tbuckley/cabot-search huggingface dataset:
IMPACT OF “MOTION TRAINING” ON ACQUIRING CANNULATION SKILLS FOR NOVICE ENDOSCOPISTS TRAINING ON A VALIDATED MECHANICAL ERCP SIMULATOR: INTERIM ANALYSIS FROM A RANDOMIZED CONTROL TRIAL
Authors: C Pușcașu, I Boškoski, G Costamagna, S Perretta, L Fuccio, N Rustemovic, M Cavlina, B Orlandini, A Benguș, A Voiosu, B Mateescu, T Voiosu
Journal: Endoscopy (2020)

Aims ERCP training remains a sensitive issue, with current data showing that traditional training methods, based on a hands-on, master-disciple paradigm, fall short of producing competent trainees. We aimed to evaluate whether a novel approach to training might improve the learning curve for novice endoscopists training in ERCP.
CC-CLEAR (COLON CAPSULE CLEANSING ASSESSMENT AND REPORT): A NEW APPROACH TO EVALUATE THE QUALITY OF BOWEL PREPARATION IN THE CAPSULE COLONOSCOPY
Authors: R Magalhaes, C Arieira, B Rosa, MJ Moreira, J Cotter
Journal: Endoscopy (2020)

Aims An adequate colon cleansing is paramount to rely on colon capsule reported findings. Thus, we should strive for high intra and inter observer agreement for the evaluation of colon cleansing. The commonly used colon capsule cleansing grading scales rely on subjective parameters and lack proper interobserver agreement. We aim to validate a new grading scale for the evaluation of colon capsule cleansing.
Infection Risk with Nitrofurazone-Impregnated Urinary Catheters in Trauma Patients
Authors: Jakob Stensballe, Michael Tvede, Dagnia Looms, Freddy Knudsen Lippert, Benny Dahl, Else Tønnesen, Lars Simon Rasmussen
Journal: Annals of Internal Medicine (2007)

Indwelling urinary catheters increase risk for bacteriuria and clinically significant urinary tract infection. In a randomized trial, Stensballe and colleagues found that trauma patients who receiv...
DANIS STENT: A CASE SERIES OF PATIENTS WITH REFRACTORY OESOPHAGEAL VARICEAL BLEEDING
Authors: MM Saeidinejad, N Prasad, R Keld, CS Lee
Journal: Endoscopy (2020)

Aims To assess the safety and efficacy of DANIS self-expandable metal stent (SEMS) in treatment of refractory variceal oesophageal bleeding.
Azathioprine plus Prednisone Compared with Prednisone Alone in the Treatment of Systemic Lupus Erythematosus
Authors: Bevra H. Hahn, Owen S. Kantor, C. Kirk Osterland
Journal: Annals of Internal Medicine (2020)

Abstract A prospective, randomized drug trial compared prednisone (60 mg per day initially) to azathioprine (3 to 4 mg/kg of body weight · day initially) plus prednisone in 24 patients with life-th...
NON-EXPOSURE SIMPLE SUTURING ENDOSCOPIC FULL-THICKNESS RESECTION (NESS-EFTR) WITH SENTINEL BASIN DISSECTION IN PATIENTS WITH EARLY GASTRIC CANCER, SENORITA 3 PILOT STUDY
Authors: CG Kim, BW Eom, MC Kook, HM Yoon, KW Ryu, YW Kim, JY Rho, YI Kim, JY Lee, IJ Choi
Journal: Endoscopy (2020)

Aims Recently, non-exposure simple suturing endoscopic full-thickness resection (NESS-EFTR) was developed, and this procedure was designed to prevent tumor exposure to the peritoneal cavity. The aim of this study was to evaluate the feasibility of NESS-EFTR with sentinel basin dissection for early gastric cancer.
COMBINED EUS-ELASTOGRAPHY (EUS-E) AND CONTRAST-ENHANCED HARMONIC EUS (CH-EUS) IMPROVES DIFFERENTIAL DIAGNOSIS BETWEEN BENIGN AND MALIGNANT LYMPH NODES - A PROSPECTIVE STUDY
Authors: A Lisotti, A Cominardi, M Serrani, S Lega, S Di Girolamo, F Poli, L Scopece, M Puccetti, A Maestri, P Fusaroli
Journal: Endoscopy (2020)

