tbuckley/cabot-search huggingface dataset:
Long-term outcomes in patients with muscle-invasive bladder cancer after bladder-preserving combined-modality therapy: A pooled analysis of RTOG 8802, 8903, 9506, 9706, 9906, and 0233.
Authors: Raymond H. Mak, Daniel Hunt, William U. Shipley, Jason Alexander Efstathiou, William J. Tester, Michael P. Hagan, Donald S. Kaufman, Niall M. Heney, Anthony L. Zietman
Journal: Journal of Clinical Oncology (2012)

264 Background: Multiple prospective RTOG studies have evaluated bladder preserving combined-modality therapy (CMT) including local resection with chemo-radiation for the treatment of muscle invasive bladder cancer (MIBC) reserving cystectomy for salvage. Here we report a pooled analysis of long-term outcomes. Methods: We performed a pooled analysis of 468 patients (pts) with MIBC enrolled on six RTOG bladder preservation studies, including five Phase II studies: RTOG 8802, 9506, 9706, 9906, and 0233, and one phase III study: 8903. Overall survival (OS) was estimated with the Kaplan-Meier method, and disease specific survival (DSS), local failure (LF) and distant metastasis (DM) were estimated by the cumulative incidence method. Results: The median age of the pts was 66 (range, 34-93), and the majority had a Zubrod performance status (PS) of 0 (89.1%). The most common tumor histology was transitional cell carcinoma (94.2%). Clinical tumor stage distribution included 60.6% T2, 29.1% T3a, 6.2% T3b, and 3.9% T4a. A complete response to CMT was observed in 72.0% of pts. With a median follow-up of 4.29 years among all pts, and 7.80 years among survivors (n=205), the 5-year and 10-year results were as follows (Table). Examining outcomes by subgroups, higher clinical T-stage (T2 vs. T3/T4) was associated with decreased DSS (5-year DSS: 74% vs. 66%; 10-year DSS: 69% vs. 60%; p=0.05), and OS (5-year OS: 62% vs. 49%; 10-year OS: 41% vs. 30%; p=0.002). On multivariate analysis, after adjusting for age and PS, higher T-stage was associated with decreased DSS (Hazard ratio: 1.65; 95% confidence interval: 1.19-2.27; p=0.002). Among pts with non-transitional cell carcinoma histology (n=29), the 5-year and 10-year DSS was 66% and 60%, respectively, and 5-year and 10-year OS was 41% and 21%. Conclusions: This pooled analysis of RTOG trials of bladder preserving CMT for MIBC demonstrates long-term OS and DSS comparable to modern immediate cystectomy-based strategies with and without neoadjuvant chemotherapy. CMT can be considered as an alternative to radical cystectomy in selected pts. [Table: see text]
Abstract 9633: Human Blood and Cardiac Stem Cells Synergize to Enhance Cardiac Repair When Co-transplanted Into Ischemic Myocardium
Authors: Darryl R Davis, Nicholas Latham, Bin Ye, Bu-Khanh Lam, Drew Kuraitis, Marc Ruel, Erik J Suuronen, Duncan J Stewart
Journal: Circulation (2012)

Blood-derived circulatory angiogenic cells (CACs) and resident cardiac stem cells (CSCs) have both been shown to improve cardiac function after myocardial infarction (MI). However, whether one cell type is superior has long been an area of speculation with no head-to-head trial. In this study, we compared the effect of human CACs and CSCs, alone or in combination, on myocardial function in an immunodeficient mouse model of MI. Methods and Results- CACs and CSCs were cultured from left atrial appendages and blood samples obtained from patients undergoing clinically-indicated heart surgery. In hypoxic culture conditions designed to mirror ischemic myocardium, protein arrays demonstrated that CACs expressed a broader cytokine profile than CSCs (36 vs. 5, respectively; p&lt;0.05) with 3 cytokines in common. Co-culture of CACs and CSCs further enhanced the production of stromal cell derived factor-1α and vascular endothelial growth factor (p&lt;0.05). Conditioned media promoted equivalent vascular networks and endothelial progenitors recruitment with superior effects using co-cultured conditioned media (p&lt;0.05 vs. single cell cultures). Intramyocardial injection of CACs or CSCs alone improved left ventricular ejection fraction (LVEF) when injected one week after MI (p&lt;0.05 vs. vehicle (PBS) or normal human dermal fibroblasts (NHDF); Figure). Co-transplantation of CACs and CSCs together improved LVEF to a greater extent than either stem cell therapy alone (p&lt;0.05 vs. CAC or CSC injection alone). Conclusions- CACs and CSCs provide unique paracrine repertoires with equivalent effects on angiogenesis, stem cell migration and myocardial repair. Combination therapy with both cell types synergistically improves post infarct myocardial function greater than either therapy alone. This synergy is likely mediated by the complimentary paracrine signatures that promote revascularization and the growth of new myocardium.
