tbuckley/cabot-search huggingface dataset:
Overactive WASp in X-linked neutropenia leads to aberrant B-cell division and accelerated plasma cell generation
Authors: Minghui He, Mezida B. Saeed, Julien Record, Marton Keszei, Lia Gonçalves Pinho, Larissa Vasconcelos-Fontes, Roberta D’Aulerio, Rhaissa Vieira, Mariana M.S. Oliveira, Chiara Geyer, Lena Bohaumilitzky, Meike Thiemann, Ekaterina Deordieva, Lieselot Buedts, Joao Pedro Matias Lopes, Dmitry Pershin, Lennart Hammarström, Yu Xia, Xiaodong Zhao, Charlotte Cunningham-Rundles, Adrian J. Thrasher, Siobhan O. Burns, Vinicius Cotta-de-Almeida, Chaohong Liu, Anna Shcherbina, Peter Vandenberghe, Lisa S. Westerberg
Journal: Journal of Allergy and Clinical Immunology (2021)

BackgroundB-cell affinity maturation in germinal center relies on regulated actin dynamics for cell migration and cell-to-cell communication. Activating mutations in the cytoskeletal regulator Wiskott-Aldrich syndrome protein (WASp) cause X-linked neutropenia (XLN) with reduced serum level of IgA.ObjectiveWe investigated the role of B cells in XLN pathogenesis.MethodsWe examined B cells from 6 XLN patients, 2 of whom had novel R268W and S271F mutations in WASp. By using immunized XLN mouse models that carry the corresponding patient mutations, WASp L272P or WASp I296T, we examined the B-cell response.ResultsXLN patients had normal naive B cells and plasmablasts, but reduced IgA+ B cells and memory B cells, and poor B-cell proliferation. On immunization, XLN mice had a 2-fold reduction in germinal center B cells in spleen, but with increased generation of plasmablasts and plasma cells. In vitro, XLN B cells showed reduced immunoglobulin class switching and aberrant cell division as well as increased production of immunoglobulin-switched plasma cells.ConclusionsOveractive WASp predisposes B cells for premature differentiation into plasma cells at the expense of cell proliferation and immunoglobulin class switching. B-cell affinity maturation in germinal center relies on regulated actin dynamics for cell migration and cell-to-cell communication. Activating mutations in the cytoskeletal regulator Wiskott-Aldrich syndrome protein (WASp) cause X-linked neutropenia (XLN) with reduced serum level of IgA. We investigated the role of B cells in XLN pathogenesis. We examined B cells from 6 XLN patients, 2 of whom had novel R268W and S271F mutations in WASp. By using immunized XLN mouse models that carry the corresponding patient mutations, WASp L272P or WASp I296T, we examined the B-cell response. XLN patients had normal naive B cells and plasmablasts, but reduced IgA+ B cells and memory B cells, and poor B-cell proliferation. On immunization, XLN mice had a 2-fold reduction in germinal center B cells in spleen, but with increased generation of plasmablasts and plasma cells. In vitro, XLN B cells showed reduced immunoglobulin class switching and aberrant cell division as well as increased production of immunoglobulin-switched plasma cells. Overactive WASp predisposes B cells for premature differentiation into plasma cells at the expense of cell proliferation and immunoglobulin class switching.
