tbuckley/cabot-search huggingface dataset:
Abstract PO-092: Influence of the IL-13-receptor alpha 1 chain on the malignant phenotype of pancreatic cancer cells
Authors: Jingwei Shi, Marko Kornmann, Benno Traub
Journal: Cancer Research (2021)

Abstract Introduction: Increasing evidence indicates salient activities of Interleukin (IL)-4, IL-13 and their specific Type-II-IL-4 receptor complex (IL-4Rα/IL-13Rα1) in carcinomas including pancreatic cancer. While IL-4 seems to be tumor-promoting in PDAC, the specific role of the IL-13/IL-13Rα1 axis was yet to be determined. Both cytokines are abundant in PDAC through cells of the tumor microenvironment. In this project, we planned to determine the specific effects of the IL-13Rα1-receptor chain on the malignant phenotype of pancreatic cancer cells. Methods: Expression of IL-13Rα1, IL-4Rα, and the human common gamma chain (γc) in cultured pancreatic cancer cell lines AsPC-1, Capan-1, PANC-1, MIA PaCa-2 and A818-6 as well as downstream signal transduction factors of IL13-Rα1 were detected by Western blot. The role of IL-13Rα1 in pancreatic cancer cell proliferation, mobility and migration was demonstrated based on the successful establishment of stable shRNA based IL-13Rα1-knockdown (KD) clones in Capan-1 and MIA PaCa-2 cell lines. Results: Not only the basal anchorage-dependent growth but also the anchorage-independent growth in soft agar were inhibited in Capan-1 and MIA PaCa-2 cells due to IL-13Rα1-downregulation. Mechanistically, IL-13Rα1-KD was associated with increased apoptosis. Additionally, signal transduction factors STAT3, STAT6, PI3K, Akt and ERK1/2 were activated in Capan-1 exposed to exogenous IL-4 and IL-13. Interestingly, IL-13Rα1-KD reduced the basal expression of STAT3, Akt and ERK1/2. IL-4 and IL-13 induced activation of STAT3, ERK1/2, Akt and STAT6 was significantly suppressed in Capan-1-IL-13Rα1-KD (C-KD) clones. Furthermore, IL-13Rα1-KD resulted in enhanced mobility and migration in Capan-1 cells. Conclusion: It was demonstrated that endogenous IL-13Rα1 is vital for pancreatic cancer cell growth with the involvement of STAT3/6, ERK1/2 and Akt. Surprisingly, IL-13Rα1-KD resulted in enhanced mobility and migration. Overall, IL-13Rα1 plays a critical but heterogenous role in PDAC. Our findings increase the understanding of the different functions and mechanisms involving IL-13Rα1 in pancreatic cancer progression. Citation Format: Jingwei Shi, Marko Kornmann, Benno Traub. Influence of the IL-13-receptor alpha 1 chain on the malignant phenotype of pancreatic cancer cells [abstract]. In: Proceedings of the AACR Virtual Special Conference on Pancreatic Cancer; 2021 Sep 29-30. Philadelphia (PA): AACR; Cancer Res 2021;81(22 Suppl):Abstract nr PO-092.