A UBE2O-AMPKα2 Axis that Promotes Tumor Initiation and Progression Offers Opportunities for Therapy
Authors: Isabelle K. Vila, Yixin Yao, Goeun Kim, Weiya Xia, Hyejin Kim, Sun-Joong Kim, Mi-Kyung Park, James P. Hwang, Enrique González-Billalabeitia, Mien-Chie Hung, Su Jung Song, Min Sup Song
Journal: Cancer Cell (2017)

UBE2O is localized in the 17q25 locus, which is known to be amplified in human cancers, but its role in tumorigenesis remains undefined. Here we show that Ube2o deletion in MMTV-PyVT or TRAMP mice profoundly impairs tumor initiation, growth, and metastasis, while switching off the metabolic reprogramming of tumor cells. Mechanistically, UBE2O specifically targets AMPKα2 for ubiquitination and degradation, and thereby promotes activation of the mTOR-HIF1α pathway. Notably, inactivation of AMPKα2, but not AMPKα1, abrogates the tumor attenuation caused by UBE2O loss, while treatment with rapamycin or inhibition of HIF1α ablates UBE2O-dependent tumor biology. Finally, pharmacological blockade of UBE2O inhibits tumorigenesis through the restoration of AMPKα2, suggesting the UBE2O-AMPKα2 axis as a potential cancer therapeutic target.
Chromosomal defects Detected by SNP-Array-Based Karyotyping Are Independent Predictors of Survival in Acute Myeloid Leukemia (AML)
Authors: Ramon V. Tiu, Lukasz P Gondek, Bhavana Bhatnagar, Christine O’Keefe, Mikkael A. Sekeres, Xiao-Fei Wang, Mark J. Levis, Michael A McDevitt, Judith E. Karp, Jaroslaw P. Maciejewski
Journal: Blood (2008)
Outcomes after resection of pulmonary metastases in patients with colorectal cancer.
Authors: Kaihong Mi, Michael J. McNamara, Xuefei Jia, Yazeed Sawalha, Katherine Glass, Alok A. Khorana
Journal: Journal of Clinical Oncology (2016)

757 Background: Surgical resection of liver metastases provides a significant survival benefit, and potential for cure, in selected patients with metastatic colorectal cancer. There are very limited data on resection of lung metastases in patients with colorectal lung metastases. We evaluated outcomes after resection of lung metastases in patients with colorectal cancer. Methods: We conducted a retrospective cohort study in patients who underwent resection of pulmonary metastases between 2/2006 and 6/2013 at Cleveland Clinic. Clinical, pathologic, and outcome data were collected by electronic medical records review. Overall survival (OS) as the primary endpoint was summarized by Kaplan-Meier method and analyzed by log-rank tests. Results: The study population comprised 32 patients. Overall, 20 patients were male and median age at diagnosis of lung metastasis was 60.0 years (range 30.4-81.9). All patients had resection of primary tumor. Eleven patients had preoperative chemotherapy and 12 had adjuvant chemotherapy. Patients with unilateral metastases comprised the majority of patients (N = 22, 68.8%); 59% (N = 19) had a solitary metastasis. The median diameter of lung metastases was 20.5 mm (range 7.0 -50.0). Ten patients had concurrent liver metastases, eight of whom had liver resection as well. Overall, 31% (10/32) of patients recurred, with 50% (16/32) of recurrences in the lung, and 28% died. Estimated median OS was 55.0 months. Estimated 5-year OS was 32% ± 17%. Higher CEA level ( ≥ 4.5 ng/mL) at the time of diagnosis of lung metastasis was associated with worsened OS (p = 0.026). Other potential prognostic factors, such as laterality, number of lung metastases, and extrapulmonary lesions, were not associated with overall survival in this study population. Conclusions: Our study showed resection of lung metastases in select patients with colorectal cancer can be associated with prolonged survival in the range seen with resection of liver metastases. Higher CEA level at time of diagnosis of lung metastasis is associated with poorer prognosis. More data are necessary to identify approaches to patient selection in the metastatic colorectal setting.
