tbuckley/cabot-search huggingface dataset:
Sphinctéroclasie par macrodilatation du sphincter d'Oddi dans la prise en charge des empierrements cholédociens
Authors: D Karsenti, A Charachon, P Cabanis, A Courillon-Mallet, F Cohen-Aknine, N Molinier, A Goharin, JM Ferraz, P Lepicard
Journal: Endoscopy (2009)

But: La prise en charge endoscopique des empierrements cholédociens impose habituellement une lithotritie mécanique, impliquant une durée prolongée de procédure et parfois de multiples CPRE. Le but de cette étude était d'évaluer la morbidité et l'efficacité (succès, nombre de procédures, nécessité d'une lithotritie associée) d'un traitement endoscopique associant à la sphinctérotomie une sphinctéroclasie par macrodilatation du sphincter d'Oddi (SMSO) préalable à l'extraction d'un empierrement cholédocien.
Getting by with a little help from our friends
Authors: Enoch Lambert, Daniel C. Dennett
Journal: Behavioral and Brain Sciences (2018)

We offer two kinds of constructive criticism in the spirit of support for Doris's socially scaffolded pluralism regarding agency. First: The skeptical force of potential "goofy influences" is not as straightforward as Doris argues. Second: Doris's positive theory must address more goofy influences due to social processes that appear to fall under his criteria for agency-promoting practices. Finally, we highlight "arms race" phenomena in Doris's social dynamics that invite closer attention in further development of his theory.
Long-term outcomes with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in peritoneal carcinomatosis from appendiceal cancer: An 18-year experience.
Authors: Carlos A. Munoz-Zuluaga, Armando Sardi, Michelle Sittig, Victoria Eskay, Carol Ann Nieroda, Farah El-Sharkawy, Arkadii Sipok, Vadim Gushchin
Journal: Journal of Clinical Oncology (2017)

4098 Background: Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) have become standard of care for patients with peritoneal carcinomatosis (PC) from appendiceal cancer (AC). We reviewed our experience and outcomes. Methods: A retrospective review of 614 CRS/HIPEC procedures from 1998-2016 was performed. Patient characteristics, surgical variables, and postoperative outcomes of first CRS/HIPEC were analyzed. Results: Two hundred ninety patients with PC from AC underwent 334 CRS/HIPEC’s. Median age at diagnosis and surgery was 52 (22-79) and 53 (23-81) years, respectively; 65% (187) were female. Prior surgical score was 0, 1, 2, and 3 in 20%, 38%, 37%, and 5%, respectively. Prior systemic chemotherapy was reported in 30% of patients. Median time from diagnosis to CRS/HIPEC was 4 months (0-182). Pre-operative tumor markers (CEA, CA-125, CA-19-9) were positive in 48% with one, two, and three positive markers in 21%, 15%, and 13% patients, respectively. Median Peritoneal Cancer Index was 29. Mitomycin-C was the HIPEC agent of choice. Mean operative time was 10 hours (R: 4-19) and median length of stay was 10 days (R: 4-93). Histology included 59% (171) peritoneal mucinous carcinomatosis (PMCA), 41% (119) disseminated peritoneal adenomucinosis (DPAM). Lymph nodes were positive in 47% PMCA. Complete cytoreduction rate was 87% (84% PMCA, 92% DPAM [p = 0.048]). Grade III-V complications occurred in 21%, with one 30-day mortality (0.3%). Overall, median progression-free survival (PFS) was 84 months with 5-year PFS of 56%. Median PFS was 43 months in PMCA and not reached in DPAM. Five year PFS was 40% PMCA and 82% DPAM (p &lt; 0.001). Median overall survival (MOS) was 139 months with 61% 5-year OS. MOS was 53 months in PMCA and not reached in DPAM. Five year OS was 47% PMCA and 85% DPAM (p &lt; 0.001). At 42-month median follow-up, 68% were alive (92 PMCA/103 DPAM) with 84% disease free (72 PMCA/92 DPAM), 28% died of disease (73 PMCA/7 DPAM). Conclusions: CRS/HIPEC is an effective treatment for patients with PC from AC providing meaningful long term survival in low and high grade tumors and should be considered the standard of care.
RETROSPECTIVE COMPARISON OF THE RESULTS OF PREOPERATIVE RADIAL EUS WITH POSTOPERATIVE HISTOLOGY OF NON-EPITHELIAL TUMORS OF THE UPPER DIGESTIVE TRACT
Authors: E Gorbachev, S Shapovalianz, R Plakhov, Z Galkova, S Budzinskiy, E Fedorov, E Ernazarov
Journal: Endoscopy (2018)

