tbuckley/cabot-search huggingface dataset:
ANALYSIS OF THE NUMBER OF ENDOSCOPIC ESOPHAGEAL DILATIONS PERFORMED IN BRAZIL DURING THE COVID-19 PANDEMIC
Authors: T. Correa
Journal: Endoscopy (2022)

Aims Considering the high transmissibility of COVID-19, health systems can become overwhelmed and the lack of resources is a major concern in low- and middle-income countries including Brazil. Endoscopic esophageal dilation is a procedure performed for symptomatic relief of esophageal strictures and may be impacted by the health system oversaturation due to COVID-19. The aim of this study was to evaluate the number of endoscopic esophageal dilations performed in Brazil during the COVID-19 pandemic.
MULTICENTER STUDY OF COLD VERSUS HOT EMR FOR LARGE DUODENAL ADENOMAS
Authors: A. Capogreco, M. Spadaccini, R. Maselli, C. Hassan, P.A. Galtieri, G. Pellegatta, A. Anderloni, A. Fugazza, S. Carrara, E.C. Ferrara, M. Colombo, E. Vespa, N. Pugliese, T. Parigi, G. Schachschal, A. Creutzfeldt, P. Bhandari, A. Meining, T. Rosch, A. Repici
Journal: Endoscopy (2022)

Aims Hot-snare resection of larger non-ampullary duodenal adenomas(NADA)(≥2cm) is characterised by sunstantial complication rates.Cold-snare resection was shown in the colon to decrease adverse events.Accordingly,we assessed the performance of cold-EMR in the duodenum in comparison to hot-EMR.
COLORECTAL CANCER RISK AND ADENOMA DETECTION RATE IN IMMUNOCHEMICAL FAECAL TEST SCREENING PROGRAMS
Authors: G. Antonelli, M. Zorzi, J. Battagello, C. Hassan
Journal: Endoscopy (2022)

Aims Colorectal Cancer (CRC) screening programs based on Faecal Immunochemical Test (FIT) represent the standard of care for population-based intervention. Its benefit depends on identification of neoplasia at colonoscopy in FIT+subjects. Thus, its quality as measured by Adenoma Detection Rate (ADR) may affect its outcomes.
Why all MODY variants are dominantly inherited: a hypothesis
Authors: Meihang Li, Jean-Baptiste Rivière, Constantin Polychronakos
Journal: Trends in Genetics (2021)

Maturity-onset diabetes in the young (MODY) comprises monogenic phenotypes of young-onset, insulinopenic diabetes. All its forms are dominantly inherited. Why? Are the pancreatic β cells only harmed by heterozygous variants? We propose that recessive MODYs do exist but have escaped detection due to lack of family history suggestive of monogenic inheritance.
MALIGNANT POLYPS: ONE SIZE DOES NOT FIT ALL
Authors: C. Nascimento, J. Revés, B. Morão, M. Cravo, J. Cortez Pinto, L. Glória
Journal: Endoscopy (2022)

Aims The presence of high-risk features (HRF) predicting lymph node metastasis (LNM) and endoscopic piecemeal resection favors surgical approach in T1 colorectal cancer (CRC). The lack of consensus as to what constitutes HRF makes clinical decisions very challenging. Aim: to evaluate oncologic outcomes after malignant polyps’ endoscopic resection.
ESOPHAGEAL PERFORATION AFTER VOICE PROSTHESIS PLACEMENT. ENDOSCOPIC THERAPY WITH ESO-SPONGE
Authors: A. Fernandez-Simon, O. Sendino, H. Cordova, L. Pujol-Vila, F.X. Aviles-Jurado
Journal: Endoscopy (2022)

We report a case of a 56 year old male, with a history of a total laryngectomy due to a supraglottic squamous cell carcinoma, who presented with a large retroesophageal perforation after a voice prosthesis placement. After three weeks of endoscopic vacuum therapy, requiring a total of 7 sponges, the closure of the esophageal defect was achieved.
EPIDEMIOLOGICAL CHARACTERISTICS AND PREDICTIVE FACTORS OF RECURRENCE AND MORTALITY OF UPPER GASTROINTESTINAL BLEEDING (UGB) UNRELATED TO PORTAL HYPERTENSION (PH)
Authors: F.Z. Agoune, K. Layaida, Y. Zair, M.A. Boussafsaf, N. Kaddache, K. Belhocine, S. Khouitar, S. Berkane
Journal: Endoscopy (2022)

