Update in Nephrology and Hypertension: Evidence Published in 2015
Authors: Aldo J. Peixoto
Journal: Annals of Internal Medicine (2016)

Updates3 May 2016Update in Nephrology and Hypertension: Evidence Published in 2015Aldo J. Peixoto, MDAldo J. Peixoto, MDFrom Yale University School of Medicine, New Haven, Connecticut.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/M16-0243 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail This update highlights 11 important studies with relevance to general internists' care of patients with kidney disease and hypertension. Topics include optimal blood pressure (BP) targets; resistant hypertension; new agents to manage hyperkalemia; new agents to treat hyperphosphatemia and anemia in patients receiving dialysis; and lack of efficacy of immunosuppressive therapy added to optimal medical care for immunoglobulin A (IgA) nephropathy. I identified studies by using ACP JournalWise and by reviewing studies presented at the major nephrology and hypertension meetings in 2015.HypertensionA Lower Systolic BP Target Provides Greater Cardiovascular Risk Protection Than the Conventional Target in Patients With ...References1. Cushman WC, Evans GW, Byington RP, Goff DC, Grimm RH, Cutler JA, et al; ACCORD Study Group. Effects of intensive blood-pressure control in type 2 diabetes mellitus. N Engl J Med. 2010;362:1575-85. [PMID: 20228401] doi:10.1056/NEJMoa1001286 CrossrefMedlineGoogle Scholar2. Perkovic V, Rodgers A. Redefining blood-pressure targets—SPRINT starts the marathon [Editorial]. N Engl J Med. 2015;373:2175-8. [PMID: 26551394] doi:10.1056/NEJMe1513301 CrossrefMedlineGoogle Scholar3. American College of Obstetricians and Gynecologists. Hypertension in pregnancy. Report of the American College of Obstetricians and Gynecologists Task Force on Hypertension in Pregnancy. Obstet Gynecol. 2013;122:1122-31. [PMID: 24150027] doi:10.1097/01.AOG.0000437382.03963.88 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Yale University School of Medicine, New Haven, Connecticut.Disclosures: Dr. Peixoto was a member of the steering committee of EnligHTN IV, an industry-sponsored trial of renal denervation in resistant hypertension, and received honoraria from St. Jude Medical as part of this activity and as a member of its advisory board. The form can also be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M16-0243.Editors' Disclosures: Christine Laine, MD, MPH, Editor in Chief, reports that she has no financial relationships or interests to disclose. Darren B. Taichman, MD, PhD, Executive Deputy Editor, reports that he has no financial relationships or interests to disclose. Cynthia D. Mulrow, MD, MSc, Senior Deputy Editor, reports that she has no relationships or interests to disclose. Deborah Cotton, MD, MPH, Deputy Editor, reports that she has no financial relationships or interest to disclose. Jaya K. Rao, MD, MHS, Deputy Editor, reports that she has stock holdings/options in Eli Lilly and Pfizer. Sankey V. Williams, MD, Deputy Editor, reports that he has no financial relationships or interests to disclose. Catharine B. Stack, PhD, MS, Deputy Editor for Statistics, reports that she has stock holdings in Pfizer.Corresponding Author: Aldo J. Peixoto, MD, Section of Nephrology, Yale University School of Medicine, Boardman 114 (Nephrology), 330 Cedar Street, New Haven, CT 06520; e-mail, aldo.[email protected]edu.Author Contributions: Conception and design: A.J. Peixoto.Drafting of the article: A.J. Peixoto.Critical revision for important intellectual content: A.J. Peixoto.Final approval of the article: A.J. Peixoto. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAssociation between furosemide administration and outcomes in critically ill patients with acute kidney injuryPerioperative Renoprotection: Clinical Implications 3 May 2016Volume 164, Issue 9Page: W42-W47KeywordsACE inhibitorsAngiotensin receptor blockerDenervationEstimated glomerular filtration rateHypertensionPotassiumProteinuriaRenal diseasesRenal failureResistant hypertension ePublished: 3 May 2016 Issue Published: 3 May 2016 Copyright & PermissionsCopyright © 2016 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...