tbuckley/cabot-search huggingface dataset:
Expanding the National Health Service Corps Scholarship Program to General Surgery
Authors: Joshua Tierney, Kyla Terhune
Journal: JAMA Surgery (2017)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Surgery HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Surgery journal
The Rise of Altmetrics
Authors: Hannah R. Warren, Nicholas Raison, Prokar Dasgupta
Journal: JAMA (2017)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hyper-CVAD and Rituximab for De Novo Burkitt Lymphoma/Leukemia
Authors: Deborah A. Thomas, Hagop M Kantarjian, Stefan Faderl, William G. Wierda, Elias Jabbour, Guillermo Garcia-Manero, Alessandra Ferrajoli, Srdan Verstovsek, Jan A. Burger, Luis Fayad, Jorge E Romaguera, Rebecca Garris, Jorge E. Cortes, Susan O'Brien
Journal: Blood (2011)
Heavy Chain Ratio (HLCR) IgGκ/IgGλ or IgAκ/IgAλ: Experience and Clinical Implications In Multiple Myeloma at Diagnosis and During Disease Course
Authors: Efstathios Koulieris, Marie-Christine Kyrtsonis, Nikolitsa Kafassi, Dimitris Maltezas, Vassiliki Bartzis, Tatiana Tzenou, Maria Dimou, George Georgiou, Ladan Mirbahai, Panayiotis Panayiotidis, Arthur Bradwell, Stephen Harding
Journal: Blood (2010)
Evaluation of Possible Risk Factors for Avascular Necrosis of the Femoral head in patients with Sickle Cell Disease
Authors: Abdul Kareem Al-Momen, Tarek Owaidah, Nizar Naqshabandi, Rana Hasanato, Sri-Halima Cana, Abdul Qayum, Marwan Zamzami, Aamer Aleem
Journal: Blood (2010)
DEAH-Box Splicing Factor Gene, Prp16 Amplification in Acute Myeloid Leukemia.
Authors: Yupo Ma, Tammy Barnett, Li Chai, Jianchang Yang, Zaida Alipio, Lin Pei, Hesham M. Amin, Louis Fink, Chunhui Di, Hai Yan, David Ward
Journal: Blood (2006)
Significantly Shorter Telomeres in T-Cells of ZAP-70+/CD38+ Patients with Chronic Lymphocytic Leukemia (CLL): An Important Role of T-Cells in This Subgroup of CLL?.
Authors: Alexander Roeth, Dirk de Beer, Holger Nueckel, Ludger Sellmann, Ulrich Duehrsen, Jan Duerig, Gabriela M. Baerlocher
Journal: Blood (2007)
Chronic Lymphocytic Leukemia Cells Have Increased Expression of Cyclic Nucleotide Phosphodiesterase 7B, Which May Serve as Disease-Specific Therapeutic Target.
Authors: Lingzhi Zhang, Fiona Murray, Joan R. Kanter, Daisy Chou, Laura Rassenti, Thomas J. Kipps, Paul A. Insel
Journal: Blood (2006)
Sixty seconds on . . . antidepressants
Authors: Nigel Hawkes
Journal: BMJ (2017)

Cheer up. The claim that the third Monday in January is the year’s most depressing day (“Blue Monday”) was a clever wheeze dreamed up in 2005 to sell winter holidays.

