tbuckley/cabot-search huggingface dataset:
CPAP or non-invasive ventilation in obesity hypoventilation syndrome: does it matter which one you start with?
Authors: Julio R Noda, Juan F Masa, Babak Mokhlesi
Journal: Thorax (2017)

In recent decades, the prevalence of obesity and severe obesity has increased significantly around the globe.1 ,2 As a consequence, it is likely that the prevalence of obesity-associated comorbidities such as obesity hypoventilation syndrome (OHS) will follow the same trend.3 OHS is the most severe form of respiratory compromise induced by obesity, leading to increased mortality and a wide array of comorbidities such as pulmonary hypertension, right heart failure and increased risk of hospitalisation due to acute-on-chronic hypercapnic respiratory failure.4–6 Unfortunately, OHS remains frequently unrecognised or misdiagnosed even in patients with severe obesity hospitalised with hypercapnic respiratory failure.7 ,8

Although positive airway pressure (PAP) remains the cornerstone therapy for OHS, controversy persists as to the preferred mode of PAP therapy for long-term management.9 In theory, non-invasive ventilation (NIV) should be more effective than CPAP since it addresses the various complex pathophysiological disturbances that result in OHS, such as altered ventilatory drive, increased work of breathing due to restrictive chest physiology induced by excess adiposity and exacerbation of hypoventilation during sleep. However, observational and a few randomised controlled trials with short-term follow-up have shown that both CPAP and NIV are equally effective in improving daytime and nighttime hypercapnia as well as symptoms in patients with OHS.10–12 NIV is commonly prescribed as a fixed level of pressure support in the form of bilevel PAP in spontaneous mode or bilevel PAP spontaneous-timed (ST) mode with a back-up respiratory rate, or a variable level of pressure support such as volume-targeted pressure support. Given the lack of consensus and the limited information on long-term outcomes with the various modalities of PAP therapy, it is not surprising that there is significant variation in clinical practice.

To further address this relevant clinical question, Howard et al 13 conducted a …
Abstract 2344: Pressure-guided Cryoballoon Isolation of the Pulmonary Veins for the Treatment of Paroxysmal Atrial Fibrillation
Authors: Claudia Herrera Siklody, Jan Minners, Martin Allgeier, Jurgen Allgeier, Nikolaus Jander, Jochen Schiebeling-Romer, Cornelius Keyl, Reinhold Weber, Dietrich Kalusche, Thomas Arentz
Journal: Circulation (2009)

Background: Pulmonary vein (PV) isolation using a balloon-mounted cryoablation system is a new technology for the percutaneous treatment of atrial fibrillation (AF). Complete PV occlusion during ba...
Inducible Caspase-9 Selectively Modulates the Toxicities of CD19-Specific Chimeric Antigen Receptor-Modified T Cells
Authors: Iulia Diaconu, Brandon Ballard, Ming Zhang, Yuhui Chen, John West, Gianpietro Dotti, Barbara Savoldo
Journal: Molecular Therapy (2017)

