tbuckley/cabot-search huggingface dataset:
Rucksack Paralysis
Authors: Jasper R. Daube
Journal: JAMA (1969)

Seventeen patients suffered damage to the upper trunk of the brachial plexus as a result of wearing a heavy backpack, or rucksack. Impairment was predominantly motor and sensory on the left side with minimal pain. The patients were normal, healthy young men, except two who had underlying bony deformities. Disability was often severe and recovery prolonged. Improved rucksack design, limits on the amount of weight carried in the rucksack, and medical and paramedical personnel familiar with the disorder could reduce the frequency and severity of this injury.
Trial in Progress: The Phase III, Randomized, Open-Label, Multicenter COMMODORE 1 Study Evaluating the Efficacy and Safety of Crovalimab Versus Eculizumab in Adult and Adolescent Patients with Paroxysmal Nocturnal Hemoglobinuria Currently Treated with Complement Inhibitors
Authors: Antonio Risitano, Alexander Röth, Austin Kulasekararaj, Jeffrey Pu, Jun-ichi Nishimura, Lilyan Wright, Anita Appius, Alexandre Sostelly, Sasha Sreckovic, Charlotte Vignal, Talha Munir
Journal: Blood (2020)
Tuberculosis
Authors: Thomas L. Petty
Journal: JAMA (1996)

Tuberculosis Today, more people have tuberculosis than at the time of the initiation of effective chemotherapy in the mid-1940s, when streptomycin and PAS (para-aminosalicylic acid) were introduced, followed by the miracle drug isoniazid. These drugs, when given in combination for a sufficient time, could cure virtually every person with active tuberculosis of any type. But, alas, drug resistance emerged, and efforts directed toward the global control of tuberculosis were feeble and therefore futile. Today it is estimated that approximately one third of the world's population is infected. So, although we have accumulated great knowledge about etiology, pathogenesis, and treatment, we have failed in our goal of the control of tuberculosis, for a number of bureaucratic and economic reasons. The authors of<i>Tuberculosis</i>have produced a magnificent and comprehensive, full-length text, covering virtually everything that we now know about tuberculosis. Its seven sections range from history to clinical manifestations to prevention
Addiction Medicine
Authors: Richard Frances
Journal: JAMA (1992)

Addiction psychiatry achieved formal recognition as a subspecialty this year with the American Board of Medical Specialists approval of a certification process, including fellowships and an examination for added qualifications in addiction psychiatry through the American Board of Psychiatry and Neurology. The first examination for subspecialty certification will occur in April 1993. Psychiatry is taking a leading role in recognizing the growing complexity of addiction medicine. Recently, the Group for the Advancement of Psychiatry Committee on Alcoholism and Addictions published a position report describing the role of the psychiatrist in the evaluation and treatment of patients with substance use disorders.<sup>1</sup>In addition, there is growing support for other medical specialties to develop American Board of Medical Specialists credentials in addiction medicine. Guidelines for postgraduate training in addiction medicine have been developed, and in 1991, there were 48 postresidency addiction fellowship programs, with 161 graduates and 122 fellows in training.
Decrease in AIDS-Related Mortality in a State Correctional System--New York, 1995-1998
Journal: JAMA (1999)

The New York State Department of Correctional Services (NYSDOCS) administers one of the largest prison systems in the United States, with a population of approximately 70,000 inmates; in 1995, blinded seroprevalence studies indicated that an estimated 9500 inmates were infected with human immunodeficiency virus (HIV). This report summarizes an analysis of death records of inmates, which indicate a substantial reduction in the acquired immunodeficiency syndrome (AIDS)-related deaths from 1995 through 1998 and describes the programs that may have contributed to this decline.
JFK's Assassination
Authors: Robert R. Artwohl
Journal: JAMA (1993)