85P Correlation between nCOUNTER PAM-50 assay and three IHC-based surrogate intrinsic breast cancer subtype classifiers: A real-world study
Authors: M. Martín, M. Del Monte-Millán, Y. Jerez, I. Echavarria Diaz-Guardamino, B. Herrero Lopez, S. Gamez Casado, M. Roche-Molina, I. Marquez-Rodas, M. Cebollero, E. Alvarez, T. Massarrah, I. Ocaña, A. Arias, J.Á. García Saenz, F. Moreno Anton, C. Olier Garate, D. Moreno Muñoz, D. Marrupe Gonzalez, T. Merina, S. Lopez-Tarruella Cobo
Journal: Annals of Oncology (2022)
A national precision cancer medicine implementation initiative for Norway
Authors: Kjetil Taskén, Hege E. G. Russnes, Eline Aas, Line Bjørge, Egil S. Blix, Terje C. Ahlquist, Nyosha Alikhani, Ali Areffard, Eli Bergli, Hege Edvardsen, Gry Festervoll, Grethe S. Foss, Petter Foss, Ingvild Hagen, Kåre B. Hagen, Håvard H. Hauge, Bjorn V. Herikstad, Kristian Hveem, Elisabeth Jarnaess, Kristin Kittelsen, Kristin Krogsrud, Monica Larsen, Mariam Lofwander, Birgitte Lygren, Aslaug Muggerud, Cathrine S. Notland, Ole A. Oppdalshei, Ravinder Singh, Svein Skeie, Fredrik Sund, Lars P. Strand, Lidziya Ulvenes, Giske Ursin, Sverrir Valgardsson, Pål Wiik, Naoko Yamagata, Espen Enerly, Gro L. Fagereng, Åsmund Flobak, Bjørnar Gilje, Bjørn T. Gjertsen, Tormod K. Guren, Jutta Heix, Eivind Hovig, Randi Hovland, Thomas Berg, Diana L. Bordin, Hans-Rickard Brattbakk, Richard Doughty, Kari Ersland, Rakel Forthun, Einar Gudlaugsson, Hanne Hamre, Hans Kristian Haugland, Emiel Janssen, Mari Jebens, Tonje Lien, Susanne Lorenz, Torben Lüders, Pitt Niehusmann, John C. Noone, Vigdis Nygaard, Ulla Randen, Anne Renolen, Anne J. Skjulsvik, Sigmund V. Sperstad, Olav K. Vintermyr, Daniel Vodak, Teresia Wangensteen, Ragnhild M. Wold, Kristin Åberg, Gro Live Fagereng, Khalid Al-Shibli, Yvonne Andersson, Egil Blix, Bodil Bjerkehagen, Sigmund Brabrand, Odd Terje Brustugun, Marte G. Cameron, Astrid Dalhaug, Dalia Dietzel, Tom Dønnem, Ragnhild S. Falk, Sverre Fluge, Bjørn H. Grønberg, Kari Grønås, Hanne Hamre, Åse Haug, Daniel Heinrich, Geir Olav Hjortland, Gunnar Houge, Ann-Charlotte Iversen, Stian Knappskog, Jon Amund Kyte, Hedda von der Lippe Gythfeldt, Kristina Lindemann, Ragnhild A. Lothe, Jo-Åsmund Lund, Per Eystein Lønning, Leonardo Meza-Zepeda, Monica C. Munthe-Kaas, Olav T. D. Nguyen, Pitt Niehusmann, Katarina Puco, Anne H. Ree, Tonje B. Riste, Karin Semb, Eli Sihn S. Steinskog, Andreas Stensvold, Pål Suhrke, Øyvind Tennøe, Geir E. Tjønnfjord, Liv J. Vassbotn, Sissel F. Wahl, Per E. Lønning, Leonardo A. Meza-Zepeda, Per M. Mæhle, Hilde L. Nilsen, Steinar Ø. Thoresen, Ketil Widerberg, Sigbjørn Smeland, Åslaug Helland
Journal: Nature Medicine (2022)
202P Abemaciclib in HR+/Her2- metastatic breast cancer patients after previous progression on palbociclib or ribociclib: Clinical experience in a tertiary hospital in Madrid, Spain
Authors: A. De Luna Aguilar, F. Moreno Anton, J.D. Benitez Fuentes, J. Ortega Anselmi, J. Olalla Inoa, P. Flores Navarro, J.Á. García Saenz
Journal: Annals of Oncology (2022)
A SERVICE EVALUATION OF UNITED KINGDOM ENDOSCOPY USING THE NATIONAL ENDOSCOPY DATABASE
Authors: D. Beaton, M. Rutter, L. Sharp, N. Trudgill, M. Thoufeeq, J. Docherty, B. Nicholson, P. Rogers
Journal: Endoscopy (2022)

