Premature Mortality From Drug Overdoses: A Comparative Analysis of 13 Organisation for Economic Co-operation and Development Member Countries With High-Quality Death Certificate Data, 2001 to 2015
Authors: Yingxi Chen, Meredith S. Shiels, David Thomas, Neal D. Freedman, Amy Berrington de González
Journal: Annals of Internal Medicine (2018)

Letters5 March 2019Premature Mortality From Drug Overdoses: A Comparative Analysis of 13 Organisation for Economic Co-operation and Development Member Countries With High-Quality Death Certificate Data, 2001 to 2015Yingxi Chen, MD, PhD, Meredith S. Shiels, PhD, David Thomas, PhD, Neal D. Freedman, PhD, and Amy Berrington de González, DPhilYingxi Chen, MD, PhDNational Cancer Institute, Rockville, Maryland (Y.C., M.S.S., N.D.F., A.B.), Meredith S. Shiels, PhDNational Cancer Institute, Rockville, Maryland (Y.C., M.S.S., N.D.F., A.B.), David Thomas, PhDNational Institute on Drug Abuse, Bethesda, Maryland (D.T.), Neal D. Freedman, PhDNational Cancer Institute, Rockville, Maryland (Y.C., M.S.S., N.D.F., A.B.), and Amy Berrington de González, DPhilNational Cancer Institute, Rockville, Maryland (Y.C., M.S.S., N.D.F., A.B.)Author, Article, and Disclosure Informationhttps://doi.org/10.7326/M18-2415 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Background: Drug overdose mortality rates in the United States have more than doubled during the 21st century, reaching an estimated 63 632 deaths in 2016 (1). Recent increases have also been reported in other high-income countries, raising concerns that the problem has grown internationally.Objective: To compare the trends and patterns in premature mortality rates due to drug overdose in 13 Organisation for Economic Co-operation and Development member countries with comparable, high-quality death certificate data between 2001 and 2015.Methods and Findings: We used the World Health Organization Mortality Database to obtain the annual number of deaths due to drug overdose ...References1. Hedegaard H, Warner M, Miniño AM. Drug Overdose Deaths in the United States, 1999–2016. NCHS Data Brief no 294. Hyattsville, MD: National Center for Health Statistics; 2017. Google Scholar2. Clegg LX, Hankey BF, Tiwari R, Feuer EJ, Edwards BK. Estimating average annual per cent change in trend analysis. Stat Med. 2009;28:3670-82. [PMID: 19856324] doi:10.1002/sim.3733 CrossrefMedlineGoogle Scholar3. Dasgupta N, Beletsky L, Ciccarone D. Opioid crisis: no easy fix to its social and economic determinants. Am J Public Health. 2018;108:182-6. [PMID: 29267060] doi:10.2105/AJPH.2017.304187 CrossrefMedlineGoogle Scholar4. European Monitoring Centre for Drugs and Drug Addiction. European drug report 2018. Trends and developments. June 2018. Accessed at www.emcdda.europa.eu/publications/edr/trends-developments/2018 on 20 August 2018. Google Scholar5. Roxburgh A, Hall WD, Dobbins T, Gisev N, Burns L, Pearson S, et al. Trends in heroin and pharmaceutical opioid overdose deaths in Australia. Drug Alcohol Depend. 2017;179:291-8. [PMID: 28826104] doi:10.1016/j.drugalcdep.2017.07.018 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: National Cancer Institute, Rockville, Maryland (Y.C., M.S.S., N.D.F., A.B.)National Institute on Drug Abuse, Bethesda, Maryland (D.T.)Disclosures: Authors have disclosed no conflicts of interest. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M18-2415.Reproducible Research Statement:Study protocol: Not available. Statistical code and data set: Available from Dr. Chen (e-mail, Yingxi.[email protected]gov).This article was published at Annals.org on 13 November 2018. 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