tbuckley/cabot-search huggingface dataset:
Evaluating Outcomes for Autologous Hematopoietic Cell Transplantation for Diffuse Large B-Cell Lymphoma in the CAR-T Era
Authors: Pranav R Santapuram, Manali Rupji, Michael Graiser, Edmund K. Waller, Kristie A. Blum, Pamela B. Allen, Jean L. Koff, Leonard Heffner, Mary Jo Lechowicz, Sagar Lonial, Jonathan L. Kaufman, Craig C Hofmeister, Madhav V. Dhodapkar, Ajay Nooka, William Blum, Rebecca B. Klisovic, Nisha Joseph, Vikas A. Gupta, Amelia Langston, Jonathon B. Cohen
Journal: Blood (2020)
Contribution of a Blood-Based Protein Biomarker Panel to the Classification of Indeterminate Pulmonary Nodules
Authors: Edwin J. Ostrin, Leonidas E. Bantis, David O. Wilson, Nikul Patel, Renwei Wang, Deepali Kundnani, Jennifer Adams-Haduch, Jennifer B. Dennison, Johannes F. Fahrmann, Hsienchang Thomas Chiu, Adi Gazdar, Ziding Feng, Jian-Min Yuan, Samir M. Hanash
Journal: Journal of Thoracic Oncology (2020)
A Multicenter, Multicohort, Open-Label, Single-Arm per Cohort, Phase II Study to Assess the Efficacy and Safety of Tabelecleucel in Patients with EBV-Associated Diseases Using an Adaptive Two-Stage Study Design
Authors: S Prockop, R Dinavahi, W Navarro, N Guzman-Becerra, Y Sun, L Gamelin
Journal: Blood (2020)
Impact of socioeconomic status in patients hospitalised for COVID-19 in the Greater Paris area
Authors: Lucile Sesé, Yann Nguyen, Etienne Giroux Leprieur, Isabella Annesi-Maesano, Catherine Cavalin, Jeanne Goupil de Bouillé, Louis Demestier, Robin Dhote, Yacine Tandjaoui-Lambiotte, Adeline Bauvois, Marion Pépin, Sonja Curac, Sébastien Beaune, Boris Duchemann, Hilario Nunes
Journal: European Respiratory Journal (2020)

<b>Individual precarity seems to be associated with the initial severity of COVID-19 in hospitalised patients under the age of 70 years. Low socioeconomic status may contribute to the excess mortality observed in the poorest district of Greater Paris.</b>https://bit.ly/3kuStXS
CD19 CAR-T Cells Treatment Conferred a Sustained Remission in Patients with Chemotherapy-Refractory MRD in B-ALL
Authors: Wenyi Lu, Yunxiong Wei, Yaqing Cao, Xia Xiao, Qing Li, Hairong Lyu, Yili Jiang, Huan Zhang, Jia Wang, Xin Li, Yanyu Jiang, Meng Juanxia, Yuan Ting, Haibo Zhu, Xiaoyuan He, Xin Jin, Rui Sun, Tao Sui, Kaiqi Liu, Mingfeng Zhao
Journal: Blood (2020)
<i>JAK2</i> Negative Erythrocytosis Associated with <i>JAK2</i> GGCC_46/1 Haplotype, <i>Calr</i> rs1049481_G, and Normal Erythropoietin Level: Is This a New Entity?
Authors: Antonella Zagaria, Francesco Tarantini, Luisa Anelli, Paola Orsini, Angela Minervini, Nicoletta Coccaro, Elisa Parciante, Crescenzio Francesco Minervini, Cosimo Cumbo, Giuseppina Tota, Luciana Impera, Maria Rosa Conserva, Immacolata Redavid, Alessandra Ricco, Immacolata Attolico, Giorgina Specchia, Pellegrino Musto, Francesco Albano
Journal: Blood (2020)
Shaping the Future of Veterans’ Health Care
Authors: Linda McCauley, Kenneth S. Ramos
Journal: New England Journal of Medicine (2020)

Interview with Dr. Linda McCauley on historical and current concerns related to the health of U.S. veterans. (13:41)Download Members of the U.S. military are at risk for a range of combat-related injuries and hazardous exposures, and some chronic health problems can arise years after service. Although there have been important advances in our ability to care for veterans, challenges remain.
