Migraine
Authors: E. Anne MacGregor
Journal: Annals of Internal Medicine (2013)

In the ClinicNovember 5, 2013MigraineE. Anne MacGregor, MB, MD, Deborah Cotton, MD, MPH, Darren, MD, PhD Taichman, MD, PhD, and Sankey Williams, MDE. Anne MacGregor, MB, MD, Deborah Cotton, MD, MPH, Darren, MD, PhD Taichman, MD, PhD, and Sankey Williams, MDAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-159-9-201311050-01005 SectionsSupplemental MaterialAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail More than 90% of patients who have recurrent headache on presentation to primary care offices or emergency departments have migraine. Migraine affects approximately 13% of adults in the United States and is associated with high socioeconomic and personal impact. In the Global Burden of Disease Survey 2010, it was ranked as the third most prevalent disorder and seventh-highest specific cause of disability worldwide.Risk and PreventionWho is at risk for migraine headache?Studies have shown that the tendency to develop migraines can be inherited. If one parent has migraine headaches, there is a 40% chance that their children will also ...References1. Michel P, Dartigues JF, Henry P, et al. Validity of the International Headache Society criteria for migraine. GRIM. Groupe de Recherche Interdisciplinaire sur la Migraine. Neuroepidemiology. 1993;12:51-7. [PMID: 8327023] Google Scholar2. Rodriguez-Valverde V, Sarabia JM, Gonzalez-Gay MA, et al. Risk factors and predictive models of giant cell arteritis in polymyalgia rheumatica. Am J Med. 1997;102:331-6. [PMID: 9217613] Google Scholar3. Huston KA, Hunder GG, Lie JT, et al. Temporal arteritis: a 25-year epidemiologic, clinical, and pathologic study. Ann Intern Med. 1978;88:162-7. [PMID: 626444] Google Scholar4. Frishberg BM. The utility of neuroimaging in the evaluation of headache in patients with normal neurologic examinations. Neurology. 1994;44:1191-7. [PMID: 8035914] Google Scholar5. Frishberg BM, Rosenberg JH, Matchar DB, et al. Evidence-based guidelines for migraine headache: neuroimaging in patients with nonacute headache. US Headache Consortium; 2000. www.aan.com Google Scholar6. Gronseth GS, Greenberg MK. The utility of the electroencephalogram in the evaluation of patients presenting with headache: a review of the literature. Neurology. 1995;45:1263-7. [PMID: 7617180] Google Scholar7. Facchinetti F, Allais G, Nappi RE, et al. Migraine is a risk factor for hypertensive disorders in pregnancy: a prospective cohort study. Cephalalgia. 2009;29:286-92. [PMID: 19220309] Google Scholar8. American College of Obstetricians and Gynecologists. ACOG Committee Opinion No. 299. Obstet Gynecol. 2004;104:647-51 [PMID: 15339791] Google Scholar9. Peatfield RC. Relationships between food, wine, and beer-precipitated migrainous headaches. Headache. 1995;35:355-7. [PMID:7635722] Google Scholar10. Van den Bergh V, Amery WK, Waelkens J. Trigger factors in migraine: a study conducted by the Belgian Migraine Society. Headache. 1987;27:191-6. [PMID: 3597073] Google Scholar11. Egger J, Carter CM, Wilson J, et al. Is migraine food allergy? A double-blind controlled trial of oligoantigenic diet treatment. Lancet. 1983;2:865-9. [PMID: 6137694] Google Scholar12. Mansfield LE, Vaughan TR, Waller SF, et al. Food allergy and adult migraine: double-blind and mediator confirmation of an allergic etiology. Ann Allergy. 