THU0480 IS PROLONGED SEDENTARY TIMEASSOCIATED WITH THE IMPACT OF THE DISEASE IN WOMEN WITH FIBROMYALGIA? THE AL-ÁNDALUS PROJECT
Authors: Víctor Segura-Jiménez, Blanca Gavilán Carrera, Pedro Acosta-Manzano, Alberto Soriano Maldonado, Inmaculada C Alvarez-Gallardo, Fernando Estevez-Lopez
Journal: Annals of the Rheumatic Diseases (2019)

<h3>Background</h3> Spending time seated has previously shown to be associated with worse symptomatology in fibromyalgia<sup>1</sup>. In addition, to accumulate sedentary time (ST) in prolonged, unbroken periods (bouts) has shown to be particularly harmful in the general population<sup>2</sup>. <h3>Objectives</h3> To examine the association of prolonged ST with the impact of the disease in women with fibromyalgia. <h3>Methods</h3> Four-hundred-and-seven (51.4±7.6 years old) fibromyalgia women participated in this cross-sectional study. Sedentary time accumulated in bouts of ≥10, ≥20, ≥30 and ≥60 minutes, and moderate-to-vigorous physical activity (MVPA) were measured with triaxial accelerometry (GT3X+). To control for total ST, the percentage of ST spent in different bout categories were calculated (e.g., (time spent in bouts ≥30 min/ total ST) ×100). We assessed different domains of fibromyalgia impact (function, overall, symptoms) and the global impact of fibromyalgia (total score) with the Revised Fibromyalgia Impact Questionnaire (FIQR). Separate linear regression models were built to assess the association of percentage of ST spent in different bout categories (independent variables) with the domains of fibromyalgia impact and the global impact of the disease (dependent variable) while controlling for age, fat percentage, medication for pain and depression, and total accelerometer wear time. Model 2 additionally included time spent in MVPA. <h3>Results</h3> Greater percentage of ST spent in bouts ≥10 min (β=0.171, p&lt;0.001), ≥20 min (β=0.163, p=0.001), ≥30 min (β=0.169, p&lt;0.001), and ≥60 min (β=0.161, p=0.001) was associated with greater global impact of the disease. In model 2, greater percentage of ST spent in bouts ≥10 min (β=0.145, p=0.003), ≥20 min (β=0.138, p&lt;0.004), ≥30 min (β=0.146, p&lt;0.002), and ≥60 min (β=0.144, p&lt;0.002) was associated with greater global impact of the disease. Similar results were observed for the association of percentage of sedentary time spent in different bout categories with the domains of fibromyalgia impact (function, overall, and symptoms). <h3>Conclusion</h3> The results seem to indicate that ST accumulated in bouts is negatively associated with the impact of the disease in women with fibromyalgia. Overall, these associations were independent of time spent in MVPA. It might be advisable to promote reducing prolonged ST in this population. <h3>References</h3> [1] Segura-Jiménez V, Borges-Cosic M, Soriano-Maldonado A, et al. Scand. J. Med. Sci. Sports. 2017;27:83–92. [2] Benatti FB, Ried-Larsen M. Med. Sci. Sports Exerc. 2015;47:2053–61. <h3>Acknowledgement</h3> We thank all the study participants for their collaboration. Funding: This study was supported by the Spanish Ministry of Economy and Competitiveness (I+D+i DEP2010-15639; I+D+I DEP2013-40908-R; BES-2014-067612) and the Spanish Ministry of Education (FPU 15/00002) <h3>Disclosure of Interests</h3> None declared