tbuckley/cabot-search huggingface dataset:
Characteristics and Outcomes of Recipients of Heart Transplant With Coronavirus Disease 2019
Authors: Farhana Latif, Maryjane A. Farr, Kevin J. Clerkin, Marlena V. Habal, Koji Takeda, Yoshifumi Naka, Susan Restaino, Gabriel Sayer, Nir Uriel
Journal: JAMA Cardiology (2020)

<h3>Importance</h3> Recipients of heart transplant (HT) may be at increased risk of adverse outcomes attributable to infection with coronavirus disease 2019 (COVID-19) because of multiple comorbidities and clinically significant immunosuppression. <h3>Objective</h3> To describe the characteristics, treatment, and outcomes of recipients of HT with COVID-19. <h3>Design, Setting, and Participants</h3> This case series from a single large academic heart transplant program in New York, New York, incorporates data from between March 1, 2020, and April 24, 2020. All recipients of HT followed up by this center who were infected with COVID-19 were included. <h3>Interventions</h3> Heart transplant and a confirmed diagnosis of COVID-19. <h3>Main Outcomes and Measures</h3> The primary measure was vital status at end of study follow-up. Secondary measures included patient characteristics, laboratory analyses, changes to immunosuppression, and treatment administered for COVID-19. <h3>Results</h3> Twenty-eight patients with HT received a confirmed diagnosis of COVID-19. The median age was 64.0 (interquartile range [IQR], 53.5-70.5) years, 22 (79%) were men, and the median time from HT was 8.6 (IQR, 4.2-14.5) years. Comorbid conditions included hypertension in 20 patients (71%), diabetes in 17 patients (61%), and cardiac allograft vasculopathy in 16 patients (57%). Twenty-two participants (79%) were admitted for treatment, and 7 (25%) required mechanical ventilation. Most (13 of 17 [76%]) had evidence of myocardial injury (median high-sensitivity troponin T, 0.055 [IQR, 0.0205-0.1345] ng/mL) and elevated inflammatory biomarkers (median peak high-sensitivity C-reactive protein, 11.83 [IQR, 7.44-19.26] mg/dL; median peak interleukin 6, 105 [IQR, 38-296] pg/mL). Among patients managed at the study institution, mycophenolate mofetil was discontinued in 16 patients (70%), and 6 (26%) had a reduction in the dose of their calcineurin inhibitor. Treatment of COVID-19 included hydroxychloroquine (18 patients [78%]), high-dose corticosteroids (8 patients [47%]), and interleukin 6 receptor antagonists (6 patients [26%]). Overall, 7 patients (25%) died. Among 22 patients (79%) who were admitted, 11 (50%) were discharged home, 4 (18%) remain hospitalized at the end of the study, and 7 (32%) died during hospitalization. <h3>Conclusions and Relevance</h3> In this single-center case series, COVID-19 infection was associated with a case fatality rate of 25% in recipients of HT. Immunosuppression was reduced in most of this group of patients. Further study is required to evaluate the optimal approach to management of COVID-19 infection in the HT population.
Deep learning for dermatologists: Part I. Fundamental concepts
Authors: Dennis H. Murphree, Pranav Puri, Huma Shamim, Spencer A. Bezalel, Lisa A. Drage, Michael Wang, Mark R. Pittelkow, Rickey E. Carter, Mark D.P. Davis, Alina G. Bridges, Aaron R. Mangold, James A. Yiannias, Megha M. Tollefson, Julia S. Lehman, Alexander Meves, Clark C. Otley, Olayemi Sokumbi, Matthew R. Hall, Nneka Comfere
Journal: Journal of the American Academy of Dermatology (2020)
ENDOSCOPIC ULTRASOUND-GUIDED PLACEMENT OF HOT AXIOS STENT FOR DRAINAGE OF WALLED-OFF PANCREATIC NECROSIS: A CASE SERIES
Authors: E Stratigakos, K Rosiou, MT Koutroumpi, G Andrianakou, E Karamintziou, E Ionas, I Karoumpalis, B Ntelis
Journal: Endoscopy (2020)

