tbuckley/cabot-search huggingface dataset:
Comparison Between Wilms' Tumor 1 (WT1) Expression Using a Standardized European Leukemia Net (ELN)-Certified Assay and Other Methods for Detection of Minimal Residual Disease (MRD) in MDS and AML Patients after Allogeneic Blood Stem Cell Transplantation
Authors: Christina Rautenberg, Sabrina Pechtel, Barbara Hildebrandt, Beate Betz, Ariane Dienst, Kathrin Nachtkamp, Stefanie Geyh, Pia Verena Schmidt, Claudia Heyn, Mustafa Kondakci, Norbert Gattermann, Rainer Haas, Ulrich Germing, Guido Kobbe, Thomas Schroeder
Journal: Blood (2016)
Plerixafor Plus G-CSF Is An Effective Regimen to Mobilize Hematopoietic Stem Cells in NHL Patients with Circulating Peripheral Blood CD34+ Cells/μl &lt; 10.
Authors: Richard T. Maziarz, Ivana N Micallef, Patrick Stiff, Brian J. Bolwell, Sachin Marulkar, Gary C Calandra, John F. DiPersio
Journal: Blood (2009)
Novel Myeloma-Specific Multiple Peptides Able to Generate Cytotoxic T Lymphocytes: Potential Therapeutic Application in Multiple Myeloma and Other Plasma Cell Disorders,
Authors: Jooeun Bae, Ruben Carrasco, Ann-Hwee Lee, Rao Prabhala, Yu-Tzu Tai, Weihua Song, Kenneth C Anderson, Nikhil C. Munshi
Journal: Blood (2011)
Reduced Intensity (RI) Allogeneic Hematopoietic Cell Transplantation (HCT) Improves Outcomes for Older (≥ 60 Yrs) Patients (Pts) with Acute Myeloid Leukemia (AML).
Authors: Margaret R. O’Donnell, Anthony S. Stein, Ryotaro Nakamura, Marilyn L. Slovak, Nicole Tsai, Joycelynne Palmer, Roberto Rodriguez, Ricardo Spielberger, Eileen P. Smith, David S. Snyder, Pablo M. Parker, Leslie Popplewell, Vinod Pullarkat, Chatchada Karanes, Neil Kogut, George Somlo, Stephen J. Forman
Journal: Blood (2007)
Humanized Von Willebrand Factor-Glycoprotein Ibα Interaction in Mouse Models of Hemostasis and Thrombosis
Authors: Sachiko Kanaji, Jennifer N Orje, Yuichi Kamikubo, Taisuke Kanaji, Jeremy Mattson, Alessandro Zarpellon, Scot A. Fahs, Rashmi Sood, Sandra L Haberichter, Zaverio M. Ruggeri, Robert R Montgomery
Journal: Blood (2016)
MLL Gene Rearrangements in 174 Infants with Acute Leukemia.
Authors: Grigory Tsaur, Alexander Popov, Elena Fleishman, Olga Sokova, Anna Demina, Tatyana Gindina, Olga Kalennik, Anatoly Kustanovich, Irina Martynkevich, Tatyana Nasedkina, Yulia Olshanskaya, Vanik Ovsepyan, Olga Plekhanova, Tatyana Riger, Leonid Saveliev, Irina Shmunk, Egor Shorikov, Olga Streneva, Margarita Strigaleva, Tatyana Verzhbitskaya, Alena Volochnik, Claus Meyer, Rolf Marschalek, Larisa Fechina
Journal: Blood (2012)
Scheduled cessation in treatment using lenvatinib for differentiated thyroid carcinoma
Authors: Yasuhiro Ito, Toshihiko Kasahara, Akihiro Miya, Naomi Kiyota, Hiroo Masuoka, Tomohiko Nakamura, Waka Yoshioka, Ito Mitsuru, Akira Miyauchi
Journal: Annals of Oncology (2019)
Lower Use of DLI Post Relapse of Malignancy May Result in Shorter Post-Relapse Survival (PRS) in Patients Undergoing T Cell Replete Haploidentical Donor Transplantation (HIDT) Versus Matched Related (MRD) or Matched Unrelated Donor (MUD) Hematopoietic Cell Transplantation (HCT)
Authors: Melhem Solh, Xu Zhang, Stacey Brown, Lawrence E. Morris, H. Kent Holland, Scott R. Solomon, Asad Bashey
Journal: Blood (2015)
Targeted Next-Generation Sequencing and Genome-Wide High-Resolution Copy Number DNA Arrays Allow the Identification of Five Novel RUNX1 Fusions In Hematological Malignancies.
