Primary Hypochromic Anemia*
Authors: JOHN E. WALKER
Journal: Annals of Internal Medicine (1933)

Article1 May 1933Primary Hypochromic AnemiaIts Importance in Medical and Surgical DiagnosisJOHN E. WALKER, M.D., F.A.C.P.JOHN E. WALKER, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-6-11-1434 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptHypochromic anemia in adults is generally considered as secondary to some other disease process, such as hemorrhage, malignancy, infection, or nephritis. This view has prevailed so long that "hypochromic anemia" and "secondary anemia" are often used as synonymous terms. In recent years, however, a type of hypochromic anemia has been recognized as an independent disease. The condition may be referred to as primary hypochromic anemia. It occurs almost exclusively in women. Achlorhydria is nearly always present. One of the most characteristic features of the disease is a rapid, almost dramatic, response to iron therapy in massive doses. Its recognition is...References1 NAEGLI O: Blutkrankheiten und Blutdiagnostik: Lehrbuch der klinischen Hämatologie, 5th ed., 1931, J. Springer, Berlin. CrossrefGoogle Scholar2 FABER K: Anämische Zustande bei der chronischen Achylia gastrica, Berl. klin. Wchnschr., 1913, l, 958. Google Scholar3 KAZNELSONREIMANNWEINER PFW: Achylische Chloranämie, Klin. Wchnschr., 1929, viii, 1071-1074. CrossrefGoogle Scholar4 ALTSCHULLER G: Sur le pathogénie de l'anémie hypochrome chronique, dite achylique à propos d'une observation personnelle, Acta med. Scandinav., 1929, lxx, 119-138. Google Scholar5 MCCANNDYE WSJ: Chlorotic anemia with achlorhydria, splenomegaly, and small corpuscular diameters, ANN. INT. MED., 1931, iv, 918-930. Google Scholar6 SCHULTEN H: Zur Behandlung hypochromer Anämien mit maximalen Eisendosen, Münch. med. Wchnschr., 1930, lxxii, 355-356. Google Scholar7 SCHULTEN H: Über die essentielle hypochrome Anämie (achylische Chloranämie) und ihre Beziehungen zur perniziösen Anämie, Münch. med. Wchnschr., 1932, lxxix, 665-667. Google Scholar8 WAUGH TR: Hypochromic anemia with achlorhydria, Arch. Int. Med., 1931, xlvii, 71-81. CrossrefGoogle Scholar9 MILLS ES: Idiopathic hypochromemia, Am. Jr. Med. Sci., 1931, clxxxii, 554-565. CrossrefGoogle Scholar10 WATKINS CH: A classification of chronic idiopathic secondary anemia, with special reference to morphology of blood, Jr. Am. Med. Assoc., 1929, xciii, 1365-1367. CrossrefGoogle Scholar11 METTIERMINOT SRGR: The effect of iron on blood formation as influenced by changing the acidity of the gastroduodenal contents in certain cases of anemia, Am. Jr. Med. Sci., 1931, clxxxi, 25-36. CrossrefGoogle Scholar12 WITTS LJ: Chronic microcytic anemia, Brit. Med. Jr., 1931, ii, 883, 888. CrossrefGoogle Scholar13 DAMESHEK W: Primary hypochromic anemia (erythro-normoblastic anemia); a new type of idiopathic anemia, Am. Jr. Med. Sci., 1931, clxxxii, 520-553. CrossrefGoogle Scholar14 ROSENOW G: Blutkrankheiten, 1925, Julius Springer, Berlin. CrossrefGoogle Scholar15 STRAUSS MB: Chlorotic anemia of pregnancy, report of 3 cases, Am. Jr. Med. Sci., 1930, clxxx, 818-823. CrossrefGoogle Scholar16 MINOTCASTLE GRWB: The adequate treatment of anemia, ANN. INT. MED., 1931, v, 159-169. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Opelika, Alabama*Received for publication September 29, 1932. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 May 1933Volume 6, Issue 11Page: 1434-1440KeywordsAchlorhydriaAnemiaHemorrhageInfectious diseasesNephritis Issue Published: 1 May 1933 PDF downloadLoading ...