THU0495 Indices of vertebral pain syndrome, physical performance and quality of life in older age women with vertebral fractures depending on their quantity and localization
Authors: N. Grygorieva, V. Povoronyuk, O. Rybina
Journal: Annals of the Rheumatic Diseases (2018)

<h3>Background</h3> Nowadays, vertebral fractures (VF) are one of the frequent and severe complications of systemic osteoporosis, which lead to severe spine pain, restriction of physical activity, increased disability and mortality, however, the data about their particularities depending on their quantity and localization are limited. The purpose was to study the indices of vertebral pain syndrome, physical performance, disability and quality of life in women of older age groups with VF depending on their number and localization. <h3>Objectives</h3> We examined 230 women aged 50–89 years old, which were divided into 2 groups: I – patients without any history of osteoporotic fractures (n=151), II – women with VF at thoracic and/or lumbar spine (n=79). Subsequently, the persons of the second group were divided into subgroups depending on the number (1 or 2 and more) and localization (thoracic, lumbar spine or combined) VF. <h3>Methods</h3> The presence and intensity of pain in the thoracic and lumbar spine were evaluated using the 11-component visual analogue scale (VAS), the level of physical performance was evaluated using static and dynamic functional tests (FT) (Thomayer, Schober tests, chest excursion, lateral trunk lean, 3-, 4-, 15-metre tests, "stand up from the chair", static balancing); disturbance of life was determined using Roland-Morris questionnaire, quality of life - EuroQol-5D questionnaire. <h3>Results</h3> It was demonstrated that the intensity of vertebral pain (pain at the time of investigation, the most common level of pain, pain in the best periods of the disease) is significantly worse in women with VF than corresponding parameters in persons without fractures. It was found that women with 2 and more VF have worse values of majority of measured FT (results of Schober test, lateral trunk lean, chest excursion, breath holding, hand grip strength, 15-metre test) in comparison with control group, while in women with 1 VF only results of Schober test and breath holding were significantly worse than same ones in control group. It was shown that for women with VF at the thoracic spine, results of breath holding and 15-metre tests were significantly worse compared with control, whereas in persons with VF at lumbar spine results of Schober index, lateral trunk lean, hand grip strength and test "stand up from the chair" were worse. In patients with combined VF most of the FT (lateral trunk lean, chest excursion, hand grip strength and 15-metre test) were significantly worse in comparison with control group. The Roland-Morris questionnaire score was significantly higher in women with 2 or more VF compared to controls, unlike the women with 1 VF. We did not found any differences in EQ-5D questionnaire score depending on the number and location of VF. <h3>Conclusions</h3> Indices of pain assessment and physical performance in women of older age groups have own peculiarities depending on the number and location of VF, which should be taken into account while assessing of physical abilities and developing of rehabilitation programs for people with VF. <h3>Acknowledgements</h3> We are grateful for the collaboration of the group of scientists of «Institute of Gerontology named after D. F. Chebotarev of NAMS Ukraine» (Kyiv, Ukraine) who performed clinical examination, pain assessment and physical performance. <h3>Disclosure of Interest</h3> None declared