Annals On Call - SGLT2 Inhibitors: The Good, the Bad, and the Ugly
Authors: Robert M. Centor, Katherine Tuttle
Journal: Annals of Internal Medicine (2019)

Web Exclusives6 August 2019Annals On Call - SGLT2 Inhibitors: The Good, the Bad, and the UglyFREERobert M. Centor, MD and Katherine Tuttle, MDRobert M. Centor, MDHuntsville Regional Medical Campus, University of Alabama Birmingham School of Medicine, Birmingham, Alabama (R.M.C.)Search for more papers by this author and Katherine Tuttle, MDWashington State University, Pullman, Washington (K.T.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/A19-0011 SectionsAboutVisual Abstract ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail In this episode of Annals On Call, Dr. Centor discusses the risks and benefits of using SGLT2 inhibitors to treat patients with type 2 diabetes with Dr. Katherine Tuttle, an endocrinologist and nephrologist at Washington State University.Annals articles discussed include...Fournier Gangrene Associated With Sodium–Glucose Cotransporter-2 Inhibitors: A Review of Spontaneous Postmarketing Cases: https://annals.org/aim/fullarticle/2732837/fournier-gangrene-associated-sodium-glucose-cotransporter-2-inhibitors-review-spontaneousEuglycemic Ketoacidosis Caused by Sodium–Glucose Cotransporter 2 Inhibitors: A Case Report: https://annals.org/aim/fullarticle/2557195/euglycemic-ketoacidosis-caused-sodium-glucose-cotransporter-2-inhibitors-case-reportMentioned in the podcast...EMPA-REG: www.nejm.org/doi/full/10.1056/NEJMoa1504720CANVAS Program canagliflozin trial: www.nejm.org/doi/full/10.1056/NEJMoa1611925DECLARE dapagliflozin trial: www.nejm.org/doi/full/10.1056/NEJMoa1812389CREDENCE: www.nejm.org/doi/full/10.1056/NEJMoa1811744About Annals On CallAnnals On Call focuses on a clinically influential article published in Annals of Internal Medicine. Dr. Robert Centor shares his own perspective on the material and interviews topic area experts to discuss, debate, and share diverse insights about patient care and health care delivery.For more information on Annals On Call and for more episodes, visit go.annals.org/OnCall. Comments0 CommentsSign In to Submit A Comment Author, Article, and Disclosure InformationAffiliations: Huntsville Regional Medical Campus, University of Alabama Birmingham School of Medicine, Birmingham, Alabama (R.M.C.)Washington State University, Pullman, Washington (K.T.)Disclosures: Dr. Centor has disclosed the following: Honoraria: Medscape. Dr. Tuttle has disclosed the following: Honoraria: Eli Lilly and Company. Consultantship: Eli Lilly and Company, Boehringer Ingelheim, AstraZeneca, Gilead, and Goldfinch BioEditors' Disclosures: Christine Laine, MD, MPH, Editor in Chief, reports that her spouse has stock options/holdings with Targeted Diagnostics and Therapeutics. Darren B. Taichman, MD, PhD, Executive Editor, reports that he has no financial relationships or interests to disclose. Cynthia D. Mulrow, MD, MSc, Senior Deputy Editor, reports that she has no relationships or interests to disclose. Jaya K. Rao, MD, MHS, Deputy Editor, reports that she has stock holdings/options in Eli Lilly and Pfizer. Catharine B. Stack, PhD, MS, Deputy Editor, Statistics, reports that she has stock holdings in Pfizer, Johnson & Johnson, and Colgate-Palmolive. Christina C. Wee, MD, MPH, Deputy Editor, reports employment with Beth Israel Deaconess Medical Center. Sankey V. Williams, MD, Deputy Editor, reports that he has no financial relationships or interests to disclose. Yu-Xiao Yang, MD, MSCE, Deputy Editor, reports that he has no financial relationships or interest to disclose. Previousarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoEuglycemic Ketoacidosis Caused by Sodium–Glucose Cotransporter 2 Inhibitors: A Case Report Shane A. Bobart , Benjamin Gleason , Nydia Martinez , Keith Norris , and Sandra F. Williams Fournier Gangrene Associated With Sodium–Glucose Cotransporter-2 Inhibitors Susan J. Bersoff-Matcha , Christine Chamberlain , Christian Cao , Cindy Kortepeter , and William H. Chong Annals On Call - SGLT-2 Revisited: Diabetes Management in Chronic Kidney Disease Robert M. Centor , Katherine R. Tuttle , and Jonathan Himmelfarb Metrics 6 August 2019Volume 171, Issue 3Page: OC1KeywordsDiagnostic techniquesDisclosureHealth carePatientsType 2 diabetes ePublished: 6 August 2019 Issue Published: 6 August 2019 Copyright & PermissionsCopyright © 2019 by American College of Physicians. All Rights Reserved.Loading ...