tbuckley/cabot-search huggingface dataset:
Severe Infections in Patients with Chronic Lymphocytic Leukemia Treated with (Immuno-)Chemotherapy: A Pooled Analysis of Gcllsg Trials
Authors: Othman Al-Sawaf, Can Zhang, Sandra Robrecht, Anna-Maria Fink, Paula Cramer, Carmen D. Herling, Julia Von Tresckow, Elisabeth Lange, Sebastian Böttcher, Michael G. Kiehl, Martin Dreyling, Ulrich Jaeger, Michael Gregor, Ursula Vehling-Kaiser, Matthias Ritgen, Jan Dürig, Eugen Tausch, Stephan Stilgenbauer, Clemens-Martin Wendtner, Kirsten Fischer, Valentin Goede, Michael Hallek, Barbara Eichhorst, Petra Langerbeins
Journal: Blood (2020)
Vaccination of Hematopoietic Stem Cell (HCT) Donors with Triplex, a Novel Cytomegalovirus Vaccine: Safety, Feasibility and Adoptive Transfer of Protective CMV-Specific T Cells in HCT Recipients
Authors: Ryotaro Nakamura, Corinna La Rosa, Ibrahim Aldoss, Qiao Zhou, Chetan Raj Lingaraju, Joy Martinez, Teodora Kaltcheva, Don J. Diamond
Journal: Blood (2020)
Factors Influencing Time from Initial Presentation to Start of Plasma Exchange (PEX) in Patients with Acute Thrombotic Thrombocytopenic Purpura (TTP)
Authors: Rory McCulloch, Tom Bull, Phillip LR Nicolson, Rebecca J Shaw, Zara Sayar, Alexander Langridge, Michala Pettitt, Rita Perry, David Tucker, Marie Scully, HaemSTAR Collaborators. (# joint first authors)
Journal: Blood (2020)
Multi-Site Randomized Trial of Integrated Palliative and Oncology Care for Patients with Acute Myeloid Leukemia (AML)
Authors: Areej El-Jawahri, Thomas W. Leblanc, Alison R. Kavanaugh, Jason A. Webb, Vicki Jackson, Toby Campbell, Nina R. O'Connor, Selina M. Luger, Ellin Gafford, Jillian Gustin, Bhavana Bhatnagar, Amir T. Fathi, Gabriela S. Hobbs, Showly Nicholson, Debra Davis, Jennifer S. Temel
Journal: Blood (2020)
Impact of Letermovir Prophylaxis on Voriconazole Exposure in Allogeneic Hematopoietic Cell Transplant Recipients
Authors: Issam S. Hamadeh, Michael R. Grunwald, Allison Martin, Jai N. Patel, Alexandra Shillingburg, Ekaterina Kachur, Allene COOK, Allison Karabinos, Jing Ai, Thomas G. Knight, Brittany K. Ragon, Aleksander L. Chojecki, Nilay A. Shah, Srinivasa R. Sanikommu, Belinda R Avalos, Edward A Copelan, Zainab Shahid
Journal: Blood (2020)
Central Nervous System Cancers, Version 3.2020, NCCN Clinical Practice Guidelines in Oncology
Authors: Louis Burt Nabors, Jana Portnow, Manmeet Ahluwalia, Joachim Baehring, Henry Brem, Steven Brem, Nicholas Butowski, Jian L. Campian, Stephen W. Clark, Andrew J. Fabiano, Peter Forsyth, Jona Hattangadi-Gluth, Matthias Holdhoff, Craig Horbinski, Larry Junck, Thomas Kaley, Priya Kumthekar, Jay S. Loeffler, Maciej M. Mrugala, Seema Nagpal, Manjari Pandey, Ian Parney, Katherine Peters, Vinay K. Puduvalli, Ian Robins, Jason Rockhill, Chad Rusthoven, Nicole Shonka, Dennis C. Shrieve, Lode J. Swinnen, Stephanie Weiss, Patrick Yung Wen, Nicole E. Willmarth, Mary Anne Bergman, Susan D. Darlow
Journal: Journal of the National Comprehensive Cancer Network (2020)

The NCCN Guidelines for Central Nervous System (CNS) Cancers focus on management of adult CNS cancers ranging from noninvasive and surgically curable pilocytic astrocytomas to metastatic brain disease. The involvement of an interdisciplinary team, including neurosurgeons, radiation therapists, oncologists, neurologists, and neuroradiologists, is a key factor in the appropriate management of CNS cancers. Integrated histopathologic and molecular characterization of brain tumors such as gliomas should be standard practice. This article describes NCCN Guidelines recommendations for WHO grade I, II, III, and IV gliomas. Treatment of brain metastases, the most common intracranial tumors in adults, is also described.
