tbuckley/cabot-search huggingface dataset:
Rapid Turnover of Hepatitis B Virus Covalently Closed Circular DNA Indicated by Monitoring Emergence and Reversion of Signature‐Mutation in Treated Chronic Hepatitis B Patients
Authors: Qi Huang, Bin Zhou, Dawei Cai, Yuhua Zong, Yaobo Wu, Shi Liu, Alexandre Mercier, Haitao Guo, Jinlin Hou, Richard Colonno, Jian Sun
Journal: Hepatology (2020)

Background and Aims Hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) plays a pivotal role in the establishment and persistence of HBV infection. Understanding the turnover time of preexisting cccDNA pools would be helpful in designing strategies to clear HBV by fully blocking the de novo generation of cccDNA. Approach and Results In this study, we retrospectively monitored the emergence and reversion of the rtM204I/V mutant, a signature lamivudine resistance (LAM R ) mutation serving as a biomarker of cccDNA turnover in liver biopsies and longitudinal serum samples from two clinical trials. Methodologies were optimized to differentially isolate and sequence HBV virion DNA, cccDNA, and HBV RNA from clinical samples. A strong correlation was observed between LAM R composition of cccDNA with that of serum and intrahepatic HBV RNA in paired liver and serum samples (r = 0.96 and 0.90, respectively), suggesting that serum HBV RNA can serve as a surrogate marker of cccDNA genetic composition when liver biopsies are unavailable. LAM R mutations emerged and increased from undetectable to 40%‐90% within 16‐28 weeks in serum HBV RNA from telbivudine‐treated patients experiencing virological breakthrough. Similarly, in lamivudine‐resistant patients who switched to interferon therapy, serum HBV‐RNA population bearing 100% LAM R mutations fully reversed back to wild type within 24‐48 weeks. Conclusions The genetic composition dynamics of serum HBV RNA and biopsy cccDNA in treated HBV patients indicates that cccDNA turnover occurs relatively rapidly (several months), offering a possibility of HBV cure with finite therapy through completely blocking cccDNA replenishment.
Health Care Is a Right and Not a Privilege
Authors: Howard Bauchner, Phil B. Fontanarosa
Journal: JAMA (2020)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
PROGNOSTIC VALUE OF LUNG ULTRASOUND AFTER HOSPITALIZATION FOR ACUTE HEART FAILURE BEYOND THE CLINICAL RISK SCORES
Authors: Jesus Alvarez-Garcia, Mercedes Rivas-Lasarte, Juan Fernandez Martinez, Alba Maestro Benedicto, Laura Lopez Lopez, Sonia Mirabet Perez, Vicens Brossa, Maria Jose Pirla, Nuria Mesado, Juan Cinca, Eulalia Roig, Alessandro Sionis Green
Journal: Journal of the American College of Cardiology (2020)
Serological and molecular findings during SARS-CoV-2 infection: the first case study in Finland, January to February 2020
Authors: Anu Haveri, Teemu Smura, Suvi Kuivanen, Pamela Österlund, Jussi Hepojoki, Niina Ikonen, Marjaana Pitkäpaasi, Soile Blomqvist, Esa Rönkkö, Anu Kantele, Tomas Strandin, Hannimari Kallio-Kokko, Laura Mannonen, Maija Lappalainen, Markku Broas, Miao Jiang, Lotta Siira, Mika Salminen, Taneli Puumalainen, Jussi Sane, Merit Melin, Olli Vapalahti, Carita Savolainen-Kopra
Journal: Eurosurveillance (2020)

The first case of coronavirus disease (COVID-19) in Finland was confirmed on 29 January 2020. No secondary cases were detected. We describe the clinical picture and laboratory findings 3-23 days since the first symptoms. The SARS-CoV-2/Finland/1/2020 virus strain was isolated, the genome showing a single nucleotide substitution to the reference strain from Wuhan. Neutralising antibody response appeared within 9 days along with specific IgM and IgG response, targeting particularly nucleocapsid and spike proteins.
