tbuckley/cabot-search huggingface dataset:
Language impairment in adults with end-stage liver disease: application of natural language processing towards patient-generated health records
Authors: Lindsay K. Dickerson, Masoud Rouhizadeh, Yelena Korotkaya, Mary Grace Bowring, Allan B. Massie, Mara A. McAdams-Demarco, Dorry L. Segev, Alicia Cannon, Anthony L. Guerrerio, Po-Hung Chen, Benjamin N. Philosophe, Douglas B. Mogul
Journal: npj Digital Medicine (2019)

End-stage liver disease (ESLD) is associated with cognitive impairment ranging from subtle alterations in attention to overt hepatic encephalopathy that resolves after transplant. Natural language processing (NLP) may provide a useful method to assess cognitive status in this population. We identified 81 liver transplant recipients with ESLD (4/2013-2/2018) who sent at least one patient-to-provider electronic message pre-transplant and post-transplant, and matched them 1:1 to "healthy" controls-who had similar disease, but had not been evaluated for liver transplant-by age, gender, race/ethnicity, and liver disease. Messages written by patients pre-transplant and post-transplant and controls was compared across 19 NLP measures using paired Wilcoxon signed-rank tests. While there was no difference overall in word length, patients with Model for End-Stage Liver Disease Score (MELD) ≥ 30 (n = 31) had decreased word length in pre-transplant messages (3.95 [interquartile range (IQR) 3.79, 4.14]) compared to post-transplant (4.13 [3.96, 4.28], p = 0.01) and controls (4.2 [4.0, 4.4], p = 0.01); there was no difference between post-transplant and controls (p = 0.4). Patients with MELD ≥ 30 had fewer 6+ letter words in pre-transplant messages (19.5% [16.4, 25.9] compared to post-transplant (23.4% [20.0, 26.7] p = 0.02) and controls (25.0% [19.2, 29.4]; p = 0.01). Overall, patients had increased sentence length pre-transplant (12.0 [9.8, 13.7]) compared to post-transplant (11.0 [9.2, 13.3]; p = 0.046); the same was seen for MELD ≥ 30 (12.3 [9.8, 13.7] pre-transplant vs. 10.8 [9.6, 13.0] post-transplant; p = 0.050). Application of NLP to patient-generated messages identified language differences-longer sentences with shorter words-that resolved after transplant. NLP may provide opportunities to detect cognitive impairment in ESLD.
Oral Fludarabine and Intravenous Rituximab (FR) for Chronic Lymphocytic Leukemia (CLL): Long Term Outcomes and Secondary Malignancies in 673 Patients Treated in British Columbia (BC)
Authors: Elysha Vanderveer, Steven J.T. Huang, Helene Bruyere, Tanya Gillan, Charles H. Li, Khaled Ramadan, Diego Villa, David W. Scott, Kerry J Savage, Joseph M Connors, Laurie H Sehn, Cynthia L Toze, Alina S Gerrie
Journal: Blood (2019)
Troponins and brain natriuretic peptides for the prediction of cardiotoxicity in cancer patients: a meta‐analysis
Authors: Lars Michel, Raluca I. Mincu, Amir A. Mahabadi, Stephan Settelmeier, Fadi Al‐Rashid, Tienush Rassaf, Matthias Totzeck
Journal: European Journal of Heart Failure (2019)

Abstract Aims Cardiac biomarkers are a mainstay in diagnosis of cardiovascular disease but their role in cardio‐oncology has not yet been systematically evaluated. This meta‐analysis aims to determine whether cardiac troponins and (N‐terminal pro) brain natriuretic peptide (BNP/NT‐proBNP) predict cancer therapy‐related left ventricular (LV) dysfunction. Methods and results Scientific databases were searched for studies that assessed troponins or BNP/NT‐proBNP in adult patients undergoing cancer therapy. Data from 61 trials with 5691 patients were included. Cancer therapy was associated with an increase in troponin levels [odds ratio (OR) 14.3, 95% confidence interval (CI) 6.0–34.1; n = 3049]. Patients with elevated troponins receiving chemotherapy or human epidermal growth factor receptor 2 inhibitor therapy were at higher risk for LV dysfunction (OR 11.9, 95% CI 4.4–32.1; n = 2163). Troponin had a negative predictive value of 93%. Mean BNP/NT‐proBNP levels were increased in patients post‐treatment (standardized mean difference 0.6, 95% CI 0.3–0.9; n = 912), but the available evidence did not consistently indicate prediction of LV dysfunction (OR 1.7, 95% CI 0.7–4.2; n = 197). β‐blocker and angiotensin‐converting enzyme inhibitor therapy to mitigate cardiotoxicity during cancer therapy was associated with a decline in serum troponins (OR 4.1, 95% CI 1.7–9.8; n = 466). Conclusion Elevated troponin levels predict LV dysfunction in patients receiving cancer therapy. Assessment of troponin levels may qualify as a screening test to identify patients who require referral to cardio‐oncology units and benefit from preventive strategies. Further evidence is required for both biomarkers.
