E-Cigarettes and Toxin Exposure
Authors: Henri-Jean Aubin, Pascal Guénel, Marie-Christine Boutron-Ruault, Mireille Matrat, Amandine Luquiens, Patrick Dupont
Journal: Annals of Internal Medicine (2017)

Letters3 October 2017E-Cigarettes and Toxin ExposureHenri-Jean Aubin, MD, PhD, Pascal Guénel, MD, PhD, Marie-Christine Boutron-Ruault, MD, PhD, Mireille Matrat, MD, Amandine Luquiens, MD, PhD, and Patrick Dupont, MDHenri-Jean Aubin, MD, PhDFrom CESP, Université Paris-Sud, Université de Versailles-Saint-Quentin-en-Yvelines, Institut National de la Santé et Recherche Médicale, Université Paris-Saclay, Institut Gustave Roussy, and Assistance Publique–Hôpitaux de Paris, Hôpitaux Universitaires Paris-Sud, Villejuif, France.Search for more papers by this author, Pascal Guénel, MD, PhDFrom CESP, Université Paris-Sud, Université de Versailles-Saint-Quentin-en-Yvelines, Institut National de la Santé et Recherche Médicale, Université Paris-Saclay, Institut Gustave Roussy, and Assistance Publique–Hôpitaux de Paris, Hôpitaux Universitaires Paris-Sud, Villejuif, France.Search for more papers by this author, Marie-Christine Boutron-Ruault, MD, PhDFrom CESP, Université Paris-Sud, Université de Versailles-Saint-Quentin-en-Yvelines, Institut National de la Santé et Recherche Médicale, Université Paris-Saclay, Institut Gustave Roussy, and Assistance Publique–Hôpitaux de Paris, Hôpitaux Universitaires Paris-Sud, Villejuif, France.Search for more papers by this author, Mireille Matrat, MDFrom CESP, Université Paris-Sud, Université de Versailles-Saint-Quentin-en-Yvelines, Institut National de la Santé et Recherche Médicale, Université Paris-Saclay, Institut Gustave Roussy, and Assistance Publique–Hôpitaux de Paris, Hôpitaux Universitaires Paris-Sud, Villejuif, France.Search for more papers by this author, Amandine Luquiens, MD, PhDFrom CESP, Université Paris-Sud, Université de Versailles-Saint-Quentin-en-Yvelines, Institut National de la Santé et Recherche Médicale, Université Paris-Saclay, Institut Gustave Roussy, and Assistance Publique–Hôpitaux de Paris, Hôpitaux Universitaires Paris-Sud, Villejuif, France.Search for more papers by this author, and Patrick Dupont, MDFrom CESP, Université Paris-Sud, Université de Versailles-Saint-Quentin-en-Yvelines, Institut National de la Santé et Recherche Médicale, Université Paris-Saclay, Institut Gustave Roussy, and Assistance Publique–Hôpitaux de Paris, Hôpitaux Universitaires Paris-Sud, Villejuif, France.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/L17-0314 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Shahab and colleagues' (1) small, cross-sectional study found that long-term use of nicotine replacement therapy (NRT) and e-cigarettes is associated with lower levels of carcinogens and toxins than cigarette smoking. They conclude that these lower levels confirm the “known low risk for complications from long-term NRT use” and support the assertion that e-cigarettes may be less harmful than smoking. Although the inference that reducing the intensity of carcinogen exposure may reduce the risk for cancer may seem obvious at first, we believe that duration is more strongly associated with this risk than intensity of exposure.Regarding risk ...References1. Shahab L, Goniewicz ML, Blount BC, Brown J, McNeill A, Alwis KU, et al. Nicotine, carcinogen, and toxin exposure in long-term e-cigarette and nicotine replacement therapy users. A cross-sectional study. Ann Intern Med. 2017;166:390-400. [PMID: 28166548]. doi:10.7326/M16-1107 LinkGoogle Scholar2. Peto J. That the effects of smoking should be measured in pack-years: misconceptions 4 [Editorial]. Br J Cancer. 2012;107:406-7. [PMID: 22828655] doi:10.1038/bjc.2012.97 CrossrefMedlineGoogle Scholar3. Office of the Surgeon General (US); Office on Smoking and Health (US).. The Health Consequences of Smoking: A Report of the Surgeon General. Atlanta: Centers for Disease Control and Prevention; 2004. Google Scholar4. Murray RP, Connett JE, Zapawa LM. Does nicotine replacement therapy cause cancer? Evidence from the Lung Health Study. Nicotine Tob Res. 2009;11:1076-82. [PMID: 19571249] doi:10.1093/ntr/ntp104 CrossrefMedlineGoogle Scholar5. Dupont P, Benyamina A, Aubin HJ. [Safety of long-term nicotine use: an ongoing debate]. Rev Mal Respir. 2016;33:892-8. [PMID: 27242286] doi:10.1016/j.rmr.2016.05.002 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From CESP, Université Paris-Sud, Université de Versailles-Saint-Quentin-en-Yvelines, Institut National de la Santé et Recherche Médicale, Université Paris-Saclay, Institut Gustave Roussy, and Assistance Publique–Hôpitaux de Paris, Hôpitaux Universitaires Paris-Sud, Villejuif, France.Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L17-0314. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoNicotine, Carcinogen, and Toxin Exposure in Long-Term E-Cigarette and Nicotine Replacement Therapy Users Lion Shahab , Maciej L. Goniewicz , Benjamin C. Blount , Jamie Brown , Ann McNeill , K. Udeni Alwis , June Feng , Lanqing Wang , and Robert West E-Cigarettes and Toxin Exposure Lion Shahab , Maciej L. Goniewicz , Benjamin C. Blount , Jamie Brown , and Robert West Metrics Cited byExposition des vapoteurs au formaldéhyde et à l’acroléine : revue systématique 3 October 2017Volume 167, Issue 7Page: 524-525KeywordsCarcinogensDisclosureLung and intrathoracic tumorsNicotineNicotine replacement therapySafetySafety studiesSurgeonsToxins ePublished: 3 October 2017 Issue Published: 3 October 2017 Copyright & PermissionsCopyright © 2017 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...