tbuckley/cabot-search huggingface dataset:
S43 Hypoxia upregulates PI3KINASE-dependent neutrophil degranulation and neutrophil-mediated tissue injury
Authors: KM Lodge, K Hoenderdos, AJ Robbins, DM Storisteanu, ER Chilvers, W Li, AM Condliffe
Journal: Thorax (2016)

<h3>Introduction</h3> Damage to host tissue from persistent neutrophilic inflammation is implicated in the pathogenesis of many diseases, including chronic obstructive pulmonary disease (COPD). Infected/inflamed tissues can be profoundly hypoxic; this state may synergise with inflammatory cytokines to promote a destructive neutrophil phenotype with enhanced potential for tissue damage. <h3>Methods</h3> Neutrophils isolated from COPD patients or healthy volunteers were incubated under normoxia (21% O2) or hypoxia (0.8% O2) before treatment with priming (GM-CSF/PAF/TNF-α) and stimulating (fMLP) agents, with/without PI3Kinase inhibitors (pan/γ/δ). Neutrophil elastase (NE) activity was measured by Enzchek® assay. Western blotting for total and phosphorylated Akt was performed using cell lysates. Neutrophil extracellular trap (NET) production was assessed by fluorescence absorbance. Neutrophil supernatants were incubated with primary human pulmonary artery endothelial cells (HPAEC); death and detachment were measured by MTT assay and confocal microscopy. Precipitated neutrophil supernatants were separated by SDS polyacrylamide gel electrophoresis (PAGE) and silver stained. S100A8/A9 homo- and heterodimer content of neutrophil supernatants was assessed by ELISA. <h3>Results</h3> Hypoxia increased NE release in an agonist- and PI3K-γ-dependent manner, with more pronounced hypoxic degranulation responses seen in exacerbating COPD patients. Hypoxia augmented resting and cytokine-stimulated Akt phosphorylation; PI3K-γ inhibition abrogated Akt phosphorylation and prevented the hypoxic uplift of NE release. Hypoxia did not increase NET production in resting or GM-CSF/fMLP treated cells. Hypoxic neutrophil supernatants induced extensive HPAEC detachment and death, which was prevented by co-incubation with alpha-1 antitrypsin. Silver stained protein bands from precipitated neutrophil supernatants separated by SDS-PAGE were identified by mass spectrometry, suggesting a hypoxic increase in damage associated molecular pattern (DAMP) proteins S100A8 and S100A9. When interrogated by ELISA, there was no difference between the amount of S100A8/A9 hetero- or homodimers in normoxic versus hypoxic supernatants. <h3>Conclusion</h3> Hypoxia augments neutrophil degranulation in an agonist- and PI3K-γ-dependent manner, which may be further increased during COPD exacerbations. Hypoxic neutrophil supernatants have enhanced capacity to damage endothelial cells <i>in vitro</i>, likely due to increased release of NE. The contribution of S100A8/A9 proteins to this damage is currently unclear. Hence, hypoxia promotes a destructive histotoxic neutrophil phenotype with potential relevance to diseases such as COPD.
The impact of body fat distribution on neo-adjuvant chemotherapy for advanced breast cancer.
Authors: Toshiaki Iwase, Takafumi Sangai, Hiroshi Fujimoto, Masahiro Sakakibara, Takeshi Nagashima, Masaru Miyazaki
Journal: Journal of Clinical Oncology (2015)

e11517 Background: Obesity-linked cancer has become a worldwide problem. Obesity increases dysfunctional fat cells and promotes cancer growth. Recent research demonstrated that endocrine function of fat cells was different depending on their distribution. However, only a few studies have been performed concerning the relationship between body fat distribution and treatment outcome. Therefore, we set out to clarify the effect of body fat distribution on neo-adjuvant chemotherapy (NAC) for advanced breast cancer. Methods: A total of 172 NAC cases between January 2004 and December 2012 were included. Abdominal circumference (AC), subcutaneous fat area (SFA), visceral fat area (VFA), and skeletal muscle area (SMA), were calculated as body composition (BC) parameters. Liver/Spleen Hounsfield Unit ratio (L/S ratio) was calculated as a surrogate parameter for fat accumulation in internal organs. Those parameters were calculated using computed tomography volume analyzer. The relationships between patient characteristics, body mass index (BMI), BC parameters, L/S ratio, pathological complete response (pCR) and survival were analyzed. Results: In BC parameters, AC, SFA, VFA, and L/S ratio were significantly correlated to BMI (p < 0.05). When divided by menopausal status, those parameters were significantly increased after menopause, while SMA was decreased (p < 0.05). In addition, VFA/SFA ratio was significantly increased after menopause despite no significant change in BMI. A total of 46 cases achieved pCR. However, BC parameters were not associated with pCR. Survival analysis demonstrated high VFA group ( > 100cm2) was significantly had worse distant disease-free survival (DDFS) compared to the low VFA group (p < 0.05). Moreover, that difference was more significant in postmenopausal group. Although fatty liver group showed shorter median DDFS, it was nothing significant. Multivariate analysis showed VFA, pCR, and subtypes were independent prognostic factors for DDFS. Conclusions: The present study demonstrated that increased visceral fat after menopause was significantly related to the worse outcome. It is probable that appropriate interventions targetting the increased visceral fat will improve the NAC outcome.