Evidence from Canada indicates that major depressive episodes are commoner in the winter: 70% higher in January than August, for example.1 But suicide peaks in the spring, not the …
Time to Development of Treatment-Emergent Extramedullary and Osseous Plasmacytomas in the Era of Novel Agents: An Analysis of Upfront Regimens in Newly Diagnosed MM Incorporating Lenalidomide and Bortezomib
Authors: Cindy Varga, Jacob P. Laubach, Irene M. Ghobrial, Matthew Weinstock, Claudia E. Paba-Prada, Robert L. Schlossman, Nikhil Munshi, Wanling Xie, Edie A. Weller, Kenneth C. Anderson, Constantine S. Mitsiades, Paul G. Richardson
Journal: Blood (2014)
Reply to L. Del Mastro and A. Prat
Authors: Neelima Denduluri, Mark R. Somerfield, Andrea Eisen, Jamie N. Holloway, Arti Hurria, Tari A. King, Gary H. Lyman, Ann H. Partridge, Melinda L. Telli, Maureen E. Trudeau, Antonio C. Wolff
Journal: Journal of Clinical Oncology (2017)
Haploidentical Hematopoietic Stem Cell Transplantation in Pediatric Patients: Comparison of Early Post-Transplant Outcome According to in Vitro Depletion Method
Authors: Ho Joon Im, Kyung Nam Koh, Jin Kyung Suh, Eun Seok Choi, Seongsoo Jang, Chan-Jeoung Park, Jong Jin Seo
Journal: Blood (2014)
High Level of Pretransplant Leukemic Blasts and the Absence of Chronic Graft-Versus-Host Disease Provide Negative Effects on Clinical Outcome of Transplantation with Fludarabine-Busulfex Based Reduced Intensity Conditioning for Patients with the De Novo Myelodysplastic Syndrome According to WHO Criteria.
Authors: Seok-Goo Cho, Byung-Sik Cho, Yoo-Jin Kim, Sung-Yong Kim, Ki-Seong Eom, HeeJe Kim, Seok Lee, Chang-Ki Min, Dong-Wook Kim, Jong-Wook Lee, Woo-Sung Min, Chun-Choo Kim
Journal: Blood (2006)
Equipping doctors for global health challenges
Authors: Marisa Casanova Dias, Aula Abbara, Rosie Gilbert, May CI van Schalkwyk, Claire P Rees, Howard Ryland, Andrew JM Leather, Bhanu Williams, Nigel Crisp
Journal: Journal of the Royal Society of Medicine (2017)

M e di ci n e 1 1 0 (1) , p p .5-8. 1 0.
Knock-down of osteopontin expression through lentiviral-mediated RNA interference suppresses the proliferation and invasiveness of hepatocellular carcinoma
Authors: Bing-Sheng Sun, Qing-Hai Ye, Hai-Jing Sun, Hai-Jun Zhou, Hu-Liang Jia, Ning Ren, Lun-Xiu Qin
Journal: Cancer Research (2008)

AACR Annual Meeting-- Apr 12-16, 2008; San Diego, CA

1961 

In our previous study, osteopontin (OPN) was identified as one of the leading genes that promoting the metastasis of hepatocellular carcinoma (HCC). However, the mechanism by which OPN is involved in metastasis of HCC is not understood yet. In this study, RNA interference (RNAi) mediated by viral vectors, which could induce down-regulation in gene expression for a longer time, was applied to analyze the roles of OPN in the proliferation, invasion and metastasis of HCC. Three lentiviral vectors encoding microRNA (miRNA) against OPN, Len.OPNi-1, -2 and -3 were constructed and found to down-regulate the OPN expression by 62%, 78% and 95% respectively in HCCLM3 cells ell line which had a higher expression level of OPN and a higher metastatic potential. Consequently, of the expression levels of MMP-2 and uPA were significantly down-regulated which led to a markedly inhibition of invasion and metastasis of HCCLM3 cells ( P< 0.001),. Moreover, besides the inhibitory effect on the invasion and metastasis, Len.OPNi-3 could also suppress the in vitro proliferation and in vivo tumor growth ( P< 0.001), however, it had no significant effect on the proliferation of HepG2 and CCL13 cells which had no overexpression of OPN). Len.OPNi-3, rather than Len.OPNi-2, significantly suppressed the mitogen-activated protein kinase kinase/ extracellular signal-regulated kinase (MEK/ERK1/2) signaling pathway in HCCLM3 cells. The recombinant OPN was found to induce the translocation of NF-κB (p65) into the nucleus of HCC cells and triggered the activation of pro-MMP-2 and MEK/ERK/1/2. These suggest that OPN plays an important role in both the growth and metastasis of HCC, which have a different minimum threshold for the basal expression level of OPN. Lentiviral-mediated RNAi targeting OPN may be a useful strategy to control the HCCs with a high OPN expression.
Viral Detection: Lateral Flow Assay Based on Paper–Hydrogel Hybrid Material for Sensitive Point‐of‐Care Detection of Dengue Virus (Adv. Healthcare Mater. 1/2017)
Authors: Jane Ru Choi, Kar Wey Yong, Ruihua Tang, Yan Gong, Ting Wen, Hui Yang, Ang Li, Yook Chin Chia, Belinda Pingguan‐Murphy, Feng Xu
Journal: Advanced Healthcare Materials (2017)

