tbuckley/cabot-search huggingface dataset:
Nocturnal hypoxaemia in interstitial lung disease: a systematic review
Authors: Yet Hong Khor, Yvonne Ng, Duncan Sweeney, Christopher J Ryerson
Journal: Thorax (2021)

Patients with interstitial lung disease (ILD) are at risk of developing nocturnal hypoxaemia due to ventilatory restriction and impaired gas exchange that worsen with supine posture and reduced ventilatory drive during sleep. This systematic review synthesised literature on the diagnostic evaluation, epidemiology, associations, management and prognosis of nocturnal hypoxaemia in ILD.Ovid MEDLINE, Embase and CENTRAL databases were searched for eligible studies. Meta-analyses with subgroup analyses were conducted, where possible.Fifty-three studies were included (total participant number=2590). The most common definition for clinically significant nocturnal hypoxaemia was ≥10% of total sleep time with oxyhaemoglobin saturation <90%, with pooled prevalence of 37%. There were no significant differences in pooled prevalence according to ILD subtype and comorbid obstructive sleep apnoea status. Study heterogeneity precluded meta-analysis of associations and prognosis. Diffusing capacity for carbon monoxide (DLCO) and echocardiographic features for pulmonary hypertension were consistently associated with nocturnal hypoxaemia. There were inconsistent associations between nocturnal hypoxaemia with ILD subtype and severity. Multivariable analyses in most studies demonstrated significant associations of nocturnal hypoxaemia with survival. Two small short-term intervention studies demonstrated that supplemental oxygen of 1-3 L/min corrected nocturnal hypoxaemia, with improved heart rate control during in-laboratory observation and increased serum antioxidant levels after 1 month of therapy.Nocturnal hypoxaemia is common, associated with DLCO impairment and markers suggestive of pulmonary hypertension, and a potential prognostic factor in patients in ILD. There is a need to establish a consensus definition of nocturnal hypoxaemia and evaluate long-term effects of nocturnal supplemental oxygen in ILD.
An Open-Label Study of Pegylated Liposomal Doxorubicin, Vincristine and Reduced-Dose Dexamethasone Combination Therapy in Newly Diagnosed Multiple Myeloma Patients in Chinese Population.
Authors: Yang Shen, Zhixiang Shen, Bin Jiang, Jian Hou, Rong Zhan, Lugui Qiu, Yongji Wu, Jie Jin, Juan Li, Fanyi Meng, Ping Zou, Ting Liu, Jianyong Li, Chun Wang, Depai Wu, Jun Ma
Journal: Blood (2007)
Delayed production of neutralizing antibodies correlates with fatal COVID-19
Authors: Carolina Lucas, Jon Klein, Maria E. Sundaram, Feimei Liu, Patrick Wong, Julio Silva, Tianyang Mao, Ji Eun Oh, Subhasis Mohanty, Jiefang Huang, Maria Tokuyama, Peiwen Lu, Arvind Venkataraman, Annsea Park, Benjamin Israelow, Chantal B. F. Vogels, M. Catherine Muenker, C-Hong Chang, Arnau Casanovas-Massana, Adam J. Moore, Joseph Zell, John B. Fournier, Abeer Obaid, Alexander James Robertson, Alice Lu-Culligan, Alice Zhao, Allison Nelson, Anderson Brito, Angela Nunez, Anjelica Martin, Anne E. Watkins, Bertie Geng, Caitlin J. Chun, Chaney C. Kalinich, Christina A. Harden, Codruta Todeasa, Cole Jensen, Coriann