The Relationship of Cardiovascular Disease to Hyperglycemia
Authors: LEON D. OSTRANDER
Journal: Annals of Internal Medicine (1965)

Article1 June 1965The Relationship of Cardiovascular Disease to HyperglycemiaLEON D. OSTRANDER JR., M.D., F.A.C.P., THOMAS FRANCIS JR., M.D., SC.D., NORMAN S. HAYNER, M.D., MARCUS O. KJELSBERG, PH.D., FREDERICK H. EPSTEIN, M.D.LEON D. OSTRANDER JR., M.D., F.A.C.P., THOMAS FRANCIS JR., M.D., SC.D., NORMAN S. HAYNER, M.D., MARCUS O. KJELSBERG, PH.D., FREDERICK H. EPSTEIN, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-62-6-1188 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe high prevalence of vascular disease among diabetics has long been recognized and has become increasingly important since the acute complications of diabetes, acidosis, and infection have been controlled. With a longer life span cardiovascular disease is now the major complication of diabetes. Only 17% of diabetics died of vascular disease in 1914, but by 1957 it was the cause of death in 77% of the patients in one large series (1). Besides the well-known capillary lesions, the vascular complications have included coronary and peripheral atherosclerotic occlusive disease, hypertension, and cerebrovascular disease.The higher prevalence and greater severity of coronary...References1. ROOTBRADLEY HFRF: Cardiovascular-renal disease, in The Treatment of Diabetes Mellitus, 10th ed., edited by JOSLIN, E. P., ROOT, H. F., WHITE, P., MARBLE, A. Lea & Febiger, Philadelphia, 1959, p. 408. Google Scholar2. LISAMAGIDAYGALLOWAYHART JRMIJF: Arteriosclerosis with diabetes mellitus. JAMA 120: 192, 1942. CrossrefGoogle Scholar3. STEARNSSCHLESINGERRUDY SMJA: Incidence and clinical significance of coronary artery disease in diabetes mellitus. Arch. Intern. Med. (Chicago) 80: 463, 1947. CrossrefGoogle Scholar4. BELL ET: A post mortem study of vascular disease in diabetics. Arch. Path. 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OSTRANDERJR., M.D., F.A.C.P.; THOMAS FRANCISJR., M.D., SC.D.; NORMAN S. HAYNER, M.D.; MARCUS O. KJELSBERG, PH.D.; FREDERICK H. EPSTEIN, M.D.Affiliations: Ann Arbor, MichiganFrom the Department of Epidemiology, The University of Michigan School of Public Health, Ann Arbor, Mich.This study was supported by Program Project Grant HE-06378 from the National Heart Institute, National Institutes of Health, U. S. Public Health Service, and Research Career Award HE-K6-6748 to Dr. Epstein from the National Heart Institute, National Institutes of Health, U. S. Public Health Service, Bethesda, Md.Requests for reprints should be addressed to Leon D. Ostrander, Jr., M.D., Department of Epidemiology, The University of Michigan, School of Public Health, Ann Arbor, Mich. 48104. 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NEFF, PH.D., WALTER D. BLOCK, PH.D., THOMAS FRANCIS JR., M.D., SC.D., FREDERICK H. EPSTEIN, M.D.Serum Insulin, Carbohydrate, and Lipid Abnormalities in Patients with Premature Coronary Heart DiseaseMANUEL TZAGOURNIS, M.D., JOHN F. SEIDENSTICKER, M.D., GEORGE J. HAMWI, M.D., F.A.C.P.Detection of coronary-prone subjects in a normal population by radioelectrocardiographic exercise testGLUCOSE TOLERANCE, AGE, AND CIRCULATING INSULINConstitutional and Environmental Factors Related to Serum Lipid and Lipoprotein LevelsWILLIAM R. HARLAN JR., M.D., ALBERT OBERMAN, M.D., ROBERT E. 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EPSTEIN, M.D., LEON D. OSTRANDER JR., M.D., F.A.C.P., BENJAMIN C. JOHNSON, M.D., DR. P.H., MILLICENT W. PAYNE, M.D., D.P.H., NORMAN S. HAYNER, M.D., M.P.H., JACOB B. KELLER, M.P.H., THOMAS FRANCIS JR., M.D., D.SC.Carbohydrate Metabolism in Cardiovascular DiseaseMARGARET J. ALBRINK, M.D.Acceptability of Vegetables in an Army Mess1 1 June 1965Volume 62, Issue 6Page: 1188-1198KeywordsCardiovascular diseasesCardiovascular therapyCareers in researchCerebrovascular diseasesEpidemiologyHyperglycemiaHypertensionMedical servicesPrevention, policy, and public healthVascular diseases ePublished: 1 December 2008 Issue Published: 1 June 1965 PDF downloadLoading ...