tbuckley/cabot-search huggingface dataset:
TEMPORAL TRENDS IN THE USE OF INTRAVASCULAR IMAGING ASSESSMENT DURING CORONARY ANGIOGRAPHY AT A QUATERNARY-CARE CENTER IN THE UNITED STATES
Authors: Shawn Gogia, Madison Edens, Khady Fall, Denizhan Ozdemir, Hussein Rahim, Amisha Patel, Dimitrios Karmpaliotis, Ajay Kirtane, Ori Ben-Yehuda, Bjorn Redfors, Martin Leon, Mitsuaki Matsumura, Akiko Maehara, Gary Mintz, Ziad Ali
Journal: Journal of the American College of Cardiology (2021)
THE IMPACT OF CORONARY REVASCULARIZATION ON REGIONAL VESSEL-SPECIFIC CORONARY FLOW CAPACITY: A SERIAL [15O]H2O POSITRON EMISSION TOMOGRAPHY PERFUSION IMAGING STUDY
Authors: Ruben Willem De Winter, Ruurt Jukema, Pepijn Van Diemen, Stefan Schumacher, Roel Driessen, Wijnand Stuijfzand, Michiel Bom, Henk Everaars, Albert van Rossum, Peter van de Ven, Niels Verouden, Alexander Nap, Ibrahim Danad, Pieter Raijmakers, Paul Knaapen
Journal: Journal of the American College of Cardiology (2021)
Overcoming challenges of HERG potassium channel liability through rational design: Eag1 inhibitors for cancer treatment
Authors: Žan Toplak, Louise A. Hendrickx, Reham Abdelaziz, Xiaoyi Shi, Steve Peigneur, Tihomir Tomašič, Jan Tytgat, Lucija Peterlin‐Mašič, Luis A. Pardo
Journal: Medicinal Research Reviews (2021)

Abstract Two decades of research have proven the relevance of ion channel expression for tumor progression in virtually every indication, and it has become clear that inhibition of specific ion channels will eventually become part of the oncology therapeutic arsenal. However, ion channels play relevant roles in all aspects of physiology, and specificity for the tumor tissue remains a challenge to avoid undesired effects. Eag1 (K V 10.1) is a voltage‐gated potassium channel whose expression is very restricted in healthy tissues outside of the brain, while it is overexpressed in 70% of human tumors. Inhibition of Eag1 reduces tumor growth, but the search for potent inhibitors for tumor therapy suffers from the structural similarities with the cardiac HERG channel, a major off‐target. Existing inhibitors show low specificity between the two channels, and screenings for Eag1 binders are prone to enrichment in compounds that also bind HERG. Rational drug design requires knowledge of the structure of the target and the understanding of structure–function relationships. Recent studies have shown subtle structural differences between Eag1 and HERG channels with profound functional impact. Thus, although both targets' structure is likely too similar to identify leads that exclusively bind to one of the channels, the structural information combined with the new knowledge of the functional relevance of particular residues or areas suggests the possibility of selective targeting of Eag1 in cancer therapies. Further development of selective Eag1 inhibitors can lead to first‐in‐class compounds for the treatment of different cancers.
SYSTEMIC REVIEW AND META-ANALYSIS OF VITAMIN K ANTAGONIST VS DIRECT ORAL ANTICOAGULANTS FOR TREATMENT OF LEFT VENTRICULAR THROMBUS
Authors: Saqer Alkharabsheh, Mohamed Khayata, Ben Alencherry, Muzna Hussain, Scott Cameron, Marcelo Gomes, Patrick Collier
Journal: Journal of the American College of Cardiology (2021)
Identifying urban hotspots of dengue, chikungunya, and Zika transmission in Mexico to support risk stratification efforts: a spatial analysis
Authors: Felipe Dzul-Manzanilla, Fabián Correa-Morales, Azael Che-Mendoza, Jorge Palacio-Vargas, Gustavo Sánchez-Tejeda, Jesus F González-Roldan, Hugo López-Gatell, Adriana E Flores-Suárez, Hector Gómez-Dantes, Giovanini E Coelho, Haroldo S da Silva Bezerra, Norma Pavia-Ruz, Audrey Lenhart, Pablo Manrique-Saide, Gonzalo M Vazquez-Prokopec
Journal: The Lancet Planetary Health (2021)
Abstract 20672: Panoramic Optical Mapping Reveals a Cascade of Accelerating Rotors Across the Entire Atria During Initiation and Early Stabilization of Atrial Fibrillation
Authors: Oscar Salvador Montanes, Rafael J Ramirez, Yoshio Takemoto, Steven R Ennis, Daniel Garcia Iglesias, Sicong Wang, Jiang Jiang, Sergey Mironov, Sandeep Pandit, Jose Jalife, Omer Berenfeld
Journal: Circulation (2017)

