Decreasing Prevalence of Chronic Kidney Disease in the United States: A Cause for Optimism
Authors: Linda F. Fried, Paul M. Palevsky
Journal: Annals of Internal Medicine (2016)

Editorials4 October 2016Decreasing Prevalence of Chronic Kidney Disease in the United States: A Cause for OptimismLinda F. Fried, MD, MPH and Paul M. Palevsky, MDLinda F. Fried, MD, MPHFrom VA Pittsburgh Healthcare System and University of Pittsburgh, Pittsburgh, Pennsylvania.Search for more papers by this author and Paul M. Palevsky, MDFrom VA Pittsburgh Healthcare System and University of Pittsburgh, Pittsburgh, Pennsylvania.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/M16-1649 SectionsSupplemental MaterialAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail This article has been corrected. The original version (PDF) is appended to this article as a Supplement.Chronic kidney disease (CKD) is a significant but often underappreciated public health concern. Its major causes are diabetes and hypertension, both potentially modifiable conditions. Although much of the focus has been on the most advanced manifestation of CKD—end-stage renal disease (ESRD), which affects approximately 700 000 persons in the United States—the full spectrum of CKD affects more than 30 million persons (1). The recognition that ESRD is only the “tip of the iceberg,” combined with an increasing recognition that even milder stages of CKD ...References1. United States Renal Data System. 2015 USRDS Annual Data Report: Epidemiology of Kidney Disease in the United States. Bethesda, MD: National Institutes of Health; 2015. Google Scholar2. National Center for Health Statistics. Healthy People 2010 Final Review. Hyattsville, MD: National Center for Health Statistics; 2012. Google Scholar3. Coresh J, Selvin E, Stevens LA, Manzi J, Kusek JW, Eggers P, et al. Prevalence of chronic kidney disease in the United States. JAMA. 2007;298:2038-47. [PMID: 17986697] CrossrefMedlineGoogle Scholar4. Murphy D, McCulloch CE, Lin F, Banerjee T, Bragg-Gresham JL, Eberhardt MS, et al; Centers for Disease Control and Prevention Chronic Kidney Disease Surveillance Consortium. Trends in prevalence of chronic kidney disease in the United States. Ann Intern Med. 2016;165:473-81. doi:10.7326/M16-0273 LinkGoogle Scholar5. Effects of Intensive Blood Pressure Lowering on the Progression of Chronic Kidney Disease. Accessed at www.healthypeople.gov/2020/topics-objectives/topic/chronic-kidney-disease on 13 July 2016. Google Scholar6. Glassock RJ, Winearls C. Diagnosing chronic kidney disease. Curr Opin Nephrol Hypertens. 2010;19:123-8. [PMID: 20040867] doi:10.1097/MNH.0b013e328335f951 CrossrefMedlineGoogle Scholar7. Myers GL, Miller WG, Coresh J, Fleming J, Greenberg N, Greene T, et al; National Kidney Disease Education Program Laboratory Working Group. Recommendations for improving serum creatinine measurement: a report from the Laboratory Working Group of the National Kidney Disease Education Program. Clin Chem. 2006;52:5-18. [PMID: 16332993] CrossrefMedlineGoogle Scholar8. Boutten A, Bargnoux AS, Carlier MC, Delanaye P, Rozet E, Delatour V, et al; Société Française de Biologie Clinique. Enzymatic but not compensated Jaffe methods reach the desirable specifications of NKDEP at normal levels of creatinine. Results of the French multicentric evaluation. Clin Chim Acta. 2013;419:132-5. [PMID: 23415696] doi:10.1016/j.cca.2013.01.021 CrossrefMedlineGoogle Scholar9. Schmidt RL, Straseski JA, Raphael KL, Adams AH, Lehman CM. A risk assessment of the Jaffe vs enzymatic method for creatinine measurement in an outpatient population. PLoS One. 2015;10:e0143205. [PMID: 26599086] doi:10.1371/journal.pone.0143205 CrossrefMedlineGoogle Scholar10. Plantinga LC, Boulware LE, Coresh J, Stevens LA, Miller ER, Saran R, et al. Patient awareness of chronic kidney disease: trends and predictors. Arch Intern Med. 2008;168:2268-75. [PMID: 19001205] doi:10.1001/archinte.168.20.2268 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From VA Pittsburgh Healthcare System and University of Pittsburgh, Pittsburgh, Pennsylvania.Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M16-1649.Corresponding Author: Paul M. Palevsky, MD, VA Pittsburgh Healthcare System, Renal Section (111F-U), University Drive, Pittsburgh, PA 15240; e-mail, [email protected]edu.Current Author Addresses: Drs. Fried and Palevsky: VA Pittsburgh Healthcare System, Renal Section (111F-U), University Drive, Pittsburgh, PA 15240.This article was published at www.annals.org on 2 August 2016. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoTrends in Prevalence of Chronic Kidney Disease in the United States Daniel Murphy , Charles E. McCulloch , Feng Lin , Tanushree Banerjee , Jennifer L. Bragg-Gresham , Mark S. Eberhardt , Hal Morgenstern , Meda E. Pavkov , Rajiv Saran , Neil R. Powe , Chi-yuan Hsu , and Correction: Decreasing Prevalence of Chronic Kidney Disease in the United States Metrics Cited byDevelopment and implementation of a Telenephrology dashboard for active surveillance of kidney disease: a quality improvement projectCorrection: Decreasing Prevalence of Chronic Kidney Disease in the United StatesMatrix Metalloproteinases-7 and Kidney Fibrosis 4 October 2016Volume 165, Issue 7Page: 521-522KeywordsChronic kidney diseaseCreatinineElderlyEstimated glomerular filtration rateKidneysPopulation statisticsPrevention, policy, and public healthRenal failureRenal systemResearch laboratories ePublished: 2 August 2016 Issue Published: 4 October 2016 PDF downloadLoading ...