tbuckley/cabot-search huggingface dataset:
Real-World Experience of CPX-351 As First-Line Treatment in 188 Patients with Acute Myeloid Leukemia
Authors: Christina Rautenberg, Friedrich Stölzel, Christoph Röllig, Matthias Stelljes, Verena I Gaidzik, Michael Lauseker, Oliver Kriege, Mareike Verbeek, Julia M. Unglaub, Felicitas Thol, Stefan W. Krause, Mathias Haenel, Charlotte Neuerburg, Vladan Vucinic, Christian Jehn, Julia Severmann, Maxi Wass, Lars Fransecky, Jens Chemnitz, Udo Holtick, Kerstin Schäfer-Eckart, Josephine Schröder, Sabrina Kraus, William Hermann Krüger, Ulrich Kaiser, Sebastian Scholl, Lea Henning, Guido Kobbe, Rainer Haas, Nael Alakel, Maximilian Alexander Röhnert, Katja Sockel, Maher Hanoun, Uwe Platzbecker, Tobias A. W. Holderried, Anke Morgner, Michael Heuser, Tim Sauer, Katharina S. Goetze, Eva Maria Wagner, Konstanze Döhner, Hartmut Döhner, Christoph Schliemann, Johannes Schetelig, Martin Bornhäuser, Ulrich Germing, Thomas Schroeder, Moritz Moritz Middeke
Journal: Blood (2021)
Abstract 14218: Sex Differences in the Epidemiology of Thoracic Aortic Disease: A Population Based Study
Authors: Carly Lodewyks, Heather Prior, Brett Hiebert, Nathan Nickel, Maral Ouzounian, Kanwal Kumar, Rakesh Arora, Navdeep Tangri, Michael Yamashita
Journal: Circulation (2018)

Introduction: Thoracic aortic disease (TAD) has traditionally been reported as more common in males versus females. There is however, a lack of contemporary data examining the epidemiology of TAD s...
SY5609, a Potent and Selective CDK7 Inhibitor, Potentiates BTK Inhibitor Activity in Mantle Cell Lymphoma Preclinical Models
Authors: Liv Johannessen, Susan Henry, Priyanka Sawant, Anthony D'Ippolito, Nan Ke, Ariel Lefkowitz, Matthew Eaton, Wojciech Dworakowski, Maria Rosario, Graeme Hodgson
Journal: Blood (2021)
Immunophenotypic and Single-Cell Transcriptional Profiling of CD34+ Hematopoietic Stem and Progenitor Cells Mobilized with Motixafortide (BL-8040) and G-CSF Versus Plerixafor and G-CSF Versus Placebo and G-CSF: A Correlative Study of the Genesis Trial
Authors: Zachary D. Crees, Michael Retting, Reyka G Jayasinghe, Keith E. Stockerl-Goldstein, Abi Vainstein, Ella Sorani, Debby Ickowicz, Liron Shemesh-Darvish, Shaul Kadosh, John F. DiPersio
Journal: Blood (2021)
Pharmacokinetic / Pharmacodynamic (PK/PD) Simulations Guide Selection of the Dose for Administration of Efgartigimod Subcutaneously in a Phase 3 Clinical Trial in Patients with Primary Immune Thrombocytopenia
Authors: Waleed Ghanima, Vickie McDonald, Shivi Jain, Monica Carpenedo, Esther N. Oliva, Anna Hultberg, Domenica Gandini, Erik Hofman, Tonke Van Bragt, Wim Parys, Benjamin van Hoorick, Yoshitaka Miyakawa, Catherine M. Broome
Journal: Blood (2021)
Planned Interim Analysis of a Phase 2 Study of Loncastuximab Tesirine Plus Ibrutinib in Patients with Advanced Diffuse Large B-Cell Lymphoma (LOTIS-3)
Authors: Carmelo Carlo-Stella, Pier Luigi Luigi Zinzani, Murali Janakiram, Vivian Dia, Xiaomin He, Annette Ervin-Haynes, Julien Depaus
Journal: Blood (2021)
Improved GvHD-Free, Relapse-Free Survival (GRFS) with Post-Transplant Cyclophosphamide and Tacrolimus for GvHD Prevention in Older Adults Undergoing Allogeneic Hematopoietic Cell Transplantation
Authors: Paola Andrea Charry, Maria Queralt Salas, Alexandra Pedraza, María Suárez-Lledó, Nuria Martínez-Cibrian, Teresa Solano, Ariadna Domenech, Meritxell Nomdedeu, Joan Cid, Miquel Lozano, Laura Rosinol, Francesc Fernández-Avilés, Gonzalo Gutiérrez-García, Enric Carreras, Jordi Esteve, Álvaro Urbano-Ispizua, Montserrat Rovira, Carmen Martínez
Journal: Blood (2021)
A novel CD123-targeted therapeutic peptide loaded by micellar delivery system combats refractory acute myeloid leukemia
Authors: Shilin Xu, Meichen Zhang, Xiaocui Fang, Jie Meng, Haiyan Xing, Doudou Yan, Jian Liu, Yanlian Yang, Tao Wen, Weiqi Zhang, Jianxiang Wang, Chen Wang, Haiyan Xu
Journal: Journal of Hematology & Oncology (2021)

