tbuckley/cabot-search huggingface dataset:
Rectal tonsil: a rare cause of rectal bleeding
Authors: Ignacio Moratorio, M. Alejandra Arriola, Ximena Pazos, Patricia Dorfman, Marta Otero
Journal: Endoscopy (2020)

A rectal tonsil is a lymphoid follicular hyperplasia of the rectum and a rare cause of rectal bleeding. As it is a benign lesion of uncertain etiology [1] [2], treatment is reserved for symptomatic patients [2].
GENOTYPING OF HELICOBACTER PYLORI CAGA EPIYA MOTIF AS A RISK FACTOR OF GASTRIC LESIONS SEVERITY IN A MOROCCAN POPULATION
Authors: M Reda Jouimyi, G Bounder, H Boura, I Essaidi, W Badre, M Eljihad, M Kadi, A Bendahmane, H Benomar, K Zerouali, H Lebrazi, A Kettani, F Maachi
Journal: Endoscopy (2020)

Aims Helicobacter pylori (H. pylori) persistent infection lead to atrophic gastritis (AG) and intestinal metaplasia (IM) that can lead to gastric cancer (GC). The severity of the gastric lesions is related to genetic variability of H. pylori virulence factors. The cagA gene is one of the most studied virulence factors of H. pylori and its oncogenic potential is linked to its high polymorphic EPIYA motifs. The aim of this study was to evaluate the association of EPIYA motifs with the risk of AG and IM in a Moroccan population.
Indwelling double-pigtail plastic stents for treating disconnected pancreatic duct syndrome-associated peripancreatic fluid collections: long-term safety and efficacy
Authors: Paraskevas Gkolfakis, Arnaud Bourguignon, Marianna Arvanitakis, Arthur Baudewyns, Pierre Eisendrath, Daniel Blero, Arnaud Lemmers, Myriam Delhaye, Jacques Devière
Journal: Endoscopy (2020)

Long-term transmural double-pigtail stent (DPS) placement is recommended for patients with disconnected pancreatic duct syndrome (DPDS) and peripancreatic fluid collections (peri-PFCs). The long-term safety and efficacy of indwelling DPSs were evaluated.Medical files of patients treated with DPS for DPDS-associated peri-PFC and with a follow-up ≥ 48 months were reviewed. Early ( < 30 days) and late complications of DPS placement were evaluated and the primary endpoint, i. e., incidence of late complications per 100 patient-years of follow-up, was calculated. Short- and long-term success rates of endoscopic treatment and rate of peri-PFC recurrence were among secondary endpoints.From 2002 to 2014 we identified 116 patients, with mean (SD) follow-up of 80.6 (34.4) months. Among early complications (n = 20), 6 occurred peri-interventionally. Late complications (n = 17) were mainly pain due to DPS-induced ulcer or erosion (n = 10) and 14 of these were treated conservatively or by stent removal; 2 gastro-pancreatico-colo-cutaneous fistulas and 1 persisting bleed required surgical intervention. No DPS-related deaths were recorded. The incidence rate (95 %CI) of late complications was 2.18 (1.27-3.49) per 100 patient-years of follow-up. Short- and long-term success rates (with 95 %CI) of endoscopic treatment were 97.4 % (94.5 %-100 %) and 94 % (89.6 %-98.3 %), respectively. The peri-PFC recurrence rate was 28 % (20.1 %-35.9 %), and 92.3 % of these occurred within the first 2 years. Stent migration, chronic pancreatitis, and length of stent (> 6 cm) were independently associated with higher rates of peri-PFC recurrence.Long-term transmural drainage with DPS is a safe and effective treatment for DPDS-associated peri-PFCs. However, about one quarter of peri-PFCs will recur.
Serum Desmosine Is Associated with Long-Term All-Cause and Cardiovascular Mortality in Bronchiectasis
Authors: Jeffrey T.-J. Huang, Elena Kuzmanova, Alison J. Dicker, Holly R. Keir, Simon Finch, Stefano Aliberti, Thomas C. Fardon, James D. Chalmers
Journal: American Journal of Respiratory and Critical Care Medicine (2020)
IS THE DIVERTICULAR PAPILLA A FACTOR IN THE FAILURE OF CATHETERIZATION OF THE MAIN BILE DUCT IN LITHIASIS PATHOLOGY? EXPERIENCE OF A MOROCCAN DEPARTMENT
Authors: I Elkoti, S Lmrabti, K Loubaris, H Boutalaka, S Jamal, A Sair, A Bendehmane, T Adajou, O Mohamed, R Berraida, H Seddik, A Benkirane
Journal: Endoscopy (2020)

