tbuckley/cabot-search huggingface dataset:
AB1378-HPR EFFECT OF CLINICAL CHARACTERISTICS, HABITS, PHYSICAL ACTIVITY LEVELS AND FUNCTIONAL CAPACITY ON QUALITY OF LIFE IN SYSTEMIC SCLEROSIS PATIENTS
Authors: Hazal Yakut, Sevgi Özalevli, Ahmet Merih Birlik
Journal: Annals of the Rheumatic Diseases (2019)

<h3>Background</h3> In patients with Systemic sclerosis (SSc), many factors such as inactivity, smoking, gastrointestinal system involvement are reported to have an adverse effect on overall health related quality of life, and quality of life is in line with the prognosis of the disease (1,2). <h3>Objectives</h3> The aim of this study was to investigate the effect of clinical characteristics, habits, physical activity levels and functional capacity of patients with SSc on quality of life. <h3>Methods</h3> Twenty-tree SSc patients were included in the study. The ages of patients, the amount of cigarette consumption, duration of diagnosis and body mass indexes (BMI) were questioned and recorded. Functional capacities of patients were measured by 6 Minute Walking Test (6MWT). Physical activity levels of patients were calculated using the International Physical Activity Questionnaire (IPAQ; using metabolic equivalent-MET). Quality of life was evaluated by the short form SF-36 quality of life questionnaire(SF-36 QoLQ). The SF-36 questionnaire was evaluated as two sub-scales, physical and mental. <h3>Results</h3> The mean age of the patients was 51.0011.10 years and the duration of diagnosis was 7.604.80 years, BMI was 26.606.37 kg/m<sup>2</sup> and amount of cigarette consumption was 6.023.30 packetyears. The mean physical activity levels (IPAQ) were 281.6860.45 MET, 6MWT distance were 435.3980.45 m, SF-36 QoLQ-physical were 32.4813.42 and SF-36 QoLQ-mental were 38.5611.42 score. It was found that there was a significant correlation between SF-36 QoLQ-physical and BMI (p =0.043, r =-0.426), 6DWT (p &lt;0.001, r= 0.737) and IPAQ (p =0.001, r = 0.647). There was a significant correlation between the SF-36 QoLQ-mental and 6MWT (p=0.020, r = 0.483) and IPAQ (p =0.002, r = 0.614). <h3>Conclusion</h3> Reduced levels of physical activity in SSc patients affect functional capacity. Reduced physical activity level and functional capacity decrease the quality of life of patients related to both physical and mental health. Physical health related quality of life of patients is negatively affected by the increase in BMI. Functional capacity, clinical characteristics, habits and physical activity levels should be evaluated and improved in treatment programs aimed at improving the overall health-related quality of life of patients. <h3>References</h3> [1] Turesson, C., &amp; Matteson, E. L. (2007). Cardiovascular risk factors, fitness and physical activity in rheumatic diseases. Current Opinion in Rheumatology, 19(2), 190196. [2] Hudson, M., Thombs, B. D., Steele, R., Panopalis, P., Newton, E., Baron, M., &amp; Canadian Scleroderma Research Group (2009). Health-related quality of life in systemic sclerosis: A systematicreview.ArthritisandRheumatism,61(8),11121120. https://doi.org/10.1002/art.24676 <h3>Disclosure of Interests</h3> None declared
A phase II, randomized study of nivolumab (NIVO) and Ipilimumab (IPI) versus NIVO, IPI and stereotactic body radiation therapy (SBRT) for metastatic Merkel cell carcinoma (MCC, NCT03071406): A preliminary report
Authors: S. Kim, N.I. Khushalani, Z. Eroglu, J. Russell, E. Wuthrick, J. Caudell, L. Harrison, M. Aoki, H. Shah, D. Blakaj, J. Markowitz, D.-T. Chen, J. Messina, T. Rose, K. Tsai, A.S. Brohl
Journal: Annals of Oncology (2019)
Abstract 13002: Hypoalbuminemia as a Predictor for Contrast-Induced Acute Kidney Injury Following Coronary Angiography
Authors: Jayakumar Sreenivasan, Mohammad S Khan, Jishanth Mattumpuram, Rohit Agrawal, Sreedevi P Harshakumar, Sagar Ranka, Jose Sleiman, Min Zhuo, Neha Yadav
Journal: Circulation (2018)

Introduction: Contrast-induced acute kidney injury (CI-AKI) is associated with increased mortality, morbidity and health care costs. Albumin, being an antioxidant, may have a protective role in pre...