Novel CoupledCARTM Technology for Treating Colorectal Cancer
Authors: Lei Xiao, Song Li, Chengfei Pu, Zhiyuan Cao, Xinyi Yang, Ning Li, Youli Luo, Haiyan Zhao, Hang Yang, Xi Huang, Xiaogang Shen, Xiuwen Wang, Yongping Song, Junjie Mao, Pengfei Pang, Qun Hu, Zhao Wu
Journal: Blood (2020)
Building Capacity and Assessing Stroke Risk with Transcranial Doppler Ultrasonography in Sub-Saharan Africa: The Reach Experience
Authors: Brigida Santos, Maria Nakafeero, Adam Lane, Leon Tshilolo, Thomas N. Williams, Peter Olupot-Olupot, Janet Adams, Banu Aygun, Susan E. Stuber, George A. Tomlinson, Teresa Latham, Patrick T. McGann, Russell E. Ware
Journal: Blood (2020)
Comparison of the Transcriptomic Signatures in Pediatric and Adult CML
Authors: Minyoung Youn, Hee-Don Chae, Stephanie M. Smith, Alex Gia Lee, Lara C. Murphy, Michele Donato, Alejandro Sweet-Cordero, Parveen Abidi, Henrique Bittencourt, Norman J. Lacayo, Gary Dahl, Catherine Aftandilian, Kara L Davis, Jairo A. Matthews, Steven M. Kornblau, Min Huang, Nathan Sumarsono, Michele Redell, Cecilia H. Fu, I-Ming L Chen, Todd A. Alonzo, Elizabeth A. Eklund, Jason Gotlib, Purvesh Khatri, Nobuko Hijiya, Kathleen M. Sakamoto
Journal: Blood (2020)
SP0017 Lessons learned from lyme disease: only persistent bacteria or autoimmunity
Authors: B Huber
Journal: Annals of the Rheumatic Diseases (2001)

<h3></h3> Antibiotic treatment-resistant Lyme arthritis is a chronic inflammatory joint disease, associated with a limited number of MHC alleles, including HLA DRb1*0401. A marked antibody and T cell response to outer surface protein A (OspA) of Borrelia burgdorferi, the causative agent of Lyme disease, is often seen during prolonged episodes of arthritis. An autoimmune mechanism has been implicated due to the lack of the Borrelia burgdorferi antigen in the target organ and apparent cross-reaction at the T cell level between the bacterial OspA and a self-protein, LFA-1aL. To directly test this hypothesis, we isolated and cloned T cells specific for the immunodominant epitope of OspA, OspA165–174, from five DRb1*0401+ patients, using OspA-class II tetramers. These clones were tested for their ability to respond to peptide containing the human homologue of OspA165–174, LFA-1aL332–340, as determined by proliferation and cytokine production. All of the T cell lines responded to minute concentrations of OspA165–174 by proliferation and secretion o IFN-g and IL-13. In contrast, larger concentrations of LFA-1aL326–345 were required for stimulation, and only 10% of the clones proliferated vigorously. With this stimulation, approximately half of the cell lines secreted IL-13 but produced no IFN-g. LFA-1aL-tetramers required a 2.5- to 25-fold higher concentration to stain dual reactive clones than OspA tetramer. Our analysis at the clonal level demonstrate that LFA-1aL326–345 behaves as an analogue for the OspA peptide, but a greater concentration of the LFA-1 peptide is required and an altered cytokine response is elicited. Thus, a single bacterial-specific T cell may respond to a cross-reactive human protein, LFA-1aL, indicating a role for molecular mimicry, and thus, autoimmunity, in treatment resistant Lyme arthritis.
