Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases
Authors: Philip C. Haycock, Stephen Burgess, Aayah Nounu, Jie Zheng, George N. Okoli, Jack Bowden, Kaitlin Hazel Wade, Nicholas J. Timpson, David M. Evans, Peter Willeit, Abraham Aviv, Tom R. Gaunt, Gibran Hemani, Massimo Mangino, Hayley Patricia Ellis, Kathreena M. Kurian, Karen A. Pooley, Rosalind A. Eeles, Jeffrey E. Lee, Shenying Fang, Wei V. Chen, Matthew H. Law, Lisa M. Bowdler, Mark M. Iles, Qiong Yang, Bradford B. Worrall, Hugh Stephen Markus, Rayjean J. Hung, Chris I. Amos, Amanda B. Spurdle, Deborah J. Thompson, Tracy A. O’Mara, Brian Wolpin, Laufey Amundadottir, Rachael Stolzenberg-Solomon, Antonia Trichopoulou, N. Charlotte Onland-Moret, Eiliv Lund, Eric J. Duell, Federico Canzian, Gianluca Severi, Kim Overvad, Marc J. Gunter, Rosario Tumino, Ulrika Svenson, Andre van Rij, Annette F. Baas, Matthew J. Bown, Nilesh J. Samani, Femke N.G. van t’Hof, Gerard Tromp, Gregory T. Jones, Helena Kuivaniemi, James R. Elmore, Mattias Johansson, James Mckay, Ghislaine Scelo, Robert Carreras-Torres, Valerie Gaborieau, Paul Brennan, Paige M. Bracci, Rachel E. Neale, Sara H. Olson, Steven Gallinger, Donghui Li, Gloria M. Petersen, Harvey A. Risch, Alison P. Klein, Jiali Han, Christian C. Abnet, Neal D. Freedman, Philip R. Taylor, John M. Maris, Katja K. Aben, Lambertus A. Kiemeney, Sita H. Vermeulen, John K. Wiencke, Kyle M. Walsh, Margaret Wrensch, Terri Rice, Clare Turnbull, Kevin Litchfield, Lavinia Paternoster, Marie Standl, Gonçalo R. Abecasis, John Paul SanGiovanni, Yong Li, Vladan Mijatovic, Yadav Sapkota, Siew-Kee Low, Krina T. Zondervan, Grant W. Montgomery, Dale R. Nyholt, David A. van Heel, Karen Hunt, Dan E. Arking, Foram N. Ashar, Nona Sotoodehnia, Daniel Woo, Jonathan Rosand, Mary E. Comeau, W. Mark Brown, Edwin K. Silverman, John E. Hokanson, Michael H. Cho, Jennie Hui, Manuel A. Ferreira, Philip J. Thompson, Alanna C. Morrison, Janine F. Felix, Nicholas L. Smith, Angela M Christiano, Lynn Petukhova, Regina C. Betz, Xing Fan, Xuejun Zhang, Caihong Zhu, Carl D. Langefeld, Susan D. Thompson, Feijie Wang, Xu Lin, David A. Schwartz, Tasha Fingerlin, Jerome I. Rotter, Mary Frances Cotch, Richard A. Jensen, Matthias Munz, Henrik Dommisch, Arne S. Schaefer, Fang Han, Hanna M. Ollila, Ryan P. Hillary, Omar Albagha, Stuart H. Ralston, Chenjie Zeng, Wei Zheng, Xiao-Ou Shu, Andre Reis, Steffen Uebe, Ulrike Hüffmeier, Yoshiya Kawamura, Takeshi Otowa, Tsukasa Sasaki, Martin Lloyd Hibberd, Sonia Davila, Gang Xie, Katherine Siminovitch, Jin-Xin Bei, Yi-Xin Zeng, Asta Försti, Bowang Chen, Stefano Landi, Andre Franke, Annegret Fischer, David Ellinghaus, Carlos Flores, Imre Noth, Shwu-Fan Ma, Jia Nee Foo, Jianjun Liu, Jong-Won Kim, David G. Cox, Olivier Delattre, Olivier Mirabeau, Christine F. Skibola, Clara S. Tang, Merce Garcia-Barcelo, Kai-Ping Chang, Wen-Hui Su, Yu-Sun Chang, Nicholas G. Martin, Scott Gordon, Tracey D. Wade, Chaeyoung Lee, Michiaki Kubo, Pei-Chieng Cha, Yusuke Nakamura, Daniel Levy, Masayuki Kimura, Shih-Jen Hwang, Steven Hunt, Tim Spector, Nicole Soranzo, Ani W. Manichaikul, R. Graham Barr, Bratati Kahali, Elizabeth Speliotes, Laura M. Yerges-Armstrong, Ching-Yu Cheng, Jost B. Jonas, Tien Yin Wong, Isabella Fogh, Kuang Lin, John F. Powell, Kenneth Rice, Caroline L. Relton, Richard M. Martin, George Davey Smith
Journal: JAMA Oncology (2017)

The causal direction and magnitude of the association between telomere length and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility of observational studies to confounding and reverse causation.