AB1052 EVALUATION OF SYMPTOMS, DEPRESSION AND ANXIETY LEVELS IN YOUNG WOMEN WITH IDIOPATHIC GRANULOMATOUS MASTITIS
Authors: D. Yalcin Kehribar, T. Izci Duran, M. Ozgen
Journal: Annals of the Rheumatic Diseases (2020)

Background: Idiopathic granulomatous mastitis (IGM) is a rare, chronic, inflammatory disease of the breast characterized by lobulocentric granulomas, and diagnostic and therapeutic procedures are challenging for patients [1]. Glucocorticoids, immunosuppressive drugs, surgical and conservative treatment are used for the treatment of the disease [2]. These patients have many risk factors for delayed wound healing after surgical intervention, fistula formation, secondary infection and frequent postoperative recurrence for anxiety and depression [3]. Objectives: The aim of this study was to investigate the anxiety and depression levels and influential effects of clinical and sociodemographic characteristics of patients with IGM. Methods: 32 female patients enrolled to the study and who diagnosed as histopathologically proven IGM were included in this study. The sociodemographic and clinical characteristics of the patients were recorded and Beck depression inventory as well as health anxiety inventory were applied to the patients. In the same period, a control group consisting of age and sex matched people without any chronic disease was formed from health employees and their relatives. Correlation and logistic regression analyzes were performed between clinical and sociodemographic characteristics and scale scores. Results: A total of 32 patients and 32 age and sex matched volunteers were included in the study. A significant difference was found between the Beck depression inventory and health anxiety inventory scores between the patient and control groups. There was a strong correlation between breast mass size and Beck depression inventory (r: 0.83, p: 0.01), in addition moderate correlation was found between breast mass size and health anxiety (r: 0.39, p: 0.05). In the logistic regression model (χ2: 12.274, R2: 0.469, p: 0.01) created by the retrospective elimination method, presentation with fistula (OR: 9.24), bilateral lesion (OR: 7.25) and disease duration (for each month OR:1.29) were found to be significant. Conclusion: Studies show that patients with IGM experience severe anxiety and have a high risk of developing depression [4], similar in breast cancer even though the method and assessment tools are different than breast cancer. In this study, it was determined that IGM increases anxiety and depression levels in young female patients during both diagnosis and treatment. For this reason, it is thought that psychosocial evaluation of patients from the time of diagnosis, referring them to psychiatric treatment if necessary may improve the quality of life of the patients. References: [1]Kessler, E. and Y. Wolloch, Granulomatous mastitis: a lesion clinically simulating carcinoma. Am J Clin Pathol, 1972. 58(6): p. 642-6. [2]Lai, E.C., et al., The role of conservative treatment in idiopathic granulomatous mastitis. Breast J, 2005. 11(6): p. 454-6. [3]Kok, K.Y. and P.U. Telisinghe, Granulomatous mastitis: presentation, treatment and outcome in 43 patients. Surgeon, 2010. 8(4): p. 197-201. [4]Reich, M., A. Lesur, and C. Perdrizet-Chevallier, Depression, quality of life and breast cancer: a review of the literature. Breast Cancer Res Treat, 2008. 110(1): p. 9-17. Disclosure of Interests: None declared