tbuckley/cabot-search huggingface dataset:
Physical activity and lifestyle in women with metastatic breast cancer: The ABLE study
Authors: B. Fervers, L. Delrieu, O. Pérol, O. Febvey-Combes, A. Dufresne, T. Bachelot, P. Heudel, O. Tredan, M. Touillaud, V. Pialoux
Journal: Annals of Oncology (2018)
SET overexpression promotes colorectal cancer progression and determines poor outcome in patients with localized disease
Authors: B. Torrejón, M. Pedregal Trujillo, A. Santos, J. Rubio, M. Luque, M. Sanz, C. Carames, S. Zazo, J. Madoz-Gurpide, F. Rojo, J. Garcia Foncillas, C. Ion
Journal: Annals of Oncology (2018)
RET rearrangements may arise following anti-EGFR therapy in advanced colorectal cancer
Authors: T.A. Rich, K. Clifton, A. Grothey, A. Hendifar, D.H. Henry, Y. Kagawa, Y. Nakamura, W. Okamoto, B.R. Tan, G. Sherrill, T. Yoshino, V.M. Raymond, Y. Shiotsu, R.B. Lanman, V. Morris
Journal: Annals of Oncology (2018)
Impact of the EML4-ALK variant on the efficacy of alectinib (ALC) in untreated ALK+ advanced NSCLC (aNSCLC) in the global phase III ALEX study
Authors: R. Dziadziuszko, T.S. Mok, D.R. Camidge, A.T. Shaw, J. Noe, M. Nowicka, T. Liu, E. Mitry, S. Peters
Journal: Annals of Oncology (2018)
The role of bevacizumab plus front-line chemotherapy in patients with malignant ascites of ovarian cancer
Authors: M. Nikolaou, N. Ziras, I. Athanasiadis, A. Ardavanis, M. Vaslamatzis, N. Kentepozidis, P. Makrantonakis, A.N. Christopoulou, V. Michalaki, A. Polizos, C. Emmanouilidis, V. Georgoulias
Journal: Annals of Oncology (2018)
Secular trends in mortality and causes of death among children and adolescents aged 1–19 years in China from 1953 to 2016: a national and subnational variations systematic analysis
Authors: Yanhui Dong, Peijin Hu, Yi Song, Bin Dong, Zhiyong Zou, Zhenghe Wang, Rongbin Xu, Dongmei Luo, Disi Gao, Bo Wen, Yinghua Ma, Jun Ma, Xiaobo Tian, Xiaona Huang, George C Patton
Journal: The Lancet (2018)
P1.01-98 A Phase IIIb Trial of Afatinib in EGFRm+ NSCLC: Analyses of Outcomes in Patients with Brain Metastases or Dose Reductions
Authors: Y. Wu, H. Tu, J. Feng, M. Shi, J. Zhao, Y. Wang, J. Chang, J. Wang, Y. Cheng, J. Zhu, E. Tan, K. Li, Y. Zhang, V. Lee, C. Yang, W. Su, D.C. Lam, B. Srinivasa, S. Rajappa, C. Ho, K.C. Lam, Y. Hu, S.A. Bondarde, X. Liu, D.C. Huang, Y. Wang, K. Pang, C. Zhou
Journal: Journal of Thoracic Oncology (2018)
P1.17-11 Pattern and Survival Impact of Neoadjuvant Treatment of Non-Small Cell Lung Cancer (NSCLC) in a Prospective Lung Resection Cohort
Authors: M. Ray, M. Smeltzer, N. Faris, Y. Lee, C. Fehnel, C. Houston-Harris, O. Akinbobola, P. Ojeabulu, E. Owen, R. Eubanks, H. Dox, D. Talton, G. Valaulikar, H. Wiggins, B. Wolf, P. Levy, E. Robbins, R. Osarogiagbon
Journal: Journal of Thoracic Oncology (2018)
P3.01-51 Outcomes with Systemic Chemotherapy in Advanced NSCLC Patients with Performance Status 2 and Above and without Driver Mutation
Authors: H. Kancharla, P.S. Malik, S. Khurana, N. Gundu, A. Yadav, D. Jain, S. Pathy, S. Kumar
Journal: Journal of Thoracic Oncology (2018)
Phase II trial of neoadjuvant therapy using apatinib plus SOX regimen in locally advanced gastric cancer: Updated results
Authors: Y. Zheng, X. Yang, H. Shi, Z. Yang, C. Yan, Z. Ni, M. Li, B.K. Sah, W. Liu, W. Xu, X. Yao, Z. Zhu, M. Yan, Z. Zhu, C. Li
Journal: Annals of Oncology (2018)
Evaluation of the efficacy and safety of everolimus as a first-line treatment in newly diagnosed patients with advanced gastroenteropancreatic neuroendocrine tumors
Authors: A. Koumarianou, D.G. Pectasides, K. Manousou, D. Dionysopoulos, G.A. Kaltsas, D. Kolomodi, C. Poulios, M. Skondra, E. Samantas, G. Pentheroudakis, G. Fountzilas
Journal: Annals of Oncology (2018)