Aims The duodenal diverticula are frequent (6 to 20%), and they preferentially sit in the papillary region and are called juxta-, peri-para-papillary or valerian. The latter may be a difficulty in the catheterization of the main bile duct and are more common in cases of associated cholelithiasis.
DIRECT ENDOSCOPIC ULTRASOUND-GUIDED GASTROENTEROSTOMY WITH LUMEN-APPOSING METAL STENTS: A RETROSPECTIVE BICENTER STUDY ON TECHNICAL FEASIBILITY AND CLINICAL OUTCOME
Authors: H Fischer, M Abdelhafez, M Götzberger, R Schmid, M Dollhopf, C Schlag
Journal: Endoscopy (2020)

Aims Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) with lumen apposing metal stents (LAMS) appears to be a promising intervention in the management of gastroduodenal obstruction as a less invasive alternative to surgery. The aim of this study was to evaluate the feasibility, safety and clinical outcome of direct EUS-GE in patients of surgical high-risk or in a palliative setting.
ENDOSCOPIC ULTRASOUND IN PEDIATRIC PATIENTS WITH GASTROINTESTINAL DISORDERS IN MEXICO
Authors: R Soto-Solis, X Tengana-Delgado, LA Waller-Gonzalez, MR Pineda-De Paz
Journal: Endoscopy (2020)

Aims Evaluate the feasibility, safeness and clinical utility of EUS in the management of gastrointestinal disorders in children at a national referral center from Mexico.
A Game Plan for the Resumption of Sport and Exercise After Coronavirus Disease 2019 (COVID-19) Infection
Authors: Dermot Phelan, Jonathan H. Kim, Eugene H. Chung
Journal: JAMA Cardiology (2020)

Diana Santos-Ferreira, MD, MMed, IOC Dip Sp Phy; Rita Tomás, MD, MS, IOC Dip Sp Phy; Hélder Dores, PhD
Growth hormone and prostate cancer risk: A case-control study
Authors: Barbara Fuhrman, Thelma C. Hurd, Holger J. Schuenemann, Teresa Quattrin, Maddalena Barba, Paola Muti
Journal: Cancer Research (2004)

1098  We conducted the present analyses to assess the association of prostate cancer risk with basal levels of growth hormone (GH), in a case-control study carried out in Buffalo, NY, between 1998 and 2001(the PROMEN study). Eighty-eight men, aged 45-85, with incident, primary pathologically confirmed prostate cancer and 251 residence-matched controls were enrolled in the study. Prostate cancer cases were enrolled and their biological specimens collected prior to any therapy. To exclude latent prostate carcinomas, the present study included only patients with clinically apparent disease (stage B and higher). Prostate cancer cases and control subjects were excluded if on hormonal treatment, or affected with metabolic or endocrine diseases. Control subjects with a prostate specific antigen (PSA) value higher than 4ng/ml were excluded from the control group. Serum basal GH levels were assayed by immunometric method after a reliability study of GH determinations in 51 healthy men over a one-year period. The intraclass correlation coefficient for matched samples was 86% (p
Studies on the Renal Circulation and Renal Function in Mitral Valvular Disease
Authors: LARS WERKÖ, EDVARDAS VARNAUSKAS, JAN EK, HÔRJE BUCHT, BENGT THOMASSON, JONAS BERGSTRÖM, HARALD ELIASCH
Journal: Circulation (1954)

In a study of the nature of the renal changes in patients with mitral stenosis, lowered renal function and reduced renal circulation the effect of Apresoline, given during heart catheterization to 12 patients with mitral stenosis of varying severity, was studied. The drug was found to increase renal blood flow (and decrease arterial blood pressure), showing that the renal changes in mitral stenosis are reversible. The two effects of Apresoline were shown to be independent of each other.
PERFORMANCE MEASURES FOR EMERGENCY LOWER GASTROINTESTINAL ENDOSCOPY
Authors: D Popovic, I Lolic, T Glišić, I Ranković, V Milivojević, VM Zarić, N Jocić, O Matejic, D Tomić, D Popovic
Journal: Endoscopy (2020)

Methods A retrospective cross-sectional study, that involved patients undergoing emergency colonoscopy at the Department of Emergency Gastroenterology, Clinical Center of Serbia was performed, for a period of two years. Data were obtained on the basis of medical records. Descriptive statistics methods were used. Continuous variables were presented as mean ± standard deviation. Discontinuous variables were presented as frequencies (percentages).
ENDOSCOPIC ULTRASOUND-GUIDED BILIARY DRAINAGE USING ELECTROCAUTERY-ENHANCED LUMEN APPOSING METAL STENTS IS A SAFE AND EFFECTIVE PROCEDURE FOR DISTAL MALIGNANT BILIARY OBSTRUCTIONS
Authors: S Magrì, L Cugia, V Pollino
Journal: Endoscopy (2020)

