tbuckley/cabot-search huggingface dataset:
Drop in general practice teaching in medical schools angers GP leaders
Authors: Matthew Limb
Journal: BMJ (2015)

GP leaders say that they are “astonished” and “outraged” at new research findings that show a drop in teaching time for general practice in UK medical schools.

The study found that time spent training students in general practice may be “insufficient” to produce the workforce that the NHS needs to deliver more community based care in the future. Responding to the findings Maureen Baker, who chairs the Royal College of General Practitioners, said, “Failure to promote general practice as a career by universities could have a devastating impact on the profession and the NHS as a whole.”

Researchers surveyed medical schools to establish medical students’ current exposure to general practice and compared this with past provision, as well as with postgraduate provision. They …
MEASURING PEDIATRIC CARDIAC INTENSIVE CARE UNIT QUALITY IN MEDICAL ADMISSIONS
Authors: Michael Gaies, Nancy Ghanayem, Jeffrey Alten, John Costello, Javier Lasa, Nikhil Chanani, Andrew Shin, Lauren Retzloff, Wenying Zhang, Sara Pasquali, Mousumi Banerjee, Sarah Tabbutt
Journal: Journal of the American College of Cardiology (2018)
Doctors leaving training are to be surveyed to improve career advice
Authors: Tom Moberly
Journal: BMJ (2015)

All doctors who choose not to move straight from the foundation programme into specialty training will be surveyed to help improve the careers advice given to doctors in training.

The BMA has been asked to work with appropriate bodies to survey “all foundation year 2 doctors who opt out of progressing directly into specialty training.” The request formed part of a motion on training and education that was …
<sup>68</sup>Ga-BBN-RGD PET/CT for GRPR and Integrin α<sub>v</sub>β<sub>3</sub> Imaging in Patients with Breast Cancer
Authors: Jingjing Zhang, Feng Mao, Gang Niu, Li Peng, Lixin Lang, Fang Li, Hongyan Ying, Huanwen Wu, Boju Pan, Zhaohui Zhu, Xiaoyuan Chen
Journal: Theranostics (2018)

Purpose: This study was to assess a gastrin-releasing peptide receptor (GRPR) and integrin αvβ3 dual targeting tracer 68 Ga-BBN-RGD for positron emission tomography (PET)/computed tomography (CT) imaging of breast cancer and metastasis.Materials and Methods: Twenty-two female patients were recruited either with suspected breast cancer on screening mammography (n = 16) or underwent breast cancer radical mastectomy (n = 6).All the 22 patients underwent PET/CT at 30-45 min after intravenous injection of 68 Ga-BBN-RGD.Eleven out of 22 patients also accepted 68 Ga-BBN PET/CT within 2 weeks for comparison.A final diagnosis was made based on the histopathologic examination of surgical excision or biopsy.Results: Both the primary cancer and metastases showed positive 68 Ga-BBN-RGD accumulation.The T/B ratios of 68 Ga-BBN-RGD accumulation were 2.10 to 9.44 in primary cancer and 1.10 to 3.71 in axillary lymph node metastasis, 3.80 to 10.7 in distant lymph nodes, 2.70 to 5.35 in lung metastasis and 3.17 to 22.8 in bone metastasis, respectively.For primary lesions, the SUVmax from 68 Ga-BBN-RGD PET in ER positive group was higher than that in ER negative group (P < 0.01).For both primary and metastatic lesions, SUVmean quantified from 68 Ga-BBN-RGD PET correlated well with both GRPR expression and integrin αvβ3 expression. Conclusion:This study demonstrated significant uptake of a new type of dual integrin αvβ3 and GRPR targeting radiotracer in both the primary lesion and the metastases of breast cancer. 68Ga-BBN-RGD PET/CT may be of great value in discerning both primary breast cancers, axillary lymph node metastasis and distant metastases.
Patient Commentary: I was pregnant, in pain, and desperate when I chose acupuncture
Authors: Kumari Manickasamy
Journal: BMJ (2018)

Eighteen months ago I developed severe pelvic girdle pain when pregnant with my second child. I had this condition in my first pregnancy, when it was successfully managed with physiotherapy and manipulation. However, this time it was much more severe and did not respond to the same treatment.

