Direction selectivity in retinal bipolar cell axon terminals
Authors: Akihiro Matsumoto, Weaam Agbariah, Stella Solveig Nolte, Rawan Andrawos, Hadara Levi, Shai Sabbah, Keisuke Yonehara
Journal: Neuron (2021)

(Neuron 109, 2928–2942.e1–e8; September 15, 2021)In the originally published version of this article, there were errors in equations used to determine the length constant (Figures 2D–2F). Although the parameters ri=Ri/πa2 and rm=Rm/2πashould have been used (Hodgkin and Rushton, 1946, Proc. R. Soc. B.), ri=Ri/πa2 and rm=Rm/2πa were used instead. These errors were introduced because an online Brain Science Dictionary that we relied on (https://dx.doi.org/10.14931/bsd.7666) had these errors in their equations. The author of the Brain Science Dictionary has agreed on these errors in response to our inquiry and corrected these on 3 September 2021 (original article with errors: https://bsd.neuroinf.jp/w/index.php?title=%E3%82%B1%E3%83%BC%E3%83%96%E3%83%AB%E7%90%86%E8%AB%96&direction=prev&oldid=46764). These errors caused incorrect values in Figures 2D–2F and suboptimal discussion in the originally published version of the article.The errors do not affect the conclusions of the paper.We apologize for this error. Figures 2D–2F and the related text, as well as the model parameters in STAR Methods, have been modified in the online version of the article.Editorial noteThis correction outlines an error in an underlying formula used to calculate lengths in a passive cable model. This model was added to the paper at the request of reviewers and unfortunately was not checked carefully in re-review. The corrected model is now accurately built but no longer fits entirely with the authors’ initial hypothesis as to how individual branches of bipolar cells can be tuned independently. Thus, the biophysical mechanisms that shape the output of individual bipolar cell axonal branches remain to be fully elucidated. However, the current correction has no bearing on the main conclusion of the paper, which is based on iGluSnFR imaging.Figure 2Passive cable model to simulate electrical spreads of activities along bipolar cell axon terminal branches (original)View Large Image Figure ViewerDownload Hi-res image Download (PPT) (Neuron 109, 2928–2942.e1–e8; September 15, 2021) In the originally published version of this article, there were errors in equations used to determine the length constant (Figures 2D–2F). Although the parameters ri=Ri/πa2 and rm=Rm/2πashould have been used (Hodgkin and Rushton, 1946, Proc. R. Soc. B.), ri=Ri/πa2 and rm=Rm/2πa were used instead. These errors were introduced because an online Brain Science Dictionary that we relied on (https://dx.doi.org/10.14931/bsd.7666) had these errors in their equations. The author of the Brain Science Dictionary has agreed on these errors in response to our inquiry and corrected these on 3 September 2021 (original article with errors: https://bsd.neuroinf.jp/w/index.php?title=%E3%82%B1%E3%83%BC%E3%83%96%E3%83%AB%E7%90%86%E8%AB%96&direction=prev&oldid=46764). These errors caused incorrect values in Figures 2D–2F and suboptimal discussion in the originally published version of the article. The errors do not affect the conclusions of the paper. We apologize for this error. Figures 2D–2F and the related text, as well as the model parameters in STAR Methods, have been modified in the online version of the article. Editorial note This correction outlines an error in an underlying formula used to calculate lengths in a passive cable model. This model was added to the paper at the request of reviewers and unfortunately was not checked carefully in re-review. The corrected model is now accurately built but no longer fits entirely with the authors’ initial hypothesis as to how individual branches of bipolar cells can be tuned independently. Thus, the biophysical mechanisms that shape the output of individual bipolar cell axonal branches remain to be fully elucidated. However, the current correction has no bearing on the main conclusion of the paper, which is based on iGluSnFR imaging. Direction selectivity in retinal bipolar cell axon terminalsMatsumoto et al.NeuronAugust 13, 2021In BriefMatsumoto et al. uncover that cardinal direction selectivity emerges in retinal bipolar cell axon terminals. The selectivity is established de novo at the terminals by starburst amacrine cells, mediated by both cholinergic transmission and wide-field amacrine cells. The bipolar cells transmit tuned glutamate inputs to directional preference-matched ganglion cells. Full-Text PDF Open Access