tbuckley/cabot-search huggingface dataset:
Invasive Tracheobronchial Aspergillosis in Critically Ill Patients with Severe Influenza. A Clinical Trial
Authors: Remy Nyga, Julien Maizel, Saad Nseir, Taieb Chouaki, Ivona Milic, Pierre-Alexandre Roger, Nicolas Van Grunderbeeck, Malcolm Lemyze, Anne Totet, Sandrine Castelain, Michel Slama, Hervé Dupont, Boualem Sendid, Elie Zogheib
Journal: American Journal of Respiratory and Critical Care Medicine (2020)

Rationale: Invasive tracheobronchial aspergillosis (ITBA) is an uncommon but severe clinical form of invasive pulmonary aspergillosis in which the fungal infection is entirely or predominantly confined to the tracheobronchial tree.Objectives: To analyze the diagnostic and prognostic differences between tracheobronchial aspergillosis and pulmonary aspergillosis without tracheobronchial lesions among patients admitted to the ICU with severe influenza.Methods: This retrospective, observational study included critically ill patients with influenza associated with pulmonary aspergillosis from three hospital ICUs between 2010 and 2019. Patient characteristics and clinical and mycologic data at admission and during ICU stay were collected in a database to evaluate variables in the two groups.Measurements and Main Results: Thirty-five patients admitted to the ICU with severe influenza and pulmonary aspergillosis were included. Ten patients were included in the group with ITBA (n = 10 of 35; 28.6%), and 25 patients were included in the group without ITBA. The group with ITBA comprised more patients with active smoking, diabetes mellitus, and higher severity scores (Simplified Acute Physiology Score II). Ninety-day mortality rates in the groups with and without ITBA were 90% and 44%, respectively (P = 0.02). Moreover, significantly higher serum 1,3-β-d-glucan and galactomannan and BAL fluid galactomannan concentrations were observed in the group with ITBA compared with the group without ITBA (P < 0.0001, P = 0.003, and P = 0.008, respectively).Conclusions: ITBA was associated with higher severity scores, mortality, and serum and BAL fluid galactomannan and 1,3-β-d-glucan concentrations than invasive pulmonary aspergillosis without tracheobronchial lesions. ITBA should be systematically researched by bronchoscopic examination in ICU patients with concomitant pulmonary aspergillosis and influenza.Clinical trial registered with www.clinicaltrials.gov (NCT04077697).
PREVENTION OF DELAYED BLEEDING AFTER ENDOSCOPIC PAPILLECTOMY: A RETROSPECTIVE STUDY
Authors: E Iwasaki, S Fukuhara, K Minami, S Kawasaki, H Tamagawa, Y Takimoto, Y Machida, M Noda, A Kayashima, M Kitago, H Ogata, T Kanai
Journal: Endoscopy (2020)

Background and Aim Endoscopic papillectomy is a minimally invasive therapy for duodenal ampullary adenoma. We evaluated clip closure method for the prevention of delayed bleeding retrospectively.
Hydroxychloroquine in patients with mainly mild to moderate coronavirus disease 2019: open label, randomised controlled trial
Authors: Wei Tang, Zhujun Cao, Mingfeng Han, Zhengyan Wang, Junwen Chen, Wenjin Sun, Yaojie Wu, Wei Xiao, Shengyong Liu, Erzhen Chen, Wei Chen, Xiongbiao Wang, Jiuyong Yang, Jun Lin, Qingxia Zhao, Youqin Yan, Zhibin Xie, Dan Li, Yaofeng Yang, Leshan Liu, Jieming Qu, Guang Ning, Guochao Shi, Qing Xie
Journal: BMJ (2020)

