tbuckley/cabot-search huggingface dataset:
The Evolution of Insulin and How it Informs Therapy and Treatment Choices
Authors: Irl B Hirsch, Rattan Juneja, John M Beals, Caryl J Antalis, Eugene E Wright
Journal: Endocrine Reviews (2020)

Insulin has been available for the treatment of diabetes for almost a century, and the variety of insulin choices today represents many years of discovery and innovation. Insulin has gone from poorly defined extracts of animal pancreata to pure and precisely controlled formulations that can be prescribed and administered with high accuracy and predictability of action. Modifications of the insulin formulation and of the insulin molecule itself have made it possible to approximate the natural endogenous insulin response. Insulin and insulin formulations had to be designed to produce either a constant low basal level of insulin or the spikes of insulin released in response to meals. We discuss how the biochemical properties of endogenous insulin were exploited to either shorten or extend the time-action profiles of injectable insulins by varying the pharmacokinetics (time for appearance of insulin in the blood after injection) and pharmacodynamics (time-dependent changes in blood sugar after injection). This has resulted in rapid-acting, short-acting, intermediate-acting, and long-acting insulins, as well as mixtures and concentrated formulations. An understanding of how various insulins and formulations were designed to solve the challenges of insulin replacement will assist clinicians in meeting the needs of their individual patients.
Effect of Drug Treatment for Lymphoma on Male Reproductive Capacity
Authors: RICHARD J. SHERINS
Journal: Annals of Internal Medicine (1973)

Reproductive function was evaluated in 16 men who had been treated with a combination of nitrogen mustard, vincristine, procarbazine, and prednisone (MOPP); a similar combination, with methotrexate instead of procarbazine (MOMP); cyclophosphamide, vincristine, and prednisone (CVP); or cyclophosphamide for lymphoma, were in remission, and had received no therapy for 6 months to 7 years. Although libido and potency were normal in all patients, 10 men were azoospermic, and testicular biopsy showed complete absence of germ cells; 2 men showed minimal evidence of spermatogenesis; and 4 men, in remission for 2 to 7 years, showed complete spermatogenesis at the time of their evaluation. Within each treatment group the men with evidence of normal germinal tissue were those who had been in remission longest for that group. These data suggest that spermatogenesis may return after extensive chemotherapy but that this is more likely to occur more than 2 years after drug treatment.
EUS DIAGNOSIS AND NATURAL COURSE OF SUBEPITHELIAL TUMORS IN THE UPPER GI TRACT - DATA FROM A TERTIARY REFERRAL CENTER
Authors: J Bartha, W Schorr, D Amissah, J Schedel, O Pech
Journal: Endoscopy (2020)

Aims Subepithelial tumors (SET) are found in 1-2% of upper endoscopies. Usually, endoscopic ultrasound (EUS) is performed as the next diagnostic step in order to determine the layer from which the SET arises and to describe the EUS features. Data from large tertiary centers on the diagnostic value of EUS and the natural course of SET are scarce.
Respiratory Parameters in Patients With COVID-19 After Using Noninvasive Ventilation in the Prone Position Outside the Intensive Care Unit
Authors: Chiara Sartini, Moreno Tresoldi, Paolo Scarpellini, Andrea Tettamanti, Francesco Carcò, Giovanni Landoni, Alberto Zangrillo
Journal: JAMA (2020)

Xavier Elharrar, MD; Youssef Trigui, MD; Anne-Marie Dols, MD; François Touchon, MD; Stéphanie Martinez, MD; Eloi Prud'homme, MD; Laurent Papazian, MD, PhD
A COST EFFECTIVENESS ANALYSIS (CEA) COMPARING THE PURE-VU SYSTEM TO STANDARD COLONOSCOPY IN AVERAGE AND HIGH-RISK PATIENTS PRESENTING WITH INADEQUATELY PREPPED COLONS
Authors: I Gralnek, J Voigt, S Nussbaum
Journal: Endoscopy (2020)

Aims To perform a CEA examining impact of a new technology (Pure-Vu System) for cleaning inadequately prepped colons during colonoscopy.
PLEASE, take a deep breath
Authors: José M. Porcel
Journal: European Respiratory Journal (2020)

