Brief Commentary: Marijuana and Cardiovascular Disease—What Should We Tell Patients?
Authors: Tina M. Kaufman, Sergio Fazio, Michael D. Shapiro
Journal: Annals of Internal Medicine (2019)

Ideas and Opinions15 January 2019Brief Commentary: Marijuana and Cardiovascular Disease—What Should We Tell Patients?Tina M. Kaufman, PhD, PA-C, Sergio Fazio, MD, PhD, and Michael D. Shapiro, DOTina M. Kaufman, PhD, PA-CCenter for Preventive Cardiology, Knight Cardiovascular Institute, Oregon Health & Science University, Portland, Oregon (T.M.K., S.F., M.D.S.)Search for more papers by this author, Sergio Fazio, MD, PhDCenter for Preventive Cardiology, Knight Cardiovascular Institute, Oregon Health & Science University, Portland, Oregon (T.M.K., S.F., M.D.S.)Search for more papers by this author, and Michael D. Shapiro, DOCenter for Preventive Cardiology, Knight Cardiovascular Institute, Oregon Health & Science University, Portland, Oregon (T.M.K., S.F., M.D.S.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/M18-3009 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Editors' Note: This commentary was selected for publication from among 100 submitted manuscripts in response to a call for readers' perspectives on prescribing or recommending marijuana.Marijuana was originally introduced to the United States as a medicinal product in the mid-1800s. It has since been sanctioned (1937), then made illegal (1970), and has now come full circle back to medicine. As of March 2018, a total of 30 states plus the District of Columbia have adopted legislation that broadly legalizes marijuana in some form—8 states plus the District of Columbia have implemented the most expansive laws that permit recreational use ...References1. Governing. State marijuana laws in 2018 map. 2018. Accessed at www.governing.com/gov-data/state-marijuana-laws-map-medical-recreational.html on 7 November 2018. Google Scholar2. Wu TC, Tashkin DP, Djahed B, Rose JE. Pulmonary hazards of smoking marijuana as compared with tobacco. N Engl J Med. 1988;318:347-51. [PMID: 3340105] CrossrefMedlineGoogle Scholar3. Thomas G, Kloner RA, Rezkalla S. Adverse cardiovascular, cerebrovascular, and peripheral vascular effects of marijuana inhalation: what cardiologists need to know. Am J Cardiol. 2014;113:187-90. [PMID: 24176069] doi:10.1016/j.amjcard.2013.09.042 CrossrefMedlineGoogle Scholar4. Ravi D, Ghasemiesfe M, Korenstein D, Cascino T, Keyhani S. Associations between marijuana use and cardiovascular risk factors and outcomes: a systematic review. Ann Intern Med. 2018;168:187-94. [PMID: 29357394]. doi:10.7326/M17-1548 LinkGoogle Scholar5. Azofeifa A, Mattson ME, Schauer G, McAfee T, Grant A, Lyerla R. National estimates of marijuana use and related indicators—National Survey on Drug Use and Health, United States, 2002–2014. MMWR Surveill Summ. 2016;65:1-25. doi:10.15585/mmwr.ss6511a1 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Center for Preventive Cardiology, Knight Cardiovascular Institute, Oregon Health & Science University, Portland, Oregon (T.M.K., S.F., M.D.S.)Grant Support: Dr. Shapiro is supported by grant K12 HD043488 from the National Institutes of Health.Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M18-3009.Corresponding Author: Michael D. Shapiro, DO, Oregon Health & Science University, 3181 S.W. Sam Jackson Park Road, Portland, OR 97239; e-mail, [email protected]edu.Current Author Addresses: Drs. Kaufman, Fazio, and Shapiro: Oregon Health & Science University, 3181 S.W. Sam Jackson Park Road, Portland, OR 97239.Author Contributions: Conception and design: T.M. Kaufman, S. Fazio, M.D. Shapiro.Analysis and interpretation of the data: T.M. Kaufman.Drafting of the article: T.M. Kaufman, S. Fazio.Critical revision of the article for important intellectual content: T.M. Kaufman, S. Fazio, M.D. Shapiro.Final approval of the article: S. Fazio, M.D. Shapiro.Collection and assembly of data: T.M. Kaufman.This article was published at Annals.org on 8 January 2019. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoBrief Commentary: Advocating for Blunt Policy Jan K. Carney Brief Commentary: Marijuana Use During Gestation and Lactation—Harmful Until Proved Safe Eli Y. Adashi Brief Commentary: Treating Pain—The Cannabis Conundrum Chester B. 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Clauw Metrics Cited byThe Coronary Artery Risk Development in Young Adults (CARDIA) StudyCannabis Use is Associated with Prevalent Coronary Artery DiseaseArrhythmic Effects of Cannabis in Ischemic Heart DiseaseAssociation between marijuana use and electrocardiographic abnormalities by middle age: the Coronary Artery Risk Development in Young Adults (CARDIA) studyThe positive and negative cardiovascular effects of cannabisMarijuana Use in Patients With Cardiovascular DiseaseRecommending marijuana use: Violation of the Hippocratic aphorism of “do good or do no harm” 15 January 2019Volume 170, Issue 2Page: 119-120KeywordsAddictionCohort studiesDisclosureHealth care providersMarijuanaMyalgiaOintmentsOxygenSafetySympathetic nervous system ePublished: 8 January 2019 Issue Published: 15 January 2019 Copyright & PermissionsCopyright © 2019 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...