Smoking and death
Authors: R. Saracci
Journal: BMJ (1995)

and other details of the protocol.The effect of this adjustment was to reduce our estimated increase in mean dose-response ratio between 1982 and 1992.Until Booth and colleagues publish the details of their methods and their data, and until clinical data on the practical effects of differences between nebulisers are available, we suggest that our method of adjusting for methodological differences on the basis of our own epidemiological data was the most accurate adjustment that could be made.Using that adjustment, we found that the level of airway responsiveness had increased between 1982 and 1992 in both study regions.This finding, which supported our conclusions that the children studied in 1992 had a higher prevalence of airway hyperresponsiveness than the children studied in 1982, is consistent with other Australian studies that have reported a significant increase in the prevalence and severity of asthma.3
Integrative Analysis of FISH, Transcriptomics and Mutational Status Predicts Responsiveness to Novel Agents in Multiple Myeloma
Authors: Cecilia Bonolo De Campos, Caleb K Stein, Nathalie Meurice, Laura Ann Bruins, Joachim L Petit, Alysia N Polito, Gregory J Ahmann, Shulan Tian, P. Leif Bergsagel, Esteban Braggio, A. Keith Stewart
Journal: Blood (2019)
Recurrent Intracranial Hemorrhage and Venous Thromboembolism Following Initial Intracranial Hemorrhage in Patients with Brain Tumors on Anticoagulation
Authors: Brian J. Carney, Erik J. Uhlmann, Maneka Puligandla, Charlene Mantia, Griffin M. Weber, Donna S Neuberg, Jeffrey I. Zwicker
Journal: Blood (2019)
Functional Characterization of Gamma Delta T Cells and Allogeneic Activated NK Cells As Effector Cells for Tafasitamab (MOR208)
Authors: Jung Hyun Her, Dominik Pretscher, Sungyoo Cho, Yu-Kyeong Hwang, Timm Hoeres, Rainer Boxhammer, Stefan Steidl, Maria Patra, Juergen Schanzer, Jan Endell
Journal: Blood (2019)
A Phase I Study Evaluating the Safety and Persistence of Allorestricted WT1-TCR Gene Modified Autologous T Cells in Patients with High-Risk Myeloid Malignancies Unsuitable for Allogeneic Stem Cell Transplantation
Authors: Emma C Morris, Rita Tendeiro-Rego, Rachel Richardson, Thomas A Fox, Francesca Sillito, Angelika Holler, Sharyn Thomas, Shao-An Xue, Irma Alicia Martínez-Dávila, Emma Nicholson, Mandana Ahmadi, Judith King, Panagiotis Kottaridis, Ronjon Chakraverty, Kirsty Thomson, Stephen Robinson, Andres E. Virchis, Asim Khwaja, Michelle Quaye, Hong Zhan, Waseem Qasim, Nourredine Himoudi, Jacqueline Barry, Natalie Mount, Terri Gaskell, Michaela Sharpe, Shannon M Inman, Kurt C. Gunter, Hans Stauss
Journal: Blood (2019)
Correlative Analyses of Patient and Clinical Characteristics Associated with Efficacy in Tisagenlecleucel-Treated Relapsed/Refractory Diffuse Large B-Cell Lymphoma Patients in the Juliet Trial
Authors: Jason R. Westin, Constantine S. Tam, Peter Borchmann, Ulrich Jaeger, Joseph P. McGuirk, Harald Holte, Edmund K. Waller, Samantha Jaglowski, Michael R. Bishop, Charalambos Andreadis, Stephen Ronan Foley, Isabelle Fleury, P Joy Ho, Stephan Mielke, Takanori Teshima, Stephen J Schuster, Veronika Bachanova, Richard T. Maziarz, Koen Van Besien, Koji Izutsu, Marie Jose Kersten, John M. Magenau, Nina D. Wagner-Johnston, Koji Kato, Paolo Corradini, Xia Han, Ranjan Tiwari, Sergei Agoulnik, Lamis K. Eldjerou, Lida Bubuteishvili Pacaud, Gilles A. Salles