Aims UGB is one of the major emergencies in gastroenterology; its overall mortality remains high despite the major advances made in its therapeutic management. The main aim is to describe the epidemiological characteristics of UGB unrelated to PH and identify predictive factors for recurrence and mortality.
PROFITABILITY OF THE SHARKCORE ECHOENDOSCOPY BIOPSY NEEDLE IN THE STUDY OF MEDIASTINAL PATHOLOGY
Authors: F. Santos Santamarta, B.A. Moreira da Silva, Á.M. Montero Moretón, E. González de Castro, L.F. Aguilar Argeñal, D. Robles de la Osa, F. Berzal Cantalejo, L. Pérez Citores, M. Cimavilla Román, M. Curieses Luengo, J. Barcenilla Laguna, F. Rancel Medina, J. Santos Fernández, S. Maestro Antolín, A.G. Pérez Millán
Journal: Endoscopy (2022)

Aims Endoscopic ultrasound allows puncture sampling of thoracic structures from the esophagus. Formerly, punctures were performed with fine needles that only allowed cytological diagnosis; devices have now larger-caliber needles, obtaining cell blocks that preserve tissues architecture being possible to perform immunohistochemical techniques to optimize diagnoses. The aim of the study is to evaluate the SharkCore 22G biopsy needle (Covidien-Medtronic) to study mediastinal pathology.
DESMOPLASTIC STROMA IDENTIFICATION AS A QUALITY MARKER FOR RELIABLE HISTOLOGIC SAMPLES OBTAINED BY EUS IN SOLID PANCREATIC LESIONS. A NEW STANDARD FOR ADEQUACY
Authors: G. Perez Alvarez, I. Husain Calzada, C.A. Vargas Gonzalez, F.X. Cano Calderero, E. Junquera Alonso, M. Terroba Alonso, C. Cerrella Cano, J. Alonso de la Campa, G. Meijide Santos, L. Perez Vidal, M. Crespo Sanchez, L. Sanchez Dominguez
Journal: Endoscopy (2022)

Aims To evaluate the presence of desmoplastic stroma as a potential new quality marker of the fine needle biopsy (FNB) samples in pancreatic ducal adenocarcinoma (PDAC). To illustrate that a simplified strategy to obtain and process the tissue using histologic needles allows an adequate high-quality sample, including the identification of stroma.
Building causal knowledge in behavior genetics
Authors: James W. Madole, K. Paige Harden
Journal: Behavioral and Brain Sciences (2022)

Behavior genetics is a controversial science. For decades, scholars have sought to understand the role of heredity in human behavior and life-course outcomes. Recently, technological advances and the rapid expansion of genomic databases have facilitated the discovery of genes associated with human phenotypes such as educational attainment and substance use disorders. To maximize the potential of this flourishing science, and to minimize potential harms, careful analysis of what it would mean for genes to be causes of human behavior is needed. In this paper, we advance a framework for identifying instances of genetic causes, interpreting those causal relationships, and applying them to advance causal knowledge more generally in the social sciences. Central to thinking about genes as causes is counterfactual reasoning, the cornerstone of causal thinking in statistics, medicine, and philosophy. We argue that within-family genetic effects represent the product of a counterfactual comparison in the same way as average treatment effects (ATEs) from randomized controlled trials (RCTs). Both ATEs from RCTs and within-family genetic effects are shallow causes: They operate within intricate causal systems (non-unitary), produce heterogeneous effects across individuals (non-uniform), and are not mechanistically informative (non-explanatory). Despite these limitations, shallow causal knowledge can be used to improve understanding of the etiology of human behavior and to explore sources of heterogeneity and fade-out in treatment effects.
EFFECTIVE REDUCTION OF ESOPHAGEAL STENT MIGRATION RATE WITH A NOVEL OVER-THE-SCOPE FIXATION DEVICE (STENTFIX OTSC)
Authors: M. Schiemer, D. Bettinger, J. Mueller, M. Schultheiss, H. Schwacha, P. Hasselblatt, R. Thimme, A. Schmidt, A. Kuellmer
Journal: Endoscopy (2022)

Aims Self-expandable metal stent (SEMS) placement is routinely performed in a variety of benign and malignant gastrointestinal diseases. One of the most frequent adverse events after esophageal SEMS placement is stent migration. We evaluated a novel over-the-scope clip device (stentfix OTSC​, Ovesco Endoscopy, Tuebingen, Germany) designed and approved for SEMS fixation.
TRANSABDOMINAL SEMS PLACEMENT AS A RESCUE THERAPY TO DRAIN POST-ACUTE PANCREATITIS COLLECTION: A CASE REPORT (WITH VIDEO)
Authors: S. Torrisi, A. Brunori, R. Manta, U. Germani, D. Castellani
Journal: Endoscopy (2022)