Final results of RENO study: Randomized phase II of oral vinorelbine or etoposide with cisplatin &amp; chemo-radiation in stage III NSCLC - SLCG 10/02
Authors: M. Provencio Pulla, R. de las Peñas, N. Martinez Banaclocha, R. MarsÉ Fabregat, A. Insa Molla, T. Moran, M.A. Sala Gonzalez, B. Massuti Sureda, P. Mut Sanchis, A.L. Ortega Granados, J.M. Jurado, J. Gomez Codina, A. Artal-Cortes, F. Vazquez, V. Gutierrez Calderon, P. Diz Tain, N. Vinolas Segarra, I. Maestu Maiques, C. Camps, M.D. Isla Casado
Journal: Annals of Oncology (2018)
P1.09-40 Metastatic Endometrial Sarcoma Presenting as a Spontaneous Pneumothorax and Masquerading as a Pulmonary Blastoma
Authors: G. Suero-Abreu, R. Wooley, J. Wang, N. Duma, M. Gonzalez Velez, A. Perez, A. Douglas, M. Gutierrez, K. Guevarra
Journal: Journal of Thoracic Oncology (2018)
P1.09-09 Evaluation of a Novel ROS1 Immunohistochemistry Clone (SP384) for the Identification of ROS1 Rearrangements in NSCLC Patients
Authors: E. Conde, S. Hernandez, R. Martinez, J. De Castro, A. Collazo-Lorduy, B. Jimenez, A. Muriel, J.L. Mate, T. Morán, I. Aranda, B. Massuti, F. Rojo, M. Domine, I. Sansano, F. Garcia, E. Felip, N. Mancheño, O. Juan, J. Sanz, J.L. Gonzalez-Larriba, L. Atienza-Cuevas, E. Arriola-Arellano, I. Abdulkader, J. Garcia, C. Camacho, D. Rodríguez-Abreu, C. Teixido, N. Reguart, A. Gonzalez-Piñeiro, M. Lazaro-Quintela, M.D. Lozano, A. Gurpide, J. Gomez-Roman, M. Lopez-Brea, L. Pijuan, M. Salido, E. Arriola, A. Company, A. Insa, I. Esteban, M. Saiz, E. Azkona, R. Alvarez, A. Artal, A.B. Enguita, A. Benito, L. Paz-Ares, P. Garrido, F. Lopez-Rios
Journal: Journal of Thoracic Oncology (2018)
OA12.07 Clinical Activity of LOXO-292, a Highly Selective RET Inhibitor, in Patients with RET Fusion+ Non-Small Cell Lung Cancer
Authors: G. Oxnard, V. Subbiah, K. Park, T. Bauer, L. Wirth, V. Velcheti, M. Shah, B. Besse, V. Boni, K. Reckamp, H. Loong, L. Bazhenova, B. Solomon, D. Tan, J. Patel, M. Johnson, A. Gazzah, T. Mok, S. Smith, B. Tuch, K. Ebata, E. Zhu, M. Nguyen, X. Huang, S. Cruickshank, S. Rothenberg, A. Drilon
Journal: Journal of Thoracic Oncology (2018)
ELOVL4: Very long-chain fatty acids serve an eclectic role in mammalian health and function
Authors: Blake R. Hopiavuori, Robert E. Anderson, Martin-Paul Agbaga
Journal: Progress in Retinal and Eye Research (2018)

ELOngation of Very Long chain fatty acids-4 (ELOVL4) is an elongase responsible for the biosynthesis of very long chain (VLC, ≥C28) saturated (VLC-SFA) and polyunsaturated (VLC-PUFA) fatty acids in brain, retina, skin, Meibomian glands, and testes. Fascinatingly, different mutations in this gene have been reported to cause vastly different phenotypes in humans. Heterozygous inheritance of seven different mutations in the coding sequence and 5' untranslated region of ELOVL4 causes autosomal dominant Stargardt-like macular dystrophy (STGD3), while homozygous inheritance of three more mutant variants causes severe seizures with ichthyosis, hypertonia, and even death. Some recent studies have described heterozygous inheritance in yet another three mutant ELOVL4 variants, two that cause spinocerebellar ataxia-34 (SCA34) with erythrokeratodermia (EKV) and one that causes SCA34 without EKV. We identified the specific enzymatic reactions catalyzed by ELOVL4 and, using a variety of genetically engineered mouse models, have actively searched for the mechanisms by which ELOVL4 impacts neural function and health. In this review, we critically compare and contrast the various animal model and case studies involving ELOVL4 deficiency via either mutation or deletion, and the resulting consequences on neuronal health and function in both the retina and central nervous system.
