tbuckley/cabot-search huggingface dataset:
Domestic Abstracts
Journal: JAMA (1988)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Capacitance
Authors: Daniel G. Deschler
Journal: Annals of Internal Medicine (2021)

On Being a DoctorOctober 2021CapacitanceDaniel G. Deschler, MDDaniel G. Deschler, MDMassachusetts Eye and Ear Infirmary and Harvard Medical School, Boston, MassachusettsSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/M21-3162 Audio Reading - “Capacitance” Audio. Michael A. LaCombe, MD, Annals Associate Editor, reads “Capacitance” by Daniel G. Deschler, MD Your browser does not support the audio element. Audio player progress bar Step backward in current audio track Play current audio trackPause current audio track Step forward in current audio track Mute current audio trackUnmute current audio track 00:00/ SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Ca·pac·i·tanceNoun—PHYSICSThe ability of a system to store an electric charge.I am depleted. Everyone is tired. As I look around, we are all still working, trying to regain our previous clip—our sessions; our visits; our RVUs; and, most important, the quality care our patients need and deserve. However, the year has conspired against us and made this effort of giving care so much harder, so much more like work rather than the connected human endeavor at the core of our profession.I see it in some way in everyone throughout the hospital. In the visible upper faces above masked mouths ... Author, Article, and Disclosure InformationAffiliations: Massachusetts Eye and Ear Infirmary and Harvard Medical School, Boston, MassachusettsCorresponding Author: Daniel G. Deschler, MD, Department of Otolaryngology–Head and Neck Surgery, Harvard Medical School, 243 Charles Street, Boston, MA 02114; e-mail, [email protected]Harvard.edu. PreviousarticleNextarticle Advertisement Audio Reading - “Capacitance” Audio. Michael A. LaCombe, MD, Annals Associate Editor, reads “Capacitance” by Daniel G. Deschler, MD Your browser does not support the audio element. Audio player progress bar Step backward in current audio track Play current audio trackPause current audio track Step forward in current audio track Mute current audio trackUnmute current audio track 00:00/ FiguresReferencesRelatedDetails Metrics October 2021Volume 174, Issue 10Page: 1474-1475 ePublished: 19 October 2021 Issue Published: October 2021 Copyright & PermissionsCopyright © 2021 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
A 3D-printed innovative pedal fixator for connecting different pedal-operated tools to improve work ergonomics during advanced diagnostic and therapeutic endoscopic procedures
Authors: Clara Yzet, Jérôme Rivory, Mikael Mochet, Mélia Virely, Peggy Leplat-Bonnevialle, Jérémie Jacques, Mathieu Pioche
Journal: Endoscopy (2022)

Recent techniques in diagnostic and therapeutic endoscopy require the use of different foot-controlled devices. For example, water immersion colonoscopy [1] and underwater endoscopic mucosal resection (EMR) [2] require the parallel use of two foot pedals, one to control the electrosurgical unit and the other to control the peristaltic pump to fill the colon with water. For endoscopic submucosal dissection [3], the problem becomes even more complex with three pedals to be managed in parallel, since the pump that activates the knife injection must be added.
An action plan for preventing coronary heart disease in primary care. Working Group of the Coronary Prevention Group and the British Heart Foundation.
Authors: M Rayner, Geoffrey Rose, Godfrey Fowler, Nicki Spiegal
Journal: BMJ (1991)

