tbuckley/cabot-search huggingface dataset:
DIAGNOSTIC ACCURACY OF ADVANCED IMAGING IN CARDIAC SARCOIDOSIS: AN IMAGING-HISTOLOGIC CORRELATION STUDY IN PATIENTS UNDERGOING CARDIAC TRANSPLANTATION
Authors: Sanjay Divakaran, Garrick Stewart, Neal Lakdawala, Robert Padera, Wunan Zhou, Akshay Desai, Michael Givertz, Mandeep Mehra, Raymond Kwong, Brian B. Ghoshhajra, Viviany R. Taqueti, Hicham Skali, Sharmila Dorbala, Ron Blankstein, Marcelo Di Carli
Journal: Journal of the American College of Cardiology (2019)
Systemic Vascular Basement Membrane Markers Linked to Synovial Vascular Remodeling Are Bio-Markers of Hemarthrosis in Patients with Hemophilia
Authors: Srila Gopal, Esther J Cooke, Jenny Y Zhou, Ilana Levin, Pamela Emery, Tina Manon- Jensen, Morten Karsdal, Annette von Drygalski
Journal: Blood (2018)
Effect of MDV3100, a novel androgen receptor signaling inhibitor, on cell proliferation and tumor size in an apocrine breast cancer xenograft model.
Authors: Sebastián Bernales, Javier Guerrero, Francisco Gómez, Iván E. Alfaro, Andrew A Protter
Journal: Journal of Clinical Oncology (2012)

3072 Background: MDV3100, a new androgen receptor (AR) signaling inhibitor, has demonstrated therapeutic effects in men with post-docetaxel prostate cancer (AFFIRM). AR is also expressed in the majority of breast cancers. Molecular profiling of estrogen receptor negative (ER-) breast cancer classifies this disease into basal and molecular apocrine subtypes. Apocrine breast cancer represents ~50% of ER- tumors and is characterized by a steroid response gene signature that includes AR expression. Here we report the effects of MDV3100 on the growth of the ER-/AR+ breast cancer cell line MDA-MB-453 in tissue culture and in an in vivo xenograft mouse model. Methods: MDA-MB-453 cells were maintained in 5% complete or 5% charcoal-stripped serum supplemented with dihydrotestosterone (CSS-DHT). The DHT induced nuclear translocation of AR was determined by subcellular fractionation followed by western blot. AR target gene expression was measured by qPCR. To generate a mouse xenograft model, 5-6 wk old female NOD-SCID-IL2Rgc–/– mice were injected ortotopically with 6x10 6 MDA-MB-453 cells into the fourth inguinal gland and were administered exogenous DHT (12.5 mg in a 60 day release pellet) or control pellets. When tumor size reached 100 mm 3 , mice were treated with 10 mg/kg/day MDV3100 or vehicle (0.5% methocel solution) by oral gavage for 33 days. Results: Viability of MDA-MB-453 cells treated with 10 uM MDV3100 was reduced by 10% after 3 days and 27% after 6 days. Treatment with 25 uM MDV3100 reduced cell viability by 27% after 3 days and 36% after 6 days. Similar results were obtained when cells maintained in CSS-DHT were treated with MDV3100. Treatment with MDV3100 blocked DHT-induced nuclear translocation and