tbuckley/cabot-search huggingface dataset:
IL-23 reshapes kidney resident cell metabolism and promotes local kidney inflammation
Authors: Hao Li, Maria G. Tsokos, Rhea Bhargava, Iannis E. Adamopoulos, Hanni Menn-Josephy, Isaac E. Stillman, Philip Rosenstiel, Jarrat Jordan, George C. Tsokos
Journal: Journal of Clinical Investigation (2021)

Interstitial kidney inflammation is present in various nephritides in which serum interleukin 23 (IL-23) is elevated. Here we showed that murine and human renal tubular epithelial cells (TECs) expressing the IL-23 receptor (IL-23R) responded to IL-23 by inducing intracellular calcium flux, enhancing glycolysis, and upregulating calcium/calmodulin kinase IV (CaMK4), which resulted in suppression of the expression of the arginine-degrading enzyme arginase 1 (ARG1), thus increasing in situ levels of free L-arginine. Limited availability of arginine suppressed the ability of infiltrating T cells to proliferate and produce inflammatory cytokines. TECs from humans and mice with nephritis expressed increased levels of IL-23R and CaMK4 but reduced levels of ARG1. TEC-specific deletion of Il23r or Camk4 suppressed inflammation, whereas deletion of Arg1 exacerbated inflammation in different murine disease models. Finally, TEC-specific delivery of a CaMK4 inhibitor specifically curbed renal inflammation in lupus-prone mice without affecting systemic inflammation. Our data offer the first evidence to our knowledge of the immunosuppressive capacity of TECs through a mechanism that involves competitive uptake of arginine and signify the importance of modulation of an inflammatory cytokine in the function of nonlymphoid cells, which leads to the establishment of an inflammatory microenvironment. New approaches to treat kidney inflammation should consider restoring the immunosuppressive capacity of TECs.
DOES PRE-TREATMENT WITH AN ANTIARRHYTHMIC MEDICATION FACILITATE MAINTENANCE OF SINUS RHYTHM FOLLOWING CRYOBALLOON PULMONARY VEIN ISOLATION IN PATIENTS WITH PERSISTENT ATRIAL FIBRILLATION?
Authors: Dan Laurentiu Musat, Nicolle Milstein, Matthew Saberito, Bhatt Advay, Mohammadali Habibi, Tina Sichrovsky, Mark Preminger, Richard Shaw, Suneet Mittal
Journal: Journal of the American College of Cardiology (2021)
ASSOCIATION OF PERCUTANEOUS LEFT ATRIAL APPENDAGE OCCLUSION WITH STROKE, BLEEDING AND MORTALITY IN COMPARISON TO NOACS AMONG PATIENTS WITH AF
Authors: Xiaoxi Yao, Holly Van Houten, Harlan Krumholz, David Kent, Nilay Shah, Neena Abraham, Jonathan Graff-Radford, Mohamad Alkhouli, Henry Henk, LIndsey Sangaralingham, Bernard Gersh, Paul Friedman, David Holmes, Peter Noseworthy
Journal: Journal of the American College of Cardiology (2021)
THE ASSOCIATION BETWEEN RESTLESS LEGS SYNDROME AND SOLUBLE UROKINASE-TYPE PLASMINOGEN ACTIVATOR RECEPTOR - A CONNECTION TO CARDIOVASCULAR DISEASE
Authors: Nishant Vatsa, Zakaria Almuwaqqat, Jeong Hwan Kim, Shabatun Jamila Islam, Ayman Samman Tahhan, Anurag Mehta, Syed Ahmad, Nour Beydoun, Kiran Ejaz, Devinder Dhindsa, Ayman Alkhoder, Yi-An Ko, Laurence Sperling, Rye David, Arshed Quyyumi
Journal: Journal of the American College of Cardiology (2021)
Rapid Emergence and Epidemiologic Characteristics of the SARS-CoV-2 B.1.526 Variant — New York City, New York, January 1–April 5, 2021
Authors: Corinne N. Thompson, Scott Hughes, Stephanie Ngai, Jennifer Baumgartner, Jade C. Wang, Emily McGibbon, Katelynn Devinney, Elizabeth Luoma, Daniel Bertolino, Christina Hwang, Kelsey Kepler, Cybill Del Castillo, Melissa Hopkins, Henry Lee, Andrea K. DeVito, Jennifer L. Rakeman, Anne D. Fine
Journal: MMWR Morbidity and Mortality Weekly Report (2021)