Authors: Vera Grossmann, Alexander Kohlmann, Hans-Ulrich Klein, Sonja Schindela, Susanne Schnittger, Martin Dugas, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach
Journal: Blood (2010)
Chromosomal Abnormalities in Transformed Ph-Negative Myeloproliferative Neoplasm Are Independent of the JAK2 and the TET2 Statuses.
Authors: Florence Nguyen-Khac, Lucile Couronne, Virginie Eclache, Joris Andrieux, Eric Lippert, Olivier Kosmider, Francine Mugneret, Marie-Agnes Collonge-Rame, Dominique Penther, Marina Lafage, Nathalie Gachard, Nathalie Nadal, Marie-Joelle Mozziconacci, Nicole Dastugue, Chrystele Bilhou-Nabera, Stephanie Struski, Christine Cabrol, Isabelle Radford-Weiss, Claude Lesty, Olivier A Bernard
Journal: Blood (2009)
Targeting of Chronic Lymphocytic Leukemia B Cells with a Novel Monoclonal Antibody to ROR1
Authors: Bing CUi, George F. Widhopf, Jian Yu, Daniel Martinez, Esther Avery, Suping Zhang, Liguang Chen, Rongrong Wu, Christina C.N. Wu, Charles Prussak, Thomas J. Kipps
Journal: Blood (2011)
Generation and Functional Analysis of Congenital Dyserythropoietic Anemia (CDA) Patient-Specific Induced Pluripotent Stem Cells
Authors: Hiroshi Kohara, Hiromi Ogura, Takako Aoki, Chika Sakamoto, Yoshie Ogawa, Shohei Miyamoto, Hitoshi Kanno, Kenzaburo Tani
Journal: Blood (2016)
SUSTAIN: A Multicenter, Randomized, Placebo-Controlled, Double-Blind, 12-Month Study to Assess Safety and Efficacy of SelG1 with or without Hydroxyurea Therapy in Sickle Cell Disease Patients with Sickle Cell-Related Pain Crises
Authors: Kenneth I. Ataga, Abdullah Kutlar, Julie Kanter, Darla Liles, Rodolfo Cancado, João Friedrisch, Troy H. Guthrie, Jennifer Knight-Madden, Ofelia A. Alvarez, Victor R. Gordeuk, Sandra Gualandro, Marina Pereira Collela, Wally R. Smith, Scott A. Rollins, Jonathan W. Stocker, Russell P. Rother
Journal: Blood (2016)
Clinical Relevance of Minimal Residual Disease Monitoring in NPM1 Mutated AML: A Study of the AML Study Group (AMLSG)
Authors: Silke Kapp-Schwoerer, Andrea Corbacioglu, Verena I. Gaidzik, Peter Paschka, Daniela Weber, Jan Kroenke, Maria-Veronica Teleanu, Gudrun Göhring, Brigitte Schlegelberger, Michael Luebbert, Thomas Kindler, Mohammad Amen Wattad, Andrea Kuendgen, David Nachbaur, Walter Fielder, Helmut Rainer Salih, Heinz A. Horst, Karin Tina Mayer, Katharina S. Götze, Martin Bentz, Jan Schleicher, Felicitas Thol, Michael Heuser, Jürgen Krauter, Arnold Ganser, Richard F. Schlenk, Hartmut Döhner, Konstanze Döhner
Journal: Blood (2015)
“Hiper CVAD Followed by Rituximab Purging Previous to Autologous Stem-Cell Transplantation as Therapy of Mantle Cell Lymphoma. Results of Manto 2000 study”.
