazeri, S. Bandula, K. Hermann, E. Brown, D. Zuckerman, G. Wilson, T-Y. Kim, A. Weaver, P. Ross, W.P. Harris, M.S. Johnson, C.T. Sofocleous, S.A. Padia, R.J. Lewandowski, E. Garin, P. Sinclair
Journal: Annals of Oncology (2021)
Association of Circulating Ketone Bodies With Functional Outcomes After ST-Segment Elevation Myocardial Infarction
Authors: Marie-Sophie L.Y. de Koning, B. Daan Westenbrink, Solmaz Assa, Erwin Garcia, Margery A. Connelly, Dirk J. van Veldhuisen, Robin P.F. Dullaart, Erik Lipsic, Pim van der Harst
Journal: Journal of the American College of Cardiology (2021)

Circulating ketone bodies (KBs) are increased in patients with heart failure (HF), corresponding with increased cardiac KB metabolism and HF severity. However, the role of circulating KBs in ischemia/reperfusion remains unknown.This study sought to investigate longitudinal changes of KBs and their associations with functional outcomes in patients presenting with ST-segment elevation myocardial infarction (STEMI).KBs were measured in 369 participants from a randomized trial on early metformin therapy after STEMI. Nonfasting plasma concentrations of KBs (β-hydroxybutyrate, acetoacetate, and acetone) were measured by nuclear magnetic resonance spectroscopy at presentation, at 24 hours, and after 4 months. Myocardial infarct size and left ventricular ejection fraction (LVEF) were determined by cardiac magnetic resonance imaging at 4 months. Associations of circulating KBs with infarct size and LVEF were determined using multivariable linear regression analyses.Circulating KBs were high at presentation with STEMI (median total KBs: 520 μmol/L; interquartile range [IQR]: 315-997 μmol/L). At 24 hours after reperfusion, KBs were still high compared with levels at 4-month follow-up (206 μmol/L [IQR: 174-246] vs 166 μmol/L [IQR: 143-201], respectively; P < 0.001). Increased KB concentrations at 24 hours were independently associated with larger myocardial infarct size (total KBs, per 100 μmol/L: β = 1.56; 95% confidence interval: 0.29-2.83; P = 0.016) and lower LVEF (β = -1.78; 95% CI: (-3.17 to -0.39; P = 0.012).Circulating KBs are increased in patients presenting with STEMI. Higher KBs at 24 hours are associated with functional outcomes after STEMI, which suggests a potential role for ketone metabolism in response to myocardial ischemia. (Metabolic Modulation With Metformin to Reduce Heart Failure After Acute Myocardial Infarction: Glycometabolic Intervention as Adjunct to Primary Coronary Intervention in ST Elevation Myocardial Infarction (GIPS-III): a Randomized Controlled Trial; NCT01217307).
1224P Systematic review and meta-analysis of immunotherapy effectiveness for pretreated patients with non-small cell lung cancer harboring EGFR exon 20 insertions
Authors: P. Christopoulos, S-H.I. Ou, J. Lin, D. Berg, J-L. Hong, Y. Yin, J. Lin, V. Bunn, H.M. Lin, M. Mehta, M. Thomas
Journal: Annals of Oncology (2021)
E. coli and the etiology of human PBC: Antimitochondrial antibodies and spreading determinants
Authors: Yao Yang, Jinjung Choi, Ying Chen, Pietro Invernizzi, Guoxiang Yang, Weici Zhang, Ti‐hong Shao, Frank Jordan, Natalia S. Nemeria, Ross L. Coppel, William M. Ridgway, Mark Kurth, Aftab A. Ansari, Patrick S.C. Leung, M. Eric Gershwin
Journal: Hepatology (2021)

