Notice of Retraction: Ramipril Markedly Improves Walking Ability in Patients With Peripheral Arterial Disease
Authors: Adam Lawler, Christopher M. Reid, Peter A. Blombery, Bronwyn A. Kingwell
Journal: Annals of Internal Medicine (2015)

Retractions1 December 2015Notice of Retraction: Ramipril Markedly Improves Walking Ability in Patients With Peripheral Arterial DiseaseFREEThis retraction concerns the following article:ArticlesMay 2006Brief Communication: Ramipril Markedly Improves Walking Ability in Patients with Peripheral Arterial DiseaseFREEAnna A. Ahimastos, BSc(Hons), Adam Lawler, BSc, Christopher M. Reid, PhD, Peter A. Blombery, MB, PhD, and Bronwyn A. Kingwell, PhDAnna A. Ahimastos, BSc(Hons)From Baker Heart Research Institute, Alfred Hospital, and Monash University, Melbourne, Australia.Search for more papers by this author, Adam Lawler, BScFrom Baker Heart Research Institute, Alfred Hospital, and Monash University, Melbourne, Australia.Search for more papers by this author, Christopher M. Reid, PhDFrom Baker Heart Research Institute, Alfred Hospital, and Monash University, Melbourne, Australia.Search for more papers by this author, Peter A. Blombery, MB, PhDFrom Baker Heart Research Institute, Alfred Hospital, and Monash University, Melbourne, Australia.Search for more papers by this author, and Bronwyn A. Kingwell, PhDFrom Baker Heart Research Institute, Alfred Hospital, and Monash University, Melbourne, Australia.Search for more papers by this authorAdam Lawler, BSc, Christopher M. Reid, PhD, Peter A. Blombery, MB, PhD, and Bronwyn A. Kingwell, PhDAdam Lawler, BScSearch for more papers by this author, Christopher M. Reid, PhDSearch for more papers by this author, Peter A. Blombery, MB, PhDSearch for more papers by this author, and Bronwyn A. Kingwell, PhDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/M15-2625 SectionsAboutVisual AbstractPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Following admission of data fabrication by the first author, Anna Ahimastos, in a similar study of ramipril for patients with peripheral arterial disease (1), Baker IDI Heart and Diabetes Institute conducted an independent investigation of the trial, published in Annals in 2006 (2). Based on that investigation and our own analysis, we, the undersigned authors, wish to retract this article due to an inability to adequately validate primary data sources. Dr. Ahimastos maintains the integrity of the data and validity of reported results and has declined to answer additional questions. The investigation did not find culpability on our part, and we apologize unreservedly to the editors, reviewers, and readers of Annals of Internal Medicine. Given the clinical indications for ramipril and other angiotensin-converting enzyme inhibitors, we believe there is no risk that these possibly invalid trial data harmed trial participants or patients with peripheral arterial disease taking ramipril.Editor's Note: The above-named authors agreed to this retraction. Attempts on the part of the journal office to obtain input regarding this retraction from Dr. Ahimastos, first author of the retracted article, were unsuccessful.References1. Ahimastos AA, Walker PJ, Askew C, Leicht A, Pappas E, Blombery P, et al. Effect of ramipril on walking times and quality of life among patients with peripheral artery disease and intermittent claudication: a randomized controlled trial. JAMA. 2013;309:453-60. [PMID: 23385271] doi:10.1001/jama.2012.216237 CrossrefMedlineGoogle Scholar2. Ahimastos AA, Lawler A, Reid CM, Blombery PA, Kingwell BA. Brief communication: ramipril markedly improves walking ability in patients with peripheral arterial disease: a randomized trial. Ann Intern Med. 2006;144:660-4. [PMID: 16670135]. doi:10.7326/0003-4819-144-9-200605020-00009 LinkGoogle Scholar Comments0 CommentsSign In to Submit A Comment Author, Article, and Disclosure InformationAffiliations: This article was published online first at www.annals.org on 6 November 2015. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoBrief Communication: Ramipril Markedly Improves Walking Ability in Patients with Peripheral Arterial Disease Anna A. Ahimastos , Adam Lawler , Christopher M. Reid , Peter A. Blombery , and Bronwyn A. Kingwell Metrics Cited byNotice of Retraction: Ramipril Markedly Improves Walking Ability in Patients With Peripheral Arterial Disease [Summary for Patients] 1 December 2015Volume 163, Issue 11Page: 884KeywordsAngiotensin converting enzyme inhibitorCardiovascular therapyClinical trialsHeart diseasesInformation storage and retrievalLongitudinal studiesWalking ePublished: 6 November 2015 Issue Published: 1 December 2015 Copyright & PermissionsCopyright © 2015 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...