tbuckley/cabot-search huggingface dataset:
Abstract 14957: Measurements of in vivo Platelet Activation and Aggregation Following Administration of Ticagrelor at the Time of Acute Type 1 Myocardial Infarction in Diabetics and Non-Diabetics
Authors: Narayana Sarma V Singam, Bahjat AlAdili, Alok R Amraotkar, Amanda Coulter, Siddhesh Kulkarni, Mitra Riten, Andrew P Defilippis, Omar N Daham
Journal: Circulation (2019)

Background: Patients with diabetes mellitus have more thrombotic complications and higher mortality than those without diabetes when presenting with a type-1 myocardial infarction (MI). CD40 ligand...
Transcriptomic investigation reveals donor-specific gene signatures in human lung transplants
Authors: Cristina Baciu, Andrew Sage, Ricardo Zamel, Jason Shin, Xiao-Hui Bai, Olivia Hough, Mamatha Bhat, Jonathan C. Yeung, Marcelo Cypel, Shaf Keshavjee, Mingyao Liu
Journal: European Respiratory Journal (2020)

Introduction Transplantation of lungs from donation after circulatory death (DCD) in addition to donation after brain death (DBD) became routine worldwide to address the global organ shortage. The development of ex vivo lung perfusion (EVLP) for donor lung assessment and repair contributed to the increased use of DCD lungs. We hypothesise that a better understanding of the differences between lungs from DBD and DCD donors, and between EVLP and directly transplanted (non-EVLP) lungs, will lead to the discovery of the injury-specific targets for donor lung repair and reconditioning. Methods Tissue biopsies from human DBD (n=177) and DCD (n=65) donor lungs, assessed with or without EVLP, were collected at the end of cold ischaemic time. All samples were processed with microarray assays. Gene expression, network and pathway analyses were performed using R, Ingenuity Pathway Analysis and STRING. Results were validated with protein assays, multiple logistic regression and 10-fold cross-validation. Results Our analyses showed that lungs from DBD donors have upregulation of inflammatory cytokines and pathways. In contrast, DCD lungs display a transcriptome signature of pathways associated with cell death, apoptosis and necrosis. Network centrality revealed specific drug targets to rehabilitate DBD lungs. Moreover, in DBD lungs, tumour necrosis factor receptor-1/2 signalling pathways and macrophage migration inhibitory factor-associated pathways were activated in the EVLP group . A panel of genes that differentiate the EVLP from the non-EVLP group in DBD lungs was identified. Conclusion The examination of gene expression profiling indicates that DBD and DCD lungs have distinguishable biological transcriptome signatures.
Igh Translocation with Undefined Partners Is Associated with Superior Outcome in Multiple Myeloma Patients
Authors: Xue-Han Mao, Yan Xu, Yuting Yan, Junling Zhuang, Huishou Fan, Weiwei Sui, Jiahui Liu, Shuhui Deng, Shuhua Yi, Lugui Qiu, Gang An
Journal: Blood (2020)
Racial Variations in Mutational Profile in Newly Diagnosed Acute Myeloid Leukemia Patients
Authors: Tahsin Anwar, Mohammed Mian, Mahran Shoukier, Achuta K Guddati, Moinul Hossain, Ravindra Kolhe, Locke J. Bryan, Anand P Jillella, Jorge E. Cortes, Vamsi Kota
Journal: Blood (2020)
A Protease-Mediated Regulatory Chimeric Antigen Receptor (CAR): "Double Arm" CAR System Improves Tumor-Cell-Specificity of CAR-T Cell Therapy
Authors: Satoru Aoyama, Shunichiro Yasuda, Daisuke Watanabe, Hiroki Akiyama, Yoshihiro Umezawa, Ayako Nogami, Osamu Miura, Norihiko Kawamata
Journal: Blood (2020)
Efficacy of Daratumumab (Dara)-Based Regimens for the Treatment of Plasma Cell Leukemia (PCL)
Authors: Ricardo Parrondo, Muhamad Alhaj Moustafa, Craig B. Reeder, Taimur Sher, Vivek Roy, Rahma M Warsame, Victoria R. Alegria, Wilson I Gonsalves, Prashant Kapoor, David Dingli, Suzanne R. Hayman, Asher A. Chanan-Khan, Sikander Ailawadhi
Journal: Blood (2020)
Abstract 12257: Interplay Between Temporal and Spatial Dispersion of Repolarization in the Initiation and Perpetuation of Torsade De Pointes Arrhythmias
Authors: Agnieszka Smoczynska, Errol W Aarnink, Albert Dunnink, Alexandre Bossu, Valerie Y Weperen, Veronique Meijborg, Henriëtte D Beekman, Marc A Vos
Journal: Circulation (2019)

Introduction: Ventricular arrhythmias, consisting of single ectopic beats (sEB), multiple EB (mEB), and Torsade de Pointes (TdP, defined as >5 beats with QRS vector twisting around isoelectric line...