Immunotherapy with T cells expressing the chimeric antigen receptor (CAR) specific for the CD19 antigen (CD19.CAR-Ts) is a very effective treatment in B cell lymphoid malignancies. However, B cell aplasia and cytokine release syndrome (CRS) secondary to the infusion of CD19.CAR-Ts remain significant drawbacks. The inclusion of safety switches into the vector encoding the CAR is seen as the safest method to terminate the effects of CD19.CAR-Ts in case of severe toxicities or after achieving long-term sustained remissions. By contrast, the complete elimination of CD19.CAR-Ts when CRS occurs may jeopardize clinical responses as CRS and antitumor activity seem to concur. We have demonstrated, in a humanized mouse model, that the inducible caspase-9 (iC9) safety switch can eliminate CD19.CAR-Ts in a dose-dependent manner, allowing either a selective containment of CD19.CAR-T expansion in case of CRS or complete deletion on demand granting normal B cell reconstitution.
Dysfunctional Tregs with Absence of Cytokine-Secreting CD4+ T-Cell Subsets and Marked Expansion of Th1 Cells Is a Hallmark of Idiopathic Aplastic Anaemia (AA)
Authors: Shahram Kordasti, Judith C. W. Marsh, Pilar Perez Abellan, Sufyan Alkhan, Janet Hayden, Caroline Veen, Jie Jiang, Farzin Farzaneh, Ghulam J. Mufti
Journal: Blood (2010)
Double-blind placebo-controlled randomized clinical trial of verapamil for chronic rhinosinusitis with nasal polyps
Authors: Marcel M. Miyake, Angela Nocera, Patricia Levesque, Rong Guo, Christine A. Finn, Jeremy Goldfarb, Stacey Gray, Eric Holbrook, Nicolas Busaba, Jose Eduardo L. Dolci, Benjamin S. Bleier
Journal: Journal of Allergy and Clinical Immunology (2017)
Tumor Suppressors BTG1 and BTG2 Fulfill Both Unique and Overlapping Functions During Normal B Lymphocyte Development
Authors: Esther J.H. Tijchon, Liesbeth van Emst, Jørn Havinga, Jean-Pierre Rouault, Felice Tirone, Peter M. Hoogerbrugge, Blanca Scheijen, Frank N. van Leeuwen
Journal: Blood (2012)
Campath-IH Combined with Fludarabine/Cyclophophamide/Rituximab (FCR) as Conditioning for Unrelated Non-Myeloablative Hematopoietic Transplantation (NMT) for Non-Hodgkin’s Lymphoma (NHL): Low Mortality Rate and Lower Than Expected Incidence of Cytomegalovirus (CMV) Reactivation.
Authors: Issa F. Khouri, Jeffrey J. Tarrand, Grace-Julia Okoroji, Rima M. Saliba, Chitra M. Hosing, Daniel R. Couriel, Partow Kebriaei, Donna Griffith, Gabriela Rondon, Cindy Ippoliti, Richard E. Champlin
Journal: Blood (2005)
Circulating Levels of Adhesion Molecules and Markers of Endothelial Dysfunction in Acute Inflammation Induced by Prolonged Brisk Exercise: Rapid Endothelial Recovery and Potential Beneficial Effects.
Authors: Ioannis Papassotiriou, Anastasia Bartzeliotou, Alexandra Margeli, Maria Tsironi, Katerina Skenderi, Chryssa Bacoula, George Chrousos
Journal: Blood (2006)
Bryostatin Enhances the Cytotoxic Effects of Anti-CD22 Immunotoxins in CLL by Two Distinct Mechanisms: Implications for a Sequential Therapy.
Authors: Ingo Ringshausen, Thomas Decker, Viola Biberacher, Christian Meyer zum Buschenfelde, Madlen Oelsner, Michaela Wagner, Christian Bogner, Christian Peschel
Journal: Blood (2009)
Genetic Alterations of Wilms' Tumor 1 (WT1) Gene In Korean Patients with Normal Karyotype Acute Myeloid Leukemia
Authors: Yunsuk Choi, Je-Hwan Lee, Jung-Hee Lee, Dae-Young Kim, Sung-Doo Kim, Sung-Nam Lim, Eun-Hye Hur, Miee Seoul, Young-Shin Lee, Young-Ah Kang, Mijin Jeon, Kyoo-Hyung Lee
Journal: Blood (2010)
Impact On Survival and Treatment of Late-Onset Noninfectious Pulmonary Complications After Allogeneic Hematopoietic Stem Cell Transplantation.
Authors: Koki Ueda, Takeyuki Watadani, Eriko Maeda, Satoshi Ota, Keisuke Kataoka, Sachiko Seo, Keiki Kumano, Akira Hangaishi, Tsuyoshi Takahashi, Yoichi Imai, Kuni Ohtomo, Masashi Fukayama, Yasuhito Nannya, Mineo Kurokawa
Journal: Blood (2009)
Three-Dimensional Visualization of Immunological Processes of Entire Organs in Subcellular Resolution.
Authors: Christian Brede, Mike Friedrich, Ana-Laura Jordán-Garrote, Simone S Riedel, Carina A Baeuerlein, Carolin Kiesel, Miriam Ritz, Marina Grether, Rossella Monteforte, Stephan Schulz, Hermann Einsele, Robert S Negrin, Gregory S Harms, Andreas Beilhack
Journal: Blood (2009)
High workload is putting doctors’ professionalism at risk, says GMC
Authors: Tom Moberly
Journal: BMJ (2017)

