Integrating Treatment at the Intersection of Opioid Use Disorder and Infectious Disease Epidemics in Medical Settings: A Call for Action After a National Academies of Sciences, Engineering, and Medicine Workshop
Authors: Sandra A. Springer, P. Todd Korthuis, Carlos del Rio
Journal: Annals of Internal Medicine (2018)

Ideas and Opinions4 September 2018Integrating Treatment at the Intersection of Opioid Use Disorder and Infectious Disease Epidemics in Medical Settings: A Call for Action After a National Academies of Sciences, Engineering, and Medicine WorkshopSandra A. Springer, MD, P. Todd Korthuis, MD, MPH, and Carlos del Rio, MDSandra A. Springer, MDYale School of Medicine and Yale University School of Public Health, New Haven, Connecticut (S.A.S.), P. Todd Korthuis, MD, MPHOregon Health & Science University, Portland, Oregon (P.T.K.), and Carlos del Rio, MDEmory University School of Medicine, Atlanta, Georgia (C.D.)Author, Article, and Disclosure Informationhttps://doi.org/10.7326/M18-1203 Annals Author Insight Video - Carlos del Rio, MD In this video, Carlos del Rio, MD, offers additional insight into the article, "Integrating Treatment at the Intersection of Opioid Use Disorder and Infectious Disease Epidemics in Medical Settings." SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail As a result of the opioid use disorder (OUD) epidemic (1), new epidemics of hepatitis C virus (HCV) and HIV infection have arisen and hospitalizations for bacteremia, endocarditis, skin and soft tissue infections, and osteomyelitis have increased (2–4). Optimal treatment of these conditions is often impeded by untreated OUD resulting in long hospital stays, frequent readmissions due to lack of adherence to antibiotic regimens or reinfection, substantial morbidity, and a heavy financial toll on the health care system. Medical settings that manage such infections offer a potential means of engaging people in treatment of OUD; however, few providers and hospitals ...References1. Rudd RA, Seth P, David F, Scholl L. Increases in drug and opioid-involved overdose deaths—United States, 2010–2015. MMWR Morb Mortal Wkly Rep. 2016;65:1445-52. [PMID: 28033313] doi:10.15585/mmwr.mm655051e1 CrossrefMedlineGoogle Scholar2. Ronan MV, Herzig SJ. Hospitalizations related to opioid abuse/dependence and associated serious infections increased sharply, 2002–12. Health Aff (Millwood). 2016;35:832-7. [PMID: 27140989] doi:10.1377/hlthaff.2015.1424 CrossrefMedlineGoogle Scholar3. Zibbell JE, Asher AK, Patel RC, Kupronis B, Iqbal K, Ward JW, et al. Increases in acute hepatitis C virus infection related to a growing opioid epidemic and associated injection drug use, United States, 2004 to 2014. Am J Public Health. 2018;108:175-81. [PMID: 29267061] doi:10.2105/AJPH.2017.304132 CrossrefMedlineGoogle Scholar4. Conrad C, Bradley HM, Broz D, Buddha S, Chapman EL, Galang RR; Centers for Disease Control and Prevention (CDC). Community outbreak of HIV infection linked to injection drug use of oxymorphone—Indiana, 2015. MMWR Morb Mortal Wkly Rep. 2015;64:443-4. [PMID: 25928470] MedlineGoogle Scholar5. Madras BK. The surge of opioid use, addiction, and overdoses: responsibility and response of the US health care system. JAMA Psychiatry. 2017;74:441-2. [PMID: 28355456] doi:10.1001/jamapsychiatry.2017.0163 CrossrefMedlineGoogle Scholar6. Koh H. Community approaches to the opioid crisis. JAMA. 2015;314:1437-8. [PMID: 26461987] doi:10.1001/jama.2015.12346 CrossrefMedlineGoogle Scholar7. Crowley R, Kirschner N, Dunn AS, Bornstein SS; Health and Public Policy Committee of the American College of Physicians. Health and public policy to facilitate effective prevention and treatment of substance use disorders involving illicit and prescription drugs: an American College of Physicians position paper. Ann Intern Med. 2017;166:733-6. [PMID: 28346947]. doi:10.7326/M16-2953 LinkGoogle Scholar8. Infectious Diseases Society of America; HIV Medicine Association; Pediatric Infectious Diseases Society. Infectious Diseases and Opioid Use Disorder (OUD): Policy Issues and Recommendations. March 2018. Accessed at