tbuckley/cabot-search huggingface dataset:
Detection of Clonal Plasma Cells in POEMS Syndrome Using Multiparameter Flow Cytometry
Authors: Arata Ishii, Shokichi Tsukamoto, Naoya Mimura, Yurie Nagai, Shinichiro Matsui, Sanshiro Nakao, Asuka Shibamiya, Yutaro Hino, Kensuke Kayamori, Nagisa Oshima-Hasegawa, Tomoya Muto, Shio Mitsukawa, Yusuke Takeda, Tomoki Suichi, Sonoko Misawa, Chikako Ohwada, Koutaro Yokote, Satoshi Kuwabara, Chiaki Nakaseko, Hiroyuki Takamatsu, Emiko Sakaida
Journal: Blood (2021)
Prevalence and Characteristics of Subjective Cognitive Decline Among Unpaid Caregivers Aged ≥45 Years — 22 States, 2015–2019
Authors: Eva M. Jeffers, Erin D. Bouldin, Lisa C. McGuire, Kenneth A. Knapp, Roshni Patel, Dana Guglielmo, Christopher A. Taylor, Janet B. Croft
Journal: MMWR Morbidity and Mortality Weekly Report (2021)

Approximately 20% of U.S. adults are unpaid caregivers (caregivers) (1) who provide support to a family member or friend with a health condition or disability. Although there are benefits to caregiving, it can negatively affect caregivers' physical and mental health (2-4). Much of the assistance caregivers provide, such as administering medications or financial management, relies on cognitive ability, but little is known about caregivers' cognitive functioning. Subjective cognitive decline (SCD), the self-reported experience of worsening or more frequent confusion or memory loss over the past year (5), could affect caregivers' risk for adverse health outcomes and affect the quality of care they provide. CDC analyzed SCD among caregivers aged ≥45 years through a cross-sectional analysis of data from 22 states in the 2015-2019 Behavioral Risk Factor Surveillance System (BRFSS). Among adults aged ≥45 years, SCD was reported by 12.6% of caregivers who provided care to a family member or friend with a health condition or disability in the past 30 days compared with 10.2% of noncaregivers (p<0.001). Caregivers with SCD were more likely to be employed, men, aged 45-64 years, and have chronic health conditions than were noncaregivers with SCD. Caregivers with SCD were more likely to report frequent mental distress, a history of depression, and frequent activity limitations than were caregivers without SCD. SCD among caregivers could adversely affect the quality of care provided to care recipients. Understanding caregivers' cognitive health and the types of care provided is critical to maintaining the health, well-being, and independence of the caregiving dyad. Health care professionals can support patients and their patients' caregivers by increasing awareness among caregivers of the need to monitor their own health. The health care team can work with caregivers to identify potential treatments and access supports that might help them in their caregiving role and compensate for SCD.
Early Versus Late Discontinuation of Maintenance Therapy in Multiple Myeloma
Authors: Jordan Nunnelee, Muhammad Salman Faisal, Qiuhong Zhao, Francesca Cottini, Patrick Elder, Ashley E. Rosko, Maria Chaudhry, Abdullah Khan, Srinivas Devarakonda, Naresh Bumma, Don M Benson, Yvonne A. Efebera, Nidhi Sharma
Journal: Blood (2021)
Development and Validation of a Novel Prognostic Nomogram Model and a Web-Based Survival Rate Calculator for Diffuse Large B-Cell Lymphoma in the Rituximab Era
Authors: Qiaofeng Zhong, Haizhu Chen, Yan Qin, Xiaohui He, Sheng Yang, Shengyu Zhou, Peng Liu, Yuankai Shi, Hongmei Jing
Journal: Blood (2021)
Tuberculosis contact investigation following the stone-in-the-pond principle in the Netherlands – Did adjusted guidelines improve efficiency?
