tbuckley/cabot-search huggingface dataset:
Surgery, Its Principles and Practice. For Students and Practitioners.
Journal: JAMA (1928)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
DRUG ADDICTION IN THE UNITED STATES
Authors: C Piña
Journal: JAMA (1924)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Myocardial Structural and Functional Response After Long-Term Mechanical Unloading With Continuous Flow Left Ventricular Assist Device
Authors: Mohammad Al-Sarie, Asad Rauf, Abdallah G. Kfoury, Anna Catino, James Wever-Pinzon, Michael Bonios, Benjamin D. Horne, Nikolaos A. Diakos, Omar Wever-Pinzon, Stephen H. McKellar, Aaron Kelkhoff, Lauren McCreath, James Fang, Josef Stehlik, Craig H. Selzman, Stavros G. Drakos
Journal: JACC Heart Failure (2016)
MB-70MEMMAT - A PHASE II STUDY OF METRONOMIC AND TARGETED ANTI-ANGIOGENESIS THERAPY FOR CHILDREN WITH RECURRENT/PROGRESSIVE MEDULLOBLASTOMA
Authors: Andreas Peyrl, Monika Chocholous, Amedeo Azizi, Mark Kieran, Karsten Nysom, Jaroslav Sterba, Magnus Sabel, Thomas Czech, Karin Dieckmann, Christine Haberler, Maresa Schmook, Ulrike Leiss, Irene Slavc
Journal: Neuro-Oncology (2016)
Genetic risk factors for sclerotic graft-versus-host disease
Authors: Yoshihiro Inamoto, Paul J. Martin, Mary E. D. Flowers, Stephanie J. Lee, Paul A. Carpenter, Edus H. Warren, Daniel E. Geraghty, Ni Lee, Michael J. Boeckh, Barry E. Storer, David M. Levine, Wenhong Fan, Lue-Ping Zhao, John A. Hansen
Journal: Blood (2016)
Carefully executed studies of illness in elite sport: still room to improve methods in at least five ways
Authors: Hilde Moseby Berge, Ben Clarsen
Journal: British Journal of Sports Medicine (2016)

In the first1 of our two editorials we discussed if cross-country skiers were more prone to illness than soccer players, illustrated by the carefully executed studies of illness by Svendsen et al 2 and Bjorneboe et al .3 In this second editorial, we discuss why counting and comparing numbers in these kind of studies are associated with methodological challenges.

In the cross-country skiing study, Svendsen et al counted an infectious event whenever an athlete reported one or more symptoms on two or more consecutive days. In the soccer study, Bjorneboe et al counted an illness episode as any physical or psychological symptom that resulted in the player being unable to participate fully in training or match play. In studies reporting incidence of illness during the Olympic and Paralympic Games, any athlete requiring medical attention was counted.2 ,3 These definitions appear to have simply replaced injuries by illness in the same context.4 Maybe that …
Influenza: Preparedness for an Inevitable “Emergency” for Oncology and BMT Units
Authors: John R. Wingard
Journal: Journal of the National Comprehensive Cancer Network (2008)

Influenza is a seasonal and pandemic threat to the general population. The effects can be devastating for cancer patients and those who have undergone blood and marrow transplantation (BMT). However, this impact can be minimized. Emergency preparedness is the key to mitigating the impact on the oncology and BMT services. Having a plan that provides a framework of preparedness and outlines steps to take in the event of a community outbreak is crucial. A vigorous immunization campaign for patients, household contacts, and health care staff early in the season is the single most important action. In the midst of an outbreak, the oncology and BMT teams should act to quickly identify patients with suspected infections, move infected patients and staff away from noninfected patients to prevent contact, and decide which patients require prevention or treatment with antiviral agents. Ongoing engagement by the entire team to evaluate the effectiveness of its actions and modify its plan as necessary will ensure success.
Endomyocardial <scp>miR</scp>‐133a levels correlate with myocardial inflammation, improved left ventricular function, and clinical outcome in patients with inflammatory cardiomyopathy
Authors: Christian Besler, Daniel Urban, Stefan Watzka, David Lang, Karl‐Philipp Rommel, Reinhard Kandolf, Karin Klingel, Holger Thiele, Axel Linke, Gerhard Schuler, Volker Adams, Philipp Lurz
Journal: European Journal of Heart Failure (2016)
Two Years Clinical Experiences with Extracorporeal Shock-Wave Lithotripsy and Transurethral Ureterolithotripsy for Ureteral Stones at Osaka City University Hospital
Authors: Taketoshi Kishimoto,, Keisuke Yamamoto,, Toshikado Sugimoto,, Kazunobu Sugimura,, Tatsuya Nakatani, Seiji Wada, Sinichi Ikemoto, Muneki Umori, Masaaki Senju, Toshinao Kanazawa, Masanobu Maekawa
Journal: European Urology (1989)
Trans-fistulary endoscopic drainage for post-bariatric abdominal collections communicating with the upper gastrointestinal tract
Authors: Simon Bouchard, Pierre Eisendrath, Emmanuel Toussaint, Olivier Le Moine, Arnaud Lemmers, Marianna Arvanitakis, Jacques Devière
Journal: Endoscopy (2016)

