tbuckley/cabot-search huggingface dataset:
COMPARISON OF ENDOCLOT, A NOVEL POLYSACCHARIDE HAEMOSTATIC AGENT, AND ENDOSCOPIC CLIPPING IN THE PREVENTION OF POST POLYPECTOMY HAEMORRHAGE - A RETROSPECTIVE COHORT STUDY
Authors: D Subhaharan, A Lyon, K Tang, S John
Journal: Endoscopy (2020)

Aims Post polypectomy haemorrhage (PPH) can occur in 6-10% of cases of colonic polyps > 20mm. Risk factors suggested include lesion size, proximal location and use of anticoagulants or antiplatelets. Topical haemostats and clips could be used for prevention. Our study compares their use for resections > 20mm.
Wegener Granulomatosis and Trimethoprim-Sulfamethoxazole
Authors: Burton C. West, John R. Todd, John W. King
Journal: Annals of Internal Medicine (2020)

Abstract Wegener granulomatosis was diagnosed in a 42-year-old woman in 1965. Although a regimen of azathioprine and prednisone was helpful, the disease progressed. Cyclophosphamide was added to th...
Skin‐infiltrating basophils promote atopic dermatitis‐like inflammation via IL‐4 production in mice
Authors: Yoshinori Yamanishi, Kotone Mogi, Kazufusa Takahashi, Kensuke Miyake, Soichiro Yoshikawa, Hajime Karasuyama
Journal: Allergy (2020)

Patients with atopic dermatitis (AD) often show the infiltration of basophils in the affected skin. Because basophils represent only a minor fraction among cellular infiltrates in the skin lesion, the functional significance of skin-infiltrating basophils in AD pathogenesis remains ill-defined. In this study, we aimed to clarify the role of basophils and their effector molecules triggering skin inflammation in oxazolone (OX)-induced murine model of AD.A panel of mouse strains were sensitized and repeatedly challenged with topical applications of OX to induce AD-like skin inflammation. Both local and systemic Th2 immune responses were analyzed.Basophils progressively accumulated in the skin lesion but barely in draining lymph nodes (LNs). When basophils were depleted during the elicitation phase, skin inflammation was ameliorated while Th2 cell differentiation in draining LNs remained intact. The expression of IL-4 was highly upregulated in the affected skin, and basophils turned out to be the major producers of IL-4 among cellular infiltrates, suggesting the involvement of basophil-derived IL-4 in the Th2 skin inflammation. Indeed, basophil-specific IL-4-deficient mice displayed attenuated skin inflammation with a marked reduction of IL-4 in the skin lesion, even though cutaneous basophil infiltration and serum levels of IgE remained intact.Skin-infiltrating basophils promoted OX-induced AD-like skin inflammation through their local production of IL-4, rather than the induction of Th2 cell differentiation in draining LNs. This study suggests that the selective targeting of basophils could be a beneficial strategy in the treatment of a certain type of AD.
THE ERCP-RELATED LAWSUIT: THE DECLINE OF PANCREATITIS AND THE RISE OF INFECTIONS
Authors: G Balan, V Sandru, C Sfarti, G Constantinescu, A Trifan
Journal: Endoscopy (2020)

Aims The aim of our research is to determine the main causes for the ERCP-related lawsuits and to describe possible time trends regarding the causes for professional liability and medical litigation.
PORTAL HYPERTENSION CHOLANGIOPATHY. A RARE CASE DIAGNOSED BY CHOLANGIOSCOPY
Authors: A Fernández López, S Alonso Lorenzo, E Barbeito Castro, M Gómez Rivas, AG Gómez, L López Rosés
Journal: Endoscopy (2020)