Authors: Sarah van de Berg, Connie Erkens, Christiaan Mulder
Journal: Eurosurveillance (2021)

Background In low tuberculosis (TB) incidence countries, contact investigation (CI) requires not missing contacts with TB infection or disease without unnecessarily evaluating non-infected contacts. Aim We assessed whether updated guidelines for the stone-in-the-pond principle and their promotion improved CI practices. Methods This retrospective study used surveillance data to compare CI outcomes before (2011–2013) and after (2014–2016) the guideline update and promotion. Using negative binomial regression and logistic regression models, we compared the number of contacts invited for CI per index patient, the number of CI scaled-up according to the stone-in-the-pond principle, the TB and latent TB infection (LTBI) testing coverage, and yield. Results Pre and post update, 1,703 and 1,489 index patients were reported, 27,187 and 21,056 contacts were eligible for CI, 86% and 89% were tested for TB, and 0.70% and 0.73% were identified with active TB, respectively. Post update, the number of casual contacts invited per index patient decreased statistically significantly (RR = 0.88; 95% CI: 0.79–0.98), TB testing coverage increased (OR = 1.4; 95% CI: 1.2–1.7), and TB yield increased (OR = 2.0; 95% CI: 1.0–3.9). The total LTBI yield increased from 8.8% to 9.8%, with statistically significant increases for casual (OR = 1.2; 95% CI: 1.0–1.5) and community contacts (OR = 2.0; 95% CI: 1.6–3.2). The proportion of CIs appropriately scaled-up to community contacts increased statistically significantly (RR = 1.8; 95% CI: 1.3–2.6). Conclusion This study shows that promoting evidence-based CI guidelines strengthen the efficiency of CIs without jeopardising effectiveness. These findings support CI is an effective TB elimination intervention.
Intestinal epithelial tuft cell induction is negated by a murine helminth and its secreted products
Authors: Claire Drurey, Håvard T. Lindholm, Gillian Coakley, Marta Campillo Poveda, Stephan Löser, Rory Doolan, François Gerbe, Philippe Jay, Nicola Harris, Menno J. Oudhoff, Rick M. Maizels
Journal: The Journal of Experimental Medicine (2021)

Helminth parasites are adept manipulators of the immune system, using multiple strategies to evade the host type 2 response. In the intestinal niche, the epithelium is crucial for initiating type 2 immunity via tuft cells, which together with goblet cells expand dramatically in response to the type 2 cytokines IL-4 and IL-13. However, it is not known whether helminths modulate these epithelial cell populations. In vitro, using small intestinal organoids, we found that excretory/secretory products (HpES) from Heligmosomoides polygyrus blocked the effects of IL-4/13, inhibiting tuft and goblet cell gene expression and expansion, and inducing spheroid growth characteristic of fetal epithelium and homeostatic repair. Similar outcomes were seen in organoids exposed to parasite larvae. In vivo, H. polygyrus infection inhibited tuft cell responses to heterologous Nippostrongylus brasiliensis infection or succinate, and HpES also reduced succinate-stimulated tuft cell expansion. Our results demonstrate that helminth parasites reshape their intestinal environment in a novel strategy for undermining the host protective response.
