tbuckley/cabot-search huggingface dataset:
PWE-037 Reliability of Arfi Shear Velocity Cut-Off for Diagnosis of Cirrhosis in Chronic Hepatitis C: A "Real World" Two Centre Simultaneous Biopsy-Controlled Study in The UK
Authors: N Gandy, P Lung, O Jaffer, P Tadrous, K Agarwal, M Heneghan, P Shorvon, P Sidhu, D Sherman
Journal: Gut (2016)

<h3>Introduction</h3> Non-invasive assessment of liver fibrosis with elastography is increasingly used as the sole diagnostic method to assess patients with HCV infection for suitability for new anti-viral therapies. Currently patients with cirrhosis form the majority of those funded for some oral treatments in England. A large proportion reside in London and the South East region. As shear velocity cut offs for Metavir F4 fibrosis with the ARFI technique (virtual touch quantification, VTq™) are based upon historical studies, which may have been subject to sources of bias, there is a need for disease specific, population adjusted data. We report the results of a biopsy controlled study from two centres, designed to investigate optimal ARFI cut-offs for determining cirrhosis in our population. <h3>Methods</h3> Our database of 96 patients with HCV infection obtained from two centres was interrogated. ARFI shear velocity (SV) estimation was performed with 10 right lobe measurements. Fibrosis stage was confirmed in 84 by right lobe liver biopsy within 2 hours of ARFI, and cirrhosis was confirmed by B-mode US imaging criteria in the remaining 12. Ultrasonic and histopathological data was collated retrospectively. Diagnostic performance of ARFI was determined by ROC analysis, using a) reference SV cut-off values for Metavir stage, and b) optimal SV thresholds for cirrhosis derived from our local data, including subgroup analysis. <h3>Results</h3> Three subgroups were analysed: 1) all 96 cases, including 20 patients with co-pathology (HBV, NAFLD, or ALD); 2) 76 cases with HCV only; 3) 84 cases who had simultaneous biopsy. Cirrhosis was present in 26, 20 and 14, respectively. Predictive accuracy for Metavir F4 using the reference threshold of 1.75 m/sec was 90%, 92% and 88% in groups 1, 2 and 3, respectively. Using new thresholds and ARFI mean SVs required a higher cutoff of 1.99 in group 1 compared with 1.64 in groups 2 and 3 to achieve accuracies of 87%–93%, whereas more consistent performance across all groups was achieved with median SVs at a cutoff of 1.89, achieving accuracies of 93%, 96% and 92%, respectively. <h3>Conclusion</h3> These “real world” data confirm the high predictive accuracy of ARFI for Metavir F4 cirrhosis in our local HCV cohort. Optimal performance was seen for median SV cutoff of 1.89 m/sec. However, adjustment of diagnostic thresholds may be necessary when making treatment decisions for less selected populations and in those patients with co-existent pathology. <h3>Disclosure of Interest</h3> None Declared
Case 6-1982
Authors: Richard C. Cabot, Robert E. Scully, Eugene J. Mark, Betty U. McNeely, Gerald S. Foster, James J. Galdabini
Journal: New England Journal of Medicine (1982)

Presentation of CaseA 55-year-old man was admitted to the hospital because of jaundice.He was well until 10 months earlier, when he noticed the onset of malaise. Eight months before admission he observed that his eyes were yellow. A physician made a diagnosis of hepatitis, and the patient discontinued his moderate intake of alcohol but did not improve. Six months before entry the malaise worsened. Two months before admission he entered another hospital, where an ultrasound study of the liver showed that the intrahepatic bile ducts were dilated and the wall of the gallbladder appeared thickened (Fig. 1); no . . .
FRI0290 Identification of at Risk Patients for Cardiac MRI Determined Sub-Clinical SSC-Cardiomyopathy (CM): Table 1.