Journal: Blood (2019)
Excess Serine from the Microenvironment Caused the Impaired Megakaryopoiesis and Thrombocytopia in Multiple Myeloma
Authors: Chunmei Kuang, Meijuan Xia, Gang An, Cuicui Liu, Dan Wu, Pei Su, Jingyu Zhang, Jiliang Xia, Jiaojiao Guo, Xuan Wu, Wei Jia, Lugui Qiu, Wen Zhou, Jiaxi Zhou
Journal: Blood (2019)
Carbon footprint impact of the choice of inhalers for asthma and COPD
Authors: Christer Janson, Richard Henderson, Magnus Löfdahl, Martin Hedberg, Raj Sharma, Alexander J K Wilkinson
Journal: Thorax (2019)

In the 1990s, metered dose inhalers (MDIs) containing chlorofluorocarbons were replaced with dry-powder inhalers (DPIs) and MDIs containing hydrofluorocarbons (HFCs). While HFCs are not ozone depleting, they are potent greenhouse gases. Annual carbon footprint (CO 2 e), per patient were 17 kg for Relvar-Ellipta/Ventolin-Accuhaler; and 439 kg for Seretide-Evohaler/Ventolin-Evohaler. In 2017, 70% of all inhalers sold in England were MDI, versus 13% in Sweden. Applying the Swedish DPI and MDI distribution to England would result in an annual reduction of 550 kt CO 2 e. The lower carbon footprint of DPIs should be considered alongside other factors when choosing inhalation devices.
Transcranial Doppler Velocities Conversion Rate Based on Increasing Hemoglobin Concentration: Analysies from the SCCRIP Cohort Study
Authors: Jeremie H. Estepp, Ze Cong, Irene Agodoa, Guolian Kang, Juan Ding, M. Beth McCarville, Jane S. Hankins, Winfred Wang
Journal: Blood (2019)
Treatment Sequences and Outcomes of Patients with CLL Treated with Venetoclax and Other Novel Agents Post Introduction of Novel Therapies
Authors: Anthony R. Mato, Kavita Sail, Maryam Sarraf Yazdy, Brian T. Hill, Mazyar Shadman, Beenish S Manzoor, Hande H. Tuncer, John N. Allan, Chaitra S. Ujjani, Simon Sharmokh, Daniel Dingfeng Jiang, German Pena, Thomas Marshall, Jacqueline Nielsen, Paul M. Barr, Jennifer R. Brown, Anna Schuh, Toby A. Eyre, William G. Wierda, Alan Skarbnik, Lindsey E. Roeker, Rajat Bannerji, James M. Pauff, Stephen J. Schuster, George A Follows, Bruce D. Cheson, Barbara F. Eichhorst, Danielle M. Brander, Irina Pivneva, Nicole Lamanna
Journal: Blood (2019)
Radiological Findings By Magnetic Resonance (MRI) and Arteriography (MRA) Brain Imaging Compared to Neurological, Stroke and TCD Assessment in Children with Sickle Cell Anemia in Uganda
Authors: Amelia Boehme, Richard Idro, Deogratias Munube, Paul Bangirana, Ezekiel Mupere, Robert Opoka, Michael Kawooya, Samson K. Lubowa, Angela Lignelli, Philip Kasirye, Philip LaRussa, Nancy S. Green, Frank Minja
Journal: Blood (2019)
SUBACUTE BACTERIAL ENDOCARDITIS
Authors: H. J. Starling
Journal: BMJ (1918)

