Behavioral Counseling and Pharmacotherapy Interventions for Tobacco Cessation in Pregnant Women
Authors: Alain Braillon, Susan Bewley
Journal: Annals of Internal Medicine (2016)

Letters3 May 2016Behavioral Counseling and Pharmacotherapy Interventions for Tobacco Cessation in Pregnant WomenAlain Braillon, MD, PhD and Susan Bewley, MDAlain Braillon, MD, PhDFrom University Hospital, Amiens, France, and Kings College London, London, United Kingdom.Search for more papers by this author and Susan Bewley, MDFrom University Hospital, Amiens, France, and Kings College London, London, United Kingdom.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/L15-0625 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:With its “review of reviews” for the U.S. Preventive Services Task Force, Patnode and colleagues (1) failed to critically analyze a recent negative trial (2) and missed a major well-designed trial on nicotine replacement therapy (NRT) (3).The authors included a trial of low-dose nicotine patches alone (16 mg of nicotine delivered over 16 hours) that unsurprisingly failed to decrease withdrawal symptoms and craving versus placebo (2), because pregnant women are highly dependent on nicotine due to increased metabolism (4).Combining patches with faster-acting forms of NRT as a “belt-and-braces” strategy works substantially better than patches alone, ...References1. Patnode CD, Henderson JT, Thompson JH, Senger CA, Fortmann SP, Whitlock EP. Behavioral counseling and pharmacotherapy interventions for tobacco cessation in adults, including pregnant women: a review of reviews for the U.S. Preventive Services Task Force. Ann Intern Med. 2015;163:608-21. [PMID: 26389650]. doi:10.7326/M15-0171 LinkGoogle Scholar2. Brose LS, McEwen A, West R. Association between nicotine replacement therapy use in pregnancy and smoking cessation. Drug Alcohol Depend. 2013;132:660-4. [PMID: 23680076] doi:10.1016/j.drugalcdep.2013.04.017 CrossrefMedlineGoogle Scholar3. Berlin I, Grangé G, Jacob N, Tanguy ML. Nicotine patches in pregnant smokers: randomised, placebo controlled, multicentre trial of efficacy. BMJ. 2014;348:g1622. [PMID: 24627552] doi:10.1136/bmj.g1622 CrossrefMedlineGoogle Scholar4. Koren G, Blanchette P, Lubetzky A, Kramer M. Hair nicotine:cotinine metabolic ratio in pregnant women: a new method to study metabolism in late pregnancy. Ther Drug Monit. 2008;30:246-8. [PMID: 18367989] doi:10.1097/FTD.0b013e318167d05b CrossrefMedlineGoogle Scholar5. Benowitz NL, Hukkanen J, Jacob P. Nicotine chemistry, metabolism, kinetics and biomarkers. Handb Exp Pharmacol. 2009:29-60. [PMID: 19184645] doi:10.1007/978-3-540-69248-5_2 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From University Hospital, Amiens, France, and Kings College London, London, United Kingdom.Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L15-0625. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoBehavioral Counseling and Pharmacotherapy Interventions for Tobacco Cessation in Adults, Including Pregnant Women: A Review of Reviews for the U.S. Preventive Services Task Force Carrie D. Patnode , Jillian T. Henderson , Jamie H. Thompson , Caitlyn A. Senger , Stephen P. Fortmann , and Evelyn P. Whitlock Behavioral Counseling and Pharmacotherapy Interventions for Tobacco Cessation in Pregnant Women Jillian T. Henderson , Carrie D. Patnode , and Stephen P. Fortmann Metrics Cited byTeaching midwives to poke with needles on non-existing meridiansRaise the Bar to Help Pregnant Smokers, Rather Than Lower ItSmoking cessation treatment in substance use disorder treatment settings: an emergency too 3 May 2016Volume 164, Issue 9Page: 637KeywordsAttentionBlood plasmaDisclosureNicotineNicotine replacement therapyOdds ratioPharmacokineticsPharmacologyPregnancyToxicology ePublished: 3 May 2016 Issue Published: 3 May 2016 Copyright & PermissionsCopyright © 2016 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...