tbuckley/cabot-search huggingface dataset:
Endocarditis After Lithotripsy
Authors: OLAF C. KRONEMAN
Journal: Annals of Internal Medicine (1987)

Letters and Corrections1 May 1987Endocarditis After LithotripsyOLAF C. KRONEMAN III, M.D., MARC S. BRODSKY, M.D., JAMES MACKENZIE, M.D., ANDREW HAUSER, M.D.OLAF C. KRONEMAN III, M.D., MARC S. BRODSKY, M.D., JAMES MACKENZIE, M.D., ANDREW HAUSER, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-106-5-777_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Extracorporeal shock wave lithotripsy used focused shock waves to disintegrate renal calculi. This technique spares the patient the morbidity of an open surgical procedure. With experience, the complications of this procedure will be better defined. We report the development of endocarditis temporally related to extracorporeal shock wave lithotripsy, a heretofore unreported complication.A 71-year-old man with valvular heart disease was hospitalized with flank pain. A 5-mm calculus was identified in the upper pole of the right kidney. Extracorporeal shock wave lithotripsy was successfully done on 11 December 1985. The patient received trimethoprim and sulfamethoxazole before the procedure....References1. WICKHAMWEBBPAYNEKELLETWATKINSONWHITFIELD JDSMGH. Extracorporeal shock wave lithotripsy: the first 50 patients treated in Britain. Br Med J. 1985;290;1188-9. CrossrefMedlineGoogle Scholar2. CHAUSSYBREMDELSCHMIEDT CWE. Extracorporeally induced destruction of kidney stones by shock waves. Lancet 1980;2:1265-8. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: OLAF C. KRONEMANIII, M.D.; MARC S. BRODSKY, M.D.; JAMES MACKENZIE, M.D.; ANDREW HAUSER, M.D.Affiliations: William Beaumont Hospital Royal Oak, MI 48072 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byEnterococcal endocarditis after extracorporeal shock wave lithotripsy for nephrolithiasis.Risk Factors for Urinary Lithotripsy-Associated SepsisRisk Factors for Urinary Lithotripsy-Associated SepsisRisk of Bacteraemia During Extracorporeal Shock Wave LithotripsyTexte de consensus: Prophylaxie de l'endocardite infectieuseExtracorporeal Shock Wave Lithotripsy of Kidney Stones does not Induce Transient Bacteremia. A Prospective StudySide-effects of extracorporeal piezoelectric shock wave lithotripsy (EPL)Extracorporeal Shock Wave Lithotripsy of a Kidney Stone Complicated with Candida albicans Septicaemia and EndophthalmitisNew Concepts in the Pathogenesis and Modalities of the Chemoprophylaxis of Native Valve Endocarditis 1 May 1987Volume 106, Issue 5Page: 777-777KeywordsCardiovascular therapyEndocarditisExtracorporeal shock wave lithotripsyKidney stonesMorbidityShock ePublished: 1 December 2008 Issue Published: 1 May 1987 PDF downloadLoading ...
Association between incidence of non-Hodgkin's lymphoma and solar ultraviolet radiation in England and Wales
Authors: G. Bentham
Journal: BMJ (1996)