Authors: L.-A. Bissell, B. Erhayiem, E. Hensor, G. Fent, J.P. Greenwood, S. Plein, J. Andrews, M.H. Buch
Journal: Annals of the Rheumatic Diseases (2016)

<h3>Background</h3> SSc-CM carries a poor prognosis once clinically evident. No clear management algorithm to guide screening &amp; investigation for SSc-CM exists. <h3>Objectives</h3> To describe cardiac MR (CMR) abnormalities in SSc pts free of CM/CVD &amp; their association with disease (dis.) phenotype to identify the "at risk" pt. <h3>Methods</h3> We compared 35 pts with ACR/EULAR criteria SSc &amp; no diabetes/clinical CVD who received SSc/cardiovascular (CV) profile &amp; pulse wave velocity (PWV) assessment &amp; 3T delayed enhancement-CMR reported by CMR-cardiologists to 30 healthy controls (HC). Univariate analysis variables (var.): CV traditional risk factors (TRF), waist/hip ratio (WHR), dis. duration, prev. digital ulceration (DU), known ILD, palpitations hx, dis. subtype, ACA, Scl70, MRSS, NFC, prev. use of cyclophosphamide, SHAQ, FVC, PASP &amp; PWV. <h3>Results</h3> Mean (SD) age (yrs) SSc pts 55 (13), 74% female; HC 50 (15), 63% female. Median (IQR) yrs from 1st non-RP symptom 9.5 (2.3, 19.6); 43% dcSSc, 31% ACA+ve, 34% Scl70+ve, 43% known ILD, 37% DU, 0% pulmonary hypertension, 29% prev. use of cyclophosphamide. CMR markers of fibrosis were increased in SSc: ECV (31% SSc vs 25% HC, p&lt;0.001 after adj. for age/sex/TRFs); late gadolinium enhancement (LGE) in 9 SSc vs 1 HC. In SSc, diastolic dysfunction was evident (reduced torsion p0.038), there was a trend for reduced LV mass &amp; RVEF was unexpectedly increased (p=0.028) vs HC. Higher ECV in SSc was associated (ass.) with DU (r0.397 p0.22), decreasing WHR (r-0.510 p0.004) &amp; decreasing TC/HDL (r-0.376 p0.037); none significantly ass. in multi-variable analysis with age/sex. LGE was significantly ass. with ILD (78% vs 33%, p0.047), absence of ACA (0% vs 42%, p0.032), reduced sysBP (mean diff. (95%CI) -14 (27, -1)mmHg p0.034) &amp; lower BMI (mean diff. (95%CI) -4.13 (-8.24, -0.02), p0.049). Other SSc LGE observations: male gender (56% vs 17% LGE-ve), 56% (vs 38% LGE-ve) dcSSc, 56% (vs 29%) Scl70+ve &amp; shorter dis. duration (median (IQR) 7.4 (1.2, 15.8) vs 10.9 (2.5, 19.7) yrs). <h3>Conclusions</h3> This study reports CMR detected sub-clinical SSc-CM with detailed SSc phenotype, associating with poor prognostic factors. These data indicate an at risk group for further evaluation that would justify more intensive monitoring for SSc-CM &amp; its complications. The association of ECV with lower lipids/WHR, &amp; LGE with lower BMI/sysBP is new &amp; we postulate may reflect cachexia/medication use in severe disease. <h3>Disclosure of Interest</h3> None declared
Updated Results from a Phase II Study of Galiximab (Anti-CD80) in Combination with Rituximab for Relapsed or Refractory, Follicular NHL.
Authors: Jonathan W. Friedberg, John P. Leonard, Anas Younes, David C. Fisher, Leo I. Gordon, Joseph O. Moore, Myron S. Czuczman, Thomas P. Miller, Patrick J. Stiff, Bruce D. Cheson, Andres Forero-Torres, Deborah M. Finucane, Bryan R. Leigh, Arturo Molina
Journal: Blood (2005)
PTH-143 Management of Patients with Hereditary Haemochromatosis (HH) A Single Institution’s Experience
Authors: I Koutsavlis, S Mitchell, A MacGilchrist
Journal: Gut (2016)

<h3>Introduction</h3> HH is a common inherited disorder of iron metabolism. We reviewed risk factors for cirrhosis, screening tests, rates of end organ damage and the outcome of patients treated with venesection. <h3>Methods</h3> A retrospective analysis of 167 patients with HH in the Royal Infirmary of Edinburgh attending the venesection service in 2013 and 2014. <h3>Results</h3> 118 males and 49 females were identified with a mean age of 56 (range 19–83). 79 (47%) had end-organ involvement at presentation: 18% cirrhosis, 17% endocrine, 10% arthropathy, 1% cardiac, 1% skin. The most common endocrine problems were diabetes and hypogonadotropic hypogonadism. Arthropathy was generalised and mostly involved the small joints. 50% had deranged liver function tests (LFTs) at diagnosis. With therapeutic venesection, LFTs improved in 93% whereas arthropathy improved in only 31%. Of the 30 patients with cirrhosis, 26 had serum ferritin (SF) &gt;1000 μg/L at presentation, 25 were C282Y homozygotes, 3 cases progressed to hepatocellular carcinoma, 22 had other risk factors for liver disease [2 Hepatitis C, 13 alcohol and 7 non-alcoholic fatty liver disease (NAFLD)]. Serum Hyaluronic acid (HA), an indicator of hepatic fibrosis, was measured in 73 patients: a normal level reliably excluded cirrhosis [negative predictive value 97.8% (CI 88.7 to 99.9%)]. After completion of the therapeutic phase (SF &lt; 100 μg/L), subsequent venesection requirements were variable: 9 patients did not require venesection for more than 1 year. With a median follow-up of 6 years, no uncomplicated cases at presentation venesected per protocol developed end organ damage. <h3>Conclusion</h3> It is important to identify patients with cirrhosis, particularly if other risk factors for liver disease are present. HA is a useful screening test for cirrhosis in this setting. Protocol venesection is highly successful in preventing end-organ damage: uncomplicated patients at presentation would be suitable for a virtual clinic to lessen the burden on out-patient services. <h3>Disclosure of Interest</h3> None Declared
Loss of Titan (Samd9L), a Candidate -7/7q- Responsible Gene Encoding An Actin Remodeling Regulator, Develops MDS/AML in Cooperation with Evi1 or Fbxl10.