The Journalinterviews with Humes and Boswell,<sup>1</sup>the Dallas physicians,<sup>2</sup>and Finck<sup>3</sup>cleared up many of the events surrounding the attempted resuscitation and subsequent autopsy of President Kennedy. However, correspondence toThe Journalindicates many physicians are still sympathetic to a key proconspiracy tenet regarding the Kennedy assassination: that the autopsy physicians conspired with the military, the Central Intelligence Agency (CIA), the Federal Bureau of Investigation (FBI), the Secret Service, and other agencies of government to disguise and suppress medical evidence that would show President Kennedy was publicly executed in Dealey Plaza on November 22,1963, by multiple gunmen. Unfortunately, many of the arguments raised in the letters supporting such a complex conspiracy went unanswered. These arguments should be addressed in<i>JAMA</i>for several reasons. See also pp 1507, 1544 and 1552. First, for many physicians, the only contact they will have with arguments for and against conspiracy
Questions and Answers
Journal: JAMA (1967)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Medical Education, Registration and Hospital Service
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Methods of Organic Analysis.
Journal: JAMA (1913)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Endoscopic submucosal dissection of a large cecal polyp involving the ileocecal valve and the terminal ileum
Authors: Georgios Mavrogenis, Fateh Bazerbachi, Dimitrios Mpalomenos, Ioannis Tsevgas, Dimitrios Zachariadis
Journal: Endoscopy (2022)

An 83-year-old man with no significant medical history was referred for endoscopic submucosal dissection (ESD) of a large cecal polyp involving the ileocecal valve and the terminal ileum ([Fig. 1 a]). The strategy of dissection included the creation of a flap at the ileal side, clip and band countertraction [1], and creation of a pocket [2] ([Video 1]). The lesion was lifted with a mixture of hydroxyethyl starch and indigo carmine. An initial incision was performed inside the terminal ileum with a DualKnife 1.5 mm (Olympus, Japan) ([Fig. 1 b]). The presence of fat in this area slowed down the dissection speed and obscured visibility. Progressively a flap was created underneath the lesion. Countertraction was applied using clips and an attached rubber band ([Fig. 1 c]), providing further access to the dissection plane. Step by step, a tunnel was created along the axis of the polyp. The tunnel was then enlarged on both sides to create a pocket ([Fig. 1 d]). After half of the lesion had been dissected, additional counteraction was provided in a similar fashion to modify the axis of dissection. In addition, dissection with an IT knife (Olympus) under saline was performed in areas with suboptimal lifting from the muscularis propria [3]. The lesion was removed en bloc, after detachment with a loop cutter ([Fig. 1 e]). The procedure lasted 4 hours and was uneventful. Pathology revealed a 6-cm tubulovillous adenoma with low grade dysplasia, and confirmed an R0 resection.
BUCHAREST
Journal: JAMA (1934)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Association between two mass-gathering outdoor events and incidence of SARS-CoV-2 infections during the fifth wave of COVID-19 in north-east Spain: A population-based control-matched analysis
Authors: Clara Suñer, Ermengol Coma, Dan Ouchi, Eduardo Hermosilla, Bàrbara Baro, Miquel Àngel Rodríguez-Arias, Jordi Puig, Bonaventura Clotet, Manuel Medina, Oriol Mitjà
Journal: The Lancet Regional Health - Europe (2022)

