tbuckley/cabot-search huggingface dataset:
Combination of Ofatumumab and Lenalidomide In Patients with Relapsed Chronic Lymphocytic Leukemia: Initial Results of a Phase II Trial
Authors: Xavier Badoux, Susan O'Brien, William G. Wierda, Stefan Faderl, Zeev Estrov, Kimberly Yerrow, Hagop M. Kantarjian, Michael J Keating, Alessandra Ferrajoli
Journal: Blood (2010)
Aberrant Expression Of miRNA and mRNA Of Cell Cycle and Adhesion-Related Genes In Bone Marrow Stroma Cells Derived From Patients With Multiple Myeloma
Authors: Rimma Berenstein, Blau Igor Wolfgang, Axel Nogai, Marlies Wächter, Antonio Pezzutto, Bernd Dörken, Olga Blau
Journal: Blood (2013)
Comparison of the Safety Profile of Sickle Cell Disease Patients Treated with Hydroxycarbamide in Off-Label Versus in-Label Prescriptions in the Escort-HU Non Interventional, Prospective, Observational Open-Label Cohort Study
Authors: Ersi Voskaridou, Stephan Lobitz, Uwe Kordes, Regine Grosse, Valentine Brousse, Malika Benkerrou, Mariane De Montalembert, Jean-Antoine Ribeil, Frederic Galacteros
Journal: Blood (2016)
Characterization of optimal T Cell/Dendritic Cell (DC) Co-Culture Conditions for Ex Vivo Expansion of Antigen-Specific Human T Cells.
Authors: Krishna V. Komanduri, Michael Thomas, Lisa S. St. John, Dongxia Xing, William Decker, Simon Robinson, Hong Yang, Jeffrey J. Molldrem, Richard E. Champlin, John D. McMannis, Elizabeth J. Shpall
Journal: Blood (2006)
Murine and Human NF1 Haploinsufficient Mast Cells Promote Alterations in Fibroblast Function and Organization of the Extracellular Matrix in Three-Dimensional Collagen Lattices and this Gain in Function Is Abrogated by the Addition of STI-571.
Authors: Fengchun Yang, Clegg Travis, Shi Chen, Xiaohong Li, Selina A. Estwick, Jin Yuan, David A. Ingram, D. Wade Clapp
Journal: Blood (2004)
Oncogenic NK-Like Homeodomain Proteins Inhibit Etoposide-Induced Apoptosis in T-ALL Cell Lines by Activation of the Polycistronic miR-17-92 Transcript.
Authors: Stefan Nagel, Letizia Venturini, Corinna Meyer, Hans G. Drexler, Roderick A.F. MacLeod, Michaela Scherr
Journal: Blood (2007)
Generation of Ips Cell-Derived Hematopoietic Progenitor Cells from Patients with Acquired Aplastic Anemia Harboring Copy Number Neutral Loss of Heterozygosity of the Short Arm of Chromosome 6
Authors: Luis Espinoza, Yoshinori Yoshida, Kazuhisa Chonabayashi, Takamasa Katagiri, Yoshitaka Zaimoku, Shinji Nakao
Journal: Blood (2015)
Circulating Mir-16 and Mir-25 As New Prognosticators For Multiple Myeloma
Authors: Flavia Pichiorri, Alberto Rocci, Craig C Hofmeister, Susan Geyer, Tiffany Talabere, Massimiliano Gambella, Luciano Cascione, Andrew Stiff, Don M. Benson, Yvonne A Efebera, Vijaya Dirisala, Emily M Smith, Paola Omedè, Pellegrino Musto, Davide Rossi, Silvia Gentili, Giuseppina Uccello, Roberto Ria, Giulia Benevolo, Sara Bringhen, Vincenzo Callea, Brendan M Weiss, Alfredo Ferro, Valeria Magarotto, Hansjuerg Alder, John C. Byrd, Mario Boccadoro, Guido Marcucci, Antonio Palumbo