Abstract Objective To assess the efficacy and safety of hydroxychloroquine plus standard of care compared with standard of care alone in adults with coronavirus disease 2019 (covid-19). Design Multicentre, open label, randomised controlled trial. Setting 16 government designated covid-19 treatment centres in China, 11 to 29 February 2020. Participants 150 patients admitted to hospital with laboratory confirmed covid-19 were included in the intention to treat analysis (75 patients assigned to hydroxychloroquine plus standard of care, 75 to standard of care alone). Interventions Hydroxychloroquine administrated at a loading dose of 1200 mg daily for three days followed by a maintenance dose of 800 mg daily (total treatment duration: two or three weeks for patients with mild to moderate or severe disease, respectively). Main outcome measure Negative conversion of severe acute respiratory syndrome coronavirus 2 by 28 days, analysed according to the intention to treat principle. Adverse events were analysed in the safety population in which hydroxychloroquine recipients were participants who received at least one dose of hydroxychloroquine and hydroxychloroquine non-recipients were those managed with standard of care alone. Results Of 150 patients, 148 had mild to moderate disease and two had severe disease. The mean duration from symptom onset to randomisation was 16.6 (SD 10.5; range 3-41) days. A total of 109 (73%) patients (56 standard of care; 53 standard of care plus hydroxychloroquine) had negative conversion well before 28 days, and the remaining 41 (27%) patients (19 standard of care; 22 standard of care plus hydroxychloroquine) were censored as they did not reach negative conversion of virus. The probability of negative conversion by 28 days in the standard of care plus hydroxychloroquine group was 85.4% (95% confidence interval 73.8% to 93.8%), similar to that in the standard of care group (81.3%, 71.2% to 89.6%). The difference between groups was 4.1% (95% confidence interval –10.3% to 18.5%). In the safety population, adverse events were recorded in 7/80 (9%) hydroxychloroquine non-recipients and in 21/70 (30%) hydroxychloroquine recipients. The most common adverse event in the hydroxychloroquine recipients was diarrhoea, reported in 7/70 (10%) patients. Two hydroxychloroquine recipients reported serious adverse events. Conclusions Administration of hydroxychloroquine did not result in a significantly higher probability of negative conversion than standard of care alone in patients admitted to hospital with mainly persistent mild to moderate covid-19. Adverse events were higher in hydroxychloroquine recipients than in non-recipients. Trial registration ChiCTR2000029868.
‘Test, re-test, re-test’: using inaccurate tests to greatly increase the accuracy of COVID-19 testing
Authors: Kamalini Ramdas, Ara Darzi, Sanjay Jain
Journal: Nature Medicine (2020)

applicable recommendation would be to store separately in biobanks all human samples collected during the COVID-19 outbreak.Biobanks can identify whether they have an appropriate quality-assurance system in place and demonstrate to end users that this system is being applied, together with standard security guarantees.The quality-assurance system also enables the transparent traceability of the samples requested from academia and from bioindustry.Traceability ultimately allows assessment of the quality of the samples and associated data.However, this comes with financial investment.The present crisis represents a new, critical and urgent challenge in the field of biobanking for cancer research.
ENDOSCOPIC ULTRASOUND-GUIDED GALLBLADDER DRAINAGE AS RESCUE THERAPY IN A PATIENT WITH ADVANCED PANCREATIC NEOPLASIA AND SEVERE CHOLANGITIS
Authors: Gd Nucci, N Imperatore, E Mandelli, C Bezzio, B Omazzi, G Manes
Journal: Endoscopy (2020)

An 84-year-old female with an advanced pancreatic cancer underwent an ERCP and a fully covered metal stent was positioned just under the cystic duct insertion.Then an uncovered duodenal stent was placed. 3 months later she was hospitalized for severe cholangitis due to biliary stent occlusion and worsened duodenal infiltration. An EUS-guided drainage from the common bile duct such as a percutaneous one were not feasible. We performed an EUS-guided gallbladder drainage using an Hot AXIOS stent. The procedure was quick, safe and technically successful as a rescue therapy to treat a severe cholangitis in a patient with advanced pancreatic neoplasia.
MORTALITY OF ACUTE LOWER GASTROINTESTINAL BLEEDING: A PROSPECTIVE, MULTICENTRE, COHORT STUDY
Authors: A Andrealli, F Radaelli, L Frazzoni, A Repici, A Mussetto, C Spada, G Manes, S Segato, A Musso, ED Giulio, M Manno, GD Nucci, V Festa, AD Leo, M Marini, L Ferraris, C Hassan, L Fuccio, S Paggi
Journal: Endoscopy (2020)

Aims Acute lower GI bleeding (LGIB) is a common reason for hospitalization and death. This study was aimed to identify predictors of mortality in a large cohort of patients with acute LGIB.
BILIARY INTERVENTIONS IN PATIENTS WITH STERILE PANCREATIC AND PERIPANCREATIC NECROSIS INCREASE THE RISK FOR INFECTED COLLECTION
Authors: CR Simons-Linares, K Vantanasiri, V Chittajallu, A Sims, C Cuvillier, A Dirweesh, MA Saleh, T Stevens, C Martin, ML Freeman, G Trikudanathan, P Chahal
Journal: Endoscopy (2020)