Authors: F.J. Capote, Eva Gonzalez-Barca, Albert Oriol, Antonio Romero-Aguilar, Angel Leon, F.J. Fernandez-Calvo, Elena Pérez-Ceballos, Eva Donato, Dolores Caballero, Jose Antonio Queizán, María Jesus Peñarrubia, Luis Palomera, Julio Prieto, Pilar Giraldo, Juan Bergua
Journal: Blood (2009)
Fine Tuning of Surface CRLF2 Expression and Its Associated Signalling Profile in Childhood B Cell Precursor Acute Lymphoblastic Leukemia
Authors: Giuseppe Gaipa, Cristina Bugarin, Chiara Palmi, Jolanda Sarno, Angela Savino, Oscar Maglia, Geertruy te Kronnie, Giovanni Cazzaniga, Andrea Biondi
Journal: Blood (2012)
Survival after T-Cell Replete Haplo-Identical Related Donor Transplant Using Post-Transplant Cyclophosphamide Compared with Matched Unrelated Donor Transplant for Acute Myeloid Leukemia
Authors: Stefan O. Ciurea, Mei-Jie Zhang, Andrea Bacigalupo, Asad Bashey, Frederick R. Appelbaum, Joseph H. Antin, Junfang Chen, Steven M. Devine, Daniel H. Fowler, Ryotaro Nakamura, Miguel-Angel Perales, Sai Ravi Pingali, David L. Porter, Olle Ringdén, Vanderson Rocha, Ravi Vij, Daniel J. Weisdorf, Richard E. Champlin, Ephraim J. Fuchs, Mary Eapen
Journal: Blood (2014)
Impact of Complete Response on Survival with Either Autologous Stem Cell Transplantation or Conventional Chemotherapy: Results of a Pooled Analysis of 5 Phase III Trials in Newly Diagnosed Multiple Myeloma Patients
Authors: Roberto Mina, Alessandra Larocca, Massimo Offidani, Sara Bringhen, Tommaso Caravita, Valeria Magarotto, Lucia Pantani, Francesco Di Raimondo, Alberto Bosi, Iolanda D. Vincelli, Paola Tacchetti, Gianluca Gaidano, Sonia Grandi, Caterina Musolino, Chiara Cerrato, Ludek Pour, Monica Astolfi, Giuseppe Rossi, Fausto Rossini, Maria T. Petrucci, Roberto Ria, Annalisa Pezzi, Roman Hajek, Michele Cavo, Andrew Spencer, Mario Boccadoro, Antonio Palumbo
Journal: Blood (2015)
Survival after Relapse in Higher Risk Acute Lymphoblastic Leukemia (ALL) in Children and Adolescents Is Independent of Prior Treatment Intensity: A Report from the Children’s Oncology Group (COG).
Authors: David Robert Freyer, Nita L. Seibel, Mei K La, Meenakshi Devidas, William L. Carroll, Stephen P. Hunger, Paul S. Gaynon
Journal: Blood (2008)
Intrabone Injection of T-Cell Depleted Peripheral Blood Stem Cells from HLA-Haploidentical Donors to Reduce the Risk of Graft Rejection in Children
Authors: Luisa Strocchio, Marco Zecca, Patrizia Comoli, Perotti Cesare, Claudia Del Fante, Laura Rubert, Elena Bergami, Francesca Introzzi, Alessandra Tolva, Gianluca Viarengo, Franco Locatelli
Journal: Blood (2014)
Amino Acid Regions 572–579 and 657–666 of the Spacer Domain of ADAMTS13 Provide a Common Antigenic Core Required for Binding of Antibodies in Patients with Acquired TTP.