Background: Wave propagation during early atrial fibrillation (AF) is poorly understood partially due to inadequate mapping techniques. We developed a new optical approach enabling endocardial pano...
A systematic review of biological, social and environmental factors associated with epigenetic clock acceleration
Authors: Lara Oblak, Jeroen van der Zaag, Albert T. Higgins-Chen, Morgan E. Levine, Marco P. Boks
Journal: Ageing Research Reviews (2021)

Aging involves a diverse set of biological changes accumulating over time that leads to increased risk of morbidity and mortality. Epigenetic clocks are now widely used to quantify biological aging, in order to investigate determinants that modify the rate of aging and to predict age-related outcomes. Numerous biological, social and environmental factors have been investigated for their relationship to epigenetic clock acceleration and deceleration. The aim of this review was to synthesize general trends concerning the associations between human epigenetic clocks and these investigated factors. We conducted a systematic review of all available literature and included 156 publications across 4 resource databases. We compiled a list of all presently existing blood-based epigenetic clocks. Subsequently, we created an extensive dataset of over 1300 study findings in which epigenetic clocks were utilized in blood tissue of human subjects to assess the relationship between these clocks and numeral environmental exposures and human traits. Statistical analysis was possible on 57 such relationships, measured across 4 different epigenetic clocks (Hannum, Horvath, Levine and GrimAge). We found that the Horvath, Hannum, Levine and GrimAge epigenetic clocks tend to agree in direction of effects, but vary in size. Body mass index, HIV infection, and male sex were significantly associated with acceleration of one or more epigenetic clocks. Acceleration of epigenetic clocks was also significantly related to mortality, cardiovascular disease, cancer and diabetes. Our findings provide a graphical and numerical synopsis of the past decade of epigenetic age estimation research and indicate areas where further attention could be focused in the coming years.
CLINICAL UTILITY OF MECHANICAL ECHOCARDIOGRAPHIC DISPERSION TO ASSESS LEFT VENTRICULAR FUNCTION AND ISCHEMIA OR INFARCTION DETECTED BY GATED 99M-TC SESTAMIBI-SPECT
Authors: Nilda Espinola-Zavaleta, Neftali E. Antonio-Villa, Ricardo Alvarez-Santana, Erick Alexanderson-Rosas
Journal: Journal of the American College of Cardiology (2021)
Long Noncoding RNA CTD-2245E15.3 Promotes Anabolic Enzymes ACC1 and PC to Support Non–Small Cell Lung Cancer Growth
Authors: Chen Wang, Xiangfeng Meng, Yu Zhou, Jing Yu, Qing Li, Zhicong Liao, Yuanyuan Gu, Jiayi Han, Shuo Linghu, Zichen Jiao, Tao Wang, Chen-Yu Zhang, Xi Chen
Journal: Cancer Research (2021)