concordantly reduced the expression of AR-targets fatty acid synthase, prolactin receptor, and gross cystic disease protein-15. In the xenograft model, MDV3100 inhibited tumor growth by 78% as compared to tumors treated with vehicle. Conclusions: MDV3100 reduced cell proliferation in apocrine cell lines. MDV3100 also suppressed exogenous DHT-induced growth of ER-/AR+ tumors in vivo. These results support the evaluation of MDV3100 as a treatment for apocrine tumors.
EFFECT OF SYSTEMIC INFLAMMATION ON OUTCOMES AFTER COMPLEX PERCUTANEOUS CORONARY INTERVENTION
Authors: Anton Camaj, Gennaro Giustino, Bimmer Claessen, Tim Hinohara, Usman Baber, Melissa Aquino, Paul Guedeney, Sabato Sorrentino, Deborah Kalkman, Birgit Vogel, Serdar Farhan, Srushti Shah, Nitin Barman, Pooja Vijay, Jason Kovacic, Joseph Sweeny, George Dangas, Annapoorna Kini, Roxana Mehran, Samin Sharma
Journal: Journal of the American College of Cardiology (2019)
BLOOD PRESSURE VARIABILITY AND CLINICAL CHARACTERISTICS OF PATIENTS HOSPITALIZED FOR ACUTE MYOCARDIAL INFARCTION
Authors: Konstantinos P. Tsioufis, Konstantinos Konstantinou, Dimitris Konstantinidis, Ioannis Leontsinis, Christos Fragoulis, Kyriakos Dimitriadis, Alexandros Kasiakogias, Manos Mantzouranis, Dimitris Tousoulis
Journal: Journal of the American College of Cardiology (2019)
CURRENT SURGICAL RISK SCORES OVERESTIMATE THE RISK ASSOCIATED WITH MINIMALLY INVASIVE AORTIC VALVE REPLACEMENT IN LOW-RISK PATIENTS
Authors: Ahmed Alnajar, Subhasis Chatterjee, Brenden Chou, Mariam Khabsa, Madeline Rippstein, Vei Vei Lee, Angelo La Pietra, Joseph Lamelas
Journal: Journal of the American College of Cardiology (2019)
THE INFLUENCE OF MICROVASCULAR DISEASE ON CARDIOVASCULAR EVENTS IN TYPE 2 DIABETES: A POST HOC ANALYSIS OF EMPA-REG OUTCOME
Authors: Subodh Verma, Christoph Wanner, Isabella Zwiener, Anne Pernille Ofstad, Jyothis T. George, David Fitchett, Bernard Zinman
Journal: Journal of the American College of Cardiology (2019)
TEMPORAL CHANGES IN CORONARY NON-CULPRIT HEMODYNAMIC INDICES AFTER ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION: RESULTS FROM THE REDUCE-MVI TRIAL
Authors: Nina Willemijn van der Hoeven, Gladys N. Janssens, Guus Waard, Henk Everaars, Christopher Broyd, Casper W.H. Beijnink, Peter van de Ven, Robin Nijveldt, Christopher Cook, Ricardo Petraco, Tim Ten Cate, Clemens von Birgelen, Javier Escaned, Justin Davies, Maarten Van Leeuwen, Niels van Royen
Journal: Journal of the American College of Cardiology (2019)
Oral Abstracts (Abstracts 1–263)
Authors: Romain Desert, Christelle Reynes, Rodolphe Sabatier, Damien Gregoire, Florian Rohart, A. Corlu, Frédéric Canal, Marie Sicard, Mireille Desille, Stéphanie Renaud, Bruno Turlin, L. Sulpice, Damien Bergeat, Pascale Bellaud, Christine Perret, Bruno Clément, Kim-Anh Lê Cao, Orlando Musso
Journal: Hepatology (2017)

