tbuckley/cabot-search huggingface dataset:
COMPARISON OF LONG-TERM SUCCESS RATES OF EUS GUIDED BILIARY DRAINAGE VIA EUS GUIDED TRANSMURAL AND TRANSPAPILLARY APPROACH - A SINGLE CENTER RETROSPECTIVE COMPARATIVE STUDY
Authors: S Dharamsi, P Dashatwar, G Lakamaji, R Pujari, H Gadhikar, A Bapaye
Journal: Endoscopy (2020)

Aims EUS guided biliary drainage (EUS-BD) is an accepted treatment after failed ERCP in patients with malignant biliary obstruction (MBO). Transpapillary (TP) [antegrade, rendezvous] or Transmural (TM) [choledochoduodenostomy, hepatogastrostomy] approach may be used. This study compares long-term success rates of EUS-BD by TM or TP.
Impact of the Coronavirus (COVID-19) pandemic on surgical practice - Part 2 (surgical prioritisation)
Authors: Ahmed Al-Jabir, Ahmed Kerwan, Maria Nicola, Zaid Alsafi, Mehdi Khan, Catrin Sohrabi, Niamh O'Neill, Christos Iosifidis, Michelle Griffin, Ginimol Mathew, Riaz Agha
Journal: International Journal of Surgery (2020)
PERCUTANEOUS SEMS INSERTION AS A SALVAGE TECHNIQUE IN CASES OF UNSUCCESSFUL RETROGRADE CANNULATION IN MALIGNANT HILAR BILIARY STRICTURES
Authors: I Popadiin, K Katzarov, Z Dunkov, A Katzarov
Journal: Endoscopy (2020)

Aims The purpose of the study was to evaluate the technical and clinical efficacy, hospital stay and survival of antegrade stent placement following failed endoscopic cannulation of hilar strictures
THE OOPS STUDY: THE OOSTENDE POLYP SIZING STUDY
Authors: SV Langendonck, A Billiet, K Hertveldt, M Cool, G Lambrecht, G Deboever
Journal: Endoscopy (2020)

Aims Polyp size is one of the defining characteristics after polypectomy to decide the surveillance recommendations. In current practice, this is often based on endoscopic estimation.
DUODENAL CHOLECYST FISTULA: UNUSUAL PRESENTATION OF GALLBLADDER CANCER
Authors: R Palos-Cuéllar, OVH Mondragon, EM Perez, GB Velasco, RA Zamarripa Mottu, OMS Pineda, AM Bautista, PMS Hernandez
Journal: Endoscopy (2020)

80 year-old female was sent to our service for obstructive jaundice. Began 6 months ago with: abdominal pain, jaundice, dark urine, weight loss of 8 kg. Total bilirubin 7 umol/L. Abdominal ultrasound: common bile duct 12 mm.
Ventricular assist devices.
Authors: B Glenville, D Ross
Journal: BMJ (1986)

BRmuMEWCALJOURNAL VoLUME 292 8 8 m 1986 361 infants in hospital might receieunney, traverpous antibiotics if thought to have pneo toes early.diagnmisl mae any diference to thc r - idiial medical practitioners variously r d erythromytin or co-e sbutamol, stioids, tit sve, ves, and atropine methonitrate.Reviewing published re orts on treatment, Btoomhall adl hFhere was no firi evidetice for-the value oft4'ese.Maniy s bee thateary diagnos isworth-while on the nds thatteent withantibiotics, which needs to be forat least 14 days, reduces infectivity and-therefore limits spread.Tis may be useful when patients are admitted to a hospital ward, but at home old fashioned quarantine is likely to be as effective.Unfortunately, treating asymptomatic close contacts has not been proved protective.8Perhaps the most important reason for trying to make a correct diagnosis in the child at home is the reliefofp iOtalranxlety inevitable when there is uncertainty.The onlyway to peent i exitreel unpleasant disease is to encourake a high uptake of vaccine.
Infection of bat and human intestinal organoids by SARS-CoV-2
Authors: Jie Zhou, Cun Li, Xiaojuan Liu, Man Chun Chiu, Xiaoyu Zhao, Dong Wang, Yuxuan Wei, Andrew Lee, Anna Jinxia Zhang, Hin Chu, Jian-Piao Cai, Cyril Chik-Yan Yip, Ivy Hau-Yee Chan, Kenneth Kak-Yuen Wong, Owen Tak-Yin Tsang, Kwok-Hung Chan, Jasper Fuk-Woo Chan, Kelvin Kai-Wang To, Honglin Chen, Kwok Yung Yuen
Journal: Nature Medicine (2020)