Prediction of serious complications in patients with cancer and pulmonary embolism: Validation of the EPIPHANY index in a prospective cohort of patients from the PERSEO study
Authors: M. Sanchez Canovas, A. Fernández Montes, R. Morales Giménez, M. Cejuela Solís, D. Casado Elia, E. Coma Salvans, D. Gómez Sánchez, C. Sánchez Cendra, S. Sequero López, M. Orrillo Sarmiento, V. Arrazubi Arrula, M. Justo De la Peña, M. Biosca, D. Fernández Garay, A. Bernal Vidal, D. Moreno Muñoz, E. Martínez de Castro, P. Jimenez-Fonseca, A. Carmona Bayonas
Journal: Annals of Oncology (2019)
A phase III trial evaluating olanzapine 5 mg for the prevention of chemotherapy-induced nausea and vomiting in patients receiving cisplatin: J-FORCE study
Authors: H. Hashimoto, M. Abe, M. Nakao, H. Mizutani, Y. Sakata, Y. Fujita, T. Nishimura, K. Hirano, H. Okada, N. Inui, Y. Sakata, H. Iihara, S. Zenda, Y. Uchitomi, T. Yamaguchi, Y. Hoshina, T. Yanai, S. Iwasa, N. Yamamoto, Y. Ohe
Journal: Annals of Oncology (2019)
Abstract 11417: Elevated Serum Osteoprotegerin is Associated With Increased Left Ventricular Mass Index and Left Ventricular Diastolic Stiffness in African Americans: Insights From the Genetic Epidemiology Network of Arteriopathy (GENOA) Study
Authors: Daisuke Kamimura, Takeki Suzuki, Anna L Furniss, Michael E Griswold, Merry L Lindsey, Michael D Winniford, Kenneth R Butler, Thomas H Mosley, Michael E Hall
Journal: Circulation (2016)

Background: Osteoprotegerin (OPG) associates with a poor prognosis in patients that have already developed heart failure with preserved ejection fraction (HFpEF). OPG also associates with fibrosis and collagen cross-linking which increase diastolic stiffness in the left ventricle (LV). Little is known about the relationship of OPG and LV structure and function in African Americans who are disproportionately affected by HFpEF. We hypothesized that OPG may serve as an early indicator of developing LV hypertrophy and stiffening which are prominent precursors to HFpEF. Methods and Results: Our analysis included 1172 participants with preserved LV ejection fraction (EF &gt;50%) from the African American (Jackson) cohort of the Genetic Epidemiology Network of Arteriopathy (GENOA) Study (mean age 62.9 years, 72% female). LV diastolic stiffness was assessed by echocardiography using the recently developed diastolic wall strain (DWS) indicator calculated as (LV posterior wall thickness at end-systole - LV posterior wall thickness at end-diastole) / LV posterior wall thickness at end-systole. Associations between serum OPG levels and indices of LV structure and function were evaluated using a generalized linear mixed models (GLMM) accounting for clustering in siblings, and adjusted for possible confounders including age, gender, past history of hypertension and diabetes, current smoking status and estimated glomerular filtration rate (eGFR). OPG levels correlated with age, female sex, presence of hypertension and diabetes, lower eGFR, and higher N-terminal prohormone brain natriuretic peptide levels (p &lt;0.05 for all). Thus, higher OPG levels were associated with characteristics common in patients with HFpEF. Multivariable linear regression analysis revealed that after adjustment for covariates, higher OPG levels were associated with greater LV mass index and increased LV diastolic stiffness (p &lt;0.05, for all). Conclusions: Higher OPG levels associated with characteristics common in patients with HFpEF in African Americans. The serum OPG levels also significantly associated with known precursors to HFpEF, indicating a potential pathophysiologic role for OPG in the development of HFpEF in African Americans.
Abstract 1209: Bone Morphogenic Protein-4 is Elevated in Chronic Kidney Disease Patients with Coronary Artery Disease
Authors: T. C Woods, Christopher J White, Corey K Goldman
Journal: Circulation (2006)

Cross-sectional studies have demonstrated that the Framingham Risk Equation does not adequately predict the magnitude of the increased risk of cardiovascular disease seen in chronic kidney disease (CKD) patients, suggesting additional risk factors may be present in CKD patients. Recent studies suggest that the increased vascular calcification seen in CKD patients compared with the general population may play a role in the increased risk of cardiovascular events. One mechanism proposed for the induction of vascular calcification is the up-regulation of the bone morphogenic proteins (BMP) at the site of vascular calcification. We measured the levels of BMP-4 in the plasma of healthy volunteers (n=11) and patients with coronary artery disease (CAD) without CKD (n=10), CKD without CAD (n=6), and CKD with CAD (n=7). CKD was defined as Stage 3, 4, or 5 kidney disease using the National Kidney Foundation’s KDOQI classification. CAD was defined as a greater than 50% narrowing of a coronary artery determined angio...