Aims It is unclear if antecedent biliary interventions (BI) [ERCP, PHTC] performed for biliary obstruction pose risk of infecting evolving sterile pancreatic and or peripancreatic necrosis (PPN). We sought to determine if BIs increase the risk of infection in PPN patients.
反復性心室細動(electrical storm)がカテーテル焼灼術によって抑制された虚血性心筋症の一例
Authors: 柳沼憲志, 野上昭彦, 窪田彰一, 杉安愛子, 小和瀬晋弥, 有馬秀紀, 青木元, 柴祐司, 井川昌幸
Journal: Circulation (2004)
ENDOSCOPIC DUAL BILIARY DRAINAGE FOR UNRESECTABLE MALIGNANT HILAR BILIARY STRICTURES (WITH VIDEO)
Authors: T Koshitani, Y Konaka, T Ohishi, T Yasuda, T Morinushi, A Katsura, M Mita, S Nakagawa
Journal: Endoscopy (2020)

EUS-guided hepatogastrostomy (EUS-HGS) is an emerging technique of biliary decompression. We evaluated the efficacy of endoscopic dual biliary drainage using a combination of right-sided transpapillary stenting and left-sided EUS-HGS for unresectable malignant hilar biliary strictures (UMHBS). Three patients with high-grade UMHBS underwent endoscopic dual biliary drainage. Technical and clinical success rates were 3/3. Stent revisions were successfully performed via HGS route in all cases. The mean follow-up period was 180 days and stent patency was sustained in all the period with stent revision. Endoscopic dual biliary drainage may provide a possible chance of longer stent patency and easier stent revision.
ENDOSCOPIC MANAGEMENT OF NON-DIMINUTIVE POLYPS: OBSERVATIONS FROM THE EUROPEAN COLONOSCOPY QUALITY INVESTIGATION QUESTIONNAIRE
Authors: P Amaro, A Agrawal, L Brink, W Fischbach, L Fuccio, M Hünger, U Kinnunen, A Koulaouzidis, A Ono, L Petruzziello, E Toth, JF Riemann, B Amlani, C Spada
Journal: Endoscopy (2020)

Aims To assess the endoscopic interventions performed in procedures where a non-diminutive polyp was recorded.
Nonalcoholic fatty liver disease in CLOCK mutant mice
Authors: Xiaoyue Pan, Joyce Queiroz, M. Mahmood Hussain
Journal: Journal of Clinical Investigation (2020)

Nonalcoholic fatty liver disease (NAFLD) is becoming a major health issue as obesity increases around the world. We studied the effect of a circadian locomotor output cycles kaput (CLOCK) mutant (ClkΔ19/Δ19) protein on hepatic lipid metabolism in C57BL/6 Clkwt/wt and apolipoprotein E-deficient (Apoe-/-) mice. Both ClkΔ19/Δ19 and ClkΔ19/Δ19 Apoe-/- mice developed a full spectrum of liver diseases (steatosis, steatohepatitis, cirrhosis, and hepatocellular carcinoma) recognized in human NAFLD when challenged with a Western diet, lipopolysaccharide, or CoCl2. We identified induction of CD36 and hypoxia-inducible factor 1α (HIF1α) proteins as contributing factors for NAFLD. Mechanistic studies showed that WT CLOCK protein interacted with the E-box enhancer elements in the promoters of the proline hydroxylase domain (PHD) proteins to increase expression. In ClkΔ19/Δ19 mice, PHD levels were low, and HIF1α protein levels were increased. When its levels were high, HIF1α interacted with the Cd36 promoter to augment expression and enhance fatty acid uptake. Thus, these studies establish a regulatory link among circadian rhythms, hypoxia response, fatty acid uptake, and NAFLD. The mouse models described here may be useful for further mechanistic studies in the progression of liver diseases and in the discovery of drugs for the treatment of these disorders.
MEK1/2 blockade by AZD6244 (ARRY-142886) inhibits tumor growth and progression in an orthotopic human lung adenocarcinoma model with enhanced efficacy when combined with cediranib
Authors: O Takahashi, R Komaki, P D Smith, A Ryan, J M Jurgensmeier, J W Welsh, J J Jacoby, K Hosho, M Korshunova, B Erez
Journal: Journal of Thoracic Oncology (2009)
HAS COLONOSCOPY WITHDRAWAL TIME CHANGED SINCE THE INTRODUCTION OF NATIONAL ENDOSCOPY DATABASE REPORTING SOFTWARE?
Authors: MG Shiha, A Al-Rifaie, M Thoufeeq
Journal: Endoscopy (2020)

