The Emerging Epidemiology of Hepatitis B Antigen
Authors: C. E. Cherubin, W. Szmuness
Journal: Annals of Internal Medicine (1973)

Editorial Notes1 November 1973The Emerging Epidemiology of Hepatitis B AntigenC. E. CHERUBIN, M.D., W. SZMUNESS, M.D.C. E. CHERUBIN, M.D.Search for more papers by this author, W. SZMUNESS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-79-5-745 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptWhen most of us were medical students, we were taught thatserum hepatitiswas that variety of viral hepatitis having a long incubation period and transmitted solely by blood transfusions and contaminated hypodermic needles. How it survived in the eons before the helpful invention of the hypodermic syringe was a problem left for others to speculate about. It is true that Krugman, Giles and Hammond, in their Willowbrook studies (1), upset this dogma when they isolated two different viral agents that did not confer immunity to one another, the commoner having a short incubation period and the least common, a...References1. KRUGMANGILESHAMMOND SJJ: Infectious hepatitis: evidence for two distinctive clinical, epidemiological, and immunological types of infection. JAMA 200:365-373, 1967 CrossrefMedlineGoogle Scholar2. BLUMBERGGERSTLEYHUNGERFORD BBD: A serum antigen (Australia antigen) in Down's syndrome, leukemia, and hepatitis. Ann Intern Med 66:924-931, 1967 LinkGoogle Scholar3. PRINCEHARGROVESZMUNESS ARW: Immunologic distinction between infectious and serum hepatitis. N Engl J Med 288:987-991, 1970 CrossrefGoogle Scholar4. BARKERSHULMANMURRAY LNR: Transmission of serum hepatitis. JAMA 211:1509-1512, 1970 CrossrefMedlineGoogle Scholar5. CHERUBINPURCELLLANDER CRJ: Acquisition of antibody to hepatitis B antigen in three socioeconomically different medical populations. Lancet 2:149-151, 1972 CrossrefMedlineGoogle Scholar6. SZMUNESSPRINCEBROTMAN WAB: Hepatitis B antigen and antibody in blood donors: an epidemiologic study. J Infect Dis 127:17-25, 1973 CrossrefMedlineGoogle Scholar7. SCHWEITZERWINGMCPEAK IAC: Hepatitis and hepatitis-associated antigen in 56 mother-infant pairs. JAMA 220:1092-1095, 1972 CrossrefMedlineGoogle Scholar8. JEFFRIESJAMESJEFFERISS DWF: Australia (hepatitis-associated) antigen in patients attending a venereal disease clinic. Br Med J 2:455-456, 1973 CrossrefMedlineGoogle Scholar9. FULFORDDANECATTERALL KDR: Australia antigen and antibody among patients attending a clinic for sexually transmitted diseases. Lancet 1:1470-1473, 1973 CrossrefMedlineGoogle Scholar10. ADAMHOLLINGERMELNICK EFJ: Type B hepatitis antigen and antibodies among prostitutes and nuns. A study of possible venereal transmission. J Infect Dis. In press Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByDental care and spread of hepatitis B virus infectionImmune response to hepatitis B surface antigenInfectious diseases: annual review of significant publications.Tolerance to hepatitis B antigen: A hypothesis for its termination with ‘immune - RNA’ 1 November 1973Volume 79, Issue 5Page: 745-746KeywordsAntigensBlood transfusionEpidemiologyHepatitis AHepatitis BImmunity Issue Published: 1 November 1973 PDF DownloadLoading ...