The Genetic Architecture of Depression in Individuals of East Asian Ancestry
Authors: Olga Giannakopoulou, Kuang Lin, Xiangrui Meng, Mei-Hsin Su, Po-Hsiu Kuo, Roseann E. Peterson, Swapnil Awasthi, Arden Moscati, Jonathan R. I. Coleman, Nick Bass, Iona Y. Millwood, Yiping Chen, Zhengming Chen, Hsi-Chung Chen, Mong-Liang Lu, Ming-Chyi Huang, Chun-Hsin Chen, Eli A. Stahl, Ruth J. F. Loos, Niamh Mullins, Robert J. Ursano, Ronald C. Kessler, Murray B. Stein, Srijan Sen, Laura J. Scott, Margit Burmeister, Yu Fang, Jess Tyrrell, Yunxuan Jiang, Chao Tian, Andrew M. McIntosh, Stephan Ripke, Erin C. Dunn, Kenneth S. Kendler, Robin G. Walters, Cathryn M. Lewis, Karoline Kuchenbaecker, Naomi R. Wray, Stephan Ripke, Manuel Mattheisen, Maciej Trzaskowski, Enda M. Byrne, Abdel Abdellaoui, Mark J. Adams, Esben Agerbo, Tracy M. Air, Till F. M. Andlauer, Silviu-Alin Bacanu, Marie Bækvad-Hansen, Aartjan T. F. Beekman, Tim B. Bigdeli, Elisabeth B. Binder, Julien Bryois, Henriette N. Buttenschøn, Jonas Bybjerg-Grauholm, Na Cai, Enrique Castelao, Jane Hvarregaard Christensen, Toni-Kim Clarke, Jonathan R. I. Coleman, Lucía Colodro-Conde, Hilary Coon, Baptiste Couvy-Duchesne, Nick Craddock, Gregory E. Crawford, Gail Davies, Ian J. Deary, Franziska Degenhardt, Eske M. Derks, Nese Direk, Conor V. Dolan, Erin C. Dunn, Thalia C. Eley, Valentina Escott-Price, Farnush Farhadi Hassan Kiadeh, Hilary K. Finucane, Jerome C. Foo, Andreas J. Forstner, Josef Frank, Héléna A. Gaspar, Michael Gill, Fernando S. Goes, Scott D. Gordon, Jakob Grove, Lynsey S. Hall, Christine Søholm Hansen, Thomas F. Hansen, Stefan Herms, Ian B. Hickie, Per Hoffmann, Georg Homuth, Carsten Horn, Jouke-Jan Hottenga, David M. Howard, David M. Hougaard, Marcus Ising, Rick Jansen, Ian Jones, Lisa A. Jones, Eric Jorgenson, James A. Knowles, Isaac S. Kohane, Julia Kraft, Warren W. Kretzschmar, Zoltán Kutalik, Yihan Li, Penelope A. Lind, Jurjen J. Luykx, Donald J. MacIntyre, Dean F. MacKinnon, Robert M. Maier, Wolfgang Maier, Jonathan Marchini, Hamdi Mbarek, Patrick McGrath, Peter McGuffin, Sarah E. Medland, Divya Mehta, Christel M. Middeldorp, Evelin Mihailov, Yuri Milaneschi, Lili Milani, Francis M. Mondimore, Grant W. Montgomery, Sara Mostafavi, Niamh Mullins, Matthias Nauck, Bernard Ng, Michel G. Nivard, Dale R. Nyholt, Paul F. O'Reilly, Hogni Oskarsson, Michael J. Owen, Jodie N. Painter, Carsten Bøcker Pedersen, Marianne Giørtz Pedersen, Roseann E. Peterson, Erik Pettersson, Wouter J. Peyrot, Giorgio Pistis, Danielle Posthuma, Jorge A. Quiroz, Per Qvist, John P. Rice, Brien P. Riley, Margarita Rivera, Saira Saeed Mirza, Robert Schoevers, Eva C. Schulte, Ling Shen, Jianxin Shi, Stanley I. Shyn, Engilbert Sigurdsson, Grant C. B. Sinnamon, Johannes H. Smit, Daniel J. Smith, Hreinn Stefansson, Stacy Steinberg, Fabian Streit, Jana Strohmaier, Katherine E. Tansey, Henning Teismann, Alexander Teumer, Wesley Thompson, Pippa A. Thompson, Thorgeir E. Thorgeirsson, Matthew Traylor, Jens Treutlein, Vassily Trubetskoy, André G. Uitterlinden, Daniel Umbricht, Sandra Van der Auwera, Albert M. van Hemert, Alexander Viktorin, Peter M. Visscher, Yunpeng Wang, Bradley T. Webb, Shantel Marie Weinsheimer, Jürgen Wellmann, Gonneke Willemsen, Stephanie H. Witt, Yang Wu, Hualin S. Xi, Jian Yang, Futao Zhang, Volker Arolt, Bernhard T Baune, Klaus Berger, Dorret I. Boomsma, Sven Cichon, Udo Dannlowski, EJC de Geus, J. Raymond DePaulo, Enrico Domenici, Katharina Domschke, Tõnu Esko, Hans J. Grabe, Steven P. Hamilton, Caroline Hayward, Andrew C. Heath, Kenneth S. Kendler, Stefan Kloiber, Glyn Lewis, Qingqin S. Li, Susanne Lucae, Pamela AF Madden, Patrik K. Magnusson, Nicholas G. Martin, Andrew M. McIntosh, Andres Metspalu, Ole Mors, Preben Bo Mortensen, Bertram Müller-Myhsok, Merete