International Consensus Guidelines for Nonvariceal Gastrointestinal Bleeding: A Step Forward
Authors: Angel Lanas
Journal: Annals of Internal Medicine (2019)

Editorials3 December 2019International Consensus Guidelines for Nonvariceal Gastrointestinal Bleeding: A Step ForwardAngel Lanas, MDAngel Lanas, MDUniversity Clinic Hospital, University of Zaragoza, CIBERehd, IIS Aragón, Zaragoza, Spain (A.L.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/M19-2789 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Nonvariceal upper gastrointestinal bleeding (UGIB) is common, may be severe, and often requires urgent attention. In recent decades, worldwide rates of this disorder have decreased because of strategies to prevent gastrointestinal damage from nonsteroidal anti-inflammatory drugs and aspirin, therapies to eradicate Helicobacter pylori, and a lower prevalence of H pylori infection in the population (1). During the same period, new endoscopic and pharmacologic therapies improved the evidence-based care of patients with nonvariceal UGIB.Recently, an international multidisciplinary group of experts (2) updated the International Consensus Recommendations on the Management of Patients With Nonvariceal Upper Gastrointestinal Bleeding published in 2010 (3). ...References1. Lanas A, Dumonceau JM, Hunt RH, et al. Non-variceal upper gastrointestinal bleeding. Nat Rev Dis Primers. 2018;4:18020. [PMID: 29671413] doi:10.1038/nrdp.2018.20 CrossrefMedlineGoogle Scholar2. Barkun AN, Almadi M, Kuipers EJ, et al. Management of nonvariceal upper gastrointestinal bleeding: guideline recommendations from the International Consensus Group. Ann Intern Med. 2019;171:805-22. doi:10.7326/M19-1795 LinkGoogle Scholar3. Barkun AN, Bardou M, Kuipers EJ, et al; International Consensus Upper Gastrointestinal Bleeding Conference Group. International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding. Ann Intern Med. 2010;152:101-13. [PMID: 20083829]. doi:10.7326/0003-4819-152-2-201001190-00009 LinkGoogle Scholar4. Gralnek IM, Dumonceau JM, Kuipers EJ, et al. Diagnosis and management of nonvariceal upper gastrointestinal hemorrhage: European Society of Gastrointestinal Endoscopy (ESGE) guideline. Endoscopy. 2015;47:a1-46. [PMID: 26417980] doi:10.1055/s-0034-1393172 CrossrefMedlineGoogle Scholar5. Sung JJ, Chiu PW, Chan FKL, et al. Asia-Pacific Working Group consensus on non-variceal upper gastrointestinal bleeding: an update 2018. Gut. 2018;67:1757-1768. [PMID: 29691276] doi:10.1136/gutjnl-2018-316276 CrossrefMedlineGoogle Scholar6. Bhatt DL, Cryer BL, Contant CF, et al; COGENT Investigators. Clopidogrel with or without omeprazole in coronary artery disease. N Engl J Med. 2010;363:1909-17. [PMID: 20925534] doi:10.1056/NEJMoa1007964 CrossrefMedlineGoogle Scholar7. 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Lanas A, Aabakken L, Fonseca J, et al. Variability in the management of nonvariceal upper gastrointestinal bleeding in Europe: an observational study. Adv Ther. 2012;29:1026-36. [PMID: 23225523] doi:10.1007/s12325-012-0069-x CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: University Clinic Hospital, University of Zaragoza, CIBERehd, IIS Aragón, Zaragoza, Spain (A.L.)Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M19-2789.Corresponding Author: Angel Lanas, MD, Servicio de Aparato Digestivo, Hospital Clínico Universitario Lozano Blesa, c/San Juan Bosco 15, 50009 Zaragoza, Spain; e-mail, [email protected]es.This article was published at Annals.org on 22 October 2019. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoManagement of Nonvariceal Upper Gastrointestinal Bleeding: Guideline Recommendations From the International Consensus Group Alan N. Barkun , Majid Almadi , Ernst J. Kuipers , Loren Laine , Joseph Sung , Frances Tse , Grigorios I. Leontiadis , Neena S. Abraham , Xavier Calvet , Francis K.L. Chan , James Douketis , Robert Enns , Ian M. Gralnek , Vipul Jairath , Dennis Jensen , James Lau , Gregory Y.H. Lip , Romaric Loffroy , Fauze Maluf-Filho , Andrew C. Meltzer , Nageshwar Reddy , John R. Saltzman , John K. Marshall , and Marc Bardou Metrics Cited byEfficacy and Safety of Treatments for Patients With Portal Hypertension and Cirrhosis: A Systematic Review and Bayesian Network Meta-AnalysisA novel rationale for targeting FXI: Insights from the hemostatic microRNA targetome for emerging anticoagulant strategiesNon-Vitamin K Antagonist Oral Anticoagulants and the Gastrointestinal Bleeding Risk in Real-World Studies 3 December 2019Volume 171, Issue 11Page: 853-854KeywordsAnticoagulant therapyAnticoagulantsAntiplatelet therapyDrug therapyEndoscopyForecastingHemorrhageProton pump inhibitorsResuscitationStable coronary artery disease ePublished: 22 October 2019 Issue Published: 3 December 2019 Copyright & PermissionsCopyright © 2019 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...