Superior Therapy Response Predictions for Patients with Myelodysplastic Syndrome (MDS) Using Cellworks Singula™: Mycare-020-02
Authors: Anthony S. Stein, Drew Watson, Prashant Ramachandran Nair, Kabya Basu, Yashaswini S Ullal, Adity Ghosh, Yugandhara Narvekar, Himanshu Grover, Diwyanshu Sahu, Annapoorna Prakash, Liptimayee Behura, Veena Balakrishnan, Kunal Ghosh Roy, Swaminathan Rajagopalan, Aftab Alam, Rajan Parashar, Nirjhar Mundkur, James Christie, Michele Dundas Macpherson, Shweta Kapoor, Guido Marcucci
Journal: Blood (2020)
Abstract S10-03: Increased risk of COVID-19-related death among cancer survivors
Authors: Jie Shen, Hua Zhao
Journal: Clinical Cancer Research (2020)

Abstract Significant variations in experience of the COVID-19 pandemic have been observed in the United States. Increased risk of COVID-19-related death has been reported among cancer survivors, but due to limited sample size in those studies, to what extent the previous cancer diagnosis may play a role in the determination of COVID-19-related death is still unclear. In this study, using aggregated real-world data extracted from TriNetx electronic medical record data from 34 hospitals around United States, we assessed the relationship between prior cancer diagnosis in the past 5 years and COVID-19-related death within one month after the diagnosis of virus contraction. A total of 24,534 patients aged 18-80 years old who contracted COVID-19 were identified from January 20th to May 4th, 2020. Among them, 3,619 were cancer survivors. In the univariate analysis, we found that cancer patients had 2.55-fold increased risk ratio (RR) of death than those without cancer (RR=2.55, 95% Confidence Interval (CI): 2.25, 2.88), although the risk was decreased but still significant (RR=1.42, 95% CI: 1.21, 1.67) after adjustment for demographics (e.g., age, gender, and race) and other pre-existing chronic diseases, including obesity, diabetes, hypertension, chronic ischemic heart disease, chronic kidney disease, asthma, and COPD. When stratified by cancer sites, significant associations were observed between respiratory and intrathoracic, oral, digestive, breast, male genital, urinary, blood, and skin cancers with COVID-19-related death in the univariate analysis. As expected, the most significant cancer site was respiratory and intrathoracic cancer with an RR of 6.49 (95% CI: 5.21, 8.07). However, after adjustment for demographics and other pre-existing chronic diseases, the significant associations remained for respiratory and intrathoracic, digestive, and blood cancers (RR=1.89, 95% CI: 1.31, 2.73; RR=1.59, 95% CI: 1.06, 2.38; RR=2.08, 95% CI: 1.51, 2.86, respectively). In addition, among cancer survivors, men were found to have higher RR of death than women (RR=1.41, 95% CI: 1.12, 1.78), but the RR did not differ between Blacks and Whites. In summary, our data show significant increased COVID-19-related death among cancer survivors. The elevated risk was particularly evident among those who had respiratory and intrathoracic, digestive, and blood cancers. Citation Format: Jie Shen, Hua Zhao. Increased risk of COVID-19-related death among cancer survivors [abstract]. In: Proceedings of the AACR Virtual Meeting: COVID-19 and Cancer; 2020 Jul 20-22. Philadelphia (PA): AACR; Clin Cancer Res 2020;26(18_Suppl):Abstract nr S10-03.