THE MAN WITH NO PULSE: A CASE OF PERMANENT VENTRICULAR FIBRILLATION
Authors: Peter Unkovic, Jeremy Slivnick, Kristopher Kline, Brent Lampert, Rami Kahwash, Veronica Franco, Garrie Haas, Ragavendra Baliga, Sakima Ahmad Smith, Ayesha K. Hasan
Journal: Journal of the American College of Cardiology (2020)
DOUBLE TROUBLE: CARDIOGENIC SHOCK SECONDARY TO SEVERE AORTIC VALVE INSUFFICIENCY ACROSS A BICUSPID VALVE AND SEVERE MITRAL VALVE REGURGITATION
Authors: Sanchita Singal Parulkar, Kashif Ather, Neel Sodha, Daniel Levine, Athena Poppas, Eirini Apostolidou
Journal: Journal of the American College of Cardiology (2020)
INVESTIGATING THE EFFECT OF EDUCATION LEVEL ON ADHERENCE TO NUTRITIONAL GUIDELINES IN CARDIAC REHABILITATION PATIENTS
Authors: Suzanne Irani, Ahana Raina, Nicole Souphis, Spencer Morgan, Rumi Deb, Samantha Fink, Joe Bryant, Xiaowen Kong, Eva M. Kline-Rogers, Melvyn Rubenfire
Journal: Journal of the American College of Cardiology (2020)
ASSOCIATION BETWEEN BIVENTRICULAR MECHANICAL PATTERN AND EXERCISE CAPACITY IN ATHLETES: MACHINE LEARNING BASED PREDICTION OF PEAK OXYGEN UPTAKE
Authors: Marton Tokodi, Bálint Károly Lakatos, Zoltán Tősér, Máté Csákvári, Alexandra Fábián, Máté Babity, Csaba Bognár, Nóra Sydó, Hajnalka Vágó, Orsolya Kiss, Béla Merkely, Attila Kovács
Journal: Journal of the American College of Cardiology (2020)
CLOPIDOGREL VERSUS TICAGRELOR AND PRASUGREL IN PRIMARY PERCUTANEOUS CORONARY INTERVENTION PATIENTS WITH A NORMAL FUNCTION CYP2C19 GENE: A SUB-STUDY FROM THE POPULAR GENETICS
Authors: Daniel Claassens, Thomas Bergmeijer, Gerrit J.A. Vos, Rik S. Hermanides, Arnoud Hof, Pim van der Harst, Emanuele Barbato, Carmine Morisco, Richard M. Tjon Joe Gin, Folkert Asselbergs, Arend Mosterd, Jean-Paul Herrman, Willem J.M. Dewilde, Vera H.M. Deneer, Jurrien M. Ten Berg
Journal: Journal of the American College of Cardiology (2020)
<sup>18</sup>f-FDG-PET imaging as an early survival predictor in patients with high-grade soft tissue sarcomas undergoing neoadjuvant therapy.