There is no doubt that without performing EUS nobody would remove submucosal tumors (SMT) of the upper digestive tract (UGIT), while the importance of preoperative EUS-FNA is still debatable. How accurate radial EUS in predicting the morphological structure of SMT in routine clinical practice?
DEVELOPMENT OF A NEW SCORE SYSTEM TO DETERMINE THE RISK OF DELAYED BLEEDING AFTER ENDOSCOPIC MUCOSAL RESECTION OF LARGE COLORECTAL LESIONS
Authors: E Albéniz Arbizu, M Fraile Gonzalez, A Zebenzuy Gimeno-García, C Guarner Argente, D Martinez-Ares, F Ramos Zabala, MA Álvarez Alvarez, A Herreros de Tejada Echanojauregui, E Valdivielso Cortazar, J de la Peña, J Cobian, C Jerusalen Gargallo Puyuelo, O Nogales Rincon, J Gabriel Martinez Cara, JC Espinos, A Repiso Ortega, M Pellise, M Rodriguez Tellez, PA Aguirre, F Alberca de las Parras, JE Carbo Perseguer, J Rodriguez Sanchez
Journal: Endoscopy (2018)

There are two predictive models published that estimate the risk of delayed bleeding (DB) after endoscopic mucosal resection (EMR) of large colorectal lesions, the Spanish Endoscopic Resection Group predictive model (GSEED-RE) and the Australian Colonic Endoscopic Resection model (ACER), but none of them has been subjected to external validation.
GENDER OF COLONOSCOPIST: TRENDS OF PATIENT PREFERENCE DURING THE LAST DECADE IN KOREA
Authors: ES Kim, JM Lee, G Min, SJ Choi, W Kim, SH Kim, JM Lee, HS Choi, B Keum, YT Jeen, HJ Chun, HS Lee, CD Kim
Journal: Endoscopy (2018)

Colonoscopy is an invasive and uncomfortable procedure, and patients may feel fear and embarrassment during examination. The number of female gastroenterologists has been increased and options for gender is also on the rise. The aims of our study were to assess the preferences for gender of their colonoscopist, especially focusing on changes of gender preference during decade.
SUCCESSFUL ERADICATION OF SESSILE COLORECTAL POLYPS WITH COMBINED USE OF ENDOSCOPIC MUCOSAL RESECTION WITH ARGON PLASMA COAGULATION OF THE REMNANTS
Authors: D Christodoulou, V Theopistos, I Mitselos, K Katsanos, G Baltayiannis, N Tzabouras
Journal: Endoscopy (2018)

Sessile colorectal polyps represent sometimes a real challenge for the endoscopist. While the aim is to resect them completely by means of endoscopic mucosal resection or dissection, there are cases this approach may be unsuccessful. In these cases the use of argon plasma coagulation for eradication of the polyp remnants is a questioned approach.
WHAT IS THE COST OF ENDOSCOPIC SUBMUCOSAL DISSECTION IN FRANCE? A PROSPECTIVE MEDICO-ECONOMIC STUDY
Authors: M Dahan, E Pauliat, R Legros, D Sautereau, P Carrier, A Tailleur, L Merle, S Lyvat-Yonnet, V Loustaud-Ratti, S Kerever, S Brischoux, J Jacques
Journal: Endoscopy (2018)

