tbuckley/cabot-search huggingface dataset:
Modes of administration of morphine in cancer pain
Authors: V L Crosby, R Corcoran
Journal: BMJ (1996)

women using hormone replacement therapy for up to five years but was not significantly increased in women using it for longer.5Neither of these obser- vations is consistent with a causal relation between sex steroid hormones and cancer, such as that so clearly shown between unopposed oestrogens and endometrial cancer.Price and Little also com- pletely ignore a recent population based case- control study that showed no increase in the risk of breast cancer even when hormone replacement therapy was taken for 20 years and more.6While relying uncritically on the report on use of hormone replacement therapy and breast can- cer from the nurses' health study, the authors perfunctorily dismiss the finding from the same cohort of a 50% reduction in the risk of myocar- dial infarction among women using the therapy.We recognise that epidemiology has provided no easy answer to the question of whether use of hormone replacement therapy has an effect on the risk of breast cancer, but we object to the promulgation of any attitude towards hormone replacement therapy, whether positive or nega- tive, that is based on prejudice and a personal agenda.Making an announcement of a new organisation is no excuse for such abuse of the literature.Sadly, it is all too easy for those with no clinical responsibility for hormone replace- ment therapy to present a distorted view, to the detriment of women seeking a balanced assessment of the benefits and risks.
Genetic Variations in Calicheamicin Pathway Genes Are Predictors of Gemtuzumab Ozogamicin Response in AML Patients: Results from COG-AAML0531 Study
Authors: Jatinder K Lamba, Lata Chauhan, Richard Aplenc, Maggie Skrypek, Jessica Pollard, Todd A. Alonzo, Y-C Wang, Irwin D. Bernstein, Alan S. Gamis, Soheil Meshinchi
Journal: Blood (2015)
GDE2 is essential for neuronal survival in the postnatal mammalian spinal cord
Authors: Clinton Cave, Sungjin Park, Marianeli Rodriguez, Mai Nakamura, Ahmet Hoke, Mikhail Pletnikov, Shanthini Sockanathan
Journal: Molecular Neurodegeneration (2017)

Glycerophosphodiester phosphodiesterase 2 (GDE2) is a six-transmembrane protein that cleaves glycosylphosphatidylinositol (GPI) anchors to regulate GPI-anchored protein activity at the cell surface. In the developing spinal cord, GDE2 utilizes its enzymatic function to regulate the production of specific classes of motor neurons and interneurons; however, GDE2's roles beyond embryonic neurogenesis have yet to be defined. Using a panel of histological, immunohistochemical, electrophysiological, behavioral, and biochemistry techniques, we characterized the postnatal Gde2 −/− mouse for evidence of degenerative neuropathology. A conditional deletion of Gde2 was used to study the temporal requirements for GDE2 in neuronal survival. Biochemical approaches identified deficits in the processing of GPI-anchored GDE2 substrates in the SOD1 G93A mouse model of familial Amyotrophic Lateral Sclerosis that shows robust motor neuron degeneration. Here we show that GDE2 expression continues postnatally, and adult mice lacking GDE2 exhibit a slow, progressive neuronal degeneration with pathologies similar to human neurodegenerative disease. Early phenotypes include vacuolization, microgliosis, cytoskeletal accumulation, and lipofuscin deposition followed by astrogliosis and cell death. Remaining motor neurons exhibit peripheral motor unit restructuring causing behavioral motor deficits. Genetic ablation of GDE2 after embryonic neurogenesis is complete still elicits degenerative pathology, signifying that GDE2's requirement for neuronal survival is distinct from its involvement in neuronal differentiation. Unbiased screens identify impaired processing of Glypican 4 and 6 in Gde2 null animals, and Glypican release is markedly reduced in SOD1 G93A mice. This study identifies a novel function for GDE2 in neuronal survival and implicates deregulated GPI-anchored protein activity in pathways mediating neurodegeneration. These findings provide new molecular insight for neuropathologies found in multiple disease settings, and raise the possibility of GDE2 hypofunctionality as a component of neurodegenerative disease.
