tbuckley/cabot-search huggingface dataset:
Nonfearful panic disorder in neurology patients validated by lactate challenge
Authors: J L Russell, M G Kushner, B D Beitman, K M Bartels
Journal: American Journal of Psychiatry (1991)

Nonfearful panic disorder meets the DSM-III-R criteria for panic disorder but is not associated with subjective fear and anxiety. The authors determined its prevalence in a group of neurology patients and assessed its diagnostic validity as a panic disorder subtype by evaluating the response of the patients with nonfearful panic disorder to sodium lactate and antipanic pharmacotherapy.The subjects were all neurology patients referred over 1 year to a university hospital's psychiatric consultation service because of negative medical workups for their symptoms (N = 48). Patients who met the DSM-III-R criteria for panic disorder but did not report subjective anxiety or fear during panic episodes were diagnosed as having nonfearful panic disorder. Afterward, each of those patients received a sodium lactate infusion and, 5 hours later, a sodium chloride infusion. They were then treated with antipanic medication and followed for at least 6 months.Of the 48 neurology patients referred for psychiatric evaluation, 11 (23%) met the criteria for panic disorder, and all 11 met the criteria for nonfearful panic disorder. All 11 responded positively to lactate but not to placebo, and they each experienced an at least 75% reduction in symptoms during the 6-month follow-up period. Detailed case reports of three of these patients are presented.These findings support the construct and predictive diagnostic validity of nonfearful panic disorder as a subtype of panic disorder and suggest that a lack of attention to this group leads to both the underestimation of the prevalence of panic disorder and to the withholding of potentially successful treatments for this group.
Access to alcohol and heart disease among patients in hospital: observational cohort study using differences in alcohol sales laws
Authors: Jonathan W Dukes, Thomas A Dewland, Eric Vittinghoff, Jeffrey E Olgin, Mark J Pletcher, Judith A Hahn, Rachel A Gladstone, Gregory M Marcus
Journal: BMJ (2016)

<b>Objective</b>&nbsp;To investigate the relation between alcohol consumption and heart disease by using differences in county level alcohol sales laws as a natural experiment. <b>Design</b>&nbsp;Observational cohort study using differences in alcohol sales laws. <b>Setting</b>&nbsp;Hospital based healthcare encounters in Texas, USA. <b>Population</b>&nbsp;1 106 968 patients aged 21 or older who were residents of "wet" (no alcohol restrictions) and "dry" (complete prohibition of alcohol sales) counties and admitted to hospital between 2005 and 2010, identified using the Texas Inpatient Research Data File. <b>Outcome measures</b>&nbsp;Prevalent and incident alcohol misuse and alcoholic liver disease were used for validation analyses. The main cardiovascular outcomes were atrial fibrillation, acute myocardial infarction, and congestive heart failure. <b>Results</b>&nbsp;Residents of wet counties had a greater prevalence and incidence of alcohol misuse and alcoholic liver disease. After multivariable adjustment, wet county residents had a greater prevalence (odds ratio 1.05, 95% confidence interval 1.01 to 1.09; P=0.007) and incidence (hazard ratio 1.07, 1.01 to 1.13; P=0.014) of atrial fibrillation, a lower prevalence (odds ratio 0.83, 0.79 to 0.87; P&lt;0.001) and incidence (hazard ratio 0.91, 0.87 to 0.99; P=0.019) of myocardial infarction, and a lower prevalence (odds ratio 0.87, 0.84 to 0.90; P&lt;0.001) of congestive heart failure. Conversion of counties from dry to wet resulted in statistically significantly higher rates of alcohol misuse, alcoholic liver disease, atrial fibrillation, and congestive heart failure, with no detectable difference in myocardial infarction. <b>Conclusions</b>&nbsp;Greater access to alcohol was associated with more atrial fibrillation and less myocardial infarction and congestive heart failure, although an increased risk of congestive heart failure was seen shortly after alcohol sales were liberalized.
Neoplasms in the C3H Strain and in F&lt;sub&gt;1&lt;/sub&gt; Hybrid Mice of Two Crosses Following Introduction of Extracts and Filtrates of Leukemic Tissues
Authors: L. W. Law, Thelma B. Dunn, Peter J. Boyle
Journal: JNCI Journal of the National Cancer Institute (1955)