The Health Insurance System has not delivered a listing of price quotation concerning Endoscopic submucosal dissection (ESD). The primary aim is to assess the costs and benefits of ESD. The secondary aim is to determine predictive factors for a benefit.
Delayed versus standard assessment for excision surgery in patients with Buruli ulcer in Benin: a randomised controlled trial
Authors: Akpeedje C Wadagni, Yves T Barogui, Roch C Johnson, Ghislain E Sopoh, Dissou Affolabi, Tjip S van der Werf, Janine de Zeeuw, Johanneke Kleinnijenhuis, Ymkje Stienstra
Journal: The Lancet Infectious Diseases (2018)
ASSESSMENT OF GASTRIC MUCOSA STRUCTURE WITH HIGH RESOLUTION MAGNIFYING ENDOSCOPY (HRME) AND FLEXIBLE SPECTRAL IMAGING COLOR ENHANCEMENT (FICE)
Authors: O Binicier, O Topalak
Journal: Endoscopy (2018)

Microstructure and the vascularity of the superficial gastric mucosa have been evaluated more clearly with HRME and digital chromoendoscopy methods which have been used in recent years. Structural changes in the gastric mucosa is known to be closely associated with intestinal metaplasia, atrophy, Helicobacter Pylori (H. Pylori) and chronic inflammation. The purpose of this study is to investigate the efficacy of the FICE added on HRME in evaluation of structural changes in the gastric mucosa.
A systematic review to explore the feasibility of a behavioural sleep intervention for insomnia in children with neurodevelopmental disorders: A transdiagnostic approach
Authors: Gabrielle Rigney, Nicole S. Ali, Penny V. Corkum, Cary A. Brown, Evelyn Constantin, Roger Godbout, Ana Hanlon-Dearman, Osman Ipsiroglu, Graham J. Reid, Sarah Shea, Isabel M. Smith, Hendrik F.M. Van der Loos, Shelly K. Weiss
Journal: Sleep Medicine Reviews (2018)
Endoscopic ultrasound-guided fine needle aspiration of solid masses: histologic and immunohistochemical evaluation
Authors: Lee Chang Hoon
Journal: Endoscopy (2011)

Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) has been widely demonstrated to be a useful to diagnose lesions adjacent to the gastrointestinal tract, especially around peripancreatic area. Immunohistochemical analysis of EUS-FNA specimens gives valuable information if combined with a cytopathologic analysis. Without on-site pathologist, histologic specimen not cytologic smear can be used for immunohistochemical analysis.
Blocking H1/H2 histamine receptors inhibits damage/fibrosis in Mdr2–/– mice and human cholangiocarcinoma tumorigenesis
Authors: Lindsey Kennedy, Laura Hargrove, Jennifer Demieville, Walker Karstens, Hannah Jones, Sharon DeMorrow, Fanyin Meng, Pietro Invernizzi, Francesca Bernuzzi, Gianfranco Alpini, Steven Smith, Austin Akers, Vik Meadows, Heather Francis
Journal: Hepatology (2018)