Authors: Hirotaka Matsui, Akiko Nagamachi, Yuko Ozaki, Daisuke Aki, Hiroya Asou, Hiroaki Honda, Toshiya Inaba
Journal: Blood (2009)
miRNA Profiling of Pediatric ALL and Non-Hodgkin Lymphomas.
Authors: Pablo Landgraf, Amanda Rice, Nicola Iovino, Valerio Fulci, Robert Sheridan, Uta Fuchs, Irene Schmid, Chris Sander, Minchen Chen, James J. Russo, Jungyue Ju, Wayne Tam, Giuseppe Macino, Mihaela Zavolan, Arndt Borkhardt, Thomas Tuschl
Journal: Blood (2005)
STAT3 Is Required for Notch-Induced Leukemogenesis, and Functions As a Critical Survival Effector in T-Cell Leukemia
Authors: Jixin Ding, Ana L. Batista, Sonia Rodriguez-Rodriguez, Lin Wang, Wenjun Zhang, Akira Moh, Xin-Yuan Fu, Weinian Shou, Nadia Carlesso, Angelo A Cardoso
Journal: Blood (2011)
Quantitative in vivo X-ray dark-field radiography for early pulmonary emphysema diagnosis
Authors: Katharina Hellbach, Andre Yaroshenko, Felix G. Meinel, Martin Bech, Oliver Eickelberg, Fabian Bamberg, Konstantin Nikolaou, Maximilian F. Reiser, Ali Ö. Yildirim, Franz Pfeiffer
Journal: European Respiratory Journal (2014)

Aims: Using conventional chest X-ray imaging it is hardly possible to visualize early stages of emphysema. The aim of this study was to evaluate whether mild to moderate emphysema can be diagnosed in vivo using X-ray dark-field radiography.  Materials/Methods: Female C57Bl/6N mice were used for the experiments. Emphysema was induced by orotracheal injection of elastase. Control mice received orotracheal injection of PBS. To ensure the development of different stages of emphysema anesthetized and freely breathing mice were scanned 7, 14 and 21 days after application of elastase or PBS. Images were acquired with a prototype grating-based small animal scanner and processed using Fourier decomposition to generate transmission as well as dark-field radiographs. In vivo pulmonary function tests were performed before sacrificing the animals. Lungs were obtained for further histopathological analysis (e.g. mean cord length (MCL-) quantification). Three blinded readers, all of them experienced radiologists who are familiar with dark-field imaging, were asked to stage the severity of emphysema for dark-field and transmission images.  Results: As confirmed by MCL-quantifications lungs in the elastase group had developed different stages of emphysema. Correlation of MCL and dark-field signal intensity (r=0,86) was significantly better than correlation of MCL and transmission signal intensity (r=0,37). Visual ratings for dark-field intensity correlated better with MCL (r=0,82) than those for transmission images (r=0,55).  Conclusion: Using X-ray dark-field radiography it is possible to visualize and diagnose mild to moderate emphysema in vivo with a conventional imaging method for the first time.