Minimal Residual Disease Assessment Is an Independent Prognostic Factor in Splenic Marginal Zone Lymphoma
Authors: Ryu Lv, Yi Wang, Tingyu Wang, Xiong Wenjie, Huijun Wang, Yuting Yan, Qi Wang, Wei Liu, Gang An, Wenyang Huang, Weiwei Sui, Yan Xu, Zhen Yu, Dehui Zou, Jianxiang Wang, Lugui Qiu, Shuhua Yi
Journal: Blood (2020)
Ibrutinib Plus Venetoclax in Patients With Relapsed/Refractory Mantle Cell Lymphoma: Results From the Safety Run-In Period of the Phase 3 Sympatico Study
Authors: Constantine S. Tam, Radhakrishnan Ramchandren, Robert Chen, Lionel Karlin, Geoffrey Chong, Wojciech Jurczak, Ka Lung Wu, Mark Bishton, Graham P. Collins, Paul Eliadis, Frédéric Peyrade, Edith Szafer-Glusman, Yihua Lee, Karl Eckert, Jutta K. Neuenburg, Michael Wang
Journal: Blood (2020)
Predicting Long-Term Absence of Coronary Artery Calcium in Metabolic Syndrome and Diabetes
Authors: Alexander C. Razavi, Nathan Wong, Matthew Budoff, Lydia A. Bazzano, Tanika N. Kelly, Jiang He, Camilo Fernandez, Joao Lima, Joseph F. Polak, Morgana Mongraw-Chaffin, Chris deFilippi, Moyses Szklo, Alain G. Bertoni, Roger S. Blumenthal, Michael J. Blaha, Seamus P. Whelton
Journal: JACC. Cardiovascular imaging (2020)
Phase I Study of Adoptive Immunotherapy with HA-1-Specific CD8+ and CD4+ Memory T Cells for Children and Adults with Relapsed Acute Leukemia after Allogeneic Hematopoietic Stem Cell Transplantation (HCT): Trial in Progress
Authors: Elizabeth F Krakow, Corinne Summers, Ann Dahlberg, Merav Bar, Melinda Ann Biernacki, Tanya Cunningham, Nicole Vartanian, Megan Hickner, Colette Chaney, Tsadik Habtetsion, Kyle Woodward, Robson Dossa, Michelle Brault, Marie Bleakley
Journal: Blood (2020)
Safety and Antitumor Effects of CD19-Specific Autologous Chimeric Antigen Receptor-Modified T (CAR-T) Cells Expressing the Inducible Caspase 9 Safety Switch (iC9-CAR19 T Cells) in Adult Acute Lymphoblastic Leukemia (ALL)
Authors: Matthew C Foster, Philip A. Roehrs, George E Hucks, Natalie S Grover, Paul M. Armistead, Katarzyna Jamieson, Faith Brianne Buchanan, J. Kaitlin C Morrison, Spencer Laing, Catherine Joyce Arago Cheng, Jonathan S. Serody, Gianpietro Dotti, Barbara Savoldo
Journal: Blood (2020)
TMEM16A/ANO1 calcium-activated chloride channel as a novel target for the treatment of human respiratory syncytial virus infection
Authors: Hayley Pearson, Eleanor J A A Todd, Mareike Ahrends, Samantha E Hover, Adrian Whitehouse, Martin Stacey, Jonathan D Lippiat, Ludwig Wilkens, Hans-Gerd Fieguth, Olga Danov, Christina Hesse, John N Barr, Jamel Mankouri
Journal: Thorax (2020)

Introduction Human respiratory syncytial virus (HRSV) is a common cause of respiratory tract infections (RTIs) globally and is one of the most fatal infectious diseases for infants in developing countries. Of those infected, 25%–40% aged ≤1 year develop severe lower RTIs leading to pneumonia and bronchiolitis, with ~10% requiring hospitalisation. Evidence also suggests that HRSV infection early in life is a major cause of adult asthma. There is no HRSV vaccine, and the only clinically approved treatment is immunoprophylaxis that is expensive and only moderately effective. New anti-HRSV therapeutic strategies are therefore urgently required. Methods It is now established that viruses require cellular ion channel functionality to infect cells. Here, we infected human lung epithelial cell lines and ex vivo human lung slices with HRSV in the presence of