A much simpler device-manufacturing and operation process for lateral flow assays is described by Belinda Pingguan-Murphy, Feng Xu, and co-workers in article 1600920. Incorporation of agarose hydrogel into the glass fiber shunt achieves optimum fluidic delays for sensitive detection of dengue virus without altering the geometry of pads or creating hydrophobic barriers.
Effects of a Novel Benzyl Styryl Sulfone Derivative ON 01910.Na On the Myelodysplastic Syndrome (MDS) Derived Clone in Patients Relapsing Following Response to Azacitidine (AzaC) Therapy.
Authors: Lewis R. Silverman, Rosalie Odchimar-Reissig, Shyamala C. Navada, Takao Ohnuma, Vesna Najfeld, Francois Wilhelm, E. Premkumar Reddy, James F Holland
Journal: Blood (2009)
Role of Sialic Acid for Platelet Lifespan and Function
Authors: Anne Louise Sørensen, Viktoria Rumjantseva, Sara Nayeb-Hashemi, Sunita Patel-Hett, Jennifer Richardson, Joseph Italiano, Henrik Clausen, John H. Hartwig, Hans H. Wandall, Karin M. Hoffmeister
Journal: Blood (2008)
Efficacy and Safety of Radotinib in Chronic Phase Chronic Myeloid Leukemia Patients with Resistance or Intolerance to BCR-ABL Tyrosine Kinase Inhibitors: Radotinib Phase 2 Clinical Trial
Authors: Sung-Hyun Kim, Hari Menon, Saengsuree Jootar, Tapan Saikia, Jae-Yong Kwak, Sang Kyun Sohn, Joon Seong Park, Hyeoung Joon Kim, Suk Joong Oh, Hawk Kim, Dae Young Zang, Sahee Park, He Aun Lee, Hye Lin Park, Seok Hun Woo, Hong Youb Kim, Gong Yeal Lee, Dae Jin Cho, Jae Soo Shin, Dong Yeon Kim, Dong-Wook Kim
Journal: Blood (2012)
Genomic infectious disease epidemiology in partially sampled and ongoing outbreaks
Authors: Xavier Didelot, Christophe Fraser, Jennifer Gardy, Caroline Colijn
Journal: Molecular Biology and Evolution (2016)