I reduced physical activity, did daily core stability exercises, and wore a sacroiliac support belt, but my mobility deteriorated precipitously. Walking became so difficult I needed crutches and a wheelchair. Sitting and even lying for too long on either side was painful. I could no longer work and became practically housebound. My physiotherapist felt she could do no more for me. In desperation I saw two other therapists, but …
Teach junior doctors how to combat bullying, say surgeons
Authors: Abi Rimmer
Journal: BMJ (2017)

Junior doctors in foundation training should receive compulsory training on how to challenge bullying behaviour, the Royal College of Surgeons of Edinburgh (RCSEd) has said.

As part its #LetsRemoveIt campaign against bullying and undermining, the college called on deaneries, Health Education England, and NHS Education for Scotland to introduce relevant compulsory training for foundation year doctors. This training would embed culture change, the college said, to “encourage people to challenge poor behaviour and …
“No chance at all” industrial action will bring about further pension negotiations
Authors: Helen Jaques
Journal: BMJ (2012)

There is “no chance at all” that the industrial action planned this month will result in reopening of negotiations on reform of the NHS pension scheme the secretary of state for health Andrew Lansley has warned the BMA.

In a letter to the BMA, he says that the Heads of Agreement negotiated in December last year represents the best offer available for individuals in the NHS pension scheme.

The BMA has said that it still hopes the government will agree to “meaningful negotiations to find a fairer way forward.” 

“We have always made it clear that we are taking industrial action reluctantly and would far prefer not to take it at all,” said Hamish Meldrum, chairman of BMA council.

On 21 June doctors will take industrial action for the first time in almost 40 years to oppose changes to the …
Cut in pensions tax relief will hit “thousands” of doctors, says BMA
Authors: Helen Jaques
Journal: BMJ (2012)

The government’s plan to reduce the amount that people can put into their pensions without paying tax will affect “thousands” of UK doctors, and not just the highest earners, the BMA has warned.

In his autumn statement the chancellor of the exchequer, George Osborne, announced that the lifetime allowance for pensions savings would be cut from £1.5m to £1.25m from 2014-15 and that the annual allowance would be cut from £50 000 to £40 000. He said that this measure would affect only the wealthiest pension savers. 

Osborne said that 98% of people currently approaching retirement have a pension pot worth less than £1.25m and that …
Hero’s return
Authors: Alison Shepherd
Journal: BMJ (2018)

Douglas Miller/Getty Images

Roger Bannister is cheered by fellow trainees at St Mary’s Hospital in Paddington, on 7 May 1954—the day after becoming the first man to run a mile in under four minutes.

It’s an image that combines both lives of the world beating athlete who later became a renowned neurologist and who died last week, aged …
Irish doctors to strike over “dangerous” working hours
Authors: Helen Jaques
Journal: BMJ (2013)

Junior doctors in the Republic of Ireland are planning a day of strike action in hospitals this month in the latest escalation of a row with the government over “dangerously long” working hours.

The Irish Medical Organisation has called a one day national strike on 25 September, after 97% of the roughly 1000 non-consultant hospital doctors who voted in a ballot agreed to take industrial action up to and including strike action. The union plans to then hold one day strikes in at least one hospital in each region in the country every week from 30 September to force the Health Service Executive to deal with the issue of working hours, which the union says are currently “illegal and dangerously long.”

The executive has now referred …
GPs reject call for “intermediate grade” akin to hospital staff grade
Authors: Abi Rimmer
Journal: BMJ (2015)

GPs have rejected calls for an “intermediate grade qualification for GPs, similar to staff grade in hospitals.”