1985;55:126-9. [PMID: 4025956] Google Scholar13. Holroyd KA, Penzien DB. Pharmacological versus non-pharmacological prophylaxis of recurrent migraine headache: a meta-analytic review of clinical trials. Pain. 1990;42:1-13. [PMID: 2146583] Google Scholar14. Lipton RB, Baggish JS, Stewart WF, et al. Efficacy and safety of acetaminophen in the treatment of migraine: results of a randomized, double-blind, placebo-controlled, population-based study. Arch Intern Med. 2000;160:3486-92. [PMID:11112243] Google Scholar15. Kirthi V, Derry S, Moore RA, McQuay HJ. Aspirin with or without an antiemetic for acute migraine headaches in adults. Cochrane Database Syst Rev 2010; 4: CD008041 Google Scholar16. Goldstein J, Hoffman HD, Armellino JJ, et al. Treatment of severe, disabling migraine attacks in an over-the-counter population of migraine sufferers: results from three randomized, placebo-controlled studies of the combination of acetaminophen, aspirin, and caffeine. Cephalalgia. 1999;19:684-91 Google Scholar17. Rabbie R, Derry S, Moore RA, et al. Ibuprofen with or without an antiemetic for acute migraine headaches in adults. Cochrane Database Syst Rev. 2010;(10):CD008039. Google Scholar18. Tfelt-Hansen P, Henry P, Mulder LJ, Scheldewaert RG, et al. The effectiveness of combined oral lysine acetylsalicylate and metoclopramide compared with oral sumatriptan for migraine. Lancet. 1995;346:923-6. [PMID: 7564725] Google Scholar19. Friedman BW, Mulvey L, Esses D, et al. Metoclopramide for acute migraine: a dose-finding randomized clinical trial. Annals of emergency medicine. 2011;57:475-82. [PMID: 21227540] Google Scholar20. Lipton RB, Stewart WF, Stone AM, et al. Stratified care vs step care strategies for migraine: the Disability in Strategies of Care (DISC) Study: A randomized trial. JAMA. 2000;284:2599-605. [PMID: 11086366] Google Scholar21. Tfelt-Hansen P. Efficacy and adverse events of subcutaneous, oral, and intranasal sumatriptan used for migraine treatment: a systematic review based on number needed to treat. Cephalalgia. 1998;18:532-8. [PMID: 9827244] Google Scholar22. Ferrari MD, Roon KI, Lipton RB, et al. Oral triptans (serotonin 5-HT(1B/1D) agonists) in acute migraine treatment: a meta-analysis of 53 trials. Lancet. 2001;358:1668-75. [PMID: 11728541] Google Scholar23. Oldman AD, Smith LA, McQuay HJ, et al. Pharmacological treatments for acute migraine: quantitative systematic review. Pain. 2002;97:247-57. [PMID: 12044621] Google Scholar24. Gilman PK. Triptans, serotonin agonists, and serotonin syndrome (serotonin toxicity): a review. Headache 2010;50:264-72. [PMID:19925619] Google Scholar25. Winner P, Ricalde O, Le Force B, et al. A double-blind study of subcutaneous dihydroergotamine vs subcutaneous sumatriptan in the treatment of acute migraine. Arch Neurol. 1996;53:180-4. [PMID: 8639069] Google Scholar26. Colman I, Brown MD, Innes GD, et al. Parenteral dihydroergotamine for acute migraine headache: a systematic review of the literature. Ann Emerg Med. 2005;45:393-401. [PMID: 15795718] Google Scholar27. Tfelt-Hansen P, Saxena PR, Dahlof C, et al. Ergotamine in the acute treatment of migraine: a review and European consensus. Brain. 2000;123:9-18. [PMID: 10611116] Google Scholar28. Colman I, Brown MD, Innes GD, et al. Parenteral metoclopramide for acute migraine: meta-analysis of randomised controlled trials. BMJ. 2004;329:1369-73. [PMID: 1555040] Google Scholar29. Friedman BW, Corbo J, Lipton RB, et al. A trial of metoclopramide vs sumatriptan for the emergency department treatment of migraines. Neurology. 2005;64:463-8. [PMID: 15699376] Google Scholar30. Kelly AM, Walcynski T, Gunn B. The relative efficacy of phenothiazines for the treatment of acute migraine: a meta-analysis. Headache. 2009;49:1324-32. [PMID: 19496829] Google Scholar31. Holroyd KA, Cordingley GE, Pingel JD, et al. Enhancing the effectiveness of abortive therapy: a controlled evaluation of self-management training. Headache. 1989;29:148-53. [PMID: 2496052] Google Scholar32. Morey SS. Guidelines on migraine: part 4. General principles of preventive therapy. Am Fam Physician. 