tbuckley/cabot-search huggingface dataset:
FLT3 OR CD33 NOT EMCN Logic Gated CAR-NK Cell Therapy (SENTI-202) for Precise Targeting of AML
Authors: Brian S. Garrison, Han Deng, Gozde Yucel, Nicholas W. Frankel, Marcela Guzman-Ayala, Russell Gordley, Michelle Hung, Derrick Lee, Marcus Gainer, Kathryn Loving, Jenny Chien, Tiffany Pan, Wesley Gorman, Nelia Leemans, Alice Lam, Travis Wood, Wilson Wong, Philip Lee, Tim Lu, Gary Lee
Journal: Blood (2021)
Safety, Pharmacokinetics and Preliminary Efficacy of HMPL-523 in Adult Patients with Primary Immune Thrombocytopenia: A Randomized, Double-Blind and Placebo-Controlled Phase 1b Study
Authors: Renchi Yang, Hu Zhou, Yu Hu, Jie Yin, Junmin Li, Wenming Chen, Ruibin Huang, Yuping Gong, Chenwei Luo, Liu Xiaofan, Heng Mei, Bingjie Ding, Chengyuan Gu, Huiping Sun, Leng Yun, Dexiang Ji, Yan Li, Haiyan Shi, Hongyan Yin, Songhua Fan, Jian Wang, Weiguo Su
Journal: Blood (2021)
A Cross-Sectional Analysis of County-Level Social Vulnerability and Physical Frailty Among Adults with Hematological Malignancies
Authors: Shakira J. Grant, Allison M. Deal, Hillary M. Heiling, Kirsten A Nyrop, Hyman B Muss, Samuel M. Rubinstein, Eben I Lichtman, Tanya M. Wildes, Sascha A. Tuchman
Journal: Blood (2021)
Classical Hodgkin Lymphoma; Real-World Observations from Physicians, Patients, and Caregivers on the Disease and Its Treatment (CONNECT): Observations of Physicians on Treatment and Interim PET-Adapted Regimens
Authors: Susan K. Parsons, Kristina S. Yu, Nicholas Liu, Supriya Kumar, Michelle A. Fanale, Katie Holmes, Carlos Flores, Andy Surinach, Darcy R. Flora, Andrew M. Evens
Journal: Blood (2021)
Abstract 9196: Innocuous Levels of Pulmonary Thrombosis Protect Against Inflammatory Lung Injury via Endothelial Arachidonate 15-Lipoxygenase and Hypoxia-Inducible Factor 1α
Authors: Colin E Evans, Xianming Zhang, Narsa Machireddy, Youyang Zhao
Journal: Circulation (2021)

Introduction: Sepsis patients commonly suffer from lung thrombosis and sepsis-induced acute lung injury (ALI), but clinical trials of anti-coagulants in sepsis and ALI have failed, and the impact of varying severities of lung thrombosis on ALI is unknown. Hypothesis: Pulmonary thrombosis regulates the severity of sepsis-induced ALI through modulation of pulmonary endothelial cell (EC) viability. In this study, we aimed to determine the impact of varying levels of lung thrombosis on ALI and to delineate the underlying mechanisms. Methods: We assessed inflammatory lung injury in mouse models of pulmonary thrombosis combined with sepsis-induced lung injury and thrombocytopenia. We also used RNA sequencing and nanoparticle-mediated EC-targeted gene editing to delineate and target thrombosis-induced EC signaling pathways. Results: In wild type mice, excessive increases in lung thrombosis worsened ALI, but the induction of a mild and innocuous level of lung thrombosis instead reduced ALI and mortality. We then showed that this mild level of lung thrombosis increases the expression of multiple factors that regulate cell survival, including arachidonate 15-lipoxygenase (Alox15) and hypoxia-inducible factor (HIF) 1α in ECs. Next, we used nanoparticle-mediated EC gene editing to show that the protective impact of mild lung thrombosis on ALI is dependent upon EC-specific Alox15 and HIF1α. From a therapeutic perspective, the mild level of lung thrombosis could be induced up to 8 hours after sepsis and still maintain its protective impact on ALI. Furthermore, the induction of mild lung thrombosis completely prevented thrombocytopenia-induced increases and ALI and mortality. Conclusions: Mild levels of lung thrombosis protect against inflammatory lung injury via EC Alox15 and HIF1α. Promoting lung EC survival through Alox15 or HIF1α signaling represents a promising therapeutic strategy against ALI.
