tbuckley/cabot-search huggingface dataset:
Hemopneumothorax detection through the process of artificial evolution - a feasibility study
Authors: Adir Sommer, Noy Mark, Gavriel D. Kohlberg, Rafi Gerasi, Linn Wagnert Avraham, Ruth Fan-Marko, Arik Eisenkraft, Dean Nachman
Journal: Military Medical Research (2021)

Abstract Background Tension pneumothorax is one of the leading causes of preventable death on the battlefield. Current prehospital diagnosis relies on a subjective clinical impression complemented by a manual thoracic and respiratory examination. These techniques are not fully applicable in field conditions and on the battlefield, where situational and environmental factors may impair clinical capabilities. We aimed to assemble a device able to sample, analyze, and classify the unique acoustic signatures of pneumothorax and hemothorax. Methods Acoustic data was obtained with simultaneous use of two sensitive digital stethoscopes from the chest wall of an ex-vivo porcine model. Twelve second samples of acoustic data were obtained from the in-house assembled digital stethoscope system during mechanical ventilation. The thoracic cavity was injected with increasing volumes of 200, 400, 600, 800, and 1000 ml of air or saline to simulate pneumothorax and hemothorax, respectively. The data was analyzed using a multi-objective genetic algorithm that was used to develop an optimal mathematical detector through the process of artificial evolution, a cutting-edge approach in the artificial intelligence discipline. Results The in-house assembled dual digital stethoscope system and developed genetic algorithm achieved an accuracy, sensitivity and specificity ranging from 64 to 100%, 63 to 100%, and 63 to 100%, respectively, in classifying acoustic signal as associated with pneumothorax or hemothorax at fluid injection levels of 400 ml or more, and regardless of background noise. Conclusions We present a novel, objective device for rapid diagnosis of potentially lethal thoracic injuries. With further optimization, such a device could provide real-time detection and monitoring of pneumothorax and hemothorax in battlefield conditions.
FULMINANT MYOCARDITIS AND MULTISYSTEM INFLAMMATORY SYNDROME IN CHILDREN, IN THE LIGHT OF CORONA VIRUS
Authors: Vijay Pratap Singh, Mousa Thalji, Swaiman Singh, Hamza Hafeez, Amandeep Sekhon, Mohammed Faizan Ul Haq, Kashyap Kela
Journal: Journal of the American College of Cardiology (2021)
FEASIBILITY AND SAFETY OF DRUG-ELUTING STENT IMPLANTATION IN PATIENTS WITH END-STAGE LIVER DISEASE PRIOR TO LIVER TRANSPLANTATION
Authors: Thalys Sampaio Rodrigues, Anoop Ninan Koshy, Paul J. Gow, David J. Clark, Mark Horrigan, Omar Farouque
Journal: Journal of the American College of Cardiology (2021)
Re: Evaluation of Patient- and Surgeon-specific Variations in Patient-reported Urinary Outcomes 3 Months After Radical Prostatectomy from a Statewide Improvement Collaborative
Authors: Lara Rodríguez Sánchez, Alexandre Mottrie, Markus Graefen, Xavier Cathelineau, Alberto Breda, Rafael Sanchez-Salas
Journal: European Urology (2021)
Targeted inhibition of SIRT6 via engineered exosomes impairs tumorigenesis and metastasis in prostate cancer
Authors: Qing Han, Qian Rueben Xie, Fan Li, Yirui Cheng, Tingyu Wu, Yanshuang Zhang, Xin Lu, Alice S T Wong, Jianjun Sha, Weiliang Xia
Journal: Theranostics (2021)

The treatment for metastatic castration-resistant prostate cancer patients remains a great challenge in the clinic and continuously demands discoveries of new targets and therapies. Here, we assess the function and therapeutic value of SIRT6 in metastatic castration-resistant prostate cancer.
Abstract 14249: Proteasome Priming by Cyclic Amp Signaling Protects Stressed Hearts in Mice
Authors: Penglong Wu, Nirmal Parajuli, Megan Lewno, Jinbao Liu, Xuejun Wang
Journal: Circulation (2019)

Introduction: Measures to correct proteasome (Psm) impairment promise to benefit heart failure treatment but the search for such measures requires better understanding how Psm activity is regulated...