The increased frequency of urinary tract infections in patients with primary biliary cholangitis (PBC) and the cross-reactivity between the lipoyl domains (LD) of human pyruvate dehydrogenase complex (hPDC-E2) and Escherichia coli PDC-E2 (ePDC-E2) have long suggested a role of E. coli in causality of PBC. This issue, however, has remained speculative. We hypothesized that by generating specific constructs of human and E. coli PDC-E2, we would be able to assess the specificity of autoantibody responses and define whether exposure to E. coli in susceptible hosts is the basis for the antimitochondrial antibody (AMA) response.Importantly, the reactivity of hPDC-E2 LD (hPDC-E2LD) affinity-purified antibodies against hPDC-E2LD could only be removed by prior absorption with hPDC-E2LD and not ePDC-E2, suggesting the presence of unique human PDC-E2 epitopes distinct from E. coli PDC-E2. To identify the autoepitope(s) present in hPDC-E2LD, a more detailed study using a variety of PDC-E2 constructs was tested, including the effect of lipoic acid (LA) on ePDC-E2 conformation and AMA recognition. Individual recombinant ePDCE2 LD domains LD1, LD2 and LD3 did not react with either AMA or antibodies to LA (anti-LA), but in contrast, anti-LA was readily reactive against purified recombinant LD1, LD2, and LD3 expressed in tandem (LP); such reactivity increased when LP was precultured with LA. Moreover, when the three LD (LD1, LD2, LD3) domains were expressed in tandem in pET28a or when LD1 was expressed in another plasmid pGEX, they were lipoylated and reactive to PBC sera.In conclusion, our data are consistent with an exposure to E. coli that elicits specific antibody to ePDC-E2 resulting in determinant spreading and the classic autoantibody to hPDC-E2LD. We argue this is the first step to development of human PBC.
338TiP CAPItello-292: A phase 1b/3 study of capivasertib, palbociclib and fulvestrant versus placebo, palbociclib and fulvestrant in HR+/HER2− advanced breast cancer
Authors: E. Hamilton, G. Schiavon, L.M. Grinsted, E.C. De Bruin, M.T. Catanese, H.S. Rugo
Journal: Annals of Oncology (2021)
CCNE1 copy number is a biomarker for response to combination WEE1-ATR inhibition in ovarian and endometrial cancer models
Authors: Haineng Xu, Erin George, Yasuto Kinose, Hyoung Kim, Jennifer B. Shah, Jasmine D. Peake, Benjamin Ferman, Sergey Medvedev, Thomas Murtha, Carter J. Barger, Kyle M. Devins, Kurt D’Andrea, Bradley Wubbenhorst, Lauren E. Schwartz, Wei-Ting Hwang, Gordon B. Mills, Katherine L. Nathanson, Adam R. Karpf, Ronny Drapkin, Eric J. Brown, Fiona Simpkins
Journal: Cell Reports Medicine (2021)

CCNE1-amplified ovarian cancers (OVCAs) and endometrial cancers (EMCAs) are associated with platinum resistance and poor survival, representing a clinically unmet need. We hypothesized that dysregulated cell-cycle progression promoted by CCNE1 overexpression would lead to increased sensitivity to low-dose WEE1 inhibition and ataxia telangiectasia and Rad3-related (ATR) inhibition (WEE1i-ATRi), thereby optimizing efficacy and tolerability. The addition of ATRi to WEE1i is required to block feedback activation of ATR signaling mediated by WEE1i. Low-dose WEE1i-ATRi synergistically decreases viability and colony formation and increases replication fork collapse and double-strand breaks (DSBs) in a CCNE1 copy number (CN)-dependent manner. Only upon CCNE1 induction does WEE1i perturb DNA synthesis at S-phase entry, and addition of ATRi increases DSBs during DNA synthesis. Inherent resistance to WEE1i is overcome with WEE1i-ATRi, with notable durable tumor regressions and improved survival in patient-derived xenograft (PDX) models in a CCNE1-level-dependent manner. These studies demonstrate that CCNE1 CN is a clinically tractable biomarker predicting responsiveness to low-dose WEE1i-ATRi for aggressive subsets of OVCAs/EMCAs.
386O Exploratory biomarker analysis of DESTINY-CRC01, a phase II, multicenter, open-label study of trastuzumab deruxtecan (T-DXd, DS-8201) in patients (pts) with HER2-expressing metastatic colorectal cancer (mCRC)
Authors: S. Siena, K. Raghav, T. Masuishi, K. Yamaguchi, T. Nishina, E. Elez, J. Rodriguez, I. Chau, M. Di Bartolomeo, H. Kawakami, F. Suto, K. Kobayashi, M. Koga, K. Inaki, Y. Kuwahara, I. Takehara, A. Grothey, T. Yoshino
Journal: Annals of Oncology (2021)
125P Cognitive impairment in breast cancer patients up to 18 months after cancer treatments: The French multicentric longitudinal CANTO-Cog cohort substudy
Authors: F. Joly Lobbedez, I. Hardy-Léger, S. Lefevre Arbogast, O. Rigal, J. Le Fel, B. Pistilli, J. Petrucci, C. Lévy, A. Capel, C. Coutant, F. Lerebours, L. Vanlemmens, E. Bourbouloux, I. Vaz-Luis, A-L. Martin, S. Everhard, F. André, C. Charles, S. Dauchy, M. Lange
Journal: Annals of Oncology (2021)
Light blue crest sign visualized by magnifying endoscopy in normal colonic mucosa
Authors: Cong Yuan, Xue-Mei Lin, Hui-Li Zhu, Yan Ou, Qian Cheng, Jun-Xiu Li, Juan Liao
Journal: Endoscopy (2021)

