Cannabis for Pain and Posttraumatic Stress Disorder: More Consensus Than Controversy or Vice Versa?
Authors: Sachin Patel
Journal: Annals of Internal Medicine (2017)

Editorials5 September 2017Cannabis for Pain and Posttraumatic Stress Disorder: More Consensus Than Controversy or Vice Versa?Sachin Patel, MD, PhDSachin Patel, MD, PhDFrom Vanderbilt Psychiatric Hospital, Nashville, Tennessee.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/M17-1713 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail The scientific evidence for the effectiveness and safety of cannabis and cannabinoid products in treating medical and psychiatric disease has recently come under substantial scrutiny. This surge in methodologically rigorous analysis of the evidence supporting cannabis-based therapeutics is driven in part by recent, dramatic, and ongoing changes in the accessibility of cannabis caused by U.S. state-level antiprohibition movements. In this context, clinicians, policymakers, and the public are increasingly interested in understanding the scientific evidence base underlying potential indications for medical cannabis use. This issue of Annals of Internal Medicine includes 2 such analyses, 1 focusing on pain and the other ...References1. Nugent SM, Morasco BJ, O'Neil ME, Freeman M, Low A, Kondo K, et al. The effects of cannabis among adults with chronic pain and an overview of general harms. A systematic review. Ann Intern Med. 2017;167:319-31. doi:10.7326/M17-0155 LinkGoogle Scholar2. Serpell M, Ratcliffe S, Hovorka J, Schofield M, Taylor L, Lauder H, et al. A double-blind, randomized, placebo-controlled, parallel group study of THC/CBD spray in peripheral neuropathic pain treatment. Eur J Pain. 2014;18:999-1012. [PMID: 24420962] doi:10.1002/j.1532-2149.2013.00445.x CrossrefMedlineGoogle Scholar3. Park JY, Wu LT. Prevalence, reasons, perceived effects, and correlates of medical marijuana use: a review. Drug Alcohol Depend. 2017;177:1-13. [PMID: 28549263] doi:10.1016/j.drugalcdep.2017.03.009 CrossrefMedlineGoogle Scholar4. O'Neil ME, Nugent SM, Morasco BJ, Freeman M, Low A, Kondo K, et al. Benefits and harms of plant-based cannabis for posttraumatic stress disorder. A systematic review. Ann Intern Med. 2017;167:332-40. doi:10.7326/M17-0477 LinkGoogle Scholar5. National Academies of Sciences, Engineering, and Medicine. The Health Effects of Cannabis and Cannabinoids: The Current State of Evidence and Recommendations for Research. Washington, DC: National Academies Pr; 2017. doi:10.17226/24625 CrossrefGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Vanderbilt Psychiatric Hospital, Nashville, Tennessee.Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M17-1713.Corresponding Author: Sachin Patel, MD, PhD, Vanderbilt Psychiatric Hospital, 1601 23rd Avenue South, Nashville, TN 37232; e-mail, Sachin.[email protected]edu.This article was published at Annals.org on 15 August 2017. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoBenefits and Harms of Plant-Based Cannabis for Posttraumatic Stress Disorder Maya E. O'Neil , Shannon M. Nugent , Benjamin J. Morasco , Michele Freeman , Allison Low , Karli Kondo , Bernadette Zakher , Camille Elven , Makalapua Motu'apuaka , Robin Paynter , and Devan Kansagara The Effects of Cannabis Among Adults With Chronic Pain and an Overview of General Harms Shannon M. Nugent , Benjamin J. Morasco , Maya E. O'Neil , Michele Freeman , Allison Low , Karli Kondo , Camille Elven , Bernadette Zakher , Makalapua Motu'apuaka , Robin Paynter , and Devan Kansagara Metrics Cited byNatural Cannabinoids as Templates for Sleep Disturbances TreatmentsUse of Medicinal Cannabis and Synthetic Cannabinoids in Post-Traumatic Stress Disorder (PTSD): A Systematic ReviewPatient-reported use of medical cannabis for pain, anxiety, and depression symptoms: Systematic review and meta-analysisEvidence lacking to support cannabis for treating PTSD, chronic painMarijuana for Back Pain: A Mystery Without Any Clues 5 September 2017Volume 167, Issue 5Page: 355-356KeywordsCannabinoidsCannabisCannabis useClinical trialsDisclosureNeuropathic painPainPosttraumatic stress disorderSleepSystematic reviews ePublished: 15 August 2017 Issue Published: 5 September 2017 Copyright & PermissionsCopyright © 2017 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...