tbuckley/cabot-search huggingface dataset:
Hysteric Hydrophobia, with Delirium Tremens
Authors: J. Wheatcroft
Journal: BMJ (1858)

A PARAGRAPH has recently appeared in several newspapers on the subject of arsenicated wall-papers, containing a statement of which the tendency will be to mislead those who happen not to he well acquainted with the subject.It appears that the Commissioners of Inland Revenue, hav- ing entertained the impression that the green paper with 'Which some of their offices were lined was injurious to health, directed Mr. Phillips, their chemist, to institute an investiga- tion as to whether such papers, as had been alleged by Dr.Halley, were likely to produce a poisonous influence on the system." Mr. Phillips's report, which (as the paragraph states) is printed in the Joutrnzal of the Society of Arts, is perfectly con- clusive in solving this question in the negative."Now this statement, correct no doubt in so far as it has reference to the papers which Mr. Phillips examined, may not equally apply to green papers generally.Mr. Phlillips rightly states that the degree of heat which would be necessary to volatilise arsenic would be humanly in- supportable, and consequently arsenic is not likely to be libe- rated by this agency in apartments wherein human beings dwell.It is obviously not by this means, therefore, that ar- senicated papers prove deleterious.Mr. Phillips admits that particles may be separated in the process of cleansing by means of brushes where the glazing is imperfect.In truth, arsenicated papers which are perfectly smooth and properly glazed are probably harmless.But it is altogether different with the tufted or flock papers, and also with the flat papers which are unglazed.In the autumn and winter of last year, I attended a youth labouring under symptoms of arsenical poisoning, viz., aphthous ulceration of the gums and tonsils, violent frontal headache, great languor, nausea and occasional vomiting, inappetence, diarrhcea, disturbed sleep.The complaint, mild at its onset, gradually increased in severity, spite of treatment, and at the end of eight or ten weeks, the patient was removed to the country, where he was speedily restored to health.I had repeatedly expressed a suspicion that the symptoms were those of effluvial or other on 29 July
On Diseased Conditions of the Knee-Joint: Which Require Amputation of the Limb, and those Conditions which are Favourable for Excision of the Joint; with an Explanation of the Relative Advantages of Both Operations, as far as can be Ascertained by Cases Properly Authenticated
Authors: W. P. Swain
Journal: BMJ (1866)

ESG- (Environment, Social, and Governance) oriented strategies have become desirable among individual and institutional investors in recent years, corresponding with qualities desired by entrepreneurial employees, investors, and community stakeholders. Consistent with a long-term, value-creating orientation, entrepreneurs forgo immediate rewards and devote enormous resources to advance their vision. It is this group that the author studies. The research concludes that entrepreneurial organizations develop stronger governance traits compared with “typical” companies. Perhaps, in part, because the cause represents more than financial rewards, entrepreneurial owners pursue a more focused perspective shared by key stakeholders. The analytics indicate that an entrepreneur factor exists, and is one of the most significant factors in explaining excess returns. These entrepreneurs also contribute measurable ESG benefits. The author provides a detailed analysis of an Entrepreneur Index, spanning several positive and negative economic cycles that points to a consistent conclusion. The evidence suggests investment managers, especially those interested in ESG, would be wise to partake in an entrepreneur approach. <b>TOPICS:</b>Factors, risk premia, ESG investing
Confusion over GP contract continues
Authors: A. Gulland
Journal: BMJ (2003)

General practitioners trying to work out how much they would earn under the new contract were faced with new difficulties last week when the web tool to calculate their payments was withdrawn.

The BMA was forced to withdraw the “ready reckoner” on their website because it was calculating London weighting for all GPs—not just those in the capital.

The software was released on Tuesday then withdrawn on Wednesday and did not go back onto the website until Friday afternoon. The fiasco will further anger GPs, whose faith in the BMA is faltering. The BMA was forced to abandon the …
CHRONIC OMEGA 3 POLYUNSATURATED FATTY ACID SUPPLEMENTATION IN HUMANS ATTENUATES ATRIAL MECHANICAL STUNNING AFTER TERMINATION OF ATRIAL ARRHYTHMIAS: REVERSAL OF TACHYCARDIA MEDIATED ATRIAL CARDIOMYOPATHY WITH FISH OILS
Authors: Saurabh Kumar, Fiona Sutherland, Miriam Wheeler, John Morgan, Paul Sparks
Journal: Journal of the American College of Cardiology (2011)
The Narcotic Drug Diseases and Allied Ailments.
Authors: George Eugene Pettey
Journal: JAMA (1913)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Idiopathic Pulmonary Fibrosis
Authors: Ronald G. Crystal, Jack D. Fulmer, William C. Roberts, Morton L. Moss, Bruce R. Line, Herbert Y. Reynolds
Journal: Annals of Internal Medicine (1976)

