Update in Hospital Medicine: Evidence Published in 2015
Authors: Jordan Messler, John B. Bulger
Journal: Annals of Internal Medicine (2016)

Updates3 May 2016Update in Hospital Medicine: Evidence Published in 2015Jordan Messler, MD and John B. Bulger, DO, MBAJordan Messler, MDFrom Morton Plant Hospitalists, Clearwater, Florida, and Geisinger Health System, Danville, Pennsylvania.Search for more papers by this author and John B. Bulger, DO, MBAFrom Morton Plant Hospitalists, Clearwater, Florida, and Geisinger Health System, Danville, Pennsylvania.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/M16-0224 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail We discuss 10 practice-changing studies that were published in 2015. Two studies examined the effect of hospitalization on patient cognition and delirium. Two more studies should change the treatment of community-acquired pneumonia; one looked at the use of steroids, and another the choice of initial antibiotic. Two additional studies were about critical care: One examined the use of high-flow oxygen in patients with acute hypoxemic respiratory failure, and the other examined the effectiveness of early goal-directed therapy in septic shock. Finally, we review one of several studies published in 2015 that examined the effectiveness of bridging therapy for patients receiving ...References1. Wilson RS, Hebert LE, Scherr PA, Dong X, Leurgens SE, Evans DA. Cognitive decline after hospitalization in a community population of older persons. Neurology. 2012;78:950-6. [PMID: 22442434] doi:10.1212/WNL.0b013e31824d5894 CrossrefMedlineGoogle Scholar2. Inouye SK, Westendorp RG, Saczynski JS. Delirium in elderly people. Lancet. 2014;383:911-22. [PMID: 23992774] doi:10.1016/S0140-6736(13)60688-1 CrossrefMedlineGoogle Scholar3. Inouye SK, Bogardus ST, Charpentier PA, Leo-Summers L, Acampora D, Holford TR, et al. A multicomponent intervention to prevent delirium in hospitalized older patients. 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[PMID: 26010033] doi:10.1001/jamainternmed.2015.1843 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Morton Plant Hospitalists, Clearwater, Florida, and Geisinger Health System, Danville, Pennsylvania.Disclosures: Dr. Messler reports personal fees from the Society of Hospital Medicine outside the submitted work. Dr. Bulger reports personal fees from the American Board of Internal Medicine Foundation outside the submitted work and membership in the National Quality Forum All-Cause Admissions and Readmissions Steering Committee for the All-Cause Admissions and Readmissions Endorsement Maintenance project. Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M16-0224.Editors' Disclosures: Christine Laine, MD, MPH, Editor in Chief, reports that she has no financial relationships or interests to disclose. Darren B. Taichman, MD, PhD, Executive Deputy Editor, reports that he has no financial relationships or interests to disclose. Cynthia D. Mulrow, MD, MSc, Senior Deputy Editor, reports that she has no relationships or interests to disclose. Deborah Cotton, MD, MPH, Deputy Editor, reports that she has no financial relationships or interest to disclose. Jaya K. Rao, MD, MHS, Deputy Editor, reports that she has stock holdings/options in Eli Lilly and Pfizer. Sankey V. Williams, MD, Deputy Editor, reports that he has no financial relationships or interests to disclose. Catharine B. Stack, PhD, MS, Deputy Editor for Statistics, reports that she has stock holdings in Pfizer.Corresponding Author: Jordan Messler, MD, Morton Plant Hospitalists, 300 Pinellas Street, #47, Clearwater, FL 33756; e-mail, jordan.[email protected]org.Current Author Addresses: Dr. Messler: Morton Plant Hospitalists, 300 Pinellas Street, #47, Clearwater, FL 33756.Dr. Bulger: Geisinger Health System, 100 North Academy Avenue, Danville, PA 17822.Author Contributions: Conception and design: J. Messler, J.B. Bulger.Analysis and interpretation of the data: J. Messler, J.B. Bulger.Drafting of the article: J. Messler, J.B. Bulger.Critical revision of the article for important intellectual content: J. Messler, J.B. Bulger.Final approval of the article: J. Messler, J.B. Bulger.Collection and assembly of data: J. Messler, J.B. Bulger. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 3 May 2016Volume 164, Issue 9Page: W37-W41KeywordsAntibioticsDeliriumHospitalizationsIntensive care unitsMortalityOxygenPneumoniaRespiratory failureShockSteroids ePublished: 3 May 2016 Issue Published: 3 May 2016 Copyright & PermissionsCopyright © 2016 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...