tbuckley/cabot-search huggingface dataset:
Outcomes of beta-lactam antibiotic test dose procedures for patients with reported beta-lactam allergy performed in a large US healthcare system
Authors: Kimberly G. Blumenthal, Anna R. Wolfson, Joyce T. Hsu, Erica S. Shenoy, Yu Li, Jesse M. Schwartz, Victoria A. Carballo, Barbara B. Lambl, David N. Berkowitz, Kathleen A. Marquis, Ramy Elshaboury, Alana Gruszecki, Paige G. Wickner
Journal: Journal of Allergy and Clinical Immunology (2019)
Evidence of Long-Lasting Anti-CD19 Activity of Engrafted CD19 Chimeric Antigen Receptor Modified T Cells in a Phase I Study Targeting Pediatrics with Acute Lymphoblastic Leukemia
Authors: Futian Ma, Jin-Yuan Ho, Huan Du, Fan Xuan, Xiaoli Wu, Ying Liu, Yizhuo Wang, Jianmin Luo, Jianqiang Li
Journal: Blood (2018)
Clarification of Reporting of Outcome Measures and Protocol Deviations in Report of a Randomized Clinical Trial
Authors: Ian William Skinner, Aidan G. Cashin, Matthew K. Bagg
Journal: JAMA Neurology (2019)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Neurology HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Neurology journal
Medical misinformation: vet the message!
Authors: Joseph A Hill, Stefan Agewall, Adrian Baranchuk, George W Booz, Jeffrey S Borer, Paolo G Camici, Peng-Sheng Chen, Anna F Dominiczak, Çetin Erol, Cindy L Grines, Robert Gropler, Tomasz J Guzik, Markus K Heinemann, Ami E Iskandrian, Bradley P Knight, Barry London, Thomas F Lüscher, Marco Metra, Kiran Musunuru, Brahmajee K Nallamothu, Andrea Natale, Sanjeev Saksena, Michael H Picard, Sunil V Rao, Willem J Remme, Robert S Rosenson, Nancy K Sweitzer, Adam Timmis, Christiaan Vrints
Journal: Cardiovascular Research (2019)
Long-Term Follow up of Front-Line Therapy with Ofatumumab, High Dose Methylprednisolone and Lenalidomide (HiLO trial) for Treatment-Naïve Chronic Lymphocytic Leukemia
Authors: Ariel Felipe Grajales-Cruz, Julio C. Chavez, Elyce P. Turba, Lisa Nodzon, Francisco Perez Leal, Jose Sandoval-Sus, Rami S. Komrokji, Frederick L. Locke, Mohamed A Kharfan-Dabaja, Bijal D. Shah, Lubomir Sokol, Celeste M. Bello, Javier Pinilla Ibarz
Journal: Blood (2018)
Proof of Concept for an Adaptive Treatment Strategy to Prevent Failures in Internet-Delivered CBT: A Single-Blind Randomized Clinical Trial With Insomnia Patients
Authors: Erik Forsell, Susanna Jernelöv, Kerstin Blom, Martin Kraepelien, Cecilia Svanborg, Gerhard Andersson, Nils Lindefors, Viktor Kaldo
Journal: American Journal of Psychiatry (2019)

This study aimed to demonstrate proof of concept for an adaptive treatment strategy in Internet-delivered cognitive-behavioral therapy (ICBT), where risk of treatment failure is assessed early in treatment and treatment for at-risk patients is adapted to prevent treatment failure.A semiautomated algorithm assessed risk of treatment failure early in treatment in 251 patients undergoing ICBT for insomnia with therapist guidance. At-risk patients were randomly assigned to continue standard ICBT or to receive adapted ICBT. The primary outcome was self-rated insomnia symptoms using the Insomnia Severity Index in a linear mixed-effects model. The main secondary outcome was treatment failure (having neither responded nor remitted at the posttreatment assessment).A total of 102 patients were classified as at risk and randomly assigned to receive adapted ICBT (N=51) or standard ICBT (N=51); 149 patients were classified as not at risk. Patients not at risk had significantly greater score reductions on the Insomnia Severity Index than at-risk patients given standard ICBT. Adapted ICBT for at-risk patients was significantly more successful in reducing symptoms compared with standard ICBT, and it decreased the risk of failing treatment (odds ratio=0.33). At-risk patients receiving adapted ICBT were not more likely to experience treatment failure than those not at risk (odds ratio=0.51), though they were less likely to experience remission. Adapted treatment required, on average, 14 more minutes of therapist-patient time per remaining week.An adaptive treatment strategy can increase treatment effects for at-risk patients and reduce the number of failed treatments. Future studies should improve accuracy in classification algorithms and identify key factors that boost the effect of adapted treatments.
Abstract 14797: Relationship of Carotid Intima-media Thickness With Incident Heart Failure With Reduced versus Preserved Ejection Fraction: The Multi-Ethnic Study of Atherosclerosis (MESA)
Authors: Amer I Aladin, Elsayed Z Soliman, Dalane W Kitzman, Zeina Dardari, Shereen H Rasool, Joseph Yeboah, Mahmoud Al Rifai, Matthew J Budoff, Bruce M Psaty, Pamela Ouyang, Joseph F Polak, Roger S Blumenthal, John W McEvoy, Sanjay K Gandhi, David M Herrington
Journal: Circulation (2017)