<b>Background and study aims:</b> Diverse endoscopic methods, such as placement of temporary self-expandable stents, have proven effective for the treatment of post-bariatric surgery leaks. However, some patients do not respond to the usual endoscopic treatment. This study tested the efficacy of an alternative treatment strategy based on trans-fistulary drainage with double-pigtail plastic stents. <b>Patients and methods:</b> We performed a retrospective analysis of patients with abdominal collections following bariatric surgery who were treated by trans-fistulary stenting between May 2007 and February 2015. Clinical success was defined as a sustained (> 4 months) clinical resolution (patient discharged from the hospital without antibiotics and able to resume a normal diet) and radiological response. Patient records, radiological images, and the hospital endoscopy database were reviewed. <b>Results:</b> A total of 33 patients (26 women/7 men, mean age 42 years [SD 11.2]) were included. Collections occurred after sleeve gastrectomy (n = 28) or after gastric bypass (n = 5). Fourteen patients were treated by trans-fistulary stenting as primary treatment, and 19 patients had undergone previous unsuccessful endoscopic treatment. No serious complication occurred during the drainage procedure. Clinical success was achieved in 26 patients (78.8 %). In two successfully treated patients, stents are still in place. Spontaneous stent migration occurred in 12 patients. In 12 patients, the stents were removed, either electively (n = 5) or because of complications (ulcerations n = 3, upper gastrointestinal symptoms n = 3, splenic hematoma n = 1). <b>Conclusions:</b> Trans-fistulary drainage of post-bariatric abdominal collections is safe and associated with high success rates. This technique can be considered in previously untreated patients, when a collection is not properly drained percutaneously, or after failure of other endoscopic treatments.
Serum prolactin levels in sons of alcoholics and control subjects
Authors: M A Schuckit, E Gold, C Risch
Journal: American Journal of Psychiatry (1987)

The authors evaluated changes in serum prolactin levels as a measure of differences in response to ethanol between 30 healthy, drinking, young adult sons of alcoholics and 30 matched control subjects with no family history of psychiatric or substance abuse problems. The control subjects were matched for demographic variables, drug use histories, and alcohol use histories. Each individual was tested on three occasions, receiving, in random order, placebo, 0.75 ml/kg of ethanol, and 1.1 ml/kg of ethanol. Controlling for baseline prolactin measures and hormonal changes after placebo, the authors found that the sons of alcoholics had significantly lower prolactin levels in response to the high-dose ethanol challenge.
Retreatment for relapse following desipramine discontinuation in dysthymia
Authors: R A Friedman, J Mitchell, J H Kocsis
Journal: American Journal of Psychiatry (1995)

It is an accepted yet unproven belief that prior favorable response to an antidepressant medication predicts good response to the same antidepressant during a subsequent depressive episode. The authors studied desipramine retreatment for dysthymic patients who had responded to desipramine during acute and continuation treatment and then subsequently relapsed after discontinuation of desipramine.The subjects were 12 patients who had pure dysthymia or dysthymia with major depression who relapsed while taking placebo during maintenance treatment. Each patient received open desipramine treatment at a dose equal to or greater than that received during the continuation phase.Eleven (91.7%) of the 12 relapsed patients achieved full remission after an average of 4.7 weeks (range = 2-8 weeks, median = 4 weeks) of desipramine retreatment, a significant response rate.Positive response to desipramine strongly predicts favorable response to retreatment for depressive relapse following desipramine discontinuation.
Flow Diversion for the Treatment of Intracranial Aneurysms
Authors: Brian P. Walcott, Christopher J. Stapleton, Omar Choudhri, Aman B. Patel
Journal: JAMA Neurology (2016)