a defined panel of chloride (Cl − ) channel modulators to investigate their role during the HRSV life-cycle. Results We demonstrate the requirement for TMEM16A, a calcium-activated Cl − channel, for HRSV infection. Time-of-addition assays revealed that the TMEM16A blockers inhibit HRSV at a postentry stage of the virus life-cycle, showing activity as a postexposure prophylaxis. Another important negative-sense RNA respiratory pathogen influenza virus was also inhibited by the TMEM16A-specific inhibitor T16Ainh-A01. Discussion These findings reveal TMEM16A as an exciting target for future host-directed antiviral therapeutics.
Comparison of Outcomes and Quality-of-Life Measures Following Haploidentical Vs. Matched Related/Unrelated Donor Allogeneic Hematopoietic Cell Transplantation
Authors: Sanghee Hong, Lisa Rybicki, Linda McLellan, Jane Dabney, Aaron T. Gerds, Seth J Rotz, Matt Kalaycio, Rabi Hanna, Betty K. Hamilton, Navneet S. Majhail, Ronald Sobecks
Journal: Blood (2020)
Pentraxin 3: Potential prognostic role in SARS-CoV-2 patients admitted to the emergency department
Authors: Annalisa Schirinzi, Francesco Pesce, Riccardo Laterza, Maria Gabriella D'Alise, Roberto Lovero, Antonietta Fontana, Renato Contino, Francesca Di Serio
Journal: Journal of Infection (2020)
Treatment Duration, Symptom Resolution, and Survival in Defibrotide-Treated Patients with Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome after Hematopoietic Cell Transplantation: Analysis of a Multinational, Prospective, Observational Registry Study
Authors: Franco Locatelli, Maura Faraci, Ibrahim Yakoub-Agha, Stephane Girault, Kate Wheeler, Robert J. Ryan, Raj Hanvesakul, Mohamad Mohty
Journal: Blood (2020)
Expansion of murine and human olfactory epithelium/mucosa colonies and generation of mature olfactory sensory neurons under chemically defined conditions
Authors: Wenwen Ren, Li Wang, Xiujuan Zhang, Xiaoyu Feng, Liujing Zhuang, Nan Jiang, Rui Xu, Xuewen Li, Ping Wang, Xicai Sun, Hongmeng Yu, Yiqun Yu
Journal: Theranostics (2020)

Olfactory dysfunctions, including hyposmia and anosmia, affect ~100 million people around the world and the underlying causes are not fully understood. Degeneration of olfactory sensory neurons and incapacity of globose basal cells to generate olfactory sensory neurons are found in elder people and patients with smell disorders. Thus, olfactory stem cell may function as a promising tool to replace inactivated globose basal cells and to generate sensory neurons. Methods: We established clonal expansion of cells from the murine olfactory epithelium as well as colony growth from human olfactory mucosa using Matrigel-based three-dimensional system. These colonies were characterized by immunostaining against olfactory epithelium cellular markers and by calcium imaging of responses to odors. Chemical addition was optimized to promote Lgr5 expression, colony growth and sensory neuron generation, tested by quantitative PCR and immunostaining against progenitor and neuronal markers. The differential transcriptomes in multiple signaling pathways between colonies under different base media and chemical cocktails were determined by RNA-Seq. Results: In defined culture media, we found that VPA and CHIR99021 induced the highest Lgr5 expression level, while LY411575 resulted in the most abundant yield of OMP+ mature sensory neurons in murine colonies. Different base culture media