Journal: Blood (2013)
The CXCR4 Inhibitor Plerixafor Effectively Mobilizes Primary AML in NODscid IL2Rγc−/− Xenografts and Markedly Reduces but Does Not Eradicate Leukemia in Combination with Cytarabine +/− Clofarabine Chemotherapy
Authors: Sylvia Chien, Xin Zhao, Thalia Papayannopoulou, Frederick R. Appelbaum, Pamela S. Becker
Journal: Blood (2011)
Postranslationally Modified Proteins in the Central Nervous System (CNS) Are the Dominant Antigenic Target/Stimulus of the B-Cell Receptor (BCR) in Primary CNS Lymphomas (PCNSL) Providing Strong Evidence for the Role of Chronic Autoantigenic Stimulation As an Early Step in the Pathogenesis of Aggressive B-Cell Lymphomas
Authors: Lorenz Thurner, Maria Kemele, Natalie Fadle, Evi Regitz, Patrick Roth, Michael Weller, Monika Szczepanowski, Wolfram Klapper, Camelia-Maria Monoranu, Andreas Rosenwald, Rolf Buslei, Rainer Maria Bohle, Yoo-Jin Kim, Klaus-Dieter Preuss, Michael Pfreundschuh
Journal: Blood (2014)
Preferentially Expressed Antigen of Melanoma (PRAME)-Specific Cytotoxic T-Lymphocytes (CTLs) and Transgenic T Cells To Target Chronic Myelogenous Leukemia (CML).
Authors: C. Quintarelli, G. Dotti, B. De Angelis, V. Hoyos, M. Mims, F. Pane, Helen E. Heslop, C.M. Rooney, M.K. Brenner, B. Savoldo
Journal: Blood (2007)
Genome Wide Association Study of Sickle Cell Disease Individuals with Stroke Risk
Authors: Rayra Pereira Santiago, Camilo Vieira, Corynne Stephanie Ahouefa Adanho, Caroline Conceição Guarda, Sanzio Silva Santana, Camylla Vilas Boas Figueiredo, Milena Magalhães Aleluia, Thassila Nogueira Pitanga, Luciana Magalhaes Fiuza, Vitor Valério Maffili, Júnia Raquel Dutra Ferreira, Rodrigo Mota Oliveira, Isa Menezes Lyra, Dalila Luciola Zanette, Marilda Souza Goncalves
Journal: Blood (2016)
Clofarabine in Combination with High-Dose Cytarabine and Liposomal Daunorubicin in Pediatric AML: Results of a Phase 1B Combination Study By the ITCC Consortium
Authors: Christian M. Zwaan, Michael Dworzak, Thomas Klingebiel, Claudia Rössig, Guy Leverger, Jan Stary, Evelina S. de Bont, Satianand Ramnarain, Yves Bertrand, Benoit Brethon, Brigitte Strahm, Gertjan J. Kaspers, Dirk Reinhardt
Journal: Blood (2014)
Favorable Outcome of Patients with Relapsed Hodgkin Lymphoma (HL) after Nonmyeloablative Hematopoietic Cell Transplantation (NM-HCT) Using Related Haploidentical Donors.
Authors: Paul O’Donnell, Leo Luznik, Heather Symons, Richard Jones, Ted Gooley, Elizabeth Harrington, Sandra Warnock, Brenda Sandmaier, Rainer Storb, Ephraim Fuchs
Journal: Blood (2006)
Correlation of Clinical Features with Mutational Status in Children with Juvenile Myelomonocytic Leukemia.
Authors: Nao Yoshida, Hiroshi Yagasaki, Yinyan Xu, Makito Tanaka, Nobuhiro Nishio, Hirokazu Hidaka, Asahito Hama, Yoshiyuki Takahashi, Atsushi Manabe, Seiji Kojima
Journal: Blood (2006)
Umbilical Cord Blood-Derived Stem Cells Cultured Under Low Oxygen Tension Enhance the Migration and Homing Efficiency through the Increased Expression of CXCR4.
