tbuckley/cabot-search huggingface dataset:
Case 21-1967
Authors: Stephen M. Krane, Benjamin Castleman
Journal: New England Journal of Medicine (1967)

Presentation of CaseA fifty-six-year-old woman was admitted to the hospital because of fever.Eighteen years previously she had a febrile illness for a week, and a year later she had "virus pneumonia," which resolved promptly but was followed by persistent fever for approximately five months. Six months before admission dental extractions were performed. Three months later there was the onset of a mild illness characterized by generalized myalgia, chilly sensations, a headache and elevation of the temperature to 102°F. An injection of penicillin was administered, together with several capsules of an antibiotic that provoked mild nausea and was promptly . . .
ABCG2 Is Expressed in a Small Population of Circulating CLL B-Cells Characterized by Expression of Self-Renewal and Early B-Cell Development Genes and Resistance to Therapy
Authors: Grzegorz S. Nowakowski, Xiaosheng Wu, Jennifer L. Abrahamzon, Renee Tschumper, Neil E. Kay, Diane F. Jelinek
Journal: Blood (2008)
Comments On: Some Aspects of the Morphology of the Bittner Virus
Authors: J Ito
Journal: JNCI Journal of the National Cancer Institute (1970)

Journal Article Comments On: Some Aspects of the Morphology of the Bittner Virus Get access Jishu Ito, M.D., Ph.D. Jishu Ito, M.D., Ph.D. Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 45, Issue 5, November 1970, Pages 1065–1066, https://doi.org/10.1093/jnci/45.5.1065 Published: 01 November 1970
ALLERGY IN ANIMALS
Authors: B Pelet
Journal: JAMA (1934)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The question remains: oncology and primary care.
Authors: R F Holcombe
Journal: Journal of Clinical Oncology (1997)

Article Tools Article Tools OPTIONS & TOOLS Export Citation Track Citation Add To Favorites Rights & Permissions COMPANION ARTICLES No companion articles ARTICLE CITATION DOI: 10.1200/JCO.1997.15.3.1285 Journal of Clinical Oncology - published online before print September 21, 2016 PMID: 9060575 The question remains: oncology and primary care. R F HolcombexR F HolcombeSearch for articles by this author https://doi.org/10.1200/JCO.1997.15.3.1285 PDF "The question remains: oncology and primary care.." Journal of Clinical Oncology, 15(3), pp. 1285–1286© 1997 by American Society of Clinical Oncology
Meningitis B vaccine should not be given to babies, committee says
Authors: Anne Gulland
Journal: BMJ (2016)

The Joint Committee on Vaccination and Immunisation (JCVI) has rejected a call for the meningitis B vaccination programme to be extended to all children under the age of two.

The committee said that there was not enough stock of the vaccine to be able to extend the programme to children aged 12 to 23 months. The vaccination was introduced into the routine immunisation programme for babies under the age of one last year.

The minutes of the JCVI’s June committee meeting, published online on 13 July, said that, while “wider use of …
Herpesviruses From the Owl Monkey (&lt;italic&gt;Aotus trivirgafus&lt;/italic&gt;)&lt;xref ref-type="fn" rid="FN1"&gt;2&lt;/xref&gt;&lt;xref ref-type="fn" rid="FN2"&gt;3&lt;/xref&gt;
Authors: H H Barahona, M D Daniel, L V Meléndez, N W King, C E Fraser, F G García
Journal: JNCI Journal of the National Cancer Institute (1972)
The Birth, and Evolution, of Percutaneous Coronary Interventions
Authors: Patrick W. Serruys, John D. Rutherford
Journal: Circulation (2016)