2000;62:2359-60, 2363. [PMID: 11126860] Google Scholar33. Silberstein S, Holland S, Freitag F, et al. Evidence-based guideline update: Pharmacologic treatment for episodic migraine prevention in adults: Report of the Quality Standards Subcommittee of the American Academy of Neurology and the American Headache Society. Neurology 2012;78:13374 [PMID: 3335452]) Correction published in Neurology 2013;80:871 Google Scholar34. Silberstein SD, Elkind AH, Schreiber C, Keywood C. A randomized trial of frovatriptan for the intermittent prevention of menstrual migraine. Neurology. 2004;63:261-9. [PMID: 15277618] Google Scholar35. Holland S, Silberstein SD, Freitag F, et al. Evidence-based guideline update: NSAIDs and other complementary treatments for episodic migraine prevention in adults: report of the Quality Standards Subcommittee of the American Academy of Neurology and the American Headache Society. Neurology 2012;78:1346-53. [PMID: 3335449] Google Scholar36. Dodick DW, Turkel CC, DeGryse RE et al. OnabotulinumtoxinA for treatment of chronic migraine: pooled results from the double-blind, randomized, placebo-controlled phases of the PREEMPT clinical program. Headache 2010; 50: 921-936 [PMID: 20487038] Google Scholar37. Diener HC, Bussone G, Van Oene JC et al. Topiramate reduces headache days in chronic migraine: a randomized, double-blind, placebo-controlled study. Cephalalgia 2007; 27: 814-823[PMID: 17441971]) Google Scholar38. Granella F, Sances G, Zanferrari C, et al. Migraine without aura and reproductive life events: a clinical epidemiological study in 1300 women. Headache. 1993;33:385-9. [PMID: 8376100] Google Scholar39. Adeney KL, Williams MA, Miller RS, et al. Risk of preeclampsia in relation to maternal history of migraine headaches. J Matern Fetal Neonatal Med 2005;18:167-72. [PMID: 16272039] Google Scholar40. Scharff L, Marcus DA, Turk DC. Maintenance of effects in the nonmedical treatment of headaches during pregnancy. Headache. 1996;36:285-90. [PMID: 8682668] Google Scholar41. Duong S, Bozzo P, Nordeng H, Einarson A. Safety of triptans for migraine headaches during pregnancy and breastfeeding. Can Fam Physician. 2010;56:537-9. [PMID: 20547518] Google Scholar42. Olesen C, Steffensen FH, Sorensen HT, et al. Pregnancy outcome following prescription for sumatriptan. Headache. 2000;40:20-4. [PMID: 10759898] Google Scholar43. Gallagher RM. Emergency treatment of intractable migraine. Headache.1986;26:74-5. [PMID: 3957657] Google Scholar44. Saper JR, Lake AE III, Madden SF, et al. Comprehensive/tertiary care for headache: a 6-month outcome study. Headache. 1999;39:249-63. [PMID: 9747046]. Google Scholar45. Facchinetti F, Allais G, Nappi RE, et al. Migraine is a risk factor for hypertensive disorders in pregnancy: a prospective cohort study. Cephalalgia. 2009;29:286-92. [PMID: 19220309] Google Scholar46. Holroyd KA, Cordingley GE, Pingel JD, et al. Enhancing the effectiveness of abortive therapy: a controlled evaluation of self-management training. Headache. 1989;29:148-53. [PMID: 2496052] Google Scholar47. Hoodin F, Brines BJ, Lake AE 3rd, et al. Behavioral self-management in an inpatient headache treatment unit: increasing adherence and relationship to changes in affective distress. Headache. 2000;40:377-83. [PMID: 10849032] Google Scholar Author, Article, and Disclosure InformationAffiliations: Funding source: American College of Physicians.Potential conflicts of interest: Dr. MacGregor, ACP Contributing Author, has disclosed no conflicts of interest. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics November 5, 2013Volume 159, Issue 9Page: ITC5-1KeywordsAnalgesicsArteriesCaffeineDrug therapyDrugsEpilepsyExerciseGiant cellsHeadachesMigraineNSAIDsNauseaNeuroimagingOpiatesOpioidsSecondary headachesSleepSodiumTreatment guidelinesVomiting ePublished: 5 November 2013 Issue Published: November 5, 2013 CopyrightCopyright © 2013 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...