tbuckley/cabot-search huggingface dataset:
Immunophenotypic Characterization of the Bladder Mucosa Infiltrating Lymphocytes after Intravesical BCG Treatment for Superficial Bladder Carcinoma
Authors: C Boccafoschi, F Montefiore, M Pavesi, M Pastormerlo, S Annoscia, C Lozzi, P G Betta
Journal: European Urology (1992)
Observations on a Leukemic Cell Variant in Mice
Authors: Stewart R. Humphreys, John M. Venditti, Nathan Mantel, Abraham Goldin
Journal: JNCI Journal of the National Cancer Institute (1956)

Observations on a Leukemic Cell Variant in Mice Get access Stewart R. Humphreys, Stewart R. Humphreys Laboratory of Chemical Pharmacology and Biometry and Epidemiology Branch, National Cancer Institute,2Bethesda, Maryland Search for other works by this author on: Oxford Academic PubMed Google Scholar John M. Venditti, John M. Venditti Laboratory of Chemical Pharmacology and Biometry and Epidemiology Branch, National Cancer Institute,2Bethesda, Maryland Search for other works by this author on: Oxford Academic PubMed Google Scholar Nathan Mantel, Nathan Mantel Laboratory of Chemical Pharmacology and Biometry and Epidemiology Branch, National Cancer Institute,2Bethesda, Maryland Search for other works by this author on: Oxford Academic PubMed Google Scholar Abraham Goldin Abraham Goldin Laboratory of Chemical Pharmacology and Biometry and Epidemiology Branch, National Cancer Institute,2Bethesda, Maryland Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 17, Issue 4, October 1956, Pages 447–457, https://doi.org/10.1093/jnci/17.4.447 Published: 01 October 1956 Article history Received: 11 May 1956 Published: 01 October 1956
A Decade of Active Surveillance in the PRIAS Study: An Update and Evaluation of the Criteria Used to Recommend a Switch to Active Treatment
Authors: Leonard P. Bokhorst, Riccardo Valdagni, Antti Rannikko, Yoshiyuki Kakehi, Tom Pickles, Chris H. Bangma, Monique J. Roobol
Journal: European Urology (2016)
MB-35DIFFERENT IMPACTS ON EPISODIC MEMORY OF CHILDHOOD MEDULLOBLASTOMA TREATMENTS
Authors: Elodie Doger de Spéville, Christelle Dufour, Catherine Chiron, Virginie Kieffer, Audrey Longaud, Jacques Grill, Dominique Valteau-Couanet, Robert Kaddouch, Lucie Hertz-Pannier, Marion Noulhiane
Journal: Neuro-Oncology (2016)
Attitudes toward issues in psychiatry among third-year residents: a brief survey
Authors: W Coryell, R D Wetzel
Journal: American Journal of Psychiatry (1978)

The authors surveyed 378 third-year psychiatric residents on their attitudes toward psychiatric training, forms of psychotherapy, and the medical model; their treatment preferences for 4 given psychiatric disorders; and their career plans. Correlation coefficients and analysis of variance indicated clustering of attitudes along a dynamic-biological continuum, with medical education and experience with drug therapy rated highest of the training aspects and personal analysis or psychotherapy, training in psychoanalysis, and research rated lowest.
Failure of Eugenol and Heat to Potentiate Gastric Tumor Induction by 20-Methylcholanthrene in Mice&lt;xref ref-type="fn" rid="fn1"&gt;&lt;sup&gt;2&lt;/sup&gt;&lt;/xref&gt;
Authors: Claude R. Hitchcock, M. D.
Journal: JNCI Journal of the National Cancer Institute (1952)

Journal Article Failure of Eugenol and Heat to Potentiate Gastric Tumor Induction by 20-Methylcholanthrene in Mice Get access Claude R. Hitchcock, M. D. Claude R. Hitchcock, M. D. Department of Surgery, University of Minnesota Medical School, Minneapolis, Minn. Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 12, Issue 4, February 1952, Pages 723–733, https://doi.org/10.1093/jnci/12.4.723 Published: 01 February 1952 Article history Received: 06 September 1951 Published: 01 February 1952
Baseline characteristics and survival outcomes of advanced gastric cancer patients treated with two or more lines of chemotherapy: results from a large Italian cohort
Authors: L. Ferrari, C. Fontanella, M. Uccello, G. Pasquini, S. Bozzarelli, R. Filippi, M. Imperatori, D. Ferrara, G. Tomasello, O. Brunetti, F. Pietrantonio, L. Bellu, E.S. Lutrino, D. Melisi, L. Antonuzzo, G. Musettini, S. Cordio, C. Vivaldi, L. Rimassa, G. Aprile
Journal: Annals of Oncology (2015)
SIOP (International Society of Paediatric Oncology) and the management of Wilms' tumor.
Authors: G J D'Angio
Journal: Journal of Clinical Oncology (1983)

