tbuckley/cabot-search huggingface dataset:
SAT0051 Cox-2 specific inhibition with mk-0663 120 mg q. d. over 4 weeks did not increase faecal blood loss: a controlled study with placebo and ibuprofen 800 mg t.i.d
Authors: RH Hunt, P Callegari, B Bowen, C James, J Marshall, E Mortensen, A Cagliola, C Yu, H Quan, T Simon
Journal: Annals of the Rheumatic Diseases (2001)

<h3>Background</h3> Treatment with existing NSAIDs is associated with increased gastrointestinal microbleeding. We conducted a double-blind, single centre study in 62 healthy volunteers (age 19–33 years) to test the hypothesis that faecal blood loss with MK-0663 (a new highly selective COX-2 inhibitor with a selectivity ratio of &gt;100 in human whole blood assay) would be equivalent to placebo and superior to ibuprofen. <h3>Objectives</h3> To compare faecal blood loss in volunteers taking MK-0663, ibuprofen, or placebo. <h3>Methods</h3> Subjects were injected with <sup>51</sup>Cr labelled red blood cells and daily faecal blood loss in collected stool was measured by a large sample counter. Subjects with normal faecal blood loss during a 1-week placebo baseline period were randomised to MK-0663 120 mg q.d., ibuprofen 800 mg t.i.d. or placebo treatment for 28 days. The effects of MK-0663 and placebo were compared by a predefined similarity bound for determination of equivalence. <h3>Results</h3> The mean daily faecal blood loss (mL/day) over time is shown in the table below. MK-0663 (120 mg) was equivalent to placebo and caused less blood loss than ibuprofen. All treatments were generally well tolerated. <h3>Conclusion</h3> In this study, the highly selective COX-2 inhibitor, MK-0663, at a dose twice that maximally effective in osteoarthritis, was equivalent to placebo, whereas a therapeutic dose of ibuprofen significantly increased faecal blood loss.
The Anti-Tumor Activity of Igm-8444, an Agonistic Death Receptor 5 (DR5) IgM Antibody, Is Sensitized in Combination with Chemotherapy and Bcl-2 Inhibitors in NHL and AML
Authors: Beatrice T. Wang, Thomas J. Matthew, Ling Wang, Tasnim Kothambawala, Susan E. Calhoun, Eric W. Humke, Angus M. Sinclair, Bruce A. Keyt
Journal: Blood (2020)
Application of Novel T Cell Immunotherapeutics to Drive Antigen-Specific Activation, Expansion, and Differentiation of CD19 Chimeric Antigen Receptor T Cells (CAR T-cells)
Authors: Moriah Rabin, Mengyan Li, Scott Garforth, Jacqueline Marino, Jian Hua Zheng, Kaitlyn E. O'Connor, Steven C. Almo, Harris Goldstein
Journal: Blood (2020)
Therapeutic Activity of Combining BCL-2 and HMG-CoA Reductase Inhibition in Systemic Light-Chain Amyloidosis
Authors: Ping Zhou, Hashim Mann, Xun Ma, Teresa Fogaren, Yifei Zhang, Denis Toskic, Chakra P Chaulagain, Cindy Varga, Raymond L. Comenzo, Amandeep Godara
Journal: Blood (2020)
THU0055 Role of antibodies to 5’nucleotidase in rheumatoid arthritis, systemic lupus erythematosus, systemic sclerosis, ankylosing spondylarthritis and reactive arthritis patients
Authors: AB Zborovsky, BV Zavodovsky, EV Bobicheva, LE Sivordova, NA Fofanova
Journal: Annals of the Rheumatic Diseases (2001)

<h3>Background</h3> <h3>Objectives</h3> Purpose of research was to study presence and role of definition of antibodies to 5'nucleotidase (anti-5NT) in rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), systemic sclerosis (SS), ankylosing spondylarthritis (AS) and reactive arthritis (ReA) patients. <h3>Methods</h3> There were 100 RA, 30 SLE, 20 SS, 30 AS and 20 ReA patients and 30 healthy donors (HD) under our observation. Anti-5NT were determined in serum of a blood with ELISA-test. We used 5'nucleotidase (AN 3.1.3.5) from Crotalus adamenteus venom («Sigma») as