Annals for Hospitalists Inpatient Notes - Clinical Pearls—Methicillin-Resistant <i>Staphylococcus aureus</i> Bacteremia
Authors: Steven Y.C. Tong
Journal: Annals of Internal Medicine (2021)

Web ExclusivesMay 2021Annals for Hospitalists Inpatient Notes - Clinical Pearls—Methicillin-Resistant Staphylococcus aureus BacteremiaSteven Y.C. Tong, MBBS, PhDSteven Y.C. Tong, MBBS, PhDVictorian Infectious Diseases Service, The Royal Melbourne Hospital, and the University of Melbourne, the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia (S.Y.T.).Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/M21-1491 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail A 35-year-old man presented with worsening lumbar back pain over 10 days. He had a history of active injection drug use. On examination, his temperature was 38.9°C, heart rate was 120 beats/min, blood pressure was 115/65 mm Hg, and respiratory rate was 24 breaths/min. No cardiac murmurs were evident. He exhibited tenderness to palpation in the lumbar region. Neurologic examination was normal. Two sets of blood cultures were obtained, and both isolated gram-positive cocci in clusters. Magnetic resonance imaging showed discitis of the L1 to L2 intervertebral disk and an epidural collection anterior to the theca from T12 to L2 ...References1. Rybak MJ, Le J, Lodise TP, et al. Therapeutic monitoring of vancomycin for serious methicillin-resistant Staphylococcus aureus infections: a revised consensus guideline and review by the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases Pharmacists. Am J Health Syst Pharm. 2020;77:835-864. [PMID: 32191793] doi:10.1093/ajhp/zxaa036 CrossrefMedlineGoogle Scholar2. Tong SY, Davis JS, Eichenberger E, et al. Staphylococcus aureus infections: epidemiology, pathophysiology, clinical manifestations, and management. Clin Microbiol Rev. 2015;28:603-661. [PMID: 26016486] doi:10.1128/CMR.00134-14 CrossrefMedlineGoogle Scholar3. Goto M, Schweizer ML, Vaughan-Sarrazin MS, et al. Association of evidence-based care processes with mortality in Staphylococcus aureus bacteremia at Veterans Health Administration hospitals, 2003-2014. JAMA Intern Med. 2017;177:1489-1497. [PMID: 28873140] doi:10.1001/jamainternmed.2017.3958 CrossrefMedlineGoogle Scholar4. Liu C, Bayer A, Cosgrove SE, et al; Infectious Diseases Society of America. Clinical practice guidelines by the Infectious Diseases Society of America for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children. Clin Infect Dis. 2011;52:e18-e55. [PMID: 21208910] doi:10.1093/cid/ciq146 CrossrefMedlineGoogle Scholar5. Iversen K, Ihlemann N, Gill SU, et al. Partial oral versus intravenous antibiotic treatment of endocarditis. N Engl J Med. 2019;380:415-424. [PMID: 30152252] doi:10.1056/NEJMoa1808312 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Victorian Infectious Diseases Service, The Royal Melbourne Hospital, and the University of Melbourne, the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia (S.Y.T.).Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M21-1491.Corresponding Author: Steven Y.C. Tong, MBBS, PhD, Doherty Institute, 792 Elizabeth Street, Melbourne, Australia 3000; e-mail, steven.[email protected]org.au. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoAnnals for Hospitalists - May 2021 David H. Wesorick , Jawad Al-Khafaji , and Matthew Luzum Metrics May 2021Volume 174, Issue 5Page: HO2-HO3 ePublished: 18 May 2021 Issue Published: May 2021 Copyright & PermissionsCopyright © 2021 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...