Whole-Genome Sequencing Reveals Evidence of Two Biologically and Clinically Distinct Entities: Progressive <i>Versus</i> Stable Myeloma Precursor Disease
Authors: Bénedith Oben, Guy Froyen, Kylee H Maclachlan, Binbin Zheng-Lin, Venkata Yellapantula, Federico Abascal, Daniel A. Leongamornlert, Andriy Derkach, Ellen Geerdens, Benjamin Diamond, Ingrid Arijs, Brigitte Maes, Kimberly Vanhees, Malin Hultcrantz, Ahmet Dogan, Yanming Zhang, Aneta Mikulasova, Brian Walker, Gareth Morgan, Peter J Campbell, Ola Landgren, Jean-Luc Rummens, Niccolo Bolli, Francesco Maura
Journal: Blood (2020)
YTHDF2 mediates the mRNA degradation of the tumor suppressors to induce AKT phosphorylation in N6-methyladenosine-dependent way in prostate cancer
Authors: Jiangfeng Li, Haiyun Xie, Yufan Ying, Hong Chen, Huaqing Yan, Liujia He, Mingjie Xu, Xin Xu, Zhen Liang, Ben Liu, Xiao Wang, Xiangyi Zheng, Liping Xie
Journal: Molecular Cancer (2020)

N6-methyladenosine (m6A) is the most abundant modification in mRNA of humans. Emerging evidence has supported the fact that m6A is comprehensively involved in various diseases especially cancers. As a crucial reader, YTHDF2 usually mediates the degradation of m6A-modified mRNAs in m6A-dependent way. However, the function and mechanisms of m6A especially YTHDF2 in prostate cancer (PCa) still remain elusive.To investigate the functions and mechanisms of YTHDF2 in PCa, in vitro, in vivo biofunctional assays and epigenetics experiments were performed. Endogenous expression silencing of YTHDF2 and METTL3 was established with lentivirus-based shRNA technique. Colony formation, flow cytometry and trans-well assays were performed for cell function identifications. Subcutaneous xenografts and metastatic mice models were combined with in vivo imaging system to investigate the phenotypes when knocking down YTHDF2 and METTL3. m6A RNA immunoprecipitation (MeRIP) sequencing, mRNA sequencing, RIP-RT-qPCR and bioinformatics analysis were mainly used to screen and validate the direct common targets of YTHDF2 and METTL3. In addition, TCGA database was also used to analyze the expression pattern of YTHDF2, METTL3 and the common target LHPP in PCa, and their correlation with clinical prognosis.The upregulated YTHDF2 and METTL3 in PCa predicted a worse overall survival rate. Knocking down YTHDF2 or METTL3 markedly inhibited the proliferation and migration of PCa in vivo and in vitro. LHPP and NKX3-1 were identified as the direct targets of both YTHDF2 and METTL3. YTHDF2 directly bound to the m6A modification sites of LHPP and NKX3-1 to mediate the mRNA degradation. Knock-down of YTHDF2 or METTL3 significantly induced the expression of LHPP and NKX3-1 at both mRNA and protein level with inhibited phosphorylated AKT. Overexpression of LHPP and NKX3-1 presented the consistent phenotypes and AKT phosphorylation inhibition with knock-down of YTHDF2 or METTL3. Phosphorylated AKT was consequently confirmed as the downstream of METTL3/YTHDF2/LHPP/NKX3-1 to induce tumor proliferation and migration.We propose a novel regulatory mechanism in which YTHDF2 mediates the mRNA degradation of the tumor suppressors LHPP and NKX3-1 in m6A-dependent way to regulate AKT phosphorylation-induced tumor progression in prostate cancer. We hope our findings may provide new concepts of PCa biology.