In South Africa, a 2-dose Oxford/AZ vaccine did not prevent mild to moderate COVID-19 (cases mainly B.1.351 variant)
Authors: Neal Irfan, Zain Chagla
Journal: Annals of Internal Medicine (2021)

Source CitationMadhi SA, Baillie V, Cutland CL, et al. Efficacy of the ChAdOx1 nCoV-19 Covid-19 vaccine against the B.1.351 variant. N Engl J Med. 2021. [Epub ahead of print.] https://pubmed.ncbi.nlm.nih.gov/33725432/AbstractClinical Impact RatingsGIM/FP/GP: Emergency Med: Hospitalists:
GENDER-BASED OUTCOMES OF CORONARY BIFURCATION STENTING
Authors: Mohammed Osman, Yasir Abdul Ghaffar, Khansa Osman, Babikir Kheiri, Mohamed Maali Mohamed, Mohammad Akram Kawsara, Sudarshan Balla, Anthony Roda-Renzelli, Ramesh Daggubati
Journal: Journal of the American College of Cardiology (2021)
BPA, Parabens, and Phthalates in Relation to Endometrial Cancer Risk: A Case–Control Study Nested in the Multiethnic Cohort
Authors: Danja Sarink, Adrian A. Franke, Kami K. White, Anna H. Wu, Iona Cheng, Brandon Quon, Loïc Le Marchand, Lynne R. Wilkens, Herbert Yu, Melissa A. Merritt
Journal: Environmental Health Perspectives (2021)
Magnetism-mediated targeting hyperthermia-immunotherapy in “cold” tumor with CSF1R inhibitor
Authors: Yuefei Fang, Yang He, Canhao Wu, Meng Zhang, Zeyun Gu, Jiaxin Zhang, Ergang Liu, Qin Xu, Akmal M. Asrorov, Yongzhuo Huang
Journal: Theranostics (2021)

Background: Immunotherapy has profoundly changed the landscape of cancer management and represented the most significant breakthrough. Yet, it is a formidable challenge that the majority of cancers - the so-called "cold" tumors - poorly respond to immunotherapy. To find a general immunoregulatory modality that can be applied to a broad spectrum of cancers is an urgent need. Methods: Magnetic hyperthermia (MHT) possesses promise in cancer therapy. We develop a safe and effective therapeutic strategy by using magnetism-mediated targeting MHT-immunotherapy in "cold" colon cancer. A magnetic liposomal system modified with cell-penetrating TAT peptide was developed for targeted delivery of a CSF1R inhibitor (BLZ945), which can block the CSF1-CSF1R pathway and reduce M2 macrophages. The targeted delivery strategy is characterized by its magnetic navigation and TAT-promoting intratumoral penetration. Results: The liposomes (termed TAT-BLZmlips) can induce ICD and cause excessive CRT exposure on the cell surface, which transmits an "eat-me" signal to DCs to elicit immunity. The combination of MHT and BLZ945 can repolarize M2 macrophages in the tumor microenvironment to relieve immunosuppression, normalize the tumor blood vessels, and promote T-lymphocyte infiltration. The antitumor effector CD8+ T cells were increased after treatment. Conclusion: This work demonstrated that TAT-BLZmlips with magnetic navigation and MHT can remodel tumor microenvironment and activate immune responses and memory, thus inhibiting tumor growth and recurrence.
