tbuckley/cabot-search huggingface dataset:
Errors in Table.
Journal: JAMA (1992)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Impact of Clinical and Biomarker Covariates on the Ability of the Asthma Impairment and Risk Questionnaire (AIRQ®) to Predict Future Exacerbations
Authors: Kevin Murphy, David Beuther, Bradley Chipps, Robert Wise, William McCann, Joan Reibman, Maureen George, Ileen Gilbert, James Eudicone, Hitesh Gandhi, Melissa Ross, Karin Coyne, Robert Zeiger
Journal: Journal of Allergy and Clinical Immunology (2022)
Association Between Screen Time Exposure in Children at 1 Year of Age and Autism Spectrum Disorder at 3 Years of Age
Authors: Megumi Kushima, Reiji Kojima, Ryoji Shinohara, Sayaka Horiuchi, Sanae Otawa, Tadao Ooka, Yuka Akiyama, Kunio Miyake, Hiroshi Yokomichi, Zentaro Yamagata, Michihiro Kamijima, Shin Yamazaki, Yukihiro Ohya, Reiko Kishi, Nobuo Yaegashi, Koichi Hashimoto, Chisato Mori, Shuichi Ito, Zentaro Yamagata, Hidekuni Inadera, Takeo Nakayama, Hiroyasu Iso, Masayuki Shima, Hiroshige Nakamura, Narufumi Suganuma, Koichi Kusuhara, Takahiko Katoh
Journal: JAMA Pediatrics (2022)

<h3>Importance</h3> It is unclear to what extent the duration of screen time in infancy is associated with the subsequent diagnosis of autism spectrum disorder. <h3>Objective</h3> To examine the association between screen time in infancy and the development of autism spectrum disorder at 3 years of age. <h3>Design, Setting, and Participants</h3> This cohort study analyzed data from mother-child dyads in a large birth cohort in Japan. This study included children born to women recruited between January 2011 and March 2014, and data were analyzed in December 2020. The study was conducted by the Japan Environment and Children's Study Group in collaboration with 15 regional centers across Japan. <h3>Exposures</h3> Screen time at 1 year of age. <h3>Main Outcomes and Measures</h3> The outcome variable, children diagnosed with autism spectrum disorder at 3 years of age, was assessed using a questionnaire administered to mothers of the participating children. <h3>Results</h3> A total of 84 030 mother-child dyads were analyzed. The prevalence of children with autism spectrum disorder at 3 years of age was 392 per 100 000 (0.4%), and boys were 3 times more likely to have been diagnosed with autism spectrum disorder than were girls. Logistic regression analysis showed that among boys, when "no screen" was the reference, the adjusted odds ratios were as follows: less than 1 hour, odds ratio, 1.38 (95 % CI, 0.71-2.69;<i>P</i> = .35), 1 hour to less than 2 hours, odds ratio, 2.16 (95 % CI, 1.13-4.14;<i>P</i> = .02), 2 hours to less than 4 hours, odds ratio, 3.48 (95% CI, 1.83-6.65;<i>P</i> &lt; .001), and more than 4 hours, odds ratio, 3.02 (95% CI, 1.44-6.34;<i>P</i> = .04). Among girls, however, there was no association between autism spectrum disorder and screen time. <h3>Conclusions and Relevance</h3> Among boys, longer screen time at 1 year of age was significantly associated with autism spectrum disorder at 3 years of age. With the rapid increase in device usage, it is necessary to review the health effects of screen time on infants and to control excessive screen time.