A novel coronavirus—severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)—emerged in humans in Wuhan, China, in December 2019 and has since disseminated globally1,2. As of April 16, 2020, the confirmed case count of coronavirus disease 2019 (COVID-19) had surpassed 2 million. Based on full-genome sequence analysis, SARS-CoV-2 shows high homology to SARS-related coronaviruses identified in horseshoe bats1,2. Here we show the establishment and characterization of expandable intestinal organoids derived from horseshoe bats of the Rhinolophus sinicus species that can recapitulate bat intestinal epithelium. These bat enteroids are fully susceptible to SARS-CoV-2 infection and sustain robust viral replication. Development of gastrointestinal symptoms in some patients with COVID-19 and detection of viral RNA in fecal specimens suggest that SARS-CoV-2 might cause enteric, in addition to respiratory, infection3,4. Here we demonstrate active replication of SARS-CoV-2 in human intestinal organoids and isolation of infectious virus from the stool specimen of a patient with diarrheal COVID-19. Collectively, we established the first expandable organoid culture system of bat intestinal epithelium and present evidence that SARS-CoV-2 can infect bat intestinal cells. The robust SARS-CoV-2 replication in human intestinal organoids suggests that the human intestinal tract might be a transmission route of SARS-CoV-2. Bat and human intestinal organoids can support replication of SARS-CoV-2, enabling further characterization of the virus lifecycle and investigation of potential mechanisms of enteric infection in COVID-19.
RECOGNIZING POST-ENDOSCOPY COMPLICATIONS IN IN-PATIENTS: A DATABASE FILTER REDUCES QUALITY ASSURANCE WORKLOAD
Authors: P Karatzas, T Rösch, I Papanikolaou, J de Heer, G Schachschal, S Groth
Journal: Endoscopy (2020)

Aims Documentation of complications of GI endoscopy within the commonly used endoscopy documentation systems are mostly limited to acute complications during endoscopy included in the post-procedural endoscopy report. Later complications which are often even more relevant require individual patient follow-up creating substantial workload if taken seriously. We tested a documentation system based filter to reduce this workload by maintaining a high sensitivity to recognize post-endoscopy complications in an in-patient hospital system for interventional endoscopy
ENDOSCOPIC FULL THICKNESS RESECTION (EFTR) VERSUS ENDOSCOPIC SUBMUCOSAL DISSECTION (ESD) OF RESIDUAL/RECURRENT COLONIC LESIONS ON SCAR: A RETROSPECTIVE ITALIAN AND JAPANESE COMPARATIVE STUDY
Authors: F Barbaro, K Hirasawa, G Gibiino, R Kobayashi, J Hamanaka, S Pecere, Ta Fukuchi, L Petruzziello, G Costamagna
Journal: Endoscopy (2020)

Aims ESD for residual/recurrent colonic lesions on scar is technically difficult with a significant rate of perforations even in Japanese expert hands. Endoscopic full thickness resection (EFTR) with a over-the-scope device (FTRD - Ovesco Endoscopy), recently introduced in Western countries, showed to be safe and effective for residual/recurrent colonic lesions on scar . This study sought to compare outcomes for endoscopic resection of such lesions between a Japanese and an Italian tertially referral centre.
A Fresh New Look, and a Fresh New Journal
Authors: Richard J. Bucala, Marian T. Hannan
Journal: Arthritis & Rheumatology (2018)

Arthritis & RheumatologyVolume 71, Issue 1 p. 1-1 Editorial A Fresh New Look, and a Fresh New Journal Richard J. Bucala MD, PhD, Corresponding Author Editor-in-Chief, Arthritis & Rheumatology richard.bucala@yale.edu orcid.org/0000-0001-5783-5736 Yale University School of Medicine, New Haven, ConnecticutAddress correspondence to Richard J. Bucala, MD, PhD, Section of Rheumatology, Yale University School of Medicine, New Haven, CT. E-mail: richard.bucala@yale.edu.Search for more papers by this authorMarian T. Hannan DSc, MPH, Editor-in-Chief, Arthritis Care & Research orcid.org/0000-0002-9586-6928 Hebrew SeniorLife, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MassachusettsSearch for more papers by this author Richard J. Bucala MD, PhD, Corresponding Author Editor-in-Chief, Arthritis & Rheumatology richard.bucala@yale.edu orcid.org/0000-0001-5783-5736 Yale University School of Medicine, New Haven, ConnecticutAddress correspondence to Richard J. Bucala, MD, PhD, Section of Rheumatology, Yale University School of Medicine, New Haven, CT. E-mail: richard.bucala@yale.edu.Search for more papers by this authorMarian T. Hannan DSc, MPH, Editor-in-Chief, Arthritis Care & Research orcid.org/0000-0002-9586-6928 Hebrew SeniorLife, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MassachusettsSearch for more papers by this author First published: 27 December 2018 https://doi.org/10.1002/art.40717Citations: 1 This editorial is published simultaneously in Arthritis Care & Research. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinked InRedditWechat No abstract is available for this article.Citing Literature Volume71, Issue1January 2019Pages 1-1 RelatedInformation
Issues of Cardiovascular Risk Management in People With Diabetes in the COVID-19 Era
Authors: Antonio Ceriello, Eberhard Standl, Doina Catrinoiu, Baruch Itzhak, Nebojsa M. Lalic, Dario Rahelic, Oliver Schnell, Jan Škrha, Paul Valensi
Journal: Diabetes Care (2020)