Introduction: Carotid intima-media thickness (cIMT) is associated with heart failure (HF) in previous studies, but it is unknown whether the association of cIMT differs between HF with reduced (HFrEF) versus preserved ejection fraction (HFpEF). Hypothesis: cIMT is associated with increased risk of HFrEF and HFpEF. Methods: We studied 6726 participants (mean age 62 ± 10 yrs., 47% male, 38% white) from the Multi-Ethnic Study of Atherosclerosis (MESA) with cIMT measurements at baseline. An adjudication committee ascertained HF events for a mean follow-up of 12.1 yrs. We classified HF events as HFrEF (EF <50%) or HFpEF (EF ≥ 50%) at the time of diagnosis. Cox proportional hazard regression was used to compute hazard ratios (HR), and 95% confidence intervals (CI) for the association between the IMT Z-score (measured maximum IMT of IC and CC sites as the mean of the maximum IMT of the near and far walls of right and left sides), and incident HFrEF or HFpEF. Models were adjusted for covariates and interim corona...
Role of imaging in low-grade cutaneous B-cell lymphoma presenting in the skin
Authors: Meenal K. Kheterpal, Julia Dai, Shamir Geller, Melissa Pulitzer, Andy Ni, Patricia L. Myskowski, Alison Moskowitz, Jinah Kim, Eric K. Hong, Sophia Fong, Richard T. Hoppe, Youn H. Kim, Steven M. Horwitz
Journal: Journal of the American Academy of Dermatology (2019)
Abstract 18629: Modulating Heparan Sulfation and Disaccharide Content Significantly Blocks Early Rejection in Mouse Renal Transplants
Authors: Sriram Ambadapadi, Dara N Wakefield, Hao Chen, Mee Y Bartee, Parastoo Azadi, Stephanie Archer-Hartmann, Jordan R Yaron, Donghang Zheng, Kevin D Ergle, Liqiang Zhang, Chad R Borges, Byron P Croker, Kenneth H Rand, Jeffrey D Esko, William L Clapp, Alexandra Lucas
Journal: Circulation (2017)

Introduction: The endothelial glycocalyx alters immune reactions and glycosaminoglycans (GAGs) in the glycocalyx bind chemokines that attract immune cell invasion. Prior work has implicated heparan sulfation and disaccharide content in acute rejection after transplantation. Myxomavirus encodes a broad-spectrum chemokine modulating protein, M-T7 that reduces aortic allograft vasculopathy and renal allograft rejection in rodent models. We investigated the effects of conditional endothelial deficiency of the primary heparin sulfate modifying enzyme (N-deacetylase-N-sulfotransferase-1, Ndst1-/-) on renal allograft transplants. Methods: Donor kidneys from C57Bl/6J mice (WT, Ndst1+/+) or Ndst1-/- mice were transplanted into Balb/C mice with normal Ndst1 expression. Rejection was assessed in recipients of WT and Ndst1-/- donor allografts, and compared to M-T7 treatment in WT kidney transplants at 10-day follow up. Results: Recipients of Ndst1-/- donor organs treated with saline (N=9 mice; P<0.012) and WT donor o...
Abstract P037: Epigenetic Markers of Cardiovascular Health Trajectories and Coronary Artery Calcification in the Coronary Artery Risk Development in Young Adults (CARDIA) Study
Authors: Lifang Hou, Yinan Zheng, Norrina B. Allen, Drew Nannini, Zhou Zhang, Lei Liu, Wei Zhang, Amy E. Krefman, Myriam Fornage, Hongyan Ning, Cora E. Lewis, Pamela Schreiner, Stephen Sidney, James Shikany, Kiang Liu, Donald M. Lloyd-Jones, Philip Greenland
Journal: Circulation (2017)