Many countries have resumed mass-gathering events like music festivals, despite the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spreading. In this study, we aimed to assess the effect of two mass-gathering outdoor events, held during a peak of SARS-CoV-2 transmission, on COVID-19 incidence.This was a retrospective, population-based control-matched analysis. The study population included attendees to two outdoor music festivals held in Catalonia (North-East Spain). The primary objective was to compare the incidence of COVID-19 within the 3-to-10 days following the event between attendees and a population-based control group.The analysis included 18,275 and 27,347 attendees to the first and second festivals, respectively, and their corresponding controls. The post-festival 7-day cumulative COVID-19 incidence among attendees and controls was 4.14% (95% CI 3.86-4.44) vs. 1.69% (1.51-1.88) for the first festival (RR 2.46; 2.16-2.80), and 2.42% (2.35-2.61) and 1.10% (0.99-1.2) for the second festival (RR 2.19; 1.92-2.51). COVID-19 incidence among immunized individuals was also two-fold higher in attendees than in controls. Previous COVID-19 infection, vaccination, and adequate mask-wearing were significantly associated with a lower risk of COVID-19 infection after the events.Despite the proven effectiveness of preventive measures such as Ag-RDT screening, mask-wearing and vaccination, caution should be taken when holding these events during a period of high community SARS-CoV-2 transmission.Crowdfunding campaign YoMeCorono (https://www.yomecorono.com/) and the Generalitat de Catalunya.
Fermentation, Infection and Immunity. A New Theory of These Processes which Unifies their Primary Causation and Places the Explanation of their Phenomena in Chemistry, Biology, and Dynamics of Molecular Physics.
Journal: JAMA (1893)

The author of this little book will be recollected as having described a micrococcus in the blood of patients suffering from dengue or breakbone fever; his observations, though not yet confirmed on account of the absence of opportunity as no epidemic has occurred during the last two years or so, are about the only ones extant on the specific etiology of dengue. McLaughlin's present work is an interesting contribution to the study of the processes and problems indicated in the title, problems just now occupying the minds of students and investigators the world over. The book really consists of a number of articles published here and there during the the last few years in which the etiology of acute, infectious diseases has been discussed from various standpoints; to these articles considerable new matter has been added. The "physical" theory of immunity here introduced is elaborated in an interesting manner, the
ADVANTAGES OF PROCTOCLYSIS BY THE FLUSH METHOD
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Cerebral circulation
Authors: C. H. Millikan
Journal: JAMA (1978)

THE MODERN era of cerebrovascular disease began in 1946 with a landmark paper by Kubik and Adams.<sup>1</sup>A description of antecedent symptoms and those of onset as well as of neurological abnormalities of the final illness was provided for each of the 18 patients. The authors did not discuss the possible importance of antecedent symptoms, ie, attacks, in six patients and probable warning symptoms in four others. These episodes are now called transient ischemic (focal cerebral) attacks (TIA). <h3>Review of the Literature</h3> The report of the nitrous oxide method for the quantitative determination of cerebral blood flow in man in 1948 by Kety and Schmidt<sup>2</sup>opened an era that has seen the publication of thousands of papers about cerebral blood flow in animals and man. The Kety and Schmidt method, ie, Fick principle, has been modified in a number of ways, particularly with technical improvements, including computer analysis.
DNA methylation reveals distinct cells of origin for pancreatic neuroendocrine carcinomas and pancreatic neuroendocrine tumors
Authors: Tincy Simon, Pamela Riemer, Armin Jarosch, Katharina Detjen, Annunziata Di Domenico, Felix Bormann, Andrea Menne, Slim Khouja, Nanna Monjé, Liam H. Childs, Dido Lenze, Ulf Leser, Florian Rossner, Markus Morkel, Nils Blüthgen, Marianne Pavel, David Horst, David Capper, Ilaria Marinoni, Aurel Perren, Soulafa Mamlouk, Christine Sers
Journal: Genome Medicine (2022)

