tbuckley/cabot-search huggingface dataset:
509. A Comparison of AAV Strategies Distinguishes Overlapping Vectors for Efficient Systemic Delivery of the 6.2kb Dysferlin Coding Sequence
Authors: William Lostal, Marina Pryadkina, Isabelle Richard
Journal: Molecular Therapy (2015)

Recombinant AAV (rAAV) is currently the best vector for gene delivery into the skeletal muscle. However, the 5-kb packaging size of this virus is a major obstacle for large gene transfer. This past decade, many different strategies were developed to circumvent this issue (concatemerization-splicing, overlapping vectors, hybrid dual or fragmented AAV). Loss of function mutations in the DYSF gene whose coding sequence is 6.2kb lead to progressive muscular dystrophies (LGMD2B: OMIM_253601; MM: OMIM_254130; DMAT: OMIM_606768). In this study, we compared large gene transfer techniques to deliver the DYSF gene into the skeletal muscle. After rAAV8s intramuscular injection into dysferlin deficient mice, we showed that the overlap strategy is the most effective approach to reconstitute a full-length messenger. After systemic administration, the level of dysferlin obtained on different muscles corresponded to 0.5 to 2 fold compared to the normal level. We further demonstrated that the overlapping vector set was efficient to correct the histopathology, resistance to eccentric contractions and whole body force in the dysferlin deficient mice up to one year after injection. Altogether, these data indicate that using overlapping vectors could be a promising approach for a potential clinical treatment of dysferlinopathies.
Abstract 14329: Outcomes After the Comprehensive Stage 2 Procedure
Authors: Clifford L Cua, Patrick I McConnell, James M Meza, Kevin D Hill, Shuaiqi Zhang, Diane Hersey, Tara Karamlou, Jeffrey P Jacobs, Marshall Jacobs, Mark Galantowicz
Journal: Circulation (2017)

Introduction: Comprehensive Stage 2 procedure (CS2) is the second surgical operation for patients with single ventricle physiology that initially underwent the Hybrid Stage 1 procedure. Goal of this study was to describe CS2 outcomes and determine if there were differences between survivors of CS2 (s-CS2) versus non-survivors of CS2 (nons-CS2). Methods: Data from all patients undergoing an index CS2 procedure between 2010 - 2016 from the Society of Thoracic Surgeons (STS) Congenital Heart Surgery Database (STS-CHSD) were evaluated. Pre-operative, operative, and post-operative data were analyzed, stratified by operative mortality (in-hospital, or within 30 days of surgery), with univariate comparisons using a chi-square or Wilcoxon rank sum test or Fisher exact test. Results: Total of 209 patients (49 centers) met inclusion criteria of which 141 patients had the diagnosis of hypoplastic left heart syndrome. Overall operative mortality was 12.4% (26/209). S-CS2 had a lower prevalence of preoperative ECMO us...
Cyclin G1 and TASCC regulate kidney epithelial cell G <sub>2</sub> -M arrest and fibrotic maladaptive repair
Authors: Guillaume Canaud, Craig R. Brooks, Seiji Kishi, Kensei Taguchi, Kenji Nishimura, Sato Magassa, Adam Scott, Li-Li Hsiao, Takaharu Ichimura, Fabiola Terzi, Li Yang, Joseph V. Bonventre
Journal: Science Translational Medicine (2019)

Cyclin G1 regulates G 2 -M arrest in proximal tubular cells, promoting a TASCC-induced secretory phenotype, fibrosis, and kidney disease progression.
Dose-finding and single-arm confirmatory study of definitive chemoradiotherapy (dCRT) with S-1/mitomycin-C (MMC) in patients (pts) with clinical (c) stage II/III squamous cell carcinoma of the anal canal (SCCA): JCOG0903.
Authors: Atsuo Takashima, Yoshinori Ito, Tetsuya Hamaguchi, Junki Mizusawa, Yasuhiro Shimada, Manabu Shiozawa, Takeshi Kodaira, Masayuki Ohue, Makoto Kinouchi, Kohei Murata, Fumihiko Fujita, Masahiko Watanabe, Yoshihiro Moriya, Gen Iinuma, Fumio Ishida, Yoshihisa Saida, Takahisa Matsuda, Hiroshi Katayama, Haruhiko Fukuda, Yukihide Kanemitsu
Journal: Journal of Clinical Oncology (2019)