Dr Rutherford asks: When you first heard that Andreas Grüentzig had successfully performed a transluminal coronary dilation in September 1977, what were your thoughts?Did it seem a sustainable therapy at the time?Dr Serruys replies: In 1975 at a meeting in Frankfurt, a key opinion leader at that time, Professor Paul Lichtlen, Chief of Cardiology at Hannover, was describing during a keynote lecture a significant coronary lesion with a thin fibrous cap and a large atheromatous core; today, we call this a vulnerable plaque.He mentioned somewhat sarcastically that Dr Andreas Grüentzig had developed a procedure he believed could dilate that type of lesion.There was of course a lot of skepticism whether the procedure could be performed without major distal embolization.I went to see Andreas Grüentzig and to look at his poster.He had tied a ligature with catgut around the coronary artery of a dog, and he was using his balloon to open this artificial narrowing.Honestly, I could not foresee the future of this therapeutic approach.At that time, the Department of Cardiology in Zürich (where Grüentzig worked) was headed by 2 cardiologists, Hans Peter Krayenbühl and Wilhelm Rutishauser.Krayenbühl was not in favor of attempting the procedure, but Rutishauser was more enthusiastic about it.The famous Chief of Cardiovascular Surgery, Dr Åke Senning, told the Board of the hospital that he would help Andreas and be present in the cardiac catheterization laboratory to back up a potential catastrophe.The story is that when Andreas deflated the balloon and the gradient disappeared, Senning left the laboratory, without even looking at the angiogram, convinced the result was good.In 1978, Grüentzig reported successful dilation of an 85% left anterior descending coronary stenosis by PTCA in a 38-year-old man with severe angina and theThe Birth, and Evolution,
Are there ‘new’ and ‘old’ ways to track infectious diseases hazards and outbreaks?
Authors: J  C Desenclos
Journal: Eurosurveillance (2006)

In May 2005 the World Health Assembly approved an innovative and ambitious revision of the International Health Regulations, known as IHR(2005), in order to detect and control, in a timely manner, all public health events that may have a serious international impact. It represents a dramatic move from administrative notification by Member States (MS) to the World Health Organization (WHO) of cases of a limited list of diseases to a systematic analysis of health events of international concern, infectious or not [1]. The analysis of the public health events will take into account severity, unexpectedness, potential for international spread, and interference with international movement of people and goods. National focal points are to be identified in each MS to interact with WHO. The philosophy behind the new IHR is to promote early dialogue between MS and WHO, leading to early mutual risk assessment of events which may not necessarily have to be notified, depending on the results of the assessment and measures taken. WHO can also use informal sources to detect earlier events of international concern and then, together with the national focal point, conduct verification, risk assessment and implement appropriate measures.
Pre-Operatively Determined Prognostic Factors in Metastatic Renal Cell Carcinoma
Authors: Noriomi Miyao, Toshiro Oda, Masanori Shigyou, Kouichi Takeda, Naoya Masumori, Atsushi Takahashi, Hiroshi Kitamura, Taiji Tsukamoto
Journal: European Urology (1997)
The children's psychiatric hospital unit in the community: I. Concept and development
Authors: B J Blinder, W M Young, K R Fineman, S J Miller
Journal: American Journal of Psychiatry (1978)

The authors describe a children's mental health unit (CMHU) in a general hospital and cite the need for short- and intermediate-term children's psychiatric facilities within the community. They point out the special need for psychiatric inpatient units for the 3-13 age group and note that in their CMHU the average length of stay and patient turnover ratio compare favorably with adolescent units, which they attribute to the emphasis on diagnosis and treatment rather than long-term rehabilitation.
Deux épidémies de salmonellose à Salmonella Enteritidis lysotype 8 liées à la consommation de Cantal au lait cru, France, 2001
Authors: S Haeghebaert, P Sulem, L Deroudille, E. Vanneroy-Adenot, O Bagnis, P Bouvet, F Grimont, A Brisabois, C. Hervy, E Espié, H de Valk, V Vaillant
Journal: Eurosurveillance (2003)