Background: Trajectory of AHA’s cardiovascular health (CVH) through young adulthood are associated with subclinical CVD. The human epigenome is modifiable by lifestyle and environmental factors and may be an important mechanism of CVH outcomes. We sought to determine associations of epigenetic markers with CVH trajectories and with coronary artery calcification (CAC) through young adulthood. Methods: Among CARDIA ppts, we performed methylome analysis at follow up year (Y) 15 and Y20 using Illumina Methylation EPIC array (~850K CpG loci). We compared methylome between those with optimal CVH at baseline and remained stable (optimal-stable, n=645) and individuals with baseline optimal but declining CVH during follow up (n=100) to identify methylomic biomarkers of CVH trajectories. Differentially methylated CpGs were further examined in association with incident CAC risk at Y25 (n=745), and for their potential mediating role in CVH-associated CAC risk. Results: In 1,087 CARDIA ppts (mean age=25 at baseline), we identified 25 hypermethylated CpGs (18 at Y15, 13 at Y20, including 6 seen at both Y15 and Y20) significantly associated with optimal-stable CVH trajectories. The 6 common CpGs were stable (mean ICC = 0.66) whereas the remaining 19 CpGs were dynamic (mean ICC = 0.39) over a 5-year interval. Hypermethylation of 6 stable CpGs was associated with a decreased risk of having future CAC incidence ( Table 1 ). Hypermethylation of 10 (out of 19) dynamic CpGs at Y20 was associated with a decreased risk for incident CAC while the associations was less pronounced at Y15. Mediation analyses showed that hypermethylation of these 16 CpGs at Y15 and Y20 contributed 15% and 23% reduction in the CVH-associated relative risks (RRs) of CAC incidence at Y25. Conclusion: We observed distinct methylomic patterns in young adulthood with stable optimal CVH trajectories relative to those with declining CVH. CVH associated methylomic marks may predict CAC incidence and potentially mediate the associations of CVH trajectories with incident CAC risk.
Association of Type 1 Diabetes With Standardized Test Scores of Danish Schoolchildren
Authors: Niels Skipper, Amanda Gaulke, Stine Møller Sildorf, Tine M. Eriksen, Nick Fabrin Nielsen, Jannet Svensson
Journal: JAMA (2019)

<h3>Importance</h3> Type 1 diabetes has been associated with cardiovascular disease and late complications such as retinopathy and nephropathy. However, it is unclear whether there is an association between type 1 diabetes and school performance in children. <h3>Objective</h3> To compare standardized reading and mathematics test scores of schoolchildren with type 1 diabetes vs those without diabetes. <h3>Design, Setting, and Participants</h3> Population-based retrospective cohort study from January 1, 2011, to December 31, 2015 (end date of follow-up), including Danish public schoolchildren attending grades 2, 3, 4, 6, and 8. Test scores were obtained in math (n = 524 764) and reading (n = 1 037 006). Linear regression models compared outcomes with and without adjustment for socioeconomic characteristics. <h3>Exposures</h3> Type 1 diabetes. <h3>Main Outcomes and Measures</h3> Primary outcomes were pooled test scores in math and reading (range, 1-100). <h3>Results</h3> Among 631 620 included public schoolchildren, the mean (SD) age was 10.31 (SD, 2.42) years, and 51% were male; 2031 had a confirmed diagnosis of type 1 diabetes. Overall, the mean combined score in math and reading was 56.11 (SD, 24.93). There were no significant differences in test scores found between children with type 1 diabetes (mean, 56.56) and children without diabetes (mean, 56.11; difference, 0.45 [95% CI, −0.31 to 1.22]). The estimated difference in test scores between children with and without type 1 diabetes from a linear regression model with adjustment for grade, test topic, and year was 0.24 (95% CI, −0.90 to 1.39) and 0.45 (95% CI, −0.58 to 1.49) with additional adjustment for socioeconomic status. <h3>Conclusions and Relevance</h3> Among Danish public schoolchildren, there was no significant difference in standardized reading and mathematics test scores of children with type 1 diabetes compared with test scores of children without diabetes.
EoE, OIT and Anaphylaxis: an unsolved puzzle.
Authors: Catherine Sonaly Ferreira Martins, Pablo Torres, Andressa Zanandrea, Antonio Penido, Claudia Castilho Mouco, Letícia Pereira da Silva, Claudia Leiko Yonekura Anagusko, Mariele Morandin Lopes, Joao Paulo de Assis, Juliana Mendonca, Patricia Salles-Cunha, Keity Souza Santos, Fabio M. Castro, Ariana C. Yang
Journal: Journal of Allergy and Clinical Immunology (2019)
The effect of surgical versus transcatheter aortic valve replacement on endothelial function. An observational study
Authors: Marco Moscarelli, Fiorella Devito, Khalil Fattouch, Patrizio Lancellotti, Marco Matteo Ciccone, Paola Rizzo, Mario Gaudino, Alfredo Marchese, Gianni Angelini, Giuseppe Speziale
Journal: International Journal of Surgery (2019)
Re: Fojecki G, Tiessen S, Osther PJ. Effect of Linear, Low-intensity Extracorporeal Shock Wave Therapy for Erectile Dysfunction. Eur Urol Suppl 2018;17:e1701
Authors: Tatjana Sramkova, Igor Motil, Jiri Jarkovsky, Katerina Sramkova
Journal: European Urology (2019)
Reviewer Acknowledgment 2012
Authors: Otis W. Brawley, Ted Gansler
Journal: CA A Cancer Journal for Clinicians (2012)