Recent studies have documented the emergence and rapid growth of B.1.526, a novel variant of interest (VOI) of SARS-CoV-2, the virus that causes COVID-19, in the New York City (NYC) area after its identification in NYC in November 2020.
TEMPORAL TRENDS IN INCIDENCE AND OUTCOMES OF PERIPARTUM CARDIOMYOPATHY IN THE UNITED STATES: A COMPARISON OF FINDINGS FROM THE NATIONAL INPATIENT SAMPLE DATABASE FOR THE YEARS 2012-2016 WITH THE YEARS 2004-2011
Authors: Jian Liang Tan, Vittorio Terrigno, Philip Olsen, Krystal Hunter, Joanne Mazzarelli
Journal: Journal of the American College of Cardiology (2021)
Self-control (or willpower) seeks to bias the resolution of motivational conflicts toward an individual's long-term interests
Authors: Samuel A. Nordli, Edward R. Hirt
Journal: Behavioral and Brain Sciences (2021)

Abstract We define self-control as an individual's efforts to bias the outcome of present or anticipated motivational conflicts in order to increase the likelihood that subsequent behavior serves perceived long-term interests. We suggest suppression and resolve are not “mechanisms” that underlie self-control, but rather are classes of strategies that influence motivations in order to increase the likelihood of successful self-control outcomes.
Results Of The DFCI ALL Consortium Protocol 05-001 For Children and Adolescents With Newly Diagnosed ALL
Authors: Lewis B. Silverman, Kristen E. Stevenson, Uma H. Athale, Luis A. Clavell, Peter Cole, Kara A. Kelly, Jean-Marie Leclerc, Bruno Michon, Marshall A. Schorin, Cindy L Schwartz, Barbara Asselin, Jeffrey G Supko, Sarah Hunt, Place Andrew, Lynda M. Vrooman, Donna S. Neuberg, Stephen E. Sallan
Journal: Blood (2013)
ACUTE STENT THROMBOSIS AFTER ADMINISTRATION OF RECOMBINANT VON WILLEBRAND FACTOR IN A PATIENT WITH VON WILLEBRAND DISEASE TYPE I: A CASE REPORT AND CAUTIONARY TALE
Authors: Yogamaya Mantha, Kevin Tayon, Michinari Hieda, Andrew Assaf, Uday Tatiraju, Kenneth Saland
Journal: Journal of the American College of Cardiology (2021)
Appropriate Systemic Therapy Dosing for Obese Adult Patients With Cancer: ASCO Guideline Update
Authors: Jennifer J. Griggs, Kari Bohlke, Edward P. Balaban, James J. Dignam, Evan T. Hall, R. Donald Harvey, Diane P. Hecht, Kelsey A. Klute, Vicki A. Morrison, T. May Pini, Gary L. Rosner, Carolyn D. Runowicz, Michelle Shayne, Alex Sparreboom, Sophia Turner, Corrine Zarwan, Gary H. Lyman
Journal: Journal of Clinical Oncology (2021)