antigen. <h3>Results</h3> We revealed, that the anti-5NT level in HD was equal 0,048 ± 0,004, in RA – 0,153 ± 0,012, in SLE – 0,101 ± 0,016, in SS – 0,117 ± 0,017, in AS 0,118 ± 0,015, in ReA – 0,117 ± 0,010 (in all cases p &lt; 0.05). We revealed difference between anti-5NT level in RA and SLE (p &lt; 0,05), that can be used in differential diagnostics of these diseases. Was noted increasing of anti-5NT level in RA with muscles injury (without myositis – 0,150 ± 0,013, with myositis – 0,190 ± 0,002) and kidney manifestations (without nephropathy – 0,149 ± 0,013, with nephropathy – 0,205 ± 0,013). Taking into account that kidney injury in RA associates with perinuclear antineutrophil cytoplasmic antibody, we assume presence of cross reactions between them and anti-5NT. <h3>Conclusion</h3> Thus, we revealed the new group of autoantibodies. The determination of them can improve diagnostics and differential diagnostics and better understanding of rheumatic diseases pathogenesis. <h3>Reference</h3> Mustila A, Korpela M, Mustonen J, et al. Perinuclear antineutrophil cytoplasmic antibody in rheumatoid arthritis: a marker of severe disease with associated nephropathy. Arthritis Rheum. 1997;40(4):710–17
Effect of ABCB1 Multidrug Resistance Protein on Efficacy of Anti-Myeloma Drugs in Carfilzomib-Resistant Myeloma Model
Authors: Konstantin Byrgazov, Marianne Kraus, Andrej Besse, Ana Slipicevic, Fredrik Lehmann, Christoph Driessen, Lenka Besse
Journal: Blood (2020)
Is There a Clinical Benefit to Switch Hydroxyurea (HU) Drug in Sickle Cell Disease (SCD)?
Authors: Frédéric Galactéros, Ersi Voskaridou, Anoosha Habibi, Giovanna Cannas, Laure Joseph, Gylna Loko, Mariane De Montalembert, Narcisse Elenga, Malika Benkerrou
Journal: Blood (2020)
Derived from a Platform of Innovative Therapeutic Molecular Clusters (TMC), Ag5 Is a Highly Potent and Differentiated Molecule That Promises to be Efficacious in Hard-to-Treat Hematological Cancers
Authors: Vanesa Porto González, Carmen Carneiro, Vanesa Santos, Erea Borrajo, Blanca Dominguez, Anxo Vidal, Jose Luis Bello, David Buceta, Arturo Lopez-Quintela, Martin Treder, Fernando Dominguez
Journal: Blood (2020)
The Expression of Paks and Its Clinical Significance in T-Cell Lymphoblastic Lymphoma
Authors: Qingqing Cai, Ning Su, Yu Fang, Xu Chen, Xiaopeng Tian, Shuyun Ma, Xiaoqin Chen, Zhongjun Xia, Tongyu Lin, Huiqiang Huang, Zhiming Li, Xueyi Pan, Yi Xia, Panpan Liu, Xuanye Zhang, Hang Yang, Stephen Yang Liang
Journal: Blood (2020)
CD4+ T-cell reconstitution predicts survival outcomes after acute graft-versus-host-disease: a dual-center validation
Authors: Coco de Koning, Susan Prockop, Ichelle van Roessel, Nancy Kernan, Elizabeth Klein, Jurgen Langenhorst, Celina Szanto, Mirjam Belderbos, Marc Bierings, Farid Boulad, Dorine Bresters, Maria Cancio, Kevin Curran, Wouter Kollen, Richard O’Reilly, Andromachi Scaradavou, Barbara Spitzer, Birgitta Versluijs, Alwin Huitema, Caroline Lindemans, Stefan Nierkens, Jaap Jan Boelens
Journal: Blood (2020)
Super-Resolved <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" altimg="si2.svg"><mml:mi>q</mml:mi></mml:math>-Space deep learning with uncertainty quantification
Authors: Yu Qin, Zhiwen Liu, Chenghao Liu, Yuxing Li, Xiangzhu Zeng, Chuyang Ye
Journal: Medical Image Analysis (2020)
Inhibition of PIM Kinases in Diffuse Large B-Cell Lymphoma Cells Targets MYC-Dependent Transcriptional Program, Increases CD20 Expression and Augments the Efficacy of Anti-CD20 Antibodies