Delegates at the BMA’s conference of local medical committees (LMCs) in London on 21 May voted against a motion that proposed the creation of such a grade. It said that it would “allow a career path for GP registrars whose practice is safe but does not reach the standard required for the MRCGP [membership of the Royal College of General Practitioners] qualification, …
Working plan for the use of patient-reported outcome measures in adults with brain tumours: a Response Assessment in Neuro-Oncology (RANO) initiative
Authors: Linda Dirven, Terri S Armstrong, Jaishri O Blakeley, Paul D Brown, Robin Grant, Rakesh Jalali, Heather Leeper, Tito Mendoza, Lakshmi Nayak, Jaap C Reijneveld, Emilie Le Rhun, Tobias Walbert, Michael Weller, Patrick Y Wen, Martin J B Taphoorn
Journal: The Lancet Oncology (2018)
IMPACT OF BIOMARKERS ON SHORT-TERM RISK PREDICTION OF GLOBAL CARDIOVASCULAR EVENTS IN OLDER ADULTS: ATHEROSCLEROSIS RISK IN COMMUNITIES STUDY
Authors: Anum Saeed, Vijay Nambi, Wensheng Sun, Salim Virani, Anita Deswal, Ron Hoogeveen, Lynne Wagenknecht, George Taffet, Kunihiro Matsushita, Elizabeth Selvin, Josef Coresh, James de Lemos, Christie Ballantyne
Journal: Journal of the American College of Cardiology (2018)
Comments on Comorbidity in Lung Cancer: A Prospective Cohort Study of Self-Reported versus Register-Based Comorbidity
Authors: Saeid Safiri
Journal: Journal of Thoracic Oncology (2018)

I read enthusiastically and meticulously the study conducted by Sandfeld-Paulsen et al. that was published in Journal of Thoracic Oncology.1Sandfeld-Paulsen B. Meldgaard P. Aggerholm-Pedersen N. Comorbidity in lung cancer: a prospective cohort study of self-reported versus register-based comorbidity.J Thorac Oncol. 2018; 13: 54-62Abstract Full Text Full Text PDF PubMed Scopus (16) Google Scholar The study provided interesting results; however, there are some methodological concerns that need to be raised to avoid misinterpretation. First, the authors considered smoking status as a fixed confounder in the multivariable analysis; however, smoking status is a time-varying variable with values that change over time. It has been discovered that conventional statistical methods can introduce bias in the effect estimates when confounders are time dependent.2Mansournia M.A. Etminan M. Danaei G. et al.Handling time varying confounding in observational research.BMJ. 2017; 359: j4587Crossref PubMed Scopus (173) Google Scholar Here, the resulting estimates in the Sandfeld-Paulsen et al. study should be interpreted with caution. Second, the authors recruited into the study patients who were referred to Aarhus University Hospital. Here, it should be noted that the resulting estimates for the relationship between comorbidity and overall survival may have a degree of referral bias and selection bias. Third, the difference between hazard ratios for the relationship between comorbidity and overall survival was negligible.1Sandfeld-Paulsen B. Meldgaard P. Aggerholm-Pedersen N. Comorbidity in lung cancer: a prospective cohort study of self-reported versus register-based comorbidity.J Thorac Oncol. 2018; 13: 54-62Abstract Full Text Full Text PDF PubMed Scopus (16) Google Scholar As a general rule, it is expected that effect estimates in a univariable model change by at least 10% after adjusting confounders; otherwise, there is a degree of residual confounding in the resulting estimates.3Lee P.H. Burstyn I. Identification of confounder in epidemiologic data contaminated by measurement error in covariates.BMC Med Res Methodol. 2016; 16: 54Crossref PubMed Scopus (59) Google Scholar Comorbidity in Lung Cancer: A Prospective Cohort Study of Self-Reported versus Register-Based ComorbidityJournal of Thoracic OncologyVol. 13Issue 1PreviewComorbidity is a debated prognosticator in lung cancer. Results are conflicting, and the variety in study designs and inclusion criteria hampers direct comparison of available studies. So far, methods for generation of data on lung cancer comorbidity have attracted little attention. We evaluated whether self-reported comorbidity and register-based comorbidity are of comparable quality. Full-Text PDF Open Archive
I am a psychiatrist and I qualified in Pakistan in 1994. How can I train in the UK and where can I find more about training in psychiatry?
Authors: Sabina Dosani
Journal: BMJ (2005)