Abstract Long noncoding RNAs (lncRNA) have been shown to play critical regulatory roles in the onset and progression of human cancers. However, the functions of a large proportion of lncRNAs are still unexplored. Here we describe a novel lncRNA, CTD-2245E15.3, that promotes lung tumorigenesis by regulating the anabolic enzymes acetyl-CoA carboxylase 1 (ACC1, encoded by the ACACA gene) and pyruvate carboxylase (PC). Differentially expressed lncRNAs between non–small cell lung cancer (NSCLC) and paired adjacent nontumor tissues were identified by a microarray and validated using quantitative real-time polymerase chain reaction. CTD-2245E15.3 was significantly upregulated in NSCLC and was mainly located in the cytoplasm. Knockdown of CTD-2245E15.3 by specific antisense oligonucleotides suppressed cell growth in vitro and in vivo, largely due to cell-cycle arrest and induction of apoptosis. Overexpression of CTD-2245E15.3 in an orthotopic model of lung cancer led to a significant increase in total tumor burden. CTD-2245E15.3 exerted its oncogenic function by binding ACC1 and PC, which are key anabolic factors for biomolecule synthesis in rapidly proliferating tumor cells. Knockdown of CTD-2245E15.3 increased phosphorylation of ACC1 at an inhibitory site for enzymatic activity and promoted PC degradation via ubiquitination. Supplements of palmitate or oxaloacetate, products of ACC1 and PC, alleviated the suppression of cell growth caused by loss of CTD-2245E15.3. These findings reveal the important role of CTD-2245E15.3 as an oncogenic lncRNA in the anabolic process for tumor growth. Significance: These findings demonstrate a novel lncRNA CTD-2245E15.3 that binds and positively regulates anabolic enzymes ACC1 and PC to promote tumor growth.
Dysregulation of the Lysophosphatidylcholine/Autotaxin/Lysophosphatidic Acid Axis in Acute‐on‐Chronic Liver Failure Is Associated With Mortality and Systemic Inflammation by Lysophosphatidic Acid–Dependent Monocyte Activation
Authors: Francesca M. Trovato, Rabiya Zia, Salvatore Napoli, Kate Wolfer, Xiaohong Huang, Phillip E. Morgan, Hannah Husbyn, Marwa Elgosbi, Manuele Lucangeli, Rosa Miquel, Ian Wilson, Nigel David Heaton, Michael A. Heneghan, Georg Auzinger, Charalambos G. Antoniades, Julia A. Wendon, Vishal C. Patel, Muireann Coen, Evangelos Triantafyllou, Mark J. McPhail
Journal: Hepatology (2021)

Background &amp; Aims Acute‐on‐chronic liver failure (ACLF) is characterized by systemic inflammation, monocyte dysfunction, and susceptibility to infection. Lysophosphatidylcholines (LPCs) are immune‐active lipids whose metabolic regulation and effect on monocyte function in ACLF is open for study. Approaches &amp; Results Three hundred forty‐two subjects were recruited and characterized for blood lipid, cytokines, phospholipase (PLA), and autotaxin (ATX) concentration. Peripheral blood mononuclear cells and CD14 + monocytes were cultured with LPC, or its autotaxin (ATX)‐derived product, lysophosphatidic acid (LPA), with or without lipopolysaccharide stimulation and assessed for surface marker phenotype, cytokines production, ATX and LPA‐receptor expression, and phagocytosis. Hepatic ATX expression was determined by immunohistochemistry. Healthy volunteers and patients with sepsis or acute liver failure served as controls. ACLF serum was depleted in LPCs with up‐regulated LPA levels. Patients who died had lower LPC levels than survivors (area under the receiver operating characteristic curve, 0.94; P &lt; 0.001). Patients with high‐grade ACLF had the lowest LPC concentrations and these rose over the first 3 days of admission. ATX concentrations were higher in patients with AD and ACLF and correlated with Model for End‐Stage Liver Disease, Consortium on Chronic Liver Failure–Sequential Organ Failure Assessment, and LPC/LPA concentrations. Reduction in LPC correlated with higher monocyte Mer‐tyrosine‐kinase (MerTK) and CD163 expression. Plasma ATX concentrations rose dynamically during ACLF evolution, correlating with IL‐6 and TNF‐α, and were associated with increased hepatocyte ATX expression. ACLF patients had lower human leukocyte antigen‐DR isotype and higher CD163/MerTK monocyte expression than controls; both CD163/MerTK expression levels were reduced in ACLF ex vivo following LPA, but not LPC, treatment. LPA induced up‐regulation of proinflammatory cytokines by CD14 + cells without increasing phagocytic capacity. Conclusions ATX up‐regulation in ACLF promotes LPA production from LPC. LPA suppresses MerTK/CD163 expression and increases monocyte proinflammatory cytokine production. This metabolic pathway could be investigated to therapeutically reprogram monocytes in ACLF.
IS AN INITIAL ATRIAL FIBRILLATION EPISODE ONE AND DONE? A PROSPECTIVE IMPLANTABLE LOOP RECORDER ANALYSIS
Authors: Avni H. Thakore, James Nguyen, Simcha Pollack, Evan Shlofmitz, Winifred Mei, Vinod Jayam, William Shin, Joshua Stern, David Hoch, Joseph Levine
Journal: Journal of the American College of Cardiology (2021)
Abstract 16077: Biventricular Takotsubo Cardiomyopathy as the Initial Manifestation of a Pheochromocytoma
Authors: Azucena Martinez Caballero, Sebastian Gallo-Bernal, Nicolas Isaza, Daniel Isaza, Claudia Jaimes
Journal: Circulation (2019)

