tbuckley/cabot-search huggingface dataset:
Gasdermin D in pyroptosis
Authors: Brandon E. Burdette, Ashley N. Esparza, Hua Zhu, Shanzhi Wang
Journal: Acta Pharmaceutica Sinica B (2021)

Pyroptosis is the process of inflammatory cell death. The primary function of pyroptosis is to induce strong inflammatory responses that defend the host against microbe infection. Excessive pyroptosis, however, leads to several inflammatory diseases, including sepsis and autoimmune disorders. Pyroptosis can be canonical or noncanonical. Upon microbe infection, the canonical pathway responds to pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs), while the noncanonical pathway responds to intracellular lipopolysaccharides (LPS) of Gram-negative bacteria. The last step of pyroptosis requires the cleavage of gasdermin D (GsdmD) at D275 (numbering after human GSDMD) into N- and C-termini by caspase 1 in the canonical pathway and caspase 4/5/11 (caspase 4/5 in humans, caspase 11 in mice) in the noncanonical pathway. Upon cleavage, the N-terminus of GsdmD (GsdmD-N) forms a transmembrane pore that releases cytokines such as IL-1β and IL-18 and disturbs the regulation of ions and water, eventually resulting in strong inflammation and cell death. Since GsdmD is the effector of pyroptosis, promising inhibitors of GsdmD have been developed for inflammatory diseases. This review will focus on the roles of GsdmD during pyroptosis and in diseases.
CATHETER ABLATION IS SUPERIOR TO ANTIARRHYTHMIC DRUGS AS FIRST-LINE TREATMENT FOR ATRIAL FIBRILLATION: A SYSTEMATIC REVIEW AND META-ANALYSIS
Authors: Rhanderson Cardoso, Gustavo B. Justino, Leonardo Knijnik, Leticia B.C. Soares, Luana M.F. Sanchez, Fabrissio P. Graffunder, Andre d'Avila
Journal: Journal of the American College of Cardiology (2021)
High-risk Human Papillomavirus Testing for Cervical Cancer Screening
Authors: Stephanie P. S. Totten, Joan Miguel Romero
Journal: JAMA Oncology (2021)

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AORTIC STENOSIS IN PATIENTS WITH SYSTEMIC SCLEROSIS: PREVALENCE, RISK FACTORS AND CLINICAL OUTCOMES
Authors: Sarah Khan, Julie Windholz, Keegan Olmstead, Christine Zhou, Yousef Ahmad, Patricio Alzamora-Schmatz, David Harris, Jose Gomez-Arroyo, Jean Elwing
Journal: Journal of the American College of Cardiology (2021)
PARTICIPATION RATES AND PATIENT CHARACTERISTICS AMONG PATIENTS ENROLLED IN THE KAISER PERMANENTE SOUTHERN CALIFORNIA HOME-BASED CARDIAC REHABILITATION PROGRAM DURING COVID-19: INITIAL RESULTS
Authors: Columbus Batiste, Chileshe Price, Timothy Cotter, Debbie Lahti, Christine Ruygrok, Nancy Gin, Tad Funahashi
Journal: Journal of the American College of Cardiology (2021)
SOCIOECONOMIC STATUS AND HYPERTENSION IN SOUTH CENTRAL UGANDA
Authors: Aishat Mustapha, Joseph Ssekasanvu, Ivy Chen, Kate Grabowski, Robert Ssekubugu, Godfrey Kigozi, Steven J. Reynolds, Ronald H. Gray, Maria J. Wawer, Joseph Kagaayi, Larry W. Chang, Wendy S. Post
Journal: Journal of the American College of Cardiology (2021)
Abstract 18293: Predicting In-Hospital Mortality in Acute Type B Aortic Dissection: Evidences From IRAD
Authors: Jip L Tolenaar, William Froehlich, Frederik H Jonker, Gilbert R Upchurch, Vincenzo Rampoldi, Thomas T Tsai, Eduaro Bossone, Arturo Evangelista, Patrick O’Gara, Linda Pape, Daniel G Montgomery, Eric M Isselbacher, Christoph A Nienaber, Kim A Eagle, Santi Trimarchi
Journal: Circulation (2013)