Journal Article Neoplasms in the C3H Strain and in F1 Hybrid Mice of Two Crosses Following Introduction of Extracts and Filtrates of Leukemic Tissues Get access L. W. Law, L. W. Law Laboratories of Biology and Pathology, National Cancer Institute,2Bethesda, Md. Search for other works by this author on: Oxford Academic PubMed Google Scholar Thelma B. Dunn, Thelma B. Dunn Laboratories of Biology and Pathology, National Cancer Institute,2Bethesda, Md. Search for other works by this author on: Oxford Academic PubMed Google Scholar Peter J. Boyle Peter J. Boyle Laboratories of Biology and Pathology, National Cancer Institute,2Bethesda, Md. Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 16, Issue 2, October 1955, Pages 495–539, https://doi.org/10.1093/jnci/16.2.495 Published: 01 October 1955 Article history Received: 15 April 1955 Published: 01 October 1955
Cytologic and Functional Characterization of Single Cell Clones Isolated from the Krebs-2 and Ehrlich Ascites Tumors&lt;xref ref-type="fn" rid="FN1"&gt;2&lt;/xref&gt;
Authors: Hauschka, Theodore S., Levan, Albert
Journal: JNCI Journal of the National Cancer Institute (1958)

Journal Article Cytologic and Functional Characterization of Single Cell Clones Isolated from the Krebs-2 and Ehrlich Ascites Tumors Get access Theodore S. Hauschka, Theodore S. Hauschka Roswell Park Memorial Institute, Buffalo, New York, and Institute of Genetics, Lund University, Lund, Sweden Search for other works by this author on: Oxford Academic PubMed Google Scholar Albert Levan Albert Levan Roswell Park Memorial Institute, Buffalo, New York, and Institute of Genetics, Lund University, Lund, Sweden Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 21, Issue 1, July 1958, Pages 77–135, https://doi.org/10.1093/jnci/21.1.77 Published: 01 July 1958 Article history Received: 12 December 1957 Published: 01 July 1958
Colorimetric <i>TMPRSS2-ERG</i> Gene Fusion Detection in Prostate Cancer Urinary Samples via Recombinase Polymerase Amplification
Authors: Kevin M Koo, Eugene J H Wee, Matt Trau
Journal: Theranostics (2016)

TMPRSS2 (Exon 1)-ERG (Exon 4) is the most frequent gene fusion event in prostate cancer (PC), and is highly PC-specific unlike the current serum prostate specific antigen (PSA) biomarker. However, TMPRSS2-ERG levels are currently measured with quantitative reverse-transcription PCR (RT-qPCR) which is time-consuming and requires costly equipment, thus limiting its use in clinical diagnostics. Herein, we report a novel rapid, cost-efficient and minimal-equipment assay named "FusBLU" for detecting TMPRSS2-ERG gene fusions from urine. TMPRSS2-ERG mRNA was amplified by isothermal reverse transcription-recombinase polymerase amplification (RT-RPA), magnetically-isolated, and detected through horseradish peroxidase (HRP)-catalyzed colorimetric reaction. FusBLU was specific for TMPRSS2-ERG mRNA with a low visual detection limit of 10(5) copies. We also demonstrated assay readout versatility on 3 potentially useful platforms. The colorimetric readout was detectable by naked eye for a quick yes/no evaluation of gene fusion presence. On the other hand, a more quantitative TMPRSS2-ERG detection was achievable by absorbance/electrochemical measurements. FusBLU was successfully applied to 12 urinary samples and results were validated by gold-standard RT-qPCR. We also showed that sediment RNA was likely the main source of TMPRSS2-ERG mRNA in urinary samples. We believe that our assay is a potential clinical screening tool for PC and could also have wide applications for other disease-related fusion genes.
Saint Bleecker
Authors: M Therese Southgate
Journal: JAMA (2005)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
MB-31NEW ONSET HYDROCEPHALUS DURING CHEMORADIATION THERAPY FOR MEDULLOBLASTOMA IN A BOY WITH GLUTARIC ACIDURIA TYPE 1
Authors: Kristin Plichta, David Peters, Brian Dlouhy, Mariko Sato, Alvaro Serrano Russi, Arnold Menezes, John Buatti
Journal: Neuro-Oncology (2016)
Incidence and Risk Factors for Intensive Care Unit–related Post-traumatic Stress Disorder in Veterans and Civilians
Authors: Mayur B. Patel, James C. Jackson, Alessandro Morandi, Timothy D. Girard, Christopher G. Hughes, Jennifer L. Thompson, Amy L. Kiehl, Mark R. Elstad, Mitzi L. Wasserstein, Richard B. Goodman, Jean C. Beckham, Rameela Chandrasekhar, Robert S. Dittus, E. Wesley Ely, Pratik P. Pandharipande
Journal: American Journal of Respiratory and Critical Care Medicine (2016)

