Colorectal Cancer Screening in Young Adults
Authors: Amy B. Knudsen, Carolyn M. Rutter, Reinier G.S. Meester, Iris Lansdorp-Vogelaar, Ann G. Zauber, Karen M. Kuntz
Journal: Annals of Internal Medicine (2021)

LettersJuly 2021Colorectal Cancer Screening in Young AdultsAmy B. Knudsen, PhD, Carolyn M. Rutter, PhD, Reinier G.S. Meester, PhD, Iris Lansdorp-Vogelaar, PhD, Ann G. Zauber, PhD, Karen M. Kuntz, ScDAmy B. Knudsen, PhDMassachusetts General Hospital, Boston, MassachusettsSearch for more papers by this author, Carolyn M. Rutter, PhDRAND Corporation, Santa Monica, CaliforniaSearch for more papers by this author, Reinier G.S. Meester, PhDErasmus MC University Medical Center, Rotterdam, the NetherlandsSearch for more papers by this author, Iris Lansdorp-Vogelaar, PhDErasmus MC University Medical Center, Rotterdam, the NetherlandsSearch for more papers by this author, Ann G. Zauber, PhDMemorial Sloan Kettering Cancer Center, New York, New YorkSearch for more papers by this author, Karen M. Kuntz, ScDUniversity of Minnesota, Minneapolis, MinnesotaSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/L21-0245 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR: Montminy and colleagues' (1) recent article highlights the importance of accounting for histologic subtype when estimating the magnitude of the increase in early-onset colorectal cancer (CRC) from the SEER (Surveillance, Epidemiology, and End Results) database. The incidence of both adenocarcinoma and carcinoid/neuroendocrine tumors has been increasing over time among younger adults, but that of carcinoid/neuroendocrine tumors has been increasing at a faster rate.In the accompanying editorial, Bretthauer and associates (2) called on modelers from the Cancer Intervention and Surveillance Modeling Network to update their assessment of the benefits and harms of CRC screening in light of ...References1. Montminy EM, Zhou M, Maniscalco L, et al. Contributions of adenocarcinoma and carcinoid tumors to early-onset colorectal cancer incidence rates in the United States. Ann Intern Med. 2021;174:157-66. [PMID: 33315473]. doi:10.7326/M20-0068 LinkGoogle Scholar2. Bretthauer M, Kalager M, Weinberg DS. Colorectal cancer screening in young adults: about carcinoid tumors and cancer. Ann Intern Med. 2021;174:263-4. [PMID: 33315472]. doi:10.7326/M20-7244 LinkGoogle Scholar3. Knudsen AB, Rutter CM, Peterse EFP, et al. Colorectal Cancer Screening: A Decision Analysis for the U.S. Preventive Services Task Force. AHRQ publication no. 20-0571-EF-2. Agency for Healthcare Research and Quality; 2020. Google Scholar4. Peterse EFP, Meester RGS, Siegel RL, et al. The impact of the rising colorectal cancer incidence in young adults on the optimal age to start screening: microsimulation analysis I to inform the American Cancer Society colorectal cancer screening guideline. Cancer. 2018;124:2964-73. [PMID: 29846933] doi:10.1002/cncr.31543 CrossrefMedlineGoogle Scholar5. Siegel RL, Fedewa SA, Anderson WF, et al. Colorectal cancer incidence patterns in the United States, 1974-2013. J Natl Cancer Inst. 2017;109. [PMID: 28376186] doi:10.1093/jnci/djw322 CrossrefMedlineGoogle Scholar6. Butterly LF, Siegel RL, Fedewa S, et al. Colonoscopy outcomes in average-risk screening equivalent young adults: data from the New Hampshire Colonoscopy Registry. Am J Gastroenterol. 2021;116:171-9. [PMID: 32833734] doi:10.14309/ajg.0000000000000820 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Massachusetts General Hospital, Boston, MassachusettsRAND Corporation, Santa Monica, CaliforniaErasmus MC University Medical Center, Rotterdam, the NetherlandsMemorial Sloan Kettering Cancer Center, New York, New YorkUniversity of Minnesota, Minneapolis, MinnesotaDisclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L21-0245. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoColorectal Cancer Screening in Young Adults: About Carcinoid Tumors and Cancer Michael Bretthauer , Mette Kalager , and David S. Weinberg Metrics Cited byCorrectionCorrection to: Updates on Age to Start and Stop Colorectal Cancer Screening: Recommendations From the US Multisociety Task Force on Colorectal CancerErratumCancer Screening Among Current and Former U.S. Military Personnel Compared to Civilians: A Cross-Sectional Analysis of the Behavioral Risk Factor Surveillance System July 2021Volume 174, Issue 7Page: 1039-1040KeywordsAdenocarcinomaAge groupsCarcinoid tumorColonColorectal cancerForecastingMedical risk factorsRectal cancerSurveillance Epidemiology and End ResultsYoung adults ePublished: 20 July 2021 Issue Published: July 2021 Copyright & PermissionsCopyright © 2021 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...