Impact of Sociodemographic and Clinical Factors on the Survival of Patients with Acute Myeloid Leukemia: A Multicenter Experience in Colombia, on Behalf of Acho's Renehoc-Pethema Investigators
Authors: Claudia Lucia Sossa, Virginia Abello, Angela María Peña, Luis Antonio Salazar, Guillermo Quintero Vega, William Armando Mantilla Duran, Henry Idrobo, Jheremy Enrique Reyes Castellanos, Lina Gaviria, Carlos Daniel Bermudez Silva, Rigoberto Gomez, Mario Ernesto Correa, Paola Guerrero, Jose Sandoval-Sus, David Martínez-Cuadrón, Miguel A. Sanz, Pau Montesinos
Journal: Blood (2021)
Normal CMR Bi-Atrial and Biventricular Reference Values in Sickle Cell Disease Patients without Heart Damage
Authors: Alessia Pepe, Antonella Meloni, Elena Facchini, Antonella Quarta, Vincenzo Spadola, Angela Ermini, Aurelio Maggio, Antonino Vallone, Riccardo Righi, Massimiliano Missere, Vincenzo Positano, Laura Pistoia
Journal: Blood (2021)
A Prospective Study of Clonal Evolution in Follicular Lymphoma: Circulating Tumor DNA Correlates with Overall Tumor Burden and Fluctuates over Time without Therapy
Authors: Allison Distler, Rahul Lakhotia, James D. Phelan, Stefania Pittaluga, Christopher Melani, Jagan R. Muppidi, Jillian Simard, Amynah Pradhan, Amy Hillsman, Yandan Yang, Theresa Davies-Hill, Arthur L. Shaffer, Sarah Evans, Mark A. Ahlman, Allison P. Jacob, Alexander Bagaev, Mark Meerson, Ekaterina Postovalova, Olga Kudryashova, Nikita Kotlov, Nathan H. Fowler, Elaine S. Jaffe, Louis M. Staudt, Wyndham H. Wilson, Mark Roschewski
Journal: Blood (2021)
Does RAD21 Co-Mutation Have a Role in DNMT3A Mutated AML? Results of Harmony Alliance AML Database
Authors: Raúl Azibeiro Melchor, Alberto Hernández Sánchez, Teresa González, Marta Sobas, Javier Martinez Elicegui, Angela Villaverde Ramiro, Axel Benner, Eric Sträng, Castellani Gastone, Caroline A. Heckman, Ana Heredia Casanoves, Jurjen Versluis, María Abáigar, Laura Jamilis, Peter JM Valk, Klaus H. Metzeler, Rosa Ayala, Herve Dombret, Jorge Sierra, Claude Preudomme, Frederick Damm, Ken I Mills, Jiří Mayer, Christian Thiede, Maria Teresa Voso, Sergio Amadori, Guillermo Sanz, Frederico Calado, Konstanze Döhner, Verena I Gaidzik, Michael Heuser, Torsten Haferlach, Amin T. Turki, Dirk Reinhardt, Rubén Villoria Medina, Michel van Speybroeck, Renate Schulze-Rath, John E Butler, Brian J.P Huntly, Jesús M Hernández Rivas, Lars Bullinger, Hartmut Döhner, Gert J. Ossenkoppele
Journal: Blood (2021)
The Time Factor in Inhibition of Lymphoid-Tumor Development by Injection of Marrow Cell Suspensions into Irradiated C57BL Mice&lt;xref ref-type="fn" rid="fn1"&gt;2&lt;/xref&gt;&lt;xref ref-type="fn" rid="fn2"&gt;3&lt;/xref&gt;
Authors: Kaplan Hs, Moses Le, Brown Mb, Nagareda Cs, Hirsch Bb
Journal: JNCI Journal of the National Cancer Institute (1955)

Journal Article The Time Factor in Inhibition of Lymphoid-Tumor Development by Injection of Marrow Cell Suspensions into Irradiated C57BL Mice Get access Henry S. Kaplan, Henry S. Kaplan Departments of Radiology and Public Health, Stanford University School of Medicine, San Francisco, Calif. Search for other works by this author on: Oxford Academic PubMed Google Scholar Lincoln E. Moses, Lincoln E. Moses Departments of Radiology and Public Health, Stanford University School of Medicine, San Francisco, Calif. Search for other works by this author on: Oxford Academic PubMed Google Scholar Mary B. Brown, Mary B. Brown Departments of Radiology and Public Health, Stanford University School of Medicine, San Francisco, Calif. Search for other works by this author on: Oxford Academic PubMed Google Scholar C. Susan Nagareda, C. Susan Nagareda Departments of Radiology and Public Health, Stanford University School of Medicine, San Francisco, Calif. Search for other works by this author on: Oxford Academic PubMed Google Scholar Barbara B. Hirsch Barbara B. Hirsch Departments of Radiology and Public Health, Stanford University School of Medicine, San Francisco, Calif. Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 15, Issue 4, February 1955, Pages 975–979, https://doi.org/10.1093/jnci/15.4.975 Published: 01 February 1955 Article history Received: 27 October 1954 Published: 01 February 1955
Mobility and Muscle Strength in Recipients of Hematopoietic Cell Transplantation for Sickle Cell Disease: A Preliminary Report from Sickle Transplant Evaluation of Longterm and Late Effects Registry (STELLaR)
Authors: Anirudh Veludhandi, Tami D John, Nitya Bakshi, Staci D. Arnold, Monica Bhatia, Peter A. Lane, Lillian Meacham, Kirshma Khemani, Sonali Chaudhury, Festus Olusola Olowoselu, Kimberly A. Kasow, Matthew Hsieh, Allistair Abraham, Gregory M.T. Guilcher, Lakshmanan Krishnamurti
Journal: Blood (2021)
Impact of LMWH and Specific Factor Xa Inhibitors, Apixaban and Fondaparinux, on Cancer Cell Biology and Procoagulant Properties of Cancer Microenvironment
Authors: Huong Chi Mai Tran, Rania Amrane, Elisabeth Mbemba, Michele Sabbah, Ismail Elalamy, Jawed Fareed, Patrick Van Dreden, Grigorios T. Gerotziafas
Journal: Blood (2021)
Comparison of Liposomal Daunorubicin and Cytarabine Versus Cladribine and High-Dose Cytarabine-Based Induction Chemotherapy in Secondary Acute Myeloid Leukemia Patients (sAML) or Acute Myeloid Leukemia with Myelodysplastic Related Changes (AML-MRC)
Authors: Ariel Denson, Ryan J. Caddell, Katherine A. Richter, Jiannong Li, Kendra Sweet, Andrew T. Kuykendall, Eric Padron, Rami S. Komrokji, Jeffrey E. Lancet, Chetasi Talati, David A. Sallman
Journal: Blood (2021)
Azacytidine Treatment in Patients with Acute Myeloid Leukemia/High-Risk Myelodysplastic Syndrome: Day-Hospital Management Compared to Home Care Setting
Authors: Giulio Trapè, Gioia De Angelis, Marco Morucci, Michela Tarnani, Cinzia De Gregoris, Ambra Di Veroli, Valentina Panichi, Giuseppe Topini, Loredana Bassi, Raffaella Isidori, Monica Poscente, Vincenza Innocenti, Elisa Emanueli Cippitelli, Roberta Talucci, Silvia Bertelli, Alessandra Crocicchia, Annalisa Lippi, Giulia Pezzuti, Michela Fuschino, Raffaella Randi, Cristina Mastino, Silvia Ciambella, Gloria Pessina, Marco Montanaro, Roberto Latagliata
Journal: Blood (2021)
Barriers to and Results of Allogeneic Hematopoietic Transplantation for Adult Patients with Sickle Cell Disease: An Analysis of Referrals and Transplants Performed at a Single Center in the Era of Haploidentical Donor Use
Authors: Asad Bashey, Xu Zhang, H. Kent Holland, Lawrence E Morris, Scott R. Solomon, Melhem Solh
Journal: Blood (2021)
Tandem CD19/CD22 Dual Targets CAR-T Cells Therapy Obtains Superior CR Rate Than Single CD19 CAR-T Cells Infusion As Well As Sequential CD19 and CD22 CAR-T Cells Infusion for Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia Patients
Authors: Sining Liu, Xinyue Zhang, Haiping Dai, Qingya Cui, Wei Cui, Jia Yin, Zheng Li, Shengli Xue, Chunxiu Yang, Xiao Yang, Huiying Qiu, Miao Miao, Suning Chen, Zhengming Jin, Chengcheng Fu, Caixia Li, Aining Sun, Yue Han, Ying Wang, Lei Yu, Depei Wu, Xiaowen Tang
Journal: Blood (2021)
Amyloidosis Composite Response Score Incorporating the Depth of Organ Response