Idiopathic pulmonary fibrosis is a fatal disorder that starts as an alveolitis and progresses to interstitial fibrosis. Correlative morphologic, physiologic, and biochemical studies in 29 patients have shown that the inflammatory process in best followed by serial bronchoalveolar lavage and 67 Ga citrate scanning, and the fibrotic process is best followed by quantitation of the exercise-induced drop in arterial oxygen tension per unit of oxygen consumed. Although biopsies in idiopathic pulmonary fibrosis seem to show increased amounts of fibrotic tissue, biochemical studies suggest that the disease is probably one of collagen rearrangement rather than collagen increase. Perhaps becasue of this, peripheral lymphocytes of these patients recognize collagen as "non-self" and, when exposed to it in vitro, produce lymphokines and cell lysis. The fibrotic process is probably irreversible, but the inflammatory and immune processes that cause it may be amenable to therapy if diagnosed early.
Potential of vaginal microbicides in HIV control
Authors: A. Stone
Journal: Journal of the Royal Society of Medicine (2004)

The editorial by Professor Kotwal (January 2004 JRSM1) provides a very welcome commentary on South Africa's improved approach to HIV/AIDS. I am surprised, however, that he makes no mention of the potential role of vaginal microbicides in curbing the epidemic. These products are in an advanced stage of development and, like AIDS vaccines, are the subject of clinical trials taking place in several countries, including South Africa. Microbicides are gels containing selected anti-infective agents, for women to insert before sexual intercourse in order to protect themselves and their partners from HIV and other sexually transmitted infections.2 Some 20 microbicides have been successfully tested in human safety studies and several of them are scheduled to begin large-scale field trials this year to find out how well they protect women at high risk of HIV, with the results expected some 3 years later. Unlike condoms, they do not create a physical barrier to reduce sexual pleasure, and—crucially—they are controlled by the woman and will thus make a vital contribution to enhancing women's empowerment.

Microbicides are not intended to replace other vital prevention measures such as those based on health education messages, male and female condoms—or AIDS vaccines when they become available—but will give people a wider choice of potentially life-saving methods of protection.
The Battle Against Heart Disease
Authors: Lester S. King
Journal: JAMA (1971)

The story of heart disease is fascinating for physicians and laymen alike. Indeed, if we study merely the way we acquired our knowledge of the heart—its structure and function, the instruments of precision that made the knowledge possible, the various diseases that gradually got discriminated one from the other, the therapeutic weapons, both medical and surgical—we would really epitomize the entire history of medicine. Dr. Baldry has tried to present such a story, and in large part he has succeeded admirably. The relatively brief text carries us from the ancient Greek philosophers to cardiac transplants, lucidly narrating the high points of man's successful search for knowledge. The presentation effectively combines a chronological account with a topical organization. We learn about the important investigators, the identification of the major diseases, and the remedies that came into being. At the same time we are given a sense of<i>development</i>—the way that
Parental concerns about their child's emotions and behaviour and referral to specialist services: general population survey
Authors: Tamsin Ford, Kapil Sayal, Howard Meltzer, Robert Goodman
Journal: BMJ (2005)

Childhood psychiatric disorders are common and are associated with heavy use of health services.1 Up to a third of children and adolescents attending primary care and paediatric outpatient departments have clinically significant psychopathology.2 3 Only a minority of these children reach specialist mental health services, partly because the presenting complaint is rarely psychological, so their disorders may not be recognised.2 4 Child mental health services may reject inappropriate referrals leading to frustration among referrers and families.

Although medical professionals often depend on parental concerns to identify affected children, we do not know how predictive they are. We used empirical data from the 1999 British child and adolescent mental health survey to examine how predictive parental perceptions of psychological difficulties were of psychiatric disorder and to provide simple strategies to aid clinicians in identifying children requiring referral.1

We used the child benefit register to select a nationally representative sample of 10 438 children aged 5-15 years from Great Britain. The Development and Well Being Assessment combined information from parents, teachers, and young people aged 11 and older to diagnose psychiatric disorders according to …
A Lifecycle Approach to the Evaluation of FDA Approval Methods and Regulatory Actions
Authors: Bruce M. Psaty, Eric M. Meslin, Alasdair Breckenridge
Journal: JAMA (2012)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Female-to-Male Transmission of HIV
Authors: Andrew Phillips
Journal: JAMA (1992)