Aims The aim of this study was to undertake an evaluation of current UK endoscopy practice, to inform service planning.
FDA Approval Summary: Idecabtagene Vicleucel for Relapsed or Refractory Multiple Myeloma
Authors: Poornima Sharma, Bindu Kanapuru, Bindu George, Xue Lin, Zhenzhen Xu, Wilson W. Bryan, Richard Pazdur, Marc R. Theoret
Journal: Clinical Cancer Research (2022)

In March 2021, the FDA approved idecabtagene vicleucel, a chimeric antigen receptor T-cell therapy targeting the B-cell maturation antigen (BCMA), for adult patients with relapsed/refractory multiple myeloma (RRMM) after ≥4 lines of therapy including an immunomodulatory agent, a proteasome inhibitor, and an anti-CD38 mAb. Approval was based on overall response rate (ORR), complete response (CR) rate, and duration of response (DOR) in 100 adult patients with RRMM treated with idecabtagene vicleucel in a single-arm trial. Patients received a single infusion of idecabtagene vicleucel, preceded by lymphodepleting chemotherapy with cyclophosphamide and fludarabine. Of the 100 patients in the efficacy evaluable population, ORR was 72% [95% confidence interval (CI), 62-81] with stringent CR rate of 28% (95% CI, 19-38). After median follow-up of 10.7 months, median DOR was 11 months (95% CI, 10.3-11.4) in responders (partial response or better) and 19 months [95% CI, 11.4 months, not estimable (NE)] in patients who achieved stringent CR. Serious adverse reactions occurred in 67% of 127 patients evaluated for safety. Grade 3 or higher cytokine release syndrome and neurologic toxicities occurred in 9% and 4%, respectively, leading to a Risk Evaluation and Mitigation Strategy. Hemophagocytic lymphohistiocytosis/macrophage activation syndrome occurred in 4%, with two fatalities. Prolonged cytopenia requiring hematopoietic rescue occurred in 2% (3/127), with two fatalities.
Quality and Safety in Health Care, Part LXXX
Authors: Jay A. Harolds, Laura B. Miller
Journal: Clinical Nuclear Medicine (2020)

Abstract The National Database for Nursing Quality Indicators is an important source of information used to benchmark nursing by unit category in multiple areas related to not only structure and process but also outcome. It also provides some information regarding best practices and the cost to achieve certain results. The Practice Environment Scale of the Nursing Work Index is a frequently used way to measure the professional practice environment of nurses and the relationship of the latter to quality, safety, and other outcomes.
ENDOSCOPIC FOLLOW-UP OF RADICALLY RESECTED SUBMUCOSAL ADENOCARCINOMA IN BARRETT’S ESOPHAGUS: EARLY RESULTS OF AN ONGOING PROSPECTIVE, INTERNATIONAL, MULTICENTER COHORT REGISTRY (PREFER TRIAL)
Authors: M.W. Chan, E.A. Nieuwenhuis, M. Jansen, K. Belghazi, W.B. Nagengast, J. Westerhof, A.D. Koch, M.D.W. Spaander, R. Bisschops, G. De Hertogh, M.J. Bourke, H. Neuhaus, B.L.A.M. Weusten, A. Alkhalaf, O. Pech, C. Schlag, S. Seewald, M.H.M.G. Houben, E.J. Schoon, E. Coron, R. Haidry, H. Messmann, S.L. Meijer, J.J.G.H.M. Bergman, R.E. Pouw
Journal: Endoscopy (2022)