Authors: Nadine Abdallah, Eli Muchtar, Angela Dispenzieri, Morie A. Gertz, Prashant Kapoor, Martha Q. Lacy, Suzanne R. Hayman, Francis K. Buadi, Wilson I Gonsalves, Nelson Leung, David Dingli, Taxiarchis Kourelis, Rahma M Warsame, Moritz Binder, Robert A. Kyle, S. Vincent Rajkumar, Shaji Kumar
Journal: Blood (2021)
Standard of Care CAR-T Cell Therapy for Large B-Cell Lymphoma (LBCL): Does Bridging Efficacy Matter? a German GLA/DRST Real World Analysis
Authors: Wolfgang A Bethge, Peter Martus, Michael Schmitt, Udo Holtick, Peter Borchmann, Marion Subklewe, Kai Rejeski, Bastian von Tresckow, Francis A. Ayuk, Nicolaus Kroeger, Eva-Maria Wagner-Drouet, Gerald Wulf, Reinhard Marks, Olaf Penack, Ulf Schnetzke, Christian Koenecke, Malte Von Bonin, Matthias Stelljes, Bertram Glass, Claudia D. Baldus, Vladan Vucinic, Dimitrios Mougiakakos, Max Topp, Daniel Wolff, Roland Schroers, Simone Thomas, Dietrich W. Beelen, Claudia Lengerke, Peter Dreger
Journal: Blood (2021)
Donor Plasmacytoid Dendritic Cells Regulate GvHD in a VIP Dependent Manner in Allogeneic BMT Recipients
Authors: Jingru Zhu, Pankoj Kumar Das, Yitong Wang, Jingxia Li, Tamas Nagy, Khajan Ghandhi, Sruthi Ravindranathan, Cynthia R. Giver, Jian-Ming Li, Yiwen Li, Alina Ulezko Antonova, John D Roback, Shuhua Wang, Edmund K. Waller
Journal: Blood (2021)
Ferritin Levels Do Not Reflect the Severity of Iron Overload in Diamond Blackfan Anemia
Authors: Jonathan de Wilde, Birgit van Dooijeweert, Elise Huisman, Frans Smiers, Eduard J. Van Beers, Wouter Van Solinge, Edward E.S. Nieuwenhuis, Richard van Wijk, Marije Bartels
Journal: Blood (2021)
52 Characterization of the tumor microenvironment in melanoma using Multiplexed Ion Beam Imaging (MIBI)
Authors: Jason Ptacek, Matthew Vesely, David Rimm, Monirath Hav, Murat Aksoy, Ailey Crow, Jessica Finn
Journal: Journal for ImmunoTherapy of Cancer (2021)

Background The complexity of the tumor microenvironment (TME) necessitates the application of high-dimensional methods that can spatially resolve the phenotypic heterogeneity that exists within tumors. MIBI, which combines time-of-flight secondary ion mass spectrometry (ToF-SIMS) with metal labeled antibodies to simultaneously image 40+ proteins at subcellular spatial resolution, was used to classify cell populations and their expression of immunoregulatory proteins within 54 melanoma samples. Methods A tissue microarray (TMA) comprised of 0.6 mm FFPE melanoma cores was stained with a panel of 30 metal labeled antibodies. The tissue was imaged using MIBI and multi-step processing was performed to create images of the samples. Single cell segmentation enabled enumeration of 32 cell populations and quantitative analyses were performed of both immune checkpoint expression and the spatial relationships between cells of different types. Results Tumor cells and immune cells represented 62% (1.4% - 92.2%) and 24% (2.0% - 92.1%), respectively, of the segmented cells from the melanoma samples. Fibroblasts, lymphatics, and blood vessels were also present at varying densities. Within the immune compartment, M2 macrophages, M2 monocytes, and monocyte-derived dendritic cells (mDCs) were most abundant, representing 36.3% (4.9% - 79.3%), 7.0% (0.0% - 30.6%), and 9.8% (0.0% - 34.6%), respectively, of the total immune cell infiltrate. Rare populations such as myeloid-derived suppressor cells (MDSCs) and regulatory T cells were at greater than 100 cells/mm 2 in six samples and four samples, respectively. The presence of immune checkpoint markers (IDO-1, LAG3, PD-1, PD-L1, TIM-3) varied between populations