tbuckley/cabot-search huggingface dataset:
How to react to the Orlando massacre?
Authors: Douglas Kamerow
Journal: BMJ (2016)

Harm reduction may have something to offer

In the aftermath of the awful killings at an Orlando gay nightclub early on the morning of 12 June, we are numbed and left searching for answers. Who did it? Why? What could have been done to prevent the massacre? How can we protect “soft” targets like nightclubs (and schools, offices, and shops) from future attacks?

This was clearly a hate crime in addition to a terrorist act. Omar Mir Seddique Mateen had contacted other gay nightclubs as he methodically planned his attack. He called police directly from the nightclub to pledge his support to the Islamic State organization (ISIS), known for its antipathy to gay people in particular as well as …
Endoscopic closure of tracheoesophageal fistula with submucosal dissection and a biosynthetic mesh
Authors: Iago Rodríguez-Lago, Marc Schroeven, Daniel Rodenstein, Pierre Deprez
Journal: Endoscopy (2015)

A 67-year-old female patient was evaluated at the Hepatogastroenterology Department for the management of a chronic tracheoesophageal fistula. She had previously undergone a right lobectomy for congenital bronchiectasis, an aortic valve replacement, and a laparoscopic Heller myotomy with Toupet fundoplication for achalasia. In the past, she had also been admitted to the intensive care unit several times because of respiratory tract infections that required mechanical ventilation.
QOS-20INITIAL PRESENTATION OF CHILDREN WITH BRAIN TUMORS AT A SINGLE INSTITUTION IN JAPAN
Authors: Yuji Yamada, Daiki Kobayashi, Keita Terashima, Ryuji Sasaki, Nobuaki Michihata, Hideki Ogiwara, Kimikazu Matsumoto, Akira Ishiguro
Journal: Neuro-Oncology (2016)
Case 13-1989
Authors: Richard C. Cabot, Robert E. Scully, Eugene J. Mark, William F. McNeely, Betty U. McNeely, Thomas D. Brower, Andrew E. Rosenberg
Journal: New England Journal of Medicine (1989)

Presentation of CaseA 76-year-old woman was admitted to the hospital because of pain about the right hip.There was a history of the radiographic detection of osteosclerotic lesions of the lumbosacral spine, pelvis, right femur, and ribs; some of the lesions were observed at least 29 years earlier, showed little change over the years, and were ascribed to fibrous dysplasia. Five months before admission the patient began to experience pain about the right hip and buttock, with radiation to the right thigh. During several months preceding entry she lost 7 kg in weight, and she experienced anorexia for a . . .
Experimental Impairment of the Gastric Mucous Barrier in Dogs&lt;xref ref-type="fn" rid="fn1"&gt;&lt;sup&gt;1&lt;/sup&gt;&lt;/xref&gt;
Authors: Franklin Hollander, B. P. Sonnenblick, Herbert A. Sober
Journal: JNCI Journal of the National Cancer Institute (1947)

