Comparative Benefits and Harms of Antidepressant, Psychological, Complementary, and Exercise Treatments for Major Depression
Authors: &Eacute;va Rásky, Sylvia Groth
Journal: Annals of Internal Medicine (2016)

Letters20 September 2016Comparative Benefits and Harms of Antidepressant, Psychological, Complementary, and Exercise Treatments for Major Depression&Eacute;va Rásky, MD, MME and Sylvia Groth, MA&Eacute;va Rásky, MD, MMEFrom Institute of Social Medicine, Medical University Graz, Graz, Austria.Search for more papers by this author and Sylvia Groth, MAFrom Institute of Social Medicine, Medical University Graz, Graz, Austria.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/L16-0210 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Gartlehner and colleagues' evidence report (1) finely compares harms and benefits of 4 treatment options for major depression, a well-done and needed study. However, the limitation section does not include a note on possibly implicit sex and gender biases.Major depression is a disease with documented sex differences in incidence and in effects of antidepressants. Differences in use of antidepressants and psychological, complementary, and exercise treatment may be related to gender. Despite evidence that sex and gender matter to health outcomes, data and analysis related to these factors are frequently absent in systematic reviews (2).This absence ...References1. Gartlehner G, Gaynes BN, Amick HR, Asher GN, Morgan LC, Coker-Schwimmer E, et al. Comparative benefits and harms of antidepressant, psychological, complementary, and exercise treatments for major depression: an evidence report for a clinical practice guideline from the American College of Physicians. Ann Intern Med. 2016;164:331-41. [PMID: 26857743]. doi:10.7326/M15-1813 LinkGoogle Scholar2. Runnels V, Tudiver S, Doull M, Boscoe M. The challenges of including sex/gender analysis in systematic reviews: a qualitative survey. Syst Rev. 2014;3:33. [PMID: 24720875] doi:10.1186/2046-4053-3-33 CrossrefMedlineGoogle Scholar3. International Committee of Medical Journal Editors. Recommendations for the conduct, reporting, editing, and publication of scholarly work in medical journals. Updated December 2015. Accessed at www.icmje.org/icmje-recommendations.pdf on 6 March 2016. Google Scholar4. Heidari S, Babor TE, De Castro P, Tort S, Curno M. Sex and gender equity in research guidelines: rationale for the SAGER guidelines and recommended use. Res Integr Peer Rev. 2016;1:2. doi:10.1186/s41073-016-0007-6 CrossrefMedlineGoogle Scholar5. Moerman CJ, Deurenberg R, Haafkens JA. Locating sex-specific evidence on clinical questions in MEDLINE: a search filter for use on OvidSP. BMC Med Res Methodol. 2009;9:25. [PMID: 19366443] doi:10.1186/1471-2288-9-25 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Institute of Social Medicine, Medical University Graz, Graz, Austria.Disclosures: Authors have disclosed no conflicts of interest. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterest Forms.do?msNum=L16-0210. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoComparative Benefits and Harms of Antidepressant, Psychological, Complementary, and Exercise Treatments for Major Depression: An Evidence Report for a Clinical Practice Guideline From the American College of Physicians Gerald Gartlehner , Bradley N. Gaynes , Halle R. Amick , Gary N. Asher , Laura C. Morgan , Emmanuel Coker-Schwimmer , Catherine Forneris , Erin Boland , Linda J. Lux , Susan Gaylord , Carla Bann , Christiane Barbara Pierl , and Kathleen N. Lohr Comparative Benefits and Harms of Antidepressant, Psychological, Complementary, and Exercise Treatments for Major Depression Alain Braillon , Jérémy Fonseca Das Neves , and Francoise Taiebi Comparative Benefits and Harms of Antidepressant, Psychological, Complementary, and Exercise Treatments for Major Depression Gerald Gartlehner , Bradley N. Gaynes , Catherine Forneris , and Kathleen N. Lohr Metrics Cited bySex and gender matters 20 September 2016Volume 165, Issue 6Page: 452-453KeywordsConflicts of interestDisclosureExerciseFactor analysisGender discriminationHealth equityResearch quality assessmentSexual identitySystematic reviews ePublished: 20 September 2016 Issue Published: 20 September 2016 Copyright & PermissionsCopyright © 2016 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...