Article Tools Article Tools OPTIONS & TOOLS Export Citation Track Citation Add To Favorites Rights & Permissions COMPANION ARTICLES No companion articles ARTICLE CITATION DOI: 10.1200/JCO.1983.1.10.595 Journal of Clinical Oncology - published online before print September 21, 2016 PMID: 6321672 SIOP (International Society of Paediatric Oncology) and the management of Wilms' tumor. G J D'AngioxG J D'AngioSearch for articles by this author https://doi.org/10.1200/JCO.1983.1.10.595 PDF "SIOP (International Society of Paediatric Oncology) and the management of Wilms' tumor.." Journal of Clinical Oncology, 1(10), pp. 595–596© 1983 by American Society of Clinical Oncology
Abstract 166: High Dose of Epinephrine Administered During Cardiopulmonary Resuscitation Leads to Greater Oxidative Stress Following Resuscitation From Cardiac Arrest
Authors: Francesca Fumagalli, Giuseppe Ristagno, Giovanni Li Volti, Rosa Santangelo, Ilaria Russo, Roberto Latini
Journal: Circulation (2010)

Introduction: Optimal dose of epinephrine to be used during CPR is controversial. Nevertheless, epinephrine has been recognized to increase ischemic injury. Oxidative stress that follows ROSC is an...
Urinary Tract Infections in General Practice
Authors: W Probst
Journal: JAMA (1963)

Urinary tract infections are a frequent problem in ambulatory practices. According to the localization of the infection and to complicating factors we differentiate between various syndromes with different clinical presentations. Relevant diagnostic criteria are a bacteriuria of greater than or equal to 100 organisms par millilitre or a pyuria of greater than or equal to 5 leukocytes per high power field. For acute cystitis, a treatment for three days is recommended. Cotrimoxazole or quinolones are effective drugs, which are more and more recommended for the treatment of acute pyelonephritis, too.
HG-66BRAIN STEM GLIOMA NATIONAL REGISTRY: PILOT PROGRAM
Authors: Anne Elizabeth Murray Cota, Marta Zapata Tarres, Farina Esther Arreguín González, Alma Edith Benito Resendiz, Martha Margarita Velázquez Aviña, Luis Enrique Juárez Villegas, Ana Maria Niembro Zuñiga, Roberto Rivera Luna
Journal: Neuro-Oncology (2016)
PNR-19CRIBIFORM NEUROEPITHELIAL TUMOR (CRINET) ARISING FROM THE LATERAL VENTRICLE: A CASE OF RARITY AND FAVORABLE OUTCOME
Authors: Kellie B. Haworth, Michael A. Arnold, Christopher R. Pierson, Suzanne L. Scott, Jonathan L. Finlay, Randal S. Olshefski
Journal: Neuro-Oncology (2016)
Abstract 2438: Local Bipolar Atrial Electrogram Monitoring during the Extensive Encircling Pulmonary Vein Isolation: Implications of the ``QS Pattern” in the Local Bipolar Atrial Electrogram after the Ablation
Authors: Kiyoshi Otomo, Hiroshi Taniguchi, Yasutoshi Nagata, Kikuya Uno, Yoshito Iesaka
Journal: Circulation (2007)