Prognostic Value of Angiogenic Factors (Vacular Endothelial Growth Factor [VEGF] and Basic Fibroblast Growth Factor [bFGF]) and Endostatin in Patients with Non-Hodgkin Lymphoma.
Authors: Jean Abou Yared, Theodore Girinsky, Serge Koscielny, Vincent Ribrag, Patrice Carde, Suzanna Ceapa, Christophe Ferme
Journal: Blood (2008)
A phase 2 study of BGJ398 in patients (pts) with advanced or metastatic FGFR-altered cholangiocarcinoma (CCA) who failed or are intolerant to platinum-based chemotherapy.
Authors: Milind M. Javle, Rachna T. Shroff, Andrew Zhu, Saeed Sadeghi, SuPin Choo, Mitesh J. Borad, Maeve Aine Lowery, Anthony El-Khoueiry, Teresa Macarulla, Philip Agop Philip, Do-Youn Oh, Eric Van Cutsem, Kun-Huei Yeh, Randi Isaacs, Carolyn McGarry, Suman Sen, Tanios S. Bekaii-Saab
Journal: Journal of Clinical Oncology (2016)

335 Background: CCA is a hepatobiliary malignancy with poor prognosis and few treatment options following cytotoxic therapy in the first-line metastatic setting. The fibroblast growth factor receptor (FGFR) axis may promote CCA tumorigenesis. FGFR2 fusions (in up to 17% of intrahepatic CCAs) may predict FGFR inhibitor sensitivity. A prior phase 1 trial of the selective pan-FGFR inhibitor BGJ398 showed antitumor activity in a pt with CCA harboring an FGFR2 fusion. Methods: This ongoing phase 2, open-label study is evaluating oral BGJ398 125 mg once daily on a 3-week-on/1-week-off schedule (28-day cycle) in pts with advanced or metastatic CCA with FGFR2 fusions (n ≈ 40) or other FGFR genetic alterations (n ≤ 15) who progressed after cisplatin/gemcitabine or are cisplatin intolerant (NCT02150967). The primary endpoint is investigator-assessed overall response rate (ORR) per RECIST v1.1. Secondary endpoints include progression-free survival, best overall response (BOR), disease control rate (DCR), overall survival, safety, and pharmacokinetics. Results: As of 10 July 2015, 26 pts with CCA harboring FGFR2 fusions (n = 22) or other FGFR alterations (n = 4), pretreated with 1 to ≥ 4 prior regimens, were enrolled. Common adverse events (AEs; ≥ 20% of pts), were hyperphosphatemia (50%), fatigue (42%), constipation (38%), cough (23%), and nausea (23%). Grade 3/4 AEs occurring in ≥ 2 pts were hyper/hypophosphatemia, lipase increase, and hyponatremia. AEs were manageable, reversible, and rarely led to treatment discontinuation. Among 22 pts evaluable for BOR, 3 achieved partial response and 15 had stable disease, including 10 with tumor reductions (-41%, n = 1; -2% to -29%, n = 9). Overall DCR was 82%. As of the cutoff date, 18 pts remained on therapy, of which 13 were on for &gt; 120 days. Kaplan-Meier estimated lower limit (95% CI) of median time on study was 143 days. Conclusions: BGJ398 shows impressive anti-tumor activity and a manageable safety profile in pts with advanced FGFR-altered CCA, an indication of high unmet medical need. Updated data including additional responses post data cutoff will be presented. Clinical trial information: NCT02150967.