To provide recommendations for appropriate dosing of systemic antineoplastic agents in obese adults with cancer.A systematic review of the literature collected evidence regarding dosing of chemotherapy, immunotherapy, and targeted therapies in obese adults with cancer. PubMed and the Cochrane Library were searched for randomized controlled trials, meta-analyses, or cohort studies published from November 1, 2010, through March 27, 2020. ASCO convened an Expert Panel to review the evidence and formulate recommendations.Sixty studies, primarily retrospective, were included in the review. Overall, the evidence supported previous findings that obese adult patients tolerate full, body-size-based dosing of chemotherapy as well as nonobese patients. Fewer studies have addressed the dosing of targeted therapies and immunotherapies in relation to safety and efficacy in obese patients.The Panel continues to recommend that full, weight-based cytotoxic chemotherapy doses be used to treat obese adults with cancer. New to this version of the guideline, the Panel also recommends that full, approved doses of immunotherapy and targeted therapies be offered to obese adults with cancer. In the event of toxicity, the consensus of the Panel is that dose modifications of systemic antineoplastic therapies should be handled similarly for obese and nonobese patients. Important areas for future research include the impact of sarcopenia and other measures of body composition on optimal antineoplastic dosing, and more customized dosing based on pharmacokinetic or pharmacogenetic factors.Additional information is available at www.asco.org/supportive-care-guidelines.
A Prospective Diet-Wide Association Study for Risk of Colorectal Cancer in EPIC
Authors: Nikos Papadimitriou, Emmanouil Bouras, Piet A. van den Brandt, David C. Muller, Areti Papadopoulou, Alicia K. Heath, Elena Critselis, Marc J. Gunter, Paolo Vineis, Pietro Ferrari, Elisabete Weiderpass, Heiner Boeing, Nadia Bastide, Melissa A. Merritt, David S. Lopez, Manuela M. Bergmann, Aurora Perez-Cornago, Matthias Schulze, Guri Skeie, Bernard Srour, Anne Kirstine Eriksen, Stina Boden, Ingegerd Johansson, Therese Haugdahl Nøst, Marco Lukic, Fulvio Ricceri, Ulrika Ericson, José María Huerta, Christina C. Dahm, Claudia Agnoli, Pilar Exezarreta Amiano, Anne Tjønneland, Aurelio Barricarte Gurrea, Bas Bueno-de-Mesquita, Eva Ardanaz, Jonna Berntsson, Maria-Jose Sánchez, Rosario Tumino, Salvatore Panico, Verena Katzke, Paula Jakszyn, Giovanna Masala, Jeroen W.G. Derksen, J. Ramón Quirós, Gianluca Severi, Amanda J. Cross, Ellio Riboli, Ioanna Tzoulaki, Konstantinos K. Tsilidis
Journal: Clinical Gastroenterology and Hepatology (2021)
THE SAFETY AND EFFICACY OF PERCUTANEOUS CORONARY INTERVENTION FOR MYOCARDIAL BRIDGING VERSUS MEDICAL MANAGEMENT: INSIGHTS FROM THE NATIONAL INPATIENT SAMPLE
Authors: Hafez MA Abdullah, Waqas Ullah, Sardar Hasan, Salman FNU, Sameer Saleem, Salman Zahid, Mohamed Zghouzi, David Fischman
Journal: Journal of the American College of Cardiology (2021)
CSL112 (APOLIPOPROTEIN A-I [HUMAN]) SIMILARLY ENHANCES CHOLESTEROL EFFLUX CAPACITY IN JAPANESE AND CAUCASIAN SUBJECTS: FINDINGS FROM A PHASE 1 STUDY
Authors: Michael Tortorici, Regina Clementi, John Feaster, Bo Zheng, Danielle Duffy, Penelope Dalitz, Jolanta Airey, John Roberts
Journal: Journal of the American College of Cardiology (2021)
PHOTOPLETHYSMOGRAPHY APPLICATIONS VS. 12-LEAD EKG FOR ATRIAL FIBRILLATION SCREENING - A DIAGNOSTIC ACCURACY META-ANALYSIS
Authors: M. Chadi Alraies, Yasar Sattar, Deepika Sarvepalli, Waqas Ullah, Syeda Ramsha Zaidi, Junaid Arshad, Tanveer Mir, Islam Elgendy, Waqas Qureshi, Mohamed Zghouzi, Abdul-Rahman Suleiman, Zaher Hakim, Mazhar Khan, Nagib Chalfoun
Journal: Journal of the American College of Cardiology (2021)
TROUBLESHOOTING AN IMPELLA- NOVEL SNARING TECHNIQUE FOR DE-KINKING THE IMPELLA CP
Authors: Sundeep Kumar, Ruthvik Srinivasamurthy, Preetham Reddy Muskula, Hiren Patel, Ali Ghani, Ziad SayedAhmad, Khadeeja Ashai, Ammar Nasir, Elsayed Abo-Salem
Journal: Journal of the American College of Cardiology (2021)
OPTIMAL ANTITHROMBOTIC THERAPY FOR ATRIAL FIBRILLATION AND STABLE CORONARY ARTERY DISEASE - A NETWORK META-ANALYSIS
Authors: Rahul Gupta, Aaqib Malik, Ross Biggs, Sagar Vadhar, Lekha Racharla, Makoto Nagahama, Apurva Vyas, Nainesh Patel
Journal: Journal of the American College of Cardiology (2021)
Covid-19: Investigation probes Bolsonaro’s role in Brazil’s failed pandemic response
Authors: Luke Taylor
Journal: BMJ (2021)