Authors: Maciej Szydlowski, Filip Garbicz, Ewa Jabłońska, Patryk Górniak, Beata Pyrzynska, Kamil Bojarczuk, Dorota Komar, Monika Prochorec-Sobieszek, Anna Szumera-Ciećkiewicz, Grzegorz Rymkiewicz, Magdalena Cybulska, Małgorzata Statkiewicz, Marta Gajewska, MIchał Mikula, Aniela Golas, Joanna Domagała, Magdalena Winiarska, Agnieszka Graczyk-Jarzynka, Emilia Bialopiotrowicz, Anna Polak, Joanna Barankiewicz, Bartosz Pula, Michael R Green, Dominika Nowis, Jakub Golab, Andrea Massimiliano Tomirotti, Krzysztof Brzózka, Mariana Pacheco-Blanco, Kristyna Kupcova, Ondrej Havranek, Bjoern Chapuy, Przemyslaw Juszczynski
Journal: Blood (2020)
Identification of a Novel Role for PD-1 Signaling in Promotion Tumor Proliferation in B-Cell Lymphoma
Authors: Sutapa Sinha, Wei Ding, Tammy Price-Troska, Reona Sakemura, Shulan Tian, Charla R. Secreto, Xiaosheng Wu, Timothy G. Call, Rong He, Sameer A. Parikh, Yucai Wang, Jose F. Leis, Huihuang Yan, Karen Rech, Amber B. Koehler, Daniel L. Van Dyke, Minetta C. Liu, Susan L. Slager, Esteban Braggio, Stephen M. Ansell, Saad S. Kenderian, Neil E. Kay
Journal: Blood (2020)
Estimates and Timing of Therapy Initiation during the First Decade for Patients with Follicular Lymphoma Who Were Observed at Diagnosis
Authors: Arushi Khurana, Raphael Mwangi, Stephen M. Ansell, Thomas M. Habermann, James R. Cerhan, Christopher Strouse, Brian K. Link, Yucai Wang, Rebecca L. King, William R. Macon, Jose C Villasboas, Thomas E. Witzig, Matthew J. Maurer, Grzegorz S. Nowakowski
Journal: Blood (2020)
Tumor Microenvironment in Patients with Relapsed/Refractory Classical Hodgkin Lymphoma before and after Anti-PD-1 Therapy
Authors: Artem A. Gusak, Kirill V. Lepik, Natalia B. Mikhailova, Elena Kondakova, Yuri R. Zalaylov, Marina O. Popova, Tatiana I. Ionova, Aleksandr D. Kulagin, Boris V. Afanasyev, Vadim Baykov
Journal: Blood (2020)
Long-Term Sustained Minimal Residual Disease (MRD) Negativity in Patients with Multiple Myeloma Treated with Continuous Lenalidomide Maintenance Therapy: A Clinical and Correlative Phase 2 Study
Authors: Benjamin Diamond, Neha Korde, Alexander M. Lesokhin, Eric L Smith, Urvi A Shah, Sham Mailankody, Malin Hultcrantz, Hani Hassoun, Sydney X. Lu, Carlyn Tan, Donna Massey, Meghan Salcedo, Victoria Diab, Kelly Werner, Jenna Rispoli, Allison Sams, Dennis Verducci, Katie Jones, Julia Schlossman, Aisara Chansakul, Angela Harrison, Amanda Kathryn Ciardiello, Elizabet Tavitian, Tala Shekarkhand, Casey Piacentini, Even H Rustad, Venkata D Yellapantula, Francesco Maura, Tim J Peterson, Andriy Derkach, Sean Devlin, Heather J Landau, Michael Scordo, David J. Chung, Gunjan L. Shah, Oscar B Lahoud, Katie Thoren, Kazunori Murata, Lakshmi Ramanathan, Maria E. Arcila, Caleb Ho, Mikhail Roshal, Ahmet Dogan, Sergio A. Giralt, Ola Landgren
Journal: Blood (2020)
THU0105 The effects of interleukin-17 on production of vascular endothelial growth factor in cultured rheumatoid arthritis synoviocytes
Authors: K Sung, K Ihm Soo, K Ha Yeon, K Yu Sun
Journal: Annals of the Rheumatic Diseases (2001)

<h3>Background</h3> <h3>Objectives</h3> To investigate the effects of interleukin-17 (IL-17) on the production of vascular endothelial growth factor (VEGF) from cultured rheumatoid arthritis synoviocytes. <h3>Methods</h3> Fibroblast-like synovial cells (FLS) were prepared from the synovial tissues of rheumatoid arthritis patients and cultured in the presence of IL-17, transforming growth factor-b (TGF-b), tumour necrosis factor-α (TNF-α) and interleukin-1b (IL-1b). VEGF levels were determined in the culture supernatants by sandwitch ELISA. <h3>Results</h3> Stimulation of FLS by serial concentration of IL-17, TGF-b, TNF-α, IL-1b increased the production of VEGF by 2.1–2.7, 2.2–3.0, 2.0–2.9, 2.3–3.1 fold over the constitutive levels of unstimulated FLS. Stimulation of FLS by IL-17 with TGF-b, TNF-α or IL-1b also increased the production of VEGF according to culture periods by 1.6–1.8, 1.1–1.9, 1.5–1.7 fold over the levels stimulated with TFG-b or TNF-α or IL-1b, respectively. This results indicated that IL-17 increased the effect of TGF-b, TNF-α, IL-1b on FLS, leading synergistic enhancement of VEGF production. <h3>Conclusion</h3> IL-17 may be involved in the neovascularization in rheumatoid synovitis by enhancing the production of VEGF.
