tbuckley/cabot-search huggingface dataset:
Dysregulation of Rab37-Mediated Cross-talk between Cancer Cells and Endothelial Cells via Thrombospondin-1 Promotes Tumor Neovasculature and Metastasis
Authors: Hong-Tai Tzeng, Chung-Han Tsai, Yi-Ting Yen, Hung-Chi Cheng, Yi-Chieh Chen, Shih-Wen Pu, Yu-Shiuan Wang, Yan-Shen Shan, Yau-Lin Tseng, Wu-Chou Su, Wu-Wei Lai, Li-Wha Wu, Yi-Ching Wang
Journal: Clinical Cancer Research (2016)

Abstract Purpose: Accumulating evidence indicates that factors secreted by cancer epithelial cells shape the tumor microenvironment to promote cancer invasion and metastasis. Recent studies also shed light on alterations of Rab small GTPase–mediated exocytosis in tumorigenesis. However, the mechanisms for Rab-mediated exocytosis in tumor microenvironment remain elusive. We aimed to investigate the interplay between Rab37-mediated exocytosis and tumor microenvironment, focusing on endothelial cell motility and angiogenesis. Experimental Design: We performed fluorescence IHC for Rab37, thrombospondin-1 (TSP1, an antiangiogenesis factor), and angiogenesis marker CD31 in 183 surgically resected esophageal squamous cell carcinoma (ESCC) patient samples. Cell migration, invasion, angiogenesis, and tumor metastasis were measured. Results: ESCC patients with low expression of Rab37 or TSP1 significantly correlated with high CD31 expression and were associated with worse progression-free survival. The multivariate Cox regression analysis showed that concordant low expression of both Rab37 and TSP1 was an independent prognostic factor of ESCC patients. Rab37-mediated exocytosis of TSP1 led to the inhibition of neovasculature in vitro and in vivo. Secreted TSP1 from cancer cells with Rab37 exocytic function inhibited the p-FAK/p-paxillin/p-ERK migration signaling in both cancer epithelial cells and their surrounding endothelial cells. Dysfunction of Rab37 or loss of TSP1 abrogated the suppressive effects on angiogenesis and metastasis. Conclusions: Our findings suggest that Rab37-mediated TSP1 secretion in cancer cells suppresses metastasis and angiogenesis via a cross-talk with endothelial cells and reveal a novel component of the vesicular exocytic machinery in tumor microenvironment and tumor progression. Dysregulation of Rab37/TSP1 axis has clinical implications for prognosis prediction. Clin Cancer Res; 23(9); 2335–45. ©2016 AACR.
Non-T-Cell-Depleted HLA-Haploidentical Hematopoietic Stem Cell Transplantation for Children with Hematological Malignancies: Single-Center Pilot Study
Authors: Kazuhiro Mochizuki, Atsushi Kikuta, Masaki Ito, Hideki Sano, Shogo Kobayashi, Hitoshi Ohto, Mitsuaki Hosoya
Journal: Blood (2008)
Evaluation of the Feasibility of Screening Patients for Early Signs of Lung Carcinoma in Web Search Logs
Authors: Ryen W. White, Eric Horvitz
Journal: JAMA Oncology (2016)

A statistical model that predicts the appearance of strong evidence of a lung carcinoma diagnosis via analysis of large-scale anonymized logs of web search queries from millions of people across the United States.To evaluate the feasibility of screening patients at risk of lung carcinoma via analysis of signals from online search activity.We identified people who issue special queries that provide strong evidence of a recent diagnosis of lung carcinoma. We then considered patterns of symptoms expressed as searches about concerning symptoms over several months prior to the appearance of the landmark web queries. We built statistical classifiers that predict the future appearance of landmark queries based on the search log signals. This was a retrospective log analysis of the online activity of millions of web searchers seeking health-related information online. Of web searchers who queried for symptoms related to lung carcinoma, some (n = 5443 of 4 813 985) later issued queries that provide strong evidence of recent clinical diagnosis of lung carcinoma and are regarded as positive cases in our analysis. Additional evidence on the reliability of these queries as representing clinical diagnoses is based on the significant increase in follow-on searches for treatments and medications for these searchers and on the correlation between lung carcinoma incidence rates and our log-based statistics. The remaining symptom searchers (n = 4 808 542) are regarded as negative cases.Performance of the statistical model for early detection from online search behavior, for different lead times, different sets of signals, and different cohorts of searchers stratified by potential risk.The statistical classifier predicting the future appearance of landmark web queries based on search log signals identified searchers who later input queries consistent with a lung carcinoma diagnosis, with a true-positive rate ranging from 3% to 57% for false-positive rates ranging from 0.00001 to 0.001, respectively. The methods can be used to identify people at highest risk up to a year in advance of the inferred diagnosis time. The 5 factors associated with the highest relative risk (RR) were evidence of family history (RR = 7.548; 95% CI, 3.937-14.470), age (RR = 3.558; 95% CI, 3.357-3.772), radon (RR = 2.529; 95% CI, 1.137-5.624), primary location (RR = 2.463; 95% CI, 1.364-4.446), and occupation (RR = 1.969; 95% CI, 1.143-3.391). Evidence of smoking (RR = 1.646; 95% CI, 1.032-2.260) was important but not top-ranked, which was due to the difficulty of identifying smoking history from search terms.Pattern recognition based on data drawn from large-scale web search queries holds opportunity for identifying risk factors and frames new directions with early detection of lung carcinoma.