MA16.06 EGFR Clonality and Tumor Mutation Burden (TMB) by Circulating Tumor DNA (ctDNA) Sequencing in Advanced Non-Small Cell Lung Cancer (NSCLC)
Authors: X. Ai, Y. Lin, J. Zhang, C. Xie, A. Liu, X. Hu, Q. Zhao, Y. Zang, C. Rao, X. Hu, L. Chang, Q. Li, Y. Guan, R. Chen, X. Yi, S. Lu
Journal: Journal of Thoracic Oncology (2018)
Benefits of physical activity and sport integrated into the care pathway of oncology patient
Authors: L. Vanlemmens, H. Mocaer, T. Ginsbourger, J.M. Descotes, N. Masselin, H. Deroubaix, C. Fabre, J. Devriendt, T. Bouillet, E. Lartigau
Journal: Annals of Oncology (2018)
Symptomatic skeletal event (SSE) dynamics in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC) treated with radium-223 (Ra-223): An interim review of a prospective, non-interventional study (PARABO)
Authors: T. Poeppel, S. Eschmann, A. Werner, I. Selkinski, M.-O. Möllers, T. Neußer, A. Benson, J. Kalinovsky, H. Palmedo
Journal: Annals of Oncology (2018)
P1.13-08 Distribution, Differences in Clinical Characteristics and Resistance Mechanism of ALK Variants in Chinese Lung Cancer Patients
Authors: J. Zhao, Q. Li, G. Lin, X. Dong, L. Liu, L. Chen, J. Chen, Y. He, X. Ai, R. Guo, W. Wang, C. Xu, R. Chen, Y. Xin, X. Xia
Journal: Journal of Thoracic Oncology (2018)
Phase Ib/II, open label, multicenter, study of the combination of SD-101 and pembrolizumab in patients with advanced melanoma who are naïve to anti-PD-1 therapy
Authors: G.V. Long, M. Milhem, A. Amin, C.J. Hoimes, T. Medina, R.M. Conry, C. Lao, G. Daniels, S. Reddy, I. Mehmi, R.H.I. Andtbacka, M. Barve, M. Shaheen, T. Tueting, M. Chisamore, B. Xing, A. Candia, E. Gamelin, R. Janssen, A. Ribas
Journal: Annals of Oncology (2018)
Does the minimal axillary approach lead to loss of prognostic factors in breast cancer?
