tbuckley/cabot-search huggingface dataset:
OP0143 PREDICTORS OF SEVERE CRANIAL ISCHEMIC COMPLICATIONS IN GIANT CELL ARTERITIS
Authors: Alojzija Hocevar, Rok Jese, Ziga Rotar, Matija Tomsic
Journal: Annals of the Rheumatic Diseases (2019)

<h3>Background</h3> Vision disturbances and ischemic stroke represent severe ischemic complications of giant cell arteritis (GCA). Despite the fast track GCA pathway since 2011 at our secondary/tertiary rheumatology center, about 10% of patients still develop permanent vision loss (PVL) or stroke. <h3>Objectives</h3> We aimed to determine markers predicting severe cranial ischemic complications in GCA. <h3>Methods</h3> We analyzed medical records of prospectively collected GCA patients diagnosed between 01.09.2011 and 31.12.2018 and compared clinical and laboratory characteristics of patients with and without vision disturbances (diplopia, transient vision loss (TVL), PVL) or ischemic stroke. <h3>Results</h3> During the 88-month observation period, we identified 250 new GCA patients (63.2% female, median (IQR) age 74.9 (67.8-79.9) years, 83.3% histologically proven, 79.8% with positive temporal artery ultrasound, 30.3% with extracranial large vessel involvement). Fifty (20.0%) patients developed either vision disturbances (16 diplopia, 10 TVL or 19 PVL) or ischemic stroke (8); isolated vision disturbances in 42, and isolated stroke in 5 patients. Conventional cardiovascular risk factors (obesity, arterial hypertension, hyperlipidemia, diabetes mellitus, and smoking were not associated with severe cranial ischemic complications (Table 1). The patients with severe cranial ischemic complications had more frequently had atrial fibrillation (RR 2.4 (95%CI 1.3-4.4), p=0.011). Twenty-five from 35 patients with atrial fibrillation were already treated with anticoagulants (10/13 in the group with cranial ischemic complication and 15/22 without them). Besides, GCA cases with severe cranial ischemic complications were significantly older (p=0.006) and more commonly reported jaw claudication (RR 1.8 (95%CI 1.4-2.3), p &lt;0.001). We found no significant differences in the median level of C-reactive protein between the compared groups, whereas the erythrocyte sedimentation rate was slightly lower (p=0.032) and haemoglobin concentration higher (p=0.030) in cases with severe cranial ischemic complications. <h3>Conclusion</h3> Increasing age and jaw claudication predicted severe cranial ischemic complications in our GCA cohort. Atrial fibrillation might represent an additional risk factor. <h3> Disclosure of Interests</h3> None declared
Incidence of severe COVID-19 outcomes in psoriatic patients treated with systemic therapies during the pandemic: A Biobadaderm cohort analysis
Authors: Ofelia Baniandrés-Rodríguez, Jaime Vilar-Alejo, Raquel Rivera, José Manuel Carrascosa, Esteban Daudén, Enrique Herrera-Acosta, Antonio Sahuquillo-Torralba, Fran J. Gómez-García, Lula María Nieto-Benito, Pablo de la Cueva, José Luis López-Estebaranz, Isabel Belinchón, Marta Ferrán Farrés, Mercè Alsina, Lourdes Rodríguez Fernández-Freire, Gregorio Carretero, Carmen García-Donoso, Ferrán Ballescá, Mar Llamas-Velasco, Enrique Herrera-Ceballos, Rafael Botella-Estrada, Diana Patricia Ruiz-Genao, Josep Riera-Monroig, Miguel Ángel Descalzo Gallego, Ignacio García-Doval, Esteban Daudén, Mar Llamas-Velasco, Cristina Santamaría, Gregorio Carretero, Jaime Vilar-Alejo, Blanca Madrid Álvarez, Raquel Rivera, Carmen García-Donoso, Ma del Mar Onteniente Gomis, Diana Batista Cabrera, Carlos Ferrándiz, José Manuel Carrascosa, Ferrán Ballescá, Pablo de la Cueva, Patricia Molina Mejías, Isabel Belinchón, Carlos García Giner, Alfred Perez, Fran J. Gómez-García, Enrique Herrera-Ceballos, Enrique Herrera-Acosta, Eliseo Martínez-García, Cristina Sánchez, José Luis López-Estebaranz, Diana Patricia Ruiz-Genao, Elena García Zamora, Marta Ferrán Farrés, Mercè Alsina, Josep Riera, Sara Pedregosa Fauste, Ofelia Baniandrés, Lula María Nieto Benito, Desiree Molina, José Luis Sánchez-Carazo, Antonio Sahuquillo-Torralba, Rafael Botella-Estrada, Conrad Pujol Marco, Natalia Chaparro Aguilera, Verónica Massó López, Lourdes Rodríguez Fernández-Freire, Almudena Mateu Puchades, Sergio Santos, Marina Sáez Belló, Ángeles Flórez Menéndez, Laura Salgado, Beatriz González Sixto, Ma Teresa Abalde, Lucia Vilanova, Alexandra Perez Mariño, Noemí Eiris, Vicenta Prieto Marcos, Ignacio García-Doval, Miguel Ángel Descalzo Gallego, Marina de Vega Martínez