Authors: Norioki Ohno, Teruyuki Kajiume, Seiichi Hayakawa, Yoshiyuki Kobayashi, Akari Utunomiya, Masao Kobayashi
Journal: Blood (2010)
ROR1 Specific T Cell Clones from Healthy Individuals Show Common T Cell Receptor Motifs
Authors: Falk Heidenreich, Elke Ruecker-Braun, Juliane S. Stickel, Anne Eugster, Denise Kühn, Sevina Dietz, Annika Nelde, Antje Tunger, Rebekka Wehner, Jan Moritz Middeke, Cornelia S Link, Friedrich Stölzel, Stefan Stevanovic, Ezio Bonifacio, Martin Bornhäuser, Gerhard Ehninger, Marc Schmitz, Johannes Schetelig
Journal: Blood (2016)
Influence of Age on Risk for Acute and Chronic Graft Versus Host Disease in Children Receiving HLA Identical Sibling Bone Marrow Transplantation
Authors: Muna Qayed, John Horan, Stephen R. Spellman, Mukta Arora, Tao Wang, Michael Hemmer, Joseph A Pidala, Daniel Couriel, Amin M. Alousi
Journal: Blood (2016)
Limits of Phenotype Analyses in the Diagnosis of HbS Heterozygosity. Example of a Hb S Carrier Phenocopy Due to Hb Arya (Alpha 1: codon 47 Asp&gt;Asn) and a Gene Conversion
Authors: Serge Pissard, Adrien Pecriaux, Catherine Paillard, Anne Galoisy, Jean Riou, Nathalie Le Metayer, Henri Wajcman
Journal: Blood (2016)
Follicular Lymphoma-Like B Cells In Healthy Individuals Are Released From Pretumoral Niches Established In Secondary Lymphoid Tissues
Authors: Sandrine Roulland, Stephanie Sungalee, Emilie Gregoire, Fabien Guilloton, Ester Morgado, Emilie Mamessier, Cedric Menard, Celine Monvoisin, Jean Hardwigsen, Claudine Schiff, Karin Tarte, Bertrand Nadel
Journal: Blood (2010)
Increased Disease Progression in HLA-a, -B, -C, -DRB1 and -DBP1 Matched Recipients of Unrelated Donor Transplants with Peripheral Blood Is Independent of Risk Groups By Disease Risk Index
Authors: Betul Oran, Rima M Saliba, Yudith Carmazzi, Elizabeth J. Shpall, Katayoun Rezvani, Marcos De Lima, Marcelo Fernández-Viña, Richard E. Champlin, Kai Cao
Journal: Blood (2015)
Inhibition of Chronic Myelogenous Leukemia Stem Cells with Novel Wnt Antagonists.
Authors: Edward Kavalerchik, Jason Gotlib, Ifat Geron, Annelie Abrahamsson, Wolfgang Wrasidlo, Daniel Goff, Desheng Lu, Ted Molinski, Francis Giles, Irving Weissman, Dennis Carson, Catriona Jamieson
Journal: Blood (2006)
Incidence Of Atypical Chronic Lymphocytic Leukemia In 1819 Patients With B Chronic Lymphoproliferative Disorder
Authors: Edouard Cornet, Alice-Sophie Boucher, Véronique Salaun, Florence Truquet, Michele Malet, Dina Naguib, Françoise Galateau-Salle, Xavier Troussard
Journal: Blood (2013)
Treatment of Acute Graft-Versus-Host Disease by Means of Multipotent Mesenchymal Stromal Cells: Role of Immunomodulating Soluble Factors Expressed by These Cells in Vitro
Authors: Natalia A. Petinaty, Larisa A. Kuzmina, Irina N. Shipounova, Oxana A Zhironkina, Alexey Bigildeev, Lidya S. Lubimova, Elena O. Gribanova, Elena N Parovichnikova, Nina I. Drize, Valeri G Savchenko
Journal: Blood (2011)
Escalated lymphodepletion Followed by Donor Lymphocyte Infusion (DLI) can Induce a Graft-Versus-Host Response without Overwhelming Toxicity.
