Combination Therapy for Rheumatoid Arthritis
Authors: Jean Sibilia
Journal: Annals of Internal Medicine (2002)

Summaries for Patients5 November 2002Combination Therapy for Rheumatoid ArthritisSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-137-9-200211050-00003 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail What is the problem and what is known about it so far?Rheumatoid arthritis (RA) is a chronic disease that causes painful, swollen, and deformed joints. It is caused by inflammation of the tissue linings (membranes) of joints. It usually affects the small joints of the hands and feet but may develop in any joint. People with RA usually have flares of joint pain and stiffness that last weeks to months. Between flares, people with RA are relatively symptom free.There is no cure for RA. Repeated attacks are painful and destroy joints. About 1 in 10 persons with RA ... Author, Article, and Disclosure InformationAffiliations: The summary below is from the full report titled “Concomitant Leflunomide Therapy in Patients with Active Rheumatoid Arthritis despite Stable Doses of Methotrexate. A Randomized, Double-Blind, Placebo-Controlled Trial.” It is in the 5 November 2002 issue of Annals of Internal Medicine (volume 137, pages 726-733). The authors are JM Kremer, MC Genovese, GW Cannon, JR Caldwell, JJ Cush, DE Furst, ME Luggen, E Keystone, MH Weisman, WM Bensen, JL Kaine, EM Ruderman, P Coleman, DL Curtis, EJ Kopp, SM Kantor, J Waltuck, HB Lindsley, JA Markenson, V Strand, B Crawford, I Fernando, K Simpson, and JM Bathon.Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. The summaries may be reproduced for not-for-profit educational purposes only. Any other uses must be approved by the American College of Physicians-American Society of Internal Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoConcomitant Leflunomide Therapy in Patients with Active Rheumatoid Arthritis despite Stable Doses of Methotrexate Joel M. Kremer , Mark C. Genovese , Grant W. Cannon , Jacques R. Caldwell , John J. Cush , Daniel E. Furst , Michael E. Luggen , Ed Keystone , Michael H. Weisman , William M. Bensen , Jeffrey L. Kaine , Eric M. Ruderman , Patricia Coleman , David L. Curtis , Elliot J. Kopp , Seth M. Kantor , Jonathan Waltuck , Herbert B. Lindsley , Joseph A. Markenson , Vibeke Strand , Bruce Crawford , Indra Fernando , Karen Simpson , and Joan M. Bathon Metrics 5 November 2002Volume 137, Issue 9Page: I-42KeywordsArthralgiaDiarrheaDisease modifying antirheumatic drugsInflammationLiverMethotrexateRheumatoid arthritisSigns and symptomsStiffnessToxicity ePublished: 5 November 2002 Issue Published: 5 November 2002 Copyright & PermissionsCopyright © 2002 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...