tbuckley/cabot-search huggingface dataset:
Leads from the MMWR. Update: serologic testing for antibody to human immunodeficiency virus
Journal: JAMA (1988)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Sixteenth Midyear Topical Symposium of the Health Physics Society
Journal: JNCI Journal of the National Cancer Institute (1982)

Sixteenth Midyear Topical Symposium of the Health Physics Society Get access JNCI: Journal of the National Cancer Institute, Volume 69, Issue 1, July 1982, Page 318, https://doi.org/10.1093/jnci/69.1.318-b Published: 01 July 1982
THE MINIMAL FAT RATION
Journal: JAMA (1918)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Dabrafenib Effective in Pediatric Glioma
Journal: Cancer Discovery (2016)

A phase I/II clinical trial suggests that dabrafenib shrinks or stabilizes low-grade gliomas in children with the BRAF V600E mutation. Objective, durable responses occurred in 38% of patients, and the side effects were less severe than with chemotherapy. The researchers have started a second trial for patients with glioma and other BRAF-mutant tumor types, this time evaluating dabrafenib combined with trametinib.
Vestnik Otorinolaringologii, Moscow
Journal: JAMA (1967)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Erratum: Generation of functional hepatocytes from human embryonic stem cells under chemically defined conditions that recapitulate liver development
Authors: Thomas Touboul, Nicholas R. F. Hannan, Sébastien Corbineau, Amélie Martinez, Clémence Martinet, Sophie Branchereau, Sylvie Mainot, Hélène Strick-Marchand, Roger Pedersen, James Di Santo, Anne Weber, Ludovic Vallier
Journal: Hepatology (2010)

In the May 2010 issue of HEPATOLOGY, regarding the article titled “Generation of Functional Hepatocytes from Human Embryonic Stem Cells Under Chemically Defined Conditions that Recapitulate Liver Development” (HEPATOLOGY 2010;51:1754-1765), the author's affiliations were ordered incorrectly. The correct affiliations are: Thomas Touboul,1,2 Nicholas R. F. Hannan,3* Sébastien Corbineau,1,2* Amélie Martinez,1,2 Clémence Martinet,1,2 Sophie Branchereau,1,4 Sylvie Mainot,1,2 Hélène Strick-Marchand,5 Roger Pedersen,3 James P. Di Santo,5 Anne Weber,1,2* and Ludovic Vallier3* From the 1Institut National de la Santé et de la Recherche Médicale (INSERM), Unite 972, IFR 93, Bicêtre Hospital, Kremlin-Bicêtre, France; 2Université Paris-Sud, Orsay, France; 3Department of Surgery, The Anne McLaren Laboratory for Regenerative Medicine, Cambridge, UK; 4Department of Surgery, Bicêtre Hospital, Assistance Publique–Hopitaux de Paris, Kremlin-Bicêtre, France; 5INSERM Unite 668, Cytokines and Lymphoid Development Unit, Institut Pasteur, Paris, France. The following funding was omitted: EC MUGEN Network of Excellence grant LSHG-CT-2005-005203 (to J.P.D.) The following sentence was omitted: L.V. and A.W. share last authorship.
Invitation to a single FS screening vs. usual care reduced colorectal cancer mortality and incidence at &gt;15 y
Authors: David B. King
Journal: Annals of Internal Medicine (2022)

Senore C, Riggi E, Armaroli P, et al. Long-term follow-up of the Italian flexible sigmoidoscopy screening trial. Ann Intern Med. 2022;175:36-45. 34748376.
Global Cancer Burden Grew From 2010 to 2019
Authors: Anita Slomski
Journal: JAMA (2022)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
<i>Erratum</i>: Vol. 70, No. 27
Authors: Meredith Dixon, Caitlyn Lutfy
Journal: MMWR Morbidity and Mortality Weekly Report (2021)