E. Dorgay, Daniel Kim, David McDonald, Denise Shepard, Edward Courchaine, Elizabeth B. White, Eric Song, Erin Silva, Eriko Kudo, Giuseppe DeIuliis, Harold Rahming, Hong-Jai Park, Irene Matos, Isabel Ott, Jessica Nouws, Jordan Valdez, Joseph Fauver, Joseph Lim, Kadi-Ann Rose, Kelly Anastasio, Kristina Brower, Laura Glick, Lokesh Sharma, Lorenzo Sewanan, Lynda Knaggs, Maksym Minasyan, Maria Batsu, Mary Petrone, Maxine Kuang, Maura Nakahata, Melissa Linehan, Michael H. Askenase, Michael Simonov, Mikhail Smolgovsky, Natasha C. Balkcom, Nicole Sonnert, Nida Naushad, Pavithra Vijayakumar, Rick Martinello, Rupak Datta, Ryan Handoko, Santos Bermejo, Sarah Prophet, Sean Bickerton, Sofia Velazquez, Tara Alpert, Tyler Rice, William Khoury-Hanold, Xiaohua Peng, Yexin Yang, Yiyun Cao, Yvette Strong, Zitong Lin, Anne L. Wyllie, Melissa Campbell, Alfred I. Lee, Hyung J. Chun, Nathan D. Grubaugh, Wade L. Schulz, Shelli Farhadian, Charles Dela Cruz, Aaron M. Ring, Albert C. Shaw, Adam V. Wisnewski, Inci Yildirim, Albert I. Ko, Saad B. Omer, Akiko Iwasaki
Journal: Nature Medicine (2021)
Randomised controlled trial of oxygen therapy and high-flow nasal therapy in African children with pneumonia
Authors: K. Maitland, S. Kiguli, P. Olupot-Olupot, M. Hamaluba, K. Thomas, F. Alaroker, R. O. Opoka, A. Tagoola, V. Bandika, A. Mpoya, H. Mnjella, E. Nabawanuka, W. Okiror, M. Nakuya, D. Aromut, C. Engoru, E. Oguda, T. N. Williams, J. F. Fraser, D. A. Harrison, K Rowan
Journal: Intensive Care Medicine (2021)

The life-saving role of oxygen therapy in African children with severe pneumonia is not yet established.The open-label fractional-factorial COAST trial randomised eligible Ugandan and Kenyan children aged > 28 days with severe pneumonia and severe hypoxaemia stratum (SpO2 < 80%) to high-flow nasal therapy (HFNT) or low-flow oxygen (LFO: standard care) and hypoxaemia stratum (SpO2 80-91%) to HFNT or LFO (liberal strategies) or permissive hypoxaemia (ratio 1:1:2). Children with cyanotic heart disease, chronic lung disease or > 3 h receipt of oxygen were excluded. The primary endpoint was 48 h mortality; secondary endpoints included mortality or neurocognitive sequelae at 28 days.The trial was stopped early after enrolling 1852/4200 children, including 388 in the severe hypoxaemia stratum (median 7 months; median SpO2 75%) randomised to HFNT (n = 194) or LFO (n = 194) and 1454 in the hypoxaemia stratum (median 9 months; median SpO2 88%) randomised to HFNT (n = 363) vs LFO (n = 364) vs permissive hypoxaemia (n = 727). Per-protocol 15% of patients in the permissive hypoxaemia group received oxygen (when SpO2 < 80%). In the severe hypoxaemia stratum, 48-h mortality was 9.3% for HFNT vs. 13.4% for LFO groups. In the hypoxaemia stratum, 48-h mortality was 1.1% for HFNT vs. 2.5% LFO and 1.4% for permissive hypoxaemia. In the hypoxaemia stratum, adjusted odds ratio for 48-h mortality in liberal vs permissive comparison was 1.16 (0.49-2.74; p = 0.73); HFNT vs LFO comparison was 0.60 (0.33-1.06; p = 0.08). Strata-specific 28 day mortality rates were, respectively: 18.6, 23.4 and 3.3, 4.1, 3.9%. Neurocognitive sequelae were rare.Respiratory support with HFNT showing potential benefit should prompt further trials.