<b>www.bmjcareers.com/advicezone</b> Have a career or related problem that needs answering? Can9t find the right person to point you in the right direction? Log on to the Advice Zone for reliable medical careers advice. You can post a question or see if one of our 300 advisers has already answered a similar question. Here is a selection of questions and answers posted on the site.
Incidental Detection of Synchronous Lung Melanoma on 18F-FDG PET/CT in a Patient With Parotid Gland Myoepithelial Carcinoma
Authors: Ashwin Singh Parihar, Abhiram GA, Karan Sood, Rajeev Kumar Seam, Vijay Kaushal, Ashwani Sood, Nandita Kakkar, Bhagwant Rai Mittal
Journal: Clinical Nuclear Medicine (2018)

The detection of synchronous or metachronous malignancies is on the rise with the advent of whole-body F-FDG PET/CT. It has shown its utility in detecting second primary carcinoma in patients undergoing imaging for evaluation of primary carcinoma, influencing the management and overall survival. Primary malignant melanoma of the lung is an extremely rare entity, accounting for 0.01% of all lung tumors. It is an even rare occurrence as a synchronous malignancy. We present the case of a 33-year-old woman with primary parotid myoepithelial carcinoma and incidental detection of second primary malignant melanoma of lung during F-FDG PET/CT imaging.
Abstract 13808: Sympathetic Overactivation but Not Hyponatremia as Independent Predictor of Cardiovascular Events and Mortality in Patients With Chronic Heart Failure
Authors: Takashi Akabane, Shuji Joho, Ryuichi Ushijima, Hiroshi Inoue
Journal: Circulation (2014)

Introduction: Previous studies have shown that hyponatremia could predict poor outcome in patients with heart failure (HF). However, it remains unknown whether hyponatremia is associated with incre...
Impact of contemporary patterns of chemotherapy utilization on survival in patients with advanced cancer of the urinary tract: a Retrospective International Study of Invasive/Advanced Cancer of the Urothelium (RISC)
Authors: A. Bamias, K. Tzannis, L.C. Harshman, S.J. Crabb, Y.-N. Wong, S. Kumar Pal, U. De Giorgi, S. Ladoire, N. Agarwal, E.Y. Yu, G. Niegisch, A. Necchi, C.N. Sternberg, S. Srinivas, A. Alva, U. Vaishampayan, L. Cerbone, M. Liontos, J. Rosenberg, T. Powles, J. Bellmunt, M.D. Galsky
Journal: Annals of Oncology (2017)
How to succeed in ST3 general surgery national recruitment
Authors: Goher Rahbour, Katy Hogben
Journal: BMJ (2014)

The process for national recruitment into the third year of specialty training in general surgery requires considerable preparation. <b>Goher Rahbour</b>, who improved his rank from 347th in 2012 to 37th in 2013, and consultant surgeon <b>Katy Hogben</b> offer some advice for candidates
Structural tract alterations predict downstream tau accumulation in amyloid-positive older individuals
Authors: Heidi I. L. Jacobs, Trey Hedden, Aaron P. Schultz, Jorge Sepulcre, Rodrigo D. Perea, Rebecca E. Amariglio, Kathryn V. Papp, Dorene M. Rentz, Reisa A. Sperling, Keith A. Johnson
Journal: Nature Neuroscience (2018)
Advanced training skills modules in obstetrics and gynaecology
Authors: Abdelmageed Abdelrahman, Janet R Acheson
Journal: BMJ (2013)