Aims The aim of this study was to evaluate the safety and clinical efficacy of Hot AXIOS stent for drainage of walled-off pancreatic necrosis (WON).
Analysis of the Potential Effect of Ponatinib on the QTc Interval in Patients with Refractory Hematologic Malignancies
Authors: Daryl Sonnichsen, David Dorer, Jorge E. Cortes, Moshe Talpaz, Michael W. Deininger, Neil Shah, Hagop M. Kantarjian, Dale Bixby, Michael J. Mauro, Ian W. Flinn, Jeffrey Litwin, Christopher D. Turner, Frank Haluska
Journal: Blood (2011)
Care Management for Low-Risk Patients with Heart Failure
Authors: Robert Frank DeBusk, Nancy Houston Miller, Kathleen Marie Parker, Albert Bandura, Helena Chmura Kraemer, Daniel Joseph Cher, Jeffrey Alan West, Michael Bruce Fowler, George Greenwald
Journal: Annals of Internal Medicine (2004)

In this clinical trial, nurse care management for patients with heart failure at low risk for rehospitalization did not reduce rehospitalizations for heart failure or for any cause. Most care manag...
Easier access to mechanical ventilation worldwide: an urgent need for low income countries, especially in face of the growing COVID-19 crisis
Authors: Claude Guérin, Patrick Lévy
Journal: European Respiratory Journal (2020)

<b>Combining easy-to-build noninvasive ventilator and open-source hardware description, may allow for adequate availability of ventilators to patients in low- and middle-income countries. This is urgently needed in the growing COVID-19 epidemic.</b>https://bit.ly/3f8ZkUR
SPIRITUALISM AND INSANITY.
Authors: Dudley Wright
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Twenty-four–Hour Intraocular Pressure–Related Patterns from Contact Lens Sensors in Normal-Tension Glaucoma and Healthy Eyes
Authors: Yong Woo Kim, Jin-Soo Kim, Sang Yoon Lee, Ahnul Ha, Jinho Lee, Young Joo Park, Young Kook Kim, Jin Wook Jeoung, Ki Ho Park
Journal: Ophthalmology (2020)
CIRCUMFERENTIAL ESD FOR SQUAMOUS OESOPHAGEAL NEOPLASIA USING THE DOUBLE TUNNEL AND DOUBLE TRACTION METHOD APPLIED ON BOTH PILLARS: AN ORGAN PRESERVING PROCEDURE
Authors: M Fraile-López, AP Blanco
Journal: Endoscopy (2020)

Esophageal endoscopic submucosal dissection (ESD) is technically challenging, even more if the lesion is broad and a circumferential resection is needed to perform a complete resection. In this case, we report a succcessful circumferential oesophageal ESD using the double tunnel and double clip-band line traction method, applying the traction on both pillars. With this strategy, the submucosa tissue is greatly exposed facilitating dissection. ESD was successfully completed using dual knife and SB knife achieving “en bloc” resection. The specimen showed a SCC with invasion of the lamina propria (T1,R0). A stenosis ocurred and was endoscopically treated.
NONINVASIVE MARKERS PREDICTING THE PRESENCE OF SIGNIFICANT OESOPHAGEAL VARICES IN CIRRHOTIC PATIENTS
Authors: S Mrabet, I Akkari, EB Jazia
Journal: Endoscopy (2020)

Aims According to the recommendations of Baveno VI, screening for oesophageal varices (OV) is recommended in patients with thrombocytopenia less than 150 000 elements/mm3 and/or an elasticity greater than 20 Kpa in the fibroscan. The purpose of our study was to determine noninvasive markers associated with the presence of significant VO (grade 2 or 3) at the time of diagnosis of cirrhosis
Abstract 13963: Type 2 Myocardial Infarction: Incidence, Risk Factors, and Outcomes Among 41,581 Patients Enrolled in 3 Large Randomized Clinical Trials
Authors: Chiara Melloni, Karen P Alexander, Angie Wu, W. Schuyler Jones, Rajendra H Mehta, Robert W Harrison, David Kong, Robin Mathews, Thomas J Povsic, Manesh R Patel, Sana M Al-Khatib, Kenneth Mahaffey, Rury Holman, Renato D Lopes
Journal: Circulation (2019)