<h3>Abstract</h3> <b>Objectives</b>: To examine whether the incidence of non-Hodgkin9s lymphoma in different areas of England and Wales is associated with levels of solar ultraviolet radiation. <b>Design</b>: Geographically based study examining the association between incidence of non-Hodgkin9s lymphoma and estimated levels of solar ultraviolet radiation, controlling for social class and employment in agriculture. <b>Setting</b>: 59 counties in England and Wales. <b>Subjects</b>: All registered cases of non-Hodgkin9s lymphoma during the period 1968-85. <b>Main outcome measure</b>: Age and sex adjusted odds ratio for non-Hodgkin9s lymphoma in each county. <b>Results</b>: Incidence of non-Hodgkin9s lymphoma was significantly associated with solar ultraviolet radiation levels (P&lt;0.001), even after social class and employment in agriculture were controlled for (P=0.004). In a comparison of counties in the highest and lowest quarters of solar ultraviolet radiation, the relative risk of non-Hodgkin9s lymphoma was 1.27 (95% confidence interval 1.24 to 1.29), rising to 1.34 (1.32 to 1.37) after adjustment for social class and employment in agriculture. <b>Conclusions</b>: The incidence of non-Hodgkin9s lymphoma in different areas of England and Wales is positively associated with levels of solar ultraviolet radiation. These results are consistent with the hypothesis that exposure to solar ultraviolet radiation increases the risk of non-Hodgkin9s lymphoma. <h3>Key messages</h3> Key messages It has been hypothesised that greater exposure of the population to sunlight, which can cause systemic immune suppression, may have contributed to the increase in non-Hodgkin9s lymphoma The geographical pattern of non-Hodgkin9s lymphoma in England and Wales tends to match that of solar ultraviolet radiation Exposure to sunlight may increase the risk of non-Hodgkin9s lymphoma Risks might be reduced by adoption of a more cautious approach to sun exposure
A Common Polymorphism Within MSLN Affects miR-611 Binding Site and Soluble Mesothelin Levels in Healthy People
Authors: Sonia Garritano, Chiara De Santi, Roberto Silvestri, Ombretta Melaiu, Monica Cipollini, Elisa Barone, Marco Lucchi, Roberto Barale, Luciano Mutti, Federica Gemignani, Alessandra Bonotti, Rudy Foddis, Alfonso Cristaudo, Stefano Landi
Journal: Journal of Thoracic Oncology (2014)

Soluble mesothelin related peptide (SMRP) was proposed as a promising diagnostic marker for malignant pleural mesothelioma (MPM). In a previous study, we found that rs1057147 within the 3' untranslated region of MSLN gene was associated with SMRP levels. Thus, we aimed to (1) confirm the previous association on a large series of volunteers and (2) test the hypothesis that the SNP could affect microRNA binding sites.The association analysis was verified in 759 subjects. Then, in silico predictions highlighted miR-611 and miR-887 as candidate miRNAs binding to the polymorphic site. Thus, chimeric constructs bearing the alternative alleles (G > A) were assayed alone or in cotransfection with the miRNA mimics, with dual luciferase reporter assay in non-MPM Met-5A cells. The miRNAs were also assayed by western blot analysis for their ability to down-regulate endogenous mesothelin in the MPM Mero-14 cell line.We confirmed that, among non-MPM volunteers, GG homozygotes have the lowest SMRP levels. When the genotype is taken into account, the specificity of SMRP as biomarker improves from 79.7% to 85.3%. Dual-luciferase assays showed a significantly lower reporter activity when the vector harbored the G allele as compared to A allele. miR-887 mimic caused a reduced reporter activity of vectors harboring A or G alleles, while miR-611 was effective only on the vector harboring the G allele. Transfection of these miRNAs into Mero-14 cells significantly reduced endogenous MSLN protein.SMRP performance as diagnostic biomarker improved by considering the genotype rs1057147. This polymorphism most likely affects a binding site for miR-611.
The rate of sebum excretion in man. A study on the reproducibility and the accuracy of the gravimetric method
Authors: M. CHIVOT, F. ZEZIOLA, J.H. SAURAT
Journal: British Journal of Dermatology (1981)