An action plan for preventing coronary heart disease in primary care Working Group of the Coronary Prevention Group and the British Heart Foundation Primary health care teams have a great deal to offer in helping people to reduce the high rates of coronary heart disease in the United Kingdom.People can be helped to reduce their risk by giving up smoking, adopting a healthier diet, taking regular exercise, and receiving treatment for high blood pressure.' This action plan aims to help practices target their action against coronary heart disease more effectively and efficiently.It provides practices with a flexible system of deciding which patients should receive a particular level of care that takes into account the resources they have available and wish to devote to preventing coronary heart disease.It proposes that practices should allocate patients into two groups: a special care group to receive special attention because of their relatively high level of risk and a general advice group to receive less attention because of their lower level of risk.2][3] The plan can also be used by practices undertaking any level of testing.
Efficient recovery of potent tumour-infiltrating lymphocytes through quantitative immunomagnetic cell sorting
Authors: Zongjie Wang, Sharif Ahmed, Mahmoud Labib, Hansen Wang, Xiyue Hu, Jiarun Wei, Yuxi Yao, Jason Moffat, Edward H. Sargent, Shana O. Kelley
Journal: Nature Biomedical Engineering (2022)
Validation of the parent-proxy reported Food Allergy-related Quality of Life Questionnaire (FAQLQ-PF-10) short form in a large, multisite longitudinal cohort of food allergic child-parent dyads
Authors: Christopher Warren, Linda Herbert, Lisa Lombard, Lucy Bilaver, Khalid Ibrahim, Andrea Pappalardo, Pamela Newmark, Hemant Sharma, Mary Tobin, Amal Assa'ad, Mahboobeh Mahdavinia, Susan Fox, Amaziah Coleman, Izeris Ortiz Rodriguez, Sai Nimmagada, Andrea Pappalardo, Jialing Jiang, Jacqueline Pongracic, Eileen Vincent, Haley Hultquist, Ososese Enaholo, Davida Kay, Stephanie Shigo, Neil Thivalapill, Ruchi Gupta, Audrey Dunn Galvin
Journal: Journal of Allergy and Clinical Immunology (2022)
Injectable Extracellular Matrix Microparticles Promote Heart Regeneration in Mice with Post‐ischemic Heart Injury
Authors: Xinming Wang, Ali Ansari, Valinteshley Pierre, Kathleen Young, Chandrasekhar R. Kothapalli, Horst A. von Recum, Samuel E. Senyo
Journal: Advanced Healthcare Materials (2022)

Abstract Ischemic heart injury causes permanent cardiomyocyte loss and fibrosis impairing cardiac function. Tissue derived biomaterials have shown promise as an injectable treatment for the post‐ischemic heart. Specifically, decellularized extracellular matrix (dECM) is a protein rich suspension that forms a therapeutic hydrogel once injected and improves the heart post‐injury response in rodents and pig models. Current dECM‐derived biomaterials are delivered to the heart as a liquid dECM hydrogel precursor or colloidal suspension, which gels over several minutes. To increase the functionality of the dECM therapy, an injectable solid dECM microparticle formulation derived from heart tissue to control sizing and extend stability in aqueous conditions is developed. When delivered into the infarcted mouse heart, these dECM microparticles protect cardiac function promote vessel density and reduce left ventricular remodeling by sustained delivery of biomolecules. Longer retention, higher stiffness, and slower protein release of dECM microparticles are noted compared to liquid dECM hydrogel precursor. In addition, the dECM microparticle can be developed as a platform for macromolecule delivery. Together, the results suggest that dECM microparticles can be developed as a modular therapy for heart injury.
Digging Deeper for the Differential Diagnosis of Negative P Waves in Lead I
Authors: Yun-Tao Zhao, Lei Wang
Journal: JAMA Internal Medicine (2022)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Internal Medicine HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Internal Medicine journal
JAMA 75 YEARS AGO
Journal: JAMA (1978)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Panoramic Insights into Microevolution and Macroevolution of a <i>Prevotella Copri</i>-Containing Lineage in Primate Guts
Authors: Hao Li, Jan P. Meier-Kolthoff, Canxin Hu, Zhongjie Wang, Jun Zhu, Wei Zheng, Yun Tian, Feng Guo
Journal: Genomics Proteomics & Bioinformatics (2022)

