tbuckley/cabot-search huggingface dataset:
Abstract P4-01-14: Influence of radiotherapy on residual circulating epithelial tumor cells (CETCs) and their programmed cell death ligand 1 (PD-L1) status in breast cancer patients
Authors: Dorothea Schott, Monika Pizon, Ulrich Pachmann, Katharina Pachmann, Matthias Mäurer
Journal: Cancer Research (2020)

Abstract Background: Preclinical studies have suggested that radiotherapy followed by immunotherapy could be a promising strategy for synergistic enhancement of treatment efficacy. Radiation induces immunogenic changes in cancer cells which can lead to adaptive up-regulation of PD-L1 expression. Moreover, radiotherapy reduces not only local recurrence but even more distant relapse indicating its influence also on the residual occult tumor such as circulating tumor cells. For this reason the aim of this study was to determine the PD-L1 status on CETCs before and during radiotherapy. Methods: CETCs were determined in 54 primary breast cancer patients in early and locally advanced stages. The number of CETCs and their expression of PDL-L1 were investigated using the maintrac method. The fraction of PD-L1 positive CETCs was assessed prior to (baseline), 3 and 6 weeks after the start of radiotherapy. Results: We found an association between the PD-L1 status on CETCs and aggressiveness of cancer disease before radiotherapy. Patients with positive lymph node status had more PD-L1 positive CETCs as compared to patients with negative lymph nodes (mean 73 vs. 50, p&amp;lt;0.01). HER2 expression of the primary tumor was also positively correlated with PD-L1 expression. Lower numbers of CETCs were detected in patients who had not received chemotherapy or adjuvant chemotherapy before radiation than in those who received neoadjuvant chemotherapy (median 20 vs 25 vs 120 CETC/100µl blood, p&amp;lt;0.001). Surprisingly, the fraction of PD-L1 positive CETC decreased during radiotherapy only in patients who had received neoadjuvant chemotherapy. Conclusion: The number of CETCs and the fraction of PD-L1 positive CETCs were higher in patients who had received neoadjuvant chemotherapy and radiotherapy reduced both measured biomarkers. In the future PD-1/PD-L1 checkpoint inhibitors after radiotherapy might have additional benefit in breast cancer patients. Citation Format: Dorothea Schott, Monika Pizon, Ulrich Pachmann, Katharina Pachmann, Matthias Mäurer. Influence of radiotherapy on residual circulating epithelial tumor cells (CETCs) and their programmed cell death ligand 1 (PD-L1) status in breast cancer patients [abstract]. In: Proceedings of the 2019 San Antonio Breast Cancer Symposium; 2019 Dec 10-14; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2020;80(4 Suppl):Abstract nr P4-01-14.
Completeness of tuberculosis (TB) notification: inventory studies and capture-recapture analyses, six European Union countries, 2014 to 2016
Authors: Masja Straetemans, Mirjam I Bakker, Sandra Alba, Christina Mergenthaler, Ente Rood, Peter H Andersen, Henrieke Schimmel, Aleksandar Simunovic, Petra Svetina, Carlos Carvalho, Outi Lyytikäinen, Ibrahim Abubakar, Ross J Harris, Csaba Ködmön, Marieke J van der Werf, Rob van Hest
Journal: Eurosurveillance (2020)