Introduction: Type 2 myocardial infarction (MI), defined as myocardial necrosis due to myocardial supply and/or demand imbalance, is an increasingly recognized diagnosis that still lacks proper cli...
ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY IN PATHOLOGYLITHIASIS: WHAT RESULTS IN PATIENTS OVER THE AGE OF 75?
Authors: I Elkoti, S Lmrabti, K Loubaris, H Boutalaka, T Adajou, O Mohamed, A Sair, A Bendehmane, R Berraida, S Sentissi, H Seddik, A Benkirane
Journal: Endoscopy (2020)

Aims In front of an increasingly aging population, the ERCP raises the question of benefit in the elderly. So we set ourselves the goal of comparing ERCP results in lithiasis pathology in elderly patients respectively less and more than 75 years old.
DUODENAL EVALUATION IN ADENOMATOUS POLYPOSIS - IS THERE ANY ROLE FOR TAILORING SURVEILLANCE?
Authors: C Pinto, I Sá, I Pita, M Dinis-Ribeiro, C Brandão
Journal: Endoscopy (2020)

Aims Familial Adenomatous Polyposis (FAP) and MUTYH-Associated Polyposis (MAP) are associated with a high risk of small bowel lesions both in duodenum, ampulla and distally in the jejunum and ileon. Our aim was to evaluate the correlation between the severity of duodenal polyposis and the presence of ampullary adenoma and small-bowel polyps.
Abstract 10619: Oral Anticoagulant for Atrial Fibrillation in Patients on Dialysis: Insights From a Network Meta-analysis
Authors: Toshiki Kuno, Hisato Takagi, Tomo Ando, Takehiro Sugiyama, Satoshi Miyashita, Nelson Valentin, Yuichi J Shimada, Masaki Kodaira, Yohei Numasawa, Alexandros Briasoulis, Alfred Burger, Sripal Bangalore
Journal: Circulation (2019)

Background: Patients on dialysis are at increased risk of bleeding, hence the net clinical benefit of oral anticoagulation in the setting of atrial fibrillation (AF) remains uncertain. Our aim of t...
ENDOSCOPIC MANAGEMENT OF LARGE SYMPTOMATIC COLON LIPOMAS: A SYSTEMATIC REVIEW AND META-ANALYSIS
Authors: AM Vandenbroucke, M Bronswijk
Journal: Endoscopy (2020)

Aims Various techniques have been described for endoscopic treatment of large symptomatic colon lipomas. On of these techniques, lipoma unroofing, relies on spontaneous intraluminal expulsion, occurring after simple partial snare resection. This approach might provide a safer, easier and more cost effective technique compared to dissection-based techniques, endoscopic mucosal resection (EMR) or loop-assisted resection (LAR). Our aim was to compare efficacy and safety of unroofing with these three endoscopic techniques.
Prognostic role of pretreatment lactate dehydrogenase in patients with metastatic renal cell carcinoma: A systematic review and meta-analysis
Authors: Nandong Zhang, Hongna Zhang, Daqing Zhu,  JiRiGaLa, Dahai Yu, Chaoqi Wang,  WuYunBiLiGe,  Amin,  ZhiHong, Huichong Yu, Xiangbao Chen, Min Wang
Journal: International Journal of Surgery (2020)
A NEW 12-FRENCH PLASTIC STENT MAY BE AN ALTERNATIVE TO METALLIC STENTS IN UNRESECTABLE DISTAL MALIGNANT BILIARY OBSTRUCTION
Authors: E Pérez-Cuadrado-Robles, TG Moreels, T Aouattah, H Piessevaux, PH Deprez
Journal: Endoscopy (2020)

Aims To address the efficacy and safety of a new 12-French plastic stent (PS) in unresectable distal malignant biliary obstruction (DMBO).
KEY FACTORS LEADING TO INCOMPLETE BILIARY STONES CLEARANCE DURING THEIR FIRST ERCP IN PATIENTS WITH NAïVE PAPILLA
Authors: AJ del Pozo-Garcia, DR de la Cruz, FS Gómez, JC Marín-Gabriel, S Sáenz-López, L Ballesteros, MP Carreras, LL Couceiro, B Labrador, R Uribarrena
Journal: Endoscopy (2020)