Aims Endoscopic follow-up (FU) may be a valid alternative for patients with submucosal esophageal adenocarcinoma (T1b EAC) We aim to evaluate the safety of a watchful waiting strategy in patients treated endoscopically for T1b EAC.
COMPLICATIONS OF ENDOSCOPIC RETROGRADE CHOLANGIO-PANCREATOGRAPHY(ERCP): A PROSPECTIVE COHORT STUDY
Authors: K. Das, A. Sharma, S. Chowdhury
Journal: Endoscopy (2022)

Methods Prospective observational cohort study. Consecutive patients with native papilla referred for ERCP in two tertiary-care centers, one academic-public and other private, between August, 2018 to July, 2019, in Kolkata, India were enrolled, if they satisfied the inclusion and exclusion criteria, after informed consent. ERCP was done in prone position under conscious sedation with Propofol according to standard indications. The pre-ERCP and peri-procedural details were recorded in a structured Proforma. The definition of AEs and Incidents were according to ASGE Quality Task Force Recommendations 2010. Post-ERCP all patients were followed for 30-days, either physically or on telephone or by contacting the treating physician. Institutional Ethical Clearance was obtained. Standard statistical analysis was performed. A two-tailed p-value<0.05 was considered significant.
Transesophageal endoscopic ultrasound-guided coil and cyanoacrylate treatment of challenging esophageal varices bleeding associated with CREST syndrome ulcerative esophagitis
Authors: Jérôme Rivory, Mathieu Pioche, Jérôme Dumortier, Thomas Lambin, Alexandru Lupu, Charles-Eric Ber, Pierre-Jean Valette
Journal: Endoscopy (2022)

Ligation is the recommended endoscopic treatment for acute esophageal variceal bleeding [1]. It can be challenging when associated with esophagitis. There is abundant evidence regarding the safety and efficacy of coil and glue embolization [2] [3] even in primary prophylaxis for gastric varices [4].
A VISUALIZATION SYSTEM OF ESOPHAGEAL CANCER FEATURES BASED ON DEEP LEARNING
Authors: R. Luo, L. Zhang, S. Hu, H. Yu
Journal: Endoscopy (2022)

Aims Esophageal cancer is the sixth leading cause of cancer deaths worldwide. Superficial esophageal squamous cell carcinoma (SESCC) is recommended to be treated with endoscopic treatment when invasion depths are diagnosed as EP-SM1. When the depth of invasion is deeper than SM2, surgery or chemotherapy are recommended. Therefore, identifying the depth of invasion of SESCC is crucial to determine the treatment measure. In this study, we propose a new method for diagnosing the invasion depth of SESCC.
AN ARTIFICIAL INTELLIGENCE-BASED SYSTEM FOR AUTOMATICALLY MEASURING THE SIZE OF ENDOSCOPIC GASTROINTESTINAL LESIONS
Authors: J. Wang, B. Chen, H. Yu
Journal: Endoscopy (2022)

Aims In the process of gastrointestinal endoscopy, it is necessary to measure the size of lesion, which is one of the bases for the risk classification and treatment of various diseases. We aimed at developing an artificial intelligence-based system for measuring the size of gastrointestinal lesions in real-time. We intended to assess the accuracy of the system on a 3D colon model and endoscopic patients.
RADIATION EXPOSURE DURING MODERN THERAPEUTIC EUS PROCEDURES: IMPLICATIONS FOR PATIENTS AND HEALTH-CARE WORKERS
Authors: G. Vanella, G. Dell'Anna, A. Loria, M.C. Petrone, A. Del Vecchio, P.G. Arcidiacono
Journal: Endoscopy (2022)

Aims Therapeutic EUS (t-EUS) is increasingly adopted in daily clinical practice of tertiary referral centres; however, little is known about procedure-related Radiation Exposure (RE) metrics.
ENDOSCOPIC ULTRASOUND FINE-NEEDLE ASPIRATION OF PANCREATIC CYSTIC LESIONS, A SINGLE-CENTER EXPERIENCE, AND COMPARISON WITH RESECTION HISTOLOGY
Authors: T. Koller, A. Piotrowicz, M. Tomáš, V. Gál
Journal: Endoscopy (2022)