Nordentoft, Markus M. Nöthen, Michael C. O'Donovan, Sara A. Paciga, Nancy L. Pedersen, Brenda WJH Penninx, Roy H. Perlis, David J. Porteous, James B. Potash, Martin Preisig, Marcella Rietschel, Catherine Schaefer, Thomas G. Schulze, Jordan W. Smoller, Kari Stefansson, Henning Tiemeier, Rudolf Uher, Henry Völzke, Myrna M. Weissman, Thomas Werge, Cathryn M. Lewis, Douglas F. Levinson, Gerome Breen, Anders D. Børglum, Patrick F. Sullivan, Michelle Agee, Stella Aslibekyan, Adam Auton, Elizabeth Babalola, Robert K. Bell, Jessica Bielenberg, Katarzyna Bryc, Emily Bullis, Briana Cameron, Daniella Coker, Gabriel Cuellar Partida, Devika Dhamija, Sayantan Das, Sarah L. Elson, Teresa Filshtein, Kipper Fletez-Brant, Pierre Fontanillas, Will Freyman, Pooja M. Gandhi, Karl Heilbron, Barry Hicks, David A. Hinds, Karen E. Huber, Ethan M. Jewett, Yunxuan Jiang, Aaron Kleinman, Katelyn Kukar, Vanessa Lane, Keng-Han Lin, Maya Lowe, Marie K. Luff, Jennifer C. McCreight, Matthew H. McIntyre, Kimberly F. McManus, Steven J. Micheletti, Meghan E. Moreno, Joanna L. Mountain, Sahar V. Mozaffari, Priyanka Nandakumar, Elizabeth S. Noblin, Jared O'Connell, Aaron A. Petrakovitz, G. David Poznik, Morgan Schumacher, Anjali J. Shastri, Janie F. Shelton, Jingchunzi Shi, Suyash Shringarpure, Chao Tian, Vinh Tran, Joyce Y. Tung, Xin Wang, Wei Wang, Catherine H. Weldon, Peter Wilton, Daniel Avery, Derrick Bennett, Zheng Bian, Ruth Boxall, Fiona Bragg, Ka Hung Chan, Liang Chang, Yumei Chang, Biyun Chen, Jinyan Chen, Junshi Chen, Naying Chen, Ningyu Chen, Xiaofang Chen, Yiping Chen, Zhengming Chen, Liang Cheng, Johnathan Clarke, Robert Clarke, Rory Collins, Caixia Dong, Huaidong Du, Ranran Du, Zammy Fairhurst-Hunter, Lei Fan, Shixian Feng, Zhongxi Fu, Wei Gan, Ruqin Gao, Yulian Gao, Pengfei Ge, Simon Gilbert, Weiwei Gong, Qijun Gu, Yu Guo, Zhendong Guo, Ziyan Guo, Alex Hacker, Xiao Han, Parisa Hariri, Pan He, Tianyou He, Mike Hill, Michael Holmes, Can Hou, Wei Hou, Chen Hu, Ruying Hu, Ximin Hu, Yihe Hu, Hua Hua, Yujie Hua, Yuelong Huang, Pek Kei Im, Andri Iona, Qilian Jiang, Jianrong Jin, Maria Kakkoura, Quan Kang, Christiana Kartsonaki, Rene Kerosi, Ling Kong, Jian Lan, Garry Lancaster, Feifei Li, Huimei Li, Jianguo Li, Liming Li, Mingqiang Li, Shanpeng LI, Yanjie Li, Yilei Li, Zhongxiao Li, Kuang Lin, Lingli Lingli, Chao Liu, Depei Liu, Duo Liu, Fang Liu, Huilin Liu, Jiaqiu Liu, Jingchao Liu, Yongmei Liu, Yun Liu, Huajun Long, Yan Lu, Guojin Luo, Jun Lv, Silu Lv, Liangcai Ma, Enke Mao, John McDonnell, Fanwen Meng, Jinhuai Meng, Iona Millwood, Qunhua Nie, Feng Ning, Dongxia Pan, Rong Pan, Zengchang Pang, Pei Pei, Richard Peto, Alfred Pozarickij, Yijian Qian, Yulu Qin, Chan Qu, Xiaolan Ren, Paul Ryder, Sam Sansome, Dan Schmidt, Paul Sherliker, Rajani Sohoni, Becky Stevens, Jian Su, Huarong Sun, Qiang Sun, Xiaohui Sun, Aiyu Tang, Zhenzhu Tang, Ran Tao, Xiaocao Tian, Iain Turnbull, Robin Walters, Meng Wan, Chunmei Wang, Chen Wang, Hao Wang, Junzheng Wang, Lin Wang, Ping Wang, Tao Wang, Shaojie Wang, Sisi Wang, Xiaohuan Wang, Liuping Wei, Min Weng, Neil Wright, Ming Wu, Xianping Wu, Shukuan Wu, Kaixu Xie, Qiaohua Xu, Qinai Xu, Xin Xu, Shichun Yan, Ling Yang, Xiaoming Yang, Jie Yang, Pang Yao, Li Yin, Bo Yu, Canqing Yu, Min Yu, Yaoming Zhai, Hao Zhang, Hui Zhang, Jun Zhang, Libo Zhang, Ningmei Zhang, Xi Zhang, Xiaoyi Zhang, Xukui Zhang, Xunfu Zhong, Ding Zhang Zhou, Gang Zhou, Jinyi Zhou, Liyuan Zhou, Weiwei Zhou, Xue Zhou, Yonglin Zhou, Mingyuan Zou
Journal: JAMA Psychiatry (2021)

Most previous genome-wide association studies (GWAS) of depression have used data from individuals of European descent. This limits the understanding of the underlying biology of depression and raises questions about the transferability of findings between populations.