The Doctor Will Call You Now! Telemedicine in the Midst of a Pandemic
Authors: Ashwin N. Ananthakrishnan, Siddharth Singh
Journal: Clinical Gastroenterology and Hepatology (2020)

The patient–physician relationship traditionally has been centered around face-to-face contact, be it at a house call, an outpatient visit, or during a hospitalization. This relationship, cemented by the image of a careful assessment of the patient's pulse by a physician or a thoughtful physical examination, has been immortalized in countless books and movies. Historically, although the applicability, convenience, and cost effectiveness of telemedicine has been recognized and supported by a scattering of evidence, telemedicine has not gained widespread popularity for a number of reasons.1Daniel H. Sulmasy L.S. Health et al.Policy recommendations to guide the use of telemedicine in primary care settings: an American College of Physicians position paper.Ann Intern Med. 2015; 163: 787-789Crossref PubMed Scopus (149) Google Scholar,2Tuckson R.V. Edmunds M. Hodgkins M.L. Telehealth. N Engl J Med. 2017; 377: 1585-1592Crossref PubMed Scopus (576) Google Scholar Both patients and providers have remained unconvinced that it can replace the value of a face-to-face encounter, and, importantly, reimbursement for telephone- or video-based appointments have been a fraction of in-person care, thereby limiting the adoption of this technology. However, the unprecedented challenges thrust on the health care system by the ongoing COVID-19 pandemic has brought telemedicine to the forefront on a broad scale as never before. In an attempt to minimize health care–associated transmission of the SARS-CoV2 infection and protect patients and providers, most major health care systems in the United States have shut down routine outpatient clinical care. Instead, and almost overnight, traditional face-to-face care has been widely replaced by telephone- or video-based visits. Although the initial impetus for this was to minimize disruption to patient care rather than a financial incentive, an important step legitimizing this as an acceptable and equivalent mechanism for care delivery were steps such as those announced by the Centers for Medicare and Medicaid services whereby video-based telemedicine visits would be reimbursed at parity with office-based appointments on a temporary and emergency basis. Hence, it is highly plausible that telemedicine is here to stay. There is a growing body of evidence that has examined the value added by telemedicine. This study by De Jong et al3de Jong M.J. Boonen A. van der Meulen-de Jong A.E. et al.Cost-effectiveness of telemedicine-directed specialized vs standard care for patients with inflammatory bowel diseases in a randomized trial.Clin Gastroenterol Hepatol. 2020; 18: 1744-1752Abstract Full Text Full Text PDF PubMed Scopus (51) Google Scholar is a cost-effectiveness analysis of a randomized trial that showed that the use of the myIBDcoach telemedicine portal reduced the number of outpatient gastroenterologist visits and hospitalizations in patients with inflammatory bowel diseases (IBDs) when compared with standard of care; of note, there was no difference in the rate of emergency visits, number of flares, or quality of life between the 2 groups.4de Jong M.J. van der Meulen-de Jong A.E. Romberg-Camps M.J. et al.Telemedicine for management of inflammatory bowel disease (myIBDcoach): a pragmatic, multicentre, randomised controlled trial.Lancet. 2017; 390: 959-968Abstract Full Text Full Text PDF PubMed Scopus (229) Google Scholar In this analysis, the authors estimated a cost saving of 547 Euros per patient annually, which, if extrapolated to the more than 3 million individuals with IBD in Europe, could result in substantially lower health expenditure related to IBD with telemedicine compared with traditional care. In a real-world setting, Allocca et al5Allocca M. Fiorino G. Furfaro F. et al.Maintaining the quality standards of care for inflammatory bowel disease patients during the COVID-19 pandemic.Clin Gastroenterol Hepatol. 2020; 18: 1882-1883Abstract Full Text Full Text PDF PubMed Scopus (40) Google Scholar described their experience during the COVID-19 pandemic in Milan where virtual consultations resulted in minimal disruptions to clinical care of established patients or those enrolled in clinical trials, although new patient appointments were deferred. Other randomized trials in IBD similarly have shown a telemedicine-based approach to be effective in improving disease activity,6Del Hoyo J. Nos P. Faubel R. et al.A web-based telemanagement system for improving disease activity and quality of life in patients with complex inflammatory bowel disease: pilot randomized controlled trial.J Med Internet Res. 2018; 20e11602Crossref PubMed Scopus (51) Google Scholar reducing IBD-related hospitalizations,7Cross R.K. Langenberg P. Regueiro M. et al.A randomized controlled trial of TELEmedicine for Patients with Inflammatory Bowel Disease (TELE-IBD).Am J Gastroenterol. 