tbuckley/cabot-search huggingface dataset:
U.S. Lawmakers and Politicians Formalize Support for RU 486
Authors: L. Fintor
Journal: JNCI Journal of the National Cancer Institute (1991)

Journal Article U.S. Lawmakers and Politicians Formalize Support for RU 486 Get access Lou Fintor Lou Fintor Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 83, Issue 12, 19 June 1991, Pages 816–817, https://doi.org/10.1093/jnci/83.12.816 Published: 19 June 1991
O6.08 * COMBINED ANALYSIS OF TERT, EGFR AND IDH STATUS DEFINE DISTINCT PROGNOSTIC CLASSES OF GLIOBLASTOMA
Authors: M. Labussiere, B. Boisselier, K. Mokhtari, A. Di Stefano, A. Rahimian, O. Saulnier, R. Paterra, G. Finocchiaro, Y. Marie, M. Sanson
Journal: Neuro-Oncology (2014)

BACKGROUND: The importance of telomerase reverse transcriptase (TERT) in gliomagenesis has been recently strengthened by the frequent occurrence of TERT promoter mutations in glioblastomas. METHODS: We sequenced the TERT promoter mutation in DNA from 395 glioblastomas and analyzed the results with their respective histology, genetic profile (IDH1 mutation, EGFR amplification, CDKN2A homozygous deletion, loss of chromosomes 9 and 10, TP53 mutation), and overall survival (OS). RESULTS: TERT promoter mutations (TERTp-mut) were found in 299/395 glioblastomas (75.7%) and were associated with an older age (median 59.6 for TERTp-mut vs. 53.6 years for TERT promoter wild type (TERTp-wt) p < 0.0001). TERTp-mut was an independent factor of poor prognosis (OS= 13.8 vs. 18.4 months), in both IDH mutated (OS= 13.8 vs. 37.6 months, p= 0.022) and IDH wild type (IDHwt) GBM (OS= 13.7 vs. 17.5 months, p= 0.006). TERTp-mut was associated with IDH-wt and EGFR amplification (EGFR-amp) status. In TERTp-wt group, OS was twice longer in EGFR wt than in EGFR-amp GBM (OS= 26.6 vs. 13.3 months; p= 0.005). In the EGFR-wt group, TERTp-wt patients had a significantly better outcome (OS= 26.3 vs. 12.5 months; p< 0.0001), whereas in the EGFR-amp group, TERTp-mut patients survived longer (OS = 15.8 vs. 13.3 months; p= 0.05). Taken together, the absence of both EGFR-amp and Tertp-mut is associated with longer survival in glioblastoma patients (26.5 months for IDH-wt, 36.7 months for IDH-mut patients). CONCLUSIONS: The analysis of TERT promoter mutations, in combination with EGFR amplification and IDH mutation status, refines the prognostic classification of GBM.
TREATMENT OF HYPERKALEMIA WITH ZS-9, A SELECTIVE NONABSORBED CATION EXCHANGE RESIN, DOES NOT LEAD TO HYPOMAGNESEMIA: RESULTS FROM TWO MULTICENTER, RANDOMIZED, DOUBLE BLIND, PLACEBO-CONTROLLED PHASE 3 TRIALS
Authors: Mohamed A. El-Shahawy, Henrik S. Rasmussen, Philip T. Lavin, Alex Yang, Wajeh Qunibi
Journal: Journal of the American College of Cardiology (2015)
Abstract 4935: microRNA profiling of esophageal squamous cell carcinoma patients from formalin-fixed paraffin-embedded (FFPE) specimens
Authors: Yutaka Shimada, Tomoyuki Okumura, Shin-ichi Sekine, Soshi Osawa, Junya Fukuoka, Kazuhiro Tsukada
Journal: Cancer Research (2011)