686 Background: dCRT with 5-FU/MMC is a standard treatment for cStage II/III SCCA. S-1 is an oral fluoropyrimidine and has a greater effect on radiosensitivity. We conducted this trial of dCRT with S-1/MMC to determine the recommended dose (RD) of S-1 in phase I part (P I) and to evaluate the efficacy and safety in phase II part (P II) for cStage II/III SCCA. When the primary endpoint in P II part is proven to be satisfactory, we can regard this combined treatment as the new standard treatment. Methods: Eligibility criteria included histologically proven SCCA, cStage II/III (UICC 6 th ), PS 0-1, and age 20-80 years. dCRT consisted of MMC (10 mg/m 2 on days 1, 29) and S-1 (60 mg/m 2 /d in level 0 and 80 mg/m 2 /d in level 1 on days 1-14, 29-42) with concurrent 3-dimensional RT of 59.4 Gy/33fr. The P I adopted the 3+3 cohort design. The primary endpoint of P II was proportion of 3-year event-free survival (% 3-year-EFS). The sample size was 65 in the P II, with one-sided alpha of 5% and power of 80%, threshold and expected % 3-year EFS as 60% and 75%. Results: From Feb/2010 to Mar/2015, 69 pts (3 in level 0 and 66 [7 in P I and 59 in P II] in level 1) were enrolled. Pts’s backgrounds for level 1 were as follows: M/F, 12/54; Age, median 64 (range 33-80); cStage II/IIIA/IIIB, 29/9/28. Three in level 1 were ineligible and 63 eligible assigned to level 1 were included in efficacy analysis. In the P I, considering the details of DLTs, RD of S-1 was determined as 80 mg/m 2 /d. In the 63 eligible of level 1, %3-year EFS was 65.0% (90% CI 54.1-73.9%). % 3-year OS, PFS, and colostomy-free survival were 87.3% (95% CI 76.2-93.4%), 85.7% (74.3-92.3%), and 76.2% (63.7-84.9%), respectively. The complete response rate was 81% on central review. Among 65 pts receiving level 1 dCRT, common grade 3 or 4 acute toxicities were leukopenia (63.1%), neutropenia (40%), diarrhea (20%), radiation dermatitis (15.4%), and febrile neutropenia (3.1%). Only 6 (9.2%) showed grade 3 late toxicities. No treatment-related deaths were observed. Conclusions: Although dCRT with S-1/MMC showed acceptable toxicities and favorable 3-year survival, this study did not meet its primary endpoint. Clinical trial information: UMIN000003237.
Grading of Neurotoxicity in Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma (r/r DLBCL) Receiving Tisagenlecleucel Treatment in the JULIET Study
Authors: Richard T. Maziarz, Stephen J. Schuster, Vadim V. Romanov, Elisha S. Rusch, James Signorovitch, Solveig G. Ericson, David G. Maloney, Frederick L. Locke
Journal: Blood (2018)
Macrophages, rather than DCs, are responsible for inflammasome activity in the GM-CSF BMDC model
Authors: Ziv Erlich, Inbar Shlomovitz, Liat Edry-Botzer, Hadar Cohen, Daniel Frank, Hanqing Wang, Andrew M. Lew, Kate E. Lawlor, Yifan Zhan, James E. Vince, Motti Gerlic
Journal: Nature Immunology (2019)
Racial/Ethnic Differences in Lung Cancer Incidence in the Multiethnic Cohort Study: An Update
Authors: Daniel O Stram, S Lani Park, Christopher A Haiman, Sharon E Murphy, Yesha Patel, Stephen S Hecht, Loic Le Marchand
Journal: JNCI Journal of the National Cancer Institute (2018)