Role of Second Stem Cell Transplant in Patients with Amyloidosis Who Are Refractory or Relapsing.
Authors: Morie Abraham Gertz, Martha Q. Lacy, Angela Dispenzieri, Suzanne R. Hayman, Shaji K. Kumar, Stephen M. Ansell, Michelle A. Elliott, Dennis A. Gastineau, David J. Inwards, Patrick B. Johnston, Ivana N. Micallef, Luis F. Porrata, Mark R. Litzow
Journal: Blood (2005)
P3.06-003 SARON: Stereotactic Ablative Radiotherapy for Oligometastatic Non-Small Cell Lung Cancer (NSCLC). A UK Randomized Phase III Trial
Authors: Yenting Ngai, Gerard Hanna, John Conibear, Nicholas Counsell, Laura Hughes, Laura Farrelly, David Landau
Journal: Journal of Thoracic Oncology (2017)
P3.03-058 A Retrospective Evaluation of 64 Hospitalised Malignant Pleural Mesothelioma (MPM) Patients
Authors: Aida Ustamujić, Vesna Čukić, Elmedina Ćatović-Pećanac, Dina Dizdarević-Špago, Irma Sladić
Journal: Journal of Thoracic Oncology (2017)
Effect of Bortezomib on the Autonomic Nervous System.
Authors: Roberto Crocchiolo, Stefania Ferrari, Valeria Calbi, Magda Marcatti, Elena Guggiari, Paolo Servida, Massimo Bernardi, Ubaldo Del Carro, Chiara Bonini, Moreno Tresoldi, Jacopo Peccatori, Fabio Ciceri, Maria Grazia Natali Sora
Journal: Blood (2006)
P3.03-002 Inducible Changes in Cell Morphology and Gene Expression Reflecting the Histological Subtypes of Mesothelioma
Authors: Karin Schelch, Christna Wagner, Elisabeth Lang, Mir Hoda, Harald Janovjak, Ruby Lin, Walter Berger, Walter Klepetko, Nico Van Zandwijk, Glen Reid, Michael Grusch
Journal: Journal of Thoracic Oncology (2017)
PUB015 The Use of Immunohistochemistry Improves the Diagnosis of SCLC. An International Reproducibility Study in a Demanding Set of Cases
Authors: Erik Thunnissen, Alain Borczuk, Douglas Flieder, Birgit Witte, Mary Beth Beasley, Jin-Haeng Chung, Sanja Dacic, Sylvie Lantuejoul, Prudence Russell, Michael Den Bakker, Johan Botling, Elisabeth Brambilla, Erienne De Cuba, Kim Geisinger, Kenzo Hiroshima, Alberto Marchevsky, Yuko Minami, Andre Moreira, Andrew Nicholson, Akihiko Yoshida, Ming Tsao, Arne Warth, Edwina Duhig, Gang Chen, Yoshihiro Matsuno, William Travis, Kelly Butnor, Wendy Cooper, Mari Mino-Kenudson, Noriko Motoi, Claudia Polari, Giuseppe Pelosi, Keith Kerr, Yuichi Ishikawa, Reinhard Buettner, Naoto Keino, Yasushi Yatabe, Masayuki Noguchi
Journal: Journal of Thoracic Oncology (2017)
Enucleation of Human Erythroblasts Is a Process of Asymmetric Cytokinesis.
Authors: Miwa Hebiguchi, Makoto Hirokawa, Yong-Mei Guo, Yoshinari Kawabata, Atsushi Komatsuda, Takehiko Sasaki, Yuichi Takakuwa, Ken-ichi Sawada
Journal: Blood (2006)
NCI Common Toxicity Criteria and Mortality After Chemotherapy for Acute Myeloid Leukemia (AML)
Authors: Joshua R. Veatch, Ravinder K Sandhu, Kathleen Shannon-Dorcy, John M. Pagel, Pamela S. Becker, Stephen Petersdorf, Frederick R. Appelbaum, Elihu H. Estey
Journal: Blood (2012)
血栓吸引カテーテル(Oasis)とPCPSにより救命し得た院内発症肺塞栓症の一例
Authors: 芹川威, 角田修, 森卓, 村井映, 後藤英一, 土屋芳弘, 朔啓二郎, 芝野竜一, 岩隈昭夫
Journal: Circulation (2002)
Echocardiographic evaluation of pulmonary arterial hypertension in patients with progressive systemic sclerosis and related syndromes.
