THE INFLUENCE OF GONADAL HORMONES ON SERUM LIPIDS AND LIPOPROTEINS: STUDIES IN NORMAL AND HYPOGONADAL SUBJECTS
Authors: R H FURMAN, R P HOWARD
Journal: Annals of Internal Medicine (1957)

Article1 November 1957THE INFLUENCE OF GONADAL HORMONES ON SERUM LIPIDS AND LIPOPROTEINS: STUDIES IN NORMAL AND HYPOGONADAL SUBJECTSROBERT H. FURMAN, M.D., F.A.C.P., R. PALMER HOWARD, M.D., F.A.C.P.ROBERT H. FURMAN, M.D., F.A.C.P.Search for more papers by this author, R. PALMER HOWARD, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-47-5-969 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptClinicians have known for almost 200 years that the manifestations of coronary atherosclerosis are much more frequent in men than in women. Numerous autopsy studies have disclosed the disease in men earlier in life and in a more severe form than is the case with women, although anatomically this sex difference is somewhat less impressive than it is clinically. Autopsy studies on oophorectomized women, on the other hand, reveal an incidence and severity of coronary atherosclerosis more closely resembling that noted in men.1, 2Of interest and relevance are the opinions of White3and Gertler,4that there is less evidence...Bibliography1. WuestDryEdwards JHTJJE: The degree of coronary atherosclerosis in bilaterally oophorectomized women, Circulation 7: 801, 1953. CrossrefMedlineGoogle Scholar2. RivenDimitroff AUSP: The incidence and severity of atherosclerosis in estrogen-treated males, and in females with a hypoestrogenic or hyperestrogenic state, Circulation 9: 533, 1954. CrossrefMedlineGoogle Scholar3. White PD, discussion, in Barr, D. P., Russ, E. M., and Eder, H. A.: Influence of estrogens on lipoproteins in atherosclerosis, Tr. A. Am. Physicians 65: 102, 1952. MedlineGoogle Scholar4. Gertler MM: Personal communication. Google Scholar5. Eilert ML: The effects of estrogens upon the partition of the serum lipids in female patients, Am. 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Author, Article, and Disclosure InformationAffiliations: Oklahoma City, Oklahoma*From the Symposium on the Pathogenesis of Coronary Heart Disease, presented at the Thirty-eighth Annual Session of The American College of Physicians, Boston, Massachusetts, April 10, 1957.From the Cardiovascular and the Endocrinology and Metabolism Sections of the Oklahoma Medical Research Foundation, and the Department of Medicine, University of Oklahoma School of Medicine, Oklahoma City, Oklahoma.This study was supported in part by research grants from the National Heart Institute (H-1429, H-1561 and H-1694) and the National Institute of Arthritis and Metabolic Diseases (A-179), the Oklahoma State Heart Association, the Ayerst Laboratories, New York, N. Y., and the Smith, Kline and French Foundation, Philadelphia.Requests for reprints should be addressed to Robert H. Furman, M.D., The Oklahoma Medical Research Foundation, 825 Northeast Thirteenth Street, Oklahoma City 4, Oklahoma. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byHyperlipidaemia and premature coronary artery disease associated with sex-change in a female.Physiology of Stress and Regeneration in Job Related Cardiovascular IllnessThe Pathogenesis of HypercholesterolemiaWALTER M. BORTZ, M.D.Augmented release of hepatic triglycerides with anabolic steroids in patients with fatty liverEffect of androgens on serum lipids and lipoproteinsEffect of oxandrolone on plasma lipids and lipoproteins of patients with disorders of lipid metabolismBibliographyChapter 16. AtherosclerosisSerum lipoproteins in hydatidiform moleGonadal Hormones and Lipid MetabolismEffects of ethyl chlorophenoxyisobutyrate, alone or with androsterone (Atromid) on serum lipids, lipoproteins and related metabolic parameters in normal and hyperlipidemic subjectsHypocholesterolemic AgentsEFFECT OF BILATERAL OVARIECTOMY ON CORONARY-ARTERY DISEASE AND SERUM-LIPID LEVELSEFFECTS OF SEX STEROIDS ON LIPIDSCholesterol and Its Relation to AtherosclerosisModification of the Effects of Adrenal Cortical Steroids and Androgens on Serum Lipids and Lipoproteins by Caloric Supplementation and by Isocaloric Substitution of Carbohydrate for Dietary ProteinVariations in the Serum Total Cholesterol and Hematocrit Values in Normal Women During the Menstrual CycleREFERENCESTHE PHYSIOLOGY OF THE CIRCULATING CHOLESTEROL AND LIPOPROTEINSHormonal Aspects of Coronary Artery Disease 1 November 1957Volume 47, Issue 5Page: 969-977KeywordsAutopsyCardiology and cardiovascular diseasesCholesterolEndocrinologyHeart diseasesHormonesLipoproteinsLongitudinal studiesStable coronary artery diseaseUltracentrifugation ePublished: 1 December 2008 Issue Published: 1 November 1957 PDF downloadLoading ...