64-year-old male follow up of alcoholic liver cirrhosis with portal hypertension that in abdominal ultrasound of hepatocarcinoma screening, was evidenced dilatation of the intrahepatic bile duct.
Favorable Anakinra Responses in Severe Covid-19 Patients with Secondary Hemophagocytic Lymphohistiocytosis
Authors: George Dimopoulos, Quirijn de Mast, Nikolaos Markou, Maria Theodorakopoulou, Apostolos Komnos, Maria Mouktaroudi, Mihai G. Netea, Themistoklis Spyridopoulos, Rebecca J. Verheggen, Jacobien Hoogerwerf, Alexandra Lachana, Frank L. van de Veerdonk, Evangelos J. Giamarellos-Bourboulis
Journal: Cell Host & Microbe (2020)
MODIFIED TECHNIQUE THROUGH OVERTUBE FOR ENDOSCOPIC VACUUM-ASSISTED CLOSURE IN PATIENTS WITH ESOPHAGEAL ANASTOMOTIC LEAK
Authors: SM Park, KB Kim
Journal: Endoscopy (2020)

Aims Endoscopic vacuum-assisted closure (E-VAC) therapy is safe and effective for esophageal anastomotic leaks. However, repetitive exchange of sponge tube is technically demanding. We designed modified through overtube technique to make safe and comfortable for both endoscopists and patients.
A DCNN-BASED SYSTEM FOR CLASSIFICATION OF GASTRITIS LESIONS
Authors: H Yu, Y Zhu, S Hu
Journal: Endoscopy (2020)

Aims Endoscopic morphological diagnosis of gastritis plays a crucial role in the gastritis diagnosis. Endoscopists tend to be subjective when classifying gastritis images, and different physicians will have certain differences in the judgment of the same image. In order to avoid the influence of subjectivity on the endoscopists’ diagnosis, we used deep learning to classify endoscopic gastritis images more objectively and accurately.
THE ON-DEMAND NUMBER OF NECROSECTOMY SESSIONS DURING LUMEN APPOSING METAL STENTS DRAINAGE IN WALLED-OFF PANCREATIC NECROSIS CANNOT BE PREDICTED
Authors: A Seicean, O Mosteanu, C Pojoga, M Gheorghiu, LA Lucaciu, A Bartos, N Al Hajjar, R Seicean
Journal: Endoscopy (2020)

Aims To assess the possible prediction for the need of necrosectomy according to the amount of necrosis inside the WOPN assessed during endosonography (EUS).
THE ROLE OF ENDOSCOPIC RETROGRADE CHOLANGIOPANCREOTOGRAPHY AND CHOLANGIOSCOPY IN BILIARY OBSTRUCTION SECONDARY TO HYDATID CYST
Authors: N Elamin, L Dwyer, R Saleem, R Sturgess
Journal: Endoscopy (2020)

A 45 years old female presented with acute severe cholangitis. She had an occupational history of agricultural work in Eastern European Littoral area. Gallstones disease was suspected but radiological imaging demonstrated well-defined encapsulated cystic lesions within the liver with gross biliary dilatation suggesting active Hydatid disease. The patient was commenced on albendazole but the symptoms of biliary obstruction did not improve. The patient underwent endoscopic retrograde cholangiopancreatography (ERCP) and cholangioscopy. The video attached demonstrates the findings in the ERCP and cholangioscopy.
Benefits and Harms of Once-Weekly Glucagon-like Peptide-1 Receptor Agonist Treatments
Authors: Francesco Zaccardi, Zin Zin Htike, David R. Webb, Kamlesh Khunti, Melanie J. Davies
Journal: Annals of Internal Medicine (2015)

This network meta-analysis of 34 randomized trials involving 21 126 participants examines benefits and harms of once-weekly glucagon-like peptide-1 receptor agonists in adults with type 2 diabetes.
The Effects of Tissue Plasminogen Activator, Streptokinase, or Both on Coronary-Artery Patency, Ventricular Function, and Survival after Acute Myocardial Infarction
Authors: The GUSTO Angiographic Investigators
Journal: New England Journal of Medicine (1993)