We previously found that African Americans and Native Hawaiians were at highest lung cancer risk compared with Japanese Americans and Latinos; whites were midway in risk. These differences were more evident at relatively low levels of smoking intensity, fewer than 20 cigarettes per day (CPD), than at higher intensity.We apportioned lung cancer risk into three parts: age-specific background risk (among never smokers), an excess relative risk term for cumulative smoking, and modifiers of the smoking effect: race and years-quit smoking. We also explored the effect of replacing self-reports of CPD with a urinary biomarker-total nicotine equivalents-using data from a urinary biomarker substudy.Total lung cancers increased from 1979 to 4993 compared to earlier analysis. Estimated excess relative risks for lung cancer due to smoking for 50 years at 10 CPD (25 pack-years) ranged from 21.9 (95% CI = 18.0 to 25.8) for Native Hawaiians to 8.0 (95% CI = 6.6 to 9.4) for Latinos over the five groups. The risk from smoking was higher for squamous cell carcinomas and small cell cancers than for adenocarcinomas. Racial differences consistent with earlier patterns were seen for overall cancer and for cancer subtypes. Adjusting for predicted total nicotine equivalents, Japanese Americans no longer exhibit a lower risk, and African Americans are no longer at higher risk, compared to whites. Striking risk differences between Native Hawaiians and Latinos persist.Racial differences in lung cancer risk persist in the Multiethnic Cohort study that are not easily explained by variations in self-reported or urinary biomarker-measured smoking intensities.
Albuminuria, Lung Function Decline, and Risk of Incident Chronic Obstructive Pulmonary Disease. The NHLBI Pooled Cohorts Study
Authors: Elizabeth C. Oelsner, Pallavi P. Balte, Morgan E. Grams, Patricia A. Cassano, David R. Jacobs, R. Graham Barr, Kristin M. Burkart, Ravi Kalhan, Richard Kronmal, Laura R. Loehr, George T. O’Connor, Joseph E. Schwartz, Michael Shlipak, Russell P. Tracy, Michael Y. Tsai, Wendy White, Sachin Yende
Journal: American Journal of Respiratory and Critical Care Medicine (2018)

Chronic lower respiratory diseases (CLRDs), including chronic obstructive pulmonary disease (COPD) and asthma, are the fourth leading cause of death. Prior studies suggest that albuminuria, a biomarker of endothelial injury, is increased in patients with COPD.
Exploratory evaluation of baseline tumor biomarkers and their association with response and survival in patients with previously treated advanced gastric cancer treated with andecaliximab combined with nivolumab versus nivolumab.
Authors: Jean-Philippe Metges, Emon Elboudwarej, David Cunningham, Daniel V.T. Catenacci, Eric Van Cutsem, Zev A. Wainberg, Yafeng Zhang, Scott Turner, Dung Thai, Pankaj Bhargava, Manish A. Shah, Carrie Brachmann
Journal: Journal of Clinical Oncology (2019)

