Hazards of Rapid Administration of Vancomycin
Authors: PHILIPPA NEWFIELD
Journal: Annals of Internal Medicine (1979)

Brief Reports1 October 1979Hazards of Rapid Administration of VancomycinPHILIPPA NEWFIELD, M.D., MICHAEL F. ROIZEN, M.D.PHILIPPA NEWFIELD, M.D.Search for more papers by this author, MICHAEL F. ROIZEN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-91-4-581 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptRecent reviews (1,2) have suggested that 1g of vancomycin be given intravenously immediately before dental procedures, upper respiratory tract surgery, gastrointestinal and genitourinary tract surgery or instrumentation, pelvic examination, dilation and curettage of the uterus, or insertion or removal of an intrauterine device to patients with prosthetic valves or a history of rheumatic fever who cannot receive penicillin. Prophylactic intraoperative administration of vancomycin in neurosurgical patients has also been shown to decrease the incidence of postoperative wound infection, meningitis, cerebritis, and abscess (3).These reviews indicate that the most serious complications of vancomycin administration are ototoxicity and nephrotoxicity in patients...References1. ALEXANDER M. A review of vancomycin after 15 years of use. Drug Intell Clin Pharm. 1974;8:520-5. CrossrefGoogle Scholar2. COOKFARRAR FW. Vancomycin revisited. Ann Intern Med. 1978;88:813-8. LinkGoogle Scholar3. SAVITZMALISMEYERS MLB. Prophylactic antibiotics in neurosurgery. Surg Neurol. 1974;2:95-100. MedlineGoogle Scholar4. GERACIHEILMANNICHOLSWELLMAN JFDW. Antibiotic therapy of bacterial endocarditis: VII. Vancomycin for acute micrococcal endocarditis. Proc Staff Meetings Mayo Clin. 1958; 33:172-81. MedlineGoogle Scholar5. APPELNEU GH. The nephrotoxicity of antimicrobial agents: II. N Engl J Med. 1977;296:722-8. CrossrefMedlineGoogle Scholar6. ROTHENBERG H. Anaphylactoid reaction to vancomycin. JAMA. 1959;171:1101-2. CrossrefMedlineGoogle Scholar7. MILLERTAUSK RH. Anaphylactoid reaction to vancomycin during anesthesia: a case report. Anesth Analg (Cleve). 1977;56:870-2. MedlineGoogle Scholar8. WOODLEYHALL DW. The treatment of severe staphylococcal infections with vancomycin. Ann Intern Med. 1961;55:235-49. LinkGoogle Scholar9. COHENWECHSLERMITCHELLGLICK LAJG. Depression of cardiac function by streptomycin and other antimicrobial agents. Am J Cardiol. 1970;26:505-11. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: PHILIPPA NEWFIELD, M.D.; MICHAEL F. ROIZEN, M.D.Affiliations: University of California School of Medicine San Francisco, California PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byA typical case had rare immediate and delayed red man syndrome multiple times after norvancomycin injection: A case reportRoad Less Traveled: Drug Hypersensitivity to Fluoroquinolones, Vancomycin, Tetracyclines, and MacrolidesImpact of Reduced Preincision Antibiotic Infusion Time on Surgical Site Infection RatesVancomycin-Induced Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Masquerading as Elusive SepsisAcute and Chronic UrticariaAcute and Chronic UrticariaOther Antibiotic AllergyVancomycinCirculatory collapse after topical application of vancomycin powder during spine surgeryHypersensitivity reactions to non beta-lactam antimicrobial agents, a statement of the WAO special committee on drug allergyPulse-spray Treatment of Total Occlusive Jugular Venous Suppurative ThrombophlebitisThe diagnosis and management of anaphylaxis practice parameter: 2010 UpdateANTIBACTERIAL DRUGSStridor accompanying red man's syndrome following perioperative administration of vancomycinIncidence of Vancomycin-Induced Red Man Syndrome in a Women's and Children's HospitalPeri-anesthetic AnaphylaxisPerioperative antibiotic prophylaxis in paediatric cardiac surgeryVancomycinVancomycin Reaction during Spinal AnaesthesiaDesensitization Protocols for Vancomycin HypersensitivityNew anti–Gram-positive agentsExamination of Factors Affecting Efficacy and Adverse Effect, for the Retrospective Study of Vancomycin Hydrochloride (VCM)PRINCIPLES AND PRACTICE OF ANTIBIOTIC THERAPYLife-Threatening Reaction to Vancomycin Given for Noninfectious FeverAntihistamine prophylaxis permits rapid vancomycin infusionOral Antihistamines Reduce the Side Effects from Rapid Vancomycin InfusionOral Antihistamines Reduce the Side Effects from Rapid Vancomycin InfusionComparative safety of teicoplanin and