Journal: Journal of the American Academy of Dermatology (2020)
PLAGL2 promotes the proliferation and migration of gastric cancer cells via USP37-mediated deubiquitination of Snail1
Authors: Liang Wu, Ning Zhao, Zili Zhou, Jinhuang Chen, Shengbo Han, Xudan Zhang, Haijun Bao, Wenzheng Yuan, Xiaogang Shu
Journal: Theranostics (2020)

Rationale: PLAGL2 (pleomorphic adenoma gene like-2), a zinc finger PLAG transcription factor, is aberrantly expressed in several malignant tumors. However, the biological roles of PLAGL2 and its underlying mechanism in gastric cancer (GC) remain unclear. Methods: A series of experiments in vitro and in vivo were conducted to reveal the role of PLAGL2 in GC progression. Results: The data revealed that PLAGL2 promotes GC cell proliferation, migration, invasion, and EMT in vitro and in vivo. Mechanistically, we demonstrated the critical role of PLAGL2 in the stabilization of snail family transcriptional repressor 1 (Snail1) and promoting Snail1-mediated proliferation and migration of GC cells. PLAGL2 activated the transcription of deubiquitinase USP37, which then interacted with and deubiquitinated Snail1 protein directly. In addition, GSK-3β-dependent phosphorylation of Snail1 protein is essential for USP37-mediated Snail1 deubiquitination regulation. Conclusions: In general, PLAGL2 promotes the proliferation and migration of GC cells through USP37-mediated deubiquitination of Snail1 protein. This work provided potential therapeutic targets for GC treatment.
Abstract 506: Enhanced Mitochondrial Calcium Uptake During Chronic β-adrenergic Stimulation Causes Maladaptive Remodeling and Impaired Left Ventricular Function Independent of Cyclophilin D-mediated Mitochondrial Permeability Transition
Authors: Joanne F Garbincius, Timothy S Luongo, Jonathan P Lambert, Adam S Mangold, Emma K Murray, Alycia N Hildebrand, Pooja Jadiya, John W Elrod
Journal: Circulation Research (2020)

The mitochondrial calcium uniporter (MCU) forms the pore of the mitochondrial calcium uniporter channel (mtCU) and is required for rapid mitochondrial Ca 2+ ( m Ca 2+ ) uptake. MCU is necessary to increase cardiac energetics to fuel an increase in cardiac contractility during acute sympathetic stimulation. However, little is known about how MCU-dependent Ca 2+ flux may contribute to the heart’s adaptations to chronic stress. We therefore compared mice with adult cardiomyocyte (ACM)-specific loss ( Mcu fl/fl ; Mcu-cKO) or gain (CAG-CAT-MCU; MCU-Tg) of MCU function to examine the role of MCU-dependent m Ca 2+ uptake in a model of chronic catecholamine overload. In vitro characterization of ACMs confirmed that MCU overexpression enhanced and Mcu deletion inhibited acute m Ca 2+ uptake. Neither loss nor gain of MCU function altered baseline contractile function in vivo . In αMHC-MCM control mice, fractional shortening was transiently increased after 2 days of isoproterenol infusion. This initial increase in contractility was attenuated in MCU-cKO mice. In contrast, MCU-Tg mice exhibited decreased fractional shortening at 7 and 14 days of isoproterenol infusion. This detrimental effect on contractile function was associated with increased LV dilation, HW/BW ratio, and lung edema. MCU-Tg cardiomyocytes in vitro exhibited increased ROS production and a trend towards increased cell death upon elevation of cytosolic Ca 2+ with ionomycin. These data prompted us to test the hypothesis that isoproterenol-induced contractile dysfunction in MCU-Tg hearts is caused by cardiomyocyte dropout due to m Ca 2+ overload and mitochondrial permeability transition. However, genetic deletion of the mPTP component cyclophilin D did not prevent the decline in contractile function, diminish cardiomyocyte death, or attenuate LV remodeling in MCU-Tg animals during chronic isoproterenol infusion. We conclude that although mtCU-dependent m Ca 2+ uptake is essential for early energetic adaptations to high adrenergic load, under conditions of chronic adrenergic stress it is maladaptive and predisposes to heart failure. Our data suggest that this maladaptive response occurs via mechanisms independent of cyclophilin D-mediated permeability transition.