Aims Pancreatic cystic lesions (PCLs) are frequent and some have malignant potential. The decision on performing EUS-FNA and/or surgery remains challenging. We aimed to evaluate the feasibility and diagnostic yield of EUS FNA, and compare results of EUS-FNA with the resection histology.
E-Cigarette Use and Risk of Cardiovascular Disease: A Longitudinal Analysis of the PATH Study (2013–2019)
Authors: Jonathan B. Berlowitz, Wubin Xie, Alyssa F. Harlow, Naomi M. Hamburg, Michael J. Blaha, Aruni Bhatnagar, Emelia J. Benjamin, Andrew C. Stokes
Journal: Circulation (2022)
163O Patient-reported outcomes (PROs) from DESTINY-Breast03, a randomized phase III study of trastuzumab deruxtecan (T-DXd) vs trastuzumab emtansine (T-DM1) in patients (pts) with HER2-positive (HER2+) metastatic breast cancer (MBC)
Authors: G. Curigliano, K. Dunton, M. Rosenlund, M. Janek, J. Cathcart, Y. Liu, P.A. Fasching, H. Iwata
Journal: Annals of Oncology (2022)
Precision spinal gene delivery-induced functional switch in nociceptive neurons reverses neuropathic pain
Authors: Takahiro Tadokoro, Mariana Bravo-Hernandez, Kirill Agashkov, Yoshiomi Kobayashi, Oleksandr Platoshyn, Michael Navarro, Silvia Marsala, Atsushi Miyanohara, Tetsuya Yoshizumi, Michiko Shigyo, Volodymyr Krotov, Stefan Juhas, Jana Juhasova, Duong Nguyen, Helena Kupcova Skalnikova, Jan Motlik, Hana Studenovska, Vladimir Proks, Rajiv Reddy, Shawn P. Driscoll, Thomas D. Glenn, Taratorn Kemthong, Suchinda Malaivijitnond, Zoltan Tomori, Ivo Vanicky, Manabu Kakinohana, Samuel L. Pfaff, Joseph Ciacci, Pavel Belan, Martin Marsala
Journal: Molecular Therapy (2022)

Second-order spinal cord excitatory neurons play a key role in spinal processing and transmission of pain signals to the brain. Exogenously induced change in developmentally imprinted excitatory neurotransmitter phenotypes of these neurons to inhibitory has not yet been achieved. Here, we use a subpial dorsal horn-targeted delivery of AAV (adeno-associated virus) vector(s) encoding GABA (gamma-aminobutyric acid) synthesizing-releasing inhibitory machinery in mice with neuropathic pain. Treated animals showed a progressive and complete reversal of neuropathic pain (tactile and brush-evoked pain behavior) that persisted for a minimum of 2.5 months post-treatment. The mechanism of this treatment effect results from the switch of excitatory to preferential inhibitory neurotransmitter phenotype in dorsal horn nociceptive neurons and a resulting increase in inhibitory activity in regional spinal circuitry after peripheral nociceptive stimulation. No detectable side effects (e.g., sedation, motor weakness, loss of normal sensation) were seen between 2 and 13 months post-treatment in naive adult mice, pigs, and non-human primates. The use of this treatment approach may represent a potent and safe treatment modality in patients suffering from spinal cord or peripheral nerve injury-induced neuropathic pain.
172P Long-term follow-up of randomized controlled trial (RCT) of locoregional treatment versus not of the primary tumour in de-novo metastatic breast cancer
Authors: N.S. Nair, R. Hawaldar, V. Parmar, S. Siddique, I. Mittra, V. Vanmali, S. Joshi, S. Gupta, R. Badwe
Journal: Annals of Oncology (2022)
EFFECTIVENESS OF DIFFERENT VOLUMES OF PEG PREPARATION FOR COLONOSCOPY IN THE ELDERLY: A RETROSPECTIVE ANALYSIS OF A PROSPECTIVE COHORT
Authors: M. Marcello, E. Sinagra, S. Sferrazza, G. Scalisi, G. Morreale, A. Vitello, D. Schillaci, M. Manganaro, S. Camilleri
Journal: Endoscopy (2022)