Long-Term Outcomes after Myeloablative Allogeneic Hematopoietic Cell Transplantation for Adult Acute Lymphoblastic Leukemia
Authors: Moaath Mustafa Ali, Donna M Abounader, Lisa A. Rybicki, Jamie Starn, Christina Ferraro, Victoria Winslow, Betty K. Hamilton, Aaron T. Gerds, Hien Liu, Robert M. Dean, Rabi Hanna, Matt Kalaycio, Brian J. Bolwell, Anjali Advani, Navneet S. Majhail, Ronald Sobecks
Journal: Blood (2015)
Impact of IgVH Gene Mutational Status and VH Family Usage on Chromosomal Aberrations Detected by High-Resolution Array-CGH in B-CLL.
Authors: Jose F Leis, Esteban Braggio, Scott Van Wier, Jonathan J Keats, Diane F. Jelinek, Daniel van Dyke, Clive S. Zent, Tait D. Shanafelt, Timothy G Call, Neil E. Kay, Rafael Fonseca
Journal: Blood (2009)
Understanding rare and common diseases in the context of human evolution
Authors: Lluis Quintana-Murci
Journal: Genome biology (2016)

The wealth of available genetic information is allowing the reconstruction of human demographic and adaptive history. Demography and purifying selection affect the purge of rare, deleterious mutations from the human population, whereas positive and balancing selection can increase the frequency of advantageous variants, improving survival and reproduction in specific environmental conditions. In this review, I discuss how theoretical and empirical population genetics studies, using both modern and ancient DNA data, are a powerful tool for obtaining new insight into the genetic basis of severe disorders and complex disease phenotypes, rare and common, focusing particularly on infectious disease risk.
APcK 110, a novel Inhibitor of Kit, Extends Survival of NOD-SCID Mice in An AML Xenograft Model.
Authors: Stefan Faderl, Carlos Bueso-Ramos, Zhiming Liu, Ashutosh Pal, William Bornmann, David Harris, Inbal Hazan-Halevy, Hagop M. Kantarjian, Zeev Estrov
Journal: Blood (2009)
Eosinophilia, Positive ANA, and Hypergammaglobulinemia at Presentation of Extensive Chronic GVHD in Children: A Children’s Oncology Group Study.