Evolution of Gilteritinib Resistance from Residual Disease to Relapse
Authors: Sunil K Joshi, Tamilla Nechiporuk, Daniel Bottomly, Paul Piehowski, Julie Reisz, Janét Pittsenbarger, Sara J Gosline, Andy Kaempf, Yi-Ting Wang, Jamie Moon, Özgün Babur, Kevin M Watanabe-Smith, Emek Demir, Liu Tao, Cristina E. Tognon, Angelo D'Alessandro, Jeffrey W. Tyner, Shannon K. McWeeney, Karin Rodland, Brian J. Druker, Elie Traer
Journal: Blood (2020)
Assessment of Cellworks Omics Biosimulation Therapy Response Predictions for Patients with Acute Myeloid Leukemia (AML) Using Cellworks Singula™: Mycare-020-01
Authors: Guido Marcucci, Drew Watson, Prashant Ramachandran Nair, Kabya Basu, Yashaswini S Ullal, Adity Ghosh, Yugandhara Narvekar, Himanshu Grover, Diwyanshu Sahu, Anish Raju R Amara, Anusha Pampana, Kunal Ghosh Roy, Swaminathan Rajagopalan, Aftab Alam, Rajan Parashar, Nirjhar Mundkur, James Christie, Michele Dundas Macpherson, Shweta Kapoor, Anthony S. Stein
Journal: Blood (2020)
Partisan differences in physical distancing are linked to health outcomes during the COVID-19 pandemic
Authors: Anton Gollwitzer, Cameron Martel, William J. Brady, Philip Pärnamets, Isaac G. Freedman, Eric D. Knowles, Jay J. Van Bavel
Journal: Nature Human Behaviour (2020)

Numerous polls suggest that COVID-19 is a profoundly partisan issue in the United States. Using the geotracking data of 15 million smartphones per day, we found that US counties that voted for Donald Trump (Republican) over Hillary Clinton (Democrat) in the 2016 presidential election exhibited 14% less physical distancing between March and May 2020. Partisanship was more strongly associated with physical distancing than numerous other factors, including counties' COVID-19 cases, population density, median income, and racial and age demographics. Contrary to our predictions, the observed partisan gap strengthened over time and remained when stay-at-home orders were active. Additionally, county-level consumption of conservative media (Fox News) was related to reduced physical distancing. Finally, the observed partisan differences in distancing were associated with subsequently higher COVID-19 infection and fatality growth rates in pro-Trump counties. Taken together, these data suggest that US citizens' responses to COVID-19 are subject to a deep—and consequential—partisan divide. Gollwitzer et al. use smartphone mobility tracking to show that US county support for Trump in 2016 was associated with a lower reduction in mobility in March–May 2020, which in turn was associated with higher COVID-19 infection and fatality growth rates in pro-Trump counties.
Results of a Phase II Study of PD-1 Inhibition in Advanced Myeloproliferative Neoplasms
Authors: Gabriela S. Hobbs, Cansu Cimen Bozkus, Martha Wadleigh, Lonette Sandy, Mikaela Doughtery, Kathryn Johnson, Gillian Sanchez, Julia E. Foster, Molly Macrae, Tina T. Som, Michal Bar-Natan, Richard M. Stone, Erin Moshier, Camelia Iancu-Rubin, John Mascarenhas
Journal: Blood (2020)
Abstract 15560: Necrotizing Enterocolitis in Infants With Single Ventricle Congenital Heart Disease and a Systemic-Pulmonary Artery Shunt as the Sole Source of Pulmonary Blood Flow
Authors: Arene Butto, Sanghee Suh, Daniel Vari, Stephan Wu, Hannah Katcoff, David J Goldberg, Chitra Ravishankar, James W Gaynor, Jodi Chen, Andrew C Glatz
Journal: Circulation (2017)

Introduction: Systemic-pulmonary artery shunts (BTS) provide a stable source of pulmonary blood flow (PBF) in infants with some forms of single ventricle congenital heart disease (SVCD). These infa...