Aims Colonoscopy withdrawal time (CWT) is a core quality indicator affecting Adenoma detection rate (ADR) and subsequently preventing colorectal cancer. however, Studies have shown wide variation in CWT and ADR between different endoscopists. The National Endoscopy Database (NED) was implemented to ensure quality in all endoscopy units across the UK and also to avoid variation in practice. Our aim is to assess whether CWT changed since the introduction of NED compliant endoscopy reporting software (ERS) and whether CWT affected ADR.
ORAL INGESTION VS ENDOSCOPIC PLACEMENT OF ENDOSCOPIC CAPSULE IN PATIENTS WITH PREVIOUS GASTROINTESTINAL SURGERY (ORENCES): A SPANISH MULTICENTER OBSERVATIONAL STUDY
Authors: A Giordano, AE González, FS Ceballos, CC Ribón, M Aicart-Ramos, J Egea-Valenzuela, N Alonso-Lázaro, JLM Lorente, CG Castillo, IFU Sainz, B González-Suárez
Journal: Endoscopy (2020)

Aims Capsule endoscopy (CE) represents the first-choice technique to investigate the majority of small bowel diseases. Its most common complications are related to incomplete examinations and capsule retention. There is no agreement on how patients with previous gastrointestinal (GI) surgery should receive the capsule.
VEGF SIGNALING INHIBITION BY CEDIRANIB ENHANCES THE ANTITUMOR AND ANTI-METASTATIC EFFECTS OF RADIATION THERAPY MORE SUBSTANTIALLY THAN PACLITAXEL IN A MURINE ORTHOTOPIC MODEL OF LUNG CANCER
Authors: O Takahashi, R Komaki, J M Juergensmeier, A J Ryan, P D Smith, I I Wistuba, B N Bekele, R C Tailor, J J Jacoby, M V Korshunova
Journal: Journal of Thoracic Oncology (2011)
In irritable bowel syndrome, fecal microbiota transplantation improved symptoms at 3 months
Authors: Nicholas J. Talley, Mudar Irani
Journal: Annals of Internal Medicine (2020)

El-Salhy M, Hatlebakk JG, Gilja OH, Bråthen Kristoffersen A, Hausken T. Efficacy of faecal microbiota transplantation for patients with irritable bowel syndrome in a randomised, double-blind, placebo-controlled study. Gut. 2020;69:859-67. 31852769.
AGGRESSIVE HYDRATION FOR PREVENTING POST ERCP PANCREATITIS: A SYSTEMATIC REVIEW AND META-ANALYSIS
Authors: A Tringali, E Piovesana, F Pozzato, A Graziotto, M Rinaldi, D Adler
Journal: Endoscopy (2020)

Aims Periprocedural intravenous hydration is suggested to decrease the risk of post-ERCP pancreatitis (PEP). However, quality of evidence remains poor. We performed a systematic review with meta-analysis to assess the hypothesis that aggressive hydration(AH) could be an effective preventive measure.
Tuberculosis associated with Triplet therapy for lung cancer
Authors: Danielle Crawley, Ronan A Breen, Paul T Elkington, Eleni Karapanagiotou
Journal: Thorax (2020)

We report the first case of TB associated with triplet therapy (chemotherapy and immunotherapy concurrently) for lung cancer, developing just 44 days after treatment initiation. We feel that several important learning points arise from the discussion that are likely to be very relevant to the broad readership of Thorax , and have important clinical and scientific implications. In the three discussion paragraphs, we highlight that: 1) Triplet therapy is now standard first-line treatment for inoperable lung cancer. 2) TB reactivation is increasingly recognised as an adverse effect of immune checkpoint inhibition, but sending diagnostic samples is critical to avoid a missed diagnosis. 3) These insights from novel cancer immunotherapies are challenging the traditional views of the host-pathogen interaction in TB, with wide implications for future control strategies. We propose that the cases reported in the literature are likely to be the tip of the iceberg as most people with lung cancer managed with antiprogrammed death-1 agents who develop new lung lesions will be treated with standard antibiotics and then palliated when they do not respond.
Feasibility of Integration of Resident Surgical Evaluations Into the Electronic Medical Record
Authors: Elaine Stickrath, Karilynn Rockhill, Heather Zuhn, Meredith J. Alston
Journal: JAMA Surgery (2020)

