Drug Effects on Driving Performance
Authors: John M. Weiler
Journal: Annals of Internal Medicine (2000)

Letters17 October 2000Drug Effects on Driving PerformanceJohn M. Weiler, MD, George Woodworth, PhD, and Ginger Watson, PhDJohn M. Weiler, MDUniversity of Iowa; Iowa City, IA 52242 (Weiler, Woodworth, Watson)Search for more papers by this author, George Woodworth, PhDUniversity of Iowa; Iowa City, IA 52242 (Weiler, Woodworth, Watson)Search for more papers by this author, and Ginger Watson, PhDUniversity of Iowa; Iowa City, IA 52242 (Weiler, Woodworth, Watson)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-133-8-200010170-00024 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:We agree with de Waard and Brookhuis that delay (phase) is a meaningful, reliable, and sensitive measure related to coherence; in our study, phase produced results similar to those produced by coherence. Their reference (1) should have been cited. Our figure, unlike theirs, demonstrates different drivers with good, median, and poor coherence; we did not show data on the lead vehicle.Accident data studies are difficult to interpret. Fatal events are rare, and often we cannot ascertain the confounding role of medications. Other studies referenced by Lee and colleagues are not driving studies and used insensitive end points.... References1. Brookhuis KA, de Waard D, Mulder LJ. Measuring driving performance by car following in traffic. Ergonomics. 1994;37:427-34. CrossrefGoogle Scholar2. Better Homes and Gardens. May 2000:57. Google Scholar3. Moskowitz H. Validity of driving simulator studies for predicting drug effects in real driving situations.. In: Israelstam S, Lambert S, eds. Alcohol, Drugs and Traffic Safety: Proceedings of the 6th International Conference on Alcohol, Drugs, and Traffic Safety. Toronto: Addiction Research Foundation of Ontario; 1974:295-303. Google Scholar4. Friedel B, Joo S, Reker K, Kading W, Klostermann P, Saternus KS, et al. Test drivers in the Daimler-Benz driving simulator with drivers under diphenhydramine. Washington, DC: National Highway Traffic Safety Administration; 1991. US-DOT-HS-807-668; NTIS No. PB91-230896. Google Scholar5. Hindmarch I, Shamsi Z. Antihistamines: models to assess sedative properties, assessment of sedation, safety and other side-effects. Clin Exp Allergy. 1999;29:133-42. CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: University of Iowa; Iowa City, IA 52242 (Weiler, Woodworth, Watson) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoEffects of Fexofenadine, Diphenhydramine, and Alcohol on Driving Performance John M. Weiler , John R. Bloomfield , George G. Woodworth , Angela R. Grant , Teresa A. Layton , Timothy L. Brown , David R. McKenzie , Thomas W. Baker , and Ginger S. Watson Drug Effects on Driving Performance Dick de Waard and Karel A. Brookhuis Drug Effects on Driving Performance Thomas H. Lee , Jessica Dudley , and Harold J. Demonaco Drug Effects on Driving Performance James T. Angello and Howard M. Druce Metrics Cited byMisuse and Dependence on Non-Prescription Codeine Analgesics or Sedative H1 Antihistamines by Adults: A Cross-Sectional Investigation in FranceCognitive Cars: A New Frontier for ADAS ResearchRhinologic pharmacotherapy in rhinoplastyCurrent Awareness 17 October 2000Volume 133, Issue 8Page: 657-658KeywordsAlcoholsAllergic rhinitisAntihistaminesDrug regulationDrugsFatigueIngestionSedativesSleepStandard error ePublished: 17 October 2000 Issue Published: 17 October 2000 Copyright & PermissionsCopyright © 2000 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...