THU0619-HPR Resistance Training in Patients with Psoriatic Arthritis Improves Function, Disease Activity and Quality of Life
Authors: D.R. Silva, F. Jennings, E. Moreira, J. Natour
Journal: Annals of the Rheumatic Diseases (2015)

<h3>Background</h3> Psoriatic arthritis (PSA) is a chronic inflammatory arthritis, defined as the association of inflammatory arthropathy and skin psoriasis. The literature is still very scarce with regard to non-pharmacological treatments for patients with PSA, specially physical exercise. <h3>Objectives</h3> The aim of this study was to assess the effectiveness of resistance training in improving functional capacity, muscle strength, quality of life and disease activity in patients with PSA <h3>Methods</h3> Forty-one patients aged between 18 and 65 years with diagnosis of psoriatic arthritis were selected to this study.,The patients were randomized into two groups: intervention group and control group. The intervention group (IG) underwent resistance exercise twice a week, for twelve weeks. The control group remained on the waiting list with the conventional drug therapy. The outcome measurements were: BASFI and HAQ-S for functional capacity, one maximum-repetition test (1RM) for strength (1RM), SF-36 questionnaire for general quality of life; and BASDAI and DAS-28 for disease activity. The evaluations were done by a blinded evaluator at baseline (T0), 6 weeks (T6) and 12 weeks (T12) after the beginning of the study. <h3>Results</h3> At baseline the groups were homogeneous regarding clinical and demographic characteristics. The IG significantly improved functional capacity measured by HAQ-S and disease activity measured by BASDAI, compared to CG, at week 12. Regarding quality of life, the IG improved the domains “pain” and “general health status” compared to CG. (p&lt;0.05). There was improvement in muscular strength in almost all exercises in IG, except in the exercise for biceps. In the CG, the improvement in strength was observed only on “crucifix” (bilateral) and “leg extension” (bilateral) exercises. However, there was statistical differences between groups only on exercise “leg extension” (right side) in favor of IG. <h3>Conclusions</h3> Resistance training is effective in improving physical capacity, disease activity and quality of life of patients with psoriatic arthritis. The clinical improvements were not coupled to significant changes in muscular strength. <h3>References</h3> Moll JHM, Wright V. Psoriatic arthritis. Semin Arthritis Rheum, 3: 55.1973. J Zochling, D van der Heijde, R Burgos-Vargas, E Collantes, J C Davis, Jr, B Dijkmans, M Dougados, P Géher, R D Inman, M A Khan, T K Kvien, M Leirisalo-Repo, I Olivieri, K Pavelka, J Sieper, G Stucki, R D Sturrock, S van der Linden, D Wendling, H Böhm, B J van Royen, and J Braun. ASAS/EULAR recommendations for the management of ankylosing spondylitis. Ann Rheum Dis. Apr 2006. Lubrano E, Spadaro A, Marchesoni A, Olivieri I, Scarpa R, D9Angelo S. et al. The effectiveness of a biologic agent on axial manifestations of psoriatic arthritis. A twelve months observational study in a group of patients treated with etanercept. Clin Exp Rheumatol; 15:80–84, 2011. De Sá Pinto AL, Gualano B, Lima FR, Roschel H. Exercício físico nas doenças reumáticas: efeitos terapêuticos. São Paulo: Sarvier; 2011. <h3>Disclosure of Interest</h3> None declared