Aims Endoscopic ultrasound-guided biliary drainage (EUS-BD) for distal malignant biliary obstruction (MBO) is the treatment of choice after unsuccessful of endoscopic retrograde colangiopancreatography (ERCP). However the use of conventional, not dedicated stents carries a high risk of biliary leakage and adverse events. Lumen apposing metal stent with a cautery-enhanced delivery system (EC-LAMS) is a novel and promising tool that allows a BD in a single step procedure. In this study we evaluated the efficacy and safety of this stent in patients with MBO.
External validation of EULAR/ACR classification criteria for idiopathic inflammatory myopathies
Authors: Queenie Luu, Jessica Day, Alix Hall, Vidya Limaye, Gabor Major
Journal: Annals of the Rheumatic Diseases (2020)

We have read with great interest the article published by Jinnin et al , which was an external validation of sensitivity and specificity of the EULAR/ACR (European League Against Rheumatism / American College of Rheumatology) classification criteria for idiopathic inflammatory myopathies with a Japanese cohort. The title and article claim that this is the first external validation study. While this may be true for a Japanese cohort, our intention is to alert the readers to the earlier published validation studies that preceded this and help highlight the complete body of evidence that should be considered.

The idiopathic inflammatory myopathies (IIMs) are a group of uncommon disorders with a potential for significant mortality and morbidity. Progress in the understanding and management of these disorders has been …
Single cell RNA sequencing reveals AML immunoediting under pressure from engineered T cell therapy
Authors: K G Paulson, T M Schmitt, D Egan, V Voillet, M C Lahman, F D Wagener, D S Hunter, P R Muhlhauser, P C Hendrie, C Yeung, N Vigneron, B Van den Eynde, J H Bielas, M Bar, R Gottardo, A G Chapuis, P D Greenberg
Journal: Cancer Research (2018)
DOWN-REGULATION OF HYPOXIA INDUCIBILE FACTOR-1 alpha (HIF-1 alpha) EXPRESSION, THROUGH mTOR PATHWAY, BY LETROZOLE (FEMARA (R)) IN ER plus ve BREAST CANCER PATIENTS: CLINICAL IMPLICATIONS
Authors: C Foroni, S B Fox, A Berruti, L Dogliotti, A Bottini, A L Harris, D Generali
Journal: Annals of Oncology (2009)
MATERIA MEDICA AND THERAPEUTICS.
Authors: Robert Hunter Semple
Journal: JAMA (1884)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
PREPARATION PROTOCOLS BEFORE CAPSULE ENDOSCOPY
Authors: AC Gomes, A Ponte, R Pinho, A Rodrigues, M Sousa, JC Silva, E Afecto, J Carvalho
Journal: Endoscopy (2020)

Aims In the current literature, some series showed similar results between a PEG solution and a clear liquid diet on the day before the CE. The aim of this study was to compare Brotz´s enteral cleansing scales between two enteric preparation protocols in patients undergoing CE.
High Prevalence of Hepatitis C Infection Among Adult Patients at Four Urban Emergency Departments — Birmingham, Oakland, Baltimore, and Boston, 2015–2017
Authors: James W. Galbraith, Erik S. Anderson, Yu-Hsiang Hsieh, Ricardo A. Franco, John P. Donnelly, Joel B. Rodgers, Elissa M. Schechter-Perkins, William W. Thompson, Noele P. Nelson, Richard E. Rothman, Douglas A.E. White
Journal: MMWR Morbidity and Mortality Weekly Report (2020)

