Residual Shunt After Patent Foramen Ovale Closure and Long-Term Stroke Recurrence
Authors: Alexia Karagianni, Peter Eriksson, Mikael Dellborg
Journal: Annals of Internal Medicine (2020)

Letters1 December 2020Residual Shunt After Patent Foramen Ovale Closure and Long-Term Stroke RecurrenceAlexia Karagianni, MD, Peter Eriksson, MD, PhD, and Mikael Dellborg, MD, PhDAlexia Karagianni, MDSahlgrenska Academy University of Gothenburg, Gothenburg, Sweden (A.K., P.E., M.D.)Search for more papers by this author, Peter Eriksson, MD, PhDSahlgrenska Academy University of Gothenburg, Gothenburg, Sweden (A.K., P.E., M.D.)Search for more papers by this author, and Mikael Dellborg, MD, PhDSahlgrenska Academy University of Gothenburg, Gothenburg, Sweden (A.K., P.E., M.D.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/L20-1273 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:We read Deng and colleagues' article (1) with interest. We recently reported on 282 patients with stroke/TIA and cryptogenic stroke who had PFO closure by catheter intervention between 2006 and 2014 (2). After 8.4 years of follow-up, the rate of recurrent stroke was 3.2 events per 100 patient-years among patients with residual shunt versus 0.8 events per 100 patient-years for patients without shunt, occurring a median of 4 years after PFO closure. These findings are similar to those in Deng and colleagues' article, which reported 2.32 and 0.75 events per 100 patient-years in the shunt and no-shunt ...References1. Deng W, Yin S, McMullin D, et al. Residual shunt after patent foramen ovale closure and long-term stroke recurrence. A prospective cohort study. Ann Intern Med. 2020;172:717-25. doi:10.7326/M19-3583 LinkGoogle Scholar2. Karagianni A, Mandalenakis Z, Dellborg M, et al. Recurrent cerebrovascular events in patients after percutaneous closure of patent foramen ovale. J Stroke Cerebrovasc Dis. 2020;29:104860. [PMID: 32430239] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Sahlgrenska Academy University of Gothenburg, Gothenburg, Sweden (A.K., P.E., M.D.)Disclosures: Authors have disclosed no conflicts of interest. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L20-1273. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoResidual Shunt After Patent Foramen Ovale Closure and Long-Term Stroke Recurrence Wenjun Deng , Shanye Yin , David McMullin , Ignacio Inglessis-Azuaje , Sammy Elmariah , Judy Hung , Eng H. Lo , Igor F. Palacios , Ferdinando S. Buonanno , and MingMing Ning Residual Shunt After Patent Foramen Ovale Closure and Long-Term Stroke Recurrence Preetham Kumar , Mohammad K. Mojadidi , and Jonathan M. Tobis Residual Shunt After Patent Foramen Ovale Closure and Long-Term Stroke Recurrence Gaurav Aggarwal , Saurabh Aggarwal , and Marc Cohen Metrics 1 December 2020Volume 173, Issue 11Page: 945-946KeywordsCathetersConflicts of interestDisclosureMedical risk factorsReasoningStrokeTransient ischemic attacks ePublished: 1 December 2020 Issue Published: 1 December 2020 Copyright & PermissionsCopyright © 2020 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...