148 Background: Andecaliximab (ADX) is a monoclonal antibody that inhibits matrix metalloproteinase 9 (MMP9). Preclinical studies suggest that MMP9 inhibition relieves immune suppression and promotes T cell infiltration to potentiate checkpoint blockade. In the phase 2 study combining ADX with nivolumab (N) versus N monotherapy (NCT02864381), addition of ADX to N did not improve objective response rate, progression-free survival (PFS), or overall survival (OS). Methods: Archival tumor samples were collected from all patients (n = 141). CD8 and PD-L1 (28-8 DAKO) were assessed by immunohistochemistry. CD8+ cell density was measured in the tumor area. PD-L1 was prospectively scored by a pathologist for tumor cell (TC) and associated immune cell (IC) positivity. IFNg, Teffector (Teff), and activated CD8+ T cell (ActT) gene signatures were assessed by RNA sequencing. Due to a small number of responders, treatment arms were combined to evaluate response. Cox proportional hazards models were used for survival analyses. Nominal p-values are reported. Results: Baseline biomarkers of T cell infiltration and activation did not differentiate responders from non-responders (IFNg, Teff, ActT, CD8+; p &gt; .10). None of the evaluated biomarkers were associated with PFS or OS for all treated patients or per treatment arm (IFNg, Teff, ActT; p &gt; .10), with the exception of CD8+ (PFS HR = .43, p = .02). The majority of baseline samples were positive for IC PD-L1 (&lt; 1%, n = 36; 1-10%, n = 50; &gt; 10-25%, n = 32; &gt; 25%, n = 20) and negative for TC PD-L1 (H = 0, n = 88; H &lt; 1, n = 27; H &gt; 1; n = 27). Comparing ADX/N to N, there was a trend toward longer OS for the PD-L1+ (TC + IC ≥ 1%) population (n = 102, HR = .621, p = .098), the TC H &lt; 1 group (HR = .464, p = .08) and the IC &gt; 10-25% (HR = .466, p = .08). Conclusions: Neither CD8+ cell density nor IFNg, Teff or ActT gene signatures were associated with response or survival to checkpoint blockade. While TC was low, IC intermediate and TC + IC ≥ 1% PD-L1+ groups trended toward better survival for the ADX+N arm, consistent with the hypothesis that ADX potentiates N activity; this did not translate into better outcome. Clinical trial information: NCT02864381.
Extended Survival in CLL Patients Who Discontinued Idelalisib Because of Colitis Correlates with Higher Th17 Levels in Blood and Colon Tissue
Authors: Rukhsana Aslam, Jacqueline C Barrientos, Gerardo Ferrer, Pui Yan Chiu, Kanti R Rai, Nicholas Chiorazzi, Barbara Sherry
Journal: Blood (2018)
Extending Antenatal Pertussis Immunization to Second Trimester or At-Birth Pertussis Immunization of Premature Infants?—Reply
Authors: Nicholas Wood, Terry Nolan, Peter McIntyre
Journal: JAMA Pediatrics (2019)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Pediatrics HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Pediatrics journal
Abstract 18652: Biophysics of Sonoporation for Gene Delivery: Shear Stress Initiates Endothelial Plasma Membrane Perforation and Calcium Signaling
Authors: Brandon Helfield, Xucai Chen, Jianxin Zeng, Simon C Watkins, Flordeliza Villanueva
Journal: Circulation (2016)

Background: Ultrasound (US)-stimulated microbubbles (MBs) are emerging as a target-specific non-viral gene delivery platform for the treatment of vascular disease. The nature of MB-cell interaction...
Colorectal Cancer in Individuals With Familial Adenomatous Polyposis, Based on Analysis of the Danish Polyposis Registry
Authors: John Gásdal Karstensen, Johan Burisch, Hans-Christian Pommergaard, Lisa Aalling, Helle Højen, Niels Jespersen, Palle Nordblad Schmidt, Steffen Bülow
Journal: Clinical Gastroenterology and Hepatology (2019)
Comparison of prasugrel and clopidogrel in patients with non-cardioembolic ischaemic stroke: a phase 3, randomised, non-inferiority trial (PRASTRO-I)
Authors: Akira Ogawa, Kazunori Toyoda, Kazuo Kitagawa, Takanari Kitazono, Takehiko Nagao, Hiroshi Yamagami, Shinichiro Uchiyama, Norio Tanahashi, Masayasu Matsumoto, Kazuo Minematsu, Izumi Nagata, Masakatsu Nishikawa, Shinsuke Nanto, Kenji Abe, Yasuo Ikeda
Journal: The Lancet Neurology (2019)
Use of Active Surveillance or Watchful Waiting for Low-Risk Prostate Cancer and Management Trends Across Risk Groups in the United States, 2010-2015
Authors: Brandon A. Mahal, Santino Butler, Idalid Franco, Daniel E. Spratt, Timothy R. Rebbeck, Anthony V. D’Amico, Paul L. Nguyen
Journal: JAMA (2019)

This cancer epidemiology study uses SEER data to examine US trends in use of active surveillance, watchful waiting, radiotherapy, and surgical management of localized prostate cancer among men with low-, intermediate-, and high-risk disease treated between 2010 and 2015.
Abstract 14670: Human Amniotic Patch Placement During Cardiac Surgery Reduces Post-Operative Atrial Fibrillation
Authors: Prashant Rao, David Schipper, Brian Hallmark, Julia Fisher, Ryan Avery, Katie Marsh, Tia Pilikian, Kitsie Johnson, Dirk Duncker, Dean Billheimer, Ray Runyan, John Konhilas, Zain Khalpey
Journal: Circulation (2017)

