Diagnosis and Treatment of Primary Aldosteronism
Authors: GianPaolo Rossi
Journal: Annals of Internal Medicine (1995)

Letters1 July 1995Diagnosis and Treatment of Primary AldosteronismGianPaolo Rossi, MD, Michele Gregianin, MD, and Mattco Chisura-Corona, MDGianPaolo Rossi, MDUniversity of Padua; 35126 Padua; ItalySearch for more papers by this author, Michele Gregianin, MDUniversity of Padua; 35126 Padua; ItalySearch for more papers by this author, and Mattco Chisura-Corona, MDUniversity of Padua; 35126 Padua; ItalySearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-123-1-199507010-00013 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:In their review of primary aldosteronism, Blumenfeld and colleagues [1] reported that a high proportion (almost 10%) of their 82 patients had adrenalectomy despite the presence of idiopathic hyperaldosteronism. However, medical treatment with aldosterone antagonists (not surgery) is deemed to be the treatment of choice for such conditions [2]. Blumenfeld and colleagues reported that three such patients (37.5%) were cured and one had improved after adrenalectomy but failed to provide any histologic data to corroborate the diagnosis of idiopathic hyperaldosteronism. Therefore, it remains possible that those patients, two of whom had lateralized aldosterone secretion, had a small ...References1. Blumenfeld JD, Sealey JE, Schlussel Y, Vaughan ED Jr, Sos TA, Atlas SA, et al. Diagnosis and treatment of primary hyperaldosteronism. Ann Intern Med. 1994; 121:877-85. Google Scholar2. Young WF Jr, Hogan MJ, Klee GG, Grant CS, van Heerden JA. Primary aldosteronism: diagnosis and treatment. Mayo Clin Proc. 1990; 65:96-110. Google Scholar3. Rossi GP, Ghiesura-Corona M, Soattin S, Tregnaghi A, Zanin L, Perale R, et al. Imaging of aldosterone secreting adenomas: a prospective comparison of computed tomography and magnetic resonance imaging in 27 patients with suspected primary aldosteronism. J Hum Hypertens. 1993; 7:357-63. Google Scholar4. Gordon RD, Gomez-Sanchez CE, Hamlet SM, Tunny TJ, Klemm SA. Angiotensin-responsive aldosterone-producing adenoma masquerades as idiopathic hyperaldosteronim (IHA: adrenal hyperplasia) or low-renin essential hypertension. J Hypertens. 1987; 5(Suppl 5):S103-6. Google Scholar5. Banks WA, Kastin AJ, Ruiz AE, Biglieri EG. Primary adrenal hyperplasia: a new subset of primary aldosteronism. J Clin Endocrinol Metab. 1984; 58:783-5. Google Scholar Author, Article, and Disclosure InformationAffiliations: University of Padua; 35126 Padua; Italy PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byHyperparathyroidism in patients with overt and mild primary aldosteronismAssessment of the Quantitative Value Usefulness of the Aldosterone-Renin Ratio (ARR) for Primary Aldosteronism (AQUARR) StudyPrimary aldosteronism and its various clinical scenariosPrimary Hyperaldosteronism and Other Forms of Mineralocorticoid HypertensionA Prospective Study of the Prevalence of Primary Aldosteronism in 1,125 Hypertensive PatientsPrimary aldosteronism: A needle in a haystack or a yellow cab on fifth avenue?Screening for primary aldosteronism with a logistic multivariate discriminant analysis * 1 July 1995Volume 123, Issue 1Page: 73-74KeywordsAdenomasAdrenalectomyAldosteroneComputed axial tomographyMagnetic resonance imagingRadionuclide imagingSurgeryVeins Issue Published: 1 July 1995 Copyright & PermissionsCopyright © 1995 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...