Venous Thromboembolism Incidence and Impact on Survival in Patients with Brain Metastases
Authors: Vaibhav Kumar, Xi Zhou, Benjamin Shiang Wu, Joshua Herb, Tzy-Mey Kuo, Laura Green, Chris D Baggett, Bradford Jackson, Nigel S. Key, Jennifer L Lund, Katherine E Reeder-Hayes
Journal: Blood (2020)
Novel Semi-Mechanistic Model Leveraging Preclinical and Clinical Data to Inform the Recommended Phase 2 Dose (RP2D) Selection for Epcoritamab (DuoBody CD3xCD20)
Authors: Tommy Li, Ida H Hiemstra, Christopher Chiu, Roberto S Oliveri, Dena DeMarco, Theodora W. Salcedo, Frederikke Lihme Egerod, Manish Gupta
Journal: Blood (2020)
The Role of Checkpoint Inhibitors in Adults with Classical Hodgkin Lymphoma; A Systematic Review and Meta-Analysis of Phase II and III Clinical Trials
Authors: Yazan Samhouri, Muhammad Yasir Anwar, Ali Younas Khan, Urwat Til Vusqa, Iqraa Ansar, Muhammad S. Anil, Lynna Alnimer, Taha Sheikh, Muhammad Aslam Khan, Faiz Anwer, Salman Fazal, John Lister
Journal: Blood (2020)
A new ketogenic formulation improves functional outcome and reduces tissue loss following traumatic brain injury in adult mice
Authors: Orli Thau-Zuchman, Linda Svendsen, Simon C. Dyall, Ursula Paredes-Esquivel, Molly Rhodes, John V. Priestley, René G. Feichtinger, Barbara Kofler, Susanne Lotstra, J. Martin Verkuyl, Robert J. Hageman, Laus M. Broersen, Nick van Wijk, Jose P. Silva, Jordi L. Tremoleda, Adina T. Michael-Titus
Journal: Theranostics (2020)

Rationale: Traumatic brain injury (TBI) leads to neurological impairment, with no satisfactory treatments available.Classical ketogenic diets (KD), which reduce reliance on carbohydrates and provide ketones as fuel, have neuroprotective potential, but their high fat content reduces compliance, and experimental evidence suggests they protect juvenile brain against TBI, but not adult brain, which would strongly limit their applicability in TBI.Methods: We designed a new-KD with a fat to carbohydrate plus protein ratio of 2:1, containing medium chain triglycerides (MCT), docosahexaenoic acid (DHA), low glycaemic index carbohydrates, fibres and the ketogenic amino acid leucine, and evaluated its neuroprotective potential in adult TBI. Adult male C57BL6 mice were injured by controlled cortical impact (CCI) and assessed for 70 days, during which they received a control diet or the new-KD. Results:The new-KD, that markedly increased plasma Beta-hydroxybutyrate (β-HB), significantly attenuated sensorimotor deficits and corrected spatial memory deficit.The lesion size, perilesional inflammation and oxidation were markedly reduced.Oligodendrocyte loss appeared to be significantly reduced.TBI activated the mTOR pathway and the new-KD enhanced this increase and increased histone acetylation and methylation. Conclusion:The behavioural improvement and tissue protection provide proof of principle that this new formulation has therapeutic potential in adult TBI.