Authors: Thierry Guillaume, Patrice Chevallier, Sameh Ayari, Jacques Delaunay, Francoise Mechinaud, Philippe Moreau, Mohamad Mohty
Journal: Blood (2009)
Functional Analysis of a Peptide Sequence (Thr323 - Cys337) In ADAMTS13 Disintegrin-Like Domain Revealed Two Discontinuous Sequences Involved In the Interaction with VWF
Authors: Atsuko Igari, Takanori Moriki, Terumichi Nakagawa, Yusuke Yamaguchi, Mitsuru Murata
Journal: Blood (2010)
No Evidence of Cis-Acting SNPs In Immune Response Genes Previously Associated with Factor VIII Inhibitors: The San Antonio Family Heart Study
Authors: Tom E. Howard, Kevin R. Viel, Eugene Drigalenko, Shelley Cole, Melinda Epstein, Melanie Carless, Richard Hughes, Benjamin Kim, Tom Dyer, Kathleen P. Pratt, Jean W. MacCluer, Joanne E. Curran, Matthew P. Johnson, Eric K. Moses, John Blangero, Laura Almasy, Harald Göring
Journal: Blood (2010)
Very Good Partial Response and Complete Response Predict Superior Overall Survival and Progression Free Survival After Single Autologous Stem Cell Transplant in Patients with Multiple Myeloma,
Authors: Victor H Jimenez-Zepeda, Donna E. Reece, Suzanne Trudel, Christine Chen, Andrew Winter, Norman Franke, Rodger E. Tiedemann, Vishal Kukreti
Journal: Blood (2011)
TNFRSF14 Is Mutated in a Subset of Follicular Lymphoma and Correlated with Inferior Prognosis.
Authors: K-John Cheung, Nathalie Johnson, Joslynn Affleck, Tesa Severson, Christian Steidl, Susanna Ben-Neriah, Jacqueline Schein, Ryan Morin, Richard Moore, Sohrab P Shah, Hong Qian, Jessica Paul, Adele Telenius, Betty Lai, Thomas Relander, Wan L Lam, Kerry J. Savage, Joseph M Connors, Carolyn Brown, Marco Marra, Randy D. Gascoyne, Douglas E. Horsman
Journal: Blood (2009)
Long-Term Follow-up of Autologous Hematopoietic Stem Cell Transplantation (AHSCT) for Acute Myeloid Leukemia (AML): A Survey of 3567 Patients From the Acute Leukemia Working Party of the EBMT.
Authors: Tomasz Czerw, Myriam Labopin, Norbert C. Gorin, Sebastian Giebel, Didier Blaise, Giovanna Meloni, Arnaud Pigneux, Alberto Bosi, Hendrik Veelken, Felicetto Ferrara, Nicolaas Schaap, Michele Baccarani, Mohamad Mohty
Journal: Blood (2012)
the Polymorphisms on Chromosome 9p21 Play a Role in the Risk for Cardiovascular Events in Chronic Myeloid Leukemia Patients?
