CHRONIC LEUKEMIA OF LONG DURATION: WITH A REPORT OF 31 CASES WITH A DURATION OF OVER FIVE YEARS
Authors: H C MOFFITT, J H LAWRENCE
Journal: Annals of Internal Medicine (1949)

Article1 April 1949CHRONIC LEUKEMIA OF LONG DURATION: WITH A REPORT OF 31 CASES WITH A DURATION OF OVER FIVE YEARSHERBERT C. MOFFITT JR., M.D., JOHN H. LAWRENCE, M.D., D.SC.HERBERT C. MOFFITT JR., M.D.Search for more papers by this author, JOHN H. LAWRENCE, M.D., D.SC.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-30-4-778 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptNumerous physicians have observed cases of leukemia of unusually long duration, but there is no published summary of many such cases. An analysis of unusual cases might add to knowledge of leukemia as a whole. Also if one could determine what factors lead to an unusually long duration, prognosis would be easier and therapy could be evaluated more readily. It therefore seems worthwhile to review the literature as it pertains to cases of leukemia of long duration and to select a group of such cases, from those seen by us, for analysis.DETERMINATION OF DURATIONThe determination of duration presents...Bibliography1. ARENDTGLOOR JW: Resultate der Rontgenbestrahlung bei chronischen Leukamien, Strahlentherapie, 1932, xliv, 715-738. Google Scholar2. BETHELL FH: Lymphogenous leukemia: Diagnostic, prognostic, and therapeutic considerations based on an analysis of its morphologic and clinical variants, Jr. Am. Med. Assoc., 1942, cxviii, 95-99. CrossrefGoogle Scholar3. BETHELLSTURGISRUNDLESMEYERS FHCCRWMC: Progress in internal medicine: blood, Arch. Int. Med., 1946, lxxvii, 80-119. CrossrefGoogle Scholar4. CRAVER LF: Clinical manifestations and treatment of leukemia, Am. Jr. Cancer, 1936, xxvi, 124-136. CrossrefGoogle Scholar5. FORKNER CE: Leukemia and Allied Disorders, 1938, Macmillan Co., New York. CrossrefGoogle Scholar6. FOWLER WM: Hematology, 1945, Paul B. Hoeber, Inc., New York. Google Scholar7. GLOOR W: Ein Fall von geheilter Myeloblastenleukamie, Munchen. med. Wchnschr., 1930, lxxvii, 1096-1098. Google Scholar8. HADEN RL: The leukemias, Cleveland Clin. Quart., 1944, xi, 55-62. CrossrefGoogle Scholar9. HEINLEWEIR RWDR: Morphologic obliteration of chronic myeloid leukemia by active tuberculosis. Report of a case, Am. Jr. Med. Sci., 1944, ccvii, 450-453. CrossrefGoogle Scholar10. HERZ A: Infektionen mit leukamischem Blutbild, Wien. klin. Wchnschr., 1926, xxxix, 835-837. Google Scholar11. HOFFMANCRAVER WJLF: Chronic myelogenous leukemia: Value of irradiation and its effect on the duration of life, Jr. Am. Med. Assoc., 1931, xcvii, 836-840. CrossrefGoogle Scholar12. JACKSONPARKERROBBCURTIS HFGPH: A case of acute leukemia with five months remission, Folia haemat., 1931, xliv, 30-37. Google Scholar13. JACKSON H: Acute leukemia with remissions, Proc. Am. Assoc. Cancer Res., Am. Jr. Canc., 1936, xxvi, 194-195. Google Scholar14. JACKSON H: The protean character of the leukemias and of the leukemoid states, New England Jr. Med., 1939, ccxx, 175-181. CrossrefGoogle Scholar15. JACKSON H: Report on medical progress: The leukemias, New England Jr. Med., 1940, ccxxii, 22-28. CrossrefGoogle Scholar16. LAWRENCEDOBSONLOW-BEERBROWN JHRLBVBR: Chronic myelogenous leukemia. A study of 129 cases in which treatment was with radioactive phosphorus, Jr. Am. Med. Assoc., 1948, cxxxvi, 672-677. CrossrefGoogle Scholar16a. LAWRENCE JH: Chronic lymphatic leukemia: a study of 100 cases treated with radioactive phosphorus. In press, Jr. Am. Med. Assoc. Google Scholar17. LEAVELL BS: Chronic leukemia. Study of incidence and factors influencing duration of life, Am. Jr. Med. Sci., 1938, cxcvi, 329-340. CrossrefGoogle Scholar18. LEBONMANCEAUXBLONDEAUALCAYSOUSSAL : Lymphemie subleucemique. Radiotherapie. Noma. Guerison clinique et hematologique remontant a 7 mois, Algerie med., 1934, xxxviii, 309. Google Scholar19. LECENE P: Un cas de "chlorome" de l'extremite superieure de l'humerus traite par la resection etendue. Guerison maintenue au bout de onze mois, Bull. et mém. Soc. nat. de chir., 1927, liii, 1328. Google Scholar20. LEUCUTIA T: Irradiation