Evaluation of Multiple Myeloma Clinical Decision Support Tool Value When Populated with Community Health System Data
Authors: Steven E. Labkoff, Kathy E. Giusti, Paul A. Giusti, Ryan Wilcox, Derrick Haslem, Daanish Hoda, Kerry Rowe, Gail Fulde, Jesse Gygi, Brad Bott, Ben Smith
Journal: Blood (2020)
TM-028. ELECTRIC FIELDS FOR THE TREATMENT OF GLIOBLASTOMAS: A MODELING STUDY
Authors: Cornelia Wenger, Pedro Miranda, Abeye Mekonnen, Ricardo Salvador, Peter Basser
Journal: Neuro-Oncology (2013)

Oscillating electric fields are being investigated as an adjunct and even an alternative to chemotherapy in the treatment of glioblastoma multiforme. According to in vitro studies, an electric field strength greater than 1 V/cm is necessary to achieve inhibition of tumor growth. Here we used a reali
Evaluation of Concordance Between Original Death Certifications and an Expert Panel Process in the Determination of Sudden Unexplained Death in Childhood
Authors: Laura Gould Crandall, Joyce H. Lee, Daniel Friedman, Kelly Lear, Katherine Maloney, J. Keith Pinckard, Peter Lin, Thomas Andrew, Kristin Roman, Kristen Landi, Heather Jarrell, Alex K. Williamson, J. C. Upshaw Downs, Kathy Pinneri, Christopher William, Joseph J. Maleszewski, R. Ross Reichard, Orrin Devinsky
Journal: JAMA Network Open (2020)

<h3>Importance</h3> The true incidence of sudden unexplained death in childhood (SUDC), already the fifth leading category of death among toddlers by current US Centers for Disease Control and Prevention estimates, is potentially veiled by the varied certification processes by medicolegal investigative offices across the United States. <h3>Objective</h3> To evaluate the frequency of SUDC incidence, understand its epidemiology, and assess the consistency of death certification among medical examiner and coroner offices in the US death investigation system. <h3>Design, Setting, and Participants</h3> In this case series, 2 of 13 forensic pathologists (FPs) conducted masked reviews of 100 cases enrolled in the SUDC Registry and Research Collaborative (SUDCRRC). Children who died aged 11 months to 18 years from 36 US states, Canada, and the United Kingdom had been posthumously enrolled in the SUDCRRC by family members from 2014 to 2017. Comprehensive data from medicolegal investigative offices, clinical offices, and family members were reviewed. Data analysis was conducted from December 2014 to June 2020. <h3>Main Outcomes and Measures</h3> Certified cause of death (COD) characterized as explained (accidental or natural) or unexplained, as determined by SUDCRRC masked review process. <h3>Results</h3> In this study of 100 cases of SUDC (mean [SD] age, 32.1 [31.8] months; 58 [58.0%] boys; 82 [82.0%] White children; 92 [92.0%] from the United States), the original pathologist certified 43 cases (43.0%) as explained COD and 57 (57.0%) as unexplained COD. The SUDCRRC review process led to the following certifications: 16 (16.0%) were explained, 7 (7.0%) were undetermined because of insufficient data, and 77 (77.0%) were unexplained. Experts disagreed with the original COD in 40 cases (40.0%). These data suggest that SUDC incidence is higher than the current Centers for Disease Control and Prevention estimate (ie, 392 deaths in 2018). <h3>Conclusions and Relevance</h3> To our knowledge, this is the first comprehensive masked forensic pathology review process of sudden unexpected pediatric deaths, and it suggests that SUDC may often go unrecognized in US death investigations. Some unexpected pediatric deaths may be erroneously attributed to a natural or accidental COD, negatively affecting surveillance, research, public health funding, and medical care of surviving family members. To further address the challenges of accurate and consistent death certification in SUDC, future studies are warranted.
