tbuckley/cabot-search huggingface dataset:
Survey of State Laws and Regulations for Radiation Control
Authors: N S BLACKMAN
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Radionuclide targeting of bone metastases: which efficacy?
Authors: S Leyvraz, P Burckhardt
Journal: Journal of Clinical Oncology (1990)

Article Tools Article Tools OPTIONS & TOOLS Export Citation Track Citation Add To Favorites Rights & Permissions COMPANION ARTICLES No companion articles ARTICLE CITATION DOI: 10.1200/JCO.1990.8.9.1598 Journal of Clinical Oncology - published online before print September 22, 2016 PMID: 2391559 Radionuclide targeting of bone metastases: which efficacy? S LeyvrazxS LeyvrazSearch for articles by this author , P BurckhardtxP BurckhardtSearch for articles by this author https://doi.org/10.1200/JCO.1990.8.9.1598 PDF "Radionuclide targeting of bone metastases: which efficacy?." Journal of Clinical Oncology, 8(9), pp. 1598–1599© 1990 by American Society of Clinical Oncology
E 1308: A phase II trial of induction chemotherapy (IC) followed by cetuximab with low dose versus standard dose IMRT in patients with human papilloma virus (HPV)-associated resectable squamous cell carcinoma of the oropharynx (OPSCC).
Authors: Shanthi Marur, Shuli Li, Anthony Cmelak, Maura L. Gillison, Robert L. Ferris, Julie E. Bauman, Weiqiang Zhao, William H. Westra, Christine H. Chung, Lynne I. Wagner, David R. Trevarthen, Balkrishna N. Jahagirdar, A. Dimitrios Colevas, Barbara Burtness
Journal: Journal of Clinical Oncology (2013)

6005 Background: HPV is associated with 60-80% of OPSCC. E2399 results showed IC followed by (f/b) paclitaxel (P)/3D RT (70Gy) improved 2-yr progression-free (PFS) for HPV+ compared to HPV- OPSCC. We studied a regimen with 20% radiation dose reduction to 54Gy in HPV + OPSCC patients (pts) with a clinical complete response (CCR) to IC. Methods: Stage III/IVA,B resectable HPV+ OPSCC were included. Eligible pts received IC q3 week x 3 with P 90mg/m2 days (D) 1,8, 15, cisplatin (CDDP) 75mg/m2 D1, and cetuximab (C) 400 mg/m2 D1, cycle 1 f/b C 250 mg/m2 weekly. Primary tumor and involved nodal response to IC were determined independently. Pts recieved IMRT 54Gy/27 fxs with weekly C for CCR vs. 69.3Gy/33 fxs with weekly C if &lt;CCR. Primary endpoint was 2-year PFS; secondary endpoints were toxicity, OS, response rate, QOL and correlative biomarkers. Results: From March 2010 to Oct 2011, 90 pts were enrolled (80 analyzable). Median age was 57 years, 95% men, 93% Caucasian, 91% PS 0, 46% never smokers, 84% not current smokers. Nodal stage: 39%-N2B, 29%-N2C, T stage: 23%-T1, 50%-T2, 16%-T3, 10%-T4. 96% received all 3 cycles of IC. Grade 3/4 toxicities included: rash (25%), neutropenia (11%). During CRT: oral mucositis (31%), dysphagia (17%), radiation dermatitis (8%). Response: Biopsy at primary site post- baseline measurements rendered 7/80 pts unevaluable (UE), 6/7 had investigator-reported CCR to IC. The centrally reviewed and investigator reported primary site CCR rate to IC was 63.8% ( 95% CI: 52.2%, 74.2%) and 71.3% (95% CI: 60.0%, 80.8%), respectively. Radiation: 73.8% (59/80 pts) received low dose IMRT/C to primary [54Gy (56), 52Gy (1), 40Gy (2)]. Best overall clinical response was 86% (CR +PR+SD) with 14% UE. Rate of post-treatment neck dissection in low dose vs other RT gp is 13.4% vs 22.2% ( p value of 0.46), respectively. Median follow up is 11.8 months. Conclusions: Overall, IC with P, CDDP and C f/b low dose RT with C was well tolerated, with all pts responding and very low grade 3/4 toxicities. Data on PFS are premature. A 2 year PFS of 85% or better will be considered worthy of further study. Clinical trial information: NCT01084083.
Response to presidential address: unity amidst diversity: future challenges
Authors: C C Nadelson
Journal: American Journal of Psychiatry (1985)