Although it is known that thrombolytic therapy improves survival after acute myocardial infarction, it has been debated whether the speed with which coronary-artery patency is restored after the initiation of therapy further affects outcome.
ESD FOR REMOVAL OF EARLY CANCER OF THE PHARYNX
Authors: K Shishin, I Nedoluzhko, E Chernikova, I Kanischev, L Shumkina, N Kurushkina
Journal: Endoscopy (2020)

A 68 year old patient came to our hospital to perform EGDS as planned. According to EGDS on the back wall of the oropharynx epithelial neoplasm is determined by the size of 1 cm in diameter. Biopsy performed.
Arginine Depletion Therapy with ADI-PEG20 Limits Tumor Growth in Argininosuccinate Synthase–Deficient Ovarian Cancer, Including Small-Cell Carcinoma of the Ovary, Hypercalcemic Type
Authors: Jennifer X. Ji, Dawn R. Cochrane, Basile Tessier-Cloutier, Shary Yutin Chen, Germain Ho, Khyatiben V. Pathak, Isabel N. Alcazar, David Farnell, Samuel Leung, Angela Cheng, Christine Chow, Shane Colborne, Gian Luca Negri, Friedrich Kommoss, Anthony Karnezis, Gregg B. Morin, Jessica N. McAlpine, C. Blake Gilks, Bernard E. Weissman, Jeffrey M. Trent, Lynn Hoang, Patrick Pirrotte, Yemin Wang, David G. Huntsman
Journal: Clinical Cancer Research (2020)

Many rare ovarian cancer subtypes, such as small-cell carcinoma of the ovary, hypercalcemic type (SCCOHT), have poor prognosis due to their aggressive nature and resistance to standard platinum- and taxane-based chemotherapy. The development of effective therapeutics has been hindered by the rarity of such tumors. We sought to identify targetable vulnerabilities in rare ovarian cancer subtypes.We compared the global proteomic landscape of six cases each of endometrioid ovarian cancer (ENOC), clear cell ovarian cancer (CCOC), and SCCOHT to the most common subtype, high-grade serous ovarian cancer (HGSC), to identify potential therapeutic targets. IHC of tissue microarrays was used as validation of arginosuccinate synthase (ASS1) deficiency. The efficacy of arginine-depriving therapeutic ADI-PEG20 was assessed in vitro using cell lines and patient-derived xenograft mouse models representing SCCOHT.Global proteomic analysis identified low ASS1 expression in ENOC, CCOC, and SCCOHT compared with HGSC. Low ASS1 levels were validated through IHC in large patient cohorts. The lowest levels of ASS1 were observed in SCCOHT, where ASS1 was absent in 12 of 31 cases, and expressed in less than 5% of the tumor cells in 9 of 31 cases. ASS1-deficient ovarian cancer cells were sensitive to ADI-PEG20 treatment regardless of subtype in vitro. Furthermore, in two cell line mouse xenograft models and one patient-derived mouse xenograft model of SCCOHT, once-a-week treatment with ADI-PEG20 (30 mg/kg and 15 mg/kg) inhibited tumor growth in vivo.Preclinical in vitro and in vivo studies identified ADI-PEG20 as a potential therapy for patients with rare ovarian cancers, including SCCOHT.
THROUGH-THE-SCOPE ESOPHAGEAL STENT FOR THE RELIEF OF MALIGNANT DYSPHAGIA: RESULTS OF A MULTICENTRIC STUDY (WITH VIDEO)
Authors: B Mangiavillano, F Auriemma, M Bianchetti, N Mantovani, S Pilati, D Reggio, D Barletti, E Forcignano, G Pentassuglia, A Arezzo, E Cavargini, C Fabbri, L De Luca, R Conigliaro, A Repici
Journal: Endoscopy (2020)