Les salmonelles sont une des principales causes d'infections d'origine alimentaire dans les pays industrialises. En France, en 2001, l'incidence des salmonelloses humaines recensees par le Centre National de Reference des Salmonella et Shigella (CNRSS) etait de 21 cas pour 100 000 habitants et Salmonella serotype Enteritidis representait 39% des cas (1). Dans cet article, nous rapportons les resultats des investigations de deux epidemies communautaires de salmonellose, survenues successivement dans le sud-ouest de la France et qui etaient liees a la consommation d'un fromage au lait cru.
Cancer Center Advertising—Where Hope Meets Hype
Authors: Lisa M. Schwartz, Steven Woloshin
Journal: JAMA Internal Medicine (2016)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Internal Medicine HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Internal Medicine journal
Optimized Mealtime Insulin Dosing for Fat and Protein in Type 1 Diabetes: Application of a Model-Based Approach to Derive Insulin Doses for Open-Loop Diabetes Management
Authors: Kirstine J. Bell, Elena Toschi, Garry M. Steil, Howard A. Wolpert
Journal: Diabetes Care (2016)

OBJECTIVE To determine insulin dose adjustments required for coverage of high-fat, high-protein (HFHP) meals in type 1 diabetes (T1D). RESEARCH DESIGN AND METHODS Ten adults with T1D received low-fat, low-protein (LFLP) and HFHP meals with identical carbohydrate content, covered with identical insulin doses. On subsequent occasions, subjects repeated the HFHP meal with an adaptive model-predictive insulin bolus until target postprandial glycemic control was achieved. RESULTS With the same insulin dose, the HFHP increased the glucose incremental area under the curve over twofold (13,320 ± 2,960 vs. 27,092 ± 1,709 mg/dL ⋅ min; P = 0.0013). To achieve target glucose control following the HFHP, 65% more insulin was required (range 17%–124%) with a 30%/70% split over 2.4 h. CONCLUSIONS This study demonstrates that insulin dose calculations need to consider meal composition in addition to carbohydrate content and provides the foundation for new insulin-dosing algorithms to cover meals of varying macronutrient composition.
How Do Organs Maintain Local Blood Control?
Authors: S A GLADSTONE
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Mechanism of Symptomatic Improvement After Percutaneous Therapy for Secondary Mitral Regurgitation
Authors: Caroline M. Van De Heyning, Philippe B. Bertrand, Philippe Debonnaire, Catherine De Maeyer, Pieter M. Vandervoort, Patrick Coussement, Bernard P. Paelinck, Dina De Bock, Christiaan J. Vrints, Marc J. Claeys
Journal: Journal of the American College of Cardiology (2016)
Epigenetic Signatures of Salivary Gland Inflammation in Sjögren's Syndrome
Authors: Michael B. Cole, Hong Quach, Diana Quach, Alice Baker, Kimberly E. Taylor, Lisa F. Barcellos, Lindsey A. Criswell
Journal: Arthritis & Rheumatology (2016)

Sjögren's syndrome (SS) is a complex multisystem autoimmune disease that results in progressive destruction of the exocrine glands. The purpose of this study was to characterize epigenetic changes in affected gland tissue and describe the relationship of these changes to known inflammatory processes.A genome-wide DNA methylation study was performed on human labial salivary gland (LSG) biopsy samples obtained from 28 female members of the Sjögren's International Collaborative Clinical Alliance (SICCA) Registry. Gland tissue was methylotyped using the Illumina HumanMethylation450 BeadChip platform, followed by rigorous probe-filtering and data-normalization procedures.A genome-wide case-control study of 26 of the 28 subjects revealed 7,820 differentially methylated positions (DMPs) associated with disease status, including 5,699 hypomethylated and 2,121 hypermethylated DMPs. Further analysis identified 57 genes that were enriched for DMPs in their respective promoters; many are involved in immune response, including 2 previously established SS genetic risk loci. Bioinformatics analysis highlighted an extended region of hypomethylation surrounding PSMB8 and TAP1, consistent with an increased frequency of antigen-presenting cells in LSG tissue from the SS cases. Transcription factor motif enrichment analysis revealed the specific nature of the genome-wide methylation differences, demonstrating colocalization of SS-associated DMPs with stress- and immune response-related motifs.Our findings underscore the utility of CpG methylotyping as an independent probe of active disease processes in SS, offering unique insights into the composition of disease-relevant tissue. Methylation profiling implicated several genes and pathways previously thought to be involved in disease-related processes, as well as a number of new candidates.
Treatment of Thromboembolic Disease
Authors: N FOWLER, J McGUIRE
Journal: New England Journal of Medicine (1949)