and between samples. A minority of the samples showed expression of IDO-1 and PD-L1 on myeloid populations. Interestingly, among the myeloid subsets, M2 macrophages and monocyte-derived dendritic cells showed the most abundant PD-L1 expression. Although many samples had few T cell infiltrates, those that did showed expression of PD-1, LAG-3, and TIM-3 on T cell populations. Conclusions MIBI offers high-parameter tissue imaging, at sensitivity and resolution suited to understanding the complex tumor immune landscape, including the spatial relationships of immune and tumor cells and the expression of immunoregulatory proteins. Datasets that quantify population densities and immune checkpoint expression levels across tumor samples, such as the present one, can be used to test for associations to clinical variables and further understand the TME at the cellular level.
FLT3-Mutated Acute Myeloid Leukemia Using a Novel Regimen of Gemtuzumab Ozogamicin and Midostaurin in Combination with Standard Cytarabine and Daunorubicin Induction Therapy
Authors: Uma Borate, Andy Kaempf, Jessica Minnier, Shikha Misra, Shaun Goodyear, Gabrielle Meyers, Jennifer N. Saultz, Elie Traer, Ronan Swords, Rachel J. Cook, Sammantha Avaylon, Melissa Mackey, Brianna Norris, Roland B. Walter
Journal: Blood (2021)
Abstract 9037: Effectiveness of Online CME at Improving Cardiologists’ and Pcps’ Knowledge and Confidence Related to Diagnosis and Treatment of Hereditary Transthyretin Amyloidosis
Authors: Margaret Harris, Alison O'Connor, George Boutsalis
Journal: Circulation (2021)

Introduction: Despite advances in hATTR management, patients experience delays in diagnosis and initiation of targeted treatment, resulting in suboptimal care. We sought to determine if online continuing medical education (CME) could improve the knowledge and confidence of cardiologists and primary care physicians (PCPs) related to diagnostic features of hATTR and targeted treatment strategies for hATTR. Methods: This CME intervention comprised of a 30-minute online video-based discussion between 2 expert faculty. Responses to 3 multiple-choice, knowledge questions and 1 self-efficacy, 5-point Likert scale confidence question were analyzed using a repeated pairs pre-/post-assessment study design. A chi-square test (P &lt;.05 is considered significant) assessed pre- to post-activity change. The activity launched March 26, 2020 and data were collected through June 10, 2020. Results: In total, 144 cardiologists and 384 PCPs were included in the study. Overall, there were knowledge and confidence improvements seen among all groups from pre- to post-assessment: • 8% of cardiologists (P=ns) and 16% of PCPs (P&lt;.0001) improved at identifying diagnostic features of hATTR • 23% of cardiologists (p&lt;.001) and 27% of PCPs (p&lt;.001) improved at selecting MOA of current treatment approaches targeting TTR in patients with hATTR • 40% of cardiologists and 56% of PCPs had a measurable increase in confidence in recognizing early diagnostic features in patients with hATTR Continued educational gaps: • 12% of cardiologists and 14% of PCPs failed to select diagnostic features of hATTR • 59% of cardiologists and 58% of PCPs failed to select MOA of current treatment approaches targeting TTR in patients with hATTR Conclusions: This study demonstrates the success of online CME on improving knowledge and confidence of cardiologists and PCPs related to recognition of diagnostic features in patients with hATTR. Continued gaps were identified for future educational targets.