Phase Ib Study of Ianalumab (VAY736) and Ibrutinib in Patients with Chronic Lymphocytic Leukemia (CLL) on Ibrutinib Therapy
Authors: Kerry A. Rogers, Ian W. Flinn, Carolyn McGarry, Liangke Connie Gou, Nadia Hassounah, Janghee Woo, John C. Byrd
Journal: Blood (2020)
Clinicopathology, Disease Progression/Transformation and Genomic Alterations of Indolent T-Cell Lymphoproliferative Disorder of the Gastrointestinal Tract
Authors: Limin Gao, Weiping Liu, Wenyan Zhang, Sha Zhao, Yueqiang Song, Jinwei Hu, Kai Wang, Haiyan Wu
Journal: Blood (2020)
Persistent Overall Response on Early PET/CT Scans during Salvage Therapy for Relapsed or Refractory DLBCL Predicts for Disease Specific Survival
Authors: Hua-Jay J Cherng, Raphael E Steiner, Luis Fayad, Paolo Strati, Ranjit Nair, F. B. B. Hagemeister, Loretta J. Nastoupil, Hun Ju Lee, Sattva S. Neelapu, Christopher Flowers, Felipe Samaniego, Maria Alma Rodriguez, Lei Feng, Hubert Chuang, Jason R. Westin
Journal: Blood (2020)
Allogeneic Hematopoietic Cell Transplantation with Myeloablative Conditioning Regimen of Reduced Toxicity Is Associated with Favorable Survival in Patients with Secondary Acute Myeloid Leukemia
Authors: Eleni Gavriilaki, Chrysavgi Lalayanni, Ioanna Sakellari, Christos Varelas, Despina Mallouri, Ioannis Batsis, Anna Vardi, Sofia Tagara, Marianna Masmanidou, Maria Papathanasiou, Lila Papalexandri, Chrysanthi Vadikoliou, Anastasia Athanasiadou, Achilles Anagnostopoulos
Journal: Blood (2020)
Titin-truncating mutations associated with dilated cardiomyopathy alter length-dependent activation and its modulation via phosphorylation
Authors: Petr G Vikhorev, Natalia N Vikhoreva, WaiChun Yeung, Amy Li, Sean Lal, Cristobal G dos Remedios, Cheavar A Blair, Maya Guglin, Kenneth S Campbell, Magdi H Yacoub, Pieter de Tombe, Steven B Marston
Journal: Cardiovascular Research (2020)

Abstract Aims Dilated cardiomyopathy (DCM) is associated with mutations in many genes encoding sarcomere proteins. Truncating mutations in the titin gene TTN are the most frequent. Proteomic and functional characterizations are required to elucidate the origin of the disease and the pathogenic mechanisms of TTN-truncating variants. Methods and results We isolated myofibrils from DCM hearts carrying truncating TTN mutations and measured the Ca2+ sensitivity of force and its length dependence. Simultaneous measurement of force and adenosine triphosphate (ATP) consumption in skinned cardiomyocytes was also performed. Phosphorylation levels of troponin I (TnI) and myosin binding protein-C (MyBP-C) were manipulated using protein kinase A and λ phosphatase. mRNA sequencing was employed to overview gene expression profiles. We found that Ca2+ sensitivity of myofibrils carrying TTN mutations was significantly higher than in myofibrils from donor hearts. The length dependence of the Ca2+ sensitivity was absent in DCM myofibrils with TTN-truncating variants. No significant difference was found in the expression level of TTN mRNA between the DCM and donor groups. TTN exon usage and splicing were also similar. However, we identified down-regulation of genes encoding Z-disk proteins, while the atrial-specific regulatory myosin light chain gene, MYL7, was up-regulated in DCM patients with TTN-truncating variants. Conclusion Titin-truncating mutations lead to decreased length-dependent activation and increased elasticity of myofibrils. Phosphorylation levels of TnI and MyBP-C seen in the left ventricles are essential for the length-dependent changes in Ca2+ sensitivity in healthy donors, but they are reduced in DCM patients with TTN-truncating variants. A decrease in expression of Z-disk proteins may explain the observed decrease in myofibril passive stiffness and length-dependent activation.