Metabolic Syndrome Is Associated With More Pronounced Impairment of Left Ventricle Geometry and Function in Patients With Calcific Aortic Stenosis
Authors: Anik Pagé, Jean G. Dumesnil, Marie-Annick Clavel, Kwan L. Chan, Koon K. Teo, James W. Tam, Patrick Mathieu, Jean-Pierre Després, Philippe Pibarot
Journal: Journal of the American College of Cardiology (2010)
WORSE OUTCOMES IN INDIVIDUALS WITH OBESITY UNDERGOING LEFT VENTRICULAR ASSIST DEVICE IMPLANTATION: A LONGITUDINAL INTERMACS STUDY
Authors: Katherine Clark, Avirup Guha, Evangelos Oikonomou, Ania M. Jastreboff, Cesar Caraballo, Neal L. Weintraub, Tariq Ahmad, Eric Velazquez, P. Elliott Miller, Nihar Desai
Journal: Journal of the American College of Cardiology (2021)
The therapeutic potential of inorganic polyphosphate: A versatile physiological polymer to control coronavirus disease (COVID-19)
Authors: Hadrian Schepler, Xiaohong Wang, Meik Neufurth, Shunfeng Wang, Heinz C. Schröder, Werner E. G. Müller
Journal: Theranostics (2021)

The pandemic caused by the novel coronavirus SARS-CoV-2 is advancing rapidly. In particular, the number of severe courses of the disease is still dramatically high. An efficient drug therapy that helps to improve significantly the fatal combination of damages in the airway epithelia, in the extensive pulmonary microvascularization and finally multiorgan failure, is missing. The physiological, inorganic polymer, polyphosphate (polyP) is a molecule which could prevent the initial phase of the virus life cycle, the attachment of the virus to the target cells, and improve the epithelial integrity as well as the mucus barrier.
CHARACTERISTICS, MANAGEMENT AND BLOOD PRESSURE CONTROL IN PATIENTS WITH HYPERTENSION TAKING 3 OR MORE ANTIHYPERTENSIVE MEDICATIONS
Authors: Ellen S. O’Brien, Eric M. Ammann, Dejan Milentijevic, Akshay A. Kharat, Darren A. Talbot, Nabil S. Andrawis
Journal: Journal of the American College of Cardiology (2021)
Metformin facilitates mesenchymal stem cell-derived extracellular nanovesicles release and optimizes therapeutic efficacy in intervertebral disc degeneration
Authors: Zhiwei Liao, Shuai Li, Saideng Lu, Hui Liu, Gaocai Li, Liang Ma, Rongjin Luo, Wencan Ke, Bingjin Wang, Qian Xiang, Yu Song, Xiaobo Feng, Yukun Zhang, Xinghuo Wu, Wenbin Hua, Cao Yang
Journal: Biomaterials (2021)
Digital Frozen Sections with Fluorescence Confocal Microscopy During Robot-assisted Radical Prostatectomy: Surgical Technique
Authors: Bernardo Rocco, Luca Sarchi, Simone Assumma, Alessia Cimadamore, Rodolfo Montironi, Luca Reggiani Bonetti, Filippo Turri, Cosimo De Carne, Stefano Puliatti, Antonino Maiorana, Giovanni Pellacani, Salvatore Micali, Giampaolo Bianchi, Maria Chiara Sighinolfi
Journal: European Urology (2021)
ACUTE ST-ELEVATION MYOCARDIAL INFARCTION IN A 26-YEAR-OLD MALE: A CASE OF UNDIAGNOSED DIABETES AND HYPERTRIGLYCERIDEMIA
Authors: Sachit Singal, Anshul Parulkar, Sanchita Singal Parulkar, Christopher Tuohy, Shafiq Mamdani
Journal: Journal of the American College of Cardiology (2021)
Covid-19: US authorises Johnson and Johnson vaccine again, ending pause in rollout
Authors: Janice Hopkins Tanne
Journal: BMJ (2021)

The US Food and Drug Administration approved the Johnson & Johnson (J&J) single dose covid-19 vaccine on 23 April after a cautionary 10 day pause to consider the risk of blood clots.Administration of the vaccine began immediately but came with a handout warning of the risk of clots in women under 50. 1 The vaccine is made by J&J's subsidiary, Janssen.Janet Woodcock, acting FDA commissioner, said at a press conference, "We have concluded that the known and potential benefit of the . . .vaccine outweigh[s] its known and potential risks in individuals 18 years of age and older."Rochelle Walensky, director of the Centers for Disease Control and Prevention (CDC), said that she supported the FDA's decision.
