CLINICAL MANIFESTATIONS AND STUDIES IN PARENCHYMATOUS HEPATITIS
Authors: Hugo A. Freund
Journal: Annals of Internal Medicine (1937)

Article1 February 1937CLINICAL MANIFESTATIONS AND STUDIES IN PARENCHYMATOUS HEPATITISHUGO A. FREUND, B.A., M.D., F.A.C.P.HUGO A. FREUND, B.A., M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-10-8-1144 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIt is a paradoxical fact that one of the most accessible and important organs of the body, the liver, is the one about which the least is known. The multiplicity of its functions is appreciated but little understood. Therefore, for practical as well as theoretic purposes, any data concerning liver function, metabolism and pathology are deserving of record.The baffling part of the liver problem lies in our inability to reproduce in animals conditions frequently found in man. Liver necrosis, hepatitis, cirrhosis, atrophy and regeneration have all been reproduced experimentally with varying degrees of success. These experimental lesions and their...Bibliography WELLS HG: The pathological anatomy of hydrazine poisoning, Jr. Exper. Med., 1908, x, 457-464. CrossrefGoogle Scholar UNDERHILLKLEINER FPIS: The influence of hydrazine upon intermediary metabolism in the dog, Jr. Biol. Chem., 1908, iv, 165-178. CrossrefGoogle Scholar UNDERHILLPRINCE FPAL: Studies in carbohydrate metabolism. V. The disappearance of sugar from solutions perfused through the heart of the normal rabbit, and of animals subjected to inanition and to the action of hydrazine, Jr. Biol. Chem., 1913-14, xvii, 299-304. Google Scholar UNDERHILLHOGAN FPAG: Studies in carbohydrate metabolism. VIII. The influence of hydrazine on the utilization of dextrose, Jr. Biol. Chem., 1915, xx, 203-215. CrossrefGoogle Scholar UNDERHILLMURLIN FPJR: Studies in carbohydrate metabolism. X. 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