Authors: R.A. de Araujo, C.P. Nascimento, C.L.P. Da Cunha, E.D.C. Marinho, E.R.T. Mosca, F.A.C. Da Luz, P.F.R. Delfino, R.M. Antonioli, T.R. Mendes, M.J.B. Silva
Journal: Annals of Oncology (2018)
Spatial and Temporal Organization of the Individual Human Cerebellum
Authors: Scott Marek, Joshua S. Siegel, Evan M. Gordon, Ryan V. Raut, Caterina Gratton, Dillan J. Newbold, Mario Ortega, Timothy O. Laumann, Babatunde Adeyemo, Derek B. Miller, Annie Zheng, Katherine C. Lopez, Jeffrey J. Berg, Rebecca S. Coalson, Annie L. Nguyen, Donna Dierker, Andrew N. Van, Catherine R. Hoyt, Kathleen B. McDermott, Scott A. Norris, Joshua S. Shimony, Abraham Z. Snyder, Steven M. Nelson, Deanna M. Barch, Bradley L. Schlaggar, Marcus E. Raichle, Steven E. Petersen, Deanna J. Greene, Nico U.F. Dosenbach
Journal: Neuron (2018)
The difference of risk factor for gastric cancer surgery between elderly and non-elderly patients
Authors: T. Hayashi, T. Oshima, K. Hara, Y. Shimoda, M. Nakazono, S. Nagasawa, Y. Kumazu, T. Yamada, Y. Rino, M. Masuda, T. Ogata, T. Yoshikawa
Journal: Annals of Oncology (2018)
RCAS1 protein is expressed in multiple normal tissues and localizes to the endoplasmic reticulum-Golgi apparatus.
Authors: Ali Sadra, Langxing Pan, Ralph Yamamoto
Journal: Cancer Research (2004)

3296   Previous reports on RCAS1 (also known as EBAG9) have shown expression and upregulation in multiple human cancers. A number of these reports have indicated a positive correlation with the level of RCAS1 expression on the tumor cells and their clinical stage. In this work, we show that RCAS1 is also expressed in multiple normal human tissues. These include spleen, lung, kidney, testis, stomach, pancreas and liver at levels seen similar to those of the RCAS1 positive cancers. Expression of RCAS1 is almost all confined to the inside of the cell from the staining pattern of intact and permeabilized cells. Furthermore, there is no increased apoptosis of infiltrating lymphocytes in RCAS1-positive mass of tumor cells as measured by TUNEL staining. The reported increase of soluble RCAS1 (in the form of RCAS1-GST) binding to activated T lymphocytes is only in the order of 5 to 10 percent over the level of resting cells and the same lymphocyte population seems to express its own endogenous RCAS1. The role of RCAS1 in cancer and normal cells merits a closer examination.
P3.08-02 Oligometastatic Non Small Cell Lung Cancer Patients Treated with Stereotactic Body Radiotherapy (SBRT), a Single Institution Experience
Authors: D. Franceschini, F. De Rose, G. Radicioni, E. Toska, L. Faraci, G. Carta, M. Scorsetti
Journal: Journal of Thoracic Oncology (2018)
Abstract 15933: CD34+ Cell Transplantation Improves Right Ventricular Function in Patients With Nonischemic Dilated Cardiomyopathy
Authors: Sabina Frljak, Martina Jaklic, Gregor Poglajen, Gregor Zemljic, Andraz Cerar, Joseph C Wu, Bojan Vrtovec
Journal: Circulation (2017)

Introduction: Preclinical data suggest that cell therapy may improve right ventricular (RV) function in heart failure. Hypothesis: We investigated the effects of CD34+ cell therapy on RV function i...
Are treatment recommendations provided by cognitive computing supported by real world data (Watson for Oncology with Cota RWE) concordant with expert opinions?