A Retrospective Analysis of the Efficacy of Low-Dose Metronomic Cyclophosphamide for Treatment in Patients with Low Grade Non-Hodgkin Lymphoma
Authors: Boram Han, Bum Jun Kim, Ho Young Kim, Dae Young Zang, Hyun Lim, Ho Suk Kang, Jae Seung Soh, Hyo Jung Kim
Journal: Blood (2021)
JAK2-Negative Polycythemia: Underlying Causes, Including Novel Variants of Uncertain Significance - Real Life Data of 10 Years from a Tertiary Reference Center
Authors: Katarzyna Aleksandra Aleksandra Jalowiec, Kristina Vrotniakaite-Bajerciene, Noel Frey, Annina Capraru, Tatiana Wojtovicova, Raphael Joncourt, André Tichelli, Porret Naomi, Alicia Rovo
Journal: Blood (2021)
8 Multiparameter characterization of CAR T cells
Authors: Xueting Wang, Christina Pitzka, Daniela Rheindorf, Nadine Mockel-Tenbrinck, Tatjana Holzer, Anne Richter, Toni Cathomen, Cesar Evaristo
Journal: Journal for ImmunoTherapy of Cancer (2021)

Background Adoptive cell transfer of chimeric antigen receptor (CAR) modified T cells has demonstrated great therapeutic success against certain hematological malignancies. However, a substantial number of patients experienced relapse at some point after treatment with the underlying mechanisms not fully understood. Emerging data suggest that the undesired clinical outcome is related to different aspects, which include: the tumor heterogeneity, the tumor microenvironment, as well as intrinsic characteristics of the CAR T cells. In this work, we aimed to understand the diversity of CAR T cells generated from different donors, using multiparameter in vitro characterization. Methods Leukapheresis from healthy donors were collected to generate CAR T cells using the GMP-compliant CliniMACS Prodigy® platform, enabling an automated and closed engineering of CAR T cells in a highly reproducible manner. We performed an in-depth characterization of the resulting CAR T cells by exploring differences in the immunophenotype, cell fitness and effector function of the freshly prepared as compared to frozen CAR T cell samples. Specifically, we designed several flow cytometry panels for the extensive characterization of immunophenotypes of interest such as: proliferative capacity, differentiation, activation and exhaustion. Cell fitness status was determined by the rate at which cells undergo apoptosis following stress. Finally, effector function was determined by the ability of the activated CAR T cells to secrete proinflammatory cytokines including IFN-g, TNF-a and IL-2. The associations between these different parameters were analyzed using comprehensive statistical approaches. Results With our established workflow, over 20 healthy-donor derived CAR T cells were generated and characterized. We have observed donor-dependent variations and responses for most of the explored parameters. In general, the freezing and thawing process negatively affected cell fitness and effector function of the CAR T cells and resulted in altered immunophenotypes. Additionally, correlations between certain immunophenotypes and cell fitness/effector function were identified. Conclusions Collectively, we established a workflow for multiparameter characterization of CAR T cells and assessed the intrinsic variability of CAR T cells for both research and clinical application.
Lysosomal hydrolases of the epidermis.
Authors: P.D. MIER, JOSE J.M.A. HURK
Journal: British Journal of Dermatology (1976)

The activities of 14 acid hydrolases have been measured in normal and diseased human epidermis. Our findings were as follows: (i) Increased hydrolase activity was common in lesions; the clinically uninvolved skin of patients, however, invariably showed normal values. (2) The pattern of change was independent of the nature of the didease, the arylsulphatases and beta-glucosidase usually showing the greatest elevations. (3) The magnitude of the changes differed from disease to disease, being most marked in the lesions of psoriasis. (4) Ichthyosiform erythroderma was exceptional in showing elevated levels of the galactosidases and cathepsins B1 and D. We suggest that (with the exception of ichthyosiform erythroderma) the abnormalities which we have observed may be related to the proliferative rate of the epidermis.
