tbuckley/cabot-search huggingface dataset:
P255 Reproducibility of lung clearance index (LCI) in clinically stable adults with mild cystic fibrosis (CF)
Authors: AR Horsley, A Shawcross, M Oladapo, A Maitra, S Cunningham, AM Jones, J Smith, F Gilchrist
Journal: Thorax (2016)

<h3>Background</h3> In order for lung clearance index (LCI) to be a clinically useful measurement, a better understanding is required of short-term variability. LCI-SEARCH is a longitudinal study in children and adults with CF, with LCI measured at each clinical review using a portable closed-circuit wash-in system (www.lci-search.com). Here we report initial LCI repeatability from the adult cohort. <h3>Methods</h3> LCI measurements were performed in triplicate using a closed-circuit wash-in method (Horsley <i>et al</i>.<i> ERJ open</i>). The most recent paired LCI measurements were included providing they were within 6 months of each other, the patient was deemed clinically stable by a physician and the patient scored &lt;2 on a 4 point respiratory symptom score. Repeatability was assessed by Bland-Altman analysis. <h3>Results</h3> Of 40 CF adults, paired data were available on 21 (7 subjects had completed only 1 assessment, 1 withdrawn, 11 clinically unstable). These 21 subjects (14 male) completed a median of 5 LCI measurements each (range 2–11), a median of 84 (range 42–189) days apart. Mean age was 28 yrs, mean FEV1 82% predicted, 11 pancreatic sufficient, 11 had never had pseudomonas infection. Mean (SD) LCI at visit 1 was 8.68 (2.96) vs 8.73 (2.81) at visit 2 (p = ns). Median coefficient of variation for LCI was 3.9% (visit 1) and 4.2% (visit 2). Mean change in LCI between visits was 0.05 (1% of baseline LCI). 95% limits of agreement (LOA) were −1.1 (−13.7)% to 1.0 (11.6)% of baseline LCI. In this very mild cohort, 7 patients had normal LCI (&lt;7); exclusion of these did not substantially alter LOA (−13.9 to 13.1%). There was greater variability in FRC: mean bias −1.5% of baseline (LOA 30 to −33%). <h3>Conclusions</h3> Even in this very mild cohort of CF adults, patients are frequently unwell or more symptomatic at routine review. Within-visit repeatability was good, and similar to previous reports. When clinically stable, LCI variability over a period of up to 6months was approximately ± 10%. Addition of more adult as well as paediatric data to this assessment will widen the applicability of these confidence intervals.
OA11.05 A Phase 2 Study of Cabozantinib for Patients with Advanced RET-Rearranged Lung Cancers
Authors: Alexander Drilon, Romel Somwar, Roger Smith, Lukas Delasos, Melanie Albano, Martine Van Voorthuyson, Lu Wang, Natasha Rekhtman, Andy Ni, Andrew Plodkowski, Michelle Ginsberg, Gregory Riely, Charles Rudin, Marc Ladanyi, Mark Kris
Journal: Journal of Thoracic Oncology (2017)
P1.05-006 Identification of miRNAs and mRNAs Associated with Metastasis in Early-Stage Non-Small Cell Lung Cancer (NSCLC)
Authors: Shirley Tam, Nhu-An Pham, Shingo Sakashita, Ethan Kaufman, Melania Pintilie, Ni Liu, Geoffrey Liu, Frances Shepherd, Ming Tsao
Journal: Journal of Thoracic Oncology (2017)
Cytoreductive Regimen Containing Ranimustine (MCNU),Carboplatin, Etoposide and Cyclophosphamide (MCEC) Before Autologous Peripheral Blood Stem Cell Transplantation for Relapsed or Refractory Lymphoma
Authors: Yoshitaka Asakura, Ryuji Tanosaki, Sung-Won Kim, Teruhisa Azuma, Saiko Kurosawa, Kimikazu Yakushijin, Dai Maruyama, Shin-ichiro Mori, Takahiro Fukuda, Takashi Watanabe, Yukio Kobayashi, Kensei Tobinai, Yoichi Takaue
Journal: Blood (2008)
P101 Structured Holistic Nursing Assessment (HNA) in Buckinghamshire Healthcare Trust (BHT) for lung cancer &amp; mesothelioma patients: process and findings
Authors: J Mowforth, H Steiner, A Prasad
Journal: Thorax (2016)

