tbuckley/cabot-search huggingface dataset:
Abstract P5-02-06: High-risk lesions diagnosed at MRI-guided vacuum-assisted breast biopsy: Imaging characteristics, outcome of surgical excision or imaging follow-up
Authors: S Okamoto, JD Covelli, WB DeMartini, BL Daniel, DM Ikeda
Journal: Cancer Research (2019)

Abstract PURPOSE To evaluate imaging characteristics, outcome of surgical excision or imaging follow-up on high-risk lesions diagnosed at MRI-guided vacuum-assisted breast biopsy (MRI-VAB). MATERIALS AND METHODS We retrospectively reviewed 581 lesions, to include benign, high-risk and malignant lesions, undergoing 9-gauge MRI-VAB from January 2015 to April 2018. We collected patient demographics, risk factors and indications, breast MRI BI-RADS descriptors, histopathological diagnosis at MRI-VAB and surgical excision, frequency of upgrade to malignancy and imaging follow-up of high-risk lesions found in this period. RESULTS 101 patients with 107/581 (18.4% of all lesions) had high risk lesions at MRI-VAB, including atypical ductal hyperplasia (ADH)(n=19/107, 17.8%), lobular neoplasia (n=35/107, 32.7) including atypical lobular hyperplasia (ALH), lobular carcinoma in situ (LCIS), ALH plus LCIS, papillary lesions (n=44/107, 41.1%), radial scar/complex sclerosing lesion (RS/CSL)(n=8/107, 7.5%) and flat epithelial atypia (FEA)(n=1/107, 1%). 71/107 (66.4%) high risk lesions were excised. 16/71 (22.5%) were upgraded to malignancy (4 invasive cancer, 12 DCIS). The upgrade rate for ADH and lobular neoplasia was 5 /16 (31.3%) and 8/26 (30.8%) respectively. The upgrade rate for RS/CSL was 1/6 (16.7%). Of the 22 papillary lesions excised, 2 (9.1%) demonstrated pathologic atypia and were upgraded to DCIS. The other 20 papillary lesions had no upgrade or atypia. Excised high risk lesions showing upgrade varied from 0.4 to 6 cm in length (average 2.1 cm). Increasing size correlated with tendency towards increased upgrade to malignancy, but there were no other specific imaging features to predict malignancy upgrade. CONCLUSION There were no specific MRI imaging characteristics of high-risk lesions to predict malignancy upgrade. Therefore, surgical excision is recommended for high risk lesions especially ADH or lobular neoplasia. Additionally, non-atypical papillomas did not demonstrate malignancy upgrade in our small study. And further larger studies may demonstrate that these lesions may not need to be surgically excised. Citation Format: Okamoto S, Covelli JD, DeMartini WB, Daniel BL, Ikeda DM. High-risk lesions diagnosed at MRI-guided vacuum-assisted breast biopsy: Imaging characteristics, outcome of surgical excision or imaging follow-up [abstract]. In: Proceedings of the 2018 San Antonio Breast Cancer Symposium; 2018 Dec 4-8; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2019;79(4 Suppl):Abstract nr P5-02-06.