Pomalidomide and Dexamethasone with or without Subcutaneous Daratumumab in Patients with Relapsed or Refractory Multiple Myeloma: Updated Analysis of the Phase 3 Apollo Study
Authors: Pieter Sonneveld, Evangelos Terpos, Mario Boccadoro, Sosana Delimpasi, Meral Beksac, Eirini Katodritou, Philippe Moreau, Luca Baldini, Argiris Symeonidis, Jelena Bila, Albert Oriol, Maria-Victoria Mateos, Hermann Einsele, Ioannis Orfanidis, Tobias Kampfenkel, Yanping Qiu, Himal Amin, Michele Kosh, NamPhuong Tran, Robin Carson, Meletios A. Dimopoulos
Journal: Blood (2021)
First in Human (FIH) FLT3 and SYK Inhibitor HM43239 Shows Single Agent Activity in Patients (pts) with Relapsed or Refractory (R/R) FLT3 Mutated and Wild-Type Acute Myeloid Leukemia (AML)
Authors: Naval Daver, Kyoo Hyung Lee, Chul Won Jung, Sung-Soo Yoon, Martha L. Arellano, Jiyeon Yoon, Nora Lee, Hyunjin Kim, Jaeyeon Lee, Brian A. Jonas, Seungjae Baek
Journal: Blood (2021)
Post-Transplant Cyclophosphamide in Acute Leukemia Patients Receiving More Than 5/10 HLA-Mismatched Allogeneic Stem Cell Transplantation: A Study on Behalf of the ALWP of the EBMT
Authors: Michele Wieczorek, Myriam Labopin, Luca Castagna, Eolia Brissot, Gerard Socié, Anna Maria Raiola, Emanuele Angelucci, Arancha Bermúdez, Ibrahim Yakoub-Agha, Mahmoud Aljurf, Charles Crawley, Jean-Baptiste Mear, Maurizio Musso, Renato Fanin, Daniele Avenoso, Pascal Turlure, Cristina Tecchio, Jaime Sanz, Fabio Ciceri, Arnon Nagler, Mohamad Mohty
Journal: Blood (2021)
Effect of nutritionally modified infant formula on academic performance: linkage of seven dormant randomised controlled trials to national education data
Authors: Maximiliane L Verfürden, Ruth Gilbert, Alan Lucas, John Jerrim, Mary Fewtrell
Journal: BMJ (2021)

Abstract Objective To compare differences in academic performance between adolescents who were randomised in infancy to modified or standard infant formula. Design Linkage of seven dormant randomised controlled trials to national education data. Setting Five hospitals in England, 11 August 1993 to 29 October 2001, and schools in England, September 2002 to August 2016. Participants 1763 adolescents (425 born preterm, 299 born at term and small for gestational age, 1039 born at term) who took part in one of seven randomised controlled trials of infant formula in infancy. Interventions Nutrient enriched versus standard term formula (two trials), long chain polyunsaturated fatty acid (LCPUFA) supplemented versus unsupplemented formula (two trials), high versus low iron follow-on formula (one trial), high versus low sn-2 palmitate formula (one trial), and nucleotide supplemented versus unsupplemented formula (one trial). Main outcome measures The primary outcome, determined by linkage of trial data to school data, was the mean difference in standard deviation scores for mandated examinations in mathematics at age 16 years. Secondary outcomes included differences in standard deviation scores in English (16 and 11 years) and mathematics (11 years). Analysis was by intention to treat with multiple imputation for participants missing the primary outcome. Results 1607 (91.2%) participants were linked to school records. No benefit was found for performance in mathematics examinations at age 16 years for any modified formula: nutrient enriched in preterm infants after discharge from hospital, standard deviation score 0.02 (95% confidence interval −0.22 to 0.27), and nutrient enriched in small for gestational age term infants −0.11 (−0.33 to 0.12); LCPUFA supplemented in preterm infants −0.19 (−0.46 to 0.08) and in term infants −0.14 (−0.36 to 0.08); iron follow-on formula in term infants −0.12 (−0.31 to 0.07); and sn-2 palmitate supplemented formula in term infants −0.09 (−0.37 to 0.19). Participants from the nucleotide trial were too young to have sat their General Certificate of Secondary Education (GCSE) examinations at the time of linkage to school data. Secondary outcomes did not differ for nutrient enriched, high iron, sn-2 palmitate, or nucleotide supplemented formulas, but at 11 years, preterm and term participants randomised to LCPUFA supplemented formula scored lower in English and mathematics. Conclusions Evidence from these randomised controlled trials indicated that the infant formula modifications did not promote long term cognitive benefit compared with standard infant formulas.