Doctors’ professionalism is being put at risk by the current pressures on the health service, the chair of the General Medical Council has warned, and he urges doctors to speak out over patient safety concerns.

In his annual message to UK doctors, Terence Stephenson said that doctors were being forced to make difficult decisions about care and losing out on training opportunities because of the pressures on the health service.

“The GMC has no …
Evidence of a cumulative effect for risk factors predicting low bone mass among male adolescent athletes
Authors: Michelle T Barrack, Michael Fredericson, Adam S Tenforde, Aurelia Nattiv
Journal: British Journal of Sports Medicine (2017)

Limited research has evaluated risk factors for low bone mineral density (BMD) in male adolescent athletes.To evaluate predictors of low BMD (defined as BMD Z-score <-1.0) in a sample of male adolescent distance runner and non-runner athletes.Male adolescent athletes completed a survey characterising sports participation, nutrition, stress fracture history, dual energy X-ray absorptiometry (DXA)-measured BMD and body composition. Independent t-tests and analysis of covariance (ANCOVA) evaluated group differences; logistic regression evaluated low BMD risk factors.Runners (n=51) exhibited a lower body weight (p=0.02), body mass index (BMI) (kg/m2) (p=0.02), per cent expected weight (p=0.02) and spine BMD Z-score (p=0.002) compared with non-runners (n=18). Single risk factors of low BMD included <85% expected weight (OR=5.6, 95% CI 1.4 to 22.5) and average weekly mileage >30 in the past year (OR=6.4, 95% CI 1.5 to 27.1). The strongest two-variable and three-variable risk factors included weekly mileage >30+ stress fracture history (OR=17.3, 95% CI 1.6 to 185.6) and weekly mileage >30+<85% expected weight + stress fracture history (OR=17.3, 95% CI 1.6 to 185.6), respectively. Risk factors were cumulative when predicting low BMD (including <85% expected weight, weekly mileage >30, stress fracture history and <1 serving of calcium-rich food/day): 0-1 risk factors (11.1%), 2 risk factors (42.9%), or 3-4 risk factors (80.0%), p<0.001).Male adolescent runners exhibited lower body weight, BMI and spine BMD Z-score values. The risk of low BMD displayed a graded relationship with increasing risk factors, highlighting the importance of using methods to optimise bone mass in this population.
Intrabone Infusion of Umbilical Cord Blood Stem Cells to Improve Hematopoietic Recovery after Allogeneic Umbilical Cord Blood Transplantation in Children
Authors: Henrique Bittencourt, Marie-France Vachon, Isabelle Louis, Ernestine Chablis, Marion Cortier, Edith Villeneuve, Pierre Teira, Sonia Cellot, Elie Haddad, Michel Duval
Journal: Blood (2015)
In refractory chronic cough, physiotherapy plus speech and language therapy improved quality of life at 4 weeks
Authors: Diego J. Maselli, Jay I. Peters
Journal: Annals of Internal Medicine (2017)

Source Citation Chamberlain Mitchell SA, Garrod R, Clark L, et al. Physiotherapy, and speech and language therapy intervention for patients with refractory chronic cough: a multicentre randomised control trial. Thorax. 2016;Sep 28. [Epub ahead of print]. 27682331
NCO-16GENETIC MODULATION OF NEUROCOGNITIVE DECLINE IN GLIOMA PATIENTS
Authors: Jeffrey Wefel, Erik Sulman, Renke Zhou, Yanhong Liu, Michael Scheurer, Melissa Bondy
Journal: Neuro-Oncology (2015)