<h3>Aim</h3> Lung cancer and mesothelioma patients have complex needs. Without a structured process of screening and assessment these can go undetected. Structured screening and assessment needs considered planning. Our experience of screening and assessment of the holistic needs for lung cancer and mesothelioma patients in BHT is described. <h3>Method</h3> All BHT lung cancer and mesothelioma patients are invited to be screened post diagnosis using the Distress Thermometer and Needs checklist (Brennan <i>et al</i> 2012).<sup>1</sup> Participation rates vary between 55–65% and since 2013, 467 patients have been contacted with 265 patients participating. A database stores all HNA activity. This includes individual overall numerical score for distress (0–10), a breakdown of categories of need including physical, emotional, practical, social and spiritual. It also records specific aspects of distress within each category and where specified the top four aspects of need. <h3>Results</h3> Of the 265 respondents, 196 (74%) recorded physical problems, 145 (54%) recorded emotional issues with worry, fear, sadness and depression sited as the top four aspects. In addition 63 (24%) reported practical problems e.g. money and transport, 53 (20%) family problems, and 32 (12%) spiritual concerns. Overall tiredness, breathing, getting around and worry are the top four needs recorded by our patients. Of all patients screened to date a third score Distress above 5, these patients are prioritised for a nurse led clinic. <h3>Conclusion</h3> Through screening issues often not disclosed in doctor led clinics are identified and addressed leading to involvement of other professionals and services. Screening patients away from the clinical setting enables greater disclosure, prevents bias or influence on scoring and allows complex needs that might go undetected to be explored. The process enables care to be patient focused and proactive in managing complex needs before crisis events occur. <h3>Reference</h3> Brennan J, <i>et al</i>. Refinement of the distress management problem list as the basis for a holistic therapeutic conversation among UK patients with cancer. <i>Psycho-Oncology</i> 2012;<b>21</b>:1346–56.
P2.03b-041 Cerebrospinal Fluid Tumor Cells for Diagnosis of Leptomeningeal Metastases in Non-Small Cell Lung Cancer
Authors: Yang-Si Li, Ben-Yuan Jiang, Wei-Bang Guo, Zhi-Hong Chen, Zhi-Yong Chen, Xu-Chao Zhang, Jian Su, Chong-Rui Xu, Yi Long Wu
Journal: Journal of Thoracic Oncology (2017)
Abstract B33: Persistent activation of ERK and SMAD4 nuclear retention by high free fatty acids promote breast cancer metastasis
Authors: Yong Wu, Xiaoting Yu, Kruttika Bhat, Sami Dwabe, Mohammad Atefi, Jay Vadgama
Journal: Clinical Cancer Research (2017)

Abstract Obesity increases the risk of developing distant metastatic recurrence, and diminishes overall and breast cancer-specific survival; however, the mechanisms behind this correlation and relevant therapeutic targets are poorly defined. Plasma free fatty acids (FFA) levels are usually elevated in obese individuals. Here, using human breast cancer cell lines, we found that TGF-β transiently activates the extracellular signal-regulated kinase (ERK) and subsequently marks SMAD4 for phosphorylation, which facilitates SMAD4-ubiquitin specific peptidase 9, X-linked (USP9x) interaction, SMAD4 nuclear retention, SMAD3-SMAD4 complex nuclear accumulation, and stimulated TGF-β/SMAD3–mediated transcriptional activity of Twist and Snail. USP9x competitively inhibited the E3 ubiquitin-protein ligase transcriptional intermediary factor 1 γ (TIF1γ) from binding and monoubiquitinating SMAD4. This process maintained SMAD4 nuclear retention and stabilized the SMAD3/SMAD4 complex in the nucleus. Inhibition of ERK resulted in SMAD4 de-phosphorylation, USP9x-SMAD4 disassociation and SMAD4-TIF1γ interaction, which ultimately marks SMAD4 for mono-ubiquitination, leading to SMAD4 nuclear export and termination of the transcription of Twist and Snail. In addition, loss of USP9x abolished TGF-β–induced SMAD4 nuclear retention and SMAD3/SMAD4 formation, leading to inhibition of Twist and Snail expression. We also found that ERK-induced SMAD4 T277 phosphorylation and SMAD4-USP9x interaction was required for TGF-β–induced breast cancer invasion, which was attributed to SMAD3/SMAD4-dependent up-regulation of the transcription factors, Twist and Snail. Importantly, FFA further facilitates TGF-β–induced ERK activation, SMAD4 phosphorylation, SMAD4 nuclear retention and SMAD3/SMAD4 formation, thus promoting