Introduction: The outcome of acute type B aortic dissection (ABAD) patients is strongly related to the clinical presentation. The purpose of this study was to investigate predictors for mortality among patients presenting ABAD and to create a predictive model to estimate individual risk of in-hospital mortality using the International Registry of Acute Aortic dissection (IRAD). Methods: All ABAD patients enrolled in IRAD between 1996 and 2013 were included for analysis. Multivariate logistic regression analysis was used to investigate predictors of in-hospital mortality. Significant risk factors for in-hospital death were used to develop a prediction model. Results: A total of 1034 ABAD patients were included for analysis (673 male; mean age 63.5 ± 14.0), with an overall in-hospital mortality of 10.4%. In multivariate analysis, the following variables at admission were independently associated with increased in-hospital mortality: increasing age (OR 1.03, 95%CI 1.00-1.06, p=.044), hypotension/shock (OR 6.43, 95%CI 2.88-18.98), periaortic hematoma (OR 3.06, 95%CI 1.38-6.78, p=.006), descending diameter &gt;5.5cm, (OR 6.04, 95%CI 2.87-12.73, p&lt;.001), mesenteric ischemia (OR 9.03, 95%CI 3.49-23.38, p&lt;.001), acute renal failure (OR 3.61, 95%CI 1.68-7.75) and limb ischemia (OR 3.02, 95%CI 1.05-8.68, p=.040). Based on these multivariate results, a reliable and simple bedside risk prediction tool was developed. Conclusion: The clinical presentation of ABAD is heterogeneous and strongly predicts in-hospital outcome. We present a simple prediction model using variables that are independently associated with in-hospital mortality in ABAD patients. This model could be used to assist physicians in their choice of management and for informing patients and their families.
線維要素の調整可能な比率を持つ異型3D膵臓癌モデル【JST・京大機械翻訳】
Authors: Y Tanaka Hiroyoshi, Kurihara Tsuyoshi, Nakazawa Takuya, Matsusaki Michiya, Masamune Atsushi, R Kano Mitsunobu
Journal: Biomaterials (2020)
COMPARISON OF LARGE-BORE ACCESS CLOSURE IN TRANSCATHETER AORTIC VALVE REPLACEMENT USING MANTA AND PERCLOSE - A REAL-WORLD EXPERIENCE
Authors: Giorgio Medranda, Cheng Zhang, Brian Case, Charan Yerasi, Brian Forrestal, Chava Chezar-Azzerad, Toby Rogers, Itsik Ben-Dor, Lowell Satler, Ron Waksman
Journal: Journal of the American College of Cardiology (2021)
OUTCOMES OF CARDIOGENIC SHOCK IN PATIENTS WITH AUTOIMMUNE DISEASES
Authors: Mohammad Al-Akchar, Venkata Missula, Yasser Al-Khadra, Khalid Sawalha, Tharani Sundararajan, Cameron Koester, Mukul Bhattarai, Mohsin Salih, Youssef Chami, Tony DeMartini, Abdul Moiz Hafiz
Journal: Journal of the American College of Cardiology (2021)
Interaction between Genetic Risk Scores for reduced pulmonary function and smoking, asthma and endotoxin
Authors: Sinjini Sikdar, Annah B Wyss, Mi Kyeong Lee, Thanh T Hoang, Marie Richards, Laura E Beane Freeman, Christine Parks, Peter S Thorne, John L Hankinson, David M Umbach, Alison Motsinger-Reif, Stephanie J London
Journal: Thorax (2021)

