THE USE OF THE MERCURIAL SUPPOSITORY AS A DIURETIC
Authors: JAMES  FLEXNER
Journal: Annals of Internal Medicine (1938)

Article1 May 1938THE USE OF THE MERCURIAL SUPPOSITORY AS A DIURETICJAMES FLEXNER, M.D.JAMES FLEXNER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-11-11-1962 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptINTRODUCTIONOrganic mercurial compounds have been recognized as having valuable diuretic properties since 19201and have been used with increasing frequency since the introduction of salyrgan in 1924.2Later mercupurin (novurit), neptal and mercurosal were used. These drugs proved to be of great benefit in the treatment of cardiac edema, of moderate assistance in the management of nephrotic edema, and of lesser therapeutic value in the edema and ascites of hepatic cirrhosis. In addition to the known limitations, the drugs were objectionable because they were mercurials and thus renal irritants. Great care was therefore necessary in controlling their administration to...Bibliography1. SAXLHEILIG PR: Über die diuretische Wirkung von Novasurol und anderen Quecksilberinjektionen, Wien. klin. Wchnschr., 1920, xxxiii, 943. Google Scholar2. BERNHEIM E: Über das neue Quecksilberpräparat Salyrgan als Diuretikum, Therap. d. Gegenw., 1924, 538, 65. Google Scholar3. FLECKSEDER R: Über Anwendungs—und Wirkungsweise der komplexen Quecksilberdiuretika, Ztschr. f. Urol., 1934, xxviii, 32. Google Scholar4. ENGELEPSTEIN KT: Die Quecksilberdiurese, Ergebn. d. inn. Med. u. Kinderheilk., 1931, xl, 187. Google Scholar5. PARKINSONTHOMSON JWA: A mercurial (novurit) suppository as a diuretic for cardiac edema, Lancet, 1936, ccxxx, 16. CrossrefGoogle Scholar6. FULTON MN: Mercurin suppositories as a diuretic in the treatment of edema, New England Jr. Med., 1936, ccxiv, 1092. CrossrefGoogle Scholar7. HERRMANNDECHERD GGM: Further studies on the mechanism of diuresis with especial reference to the action of some newer diuretics, Jr. Lab. and Clin. Med., 1937, xxii, 767. Google Scholar8. ETHRIDGEMYERSFULTON CBDWMN: Modifying effect of various inorganic salts on the diuretic action of salyrgan, Arch. Int. Med., 1936, lvii, 714. CrossrefGoogle Scholar9. DENNIGDILLTALBOTT HDBJH: Bilanzuntersuchung einer Salmiakazidose, Arch. f. exper. Path. u. Pharmakol., 1929, cxliv, 297. CrossrefGoogle Scholar10. KEITH NM: The action and use of diuretics with especial reference to mercurial compounds, Jr. Am. Med. Assoc., 1936, cvii, 2047. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Received for publication December 20, 1937.From the Department of Medicine, New York Post-Graduate Medical School and Hospital, New York, N. Y.†Campbell Products, Inc., manufacturers of mercupurin and mercurin suppositories in this country, assure us that their products are identical with novurit and novurit suppositories. According to their statement, the term "novurit suppository" is misleading because the suppositories contain no theophylline. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byQuecksilberhaltige Diuretica 1 May 1938Volume 11, Issue 11Page: 1962-1972KeywordsAscitesCirrhosisDiureticsDrugsEdemaHospital medicineSuppository Issue Published: 1 May 1938 PDF downloadLoading ...