<h3>To the Editor.</h3> —In their study of female-to-male transmission of HIV, Padian et al<sup>1</sup>draw attention to the considerable methodological difficulties in the design of partner studies, in particular the biases that may lead to overestimation of the risk of transmission and their careful attempts to overcome them. As they discuss, their estimate is lower than many other studies.<sup>1,2</sup>In addition to the issues raised by Padian et al, we suggest that another explanation for the differences could be a methodological problem in their own study that produces a bias toward zero in the estimated transmission rate. The study recruited both men and women infected with HIV and tested the serostatus of their heterosexual partners. For concordantly infected couples, the direction of transmission was ascertained by identifying a "well-established" source of risk for one partner. Overall, 379 couples were reported, 62 of whom were concordantly infected—an "either direction" heterosexual
Editorial: Ice hockey injuries
Authors: H. H. Hussey
Journal: JAMA (1976)

Ice hockey is a graceful, vicious game, especially as it is played by North American professional teams. If anyone doubts the sport's brutality, he failed to see or read about the contest earlier this year between an all-star Russian team and the Philadelphia Flyers. As might be expected with sticks slashing, a puck flying at tremendous speed, fast skating, and rampant body-checking, injuries (many of them serious) are frequent. Like any other body-contact sport, hockey produces its share of fractures, bruises, and damages to vulnerable joints. In addition, there are traumas almost peculiar to hockey, including lacerations of the head and face, punched-out incisor and canine teeth, and ocular injuries. Of the last, Vinger<sup>1</sup>reported ocular injuries suffered by 38 hockey players over a three-year period. From the nature of his report and from his tabulation of age ranges of the injured, it seems evident that he was writing
Treatment of Hypothermia
Authors: David W. Edsall
Journal: JAMA (1980)

<h3>To the Editor.—</h3> The recent article by Frederick S. Southwick, MD, and Preston H. Dalgish, MD (243:1250, 1980), was another of a series of examples of total or near-total recovery from profound hypothermia despite the presence of all signs of death except rigor mortis.<sup>1</sup>The excellent discussion failed to mention one of the more effective, safe, and convenient methods to accomplish core rewarming—the use of overheated humidified ventilation.<sup>2-4</sup>This has been shown not only to prevent but also to reverse mild hypothermia (32 to 34 °C) in the operating room. In my experience, this method is also effective in treating severe hypothermia. To be effective, you must bypass the normal heating or cooling mechanisms of the upper airway via an endotracheal tube. The inspiratory temperature should be close to but not greater than 39 °C.<sup>4</sup>The thermometer must be placed as near to the patient as possible
Wheeze in infancy: protection associated with yeasts in house dust contrasts with increased risk associated with yeasts in indoor air and other fungal taxa
Authors: B. Behbod, J. E. Sordillo, E. B. Hoffman, S. Datta, M. L. Muilenberg, J. A. Scott, G. L. Chew, T. A. E. Platts-Mills, J. Schwartz, H. Burge, D. R. Gold
Journal: Allergy (2013)

Background While fungal exposures are assumed to provoke wheeze through irritant or allergenic mechanisms, little is known about the differential effects of indoor and outdoor fungi on early-life wheeze. Methods In a Boston prospective birth cohort of 499 at-risk infants, culturable fungi in bedroom air and dust and outdoor air were measured at the age of 2–3 months. Wheeze was determined using bimonthly telephone questionnaires. Odds ratios were estimated for an interquartile increase in fungal natural log-transformed concentrations, adjusting for predictors of wheeze and potential confounders. Results Increased odds of 'any wheeze' (≥1 vs 0 episodes) by age one were positively associated with indoor dust Alternaria [odds ratio (OR) = 1.83; 95% confidence interval (CI), 1.07–3.14], Penicillium [OR = 1.18; (0.98–1.43)], and Cladosporium [OR = 1.47; (1.16–1.85)]; indoor air Penicillium [OR = 1.26; (0.92–1.74)]; and outdoor air Cladosporium [OR = 1.68; (1.04–2.72)]. In contrast, indoor dust yeasts were protective [OR = 0.78; (0.66–0.93)]. 'Frequent wheeze' (≥2 vs <2 episodes) by age one was borderline associated with dust yeasts [OR = 0.86; (0.70–1.04)] and indoor air yeasts [OR = 1.53; (0.93–2.53)]. Alternaria concentration was associated with any wheeze for children with maternal mold sensitization [OR = 9.16; (1.37–61.22)], but not for those without maternal mold sensitization [OR = 1.32; (0.79–2.20)]. Conclusions While wheeze rates were higher with exposures to fungal taxa considered to be irritant or allergenic in sensitive subjects, yeasts in the home had a strong protective association with wheeze in infancy. Molecular microbiologic studies may elucidate specific components of innate microbiologic stimulants that lead to contrasting effects on wheeze development.
Significance of parathyroid hormone-related protein as a factor stimulating bone resorption and causing hypercalcemia in myeloma
Authors: Hideki Tsujimura, Fumitaka Nagamura, Tohru Iseki, Shoichiro Kanazawa, Hiromitsu Saisho
Journal: American Journal of Hematology (1998)

