tbuckley/cabot-search huggingface dataset:
Reply
Authors: J. Warner, B. Clements
Journal: Thorax (1987)

The crossover lung segment: congenital malformation associated with a variant of scimitar syndrome SIR,-In their paper (June 1987;42:417-9) Drs BS Clements and JO Warner make the statement that the crossover lung segment in association with a variant of the scimitar syn- drome has not previously been described but this is incorrect.Their description is, in all essentials, that of horseshoe lung.'
A patient with Kartagener and Paterson-Brown-Kelly syndromes
Authors: N. W. Todd
Journal: JAMA (1975)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Idiopathic pericarditis without symptoms
Authors: M. Mirowski
Journal: JAMA (1967)

PATIENTS with idiopathic pericarditis usually complain of chest pain, dyspnea, fever, and malaise. Although the intensity of these symptoms may vary and may in fact be very low,<sup>1</sup>no report of a completely asymptomatic case was found in the literature. Recently, one such patient has been observed, and because of the case's apparent rarity and eventual implications it was considered to be worthwhile reporting. <h3>Report of a Case</h3> An 8 1/2-year-old boy was referred to the pediatric department on Dec 22, 1965, because of a marked enlargement of the heart incidentally discovered at a routine x-ray examination. The patient, one of probably homozygous twins, had nothing of significance in his or his family's history except that he was prone to repeated upperrespiratory tract infections. He was suffering from enlarged adenoids, and prior to their removal, a routine chest roentgenogram was made. Physical examination revealed a well-developed, wellnourished, active, and
Error in Figure and Text
Journal: JAMA Internal Medicine (2015)

Katherine A. Ornstein, PhD, MPH; Bruce Leff, MD; Kenneth E. Covinsky, MD; Christine S. Ritchie, MD, MSPH; Alex D. Federman, MD, MPH; Laken Roberts, MPH; Amy S. Kelley, MD, MSHS; Albert L. Siu, MD, MSPH; Sarah L. Szanton, PhD
Acute leukemia with Ph1-like chromosome in an LSD user
Authors: L. Grossbard
Journal: JAMA (1968)

Acute leukemia occurred in a user of several hallucinogenic drugs (lysergic acid diethylamide [LSD], mescaline, marihuana, and amphetamines). The leukemic leukocytes of the patient contained a Ph<sup>1</sup>-like chromosome; lymphocytes transformed with phytohemagglutinin did not show chromosome breaks. A Ph<sup>1</sup>-like chromosome has only rarely been reported in either acute leukemia or in cultured lymphocytes of individuals ingesting LSD.
Chemical and biochemical approaches in the study of histone methylation and demethylation
Authors: Keqin Kathy Li, Cheng Luo, Dongxia Wang, Hualiang Jiang, Y. George Zheng
Journal: Medicinal Research Reviews (2010)

Histone methylation represents one of the most critical epigenetic events in DNA function regulation in eukaryotic organisms. Classic molecular biology and genetics tools provide significant knowledge about mechanisms and physiological roles of histone methyltransferases and demethylases in various cellular processes. In addition to this stream line, development and application of chemistry and chemistry-related techniques are increasingly involved in biological study, and offer information otherwise difficult to obtain by standard molecular biology methods. Herein, we review recent achievements and progress in developing and applying chemical and biochemical approaches in the study of histone methylation, including chromatin immunoprecipitation, chemical ligation, mass spectrometry, biochemical methylation and demethylation assays, and inhibitor development. These technological advances allow histone methylation to be studied from genome-wide level to molecular and atomic levels. With ChIP technology, information can be obtained about precise mapping of histone methylation patterns at specific promoters, genes, or other genomic regions. MS is particularly useful in detecting and analyzing methylation marks in histone and nonhistone protein substrates. Chemical approaches that permit site-specific incorporation of methyl groups into histone proteins greatly facilitate the investigation of biological impacts of methylation at individual modification sites. Discovery and design of selective organic inhibitors of histone methyltransferases and demethylases provide chemical probes to interrogate methylation-mediated cellular pathways. Overall, these chemistry-related technological advances have greatly improved our understanding of the biological functions of histone methylation in normal physiology and diseased states, and also are of great potential to translate basic epigenetics research into diagnostic and therapeutic applications in the clinic. © 2010 Wiley Periodicals, Inc. Med Res Rev., 32, No. 4, 815-867, 2012
The Carcinogenicity of Beryllium
Authors: Marvin Kuschner
Journal: Environmental Health Perspectives (1981)