Light blue crest (LBC), defined as a fine, blue-white line on the crests of the epithelial surface/gyri, is always discerned at the edge of marginal crypt epithelium [1]. The optical sign has high specificity for the endoscopic identification of gastric intestinal metaplasia [1]. It can only be visualized by magnifying endoscopy with narrow-band imaging or blue-laser imaging, and is caused by the reflectance of short-wavelength light (400–430 nm) on the microvillous surface of the epithelium [1] [2]. LBC is naturally seen in normal small intestine due to regular microvilli arrangement [1]. Herein, we describe the LBC sign in normal colonic mucosa.
CN21 Experience in the management of PICCs (peripherally inserted central catheter) by nurses in an onco-hematologic day hospital: Activity, indications and complications
Authors: M.S. Mancha, L. Pagès, M. Duque, S. Bravo, C. Sevilla, M. Granero, A. Pérez, M.A. Valverde, A. Rios, A. Manzana, S. Saborit, F. Losa
Journal: Annals of Oncology (2021)
Perceptions of adolescents and young adults with allergy and/or asthma and their parents on EAACI guideline recommendations about transitional care: A European survey
Authors: Ekaterina Khaleva, Rebecca Knibb, Audrey DunnGalvin, Marta Vazquez‐Ortiz, Pasquale Comberiati, Cherry Alviani, Teresa Garriga‐Baraut, Mary Hazel Gowland, Claudia Gore, Elizabeth Angier, Katharina Blumchen, Bettina Duca, Valérie Hox, Britt Jensen, Charlotte G. Mortz, Helena Pite, Oliver Pfaar, Alexandra F. Santos, Silvia Sanchez‐Garcia, Frans Timmermans, Graham Roberts
Journal: Allergy (2021)

The European Academy of Allergy and Clinical Immunology has developed a guideline to provide evidence-based recommendations for healthcare professionals to support the transitional care of adolescents and young adults (AYA) with allergy and/or asthma. The goal of this work was to ensure that the draft recommendations are also important for patients.We surveyed patients aged 11-25 years with allergy and/or asthma and their parents across Europe between 17 February and 16 March 2020. The multilingual survey was distributed through national allergy and asthma patient organizations in Europe as well as through social media.A total of 1210 responses from 24 European countries were collected. There were 415 (34.3%) AYA and 795 (65.7%) parents. The majority of AYA (72.3%) and parents (81.9%) were female. Patients had a history of asthma (61.1%), allergic rhinoconjunctivitis (54.1%), food allergy (53.8%), atopic eczema (42.6%) and anaphylaxis (28.8%). All recommendations achieved the median score of either 'important' or 'very important'. The least supported recommendations were the use of joint clinics with both paediatric and adult physicians attending and the use of web-based or mobile technologies for communication with the AYA. The most supported recommendation was checking that the AYA is knowledgeable and compliant with their prescribed medication. Qualitative analysis revealed conditional approval for some recommendations.There was agreement from patients and parents on the importance of the draft recommendations on transitional care for AYA with allergy and/or asthma and their parents. The recommendations now need to be implemented into clinical practice across Europe.
1413P Antibiotic administration and outcome of patients with advanced gastric cancer receiving programmed death-1 inhibitors or with single-agent chemotherapy
Authors: M. Jung, C.G. Kim, S-J. Shin, M. Hong, H.C. Chung, S.Y. Rha, H.S. Kim, C-K. Lee, J.H. Lee, Y. Han, H. Kim, J.H. Kim, S.Y. Lee, H-C. Jeung
Journal: Annals of Oncology (2021)
Implantable nerve guidance conduits: Material combinations, multi-functional strategies and advanced engineering innovations
Authors: Yixin Yan, Ruotong Yao, Jingyuan Zhao, Kaili Chen, Lirong Duan, Tian Wang, Shujun Zhang, Jinping Guan, Zhaozhu Zheng, Xiaoqin Wang, Zekun Liu, Yi Li, Gang Li
Journal: Bioactive Materials (2021)