Nitric oxide releasing nanomatrix gel treatment inhibits venous intimal hyperplasia and improves vascular remodeling in a rodent arteriovenous fistula
Authors: Maheshika Somarathna, Patrick TJ. Hwang, Reid C. Millican, Grant C. Alexander, Tatyana Isayeva-Waldrop, Jennifer A. Sherwood, Brigitta C. Brott, Isabelle Falzon, Hannah Northrup, Yan-Ting Shiu, Chris J. Stubben, John Totenhagen, Ho-Wook Jun, Timmy Lee
Journal: Biomaterials (2021)

Vascular access is the lifeline for hemodialysis patients and the single most important component of the hemodialysis procedure. Arteriovenous fistula (AVF) is the preferred vascular access for hemodialysis patients, but nearly 60% of AVFs created fail to successfully mature due to early intimal hyperplasia development and poor outward remodeling. There are currently no therapies available to prevent AVF maturation failure. First, we showed the important regulatory role of nitric oxide (NO) on AVF development by demonstrating that intimal hyperplasia development was reduced in an overexpressed endothelial nitric oxide synthase (NOS3) mouse AVF model. This supported the rationale for the potential application of NO to the AVF. Thus, we developed a self-assembled NO releasing nanomatrix gel and applied it perivascularly at the arteriovenous anastomosis immediately following rat AVF creation to investigate its therapeutic effect on AVF development. We demonstrated that the NO releasing nanomatrix gel inhibited intimal hyperplasia formation (more than 70% reduction), as well as improved vascular outward remodeling (increased vein diameter) and hemodynamic adaptation (lower wall shear stress approaching the preoperative level and less vorticity). Therefore, direct application of the NO releasing nanomatrix gel to the AVF anastomosis immediately following AVF creation may enhance AVF development, thereby providing long-term and durable vascular access for hemodialysis.
Effects of Bypassing Hemostatic Agents in the Co-Presence of NXT007, Emicizumab-Based Engineered Bispecific Antibody to Fixa/Fx, Using in Vitro Global Assays: Rough Indicators for Their Concomitant Use
Authors: Kenichi Ogiwara, Shoko Furukawa, Kana Sasai, Keito Inaba, Takehisa Kitazawa, Keiji Nogami
Journal: Blood (2021)
Eosinophilic Myo-Pericarditis Presenting as Cardiac Tamponade
Authors: Salman Farhat, Mathew T Olson, Mohamad H Yamani
Journal: Clinical Cardiology and Cardiovascular Interventions (2019)

Eosinophilic myocarditis is a rare and acute life threatening condition often associated with drug reactions, eosinophilic granulomatous polyangiitis (formerly Churg-Strauss syndrome), Loeffler endomyocardial disease, parasite infections, and idiopathic hypereosinophilic syndrome. We describe a case of eosinophilic granulomatous polyangiitis presenting as progressive pericardial effusion and cardiac tamponade.
Tafasitamab Plus Lenalidomide Versus Pola-BR, R2, and CAR T: Comparing Outcomes from RE-MIND2, an Observational, Retrospective Cohort Study in Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Authors: Grzegorz S. Nowakowski, Dok Hyun Yoon, Patrizia Mondello, Erel Joffe, Isabelle Fleury, Anthea Peters, Richard Greil, Matthew Ku, Reinhard Marks, Kibum Kim, Pier Luigi Luigi Zinzani, Judith Trotman, Lorenzo Sabatelli, Dan Huang, Eva E. Waltl, Mark Winderlich, Sumeet Ambarkhane, Nuwan C. Kurukulasuriya, Raul Cordoba, Georg Hess, Gilles Salles
Journal: Blood (2021)
A Risk Score Incorporating Low Pass Whole Genome Sequencing of Cell Free DNA from Patients Receiving CD19 CAR T-Cell Therapy for Large B-Cell Lymphoma
Authors: Hua-Jay J. Cherng, Ryan Sun, Haopeng Yang, Qing Deng, Luis Fayad, Nathan H. Fowler, Simrit Parmar, Sairah Ahmed, Raphael E Steiner, Fredrick B. Hagemeister, Hun Ju Lee, Ranjit Nair, Maria Alma Rodriguez, Felipe Samaniego, Swaminathan P Iyer, Loretta Nastoupil, Sattva S. Neelapu, Paolo Strati, Jason R. Westin, Michael R Green
Journal: Blood (2021)
Multiparametric Magnetic Resonance Imaging for the Detection of Clinically Significant Prostate Cancer: What Urologists Need to Know. Part 4: Transperineal Magnetic Resonance–Ultrasound Fusion Guided Biopsy Using Local Anesthesia
Authors: Jos Immerzeel, Bas Israël, Joyce Bomers, Ivo G. Schoots, Jean-Paul van Basten, Karl-Heinz Kurth, Theo de Reijke, Michiel Sedelaar, Frans Debruyne, Jelle Barentsz
Journal: European Urology (2021)

Transperineal magnetic resonance imaging-transrectal ultrasound fusion guided biopsy (MFGB) is an increasingly popular technique due to increasing rates of biopsy-related infections. However, its widespread implementation has been hampered by the supposed necessity of epidural or general anesthesia.