On page 970, in Table 3, in the row for "Social participation ability," in the columns for "Post-COVID-19 patients," "Control patients," and "mean difference" the summary scale T-score mean standard deviations and mean differences should have read, "46.6 (44.7 to 48.6)," "50.5 (50.0 to 51.1)," and " -4.2 (-6.4 to -2.0)," respectively.
Low-grade appendiceal mucinous neoplasms observed by magnifying endoscopy
Authors: Kengo Kasuga, Keigo Sato, Yu Hashimoto, Hirohito Tanaka, Hiroko Hosaka, Shiko Kuribayashi, Toshio Uraoka
Journal: Endoscopy (2022)

Appendiceal mucinous neoplasms are the second most common tumors after carcinoid tumors in all excised appendices [1]. Low-grade appendiceal mucinous neoplasms are often found incidentally (~50 %), first discovered on radiography, endoscopy, or during surgery [2]. On endoscopy, they often appear as submucosal tumor-like elevations at the appendicular orifice [3]; there are no reports of associated epithelial changes. Herein we report two cases of endoscopically observed epithelial changes in low-grade appendiceal mucinous neoplasms ([Video 1]).
Clinical Connections
Journal: Arthritis & Rheumatology (2020)

Uropathogenic Escherichia coli (UPEC) are known to cause urinary tract infections (UTIs) and form biofilms, which are multicellular communities of bacteria that are strengthened by amyloids such as curli.Curli form complexes with bacterial extracellular DNA (eDNA) and trigger lupus-like autoimmunity in mouse models.Pachucki et al investigated the antibody response to curli/eDNA complexes in humans and the role of anti-curli/eDNA antibodies in the pathogenesis of systemic lupus erythematosus (SLE) or development of an acute increase of severity (so-called flares).
Selected New Books
Journal: JAMA (1978)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Book: +/- Nothing A Heartbreaking Work of Staggering Genius
Authors: J. Quin
Journal: BMJ (2001)

Paul Morley Faber and Faber, £11.99, pp 426 ISBN 0 571 17799 9 Dave Eggers Picador, £14.99, pp 395 ISBN 0 330 48454 0 Rating: ![Graphic][1]</img>![Graphic][2]</img>![Graphic][3]</img>; ![Graphic][4]</img>![Graphic][5]</img>![Graphic][6]</img>![Graphic][7]</img> You have only to watch the news to see the modern media's take on ordinary human tragedy. The media sweeten the distress and horror, turning it into entertainment. The modern talk show, an oily slick of self disclosure, shows no sign of disappearing from our televisions. With this in mind, how might … [1]: /embed/inline-graphic-1.gif [2]: /embed/inline-graphic-2.gif [3]: /embed/inline-graphic-3.gif [4]: /embed/inline-graphic-4.gif [5]: /embed/inline-graphic-5.gif [6]: /embed/inline-graphic-6.gif [7]: /embed/inline-graphic-7.gif
Electron Microscope—Medicine's Research Tool of Unfulfilled Promise
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Table of contents
Authors: Melanie Shadoan, Mary Anthony, Samuel Rankin, Thomas Clarkson, Janice Wagner, D Spampinato, A Giaccari, V Trischitta, B Costanzo, L Morviducci, A Buongiorno, U Mario, R Vigneri, L Frittitta, Chisato Murata, Tetsu Watanabe, Hiroyuki Furuya, Yoshihiko Sugioka, Hajime Mikurube, Akira Yokoyama, Yoshihito Atsumi, Kempei Matsuoka, Isao Okazaki, Kay Ohlendieck, Shona Harmon, Michael Koll, Alistair Paice, Victor Preedy, Tsutomu Kazumi, Akira Kawaguchi, Tsutomu Hirano, Gen Yoshino, A Pascual-Leone, S Ramos, L Goya, C Alvarez, F Escriva, M Obrego ´n
Journal: Metabolism (2003)
Thwarting thrombogenesis on artificial surfaces
Authors: P. Gunby
Journal: JAMA (1982)