TGF-β–dependent cancer progression. Inhibition of ERK and USP9x suppressed obesity-induced metastasis. Additionally, phospho-ERK and -SMAD4 levels correlated with activated TGF-β signaling and metastasis in obese patient breast cancer specimens. Altogether, we demonstrated that USP9x promotes breast cancer invasion by promoting nuclear retention of SMAD4 and identified crosstalk between USP9x and TGF-β/ERK/SMAD4/SMAD3 pathways. Our study highlights the vital interaction of USP9x and SMAD4 for governing TGF-β signaling and dyslipidemia-induced aberrant TGF-β activation during breast cancer metastasis. Citation Format: Yong Wu, Xiaoting Yu, Kruttika Bhat, Sami Dwabe, Mohammad Atefi, Jay Vadgama. Persistent activation of ERK and SMAD4 nuclear retention by high free fatty acids promote breast cancer metastasis. [abstract]. In: Proceedings of the AACR Precision Medicine Series: Targeting the Vulnerabilities of Cancer; May 16-19, 2016; Miami, FL. Philadelphia (PA): AACR; Clin Cancer Res 2017;23(1_Suppl):Abstract nr B33.
Elucidation of B Cell Antigen Receptor Signaling by Global Phosphoproteomics Reveals Novel Signaling Pathways and Regulatory Mechanisms
Authors: Thomas Oellerich, Jasmin Corso, Michael Engelke, Daniel Stanze, He-Hsuan Hsiao, Juergen Wienands, Henning Urlaub, Hubert Serve
Journal: Blood (2012)
Demonstration of myocardial ischemia and serial assessment of left ventricular function in cardiac amyloidosis.
Authors: Tetsu Yamakado, Takeshi Nakano, Satoru Kawahira, Hirofumi Fujioka, Hideo Nishikawa, Yoshimi Uchida, Naoki Isaka, Hideo Takezawa, Ryuichi Yatani
Journal: Circulation (1987)
Leaflet Thrombosis in Surgically Explanted or Post-Mortem TAVR Valves
Authors: Fernanda M. Mangione, Tannas Jatene, Alexandra Gonçalves, Gregory A. Fishbein, Richard N. Mitchell, Marc P. Pelletier, Tsuyoshi Kaneko, Pinak B. Shah, Charles B. Nyman, Douglas Shook, Ron Blankstein, Robert F. Padera, Deepak L. Bhatt
Journal: JACC. Cardiovascular imaging (2017)
P239 Effects of tiotropium on asthma exacerbations are not explained by airway hyperresponsiveness, exhaled breath nitric oxide or airway geometry
Authors: S Jabbal, A Manoharan, BJ Lipworth
Journal: Thorax (2016)

<h3>Background</h3> Long acting muscarinic antagonists (LAMA) such as tiotropium (TIO) reduce asthma exacerbations in patients receiving inhaled corticosteroids and long-acting beta-agonists (ICS/LABA). However the mechanism for this protective action of LAMA remains unclear. <h3>Objectives</h3> To evaluate the response to indacaterol (IND) either alone in combination with tiotropium (IND/TIO) in addition to ICS on airway hyperresponsiveness (AHR), FeNO and impulse oscillometry (IOS). <h3>Methods</h3> n = 14 ICS treated asthmatic patients (Mean age 46 years, FEV1 86% predicted, R5 160% predicted, ICS 693ug/day),were randomised in cross-over fashion to receive either IND 150ug alone (ICS/LABA) or in combination with TIO 18ug once daily (ICS/LABA/LAMA) for 4 weeks with 2 week run-in and washout periods. Mannitol sensitivity (PD15) and reactivity (RDR), airway resistance (R5,R5-R20), reactance (AXE) and FeNO were measured at 24 hours after the first and last doses. <h3>Results</h3> There were significant improvements in mannitol PD15 and RDR with IND or IND/TIO vs baseline after single but not chronic dosing (Figure) . There was also a significant difference in RDR between single and chronic dosing for both treatments. R5,R5-R20 and AXE were significantly improved with both treatments compared to baseline after single and chronic dosing . There were no significant differences between treatments after chronic dosing for either mannitol or IOS . In contrast FeNO was unchanged with either treatment compared to baseline. <h3>Conclusions</h3> There were significant improvements in mannitol sensitivity and reactivity with either IND or IND/TIO after single but not chronic dosing, while FeNO remained unchanged . Airway resistance and reactance were significantly decreased to the same degree with both treatments after chronic dosing . This in turn suggests that the mechanism by which LAMA reduces exacerbations is unlikely to be related to AHR, FeNO or airway geometry.