Dyspnoea, a subjective experience of breathing discomfort, is a debilitating symptom which impacts quality of life in patients with pleural effusions. It consists of a number of perceptions, including a sense of work/effort, tightness in the chest and air hunger. Dyspnoea affects up to 80% of patients with malignant pleurisy [1–3], and an even higher percentage of those with heart failure-associated effusions [4]. Pleural effusions can have a large impact, not only on breathing and quality of life [5], but also on sleep [6] and exercise capacity [7]. Combining history taking and a bedside ultrasound may be the best way to predict symptomatic relief after thoracentesis in patients with pleural effusions <http://bit.ly/2xwTJ9z>
DIFFERENCES IN BOWEL PREPARATION QUALITY BETWEEN IN- AND OUTPATIENTS UNDERGOING SCREENING COLONOSCOPY
Authors: C Schweitzer, D Penz, A Ferlitsch
Journal: Endoscopy (2020)

Aims Adequate bowel preparation is a key factor for high quality colonoscopy. Patients undergoing outpatient colonoscopy assess bowel preparation without enhanced instructions or help, while nurses provide structured education, follow the administration of colonoscopy preparation in hospitalized patients, as these patients are likely to be older and have significant comorbities. Therefore, aim of this study was to analyze the effect of enhanced instructions and surveillance for inpatients on the quality of bowel preparation for patients undergoing screening colonoscopy.
The UK needs a Health and Care Workers Covenant
Authors: Stephen T Green, Fiona A M Green
Journal: BMJ (2020)

Abbasi mentions the vast number of problems that covid-19 has uncovered.1 To which we might add the very thing that ensures we have a functioning health service—as Hiam and colleagues say, the NHS is “run on the goodwill of its staff.”2

It has long been thus. This goodwill was described in 2015 as “a one-way street.”3 Despite its importance, only very occasionally has this reality been acknowledged publicly by politicians.

By way of comparison, we should look …
Cas9 activates the p53 pathway and selects for p53-inactivating mutations
Authors: Oana M. Enache, Veronica Rendo, Mai Abdusamad, Daniel Lam, Desiree Davison, Sangita Pal, Naomi Currimjee, Julian Hess, Sasha Pantel, Anwesha Nag, Aaron R. Thorner, John G. Doench, Francisca Vazquez, Rameen Beroukhim, Todd R. Golub, Uri Ben-David
Journal: Nature Genetics (2020)
CLINICAL OUTCOME OF ERCP IN HULL UNIVERSITY TEACHING HOSPITALS NHS TRUST
Authors: M Ishtiaq, G Abouda
Journal: Endoscopy (2020)

Aims Endoscopic retrograde cholangiopancreatography (ERCP) is predominantly performed as therapeutic procedure and carries substantial risk of complications when compared to other endoscopic procedures. British Society of Gastroenterology(BSG) in conjunction with Joint Advisory Group(JAG) for Gastrointestinal Endoscopy has recommended quality and safety guidelines for ERCP procedure. The purpose of audit was to compare our local ERCP practice to nationally agreed.
PERFORMANCE OF RUTGEERTS SCORE FOR RECURRENCE OF CROHN’S DISEASE IN PATIENTS WITH ILEOCECAL RESECTION
Authors: M Borahma, M Mahmoudi, N Lagdali, C Berhili, I Benelbarhdadi, FZ Ajana
Journal: Endoscopy (2020)

Aims Our study aimed to assess the risk of recurrence after an ileocecal resection and to appreciate the performance of Rutgeerts score on the management of operated Crohn´s disease.
THE MYOCARDIAL CREATINE-PHOSPHATE ATP RATIO, MEASURED BY 31P-MR SPECTROSCOPY, AS A PREDICTOR OF MORTALITY IN PATIENTS WITH DILATED CARDIOMYOPATHY
Authors: S Neubauer, M Horn, M Godde, K Harre, T Pabst, J B Newell, W Peters, D Hahn, G Ertl, K Kochsiek
Journal: Circulation (1995)
Endoscopic submucosal dissection by transnasal endoscope for esophageal cancer with pharyngoesophageal anastomotic stricture after total pharyngo-laryngo-esophagectomy
Authors: Yoshiyasu Kitagawa, Takuto Suzuki, Kentaro Nakamura, Rino Nankinzan, Taketo Yamaguchi
Journal: Endoscopy (2020)

