tbuckley/cabot-search huggingface dataset:
A European Phase II Study (BIOV-111) of Clofarabine (Evoltra®) in Refractory and Relapsed Childhood Acute Lymphoblastic Leukemia: Final Results.
Authors: Pamela Kearns, Gerard Michel, Brigitte Nelken, Simon Joel, Essam Al-Ghazaly, Auke Beishuizen, Valentino Conter, Gunter Henze, Andre Baruchel, Vaskar Saha
Journal: Blood (2007)
Sildenafil Prevents Podocyte Injury via PPAR-γ–Mediated TRPC6 Inhibition
Authors: Ramon Sonneveld, Joost G. Hoenderop, Andrea M. Isidori, Carole Henique, Henry B. Dijkman, Jo H. Berden, Pierre-Louis Tharaux, Johan van der Vlag, Tom Nijenhuis
Journal: Journal of the American Society of Nephrology (2016)

Transient receptor potential channel C6 (TRPC6) gain-of-function mutations and increased TRPC6 expression in podocytes induce glomerular injury and proteinuria. Sildenafil reduces TRPC6 expression and activity in nonrenal cell types, although the mechanism is unknown. Peroxisome proliferator-activated receptor γ (PPAR-γ) is a downstream target of sildenafil in the cyclic guanosine monophosphate (cGMP)-activated protein kinase G (PKG) axis. PPAR-γ agonists, like pioglitazone, appear antiproteinuric. We hypothesized that sildenafil inhibits TRPC6 expression in podocytes through PPAR-γ-dependent mechanisms, thereby counteracting podocyte injury and proteinuria. Treatment with sildenafil, the cGMP derivative 8-bromoguanosine 3',5'-cyclic monophosphate sodium salt (8-Br-cGMP), or pioglitazone dose-dependently downregulated podocyte injury-induced TRPC6 expression in vitro Knockdown or application of antagonists of PKG or PPAR-γ enhanced TRPC6 expression in podocytes and counteracted effects of sildenafil and 8-Br-cGMP. We observed similar effects on TRPC6 promoter activity and TRPC6-dependent calcium influx. Chromatin immunoprecipitation showed PPAR-γ binding to the TRPC6 promoter. Sildenafil or pioglitazone treatment prevented proteinuria and the increased TRPC6 expression in rats with adriamycin-induced nephropathy and mice with hyperglycemia-induced renal injury. Rats receiving PPAR-γ antagonists displayed proteinuria and increased podocyte TRPC6 expression, as did podocyte-specific PPAR-γ knockout mice, which were more sensitive to adriamycin and not protected by sildenafil. Thus, sildenafil ameliorates podocyte injury and prevents proteinuria through cGMP- and PKG-dependent binding of PPAR-γ to the TRPC6 promoter, which inhibits TRPC6 promoter activity, expression, and activity. Because sildenafil is approved for clinical use, our results suggest that additional clinical study of its antiproteinuric effect in glomerular disease is warranted.
ADNP Is a Therapeutically Inducible Repressor of WNT Signaling in Colorectal Cancer
Authors: Cristina Blaj, Agnes Bringmann, Eva Marina Schmidt, Manuela Urbischek, Sebastian Lamprecht, Thomas Fröhlich, Georg J. Arnold, Stefan Krebs, Helmut Blum, Heiko Hermeking, Andreas Jung, Thomas Kirchner, David Horst
Journal: Clinical Cancer Research (2016)

Purpose: Constitutively active WNT signaling is a hallmark of colorectal cancers and a driver of malignant tumor progression. Therapeutic targeting of WNT signaling is difficult due to high pathway complexity and its role in tissue homeostasis. Here, we identify the transcription factor ADNP as a pharmacologically inducible repressor of WNT signaling in colon cancer.Experimental Design: We used transcriptomic, proteomic, and in situ analyses to identify ADNP expression in colorectal cancer and cell biology approaches to determine its function. We induced ADNP expression in colon cancer xenografts by low-dose ketamine in vivo Clinical associations were determined in a cohort of 221 human colorectal cancer cases.Results: ADNP was overexpressed in colon cancer cells with high WNT activity, where it acted as a WNT repressor. Silencing ADNP expression increased migration, invasion, and proliferation of colon cancer cells and accelerated tumor growth in xenografts in vivo Treatment with subnarcotic doses of ketamine induced ADNP expression, significantly inhibited tumor growth, and prolonged survival of tumor-bearing animals. In human patients with colon cancer, high ADNP expression was linked to good prognosis.Conclusions: Our findings indicate that ADNP is a tumor suppressor and promising prognostic marker, and that ketamine treatment with ADNP induction is a potential therapeutic approach that may add benefit to current treatment protocols for patients with colorectal cancer. Clin Cancer Res; 23(11); 2769-80. ©2016 AACR.
