AB0280 Depression Affects Negatively Quality of Life Related To Health of Colombian Patients with Rheumatic Arthritis
Authors: M. Peña
Journal: Annals of the Rheumatic Diseases (2016)

<h3>Background</h3> Rheumatic arthritis (RA) causes deterioration on the health-related quality of life (HRQOL) and a negative impact on the emotional sphere of the affected individuals (1). <h3>Objectives</h3> Owing to scarce information existing in Colombia on the subject we decided to know the prevalence of depression on patients with RA and quantify its impact as well as the impacts of other variables on the HRQOL. <h3>Methods</h3> Design of Study: analytical cross sectional study. Population of study: 100 individuals with ages 18 years or more, diagnosed with RA according ACR/EULAR 2010 criteria (2), which attended to outpatient service of the University hospital in the city of Neiva (Colombia) during 2013. Gathering of information (data): through personal surveys that included socio-demographic and clinics variables; evaluation of depression prevalence using the Zung questionnaire (3) and HRQOL using the QOL-RA scale in spanish version (4). Statistical analysis: summary measures, mean with standard deviation were used. An analysis of multiple lineal regression to identify predicter variables of HRQOL was made. For data analysis IBM SPSS 19. version was used. The research project was approved by the bioethical committee of the Universidad Surcolombiana in Neiva. <h3>Results</h3> 84% of participants were women, with mean age 53 years. 85% belong to 1 and 2 (lower) social strata, and 61% live with stable partners, depression prevalence of 23% was found. The mean outcome was 6.38. According dimension, the higher outcomes were familiar support (8.34), social interaction (8.24), and mood (6.49), while the lower outcome were perceived pain (4.97), arthritis (5.01) and physical ability (5.57). Likewise, the patients with depression had significantly lower outcomes of HRQOL (4.94) than those without depression (6.82) (p&lt;0.001). With the multiple lineal regression model the only variable that predicted the HRQOL outcome was depression. <h3>Conclusions</h3> Colombian RA patients have high HRQOL outcomes in social interaction and familiar support dimensions and low in pain and arthritis dimensions; likewise patients with depression had lower HRQOL outcomes than those without depression, indicating that depression affects negatively all dimensions that comprise the QOL-RA scale. HRQOL of Colombian RA patients are negatively influenced by depression, which stresses the importance of early detection and treatment of depressive symptoms in that population. <h3>References</h3> Da Rocha Castelar Pinheiro G, Khandker RK, Sato R, Rose A, Piercy J. Impact of rheumatoid arthritis on quality of life, work productivity and resource utilisation: an observational, cross-sectional study in Brazil. Clin Exp Rheumatol 2013 May-Jun;31(3):334–340. Aletaha D, Neogi T, Silman AJ, et al. 2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Arthritis Rheum 2010;62:2569–81 Zung. WWK. A self-rating depression scale. Arch gen psychiatry. 1965; 12:63–70 Vinaccia S, Fernández H, Moreno E. Aplicaciόn de la versiόn española del cuestionario Quality of Life Measure for Rheumatoid Arthritis (QOL-RA) en Colombia. Revista Colombiana de Reumatología 2006;13(4):264–270. <h3>Acknowledgement</h3> Universidad Nacional de Colombia <h3>Disclosure of Interest</h3> None declared