2019; 114: 472-482Crossref PubMed Scopus (95) Google Scholar and improving disease-related knowledge.8Abutaleb A. Buchwald A. Chudy-Onwugaje K. et al.Inflammatory bowel disease telemedicine clinical trial: impact of educational text messages on disease-specific knowledge over 1 year.Inflamm Bowel Dis. 2018; 24: 2191-2197Crossref PubMed Scopus (16) Google Scholar There are fewer rigorous studies of telehealth for other gastrointestinal diseases, and benefits have been noted in some, but not all, studies.9Helsel B.C. Williams J.E. Lawson K. et al.Telemedicine and mobile health technology are effective in the management of digestive diseases: a systematic review.Dig Dis Sci. 2018; 63: 1392-1408Crossref PubMed Scopus (46) Google Scholar In addition, in this issue of Clinical Gastroenterology and Hepatology, in a study of telehealth for pre–liver transplant evaluation, John et al10John B.V. Love E. Dahman B. et al.Use of telehealth expedites evaluation and listing of patients referred for liver transplantation.Clin Gastroenterol Hepatol. 2020; 18: 1822-1830Abstract Full Text Full Text PDF PubMed Scopus (58) Google Scholar showed that compared with standard of care, a telehealth approach had a shorter time to evaluation and shorter time to listing without increasing pretransplant mortality. Telemedicine has shown benefit in improving outcomes in patients with diabetes11Lee J.Y. Lee S.W.H. Telemedicine cost-effectiveness for diabetes management: a systematic review.Diabetes Technol Ther. 2018; 20: 492-500Crossref PubMed Scopus (113) Google Scholar and heart failure,12Koehler F. Koehler K. Deckwart O. et al.Efficacy of telemedical interventional management in patients with heart failure (TIM-HF2): a randomised, controlled, parallel-group, unmasked trial.Lancet. 2018; 392: 1047-1057Abstract Full Text Full Text PDF PubMed Scopus (431) Google Scholar although not all studies have shown benefit unequivocally. Apart from direct care delivered through telemedicine, integration of smartphone–linked sensors also similarly have shown modest benefit, at best.13Bloss C.S. Wineinger N.E. Peters M. et al.A prospective randomized trial examining health care utilization in individuals using multiple smartphone-enabled biosensors.PeerJ. 2016; 4: e1554Crossref PubMed Scopus (66) Google Scholar Although the study by de Jong et al suggested that for patients with IBD a telemedicine approach can be cost saving in the context of a clinical trial, there are many unanswered questions that remain in translating this to routine care after COVID-19. Although a brief telemedicine visit may work well for monitoring of well-controlled chronic diseases on stable therapy in an engaged patient group, whether it would offer the same degree of reassurance and empathy in a patient newly confronted with a challenging diagnosis (eg, a new diagnosis of IBD) or treatment choice (eg, initiation of long-term immunosuppressive therapy or consideration of a permanent stoma) remains to be established. Indeed, one cannot yet envision counseling a patient about a new diagnosis of advanced-stage cancer or the futility of further treatment over a telemedicine portal. The art of medicine often involves assessment of the unspoken, an exchange of a furtive glance between the child and the parent or between spouses, that suggest to the provider that one party may be underplaying their symptoms or overemphasizing their treatment adherence. How the patient carries themselves, whether they are comfortable or in distress, are important components of the overall assessment of the clinical status of the patient but cannot be inferred remotely with both parties seated at their video screens from the beginning to the end of the visit. Anecdotally, in our personal experience, telemedicine visits have been significantly shorter than face-to-face encounters with the same patient. Whether the shortening of the 15-minute in-person visit to a 5-minute video call just distills out the extraneous without meaningfully impacting patient care or whether the gap represents questions that were unasked and unanswered can be debated, but likely will include parts of both. Indeed, the meaningless chatter at the beginning and end of in-person visits may strengthen the patient–provider relationship, encouraging adherence to therapy and showing openness to engagement; and this relationship-building may end up being sacrificed at the altar of telemedicine. Although the population as a whole is more technologically savvy than a couple of decades ago, certain