Principles for Disclosure of Interests and Management of Conflicts in Guidelines: Desirable and Undesirable Action and Consequences
Authors: Holger Schünemann
Journal: Annals of Internal Medicine (2016)

Letters17 May 2016Principles for Disclosure of Interests and Management of Conflicts in Guidelines: Desirable and Undesirable Action and ConsequencesHolger Schünemann, MD, PhD, MScHolger Schünemann, MD, PhD, MScFrom McMaster University, Hamilton, Ontario, Canada.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/L15-0623 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:We thank Drs. Humphrey and MacLellan for their comment. They request that for panel members with indirect COIs, the balance must be in retaining the members in guideline development but ensuring transparency in terms of the nature of the indirect COIs. They also state that the strength of the scientific evidence should inform the recommendations and balance any strong views. We agree and have laid those out in the article as published.We emphasize that transparent processes and evaluating the certainty in (or the strength or quality of) the evidence are key issues in developing trustworthy recommendations (1). ...References1. Schünemann HJ, Wiercioch W, Etxeandia I, Falavigna M, Santesso N, Mustafa R, et al. Guidelines 2.0: systematic development of a comprehensive checklist for a successful guideline enterprise. CMAJ. 2014;186:E123-42. [PMID: 24344144] doi:10.1503/cmaj.131237 CrossrefMedlineGoogle Scholar2. World Health Organization. The Use of Delamanid in the Treatment of Multidrug-Resistant Tuberculosis. Interim Policy Guidance. WHO/HTM/TB/2014.23. Geneva: World Health Organization; 2014. Accessed at http://apps.who.int/iris/bitstream/10665/137334/1/WHO_HTM_TB_2014.23_eng.pdf on 8 December 2014. Google Scholar3. World Health Organization. The Use of Bedaquiline in the Treatment of Multidrug-Resistant Tuberculosis. Interim Policy Guidance. WHO/HTM/TB/2013.6. Geneva: World Health Organization; 2013. Accessed at http://apps.who.int/iris/bitstream/10665/84879/1/9789241505482_eng.pdf on 8 December 2014. Google Scholar Author, Article, and Disclosure InformationAffiliations: From McMaster University, Hamilton, Ontario, Canada.Note: Dr. Schünemann responds on behalf of all of the authors. The following authors confirmed agreement with this response letter by the time of publication: Frode Forland, MD, DPH; Sonja Kersten, MSc; Jorma Komulainen, MD, PhD; Ina B. Kopp, MD; Fergus Macbeth, MA, DM; Susan M. Phillips, BSc (Hons), DPhil; Craig Robbins, MD, MPH; and Amir Qaseem, MD, PhD, MHA.Disclosures: The author is a member of the G-I-N Board of Trustees. No financial interests or relationships exist that are relevant to this response letter. Disclosures can also be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M14-1885. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoGuidelines International Network: Principles for Disclosure of Interests and Management of Conflicts in Guidelines Holger J. Schünemann , Lubna A. Al-Ansary , Frode Forland , Sonja Kersten , Jorma Komulainen , Ina B. Kopp , Fergus Macbeth , Susan M. Phillips , Craig Robbins , Philip van der Wees , Amir Qaseem , and Principles for Disclosure of Interests and Management of Conflicts in Guidelines: Desirable and Undesirable Action and Consequences Brian F. Leas and Craig A. Umscheid Principles for Disclosure of Interests and Management of Conflicts in Guidelines: Desirable and Undesirable Action and Consequences Hilary Humphreys and Kathleen MacLellan Metrics Cited byAmerican Society of Hematology 2020 guidelines for management of venous thromboembolism: treatment of deep vein thrombosis and pulmonary embolism 17 May 2016Volume 164, Issue 10Page: 702KeywordsDisclosureTreatment guidelines ePublished: 17 May 2016 Issue Published: 17 May 2016 Copyright & PermissionsCopyright © 2016 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...