Mild versus conventional ovarian stimulation for IVF in poor, normal and hyper-responders: a systematic review and meta-analysis
Authors: Adrija Kumar Datta, Abha Maheshwari, Nirmal Felix, Stuart Campbell, Geeta Nargund
Journal: Human Reproduction Update (2020)

Mild ovarian stimulation has emerged as an alternative to conventional IVF with the advantages of being more patient-friendly and less expensive. Inadequate data on pregnancy outcomes and concerns about the cycle cancellation rate (CCR) have prevented mild, or low-dose, IVF from gaining wide acceptance.
Prognosis Impact of Positive Minimal Residual Disease By Flow Cytometry Prior to Transplant According to the Cut-Off Threshold in Patients with Acute Myeloid Leukemia
Authors: Claudia Nunez-Torron, Fernando Martin Moro, Juan Marquet Palomanes, Miguel Piris-Villaespesa, Ernesto Roldan, Alejandro Luna, Adolfo Saez, Valentín Garcia-Gutiérrez, Lucía Rubio, Maria Eulalia Rodriguez, Anabelle Chinea, Ana Lario, Gemma Moreno Jiménez, Javier Lopez Jimenez, Pilar Herrera Puente
Journal: Blood (2020)
Long-Term Cardiac, Vascular, and Hypertension Safety of Bosutinib (BOS) Versus Imatinib (IMA) for Newly Diagnosed Chronic Myeloid Leukemia (CML): Results from the Bfore Trial
Authors: Jorge E. Cortes, Philipp D le Coutre, Carlo Gambacorti-Passerini, Henrik Hjorth-Hansen, Pia Raanani, Valentín Garcia-Gutiérrez, Vamsi Kota, Simon Purcell, Andrea Viqueira, Eric Leip, Tim H Brümmendorf
Journal: Blood (2020)
Characteristics and Treatment Response of Newly Diagnosed Advanced-Stage and Relapsed/Refractory Hodgkin Lymphoma in Taiwan: A Nationwide Retrospective Study
Authors: Chieh-Lin Jerry Teng, Tran-Der Tan, Yu-Wen Lin, Pei-Wen Lien, Hsin-Chun Chou, Fang-Ju Lin
Journal: Blood (2020)
Nivolumab Combined with Brentuximab Vedotin for Relapsed/Refractory Mediastinal Gray Zone Lymphoma: Primary Efficacy and Safety Analysis of the Phase 2 CheckMate 436 Study
Authors: Armando Santoro, Alison J. Moskowitz, Silvia Ferrari, Carmelo Carlo-Stella, Michelle A. Fanale, Stephen Francis, Mariana Sacchi, Kerry J. Savage
Journal: Blood (2020)
To Treat or Not to Treat—Balancing Benefits and Risks of Treatment Delay Among Patients With Cancer During the COVID-19 Pandemic
Authors: Elizabeth Garrett-Mayer, Brian I. Rini
Journal: JAMA Oncology (2020)

Holly E. Hartman, MS; Yilun Sun, PhD; Theresa P. Devasia, MS; Elizabeth C. Chase, MS; Neil K. Jairath, BS; Robert T. Dess, MD; William C. Jackson, MD; Emily Morris, MS; Pin Li, PhD; Kimberly A. Hochstedler, MS; Madeline R. Abbott, MS; Kelley M. Kidwell, PhD; Vonn Walter, PhD; Ming Wang, PhD; Xi Wang, MS; Nicholas G. Zaorsky, MD; Matthew J. Schipper, PhD; Daniel E. Spratt, MD
A Phase 1/1b Safety Study of Prgn-3006 Ultracar-T™ in Patients with Relapsed or Refractory CD33-Positive Acute Myeloid Leukemia and Higher Risk Myelodysplastic Syndrome
Authors: David A. Sallman, Hany Elmariah, Kendra L. Sweet, Chetasi Talati, Asmita Mishra, Linda L. Kelley, Amy Lankford, Tim Chan, Rutul R Shah, Eric Padron, Rami S. Komrokji, Jeffrey E. Lancet, Helen Sabzevari, Marco L. Davila, Nelli Bejanyan
Journal: Blood (2020)
GBT021601 Inhibits HbS Polymerization, Prevents RBC Sickling and Improves the Pathophysiology of Sickle Cell Disease in a Murine Model
Authors: Kobina Dufu, Carsten Alt, Steven Strutt, Tzechiang Tang, Hilary Liao-Zou, Yue Yuan, Brian E Cathers, Donna Oksenberg
Journal: Blood (2020)
Outcome of Immune Thrombocytopenia in Pregnancy: A French Nationwide Prospective Multicenter Observational Case-Control Study