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Covid-19: Booster vaccine to be rolled out in autumn as UK secures 60m more Pfizer doses
Authors: Elisabeth Mahase
Journal: BMJ (2021)

Covid-19: Booster vaccine to be rolled out in autumn as UK secures 60m more Pfizer doses Elisabeth MahaseThe UK will roll out a covid-19 booster vaccine at the beginning of autumn in order to protect the most vulnerable ahead of winter, the Department of Health and Social Care (DHSC) has announced.
PROGNOSTIC IMPACT OF TRANS-CATHETER ATRIAL FIBRILLATION ABLATION ON HYPERTROPHIC CARDIOMYOPATHY OUTCOME: A MULTICENTER RETROSPECTIVE LONG-TERM FOLLOW UP STUDY
Authors: Stefano Albani, Andrea Rocotti, Paola Berchialla, Sergio Bongioanni, Barbara Mabritto, Stefania Luceri, Iris Parrini, Antonino Tommasello, Alfredo Pizzuti, Francesca Bianchi, Antonia Buongiorno, Antonio De Luca, Giulia Grilli, Bruno Pinamonti, Marco Merlo, Massimo Zecchin, Stefano Grossi, Gianfranco Sinagra, Giuseppe Musumeci
Journal: Journal of the American College of Cardiology (2021)
Stimulation of lung adenocarcinoma by beta-carotene
Authors: Hussein A. Al-Wadei, Takashi Takahashi, Hildegard M. Schuller
Journal: Cancer Research (2005)

6081  Numerous laboratory studies have shown that the pro-vitamin beta-carotene inhibits the development of cancer from upper airway epithelia. However, in clinical trials it increased mortality from lung cancer and cardiovascular disease. Our studies in human pulmonary adenocarcinoma cells (PAC) and their putative cells of origin, small airway epithelial cells (SAEC), show that beta-carotene (1 pM to 200 nM) stimulated the growth of both cell systems as monitored by MTT assays. By contrast, beta-carotene inhibited the growth of human large airway epithelial cells. Using immunoassays, PKA activation assays and Western blots, we provide evidence suggesting that the proliferative response of SAEC and PAC to beta-carotene was mediated via an increase in intracellular cAMP and activation of PKA, CREB and ERK1/2.These findings suggest that beta-carotene may selectively promote the development of PAC and should not be used as chemopreventive agent. The growth stimulating effects of beta-carotene on SAEC and PAC may have caused the unfortunate outcome of clinical trials with this agent. Moreover, our findings are the first report that links the activation of PKA/CREB with the growth regulation of a specific type of lung cancer. Our findings are in accord with our recent discovery that beta-adrenergic agonists and the cAMP activator forskolin promote the growth of PAC in vitro and in a hamster model in vivo.
INITIAL CLINICAL AND HEMODYNAMIC RESULTS OF A US REGIONAL BALLOON PULMONARY ANGIOPLASTY PROGRAM
Authors: Ali J. Noory, Arslan Mirza, Estefania Oliveros Soles, Vladimir Lakhter, Meredith Brisco-Bacik, William Auger, Anjali Vaidya, Paul Forfia, Riyaz Bashir
Journal: Journal of the American College of Cardiology (2021)
TAKOTSUBO CARDIOMYOPATHY (TCM) AND REFRACTORY SHOCK EXACERBATED BY LEFT VENTRICULAR OUTFLOW TRACT OBSTRUCTION (LVOTO)
Authors: Rakhee R Makhija, Clifton Espinoza, Adriana Mares, Kazue Okajima, Chandra Ojha, Ahmed Ibrahim
Journal: Journal of the American College of Cardiology (2021)
Katherine Brenda Mansfield
Authors: Nick Mansfield
Journal: BMJ (2021)

