The Question of Cardiomyopathy in Diabetes Mellitus
Authors: TIMOTHY J. REGAN
Journal: Annals of Internal Medicine (1978)

Editorials1 December 1978The Question of Cardiomyopathy in Diabetes MellitusTIMOTHY J. REGAN, M.D., ALLEN B. WEISSE, M.D.TIMOTHY J. REGAN, M.D.Search for more papers by this author, ALLEN B. WEISSE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-89-6-1000 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptControversy during the past decade on the influence of hypoglycemic agents on mortality in diabetes mellitus has served to focus attention on the diabetic patient's cardiovascular system. A recent report in theBritish Medical Journalhas added support to the view that some patients with diabetes mellitus have myocardial alterations that may result in heart failure as the process develops fully (1). This is of particular interest because the authors indicate that most normotensive persons with long-term diabetes but no clinical evidence of heart disease may have a preclinical abnormality of the left ventricle. With a computerized echocardiographic technique, 14...References1. SANDERSONBROWNRIVELLESEKOHNER JDAE: Diabetic cardiomyopathy? An echocardiographic study of young diabetics. Br Med J 1:404-407, 1978 CrossrefMedlineGoogle Scholar2. AHMEDREGANJAFERINARANG STGR: Preclinical reduction of left ventricular function in diabetes mellitus. Am Heart J 89:153-158, 1975 CrossrefMedlineGoogle Scholar3. SPODICKPIGOTTCHIRIFE DVR: Preclinical cardiac malfunction in chronic alcoholism. Comparison with matched normal controls and with alcoholic cardiomyopathy. N Engl J Med 287:677-680, 1972 CrossrefMedlineGoogle Scholar4. RUBLERSAJADIARAOYEHOLFORD SMMF: Noninvasive estimation of myocardial performance in patients with diabetes. Effect of alcohol administration. Diabetes 27:127-134, 1978 CrossrefMedlineGoogle Scholar5. ZONERAICHZONERAICHRHEE SOJ: Noninvasive evaluation in diabetic patients: systolic time intervals and echocardiography, in Diabetes and the Heart, edited by ZONERAICH S. Springfield, Illinois, Charles C Thomas, 1978, pp. 46-56 Google Scholar6. REGANLYONSAHMEDLEVINSONOLDEWURTELAHMADHAIDER TMSGHMB: Evidence for cardiomyopathy in familial diabetes mellitus. J Clin Invest 60:885-899, 1977 CrossrefGoogle Scholar7. SCHWARTZMITCHELL CJ: The relation between myocardial lesions and coronary artery disease. Br Heart J 24:761-786, 1962 CrossrefMedlineGoogle Scholar8. BUJAKHOIROBERTS LNW: Clinically significant cardiac amyloidois. Clinicopathologic finding in 15 patients. Am J Cardiol 26:394-405, 1970 CrossrefMedlineGoogle Scholar9. CRALLROBERTS FW: The extramural and intramural coronary arteries in juvenile diabetes mellitus. Analysis of nine necropsy patients aged 19 to 38 years with onset of diabetes before age 15 years. Am J Med 64:221-230, 1978 CrossrefMedlineGoogle Scholar10. LEDET T: Diabetic cardiopathy: Quantitative histologic studies of the heart from young juvenile diabetics. Acta Pathol Microbiol Scand [A] 84:421-428, 1976 MedlineGoogle Scholar11. GARCIAMCNAMARAGORDONKANNELL MPTW: Morbidity and mortality in diabetics in the Framingham population. Sixteen year follow-up study. Diabetes 23:105-111, 1974 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: College of Medicine and Dentistry of New Jersey Newark, New Jersey PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byCardiomyopathyMetabolic and morphological changes of the heart in Chinese hamsters (CHAD strain) with spontaneous long-term diabetesDiabetes and atherosclerosis: An epidemiologic viewCardiac function and coronary arteriography in asymptomatic Type 1 (insulin-dependent) diabetic patients: Evidence for a specific diabetic heart diseaseDiabetic Cardiomyopathy: The Available EvidencePrevalence of coronary heart disease, left ventricular failure and hypertension in middle-aged, newly diagnosed Type 2 (non-insulin-dependent) diabetic subjectsDEFECTIVE ENERGY METABOLISM OF THE HEART IN DIABETESExercise-induced left ventricular dysfunction in young men with asymptomatic diabetes mellitus (diabetic cardiomyopathy)Cardiac function during stress testing in long-standing insulin-dependent diabeticsEffect of Correction of Hyperglycemia on Left Ventricular Function in Non-Insulin-Dependent (Type 2) DiabeticsBeta blockade in asymptomatic diabetics with abnormal rest electrocardiogramsDilated Cardiomyopathies of the AdultLa myocardiopathie diabétique: aspects cliniques, hémodynamiques et histopathologiquesNon-invasive assessment of left ventricular function in diabetics without clinical heart diseaseClinical and morphological features of human hypertensive-diabetic cardiomyopathy 1 December 1978Volume 89, Issue 6Page: 1000-1002KeywordsCardiomyopathiesCardiovascular therapyComputersDiabetes mellitusHeart failureHypoglycemicsLeft ventricleMortality ePublished: 1 December 2008 Issue Published: 1 December 1978 PDF downloadLoading ...