Consolidation Therapy with Subcutaneous (SC) Alemtuzumab Results in Severe Infectious Toxicity in Previously Untreated CLL Patients Who Achieve a Complete Response (CR) after Fludarabine and Rituximab (FR) Induction Therapy: Interim Safety Analysis of the CALGB Study 10101.
Authors: Thomas S. Lin, Kathleen A. Donohue, Margaret S. Lucas, John C. Byrd, Elizabeth M. Bengtson, Bercedis L. Peterson, Richard A. Larson
Journal: Blood (2007)
Genetic instability after radiotherapy in prostate cancer: TMRSS2-ERG fusion in salvage radical prostatectomies.
Authors: David J. K. P. Pfister, Katarina Lindemann, Daniel Porres, Charlotte Piper, Ruth Knuchel, Axel Heidenreich
Journal: Journal of Clinical Oncology (2013)

182 Background: TMRSS2-ERG fusion is the most frequent genetic abberation in prostate cancer. Till now its expression is not associated with a poorer prognosis. In cell line models the fusion can be induced by exogenic factors as hormonal treatment or radiotherapy. Additionally its expression leads to different sensitivities to radiotherapy in different cell line models. We analyzed TMPRSS2-ERG fusion for the first time in patients with salvage radical prostatectomy and correlated it to radical prostatectomy specimen without prior treatment. Methods: 38 radical prostatectomy specimen of patients formaly treated with radiotherapy and recurrent disease and 38 primary RPEs were analyzed for ERG expression (15 external RT, ERT, 18 LDR, 5 HDR). ERG expression was detected by a highly sensitive monoclonal antibody as described recently. Results: Median PSA preoperatively was 3.6 (0.1-27) ng/ml. More patients had locally advanced dieseasae in the final pathologic specimen (17:21). In 18 (47,4%) patients (8 (44,4%) in LDR, 3 (60%) in HDR, 7(46,7%) in ERT) an ERG expression was detected. There is no difference in the ERG expression compared to an independend cohort of radical prostatectomy specimen (47,4% versus 47,4%). Conclusions: We are the first to analyze ERG expression in salvage radical prostatectomies. In this cohort there is no difference in the ERG expression rate after applied radiotherapy. The risk of inducing a gene fusion by external influence as seen in cell cultures cannot be transferred to daily practice.
What do we GANE with age?
Authors: Matthew R. Nassar, Rasmus Bruckner, Ben Eppinger
Journal: Behavioral and Brain Sciences (2016)

Abstract Mather and colleagues provide an impressive cross-level account of how arousal levels modulate behavior, and they support it with data ranging from receptor pharmacology to measures of cognitive function. Here we consider two related questions: (1) Why should the brain engage in different arousal levels? and (2) What are the predicted consequences of age-related changes in norepinephrine signaling for cognitive function?
Role of the IL-33-ST2 axis in sepsis
Authors: Hui Xu, Heth R. Turnquist, Rosemary Hoffman, Timothy R. Billiar
Journal: Military Medical Research (2017)

Sepsis remains a major clinical problem with high morbidity and mortality. As new inflammatory mediators are characterized, it is important to understand their roles in sepsis. Interleukin 33 (IL-33) is a recently described member of the IL-1 family that is widely expressed in cells of barrier tissues. Upon tissue damage, IL-33 is released as an alarmin and activates various types of cells of both the innate and adaptive immune system through binding to the ST2/IL-1 receptor accessory protein complex. IL-33 has apparent pleiotropic functions in many disease models, with its actions strongly shaped by the local microenvironment. Recent studies have established a role for the IL-33-ST2 axis in the initiation and perpetuation of inflammation during endotoxemia, but its roles in sepsis appear to be organism and model dependent. In this review, we focus on the recent advances in understanding the role of the IL-33/ST2 axis in sepsis.