with drug cocktails led to apparent morphological alteration from filled to cystic appearance, accompanied with massive transcriptional changes in multiple signaling pathways. Generation of sensory neurons in human colonies was affected through TGF-β signaling, while Lgr5 expression and cell proliferation was regulated by VPA. Conclusion: Our findings suggest that targeting expansion of olfactory epithelium/mucosa colonies in vitro potentially results in discovery of new source to cell replacement-based therapy against smell loss.
THU0403 THE EFFECT OF SPINAL STABILIZATION EXERCISES ON SPINAL CURVES DIAGNOSED WITH ANKYLOSING SPONDYLITIS
Authors: Y. Tunç
Journal: Annals of the Rheumatic Diseases (2020)

Background: Postural deformities can cause changes in spinal curvatures patients with ankylosing spondylitis. In these patients, preventive and therapeutic approaches are needed for spinal deformities (1). Positive effects of the spinal stabilization exercises are manifested in reducing pain, maintaining mobility, improving posture, increasing aerobic capacity and improving quality of life (2). Objectives: The aim of this study is to investigate the effect of stabilization exercises on spinal curvatures in s ankylosing spondylitis patients. Methods: Twenty-eight ankylosing spondylitis patients (25 females, 3 males) with a mean age of 30.87 ± 9.13 years were included in the stabilization exercises program. The patients performed spinal stabilization exercises two days a week for six weeks. Stabilization training includes training of deep muscles providing diaphragmatic breathing, neutral spine position control training and local motor control, and motor control training of global muscles, dynamic stabilization exercises and strengthening training. Thoracic kyphosis and lumbar lordosis curvature of patients in an upright position were evaluated with Spinal Mouse (SM) device before and after therapy program. The SM device is a reliable, valid, safe, quick method that can be used in the clinics and researches of the adults with no side effects. Results: At the end of 6 weeks of treatment, there was a decrease in the total curvature degree of the thoracic vertebrae in the sagittal axis ( p=0.026 ). No significant difference was found in the lumbal region (p= 0.109). Table 1. Differences of Total Curve Degrees Pre-Exercises Program Mean ± SD Post-Exercises Program Mean ± SD z p Thoracal Total Curve Degrees 43.50±8.11 42.57±7.70 -2.232 *0.026 Lumbal Total Curve Degrees -26.42±8.46 -23.77±7.15 -1.604 0.109 *p&lt;0.05, SD: Standart Deviation Conclusion: Stabilization exercises are effective in reducing thoracic kyphosis in patients with ankylosing spondylitis patients. The use of these exercises in treatment programs will contribute significantly to improving spinal alignment and preventing postural deformities. References: [1]Grazio, S., Grubišić, F., &amp; Brnić, V. (2019). Rehabilitation of patients with spondyloarthritis: a narrative review. Medicinski Glasnik , 16 (2). [2]Gunay, S. M., Keser, I., &amp; Bicer, Z. T. (2018). The effects of balance and postural stability exercises on spa based rehabilitation programme in patients with ankylosing spondylitis. Journal of back and musculoskeletal rehabilitation , 31 (2), 337-346. Disclosure of Interests: : None declared
AB0853 IMPACT OF ULTRASONOGRAPHY‑DETECTED PES ANSERINE BURSITIS ON PAIN ANDFUNCTION IN PATIENTS WITH PRIMARY KNEE OSTEOARTHRITIS
