tbuckley/cabot-search huggingface dataset:
Emerging Wearable Interfaces and Algorithms for Hand Gesture Recognition: A Survey
Authors: Shuo Jiang, Peiqi Kang, Xinyu Song, Benny Lo, Peter Shull
Journal: IEEE Reviews in Biomedical Engineering (2021)

Hands are vital in a wide range of fundamental daily activities, and neurological diseases that impede hand function can significantly affect quality of life. Wearable hand gesture interfaces hold promise to restore and assist hand function and to enhance human-human and human-computer communication. The purpose of this review is to synthesize current novel sensing interfaces and algorithms for hand gesture recognition, and the scope of applications covers rehabilitation, prosthesis control, exoskeletons for augmentation, sign language recognition, human-computer interaction, and user authentication. Results showed that electrical, mechanical, acoustical/vibratory, and optical sensing were the primary input modalities in gesture recognition interfaces. Two categories of algorithms were identified: 1) classification algorithms for predefined, fixed hand poses and 2) regression algorithms for continuous finger and wrist joint angles. Conventional machine learning algorithms, including linear discriminant analysis, support vector machines, random forests, and non-negative matrix factorization, have been widely used for a variety of gesture recognition applications, and deep learning algorithms have more recently been applied to further facilitate the complex relationship between sensor signals and multi-articulated hand postures. Future research should focus on increasing recognition accuracy with larger hand gesture datasets, improving reliability and robustness for daily use outside of the laboratory, and developing softer, less obtrusive interfaces.
Abstract 12587: Clinical Outcomes of a Nurse-led Post-discharge Education Program for Heart-transplant Recipients
Authors: Ji-hyeon Lee, Seok-min Kang, Young Ah Kim, Sang Hui Chu
Journal: Circulation (2020)

Introduction: Heart transplantation is often more limited than other forms of organ transplants, as hearts can only be donated following brain death. Thus, effective discharge education and follow-up management should be provided to achieve successful clinical outcomes after heart transplantation. This study aimed to examine the effects of a nurse-led program with continuous education on outpatient visits with clinical problems and unplanned first rehospitalization, as compared to an existing discharge education. Methods: Participants’ electronic medical records from 2005 to 2018 were retrospectively analyzed. Participants were 136 recipients received heart transplantation operations and discharge education. Participant data were assigned to three groups: usual care (n = 25), nurse-led program without continuous education (n = 66), and nurse-led program with continuous education (n = 45). The usual care was conventional discharge education, provided to all recipients by ward nurses. In the nurse-led program, the transplant coordinator provided education at discharge and telephone response after discharge. The nurse-led program was divided, according to whether recipients received continuous education and counselling on post-heart transplantation care. Follow-up was provided for recipients regarding outpatient visits with clinical problems and unplanned first rehospitalization for 1 year post-transplantation. Results: The nurse-led program with continuous education was found to be associated with significantly reduced outpatient visits with clinical problems, compared to the usual care ( p = 0.001) and nurse-led program without continuous education ( p &lt; 0.001). Compared to the usual care, the nurse-led program with continuous education was associated with a significant reduction in the risk of unplanned first rehospitalization ( p = 0.011). Conclusions: Discharge education provided by a transplant coordinator using a brochure at discharge, and providing telephone responses for problems or questions and continuing education and counselling after discharge, improved post-transplant clinical outcomes. These finding suggest that nurse-led discharge education programs should be implemented after heart transplantation.
PROGNOSTIC VALUE OF ELEVATED C-REACTIVE PROTEIN AMONG DIABETIC PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION
Authors: Davis B. Jones, Davide Cao, Roxana Mehran, Johny Nicolas, Frans Beerkens, Mauro Chiarito, Matteo Nardin, Samantha Sartori, Hanbo Qiu, Zhongjie Zhang, Gennaro Giustino, Prakash Krishnan, Nitin Barman, Joseph Sweeny, Usman Baber, George Dangas, Samin Sharma, Annapoorna Kini
Journal: Journal of the American College of Cardiology (2021)
Abstract 12135: Documentation of Shared Decision Making Around Primary Prevention Defibrillator Implantations
Authors: Amr F Barakat, Anum Asif, Ana Inashvili, Libby Szeto, Ahmed Noor, Alvin Thalappillil, Shubash Adhikari, Shumail Fatima, Deepak Kumar Pasupula, Shahzad Ahmad, Don Mathew, Aditya Bhonsale, Krishna Kancharla, Norman C Wang, Sandeep Jain, N A Estes, Samir Saba
Journal: Circulation (2019)