Authors: Federica Sora, Patrizia Chiusolo, Laurenti Luca, Pola Roberto, Sabrina Giammarco, Gatto Ilaria, Andrea Bacigalupo, Simona Sica, Abruzzese Elisabetta, Celesti Francesca
Journal: Blood (2016)
A Phase 1 Study Evaluating Pharmacokinetics (PK) and Safety of Carfilzomib in Patients with Advanced Malignancies and Varying Degrees of Hepatic Impairment (HI)
Authors: Jennifer Brown, Ruth Plummer, Stephen Anthony, John Sarantopoulos, Filip De Vos, Mike White, Marco Schupp, Ying Ou, Ulka Vaishampayan
Journal: Blood (2016)
Essential Thrombocythemia (ET) and Polycythemia Vera (PV) Symptom Burden: Phenotypic Cluster Analysis Among an International Sample of 1,141 ET and PV Patients
Authors: Robyn M. Emanuel, Amylou C. Dueck, Holly Lynn Geyer, Jean-Jacques Kiladjian, Stefanie Slot, Sonja Zweegman, Peter te Boekhorst, Suzan Commandeur, Harry C Schouten, Federico Sackmann, Ana Kerguelen Fuentes, Dolores Hernandez, Heike L. Pahl, Martin Griesshammer, Frank Stegelmann, Konstanze Doehner, Thomas Lehmann, Karin Bonatz, Andreas Reiter, Françoise Boyer, Gabriel Etienne, Jean-Christophe Ianotto, Dana Ranta, Lydia Roy, Jean-Yves Cahn, Claire N Harrison, Deepti H Radia, Pablo J. Muxi, Norman I Maldonado, Carlos Besses, Francisco Cervantes, Peter Johansson, Tiziano Barbui, Giovanni Barosi, Alessandro M. Vannucchi, Francesco Passamonti, Bjorn Andreasson, Maria L Ferarri, Alessandro Rambaldi, Gunnar Birgegard, Zhijian Xiao, Zefeng Xu, Yue Zhang, Xiujuan Sun, Junqing Xu, Peihong Zhang, Robert Peter Gale, Ayalew Tefferi, Ruben A. Mesa
Journal: Blood (2012)
Natural Killer Cells Contribute to Pathophysiology of Placenta Leading to Miscarriage in Fetal and Neonatal Alloimmune Thrombocytopenia
Authors: Issaka Yougbare, Tai Wei-she, Darko Zdravic, Pingguo Chen, Guangheng Zhu, Howard Leong-Poi, Qu Dawei, X. Lisa Yu, S. Adamson Lee, John Sled, Freedman John, Heyu Ni
Journal: Blood (2015)
PU.1 Relieves Its GATA-1-Mediated Repression near Cebpa and Cbfb During Transdifferentiation of Murine Erythroleukemia - Tool of Inducing Leukemic Blasts to Differentiate.
Authors: Pavel Burda, Nikola Curik, Juraj Kokavec, Dana Mikulenkova, Arthur Skoultchi, Jiri Zavadil, Tomas Stopka
Journal: Blood (2009)
Constitutive Phosphoinositide-3kinase Activation Represents a Good Prognostic Factor in De Novo AML Patients under 60 Years.
Authors: Jerome Tamburini, Caroline Elie, Valerie Bardet, Sophie Park, Philippe Broet, Pascale Cornillet Lefebvre, Bruno Lioure, Norbert Ifrah, Francis Witz, Jean Luc Harousseau, Francois Dreyfus, Patrick Mayeux, Catherine Lacombe, Didier Bouscary
Journal: Blood (2006)
High Level of CD71 Expression On Neoplastic B Cells At Diagnosis Is Predictive of Overall Survival After Rituximab and Anthracyclines Based Regimen in Follicular Lymphoma
Authors: FS de Fontbrune, Danielle Canioni, Hugo Chapdelaine, Richard Delarue, Nicole Brousse, Felipe Suarez, Olivier Hermine
Journal: Blood (2012)
Ofatumumab (OFA) Maintenance Prolongs PFS in Relapsed CLL: Prolong Study Interim Analysis Results
Authors: Marinus H.J. van Oers, Kazimierz Kuliczkowski, Lukas Smolej, Mario Petrini, Fritz Offner, Sebastian Gorsicki, Mark-David Levin, Ira Gupta, Jennifer Phillips, Vanessa Williams, Steen Lisby, Christian Geisler
Journal: Blood (2014)
Prophylactic Dosing of Anti-Inhibitor Coagulant Complex (FEIBA) Reduces Bleeding Frequency In Hemophilia A Patients with Inhibitors: Results of the Pro-FEIBA Study
Authors: Cindy A. Leissinger, Eric Berntorp, Chiara Biasioli, Shannon Carpenter, Hyejin Jo, Kaan Kavakli, Claude Negrier, Angiola Rocino, Jerzy Windyga, Bulent Zulfikar, Alessandro Gringeri
Journal: Blood (2010)
Trends in High- and Low-Value Cardiovascular Diagnostic Testing in Fee-for-Service Medicare, 2000-2016
Authors: Vinay Kini, Timea Viragh, David Magid, Frederick A. Masoudi, Ali Moghtaderi, Bernard Black
Journal: JAMA Network Open (2019)