Percutaneous femoral closure following thoracic aorta Stent graft placement: Preliminary results and 6 month follow up
Authors: Pablo Avanzas Fernández, María Martín Fernández, Alfonso Gerónimo Lozano Martínez-Luengas, José Manuel Llaneza Coto, Florentino Vega García, Félix Ezequiel Fernández Suárez, Jesús María de la Hera Galarza, José Miguel Vegas Valle, Juan José Rondán Murillo, José Benjamín Camacho Jiménez, José María Valle Castro, César Morís de la Tassa
Journal: Journal of the American College of Cardiology (2008)
Neither COVID-19, Nor Cryopreservation, Prevented Allogeneic Product Infusion: A Report from the National Marrow Donor Program
Authors: Heather E. Stefanski, Jeni Newman, Jennifer Novakovich, Jacklyn Barten, Jason Oakes, Meghann Cody, Huy P Pham, Jeffery Auletta, John P. Miller, Steven Devine
Journal: Blood (2021)
Lentiviral-Mediated Gene Therapy for the Treatment of Adenosine Deaminase 2 Deficiency
Authors: Alessandra Mortellaro, Matteo Zoccolillo, Cristina Mesa Nuñez, Alessia Brix, Immacolata Brigida, Federica Barzaghi, Serena Scala, Raisa Jofra Hernández, Luca Basso-Ricci, Mariasilvia Colantuoni, Simone Cesaro, Francesca Conti, Andrea Pession, Fabio Benedetti, Marco Gattorno, Luigi Naldini, Maria Pia Cicalese, Anna Pistocchi, Alessandro Aiuti
Journal: Blood (2021)
Safety and Efficacy of Ibrutinib Maintenance (I-M) Following Frontline Induction in Mantle Cell Lymphoma (MCL) with Sequential Assessment of Changes in NGS-MRD
Authors: Reem Karmali, Jeremy S. Abramson, Deborah M. Stephens, Jeffrey A Barnes, Jason Kaplan, Jane N. Winter, Shuo Ma, Juehua Gao, Adam M Petrich, Ephraim Hochberg, Tak Takvorian, Frank Kuhr, Lik Wee Lee, Valerie Nelson, Leo I. Gordon, Barbara Pro
Journal: Blood (2021)
Preliminary Results of a Phase II Study of Methotrexate in Combination with Ibrutinib and Temozolomide (MIT) in Newly Diagnosed Primary CNS Lymphoma
Authors: Xiaoxiao Wang, Yan Gao, Shanshan Yu, Bing Bai, Qiuxiang Ou, Liuqing Zhu, He Huang, Hui Zhou, Yang Shao, Linbo Cai, Hui-qiang Huang
Journal: Blood (2021)
Are current systems of global health academia fit for purpose?
Authors: Keerti Gedela
Journal: The Lancet Global Health (2021)

I read Himani Bhakuni and Seye Abimbola's Viewpoint1 with interest. Many of the epistemic injustices described relate to the institutional systems upheld to drive academic prestige in high-income settings, urging us to ask other questions. For example, are systems of global health academia of equal interest or significance across the globe? Arguably a divide exists in how relevant and important academic publication is to low-income and middle-income countries (LMICs) compared with high-income countries.
