tbuckley/cabot-search huggingface dataset:
Education for self-treatment by adult asthmatics
Authors: L. A. Maiman
Journal: JAMA (1979)

A prospective experimental design evaluated the ability of a series of educational and motivational interventions to enhance self-treatment by adult asthmatics and to reduce use of emergency department services for asthma attacks. After treatment for an asthma attack, subjects were randomly assigned to the following sequential interventions: (1) reinforcement by interpersonal similarity at the time of the emergency visit, (2) receipt of positive written appeals, and (3) follow-up telephone reinforcement. The asthmatic nurse educator was generally more effective in achieving short-term reduction of emergency department visits. Although the usefulness of the positive written appeal increased when employed by the asthmatic nurse, there were no substantive independent effects of the written message on emergency department use. (<i>JAMA</i>241:1919-1922, 1979)
Association News
Authors: M. L. Harris
Journal: JAMA (1910)

<h3>DATE OF NEXT SESSION</h3><h3>Suggestions Desired by Board of Trustees Concerning Los Angeles Session, 1911</h3> The date of the next session of the American Medical Association, to be held in Los Angeles, California, is a matter of considerable importance. The great distance which a majority of those who attend will be obliged to travel, and the length of time necessarily consumed in the journey, make it more essential than usual that the date be the one which shall accommodate the greatest number of those who desire to attend. That several of the members are already taking an interest in the matter is evidenced by a number of letters on the subject which the Chairman of the Board of Trustees has received recently and he takes this opportunity not only to acknowledge their receipt but also to express his thanks to the writers thereof for their views thus presented. It seems to be generally recognized that the first week in June is not a desirable time
Comprehensive biochemistry. Section I: Physico-chemical and organic aspects of biochemistry. Vol. 4: Separation methods.
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Palpable Breast Masses
Authors: Daniel B. Kopans
Journal: JAMA (1981)

Mammography has a significant role to play before any breast surgery is performed. Ten cases are described to illustrate five benefits: (1) confirm the presence of an evident neoplasm, (2) define the three breast masses that do not require biopsy, (3) demonstrate ipsilateral multicentricity of breast cancer, (4) discover occult contralateral cancer, and (5) detect occult malignant neoplasia elsewhere in a breast having a mass excised or reconstruction performed. (<i>JAMA</i>1981;246:2819-2822)
All stenoses are not equal: Angiographic renal artery stenosis severity does not predict trans-lesional pressure gradient Robert J. Lederman, Stanley J. Chetcuti, Paul M. Grossman, Julian J. Esteban, Ann Luciano, Steven W. Werns, Mauro Moscucci, Eric R. Bates. University of Michigan Health System, Ann Arbor, MI
Journal: Journal of the American College of Cardiology (2001)
ITALY
Journal: JAMA (1952)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Response to Comment on Meek et al. Reappearance of C-Peptide During the Third Trimester in Type 1 Diabetes Pregnancy: Pancreatic Regeneration or Fetal Hyperinsulinism? Diabetes Care 2021;44:1826–1834
Authors: Claire L. Meek, Richard A. Oram, Timothy J. McDonald, Denice S. Feig, Andrew T. Hattersley, Helen R. Murphy
Journal: Diabetes Care (2022)
The Stereoscope in Ophthalmology, with Especial Reference to the Treatment of Heterophoria and Heterotropia. Designed to Accompany the Phoro-Optometer Stereoscope and the Wells Selection of Stereoscopic Charts.
Journal: JAMA (1918)

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Coronary flow velocity reserve as a predictor of left ventricular volume and functional change after acute myocardial infarction Seung-Jea Tahk, Myeong-Ho Yoon, Joon-Han Shin, Zhe-Xun Lilan, So-Yeon Choi, Hyuk_Jae Han-Soo Kim, Byung-il W. Choi. Ajou University, Suwon, South Korea
Journal: Journal of the American College of Cardiology (2001)
COVID‐19 Session
Authors: S Mahil, N Dand, K Mason, Z Yiu, T Tsakok, F Meynell, B Coker, H Mcateer, L Moorhead, T Mackenzie, P Calzavara Pinton, R Rivera, E Mahe, A Carugno, M Magnano, G Rech, E Balogh, S Feldman, D Mcmahon, E Freeman, P Gisondi, L Puig, R Warren, P Meglio, S Langan, F Capon, C Griffiths, J Barker, C Smith, A D'cruz, F Mason, R D'souza, J Freitas, J Thomas, M Saha
Journal: British Journal of Dermatology (2020)

