Trimethoprim-Sulfamethoxazole and Bacterial Meningitis
Authors: ZOHEIR FARID
Journal: Annals of Internal Medicine (1976)

Letters1 January 1976Trimethoprim-Sulfamethoxazole and Bacterial MeningitisZOHEIR FARID, M.D., NABIL I. GIRGIS, M.D., WAGIH YASSIN, M.D., DAVID C. EDMAN, PH.D., WALTER F. MINER, M.D., M.P.H.ZOHEIR FARID, M.D.Search for more papers by this author, NABIL I. GIRGIS, M.D.Search for more papers by this author, WAGIH YASSIN, M.D.Search for more papers by this author, DAVID C. EDMAN, PH.D.Search for more papers by this author, WALTER F. MINER, M.D., M.P.H.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-84-1-50 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTrimethoprim-sulfamethoxazole has been used successfully in the treatment of a nocardial brain abscess (1) and was recently found to be also effective in the treatment of bacterial brain abscess (Ann Intern Med 82:812-813, 1975). During the past year we have had the opportunity of successfully treating five patients with bacterial meningitis with this combination.The five patients were referred to the Abbassia Fever Hospital, United States Naval Medical Research Unit No. 3 meningitis wards because of fever accompanied by severe headache and vomiting not responding to routine therapy. Three patients were drowsy and two were unconscious (Table 1). In every...References1. MADERAZOQUINTILIANI ER: Treatment of nocardial infection with trimethoprim-sulfamethoxazole. Am J Med 57:671-675, 1974 CrossrefMedlineGoogle Scholar2. SCHIFFMAN D: Evaluation of anti-infective combination trimethoprim-sulfamethoxazole (Bactrim, Septra). JAMA 231:635-637, 1975 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: U.S. Naval Medical Research Unit No. 3 Fleet Post Office New York 09527 Abbassia Fever Hospital Cairo Egypt PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited BySuccessful Therapy of Postneurosurgical Meningitis Caused by a Resistant Strain of Enterobacter AerogenesIn vitro and in vivo efficacy of the combination trimethoprim-sulfamethoxazole against clinical isolates of methicillin-resistant Staphylococcus aureusGram-negative Bacillary MeningitisTrimethoprim-Sulfamethoxazole for Bacterial MeningitisROBERT E. LEVITZ, M.D., RICHARD QUINTILIANI, M.D.Parenteral Trimethoprim/Sulfamethoxazole for Gram Negative Bacillary MeningitisClinical Pharmacokinetics of Co-trimoxazoleIn vitro activities of trimethoprim and sulfamethoxazole against Listeria monocytogenesTrimethoprim-Sulfamethoxazole Treatment of Multiantibiotic-Resistant Staphylococcal Endocarditis and MeningitisIntravenous Sulfamethoxazole-Trimethoprim: Pharmacokinetics, Therapeutic Indications, and Adverse ReactionsTrimethoprim-sulfamethoxazole therapy of experimental Escherichia coli meningitis in rabbitsMeningococciIntravenous trimethoprim-sulfamethoxazole in the treatment of serious infections in childrenDrugs Five Years Later: Trimethoprim-Sulfamethoxazole in the United StatesGARY P. WORMSER, M.D., GERALD T. KEUSCH, M.D.Newer Antibacterial and Antimycotic Drugs: Critical AppraisalTrimethoprim-Sulfamethoxazole for MeningitisJOHN A. ROBINSON, M.D. 1 January 1976Volume 84, Issue 1Page: 50-51KeywordsAbscessesBacterial meningitisBrainFeversHeadachesHyperthermiaMeningitisVomiting Issue Published: 1 January 1976 PDF DownloadLoading ...