Surgical ablation of the right greater splanchnic nerve for the treatment of heart failure with preserved ejection fraction: first‐in‐human clinical trial
Authors: Filip Málek, Piotr Gajewski, Robert Zymliński, Dariusz Janczak, Mariusz Chabowski, Marat Fudim, Tomas Martinca, Petr Neužil, Jan Biegus, Martin Mates, Andreas Krüger, Ivo Skalský, Anisha Bapna, Zoar J. Engelman, Piotr P. Ponikowski
Journal: European Journal of Heart Failure (2021)
CATMoS: Collaborative Acute Toxicity Modeling Suite
Authors: Kamel Mansouri, Agnes L. Karmaus, Jeremy Fitzpatrick, Grace Patlewicz, Prachi Pradeep, Domenico Alberga, Nathalie Alepee, Timothy E.H. Allen, Dave Allen, Vinicius M. Alves, Carolina H. Andrade, Tyler R. Auernhammer, Davide Ballabio, Shannon Bell, Emilio Benfenati, Sudin Bhattacharya, Joyce V. Bastos, Stephen Boyd, J.B. Brown, Stephen J. Capuzzi, Yaroslav Chushak, Heather Ciallella, Alex M. Clark, Viviana Consonni, Pankaj R. Daga, Sean Ekins, Sherif Farag, Maxim Fedorov, Denis Fourches, Domenico Gadaleta, Feng Gao, Jeffery M. Gearhart, Garett Goh, Jonathan M. Goodman, Francesca Grisoni, Christopher M. Grulke, Thomas Hartung, Matthew Hirn, Pavel Karpov, Alexandru Korotcov, Giovanna J. Lavado, Michael Lawless, Xinhao Li, Thomas Luechtefeld, Filippo Lunghini, Giuseppe F. Mangiatordi, Gilles Marcou, Dan Marsh, Todd Martin, Andrea Mauri, Eugene N. Muratov, Glenn J. Myatt, Dac-Trung Nguyen, Orazio Nicolotti, Reine Note, Paritosh Pande, Amanda K. Parks, Tyler Peryea, Ahsan H. Polash, Robert Rallo, Alessandra Roncaglioni, Craig Rowlands, Patricia Ruiz, Daniel P. Russo, Ahmed Sayed, Risa Sayre, Timothy Sheils, Charles Siegel, Arthur C. Silva, Anton Simeonov, Sergey Sosnin, Noel Southall, Judy Strickland, Yun Tang, Brian Teppen, Igor V. Tetko, Dennis Thomas, Valery Tkachenko, Roberto Todeschini, Cosimo Toma, Ignacio Tripodi, Daniela Trisciuzzi, Alexander Tropsha, Alexandre Varnek, Kristijan Vukovic, Zhongyu Wang, Liguo Wang, Katrina M. Waters, Andrew J. Wedlake, Sanjeeva J. Wijeyesakere, Dan Wilson, Zijun Xiao, Hongbin Yang, Gergely Zahoranszky-Kohalmi, Alexey V. Zakharov, Fagen F. Zhang, Zhen Zhang, Tongan Zhao, Hao Zhu, Kimberley M. Zorn, Warren Casey, Nicole C. Kleinstreuer
Journal: Environmental Health Perspectives (2021)

la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d'enseignement et de recherche français ou étrangers, des laboratoires publics ou privés.
Covid-19: Africa scrambles to increase genomic testing capacity as variants spread
Authors: Abdullahi Tsanni
Journal: BMJ (2021)

Patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency are not represented in clinical trials for heart failure. Moreover, many of the recommended medications can cause haemolysis in this group of patients. We present the case of a 71-year-old woman with G6PD deficiency admitted for acute non-ischemic heart failure with reduced ejection fraction. Our experience showed that a combination of ethacrynic acid and spironolactone is safe and effective for relief of volume overload in this group of patients. Studies are needed to determine whether the morbidity and mortality benefits of established heart failure regimens extend to patients with G6PD deficiency.