Aims Esophageal cancer is the sixth most common cancer worldwide. In presence of non-surgical candidate presenting dysphagia, the placement of a self-expandable metal stent (SEMS) represents a safe and effective palliative There are no data in literature about the use of the new Taewoong through-the-scope (TTS) esophageal stent (ES) placed for malignant dysphagia. The aim of our study is to evaluate technical success and clinical efficacy of the new Taewoong ES-TTS esophageal stent in this group of patients.
Abstract 10572: Lower Heart Rates Are Associated With Elevated Brain Natriuretic Peptide Levels and Incident Atrial Fibrillation
Authors: Markus Meyer, Paul D Ziegler, Jodi L Koehler
Journal: Circulation (2018)

Introduction: Lower heart rates (HR) prolong left ventricular (LV) filling time which may result in higher LV filling pressures and wall stress. Consequently, lower HR could be associated with high...
´FORGOTTEN´ RETROPERITONEAL DOUBLE-PIGTAIL PLASTIC STENT CAUSING COLONIC FISTULIZATION AND ANEMIA 6 YEARS LATER: ENDOSCOPIC REMOVAL
Authors: A Terán, M Moris, CD Pozo, M Pascual, JC Rodriguez Duque, C Rivas, MJL Arias, LM Ramos, J Crespo, FJ Jimenez Perez
Journal: Endoscopy (2020)

A 72-years-old man suffering from iron deficiency anemia who had undergone an EUS-guided transgastric pseudocyst drainage with double-pigtail plastic stents 6 years earlier. During the procedure, one stent migrated into the pseudocyst and decisition was to leave it in place. Patient remained asypmtomatic for 6 years, then he developed anemia. Colonoscopy found the stent penetrating into the descending colon. After a CT-scan showing no complications, a new colonoscopy was performed for stent removal and wall defect closure with Ovesco clip.
Water Intoxication in Man After Cyclophosphamide Therapy
Authors: Ralph A. DeFRONZO, Hayden Braine, O. Michael Colvin, Paul J. Davis
Journal: Annals of Internal Medicine (2020)

Abstract Cyclophosphamide therapy in doses greater than 50 mg/kg body weight has resulted in frank impairment of water excretion in 17 of 19 normally hydrated patients with cancer. Clinically, thes...
Survival in Patients with Primary Pulmonary Hypertension
Authors: Gilbert E. D'Alonzo, Robyn J. Barst, Stephen M. Ayres, Edward H. Bergofsky, Bruce H. Brundage, Katherine M. Detre, Alfred P. Fishman, Roberta M. Goldring, Berton M. Groves, Janet T. Kernis, Paul S. Levy, Giuseppe G. Pietra, Lynne M. Reid, John T. Reeves, Stuart Rich, Carol E. Vreim, George W. Williams, Margaret Wu
Journal: Annals of Internal Medicine (2020)

▪ Objective: To characterize mortality in persons diagnosed with primary pulmonary hypertension and to investigate factors associated with survival. ▪ Design: Registry with prospective follow-up. ▪...
DEVELOPMENT OF ENDOSCOPIC SCORING SYSTEM TO PREDICT RISK OF INTESTINAL TYPE GASTRIC CANCER: PRELIMINARY PROSPECTIVE STUDY
Authors: HK Na, KD Choi, YS Park, GH Kim, JY Ahn, JH Lee, KW Jung, DH Kim, HJ Song, GH Lee, H-Y Jung
Journal: Endoscopy (2020)

Aims We aimed to develop endoscopic scoring system to evaluate atrophic gastritis and intestinal metaplasia using narrowing band imaging (NBI) and magnification view and to compare endoscopic scores with Operative link for gastritis assessment (OLGA) and Operative link for gastric intestinal metaplasia assessment (OLGIM).
OFF-LABEL ENDOSCOPIC ULTRASOUND (EUS) APPLICATIONS OF ELECTROCAUTERY-ENHANCED LUMEN APPOSING METAL STENT (ECE-LAMS) IN GASTROINTESTINAL ENDOSCOPY (GIE): A SINGLE CENTER CASE SERIES EXPERIENCE
Authors: M Amata, I Tarantino, D Ligresti, L Barresi, A Granata, M Traina
Journal: Endoscopy (2020)

