Presence of Human Hepegivirus-1 in a Cohort of People Who Inject Drugs
Authors: Daniel Candotti, Xuelian Deng, Tingting Li, Syria Laperche, Virginie Sauvage
Journal: Annals of Internal Medicine (2018)

Letters16 January 2018Presence of Human Hepegivirus-1 in a Cohort of People Who Inject DrugsDaniel Candotti, PhD, Xuelian Deng, MsC, Tingting Li, PhD, Syria Laperche, MD, PhD, and Virginie Sauvage, PhDDaniel Candotti, PhDInstitut National de la Transfusion Sanguine, Paris, France (D.C., S.L., V.S.)Search for more papers by this author, Xuelian Deng, MsCDalian Blood Centre, Dalian, China (X.D.)Search for more papers by this author, Tingting Li, PhDSouthern Medical University, Guangzhou, China (T.L.)Search for more papers by this author, Syria Laperche, MD, PhDInstitut National de la Transfusion Sanguine, Paris, France (D.C., S.L., V.S.)Search for more papers by this author, and Virginie Sauvage, PhDInstitut National de la Transfusion Sanguine, Paris, France (D.C., S.L., V.S.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/L17-0525 SectionsSupplemental MaterialAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail This article has been corrected. The original version (PDF) is appended to this article as a Supplement.TO THE EDITOR:Kandathil and colleagues' study (1) showed a high prevalence (10.9%) of the novel RNA virus HHpgV-1 (also reported as human pegivirus-2 [HPgV-2]) in injection drug users, whereas the prevalence in HCV-infected U.S. blood donors was only approximately 1% (1–3). We tested 1317 plasma samples from randomly selected blood donors with HCV infection (n = 1173) and without HCV infection (n = 144) collected in France, China, and sub-Saharan Africa (Burkina Faso, Burundi, Cameroon, Niger, Madagascar, Mali, Mauritania, and the Democratic Republic of ...References1. Kandathil AJ, Breitwieser FP, Sachithanandham J, Robinson M, Mehta SH, Timp W, et al. Presence of human hepegivirus-1 in a cohort of people who inject drugs. Ann Intern Med. 2017;167:1-7. [PMID: 28586923]. doi:10.7326/M17-0085 LinkGoogle Scholar2. Kapoor A, Kumar A, Simmonds P, Bhuva N, Singh Chauhan L, Lee B, et al. Virome analysis of transfusion recipients reveals a novel human virus that shares genomic features with hepaciviruses and pegiviruses. MBio. 2015;6:e01466-15. [PMID: 26396247] doi:10.1128/mBio.01466-15 CrossrefMedlineGoogle Scholar3. Berg MG, Lee D, Coller K, Frankel M, Aronsohn A, Cheng K, et al. Discovery ofti novel human pegivirus in blood associated with hepatitis C virus co-infection. PLoS Pathog. 2015;11:e1005325. [PMID: 26658760] doi:10.1371/journal.ppat.1005325 CrossrefMedlineGoogle Scholar4. Bonsall D, Gregory WF, Ip CL, Donfield S, Iles J, Ansari MA, et al. Evaluation of viremia frequencies of a novel human pegivirus by using bioinformatic screening and PCR. Emerg Infect Dis. 2016;22:671-8. [PMID: 26982117] doi:10.3201/eid2204.151812 CrossrefMedlineGoogle Scholar5. Frankel M, Forberg K, Coller KE, Berg MG, Hackett J, Cloherty G, et al. Development of a high-throughput multiplexed real time RT-PCR assay for detection of human pegivirus 1 and 2. J Virol Methods. 2017;241:34-40. [PMID: 28012898] doi:10.1016/j.jviromet.2016.12.013 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Institut National de la Transfusion Sanguine, Paris, France (D.C., S.L., V.S.)Dalian Blood Centre, Dalian, China (X.D.)Southern Medical University, Guangzhou, China (T.L.)Disclosures: Authors have disclosed no conflicts of interest. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L17-0525. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoPresence of Human Hepegivirus-1 in a Cohort of People Who Inject Drugs Abraham J. Kandathil , Florian P. Breitwieser , Jaiprasath Sachithanandham , Matthew Robinson , Shruti H. Mehta , Winston Timp , Steven L. Salzberg , David L. Thomas , and Ashwin Balagopal Presence of Human Hepegivirus-1 in a Cohort of People Who Inject Drugs Shixing Tang and Haiying Wang Presence of Human Hepegivirus-1 in a Cohort of People Who Inject Drugs Abraham J. Kandathil , David L. Thomas , and Ashwin Balagopal Correction: Presence of Human Hepegivirus-1 in a Cohort of People Who Inject Drugs Metrics Cited byCorrection: Presence of Human Hepegivirus-1 in a Cohort of People Who Inject Drugs 16 January 2018Volume 168, Issue 2Page: 158KeywordsBlood donorsBlood plasmaDrugsInjecting drug usersPolymerase chain reactionRNAReverse transcriptase polymerase chain reactionRisk managementSafetyViral load ePublished: 16 January 2018 Issue Published: 16 January 2018 Copyright & PermissionsCopyright © 2018 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...