Psoriasis is a common immune-mediated inflammatory skin disease with frequent multimorbidity, and immunosuppressants are the mainstay of treatment in moderate-to-severe disease.An understanding of the impact of COVID-19 on individuals with psoriasis and the effect of psoriasis therapies on the course of COVID-19 is urgently required to inform clinical decision-making.This study sought to characterize the clinical course of COVID-19 in patients with psoriasis and to identify factors associated with hospitalization.Clinicianreported cases of confirmed or suspected COVID-19 in psoriasis were collected via an international online registry.Multivariable-adjusted logistic regression identified factors associated with hospitalization.Patient risk-mitigating behaviours were characterized using an independent global selfreport registry.In total, 334 clinician-reported cases (median age 50 years, 62% male, median body mass index 28 kg m -2 , 85% white) from 22 countries [most frequently, the U.K. (35%), Italy (22%) and Spain (16%)] were available between 27 March and 20 June 2020.Altogether, 245 (73.3%) patients were receiving a biologic, 54 (16.2%) a nonbiologic and 31 (9.3%) no systemic treatment.Overall, 311 (93.1%) achieved a full recovery, 71 (21.2%) were hospitalized and nine (2.7%) died.Risk factors associated with hospitalization were older age [adjusted odds ratio (aOR) 1.71, 95% confidence interval (CI) 1.26-2.32],male sex (aOR 2.37, 95% CI 1.11-5.04)and nonwhite ethnicity (aOR 3.40, 95% CI 1.27-9.11), in addition to chronic lung disease (aOR 4.37, 95% CI 1.62-11.74)and hypertension (aOR 2.23, 95% CI 1.05-4.74).Reduced risk of hospitalization was associated with use of a biologic (aOR 0.42, 95% CI 0.18-0.98)vs. nonbiological systemic therapy.There was no difference in risk of hospitalization between classes of biologics.An independent selfreport psoriasis registry (1167 patients from 39 countries) suggested increased social isolation (76% vs. 66%; P < 0.05) but similar nonadherence to medication (18% vs 22%) in patients receiving biologics vs. nonbiological systemic treatments.In this international moderate-to-severe psoriasis case series, most patients fully recovered from COVID-19; older age, being male and being of nonwhite ethnicity increased risk of hospitalization.Use of biologics, when compared with nonbiological systemic therapies, was associated with reduced risk of hospitalization; however, this requires further study owing to potential selection bias and unmeasured confounding such as a difference in risk-mitigating behaviours.
A comparison of risankizumab with fumaric acid esters for treating psoriasis
Journal: British Journal of Dermatology (2022)

Abstract Linked Article: Thaçi et al. Br J Dermatol 2022; 186:30–39. Patients with moderate to severe psoriasis that has failed to be controlled by topical therapy (applied directly to the skin) or ultraviolet light often require more intensive treatment. One such treatment is the oral drug fumaric acid esters (FAEs), which has been in use for at least 30 years, especially in Germany. A range of injectable drugs (‘biologics') have been developed more recently that target particular molecules involved in psoriasis inflammation. One of these is risankizumab (Skyrizi®) that targets interleukin 23. In this study, from several centres in Germany, the authors have conducted a controlled study comparing FAEs with risankizumab. Adult patients with moderate to severe psoriasis who had not previously received systemic treatment, were randomly assigned to each group (60 in each). Patients were monitored for response to treatment and side-effects for 24 weeks. The results showed that risankizumab was superior to FAEs in every respect. It produced earlier and greater improvement in psoriasis that persisted until the end of the observation period. In addition, risankizumab produced fewer side-effects than FAEs. Furthermore, the study showed that risankizumab was superior to FAEs in improving psoriasis of the nails, scalp, palms and soles, areas of the body that often respond less well to treatment. Linked Article: Thaçi et al. Br J Dermatol 2022; 186:30–39.
From the Editor's Desk
Journal: JAMA (1974)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
RT-CMR Imaging for Noninvasive Characterization of HFpEF
Authors: Sören J. Backhaus, Simon F. Rösel, Alexander Schulz, Torben Lange, Kristian Hellenkamp, Roman J. Gertz, Rolf Wachter, Michael Steinmetz, Shelby Kutty, Uwe Raaz, Tim Friede, Tim Seidler, Martin Uecker, Gerd Hasenfuß, Andreas Schuster
Journal: JACC. Cardiovascular imaging (2022)
SARS‐CoV‐2 causes Covid Toes
Journal: British Journal of Dermatology (2020)