People with diabetes compared with people without exhibit worse prognosis if affected by coronavirus disease 2019 (COVID-19) induced by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), particularly when compromising metabolic control and concomitant cardiovascular disorders are present. This Perspective seeks to explore newly occurring cardio-renal-pulmonary organ damage induced or aggravated by the disease process of COVID-19 and its implications for the cardiovascular risk management of people with diabetes, especially taking into account potential interactions with mechanisms of cellular intrusion of SARS-CoV-2. Severe infection with SARS-CoV-2 can precipitate myocardial infarction, myocarditis, heart failure, and arrhythmias as well as an acute respiratory distress syndrome and renal failure. They may evolve along with multiorgan failure directly due to SARS-CoV-2–infected endothelial cells and resulting endotheliitis. This complex pathology may bear challenges for the use of most diabetes medications in terms of emerging contraindications that need close monitoring of all people with diabetes diagnosed with SARS-CoV-2 infection. Whenever possible, continuous glucose monitoring should be implemented to ensure stable metabolic compensation. Patients in the intensive care unit requiring therapy for glycemic control should be handled solely by intravenous insulin using exact dosing with a perfusion device. Although not only ACE inhibitors and angiotensin 2 receptor blockers but also SGLT2 inhibitors, GLP-1 receptor agonists, pioglitazone, and probably insulin seem to increase the number of ACE2 receptors on the cells utilized by SARS-CoV-2 for penetration, no evidence presently exists that shows this might be harmful in terms of acquiring or worsening COVID-19. In conclusion, COVID-19 and related cardio-renal-pulmonary damage can profoundly affect cardiovascular risk management of people with diabetes.
A Vexed Question
Journal: JAMA (1969)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
EVALUATION OF ADVANCED ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY (ERCP) TECHNIQUES FOR SELECTIVE BILIARY CANNULATION
Authors: IG de la Filia Molina, JRF Olcina, DR Lázaro, ER de Santiago, RS Aldehuelo, SL Durán, AGG de Paredes, JÁG Martín, EV Sequeiros, AA Martínez
Journal: Endoscopy (2020)

Aims Selective biliary cannulation (SBC) by standard methods (SM) in endoscopic retrograde cholangiopancreatography (ERCP) can be unsuccessful in up to 20% of patients. When SM of SBC fail, a variety of advanced cannulation techniques (ACT) are available. The aim of the study was to evaluate the effectiveness, security and predisposing factors of ACT
SAFETY OF THE SELF-EXPANDABLE METAL STENTS FOR METASTATIC COLORECTAL CANCER PATIENTS WITH BEVACIZUMAB THERAPY
Authors: CW Min, HW Kim, BM Ko, HJ Goong, MS Lee
Journal: Endoscopy (2020)

Aims Self-expanding metal stents (SEMS) can be considered as initial treatment for malignant colorectal obstruction (MCO) in the palliative setting. Avastin (Bevacizumab), a monoclonal antibody targeting the vascular endothelial growth factor (VEGF) receptor is the first anti-angiogenesis drug used in colorectal cancer. However, data on the safety of bevacizumab- based therapies for patients carrying a SEMS for occlusive colon cancer are lacking. We aimed to evaluate the safety and clinical outcomes of the SEMS for MCO during bevacizumab- based chemotherapy.
DETECTION OF HIATAL HERNIAS: COMPARISON OF UPPER ENDOSCOPY AND HIGH-RESOLUTION MANOMETRY
Authors: V Kaibysheva, S Shapovaliantc, E Fedorov
Journal: Endoscopy (2020)

