tbuckley/cabot-search huggingface dataset:
Quantified integrated hepatitis B virus is related to viral activity in patients with chronic hepatitis B
Authors: Robin Erken, Vladimir Loukachov, Karel van Dort, Anne van den Hurk, R. Bart Takkenberg, Anniki de Niet, Louis Jansen, Sophie Willemse, Henk Reesink, Neeltje Kootstra
Journal: Hepatology (2022)

Abstract Background and Aims HBV can integrate in the host genome of the hepatocyte and recent findings suggest that integrated HBV contributes to the persistent production of viral proteins. Here, we quantified the levels of integrated HBV in patients with chronic hepatitis B (CHB) and analyzed the relation between HBV integration, virological activity (plasma HBV DNA and HBsAg levels), and clinical outcomes. Approach and Results We developed and validated a multistep Arthrobacter luteus (Alu)‐PCR that specifically amplifies integrated HBV and RT‐Alu‐PCR detecting mRNA transcripts derived from integrated HBV. Pretreatment liver biopsy samples and baseline characteristics of 124 patients with CHB either treated for 48 weeks with pegylated interferon plus adefovir or tenofovir or receiving no treatment were available for analysis. Integrated HBV sequences containing open reading frame S and X (but not C) and S and X mRNA transcripts derived from integrated HBV could be detected and quantified in liver biopsies. Integrated HBV levels correlated with HBV DNA, HBsAg, alanine aminotransferase plasma levels, and the liver histology activity index but not to levels of intrahepatic covalently closed circular DNA (cccDNA), plasma pregenomic RNA, or hepatitis B core‐related antigen. Multivariable logistic regression analysis showed that lower baseline HBV integration levels were independently associated with HBsAg loss (functional cure) within 5 years follow‐up. Conclusions Integrated HBV levels are strongly correlated with surrogate markers for virological activity but not to cccDNA levels and are predictive for HBsAg loss. Our data suggest that integrated HBV is closely related to HBV replication and may therefore be an important tool in the evaluation and development of treatment modalities aiming to cure CHB.
Association of Essential Tremor With Novel Risk Loci
Authors: Calwing Liao, Charles-Etienne Castonguay, Karl Heilbron, Veikko Vuokila, Miranda Medeiros, Gabrielle Houle, Fulya Akçimen, Jay P. Ross, Helene Catoire, Monica Diez-Fairen, Jooeun Kang, Stefanie H. Mueller, Simon L. Girard, Franziska Hopfner, Delia Lorenz, Lorraine N. Clark, Alexandra I. Soto-Beasley, Stephan Klebe, Mark Hallett, Zbigniew K. Wszolek, Manuela Pendziwiat, Oswaldo Lorenzo-Betancor, Klaus Seppi, Daniela Berg, Carles Vilariño-Güell, Ronald B. Postuma, Geneviève Bernard, Nicolas Dupré, Joseph Jankovic, Claudia M. Testa, Owen A. Ross, Thomas Arzberger, Sylvain Chouinard, Elan D. Louis, Paola Mandich, Carmine Vitale, Paolo Barone, Elena García-Martín, Hortensia Alonso-Navarro, José A. G. Agúndez, Félix Javier Jiménez-Jiménez, Pau Pastor, Alex Rajput, Günther Deuschl, Gregor Kuhlenbaümer, Inge A. Meijer, Patrick A. Dion, Guy A. Rouleau
Journal: JAMA Neurology (2022)

<h3>Importance</h3> Essential tremor (ET) is one of the most common movement disorders, affecting 5% of the general population older than 65 years. Common variants are thought to contribute toward susceptibility to ET, but no variants have been robustly identified. <h3>Objective</h3> To identify common genetic factors associated with risk of ET. <h3>Design, Setting, and Participants</h3> Case-control genome-wide association study. Inverse-variance meta-analysis was used to combine cohorts. Multicenter samples collected from European populations were collected from January 2010 to September 2019 as part of an ongoing study. Included patients were clinically diagnosed with or reported having ET. Control individuals were not diagnosed with or reported to have ET. Of 485 250 individuals, data for 483 054 passed data quality control and were used. <h3>Main Outcomes and Measures</h3> Genotypes of common variants associated with risk of ET. <h3>Results</h3> Of the 483 054 individuals included, there were 7177 with ET (3693 [51.46%] female; mean [SD] age, 62.66 [15.12] years), and 475 877 control individuals (253 785 [53.33%] female; mean [SD] age, 56.40 [17.6] years). Five independent genome-wide significant loci and were identified and were associated with approximately 18% of ET heritability. Functional analyses found significant enrichment in the cerebellar hemisphere, cerebellum, and axonogenesis pathways. Genetic correlation (<i>r</i>), which measures the degree of genetic overlap, revealed significant common variant overlap with Parkinson disease (<i>r</i>, 0.28;<i>P</i> = 2.38 × 10<sup>−8</sup>) and depression (<i>r</i>, 0.12;<i>P</i> = 9.78 × 10<sup>−4</sup>). A separate fine-mapping of transcriptome-wide association hits identified genes such as<i>BACE2</i>,<i>LRRN2</i>,<i>DHRS13</i>, and<i>LINC00323</i>in disease-relevant brain regions, such as the cerebellum. <h3>Conclusions and Relevance</h3> The results of this genome-wide association study suggest that a portion of ET heritability can be explained by common genetic variation and can help identify new common genetic risk factors for ET.
High-resolution micro-ultrasound for local staging of prostate cancer: A prospective single-center experience
Authors: V. Fasulo, F. Regis, M. Paciotti, F. Persico, D. Maffei, A. Saita, A. Uleri, R. Hurle, P. Casale, M. Lazzeri, G. Guazzoni, N. Buffi, G. Lughezzani
Journal: European Urology (2021)
Hybrid, ultra-deep metagenomic sequencing enables genomic and functional characterization of low-abundance species in the human gut microbiome
Authors: Hao Jin, Lijun You, Feiyan Zhao, Shenghui Li, Teng Ma, Lai-Yu Kwok, Haiyan Xu, Zhihong Sun
Journal: Gut Microbes (2022)

A large number of microbial genomes have already been identified from the human gut microbiome, but the understanding of the role of the low-abundance species at the individual level remains challenging, largely due to the relatively shallow sequencing depth used in most studies. To improve genome assembling performance, a HiSeq-PacBio hybrid, ultra-deep metagenomic sequencing approach was used to reconstruct metagenomic-assembled genomes (MAGs) from 12 fecal samples. Such approach combined third-generation sequencing with ultra-deep second-generation sequencing to improve the sequencing coverage of the low-abundance subpopulation in the gut microbiome. Our study generated a total of 44 megabase-scale scaffolds, achieving four single-scaffolds of complete (circularized, no gaps) MAGs (CMAGs) that were the first circular genomes of their species. Moreover, 475 high-quality MAGs were assembled across all samples. Among them, 234 MAGs were currently uncultured, including 24 MAGs that were not found in any public genome database. Additionally, 287 and 77 MAGs were classified as low-abundance (0.1–1%) and extra-low-abundance (<0.1%) gut species in each individual, respectively. Our results also revealed individual-specific genomic features in the MAG profiles, including microbial genome growth rate, selective pressure, and frequency of chromosomal mobile genetic elements. Finally, thousands of extrachromosomal mobile genetic elements were identified from the metagenomic data, including 5097 bacteriophages and 79 novel plasmid genomes. Overall, our strategy represents an important step toward comprehensive genomic and functional characterization of the human gut microbiome at an individual level.
Prospective study of the relationship between clinical outcomes of enzalutamide and serum androgen levels measured by LC-MS/MS in CRPC patients
Authors: Y. Miyazawa, D. Oka, H. Nakayama, T. Miyao, T. Nakamura, Y. Takezawa, N. Shimizu, Y. Matsuo, O. Haruyuki, T. Takei, Y. Sekine, S. Arai, K. Suzuki
Journal: European Urology (2021)
Erratum for the Research Article: “The <i>Uppsala APP</i> deletion causes early onset autosomal dominant Alzheimer’s disease by altering APP processing and increasing amyloid β fibril formation” by M. Pagnon de la Vega, V. Giedraitis, W. Michno, L. Kilander, G. Güner, M. Zielinski, M. Löwenmark, R. Brundin, T. Danfors, L. Söderberg, I. Alafuzoff, L. N. Nilsson, A. Erlandsson, D. Willbold, S. A. Müller, G. F. Schröder, J. Hanrieder, S. F. Lichtenthaler, L. Lannfelt, D. Sehlin, M. Ingelsson
Journal: Science Translational Medicine (2022)

[Figure: see text].
Sleep disturbances during the COVID-19 pandemic: A systematic review, meta-analysis, and meta-regression
Authors: Haitham A. Jahrami, Omar A. Alhaj, Ali M. Humood, Ahmad F. Alenezi, Feten Fekih-Romdhane, Maha M. AlRasheed, Zahra Q. Saif, Nicola Luigi Bragazzi, Seithikurippu R. Pandi-Perumal, Ahmed S. BaHammam, Michael V. Vitiello
Journal: Sleep Medicine Reviews (2022)
3D printed biomimetic epithelium/stroma bilayer hydrogel implant for corneal regeneration
Authors: Binbin He, Jie Wang, Mengtian Xie, Miaoyi Xu, Yahan Zhang, Huijie Hao, Xiaoli Xing, William Lu, Quanhong Han, Wenguang Liu
Journal: Bioactive Materials (2022)

Corneal regeneration has always been a challenge due to its sophisticated structure and undesirable keratocyte-fibroblast transformation. Herein, we propose 3D printing of a biomimetic epithelium/stroma bilayer implant for corneal regeneration. Gelatin methacrylate (GelMA) and long-chain poly(ethylene glycol) diacrylate (PEGDA) are blended to form a two-component ink, which can be printed to different mechanically robust programmed PEGDA-GelMA objects by Digital Light Processing (DLP) printing technology, due to the toughening effect of crystalline crosslinks from long-chain PEGDA on GelMA hydrogel after photo-initiated copolymerization. The printed PEGDA-GelMA hydrogels support cell adhesion, proliferation, migration, meanwhile demonstrating a high light transmittance, and an appropriate swelling degree, nutrient permeation and degradation rate. A bi-layer dome-shaped corneal scaffold consisting of rabbit corneal epithelial cells (rCECs)-laden epithelia layer and rabbit adipose-derived mesenchymal stem cells (rASCs)-laden orthogonally aligned fibrous stroma layer can be printed out with a high fidelity and robustly surgical handling ability. This bi-layer cells-laden corneal scaffold is applied in a rabbit keratoplasty model. The post-operative outcome reveals efficient sealing of corneal defects, re-epithelialization and stromal regeneration. The concerted effects of microstructure of 3D printed corneal scaffold and precisely located cells in epithelia and stroma layer provide an optimal topographical and biological microenvironment for corneal regeneration.
Risk factors for postoperative wound dehiscence after skin repair: A case-control study
Authors: Murad Alam, Vishnu Harikumar, Kelly A. Reynolds, Derek Y. Hsu, Jake M. Lazaroff, Brian R. Chen, Ketan Jain-Poster, Eran C. Gwillim, Sarah Ibrahim, Bianca Y. Kang, Nancy L. Cho, Mario M. Leitao, John Y. Kim, Rachel E. Christensen, Emily Poon, Beatrice Nardone
Journal: Journal of the American Academy of Dermatology (2022)
Clinical reliability of genomic data obtained from spinal metastatic tumor samples
Authors: Ori Barzilai, Axel Martin, Anne S Reiner, Ilya Laufer, Adam Schmitt, Mark H Bilsky
Journal: Neuro-Oncology (2022)

Abstract Background The role of tumor genomic profiling is rapidly growing as it results in targeted, personalized, cancer therapy. Though routinely used in clinical practice, there are no data exploring the reliability of genomic data obtained from spine metastases samples often leading to multiple biopsies in clinical practice. This study compares the genomic tumor landscape between spinal metastases and the corresponding primary tumors as well as between spinal metastases and visceral metastases. Methods Spine tumor samples, obtained for routine clinical care from 2013 to 2019, were analyzed using MSK-IMPACT, a next-generation sequencing assay. These samples were matched to primary or metastatic tumors from the corresponding patients. A concordance rate for genomic alterations was calculated for matching sample pairs within patients for the primary and spinal metastatic tumor samples as well as for the matching sample pairs within patients for the spinal and visceral metastases. For a more robust and clinically relevant estimate of concordance, subgroup analyses of previously established driver mutations specific to the main primary tumor histologies were performed. Results Eighty-four patients contributed next-generation sequencing data from a spinal metastasis and at least one other site of disease: 54 from the primary tumor, 39 had genomic tumor data from another, nonspinal metastasis, 12 patients participated in both subsets. For the cohort of matched primary tumors and spinal metastases (n = 54) comprised of mixed histologies, we found an average concordance rate of 96.97% for all genetic events, 97.17% for mutations, 100% for fusions, 89.81% for deletions, and 97.01% for amplifications across all matched samples. Notably, &amp;gt;25% of patients harbored at least one genetic variant between samples tested, though not specifically for known driver mutations. The average concordance rate of driver mutations was 96.99% for prostate cancer, 95.69% (P = .0004513) for lung cancer, and 96.43% for breast cancer. An average concordance of 99.02% was calculated for all genetic events between spine metastases and non-spinal metastases (n = 41) and, more specifically, a concordance rate of 98.91% was calculated between spine metastases and liver metastases (n = 12) which was the largest represented group of nonspine metastases. Conclusion Sequencing data performed on spine tumor samples demonstrate a high concordance rate for genetic alterations between the primary tumor and spinal metastasis as well as between spinal metastases and other, visceral metastases, particularly for driver mutations. Spine tumor samples may be reliably used for genomic-based decision making in cancer care, particularly for prostate, NSCLC, and breast cancer.
Corrigendum to “Seroprevalence of SARS-CoV-2 in 1922 blood donors from the Lodi Red Zone and adjacent Lodi metropolitan and suburban area” [Clin Microbiol Infect 27 (6) (2021 Jun) 914.e1-914.e4]
Authors: Irene Cassaniti, Elena Percivalle, Antonella Sarasini, Giuseppe Cambiè, Edoardo Vecchio Nepita, Roberta Maserati, Alessandro Ferrari, Alfonso Corcione, Raffaella Di Martino, Alice Bonetti, Annapia Di Napoli, Guglielmo Ferrari, Fausto Baldanti
Journal: Clinical Microbiology and Infection (2022)
A PARTHENOGENESIS allele from apomictic dandelion can induce egg cell division without fertilization in lettuce
Authors: Charles J. Underwood, Kitty Vijverberg, Diana Rigola, Shunsuke Okamoto, Carla Oplaat, Rik H. M. Op den Camp, Tatyana Radoeva, Stephen E. Schauer, Joke Fierens, Kim Jansen, Sandra Mansveld, Marco Busscher, Wei Xiong, Erwin Datema, Koen Nijbroek, Evert-Jan Blom, Ross Bicknell, Andrew Catanach, Sylvia Erasmuson, Christopher Winefield, Arjen J. van Tunen, Marcel Prins, M. Eric Schranz, Peter J. van Dijk
Journal: Nature Genetics (2022)
Global Representation During a Global Pandemic
Authors: Ethwako Mlia-Phiri, Samantha Lissauer, Jill E. Weatherhead
Journal: JAMA Pediatrics (2022)

Jean B. Nachega, MD, PhD, MPH; Nadia A. Sam-Agudu, MD; Rhoderick N. Machekano, PhD, MPH; Helena Rabie, MBChB, PhD; Marieke M. van der Zalm, MBChB, PhD; Andrew Redfern, MBChB, MPhil; Angela Dramowski, MBChB, PhD; Natasha O'Connell, MBChB, MMed; Michel Tshiasuma Pipo, MD; Marc B. Tshilanda, MD; Liliane Nsuli Byamungu, MD, MSc; Refiloe Masekela, MBChB, PhD; Prakash Mohan Jeena, MBChB, PhD; Ashendri Pillay, MBChB; Onesmus W. Gachuno, MBChB, MMED; John Kinuthia, MBChB, MMED, MPH; Daniel Katuashi Ishoso, MD; Emmanuella Amoako, MBChB; Elizabeth Agyare, MBChB; Evans K. Agbeno, MBChB, MPH; Charles Martyn-Dickens, MBChB; Justice Sylverken, MD; Anthony Enimil, MBChB; Aishatu Mohammed Jibril, MBBS; Asara M. Abdullahi, MBBS; Oma Amadi, MBBS; Umar Mohammed Umar, MD; Lovemore Nyasha Sigwadhi, MSc; Michel P. Hermans, MD, PhD; John Otshudiema Otokoye, MD, MPH; Placide Mbala-Kingebeni, MD, PhD; Jean-Jacques Muyembe-Tamfum, MD, PhD; Alimuddin Zumla, MD, PhD; Nelson K. Sewankambo, MD; Hellen Tukamuhebwa Aanyu, MBChB; Philippa Musoke, MBChB, PhD; Fatima Suleman, BPharm, PhD; Prisca Adejumo, RN, PhD; Emilia V. Noormahomed, MD, PhD; Richard J. Deckelbaum, MD; Mary Glenn Fowler, MD; Léon Tshilolo, MD, PhD; Gerald Smith, MSc; Edward J. Mills, PhD, MSc; Lawal W. Umar, MBBS; Mark J. Siedner, MD; Mariana Kruger, MMed, MPhil, PhD; Philip J. Rosenthal, MD; John W. Mellors, MD; Lynne M. Mofenson, MD; African Forum for Research and Education in Health (AFREhealth) COVID-19 Research Collaboration on Children and Adolescents; Jean B. Nachega; Nadia A. Sam-Agudu; Rhoderick N. Machekano; Helena Rabie; Marieke M. Van der Zalm; Andrew Redfern; Angela Dramowski; Natasha O'Connell; Michel T. Pipo; Marc B. Tshilanda; Liliane N. Byamungu; Refiloe Masekela; Prakash M. Jeena; Ashendri Pillay; Onesmus W. Gachuno; John Kinuthia; Daniel K. Ishoso; Emmanuela Amoako; Elizabeth Agyare; Evans K. Agbeno; Charles Martyn-Dickens; Justice Sylverken; Anthony Enimil; Aishatu M. Jibril; Asara M. Abdullahi; Oma Amadi; Umar M. Umar; Lovemore N. Sigwadhi; Michel P. Hermans; John O. Otokoye; Placide Mbala-Kingebeni; Alimuddin Zumla; Hellen T. Aanyu; Philippa Musoke; Fatima Suleman; Emilia V. Noormahomed; Mary G. Fowler; Leon Tshilolo; Mariana Kruger; Gerald Smith; Philip J. Rosenthal; Edward J. Mills; Lawal W. Umar; John W. Mellors; Prisca Adejumo; Nelson K. Sewankambo; Mark J. Siedner; Richard J. Deckelbaum; Jean-Jacques Muyembe-Tamfum; Lynne M. Mofenson; Nancy Mongweli; Peter S. Nyasulu ; Joule Madinga; Christian Bongo-Pasi Nswe; Jean-Marie N. Kayembe; Abdon Mukalay; Alfred Mteta; Aster Tsegaye; Don Jethro M. Landu; Serge Zigabe; Ameena Goga; Rodney Ehrlich; Andre P. Kengne; John L. Johnson; Peter Kilmarx; Birhanu Ayele; Ireneous N. Dasoberi; Clara Sam-Woode; Georgina Yeboah; Chibueze Adirieje
The Gut Microbiome of Adults With Type 1 Diabetes and Its Association With the Host Glycemic Control
Authors: Smadar Shilo, Anastasia Godneva, Marianna Rachmiel, Tal Korem, Yuval Bussi, Dmitry Kolobkov, Tal Karady, Noam Bar, Bat Chen Wolf, Yitav Glantz-Gashai, Michal Cohen, Nehama Zuckerman Levin, Naim Shehadeh, Noah Gruber, Neriya Levran, Shlomit Koren, Adina Weinberger, Orit Pinhas-Hamiel, Eran Segal
Journal: Diabetes Care (2022)

OBJECTIVE Previous studies have demonstrated an association between gut microbiota composition and type 1 diabetes (T1D) pathogenesis. However, little is known about the composition and function of the gut microbiome in adults with longstanding T1D or its association with host glycemic control. RESEARCH DESIGN AND METHODS We performed a metagenomic analysis of the gut microbiome obtained from fecal samples of 74 adults with T1D, 14.6 ± 9.6 years following diagnosis, and compared their microbial composition and function to 296 age-matched healthy control subjects (1:4 ratio). We further analyzed the association between microbial taxa and indices of glycemic control derived from continuous glucose monitoring measurements and blood tests and constructed a prediction model that solely takes microbiome features as input to evaluate the discriminative power of microbial composition for distinguishing individuals with T1D from control subjects. RESULTS Adults with T1D had a distinct microbial signature that separated them from control subjects when using prediction algorithms on held-out subjects (area under the receiver operating characteristic curve = 0.89 ± 0.03). Linear discriminant analysis showed several bacterial species with significantly higher scores in T1D, including Prevotella copri and Eubacterium siraeum, and species with higher scores in control subjects, including Firmicutes bacterium and Faecalibacterium prausnitzii (P &amp;lt; 0.05, false discovery rate corrected for all). On the functional level, several metabolic pathways were significantly lower in adults with T1D. Several bacterial taxa and metabolic pathways were associated with the host’s glycemic control. CONCLUSIONS We identified a distinct gut microbial signature in adults with longstanding T1D and associations between microbial taxa, metabolic pathways, and glycemic control indices. Additional mechanistic studies are needed to identify the role of these bacteria for potential therapeutic strategies.
Autologous tunica albuginea cells in fibrin scaffold for correction of penile chordee: An experimental study in rabbits
Authors: M. Abdullateef, T.E. Helmy, A.T. Hafez, M. Gabr, H.G. Amer, N. Barakat, M. Abdelhamid, M. Bazeed
Journal: European Urology (2021)
Patient‐reported outcomes in HCC: A scoping review by the Practice Metrics Committee of the American Association for the Study of Liver Diseases
Authors: Marina Serper, Neehar D. Parikh, Grace Thiele, Nadia Ovchinsky, Shivang Mehta, Alexander Kuo, Chanda Ho, Fasiha Kanwal, Michael Volk, Sumeet K. Asrani, Marwan S. Ghabril, John R. Lake, Raphael B. Merriman, Timothy R. Morgan, Elliot B. Tapper
Journal: Hepatology (2022)

HCC is a leading cause of mortality in patients with advanced liver disease and is associated with significant morbidity. Despite multiple available curative and palliative treatments, there is a lack of systematic evaluation of patient-reported outcomes (PROs) in HCC.The American Association for the Study of Liver Diseases Practice Metrics Committee conducted a scoping review of PROs in HCC from 1990 to 2021 to (1) synthesize the evidence on PROs in HCC and (2) provide recommendations on incorporating PROs into clinical practice and quality improvement efforts. A total of 63 studies met inclusion criteria investigating factors associated with PROs, the relationship between PROs and survival, and associations between HCC therapy and PROs. Studies recruited heterogeneous populations, and most were cross-sectional. Poor PROs were associated with worse prognosis after adjusting for clinical factors and with more advanced disease stage, although some studies showed better PROs in patients with HCC compared to those with cirrhosis. Locoregional and systemic therapies were generally associated with a high symptom burden; however, some studies showed lower symptom burden for transarterial radiotherapy and radiation therapy. Qualitative studies identified additional symptoms not routinely assessed with structured questionnaires. Gaps in the literature include lack of integration of PROs into clinical care to guide HCC treatment decisions, unknown impact of HCC on caregivers, and the effect of palliative or supportive care quality of life and health outcomes.Evidence supports assessment of PROs in HCC; however, clinical implementation and the impact of PRO measurement on quality of care and longitudinal outcomes need future investigation.
Deep immune phenotyping reveals similarities between aging, Down syndrome, and autoimmunity
Authors: Katharina Lambert, Keagan G. Moo, Azlann Arnett, Gautam Goel, Alex Hu, Kaitlin J. Flynn, Cate Speake, Alice E. Wiedeman, Vivian H. Gersuk, Peter S. Linsley, Carla J. Greenbaum, S. Alice Long, Rebecca Partridge, Jane H. Buckner, Bernard Khor
Journal: Science Translational Medicine (2022)

Permutational analysis of the immune system reveals advanced immune aging in individuals with Down syndrome and in individuals with type 1 diabetes.
Comment on Ipp and Kumar. A Clinical Conundrum: Intensifying Glucose Control in the Presence of Advanced Diabetic Retinopathy. Diabetes Care 2021;44:2192–2193
Authors: Vincent Rigalleau, Alice Larroumet, Kamel Mohammedi, Laurence Baillet-Blanco, Marie Monlun, Marie-Noelle Delyfer, Jean-François Korobelnik, Ninon Foussard
Journal: Diabetes Care (2022)
The use of augmented reality to guide intraoperative frozen section during robot-assisted radical prostatectomy
Authors: R. Schiavina, L. Bianchi, F. Chessa, A. Angiolini, L. Cercenelli, B. Bortolani, E. Molinaroli, C. Casablanca, C. Gaudiano, A. Porreca, R. Golfieri, D. Romagnoli, F. Giunchi, M. Fiorentino, S. Puliatti, A. Mottrie, S. Diciotti, E. Marcelli, E. Brunocilla
Journal: European Urology (2021)