Aims To evaluate the diagnostic performance of contrast-enhanced EUS(CH-EUS) and elastography(EUS-E) combination in the differential diagnosis(DD) between benign and malignant lymph nodes(LN).
Cardiac Transplantation in Man
Journal: JAMA (1968)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Post Contusion Breast Hematoma Mimicking Malignancy on FDG PET/CT
Authors: Daniel Levin, Sophie Lantsberg, Maia Rosenthal Giladi, Dina Ezroh Kazap, Nir Hod
Journal: Clinical Nuclear Medicine (2020)

Abstract A 32-year-old woman was treated for breast carcinoma. Posttreatment FDG PET/CT scan revealed complete response, but in the contralateral breast, unexpected incidental intense FDG uptake was seen with a differential diagnosis of both malignant and benign causes. Medical history revealed recent breast contusion. The lesion was further evaluated by mammogram and ultrasound, which were compatible with deep breast bruise. Histopathology showed no malignancy. Subsequent FDG PET/CT study showed breast uptake normalization. This case shows that postcontusion breast hematoma can cause a potential pitfall mimicking breast malignancy on FDG PET/CT.
COLONIC PERFORATION AFTER ROUTINE BIOPSY IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE
Authors: E Klenske, A Hartmann, R Atreya, M Neurath, T Rath
Journal: Endoscopy (2020)

Here we present two cases of colonic perforation after routine biopsy in patients with long-standing inflammatory-bowel-diseases. In vivo histology using a latest generation endocytoscope revealed crypt distension and deformity along with inflammatory cell infiltrates. After biopsy in the sigmoid colon with a standard biopsy forceps, small perforations occured, which were successfully managed by OTS-clipping. Conventional histology additionally showed fibrosis of the lamina propria along with atrophy of the entire colonic wall. Our cases demonstrate that biopsy-related perforation can occur in long-staining IBD without significant disease activity. Therefore, in vivo histology might help to minimize perforation risks in IBD patients.
ENDOSCOPIC ULTRASONOGRAPHY-GUIDED GASTROENTEROSTOMY IS A PROMISING ENDOSCOPIC TECHNIQUE FOR PALLIATIVE TREATMENT OF GASTRIC OUTLET OBSTRUCTION. A MULTICENTER NATIONAL EXPERIENCE
Authors: R Sanchez-Aldehuelo, ER de Santiago, SP Herce, JC Súbtil Íñigo, JRA Tormo, FGH Lladó, AS Yagüe, JG Soler, AR Ortega, CG Argente, JRF Olcina, A Albillos, E Vázquez-Sequeiros
Journal: Endoscopy (2020)

Aims Background Endoscopic ultrasound (EUS)-guided gastrojejunostomy (EUS-GJ) is an alternative for treating gastric outlet obstruction (GOO) in expert centers. It remains unknown if these results may be reproducible in less experienced institutions.
DISCONNECTED PANCREATIC DUCT SYNDROME (DPDS): ENDOSCOPIC REPAIR BY MEANS OF STAGED EUS-GUIDED PANCREATICO-GASTROSTOMY (EUS-PG) COMBINED WITH ERCP
Authors: R Sánchez-Ocaña, G Salazar, C Chavarria Herbozo, C Chavarría, J Garcia Alonso, C de la Serna Higuera, M Perez-Miranda
Journal: Endoscopy (2020)

Introduction DPDS requires distal pancreatectomy to avoid persistent/recurrent collections/pancreatitis/fistulas. We describe endoscopic reconnection, novel alternative.
Epileptic seizure discharges in patients after open chamber cardiac surgery—a prospective prevalence pilot study using continuous electroencephalography
Authors: Marlene Tschernatsch, Martin Juenemann, Fouad Alhaidar, Jasmin El Shazly, Marius Butz, Marco Meyer, Tibo Gerriets, Markus Schönburg, Patrick Schramm
Journal: Intensive Care Medicine (2020)

