tbuckley/cabot-search huggingface dataset:
Societies.
Journal: JAMA (1903)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Physicians Are Patients Too
Journal: JAMA (1970)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Modulation of lymphatic transport in the central nervous system
Authors: Wenzhong Li, Dawei Chen, Nan Liu, Yongxin Luan, Shoujun Zhu, Haifeng Wang
Journal: Theranostics (2022)

Over the past decade, repeated studies demonstrated that the vertebrate brain had a specialized lymphatic transport pathway, which overturned the traditional concept of central nervous system (CNS) immune privilege. Despite the lack of lymphatic vessels, the glymphatic system and the meningeal lymphatic vessels provide a unique pathway for solutes transport and metabolites clearance in the brain. Sleep, circadian rhythm, arterial pulsation, and other physiological factors modulate this specialized lymphatic drainage pathway. It has also changed significantly under pathological conditions. These modulatory mechanisms may arise critical targets for the therapeutic of CNS disorders. This review highlights the latest research progress on the modulation of lymphatic transport in the CNS under physiological and pathological conditions. Furthermore, we examined the possible upstream and downstream relation networks between these regulatory mechanisms.
Angiofibroma of Soft Tissue on MRI and FDG PET/CT Image
Authors: Liu Xiao, Liu Yang, Yueqi Wang, Lin Li
Journal: Clinical Nuclear Medicine (2022)

Abstract Angiofibroma of soft tissue is a rare benign mesenchymal neoplasm. We reported a case of angiofibroma of soft tissue in a 61-year-old woman. MRI examination indicated a soft tissue mass in the right lower thigh, which showed isosignal intensity on T1-weighted imaging and heterogeneous high signal intensity on T2-weighted imaging. This lesion had intense tracer uptake, with an SUV max of 7.24 on FDG PET/CT. Our case revealed that when soft tissue masses with intense FDG uptake on PET/CT are encountered, angiofibroma of soft tissue should be considered in the differential diagnosis.
American Society of Echocardiography Algorithm for Degenerative Mitral Regurgitation
Authors: Seth Uretsky, Islamiyat Babs Animashaun, Sakul Sakul, Lillian Aldaia, Leo Marcoff, Konstantinos Koulogiannis, Edgar Argulian, Mark Rosenthal, Steven D. Wolff, Linda D. Gillam
Journal: JACC. Cardiovascular imaging (2022)
Medical News
Journal: JAMA (1927)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Post-traumatic stress disorder is a valid and useful diagnosis
Journal: BMJ (2001)

Meningitis in infancy leads to developmental disabilitiesChildren who have meningitis in infancy have a 10-fold increase in the risk of developing permanent severe or moderate disabilities.Bedford et al (p 533) followed up 1717 children aged 5 years who had had meningitis.General practitioners and parents completed questionnaires about the health and development of 1584 children who had had meningitis and 1391 control children.Those in the meningitis group were more likely to have subtle deficits, such as middle ear disease and visual and behavioural problems.There was considerable variation in outcome depending on the age at infection and the causative organism.All children who have had meningitis should be carefully assessed. Post-traumatic stress disorder is a valid and useful diagnosisPost-traumatic stress disorder is a valid and useful diagnosis but it is not the only psychiatric response to trauma.The disorder is associated with high rates of psychiatric comorbidity and impaired social and occupational functioning and has a prevalence of 1%-7.8% in the general population.Mezey and Robbins (p 561) argue that the diagnosis of post-traumatic stress disorder is important for both patients and doctors and that it can be differentiated from other psychiatric diagnoses by biochemical, neuroanatomical, and phenomenological characteristics.Any concerns about the diagnosis in victims of chronic and lifelong trauma could be resolved by further refining the diagnostic criteria.
Ability of the human heart type-fatty acid binding protein to predict early adverse outcomes in patients with suspected acute coronary syndrome in emergency room: A multicenter study Tomoaki Nakata, Tohru Takahashi, Mamoro Hase, Hitoshi Oh-iwa, Akira Hashimoto, Kazuhiko Nagao, Takayuki Matsuki, Hiroshi Kobayashi, Kazufumi Tsuchihashi, Kazuaki Shimamoto. Sapporo Medical University School of Medicine, Sapporo, Japan
Journal: Journal of the American College of Cardiology (2001)
ENTERIC CYSTS
Authors: O. B.  MAYER
Journal: Annals of Internal Medicine (1935)

Case Reports1 December 1935ENTERIC CYSTSO. B. MAYER, M.D., F.A.C.P.O. B. MAYER, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-9-6-797 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptEnteric cysts, sometimes called enterogenous or developmental cysts, are structurally similar to the intestines. Their cavity, containing a mucoid substance, is usually lined by epithelial cells with an underlying layer of lymphoid tissue and smooth muscle. Increasing internal pressure and consequent impairment of blood supply may cause localized atrophy or other structural changes. According to Ewing,1their origin is from some bud or pouch along the intestinal tract, and Evans2believes them to be related to the more common diverticula of childhood. The usual location in the ileocecal area may be explained by the fact that there is a remnant...Bibliography1. EWING J: Neoplastic diseases, 1931, W. B. Saunders, Philadelphia, p. 1030. Google Scholar2. EVANS A: Developmental enterogenous cysts and diverticula, Brit. Jr. Surg., 1929, xvii, 34-83. CrossrefGoogle Scholar3. FRAENKEL E: Über Cysten in Darmkanal, Arch. f. path. Anat., 1882, lxxxvii, 275-285. CrossrefGoogle Scholar4. DRENNEN E: Ileocecal cysts, Arch. Surg., 1931, xxii, 106-120. CrossrefGoogle Scholar5. HAGGARD WD: Enterogenous cyst of ileum causing obstruction in infants, Surg. Clin. N. Am., 1930, x, 713-717. Google Scholar6. BRADLEYHOKE CECC: Ileocecal (enterogenous) cyst, Jr. Pediat., 1933, ii, 614-615. CrossrefGoogle Scholar7. SLESINGER EG: Enteric cyst of large size in boy, Brit. Jr. Surg., 1928, xvi, 333-334. CrossrefGoogle Scholar8. AITKEN RY: Cyst of ileum, Brit. Jr. Surg., 1931, xviii, 521-523. CrossrefGoogle Scholar9. MCLANAHANSTONE SHB: Enterogenous cysts, Surg., Gynec. and Obst., 1934, lviii, 1027-1029. Google Scholar10. JACKSONEWELL JAGH: Enteric cysts, Wisconsin Med. Jr., 1929, xxviii, 118-119. Google Scholar11. SALVIN AA: Retroperitoneal cyst, Med. Jr. and Rec., 1928, cxxvii, 256-259. Google Scholar12. PONCHERMILLES HGG: Cysts and diverticula of intestinal origin, Am. Jr. Dis. Child., 1933, xlv, 1064-1078. Google Scholar13. HUGHES-JONES WE: Enterogenous cysts, Brit. Jr. Surg., 1934, xxii, 134-141. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Columbia, South Carolina*Received for publication February 28, 1935. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byEnterogenous cyst of the stomach report of a caseEnterocystomasEnterogenous cystsSurgical pediatrics 1 December 1935Volume 9, Issue 6Page: 797-805KeywordsAtrophyEpithelial cellsLymphoid tissueSmooth muscles ePublished: 1 December 2008 Issue Published: 1 December 1935 PDF downloadLoading ...
Preliminary results of a phase 1 study of sea-CD40, gemcitabine, nab-paclitaxel, and pembrolizumab in patients with metastatic pancreatic ductal adenocarcinoma (PDAC).
Authors: David Lawrence Bajor, Martin Gutierrez, Gina M. Vaccaro, Ashiq Masood, Ursa Brown-Glaberman, Juneko E. Grilley-Olson, Hedy L. Kindler, Mark Zalupski, Elisabeth I. Heath, Sarina Anne Piha-Paul, Peigen Zhou, Hailing Lu, Sahar Ansari, Jonathan Hayman, Michael W. Schmitt, Andrew L. Coveler
Journal: Journal of Clinical Oncology (2022)

559 Background: SEA-CD40 is an investigational nonfucosylated IgG1 monoclonal agonistic antibody targeted to CD40, expressed on antigen-presenting cells. SEA-CD40 binds with increased affinity to FcγRIIIa resulting in enhanced effector function and CD40 agonism, allowing amplification of immune stimulation and antitumor activity. PDAC can be treated with gemcitabine + nab-paclitaxel (GnP), often with poor survival. Combining chemotherapeutic agents with SEA-CD40 could facilitate robust antigen release and amplified presentation to CD8+ T cells. In preclinical models, the combination of SEA-CD40 and chemotherapy resulted in significant antitumor activity which is further enhanced with anti-PD1 treatment. We present data from an ongoing Phase 1 study (SGNS40-001) in a PDAC cohort evaluating the combination of SEA-CD40, GnP, and pembrolizumab (pembro). Methods: Patients (pts) ≥18 years old with untreated metastatic PDAC and Eastern Cooperative Oncology Group performance scores of 0 or 1 were enrolled. GnP were administered on Days 1, 8, and 15 of each 28-day cycle with 10 or 30 μg/kg SEA-CD40 IV on Day 3. Pembro was administered every 42 days starting on Day 8. Results: As of July 9, 2021, 61 pts were treated: 40 and 21 pts at 10 and 30 μg/kg SEA-CD40, respectively. Minimum follow-up was 5 months. The most frequent treatment-emergent adverse events (TEAEs) are shown in Table. 5 (8%) pts experienced an AE leading to treatment (tx) discontinuation (3 and 2 in 10 and 30 μg/kg SEA-CD40 dose, respectively), 35 (57%) pts experienced a serious TEAE (22 and 13 pts in 10 and 30 μg/kg, respectively). Two tx-related deaths occurred: colitis attributed to pembro, and septic shock attributed to GnP. Pts had transient increases in circulating cytokines and chemokines associated with immune activation and trafficking as well as increases in markers of activation on peripheral NK cells and T cells. Conclusions: The combination of SEA-CD40 + GnP + pembro demonstrated a tolerable safety profile. Evidence of immune activation was observed, consistent with the proposed mechanism of action. Follow-up for response and survival are ongoing. Clinical trial information: NCT02376699. [Table: see text]
Quality of life among colorectal cancer (CRC) survivors participating in a pilot trial of a web-based dietary intervention with text messages.
Authors: Lufan Wang, Stacey Kenfield, Crystal Langlais, Katherine Van Loon, Angela Laffan, Chloe Evelyn Atreya, June M. Chan, Li Zhang, Christine Miaskowski, Yoshimi Fukuoka, Jeffrey A. Meyerhardt, Alan P. Venook, Erin Van Blarigan
Journal: Journal of Clinical Oncology (2022)

42 Background: Diet may be associated with survival and health-related quality of life (HRQOL) among CRC survivors. Behavioral interventions using web and mobile technology are feasible and acceptable approaches to modify dietary behavior. Little is known about the effect of web-based dietary interventions on HRQOL among CRC survivors. Methods: The Survivor Choices for Eating and Drinking study (SUCCEED) was a pilot randomized wait-list controlled trial designed to determine the feasibility and acceptability of a 12-week (wk) web-based dietary intervention with daily text messages. In this secondary analysis, we estimated the effect of the intervention on HRQOL. Between 2017-2018, 50 CRC survivors were randomized (1:1) to intervention or control. Participants in the intervention arm received the intervention in wk 1-12 and were followed from wks 12-24. Participants assigned to the control arm for 1-12 wks had the option to receive the intervention in wks 13-24. In both arms, HRQOL and sleep quality were assessed using the EORTC QLQ–C30 and CR29 and the Pittsburgh Sleep Quality Index at 0, 12, and 24 wks. Within- and between-group mean changes in HRQOL from enrollment to 12 and 24 wks were evaluated using independent t-test and paired t-test. Results: Follow-up was 88% complete at 12 and 24 wks in the intervention arm and 92% and 80% complete at 12 and 24 wks in controls. Participants mean age was 56 ± 9 y; 34% were men, 70% identified as non-Latinx White, 12% identified as Latinx, and 70% had stage III cancer. Between 0 and 12 wks, an increase in emotional functioning was observed in the intervention arm [mean change: 9.1; 95% confidence interval (CI): 2.2,16.0], while a decrease in emotional functioning was observed in controls (mean change: -5.1; 95%CI: -14.5,4.1; between-group mean difference: 14.3; 95%CI: 3.0,25.6). Between 0 and 24 wks, an increase in social functioning (mean change in intervention: 12.1; 95%CI: 2.1,22.1; between-group mean difference: 13.8; 95%CI: 2.1,25.5) and a decrease in fatigue (mean change in intervention: -9.1; 95%CI: -17.1,-1.1; between-group mean difference: -4.1; 95% CI: -15.8,7.6) was observed in the intervention arm. No other measures of HRQOL or sleep quality differed within or between arms. Conclusions: A web-based dietary intervention with daily text messages may improve emotional and social functioning among CRC survivors. Further study to evaluate the effect of web-based interventions on HRQOL among CRC survivors in larger studies may be merited. Clinical trial information: NCT02965521.
In adults aged 75 to 76 y, systematic AF screening reduced morbidity and mortality at 6 y
Authors: Mohammed Yousufuddin, Arshad Jahangir
Journal: Annals of Internal Medicine (2022)

Source Citation Svennberg E, Friberg L, Frykman V, et al. Clinical outcomes in systematic screening for atrial fibrillation (STROKESTOP): a multicentre, parallel group, unmasked, randomised controlled trial. Lancet. 2021;398:1498-1506. 34469764
Revised U.S. Surveillance Case Definition for Severe Acute Respiratory Syndrome (SARS) and Update on SARS Cases—United States and Worldwide, December 2003
Journal: JAMA (2004)

During the 2003 epidemic of severe acute respiratory syndrome (SARS), CDC and the Council of State and Territorial Epidemiologists (CSTE) developed surveillance criteria to identify persons with SARS. The surveillance case definition changed throughout the epidemic as understanding of the clinical, laboratory, and transmission characteristics of SARS-associated coronavirus (SARS-CoV) increased. On June 26, CSTE adopted a position statement to add SARS-CoV disease to the National Notifiable Disease Surveillance System (NNDSS). The position statement included criteria for defining a SARS case for national reporting. On November 3, CSTE issued a new interim position statement with a revised SARS case definition. This report summarizes the new U.S. surveillance case definition for SARS and updates reported cases of SARS worldwide and in the United States.
Perioperative optimization with nutritional supplements in patients undergoing gastrointestinal surgery for cancer: A randomized, placebo controlled feasibility clinical trial.
Authors: Pablo Emilio Serrano Aybar, Sameer Parpia, Marko Simunovic, Emmanuelle Duceppe, Maria Ines Pinto-Sanchez, Mohit Bhandari, Mark Norman Levine
Journal: Journal of Clinical Oncology (2022)

482 Background: Nutritional status is a major determinant of outcomes following surgery. Perioperative nutritional supplementation may improve postoperative outcomes, however, studies on the topic have led to controversial results. Methods: Single-centre, feasibility randomized trial among gastrointestinal cancer patients undergoing surgery, comparing perioperative nutritional supplements versus placebo. The supplements included: protein supplementation (preoperative day 30-6), “immunonutrition” (preoperative day 5-1 and postoperative day 1-5), and carbohydrate loading (surgery day). Primary outcome was enrollment fraction (i.e., enrolled/eligible patients). Secondary outcomes were patient compliance with study packages (target &gt; 70% of total packages provided) and 90-day postoperative complication rate, including postoperative infectious complications. A priori, we considered protocol modifications to improve enrollment fraction and compliance. Results: From October 2018 to March 2020, 495 patients were screened, of which, 144 were eligible and 71 were enrolled (enrollment fraction: 49%, 95%CI, 41-57%). Patients did not enroll for various reasons including refusal without reason (n = 33) and too much burden (n = 25). Protocol modifications did not impact enrollment fraction or compliance. Modifications included decreasing the interval from enrollment to surgery from 4 weeks to 2 weeks, and decreasing the complexity and length of the baseline assessment. Median overall compliance was 80%, lower for intervention versus control arm (67% and 87%, respectively). Postoperative complication rates were similar between control (18/31 (58%, 95% CI: 41-74)) and intervention (22/34 (65%, 95%CI 48-79)) arms. There was a trend for lower postoperative infectious rates in the intervention arm (12/34 (35%, 95%CI 22-52)) compared to control (16/31 (52%, 95%CI 35-68)). Conclusions: A trial like this is feasible, with an enrollment fraction of 49% and an overall patient compliance with study packages of 80%. Pilot trial protocol modifications did not increase these proportions. Clinical trial information: NCT03445260.
Relation between reduced coronary vasodilator capacity and systemic small artery hypertrophy in hypertensive patients with chest pain Carlo Palombo, Damiano Rizzoni, Enzo Porteri, Michaela Koz�kov�, Lorenza M. Muiesan, Giovanni LaCanna, Daniele Guelfi, Carmela Morizzo, Francesca Vittone, Enrico Agabiti-Rosei. Institute of Clinical Physiology, CNR, Pisa, Italy, Department of Internal Medicine, University of Brescia, Brescia, Italy
Journal: Journal of the American College of Cardiology (2001)
PELLAGRA—A PERSISTENT PROBLEM
Journal: JAMA (1933)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Single-cell-resolved dynamics of chromatin architecture delineate cell and regulatory states in zebrafish embryos
Authors: Alison C. McGarvey, Wolfgang Kopp, Dubravka Vučićević, Kenny Mattonet, Rieke Kempfer, Antje Hirsekorn, Ilija Bilić, Marine Gil, Alexandra Trinks, Anne Margarete Merks, Daniela Panáková, Ana Pombo, Altuna Akalin, Jan Philipp Junker, Didier Y.R. Stainier, David Garfield, Uwe Ohler, Scott Allen Lacadie
Journal: Cell Genomics (2022)
Diseases of small coronary arteries
Journal: JAMA (1968)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal