tbuckley/cabot-search huggingface dataset:
A management algorithm for adult patients with both brain oxygen and intracranial pressure monitoring: the Seattle International Severe Traumatic Brain Injury Consensus Conference (SIBICC)
Authors: Randall Chesnut, Sergio Aguilera, Andras Buki, Eileen Bulger, Giuseppe Citerio, D. Jamie Cooper, Ramon Diaz Arrastia, Michael Diringer, Anthony Figaji, Guoyi Gao, Romer Geocadin, Jamshid Ghajar, Odette Harris, Alan Hoffer, Peter Hutchinson, Mathew Joseph, Ryan Kitagawa, Geoffrey Manley, Stephan Mayer, David K. Menon, Geert Meyfroidt, Daniel B. Michael, Mauro Oddo, David Okonkwo, Mayur Patel, Claudia Robertson, Jeffrey V. Rosenfeld, Andres M. Rubiano, Juan Sahuquillo, Franco Servadei, Lori Shutter, Deborah Stein, Nino Stocchetti, Fabio Silvio Taccone, Shelly Timmons, Eve Tsai, Jamie S. Ullman, Paul Vespa, Walter Videtta, David W. Wright, Christopher Zammit, Gregory W. J. Hawryluk
Journal: Intensive Care Medicine (2020)

Current guidelines for the treatment of adult severe traumatic brain injury (sTBI) consist of high-quality evidence reports, but they are no longer accompanied by management protocols, as these require expert opinion to bridge the gap between published evidence and patient care. We aimed to establish a modern sTBI protocol for adult patients with both intracranial pressure (ICP) and brain oxygen monitors in place. Our consensus working group consisted of 42 experienced and actively practicing sTBI opinion leaders from six continents. Having previously established a protocol for the treatment of patients with ICP monitoring alone, we addressed patients who have a brain oxygen monitor in addition to an ICP monitor. The management protocols were developed through a Delphi-method-based consensus approach and were finalized at an in-person meeting. We established three distinct treatment protocols, each with three tiers whereby higher tiers involve therapies with higher risk. One protocol addresses the management of ICP elevation when brain oxygenation is normal. A second addresses management of brain hypoxia with normal ICP. The third protocol addresses the situation when both intracranial hypertension and brain hypoxia are present. The panel considered issues pertaining to blood transfusion and ventilator management when designing the different algorithms. These protocols are intended to assist clinicians in the management of patients with both ICP and brain oxygen monitors but they do not reflect either a standard-of-care or a substitute for thoughtful individualized management. These protocols should be used in conjunction with recommendations for basic care, management of critical neuroworsening and weaning treatment recently published in conjunction with the Seattle International Brain Injury Consensus Conference.
Almost a third of UK doctors may be burnt out and stressed, study suggests
Authors: Abi Rimmer
Journal: BMJ (2020)

Doctors working in emergency medicine and general practice are most at risk of exhaustion, stress, and compassion fatigue, researchers have found.

The study, published in the online journal BMJ Open found that nearly one in three doctors (31.5%) had high levels of burnout, while one in four (26%) had high levels of stress.1

The results were based on 1651 responses to online surveys of UK …
Methionine Commits Cells to Differentiate Into Plasmablasts Through Epigenetic Regulation of <scp>BTB</scp> and <scp>CNC</scp> Homolog 2 by the Methyltransferase <scp>EZH</scp>2
Authors: Mingzeng Zhang, Shigeru Iwata, Maiko Hajime, Naoaki Ohkubo, Yasuyuki Todoroki, Hiroko Miyata, Masanobu Ueno, He Hao, Tong Zhang, Jie Fan, Shingo Nakayamada, Kaoru Yamagata, Yoshiya Tanaka
Journal: Arthritis & Rheumatology (2020)