Authors: Brenda M. Luken, Ellen A.M. Turenhout, Paul H.P. Kaijen, Rob Fijnheer, Jan Voorberg
Journal: Blood (2005)
DNA methyltransferase inhibitors upregulate CD38 protein expression and enhance daratumumab efficacy in multiple myeloma
Authors: Priya Choudhry, Margarette C. Mariano, Huimin Geng, Thomas G. Martin, Jeffrey L. Wolf, Sandy W. Wong, Nina Shah, Arun P. Wiita
Journal: Leukemia (2019)

Author(s): Choudhry, Priya; Mariano, Margarette C; Geng, Huimin; Martin, Thomas G; Wolf, Jeffrey L; Wong, Sandy W; Shah, Nina; Wiita, Arun P
Palbociclib in clinical use for metastatic breast cancer at a single institution
Authors: Mitsuo Terada, Sawaki Masataka, Hattori Masaya, Yoshimura Akiyo, Gondo Naomi, Kotani Haruru, Adachi Yayoi, Kataoka Ayumi, Sugino Kayoko, Horisawa Nanae, Mori Makiko, Ozaki Yuri, Iwata Hiroji
Journal: Annals of Oncology (2019)
Nicotinamide N-Methyltransferase Expression Decreases in Iron Overload Exacerbating Iron-Induced Hepatotoxicity
Authors: Tiago De Bone Koppe, Bonnie Patchen, Aaron Cheng, Manoj Bhasin, Chris D. Vulpe, Jose M. Fernandez-Real, Robert K. Schwartz, Pavlos Pissios, Paula G. Fraenkel
Journal: Blood (2016)
hOCT1 Gene Expression Might Predict Molecular Response In Patients with Chronic Myeloid Leukemia
Authors: Lurdes Zamora, Marta Cabezon, Concha Boqué, Silvia Marce, Jordi Ribera, Diana Dominguez, Isabel Granada, Javier Grau, Blanca Xicoy, Cristalina Fernandez, Alberto Fernandez de Sevilla, David Gallardo, Josep-Maria Ribera, Fuensanta Millá, Evarist Feliu
Journal: Blood (2010)
Clinical Implications of PET-Negative Residual Disease At the Completion of Chemotherapy for Diffuse Large B-Cell Lymphoma
Authors: Bouthaina S. Dabaja, Jack Phan, L. Jeffrey Medeiros, F.B. Hagemeister, Hubert Chuang, Luis Fayad, Ferial Shihadeh, Pamela Allen, Christine Wogan, Maria A. Rodriguez
Journal: Blood (2011)
Outcomes of Transplantation with Matched-Related Donor (MRD) and Alternative Donor (AD) Stem Cells in Children with Severe Thalassemia.
Authors: Suradej Hongeng, Samart Pakakasama, Ampaiwan Chuansumrit, Nongnuch Sirachainan, Watana Chaisiripoomkere, Artit Ungkanont, Saengsuree Jootar
Journal: Blood (2004)
Monitoring Molecular Response, Minimal Residual Disease and Clonal Structures in Polycythemia Vera Patients Treated with Interferon Alpha
Authors: Roland Jäger, Edith Bogner, Kerstin Trenker, Michael Gurbisz, Bettina Gisslinger, Martin Schalling, Faith Hall-Glenn, Nicole C.C. Them, Christoph Klade, Heinz Gisslinger, Gregor Hoermann, Robert Kralovics
Journal: Blood (2016)
Value of Low Dose IL-2 as Maintenance Following Consolidation Treatment or Autologous Transplantation in Acute Myelogenous Leukemia (AML) Patients Aged 15-60 Years Who Reached CR After High Dose (HD-AraC) Vs Standard Dose (SD-AraC) Cytosine Arabinoside During Induction: Results of the AML-12 Trial of EORTC and GIMEMA Leukemia Groups.