www.hivma.org/uploadedFiles/HIVMA/News_Announcements/ID and the Opioid Epidemic Policy Brief_3 19 2018 Updated.pdf on 19 June 2018. Google Scholar9. Kuehn B. NIH strategy to combat opioid crisis. JAMA. 2017;318:2418. [PMID: 29279912] doi:10.1001/jama.2017.19920 CrossrefMedlineGoogle Scholar10. Wickersham JA, Azar MM, Cannon CM, Altice FL, Springer SA. Validation of a brief measure of opioid dependence: the Rapid Opioid Dependence Screen (RODS). J Correct Health Care. 2015;21:12-26. [PMID: 25559628] doi:10.1177/1078345814557513 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Yale School of Medicine and Yale University School of Public Health, New Haven, Connecticut (S.A.S.)Oregon Health & Science University, Portland, Oregon (P.T.K.)Emory University School of Medicine, Atlanta, Georgia (C.D.)Disclaimer: This article reflects the views of the authors.Acknowledgment: The authors thank Kathleen Stratton, PhD, from the Board on Population Health and Public Health Practice, Health and Medicine Division within the National Academies of Sciences, Engineering, and Medicine, for organizing the workshop and serving as study director, as well as the other members of the Workshop Planning Committee. Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M18-1203.Corresponding Author: Sandra A. Springer, MD, Department of Internal Medicine, Section of Infectious Diseases, AIDS Program, Yale School of Medicine, 135 College Street, Suite 323, New Haven, CT 06510; e-mail, sandra.[email protected]edu.Current Author Addresses: Dr. Springer: Department of Internal Medicine, Section of Infectious Diseases, AIDS Program, Yale School of Medicine, 135 College Street, Suite 323, New Haven, CT 06510.Dr. Korthuis: Department of Medicine, Section of Addiction Medicine, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Mail Code L-475, Portland, OR 97239-3098.Dr. del Rio: Hubert Department of Global Health, Rollins School of Public Health and Department of Medicine, Emory University School of Medicine, 1518 Clifton Road NE, Room 7011, Atlanta, GA 30322.Author Contributions: Conception and design: S.A. Springer, P.T. Korthuis, C. Del Rio.Analysis and interpretation of the data: S.A. Springer, C. Del Rio.Drafting of the article: S.A. Springer, C. Del Rio.Critical revision of the article for important intellectual content: S.A. Springer, P.T. Korthuis, C. Del Rio.Final approval of the article: S.A. Springer, P.T. Korthuis, C. Del Rio.Administrative, technical, or logistic support: C. Del Rio.Collection and assembly of data: S.A. Springer, C. Del Rio.This article was published at Annals.org on 13 July 2018. PreviousarticleNextarticle Advertisement Annals Author Insight Video - Carlos del Rio, MD In this video, Carlos del Rio, MD, offers additional insight into the article, "Integrating Treatment at the Intersection of Opioid Use Disorder and Infectious Disease Epidemics in Medical Settings." FiguresReferencesRelatedDetailsSee AlsoActions to Integrate Treatment of Opioid and Infectious Disease Epidemics Sandra A. Springer , P. Todd Korthuis , and Carlos del Rio Actions to Integrate Treatment of Opioid and Infectious Disease Epidemics Simeon D. Kimmel , Raagini Jawa , Alexander Y. Walley , and Tamar F. 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Kimmel, MD, MA, Raagini Jawa, MD, MPH, Alexander Y. Walley, MD, MSc, and Tamar F. Barlam, MD, MScActions to Integrate Treatment of Opioid and Infectious Disease EpidemicsJoshua A. Barocas, MDPrevention of Prescription Opioid Misuse and Projected Overdose Deaths in the United StatesInjection Drug Use–Associated Infective EndocarditisClinical Characteristics and Factors Associated With Mortality in First-Episode Infective Endocarditis Among Persons Who Inject Drugs 4 September 2018Volume 169, Issue 5Page: 335-336KeywordsEndocarditisHIV infectionsHealth careHealth care providersHospitalizationsInfectious diseasesOpioid use disorderOpioidsPatientsPrevention, policy, and public health ePublished: 13 July 2018 Issue Published: 4 September 2018 Copyright & PermissionsCopyright © 2018 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...