Plasmablasts play important roles in autoimmune diseases, including systemic lupus erythematosus (SLE). Activation of mechanistic target of rapamycin complex 1 (mTORC1) is regulated by amino acid levels. In patients with SLE, mTORC1 is activated in B cells and modulates plasmablast differentiation. However, the detailed mechanisms of amino acid metabolism in plasmablast differentiation remain elusive. We undertook this study to evaluate the effects of methionine in human B cells.Purified CD19+ cells from healthy donors (n = 21) or patients with SLE (n = 35) were cultured with Toll-like receptor 7/9 ligand, interferon-α (IFNα), and B cell receptor crosslinking, and we determined the types of amino acids that were important for plasmablast differentiation and amino acid metabolism. We also identified the transcriptional regulatory mechanisms induced by amino acid metabolism, and we assessed B cell metabolism and its relevance to SLE.The essential amino acid methionine strongly committed cells to plasmablast differentiation. In the presence of methionine, Syk and mTORC1 activation synergistically induced methyltransferase EZH2 expression. EZH2 induced H3K27me3 at BTB and CNC homolog 2 (Bach2) loci and suppressed Bach2 expression, leading to induction of B lymphocyte-induced maturation protein 1 and X-box binding protein 1 expression and plasmablast differentiation. CD19+ cells from patients with SLE overexpressed EZH2, which was correlated with disease activity and autoantibody production.Our findings show that methionine activated signaling by controlling immunologic metabolism in B cells and played an important role in the differentiation of B cells into plasmablasts through epigenome modification of Bach2 by the methyltransferase EZH2.
Publisher Correction: PAK4 inhibition improves PD-1 blockade immunotherapy
Authors: Gabriel Abril-Rodriguez, Davis Y. Torrejon, Wei Liu, Jesse M. Zaretsky, Theodore S. Nowicki, Jennifer Tsoi, Cristina Puig-Saus, Ignacio Baselga-Carretero, Egmidio Medina, Michael J. Quist, Alejandro J. Garcia, William Senapedis, Erkan Baloglu, Anusha Kalbasi, Gardenia Cheung-Lau, Beata Berent-Maoz, Begoña Comin-Anduix, Siwen Hu-Lieskovan, Cun-Yu Wang, Catherine S. Grasso, Antoni Ribas
Journal: Nature Cancer (2020)
European Association of Urology Guidelines Office: How We Ensure Transparent Conflict of Interest Disclosure and Management
Authors: Emma Jane Smith, Karin Plass, Julie Darraugh, Robert Shepherd, Alberto Briganti, Philip Cornford, Thomas Knoll, Nicolaas Lumen, James N’Dow, Maria J. Ribal, Richard Sylvester, Hendrik van Poppel, Anders Bjartell
Journal: European Urology (2020)
Diffuse Hepatosplenic 99mTc-Pyrophosphate Activity Caused by Amyloidosis
Authors: Jingyun Ren, Chao Ren, Li Huo, Fang Li, Shuyang Zhang
Journal: Clinical Nuclear Medicine (2019)

Abstract A 46-year-old man underwent 99m Tc-pyrophosphate scan to evaluate possible infiltrative myocardiopathy revealed by echocardiography. The images did not show abnormal cardiac activity. However, diffuse abnormal activity in the liver and spleen was noted. Pathological examination from the specimen acquired from hepatic biopsy demonstrated amyloidosis, light chain type.
A curated benchmark of enhancer-gene interactions for evaluating enhancer-target gene prediction methods
Authors: Jill E. Moore, Henry E. Pratt, Michael J. Purcaro, Zhiping Weng
Journal: Genome biology (2020)

Many genome-wide collections of candidate cis-regulatory elements (cCREs) have been defined using genomic and epigenomic data, but it remains a major challenge to connect these elements to their target genes.
Respiratory medicine is not gender blind
Authors: Mina Gaga, Daiana Stolz, Joanna Chorostowska-Wynimko, Tobias Welte, Anita Simonds
Journal: European Respiratory Journal (2020)