AASLD Publications Hepatology Liver Transplantation Clinical Liver Disease Hepatology Communications AASLD Publications Hepatology Liver Transplantation Clinical Liver Disease Hepatology Communications
ECHOCARDIOGRAPHIC MYOCARDIAL STRAIN IMAGING AND TROPONIN T FOR EARLY DETECTION OF CARDIOTOXICITY IN PATIENTS RECEIVING ANTHRACYCLINES
Authors: Kazuko Tajiri, Hiroko Bando, Nobutaka Tasaka, Shigeru Chiba, Kazutaka Aonuma, Ikuo Sekine, Masaki Ieda
Journal: Journal of the American College of Cardiology (2019)
Senior male leaders must act as allies to help women succeed, says report
Authors: Abi Rimmer
Journal: BMJ (2019)

Gender equality at all levels of the NHS workforce will only be achieved if men act as allies to women, a new report has argued.

The report, launched to coincide with International Women’s Day, gathered views from men in senior leadership roles across the NHS.1

It was published by the Health and Care Women Leaders Network, which was created in 2015 to bring together senior and aspiring women leaders.

Samantha Allen, chair of the network, said men needed to understand the barriers women faced in the …
OUTCOMES OF PERCUTANEOUS CORONARY INTERVENTIONS IN OCTOGENARIANS VERSUS NONAGENARIANS
Authors: Upasana Banerjee, Sidhanta Gurung, Konstantinos Charitakis, H. Vernon Anderson, Salman Arain, Prakash Balan, Richard Smalling, Abhijeet Dhoble
Journal: Journal of the American College of Cardiology (2019)
STRUCTURAL INEQUITIES IN THE ADMISSION PATTERNS OF PATIENTS WITH HEART FAILURE TO GENERAL MEDICINE OR CARDIOLOGY SERVICES
Authors: Lauren A. Eberly, Aaron G. Richterman, Bram Wispelwey, Jennifer Goldsmith, Robert B. Boxer, Katherine C. Brooks, Robert Glynn, Joseph Loscalzo, Michelle Morse, Eldrin Lewis
Journal: Journal of the American College of Cardiology (2019)
SAFETY AND EFFICACY OF INTRAVENOUS DILTIAZEM IN ATRIAL FIBRILLATION WITH RAPID VENTRICULAR RESPONSE IN THE INPATIENT ENVIRONMENT
Authors: Ilya Ryaboy, Cyrus A. Askin, Ardalon Farhat-Sabet, Raymond Fisher, Kevin K. Chung, Kelvin Bush, Dustin Thomas
Journal: Journal of the American College of Cardiology (2019)
Abstract 455: Role of Transcription Co-Factor Friend of GATA 2 (FOG2) in a Hypertensive-Diabetic Mouse Model of Coronary Microvascular Disease
Authors: Marie A Guerraty, Hannah J Szapary, Zoltan Arany, Daniel J Rader
Journal: Circulation Research (2018)

Coronary microvascular disease (CMVD) - disease of the coronary pre-arterioles, arterioles, and capillaries – has become an increasingly well-recognized cardiac pathology. Characterized by microvascular remodeling, wall thickening, lumen obliteration, endothelial dysfunction, capillary rarefaction, and perivascular immune cell infiltration, it can lead to inadequate myocardial perfusion, angina, heart failure, or myocardial infarction. Despite these clinical ramifications, our understanding of the pathophysiology of CMVD remains nascent. Friend of GATA 2 (FOG2, also called ZFPM2) is a transcriptional co-factor which is crucial in coronary development; and cardiomyocyte expression of FOG2 is required for the maintenance of the coronary microvasculature in adult mice. We hypothesize that FOG2 is activated in CMVD, and that Hypoxia-Inducible Factor 1a (HIF1a) may play a role in FOG2 activation. To test this hypothesis, we developed a hypertensive-diabetic (HTN/DM) mouse model of CMVD. Briefly, adult female C57BL/6 mice were treated with Angiotensin II (1mg/kg/day SQ osmotic pump for 8 weeks) and low-dose streptozotocin (35 mg/kg IP for 4 days) (n=5) or saline (n=4). HTN/DM mice had increased systolic blood pressure (141.7±1.6 vs 109.2±1.1 mmHg, p&lt;0.0001), mild fasting hyperglycemia (181.8±8.5 vs 148.8±9.8 mg/dl, p=0.04), and decreased glucose tolerance (p&lt;0.0003). HTN/DM mice had evidence of mild LV hypertrophy, preserved EF, and diminished coronary hyperemic velocities by echocardiography. Histology revealed microvascular pathology (vessel wall thickening and immune cell infiltration) and decreased cardiac capillary density (148.8±9.8 vs 163.8±4.3 phf, p=0.008). FOG2 protein was increased in HTN/DM mouse hearts (p&lt;0.05). Treatment of AC16 cardiomyocytes with HIF-activator hydroxylase inhibitor DMOG showed a dose-dependent increase in FOG2 expression and protein nuclear translocation. In summary, we modeled CMVD in mice using mild hypertensive-diabetic insults which are relevant to human disease. We found that FOG2 protein is increased in CMVD suggesting that FOG2 may be relevant to adult CMVD pathophysiology in vivo . We additionally provide in vitro evidence that FOG2 is induced in HIF-activating conditions .
MECHANISTIC INSIGHT INTO THE ROLE OF THE VON WILLEBRAND FACTOR-ANGIOPOIETIN-AXIS IN PULMONARY ARTERIOVENOUS MALFORMATIONS IN CHILDREN WITH A GLENN CIRCULATION
Authors: Carlo R. Bartoli, Samson Hennessy-Strahs, Abigail Waldron, Kevin K. Whitehead, J. William Gaynor, Andrew Glatz
Journal: Journal of the American College of Cardiology (2019)
P097 Intracellular interleukin-1 receptor antagonist released upon cell death acts as an alarmin inhibitor in aldara cream-induced psoriasis-like skin inflammation
Authors: P Martin, G Palmer, E Rodriguez, J Palomo, C Gabay
Journal: Annals of the Rheumatic Diseases (2019)