Nerve guidance conduits (NGCs) have attracted much attention due to their great necessity and applicability in clinical use for the peripheral nerve repair. Great efforts in recent years have been devoted to the development of high-performance NGCs using various materials and strategies. The present review provides a comprehensive overview of progress in the material innovation, structural design, advanced engineering technologies and multi functionalization of state-of-the-art nerve guidance conduits NGCs. Abundant advanced engineering technologies including extrusion-based system, laser-based system, and novel textile forming techniques in terms of weaving, knitting, braiding, and electrospinning techniques were also analyzed in detail. Findings arising from this review indicate that the structural mimetic NGCs combined with natural and synthetic materials using advanced manufacturing technologies can make full use of their complementary advantages, acquiring better biomechanical properties, chemical stability and biocompatibility. Finally, the existing challenges and future opportunities of NGCs were put forward aiming for further research and applications of NGCs.
Abstract 12035: Effect of 10-minute Dispatch-Assisted Cardiopulmonary Resuscitation Training in Addition to a Standard Course: A Simulation Study
Authors: Hidetada Fukushima, Hideki Asai, Kazunobu Norimoto, Tadahiko Seki, Yasuyuki Kawai, Kazuo Okuchi
Journal: Circulation (2015)

Introduction: Immediate bystander cardiopulmonary resuscitation (CPR) is essential for the good outcome of sudden cardiac arrest victims. Current guidelines recommend dispatch-assisted CPR (DA-CPR), which can double the frequency of bystander CPR. Laypersons, however, are not familiar with how dispatchers provide CPR instructions. DA-CPR training may be effective at spreading DA-CPR, but this needs to be validated. The aim of this study was to determine the effectiveness of brief DA-CPR training in addition to a standard CPR training course. Methods: We conducted a DA-CPR simulation study. Participants with no prior CPR training within 1 year were assigned randomly to one of two 90-min CPR training courses (DA-CPR Group: a standard CPR course with 10-min DA-CPR training or Standard Group: a standard CPR course with a simple introduction to how dispatchers deal with emergency calls). In the DA-CPR Group, the participants practiced the role of a dispatcher and an emergency caller. At 6 months after training, the subjects performed CPR for 2 min under instruction from off-duty dispatchers. Results: Of the 66 participants, 59 (DA-CPR Group, 30; Standard Group, 29) completed the simulation at 6 months after training. The median time intervals between call receipt and cardiac arrest recognition or instruction for chest compressions by dispatchers were similar between both groups. However, the subjects in the DA-CPR Group provided the first compression more quickly (median time interval between call receipt and the first dispatch-assisted compression: 108 vs. 129 s, respectively, p &lt; 0.05 Mann-Whitney U test). The quality of chest compressions was, however, similar between both groups. Conclusions: All participants could perform DA-CPR at 6 months after training, but those in the DA-CPR Group started chest compressions more quickly. DA-CPR training might be effective for the immediate development of better cooperation between a layperson and a dispatcher.
697P Impact of β-blockers (BB) on outcomes of metastatic renal cell carcinoma (mRCC) patients treated with nivolumab (N)
Authors: C. Alves Costa Silva, L. Derosa, C. Dalban, E. Colomba, S. Negrier, C.M. Chevreau, G. Gravis, S.M. Oudard, B. Laguerre, P. Barthelemy, D. Borchiellini, M. Gross-Goupil, L. Geoffrois, F. Rolland, A. Thiery-Vuillemin, F. Joly, S. Ladoire, F. Tantot, B. Escudier, L. Albiges
Journal: Annals of Oncology (2021)