The TEMPI Syndrome: Telangiectasias, Elevated Erythropoietin and Erythrocytosis, Monoclonal Gammopathy, Perinephric Fluid Collections, and Intrapulmonary Shunting
Authors: David B. Sykes, Wilfried A. Schroyens, Casey L. O'Connell, Donald I. Feinstein, Hasan Bazari, Douglas M. Dahl, Robert B. Colvin, Bernard P. Paelinck, Raul N. Uppot, Bart Op de Beeck, William Boswell, Noopur S. Raje, Nancy Lee Harris, Eyal C. Attar
Journal: Blood (2011)
Lack of Substantial Antithrombotic Effect of Low Circulating Coagulation Factor VII Levels in a Baboon Model of Acute Vascular Graft Thrombosis
Authors: Michael Wallisch, Greisel Jennifer, Erik I Tucker, Owen J.T. McCarty, Monica T Hinds, Sue Murray, Jeff Crosby, Brett P. Monia, Andras Gruber
Journal: Blood (2014)
The Utility of Consolidative Upfront High Dose Chemoradiotherapy and ASCT in Patients with Mantle Cell Lymphoma (MCL).
Authors: Daniel Persky, Carol S. Portlock, Simone Lessac-Chenen, Alexia Iasonos, Andrew D. Zelenetz, Tarun Kewalramani, David Rice, Joachim Yahalom, Stephen D. Nimer, Craig H. Moskowitz
Journal: Blood (2005)
Abstract 13653: Branched-Chain Amino Acids Ameliorate Heart Failure in Rats
Authors: Yohei Tanada, Tetsuo Shioi, Akira Kawamoto, Junji Okuda, Takeshi Kimura
Journal: Circulation (2013)

Introduction: Heart failure (HF) is associated with changes in energy metabolism of the heart, as well as in extra-cardiac organs such as skeletal muscles. Particularly, abnormal mitochondria are o...