Tertiary lymphoid organs are associated with the progression of kidney damage and regulated by interleukin-17A
Authors: Ran Luo, Yichun Cheng, Dan Chang, Tingting Liu, Liu Liu, Guangchang Pei, Nanhui Zhang, Zufeng Wang, Kanglin Guo, Wei Chen, Ming Li, Li Fan, Chunxiu Zhang, Yueqiang Li, Wei Dai, Meiying Zuo, Yulin Xu, Ying Yao, Shuwang Ge, Gang Xu
Journal: Theranostics (2020)

Background: Tertiary lymphoid organs (TLOs) occur after multiple chronic kidney injuries. interleukin-17A (IL-17A) has been reported to associate with the development of TLOs in inflammatory diseases. However, regulation of the renal TLOs and its clinical significance to the pathogenesis of chronic kidney injury are unknown. Methods: To evaluate the clinical significance and regulation of renal TLOs, we analyzed the progression of patients with kidney damage based on the existence and absence of TLOs in a larger multicenter cohort. We also blocked the recruitment of lymphocyte cells into the kidney by FTY720 (fingolimod) in vivo. Besides, we used aged IL-17A genetic knocked out mice and IL-17A-neutralizing antibody to explore the role of IL-17A in renal TLOs formation. Results: We demonstrated that renal TLOs of IgA nephropathy patients were associated with disease severity and were independent risk factors for renal progression after adjustment for age, sex, mean arterial pressure, proteinuria and, baseline eGFR and MEST-C score, especially in the early stage. Plasma levels of TLO-related chemokines CXCL13, CCL19, and CCL21 were higher in patients with renal TLOs. Inhibiting the formation of renal TLOs by FTY720 could reduce the intrarenal inflammation and fibrosis, and early intervention was found to be more effective. IL-17A was increased in renal TLOs models, and genetic depletion of IL-17A or treatment with anti-IL-17A antibody resulted in a marked reduction of the TLOs formation as well as alleviation of renal inflammation and fibrosis. Conclusion: These results indicate that TLOs are associated with the progression of kidney damage and regulated by IL-17A and may be effective targets for the treatment of kidney damage.
INFECTIVE ENDOCARDITIS AND AORTIC PERIVALVULAR ABSCESS - SEVERE AND RARE COMPLICATIONS AFTER TAVR
Authors: Hector A. Oliveras Cordero, Dahima Cintrón, Erica Otero-Cardenas, Alejandro Quilichini, Hilton Franqui-Rivera
Journal: Journal of the American College of Cardiology (2021)
THE SGLT2 INHIBITOR EMPAGLIFLOZIN REDUCES TISSUE SODIUM CONTENT IN PATIENTS WITH CHRONIC HEART FAILURE
Authors: Julie Kolwelter, Dennis Kannenkeril, Peter Linz, Susanne Jung, Armin M. Nagel, Agnes Bosch, Christian Ott, Peter Bramlage, Michael Uder, Stephan Achenbach, Roland Schmieder
Journal: Journal of the American College of Cardiology (2021)
Fetal Hemoglobin Induction with Forced Chromatin Looping in Gene-Modified Erythroid Cells Differentiated from Rhesus Hematopoietic Progenitor Cells
Authors: Selami Demirci, Saurabh Bhardwaj, Naoya Uchida, Juan J. Haro Mora, Byoung Y. Ryu, Gerd A. Blobel, John F Tisdale
Journal: Blood (2017)
IMPACT OF INTENSIVE CARDIAC REHABILITATION VS TRADITIONAL CARDIAC REHABILITATION ON DIET QUALITY AND CARDIOVASCULAR HEALTH MEASURES
Authors: Fatima Lakhani, Susan B. Racette, Elena Deych, Lauren Park, Kristin M. McKenzie, Dotti Durbin, Jennifer Jonagan, Tessa Carson, Nidhi Talpade, Michael W. Rich, Lisa de las Fuentes, Linda R. Peterson
Journal: Journal of the American College of Cardiology (2021)
IMPACT OF HIV INFECTION ON THE OUTCOMES OF HOSPITALIZED PATIENTS WITH ACUTE DECOMPENSATED HEART FAILURE: ANALYSIS OF NATIONAL INPATIENT SAMPLE
Authors: Muhammad Usman Almani, Muhammad Usman, Cyra-Yoonsun Kang, Emmanuel Akuna, Iriagbonse Rotimi Asemota, Mahmoud Elbermawy, Raquel Soon-Shiong, Dimeji Williams, Smriti Khanal, Bharosa Sharma, John H. Stroger
Journal: Journal of the American College of Cardiology (2021)
COMPARISON OF GRACE SCORE CHA2DS2-VASC SCORE IN PREDICTING ALL-CAUSE MORTALITY AMONG PATIENTS WITH ATRIAL FIBRILLATION UNDERGOING PERCUTANEOUS CORONARY INTERVENTION