Abstract Prevotella copri and its related taxa are widely detected in mammalian gut microbiomes and have been linked with an enterotype in humans. However, their microevolution and macroevolution among hosts are poorly characterized. In this study, extensively collected marker genes and genomes were analyzed to trace their evolutionary history, host specificity, and biogeographic distribution. Investigations based on marker genes and genomes suggest that a P. copri-containing lineage (PCL) harbors diverse species in higher primates. Firstly, P. copri in the human gut consisted of multiple groups exhibiting high genomic divergence and conspicuous but non-strict biogeographic patterns. Most African strains with high genomic divergence from other strains were phylogenetically located at the root of the species, indicating the co-evolutionary history of P. copri and Homo sapiens. Secondly, although long-term co-evolution between PCL and higher primates was revealed, sporadic signals of co-speciation and extensive host jumping of PCL members were suggested among higher primates. Metagenomic and phylogenetic analyses indicated that P. copri and other PCL species found in domesticated mammals had been recently transmitted from humans. Thirdly, strong evidence was found on the extensively horizontal transfer of genes (e.g., genes encoding carbohydrate-active enzymes) among sympatric P. copri groups and PCL species in the same primate host. Our study provides panoramic insights into the combined effects of vertical and horizontal transmission, as well as potential niche adaptation, on the microevolutionary and macroevolutionary history for an enterotype-representative lineage.
Alternative Splicing in CKD
Authors: Megan Stevens, Sebastian Oltean
Journal: Journal of the American Society of Nephrology (2016)

Alternative splicing (AS) has emerged in the postgenomic era as one of the main drivers of proteome diversity, with ≥94% of multiexon genes alternatively spliced in humans. AS is therefore one of the main control mechanisms for cell phenotype, and is a process deregulated in disease. Numerous reports describe pathogenic mutations in splice factors, splice sites, or regulatory sequences. Additionally, compared with the physiologic state, disease often associates with an abnormal proportion of splice isoforms (or novel isoforms), without an apparent driver mutation. It is therefore essential to study how AS is regulated in physiology, how it contributes to pathogenesis, and whether we can manipulate faulty splicing for therapeutic advantage. Although the disease most commonly linked to deregulation of AS in several genes is cancer, many reports detail pathogenic splice variants in diseases ranging from neuromuscular disorders to diabetes or cardiomyopathies. A plethora of splice variants have been implicated in CKDs as well. In this review, we describe examples of these CKD-associated splice variants and ideas on how to manipulate them for therapeutic benefit.
"Atmospheric Pollen Count And Its Airborne Calendar In Northeastern Mexico"
Authors: Cindy Elizabeth de Lira-Quezada, Sandra González Díaz, Rosalaura Villarreal-González, Carlos Macouzet-Sanchez, Laura Paola Escamilla-Luna, Miriam Bárcenas-Aguilar, Mariano García-Campa
Journal: Journal of Allergy and Clinical Immunology (2022)
For serous otitis media, laser myringotomy?
Journal: JAMA (1979)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
ESCMID guidelines on testing for SARS-CoV-2 in asymptomatic individuals to prevent transmission in the health care setting
Authors: Elena Carrara, David S.Y. Ong, Khetam Hussein, Siran Keske, Anders F. Johansson, Elisabeth Presterl, Constantinos Tsioutis, Sarah Tschudin-Sutter, Evelina Tacconelli
Journal: Clinical Microbiology and Infection (2022)
New Data on Retinopathy in Youth-Onset Type 2 Diabetes
Authors: Anita Slomski
Journal: JAMA (2022)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Neutralizing antibody activity against the B.1.617.2 (delta) variant 8 months after two-dose vaccination with BNT162b2 in health care workers
Authors: Louise Benning, Christian Morath, Marie Bartenschlager, Marvin Reineke, Maximilian Töllner, Christian Nusshag, Florian Kälble, Paula Reichel, Matthias Schaier, Katrin Klein, Paul Schnitzler, Martin Zeier, Caner Süsal, Ralf Bartenschlager, Claudius Speer
Journal: Clinical Microbiology and Infection (2022)
ASTHMATIC DEATHS IN CHILDREN
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
IL-17 Synthesis in Patients with Psoriasis Varies with Obesity and May be Regulated by Histamine Receptors
Authors: Levon Gevorkyan, Nikolai Potekaev, O. Zhukova, A. Savastenko, S. Artemyeva, Roman Khanferyan, Lawrence DuBuske
Journal: Journal of Allergy and Clinical Immunology (2022)
Public health: invisible in plain sight
Authors: Ishani Kar-Purkayastha
Journal: BMJ (2022)

My daughters were seven and four when the first wave of the pandemic hit in March 2020.In those early weeks, we didn't see much of each other.Even though we were in the same physical space, I was caught up in work.They understood.They coped remarkably.And in the evenings, hazy with exhaustion and uncertainty, they were keen to join with everyone else, clapping and cheering, distanced but together, in giving their thanks for the NHS and other key workers.
Inhibition of P38 mitogen-activated protein kinase protects the heart against cardiac remodeling in mice with heart failure due to myocardial infarction
Authors: Yun-He Liu, Dahai Wang, Nour-Eddine Rhaleb, Xiao-Ping Yang, Jiang Xu, Ai-Li Yu, Amy E. Rudolph, Oscar A. Carretero
Journal: Journal of the American College of Cardiology (2003)
Extramedullary erythropoiesis in human liver grafts*1
Authors: H JURGENSCHLITT
Journal: Hepatology (1995)

Extramedullary erythropoiesis in the adult is very rare and is generally confined to situations of severe bone marrow irritation or replacement. In this study, we describe the occurrence of intrahepatic erythropoiesis in patients who have received a liver allograft and who have no evidence of bone marrow dysfunction. By routinely performed transplant aspiration cytology (TAC), marked intrahepatic erythropoiesis could be detected in 39 of 312 patients (12.5%) with liver allograft. In 19 patients, including 5 of 8 (63%) after combined liver and kidney transplantation, intrahepatic erythropoiesis occurred within the first 3 weeks after surgery. Twenty patients showed intrahepatic erythropoiesis between 3 weeks and 4 months after transplantation. Erythropoiesis was usually transient, lasting between 1 and 3 weeks. Cytologically, mature as well as immature erythroblasts of GlyA+ CD36+ CD45− phenotype could be detected in the grafts, whereas they were absent in blood; histologically, the cells could be localized to the sinusoids of the liver. There was no clear correlation of preoperative or postoperative hemoglobin levels, graft function, kidney function, and immunosuppressive medication with the presence or absence of erythropoiesis. Moreover, serum levels of erythropoietin (EPO) and stem cell factor (SCF) in patients with and without intrahepatic erythropoiesis in the early postoperative phase did not show significant differences. These findings show that intrahepatic erythropoiesis can occur transiently in human liver allografts and suggest that systemic stimuli as well as local factors may contribute to it.
A Survivor
Authors: Irwin M. Siegel
Journal: JAMA (1982)

"The procedure is all over, Mrs Greenberg. You're back in your own room now." "But... where are the others, where have they gone?" "What others, Mrs Greenberg? There are no others, only you. The operation is over, your hip is fixed, and you're back in your own bed. We'll get you up soon and in a day or two you'll be walking again." "The rest of the barracks, where have they gone?" "What barracks, Mrs Greenberg? This is no barracks. This is a hospital." "They've taken them all to the chimneys! I am the only one left now! Why didn't they take me too? What did I do to be punished like this?" "You're confused, Mrs Greenberg. Don't you remember where you are? Here, look at me. I'm your doctor. Don't you remember me?" "They're all burning by now. Mina's thin legs are burning, Rachel's old hands are burning, Sarah's
Triple-synergistic MOF-nanozyme for efficient antibacterial treatment
Authors: Muxue Wang, Xi Zhou, Yunhong Li, Yuqing Dong, Jiashen Meng, Shuai Zhang, Linbo Xia, Zhaozhi He, Lei Ren, Zhiwei Chen, Xingcai Zhang
Journal: Bioactive Materials (2022)

The abuse of antibiotics makes bacterial infection an increasingly serious global health threat. Reactive oxygen species (ROS) are the ideal alternative antibacterial approach for quick and effective sterilization. Although various antibacterial strategies based on ROS have been developed, many of them are still limited by insufficient antibacterial efficiency. Here, we have developed an acid-enhanced dual-modal antibacterial strategy based on zeolitic imidazolate frameworks-8 (ZIF8) -derived nanozyme. ZIF8, which can release Zn