Rationale Genome-wide association studies (GWASs) have identified numerous loci associated with lower pulmonary function. Pulmonary function is strongly related to smoking and has also been associated with asthma and dust endotoxin. At the individual SNP level, genome-wide analyses of pulmonary function have not identified appreciable evidence for gene by environment interactions. Genetic Risk Scores (GRSs) may enhance power to identify gene–environment interactions, but studies are few. Methods We analysed 2844 individuals of European ancestry with 1000 Genomes imputed GWAS data from a case–control study of adult asthma nested within a US agricultural cohort. Pulmonary function traits were FEV 1 , FVC and FEV 1 /FVC. Using data from a recent large meta-analysis of GWAS, we constructed a weighted GRS for each trait by combining the top (p value&lt;5×10 −9 ) genetic variants, after clumping based on distance (±250 kb) and linkage disequilibrium (r 2 =0.5). We used linear regression, adjusting for relevant covariates, to estimate associations of each trait with its GRS and to assess interactions. Results Each trait was highly significantly associated with its GRS (all three p values&lt;8.9×10 −8 ). The inverse association of the GRS with FEV 1 /FVC was stronger for current smokers (p interaction =0.017) or former smokers (p interaction =0.064) when compared with never smokers and among asthmatics compared with non-asthmatics (p interaction =0.053). No significant interactions were observed between any GRS and house dust endotoxin. Conclusions Evaluation of interactions using GRSs supports a greater impact of increased genetic susceptibility on reduced pulmonary function in the presence of smoking or asthma.
An orally available PD-1/PD-L1 blocking peptide OPBP-1-loaded trimethyl chitosan hydrogel for cancer immunotherapy
Authors: Wanqiong Li, Xueqin Zhu, Xiuman Zhou, Xiaoxi Wang, Wenjie Zhai, Bingyu Li, Jiangfeng Du, Guodong Li, Xinghua Sui, Yahong Wu, Mingxia Zhai, Yuanming Qi, Guanyu Chen, Yanfeng Gao
Journal: Journal of Controlled Release (2021)
Allogeneic hematopoietic cell transplantation with cord blood versus mismatched unrelated donor with post-transplant cyclophosphamide in acute myeloid leukemia
Authors: Bhagirathbhai Dholaria, Myriam Labopin, Jaime Sanz, Annalisa Ruggeri, Jan Cornelissen, Hélène Labussière-Wallet, Didier Blaise, Edouard Forcade, Patrice Chevallier, Anna Grassi, Ludmila Zubarovskaya, Jürgen Kuball, Patrice Ceballos, Fabio Ciceri, Frederic Baron, Bipin N. Savani, Arnon Nagler, Mohamad Mohty
Journal: Journal of Hematology & Oncology (2021)