Cumulative Incidences and Risk Factors for Intra and Extracranial Cerebral Arteriopathy in Sickle Cell Disease Children
Authors: Francoise Bernaudin, Suzanne Verlhac, Cécile Arnaud, Annie Kamdem, Isabelle Hau, Fouad Madhi, Ralph Epaud, Camille Jung, Corinne Pondarré
Journal: Blood (2020)
Contemporary Practice Patterns of Tyrosine Kinase Inhibitor Use Among Older Patients with Chronic Myeloid Leukemia in the United States
Authors: Rory M. Shallis, Rong Wang, Jan Philipp Bewersdorf, Amer M. Zeidan, Scott F. Huntington, Amy J Davidoff, Xiaomei Ma, Nikolai A. Podoltsev
Journal: Blood (2020)
Healthcare Resource Utilization in Transplant Patients Who Are at a Higher-Risk to Develop Cytomegalovirus Infection during Their Primary Transplant-Related Hospitalization
Authors: Sanjeet S Dadwal, Dongyun Yang, Bernard Tegtmeier, Vinod A. Pullarkat, Sally Mokhtari, Joycelynne Palmer, Jana Dickter, John Zaia, David S Snyder, Deepa Nanayakkara, Amandeep Salhotra, Alfredo Puing, Ricardo Spielberger, Karamjeet S. Sandhu, Anthony S. Stein, Randy Taplitz, Eileen P. Smith, Stephen J. Forman, Monzr M. Al Malki, Ryotaro Nakamura
Journal: Blood (2020)
Abstract MP141: Role of Cryptochrome in Angiogenesis
Authors: Kazuhito Tsuzuki, Yuuki Shimizu, Zhongyue Pu, Jyunya Suzuki, Toyoaki Murohara
Journal: Circulation Research (2020)

Background: Although clock genes generate oscillations in about 10 % of all gene expressions as a 24-hour cycle in the cellular level cooperating with the central clock, little is known about the role of clock genes in angiogenesis. Objective: The aim of this study was to determine if a peripheral clock would modulate angiogenesis in a hind limb ischemia (HLI) model. Methods and Results: First, we surgically induced the HLI model in C57BL/6J (wild type; WT) mice (N=6 for each time point) and checked mRNA expressions of clock genes in a local ischemic tissue by PCR array in the setting of blood perfusion recovery. In vitro study, we next investigated those gene expressions in human umbilical vein endothelial cells (HUVECs) with or without stimulation by growth factors. Those data demonstrated that the peripheral clock genes were modulated in ECs and tissues in the presence of growth factors and tissue ischemia. Then, we examined whether inhibition of clock gene expressions had any effects on angiogenesis. For this study, we focused on Cryptochrome (Cry), which is well known as one of the core-loop forming clock genes producing circadian rhythm in mammals. Our loss-of-function study revealed that the abilities of proliferation, migration and tube formation were significantly inhibited by Cry1 and Cry2 double knockdown in HUVECs. Interestingly, although the knockdown of Cry1 and Cry2 changed the mRNA expression of Period2, it did not affect those of BMAL1 and Clock in HUVECs. Finally, we tested if Cry1 and Cry2 double hetero knockout mice of HLI models displayed worse blood perfusion recoveries with deterioration of angiogenesis. As results, compared with control WT mice, Cry1 and Cry2 double knockout mice showed the low capillary density detected by CD31-immunohistochemistry and low tissue blood perfusion demonstrated by laser Doppler perfusion imaging (LDPI) in a HLI. Conclusion: Our data indicated that Cryptochrome as a peripheral clock plays an important role in angiogenesis of the reparative tissue ischemia model.
Upfront Autologous Hematopoietic Stem-Cell Transplantation Improves Overall Survival in Comparison with Bortezomib-Based Intensification Therapy in Newly Diagnosed Multiple Myeloma: Long-Term Follow-up Analysis of the Randomized Phase 3 EMN02/HO95 Study
Authors: Michele Cavo, Francesca Gay, Meral Beksac, Meletios A Dimopoulos, Lucia Pantani, Maria Teresa Petrucci, Luca Dozza, Bronno Van Der Holt, Sonja Zweegman, Elena Zamagni, Giuseppe A. Palumbo, Francesca Patriarca, Monica Galli, Vladimir Maisnar, Markus Hansson, Angelo Belotti, Ludek Pour, Paula F Ypma, Mariella Grasso, Sandra Croockewit, Massimo Offidani, Renato Zambello, Anna Marina Liberati, Niels Frost Andersen, Annemiek Broyl, Rossella Troia, Pellegrino Musto, Heinz Ludwig, Anna Maria Morelli, Roman Hajek, Christoph Driessen, Anders Waage, Peter Gimsing, Ulf-Henrik Mellqvist, Thilo Zander, Mario Boccadoro, Pieter Sonneveld