Air Hunger
Authors: Erin M. Denney-Koelsch
Journal: Annals of Internal Medicine (2014)

On Being a Doctor7 October 2014Air HungerErin M. Denney-Koelsch, MDErin M. Denney-Koelsch, MDFrom University of Rochester Medical Center, Rochester, New York.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/M14-0327 Audio Reading - “Air Hunger” Audio. Michael A. LaCombe, MD, Annals Associate Editor, reads "Air Hunger," by E.M. Denney-Koelsch. Your browser does not support the audio element. Audio player progress bar Step backward in current audio track Play current audio trackPause current audio track Step forward in current audio track Mute current audio trackUnmute current audio track 00:00/ SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail It was Monday morning at 6:00 a.m., 2 hours from finishing a fulfilling but exhausting 2-week rotation as the attending on our busy inpatient palliative care service. I got into the shower to splash myself awake, grateful that my call was ending, eager to spend more time with my husband and two young children. I heard the pager vibrating on the counter and thought, “You've got to be kidding. Another ED admission?”While I was drying off, the pager went off again. “URGENT, CALL ASAP.” It was from the palliative care unit, and I knew whom this must be about: ... Author, Article, and Disclosure InformationAffiliations: From University of Rochester Medical Center, Rochester, New York.Corresponding Author: Erin M. Denney-Koelsch, MD, University of Rochester Medical Center, 601 Elmwood Avenue, Box 687, Rochester, NY 14642; e-mail, [email protected]rochester.edu. PreviousarticleNextarticle Advertisement Audio Reading - “Air Hunger” Audio. Michael A. LaCombe, MD, Annals Associate Editor, reads "Air Hunger," by E.M. Denney-Koelsch. Your browser does not support the audio element. Audio player progress bar Step backward in current audio track Play current audio trackPause current audio track Step forward in current audio track Mute current audio trackUnmute current audio track 00:00/ FiguresReferencesRelatedDetails Metrics 7 October 2014Volume 161, Issue 7Page: 530KeywordsBreadChildrenEmotionsHematology and oncologyInpatientsNursesOpioidsPalliative care ePublished: 7 October 2014 Issue Published: 7 October 2014 Copyright & PermissionsCopyright © 2014 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Disruption of TP53 function by Point Mutations and Deletions Is Associated with An Increased Risk of Disease Progression within Previously Treated, Relapsed Chronic Lymphocytic Leukemia Patients
Authors: Annika Dufour, Stefan K Bohlander, Evelyn Zellmeier, Gudrun Mellert, Karsten Spiekermann, Stephanie Schneider, Purvi Kakadia, Wolfgang Hiddemann, Jan Braess, Sim Truong, Nancy Patten, Lin Wu, Galina Salogub, Philippe Solal-Celigny, Anna Dmoszynska, Tadeusz Robak, Boris V Afanasiev, Marco Montillo, John Catalano, Christian H. Geisler, David Dornan, Ming Lin, Ru-Fang Yeh, Martin Weisser, Guillemette Duchateau-Nguyen, Giuseppe Palermo
Journal: Blood (2011)
CD19-Targeted Donor T Cells Exert Potent Graft Versus Lymphoma Activity and Attenuated Gvhd
Authors: Arnab Ghosh, Marco L. Davila, Lauren F. Young, Christopher Kloss, Gertrude Gunset, Odette M. Smith, Mallory L. West, Natalie V. Singer, Amanda M. Holland, Robert R. Jenq, Alan M. Hanash, Jarrod A. Dudakov, Enrico Velardi, Yusuke Shono, Michel Sadelain, Marcel R.M. van den Brink
Journal: Blood (2012)
Cord Blood Plasma Enhances Migration of Hematopoietic Stem and Progenitor Cells (HSPC)
Authors: James G Farmar, Alexander Wendling, Kevin Lynch, Jose Tomsig, Mariusz Z Ratajczak, Hongyan Lu, Amandeep Salhotra, Shicheng Yang, Xiao Huang, Harun El Masri, Mary J. Laughlin
Journal: Blood (2011)
SP0118 How to Optimize Doppler Settings for Fast Flow: Table 1.