<h3>Importance</h3> Owing to a rapid increase in rates of diagnostic cardiovascular testing in the 1990s and early 2000s, the Centers for Medicare &amp; Medicaid Services implemented a series of payment changes intended to reduce overall spending on fee-for-service testing. Whether guideline-concordant testing has been subsequently affected is unknown to date. <h3>Objective</h3> To determine whether changes in overall rates of use of diagnostic cardiovascular tests were associated with changes in high-value testing recommended by guidelines and low-value testing that is expected to provide minimal benefits. <h3>Design, Setting, and Participants</h3> This retrospective cohort study assessed a national 5% random sample of Medicare fee-for-service beneficiaries aged 65 to 95 years from January 1, 1999, through December 31, 2016. Data were analyzed from February 15, 2018, through August 15, 2019. <h3>Exposures</h3> Eligibility to receive high-value testing (assessment of left ventricular systolic function among patients hospitalized with acute myocardial infarction or heart failure) and low-value testing (stress testing before low-risk noncardiac surgery and routine stress testing within 2 years of coronary revascularization not associated with acute care visits). <h3>Main Outcomes and Measures</h3> Age- and sex-adjusted annual rates of overall, high-value, and low-value diagnostic cardiovascular testing. <h3>Results</h3> Mean (SD) age was similar over time (75.57 [7.32] years in 2000-2003; 74.82 [7.79] years in 2012-2016); the proportion of women slightly declined over time (63.23% in 2000 to 2003; 57.27% in 2012 to 2016). The rate of overall diagnostic cardiovascular testing per 1000 patient-years among the 5% sample of Medicare beneficiaries increased from 275 in 2000 to 359 in 2008 (<i>P</i> &lt; .001) and then declined to 316 in 2016 (<i>P</i> &lt; .001). High-value testing increased steadily over the entire study period for patients with acute myocardial infarction (85.7% to 89.5%;<i>P</i> &lt; .001) and heart failure (72.6% to 80.1%;<i>P</i> &lt; .001). Low-value testing among patients undergoing low-risk surgery increased from 2.4% in 2000 to 3.8% in 2008 (<i>P</i> &lt; .001) but then declined to 2.5% in 2016 (<i>P</i> &lt; .001). Low-value testing within 2 years of coronary revascularization slightly increased from 47.4% in 2000 to 49.2% in 2003 (<i>P</i> = .03) but then declined to 30.8% in 2014 (<i>P</i> &lt; .001). <h3>Conclusions and Relevance</h3> Rates of overall and low-value diagnostic cardiovascular testing appear to have declined considerably and rates of high-value testing have increased slightly. Payment changes intended to reduce spending on overall testing may not have adversely affected testing recommended by guidelines.
Alterations In the Signaling Profile of Leukemic Progenitors Can Predict the Response of Myelodysplastic Syndrome (MDS) Patients to Azacytidine
Authors: Paraskevi Miltiades, Irene Bouchliou, Evangelia Nakou, Emmanuil Spanoudakis, Sotirios Papageorgiou, Vasiliki Pappa, Maria Papaioannou, Eleytherios Moustakidis, Sofia Vakalopoulou, Vasilia Garipidou, Konstantinos Tsatalas, Ioannis Kotsianidis
Journal: Blood (2010)
Bcl10 is required for the development and suppressive function of Foxp3+ regulatory T cells
Authors: Dandan Yang, Xueqiang Zhao, Xin Lin
Journal: Cellular and Molecular Immunology (2019)

Foxp3+ regulatory T (Treg) cells play a critical role in peripheral tolerance. Bcl10, acting as a scaffolding protein in the Carma1-Bcl10-Malt1 (CBM) complex, has a critical role in TCR-induced signaling, leading to NF-κB activation and is required for T-cell activation. The role of Bcl10 in conventional T (Tconv) cells has been well characterized; however, the role of Bcl10 in the development of Treg cells and the maintenance of the suppressive function and identity of these cells has not been well characterized. In this study, we found that Bcl10 was required for not only the development but also the function of Treg cells. After deleting Bcl10 in T cells, we found that the development of Treg cells was significantly impaired. When Bcl10 was specifically deleted in mature Treg cells, the suppressive function of the Treg cells was impaired, leading to lethal autoimmunity in Bcl10fl/flFoxp3cre mice. Consistently, in contrast to WT Treg cells, Bcl10-deficient Treg cells could not protect Rag1-deficient mice from T-cell transfer-induced colitis. Furthermore, Bcl10-deficient Treg cells downregulated the expression of a series of Treg-cell effector and suppressive genes and decreased effector Treg-cell populations. Moreover, Bcl10-deficient Treg cells were converted into IFNγ-producing proinflammatory cells with increased expression of the transcription factors T-bet and HIF-1α. Together, our study results provide genetic evidence, indicating that Bcl10 is required for the development and function of Treg cells.