Intensive Treatment in Elderly AML Patients Induce Prolonged Survival and Disease Remission If Early Mortality Is Prevented: The Case Record of the San Raffaele Scientific Institute
Authors: Massimo Bernardi, Matteo Carrabba, Michela Tassara, Carlo Messina, Alessandro Crotta, Elisa Sala, Alessandro Vignati, Elena Guggiari, Raffaella Greco, Luca vago, Bernhard Gentner, Simona Piemontese, Andrea Assanelli, Jacopo Peccatori, Consuelo Corti, Fabio Ciceri
Journal: Blood (2011)
A Cross-Sectional Analysis of the Relationship Between Hormone Replacement Therapy and Coronary Artery Calcification
Authors: Amy M. Gallagher, Enrique F. Schisterman, Noel Bairey Merz, Howard C. Lewin, Sean W. Hayes, John D. Friedman, Romalisa S. Miranda, Arlene Ledesma, Daniel S. Berman
Journal: Circulation (2001)

P24 

Background: There is evidence that estrogen affects the vascular wall, independent of modifications to plasma lipoproteins, by accelerating reendothelialization of damaged blood vessels and by inhibiting smooth muscle cell proliferation. Therefore, we intended to investigate the relationship between hormone replacement therapy (HRT) use and prevalence of coronary calcium (CC) in postmenopausal women. Methods: Cardiac electron beam computed tomography (EBCT) was performed on 793 postmenopausal women participating in the Cedars-Sinai Cardiovascular Observational Study. At the time of their EBCT, 509 women were receiving HRT and 284 were not receiving HRT. The total coronary calcium score was determined using the Agatston method. A self-report of HRT use was assessed in all participants, as well as measurements of other known cardiovascular risk factors. Results: Independent sample t-tests identified the means of the following variables as significantly different between the two groups of women: age, LDL, HDL, and BMI. Self reports of hypertension, smoking, exercise and diet were similar between the two groups. Analysis of variance, controlling for confounders, showed a significant difference (p<.001) between the marginal means (MM) of the two HRT groups for total coronary calcium score, total number of calcified lesions, and total volume of calcium. The MM total CC score was 96.40 (±256.39) for HRT users and 150.97 (±362.54) for non-users. The MM number of lesions for users was 2.16 (±3.37) and 3.36 (±4.75) for non-users. The MM volume of calcium for users was 0.078 (±0.20) and 0.122 (±0.29) for non-users. Conclusions: Total coronary calcium score, total lesions, and total volume were found to be significantly lower in postmenopausal women receiving HRT than for those not receiving HRT. These findings support the hypothesis that hormone replacement therapy is associated with a lower prevalence of coronary calcium in postmenopausal women, which may be due to the independent effects of estrogen on coronary vessel walls.
Inflammatory Mediators Are Increased in Leukocytes of IVS-I-6 (T→C) Homozygous β-Thalassemia Intermedia.
Authors: Marcos André C Bezerra, Carla Fernanda Franco-Penteado, Carolina Lanaro, Mariana R. B. Mello, Sheley Gambero, Dulcinéia M Albuquerque, Kleber Yotsumoto Fertrin, Sara T.O Saad, Aderson S Araujo, Fernando Ferreira Costa
Journal: Blood (2009)
Frequency of CTLA-4 Receptor Ligand (CD86, B7.2) -Positive Plasmacytoid Dendritic Cells Predicts Risk of Disease Recurrence after Tyrosine-Kinase Inhibitor Discontinuation in Chronic Myeloid Leukemia: Results from a Prospective Substudy of the Euroski Trial
Authors: Andreas Burchert, Sabrina Inselmann, Susanne Saussele, Christian T. Dietz, Martin C. Müller, Ekkehard Eigendorff, Tim H. Brümmendorf, Cornelius Waller, Jolanta Dengler, Maria Elisabeth Goebeler, Regina Herbst, Gernot Freunek, Stefan Hanzel, Thomas Illmer, Ying Wang, Andreas Neubauer, Thoralf Lange, Andreas Hochhaus, Finkernagel Florian, Cornelia A. Brendel, Joelle Guilhot, Francois Xavier Mahon, Christin Schütz
Journal: Blood (2015)
The Safety and the Risk of Allogeneic Bone Marrow and Peripheral Blood Stem Cell Donation; Results of Nation-Wide Consecutive Pre-Transplant Registration of Related Donors in Japan.
