Cardiovascular Mortality Associated With 5 Leading Risk Factors
Authors: William B. Grant, Luca Mascitelli, Mark R. Goldstein
Journal: Annals of Internal Medicine (2016)

Letters5 April 2016Cardiovascular Mortality Associated With 5 Leading Risk FactorsWilliam B. Grant, PhD, Luca Mascitelli, MD, and Mark R. Goldstein, MDWilliam B. Grant, PhDFrom Sunlight, Nutrition, and Health Research Center, San Francisco, California; Comando Brigata Alpina “Julia”/Multinational Land Force, Medical Service, Udine, Italy; and NCH Physician Group, Naples, Florida.Search for more papers by this author, Luca Mascitelli, MDFrom Sunlight, Nutrition, and Health Research Center, San Francisco, California; Comando Brigata Alpina “Julia”/Multinational Land Force, Medical Service, Udine, Italy; and NCH Physician Group, Naples, Florida.Search for more papers by this author, and Mark R. Goldstein, MDFrom Sunlight, Nutrition, and Health Research Center, San Francisco, California; Comando Brigata Alpina “Julia”/Multinational Land Force, Medical Service, Udine, Italy; and NCH Physician Group, Naples, Florida.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/L15-0569 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:The paper by Patel and colleagues used data from 50 states plus the District of Columbia to develop a model to explain risk factors for cardiovascular disease (CVD) mortality in 2009–2010 (1). Their model included elevated cholesterol level, diabetes, hypertension, obesity, and current smoking. Because the data from NHANES (National Health and Nutrition Examination Survey) used in their model were provided, we decided to reexamine their model. We analyzed the data using SPSS 20.0 (IBM). In single linear regression analysis, only 3 of the factors were significantly correlated with CVD mortality rates: Hypertension was most important, followed ...References1. Patel SA, Winkel M, Ali MK, Narayan KM, Mehta NK. Cardiovascular mortality associated with 5 leading risk factors: national and state preventable fractions estimated from survey data. Ann Intern Med. 2015;163:245-53. [PMID: 26121190]. doi:10.7326/M14-1753 LinkGoogle Scholar2. Montezano AC, Dulak-Lis M, Tsiropoulou S, et al. Oxidative stress and human hypertension: vascular mechanisms, biomarkers, and novel therapies. Can J Cardiol. 2015;31:631-41. [PMID: 25936489] doi:10.1016/j.cjca.2015.02.008 CrossrefMedlineGoogle Scholar3. Chiang CE, Wang TD, Ueng KC, Lin TH, et al. 2015 guidelines of the Taiwan Society of Cardiology and the Taiwan Hypertension Society for the management of hypertension. J Chin Med Assoc. 2015;78:1-47. [PMID: 25547819] doi:10.1016/j.jcma.2014.11.005 CrossrefMedlineGoogle Scholar4. Gebreab SY, Davis SK, Symanzik J, et al. Geographic variations in cardiovascular health in the United States: contributions of state- and individual-level factors. J Am Heart Assoc. 2015;4:e001673. [PMID: 26019131] doi:10.1161/JAHA.114.001673 CrossrefMedlineGoogle Scholar5. Patterson CC, Blankenberg S, Ben-Shlomo Y, et al. Which biomarkers are predictive specifically for cardiovascular or for non-cardiovascular mortality in men? Evidence from the Caerphilly Prospective Study (CaPS). Int J Cardiol. 2015;201:113-8. [PMID: 26298350] doi:10.1016/j.ijcard.2015.07.106 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Sunlight, Nutrition, and Health Research Center, San Francisco, California; Comando Brigata Alpina “Julia”/Multinational Land Force, Medical Service, Udine, Italy; and NCH Physician Group, Naples, Florida.Disclosures: Authors have disclosed no conflicts of interest. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L15-0569. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoCardiovascular Mortality Associated With 5 Leading Risk Factors: National and State Preventable Fractions Estimated From Survey Data Shivani A. Patel , Munir Winkel , Mohammed K. Ali , K.M. Venkat Narayan , and Neil K. Mehta Cardiovascular Mortality Associated With 5 Leading Risk Factors Shivani A. Patel , Neil K. Mehta , and Mohammed K. Ali Metrics 5 April 2016Volume 164, Issue 7Page: 510KeywordsCardiovascular diseasesCholesterolDeath ratesHealth surveysHypertensionLinear regression analysisMedical risk factorsMortalityObesitySodium ePublished: 5 April 2016 Issue Published: 5 April 2016 Copyright & PermissionsCopyright © 2016 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...