Authors: Ken Herrmann, Matthias R. Benz, Johannes Czernin, Martin Auerbach, William D. Tap, Sarah M Dry, Tibor Schuster, Jeff J. Eckardt, Michael E. Phelps, Frederick C. Eilber
Journal: Journal of Clinical Oncology (2012)

10012 Background: Neoadjuvant therapy is associated with considerable toxicity and limited survival benefits in patients with soft tissue sarcoma (STS). We prospectively evaluated whether 18 F-FDG PET/CT (PET) imaging after the initial cycle and after end of neoadjuvant therapy could predict overall survival in these patients. Methods: 76 patients (primary STS: n=57; metastatic disease: n=19) with high grade STS were included in this study. PET was performed prior to (n=76), after one cycle (n=52) and after the end of neoadjuvant therapy (n=74). Overall survival was correlated with changes of SUVpeak, RECIST, histopathological response and other parameters predictive of STS survival. Results: One-, two- and five- year survival rates were 95±3.0%, 86±4.6% and 68±6.6% for primary STS. Corresponding one- and two- year survival rates for recurrent/metastatic STS were 77±10.0% and 47±12.1%. Optimal cut-off for early decreases in SUV peak were significant predictors of survival in log-rank test (p=0.027 and p=0.043). However, late decreases in SUV peak were only predictive in primary STS (SUV peak decrease 57%; p=0.035) but not in recurrent/metastatic STS (SUV peak decrease 52%; p=0.057). In primary STS, 7/15 early PET non-responders but only 4/24 early PET responders died during follow up (p=0.068). Conclusions: 18 F-FDG-PET seems feasible to predict survival after the initial cycle of neoadjuvant chemotherapy in both patients with primary STS and recurrent/metastatic STS and can potentially serve as an intermediate endpoint biomarker in clinical research and patient care.
RISK FACTORS FOR CORONARY ARTERY CALCIUM INCIDENCE AND PROGRESSION IN AN ETHNICALLY DIVERSE COHORT
Authors: Rhanderson Cardoso, Giuliano Generoso, Henrique Staniak, Murilo Foppa, Bruce Duncan, Alexandre Pereira, Michael Blaha, Ron Blankstein, Khurram Nasir, Isabela Bensenor, Paulo Lotufo, Marcio Bittencourt
Journal: Journal of the American College of Cardiology (2020)
Limited Clinical Application and Concerns of Bias in Long-term Risk of Epilepsy, Psychiatric Disorders, and Mortality Following Febrile Seizures
Authors: Jakob Bie Granild-Jensen, Niels Bjerregaard Matthiesen, John R. Østergaard
Journal: JAMA Pediatrics (2020)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Pediatrics HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Pediatrics journal
TOO MUCH CALCIUM: PRIMARY HYPERPARATHYROIDISM PRECIPITATING OBSTRUCTION IN HYPERTROPHIC CARDIOMYOPATHY
Authors: Lekha Racharla, Soorya Aggarwal, John DallaRosa, Kailyn Mann, Tarick Sheikh, Tyler Boozel, Preysi Patel, Sagar Vadhar, Larry E. Jacobs
Journal: Journal of the American College of Cardiology (2020)
42P The establishment of a large tumor organoid biobank using a well characterized/annotated patient-derived xenograft (PDX) library to enable drug discovery and translational research
Authors: L. Bourre, X. Xu, L. Shang, L. Wang, C. Li, Y. Liu, P. Han, Z. Sun, Y. Qu, L. Zhang, B. Chen, D. Ouyang, Y. Huang, H. Li
Journal: Annals of Oncology (2020)
DOES HEMODIALYSIS IMPACT ACUTE CORONARY SYNDROME MANAGEMENT IN END-STAGE RENAL DISEASE PATIENTS: A 5 YEAR NATIONWIDE ANALYSIS
Authors: Claire Huang Lucas, Robert Abed, Jan Lopes, Lingling Wu, Ameesh Isath, Bing Yue, Xin Wei, Eyal Herzog
Journal: Journal of the American College of Cardiology (2020)
Small-Cell Carcinoma of the Ovary, Hypercalcemic Type–Genetics, New Treatment Targets, and Current Management Guidelines
Authors: Marc Tischkowitz, Sidong Huang, Susana Banerjee, Jennifer Hague, William P.D. Hendricks, David G. Huntsman, Jessica D. Lang, Krystal A. Orlando, Amit M. Oza, Patricia Pautier, Isabelle Ray-Coquard, Jeffrey M. Trent, Michael Witcher, Leora Witkowski, W. Glenn McCluggage, Douglas A. Levine, William D. Foulkes, Bernard E. Weissman
Journal: Clinical Cancer Research (2020)