BACKGROUND: Despite similar treatments, some glioma patients exhibit greater neurotoxicity manifest as worse neurocognitive function (NCF) over time. Identifying genetic risk factors associated with different trajectories of NCF would provide insights into patient subsets with greater or less sensitivity to treatment. METHODS: 102 patients completed neuropsychological testing postoperatively and again at least six months after completion of radiation/chemotherapy. Five neuropsychological tests measuring memory (HVLT-R), processing speed (Trail Making Test A), and executive function (Controlled Oral Word Association, and Trail Making Test B) were examined. To identify the effect of genetic variants on NCF, we compared the genotype frequencies of 9,445 SNPs mapping to 585 genes from five pathways: Inflammation, DNA repair, Metabolism, Neurocognitive, and TERT. Models were adjusted for postoperative NCF test performance, tumor progression, tumor grade, and time. RESULTS: The strongest genetic associations were seen between SNPs in the DNA repair (P = 2.90E-06; P adjusted = 0.002) and Neurocognitive (P = 2.35E-05; P adjusted = 0.009) pathways and Executive Function, and, Inflammation (P = 9.26E-07; P adjusted = 0.004) and TERT (P = 2.24E-07; P adjusted = 0.0001) pathways and Processing Speed. Joint effect analysis found significant gene-dosage effects for Executive Function (P trend = 2.05E-11) and Processing Speed (P trend =1.51E-10). CONCLUSION: After treatment, cognitive decline (particularly Executive Function and Processing Speed) was associated with genetic polymorphisms in genes from Neurocognitive, Inflammation, DNA repair and TERT pathways. Recent clinical trials with NCF testing and serum samples provide an invaluable resource to cross validate and extend these findings in a homogeneous population. Validation may permit precision medicine approaches to therapy including both treatment modifications/neuroprotective strategies to reduce risk of NCF decline as well as treatment intensification to maximize therapeutic benefit when neurotoxicity risk is known to be low.
Structural studies of the green tea catechins, epigallocatechin gallate and epigallocatechin as ternary complexes with NADPH and mouse dihydrofolate reductase
Authors: Vivian Cody, Jim Pace, Edward Snell
Journal: Cancer Research (2007)

3178   Recent studies have shown that the naturally occurring gallated catechins isolated from green tea inhibit dihydrofolate reductase (DHFR) at concentrations found in serum (Cancer Res. 65:2059 (2005)). These data showed characteristics of slow-binding inhibitors of bovine DHFR (Biochem. 44:7512 (2005)). Modeling studies of the catechin binding showed that epigallocatechin gallate (egcg) could occupy the active site in a manner similar to that observed from our structural results of the tetrahydroquinazoline antifolate binary complex with human DHFR (Acta D. 60:646 (2004)). To delineate the binding mechanism of these polyphenols in DHFR, we determined the crystal structures of epigallocatechin (egc) and its gallate derivative (egcg), as NADPH ternary complexes with mouse DHFR, the closest homologue to bovine DHFR. Diffraction data were collected to 1.3A for both monoclinic crystals at the Stanford Synchrotron facility. Refinement of these data is in progress and preliminary refinement models show strong electron density in the active site that show the gallated catechin binds in a manner similar to that proposed from modeling studies. These data also show that both Phe31 and Asn64 adopt alternate conformations than observed in other mouse or human DHFR inhibitor complexes, thereby permitting access to the polyphenol. Further refinement is needed to determine if there are alternate binding modes accessible to the catechin.  Supported by GM51670 (VC).
Cardiothoracic surgeon is struck off for misconduct
Authors: Clare Dyer
Journal: BMJ (2017)

A consultant cardiothoracic surgeon who has not practised since the brief closure of the paediatric heart unit at Leeds General Infirmary in 2013 has been struck off for misconduct in four operations carried out there from 2008 to 2012.