Authors: M. A. Mortada, Y. A. Amer, R. Zaghlol
Journal: Annals of the Rheumatic Diseases (2020)

Background: Pes anserine bursitis (PAB) is one of the most common causes of knee pain. Hence, this study aimed to compare the pain and function among all primary knee osteoarthritis (KOA) patients with or without ultrasonic-detected PAB and the associated clinical and radiological findings. Objectives: To compare pain, function, and clinical and radiological findings among primary KOA patients with or without ultrasonography-detected PAB. Methods: A single-center cross-sectional study was conducted on 245 patients with primary KOA. Patients with more symptomatic knee examined by musculoskeletal ultrasound (MSUS), then according to the presence or abscence of PAB, the patients were categorized into two groups. To differentiate between grades of inflammation of PAB on ultrasonography, the authors developed a semi-quantitative scale (0–2) as follows: Grade 0, normal hyperechoic picture of pes anserine tendons without tendonitis or bursitis; Grade 1, mild hypoechogenicity and/ or mild swelling or mild loss of fibrillar pattern of the pes anserine tendon and/or mild anechoic effusion related to the tendons; and Grade 2, marked hypoechogenicity and/ or large swelling or marked loss of the pes anserine tendon and/or marked anechoic effusion related to the tendons.. Radiological grades of Kellgren–Lawrence were recorded. Pain and functional status was assessed by visual analog scale (VAS), Health Assessment Questionnaire-II (HAQ-II), and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Results: A total of 110 (44.9%) patients were diagnosed with PAB where 91 (82.7%) of them had Grade 1 and only 19 (17.3%) had Grade 2. The presence of PAB was statistically significant related ( P &lt; 0.05*) with age, VAS, HAQ-II, WOMAC subscales, synovitis, and radiographic Grades 3 and 4. However, there was no statistically significant difference ( P ≥ 0.05) between KOA patients without PAB and KOA patients with PAB, regarding sex, body mass index, baker cyst, and effusion. Conclusion: The presence of PAB on MUS is associated with increased pain and disability in KOA. MSUS should be more widely used to establish the association between PAB and symptom severity and disability among KOA patients. References: None Disclosure of Interests: None declared
<i>ZRSR2</i> Mutation Induced Minor Intron Retention Drives MDS and Diverse Cancer Predisposition Via Aberrant Splicing of <i>LZTR1</i>
Authors: Daichi Inoue, Jacob T. Polaski, Justin Taylor, Pau Castel, Sisi Chen, Susumu Kobayashi, Simon J. Hogg, Yasutaka Hayashi, Jose Mario Bello Pineda, Alexander V Penson, Ettaib El Marabti, Caroline Erickson, Miki Fukumoto, Hiromi Yamazaki, Chie Fukui, Sydney X. Lu, Benjamin H. Durham, Bo Liu, Sanjoy Mehta, Daniel Zakheim, Ralph Garippa, Guo-Liang Chew, Frank McCormick, Robert K. Bradley, Omar Abdel-Wahab
Journal: Blood (2020)
Pragmatic trials with prespecified subgroups: what oncologists can learn from COVID-19
Authors: Rahul Banerjee, Vinay Prasad
Journal: Nature Reviews Clinical Oncology (2020)

Randomized controlled trials designed to test cancer therapies often fail to clarify effectiveness in real-world settings. Herein, we explore lessons for trial development in oncology that can be learnt from the large-cohort, pragmatic RECOVERY trial involving patients hospitalized with COVID-19.