Aims The diagnosis of a hiatal hernia (HH) can be made by contrast enhanced X-ray examination and upper endoscopy. Data regarding the ability of high-resolution manometry (HRM) to identify HH remains limited. The aim of this study was to compare the diagnostic value of upper endoscopy and HRM in HH detection.
SELF-COMPLETION ENDOSCOPIC SUBMUCOSAL DISSECTION USING ENDOSABER FOR SUPERFICIAL ESOPHAGEAL NEOPLASMS
Authors: M Esaki, R Ichijima, S Suzuki, C Kusano, H Ikehara, T Gotoda
Journal: Endoscopy (2020)

Aims Endoscopic submucosal dissection (ESD) is an effective local treatment for gastrointestinal tract tumors. We invented self-completion ESD (SESD) using a novel needle-type knife, the Endosaber, which can cut, coagulate, and inject. SESD eliminates the need for assistance or use of additional devices, such as injection needles and hemostatic forceps. This was the first study to evaluate the effectiveness of SESD in patients with superficial esophageal neoplasms.
Monitoring and Handing of 89Sr Injection Site Extravasation in a Patient With Breast Cancer
Authors: Jiali Tang, Xiaolin Fu, Yishu Hu, Yiyuan Zhang, Fuqiang Shao
Journal: Clinical Nuclear Medicine (2020)

Abstract Extravasation of various imaging tracers during administration was not a rare complication during nuclear medicine practice. However, the occurrence of extravasation of therapeutic radiopharmaceutical was rarely reported. Here we reported a 60-year-old woman with breast cancer and diffuse painful bone metastases who received strontium chloride ( 89 SrCl 2 ) therapy to palliate her bone pain. Accidental subcutaneous extravasation in the injection site occurred. The extravasated 89 Sr was absorbed rapidly by arm elevation, squeezing a stress ball, local warming, and gently massaging. Follow-up results showed the patient's bone pain significantly relieved and her right arm remained normal.
USEFULNESS OF SODIUM ALGINATE FOR INJECTION SOLUTION IN COLORECTAL ENDOSCOPIC SUBMUCOSAL DISSECTION
Authors: K Yamamoto, Y Takagi, T Nakamura, Y Tokuda, T Kanno, S Hiyama, N Tatsumi, T Ito
Journal: Endoscopy (2020)

Aims Colorectal endoscopic submucosal dissection (ESD) is technically difficult especially when the submucosal layer cannot be sufficiently lifted even after submucosal injection. Therefore, the choice of injection solution is very important, and hyaluronic acid has been considered as the best injection solution for colorectal ESD. However, hyaluronic acid is expensive, and some lesions cannot be sufficiently lifted or kept lifted for a long time even after its use. On the other hand, sodium alginate (Liftal K, Kaigen Pharma Co., Osaka) is a novel injection solution extracted from seaweeds, and has high viscosity. Sodium alginate is also used as medicines for protection of gastric mucosa or hemostasis, and costs lower than hyaluronic acid. It has recently been reported it is useful for gastric ESD and esophageal ESD, but its usefulness for colorectal ESD is not elucidated. We therefore investigated the efficacy of sodium alginate for colorectal ESD.
Designs of colonoscopic adenoma detection trials: more positive results with tandem than with parallel studies - an analysis of studies on imaging techniques and mechanical devices
Authors: Katharina Zimmermann-Fraedrich, Heiko Pohl, Thomas Rösch, Douglas K Rex, Cesare Hassan, Evelien Dekker, Michal Filip Kaminski, Michael Bretthauer, Jocelyn de Heer, Yuki Werner, Guido Schachschal, Stefan Groth
Journal: Gut (2020)