Journal Article The rate of sebum excretion in man. A study on the reproducibility and the accuracy of the gravimetric method Get access M. CHIVOT, M. CHIVOT Secteur de Recherches de la Clinique Dermatologique de l'Hôpital Saint‐Louis Search for other works by this author on: Oxford Academic Google Scholar F. ZEZIOLA, F. ZEZIOLA Secteur de Recherches de la Clinique Dermatologique de l'Hôpital Saint‐LouisSecteur de Dermatologie Expérimentale, Lab. Path. Exp., C.H.U. Necker‐Enfants‐Malades, 156, rue de Vaugirard, 75730 Paris Cedex 15, France Search for other works by this author on: Oxford Academic Google Scholar J.H. SAURAT J.H. SAURAT Secteur de Recherches de la Clinique Dermatologique de l'Hôpital Saint‐LouisSecteur de Dermatologie Expérimentale, Lab. Path. Exp., C.H.U. Necker‐Enfants‐Malades, 156, rue de Vaugirard, 75730 Paris Cedex 15, France Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 105, Issue 6, 1 December 1981, Pages 701–705, https://doi.org/10.1111/j.1365-2133.1981.tb00981.x Published: 01 December 1981 Article history Accepted: 09 February 1981 Published: 01 December 1981
Neurology for the Non-Neurologist
Authors: Stanford Wessler
Journal: JAMA (1982)

The editors, with the aid of 18 colleagues, have provided a pragmatically organized neurology text to facilitate the needs of primary care physicians. Each of the 23 chapters is concise and clinically oriented, with simple diagrams, relevant questions and answers, and a preselected list of pertinent references for readers wishing more detailed information. The chapters on such commonly met problems as cerebrovascular disease, Parkinson's disease, dementia, and eye signs in neurological diagnosis, for example, should appeal particularly to the busy practitioner.  The text would have been helped in a minor way by a series of diagrams contrasting the sensory defects resulting from upper and lower motor neuron lesions, but the chapter on peripheral nerves is well done. Although admittedly a personal view, I would question the value of this text for medical students.  These minor quibbles aside, the volume should be useful to its primary audience—the active physician who is
Vitamin D Therapy and Cardiac Function in Chronic Kidney Disease
Authors: Sanjay Rajagopalan, Christopher T. Chan
Journal: JAMA (2012)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Exchange Transfusion in the Newborn
Authors: Roy N. Barnett
Journal: JAMA (1963)

<h3>To the Editor:—</h3> When investigators criticize a successful treatment which has saved hundreds of infants (Group O Rh negative blood in exchange transfusion for erythroblastosis fetalis), the evidence adduced should be very convincing (<i>JAMA</i><b>183</b>:523 [Feb 16] 1963). What is their evidence? (1) A statistical study performed by the authors showed no difference in mortality when Group O blood was used for Group O babies as compared with Group O blood used for Group A, B, and AB babies. (2) In vitro studies confirmed the findings of Landsteiner, which are familiar to all, that persons of Group O have anti-A and anti-B antibodies in their blood. (3) In a comparison of two infants, one given group-specific blood in exchange transfusion did better than one given O blood. This is a quite small series for comparison. One notes also that the authors exchange transfused infants with ABO incompatibility at serum
Abstract 4287: Ets-related gene (Erg) expression in developing and adult mouse tissues
Authors: Taduru Sreenath, Shyh-Han Tan, Natallia Mikhalkevich, Sathibalan Ponniah, Valeri Vasioukhin, Charles J. Bieberich, Isabell A. Sesterhenn, Albert Dobi, Shiv Srivastava, Ahmed Mohamed
Journal: Cancer Research (2011)