Aims ERCP is currently the standard of care for the management of bile duct stones. The clearance of bile duct stones has improved with techniques as endoscopic papillary large balloon dilation (PLBD) or the novel intraductal therapies based on peroral cholangioscopy (POC), but reports about large stones clearance scarce.
CRISPR Screens Identify Essential Cell Growth Mediators in BRAF Inhibitor-Resistant Melanoma
Authors: Ziyi Li, Binbin Wang, Shengqing Gu, Peng Jiang, Avinash Sahu, Chen-Hao Chen, Tong Han, Sailing Shi, Xiaoqing Wang, Nicole Traugh, Hailing Liu, Yin Liu, Qiu Wu, Myles Brown, Tengfei Xiao, Genevieve M. Boland, X. Shirley Liu
Journal: Genomics Proteomics & Bioinformatics (2020)

Abstract BRAF is a serine/threonine kinase that harbors activating mutations in ∼7% of human malignancies and ∼60% of melanomas. Despite initial clinical responses to BRAF inhibitors, patients frequently develop drug resistance. To identify candidate therapeutic targets for BRAF inhibitor resistant melanoma, we conduct CRISPR screens in melanoma cells harboring an activating BRAF mutation that had also acquired resistance to BRAF inhibitors. To investigate the mechanisms and pathways enabling resistance to BRAF inhibitors in melanomas, we integrate expression, ATAC-seq, and CRISPR screen data. We identify the JUN family transcription factors and the ETS family transcription factor ETV5 as key regulators of CDK6, which together enable resistance to BRAF inhibitors in melanoma cells. Our findings reveal genes contributing to resistance to a selective BRAF inhibitor PLX4720, providing new insights into gene regulation in BRAF inhibitor resistant melanoma cells.
Erratum: Regulation of naive T cell function by the NF-κB pathway (Nature Immunology (2006) vol. 7 (763-772))
Authors: D Skokos, G Shakhar, R Varma, J C Waite, T O Cameron, R L Lindquist, T Schwickert, M C Nussenzweig, M L Dustin
Journal: Nature Immunology (2007)
SIDE-FENESTRATED VS. FORK-TIP NEEDLES FOR EUS-GUIDED FINE-NEEDLE BIOPSY OF SOLID PANCREATIC LESIONS: A PROSPECTIVE SINGLE CENTER RANDOMIZED STUDY
Authors: SF Crinò, M LeGrazie, MCC Bellocchi, L Bernardoni, E Manfrin, A Granato, F Locatelli, A Gabbrielli
Journal: Endoscopy (2020)

Aims To compare the performance of EUS-FNB using the SharkCore needle (SC) or the ProCore needle (PC) for the diagnosis of solid pancreatic lesions (SPLs).
DUODENOSCOPE-RELATED INFECTIONS: AN ITALIAN PICK IN 2019
Authors: A Fugazza, L Lamonaca, C Alvisi, G Aragona, M Ayoubi, M Bassi, A Benedetti, P Beretta, MB Canani, C Calcara, A Cambareri, L Camellini, ML Canfora, P Cantù, G Cengia, F Cereatti, G Costamagna, L Cugia, CD Angelis, FD Grazia, GDV Blanco, ED Giulio, G Diamantis, M Dinelli, C Fabbri, G Feliciangeli, A Gabbrielli, P Gambitta, C Luigiano, G Macarri, G Manes, G Manfredi, M Manno, N Mantovani, A Mariani, E Masci, G Missale, P Mosca, A Mussetto, M Mutignani, P Occhipinti, M Paganelli, MC Parodi, F Radaelli, R Salerno, M Traina, A Tringali, G Venezia, A Anderloni, A Repici
Journal: Endoscopy (2020)

Aims ERCP is performed with reusable duodenoscopes after manual and automated reprocessing. Recently, multidrug-resistant infection outbreaks associated with infected duodenoscopes have been reported. Our aim was to investigate the current Italian experience with duodenoscope-related infections and assess the criticality of the risk.
PERINEURAL INVASION PREDICTS POOR PROGNOSIS IN STAGE I-III COLORECTAL CANCER PATIENTS
Authors: MS Lalosevic, Z Krivokapic, M Micev, M Stojkovic, S Dragasevic, L Toncev, M Stulic, N Pejic, K Jankovic, D Culafic, I Jovanovic, AP Markovic
Journal: Endoscopy (2020)