Socioeconomic inequalities in co-morbidity of overweight, obesity and mental ill-health from adolescence to mid-adulthood in two national birth cohort studies
Authors: Amal R. Khanolkar, Praveetha Patalay
Journal: The Lancet Regional Health - Europe (2021)

To examine socioeconomic inequalities in comorbidity risk for overweight (including obesity) and mental ill-health in two national cohorts. We investigated independent effects of childhood and adulthood socioeconomic disadvantage on comorbidity from childhood to mid-adulthood, and differences by sex and cohort. Data were from 1958 National Child Development Study (NCDS58) and 1970 British Cohort Study (BCS70) [total N=30,868, 51% males] assessed at ages 10, 16, 23/26, 34 and 42 years. Socioeconomic indicators included childhood and adulthood social class and educational level. Risk for i. having healthy BMI and mental ill-health, ii. overweight and good mental health, and iii. overweight and mental ill-health was analysed using multinomial logistic regression. Socioeconomic disadvantage was consistently associated with greater risk for overweight-mental ill-health comorbidity at all ages (RRR 1.43, 2.04, 2.38, 1.64 and 1.71 at ages 10, 16, 23, 34 and 42 respectively for unskilled/skilled vs. professional/managerial class). The observed inequalities in co-morbidity were greater than those observed for either condition alone (overweight; RRR 1.39 and 1.25, mental ill-health; 1.36 and 1.22 at ages 16 and 42 respectively, for unskilled/skilled vs. professional/managerial class). In adulthood, both childhood and adulthood socioeconomic disadvantage were independently associated with comorbid overweight-mental ill-health, with a clear inverse gradient between educational level and risk for comorbidity. For instance, for the no education group (compared to university education) the RRR is 6.11 (95% CI 4.31-8.65) at age 34 and 4.42 (3.28-5.96) at age 42. There were no differences observed in the extent of inequalities by sex and differences between cohorts were limited. While socioeconomic disadvantage in childhood and adulthood are consistently and independently associated with greater risk for mental ill-health and being overweight separately, these associations are even larger for their comorbidity across the lifecourse. These findings are significant given the increasing global prevalence of obesity and mental ill-health, and their implications for lifelong health and mortality. This research was supported by grants from the Wellcome Trust (ISSF3/ H17RCO/NG1) and Medical Research Council (MRC) [MC_UU_00019/3].
Annals Graphic Medicine - The Social Impact of COVID-19
Authors: Sujal Manohar
Journal: Annals of Internal Medicine (2021)

Web Exclusives4 May 2021Annals Graphic Medicine - The Social Impact of COVID-19FREESujal Manohar, BS, BASujal Manohar, BS, BADuke University, Durham, North Carolina (S.M.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/G21-0022 SectionsAboutVisual AbstractPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Download figure Download PowerPoint Download figure Download PowerPoint Download figure Download PowerPoint Author, Article, and Disclosure InformationAuthors: Sujal Manohar, BS, BAAffiliations: Duke University, Durham, North Carolina (S.M.)Disclosures: The author has reported no disclosures of interest. The form can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=G21-0022.Author/Illustrator Information: Sujal Manohar, BS, BA, is a Duke University Hart Fellow. She will start medical school in 2021 (e-mail, sujal_manohar@hotmail.com or sujal.manohar@duke.edu).This article was published at Annals.org on 4 May 2021. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics June 2021Volume 174, Issue 6 Page: W60-W62 ePublished: 4 May 2021 Issue Published: June 2021 Copyright & PermissionsCopyright © 2021 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
GIMAP5 maintains liver endothelial cell homeostasis and prevents portal hypertension
Authors: Kaela Drzewiecki, Jungmin Choi, Joseph Brancale, Michael A. Leney-Greene, Sinan Sari, Buket Dalgiç, Aysel Ünlüsoy Aksu, Gülseren Evirgen Şahin, Ahmet Ozen, Safa Baris, Elif Karakoc-Aydiner, Dhanpat Jain, David Kleiner, Michael Schmalz, Kadakkal Radhakrishnan, Junhui Zhang, Kasper Hoebe, Helen C. Su, João P. Pereira, Michael J. Lenardo, Richard P. Lifton, Sílvia Vilarinho
Journal: The Journal of Experimental Medicine (2021)

Portal hypertension is a major contributor to decompensation and death from liver disease, a global health problem. Here, we demonstrate homozygous damaging mutations in GIMAP5, a small organellar GTPase, in four families with unexplained portal hypertension. We show that GIMAP5 is expressed in hepatic endothelial cells and that its loss in both humans and mice results in capillarization of liver sinusoidal endothelial cells (LSECs); this effect is also seen when GIMAP5 is selectively deleted in endothelial cells. Single-cell RNA-sequencing analysis in a GIMAP5-deficient mouse model reveals replacement of LSECs with capillarized endothelial cells, a reduction of macrovascular hepatic endothelial cells, and places GIMAP5 upstream of GATA4, a transcription factor required for LSEC specification. Thus, GIMAP5 is a critical regulator of liver endothelial cell homeostasis and, when absent, produces portal hypertension. These findings provide new insight into the pathogenesis of portal hypertension, a major contributor to morbidity and mortality from liver disease.