META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS COMPARING MECHANICALLY EXPANDABLE VERSUS SELF EXPANDABLE VALVES FOR PATIENTS UNDERGOING TRANSCATHETER AORTIC VALVE IMPLANTATION
Authors: Jai Parekh, Arun Kanmanthareddy, Abdulghani Saadi, Jitendra Pandya
Journal: Journal of the American College of Cardiology (2019)
Transcriptional Basis for Rhythmic Control of Hunger and Metabolism within the AgRP Neuron
Authors: Jonathan Cedernaes, Wenyu Huang, Kathryn Moynihan Ramsey, Nathan Waldeck, Lei Cheng, Biliana Marcheva, Chiaki Omura, Yumiko Kobayashi, Clara Bien Peek, Daniel C. Levine, Ravindra Dhir, Raj Awatramani, Christopher A. Bradfield, Xiaozhong A. Wang, Joseph S. Takahashi, Mohamad Mokadem, Rexford S. Ahima, Joseph Bass
Journal: Cell Metabolism (2019)
RIGHT BUNDLE BRANCH BLOCK INDUCED BY ALCOHOL SEPTAL ABLATION FOR HYPERTROPHIC OBSTRUCTIVE CARDIOMYOPATHY DOES NOT IMPACT BIVENTRICULAR REMODELING
Authors: Ahmadreza Karimianpour, Davis Leaphart, Mary Lark, Courtney Kramer, Christopher Nielsen, Valerian Fernandes, Michael Gold
Journal: Journal of the American College of Cardiology (2019)
FOCAL LEFT VENTRICULAR INTRAMYOCARDIAL FAT ON CT IN STABLE CHEST PAIN: INSIGHTS FROM PROMISE (PROSPECTIVE MULTICENTER IMAGING STUDY FOR EVALUATION OF CHEST PAIN)
Authors: Julia Karady, Thomas Mayrhofer, Borek Foldyna, Maros Ferencik, Michael Lu, Yasuka Kikuchi, Alexander Ivanov, Stefan B. Puchner, Hamed Emami, Nandini Meyersohn, Daniel Bittner, Pal Maurovich-Horvat, Pamela Douglas, Udo Hoffmann
Journal: Journal of the American College of Cardiology (2019)
Abstract 419: Deep Sequencing Provides Evidence Of Mitochondrial Abnormalities In Right Ventricular Failure In Pulmonary Arterial Hypertension
Authors: Francois Potus, Charles C Hindmarch, Stephen L Archer
Journal: Circulation Research (2018)

Introduction: Right ventricular (RV) function is a critical predictor of both morbidity and mortality in pulmonary arterial hypertension (PAH). In PAH patients present either with adaptive remodelling RV and compensatory RV hypertrophy (RVH), or maladaptive remodeling that rapidly deteriorates to RV failure (RVF). While the molecular mechanisms underlying RVF remain poorly understood, acquired mitochondrial abnormalities including impaired mitochondrial electron transport chain activity, altered metabolic substrate utilization, and aberrant mitochondrial dynamics likely play a crucial role. We assessed the role of mitochondria in RVF using an unbiased assessment of gene expression in the RV of rats with maladaptive vs adaptive RVH and PAH. Method and result: Male rats were treated with either sugen+hypoxia (SuHx) or Monocrotaline (MCT). We determined RV status using non-invasive echocardiography and right heart catheterisation. Compared to control (Ctrl; n=15) both MCT (n=8) and SuHx (n=5) rats displayed severe PAH with increased RVSP, mPAP, total pulmonary resistance (TPR) and decreased PA acceleration time (PAAT) (p&lt;0.05). MCT rats developed RVF characterized by increased RV end diastolic volume (EDV), decreased CO, TAPSE and ventricular-arterial decoupling (decreased Emax/Ea ratio) (p&lt;0.05). SuHx rats had adaptive RVH. RNAsequencing revealed 2,547 differentially regulated transcripts. Functional Annotation analysis revealed multiple enriched GOterms, the most significant of which described mitochondrion (GO: 0005739; p=1.6E-53 which describes 414 genes). Significant GOterms also include mitochondrial inner membrane (GO: 0005743; p=3.9E-20) and mitochondrial respiratory chain complex I (GO: 0005747 ; p=4.9E-10). We validated 15 key dysregulated mitochondrial genes in maladaptive RVH (MCT; n=7) compared to both adaptive RVH (SuHx; n=4) and Ctrl (n=12) by qPCR, Finally, we validated these findings in human samples from PAH patients with RVH compared to controls (n=5 per group; p&lt;0.05). Conclusion: We combined haemodynamic investigation and transcriptomics to identify specific mitochondrial-metabolic gene expression signatures associated with RVF in two different preclinical models and in human samples.
Abstract 18855: Hemoadsorption Removes Systemic Cytokines After Experimental Cardiac Arrest in Rats: A Dose-finding Study
Authors: Elizabeth B Snajdar, John A Kellum, Jason P Stezoski, Kyle S Simqu, Keri Janesko-Feldman, Patrick M Kochanek, Tomas Drabek
Journal: Circulation (2017)

Introduction: Cardiac arrest (CA) triggers post-CA syndrome (PCAS) with complex pathophysiological mechanisms resembling sepsis. Hemoadsorption (HA) is a novel technique designed to remove circulat...