SP0145 How To Differentiate Erosions and Vessel Channels
Authors: S. Finzel
Journal: Annals of the Rheumatic Diseases (2016)

Cortical breaks are a common feature in periarticular bone, even in healthy individuals. The true nature of a cortical break sometimes is difficult to determine. Therefore, high-resolution imaging techniques (such as musculoskeletal ultrasound) as well as well profound knowledge of the anatomy are needed in order to not overestimate the amount of pathological cortical breaks (i.e. erosions) and correctly discern them from nutritive vascular channels. The session focusses on pathological and physiological cortical breaks in healthy elderly individuals as well as patients with inflammatory joint diseases such as rheumatoid arthritis and psoriatic arthritis. After the lecture and demonstration the participant should be able to better understand and categorize cortical breaks. <h3>Disclosure of Interest</h3> None declared
Response-Adapted Therapy for Diffuse Large B-Cell Non-Hodgkin's Lymphoma (DLBCL)Based On Early [18F] FDG-PET Scanning: An Eastern Cooperative Oncology Group Study (E3404)
Authors: Lode J. Swinnen, Hailun Li, Andrew Quon, Randy D. Gascoyne, Erik A. Ranheim, Thomas M Habermann, Ranjana H. Advani, Brad S. Kahl, Sandra J. Horning
Journal: Blood (2012)
Comparative efficacy of psychological therapies for improving mental health and daily functioning in irritable bowel syndrome: A systematic review and meta-analysis
Authors: Kelsey T. Laird, Emily E. Tanner-Smith, Alexandra C. Russell, Steven D. Hollon, Lynn S. Walker
Journal: Clinical Psychology Review (2016)

Previous meta-analyses have shown that psychotherapy improves gastrointestinal symptoms in adults with irritable bowel syndrome (IBS); however, the impact on functioning in daily activities is unknown. Meta-analysis was used to estimate the effect of psychotherapy on mental health and daily functioning in adults with IBS. An extensive literature search located 28 eligible randomized controlled trials (RCTs) providing outcome data for mental health and 18 RCTs providing data for daily functioning. Compared to a mixed group of control conditions, psychotherapy produced significantly greater improvements to mental health (d-=0.41) and daily functioning (d-=0.43). Cognitive behavior therapy (CBT) was evaluated in the largest number of trials (21 trials), followed by hypnosis (4 trials), psychodynamic (3 trials), and relaxation (2 trials). The psychotherapeutic modalities were comparable with respect to their effect on mental health. CBT produced the greatest improvements to daily functioning, and this effect was significantly larger than that produced by relaxation therapy. These results have important clinical implications for treatment of adults with IBS.
Frequency and Prognosis of Clonal Chromosomal Abnormalities Following Stem Cell Transplantation (SCT) in Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS)
Authors: Javier Grau, Mireia Morgades, Adela Cisneros, Isabel Granada, Neus Ruiz-Xivillé, Marisol Xandri, Encarnación Santafé, Carmen Villena, Elisa Orna, Lurdes Zamora, Marta Cabezon, Silvia Marce, Jordi Ribera, Blanca Xicoy, Juan Manuel Sancho, Montserrat Batlle, Christelle Ferrà, Susana Vives, Jordi Juncà, Ines Rodriguez, Miriam Moreno, Jose Tomas Navarro, Josep-Maria Ribera, Evarist Feliu, Fuensanta Millá
Journal: Blood (2011)
Treatment-Related Mortality and Relapse Rate from Time of Initiation of Post-Remission Therapy for Patients Receiving Allogeneic Transplantation, Autologous Transplantation or Intensive Chemotherapy: A Report from the Eastern Cooperative Oncology Group (ECOG)
Authors: Jacob M. Rowe, Zhuoxin Sun, Peter A. Cassileth, Frederick R. Appelbaum, Peter H. Wiernik, Hillard M Lazarus, Karl G. Blume, Hugo F. Fernandez, Mark R. Litzow, Martin S Tallman
Journal: Blood (2008)
Efficacy of Allogeneic Hematopoietic Stem Cell Transplantation during First Complete Remission Following Imatinib-Combined Chemotherapy in Patients with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia
Authors: Shuichi Mizuta, Masamitsu Yanada, Isamu Sugiura, Fumiharu Yagasaki, Toshiaki Yujiri, Makoto Takeuchi, Yoshihiro Hatta, Yukihiko Kimura, Yasunori Ueda, Heiwa Kanamori, Noriko Usui, Hideki Akiyama, Yasushi Miyazaki, Shigeki Ohtake, Itsuro Jinnai, Keitaro Matsuo, Tomoki Naoe, Ryuzo Ohno
Journal: Blood (2008)
Mast Cells in the Diffuse Large B-Cell Lymphoma; Their Role for Fibrosis.