Patients with squamous cell carcinoma (SCC) of the head and neck often develop secondary esophageal carcinomas. We describe a successful case of endoscopic submucosal dissection (ESD) using a transnasal endoscope to treat a patient with esophageal cancer with a pharyngoesophageal anastomotic stricture after total pharyngo-laryngo-esophagectomy (TPLE).
UPPER IATROGENIC ESOPHAGEAL PERFORATION SUCCESSFULLY TREATED BY THE “COVER” TECHNIQUE WITH ANCHORING SUTURE: A MINI-INVASIVE SOLUTION IN A “TROUBLESOME” LOCATION
Authors: A Granata, M Amata, D Ligresti, A Bertani, L De Monte, A Martino, M Traina
Journal: Endoscopy (2020)

71-year-old woman was referred to our Institute for metachronous neoplastic nodule in the upper-right pulmonary lobe. Following two complex selective orotracheal intubations, the patient underwent complete VATS right upper lobectomy. After 48-hours, patient developed dysphagia. Endoscopy showed a 40-mm longitudinal esophageal laceration 2 cm under the cricoid ring. After the failure of subsequent surgical and endoscopic revisions with clips, FC-SEMS placement with anchoring single-sutures using the OverStitch Endoscopic Suturing System was effectively performed although the too-close location to cricoid ring. After 2 months, stent was removed using a flexiblefully-rotatable endoscopic scissors (Ensizor Flex). At 6-month follow-up, the patient remained asymptomatic.
ENDOSCOPIC TREATMENT FOR SIGMOID VOLVULUS: SINGLE-CENTER RETROSPECTIVE ANALYSIS
Authors: E Dantas, M Coelho, C Sequeira, I Santos, C Teixeira, C Martins, C Cardoso, J Mangualde, R Freire, É Gamito, AL Alves, I Cremers, AP Oliveira
Journal: Endoscopy (2020)

Aims Sigmoid volvulus is one of the most common causes of colonic obstruction, caused by the rotation of the sigmoid colon around its meso axis. Diagnosis is based on clinical and radiological elements, either by X-rays or computed tomography (CT). First-line emergency therapy relies on endoscopic treatment (ET) of the volvulus, consisting in the detorsion of the affected loop, associated with colonic decompression.
Clinical Utility of Routine Alcohol Screening in Large Health Care Systems for Addressing a Leading Epidemic in the US
Authors: Emily C. Williams
Journal: JAMA Network Open (2020)

Stacy A. Sterling, DrPH, MSW; Vanessa A. Palzes, MPH; Yun Lu, MPH; Andrea H. Kline-Simon, MS; Sujaya Parthasarathy, PhD; Thekla Ross, PsyD; Joseph Elson, MD; Constance Weisner, DrPH, MSW; Clara Maxim; Felicia W. Chi, MPH
PERCUTANEOUS ENDOSCOPIC GASTROSTOMY IN PATIENTS WITH ACUTE STROKE. EARLY OR DELAYED PLACEMENT?
Authors: E Orfanoudaki, I Drygiannakis, A Augoustaki, E Stamatopoulos, S Ioannidis, P Mitsias, M Koulentaki
Journal: Endoscopy (2020)

Aims Percutaneous endoscopic gastrostomy (PEG) is indicated for patients with acute stroke and anticipated prolonged dysphagia for more than 28 days. The most favorable time for PEG placement is controversial. We aim to present our experience on the management of patients with acute stroke and dysphagia.
OUTCOMES OF PRECUT NEEDLE KNIFE FISTULOTOMY BASED ON THE ENDOSCOPIC MORPHOLOGY OF THE AMPULLA OF VATER AND OF THE SIZE OF BILE DUCT
Authors: J Fernandes, M Moreira, G Alexandrino, T Araújo, D Horta, L Lourenço, J Canena, L Lopes
Journal: Endoscopy (2020)

Aims Previous studies have suggested that the success and complications of precut needle knife fistulotomy (NKF) for achieving biliary access is largely dependent of the endoscopic morphology of the ampulla of Vater and also of the bile duct size. However, no study has addressed this topic. This study evaluated the outcomes of NKF on the basis of the morphology of the major papilla and of the size of the bile duct.
PLASMABLASTIC PLASMACYTOMA OF THE RECTUM AND ANAL CANAL IN PATIENT WITH ULCERATIVE COLITIS
Authors: Katarina Jankovic, Sanja Rajic, Milica Stojkovic Lalosevic, Sanja Dragasevic, Snezana Lukic, Srdjan Djuranovic, Ivan Jovanovic
Journal: Endoscopy (2020)