Abstract Introduction: microRNA (miRNA) are small non-coding RNAs which target specific mRNA. Recent progression of RNA extraction technology from formalin-fixed paraffin-embedded (FFPE) tissues enables us to access miRNA profiling using world wide stored specimens. Here, we present miRNA profiling of esophageal squamous cell carcinoma (ESCC) patients from FFPE specimens. Method: First, we examined and contrasted the levels of cross-linking caused by formalin and degradation of mRNA and miRNA from daily to yearly time frames. Then, we established the criteria of evaluable RNA from FFPE specimens. The miRNA profiling was obtained from 44 ESCC patients who received operations from 1991 to 2009 using 3D-Gene human miRNA chip (Toray) which contains 904 has-miRNAs. The approval number from Toyama University institutional review board was #19-67. Results: Out of 44 paired samples, 24 pairs (54.5%) were determined evaluable with our criteria. We found that 39 miRNAs (including miR-21, and miR-25) were significantly up-regulated and that 24 miRNAs (including miR-145) were down-regulated in ESCC in comparison to normal esophageal tissue. Of these, miR-15b, miR-200c and miR761 were identified as prognostic factors of ESCC patients. Furthermore, we found 22 miRNAs that have association with the hematogenic recurrence and 9 miRNAs (including miR-103) have association with lymph node metastasis. Conclusion: We have discovered miRNAs that are associated with prognosis, hematogenic recurrence and lymph node metastasis in ESCC patients. miRNA profiling using FFPE specimens is a useful and promising method of evaluation of world wide stored specimens that accompany many valuable clinical data. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 102nd Annual Meeting of the American Association for Cancer Research; 2011 Apr 2-6; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2011;71(8 Suppl):Abstract nr 4935. doi:10.1158/1538-7445.AM2011-4935
Prospective Observational Study on the Evaluation of Everolimus Adverse Events (Aes) in Metastatic Renal Cell Carcinoma (Mrcc) After First-Line Anti-Vegf Therapy. the French Afinite Study
Authors: F. Joly Lobbedez, J. Eymard, L. Albiges Sauvin, T. Nguyen, A. Guillot, F. Rolland, D. Spaeth, B. Laguerre, P. Colin, T. Lebret, K. Slimane, N. Kelkouli, A. Ravaud
Journal: Annals of Oncology (2014)
The Thrombogenic Effect of Anticancer Drug Therapy in Women with Stage II Breast Cancer
Authors: M N Levine, M Gent, J Hirsh, A Arnold, M D Goodyear, W Hryniuk, S De Pauw
Journal: New England Journal of Medicine (1988)

Thromboembolic disease has long been recognized as a complication of cancer. Recent reports have suggested that drugs used in the treatment of cancer, including chemotherapeutic agents and hormones, may contribute to this risk, but it has not been possible to separate the effect of these drugs from that of the cancer. We performed a randomized trial comparing 12 weeks of chemohormonal therapy (using cyclophosphamide, methotrexate, fluorouracil, vincristine, prednisone, doxorubicin, and tamoxifen) with 36 weeks of chemotherapy (using cyclophosphamide, methotrexate, fluorouracil, vincristine, and prednisone) in patients with Stage II breast cancer. Among 205 patients randomly assigned to treatment, there were 14 episodes of thrombosis (6.8 percent). These 14 episodes occurred during 979 patient-months of chemotherapy; by comparison, there were no events during 2413 patient-months without therapy. During the first 12 weeks of the study, five patients in the 12-week group and four patients in the 36-week group had thrombosis. During the subsequent 24 weeks, when only patients in the 36-week group were still receiving chemotherapy, there was no thrombosis in the 12-week group, but there were five additional events in the 36-week group (P = 0.03). These findings suggest that chemotherapy contributes to thrombosis in patients with breast cancer.
PRE-OPERATIVE CHEMOTHERAPY AS A NEW STRATEGY OF TREATMENT FOR LOW GRADE GLIOMAS IN ELOQUENT AREAS
Authors: R. Ruda, L. Bello, A. Castellano, L. Bertero, E. Trevisan, M. Riva, A. Falini, R. Soffietti
Journal: Neuro-Oncology (2014)