Epigenetic Drug Combination Alters Methylation Patterns in Patient-Derived Xenograft Models of <i>KMT2A</i>-Rearranged Pediatric AML Treated <i>In Vivo</i>
Authors: Anilkumar Gopalakrishnapillai, Erin Lynn Crowgey, Adam Marsh, E. Anders Kolb, Sonali P. Barwe
Journal: Blood (2021)
Effect of prophylactic endoscopic clip placement on clinically significant post-endoscopic mucosal resection bleeding in the right colon: a single-centre, randomised controlled trial
Authors: Sunil Gupta, Mayenaaz Sidhu, Neal Shahidi, Sergei Vosko, Owen McKay, Farzan Fahrtash Bahin, Simmi Zahid, Anthony Whitfield, Karen Byth, Gregor Brown, Eric Yong Tat Lee, Stephen John Williams, Nicholas Graeme Burgess, Michael John Bourke
Journal: The Lancet. Gastroenterology & hepatology (2021)
The Genomic Landscape of Waldenström Macroglobulinemia Reveals Sustained Germinal Center Activity and Late-Developing Copy Number Aberrations
Authors: Kylee H Maclachlan, Tina Bagratuni, Efstathios Kastritis, Bachisio Ziccheddu, Sydney X. Lu, Venkata D Yellapantula, Christopher Famulare, Benjamin Diamond, Monika Chojnacka, Arjun Raj, Emilia Mason, David G. Coffey, James E. Hoffman, Dickran Kazandjian, Andriy Derkach, Elli Papaemmanuil, Ahmet Dogan, Alexander Lesokhin, Ola Landgren, M. Lia Palomba, Francesco Maura, Meletios-Athanasios Dimopoulos
Journal: Blood (2021)
Abstract 9392: Cardiovascular, Metabolic and Safety Outcomes With Semaglutide by Age: A Post Hoc Analysis of SUSTAIN 6 and PIONEER 6
Authors: Mark Petrie, Stephen Bain, Soren Tetens Hoff, Nicklas Johansen, Søren Rasmussen, Tina Vilsboell, Mansoor Husain
Journal: Circulation (2021)

Introduction: For older patients with type 2 diabetes, treatments that minimize the risk of hypoglycemia and provide benefits in terms of comorbidities, while optimizing glycemic control, are parti...
Phase 2a Study of the Dual SYK/JAK Inhibitor Cerdulatinib (ALXN2075) As Monotherapy or in Combination with Rituximab in Patients with Relapsed/Refractory Follicular Lymphoma
Authors: Paul A. Hamlin, Manish R. Patel, Don Stevens, Brian T. Hess, Javier Munoz, Tatyana A. Feldman, Sonali M. Smith, Greg P. Coffey, Muhtarjan Osman, Jaymes S Holland, Cristina B Guzman, Stephen D. Smith
Journal: Blood (2021)
Treatment of pouchitis, Crohn's disease, cuffitis, and other inflammatory disorders of the pouch: consensus guidelines from the International Ileal Pouch Consortium
Authors: Bo Shen, Gursimran S Kochhar, David T Rubin, Sunanda V Kane, Udayakumar Navaneethan, Charles N Bernstein, Raymond K Cross, Akira Sugita, Jason Schairer, Ravi P Kiran, Philip Fleshner, James T McCormick, André D’Hoore, Samir A Shah, Francis A Farraye, Revital Kariv, Xiuli Liu, Joel Rosh, Shannon Chang, Ellen Scherl, David A Schwartz, Paulo Gustavo Kotze, David H Bruining, Jessica Philpott, Bincy Abraham, Jonathan Segal, Rocio Sedano, Maia Kayal, Stuart Bentley-Hibbert, Dino Tarabar, Sandra El-Hachem, Priya Sehgal, Joseph A Picoraro, Séverine Vermeire, William J Sandborn, Mark S Silverberg, Darrell S Pardi
Journal: The Lancet. Gastroenterology & hepatology (2021)
Soft Cervical Disk Herniation
Authors: C. D. Magill
Journal: JAMA (1974)

<h3>To the Editor.—</h3> I enjoyed reading the article by Drs. Lourie, Shende, and Stewart in the Oct 15 issue (226:302, 1973). I recall the case of a 70-year-old man whose main symptoms were incoordination and loss of balance, particularly when he rode in an airplane. But the symptoms also were worse when riding on any transportation device that might cause vibration. It turned out that the patient did have the syndrome described by Lourie et al, but all of his symptoms went away following a conservative treatment by cervical neck traction. In regard to technique, I prefer a combination of the Smith-Robinson and Cloward techniques, as described by Wiltberger (<i>Am J Surg</i>105:670, 1973). A bone plug is inserted anteriorly but does not reach the posterior longitudinal ligament. Most of the disk can be removed with pituitary forceps.