Aims To assess the effectiveness of different volumes of polyethylene glycol (PEG) preparations for colonoscopy and other factors associated with cleansing success in the elderly.
CHARACTERIZATION COMPARISON BETWEEN TWO CAD SYSTEMS (COMBO CAD STUDY) IN REAL-LIFE ENDOSCOPY: AN INTERIM ANALYSIS
Authors: C. Hassan, M. Spadaccini, L. Alfarone, L. Da Rio, V. Solitano, S. Ferretti, V. Poletti, R. Maselli, S. Carrara, P.A. Galtieri, G. Pellegatta, A. Fugazza, A. Anderloni, L.M. Terracciano, P. Spaggiari, A. Repici
Journal: Endoscopy (2022)

Aims Implementation of clinical strategies based on optical diagnosis of < 5 mm rectosigmoid polyps may lead to a substantial saving of economic and financial resources. Artificial intelligence(AI)has the potential to help in making the characterization process more reliable and objective. We compared the performances in rectosigmoid polyp characterization of two recently approved CADx systems(CAD-EYE,CAD A,and GI-Genius,CAD B)working in blue- and white-light.
GIANT ZENKER DIVERTICULA: IS ENDOSCOPIC TREATMENT AN OPTION?
Authors: C. Ginestet, M. Barret, A. Belle, E. Abou Ali, R. Hallit, A. Assaf, R. Coriat, S. Chaussade
Journal: Endoscopy (2022)

Aims Zenker's diverticulum usually presents in the elderly population with symptoms of dysphagia. The endoscopic diverticulotomy can be performed using either cap or diverticuloscope assistance. The abandonment of the diverticuloscope for the treatment of diverticula allows to perform a complete septotomy of the diverticular wall in particular in the case of large diverticula (greater than 5 cm). The aim of this study was to evaluate the safety and feasibility of complete septotomy in the setting of large Zenker's diverticula.
Arterial wall rejuvenation: the potential of targeting matrix metalloprotease 2 to treat vascular aging
Authors: Amrut V Ambardekar, Mary C M Weiser-Evans, Timothy A McKinsey
Journal: Cardiovascular Research (2022)

The aorta and carotid arteries are large, elastic vessels that serve as conduits for transporting blood to smaller, more muscular-resistance arteries. The elastic properties of these large vessels enable absorption of the pulsatile load emerging from the left ventricle (LV) of the heart, reducing forward oscillating energy transmission and thereby protecting downstream-resistance arteries from damage.1 Stiffening of the aorta and carotid arteries is commonly observed with aging, and is an independent risk factor for the development of cardiovascular diseases such as coronary artery disease, heart failure, and stroke.1,2 There is also a cycle whereby co-existing risk factors, including hypertension, tobacco use, metabolic syndrome, and diabetes, contribute to further vascular stiffening. Given the estimate that by 2050, >15% of the world's population will be over age 65, and the ever-increasing prevalence of relevant co-morbidities, there is a pressing need to develop innovative therapeutic strategies to tackle vascular aging. The pathophysiology of age-dependent arterial stiffening is multifactorial and includes changes in dynamic components of vessel vasoreactivity as well as static components of the arterial wall itself. Endothelial cell (EC) dysfunction due to inhibition of endothelial nitric oxide synthase (eNOS) and the consequent reduction of nitric oxide (NO) bioavailability impairs vascular smooth muscle cell (VSMC) vasoreactivity in the aorta and carotid arteries. In addition, within the medial layer of the vessels, concomitant degradation of elastin and accumulation of collagen result in elevated vascular stiffness due to the significantly higher tensile strength of collagen compared with elastin. The increased pulsatile pressure resulting from the elevated vascular tone and stiffening of the large arteries extends to the microcirculation of vasodilated organs such as the brain and kidneys, and can predispose to cerebral lacunar infarcts and kidney dysfunction and albuminuria. Furthermore, elevated blood pressure resulting from vascular aging can cause LV hypertrophy and ventricular stiffening leading to diastolic dysfunction, and the low diastolic pressures under these conditions reduce coronary blood flow and can aggravate myocardial ischaemia.
Oligodendrocyte death and myelin loss in the cuprizone model: an updated overview of the intrinsic and extrinsic causes of cuprizone demyelination
Authors: Martin Zirngibl, Peggy Assinck, Anastasia Sizov, Andrew V. Caprariello, Jason R. Plemel
Journal: Molecular Neurodegeneration (2022)