BACKGROUND: (blind field). METHODS: Patients with LGG after biopsy or partial resection at a previous surgery, who progressed with increasing seizures and/or radiologically, received 1 week on/1 week off temozolomide to a maximum of 12 cycles. Response on MRI-FLAIR images was evaluated every 3 months based on RANO and volumetric criteria. Changes on diffusion tensor imaging (DTI) were assessed by histogram analysis and Functional Diffusion Maps and compared with RANO and volumetric criteria, and response of seizures. RESULTS: 24 patients with an histological diagnosis of LGG according to WHO 2007 were enrolled from 2008 to 2013: 19/24 males, median age 32 years (range 23-56) and median KPS 90. Reasons for chemotherapy were either a large residual tumor in 15/24 (seizures in 13/15) or tumor progression in 9/24 (seizures in 3/9). Nineteen of 24 patients are evaluable so far for response, while 5 patients are still under treatment. Median number of cycles was 6 (range 4-12). Best response according to RANO was: MR in 3/19 (16%), SD in 14/19 (74%) and PD in 2/19 (10%). Among patients with response or stable disease according to RANO, tumor volume reduction on FLAIR images ranged between 4.3% and 42.7% (median: 26.6%). In all patients significant changes in diffusion patterns, suggestive of a reduced tumor infiltration, were observed after 3 cycles (p < 0.05) and became more significant (p < 0.01) after 6 cycles. Twelve out of 15 patients had a significant reduction of seizure frequency concurrent with significant changes on DTI despite a volumetric stability. Seventeen out of 19 patients underwent reoperation (most after 6 cycles of temozolomide): overall a near-total resection (≥95%) was achieved in 9/19 (47%) patients of the whole series. In 4 patients total resection was confirmed by the absence of IDH1 mutated cells in tumor margins. CONCLUSIONS: Preoperative chemotherapy in patients with LGG in “eloquent” areas can allow a total near-total resection at reoperation in a significant subset of patients. DTI changes may be an early signature for response and correlate with seizure response better than conventional MRI. Moreover, DTI could improve the evaluation of feasibility and timing of reoperation. SECONDARY CATEGORY: n/a.
Defect in Pyridine Nucleotide Dependent Superoxide Production by a Particulate Fraction from the Granulocytes of Patients with Chronic Granulomatous Disease
Authors: John T. Curnutte, Ruby S. Kipnes, Bernard M. Babior
Journal: New England Journal of Medicine (1975)

Particulate fractions from normal human granulocytes preactivated with opsonized zymosan were found to catalyze superoxide production in the presence of reduced pyridine nucleotides. Similar preparations from three patients with X-linked chronic granulomatous disease produced no detectable superoxide. The failure to produce superoxide was not due to an inhibitor, since cell-free preparations from the patients' granulocytes had no effect on superoxide production by normal particles. Particles from the mothers of two of the patients produced superoxide at diminished rates; superoxide production by particles from the third mother was normal. These findings suggest that chronic granulomatous disease represents either a defect in a pyridine nucleotide-dependent superoxide-forming oxidase or a lesion in the apparatus responsible for activating the oxidase.
Stat Bite Colorectal Cancer Incidence:*Response to President Reagan's Cancer
Authors: A. Potosky, M. Brown
Journal: JNCI Journal of the National Cancer Institute (1991)

Stat Bite Colorectal Cancer Incidence: * Response to President Reagan's Cancer Arnold Potosky, Arnold Potosky Search for other works by this author on: Oxford Academic PubMed Google Scholar Martin Brown, Ph.D. Martin Brown, Ph.D. Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 83, Issue 6, 20 March 1991, Page 387, https://doi.org/10.1093/jnci/83.6.387 Published: 20 March 1991
Remission of Progressive Multifocal Leukoencephalopathy Following Splenectomy and Antiretroviral Therapy in a Patient with HIV Infection
Authors: Christopher Power, Avi Nath, Fred Y. Aoki, Marc Del Bigio
Journal: New England Journal of Medicine (1997)

To the Editor: Progressive multifocal leukoencephalopathy caused by JC papovavirus infection of glial cells is an increasingly frequent complication of human immunodeficiency virus (HIV) type 1 inf...
432 TRANSFER OF HEPATITIS B SURFACE MARKERS AND HBVDNA FROM HEPATITIS B SURFACE ANTIGEN POSITIVE MOTHERS TO THEIR OFFSPRING
Authors: J. Wang, Y. Zhao, Y. Feng, H. Liu, H. Song, N. Yuan, D. Du, W. Feng, J. Liu, Y. Yang, Y. He, T. Chen
Journal: Journal of Hepatology (2013)
<i>Cladosporium macrocarpum</i>brain abscess after endoscopic ultrasound-guided celiac plexus block
Authors: A. Lalueza, F. López-Medrano, A. del Palacio, A. Alhambra, E. Álvarez, A. Ramos, A. Pérez, M. Lizasoain, Y. Meije, A. García-Reyne, J. Aguado
Journal: Endoscopy (2011)