Journal Article Experimental Impairment of the Gastric Mucous Barrier in Dogs Get access Franklin Hollander, Franklin Hollander Gastroenterology Research Laboratory, The Mount Sinai Hospital, New York City Search for other works by this author on: Oxford Academic PubMed Google Scholar B. P. Sonnenblick, B. P. Sonnenblick Gastroenterology Research Laboratory, The Mount Sinai Hospital, New York City Search for other works by this author on: Oxford Academic PubMed Google Scholar Herbert A. Sober Herbert A. Sober Gastroenterology Research Laboratory, The Mount Sinai Hospital, New York City Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 7, Issue 5, April 1947, Pages 361–364, https://doi.org/10.1093/jnci/7.5.361 Published: 01 April 1947
EPT-01DOSE-FINDING STUDY OF VINBLASTINE IN COMBINATION WITH NILOTINIB IN CHILDREN, ADOLESCENTS AND YOUNG ADULTS WITH REFRACTORY OR RECURRENT LOW-GRADE GLIOMA: RESULTS OF THE ITCC/SIOPE-BRAIN VINILO PHASE I TRIAL (NCT01887522)
Authors: Jacques Grill, Marie-Cecile Le Deley, Gwenael Le Teuff, Samuel Abbou, Birgit Geoerger, Francisco Bautista-Sirvent, Katia Malekzadeh, Angelo Paci, Emilie De Carli, Anne-Isabelle Bertozzi, Anne Pagnier, Francois Doz, Pierre Leblond, Frederic Millot, Christelle Dufour, Claire Berger, Fanny Fouyssac, Karsten Nysom, Gilles Vassal
Journal: Neuro-Oncology (2016)
CMS-08NEUROPSYCHOLOGICAL FUNCTIONING IN CHILDREN WITH MEDULLOBLASTOMA: THE IMPACT OF CEREBELLAR MUTISM WITHIN THE FIRST YEAR FOLLOWING DIAGNOSIS
Authors: Karin Walsh, Kristina Hardy, Leanne Embry, Robert Annett, Eugene Hwang, Karin Muraszko, Stephanie Perkins, Jeff Michalski, Robert Noll
Journal: Neuro-Oncology (2016)
Hypertrophic Cardiomyopathy and Sudden Death
Authors: M Piccininno, P Spirito
Journal: New England Journal of Medicine (1988)

Hypertrophic cardiomyopathy is a primary and usually familial cardiac disorder characterized by a genetic, pathophysiologic and clinical complexity. The natural history of the disease is extremely heterogenous: many patients have no or mild symptoms and a near-normal longevity, some develop severe symptoms of heart failure, and others die suddenly often at a young age and in the absence of previous symptoms. Although sudden and unexpected cardiac death may occur at any age in hypertrophic cardiomyopathy, this devastating event is the most common modality of death in children and young patients. Despite intense investigation, risk stratification remains a major challenge. This paper examines the present knowledge on risk assessment and treatment strategies for the prevention of sudden death.
Abstract 16883: Validation of Readmission Risk Score and Readmission Rate in Heart Failure Patients at a Quaternary Hospital
Authors: Selvin Sudhakar, Alejandro N Barbagelata, Saleh Elsaid, Manju Mahajan, Anusha Sunkara, Nischala Nannapanneni, Wei Zhang, Sireesha Garikipatti, Marek Cena, Sara Javed, Hammad Qureshi, Gulshan Sharma
Journal: Circulation (2013)

Background: Heart failure is the most common cause of readmission. Among different methods of identifying patients with risk of readmission, Readmission Risk Calculator® smart phone application dev...
HG-48INTEGRATED SEQUENCING OF PEDIATRIC PILOCYTIC ASTROCYTOMA WITH ANAPLASIA REVEALS MOLECULAR FEATURES OF BOTH LOW AND HIGH-GRADE GLIAL TUMORS
Authors: Frank Y. Lin, Enrique Ramos, Jacquelyn Reuther, Abhishek Bavle, Oliver Hampton, Valentin V. Barsan, David A. Wheeler, Sandi K. Lam, Arnold Paulino, Jack M. Su, Murali M. Chintagumpala, Sharon E. Plon, Angshumoy Roy, Adekunle M. Adesina, D. Williams Parsons
Journal: Neuro-Oncology (2016)
Encephalitozoon Infection in Laboratory Animals&lt;xref ref-type="fn" rid="FN1"&gt;1&lt;/xref&gt;
Authors: Donald H. Yost
Journal: JNCI Journal of the National Cancer Institute (1958)