Brain aneurysms have traditionally been treated with surgical clipping or endovascular coiling techniques. With these modalities, many large or complex aneurysms remain difficult to treat. A new option, flow diversion, is now available to treat aneurysms.To summarize the clinical progression of flow diversion technology, from an experimental treatment to a commonly used method to treat large or complex aneurysms.References for this topical review were identified by searches of PubMed and GoogleScholar between January 2000 and January 2016. The search terms aneurysm, flow diverter, stent, pipeline, FRED, SURPASS, SILK, flow diversion, and endovascular were used. Ongoing clinical trials were identified using the same search terms in the clinicaltrial.gov registry. Attention was focused on current indications, rates of complications, and areas of ongoing study in randomized clinical trials.Flow diversion is a treatment approved by the US Food and Drug Administration for brain aneurysms that redirects blood flow away from the aneurysm, thereby promoting growth of a new endothelial lining across the aneurysm opening. Cure rates with this technology are high and complication rates are low.Flow diversion is a disruptive technology that has changed the way many brain aneurysms are treated. It is currently a preferred treatment option for large or giant wide-necked proximal internal carotid artery aneurysms. Ongoing randomized studies will help to more rigorously determine the efficacy of flow diversion.
Growth hormone response to edrophonium in Alzheimer's disease
Authors: O J Thienhaus, F P Zemlan, D Bienenfeld, J T Hartford, H B Bosmann
Journal: American Journal of Psychiatry (1987)

Neuropathologic data from patients with Alzheimer's disease indicate the presence of neurofibrillary tangles in hypothalamic regions associated with regulation of pituitary hormone release. The authors explored the hypothesis that cholinergic projections to hypothalamic nuclei controlling pituitary growth hormone (GH) release degenerate in Alzheimer's disease. Integrity of cholinergic regulation was tested by assaying the GH response to a presynaptic cholinergic challenge. After administration of the choline esterase inhibitor edrophonium, the peak GH response was 14 ng/ml in healthy elderly control subjects and only 2 ng/ml in Alzheimer's patients. The magnitude of GH blunting was correlated with cognitive and functional deficits. Possible implications of these data for enhanced accuracy in the diagnosis of dementia are discussed.
Case 20-1985
Authors: Richard C. Cabot, Robert E. Scully, Eugene J. Mark, Betty U. McNeely, Robert H. Schapiro, David L. Gang
Journal: New England Journal of Medicine (1985)

Presentation of CaseA 39-year-old man was admitted to the hospital because of melena and abdominal pain.He was well until one month earlier, when he began to experience intermittent bouts of pain in the right lower abdominal quadrant; the pain was noncrampy and without radiation, with no clear precipitating cause, and resolved spontaneously in 20 minutes. One week before entry he began to have mild night sweats and fatigue. Three days before admission he passed a tarry stool and noticed the onset of orthostatic dizziness and slight nausea. He was brought to the hospital.The patient grew up on . . .
Lrp4 in astrocytes modulates glutamatergic transmission
Authors: Xiang-Dong Sun, Lei Li, Fang Liu, Zhi-Hui Huang, Jonathan C Bean, Hui-Feng Jiao, Arnab Barik, Seon-Myung Kim, Haitao Wu, Chengyong Shen, Yun Tian, Thiri W Lin, Ryan Bates, Anupama Sathyamurthy, Yong-Jun Chen, Dong-Min Yin, Lei Xiong, Hui-Ping Lin, Jin-Xia Hu, Bao-Ming Li, Tian-Ming Gao, Wen-Cheng Xiong, Lin Mei
Journal: Nature Neuroscience (2016)
Emergence of multidrug resistant Salmonella thyphimurium DT 104 in the Czech Republic
Authors: R Karpíšková, D Benes, D Dedicova
Journal: Eurosurveillance (1999)