A Phase II Trial of Combination Therapy with Thalidomide, Arsenic Trioxide, Dexamethasone, and Ascorbic Acid (TADA) in Patients with Chronic Idiopathic Myelofibrosis (CIMF) or Overlap Myelodysplastic/Myeloproliferative Diseases (MDS/MPD).
Authors: Mikkael A. Sekeres, Jaroslaw P. Maciejewski, Matt Kalaycio, Julie Nichols, Ronald Sobecks, Anjali Advani, Josephine Chan, Naomi Galili, Fatima Raza, Jessica Wasserman, Peter Westervelt, Azra Raza
Journal: Blood (2006)
Feasibility of Administering Oblimersen (G3139; Genasense) with Imatinib Mesylate in Patients with Imatinib Resistant Chronic Myeloid Leukemia (CML) - Cancer and Leukemia Group B Study 10107.
Authors: Meir Wetzler, Daohai Yu, Olatoyosi Odenike, Eric J. Feldman, David D. Hurd, Eva Hoke, Vera Hars, Richard A. Larson
Journal: Blood (2005)
Identification of a First-in-Class PRMT5 Inhibitor with Potent in Vitro and in Vivo Activity in Preclinical Models of Mantle Cell Lymphoma
Authors: Elayne Penebre, Kristy G Kuplast, Christina R Majer, L. Danielle Johnston, Nathalie Rioux, Michael Munchhof, Lei Jin, P. Ann Boriak-Sjodin, Tim J Wigle, Suzanne L Jacques, Kip A West, Trupti Lingaraj, Kimberly Stickland, Scott A Ribich, Alejandra Raimondi, Margaret Porter-Scott, Nigel J Waters, Roy M Pollock, Jesse J Smith, Olena Barbash, Ryan G. Kruger, Robert A Copeland, Mikel P Moyer, Richard Chesworth, Kenneth W Duncan
Journal: Blood (2014)
Functional Vanilloid Receptor VR1 Is Expressed on Megakaryocytes and Platelets, and Acts as a Sensor for Hypertheimia Generating Endocannabinoids.
Authors: Ikuro Maruyama, Kentaro Soejima, Toshiaki Shimi, Kazuhiro Abeyama, Teruto Hashiguchi
Journal: Blood (2004)
Outcome of Nodular Lymphocyte Predominant Hodgkin Lymphoma Patients Treated with or without Rituximab
Authors: Heidi Mocikova, Jozef Michalka, Jan Koren, Pavla Stepankova, Alexander Wild, Ludek Raida, Jana Markova, Zdenek Kral, Marek Trneny, Karel Indrak, Jiri Mayer, Tomas Kozak
Journal: Blood (2012)
A Gene-wide Association Study of Heart Rate Variability at Rest and During Stress: 8 Genes in the Parasympathetic Pathway
Authors: Xiaoling Wang, Harriette Riese, Shaoyong Su, Haidong Zhu, Yanbin Dong, Xiuhua Ding, Julian F. Thayer, Frank Treiber, Harold Snieder
Journal: Circulation (2009)
An outbreak of humidifier fever on a warship
Authors: Mark Edmondstone
Journal: BMJ (2017)

During the summer of 1981 a sailor from the warship HMS Sheffield mentioned a curious illness affecting his messmates. They would embark after weekend leave and, by late afternoon on Monday, they would have chills, aches, sweats, dry coughs, and sore throats. These symptoms would largely subside through the week and, by the weekend, had …
BMS-354825, a Dual SRC/ABL Kinase Inhibitor, Displays Potent Anti-Tumor Activity in a Model of Intracranial CML Growth.