INTRAVASCULAR ULTRASOUND PREDICTORS OF 4-YEAR CLINICAL OUTCOMES FOLLOWING ABSORB BIORESORBABLE SCAFFOLD IMPLANTATION: INSIGHTS FROM THE ABSORB JAPAN TRIAL
Authors: Takeshi Nishi, Kozo Okada, Hideki Kitahara, Ryo Kameda, Masayasu Ikutomi, Brooke Hollak, Paul Yock, Jeffrey Popma, Hajime Kusano, Wai-Fung Cheong, Krishnankutty Sudhir, Peter Fitzgerald, Yasuhiro Honda, Takeshi Kimura
Journal: Journal of the American College of Cardiology (2019)
OUTCOMES OF ISCHEMIC TESTING PRIOR TO ABLATION FOR SUSTAINED MONOMORPHIC VENTRICULAR TACHYCARDIA
Authors: Christopher Schumann, Evan Harmon, Andrew Darby, Rohit Malhotra, John DiMarco, Pamela Mason, Kenneth Bilchick, James Mangrum, John Ferguson, Nishaki Mehta
Journal: Journal of the American College of Cardiology (2019)
IMPACT OF ATRIAL FIBRILLATION ABLATION ON LEFT ATRIUM FUNCTIONALITY ASSESSED BY VOLUME-PRESSURE LOOPS
Authors: Antonios Karanasos, Konstantinos Toutouzas, Kostas Tyrovolas, Michael Efremidis, Dimitris Tsiachris, Athanasios Kordalis, Maria Karmpalioti, Constantina Aggeli, Christodoulos Stefanadis, Kostas Gatzoulis, Dimitris Tousoulis
Journal: Journal of the American College of Cardiology (2019)
Abstract 375: Defining a Unifying Mechanism for Select Cardiomyopathy-Linked Variants of Desmoplakin
Authors: Maegen Ackermann, Heather Manring, Ronald Ng, Taylor Albertelli, Prameela Jyothi Bobbili, Tyler Stevens, Daniel Jacoby, Paul Janssen, Ahmet Kilic, Nathan Wright, Nathan Wright, Yibing Qyang, Stuart Campbell
Journal: Circulation Research (2018)

Arrhythmogenic cardiomyopathy (AC) is a disease that affects 1 in 2000 Americans every year and segregates with sudden cardiac death (SCD). AC is linked to genetic variants in desmosomal genes, however the molecular mechanisms underlying AC remain unclear. To probe the mechanisms of an AC-linked desmosomal mutation, we identified a candidate family with a history of SCD and an unknown variant (R451G) in the desmoplakin (DSP) gene. Statistically significant linkage between the R451G-variant and symptomatic family members (LOD score = 3.4) was established and heart autopsy tissue from a genotype-phenotype positive family member revealed pronounced fibrofatty scarring and a significant loss of DSP protein at the intercalated disc (ID). Notably, the R451G-variant sits in a pocket containing several clinical DSP variants and we show that endogenous DSP is cleaved via a calpain-dependent mechanism. Together this led us to hypothesize that mutant DSP is more susceptible to calpain cleavage, resulting in cellular haploinsufficiency. To define a unifying mechanism for AC-linked variants, we assessed the biomolecular properties of DSP variants. While these variants do not significantly perturb the global structure of DSP, there are significant changes to local stabilizing intramolecular interactions of select variants, which correlates with augmented calpain degradation due to increased exposure of an auto-inhibited calpain-cleavage site. Taken together we have identified a unifying mechanism for select AC-linked variants of DSP grounded in increased susceptibility to calpain-cleavage leading to decreased functional DSP. To test the hypothesis that DSP haploinsufficiency results in poor ID organization and reduced electrical conduction of the myocardium we created engineered heart tissues (EHTs) from induced pluripotent stem cells generated from a symptomatic R451G-positive family member. Surprisingly, we found that conduction velocities were unchanged however, mutant tissues had a significantly slower rate of contraction despite unchanged peak contractile force. This biomechanical deficiency in DSP haploinsuffient cells may indicate poor coupling between the sarcomere lattice and the ID as a fundamental disease mechanism in AC.
INCORPORATION OF MITRAL ANNULAR PLANE SYSTOLIC EXCURSION (MAPSE) AND TRICUSPID ANNULAR PLANE SYSTOLIC EXCURSION (TAPSE) FOR RISK STRATIFICATION OF ACUTE PULMONARY EMBOLISM
Authors: Isabel C. Balachandran, Jason Matos, Benedikt Heidinger, Donya Mohebali, Stephanie Feldman, Ian McCormick, Diane Litmanovich, Warren J. Manning, Brett Carroll
Journal: Journal of the American College of Cardiology (2019)
A RARE CASE OF COMPLEX VENTRICULAR SEPTAL ANEURYSM IN ASSOCIATION WITH BICUSPID AORTIC INSUFFICIENCY IN AN ADULT PATIENT
Authors: Arman Kalamkarian, Balaji Natarajan, Amish Patel, Suneel Kumar, Mir Wasif Ali, Ramdas Pai
Journal: Journal of the American College of Cardiology (2019)
Molecular Support for Heterogonesis Resulting in Sesquizygotic Twinning
Authors: Michael T. Gabbett, Johanna Laporte, Renuka Sekar, Adayapalam Nandini, Pauline McGrath, Yadav Sapkota, Peiyong Jiang, Haiqiang Zhang, Trent Burgess, Grant W. Montgomery, Rossa Chiu, Nicholas M. Fisk
Journal: New England Journal of Medicine (2019)

Sesquizygotic multiple pregnancy is an exceptional intermediate between monozygotic and dizygotic twinning. We report a monochorionic twin pregnancy with fetal sex discordance. Genotyping of amniotic fluid from each sac showed that the twins were maternally identical but chimerically shared 78% of their paternal genome, which makes them genetically in between monozygotic and dizygotic; they are sesquizygotic. We observed no evidence of sesquizygosis in 968 dizygotic twin pairs whom we screened by means of pangenome single-nucleotide polymorphism genotyping. Data from published repositories also show that sesquizygosis is a rare event. Detailed genotyping implicates chimerism arising at the juncture of zygotic division, termed heterogonesis, as the likely initial step in the causation of sesquizygosis.
Implication of Hypoxia-Inducible Factor-1 (HIF-1) As a New Therapeutic Target in JAK2V617F Positive Myeloproliferative Neoplasms (MPN)
Authors: Julian Baumeister, Nicolas Chatain, Annika Hubrich, Caroline Küstermann, Stephanie Sontag, Kristin Seré, Martin Zenke, Tim H Brümmendorf, Kamil Kranc, Steffen Koschmieder, Deniz Gezer
Journal: Blood (2018)
Abstract 214: A Microrna-hippo Pathway Functions in Cardiac Conduction System Homeostasis and Regeneration
Authors: Jun Wang
Journal: Circulation Research (2018)

The cardiac conduction system (CCS) is required for initiating and maintaining regular rhythmic heartbeats. CCS defects can give rise to cardiac arrhythmia, a leading cause for morbidity worldwide. Hippo signaling, a known organ size and growth regulator, has recently been shown to inhibit cardiomyocyte proliferation and renewal. However, the role for Hippo signaling in the CCS is unknown. Here, we found that adult mice display cardiac arrhythmias when Hippo signaling is specifically disrupted in the CCS, indicating an important role for Hippo in maintaining CCS homeostasis. We discovered that miR-17-92 represses Hippo signaling by directly repressing Lats2 , a core Hippo pathway component and that Hippo activity is increased in miR-17-92 deleted hearts. Importantly, disruption of miR-17-92 in the CCS gives rise to cardiac arrhythmias in adult mice. Notably, specific injury of the CCS causes severe lethal cardiac arrhythmias, whereas inactivation of Lats efficiently rescues the phenotype. In addition, based on data from the chromatin immunoprecipitation deep sequencing with an antibody against the Hippo signaling effector Yap, we found that Hippo signaling regulates genes involved in the CCS homeostasis and regeneration. Together, our findings indicate that maintenance of CCS homeostasis requires proper levels of Hippo signaling, and that repression of Hippo signaling protects the hearts from CCS damage and subsequent arrhythmogenesis.