Beryllium, some of its alloys, and a variety of its compounds have induced malignant tumors of the lung and osteogenic sarcoma in experimental animals. Three animal species, monkeys, rabbits, and rats, have been shown to be susceptible. Beryllium induces morphological transformation in mammalian cells and enhances viral transformation of mammalian cells. It has been shown to decrease fidelity of DNA synthesis. It has been recognized that exposure to compounds of this metal will, in some individuals, result in a chronic granulomatous disease of the lung. A series of overlapping recent human epidemiological studies have been suggestive of an increase in the incidence of lung cancer in populations occupationally exposed to beryllium. Such studies, together with animal and in vitro studies, argue for the strong presumption of a carcinogenic hazard to man in occupational beryllium exposures.
Carbenicillin therapy for pseudomonas infections
Authors: G. P. Bodey
Journal: JAMA (1971)

Carbenicillin disodium was effective in the treatment of 91% (54) of 59 infections caused by<i>Pseudomonas</i>organisms. However, 7% (4) of the infections responded only partially, and 10% (6) relapsed when therapy was discontinued. The response rate and relapse rate did not correlate very closely with the results of in vitro sensitivity testing. Only 7% (4) of the strains of pseudomonas became resistant during carbenicillin therapy, and there has been no major increases in carbenicillin-resistant isolates at the University of Texas M. D. Anderson Hospital and Tumor Institute since the widespread usage of this antibiotic was begun. The frequency of pseudomonas as a cause of fatal infection in adults with leukemia has decreased from 31% to 8% (8 deaths) since carbenicillin has been introduced. Superinfection occurred in 17% (10) of the patients receiving this drug. Toxic effects were minimal and consisted mainly of transient elevations in serum glutamic oxaloacetic transaminase and serum glutamic pyruvic transaminase levels.
The preservation of human cadaver kidneys for transplantation
Authors: R. E. McCabe
Journal: JAMA (1972)

In order to provide a larger number of cadaver kidneys for transplantation in New York City, a regional program in organ procurement, preservation, and tissue typing was instituted in a cooperative effort between multiple dialysis units and the transplant centers. During the past year, ten different hospitals provided 30 kidneys to the organ pool. After perfusion, preservation, and testing, 20 of these were selected for transplantation at five different centers. Tissue typing of the recipient pool of more than 200 was performed by the New York Blood Center. Short-term graft survival rate approaches 85%. An even broader physician participation in the regional organ procurement program is encouraged and expected in the future so that there might be a substantial reduction in the duration a dialysis patient must await a cadaver transplant.
Metabolic carotenaemia
Authors: B.E. MONK
Journal: British Journal of Dermatology (1982)

Journal Article Metabolic carotenaemia Get access B.E. MONK B.E. MONK Department of Dermatology, Royal Free Hospital, London NW3 Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 106, Issue 4, 1 April 1982, Pages 485–488, https://doi.org/10.1111/j.1365-2133.1982.tb04546.x Published: 01 April 1982 Article history Accepted: 20 June 1981 Published: 01 April 1982
Aspirin increases blood alcohol concentrations in humans after ingestion of ethanol
Authors: R. Roine
Journal: JAMA (1990)

Gastric first-pass metabolism of ethanol is an important determinant of blood alcohol concentrations. We studied five healthy volunteers after ingestion of ethanol (0.3 g/kg of body weight) and found that blood alcohol concentrations in the fed state (ie, 1 hour after a standard breakfast) were significantly higher when the subjects received 1 g of aspirin 1 hour before ingestion of ethanol than without the drug. In vitro, aspirin clearly decreased the activity of gastric alcohol dehydrogenase in human subjects and in rat models, but not that of hepatic alcohol dehydrogenase in rats. Furthermore, blood alcohol concentrations in rats were unaffected by ingestion of aspirin when ethanol was infused intravenously. Thus, aspirin may increase the bioavailability of ingested ethanol in humans, possibly by reducing ethanol oxidation by gastric alcohol dehydrogenase. (<i>JAMA</i>. 1990;264:2406-2408)
Hodgkin’s Disease in the Elderly: Improved Treatment Outcome With a Doxorubicin-Containing Regimen
Authors: Colin D. Weekes, Julie M. Vose, Jim C. Lynch, Dennis D. Weisenburger, Philip J. Bierman, Timothy Greiner, Gregory Bociek, Charles Enke, Martin Bast, Wing C. Chan, James O. Armitage
Journal: Journal of Clinical Oncology (2002)