M y presence here today as the Association’s first woman president makes an important statement for American psychiatry. I hope that the issue of gender and leadership has now been put aside and that in this 141st year of APA history we have changed direction. I am honored by your trust in me and proud to represent you. It is a special personal pleasure and privilege to follow John Talbott and to respond to his eloquent address. John and Sue Talbott have been my close friends for almost 25 years. We met in 1961 when J ohn and I were interns together. We supported each other through that intense year; we learned how to work together, how to share, how to agree, and how to disagree without losing sight of a deep respect and caring that began then and grew over time. This past year has taken us back to the excitement of that beginning. This year has also been an opportunity for me to get to know and work with our extraordinary APA staff and with so many members. My friends, my family, my patients, and my department have had to put up with absences, distractions, last-minute changes, and the inevitable black moods occasioned by the demands of the work and the pressures of our times. They are prepared for an even more intense year to come. I am grateful to all of you for your help and your faith in me and for this beginning for APA women. For the year of my presidency, I have chosen the theme “Unity Amidst Diversity: Future Challenges.” The title is meant to emphasize the need for collaboration and cooperation among psychiatrists and with colleagues in related fields. While we recognize that fundamental and substantive differences exist on many issues and priorities, we know that such differences are inevitable when dedicated people search for solutions to complex problems. Diversity and difference can expand rather than limit our perspective. We must be
P0857 : 98% SVR12 in Korean and Taiwanese patients with chronic genotype 1 HCV infection receiving 12 weeks of ledipasvir/sofosbuvir: Results from an international, multicenter phase 3 study
Authors: Y.-S. Lim, W.-L. Chuang, S.-H. Ahn, C.-Y. Peng, S.-W. Paik, R.-N. Chien, C.-J. Chu, J.C. Yang, H. Mo, B. Gao, P.S. Pang, S.J. Knox, J.G. McHutchison, Y.-J. Lee, T.-T. Chang, S.-H. Jeong, K.-H. Han, J.-H. Kao
Journal: Journal of Hepatology (2015)
Effect on Mice of Oral Painting of Cigarette-Smoke Condensate
Authors: Joseph A. Dipaolo, George E. Moore
Journal: JNCI Journal of the National Cancer Institute (1959)

The oral area of mice of both sexes was painted with tobacco tar for 13 months. “Tar”-painted animals had more lung adenomas than animals in the acetone control groups. No bladder tumors developed in Swiss ICR/Ha strain mice in the experimental conditions of this experiment.
Characterisation of swabbing for virological analysis in the Spanish Influenza Sentinel Surveillance System during four influenza seasons in the period 2002-2006
Authors: A Larrauri, S De Mateo
Journal: Eurosurveillance (2007)

This study sought to characterise the swabbing pattern in the Spanish Influenza Sentinel Surveillance System (SISSS) and ascertain to what extent the system meets the guidelines currently being drafted by The European Influenza Surveillance Scheme (EISS). Data on seasons 2002/2003 to 2005/2006 were drawn from SISSS. The study analysed collection and dispatch of swab specimens for virological analysis by reference to variables relating to patient sex, age group, vaccination status, specimen collection period, period of influenza activity, time of swabbing and epidemiological season. SISSS adapts to EISS recommendations with respect to the specimen collection period and period of influenza activity, but there is a tendency to collect fewer specimens than recommended as the age of patients increases, and in the case of elderly patients (65 years and older), frequency of collection is clearly insufficient. Furthermore, sentinel physicians collect a higher percentage of specimens in cases where patients have received the influenza vaccine.
Mental Illness Stigma as a Barrier to Psychosocial Services for Cancer Patients
Authors: Alicia K. Matthews, Patrick W. Corrigan, Judith Lee Rutherford
Journal: Journal of the National Comprehensive Cancer Network (2003)