The editors of CA depend on the wisdom and advice of many experts in deciding which topics to pursue, which manuscripts to publish, and what modifications to make to ensure medical and scientific accuracy and suitability for our readers. We thank our Associate Editors, who have performed these services for us in the past year. We are also greatly indebted to the expertise, dedication, and expeditious response of the following individuals for reviewing at least one and, in some cases, many manuscripts for the journal from July 1, 2011, to June 30, 2012. Ghassan Abou-Alfa Robert Arceci Gerhardt Attard Paige Clark William Dahut Robert Debernardo Craig Earle Jens Eickhoff Michael Ewer Julio Garcia-Aguilar Stephen Golding Noah Hahn Minia Hellan Donald Henson Sarah Hoffe Linda Jacobs Paul Jacobsen Vinod Joshi Rajesh Lalla David Mankoff Hemant Roy Jorge Saavedra David Shibata Yun Yen
Infographic. Nutrition and oral health in sport: time for action
Authors: Ian Needleman, Alan Rankin, Paul Ashley, Tom Fairbrother, Peter Fine, Julie Gallagher, Dan Kings, Ronald John Maughan, Anna Katarina Melin, Michael Naylor
Journal: British Journal of Sports Medicine (2019)

Our recent BJSM editorial stressed that it is ‘time for action’ regarding sports nutrition oral health.1 Oral health is poor in elite athletes and is consistently associated with performance impacts as we have shown across studies involving more than 800 athletes.2–4 This situation exists despite poor oral health being preventable with well-evidenced effective, low-cost strategies.5 Since solutions are readily available why does this situation persist …
Perinatal Depression
Authors: Marlene P. Freeman
Journal: JAMA (2019)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Black Patients Experience Highest Rates of Specific Cancer-Associated Venous Thromboembolism: A Study Based at a Large Safety-Net Hospital in New England
Authors: Nana Oduraa Addo-Tabiri, Rani Chudasama, Rhythm Vasudeva, Orly Leiva, Brenda Garcia, Jonathan Ravid, Bunze Tamala, Linda Rosen, Mostafa Belghasem, Janice Weinberg, Ryan Ferguson, Brett Johnson, Mary Brophy, Vipul Chitalia
Journal: Blood (2018)
Cellular and molecular consequences of Patched haploinsufficiency: Perturbation of cell cycle and signal transduction pathways in the developing cerebellum
Authors: Jennifer M. Leonard, Karen Baskerville, Ye Hong, Michael McKinney, Cynthia Wetmore
Journal: Cancer Research (2005)

4611  Sonic hedgehog (Shh) signaling regulates proliferation and cell fate determination in the developing nervous system. Mutations of a component of the Shh receptor complex, Patched (Ptch), are associated with developmental anomalies and the formation of medulloblastoma. These tumors are thought to arise from the external germinal cell layer (EGL) of the developing cerebellum as they express Math-1, a marker of cells in the EGL. To identify intracellular as well as extracellular signals that predispose cells of the developing cerebellum to undergo neoplastic transformation, we sought to identify genes whose expression was modulated by Ptch haploinsufficiency in the EGL and IGL of developing murine cerebellum. So as to avoid perturbing gene expression by in vitro passage or purification of the cells and to capture the entire EGL microenvironment, discrete regions of postnatal day 6 murine cerebellum were isolated using laser assisted microdissection. Gene expression profiles from the external germinal (EGL) and internal germinal (IGL) layer were generated using Affymetrix mouse 2.0 gene arrays. A distinct cohort of > 100 genes differentially expressed between Ptch +/− EGL and WT EGL (p
The Novel Tumor Suppressor SAMHD1 Is Differentially Expressed and Partly Regulated By MYC in Peripheral T-Cell Lymphomas (PTCL)
Authors: Pedro Farrajota Neves Da Silva, Nikolaos Tsesmetzis, Ioanna Xagoraris, Agata Magdalena Wasik, Georgia Kokaraki, Evangelos Tzoras, Anders Österborg, Birgitta Sander, Nikolas Herold, George Rassidakis
Journal: Blood (2018)
Survival and cost associated with chemotherapy and chemoradiotherapy among resected pancreas cancer patients.
Authors: Nivethan Vela, Laura Davis, Stephanie Y Cheng, Ahmed Hammad, Ying Liu, Daniel Kagedan, Lev Bubis, Craig Earle, Lawrence Frank Paszat, Sten Myrehaug, Alyson L. Mahar, Nicole Mittmann, Natalie G. Coburn
Journal: Journal of Clinical Oncology (2019)