MACHINE LEARNING MODEL FOR IN-HOSPITAL MORTALITY PREDICTION AFTER TRANSCATHETER AORTIC VALVE REPLACEMENT
Authors: Chayakrit Krittanawong, Hafeez Ul Hassan Virk, Joshua Hahn, Fu’ad Al-Azzam, Kevin Greason, Ameesh Isath, Bing Yue, Scott Kaplin, Matthew Stewart, Mahboob Alam, Samin Sharma
Journal: Journal of the American College of Cardiology (2021)
COMPARATIVE PROGNOSTIC VALUE OF AN INITIAL COMPUTED TOMOGRAPHY ANGIOGRAPHY VS MYOCARDIAL PERFUSION IMAGING APPROACH IN PATIENTS WITH CORONARY ARTERY DISEASE
Authors: Ahmed Ibrahim Ahmed, Yushui Han, Faisal Nabi, Su Min Chang, Talal Alnabelsi, Hassaan Arshad, John Mahmarian, Mouaz Al-Mallah
Journal: Journal of the American College of Cardiology (2021)
SAFETY AND EFFICACY OF MECHANICAL ESOPHAGEAL DEVIATION DURING CATHETER ABLATION PROCEDURES: A SYSTEMATIC REVIEW AND METAANALYSIS OF OBSERVATIONAL STUDIES
Authors: Ahmed Elzanaty, Sapan Bhuta, Neha Patel, Omar Sajdeya, Mohammed Mhanna, Cameron Burmeister, Pinang Shastri, Jeremy Tomcho, Mitra Patel, Sami Ghazaleh, Eman Elsheikh, Paul Chako
Journal: Journal of the American College of Cardiology (2021)
Energy Harvesting Untethered Soft Electronic Devices
Authors: Kyun Kyu Kim, Joonhwa Choi, Seung Hwan Ko
Journal: Advanced Healthcare Materials (2021)

Abstract Advances in wearable and stretchable electronic technologies have yielded a wide range of electronic devices that can be conformably worn by, or implanted in humans to measure physiological signals. Moreover, various cutting‐edge technologies for battery‐free electronic devices have led to advances in healthcare devices that can continuously measure long‐term biosignals for advanced human–machine interface and clinical diagnostics. This report presents the recent progress in battery‐less, wearable devices using a wide range of energy harvesting sources, such as electromagnetic energy, mechanical energy, and biofuels. Additionally, this report also discusses the principles and working mechanisms of near/far‐field communications, triboelectric, thermoelectric, and biofuel technologies.