account for the findings of Coon et al. (1981) in using atropine following adrenaline for the treatment of pre-hospital cardiac arrests.There is thus good physiological support for the concept that consequent upon an episode of asystole there are times when a return to sinus rhythm is prevented by parasympathetic overactivity.It would seem logical, therefore, to administer atropine in these circumstances.
Phase II trial of 177Lutetium radiolabeled anti-prostate-specific membrane antigen (PSMA) monoclonal antibody J591 (177Lu- J591) in patients (pts) with metastatic androgen-independent prostate cancer (AIPC)
Authors: N. H. Bander, D. M. Nanus, M. I. Milowsky, M. J. Morris, S. Jeske, S. Vallabhajosula, S. J. Goldsmith
Journal: Journal of Clinical Oncology (2007)

15523 Background: A phase 1 trial of 177Lu-J591 in pts with metastatic AIPC demonstrated acceptable toxicity, excellent targeting of metastatic sites and biologic activity. Methods: Pts with progressive, metastatic AIPC receive one dose of 177Lu-J591 in two- cohorts: cohort 1 (65 mCi/m 2 ), 15 pts; cohort 2: (70 mCi/m 2 ), 17 pts. The primary endpoint is PSA and/or measurable disease response; secondary endpoint is toxicity. A 177Lu-J591 imaging study is done to confirm tumor targeting. Results: 21 pts (8 chemo-naive), median age 73, have been treated to date, 15 in cohort 1, 6 in cohort 2. Two pts with bone-only metastases achieved PSA declines of &gt;50%. One had an 87% PSA decline lasting 126 days with resolution of bone pain. A 2nd pt has a PSA decline of 58% that continues without progression at 6 mo post-rx. PSA stabilization (&lt;25% PSA rise above baseline) occurred in an additional 9 pts (43%), 7 through wk 8 (1 of whom is still under follow-up) and 2 pts through wk 12. Of 7 pts with measurable disease, 6 have had post-rx CT scans completed, 3 were stable, 3 progressed. In these pts with measurable disease, PSA was more likely to diagnose progression, with only 1 stable and 5 progressed by PSA criteria. Platelet nadir &lt;20 x 10e9/L occurred in 6 pts, 3 of whom required platelet transfusions (mean = 2). 17/19 evaluable pts recovered normal platelet counts; the remaining 2 pts had rapidly progressive disease, 1 of whom had biopsy confirmed marrow replacement by tumor. Neutropenia &lt;/= 0.5 x 10e9/L occurred in 4 pts, 2 of whom received brief rx with growth factors. All 19 evaluable pts had normal neutrophil recovery. No significant drug-related non-hematologic toxicity has occurred. Targeting of known sites of PC metastases has been observed in all pts. Conclusions: Single dose 177Lu-J591 demonstrates anti-tumor activity in pts with progressive, metastatic AIPC with reversible myelosuppression. Accrual is continuing. [Table: see text]
US court smoothes way for abortion clinic blockades.
Authors: McBride G
Journal: BMJ (1993)

