The Biopsychosocial Model Thirty Years Later
Authors: Giovanni A. Fava, Nicoletta Sonino
Journal: Psychotherapy and Psychosomatics (2007)

As 30 years ago, the dominant model of disease today is biomedical, with molecular biology being the basic scientific discipline. Indeed, there has been a progressive decline of clinical observation as the primary source of scientific challenges [5] . Yet, the evidence supporting the biopsychosocial model has considerably increased over the years. A large body of research has documented the role of stressful life events and repeated or chronic environmental challenge in modulating individual vulnerability to illness [6] . The tendency to experience and communicate psychological distress in the form of physical symptoms and to seek medical help for them is a widespread clinical phenomenon that may involve up to 30 or 40% of medical patients and increases medical utilization and costs [7, 8] . Medically unexplained symptoms appear to be the rule in primary care [7, 8] and the traditional boundaries among medical specialties, based mostly on organ systems (e.g. cardiology, gastroenterology) appear to be more and more inadequate in dealing with symptoms and problems which cut across organ system subdivisions and require a holistic approach. Moreover, affective disturbances (such as depression, anxiety, hostility) and illness behavior, the ways in which individuals experience, perceive, evaluate and respond to their own health status, may affect the course, therapeutic response and outcome of a given illness episode [7] . Psychological well-being [9] was found to play a protective role in the dynamic balance between health and disease outlined by Engel [1] . The need to include considThirty years ago George L. Engel [1] highlighted the inadequacies and limitations of the traditional biomedical model and advocated the endorsement of a biopsychosocial approach. The article had a considerable impact on the scientific community and attracted nearly 1,900 citations over the years. The biopsychosocial model allows illness to be viewed as a result of interacting mechanisms at the cellular, tissue, organismic, interpersonal and environmental levels. Accordingly, the study of every disease must include the individual, his/her body and his/her surrounding environment as essential components of the total system [1, 2] . Psychosocial factors may operate to facilitate, sustain or modify the course of illness, even though their relative weight may vary from illness to illness, from one individual to another and even between 2 different episodes of the same illness in the same individual. The key characteristic of clinical science is its explicit attention to humanness, where ‘observation (outer viewing), introspection (inner viewing), and dialogue (interviewing) are the basic methodologic triad for clinical study and for rendering patient data scientific’ [3, p. 59]. Engel identified the biopsychosocial model as a more complete conceptual framework to guide clinicians in their everyday work with patients. He thought that the transition from the narrow biomedical model to the biopsychosocial model was the major challenge to medicine in the seventies [1] . Has the challenge been met? Not at all, as examined in a recent monograph on the biopsychosocial approach [4] .