Authors: David A. Jacobsohn, Kirk R. Schultz, Frederick Goldman, Donna A. Wall, Mark Krailo, Zhengjia Chen, Jeffrey M. Lipton, Jean E. Sanders, Andrew L. Gilman
Journal: Blood (2005)
Astatine-211 Conjugated To Anti-CD20 Monoclonal Antibody Eliminates B-Cell Lymphoma In a Mouse Model
Authors: Damian J. Green, Mazyar Shadman, Shani L. Frayo, Jon C. Jones, Mark D. Hylarides, Aimee L. Kenoyer, D. Scott Wilbur, Donald K. Hamlin, Yukang Lin, Ajay K. Gopal, Sofia H.L. Frost, Johnnie J. Orozco, John M. Pagel, Oliver W. Press
Journal: Blood (2013)
Effect of Genetic Polymorphisms Related to Folate and Homocysteine Metabolism In the Etiology of Recurrent Miscarriages
Authors: Elvira Maria Guerra-Shinohara, Kelma Cordeiro da Silva Giusti, Nathalia Sierra Monteiro, Robson José Lazaro, Fernanda Midori Seino, Carolina Tosin Bueno, Mário Henrique Burlacchini Carvalho, Antônio Amorim Filho, Carlos Chiattone, Marcelo Zugaib
Journal: Blood (2010)
A biomaterial-assisted mesenchymal stromal cell therapy alleviates colonic radiation-induced damage
Authors: Lara Moussa, Girish Pattappa, Bastien Doix, Sarra-Louiza Benselama, Christelle Demarquay, Marc Benderitter, Alexandra Sémont, Radia Tamarat, Jérôme Guicheux, Pierre Weiss, Gildas Réthoré, Noëlle Mathieu
Journal: Biomaterials (2016)

Healthy tissues surrounding abdomino-pelvic tumours can be impaired by radiotherapy, leading to chronic gastrointestinal complications with substantial mortality. Adipose-derived Mesenchymal Stromal Cells (Ad-MSCs) represent a promising strategy to reduce intestinal lesions. However, systemic administration of Ad-MSCs results in low cell engraftment within the injured tissue. Biomaterials, able to encapsulate and withstand Ad-MSCs, can overcome these limitations. A silanized hydroxypropylmethyl cellulose (Si-HPMC) hydrogel has been designed and characterized for injectable cell delivery using the operative catheter of a colonoscope. We demonstrated that hydrogel loaded-Ad-MSCs were viable, able to secrete trophic factors and responsive to the inflammatory environment. In a rat model of radiation-induced severe colonic damage, Ad-MSC + Si-HPMC improve colonic epithelial structure and hyperpermeability compared with Ad-MSCs injected intravenously or locally. This therapeutic benefit is associated with greater engraftment of Si-HPMC-embedded Ad-MSCs in the irradiated colonic mucosa. Moreover, macrophage infiltration near the injection site was less pronounced when Ad-MSCs were embedded in the hydrogel. Si-HPMC induces modulation of chemoattractant secretion by Ad-MSCs that could contribute to the decrease in macrophage infiltrate. Si-HPMC is suitable for cell delivery by colonoscopy and induces protection of Ad-MSCs in the tissue potentiating their therapeutic effect and could be proposed to patients suffering from colon diseases.
Effects of kinsenoside, a potential immunosuppressive drug for autoimmune hepatitis, on dendritic cells/CD8+T cells communication in mice
Authors: Ming Xiang, Tingting Liu, Wanyue Tan, Hongyu Ren, Hua Li, Junjun Liu, Hui Cao, Qi Cheng, Xiulan Liu, Hucheng Zhu, Yali Tuo, Jianping Wang, Yonghui Zhang
Journal: Hepatology (2016)

The central purpose of this study was to investigate therapeutic effects of the botanical derivative, kinsenoside (KD), in experimental autoimmune hepatitis (AIH). Treatment with KD substantially reduced hepatic histopathological damage, induced by lymphocyte infiltration and proinflammatory cytokines, in concanavalin A-induced T-cell-mediated hepatitis, and in dendritic cells (DCs) loaded with hepatocellular carcinoma cells (DC/Hepa1-6) induced murine AIH. Interactions between immune cells after KD treatment in AIH were detected by anti-CD8 antibody blocking, CD8+ T cell sorting, and vaccinated mice with KD-pretreated DCs in a DC/Hepa1-6 model. These results showed that KD inhibited the elevated expressions of CD86 and major histocompatibility complex II, densities of chemokine receptor C-C chemokine receptor type 7, and extensive migration to lymph nodes, and increased the programmed death ligand 1 level of DCs, followed by suppressing CD8+ T cells, characterized as low differentiation and cytotoxicity, and eliciting cytokines balance. Furthermore, biochemical analysis, two-dimensional fingerprint screen and three-dimensional molecular docking results showed that KD bound to the vascular endothelial growth factor receptor 2 (VEGFR2) kinase domain, which inhibited the metabolism-related phosphatidylinositol 3 kinase/protein kinase B (PI3K-AKT) pathway in DCs and DC-modulated CD8+ T cells to lower the mitochondrial membrane potential and glucose/lipid utilization ratio in both cells. KD reversed activation of the PI3K-AKT pathway by 740 Y-P (PI3K agonist), thereby impeding the translocation and dimerization of signal transducer and activators of transcription (STAT) 3 and synergistically blocking the inflammation-related Janus kinase (JAK) 2/STAT3 pathway in DCs and DC-modulated T cells.KD treatment elicits immunosuppression against autoimmune liver injury by targeting VEGFR2, followed by diminishing the cross-talk of metabolism-related PI3K-AKT and inflammation-related JAK2-STAT3 pathways, and thereby disrupts DC-induced cross-priming of CD8+ T cell responses. (Hepatology 2016;64:2135-2150).
Xeroderma Pigmentosum Group B Binding Contributes to p210 BCR/ABL Mediated Transformation in CML.
Authors: Nicole L Pannucci, Sutapa Sahay, Emily K Thomas, Ru Chen, Nicholas J Megjugorac, Homer C Adams, Pedro L Rodriguez, Ethan R Fitzpatrick, David A. Williams, Ian P Whitehead
Journal: Blood (2008)
CALM-AF10 Positive T-ALLs Show a Pattern of Expression Similar to MLL-Translocated Acute Leukemias.
Authors: Eric Delabesse, Wim A. Dik, Wajih Brahim, Charlene Braun, Vahid Asnafi, Jacques J.M. Van Dongen, Anton W. Langerak, Elizabeth A. Macintyre
Journal: Blood (2004)
Hematopoietic Stem-Cell Transplantation from Unrelated Donors in Elderly Patients (&amp;gt; 55 Years): Older Age Is No Longer a Contraindication When Using Reduced Intensity Conditioning.
Authors: Avichai Shimoni, Nicolaus Kröger, Tatjana Zabelina, Frances Ayuk, Izhar Hardan, Moshe Yeshurun, Noga Shem-Tov, Abraham Avigdor, Isacc Ben-Bassat, Axel Zander, Arnon Nagler
Journal: Blood (2004)
Hyperchidam Verona897 Regimen Is Effective in Treatment of Advanced Peripheral T Cell Lymphoma (PTCL): The GITIL Experience in 33 Cases.
Authors: Giuseppe Todeschini, Paolo Corradini, Sergio Cortelazzo, Alessandro Rambaldi, Andrea Gallamini, Fabio Benedetti, Andres Ferreri, Attilio Olivieri, Cristina Tecchio, Massimiliano Bonifacio, Niccolo Frungillo, Claudia Castellino, Andrea Rossi, Chandrakala Toldo, Roberto Crocchiolo, Immacolata Attolico, Giovanni Pizzolo
Journal: Blood (2007)
Can sarcopenia be used as a prognostic indicator in patients with metastatic penile cancer?
Authors: M. Christodoulidou, D. Gibson, S. Burden, N. Ramachandran, C. Attipa, A. Mitra, S. Lal, P. Malone, R. Nigam, T. Richards, A. Muneer
Journal: International Journal of Surgery (2016)
SP0091 Can Individual Patients Benefit from Registries?
Authors: S. Ernestam
Journal: Annals of the Rheumatic Diseases (2016)

SRQ, the Swedish Rheumatology Quality Care Register, has more than 60 000 registered patients with different inflammatory conditions, mainly arthritis diseases. Approximately 20 000 patients are on treatment with biologic drugs and a total of 35 000 patients have ever been treated with biological drugs. All rheumatology units in Sweden are part of the register. The variables registered are mainly patient reported outcomes such as global health on a visual analogue scale, pain on a visual analoge scale, fatigue, HAQ and number of swollen and tender joints registered by both patient and provider. The patient may register their data before the consultation at a secure web page or at a computer in the waiting room. During the consultation the results of the patient reported outcome measurements are visualised to both the patient and provider and a shared decision of treatment are agreed on together. A treatment plan may be made on both medications and life style factors. Patients may themselves take part of their individual results over time from home. During the session a short film about the way of working with SRQ will be shown. <h3>Disclosure of Interest</h3> None declared
Homoharringtonine-Based Induction Regimens for Patients with De Novo Acute Myeloid Leukemia: A Multicenter Randomized Controlled Phase 3 Trial
Authors: Jie Jin, Jianxiang Wang, Feifei Chen, Depei Wu, Jiong Hu, Jianfeng Zhou, Jianda Hu, Jianmin Wang, Jianyong Li, Xiaojun Huang, Jun Ma, Chunyan Ji, Xiaoping Xu, Kang Yu, Hanyun Ren, Yuhong Zhou, Yin Tong, Yingchang Mi, Xin Du, Baoan Chen, Zhu Chen, Sai-Juan Chen
Journal: Blood (2012)
Upfront Autologous Stem Cell Transplantation (SCT) Ameliorates the Prognostic Disadvantage of an Intermediate/High-Risk FLIPI Score in Patients with Advanced Follicular Lymphoma (FL): Evidence from Two Independent Data Sets.
Authors: Kornacker Martin, Simone Suessmilch, Hilde Gulla, Baerbel Seyfarth, Robert Schoch, Michael Kneba, Anthony D. Ho, Manfred Hensel, Norbert Schmitz, Peter Dreger
Journal: Blood (2005)
Integrative Analysis of NPM1 Mutation-Associated MicroRNA and Gene Expression Signatures Identifies Potential Leukemia-Relevant Genes in Acute Myeloid Leukemia.
Authors: Annika C Russ, Sonja C Lück, Sandrine Sander, Hartmut Döhner, Konstanze Döhner, Lars Bullinger
Journal: Blood (2009)
Особливості перебігу патології підшлункової залози в дітей
Authors: T.V. Sorokman, O.-M.V. Popelyuk
Journal: GASTROENTEROLOGY (2016)

Актуальність. Поширеність панкреатиту в дітей становить 5–25 %. Мета: визначити особливості патології підшлункової залози в дітей. Матеріал та методи. Дослідження проведено на базі гастроентерологічного відділення Чернівецької обласної клінічної дитячої лікарні впродовж 2013–2015 рр. Результати. Частота хронічного панкреатиту серед дітей Чернівецької області загалом становить 1,8 %. У 66 % дітей із хронічним гастродуоденітом і в 100 % дітей із виразковою хворобою цибулини дванадцятипалої кишки були виявлені ультразвукові зміни підшлункової залози. Ознаки хронічного панкреатиту відмічені в 1 дитини з целіакією і 4 дітей із лактазною недостатністю. У 17 дітей спостерігались ультразвукові ознаки фіброзу залози та зниження рівня еластази‑1 в калі, що можуть розглядатися як ознаки хронічного панкреатиту, у 9 дітей встановлено ультразвукові ознаки структурних змін підшлункової залози, але рівень еластази‑1 був нормальним (хворі з рецидивуючим панкреатитом), у 18 дітей не було ультразвукових змін структури залози та рівень еластази‑1 в калі не змінювався. Висновок. Хронічні панкреатити в дітей перебігають на фоні больового (нападоподібний біль із локалізацією в епігастрії або часта зміна локалізації болю), диспептичного (найчастіше проявляється нудотою та блюванням) і астеновегетативного синдромів та супроводжуються дисгармонійним фізичним розвитком. У всіх хворих із хронічним панкреатитом виявлено вогнищеві або лінійні фіброзні зміни паренхіми підшлункової залози, неспецифічні зміни в копрограмі та значне зниження рівня еластази‑1 у крові.
Circulating Memory T Cells Isolated from Hodgkin Lymphoma Patients Display Evidence of Exhaustion and Chronic Activation
Authors: Catherine S. Diefenbach, Bruce G. Raphael, Kenneth B. Hymes, Tibor Moskovits, David Kaminetzky, Peter Martin, Jia Ruan, Stephanie Lauro, Danielle Banks, Krysten Brown, Maryam Bonakdar, Cem Abidoglu, Lina Kozhaya, John P. Leonard, Derya Unutmaz
Journal: Blood (2014)
FRI0548 Responsiveness of A New MRI Scoring Method Based on The Canada-Denmark Definitions of Lesions in The Spine and The SPARCC MRI Spine Inflammation Index in Patients with Axial Spondyloarthritis: Table 1.
Authors: S. Krabbe, M. Østergaard, I.J. Sørensen, B. Jensen, J. Møller, L. Balding, O.R. Madsen, K.H. Asmussen, G.P. Eng, S.J. Pedersen
Journal: Annals of the Rheumatic Diseases (2016)

<h3>Background</h3> The Spondyloarthritis Research Consortium of Canada (SPARCC) Spine Inflammation Index is a well-established MRI scoring system for vertebral body inflammation.(1) It does not take the exact anatomical location of lesions into account. The Canada-Denmark (CanDen) MRI definitions were developed to allow detailed anatomical evaluation of inflammatory and structural lesions of the vertebral bodies as well as the posterior segments in patients with axial spondyloarthritis (axSpA).(2–3) <h3>Objectives</h3> The aim of this study was to assess the distribution of scores and the responsiveness of this new method, which combines the CanDen MRI definitions into a scoring system, as compared with the SPARCC Spine Inflammation Index in an axSpA randomized controlled trial. <h3>Methods</h3> For each disco-vertebral unit, inflammatory lesions of vertebral bodies (VB) in the anterior and posterior corners on central sagittal slices were scored as 1 (small) or 2 (large). Non-corner lesions were scored as 2 (small) or 4 (large). Antero-lateral and postero-lateral inflammatory corner lesions in lateral sagittal slices were scored as 1. Inflammatory lesions in the posterior segments (PS) were each scored as 1. Fat (4), erosion and new bone formation were scored in a comparable way (details not shown due to length restrictions). 49 patients with axSpA and indication for TNFα inhibitor were randomized to placebo or adalimumab 40 mg sc. eow for 6 weeks. MRI of the spine was scored according to CanDen definitions and SPARCC by an experienced reader blinded to the clinical data. Responsiveness was assessed by standardized response mean (SRM) and Guyatt9s responsiveness index (GRI). Values ≥0.8 represent a large degree of responsiveness. <h3>Results</h3> <h3>Conclusions</h3> A new anatomy-based scoring system for spine inflammatory and structural lesions was described, demonstrating similar responsiveness as the SPARCC method. Further studies are needed to investigate the additional value of assessing posterior segments. <h3>References</h3> Maksymowych et al. Arthritis Rheum 2005;53:502–9; Lambert et al. J Rheumatol 2009;36-S84:3–17; Østergaard et al. J Rheumatol 2009;36-S84:18–34; Pedersen et al. Arthritis Res Ther 2013;15:R216 <h3>Disclosure of Interest</h3> None declared
Roles and ranks: The importance of hierarchy for group functioning
Authors: Julian J Zlatev, Nir Halevy, Larissa Z Tiedens
Journal: Behavioral and Brain Sciences (2016)

Abstract Baumeister et al. propose that role differentiation is critical for group functioning. We propose that effective groups require rank differentiation in addition to role differentiation. We suggest that rank differentiation supports division of labor by incentivizing group members, satisfying fundamental human needs, and organizing and integrating the contributions of differentiated group members.
HSP70, the Key to Account for Erythroid Tropism of Diamond-Blackfan Anemia?
Authors: Marc Gastou, Sarah Rio, Mickael Dussiot, Narjesse Karboul, Thierry Leblanc, Margaux Sevin, Olivier Bluteau, Narla Mohandas, William Vainchenker, Carmen Garrido, Eric Solary, Olivier Hermine, Lydie Da Costa
Journal: Blood (2015)
In Vivo and Ex Vivo T-Cell Depleted (TCD) NonmyeloablativeHaploidentical Stem Cell Transplantation (NSCT) for Hematologic Malignancy (HM).
Authors: Thomas R. Spitzer, Steven L. McAfee, Dey R. Bimalangshu, Karen Ballen, Eyal Attar, Christine Colby, Fred Preffer, Susan Saidman, Juanita Shaffer, David H. Sachs, Megan Sykes
Journal: Blood (2005)
Febrile Neutropenia Following Autologous Stem Cell Transplantation in Patients with Lymphoma
Authors: Radovan Vrhovac, Zinaida Peric, Matko Kalac, Alen Ostojic, Visnja Kovacevic, Suzana Bukovski-Simonoski, Arjana Tambic-Andrasevic, Hrvoje Minigo, Branimir Jaksic
Journal: Blood (2008)
High Frequency of Tumor Suppressor Genes Promoter Hypermethylation in Peripheral Blood of Patients with Myelodysplastic Syndromes
Authors: Patrizia Bossolasco, Francesco Onida, Giorgia Saporiti, Carla Bozzi, Clara Ricci, Agostino Cortelezzi, Giorgio Lambertenghi Deliliers
Journal: Blood (2008)