Authors: Ichiro Murata, Hidetoshi Kihara, Satoshi Shinohara, Koji Ito
Journal: Circulation (1992)

In order to evaluate the usefulness of echocardiography in detection and characterization of pulmonary arterial hypertension (PAH) in scleroderma patients, we performed M-mode, two-dimensional, and Doppler echocardiography in 71 patients with progressive systemic sclerosis (PSS) and related syndromes: mixed connective tissue disease (MCTD) and overlap syndromes. We estimated systolic pressure gradients across the tricuspid valve from the peak velocity of tricuspid regurgitation (TR) by color-flow guided continuous wave Doppler. TR velocities of analyzable quality for gradient estimation were obtained in 28 patients (39%), of whom 12 showed PAH (peak TR velocity≥2.5 m/sec). In comparison, analyzable TR was recorded in 19 (35%) of 55 patients with left-sided cardiac disease. None of the 12 with Doppler-estimated PAH showed left ventricular dilatation or decreased fractional shortening by M-mode and two-dimensional measurements. Nonsimultaneous cardiac catheterization con-firmed PAH in 8 of 9 with Doppler-estimated PAH and in 3 of 12 without analyzable TR who had hemodynamic study. Doppler-estimated right ventricular systolic pressures (RVSP) correlated well with catheterization-measured pulmonary arterial systolic pressures (PASP) (<0.01). Our results indicate that Doppler echocardiography is useful in detecting subclinical PAH and estimating PASP in patients with collagen vascular disease. The results of pulmonary function studies suggest that PAH in MCTD is mainly caused by pulmonary vasculopathy.
S18 A working definition and natural history of ‘minimal’ ild
Authors: R Ross Browne, A Mathur, A Marshal, PA McFarlane, GA Stewart, J Sharkey, G Ritchie, M Jones, JT Murchison, N Hirani
Journal: Thorax (2016)

<h3>Background</h3> High resolution computed tomography (HRCT) scanning is able to detect abnormalities consistent with interstitial lung disease (ILD). However, if only a small proportion of lung is affected, radiologists variously report this as 'minimal', 'minor' or 'early' ILD. There is no definition of what constitutes 'minimal' ILD and the natural history of these patients is not known. <h3>Aims</h3> To define 'minimal' ILD, test observer agreement with this definition and describe the characteristics and survival of these patients. <h3>Hypothesis</h3> Minimal ILD can be defined by subjective quantification and has a benign course. <h3>Methods</h3> Between 01.01.2002 and 31.12.2014 the Edinburgh Lung Fibrosis Database was prospectively populated with data for 1450 consecutively presenting patients with ILD. Of these, 56 were identified as presenting with 'minimal' disease according to HRCT. Three radiologists participated in a modified Delphi exercise and agreed on a definition of 'minimal' ILD. A sample (n = 38) of HRCT scans was provided to test inter- and intra-observer agreement according to this definition using Fleiss' Kappa statistics. Survival was assessed using Kaplan-Meier curves. <h3>Results</h3> The Delphi exercise resulted in 'minimal' disease being defined as ILD involving &lt;5% of the total lung volume and/or &lt;10% of the lung peripheries. Using this definition, inter-observer and intra-observer agreement was moderate (kappa 0.42 and 0.58 respectively). Of the 56 subjects originally deemed as 'minimal' ILD, 48 were unanimously described as minimal disease by post-definition criteria. One subject was biopsied (consensus after biopsy, unclassifiable). Forty-seven subjects were not biopsied and none met ATS/ERS consensus criteria for diagnosing IPF. Most subjects had 'unclassifiable' disease, but the working diagnoses were; IPF or other fibrotic idiopathic interstitial pneumonia (IIP) (n = 34), IIP without fibrosis (n = 7) and connective-tissue disease associated ILD (n = 7). The median age was 69yrs, 56% were male and 23% had never smoked. The mean (SD) %pred lung function was; FEV<sub>1</sub> 91.8% (19), VC 101% (18) TCO 62% (19). The median survival was 11.6 years, and all deaths (n = 12) were attributable to respiratory disease. <h3>Summary</h3> Defining 'minimal' ILD is feasible and there was moderate radiological agreement. Minimal ILD is relatively benign, but the associated mortality was of respiratory cause.