Immunogenicity and optimal timing of 13-valent pneumococcal conjugate vaccination during adjuvant chemotherapy in gastric and colorectal cancer: A randomized controlled trial
Authors: W. Choi, J.G. Kim, S.-H. Beom, J.E. Hwang, H.-J. Shim, S.-H. Cho, M.-H. Shin, S.-H. Jung, I.-J. Chung, J.Y. Song, W.K. Bae
Journal: Annals of Oncology (2019)
KEYNOTE-905: A phase III study of cystectomy plus perioperative pembrolizumab versus cystectomy alone in cisplatin (cis)-ineligible patients (pts) with muscle-invasive bladder cancer (MIBC)
Authors: M. Galsky, A. Necchi, N.D. Shore, F. Witjes, K. Nam, J.L. Godwin, T.L. Frenkl, E.R. Plimack
Journal: Annals of Oncology (2019)
Clinicopathologic characteristics of immune colitis in melanoma patients treated with combination ipilimumab and anti-PD1 (IPI+PD1) and PD1 monotherapy
Authors: K.J. Nahar, R.V. Rawson, N. Sandanayake, S. Tattersal, M.S. Carlino, U. Palendira, R.A. Scolyer, G.V. Long, A.M. Menzies
Journal: Annals of Oncology (2019)
The extended/phase II study of safety and tolerability of proxalutamide (GT0918) in subjects with metastatic castrate resistant prostate cancer (mCRPC) who failed either abiraterone (Abi) or enzalutamide (Enza)
Authors: N.J. Vogelzang, N. Gabrail, Z. Malik, F. Volterra, L.T. Nordquist, R. Levin, P. Zhang, K. Zhou
Journal: Annals of Oncology (2019)
WRN mutated colorectal cancer (CRC) is characterized by a distinct molecular and immunological profile
Authors: A. Seeber, A. Puccini, J. Xiu, Y. Baca, G. Spizzo, K. Zimmer, H.J. Lenz, F. Battaglin, R.M. Goldberg, A. Grothey, A.F. Shields, M.E. Salem, J.L. Marshall, W.M. Korn, D. Wolf, F. Kocher
Journal: Annals of Oncology (2019)
Tumour stroma targeting and modulation by OMTX705 ADC, a novel and potent immunotherapeutic treatment of solid tumours
Authors: M. Fabre, C. Ferrer, S. Domínguez-Hormaetxe, R. Kontermann, K. Pfizenmaier, O. Seifer, M.D. Vivanco, S.-Y. Lee, P. López-Casas, M. Abbas, W. Richter, L. Simon, M. Hidalgo
Journal: Annals of Oncology (2019)
Patch testing hydroxyethyl (meth)acrylate
Authors: S. Rolls, M.M. Chowdhury, S. Cooper, P. Cousen, A.M. Flynn, S.A. Ghaffar, C.M. Green, A. Haworth, C. Holden, G.A. Johnston, K. Naidoo, D.I. Orton, C. Reckling, R.A. Sabroe, M. Scorer, N.M. Stone, D. Thompson, S. Wakelin, M. Wilkinson, D.A. Buckley
Journal: British Journal of Dermatology (2019)

Contact allergy occurs when the skin comes into contact with allergens (chemicals that cause allergy), causing sensitisation. This means that if the skin comes into contact with the same allergen again, it can develop an eczema-like reaction known as allergic contact dermatitis (ACD), which affects 20% of people. Patch testing is used by dermatologists to find out what the substance causing the reaction might be. This is done by applying a range of known allergens to patches of the skin to see which trigger a reaction. The baseline (standard) series of patch test allergens is recommended in everyone undergoing patch testing and aims to include the most common allergens which cause ACD. (Meth)acrylate chemicals are the key ingredients in acrylic nails, gel nails and gel polish nails. There are different types of meth(acrylates). The authors of this study from 15 centres in the U.K. decided to add 2-hydroxyethyl methacrylate (2-HEMA) 2% in petrolatum (pet.) to the baseline patch test series in 2016-7, aiming to detect ACD in patients using acrylic nails. Patients with a history of (meth)acrylate exposure, or who tested positive to 2-HEMA, were then selectively tested with a further short series of eight (meth)acrylate allergens. Of 5,920 patients, 1.7% (102) were allergic to 2-HEMA and 2.4% (140) to at least one (meth)acrylate. (Meth)acrylate allergy would have been missed in 0.6% of patients (36) without testing 2-HEMA in everyone. 94% of allergic patients were women. 37 of the 140 were sensitised by working in the nail industry and 97 were sensitised by wearing acrylic nails. Only six people developed the allergy due to exposure to other sources (surgical glue, adhesive medical appliances and printing ink). The authors recommend that 2-HEMA 2% pet. should be added to the British baseline patch test series and suggest a standardised short series of 15 (meth)acrylate chemicals, which is likely to detect most cases of (meth)acrylate allergy.