Elderly followers of Mediterranean diet retain brain volume better, study finds
Authors: Ingrid Torjesen
Journal: BMJ (2017)

Older people who followed a Mediterranean diet retained more brain volume over three years than those who did not follow the diet so closely, a study published in Neurology has found.1

The study included 967 Scottish people in the Lothian Birth Cohort of 1936 aged around 70 without dementia, who completed a questionnaire about their eating habits. Three years later 562 participants agreed to have a magnetic resonance imaging (MRI) brain scan, and 401 returned for a second scan at about age 76.

The …
P243 Specific antibody deficiency to streptococcus pneumoniae and haemophilus influenzae in asthma and fungal disease
Authors: S Zaidi, G Tavernier, D Ryan, SJ Fowler, R Niven
Journal: Thorax (2016)

<h3>Introduction</h3> Recurrent exacerbations are a characteristic feature of uncontrolled asthma, often due to viral or bacterial infections. We have reported in a retrospective study that immune deficiency is common in asthma and correlates with reduced lung function. We set up a prospective study to determine if this predisposes to a more severe disease. <h3>Aim</h3> Our aim is to ascertain if immune deficiency is associated with a more severe disease potentially with radiological changes and clinically with low lung function and frequent exacerbations. <h3>Methods</h3> We prospectively collected data from new patients attending the regional asthma and fungal clinics. Demographics, markers of disease severity and specific antibody levels to <i>Haemophilus iInfluenzae</i> (HI), and <i>Streptococcus pneumoniae</i> (SP), were recorded. Patients with specific antibody deficiency (HI: ≤ 0.15 iu and SP: ≤ 0.35 iu to 6+ of 12 strains tested) received appropriate vaccination(s) in primary care (Pneumovax® and Meniotrix®), with repeat samples collected two months later. We also recorded blood and sputum eosinophil counts, radiological findings such as bronchiectasis and bronchial wall thickening, total IgE, smoking status, exacerbations in the last year and ITU admissions. <h3>Results</h3> 101 patients were followed up (69 asthma, 32 fungal) 67 female, mean (SD) age 53 (15) years, FEV1 69 (21.9)% predicted, ICS dose 1818 (1244) μg, and BMI 29.9 (8.9) kg/m<sup>2</sup>. Specific antibody levels and responses to vaccination are presented in Figure 1. Immune deficiency at baseline and post vaccination did not correlate with lung function, radiological findings such as bronchial wall thickening or exacerbation frequency. <h3>Conclusion</h3> Specific antibody deficiency is commonly seen in patients with asthma and fungal disease. Vaccination can provide protection and should be considered in this patient group. We need further analysis with a larger cohort of patients to study the association between antibody deficiency, lung function, radiological changes and disease progression.