Patients undergoing cardiac surgery often develop delirium which increases the risk of postoperative morbidity and leads to a reduced quality of life. Retrospective studies show a higher incidence of delirium in patients with seizures. However, these studies do not systematically detect subclinical seizures, so the incidence of seizures after cardiac surgery remains speculative. The objective of this study is to determine the prevalence of electrographic seizures after elective open-chamber cardiac surgery. This prospective, blinded, monocentric, observational study investigated patients scheduled for elective open-chamber valve reconstruction or replacement. Anaesthesia, surgery and postoperative treatment were standardized and not influenced by the presented observation. After surgery, all patients arrived at the ICU, and EEG monitoring started within the first hour. EEG recording was continuously performed for up to 24 h, and the results were independently analysed by two blinded EEG board-certified neurologists. 100 patients were included. Abnormal EEG patterns were present in 33% of patients, and 9% of all patients showed electrographic seizures. The main EEG activity at the beginning of each recording was suppressed or showed a burst-suppression pattern, and at the end of recording, all patients had an alpha/theta rhythm. An association between electrographic seizures and delirium was found (pχ2 < 0.01). This study reveals a surprisingly high incidence of abnormal EEG patterns and electrographic seizures in patients undergoing open-chamber cardiac surgery. As electrographic seizures are associated with the incidence of delirium, this finding is a relevant phenomenon in the post-cardiac surgery ICU population.
Z POEM FOR ZENKER´S DIVERTICULUM: A SINGLE CENTRE DATA OF 16 CASES
Authors: P Desai, M Kabrawala, C Patel, P Kalra, R Prajapati, N Patel
Journal: Endoscopy (2020)

Aims We studied 16 cases of Zenker’s diverticulum causing dysphagia and regurgitation treated with Z POEM. Traditionally septotomy has recurrence rate of around 20 to 30%%. Hence we attempted to see if Z POEM reduces recurrence.
COVID-19 infection in a northern-Italian cohort of systemic lupus erythematosus assessed by telemedicine
Authors: Emanuele Bozzalla Cassione, Giovanni Zanframundo, Alessandro Biglia, Veronica Codullo, Carlomaurizio Montecucco, Lorenzo Cavagna
Journal: Annals of the Rheumatic Diseases (2020)

The COVID-19 pandemic deeply affected northern-Italian regions.1 Lombardy and Emilia-Romagna had the highest cumulative incidence with 627.1 and 470.53 cases/100 000 inhabitants respectively on 16 April 2020 according to Italian ‘Istituto Superiore di Sanita’ (ISS). While a mild course has been reported in patients with chronic arthritis treated with targeted immunosuppressive agents,2 few and controversial data are available about COVID-19 in systemic lupus erythematosus (SLE).3 4 To this purpose, since 6 April 2020, given the mobility restriction imposed nationwide, we initiated a telemedicine project aimed at ensuring regular follow-up, starting from SLE patients.5 During the visit, we conducted a survey to investigate any COVID-19 related symptoms that occurred since 15 February 2020 and the results of available nasopharyngeal swabs. The survey was addressed to patients coming from Lombardy and Emilia-Romagna. We evaluated 165 patients (112 females, 84%, median age 52.5 years, range 25–81; median disease duration 13 years, range 1–53). Among them, 127 (77%) were on hydroxychloroquine …
IMPROVING QUALITY IN COLON CAPSULE ENDOSCOPY; EFFECTS OF DIFFERENT BOWEL PREPARATION REGIMENS
Authors: M Syafiq Ismail, S Semenov, S Sihag, N Breslin, A O’Connor, B Ryan, D McNamara
Journal: Endoscopy (2020)

Aims In selected patients, Colon Capsule Endoscopy (CCE) has been recommended by ESGE as an alternative to colonoscopy. The effect of different bowel preparation regimens on Completion Rate (CR) and Bowel Cleansing (BC) is inconclusive.
Altered Lymphatic Vessel Anatomy and Markedly Diminished Lymph Clearance in Affected Hands of Patients With Active Rheumatoid Arthritis
Authors: Richard D. Bell, Homaira Rahimi, H. Mark Kenney, Alicia A. Lieberman, Ronald W. Wood, Edward M. Schwarz, Christopher T. Ritchlin
Journal: Arthritis & Rheumatology (2020)