Journal: Blood (2020)
Disentangling the Effects of HLA DRB1*15:01 and DQB1*06:02 to Establish the True HLA Risk Allele for Inhibitor Development in the Treatment of Hemophilia A
Authors: Vincent P. Diego, Bernadette W. Luu, Alexis Garza, Marco Hofmann, Marcio A. Almeida, Jerry S. Powell, Long V. Dinh, Raja Rajalingam, Juan M Peralta, Satish Kumar, Eli Fine, Joanne E. Curran, Miguel A. Escobar, Sarah Williams-Blangero, Eugene Maraskovsky, John Blangero, Tom E. Howard
Journal: Blood (2020)
Reply to Picod <i>et al.</i>: Alteration of the Renin–Angiotensin–Aldosterone System in Shock: Role of the Dipeptidyl Peptidase 3
Authors: Lakhmir S. Chawla, Rinaldo Bellomo
Journal: American Journal of Respiratory and Critical Care Medicine (2020)

generally considered to be a pure vasopressor devoid of a direct inotropic effect.Nonetheless, whether angiotensin II exerts an inotropic effect could be dependent on the type of aggression and basal cardiac function, as well as on the endogenous concentration of angiotensin II, and deserves further explorations in animal models and patients.In conclusion, this additional hypothesis gives a glimpse into the complex picture of the RAAS perturbations during shock (Figure 1), emphasizes the need for further research in this area, and expands the spectrum of potential therapeutic targets.
Second-Generation Camelid Trike Induces Improved NK Cell Mediated Targeting of AML in Pre-Clinical Models
Authors: Martin Felices, Craig E. Eckfeldt, Todd R Lenvik, Behiye Kodal, Alexander J. Lenvik, Laura Bendzick, Caitlin Ryan, Melissa A. Geller, Sarah Cooley, Daniel J. Weisdorf, Daniel A. Vallera, Jeffrey S. Miller
Journal: Blood (2017)
Sustained cellular immune dysregulation in individuals recovering from SARS-CoV-2 infection
Authors: Jacob K. Files, Sushma Boppana, Mildred D. Perez, Sanghita Sarkar, Kelsey E. Lowman, Kai Qin, Sarah Sterrett, Eric Carlin, Anju Bansal, Steffanie Sabbaj, Dustin M. Long, Olaf Kutsch, James Kobie, Paul A. Goepfert, Nathan Erdmann
Journal: Journal of Clinical Investigation (2020)

SARS-CoV-2 causes a wide spectrum of clinical manifestations and significant mortality. Studies investigating underlying immune characteristics are needed to understand disease pathogenesis and inform vaccine design. In this study, we examined immune cell subsets in hospitalized and nonhospitalized individuals. In hospitalized patients, many adaptive and innate immune cells were decreased in frequency compared with those of healthy and convalescent individuals, with the exception of an increase in B lymphocytes. Our findings show increased frequencies of T cell activation markers (CD69, OX40, HLA-DR, and CD154) in hospitalized patients, with other T cell activation/exhaustion markers (PD-L1 and TIGIT) remaining elevated in hospitalized and nonhospitalized individuals. B cells had a similar pattern of activation/exhaustion, with increased frequency of CD69 and CD95 during hospitalization followed by an increase in PD1 frequencies in nonhospitalized individuals. Interestingly, many of these changes were found to increase over time in nonhospitalized longitudinal samples, suggesting a prolonged period of immune dysregulation after SARS-CoV-2 infection. Changes in T cell activation/exhaustion in nonhospitalized patients were found to positively correlate with age. Severely infected individuals had increased expression of activation and exhaustion markers. These data suggest a prolonged period of immune dysregulation after SARS-CoV-2 infection, highlighting the need for additional studies investigating immune dysregulation in convalescent individuals.
