PARENTERAL SULFAPYRIDINE; THE INTRAVENOUS USE OF SODIUM SULFAPYRIDINE AND A REPORT OF CLINICAL AND LABORATORY OBSERVATIONS ON THE USE OF A GLUCOSE-SULFAPYRIDINE SOLUTION
Authors: Maxwell Finland, Francis C. Lowell, William C. Spring, F. H. Laskey Taylor
Journal: Annals of Internal Medicine (1940)

Article1 January 1940PARENTERAL SULFAPYRIDINE; THE INTRAVENOUS USE OF SODIUM SULFAPYRIDINE AND A REPORT OF CLINICAL AND LABORATORY OBSERVATIONS ON THE USE OF A GLUCOSE-SULFAPYRIDINE SOLUTIONMAXWELL FINLAND, M.D., F.A.C.P., FRANCIS C. LOWELL, M.D., WILLIAM C. SPRING JR., M.D., F. H. LASKEY TAYLOR, Ph.D.MAXWELL FINLAND, M.D., F.A.C.P.Search for more papers by this author, FRANCIS C. LOWELL, M.D.Search for more papers by this author, WILLIAM C. SPRING JR., M.D.Search for more papers by this author, F. H. LASKEY TAYLOR, Ph.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-13-7-1105 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptMarshall and Long1have recently reported observations on the intravenous use of the sodium salt of sulfapyridine2in patients in whom it is desirable to attain high concentrations of sulfapyridine in the blood rapidly and in patients in whom oral therapy results in inadequate concentrations or entails undue discomfort. Since occasions similar to the ones they outlined frequently arise, and since under such conditions the procedure may be of life-saving value, further reports of the use of this compound seem justified. While the clinical findings reported in this paper with respect to sodium sulfapyridine are largely confirmatory, additional data are...References1. MARSHALLLONG EKPH: The intravenous use of sodium sulfapyridine, Jr. Am. Med. Assoc., 1939, cxii, 1672. Google Scholar2. MARSHALLBRATTONLITCHFIELD EKACJT: The toxicity and absorption of 2-sulfanilamidopyridine and its soluble sodium salt, Science, 1938, lxxxviii, 597. CrossrefGoogle Scholar3. TAYLORLOWELLSPRINGFINLAND FHFCWCM: A comparative study of the blood concentrations and urinary excretion after single doses of sulfapyridine and some related compounds administered by various routes, Jr. Clin. Invest., 1940, xix, 201. CrossrefGoogle Scholar4. MARSHALLLITCHFIELD EKJT: Determination of sulfanilamide, Science, 1938, lxxxviii, 85. CrossrefGoogle Scholar5. ANTOPOLROBINSON WH: Urolithiasis and renal pathology after oral administration of 2(sulfanilylamino)-pyridine (sulfapyridine), Proc. Soc. Exper. Biol. and Med., 1939, xl, 428. CrossrefGoogle Scholar6. SOUTHWORTHCOOKE HC: Hematuria, abdominal pain and nitrogen retention associated with sulfapyridine, Jr. Am. Med. Assoc., 1939, cxii, 1820. Google Scholar7. TOOMEY JA: Urinary concretions and sulfapyridine, Jr. Am. Med. Assoc., 1939, cxiii, 250. CrossrefGoogle Scholar8. LONG PH: (correspondence), Lancet, 1939, i, 60. CrossrefGoogle Scholar9. WHITBY L: Chemotherapy of bacterial infections, Lancet, 1938, ii, 1095. CrossrefGoogle Scholar10. GAISFORDEVANSWHITELAW WFGMW: Parenteral therapy with M. & B. 693, Lancet, 1939, ii, 69. CrossrefGoogle Scholar11. BLAKEHAVILAND FGJW: Trans. Assoc. Am. Phys., 1939, liv, 130. Google Scholar12. LOWELLSPRINGFINLAND FCWCM: Bactericidal action of sodium sulfapyridine and of a glucose-sulfapyridine solution in human blood, Jr. Clin. Invest., 1940, xix, 215. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Boston, Massachusetts*Received for publication October 12, 1939.From the Thorndike Memorial Laboratory, Second and Fourth Medical Services (Harvard) Boston City Hospital, and the Department of Medicine, Harvard Medical School, Boston. Nextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe Treatment of Pulmonary Infections with Sulfanilamide, Sulfapyridine, and SulfathiazoleBlood Concentration, Acetylation and Urinary Excretion of Sulfapyridine and Sulfathiazole after Various Sulfapyridine and Sulfathiazole Derivatives Administered by Different Routes1 1 January 1940Volume 13, Issue 7Page: 1105-1120KeywordsAttentionBloodClinical laboratoriesHospital medicineMedical servicesResearch laboratoriesSaltsSodium Issue Published: 1 January 1940 Copyright & PermissionsCopyright, 1940, by The American College of PhysiciansPDF downloadLoading ...