Cross-Sex Hormones and Acute Cardiovascular Events in Transgender Persons
Authors: Michael Goodman, Darios Getahun, Michael J. Silverberg, Joshua Safer, Vin Tangpricha
Journal: Annals of Internal Medicine (2019)

Letters15 January 2019Cross-Sex Hormones and Acute Cardiovascular Events in Transgender PersonsMichael Goodman, MD, MPH, Darios Getahun, MD, PhD, Michael J. Silverberg, PhD, Joshua Safer, MD, and Vin Tangpricha, MD, PhDMichael Goodman, MD, MPHEmory University, Atlanta, Georgia (M.G., V.T.)Search for more papers by this author, Darios Getahun, MD, PhDKaiser Permanente Southern California, Pasadena, California (D.G.)Search for more papers by this author, Michael J. Silverberg, PhDKaiser Permanente Northern California, Oakland, California (M.J.S.)Search for more papers by this author, Joshua Safer, MDMount Sinai School of Medicine, New York, New York (J.S.)Search for more papers by this author, and Vin Tangpricha, MD, PhDEmory University, Atlanta, Georgia (M.G., V.T.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/L18-0564 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:Ms. Goldstein and colleagues contend that the associations reported in our study may be attributable to uncontrolled confounders, such as psychological distress, underutilization of preventive services, and differences in cardiovascular health status at baseline. These factors are worth noting but would explain away our findings only if they acted similarly for transfeminine and transmasculine participants. However, the clear positive associations are observed only in the former group. These factors also would be expected to affect risks for all 3 of the cardiovascular conditions under study (that is, ischemic stroke, venous thromboembolism, and myocardial infarction), but the risk for ... Author, Article, and Disclosure InformationAffiliations: Emory University, Atlanta, Georgia (M.G., V.T.)Kaiser Permanente Southern California, Pasadena, California (D.G.)Kaiser Permanente Northern California, Oakland, California (M.J.S.)Mount Sinai School of Medicine, New York, New York (J.S.)Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M17-2785. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoCross-sex Hormones and Acute Cardiovascular Events in Transgender Persons Darios Getahun , Rebecca Nash , W. Dana Flanders , Tisha C. Baird , Tracy A. Becerra-Culqui , Lee Cromwell , Enid Hunkeler , Timothy L. Lash , Andrea Millman , Virginia P. Quinn , Brandi Robinson , Douglas Roblin , Michael J. Silverberg , Joshua Safer , Jennifer Slovis , Vin Tangpricha , and Michael Goodman Cross-Sex Hormones and Acute Cardiovascular Events in Transgender Persons Zil Goldstein , Carl Streed , Tamar Resiman , Monica Mukherjee , and Asa Radix Metrics Cited byPharmacokinetics of Sublingual Versus Oral Estradiol in Transgender WomenCharacteristics of Transgender Women Referred to Women's Heart ClinicPreventing cardiovascular disease among sexual and gender minority personsSpecial Considerations Related to Race, Sex, Gender, and Socioeconomic Status in the Preoperative EvaluationContraception across the transmasculine spectrum 15 January 2019Volume 170, Issue 2Page: 143KeywordsDisclosureDrug administrationDrugsHormonal therapyHormonesIschemic strokeMyocardial infarctionRoutes of administrationSexual identityVenous thromboembolism ePublished: 15 January 2019 Issue Published: 15 January 2019 Copyright & PermissionsCopyright © 2019 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...