Rheumatoid Arthritis
Authors: Tom W.J. Huizinga, Theodore Pincus
Journal: Annals of Internal Medicine (2010)

In the Clinic6 July 2010Rheumatoid ArthritisBarbara Turner, MD, MSED, Sankey Williams, MD, Darren Taichman, MD, PhD, Tom W.J. Huizinga, MD, PhD, and Theodore Pincus, MDBarbara Turner, MD, MSEDSearch for more papers by this author, Sankey Williams, MDSearch for more papers by this author, Darren Taichman, MD, PhDSearch for more papers by this author, Tom W.J. Huizinga, MD, PhDSearch for more papers by this author, and Theodore Pincus, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-153-1-201007060-01001 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Editor's Note: This issue of In the Clinic has been updated.Rheumatoid arthritis (RA) is a chronic, systemic inflammatory disease affecting approximately 0.5% of the population. Rheumatoid arthritis is more common in women and may occur at any age, with peak incidence at ages 50 to 60 years. The most prominent feature is symmetrical joint swelling of the feet, hands, and knees, although any joint (and some internal organs) may be affected. Rheumatoid arthritis is a clinical syndrome encompassing several disease subsets, each involving inflammatory cascades that generally lead to joint and organ damage if left untreated. Although laboratory test ...References1. Van Nies JAB, de Jong Z, Van der Helm-van Mil AHM, et al. Improved treatment strategies reduce the increased mortality risk in early RA patients. Rheumatology. In press. Google Scholar2. Aletaha D, Neogi T, Silman A, et al. The 2010 American College of Rheumatology/European League Against Rheumatism classification criteria for rheumatoid arthritis. Arthritis Rheum. 2010. [Forthcoming]. Google Scholar3. Aletaha D, Neogi T, Silman A, et al. 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