Rationale: The incidence and risk factors of post-traumatic stress disorder (PTSD) related to the intensive care unit (ICU) experience have not been reported in a mixed veteran and civilian cohort.Objectives: To describe the incidence and risk factors for ICU-related PTSD in veterans and civilians.Methods: This is a prospective, observational, multicenter cohort enrolling adult survivors of critical illness after respiratory failure and/or shock from three Veterans Affairs and one civilian hospital. After classifying those with/without preexisting PTSD (i.e., PTSD before hospitalization), we then assessed all subjects for ICU-related PTSD at 3 and 12 months post hospitalization.Measurements and Main Results: Of 255 survivors, 181 and 160 subjects were assessed for ICU-related PTSD at 3- and 12-month follow-up, respectively. A high probability of ICU-related PTSD was found in up to 10% of patients at either follow-up time point, whether assessed by PTSD Checklist Event-Specific Version (score ≥ 50) or item mapping using the Diagnostic and Statistical Manual of Mental Disorders-IV (DSM-IV). In the multivariable regression, preexisting PTSD was independently associated with ICU-related PTSD at both 3 and 12 months (P < 0.001), as was preexisting depression (P < 0.03), but veteran status was not a consistent independent risk factor for ICU-related PTSD (3-month P = 0.01, 12-month P = 0.48).Conclusions: This study found around 1 in 10 ICU survivors experienced ICU-related PTSD (i.e., PTSD anchored to their critical illness) in the year after hospitalization. Preexisting PTSD and depression were strongly associated with ICU-related PTSD.
Depressive episodes and dysphoria resulting from conjugal bereavement in a prospective community sample
Authors: M L Bruce, K Kim, P J Leaf, S Jacobs
Journal: American Journal of Psychiatry (1990)

Using three waves of interviews from the New Haven Epidemiologic Catchment Area Program, the authors contrast the extent and nature of depressive episodes and dysphoria between newly bereaved (N = 39) and married (N = 1,047) respondents age 45 and older. Bereavement greatly increased the risk of both conditions. This observation did not appear to be an artifact because psychosocial risk factors were similar for the bereaved and married groups. Bereavement increased the risk for a depressive episode more among respondents who reported no prior dysphoria than among those who did. Among those meeting criteria for depression, the bereaved reported symptoms similar to those of the married group except for significantly fewer reports of guilt.
Does the Computed Tomographic Scan Tell the Whole Story for Cervical Spine Clearance?
Authors: Olubode A. Olufajo, Ali Salim
Journal: JAMA Surgery (2016)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Surgery HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Surgery journal
Substitutions and deletions in the cytoplasmic domain of the phagocytic receptor Fc gamma RIIA: effect on receptor tyrosine phosphorylation and phagocytosis [published erratum appears in Blood 1994 Nov 1;84(9):3252]
Authors: MA Mitchell, MM Huang, P Chien, ZK Indik, XQ Pan, AD Schreiber
Journal: Blood (1994)
A controlled study of penfluridol in the treatment of chronic schizophrenia
Authors: Y D Lapierre
Journal: American Journal of Psychiatry (1978)

Twenty patients were treated with penfluridol and 21 with fluphenazine for a period of up to 1 year. Penfluridol, an oral neuroleptic administered weekly was as efficacious as fluphenazine administered twice daily and appeared to be superior to fluphenazine in improving emotional withdrawal and anergia. The low incidence of side effects and other signs of toxicity, coupled with an effective prophylactic activity, suggests that penfluridol is an important addition to our therapeutic armamentarium for the treatment of chronic schizophrenia.
Steroid Administration May Be Valuable in Herpes Zoster
Authors: F A ELLIOTT
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A Cost-Effectiveness Analysis of Nivolumab versus Docetaxel for Advanced Nonsquamous NSCLC Including PD-L1 Testing
Authors: Klazien Matter-Walstra, Matthias Schwenkglenks, Stefan Aebi, Konstantin Dedes, Joachim Diebold, Mario Pietrini, Dirk Klingbiel, Roger von Moos, Oliver Gautschi
Journal: Journal of Thoracic Oncology (2016)
Abstract 13135: Demographics, Clinical Risk Factors and Peripheral Vascular Disease Among 3.6 Million Adults
Authors: Jeffrey S Berger, Mark A Adelman, Thomas S Riles, Caron B Rockman
Journal: Circulation (2011)

Background: Peripheral vascular disease (PVD) is associated with significant morbidity and mortality. The precise relationship between age, sex, race, clinical cardiovascular risk factors and preva...
From nurture to network: examining links between perceptions of parenting received in childhood and social bonds in adulthood
Authors: G B Parker, E A Barrett, I B Hickie
Journal: American Journal of Psychiatry (1992)