Authors: Shunichi Kato, Yoshihisa Kodera, Kazuhito Yamamoto, Mine Harada, Nobuyuki Hamajima, Shigetaka Asano, Yasuo Ikeda, Masahiro Imamura, Yasuo Morishima, Keisei Kawa, Tatsutoshi Nakahata, Mitsune Tanimoto, Shintaro Shiobara, Hiroo Dohy, Sun-Won Kim, Yoshinobu Kanda
Journal: Blood (2007)
Cardiac Iron Overload and Heart Function by CMR In Different Phenotypic Groups of Thalassemia Major Patients
Authors: Maria Chiara Dell'Amico, Antonella Meloni, Aldo Filosa, Giuseppe Rossi, Vincenzo Positano, Brunella Favilli, Daniele De Marchi, Teodosio Grippo, Roberto Trunfio, Aurelio Maggio, Massimo Lombardi, Alessia Pepe
Journal: Blood (2010)
Regulation of Tissue Factor by NF-kB Transcription Factor p50 Is Essential for the Pathogeneses of Deep Vein Thrombosis and Arterial Restenosis.
Authors: Jian-Guo Geng, Jian-Guo Wang, Nigel Mackman, Arne Slungaard, Yuqing Huo, Nigel S. Key
Journal: Blood (2006)
Transmission of Extensively Drug-Resistant Tuberculosis in South Africa
Authors: N. Sarita Shah, Sara C. Auld, James C.M. Brust, Barun Mathema, Nazir Ismail, Pravi Moodley, Koleka Mlisana, Salim Allana, Angela Campbell, Thuli Mthiyane, Natashia Morris, Primrose Mpangase, Hermina van der Meulen, Shaheed V. Omar, Tyler S. Brown, Apurva Narechania, Elena Shaskina, Thandi Kapwata, Barry Kreiswirth, Neel R. Gandhi
Journal: New England Journal of Medicine (2017)

Drug-resistant tuberculosis threatens recent gains in the treatment of tuberculosis and human immunodeficiency virus (HIV) infection worldwide. A widespread epidemic of extensively drug-resistant (XDR) tuberculosis is occurring in South Africa, where cases have increased substantially since 2002. The factors driving this rapid increase have not been fully elucidated, but such knowledge is needed to guide public health interventions.
[18 F]-Fludarabine Positron Emission Tomography in Diffuse Large B-Cell Lymphoma (DLBCL) Patients: Results of a Phase I Study
Authors: Sylvain P Chantepie, Narinée Hovhannisyan, Stéphane Guillouet, Alain Manrique, Oumedaly Reman, Louisa Barre, Michel Leporrier
Journal: Blood (2015)
<i>Notes from the Field</i>: Use of Social Media as a Communication Tool During a Mumps Outbreak — New York City, 2015
Authors: Beth M. Isaac, Jane R. Zucker, Jennifer MacGregor, Mekete Asfaw, Jennifer L. Rakeman, Jie Fu, Bisram Deocharan, Dakai Liu, Jennifer B. Rosen
Journal: MMWR Morbidity and Mortality Weekly Report (2017)
Non-Transferrin-Bound Iron and Oxidative Stress Are Related to the Degree of Erythropoiesis in Patients with Thalassemia Intermedia.
Authors: Antonios Kattamis, Christina Lazaropoulou, Emmanuel Kanavakis, Vassilis Ladis, George Paleologos, Alexandra Stamoulakatou, Christos Kattamis, Ioannis Papassotiriou
Journal: Blood (2006)
Allogeneic Stem Cell Transplantation in Congenital Hemoglobinopathies – A Curative Approach When Performed as a Primary Therapeutic Modality: A Single Center Experience.
Authors: Ronit Elhasid, Irina Zaidman, Abdalla Khalil, Tsila Zuckerman, Nuhad Haddad, Tamar Katz, Myriam Ben Arush, Jacob M. Rowe
Journal: Blood (2009)
Galiximab (anti-CD80 mAb)-Induced Cell Triggering Results in the Inhibition of Constitutive NF-Kb Activity in Raji: Contrasting Roles of Snail and RKIP in the Regulation of Drug/Immune Resistance
Authors: Melisa Martinez-Paniagua, Mario I. Vega, Sara Huerta-Yepez, Stavroula Baritaki, James R. Berenson, Haris Hariharan, Benjamin Bonavida
Journal: Blood (2008)
Long-Term Results of Cytarabine-Containing Induction Followed By Consolidation with Autologous Stem Cell Transplant and Rituximab Maintenance As Primary Treatment for Mantle Cell Lymphoma
Authors: Umberto Falcone, Shaheena Bashir, Khalil Al-Farsi, Laurie Watkins, C. Denise Turvey, Norman Franke, Armand Keating, Michael Crump, John Kuruvilla
Journal: Blood (2015)
Multiparameter Flow Cytometric Analysis Reveals Aberrant Phosphorylation of a Network of Effector Molecules in Defined Populations of Kras Mutant Bone Marrow.