Supervised learning based on tumor imaging and biopsy transcriptomics predicts response of hepatocellular carcinoma to transarterial chemoembolization
Authors: Tuyana Boldanova, Geoffrey Fucile, Jan Vosshenrich, Aleksei Suslov, Caner Ercan, Mairene Coto-Llerena, Luigi M. Terracciano, Christoph J. Zech, Daniel T. Boll, Stefan Wieland, Markus H. Heim
Journal: Cell Reports Medicine (2021)

Although transarterial chemoembolization (TACE) is the most widely used treatment for intermediate-stage, unresectable hepatocellular carcinoma (HCC), it is only effective in a subset of patients. In this study, we combine clinical, radiological, and genomics data in supervised machine-learning models toward the development of a clinically applicable predictive classifier of response to TACE in HCC patients. Our study consists of a discovery cohort of 33 tumors through which we identify predictive biomarkers, which are confirmed in a validation cohort. We find that radiological assessment of tumor area and several transcriptomic signatures, primarily the expression of FAM111B and HPRT1, are most predictive of response to TACE. Logistic regression decision support models consisting of tumor area and RNA-seq gene expression estimates for FAM111B and HPRT1 yield a predictive accuracy of ∼90%. Reverse transcription droplet digital PCR (RT-ddPCR) confirms these genes in combination with tumor area as a predictive classifier for response to TACE.
Epidemiological Characterization and Determination of <i>TP53</i> and IGHV Mutational Status of a Large Series of Previously-Untreated Chronic Lymphocytic Leukemia (CLL) Patients in Spain: The Epicll Study
Authors: María José Terol, Alicia Serrano, Blanca Ferrer Lores, Francesc Bosch, Marcos Gonzalez Diaz, Marta Crespo, Miguel Alcoceba, Azahara Fuentes, Javier F Chaves, Lucia Esteve, Cristina Loriente, Miguel Villanueva
Journal: Blood (2021)
Melatonin receptor 1A, but not 1B, knockout decreases biliary damage and liver fibrosis during cholestatic liver injury
Authors: Nan Wu, Guido Carpino, Ludovica Ceci, Leonardo Baiocchi, Heather Francis, Lindsey Kennedy, Tianhao Zhou, Lixian Chen, Keisaku Sato, Konstantina Kyritsi, Vik Meadows, Burcin Ekser, Antonio Franchitto, Romina Mancinelli, Paolo Onori, Eugenio Gaudio, Shannon Glaser, Gianfranco Alpini
Journal: Hepatology (2021)

Abstract Background and Aims Melatonin reduces biliary damage and liver fibrosis in cholestatic models by interaction with melatonin receptors 1A (MT1) and 1B (MT2). MT1 and MT2 can form heterodimers and homodimers, but MT1 and MT2 can heterodimerize with the orphan receptor G protein–coupled receptor 50 (GPR50). MT1/GPR50 dimerization blocks melatonin binding, but MT2/GPR50 dimerization does not affect melatonin binding. GPR50 can dimerize with TGFβ receptor type I (TGFβRI) to activate this receptor. We aimed to determine the differential roles of MT1 and MT2 during cholestasis. Approach and Results Wild‐type (WT), MT1 knockout (KO), MT2KO, and MT1/MT2 double KO (DKO) mice underwent sham or bile duct ligation (BDL); these mice were also treated with melatonin. BDL WT and multidrug resistance 2 KO (Mdr2 −/− ) mice received mismatch, MT1, or MT2 Vivo‐Morpholino. Biliary expression of MT1 and GPR50 increases in cholestatic rodents and human primary sclerosing cholangitis (PSC) samples. Loss of MT1 in BDL and Mdr2 −/− mice ameliorated biliary and liver damage, whereas these parameters were enhanced following loss of MT2 and in DKO mice. Interestingly, melatonin treatment alleviated BDL‐induced biliary and liver injury in BDL WT and BDL MT2KO mice but not in BDL MT1KO or BDL DKO mice, demonstrating melatonin’s interaction with MT1. Loss of MT2 or DKO mice exhibited enhanced GPR50/TGFβR1 signaling, which was reduced by loss of MT1. Conclusions Melatonin ameliorates liver phenotypes through MT1, whereas down‐regulation of MT2 promotes liver damage through GPR50/TGFβR1 activation. Blocking GPR50/TGFβR1 binding through modulation of melatonin signaling may be a therapeutic approach for PSC.