Abstract Acute myeloid leukemia (AML) is a common malignant heterogeneous hematopoietic disease with very low average 5-year survival rate due to the refractory feature and high rate of relapse. CD123 is highly expressed on multiple types of AML cells, especially leukemia stem cells, and closely associated with the poor prognosis of AML. Aiming to meet the urgent demand to targeted therapeutics for the refractory AML patients, herein we synthesize a CD123 antagonistic peptide (PO-6) loaded in nanomicelles ( m PO-6), and investigated its therapeutic effect and pharmacokinetics on a lab-established refractory AML mice model (AE &amp; CKIT D816V ). It is shown that the PO-6 can effectively bind to the CD123 + AML cells and the micellar formulation m PO-6 increases the dissolution stability and the specific binding capacity. When injected intravenously, m PO-6 significantly prolongs the survival of the refractory AML mice by interfering CD123/IL-3 axis, evidenced by the down regulation of phosphorylation of STAT5 and PI3K/AKT and the inhibition of activated NF-κB in the nucleus, as well as by the analysis results of next generation RNA-sequencing (RNA-seq) with the bone marrow of the AML mice. The antagonistic effect leads to the significantly reduction of AML cells infiltration in the bone marrow of the AML mice. In conclusion, m PO-6 could provide a potent antagonistic therapeutic approach for targeted treatment of AML.
Impact of Maintenance Arm on Prognostic Value of MRD after Induction Treatment in MCL R2 Elderly Trial , a Mantle Cell Lymphoma Network Study
Authors: Marie-Helene Delfau, Elizabeth A. Macintyre, Mary B. Callanan, Christiane Pott, Vincent H.J. Van Der Velden, Christa Homburg, Ramon Garcia-Sanz, Paula Gameiro, Maria Gomes Da Silva, Wolfram Klapper, Lucie Oberic, Pierre Feugier, Violaine Safar, Olivier Casasnovas, Martin H. Dreyling, Vincent Ribrag
Journal: Blood (2021)
Venetoclax for Acute Myeloid Leukemia in Pediatric Patients: A Texas Medical Center Collaboration
Authors: Adriana Trabal, Amber Gibson, David McCall, Kris M Mahadeo, Laurie Toepfer, Michael E. Roth, Meridith Buzbee, Tapan M. Kadia, Sofia Garces, Marina Konopleva, Courtney D. DiNardo, Naval Daver, Nicholas J. Short, Ghayas C. Issa, Farhad Ravandi, Cesar Nunez, Sajad J Khazal, Hana Paek, Julienne Brackett, Guillermo Garcia-Manero, Hagop Kantarjian, Andrea N Marcogliese, ZoAnn Dreyer, Michele S. Redell, Joanna S. Yi, Alexandra McLean Stevens, Branko Cuglievan
Journal: Blood (2021)
92 Single cell and spatial multiplex profiling of immune cell markers in FFPE tumor tissues using the novel RNAscope™ HiPlex v2 in situ hybridization assay
Authors: Sayantani Basak, Anushka Dikshit, Ming Yu, HaYeun Ji, Ching-Wei Chang, Bingqing Zhang
Journal: Journal for ImmunoTherapy of Cancer (2021)

Background The tumor microenvironment (TME) is highly complex, comprised of tumor cells, immune cells, stromal cells, and extracellular matrix. Understanding spatial interactions between various cell types and their activation states in the TME is crucial for implementing successful immunotherapy strategies against various types of cancer. This study demonstrates a highly sensitive and specific multiplexed technique, the RNAscope HiPlex v2 in situ hybridization (ISH) assay for spatial and transcriptomic profiling of target genes to assess immune regulation in human lung, breast, cervical and ovarian FFPE tumor tissues. Methods We have expanded our current RNAscope HiPlex assay capability of iteratively multiplexing up to 12 targets in fixed and fresh frozen samples to include formalin fixed paraffin embedded (FFPE) tissues. The novel FFPE reagent effectively reduces background autofluorescence, improving the signal to noise ratio. We have leveraged this technology to investigate spatial expression of 12 oncology and immuno-oncology target genes, including tumor markers, immune checkpoint markers, immunosuppression markers, immune cell markers and secreted chemokine RNA expression profile within the TME. The targets were simultaneously registered using HiPlex image registration software v2 that enables background subtraction. Results We visualized T cell infiltration and identified T cell subsets within tumors using CD3and CD8 expression and activated T cells by IFNG expression. We further identified subsets of pro- and anti-inflammatory macrophages by CD68 and CD163 expression as well effector cells which secrete chemokines and cytokine. We also detected the hypoxia markers HIF1A and VEGF to elucidate the immunosuppressive state of tumor cells. Preliminary analysis and quantification of the HIF1A expression using