ANGINAL SYNDROME DURING SODIUM SUCCINATE THERAPY
Authors: C S DWYER, S KRONENBERG, M SAKLAD
Journal: Annals of Internal Medicine (1949)

Case Reports1 July 1949ANGINAL SYNDROME DURING SODIUM SUCCINATE THERAPYCLEMENT S. DWYER, M.D., SANFORD KRONENBERG, M.D., MEYER SAKLAD, M.D.CLEMENT S. DWYER, M.D.Search for more papers by this author, SANFORD KRONENBERG, M.D.Search for more papers by this author, MEYER SAKLAD, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-31-1-148 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe introduction into experimental clinical medicine of agents which take part in the oxidation-reduction systems of the body has stimulated the interest of clinicians in tissue metabolism and its mechanisms. Succinic acid salts have been discussed in the literature from the standpoint of their effects on oxidative processes in vitro and in the living animal. Various investigators are studying their possible application in the treatment of certain conditions, notably barbiturate intoxication and anesthesia,1, 2, 3, 4, 5, 6 hypoxia,7, 8 and rheumatic fever,9 but the bibliography pertaining to their use is still meager.Comprehensive evaluation of such agents requires a...Bibliography1. SOSKINTAUBENHAUS SM: Sodium succinate as antidote for barbiturate poisoning and in control of duration of barbiturate anesthesia, Jr. Pharm. and Exper. Therap., 1943, lxxviii, 49-55. Google Scholar2. LARDYHANSENPHILLIPS HARGPH: Ineffectiveness of sodium succinate in control of duration of barbiturate anesthesia, Proc. Soc. Exper. Biol. and Med., 1944, lv, 277-278. CrossrefGoogle Scholar3. BEYERLATVEN KHAR: Evaluation of influence of succinate and malonate on barbiturate hypnosis, Jr. Pharm. and Exper. Therap., 1944, lxxxi, 203-208. Google Scholar4. PINSCHMIDTRAMSEYHAAG NWHHB: Studies on the antagonism of sodium succinate to barbiturate depression, Jr. Pharm. and Exper. Therap., 1945, lxxxiii, 45-52. Google Scholar5. BARRETT RH: Unpublished data. Google Scholar6. CORSONKOPPANYIVIVINO SATAE: Studies on barbiturates, XXVIII. Effect of succinate and fumarate in experimental barbiturate poisoning, Anesth. and Analg., 1945, xxiv, 177-192. Google Scholar7. PROGERAISNERSQUIRES SMRB: The prevention of electrocardiographic evidence of myocardial anoxemia by chemical means, Jr. Clin. Invest., 1942, xxi, 630. Google Scholar8. PROGER S: The use of respiratory catalysts particularly succinic acid in tissue anoxia, Bull. New England Med. Center, 1943, v, 80. Google Scholar9. GUBNERSZUCS RM: Therapeutic measures in rheumatic fever, New England Jr. Med., 1945, ccxxiii, 652-657. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Providence, Rhode Island*Received for publication February 21, 1947.From the Rhode Island Hospital, Providence.The sodium succinate (Soduxin) used in this study was supplied through the courtesy of Brewer & Co., Inc. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe Socioeconomic Role of the Local Foreign Minorities in Modern Egypt, 1805–1961Sudden Death after the Administration of Sodium SuccinateCLINICAL EVALUATION OF DISODIUM SUCCINATE, INCLUDING A REPORT ON ITS INEFFECTIVENESS IN TWO CASES OF SEVERE BARBITURATE POISONING AND SOME TOXICOLOGIC NOTES ON OTHER SUCCINATE SALTS*MORRIS ZUCKERBROD, M.D., IRVING GRAEF, M.D. 1 July 1949Volume 31, Issue 1Page: 148-153KeywordsIntoxicationSaltsSodium ePublished: 1 December 2008 Issue Published: 1 July 1949 PDF downloadLoading ...