Objective To assess differences between lymphatic function in the affected hands of rheumatoid arthritis ( RA ) patients with active synovitis and that of healthy controls, using indocyanine green ( ICG ) dye and near‐infrared ( NIR ) imaging. Methods NIR imaging of the hands of 8 patients with active RA and 13 healthy controls was performed following web space injection of 0.1 ml of 100 μ M ICG . The percentage of ICG retention in the web spaces was determined by NIR imaging at baseline and at 7 days (±1 day) after the initial injections; image analysis provided contraction frequency. ICG + lymphatic vessel ( LV ) length and branching architecture were assessed. Results Retention of ICG in RA hands was higher compared to controls ( P &lt; 0.01). The average contraction frequency of ICG + LV s in RA patients and in controls did not differ (mean ± SD 0.53 ± 0.39 contractions/minute versus 0.51 ± 0.35 contractions/minute). Total ICG + LV length in RA hands was lower compared to healthy controls (58.3 ± 15.0 cm versus 71.4 ± 16.1 cm; P &lt; 0.001), concomitant with a decrease in the number of ICG + basilic LV s in the hands of RA patients ( P &lt; 0.05). Conclusion Lymphatic drainage in the hands of RA patients with active disease was reduced compared to controls. This reduction was associated with a decrease in total length of ICG + LV s on the dorsal surface of the hands, which continued to contract at a similar rate to that observed in controls. These findings provide a plausible mechanism for exacerbation of synovitis and joint damage, specifically the accumulation and retention of inflammatory cells and catabolic factors in RA joints due to impaired efferent lymphatic flow. NIR / ICG imaging of RA hands is feasible and warrants formal investigation as a primary outcome measure for arthritis disease severity and/or persistence in future clinical trials.
PREDICTORS OF STENT DYSFUNCTION IN PATIENTS WITH BILATERAL METAL STENTS FOR MALIGNANT HILAR OBSTRUCTION
Authors: TJ Song, H So, SW Ko, JS Hwang, D Oh, DH Park, SS Lee, DW Seo, SK Lee, MH Kim
Journal: Endoscopy (2020)

Aims For unresectable hilar obstruction, restoring and maintaining biliary ductal patency is a key to improved survival and quality of life. Endoscopic placement of stents is now a mainstay of the treatment, and bilateral stenting is effective for biliary decompression. This study’s aim was to find out clinical outcomes of bilateral self-expandable metal stents (SEMS) and clinical predictors of stent dysfunction in patients with malignant hilar obstruction.
Model of a Queuing Approach for Patient Accrual in Phase 1 Oncology Studies
Authors: Paul H. Frankel, Vincent Chung, Joseph Tuscano, Tanya Siddiqi, Sagus Sampath, Jeffrey Longmate, Susan Groshen, Edward M. Newman
Journal: JAMA Network Open (2020)