BackgroundProgress towards the World Health Organization's End TB Strategy is monitored by assessing tuberculosis (TB) incidence, often derived from TB notification, assuming complete case detection and reporting. This assumption is unlikely to hold in many settings, including European Union (EU) countries.AimWe aimed to assess observed and estimated completeness of TB notification through inventory studies and capture-recapture (CRC) methodology in six EU countries: Croatia, Denmark, Finland, the Netherlands, Portugal Slovenia.MethodsWe performed record linkage, case ascertainment and CRC analyses of data collected retrospectively from at least three national TB-related registers in each country between 2014 and 2016.ResultsObserved completeness of TB notification by inventory studies was 73.9% in Croatia, 98.7% in Denmark, 83.6% in Finland, 81.6% in the Netherlands, 85.8% in Portugal and 100% in Slovenia. Subsequent CRC analysis estimated completeness of TB notification to be 98.4% in Denmark, 76.5% in Finland and 77.0% in Portugal. In Croatia, CRC analyses produced implausible results while in the Netherlands and Slovenia, it was methodologically considered not meaningful.ConclusionInventory studies and CRC methodology suggest a TB notification completeness between 73.9% and 100% in the six EU countries. Mandatory reporting by clinicians and laboratories, and cross-checking of registers, strongly contributes to accurate notification rates, but hospital episode registers likely contain a considerable proportion of false-positive TB records and are thus less useful. Further strengthening routine surveillance to count TB cases, i.e. incidence, accurately by employing record-linkage of high-quality TB registers should make CRC studies obsolete in EU countries.
Hepatopancreatoduodenectomy – Lessons with 40 patients over 15 years
Authors: Eduardo Fernandes, Munique Siqueira, Felipe Mello, Ronaldo Andrade, Camila Girao, Leandro Pimentel, Camilla Cesar, Caio Wierzchon, Jose Cardoso, Victor Diniz, Maria Monachesi, Camila Kyt, Mariana Abrahao
Journal: International Journal of Surgery (2020)
<i>Notes from the Field:</i> Nationwide Hepatitis E Outbreak Concentrated in Informal Settlements — Namibia, 2017–2020
Authors: Nirma D. Bustamante, Selma Robert Matyenyika, Leigh Ann Miller, Matthew Goers, Puumue Katjiuanjo, Kakehongo Ndiitodino, Emmy-Else Ndevaetela, Undjee Kaura, Kofi Mensah Nyarko, Lilliane Kahuika-Crentsil, Bernard Haufiku, Thomas Handzel, Eyasu H. Teshale, Eric J. Dziuban, Benetus T. Nangombe, Megan G. Hofmeister
Journal: MMWR Morbidity and Mortality Weekly Report (2020)

This hepatitis E outbreak has developed into Namibia's first reported nationwide outbreak and is a protracted event occurring mainly in informal settlements with poor water, sanitation, and hygiene conditions.
Exosomal noncoding RNAs in Glioma: biological functions and potential clinical applications
Authors: Jian Cheng, Jinli Meng, Lei Zhu, Yong Peng
Journal: Molecular Cancer (2020)

Abstract Gliomas are complex and heterogeneous brain tumors with poor prognosis. Glioma cells can communicate with their surroundings to create a tumor-permissive microenvironment. Exosomes represent a new means of intercellular communication by delivering various bioactive molecules, including proteins, lipids and nucleic acids, and participate in tumor initiation and progression. Noncoding RNAs (ncRNAs) including microRNA, long-noncoding RNA, and circular RNA, account for a large portion of human transcriptome and play important roles in various pathophysiological processes, especially in cancers. In addition, ncRNAs can be selectively packaged, secreted and transferred between cells in exosomes and modulate numerous hallmarks of glioma, such as proliferation, invasion, angiogenesis, immune-escape, and treatment resistance. Hence, the strategies of specifically targeting exosomal ncRNAs could be attractive therapeutic options. Exosomes are able to cross the blood brain barrier (BBB), and are readily accessible in nearly all types of human biofluids, which make them the promising biomarkers for gliomas. Additionally, given the biocompatibility of exosomes, they can be engineered to deliver therapeutic factors, such as RNA, proteins and drugs, to target cells for therapeutic applications. Here, we reviewed current research on the roles of exosomal ncRNAs in glioma progression. We also discussed their potential clinical applications as novel biomarkers and therapeutics.
<i>Notes from the Field:</i> Ongoing Cluster of Highly Related Disseminated Gonococcal Infections — Southwest Michigan, 2019
Authors: William D. Nettleton, James B. Kent, Kathryn Macomber, Mary-Grace Brandt, Kelly Jones, Alison D. Ridpath, Brian H. Raphael, Eden V. Wells
Journal: MMWR Morbidity and Mortality Weekly Report (2020)

Gonorrhea is a sexually transmitted infection that rarely can spread to other parts of the body and cause serious complications. In addition to prevention, early diagnosis and treatment might prevent severe disease and complications.
Abstract P4-07-09: Identification and functional analysis of interleukin-1 (IL-1) induced gene expression pattern in breast cancer (BCa) and prostate cancer (PCa) cells
Authors: Afshan Fathima Nawas, Mohammed Kanchwala, Shayna Thomas-Jardin, Haley Dahl, Nicole Roos, Monica Bautista, Ally Wong, Chao Xing, Nikki Delk
Journal: Cancer Research (2020)