Nonmyeloablative Allogeneic Transplantation in First Remission for Philadelphia Chromosome-Negative B-Cell Acute Lymphoblastic Leukemia with Post-Transplantation Cyclophosphamide: Outcomes By Receipt of Pre-Transplant Blinatumomab
Authors: Jonathan Webster, B. Douglas Smith, Amy E. DeZern, Alexander J. Ambinder, Mark Levis, Margaret M. Showel, Gabrielle T. Prince, Lukasz P. Gondek, Gabriel Ghiaur, William Brian Dalton, Christopher S. Hourigan, Tania Jain, Douglas E Gladstone, Leo Luznik, Philip H. Imus, Javier Bolanos-Meade, Ephraim J. Fuchs, Christian B. Gocke, Abbas Abbas Ali, Carol Ann Huff, Ivan M. Borrello, Lode J. Swinnen, Nina D. Wagner-Johnston, Richard F. Ambinder, Richard J. Jones, Ivana Gojo
Journal: Blood (2021)
Resequencing of 388 cassava accessions identifies valuable loci and selection for variation in heterozygosity
Authors: Wei Hu, Changmian Ji, Zhe Liang, Jianqiu Ye, Wenjun Ou, Zehong Ding, Gang Zhou, Weiwei Tie, Yan Yan, Jinghao Yang, Liming Ma, Xiaoying Yang, Yunxie Wei, Zhiqiang Jin, Jianghui Xie, Ming Peng, Wenquan Wang, Anping Guo, Biyu Xu, Jianchun Guo, Songbi Chen, Mingcheng Wang, Yang Zhou, Xiaolong Li, Ruoxi Li, Xinhui Xiao, Zhongqing Wan, Feifei An, Jie Zhang, Qingyun Leng, Yin Li, Haitao Shi, Ray Ming, Kaimian Li
Journal: Genome biology (2021)

Abstract Background Heterozygous genomes are widespread in outcrossing and clonally propagated crops. However, the variation in heterozygosity underlying key agronomic traits and crop domestication remains largely unknown. Cassava is a staple crop in Africa and other tropical regions and has a highly heterozygous genome. Results We describe a genomic variation map from 388 resequenced genomes of cassava cultivars and wild accessions. We identify 52 loci for 23 agronomic traits through a genome-wide association study. Eighteen allelic variations in heterozygosity for nine candidate genes are significantly associated with seven key agronomic traits. We detect 81 selective sweeps with decreasing heterozygosity and nucleotide diversity, harboring 548 genes, which are enriched in multiple biological processes including growth, development, hormone metabolisms and responses, and immune-related processes. Artificial selection for decreased heterozygosity has contributed to the domestication of the large starchy storage root of cassava. Selection for homozygous GG allele in MeTIR1 during domestication contributes to increased starch content. Selection of homozygous AA allele in MeAHL17 is associated with increased storage root weight and cassava bacterial blight (CBB) susceptibility. We have verified the positive roles of MeTIR1 in increasing starch content and MeAHL17 in resistance to CBB by transient overexpression and silencing analysis. The allelic combinations in MeTIR1 and MeAHL17 may result in high starch content and resistance to CBB. Conclusions This study provides insights into allelic variation in heterozygosity associated with key agronomic traits and cassava domestication. It also offers valuable resources for the improvement of cassava and other highly heterozygous crops.