PURPOSE: Hodgkin’s disease (HD) is a malignancy that displays a bimodal age distribution. Previous reports of treatment in patients ≥ 60 years have found a poor outcome, particularly in patients with advanced disease. Because of an improved side-effect profile, the regimen of chlorambucil, vinblastine, procarbazine, and prednisone (ChlVPP) has been proposed for use in elderly patients. PATIENTS AND METHODS: From September 1982 to May 1998, 262 patients with previously untreated HD received either ChlVPP (n = 176) or ChlVPP plus doxorubicin/bleomycin/vincristine (ChlVPP/ABV hybrid; n = 86). Fifty-six patients were ≥ 60 years old, and 206 were younger than 60 years. RESULTS: The 5-year overall survival (OS; 87% v 39%) and the 5-year event-free survival (EFS; 75% v 31%) favored patients younger than 60 years of age. Prognostic factors analyzed in patients ≥ 60 years of age, other than type of therapy, included sex, stage, Karnofsky performance score, lactic dehydrogenase, number of extranodal sites, B symptoms, size of largest mass, and histologic subtype. In patients older than 60 years, none of the clinical features was a statistically significant predictor of EFS; however, ChlVPP/ABV hybrid was associated with a decreased risk of an event (relative risk, 0.40; 95% confidence interval, 0.19 to 0.83; P = .014) compared with ChlVPP. The 5-year OS for patients ≥ 60 years who received ChlVPP was 30%, compared with 67% for those patients receiving the ChlVPP/ABV regimen ( P = .0086) CONCLUSION: Patients ≥ 60 years with HD who require chemotherapy are better treated with ChlVPP/ABV hybrid than with ChlVPP alone.
Massachusetts Medical Society
Authors: Mark Falcon Lesses
Journal: New England Journal of Medicine (1954)

HUMAN SERUM ALBUMIN AND PLASMA SALVAGEThe following statement on outdated blood is presented for the information of fellows of the Society:About 140,000 blood transfusions are given annually in Massachusetts hospitals, according to statistics gathered recently by the Massachusetts Medical Society's Committee for Supervision of the Red Cross Blood Program. This large amount of whole blood is obtained through activities of hospital blood banks and from the Red Cross by volunteer donations, each source providing about half the total. The Committee has also ascertained that the number of bloods collected by the hospital and Red Cross blood banks exceed . . .
Counting Calories
Authors: Mike Mitka
Journal: JAMA (2009)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Direct-acting antiviral treatment in patients infected with a non-epidemic hepatitis C genotype in the Netherlands: results from a nationwide cohort study
Authors: Cas Isfordink, Thijs van der Laar, Els Wessels, Richard Molenkamp, Marjolein Knoester, Bert Baak, Bart Van Hoek, Sylvia Brakenhoff, Hans Blokzijl, Marc van der Valk, Janke Schinkel
Journal: Journal of Hepatology (2020)
Superior Vena Cava Syndrome
Authors: Ken C. Davidson
Journal: JAMA (1975)

<h3>To the Editor.—</h3> I would respectfully like to take exception of a SPECIAL COMMUNICATION (231:58,1975) in which Drs. Lokich and Goodman, in discussion of the venous access procedures, raise the specter of an undue complication rate associated with attempts at venography in the evaluation of superior vena cava syndrome (SVCS). In light of my previous experience and discussion with others, I raise exception with the idea that venography is fraught with great difficulty and complication when performed judiciously and with care. Venographic techniques in this day and age involve the use of flexible, relatively atraumatic catheters, guide wires, and puncture techniques that need not result in increased thrombosis, phlebitis, bleeding, hematoma formation, or other of the complications that they mention. Simple percutaneous needle puncture of a peripheral vein, usually in the forearm or antecubital area, followed by the introduction of a smallgauge plastic catheter over a flexible guide wire under
Osleriana
Journal: JAMA (1986)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Progressive Medicine.
Journal: JAMA (1900)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
BROADCASTING BUNK
Journal: JAMA (1930)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
LEUCOCYTES AND OPSONINS IN THE DEFENSE OF THE BODY.
Journal: JAMA (1906)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Herpes zoster after splenectomy. A study of patients without malignancy
Authors: D. M. Manning
Journal: JAMA (1980)

Follow-up information was obtained on 102 unselected patients who had undergone splenectomy for nonmalignant disease (ie, trauma, surgical complications, and hematologic indications). In 422 postsplenectomy years, three cases of herpes zoster were observed, two of which were associated with generalized cutaneous dissemination. This incidence is no greater than that reported elsewhere for age-matched normal population. We conclude that in patients without malignancy, splenectomy does not predispose to herpes zoster, but may play a role in cutaneous dissemination. (<i>JAMA</i>243:56-58, 1980)
Successful removal of hematoma from internal capsule: 23-year follow-up
Authors: M. Scott
Journal: JAMA (1972)

<h3>To the Editor.—</h3> Spontaneous intracerebral hematomas in hypertensive patients occurring in areas other than the internal capsule have been removed surgically with low mortality and morbidity.<sup>1,2</sup>However, I agree with McKissock et al that statistically, in hypertensive patients with such hematomas in the internal capsule, the mortality following the operative or nonoperative treatment is high; approximately 60% for both groups, and the neurological deficit in the survivors is severe.<sup>3,4</sup> The following case is reported to show that there are exceptions to statistical guidelines; that each patient must be evaluated as an individual problem and "a one hundred percent statistic unto himself"; and that surgical intervention in some hypertensive patients can be life saving and result in a long, livable life. This patient's clinical course also suggests that hypertensive cerebrovascular disease beginning at an early age can persist for many years after the removal of an intracerebral hematoma without