The authors' goal was to consider the extent to which key characteristics of their parents influence children's later socialization in terms of social networks and intimate relationships and thus to examine whether there is evidence of such continuity.The authors reviewed the pertinent literature and then examined studies using a measure of key dimensions of the parenting received in childhood (the Parental Bonding Instrument) as well as measures of adult social networks.The literature review revealed evidence of links (more evident in women) between perceptions of having received uncaring parenting and deficiencies in diffuse social bonds, which could reflect a causal process, a general response bias, or methodological limitations. By contrast, studies using the Parental Bonding Instrument and a specific measure of adult intimate bonds failed to find links between perceptions of parenting received in childhood and the quality of current intimate relationships unless there was extreme deprivation of parental care; in that case, the current intimate relationship was more likely to be rated as uncaring.These findings refine the view that early socialization experiences shape and dictate interpersonal relationships in adulthood. Any deficiencies in parent-child relationships, except, perhaps, gross parental deprivation, appear capable of modification by a range of experiences (particularly subsequent interpersonal relationships).
TECHNIQUE FOR THE DIAGNOSIS OF UNDESCENDED TESTIS
Authors: R H KUNSTADTER
Journal: JAMA (1952)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Amount of calories retained after binge eating and vomiting
Authors: W H Kaye, T E Weltzin, L K Hsu, C W McConaha, B Bolton
Journal: American Journal of Psychiatry (1993)

While caloric consumption during binge eating has been measured, it is not known how many of the calories are retained in the gastrointestinal tract after vomiting. In 17 normal weight bulimic patients, there appeared to be a ceiling on the number of calories retained after vomiting. That is, whether or not bulimic patients had small (mean = 1,549 kcal, SD = 505) or large (mean = 3,530 kcal, SD = 438) binges, they retained similar amounts of kilocalories (mean = 1,128, SD = 497, versus mean = 1,209, SD = 574, respectively) after vomiting.
MB-15PILOT STUDY OF REDUCED-DOSE CRANIOSPINAL IRRADIATION (CSI) WITH CONCURRENT CARBOPLATIN AND VINCRISTINE IN HIGH RISK MEDULLOBLASTOMA AND PRIMITIVE NEURO-ECTODERMAL TUMORS (PNETs)
Authors: Jennifer Madden, Nick Foreman, Rajeev Vibhakar, Arthur Liu
Journal: Neuro-Oncology (2016)
Syndromic surveillance: the next phase of public health monitoring during the H1N1 influenza pandemic?
Authors: A J Elliot
Journal: Eurosurveillance (2009)

Preview this article: Syndromic surveillance: the next phase of public health monitoring during the H1N1 influenza pandemic?, Page 1 of 1 < Previous page | Next page > /docserver/preview/fulltext/eurosurveillance/14/44/art19391-en-1.gif
In this issue of The American Journal of Psychiatry
Authors: L D Butler, R E Duran, P Jasiukaitis, C Koopman, D Spiegel
Journal: American Journal of Psychiatry (1996)

The authors propose a diathesis-stress model to describe how pathological dissociation may arise from an interaction between innate hypnotizability and traumatic experience.To support the proposition that pathological dissociation may reflect autohypnotic process, the authors highlight clinical and research data indicating parallels between controlled hypnotic dissociative states and uncontrolled pathological dissociative symptoms and summarize evidence of hypnotizability in persons with psychiatric disorders that manifest these symptoms. The authors present this evidence by examining dissociative symptomatology in four psychological domains: perception, behavior and will, affect, and memory and identity. In addition, modern cognitive and neuropsychological models of dissociation are briefly reviewed.Several lines of evidence converge in support of the role of autohypnosis in pathological dissociation. There is considerable evidence that controlled formal hypnosis can produce a variety of dissociations of awareness and control that resemble many of the symptoms in uncontrolled pathological dissociative conditions; and it is possible to discern in dissociative pathology the features of absorption, dissociation, and suggestibility/automaticity that characterize formal hypnotic states. There is also accumulating evidence of high levels of hypnotic capacity in all groups with dissociative symptomatology that have been systematically assessed. In addition, the widespread and successful therapeutic use of hypnosis in the treatment of many dissociative symptoms and conditions (and the potential for hypnosis to induce dissociative symptomatology) also supports the assumption that hypnosis and pathological dissociation share an underlying process.High hypnotizability may be a diathesis for pathological dissociative states, particularly under conditions of acute traumatic stress.