AB0889 SARCOPENIA AND HIP FRACTURE IN GERIATRIC POPULATION
Authors: K. Boskovic, S. Pantelinac, S. Tomasevic-Todorovic, T. Spasojevic, D. Simic-Panic, N. Boskovic
Journal: Annals of the Rheumatic Diseases (2020)

Background: Sarcopenia is a loss of skeletal muscle mass, muscle strength, and function, with an impact on the quality of life, increased risk of bone loss and fracture, which is associated with normal aging. Objectives: To determine the effect of sarcopenia on the recovery of patients after hip fracture, their fitness, functionality, and quality of life Methods: A prospective study had 60 patients with hip fractures of both sexes,&gt; 65 years of age (70.8), in the experimental group of patients with sarcopenia and the control group without sarcopenia. All anthropometric measurements were performed: BMI (kg / m2), waist circumference, the volume of the upper arm and lower leg muscle mass, handgrip force (kg) - dynamometry. The following questionnaires were used to assess functionality, mobility, and quality of life: Health assessment questionnaire (HAQ), Harrison hip score (HHS), Sarcopenia and Quality of life (SarQol) Results: Muscle mass (BMI) was significantly lower in the experimental group patients (p &lt;0.005) compared to the control group. The clamp strength measured by the dynamometer was significantly lower in patients with hip fractures (p &lt;0.005) compared to the control group. About 2/3 of the subjects with sarcopenia and hip fracture have a severe and complete physical disability. There was a significant difference in all domains of quality of life between subjects with hip fractures and the control group due to the presence of sarcopenia (p &lt;0.005). Conclusion: The presence of sarcopenia indicates consequently reduced functionality and a degree of disability in patients with hip fractures, slows recovery and increases the need for mobility aids, thus extending hospital stay and patient recovery. References: [1]He H, Liu Y, Tian Q, Papasian CJ, Hu T, Deng HW. Relationship of sarcopenia and body composition with osteoporosis. Osteoporos Int. 2016 Feb; 27(2):473–82. https://doi.org/10.1007/s00198-015-3241-8 PMID: 26243357 [2]Oliveira A, Vaz C. The role of sarcopenia in the risk of osteoporotic hip fracture. Clin Rheumatol. 2015 Oct; 34(10):1673–80. https://doi.org/10.1007/s10067-015-2943-9 PMID: 25912213 [3]Tarantino U, Piccirilli E, Fantini M, Baldi J, Gasbarra E, Bei R. Sarcopenia and fragility fractures: molecular and clinical evidence of the bone-muscle interaction. J Bone Joint Surg Am. 2015 Mar 4; 97(5):429–37. https://doi.org/10.2106/JBJS.N.00648 PMID: 25740034 Benichou O, Lord SR. Rationale for Strengthening Muscle to Prevent Falls and Fractures: A Review of the Evidence. Calcif Tissue Int. 2016 Jun; 98(6):531–45. https://doi.org/10.1007/s00223-016-0107-9 PMID: 26847435 [4]Hirschfeld HP, Kinsella R, Duque G. Osteosarcopenia: where bone, muscle, and fat collide. Osteoporos Int. 2017 Oct; 28(10):2781–2790. https://doi.org/10.1007/s00198-017-4151-8 PMID: 28733716 [5]Rantanen T, Volpato S, Ferrucci L, Heikkinen E, Fried LP, Guralnik JM. Handgrip strength and causespecific and total mortality in older disabled women: exploring the mechanism. J Am Geriatr Soc. 2003 May; 51(5):636–41. https://doi.org/10.1034/j.1600-0579.2003.00207.x PMID: 12752838 [6]Syddall H, Cooper C, Martin F, Briggs R, Aihie Sayer A. Is grip strength a useful single marker of frailty? Age Ageing. 2003 Nov; 32(6):650–6. https://doi.org/10.1093/ageing/afg111 PMID: 14600007 [7]Chen LK, Liu LK, Woo J, Assantachai P, Auyeung TW, Bahyah KS, et al. Sarcopenia in Asia: consensus report of the Asian Working Group for Sarcopenia. J Am Med Dir Assoc. 2014 Feb; 15(2):95–101. https://doi.org/10.1016/j.jamda.2013.11.025 PMID: 24461239 [8]Wehren LE, Hawkes WG, Hebel JR, Orwig DL, Magaziner J. Bone mineral density, soft tissue body composition, strength, and functioning after hip fracture. J Gerontol A Biol Sci Med Sci. 2005 Jan; 60 (1):80–4. https://doi.org/10.1093/gerona/60.1.80 PMID: 15741287 Disclosure of Interests: None declared