A 60-year-old female was hospitalized for a severe pancreatitis complicated by a large infected abdominal capsuled collection in the iliac area. A radiological guided drainage (14 Fr) was placed and connected to a Redon vacuum bottle without improvement due to solid necrotic tissue obstruction. The external drainage was removed and an oesophageal FC-SEMS (Taewoong Niti-S; 120x20 mm) was placed; endoscopic necrosectomy was performed pushing a gastroscope (UGT-By Olympus) through the SEMS until resolution of the collection.
PHLEGMONOUS GASTRITIS: CASE REPORT AND LITERATURE REVIEW
Authors: L. Tarasenka, S. Polishchuk, Y. Dombrovsky
Journal: Endoscopy (2022)

Methods Female, 50 y.o. admitted on the 12th day from symptoms onset with suspected gastric cancer. Upon presentation she had no complaints but a history of abdominal pain, nausea, diarrhea, subfebrile temperature for 3 days which subsided with ceftriaxone prescribed for suspected gastroenteritis. Medical history is significant for arthrosis and COVID-19. She is taking aspirin and NSAIDs. Physical examination revealed mild epigastric tenderness without guarding, Bp – 150/90 mm Hg, heart rate – 78 bpm, body temperature – 37,2℃, CRP – 47,9 mg/l, Leu – 18,5 g/L, ESR – 37 mm/h. Test for syphilis was negative.She was treated with levofloxacin and metronidazole, discharged on day 15.
ENDOSCOPIC FULL-THICKNESS RESECTION OF A DUODENAL GIST WITH EXTRALUMINAL COMPONENT BY NOTES: TRACTION AND SUTURES
Authors: H. Uchima, E. Garsot, J. Colán-Hernández, M. Viciano, A. Clavell, I. Marín, N. Caballero, I. Iborra, M. Puig, A. Calm, M. Fortuny, E. Domènech, V. Moreno
Journal: Endoscopy (2022)

A 68 year-old male with previous history of Billroth I reconstruction, and radical cystectomy with Bricker, presented with a 2.5cm GIST with extraluminal component confirmed histologically on the third duodenal part.
ESOPHAGOGASTRODUODENAL FINDINGS IN PATIENTS WITH INTRADUCTAL PAPILLARY MUCINOUS NEOPLASMS (IPMNS)
Authors: D. Ben Ami Shor, D. Zelnik Yovel, M. Khader, R. Tzadok, E. Scapa, M. Shnell, I. Bar Yishay, T. Ziv Baran, O. Shibolet
Journal: Endoscopy (2022)

Aims The association between intraductal papillary mucinous neoplasms (IPMNs) and extra-pancreatic malignancies is controversial. Our aim was to compare the esophagogastroduodenal findings among patients with IPMN and patients with no known IPMN.
INCREMENTAL YIELD OF ARTIFICIAL INTELLIGENCE IN A FECAL OCCULT BLOOD TEST BASED ORGANIZED SCREENING POPULATION PROGRAM
Authors: E.V. Pesatori, S.M. Milluzzo, P. Cesaro, S. Piccirelli, F. Catino, A. Quadarella, N. Olivari, L. Minelli Grazioli, M. Codazzi, A. Bizzotto, C. Hassan, C. Spada
Journal: Endoscopy (2022)

Aims Fecal Occult Blood Test (FOBT) is the first line test in organized Colorectal Cancer (CRC) screening settings in several countries. Artificial Intelligence (AI) can potentially improve diagnostic performance of colonoscopy, reducing adenoma miss rate and interval CRC. The aim of the study was to compare the diagnostic yield of AI-assisted colonoscopy versus standard colonoscopy (SC).
ENDOSCOPIC GASTROPLASTY IN ROUTINE CLINICAL PRACTICE: PROSPECTIVE REGISTRY TRIAL
Authors: M. De Siena, V. Pontecorvi, V. Bove, M.V. Matteo, G. Carlino, G. Giannetti, C. Massari, N. Antonini, I. Boškoski, G. Costamagna
Journal: Endoscopy (2022)

