WEGENER'S GRANULOMATOSIS
Authors: G B GORDON, E GECHMAN, R ROSENGARTEN, A P NEPTUNE
Journal: Annals of Internal Medicine (1957)

Case Reports1 December 1957WEGENER'S GRANULOMATOSISGEORGE B. GORDON, M.D., ELIAS GECHMAN, M.D., ROBERT ROSENGARTEN, M.D., ANTHONY P. NEPTUNE, M.D.GEORGE B. GORDON, M.D.Search for more papers by this author, ELIAS GECHMAN, M.D.Search for more papers by this author, ROBERT ROSENGARTEN, M.D.Search for more papers by this author, ANTHONY P. NEPTUNE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-47-6-1260 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAmong the many clinicopathologic entities in which the fundamental lesion consists of widespread necrotizing angiitis and granuloma formation, Wegener's granulomatosis can be recognized as a distinctive syndrome. Its leading features are necrotizing granulomatous lesions of the nasal passages, sinuses and respiratory tract, generalized arteritis, and focal glomerulitis with terminal uremia. Klinger1 reported the first case in 1931, and Wegener2 described the features which distinguish this syndrome from other forms of angiitis. Extensive clinical3 and pathologic4 studies have formulated the criteria which make possible the clinical recognition of this rare disorder.The etiology of Wegener's granulomatosis is not known. Necrotizing angiitis,...Bibliography1. Klinger H: Grenzformen der Periarteritis nodosa, Frankfurt. Ztschr. f. Path. 42: 455-480, 1931. Google Scholar2. Wegener F: Über eine eigenartige rhinogene Granulomatose mit besonderer Beteiligung des Arteriensystems und der Nieren, Beitr. z. path. Anat. u. z. allg. Path. 102: 36-68, 1939. Google Scholar3. FaheyLeonardChurgGodman JEJG: Wegener's granulomatosis, Am. J. Med. 17: 168-179, 1954. CrossrefMedlineGoogle Scholar4. GodmanChurg GCJ: Wegener's granulomatosis, Arch. Path. 58: 533-553, 1954. MedlineGoogle Scholar5. OlinerTaubenhausShapiraLeshin LMTMN: Nonsyphilitic interstitial keratitis and bilateral deafness (Cogan's syndrome) associated with essential polyangiitis (periarteritis nodosa), New England J. Med. 248: 1001-1008, 1953. CrossrefMedlineGoogle Scholar6. ZeekSmithWeeter PMCCJC: Studies on periarteritis nodosa: differentiation between vascular lesions of periarteritis nodosa and of hypersensitivity, Am. J. Path. 24: 889-917, 1948. MedlineGoogle Scholar7. ChurgStrauss JL: Allergic granulomatosis, allergic angiitis, and periarteritis nodosa, Am. J. Path. 27: 277-301, 1951. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Brooklyn, N. Y.*Received for publication May 16, 1956.From the Departments of Medicine and Pathology, Beth-El Hospital, Brooklyn, N. Y.Requests for reprints should be addressed to George B. Gordon, M.D., 470 Ocean Avenue, Brooklyn 26, N. Y. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byWegenersche GranulomatoseThe concept of limited forms of Wegener's granulomatosisKlinik und Therapie der GlomerulonephritidenImmunologische Untersuchungen bei Wegenerscher Granulomatose mit Nachweis von ?-Globulin-Antik�rpernA patient with Wegener's granulomatosis exhibiting unusual clinical and morphologic featuresWEGENER'S GRANULOMATOSIS: A CASE REPORTThe auscultatory findings in primary myocardial diseaseDie Wegenersche GranulomatoseRHEUMATISM AND ARTHRITIS: REVIEW OF AMERICAN AND ENGLISH LITERATURE OF RECENT YEARS (THIRTEENTH RHEUMATISM REVIEW)*CHARLEY J. SMYTH, M.D., F.A.C.P., ROGER L. BLACK, M.D., FELIX E. DEMARTINI, M.D., IVAN F. DUFF, M.D., F.A.C.P., EPHRAIM P. ENGLEMAN, M.D., F.A.C.P., DONALD C. GRAHAM, M.D., F.R.C.P.(C), MAX M. MONTGOMERY, M.D., F.A.C.P., HOWARD F. POLLEY, M.D., F.A.C.P., EDWARD F. ROSENBERG, M.D., F.A.C.P., CARLOS F. SACASA, M.D., F.A.C.P., OTTO STEINBROCKER, M.D., HANS WAINE, M.D., GEORGE M. WILSON JR., M.D.XXXVIII Wegener's Granulomatosis 1 December 1957Volume 47, Issue 6Page: 1260-1266KeywordsAnemiaGlomerulonephritisGranulomasHospital medicineHypertensionLesionsRespiratory systemUreaVasculitisWegener granulomatosis ePublished: 1 December 2008 Issue Published: 1 December 1957 PDF downloadLoading ...