A 45-year-old man presented with a 24-hour history of holocranial headache and right-side deviation of the oral commissure. He denied fever and other neurological symptoms. He had undergone endoscopic ultrasound (EUS)-guided celiac plexus neurolysis (CPN) 3 weeks before for the management of refractary epigastric pain caused by alcoholic chronic pancreatitis.
Case 40-2001
Authors: Cliff A. Megerian, Tessa A. Hadlock
Journal: New England Journal of Medicine (2001)

Presentation of CaseAn eight-year-old boy was admitted to the Massachusetts Eye and Ear Infirmary because of fever, headache, vertigo, and vomiting.The child had been well until two days before admission, when he became dizzy and nauseated immediately after being struck in the left ear by a baseball. He did not lose consciousness or have tinnitus, impairment of hearing, otorrhea, or rhinorrhea. An evaluation performed elsewhere showed erythema of the pinna and an unsteady gait. A cranial computed tomographic (CT) study was said to show no abnormality. Promethazine was prescribed, and the boy was sent home. On the next . . .
A Healthier White House Without Smoke
Authors: J. Mathews
Journal: JNCI Journal of the National Cancer Institute (1993)

Journal Article A Healthier White House Without Smoke Get access James Mathews James Mathews Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 85, Issue 6, 17 March 1993, Page 430, https://doi.org/10.1093/jnci/85.6.430 Published: 17 March 1993
Blackpool is OK
Authors: B. Dixon
Journal: BMJ (1996)

One feature of this year's silly season has been a spate of silly articles attacking Blackpool. Allegations include its descent from stylish vulgarity into seediness and mess, and the decline into decrepitude of once great attractions such as the tower. Well, I have good news for Blackpool's tourist department. Visiting its resort is beneficial to health.

“Blackpool is valuable for the treatment of tubercular adenitis and adenoids; early phthisis; cardiac disease, where there is enough muscle power; anaemia and convalescence; neurasthenia, and mental overstrain,” writes Dr Edgar Hawkins. One of very few places he advises doctors to send their patients to, not only in summer but …
PRE-PROCEDURAL COMPUTED TOMOGRAPHIC EVALUATION TO PREDICT FAILURE OR COMPLICATIONS OF ENDOVASCULAR THERAPY FOR ILIAC ARTERY STENOSIS AND ITS OUTCOMES
Authors: Sung-Jin Hong, Young-Guk Ko, Dong-Ho Shin, Jung-Sun Kim, Byeong-Keuk Kim, Donghoon Choi, Myeong-Ki Hong, Yang Soo Jang
Journal: Journal of the American College of Cardiology (2015)
Abstract 88: Promoter hypermethylation leads to loss of Wnt7a in NSCLC
Authors: Meredith A. Tennis, Michelle VanScoyk, Scott Freeman, Robert Winn
Journal: Cancer Research (2011)