Abstract PO-104: Activation of WNT signaling in CD4+ T cells promotes immune suppression in pancreatic cancer
Authors: Wenting Du, Rosa E. Menjivar, Katelyn Donahue, Ashley Velez-Delgado, Marina Pasca di Magliano
Journal: Cancer Research (2021)

Abstract WNT ligand expression and activation of the WNT signaling have been associated with pancreatic ductal adenocarcinoma (PDA). Using a mouse model that recapitulates the stepwise progression of PDA, we previously showed that epithelial WNT signaling is required for PDA initiation and progression. Through single cell RNA sequencing, we discovered that, in addition to epithelial cells, infiltrating immune cells and in particular T cells express the WNT signaling machinery, including receptors, downstream effectors and target genes. In particular, T cells express high levels of Tcf7, encoding the transcription factor TCF1. TCF1 is important for T cell development, but its role in adult T cells and specifically in the setting of pancreatic cancer remained unknown. To address this, we generated mice that allow deletion of Tcf7 specifically in CD4+ T cells in an inducible manner. We then implanted orthotopic syngeneic tumors in control mice or in mice lacking Tcf7 in CD4+ T cells, and observed reduced tumor growth in the latter. Analysis of the tumors revealed an increase in apoptotic cells; while the prevalence of infiltrating T cells did not change, we observed an increase in cytotoxic marker expression, such as Granzyme B, consistent with increased T cell activation. We observed decreased regulatory T cells, possibly indicating less immune suppression. However, we also observed a compensatory infiltration of increased granulocytic myeloid derived suppressor cells. Deletion of Tcf7 in CD4+ T cells also re-polarized the immunosuppressive macrophages into pro-inflammatory macrophages, and alterations of inflammatory cytokines secreted by cancer associated fibroblasts. Taken together, this study reveals an important role of WNT signaling in CD4+ T cells in the PDA microenvironment. We are currently evaluating ways to exploit changes in the immune microenvironment upon inactivation of Tcf7 in CD4+ T cells in combination therapy approaches. Citation Format: Wenting Du, Rosa E. Menjivar, Katelyn Donahue, Ashley Velez-Delgado, Marina Pasca di Magliano. Activation of WNT signaling in CD4+ T cells promotes immune suppression in pancreatic cancer [abstract]. In: Proceedings of the AACR Virtual Special Conference on Pancreatic Cancer; 2021 Sep 29-30. Philadelphia (PA): AACR; Cancer Res 2021;81(22 Suppl):Abstract nr PO-104.
Association of Apolipoprotein B–Containing Lipoproteins and Risk of Myocardial Infarction in Individuals With and Without Atherosclerosis
Authors: Nicholas A. Marston, Robert P. Giugliano, Giorgio E. M. Melloni, Jeong-Gun Park, Valerie Morrill, Michael A. Blazing, Brian Ference, Evan Stein, Erik S. Stroes, Eugene Braunwald, Patrick T. Ellinor, Steven A. Lubitz, Christian T. Ruff, Marc S. Sabatine
Journal: JAMA Cardiology (2021)

Lipid management typically focuses on levels of low-density lipoprotein cholesterol (LDL-C) and, to a lesser extent, triglycerides (TG). However, animal models and genetic studies suggest that the atherogenic particle subpopulations (LDL and very-low-density lipoprotein [VLDL]) are both important and that the number of particles is more predictive of cardiac events than their lipid content.To determine whether common measures of cholesterol concentration, TG concentration, or their ratio are associated with cardiovascular risk beyond the number of apolipoprotein B (apoB)-containing