Authors: Hiroko Fukushima, Masahiko Ohsawa, Yoshihiro Ikura, Takeshi Inoue, Takahiko Naruko, Nobuyuki Shirai, Yoshimi Sugama, Takehisa Suekane, Chizuko Kitabayashi, Takashi Muraguchi, Masayuki Hino, Makiko Ueda
Journal: Blood (2005)
AB1059 Clinical and Electrophysiological Evaluation of The Effectiveness of Local Insulin Injection in Management of Idiopathic Carpal Tunnel Syndrome (Prospective Study)
Authors: M.H. Abu-Zaid, S. Eid, N. Elgazzar, H. Murad, S. Khodeir
Journal: Annals of the Rheumatic Diseases (2016)

<h3>Background</h3> Carpal tunnel syndrome (CTS) is the most common type of peripheral nerves entrapment; It has a great socioeconomic impact. CTS may be idiopathic or secondary to many causes, especially diabetes mellitus. Insulin has anti-inflammatory effects<sup>1</sup> and the effectiveness of local insulin Injection in diabetic patients with CTS has been previously evaluated <sup>2</sup>. Local insulin Injection in idiopathic CTS has not been studied. <h3>Objectives</h3> To evaluate the effectiveness of local insulin injection as a therapeutic tool in management of idiopathic CTS. <h3>Methods</h3> Twenty eight consecutive hands of mild &amp; moderate idiopathic CTS (diagnosed clinically &amp; electrophysiologically and classified according to American association of neuromuscular diagnostic medicine monograph) received two local injections of 10 IU NPH insulin into the affected carpal tunnel 2 weeks intervals after informed consent. Patients with severe or secondary type of CTS were excluded from this study. Evaluation of the patients at baseline, then at 1 &amp; 3 months after 2nd insulin injection was done clinically [by measuring visual analogue scale (VAS), paraesthesia, Phallen and compression tests] and electrophysiologically (by measuring motor and sensory nerve conduction studies of the median and ulnar nerves using a standardized technique). <h3>Results</h3> Clinically; there was statistically significant improvement in VAS, paraesthesis, Phallen and compression tests at 1 &amp; 3 months after 2nd insulin injection (p&lt;0.01). Electrophysiologically; there was statistically significant improvement in distal motor latency (DML) and distal sensory velocity of median nerve 1 and 3 months after treatment (p&lt;0.01), but the improvement was not statistically significant as regards median distal motor and sensory amplitudes (p&gt;0.05). <h3>Conclusions</h3> Local insulin injection is a promising effective treatment for idiopathic CTS. This is the first study to detect the effect of local insulin injection in idiopathic CTS. <h3>References</h3> Sun Q, Li J, Gao F. New insights into insulin: The anti-inflammatory effect and its clinical relevance. World J Diabetes. 2014 Apr 15; 5(2): 89–96. Ashraf A, Yazdani A, Mirshams S. Evaluation of the effectiveness of local insulin injection in type 2 diabetic patients with CTS. Electromyogr Clin Neurophysiol. 2009 May-Jun;49(4):161–6. <h3>Acknowledgement</h3> Thanks a lot to Dr. Samar Abd Alhamed for her great efforts in completing statistical analysis in this study. <h3>Disclosure of Interest</h3> None declared
SP0076 Prognostic Value of Imaging Markers in Psoriatic Arthritis
Authors: M. Østergaard
Journal: Annals of the Rheumatic Diseases (2016)

Psoriatic arthritis (PsA) is an inflammatory joint disease characterised by arthritis and often enthesitis in patients with psoriasis, but presenting a wide range of disease manifestations in various patterns. Imaging procedures used in PsA are primarily conventional radiography, ultrasonography (US) and magnetic resonance imaging (MRI), whereas other modalities such as computed tomography are not routinely used. Imaging is an integral part of management of psoriatic arthritis for multiple reasons including establishing or confirming the diagnosis, determining extent of disease, monitoring change in disease e.g. activity and damage, assessing therapeutic efficacy, prognostication and identifying complications of disease or treatment, in the setting of clinical practise or clinical studies. These entirely different contexts may favour different imaging approaches. This talk will focus on the available data of different imaging modalities, particularly MRI and US, for predicting 1) the development of psoriatic arthritis in patients with psoriasis, 2) the response to therapy in patients with PsA and 3) the disease course in patients with PsA. <h3>Disclosure of Interest</h3> None declared
DONOR LYMPHOCYTE INFUSIONS (DLI): Risk Factors for Non Relapse Mortality (NRM) In 287 Patients Receiving DLI
Authors: Andrea Bacigalupo, Anna Maria Raiola, Alida Dominietto, Carmen Di Grazia, Francesca Gualandi, Teresa Lamparelli, Stefania Bregante, Francesco Frassoni, Riccardo Varaldo, Silvana Annunziata, Maria Teresa van Lint
Journal: Blood (2010)
Autologous Peripheral Blood Progenitor Cells Cryopreserved in 7.5% DMSO Give Faster Hematopoietic Reconstitution Than Cells Cryopreserved in 10% DMSO.