Authors: Ziwei Xi, Hong Qiu, Tingting Guo, Yong Wang, Jianan Li, Yang Li, Jianfeng Zheng, Kefei Dou, Weixian Yang, Shubin Qiao, Bo Xu, YueJin Yang, Runlin Gao
Journal: Journal of the American College of Cardiology (2021)
Re: Eduard Roussel, Giovanni Tasso, Riccardo Campi, et al. Surgical Management and Outcomes of Renal Tumors Arising from Horseshoe Kidneys: Results from an International Multicenter Collaboration. Eur Urol 2021;79:133–40
Authors: Kunlin Yang, Xuesong Li, Liqun Zhou
Journal: European Urology (2021)
Global Prevalence of Diabetic Retinopathy and Projection of Burden through 2045
Authors: Zhen Ling Teo, Yih-Chung Tham, Marco Yu, Miao Li Chee, Tyler Hyungtaek Rim, Ning Cheung, Mukharram M. Bikbov, Ya Xing Wang, Yating Tang, Yi Lu, Ian Y. Wong, Daniel Shu Wei Ting, Gavin Siew Wei Tan, Jost B. Jonas, Charumathi Sabanayagam, Tien Yin Wong, Ching-Yu Cheng
Journal: Ophthalmology (2021)
EFFECTS OF ALIROCUMAB ON CARDIOVASCULAR OUTCOMES IN PATIENTS WITH PREVIOUS MYOCARDIAL INFARCTION: SUBANALYSIS FROM THE ODYSSEY OUTCOMES TRIAL
Authors: Chern-En Chiang, Gregory Schwartz, Yedid Elbez, Deepak Bhatt, Vera Bittner, Rafael Diaz, Andrejs Erglis, Shaun Goodman, Emil Hagstrom, Robert Harrington, Johan Wouter Jukema, Evangelos Liberopoulos, Megan Loy, Robert Pordy, Michael Szarek, Harvey D. White, Andreas Zeiher, Tabassome Simon, Philippe Gabriel Steg
Journal: Journal of the American College of Cardiology (2021)
AGE OF DIAGNOSIS OF PERIPHERAL ARTERY DISEASE AND CARDIOVASCULAR OUTCOMES
Authors: Daniel Sykora, Marlene E. Girardo, Lana Matti, Shubhang K. Bhatt, Andrew Tseng, Justin Shipman, David A. Liedl, Paul Wennberg, Fadi Shamoun
Journal: Journal of the American College of Cardiology (2021)
Programmed death ligand‐1 regulates angiogenesis and metastasis by participating in the c‐JUN/VEGFR2 signaling axis in ovarian cancer
Authors: Yufei Yang, Lingfang Xia, Yong Wu, Hongyu Zhou, Xin Chen, Haoran Li, Midie Xu, Zihao Qi, Ziliang Wang, Huizhen Sun, Xi Cheng
Journal: Cancer Communications (2021)

Abstract Background Although programmed cell death‐ligand 1 (PD‐L1) plays a well‐known function in immune checkpoint response by interacting with programmed cell death‐1 (PD‐1), the cell‐intrinsic role of PD‐L1 in tumors is still unclear. Here, we explored the molecular regulatory mechanism of PD‐L1 in the progression and metastasis of ovarian cancer. Methods Immunohistochemistry of benign tissues and ovarian cancer samples was performed, followed by migration, invasion, and angiogenesis assays in PD‐L1‐knockdown ovarian cancer cells. Immunoprecipitation, mass spectrometry, and chromatin immunoprecipitation were conducted along with zebrafish and mouse experiments to explore the specific functions and mechanisms of PD‐L1 in ovarian cancer. Results Our results showed that PD‐L1 induced angiogenesis, which further promoted cell migration and invasion in vitro and in vivo of ovarian cancer. Mechanistically, PD‐L1 was identified to directly interact with vascular endothelial growth factor receptor‐2 (VEGFR2) and then activated the FAK/AKT pathway, which further induced angiogenesis and tumor progression, leading to poor prognosis of ovarian cancer patients. Meanwhile, PD‐L1 was found to be regulated by the oncogenic transcription factor c‐JUN at the transcriptional level, which enhanced the expression of PD‐L1 in ovarian cancer. Furthermore, we demonstrated that PD‐L1 inhibitor durvalumab, combined with the antiangiogenic drug, apatinib, could enhance the effect of anti‐angiogenesis and the inhibition of cell migration and invasion. Conclusion Our results demonstrated that PD‐L1 promoted the angiogenesis and metastasis of ovarian cancer by participating in the c‐JUN/VEGFR2 signaling axis, suggesting that the combination of PD‐L1 inhibitor and antiangiogenic drugs may be considered as a potential therapeutic approach for ovarian cancer patients.