WITHIN a comparatively sliort time five cases of bacterial endocarditis, forming an unusual group, liave been ad- mitted to this hospital.These cases do not belong to that type of ulcerative or malignant endocarditis witlh tlhe severe pyrexia usually associated withi this disease.They ratlher demonstrate certain clharacteristics which warrant at least four of them being placed in a category togetlher; each of them is distinct, yet all possess certain features in common.I propose, therefore, to give an account of each case and subsequently to discuss briefly thle group as a whole.CASE I.Aged 33; army service seven months.He had never been able to play games at school, and subsequently only did light work as a railway clerk.He had inflammationl of the lungs at the age of 17.At the age of 31 he had rheumatic fever, and was in bed for a month.Five months ago he had a bad attack of influenza.He enlisted in June, 1917, had no training, and was sent almost at once to France, where he was employed as fore- man of an unloading squad.He never felt well while in
TMIC-30. MICROGLIA/BRAIN MACROPHAGES PROMOTE GLIOMA GROWTH BY EXPRESSING GLYCOPROTEIN NMB
Authors: Fatih Yalcin, Alice Buonfiglioli, Ibrahim Efecan Efe, Hannah Haneke, Leonard D Kuhrt, Michael Synowitz, Bernadette Nickl, Michael Bader, Helmut Kettenmann, Omar Dzaye
Journal: Neuro-Oncology (2019)

Abstract BACKGROUND Glioma-associated microglia and blood-derived macrophages (GAMs) promote tumor growth in experimental mouse glioma models. Using microarray and RNA sequencing, we have previously shown that GAMs upregulate the expression of Glycoprotein NMB/Osteoactivin (GPNMB) when compared to naïve microglia. GPNMB is a type 1 transmembrane glycoprotein expressed intracellularly under healthy conditions. Malignancies such as glioma induce a translocation into the plasma membrane where the extracellular domain can be cleaved and released. METHODS We used qRT-PCR, immunocytochemistry, Western Blot and flow cytometry to determine the cellular localization of GPNMB expression in human and mouse glioblastoma. To test the impact of microenvironment-derived GPNMB on glioma growth, we inoculated GL261 and RCAS-PDGFb glioblastoma cells into organotypic brain slices obtained from wildtype and GPNMB-/- mice. In addition, we quantified glioma growth after injection of RCAS-PDGFb cells into wildtype and GPNMB-/- mice. The soluble extracellular domain of GPNMB was used to stimulate primary human glioblastoma and RCAS-PDGFb cells in vitro. SRB assays were performed to assess proliferation. RESULTS Our data indicate that GAMs are the predominant source of GPNMB in both human and mouse glioblastoma and that the levels of expression in GAMs in the tumor microenvironment is higher than in naïve microglia. In the organotypic brain slice model we found that tumors were significantly smaller in slices derived from GPNMB-/- mice as compared to wildtype. The tumor growth in vivo was nearly completely blocked in the absence of GPNMB. Stimulation of glioma cells with the extracellular domain of GPNMB did not increase proliferation. CONCLUSION Our results show that GPNMB is predominantly expressed in GAMs of human and murine samples. Loss of GPNMB impaired tumor growth ex vivo and glioblastoma progression in vivo. GPNMB seems to play a crucial role in the pro-tumorigenic activity of microglia and blood-derived macrophages in the tumor microenvironment.