Katherine Brenda Kelly (“Katie”) was born in Lerwick. Her mother was a Shetlander and her father a Bristolian, but they met in India during the second world war as an army nurse and Royal Air Force fighter pilot, respectively. Although the family moved away from Shetland when she was 2, that heritage remained important to her, and she and her family visited the islands regularly. Her parents worked overseas in Nigeria, Saudi Arabia, and Somalia, so Katie attended boarding school at Poles Convent in Ware. She then stayed with a friend while a sixth former at John F Kennedy School in Hemel Hempstead and was their first student …
VALIDATION OF THE CARDIAC ARREST SURVIVAL SCORE IN AN URBAN POPULATION OF OUT-OF-HOSPITAL CARDIAC ARRESTS
Authors: Arjun Aggarwal, Manoj Thangam, Nisha Soneji, Nabeel Saghir, Mark Escott, Prakash Balan, Pratik Doshi, Peter Monteleone, Clay Cauthen, George Rodgers
Journal: Journal of the American College of Cardiology (2021)
LONG-TERM CLINICAL IMPACT OF CONTRAST-ASSOCIATED ACUTE KIDNEY INJURY FOLLOWING PCI AN ADAPT-DES SUB-STUDY
Authors: Reza Mohebi, Keyvan Karimi Galougahi, Javier Jas Garcia, Jennifer Horst, Jai Radhakrishnan, Shawnbir Gogia, Sumit Mohan, Glen Chertow, Steven Rucker, Akiko Maehara, Allen Jeremias, David Cohen, Gary Mintz, Shmuel Chen, Bjorn Redfors, Ori Ben-Yehuda, Martin Leon, Thomas Stuckey, Michael Rinaldi, Giora Weisz, Bernhard Witzenbichler, Ajay Kirtane, Roxana Mehran, Gregg Stone, Ziad Ali
Journal: Journal of the American College of Cardiology (2021)
FIVE-YEAR OUTCOMES COMPARING SURGICAL VERSUS TRANSCATHETER AORTIC VALVE REPLACEMENT IN INTERMEDIATE-RISK PATIENTS WITH CHRONIC KIDNEY DISEASE
Authors: Santiago Garcia, Roberto Cubeddu, Craig Asher, Philippe Pibarot, Rebecca Hahn, Samir Kapadia, Susheel Kodali, Vinod Thourani, Julien Ternacle, Wael Jaber, Sammy Elmariah, Raj Makkar, John Webb, Howard Herrmann, Michael Lu, Chandan Devireddy, S. Chris Malaisrie, Craig Smith, Michael Mack, Martin Leon
Journal: Journal of the American College of Cardiology (2021)
DETERMINANTS OF TRANSPORTATION BARRIERS AMONG ADULTS WITH ATHEROSCLEROTIC CARDIOVASCULAR DISEASE
Authors: Isaac Acquah, Javier Valero-Elizondo, Zulqarnain Javed, Kobina Hagan, Tamer Yahya, Safi Khan, Miguel Cainzos-Achirica, Khurram Nasir
Journal: Journal of the American College of Cardiology (2021)
Corrigendum to “Viscosity and degradation controlled injectable hydrogel for esophagealendoscopic submucosal dissection” [Bioact. Mater. 6 (2021) 1150-1162]
Authors: Chaoqiang Fan, Kaige Xu, Yu Huang, Shuang Liu, Tongchuan Wang, Wei Wang, Weichao Hu, Lu Liu, Malcolm Xing, Shiming Yang
Journal: Bioactive Materials (2021)
PERFORMANCE OF CURRENT THROMBOEMBOLISM RISK ASSESSMENT TOOLS IN PATIENTS WITH SEVERE COVID-19
Authors: Luis H. Paz Rios, Iva Minga, Esther Kwak, Ayman Najib, Ashley Aller, Elizabeth Lees, Victor Macrinici, Kaveh Rezaei Bookani, Amit Pursnani, Alfonso Tafur
Journal: Journal of the American College of Cardiology (2021)
EFFECT OF ELIMINATING PRE-DISCHARGE TRANSTHORACIC ECHOCARDIOGRAM ON OUTCOMES AFTER TAVR
Authors: Garrett A. Welle, Bassim El-Sabawi, Jeremy Thaden, Kevin Greason, Kyle Klarich, Vuyisile Nkomo, Mohamad Alkhouli, Mayra Guerrero, Juan Crestanello, Rajiv Gulati, Charanjit Rihal, Mackram Eleid
Journal: Journal of the American College of Cardiology (2021)
THE RELATIONSHIP BETWEEN BIOMARKERS OF INFLAMMATION AND LEFT VENTRICULAR STRUCTURE AND FUNCTION
Authors: Adebamike Oshunbade, Tran T. Le, Seth Lirette, Arsalan Hamid, Lena Mathews, Daisuke Kamimura, Robert Mentz, Ervin Fox, Michael McMullan, Javed Butler, Kenneth Butler, Thomas Mosley, Michael Hall
Journal: Journal of the American College of Cardiology (2021)
CLINICAL IMPACT OF CORONARY PERFORATIONS DURING CHRONIC TOTAL OCCLUSION RECANALIZATION: A 2.566 PATIENT POOLED ANALYSIS FROM A LATIN AMERICAN (LATAM) REGISTRY
Authors: Marcelo Harada Ribeiro, Alexandre Quadros, Alfredo Galassi, Gustavo Araujo, Lucio Padilla, Pedro Oliveira, Franklin Hanna, Ricardo Santiago, Antonio Botelho, Luis Dallan, Lorenzo Azzalini, Marouane Boukhris, Luciano Santos, Karlyse Belli, Vinicius Seleme, Maria Antonieta Albanez, Marco Alcantra, Alexandre Abizaid, Carlos Campos
Journal: Journal of the American College of Cardiology (2021)
Bispecific Antibodies to PD-1 and CTLA4: Doubling Down on T Cells to Decouple Efficacy from Toxicity
Authors: Elizabeth M. Burton, Hussein A. Tawbi
Journal: Cancer Discovery (2021)

Abstract Summary: Although combination anti–PD-1 and anti-CTLA4 mAbs have revolutionized outcomes for many cancers, their utility has been limited due to significant immune-related toxicities and the emergence of resistance. In this issue of Cancer Discovery, Dovedi and colleagues describe the development and preclinical testing of MEDI5752, a bispecific anti–PD-1/CTLA4 antibody designed to optimize therapeutic response by maximizing CTLA4 blockade on antigen-experienced T cells, thereby increasing efficacy and potentially minimizing toxicity. See related article by Dovedi et al., p. 1100.
Anna Rachel Lewis
Authors: Kath Shakespeare, Kate Lewis, Ruth Willot
Journal: BMJ (2021)

Anna Rachel Lewis was born in Leicester on 24 January 1980 to Len and Kath. She was educated at Longslade Community College and trained at the University of Sheffield, graduating in the top 10% of her year. She worked at Sheffield Teaching Hospitals, where she completed her core medical training before embarking on the global odyssey in 2010 with her beloved sister, Kate, that was to bring her so much joy, and so many new friends.

By 2012 Anna was working as a medical registrar at Tauranga Hospital, New Zealand. When her consultant there became terminally ill, Anna and some of her colleagues took it on themselves to care for him around the clock so that …
EXPLORING THE RELATIONSHIP BETWEEN PERIVASCULAR CORONARY INFLAMMATION AND DOWNSTREAM MICROCIRCULATORY FUNCTION IN NON-OBSTRUCTIVE CORONARY ARTERY DISEASE
Authors: Harsh V. Thakkar, Jasmine Chan, Andrea Comella, Udit Thakur, Abdul Rahman Ihdayhid, Nitesh Nerlekar, Adam J. Brown, Monash Heart
Journal: Journal of the American College of Cardiology (2021)
The complex nature of willpower and conceptual mapping of its normative significance in research on stress, addiction, and dementia
Authors: Veljko Dubljević, Shevaun D. Neupert
Journal: Behavioral and Brain Sciences (2021)

Abstract Willpower (as suppression, resolve, and habit) has ramifications for autonomy and mental time-travel. Autonomy presupposes mature powers of volition and the capacity to anticipate future events and consequences of one's actions. Ainslie's study is useful to clarify basic autonomy in addiction and dementia. Furthermore, we show how our study on coping with stress can be applied to suppression and resolve.
CONTEMPORARY PRACTICE IN SURGICAL MANAGEMENT OF CONGENITALLY CORRECTED TRANSPOSITION OF THE GREAT ARTERIES:AN ANALYSIS THE SOCIETYOF THORACIC SURGEONS CONGENITAL HEART SURGERY DATABASE(STS-CHD)
Authors: Joshua Chew, Kevin Hill, Jonathan Soslow, Marshall Jacobs, Jeffrey Jacobs, Pirooz Eghtesady, Dylan Thibault, Karen Chiswell, David Bichell, Justin Godown
Journal: Journal of the American College of Cardiology (2021)
Bimagrumab to improve recovery after hip fracture in older adults: a multicentre, double-blind, randomised, parallel-group, placebo-controlled, phase 2a/b trial
Authors: Lorenz C Hofbauer, Richard Witvrouw, Zsuzsanna Varga, Naofumi Shiota, Malika Cremer, Laszlo B Tanko, Daniel Rooks, Lixin Zhang Auberson, Michal Arkuszewski, Nathalie Fretault, Agnes Annette Schubert-Tennigkeit, Dimitris A Papanicolaou, Chris Recknor
Journal: The Lancet Healthy Longevity (2021)
Stewart-Treves Syndrome
Authors: Eduardo Bernia, Elisa Rios-Viñuela, Celia Requena
Journal: JAMA Dermatology (2021)

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DEEP PHENOTYPING USING UNSUPERVISED MACHINE LEARNING OF HFPEF PATIENTS WITH DIABETES MELLITUS IN THE TOPCAT AMERICAS COHORT
Authors: Ian Atkinson, Kabir Al-Tariq, Gauri Dandi, Nuha Gani, Zyannah Mallick, Victoria Xin, Areeb Gani, Noah Hasan, Scout Hayashi, Nayab Mahmood, Khizar Qureshi, Natalie Lewis, Avantika Banerjee, Amit Dey, Anwar Husain, Yves Rosenberg, Ahmed Hasan
Journal: Journal of the American College of Cardiology (2021)
BUSTED: MANAGEMENT OF PULMONARY EMBOLISM INAPATIENT WITH FONTAN PHYSIOLOGY
Authors: Peter Evans, Taisei Kobayashi, Yoav Dori, Sara Partington, Yuli Kim, Jay Giri, Srinath Adusumalli, Matthew Seigerman, Ashwin Murthy, Howard Julien
Journal: Journal of the American College of Cardiology (2021)