Binge-Eating Disorder in Adults
Authors: Denise E. Wilfley, Ellen E. Fitzsimmons-Craft, Dawn M. Eichen
Journal: Annals of Internal Medicine (2017)

Letters7 February 2017Binge-Eating Disorder in AdultsDenise E. Wilfley, PhD, Ellen E. Fitzsimmons-Craft, PhD, and Dawn M. Eichen, PhDDenise E. Wilfley, PhDFrom Washington University School of Medicine, St. Louis, Missouri., Ellen E. Fitzsimmons-Craft, PhDFrom Washington University School of Medicine, St. Louis, Missouri., and Dawn M. Eichen, PhDFrom Washington University School of Medicine, St. Louis, Missouri.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/L16-0622 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Brownley and colleagues' (1) meta-analysis of treatment for binge-eating disorder (BED) recommends therapist-led cognitive behavioral therapy (CBT), lisdexamfetamine, and second-generation antidepressants as the most well-supported options. However, several factors require consideration when interpreting these conclusions.First, attention to durability of effects is lacking. The meta-analysis provides no data on response to pharmacotherapy after medication has been stopped, and the active treatment periods have been very short (6 to 16 weeks). In contrast, large-scale randomized, controlled trials of CBT and interpersonal psychotherapy (IPT) funded by the National Institutes of Health have shown robust outcomes up to 2 years ...References1. Brownley KA, Berkman ND, Peat CM, Lohr KN, Cullen KE, Bann CM, et al. Binge-eating disorder in adults. A systematic review and meta-analysis. Ann Intern Med. 2016;165:409-20. [PMID: 27367316]. doi:10.7326/M15-2455 LinkGoogle Scholar2. Grilo CM, White MA, Masheb RM. DSM-IV psychiatric disorder comorbidity and its correlates in binge eating disorder. Int J Eat Disord. 2009;42:228-34. [PMID: 18951458] doi:10.1002/eat.20599 CrossrefMedlineGoogle Scholar3. Mitchell JE. Medical comorbidity and medical complications associated with binge-eating disorder. Int J Eat Disord. 2016;49:319-23. [PMID: 26311499] doi:10.1002/eat.22452 CrossrefMedlineGoogle Scholar4. Wilfley DE, Welch RR, Stein RI, Spurrell EB, Cohen LR, Saelens BE, et al. A randomized comparison of group cognitive-behavioral therapy and group interpersonal psychotherapy for the treatment of overweight individuals with binge-eating disorder. Arch Gen Psychiatry. 2002;59:713-21. [PMID: 12150647] CrossrefMedlineGoogle Scholar5. Wilson GT, Wilfley DE, Agras WS, Bryson SW. Psychological treatments of binge eating disorder. Arch Gen Psychiatry. 2010;67:94-101. [PMID: 20048227] doi:10.1001/archgenpsychiatry.2009.170 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Washington University School of Medicine, St. Louis, Missouri.Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L16-0622. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoBinge-Eating Disorder in Adults Kimberly A. Brownley , Nancy D. Berkman , Christine M. Peat , Kathleen N. Lohr , Katherine E. Cullen , Carla M. Bann , and Cynthia M. Bulik Binge-Eating Disorder in Adults Kimberly A. Brownley , Nancy D. Berkman , Christine M. Peat , Kathleen N. Lohr , and Cynthia M. Bulik Metrics Cited byA review on association and correlation of genetic variants with eating disorders and obesityBinge-Related Eating Disorders (Binge Eating Disorder and Bulimia Nervosa)Problems with Current Approaches to Treating Disorders of OvereatingEating Disorders on College Campuses in the United States: Current Insight on Screening, Prevention, and Treatment 7 February 2017Volume 166, Issue 3Page: 230-231KeywordsAntidepressantsCognitive behavior therapyDisclosureDrug therapyMetabolic syndromeObesitySleepSympathetic nervous system ePublished: 7 February 2017 Issue Published: 7 February 2017 Copyright & PermissionsCopyright © 2017 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...