Authors: D.M. Atieh Graham, D.M. McNamara, S.E. Waintraub, S.L. Goldberg, A.D. Norden, J. Hervey, A.L. Pecora, C. Landstrom, J.L. Snowdon, P.M. Francis, N. Jungbluth, C.K. Wang, L. Latts
Journal: Annals of Oncology (2018)
Weight loss, physical and psychological patient reported outcomes (PROs) among obese patients (pts) with early breast cancer (BC)
Authors: A. Di Meglio, M. El-Mouhebb, S. Michiels, L. Jones, E. Martin, M. Matias, A.E. Lohmann Palhares, F. Joly, L. Vanlemmens, S. Everhard, A.L. Martin, J. Lemonnier, P. Arveux, P.H. Cottu, C. Coutant, L. Del Mastro, A.H. Partridge, F. André, J.A. Ligibel, I. Vaz-Luis
Journal: Annals of Oncology (2018)
P1.01-69 Validation of the Lung Immune Prognostic Index (LIPI): Useful to Identify Resistance to PD-1 Checkpoint Inhibitors in Pretreated Lung Cancer
Authors: X. Mielgo-Rubio, M. Sereno Moyano, M. Sotelo-Lezama, R. Lopez Castro, J. Rubio-Martínez, A. Velastegui, C. Olier-Garate, S. Falagan, I. Gómez-Barreda, A. Riquelme, A. Cardeña-Gutiérrez, J. Moreno Rubio, C. López, C. Bueno, J. Silva-Ruiz, E. Zhan Zhou, L. Chara
Journal: Journal of Thoracic Oncology (2018)
P1.13-11 PRO-CTCAE Toxicities in Advanced NSCLC Patients with EGFR Mutations: A Real World Assessment
Authors: K. Hueniken, M. Hurry, S. Jiang, C. Labbe, M.C. Brown, L. Eng, H. Naik, M. Liang, D. Patel, P. Bradbury, N. Leighl, F. Shepherd, W. Xu, G. O'Kane, R. Walton, G. Liu
Journal: Journal of Thoracic Oncology (2018)
CYP11A1 inhibition as a therapeutic approach for the treatment of castration resistant prostate cancer
Authors: R. Oksala, K. Räsänen, M. Karimaa, R. Riikonen, M. Ramela, P. Vehmaan-Kreula, O. Simola, P. Rummakko, G. Wohlfahrt, M. Mustonen
Journal: Annals of Oncology (2018)
Impact of early steroids use on clinical outcomes of patients with advanced NSCLC treated with immune checkpoint inhibitors
Authors: G. Fucà, M. Poggi, G. Galli, M. Imbimbo, G. Lo Russo, D. Signorelli, M. Vitali, M. Ganzinelli, N. Zilembo, F. de Braud, M.C. Garassino, C. Proto
Journal: Annals of Oncology (2018)
Baseline prevalence of cardiovascular disease (CVD) risk factors in women with breast cancer
Authors: N. Bhoo-Pathy, S. Subramaniam, H. Zaharah, Y.C. Kong, N.A. Taib, A. Deniel, K.-H. Chee, R.S. Bustamam, M.-H. See, A. Fong, C.H. Yip
Journal: Annals of Oncology (2018)
Impact of HIV-1 CRF55_01B infection on CD4 counts and viral load in men who have sex with men naive to antiretroviral treatment
Authors: Lan Wei, Xing Lu, Hao Li, Chenli Zheng, Guilian Li, Zhengrong Yang, Lin Chen, Jinquan Cheng, Hui Wang, Jin Zhao
Journal: The Lancet (2018)
MA16.02 Prospective Clinical Validation of the InVisionFirst™ ctDNA Assay for Molecular Profiling of Patients with Advanced NSCLC
Authors: R. Govindan, M. Pritchett, D.R. Camidge, M. Patel, J. Khatri, S. Boniol, E.K. Friedman, A. Khomani, S. Dalia, K. Baker-Neblett, V. Plagnol, K. Howarth, N. Rosenfeld, C. Morris
Journal: Journal of Thoracic Oncology (2018)
MA17.02 Early Accrual to a Precision Lung Cancer Survivorship Intervention: The Kentucky LEADS Collaborative Lung Cancer Survivorship Care Program
Authors: J. Studts, J. Burris, M. Andrykowski, T. Schapmire, B. Head, M. Rigney, A. Criswell, S. Arnold, A. Yates, C. Blair, A. Christian
Journal: Journal of Thoracic Oncology (2018)
Microsatellite instability-high (MSI-H) colorectal cancers with elevated microsatellite alterations at selected tetranucleotide repeats (EMAST) signature represent a target population for immune checkpoint and DNA damaging therapies
Authors: K.T. Tan, P.-N. Yu, S.-J. Chen, Y.-T. Liu, S.-C. Chang, M.-H. Chen
Journal: Annals of Oncology (2018)
MA26.03 Activity of Osimertinib and the Selective RET Inhibitor BLU-667 in an EGFR-Mutant Patient with Acquired RET Rearrangement
Authors: Z. Piotrowska, H. Isozaki, J. Lennerz, S. Digumarthy, J. Gainor, N. Marcoux, M. Banwait, D. Dias-Santagata, A.J. Iafrate, M. Mino-Kenudson, R. Nagy, R. Lanman, E. Evans, C. Clifford, B. Wolf, A. Hata, L. Sequist
Journal: Journal of Thoracic Oncology (2018)
Diagnosis of invasion depth in resectable advanced gastric cancer for neoadjuvant chemotherapy: An exploratory analysis of JCOG1302A
Authors: Y. Sato, J. Mizusawa, K. Nakamura, T. Fukagawa, H. Katai, S. Haruta, M. Yamada, M. Takagi, S. Tamura, T. Yoshimura, T. Inada, N. Hirabayashi, I. Wada, Y. Kodera, M. Tokunaga, T. Yoshikawa, N. Boku, T. Sano, M. Sasako, M. Terashima
Journal: Annals of Oncology (2018)
P3.01-80 Retrospective Analysis of the Impact of EGFR T790M Mutation Detection by Re-Biopsy in Patients with NSCLC Harboring EGFR Mutations.
Authors: N. Okura, T. Yamada, A. Yoshimura, T. Takeda, Y. Kubota, S. Shiotsu, O. Hiranuma, J. Uchino, K. Takayama
Journal: Journal of Thoracic Oncology (2018)
Adiponectin homolog novel osmotin protects obesity/diabetes-induced NAFLD by upregulating AdipoRs/PPARα signaling in ob/ob and db/db transgenic mouse models
Authors: Ashfaq Ahmad, Tahir Ali, Min Woo Kim, Amjad Khan, Myeung Hoon Jo, Shafiq Ur Rehman, Muhammad Sohail Khan, Noman Bin Abid, Mehtab Khan, Rahat Ullah, Min Gi Jo, Myeong Ok Kim
Journal: Metabolism (2018)
P1.17-15 Perioperative Prognostic Nutrition Index for Induction Chemoradiotherapy Followed by Surgery in Locally Advanced Non-Small Lung Cancers
Authors: J. Soh, S. Miyauchi, K. Araki, A. Miura, Y. Takahashi, E. Kurihara, Y. Ogoshi, K. Shien, H. Yamamoto, S. Sugimoto, M. Yamane, K. Kiura, S. Kanazawa, S. Toyooka
Journal: Journal of Thoracic Oncology (2018)
P1.01-49 irAE, Possible Predictive Markers for Immune Checkpoint Inhibitors
Authors: K. Komiya, T. Nakamura, H. Hirakawa, S. Ogusu, C. Nakashima, K. Takahashi, S. Kimura, N. Sueoka-Aragane
Journal: Journal of Thoracic Oncology (2018)
Updated relapse-free survival (RFS) and biomarker analysis in the COMBI-AD trial of adjuvant dabrafenib + trametinib (D + T) in patients (pts) with resected BRAF V600–mutant stage III melanoma
Authors: G.V. Long, A. Hauschild, M. Santinami, V.G. Atkinson, M. Mandala, V. Chiarion-Sileni, J. Larkin, C. Robert, D. Schadendorf, K. Dasgupta, M. Shilkrut, J. Garrett, J.C. Brase, R. Kefford, J.M. Kirkwood, R. Dummer
Journal: Annals of Oncology (2018)
Abstract 20577: Combination of Global Longitudinal Strain and Sympathetic Nervous Dysfunction Predicts Cardiac Events in Patients With Non-Ischemic Dilated Cardiomyopathy
Authors: Misato Chimura, Tetsuari Onishi, Hiroya Kawai, Shinishiro Yamada, Yoshinori Yasaka
Journal: Circulation (2014)

Introduction: It has been reported that sympathetic nervous dysfunction by 123I-metaiodobenzylguanidine (MIBG) is associated with worse outcome in dilated cardiomyopathy (DCM) patients. However, the association between sympathetic nervous function and myocardial strain is not established. Hypothesis: Global longitudinal strain (GLS) by two-dimensional speckle-tracking echocardiography (2DSTE) is correlated with sympathetic nervous activity, and stratifies DCM patients at risk for cardiac events with a combination of sympathetic nervous activity. Methods: We studied 71 patients who had admitted to a cardiology department with heart failure at the initial visit (age 61±13 years, 45 males, LV ejection fraction (EF) 30±8 %). All patients underwent MIBG imaging for the delayed heart to mediastinum ratio (H/M), and echocardiography with conventional assessment including left atrial volume (LAV), LV end-diastolic and end-systolic volume (LVEDV, LVESV), LVEF, mitral regurgitation grade (MR), early transmitral flow to atrial contraction (E/A) and with 2DSTE analysis for GLS expressed with an absolute value. Cardiac events were assessed according to death and hospitalization with heart failure. Results: There were 21 cardiac events in the follow-up period for 4.9±2.3 years. Univariate regression analysis showed LAV, LVEDV, LVESV, LVEF, MR, E/A and GLS had a significant correlation with delayed H/M (all p &lt; 0.05). Multivariate regression analysis revealed that GLS was an independent predictor of delayed H/M. Dividing all patients into 4 groups by the median of GLS in patients with delayed H/M &gt;1.6 or≤1.6, the combination of the worse delayed H/M and the worse GLS was significantly associated with cardiac events (p=0.03). Conclusions: Left ventricular GLS is significantly correlated with delayed H/M and can be useful to stratify the risk in DCM patients with a combination of delayed H/M.
Screening for brain metastases (BM) in patients (pts) with stage III non-small cell lung cancer (NSCLC), magnetic resonance imaging (MRI) or dedicated contrast-enhanced computed tomography (dCE-CT)? A prospective observational study
Authors: J.J.A.O. Schoenmaekers, L. Hendriks, A.-M.C. Dingemans, D. De Ruysscher, G. Bootsma, W. Schreurs, M. Westenend, R. Houben, P. Hofman, M. De Booij
Journal: Annals of Oncology (2018)
Kinase fusions in colorectal cancers: A unique biologic subset
Authors: R. Madison, F. Pietrantonio, L. Juckett, C. Cremolini, J. Chung, L.A. Albacker, V.A. Miller, S.J. Klempner, M.B. Resnick, E. Yakirevich, S.-H.I. Ou, M. Fakih, A.B. Schrock, J.S. Ross, S.M. Ali
Journal: Annals of Oncology (2018)
P3.03-22 IL-1β as a New Early Predictive Biomarker for Non-Small Cell Lung Cancers Outcome
Authors: S. Missiroli, N. Tamburini, M. Perrone, P. Maniscalco, R. Gafà, G. Lanza, P. Pinton, G. Cavallesco, C. Giorgi
Journal: Journal of Thoracic Oncology (2018)
HBsAg seroclearance further reduces hepatocellular carcinoma risk after complete viral suppression with nucleos(t)ide analogues
Authors: Terry Cheuk-Fung Yip, Grace Lai-Hung Wong, Henry Lik-Yuen Chan, Yee-Kit Tse, Kelvin Long-Yan Lam, Grace Chung-Yan Lui, Vincent Wai-Sun Wong
Journal: Journal of Hepatology (2018)
P2.06-02 Feasibility of Intensity Modulated Radiotherapy After Pleurectomy/Decortication for Malignant Pleural Mesothelioma Patients
Authors: O. Arrieta, F. Lozano, M. Blake, Z. Zatarain-Barrón, L. Ramírez-Tirado, M. Salinas Padilla, F. Maldonado, J. Corona-Cruz
Journal: Journal of Thoracic Oncology (2018)
P2.01-83 Evaluation of Dynamic Thiol/Disulphide Homeostasis in Advance Non-Small Cell Lung Cancer and Small Cell Lung Cancer
Authors: M. Hizal, B. Bilgin, M.A. Sendur, M. Akinci, S. Neselioglu, O. Erel, B. Yalcin
Journal: Journal of Thoracic Oncology (2018)
Pilot study: Localizing target lymph node using a magnetic marker allows reliable and representative judgement of pathological responses after neo-adjuvant ipilimumab (IPI) + nivolumab (NIVO) in macroscopic stage III melanoma
Authors: A.C.J. van Akkooi, B. Schermers, V. Franke, M. Wouters, C.L. Zuur, W.M.C. Klop, E.A. Rozeman, B.A. van de Wiel, T.J.M. Ruers, C.U. Blank
Journal: Annals of Oncology (2018)
P1.04-16 Comparison of Clinical Response to Checkpoint Inhibitors in Advanced NSCLC with High PD-L1 Expression Tested on Cytology Versus Biopsy Samples
Authors: K. Guo, G. Kasymjanova, H. Wang, L. Sakr, D. Small, V. Cohen, C. Pepe, A. Spatz, J. Agulnik
Journal: Journal of Thoracic Oncology (2018)