Absolute Quantification of Mutant T315I BCR-ABL Transcripts At 6 Months Identifies Imatinib Resistant CML Patients with a Low Probability to Achieve MMR After 12 Months on Second Line Tyrosine Kinase Therapy
Authors: Thoralf Lange, Thomas Ernst, Markus Pfirrmann, Jacqueline Maier, Martin C. Müller, Franz Gruber, Dietger Niederwieser, Andreas Hochhaus
Journal: Blood (2011)
Farnesyl Transferase Inhibitor (Tipifarnib, Zarnestra; Z) in Combination with Standard Chemotherapy with Idarubicin (Ida) and Cytarabine (ara-C) for Patients (pts) with Newly Diagnosed Acute Myeloid Leukemia (AML) or High-Risk Myelodysplastic Syndrome (MDS).
Authors: Ricardo H. Alvarez, Hagop Kantarjian, Guillermo Garcia-Manero, Zeev Estrov, Farhad Ravandi-Kashani, Srdan Verstovsek, Francis Giles, Susan O’Brien, Charles Asa Koller, Stefan Faderl, Deborah Thomas, John J. Wright, Jorge Cortes
Journal: Blood (2006)
P126 Insufficient allergy diagnostics in severe asthmatic patients in germany
Authors: JS Schreiber, CM Mailaender
Journal: Thorax (2016)

<h3>Introduction</h3> Proper evaluation of the allergic sensitizations is inevitable in treating severe asthma. Besides seasonal allergens, perennial aeroallergens have to be considered. However, within the German reimbursement system testing of only 8 allergens per quarter is reimbursed by health insurances, and thus, analyses of relevant allergens beyond the 8 common ones is often not done. <h3>Purpose</h3> The aim of this ongoing project is to gain data on sensitizations towards 35 perennial aeroallergens in severe asthmatic patients, in which no allergen could be detected in previous testing and who are thus considered non-atopic. <h3>Methods</h3> 35 locally common perennial aeroallergens (mites, fungi, animal epithelia, insects) are tested via Immulite® (specific IgE in blood) in 600 severe asthmatic patients in Germany who had negative results in previous allergen testing by either Skin Prick Test or analyses of specific IgE. Furthermore, total IgE levels are determined and a general anamnesis is documented including historical allergen testing, comorbidities, symptoms, exposure to allergens etc. <h3>Results</h3> In an interims analysis, 56.1% of 214 patients demonstrated at least one sensitisation towards a perennial aeroallergen despite they were considered non-atopic before. The most common sensitizations were found towards Rhizopus nigricans (16.8%), Aspergillus fumigatus (15.9%), Cat dander (11.1%), Dermatophagoides farina (10.7%) and Dog dander (9.9%). 84.2% of patients were (partly) uncontrolled according to GINA classification of asthma control and 51.7% had ≥2 exacerbations in the past 12 months. These results indicate a lack in diagnostics of perennial aeroallergens in severe asthmatic patients in Germany. The correct ascertainment of the allergic status is crucial to make optimal treatment decisions for the asthmatic patient.
In Vivo Analysis of the Anti-Leukemic Activity of Alpha-Tocopherol in Acute Promyelocytic Leukemia.
Authors: Rodrigo S. Abreu e Lima, Ana Silvia G. Silva, Priscila S. Scheucher, Rodrigo A. Panepucci, Rodrigo Proto-Siqueira, Guilherme Augusto F. Santos, Hamilton Luiz G. Teixeira, Fabiano P. Saggioro, Roberto P. Falcao, Eduardo M. Rego
Journal: Blood (2006)
HLA-DRB1 Analysis in Hairy B-Cell Lymphoproliferative Disorder (HBLD): A Japanese Type of Benign Persistent Polyclonal B-Cell Lymphocytosis.