Empirically validated psychosocial interventions have been shown to improve adjustment and coping among cancer patients. Therefore, an emerging standard of practice is to integrate supportive services for cancer patients into the medical management of the disease. However, unanticipated barriers may negatively influence receptivity to psychosocial services. For example, among the general population, two-thirds of individuals in need of psychiatric services do not receive them. Numerous barriers have been reported that interfere with receipt of mental health services among members of the general population. In addition to access issues, stigma associated with mental illness and its treatment represents a significant barrier to care. Stigma associated with mental illness and mental health services use is an under-researched barrier to the effective management of the psychosocial sequelae of a cancer diagnosis and treatment. This article reviews the relevant literature on mental health stigma and makes recommendations for increasing access to psychosocial services for cancer patients and their families.
Abstract PR06: The enhancer landscape involves a core noncoding RNA protein interaction network for <i>C-MYC</i> expression
Authors: Fan Zhang, Won-min Song, SiDe Li, Vashisht Ajay, Francesca Aguilo, Anindya Bagchi, James A. Wohlschlegel, Bin Zhang, Martin Walsh
Journal: Cancer Research (2016)

Abstract Many long non-coding RNAs (lncRNAs) that regulate the capacity of cells to undergo oncogenic transformation still remain unknown. However, their involvement in chromatin organization has been an emerging principle in cancer epigenomics. This recent concept has been documented through recent studies of the gene -poor chromosomal region 8q24 surrounding the C-MYC locus to understand the mechanisms enforcing or suppressing tumor cell growth from C-MYC transcription levels. In light of such examples informing us of the DNA elements and the epigenomic composition that become integrated into molecular programs that regulate C-MYC, some lncRNAs in non-genic regions are considered landmarks that enforce chromatin state changes to accommodate C-MYC expression. Here, we use an integrative genomic and proteomic approach to gain insight of how an endogenously tagged lncRNA PCAT-1 utilizes the chromatin and biochemical context to shape C-MYC locus topology to promote tumor cell growth, survival and fitness. Our results now find that WDR74 forms an integrative hub involving recognition of the m7G cap of lncRNA transcripts along with, RNMT, RAM, BRD4, β catenin, EZH2 that assist in a program that enforce C-MYC transcription and stabilize transcripts through utilizing a comprehensive mixture of cis-acting DNA elements, lncRNAs and trans functioning transcriptional and RNA capping complexes for prostate tumor cell growth. Our results now place the lncRNA PCAT-1 and the novel interacting WD40 repeat protein WDR74 at the axis along with β catenin, BRD4 and EZH2, and additional RBPs as a non -canonical chromatin complex to shape the chromosomal topology that benefit prostate cancer cell growth. Citation Format: Fan Zhang, Won-min Song, SiDe Li, Vashisht Ajay, Francesca Aguilo, Anindya Bagchi, James A. Wohlschlegel, Bin Zhang, Martin Walsh. The enhancer landscape involves a core noncoding RNA protein interaction network for C-MYC expression. [abstract]. In: Proceedings of the AACR Special Conference on Noncoding RNAs and Cancer: Mechanisms to Medicines ; 2015 Dec 4-7; Boston, MA. Philadelphia (PA): AACR; Cancer Res 2016;76(6 Suppl):Abstract nr PR06.
Blood oxygenation and decarboxylation determinants during venovenous ECMO for respiratory failure in adults
Authors: Matthieu Schmidt, Guillaume Tachon, Christine Devilliers, Grégoire Muller, Guillaume Hekimian, Nicolas Bréchot, Sybille Merceron, Charles Edouard Luyt, Jean-Louis Trouillet, Jean Chastre, Pascal Leprince, Alain Combes
Journal: Intensive Care Medicine (2013)
Persecutory delusions: a cybernetic model
Authors: F T Melges, A M Freeman
Journal: American Journal of Psychiatry (1975)

