tbuckley/cabot-search huggingface dataset:
Heterogeneity in tumour content and necrosis in primary lung cancers: Implications for molecular analysis
Authors: Felicia Goh, Edwina Duhig, Belinda Clarke, Andrew Dettrick, David Godbolt, Kayla Tran, Louise Franz, Jeremy Barr, Kylie Parsonson, Maria Martins, Morgan Davidson, Casey Wright, John De laat, Janet Shaw, Jennifer Martin, Brielle Parris, Eloise Shaw, Laura De Souza, Jane Tjahjadi, Marissa Daniels, Jill E. Larsen, Annalese Semmler, Rachel Stockwell, Santiyagu Savarimuthu, Vandana Relan, Krishna Sriram, Jennifer Campbell, Samuel Kim, Maxine Tan, Leanne Morrison, Kelly Chee, Emily Impey, Annalicia Vaughan, Sasha A. Rahman, Nick Chang, Morgan Windsor, Rishendran Naidoo, Kevin Matar, Robert Tam, Peter Cole, Ian A. Yang, Rayleen Bowman, Kwun Fong
Journal: Journal of Thoracic Oncology (2013)
Food Poisoning
Authors: K. F. Meyer
Journal: New England Journal of Medicine (1953)

IN the broadest sense, food poisoning includes all illnesses arising from the ingestion of food, — food contaminated with pathogenic bacteria or their products, with nematodes or fungi, with chemical poisons and with poisonous plants and food poisonous in itself, — illnesses with a complete range of symptoms and of a great variety of causes. Various groups for various reasons choose to limit the definition according to their interests and preferences. The term is limited by some to acute gastroenteritis caused by ingestion of food or drink containing either bacteria capable of initiating an acute inflammatory reaction of the alimentary . . .
The effect of low-cost maintenance medication on the rehospitalization of schizophrenic outpatients
Authors: J Cody, A M Robinson
Journal: American Journal of Psychiatry (1977)

In an effort to determine whether expense is a relevant factor when schizophrenic outpatients discontinue maintenance medication, the authors gave low-cost drugs to 44 subjects, while 46 control subjects paid the retail rate. The unexpected result was that the group receiving low-cost drugs had a significantly higher rate of rehospitalization. The authors suggest that monetary investment on the patient's part may be an important factor in successful drug maintenance.
Paradoxical intention in the treatment of chronic anorexia nervosa
Authors: L K Hsu, S Lieberman
Journal: American Journal of Psychiatry (1982)

Eight patients with chronic anorexia nervosa were treated by the authors with a paradoxical approach. At follow-up 2-4 years later four of the patients had maintained a normal weight (within 15% of average weight), and only one patient was at a very low weight. The authors found this encouraging but caution that this technique does not address the individual's personality difficulties, for it did not appear to have improved the patients' social and sexual functioning. They believe, however, that paradoxical intention is worthy of further study in treating chronic anorexia nervosa.
Cyclic Direct Radionuclide Cystography in the Diagnosis and Characterization of Vesicoureteral Reflux in Children and Adults
Authors: Adriana Iozzi Joaquim, Moacir Fernandes de Godoy, Emmanuel A Burdmann
Journal: Clinical Nuclear Medicine (2015)

To investigate the influence of cyclic direct radionuclide cystography (RNC) on the diagnosis of vesicoureteral reflux (VUR) in children and adults.A total of 362 examinations were performed in patients with a mean age of 15.8 ± 17.2 years (2 months to 76.4 years, 89.5% female). The examinations were divided into 3 groups of age: A, younger than 5 years; B, 5 years and younger than 14 years; and C, older than 14 years. Repeated cycles of bladder filling without removal of the catheter were performed.VUR was diagnosed in 21% of patients based on the first cycle, 5.5% in the second cycle, and 2.5% only in the third cycle. Most examinations showing VUR corresponded to grade II. Reflux occurred in only the filling phase in 10%, only the voiding phase in 27%, and both phases in 63% of patients. There was a higher incidence of reflux in groups A and B than group C after the first cycle. The second cycle was equally effective in diagnosing VUR in all 3 groups. In group A, the third cycle was more effective compared to the other groups.Performing a second and a third cycle in RNC yielded an additional VUR diagnosis of 35.7%, as compared to performing only 1 cycle. The second cycle showed efficacy in all the groups, whereas the third cycle diagnosed more VUR only in group A. These results confirmed the importance of performing additional cycles in RNC for VUR diagnosis, both in children and adults.
Diagnosis of posttraumatic stress disorder in Viet Nam veterans: preliminary findings
Authors: R M Atkinson, L F Sparr, A G Sheff, R A White, J T Fitzsimmons
Journal: American Journal of Psychiatry (1984)