Authors: Margaret E.M. Van Meter, Ernesto Diaz-Flores, Joehleen A. Archard, Nikesh Kotecha, Amit J. Sabnis, Jonathan M. Irish, Garry P. Nolan, Kevin M. Shannon, Benjamin S. Braun
Journal: Blood (2005)
CRISPR-Cas9 gene repair of hematopoietic stem cells from patients with X-linked chronic granulomatous disease
Authors: Suk See De Ravin, Linhong Li, Xiaolin Wu, Uimook Choi, Cornell Allen, Sherry Koontz, Janet Lee, Narda Theobald-Whiting, Jessica Chu, Mary Garofalo, Colin Sweeney, Lela Kardava, Susan Moir, Angelia Viley, Pachai Natarajan, Ling Su, Douglas Kuhns, Kol A. Zarember, Madhusudan V. Peshwa, Harry L. Malech
Journal: Science Translational Medicine (2017)

CRISPR-mediated gene repair of hematopoietic stem cells from patients with X-linked chronic granulomatous disease resulted in functional human leukocytes in mice after transplantation.
Undertriage of Firearm-Related Injuries in a Major Metropolitan Area
Authors: Allison Lale, Allison Krajewski, Lee S. Friedman
Journal: JAMA Surgery (2017)

National anatomic triage criteria prescribe specific transport rules for injured patients. However, there is limited information about patients with firearm-related injuries undertriaged to nondesignated facilities (ie, hospitals without specialized trauma teams or units), including what clinical outcomes are achieved and how many are transferred to a higher level of care. Without these data, it is difficult to make informed regional or national policy decisions about triage practices. Undertriage of firearm-related injuries is a good model for evaluating the undertriage of patients with trauma because the anatomic triage criteria for patients with firearm-related injuries are simple.To evaluate the prevalence, spatial distribution, and clinical outcomes of undertriage of firearm-related injuries.This study is a retrospective analysis of firearm-related injuries in residents of Cook County, Illinois, from January 1, 2009, to December 31, 2013. Outpatient and inpatient hospital databases were used. Participants included patients with International Classification of Diseases, Ninth Revision, Clinical Modification firearm-related cause-of-injury codes. Data were collected all at once in August 2014. Data analysis took place from March 12, 2015, to February 1, 2016.Undertriaged cases were defined as patients who met the national anatomic triage criteria for transfer to higher-level trauma center care. Spatial distribution, injury severity, and clinical outcomes, including death, were analyzed.Of the 9886 patients included in this analysis, 8955 (90.6%) were male, 7474 (75.6%) were African American, and 5376 (54.4%) were aged 15 to 24 years.In Cook County, Illinois, where there are 19 trauma centers, 2842 of 9886 (28.7%) firearm-related injuries were initially treated in nondesignated facilities. Among the 4934 cases with firearm-related injury who met the anatomic triage criteria, 884 (17.9%) received initial treatment at a nondesignated facility and only 92 (10.4%) were transferred to a designated trauma center. Significant spatial clustering was identified on the west side of Chicago and in the southern parts of Chicago and Cook County. In the multivariable models, patients treated in nondesignated facilities were less likely to die than were patients treated in designated trauma centers.Undertriage of firearm-related injuries was much more prevalent than expected. Although the likelihood of dying during hospitalization was greater among patients treated in designated trauma centers, these patients were substantially in worse condition across all measures of injury severity. A smaller proportion of patients treated in designated trauma centers died during the first 24 hours of hospitalization. This study highlights the need for better regional coordination, especially with interhospital transfers, as well as the importance of assessing the distribution of emergency medical services resources to make the trauma care system more effective and equitable.
