Cytomegalovirus Infection in Previously Healthy Adults
Authors: ERKKI KLEMOLA
Journal: Annals of Internal Medicine (1973)

Editorials1 August 1973Cytomegalovirus Infection in Previously Healthy AdultsERKKI KLEMOLA, M.D.ERKKI KLEMOLA, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-79-2-267 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlthough primary cytomegalovirus infection usually occurs in childhood, serological investigations show that primary infection with this virus or activation of latent infection is common in adults too (1, 2). Most infections in adults are clinically inapparent. In contrast to earlier assumptions, at present there is good evidence that even in previously healthy adults cytomegalovirus infection can occasionally give rise to a great variety of clinical symptoms. In this issue Jordan and others (p. 153) report interesting clinical and laboratory observations on nine patients with "spontaneous" cytomegalovirus mononucleosis, who had no history of pre-illness blood transfusions or surgery. This syndrome, first...References1. WELLER T: The cytomegaloviruses: ubiquitous agents with protean clinical manifestations. N Engl J Med 285:203-214, 267-274, 1971 CrossrefMedlineGoogle Scholar2. KRECHJUNGJUNG UMF: Cytomegalovirus Infections of man. Basel, S. Karger, 1971 Google Scholar3. KLEMOLAKÄÄRIÄINEN EL: Cytomegalovirus as a possible cause of a disease resembling infectious mononucleosis. Br Med J 2:1099-1102, 1965 CrossrefMedlineGoogle Scholar4. STERN H: Isolation of cytomegalovirus and clinical manifestations of infection at different ages. Br Med J 1:665-669, 1968 CrossrefMedlineGoogle Scholar5. CARLSTRÖMALDENBELFRAGE GJS: Acquired cytomegalovirus infection. Br Med J 2:521-525, 1968 CrossrefMedlineGoogle Scholar6. STERNERAGELLWAHREN GBB: Acquired cytomegalovirus infection in older children and adults. Scand J Infect Dis 2:95-103, 1970 CrossrefMedlineGoogle Scholar7. KLEMOLAKÄÄRIÄINENVON ESSEN ELR: Further studies on cytomegalovirus mononucleosis in previously healthy adults. Acta Med Scand 182:311-322, 1967 CrossrefMedlineGoogle Scholar8. KLEMOLAVON ESSENWAGER ERO: Cytomegalovirus mononucleosis in previously healthy individuals. Ann Intern Med 71:11-19, 1969 LinkGoogle Scholar9. KLEMOLASTENSTRÖMVON ESSEN ERR: Pneumonia as a clinical manifestation of cytomegalovirus infection in previously healthy adults. Scand J Infect Dis 4:7-10, 1972 CrossrefMedlineGoogle Scholar10. KLEMOLAVON ESSENHENLE ERG: Infectious-mononucleosis-like disease with negative heterophil agglutination test. Clinical features in relation to Epstein-Barr virus and cytomegalovirus antibodies. J Infect Dis 121:608-614, 1970 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. 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