Computational image features of immune architecture is associated with clinical benefit and survival in gynecological cancers across treatment modalities
Authors: Sepideh Azarianpour, Germán Corredor, Kaustav Bera, Patrick Leo, Pingfu Fu, Paula Toro, Amy Joehlin-Price, Mojgan Mokhtari, Haider Mahdi, Anant Madabhushi
Journal: Journal for ImmunoTherapy of Cancer (2022)

We present a computational approach (ArcTIL) for quantitative characterization of the architecture of tumor-infiltrating lymphocytes (TILs) and their interplay with cancer cells from digitized H&E-stained histology whole slide images and evaluate its prognostic role in three different gynecological cancer (GC) types and across three different treatment types (platinum, radiation and immunotherapy).In this retrospective study, we included 926 patients with GC diagnosed with ovarian cancer (OC), cervical cancer, and endometrial cancer with available digitized diagnostic histology slides and survival outcome information. ArcTIL features quantifying architecture and spatial interplay between immune cells and the rest of nucleated cells (mostly comprised cancer cells) were extracted from the cell cluster graphs of nuclei within the tumor epithelial nests, surrounding stroma and invasive tumor front compartments on H&E-stained slides. A Cox proportional hazards model, incorporating ArcTIL features was fit on the OC training cohort (N=51), yielding an ArcTIL signature. A unique threshold learned from the training set stratified the patients into a low and high-risk group.The seven feature ArcTIL classifier was found to significantly correlate with overall survival in chemotherapy and radiotherapy-treated validation cohorts and progression-free survival in an immunotherapy-treated validation cohort. ArcTIL features relating to increased density of TILs in the epithelium and invasive tumor front were found to be associated with better survival outcomes when compared with those patients with an increased TIL density in the stroma. A statistically significant association was found between the ArcTIL signature and signaling pathways for blood vessel morphogenesis, vasculature development, regulation of cell differentiation, cell-substrate adhesion, biological adhesion, regulation of vasculature development, and angiogenesis.This study reveals that computationally-derived features from the spatial architecture of TILs and tumor cells are prognostic in GCs treated with chemotherapy, radiotherapy, and checkpoint blockade and are closely associated with central biological processes that impact tumor progression. These findings could aid in identifying therapy-refractory patients and further enable personalized treatment decision-making.
Safety and immunogenicity of a ferritin nanoparticle H2 influenza vaccine in healthy adults: a phase 1 trial
Authors: Katherine V. Houser, Grace L. Chen, Cristina Carter, Michelle C. Crank, Thuy A. Nguyen, Maria Claudia Burgos Florez, Nina M. Berkowitz, Floreliz Mendoza, Cynthia Starr Hendel, Ingelise J. Gordon, Emily E. Coates, Sandra Vazquez, Judy Stein, Christopher L. Case, Heather Lawlor, Kevin Carlton, Martin R. Gaudinski, Larisa Strom, Amelia R. Hofstetter, C. Jason Liang, Sandeep Narpala, Christian Hatcher, Rebecca A. Gillespie, Adrian Creanga, Masaru Kanekiyo, Julie E. Raab, Sarah F. Andrews, Yi Zhang, Eun Sung Yang, Lingshu Wang, Kwanyee Leung, Wing-Pui Kong, Alec W. Freyn, Raffael Nachbagauer, Peter Palese, Robert T. Bailer, Adrian B. McDermott, Richard A. Koup, Jason G. Gall, Frank Arnold, John R. Mascola, Barney S. Graham, Julie E. Ledgerwood, Joseph Casazza, Lasonji Holman, Abidemi O. Ola, Pamela Costner, Jennifer Cunningham, Brenda Larkin, Laura Novik, Jamie Saunders, William Whalen, Xiaolin Wang, Aba Mensima Eshun, Alison Taylor, K. C. Cheng, Carolyn Laurencot, Josephine H. Cox, Sandra Sitar, Lam Le, Iris Pittman, Olga Vasilenko, Ro Shauna Rothwell, Galina Yamshchikov, Eugenia Burch, Somia Hickman, Olga Trofymenko, Catina Boyd, Preeti Apte, Cora Trelles Cartagena, Renunda Hicks, Pernell Williams, Zana Blaku, Colin Tran
Journal: Nature Medicine (2022)
Adherence to 2020 to 2025 Dietary Guidelines for Americans and the Risk of New-Onset Female Gout
Authors: Chio Yokose, Natalie McCormick, Na Lu, Amit D. Joshi, Gary Curhan, Hyon K. Choi
Journal: JAMA Internal Medicine (2022)

Female-specific gout data are scarce despite perceived differences from males in its risk factors and disproportionate worsening in disease and comorbidity burden globally. The 2020 to 2025 Dietary Guidelines for Americans recommend multiple healthy eating patterns for prevention of cardiovascular-metabolic outcomes, which may also be relevant to the prevention of female gout.