<h3>Importance</h3> Phase 1 cancer studies, which guide dose selection for subsequent studies, are almost 3 times more prevalent than phase 3 studies and have a median study duration considerably longer than 2 years, which constitutes a major component of drug development time. <h3>Objective</h3> To discern a method to reduce the duration of phase 1 studies in adult and pediatric cancer studies without violating risk limits by better accommodating the accrual and evaluation process (or queue). <h3>Design</h3> The process modeled, the phase 1 queue (IQ), includes patient interarrival time, screening, and dose-limiting toxicity evaluation. For this proof of principle, the rules of the 3 + 3 and rolling 6 phase 1 designs were modified to improve patient flow through the queue without exceeding the maximum risk permitted in the parent designs. The resulting designs, the IQ 3 + 3 and the IQ rolling 6, were each compared with their parent design by simulations in 12 different scenarios. <h3>Main Outcomes and Measures</h3> (1) The time from study opening to determination of the maximum tolerated dose (MTD), (2) the number of patients treated to determine the MTD, and (3) the association of the design with the dose selected as the MTD. <h3>Results</h3> Based on 800 simulations, for all 12 scenarios considered, the IQ 3 + 3 and the IQ rolling 6 designs were associated with reduced expected study durations compared with the parent design. The expected IQ 3 + 3 reduction ranged from 1.6 to 10.4 months (with 3.7 months for the standard scenario), and the expected reduction associated with IQ rolling 6 ranged from 0.4 to 10.5 months (with 3.4 months for the standard scenario). The increase in the mean number of patients treated in the IQ 3 + 3 compared with the 3 + 3 ranged from 0.6 to 3.2 patients. No increase in the number of patients was associated with the IQ rolling 6 compared with the rolling 6 design. The probability of selecting a dose level as the MTD changed by less than 3% for all dose levels and scenarios in both parent designs. <h3>Conclusions and Relevance</h3> This study found that IQ designs were associated with reduced mean duration of phase 1 studies compared with their parent designs without changing the risk limits or MTD selection operating characteristics. These approaches have been successfully implemented in both hematology and solid tumor phase 1 studies.
The impact of different antibiotic treatment regimens on mortality in <i>Mycobacterium avium</i> complex pulmonary disease: a population-based cohort study
Authors: Sarah K. Brode, Hannah Chung, Michael A. Campitelli, Jeffrey C. Kwong, Rinku Sutradhar, Alex Marchand-Austin, Kevin L. Winthrop, Frances B. Jamieson, Theodore K. Marras
Journal: European Respiratory Journal (2020)

Evidence-based guidelines recommend the combination of macrolide–ethambutol–rifamycin as first-line treatment for Mycobacterium avium complex pulmonary disease (MAC-PD) [1]. Whether this regimen results in improved survival is unknown. No significant difference in mortality among patients treated with different antibiotic regimens for Mycobacterium avium pulmonary disease <https://bit.ly/3abXjDJ> We thank IMS Brogan Inc. for use of their Drug Information Database.
Thalidomide in the Treatment of the Mucocutaneous Lesions of the Behcet Syndrome
Authors: Vedat Hamuryudan, Cem Mat, Sebahattin Saip, Yilmaz Ozyazgan, Aksel Siva, Sebahattin Yurdakul, Kai Zwingenberger, Hasan Yazici
Journal: Annals of Internal Medicine (1998)

Background: Recurrent oral and genital ulcers are the most frequent problem in the management of the Behcet syndrome. Uncontrolled experience suggests that thalidomide may help prevent recurrences ...
Transient Ischemic Attack
Authors: Pierre Amarenco
Journal: New England Journal of Medicine (2020)

A suspected transient ischemic attack should be evaluated urgently in a clinical setting where appropriate specialist expertise and imaging (ideally diffusion-weighted imaging) are available. Management typically includes aspirin (immediately and indefinitely, with clopidogrel for the first 21 days), evaluation to identify the cause and guide intervention as appropriate, and control of risk factors.
Duodenal Perforation due to Prophylactic Pancreatic Stent
Authors: C Loras, X Andújar
Journal: Endoscopy (2021)

An ERCP was performed in 85 years old woman due to choledocholithiasis. Precut pancreatic sphincterotomy was performed to allow biliary cannulation. A stone was removed with Fogarty balloon and plastic stent of 5cmx 5Fr was placed to prevent acute pancreatitis.
ENDOSCOPIC ULTRASOUND-GUIDED FINE-NEEDLE ASPIRATION FOR SUBEPITHELIAL LESIONS: A SINGLE CENTRE EXPERIENCE
Authors: M João, L Elvas, D Brito, M Areia, S Alves, F Taveira, S Saraiva, AT Cadime
Journal: Endoscopy (2020)

Aims Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is commonly used for obtaining tissue from gastrointestinal subepithelial lesions (SEL). However, the diagnostic accuracy of this technique ranges widely (46%-93%) depending on multiple factors. The aim of our study was to evaluate diagnostic yield of EUS-FNA of SEL and factors related to sampling adequacy.
STENT VERSUS BALLOON DILATION FOR THE TREATMENT OF DOMINANT STRICTURES IN PRIMARY SCLEROSING CHOLANGITIS: A SYSTEMATIC REVIEW AND META-ANALYSIS
Authors: M Tucci, IB Ribeiro, DTH de Moura, M Coronel, WM Bernardo, P Sakai, EGH de Moura
Journal: Endoscopy (2020)

