Transfusion-Transmitted Plasmodium falciparum in a Patient With Sickle Cell Hemoglobinopathy*
Authors: Salimah Valliani, Pradyumna Agasthi, Gloria Westney, Marilyn Foreman
Journal: Annals of Internal Medicine (2018)

Letters18 September 2018Transfusion-Transmitted Plasmodium falciparum in a Patient With Sickle Cell Hemoglobinopathy*Salimah Valliani, MD, Pradyumna Agasthi, MD, Gloria Westney, MD, MSCR, and Marilyn Foreman, MD, MSSalimah Valliani, MDMorehouse School of Medicine, Atlanta, Georgia (S.V., P.A., G.W., M.F.)Search for more papers by this author, Pradyumna Agasthi, MDMorehouse School of Medicine, Atlanta, Georgia (S.V., P.A., G.W., M.F.)Search for more papers by this author, Gloria Westney, MD, MSCRMorehouse School of Medicine, Atlanta, Georgia (S.V., P.A., G.W., M.F.)Search for more papers by this author, and Marilyn Foreman, MD, MSMorehouse School of Medicine, Atlanta, Georgia (S.V., P.A., G.W., M.F.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/L17-0303 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Background: Sickle cell disease is a genetic hemoglobinopathy that often presents as a vaso-occlusive crisis. Moyamoya disease, which is a complication of sickle cell disease, is a progressive, occlusive cerebrovascular disorder that affects the circle of Willis and the arteries that feed it (1).Objective: To describe a case of transfusion-transmitted Plasmodium falciparum infection resulting in multiorgan failure in a patient with sickle cell anemia.Case Report: An 18-year-old African American man with a history of essential hypertension, moyamoya disease, and homozygous sickle cell disease presented with fever, chills, and generalized body pain of 1 week's duration. He had been ...References1. Suzuki J, Takaku A. Cerebrovascular “moyamoya” disease. Disease showing abnormal net-like vessels in base of brain. Arch Neurol. 1969;20:288-99. [PMID: 5775283] CrossrefMedlineGoogle Scholar2. Centers for Disease Control and Prevention. Fast facts: malaria. 2015. Accessed at www.cdc.gov/malaria/about/facts.html on 14 April 2018. Google Scholar3. Mungai M, Tegtmeier G, Chamberland M, Parise M. Transfusion-transmitted malaria in the United States from 1963 through 1999. N Engl J Med. 2001;344:1973-8. [PMID: 11430326] CrossrefMedlineGoogle Scholar4. Guerrero IC, Weniger BG, Schultz MG. Transfusion malaria in the United States, 1972-1981. Ann Intern Med. 1983;99:221-6. [PMID: 6349456] LinkGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Morehouse School of Medicine, Atlanta, Georgia (S.V., P.A., G.W., M.F.)Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L17-0303.* Different aspects of the same patient's clinical course can be found in Maier CL, Gross PJ, Dean CL, Chonat S, Ip A, McLemore M, et al. Transfusion-transmitted malaria masquerading as sickle cell crisis with multisystem organ failure. Transfusion. 2018. [Epub ahead of print]. [PMID: 29524230] doi:10.1111/trf.14566. Valliani and colleagues were unaware of this report until after publication of their report. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoCorrection: Transfusion-Transmitted Plasmodium falciparum in a Patient With Sickle Cell Hemoglobinopathy Metrics Cited byCorrection: Transfusion-Transmitted Plasmodium falciparum in a Patient With Sickle Cell Hemoglobinopathy 18 September 2018Volume 169, Issue 6Page: 417-418KeywordsBloodDisclosureHemoglobinHemoglobinopathiesMalariaPlasmodium falciparumRed blood cellsSickle cell diseaseThoraxUrine ePublished: 8 May 2018 Issue Published: 18 September 2018 Copyright & PermissionsCopyright © 2018 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...