Sixty-six Viet Nam veterans were evaluated for posttraumatic stress disorder. Several of the DSM-III criteria for the disorder, but no other clinical features, distinguished patients diagnosed as having the disorder from others. The findings tend to validate the DSM-III construct for this disorder.
THE TREATMENT OF TOXIC NODULAR GOITER WITH RADIOACTIVE IODINE: 10 YEARS' EXPERIENCE WITH 436 CASES
Authors: MILTON ELLER, SOLOMON SILVER, STEPHEN B. YOHALEM, ROBERT L. SEGAL
Journal: Annals of Internal Medicine (1960)

Excerpt Introduction In the 10-year period between 1945 and 1954, about 2,000 patients with hyperthyroidism were treated with radioactive iodine at the Thyroid Clinic of The Mount Sinai Hospital in...
PWE-001 A randomised controlled trial of colonoscopic "scope guide" caecal intubation accuracy
Authors: D Cruttenden-Wood, S Zeidan, JD Foster, GF Nash
Journal: Gut (2015)

<h3>Introduction</h3> The scope-guide is seen by many as indispensable for managing loop resolution during colonoscopy. What is unknown is whether the scope-guide configuration can accurately predict if the caecum has been intubated. <h3>Method</h3> 100 images of the scope-guide pattern, from consecutive colonoscopies, were compiled by an individual consultant endoscopist. None of the patients had colonic resections. Half of the photographs documented the scope guide pattern whilst in the caecum (confirmed by appendix orifice and ileocaecal valve) and the other half were taken in the right colon but not in caecum. Three assessors, with endoscopic experience, were blinded to the randomised anonymised images as asked to record if the image correlated to ‘caecal’ on ‘non-caecal’ intubation. <h3>Results</h3> The correct allocation to ‘caecum’ or ‘not caecum’ was recorded in 54% of cases. The assessors were no better at recognising images taken in or not in the caecum (54:54). The sensitivity and specificity were 54.6% and 54.0% respectively. The PPV and NPV was 54.3% and 54.3% respectively. <h3>Conclusion</h3> Although beneficial in loop resolution, the scope guide image in isolation cannot be relied on to predict caecal intubation. <h3>Disclosure of interest</h3> None Declared.
Characteristics of emergency services personnel related to peritraumatic dissociation during critical incident exposure
Authors: C R Marmar, D S Weiss, T J Metzler, K Delucchi
Journal: American Journal of Psychiatry (1996)

The aim of this study was to identify characteristics of emergency services personnel related to acute dissociative responses at the time of critical incident exposure, a phenomenon designated "peritraumatic dissociation."The authors studied 157 rescue workers who responded to the Nimitz Freeway collapse during the 1989 Loma Prieta earthquake in the San Francisco Bay Area as well as 201 rescue workers who were not involved in that disaster. Demographics, level of critical incident exposure, perceived threat at the time of exposure, personality attributes (assessed by the Hogan Personality Inventory), coping strategies (assessed by the Ways of Coping Questionnaire), and locus of control were related to subjects' scores on the Peritraumatic Dissociative Experiences Questionnaire.According to univariate tests, the subjects with clinically meaningful levels of peritraumatic dissociation were younger; reported greater exposure to critical incident stress; felt greater perceived threat; had lower scores on the adjustment, identify, ambition, and prudence scales of the Hogan Personality Inventory; had higher scores on measures of coping by means of escape-avoidance, self-control, and active problem solving; and had greater externality in locus of control. Linear modeling with multiple logistic regression analyses indicated that greater feelings of perceived threat, coping by means of escape-avoidance, and coping by means of self-control were associated with a greater likelihood of being in the peritraumatic dissociation group, above and beyond age and exposure to stress.Rescue workers who are shy, inhibited, uncertain about their identity, or reluctant to take leadership roles, who have global cognitive styles, who believe their fate is determined by factors beyond their control, and who cope with critical incident trauma by emotional suppression and wishful thinking are at higher risk for acute dissociative responses to trauma and subsequent posttraumatic stress disorder.
Attempt to Detect a Mammary Tumor-Agent in Strain C Mice by Estrogenic Stimulation
Authors: Howard B. Andervont
Journal: JNCI Journal of the National Cancer Institute (1950)

