Low-Dose Aspirin to Reduce the Risk for Myocardial Infarction Among Patients With Coronary Stents Undergoing Noncardiac Surgery
Authors: Raffaele Piccolo, Stephan Windecker
Journal: Annals of Internal Medicine (2017)

Editorials20 February 2018Low-Dose Aspirin to Reduce the Risk for Myocardial Infarction Among Patients With Coronary Stents Undergoing Noncardiac SurgeryRaffaele Piccolo, MD, PhD and Stephan Windecker, MDRaffaele Piccolo, MD, PhDBern University Hospital, University of Bern, Bern, Switzerland (R.P., S.W.)Search for more papers by this author and Stephan Windecker, MDBern University Hospital, University of Bern, Bern, Switzerland (R.P., S.W.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/M17-2954 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Percutaneous coronary intervention (PCI) is one of the most frequent therapeutic procedures worldwide. The number of patients who have coronary stents implanted continues to increase because of the predominant use of PCI for myocardial revascularization in the setting of acute coronary syndromes and symptomatic stable coronary artery disease (1). Surgery is also widely done, and more than 200 million adults have major noncardiac surgery annually (2). As a result, it is unsurprising that approximately 5% to 25% of patients having PCI may require noncardiac surgery within 5 years after stent implantation (3). Cardiovascular adverse events are the leading cause of ...References1. Piccolo R, Giustino G, Mehran R, Windecker S. Stable coronary artery disease: revascularisation and invasive strategies. Lancet. 2015;386:702-13. [PMID: 26334162] doi:10.1016/S0140-6736(15)61220-X CrossrefMedlineGoogle Scholar2. Weiser TG, Regenbogen SE, Thompson KD, Haynes AB, Lipsitz SR, Berry WR, et al. An estimation of the global volume of surgery: a modelling strategy based on available data. 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[PMID: 22706835] doi:10.1001/jama.2012.5502 CrossrefMedlineGoogle Scholar5. van Waes JA, Nathoe HM, de Graaff JC, Kemperman H, de Borst GJ, Peelen LM, et al; Cardiac Health After Surgery (CHASE) Investigators. Myocardial injury after noncardiac surgery and its association with short-term mortality. Circulation. 2013;127:2264-71. [PMID: 23667270] doi:10.1161/CIRCULATIONAHA.113.002128 CrossrefMedlineGoogle Scholar6. Devereaux PJ, Mrkobrada M, Sessler DI, Leslie K, Alonso-Coello P, Kurz A, et al; POISE-2 Investigators. Aspirin in patients undergoing noncardiac surgery. N Engl J Med. 2014;370:1494-503. [PMID: 24679062] doi:10.1056/NEJMoa1401105 CrossrefMedlineGoogle Scholar7. Graham MM, Sessler DI, Parlow JL, Biccard BM, Guyatt G, Leslie K, et al. Aspirin in patients with previous percutaneous coronary intervention undergoing noncardiac surgery. Ann Intern Med. 2018;168:237-44. doi:10.7326/M17-2341 LinkGoogle Scholar8. 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[PMID: 27036918] doi:10.1016/j.jacc.2016.03.513 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Bern University Hospital, University of Bern, Bern, Switzerland (R.P., S.W.)Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M17-2954.Corresponding Author: Stephan Windecker, MD, Chairman and Professor, Department of Cardiology, Bern University Hospital, University of Bern, 3010 Bern, Switzerland; e-mail, stephan.[email protected]ch.Current Author Addresses: Drs. Piccolo and Windecker: Department of Cardiology, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.This article was published at Annals.org on 14 November 2017. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoAspirin in Patients With Previous Percutaneous Coronary Intervention Undergoing Noncardiac Surgery Michelle M. Graham , Daniel I. Sessler , Joel L. Parlow , Bruce M. Biccard , Gordon Guyatt , Kate Leslie , Matthew T.V. Chan , Christian S. Meyhoff , Denis Xavier , Alben Sigamani , Priya A. Kumar , Marko Mrkobrada , Deborah J. Cook , Vikas Tandon , Jesus Alvarez-Garcia , Juan Carlos Villar , Thomas W. Painter , Giovanni Landoni , Edith Fleischmann , Andre Lamy , Richard Whitlock , Yannick Le Manach , Meylin Aphang-Lam , Juan P. Cata , Peggy Gao , Nicolaas C.S. Terblanche , Pamidimukkala V. Ramana , Kim A. Jamieson , Amal Bessissow , Gabriela R. Mendoza , Silvia Ramirez , Pierre A. Diemunsch , Salim Yusuf , and P.J. Devereaux Metrics 20 February 2018Volume 168, Issue 4Page: 289-290KeywordsAspirinCardiovascular disease riskDisclosureHemorrhageMyocardial infarctionPercutaneous coronary interventionStable coronary artery diseaseStent implantationSurgeryTroponin ePublished: 14 November 2017 Issue Published: 20 February 2018 Copyright & PermissionsCopyright © 2017 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...