Marie Curie is a legendary figure: her research had huge impact on medicine, and she was the first woman to receive a Nobel Prize. In fact, she received two, one in Physics in 1903, and one in Chemistry in 1911, and so early in the history of Nobel Prizes (they were first awarded in 1901) a woman was a laureate. This was before women's suffrage in most parts of the world, and before any notion of gender equality, when few women had a chance to follow a career in science or medicine or get any education, and Marie Curie showed that it was possible. She was admired, respected and a role model for women in science. But still, more than 100 years later, few women have followed her footsteps: Between 1901 and 2018, there have been 902 Nobel laureates and of those, 52 were women [1]. Few women are still promoted to leadership positions and there seems to be an unconscious bias that must be changed <http://bit.ly/2mET3t6>
Leveraging Gene Expression Subgroups to Classify DLBCL Patients and Enrich for Clinical Benefit to a Novel Agent
Authors: Alberto Risueno, Patrick Ryan Hagner, Fadi Towfic, Celia Fontanillo, Amira Djebbari, Joel S. Parker, Clifton Drew, Grzegorz S. Nowakowski, Matthew J. Maurer, James R. Cerhan, Xin Wei, Yan Ren, Chung-Wein Lee, Suzana Couto, Maria Wang, Michael Pourdehnad, Anita Krithivas Gandhi, Matthew William Burnell Trotter
Journal: Blood (2020)
Is it time to give up on “self-management” of COPD exacerbations?
Authors: Sanjay Ramakrishnan, Mona Bafadhel
Journal: European Respiratory Journal (2020)

<b>COPD exacerbation self-management does not reduce COPD exacerbation days or hospitalisation, rather to more oral corticosteroid use and is rarely effective as it is not targeted</b>http://bit.ly/33D89jF
Experiences of Individuals Who Were Physically Restrained in the Emergency Department
Authors: Ambrose H. Wong, Jessica M. Ray, Alana Rosenberg, Lauren Crispino, John Parker, Caitlin McVaney, Joanne D. Iennaco, Steven L. Bernstein, Anthony J. Pavlo
Journal: JAMA Network Open (2020)

<h3>Importance</h3> Individuals with behavioral disorders are increasingly presenting to the emergency department (ED), and associated episodes of agitation can cause significant safety threats to patients and the staff caring for them. Treatment includes the use of physical restraints, which may be associated with injuries and psychological trauma; to date, little is known regarding the perceptions of the use of physical restraint among individuals who experienced it in the ED. <h3>Objective</h3> To characterize how individuals experience episodes of physical restraint during their ED visits. <h3>Design, Setting, and Participants</h3> In this qualitative study, semistructured, 1-on-1, in-depth interviews were conducted with 25 adults (ie, aged 18 years or older) with a diverse range of chief concerns and socioeconomic backgrounds who had a physical restraint order associated with an ED visit. Eligible visits included those presenting to 2 EDs in an urban Northeast city between March 2016 and February 2018. Data analysis occurred between July 2017 and June 2018. <h3>Main Outcomes and Measures</h3> Basic participant demographic information, self-reported responses to the MacArthur Perceived Coercion Scale, and experiences of physical restraint in the ED. <h3>Results</h3> Data saturation was reached with 25 interviews (17 [68%] men; 18 [72%] white; 19 [76%] non-Hispanic). The time between the patient's last restraint and the interview ranged from less than 2 weeks to more than 6 months. Of those interviewed, 22 (88%) reported a combination of mental illness and/or substance use as contributing to their restraint experience. Most patients (20 [80%]) said that they felt coerced to present to the ED. Three primary themes were identified from interviews, as follows: (1) harmful experiences of restraint use and care provision, (2) diverse and complex personal contexts affecting visits to the ED, and (3) challenges in resolving their restraint experiences, leading to negative consequences on well-being. <h3>Conclusions and Relevance</h3> In this qualitative study, participants described a desire for compassion and therapeutic engagement, even after they experienced coercion and physical restraint during their visits that created lasting negative consequences. Future work may need to consider more patient-centered approaches that minimize harm.
Study of serine endopeptidase (H1 and H2), prolyl endopeptidase (PE) and neutral endopeptidase (NEP) purified from human urine and from fresh urine using fluorogenic substrate.
Authors: Beata Marie Redublo Quinto, Adriana Karaoglanovic Carmona, Maria Aparecida Juliano, Luiz Juliano, Nestor Schor, Dulce Elena Casarini
Journal: Journal of the American Society of Nephrology (1997)
High total metabolic tumor volume at baseline predicts survival independent of response to therapy
Authors: Laetitia Vercellino, Anne-Segolene Cottereau, Olivier Casasnovas, Hervé Tilly, Pierre Feugier, Loic Chartier, Christophe Fruchart, Louise Roulin, Lucie Oberic, Gian Matteo Pica, Vincent Ribrag, Julie Abraham, Marc Simon, Hugo Gonzalez, Reda Bouabdallah, Olivier Fitoussi, Catherine Sebban, Armando López-Guillermo, Laurence Sanhes, Franck Morschhauser, Judith Trotman, Bernadette Corront, Bachra Choufi, Sylvia Snauwaert, Pascal Godmer, Josette Briere, Gilles Salles, Philippe Gaulard, Michel Meignan, Catherine Thieblemont
Journal: Blood (2020)
Correction: Advanced imaging for detection and differentiation of colorectal neoplasia: European Society of Gastrointestinal Endoscopy (ESGE) Guideline – Update 2019
Authors: Raf Bisschops, James E. East, Cesare Hassan, Yark Hazewinkel, Michał F. Kamiński, Helmut Neumann, Maria Pellisé, Giulio Antonelli, Marco Bustamante Balen, Emmanuel Coron, Georges Cortas, Marietta Iacucci, Mori Yuichi, Gaius Longcroft-Wheaton, Serguei Mouzyka, Nastazja Pilonis, Ignasi Puig, Jeanin E. van Hooft, Evelien Dekker
Journal: Endoscopy (2019)