Authors: Stephanie Guillet, Valentine Loustau, Anissa Zarour, Emmanuelle Boutin, Thibault Comont, Nathalie Costedoat-Chalumeau, Brigitte Pan-Petesch, Delphine Gobert, Stephane Cheze, Odile Souchaud-Debouverie, Jean-Francois Viallard, Anne-Sophie Morin, Gaetan Sauvetre, Manuel Cliquennois, Bruno Royer, Corinne Haioun, Agathe Masseau, Louis Terriou, Claire Fieschi, Matthieu Mahevas, Marc Michel, Bertrand Godeau
Journal: Blood (2020)
<i>Hottip</i>-Mediated R-Loops Regulate CTCF TAD Boundary to Control WNT/b-Catenin Pathway in AML Genome
Authors: Huacheng Luo, Ganqian Zhu, Xiaoyan Ma, David F. Claxton, Yi Qiu, Mingjiang Xu, Suming Huang
Journal: Blood (2020)
Multiple Tissue Biomarkers Independently and Additively Predict Prostate Cancer Pathology Outcomes
Authors: Matthew R. Cooperberg, Janet E. Cowan, Karla J. Lindquist, Yasuko Kobayashi, Jeffry P. Simko, Henrik Bengtsson, Khushboo Singh, Vy Ngo, Andrew Avila, Lisa F. Newcomb, Maria Tretriakova, Daniel W. Lin, Steven Stone, Peter R. Carroll, Pamela L. Paris
Journal: European Urology (2020)
Tuberculosis prevention in children: a prospective community-based study in South Africa
Authors: Anna M. Mandalakas, Anneke C. Hesseling, Alexander Kay, Karen Du Preez, Leonardo Martinez, Lena Ronge, Andrew DiNardo, Christoph Lange, H. Lester Kirchner
Journal: European Respiratory Journal (2020)

Tuberculosis (TB) preventive therapy reduces TB risk in children. However, the effectiveness of TB preventive therapy in children living in high TB burden settings is unclear. In a prospective observational community-based cohort study in Cape Town, South Africa, we assessed the effectiveness of routine TB preventive therapy in children ≤15 years of age in a high TB and HIV prevalence setting. Among 966 children (median (interquartile range) age 5.07 (2.52–8.72) years), 676 (70%) reported exposure to an adult with TB in the past 3 months and 240 out of 326 (74%) eligible children initiated isoniazid preventive therapy under programmatic guidelines. Prevalent (n=73) and incident (n=27) TB were diagnosed among 100 out of 966 (10%) children. Children who initiated isoniazid preventive therapy were 82% less likely to develop incident TB than children who did not (adjusted OR 0.18, 95% CI 0.06–0.52; p=0.0014). Risk of incident TB increased if children were &lt;5 years of age, living with HIV, had a positive Mycobacterium tuberculosis -specific immune response or recent TB exposure. The risk of incident TB was not associated with sex or Mycobacterium bovis bacille Calmette–Guérin vaccination status. Number needed to treat (NNT) was lowest in children living with HIV (NNT=15) and children &lt;5 years of age (NNT=19) compared with children of all ages (NNT=82). In communities with high TB prevalence, TB preventive therapy substantially reduces the risk of TB among children who are &lt;5 years of age or living with HIV, especially those with recent TB exposure or a positive M. tuberculosis -specific immune response in the absence of disease.
Myeloid-Specific SHP-2 Ablation Induces Robust Anti-Tumor Immunity That Is Not Further Enhanced By PD-1 Blockade
Authors: Anthos Christofides, Natalia M Tijaro-Ovalle, Halil-Ibrahim Aksoylar, Rinku Pal, Abdelrahman AA Mahmoud, Laura Strauss, Nikolaos Patsoukis, Vassiliki A Boussiotis
Journal: Blood (2020)
Development and Analysis of a Weighed Prognostic Model in Newly Diagnosed Multiple Myeloma Patients
Authors: Xue-Han Mao, Yan Xu, Yuting Yan, Jiahui Liu, Huishou Fan, Weiwei Sui, Shuhui Deng, Chenxing Du, Dehui Zou, Lugui Qiu, Gang An
Journal: Blood (2020)