Abstract Breast cancer (BCa) and prostate cancer (PCa) are both hormone receptor (HR) driven cancers with similar etiology, where tumor microenvironment inflammation promotes both BCa and PCa progression. Interleukin-1 (IL-1) is an inflammatory cytokine present in the tumor microenvironment, is elevated in BCa and PCa patient tumor tissue, correlates with poor prognosis, and inversely correlates with HR expression in tumor tissue. We have shown that IL-1 represses the BCa and PCa therapeutic targets, Estrogen Receptor Alpha (ERα) and Androgen Receptor (AR), respectively, in PCa and BCa cell lines; yet the cells remain viable. Thus, we hypothesize that IL-1 induces similar molecular responses in BCa and PCa cells that promote HR independence and subsequent treatment resistance. To address our hypothesis, we performed RNA sequencing of HR positive (HR+) BCa and PCa cell lines treated with IL-1 and compared IL-1-modulated gene expression patterns with the basal gene expression of HR negative (HR-) BCa and PCa cell lines. Our bioinformatics analysis revealed a suite of 350 genes that, based on ontology, promote inflammation response, angiogenesis, oxidative stress response, and cell motility. We chose two IL-1-induced genes from the genes list, p62 and SOX9, for functional analysis. p62 is an antioxidant and autophagy-related scaffold protein and SOX9 is an embryonic transcription factor. We performed p62 and SOX9 siRNA and found that loss of p62 or SOX9 reduce cell viability in HR- cell lines. We also found that the FDA approved p62-targeting drug, verteporfin, reduces cell viability in HR- cells line. Thus, our 350 genes list revealed alternative therapeutic targets for HR-independent cells, including BCa or PCa patients that might evolve HR-independence due to inflammation. Citation Format: Afshan Fathima Nawas, Mohammed Kanchwala, Shayna Thomas-Jardin, Haley Dahl, Nicole Roos, Monica Bautista, Ally Wong, Chao Xing, Nikki Delk. Identification and functional analysis of interleukin-1 (IL-1) induced gene expression pattern in breast cancer (BCa) and prostate cancer (PCa) cells [abstract]. In: Proceedings of the 2019 San Antonio Breast Cancer Symposium; 2019 Dec 10-14; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2020;80(4 Suppl):Abstract nr P4-07-09.
Double Counting of Patients in Meta-analyses of Observational Studies—Reply
Authors: Nico Gagelmann, Nicolaus Kröger
Journal: JAMA Oncology (2020)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Oncology HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Oncology journal
Surgeon Attitudes and Beliefs Toward Abdominal Wall Hernia Repair in Female Patients of Childbearing Age
Authors: Sara M. Jafri, C. Ann Vitous, Lesly A. Dossett, Claire Seven, Michael J. Englesbe, Anne Sales, Dana A. Telem
Journal: JAMA Surgery (2020)