Correction to: Advanced imaging for detection and differentiation of colorectal neoplasia: European Society of Gastrointestinal Endoscopy (ESGE) Guideline – Update 2019Endoscopy 2019; 51(12): 1155-1179DOI: 10.1055/a-1031-7657
Annals Graphic Medicine - W.O.W.
Authors: Jennifer Ng
Journal: Annals of Internal Medicine (2020)

Web Exclusives21 January 2020Annals Graphic Medicine - W.O.W.FREEJennifer NgJennifer NgSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/G19-0017 SectionsAboutVisual AbstractPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Download figure Download PowerPoint Comments0 CommentsSign In to Submit A Comment Author, Article, and Disclosure InformationAffiliations: Disclosures: The author has disclosed no conflicts of interest. The form can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=G19-0017.Author/Illustrator Information: Jennifer Ng is a rheumatologist at Gold Coast University Hospital in Southport, Australia, and an adjunct associate professor at Griffith University (e-mail, jennih.[email protected]com). PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 21 January 2020Volume 172, Issue 2Page: W38KeywordsConflicts of interestDisclosureHealth care ePublished: 21 January 2020 Issue Published: 21 January 2020 Copyright & PermissionsCopyright © 2020 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Exposure to air pollution during childhood and risk of developing schizophrenia: a national cohort study
Authors: Sussie Antonsen, Pearl L H Mok, Roger T Webb, Preben B Mortensen, John J McGrath, Esben Agerbo, Jørgen Brandt, Camilla Geels, Jesper H Christensen, Carsten B Pedersen
Journal: The Lancet Planetary Health (2020)