Aims Plasma cell tumor is a B-cell line immunoproliferative monoclonal disease. It rarely occurs in the gastrointestinal tract (GI). Our aim was to present a case of a patient with a prior history of ulcerative colitis (UC). Given its clinical presentation upon admission, the patient could easily be mistaken for disease relapse indicating the need for endoscopy along with further evaluation to establish a correct diagnosis and therefore appropriate treatment.
THE ELIMINATION OF THE NOSTRUM TRAFFIC, AN EVIDENT DUTY OF AMERICAN PHYSICIANS.
Authors: M. I. WILBERT
Journal: JAMA (1906)

What is a nostrum? Why should nostrums be eliminated? Why should physicians be interested in their elimination? As an answer to the last and certainly the most directly interesting of these three questions it may be pointed out that, apart from the duties and obligations imposed on physicians, by the traditional oath of Hippocrates, the practice of medicine, in every state, is hedged about and protected by laws that are designed to prevent the ignorant and the incompetent from imposing on the people of the commonwealth, and also, in a measure at least, are designed to protect regularly licensed members of the medical profession from imposition and unnecessary competition in the practice of their science or art. The members of the medical profession, on the other hand, in thus seeking and accepting the protection secured to them under these several statutory enactments, are expected to guard and to protect the
EPIDEMIOLOGY OF HELICOBACTER PYLORI FOR PATIENTS WITH GASTRIC DISEASES AND ASYMPTOMATIC POPULATION IN MOROCCO
Authors: I Essaidi, H Boura, G Bounder, R Jouimy, A Majd, H Jouhadi, H Benomar, K Zerouali, F Maachi
Journal: Endoscopy (2020)

Aims Helicobacter pylori infection is recognized as a worldwide problem, mainly in developing countries where infection reaches 80% of the population. H.pylori is associated with various gastric diseases, mainly, many benign, premalignant, and malignant lesions of the gastric mucosa. The aim of our study was to determine the prevalence of H.pylori infection in asymptomatic population and gastric disease’s patients.
Quantification of Femoral Adipose Tissue Provides Novel Mechanistic Insights Into the "Obesity Paradox": a Translational Approach
Authors: A S Antonopoulos, M Margaritis, L Herdman, P Coutinho, C Psarros, J Digby, G Krasopoulos, M Petrou, K M Channon, C Antoniades
Journal: Circulation (2014)
EUS-GUIDED CHOLECYSTOGASTROSTOMY AS A PALIATIVE TREATMENT OF MALIGNANT BILIARY OBSTRUCTION
Authors: P Vitek, J Kuchar, IM Kajzrlikova, P Klvana, H Hlavikova, J Chalupa
Journal: Endoscopy (2020)

73-year-old man with inoperable pancreatic cancer with two liver metastases was admited for obstructive jaundice and biliary dilation on abdominal CT. Retrograde drainage via ERCP failed due to duodenal stenosis even after baloon dilation. EUS-guided drainage was indicated. Anatomical situation was not suitable for hepaticogastrostomy or choledochoduodenostomy, therefore cholecystogastrostomy with LAMS (15 mm width, 10 mm lenght) was performed. Decrease of bilirubin level after procedure was very quick. Concurrent gastric outlet obstruction was treated with duodenal stent (23 mm width, 120 mm length). Paliative oncological treatment followed.
Prospective patient stratification into robust cancer-cell intrinsic subtypes from colorectal cancer biopsies
Authors: M Alderdice, S D Richman, S Gollins, P Stewart, C Hurt, R Adams, A M McCorry, A Roddy, D Vimalachandran, C Isella, E Medico, T Maughan, D G McArt, M Lawler, P D Dunne
Journal: Cancer Research (2018)
CHANGES IN PERFORMANCE OF SMALL BOWEL CAPSULE ENDOSCOPY BASED ON NATIONWIDE DATA FROM A KOREAN CAPSULE ENDOSCOPY REGISTRY
Authors: SH Kim, YJ Lim, JS Park, K-N Shim, D-H Yang, J Chun, JS Kim, HS Lee, HJ Chun
Journal: Endoscopy (2020)

Aims Capsule endoscopy (CE) is widely used for the diagnosis of small bowel diseases. The clinical performance and complications of small bowel CE, including completion rate, capsule retention rate, and indications, have been previously described in Korea. This study aimed at estimating the recent changes in clinical performance and complications of small bowel CE based on 17-year data from a Korean capsule endoscopy registry.
DOES DOUBLE HIGH LEVEL DISINFECTION FOR DUODENOSCOPES ADD ANY VALUE? A SYSTEMATIC REVIEW AND META ANALYSIS
Authors: O Elbahr, A Saleh, AA Aziz, S Awad, F Khalil, S Afiffy, A Kamal, A Alsebaey, G Badra
Journal: Endoscopy (2020)