Encephalitozoon Infection in Laboratory Animals Get access Donald H. Yost Donald H. Yost Captain, VC Biophysics Division, Chemical Warfare Laboratories, Army Chemical Center, Edgewood, Maryland Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 20, Issue 5, May 1958, Pages 957–963, https://doi.org/10.1093/jnci/20.5.957 Published: 01 May 1958
Roux-en-Y gastric bypass surgery of morbidly obese patients induces swift and persistent changes of the individual gut microbiota
Authors: Albert Palleja, Alireza Kashani, Kristine H. Allin, Trine Nielsen, Chenchen Zhang, Yin Li, Thorsten Brach, Suisha Liang, Qiang Feng, Nils Bruun Jørgensen, Kirstine N. Bojsen-Møller, Carsten Dirksen, Kristoffer S. Burgdorf, Jens J. Holst, Sten Madsbad, Jun Wang, Oluf Pedersen, Torben Hansen, Manimozhiyan Arumugam
Journal: Genome Medicine (2016)

Roux-en-Y gastric bypass (RYGB) is an effective means to achieve sustained weight loss for morbidly obese individuals. Besides rapid weight reduction, patients achieve major improvements of insulin sensitivity and glucose homeostasis. Dysbiosis of gut microbiota has been associated with obesity and some of its co-morbidities, like type 2 diabetes, and major changes of gut microbial communities have been hypothesized to mediate part of the beneficial metabolic effects observed after RYGB. Here we describe changes in gut microbial taxonomic composition and functional potential following RYGB. We recruited 13 morbidly obese patients who underwent RYGB, carefully phenotyped them, and had their gut microbiomes quantified before (n = 13) and 3 months (n = 12) and 12 months (n = 8) after RYGB. Following shotgun metagenomic sequencing of the fecal microbial DNA purified from stools, we characterized the gut microbial composition at species and gene levels followed by functional annotation. In parallel with the weight loss and metabolic improvements, gut microbial diversity increased within the first 3 months after RYGB and remained high 1 year later. RYGB led to altered relative abundances of 31 species (P < 0.05, q < 0.15) within the first 3 months, including those of Escherichia coli, Klebsiella pneumoniae, Veillonella spp., Streptococcus spp., Alistipes spp., and Akkermansia muciniphila. Sixteen of these species maintained their altered relative abundances during the following 9 months. Interestingly, Faecalibacterium prausnitzii was the only species that decreased in relative abundance. Fifty-three microbial functional modules increased their relative abundance between baseline and 3 months (P < 0.05, q < 0.17). These functional changes included increased potential (i) to assimilate multiple energy sources using transporters and phosphotransferase systems, (ii) to use aerobic respiration, (iii) to shift from protein degradation to putrefaction, and (iv) to use amino acids and fatty acids as energy sources. Within 3 months after morbidly obese individuals had undergone RYGB, their gut microbiota featured an increased diversity, an altered composition, an increased potential for oxygen tolerance, and an increased potential for microbial utilization of macro- and micro-nutrients. These changes were maintained for the first year post-RYGB. Current controlled trials (ID NCT00810823 , NCT01579981 , and NCT01993511 ).
Acute painful breast in a non-lactating woman
Authors: Jessamy Bagenal, Janani Bodhinayake, Kathryn E Williams
Journal: BMJ (2016)

#### What you need to know

A 50 year old woman describes a three day history of a painful right breast.

Non-lactating women may present with a painful red breast because of periductal inflammation, which can evolve into a breast abscess. This condition must be differentiated from inflammatory breast cancer, a rare type of breast cancer that mimics the signs and symptoms of mastitis (table 1⇓).

View this table:

Table 1 
Differentiation of inflammatory breast cancer from mastitis or breast abscess



Smoking is the main predisposing factor for periductal mastitis due to ductal damage (relative risk from 6.2 to 26.4 for heavy smokers).1 2 3 There is usually an infective element; commonly Staphylococcus aureus , enterococci, or Bacteroides . Poor hygiene and lower socioeconomic status are associated with breast abscess.4

### History

Pain of mastitis typically starts over hours to days—typical symptoms are …
Soundings: Passing out parade
Authors: Colin Douglas
Journal: BMJ (2001)

I wrote one myself once, when a friend of more than 30 years drowned on holiday, in high summer and at the peak of his formidable powers. Most aren't like that. They tell of longer lives: of careers—whether glorious, dutiful, or just humdrum—that went the distance; of retirements enriched by strange pastimes; and of final illnesses. They remind us we must die.