Authors: W.A. Schmidt
Journal: Annals of the Rheumatic Diseases (2014)

<h3></h3> Several rheumatic diseases are affecting blood vessels. Vascular ultrasound is relevant in rheumatology particularly for large-vessel vasculitis, Raynaud9s phenomenon and venous thrombosis. Flow velocities are higher in large vessels when compared to intra-synovial vessels. Colour Doppler, not power Doppler ultrasound should be performed for evaluating large vessel. Power Doppler is used for low blood flow velocities in order to increase the sensitivity for detecting signals. Colour signal sensitivity is usually not a problem in large vessels. Furthermore, colour Doppler ultrasound allows detecting stenoses by demonstrating a phenomenon called "aliasing": Due to increased flow velocity in stenoses a mixture of colours appears. B-mode and colour Doppler frequency needs to be adjusted according how deeply the vessel is localized below the skin surface. Pulse repetition frequency (PRF) needs to be adjusted according to the blood flow velocities in the vessel (Table). It needs to be increased in case of fast flow for preventing aliasing and impaired image quality. It needs to be decreased in case of low flow velocities in order to provide enough sensitivity for detecting colour signals. In relatively small vessels like the temporal arteries the sonographer needs to make sure that the colour signal does not cover the wall when the colour gain is too high or that it only covers the centre of the lumen when the colour gain is too low. Gain settings need to be tested in normals before ultrasound is done for diagnosis of temporal arteritis. The optimal angle between sound waves and the vessel is 45°. If these are perpendicular the colour quality becomes inadaequate. Ultrasound machines provide a steer function for the colour box that needs to be used in this case. <h3>Conclusion</h3> Settings for large-vessel colour Doppler ultrasound include PRF, B mode frequency, colour frequency and colour gain. The colour gain needs to be adjusted so that the colour does not cover the vessel wall or, if too low, only covers the centre of the vessel lumen. The colour box needs to be steered in order to arrive at a good colour quality. <h3>Disclosure of Interest</h3> None declared <h3>DOI</h3> 10.1136/annrheumdis-2014-eular.6227
Changes of the Niche of Erythropoiesis Appear to Contribute to Severe Transfusion-Dependent Anemia in a Significant Proportion of Patients with Myelodysplastic Syndromes
Authors: Guntram Buesche, Aristoteles Giagounidis, Gudrun Göhring, Brigitte Schlegelberger, Arnold Ganser, Carlo Aul, Hans Heinrich Kreipe
Journal: Blood (2015)
TP53 Abnormalities in Chronic Lymphocytic Leukemia Exhibit a Disease Specific Profile: Meta-Analysis of 270 Mutations.
Authors: Thorsten Zenz, Jana Smadova, Dominik Vollmer, Martin Trbusek, Axel Benner, Sonja Häbe, Tina Denzel, Jitka Malcikova, Sim Truong, Nancy Patten, David Oscier, Rachel Ibbotson, Anne Gardiner, Ian Tracy, Ke Lin, Andrew Pettitt, Sarka Popsilova, Jiri Mayer, Hartmut Döhner, Stephan Stilgenbauer
Journal: Blood (2008)
Targeted Inhibition of Axl Primes Chronic Lymphocytic Leukemia B-Cells for Apoptosis: Synergistic/Additive Effects in Combination with Bruton Tyrosine Kinase Inhibitors
Authors: Sutapa Sinha, Justin Boysen, Michael Nelson, Charla Secreto, Steven L. Warner, David J. Bearss, Connie Lesnick, Tait D. Shanafelt, Neil E. Kay, Asish K Ghosh
Journal: Blood (2014)
Enhancing The Efficacy and Specificity Of Antibody-Based T Cell Retargeting Strategies Against Hematological Malignancies
Authors: Claudia Arndt, Marc Cartellieri, Roberta Aliperta, Stefanie Koristka, Irene Michalk, Martin Bornhäuser, Gerhard Ehninger, Michael Bachmann, Anja Feldmann
Journal: Blood (2013)
Weekend Drug Holiday of Dasatinib in CML Patients Not Tolerating Standard Dosing Regimens. Reducing Toxicity with Maintained Disease Control.
