CARDIAC ADAPTATIONS IN ACUTE PROGRESSIVE ANOXIA
Authors: Carl J. Wiggers
Journal: Annals of Internal Medicine (1941)

Article1 January 1941CARDIAC ADAPTATIONS IN ACUTE PROGRESSIVE ANOXIACARL J. WIGGERS, M.D., F.A.C.P.CARL J. WIGGERS, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-14-7-1237 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptCIRCULATORY REACTIONS IN MANThe reactions of the cardiovascular system in man to progressively diminishing oxygen have been repeatedly described, among others by Whitney,1Schneider,2Schneider and Truesdell,3Gellhorn,4and Armstrong.6While there are variations assignable to individual sensitivity, speed in development of anoxia, etc., the following reactions commonly occur in standard rebreathing tests: The heart rate increases, systolic pressure rises slightly and diastolic pressure either remains stationary or changes slightly in upward or downward directions. A dynamic analysis of such data indicates that the diminishing oxygen-carrying capacity of the blood is compensated by increased circulating volume as well as...References1. WHITNEY JL: Manual of Med. Research Lab. (Mineola, N. Y.), Gov't Printing Office, Washington, D. C., 1913. Medical studies in aviation. III. Cardiovascular observations, Jr. Am. Med. Assoc., 1918, lxxi, 1389. Google Scholar2. SCHNEIDER EC: Medical studies in aviation. II. Physiological observations and methods, Jr. Am. Med. Assoc., 1918, lxxi, 1384. Physiological effects of altitude, Physiol. Rev., 1921, i, 631. CrossrefGoogle Scholar3. SCHNEIDERTRUESDELL ECD: The circulatory responses of man to anoxemia, Am. Jr. Physiol., 1924, lxxi, 90. CrossrefGoogle Scholar4. GELLHORN E: Circulatory studies on anoxemia in man with respect to posture and CO2 , ANN. INT. MED., 1937, x, 1267. GELLHORN, E., and LAMBERT, E. H.: The vasomotor system in anoxia and asphyxia, 1939, University of Illinois Press, Urbana, Ill. 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