But they are also vivifying. Each week offers a gallery of portraits of lives mostly unknown until over. And the pleasures they elicit are not voyeuristic, but those of the vast enjoyable diversity of our profession, and of our common humanity.

Even colleagues we thought we knew quite well surprise us when they are gone. A modest and kindly obstetrician, later a dean, is posthumously revealed as a wartime hero, a ship's doctor imperturbable on a burning destroyer. Thus his Distinguished Service Cross is explained, along with his calm, wry management of the worst that any faculty committee could throw at him. And a more peppery senior colleague can be forgiven a little now that the details of a sadly deprived childhood (Eton, also during the war) have surfaced.

But it is the strangers who intrigue us most: the aspiring actuary who switched to medicine, practised in the wilds of Canada, and trained as a pilot (fixed wing and helicopter); the paediatrician who made Calman reforms work “through his effective mix of lucidity, assertiveness, and humour,” and in his retirement composed a guitar concerto; and the psychiatrist who pioneered home treatment for patients with severe mental illness, “and thought nothing of helping them with their housework while conducting expert psychiatric assessment.”

Three brief lives, all from one batch of BMJ obituaries (BMJ 2001;323:696), with so many more to relish over the years. They are our folklore, our collective memory, our most dignified of gossip columns, and—for those of us for whom the appeal of the job advertisements has long faded—a treat to look forward to each week.

Now, like a lot else in the BMJ, obituaries have changed: more and shorter, with longer versions on the website for those who wish further details. I have only one further suggestion. They offer so much that their role in our professional development should now be properly recognised: by a modest award—to be claimed on visiting and perusing the website—of CME points.
"JUMPING FRENCHMEN OF MAINE"
Authors: V A MCKUSICK
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
NS-25IMPACT OF MEDULLOBLASTOMA MOLECULAR SUBGROUP ON POST-OPERATIVE PSEUDOMENINGOCELE AND NEED FOR VENTRICULAR SHUNTING
Authors: Giacomo Esposito, Vito Andrea dell'Anna, Antonio Marrazzo, Andrea Carai, Raffaella Messina, Alessandro De Benedictis, Franco Randi, Antonella Cacchione, Evelina Miele, Giovanna Stefania Colafati, Assunta Tornesello, Agnese Po, Elisabetta Ferretti, Angela Mastronuzzi, Marco Maria Fontanella, Carlo Efisio Marras
Journal: Neuro-Oncology (2016)
Initiative is launched to map state level disease burden in India
Authors: Cheryl Travasso
Journal: BMJ (2015)

A collaborative initiative has been launched to estimate the burden of disease and risk factors in individual states of India to help improve planning and health programmes.

Collecting local data is crucial in a country as heterogeneous as India, as national level data do not have sufficient details of local population health to guide targeted approaches and policy. The state level estimations will provide valuable evidence based information on the burden, the target group at risk, changing trends, and the timing and intervention needed to improve health outcomes.

The initiative will be a collaborative effort by the Ministry of …
RICKETS AND TETANY
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
MB-93A NOVEL 3D MODEL OF MEDULLOBLASTOMA METASTASIS CONFIRMS A TWIST1 DRIVEN EMT-LIKE PROCESS
Authors: Aishah Nasir, Anbarasu Lourdusamy, Hanna Cameron, Cara Valente, Lisa Storer, David Onion, Ramadhan T. Othman, Anna Grabowska, Beth Coyle
Journal: Neuro-Oncology (2016)
Penny Wise
Authors: Michael Melgar
Journal: JAMA (2015)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
NU-09THE VALUE OF ORTHOPTIC LEAD FOR PAEDIATRIC ONCOLOGY OPHTHALMOLOGY CLINICS
Authors: Danielle Guy, Ian Simmons, Susan Picton
Journal: Neuro-Oncology (2016)