The Czech Republic is a country in central Europe with a population of about 10 million inhabitants. Salmonellosis is the most commonly reported infectious intestinal disease. Until 1989 about 10 000 cases were reported each year, and similar numbers of S
EPN-29THE ROLE OF RADIOTHERAPY IN PEDIATRIC EPENDYMOMAS - BEYOND ADJUVANT TREATMENT
Authors: Gonçalo Fernandez, Sofia Nunes, Duarte Salgado, Luisa Mirones, Paula Pereira, Sofia Vinhais, Susana Esteves, Filomena Pereira, Margarida Roldão
Journal: Neuro-Oncology (2016)
Abstract 19616: Regadenoson Administration During Pharmacological Stress Test Causes Prolonged Qtc Interval
Authors: Arsalan Rafiq, Tausif Chughtai, Umair Ashraf, Farbod Raiszadeh, Sherry Megalla, Maryam Afshar, Jonathan N Bella, Gayathri Kamalakkannan
Journal: Circulation (2015)

Background: Post-marketing reports have shown prolongation of QT interval with Regadenoson (Reg). We sought to investigate incidence of corrected QT (QTc) prolongation with Reg and its effect on ventricular arrhythmias in our clinical population. Methods: We conducted a retrospective analysis of 844 consecutive patients who underwent Reg myocardial perfusion imaging. EKG was analyzed for QTc and presence of ventricular ectopy. QTc was measured at baseline, 2 minutes after Reg injection and 3 minutes in recovery. Prolonged QTc interval was defined as &gt;470 milliseconds (ms) in women and &gt;450ms in men. Demographic data, medical history and medications were also obtained from medical records. Results: Mean age was 61 ± 11 years, 53% were females. We noticed statistically significant increase in mean QTc at 2 min (460.2 ± 49) compared to baseline (441.4 ± 41.7) (p &lt;0.0001). QTc interval was also increased at recovery (454.5 ± 42.7) compared to baseline (p &lt;0.001). QTc was prolonged in 231 (27.37%), 327 (38.74%) and 248 (29.38%) at baseline, 2min and recovery respectively. There were no clinically significant ventricular arrhythmias that required intervention in any of our patients. The number of new premature ventricular contractions (PVCs) after Reg injection was not significantly higher when we compared patients who had higher QTc interval at 2min compared to baseline (p=0.3). The number of new PVCs after Reg injection was significantly higher amongst patients whose baseline QTc interval was higher compared to those whose recovery-QTc interval higher (7% vs. 4%, with p=0.03). Conclusion: Qtc interval was prolonged after Reg administration during pharmacological stress testing. Higher baseline QTc and not the post Reg QTc predicted increased PVCs. Caution may be needed in patients undergoing Reg with baseline prolonged QTc.
The Cultivation of Walker Carcinosarcoma 256 &lt;italic&gt;in Vitro&lt;/italic&gt; from Cell Suspensions
Authors: Thomas A. McCoy, Robert E. Neuman
Journal: JNCI Journal of the National Cancer Institute (1956)

The Cultivation of Walker Carcinosarcoma 256 in Vitro from Cell Suspensions Get access Thomas A. McCoy, Thomas A. McCoy Biomedical Division of The Samuel Roberts Noble Foundation, Inc., Ardmore, Okla. Search for other works by this author on: Oxford Academic PubMed Google Scholar Robert E. Neuman Robert E. Neuman Biomedical Division of The Samuel Roberts Noble Foundation, Inc., Ardmore, Okla. Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 16, Issue 5, April 1956, Pages 1221–1229, https://doi.org/10.1093/jnci/16.5.1221 Published: 01 April 1956 Article history Received: 18 October 1955 Published: 01 April 1956
Letter to the editor: Ongoing outbreak of dengue type 1 in the Autonomous Region of Madeira, Portugal
Authors: S K Ramchurn, S S Goorah
Journal: Eurosurveillance (2013)

Preview this article: Letter to the editor: Ongoing outbreak of dengue type 1 in the Autonomous Region of Madeira, Portugal, Page 1 of 1 < Previous page | Next page > /docserver/preview/fulltext/eurosurveillance/18/2/art20351-en-1.gif
Lead Poisoning
Authors: Sarah Ringold
Journal: JAMA (2005)