Background and aims Adenoma detection rate (ADR) has been shown to correlate with interval cancers after screening colonoscopy and is commonly used as surrogate parameter for its outcome quality. ADR improvements by various techniques have been studied in randomised trials using either parallel or tandem methodololgy. Methods A systematic literature search was done on randomised trials (full papers, English language) on tandem or parallel studies using either adenoma miss rates (AMR) or ADR as main outcome to test different novel technologies on imaging (new endoscope generation, narrow band imaging, iScan, Fujinon intelligent chromoendoscopy/blue laser imaging and wide angle scopes) and mechanical devices (transparent caps, endocuff, endorings and balloons). Available meta analyses were also screened for randomised studies. Results Overall, 24 randomised tandem trials with AMR (variable definitions and methodology) and 42 parallel studies using ADR (homogeneous methodology) as primary outcome were included. Significant differences in favour of the new method were found in 66.7% of tandem studies (8222 patients) but in only 23.8% of parallel studies (28 059 patients), with higher rates of positive studies for mechanical devices than for imaging methods. In a random-effects model, small absolute risk differences were found, but these were double in magnitude for tandem as compared with parallel studies (imaging: tandem 0.04 (0.01, 0.07), parallel 0.02 (0.00, 0.04); mechanical devices: tandem 0.08 (0.00, 0.15), parallel 0.04 (0.01, 0.07)). Nevertheless, 94.2% of missed adenomas in the tandem studies were small (&lt;1 cm) and/or non-advanced. Conclusions A tandem study is more likely to yield positive results than a simple parallel trial; this may be due to the use of different parameters, variable definitions and methodology, and perhaps also a higher likelihood of bias. Therefore, we suggest to accept positive results of tandem studies only if accompanied by positive results from parallel trials.
MODIFIED PER ORAL ENDOSCOPIC MYOTOMY FOR ZENKER´S DIVERTICULUM (Z-POEM) WITH MUCOSAL INCISION OVER THE SEPTUM
Authors: G Mavrogenis, I Tsevgas, D Zachariadis
Journal: Endoscopy (2020)

Methods A mucosal incision is created along the edge of the septum using a therapeutic gastroscope. Then a tunnel is performed on both sides of the septum and complete myotomy is performed. Finally, large clips are applied at the mucosal entry.
BSG EQIP UPPER GI HAEMOSTASIS COURSE QUALITY IMPROVEMENT PROJECT
Authors: V Mehta, M Rajawat, M Thoufeeq
Journal: Endoscopy (2020)

Aims The aim of this project was to assess the knowledge and skills of medical and paramedical staff in managing the Upper Gastro-intestinal bleeding (UGIB), pre- and post-UGIB haemostasis course and the benefits of conducting it.
Could the smoking gun in the fight against COVID-19 be the (rh)ACE-2?
Authors: Dhamend Lutchman
Journal: European Respiratory Journal (2020)

<b>Exogenous supplement of recombinant human (rh)ACE-2 might be a brilliant idea in the treatment of COVID-19. Soluble ACE-2 might impact viral spread, since binding to soluble receptor has been shown to block SARS-CoV-2 entry.</b>https://bit.ly/3bsUKO2
Thyroidectomy Versus Medical Management for Euthyroid Patients With Hashimoto Disease and Persisting Symptoms
Authors: Ivar Guldvog, Laurens Cornelus Reitsma, Lene Johnsen, Andromeda Lauzike, Charlotte Gibbs, Eivind Carlsen, Tone Hoel Lende, Jon Kristian Narvestad, Roald Omdal, Jan Terje Kvaløy, Geir Hoff, Tomm Bernklev, Håvard Søiland
Journal: Annals of Internal Medicine (2019)

Despite adequate hormone replacement, some patients with Hashimoto disease have residual symptoms that may be related to immune pathophysiology rather than to hypothyroidism. This randomized trial ...
Adjuvant nivolumab plus ipilimumab or nivolumab monotherapy versus placebo in patients with resected stage IV melanoma with no evidence of disease (IMMUNED): a randomised, double-blind, placebo-controlled, phase 2 trial
Authors: Lisa Zimmer, Elisabeth Livingstone, Jessica C Hassel, Michael Fluck, Thomas Eigentler, Carmen Loquai, Sebastian Haferkamp, Ralf Gutzmer, Friedegund Meier, Peter Mohr, Axel Hauschild, Bastian Schilling, Christian Menzer, Felix Kieker, Edgar Dippel, Alexander Rösch, Jan-Christoph Simon, Beate Conrad, Silvia Körner, Christine Windemuth-Kieselbach, Leonora Schwarz, Claus Garbe, Jürgen C Becker, Dirk Schadendorf, Carola Berking, Rudolf A Herbst, Uwe M Martens, Sabine Sell, Rudolf Stadler, Patrick Terheyden, Jochen Utikal
Journal: The Lancet (2020)
Hepatitis C Virus Reinfection after Successful Treatment with Direct-Acting Antiviral Therapy in a Large Population-Based Cohort
Authors: C Rossi, Z A Butt, S Wong, J Buxton, N Islam, A Yu, M Darvishian, M Gilbert, J Wong, N Chapinal, M Binka, M Alvarez, M Tyndall, M Krajden, N Janjua
Journal: Hepatology (2018)