Pancreatic neuroendocrine neoplasms (PanNENs) fall into two subclasses: the well-differentiated, low- to high-grade pancreatic neuroendocrine tumors (PanNETs), and the poorly-differentiated, high-grade pancreatic neuroendocrine carcinomas (PanNECs). While recent studies suggest an endocrine descent of PanNETs, the origin of PanNECs remains unknown.We performed DNA methylation analysis for 57 PanNEN samples and found that distinct methylation profiles separated PanNENs into two major groups, clearly distinguishing high-grade PanNECs from other PanNETs including high-grade NETG3. DNA alterations and immunohistochemistry of cell-type markers PDX1, ARX, and SOX9 were utilized to further characterize PanNECs and their cell of origin in the pancreas.Phylo-epigenetic and cell-type signature features derived from alpha, beta, acinar, and ductal adult cells suggest an exocrine cell of origin for PanNECs, thus separating them in cell lineage from other PanNENs of endocrine origin.Our study provides a robust and clinically applicable method to clearly distinguish PanNECs from G3 PanNETs, improving patient stratification.
Major Update 2: Remdesivir for Adults With COVID-19: A Living Systematic Review and Meta-analysis for the American College of Physicians Practice Points
Authors: Anjum S. Kaka, Roderick MacDonald, Eric J. Linskens, Lisa Langsetmo, Kathryn Vela, Wei Duan-Porter, Timothy J. Wilt
Journal: Annals of Internal Medicine (2022)

Background: Remdesivir is approved for the treatment of adults hospitalized with COVID-19. Purpose: To update a living review of remdesivir for adults with COVID-19. Data Sources: Several electronic U.S. Food and Drug Administration, company, and journal websites from 1 January 2020 through 19 October 2021. Study Selection: English-language, randomized controlled trials (RCTs) of remdesivir for COVID-19. Data Extraction: One reviewer abstracted, and a second reviewer verified data. The Cochrane Risk of Bias Tool and GRADE (Grading of Recommendations Assessment, Development and Evaluation) method were used. Data Synthesis: Since the last update (search date 9 August 2021), 1 new RCT and 1 new subtrial comparing a 10-day course of remdesivir with control (placebo or standard care) were identified. This review summarizes and updates the evidence on the cumulative 5 RCTs and 2 subtrials for this comparison. Our updated results confirm a 10-day course of remdesivir, compared with control, probably results in little to no mortality reduction (5 RCTs). Updated results also confirm that remdesivir probably results in a moderate increase in the proportion of patients recovered by day 29 (4 RCTs) and may reduce time to clinical improvement (2 RCTs) and hospital length of stay (4 RCTs). New RCTs, by increasing the strength of evidence, lead to an updated conclusion that remdesivir probably results in a small reduction in the proportion of patients receiving ventilation or extracorporeal membrane oxygenation at specific follow-up times (4 RCTs). New RCTs also alter the conclusions for harms—remdesivir, compared with control, may lead to a small reduction in serious adverse events but may lead to a small increase in any adverse event. Limitation: The RCTs differed in definitions of COVID-19 severity and outcomes reported. Conclusion: In hospitalized adults with COVID-19, the findings confirm that remdesivir probably results in little to no difference in mortality and increases the proportion of patients recovered. Remdesivir may reduce time to clinical improvement and may lead to small reductions in serious adverse events but may result in a small increase in any adverse event. Primary Funding Source: U.S. Department of Veterans Affairs.
Bronchiectasis, the Latest Eosinophilic Airway Disease: What About the Microbiome?
Authors: Dave Singh, Chris Brightling
Journal: American Journal of Respiratory and Critical Care Medicine (2022)

"Bronchiectasis the Latest Eosinophilic Airway Disease - What About the Microbiome?." American Journal of Respiratory and Critical Care Medicine, 0(ja), pp. –
THE IMPACT OF NATIONAL CANCER ACT
Journal: JNCI Journal of the National Cancer Institute (1991)

THE IMPACT OF NATIONAL CANCER ACT Get access JNCI: Journal of the National Cancer Institute, Volume 83, Issue 24, 18 December 1991, Pages S-1–S-16, https://doi.org/10.1093/jnci/83.24.S-1 Published: 18 December 1991
LETTER FROM NEW YORK.
Journal: JAMA (1889)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Primary Studies for Nurses. A Text-Book for First Year Pupil Nurses Containing Courses of Studies in Anatomy, Physiology, Chemistry, Hygiene, Bacteriology, Therapeutics and Materia Medica, Dietetics and Invalid Cookery.
Journal: JAMA (1928)

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