Abstract Background Allogeneic hematopoietic cell transplantation (allo-HCT) using a mismatched unrelated donor (MMUD) and cord blood transplantation (CBT) are valid alternatives for patients without a fully human leukocyte antigen (HLA)-matched donor. Here, we compared the allo-HCT outcomes of CBT versus single-allele-mismatched MMUD allo-HCT with post-transplant cyclophosphamide (PTCy) in acute myeloid leukemia. Methods Patients who underwent a first CBT without PTCy ( N = 902) or allo-HCT from a (HLA 9/10) MMUD with PTCy ( N = 280) were included in the study. A multivariate regression analysis was performed for the whole population. A matched-pair analysis was carried out by propensity score-based 1:1 matching of patients (177 pairs) with known cytogenetic risk. Results The incidence of grade II–IV and grade III–IV acute graft-versus-host disease (GVHD) at 6 months was 36% versus 32% ( p = 0.07) and 15% versus 11% ( p = 0.16) for CBT and MMUD cohorts, respectively. CBT was associated with a higher incidence of graft failure (11% vs. 4%, p &lt; 0.01) and higher 2-year non-relapse mortality (NRM) (30% vs. 16%, p &lt; 0.01) compared to MMUD. In the multivariate analysis, CBT was associated with a higher risk of, NRM (HR = 2.09, 95% CI 1.46–2.99, p &lt; 0.0001), and relapse (HR = 1.35, 95% CI 1–1.83, p = 0.05), which resulted in worse leukemia-free survival (LFS) (HR = 1.68, 95% CI 1.34–2.12, p &lt; 0.0001), overall survival (OS) (HR = 1.7, 95% CI 1.33–2.17, p &lt; 0.0001), and GVHD-free, relapse-free survival (GRFS) (HR = 1.49, 95% CI 1.21–1.83, p &lt; 0.0001) compared to MMUD. The risk of grade II–IV acute GVHD ( p = 0.052) and chronic GVHD ( p = 0.69) did not differ significantly between the cohorts. These results were confirmed in a matched-pair analysis. Conclusions CBT was associated with lower LFS, OS, and GRFS due to higher NRM, compared to MMUD allo-HCT with PTCy. In the absence of a fully matched donor, 9/10 MMUD with PTCy may be preferred over CBT.
A Step Forward in Using Artificial Intelligence to Identify Serious Retinopathy of Prematurity—A Start With a Long Road Ahead
Authors: Graham E. Quinn
Journal: JAMA Network Open (2021)

Ji Wang, PhD; Jie Ji, MEng; Mingzhi Zhang, MD; Jian-Wei Lin, MEng; Guihua Zhang, MD, PhD; Weifen Gong, MD; Ling-Ping Cen, MD, PhD; Yamei Lu, MD; Xuelin Huang, MD; Dingguo Huang, MD; Taiping Li, MD; Tsz Kin Ng, PhD; Chi Pui Pang, DPhil
Comparison of Outcomes Following Allogeneic HCT for Adverse Cytogenetic/Molecular Risk AML Using T-Replete Haploidentical Donors to Optimally Matched Related and Unrelated Donors
Authors: Asad Bashey, Xu Zhang, Stacey Brown, Katelin C Jackson, Lawrence E Morris, H. Kent Holland, Melhem M Solh, Scott R Solomon
Journal: Blood (2017)
AORTIC ROOT THROMBOSIS IN PATIENTS WITH HEARTMATE 3 LEFT VENTRICULAR ASSIST DEVICES
Authors: Dylan P. Marshall, Matthew Carey, Ronald Laracuente, Kevin Clerkin, Amirali Masoumi, Yuji Kaku, Jayant Raikhelkar, Jan Griffin, Jay S. Leb, Sneha Jain, Joseph E. Sanchez, Hiroo Takayama, Melana Yuzefpolskaya, Paolo Colombo, Koji Takeda, Gabriel Sayer, Yoshifumi Naka, Nir Uriel, Veli Topkara, Justin Fried
Journal: Journal of the American College of Cardiology (2021)
MYOCARDIAL TISSUE CHARACTERIZATION USING NATIVE T1 TIME PREDICTS THE OCCURRENCE OF ADVERSE EVENTS IN PATIENTS WITH CHRONIC KIDNEY DISEASE AND SEVERE AORTIC STENOSIS
Authors: Jay Ramchand, Jean-Pierre Iskandar, Rishi Puri, Michael Chetrit, Louise Burrell, Amar Krishnaswamy, Brian Griffin, James Yun, Scott Flamm, Samir Kapadia, Deborah Kwon, Serge Harb
Journal: Journal of the American College of Cardiology (2021)
IDENTIFYING A RARE BUT LETHAL COMPLICATION OF ACUTE MYOCARDIAL INFARCTION
Authors: Zeel Patel, Brian Henstenburg, David Egeler, Preysi Patel, Desire Guthier, Akhil Kher, Lekha Racharla, Rahul Gupta, Paul Secheresiu, Tarick Sheikh, Bilal Saqi, Umair Tariq, Sagar Vadhar, Apurva Vyas
Journal: Journal of the American College of Cardiology (2021)
THE IMPACT OF PERICORONARY ADIPOSE TISSUE ATTENUATION ON GLOBAL CORONARY FLOW RESERVE IN PATIENTS WITH STABLE CORONARY ARTERY DISEASE
Authors: Yoshihisa Kanaji, Tomoyo Sugiyama, Masahiro Hoshino, Toru Misawa, Tatsuhiro Nagamine, Yumi Yasui, Kai Nogami, Hiroki Ueno, Masahiro Hada, Masao Yamaguchi, Taishi Yonetsu, Tsunekazu Kakuta
Journal: Journal of the American College of Cardiology (2021)
CLINICAL IMPACT AND PREDICTORS OF TROPONIN ELEVATION IN PATIENTS WITH COVID-19
Authors: Brian Case, Charan Yerasi, Brian Forrestal, Corey Shea, Hank Rappaport, Giorgio Medranda, Cheng Zhang, Lowell Satler, Itsik Ben-Dor, Hayder Hashim, Toby Rogers, Ron Waksman
Journal: Journal of the American College of Cardiology (2021)
Willpower is overrated
Authors: Michael Inzlicht, Malte Friese
Journal: Behavioral and Brain Sciences (2021)