Abstract 14262: Cardiotoxicity Associated With Immune Checkpoint Inhibitors: A Single Center Experience
Authors: Nida Waheed, Chintan Shah, Cherokie Boyd, Keith March, Jan Moreb, Yonghui Wu, Yan Gong
Journal: Circulation (2018)

Introduction: Immune checkpoint inhibitors (ICIs) are a major advancement in the treatment of cancer and represent a novel class of antineoplastic agents proven effective against a broad spectrum o...
SAT0280 Rapamycin restores the balance between th17 and regulatory t cells in uspa patients
Authors: F. Jinnan, X. Dan, G. Chong, L. Xiaofeng
Journal: Annals of the Rheumatic Diseases (2018)

<h3>Background</h3> The association of undifferentiated spondyloarthritis (uSpA) with the imbalance of Th17/Treg cells is still unclear. By inhibiting mTOR, rapamycin promotes the proliferation of Treg cells and inhibits the growth of Th17 cells. <h3>Objectives</h3> Therefore, we aimed to investigate the status of Treg and Th17 cells in uSpA patients and explore the therapeutic effect of Rapamycin on uSpA patients with imbalanced of Th17 and Treg cells. <h3>Methods</h3> Two hundred thirty-seven new onset uSpA patients and 93 healthy controls were enrolled. These patients fulfilled ESSG criteria for SpA but did not fulfill the criteria for any established disease of the group. Both absolute numbers and proportions of Treg (CD4 +CD25+Foxp3+T) and Th17 (CD4 +IL-17+T) cells in peripheral blood were analysed by flow cytometry. The 21 new onset Patients with imbalance of Th17/Treg cells were treated with rapamycin at a dose of 0.5 mg twice for a weeks or every 2 days for 6 weeks combined with conventional treatment (salazosulfapyridine 500 mg three times per day; etoricoxib 60 mg once per day or other NSAIDs drugs). <h3>Results</h3> Increase in absolute number and percentage of Th17 (Th17% 1.11±0.66 vs 2.43±1.21, p&lt;0.05; Th17 cells/µl 7.54±4.07 vs 19.54±18.45, p&lt;0.05) and decrease in those of Tregs (Treg% 4.8±1.60 vs 3.35±1.76, p&lt;0.05; Treg cells/µl (33.77±13.67 vs 27.79±28.62, p&lt;0.05) were found in 18.6% (44/237) of patients with uSpA as compared with that of healthy controls. The patients with imbalance of Th17/Treg cells displayed higher BASDAI scores and ESR as compared with other uSpA patients [BASDAI (3.27±1.06 vs 1.13±0.91 P&lt;0.05); ESR (29.27±19.32 vs 21.80±18.34 P&lt;0.05)]. The absolute count of Th17 in 21 patients received rapamycin reduced after 6 weeks (12.35±11.00 vs 6.69±5.54, p&lt;0.05) whereas that of Treg cells showed increase trend but the difference did not reach statistical significance. <h3>Conclusions</h3> Absolute number of Treg decreased and that of Th17 cells increased in the peripheral blood of uSpA patients, suggesting that imbalance of the two subsets contributes to the pathogenesis of uSpA. Rapamycin recovered the balance between Th17 and Treg cells in uSpA patients by reducing Th17 cells. <h3>References</h3> [1] Cruzat V, et al. Undifferentiated spondyloarthritis: recent clinical and therapeutic advances. J. Curr Rheumatol Rep2010Oct;12(5):311–317. [2] da Cruz Lage R, et al. Undifferentiated spondyloarthritis in a heterogeneous Brazilian population: an eight-year follow-up study. J. Rheumatol Int 2014 Jul;34(7):1019–1023. [3] Heather K, et al. Rapamycin inhibits differentiation of Th17 cells and promotes generation of FoxP3+ T regulatory cells. J. Int Immunopharmacol 2007 Dec;15;7(13):1819–1824. [4] Raychaudhuri SP, et al. IL-23/IL-17 axis in spondyloarthritis-bench to bedside. J. Clin Rheumatol 2016 Jun;35(6):1437–1441. <h3>Disclosure of Interest:</h3> None declared
Evaluation of Revised International Staging System for Transplant-Eligible Multiple Myeloma Patients
Authors: Veronica Gonzalez-Calle, Abigail Slack, Susan Luft, Kathryn Pearce, Rhett P. Ketterling, Tania Jain, Sinto Sebastian Chirackal, Craig B. Reeder, Joseph Mikhael, Leif Bergsagel, Pierre Noel, Angela Mayo, James L. Slack, Roberta H. Adams, Gregory Ahmann, Esteban Braggio, Keith Stewart, Scott Van Wier, Rafael Fonseca
Journal: Blood (2016)
Abstract 3543: Long-Term Benefits of Cardiac Rehabilitation in Patients With Incomplete Revascularization: 5-Year Follow-up.