Identifying persons with hepatitis C virus (HCV) infection has become an urgent public health challenge because of increasing HCV-related morbidity and mortality, low rates of awareness among infected persons, and the advent of curative therapies (1). Since 2012, CDC has recommended testing of all persons born during 1945-1965 (baby boomers) for identification of chronic HCV infection (1); urban emergency departments (EDs) are well positioned venues for detecting HCV infection among these persons. The United States has witnessed an unprecedented opioid overdose epidemic since 2013 that derives primarily from commonly injected illicit opioids (e.g., heroin and fentanyl) (2). This injection drug use behavior has led to an increase in HCV infections among persons who inject drugs and heightened concern about increases in human immunodeficiency virus (HIV) and HCV infection within communities disproportionately affected by the opioid crisis (3,4). However, targeted strategies for identifying HCV infection among persons who inject drugs is challenging (5,6). During 2015-2016, EDs at the University of Alabama at Birmingham; Highland Hospital, Oakland, California; Johns Hopkins Hospital, Baltimore, Maryland; and Boston University Medical Center, Massachusetts, adopted opt-out (i.e., patients can implicitly accept or explicitly decline testing), universal hepatitis C screening for all adult patients. ED staff members offered HCV antibody (anti-HCV) screening to patients who were unaware of their status.* During similar observation periods at each site, ED staff members tested 14,252 patients and identified an overall 9.2% prevalence of positive results for anti-HCV among the adult patient population. Among the 1945-1965 birth cohort, prevalence of positive results for anti-HCV (13.9%) was significantly higher among non-Hispanic blacks (blacks) (16.0%) than among non-Hispanic whites (whites) (12.2%) (p<0.001). Among persons born after 1965, overall prevalence of positive results for anti-HCV was 6.7% and was significantly higher among whites (15.3%) than among blacks (3.2%) (p<0.001). These findings highlight age-associated differences in racial/ethnic prevalences and the potential for ED venues and opt-out, universal testing strategies to improve HCV infection awareness and surveillance for hard-to-reach populations. This opt-out, universal testing approach is supported by new recommendations for hepatitis C screening at least once in a lifetime for all adults aged ≥18 years, except in settings where the prevalence of positive results for HCV infection is <0.1% (7).
RECTAL INVOLVEMENT IN CROHN’S DESIASE PATIENTS WITH ANOPERINEAL MANIFESTATIONS
Authors: H Koulali, F Errabie, A Elmekkaoui, W Khannoussi, Z Ismaili, G Kharrasse
Journal: Endoscopy (2020)

Aims The aim of this study was to evaluate the macroscopic rectal involvement in patients with anoperineal manifestations.
RANDOMIZED CONTROLLED TRIAL COMPARING THE BOWEL CLEANSING EFFICACY OF NOVEL 1 LITRE POLYETHYLENE GLYCOL+ASCORBATE NER1006 VERSUS HIGH-VOLUME POLYETHYLENE GLYCOL USING A SPLIT DOSING REGIMEN
Authors: A Repici, C Spada, R Cannizzaro, MD Leo, M Traina, A Buda, P Occhipinti, M Manno, L Fuccio, R Maselli, PA Galtieri, P Cesaro, M Spadaccini, L Lamonaca, L Minelli, A Granata, G Antonelli, S Maiero, G Guarnieri, M Amata, M Badalamenti, A Capogreco, R Lorenzetti, A Zullo, G Pellegatta, A Fugazza, S Carrara, C Hassan
Journal: Endoscopy (2020)

Aims Efficacy and acceptability of bowel preparations are relevant for accuracy and patient-experience of colonoscopy. A novel1L-PEG+Ascorbate(PEG+A)solution has been successfully validated against low-volume regimens only. This multicenter-randomized-trial compared the efficacy, acceptability,tolerability,and safety of the 1L-PEG-A ner1006 versus a high-volume PEGregimen, both as split-dose regimens (NCT03742232).
Variation in False-Negative Rate of Reverse Transcriptase Polymerase Chain Reaction–Based SARS-CoV-2 Tests by Time Since Exposure
Authors: Lauren M. Kucirka, Stephen A. Lauer, Oliver Laeyendecker, Denali Boon, Justin Lessler
Journal: Annals of Internal Medicine (2020)

Tests for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) based on reverse transcriptase polymerase chain reaction (RT-PCR) are being used to rule out infection among high-risk persons, such as exposed inpatients and health care workers. It is critical to understand how the predictive value of the test varies with time from exposure and symptom onset to avoid being falsely reassured by negative test results.
Cells deficient in the base excision repair protein, DNA polymerase beta, are hypersensitive to oxaliplatin chemotherapy: A scientific rationale for chemo-radiation treatment
Authors: N Nicolay, J Yang, J Parsons, S Caporali, S D'Atri, C Harrington, R Singh, P Farmer, P Johnson, M Middleton, W G McKenna, G Dianov, R Sharma
Journal: Cancer Research (2009)
MOTORIZED SPIRAL ENTEROSCOPY: A SINGLE-CENTER EXPERIENCE
Authors: A Sportes, N Hanna, A Mahamat, JF Rey
Journal: Endoscopy (2020)

