SOME SPECIFIC ANTIMALARIAL DRUGS
Authors: P. W. C.
Journal: Annals of Internal Medicine (1948)

Editorial1 October 1948SOME SPECIFIC ANTIMALARIAL DRUGSP. W. C.P. W. C.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-29-4-746 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlthough the drugs which have been in general use are, in most cases, potent in terminating acute attacks of malaria, there are important limitations to their effectiveness and some untoward results attending their administration. Even before the War attempts had been initiated to find more satisfactory specifics. With the advent of the War, the necessity of maintaining armed forces in areas in which malaria is highly endemic as well as the loss of the Dutch East Indies, the only source of quinine in significant quantities, made the problem urgent and acute. Systematic attempts to produce and test new preparations were...1 SINTONSMITHPOTTINGER JASD: Studies in malaria with special reference to treatment. Part XII. Further researches into the treatment of chronic benign tertian malaria with plasmoquine and quinine, Indian Jr. Med. Research, 1930, xvii, 793-814. Google Scholar2 MOST H: Combined quinine-plasmochin treatment of vivax malaria: effect on relapse rate, Am. Jr. Med. Sci., 1946, ccxii, 550-560. CrossrefGoogle Scholar3 BERLINER RW: Studies on the chemotherapy of the human malarias. VII. The antimalarial activity of pamaquine, Jr. Clin. Invest., 1948, xxvii, supplementary number, May, part 2, 108-113. CrossrefGoogle Scholar4 JAMESNICOLSHUTE SPWDPG: On prevention of malaria with plasmoquine, Lancet, 1931, ii, 341-342. CrossrefGoogle Scholar5 JONES R: A study of the prophylactic effectiveness of several 8-aminoquinolines in sporozoite-induced vivax malaria (Chesson strain), Jr. Clin. Invest., 1948, xxvii, supplementary number, May, part 2, 6-11. CrossrefGoogle Scholar6 TAGGERT JV: Studies on the chemotherapy of the human malarias. V. The antimalarial activity of quinacrine, Ibid., 93-97. Google Scholar7 ALVING AS: The clinical trial of 18 analogues of pamaquin [sic] (plasmochin) [sic] in vivax malaria (Chesson strain), Ibid., 34-45. Google Scholar8 ALVING AS: Pentaquine (SN-13,276), a therapeutic agent effective in reducing the relapse rate in vivax malaria, Ibid., 25-33. Google Scholar9 BERLINER RW: Studies on the chemotherapy of the human malarias. VI. The physiological disposition, antimalarial activity, and toxicity of several derivatives of 4-aminoquinoline, Ibid., 98-107. Google Scholar10 MOST H: Chloroquine for treatment of acute attacks of vivax malaria, Jr. Am. Med. Assoc., 1946, cxxxi, 963-967. CrossrefGoogle Scholar11 LOEB RF: Activity of a new antimalarial agent, chloroquine (SN 7618) (Approved statement), Jr. Am. Med. Assoc., 1946, cxxx, 1069-1070. CrossrefGoogle Scholar12 MAEGRAITH BG: Paludrine in the treatment of malaria, Brit. Med. Jr., 1946, i, 903-905. CrossrefGoogle Scholar13 JONES R: The therapeutic effectiveness of large doses of paludrine in acute attacks of sporozoite-induced vivax malaria (Chesson strain), Jr. Clin. Invest., 1948, xxvii, supplementary number, May, part 2, 51-55. CrossrefGoogle Scholar14 FAIRLEY NH: Researches on paludrine (N. 4888) in Australia, Med. Jr. Australia, 1946, i, 234-236. Google Scholar15 EARLE DP: Studies on the chemotherapy of the human malarias. X. The suppressive antimalarial effect of paludrine, Jr. Clin. Invest., 1948, xxvii, supplementary number, May, part 2, 130-133. CrossrefGoogle Scholar16 CRAIGE B: Clinical standardization of pamaquin [sic] (plasmochin) [sic] in mosquito-induced vivax malaria, Chesson strain, Am. Jr. Trop. Med., 1947, xxvii, 309-315. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: P. W. C. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 October 1948Volume 29, Issue 4 Page: 746-751 Keywords Antimalarials Armed forces Drug administration Drugs Malaria Quinine ePublished: 1 December 2008 Issue Published: 1 October 1948 PDF downloadLoading ...