Covid toes' are being seen with increasing frequency in children and young adults during the COVID-19 pandemic.Patients present with reddish or purple lesions (affected skin patches) located on the hands and/or feet, particularly fingers and toes.Detailed descriptions of biopsies of Covid toes have not been reported, and the virus called coronavirus SARS-CoV-2, which causes the disease COVID-19, has not been firmly established as the cause yet as most of the patients are negative for SARS-CoV-2 conventional tests (in which samples are taken from the nose and/or mouth).We examined skin biopsies from seven paediatric (child) patients presenting with Covid toes during the COVID-19 pandemic in Madrid, Spain.The presence of coronavirus SARS-CoV-2 was investigated by electron microscopy and immunohistochemistry (staining that uses an antibody to recognise the virus).Our findings demonstrated the presence of vascular (blood vessel) damage and SARS-CoV-2 viral particles within the damaged endothelial cells (internal layer of blood vessels).Although the clinical features, meaning those seen outwardly, and histopathological features, meaning those seen in tissue samples, were similar to conventional chilblains, which are caused by cold temperatures, the presence of viral particles in the blood vessels and the evidence of vascular damage, support the idea that SARS-CoV-2 causes the lesions.Vascular damage caused by the virus could be a key mechanism to explain Covid toes and perhaps also other types of lesions seen in patients severely affected by COVID-19.These findings can also help us to find a treatment focused on avoiding the vascular damage caused by the virus.
Endpoints for extraintestinal manifestations in inflammatory bowel disease trials: the EXTRA consensus from the International Organization for the Study of Inflammatory Bowel Diseases
Authors: Lucas Guillo, Maria Abreu, Remo Panaccione, William J Sandborn, Valderilio F Azevedo, Lianne Gensler, Bahar Moghaddam, Vineet Ahuja, Sabrina A Ali, Matthieu Allez, Ashwin N Ananthakrishnan, Abhik Bhattacharya, Marla Dubinsky, Anne Griffiths, Ailsa Hart, Burton Korelitz, Paulo G Kotze, Ioannis E Koutroubakis, Peter L Lakatos, James O Lindsay, Fernando Magro, Gerassimos J Mantzaris, Siew C Ng, Colm O'Morain, Julian Panés, Tommaso Parigi, Zhihua Ran, Gerhard Rogler, David T Rubin, David B Sachar, Britta Siegmund, Flavio Steinwurz, Curt Tysk, Stephan Vavricka, Sofia G Verstraete, Antoine P Brezin, Anna K Haemel, Axel Dignass, Bruce E Sands, Silvio Danese, Laurent Peyrin-Biroulet
Journal: The Lancet. Gastroenterology & hepatology (2022)
Feasibility of adjuvant S-1 chemotherapy after major hepatectomy for biliary tract cancers: An exploratory subset analysis of JCOG1202.
Authors: Shogo Kobayashi, Kohei Nakachi, Masafumi Ikeda, Masaru Konishi, Gakuto Ogawa, Katsuhiko Uesaka, Hiroaki Yanagimoto, Soichiro Morinaga, Hiroshi Wada, Kazuaki Shimada, Yu Takahashi, Toshio Nakagohri, Kunihito Gotoh, Ken Kamata, Yasuhiro Shimizu, Tetsuo Ajiki, Yasuyuki Kawamoto, Makoto Ueno, Takuji Okusaka, Junji Furuse
Journal: Journal of Clinical Oncology (2022)