Attempt to Detect a Mammary Tumor-Agent in Strain C Mice by Estrogenic Stimulation Get access Howard B. Andervont Howard B. Andervont National Cancer Institute, National Institutes of Health, U. S. Public Health Service, Bethesda, Md. Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 11, Issue 1, August 1950, Pages 73–81, https://doi.org/10.1093/jnci/11.1.73 Published: 01 August 1950 Article history Received: 10 April 1950 Published: 01 August 1950
P0127 : Patient-reported health-related quality of life outcomes independently predict death, transplant, hospitalization and hepatic encephalopathy in cirrhosis
Authors: K. Patidar, L. Thacker, J. Wade, M. White, A. Unser, E. Gavis, J. Hovermale, R.K. Sterling, M. Fuchs, M.S. Siddiqui, S. Matherly, R.T. Stravitz, A. Sanyal, P. Puri, V. Luketic, J.S. Bajaj
Journal: Journal of Hepatology (2015)
CLINICAL VALUE OF THE PALMOMENTAL REFLEX
Authors: B AUGUST, R B MILLER
Journal: JAMA (1952)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
SAT0309 The Utility of Spot Urine Uric Acid to Creatinine Ratio for Predictor of 24-Hour Urine Uric Acid Excretion in Gouty Patients
Authors: J.-S. Song, S.T. Choi, E.-H. Park
Journal: Annals of the Rheumatic Diseases (2015)

<h3>Background</h3> Gout is an inflammatory disease resulted from hyperuricemia. The measurement of 24-hour urine uric acid excretion is important not only to evaluate the disease status but also to choose the kind of uric acid lowering agents. 24-hour urine collection, however, is cumbersome, inconvenient, and often unreliable because of errors in collection. The average person excretes approximately 1 g of creatinine per day, and a lot of studies showed that the spot urine protein to creatinine ratio was correlated with 24-hour urine protein excretion. <h3>Objectives</h3> In this study, we investigated the utility of the spot urine uric acid to creatinine ratio for predicting 24-hour urine uric acid excretion in gouty patients. <h3>Methods</h3> Fifty-one gouty patients without any use of uric acid lowering agents were enrolled in this study. The average age was 48.1±17.1 years old and 90.2% (46/51) were male patients. 24-hour urine collections of the patients were conducted to the evaluate uric acid excretion and renal function. Spot urine uric acid and creatinine specimens were obtained from all participants at the same day when 24-hour urine was collected. The creatinine clearance (CCr) was measured from the 24-hour urine collected sample, and chronic kidney disease was defined when their CCr level was below 60 ml/min/1.73m<sup>2</sup>. <h3>Results</h3> The mean of 24-hour uric acid excretion was 643.5±259.2 mg, and those of serum uric acid levels and CCr values were 7.45±1.35 mg/dl and 103.5±41.8 ml/min/1.73m<sup>2</sup>, respectively. Spot urine uric acid to creatinine ratio was significantly correlated with the absolute and log transformed 24-hour urinary uric acid values (γ =0.410, <i>p</i> =0.003; γ =0.610, <i>p</i> &lt;0.001, respectively). In the linear regression analysis, the amount of absolute 24-hour urine uric acid excretion was estimated by 0.799 x (spot urine uric acid to creatinine ratio) + 336.239 (R<sup>2</sup> =0.410, <i>p</i> =0.003). The correlation between spot urine uric acid to creatinine ratio and 24-hour urine uric acid excretion was also found in the patients with chronic kidney disease (γ =0.964, <i>p</i> &lt;0.001). <h3>Conclusions</h3> Spot urine uric acid to creatinine ratio showed well correlation with the absolute and log transformed 24-hour urine uric acid excretions. The spot urine uric acid to creatinine ratio could be a good predictor of 24-hour urine uric acid excretion in gouty patients. <h3>Disclosure of Interest</h3> None declared
Current and Evolving Methods to Visualize Biological Data in Cancer Research
Authors: Puey Ling Chia, Craig Gedye, Paul C. Boutros, Paul Wheatley-Price, Thomas John
Journal: JNCI Journal of the National Cancer Institute (2016)