The usefulness of heart-lung machines, synthetic vascular grafts, and other cardiovascular replacement or support devices is undisputed, but they share a common disadvantage: Thrombi may form on the artificial surfaces, interfering with the device itself or eventually lodging in one of the patient's organs. The problems begin, says Edwin W. Salzman, MD, professor of surgery at Harvard Medical School and Beth Israel Hospital, Boston, when "certain proteins carried in the plasma—fibrinogen is one of the most important—are selectively deposited on a surface in a thin coat. "It is this thin film of protein," he told a recent American Heart Association seminar, "not the surface of the artificial material, that influences other blood proteins and platelets to find the surface attractive or unattractive and thus thrombogenic or thromboresistant." There are two possible ways to cope with this, and Salzman's group is studying both. One is to develop artificial surfaces that are
Table of contents
Journal: Hepatology (2021)

Cover Figure : In this issue, Schultheiß et al. dissect the pathological immune architecture of autoimmune hepatitis (AIH), a chronic inflammatory disease that regularly relapses when immunosuppression is tapered.Intriguingly, the T cell immune architecture appeared unaffected by immunosuppressive treatment and persisted in biochemical disease remission.This suggests that immunosuppressive treatment temporarily acts on T cell functionality, but leaves unaffected the underlying pathological immune architecture that is likely responsible for the high relapse rate in this disease.The cover image created by artist Dirk Streitenfeld illustrates this idea by showing a neglected piece of architecture superficially refurbished by new color without, however, fixing the structural integrity of the building.See article on page 1436.
Low-osmolar contrast agents
Journal: JAMA (1989)

<h3>To the Editor.—</h3> The total adoption of low-ionic contrast media is not likely, given the current economic limitations in this country. However, Dr Fischer's<sup>1</sup>statement in his recent editorial that a universal changeover to these agents is not justified just to increase patient comfort may be misconstrued as a statement, potentially with legal ramifications, that these drugs are not indicated when they are to be used primarily to lessen pain and motion during radiographic procedures. This is certainly not the case. In my practice, I have no doubt that the decrease in the pain that patients experience during intra-arterial injection of high concentrations of the new, more expensive, agents, compared with the intense pain commonly experienced with the older high-osmolality drugs, warrants their routine use for almost all diagnostic and interventional angiographic procedures. I cannot ethically deny their use to my patients, since I would insist on the use
Re: Oscar Reig Torras, Akhilesh Mishra, Alana Christie, et al. Molecular Genetic Determinants of Shorter Time on Active Surveillance in a Prospective Phase 2 Clinical Trial in Metastatic Renal Cell Carcinoma. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2021.12.003
Authors: Zhan Wang, Yang Zhao, Yushi Zhang
Journal: European Urology (2022)
Commentary
Authors: Peter D. Siersema
Journal: Endoscopy (2022)

Esophageal leaks can be effectively managed by self-expanding metal stent placement. However, safe stent removal may be complicated, especially in cases where the stent has become embedded in the esophageal wall. The authors in this E-Video were successful in removing an embedded stent that had also partially migrated into the mediastinum. The remaining leak was successfully closed with endoluminal vacuum therapy (EVT).
Accelerating the Growth of Antibiotic Stewardship in Nursing Homes
Authors: Lindsay N. Taylor, Christopher J. Crnich
Journal: JAMA Network Open (2022)

Morgan J. Katz, MD, MHS; Pranita D. Tamma, MD, MHS; Sara E. Cosgrove, MD, MS; Melissa A. Miller, MD, MS; Prashila Dullabh, MD; Therese A. Rowe, DO; Roy Ahn, MPH, ScD; Kathleen Speck, MPH; Yue Gao, MPH; Savyasachi Shah, BDS, MPH; Robin L. P. Jump, MD, PhD
Discussion: session 1. Detection of health effects of exposure to low doses of agents—scientific constraints
Authors: Edward Radford, Nurtan Esmen, Yves Alarie
Journal: Environmental Health Perspectives (1981)