Abstract B22: Novel dual regulation of epithelial-mesenchymal transition and anoikis resistance prevents metastases of triple negative breast cancer
Authors: Koichi Ito, Sun Hee Park, Anupma Nayak, Hanna Y. Irie
Journal: Clinical Cancer Research (2017)

Abstract Triple negative breast cancers (TNBC) are associated with a higher rate of metastatic recurrence and poorer prognosis due to intrinsic biological aggressiveness and lack of targeted therapies. Novel strategies to prevent metastasis are needed to improve outcomes for patients diagnosed with TNBC. Epithelial-mesenchymal transition (EMT) and anoikis resistance are processes recognized as contributing to treatment resistance and enhanced metastatic potential. In a functional genomic screen, we identified several candidates as novel dual regulators of EMT and anoikis sensitivity of triple negative breast cancer cells, that can be pharmacologically targeted to prevent metastases. One highly validated candidate, PTK6/Brk, specifically enhances anoikis resistance and metastatic potential of triple negative breast cancer cells via E-cadherin regulation. Overexpression of PTK6 in non-transformed immortalized breast epithelial cells is sufficient to promote an EMT, whereas PTK6 inhibition (either PTK6 shRNA or kinase inhibitor treatment) enhances E-cadherin expression and suppresses migration and lung colonization of TNBC cells. PTK6-dependent E-cadherin regulation and anoikis resistance is specifically dependent on levels of SNAIL, a transcriptional repressor. SNAIL down-regulation by PTK6 inhibition is directly responsible for modulation of anoikis sensitivity, which is in turn causally linked to lung colonization potential. PTK6 inhibition promotes the degradation of SNAIL via a novel mechanism independent of GSK3β and Fbox proteins known to regulate Snail ubiquitination. Using an siRNA screening approach, we identified novel E3 ligase candidates responsible for SNAIL ubiquitination and degradation downstream of PTK6 inhibition. PTK6 is a representative novel regulator of EMT and anoikis resistance that can be targeted to prevent metastases of patient triple negative tumors. Citation Format: Koichi Ito, Sun Hee Park, Anupma Nayak, Hanna Y. Irie. Novel dual regulation of epithelial-mesenchymal transition and anoikis resistance prevents metastases of triple negative breast cancer. [abstract]. In: Proceedings of the AACR Precision Medicine Series: Targeting the Vulnerabilities of Cancer; May 16-19, 2016; Miami, FL. Philadelphia (PA): AACR; Clin Cancer Res 2017;23(1_Suppl):Abstract nr B22.
Outcomes of Pharmacokinetically (PK) Directed Busulfan in Combination with Thiotepa &amp; Cyclophosphamide (TBC) Conditioning with HDT-ASCT in Patients with Primary &amp; Secondary CNS Lymphoma
Authors: Valkal Bhatt, Michael Scordo, Meier Hsu, Antonio M. Omuro, Lisa DeAngelis, Andrew Lin, Matthew J. Matasar, Parastoo B. Dahi, Craig H. Moskowitz, Sergio A. Giralt, Craig S. Sauter
Journal: Blood (2015)
PDGFR-Mediated Cytomegalovirus Infection of Megakaryocytes Induces Thrombocytopenia Via Demethylation of AML1 and IEX-1 in the TPO/c-Mpl Signaling Pathway Following Allo-HSCT
Authors: Xiao-Hui Zhang, Feng Fei-er, Qian-ming Wang, Xiao-lu Zhu, Lan-ping Xu, Xiao Jun Huang
Journal: Blood (2014)
Correction of Sickle Cell Anemia with γ-Globin Gene Delivered by Lentivirus Vector in the Setting of Myeloablative or Reduced Intensity Conditioning, and Establishing Critical Determinants for Successful Gene Therapy for Sickle Cell Disease.
Authors: Ajay Perumbeti, Tomoyasu Higashimoto, Fabrizia Urbinati, Kristy Lauderback, Anastacia Loberg, Gabriel Estevez-Pagani, Herbert Meiselman, Robert Franco, David Witte, Clinton H. Joiner, Punam Malik
Journal: Blood (2008)
P1.05-077 Outcome of N2 Disease in NSCLC - A Single Institution Experience
Authors: Lela Bitar, Fran Seiwerth, Ivona Markelić, Marta Koršić, Sanja Pleština, Branka Čučević, Suzana Kukulj, Mihovil Roglić, Marko Jakopović, Miroslav Samaržija
Journal: Journal of Thoracic Oncology (2017)
Clot Structure: A Potent Mortality Risk Factor in Patients on Hemodialysis
Authors: Katharina Schuett, Anna Savvaidis, Sebastian Maxeiner, Katharina Lysaja, Vera Jankowski, Stephan H. Schirmer, Nada Dimkovic, Peter Boor, Nadine Kaesler, Friedo W. Dekker, Jürgen Floege, Nikolaus Marx, Georg Schlieper
Journal: Journal of the American Society of Nephrology (2017)

Patients with CKD on hemodialysis exhibit increased cardiovascular risk. Fibrin clot structure and clot lysis are crucially involved in development of cardiovascular events, but little is known about the influence of clot density on outcome in patients on hemodialysis. We determined fibrin clot structure parameters and effect on mortality in a prospective cohort of 171 patients on chronic hemodialysis (mean±SD age =59±11 years old; 54% men) using a validated turbidimetric assay. Kaplan–Meier analysis revealed that patients on hemodialysis with a denser clot structure had increased all–cause and cardiovascular mortality risks (log rank P =0.004 and P =0.003, respectively). Multivariate Cox regression models (adjusted for age, diabetes, sex, and duration of dialysis or fibrinogen, C-reactive protein, and complement C3) confirmed that denser clots are independently related to mortality risk. We also purified fibrinogen from healthy controls and patients on hemodialysis using the calcium–dependent IF-1 mAb against fibrinogen for additional investigation using mass spectrometric analysis and electron microscopy. Whereas purified fibrinogen from healthy controls displayed no post-translational modifications, fibrinogen from patients on hemodialysis was glycosylated and guanidinylated. Clots made of purified fibrinogen from patients on hemodialysis exhibited significantly thinner fibers compared with clots from fibrinogen of control individuals (mean±SD =63±2 and 77±2 nm, respectively; P &lt;0.001). In vitro guanidinylation of fibrinogen from healthy subjects increased the formation of thinner fibers, suggesting that difference in fiber thickness might be at least partially due to post-translational modifications. Thus, in patients on hemodialysis, a denser clot structure may be a potent independent risk factor for mortality.