Authors: Paul La Rosee, Armin Leitner, Philippe Martiat, Thomas Klag, Samina Shazi, Anne Treschl, Martin C Müller, Thomas Schenk, Benjamin Hanfstein, Andreas Hochhaus
Journal: Blood (2009)
Transcriptional Regulator CNOT3 Defines an Aggressive Colorectal Cancer Subtype
Authors: Paloma Cejas, Alessia Cavazza, C.N. Yandava, Victor Moreno, David Horst, Juan Moreno-Rubio, Emilio Burgos, Marta Mendiola, Len Taing, Ajay Goel, Jaime Feliu, Ramesh A. Shivdasani
Journal: Cancer Research (2016)

Abstract Cancer cells exhibit dramatic alterations of chromatin organization at cis-regulatory elements, but the molecular basis, extent, and impact of these alterations are still being unraveled. Here, we identify extensive genome-wide modification of sites bearing the active histone mark H3K4me2 in primary human colorectal cancers, as compared with corresponding benign precursor adenomas. Modification of certain colorectal cancer sites highlighted the activity of the transcription factor CNOT3, which is known to control self-renewal of embryonic stem cells (ESC). In primary colorectal cancer cells, we observed a scattered pattern of CNOT3 expression, as might be expected for a tumor-initiating cell marker. Colorectal cancer cells exhibited nuclear and cytoplasmic expression of CNOT3, suggesting possible roles in both transcription and mRNA stability. We found that CNOT3 was bound primarily to genes whose expression was affected by CNOT3 loss, and also at sites modulated in certain types of colorectal cancers. These target genes were implicated in ESC and cancer self-renewal and fell into two distinct groups: those dependent on CNOT3 and MYC for optimal transcription and those repressed by CNOT3 binding and promoter hypermethylation. Silencing CNOT3 in colorectal cancer cells resulted in replication arrest. In clinical specimens, early-stage tumors that included &amp;gt;5% CNOT3+ cells exhibited a correlation to worse clinical outcomes compared with tumors with little to no CNOT3 expression. Together, our findings implicate CNOT3 in the coordination of colonic epithelial cell self-renewal, suggesting this factor as a new biomarker for molecular and prognostic classification of early-stage colorectal cancer. Cancer Res; 77(3); 766–79. ©2016 AACR.
Association between single nucleotide polymorphisms and side effects in nivolumab treated NSCLC patients
Authors: S. Bins, E.A. Basak, S. El Bouazzaoui, S.L.W. Koolen, C. van der Leest, S. Sleijfer, R. Debets, R.H.N. van Schaik, J.G.J.V. Aerts, R. Mathijssen
Journal: Annals of Oncology (2016)
The V50/V25 Ratio, a Marker of Small Airway Disease, Is Highly Predictive of Survival after Allogeneic Hematopoietic Cell Transplantation
Authors: Mika Nakamae, Hirohisa Nakamae, Mariko Yamashita, Mitsutaka Nishimoto, Yoshiki Hayashi, Hideo Koh, Takahiko Nakane, Yasuhiro Nakashima, Asao Hirose, Masayuki Hino
Journal: Blood (2014)
Idiopathic pulmonary fibrosis
Authors: O. J. Dempsey, D. Miller
Journal: BMJ (2013)

These discussions are selected from the weekly staff conferences in the Department of Medicine, University of California, San Francisco. Taken from transcriptions, they are prepared by Drs Homer A. Boushey, Professor of Medicine, and David G. Warnock, Associate Professor of Medicine, under the direction of Dr Lloyd H. Smith, Jr, Professor of Medicine and Associate Dean in the School of Medicine. Requests for reprints should be sent to the Department of Medicine, University of California, San Francisco, School of Medicine, San Francisco, CA 94143.
Collaboration between Activating Mutations in JAK2 and Trisomy 21 in the Acute Lymphoblastic Leukemias of Down Syndrome (DS).