BACKGROUND During the extensive encircling pulmonary vein (PV) isolation (EEPVI) for atrial fibrillation (AF), it is crucial to recognize whether or not a sufficient lesion was created by an ablation in each ablation site. The local electrogram (EG)-based criteria to predict a sufficient local lesion formation, however, remain to be established. This study was performed to define local EG-based criteria for the local lesion formation during the EEPVI for AF. METHODS Among 31 patients (pts) with AF who had successful EEPVI during coronary sinus pacing, bipolar local EGs at 2271 ablation sites (73+/-19 sites/pt, posterior wall (PW) of the left atrium (LA)/anterior LA-PV junction=976/1295 sites) before and after energy delivery were reviewed. In EEPVI, ipsilateral PVs, antral regions and parts of the PW of the LA were isolated as a whole by linear ablation at the PW of the LA and semi-linear ablation at the anterior LA-PV junction. Each energy application was performed with a temperature controlled mode (maximal temperature: 55 degrees Celsius, maximal output: 35 watt) and duration of 25 to 35 seconds. RESULTS After the ablation, all PVs, antral regions and parts of the PW of the LA were successfully isolated in all 31 pts (duration of each energy application: 31+/-3 sec/site, total energy application time: 37+/-10 min/pt). After the effective ablation at each site, the local EGs exhibited predominant reduction in the amplitude of positive deflection (Ap) as compared to that of negative deflection (An) (% reduction in Ap vs An: 91+/-10 vs 30+/-59%; p&lt;0.01, Ap/An ratio before vs after ablation: 2.3+/-3.4 vs 0.3+/-0.1; p&lt;0.01) as well as total amplitude reduction (67+/-22%) and EG widening (57+/-43%), and the morphology of the local EG changed to the ``QS” or ``rS” patterns. At 25 sites without those morphological changes, residual LA-PV conduction gaps were observed and additional ablations were required to achieve a complete EEPVI in 20 pts. CONCLUSION We propose that a morphological change of local EGs to ``QS” or ``rS” patterns with predominant attenuation of positive deflection of local EGs can reflect sufficient local lesion formation and can be one of the practical endpoints for energy delivery at each ablation site during the EEPVI.
Ascertaining Costs and Benefits of Colonoscopy More Difficult Than the Procedure Itself
Authors: Michael F. Cannon
Journal: JAMA Internal Medicine (2016)

My grandfather died of colorectal cancer when my mother was 13 years old, a catastrophic event that tore his family apart.1 When I was a child and even a young adult, his death seemed to me more an abstraction than a tragedy that unfolded slowly, devastating people I love.
LMI-18MULTIDISCIPLINARY APPROACH TO PERFORMING AWAKE CRANIOTOMY FOR TUMOR RESECTION IN PEDIATRIC PATIENTS. A CASE-REPORT FROM A PEDIATRIC-ONCOLOGIC HOSPITAL IN MEXICO
Authors: Rafael Ruvalcaba-Sanchez, Gabriela Escamilla-Asiain, Nelly Martinez-Barreto, Carolina Nuñez-Valencia, Berenice Ruelas-Leon, Karla Reyes-Salgado, Vanesa Peralta-Velazquez
Journal: Neuro-Oncology (2016)
Is the "live patient" interview on the boards necessary?
Authors: J A Talbott
Journal: American Journal of Psychiatry (1983)

Study of American Board of Psychiatry certification examinations over a 2-year period revealed differences between audiovisual and "live patient" interview grades. Of 2,236 psychiatrists examined in psychiatry, 1,367 (61%) received concordant scores on their audiovisual and "live patient" examination hours and 1,165 (52%) received identical grades. Agreement about pass/fail decisions was even higher (80%). Where scores were not identical, two out of three candidates scored higher on the audiovisual section, prompting the conclusion that the two examination formats may test somewhat different skills or carry a different weight in the judgment of most examiners. It is therefore reasonable to conclude that these differences must continue to be tested for.
Quality of Life and Satisfaction with Outcome among Prostate-Cancer Survivors
Authors: Wadih Arap
Journal: New England Journal of Medicine (2008)

To the Editor: The quality of life is an important consideration in treatment for prostate cancer. The study by Sanda et al. (March 20 issue) 1 provides valuable information regarding this aspect of treatment. Unfortunately, the abstract highlights two of the least relevant observations made in this study. First, although the authors show that hormone therapy diminishes the quality of life, class I evidence supports its use in intermediaterisk and high-risk patients receiving radio therapy. 2-5 Highlighting a small effect on the quality of life, given the survival advantages, seems inappropriate. Second, the decision to offer nervesparing radical prostatectomy is usually dictated more by efforts to control disease than by qualityof-life concerns. Finally, as shown in Figure 1 of the article, at 24 months, the mean sexual score for patients undergoing prostatectomy was similar to that for patients receiving radiotherapy or brachytherapy, even though the patients in the prostatectomy group started with a higher mean sexual score and were 5 to 10 years younger. The relative decline in sexual function was significantly worse in the patients who underwent prostatectomy, even with the use of nerve-sparing techniques. This finding should have been emphasized in the abstract and should be considered in making informed treatment decisions.
CR-13RADIATION-INDUCED GLIOBLASTOMA MULTIFORME WITHIN 4 YEARS OF CRANIAL IRRADIATION FOR PAEDIATRIC CRANIOPHARYNGIOMA - CASE REPORT AND REVIEW OF THE LITERATURE
Authors: Noelle Cullinan, Jane Cryan, Catriona O'Sullivan, Patricia Daly, Michael Farrell, Michael Capra, Jane Pears, Cormac Owens
Journal: Neuro-Oncology (2016)
Guidelines of the French Society of Digestive Endoscopy: Endoscopic Mucosectomy
Authors: M Greff, L Palazzo, T H Ponchon, J M Canard
Journal: Endoscopy (2001)