Aims The total number of bariatric endoscopic procedures is constantly increasing in routine clinical practice. Endoscopic gastroplasty (ESG) is safe and effective in patients with class I and II obesity associated with diet and lifestyle modifications. We present our results from a prospective clinical trial evaluating the role of the Endomina system (Endo Tools therapeutics, Belgium). The aim was to evaluate the mean total body weight loss (TBWL) and the mean excess weight loss (EWL) at 6 and 12 months.
EUS-GUIDED JEJUNO-JEJUNAL ANASTOMOSIS AS SALVAGE THERAPY FOR A COMPLEX BENIGN GASTRIC OUTLET OBSTRUCTION
Authors: E. Perez-Cuadrado-Robles, G. Perrod, A. Lansier, J. Palle, A. Mariani, C. Cellier, G. Rahmi
Journal: Endoscopy (2022)

Lumen-apposing metal stents (LAMS) are gaining ground in the treatment of benign gastric outlet obstruction (GOO). A 76 years-old male patient with recurrent GOO following a surgical gastrojejunostomy. An upper-GI endoscopy revealed a kinking of the proximal efferent limb resulting in a long complex stricture.
TEXTURE AND COLOR ENHANCING IMAGING (TXI) INCREASES ADENOMA DETECTION RATE IN COLONOSCOPY: INTERIM ANALYSIS OF A RANDOMIZED CONTROLLED TRIAL
Authors: G. Antonelli, G. Bevivino, A. Ebigbo, S. Pecere, F. Cereatti, N. Akizue, M. Di Fonzo, M. Coppola, F. Barbaro, A. Caruso, K. Okimoto, C. Antenucci, T. Matsumura, G. Zerboni, C. Grossi, M. Meinikheim, G. Papparella, C. Spada, G. Costamagna, H. Messmann, C. Hassan, F. Iacopini
Journal: Endoscopy (2022)

Aims Virtual chromoendoscopy techniques to enhance imaging during colonoscopy have shown controversial results in increasing Adenoma Detection Rate (ADR). A new imaging modality, Texture and Color Enhancing Imaging (TXI, Exera X1, Olympus, Japan) was recently proposed as a substitute to standard white light (WLI) colonoscopy. We performed an interim analysis of an ongoing multicenter, randomized trial to assess the efficacy of TXI in detection of colorectal neoplasia.
EVALUATION OF 2 DIFFERENT REGIMENS OF COLON PREPARATION FOR AN ADVANCED CLEANING USING A 2LT PEG-CS WITH SIMETHICONE: A RANDOMIZED, CONTROLLED STUDY – THE ERACLES STUDY
Authors: L. Pasquale, G. Grande, R.M. Zagari, A. Pisani, P. Da Massa Carrara, B. Germanà, E. Ciliberto, G. Cengia, A. Lamazza, L. Laterza, C. Stillitano, D. Picascia, R. Conigliaro, G. Galloro
Journal: Endoscopy (2022)

Aims Although the split dose regimen is recommended as bowel preparation in patients underwent to morning colonoscopy, its use in daily practice remains limited. Conversely, the classic day before regimen account for up to 35% of inadeguate bowel cleansing.
Genomic Impact of Whaling in North Atlantic Fin Whales
Authors: Magnus Wolf, Menno de Jong, Sverrir Daníel Halldórsson, Úlfur Árnason, Axel Janke
Journal: Molecular Biology and Evolution (2022)

It is generally recognized that large-scale whaling in the 19th and 20th century led to a substantial reduction of the size of many cetacean populations, particularly those of the baleen whales (Mysticeti). The impact of these operations on genomic diversity of one of the most hunted whales, the fin whale (Balaenoptera physalus), has remained largely unaddressed because of the paucity of adequate samples and the limitation of applicable techniques. Here, we have examined the effect of whaling on the North Atlantic fin whale based on genomes of 51 individuals from Icelandic waters, representing three temporally separated intervals, 1989, 2009 and 2018 and provide a reference genome for the species. Demographic models suggest a noticeable drop of the effective population size of the North Atlantic fin whale around a century ago. The present results suggest that the genome-wide heterozygosity is not markedly reduced and has remained comparable with other baleen whale species. Similarly, there are no signs of apparent inbreeding, as measured by the proportion of long runs of homozygosity, or of a distinctively increased mutational load, as measured by the amount of putative deleterious mutations. Compared with other baleen whales, the North Atlantic fin whale appears to be less affected by anthropogenic influences than other whales such as the North Atlantic right whale, consistent with the presence of long runs of homozygosity and higher levels of mutational load in an otherwise more heterozygous genome. Thus, genome-wide assessments of other species and populations are essential for future, more specific, conservation efforts.
LAG-3xPD-L1 bispecific antibody potentiates antitumor responses of T cells through dendritic cell activation
Authors: Eunsil Sung, Minkyung Ko, Ju-young Won, Yunju Jo, Eunyoung Park, Hyunjoo Kim, Eunji Choi, Ui-jung Jung, Jaehyoung Jeon, Youngkwang Kim, Hyejin Ahn, Da-som Choi, Seunghyun Choi, Youngeun Hong, Hyeyoung Park, Hanbyul Lee, Yong-Gyu Son, Kyeongsu Park, Jonghwa Won, Soo Jin Oh, Seonmin Lee, Kyu-pyo Kim, Changhoon Yoo, Hyun Kyu Song, Hyung-seung Jin, Jaeho Jung, Yoon Park
Journal: Molecular Therapy (2022)

