tbuckley/cabot-search huggingface dataset:
Civil war reenactors revere, learn from the past
Authors: T. B. Cole
Journal: JAMA (1996)

AT THE THIRD Annual Convocation of the Society of Civil War Surgeons, held last month in Harper's Ferry, WVa, reenactors and historians met to consider not only what happened during the war but how and why it happened that way. Rather than sail, fly fish, or pursue some more usual avocation, these men and women (not all of them physicians) devote themselves to reenacting as authentically as possible or studying intently the events of those four awful years. James Ellison, for example, assumes the role of a medical officer in the 33rd Virginia Regiment, Stonewall Brigade, to provide some context for the popular image of the Civil War surgeon. "We were bloody surgeons, yes, but forget Hollywood. Think why." He explains: Before every battle, the surgical team would take the smoothest, most solid wooden door they could find off its hinges and lay it across two supports. They might cover
Officers and members of the House of Delegates of the American Medical Association
Journal: JAMA (1984)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Organe mit innerer Sekretion: Kurzgefasstes Lehrbuch der Endokrinologie für Studierende und Ärzte.
Journal: JAMA (1953)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Spurious Leukocytosis and Thrombocytopenia
Authors: Dilip L. Solanki
Journal: JAMA (1983)

Three patients with spurious thrombocytopenia caused by in vitro clumping of platelets also had leukocytosis that was inappropriate for their clinical state and could not be verified on examination of a blood smear. Serial blood counts and analysis of the platelet and WBC histograms proved the "leukocytosis" to be spurious and caused by platelet clumps erroneously "recognized" by the counter as white blood cells. In three additional patients, the WBC counts increased concomitantly with a decrease in their platelet counts but remained within the normal range. Abnormal platelet and WBC counts generated by automated cell counters must be verified by examination of a blood smear before patients are subjected to unwarranted investigations and therapy. (<i>JAMA</i>1983;250:2514-2515)
Polymeric coating lubricates nanocontainers to escape macrophage uptake for bioreceptor recognition
Authors: Yulong Sun, Yanxin Han, Yannong Dou, Xinqi Gong, Haimang Wang, Xiaoyu Yu, Qiang Wang, Yixin Wang, Yue Dai, Fangfu Ye, Wei Jin, Hongyu Zhang
Journal: Bioactive Materials (2022)

Accurate drug delivery to the lesion has been deliberated for several decades, but one important phenomenon is usually neglected that the immune system can prevent smooth transportation of nanomedicine. Although injection would reduce first-pass effect, macrophages in the blood can still recognize and phagocytose nanomedicine. Here we show that a lubricated nanocontainer, which is prepared based on polyelectrolytes and mesoporous silica nanoparticles, can accurately target muscarinic bioreceptor while escaping from the identification of macrophages. Through in vitro and in vivo studies, this nanocontainer, combining both immune escape and bioreceptor targeting, has greatly improved the drug bioavailability. Additionally, this nanocontainer shows good biocompatibility, and the targeted heart tissues and other important metabolic organs, such as liver and kidney, keep physiological structures and functions without the detection of side effects. Furthermore, the mechanism of immune escape for the developed nanocontainer has been investigated by lubrication test and molecular simulation. We anticipate that our study will establish a new perspective on the achievement of immune escape-based targeted drug delivery, which can provide a fundamental approach for the design of related biomaterials.
Correction
Journal: BMJ (1954)

the provision to all patients of many necessary but expensive drugs without payment (in particular those drugs for which, because of their cost, dispensing doctors receive payment over and above their capitation fees).Ideally, perhaps, these drugs alone could be supplied on a standard tariff, preserving the art of dispensing for medicines of less pro- hibitive cost.-Iam, etc., Meriden, near Coventry.
Comparison of MRI, TEE and invasive measurement for evaluation of atrial septal defects type II before and after transcatheter closure Thorsten Dill, Anna John, Thomas Neumann, Roland Brandt, Matthias Rau, Georg Bachmann, Wolfgang Ricken, Christian W. Hamm. Kerckhoff Clinic, Bad Nauheim, Germany
Journal: Journal of the American College of Cardiology (2001)
Abstract P302: Ethnic Difference of Cardiorespiratory Fitness and Related to Factors in Young Adults: The Nhanes 1999-2004
Authors: Hong Seok LEE, Zhiwei Zhang, Karen Xu, Yong-Moon Park
Journal: Circulation (2018)

Background: Cardiorespiratory fitness is a distinct health characteristic that relates to the ability to perform physical activity. Higher cardiorespiratory fitness was reported to have reverse relationship with overall mortality and morbidity rates due to various chronic disease. The assessment of cardiorespiratory fitness was measured by maximal oxygen uptake (VO2max; mL/kg/minute) on a submaximal treadmill test. This study was aimed to examine cardiorespiratory fitness among U.S. adults 20-49 years of age, to describe the distribution of cardiorespiratory fitness and cardiovascular risk factors depends on different ethnicity for without physical limitations or indications of cardiovascular disease. Method: Data from the 1999-2004, National Health and Nutrition Examination Survey were used to describe the distribution of cardiorespiratory fitness for adults 20-49 years of age. 8324 out of 31126 subjects have valid values of cardiopulmonary fitness in the dataset with 5391 in low category of cardiorespiratory fitness (VO 2 max &lt; 27), 2606 in medium category (37.1 &gt; VO 2 max ≥27) and 327 in high category (37.1 ≥ VO 2 max). The risk factors for cardiopulmonary fitness was assessed by using logistic regression after adjusting all cardiovascular risk factors. All data were analyzed using SAS Ver. 9.4. Result: Overall, there is no significant association of cardiorespiratory fitness with ethnicity ( P =0.08). 65.9% of study population was male in all races. Among, non-Hispanic whites, those with 25 m 2 /kg &gt; BMI had better cardiorespiratory fitness (more than 37.1 mL/kg/minute) than those with BMI ≥ 35 [Odds ratio (OR): 0.496, Confidence Interval (CI): 0.258-0.957]. A similar pattern was observed for Mexican Americans. Non-Hispanic black with 25 m 2 /kg &gt; BMI had better cardiorespiratory fitness than ones with BMI ≥ 35 m 2 /kg [OR:0.137, CI:0.059-0.318], 35 m 2 /kg &gt; BMI≥30 m 2 /kg [OR:0.269, CI:0.124-0.583], 30 m 2 /kg &gt; BMI≥25 m 2 /kg [OR: 0.241,0.123-0.318]. Non-Hispanic white with higher diastolic blood pressure over 90 mmHg had tendency to have lower cardiorespiratory fitness. Among metabolic panel, only Mexican American with LDL&lt;100 mg/dl has higher cardiorespiratory fitness [OR:0.559, CI:0.319-0.981]. Discussion: Our findings on cardiorespiratory fitness level among non-Hispanic blacks, non-Hispanic whites and Mexican Americans are similar to previously reported studies, however, non-Hispanic black had different risk factors related to cardiorespiratory fitness, especially significant benefit from lower BMI less than 25 m 2 /kg since other ethnicities with BMI less than 25 m 2 /kg had benefit only compared to BMI&gt; 35 m 2 /kg. These results can be used to improve cardiorespiratory fitness level for future population based on ethnicities. The different risk factors in fitness status can also be used to develop health policies and targeted educational campaigns.
Growth and Development with Special Reference to Domestic Animals. XV: Energy and Nitrogen Metabolism During the First Year of Postnatal Life. University of Missouri, College of Agriculture, Agricultural Experiment Station, Research Bulletin 143.
Journal: JAMA (1931)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract P088: Trends in Serum Lipids in US Youth Ages 6 to 19 Years: National Health and Nutrition Examination Survey 2003 to 2014
Authors: Amanda M Perak, Hongyan Ning, Linda V Van Horn, Sarah D de Ferranti, Donald M Lloyd-Jones
Journal: Circulation (2018)

Introduction: Between 1988-94 and 2007-10, total cholesterol (TC), non-HDL-C, HDL-C, LDL-C, and triglycerides (TG) showed favorable trends in US youth. We tested the hypotheses that these favorable trends continued in the more recent period 2003-14 and that favorable trends were also seen in apolipoprotein B (apoB). Methods: We analyzed cross-sectional data in 15,712 youths aged 6-19 years from 6 NHANES surveys: 2003-04, 2005-06, 2007-08, 2009-10, 2011-12, and 2013-14. We applied survey weights to generate US population-level estimates and used multivariate linear regression to test for time-dependent trends in lipid levels, separately by sex and age group (6-11 vs. 12-19 years). Fasting LDL-C, TG and apoB were available only at ages ≥12 years; pubertal stage was not available. Results: See Figure. TC and non-HDL-C generally showed significant decreasing linear trends in mean levels and favorable linear trends in the prevalence of ideal versus adverse levels, but these improvements were smaller and not significant in 12-19 year-old females. Conversely, HDL-C generally showed an unfavorable downward trend over time, a finding that reached borderline significance in 12-19 year-old females (β=-0.3 mg/dL per year, p=0.054), and the prevalence of HDL-C &lt;40 mg/dL increased significantly in this group (β=0.6%, p=0.02). Despite the unfavorable HDL-C trend, TG showed significant favorable linear trends in mean levels and patterns of ideal versus adverse levels in both male and female 12-19 year-olds. LDL-C and apoB showed neutral to favorable patterns, with significant linear trends for an increase in the prevalence of LDL-C&lt;110 mg/dL (β=0.5%, p=0.02) and a decrease in the prevalence of apoB ≥110 mg/dL (β=-0.9%, p=0.03) for 12-19 year-old females. Conclusions: Favorable trends in lipids were generally seen in US youth from 2003-14, with a notable exception for HDL-C. It will be important to understand factors contributing to these trends.
The number sense represents (rational) numbers
Authors: Sam Clarke, Jacob Beck
Journal: Behavioral and Brain Sciences (2021)

On a now orthodox view, humans and many other animals possess a "number sense," or approximate number system (ANS), that represents number. Recently, this orthodox view has been subject to numerous critiques that question whether the ANS genuinely represents number. We distinguish three lines of critique - the arguments from congruency, confounds, and imprecision - and show that none succeed. We then provide positive reasons to think that the ANS genuinely represents numbers, and not just non-numerical confounds or exotic substitutes for number, such as "numerosities" or "quanticals," as critics propose. In so doing, we raise a neglected question: numbers of what kind? Proponents of the orthodox view have been remarkably coy on this issue. But this is unsatisfactory since the predictions of the orthodox view, including the situations in which the ANS is expected to succeed or fail, turn on the kind(s) of number being represented. In response, we propose that the ANS represents not only natural numbers (e.g., 7), but also non-natural rational numbers (e.g., 3.5). It does not represent irrational numbers (e.g., √2), however, and thereby fails to represent the real numbers more generally. This distances our proposal from existing conjectures, refines our understanding of the ANS, and paves the way for future research.
Paraguay Tea
Authors: T. C. Charles
Journal: BMJ (1890)

theritic bacilli, as many as five or six micro-organisms being sometimes enclosed within one cell.Some of these intracellular bacilli appear to be perfectly healthy, staining and retaining aniline colouring matters well, whilst other micro-organisms, also contained in ameeboid cells, show signs of degeneration varying from a mere difference in the power of retaining gentian violet, to complete disorganisation and destruction.The description of these changes I must reserve for another occasion.Many ameeboid cells in the membrane, more especially those present in its most superficial part, show distinct necrotic changes, many of them losing the power of retaining colouring matter.The nucleus breaks up, does not stain at all even with strong log wood or carmine, the surrounding protoplasm swelling up, becoming more yellow, and not unfrequently vacuolated.In
Re: Marc-Oliver Grimm, Antione G. van der Heijden, Marc Colombel, et al. Non–muscle-invasive Bladder Carcinoma by Standard Number and Dose of BCG Instillations Versus Reduced Number and Standard Dose of BCG Instillations: Results of the European Association of Urology Research Foundation Randomised Phase III Clinical Trial “NIMBUS”. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2020.04.066
Authors: Emre Karabay, İlker Tınay
Journal: European Urology (2020)
Covid-19: Intensive care units asked to take extra patients as hospitals struggle to find beds
Authors: Ingrid Torjesen
Journal: BMJ (2022)

Covid-19: Intensive care units asked to take extra patients as hospitals struggle to find beds Ingrid TorjesenPressure for general hospital beds is delaying the discharge of patients from intensive care units (ICUs), say consultants in intensive care.Some ICUs are even being asked to take patients who do not need high dependency support.
Books Received
Journal: JAMA (1910)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Reduction in aortic plaque burden in patients with familial hyperlipidemia as assessed by transesophageal echocardiography Susan D. Tiukinhoy, Neil J. Stone, Peter C. Dau, Bonnie J. Kane, Mark G. Rabbat, Noam Belkind, David D. McPherson. Northwestern University Medical School, Chicago &amp; Evanston, IL
Journal: Journal of the American College of Cardiology (2001)
The effects of tirofiban versus abciximab among diabetic patients undergoing stent placement: The TARGET trial David J. Moliterno, Howard C. Herrmann, Eric R. Powers, Cindy L. Grines, Steven J. Yakubov, David J. Cohen, H. Graham Parker, Martin J. Frey, Gregg W. Stone, Eric J. Topol, for the TARGET Investigators. Cleveland Clinic Foundation, Cleveland, OH
Journal: Journal of the American College of Cardiology (2001)
OUTCOMES OF PERCUTANEOUS MITRAL VALVE REPAIR IN PATIENTS WTH CHRONIC KIDNEY DISEASE: RESULTS FROM A MULTICENTER REGISTRY
Authors: Neha Maheshwari Mantri, Gagan Singh, Jonathan Yap, Khung Yeo, Jose Condado Contreras, Gaurav Sharma, Benjamin Stripe, Vasilis Babaliaros, Dan Arnett, James McCabe, Mark Reisman, Thomas Smith, Dali Fan, Reginald Low, Jason Rogers
Journal: Journal of the American College of Cardiology (2016)
The global burden of disease of atopic dermatitis from 1990–2017
Journal: British Journal of Dermatology (2021)

Atopic dermatitis (AD; also called atopic eczema) is a common skin disease which can cause a lot of burden.The Global Burden of Disease (GBD) Study provides information on burden of diseases world-wide, including AD.The aim of this study, conducted by a team of researchers and patients from the U.S.A., the U.K. and the Netherlands, was to analyse and report the information on AD from the GBD Study between 1990 and 2017.The GBD Study does not report on individual burden of disease, but on the total burden of disease per country/region, using a measure called DALY-rate (disability adjusted life years).In their 2017 list of the burden of diseases, AD ranked number 15 (1 is highest burden) among all non-fatal diseases.Among skin diseases, AD ranked number 1.Between 1990 and 2017 we found no increase in the burden of AD.But the burden does vary a lot per country and geographical region.We do not know why, but lifestyle factors and wealthiness are probably contributing factors.In 2017, the three countries with the highest disease burden were Sweden, the United Kingdom and Iceland.The lowest three were Uzbekistan, Armenia and Tajikistan.To illustrate the difference: Sweden had a DALY-rate of 326.91 and Tajikistan 85.11.The total number of people world-wide who had AD in 2017 was almost the same as in 1990.We observed a peak in people with AD during early childhood, and this decreased steadily in young adults.But from middle-age onwards, the number of people with AD increased again.The GDP Study confirmed the high burden of disease of AD, but reported no significant change since 1990.It also showed great variety of the burden and the numbers of people with AD per country, geographical region and age-group.The reasons for this variety are not yet fully understood.
Correction
Journal: BMJ (1949)

ANY QUESTIONS?MEDIJRNAL papillae are swollen and are easily damaged, with subsequent bleeding.Occasionally it is found that in comparatively normal patients with healthy gums bleeding is caused by the excessive and over-zealous use of hard toothbrushes.Liver Injection~in Arthritis Q.--a) Is there any evidence to support the giving of liver injections in the anaemia associated with rheumatic and other
Chronic therapy with carvedilol attenuates cardiomyocyte apoptosis in dogs with heart failure Hani N. Sabbah, Ramesh C. Gupta, Suhdish Mishra, Victor G. Sharov, Anastassia Todor, Takayuki Mishima, George Suzuki, Sidney Goldstein. Henry Ford Health System, Detroit, MI
Journal: Journal of the American College of Cardiology (2001)
Epigenetic regulation by gut microbiota
Authors: Vivienne Woo, Theresa Alenghat
Journal: Gut Microbes (2022)

The gastrointestinal tract is continuously exposed to trillions of commensal microbes, collectively termed the microbiota, which are environmental stimuli that can direct health and disease within the host. In addition to well-established bacterial sensing pathways, microbial signals are also integrated through epigenetic modifications that calibrate the transcriptional program of host cells without altering the underlying genetic code. Microbiota-sensitive epigenetic changes include modifications to the DNA or histones, as well as regulation of non-coding RNAs. While microbiota-sensitive epigenetic mechanisms have been described in both local intestinal cells and as well in peripheral tissues, further research is required to fully decipher the complex relationship between the host and microbiota. This Review highlights current understandings of epigenetic regulation by gut microbiota and important implications of these findings in guiding therapeutic approaches to prevent or combat diseases driven by impaired microbiota-host interactions.