408 Background: JCOG1202 (UMIN000011688) is a randomized phase III trial conducted in patients (pts) with biliary tract cancers (BTCs) that showed the superiority of adjuvant S-1, in terms of the overall survival (OS). Previous reports have suggested that major hepatectomy (MH) may affect the dose intensity as well as frequency of adverse events (AEs) and reduce the treatment efficacy of chemotherapy, due to impaired liver function and drug metabolism. Therefore, we investigated whether MH might affect the feasibility of adjuvant S-1 chemotherapy. Methods: Among the 440 pts enrolled in the JCOG1202 study, 207 pts who received adjuvant S-1 were included in this analysis. We compared the rate of treatment completion, the frequency of AEs, and the dose intensity of adjuvant S-1 after MH versus non-major hepatectomy (NMH). MH was defined as right hemi-hepatectomy, right trisectionectomy, left trisectionectomy, and central bi-sectionectomy, with or without pancreatoduodenectomy. Results: Of the 207 pts, 42 pts had undergone MH and 165 pts had undergone NMH. The primary cancers in the MH group were mainly intrahepatic cholangiocarcinoma and hilar cholangiocarcinoma. The pretreatment characteristics of the pts were as follows: performance status 0 (MH vs. NMH: 81.0% vs. 89.1%), biliary reconstruction (performed: 81.0% vs. 82.4%), time from hepatectomy to initiation of adjuvant S-1 therapy (median: 60 vs. 57 days), platelet count (17.7 vs. 23.4 x 10 4 /μL), and serum albumin (3.5 vs. 3.8 g/dL). The treatment completion proportion was lower in the MH group as compared to the NMH group (59.5% vs. 75.8%; treatment completion ratio, 0.786 (95% CI, 0.603-1.023), p = 0.0733), and the median dose intensity was lower in the MH group than in the NMH group (90% vs. 100%, p = 0.0358). The proportion of pts who discontinued adjuvant S-1 due to occurrence of AEs in the MH group vs. the NMH group was 23.8% vs. 10.3%. The major reasons for treatment discontinuation were biliary infection, nausea/vomiting, and diarrhea; these AEs were mainly observed in the first cycle; the frequency of grade 3-4 biliary infection during adjuvant S-1 therapy was 19.0% in the MH group versus 4.2% in the NMH group. Conclusions: In regard to adjuvant S-1 therapy for pts with resected BTC, the treatment completion proportion and dose intensity were lower in the MH group as compared to the NMH group. Caution should be exercised against the development of biliary infections during postoperative adjuvant S-1 therapy after MH in BTC pts.
GP73 is a glucogenic hormone contributing to SARS-CoV-2-induced hyperglycemia
Authors: Luming Wan, Qi Gao, Yongqiang Deng, Yuehua Ke, Enhao Ma, Huan Yang, Haotian Lin, Huilong Li, Yilong Yang, Jing Gong, Jingfei Li, Yixin Xu, Jing Liu, Jianmin Li, Jialong Liu, Xuemiao Zhang, Linfei Huang, Jiangyue Feng, Yanhong Zhang, Hanqing Huang, Huapeng Wang, Changjun Wang, Qi Chen, Xingyao Huang, Qing Ye, Dongyu Li, Qiulin Yan, Muyi Liu, Meng Wei, Yunhai Mo, Dongrui Li, Ke Tang, Changqing Lin, Fei Zheng, Lei Xu, Gong Cheng, Peihui Wang, Xiaopan Yang, Feixang Wu, Zhiwei Sun, Chengfeng Qin, Congwen Wei, Hui Zhong
Journal: Nature Metabolism (2022)
Circulation, New York
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Food for thought during school closures
Authors: None The Lancet Diabetes & Endocrinology
Journal: The Lancet Diabetes & Endocrinology (2020)

Since March, 2020, countries around the world have imposed nationwide school closures in an attempt to help reduce the burden of COVID-19. Ensuring that children safely return to the classroom at the start of the new school year has been a top priority for many nations in the northern hemisphere. Unfortunately, school attendance has been patchy, with schools in areas with high infection rates remaining closed. In other places, entire year groups have been asked to self-isolate for 14 days if a positive case is found in the same year group or contact bubble.
Dermatofibrosarcoma Protuberans Guidelines
Authors: Stanley J Miller, Murad Alam, James Andersen, Daniel Berg, Christopher K Bichakjian, Glen Bowen, Richard T Cheney, Frank Glass, Roy C Grekin, James M Grichnik, Anne Kessinger, Nancy Y Lee, Stuart Lessin, Daniel D Lydiatt, Lawrence W Margolis, Jeffrey Michalski, Kishwer S Nehal, Paul Nghiem, Allan R Oseroff, E William Rosenberg, Ashok R Shaha, Ronald J Siegle, Marshall M Urist
Journal: Journal of the National Comprehensive Cancer Network (2007)

Dermatofibrosarcoma protuberans (DFSP) is an uncommon, low-grade sarcoma of fibroblast origin with an incidence rate of 0.8 cases per million persons each year. Although it rarely metastasizes, initial misdiagnosis, prolonged time to accurate diagnosis, and large tumor size at diagnosis are common. These updated 2007 guidelines include changes in recommendations for considering radiation therapy, as well as those regarding surgical margins in some patients. For the most recent version of the guidelines, please visit NCCN.org
Why do longer in-stent restenosis lesions have a higher recurrence rate? A serial intravascular ultrasound analysis Javed M. Ahmed, Gary S. Mintz, Ron Waksman, Neil J. Weissman, Lowell F. Satler, Kenneth M. Kent, Augusto D. Pichard. Washington Hospital Center, Washington D.C., DC
Journal: Journal of the American College of Cardiology (2001)
CORRECTION
Journal: JAMA (1928)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal