Correction to: <b><i>ZNF582</i> hypermethylation promotes metastasis of nasopharyngeal carcinoma by regulating the transcription of adhesion molecules <i>Nectin‐3</i> and <i>NRXN3</i></b>
Journal: Cancer Communications (2022)

Cancer CommunicationsVolume 42, Issue 3 p. 281-283 ERRATUMOpen Access Correction to: ZNF582 hypermethylation promotes metastasis of nasopharyngeal carcinoma by regulating the transcription of adhesion molecules Nectin-3 and NRXN3 This article corrects the following: ZNF582 hypermethylation promotes metastasis of nasopharyngeal carcinoma by regulating the transcription of adhesion molecules Nectin-3 and NRXN3 Yin Zhao, Xiao-Hong Hong, Kang Li, Ying-Qing Li, Ying-Qin Li, Shi-Wei He, Pan-Pan Zhang, Jun-Yan Li, Qian Li, Ye-Lin Liang, Yang Chen, Jun Ma, Na Liu, Yu-Pei Chen, Volume 40Issue 12Cancer Communications pages: 721-737 First Published online: October 10, 2020 First published: 07 February 2022 https://doi.org/10.1002/cac2.12264AboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Following publication of this article [1], the authors noticed that the mismatched images were inadvertently included in Figure 5 (migration assays of SUNE1-shNRXN3-#2 group in Figure 5I) and Figure 6 (invasion assays of SUNE1-ZNF582+Nectin3 group in Figure 6A). This error has now been corrected online. FIGURE 5Open in figure viewer Both Nectin-3 and NRXN3 are functional targets of ZNF582 in NPC. (A) The mRNA expression level of Nectin-3 in NPC and normal nasopharyngeal tissue samples in the GSE12452 microarray dataset. (B) Correlation between Nectin-3 mRNA expression and ZNF582 expression in the GSE12452 dataset. (C) Western blotting of Nectin-3 in SUEN1 cells transfected with plasmids encoding empty vector, FLAG-Nectin-3, or Nectin-3-shRNAs. (D-E) Cell adhesion, migration, and invasion assays were performed in SUNE1 and HONE1 cells transfected with plasmids encoding control vector or Nectin-3 (D) or transfected with plasmids encoding shControl or Nectin-3-shRNA (E). (F) The mRNA expression level of NRNX3 in the GSE12452 microarray dataset. (G) Correlations between NRNX3 mRNA expression and ZNF582 expression in the GSE12452 dataset. (H) Western blotting of NRXN3 in SUEN1 cells transfected with plasmids encoding shControl or NRXN3-shRNAs. (I) Cell adhesion, migration, and invasion assays were performed in SUNE1 and HONE1 cells transfected with plasmids encoding shControl or NRNX3-shRNA (#1 or #2). Scale bar: 100 μm. All data are presented as mean ± standard deviation of at least three independent experiments. Student's t-test, **P < 0.01; ***P < 0.001. Abbreviations: NPC, nasopharyngeal carcinoma; shControl, control shRNA; shRNA, short-hairpin RNA. FIGURE 6Open in figure viewer ZNF582 inhibits NPC cell adhesion, migration, and invasion via Nectin-3 and NRXN3. (A-B) The cell adhesion, migration, and invasion assays were performed in SUNE1 and HONE1 cells stably overexpressed vector or ZNF582 and co-transfected with plasmids encoding empty vector or Nectin-3. (C-D) The cell adhesion, migration, and invasion assays were performed in SUNE1 and HONE1 cells stably overexpressed vector or ZNF582 and co-transfected with plasmids encoding empty vector or NRNX3-shRNA (#1 and #2). Scale bar: 100 μm. All data are presented as mean ± standard deviation of at least three independent experiments. Student's t-test, *P < 0.05, **P < 0.01, ***P < 0.001. Abbreviations: NPC, nasopharyngeal carcinoma; shControl, control shRNA; shRNA, short-hairpin RNA. The original data has been submitted to the editorial board of Cancer Communications and has been approved. The authors apologize for this oversight. The correction has no effect on the validity and integrity of the work. We thank the first author, Dr. Yin Zhao, for noticing this mistake. Author information Yin Zhao1,†, Xiao-Hong Hong1,†, Kang Li2,†, Ying-Qing Li1,†, Ying-Qin Li1, Shi-Wei He1, Pan-Pan Zhang1, Jun-Yan Li1, Qian Li1, Ye-Lin Liang1, Yang Chen1, Jun Ma1, Na Liu1, Yu-Pei Chen1 Affiliations 1Experimental Research Department, Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center of Cancer Medicine; Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangzhou 510060, Guangdong, P. R. China 2Center for Translational Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, Guangdong, P. R. China †These authors contributed equally to this article Yin Zhao, Xiao-Hong Hong, Kang Li, and Ying-Qing Li contributed equally to this work. Corresponding authors Correspondence to Yu-Pei Chen ( chenyup1@sysucc.org.cn ). REFERENCE 1Zhao Y, Hong XH, Li K, Li YQ, Li YQ, He SW, et al. ZNF582 hypermethylation promotes metastasis of nasopharyngeal carcinoma by regulating the transcription of adhesion molecules Nectin-3 and NRXN3. Cancer Communications (London, England), 2020, 40(12): 721- 737. https://doi.org/10.1002/cac2.12104. Wiley Online LibraryPubMedWeb of Science®Google Scholar Volume42, Issue3March 2022Pages 281-283 FiguresReferencesRelatedInformation