CORONARY ARTERY CALCIUM IS A STRONG AND INDEPENDENT PREDICTOR OF MAJOR ADVERSE CARDIOVASCULAR EVENTS IN PATIENTS REFERRED FOR NON-CONTRAST CT FOR NON-CARDIAC INDICATIONS
Authors: Dahlia Banerji, Raza M. Alvi, Alexander Ivanov, Romina Sotoodeh, Devvora Olalere, Emma Will, John S. Aluru, Stephanie K. Bogdan, Michael Osborne, Michael Lu, Udo Hoffmann
Journal: Journal of the American College of Cardiology (2019)
Abstract 397: Preventing Cardiomyopathy of Muscular Dystrophy Through Antagonism of the Thromboxane/Prostanoid Receptor
Authors: Erica J Carrier, Cristi L Galindo, Kyungsoo Kim, Ines Macias-Perez, Leo Pavliv, Jonghyun J Shin, Bjorn C Knollmann, Jonathan H Soslow, Larry W Markham, James D West
Journal: Circulation Research (2018)

Muscular dystrophy causes mechanical damage and increased membrane permeability of cardiomyocytes, leading to progressive cardiomyopathy and diffuse myocardial fibrosis that typically begins in the free wall of the LV. Cardiac dysfunction is a primary cause of death in Duchenne (DMD) and other muscular dystrophy (MD) patients. Activation of the thromboxane/prostanoid (TP) receptor increases calcium transients in cardiomyocytes, causes arrhythmia, and is pro-fibrotic. We thus hypothesized that TP receptor activation contributes to the cardiac phenotype of MD, and that blockade of the TP receptor would improve cardiac fibrosis and function in mouse MD models. We gave 3 different mouse models of MD either normal drinking water or water containing 25 mg/kg/day of the TP receptor antagonist ifetroban, from weaning to the predetermined endpoint. TP receptor antagonism improved 10-week survival from 60% to 100% in utrophin/dystrophin double knockout mice, a model of severe DMD, and increased cardiac output compared with surviving vehicle-treated mice. In the mdx/mTR mouse model of DMD, treatment with ifetroban likewise improved 6-month survival from 43% to 100% and increased cardiac output. Finally, we examined delta-sarcoglycan knockout (dSG KO) male mice, a model of limb-girdle muscular dystrophy (LGMD) that replicates the DMD cardiac phenotype with improved survival. TP receptor antagonism normalized fractional shortening, ejection fraction, and LVSP in dSG KO mice, and decreased plasma ANP. However, it had no effect on the contraction deficits of isolated cardiomyocytes other than to normalize the slowed relaxation of dSG KO. Ifetroban-treated mice had improved myocardial, but not skeletal muscle fibrosis. This was most noticeable in the LV free wall and occurred in conjunction with decreased TGF-beta activity and normalized plasma WBC. Typical of DMD cardiomyopathy, dSG KO hearts had reduced expression of neuronal nitric oxide synthase (nNOS) and claudin-5, which was improved with TPr antagonism. The results of our studies indicate that TP receptor activation may contribute to MD cardiomyopathy, and oral antagonism of the TP receptor may be a novel therapeutic for the cardiac phenotype in DMD and LGMD patients.
Multiple Lip Papules and Nodules in an Adult Man
Authors: Nathaniel Smith, Earl Glusac, Jonathan Leventhal
Journal: JAMA Dermatology (2019)

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P115/O19 Immunomodulatory activity of adipose-derived mesenchymal stem cells of ankylosing spondylitis patients
Authors: E Kuca-Warnawin, U Skalska, I Janicka, K Bonek, P Głuszko, W Maslinski, E Kontny
Journal: Annals of the Rheumatic Diseases (2019)

<h3>Career situation of first and presenting author</h3> Post-doctoral fellow. <h3>Introduction</h3> Ankylosing spondylitis (AS) is a chronic autoimmune disease characterized by inflammation and pathological new bone formation at axial joints with resulting spinal segments fusion. The immune abnormalities observed in AS patients concern mainly T lymphocytes and manifest by increased numbers of circulating Th17 cells and defects of regulatory T (Treg) cells. Adipose mesenchymal stromal/stem cells (ASCs) exert immunosuppressive effects on different immune cells, including T lymphocytes, and may be promising option for successful therapy of AS. <h3>Objectives</h3> In this study we have focused on immunoregulatory activity of ASCs from AS patients (AS/ASCs) toward