Abstract Any analysis of self-regulation that focuses solely on willpower in conflict-laden situations is insufficient. Research makes clear that the best way to reach one's goal is not to resist temptations but to avoid temptations before they arrive; it further suggests that willpower is fragile and not to be relied on; and that the best self-regulators engage in willpower remarkably seldom.
A case of pancreatic schwannoma with a focus on contrast-enhanced endoscopic ultrasonography
Authors: Takao Iemoto, Ayaka Sasaki, Tsuyoshi Sanuki, Yuki Yamamoto
Journal: Endoscopy (2021)

A schwannoma is a benign peripheral nerve sheath tumor originating from Schwann cells [1]. Although schwannomas appear as well-demarcated hypoechoic masses on endoscopic ultrasonography (EUS) [2], there are few reports on pancreatic schwannoma diagnosed by EUS. A pancreatic schwannoma is difficult to diagnose preoperatively because of the lack of established imaging characteristics. We present a case of pancreatic schwannoma that was diagnosed by contrast-enhanced EUS and endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA).
STAG2 mutations alter CTCF-anchored loop extrusion, reduce cis-regulatory interactions and EWSR1-FLI1 activity in Ewing sarcoma
Authors: Didier Surdez, Sakina Zaidi, Sandrine Grossetête, Karine Laud-Duval, Anna Sole Ferre, Lieke Mous, Thomas Vourc'h, Franck Tirode, Gaelle Pierron, Virginie Raynal, Sylvain Baulande, Erika Brunet, Véronique Hill, Olivier Delattre
Journal: Cancer Cell (2021)
Smoking Treatment: A Report Card on Progress and Challenges
Authors: Timothy B. Baker, Danielle E. McCarthy
Journal: Annual Review of Clinical Psychology (2021)

The impact of tobacco smoking treatment is determined by its reach into the smoking population and the effectiveness of its interventions. This review evaluates the reach and effectiveness of pharmacotherapy and psychosocial interventions for smoking. Historically, the reach of smoking treatment has been low, and therefore its impact has been limited, but new reach strategies such as digital interventions and health care system changes offer great promise. Pharmacotherapy tends to be more effective than psychosocial intervention when used clinically, and newer pharmacotherapy strategies hold great promise of further enhancing effectiveness. However, new approaches are needed to advance psychosocial interventions; progress has stagnated because research and dissemination efforts have focused too narrowly on skill training despite evidence that its core content may be inconsequential and the fact that its mechanisms are either unknown or inconsistent with supporting theory. Identifying effective psychosocial content and its mechanisms of action could greatly enhance the effectiveness of counseling, digital, and web interventions.
Understanding Risk for Newborns Born to SARS-CoV-2–Positive Mothers
Authors: Dani Dumitriu, Cynthia Gyamfi-Bannerman
Journal: JAMA (2021)

