AB0911 PREVALENCE AND RISK FACTORS OF HIP FRACTURE ASSOCIATED WITH OSTEOPOROSIS IN A GERIATRIC POPULATION FROM COLOMBIAN NORTH EAST.
Authors: M. Romero, M. Cadena, J. Osma, Y. Santamaria
Journal: Annals of the Rheumatic Diseases (2020)

Background: Hip fracture is a frequent cause of hospital admission in older adults. 1 The prevalence of hip fracture associated with osteoporosis in the elderly is 18% in women and 6% in men. 2 Likewise, the attention of this event requires an approximate value of 2,943 dollars, which represents an average of 18,95% of the per capita income of most countries. 3 It is also established that appropriate and timely treatment of osteoporosis can prevent the appearance of fractures. 4 Objectives: The aim of this study was to determine the prevalence of hip fracture associated with osteoporosis, as well as the associated factors to its presentation in a geriatric population in Colombia. Methods: Cross-sectional study that included 130 patients over 65 years old, who consulted the University Hospital of Santander with hip fracture. The main variable of exposition was the medical history of osteoporosis. Descriptive analysis was performed with absolute and relative frequency measurements for the qualitative variables and central tendency measures and dispersion according to the distribution of the variables. Subsequently, the bivariate logistic regression analysis was performed to identify the associated risk variables. The analysis was performed with the Stata 12.0 Software. Results: From the 130 patients included in the study, 33.85% corresponded to the male gender. The average age was 82.49 years with a DS of 8.35 years. The median length of hospital stay was 17.5 days with an interquartile range of 11 to 26 days. The most common comorbidity was hypertension in 65.38%, followed by diabetes and COPD in 21.54%, heart failure in 19.23% and chronic kidney disease in 17.69%. The median Charlson score was 5 with an interquartile range between 4 and 6 points. 13.85% of the patients admitted had concomitant osteoporosis, 77.7% of them were women and 8,46% of them had severe osteoporosis, with history of prior fracture, without treatment. In the bivariate analysis, an association was found between having COPD (OR: 4.89, 95% CI 1.71-13.95, p = 0.003), dementia (OR: 3.20, 95% CI 1.05-19.56, p = 0.044), malnutrition (OR: 3.42, IC95 % 1.10 - 10.60, p = 0.032), and osteoporosis associated with hip fracture at hospital admission. Likewise, a greater probability was found for the development of in-hospital pneumonia (OR: 2.48, 95% CI 1.14 - 7.98, p = 0.04) in patients with osteoporosis compared to those who did not have bone disease. Conclusion: 13.85% of patients who entered due to hip fracture had osteoporosis as comorbidity, data comparable to that previously reported. Variables associated with the presence of osteoporosis at admission in patients with hip fracture were found like history of COPD, dementia, and malnutrition, which makes it likely that those patients with pathologies that decrease physical activity or food intake can impact in an important way the appearance of osteoporosis. One of the most important contributions of this study is the identification of in-hospital complication (pneumonia), which should be actively monitored in these patients. References: [1]Falaschi P (Paolo), Marsh DR. Orthogeriatrics. Springer; 2017. [2]Cooper C, Campion G, Melton LJ. Hip fractures in the elderly: A world-wide projection. Osteoporos Int. 1992 Nov;2(6):285–9. [3]Mohd-Tahir NA, Li SC. Economic burden of osteoporosis-related hip fracture in Asia: a systematic review. Vol. 28, Osteoporosis International. Springer London; 2017. p. 2035–44. [4]Solimeo SL, Mccoy K, Reisinger HS, Adler RA, Sarrazin MV. Factors Associated With Osteoporosis Care of Men Hospitalized for Hip Fracture: A Retrospective Cohort Study. 2019; Disclosure of Interests: None declared