Small-cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is a rare and highly aggressive ovarian malignancy. In almost all cases, it is associated with somatic and often germline pathogenic variants in SMARCA4, which encodes for the SMARCA4 protein (BRG1), a subunit of the SWI/SNF chromatin remodeling complex. Approximately 20% of human cancers possess pathogenic variants in at least one SWI/SNF subunit. Because of their role in regulating many important cellular processes including transcriptional control, DNA repair, differentiation, cell division, and DNA replication, SWI/SNF complexes with mutant subunits are thought to contribute to cancer initiation and progression. Fewer than 500 cases of SCCOHT have been reported in the literature and approximately 60% are associated with hypercalcemia. SCCOHT primarily affects females under 40 years of age who usually present with symptoms related to a pelvic mass. SCCOHT is an aggressive cancer, with long-term survival rates of 30% in early-stage cases. Although various treatment approaches have been proposed, there is no consensus on surveillance and therapeutic strategy. An international group of multidisciplinary clinicians and researchers recently formed the International SCCOHT Consortium to evaluate current knowledge and propose consensus surveillance and therapeutic recommendations, with the aim of improving outcomes. Here, we present an overview of the genetics of this cancer, provide updates on new treatment targets, and propose management guidelines for this challenging cancer.
The analyses of disease free survival and overall survival in premenopausal and postmenopausal axillary node negative breast cancer patients
Authors: N. D. Bajic, D. D. Scepanovic
Journal: Journal of Clinical Oncology (2006)

10757 Background: The aim of this study was to analyse in which order known traditional prognostic factors predict disease free survival (DFS) and overall survival (OS) in breast cancer patients (pts) who are patohystologicaly axillary node negative. Methods: From 1998 till 2004, 258 patients were treated of axillary node negative breast cancer. We analysed 3 and 5 years (yrs) DFS and 3 and 5 yrs OS for all patients as well as for premenopausal (96 pts, 37%) and postmenopausal (162 pts, 63%). The mean follow-up time for DFS was 60 months (mo) (min 30, max 136 mo) and for OS was 66 mo (min 36, max 140 mo). As prognostic factors for DFS and OS, age, tumour size, HG as well as adjuvant treatment (locoregional and systemic) were analysed accordingly. Fifty two patients (20%) were HG1 while 190 pts (74%), were HG2 &amp; 3; 30 pts (11%) had tumour up to 1cm and 157 pts (61%) had tumours up to 3cm and 71 pts (28%) above 3cm. Radical mastectomy was performed in 92 pts (36%) while conservative surgery were performed in 166 pts (64%). Systemic therapy was applied in 224 pts (87% of which 57% were treated with hormonotherapy). Results: 3 yrs DFS for 258 treated pts were 87% - there was no statistically significant difference among pre- and postmenopausal pts; 5 yrs DFS were 73% with no statistically significant difference among pre- and postmenopausal group of pts (p &gt; 0.05). 3 yrs overall survival were 94% and 5 yrs 80% with no statistically significant difference among pre- and postmenopausal pts (p &gt; 0.05). There were statistically different DFS and OS among those pts treated with adjuvant radiotherapy as well as for those with adjuvant systemic therapy in both group of pts (p &lt; 0.001). Also as independent prognostic factor for DFS and OS were HG (Cox regression model). Conclusions: Although, HG and adjuvant therapy are the most important prognostic factors for DFS and OS in premenopausal and postmenopausal patients, we found that there is no statistically significant difference between the groups respectively. However, life-expectancy for premenopausal patients is longer. Therefore further adjuvant therapy research is needed to achieve better DFS and OS in this group of pts. No significant financial relationships to disclose.
