Conference on Articular Cartilage
Journal: Annals of the Rheumatic Diseases (1975)

AbstractIntroductionI. Structure of articular cartilageMicroscopical appearance and organization of articular cartilage surfacesScanning electron microscope study of normal human articular cartilageSequential changes in superficial defects in articular cartilage studied with the scanning electron microscopeCartilage fibrillation versus ink-staining patterns: Scanning electron microscope studyStain distribution with alcian blue in articular cartilageI. Short communicationsSome new morphological data on histogenesis of articular cartilageMatrix structure in articular cartilageThree-dimensional observations of articular cartilage matrixUltrastructural aspects of normal and osteoarthrotic cartilageScanning electron microscopy of human osteoarthrotic cartilageII. Chemistry of the matrixStructure and stability of proteoglycan aggregatesStructure of cartilage proteoglycansInteraction of cartilage collagen fibrils and proteoglycans: Application of fluorescent labelling techniques for assay of enzymes degrading cartilageChain composition of pepsin-solubilized collagen from normal bovine and osteoarthrotic human articular cartilagePassive agglutination method using collagen-coated tanned sheep erythrocytes to demonstrate collagen-glycosaminoglycan interactionII. Short communicationsProcollagen of chick xyphoid cartilageNature and location of crosslinks in cartilage collagenDiscontinuous nature of the protein-keratan sulphate core of cartilage proteoglycanConcentration, distribution, and metabolism of glycosaminoglycans in different layers of normal human articular cartilageVariations in glycosaminoglycans with surface site in human knee joint cartilageCharged group behaviour in cartilage proteoglycans in relation to pHEquilibria of calcium and phosphate ions in human articular cartilageIII. MetabolismNucleotide sugar metabolism in glycosaminoglycan biosynthesisBiosynthesis of proteoglycans in cartilageCartilage turnoverIII. Short communicationsEffect of in vitro incubation on distribution and synthesis of glycosaminoglycans of articular cartilageEffect of antiproteoglycan serum and Hyaluronidase on metabolic functions of calf cartilage cells in vitroOverlabelling of chondroitin sulphate (ChS) chains after application of specific inhibitors of their biosynthesisSynthesis of cerebroside sulphatides in human articular cartilageCircadian rhythms in the excretion of urinary acid glycosaminoglycansIV. Enzymes and degradationEnzymes involved in degradation of cartilage in osteoarthrosisBreakdown of protein-polysaccharide complexes by cartilage proteasesThe possible function of lysozyme in cartilage metabolismIV. Short communicationsEvidence for secretion of a proteolytic enzyme from rheumatoid pannus and synoviumAction of rheumatoid synovial collagenase on cartilage collagenMechanism of cartilage and synovial fluid hyaluronate degradation by polysaccharidasesResponse of articular cartilage in organ culture to growth hormoneRelease and degradation of sulphated proteoglycans and collagen from the cell layer of human chondrocytesStudies on cartilage vascularizationV.A. Functional propertiesFluid transport in cartilageFundamental fluid transport mechanisms through articular cartilageAn approximate equation for weeping lubrication, solved with an electrical analoguePurification and properties of articular lubricantAn overall view of synovial joint lubricationV.A. Short communicationsProteins associated with hyaluronic acidFormation of lubricating monolayers at the cartilage surfaceLubrication defect of immobilized connective tissue matrices: Study of the biomechanical and biochemical characteristics of normal and immobilized rabbit kneeV.B. Functional propertiesSome aspects of the mechanical behaviour of articular cartilageIn vitro fatigue testing of articular cartilageMechanical properties of articular cartilage and their relationship to matrix degradation and ageContact pressures in the loaded cadaver human hipV.B. Short communicationsA simple mechanical model of articular cartilageA new approach to the determination of the elastic modulus of articular cartilageWear properties of articular cartilageLoad bearing function of the menisci of the knee jointVI. Pathogenesis of osteoarthrosisPathogenesis of osteoarthrosis: An hypothesisArticular cartilage lesions in the Liverpool populationContribution to the study of the initial stage of cartilage degenerationBone density in osteoarthrosisMechanical factors in the aetiology of osteoarthrosisVI. Short communicationsHistological changes in osteoarthrotic femoral head cartilageCartilage of the patella and its degeneration: Topographical variation of the glycosaminoglycan contentUltrastructural and histological studies on articular cartilage in experimental osteoarthrosisProteoglycan aggregation in early experimental osteoarthrosisExperimentally-induced osteoarthrosis in the dog: Collagen biosynthesis in control and fibrillated articular cartilageExperimental evidence for an injury threshold for articular cartilageEarly loss of glycosaminoglycans in experimental haemarthrosis in dogsOsteocyte death in rheumatic diseasesDifferentiation and maintenance of articular (secondary) cartilage on avian membrane bonesImmunocytochemical and historical studies of a reversible transformation of chondrocytes in degraded cartilage matrix to a fibroblast-like morphologyConclusions of a working party of morbid anatomistsBibliography