This cohort study of resident physicians and faculty members at a single academic center examines the usability and acceptability of a resident evaluation tool integrated into an electronic medical records system.
Acute Illness Associated With Cannabis Use, by Route of Exposure
Authors: Andrew A. Monte, Shelby K. Shelton, Eleanor Mills, Jessica Saben, Andrew Hopkinson, Brandon Sonn, Michael Devivo, Tae Chang, Jacob Fox, Cody Brevik, Kayla Williamson, Diana Abbott
Journal: Annals of Internal Medicine (2019)

Little is known about acute illness due to use of cannabis products. This study compares symptoms, diagnoses, and outcomes in adults who had emergency department visits related to edible or inhaled...
MANAGEMENT OF CHRONIC RADIATION PROCTOPATHY: A SINGLE CENTRE 12 YEARS’ EXPERIENCE WITH ARGON PLASMA COAGULATION
Authors: M João, S Alves, M Areia, F Taveira, L Elvas, D Brito, S Saraiva, AT Cadime
Journal: Endoscopy (2020)

Aims Chronic radiation proctopathy (CRP) is a recognised complication of pelvic radiotherapy, but no standard treatment has been established. The aims of this study were to define the natural history of CRP and to evaluate and compare efficacy of chosen therapies.
Catheter Ablation for Atrial Fibrillation with Heart Failure
Authors: Paulino Alvarez, Aref Bin Abdulhak, James Torner
Journal: New England Journal of Medicine (2018)

the Editor: In the Catheter Ablation versus Standard Conventional Therapy in Patients with Left Ventricular Dysfunction and Atrial Fibrillation (CASTLE-AF) trial, Marrouche et al. (Feb. 1 issue) 1 found a 46% lower rate of death from any cause among patients who were randomly assigned to catheter ablation than among those who were assigned to medical therapy.One concern in interpreting these results is that the patients underwent randomization before the run-in phase. 2,3uring the run-in phase, 18 patients in the ablation group and 9 in the medical-therapy group were excluded.This process may have affected patient assignments and subverted randomization.Consequent imbalances that may have had an effect on the primary end point include a significantly higher proportion of patients in the medical-therapy group than in the ablation group who had a diagnosis of ischemic cardiomyopathy, who had diabetes mellitus, and who were receiving digoxin at baseline.Ischemic heart disease, diabetes, and a high serum digoxin concentration have all been associated with increased mortality, and no data regarding digoxin dosing or monitoring were reported in the article. 4,5 Although ischemic heart disease and digoxin therapy are known confounding factors, the possibility of imbalances of unknown confounding factors cannot be ruled out.
HIGH CLEANSING EFFICACY WITH OVERNIGHT SPLIT DOSING 1 L NER1006 ACROSS BODY MASS INDEX RANGES: POST HOC ANALYSIS OF TWO RANDOMISED PHASE 3 CLINICAL TRIALS
Authors: J Manning, J Halonen, MA Alvarez-Gonzalez
Journal: Endoscopy (2020)

Aims We compared, per body mass index (BMI) range, the cleansing performance of 1 L polyethylene glycol NER1006 (PLENVU) versus two preparations.
Abstract 14649: Use of Tumor Necrosis Factor Alpha Inhibitors for Treatment of Refractory Cardiac Sarcoidosis
Authors: Alison L Wand, David Okada, Jan M Griffin, Harikrishna S Tandri, Jonathan Chrispin, Farooq H Sheikh, Edward K Kasper, Edward Chen, Nisha A Gilotra
Journal: Circulation (2019)

Introduction: Cardiac sarcoidosis (CS) is an important cause of cardiomyopathy and arrhythmia. Treatment is limited by corticosteroid side effects and variable efficacy of steroid sparing agents (S...
A COMMON BILE DUCT (CBD) STONE FORMED AROUND A SUTURE MATERIAL AFTER OPEN CHOLECYSTECTOMY: A CASE REPORT
Authors: O Labianca, F Esposito, L Martorelli, F Pirozzi, C Zulli, A Maurano
Journal: Endoscopy (2020)