BackgroundAmbient air pollution affects neurological function, but its association with schizophrenia risk is unclear. We investigated exposure to nitrogen oxides (NOX) as a whole and nitrogen dioxide (NO2) specifically, as well as PM10, and PM2·5, during childhood and subsequent schizophrenia risk.MethodsPeople born in Denmark from 1980 to 1984 (N=230 844), who were residing in the country on their tenth birthday, and who had two Danish-born parents were followed-up from their tenth birthday until schizophrenia diagnosis or Dec 31, 2016. Mean daily exposure to each pollutant (NO2, NOX, PM10, and PM2·5) at all of an individual's residential addresses from birth to their tenth birthday was modelled. Incidence rate ratios, cumulative incidence, and population attributable risks were calculated using survival analysis techniques.FindingsWe analysed data between Aug 1, 2018, and Nov 15, 2019. Of 230 844 individuals included, 2189 cohort members were diagnosed with schizophrenia during follow-up. Higher concentrations of residential NO2 and NOX exposure during childhood were associated with subsequent elevated schizophrenia risk. People exposed to daily mean concentrations of more than 26·5 μg/m3 NO2 had a 1·62 (95% CI 1·41–1·87) times increased risk compared with people exposed to a mean daily concentration of less than 14·5 μg/m3. The absolute risks of developing schizophrenia by the age of 37 years when exposed to daily mean concentrations of more than 26·5 μg/m3 NO2 between birth and 10 years were 1·45% (95% CI 1·30–1·62%) for men and 1·03% (0·90–1·17) for women, whereas when exposed to a mean daily concentration of less than 14·5 μg/m3, the risk was 0·80% (95% CI 0·69–0·92%) for men and 0·67% (0·57–0·79) for women. Associations between exposure to PM2·5 or PM10 and schizophrenia risk were less consistent.InterpretationIf the association between air pollution and schizophrenia is causal, reducing ambient air pollution including NO2 and NOX could have a potentially considerable effect on lowering schizophrenia incidence at the population level. Further investigations are necessary to establish a causal relationship.FundingLundbeck Foundation, Stanley Medical Research Institute, European Research Council, NordForsk, Novo Nordisk Foundation, National Health and Medical Research Council, Danish National Research Foundation.
Gene Set Enrichment Analysis of leukemic blasts from AML and ALL patients reveals biological pathways associated with sensitivity/resistance to plitidepsin treatment.
Authors: Gonzalo Gomez-Lopez, Nerea Martinez, Margarita Sanchez-Beato, Paloma De la Cueva, Miguel Aracil, Juan Carlos Tercero, Jose Jimeno, David Gonzalez-Pisano, Miguel Angel Piris
Journal: Cancer Research (2008)

1674  Aplidin® (plitidepsin) is a novel marine-derived anti-tumour agent in Phase II clinical trials, originally isolated from the tunicate Aplidium albicans and currently obtained by total synthesis. Aplidin® produces cell cycle G1 arrest, G2 blockage, and apoptosis through the activation of JNK and p38 MAPKs; in addition Aplidin® inhibits VEGF secretion. However, in spite of these findings, the mechanism of action of Aplidin® in tumour cells and those biological pathways involved in drug chemoresistance are only partially understood. In this study, blast cells explanted from 20 acute lymphoblastic (ALL) and 21 acute myeloid (AML) leukaemia patients with differential sensitivity to Aplidin® were analyzed. Blasts gene expression values were obtained using Oncochip, a cDNA microarray platform that contains 6700 genes relevant in cancer development and drug resistance. With the aim of finding significantly enriched Biocarta pathways (FDR
B16 The ROS1 Cancer Model Project: A Unique Patient-Driven Partnership to Accelerate Research
Authors: A.C. Moore, L. Goldman, T. Tomalia, R.C. Doebele, C.M. Lovly, R. Chiaverelli, T. Addario, A. Sable-Hunt, B. Addario, J. Freeman-Daily
Journal: Journal of Thoracic Oncology (2020)
Nanoparticle encapsulated core-shell hydrogel for on-site BMSCs delivery protects from iron overload and enhances functional recovery
Authors: Yuhua Gong, Yumei Wang, Qing Qu, Zongkun Hou, Tingwang Guo, Yingqian Xu, Rui Qing, Jia Deng, Bochu Wang, Shilei Hao
Journal: Journal of Controlled Release (2020)
Coordinated inhibition of nuclear export and Bcr-Abl1 selectively targets chronic myeloid leukemia stem cells
Authors: Hein Than, Anthony D. Pomicter, Dongqing Yan, Larry P. Beaver, Anna M. Eiring, William L. Heaton, Anna Senina, Phillip M. Clair, Sharon Shacham, Clinton C. Mason, Thomas O’ Hare, Michael W. Deininger
Journal: Leukemia (2020)
App Enables Sharing Off-label Treatments for Infectious Diseases
Authors: Rebecca Voelker
Journal: JAMA (2020)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
“When They Restrain You They Ignore You”—What We Should Learn From the People We Restrain in Emergency Departments
Authors: Abraham M. Nussbaum, Matthew K. Wynia
Journal: JAMA Network Open (2020)