Aims Motorized spiral enteroscopy (PowerSpiral Olympus) is a novel technique for small bowel exploration. The aim of this study is to describe this new technique and demonstrate its advantages in terms of facility and depth in insertion, short procedure time and stability at withdrawal in patients with obscure gastrointestinal bleeding and suspected small bowel lesions on capsule endoscopy. It’s a new tool modified from the manual spiral technique.
Canakinumab for Treatment of Adult-Onset Still’s Disease to Achieve Reduction of Arthritic Manifestation (CONSIDER): phase II, randomised, double-blind, placebo-controlled, multicentre, investigator-initiated trial
Authors: Claudia Kedor, Joachim Listing, Jan Zernicke, Anja Weiß, Frank Behrens, Norbert Blank, Joerg Christoph Henes, Joern Kekow, Andrea Rubbert-Roth, Hendrik Schulze-Koops, Eva Seipelt, Christof Specker, Eugen Feist
Journal: Annals of the Rheumatic Diseases (2020)

Inhibition of interleukin (IL)-1 represents a promising treatment option in adult-onset Still's disease (AOSD).
Allogeneic Bone Marrow Transplantation, Zidovudine, and Human Immunodeficiency Virus Type 1 (HIV-I) Infection
Authors: H. Kent Holland, Rein Saral, John J. Rossi, Albert D. Donnenberg, William H. Burns, William E. Beschorner, Homayoon Farzadegan, Richard J. Jones, Gerry V. Quinnan, Georgia B. Vogelsang, Huibert M. Vriesendorp, John R. Wingard, John A. Zaia, George W. Santos
Journal: Annals of Internal Medicine (2020)

Abstract Human immunodeficiency virus type 1 (HIV-1)-infected patients with non-Hodgkin lymphoma are classified as having the acquired immunodeficiency syndrome (AIDS). Allogeneic bone marrow trans...
It felt like I was living in a fog
Authors: Elizabeth Lerner Papautsky
Journal: BMJ (2020)

It felt like I was living in a fogElizabeth Lerner Papautsky shares the impact that "chemo brain" had on her life and how this unexpected side effect of chemotherapy was the most challenging for her to manage Elizabeth Lerner Papautsky patient and human factors psychologistAfter I started chemotherapy, I spent several days feeling like a zombie.As I received more treatments, I was in an ever present haze.Sometimes I couldn't concentrate enough to read or watch television, let alone work.I became over-stimulated in noisy and crowded places.I had difficulty carrying on a conversation with several people at the same time.I tried to manage by doing the more complex tasks in the morning, then focusing on simpler tasks in the afternoon.I also started to avoid public places, including not taking my children to activities and birthday parties.I might have been more prepared for making these sacrifices had I known about "chemo brain" before starting chemotherapy.
Gastrointestinal Eosinophil Responses in a Longitudinal, Randomized Trial of Peanut Oral Immunotherapy
Authors: Benjamin L. Wright, Nielsen Q. Fernandez-Becker, Neeraja Kambham, Natasha Purington, Shu Cao, Dana Tupa, Wenming Zhang, Sayantani B. Sindher, Matthew A. Rank, Hirohito Kita, David A. Katzka, Kelly P. Shim, Bryan J. Bunning, Alfred D. Doyle, Elizabeth A. Jacobsen, Mindy Tsai, Scott D. Boyd, Monali Manohar, R. Sharon Chinthrajah
Journal: Clinical Gastroenterology and Hepatology (2020)
Voluntary collective isolation as a best response to COVID-19 for indigenous populations? A case study and protocol from the Bolivian Amazon
Authors: Hillard S Kaplan, Benjamin C Trumble, Jonathan Stieglitz, Roberta Mendez Mamany, Maguin Gutierrez Cayuba, Leonardina Maito Moye, Sarah Alami, Thomas Kraft, Raul Quispe Gutierrez, Juan Copajira Adrian, Randall C Thompson, Gregory S Thomas, David E Michalik, Daniel Eid Rodriguez, Michael D Gurven
Journal: The Lancet (2020)
ENDOSCOPIC AND HISTOLOGICAL CHARACTERISTICS OF NEW GASTRIC FINDINGS THAT APPEARED WITH STRONG ACID SECRETION SUPPRESSOR (P-CAB)
Authors: Y Kinoshita, T Yamasaki, Y Akita, K Sumiyama, M Saruta
Journal: Endoscopy (2020)

Aims There are several known gastric findings associated with the use of conventional proton pump inhibitors (PPIs). However, there are no reports of gastric findings associated with the use of potassium competitive acid blocker (P-CAB) a more potent gastric acid secretion suppressor. This time we found a new gastric finding associated with the use of P-CAB. This gastric finding is white granular findings with slight elevation similar the White Glove Appearance (WGA) which is known as a gastric finding characteristic of gastric cancer cases. Since we named this finding White Granule with Small Elevation (WGSE), we introduce the characteristics of this finding with endoscopic and histological analysis.