Aims Colorectal cancer (CRC) is one of the most common diagnosed cancer, and one of the major causes of cancer-related deaths Worldwide. Current treatment guidelines mostly rely on TNM classification; however recent studies suggest that additional histopathological findings could affect the disease course. Clinical significance of perineural invasion (PNI) and lymphovascular invasion (LVI) in CRC patients is still controversial. Our aim was to determine whether PNI alone or associated with LVI have an effect on 5-year overall survival (OS) of CRC patients.
Proprotein Convertase Subtilisin/Kexin Type 9 Monoclonal Antibodies for Acute Coronary Syndrome
Authors: Eliano P. Navarese, Michalina Kołodziejczak, Dean J. Kereiakes, Udaya S. Tantry, Christopher O'Connor, Paul A. Gurbel
Journal: Annals of Internal Medicine (2016)

This narrative review describes the influence of proprotein convertase subtilisin/kexin type 9 antibodies on plaque composition and instability and posits a rationale for their use in patients with...
COLONOSCOPY QUALITY ASSURANCE IN AN ORGANIZED FIT-BASED COLORECTAL CANCER SCREENING PROGRAM
Authors: MCW. Spaander, PHA Wisse, SY de Boer, B den Hartog, M. Oudkerk Pool, JST Sive Droste, C. Verveer, FG van Maaren-Meijer, E Dekker
Journal: Endoscopy (2020)

Aims High quality colonoscopy is essential for optimal performance of a colorectal cancer (CRC) screening program. Therefore, endoscopists performing within the Dutch CRC screening program have to receive accreditation and fulfill minimum standards. In this study we assessed the quality of colonoscopies performed by the certified endoscopists.
POST-CHOLECYSTECTOMY CLIP AS A NIDUS FOR COMMON BILE DUCT STONE FORMATION
Authors: I Miguel, E Pijoan, N Torres, S Bazaga, G Torres, N Zaragoza, J Mª Miñana, J Garreta, J Mª Reñe, F Gonzalez-Huix
Journal: Endoscopy (2020)

86-year-old woman who underwent cholecystectomy and ERCP for choledocholithiasis performing sphincterotomy and stone extraction. She presented to our center for epigastric pain without infection signs, finding common bile duct (CBD) dilatation and choledocholithiasis in MR-cholangiopancreatography. ERCP was performed, finding dilatation of common bile duct (15-17mm) and a 12-15mm stone with radiopaque content like surgical clips, being unable to define if it was in CBD or cystic duct. After failed attempt of standard stone extraction, an endoscopic papillary large-balloon dilatation was performed and stone removed with balloon catheter. Stone was recovered and analysed, confirming the presence of a surgical clip inside.
Validity and utility of Hierarchical Taxonomy of Psychopathology (HiTOP): I. Psychosis superspectrum
Authors: Roman Kotov, Katherine G. Jonas, William T. Carpenter, Michael N. Dretsch, Nicholas R. Eaton, Miriam K. Forbes, Kelsie T. Forbush, Kelsey Hobbs, Ulrich Reininghaus, Tim Slade, Susan C. South, Matthew Sunderland, Monika A. Waszczuk, Thomas A. Widiger, Aidan G.C. Wright, David H. Zald, Robert F. Krueger, David Watson
Journal: World Psychiatry (2020)

The Hierarchical Taxonomy of Psychopathology (HiTOP) is a scientific effort to address shortcomings of traditional mental disorder diagnoses, which suffer from arbitrary boundaries between psychopathology and normality, frequent disorder co-occurrence, heterogeneity within disorders, and diagnostic instability. This paper synthesizes evidence on the validity and utility of the thought disorder and detachment spectra of HiTOP. These spectra are composed of symptoms and maladaptive traits currently subsumed within schizophrenia, other psychotic disorders, and schizotypal, paranoid and schizoid personality disorders. Thought disorder ranges from normal reality testing, to maladaptive trait psychoticism, to hallucinations and delusions. Detachment ranges from introversion, to maladaptive detachment, to blunted affect and avolition. Extensive evidence supports the validity of thought disorder and detachment spectra, as each spectrum reflects common genetics, environmental risk factors, childhood antecedents, cognitive abnormalities, neural alterations, biomarkers, and treatment response. Some of these characteristics are specific to one spectrum and others are shared, suggesting the existence of an overarching psychosis superspectrum. Further research is needed to extend this model, such as clarifying whether mania and dissociation belong to thought disorder, and explicating processes that drive development of the spectra and their subdimensions. Compared to traditional diagnoses, the thought disorder and detachment spectra demonstrated substantially improved utility: greater reliability, larger explanatory and predictive power, and higher acceptability to clinicians. Validated measures are available to implement the system in practice. The more informative, reliable and valid characterization of psychosis-related psychopathology offered by HiTOP can make diagnosis more useful for research and clinical care.
ENDOSCOPIC TREATMENT OF RECTAL ANASTOMOTIC DEHISCENCES - SINGLE-CENTRE EXPERIENCE
Authors: J Cortez-Pinto, I Rosa, SM Ferro, I Marques, J Moleiro, R Barroca, M Limbert, J Maciel, L d´Orey, AD Pereira
Journal: Endoscopy (2020)