Aims Duodenoscopes emerging infection especially drug resistant bacteria considered a major concern nowadays. Different approaches were tried to overcome this problem, like double high level disinfection procedure.Our aim was to perform a systematic review and meta analysis to evaluate risk difference for positive cultures from duodenoscopes between double high level disinfection (dHLD) and single high level disinfection (sHLD).
Post-transplantation cyclophosphamide GvHD prophylaxis after hematopoietic stem cell transplantation from 9/10 or 10/10 HLA-matched unrelated donors for acute leukemia
Authors: Francesca Lorentino, Myriam Labopin, Fabio Ciceri, Luca Vago, Katharina Fleischhauer, Boris Afanasyev, Nicolaus Kröger, Jan J. Cornelissen, Montserrat Lovira, Ellen Meijer, Antonin Vitek, Ahmet Elmaagacli, Didier Blaise, Annalisa Ruggeri, Christian Chabannon, Arnon Nagler, Mohamad Mohty
Journal: Leukemia (2020)
HISINVIA: A HYBRID SOLUTION FOR COLONIC POLYP HISTOLOGY PREDICTION IN WHITE LIGHT COLONOSCOPY IMAGES COMBINING ARTIFICIAL INTELLIGENCE AND CLINICAL INFORMATION
Authors: A García-Rodríguez, Y Tudela, FJ Sánchez, H Córdova, R Garcés-Durán, M Cuatrecasas, M Pellisé, S Carballal, L Moreira, L Rivero, J Llach, J Bernal, G Fernández-Esparrach
Journal: Endoscopy (2020)

Aims In-vivo histology prediction is the cornerstone to improve the cost-efficiency of colonoscopy procedures. Artificial Intelligence (AI), specifically via Deep learning (DL) systems, can help physicians during colonoscopy in this task. However, its efficiency has not yet reached the levels of performance necessary to be used in the exploration room. In order to improve that, we propose a hybrid approach (HISINVIA) that combines DL methods with polyps characteristics indicated by doctors.
Mortality impacts of the coronavirus disease (COVID-19) outbreak by sex and age: rapid mortality surveillance system, Italy, 1 February to 18 April 2020
Authors: Paola Michelozzi, Francesca de’Donato, Matteo Scortichini, Manuela De Sario, Fiammetta Noccioli, Pasqualino Rossi, Marina Davoli
Journal: Eurosurveillance (2020)

Data from the rapid mortality surveillance system in 19 major Italian cities were used to carry out a timely assessment of the health impact of the COVID-19 epidemic. By 18 April, a + 45% excess in mortality was observed, with a higher impact in the north of the country (+ 76%). The excess was greatest among men, with an increasing trend by age. Surveillance data can be used to evaluate the lockdown and re-opening phases.
AUDIT OF COLONOSCOPIES CARRIED OUT FOR THE INDICATION OF ABNORMAL RADIOLOGICAL IMAGING OVER A 4 YEAR PERIOD IN A LARGE TERTIARY REFERRAL CENTRE
Authors: R Corcoran, S O’Reilly, S Hough, K Hartery, S McKiernan, D Kevans, F MacCarthy
Journal: Endoscopy (2020)

Aims A frequent indication for colonoscopy referral is abnormal findings on cross-sectional imaging or PET. Colonic abnormalities may also be incidentally detected in patients undergoing imaging for other reasons. Our aim was to determine the yield of endoscopy in the investigation of intestinal abnormalities detected on cross-sectional imaging.
INCIDENCE OF COLORECTAL NEOPLASIA AMONG YOUNG PATIENTS WITH LYNCH SYNDROME IN CORRELATION WITH THE TYPE OF MUTATION: RESULTS OF THE LARGEST PARIS AREA COHORT
Authors: E Coffin, C Lekhal, G Perrod, E Samaha, E Perez Cuadrado, C Colas, M Dhooge, J Netter-Cotti, O Caron, V Cusin, G Perkins, A Zaanan, B Buecher, J Bellanger, Y Parc, D Malka, S Chaussade, P Laurent Puig, R Benamouzig, C Cellier
Journal: Endoscopy (2020)