lipoproteins.This prospective cohort analysis included individuals from the population-based UK Biobank and from 2 large international clinical trials, FOURIER and IMPROVE-IT. The median (IQR) follow-up was 11.1 (10.4-11.8) years in UK Biobank and 2.5 (2.0-4.7) years in the clinical trials. Two populations were studied in this analysis: 389 529 individuals in the primary prevention group who were not taking lipid-lowering therapy and 40 430 patients with established atherosclerosis who were receiving statin treatment.ApoB, non-high-density lipoprotein cholesterol (HDL-C), LDL-C, and TG.The primary study outcome was incident myocardial infarction (MI).Of the 389 529 individuals in the primary prevention group, 224 097 (58%) were female, and the median (IQR) age was 56.0 (49.5-62.5) years. Of the 40 430 patients with established atherosclerosis, 9647 (24%) were female, and the median (IQR) age was 63 (56.2-69.0) years. In the primary prevention cohort, apoB, non-HDL-C, and TG each individually were associated with incident MI. However, when assessed together, only apoB was associated (adjusted hazard ratio [aHR] per 1 SD, 1.27; 95% CI, 1.15-1.40; P < .001). Similarly, only apoB was associated with MI in the secondary prevention cohort. Adjusting for apoB, there was no association between the ratio of TG to LDL-C (a surrogate for the ratio of TG-rich lipoproteins to LDL) and risk of MI, implying that for a given concentration of apoB-containing lipoproteins, the relative proportions of particle subpopulations may no longer be a predictor of risk.In this cohort study, risk of MI was best captured by the number of apoB-containing lipoproteins, independent from lipid content (cholesterol or TG) or type of lipoprotein (LDL or TG-rich). This suggests that apoB may be the primary driver of atherosclerosis and that lowering the concentration of all apoB-containing lipoproteins should be the focus of therapeutic strategies.
Recombinant Porcine Factor VIII in Patients with Congenital Hemophilia a with Inhibitors Undergoing Surgery: Phase 3, Multicenter, Single Arm, Open-Label Study
Authors: Christian Pfrepper, Paolo Radossi, Jerzy Windyga, Kaan Kavakli, Roger E.G. Schutgens, Nazan Sarper, Jovanna Baptista, Kayode Badejo, Bruce Ewenstein, Nisha Jain
Journal: Blood (2021)
Compassionate Use of Belantamab Mafodotin for Treatment of Patients with Relapsed/Refractory Multiple Myeloma Heavily Treated. Spanish Experience
Authors: Adrian Alegre, Gonzalo Benzo Callejo, Rafael Alonso Fernández, Joaquin Martínez-López, Ana Jimenez-Ubieto, Clara Cuellar, Elham Askari, Elena Prieto, Concha Alaez, Beatriz Aguado, Alberto Velasco, Isabel Krsnik, Laura Llorente, Cristina Muñoz-Linares, Ana Morales, Eugenio Gimenez Mesa, Rebeca Iglesias, Carmen Martínez-Chamorro, Arancha Alonso, Carmen Jiménez-Montes, María Jesús Blanchard
Journal: Blood (2021)
<i>Treatment-Free Remissions in Newly Diagnosed CP CML Patients Treated with the Combination of Nilotinib + Pegylated Interferon Alpha 2a Versus Nilotinib Alone in the National Phase III Petals Trial</i>
Authors: Franck E. Nicolini, Gabriel Etienne, Francoise Huguet, Agnès Guerci-Bresler, Aude Charbonnier, Martine Escoffre-Barbe, Viviane Dubruille, Hyacinthe Johnson-Ansah, Laurence Legros, Valerie Coiteux, Pascale Cony-Makhoul, Pascal Lenain, Lydia Roy, Philippe Rousselot, Denis Guyotat, Jean-Christophe Ianotto, Corentin Orvain, Eric Deconinck, Denis Caillot, Pascal Turlure, Stephane Courby, Philippe Quittet, Eric Hermet, Shanti Amé, Simona Lapusan, Stephane Morisset, Francois-Xavier Mahon, Delphine Rea, Stephanie Dulucq
Journal: Blood (2021)