IMMUNOLOGIC STUDIES IN RHEUMATIC FEVER
Authors: M. S. S.
Journal: Annals of Internal Medicine (1949)

Editorial1 August 1949IMMUNOLOGIC STUDIES IN RHEUMATIC FEVERM. S. S.M. S. S.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-31-2-354 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptDespite intensive investigation the etiology of rheumatic fever remains obscure. Important evidence has been accumulated, however, concerning a variety of contributory factors. Thus, it is generally agreed that the disease occurs more commonly under cool, damp climatic conditions than in warm, dry climates.1Epidemiologic data also permit the generalization that a poor economic status with its corollaries of overcrowding and undernutrition provides a more fertile soil for the development of rheumatic fever than the antithetical situation.1In addition to such external factors, careful students of the subject now firmly believe that the susceptibility to rheumatic fever is inherited as a...1 PAUL JR: Epidemiology of rheumatic fever and some of its public health aspects. For the American Heart Association, Metropolitan Life Insurance Co., ed. 2, 1943. Google Scholar2 WILSON MG: Heredity and rheumatic disease, Am. Jr. Med., 1947, ii, 190. CrossrefGoogle Scholar3 ANGERINEROTHBARDCECIL DMSRL: Cultural studies on rheumatoid arthritis and rheumatic fever, Jr. Am. Med. Assoc., 1940, cxv, 2112. Google Scholar4 PAUL JR: Epidemiology of rheumatic fever, Am. Jr. Med., 1947, ii, 66. CrossrefGoogle Scholar5 VAN RAVENSWAAY AC: The geographic distribution of hemolytic streptococci. Relationships to the incidence of rheumatic fever, Jr. Am. Med Assoc., 1944, cxxvi, 486. CrossrefGoogle Scholar6 JONESMOTE TDJR: The clinical importance of infection of the respiratory tract in rheumatic fever, Jr. Am. Med. Assoc., 1939, cxiii, 898. CrossrefGoogle Scholar7 HARRIS TN: Studies on the relation of the hemolytic streptococcus to rheumatic fever. I. Review of serologic literature, Am. Jr. Dis. Child., 1948, lxxvi, 411. CrossrefGoogle Scholar8 GOLDIEGRIFFITHS WGJ: Aetiological relation of the Streptococcus hemolyticus to the "rheumatic" disease, Brit. Med. Jr., 1936, ii, 755. CrossrefGoogle Scholar9 MEYER K: The biological significance of hyaluronic acid and hyaluronidase, Physiol. Rev., 1947, xxvii, 335. CrossrefGoogle Scholar10 HARRISHARRISNAGLE TNSRL: Studies in the relation of the hemolytic streptococcus to rheumatic fever. VI. Comparison of streptococcal anti-hyaluronidase with antibodies to other streptococcal antigens in the serum of patients with rheumatic fever and acute streptococcal infection. Mucin clot prevention test, Pediatrics, 1949, iii, 482. Google Scholar11 FRIOUWENNER JJHA: On the occurrence in human serum of an inhibitory substance to hyaluronidase produced by a strain of hemolytic streptococcus, Jr. Infect. Dis., 1947, lxxx, 185. CrossrefGoogle Scholar12 SWIFT HF: Rheumatic fever. Hektoen Lecture, Billings Foundation, Jr. Am. Med. Assoc., 1929, xcii, 2071. CrossrefGoogle Scholar13 COBURN AF: Rheumatic fever problem. I. Present status. II. Approaches awaiting development, Am. Jr. Dis. Child., 1945, lxx, 339 and 348. CrossrefGoogle Scholar14 WEDUMWEDUM AGBG: Serum precipitation reaction in rheumatic fever and in other conditions, Proc. Soc. Exper. Biol. and Med., 1946, lxi, 432. CrossrefGoogle Scholar15 CAVELTICAVELTI PAES: Studies on the pathogenesis of glomerulo-nephritis. I. Production of auto-antibodies to kidney in experimental animals, Arch. Path., 1945, xxxix, 148. Google Scholar16 CAVELTICAVELTI PAES: Studies on the pathogenesis of glomerulo-nephritis. II. Production of glomerulonephritis in rats by means of auto-antibodies to kidneys, Arch. Path., 1945, xl, 158. Google Scholar17 CAVELTICAVELTI PAES: Studies on the pathogenesis of glomerulonephritis. III. Clinical and pathological aspects of the experimental glomerulonephritis produced in rats by means of auto-antibodies to kidney, Arch. Path., 1945, xl, 103. Google Scholar18 CAVELTI PA: Studies on the pathogenesis of rheumatic fever. I. Production of auto-antibodies to heart, skeletal muscle, and connective tissue in experimental animals, Arch. Path., 1947, xliv, 1. II. Cardiac lesions produced in rats by means of auto-antibodies to heart and connective tissue, Arch. Path., 1947, xliv, 13. Google Scholar19 CAVELTI PA: Auto-antibodies in rheumatic fever, Proc. Soc. Exper. Biol. and Med., 1945, lx, 379. CrossrefGoogle Scholar20 KERR WJ: Pathogenesis of rheumatic fever, Ann. Int. Med., 1948, xxix, 587. Google Scholar21 RICH AR: Hypersensitivity in disease with especial reference to periarteritis nodosa, rheumatic fever, disseminated lupus erythematosus and rheumatoid arthritis, Harvey Lect., 1946-47, xlii, 106. Google Scholar22 WOODS AC: Allergy and immunity in ophthalmology, The Johns Hopkins Press, Baltimore, 1933. Google Scholar23 MORGAN IM: Allergic encephalomyelitis in monkeys in response to injection of normal monkey nervous tissue, Jr. Exper. Med., 1947, lxxxv, 131. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 August 1949Volume 31, Issue 2Page: 354-358KeywordsDeoxyadenosine monophosphateEpidemiologyEtiologyRheumatic fever ePublished: 1 December 2008 Issue Published: 1 August 1949 PDF downloadLoading ...