The authors propose a cybernetic model for the formation and maintenance of persecutory delusions. During the formation of persecutory ideation, the threat of loss of control over the self or others interacts with predictions of control from others. This interaction may result in feelings of alien control followed by persecutory explanations. Since the persecutory explanations provide the individual with a new goal of resisting others' influence in order to prevent being controlled, they reduce the threat of loss of self-control. This is how persecutory delusions are maintained.
Incidence of AIDS cases in Spanish penal facilities through the capture-recapture method, 2000
Authors: E Acin, P. Gomez, P. Hernando, I Corella
Journal: Eurosurveillance (2003)

Three available sources of information used in the surveillance of AIDS in Spanish prisons were used to carry out a capture-recapture study. Results showed the register of AIDS cases (RCS) considerably underestimates the incidence of this disease in prisons as it covers only 50% of cases. This study highlights the need to use additional sources to the RCS to evaluate the real incidence of AIDS in prisons in Spain.
Potency Tests of Semple-Type Rabies Vaccines of Nervous Tissue Origin for Use in Animals
Authors: D J DEAN, W M EVANS, I SHERMAN
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Inherited breast cancer: increasingly familiar territory.
Authors: J Garber
Journal: Journal of Clinical Oncology (1998)

Article Tools Article Tools OPTIONS & TOOLS Export Citation Track Citation Add To Favorites Rights & Permissions COMPANION ARTICLES No companion articles ARTICLE CITATION DOI: 10.1200/JCO.1998.16.5.1639 Journal of Clinical Oncology - published online before print September 21, 2016 PMID: 9586872 Inherited breast cancer: increasingly familiar territory. J GarberxJ GarberSearch for articles by this author https://doi.org/10.1200/JCO.1998.16.5.1639 First Page PDF © 1998 by American Society of Clinical Oncology
Goals and methods of audit should be reappraised
Authors: J. Bain
Journal: BMJ (1996)

1958 63 68 73 78 83 88 93 Year Fig 1-Proportion of editorials devoted to medicine, administration, and other topics in first four months issues of BMJ at five year intervals, 1958-93 latter figure being the highest in the previous 35 years.The proportion of editorials about medical matters fell from a peak of 77% (86/113) to 49% (47/96) over the same period (fig 1).This audit shows a shift in the subject matter covered by editorials in the BMJ since 1978, from medical to administrative topics.The audit covered only the editorials, and we are aware that the BMJ' has taken initiatives to increase its coverage of medical topics-for example, it has introduced the ABC and Recent Advances series.Scheckler, however, advised that when one reads a journal one should always read the editorials first.3It is important that the BMJ brings the effects of any changes in NHS administration to readers' attention, but it must surely be a matter for con- cern when this results in fewer editorials on medical topics.We have not yet assessed whether this trend is occurring in other medical journals.
Reanalyses of NSABP Studies
Authors: E. J. Sondik
Journal: JNCI Journal of the National Cancer Institute (1994)

Journal Article Reanalyses of NSABP Studies Get access Edward J. Sondik Edward J. Sondik *Acting Deputy Director, National Cancer InstituteBethesda, Md Correspondence to : Edward J. Sondik, Ph.D., National Institutes of Health, Bldg. 31, Rm. 11A49, Bethesda, MD 20892. Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 86, Issue 9, 4 May 1994, Page 655, https://doi.org/10.1093/jnci/86.9.655 Published: 04 May 1994
Atypical Presentations of Hand, Foot, and Mouth Disease Caused by Coxsackievirus A6 — Minnesota, 2014
Authors: Vicki W. Buttery, Cynthia Kenyon, Stacey Grunewald, M. Steven Oberste, W. Allan Nix
Journal: MMWR Morbidity and Mortality Weekly Report (2015)