in lymphosarcoma, Hodgkin's disease and leukemia, statistical analysis, Am. Jr. Med. Sci., 1934, clxxxviii, 612-623. Google Scholar21. MARCUS IH: Complete temporary recovery, of long duration, in acute aleucemic myeloid leucemia, Jr. Lab. and Clin. Med., 1936, xxi, 1006-1009. Google Scholar22. MCGAVRAN CW: Lymphatic leukemia of 25 years' duration, Ann. Int. Med., 1938, xii, 396-402. Google Scholar23. MILLERTURNER FRDL: The leukemias, Med. Clin. North Am., 1944, xxviii, 1376-1385. CrossrefGoogle Scholar24. MINOTBUCKMANISAACS GRTER: Chronic myelogenous leukemia; age incidence, duration and benefit derived from irradiation, Jr. Am. Med. Assoc., 1924, lxxxii, 1489-1494. CrossrefGoogle Scholar25. MINOTISAACS GRR: Lymphatic leukemia; age incidence, duration, and benefit derived from irradiation, Boston Med. and Surg. Jr., 1924, cxci, 1-9. CrossrefGoogle Scholar26. MINOT GR: A non-fatal case simulating acute leukemia with anemia and thrombopenic purpura, Med. Clin. North Am., 1929, xiii, 1-9. Google Scholar27. MOESCHLIN S: Subakute paramyeloblasten Leukamien mit mehrfachen langeren Remissionen, Deutsch. Arch. f. klin. Med., 1943, cxci, 213. Google Scholar28. PASCUCCI LM: Chronic leukemia: A statistical study of symptoms, duration of life, and prognosis, Radiology, 1942, xxxix, 75-80. CrossrefGoogle Scholar29. PIERCE M: Childhood leucemia, Jr. Pediat., 1936, viii, 66-95. CrossrefGoogle Scholar30. RAPPOPORTKUGEL AEVH: Monocytic leukemia. A case report illustrating variations in the clinical picture, Blood, 1947, ii, 332-355. CrossrefGoogle Scholar31. REINHARDMOOREBIERBAUMMOORE EHCVOSS: Radioactive phosphorus as a therapeutic agent. A review of the literature and analysis of the results of treatment of 155 patients with various blood dyscrasias, lymphomas, and other malignant neoplastic diseases, Jr. Lab. and Clin. Med., 1946, xxxi, 107-215. Google Scholar32. RICHARDSMOENCH GGLG: Chronic lymphatic leukemia. Report of a case with survival for 16 years, Jr. Am. Med. Assoc., 1942, cxix, 632. CrossrefGoogle Scholar33. ROSENTHALHARRIS NW: Leukemia: its diagnosis and treatment, Jr. Am. Med. Assoc., 1935, civ, 702-706. CrossrefGoogle Scholar34. SCHIASSI F: Mielosi leucemica cronica clinicamente guarita dopo quasi 10 anni, Bull. d. sci. med., 1933, cv, 289. Google Scholar35. STURGIS CC: The Leukemias. A Textbook of Medicine, 1947, W. B. Saunders Company, Edited by Cecil, R. L., Ed. 7, Philadelphia, Pennsylvania. Google Scholar36. ULRICHPARKS HH: The relation between leukemia and tuberculosis, New England Jr. Med., 1940, ccxxii, 711-714. CrossrefGoogle Scholar37. WASHBURN AH: Chloroma—report of a case with recovery following roentgenotherapy, with a review of the literature, Am. Jr. Dis. Child., 1930, xxxix, 330-348. CrossrefGoogle Scholar38. WASHBURNCHRISTIE AHAV: Xanthoma or chloroma. Follow-up data on case of "chloroma" reported in 1930, Am. Jr. Dis. Child., 1942, lxiii, 335-345. CrossrefGoogle Scholar39. WHITBYCHRISTIE LEJM: Monocytic leukemia, Lancet, 1935, i, 80-82. CrossrefGoogle Scholar40. WIDMANN BP: Results of roentgen treatment of leukemia, Am. Jr. Roentgenol. and Rad. Therap., 1946, lv, 377-386. Google Scholar41. WINTROBEHASENBUSH MMLL: Chronic leukemia. The early phase of chronic leukemia, the results of treatment and the effects of complicating infections; a study of eighty-six adults, Arch. Int. Med., 1939, lxiv, 701-718. CrossrefGoogle Scholar42. WINTROBE MM: Clinical Hematology, 1942, Lea and Febiger, Philadelphia, Pennsylvania. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication October 16, 1948.This work was aided in part by the Henry Stevens Kiersted Memorial Fund for Medical Research.From the Radiation Laboratory, the Division of Medical Physics and the Division of Medicine, Donner Laboratory of Medical Physics, University of California. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byTerminal-Phase Chronic Myelogenous Leukemia: Approaches to TreatmentThe clinical management of leukemiaDie lymphatische Leuk�mieHOST-TUMOR ANTAGONISM. III. PROLONGED SURVIVAL OF CERTAIN PATIENTS WITH CANCER. 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