AB1025 EVALUATION OF ANXIETY AND DEPRESSION LEVELS IN PATIENTS WITH FAMILIAL MEDITERREAN FEVER
Authors: S. Ergulu Eşmen
Journal: Annals of the Rheumatic Diseases (2020)

Background: Anxiety and depression are common problems in chronic rheumatological diseases (1). Familial Mediterranean Fever (FMF) is characterized by recurrent fever and serosal inflammation attacks. Objectives: The aim of the study was to evaluate the levels of anxiety and depression in patients diagnosed with FMF, and to examine its relationship with drug compliance and attack frequency. Methods: Sixty female patients aged 18 years or older who were consecutively admitted to the rheumatology outpatient clinic and diagnosed as FMF according to the Tel-Hashomer Classification criteria were included. Patients’ age, gender, body mass index (BMI), educational status, disease duration, drugs used and frequency of attacks were recorded. Beck anxiety scale and Beck depression scale were used to determine the level of anxiety and depression. Results: Sixty female patients with a mean age of 32.03 ± 10.03 and an mean disease duration of 9 ± 6.9 years were included in the study. The patients were divided into minimal, mild, moderate and severe according to their anxiety level. According to the level of anxiety, minimal anxiety was observed in 18 (30%), mild 9 (15%), moderate 12 (20%) and severe anxiety in 10 (16.7%) patients. Data related to anxiety are given in table 1. The patients were divided into minimal, mild, moderate and severe depending on the level of depression. Depending on the level of depression, minimal depression was seen in 34 (56.7%), mild 13 (21.7%), moderate 8 (13.3%) and severe depression in 4 (6.7%) patients. Data related to depression are given in table 2. Table 1. Data about anxiety Minimal Mild Moderate Severe P Age (years) (mean ± SD) 30.82 ±10.7 26.22±8.5 34.42±10.2 33.4±9.7 0.28 BMI (kg/m 2 ) (mean ± SD) 25.53±5.05 19.88±2.7 25.03±4.91 26.03± 3.4 0.02 Disease duration (years) 11.93±9.6 8.67±4.0 10.5±6.7 4,89±3,7 0.13 Marriatal status (Married) 13 (70) 2 (22.2) 10 (83.3) 9 (90) 0,06 Child status (%)(having child) 12 (70.6) 1 (11.1) 8 (72.2) 0,006 Time of the last attack (%) 0,72 2 weeks ago 2 (11.8) 2 (22.2) 4 (33.3) 4 (50) 3 months ago 4 (23.5) 1 (11.1) 2 (16.7 - &gt;6 months 7 (41.2) 4 (44.4) 4 (33.3) 3 (37.5) Table 2. Data about depression Minimal Mild Moderate Severe P Age (years) (mean ± SD) 32.79±9.89 28.83±8.93 32.63±10.5 36.5±14.3 0.61 BMI (kg/m 2 ) (mean ± SD) 25.68±5.09 22.06±3.2 23.81±4.33 26.35±2.8 0.076 Disease duration (years) 10.52±8.06 8.5±4.6 8.67±4.6 1.5±1 &lt;0.00 Marriatal status (Married) 25 (73.5) 8 (61.5) 7 (87.5) 3 (75) 0,63 Child status (%)(having child) 23 (71.9) 5 (38.5) 7 (87.5) 3 (75) 0,08 Time of the last attack (%) 0,94 2 weeks ago 6 (18.2) 2 (16.7) 2 (28.6) 2 (50) 3 months ago 8 (24.2) 1 (8.3) 1 (14.3) 1 (25) &gt;6 months 12(36.4) 5 (41.7) 2 (28.6) 1 (25) Conclusion: In the case of a chronic disease such as FMF, which has a younger patient population than other rheumatic diseases, anxiety and depression should be evaluated during routine outpatient clinic administration and psychiatric support should be provided if necessary. References: [1]Deger SM, Ozturk MA, Demirag MD, et al. Health-related quality of life and its associations with mood condition in Familial Mediterranean Fever patients. Rheumatol Int. 2011;31(5):623-8. Disclosure of Interests: None declared