Since 1998 the Council of the French Society of Digestive Endoscopy has published standards for good practice in endoscopy. At present these recommendations appear to be the best way of arriving at optimal practice. Written by a group of experts and corrected by an even larger expert group, they are regularly updated in written form in order to help with decision making.
Ovarian Tumorigenesis Following Intrasplenic Transplantation of Ovaries from Weanling, Young Adult, and Senile Mice&lt;xref ref-type="fn" rid="fn1"&gt;&lt;sup&gt;2&lt;/sup&gt;&lt;/xref&gt;
Authors: Michael Klein
Journal: JNCI Journal of the National Cancer Institute (1952)

Ovarian Tumorigenesis Following Intrasplenic Transplantation of Ovaries from Weanling, Young Adult, and Senile Mice2 Michael Klein Michael Klein Research Fellow National Cancer Institute4Bethesda, Md. Search for other works by this author on: Oxford Academic PubMed Google Scholar 3Present address: Cancer Research Laboratory, University of Florida, Gainesville, Fla. 4National Institutes of Health Public Health Service, Federal Security Agency. Author Notes JNCI: Journal of the National Cancer Institute, Volume 12, Issue 4, February 1952, Pages 877–881, https://doi.org/10.1093/jnci/12.4.877 Published: 01 February 1952 Article history Received: 18 October 1951 Published: 01 February 1952
IL-15 promotes activation and expansion of CD8+ T cells in HIV-1 infection
Authors: Souheil-Antoine Younes, Michael L. Freeman, Joseph C. Mudd, Carey L. Shive, Arnold Reynaldi, Soumya Panigrahi, Jacob D. Estes, Claire Deleage, Carissa Lucero, Jodi Anderson, Timothy W. Schacker, Miles P. Davenport, Joseph M. McCune, Peter W. Hunt, Sulggi A. Lee, Sergio Serrano-Villar, Robert L. Debernardo, Jeffrey M. Jacobson, David H. Canaday, Rafick-Pierre Sekaly, Benigno Rodriguez, Scott F. Sieg, Michael M. Lederman
Journal: Journal of Clinical Investigation (2016)

In HIV-1-infected patients, increased numbers of circulating CD8+ T cells are linked to increased risk of morbidity and mortality. Here, we identified a bystander mechanism that promotes CD8 T cell activation and expansion in untreated HIV-1-infected patients. Compared with healthy controls, untreated HIV-1-infected patients have an increased population of proliferating, granzyme B+, CD8+ T cells in circulation. Vβ expression and deep sequencing of CDR3 revealed that in untreated HIV-1 infection, cycling memory CD8 T cells possess a broad T cell repertoire that reflects the repertoire of the resting population. This suggests that cycling is driven by bystander activation, rather than specific antigen exposure. Treatment of peripheral blood mononuclear cells with IL-15 induced a cycling, granzyme B+ phenotype in CD8+ T cells. Moreover, elevated IL-15 expression in the lymph nodes of untreated HIV-1-infected patients correlated with circulating CD8+ T cell counts and was normalized in these patients following antiretroviral therapy. Together, these results suggest that IL-15 drives bystander activation of CD8+ T cells, which predicts disease progression in untreated HIV-1-infected patients and suggests that elevated IL-15 may also drive CD8+ T cell expansion that is linked to increased morbidity and mortality in treated patients.
CD38 expression and complement inhibitors affect response and resistance to daratumumab therapy in myeloma
Authors: Inger S. Nijhof, Tineke Casneuf, Jeroen van Velzen, Berris van Kessel, Amy E. Axel, Khaja Syed, Richard W. J. Groen, Mark van Duin, Pieter Sonneveld, Monique C. Minnema, Sonja Zweegman, Christopher Chiu, Andries C. Bloem, Tuna Mutis, Henk M. Lokhorst, A. Kate Sasser, Niels W. C. J. van de Donk
Journal: Blood (2016)
<i>In Utero</i> and Early-Life Exposure to Ambient Air Toxics and Childhood Brain Tumors: A Population-Based Case–Control Study in California, USA
Authors: Ondine S. von Ehrenstein, Julia E. Heck, Andrew S. Park, Myles Cockburn, Loraine Escobedo, Beate Ritz
Journal: Environmental Health Perspectives (2015)

