HUMAN TOXOPLASMOSIS
Authors: P. W. C.
Journal: Annals of Internal Medicine (1953)

Editorial1 November 1953HUMAN TOXOPLASMOSISP. W. C.P. W. C.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-39-5-1134 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptToxoplasma is an obligate intracellular protozoan parasite which is pathogenic for many species of birds and mammals, including man. Although it was first described by Nicolle and Manceaux in 1908 in a North African rodent, the gondi, it was not until 1939 that Wolf, Cowen and Paige brought conclusive proof of its pathogenicity for man in the case of an infant dying of encephalitis. This observation has been abundantly confirmed, and the clinical and pathologic features of the infection in infants have been precisely described (Cowen, Wolf and Paige,1Feldman2). Some of the earlier reports have been considered in a...1 CowenWolfPaige DABH: Toxoplasmic encephalomyelitis. VI. Clinical diagnosis of infantile or congenital toxoplasmosis: survival beyond infancy, Arch. Neurol. and Psychiat. 48: 689, 1943. CrossrefGoogle Scholar2 Feldman HA: The clinical manifestations and laboratory diagnosis of toxoplasmosis, Am. J. Trop. Med. 2: 420-428, 1953. CrossrefMedlineGoogle Scholar3 Editorial: Toxoplasma infection in man, Ann. Int. Med. 20: 832-836, 1944. LinkGoogle Scholar4 SabinFeldman ABHA: Dyes as microchemical indicators of a new immunity phenomenon affecting a protozoan parasite (Toxoplasma), Proc. Soc. Exper. Biol. and Med. 108: 660-663, 1948. Google Scholar5 Sabin AB: Complement fixation test in toxoplasmosis and the persistence of the antibody in human beings, Pediatrics 4: 443-453, 1949. MedlineGoogle Scholar6 PriorCole JACR: Toxoplasmosis. IV. Report of three cases with particular reference to asymptomatic Toxoplasma parasitemia in a young woman, A. M. A. Arch. Int. Med. 92: 314-320, 1953. CrossrefGoogle Scholar7 Frenkel JK: Uveitis and toxoplasmin sensitivity, Am. J. Ophth. 32 (No. 6, Part 2): 127-133, 1949. CrossrefMedlineGoogle Scholar8 Frenkel JK: Pathogenesis, diagnosis and treatment of human toxoplasmosis, J. A. M. A. 140: 369-377, 1949. CrossrefMedlineGoogle Scholar9 Sabin AB: Toxoplasmosis: Current status, and unsolved problems. Introductory remarks, Am. J. Trop. Med. 2: 360-364, 1953. CrossrefMedlineGoogle Scholar10 Sabin AB: Toxoplasmic encephalitis in children, J. A. M. A. 116: 801, 1941. CrossrefGoogle Scholar11 Kass EH: Toxoplasmosis in the human adult, A. M. A. Arch. Int. Med. 89: 759-782, 1952. CrossrefGoogle Scholar12 PinkertonHenderson HRG: A previously unrecognized disease entity simulating the typhus-spotted fever group, J. A. M. A. 116: 807, 1941. CrossrefGoogle Scholar13 Magnusson JH: Symptoms of toxoplasmosis, Nordisk. Med. 45: 344-348, 1951. Abst. J. A. M. A. 146: 1169, 1951. MedlineGoogle Scholar14 Brennan AJ: A syndrome characterized by generalized cutaneous eruption, chorioretinitis and eosinophilia, probably due to chronic toxoplasma infection, Am. J. Med. 7: 431-436, 1949. CrossrefMedlineGoogle Scholar15 Siim JC: Acquired toxoplasmosis, J. A. M. A. 147: 1641-1645, 1951. CrossrefMedlineGoogle Scholar16 Ström J: Toxoplasmosis due to laboratory infection in two adults, Acta med. Scandinav. 139: 244-252, 1951. CrossrefMedlineGoogle Scholar17 KeanGrocott BHRC: Asymptomatic toxoplasmosis, Am. J. Trop. Med. 27: 745-748, 1947. CrossrefMedlineGoogle Scholar18 SyvertonSlavin JTHB: Human toxoplasmosis, J. A. M. A. 131: 957-959, 1946. CrossrefMedlineGoogle Scholar19 Sabin AB: Present status of clinical manifestations of toxoplasmosis in man, J. A. M. A. 150: 1063-1069, 1952. CrossrefMedlineGoogle Scholar20 Wilder HC: Toxoplasma chorioretinitis in adults, A. M. A. Arch. Ophth. 48: 127, 1952. CrossrefMedlineGoogle Scholar21 Eyles DE: The present status of the chemotherapy of toxoplasmosis, Am. J. Trop. Med. 2: 429-444, 1953. CrossrefMedlineGoogle Scholar22 ColePrior CRJA: Toxoplasmosis. III. Study of families exposed to their toxoplasma-infected pet dogs, A. M. A. Arch. Int. Med. 92: 308-313, 1953. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byHyperthermia, Fever and Infectious Diseases 1 November 1953Volume 39, Issue 5Page: 1134-1139KeywordsEncephalitisInfantsIntracellular pathogensPathogensProtozoansToxoplasmaToxoplasmosis ePublished: 1 December 2008 Issue Published: 1 November 1953 PDF downloadLoading ...