tbuckley/cabot-search huggingface dataset:
Covid-19: Countries rally to support India through “storm that has shaken the nation”
Authors: Jacqui Wise
Journal: BMJ (2021)

Covid-19: Countries rally to support India through "storm that has shaken the nation" Jacqui WiseCountries around the world have pledged to help India as the country continues to see an exponential rise in covid-19 cases and deaths, with hospitals running out of oxygen, drugs, and beds. 6BMA. UK support for countries experiencing worsening covid-19 crisis.
Locally Adaptive Inversions Modulate Genetic Variation at Different Geographic Scales in a Seaweed Fly
Authors: Claire Mérot, Emma L Berdan, Hugo Cayuela, Haig Djambazian, Anne-Laure Ferchaud, Martin Laporte, Eric Normandeau, Jiannis Ragoussis, Maren Wellenreuther, Louis Bernatchez
Journal: Molecular Biology and Evolution (2021)

Across a species range, multiple sources of environmental heterogeneity, at both small and large scales, create complex landscapes of selection, which may challenge adaptation, particularly when gene flow is high. One key to multidimensional adaptation may reside in the heterogeneity of recombination along the genome. Structural variants, like chromosomal inversions, reduce recombination, increasing linkage disequilibrium among loci at a potentially massive scale. In this study, we examined how chromosomal inversions shape genetic variation across a species range and ask how their contribution to adaptation in the face of gene flow varies across geographic scales. We sampled the seaweed fly Coelopa frigida along a bioclimatic gradient stretching across 10° of latitude, a salinity gradient, and a range of heterogeneous, patchy habitats. We generated a chromosome-level genome assembly to analyze 1,446 low-coverage whole genomes collected along those gradients. We found several large nonrecombining genomic regions, including putative inversions. In contrast to the collinear regions, inversions and low-recombining regions differentiated populations more strongly, either along an ecogeographic cline or at a fine-grained scale. These genomic regions were associated with environmental factors and adaptive phenotypes, albeit with contrasting patterns. Altogether, our results highlight the importance of recombination in shaping adaptation to environmental heterogeneity at local and large scales.
HEMODYNAMIC PROFILES OF SHOCK IN CRITICALLY ILL COVID PATIENTS
Authors: Steven M. Hollenberg, Lucy Safi, Joseph Parrillo, Matthew Fata, Noha Gayed, Taya Glotzer, Ronaldo Go, Elli Gourna-Paleoudis, David Landers, Sameer Jamal, Brent Klinkhammer, Neel Shah, Roshan Shah, Jana Tancredi, Zoltan Turi
Journal: Journal of the American College of Cardiology (2021)
AORTIC STENOSIS BUT NOT MITRAL REGURGITATION INCREASES MORTALITY IN CARDIAC AMYLOIDOSIS PATIENTS
Authors: Adebayo Atanda, Olajide Buhari, Omowunmi Adedeji, Adeniyi Ajenifuja, Lily Dastmalchi, Padma Shenoy, Olakunle Akinboboye, Gurusher Panjrath, Joseph Krepp
Journal: Journal of the American College of Cardiology (2021)
ASSOCIATION OF LIPOPROTEIN SUBFRACTIONS WITH PRESENCE AND SEVERITY OF CORONARY ARTERY DISEASE IN STATIN-NAÏVE PATIENTS REFERRED FOR CORONARY ANGIOGRAPHY
Authors: Lusana Ahsan, Wen Zheng, Gurleen Kaur, Anusri Kadakuntla, Alan Remaley, Maureen Sampson, Paul Feustel, Anthony Nappi, Sulagna Mookherjee, Radmila Lyubarova
Journal: Journal of the American College of Cardiology (2021)
Sterile abscesses possibly stem from acantholytic folliculitis in comedonal Darier disease: a case report
Authors: T. Komatsu‐Fujii, T. Murata, E. Adachi, Y. Kaku, T. Wada, N. Nakagawa, S. Kosugi, T. Uehara, K. Kosaki, T. Kataoka, G. Egawa, T. Dainichi, K. Kabashima
Journal: British Journal of Dermatology (2021)
THE NEGLECTED POPULATION OF STEMI WITHOUT STANDARD MODIFIABLE CARDIOVASCULAR RISK FACTORS. INSIGHTS FROM A PROSPECTIVE SINGLE CENTRE STEMI REGISTRY
Authors: Justin Paul Gnanaraj, Mohamed Iliyas, Suriyakanth Sethupathy, Siva Subramaniyam Saravanan, Sijoy Kurian, Sandeep Srinivas, Karthikaa Saminathan, Sabarish Sankaran, Anurag Polavarapu, Nageswaran Piskala Mohandoss, G. Ravishankar, Thiyagarajan Bharath, G. Dharmaraj, Salai Sudhan Prabhu
Journal: Journal of the American College of Cardiology (2021)
BASELINE CLINICAL PROFILE OF CHRONIC HEART FAILURE IN NIGERIA: RESULT OF A NATIONAL REGISTRY
Authors: Okechukwu Samuel Ogah, Hadiza Saidu, Kamilu Karaye, Rasaq Adebayo, Amam Mbakwem, Umar Gati Adamu, Saheed O. Adebayo, Abiodun M. Adeoye, Akinyemi Aje, Adewole A. Adebiyi, Taiwo Sogade, Mahmoud Sani
Journal: Journal of the American College of Cardiology (2021)
Biosynthetic scaffolds for partial meniscal loss: A systematic review from animal models to clinical practice
Authors: F. Veronesi, B. Di Matteo, N.D. Vitale, G. Filardo, A. Visani, E. Kon, M. Fini
Journal: Bioactive Materials (2021)

Acute or degenerative meniscus tears are the most common knee lesions. Meniscectomy provides symptomatic relief and functional recovery only in the short- to mid-term follow-up but significantly increases the risk of osteoarthritis. For this reason, preserving the meniscus is key, although it remains a challenge. Allograft transplants present many disadvantages, so during the last 20 years preclinical and clinical research focused on developing and investigating meniscal scaffolds. The aim of this systematic review was to collect and evaluate all the available evidence on biosynthetic scaffolds for meniscus regeneration both in vivo and in clinical studies. Three databases were searched: 46 in vivo preclinical studies and 30 clinical ones were found. Sixteen natural, 15 synthetic, and 15 hybrid scaffolds were studied in vivo. Among them, only 2 were translated into clinic: the Collagen Meniscus Implant, used in 11 studies, and the polyurethane-based scaffold Actifit®, applied in 19 studies. Although positive outcomes were described in the short- to mid-term, the number of concurrent procedures and the lack of randomized trials are the major limitations of the available clinical literature. Few in vivo studies also combined the use of cells or growth factors, but these augmentation strategies have not been applied in the clinical practice yet. Current solutions offer a significant but incomplete clinical improvement, and the regeneration potential is still unsatisfactory. Building upon the overall positive results of these "old" technologies to address partial meniscal loss, further innovation is urgently needed in this field to provide patients better joint sparing treatment options.
Medical Records-Based Genetic Studies of the Complement System
Authors: Atlas Khan, Ning Shang, Lynn Petukhova, Jun Zhang, Yufeng Shen, Scott J. Hebbring, Halima Moncrieffe, Leah C. Kottyan, Bahram Namjou-Khales, Rachel Knevel, Soumya Raychaudhuri, Elizabeth W. Karlson, John B. Harley, Ian B. Stanaway, David Crosslin, Joshua C. Denny, Mitchell S.V. Elkind, Ali G. Gharavi, George Hripcsak, Chunhua Weng, Krzysztof Kiryluk
Journal: Journal of the American Society of Nephrology (2021)

Genetic variants in complement genes have been associated with a wide range of human disease states, but well-powered genetic association studies of complement activation have not been performed in large multiethnic cohorts.
Pityriasis rosea‐like eruption after Pfizer–BioNTech COVID‐19 vaccination
Authors: A.M. Carballido Vázquez, B. Morgado
Journal: British Journal of Dermatology (2021)

A 35-year-old male presented with an extremely itchy exanthem after Pfizer-BioNTech COVID-19 vaccination. 1 A single oval erythematous lesion appeared on the thigh after the first dose (a) and progressed insidiously to a papulosquamous rash on the trunk and proximal extremities (b).After the second dose, it notably flared up (c).Serological evaluation for human herpesvirus reactivation was negative.Pityriasis rosealike eruption was diagnosed. 2Antihistamines and topical betamethasone were initiated, with clinical improvement after 2 weeks.Considering that immunization programmes are being conducted worldwide, it is important to increase awareness within the medical community, so that appropriate management be provided.
循環器病の診断と治療に関するガイドライン(2004-2005年度合同研究班報告)心臓血管疾患における遺伝学的検査と遺伝カウンセリングに関するガイドライン
Authors: 中澤誠, 青見茂之, 梅村敏, 奥山虎之, 鎌谷直之, 小杉眞司, 斎藤加代子, 城尾邦隆, 永井良三, 平原史樹, 福嶋義光, 松岡瑠美子, 松田一郎, 松森昭, 山岸敬幸, 石上友章, 今井靖, 佐地勉, 西尾亮介, 田中敏博, 東倉洋一, 新川詔夫, 古山順一, 堀正二
Journal: Circulation (2006)
MITRAL AND AORTIC ACUTE PROSTHETIC VALVE THROMBOSIS IN A PATIENT WITH DISCORDANT APTT /ANTI-XA LEVELS
Authors: Fabio Solis-Jimenez, Jorge Reyes-Tovilla, Elias Terrazas, Montserrat Villalobos Pedroza, Cynthia Jackson-Pedroza, Jose Guadalajara-Boo
Journal: Journal of the American College of Cardiology (2021)
Preclinical Development and First-in-Human Study of KA2507, a Selective and Potent Inhibitor of Histone Deacetylase 6, for Patients with Refractory Solid Tumors
Authors: Apostolia M. Tsimberidou, Philip A. Beer, Carrie A. Cartwright, Cara Haymaker, Henry H. Vo, Simin Kiany, Alexander R.L. Cecil, James Dow, Kemal Haque, Franck A. Silva, Lucy Coe, Helen Berryman, Elisabeth A. Bone, Graciela M. Nogueras-Gonzalez, David Vining, Hilary McElwaine-Johnn, Ignacio I. Wistuba
Journal: Clinical Cancer Research (2021)

Inhibition of histone deacetylase 6 (HDAC6) is predicted to deliver both direct antitumor activity and modulation of the antitumor immune response. This study describes the development of a novel HDAC6 inhibitor.KA2507 was characterized in HDAC biochemical and cellular target engagement assays and in preclinical efficacy models of melanoma and colorectal cancer. In a phase I study, KA2507 was administered orally using a 3+3 dose-escalation design (NCT03008018).KA2507 is a potent and selective inhibitor of HDAC6 (biochemical IC50 = 2.5 nmol/L). Preclinical models demonstrated antitumor efficacy in syngeneic tumor-bearing mice, with translational studies highlighting modulation of the antitumor immune response. Twenty patients were treated in a phase I study. KA2507 was well tolerated; dose-limiting toxicity was not observed up to the maximum dose administered. Pharmacokinetic profiling supported twice-daily oral dosing. Pharmacodynamic analysis demonstrated selective HDAC6 target engagement in peripheral blood cells, free from off-target class I HDAC activity. Stable disease was the best clinical response (7 patients). Three of these patients (adenoid cystic carcinoma, n = 2; rectal adenocarcinoma, n = 1) had prolonged disease stabilization that lasted for 16.4, 12.6, and 9.0 months, respectively.KA2507 is a potent and selective inhibitor of HDAC6 showing antitumor efficacy and immune modulatory effects in preclinical models. In a phase I study, KA2507 showed selective target engagement, no significant toxicities, and prolonged disease stabilization in a subset of patients. Further clinical studies of KA2507 are warranted, as a single agent or, preferably, combined with other immuno-oncology drugs.
GENDER DISPARITY IN ACC/AHA/ESC/CCS GUIDELINES AUTHORSHIP FROM 2005-2019
Authors: Devesh Rai, Syed Hamza Waheed, Ankita Kapoor, Muhammad Waqas Tahir, Harsh Patel, Samarthkumar Thakkar, Ritambhara Pandey, Mallory Balmer-Swain, Erin Michos, Martha Gulati
Journal: Journal of the American College of Cardiology (2021)
Abstract 16040: Discrimination is Associated With High Cardiovascular Disease Risk: The African Immigrant Health Study
Authors: Ruth-Alma N Turkson-Ocran, Nwakaego A Nmezi, Yvonne Commodore-Mensah
Journal: Circulation (2019)

Background: Racial/ethnic minorities in the United States (U.S.), including persons of African descent, are disproportionately affected by cardiovascular diseases (CVD). Discrimination is associate...
RESOLVING UNCERTAINTIES IN AORTIC STENOSIS: THE IMPACT OF PRESSURE RECOVERY
Authors: Abhas Khurana, Adee Elhamdani, Jian Hu, Kirtivardhan Vashistha, Craig Alpert, Pietro Bajona, Srinivas Murali, Jennifer Keeley, Vinh Nguyen
Journal: Journal of the American College of Cardiology (2021)
Myocardial Histopathology in Patients With Obstructive Hypertrophic Cardiomyopathy
Authors: Hao Cui, Hartzell V. Schaff, Juliano Lentz Carvalho, Rick A. Nishimura, Jeffrey B. Geske, Joseph A. Dearani, Brian D. Lahr, Alexander T. Lee, J. Martijn Bos, Michael J. Ackerman, Steve R. Ommen, Joseph J. Maleszewski
Journal: Journal of the American College of Cardiology (2021)
Pharmacological Inhibition of Insulin Growth Factor-1 Receptor (IGF-1R) Alone or in Combination With Ruxolitinib Shows Therapeutic Efficacy in Preclinical Myeloproliferative Neoplasm Models
Authors: Titiksha Basu, Hannah Bertrand, Nikolaos Karantzelis, Albert Gründer, Heike L. Pahl
Journal: HemaSphere (2021)

Even after development of the JAK1/JAK2 inhibitor ruxolitinib, myeloproliferative neoplasm (MPN) patients require novel therapeutic options. While ruxolitinib can considerably improve quality of life and prolong survival, it does not modify the natural disease course in most patients. Moreover, resistance develops with prolonged use. Therefore, various combination treatments are currently being investigated. Published data provide a compelling rationale for the inhibition of insulin growth factor-1 receptor (IGF-1R) signaling in MPN. Here we report that genetic and pharmacological inhibition of IGF-1R selectively reduced Jak2 V617F -driven cytokine-independent proliferation ex vivo. Two different structurally unrelated IGF-1R inhibitors ameliorated disease phenotype in a murine MPN model and significantly prolonged survival. Moreover, in mice, low-dose ruxolitinib synergized with IGF-1R inhibition to increase survival. Our data demonstrate preclinical efficacy of IGF-1R inhibition in a murine MPN model.
Nitrate in Drinking Water during Pregnancy and Spontaneous Preterm Birth: A Retrospective Within-Mother Analysis in California
Authors: Allison R. Sherris, Michael Baiocchi, Scott Fendorf, Stephen P. Luby, Wei Yang, Gary M. Shaw
Journal: Environmental Health Perspectives (2021)

Background: Nitrate is a widespread groundwater contaminant and a leading cause of drinking water quality violations in California. Associations between nitrate exposure and select adverse birth outcomes have been suggested, but few studies have examined gestational exposures to nitrate and risk of preterm birth (before 37 wk gestation). Objective: We investigated the association between elevated nitrate in drinking water and spontaneous preterm birth through a within-mother retrospective cohort study of births in California. Methods: We acquired over 6 million birth certificate records linked with Office of Statewide Health Planning and Development hospital discharge data for California births from 2000–2011. We used public water system monitoring records to estimate nitrate concentrations in drinking water for each woman's residence during gestation. After exclusions, we constructed a sample of 1,443,318 consecutive sibling births in order to conduct a within-mother analysis. We used separate conditional logistic regression models to estimate the odds of preterm birth at 20–31 and 32–36 wk, respectively, among women whose nitrate exposure changed between consecutive pregnancies. Results: Spontaneous preterm birth at 20–31 wk was increased in association with tap water nitrate concentrations during pregnancy of 5 to <10mg/L [odds ratio (OR)=1.47; 95% confidence interval (CI): 1.29, 1.67] and ≥10mg/L (OR=2.52; 95% CI: 1.49, 4.26) compared with <5mg/L (as nitrogen). Corresponding estimates for spontaneous preterm birth at 32–36 wk were positive but close to the null for 5 to <10mg/L nitrate (OR=1.08; 95% CI: 1.02, 1.15) and for ≥10mg/L nitrate (OR=1.05; 95% CI: 0.85, 1.31) vs. <5mg/L nitrate. Our findings were similar in several secondary and sensitivity analyses, including in a conventional individual-level design. Discussion: The results suggest that nitrate in drinking water is associated with increased odds of spontaneous preterm birth. Notably, we estimated modestly increased odds associated with tap water nitrate concentrations of 5 to <10mg/L (below the federal drinking water standard of 10mg/L) relative to <5mg/L. https://doi.org/10.1289/EHP8205
Purtscher's retinopathy associated with acute pancreatitis
Authors: Ania M. Hamp, Edward Chu, William S. Slagle, Robert C. Hamp, Jeffrey T. Joy, Robert W. Morris
Journal: Circulation (2014)

PURPOSE Purtscher's retinopathy is a rare condition that is associated with complement-activating systemic diseases such as acute pancreatitis. After pancreatic injury or inflammation, proteases such as trypsin activate the complement system and can potentially cause coagulation and leukoembolization of retinal precapillary arterioles. Specifically, intermediate-sized emboli are sufficiently small enough to pass through larger arteries yet large enough to remain lodged in precapillary arterioles and cause the clinical appearance of Purtscher's retinopathy. This pathology may present with optic nerve edema, impaired visual acuity, visual field loss, as well as retinal findings such as cotton-wool spots, retinal hemorrhage, artery attenuation, venous dilation, and Purtscher flecken. CASE REPORT A 57-year-old white man presented with an acute onset of visual field scotomas and decreased visual acuity 1 week after being hospitalized for acute pancreatitis. The retinal examination revealed multiple regions of discrete retinal whitening surrounding the disk, extending through the macula bilaterally, as well as bilateral optic nerve hemorrhages. The patient identified paracentral bilateral visual field defects on Amsler Grid testing, which was confirmed with subsequent Humphrey visual field analysis. Although the patient presented with an atypical underlying etiology, he exhibited classic retinal findings for Purtscher's retinopathy. After 2 months, best corrected visual acuity improved and the retinal whitening was nearly resolved; however, bilateral paracentral visual field defects remained. CONCLUSIONS Purtscher's retinopathy has a distinctive clinical presentation and is typically associated with thoracic trauma but may be a sequela of nontraumatic systemic disease such as acute pancreatitis. Patients diagnosed with acute pancreatitis should have an eye examination to rule out Purtscher's retinopathy. Although visual improvement is possible, patients should be educated that there may be permanent ocular sequelae.
Coordinated β-globin expression and α2-globin reduction in a multiplex lentiviral gene therapy vector for β-thalassemia
Authors: Tiwaporn Nualkaew, Karine Sii-Felice, Marie Giorgi, Bradley McColl, Julie Gouzil, Astrid Glaser, Hsiao P.J. Voon, Hsin Y. Tee, George Grigoriadis, Saovaros Svasti, Suthat Fucharoen, Suradej Hongeng, Philippe Leboulch, Emmanuel Payen, Jim Vadolas
Journal: Molecular Therapy (2021)

A primary challenge in lentiviral gene therapy of β-hemoglobinopathies is to maintain low vector copy numbers to avoid genotoxicity while being reliably therapeutic for all genotypes. We designed a high-titer lentiviral vector, LVβ-shα2, that allows coordinated expression of the therapeutic βA-T87Q-globin gene and of an intron-embedded miR-30-based short hairpin RNA (shRNA) selectively targeting the α2-globin mRNA. Our approach was guided by the knowledge that moderate reduction of α-globin chain synthesis ameliorates disease severity in β-thalassemia. We demonstrate that LVβ-shα2 reduces α2-globin mRNA expression in erythroid cells while keeping α1-globin mRNA levels unchanged and βA-T87Q-globin gene expression identical to the parent vector. Compared with the first βA-T87Q-globin lentiviral vector that has received conditional marketing authorization, BB305, LVβ-shα2 shows 1.7-fold greater potency to improve α/β ratios. It may thus result in greater therapeutic efficacy and reliability for the most severe types of β-thalassemia and provide an improved benefit/risk ratio regardless of the β-thalassemia genotype. A primary challenge in lentiviral gene therapy of β-hemoglobinopathies is to maintain low vector copy numbers to avoid genotoxicity while being reliably therapeutic for all genotypes. We designed a high-titer lentiviral vector, LVβ-shα2, that allows coordinated expression of the therapeutic βA-T87Q-globin gene and of an intron-embedded miR-30-based short hairpin RNA (shRNA) selectively targeting the α2-globin mRNA. Our approach was guided by the knowledge that moderate reduction of α-globin chain synthesis ameliorates disease severity in β-thalassemia. We demonstrate that LVβ-shα2 reduces α2-globin mRNA expression in erythroid cells while keeping α1-globin mRNA levels unchanged and βA-T87Q-globin gene expression identical to the parent vector. Compared with the first βA-T87Q-globin lentiviral vector that has received conditional marketing authorization, BB305, LVβ-shα2 shows 1.7-fold greater potency to improve α/β ratios. It may thus result in greater therapeutic efficacy and reliability for the most severe types of β-thalassemia and provide an improved benefit/risk ratio regardless of the β-thalassemia genotype.
STARTING A GENERAL CARDIOVASCULAR FELLOWSHIP AT A COMMUNITY HOSPITAL SIGNIFICANTLY IMPROVED CATH LAB QUALITY MEASURES WITHOUT NEGATIVELY IMPACTING LENGTH OF STAY
Authors: George Skaf, Diana Daftari, Samantha Gelman, Javad Savoj, Denise Palmatier, Napatkamon Ayutyanont, Mimi Biswas, Patrick Hu
Journal: Journal of the American College of Cardiology (2021)
Wireless, Skin‐Interfaced Devices for Pediatric Critical Care: Application to Continuous, Noninvasive Blood Pressure Monitoring
Authors: Claire Liu, Jin‐Tae Kim, Sung Soo Kwak, Aurelie Hourlier‐Fargette, Raudel Avila, Jamie Vogl, Andreas Tzavelis, Ha Uk Chung, Jong Yoon Lee, Dong Hyun Kim, Dennis Ryu, Kelsey B. Fields, Joanna L. Ciatti, Shupeng Li, Masahiro Irie, Allison Bradley, Avani Shukla, Jairo Chavez, Emma C. Dunne, Seung Sik Kim, Jungwoo Kim, Jun Bin Park, Han Heul Jo, Joohee Kim, Michael C. Johnson, Jean Won Kwak, Surabhi R. Madhvapathy, Shuai Xu, Casey M. Rand, Lauren E. Marsillio, Sue J. Hong, Yonggang Huang, Debra E. Weese‐Mayer, John A. Rogers
Journal: Advanced Healthcare Materials (2021)

Abstract Indwelling arterial lines, the clinical gold standard for continuous blood pressure (BP) monitoring in the pediatric intensive care unit (PICU), have significant drawbacks due to their invasive nature, ischemic risk, and impediment to natural body movement. A noninvasive, wireless, and accurate alternative would greatly improve the quality of patient care. Recently introduced classes of wireless, skin‐interfaced devices offer capabilities in continuous, precise monitoring of physiologic waveforms and vital signs in pediatric and neonatal patients, but have not yet been employed for continuous tracking of systolic and diastolic BP—critical for guiding clinical decision‐making in the PICU. The results presented here focus on materials and mechanics that optimize the system‐level properties of these devices to enhance their reliable use in this context, achieving full compatibility with the range of body sizes, skin types, and sterilization schemes typically encountered in the PICU. Systematic analysis of the data from these devices on 23 pediatric patients, yields derived, noninvasive BP values that can be quantitatively validated against direct recordings from arterial lines. The results from this diverse cohort, including those under pharmacological protocols, suggest that wireless, skin‐interfaced devices can, in certain circumstances of practical utility, accurately and continuously monitor BP in the PICU patient population.
PATIENT REPORTED FUNCTIONAL STATUS AS A PREDICTOR FOR N-TERMINAL PRO-BRAIN NATRIURETIC PEPTIDE (NT-PROBNP) AND CARDIOVASCULAR HOSPITALIZATIONS IN PATIENTS WITH STABLE ISCHEMIC HEART DISEASE: A REPORT FROM THE PREDICTION, RISK, AND EVALUATION OF MAJOR ADVERSE CARDIAC EVENTS (PRE-MACE) STUDY
Authors: Benita Tjoe, Gillian Gresham, Sandy Joung, Corey Arnold, Shivani Dhawan, Garth Fuller, William Speier, Mitra Mastali, Kelly Mouapi, Irene van den Broek, Janet Wei, Brennan Spiegel, Jennifer Van Eyk, C. Noel Bairey Merz, Chrisandra Shufelt
Journal: Journal of the American College of Cardiology (2021)