Advanced training skills modules have been designed to ensure future consultants in obstetrics and gynaecology have the skills necessary to work in the specialty. <b>Abdelmageed Abdelrahman</b> and <b>Janet Acheson</b> look at the background to these modules and discuss what trainees need to consider when choosing modules
IMPACT OF INITIATION OF BALLOON PULMONARY ANGIOPLASTY PROGRAM ON REFERRAL OF PATIENTS WITH CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION TO SURGERY
Authors: Myriam Amsallem, Julien Guihaire, Jennifer Arthur Ataam, Lilia Lamrani, David Boulate, Sacha Mussot, Dominique Fabre, Yu Taniguchi, Francois Haddad, Olivier Sitbon, Xavier Jais, Marc Humbert, Gérald Simonneau, Olaf Mercier, Philippe Brenot, Elie Fadel
Journal: Journal of the American College of Cardiology (2018)
USING A 1:1:1 PROPENSITY SCORE MATCHED COHORT TO ANALYZE THE COMPARATIVE EFFECTIVENESS OF NEW ORAL ANTICOAGULANT THERAPY USED FOR STROKE PROPHYLAXIS IN NON-VALVULAR ATRIAL FIBRILLATION
Authors: Patrick Racsa, Brad Sutton, Daniel Cornett, Jeffrey Ellis
Journal: Journal of the American College of Cardiology (2018)
Are all biopsies created equal? comparison of extended sextant prostate biopsies performed with and without MRI-TRUS fusion biopsy system.
Authors: Graham R. Hale, Jonathan Bloom, Vikram Sabarwal, Samuel Gold, Kareem Rayn, Brad J. Wood, Baris Turkbey, Peter A. Pinto, Tyler Hwang
Journal: Journal of Clinical Oncology (2018)

117 Background: Extended sextant systematic prostate biopsies have the inherent risk of under-sampling prostate cancer. Fusion guided multiparametric magnetic resonance imaging (mpMRI) biopsies have been employed to better represent the disease and guide treatment. We sought to determine if due to heightened suspicion of cancer and/or visualization of mpMRI there were any discrepancies between systematic biopsies done with a Fusion System as compared to those done without (TRUS alone). Methods: From a prospectively collected database, we performed a review collecting age, race, clinical stage, PSA, and time until repeat systematic biopsy as part of fusion guided biopsy (IB). We also collected pathology results reported as Gleason Score (GS), for both the patients’ OB and our IB. Patients were stratified into groups based on time between OB and IB/fusion biopsy ( &lt; 6 months, &lt; 1 year and &lt; 2 years). Results: 69 patients with a previous OB underwent combined fusion and IB within our designated time intervals. Cancer detection rates between the OB and IB results were similar at 6 months, 1 year and 2 years (80 vs 90%, 87.5 vs 87.5% and 65 vs 69%). Detection rates of GS ≥ 3+4 were higher with IB within 12 months compared with IB from 12-24 months (72.7 vs 40.9%, p = 0.03 OR 3.85 (1.09-13.66). Of the patients who were upgraded (n = 24), 54.2% (n = 13) went from benign pathology to a diagnosis of prostate adenocarcinoma. Of all OB GS 3+3 (n = 31), 29% were restaged to higher risk disease on IB. Rates of IB upgrading were similar within 6 months, 1 year and 2 year, 40%, 33.33% and 31.91%). Patients who were upgraded on IB compared to those who were not upgraded were of similar age (67.0 ± 6.53 vs 66.50 ± 6.47), race (17.4% African-American vs 13%), PSA (7.60 ± 5.61 vs 7.50 ± 4.39) and prostate volume on MRI (51.30 ± 26.87 vs 59.26 ± 38.52). Conclusions: A systematic biopsy at our referral center during a mpMRI fusion biopsy was over 3.5 times more likely to detect GS ≥ 3+4 when done within 1 year of the outside biopsy. There continued to be a risk, 34.7% overall, of disease upgrading in all time periods. This research was supported by the Intramural Research Program of the National Cancer Institute, NIH
Diagnosis uPGrade—Advances in Pyoderma Gangrenosum
Authors: Benjamin H. Kaffenberger, John Trinidad
Journal: JAMA Dermatology (2018)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Dermatology HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Dermatology journal
The ophthalmologist who job swapped
Authors: Farihah Tariq
Journal: BMJ (2011)