Nihal Weerasena had just voluntarily ceased practising after an internal review at Leeds when the NHS’s medical director, Bruce Keogh, visited in March 2013 with representatives of the Care Quality Commission to respond to concerns expressed by other surgeons and preliminary data that suggested higher than average death rates in the paediatric heart unit.

Children’s heart surgery was stopped for two weeks as recriminations flew in …
APOE Genotype Differentially Modulates Effects of Anti-Aβ, Passive Immunization in APP Transgenic Mice
Authors: Joanna E Pankiewicz, Jairo Baquero-Buitrago, Sandrine Sanchez, Jennifer Lopez-Contreras, Jungsu Kim, Patrick M. Sullivan, David M. Holtzman, Martin J. Sadowski
Journal: Molecular Neurodegeneration (2017)

APOE genotype is the foremost genetic factor modulating β-amyloid (Aβ) deposition and risk of sporadic Alzheimer's disease (AD). Here we investigated how APOE genotype influences response to anti-Aβ immunotherapy. APPSW/PS1dE9 (APP) transgenic mice with targeted replacement of the murine Apoe gene for human APOE alleles received 10D5 anti-Aβ or TY11-15 isotype control antibodies between the ages of 12 and 15 months. Anti-Aβ immunization decreased both the load of fibrillar plaques and the load of Aβ immunopositive plaques in mice of all APOE backgrounds. Although the relative reduction in parenchymal Aβ plaque load was comparable across all APOE genotypes, APP/ε4 mice showed the greatest reduction in the absolute Aβ plaque load values, given their highest baseline. The immunization stimulated phagocytic activation of microglia, which magnitude adjusted for the post-treatment plaque load was the greatest in APP/ε4 mice implying association between the ε4 allele and impaired Aβ phagocytosis. Perivascular hemosiderin deposits reflecting ensued microhemorrhages were associated with vascular Aβ (VAβ) and ubiquitously present in control mice of all APOE genotypes, although in APP/ε3 mice their incidence was the lowest. Anti-Aβ immunization significantly reduced VAβ burden but increased the number of hemosiderin deposits across all APOE genotypes with the strongest and the weakest effect in APP/ε2 and APP/ε3 mice, respectively. Our studies indicate that APOE genotype differentially modulates microglia activation and Aβ plaque load reduction during anti-Aβ immunotherapy. The APOE ε3 allele shows strong protective effect against immunotherapy associated microhemorrhages; while, conversely, the APOE ε2 allele increases risk thereof.
Screening for Obstructive Sleep Apnea
Authors: Susan Redline
Journal: JAMA (2017)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hematopoietic Cell Transplantation after TBI, Fludarabine, Idarubicine and Cytarabine Myeloablative Conditioning in Patients with Acute Myeloid Leukemia
Authors: Jan Vydra, Veronika Válková, Markéta ťastná Marková, Ludmila Nováková, Jiří Schwarz, Cyril álek, Antonín Vítek, Petr Cetkovský, Jaroslav Čermák, Kyra Michalová
Journal: Blood (2014)
Programmed cell death‐1 expression correlates with disease severity and IL‐5 in chronic rhinosinusitis with nasal polyps
Authors: I. Kortekaas Krohn, S. Bobic, J. Dooley, F. Lan, N. Zhang, C. Bachert, B. Steelant, D. M. Bullens, A. Liston, J. L. Ceuppens, S. F. Seys, P. W. Hellings
Journal: Allergy (2017)