Primary sclerosing cholangitis (PSC) patients are at risk of developing cholangiocarcinoma (CCA). We have shown that (1) histamine increases biliary hyperplasia through H1/H2 histamine receptors (HRs) and (2) histamine levels increase and mast cells (MCs) infiltrate during PSC and CCA. We examined the effects of chronic treatment with H1/H2HR antagonists on PSC and CCA. Wild-type and multidrug-resistant knockout (Mdr2-/- ) mice were treated by osmotic minipumps with saline, mepyramine, or ranitidine (10 mg/kg body weight/day) or a combination of mepyramine/ranitidine for 4 weeks. Liver damage was assessed by hematoxylin and eosin. We evaluated (1) H1/H2HR expression, (2) MC presence, (3) L-histidine decarboxylase/histamine axis, (4) cholangiocyte proliferation/bile duct mass, and (5) fibrosis/hepatic stellate cell activation. Nu/nu mice were implanted with Mz-ChA-1 cells into the hind flanks and treated with saline, mepyramine, or ranitidine. Tumor growth was measured, and (1) H1/H2HR expression, (2) proliferation, (3) MC activation, (4) angiogenesis, and (5) epithelial-mesenchymal transition (EMT) were evaluated. In vitro, human hepatic stellate cells were evaluated for H1HR and H2HR expression. Cultured cholangiocytes and CCA lines were treated with saline, mepyramine, or ranitidine (25 μM) before evaluating proliferation, angiogenesis, EMT, and potential signaling mechanisms. H1/H2HR and MC presence increased in human PSC and CCA. In H1/H2HR antagonist (alone or in combination)-treated Mdr2-/- mice, liver and biliary damage and fibrosis decreased compared to saline treatment. H1/H2HR antagonists decreased tumor growth, serum histamine, angiogenesis, and EMT. In vitro, H1/H2HR blockers reduced biliary proliferation, and CCA cells had decreased proliferation, angiogenesis, EMT, and migration. Conclusion: Inhibition of H1/H2HR reverses PSC-associated damage and decreases CCA growth, angiogenesis, and EMT; because PSC patients are at risk of developing CCA, using HR blockers may be therapeutic for these diseases. (Hepatology 2018).
Colonoscopic perforations in the English National Health Service Bowel Cancer Screening Programme
Authors: Edmund Derbyshire, Pali Hungin, Claire Nickerson, Matthew Rutter
Journal: Endoscopy (2018)

Abstract Background Perforation is the most serious adverse event associated with colonoscopy. In this study of data from the English National Health Service Bowel Cancer Screening Programme, we aimed to describe the presentation and management of perforations, and to determine factors associated with poorer outcomes post-perforation. Methods The medical records of patients with a perforation following the national screening colonoscopy were retrospectively examined. All colonoscopies performed from 02/08/2006 to 13/03/2014 were studied. Bowel Cancer Screening Centres across England were contacted and asked to complete a detailed dataset relating to perforation presentation, management, and outcome. Results 263 129 colonoscopies were analyzed, and the rate of perforation was 0.06 %. Complete data were reviewed for 117 perforations: 70.1 % of perforations (82/117) occurred during therapeutic colonoscopies; 54.9 % (62/113) of patients with perforations who were admitted to hospital and in whom data were complete underwent surgery; 26.1 % (30/115) of hospitalized patients left the hospital with a stoma and 19.1 % (22/115) developed post-perforation morbidity. Perforations not detected during colonoscopy were significantly more likely to require surgery (P = 0.03). Diagnostic perforations were significantly more likely to require surgery (P = 0.002) and were associated with higher rates of post-perforation morbidity (P = 0.01). At presentation, the presence of abdominal pain (P = 0.01), a pulse rate &gt; 100 beats per minute (P = 0.049), and a respiratory rate &gt; 20 breaths per minute (P = 0.01) were significantly associated with the patient having surgery. Conclusions This is the largest retrospective observational case series in Europe to describe post-perforation presentation, management, and outcomes. We have confirmed that perforation leads to surgical intervention, stoma formation, and post-perforation morbidity. Perforations not recognized during the colonoscopy were significantly more likely to require surgery. Diagnostic perforations were at greater risk of requiring surgery and developing post-perforation morbidity.
Long-term evaluation of physical improvement and survival of autologous stem cell transplantation in POEMS syndrome
Authors: Chikako Ohwada, Emiko Sakaida, Chika Kawajiri-Manako, Yuhei Nagao, Nagisa Oshima-Hasegawa, Emi Togasaki, Tomoya Muto, Shokichi Tsukamoto, Shio Mitsukawa, Yusuke Takeda, Naoya Mimura, Masahiro Takeuchi, Naomi Shimizu, Sonoko Misawa, Tohru Iseki, Satoshi Kuwabara, Chiaki Nakaseko
Journal: Blood (2018)
ENDOSCOPIC ULTRASOUND IN BILIAR ACUTE PANCREATITIS. WHEN BEFORE ERCP
Authors: F Santos, B Moreira, L Citores, A Germade, S Maestro, R Madrigal, J Barcenilla, A Pérez
Journal: Endoscopy (2018)