HALO® image analysis software showed higher copy numbers in the lung tumor as compared to the other tumors, demonstrating the sensitivity of the assay through differential expression. We additionally showed the differential expression of immune checkpoint markers PDCD1, and CD274 within the TME. Conclusions Using a highly sensitive multiplexed RNAscope HiPlex v2 ISH assay, we have demonstrated the capability of this technique to spatially resolve 12 targets in four different tumor types. The FFPE reagent efficiently quenched background autofluorescence in the tissues and identified immune cell signatures within the TME. Quantification of immunosuppressive markers further depicted a differential expression among various tumors. This technology is highly beneficial for investigating complex and spatial tumor-stroma interactions in basic science and translational research. The assay can also provide valuable understanding of the biological crosstalk among various cell types in complex and heterogeneous tissues.
Comparison of Prophylactic and Preemptive Donor Lymphocyte Infusion in Patients with Very High Risk Acute Leukemia after Allogeneic Hematopoietic Stem Cell Transplantation
Authors: Luxin Yang, Yi Luo, He Huang, Yamin Tan, Jimin Shi, Yanmin Zhao, Jian Yu, Xiaoyu Lai
Journal: Blood (2021)
CD66e Enrichment Enhances Repopulation of Human Long-Term Hematopoietic Stem Cells
Authors: Kuiying Ma, Riguo Fang, Lingling Yu, Yongjian Zhang, Chao Li, Zhongyu Shi, Huihui Yang, Penghui Xia, Xijuan Zhang, Wei Zhang, Pengfei Yuan, Dong Wei
Journal: Blood (2021)
Minor GPI(-) Granulocyte Populations in Patients with Acquired Aplastic Anemia and Healthy Individuals Are Derived from a Few <i>Piga</i>-Mutated Hematopoietic Stem Progenitor Cells
Authors: Hiroki Mizumaki, Dung Cao Tran, Kohei Hosokawa, Kazuyoshi Hosomichi, Hiroyuki Takamatsu, Hirohito Yamazaki, Atsushi Tajima, Ken Ishiyama, Shinji Nakao
Journal: Blood (2021)
Abstract 9307: A Heart of Gold: A Case Report of Massive Pericardial Effusion Secondary to Cholesterol Pericarditis
Authors: Lee Bockus, Kenta Nakamura, Michael A Chen
Journal: Circulation (2021)

A case of rare cholesterol pericarditis that developed over 12 years resulting in a massive pericardial effusion containing cholesterol crystals is described. A 41-year-old homeless man with history of polysubstance intravenous drug abuse and upper respiratory and soft-tissue infections presented with evidence of recurrent left lower extremity cellulitis, mild shortness of breath, and palpitations. Physical exam demonstrated soft-tissue infection, marked tachycardia and distant heart sounds on auscultation, and jugular venous distention. Unexpectedly, pulse-oximetry plethysmographic waveforms revealed pronounced respirophasic variability and pulsus paradoxus of 14 mmHg. Electrocardiogram demonstrated low voltage and electrical alternans. A transthoracic echocardiogram revealed a large pericardial effusion and findings consistent with tamponade physiology, such as elevated respiratory variation in mitral inflow velocity. Emergent pericardiocentesis yielded 3.6 L of fluid characterized by glittering, gold paint-like appearance and a cell count predominated by macrophages, leading to a provisional diagnosis of cholesterol pericarditis. This was confirmed by polarized light microscopy demonstrating cholesterol crystals. Retrospective review of prior emergency department visits revealed a 12-year development of the effusion, beginning with symptoms, imaging, and labs consistent with a presumably instigating viral respiratory illness. Over time, progressive enlargement and evidence of chronic pericarditis were demonstrated by chest x-ray and electrocardiography, while the effusion remained undiagnosed. Following improvement in his symptoms after pericardiocentesis, the patient deferred pericardial window and definitive surgical management with pericardiectomy. Given his high risk for recurrent cardiac tamponade, he was given clear return precautions and is now followed on an outpatient basis. The diverse etiologies of cholesterol pericarditis, such as hypothyroidism, tuberculosis, and rheumatoid arthritis, that guided the workup for this patient, and the pathophysiology of this disease and its treatment options, are reviewed.