David Oliver: Detoxifying DNACPR decisions
Authors: David Oliver
Journal: BMJ (2020)

Could healthcare practitioners do more to demystify and detoxify the public conversation on "Do Not Attempt Cardiopulmonary Resuscitation" (DNACPR) decisions?Even before covid-19, DNACPR orders featured in many a misunderstanding or formal complaint.The pandemic response has made these orders more contentious, and the Care Quality Commission recently announced that it would review how DNACPR decisions had been used during the pandemic.
Characteristics and Outcomes of Newly Diagnosed Acute Myeloid Leukemia Patients Receiving Venetoclax Combinations Vs Other Therapies: Results from the AML Real World Evidence (ARC) Initiative
Authors: Daniel A. Pollyea, Maximilian Stahl, Chetasi Talati, Hannah Asghari, Catherine Lai, Sameem Abedin, Joshua F. Zeidner, Benyam Muluneh, Marin Xavier, Wesleigh Edwards, Ofir Wolach, Yakir Moshe, David Lavie, Tsila Zuckerman, Michelle Choi, Cat N. Bui, Anders Erik Svensson, Steve Kye, Rebecca Burne, Annie Guerin, Esprit Ma, Melissa Montez, Aaron D Goldberg
Journal: Blood (2020)
Comparative Effectiveness of Pegcetacoplan Versus Ravulizumab in Patients with Paroxysmal Nocturnal Hemoglobinuria Previously Treated with Eculizumab: A Matching-Adjusted Indirect Comparison
Authors: Rachel Y Bhak, Nikita Mody-Patel, Scott B. Baver, Colin Kunzweiler, Christopher Yee, Sanjana Sundaresan, Natalia Swartz, Mei Sheng Duh, Sangeeta Krishnan, Sujata P. Sarda
Journal: Blood (2020)
Genomic Profiling Reveals Molecular Heterogeneity in Patients with Richter's Syndrome (RS) and Progressive Chronic Lymphocytic Leukemia (CLL)
Authors: Shulan Tian, Hanyin Wang, Timothy G. Call, Eric W. Klee, Minetta C. Liu, Erik Jessen, Sameer A. Parikh, Yucai Wang, Saad S. Kenderian, Jose F. Leis, Min Shi, Eli Muchtar, Daniel L. Van Dyke, Amber B. Koehler, Neil E. Kay, Susan L. Slager, Esteban Braggio, Huihuang Yan, Wei Ding
Journal: Blood (2020)
Abstract 264: Upstream and Downstream Regulators of Lysophosphatidic Acid Receptor 4 are Critical for Cardiac Differentiation and Repair
Authors: Hyun-jai Cho, Jin-Woo Lee, Choon-Soo Lee, Hyo-Soo Kim
Journal: Circulation Research (2020)

The therapeutic application of cell therapy to repair the damaged heart requires a comprehensive understanding of the process of cardiac differentiation of stem cells. We discovered a cardiac-specific marker, lysophosphatidic acid receptor 4 (LPAR4), which is G protein-coupled receptor (GPCR) and demonstrated its functional significance during cardiac differentiation. We screened GPCR expressing on mouse cardiac progenitor cells at differentiation day 3 compared to mouse undifferentiated pluripotent stem cells (PSCs). Among candidates, we identified LPAR4. We have found that in both mouse and human PSCs, LPAR4 has a transient expression pattern during cardiac differentiation. During in vitro differentiation of mouse and human PSCs toward cardiomyocytes, LPAR4 expression peaked for 3-5 days and then and declined immediately. Treatment with ODP (LPAR4 specific agonist) followed by p38MAPK blocker (SB203580) in the cardiac differentiation protocol significantly increased cardiac differentiation efficiency. Then we performed RNA sequencing to find transcription factors that regulate LPAR4. We screened 2-fold up-regulated transcription factors that related to cardiac differentiation during human iPSCs toward cardiomyocytes. The expression of LPAR4 is regulated by SOX17 expression, demonstrating that SOX17 is an upstream regulator of LPAR4. During cardiac differentiation, when knocking down SOX17 by siRNA, the expression of LPAR4 decreased as the expression of SOX17 mRNA decreased, resulting in no progression of cardiac differentiation. Besides, cardiac differentiation did not progress when SOX17 was overexpressed. SOX17 plays a role early in cardiac differentiation and that the expression should be reduced. However, it is assumed that sox17 lentivirus was gene-integrated and continued expression without decreasing expression. SOX17 overexpression needs further study. In conclusion, we demonstrated that LPAR4 is a novel cardiac progenitor cell marker and modulation of the upstream and downstream regulators shown functional significance during cardiac differentiation. Furthermore, our findings provide new insight into cell-free cardiac repair by the modulation of LPAR4 positive cells in the heart. Funding Source: This study was supported by "Strategic Center of Cell and Bio Therapy for Heart, Diabetes &amp; Cancer" (HI17C2085) through the Korea Health Industry Development Institute, funded by the Ministry of Health &amp; Welfare, Republic of Korea.