Lead PoisoningL ead poisoning is the presence of an elevated level of lead in the blood.It is estimated that about 2% of children younger than 6 years in the United States have elevated blood lead levels.Lead enters the blood and other organs primarily through the lungs (from breathing contaminated air) and the digestive tract (from eating contaminated substances).Lead can have damaging effects on any organ in the body, but it is particularly damaging to the central nervous system (the brain and spinal cord) and red blood cells (cells that carry oxygen in the blood).Lead is toxic to both adults and children.It is particularly dangerous for children younger than 6 years because they are still growing and their nervous system is still developing.Even a slightly increased blood lead level may have toxic effects, so it is important to see your doctor immediately if you believe you or your family to be at risk.The May 11, 2005, issue of JAMA includes an article that reports rates of followup testing for children with high blood lead levels in the state of Michigan.
Pattern of onset of bulimic symptoms in anorexia nervosa
Authors: J A Kassett, H E Gwirtsman, W H Kaye, H A Brandt, D C Jimerson
Journal: American Journal of Psychiatry (1988)

Among patients with anorexia nervosa in a research program, the proportion of those who had developed bulimia before anorexia increased between 1976 and 1987. These preliminary results may reflect a new symptom pattern with important clinical and research implications.
LG-33PEDIATRIC INFRATENTORIAL GANGLIOGLIOMA: RESULTS OF A SERIES OF 33 CHILDREN AND LITERATURE REVIEW
Authors: Stephanie Puget, awad Alshehri, kevin Beccaria, Thomas Blauwblomme, Giovanna Paternoster, Timothe De saint Denis, Syril James, Christelle Dufour, Franck Bourdeaut, Pascale Varlet, Christian Sainte Rose, Michel Zerah
Journal: Neuro-Oncology (2016)
Smoking Cessation in Older Patients with Coronary Artery Disease
Authors: D L Hare
Journal: New England Journal of Medicine (1989)

To the Editor: The data from the CASS registry (Nov. 24 issue)1 provide further confirmation of the association between cessation of smoking and improvement in cardiac risk, extending the association to older as well as younger persons with coronary artery disease. However, a number of additional variables were not included in the study that could have contributed to the apparent benefits seen in those who quit smoking, as compared with the continuing smokers. It has been demonstrated prospectively that before they quit smoking, quitters differ from continuing smokers with respect to a number of base-line factors.2 For example, they are… © 1989, Massachusetts Medical Society. All rights reserved.
Abstract 12674: Left Ventricular Myocardial Strain Gradient on a Novel Multi-layer Transthoracic Echocardiography Technique Positively Correlated With Degree of Severe Aortic Stenosis
Authors: Koya Ozawa, Nobusada Funabashi, Hiroyuki Takaoka, Yoshio Kobayashi
Journal: Circulation (2015)

Introduction: A recently developed transthoracic echocardiography (TTE) technique enables detailed myocardial multi-layer analysis of left ventricular (LV) endocardial, epicardial and whole transmural layer strain. Hypothesis: Myocardial strain gradient, defined as endocardial/epicardial strain may influence aortic stenosis (AS) severity. To probe the mechanism behind AS severity we measured myocardial strain gradients in severe AS subjects with preserved LV ejection fraction (LVEF) using a novel, multi-layer speckle tracking TTE technique. Methods: 36 severe AS subjects (19 male, 77±7 years, LVEF &gt;50%, transaortic maximum velocity 4.8±0.6m/s, aortic valve area index (AVAI) 0.45±0.11 cm2/m2) underwent TTE (Vivid E9, GE Healthcare). Apical 4-, 2-, and 3-chamber GLS views and parasternal short axis GCS views at the level of the mitral valve, papillary muscle, and apex were acquired. GLS was defined as all 17 averaged LV segments. GCS was defined as averaged LV segments at the level of the mitral valve, papillary muscle, and apex, respectively. Furthermore strain measurements of whole, endocardial, and epicardial layers were performed. Myocardial strain gradient was defined as: endocardial/epicardial strain. Results: Absolute value of averaged endocardial layer 2D LV GLS was significantly greater than that in the epicardial layer (P&lt;0.001). Absolute values of endocardial layer GCS at all levels were significantly greater than those of the epicardial layer(all P&lt;0.001). The GLS, but not the GCS at any levels, gradient significantly positively correlated with transaortic maximum velocity (R=0.404, P=0.015) and negatively correlated with AVAI (R=-0.463 P=0.005). Conclusions: In severe AS subjects with preserved LVEF, the LV GLS gradient positively correlated with transaortic maximum velocity and negatively correlated with AVAI. Therefore GLS gradients may influence AS severity.