Transfusion-Associated Acute Chagas Disease Acquired in the United States
Authors: Irene H. Grant, Jonathan W.M. Gold, Murray Wittner, Herbert B. Tanowitz, Carl Nathan, Klaus Mayer, Lillian Reich, Norma Wollner, Laurel Steinherz, Fereshteh Ghavimi, Richard J. O'Reilly, Donald Armstrong
Journal: Annals of Internal Medicine (1989)

Brief Reports15 November 1989Transfusion-Associated Acute Chagas Disease Acquired in the United StatesIrene H. Grant, MD, Jonathan W.M. Gold, MD, Murray Wittner, MD, PhD, Herbert B. Tanowitz, MD, Carl Nathan, MD, Klaus Mayer, MD, Lillian Reich, MD, Norma Wollner, MD, Laurel Steinherz, MD, Fereshteh Ghavimi, MD, Richard J. O'Reilly, MD, Donald Armstrong, MDIrene H. Grant, MD, Jonathan W.M. Gold, MD, Murray Wittner, MD, PhD, Herbert B. Tanowitz, MD, Carl Nathan, MD, Klaus Mayer, MD, Lillian Reich, MD, Norma Wollner, MD, Laurel Steinherz, MD, Fereshteh Ghavimi, MD, Richard J. O'Reilly, MD, Donald Armstrong, MDAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-111-10-849 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlthough a significant problem in Latin America (1), the transmission of Trypanosoma cruzi infection by transfusion has not been unequivocally documented in the United States. We report a case of severe acute transfusion-acquired Chagas disease in a child with Hodgkin disease who had never travelled to an endemic area; however, she had received platelets from an asymptomatic Bolivian immigrant who had serologic evidence of T. cruzi infection.An 11-year-old white girl with Hodgkin disease who had been in remission since May 1987 after splenectomy, radiotherapy, and chemotherapy presented in April 1988 with a temperature of 38.3 °C. Her physical examination...References1. Schmunis G. Chagas' disease and blood transfusion. 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O'Reilly, MD; Donald Armstrong, MDAffiliations: From Memorial Sloan-Kettering Cancer Center and Cornell University Medical College, New York, New York; and Albert Einstein College of Medicine, Bronx, New York. For current author addresses, see end of text. 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