NU-09. THE VALUE OF ORTHOPTIC LEAD FOR PAEDIATRIC ONCOLOGY OPHTHALMOLOGY CLINICS Danielle Guy, Ian Simmons, andSusan Picton; Leeds TeachingHospitals trust, Leeds, West Yorkshire, UK To demonstrate the value of Orthoptist led paediatric oncology clinics on reducing clinical pressures on the Paediatric Ophthalmologists and providing consistent accurate visual monitoring to ensure timely treatment intervention for a variety of common paediatric brain and visual pathway conditions. Illustration of the types of conditions being regularly monitored by the orthoptist; Utilisation of appropriately experienced allied health professionals to release Ophthalmologists to make best use of limited resources within the health service; Providing consistency of examiner to ensure small visual changes are promptly noted and results discussed directly with oncology consultants to effect prompt treatment changes. FINDINGS: Utilisation of Lead Orthoptist within paediatric oncology ophthalmology clinics has reduced the demand on paediatric ophthalmologist’s clinic time by the equivalent of approximately 150 appointment slots per year; appointments which can then be utilised by other patients. Improved patient experience due to more than one speciality being covered during the same outpatient visit. Improved communications between oncology and ophthalmology due to timely face-to-face discussions re; patient’s visual changes. Neuro-Oncology 18:iii135–iii138, 2016. doi:10.1093/neuonc/now079.9 #The Author(s) 2016. Published by Oxford University Press on behalf of the Society for Neuro-Oncology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
A Comparison of the Patterns of Excretion and the Carcinogenicity in the Rat of 2-Acetylaminofluorene and Related Compounds&lt;xref ref-type="fn" rid="fn1"&gt;2&lt;/xref&gt;
Authors: H M DYER
Journal: JNCI Journal of the National Cancer Institute (1955)

Journal Article A Comparison of the Patterns of Excretion and the Carcinogenicity in the Rat of 2-Acetylaminofluorene and Related Compounds Get access Helen M. Dyer Helen M. Dyer Laboratory of Biochemistry, Nutrition and Carcinogenesis Section, National Cancer Institute,4Bethesda, Md. Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 16, Issue 1, August 1955, Pages 11–30, https://doi.org/10.1093/jnci/16.1.11 Published: 01 August 1955 Article history Received: 22 November 1954 Published: 01 August 1955
"As Directed"
Authors: John F. Oliven
Journal: JAMA (1974)

<h3>To The Editor.—</h3> In the article by three pharmacists on inadequately written prescriptions (226:999, 1973), the practice of the "as directed" is attacked. It is good to look at the other side of the drug counter at the practitioner's side. For instance, psychiatric prescribing, a proportion of it long-range, is subject to frequent dosage and similar changes throughout the course of treatment, thus making original label inscriptions inapplicable. Experience has shown again and again that such fixed label directions become confusing, especially if the medication has been interrupted for a while and then resumed. Some of us also have had cases where labelling that directs bedtime use of other than sleeping medicine—quite frequent today in psychiatric prescribing—has later led patients or their relatives to dose themselves with various substances for insomnia. It goes without saying that directions should be written out separately for the patient and dated; note-taking is insisted
LMI-08INFANT BRAIN TUMORS IN SINGLE TERTIARY CARE INSTITUTE (SRINAGARIND HOSPITAL, KHON KAEN UNIVERSITY)
Authors: Patcharee Komvilaisak, Amnat Kitkhuandee Kitkhuandee, Surapon Wiangnon Wiangnon, Arunee Jetrisuparb, Pitchayen Oungtongpon, Sakda Waraasawapati
Journal: Neuro-Oncology (2016)

Brain tumor in children less than 3 years is infrequently common but devastating outcome and consequence.In order to improve the outcome, the study is to describe the types of brain tumors and outcome of treatment in children