Residents were more likely to report discrimination if female (odds ratio [OR], 1.48 [95% CI, 1.27-1.74];P < .001),nonwhite (Black: OR, 20.91 [95% CI, 14.39-30.38];P < .001;Hispanic: OR, 2.62 [95% CI, 1.99-3.47];P < .001;Asian: OR, 6.29 [95% CI, 5.18-7.63];P < .001),more senior (program year 2 or 3: OR, 1.30 [95% CI, 1.08-1.57];P = .005;program year 4 or 5: OR, 1.57 [95% CI, 1.28-1.92];P < .001;compared with program year 1), and after experiencing violations of the 80-hour duty limit (>5 times in 6 months: OR, 2.26 [95% CI, 1.69-3.02];P < .001;vs never; Table 2).Stratification by sex revealed higher odds in women for every nonwhite race/ethnicity (black men: OR, 18.6 [95% CI, 11.44-30.32]vs black women: OR, 23.93 [95% CI, 13.93-41.12];Hispanic men: OR, 2.32 [95% CI, 1.57-3.42]vs Hispanic women: 3.09 [95% CI, 2.06-4.64];Asian men: OR, 5.66 [95% CI, 4.36-7.34]vs Asian women: 7.35 [95% CI, 5.57-9.72]).Geographic location, program type (academic, community, or military), and the racial/ethnic compositions of the faculty and residency members were not associated with the likelihood of experiencing discrimination.Residents who experienced discrimination reported higher rates of burnout (51.6% vs 40.0%;P < .001),thoughts of attrition (16.2% vs 10.1%; P < .001),and suicidal thoughts (6.5% vs 3.8%; P < .001).
Mobile Health Technology to Improve Care for Patients With Atrial Fibrillation
Authors: Yutao Guo, Deirdre A. Lane, Limin Wang, Hui Zhang, Hao Wang, Wei Zhang, Jing Wen, Yunli Xing, Fang Wu, Yunlong Xia, Tong Liu, Fan Wu, Zhaoguang Liang, Fan Liu, Yujie Zhao, Rong Li, Xin Li, Lili Zhang, Jun Guo, Girvan Burnside, Yundai Chen, Gregory Y.H. Lip, Yutao Guo, Gregory Y.H. Lip, Deirdre A. Lane, Yundai Chen, Liming Wang, Jens Eckstein, G Neil Thomas, Liu Tong, Feng Mei, Liu Xuejun, Li Xiaoming, Shan Zhaoliang, Shi Xiangming, Zhang Wei, Xing Yunli, Wen Jing, Wu Fan, Yang Sitong, Jin Xiaoqing, Yang Bo, Bai Xiaojuan, Jiang Yuting, Liu Yangxia, Song Yingying, Tan Zhongju, Yang Li, Luan Tianzhu, Niu Chunfeng, Zhang Lili, Li Shuyan, Wang Zulu, Xv Bing, Liu Liming, Jin Yuanzhe, Xia Yunlong, Chen Xiaohong, Wu Fang, Zhong Lina, Sun Yihong, Jia Shujie, Li Jing, Li Nan, Li Shijun, Liu Huixia, Li Rong, Liu Fan, Ge Qingfeng, Guan Tianyun, Wen Yuan, Li Xin, Ren Yan, Chen Xiaoping, Chen Ronghua, Shi Yun, Zhao Yulan, Shi Haili, Zhao Yujie, Wang Quanchun, Sun Weidong, Wei Lin, Esther Chan, Shan Guangliang, Yao Chen, Zong Wei, Chen Dandi, Han Xiang, Xu Anding, Fan Xiaohan, Yu Ziqiang, Gu Xiang, Ge Fulin
Journal: Journal of the American College of Cardiology (2020)
Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA
Authors: M.C. Liu, G.R. Oxnard, E.A. Klein, C. Swanton, M.V. Seiden, Minetta C. Liu, Geoffrey R. Oxnard, Eric A. Klein, David Smith, Donald Richards, Timothy J. Yeatman, Allen L. Cohn, Rosanna Lapham, Jessica Clement, Alexander S. Parker, Mohan K. Tummala, Kristi McIntyre, Mikkael A. Sekeres, Alan H. Bryce, Robert Siegel, Xuezhong Wang, David P. Cosgrove, Nadeem R. Abu-Rustum, Jonathan Trent, David D. Thiel, Carlos Becerra, Manish Agrawal, Lawrence E. Garbo, Jeffrey K. Giguere, Ross M. Michels, Ronald P. Harris, Stephen L. Richey, Timothy A. McCarthy, David M. Waterhouse, Fergus J. Couch, Sharon T. Wilks, Amy K. Krie, Rama Balaraman, Alvaro Restrepo, Michael W. Meshad, Kimberly Rieger-Christ, Travis Sullivan, Christine M. Lee, Daniel R. Greenwald, William Oh, Che-Kai Tsao, Neil Fleshner, Hagen F. Kennecke, Maged F. Khalil, David R. Spigel, Atisha P. Manhas, Brian K. Ulrich, Philip A. Kovoor, Christopher Stokoe, Jay G. Courtright, Habte A. Yimer, Timothy G. Larson, Charles Swanton, Michael V. Seiden, Steven R. Cummings, Farnaz Absalan, Gregory Alexander, Brian Allen, Hamed Amini, Alexander M. Aravanis, Siddhartha Bagaria, Leila Bazargan, John F. Beausang, Jennifer Berman, Craig Betts, Alexander Blocker, Joerg Bredno, Robert Calef, Gordon Cann, Jeremy Carter, Christopher Chang, Hemanshi Chawla, Xiaoji Chen, Tom C. Chien, Daniel Civello, Konstantin Davydov, Vasiliki Demas, Mohini Desai, Zhao Dong, Saniya Fayzullina, Alexander P. Fields, Darya Filippova, Peter Freese, Eric T. Fung, Sante Gnerre, Samuel Gross, Meredith Halks-Miller, Megan P. Hall, Anne-Renee Hartman, Chenlu Hou, Earl Hubbell, Nathan Hunkapiller, Karthik Jagadeesh, Arash Jamshidi, Roger Jiang, Byoungsok Jung, TaeHyung Kim, Richard D. Klausner, Kathryn N. Kurtzman, Mark Lee, Wendy Lin, Jafi Lipson, Hai Liu, Qinwen Liu, Margarita Lopatin, Tara Maddala, M. Cyrus Maher, Collin Melton, Andrea Mich, Shivani Nautiyal, Jonathan Newman, Joshua Newman, Virgil Nicula, Cosmos Nicolaou, Ongjen Nikolic, Wenying Pan, Shilpen Patel, Sarah A. Prins, Richard Rava, Neda Ronaghi, Onur Sakarya, Ravi Vijaya Satya, Jan Schellenberger, Eric Scott, Amy J. Sehnert, Rita Shaknovich, Avinash Shanmugam, K.C. Shashidhar, Ling Shen, Archana Shenoy, Seyedmehdi Shojaee, Pranav Singh, Kristan K. Steffen, Susan Tang, Jonathan M. Toung, Anton Valouev, Oliver Venn, Richard T. Williams, Tony Wu, Hui H. Xu, Christopher Yakym, Xiao Yang, Jessica Yecies, Alexander S. Yip, Jack Youngren, Jeanne Yue, Jingyang Zhang, Lily Zhang, Lori (Quan) Zhang, Nan Zhang, Christina Curtis, Donald A. Berry
Journal: Annals of Oncology (2020)