DREAM: a database of experimentally supported protein-coding RNAs and drug associations in human cancer
Authors: Shupeng Li, Lulu Li, Xiangqi Meng, Penggang Sun, Yi Liu, Yuntang Song, Sijia Zhang, Chuanlu Jiang, Jinquan Cai, Zheng Zhao
Journal: Molecular Cancer (2021)

Abstract The Drug Response Gene Expression Associated Map, also referred as “DREAM” ( http://bio-big-data.cn:8080/DREAM ), is a manually curated database of experimentally supported protein-coding RNAs and drugs associations in human cancers. The current version of the DREAM documents 3048 entries about scientific literatures supported drug sensitivity or drug intervention related protein-coding RNAs from PubMed database and 195 high-throughput microarray data about drug sensitivity or drug intervention related protein-coding RNAs data from GEO database. Each entry in DREAM database contains detailed information on protein-coding RNA, drug, cancer, and other information including title, PubMed ID, journal, publish time. The DREAM database also provides some data visualization and online analysis services such as volcano plot, GO/KEGG enrichment function analysis, and novel drug discovery analysis. We hope the DREAM database should serve as a valuable resource for clinical practice and basic research, which could help researchers better understand the effects of protein-coding RNAs on drug response in human cancers.
ATRX regulates glial identity and the tumor microenvironment in IDH-mutant glioma
Authors: Husam Babikir, Lin Wang, Karin Shamardani, Francisca Catalan, Sweta Sudhir, Manish K. Aghi, David R. Raleigh, Joanna J. Phillips, Aaron A. Diaz
Journal: Genome biology (2021)

Abstract Background Recent single-cell transcriptomic studies report that IDH-mutant gliomas share a common hierarchy of cellular phenotypes, independent of genetic subtype. However, the genetic differences between IDH-mutant glioma subtypes are prognostic, predictive of response to chemotherapy, and correlate with distinct tumor microenvironments. Results To reconcile these findings, we profile 22 human IDH-mutant gliomas using scATAC-seq and scRNA-seq. We determine the cell-type-specific differences in transcription factor expression and associated regulatory grammars between IDH-mutant glioma subtypes. We find that while IDH-mutant gliomas do share a common distribution of cell types, there are significant differences in the expression and targeting of transcription factors that regulate glial identity and cytokine elaboration. We knock out the chromatin remodeler ATRX, which suffers loss-of-function alterations in most IDH-mutant astrocytomas, in an IDH-mutant immunocompetent intracranial murine model. We find that both human ATRX-mutant gliomas and murine ATRX-knockout gliomas are more heavily infiltrated by immunosuppressive monocytic-lineage cells derived from circulation than ATRX-intact gliomas, in an IDH-mutant background. ATRX knockout in murine glioma recapitulates gene expression and open chromatin signatures that are specific to human ATRX-mutant astrocytomas, including drivers of astrocytic lineage and immune-cell chemotaxis. Through single-cell cleavage under targets and tagmentation assays and meta-analysis of public data, we show that ATRX loss leads to a global depletion in CCCTC-binding factor association with DNA, gene dysregulation along associated chromatin loops, and protection from therapy-induced senescence. Conclusions These studies explain how IDH-mutant gliomas from different subtypes maintain distinct phenotypes and tumor microenvironments despite a common lineage hierarchy.