Diffuse Large B-Cell Lymphoma (DLBCL) Patients with Late Relapses Who Are Transplant-Eligible Have Excellent Outcomes and May Represent Unique Biology
Authors: Henry S. Ngu, Laura K Hilton, Judith Anula Rodrigo, Diego Villa, Alina S. Gerrie, Kevin Song, Pedro Farinha, Graham W. Slack, Kerry J. Savage, David W. Scott, Laurie H. Sehn
Journal: Blood (2021)
Diagnostic Utility of Multimodal Genomic Profiling for Molecular Classification and MRD Assessment in Adult B-Cell Acute Lymphoblastic Leukemia
Authors: Georgina L Ryland, Ashish Bajel, Michael Dickinson, Paul G Ekert, Oliver Hofmann, Maarten IJzerman, Ashley P Ng, Alicia Oshlack, Breon Schmidt, Ing S Tiong, Martin Vu, David Alan Westerman, Sean Grimmond, Piers Blombery
Journal: Blood (2021)
Proteomic Profiling Based Classification of CLL Provides Prognostication for Modern Therapy and Identifies Novel Therapeutic Targets
Authors: Ti'ara L. Griffen, Fieke W Hoff, Yihua Qiu, James W Lillard, Alessandra Ferrajoli, Philip A. Thompson, Endurance Toro, Kevin Ruiz, Jan A. Burger, William G. Wierda, Steven M. Kornblau
Journal: Blood (2021)
Administration of Granulocyte Colony-Stimulating Factor Post-Transplant Impedes Engraftment of CRISPR-Cas9 Edited Long-Term Repopulating Hematopoietic Stem and Progenitor Cells
Authors: Daisuke Araki, Christi Salisbury-Ruf, Waleed Hakami, Keyvan Keyvanfar, Richard H. Smith, Andre Larochelle
Journal: Blood (2021)
Cardiac Events in Patients with Acute Myeloid Leukemia Treated with Venetoclax in Combination with Hypomethylating Agents
Authors: Isla M. Johnson, Evandro D. Bezerra, Faiqa Farrukh, Kristen McCullough, Aref Al-Kali, Hassan B. Alkhateeb, Kebede H. Begna, Mark R. Litzow, William J Hogan, Mithun V. Shah, Mrinal M. Patnaik, Ayalew Tefferi, Naseema Gangat
Journal: Blood (2021)
Phase 2 Study of Zanubrutinib in BTK Inhibitor-Intolerant Patients (Pts) with Relapsed/Refractory B-Cell Malignancies
Authors: Mazyar Shadman, Ian W. Flinn, Moshe Y. Levy, Ryan Porter, John M. Burke, Jennifer L. Cultrera, Jamal Misleh, Syed F. Zafar, Benjamin Freeman, Subramanya S. Rao, Habte Yimer, Arvind Chaudhry, Mitul D. Gandhi, Troy H. Guthrie, Edwin Kingsley, Praveen K. Tumula, Sudhir Manda, Dih-Yih Chen, Aileen Cohen, Kunthel By, Linlin Xu, Ye Liu, Jeff P. Sharman
Journal: Blood (2021)
MRI-based (MAST) score accurately identifies patients with NASH and significant fibrosis
Authors: Mazen Noureddin, Emily Truong, Jeffrey A. Gornbein, Rola Saouaf, Maha Guindi, Tsuyoshi Todo, Nabil Noureddin, Ju Dong Yang, Stephen A. Harrison, Naim Alkhouri
Journal: Journal of Hepatology (2021)
Whole Genome Sequencing Identifies Microdeletions Affecting <i>TET2</i> and <i>RUNX1</i> with Clinical Impact in Myeloid Malignancies
Authors: Constance Baer, Wencke Walter, Stephan Hutter, Niroshan Nadarajah, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach, Manja Meggendorfer
Journal: Blood (2021)