The US Supreme Court has ruled that a civil rights law of 1871 cannot be used to protect abortion clinics from sometimes violent blockades by anti-abortionist.  Federal judges have used this law to order US marshalls to protect abortion clinics and women seeking abortions from disruptive protests when local law authorities have been outnumbered or unwilling to halt blockades.  The law was originally enacted to prevent the Klu Klux Klan from using mob violence to prevent newly emancipated black people from exercising their constitutional rights.  This case came to the Supreme Court on appeal from a lower court which had held that Operation Rescue had violated the part of the law banning conspiracies to deprive any person or class of persons of the equal protection of the laws or of equal privileges and immunities.   In a 6-3 opinion with Justice Scalia writing for the majority the court ruled that the old civil rights law cannot be applied to the clinic blockades because there are common and respectable reasons for opposing [abortion] other than hatred of or condescension toward    women as a class as  evident from the fact that men and women are on both sides of the issue   .  Dissenting Justice Stevens wrote that the demonstrators conduct is designed to deny every woman the opportunity to exercise a constitutional right that only women possess    It present a striking contemporary example of the kind of zealous politically motivated lawless conduct that led to the enactment of the Klu Klux Klan Act in 1871.  Congressional action may negate the impact of the courts decision.  The case was remanded to the lower court to determine whether an injunction against Operation Rescues blockade of a Virginia clinic can be continued on the basis of state law.
Early versus late irradiation in small-cell lung cancer.
Authors: R M Auchter
Journal: Journal of Clinical Oncology (1998)

Article Tools Article Tools OPTIONS & TOOLS Export Citation Track Citation Add To Favorites Rights & Permissions COMPANION ARTICLES No companion articles ARTICLE CITATION DOI: 10.1200/JCO.1998.16.3.1235 Journal of Clinical Oncology - published online before print September 21, 2016 PMID: 9508215 Early versus late irradiation in small-cell lung cancer. R M AuchterxR M AuchterSearch for articles by this author https://doi.org/10.1200/JCO.1998.16.3.1235 First Page PDF © 1998 by American Society of Clinical Oncology
Percutaneous compression plate versus dynamic hip screw for treatment of intertrochanteric hip fractures: A overview of systematic reviews and update meta-analysis of randomized controlled trials
Authors: Haitao Long, Zhangyuan Lin, Bangbao Lu, Ruibo Zhao, Buhua Sun, Liang Cheng, Shushan Zhao, Yong Zhu
Journal: International Journal of Surgery (2016)
Abstract 2340: Atrial Mechanical Function Using Left Atrial Pressure Waveform Analysis in Persistent and Paroxysmal Atrial Fibrillation Patients
Authors: Zhongwei Cheng, Ronald Lo, Anurag Gupta, Marco Perez, Paul Zei, Henry H Hsia, Mintu Turakhia, Amin Al-Ahmad, Paul J Wang
Journal: Circulation (2009)

Background: Atrial fibrillation (AF) adversely impacts left atrial (LA) mechanical function, which may reflect the underlying disease process or atrial remodeling. LA pressure measurements at the t...
Erratum: Detection of colonic dysplasia in vivo using a targeted heptapeptide and confocal microendoscopy
Authors: Pei-Lin Hsiung, Jonathan Hardy, Shai Friedland, Roy Soetikno, Christine B Du, Amy P Wu, Peyman Sahbaie, James M Crawford, Anson W Lowe, Christopher H Contag, Thomas D Wang
Journal: Nature Medicine (2008)
Elevated Binding of Chronic Lymphocytic Leukemia Antibody to a Subset of Apoptotic Cells with Exposed Non-Muscle Myosin Heavy Chain IIA Correlates with Poor Patient Outcome.
Authors: Charles C. Chu, Rosa Catera, Lu Zhang, Briana M. Agagnina, Sebastien Didier, Jonathan E. Kolitz, Steven L. Allen, Kanti R. Rai, Nicholas Chiorazzi
Journal: Blood (2009)
Pilonidal sinus: clinical and ultrasonographic response to topical resorcinol 15%
Authors: B. Encabo, J.C. Pascual, D. Romero, R.F. Ruiz de Apodaca, J. Selva, G.B.E. Jemec
Journal: British Journal of Dermatology (2016)

pilonidal sinus (PS) is a common recurrent disease, often inflamed, usually located on sacral area, and causing high levels of morbidity. The incidence is estimated around 26 cases per 100,000, and it is more common in men (2:1). PS usually develops during the 2nd - 3rd decade of life.1

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