Authors: Hirotaka Nakahashi, Masamitsu Karasawa, Yoko Hashimoto, Hiroyuki Irisawa, Akihiko Yokohama, Takayuki Saitoh, Hiroshi Handa, Takafumi Matsushima, Hirokazu Murakami, Norifumi Tsukamoto, Yosihisa Nojima
Journal: Blood (2006)
Single Cell Genotyping of Inv(16) AML in CBL Mutated Clonal Hematopoiesis Characterizes Clonal Architecture and Evolution of Exome Sequencing-Identified Mutations in the Protein Tyrosine Phosphatase Ptprt and Other Genes
Authors: Christoph Niemöller, Sabine Bleul, Nadja Blagitko-Dorfs, Christine Greil, Kenichi Yoshida, Rainer Claus, Dietmar Pfeifer, Seishi Ogawa, Michael Lübbert, Heiko Becker
Journal: Blood (2015)
P1.03-025 Serum KL-6 Levels in Patients with Lung Cancer
Authors: Tatsuya Yoshimasu, Mitsumasa Kawago, Yoshimitsu Hirai, Shoji Oura, Yozo Kokawa, Miwako Miyasaka, Mariko Honda, Yuka Aoishi, Aya Oku, Yoshiharu Nishimura
Journal: Journal of Thoracic Oncology (2017)
P2.07-008 Victorian Comprehensive Cancer Centre Lung Cancer Clinical Audit: Collecting the UK National Lung Cancer Audit data from hospitals in Australia
Authors: Linda Mileshkin, Tamsin Waterhouse, Hannah Cross, Mary Duffy, Paula Nelson, Mark Shaw, Paul Mitchell, Tim Akhurst, Louis Irving, Matthew Conron, Melissa Moore, Jennifer Philip, Stephen Barnett, Philip Antippa, James Bartlett, Jon Emery, Jennifer Byrne, Jim Bishop
Journal: Journal of Thoracic Oncology (2017)
Outcome of Upfront Autologous Peripheral Blood Stem Cell Transplantation for Multiple Myeloma in African American Versus Non Non-African American Patients.
Authors: Yasser Khaled, Ginny Kamboj, Vijaya Donthireddy, Hazem Hnaide, Nancy Oja-Tebbe, George Divine, Nalini Janakiraman
Journal: Blood (2005)
P2.06-041 TeleNursing: A Thoracic Surgery Nursing Initiative Aimed at Decreasing Hospital Readmissions and Increasing Patient Satisfaction
Authors: Melissa Culligan, Joseph Friedberg, Lindsey Black, Seantrese Wimbush, Colleen Norton, Whitney Burrows, Shamus Carr, James Donahue, Marc Zubrow
Journal: Journal of Thoracic Oncology (2017)
Plasma thromboxane B2, 6-KETO PGF1.ALPHA. and cyclic nucleotides levels as related to treadmill exercise test in patients with ischemic heart disease.
Authors: Michiyoshi Yajima, Shuzo Nomura, Kenichi Namba, Masaaki Sekine, Toshiaki Hosoka, Fujio Numano
Journal: Circulation (1985)

Plasma prostanoids and levels of cyclic nucleotides were studied in forty-nine outpatients with precordial pains and subjected to the treadmill exercise test. Blood samples were drawn before, immediately after and 30 minutes after exercise, from antecubital veins. Plasma TXB2, 6-keto PGF1 alpha, cyclic AMP and cyclic GMP levels were measured by radioimmunoassay. The results of exercise tests were evaluated according to the treadmill exercise score (TES) of Hollenberg et al. Patients were divided into two groups; those with TES (-) with ischemic findings in exercise and those with TES (+) with normal exercise response. There were no differences in TXB2 levels between the two groups before exercise. Immediately after exercise statistically significant differences in TXB2 levels were present between the two groups. There were increased levels in the TES (-) group and decreased levels in the TES (+) group (p less than 0.01). Although the 6-keto PGF1 alpha levels were the same between the two groups before exercise, 6-keto PGF1 alpha levels in the TES (+) group increased significantly immediately after exercise. Similar changes were noted in the case of cyclic nucleotides, and the differences increased immediately after exercise. We conclude that high responses of cyclic nucleotides and PGI2 are required to counteract increases in levels of TXA2 and diminution of these responses may be an important phenomenon involved in the physiological status of ischemic heart disease.
Quality of Life in Elderly Patients with Acute Myeloid Leukemia Undergoing Induction Chemotherapy
Authors: Esther Natalie Oliva, Prassede Salutari, Anna Candoni, Alessandra Freyrie, Debora Capelli, Francesco Di Raimondo, Antonio Volpe, Nicola Cascavilla, Paolo Di Bartolomeo, Erica Simeone, Agostino Cortelezzi, Pietro Leoni, Pellegrino Musto, Fortunato Morabito, Pasquale Niscola, Natale Ranieri, Irene Santacaterina, Antonio Giovanni Marino, Patrizia Cufari, Caterina Alati, Francesca Ronco
Journal: Blood (2015)