Aims Primary sclerosing cholangitis (PSC) is a chronic fibro-inflammatory disease of the biliary system, which causes cholestatic symptoms, hepatic failure, and increases the risk of cholangiocarcinoma. Many patients with PSC presents with a dominant stricture, which can intensify the cholestatic symptoms, and endoscopic therapies are often used to maintain the patency of the biliary tract. However, the best therapeutic approach to treat dominant strictures remains unclear. This study aims to compare balloon dilation with stent placement for the treatment of dominant stricture in patients with PSC.
Deubiquitination of NLRP6 inflammasome by Cyld critically regulates intestinal inflammation
Authors: Sandip Mukherjee, Ritesh Kumar, Elviche Tsakem Lenou, Venkatesha Basrur, Dimitris L. Kontoyiannis, Fotis Ioakeimidis, George Mosialos, Arianne L. Theiss, Richard A. Flavell, K. Venuprasad
Journal: Nature Immunology (2020)
Acute Heart Failure in Multisystem Inflammatory Syndrome in Children in the Context of Global SARS-CoV-2 Pandemic
Authors: Zahra Belhadjer, Mathilde Méot, Fanny Bajolle, Diala Khraiche, Antoine Legendre, Samya Abakka, Johanne Auriau, Marion Grimaud, Mehdi Oualha, Maurice Beghetti, Julie Wacker, Caroline Ovaert, Sebastien Hascoet, Maëlle Selegny, Sophie Malekzadeh-Milani, Alice Maltret, Gilles Bosser, Nathan Giroux, Laurent Bonnemains, Jeanne Bordet, Sylvie Di Filippo, Pierre Mauran, Sylvie Falcon-Eicher, Jean-Benoît Thambo, Bruno Lefort, Pamela Moceri, Lucile Houyel, Sylvain Renolleau, Damien Bonnet
Journal: Circulation (2020)

Background: Cardiac injury and myocarditis have been described in adults with coronavirus disease 2019 (COVID-19). Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children is typically minimally symptomatic. We report a series of febrile pediatric patients with acute heart failure potentially associated with SARS-CoV-2 infection and the multisystem inflammatory syndrome in children as defined by the US Centers for Disease Control and Prevention. Methods: Over a 2-month period, contemporary with the SARS-CoV-2 pandemic in France and Switzerland, we retrospectively collected clinical, biological, therapeutic, and early outcomes data in children who were admitted to pediatric intensive care units in 14 centers for cardiogenic shock, left ventricular dysfunction, and severe inflammatory state. Results: Thirty-five children were identified and included in the study. Median age at admission was 10 years (range, 2–16 years). Comorbidities were present in 28%, including asthma and overweight. Gastrointestinal symptoms were prominent. Left ventricular ejection fraction was &lt;30% in one-third; 80% required inotropic support with 28% treated with extracorporeal membrane oxygenation. Inflammation markers were suggestive of cytokine storm (interleukin-6 median, 135 pg/mL) and macrophage activation (D-dimer median, 5284 ng/mL). Mean BNP (B-type natriuretic peptide) was elevated (5743 pg/mL). Thirty-one of 35 patients (88%) tested positive for SARS-CoV-2 infection by polymerase chain reaction of nasopharyngeal swab or serology. All patients received intravenous immunoglobulin, with adjunctive steroid therapy used in one-third. Left ventricular function was restored in the 25 of 35 of those discharged from the intensive care unit. No patient died, and all patients treated with extracorporeal membrane oxygenation were successfully weaned. Conclusions: Children may experience an acute cardiac decompensation caused by severe inflammatory state after SARS-CoV-2 infection (multisystem inflammatory syndrome in children). Treatment with immunoglobulin appears to be associated with recovery of left ventricular systolic function.