Aims International guidelines recommend colorectal cancer (CRC) screening in patients with Lynch Syndrome, starting from 20-25 years-old except for MSH6 and PMS2 where the screening should start at 35 years-old.
SURVEILLANCE WITH CHROMOENDOSCOPY TO DETECT NEW DYSPLASIA IN INFLAMMATORY BOWEL DISEASE
Authors: CV Lucas, RQ Castro, RP Fernández, RG Nuñez, LA Vega, VC Lopez, LV Ayala, MS Ausin
Journal: Endoscopy (2020)

Aims We aimed to assess our endoscopic results from follow-up chromoendoscopy in Inflammatory Bowel Disease (IBD) patients with previous diagnose of dysplasia.
EFFICACY OF UNDERWATER ENDOSCOPIC MUCOSAL RESECTION FOR THE TREATMENT OF LARGE COMPLEX COLORECTAL LESIONS: A RANDOMIZED AND MULTICENTER CONTROL TRIAL
Authors: J Rodríguez Sánchez, D Coto Ugarte, HIU Koeklin, MP Ulquiza, JC Marín Gabriel, J Aranda, FR Pons, MA Álvarez González, L Hernández, R Carreño Macian, J Santiago, O Patrón, AH de Tejada, O Nogales, M Rodríguez Téllez, E Valdivieso Cortazar, A Álvarez, E Albéniz Albizu
Journal: Endoscopy (2020)

Aims The efficacy of U-EMR has been tested in small and médium size colorectal lesions. However there are not comparative studies focussed on assessing its suitability for the treatment of complex colorectal lesions (> 2 cm in size or scared).
COVID‐19 Clinical trials: Quality matters more than quantity
Authors: Sergio Bonini, Giuseppe Maltese
Journal: Allergy (2020)

Despite the ferment aroused in the scientific community by the COVID-19 outbreak and the over 11,000 papers listed in PubMed, published evidence on safe and effective drugs has not progressed yet at the same speed of the pandemic. However, clinical research is rapidly progressing, as shown by the hundreds of registered clinical trials on candidate drugs for COVID-19. Unfortunately, information on protocols of individual studies differs from registry to registry. Furthermore, study designs, criteria for stratification of patients and choice of outcomes are quite heterogeneous. All this makes data sharing and secondary analysis difficult. At last, small single centre studies and the use of drugs on a compassionate basis should be replaced by highly powered, multi-centre, multi-arm clinical trials, in order to provide the required evidence of safety and efficacy of novel or repurposed candidate drugs. Hopefully, the efforts of clinical researchers in the fight against the SARS Cov-2 will result into the identification of effective treatments. To make this possible, clinical research should be oriented by guidelines for more harmonized high-quality studies and by a united commitment of the scientific community to share personal knowledge and data. Allergists and clinical immunologists should have a leading role in this unprecedent challenge.
ENDOSCOPIC SUBMUCOSAL DISSECTION (ESD): EXPERIENCE FROM A TERTIARY REFERRAL CENTRE IN LONDON REGARDING SALINE-IMMERSION THERAPEUTIC ENDOSCOPY (SITE) COMBINED WITH THE POCKET-CREATION METHOD (PCM)
Authors: EJ Despott, C Coppo, N Lazaridis, D Costa, R Raymond, A Skamnelos, N Koukias, T Luong, J Watkins, A Murino
Journal: Endoscopy (2020)

Aims Endoscopic submucosal dissection (ESD) is a potentially curative, minimally-invasive alternative to major surgery for the endoscopic management of superficial gastric and colorectal neoplasms. Due to its several advantages pocket-creation method (PCM) appears to simplify ESD. Since 2017, we have combined PCM with saline-immersion therapeutic endoscopy (SITE), as this could improve view quality (through refractive magnification, and minimal lense fogging) and lesion lifting (through buoyancy).
DEVELOPMENT AND INITIAL EVALUATION OF THE VALID-CLASSIFICATION FOR PREDICTION OF COLORECTAL POLYP HISTOLOGY - A MULTICENTER INTERNATIONAL TRIAL
Authors: H Neumann, PJ Rosón, L Negreanu, MA De Lusong, H Hohn, HN Sen, BS Ravindra
Journal: Endoscopy (2020)

Aims The recently introduced VIST chromoendoscopy technique allows for detailed analysis of surface and vascular pattern morphology. The study aimed to create a new and unique classification for differentiating colorectal polyps using the VIST technology. We additionally aimed to assess the new classification’s interobserver concordance, and evaluate its accuracy in predicting colorectal polyp histology.