Response to a letter to the editor regarding “limitations of using the National Cancer Database to examine the effect of policy change on stage at presentation at the population-level”
Authors: Richard J. Straker, Yun Song, Adrienne B. Shannon, Emily Y. Chu, John T. Miura, Michael E. Ming, Giorgos C. Karakousis
Journal: Journal of the American Academy of Dermatology (2021)
Characteristics and Survival of Patients with Chronic Phase Myelofibrosis and Elevated Blasts (5-9%), and the Effect of Therapy with JAK2 Inhibitor Ruxolitinib
Authors: Lucia Masarova, Prithviraj Bose, Naveen Pemmaraju, Naval Daver, Jorge E. Cortes, Zeev Estrov, Hagop M. Kantarjian, Srdan Verstovsek
Journal: Blood (2017)
Risk Factors With Neurotoxicity After Chimeric Antigen Receptor T-Cell Therapy—Reply
Authors: Daniel B. Rubin, Caron Jacobson, Henrikas Vaitkevicius
Journal: JAMA Neurology (2021)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Neurology HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Neurology journal
WRONG BUG AT WRONG PLACE: AN UNCOMMON CASE OF METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS PERICARDITIS
Authors: Sreekant Avula, Sujithraj Dommaraju, Purveshkumar Patel, Kashyap Kela, Tapan Buch, Milos Babic
Journal: Journal of the American College of Cardiology (2021)
ASSESSING DIFFUSE CORONARY ATHEROSCLEROSIS IN SUBJECTS WITH IMPAIRED CORONARY FLOW RESERVE BUT NO ANGIOGRAPHIC CRITICAL STENOSIS. A TRANSTHORACIC ENHANCED COLOR DOPPLER ECHOCARDIOGRAPHYC STUDY
Authors: Carlo Caiati, Paola Siena, Fortunato Iacovelli, Laura Piscitelli, Paolo Pollice, Stefano Favale, Mario Erminio Lepera
Journal: Journal of the American College of Cardiology (2021)
EFFECT OF ESCIN, THE ACTIVE INGREDIENT OF HORSE CHESTNUT SEED EXTRACT ON ATHEREROSCLEROTIC PLAGUE STABILIZATION
Authors: Arjun Prasad, Kipp Johnson, Jagat Narula, Artiom Petrov, Yuliya Vangrenyuk, Navneet Narula, Koon Yan Pak, Brian Gray, Harry Strauss, Joel Dudley, Annapoorna Kini
Journal: Journal of the American College of Cardiology (2021)
Plasma membrane targeted photodynamic O2 economizer for hypoxic tumor therapy
Authors: Gui-Ling Fan, Fu-An Deng, Xiang Zhou, Ling-Shan Liu, Jia-Qi Huang, Da-Wei Zhang, Yun-Xia Sun, A-Li Chen, Hong Cheng, Shi-Ying Li
Journal: Biomaterials (2021)
BECLIN 1 KNOCKDOWN ATTENUATED HIGH FATTY DIET-INDUCED CARDIOMYOPATHY BY ACTIVATING RAB9-DEPENDENT ALTERNATIVE AUTOPHAGY PATHWAY
Authors: Xiaofang Zeng, Anandharajan Rathinasabapathy, Xihui Xu, Famei Li, Jun Ren, Zaixin Yu, Xiangwei Liu
Journal: Journal of the American College of Cardiology (2021)
TAVR IN A PATIENT WITH SEVERE AORTIC REGURGITATION AND PANCYTOPENIA, AS A LIFESAVING PROCEDURE
Authors: Julia Grapsa, Tiffany Patterson, Michael Ghosh, Harriet Hurrell, Zilan Demir, Christopher Allen, Nicholas Aroney, Gianluca Lucchese, Christopher Young, Jane Hancock, Ronak Rajani, Simon Redwood, Bernard Prendergast
Journal: Journal of the American College of Cardiology (2021)
Dynamics of sputum conversion during effective tuberculosis treatment: A systematic review and meta-analysis
Authors: Claire J. Calderwood, James P. Wilson, Katherine L. Fielding, Rebecca C. Harris, Aaron S. Karat, Raoul Mansukhani, Jane Falconer, Malin Bergstrom, Sarah M. Johnson, Nicky McCreesh, Edward J. M. Monk, Jasantha Odayar, Peter J. Scott, Sarah A. Stokes, Hannah Theodorou, David A. J. Moore
Journal: PLoS Medicine (2021)

Two weeks' isolation is widely recommended for people commencing treatment for pulmonary tuberculosis (TB). The evidence that this corresponds to clearance of potentially infectious tuberculous mycobacteria in sputum is not well established. This World Health Organization-commissioned review investigated sputum sterilisation dynamics during TB treatment.