In June, 2014, the Minnesota Department of Health (MDH) was notified of a suspected varicella case in a child aged 2 years. The patient had a generalized rash with relative sparing of the trunk and was hospitalized overnight for treatment of dehydration. The child's mother, who was near the end of a pregnancy, also had a generalized rash, which included the perineal area. Identifying the cause of the rash was important to determine whether administration of varicella zoster immune globulin was indicated to prevent neonatal varicella. Enterovirus was detected in specimens from the woman and child by reverse transcriptase-polymerase chain reaction (RT-PCR) testing performed at MDH; partial genome sequencing by CDC showed that both patients were infected with coxsackievirus A6 (CVA6), one of the members of the genus Enterovirus that causes hand, foot, and mouth disease (HFMD).
CIS is a potent checkpoint in NK cell–mediated tumor immunity
Authors: Rebecca B Delconte, Tatiana B Kolesnik, Laura F Dagley, Jai Rautela, Wei Shi, Eva M Putz, Kimberley Stannard, Jian-Guo Zhang, Charis Teh, Matt Firth, Takashi Ushiki, Christopher E Andoniou, Mariapia A Degli-Esposti, Phillip P Sharp, Caroline E Sanvitale, Giuseppe Infusini, Nicholas P D Liau, Edmond M Linossi, Christopher J Burns, Sebastian Carotta, Daniel H D Gray, Cyril Seillet, Dana S Hutchinson, Gabrielle T Belz, Andrew I Webb, Warren S Alexander, Shawn S Li, Alex N Bullock, Jeffery J Babon, Mark J Smyth, Sandra E Nicholson, Nicholas D Huntington
Journal: Nature Immunology (2016)
Normal Antibody-Dependent Killer Cell Function in Patients With Chronic Lymphocytic Leukemia 2
Authors: J. Bruce Smith, Regina P. Knowlton, Lawrence S. Koons
Journal: JNCI Journal of the National Cancer Institute (1977)

Unfractionated mononuclear peripheral blood leukocytes (PBL) and nylon wool-nonadherent (8-cell-depleted and T- and null-cell-enriched) cells from normal control individuals and untreated patients with chronic lymphocytic leukemia (CLL) were tested for killer cell function in an antibody-dependent cell-mediated cytotoxicity assay. Killer cell activity was present in unfractionated cells from normal individuals and was enriched after removal of adherent cells. Target cell killing by unfractionated mononuclear cells from CLL patients was deficient in 5 of 6 patients tested, but after removal of adherent cells it was approximately equal to that of normal nonadherent cells. Our results indicate that the apparent deficit of killer cells in unfractionated PBL from some CLL patients is due to dilution of killer cells and not to an intrinsic defect in the function of these cells, the presence of suppressor cells in the adherent population, or suppression of killer cell function by serum factors.
Depression through the first year after the death of a spouse
Authors: S Zisook, S R Shuchter
Journal: American Journal of Psychiatry (1991)

This study assesses the frequency of depressive syndromes during the first 13 months after the death of a spouse.Men and women whose spouses had recently died were identified through death certificate records. These subjects completed a multidimensional questionnaire and were interviewed 7-8 weeks (2 months) after the death. Follow-up questionnaires were completed 7 and 13 months after the death. The questionnaires contained specific items corresponding to DSM-III-R criteria for depressive episodes as well as other widely used measures of depressive symptoms such as the Zung Depression Scale and the Hopkins Symptom Checklist.Eighty-four (24%) of 350 widows and widowers met criteria for depressive episodes at 2 months, 72 (23%) of 308 did so at 7 months, and 46 (16%) of 286 did so at 13 months. At each time period, the prevalence was substantially higher than the 4% rate of depressive episodes observed in a comparison group of 126 subjects whose spouses were still living. Widows and widowers most likely to meet criteria for depressive episodes 13 months after the bereavement were younger, had past histories of major depression, were still grieving 2 months after the loss, and met DSM-III-R criteria for depressive episodes 2 and/or 7 months after the death.Depressive episodes are common after the death of a spouse. Clinicians should maintain a high index of suspicion for the possibility of depression, particularly in young widows and widowers who have a past history of depression or who experience a full depressive syndrome soon after the loss.