Aims Advances in rectal carcinoma surgery have dramatically increased the number of sphincter-saving procedures. However, an increase in anastomotic dehiscences (AD) was concomitantly observed.
GASTRIC PERORAL ENDOSCOPIC PYLOROMYOTOMY FOR THE TREATMENT OF REFRACTORY GASTROPARESIS: A SYSTEMATIC REVIEW AND META-ANALYSIS
Authors: C Zhong, S Tan, Y Peng, X Tang
Journal: Endoscopy (2020)

Aims Gastric peroral endoscopic pyloromyotomy (G-POEM) is a novel minimally invasive intervention for treating refractory gastroparesis. We conducted a systematic review and meta-analysis to determine the clinical success and safety of G-POEM.
ESTIMATING THE GLOBAL PREVALENCE OF BARRETT’S ESOPHAGUS: A SYSTEMATIC REVIEW OF PUBLISHED STUDIES
Authors: I Marques de Sá, P Marcos, P Sharma, MD Ribeiro
Journal: Endoscopy (2020)

Aims Determining the prevalence of Barrett’s esophagus (BE) is of paramount importance for defining screening strategies and health-services resource utilization. However, precise estimates of prevalence are not clear with existing published data reporting a wide range of prevalence. We aimed to synthesize the available data, determine BE prevalence and assess variability according to definition (namely to the most recent guidelines), geographical region, time period and methodology.
Candidatus Rickettsia tarasevichiae Infection in Eastern Central China
Authors: Wei Liu, Hao Li, Qing-Bin Lu, Ning Cui, Zhen-Dong Yang, Jian-Gong Hu, Ya-Di Fan, Chen-Tao Guo, Xiao-Kun Li, Ya-Wei Wang, Kun Liu, Xiao-Ai Zhang, Lan Yuan, Pu-Yu Zhao, Shu-Li Qin, Wu-Chun Cao
Journal: Annals of Internal Medicine (2016)

Severe fever with thrombocytopenia syndrome (SFTS) is caused by a tick-borne virus that is now endemic in eastern China. The authors investigated whether another emerging pathogen, Candidatus Ricke...
MHC-peptide specific antibodies reveal inefficient presentation of an antigenic Melan-A derived peptide after active intracellular processing
Authors: G Held, C Zwick, G Stewart-Jones, M Thiel, F Levy, D Dieckmann, G Schuler, B Kubuschok, H R Hoogenboom, V Cerundolo, M Pfreundschuh, C Renner
Journal: Cancer Research (2006)
SMALL BOWEL ANGIOECTASIA ARE A MARKER OF FRAILTY AND CARRY A POOR PROGNOSIS
Authors: A Robertson, M Davie, A Koulaouzidis, J Plevris
Journal: Endoscopy (2020)

Aims This study aims to establish the 5-year survival of those diagnosed with bleeding small bowel (SB) angioectasia, with the hypothesis that many will suffer deaths relating to comorbidity rather than GI bleeding.
Long-Term Efficacy of Dapagliflozin in Patients With Type 2 Diabetes Mellitus Receiving High Doses of Insulin
Authors: John P.H. Wilding, Vincent Woo, Norman G. Soler, Andrea Pahor, Jennifer Sugg, Katja Rohwedder, Shamik Parikh
Journal: Annals of Internal Medicine (2012)

Persons with type 2 diabetes may have inadequate glycemic control despite high insulin doses, and increasing insulin doses can cause adverse effects. Dapagliflozin inhibits renal absorption of gluc...