Comparison of Five Major Guidelines for Statin Use in Primary Prevention
Authors: Philippe Giral
Journal: Annals of Internal Medicine (2018)

Letters3 July 2018Comparison of Five Major Guidelines for Statin Use in Primary PreventionPhilippe Giral, MDPhilippe Giral, MDSorbonne Université, Pitié-Salpétrière Hospital, Assistance Publique–Hôpitaux de Paris, Paris, France (P.G.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/L18-0180 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Mortensen and Nordestgaard's (1) well-done study compares the European Systematic Coronary Risk Evaluation (SCORE) prediction model with 4 other Anglo-Saxon models for prevention of ASCVD. The problem is that the SCORE model aims to reduce deaths and not cardiovascular events as a whole. It differs from other risk estimation systems because it estimates the 10-year risk for a first fatal atherosclerotic event, be it heart attack; stroke; or other occlusive arterial disease, including sudden cardiac death (2). The risk for total nonfatal events would obviously be higher, and the difference must be quantified. The risk for total ...References1. Mortensen MB, Nordestgaard BG. Comparison of five major guidelines for statin use in primary prevention in a contemporary general population. Ann Intern Med. 2018;168:85-92. [PMID: 29297004]. doi:10.7326/M17-0681 LinkGoogle Scholar2. Piepoli MF, Hoes AW, Agewall S, Albus C, Brotons C, Catapano AL, et al; ESC Scientific Document Group. 2016 European guidelines on cardiovascular disease prevention in clinical practice: the Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of 10 societies and by invited experts) developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR). Eur Heart J. 2016;37:2315-81. [PMID: 27222591] doi:10.1093/eurheartj/ehw106 CrossrefMedlineGoogle Scholar3. Reiner Z, Catapano AL, De Backer G, Graham I, Taskinen MR, Wiklund O, et al; European Association for Cardiovascular Prevention & Rehabilitation. ESC/EAS guidelines for the management of dyslipidaemias: the Task Force for the Management of Dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS). Eur Heart J. 2011;32:1769-818. [PMID: 21712404] doi:10.1093/eurheartj/ehr158 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Sorbonne Université, Pitié-Salpétrière Hospital, Assistance Publique–Hôpitaux de Paris, Paris, France (P.G.)Disclosures: The author has disclosed no conflicts of interest. The form can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L18-0180. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoComparison of Five Major Guidelines for Statin Use in Primary Prevention in a Contemporary General Population Martin Bødtker Mortensen and Børge Grønne Nordestgaard Comparison of Five Major Guidelines for Statin Use in Primary Prevention Adrienne J. Lindblad and Christina Korownyk Comparison of Five Major Guidelines for Statin Use in Primary Prevention Martin Bødtker Mortensen and Børge Nordestgaard Metrics 3 July 2018Volume 169, Issue 1Page: 67KeywordsAtherosclerotic cardiovascular diseaseConflicts of interestDisclosureElderlyHeart diseasesMortalityMyocardial infarctionStatinsStrokeSudden cardiac death ePublished: 3 July 2018 Issue Published: 3 July 2018 Copyright & PermissionsCopyright © 2018 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...