<h3>Career situation of first and presenting author</h3> Post-doctoral fellow. <h3>Introduction</h3> The inflammatory effects of interleukin (IL)-1 are tightly controlled by IL-1 receptor antagonist (IL-1Ra), which blocks the binding of both IL-1α and IL-1β to IL-1R1. Four IL-1Ra isoforms are produced from the same gene by the use of different first exons, alternative mRNA splicing and translation initiation sites. One IL-1Ra isoform is secreted (sIL-1Ra), whereas the three others are intracellular (icIL-1Ra1, 2, 3) due to the absence of a signal peptide. In contrast to the well-characterized function of the secreted isoform, the biological role of the intracellular isoforms remains largely unclear. The icIL-1Ra1 isoform is constitutively expressed and represents the major isoform in keratinocytes. <h3>Objectives</h3> To investigate the role of icIL-1Ra1 in a mouse model of psoriasis-like skin inflammation induced by Aldara cream, an FDA-approved drug with the active ingredient imiquimod, a toll-like receptor 7 agonist. <h3>Methods</h3> We generated a mouse line specifically lacking icIL-1Ra1, in which expression of the other three IL-1Ra isoforms was not affected. Psoriasis-like skin inflammation was induced on mouse ears by the topical application of Aldara cream. Skin inflammation was assessed using a caliper to measure ear thickness. Ear mRNA levels of cytokines were measured by real-time PCR. An intracellular or extracellular role of icIL-1Ra1 was investigated <i>ex vivo</i> on ear biopsies and <i>in vitro</i> in primary keratinocytes by real-time PCR or ELISA. <h3>Results</h3> Naïve icIL-1Ra1 deficient mice exhibited a normal phenotype. However icIL-1Ra1 deficiency resulted in an enhanced severity of Aldara cream-induced skin inflammation as demonstrated by increased ear thickness. In addition, mRNA levels of several pro-inflammatory cytokines were significantly increased in icIL-1Ra1 deficient mice as compared to wild-type (WT) littermates. By immunofluorescence IL-1Ra was detected only in keratinocytes of naïve and Aldara-treated WT mice, but totally absent in icIL-1Ra1 deficient mice. Using ear biopsies and keratinocytes from WT mice, we observed that Aldara cream led to the release of both icIL-1Ra1 and the alarmin IL-1α, accompanied by caspase 1/11-independent cell lysis. Injection of neutralizing anti-IL-1α antibodies into Aldara-treated icIL-1Ra1 deficient mice significantly reduced the severity of skin inflammation. <h3>Conclusions</h3> These data suggest that icIL-1Ra1 is stocked in keratinocytes in order to immediately counteract the inflammatory effects of IL-1α that is released upon cell lysis, thus acting as an intrinsic alarmin inhibitor. <h3>Disclosure of Interest</h3> None declared.
Retinal Detachment after Phakic Intraocular Lens Implantation: A 10-Year Multicenter Study
Authors: Pukhraj Rishi, Yamini Attiku, Manisha Agarwal, Raja Narayanan, Dinesh Talwar, Bhaskar Srinivasan, Abhinav Dhami, Ekta Rishi
Journal: Ophthalmology (2019)
Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer
Authors: Kirsten L. Bryant, Clint A. Stalnecker, Daniel Zeitouni, Jennifer E. Klomp, Sen Peng, Andrey P. Tikunov, Venugopal Gunda, Mariaelena Pierobon, Andrew M. Waters, Samuel D. George, Garima Tomar, Björn Papke, G. Aaron Hobbs, Liang Yan, Tikvah K. Hayes, J. Nathaniel Diehl, Gennifer D. Goode, Nina V. Chaika, Yingxue Wang, Guo-Fang Zhang, Agnieszka K. Witkiewicz, Erik S. Knudsen, Emanuel F. Petricoin, Pankaj K. Singh, Jeffrey M. Macdonald, Nhan L. Tran, Costas A. Lyssiotis, Haoqiang Ying, Alec C. Kimmelman, Adrienne D. Cox, Channing J. Der
Journal: Nature Medicine (2019)
Response to direct-acting antiviral therapy among ongoing drug users and people receiving opioid substitution therapy
Authors: Juan Macías, Luis E. Morano, Francisco Téllez, Rafael Granados, Antonio Rivero-Juárez, Rosario Palacios, MªJosé Ríos, Dolores Merino, Montserrat Pérez-Pérez, Antonio Collado, Blanca Figueruela, Aitana Morano, Carolina Freyre-Carrillo, José M. Martín, Antonio Rivero, Federico García, Juan A. Pineda
Journal: Journal of Hepatology (2019)
Is microvessel density a good prognostic factor in colorectal cancer ? Meta-analysis of the literature
Authors: Gaetan Des Guetz, Bernard Uzzan, Jean-Francois Morere, Patrick Nicolas, Michel Cucherat, Jean-Luc Breau, Gérard Perret
Journal: Cancer Research (2005)