Introduction: Patients eligible for primary prevention implantable cardioverter-defibrillator (ICD) are faced with a complex decision that needs a clear understanding of the risks/ benefits of such...
Cognitive Behavioral Therapy for the Eating Disorders
Authors: W. Stewart Agras, Cara Bohon
Journal: Annual Review of Clinical Psychology (2021)

Research findings strongly suggest that cognitive behavioral therapy for the eating disorders (CBT-ED) is more effective than other treatments for bulimia nervosa (BN) and for binge eating disorder (BED), although interpersonal psychotherapy appears to be equally effective for BED. Evidence for the effectiveness of CBT-ED for the persistent (adult) form of anorexia nervosa (AN) is insufficient at present and is essentially absent for AN in adolescents except for some evidence from uncontrolled trials. This article begins with an overview of the early studies in the development of CBT-ED that showed a similar effectiveness of other symptom-focused psychotherapies—a finding that was neglected at the time. Later developments are then considered, including comparisons of CBT-ED with other psychotherapies, efforts to develop Internet-based training and treatment, and electronic applications for treatment. Finally, implications of the findings for future short- and long-term research and for clinical practice are considered.
SUBCLINICAL DETECTION OF CARDIOVASCULAR DISEASE (CVD) IN ASYMPTOMATIC PEOPLE LIVING WITH HIV (PLWH) ON ANTIRETROVIRAL THERAPY (ART) WITHOUT TRADITIONAL CVD RISK FACTORS: PRELIMINARY ANALYSIS OF THE H-ART TO HEART STUDY
Authors: Gavin Manmathan, Nnenna Ngwu, Sana Adam, James Johnson, Callum Little, Tushar Kotecha, Sabine Kinloch de Loes, Margaret A. Johnson, Roby Rakhit
Journal: Journal of the American College of Cardiology (2021)
USE OF SIMULATION FOR ADVANCED RESUSCITATION OF IN-HOSPITAL CARDIAC ARREST PATIENTS WITH SUSPECTED OR CONFIRMED COVID-19
Authors: Laurie-Anne Boivin Proulx, Amélie Doherty, Rousseau-Saine Nicolas, Serge Doucet, Hung Q. Ly, Patrick Lavoie, Nicolas Thibodeau-Jarry
Journal: Journal of the American College of Cardiology (2021)
Socioeconomic deprivation is inversely associated with measles incidence: a longitudinal small-area analysis, Germany, 2001 to 2017
Authors: Sven Rohleder, Christian Stock, Kayvan Bozorgmehr
Journal: Eurosurveillance (2021)

Background Although measles is endemic throughout the World Health Organization European Region, few studies have analysed socioeconomic inequalities and spatiotemporal variations in the disease’s incidence. Aim To study the association between socioeconomic deprivation and measles incidence in Germany, while considering relevant demographic, spatial and temporal factors. Methods We conducted a longitudinal small-area analysis using nationally representative linked data in 401 districts (2001–2017). We used spatiotemporal Bayesian regression models to assess the potential effect of area deprivation on measles incidence, adjusted for demographic and geographical factors, as well as spatial and temporal effects. We estimated risk ratios (RR) for deprivation quintiles (Q1–Q5), and district-specific adjusted relative risks (ARR) to assess the area-level risk profile of measles in Germany. Results The risk of measles incidence in areas with lowest deprivation quintile (Q1) was 1.58 times higher (95% credible interval (CrI): 1.32–2.00) than in those with highest deprivation (Q5). Areas with medium-low (Q2), medium (Q3) and medium-high deprivation (Q4) had higher adjusted risks of measles relative to areas with highest deprivation (Q5) (RR: 1.23, 95%CrI: 0.99–1.51; 1.05, 95%CrI: 0.87–1.26 and 1.23, 95%CrI: 1.05–1.43, respectively). We identified 54 districts at medium-high risk for measles (ARR &gt; 2) in Germany, of which 22 were at high risk (ARR &gt; 3). Conclusion Socioeconomic deprivation in Germany, one of Europe’s most populated countries, is inversely associated with measles incidence. This association persists after demographic and spatiotemporal factors are considered. The social, spatial and temporal patterns of elevated risk require targeted public health action and policy to address the complexity underlying measles epidemiology.
VASCULAR COMPLICATIONS OF PERCUTANEOUS AXILLARY INTRA-AORTIC BALLOON PUMP THERAPY
Authors: Hidefumi Nishida, Tae Song, David Onsager, Ann Nguyen, Jonathan Grinstein, Bow Chung, Bryan Smith, Sara Kalantari, Nitasha Sarswat, Gene Kim, Sean Pinney, Valluvan Jeevanandam, Ross Milner, Takeyoshi Ota
Journal: Journal of the American College of Cardiology (2021)
POST-IRRADIATION PERICARDIAL MESOTHELIOMA PRESENTING AS MIXED CONSTRICTIVE PERICARDITIS AND RESTRICTIVE CARDIOMYOPATHY
Authors: Aditya Mehta, Adam Ladzinski, Anubhav Jain, Akshaya Gadre, Dilpat Kumar, Ankita Aggarwal, Mark Schauer
Journal: Journal of the American College of Cardiology (2021)
TELEHEALTH PROVIDER PERSPECTIVES DURING COVID-19: INSIGHTS FROM AN ACADEMIC CARDIOLOGY PRACTICE
Authors: Megan Lee, Paulina Luna, Shannon Lynch, Sameer Nagpal, Yulanka Castro Dominguez, Zain Ahmed, Aaron Brice, Ahmad Arham, Kim Smolderen, Carlos Mena Hurtado
Journal: Journal of the American College of Cardiology (2021)
Abstract 31: "Cold" Debriefing After Pediatric In-Hospital Cardiac Arrests
Authors: Heather Wolfe, Jesse Wenger, Robert Sutton, Dana Niles, Vinay Nakdarni, Jordan Duval-Arnould, Anita Sen, Adam Cheng
Journal: Circulation (2018)

Background: Cold debriefing(CD) is defined as occurring after at least 1 day to several weeks after a cardiac arrest event. CD has been reported to improve patient survival when implemented in a single institution, however little is known about the nature of cold debriefings across multiple pediatric centers. Methods: Retrospective review of prospectively collected data from the Pediatric Resuscitation Quality Collaborative (pediResQ). The collaborative is comprised of 18 institutions in the US and Canada, reporting 283 cardiac arrest events at the time of analysis. We analyzed CD data from in-hospital cardiac arrest (IHCA) events between Feb 2016 and April 2018. Debriefing content was collected with a Plus/Delta framework and qualitative analysis of debriefing comments was performed utilizing a modified Team Emergency Assessment Measurement (TEAM) Framework. The TEAM framework consists of ten categories: leadership, communication, cooperation, team climate, adaptability, situational awareness (SA), prioritization, clinical standards(CS) (e.g. CPR quality), and other. Univariate and regression models were applied accounting for clustering by site. Results: CD occurred in 33% (93/283) of IHCA events. Median time to debriefing was 25.5 days [IQR 11, 41] with a duration of 60 minutes [20,60]. Median number of facilitators per event was 1 (IQR 1, 1; range 0, 3). Facilitation and/or co-facilitation was performed by physicians 94%(87/93), nurses 18%(17/93) nurse practitioners 9%(8/93) and other 8%(7/93). Attendance was varied across sites (profession, number per debriefing): physicians 12 [IQR 4, 20], nurses 1 [1, 6], RT 0 [0, 1], administrators 1 [0, 1]. Plus comments were most commonly CS 35%(44/127) of comments, cooperation 21%(27/127) and communication 13%(16/127); Delta comments were CS 31%(41/134), cooperation 18%(24/134) communication 10%(13/134) and SA 9%(12/134). There was no difference in age, sex, race, illness category or survival outcome between events that were debriefed vs. not. Conclusions: In a multicenter pediatric IHCA collaborative, cold debriefings were performed after 33% of cardiac arrests. The majority of plus and delta comments could be categorized as clinical standards, followed by cooperation and communication.
PRESENCE AND BURDEN OF CORONARY ATHEROSCLEROSIS IN HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA
Authors: Khurram Nasir, Reed Mszar, Miguel Cainzos-Achirica, Gowtham Grandhi, Alonso Karlezi Rodrigo, Marcio Bittencourt, Eric Bruckert, Luis Diaz-Diaz Jose, Antonio Gallo, Kees Hovingh G., Marcio Miname, Ovidio Muniz-Grijalvo, Jing Pang, Sijbrands de Isla Leopoldo Perez, Tycho Eric Tromp, Gerald Watts, Pedro Mata, Raul Santos
Journal: Journal of the American College of Cardiology (2021)
MYOCARDIAL T1 AND T2 MAPPING BY CARDIOVASCULAR MAGNETIC RESONANCE IN IMMUNE CHECKPOINT INHIBITOR-ASSOCIATED MYOCARDITIS
Authors: Paaladinesh Thavendiranathan, Lili Zhang, Amna Zafar, Syed S. Mahmood, Marcella Cabral, Anju Nohria, Franck Thuny, Dipti Gupta, Sarah E. Hartmann, Jonathan Weinsaft, Hannah K. Gilman, Bojan Kovacina, Caroline Michel, Michael Mahmoudi, Manuel Garcia De Yebenes Castro, Raymond Kwong, Otavio R. Coelho-Filho, Jonathan Afilalo, Eduardo Z. Nicolas, Arun Baksi, Bernd Wintersperger, Eric H. Yang, Alexander R. Lyon, Michael G. Fradley, Tomas Neilan
Journal: Journal of the American College of Cardiology (2021)
Genetic Variants in the HLA-genes Are Associated with PEG-asparaginase Allergy - a Genome Wide Association Study on the NOPHO ALL2008 Protocol
Authors: Sofie Gottschalk Højfeldt, Benjamin Ole Wolthers, Arja Harila-Saari, Päivi Lähteenmäki, Bendik Lund, Jonas Abrahamsson, Morten Tulstrup, Louise Tram Henriksen, Goda Vaitkeviciene, Kaie Pruunsild, Olafur G. Jonsson, Mats Heyman, Kjeld Schmiegelow, Birgitte Klug Albertsen
Journal: Blood (2017)
Delivering clinical research: the UK healthcare system needs a culture that supports research
Authors: David R Katz, Rajat Gupta
Journal: BMJ (2021)

Medical academics welcomed publication of the government’s vision for the future of clinical research delivery.123 For the vision to succeed, however, there needs to be a concerted effort to foster a research friendly environment at every level of medicine.

Throughout their careers, doctors must be able seamlessly to integrate clinical and academic activities. There should be clear and …
Left atrial structure and function of the amyloidogenic <scp>V122I</scp> transthyretin variant in elderly African Americans
Authors: Masatoshi Minamisawa, Riccardo M. Inciardi, Brian Claggett, Sarah A.M. Cuddy, Candida C. Quarta, Amil M. Shah, Sharmila Dorbala, Rodney H. Falk, Kunihiro Matsushita, Dalane W. Kitzman, Lin Y. Chen, Scott D. Solomon
Journal: European Journal of Heart Failure (2021)
ANTICOAGULATION USE VARIES BY REGION IN PATIENTS WITH RECENT DIAGNOSIS OF ATRIAL FIBRILLATION: GLORIA-AF PHASE III DATA
Authors: Bory Kea, Valentina Bayer, Sagar Patel, Peter Larsen, Dana Button, Christine Teutsch, Menno Huisman, Gregory Y.H. Lip, Brian Olshansky
Journal: Journal of the American College of Cardiology (2021)
ARRHYTHMIAS IN NEONATES AND INFANTS AT A TERTIARY CARE CENTER
Authors: Mostafa Abohelwa, Marwan Refaat, Mohamed Atia Ahmed, Maryam Ibrahim, Amr Elgehiny, Patrick Zakka, Isam El Rassi, Fadi Bitar, Ziad Bulbul, Mariam Arabi
Journal: Journal of the American College of Cardiology (2021)
Clinical and social factors associated with involuntary psychiatric hospitalisation in children and adolescents: a systematic review, meta-analysis, and narrative synthesis
Authors: Susan Walker, Phoebe Barnett, Ramya Srinivasan, Esha Abrol, Sonia Johnson
Journal: The Lancet Child & Adolescent Health (2021)

Disparities in involuntary psychiatric hospitalisation between population subgroups have been identified in adults, but little is known about the factors associated with involuntary hospitalisation in children or adolescents. We did a systematic review, meta-analysis, and narrative synthesis to investigate the social and clinical factors associated with involuntary psychiatric hospitalisation among children and adolescents.
Effectiveness of a Guided Web-Based Intervention to Reduce Depressive Symptoms before Outpatient Psychotherapy: A Pragmatic Randomized Controlled Trial
Authors: Lena Violetta Krämer, Sasha-Denise Grünzig, Harald Baumeister, David Daniel Ebert, Jürgen Bengel
Journal: Psychotherapy and Psychosomatics (2021)

Psychotherapy is a first-line treatment for depression. However, capacities are limited, leading to long waiting times for outpatient psychotherapy in health care systems. Web-based interventions (WBI) could help to bridge this treatment gap.This study investigates the effectiveness of a guided cognitive-behavioral WBI in depressive patients seeking face-to-face psychotherapy.A 2-arm randomized controlled trial was conducted. Depressive patients (n = 136) recruited from the waiting lists of outpatient clinics were randomly assigned to an intervention group (IG; treatment as usual [TAU] + immediate access to WBI) or a control group (CG; TAU + access to WBI after follow-up). Depressive symptoms and secondary outcomes were assessed at baseline, 7 weeks, and 5 months after randomization.Mixed-model analyses revealed a significant group × time interaction effect on depressive symptoms (F2, 121.5 = 3.91; p < 0.05). Between-group effect sizes were d = 0.55 at 7 weeks and d = 0.52 at 5 months. The IG was superior regarding psychological symptoms and mental health quality of life but not on physical health quality of life, attitudes, motivation for psychotherapy, or subjective need and uptake of psychotherapy.Patients waiting for face-to-face psychotherapy can benefit from a WBI when compared to TAU. Despite the reduction of depressive symptoms in the IG, the uptake of subsequent psychotherapy was still high in both groups. The effects remained stable at the 5-month follow-up. However, this study could not determine the proportion of specific intervention effects vs. nonspecific effects, such as positive outcome expectations or attention. Future research should focus on the long-term effects and cost-effectiveness of WBI before psychotherapy.
Differences in the Oral Microbiome in Patients With Early Rheumatoid Arthritis and Individuals at Risk of Rheumatoid Arthritis Compared to Healthy Individuals
Authors: Johanna M. Kroese, Bernd W. Brandt, Mark J. Buijs, Wim Crielaard, Frank Lobbezoo, Bruno G. Loos, Laurette van Boheemen, Dirkjan van Schaardenburg, Egija Zaura, Catherine M. C. Volgenant
Journal: Arthritis & Rheumatology (2021)