Authors: Robert Wild, Stephen Castaneda, Christine Flefleh, Krista Fager, Ivan Inigo, David Kan, Richard Smykla, Amy Camuso, Kelly McGlinchey, Mei-Li Wen, Feng Roger Luo, Robert Borzilleri, Louis Lombardo, Robert Kramer, Francis Y. Lee
Journal: Blood (2004)
Gene Expression Profiling of Highly Purified Malignant and Non-Malignant Cells: Characterization of the Tumor-Microenvironment Cellular Synapse in De Novo Follicular Lymphoma (FL).
Authors: Karin Tarte, Céline Pangault, John de Vos, Philippe Ruminy, Fabienne Sauvee, Patrick Tas, Jean-Michel Picquenot, Hervé Tilly, Thierry Lamy, Christian Bastard, Thierry Fest
Journal: Blood (2007)
Xanthine oxidoreductase activity is correlated with insulin resistance and subclinical inflammation in young humans
Authors: Kahori (Watanabe) Washio, Yoshiki Kusunoki, Takayo Murase, Takashi Nakamura, Keiko Osugi, Mana Ohigashi, Tadahiko Sukenaga, Fumihiro Ochi, Toshihiro Matsuo, Tomoyuki Katsuno, Yuji Moriwaki, Tetsuya Yamamoto, Mitsuyoshi Namba, Hidenori Koyama
Journal: Metabolism (2017)
Prolonged Survival in Patients with Angioimmunoblastic T-Cell Lymphoma (AIL) after High-Dose Chemotherapy and Autologous Stem Cell Transplantation (ASCT). The GELTAMO Experience.
Authors: Jose Rodriguez, Maria Dolores Caballero, Antonio Gutierrez, Marco Gandarillas, Angel Leon, Jesus Ojanguren, Ana Sureda, Armando Lopez-Guillermo, Dolores Carrera, Mauricio Bendandi, Reyes Arranz, Jose Moraleda, Jose Maria Ribera, Carmen Albo, Alfonso Morales, Juan Carlos Garcia, Pascual Fernandez, Guillermo Cañigral, Juan Bergua, Eulogio Conde
Journal: Blood (2005)
Clinical Features of Idiopathic Erythrocytosis Compared to Polycythemia Vera JAK-2 V617F Positive and Negative Patients
Authors: Roberto Latagliata, Agostino Tafuri, Antonio Spadea, Antonietta Ferretti, Daniela Diverio, Massimo Breccia, Mariella D'Andrea, Alessandro Andriani, Marco Montanaro, Michele Cedrone, Enrico Montefusco, Angela Rago, Odoardo Maria Olimpieri, Antonino Bagnato, Francesca Biondo, Federico Vozella, Maria Cantonetti, Maria Concetta Petti, Giuliana Alimena
Journal: Blood (2011)
Proteolysis of MLL Family Proteins Is Essential for Taspase1−Orchestrated Cell Cycle Progression.
Authors: James J. Hsieh, Shugaku Takeda, David Y. Chen, Todd D. Westergard, Jill K. Fisher, Jeffrey A. Rubens, Satoru Sasagawa, Jason T. Kan, Stanley J. Korsmeyer, Emily H. Cheng
Journal: Blood (2006)
OCT-2 Expression and OCT-2/BOB.1 Co-Expression Predict Prognosis in Patients with Newly Diagnosed Acute Myelogenous Leukemia.
Authors: Kathleen Lim, Sarah Gibson, Tao Jin, Eric Hsi, Matt Kalaycio, Edward A. Copelan, Mikkael A. Sekeres, Ronald Sobecks, Anjali Advani
Journal: Blood (2008)
Clinical Significance and Risk Factors of Delayed-Onset Neutropenia (DON) after Autologous Stem Cell Transplantation (ASCT) for B-Cell Non-Hodgkin Lymphoma: A Single-Institute Analysis.
Authors: Harumi Kato, Keitaro Matsuo, Kazuhito Yamamoto, Yasuhiro Oki, Chihiro Kondo, Yoshitoyo Kagami, Yasuo Morishima
Journal: Blood (2007)
A Phase II Trial of Radioimmunotherapy-Based Autologous Transplantation with I-131 Tositumomab, Cyclophosphamide and Etoposide in Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Authors: Paul S Martin, Isaac C Jenkins, Theodore A Gooley, Damian J Green, John M Pagel, Sally J Lundberg, Lacey M Hedine, Joseph G Rajendran, Andrew T Shields, Darrell R Fisher, David G Maloney, Frederick R Appelbaum, Ryan D Cassaday, Oliver W Press, Ajay K. Gopal
Journal: Blood (2015)
QOL-13GLIOBLASTOMAS LOCATED IN THE RIGHT HEMISPHERE ARE ASSOCIATED WITH WORSE QUALITY OF LIFE
Authors: Christian Iorio-Morin, Philippe Goffaux, Maxime Descoteau, Kevin Whittingstall, David Fortin
Journal: Neuro-Oncology (2015)

INTRODUCTION: Glioblastoma is the most frequent primary brain tumor. Because it is currently incurable, the goal of therapy is the optimization of the patient's quality of life (QOL). While maximal surgical resection has been shown to improve survival and QOL, not all tumors can be safely resected. Tumor location is critical in screening surgical candidates, yet the impact of tumor location on QOL has never been convincingly demonstrated, possibly due to the prohibitively high sample size that standard statistical analyses would require. By using a novel computer-driven algorithm, we set out to investigate the impact of tumor location on QOL. METHODS: The tumors of fourty consecutive glioblastoma patients were segmented and registered to a Talairach-space standard brain image. The Euclidian distance between 90 brain regions and each tumor's margin was calculated and correlated to the patients' self-reported QOL as measured by the SNAS questionnaire. Multiple linear regression analyses were performed between QOL, tumor location and clinical parameters. RESULTS: QOL was statistically associated with proximity to three areas: the right para-hypocampal gyrus, the right posterior cingulate cortex and the right postcentral gyrus. We postulate that the adverse relation between proximity to these areas and QOL results from disruption in large-scale networks involved in high-order functions such as visuospatial memory. While harder to detect with a bedside clinical examination, such deficits are likely more impactful on QOL than those related to the motor cortex or Broca's area. CONCLUSION: Tumor proximity to the right para-hypocampal gyrus, the right posterior cingulate cortex and the right postcentral gyrus are associated with decreased QOL, probably via an impact in visuospatial functionning. While traditionally considered non-eloquent, these affected areas have more impact on QOL than any other brain region and this should be considered in the management strategies of glioma patients.
Persistent Opioid Use After Major Surgery
Authors: Xiulu Ruan, Hong Wu, Alan David Kaye
Journal: JAMA Surgery (2017)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Surgery HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Surgery journal
Prevalence of Coronary Heart Disease in Patients with Hemophilia: a Nationwide Study in Brazil.
Authors: Claudia Bley, Fabio P S Santos, Antonio E P Pesaro, Ricardo Helman, Sergio A Oliveira, Elcio Pfeferman, Carlos V Serrano, Ana S L Saraiva, Elbio D Amico, Nelson Hamerschlak
Journal: Blood (2009)
Direct Transcriptional Repression of BCL2 by BCL6 in Germinal Centre B Cells and Its Disruption in B Cell Lymphomas with BCL2 Locus Alterations
Authors: Erich Piovan, Masumichi Saito, Katia Basso, Urban Novak, Qiong Shen, Laura Pasqualucci, Riccardo Dalla-Favera
Journal: Blood (2008)
Inhibition of ERK1/2 Activity by the MEK1/2 Inhibitor AZD6244 (ARRY-142886) Induces Human Multiple Myeloma Cell Apoptosis in the Bone Marrow Microenvironment: A New Therapeutic Strategy for MM.
Authors: Yu-Tzu Tai, Xian-Feng Li, Iris Breitkreutz, Weihua Song, Peter Burger, Matthew Rumizen, Teru Hideshima, Klaus Podar, Irene Ghobrial, Robert Schlossman, Paul Richardson, Nikhil C. Munshi, Kenneth C. Anderson
Journal: Blood (2006)