vancomycinVancomycine et arrêt cardiorespiratoire chez le nourrissonPopulation Pharmacokinetics of Vancomycin in Japanese Adult PatientsVancomycin-resistant Enterococcus raffinosus: Molecular epidemiology, species identification error, and frequency of occurrence in a national resistance surveillance programThe perioperative use of ceftriaxone as infection prophylaxis in neurosurgeryEffect of vancomycin infusion on cardiac function in patients scheduled for cardiac operationVancomycin hypersensitivity: Synergism with narcotics and ″desensitization” by a rapid continuous intravenous protocolComparative prophylactic efficacies of ciprofloxacin, ofloxacin, cefazolin, and vancomycin in experimental model of staphylococcal wound infectionComparative study of cefazolin, cefamandole, and vancomycin for surgical prophylaxis in cardiac and vascular operationsAbsence of "red man syndrome" in patients being treated with vancomycin or high-dose teicoplaninReferencesAdverse reactions to vancomycin prophylaxis in cardiac surgeryDiabetic Foot InfectionsConventional and Nonconventional Modes of Vancomycin Administration to Decontaminate the Internal Surface of Catheters Colonized with Coagulase-Negative StaphylococciResistance to vancomycin and teicoplanin: an emerging clinical problemVancomycin-induced histamine release and "red man syndrome": comparison of 1- and 2-hour infusionsCardiovascular collapse and refractory bronchospasm following administration of vancomycin, esmolol, and heparinAntibiotic TherapyRubber AnaphylaxisSimulation of Vancomycin Peak and Trough Concentrations Using Five Dosing Methods in 37 PatientsAnaphylactoid reaction to vancomycin: Report of a caseAn investigation of the cardiotoxic action of vancomycin in the isolated working rat heartVancomycin-Associated Exfoliative Dermatitis during Continuous Ambulatory Peritoneal DialysisVancomycin, Ticarcillin, and Amikacin Compared with Ticarcillin-Clavulanate and Amikacin in the Empirical Treatment of Febrile, Neutropenic Children with CancerParesthesia and Back Pain in a Patient Receiving Vancomycin during HemodialysisResults of a randomized trial of vancomycin prophylaxis in craniotomyMethicillin-resistant Staphylococcus aureus: Pediatric PerspectiveVancomycin pharmacokinetics in patients with various degrees of renal functionHemodialysis-related emergencies—part 1Vancomycin: A ReviewVancomycin-associated shock and rash in newborn infantsDrug-induced AsthmaNifedipine and Vancomycin-Associated Red Man SyndromeMonitoring Vancomycin TherapyVancomycin-Induced Neutropenia during Treatment of Osteomyelitis in an OutpatientAdverse Effects of Vancomycin Administered in the Perioperative PeriodVancomycin and the KidneyVancomycin: An UpdateTo the EditorAnaesthesia and allergic drug reactionsThe "Red Man's Syndrome" and Slow Infusion of VancomycinROBIN L. DAVIS, Pharm.D., ARNOLD L. SMITH, M.D., JEFFREY R. KOUP, Pharm.D.REFERENCESMiscellaneous antibioticsAdministration of Antiinfectives in Minimum Volume and Infusion TimesDoes antibiotic prophylaxis at the time of catheter insertion reduce the incidence of catheter-related sepsis in intravenous nutrition?Red-Neck Syndrome with Slow Infusion of VancomycinFetal distress secondary to vancomycin-induced maternal hypotensionADVERSE REACTIONS TO VANCOMYCINVancomycin and Red NecksBRUCE H. ACKERMAN, Pharm.D., ROBERT W. BRADSHER, M.D.Anaphylactoid reactions to vancomycin during anaesthesia: two clinical reportsVancomycin and the Red Man's SyndromeAntimicrobial TherapyCardiac arrest following administration of vancomycinCommentVancomycin—New Uses for an Old DrugAntimicrobial Therapy in Musculoskeletal SurgeryProfound hypotension from rapid vancomycin administration during cardiac operationGastrointestinal instrumentation, bacteraemia, and endocarditis.VancomycinVancomycin and Chronic HypotensionVancomycin Therapy for Methicillin-Resistant Staphylococcus aureusTANIA C. SORRELL, M.B., B.S., M.D., DONALD R. PACKHAM, M.B., B.S., SIVARAJ SHANKER, B.Sc., MARY FOLDES, B.Sc., ROSEMARY MUNRO, M.B., B.S.Chronic HypotensionOther antibiotic drugs 1 October 1979Volume 91, Issue 4Page: 581-581KeywordsDilation and curettageGastrointestinal tractGenitourinary proceduresIntrauterine devicesMeningitisPenicillinRespiratory systemRheumatic feverUterusVancomycin ePublished: 1 December 2008 Issue Published: 1 October 1979 Copyright & Permissions© 1979 American College of PhysiciansPDF downloadLoading ...