A previously healthy 21-year-old woman presented to an outside hospital emergency room complaining of acute chest pain, diaphoresis and shortness of breath. ECG showed sinus tachycardia and diffuse...
Hypopigmented atrophic plaques in a young woman
Authors: Prateek Sharma, V Ramesh
Journal: BMJ (2021)

A woman in her 20s presented to dermatology clinic with a four year history of a mildly itchy hypopigmented patch in her natal cleft, and similar itchy lesions that had gradually appeared on the back of both knees over the past six months (fig 1, fig 2). The lesions ranged from white to brown. 



Fig 1 
Hypopigmented atrophic plaques in upper part of natal cleft





Fig 2 
Hypopigmented atrophic plaques in popliteal fossae



Treatment with topical antifungal creams for suspected candidal intertrigo was unsuccessful.

Cutaneous examination revealed multiple ill defined hypopigmented plaques in the upper part of the natal cleft and both popliteal fossae. On close inspection, the affected skin showed fine wrinkling and increased translucency (not clear in the figure) …
THE GERIATRIC NUTRITIONAL RISK INDEX PREDICTS THE PROGNOSIS IN PATIENTS WITH CHRONIC LIMB-THREATENING ISCHEMIA
Authors: Kuniyasu Ikeoka, Jun Li, Shilpkumar Arora, Tarek Hammad, Stephen Kimura, Siddartha Dash, Mehdi Shishehbor
Journal: Journal of the American College of Cardiology (2021)
Abstract 16015: A Rare Cutaneous Adverse Drug Reaction With Apixaban
Authors: Khezar Syed, Haseeb Chaudhary, Tayyab Ali Waheed, Ansar Aziz
Journal: Circulation (2020)

We report a case of apixaban-induced macular rash noticed 3 days after its initiation for atrial fibrillation. Patient denied any fever, arthralgias, myalgias or photosensitivity otherwise. On presentation, she complained of generalized pruritus with a bilateral non-blanchable macular rash on distal lower extremities and dorsum of feet. The labs showed normal cell counts, an elevated serum creatinine of 2.29mg/dl with a bland urine on microscopy. Apixaban was switched to LMWH. Serum creatinine returned to baseline with fluid therapy within 24 hours. Patient was re-challenged with apixaban that caused recurrence of generalized pruritus. It was treated successfully with diphenhydramine and prednisone. She was restarted on LMWH and rash disappeared after 3 days of stopping apixaban. She was later commenced on rivaroxaban without any complications. Several cutaneous adverse drug reactions (cADR) have been reported with direct acting oral anticoagulants (DOAC) like rivaroxaban and edoxaban but are extremely rare with apixaban. The overall reported incidence of dermatologic immune reactions with FXa inhibitors is &lt;0.1%. Previously reported skin eruptions from apixaban include palmoplantar psoriasiform rash, leucocytoclastic vasculitis and acute generalized erythematous pustulosis. Our patient’s Naranjo scale was 7 and her rash improved after cessation of apixaban. The case illustrates a hypersensitivity reaction from apixaban that did not have cross-reactivity with other FXa inhibitors. Early recognition of cADR from this widely used DOAC can avoid potential complications. Minor reactions may be managed by switching to different DOAC therapy. Whether a cross-reactivity truly exists must be explored by validated skin testing.
Data Leak Exposes Early COVID-19 Vaccine Manufacturing Hiccups: The Journal of the American Medical Association
Authors: Jennifer Abbasi
Journal: JAMA (2021)

After a cyberattack late last year against the European Medicines Agency (EMA), anonymous emails dispatched a trove of classified documents to academics and journalists  In a Jan 25 statement, the EMA said some of the hacked documents--which mainly concerned COVID-19 medicines and vaccines--were altered in a way that could undermine trust in vaccines  According to The BMJ's recent news investigation, the documents revealed that regulators reviewing vaccine candidates had concerns about truncated messenger RNA (mRNA) in early batches of Pfizer-BioNTech's COVID-19 vaccine  These early batches developed for commercial production had about 55% intact mRNA, a lower percentage than in clinical trial batches, with uncertain implications
Optogenetic activation of local colonic sympathetic innervations attenuates colitis by limiting immune cell extravasation
Authors: Maya Schiller, Hilla Azulay-Debby, Nadia Boshnak, Yehezqel Elyahu, Ben Korin, Tamar L. Ben-Shaanan, Tamar Koren, Maria Krot, Fahed Hakim, Asya Rolls
Journal: Immunity (2021)

