An Independent Evaluation of the Accuracy and Usability of Electronic Adherence Monitoring Devices
Authors: Meghan E. McGrady, Christina E. Holbein, Aimee W. Smith, Caroline F. Morrison, Kevin A. Hommel, Avani C. Modi, Ahna L.H. Pai, Rachelle R. Ramsey
Journal: Annals of Internal Medicine (2018)

Letters18 September 2018An Independent Evaluation of the Accuracy and Usability of Electronic Adherence Monitoring DevicesMeghan E. McGrady, PhD, Christina E. Holbein, PhD, Aimee W. Smith, PhD, Caroline F. Morrison, PhD, RN, Kevin A. Hommel, PhD, Avani C. Modi, PhD, Ahna L.H. Pai, PhD, and Rachelle R. Ramsey, PhDMeghan E. McGrady, PhDCincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, Ohio (M.E.M., K.A.H., A.C.M., A.L.P., R.R.R.), Christina E. Holbein, PhDCincinnati Children's Hospital Medical Center, Cincinnati, Ohio (C.E.H., A.W.S.), Aimee W. Smith, PhDCincinnati Children's Hospital Medical Center, Cincinnati, Ohio (C.E.H., A.W.S.), Caroline F. Morrison, PhD, RNUniversity of Cincinnati, Cincinnati, Ohio (C.F.M.), Kevin A. Hommel, PhDCincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, Ohio (M.E.M., K.A.H., A.C.M., A.L.P., R.R.R.), Avani C. Modi, PhDCincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, Ohio (M.E.M., K.A.H., A.C.M., A.L.P., R.R.R.), Ahna L.H. Pai, PhDCincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, Ohio (M.E.M., K.A.H., A.C.M., A.L.P., R.R.R.), and Rachelle R. Ramsey, PhDCincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, Ohio (M.E.M., K.A.H., A.C.M., A.L.P., R.R.R.)Author, Article, and Disclosure Informationhttps://doi.org/10.7326/M17-3306 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Background: Approximately 50% of patients are nonadherent to their medications, and this is a primary cause of treatment failure, morbidity, and mortality (1, 2). As a result, it is associated with an estimated $300 billion in potentially avoidable U.S. health care costs each year (1, 2). Increasing adherence may improve health outcomes and reduce costs even more so than the advent of new medical treatments (1, 3). However, such efforts have been limited by the lack of objective measures of adherence (3). Electronic adherence monitoring devices (EAMDs) are the most objective and preferred measurement strategy for clinical practice and research ...References1. Sabate E. Adherence to Long-Term Therapies: Evidence for Action. Geneva: World Health Organization; 2003. Google Scholar2. DiMatteo MR. Variations in patients' adherence to medical recommendations: a quantitative review of 50 years of research. Med Care. 2004;42:200-9. [PMID: 15076819] CrossrefMedlineGoogle Scholar3. Haynes RB, McDonald H, Garg AX, Montague P. Interventions for helping patients to follow prescriptions for medications. Cochrane Database Syst Rev. 2002:CD000011. [PMID: 12076376] MedlineGoogle Scholar4. DE Bleser L, DE Geest S, Vincke B, Ruppar T, Vanhaecke J, Dobbels F. How to test electronic adherence monitoring devices for use in daily life: a conceptual framework. Comput Inform Nurs. 2011;29:489-95. [PMID: 21532468] doi:10.1097/NCN.0b013e31821a1555 CrossrefMedlineGoogle Scholar5. Chan AH, Harrison J, Black PN, Mitchell EA, Foster JM. Using electronic monitoring devices to measure inhaler adherence: a practical guide for clinicians. J Allergy Clin Immunol Pract. 2015;3:335-49. [PMID: 25840665] doi:10.1016/j.jaip.2015.01.024 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, Ohio (M.E.M., K.A.H., A.C.M., A.L.P., R.R.R.)Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio (C.E.H., A.W.S.)University of Cincinnati, Cincinnati, Ohio (C.F.M.)Disclaimer: The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.Acknowledgment: The authors thank Gabriella Breen, BS, for assistance with data management and manuscript formatting.Financial Support: Dr. McGrady is supported by the National Cancer Institute of the National Institutes of Health (award K07CA200668). Drs. Holbein and Morrison are supported by the Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health (award T32HD068223). Drs. McGrady and Ramsey received funding from the Center for Adherence and Self-Management at Cincinnati Children's Hospital Medical Center to support the collection and management of data.Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M17-3306.Reproducible Research Statement:Study protocol: Available at www.cincinnatichildrens.org/research/divisions/b/psychology/labs/mcgrady/projects. Statistical code: Not applicable. Data set: Available from Dr. McGrady (e-mail, Meghan.[email protected]org). 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