INFLUENZA A PRIME: A CLINICAL STUDY OF AN EPIDEMIC CAUSED BY A NEW STRAIN OF VIRUS
Authors: E D KILBOURNE, J P LOGE
Journal: Annals of Internal Medicine (1950)

Article1 August 1950INFLUENZA A PRIME: A CLINICAL STUDY OF AN EPIDEMIC CAUSED BY A NEW STRAIN OF VIRUSEDWIN D. KILBOURNE, M.D., J. PHILIP LOGE, M.D.EDWIN D. KILBOURNE, M.D.Search for more papers by this author, J. PHILIP LOGE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-33-2-371 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Excerpt"Influenza," a term traditionally fraught with ambiguity and even today loosely applied to any acute, benign, febrile illness, is now recognized as a specific viral infection of the upper respiratory tract of man.The isolation, in 1933, of the specific etiological virus of influenza by Smith, Andrewes and Laidlaw1made possible for the first time attempts at definition of the clinical syndrome of this disease. Studies by Stuart-Harris et al.,2during the English epidemic of 1936-1937, established that patients proved to have been infected by influenza A virus presented the characteristic, if not pathognomonic, clinical picture of an abrupt, prostrating...Bibliography1. SmithAndrewesLaidlaw WCHPP: A virus obtained from influenza patients, Lancet 2: 66, 1933. CrossrefGoogle Scholar2. Stuart-HarrisAndrewesSmith CHCHW: A study of epidemic influenza: with special reference to the 1936-7 epidemic. Med. Research Council Special Report No. 228, 1938, His Majesty's Stationery Office, London. Google Scholar3. Stuart-HarrisSmithAndrewes CHWCH: The influenza epidemic of January-March, 1939, Lancet 1: 205, 1940. CrossrefGoogle Scholar4. FrancisMagillBeckRickard TTPDMER: Studies with human influenza virus, J. A. M. A. 109: 566, 1937. CrossrefGoogle Scholar5. Francis T: Epidemiological studies in influenza, Am. J. Pub. Health 27: 211, 1937. CrossrefGoogle Scholar6. Francis T: A new type of virus from epidemic influenza, Science 92: 405, 1940. CrossrefMedlineGoogle Scholar7. HorsfallHahnRickard FLRGER: Four recent influenza epidemics: an experimental study, J. Clin. Investigation 19: 379, 1940. CrossrefMedlineGoogle Scholar8. SalkSuriano JEPC: Importance of antigenic composition of influenza virus vaccine in protecting against the natural disease, Am. J. Pub. Health 39: 345, 1949. CrossrefGoogle Scholar9. FrancisSalkQuilligan TJEJJ: Experience with vaccination against influenza in the Spring of 1947. A preliminary report, Am. J. Pub. Health 37: 1013, 1947. CrossrefGoogle Scholar10. RasmussenStokesSmadel AFJCJE: The Army experience with influenza, 1946-1947. II. Laboratory aspects, Am. J. Hyg. 47: 142, 1948. MedlineGoogle Scholar11. SartwellLong PEAP: The Army experience with influenza, 1946-1947. I. Epidemiological aspects, Am. J. Hyg. 47: 135, 1948. MedlineGoogle Scholar12. LogeKilbourne JPED: Penicillin therapy of streptococcal pharyngitis, Ann. Int. Med. 29: 698, 1948. LinkGoogle Scholar13. Horsfall FL: The present status of the influenza problem, J. A. M. A. 120: 284, 1942. CrossrefGoogle Scholar14. Glover RE: Spread of infection from the respiratory tract of the ferret. II. Association of influenza A virus and streptococcus Group C, Brit. J. Exper. Path. 22: 98, 1941. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication August 6, 1949.From the Station Hospital, Fort Monmouth, New Jersey.The assistance of the Commission on Immunization of the Army Epidemiological Board is acknowledged.†Present address: The Hospital of the Rockefeller Institute for Medical Research. 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E. BURCH, M.D., F.A.C.P., AUBREY WHITE, M.D., WILLIAM MOGABGAB, M.D., F.A.C.P., LAWRENCE DIETLEIN, M.D.(b) Clinical and Laboratory Aspects of Epidemic InfluenzaDie Pneumonien 1 August 1950Volume 33, Issue 2Page: 371-379KeywordsInfluenza A virusRespiratory systemUpper respiratory tract infections ePublished: 1 December 2008 Issue Published: 1 August 1950 PDF downloadLoading ...