Severe underquantification of HIV-1 group O isolates by major commercial PCR-based assays
Authors: A. Berger, M. Muenchhoff, K. Hourfar, M. Kortenbusch, I. Ambiel, L. Stegmann, A. Heim, C. Sarrazin, R. Ehret, V. Daniel, M. Wasner, J.-C. Plantier, J. Eberle, L. Gürtler, A.E. Haberl, M. Stürmer, O.T. Keppler
Journal: Clinical Microbiology and Infection (2020)
DISCHARGE DISPOSITION AND READMISSION FOR PATIENTS TREATED FOR CARDIOGENIC SHOCK
Authors: Carolyn Rosner, Behnam Tehrani, Alexander George Truesdell, Abdulla Damluji, Kelly Epps, Shashank Sinha, Karl Young, Anika Raja, Scott Barnett, Christopher R. DeFilippi, Shashank Desai, Charles Murphy, Christopher O'Connor, Wayne B. Batchelor
Journal: Journal of the American College of Cardiology (2020)
Factors predicting local recurrence in phyllodes tumor of the breast.
Authors: Pooja Ramakant, Anish Jacob Cherian, Deepak T Abraham, MJ Paul
Journal: Journal of Clinical Oncology (2012)

e19562 Background: Phyllodes tumor of the breast (PT) has local recurrences resulting in higher morbidity and disfiguring reoperations. Aim to find factors predicting local recurrences in PT. Methods: Retrospective data analyzed with SPSS v.17 (Pearson Chi square test, Logistic regression test for multivariate analysis) done on patients with PT managed during 2000-2010. Results: In total 141 patients with PT, mean age was 40.44 years (+0.98) and mean tumor size 11.07 cm (+0.57). Preoperatively cytology done in 96 % and was suggestive of PT in 59%; core biopsy done in 58 % and was suggestive of PT in 93% Imaging done in 65%. The mean duration of lump- 2.2 years (+0.23). Thirty two patients (23%) presented with recurrence post lumpectomy done elsewhere. Adjuvant radiotherapy was given in 28% patients. In multivariate analysis, high stromal cellularity ( p 0.002), surgery type (p= 0.000) and recurrent status (p=0.05) at first time presentation showed statistically significant p values for odd’s ratios. Conclusions: Tumor size, margins, surgery type, histological features of high stromal hypercellularity, necrosis with high mitotic rates predicted recurrence in PT. Core biopsy is more accurate than fine needle biopsy in diagnosis and recommended in suspected cases to permit the correct initial surgery. [Table: see text]
Confirmation of double-peaked time distribution of mortality for breast cancer in a population-based study
Authors: N. S. Wong, F. Gao, S. B. Tan, D. Machin, E. H. Ng
Journal: Journal of Clinical Oncology (2006)

593 Background: Double-peaked time distributions of mortality hazard function have been reported for breast cancer patients from Western populations treated with mastectomy alone and is thought to reflect accelerated tumor growth at metastatic sites mediated by angiogenesis after primary tumor removal. Similar data is not available for Asian populations. We sought to investigate if differences exist in the pattern of mortality hazard function between Western breast cancer patients and Asian patients in Singapore treated with mastectomy alone which may suggest underlying differences in tumor biology between the two populations. Methods: We performed a retrospective cohort study of 3809 female unilateral breast cancer patients registered in the Singapore Breast Cancer Registry between October 1994 to June 1999. Data regarding patient demographics, tumor characteristics and death data were available. Overall survival curves were calculated using the Kaplan-Meier method and compared by the log-rank test. Death-specific hazard rate was calculated as the conditional probability of dying in a time interval, given that the patient was alive at the beginning of the interval. The life table method was used to calculate the yearly hazard rates. All tests were two-sided and significant at the 5% level. Results: In this cohort, 1169 patients (45.9%) had mastectomy alone without further adjuvant therapy. Demographics were: median age 55; 87.4% Chinese; 62.9% postmenopausal; 51.6% hormone receptor positive; 70.3% node negative; 22.8% high histological grade; 76.9% stage I or II. A double-peaked mortality hazard pattern, with a first major mortality rise reaching the maximum at the 2 nd - 4 th year after diagnosis and a second small mortality rise near the 9 th year was observed. Analyses by subgroups showed a similar pattern in node positive or high grade tumors but not in node negative or well to moderately differentiated tumors. A double peaked pattern was seen regardless of menopausal status. The double-peaked pattern observed in our patients was quantitatively and qualitatively similar to that reported by Western series. Conclusions: Our study confirms a double-peaked process in Asian patients and gives further support to the tumor dormancy hypothesis. No significant financial relationships to disclose.