Objective It has been suggested that rheumatoid arthritis (RA) may originate at the oral mucosa. The aim of the present study was to assess the oral microbiome and periodontal condition in patients with early RA and individuals at risk of developing RA compared to healthy controls. Methods Three groups were recruited (n = 50 participants per group): 1) patients with early RA (meeting the American College of Rheumatology/European Alliance of Associations for Rheumatology 2010 classification criteria), 2) individuals at risk of developing RA (those with arthralgia who were positive for RA‐associated autoantibodies), and 3) healthy controls. A periodontal examination was conducted to assess the presence of bleeding on probing (BOP), pocket probing depth (PPD), and periodontal inflamed surface area (PISA). The microbial composition of subgingival dental plaque, saliva, and tongue coating was assessed using 16S ribosomal DNA amplicon sequencing, and findings were compared between groups with permutational multivariate analysis of variance (PERMANOVA). Results There were no significant differences in any of the 3 periodontal variables between patients with early RA, at‐risk individuals, and healthy controls ( P = 0.70 for BOP, P = 0.30 for PPD, and P = 0.57 for PISA, by Kruskal‐Wallis test). PERMANOVA analyses comparing microbial composition between the groups showed significant differences in the microbial composition of saliva (F = 2.08, P = 0.0002) and tongue coating (F = 2.04, P = 0.008), but not subgingival dental plaque (F = 0.948, P = 0.51). However, in post hoc tests, no significant differences in microbial composition of the saliva or tongue coating were observed between the early RA group and the at‐risk group (F = 1.12, P = 0.28 for saliva; F = 0.834, P = 0.59 for tongue coating). In assessing microbial diversity based on the number of zero‐radius operational taxonomic units per sample, Prevotella in the saliva and Veillonella in the saliva and tongue coating were each found at a higher relative abundance in samples from patients with early RA and at‐risk individuals compared to healthy controls. Conclusion The results show similarities in the oral microbiome between patients with early RA and at‐risk individuals, since in both groups, the oral microbiome was characterized by an increased relative abundance of potentially proinflammatory species when compared to that in healthy controls. These findings suggest a possible association between the oral microbiome and the onset of RA.
A rich meconium metabolome in human infants is associated with early-life gut microbiota composition and reduced allergic sensitization
Authors: Charisse Petersen, Darlene L.Y. Dai, Rozlyn C.T. Boutin, Hind Sbihi, Malcolm R. Sears, Theo J. Moraes, Allan B. Becker, Meghan B. Azad, Piush J. Mandhane, Padmaja Subbarao, Stuart E. Turvey, B. Brett Finlay
Journal: Cell Reports Medicine (2021)
The Risk of Overdose With Concomitant Use of Z-Drugs and Prescription Opioids: A Population-Based Cohort Study
Authors: Alejandro Szmulewicz, Brian T. Bateman, Raisa Levin, Krista F. Huybrechts
Journal: American Journal of Psychiatry (2021)

Objective: The Z-drugs (zolpidem, zopiclone, zaleplon) are widely used to treat insomnia in patients receiving prescription opioids, and the risk of overdose resulting from this coprescription has not been explored. The authors compared the rates of overdose among patients using opioids plus Z-drugs and patients using opioids alone. Methods: All individuals 15 to 85 years of age receiving prescription opioids, regardless of underlying indication and without evidence of cancer, were identified in the IBM MarketScan database (2004–2017). Patients with concomitant exposure to Z-drugs were matched 1:1 to patients with exposure to prescription opioids alone based on opioid prescribed, morphine equivalents, number of days’ supply, and hospitalization within the past 30 days. The primary outcome was any hospitalization or emergency department visit due to an overdose within 30 days, using an intention-to-treat approach. Fine stratification on the propensity score was used to control for confounding. Results: A total of 510,529 exposed patients and an equal number of matched reference patients were analyzed. There were 217 overdose events among the exposed patients (52.5 events per 10,000 person-years) and 57 events among the reference patients (14.4 events per 10,000 person-years), corresponding to an unadjusted hazard ratio of 3.67 (95% CI=2.75, 4.90). Using fine stratification on the propensity score (c-statistic: 0.66), the adjusted hazard ratio was 2.29 (95% CI=1.79, 2.91). Results were consistent across sensitivity analyses. Conclusions: Among patients receiving prescription opioids, after controlling for all confounding factors, concomitant treatment with Z-drugs was associated with a substantial relative increase in the risk of overdose. The potential implications are significant given the large number of opioid-treated patients receiving Z-drugs.