Genomic data are increasingly being used to understand infectious disease epidemiology. Isolates from a given outbreak are sequenced, and the patterns of shared variation are used to infer which isolates within the outbreak are most closely related to each other. Unfortunately, the phylogenetic trees typically used to represent this variation are not directly informative about who infected whom—a phylogenetic tree is not a transmission tree. However, a transmission tree can be inferred from a phylogeny while accounting for within-host genetic diversity by coloring the branches of a phylogeny according to which host those branches were in. Here we extend this approach and show that it can be applied to partially sampled and ongoing outbreaks. This requires computing the correct probability of an observed transmission tree and we herein demonstrate how to do this for a large class of epidemiological models. We also demonstrate how the branch coloring approach can incorporate a variable number of unique colors to represent unsampled intermediates in transmission chains. The resulting algorithm is a reversible jump Monte–Carlo Markov Chain, which we apply to both simulated data and real data from an outbreak of tuberculosis. By accounting for unsampled cases and an outbreak which may not have reached its end, our method is uniquely suited to use in a public health environment during real-time outbreak investigations. We implemented this transmission tree inference methodology in an R package called TransPhylo, which is freely available from https://github.com/xavierdidelot/TransPhylo.
Arsenic Trioxide (ATO) In the Consolidation Treatment of Newly Diagnosed APL - First Interim Analysis of a Randomized Trial (APL 2006) by the French Belgian Swiss APL Group
Authors: Lionel Ades, Emmanuel Raffoux, Sylvie Chevret, Arnaud Pigneux, Xavier Thomas, Dominique Bordessoule, Norbert Vey, Agnès Guerci, Thierry Lamy, Christian Récher, Beatrice Muller, Olivier Tournilhac, Cécile Pautas, Jean-Yves Cahn, Jacques Delaunay, Eric Deconinck, Bruno Quesnel, Stephane de Botton, Aspasia Stamatoullas, Christine Chomienne, Herve Dombret, Laurent Degos, Pierre Fenaux
Journal: Blood (2010)
Engraftment Syndrome (ES) After Reduced-Intensity Stem Cell Transplantation (RIST): ES May Have a Negative Impact on Survival In Standard-Risk Patients
Authors: Takeshi Maeda, Kimikazu Yakushijin, Yoshitaka Asakura, Nobuhiro Hiramoto, Saiko Kurosawa, Yutaro Kamiyama, Suguru Fukuhara, Niina Ueno, Sung-Won Kim, Shin-Ichiro Mori, Ryuji Tanosaki, Yuji Heike, Kensei Tobinai, Yoichi Takaue, Takahiro Fukuda
Journal: Blood (2010)
Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller
Authors: Natalia T. Freund, Haoqing Wang, Louise Scharf, Lilian Nogueira, Joshua A. Horwitz, Yotam Bar-On, Jovana Golijanin, Stuart A. Sievers, Devin Sok, Hui Cai, Julio C. Cesar Lorenzi, Ariel Halper-Stromberg, Ildiko Toth, Alicja Piechocka-Trocha, Harry B. Gristick, Marit J. van Gils, Rogier W. Sanders, Lai-Xi Wang, Michael S. Seaman, Dennis R. Burton, Anna Gazumyan, Bruce D. Walker, Anthony P. West, Pamela J. Bjorkman, Michel C. Nussenzweig
Journal: Science Translational Medicine (2017)

Three new potent neutralizing antibodies neutralize autologous HIV-1 strains and contribute to viral control in an HIV-1 controller.
Long-Term Continuing Second Complete Remission (CCR2) despite Allogeneic Stem Cell Transplantation in CR1: Results from the International Randomised Phase III Study Pediatric Relapsed AML 2001/01
Authors: G.J.L. Kaspers, M. Zimmermann, D. Reinhardt, B. Gibson, R. Tamminga, H. Armendariz, M. Dworzak, S. Ha, L. Hovi, A. Maschan, A. Baruchel, Y. Bertrand, B. Razzouk, C. Rizzari, P. Smisek, O. Smith, B. Stark, U. Creutzig
Journal: Blood (2008)
Veliparib (ABT-888), Bendamustine, and Rituximab (VBR) Is Well Tolerated and Efficacious in Patients with Lymphoma: Final Analysis of a Phase 1b Clinical Trial of VB and a Cohort Expansion of Vbr in Patients with B-Cell Lymphoma
Authors: Jacob D Soumerai, Andrew D Zelenetz, Craig H Moskowitz, Anas Younes, Maria Lia Palomba, Paul A Hamlin, Ariela Noy, Steven M Horwitz, Matthew J. Matasar, Alison J Moskowitz, Carol S Portlock, David J Straus, Alice Chen, Richard F Little, Fallon France, Juho Whang, Nishant Mishra, Christine Jarjies, John F Gerecitano
Journal: Blood (2015)
Neurocognitive Impairment Following Recovery from ADAMTS13-Deficient Thrombotic Thrombocytopenia Purpura (TTP).
Authors: Qurana F. Lewis, James G. Scott, Johanna A. Kremer Hovinga, Bernhard Lämmle, Deirdra R. Terrell, Sara K. Vesely, James N. George
Journal: Blood (2007)
Molecular Profiling of Myeloid Progenitor Cells in Multi-Mutated Advanced Systemic Mastocytosis Identifies KIT D816V As a Distinct and Late Event
Authors: Mohamad Jawhar, Juliana Schwaab, Susanne Schnittger, Karl Sotlar, Hans Peter Horny, Georgia Metzgeroth, Sven Schneider, Nadine Müller, Nicole Naumann, Christoph Walz, Torsten Haferlach, Peter Valent, Wolf-Karsten Hofmann, Nicholas C.P. Cross, Alice Fabarius, Andreas Reiter
Journal: Blood (2014)
UGT1A1 Gene Polymorphisms &amp; A(TA)nTAA Promoter Configurations in Omani Sickle Cell Disease Patients.
Authors: Salam AlKindi, Anil Pathare, Shoaib AlZadjali, Asem Al Ghazaly, Nadeem Nusrat, Jalil Ur Rehman, Hammad Khan, Muhammad I. Khan, Fehmida Zia, Vinodkumar Panjwani, Hamood Al Haddabi, Qamariya Al Abri, David Gravell, J. David Dennison
Journal: Blood (2007)
Glycovariant CD37 Small Modular Immuno-Pharmaceutical (TruADhanCe™ SMIP) Promotes Enhanced Natural Killer Cell Mediated Cytotoxicity against Primary Chronic Lymphocytic Leukemia Cells.
Authors: Sarwish Rafiq, Carolyn Cheney, Peter A Thompson, Tony Siadak, Paul Algate, Chuck Cerveny, John C. Byrd, Natarajan Muthusamy
Journal: Blood (2009)
Trends in antimicrobial susceptibility for azithromycin and ceftriaxone in Neisseria gonorrhoeae isolates in Amsterdam, the Netherlands, between 2012 and 2015
Authors: Carolien M Wind, Maarten F Schim van der Loeff, Alje P van Dam, Henry JC de Vries, Jannie J van der Helm
Journal: Eurosurveillance (2017)