Introduction: Atrial fibrillation after cardiac surgery occurs in approximately one third of patients and is associated with increased morbidity and mortality. Inflammation and oxidative stress may...
Multiple Myeloma of Testes and Spermatic Cord on 18F-FDG PET/CT
Authors: Jyothirmayi Velaga, Huang Hian Liang, Sathish Kumar Gopalakrishnan
Journal: Clinical Nuclear Medicine (2019)

Extramedullary multiple myeloma (EM) has negative prognostic implications on the overall survival as well as progression-free survival. Testis is a rare site of EM, which can be a part of diffuse involvement in multiple myeloma or a site of recurrence in patients with remission. We present a case of EM of testes and left spermatic cord in an 80-year-old man who presented with painless progressive enlargement of the scrotum. F-FDG PET/CT revealed tracer avidity of both testes and left spermatic cord. Bilateral radical orchidectomy was subsequently performed, and the diagnosis of multiple myeloma was confirmed on histopathology.
Reply
Authors: Vinod Arora, Rakhi Maiwall, Vijayaraghavan Rajan, Ankur Jindal, Saggere Muralikrishna Shasthry, Guresh Kumar, Priyanka Jain, Shiv Kumar Sarin
Journal: Hepatology (2019)

Potential conflict of interest: Nothing to report. We appreciate Lin et al. for showing interest in our study. We do agree that albumin can synergistically help the vasoconstrictors. However, we would like to point out that the median dosage of albumin of 60 g for initial volume resuscitation was comparable in both the groups. As discussed in the methodology section, 1 g/kg of albumin was used for the initial volume resuscitation followed by 20‐40 g of albumin per day. The dosage of albumin used in our study is in line with prior studies.1 State of acute‐on‐chronic liver failure (ACLF) is believed to be similar to sepsis with increased TNF‐α and nitric oxide and decreased cortisol, leading to circulatory dysfunction, sympathetic overactivity, and vasoconstrictor hyporesponsiveness.2 There is constriction of the vascular smooth muscle constriction with terlipressin and also inhibition of vascular smooth muscle nitric oxide production and K1‐ATP channels resulting in splanchnic vasoconstriction and increasing renal blood flow. As mentioned, there is hyperdynamic state and increased sympathetic discharge, so adding norepinephrine is likely to make little difference.3 Terlipressin compared with noradrenaline causes greater constriction of efferent arterioles and greater increase in fractional excretion of sodium and urine output.3 Despite some negative effect on cardiac output, it promotes renal blood flow to a greater extent compared with noradrenaline. In conclusion, mean dosage of albumin in our study was comparable to previous studies, and terlipressin has a definite advantage in reversal of hepatorenal syndrome acute kidney injury in ACLF compared with noradrenaline.
A Restructured Approach to Diagnosis of Heparin Induced Thrombocytopenia in a Large Tertiary Hospital
Authors: Sriman Swarup, Somedeb Ball, Nimesh Adhikari, Courtney Alice Welch, Jaden Fackrell, Kyaw Zin Thein, Anita Sultan, Khatrina Swarup, Sanjay Awasthi, Lukman Tijani
Journal: Blood (2018)
A High Proportion Of Exacerbation-Prone Patients With Uncontrolled Eosinophilic Asthma Receiving IV Reslizumab Experienced Zero Asthma Exacerbations Through 52 Weeks (wks) Of Treatment
Authors: Margaret Garin, Lisa Hickey, S. Shahzad Mustafa
Journal: Journal of Allergy and Clinical Immunology (2019)
Longer-Term Safety and Efficacy Measures of AR101 Oral Immunotherapy for Peanut Allergy: Results from a Phase 3 Follow-On Study
Authors: Tara F. Carr, Wayne G. Shreffler, Noelle M. Griffin, Karin Rosén, Rezi Zawadzki, John Matthews, Daniel C. Adelman, Stacie M. Jones
Journal: Journal of Allergy and Clinical Immunology (2019)
Abstract 13785: Use of Echocardiography in Referral Outpatients With Chest Pain and Normal Resting Electrocardiograms Seen at Mayo Clinic Rochester
Authors: Damita J Carryer, Raymond J Gibbons, Hongfang Liu, Peter A Brady, John W Askew, David O Hodge, Naser M Ammash, Veronique L Roger, Jon O Ebbert
Journal: Circulation (2017)