A Comprehensive Analysis of Rhoa Mutation Positive and Negative Angioimmunoblastic T-Cell Lymphomas By Targeted Deep Sequencing, Expression Profiling, and Single Cell Digital Image Analysis
Authors: Alexandra Butzmann, Kaushik Sridhar, Diwash Jangam, Jyoti Kumar, Malaya K Sahoo, Nahid Shahmarvand, Roger A Warnke, Elumalai Rangasamy, Benjamin A Pinsky, Robert S. Ohgami
Journal: Blood (2019)
Personalised Follow-up Program after Acute Phase of Treatment in Oncology/Hematology Patients Towards Early Intervention, Better Care and Quality of Life Improvement: Results from Pasca Pilot Study
Authors: Mauricette Michallet, Mohamad Sobh, Romain Buono, Solene Poirey, Isabela Pascu, Emmanuelle Nicolas-Virelizier, Souad Assaad, Amine Belhabri, Laure Lebras, Yann Guillermin, Philippe Rey, Lila Gilis, Franck E Nicolini, Stephane Morisset, Audrey Couillet, Gisele Chvetzoff, Jean-Yves Blay, Beatrice Fervers, Anne-Sophie Michallet
Journal: Blood (2019)
Evaluating the Utilization of All-Trans Retinoic Acid and Arsenic Trioxide during Consolidation Therapy for Patients Receiving Treatment for Acute Promyelocytic Leukemia
Authors: Laura A Bowers, Maho Hibino, Rebecca Garcia Hunt, Leslie Renee Ellis, Rupali Bhave, Dianna S. Howard, Susan Lyerly, Sarah Dralle, Megan Manuel, Timothy S. Pardee, Bayard L Powell
Journal: Blood (2019)
YAP and TAZ in Fibroblastic Reticular Cells Support Hematopoiesis and Retention of Lymphocytes in Lymph Nodes
Authors: Hyunsoo Cho, Yu Ri Kim, Jieun Jang, Haerim Chung, Soo-Jeong Kim, Sung Yong Choi, Bae Hosung, Ralf Adams, Burkhard Ludewig, Jin Seok Kim, June-Won Cheong, Yoo Hong Min, Gou Young Koh
Journal: Blood (2019)
Interest of a New Method for Free Plasma Heme Related Species Dosages in Sickle Cell Disease and Beta Thalassemia
Authors: Laurent Kiger, Sandia Adypagavane, Laura Bencheikh, Nicolas Hebert, Stephane Moutereau, Frédéric Galactéros, Michael Marden, Yves Beuzard, France Pirenne, Pablo Bartolucci
Journal: Blood (2019)
CMET-04. RADIOMICS FEATURES CAN DIFFERENTIATE THE EGFR MUTATION STATUS OF BRAIN METASTASES FROM NON-SMALL CELL LUNG CANCER
Authors: Yae Won Park, Sung Soo Ahn, Dongmin Choi, Hwiyoung Kim
Journal: Neuro-Oncology (2019)

Abstract BACKGROUND AND PURPOSE To assess whether radiomics features on DTI and conventional postcontrast T1-weighted (T1C) images can differentiate the epidermal growth factor receptor (EGFR) molecular status in brain metastases from non-small cell lung cancer (NSCLC). MATERIALS AND METHODS Radiomics features (n = 5046) were extracted from preoperative MRI including T1C and DTI from pathologically confirmed brain metastases of 59 patients with underlying NSCLC and known EGFR mutation status (31 EGFR wild type, 28 EGFR mutant). A subset of 4317 features (85.6%) with high stability (intraclass correlation coefficient &gt; 0.9) were selected for further analysis. After feature selection by the least absolute shrinkage and selection operator, the radiomics classifiers were constructed by various machine learning algorithms. The prediction performance of the classifier was validated by using leave-one-out cross-validation. Diagnostic performance was compared between multiparametric MRI radiomics models and single imaging radiomics models using the area under the curve (AUC) from ROC analysis. RESULTS Thirty-seven significant radiomics features (6 from ADC, 6 from fractional anisotropy [FA], 25 from T1C) were selected. The best performing multiparametric radiomics model (AUC 0.97, 95% CI 0.94–1) showed better performance than any single radiomics model using ADC (AUC 0.79, p = 0.007), FA (AUC 0.75, p = 0.001), or T1C (AUC 0.96, p = 0.678); the accuracy, sensitivity, and specificity of this model were 94.4%, 96.6%, and 92.0%, respectively. CONCLUSION Radiomics classifiers integrating multiparametric MRI parameters may be useful to differentiate the EGFR mutation status in brain metastases from lung cancer.
