Ischemic Colitis Associated with Decongestant Use
Authors: Gary R. Lichtenstein, Nelson S. Yee
Journal: Annals of Internal Medicine (2000)

Letters18 April 2000Ischemic Colitis Associated with Decongestant UseGary R. Lichtenstein, MD and Nelson S. Yee, MD, PhDGary R. Lichtenstein, MDHospital of the University of Pennsylvania; Philadelphia, PA 19104-4283 (Lichtenstein)Hospital of the University of Pennsylvania; Philadelphia, PA 19104-4283 (Yee) and Nelson S. Yee, MD, PhDHospital of the University of Pennsylvania; Philadelphia, PA 19104-4283 (Lichtenstein)Hospital of the University of Pennsylvania; Philadelphia, PA 19104-4283 (Yee)Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-132-8-200004180-00030 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Pseudoephedrine is a widely used over-the-counter nasal decongestant that has been associated with transient ischemic colitis in a woman who used oral contraceptives (1) and four perimenopausal women (2). It is unclear in those reports whether the changing levels of estrogen and progesterone and the associated thromboembolic effect contributed to the colitis (3). We report a case of ischemic colitis in a man who had used pseudoephedrine and did not have underlying thrombophilia or vasculitis.A 33-year-old man presented with abrupt onset of lower abdominal cramps, diarrhea, and hematochezia of 2 days' duration. He had chronic asthma ...References1. Schneider RP. Ischemic colitis caused by decongestant? J Clin Gastroenterol. 1995;21:335-6. CrossrefMedlineGoogle Scholar2. Dowd J, Bailey D, Moussa K, Nair S, Doyle R, Culpepper-Morgan JA. Ischemic colitis associated with pseudoephedrine: four cases. Am J Gastroenterol. 1999;94:2430-4. CrossrefMedlineGoogle Scholar3. Deana DG, Dean PJ. Reversible ischemic colitis in young women. Association with oral contraceptive use. Am J Surg Pathol. 1995;19:454-62. CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Hospital of the University of Pennsylvania; Philadelphia, PA 19104-4283 (Lichtenstein)Hospital of the University of Pennsylvania; Philadelphia, PA 19104-4283 (Yee) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByIn search of an ideal drug for safer treatment of obesity: The false promise of pseudoephedrineAcute Ischemic Colitis due to Oral PhenylephrineReview article: the pharmacological causes of colon ischaemiaPseudoephedrine Associated Ischemic ColitisEphedra, ephedrine, and pseudoephedrineEndoscopic mucosal biopsy – histopathological interpretationAcute ischaemic colitis associated with oral phenylephrine decongestant usePseudoephedrine-induced ischemic colitis: Case report and literature reviewSystematic review on the treatment of ischaemic colitisA Case of Ischemic Colitis Associated with the Herbal Food Supplement Ma HuangPharmacologically Mediated Colon IschemiaEphedra, ephedrine, and pseudoephedrineColite ischémiqueColite ischémique sévère après prise de Rhinadvil® chez une jeune fille de 15 ansProbable Ischemic Colitis Caused by Pseudoephedrine with Tramadol as a Possible Contributing FactorIschemic Colitis in a Young PatientIncidence of Colonic Ischemia, Hospitalized Complications of Constipation, and Bowel Surgery in Relation To Use of Alosetron HydrochlorideDiagnosis and misdiagnosis of inflammatory bowel diseaseDrugs affecting autonomic functions or the extrapyramidal systemNew developments in colonic ischemiaRecurrent ischaemic colitis associated with pseudoephedrine usePseudoephedrine 18 April 2000Volume 132, Issue 8Page: 682KeywordsColitisDiarrheaEdemaOral contraceptive therapyPathogensProgesteroneProteinsRisk managementUltrasound imagingVasculitis Issue Published: 18 April 2000 CopyrightCopyright © 2000 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...