Objective: To determine how often unnecessary resting echocardiograms that are “not recommended” by clinical practice guidelines are performed in patients with stable chest pain and normal resting electrocardiograms (ECGs). Patients and Methods: We performed a retrospective search of electronic medical records of all referral outpatients seen at Mayo Clinic Rochester from January 1, 2010, through December 31, 2013, to identify patients with stable chest pain and known or suspected coronary artery disease who underwent resting echocardiography and had normal resting ECGs and no other indication for echocardiography. Results: Of the 15,529 referral outpatients who were evaluated at Mayo Clinic Rochester with chest pain, 3976 (25.6%) had resting echocardiograms. Eight hundred seventy of these 3976 patients (21.9%) had normal resting ECGs. Six hundred nineteen of these 870 patients (71.1%) had other indications for echocardiography. The remaining 251 patients (6.3% of all echocardiograms and 1.6% of all patie...
The impact of low- versus standard-volume bowel preparation on participation in primary screening colonoscopy: a randomized health services study
Authors: Małgorzata Pisera, Robert Franczyk, Paulina Wieszczy, Marcin Polkowski, Maciej Rupinski, Anna Chaber-Ciopinska, Bronislaw Kotowski, Zbigniew Kula, Slawomir Kielek, Marek Buszkiewicz, Maria Rupinska, Jaroslaw Kobiela, Michal Kaminski, Jaroslaw Regula
Journal: Endoscopy (2019)

Abstract Background The aim of this study was to evaluate the impact of low-volume vs. standard-volume bowel preparation on participation in screening colonoscopy, bowel preparation quality, and lesion detection rates. Methods This was a multicenter, randomized, health services study within the population-based primary colonoscopy screening program in Poland. Individuals aged 55 – 62 years were randomized in a 1:1 ratio to bowel preparation with a low-volume (0.3 L sodium picosulfate with magnesium citrate) or standard-volume (4 L polyethylene glycol) regimen and then invited to participate in screening colonoscopy. The primary outcome measure was the rate of participation in screening colonoscopy. Compliance with the assigned bowel preparation, bowel preparation quality, and lesion detection rates were also evaluated. Results A total of 13 621 individuals were randomized and 13 497 were analyzed (6752 in the low-volume group and 6745 in the standard-volume group). The participation rate (16.6 % vs. 15.5 %; P = 0.08) and compliance rate (93.3 % vs. 94.1 %; P = 0.39) did not differ significantly between the groups. In the low-volume group, fewer participants had adequate bowel preparation compared with the standard-volume group (whole colon 79.0 % vs. 86.4 %, P &lt; 0.001; proximal colon 80.1 % vs. 87.3 %, P &lt; 0.001). Detection rates of advanced adenoma (AADR) and advanced serrated polyps (ASPDR) were lower in the low-volume group than in the standard-volume group (AADR in the proximal colon 2.6 % vs. 4.3 %, P = 0.02; ASPDR in the whole colon 2.0 % vs. 3.3 %, P = 0.04; ASPDR in the proximal colon 1.0 % vs. 1.9 %, P = 0.048). Conclusion When compared with a standard-volume bowel preparation with polyethylene glycol, low-volume bowel preparation with sodium picosulfate/magnesium citrate did not improve participation rate or lesion detection rates, and negatively affected bowel preparation quality.
Influence of the initial level of consciousness on early, goal-directed mobilization: a post hoc analysis
Authors: Stefan J. Schaller, Flora T. Scheffenbichler, Somnath Bose, Nicole Mazwi, Hao Deng, Franziska Krebs, Christian L. Seifert, George Kasotakis, Stephanie D. Grabitz, Nicola Latronico, Timothy Houle, Manfred Blobner, Matthias Eikermann
Journal: Intensive Care Medicine (2019)