SAT0212 ASSOCIATION BETWEEN SELF-EFFICACY AND HEALTH-RELATED QUALITY OF LIFE IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS
Authors: Paola Alejandra Zeña Huancas, Cristina Reategui Sokolova, Rocio Gamboa Cardenas, Mariela Medina Chinchon, Francisco Zevallos Miranda, Victor Pimentel Quiroz, Claudia Elera-Fitzcarrald, Jose Alfaro Lozano, Cesar Pastor Asurza, Risto Perich Campos, Zoila Rodriguez Bellido, Graciela S. Alarcon, Manuel F. Ugarte-Gil
Journal: Annals of the Rheumatic Diseases (2019)

<h3>Background:</h3> Self-efficacy for managing chronic conditions assesses the confidence a person has on the ability of successfully perform specific tasks related to a chronic condition in several different situations. Self-efficacy is considered one of the most important modifiable factors in educational interventions that enhance Systemic Lupus Erythematosus (SLE) patients' mental health status. Low disease self-efficacy is associated with SLE morbidity.<sup>1</sup> <h3>Objectives:</h3> To determine the association of several domains of self-efficacy for managing chronic conditions and health-related quality of life (HRQoL) in SLE patients. <h3>Methods:</h3> We evaluated patients with SLE from a single center cohort between October 2018 and January 2019. Using a standard protocol, we evaluated demographic characteristics, clinical manifestations and treatment. Self-efficacy was measured with the Spanish version of the Self-Efficacy for Managing Chronic Disease Scale (PROMIS Short Form v1.0) which include six domains: general self-efficacy, managing emotions, managing symptoms, managing daily activities, managing social interactions, managing medications and treatment. A score of 50 is the average for the US general populations with a standard deviation of 10 (such values are not available for Peruvian or Latin American populations). HRQoL was measured with the LupusQoL, disease activity was ascertained with the Systemic Lupus Erythematosus Disease Activity Index – 2K (SLEDAI-2K), and damage with the Systemic Lupus International Collaborating Clinics (SLICC)/American College of Rheumatology (ACR) damage index (SDI). The associations between self-efficacy (six domains) and each domain of LupusQoL were examined using linear regression models, adjusted by gender, age at diagnosis, socioeconomic status, educational level, SLEDAI-2K, SDI, prednisone daily dose, and antimalarial and immunosuppressant use. <h3>Results:</h3> A total of 60 patients fit the inclusion criteria. Of them, 54 (90.0%) were female, their mean (SD) age at diagnosis was 37.3 (13.4) years, disease duration was 9.2 (7.2) years. The HRQoL domains most affected were the following: burden to others, intimate relationships, and body image. Self-efficacy was lower than the expected for the general population ranging between 43.1 and 48.6. The six domains of self-efficacy were positively associated with the majority of the domains of HRQoL, as depicted in Table 1. <h3>Conclusion:</h3> Low disease self-efficacy in the management of SLE negatively correlated with HRQoL. The impact of the improvement of self-efficacy in the HRQoL should be evaluated prospectively. <h3>Reference</h3> [1] Mazzoni D, et al. Health-related quality of life in systemic lupus erythematosus: a longitudinal study on the impact of problematic support and self-efficacy. Lupus. 2017 Feb; 26(2):125-131. <h3>Disclosure of Interests:</h3> None declared