THU0457 LONGITUDINAL ASSOCIATION OF SEDENTARY TIME AND PHYSICAL ACTIVITY WITH SLEEP QUALITY IN WOMEN WITH FIBROMYALGIA: THE AL-ÁNDALUS PROJECT
Authors: M. Borges Cosic, P. Acosta-Manzano, B. Gavilán Carrera, F. Estévez-López, V. A. Aparicio, V. Segura-Jiménez, M. Delgado-Fernández
Journal: Annals of the Rheumatic Diseases (2020)

Background: Sleep disturbances are common in fibromyalgia, and influences quality of life. Recent literature has suggested that non-pharmacological treatments (e.g., physical exercise and cognitive behavioural therapy) may help to improve sleep quality (SQ) and the management of fibromyalgia 1 . In this regard, sedentary time (ST) and physical activity (PA) intensity levels could play a role on SQ in this population 2 . However, evidence is scarce and mainly based on cross-sectional data. Objectives: This study aimed to examine the longitudinal associations (2- and 5-year follow-up) of ST and PA intensity levels with SQ in women with fibromyalgia. Methods: In this prospective cohort study, women diagnosed with fibromyalgia (age: 51.4±7.6 years) with completed data were included at baseline ( n =409), at 2-year follow-up ( n =214) and at 5-year follow-up ( n =218). Sedentary time and PA intensity levels (light and moderate-to-vigorous [MVPA]) were assessed using triaxial accelerometers worn for consecutive 7 days. The percentage of time spent in different behaviours was calculated (e.g., (ST/accelerometer wear time) × 100). The SQ global score was calculated as a sum of all components (score ranges from 0 to 21 where higher values indicate worse SQ) of the Pittsburgh Sleep Quality Index. Linear regressions were performed to analyse the association of changes in ST and PA over time (predictor variables) with SQ at 2- and 5-years follow-up (dependent variables) while considering baseline SQ, age, fat percentage, marital status, educational level, sleep or relaxation medication, and regular menstruation as confounders. Results: Overall, after adjusting for confounders, non-statistical significant associations were found between changes in ST and PA intensity levels from baseline to 2-years follow-up with SQ at 2-year follow-up ( P&gt; 0.05); except for the change in MVPA from baseline to 2-years follow-up, which showed evidence of statistical significance ( B =-0.207; P= 0.059). Regarding the 5-year follow-up, we did not observe either any association between changes in ST or PA intensity levels from baseline to 5-year follow-up with SQ at 5-year follow-up ( P&gt; 0.05). Conclusion: The main findings suggest that neither ST nor PA intensity levels over time predict SQ at 2- and 5-year follow-up in women with fibromyalgia. Future PA-counselling randomised controlled trials might shed more light on the role that ST and PA could play on SQ. References: [1]Macfarlane GJ, et al. Ann Rheum Dis, 2017; 76(2):318–328. [2]Borges-Cosic M, et al. Scand J Med Sci Sports 2019; 29:266–274. Acknowledgments: This study was supported by the Spanish Ministry of Economy and Competitiveness (I+D+i DEP2010-15639; I+D+I DEP2013-40908-R) and the Spanish Ministry of Education, Culture and Sport (FPU15/00002). Disclosure of Interests: : None declared