Authors: Ithamar Ganmore, Dan Bercovich, Linda M. Scott, Anthony R. Green, Giovanni Cazzaniga, Andrea Biondi, Giuseppe Basso, Gunnar Cario, Martin Schrappe, Martin Stanulla, Sabine Strehl, Oskar A. Haas, Vera Binder, Arndt Borkhardt, Jan Trka, Bella Bielorei, Smadar Avigad, Batia Stark, Jean-Pierre Bourquin, Owen Smith, Helena Kempski, Shai Izraeli
Journal: Blood (2007)
Zoledronic Acid Inhibits Cell Growth of Multiple Myeloma Cells and Shows Synergistic Antimyeloma Effects with Bortezomib Via CD38 /cADPR /Ca2+ /Ras /Pakt /NF-Kb /Pim-2 Pathway
Authors: Rong Fu, Zhaoyun Liu, Hui Liu, Jia Song, Guojin Wang, Yihao Wang, Lijuan Li, Zonghong Shao
Journal: Blood (2015)
An Injectable, Click‐Cross‐Linked Small Intestinal Submucosa Drug Depot for the Treatment of Rheumatoid Arthritis
Authors: Kyungsook Kim, Ji Hoon Park, Seung Hun Park, Hye Yun Lee, Jae Ho Kim, Moon Suk Kim
Journal: Advanced Healthcare Materials (2016)

Here, a click‐cross‐linked small intestine submucosa (SIS) drug depot is described for the treatment of rheumatoid arthritis (RA). To the best of the knowledge, there have been no studies related to the intra‐articular injection of methotrexate (Met)‐loaded click‐cross‐linkable SIS (Met‐loaded Cx‐SIS) for RA treatment. As the key objective of this work, injectable formulations of tetrazine‐modified SIS (TE‐SIS) and transcyclooctene‐modified SIS (TC‐SIS) are employed as drug depots. Within a few seconds, the simple mixing of equal amounts of TE‐SIS and TC‐SIS suspensions forms a gelatinous click‐cross‐linked SIS (Cx‐SIS) drug depot in vitro and in vivo. The formed Cx‐SIS depot is maintained in the articular joint over an extended period, while SIS alone rapidly disappears. Injectable formulations of Met‐loaded Cx‐SIS and Met‐loaded SIS are prepared and then injected into articular joints to form drug depots. Compared to animals treated with Met‐loaded SIS, RA animals treated with Met‐loaded Cx‐SIS show effective RA repair, as well as extensive regeneration of chondrocytes and glycosaminoglycan deposits. Collectively, these results indicate that the Met‐loaded Cx‐SIS depot is successfully formed after intra‐articular injection of click‐cross‐linkable SIS, and that this formulation induces long‐lasting Met release and allows Met to act effectively in the articular joint, resulting in RA repair.
Humanized E17 Hemophilic Mice Are a Major Breakthrough in the Design of New Preclinical Models for Developing Factor VIII Products with Reduced Immunogenicity.
Authors: Birgit M. Reipert, Christina Hausl, Maria Sasgary, Maria Schuster, Rafi U. Ahmad, Bernhard Baumgartner, Josenato Ilas, Natalie Bauer, Hartmut Ehrlich, Hans Peter Schwarz
Journal: Blood (2007)
Marcks Marks Resistance to Proteasome Inhibitors: Exocytosis of Polyubiquitinated Proteins in Bortezomib-Resistant Leukemia Cells
Authors: Niels Franke, Gertjan J.L. Kaspers, Yehuda G Assaraf, Johan Van Meerloo, Denise Niewerth, Terzah M. Horton, Wee Joo Chng, Chonglei Bi, Rene X. Menezes, Renée J. Musters, Pino J. Poddighe, Floortje Kessler, Serge Smeets, Bauke Ylstra, Sonja Zweegman, Gerrit Jansen, Jacqueline Cloos
Journal: Blood (2015)
Transplant Outcomes after Topotecan-Melphalan-Cyclophosphamide (TMC) Conditioning for Autologous Stem Cell Transplantation for Multiple Myeloma. Comparison to Melphalan 200 mg/M2 (MEL200).
Authors: Michele Donato, Ana Aleman, Donna Weber, Michael Wang, Muzaffer Qazilbasch, Marilyn Davis, Linda Roden, Floralyn Mendoza, Richard Champlin, Sergio Giralt
Journal: Blood (2005)
Review of I. Glenn Cohen and Holly Fernandez Lynch, eds., <i>Human Subjects Research Regulation: Perspectives on the Future<sup>1</sup> 1. Cambridge, MA: The MIT Press, 2014, 373 pp., $35.00 Paperback</i>
Authors: Erin Phinney Johnson
Journal: The American Journal of Bioethics (2016)

"Review of I. Glenn Cohen and Holly Fernandez Lynch, eds., Human Subjects Research Regulation: Perspectives on the Future1 1. Cambridge, MA: The MIT Press, 2014, 373 pp., $35.00 Paperback." The American Journal of Bioethics, 16(12), pp. W15–W16
Peripheral Blood Stem Cells vs Bone Marrow for Matched Sibling Transplant in AML and ALL in First Remission.