Abstract Background Programmed cell death‐1 (PD‐1) is a negative regulator of T‐cell responses. Expression of PD‐1 and its ligands PD‐L1 and PD‐L2 in chronic rhinosinusitis with nasal polyps (CRSwNP) is poorly studied. Methods Expression of PD‐1, PD‐L1, PD‐L2, TGF‐β, IL‐5, and IL‐10 mRNA was measured by real‐time quantitative PCR on tissue homogenates of patients with CRSwNP ( n = 21) and healthy controls ( n = 21) and on primary epithelial cells. Disease severity was scored using the Lund–Mackay scores of maxillofacial computed tomography (CT) scans. Expression of PD‐1 and PD‐L1/L2 was evaluated at the cellular and tissue levels ( n = 6) by flow cytometry and immunohistochemistry. Results Programmed cell death‐1 mRNA expression was increased in tissue homogenates from patients with CRSwNP compared with controls, irrespective of the atopy status. Importantly, expression of PD‐1 correlated with the total CT scan scores ( r = 0.5, P = 0.02). Additionally, a significant association was found between PD‐1 mRNA and expression of IL‐5 mRNA in control nasal tissue ( r = 0.95, P &lt; 0.0001) and in CRSwNP ( r = 0.63, P = 0.002). PD‐1 was expressed on different subsets of T cells and CD11b − dendritic cells. Both PD‐1 and its ligands were expressed on primary epithelial cells from control nasal tissue and nasal polyp tissue. Conclusions Higher PD‐1 expression was found in CRSwNP than in nasal tissue from controls. This was associated with disease severity and tissue IL‐5 expression but unrelated to the patients' atopy status.
A Missed Opportunity to Discuss Racial and Gender Bias in Dermatology
Authors: Adewole S. Adamson, Sylvia W. Wright, Amit G. Pandya
Journal: JAMA Dermatology (2017)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Dermatology HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Dermatology journal
Staphylococcus Species Leads the Eskape Infections in Various Hematological Malignancies
Authors: Purnima Sravanti Teegavarapu, Mamta Puppala, Sai Ravi Pingali, Asmita Patel, Ibrahim Ibrahim, Akash Mukherjee, Lawrence Rice, Swaminathan Padmanabhan Iyer
Journal: Blood (2015)
Graft-Vs-Leukemia Effects of Allogeneic Stem Cell Transplantation from HLA-Haploidentical Family Members as Compared to HLA-Identical Sibling Donors
Authors: Hans Jochem Kolb, Iris Bigalke, Dominik Termeer, Susanne Fritsch, Wolfgang Hill, Belinda Simoes, Andreas Hausmann, Christine Falk, Raymund Buhmann, Johanna Tischer, Georg Ledderose
Journal: Blood (2008)
Rituximab Sensitivity to De Novo DLBCL Cells Showing the Specific Phenotype of CD20 Protein Immunohistochemistry-Positive / Flow Cytometory-Negative: Analyses of Its Clinical Significances and the Molecular Mechanisms.
Authors: Akihiro Tomita, Takashi Tokunaga, Tatsuya Hirose, Keiki Sugimoto, Kazuyuki Shimada, Norio Kaneda, Hitoshi Kiyoi, Naoko Asano, Shigeo Nakamura, Tomohiro Kinoshita, Tomoki Naoe
Journal: Blood (2012)
Mediterranean diet and risk of heart failure: results from the PREDIMED randomized controlled trial
Authors: Angeliki Papadaki, Miguel Ángel Martínez‐González, Angel Alonso‐Gómez, Javier Rekondo, Jordi Salas‐Salvadó, Dolores Corella, Emilio Ros, Montse Fitó, Ramon Estruch, José Lapetra, Antonio García‐Rodriguez, Miquel Fiol, Lluís Serra‐Majem, Xavier Pintó, Miguel Ruiz‐Canela, Monica Bulló, Mercè Serra‐Mir, Jose V. Sorlí, Fernando Arós
Journal: European Journal of Heart Failure (2017)
Molecular Genetics of Hereditary Prothrombin Deficiency in Indian Patients: Identification of a Novel Ala362→Thr (Prothrombin Vellore 1) Mutation by Conformation Sensitive Gel Electrophoresis.
Authors: G Jayandharan, R.V. Shaji, Auro Viswabandhya, Sukesh C. Nair, Joy Mammen, Biju George, Vikram Mathews, Mammen Chandy, Alok Srivastava
Journal: Blood (2004)