Aims Advancements in endoscopic equipmentaccessories and technical improvements of endoscopists have permitted a worldwide expansion of EUS-guided procedures with progressive rise of its indications in gastrointestinal (GI) diseases, stole from more invasive interventions including surgery and intervention radiology. Recently, ECE-LAMS (Electrocautery enhanced delivery system - Lumen apposing metal stent) allowed a single-step exchange-free apposition of two hollow cavity, creating endoscopic anastomosis or transluminal drainages [1-3].
SEVERE DEFERRED BLEEDING AFTER POEM, ENDOSCOPIC RESOLUTION OF THE CASE
Authors: P Roson, F Cano, L Vazquez, F Melgarejo, A Garcia, J Calle, E Albeniz
Journal: Endoscopy (2020)

Minor complications in POEM are the most frequent and mainly the ones related to gas, Capoperitoneum/mediastinal, in 10% of cases. Deferred bleeding in 0.8%.
AUDIT OF ESD FOR COLORECTAL MUCOSAL LESIONS AT A SINGLE CENTER FROM A REGION NON ENDEMIC FOR COLORECTAL CANCER – CLINICAL OUTCOMES AND LEARNING CURVE
Authors: S Dharamsi, A Bapaye, P Dashatwar
Journal: Endoscopy (2020)

Aims Colorectal ESD is technically challenging and has significant learning curve. Study reports results of in-house audit of ESD’s for colorectal mucosal lesions at single center and analyses learning curve for ESD atcenter in region non endemic for colorectal cancer.
Remodeling of light and dark zone follicular dendritic cells governs germinal center responses
Authors: Natalia B. Pikor, Urs Mörbe, Mechthild Lütge, Cristina Gil-Cruz, Christian Perez-Shibayama, Mario Novkovic, Hung-Wei Cheng, César Nombela-Arrieta, Takashi Nagasawa, Michelle A. Linterman, Lucas Onder, Burkhard Ludewig
Journal: Nature Immunology (2020)
COVID-19–associated Pulmonary Aspergillosis
Authors: Andreas L. E. van Arkel, Tom A. Rijpstra, Huub N. A. Belderbos, Peter van Wijngaarden, Paul E. Verweij, Robbert G. Bentvelsen
Journal: American Journal of Respiratory and Critical Care Medicine (2020)

of intermittent iNO therapy made this approach reasonable for our patient.This patient was remotely managed by clinicians and was more amenable (as a physician herself) to self-monitoring and self-directed therapy than the ordinary patient would be.This is not a typical case, and although the clinical improvement she experienced may not be wholly generalizable, her care represents a first step toward support for outpatient use of iNO to treat exacerbation of PH symptoms due to COVID-19.This approach should not replace best clinical practices when patients present with more substantial symptoms and progressive worsening.Although this case may serve as a proof of concept, it does not prove the utility of iNO for treating respiratory manifestations of COVID-19.Well-designed clinical trials are needed to evaluate the effectiveness of iNO in the setting of COVID-19.If this approach is demonstrated to be effective, outpatient iNO may serve to not only improve clinical outcomes but also reduce the strain on inpatient resources in the current pandemic.
A SYSTEMATIC REVIEW AND META-ANALYSIS OF ENDOSCOPIC AND SURGICAL RESECTION FOR AMPULLARY LESIONS
Authors: C Heise, EA Ali, F Auriemma, A Gulla, S Regner, S Gaujoux, M Hollenbach
Journal: Endoscopy (2020)