Abstract 392: Angiotensin II TypeI Receptor-mediated Mitochondrial Fission and Suppression of Mitophagy Play Crucial Role in Vascular Senescence and Arteriosclerosis
Authors: Yoshihiro Uchikado, Yoshiyuki Ikeda, Yuichi Sasaki, Yuichi Akasaki, Mitsuru Ohishi
Journal: Circulation Research (2020)

Introduction: Metabolic stress including oxidized low density lipoprotein (ox-LDL) cause mitochondrial dysfunction and evoke vascular senescence and atherosclerosis. Mitochondria are highly dynamic organelles that undergo quality control by mitochondrial dynamics and mitophagy. This study aims to clarify whether and how mitochondrial dynamics and mitophagy are involved in the etiology of vascular senescence and arteriosclerosis. Methods: VSMC were stimulated by ox-LDL. We also conducted in vivo experiment using C57BL6 (WT), apolipoprotein E (ApoE) deficient and the double knockout of ApoE mice and Angiotensin II Type1 Receptor (AT1R). Results: Treatment of ox-LDL forced mitochondria to fission through activation of Drp1, induced mitochondrial dysfunction and oxidative stress, and developed cellular senescence. Inhibition of either Drp1, AT1R, MAPK retarded them, suggesting that mitochondrial fission plays key roles to develop premature cellular senescence and is modulated by AT1R/MAPK signal.Administration of ox-LDL decreased the number of mitophagy assessed by electron microscopy and immunohistochemistry of LAMP2 and TOMM20. AT1R signal inhibition increased mitophagy which was not affected by Atg7 knockdown, whereas it was decreased by either Rab9 or Ulk1 knockdown. Immunohistochemistry showed Rab9 dots were co-localized to TOMM20 and LAMP2, whereas LC3 dots were not, suggesting that AT1R signal induces mitophagy through Rab9-dependent alternative autophagy. The degree of vascular senescence was higher, the number of fused mitochondria and mitochondrial function were lower and mitochondrial oxidative stress was higher in ApoE KO than those in WT. DKO attenuated these adverse effect of ApoE KO. Conclusion: AT1R regulates vascular senescence and arteriosclerosis via induction of mitochondrial fission and inhibition of mitophagy.
Tumor-Tropic Liposome-Mediated Therapeutic Delivery of mRNA for T Cell Malignancies
Authors: Shoji Saito, Ikumi Nakashima, Aiko Hasegawa, Eiichi Akahoshi, Mitsuko Ishihara-Sugano, Shigeki Yagyu, Yozo Nakazawa
Journal: Blood (2020)
Pre-Planned Interim Safety Analysis of the Niveau Trial, a Randomized Phase 3 Study for Patients with Aggressive Non-Hodgkin Lymphoma in First Relapse or Progression Not Eligible for High-Dose Chemotherapy (HDT), Testing Nivolumab in Combination with Gemcitabine, Oxaliplatin (GemOx) Plus Rituximab (R) in Case of B-Cell Lymphoma
Authors: Lorenz Thurner, Viola Poeschel, Bettina Altmann, Herve Tilly, Marc Andre, Marie Maerevoet, Thomas Weber, Joerg Hoffmann, Martin Dreyling, Herve Maisonneuve, Andrea Kerkhoff, Steven Le Gouill, Stephan Stilgenbauer, Marita Ziepert, Roch Houot, Corinne Haioun, Gerhard Held
Journal: Blood (2020)
Genotype Analysis of Adolescents with Heavy Menstrual Bleeding and Low Von Willebrand Activity - Report of a Multi-Center Study
Authors: Brooke Sadler, Charles Minard, Gabe Haller, Christina Gurnett, Sarah H. O'Brien, Allison P. Wheeler, Eric S. Mullins, Mukta Sharma, Robert F. Sidonio, Shilpa Jain, Ayesha Zia, Margaret V. Ragni, Roshni Kulkarni, Jennifer Dietrich, Peter A. Kouides, Jorge Di Paola, Lakshmi Srivaths
Journal: Blood (2020)