Ambrose H. Wong, MD, MSEd; Jessica M. Ray, PhD; Alana Rosenberg, MPH; Lauren Crispino, BS; John Parker, BS; Caitlin McVaney, BS; Joanne D. Iennaco, PhD; Steven L. Bernstein, MD; Anthony J. Pavlo, PhD
Validation of the FIRST simplified frailty scale using the ECOG performance status instead of patient-reported activities
Authors: Claudia A. M. Stege, Bronno van der Holt, Avinash G. Dinmohamed, Pieter Sonneveld, Mark-David Levin, Niels W. C. J van de Donk, Ulf-Henrik Mellqvist, Anders Waage, Sonja Zweegman
Journal: Leukemia (2020)
Erlotinib as Neoadjuvant Treatment in Patients with IIIA-N2 Non-Small Cell Lung Cancer(NSCLC) With Activating Epidermal Growth Factor Receptor (EGFR) Mutation (NCT01217619, ESTERN)
Authors: B. Han, L. Xiong, R. Li, J. Sun, Y. Lou, Y. Zhang
Journal: Annals of Oncology (2012)
IA21 ASCL1 Represses a Latent Osteogenic Program in Small-Cell Lung Cancer Arising from Multiple Cells of Origin
Authors: R.R. Olsen, D.W. Kastner, A.S. Ireland, K. Pozo, C.P. Whitney, M.R. Guthrie, S.J. Wait, D. Soltero, B.L. Witt, A. Gazdar, J.E. Johnson, T.G. Oliver
Journal: Journal of Thoracic Oncology (2020)
Recurrent Immunoglobulin G4–Related Disease Shown on 18F-FDG and 68Ga-FAPI PET/CT
Authors: Qingqing Pan, Yaping Luo, Wen Zhang
Journal: Clinical Nuclear Medicine (2020)

A 21-year-old man had been diagnosed with immunoglobulin G4-related disease (IgG4-RD) for 5 years, and the disease recurred 1 month ago. F-FDG PET/CT revealed intense FDG activity in the pituitary stalk, submandibular gland, pleura, pericardium, pancreas, liver, prostate, and multiple lymph nodes, which were considered the involvements of IgG4-RD. Ga-FAPI PET/CT also showed intense Ga-FAPI uptake in the above FDG-avid lesions except the lymph node involvement. Additionally, involvement in the lacrimal glands was detected by Ga-FAPI. The positive findings of Ga-FAPI in the current case highlighted that Ga-FAPI may have value in the evaluation of IgG4-RD.
Abstract 10019: The Effects of Tobacco Smoking and Electronic Cigarette Use on the Level of Albuminuria and Vascular Augmentation Index in Young Healthy Population
Authors: Anna Bragina, Natalia Druzhinina, Leila Mohammadi, Evgenii Khvalin, Artem Dubchak, Luba Vasilyeva, Valery Podzolkov
Journal: Circulation (2019)

Aim: To study the level ofalbuminuriaand vascular augmentation index (Alx) in young population without diabetes and clinically significant cardiovascular diseases, who are tobacco smokers or using ...
Open-Label Phase II Trial of First-Line Everolimus Monotherapy in Patients with Advanced Papillary Renal Cell Carcinoma: Raptor Interim Analysis
Authors: B. Escudier, S. Bracarda, J.P. Maroto, C. Szczylik, P. Nathan, S. Negrier, K. Slimane, C. May, C. Porta, V. Grünwald
Journal: Annals of Oncology (2012)