351 Background: Pancreas cancer is expensive to treat, and the effectiveness of adjuvant chemotherapy (CT) and chemoradiation (CRT) following resection is debated. We compared both survival and healthcare costs by adjuvant therapy after curative-intent pancreaticoduodenectomy (PD) for pancreas adenocarcinoma (PC). Methods: All patients with resected PC in Ontario, Canada diagnosed 2004 to 2014 were identified and linked to administrative healthcare databases. Stratified Kaplan—Meier survival curves and log-rank test compared survival across treatment groups. Costs were assessed from the perspective of Ontario’s single-payer healthcare system and compared between CT and CRT. A one-year time horizon was used from the date of surgery. Results: 677 PC patients met all inclusion/exclusion criteria and underwent curative-intent PD with 77% receiving CT and 23% CRT. Median survival after resection was 21.7 and 18.9 months for CT and CRT groups, respectively. Patients receiving CRT were less likely to have high comorbidity burden (ADG ≥ 10), but were similar across other demographics. CRT patients were more likely to have margin positive disease. In a subgroup of 489 patients with margin negative disease, median survival in the node negative patients (n = 156) was 28.0 months for CRT and 24.7 months for CT (p = 0.8297, logrank). Median survival in the node positive patients (n = 333) was 20.6 months and 21.8 months for the CRT and CT patients, respectively (p = 0.9856, logrank). The median total one-year cost for CT was $52,575 (USD); CRT was $68,216 (Table 1). Conclusions: Patients who underwent adjuvant CT and CRT after PD for PC had similar overall survival, but healthcare expenditures were significantly higher in the CRT group. [Table: see text]
Increasing Hypersensitivity Pneumonitis–related Mortality in the United States from 1988 to 2016
Authors: Evans R. Fernández Pérez, David B. Sprunger, Pailin Ratanawatkul, Lisa A. Maier, Tristan J. Huie, Jeffrey J. Swigris, Joshua J. Solomon, Michael P. Mohning, Rebecca C. Keith, Kevin K. Brown
Journal: American Journal of Respiratory and Critical Care Medicine (2019)
Application of Guideline-Based Definition of Severe Asthma Exacerbation with Objective and Subjective Methods to Evaluate Sensitivity on Treatment Response in a Randomized Controlled Trial
Authors: Cindy L.J. Weinstein, Nicholas Ryan, Davis Gates, Xiaoli Zhang, Tulin Shekar, Stephen J. Lane, Ioana O. Agache, Robert A. Nathan
Journal: Journal of Allergy and Clinical Immunology (2019)
Abstract 19679: Interrogation of Non-culprit Stenoses in Patients With St-segment Elevation Myocardial Infarction: A Comparison Between Ffr and Ifr
Authors: Nina W van der Hoeven, Gladys N Janssens, Guus A de Waard, Henk Everaars, Casper Wh Beijnink, Peter M van de Ven, Robin Nijveldt, Roberto Diletti, Christopher M Cook, Justin E Davies, Maarten A.H. van Leeuwen, Niels van Royen
Journal: Circulation (2017)

Introduction: Primary percutaneous intervention (PPCI) of non-culprit vessels in ST-segment elevation myocardial infarction (STEMI) patients is associated with improved clinical outcome. Fractional flow reserve (FFR) can guide revascularization of these non-culprit lesions. Recently instantaneous wave free ratio (iFR) was introduced as an adenosine-free alternative to FFR in patients with stable coronary artery disease and non-STEMI. In the acute setting of STEMI, coronary hemodynamics are altered, potentially influencing both FFR and iFR. Hypothesis: We hypothesize that FFR increases and iFR decreases from the index procedure to follow-up in patients with STEMI. Methods: We included 43 STEMI patients with an additional non-culprit coronary lesion. Following successful PPCI, resting and hyperaemic intracoronary pressure measurements were performed. These measurements were repeated at 1-month follow-up. FFR and iFR were calculated for both time-points. Results: FFR significantly decreased (0.89±0.07 versus...