1175  We performed a meta-analysis of all 40 published studies relating intratumoral microvessel density (MVD), reflecting angiogenesis, to relapse free survival (RFS) and overall survival (OS) in colorectal cancer (CRC), following a previous similar work in breast cancer (Cancer Res., 2004, 64, 2941-2955). For each study, MVD impact was measured by risk ratio (RR) between the two survival distributions with median MVD as cut off. Four studies did not mention survival data or fit inclusion criteria, 4 corresponded to multiple publications of same series, leaving 32 independent studies (3496 patients; mean age : 64.7 years). MVD was assessed by immunohistochemistry, using antibodies against factor VIII (16 studies; 1886 patients), CD31 (10 studies; 986 patients) or CD34 (7 studies; 907 patients). Statistical calculations were performed for MVD in 22 studies, including 11 studies (n = 1268) for RFS and 16 for OS (n = 2072). High MVD significantly (p
Prognostic Impact of Activating Mutations of the NRAS/KRAS Genes in Patients with Primary and Post-Essential Thrombocythemia (ET)/Polycythemia Vera (PV) Myelofibrosis (MF)
Authors: Fabio PS Santos, Bartlomiej Getta, Lucia Masarova, Christopher Famulare, Jessica Schulman, Renato D Puga, Raquel de Melo Alves Paiva, Nelson Hamerschlak, Hagop M. Kantarjian, Ross L. Levine, Paulo Vidal Campregher, Raajit K. Rampal, Srdan Verstovsek
Journal: Blood (2018)
FUNCTIONAL CAPACITY MEASURED BY THE SHORT PHYSICAL PERFORMANCE BATTERY (SPPB) AND NOT CARDIAC PARAMETERS ARE INDEPENDENTLY ASSOCIATED WITH QUALITY OF LIFE IN PATIENTS WITH TRANSTHYRETIN CARDIOMYOPATHY
Authors: Samantha Guadalupe, Sergio Teruya, Stephen Helmke, Jeffeny De Los Santos, Mathew Maurer, Adam Castano
Journal: Journal of the American College of Cardiology (2019)
CLINICAL IMPACT OF ACUTE KIDNEY INJURY IN PATIENTS WITH LEFT VENTRICULAR ASSIST DEVICES: ANALYSIS FROM A US NATIONAL DATABASE
Authors: Mohit Pahuja, Sagar Ranka, Vicken Zeitjian, Omar Chehab, Tushar Mishra, Hossam Abubakar, Ahmed Yassin, Shruti Mony, Manmohan Singh, Mohamed Shokr, Alexandros Briasoulis, Luis Afonso
Journal: Journal of the American College of Cardiology (2019)
IMPACT OF ADVERSE RIGHT VENTRICULAR REMODELING ON MORTALITY IN IDIOPATHIC PULMONARY ARTERIAL HYPERTENSION
Authors: Ioulia Grapsa, Timothy Tan, Maria do Carmo Nunes, Declan O'Regan, Giuliana Durighel, Luke S.G.E. Howard, Simon J.R. Gibbs, Petros Nihoyannopoulos
Journal: Journal of the American College of Cardiology (2019)
Abstract 531: A Lack in Endogenous Proteasome Regulation Provokes Exacerbated Cardiac Remodeling and Premature Heart Failure Following Catecholamine Challenge
Authors: Felix A Trogisch, Franziska Koser, Andreas Jungmann, Oliver J Müller, Markus Hecker, Oliver Drews
Journal: Circulation Research (2018)

