THROMBOSIS OF THE HEPATIC VEINS—CHIARI'S SYNDROME; REPORT OF A CASE WITH BIOPSY AND VENOUS PRESSURE DETERMINATION
Authors: Sidney Kahn, Maxwell Spring
Journal: Annals of Internal Medicine (1940)

Case Reports1 December 1940THROMBOSIS OF THE HEPATIC VEINS—CHIARI'S SYNDROME; REPORT OF A CASE WITH BIOPSY AND VENOUS PRESSURE DETERMINATIONSIDNEY KAHN, M.D., MAXWELL SPRING, M.D.SIDNEY KAHN, M.D.Search for more papers by this author, MAXWELL SPRING, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-14-6-1075 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptObstruction to the blood flow through the hepatic veins leads to a pathological-clinical entity known as Chiari's syndrome, of which there have been reported, as far as we could determine, approximately 60 cases, and which combines the clinical picture of portal obstruction and hepatic degeneration. The disease is undoubtedly often overlooked because of its similarity to the late stages of atrophic cirrhosis (Laennec's).We are reporting a case because of its rarity, and because the clinical study included venous pressure determinations which aided in the diagnosis.INTRODUCTIONIn 1846, Budd commented on cases of intrahepatic abscesses that involved one of...References1. BUDD G: Diseases of the liver, 1846, Lea and Blanchard, Philadelphia, p. 151. Google Scholar2. SCHÜPPEL O, quoted by SOHVAL, A. R.: Hepatic complications in polycythemia vera, with particular reference to thrombosis of the hepatic and portal veins and hepatic cirrhosis, Arch. Int. Med., 1938, lxii, 925-945. Google Scholar3. CHIARI H: Ueber die selbständige Phlebitis obliterans der Hauptstämme der Venae hepaticae als Todesursache, Beitr. z. path. Anat. u. z. allg. Path., 1899, xxvi, 1-17. Google Scholar4. HESS AF: Fatal obliterating endophlebitis of the hepatic veins, Am. Jr. Med. Sci., 1905, ciii, 986-1000. 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SOHVAL AR: Hepatic complications in polycythemia vera (see 2). Google Scholar13. ALTSHULEWHITE MDG: Chiari's syndrome in a patient with polycythemia vera, New Eng. Jr. Med., 1939, ccxx, 1032-1033. Google Scholar14. SIMONDSCALLAWAY JPJW: Anatomical changes in the livers of dogs following mechanical constriction of the hepatic veins, Am. Jr. Path., 1932, viii, 159-163. Google Scholar15. SIMONDSJERGESEN JPFH: Late changes in the liver induced by mechanical obstruction of the hepatic veins, Arch. Path., 1935, xx, 571-581. Google Scholar16. SAVIN LH: Clinical and postmortem notes on a case of "Budd's" (or "Chiari's") disease in which thrombosis of the hepatic veins and of the inferior vena cava was preceded, perhaps fortuitously, by exudative retinitis, iridocyclitis and secondary glaucoma, Trans. Ophth. Soc. U. Kingdom, 1934, liv, 326-336. Google Scholar17. RIGDON RH: Relation between thrombophlebitis of the inferior vena cava and occlusion of the hepatic veins, Bull. Johns Hopkins Hosp., 1933, liii, 162-171. Google Scholar18. WILENSKY AO: Hepato-renal syndrome, a review, Arch. Surg., 1939, xxxviii, 625. CrossrefGoogle Scholar19. JACOBSONGOODPASTURE VCEW: Occlusion of the entire inferior vena cava by hypernephroma with thrombosis of the hepatic vein and its branches, Arch. Int. Med., 1918, xxii, 86-95. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Bronx, New York*Received for publication October 21, 1939.From the Surgical Service of Dr. William Klein, The Bronx Hospital, New York. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByProposal of a new nomenclature for budd-chiari syndrome: Hepatic vein thrombosis versus thrombosis of the inferior vena cava at its hepatic portionThe Budd-Chiari syndrome in pregnancy.The Budd-Chiari syndrome after pregnancyTHE BUDD-CHIARI SYNDROME IN PREGNANCYBUDD-CHIARI SYNDROME (OCCLUSION OF THE HEPATIC VEINS): SEVEN CASES*EDDY D. PALMERCASE REPORT OF STENOSIS OF THE VENA CAVA WITH VENA CAVAL AND HEPATIC VEIN THROMBOSIS RELATED TO TRAUMA*RAYMOND D. LITTLE, M.D., P. O'B. MONTGOMERY, M.D.ENDOPHLEBITIS HEPATICA OBLITERANSChiari’s Syndrome 1 December 1940Volume 14, Issue 6Page: 1075-1083KeywordsAbscessesBiopsyBlood flowCirrhosisThrombosisVeins Issue Published: 1 December 1940 PDF DownloadLoading ...