Modification of Heritability for Educational Attainment and Fluid Intelligence by Socioeconomic Deprivation in the UK Biobank
Authors: Mathias Rask-Andersen, Torgny Karlsson, Weronica E. Ek, Åsa Johansson
Journal: American Journal of Psychiatry (2021)

Objective: Socioeconomic factors have been suggested to influence the effect of education- and intelligence-associated genetic variants. However, results from previous studies on the interaction between socioeconomic status and education or intelligence have been inconsistent. The authors sought to assess these interactions in the UK Biobank cohort of 500,000 participants. Methods: The authors assessed the effect of socioeconomic deprivation on education- and intelligence-associated genetic variants by estimating the single-nucleotide polymorphism (SNP) heritability for fluid intelligence, educational attainment, and years of education in subsets of UK Biobank participants with different degrees of social deprivation, using linkage disequilibrium score regression. They also generated polygenic scores with LDpred and tested for interactions with social deprivation. Results: SNP heritability increased with socioeconomic deprivation for fluid intelligence, educational attainment, and years of education. Polygenic scores were also found to interact with socioeconomic deprivation, where the effects of the scores increased with increasing deprivation for all traits. Conclusions: These results indicate that genetics have a larger influence on educational and cognitive outcomes in more socioeconomically deprived U.K. citizens, which has serious implications for equality of opportunity.
TRANSCATHETER TRICUSPID VALVE-IN-VALVE REPLACEMENT FOLLOWING LASER LEAD EXTRACTION IN PATIENT WITH ORTHOTOPIC HEART TRANSPLANT AND FAILED BIOPROSTHETIC TRICUSPID VALVE
Authors: Aaron Lee, Adekunle Kiladejo, Jean Gue, Fredric Ginsberg, Sajjad Sabir, John Andriulli, Janah Aji
Journal: Journal of the American College of Cardiology (2021)
Variable Emergence of Autism Spectrum Disorder Symptoms From Childhood to Early Adulthood
Authors: Lucy Riglin, Robyn E. Wootton, Ajay K. Thapar, Lucy A. Livingston, Kate Langley, Stephan Collishaw, Jack Tagg, George Davey Smith, Evie Stergiakouli, Kate Tilling, Anita Thapar
Journal: American Journal of Psychiatry (2021)

Objective: Autism spectrum disorder (ASD) is currently considered an early-onset neurodevelopmental condition. Follow-up studies of clinic-ascertained autism suggest that autistic symptoms typically decline with age, although symptom improvement is limited for some. To date there have been no population-based prospective studies investigating the natural history of autistic symptoms from childhood to adulthood. The aim of this study was to characterize the development and heterogeneity of autistic symptoms in a population-based cohort from childhood to age 25. Methods: Data were analyzed in a prospective U.K. population-based cohort (ALSPAC). Trajectories were derived using five assessments of the parent-rated Social and Communication Disorders Checklist (SCDC) spanning ages 7–25. Additional measures were used to validate symptom trajectories. Results: Three distinct SCDC symptom trajectory classes were identified: low (88.5%), declining (5.0%), and late-emerging (6.5%). Both the declining and late-emerging trajectory classes were associated with child and adult ASD measures, low IQ, communication problems, peer problems, and worse adult functioning compared with the low trajectory class. Male sex was associated with a higher likelihood of being in the declining trajectory class (odds ratio=2.84, 95% CI=2.19, 3.69). This sex difference was not observed in the late-emerging class (odds ratio=1.00, 95% CI=0.80, 1.24) compared with the low trajectory class. Conclusions: ASD symptom levels that emerged early tended to decline across development, although impairment was still present in adulthood for some. For others, autistic symptoms emerged across adolescence and adulthood. This challenges our current understanding that ASD symptoms inevitably first manifest early in development.
HEMODYNAMIC AND ANATOMIC CHANGES AFTER FETAL AORTIC VALVULOPLASTY ARE ASSOCIATED WITH PROCEDURAL SUCCESS AND POSTNATAL BIVENTRICULAR CIRCULATION
Authors: Victoria Robson, Wayne Tworetzky, Ryan Callahan, Louise Wilkins-Haug, Carol Benson, Diego Porras, Stephanie Guseh, Minmin Lu, Lynn Sleeper, Kevin Friedman
Journal: Journal of the American College of Cardiology (2021)