The changing epidemiology of diphtheria in the United Kingdom, 2009 to 2017
Authors: Charlotte M Gower, Antonia Scobie, Norman K Fry, David J Litt, J Claire Cameron, Meera A Chand, Colin S Brown, Sarah Collins, Joanne M White, Mary E Ramsay, Gayatri Amirthalingam
Journal: Eurosurveillance (2020)

Background Diphtheria is a potentially fatal disease caused by toxigenic strains of Corynebacterium diphtheriae, C. ulcerans or C. pseudotuberculosis. Aim Our objective was to review the epidemiology of diphtheria in the United Kingdom (UK) and the impact of recent changes in public health management and surveillance. Methods Putative human toxigenic diphtheria isolates in the UK are sent for species confirmation and toxigenicity testing to the National Reference Laboratory. Clinical, epidemiological and microbiological information for toxigenic cases between 2009 and 2017 are described in this population-based prospective surveillance study. Results There were 33 toxigenic cases of diphtheria aged 4 to 82 years. Causative species were C. diphtheriae (n = 18) and C. ulcerans (n = 15). Most C. diphtheriae cases were cutaneous (14/18) while more than half of C. ulcerans cases had respiratory presentations (8/15). Two thirds (23/33) of cases were inadequately immunised. Two cases with C. ulcerans infections died, both inadequately immunised. The major risk factor for C. diphtheriae aquisition was travel to an endemic area and for C. ulcerans, contact with a companion animal. Most confirmed C. diphtheriae or C. ulcerans isolates (441/507; 87%) submitted for toxigenicity testing were non-toxigenic , however, toxin positivity rates were higher (15/23) for C. ulcerans than C. diphtheriae (18/469). Ten non-toxigenic toxin gene-bearing (NTTB) C. diphtheriae were also detected. Conclusion Diphtheria is a rare disease in the UK. In the last decade, milder cutaneous C. diphtheriae cases have become more frequent. Incomplete vaccination status was strongly associated with the risk of hospitalisation and death.
Gastric Gastrointestinal Stromal Tumor Incidentally Detected With Meckel Scintigraphy
Authors: Susan M. Hamman, Deepa R. Biyyam, Gerald A. Mandell
Journal: Clinical Nuclear Medicine (2020)

A 17-year-old boy presented with fatigue, hypoxia, palpitations, and anemia (hemoglobin 3.5 g/dL). The search for the etiology of the bleeding began with a Meckel scan. A photopenic region in the gastric body and a region of abnormal tracer uptake in the right midabdomen were unexpected findings. Further investigation with ultrasound and computed tomography revealed a gastric mass, which proved to be a gastrointestinal stromal tumor at pathology. The right-sided tracer uptake resulted from stasis in the collecting system of a malpositioned right kidney, a cause of false uptake in a Meckel scan.
ALARMINGLY RISING TRENDS IN VENOUS THROMBOEMBOLIC EVENTS AND RESPIRATORY FAILURE IN TAKOTSUBO SYNDROME-RELATED HOSPITALIZATIONS IN THE UNITED STATES
Authors: Rushikkumar R. Bhuva, Rupak Desai, Ahmed Mahmood, Sonali Sachdeva, Fariah Asha Haque, Nanush Damarlapally, Kishorbhai Gangani, Zarna Bambhroliya, Rajesh Sachdeva, Gautam Kumar
Journal: Journal of the American College of Cardiology (2020)