Authors: Mark Kirschbaum, M. O’Donnell, R. Spielberger, R. Bhatia, V. Pullarkat, A. S. Stein, N. Kogut, E. Bolotin, K. Chang, J. Land, C. Sarkodee-Adoo, D. Snyder, S. J. Forman
Journal: Blood (2004)
The Clinical Spectrum of Acute GVHD: Beyond Day 100.
Authors: Daniel R. Couriel, Rima Saliba, Shubhra Gosh, Marcos De Lima, Sergio Giralt, Issa Khouri, Borje Andersson, Kerry Mickler, Zuraima Caldera, Yvonne Hsu, Joyce Neumann, Sharon Hymes, Stella Kim, Richard Champlin
Journal: Blood (2005)
The Significance of Megakaryocytic Transcription Factor Fli1 and Erythroid Transcription Factor EKLF in the Ribosomopathies: 5q Minus Syndrome and Diamond-Blackfan Anemia. the Role of Fli1 in p53 Regulation and in 5q Minus Syndrome Megakaryopoiesis,
Authors: Radana Neuwirtova, Ota Fuchs, Dagmar Pospisilova, Radek Cmejla, Monika Holicka, Martin Vostry, Arnost Kostecka, Hana Hajkova, Anna Jonasova, Jaroslav Cermak, Kyra Michalova, Jana Brezinova
Journal: Blood (2011)
Leukocyte Factor XII Mediates Inflammation and Its Deficiency Promotes Wound Healing
Authors: Evi Stavrou, Matthew J. Fullana, Gretchen LaRusch, Cindy Yushin Chang, Chao Fang, Howard J. Meyerson, Cheng-Kui Qu, Wen-Mei Yu, Gary E. Wnek, Alvin H. Schmaier
Journal: Blood (2012)
Cytotoxic Effect of Proteasome Inhibitor Bortezomib in Combination with Purine Nucleoside Analogues on Chronic Lymphocytic Leukemia Cells in Vitro.
Authors: Piotr Smolewski, Markus Duechler, Anna Linke, Barbara Cebula, Josef D. Schwarzmeier, Tadeusz Robak
Journal: Blood (2004)
Copper and Iron Status in Myelodysplastic Syndromes.
Authors: Zoi Saouli, Zisis Kontoninas, Fotios Girtovitis, Georgia Kaiafa, George Ntaios, Charalambos Andreadis, Helen Tsoukali, Apostolos Haztitolios, Athanasios Papadopoulos
Journal: Blood (2007)
Favorable Impact of Short Term Methotrexate on Early Immune Reaction and Non-Relapse Mortality in Umbilical Cord Blood Transplantation for Adult Patients.
Authors: Masato Watanabe, Hiroto Narimatsu, Seitaro Terakura, Keitaro Matsuo, Taku Oba, Masanobu Kasai, Hiroatsu Iida, Motohiro Hamaguchi, Akio Kohno, Makoto Murata, Masashi Sawa, Koichi Miyamura, Yoshihisa Morishita
Journal: Blood (2006)
Deregulated Cellular Iron Metabolism Factors Mediate Iron Overload in Myeloma Cells and Osteoclasts, and Promote Myeloma Growth and Bone Disease,
Authors: Rakesh Bam, Wen Ling, Sharmin Khan, Sathisha Upparahalli Venkateshaiah, Xin Li, Frits van Rhee, Bijay Nair, Saad Usmani, Bart Barlogie, John D Shaughnessy, Joshua Epstein, Elias J. Anaissie, Shmuel Yaccoby
Journal: Blood (2011)