Peripheral Venous Access for Collection of Immune Effector Cells and Hematopoietic Stem Cells Is Feasible and Safe in Older Children and Young Adult Patients
Authors: Joel Livingston, Maria Di-Mola, Jane Lowry, Nigel Ruse, Christoph Licht, Muhammad Ali, Tal Schechter-Finkelstein, KY Chiang, Joerg Krueger
Journal: Blood (2020)
The Prevalence and Impact of Arrhythmias in Hospitalized Patients with Sickle Cell Disorders: A Large Database Analysis
Authors: Ankita Kapoor, Samarthkumar Thakkar, Lucas Battel, Harsh P. Patel, Nikhil Agrawal, Shipra Gandhi, Pritika Manaktala, Arjun Khunger, Taha Saeed, Virmitra G. Desai, Peter A. Kouides
Journal: Blood (2020)
Abstract 429: Tnf Receptor-1 Dictates Life/death Decisions of Auto-reactive T-lymphocytes During Heart Failure
Authors: SARITA NEHRA, Rachel Rosenzweig, Oscar Bermeo-Blanco, ERIC X BECK, Noah L Weisleder, Richard J Gumina, Shyam S Bansal
Journal: Circulation Research (2020)

Ischemic heart failure (HF) results in the activation of self-reactive CD4+ T-lymphocytes against unknown cardiac antigens. The mechanisms that mediate the survival of self-reactive T-cells during ischemic HF are not known. TNF mediated NF-kB signaling regulates cellular apoptotic pathways and T cells express high levels of TNF receptor-1 (TNFR1) during chronic heart failure. Thus, we hypothesized that TNFR1 regulates pro-apoptotic signaling through NF-kB and is critical for the clearance of self-reactive T-cells during HF. To test this, male WT or TNFR1 -/- mice underwent coronary artery ligation to induce HF (10 wks post-ligation), followed by isolation and adoptive-transfer (AT) of splenic CD4+ T-cells (9X10 6 cells/mouse) into the tail-veins of naïve CD45.1 mice. Flow cytometric analysis showed ~7-fold higher levels of HF-activated TNFR1 -/- T cells in recipient mice when compared with WT T-cells at 2d post-AT, and were not different between the 2-groups at 1 wk. Interestingly, TNFR1 -/- T cells were significantly higher again at 2 wks (as compared to WT T-cells) and the levels were sustained for up to 14 wks post-AT. In contrast, donor WT T-cells were slowly cleared from the recipient mice. In addition, as compared to WT T-cells, ~11-fold higher levels of adoptively transferred TNFR1 -/- T cells were observed in the spleens of recipient mice at 14 wks suggesting that TNFR1 -/- T cells had higher propensity to seed into the lymphoid tissues. This data also suggests that TNFR1 -/- T cells either have enhanced pro-survival pathways or were less prone to activation-induced cell death. In-vitro T-cell proliferation assays using anti-CD3/CD28 antibodies showed enhanced proliferation and expression of anti-apoptotic Bcl-xL upon treatment with a TNFR1 neutralization antibody corroborating in-vivo results. Intriguingly, as opposed to WT T-cells, adoptive transfer of HF-activated TNFR1 -/- T-cells induced significant cardiac dysfunction and the ejection fraction (EF) of naïve recipient mice was significantly decreased from 63±6% to 45±6% at 14 weeks post-AT. Our data show that TNFR1 signaling regulates pro-vs anti-apoptotic pathways in a context-dependent manner and potentiate pathological phenotype of HF activated T-cells by enhancing their life-span.
