Indirect Fluorescent Antibody and Serum Neutralization Response in Pre-exposure Prophylaxis Against Rabies
Authors: SUSANNE E. LARSH
Journal: Annals of Internal Medicine (1965)

Article1 December 1965Indirect Fluorescent Antibody and Serum Neutralization Response in Pre-exposure Prophylaxis Against RabiesSUSANNE E. LARSH, M.D.SUSANNE E. LARSH, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-63-6-955 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptConsiderable experimental work has been done in pre-exposure immunization of humans against rabies in recent years (1-8). However, because human rabies is rare in this country and exposure to it relatively uncommon, knowledge and experience of pre-exposure vaccination have been restricted predominantly to large centers of rabies control and to practitioners of veterinary medicine. Inherent in the procedure is proof of antibody response by the standard serum neutralization test, since some individuals cannot be protected successfully regardless of the immunization schedule and others require more than the usual number of booster doses to provoke detectable serum neutralizing antibodies.Before non-nervous...References1. ANDERSONSCHNURRENBERGERMASTERSONWENTWORTH GRPRRAFH: Avian embryo rabies immunization. I. Duck embryo vaccine administered intradermally in man. Amer. J. Hyg. 71: 158, 1960. MedlineGoogle Scholar2. RUEGSEGGERBLACKSHARPLESS JMJGR: Primary anti-rabies immunization of man with HEP flury virus vaccine. Amer. J. Public Health 51: 706, 1961. CrossrefGoogle Scholar3. SCHNURRENBERGERANDERSONRUSSELLWENTWORTH PRGRJHFH: Avian embryo rabies immunization. II. A comparison of the antigenicity of high egg-passage and duck embryo vaccines administered intradermally in man. Amer. J. Hyg. 74: 1, 1961. MedlineGoogle Scholar4. 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PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAn Indirect Fluorescent Antibody Test for the Serological Detection of Rabies Virus Immunoglobulin G and Immunoglobulin M AntibodiesHuman immune response to rabies nucleocapsid and glycoprotein antigensRabies vaccinesComparison between a modified counterimmunoelectrophoresis test and the indirect fluorescent-antibody test for detection of antibodies to rabies virus in human seraEvaluation of tests for rabies antibody and analysis of serum responses after administration of three different types of rabies vaccinesThe Serum Neutralization, Indirect Fluorescent Antibody, and Rapid Fluorescent Focus Inhibition Tests 1 December 1965Volume 63, Issue 6Page: 955-964KeywordsAllergy and immunologyAntibody productionClinical microbiologyEmbryosMedical servicesPathogenesisPre-exposure prophylaxisRabiesResearch laboratoriesSerology ePublished: 1 December 2008 Issue Published: 1 December 1965 PDF downloadLoading ...