Several preclinical studies demonstrate that antitumor efficacy of programmed cell death-1 (PD-1)/programmed death-ligand 1 (PD-L1) blockade can be improved by combination with other checkpoint inhibitors. Lymphocyte-activation gene 3 (LAG-3) is an inhibitory checkpoint receptor involved in T cell exhaustion and tumor immune escape. Here, we describe ABL501, a bispecific antibody targeting LAG-3 and PD-L1 in modulating immune cell responses against tumors. ABL501 that efficiently inhibits both LAG-3 and PD-L1 pathways enhances the activation of effector CD4
VARICEAL BLEDING DIFFERENCES BETWEEN 2010 AND 2020 – A SINGLE CENTRE EXPERIENCE
Authors: S. Pelajić, D. Budimir, D. Bakula, M. Nikolić, V. Tomašić, M. Kovačina, D. Hrabar, T. Pavić
Journal: Endoscopy (2022)

Aims The aim of this study was to demonstrate differences in epidemiological, clinical and endoscopic characteristics of variceal bleeding and outcomes between
QUALITY INDICATORS FOR COLONOSCOPY IN EGYPT: A PROSPECTIVE MULTICENTER STUDY
Authors: S. Afify, M. Tag-Adeen, A. Abu-Elfatth, A. Eid, A. Nageh, A. Alzamzamy, F. El-Raey, A.N Basiony, M. Abdelghani, D. Abdeltawab, R.M Ahmed, H. Nasr, M.N. Alkady, W. Ibrahim, O. Elshaarawy, H. Amer, M. Thoufeeq, M. Alboraie
Journal: Endoscopy (2022)

Aims Colonoscopy is the gold standard colorectal cancer screening method. Despite widely available in Egypt, no sufficient data about quality performances exists. We studied 13 quality indicators in 8 centres aiming to attain a representative image about quality of colonoscopy in Egypt.
‘DIRECT ACCESS’ ENDOSCOPY – CAN WE REDUCE OUTPATIENT BURDEN EVEN FURTHER?
Authors: I. Hutchesson, L. Ainsworth, H. McRobbie, R. Patel
Journal: Endoscopy (2022)

Aims ‘Direct access’ endoscopy (DAE) allows patients to be triaged straight to gastroscopy or colonoscopy prior to seeing a specialist in order to facilitate an efficient diagnosis and treatment plan. Concerns remain about DAE contributing to an increase in routine clinic review that follows procedures, and thus adding strain to an already over-burdened outpatient service. We aimed to review the outcomes of patients undergoing DAE, specifically to assess the proportion resulting in avoidable outpatient appointments.
Peripheral monocyte–derived cells counter amyloid plaque pathogenesis in a mouse model of Alzheimer’s disease
Authors: Ping Yan, Ki-Wook Kim, Qingli Xiao, Xiucui Ma, Leah R. Czerniewski, Haiyan Liu, David R. Rawnsley, Yan Yan, Gwendalyn J. Randolph, Slava Epelman, Jin-Moo Lee, Abhinav Diwan
Journal: Journal of Clinical Investigation (2022)