patient populations, including the elderly and socioeconomically or developmentally disadvantaged, may not be in a position to participate or benefit optimally from telemedicine consultations, and thus this system has the potential to unintentionally create bias. In addition, health discussions may involve sensitive topics that are challenging to conduct at the best of times within the 4 walls of an office room, let alone with the physical and technological porousness of telemedicine. Once (and hopefully sooner rather than later) the curve has been flattened on this pandemic and things are ready to move back to the regular order of business, should telemedicine be abandoned once again in favor of face-to-face office visits? To do so would be an enormous disservice. As the study in this issue of Clinical Gastroenterology and Hepatology emphasizes, telemedicine has the potential to be significantly cost saving to the health care system and, indeed, to society. In regions of the country where specialist centers are few and far between, telemedicine is critical to allow many patients to benefit from remote specialist care, ensuring they have access to the state-of-the art treatment algorithms despite the geographic distance. For the stable, well-controlled patient or a general well visit, an in-person office visit often may mean several hours away from home or work in terms of commute, waiting, and the visit itself. Telemedicine will be an attractive alternative in that setting. Indeed, the efficiency conferred by incorporating telemedicine for such situations may free up office and provider time for other patients in need. There are several opportunities to enhance a simple video or telephone appointment through the use of technology incorporating remote vital signs (such as through a smart watch) and point-of-care laboratory assessments that can be performed at home. It is important to remember that the more sophisticated the technological platform, the greater the likelihood of introducing inequality in care such that not all patients will be in a position to benefit equally from and adopt such technology. From a payor standpoint, it is important to permanently recognize the value of care delivered through telemedicine and make doing so sustainable to health care systems and providers. Without the appropriate reimbursement and recognition, widespread adoption will remain unlikely. In conclusion, an unprecedented pandemic has brought telemedicine to the forefront of medical care. It is important for us to learn from our shared experiences in this situation so that once we return to the regular order of business, we do not make the mistake of either entirely reverting back to the old or abandoning the tried and tested for the new and shiny, but instead appropriately mix the two to concoct a delicious cocktail. Use of Telehealth Expedites Evaluation and Listing of Patients Referred for Liver TransplantationClinical Gastroenterology and HepatologyVol. 18Issue 8PreviewLiver transplantation is the only treatment that increases survival times of patients with decompensated cirrhosis. Patients who live farther away from a transplant center are disadvantaged. Health care delivery via telehealth is an effective way to manage patients with decompensated cirrhosis remotely. We investigated the effects of telehealth on the liver transplant evaluation process. Full-Text PDF Maintaining the Quality Standards of Care for Inflammatory Bowel Disease Patients During the COVID-19 PandemicClinical Gastroenterology and HepatologyVol. 18Issue 8PreviewSince February 20, 2020, the SARS-COV2 infection has spread in Lombardy, and in the rest of the Italian regions, forcing our government to impose a national lockdown.1 Hospitals have been forced to adapt and to restructure their units to cope with this urgent new critical situation.2 Alternative solutions have been found to manage patients with inflammatory bowel disease (IBD), including remote monitoring, drug home delivery, limitations for infusion units, and patient education on measures to prevent infection,3 to maintain high-quality care.4 Full-Text PDF Cost-effectiveness of Telemedicine-directed Specialized vs Standard Care for Patients With Inflammatory Bowel Diseases in a Randomized TrialClinical Gastroenterology and HepatologyVol. 18Issue 8PreviewTelemedicine can be used to monitor determinants and outcomes of patients with chronic diseases, possibly increasing the quality and value of care. Telemedicine was found to reduce outpatient visits and hospital admissions for patients with inflammatory bowel diseases (IBD). We performed a full economic evaluation of telemedicine interventions in patients with IBD, comparing the cost-utility of telemedicine vs standard care. Full-Text PDF