Introduction: Cardiac remodeling is associated with a dynamic regulation of the ubiquitin-proteasome system. Our previous studies revealed cardiac induction of the non-essential proteasome subunit low molecular mass peptide 2 (Lmp2) as an early feature of beta-adrenoreceptor overstimulation, as present in chronic human heart disease. However, the impact of Lmp2 upregulation on the progress of cardiac remodeling has not been characterized in detail so far. Objective: Aim of the study was to monitor the contribution of Lmp2 to cardiac remodeling in a mouse model of beta-adrenoceptor overstimulation. Methods &amp; Results: Unchallenged adult mice congenitally lacking Lmp2 (KO) showed no cardiac abnormality including systolic and diastolic function or morphology. After 7 days of continuous isoproterenol administration (30 mg/kg/d using subcutaneous osmotic mini-pumps), both fractional shortening and active diastolic filling of the left ventricle were significantly reduced (by 32%) in Lmp2 KO mice as compared to wildtype littermates (p&lt;0.01, n≥9). Cardiomyocyte-specific adeno-associated virus serotype 9-mediated transfer of the gene encoding Lmp2 rescued cardiac function in Lmp2 KO mice, suggesting that Lmp2 deficiency in cardiomyocytes causes this cardiac phenotype. The decline of systolic and diastolic function was accompanied by increased gain in heart weight to body weight ratio as well as wall thickness, ruling out dilatation of the left ventricle. On cellular level, cardiomyocyte cross-sectional area was markedly augmented (+52% vs. +32% Lmp2 KO vs. WT) as compared to corresponding sham-treated mice (p&lt;0.05, n=3) without altering cardiomyocyte length. To exclude an impact of the remodeling process per se on measuring ventricular function, cardiac contractility was directly assessed by using speckle-tracking analyses. Interestingly, peak circumferential strain and strain rate were both markedly decreased in Lmp2 KO mice following isoproterenol treatment as compared to WT mice. Conclusions: Cardiac, presumably cardiomyocyte induction of Lmp2 seems to be protective in the course of cardiac hypertrophy while lack of Lmp2 exacerbates cardiac remodeling, causing a decline of cardiac function despite increased ventricular muscle mass.
PTU-091 Grading oesophageal varices in clinical practice: an inter-rater reliability study using high resolution endoscopy recordings
Authors: W Fateen, SS Sami, K Ragunath, EA Wilkes, MW James, J Ortiz-Ferna cacute, ndez-Sordo, JR White, A Khanna, M Coletta, S Samuel, GP Aithal, IN Guha
Journal: Gut (2017)

Introduction  Variceal size is a major predictor of the risk of bleeding in patients with liver cirrhosis. Guidelines from the American Association for the Study of the Liver (AASLD) recommend the use of a simplified system (small vs large) for grading of oesophageal varices (OV), but data on the reliability of this system compared to the conventional 3- grade classification remains lacking. We aimed to assess inter-rater reliability of these two widely used grading systems for OV.  Method  High-resolution endoscopy recordings of 108 patients (n=8 training cohort and n=100 evaluation cohort) with chronic liver disease were prospectively collected using standardised criteria. Nine Gastroenterologists of variable experience performed independent evaluations of the videos in a random order. The cases were scored according to the presence or absence of OV. If OV were present they were scored using a 2-grade system (small and large) as well as a 3-grade system (small, medium and large). Overall agreement was analysed using intraclass correlation coefficient or kappa statistic as required.  Results  Agreement on the presence or absence of varices was good (k=0.6, p  Conclusion  Observers had a good to substantial level of agreement using 2 different scoring systems of OV. We conclude that the simpler 2-grade system recommended by AASLD appears to be equivalent to the 3-grade system in terms of inter-observer agreement. This is the first study to support its use in clinical practice.  Disclosure of Interest  None Declared
Outcomes after Third Party, Viral-Specific, Cytotoxic Lymphocytes for Immunosuppression- and Epstein-Barr Virus-Associated Lymphoproliferative Disease
Authors: Sajida Kazi, Abhinav Mathur, Gwen M. Wilkie, Kirsty Cheal, Richard Battle, Neil McGowan, Emily Jane Hargreaves, David Turner, John D.M. Campbell, Marc Turner, Mark A Vickers
Journal: Blood (2018)
ANGIOTENSIN-CONVERTING ENZYME INHIBITORS/ANGIOTENSIN RECEPTOR BLOCKERS IN ELDERLY PATIENTS WITH LEFT VENTRICULAR SYSTOLIC DYSFUNCTION AND ADVANCED CHRONIC KIDNEY DISEASE: DANGER OR BENEFIT?
Authors: Juan Martinez Milla, Marcelino Cortes, Ana Lucia Rivero Monteagudo, Marta Lopez Castillo, Ana Devesa, Mikel Taibo Urquia, Maria Luisa Martin Mariscal, Sem Briongos-Figuero, Juan Antonio Franco Pelaez, José Tunon
Journal: Journal of the American College of Cardiology (2019)