Posoleucel (ALVR105), an Off-the-Shelf, Multivirus-Specific T-Cell Therapy, for the Prevention of Viral Infections Post-HCT: Results from an Open-Label Cohort of a Phase 2 Trial
Authors: Sanjeet S Dadwal, Michael Shuster, Gary Douglas Myers, Keith Boundy, Marshelle Warren, Elizabeth Stoner, Thuy Truong, Joshua A. Hill
Journal: Blood (2021)
The Role of Doppler Ultrasound in the Diagnosis of Postnatal Testicular Torsion in Children
Authors: E. B. Olkhova, S. Yu. Borisov, M. V. Topolnik, A. Yu. Tagirova, S. V. Zhumasitov, T. V. Mukaseeva
Journal: Radiology - Practice (2021)

The diagnostic significance of the color Doppler study of testicular blood flow in testicular torsion has been studied for about 40 years, however, the prognostic value of the results obtained is ambiguous, as are the actual imaging capabilities of the technique. Our own experience of 110 observations of testicular torsion in children older than the neonatal period allows us to draw statistically reliable conclusions. Made on equipment premium-class research made it possible to evaluate how visualization intratesticular vascular pattern, and whirpool-sign and submit the primitive model of the actual inversion, explaining the impossibility of rendering whirpool-sign with the greatest tight inversion. The dynamics of testicular blood flow was studied immediately after successful and unsuccessful manual detorsion and in the long term after operative detorsion and orchopexy. The publication contains a brief analysis of the literature and is extensively illustrated.
Increased Frequency of Mutations in the Gene Responsible for Familial Mediterranean Fever (<i>MEFV</i>) in a Cohort of Patients with Chronic Idiopathic Neutropenia
Authors: Panagiotis Skendros, Irene Mavroudi, Stavros Papadakis, Peggy Kanellou, Erasmia Boutakoglou, Grigorios Tsaknakis, Charalampos Pontikoglou, George Goulielmos, Konstantinos Ritis, Helen A. Papadaki
Journal: Blood (2021)
Surgical data science – from concepts toward clinical translation
Authors: Lena Maier-Hein, Matthias Eisenmann, Duygu Sarikaya, Keno März, Toby Collins, Anand Malpani, Johannes Fallert, Hubertus Feussner, Stamatia Giannarou, Pietro Mascagni, Hirenkumar Nakawala, Adrian Park, Carla Pugh, Danail Stoyanov, Swaroop S. Vedula, Kevin Cleary, Gabor Fichtinger, Germain Forestier, Bernard Gibaud, Teodor Grantcharov, Makoto Hashizume, Doreen Heckmann-Nötzel, Hannes G. Kenngott, Ron Kikinis, Lars Mündermann, Nassir Navab, Sinan Onogur, Tobias Roß, Raphael Sznitman, Russell H. Taylor, Minu D. Tizabi, Martin Wagner, Gregory D. Hager, Thomas Neumuth, Nicolas Padoy, Justin Collins, Ines Gockel, Jan Goedeke, Daniel A. Hashimoto, Luc Joyeux, Kyle Lam, Daniel R. Leff, Amin Madani, Hani J. Marcus, Ozanan Meireles, Alexander Seitel, Dogu Teber, Frank Ückert, Beat P. Müller-Stich, Pierre Jannin, Stefanie Speidel
Journal: Medical Image Analysis (2021)

Recent developments in data science in general and machine learning in particular have transformed the way experts envision the future of surgery. Surgical Data Science (SDS) is a new research field that aims to improve the quality of interventional healthcare through the capture, organization, analysis and modeling of data. While an increasing number of data-driven approaches and clinical applications have been studied in the fields of radiological and clinical data science, translational success stories are still lacking in surgery. In this publication, we shed light on the underlying reasons and provide a roadmap for future advances in the field. Based on an international workshop involving leading researchers in the field of SDS, we review current practice, key achievements and initiatives as well as available standards and tools for a number of topics relevant to the field, namely (1) infrastructure for data acquisition, storage and access in the presence of regulatory constraints, (2) data annotation and sharing and (3) data analytics. We further complement this technical perspective with (4) a review of currently available SDS products and the translational progress from academia and (5) a roadmap for faster clinical translation and exploitation of the full potential of SDS, based on an international multi-round Delphi process.
