Transplanting Hepatitis C Virus–Infected or Uninfected Kidneys Into Hepatitis C Virus–Infected Recipients
Authors: Bryce Kiberd, Karen Doucette, Amanda Vinson, Karthik Tennankore
Journal: Annals of Internal Medicine (2018)

Letters18 December 2018Transplanting Hepatitis C Virus–Infected or Uninfected Kidneys Into Hepatitis C Virus–Infected RecipientsBryce Kiberd, MD, Karen Doucette, MD, Amanda Vinson, BSc, SM, MD, and Karthik Tennankore, MDBryce Kiberd, MDDalhousie University, Halifax, Nova Scotia, Canada (B.K., K.T.)Search for more papers by this author, Karen Doucette, MDUniversity of Alberta, Edmonton, Alberta, Canada (K.D.)Search for more papers by this author, Amanda Vinson, BSc, SM, MDNova Scotia Health Authority, Halifax, Nova Scotia, Canada (A.V.)Search for more papers by this author, and Karthik Tennankore, MDDalhousie University, Halifax, Nova Scotia, Canada (B.K., K.T.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/L18-0565 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Eckman and colleagues (1) concluded that “transplanting [hepatitis C virus (HCV)]–infected kidneys into HCV-infected patients increased quality-adjusted life expectancy and reduced costs compared with transplanting HCV-uninfected kidneys into HCV-infected patients.” We have long advocated transplanting HCV-infected organs into HCV-infected recipients (2). Similar to Eckman and colleagues, we found that deferring treatment of HCV infection in recipients to allow them to receive an HCV-infected organ and subsequently be treated is more beneficial under some circumstances, which Goldberg and Reese (3) note in their editorial.However, the findings of our recent medical decision analysis (4) contrast with those of ...References1. Eckman MH, Woodle ES, Thakar CV, Paterno F, Sherman KE. Transplanting hepatitis C virus–infected versus uninfected kidneys into hepatitis C virus–infected recipients: a cost-effectiveness analysis. Ann Intern Med. 2018;169:214-23. [PMID: 29987322]. doi:10.7326/M17-3088 LinkGoogle Scholar2. Kiberd BA. Should hepatitis C-infected kidneys be transplanted in the United States? Transplantation. 1994;57:1068-72. [PMID: 8165705] CrossrefMedlineGoogle Scholar3. Goldberg DS, Reese PP. New insights into optimal timing of hepatitis C virus treatment for dialysis patients waitlisted for kidney transplant. Ann Intern Med. 2018;169:256-7. [PMID: 29987318]. doi:10.7326/M18-1718 LinkGoogle Scholar4. Kiberd BA, Doucette K, Vinson AJ, Tennankore KK. Hepatitis C virus-infected kidney waitlist patients: treat now or treat later? Am J Transplant. 2018;18:2443-50. [PMID: 29687948] doi:10.1111/ajt.14891 CrossrefMedlineGoogle Scholar5. Hart A, Smith JM, Skeans MA, Gustafson SK, Stewart DE, Cherikh WS, et al. OPTN/SRTR 2015 annual data report: kidney. Am J Transplant. 2017;17 Suppl 1:21-116. [PMID: 28052609] doi:10.1111/ajt.14124 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Dalhousie University, Halifax, Nova Scotia, Canada (B.K., K.T.)University of Alberta, Edmonton, Alberta, Canada (K.D.)Nova Scotia Health Authority, Halifax, Nova Scotia, Canada (A.V.)Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L18-0565. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoTransplanting Hepatitis C Virus–Infected Versus Uninfected Kidneys Into Hepatitis C Virus–Infected Recipients Mark H. Eckman , E. Steve Woodle , Charuhas V. Thakar , Flavio Paterno , and Kenneth E. Sherman Transplanting Hepatitis C Virus–Infected or Uninfected Kidneys Into Hepatitis C Virus–Infected Recipients Mark H. Eckman , E. Steve Woodle , Charuhas V. Thakar , Flavio Paterno , and Kenneth E. Sherman Metrics 18 December 2018Volume 169, Issue 12Page: 897-898KeywordsDecision analysisDecision makingDisclosureHepatitis CHepatitis C virusKidneysOpioidsQuality adjusted life expectancyRenal analysis ePublished: 18 December 2018 Issue Published: 18 December 2018 Copyright & PermissionsCopyright © 2018 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...