Transcatheter Aortic Valve Implantation Versus Surgical Aortic Valve Replacement
Authors: Xinlin Zhang, Biao Xu
Journal: Annals of Internal Medicine (2017)

Letters18 April 2017Transcatheter Aortic Valve Implantation Versus Surgical Aortic Valve ReplacementXinlin Zhang, MD and Biao Xu, MD, PhDXinlin Zhang, MDFrom Affiliated Drum Tower Hospital, Nanjing University School of Medicine, Nanjing, China.Search for more papers by this author and Biao Xu, MD, PhDFrom Affiliated Drum Tower Hospital, Nanjing University School of Medicine, Nanjing, China.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/L17-0106 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Gargiulo and colleagues' meta-analysis compares transcatheter aortic valve implantation (TAVI) with surgical aortic valve replacement (SAVR) in patients with severe aortic stenosis at low to intermediate and high risk (1). They conclude that early and midterm all-cause mortality were similar between TAVI and SAVR but that TAVI was associated with a statistically nonsignificant increased risk for long-term mortality. The authors' conclusion on long-term mortality was questionable because the overall result was driven mainly by data from observational studies, which caused significant heterogeneity and showed significant subgroup interaction between randomized trials and observational studies. Although all included observational ...References1. Gargiulo G, Sannino A, Capodanno D, Barbanti M, Buccheri S, Perrino C, et al. Transcatheter aortic valve implantation versus surgical aortic valve replacement: a systematic review and meta-analysis. Ann Intern Med. 2016;165:334-44. [PMID: 27272666]. doi:10.7326/M16-0060 LinkGoogle Scholar2. Kodali S, Williams MR, Doshi D, Hahn RT, Humphries KH, Nkomo VT, et al. Sex-specific differences at presentation and outcomes among patients undergoing transcatheter aortic valve replacement: a cohort study. Ann Intern Med. 2016;164:377-84. [PMID: 26903039]. doi:10.7326/M15-0121 LinkGoogle Scholar3. O'Connor SA, Morice MC, Gilard M, Leon MB, Webb JG, Dvir D, et al. Revisiting sex equality with transcatheter aortic valve replacement outcomes: a collaborative, patient-level meta-analysis of 11,310 patients. J Am Coll Cardiol. 2015;66:221-8. [PMID: 26184614] doi:10.1016/j.jacc.2015.05.024 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Affiliated Drum Tower Hospital, Nanjing University School of Medicine, Nanjing, China.Disclosures: Authors have disclosed no conflicts of interest. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L17-0106. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoTranscatheter Aortic Valve Implantation Versus Surgical Aortic Valve Replacement Giuseppe Gargiulo , Anna Sannino , Davide Capodanno , Marco Barbanti , Sergio Buccheri , Cinzia Perrino , Piera Capranzano , Ciro Indolfi , Bruno Trimarco , Corrado Tamburino , and Giovanni Esposito Transcatheter Aortic Valve Implantation Versus Surgical Aortic Valve Replacement Marat Fudim , Gerald S. Bloomfield , and Zainab Samad Transcatheter Aortic Valve Implantation Versus Surgical Aortic Valve Replacement Giuseppe Gargiulo , Davide Capodanno , Corrado Tamburino , Bruno Trimarco , and Giovanni Esposito Metrics 18 April 2017Volume 166, Issue 8Page: 605KeywordsAortic valve replacementCohort studiesConflicts of interestDisclosureMortalityNetwork analysisObservational studiesRandomized trialsStenosis ePublished: 18 April 2017 Issue Published: 18 April 2017 Copyright & PermissionsCopyright © 2017 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...