Although the measurements of clinical outcomes for cancer treatments have become diverse and complex, there remains a need for clear, easily interpreted representations of patients' experiences. With oncology trials increasingly reporting non-time-to-event outcomes, data visualization has evolved to incorporate parameters such as responses to therapy, duration and degree of response, and novel representations of underlying tumor biology. We review both commonly used and newly developed methods to display outcomes in oncology, with a focus on those that have evolved to represent complex datasets.
Brief Communication: Enhancement of Tumor Growth and Metastases by Medroxyprogesterone Acetate in Transplanted Uterine Adenocarcinoma Cells of the Rat
Authors: S. Sekiya, A. Yano, H. Takamizawa
Journal: JNCI Journal of the National Cancer Institute (1974)

This study describes the effects of medroxyprogesterone acetate on tumor growth and metastases in transplanted uterine adenocarcinoma cells of the rat. High-and-low-tumorigenic cloned cells of Sprague-Dawley rat uterine adenocarcinoma originally induced by 7,12-dimethylbenz (alpha) anthracene in vivo were used. Both were derived from the same parent culture. They were cultured for more than 2 years and both retained almost the same transplantability. Survival rate of cell colonies in vitro was reduced in both lines after progesterone treatment of more than 8 mcg per ml. This reduction was dose dependent. About 1 million cells suspended in .2 ml culture medium were injected sc into the interscapular region of isologous newborn rats. At 5 weeks these rats were given .5 mg medroxyprogesterone acetate twice a week for 2 weeks. At 7 weeks they were killed. High-tumorigenic cells produced growing tumors in all newborn rats. About a third of these rats died of metastases during the 7-week observation period. Tumors produced by low-tumorigenic cells grew slowly and occasionally regressed without metastases to the lung. Tumors in female rats were larger than those in males. Enhancement of tumor growth and metastases by this progesterone compound was observed in rats inoculated with low-tumorigenic cells as compared to controls. The enhancement was not significant in tumors produced by high-tumorigenic cells. The progesterone may act immunosuppressively in vivo, or make alterations in environmental conditions of the tumors.
PET/CT and Bremsstrahlung Imaging After 90Y DOTANOC Therapy for Rectal Net With Liver Metastases
Authors: Ümmühan Abdülrezzak, Mustafa Kula, Ahmet Tutuş, Fikret Buyukkaya, Halit Karaca
Journal: Clinical Nuclear Medicine (2015)

Peptide receptor radionuclide therapy with Lu or Y is promising with successful results in somatostatin receptor-positive tumors. In all radiation therapies, knowledge of the radiation dose received by the target, and other organs in the body is essential to evaluate the risks and benefits of any procedure. We report a case of liver metastases from a rectal neuroendocrine tumor, which was treated with Y DOTANOC. Posttreatment whole-body planar images were acquired through Bremsstrahlung radiations of Y on a γ-camera, and thoracolumbar PET/CT images were acquired on PET.
Ifosfamide: let's not end the honeymoon too soon.
Authors: A Y Chang
Journal: Journal of Clinical Oncology (1995)

Article Tools Article Tools OPTIONS & TOOLS Export Citation Track Citation Add To Favorites Rights & Permissions COMPANION ARTICLES No companion articles ARTICLE CITATION DOI: 10.1200/JCO.1995.13.7.1824 Journal of Clinical Oncology - published online before print September 21, 2016 PMID: 7677853 Ifosfamide: let's not end the honeymoon too soon. A Y ChangxA Y ChangSearch for articles by this author https://doi.org/10.1200/JCO.1995.13.7.1824 PDF "Ifosfamide: let's not end the honeymoon too soon.." Journal of Clinical Oncology, 13(7), pp. 1824–1826© 1995 by American Society of Clinical Oncology
Which Mexican-Americans underutilize health services?
Authors: K B Wells, R L Hough, J M Golding, M A Burnam, M Karno
Journal: American Journal of Psychiatry (1987)