The most frequent cause of acute pancreatitis is a biliary origin due to the passage of gallstones through the common bile duct.
Efficacy and costs of telehealth for the management of COPD: the PROMETE II trial
Authors: Julio Ancochea, Francisco García-Río, Emma Vázquez-Espinosa, Ascensión Hernando-Sanz, Luis López-Yepes, Raúl Galera-Martínez, Germán Peces-Barba, Maria Teresa Pérez-Warnisher, Gonzalo Segrelles-Calvo, Celia Zamarro, Pablo González-Ponce, M. Inmaculata Ramos, Jose Ignacio Conforto, Syed Jafri, Joan B. Soriano
Journal: European Respiratory Journal (2018)

Chronic obstructive pulmonary disease (COPD) is a significant and largely underdiagnosed cause of morbidity and mortality worldwide [1]. More long-term survivors with advanced disease have led to an ageing COPD population profile with an increased level of acute exacerbations, hospitalisations and polymorbidity [2]. In the PROMETE II trial, telehealth did not reduce COPD-related use of health services <http://ow.ly/KL7t30jotNb> We would like to thank the following staff from Fundación Teófilo Hernando (Madrid, Spain): Rocío Prieto, María Martínez, David Chong, Begoña Maestro and Arturo García. We would also especially like to thank all the participating patients and their families.
Incidence et complications de l'infundibulotomie lors des cholangiografies rétrogrades endoscopiques: étude prospective chez 151 malades
Authors: B Filloux, L Zgarni, F Cessot, JC Letard, D Sautereau, T Barrioz
Journal: Endoscopy (2009)

Introduction: L'infundibulotomie facilite l'accès à la voie biliaire lors des cathétérismes rétrogrades (CPRE), mais ce geste est réputéà haut risque de complication. Dans notre expérience, malgré un recours assez fréquent à l'infundibulotomie, sa morbidité ne semble pas très différente de celle de la sphinctérotomie seule. Le but de l'étude a été d'évaluer de façon prospective, dans deux centres experts en endoscopie biliaire, l'incidence de l'infundibulotomie et sa morbidité.
ENDOSCOPIC SUBMUCOSAL DISSECTION (ESD) BY TRAINEES TUTORED BY EXPERTS: SHORT-TERM RESULTS
Authors: A Wagner, D Neureiter, A Ziachehabi, T Kiesslich, HP Allgaier, G Kleber, K Heiler, D Plamenig, P Friesenbicher, M Lutz, H Seifert, M Anzinger, T Uraoka, T Toyonaga, N Yahagi, T Oyama, F Berr
Journal: Endoscopy (2018)

Patients (n = 101; 73 [37 – 91] years old) with neoplasias (n = 120; 20 esophageal, 13 gastric, 15 duodenal, 72 colorectal) fulfilling Japanese criteria for en-bloc resection were referred with consent for tutored ESD to Salzburg. European endoscopists – with initial clinical ESD experience – partially or completely resected the lesions under supervision of one of the four Japanese experts in 17 tutoring sessions (each with a duration of 1 – 4 days, 24 active and 27 passive participants from 16 countries).
EXPERIENCE AND UTILITY OF OVERSTITCH ENDOSCOPIC SUTURING SYSTEM IN A PUBLIC HOSPITAL
Authors: L Urtasun Arlegui, A Campos Ruiz, I Ganchegui Aguirre, P Aranzabal Aguilar, AB Fernández Laso, I Gorroño Zamalloa, I Azagra de Miguel, M Álvarez Rubio, C Martinez Blazquez, A Orive Calzada
Journal: Endoscopy (2018)