Therapeutic Targeting of Mertk and BCL-2 in T-Cell and Early T-Precursor Acute Lymphoblastic Leukemia
Authors: Ryan J Summers, Juhi Jain, Eleana Vasileiadi, Brittany Smith, Madison Stout, James Kelvin, Xiaodong Wang, Stephen V Frye, H. Shelton Earp, Jeffrey W. Tyner, Erik Dreaden, Deborah DeRyckere, Douglas K Graham
Journal: Blood (2021)
Alternate-Day Dosing of Caplacizumab for Immune-Mediated Thrombotic Thrombocytopenic Purpura
Authors: Lucas Kühne, Dennis A. Eichenauer, Paul Knöbl, Linus A. Völker, Jessica Kaufeld, Ralph Wendt, Holger Hägele, Thomas Osterholt, Marcus Bieringer, Veronika Buxhofer-Ausch, Jan Menne, Ulf Schoenermarck, Paul Brinkkoetter
Journal: Blood (2021)
Improved Overall Survival of Patients Treated with Abatacept in Combination with a Calcineurin Inhibitor and Methotrexate Following 7/8 HLA-Matched Unrelated Allogeneic Hematopoietic Stem Cell Transplantation: Analysis of the Center for International Blood and Marrow Transplant Research Database
Authors: Leslie S Kean, Linda J Burns, Tzuyung Douglas Kou, Roxanne Kapikian, Xiao-Ying Tang, Mei-Jie Zhang, Michael Hemmer, Sean E Connolly, Martin Polinsky, Brian Gavin, Andres Gomez, Marcelo C Pasquini
Journal: Blood (2021)
Absence of Hyperactivation of Fibrinolysis Explains the Lack of Hemostatic Efficacy of Prophylactic Tranexamic Acid (TXA) in Hypoproliferative Thrombocytopenia
Authors: Anton Ilich, Terry B. Gernsheimer, Darrell J Triulzi, Heather Herren, Siobhan P Brown, Lori A Holle, Andrew T Lucas, Nahed El Kassar, Alisa S. Wolberg, Susanne May, Nigel S Key
Journal: Blood (2021)
Manufacture and Immunological Characterization of GMP-Compliant Functional Sars-COV-2 Cytotoxic T Lymphocytes (CTLs) Utilizing the Clinimacs ® Cytokine Capture System
Authors: Yaya Chu, Jordan Milner, Margaret Lamb, Elena Maryamchik, Olivia Rigot, Janet Ayello, Lauren Harrison, Rosemarie Shaw, Greg K. Behbehani, Elaine R. Mardis, Katherine E Miller, Lakshmi Prakruthi Rao Venkata, Hsiaochi Chang, Dean Anthony Lee, Elana Y. Rosenthal, Stephan Kadauke, Nancy Bunin, Julie-An Talano, Bryon Johnson, Yongping Wang, Mitchell S. Cairo
Journal: Blood (2021)
Phase 1 Dose Escalation and Cohort Expansion Study of the Anti-ROR1 Antibody-Drug Conjugate Zilovertamab Vedotin (MK-2140) for the Treatment of Non-Hodgkin Lymphoma
Authors: Michael Wang, Matthew Mei, Paul M. Barr, Jacqueline Barrientos, Sven de Vos, Richard Furman, Krish Patel, Philip A. Thompson, Michael Choi, Avyakta Kallam, Ying Zhu, Samhita Chakraborty, Patricia Marinello, Stephen E. Spurgeon
Journal: Blood (2021)
Cybord-Dara in Newly Diagnosed Transplant-Eligible Multiple Myeloma: Follow up Results from the 16-Bcni-001/Ctrial-IE 16-02 Study Show High Rates of MRD Negativity at End of Treatment
Authors: Dawn Swan, Michael E. O'Dwyer, Mary Cahill, Janusz Krawczyk, Vitaliy Mykytiv, John Quinn, Robert Henderson, Cian McEllistrim, Andres Hernando, Imelda Parker, Marc Nolan, Elizabeth Lenihan, Eva Szegezdi, Serika D Naicker, Kevin Lynch, Alessandro Natoni, Aideen Ryan, Philip Murphy
Journal: Blood (2021)
Association between CYP3A4, CYP3A5, and ABCB1 Genotype, Tacrolimus Concentrations, and Outcomes Among Allogeneic Hematopoietic Stem Cell Transplantation Patients
Authors: Teresa Ho, Janelle Perkins, Rebecca Gonzalez, J Kevin Hicks, Taiga Nishihori, Nelli Bejanyan, Joseph Pidala, Hany Elmariah
Journal: Blood (2021)
fMRI derived visual field measures correlate highly with clinical perimetry assessments in choroideremia patients
Authors: Tomas S. Aleman, Ed H. Silson, Aimee Willett, Leona W. Serrano, Denise J. Pearson, Andreas M. Rauschecker, Albert M. Maguire, Chris I. Baker, Jean Bennett, Manzar Ashtari
Journal: Molecular Therapy (2018)