Potential Utilization of Lymphoscintigraphy in Patients With Klippel-Trenaunay Syndrome
Authors: Zhe Wen, Guansheng Tong, Yong Liu
Journal: Clinical Nuclear Medicine (2020)

Purpose Klippel-Trenaunay syndrome (KTS) is a rare disease that was characterized by vascular malformation. Lymphatic malformation was also commonly associated with KTS. However, the application of lymphoscintigraphy in the management of patients with KTS was rarely described. The purpose of this study is to assess whether the findings of lymphoscintigraphy can aid the management of the patients with KTS. Methods A total of 28 patients with known KTS who underwent 99m Tc-dextran lymphoscintigraphy with lower extremity tracer injection were included in this retrospective analysis. The images from lymphoscintigraphy were reviewed for any abnormalities in the body with the attention on the region of left subclavian-jugular venous angle. Results In addition to abnormal activity in the other regions, abnormal activity in the left subclavian-jugular venous angle was visualized in over half of the patients (53.6%, 15/28). Based on the findings of the lymphoscintigraphy, 7 patients with left subclavian-jugular venous angle activity underwent thoracic duct decompression. In 4 patients with postsurgery follow-up, 3 achieved significant, measurable symptomatic relief. Conclusions Lymphoscintigraphy can be used to assess potential candidates for thoracic duct decompression to alleviate the symptoms in patients with KTS.
Deoxyribose oxidation in DNA by reactive nitrogen species: Aldehydic lesions as targets for further oxidation and carbon dioxide modulation of DNA damage chemistry
Authors: Christiane Collins, Xinfeng Zhou, Peter C. Dedon
Journal: Cancer Research (2004)

1881  Deoxyribose oxidation plays a critical role in the genetic toxicology of oxidative stress, including involvement in complex DNA lesions, cross-linking with DNA repair proteins and the formation of endogenous DNA adducts. The latter is illustrated by our discovery that 3′-phosphoglycolaldehyde (PGA), arising from 3′-oxidation of deoxyribose in DNA, reacts to form glyoxal and the mutagenic glyoxal adduct of dG. Given the lack of sensitive methods to quantify deoxyribose oxidation products, we have used PGA as a model to develop a sensitive GC/MS method to identify and quantify deoxyribose oxidation products containing aldehydes and ketones. In previous studies, we demonstrated that gamma-radiation produces 1.5 PGA residues/10e6 nt/Gy in isolated DNA, with PGA representing 1% of deoxyribose oxidation events. Here, we focus on peroxynitrite (ONOO-), a chemical mediator of inflammation that arises from the reaction of superoxide and NO produced by macrophages. Under biological conditions, ONOO- reacts with carbon dioxide to form nitrosoperoxycarbonate (ONOOCOO-), a reaction that shifts the oxidative DNA damage chemistry from predominantly deoxyribose with ONOO- to guanine with ONOOCOO-. To further investigate this issue, we quantified the yield of PGA in isolated DNA in 50 mM phosphate buffer, pH 7.4, with bicarbonate concentrations ranging from 0 to 100 mM and ONOO- concentrations from 0 to 1000 μM. At biologically relevant concentration of 25 mM bicarbonate (∼1 mM carbon dioxide), the production of PGA was below the detection limit of 2 PGA/10e6 nt. The yield of PGA with ONOO- was inversely proportional to the bicarbonate concentration over the range of 0 to 10 mM. This leads us to conclude that ONOOCOO- is either not capable of oxidizing deoxyribose to produce PGA, perhaps due to the low oxidation potential of the carbonate radical anion active intermediate in ONOOCOO-induced oxidations, or that the 3′-oxidation chemistry follows a different path with this oxidant than with ONOO-. Another factor affecting the yield of PGA is the reaction of ONOO- with PGA to form a 3′-phosphoglycolate residue, a less genotoxic DNA oxidation product. To address this question we exposed synthetic PGA and an oligonucleotide containing a 3′-PGA residue to ONOO- in the presence of 1 mM calf thymus DNA in 50 mM phosphate buffer in the presence or absence of 25 mM bicarbonate. While 50% of isolated PGA was oxidized by 1 mM ONOO-, PGA bound to the oligonucleotide was unreactive toward ONOO-. We propose that negative charge repulsion with the sugar-phosphate backbone accounts for the protective effects of the oligonucleotide. These observations suggest that carboin dioxide tension may play a role in defining the spectrum of oxidative DNA lesions in cells and that the reactions by negatively charged oxidants in DNA are limited by charge repulsion.