Early cancer detection could identify tumors at a time when outcomes are superior and treatment is less morbid. This prospective case-control sub-study (from NCT02889978 and NCT03085888) assessed the performance of targeted methylation analysis of circulating cell-free DNA (cfDNA) to detect and localize multiple cancer types across all stages at high specificity.
Reply to Rizzatti et al.
Authors: Juliana Yang, Mouen A. Khashab
Journal: Endoscopy (2020)

See also: Safety and efficacy of the use of lumen-apposing metal stents in the management of postoperative fluid collections: a large, international, multicenter studyEndoscopy 2019; 51(08): 715-721DOI: 10.1055/a-0924-5591 See also: Which stent to use for the management of pancreatic pseudocysts? Time for randomized controlled studiesEndoscopy 2020; 52(04): 321-321DOI: 10.1055/a-1103-1938 Corrected by: Correction: Reply to Rizzatti et al.Endoscopy 2020; 52(04): C2-C2DOI: 10.1055/a-1149-8023
Readmission and death in patients admitted with new‐onset versus worsening of chronic heart failure: insights from a nationwide cohort
Authors: Jawad H. Butt, Emil L. Fosbøl, Thomas A. Gerds, Charlotte Andersson, John J.V. McMurray, Mark C. Petrie, Finn Gustafsson, Christian Madelaire, Søren Lund Kristensen, Gunnar H. Gislason, Christian Torp‐Pedersen, Lars Køber, Morten Schou
Journal: European Journal of Heart Failure (2020)
Precise Spatiotemporal Control of Nodal Na+ Channel Clustering by Bone Morphogenetic Protein-1/Tolloid-like Proteinases
Authors: Yael Eshed-Eisenbach, Jerome Devaux, Anna Vainshtein, Ofra Golani, Se-Jin Lee, Konstantin Feinberg, Natasha Sukhanov, Daniel S. Greenspan, Keiichiro Susuki, Matthew N. Rasband, Elior Peles
Journal: Neuron (2020)
Malnutrition trends in Rohingya children aged 6–59 months residing in informal settlements in Cox’s Bazar District, Bangladesh: An analysis of cross-sectional, population-representative surveys
Authors: Eva Leidman, Md. Lalan Miah, Alexa Humphreys, Leonie Toroitich-van Mil, Caroline Wilkinson, Mary Chelang'at Koech, Henry Sebuliba, Muhammad Abu Bakr Siddique, Oleg Bilukha
Journal: PLoS Medicine (2020)