Aims Ampullary lesions (ALs) can be treated by endoscopic-ampullectomy (EA), surgical-ampullectomy (SA) or pancreaticoduodenectomy (PD). EA reveals high risk of incomplete resection and surgical interventions lead to substantial morbidity and mortality. To date, there are no prospective comparative trials. We performed a systematic review and meta-analysis to analyze complete resection (R0), adverse events (AEs) and recurrence between EA, SA and PD.
PKG1α Cysteine-42 Redox State Controls mTORC1 Activation in Pathological Cardiac Hypertrophy
Authors: Christian U. Oeing, Taishi Nakamura, Shi Pan, Sumita Mishra, Brittany L. Dunkerly-Eyring, Kristen M. Kokkonen-Simon, Brian L. Lin, Anna Chen, Guangshuo Zhu, Djahida Bedja, Dong Ik. Lee, David A. Kass, Mark J. Ranek
Journal: Circulation Research (2020)

Stimulated PKG1α (protein kinase G-1α) phosphorylates TSC2 (tuberous sclerosis complex 2) at serine 1365, potently suppressing mTORC1 (mechanistic [mammalian] target of rapamycin complex 1) activation by neurohormonal and hemodynamic stress. This reduces pathological hypertrophy and dysfunction and increases autophagy. PKG1α oxidation at cysteine-42 is also induced by these stressors, which blunts its cardioprotective effects.
Import of Aspartate and Malate by DcuABC Drives H2/Fumarate Respiration to Promote Initial Salmonella Gut-Lumen Colonization in Mice
Authors: Bidong D. Nguyen, Miguelangel Cuenca V., Johannes Hartl, Ersin Gül, Rebekka Bauer, Susanne Meile, Joel Rüthi, Céline Margot, Laura Heeb, Franziska Besser, Pau Pérez Escriva, Céline Fetz, Markus Furter, Leanid Laganenka, Philipp Keller, Lea Fuchs, Matthias Christen, Steffen Porwollik, Michael McClelland, Julia A. Vorholt, Uwe Sauer, Shinichi Sunagawa, Beat Christen, Wolf-Dietrich Hardt
Journal: Cell Host & Microbe (2020)
LONG-TERM OUTCOME OF SALVAGE ENDOSCOPIC RESECTION AFTER DEFINITIVE CHEMORADIOTHERAPY FOR OESOPHAGEAL CANCER: A WESTERN EXPERIENCE
Authors: A Al-Kaabi, RHA Verhoeven, PH Deprez, S Seewald, M Giovannini, B Braden, EJ Schoon, F Berr, A Lemmers, J Hoare, P Bhandari, RS van der Post, PD Siersema
Journal: Endoscopy (2020)

Aims Definitive chemoradiotherapy (dCRT) is increasingly used as non-surgical treatment for oesophageal cancer. Local failure after dCRT at the primary site is common and remains a major challenge. In Japanese series, salvage endoscopic resection (ER) has emerged as promising treatment modality for superficial residual/recurrent lesions after dCRT. Comparable data from outside Japan are scarce. The primary aim was to evaluate the safety and long-term efficacy of salvage ER in a Western case series.
CONSENTING FOR ENDOSCOPIC PROCEDURES - HOW CAN WE OPTIMISE THE PROCESS?
Authors: R Cama, R Patel, L Carvalho, A Cross, K Besherdas
Journal: Endoscopy (2020)

Aims The British Society of Gastroenterology (BSG) consent guidelines advise that good consenting practice is an important part of the Global Rating Scale (GRS) assessment of UK endoscopic units. The high volume of outpatients undergoing elective endoscopic procedures can lead to insufficient consent documentation. We aimed to review our consent process and identify factors where it could be optimised.
The COVID-19 Pandemic and Acute Aortic Dissections in New York
Authors: Ismail El-Hamamsy, Derek R. Brinster, Joseph J. DeRose, Leonard N. Girardi, Kazuhiro Hisamoto, Mohammed N. Imam, Shinobu Itagaki, Paul A. Kurlansky, Christopher Lau, Samantha Nemeth, Mathew Williams, Benjamin A. Youdelman, Hiroo Takayama
Journal: Journal of the American College of Cardiology (2020)
IMPACT OF ENHANCED INSTRUCTIONS FOR BOWEL PREPARATION ON THE QUALITY OF BOWEL CLEANSING FOR PATIENTS UNDERGOING OUTPATIENT COLONOSCOPY
Authors: D Penz, C Schweitzer, A Ferlitsch
Journal: Endoscopy (2020)