The 2021 European Alliance of Associations for Rheumatology/American College of Rheumatology points to consider for diagnosis and management of autoinflammatory type I interferonopathies: CANDLE/PRAAS, SAVI and AGS
Authors: Kader Cetin Gedik, Lovro Lamot, Micol Romano, Erkan Demirkaya, David Piskin, Sofia Torreggiani, Laura A Adang, Thais Armangue, Kathe Barchus, Devon R Cordova, Yanick J Crow, Russell C Dale, Karen L Durrant, Despina Eleftheriou, Elisa M Fazzi, Marco Gattorno, Francesco Gavazzi, Eric P Hanson, Min Ae Lee-Kirsch, Gina A Montealegre Sanchez, Bénédicte Neven, Simona Orcesi, Seza Ozen, M Cecilia Poli, Elliot Schumacher, Davide Tonduti, Katsiaryna Uss, Daniel Aletaha, Brian M Feldman, Adeline Vanderver, Paul A Brogan, Raphaela Goldbach-Mansky
Journal: Annals of the Rheumatic Diseases (2022)

Autoinflammatory type I interferonopathies, chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature/proteasome-associated autoinflammatory syndrome (CANDLE/PRAAS), stimulator of interferon genes (STING)-associated vasculopathy with onset in infancy (SAVI) and Aicardi-Goutières syndrome (AGS) are rare and clinically complex immunodysregulatory diseases. With emerging knowledge of genetic causes and targeted treatments, a Task Force was charged with the development of 'points to consider' to improve diagnosis, treatment and long-term monitoring of patients with these rare diseases.Members of a Task Force consisting of rheumatologists, neurologists, an immunologist, geneticists, patient advocates and an allied healthcare professional formulated research questions for a systematic literature review. Then, based on literature, Delphi questionnaires and consensus methodology, 'points to consider' to guide patient management were developed.The Task Force devised consensus and evidence-based guidance of 4 overarching principles and 17 points to consider regarding the diagnosis, treatment and long-term monitoring of patients with the autoinflammatory interferonopathies, CANDLE/PRAAS, SAVI and AGS.These points to consider represent state-of-the-art knowledge to guide diagnostic evaluation, treatment and management of patients with CANDLE/PRAAS, SAVI and AGS and aim to standardise and improve care, quality of life and disease outcomes.
PULMONARY ASPIRATION OF PARTICULATE MATTER, NORMALLY AND DURING ANESTHESIA
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Cancer Control Outcomes Following Focal Therapy Using High-intensity Focused Ultrasound in 1379 Men with Nonmetastatic Prostate Cancer: A Multi-institute 15-year Experience
Authors: Deepika Reddy, Max Peters, Taimur T. Shah, Marieke van Son, Mariana Bertoncelli Tanaka, Philipp M. Huber, Derek Lomas, Arnas Rakauskas, Saiful Miah, David Eldred-Evans, Stephanie Guillaumier, Feargus Hosking-Jervis, Ryan Engle, Tim Dudderidge, Richard G. Hindley, Amr Emara, Raj Nigam, Neil McCartan, Massimo Valerio, Naveed Afzal, Henry Lewi, Clement Orczyk, Chris Ogden, Iqbal Shergill, Raj Persad, Jaspal Virdi, Caroline M. Moore, Manit Arya, Mathias Winkler, Mark Emberton, Hashim U. Ahmed
Journal: European Urology (2022)
Improving Understanding of Food Allergy Management and Potential Drivers of Socioeconomic Disparities in Food Allergy Outcomes via a Large Community-Based Survey
Authors: Jennaveve Yost, Anita Roach, Isabel Galic, Justine Asante, Marie Concklin-Malloy, Ososese Enaholo, Ruchi Gupta, Christopher Warren
Journal: Journal of Allergy and Clinical Immunology (2022)
The effectiveness and cost-effectiveness of screening for active tuberculosis among migrants in the EU/EEA: a systematic review
Authors: Christina Greenaway, Manish Pareek, Claire-Nour Abou Chakra, Moneeza Walji, Iuliia Makarenko, Balqis Alabdulkarim, Catherine Hogan, Ted McConnell, Brittany Scarfo, Robin Christensen, Anh Tran, Nick Rowbotham, Teymur Noori, Marieke J van der Werf, Kevin Pottie, Alberto Matteelli, Dominik Zenner, Rachael L Morton
Journal: Eurosurveillance (2018)