Resistance of Neisseria gonorrhoeae to azithromycin and ceftriaxone has been increasing in the past years. This is of concern since the combination of these antimicrobials is recommended as the first-line treatment option in most guidelines. To analyse trends in antimicrobial resistance, we retrospectively selected all consultations with a positive N. gonorrhoeae culture at the sexually transmitted infection clinic, Amsterdam, the Netherlands, from January 2012 through September 2015. Minimum inhibitory concentrations (MICs) for azithromycin and ceftriaxone were analysed per year, and determinants associated with decreased susceptibility to azithromycin (MIC > 0.25 mg/L) or ceftriaxone (MIC > 0.032 mg/L) were assessed. Between 2012 and 2015 azithromycin resistance (MIC > 0.5 mg/L) was around 1.2%, the percentage of isolates with intermediate MICs (> 0.25 and ≤ 0.5 mg/L) increased from 3.7% in 2012, to 8.6% in 2015. Determinants associated with decreased azithromycin susceptibility were, for men who have sex with men (MSM), infections diagnosed in the year 2014, two infected sites, and HIV status (HIV; associated with less decreased susceptibility); for heterosexuals this was having ≥ 10 sex partners (in previous six months). Although no ceftriaxone resistance (MIC > 0.125 mg/L) was observed during the study period, the proportion of isolates with decreased ceftriaxone susceptibility increased from 3.6% in 2012, to 8.4% in 2015. Determinants associated with decreased ceftriaxone susceptibility were, for MSM, infections diagnosed in 2014, and pharyngeal infections; and for heterosexuals, infections diagnosed in 2014 or 2015, being of female sex, and having ≥ 10 sex partners. Continued decrease of azithromycin and ceftriaxone susceptibility will threaten future treatment of gonorrhoea. Therefore, new treatment strategies are warranted.
Translational Research From the Tropical Forest: Silvestrol, a Natural Product From the Plant Aglaia Foveolata inhibits the Expression of Tyrosine Kinases and Shows a Significant In Vivo Activity in Acute Myeloid Leukemia (AML)
Authors: Houda Alachkar, Ramasamy Santhanam, David M. Lucas, Sebastian Schwind, Christopher Hickey, Jiuxia Pang, Danilo Perrotti, Li Pan, A Douglas Kinghorn, Guido Marcucci, Michael R Grever
Journal: Blood (2011)
Use of immunomodulater mycobacterium w vaccine for palliative treatment in advanced &amp; incurable cancer patients
Authors: R. I. Dave, S. V. Shah, K. M. Patel, U. B. Tripathi, A. S. Kapadia, H. P. Panchal
Journal: Journal of Clinical Oncology (2005)