Aims The ESGE recommends the use of enhanced instructions for bowel preparation. Limited literature exists regarding educational interventions at the daily routine. Therefore, aim of this study was to assess the effect of enhanced instructions in an extra appointment for patients undergoing outpatient colonoscopy.
UPPER EUS ENDOSCOPIST DIRECTED PROPOFOL SEDATION: RISKS FACTORS OF DESATURATION
Authors: S Bazaga, R Ballester, A Vargas, M Alburquerque, N Zaragoza, G Torres, M Pechkova, JM Miñana, JM Reñe, F Gonzalez-Huix
Journal: Endoscopy (2020)

Aims Describe risk-related factors of desaturation during EUS sedation taken into account the clinical and facial characteristics.
COVID-19 and cancer: do we really know what we think we know?
Authors: Andrew G. Robinson, Bishal Gyawali, Gerald Evans
Journal: Nature Reviews Clinical Oncology (2020)

Early published data on COVID-19 in patients with cancer are being referenced in clinical guidelines, despite methodological flaws that limit the quality of much of this evidence. In the next phase of research in this area, we argue that the quality of observational evidence should be prioritized over speed of publication.
Abstract 12456: Effective Hemoglobin Level for the Prevention of All-Cause Mortality is Different Between Male and Female Patients With Heart Failure With Preserved Ejection Fraction
Authors: Keisuke Okuno, Yoshiro Naito, Masanori Asakura, Masataka Sugahara, Tomotaka Ando, Toshiyuki Nagai, Yoshihiko Saito, Tsutomu Yoshikawa, Tohru Masuyama, Toshihisa Anzai
Journal: Circulation (2018)

Introduction: The prevalence of anemia is higher in heart failure with preserved left ventricular ejection fraction (HFpEF) than in heart failure with reduced left ventricular ejection fraction. Ho...
CLINICAL VALIDATION OF BLI ADENOMAS SERRATED INTERNATIONAL CLASSIFICATION (BASIC) FOR RESECT AND DISCARD STRATEGY FOR DIMINUTIVE COLORECTAL POLYPS (BIRD STUDY)
Authors: E Rondonotti, C Hassan, A Andrealli, S Paggi, A Amato, L Scaramella, A Repici, F Radaelli
Journal: Endoscopy (2020)

Aims Blue Light Imaging (BLI) Adenomas Serrated International Classification (BASIC) has been shown to accurately predict histology of ≤10 mm colorectal polyps in an artificial setting with BLI. Study aim: to validate BASIC in a clinical setting by using as reference standard the thresholds recommended by the American Society for Gastrointestinal Endoscopy for resect and discard (R&D) strategy.
PALISADE TECHNIQUE AS AN EFFECTIVE METHOD OF ENDOSCOPIC SUBMUCOSAL DISSECTION FOR COLORECTAL TUMORS GREATER THAN HALF A LUMINAL CIRCUMFERENCE
Authors: Y Suzuki, K Ohata, S Takayanagi, Y Kimoto, M Kurebayashi, T Hirata, R Ishii, T Konishi, K Kanda, R Negishi, M Takita, K Ono, Y Minato, E Sakai, T Muramoto, N Matsuhashi
Journal: Endoscopy (2020)

Aims Although ESD has become the effective therapeutic strategy for colorectal tumors, it still remains challenging to treat large tumors, especially those greater than 50 mm in size, the size that has been reported as an independent risk factor for post-ESD complications. We invented a new technique of ESD called palisade technique, which is effective in dissecting large colorectal tumors. In this study, we investigated the outcomes of colorectal ESD using palisade technique.