Landscape of TET2 Mutations In Acute Myeloid Leukemia (AML): A Next-Generation Sequencing Study Investigating 76 Cases Comprehensively Characterized for Cytogenetics and Other Molecular Markers.
Authors: Sandra Wille, Vera Grossmann, Tamara Alpermann, Claudia Haferlach, Wolfgang Kern, Susanne Schnittger, Torsten Haferlach, Alexander Kohlmann
Journal: Blood (2010)
Prevalence and Predictors of Pulmonary Arterial Hypertension in Hemoglobin E/ β-Thalassemia Patients.
Authors: Suporn Chuncharunee, Vichai Atichartakarn, Napaporn Archararit, Umaporn Udomsubpayakul, Atiporn Ingsathit, Ratchanee Lee, Anusith Tunhasiriwet, Supachai Tanomsup, Katcharin Aryurachai, Artit Ungkanont, Pimjai Niparuck, Pantep Angchaisuksiri
Journal: Blood (2009)
Final Results from an International, Multi-Center, Single-Arm Study Evaluating the Safety and Efficacy of Romiplostim in Adults with Primary Immune Thrombocytopenia (ITP),
Authors: Ann Janssens, Michael D. Tarantino, Robert Bird, Maria Gabriella Mazzucconi, Ralph Vincent V. Boccia, Maria Fernanda Lopez-Fernandez, Tomas Kozak, Michael Steurer, Peter A.W. Te Boekhorst, Kerry Dillingham, Richard Lizambri
Journal: Blood (2011)
GPs talked to fewer patients about alcohol after incentive scheme ended, study finds
Authors: Elisabeth Mahase
Journal: BMJ (2019)

GPs gave fewer patients advice on alcohol after practices stopped being paid through an alcohol directed enhanced service (DES) scheme and were expected to do the work through their normal contract, researchers have said.1

The researchers, from the Universities of Newcastle and Sheffield and University College London, compared how many patients were screened for alcohol use and given advice on consumption before the alcohol DES was introduced (2006-08), during (2008-15), and after it was withdrawn (2015-16).

They found that after the DES was withdrawn, the percentage of patients recorded as receiving advice immediately dropped and continued to do so until the study end.

But there were a number of other factors which could have influenced the findings, including changes to government policy and clinical guidance.

The alcohol DES was introduced in 2008 …
MLN0128 (INK128), an Investigational Oral Dual TORC1/2 Inhibitor, in Patients (pts) with Relapsed or Refractory Multiple Myeloma (MM), Non-Hodgkin's Lymphoma (NHL), or Waldenstrom Macroglobulinemia (WM): Preliminary Results From a Phase 1 Dose-Escalation Study
Authors: Irene M. Ghobrial, David Siegel, Ravi Vij, Jeffrey L Wolf, Jesus G. Berdeja, Jeffrey V. Matous, Peter Lipman, Chirag Patel, Trinh Le, Christian Rommel, Gregory Berk
Journal: Blood (2012)