Data collected from the Los Angeles site of the National Institute of Mental Health Epidemiologic Catchment Area Program were used to examine the utilization of health services in a community population. Mexican-Americans, especially the less acculturated, had significantly lower rates of use of outpatient, but not inpatient, care than non-Hispanic whites. Differences were greater for mental than physical health care. Less acculturated Mexican-Americans made very little use of either mental health specialists or the human services sector (e.g., religious leaders). Among those with a recent psychiatric disorder, non-Hispanic whites were seven times more likely to use outpatient mental health services than the less acculturated Mexican-Americans.
Risk of nontuberculous mycobacterial pulmonary disease with obstructive lung disease
Authors: Theodore K. Marras, Michael A. Campitelli, Jeffrey C. Kwong, Hong Lu, Sarah K. Brode, Alex Marchand-Austin, Andrea S. Gershon, Frances B. Jamieson
Journal: European Respiratory Journal (2016)

Nontuberculous mycobacterial pulmonary disease (NTM-PD) is increasingly prevalent [1] and especially common in the elderly [2]. It is usually chronic, requiring complex therapy with suboptimal outcomes [3]. Risk factors for NTM-PD may be covert, presumably disordered mucociliary defences, or overt structural lung abnormalities. In one study, 56% of NTM-PD patients had unexplained nontuberculous mycobacteria (NTM) and among the rest with structural lung disease, chronic obstructive pulmonary disease (COPD) was the most common predisposing condition [4]. High incidence of NTM pulmonary disease in people with COPD and asthma (142 and 53 per 100 000 person-years) <http://ow.ly/2laN300kLOV> Datasets used in this study were linked using unique encoded identifiers and analysed at ICES. Parts of this material are based on data and information compiled and provided by the Canadian Institute for Health Information (CIHI). However, the analyses, conclusions, opinions and statement expressed herein are those of the author, and not necessarily those of CIHI.
Effects of previous episodes of influenza and vaccination in preventing laboratory-confirmed influenza in Navarre, Spain, 2013/14 season
Authors: Jesús Castilla, Ana Navascués, Mirian Fernández-Alonso, Gabriel Reina, Esther Albéniz, Francisco Pozo, Nerea Álvarez, Iván Martínez-Baz, Marcela Guevara, Manuel García-Cenoz, Fátima Irisarri, Itziar Casado, Carmen Ezpeleta
Journal: Eurosurveillance (2016)

We estimated whether previous episodes of influenza and trivalent influenza vaccination prevented laboratory-confirmed influenza in Navarre, Spain, in season 2013/14. Patients with medically-attended influenza-like illness (MA-ILI) in hospitals (n = 645) and primary healthcare (n = 525) were included. We compared 589 influenza cases and 581 negative controls. MA-ILI related to a specific virus subtype in the previous five seasons was defined as a laboratory-confirmed influenza infection with the same virus subtype or MA-ILI during weeks when more than 25% of swabs were positive for this subtype. Persons with previous MA-ILI had 30% (95% confidence interval (CI): -7 to 54) lower risk of MA-ILI, and those with previous MA-ILI related to A(H1N1)pdm09 or A(H3N2) virus, had a, respectively, 63% (95% CI: 16-84) and 65% (95% CI: 13-86) lower risk of new laboratory-confirmed influenza by the same subtype. Overall adjusted vaccine effectiveness in preventing laboratory-confirmed influenza was 31% (95% CI: 5-50): 45% (95% CI: 12-65) for A(H1N1)pdm09 and 20% (95% CI: -16 to 44) for A(H3N2). While a previous influenza episode induced high protection only against the same virus subtype, influenza vaccination provided low to moderate protection against all circulating subtypes. Influenza vaccine remains the main preventive option for high-risk populations.