Rheumatoid Arthritis with Arteritis
Authors: ISRAELI A. JAFFE
Journal: Annals of Internal Medicine (1964)

Case Studies1 September 1964Rheumatoid Arthritis with ArteritisReport of a Case Treated with PenicillamineISRAELI A. JAFFE, M.D., F.A.C.P.ISRAELI A. JAFFE, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-61-3-556 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe development of an arteritis resembling polyarteritis nodosa in patients with rheumatoid arthritis has been well documented in the literature (1). An apparent increase in the prevalence of this syndrome has been ascribed to the widespread use of corticosteroids, which is believed to predispose to the development of disseminated vascular lesions (2, 3). Patients with this syndrome usually have subcutaneous nodules and very high titers of the rheumatoid factor, though many with high titer do not develop this complication (4). Peripheral neuropathy is usually the earliest manifestation of disseminated arteritis, and it is believed to be secondary to disease in...References1. BALL J: Rheumatoid arthritis and polyarteritis nodosa. Ann. Rheum. Dis. 13: 77, 1954. CrossrefGoogle Scholar2. KEMPERBAGENSTOSSSLOCUMB JWAHCH: Relationship of therapy with cortisone to the vascular lesions in rheumatoid arthritis. Ann. Intern. Med. 46: 831, 1957. LinkGoogle Scholar3. JOHNSONSMYTHHOLTLUCHENKOVALENTINE RLCJGWAE: Steroid therapy and vascular lesions in rheumatoid arthritis. Arthritis Rheum. 2: 224, 1959. CrossrefMedlineGoogle Scholar4. FRANKLINKUNKELWARD ECHGJR: Clinical studies of seven patients with rheumatoid arthritis and uniquely large amounts of rheumatoid factor. Arthritis Rheum. 1: 400, 1958. CrossrefMedlineGoogle Scholar5. IRBYADAMSTOONE RRAEC: Peripheral neuritis associated with rheumatoid arthritis. Arthritis Rheum. 1: 44, 1958. CrossrefMedlineGoogle Scholar6. 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Author, Article, and Disclosure InformationAffiliations: New York, New YorkFrom the New York Medical College, Flower and Fifth Avenues Hospitals, New York, New York.This study was supported by the New York City Health Research Council grant HRU 1097, The Arthritis and Rheumatism Foundation, and the U. S. Army Medical Research and Development Command (DA-49-193MD-2445).Requests for reprints should be addressed to Israeli A. Jaffe, M.D., New York Medical College, Flower and Fifth Avenues Hospitals, 5th Ave. and 106th St., New York, New York 10029. 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