Seven steps toward more transparency in statistical practice
Authors: Eric-Jan Wagenmakers, Alexandra Sarafoglou, Sil Aarts, Casper Albers, Johannes Algermissen, Štěpán Bahník, Noah van Dongen, Rink Hoekstra, David Moreau, Don van Ravenzwaaij, Aljaž Sluga, Franziska Stanke, Jorge Tendeiro, Balazs Aczel
Journal: Nature Human Behaviour (2021)

We argue that statistical practice in the social and behavioural sciences benefits from transparency, a fair acknowledgement of uncertainty and openness to alternative interpretations. Here, to promote such a practice, we recommend seven concrete statistical procedures: (1) visualizing data; (2) quantifying inferential uncertainty; (3) assessing data preprocessing choices; (4) reporting multiple models; (5) involving multiple analysts; (6) interpreting results modestly; and (7) sharing data and code. We discuss their benefits and limitations, and provide guidelines for adoption. Each of the seven procedures finds inspiration in Merton's ethos of science as reflected in the norms of communalism, universalism, disinterestedness and organized scepticism. We believe that these ethical considerations—as well as their statistical consequences—establish common ground among data analysts, despite continuing disagreements about the foundations of statistical inference. Wagenmakers and colleagues describe seven statistical procedures that increase transparency in data analysis. These procedures highlight common ground among data analysts from different schools and find inspiration in Merton's ethos of science.
Preclinical models of idiosyncratic drug-induced liver injury (iDILI): Moving towards prediction
Authors: Antonio Segovia-Zafra, Daniel E. Di Zeo-Sánchez, Carlos López-Gómez, Zeus Pérez-Valdés, Eduardo García-Fuentes, Raúl J. Andrade, M. Isabel Lucena, Marina Villanueva-Paz
Journal: Acta Pharmaceutica Sinica B (2021)

Idiosyncratic drug-induced liver injury (iDILI) encompasses the unexpected harms that prescription and non-prescription drugs, herbal and dietary supplements can cause to the liver. iDILI remains a major public health problem and a major cause of drug attrition. Given the lack of biomarkers for iDILI prediction, diagnosis and prognosis, searching new models to predict and study mechanisms of iDILI is necessary. One of the major limitations of iDILI preclinical assessment has been the lack of correlation between the markers of hepatotoxicity in animal toxicological studies and clinically significant iDILI. Thus, major advances in the understanding of iDILI susceptibility and pathogenesis have come from the study of well-phenotyped iDILI patients. However, there are many gaps for explaining all the complexity of iDILI susceptibility and mechanisms. Therefore, there is a need to optimize preclinical human in vitro models to reduce the risk of iDILI during drug development. Here, the current experimental models and the future directions in iDILI modelling are thoroughly discussed, focusing on the human cellular models available to study the pathophysiological mechanisms of the disease and the most used in vivo animal iDILI models. We also comment about in silico approaches and the increasing relevance of patient-derived cellular models.
Treatment of Patients with Relapsed or Refractory Primary CNS Lymphoma (rrPCNSL) Enrolled in the Randomized Trials of the International Extranodal Lymphoma Study Group (IELSG)
Authors: Andrés J M Ferreri, Kate Cwynarski, Elisa Pulczynski, Christopher P. Fox, Paul La Rosée, Elisabeth Schorb, Mauro Krampera, Fiorella Ilariucci, Lorella Orsucci, Alberto Fabbri, Alessandra Tucci, Alexander Roeth, Kim Linton, Mascha Binder, Claire Hemmaway, Maria Giuseppina Cabras, Antonio Pinto, Teresa Calimeri, Franco Cavalli, Emanuele Zucca, Gerald Illerhaus
Journal: Blood (2021)
Anti-CD117 CAR T Cells Incorporating a Safety Switch Eradicate Acute Myeloid Leukemia and Deplete Human Hematopoietic Stem Cells
Authors: Chiara F Magnani, Renier Myburgh, Norman F Russkamp, Steve Pascolo, Judith A Shizuru, Dario Neri, Markus G Manz
Journal: Blood (2021)
Abstract 13598: Neutrophil Extracellular Traps (NETs) Promote Macrophage Inflammation and Contribute to Diabetes-Impaired Atherosclerosis Regression
Authors: Tatjana Josefs, Tessa Barrett, Emily Brown, Alexandra Quezada, Yoscar Ogando, Felix Zhou, Edward A Fisher
Journal: Circulation (2019)

The contribution of neutrophils to atherosclerosis is understudied. Recently NETs have been shown in mouse and human plaques, where they are thought to promote atherosclerosis progression by primin...