Little is known about the influence of environmental factors on the etiology of childhood brain tumors.We examined risks for brain tumors in children after prenatal and infant exposure to monitored ambient air toxics.We ascertained all cases of medulloblastoma, central nervous system primitive neuroectodermal tumor (PNET), and astrocytoma before 6 years of age diagnosed in 1990-2007 from the California Cancer Registry and selected controls randomly from birth rolls matched by birth year. Exposures to air toxics during pregnancy/infancy for 43 PNET, 34 medulloblastoma, and 106 astrocytoma cases and 30,569 controls living within 5 mi of a monitor were determined. With factor analysis we assessed the correlational structures of 26 probable carcinogenic toxics, and estimated odds ratios by brain tumor type in logistic regression models.PNETs (≤ 38 cases) were positively associated with interquartile range (IQR) increases in prenatal exposure to acetaldehyde [odds ratio (OR) = 2.30; 95% CI: 1.44, 3.67], 1,3-butadiene (OR = 2.23; 95% CI: 1.28, 3.88), benzene, and toluene; and with IQR increases in exposure during the first year of life to ortho-dichlorobenzene (OR = 3.27; 95% CI: 1.17, 9.14), 1,3-butadiene (OR = 3.15; 95% CI: 1.57, 6.32), and benzene. All exposures except ortho-dichlorobenzene loaded on the same factor. Medulloblastoma (≤ 30 cases) was associated with prenatal exposure to polycyclic aromatic hydrocarbons (PAHs combined: OR = 1.44; 95% CI: 1.15, 1.80). Exposures to lead and some PAHs during the first year of life were positively associated with astrocytoma, but the confidence intervals included the null value (e.g., for lead, OR = 1.40; 95% CI: 0.97, 2.03).Our data suggest that in utero and infancy exposures to air toxics generated by industrial and road traffic sources may increase the risk of PNET and medulloblastoma, with limited support for increased risks for astrocytoma in children up to age 6.von Ehrenstein OS, Heck JE, Park AS, Cockburn M, Escobedo L, Ritz B. 2016. In Utero and early-life exposure to ambient air toxics and childhood brain tumors: a population-based case-control study in California, USA. Environ Health Perspect 124:1093-1099; http://dx.doi.org/10.1289/ehp.1408582.
P17.12 * FAMILIAL GLIOBLASTOMA
Authors: R. M. Buhl, M. Kalkan
Journal: Neuro-Oncology (2014)

We report a rare case of familial glioblastoma. A 76 year old female patient presented with seizures and headache. MRI of her brain showed a glioblastoma in her right temporal lobe. It was removed surgically and histopathological examination confirmed the suspected diagnosis of glioblastoma (WHO Grad IV). The postoperative course was uneventful and she received radio- and chemotherapy. Her daughter died at the age of 48 years due to a glioblastoma of the corpus callosum. This tumor was stereotactically biosied in another neurosurgical department. Neuropathological examination also showed a glioblastoma (WHO Grad IV).
Men With HIV Age Faster According to DNA Methylation Study
Authors: Julie A. Jacob
Journal: JAMA (2016)

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Massive Hemorrhage into an Adrenal Pheochromocytoma
Authors: David J. Lehman, Jack Rosof
Journal: New England Journal of Medicine (1956)

IRREVERSIBLE shock and sudden death due to massive unilateral adrenal hemorrhage without sepsis is a unique, often unrecognized syndrome, death usually being ascribed to some other catastrophic illness. The following case illustrates the diagnostic difficulties that may be encountered.Case ReportD.P., a 50-year-old woman, awakened suddenly at 2 a.m. on June 10, 1955, complaining of a severe, localized pain in the right lumbar region associated with nausea, vomiting and extreme weakness. She had gone to sleep at 11 p.m., apparently in good health. Her husband stated that she had always been well; the menopause had occurred at the age . . .