The sympathetic nervous system is composed of an endocrine arm, regulating blood adrenaline and noradrenaline, and a local arm, a network of fibers innervating immune organs. Here, we investigated the impact of the local arm of the SNS in an inflammatory response in the colon. Intra-rectal insertion of an optogenetic probe in mice engineered to express channelrhodopsin-2 in tyrosine hydroxylase cells activated colonic sympathetic fibers. In contrast to systemic application of noradrenaline, local activation of sympathetic fibers attenuated experimental colitis and reduced immune cell abundance. Gene expression profiling showed decreased endothelial expression of the adhesion molecule MAdCAM-1 upon optogenetic stimulation; this decrease was sensitive to adrenergic blockers and 6-hydroxydopamine. Antibody blockade of MAdCAM-1 abrogated the optogenetic effect on immune cell extravasation into the colon and the pathology. Thus, sympathetic fibers control colonic inflammation by regulating immune cell extravasation from circulation, a mechanism likely relevant in multiple organs.
Covid-19: Heavy use of oxygen brings new danger to world’s hospitals
Authors: Owen Dyer
Journal: BMJ (2021)

A week marked by deadly hospital fires and a mass asphyxiation of covid-19 patients has highlighted the risks inherent to that inevitable accompaniment of a respiratory pandemic-vastly increased oxygen use.A total of 82 people were left dead and 110 injured from a hospital fire on 24 April in Baghdad, Iraq, which began with an explosion caused by "a fault in the storage of oxygen cylinders," hospital sources told Agence France-Presse.
DIFFERENCES IN BASELINE DEMOGRAPHICS AND CLINICAL OUTCOMES BETWEEN MEN AND WOMEN WITH SPONTANEOUS CORONARY ARTERY DISSECTION
Authors: Cameron McAlister, Mesfer Alfadhel, Rohit Samuel, Andrew Starovoytov, Johandra Argote Parolis, Tejana Grewal, Eve Aymong, Jacqueline Saw
Journal: Journal of the American College of Cardiology (2021)
TRENDS AND PREDICTORS OF MORTALITY IN PATIENTS ON VENO-ARTERIAL EXTRACORPOREAL MEMBRANE OXYGENATION(VA ECMO) FOR CARDIOGENIC SHOCK
Authors: Moinuddin Syed, Muhammad Khan, Pratik Agrawal, Mohammed Osman, Salman Zahid, Sudarshan Balla
Journal: Journal of the American College of Cardiology (2021)
Covid-19: Biden aims for 70% of Americans to have at least one vaccination by 4 July
Authors: Janice Hopkins Tanne
Journal: BMJ (2021)

President Joe Biden has said that he wants 70% of people in the US to have received at least one dose of a covid-19 vaccine by 4 July, the Independence Day holiday popular for family gatherings. 1 Many states plan to reopen their economies completely in the next few weeks.
FEASIBILITY OF POINT OF CARE CARDIAC ULTRASOUND PERFORMED AT RURAL HEALTH CENTERS IN TANZANIA
Authors: Richard Bayer, Deliliah Kimambo, Samuel Kennedy, Engerasiya Kifai, Neema Kailembo, Christie Eichberg, Sarah Markosky, Ishan Shah, Eric Powers, Peter Zwerner, Susan Dorman, Mohamed Janabi
Journal: Journal of the American College of Cardiology (2021)
Appropriateness of Parenteral Antibiotic Treatment for Patients with Presumed Lyme Disease
Authors: American College of Rheumatology the Council of the Infectious Diseases Society of America.
Journal: Annals of Internal Medicine (1993)