circCUL2 regulates gastric cancer malignant transformation and cisplatin resistance by modulating autophagy activation via miR-142-3p/ROCK2
Authors: Lei Peng, Huaiming Sang, Shuchun Wei, Yuanyuan Li, Duochen Jin, Xudong Zhu, Xuan Li, Yini Dang, Guoxin Zhang
Journal: Molecular Cancer (2020)

Abstract Background Circular RNAs (circRNAs) are a class of noncoding RNAs (ncRNAs) and can modulate gene expression by binding to miRNAs; further, circRNAs have been shown to participate in several pathological processes. However, the expression and biological function of circCUL2 in gastric cancer (GC) remains largely unknown. Methods circRNA microarrays and quantitative real-time PCR (qRT-PCR) were used to identify differentially expressed circRNAs in GC tissues and cell lines. circCUL2 knockdown and overexpression were performed to indicate the functional role of circCUL2 in vitro and in vivo. The expression and regulation of circCUL2, miR-142-3p and ROCK2 were evaluated using fluorescence in situ hybridization (FISH), dual-luciferase assays, RNA pull-down assays, RNA immunoprecipitation (RIP) and rescue experiments. Furthermore, the regulation of cisplatin sensitivity and autophagy by circCUL2/miR-142-3p/ROCK2 was demonstrated by cellular apoptosis assays, western blot, immunofluorescence and transmission electron microscopy analyses. Results The level of circCUL2, which is stable and cytoplasmically localized, was significantly reduced in GC tissues and cells. Overexpressed circCUL2 inhibited malignant transformation in vitro and tumorigenicity in vivo. In the AGS and SGC-7901 cell lines, circCUL2 sponged miR-142-3p to regulate ROCK2, thus modulating tumor progression. Furthermore, in the AGS/DDP and SGC-7901/DDP cell lines, circCUL2 regulated cisplatin sensitivity through miR-142-3p/ROCK2-mediated autophagy activation. Conclusion circCUL2 may function as a tumor suppressor and regulator of cisplatin sensitivity through miR-142-3p/ROCK2-mediated autophagy activation, which could be a key mechanism and therapeutic target for GC.
Mix for Regeneration: Nephron Replacement by Transplanted Cells
Authors: Kai M. Schmidt-Ott
Journal: Journal of the American Society of Nephrology (2020)

CKD poses a substantial burden on society. Dialysis and allogenic kidney transplantation provide imperfect solutions. CKD, independent of its underlying etiology, is characterized by a progressive loss of the kidneys’ nephrons, by a rarefaction of its vasculature, and by an expansion of its
Abstract 13205: Incremental Diagnostic Yield of 4 Weeks versus 2 Weeks of Ambulatory Heart Rhythm Monitoring for the Detection of Non-Sustained Ventricular Tachycardia: The Atherosclerosis Risk in Communities (ARIC) Study
Authors: Mary R Rooney, Alvaro Alonso, Faye L Norby, Michael Zhang, Alejandra G Burnal, Jeremy Berman, Pamela L Lutsey, Thomas H Mosley, Josef Coresh, Elsayed Z Soliman, Lin Y Chen
Journal: Circulation (2018)

Introduction: Non-sustained ventricular tachycardia (NSVT) can be asymptomatic and intermittent; thus, its prevalence may be underestimated. Little is known about the diagnostic yield of extending ...
The Prosid Study: Evaluating Efficacy and Safety of Intravenous Immunoglobulin (IVIG) 10% in Primary Infection Prophylaxis in Patients with Chronic Lymphocytic Leukemia- Study Design
Authors: Oliver Cornely, Anthony Mato, Tadeusz Robak, Sibylle Mellinghoff, Tatiana Lavrova
Journal: Blood (2020)
Local and Systemic Effects of Immune Checkpoint Blockade on Relapsed Myeloid Malignancies Following Allogeneic Hematopoietic Stem Cell Transplantation
Authors: Livius Penter, Yi Zhang, Alexandra Savell, Srinika Ranasinghe, Teddy Huang, Nicoletta Cieri, Satyen H Gohil, Wandi Zhang, Shuqiang Li, Robert Zeiser, Haesook T. Kim, Kenneth J. Livak, Jerome Ritz, Donna S. Neuberg, Robert J. Soiffer, X. Shirley Liu, Matthew S. Davids, Pavan Bachireddy, Catherine J. Wu