Role of High Dose Chemotherapy and Autologous Stem Cell Transplant in Relapsed Ewing's Sarcoma — a Systematic Review
Authors: Pavan Tenneti, Umar Zahid, Ahmad Iftikhar, Seongseok Yun, Vikas Kapoor, Azka Latif, Adeela Mushtaq, Raahem Nayab Zafar, Ali McBride, Faiz Anwer
Journal: Blood (2017)
Philadelphia Chromosome‐positive Acute Myeloid Leukemia With e1a3 <i>BCR‐ABL1</i> Fusion Transcript
Authors: Julia W. Sheets, Patrick Eulitt, Rong He, Horatiu Olteanu, Catherine C. Coombs, Matthew C. Foster, Nathan D. Montgomery, Joshua F. Zeidner
Journal: HemaSphere (2020)

Supplemental Digital Content is available in the text
The cancer hypothesis of pulmonary arterial hypertension: are polyamines the new Warburg?
Authors: Christopher J. Rhodes
Journal: European Respiratory Journal (2020)

Since the identification of elevated anaerobic glycolysis in pulmonary vascular cells from patients with pulmonary hypertension (PH) led to comparisons with the Warburg effect in cancers, PH has joined the list of cardiovascular and respiratory disorders with a metabolic component to their pathology. Insulin resistance is common and associated with poor outcomes [1], and questions over the importance of prevalent metabolic syndrome remain [2]. Development of libraries of metabolites characterised with high throughput chromatography-mass spectrometry methods has facilitated the screening of large numbers of metabolites in disease tissue samples. Polyamine metabolism is a new target in pulmonary arterial hypertension also under development in cancer research <https://bit.ly/2YnD17o>
Healthcare should not cost us the Earth
Authors: Ruth Bennett, Jane Maraka
Journal: BMJ (2020)

The NHS announcing, during the covid-19 pandemic, its ambition to become the world’s first net zero emissions health service before 2050 is admirable.1 Although the pandemic has given us opportunities to reduce our carbon footprint, such as the rise of telemedicine,2 it has also placed some hidden environmental challenges on the NHS.

One cannot overlook the vast quantities of personal protective equipment (PPE) now required in excess of pre-covid levels. The …
Effect of Luspatercept on Biomarkers of Erythropoiesis in Patients (Pts) with Lower-Risk Myelodysplastic Syndromes (LR-MDS) in the Medalist Trial
Authors: Uwe Platzbecker, Yiming Zhu, Xianwei Ha, Alberto Risueño, Esther Chan, George Zhang, Diana R. Dunshee, Melih Acar, Jeevan K. Shetty, Rodrigo Ito, Kyle MacBeth, Valeria Santini, Maciej W. Garbowski, Pierre Fenaux, Martin Schwickart
Journal: Blood (2020)
Safety and Efficacy of Induction and Maintenance Avelumab Plus R-CHOP in Patients with Diffuse Large B-Cell Lymphoma (DLBCL): Analysis of the Phase II Avr-CHOP Study
Authors: Eliza A Hawkes, Geoffrey Chong, Charmaine Smith, Sze-Ting Lee, Leonid Churilov, Joseph McKendrick, William Renwick, Piers Blombery, Niles Elizabeth Nelson, Tineke Fancourt, Joanne Hawking, Wendi Lin, Andrew M Scott, Allison Barraclough, Joel Wight, Andrew Grigg, Colm Keane, Chun Yew Fong, Kate Manos
Journal: Blood (2020)