Proposed U.S. Funding Cuts Threaten Progress on Antimicrobial Resistance
Authors: Helen W. Boucher, Barbara E. Murray, William G. Powderly
Journal: Annals of Internal Medicine (2017)

Ideas and Opinions21 November 2017Proposed U.S. Funding Cuts Threaten Progress on Antimicrobial ResistanceHelen W. Boucher, MD, Barbara E. Murray, MD, and William G. Powderly, MDHelen W. Boucher, MDFrom Tufts Medical Center, Boston, Massachusetts; University of Texas Medical School at Houston, Houston, Texas, and Washington University in St. Louis, St. Louis, Missouri., Barbara E. Murray, MDFrom Tufts Medical Center, Boston, Massachusetts; University of Texas Medical School at Houston, Houston, Texas, and Washington University in St. Louis, St. Louis, Missouri., and William G. Powderly, MDFrom Tufts Medical Center, Boston, Massachusetts; University of Texas Medical School at Houston, Houston, Texas, and Washington University in St. Louis, St. Louis, Missouri.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/M17-1678 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Antimicrobial resistance (AMR) is an escalating public health crisis that kills patients, threatens national security, and reduces the safety of medical procedures essential to save and enhance lives. Many types of complex medical care can be complicated by serious infections and rely on the availability of safe, effective antimicrobial drugs. In the past 2 years, national and global leaders have united against this threat, making tangible progress. However, budget cuts of a historic magnitude proposed by the Trump administration now threaten to undo this progress, placing patients in grave danger.The Centers for Disease Control and Prevention (CDC) estimates that ...References1. Centers for Disease Control and Prevention. Antibiotic resistance threats in the United States, 2013. 2013. Accessed at www.cdc.gov/drugresistance/pdf/ar-threats-2013-508.pdf on 25 August 2016. Google Scholar2. Review on Antimicrobial Resistance. Tackling drug-resistant infections globally: final report and recommendations. May 2016. Accessed at http://amr-review.org/sites/default/files/160525_Final%20paper_with%20cover.pdf on 25 August 2016. Google Scholar3. Sharma A, Hill A, Kurbatova E, van der Walt M, Kvasnovsky C, Tupasi TE, et al; Global Preserving Effective TB Treatment Study Investigators. Estimating the future burden of multidrug-resistant and extensively drug-resistant tuberculosis in India, the Philippines, Russia, and South Africa: a mathematical modelling study. Lancet Infect Dis. 2017;17:707-15. [PMID: 28499828] doi:10.1016/S1473-3099(17)30247-5 CrossrefMedlineGoogle Scholar4. G20. G20 leaders' declaration: shaping an interconnected world. July 2017. Accessed at www.g20.org/gipfeldokumente/G20-leaders-declaration.pdf on 28 August 2017. Google Scholar5. World Health Organization. Antimicrobial resistance: report by the Secretariat. 10 April 2017. Accessed at http://apps.who.int/gb/ebwha/pdf_files/WHA70/A70_12-en.pdf on 11 June 2017. Google Scholar6. Chambers HF, Cross HR, Evans SR, Kreiswirth BN, Fowler VG; Antibacterial Resistance Leadership Group (ARLG). The Antibacterial Resistance Leadership Group: progress report and work in progress. Clin Infect Dis. 2017;64:S3-7. [PMID: 28350896] doi:10.1093/cid/ciw824 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Tufts Medical Center, Boston, Massachusetts; University of Texas Medical School at Houston, Houston, Texas, and Washington University in St. Louis, St. Louis, Missouri.Disclaimer: Drs. Boucher, Murray, and Powderly are the Treasurer, Past President, and President, respectively, of the Infectious Diseases Society of America.Acknowledgment: The authors thank Amanda Jezek, Vice President, Public Policy and Government Relations, Infectious Diseases Society of America, and her team for their tireless efforts in responding to the crisis of AMR and assistance in preparing this manuscript.Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M17-1678.Corresponding Author: Helen W. Boucher, MD, Division of Geographic Medicine and Infectious Diseases, Tufts Medical Center, 750 Washington Street, Box 238, Boston, MA 02111; e-mail, [email protected]org.Current Author Addresses: Dr. Boucher: Division of Geographic Medicine and Infectious Diseases, Tufts Medical Center, 750 Washington Street, Box 238, Boston, MA 02111.Dr. Murray: University of Texas Medical School at Houston, 6431 Fannin Street, MSB 2.112, Houston, TX 77030.Dr. Powderly: Washington University in St. Louis, 4523 Clayton Avenue, Campus Box 8051, St. Louis, MO 63110.Author Contributions: Conception and design: H.W. Boucher, B.E. Murray, W.G. Powderly.Drafting of the article: H.W. Boucher, W.G. Powderly.Critical revision of the article for important intellectual content: H.W. Boucher, B.E. Murray, W.G. Powderly.Final approval of the article: H.W. Boucher, B.E. Murray, W.G. Powderly.Administrative, technical, or logistic support: H.W. Boucher.This article was published at Annals.org on 5 September 2017. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPhotoinactivation of Staphylococci with 405 nm Light in a Trachea Model with Saliva Substitute at 37 °CAssociation of a Safety Program for Improving Antibiotic Use With Antibiotic Use and Hospital-Onset Clostridioides difficile Infection Rates Among US HospitalsThe Infectious Diseases Society of America's 10 × '20 Initiative (10 New Systemic Antibacterial Agents US Food and Drug Administration Approved by 2020): Is 20 × '20 a Possibility?The Current State of Antimicrobial Stewardship: Challenges, Successes, and Future Directions 21 November 2017Volume 167, Issue 10Page: 738-739KeywordsAntibiotic resistanceAntibioticsAntimicrobial resistanceAntimicrobialsDrugsGlobal healthInfectious diseasesPrevention, policy, and public healthResearch laboratoriesVaccines ePublished: 5 September 2017 Issue Published: 21 November 2017 Copyright & PermissionsCopyright © 2017 by American College of Physicians. 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