Mikael Norman, MD; Lars Navér, MD; Jonas Söderling, PhD; Mia Ahlberg, PhD; Helena Hervius Askling, MD; Bernice Aronsson, MD; Emma Byström, MSc; Jerker Jonsson, MD; Verena Sengpiel, MD; Jonas F. Ludvigsson, MD; Stellan Håkansson, MD; Olof Stephansson, MD
Opportunities to prevent children dying from asthma are being missed, says safety watchdog
Authors: Clare Dyer
Journal: BMJ (2021)

Children are dying preventable deaths because opportunities are being missed to recognise asthma as a chronic and life threatening condition, a national investigation by the Healthcare Service Investigation Branch (HSIB) has concluded.1

The investigation was launched after a five year old boy suffered a near fatal asthma attack and spent seven weeks in hospital, including 13 days in intensive care. The boy, who was born prematurely, had been a frequent attender at hospital, as an outpatient or inpatient or for emergency care.

The HSIB also looked at three preventable fatal cases in which coroners had made reports to prevent future deaths. “All three cases highlighted missed opportunities to recognise asthma as a …
BASELINE DEMOGRAPHICS AND CLINICAL OUTCOMES IN SPONTANEOUS CORONARY ARTERY DISSECTION PATIENTS WITH AND WITHOUT FIBROMUSCULAR DYSPLASIA
Authors: Cameron McAlister, Mesfer Alfadhel, Rohit Samuel, Andrew Starovoytov, Tejana Grewal, Johandra Argote Parolis, Eve Aymong, Jacqueline Saw
Journal: Journal of the American College of Cardiology (2021)
Mitral Surgery After Transcatheter Edge-to-Edge Repair
Authors: Joanna Chikwe, Patrick O'Gara, Stephen Fremes, Thoralf M Sundt, Robert H Habib, James Gammie, Mario Gaudino, Vinay Badhwar, Marc Gillinov, Michael Acker, Georgina Rowe, George Gill, Andrew B Goldstone, Thomas Schwann, Annetine Gelijns, Alfredo Trento, Michael Mack, David H Adams
Journal: Journal of the American College of Cardiology (2021)
PREVALENT STATIN USE IN RELATION TO BLOOD CHOLESTEROL TESTING AMONG US ADULTS WITH ATHEROSCLEROTIC CARDIOVASCULAR DISEASE: A POPULATION-BASED COHORT STUDY
Authors: Usman Baber, Omar Baber, Isma Javed, Usman Bhatti, Beau Hawkins, Paul Muntner
Journal: Journal of the American College of Cardiology (2021)
Discovery of a subtype-selective, covalent inhibitor against palmitoylation pocket of TEAD3
Authors: Tian Lu, Yong Li, Wenchao Lu, TWGM Spitters, Xueyu Fang, Jun Wang, Simian Cai, Jing Gao, Yanting Zhou, Zhe Duan, Huan Xiong, Liping Liu, Qi Li, Hualiang Jiang, Kaixian Chen, Hu Zhou, Hua Lin, Huijin Feng, Bing Zhou, Christopher L. Antos, Cheng Luo
Journal: Acta Pharmaceutica Sinica B (2021)