Background : The foreign-born population make up an increasing and large proportion of tuberculosis (TB) cases in European Union/European Economic Area (EU/EEA) low-incidence countries and challenge TB elimination efforts. Methods : We conducted a systematic review to determine effectiveness (yield and performance of chest radiography (CXR) to detect active TB, treatment outcomes and acceptance of screening) and a second systematic review on cost-effectiveness of screening for active TB among migrants living in the EU/EEA. Results : We identified six systematic reviews, one report and three individual studies that addressed our aims. CXR was highly sensitive (98%) but only moderately specific (75%). The yield of detecting active TB with CXR screening among migrants was 350 per 100,000 population overall but ranged widely by host country (110–2,340), migrant type (170–1,192), TB incidence in source country (19–336) and screening setting (220–1,720). The CXR yield was lower (19.6 vs 336/100,000) and the numbers needed to screen were higher (5,076 vs 298) among migrants from source countries with lower TB incidence (≤ 50 compared with ≥ 350/100,000). Cost-effectiveness was highest among migrants originating from high (&gt; 120/100,000) TB incidence countries. The foreign-born had similar or better TB treatment outcomes than those born in the EU/EEA. Acceptance of CXR screening was high (85%) among migrants. Discussion : Screening programmes for active TB are most efficient when targeting migrants from higher TB incidence countries. The limited number of studies identified and the heterogeneous evidence highlight the need for further data to inform screening programmes for migrants in the EU/EEA.
THE TWENTY-SECOND ANNUAL MEETING OF THE AMERICAN ACADEMY OF MEDICINE.
Journal: JAMA (1897)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Posters
Authors: D. Geber, R. Pizov, L. A. Eidelman, N. Adi, C. L. Sprung, E. Eleftheriadis, K. Kotzampassi, S. Heliadis, G. Papageorgiou, A. Dimitriadou, L. Brazzi, O. Chiara, M. Segala, M. G. Turconi, P. Pelosi, D. Volpi, I. Lantieri, M. Imhoff, Ch. Mork, D. Berg, J. H. Lehner, D. Löhlein, M. Fae, E. Bernardi, M. Caporaloni, A. Dante, I. Riganello, M. Nastasi, G. Martinelli, Y. Watanabe, K. Kumon, N. Yahagi, M. Haruna, H. Hayashi, J. Matsui, Y. Terada, Y. Eguchi, R. Mandai, S. Nosaka, R. Tabata, H. Sakumoto, O. Takehiro, S. Uno, K. Ozawa, O. Väisänen, I. Parviainen, M. Hippeläinen, E. Berg, H. Hendolin, E. Ruokonen, J. Takala, M. A. Romera, C. Chamorro, J. M. Borrallo, R. Ruiz de Luna, J. L. M. Melgar, E. Dominguez de Villota, F. Turani, C. Ceraso, M. Dauri, E. Zupancich, M. Pierri, A. Penta, F. Sabato, G. Kostopanagiotou, K. Theodoraki, K. Mavrantonis, N. Heaton, D. Potter, J. Papadimitriou, C. G. Krenn, W. Kneifel, A. Baker, H. Tschemich, H. Steltzer, J. Creteur, D. De Backer, O. Noordally, R. J. Kahn, J. L. Vincent, H. Zhang, S. Cherkaoui, R. De Jough, I. A. Mitchell, T. C. N. Northfield, E. D. Bennett, B. De Jonghe, C. Cheval, B. Misset, M. Garrouste, L. Montuclard, V. Sitruk, J. Carlet, P. F. Laterre, B. Espeel, D. Schmidlin, P. Basset, A. Saliez, L. Lambotte, M. S. Reynaert, P. Gianello, E. Danse, J. P. Pelgrim, C. Guinotte, J. Etienne
Journal: Intensive Care Medicine (1996)
Abstract 265: Extracorporeal Cardiopulmonary Resuscitation for Acute Aortic Dissection During Cardiac Arrest: A Nationwide Retrospective Observational Study
Authors: Takayuki Ogura, Hiroyuki Ohbe, Hideo Yasunaga
Journal: Circulation (2020)