Abstract The Wnt signaling pathway is critical to normal development but the involvement of the pathway in lung tumorigenesis has not been clearly established. Wnt7a, with its receptor Fzd9, is required for maintenance of epithelial differentiation and inhibits transformed growth. Wnt7a has been shown to be frequently lost in NSCLC cell lines and tumors. We demonstrate that loss of Wnt7a in a non-transformed lung epithelial cell line leads to increased proliferation. Using pyrosequencing, 58 of 81 (72%) of NSCLC tumors we tested had higher methylation in the Wnt7a promoter region compared to adjacent normal lung tissue. We also tested 10 pairs of human NSCLC tumor and normal adjacent lung samples with known loss of expression of Wnt7a in the tumor and 6 (60%) had increased methylation of the Wnt7a promoter region in the tumors. Two NSCLC cell lines demonstrated to have methylated Wnt7a and loss of Wnt7a expression, H157 and H1299, were used to investigate methylation of the Wnt7a promoter. Treatment of these cell lines with 5-aza-2deoxycytidine resulted in increased expression of Wnt7a and increased downstream activity of known targets of Wnt7a-Fzd9 signaling. Methylation of a Wnt7a promoter luciferase resulted in decreased activity of the luciferase compared to an untreated Wnt7a luciferase. NNK is a tobacco carcinogen known to attenuate DNMT1 degradation, leading to increased promoter methylation. Treatment of a non-transformed lung epithelial cell line with NNK resulted in decreased expression of Wnt7a and increased clonogenicity. Together, these results indicate that Wnt7a is frequently lost by methylation in NSCLC and that methylation of Wnt7a leads to decreased expression. Wnt7a could be methylated by exposure to tobacco carcinogens, leading to loss of expression and increased transformed lung cell growth. The clinical use of demethylating agents could restore Wnt7a activity, helping to decrease growth of NSCLC. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 102nd Annual Meeting of the American Association for Cancer Research; 2011 Apr 2-6; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2011;71(8 Suppl):Abstract nr 88. doi:10.1158/1538-7445.AM2011-88
MICRORNAS 206, 155-5P, AND 374A-5P ARE KEY REGULATORS OF INFLAMMATION AND RELATE TO CIRCULATING C-REACTIVE PROTEIN LEVELS IN PATIENTS WITH ATRIAL FIBRILLATION: DATA FROM THE MIRHYTHM STUDY
Authors: Suvasini Lakshmanan, Honghuang Lin, Kahraman Tanriverdi, Esa Nada, Senthil Sivalingam, Kevin Donahue, John Keaney, Emelia Benjamin, Kevin Floyd, Lawrence Rosenthal, Jane Freedman, David McManus
Journal: Journal of the American College of Cardiology (2016)
Comparison of Outcomes Between Responders and Nonresponders to First-Line Paclitaxel/Carboplatin (P/C) Doublet Chemotherapy in Patients (Pts) with Advanced Non-Small Cell Lung Cancer (Nsclc)
Authors: V. Hirsh, C. Langer, F. Ju-Lin, Y. Wan, I. Okamoto, S. Whiting, T.J. Ong, M. Botteman
Journal: Annals of Oncology (2014)
A10.02 Deficiency in IL-1 receptor type 2 aggravates K/BXN serum transfer-induced arthritis in mice, but has no effect in endotoxemia
Authors: P Martin, G Palmer, E Rodriguez, CA Seemayer, D Talabot-Ayer, C Gabay
Journal: Annals of the Rheumatic Diseases (2016)

<h3>Introduction</h3> The biological activity of interleukin (IL)-1 is tightly regulated by a specific receptor antagonist (IL-1Ra) and the decoy receptor IL-1R2. The role of IL-1Ra has been well demonstrated in IL-1Ra deficient mice. In contrast, the role of endogenous IL-1R2 remains widely unknown. <h3>Methods</h3> We generated IL-1R2 deficient mice in a C57BL/6 background and investigated the role of IL-1R2 in both lipopolysaccharide (LPS)-induced lethality by injecting 10 mg/kg <i>E. coli</i> LPS intraperitoneally (i.p.), and in systemic inflammatory responses induced by i.p. injections of 10 µg/kg IL-1β. Lethality was monitored daily and serum cytokine levels were measured at different time points by ELISA, respectively. Arthritis was induced by injecting i.p. 1.5 mg purified arthritogenic IgGs purified from K/BxN serum. Arthritis severity was assessed by clinical and histological scoring. Tissue mRNA levels of cytokines were measured by real-time PCR. <h3>Results</h3> IL-1R2 deficient mice bred normally and exhibited a grossly normal phenotype. IL-1R2 was selectively expressed by wild-type (WT), but not IL-1R2 deficient, neutrophils. The number of immune cells in bone marrow, spleen and peripheral blood was similar in IL-1R2 deficient and WT mice. The phagocytic function and oxidative burst of IL-1R2 deficient neutrophils were normal. The rate of LPS-induced mortality and the level of inflammatory responses to IL-1b were similar in IL-1R2 deficient mice and their WT littermates. In contrast, IL-1R2 deficiency was associated with aggravated arthritis severity. Levels of IL-6, IL-1β, CXCL-1 and CXCL-2 mRNA were significantly increased in ankles of IL-1R2 deficient mice. Immunohistochemical analyses indicated that IL-1R2 is mainly expressed by infiltrating neutrophils. <h3>Conclusions</h3> These data show that the decoy receptor IL-1R2 plays an important role during K/BxN serum transfer-induced inflammatory arthritis and suggest that neutrophils exert anti-inflammatory activities in arthritis by expressing IL-1R2. However, in contrast to IL-1Ra, IL-1R2 is not essential for normal homeostasis and systemic responses to LPS and acute IL-1 administration.
Response to Letters Regarding Article, “Arrhythmic Mitral Valve Prolapse and Sudden Cardiac Death”
Authors: Cristina Basso, Martina Perazzolo Marra, Stefania Rizzo, Manuel De Lazzari, Benedetta Giorgi, Alberto Cipriani, Anna Chiara Frigo, Ilaria Rigato, Federico Migliore, Kalliopi Pilichou, Emanuele Bertaglia, Luisa Cacciavillani, Barbara Bauce, Domenico Corrado, Gaetano Thiene, Sabino Iliceto
Journal: Circulation (2016)
ATTENUATED RESPONSE OF LIPID PLAQUE TO CHOLESTEROL LOWERING THERAPY IN DIABETIC PATIENT: AN OPTICAL COHERENCE TOMOGRAPHY STUDY
Authors: Sining Hu, Haibo Jia, Jingbo Hou, Xing Lei, JinWei Tian, Koji Kato, Taishi Yonetsu, Rocco Vergallo, Farhad Abtahian, zhigang han, Lingbo Meng, Huai Yu, Shaosong Zhang, Bo Yu, Ik-Kyung Jang
Journal: Journal of the American College of Cardiology (2013)
PWE-279 The hepatic effects of a high fructose vs a high glucose diet in healthy overweight men: Abstract PWE-279 Table 1
Authors: R D Johnston, M C Stephenson, H Crossland, S M Cordon, M A Taylor, G P Aithal, I A Macdonald
Journal: Gut (2012)

