Annals On Call - SGLT2 Inhibitor–Associated Ketoacidosis—A History Lesson
Authors: Robert M. Centor, Bruce R. Leslie
Journal: Annals of Internal Medicine (2020)

Web Exclusives17 March 2020Annals On Call - SGLT2 Inhibitor–Associated Ketoacidosis—A History LessonFREERobert M. Centor, MD and Bruce R. Leslie, MD, MSPHRobert M. Centor, MDHuntsville Regional Medical Campus, University of Alabama Birmingham School of Medicine, Birmingham, Alabama (R.M.C.)Search for more papers by this author and Bruce R. Leslie, MD, MSPHSeventh Doctor Consulting, Princeton, New Jersey (B.R.L.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/A19-0026 CME/MOC SectionsAboutVisual Abstract ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail In this episode of Annals On Call, Dr. Centor discusses ketoacidosis associated with SGLT2 inhibitors with Dr. Bruce Leslie. They discuss the history of the progenitor of SGLT2 inhibitors and how recognition of this history could have provided earlier alerts to this adverse effect of SGLT2 inhibitors.Annals articles discussed include...Sodium–Glucose Cotransporter-2 Inhibitors: Lack of a Complete History Delays Diagnosis: https://annals.org/aim/fullarticle/2751428/sodium-glucose-cotransporter-2-inhibitors-lack-complete-history-delays-diagnosisAmnesia, Adverse Effects, and the Angel of History: https://annals.org/aim/fullarticle/2751434/amnesia-adverse-effects-angel-historyAbout Annals On CallAnnals On Call focuses on a clinically influential article published in Annals of Internal Medicine. Dr. Robert Centor shares his own perspective on the material and interviews topic area experts to discuss, debate, and share diverse insights about patient care and health care delivery.For more information on Annals On Call and for more episodes, visit go.annals.org/OnCall. Comments0 CommentsSign In to Submit A Comment Harvey Lee, MDACP memebr22 October 2020 More aware. I am now more aware of risk of ketoacidosis with SGLT-2 inhibitors Author, Article, and Disclosure InformationAffiliations: Huntsville Regional Medical Campus, University of Alabama Birmingham School of Medicine, Birmingham, Alabama (R.M.C.)Seventh Doctor Consulting, Princeton, New Jersey (B.R.L.)Disclosures: Dr. Centor has disclosed the following: Honoraria: Medscape. Dr. Leslie has disclosed no conflicts of interest.Editors' Disclosures: Christine Laine, MD, MPH, Editor in Chief, reports that her spouse has stock options/holdings with Targeted Diagnostics and Therapeutics. Darren B. Taichman, MD, PhD, Executive Editor, reports that he has no financial relationships or interests to disclose. Cynthia D. Mulrow, MD, MSc, Senior Deputy Editor, reports that she has no relationships or interests to disclose. Jaya K. Rao, MD, MHS, Deputy Editor, reports that she has stock holdings/options in Eli Lilly and Pfizer. Christina C. Wee, MD, MPH, Deputy Editor, reports employment with Beth Israel Deaconess Medical Center. Sankey V. Williams, MD, Deputy Editor, reports that he has no financial relationships or interests to disclose. Yu-Xiao Yang, MD, MSCE, Deputy Editor, reports that he has no financial relationships or interest to disclose. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoSodium–Glucose Cotransporter-2 Inhibitors: Lack of a Complete History Delays Diagnosis Bruce R. Leslie , Leslie E. Gerwin , and Simeon I. Taylor Amnesia, Adverse Effects, and the Angel of History Jeremy A. Greene Metrics 17 March 2020Volume 172, Issue 6Page: OC1KeywordsAmnesiaConflicts of interestDiagnostic techniquesDisclosureHealth careHistory of medicinePatients ePublished: 17 March 2020 Issue Published: 17 March 2020 Copyright & PermissionsCopyright © 2020 by American College of Physicians. All Rights Reserved.Loading ...