AB1227-HPR Correlations Between Personality Types, Disease Activity and Quality of Life in Ankylosing Spondylitis (AS) Patients (PTS)
Authors: T. Donisan, M.A. Dobrin, D. Predeţeanu, V.C. Bojincă, M. Bojincă, C.L. Constantinescu, D. Opriş, L. Groşeanu, A. Borangiu, F. Berghea, D.V. Bălănescu, R. Ionescu, A.R. Bălănescu
Journal: Annals of the Rheumatic Diseases (2015)

<h3>Background</h3> AS is a disease with a heavy psychological burden<sup>1</sup>, its main clinical characteristics having a profound impact on health related quality of life (HRQoL)<sup>2</sup>. <h3>Objectives</h3> To study the correlations between personality types, health related quality of life (HRQoL) and disease activity in SA, few data being available regarding these aspects. <h3>Methods</h3> This cross-sectional study included 90 AS pts from two different Rheumatology Departments (75.6% men, 24.4% women, mean age 43.63, mean duration of disease 12.7 years). Personality types were assessed with Jenkins Activity Survey (JAS-13) for type A/B, State-Trait Anger Expression Inventory Anger-in Scale (AIS) for type C and Type D Personality Scale (DS-14), with its subcomponents (negative affect-NA and social inhibition-SI) for type D. HRQoL was evaluated using the Medical Outcome Study Short-Term-36 (SF36v2), analyzing correlations with all subscales (Physical function-PF, Social function-SF, Role physical-RP, Role emotional-RE, Mental health-MH, Vitality-VT, Bodily Pain-BP, Global Health-GH, physical component scores-PCS and mental component scores-MCS). Disease activity was assessed with Bath Ankylosing Spondylitis Disease Activity Index (BASDAI). Analyses were performed using Pearson9s correlation coefficients and independent samples t-tests. <h3>Results</h3> Type C pts have lower values of HRQoL components than non-type C (BP <i>t</i>(85)=-2.09, GH <i>t</i>(85)=-2.33, VT <i>t</i>(84)=-2.5, RE <i>t</i>(84)=-2.46, MH <i>t</i>(84)=-2.73, MCS <i>t</i>(84)=-2.61). AIS scores are negatively correlated with all SF36 components (PF <i>r</i>=-0.25, RP <i>r</i>=-0.3, BP<i>r</i>=-0.25, GH <i>r</i>=-0.45, VT <i>r</i>=-0.46, SF <i>r</i>=-0.28, RE <i>r</i>=-0.31, MH <i>r</i>=-0.49, PCS <i>r</i>=-0.26, MCS <i>r</i>=-0.42). Furthermore, type C characteristics increased proportionally with BASDAI values (<i>r</i>=0.33). The same negative tendency was noticed for type D pts, with lower overall values for HRQoL (PF <i>t</i>(85)=-1.98, RP <i>t</i>(68.45)=-2.83, BP <i>t</i>(85)=-2.22, GH <i>t</i>(85)=-3.57, VT <i>t</i>(84)=-3.89, SF <i>t</i>(85)=-2.89, RE <i>t</i>(49.77)=-4.2, MH <i>t</i>(84)=5.51, MCS <i>t</i>(84)=-5.2). Furthermore, type D was found to be inversely proportional with HRQoL, where NA was separately correlated with PF <i>r</i>=-0.41, RP <i>r</i>=-0.38, BP <i>r</i>=-0.39, SF <i>r</i>=-0.47 and PCS <i>r</i>=-0.35, and both type D components (NA and SI) correlated with the other HRQoL components (GH <i>r</i><sub>NA</sub>=-0.57, <i>r</i><sub>SI</sub>=-0.32; VT <i>r</i><sub>NA</sub>=-0.61, <i>r</i><sub>SI</sub>=-0.35; RE <i>r</i><sub>NA</sub>=-0.49, <i>r</i><sub>SI</sub>=-0.31; MH <i>r</i><sub>NA</sub>=-0.67, <i>r</i><sub>SI</sub>=-0.47; MCS <i>r</i><sub>NA</sub>=-0.61, <i>r</i><sub>SI</sub>=-0.39). Type D individuals have higher BASDAI <i>t</i>(84)=2.42, and type D characteristics increase proportionally with BASDAI (<i>r</i><sub>NA</sub>=0.4, <i>r</i><sub>SI</sub>=0.22). When compared to type B, type A pts had overall better physical scores and lower disease activity levels. <h3>Conclusions</h3> Type C and D personalities were found to be strongly correlated with decreased HRQoL and with higher disease activity levels, whereas type A was related to positive results in AS pts. The hypothesis that personality types could influence HRQoL in treatment outcomes should be further analyzed. <h3>References</h3> Martindale J, et al. Rheumatol. 2006;45(10):1288-1293. Baysal Ö, et al. Rheumatol International. 2011;31(6):795-800. <h3>Disclosure of Interest</h3> None declared