Abstract 16199: The Carbohydrate- and Alcohol Intakes Associated FGF21 Genotype, Change in Alcohol Consumption, and Weight Change
Authors: Hao Ma, Xiang Li, Tao Zhou, Dianjianyi Sun, Yoriko Heianza, Lu Qi
Journal: Circulation (2018)

Introduction: The association of alcohol consumption with weight change remains controversial. Fibroblast growth factor 21 (FGF21) is a metabolic regulator with multiple beneficial effects on metab...
Anticoagulation Challenges in Hematogeriatrics: Effectiveness and Safety of Direct Oral Anticoagulants Vs Vitamin k Antagonist in Elderly with Atrial Fibrillation
Authors: Desirée Campoy, Gonzalo Artaza, César A Velasquez, Tania Canals, Erik A Johansson, Katia Flores, Gabriela Bastidas, Silvia Ruiz, Gabriela S Ene, Alessandra Comai, Maricel Subira, Ramón Salinas, Jorge Sierra, Pável E Olivera
Journal: Blood (2019)
RASA3 Is Essential for Early Mammalian Hematopoiesis and Modulates ERK Signaling in Terminal Erythropoiesis
Authors: Elena C. Brindley, Raymond F. Robledo, Steven L. Ciciotte, Joel H. Graber, Yue Zhao, Emily Hartman, Julien Papoin, Lionel Blanc, Luanne L. Peters
Journal: Blood (2019)
CD20-TCB, a Novel T-Cell-Engaging Bispecific Antibody, Induces T-Cell-Mediated Killing in Relapsed or Refractory Non-Hodgkin Lymphoma: Biomarker Results From a Phase I Dose-Escalation Trial
Authors: Ann-Marie E Bröske, Ian James, Anton Belousov, Enrique Gomez, Marta Canamero, Chia-Huey Ooi, Nils Grabole, Sabine Wilson, Koorosh Korfi, Nicole A Kratochwil, Peter N Morcos, Cristiano Ferlini, Denise Thomas, Natalie Dimier, Tom Moore, Marina Bacac, Martin Weisser, Michael Dickinson
Journal: Blood (2019)
Treatment Patterns in Patients (pts) with Refractory/Relapsed Multiple Myeloma (RRMM) in Germany between 2016 and 2018
Authors: Maximilian Merz, Vishal Patel, Lucie Kutikova, Andrea Lebioda, Martina Schoehl, Lenka Kellermann, Hartmut Goldschmidt
Journal: Blood (2019)
Mutational Characteristics and Changing Pattern from Idiopathic Cytopenia of Undetermined Significance to High-Risk Myelodysplastic Syndrome Stratified By IPSS-R
Authors: Eun-Ji Choi, Young-Uk Cho, Seongsoo Jang, Chan-jeoung Park, Han-Seung Park, Jung-Hee Lee, Kyoo-Hyung Lee, Eun-Hye Hur, Nayoung Kim, Hee Jeong Ouk, Je-Hwan Lee
Journal: Blood (2019)
Cerebral Malaria in Great Britain
Authors: P. H. Willcox
Journal: BMJ (1947)

MEDICAL JOURNAl'being helped by quadriceps exercises and radiant heat.Subsequent convalescence, though slow, was uneventful.Negative investigations included stool examinations, culture of urine and 24-hour specimen for the acid-fast bacillus, x rays of the affected joints and also of the chest.Leucocyte counts in the acute stage varied between six and nine thousand cells per c.mm. (P.: 70%; L.: 25%; M.: 3%; E.: 2%).Blood culture was sterile.The patient illustrates the salient features of the disease, including the liability to sudden serous joint effusions and the subacute but self-limited course.The duration of nearly four months coincides pretty well with the cases written up by Jackson and by Wrigley (ibid., p. 199).He also appears to have been helped by sulphathiazole as were their cases.It is one of the many annoying features about medicine in India that many special investigations are not available, including the gonococcal complement fixation test, but there was no clinical doubt that this was not a case of gonococcal arthritis but of the rarer Reiter's syndrome.-Iam.