2592 Background Immuno-therapy for prevention and treatment of malignant disease is in experimental stage. Initial work for urinary bladder cancer, melanoma and lung cancer has raised a hope that improving immune mechanisum can be of use. Method A prospective study was conducted at Gujarat Cancer & Research Institute from December 2003 to December 2004 to assess effect of tuberculosis vaccine (Mw) on tumor size, symptoms, and quality of life in 100 patients of advanced cases of carcinoma. The inclusion criteria were positive biopsy of malignancy, measurable disease, all available established treatment have exhausted, no other proved anti cancer treatment is going on and disease has been confirmed to be incurable by team of oncologist with life expectancy more than two months. Intradermal 0.1ml Mw was administered once a week for 5 weeks. Patients were evaluated every week for effect on tumor, symptoms and quality of life. Patients were followed up for 2 months. Result 77 cases had complete follow up. Male/Female ratio was 44/33. Commonest site of primary was Head and Neck Tumors and histology was squamous cell carcinoma. Out of 77 patients, 27-showed partial response associated with symptomatic improvement. Pain relief and reduction in opioid analgesic requirement was also noted. It was significant in 21 cases. In 4 patients, with non-healing sinus and Fistula, healing was observed. Relief of dysphagia found in 2 cases. There was no systemic side effect seen. There was improvement in quality of life in all patients. Conclusion In terminally ill advanced cancer patient use of intradermal Mw is useful for tumor regression, improved clinical response. Mw was not associated with any untoward side effects. No significant financial relationships to disclose.
Identification of a New Functional HDAC Complex Composed by HDAC5, GATA1 and EKLF in Human Erythroid Cells
Authors: Lilian Varricchio, Carmela Dell'Aversana, Angela Nebbioso, Giovanni Migliaccio, Lucia Altucci, James J. Bieker, Anna Rita F Migliaccio
Journal: Blood (2012)
Gene Expression Profiling Differentiates Childhood Acute Lymphoblastic Leukemia in Down Syndrome Versus Non-Down Syndrome Patients.
Authors: Karen R. Rabin, Jinhua Wang, Anna Tsimelzon, Debra Morrison, Amos S. Gaikwad, Laura Hogan, Cassia L. Rye, Susan G. Hilsenbeck, Meenakshi Devidas, Nyla A. Heerema, Andrew J. Carroll, Giuseppe Basso, William L. Carroll, Andrea Pession, Deepa Bhojwani
Journal: Blood (2008)
Frequency analysis of QRS complex with bundle branch block in patients with and without sustained ventricular tachycardia.
Authors: Naoto Yoneda, Shigeki Itoh, Toshinori Fujimoto, Hiroyuki Kurogane, Yutaka Yoshida
Journal: Circulation (1993)

To distinguish patients with bundle branch block (BBB) and sustained ventricular tachycardia (s-VT) from patients with BBB but without s-VT, a frequency analysis of the QRS complex was performed in 71 patients. Frequency analysis of the QRS complex of patients with left bundle branch block (LBBB) showed that patients with s-VT had significantly larger areas and area ratios between 50 and 100 Hz in the X lead than patients without s-VT (area: -0.905±0.231 vs -1.195±0.286. area ratio: -0.783±0.230 vs -1.125±0.310; P<0.05). The area and area ratios from 100 to 200 Hz in the Z lead were also larger in patients with s-VT. The highest predictive accuracy using the area ratio from 50 to 100 Hz in the X lead was 86%, with a sensitivity and specificity of 83% and 88%, respectively. In cases with LBBB, time domain analysis showed no significant difference between patients with s-VT and those without s-VT. Frequency analysis of the QRS complex may be useful for distinguishing LBBB patients with s-VT from those without s-VT.
Long-Term Results of a Trial of Concurrent Chemotherapy and Escalating Doses of Radiation for Unresectable Non–Small Cell Lung Cancer: NCCTG N0028 (Alliance)
Authors: Steven E. Schild, Shauna L. Hillman, Angelina D. Tan, Helen J. Ross, William L. McGinnis, Yolanda A. Garces, David L. Graham, Alex A. Adjei, James R. Jett
Journal: Journal of Thoracic Oncology (2017)