Authors: Romualdo Belardinelli, Francesca Lacalaprice, GianPiero Piccoli, Gianfranco Iacobone, Roberto Piva
Journal: Circulation (2007)

There is evidence that cardiac rehabilitation (CR) determines important benefits in patients with coronary artery disease(CAD). However, it is unclear whether CR may improve the outcome of pts with incomplete revascularization (IR) after PTCA/stenting and/or coronary artery bypass surgery (CABG). From 1/1/2002 to 30/11/2004, we prospectively studied 259 patients with CAD who underwent PTCA after a SCA or CABG in 1(10/7%, respectively), 2(20/19%) and 3 major coronary arteries (70/74%). Patients were randomized into 2 homogeneous groups on the basis of the results of cardiopulmonary exercise stress testing(CPET) performed twice one week apart: a group with a positive CPET for inducible ischemia (P, n=129), and a group with a negative CPET (N, n=130). Patients were further randomized into 2 groups. The intervention group(Group CR) received CR combining exercise training (60%peak VO2, 3 times a week for 8 weeks)+ nutrition counseling+ standard medications (65P+65N, 25% women, mean age 56±8 years), while the control group (Group C) had no CR (65P+64N, 25% women, mean age 58±8 years). On entry and at 8 weeks all patients underwent CPET, brachial artery flow-mediated dilation (BA-FMD) and blood chemistry. Group CR-N had more marked improvements in peak VO2 and FMD than CR-P (P&lt;0.001 for both). However, CPET became negative in 22% post PTCA CR-P patients and 28% post CABG CR-P (P&lt;0.001 vs initial). After 8 weeks, group CR was recommended to continue a home program of exercise training with periodic supervision at the hospital’s gym, while group C was not. At 5 years, both peak VO2 and FMD were significantly higher in CR (P&lt;0.01 vs C) with no differences between CR-P and CR-N. Cardiovascular risk profile (CVRP) was significantly improved in CR (P&lt;0.01 vs C). Cardiac events were significantly lower in CR than C : new acute coronary syndrome (P&lt;0.001); new PCI (P&lt;0.0001); new CABG(P&lt;0.001); hospital readmission: (P&lt;0.0001); cardiac death (P&lt;0.05). Multivariate analysis demonstrated that the lower rate of events in CR was not collinear with changes in CVRP. In conclusion, IHD patients with IR take advantage from CR and maintain a higher functional capacity and a better control of CVRP at 5 years. These benefits were associated with a better outcome.