Acute Myeloid Leukemia and Antifungal Prophylaxis Era: Compliance of AML Centers, Invasive Fungal Infection (IFI) Classification, IFI Incidence and AML Outcomes from ALFA 2007- 02 Study
Authors: Mauricette Michallet, Mohamad Sobh, Stephane Morisset, Alexandre Deloire, Emmanuel Raffoux, Stephane De Botton, Denis Caillot, Sylvain Chantepie, Stephane Girault, Celine Berthon, Sarah Bertoli, Stephane Lepretre, Thibaut Leguay, Sylvie Castaigne, Jean-Pierre Marolleau, Cecile Pautas, Jean Valère Malfuson, Norbert Vey, Lauris Gastaud, Felipe Suarez, Aline Schmidt, Rémy Gressin, Caroline Bonmati, Karine Celli-Lebras, Mohamed El-Hamri, Patricia Ribaud, Herve Dombret, Xavier Thomas, Anne Bergeron
Journal: Blood (2019)
Phase II Study of the Combination of Daratumumab, Ixazomib, Pomalidomide, and Dexamethasone As Salvage Therapy in Relapsed/Refractory Multiple Myeloma: Results of a Safety Run-in Analysis
Authors: Caitlin L. Costello, Michelle Padilla, Edward D. Ball, Carolyn Mulroney
Journal: Blood (2019)
Interferon-a-2b As a Maintenance Therapy Significantly Improves Disease-Free Survival in Patients with Low-Risk Acute Myeloid Leukemia
Authors: Xiaohong Liu, Wenbing Duan, Jing Wang, Jinsong Jia, Lizhong Gong, Shen-ye Lu, Xiaosu Zhao, Ying-Jun Chang, Yue-Yun Lai, Hongxia Shi, Yu Wang, Chenhua Yan, Xiaojun Huang, Hao Jiang
Journal: Blood (2019)
Serum Creatine Kinase and Exercise
Authors: A. Vejjajiva, G. M. Teasdale
Journal: BMJ (1965)

fore in danger of being opened.The ex- posure is also difficult.After trying the above incision, I have now resorted to another.The skin is incised a few millimetres above the skin margin.The incision is therefore on the skin portion of the umbilicus.A thick white sheath is at once revealed.If this is incised horizontally with a deep cut the thick sheath gapes, and the insertion of an artery forceps will easily pick up the vein.The procedure is simple and takes only a few minutes.The incision heals well with a hardly noticeable scar.-I am, etc.,
Overall Survival in Patients with JAK2 and ASXL1 Positive Myeloproliferative Neoplasms
Authors: Murtadha Al-Khabori, Shoaib Al-Zadjali, Iman Al Noumani, Khalil Al Farsi, Salam Al-Kindi, Mohamed Al Huneini, Naglaa Fawaz, Al Lamki Sulayma, Mahdiya Pir Al Bulushi, Khalid Al Hashmi, Muna Al Tarshi, Muhanna Almusalhi
Journal: Blood (2019)