Authors: Roelof Willemze, Stefan Suciu, Franco Mandelli, Stijn J.M. Halkes, Jean-Pierre Marie, Boris Labar, Adriano Venditti, Petra Muus, Martin Mistrik, Bruno Rotoli, Domenico Magro, Lorella Melillo, Dominique Bron, Francesco Fabbiano, Dominik L.D. Selleslag, Domenico Pastore, Silvia maria Trisolini, Paola Fazi, Christelle Vandermaelen, Liliana Baila, Marco Vignetti, Sergio Amadori, T. M. de Witte, Giovanna Meloni
Journal: Blood (2009)
Safety of two different doses of simvastatin plus rifaximin in decompensated cirrhosis (LIVERHOPE-SAFETY): a randomised, double-blind, placebo-controlled, phase 2 trial
Authors: Elisa Pose, Laura Napoleone, Ahmed Amin, Daniela Campion, César Jimenez, Salvatore Piano, Olivier Roux, Frank Erhard Uschner, Koos de Wit, Giacomo Zaccherini, Carlo Alessandria, Paolo Angeli, Mauro Bernardi, Ulrich Beuers, Paolo Caraceni, François Durand, Rajeshwar P Mookerjee, Jonel Trebicka, Victor Vargas, Raúl J Andrade, Marta Carol, Judit Pich, Juan Ferrero, Gema Domenech, Marta Llopis, Ferran Torres, Patrick S Kamath, Juan G Abraldes, Elsa Solà, Pere Ginès
Journal: The Lancet. Gastroenterology & hepatology (2019)
Disruption Of CD9 Expression Affects Adhesion, Migration and Engraftment Of Pre-B Lymphocytes
Authors: Marie-Pierre Arnaud, Audrey Vallée, Guillaume Robert, Anne-Gaelle Rio, Elisabetta Dondi, Jacinthe Bonneau, Christine LE ROY, Nadine Varin-Blank, Marie-Dominique Galibert, Marie-Bérengère Troadec, Virginie Gandemer
Journal: Blood (2013)
Impact of the Timing of Complete Remission and Transplantation on Estimates of Event-Free Survival in Acute Myeloid Leukemia
Authors: Jun Yin, Betsy R. Laplant, Geoffrey L. Uy, Guido Marcucci, William Blum, Richard A. Larson, Richard M. Stone, Sumithra Mandrekar
Journal: Blood (2016)
PD-L1 and PD-L2 Genetic Alterations Define Classical Hodgkin Lymphoma and Predict Outcome
Authors: Margaretha GM Roemer, Ranjana H Advani, Azra H. Ligon, Yasodha Natkunam, Robert A Redd, Heather Homer, Courtney Connelly, Heather H. Sun, Sarah E. Daadi, Bjoern Chapuy, Daphne de Jong, Richard T. Hoppe, Donna S Neuberg, Scott J Rodig, Margaret A. Shipp
Journal: Blood (2015)
Adoptive Immunotherapy with Autologous CD25-Depleted and CD3/CD28-Costimulated T-Cells (ACTC) Enhances Numeric and Functional Lymphocyte Recovery after Cyclophosphamide - Fludarabine Chemotherapy in Patients with Low-Grade Follicular Lymphoma.
Authors: Stephen J. Schuster, Bruce L. Levine, Sunita Nasta, Charalambos Andreadis, Anthony R. Mato, Nicole Aqui, Julio Cotte, Zhaohui Zheng, Andrea Cannon, Benjamin Musher, Bridget Fonash, Lisa H. Downs, Elizabeth Veloso, Carl H. June
Journal: Blood (2007)
Recognition of human gastrointestinal cancer neoantigens by circulating PD-1+ lymphocytes
Authors: Alena Gros, Eric Tran, Maria R. Parkhurst, Sadia Ilyas, Anna Pasetto, Eric M. Groh, Paul F. Robbins, Rami Yossef, Andrea Garcia-Garijo, Carlos A. Fajardo, Todd D. Prickett, Li Jia, Jared J. Gartner, Satyajit Ray, Lien Ngo, John R. Wunderllich, James C. Yang, Steven A. Rosenberg
Journal: Journal of Clinical Investigation (2019)

Tumor-resident lymphocytes can mount a response against neoantigens expressed in microsatellite-stable gastrointestinal (GI) cancers, and adoptive transfer of neoantigen-specific lymphocytes has demonstrated antitumor activity in selected patients. However, whether peripheral blood could be used as an alternative minimally invasive source to identify lymphocytes targeting neoantigens in patients with GI cancer with relatively low mutation burden is unclear. We used a personalized high-throughput screening strategy to investigate whether PD-1 expression in peripheral blood could be used to identify CD8+ or CD4+ lymphocytes recognizing neoantigens identified by whole-exome sequencing in 7 patients with GI cancer. We found that neoantigen-specific lymphocytes were preferentially enriched in the CD8+PD-1+/hi or CD4+PD-1+/hi subsets, but not in the corresponding bulk or PD-1- fractions. In 6 of 7 individuals analyzed we identified circulating CD8+ and CD4+ lymphocytes targeting 6 and 4 neoantigens, respectively. Moreover, neoantigen-reactive T cells and a T cell receptor (TCR) isolated from the CD8+PD-1+ subsets recognized autologous tumor, albeit at reduced levels, in 2 patients with available cell lines. These data demonstrate the existence of circulating T cells targeting neoantigens in GI cancer patients and provide an approach to generate enriched populations of personalized neoantigen-specific lymphocytes and isolate TCRs that could be exploited therapeutically to treat cancer.