Aim: Acute aortic dissection has been considered a contraindication for extracorporeal cardiopulmonary resuscitation (ECPR). However, studies are lacking regarding the epidemiology and effectiveness of ECPR for this condition. We aimed to examine whether ECPR for acute aortic dissection during cardiac arrest is effective or not. Methods: Using the Japanese Diagnosis Procedure Combination inpatient database from July 2010 to March 2018, we identified all emergently hospitalized adults who received ECPR on the day of admission. ECPR was defined as receiving both chest compressions and percutaneous extracorporeal membrane oxygenation on the day of hospital admission. In-hospital mortality and neurological outcomes were compared between patients with and without acute aortic dissection. We also calculated the incremental cost-effectiveness ratio of ECPR for acute aortic dissection. Results: We identified 10,238 patients who received ECPR on the day of admission. Of these, 398 patients (3.9%) had acute aortic dissection. In-hospital mortality was 98% in the acute aortic dissection group and 79% in the non-acute aortic dissection group. Seven patients (1.8%) in the acute aortic dissection group survived to discharge after ECPR; of these, six patients had good neurological outcomes at discharge. The incremental cost-effectiveness ratio of ECPR for patients with acute aortic dissection was estimated at 159,337 US dollars per quality-adjusted life year gained. Conclusion: ECPR successfully rescued a small number of acute aortic dissection patients with cardiac arrest; however, the cost burden of ECPR for acute aortic dissection patients was unacceptably high.
Response to Open Peer Commentaries on “Developing a Reflexive, Anticipatory, and Deliberative Approach to Unanticipated Discoveries: Ethical Lessons from iBlastoids”
Authors: Rachel A. Ankeny, Megan J. Munsie, Joan Leach
Journal: The American Journal of Bioethics (2022)

This article refers to:Developing a Reflexive, Anticipatory, and Deliberative Approach to Unanticipated Discoveries: Ethical Lessons from iBlastoidsA RAD Approach to iBlastoids with a Moral Principle of ComplexityWhy iBlastoids (Embryo-like Structures) Do Not Rise Significant Ethical IssuesAmplifying the Call for Anticipatory GovernanceGovernance of Emerging Biotechnologies: Lessons from Two Chinese CasesAnticipatory Governance and Foresight in Regulating for UncertaintyHow Ethics Can Better Anticipate the Consequences of Emerging Biotechnologies
Patients in complete remission after R-CHOP(-like) therapy for diffuse large B-cell lymphoma have limited excess use of health care services in Denmark
Authors: Lasse Hjort Jakobsen, Andreas Kiesbye Øvlisen, Marianne Tang Severinsen, Joachim Bæch, Kristian Hay Kragholm, Ingrid Glimelius, Anne Ortved Gang, Judit Mészáros Jørgensen, Henrik Frederiksen, Christian Bjørn Poulsen, Michael Roost Clausen, Per Trøllund Pedersen, Robert Schou Pedersen, Christian Torp-Pedersen, Sandra Eloranta, Tarec Christoffer El-Galaly
Journal: Blood Cancer Journal (2022)

For most patients with newly diagnosed diffuse large B-cell lymphoma (DLBCL), R-CHOP immunochemotherapy leads to complete remission and 60-70% of patients remain progression-free after 5 years. Given a median age of 65, it is relevant to disentangle how DLBCL and DLBCL therapy influence health care use among the survivors. In this nationwide study, the health care use among Danish DLBCL patients diagnosed in 2007-2015, who achieved complete remission after R-CHOP(-like) therapy, was explored and compared to matched comparators from the Danish general population. The post-remission 5-year risk of hospitalization was significantly higher among DLBCL survivors (55%) compared to matched comparators (49%, P < 0.001). DLBCL survivors had on average 10.3 (9.3-11.3) inpatient bed days within 5 years of response evaluation, whereas matched comparators had 8.4 (7.9-8.8). The rate of outpatient visits was also significantly higher(excluding routine follow-up visits, incidence rate ratio, 1.3, P < 0.001), but translated into only a very small absolute difference of <1 outpatient visits within 5 years between DLBCL survivors (4.2 visits, 95% CI, 4.0-4.4) and matched comparators (3.8 visits, 95% CI, 3.7-3.9). In conclusion, DLBCL survivors have an increased incidence of hospital visits due to a wide range of conditions, but in absolute terms the excess use of health care services in DLBCL survivors was small.