Idiopathic Ventricular Arrhythmias Originating From the Aortic Root
Authors: Takumi Yamada, H. Thomas McElderry, Harish Doppalapudi, Yoshimasa Murakami, Yukihiko Yoshida, Naoki Yoshida, Taro Okada, Naoya Tsuboi, Yasuya Inden, Toyoaki Murohara, Andrew E. Epstein, Vance J. Plumb, Satinder P. Singh, G. Neal Kay
Journal: Journal of the American College of Cardiology (2008)
Impact of Day 28 Absolute Lymphocyte Count on Outcome of Adult Patients with Acute Myeloid Leukemia
Authors: Naresh Bumma, Jing Ai, Xuefei Jia, Sean Hobson, Donna Abounader, Mikkael A. Sekeres, Matt E. Kalaycio, Ron Sobecks, Aaron Gerds, Betty K. Hamilton, Sudipto Mukherjee, Hetty E. Carraway, Shawnda Tench, Edward A. Copelan, Anjali S. Advani
Journal: Blood (2014)
Report On Excessive Induction Toxicity in Infants with ALL Enrolled On COG Protocol AALL0631: A Children's Oncology Group Study.
Authors: Patrick Brown, Joanne M. Hilden, Zoann E. Dreyer, Naomi J. Winick, Wanda Salzer, Elizabeth Raetz, Lillian Sung, Theoklis E Zaoutis, Tamekia Jones, Meenakshi Devidas, Paola De Lorenzo, Maria Grazia Valsecchi, Rob Pieters, William L. Carroll, Stephen P Hunger
Journal: Blood (2009)
Evaluation of MMR Concordance Based on Either International Scale (IS) or National Comprehensive Cancer Network (NCCN) Criteria Using Reconstructed “Virtual” CML Patient Profiles From the REVEAL BCR-ABL Methods Comparison Study,
Authors: Poluru L. Reddy, Paul Choppa, Mike M. Moradian, Nicholas T. Potter, Michael M. Quigley, Christopher D. Watt, Holger Höfling, Brian Manning, Andre Mignault, Brian Mullaney, Diego Ossa, Andrew Stein, Sha-Sha Wang, Feng Yang, Meir Wetzler
Journal: Blood (2011)
Tryptase-catalyzed core histone truncation: A novel epigenetic regulatory mechanism in mast cells
Authors: Fabio R. Melo, Ola Wallerman, Aida Paivandy, Gabriela Calounova, Ann-Marie Gustafson, Benjamin R. Sabari, Giuliano Zabucchi, C. David Allis, Gunnar Pejler
Journal: Journal of Allergy and Clinical Immunology (2017)

Mast cells are key effector cells in allergic reactions. When activated to degranulate, they release a plethora of bioactive compounds from their secretory granules, including mast cell-restricted proteases such as tryptase. In a previous study, we showed that tryptase, in addition to its intragranular location, can be found within the nuclei of mast cells where it truncates core histones at their N-terminal ends.Considering that the N-terminal portions of the core histones constitute sites for posttranslational modifications of major epigenetic impact, we evaluated whether histone truncation by tryptase could have an impact on epigenetic events in mast cells.Mast cells were cultured from wild-type and tryptase null mice, followed by an assessment of their profile of epigenetic histone modifications and their phenotypic characteristics.We show that tryptase truncates nucleosomal histone 3 and histone 2B (H2B) and that its absence results in accumulation of the epigenetic mark, lysine 5-acetylated H2B. Intriguingly, the accumulation of lysine 5-acetylated H2B was cell age-dependent and was associated with a profound upregulation of markers of non-mast cell lineages, loss of proliferative control, chromatin remodeling as well as extensive morphological alterations.These findings introduce tryptase-catalyzed histone clipping as a novel epigenetic regulatory mechanism, which in the mast cell context may be crucial for maintaining cellular identity.