Genetic Causes of Anemia in Malawian Children Less Than 5 Years of Age: Results from the Malawi Demographic and Health Survey
Authors: Patrick T. McGann, Anne M. Williams, Kathryn E. McElhinney, Laurel Romano, Julia Woodall, Thad A. Howard, Graham Ellis, Carine Mapango, Ben Chilima, Russell E. Ware, Parminder S. Suchdev
Journal: Blood (2016)
Prognostic Significance Of Systemic Inflammatory Factors In Patients With Diffuse Large B Cell Lymphoma Treated By R-CHOP
Authors: Kyung Ah Yoh, Ho Sup Lee, Lee Chun Park, Eun Mi Lee, Seong Hoon Shin, Byeong Jin Ye, Joon Ho Moon, Jae-Cheol Jo, Won Sik Lee, Ho-Jin Shin, Sun Young Oh, Yang Soo Kim
Journal: Blood (2013)
EBV-Specific CD8+ T-Cells Are Not Functionally Impaired in Chronic Lymphocytic Leukemia
Authors: Tom Hofland, Iris de Weerdt, Sanne Terpstra, Ester B.M. Remmerswaal, Ineke J.M. ten Berge, Arnon P. Kater, Sanne H. Tonino
Journal: Blood (2015)
Pacritinib, a Dual FLT3/JAK2 Inhibitor, Reduces Irak-1 Signaling in Acute Myeloid Leukemia
Authors: Megan M Cleary, Rhese Thompson, Shawn Mahmood, Monika Davare, Steve Kurtz, Johannes Elferich, Ujwal Shinde, Brian J. Druker, Jack Singer, Anupriya Agarwal
Journal: Blood (2015)
Modified SMILE in the Treatment of Natural Killer T-Cell Lymphoma, Nasal and Nasal Type: A Single Center US Experience
Authors: Matthew Alexander Lunning, Erika Pamer, Lauren Wintman, Valkal Bhatt, Joachim Yahalom, Alison J. Moskowitz, Jenna D Goldberg, David J. Straus, Paul Hamlin, Andrew D Zelenetz, Steven M. Horwitz
Journal: Blood (2011)
AT9283, a Small Molecule Multi-Targeted Kinase Inhibitor with Potent Activity Against Aurora Kinase and STAT3 In Combination with Lenalidomide Results In Synergistic Anti-Myeloma Activity
Authors: Loredana Santo, Teru Hideshima, Diana Cirstea, Madhavi L Bandi, Erik A Nelson, Hiroshi Ikeda, Sonia Vallet, Samantha Pozzi, Kishan Patel, Gullu Gorgun, Naoya Mimura, Claire Fabre, Yiguo Hu, Dharminder Chauhan, Matthew S Squires, Nikhil C. Munshi, Kenneth C. Anderson, Noopur Raje
Journal: Blood (2010)
A Phase II Study of Bortezomib-GIFOX (Gemcitabine, Ifosfamide, Oxaliplatin) in Patients with Newly Diagnosed Natural-Killer/T-Cell Lymphoma
Authors: Tiffany Tang, Kevin Tay, Miriam Tao, Richard Hong Hui Quek, Mohamad Farid, Soon Thye Lim
Journal: Blood (2016)
General and Organ Fat Assessed by Magnetic Resonance Imaging and Respiratory Outcomes in Childhood
Authors: Sara M. Mensink-Bout, Susana Santos, Evelien R. van Meel, Edwin H. G. Oei, Johan C. de Jongste, Vincent W. V. Jaddoe, Liesbeth Duijts
Journal: American Journal of Respiratory and Critical Care Medicine (2019)

Rationale: Obesity has been implicated as a pathogenic factor in asthma, but the underlying role of general and organ fat is unclear.Objectives: We hypothesized that organ fat, rather than the total fat mass, increases the risk of asthma.Methods: In a population-based prospective cohort study among 5,421 children aged 10 years, we measured general fat including body mass index and fat mass index by dual-energy X-ray absorptiometry, and organ fat including