Authors: Iwona Mitrus, Andrzej Smagur, Sebastian Giebel, Joanna Gliwinska, Magdalena Prokop, Agata Chwieduk, Magdalena Glowala-Kosinska, Maria Sadus-Wojciechowska, Jerzy Holowiecki
Journal: Blood (2012)
Inactivation of the Cell Fate Determinate Llgl1 (Lethal Giant Larvae Homolog 1) Leads to Enhanced HSC Fitness and Predicts a Poor Prognosis in AML.
Authors: Florian H Heidel, Lars Bullinger, Zhu Wang, Patricia Arreba-Tutusaus, Carsten Hirt, Dietger Niederwieser, Konstanze Dohner, Thomas Fischer, Scott A. Armstrong
Journal: Blood (2012)
Effect of Granulocytes Colony Stimulating Factor on Decreased IL-12 p40 Production by Chemotherapy.
Authors: Tomomi Toubai, Junji Tanaka, Shuichi Ota, Takashi Fukuhara, Satoshi Hashino, Takeshi Kondo, Masanobu Morioka, Tsugumichi Kawamura, Nobuo Masauzi, Yasutaka Kakinoki, Hajime Kobayashi, Yasuyuki Kunieda, Masaharu Kasai, Mitsutoshi Kurosawa, Masahiro Imamura
Journal: Blood (2004)
Deubiquitination and Stabilization of PD-L1 by CSN5
Authors: Seung-Oe Lim, Chia-Wei Li, Weiya Xia, Jong-Ho Cha, Li-Chuan Chan, Yun Wu, Shih-Shin Chang, Wan-Chi Lin, Jung-Mao Hsu, Yi-Hsin Hsu, Taewan Kim, Wei-Chao Chang, Jennifer L. Hsu, Hirohito Yamaguchi, Qingqing Ding, Yan Wang, Yi Yang, Chung-Hsuan Chen, Aysegul A. Sahin, Dihua Yu, Gabriel N. Hortobagyi, Mien-Chie Hung
Journal: Cancer Cell (2016)
A 63-Year-Old Man With Progressive Visual Symptoms
Authors: Sara B. Mitchell, Diane Lucente, Mykol Larvie, M. I. Cobos, Matthew Frosch, Bradford C. Dickerson
Journal: JAMA Neurology (2016)

A 63-year-old man presented with a 4-year history of insidious onset and gradual progression of visual symptoms including right homonymous hemianopsia, alexia, and simultanagnosia with preserved memory. Magnetic resonance imaging, perfusion single-photon emission computed tomography, and fluorodeoxyglucose positron emission tomographic scans revealed strikingly asymmetric left parieto-occipital abnormality. Neuropsychological testing was performed. The differential diagnosis, pathologic findings, genetic testing results, and diagnosis are discussed.
Beneficial Prophylactic Antimicrobial Use Against Infectious Complications during Autologous Stem Cell Transplantation: A Result of Randomized Phase II Study in Multiple Myeloma and Non-Hodgkin’s Lymphoma Patients.
Authors: Shin Kim, Yang Hee Cho, Ock Bae Ko, Ja Eun Koo, Danbi Lee, Young Pill Chong, Cheolwon Suh
Journal: Blood (2005)
Autoregulation of MEIS1 through a Distal Enhancer in Acute Leukemia
Authors: Qianfei Wang, Jingfang Dong, Ryan Mattison, Shyam Prabhakar, Fabio Eiji Arimura, Joseph Kaberlein, Chong-zhi Wang, Qianben Wang, Marcelo Nobrega, Michael Thirman
Journal: Blood (2008)