healthy donor peripheral blood mononuclear cells (PBMCs) and T lymphocytes with special regard to Th17 and Treg cell subsets. <h3>Methods</h3> AS/ASCs of 15 AS patients and commercially available ASC lines from healthy donors (hASC) were used. ASCs were co-cultured with either anti-CD3/CD28-stimulated CD4<sup>+</sup> T lymphocytes or mitogen-stimulated PBMCs of allogeneic healthy volunteers. Expression of CD25 and FoxP3 transcription factor in T cells and these cells proliferation were evaluated by flow cytometry. Concentrations of cytokines associated with Th1 (IFNγ), Th17 (IL-17AF) or Treg (IL-10, TGFß) cells as well as of factors related to immunomodulatory function of ASCs (PGE<sub>2</sub>, kynurenines) were measured by ELISAs in co-culture supernatants. <h3>Results</h3> In the co-cultures of ASCs with PBMCs both hASCs and AS/ASCs exerted similar inhibitory effect on the proliferation response of T CD4<sup>+</sup> and CD8<sup>+</sup> cells. Similar results were obtained in co-cultures of ASCs with purified T CD4<sup>+</sup> cells. In the co-cultures of hASCs and AS/ASCs with PBMCs as well as with purified T CD4<sup>+</sup> cells the significant increases of kynurenines and PGE<sub>2</sub> production were observed. In co-cultures of ASCs and PBMCs there was a marked decrease of IFNg and significant increase of IL-17AF. Concomitantly, Treg proportion in these co-cultures was elevated. In contrary, in the co-cultures of activated T CD4<sup>+</sup> cells with ASCs there was some increase of IFNg and IL-17AF whereas Treg proportion was downregulated. <h3>Conclusions</h3> AS/ASCs and hASCs exert comparable effects on T cells. Since different effects were observed in the co-cultures of ASCs with PBMCs than with CD4<sup>+</sup> cells, it seems that ASCs activity toward Th17 and Treg cells is dependent on the presence of accessory cells. <h3>Acknowledgements</h3> This work was supported by the National Science Centre in Poland (Grant No. 2016/21/B/NZ5/00500) and by the NIGRiR Statutory Grant (Grant No. S/6). <h3>Disclosure of Interest</h3> None declared.
MITRAL REGURGITATION BEFORE TRANSCATHETER AORTIC VALVE IMPLANTATION FOR AORTIC STENOSIS AND MORTALITY: A META-ANALYSIS AND SYSTEMATIC REVIEW
Authors: Ankur Sethi, Vamsi Kodumuri, Yash Singbal, Vinoy Prasad, Ashok Chaudhary, John Kassotis
Journal: Journal of the American College of Cardiology (2019)
LONG-TERM MORTALITY WITH MULTIVESSEL VERSUS CULPRIT-LESION-ONLY PERCUTANEOUS CORONARY INTERVENTION IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION AND CARDIOGENIC SHOCK: INSIGHTS FROM AN UPDATED META-ANALYSIS
Authors: Amartya Kundu, Partha Sardar, Rohit Malhotra, Nikolaos Kakouros, Daniel Fisher
Journal: Journal of the American College of Cardiology (2019)
INDEPENDENT PROGNOSTIC VALUES OF CLINICAL RISK SCORES, RIGHT VENTRICULAR SYSTOLIC PRESSURE, AND N-TERMINAL PRO-B-TYPE PEPTIDE IN HEART FAILURE WITH PRESERVED EJECTION FRACTION: INSIGHTS FROM SUPERVISED AND UNSUPERVISED MODELS
Authors: Maxime Tremblay-Gravel, Yukari Kobayashi, Kalyani Boralkar, Xiao Li, Sara Bouajila, Tomoko Nishi, Myriam Amsallem, Kegan Moneghetti, Mona Selej, Mehmet Ozen, Utkan Demirci, Euan A. Ashley, Matthew Wheeler, Kirk Knowlton, Tatiana Kouznetsova, Francois Haddad
Journal: Journal of the American College of Cardiology (2019)
PROGNOSTIC ROLE OF HLM CLASSIFICATION IN PATIENTS WITH HEART FAILURE UNDERGOING TRANSCATHETER VALVE INTERVENTION
Authors: Paolo Severino, Marco Martello, Mariateresa Pucci, Rossana Scarpati, Maria Alfarano, Fabio Infusino, Simone Calcagno, Sara Cimino, Viviana Maestrini, Massimo Mancone
Journal: Journal of the American College of Cardiology (2019)
CLINICAL AND LABORATORY PREDICTORS FOR PLAQUE EROSION IN PATIENTS WITH ACUTE CORONARY SYNDROMES
Authors: Erika Yamamoto, Francesco Fracassi, Tomoyo Sugiyama, Taishi Yonetsu, Tsunekazu Kakuta, Tsunenari Soeda, Yoshihiko Saito, Bryan P. Yan, Osamu Kurihara, Masamichi Takano, Giampaolo Niccoli, Takumi Higuma, Shigeki Kimura, Yoshiyasu Minami, Junya Ako, Tom Adriaenssens, Niklas Boeder, Holger Nef, Hang Lee, Filippo Crea, Takeshi Kimura, James Fujimoto, Valentin Fuster, Ik-Kyung Jang
Journal: Journal of the American College of Cardiology (2019)