Elevated levels of parathyroid hormone-related protein (PTHrP) in hypercalcemic myeloma patients were demonstrated in recent reports, suggesting that PTHrP behaves as a humoral mediator of hypercalcemia in myeloma. Herein we describe a hypercalcemic myeloma patient with a high serum PTHrP level. Moreover, the PTHrP level in the supernatant of bone marrow aspirates was about two-fold of that in serum. Reverve transcriptase-polymerase chain reaction analysis showed PTHrP m-RNA in bone marrow containing myeloma cells. After chemotherapy, the concentrations of calcium and PTHrP decreased and PTHrP mRNA in bone marrow became undetectable. We conclude that PTHrP released by myeloma cells acted as the main bone resorption stimulating factor in this case. Am. J. Hematol. 59:168–170, 1998. © 1998 Wiley-Liss, Inc.
Diffuse Histiocytic Lymphoma
Authors: ED CADMAN
Journal: Annals of Internal Medicine (1977)

Comments and Correction1 February 1977Diffuse Histiocytic LymphomaED CADMAN, M.D., J. R. BERTINO, M.D.ED CADMAN, M.D., J. R. BERTINO, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-86-2-244 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: At Yale we have treated 30 patients who had stage III or IV diffuse histiocytic lymphoma with a combination of cyclophosphamide, 1.5 g/m2intravenously on Day 1; vincristine, 2 mg intravenously weekly X 3; followed by methotrexate (MTX), 80 to 120 mg/m2intravenously weekly X 8 with leucovorin rescue beginning at 24 h; and cytosine arabinoside (cytarabine), 300 mg/m2intravenously with each MTX dose (COMA). In a few patients the MTX-cytosine arabinoside was given for 3 weeks only. The sequence was repeated three or more times for a total treatment period of 9 months. The median survival...Reference1. BERDCORNOGDORFMAN DJR: Long term remission in diffuse histiocytic lymphoma treated with combination sequential chemotherapy. Cancer 35:1050-1054, 1975 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: School of Medicine Yale University 333 Cedar Street New Haven, CT 06510 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByKlinik der malignen Lymphome 1 February 1977Volume 86, Issue 2Page: 244-245KeywordsComaCyclophosphamideCytosineDiffuse large B-cell lymphomaMethotrexate Issue Published: 1 February 1977 PDF DownloadLoading ...
A Novel Drug-Eluting Stent Coated With an Integrin-Binding Cyclic Arg-Gly-Asp Peptide Inhibits Neointimal Hyperplasia by Recruiting Endothelial Progenitor Cells
Authors: Rüdiger Blindt, Felix Vogt, Irina Astafieva, Christian Fach, Mihail Hristov, Nicole Krott, Berthold Seitz, Aphrodite Kapurniotu, Connie Kwok, Manfred Dewor, Anja-Katrin Bosserhoff, Jürgen Bernhagen, Peter Hanrath, Rainer Hoffmann, Christian Weber
Journal: Journal of the American College of Cardiology (2006)
Radioactive Heaven and Earth: The Health and Environmental Effects of Nuclear Weapons Testing In, On, and Above Earth
Authors: Glyn G. Caldwell
Journal: JAMA (1992)

The express purpose of the commission that authored this book was to describe the costs and effects of nuclear weapons production and testing. A further objective was to make the scientific data accessible to encourage the public to seek government accountability for each production and testing locale. Finally, the authors want to focus attention on past environmental damage and adverse health effects, and then urge the public to take action to prevent future harm. The commission has reviewed and reported the number and location of nuclear materials production facilities, weapon construction plants, and testing sites. It attempts to document the political and policy considerations and decisions leading to the selection of the various sites. This is relatively successful with the United States because more information is available about the US nuclear programs as a result of the greater public availability of information through declassification efforts and the Freedom of Information
An evolutionary perspective can help unify disparate accounts of grandparental investment
Authors: Michael Gurven, Eric Schniter
Journal: Behavioral and Brain Sciences (2010)

Abstract Coall &amp; Hertwig (C&amp;H) bring attention to alternative accounts of grandparental investment from economics, evolutionary anthropology, psychology, and sociology, which have yet to be reconciled. We attempt to help integrate some of the disparate perspectives by expanding the scope of the evolutionary perspective, highlighting some gaps, and discussing problems with the authors' treatment of grandparents in traditional societies.