Microglia, the parenchymal tissue macrophages in the brain, surround amyloid plaques in brains of individuals with Alzheimer's disease (AD) but are ineffective at clearing amyloid to mitigate disease progression. Recent studies in mice indicate that microglia are derived exclusively from primitive yolk sac hematopoiesis and self-renew without contribution from ontogenically distinct monocytes/macrophages of definitive adult hematopoietic origin. Using a genetic fate-mapping approach to label cells of definitive hematopoietic origin throughout life span, we discovered that circulating monocytes contribute 6% of plaque-associated macrophages in aged AD mice. Moreover, peripheral monocytes contributed to a higher fraction of macrophages in the choroid plexus, meninges, and perivascular spaces of aged AD mice versus WT control mice, indicating enrichment at potential sites for entry into the brain parenchyma. Splenectomy, which markedly reduced circulating Ly6Chi monocytes, also reduced abundance of plaque-associated macrophages of definitive hematopoietic origin, resulting in increased amyloid plaque load. Together, these results indicate that peripherally derived monocytes invade the brain parenchyma, targeting amyloid plaques to reduce plaque load.
EFFECT OF AN ARTIFICIAL INTELLIGENCE SYSTEM IN THE DETECTION OF DYSPLASIAS DURING COLONOSCOPY IN PATIENTS WITH LONG-STANDING ULCERATIVE COLITIS. PRELIMINARY RESULTS
Authors: A. López-Serrano, R. Díaz, P. Besó, A. Algarra, F.J. Santonja, A. Machancoses, P. Del Pozo, P. Latorre, H. Tomás, J.M. Paredes
Journal: Endoscopy (2022)

Aims Computerized Artificial Intelligence (AI) systems have been developed to increase the detection of colonic adenomas. High-definition virtual chromoendoscopy (VCE) in addition to targeted biopsies is one of the recommended techniques for surveillance of dysplasia in long-standing ulcerative colitis (UC). However, there is no data on the usefulness of AI in this setting. The aim was to assess the effectiveness of AI-assisted colonoscopy in dysplasia detection in patients with long-standing UC.
WHEN VILLOUS ATROPHY IS NOT JUST COELIAC – A CASE OF AUTOIMMUNE ENTEROPATHY
Authors: O. Pelkonen, B. Norton, S. Mann
Journal: Endoscopy (2022)

Aims Autoimmune enteropathy (AIE) is an extremely rare cause of seronegative villous atrophy that represents a diagnostic challenge for the general gastroenterologist. It can be a life-threatening condition characterised by intractable diarrhoea, severe malabsorption and requires systemic immunosuppression.
THE IMPORTANCE OF CHOLANGIOSCOPY IN THE DIAGNOSIS OF INTRADUCTAL LESIONS OF THE BILIARY TRACT
Authors: R.O. Saraiva, G. Simões, M.I. Canha, M. Rocha, R. Loureiro, G. Ramos, A.M. Cordeiro, E. Vigia, A.M. Dias, J. Coimbra
Journal: Endoscopy (2022)

Results Male of 41-years-old with postprandial infarction, nausea and weight loss (5 kg, 7% total weight) with two years evolution. On examination, he presented scleral icterus. Analytically, conjugated hyperbilirubinemia (BT 3.62mg/dL/Bd 2.60mg/dL) and cytocholestasis (AST 102U/L, ALT 144U/L, FA 330U/L, GGT 681U/L) stood out.
107P Impact of COVID-19 pandemic on breast cancer neoadjuvant therapy: A retrospective institutional analysis
Authors: M.C. Baptista Freitas, C. Lopes de Almeida, A.C. Valente, M.J. Costa, I.C. Nogueira Costa, J.S. Reis, N.T. Tavares, I.J. Dionísio de Sousa, D.P.S. Almeida, C.L.B. Caeiro, I.M. Augusto, L.M. Nunes Aguas, M. Barbosa
Journal: Annals of Oncology (2022)
The respiratory tract microbiome: moving from correlation to causation
Authors: Richard Morton, Aran Singanayagam
Journal: European Respiratory Journal (2022)

<b>C. Rigauts and co-workers provide insight into a previously unrecognised role for the airway commensal <i>Rothia mucilaginosa</i> in attenuating proinflammatory responses to <i>P. aeruginosa</i>, an effect demonstrated consistently across a range of experimental models</b> https://bit.ly/3EIs9nv
A PROSPECTIVE STUDY OF REAL-TIME COMPUTER-AIDED CHARACTERIZATION FOR COLORECTAL LESIONS -DIAGNOSTIC PERFORMANCE AND IMPACT ON HUMAN DIAGNOSIS-
Authors: M. Misawa, S.-e. Kudo, Y. Miyata, Y. Minegishi, Y. Mori, H. Nakamura, Y. Maeda, K. Ichimasa, T. Kudo, K. Wakamura, H. Miyachi, F. Ishida
Journal: Endoscopy (2022)

Aims Recently artificial intelligence assisted computer-aided diagnosis (CADx) is catching attention. The aim of this study was to clarify newly developed CADx’s performance and how does AI output affect human diagnosis, in a prospective study.