<h3>Introduction</h3> A high intake of fructose has been implicated in NAFLD aetiology. As the majority of dietary fructose originates from sucrose it remains uncertain if these observations are fructose-specific. Infrequent and inconsistent differences in hepatic metabolism have been shown with a high intake of fructose or glucose, the constituents of sucrose.<sup>1 2</sup> There is no prior comparative data in healthy overweight men, and none in the isoenergetic state. <h3>Methods</h3> 32 healthy, centrally overweight males were randomised to two periods each of 2 weeks of either a high fructose or glucose intake in a non-crossover fashion. Isoenergetic status was maintained by providing foodstuffs during the first period, followed by a 6-week washout and then a second period of <i>ad libitum</i> overfeeding. The sugars contributed 25% of predicted total energy requirements, and were consumed 4 times a day dissolved in water. The primary outcome was hepatic triglyceride content (<sup>1</sup>H MRS), with further assessments of calf lipid (<sup>1</sup>H MRS), deuterated glucose hyperinsulinaemic euglycaemic clamps, and indirect calorimetry. Outcomes assessed by Student t test. <h3>Results</h3> The groups were well matched at study entry. Overall the subjects9 mean age was 34 years, BMI 29.4 kg/m<sup>2</sup> and daily dose of sugars was 217 g. The changes in the primary measures are shown in the Abstract PWE-279 table 1 below. There were no changes during the energy balanced period. With energy and monosaccharide overfeeding weight, serum triglycerides, liver lipid and biochemistry increased significantly, but to a similar extent in both groups. Further to this the groups did not differ in terms of satiety, whole body oxidative profile, hepatic insulin resistance, calf lipid, or renal function. <h3>Conclusion</h3> There were no differences between a high fructose and glucose diet in relation to hepatic lipids or biochemistry. The changes during the overfeeding period were strongly associated with changes in weight, reinforcing the interpretation that these were an energy, as opposed to a nutrient, specific effect. <h3>Clinical trial registration number</h3> NCT01050140. <h3>Competing interests</h3> None declared. <h3>References</h3> 1. <b>Stanhope KL</b>, Schwarz JM, Keim NL, <i>et al.</i> Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans. <i>J Clin Invest</i> 2009;<b>119</b>:1322–34. 2. <b>Ngo Sock ET</b>, Lê KA, Ith M, <i>et al.</i> Effects of a short-term overfeeding with fructose or glucose in healthy young males. <i>Br J Nutr</i> 2010;<b>103</b>:939–43.