Free Asparagine or Die: Cancer Cells Require Proteasomal Protein Breakdown to Survive Asparagine Depletion
Authors: Kristian Davidsen, Lucas B. Sullivan
Journal: Cancer Discovery (2020)

The chemotherapeutic enzyme asparaginase depletes systemic asparagine to kill cancers; however, its efficacy thus far is limited to a subset of leukemias. Hinze and colleagues identify that inhibiting proteasomal release of asparagine can sensitize colorectal cancers to asparagine depletion, providing a potential avenue to repurpose asparaginase for treatment of solid tumors.See related article by Hinze et al., p. 1690.
Vaccination Response after Autologous Stem Cell Transplantation
Authors: Onder Alpdogan, Jennifer Hong, Thomas R. Klumpp, Abdullateef O Abdulkareem, Adam F. Binder, Matthew Carabasi, Joanne Filicko-O'Hara, Dolores Grosso, Margaret Kasner, Ubaldo Martinez-Outschoorn, Neil Palmisiano, Lindsay Wilde, Pierluigi Porcu, Usama Gergis, John L. Wagner, Neal Flomenberg
Journal: Blood (2020)
HORIZON (OP-106): Melflufen Plus Dexamethasone (dex) in Patients (pts) with Relapsed/Refractory Multiple Myeloma (RRMM)-Analysis of Adverse Events Related to Hospitalizations
Authors: Omar Nadeem, Paul G. Richardson, María-Victoria Mateos, Albert Oriol, Alessandra Larocca, Joan Blade Creixenti, Paula Rodríguez-Otero, Xavier Leleu, Maxim Norkin, John W. Hiemenz, Hani Hassoun, Cyrille Touzeau, Adrián Alegre Amor, Agne Paner, Christopher Maisel, Amitabha Mazumder, Anastasios Raptis, Noemí Puig, Anna Sandberg, Ivonne Pelaez, Christian Jaques, Marie Orre, Michele Cavo
Journal: Blood (2020)
Efficacy and Safety of Sabatolimab (MBG453) in Combination with Hypomethylating Agents (HMAs) in Patients with Acute Myeloid Leukemia (AML) and High-Risk Myelodysplastic Syndrome (HR-MDS): Updated Results from a Phase 1b Study
Authors: Andrew M. Brunner, Jordi Esteve, Kimmo Porkka, Steve Knapper, Norbert Vey, Sebastian Scholl, Guillermo Garcia-Manero, Martin Wermke, Jeroen Janssen, Elie Traer, Sun Loo, Rupa Narayan, Natalia Tovar, Mika Kontro, Oliver Ottmann, Purushotham Naidu, Sema Kurtulus, Jessica Makofske, Serena Liao, Anisa Mohammed, Catherine A. Sabatos-Peyton, Mikael L. Rinne, Uma Borate, Andrew H. Wei
Journal: Blood (2020)