Aims Among the numerous and various known predisposing factors, has been shown that the use of non-absorbable suture materials in hepatobiliary surgery, can expose patients to the risk of iatrogenic stones formation in the CBD. We described a rare case of CBD stone formation around a migrated nidus of non-absorbable prolene suture, after open cholecystectomy.
ENDOSCOPIC RESECTION BY STER OF GASTRIC GIST OF THE MUSCULAR PROPIA
Authors: P Roson, F Cano, A Ortega, A Garcia, MA Romero, M Puya, J Cotta
Journal: Endoscopy (2020)

GISTs are potentially aggressive tumors that metastasize to the liver, peritoneum or lung in 38% of patients.
Personalized iPSC-Derived Dopamine Progenitor Cells for Parkinson’s Disease
Authors: Jeffrey S. Schweitzer, Bin Song, Todd M. Herrington, Tae-Yoon Park, Nayeon Lee, Sanghyeok Ko, Jeha Jeon, Young Cha, Kyungsang Kim, Quanzheng Li, Claire Henchcliffe, Michael Kaplitt, Carolyn Neff, Otto Rapalino, Hyemyung Seo, In-Hee Lee, Jisun Kim, Taewoo Kim, Gregory A. Petsko, Jerome Ritz, Bruce M. Cohen, Sek-Won Kong, Pierre Leblanc, Bob S. Carter, Kwang-Soo Kim
Journal: New England Journal of Medicine (2020)

We report the implantation of patient-derived midbrain dopaminergic progenitor cells, differentiated in vitro from autologous induced pluripotent stem cells (iPSCs), in a patient with idiopathic Parkinson's disease. The patient-specific progenitor cells were produced under Good Manufacturing Practice conditions and characterized as having the phenotypic properties of substantia nigra pars compacta neurons; testing in a humanized mouse model (involving peripheral-blood mononuclear cells) indicated an absence of immunogenicity to these cells. The cells were implanted into the putamen (left hemisphere followed by right hemisphere, 6 months apart) of a patient with Parkinson's disease, without the need for immunosuppression. Positron-emission tomography with the use of fluorine-18-L-dihydroxyphenylalanine suggested graft survival. Clinical measures of symptoms of Parkinson's disease after surgery stabilized or improved at 18 to 24 months after implantation. (Funded by the National Institutes of Health and others.).
Tracheostomy in the COVID-19 era: global and multidisciplinary guidance
Authors: Brendan A McGrath, Michael J Brenner, Stephen J Warrillow, Vinciya Pandian, Asit Arora, Tanis S Cameron, José Manuel Añon, Gonzalo Hernández Martínez, Robert D Truog, Susan D Block, Grace C Y Lui, Christine McDonald, Christopher H Rassekh, Joshua Atkins, Li Qiang, Sébastien Vergez, Pavel Dulguerov, Johannes Zenk, Massimo Antonelli, Paolo Pelosi, Brian K Walsh, Erin Ward, You Shang, Stefano Gasparini, Abele Donati, Mervyn Singer, Peter J M Openshaw, Neil Tolley, Howard Markel, David J Feller-Kopman
Journal: The Lancet Respiratory Medicine (2020)
MASSIVE HEMORRHAGE AFTER ENDOSCOPIC ULTRASOUND GUIDED FINE NEEDLE ASPIRATION OF A CEPHALOPANCREATIC CYSTIC LESION
Authors: P Costa-Moreira, P Moutinho-Ribeiro, G Macedo
Journal: Endoscopy (2020)

A 68 years-old female was referred for endoscopic ultrasound study of a cephalopancreatic cystic lesion. A 22 G FNA was performed under ultrasound and Doppler guidance. After needle removal, a high-velocity and pulsatile hemorrhage was detected in the puncture site of the duodenal wall. Using the echoendoscope, we performed adrenaline (0.0001%) injection and applied two clips, with a partial control. We opted for switching to a gastroscope, complementing the hemostatic therapy with three more clips and injection of 2 mL of polidocanol (2%). The patient remained stable and was discharged after 72 hours of clinical vigilance.