The OverStitch™ Endoscopic Suturing System was approved by the FDA in 2008 to perform endoscopically transmural sutures and soft tissue approximation.
SPIRAL ENTEROSCOPY ROLE IN DIAGNOSING AND TREATMENT OF SMALL BOWELL VASCULAR LESIONS
Authors: T Atena Pop, O Mosteanu, M Tantau
Journal: Endoscopy (2018)

Management of small-bowel (SB) vascular lesions has undergone significant changes due to recent developments in enteroscopy. The aim was to assess the diagnostic and therapeutic yield of spiral enteroscopy (SE) in obscure gastro-intestinal bleeding (OGIB).
Prognostic impact of copeptin in pulmonary embolism: a multicentre validation study
Authors: Kristian Hellenkamp, Piotr Pruszczyk, David Jiménez, Anna Wyzgał, Deisy Barrios, Michał Ciurzyński, Raquel Morillo, Lukas Hobohm, Karsten Keller, Katarzyna Kurnicka, Maciej Kostrubiec, Rolf Wachter, Gerd Hasenfuß, Stavros Konstantinides, Mareike Lankeit
Journal: European Respiratory Journal (2018)

To externally validate the prognostic impact of copeptin, either alone or integrated in risk stratification models, in pulmonary embolism (PE), we performed a post hoc analysis of 843 normotensive PE patients prospectively included in three European cohorts. Within the first 30 days, 21 patients (2.5%, 95% CI 1.5–3.8) had an adverse outcome and 12 (1.4%, 95% CI 0.7–2.5) died due to PE. Patients with copeptin ≥24 pmol·L −1 had a 6.3-fold increased risk for an adverse outcome (95% CI 2.6–15.5, p&lt;0.001) and a 7.6-fold increased risk for PE-related death (95% CI 2.3–25.6, p=0.001). Risk classification according to the 2014 European Society of Cardiology (ESC) guideline algorithm identified 248 intermediate-high-risk patients (29.4%) with 5.6% (95% CI 3.1–9.3) at risk of adverse outcomes. A stepwise biomarker-based risk assessment strategy (based on high-sensitivity troponin T, N-terminal pro-brain natriuretic peptide and copeptin) identified 123 intermediate-high-risk patients (14.6%) with 8.9% (95% CI 4.5–15.4) at risk of adverse outcomes. The identification of patients at higher risk was even better when copeptin was measured on top of the 2014 ESC algorithm in intermediate-high-risk patients (adverse outcome OR 11.1, 95% CI 4.6–27.1, p&lt;0.001; and PE-related death OR 13.5, 95% CI 4.2–43.6, p&lt;0.001; highest risk group versus all other risk groups). This identified 85 patients (10.1%) with 12.9% (95% CI 6.6–22.0) at risk of adverse outcomes and 8.2% (95% CI 3.4–16.2) at risk of PE-related deaths. Copeptin improves risk stratification of normotensive PE patients, especially when identifying patients with an increased risk of an adverse outcome.
Questions About a Clinical Trial Evaluating the Addition of Cetuximab to Definitive Chemoradiation Therapy With Paclitaxel and Cisplatin for Patients With Esophageal Cancer—Reply
Authors: Mohan Suntharalingam, Kathryn Winter, David Ilson
Journal: JAMA Oncology (2018)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Oncology HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Oncology journal
Fréquence et circonstances de découverte coloscopique des adénomes avancés asymptomatiques
Authors: V Jouhet, A Michaud-Herbst, JC Letard, M Beauchant, P Ingrand
Journal: Endoscopy (2009)

Introduction: Les recommandations de l'ANAES (2004) précisent la place de la coloscopie dans la détection des néoplasies colorectales. La détection précoce de formes curables constitue un enjeu d'amélioration de leur pronostic. L'objectif était de déterminer la fréquence de découverte des néoplasies colorectales lors de l'examen coloscopique ainsi que les circonstances de cette découverte.