Abstract Background The dietary consumption of cuprizone – a copper chelator – has long been known to induce demyelination of specific brain structures and is widely used as model of multiple sclerosis. Despite the extensive use of cuprizone, the mechanism by which it induces demyelination are still unknown. With this review we provide an updated understanding of this model, by showcasing two distinct yet overlapping modes of action for cuprizone-induced demyelination; 1) damage originating from within the oligodendrocyte, caused by mitochondrial dysfunction or reduced myelin protein synthesis. We term this mode of action ‘intrinsic cell damage’. And 2) damage to the oligodendrocyte exerted by inflammatory molecules, brain resident cells, such as oligodendrocytes, astrocytes, and microglia or peripheral immune cells – neutrophils or T-cells. We term this mode of action ‘extrinsic cellular damage’. Lastly, we summarize recent developments in research on different forms of cell death induced by cuprizone, which could add valuable insights into the mechanisms of cuprizone toxicity. With this review we hope to provide a modern understanding of cuprizone-induced demyelination to understand the causes behind the demyelination in MS.
PLACE OF A SYSTEMATIC UPPER GASTROINTESTINAL ENDOSCOPY IN CROHN'S DISEASE
Authors: A. Hassine, I. Akkari, S. Mrabet, E. Ben Jazia
Journal: Endoscopy (2022)

Aims Esophagogastroduodenoscopy (EGD) with the realization of biopsies, in Crohn's disease (CD), researchs upper locations of the disease. Our study aimed to study the interest of systematic EGD with anatomopathological study in the detection of upper CD locations.
98P Neo-CheckRay, radiation therapy and adenosine pathway blockade to potentiate benefit of immuno-chemotherapy in early stage luminal B breast cancer: Results of the safety run-in phase
Authors: A. De Caluwe, E. Romano, P. Poortmans, A. Gombos, A. Laragione, E. Agostinetto, G. Nader Marta, S. Picchia, C. Vandekerkhove, L. Ameye, L. Craciun, I. Veys, D. Van Gestel, D. Larsimont, C. Sotiriou, M. Piccart, M. Ignatiadis, L. Buisseret
Journal: Annals of Oncology (2022)
144P The differences in fatty acid profiles and stearoyl-CoA desaturase (SCD1) mRNA level in adipose tissue surrounding breast tumor of Iranian women with breast cancer and benign breast disease
Authors: R. Sefidabi, A. Moini, A. Alizadeh, S. Alipour, R. Omranipoor, M. Hafezi, M. Shahhoseini, A. Izadi, S. Vesali
Journal: Annals of Oncology (2022)
COMPARISON OF ENDOSCOPIC BAND LIGATION AND ARGON PLASMA COAGULATION FOR MANAGEMENT OF GASTRIC VASCULAR ECTASIAS IN PATIENTS OF CHRONIC LIVER DISEASE
Authors: A. Salim, M. Akram, T. Ahmed, O. Farooq, K. Malik
Journal: Endoscopy (2022)

Aims To compare the efficacy of endoscopic band ligation (EBL) and argon plasma coagulation (APC) for management of gastric vascular ectasias (GVE).