Journal: Blood (2020)
Photodynamic Therapy in Refractory Mycosis Fungoides: A Prospective, Open-Label Study
Authors: Caitlin M Brumfiel, Kevin J Severson, Meera H Patel, Helen J L Cumsky, Brenda F Ginos, Heidi E. Kosiorek, Monica C Janeczek, Jake Besch-Stokes, William Rule, David DiCaudo, Allison C. Rosenthal, Mark R Pittelkow, Aaron R Mangold
Journal: Blood (2020)
Role of Hypomethylating Agents in Accelerated and Blast Phase of Philadelphia Negative Myeloproliferative Neoplasms: A Systematic Review
Authors: Karun Neupane, Muhammad Salman Faisal, Yazan Samhouri, Israr Khan, Asim Tameez Ud Din, Zahoor Ahmed, Muhammad Aadil Rahman, Ali Younas Khan, Hamid Ehsan, Vinayak Aryal, Syed Maaz Abdullah, Abdul Rafae, Faiz Anwer, Salman Fazal
Journal: Blood (2020)
A Phase 2 Trial of Ibrutinib and Nivolumab in Patients with Relapsed or Refractory Classical Hodgkin's Lymphoma
Authors: Walter Hanel, Beth A. Christian, Kami J. Maddocks, Narendranath Epperla, Basem M. William, Samantha Jaglowski, David A. Bond, Yazeed Sawalha, John C. Reneau, Jonathan E Brammer, Robert Baiocchi, Kristie A. Blum, Lapo Alinari
Journal: Blood (2020)
Characteristics of Rare Coagulation Factors Deficiency in Adults, an Experience from Qatar
Authors: Shehab Fareed Mohamed, Ahmed Abdalhadi, Khalid Elhag, Amna Gamil, Abdulqadir Jeprel Nashwan, Aliaa Amer, Dina Sameh Soliman, Samah Kohla, Mohammed A Yasin
Journal: Blood (2020)
Therapeutic Cancer Vaccination Targeting Shared Tumor Associated Antigens in Combination with Azacitidine for High Risk Myelodysplastic Syndrome - a Phase I Clinical Trial
Authors: Staffan Holmberg-Thydén, Inge Høgh Dufva, Anne Ortved Gang, Marie Fredslund Breinholt, Lone Schejbel, Mette Klarskov Andersen, Mohammad Kadivar, Inge Marie Svane, Kirsten Grønbæk, Sine Reker Hadrup, Daniel El Fassi
Journal: Blood (2020)
Surface Co-presentation of BMP-2 and integrin selective ligands at the nanoscale favors α5β1 integrin-mediated adhesion
Authors: Francesca Posa, Elisabeth H. Baha-Schwab, Qiang Wei, Adriana Di Benedetto, Stefanie Neubauer, Florian Reichart, Horst Kessler, Joachim P. Spatz, Corinne Albiges-Rizo, Giorgio Mori, Elisabetta Ada Cavalcanti-Adam
Journal: Biomaterials (2020)

Here we present the use of surface nanopatterning of covalently immobilized BMP-2 and integrin selective ligands to determine the specificity of their interactions in regulating cell adhesion and focal adhesion assembly. Gold nanoparticle arrays carrying single BMP-2 dimers are prepared by block-copolymer micellar nanolithography and azide-functionalized integrin ligands (cyclic-RGD peptides or α5β1 integrin peptidomimetics) are immobilized on the surrounding polyethylene glycol alkyne by click chemistry. Compared to BMP-2 added to the media, surface immobilized BMP-2 (iBMP-2) favors the spatial segregation of adhesion clusters and enhances focal adhesion (FA) size in cells adhering to α5β1 integrin selective ligands. Moreover, iBMP-2 copresented with α5β1 integrin ligands induces the recruitment of αvβ3 integrins in FAs. When copresented with RGD, iBMP-2 induces the assembly of a higher number of FAs, which are not affected by α5β1 integrin blocking. Our dual-functionalized platforms offer the possibility to study the crosstalk between integrins and BMP receptors, and more in general they could be used to address the spatial regulation of growth factors and adhesion receptors crosstalk on biomimetic surfaces.
A Phase 2 Trial of Daratumumab and Pembrolizumab in Refractory Multiple Myeloma
Authors: Barry Paul, James Symanowski, Paul Osipoff, Sarah Norek, Ami P Ndiaye, Jordan Robinson, Shebli Atrash, Manisha Bhutani, Peter M. Voorhees, Saad Z. Usmani
Journal: Blood (2020)
Worldwide Examination of Patients with CLL Hospitalized for COVID-19