Patient-Reported Outcomes in Long-Term Survivors of Autologous Hematopoietic Cell Transplantation for Multiple Myeloma: Secondary Analysis of Two Randomized Controlled Trials on Survivorship Care Plans
Authors: Rajshekhar Chakraborty, Lisa A. Rybicki, Jaime M. Preussler, Steven Devine, K. Scott Baker, Karen Syrjala, Jean C. Yi, Jennifer L Whitten, Bronwen E. Shaw, Navneet S. Majhail
Journal: Blood (2021)
Moderate Intensity Exercise Training Improves Skeletal Muscle Performance in Symptomatic and Asymptomatic Statin Users
Authors: Neeltje A.E. Allard, Lando Janssen, Thorben Aussieker, Anouk A.F. Stoffels, Richard J. Rodenburg, Willem J.J. Assendelft, Paul D. Thompson, Tim Snijders, Maria T.E. Hopman, Silvie Timmers
Journal: Journal of the American College of Cardiology (2021)
Analysis of Early Events during the First Year of Tyrosine Kinase Inhibitor Therapy in Patients with Chronic Phase - Chronic Myeloid Leukemia: A "Campus CML" Study
Authors: Mario Tiribelli, Isabella Capodanno, Maria Cristina Miggiano, Cristina Bucelli, Francesco Cavazzini, Sabrina Leonetti Crescenzi, Sabina Russo, Emilia Scalzulli, Andrea Bernardelli, Luigiana Luciano, Olga Mulas, Giuseppina Loglisci, Chiara Elena, Umberto Pizzano, Immacolata Attolico, Gianni Binotto, Elena Crisà, Paolo Sportoletti, Ambra Di Veroli, Anna Rita Scortechini, Annapaola Leporace, Maria Basile, Monica Crugnola, Fabio Stagno, Pamela Murgano, Davide Rapezzi, Alessandra Malato, Michele Pizzuti, Debora Luzi, Malgorzata Monika Trawinska, Alessandra Iurlo, Monica Bocchia, Carmen Fava, Giovanni Caocci, Massimiliano Bonifacio, Giuseppe Nicola Saglio, Giorgina Specchia, Massimo Breccia, Roberto Latagliata
Journal: Blood (2021)
High Dose Flamsa, CLAG or FLAG-Based Sequential Conditioning Regimen Followed By Allogeneic Hematopoietic Transplantation Results in Favorable Outcome for High Risk Acute Myeloid Leukemia, Myelodysplastic Syndrome, Myeloproliferative Neoplasia Patients : A Multicenter Study in Singapore
Authors: Lip Leong Chong, Yang Liang Boo, Yin Jie Koh, Michelle Poon, Yeh Ching Linn, William YK Hwang, Aloysius YL Ho, Elson Neo, Lip Kun Tan, Liang Piu Koh
Journal: Blood (2020)
Non-Classical Monocyte Abundance Is an Independent Adverse Risk Factor for Relapse in Pediatric B-ALL
Authors: Gloria Paz Contreras Yametti, Nikki Ann Evensen, Meenakshi Devidas, Elizabeth A. Raetz, Karen R Rabin, David T. Teachey, Iannis Aifantis, William L. Carroll, Matthew Witkowski
Journal: Blood (2021)
A Phase 3, Randomized, Double-Blinded Study of Four-Factor Prothrombin Complex Concentrate in Patients with Acute Major Bleeding on Direct Oral Anticoagulant Therapy with Factor Xa Inhibitor: The Lex-210 Study
Authors: Ravi Sarode, Stephan Maack, Cristina Solomon, Sigurd Knaub, Sam Schulman
Journal: Blood (2021)
Microtubule Polymerization Inhibition Enhances Human Hematopoietic Stem Cell Homing and Engraftment
Authors: Kuiying Ma, Riguo Fang, Lingling Yu, Chao Li, Zhongyu Shi, Huihui Yang, Penghui Xia, Xijuan Zhang, Yongjian Zhang, Wei Zhang, Pengfei Yuan, Dong Wei
Journal: Blood (2021)
Risk Stratification for Acute Arterial and Venous Thromboembolism using CHA 2DS 2-VASc Score in Hospitalized COVID-19 Patients: A Multicenter Study
Authors: Yi Lee, Qasim Jehangir, Pin Li, Chun-Hui Lin, Anupam A Sule, Geetha Krishnamoorthy, Judie R Goodman, Abdul Halabi, Kiritkumar Patel, Dee Dee Wang, Laila Poisson, Girish B Nair
Journal: Blood (2021)