P1.03-023 Ground-Glass Opacity (GGO) with Semi-Consolidation: Clinicopathological and Radiological Correlations Compared to Pure-GGOs of the Lung
Authors: Jun Suzuki, Aritoshi Hattori, Takeshi Matsunaga, Kazuya Takamochi, Shiaki Oh, Kenji Suzuki
Journal: Journal of Thoracic Oncology (2017)
Bortezomib-Based Induction Therapy Followed by Autologous Stem Cell Transplantation and Maintenance Therapy with Bortezomib Improves Outcome In Myeloma Patients with Gain 1q21 and t(4;14) - a Subgroup Analysis of the HOVON-65/GMMG-HD4 Trial
Authors: Hartmut Goldschmidt, Kai Neben, Uta Bertsch, Thomas Hielscher, Bronno van der Holt, Dirk Hose, Laila el Jarari, Hans Salwender, Igor Wolfgang Blau, Michael Pfreundschuh, Ulrich Duehrsen, Katja Weisel, Hans Martin, Walter Lindemann, Christian Teschendorf, Mathias Haenel, Christof Scheid, Helgi van de Velde, Hans Guenter Derigs, Martin Hoffmann, Norma Peter, Martin Kaufmann, Ingo Schmidt-Wolf, Anna Jauch, Henk M Lokhorst, Pieter Sonneveld
Journal: Blood (2010)
PUB119 Lanreotide in Patients with Lung Neuroendocrine Tumors: The Randomized Double-Blind Placebo-Controlled International Phase 3 SPINET Study
Authors: Diane Reidy-Lagunes, Michael Kulke, Edward Wolin, Simron Singh, Diego Ferone, Dieter Hoersch, Beloo Mirakhur, Philipp Hoffmanns, Aude Houchard, Martyn Caplin, Eric Baudin
Journal: Journal of Thoracic Oncology (2017)
MA17.05 Evolutionary Trajectories of Molecular Progression in Different Subtypes of Primary Lung Adenocarcinomas
Authors: Hao-Ran Zhai, Shiyong Li, Bing Liao, Lixu Yan, Jian Su, Zhi-Yong Chen, Shuang Gao, Song Dong, Ben-Yuan Jiang, Xue-Ning Yang, Qing Zhou, Jin-Ji Yang, Xu-Chao Zhang, Mao Mao, Wen-Zhao Zhong, Yi Long Wu
Journal: Journal of Thoracic Oncology (2017)
A Recombinant Antibody to Siglec-8 Shows Selective ADCC Activity Against Mast Cells from Systemic Mastocytosis Patients
Authors: Rustom Falahati, Jessica Bright, Alejandro Dorenbaum, Christopher Bebbington, Nenad Tomasevic, Diane Lidke, Tracy I. George, Jason Gotlib
Journal: Blood (2015)
Phase I Study of BT062 Given as Repeated Single Dose Once Every 3 Weeks in Patients with Relapsed or Relapsed/Refractory Multiple Myeloma.
Authors: Asher A. Chanan-Khan, Sundar Jagannath, Leonard T. Heffner, David Avigan, Kelvin P. Lee, Robert J Lutz, Thomas Haeder, Markus Ruehle, Christoph Uherek, Andrea Barbara Wartenberg-Demand, Nikhil Munshi, Kenneth C. Anderson
Journal: Blood (2009)