subcutaneous fat index, visceral fat index, pericardial fat index, and liver fat fraction by magnetic resonance imaging. Lung function was measured by spirometry. Current asthma was assessed by questionnaire.Measurements and Main Results: Higher body mass index and fat mass index were associated with higher FEV1 (z-score difference [95% confidence interval (CI)], 0.16 [0.14 to 0.19] and z-score difference [95% CI], 0.06 [0.03 to 0.09] per SD score increase, respectively), higher FVC (z-score difference [95% CI], 0.19 [0.17 to 0.22] and z-score difference [95% CI], 0.07 [0.04 to 0.10]), and lower FEV1/FVC ratio (z-score difference [95% CI], -0.07 [-0.10 to -0.05] and z-score difference [95% CI], -0.03 [-0.06 to -0.00]) but not with forced expiratory flow after exhaling 75% of FVC or asthma. Higher visceral fat index, independent of fat mass index, was associated with higher FVC (z-score difference [95% CI], 0.07 [0.03 to 0.10]), lower FEV1/FVC (z-score difference [95% CI], -0.05 [-0.09 to -0.01]), and higher risk of asthma (odds ratio, 1.20; 95% CI, 1.01 to 1.43 per SD score increase). No other organ fat measures were independently associated with lung function or asthma.Conclusions: The obesity-asthma link is driven mainly by visceral fat, independent of total fat mass; therefore, abdominal fat might contribute to asthma development.
Suppression of Mir-93 May Regulate Anti-Oxidant Metabolism in Mesenchymal Stromal Cells Derived From Acute Myeloid Leukemia Patients.
Authors: Peter P. Ruvolo, Rodrigo Jacamo, Teresa McQueen, Rongqing Pan, Ismael Samudio, Marina Konopleva, Steven M. Kornblau, Ramiro Garzon, Carlo M. Croce, Michael Andreeff
Journal: Blood (2012)
Activity of Yttrium 90 (90Y) Ibritumomab Tiuxetan (Zevalin®) in 22 Patients with Relapsed and Refractory Mantle Cell Lymphoma (MCL).
Authors: Anas Younes, Barbara Pro, Maria A. Rodriguez, Jorge E. Romaguera, Peter McLaughlin, Michael Wang, Fredrick B. Hagemeister, Nam H. Dang, Sattva Neelapu, Donald Podoloff
Journal: Blood (2005)
Relative RATIO Of BCR-ABL1 Transcript Clearance Improves The Prognostic VALUE Of Single PCR Assessment At The 3 and 6 Month Time Points In Patients With Chronic Myeloid Leukemia In Chronic PHASE Treated In The Dasision Study
Authors: Alfonso Quintás-Cardama, Sangbum Choi, Hagop M. Kantarjian, Xuelin Huang, Jorge E. Cortes
Journal: Blood (2013)
Decreased Incidence of Clonal Evolution to Myelodysplastic Syndrome with Monosomy 7 in Children with Aplastic Anemia Following Reduced Duration G-CSF Therapy and Early Indication for BMT from an Alternative Donor.
Authors: Hiroshi Yagasaki, Kudo Kazuko, Koji Kato, Kimikazu Matsumoto, Keizo Horibe, Seiji Kojima
Journal: Blood (2004)
Selective Inhibition of the Chymotrypsin-Like Activity of the Immunoproteasome and Constitutive Proteasome Represents a Valid Anti-Tumor Strategy in Waldenstrom Macroglobulinemia.
Authors: Aldo M. Roccaro, Antonio Sacco, Monette Aujay, Hai Ngo, Feda Azab, Abdel Kareem Azab, Molly Melhem, Judith M. Runnels, Phong Quang, Susan Demo, Irene Ghobrial
Journal: Blood (2009)