PERFORMANCE OF GUIDELINE-BASED ALGORITHMS FOR THE ECHOCARDIOGRAPHIC ASSESSMENT OF PATIENTS WITH CLINICALLY-PROVEN BIO PROSTHETIC AORTIC VALVE DYSFUNCTION
Authors: Aslannif Roslan, Jwan Naser, Cristina Pislaru, Mackram Eleid, William Miranda, Kevin Greason, Fletcher Miller, Patricia Pellikka, Vuyisile Nkomo, Sorin Pislaru
Journal: Journal of the American College of Cardiology (2021)
Gel immersion endoscopic submucosal dissection using a novel gel product for a duodenal epithelial tumor
Authors: Tomoaki Tashima, Kazuya Miyaguchi, Rie Terada, Yumi Mashimo, Yuki Tanisaka, Tomonori Kawasaki, Shomei Ryozawa
Journal: Endoscopy (2021)

Endoscopic submucosal dissection (ESD) for duodenal epithelial tumors is technically difficult, with high risks of perforation and bleeding [1]. Therefore, the development of a safe and reliable endoscopic resection method is warranted for these tumors.
INTRACORONARY INFUSION AT REPERFUSION OF THE POLYMER PPO-16 REDUCES INFARCT SIZE IN A PORCINE MODEL OF ACUTE ANTERIOR MYOCARDIAL INFARCTION
Authors: Marinos Kosmopoulos, Adelyn Crabtree, Adrian Ripeckyj, Frank S. Bates, Benjamin J. Hackel, Joseph M. Metzger, Demetris Yannopoulos
Journal: Journal of the American College of Cardiology (2021)
HIGHEST RISK FOR POST-PCI ISCHEMIC EVENTS OCCURRENCES IN AFRICAN AMERICAN WOMEN: A COMMUNITY HOSPITAL EXPERIENCE
Authors: Paul A. Gurbel, Amit Rout, Saroj Timilsina, Abigail Chan, Marko Novakovic, Naval Walia, Kevin Bliden, Sahib Singh, Udaya Tantry
Journal: Journal of the American College of Cardiology (2021)
CLINICAL IMPLICATIONS OF POSTOPERATIVE ATRIAL FIBRILLATION IN HYPERTROPHIC CARDIOMYOPATHY PATIENTS UNDERGOING SURGICAL MYECTOMY
Authors: Sara Hoss, Mahdi Montazeri, Deacon Lee, Olga Katz, Cindy Chow, Raymond Chan, Anthony Ralph-Edwards, Harry Rakowski, Arnon Adler
Journal: Journal of the American College of Cardiology (2021)
N-TERMINAL PRO-BRAIN NATRIURETIC PEPTIDE AND IN-HOSPITAL MORTALITY IN HOSPITALIZED COVID-19 PATIENTS: EXPERIENCE FROM A LARGE HEALTHCARE NETWORK SYSTEM
Authors: Fekadesilassie Moges, Viviana Zlochiver, Ana Cristina Perez Moreno, Jon Wrobel, Khalil Odeh, Ashley Mainville, Michael Peterson, Hlu Vang, Katherine Busniewski, Sara Walczak, Suhail Allaqaband, A. Jamil Tajik, Bijoy Khandheria, M. Fuad Jan
Journal: Journal of the American College of Cardiology (2021)