Position Papers15 September 1993Appropriateness of Parenteral Antibiotic Treatment for Patients with Presumed Lyme DiseaseAmerican College of Rheumatology the Council of the Infectious Diseases Society of America.American College of Rheumatology the Council of the Infectious Diseases Society of America.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-119-6-199309150-00012 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail This Position Paper accompanies a Review paper in this issue (Empirical Parenteral Antibiotic Treatment of Patients with Fibromyalgia and Fatigue and a Positive Serologic Result for Lyme Disease: A Cost-Effectiveness Analysis); see pages 503-509.Position StatementGrowing attention to Lyme disease in the medical and lay press has led to increased serologic testing in patients with nonspecific symptoms (such as myalgia and chronic fatigue) without a history of classical clinical features of Lyme disease. Many patients with such nonspecific symptoms and a positive serologic test result are assumed to have Lyme disease and have been treated empirically with prolonged antibiotic ...REFERENCE1. Lightfoot RW Jr, Luft BJ, Rahn DW, Steere AC, Sigal LH, Zoschke DC, et al. Empiric parenteral antibiotic treatment of patients with fibromyalgia/fatigue and a positive serologic result for Lyme disease. A cost-effectiveness analysis. Ann Intern Med. 1993; 119:503-9. Google Scholar Author, Article, and Disclosure InformationAffiliations: A Joint Statement of The American College of Rheumatology and the Council of The Infectious Diseases Society of America** This paper was written by Benjamin J. Luft, MD; Pierce Gardner, MD; and Robert W. Lightfoot, Jr., MD. Members of the joint committee from the American College of Rheumatology and the Infectious Diseases Society of America included Melvin C. Britton, MD; Pierce Gardner, MD; Ronald L. Kaufman, MD; Robert W. Lightfoot, Jr., MD; Benjamin J. Luft, MD; Daniel W. Rahn, MD; Leonard H. Sigal, MD; Allen C. Steere, MD; David C. Zoschke, MD. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byChronic Lyme Disease: A Survey of Connecticut Primary Care PhysiciansBorrelia Burgdorferi (Lyme Disease)Death from Inappropriate Therapy for Lyme DiseaseLyme Arthritis 15 September 1993Volume 119, Issue 6Page: 518KeywordsAntibioticsEnzyme linked immunosorbent assayFatigueFibromyalgiaInfectious diseasesLyme diseaseMyalgiaPatientsSpecificityToxicity Issue Published: 15 September 1993 Copyright & PermissionsCopyright © 1993 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Thoracic aortic aneurysms: expanding the potential cardiovascular consequences of obstructive sleep apnoea
Authors: Luciano F. Drager, Miguel A. Martinez-Garcia
Journal: European Respiratory Journal (2021)

<b>This editorial highlights recent evidence suggesting that a common sleep-related breathing disorder, namely obstructive sleep apnoea, may contribute to thoracic aneurism expansion independent from traditional risk factors</b>https://bit.ly/38nxKBY
INCIDENTAL AORTO-LEFT ATRIAL APPENDAGE FISTULA COMPLICATING A WATCHMAN PROCEDURE
Authors: Blair Warren, Aakash Patel, Rony Shah, Thomas Noel, Marilyn Cox, Suman Pasupuleti, Jeffrey Jordan, Oyesanmi Olugbenga, Dudith Pierre-Victor, Farhat Khairallah
Journal: Journal of the American College of Cardiology (2021)
Individualized Nutritional Support for Hospitalized Patients With Chronic Heart Failure
Authors: Lara Hersberger, Anna Dietz, Helene Bürgler, Annika Bargetzi, Laura Bargetzi, Nina Kägi-Braun, Pascal Tribolet, Filomena Gomes, Claus Hoess, Vojtech Pavlicek, Stefan Bilz, Sarah Sigrist, Michael Brändle, Christoph Henzen, Robert Thomann, Jonas Rutishauser, Drahomir Aujesky, Nicolas Rodondi, Jacques Donzé, Zeno Stanga, Beat Mueller, Philipp Schuetz
Journal: Journal of the American College of Cardiology (2021)
MITRAL ANNULAR DYNAMICS IN ATRIAL FIBRILLATION VERSUS SINUS RHYTHM - NOVEL INSIGHTS INTO THE MECHANISM OF ATRIAL FUNCTIONAL MITRAL REGURGITATION
Authors: Sébastien Deferm, Philippe Bertrand, David Verhaert, Frederik Verbrugge, Jeroen Dauw, Liesbeth Bruckers, Filip Rega, James Thomas, Robert Levine, Pieter Vandervoort
Journal: Journal of the American College of Cardiology (2021)