Phase II trial of trifluridine/tipiracil (TAS-102) in patients with advanced refractory biliary tract cancer (BTC)
Authors: S. Chakrabarti, T. Zemla, F.-S. Ou, B. Fruth, D. Ahn, M.J. Borad, M.L. Hartgers, J. Wessling, R.L. Walkes, S. Alberts, R.R. McWilliams, M.C. Liu, A. Mahipal
Journal: Annals of Oncology (2019)
Comparison of molecular profiles between primary tumour and matched metastasis in non-small cell lung cancer
Authors: A. Kawachi, L. Colmet-Daage, T. Dayris, M. Semeraro, C. Henon, L. Verlingue, N. Dorvault, N. Droin, D. Planchard, A. Hollebecque, C. Massard, V. Thomas de Montpreville, O. Mercier, B. Besse, J.-C. Soria, S. Postel Vinay
Journal: Annals of Oncology (2019)
Benefit of fluorouracil and folinic acid adjuvant in colon cancer elderly patients
Authors: S. Lonardi, M. Stefani, A. Jirillo, C. Ghiotto, L. M. Pasetto, C. Falci, E. Lamberti, S. Monfardini
Journal: Journal of Clinical Oncology (2006)

13564 Background: Retrospective analyses on elderly people enrolled in clinical trials of adjuvant chemotherapy for colon cancer indicated the maintenance of the efficacy in that subset of patients (pts). However, data on the benefit of the routinely used adjuvant treatment in an unselected population of pts aged more than 65 years are few. Methods: All the charts of pts radically operated for colon cancer from 1996–2001 at Medical Oncology, Padua Hospital, were retrospectively analysed. 147 out of 330 pts consecutively treated with fluorouracil (FU)-based chemotherapy was aged 65 years or more at the time of diagnosis. Kaplan-Meyer progression-free-survival (PFS) and overall survival (OS) of stage II and III pts were calculated. Results: Pts characteristics were: males/females: 87/60, median age 71 (range 65–87), ECOG PS 0/1: 124/23, right/left colon primary tumor: 62/85, TNM stage: 24/63/60. 86 out of 147 pts were treated with the following regimen of adjuvant chemotherapy: FU 370 mg/mq + leucovorin (LV) 20 mg/mq day 1–5 q 28 for 6 cycles (Machover regimen, n=69), or FU 500 mg/mq + LV 250 mg/mq weekly × 6 q 56 for 4 cycles (Roswell Park regimen, n=17). Treated pts were staged as follows: TNM stage I/II/III: 1/38/47. No toxic death were observed and only nine of 86 pts (10.4%) stopped the treatment due to acute grade III gastrointestinal toxicity. At a median follow-up of 73.2 months, 19 out of 86 pts (22%) developed cancer recurrence (3-y PFS: 82.2%, 5-y PFS: 80.3%). Seventeen pts (19.7%) died, 13 (15.1%) due to tumor progression, 3 (3.4%) due to acute heart failure, and 1 (1.1%) due to chronic pulmonary disease (3-y OS: 88.8%, 5-y OS: 82.4%). No statistically significant difference in survival was observed comparing pts aged 65–70 (n=41) with pts more than 70 years old (n=45): 5-y OS 84.1% vs 77.8%, respectively (p=2.23, log rank test). A separate survival analysis on stage II pts was performed (n=63). 5 of 38 (13.1) treated pts dead, compared to 9 of 25 (36%) non treated pts; 5-y survival in the two groups were 86.6% and 60.8%, respectively (p= 0.03, log-rank test). Conclusions: The efficacy of adjuvant chemotherapy appears maintained in an unselected population of elderly pts. Surprisingly, our retrospective analysis suggest that even stage II pts may benefit of a fluorouracil-based well tolerated chemotherapy. No significant financial relationships to disclose.
Real-time artificial intelligence for detection of upper gastrointestinal cancer by endoscopy: a multicentre, case-control, diagnostic study
Authors: Huiyan Luo, Guoliang Xu, Chaofeng Li, Longjun He, Linna Luo, Zixian Wang, Bingzhong Jing, Yishu Deng, Ying Jin, Yin Li, Bin Li, Wencheng Tan, Caisheng He, Sharvesh Raj Seeruttun, Qiubao Wu, Jun Huang, De-wang Huang, Bin Chen, Shao-bin Lin, Qin-ming Chen, Chu-ming Yuan, Hai-xin Chen, Heng-ying Pu, Feng Zhou, Yun He, Rui-hua Xu
Journal: The Lancet Oncology (2019)
Biomarker status as a mediator of age-related overall survival (OS) in advanced non-small cell lung cancer (aNSCLC)
Authors: A.B. Cohen, B D A P Neri, B.J.S. Adamson, C.M. Scanlon, C. Gross, N.J. Meropol, R.A. Miksad
Journal: Annals of Oncology (2019)
Genetic variants in the one-carbon metabolism pathway to predict outcome in patients with metastatic colorectal cancer (mCRC): Data from TRIBE and FIRE-3 phase III trials
Authors: A. Puccini, F. Loupakis, S. Stintzing, S. Cao, J. Millstein, F. Battaglin, M.D. Berger, R. Togunaka, M. Naseem, W. Zhang, C. Cremolini, A. Falcone, V. Heinemann, H.J. Lenz
Journal: Annals of Oncology (2019)