The TEA domain (TEAD) family proteins (TEAD1‒4) are essential transcription factors that control cell differentiation and organ size in the Hippo pathway. Although the sequences and structures of TEAD family proteins are highly conserved, each TEAD isoform has unique physiological and pathological functions. Therefore, the development and discovery of subtype selective inhibitors for TEAD protein will provide important chemical probes for the TEAD-related function studies in development and diseases. Here, we identified a novel TEAD1/3 covalent inhibitor (DC-TEADin1072) with biochemical IC50 values of 0.61 ± 0.02 and 0.58 ± 0.12 μmol/L against TEAD1 and TEAD3, respectively. Further chemical optimization based on DC-TEAD in 1072 yielded a selective TEAD3 inhibitor DC-TEAD3in03 with the IC50 value of 0.16 ± 0.03 μmol/L, which shows 100-fold selectivity over other TEAD isoforms in activity-based protein profiling (ABPP) assays. In cells, DC-TEAD3in03 showed selective inhibitory effect on TEAD3 in GAL4-TEAD (1-4) reporter assays with the IC50 value of 1.15 μmol/L. When administered to zebrafish juveniles, experiments showed that DC-TEAD3in03 reduced the growth rate of zebrafish caudal fins, indicating the importance of TEAD3 activity in controlling proportional growth of vertebrate appendages.
CARDIOVASCULAR PROTEOMICS PROFILES IN REPLACEMENT AND INTERSTITIAL MYOCARDIAL FIBROSIS: THE MULTI-ETHNIC STUDY OF ATHEROSCLEROSIS
Authors: Hooman Bakhshi, Pramita Bagchi, Jiayang Sun, Stephen Seliger, Guoqing Diao, Bharath Ambale Venkatesh, Vinithra Varadarajan, Joao Lima, Christopher DeFilippi
Journal: Journal of the American College of Cardiology (2021)
FIVE-YEAR SAFETY ANALYSIS OF SACUBITRIL/VALSARTAN: A COMPARATIVE ANALYSIS OF ADVERSE EVENTS IN RANDOMIZED CLINICAL TRIALS AND REAL-WORLD PHARMACOVIGILANCE
Authors: Yee Soo Kim, Simerjeet Brar, Natalie D’Albo, Sachin Shah, Sarju Ganatra, Sourbha Dani
Journal: Journal of the American College of Cardiology (2021)
FULMINANT MYOCARDITIS IN COVID-19 WITH RAPID RECOVERY OF SYSTOLIC FUNCTION
Authors: Avery Calhoun, Yetunde Fatade, Mariana Garcia, Franck Azobou Tonleu, Tuoyo Mene-Afejuku, An Young, Marc Thames, Minh Nguyen, Modele Ogunniyi
Journal: Journal of the American College of Cardiology (2021)
ELECTRICAL REVERSE REMODELING WITH SACUBITRIL-VALSARTAN FOR HEART FAILURE: REDUCTION IN QRS 3D VOLTAGE TIME INTERVAL (3D QRS AREA)
Authors: Nikhil Parimi, Uzair Mahmood, Anas Abudan, Farhad Sami, Christopher Harvey, Colton Schwarz, Michael Pierpoline, Andrew Sauer, Bhanu Gupta, Madhu Reddy, Seth Sheldon, Amit Noheria
Journal: Journal of the American College of Cardiology (2021)
Abstract 18353: Vascular Effects of Endothelial Specific alpha1AMPK Deletion During Exercise Training
Authors: Thomas Jansen, Swenja Kroeller-Schoen, Thomas Münzel, Eberhard Schulz
Journal: Circulation (2017)

Introduction: Cardiovascular disease represents an ongoing worldwide health problem with high mortality due to myocardial infarction, heart failure and stroke. In this respect, disease prevention i...
EARLY AND LATE RECURRENT CARDIOVASCULAR RISK IN PATIENTS WITH RECENT ACUTE CORONARY SYNDROME - META-ANALYSIS AND IMPLICATIONS IN TRIAL DESIGN
Authors: Gerald Chi, Jane J. Lee, Syed Hassan A. Kazmi, Clara Fitzgerald, Sahar Memar Montazerin, Arzu Kalayci, Serge Korjian, Adam T. Phillips, Mark Heise, Lawrence Deckelbaum, Peter Libby, Deepak L. Bhatt, C. Michael Gibson
Journal: Journal of the American College of Cardiology (2021)