Authors: Lindsey E Roeker, Lydia Scarfo, Thomas Chatzikonstantinou, Pau Abrisqueta, Toby A. Eyre, Raul Cordoba, Ana Muntañola Prat, Guillermo Villacampa, Lori A. Leslie, Michael Koropsak, Giulia Quaresmini, John N. Allan, Richard R. Furman, Erica B Bhavsar, John M. Pagel, Jose Angel Hernandez-Rivas, Krish Patel, Marina Motta, Neil Bailey, Fatima Miras, Nicole Lamanna, Rosalia Alonso, Santiago Osorio-Prendes, Candida Vitale, Manali Kamdar, Patricia Baltasar, Anders Österborg, Lotta Hanson, Mónica Baile, Ines Rodríguez-Hernández, Susana Valenciano, Viola Maria Popov, Abelardo Barez Garcia, Ana Alfayate, Ana C Oliveira, Barbara Eichhorst, Francesca M. Quaglia, Gianluigi Reda, Javier Lopez Jimenez, Marzia Varettoni, Monia Marchetti, Pilar Romero, Rosalía Riaza Grau, Talha Munir, Amaya Zabalza, Ann Janssens, Carsten U Niemann, Guilherme Fleury Perini, Julio Delgado, Lucrecia Yanez San Segundo, Ma Isabel Gómez Roncero, Matthew Wilson, Piers Patten, Roberto Marasca, Sunil Iyengar, Amanda Seddon, Ana Torres, Angela Ferrari, Carolina Cuéllar-García, Daniel Wojenski, Dima El-Sharkawi, Gilad Itchaki, Helen Parry, Juan José Mateos-Mazón, Nicolas Martinez-Calle, Shuo Ma, Daniel Naya, Ellen Van Der Spek, Erlene K. Seymour, Eva Gimeno Vázquez, Gian Matteo Rigolin, Francesca Romana Mauro, Harriet S Walter, Jorge Labrador, Lorenzo De Paoli, Luca Laurenti, Elena Ruiz, Mark-David Levin, Martin Šimkovič, Martin Špaček, Rafa Andreu, Renata Walewska, Sonia Perez-Gonzalez, Suchitra Sundaram, Adrian Wiestner, Amalia Cuesta, Angus Broom, Arnon P. Kater, Begoña Muiña, César A Velasquez, Chaitra S. Ujjani, Cristina Seri, Darko Antic, Dominique Bron, Elisabeth Vandenberghe, Elise A. Chong, Enrico Lista, Fiz Campoy García, Giovanni Del Poeta, Inhye Ahn, Jeffrey J. Pu, Jennifer R Brown, Juan Alfonso Soler Campos, Lara Malerba, Livio Trentin, Lorella Orsucci, Lucia Farina, Lucia Villalon, Maria Jesus Vidal, Maria Jose Sanchez, Maria Jose Terol, Maria Rosaria De Paolis, Massimo Gentile, Matthew S. Davids, Mazyar Shadman, Mohamed A Yassin, Myriam Foglietta, Ozren Jaksic, Paolo Sportoletti, Paul M. Barr, Rafael Ramos, Raquel Santiago, Rosa Ruchlemer, Sabina Kersting, Scott F. Huntington, Tobias Herold, Yair Herishanu, Meghan C. Thompson, Sonia Lebowitz, Christine Ryan, Ryan W. Jacobs, Craig A. Portell, Krista Isaac, Alessandro Rambaldi, Chadi Nabhan, Danielle M. Brander, Emili Montserrat, Giuseppe Rossi, Jose A. Garcia-Marco, Marta Coscia, Nikita Malakhov, Noemi Fernandez-Escalada, Sigrid Strand Skånland, Callie C. Coombs, Paola Ghione, Stephen J. Schuster, Robin Foà, Antonio Cuneo, Francesc Bosch, Kostas Stamatopoulos, Paolo Ghia, Anthony R. Mato, Meera Patel
Journal: Blood (2020)
<i>In Vitro</i> Drug Response Profiling in BCP- and T-ALL Primary Samples Adds a Robust Functional Layer Enabling Optimized Guidance of Individualized Therapy in Relapsed and Refractory Pediatric Acute Leukemia Patients
Authors: Andrej Lissat, Despina Maniotis, Michael Nosswitz, Julia Alten, Silvia Jenni, Yi-Chien Tsai, Gunnar Cario, Roberta La Starza, Ondrej Hrusak, Andreas E. Kulozik, Olaf Witt, Martin Stanulla, Martin Schrappe, Christian M. Zwaan, Cornelia Eckert, Arend von Stackelberg, Andre Baruchel, Elad Jacoby, Axel Karow, Francesco Ceppi, Beat Bornhauser, Jean-Pierre Bourquin
Journal: Blood (2020)
ANCHOR (OP-104): Melflufen Plus Dexamethasone (dex) and Daratumumab (dara) or Bortezomib (BTZ) in Relapsed/Refractory Multiple Myeloma (RRMM) Refractory to an IMiD and/or a Proteasome Inhibitor (PI) - Updated Efficacy and Safety
Authors: Enrique M. Ocio, Yvonne A. Efebera, Roman Hájek, Miquel Granell, Vladimir Maisnar, Jan Straub, Jean-Richard Eveillard, Lionel Karlin, Vincent Ribrag, María-Victoria Mateos, Albert Oriol, Malin Sydvander, Stefan Norin, Sofia Mannikko, Luděk Pour
Journal: Blood (2020)