Background More than 700,000 ethnic Rohingya have crossed the border from Rakhine State, Myanmar to Cox's Bazar District, Bangladesh, following escalated violence by Myanmar security forces. The majority of these displaced Rohingya settled in informal sites on previously forested land, in areas without basic infrastructure or access to services. Methods and findings Three cross-sectional population-representative cluster surveys were conducted, including all informal settlements of Rohingya refugees in the Ukhia and Teknaf Upazilas of Cox's Bazar District. The first survey was conducted during the acute phase of the humanitarian response (October–November 2017), and the second and third surveys were conducted 6 (April–May 2018) and 12 (October–November 2018) months later. Anthropometric indices (weight, height, mid-upper arm circumference [MUAC], oedema) and haemoglobin (Hb) were measured in children aged 6–59 months following standard procedures. Final samples for survey rounds 1, 2, and 3 (R1, R2, and R3) included 1,113, 628, and 683 children, respectively, of which approximately half were male (50.7%–53.5% per round) and a third were 6–23 months of age (32.4%–33.3% per round). Prevalence of global acute malnutrition (GAM) as assessed by weight for height in R2 (12.1%, 95% CI: 9.6–15.1) and R3 (11.0%, 95% CI: 8.4–14.2) represent a significant decline from the observed prevalence in R1 (19.4%, 95% CI: 16.8–22.3) (p < 0.001 for both comparisons). Overall, the prevalence of anaemia significantly declined (p < 0.001) between the first 2 rounds (47.9%, 95% CI: 44.1–51.7 and 32.3%, 95% CI: 27.8–37.1, respectively); prevalence increased significantly (p = 0.04) to 39.8% (95% CI, 34.1–45.4) during R3 but remained below R1 levels. Reported receipt of both fortified blended foods (12.8%) and micronutrient powders (10.3%) were low during R1 but increased significantly (p < 0.001 for both) within the first 6 months to 49.8% and 29.9%, respectively. Although findings demonstrate improvement in anthropometric indicators during a period in which nutrition programme coverage increased, causation cannot be determined from the cross-sectional design. Conclusions These data document significant improvements in both acute and micronutrient malnutrition among Rohingya children in makeshift settlements. These declines coincide with a scaleup of services aimed at prevention and treatment of malnutrition. Ongoing activities to improve access to nutritional services may facilitate further reductions in malnutrition levels to sustained below-crisis levels.
A Study of Basic Needs and Psychological Wellbeing of Medical Workers in the Fever Clinic of a Tertiary General Hospital in Beijing during the COVID-19 Outbreak
Authors: Jinya Cao, Jing Wei, Huadong Zhu, Yanping Duan, Wenqi Geng, Xia Hong, Jing Jiang, Xiaohui Zhao, Boheng Zhu
Journal: Psychotherapy and Psychosomatics (2020)
Bundled Interventions to Reduce Surgical Site Infections Are Effective and Urgently Needed
Authors: Joseph D. Forrester
Journal: JAMA Network Open (2020)

Randy W. Loftus, MD; Franklin Dexter, MD, PhD; Michael J. Goodheart, MD; Megan McDonald, MD; John Keech, MD; Nicolas Noiseux, MD; Andrew Pugely, MD; William Sharp, MD; Mel Sharafuddin, MD; W. Thomas Lawrence, MD; Mark Fisher, MD; Patrick McGonagill, MD; Jennifer Shanklin, MD; Dionne Skeete, MD; Chad Tracy, MD; Bradley Erickson, MD; Thomas Granchi, MD; Lance Evans, BA; Eli Schmidt, BS; Joshua Godding, BA; Raven Brenneke, BS; Deanna Persons; Alexia Herber; Mark Yeager, MD; Brent Hadder, MD; Jeremiah R. Brown, PhD
Possible Vertical Transmission of SARS-CoV-2 From an Infected Mother to Her Newborn
Authors: Lan Dong, Jinhua Tian, Songming He, Chuchao Zhu, Jian Wang, Chen Liu, Jing Yang
Journal: JAMA (2020)

This case report describes birth of an infant with elevated anti–SARS-CoV-2 IgM antibodies and cytokine levels to a mother with polymerase chain reaction–confirmed coronavirus disease 2019 (COVID-19) despite no physical contact.