The discussion opened with consideration of the suitability of animal models for extrapolation to human disease.Dr. Alarie pointed out that for some carcinogens, such as vinyl chloride, animal data had proved to be quite predictive of human effects.He commented that methods developed by Dow Chemical Company in studying uptake and excretion of several chemicals had taken account of metabolic differences between animals and man, when the human data were available.He also believes that by means of kinetic models, for at least some inhaled chemicals, it will be possible in the next few years to estimate human effects from animal data in reasonably quantitative terms.Dr. Land mentioned that for a physical agent such as ionizing radiation, animal data were useful for studying mechanisms of action.There followed discussion of the comparability of routes of exposure.Dr. Julian Andelman (Univer- sity of Pittsburgh) asked if inhalation exposure limits could give guidance to exposure limits for chemicals in water or food.There was general agreement by Drs.Esmen and Alarie that for some materials which are absorbed and metabolized in the same way, regardless of route of entry, this approach was reasonable, but in general such
Bidirectional recanalization of a complete postradiation stricture of the hypopharynx and esophagus.
Authors: Georgios Mavrogenis, Fateh Bazerbachi, Konstantinos Markoglou, Sandro Porceddu, Sunil Gupta, Luke Hourigan
Journal: Endoscopy (2022)

A 65-year-old patient was referred for endoscopic management of a complete radiation-induced stricture, 5 cm in length, of the hypopharynx and esophagus ([Fig. 1], [Video 1]). He had a history of curative chemoradiation therapy for T2N1 squamous cell carcinoma of the larynx. His nutrition was exclusively maintained through a percutaneous gastrostomy. Recanalization of the esophagus was considered after a multidisciplinary discussion, as previously described [1] [2] [3].
Liver regeneration in fulminant hepatitis as evaluated by serum transforming growth factor ? levels
Authors: T Tomiya, K Fujiwara
Journal: Hepatology (1996)

Transforming growth factor α (TGF α) is supposed to act as a mitogen for hepatocytes in an autocrine manner in vitro and in vivo . Retarded liver regeneration is a possible reason for poor prognosis of fulminant hepatitis (FH). We analyzed serum TGF α levels in patients with FH and patients with acute nonfulminant hepatitis (AH). Also, the relation of those levels to serum hepatocyte growth factor (HGF) levels and their changes after glucagon-insulin (G-I) therapy were studied. Maximal serum TGF α levels achieved in each case after admission until recovery from disease or death were correlated positively with maximal serum alanine transaminase (ALT) and total bilirubin levels in patients with AH, but negatively with maximal total bilirubin levels in patients with FH. Maximal serum TGF α levels in patients with FH were significantly higher in survivors than in nonsurvivors. Maximal serum HGF levels were positively correlated with maximal serum TGF α levels in patients with AH, but not in patients with FH. Multiple regression analysis indicated that G-I therapy was related to the increment of serum TGF α levels in patients with FH. These results suggest that serum TGF α levels are increased in accordance with liver regeneration after necrosis in patients with AH, but such liver regeneration may be retarded, depending on the extent of liver damage in patients with FH. G-I therapy seems to stimulate liver regeneration after liver damage. The possible contribution of TGF α and HGF to liver regeneration merits consideration for recovery from AH.
Augmented cellular uptake and homologous targeting of exosome-based drug loaded IOL for posterior capsular opacification prevention and biosafety improvement
Authors: Siqing Zhu, Huiying Huang, Dong Liu, Shimin Wen, Liangliang Shen, Quankui Lin
Journal: Bioactive Materials (2022)

Posterior capsular opacification (PCO), the most common complication after cataract surgery, is caused by the proliferation, migration and differentiation of residual lens epithelial cells (LECs) on the surface of the intraocular lens (IOL). Although drug-loaded IOLs have been successfully developed, the PCO prevention efficacy is still limited due to the lack of targeting and low bioavailability. In this investigation, an exosome-functionalized drug-loaded IOL was successfully developed for effective PCO prevention utilizing the homologous targeting and high biocompatibility of exosome. The exosomes derived from LECs were collected to load the anti-proliferative drug doxorubicin (Dox) through electroporation and then immobilized on the aminated IOLs surface through electrostatic interaction. In vitro experiments showed that significantly improved cellular uptake of Dox@Exos by LECs was achieved due to the targeting ability of exosome, compared with free Dox, thus resulting in superior anti-proliferation effect. In vivo animal investigations indicated that Dox@Exos-IOLs effectively inhibited the development of PCO and showed excellent intraocular biocompatibility. We believe that this work will provide a targeting strategy for PCO prevention through exosome-functionalized IOL.