Farihah Tariq talks to <b>Tim Lavy</b> about relocating continents for an entire year with his family to work at Comprehensive Community Based Rehabilitation in Tanzania (CCBRT), while his exchange partner, Richard Bowman, a fellow paediatric ophthalmologist from the overseas disability charity CBM, cared for his patients in Scotland
Better access to general practice is linked to higher QOF scores, finds analysis
Authors: Zosia Kmietowicz
Journal: BMJ (2012)

General practices could improve the quality of their care by taking heed of patient satisfaction surveys and clinical effectiveness outcomes together and comparing themselves with the best performers, a health services think tank has said.

An analysis by the King’s Fund looked at the association between the clinical quality of services provided in general practice and the experience of patients using those services by analysing data from the Quality and Outcomes Framework (QOF) and surveys of patients for 2010-11 in all …
Discovery of Selective Estrogen Receptor Covalent Antagonists for the Treatment of ER alphaWTand ER alphaMUTBreast Cancer.
Authors: X. Puyang, C. Furman, G.Z. Zheng, Z.J. Wu, D. Banka, K. Aithal, S. Agoulnik, D.M. Bolduc, S. Buonamici, B. Caleb, S. Das, S. Eckley, P. Fekkes, M.H. Hao, A. Hart, R. Houtman, S. Irwin, J.J. Joshi, C. Karr, A. Kim, N. Kumar, P. Kumar, G. Kuznetsov, W.G. Lai, N. Larsen, C. Mackenzie, L.A. Martin, D. Melchers, A. Moriarty, T.V. Nguyen, J. Norris, M. O'Shea, S. Pancholi, S. Prajapati, S. Rajagopalan, D.J. Reynolds, V. Rimkunas, N. Rioux, R. Ribas, A. Siu, S. Sivakumar, V. Subramanian, M. Thomas, F.H. Vaillancourt, J. Wang, S. Wardell, M.J. Wick, S. Yao, L. Yu, M. Warmuth, P.G. Smith, P. Zhu, M. Korpal
Journal: Cancer Discovery (2018)
Quotas may be needed to get more women surgeons, college president says
Authors: Abi Rimmer
Journal: BMJ (2016)

Quotas may be needed to increase the number of women working in surgery if other interventions fail, the president of the Royal College of Surgeons of England, Clare Marx, has said.

Speaking at the Inspiring Future Female Leaders conference in London on 28 June, Marx discussed the steps the college was taking to encourage more women into the …
UK launches first foray into massive open online courses
Authors: Tom Moberly
Journal: BMJ (2013)

With millions of students already signed up to massive open online courses (MOOCs), these social learning exercises look set to have a big effect on higher education across the globe. <b>Tom Moberly</b> speaks to Futurelearn’s Simon Nelson, the man leading the United Kingdom’s first inroads in this area, about the potential effect of MOOCS on medical education
Progress in the Management of Malignant Pleural Mesothelioma in 2017
Authors: Amanda J. McCambridge, Andrea Napolitano, Aaron S. Mansfield, Dean A. Fennell, Yoshitaka Sekido, Anna K. Nowak, Thanyanan Reungwetwattana, Weimin Mao, Harvey I. Pass, Michele Carbone, Haining Yang, Tobias Peikert
Journal: Journal of Thoracic Oncology (2018)