Phosphorylation of Tyrosine 340 in the Plekstrin Homology Domain of RIAM Is Required for Translocation of RIAM to the Plasma Membrane, Phosphorylation of RIAM-Associated PLC-g1 and LFA-1 Activation
Authors: Duygu Sari, Niko Tsopoulidis, John M. Asara, Nikolaos Patsoukis, Vassiliki A. Boussiotis
Journal: Blood (2014)
Atherosclerotic Cardiovascular Risk in Adult Patients with Hemophilia: What We Can Do to Reduce Risk of Cardiovascular Events? Implementation of 2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol in Patients with Hemophilia
Authors: Kamila Izabela Cisak, Jianmin Pan, Shesh Nath Rai, Patricia Ashby, Vivek R. Sharma
Journal: Blood (2015)
Phase I Dose-Escalation Trial of BI 2536, a Polo-Like Kinase 1 Inhibitor, in Relapsed and Refractory Non-Hodgkin’s Lymphoma
Authors: Julie M. Vose, Anas Young, Jonathan W. Friedberg, Edmund K. Waller, Bruce D. Cheson, Dirk Trommeshauser, Gerd Munzert
Journal: Blood (2008)
Thulium laser in interventional endoscopy: animal and human studies
Authors: Gian Tontini, Helmut Neumann, Luca Pastorelli, Luisa Spina, Flaminia Cavallaro, Paola Soriani, Alessandro Rimondi, Barbara Bruni, Claudio Clemente, Filippo Fagnani, Pavlos Lagoussis, Luca Carmignani, Maurizio Vecchi
Journal: Endoscopy (2017)

Background and study aims The thulium laser system (TLS) is an emerging surgical tool. The 2-μm wavelength provides a confined coagulation depth (0.2 - 0.4 mm) to reduce the potential for inadvertent injuries. For the first time ever, we assessed TLS feasibility for endoscopic hemostasis ex vivo in pigs. In addition, we performed the first in vivo hemostatic treatments in humans. Patients and methods Tissue damage induced by TLS using different settings and optical fibers was compared to that from argon plasma coagulation (APC) in established ex vivo animal models. Three consecutive patients with complex nonvariceal upper gastrointestinal bleedings were treated and followed up. Results No deep submucosal injury was observed in animal models. The TLS showed a progressive penetration depth with increased power outputs and tissue exposures but very limited vertical tissue injury (0.1 - 2.0 mm) and lateral spreading damage (0.1 - 0.3 mm and 0.2 - 0.7 mm using the 365-µm and 550-µm fibers, respectively). In vivo, endoscopic hemostasis with TLS was always successful without complications. Conclusions The TLS has proven to be very precise and easy to use. This novel technique appears to be a promising tool for advanced interventional endoscopy.
Incidence of Adverse Drug Reactions Related to Immune Thrombocytopenia Drugs. A Prospective Cohort Study
Authors: Salim Mezaache, Thibault Comont, Johanne Germain, François Montastruc, Natacha Brun, Claire Dingremont, Claire Dingremont, Brice Castel, Sophie Arista, Serge Madaule, Philippe Montané de la Roque, Laurent Prudhomme, Laurent Sailler, Laurent Balardy, Cecile Borel, Stéphane Sire, Guillaume Martin-Blondel, Laurent Alric, Miguel Carreiro, Francis Gaches, Patrick Giraud, Maryse Lapeyre-Mestre, Bertrand Godeau, Odile Beyne-Rauzy, Daniel Adoue, Guillaume Moulis
Journal: Blood (2015)
A Phase I Study of Vorinostat in Combination with Lenalidomide and Dexamethasone in Patients with Relapsed or Refractory Multiple Myeloma
Authors: David Siegel, Donna Weber, Constantine S. Mitsiades, Syed Rizvi, Jose Garcia-Vargas, Jason Howe, David Reiser, Kenneth C. Anderson, Paul Richardson
Journal: Blood (2008)
A Niche-Based Cell Mutagenesis Assay Identifies ABL-Kinase Mutations Appearing in BCR-ABL T315I-Mutated Leukemic Cells Treated with Ponatinib.
Authors: Djamel Aggoune, Nathalie Sorel, Marie Laure Bonnet, Jean-Claude Chomel, Ali G Turhan
Journal: Blood (2012)
Novel, 2ND Generation Histone Deacetylase (HDAC) Inhibitor JNJ-26481585 Exhibits Potent Antitumor Activity Against Chronic Lymphocytic Leukemia Cells In-Vitro and Ex-Vivo.
Authors: Kurt Bommert, Stefan Knop, Janine Arts, Peter King, Martin Page, Eugen Leo, Ralf Bargou
Journal: Blood (2007)
Lenalidomide In Combination with the Activin Receptor Type II Murine Fc Protein RAP-011: Preclinical Rationale for a Novel Anti-Myeloma Strategy
Authors: Sonia Vallet, Kishan Patel, Diana Cirstea, Katie Luly, Samantha Pozzi, Loredana Santo, Homare Eda, Jasbir Seehra, Anuj Mahindra, David T. Scadden, Noopur Raje
Journal: Blood (2010)
Targeting STAT1 Separates Graft-Versus-Host Disease (GVHD) and Graft-Versus-Leukemia (GVL) Effects in Mice
Authors: Caisheng Lu, Huihui Ma, MeiHua Jin, Ailing Liu, Shirong Li, Suzanne Lentzsch, Markus Y. Mapara
Journal: Blood (2011)