Abstract Oncogenic activation of the ETS Related Gene (ERG) in human neoplasms was originally identified in subsets of Ewing sarcomas, myeloid leukemias and, recently, in the majority of prostate cancers. Expression of human ERG protein and consequently its functions in normal and disease states needs to be better understood in light of its suggested role in cell differentiation and proliferation. In this study, we analyzed temporal and spatial expression of the Erg protein by immunohistochemical analysis during mouse embryonic and adult organogenesis using a highly specific ERG monoclonal antibody (CPDR ERG-MAb) developed by our group. Initially, we evaluated the specificity of three recently available ERG monoclonal antibodies (Epitomics EPR 3864 and EPR 3863, and CPDR ERG-MAb) using ERG expressing MOLT4, KG1, COLO 320, VCaP tumor cell lines and LNCaP, MCF7, Jurkat cell lines that do not express ERG. Unlike, rabbit monoclonal antibodies to ERG obtained from Epitomics, the ERG MAb did not show cross reactivity to FLI-1 or to the other ETS related proteins. Our comprehensive evaluation of mouse tissues established a widespread immunolocalization of Erg protein in endothelial cells and restricted expression in precartilage and hematopoietic tissues. Intriguingly, Erg is not expressed in any epithelial tissue including prostate epithelium, a common site of tumors with ERG rearrangements and unscheduled ERG expression. Further, use of two different monoclonal antibodies revealed that infiltrating lymphocytes that are occasionally seen in the prostate environment were positive for Fli-1, did not exhibit any Erg expression. These findings will further aid in investigations of Erg functions in normal and disease conditions. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 102nd Annual Meeting of the American Association for Cancer Research; 2011 Apr 2-6; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2011;71(8 Suppl):Abstract nr 4287. doi:10.1158/1538-7445.AM2011-4287
Plasma theophylline concentrations, six minute walking distances, and breathlessness in patients with chronic airflow obstruction.
Authors: W V Evans
Journal: BMJ (1984)

Twenty patients with chronic bronchitis were given incremental dosages of a new slow release preparation of theophylline and observed for its effect on lung function and exercise tolerance. Measurements were made subjectively by using visual analogue scales and objectively using six minute walking distances and spirometry. The study was placebo controlled and had a double blind randomised design. In the dosages used (200, 400, 600, and 800 mg) theophylline produced no significant improvement in forced expiratory volume in one second or forced vital capacity, and there was no overall improvement in peak expiratory flow rate. Similarly, neither effort tolerance nor degree of breathlessness appeared to be influenced by the drug, even when unacceptably high dosages were used. By contrast, placebo yielded a 7% increase in the six minute walking distance. From these results it seems difficult to justify the routine, indiscriminate use of theophylline for chronic bronchitis.
Abstract LB-268: Tumor classification and prediction using the WG-DASL HT Assay in archived sectioned FFPE (AS-FFPE) material
Authors: Craig April, Yujin Hoshida, Jian-Bing Fan
Journal: Cancer Research (2011)

Abstract Formalin-fixed archival tissues represent an invaluable resource for cancer research, since they are widely available and afford correlations of historical clinical data with gene expression signatures thereby facilitating better disease classification and prediction. While FFPE tissue is commonly available in block form, it is also standard practice to archive sectioned slices (AS-FFPE), often at room temperature, which further degrades genetic material due to oxidation. Because of these limitations, gene expression studies using FFPE material are usually performed on material derived from freshly cut blocks and not AS-FFPE samples. Previous mRNA data generated on freshly cut FFPE blocks for two independent liver cancer sample sets yielded gene expression signatures which classified hepatocellular carcinoma (HCC) samples into three subclasses (Cancer Res 2009, 69: 7385) and cirrhotic liver (CL) samples into two (good and poor survival) groups (N Engl J Med 2008, 359:1995). Here, using the WG-DASL HT assay (29K probes), we report on our efforts to use RNA derived from 5-year old AS-FFPE samples that were obtained from a subset of the previously assayed liver cancer sample sets, to generate clinically informative gene expression profiles. With a passing quality control filter of &amp;gt;80% probes detected (p &amp;lt; 0.01) we were able to obtain good quality data for 64/83 (77%) and 37/48 (77%) of the HCC and CL samples, respectively. On average, for the two sample sets, the sample reproducibility across all 29K probe intensities was R2 ∼ 0.85. We next performed prediction analysis using a nearest template prediction method and compared the results with that originally predicted for each of the two sample set. With a confidence threshold of p &amp;lt; 0.05, 38/64 (59%) of the passing HCC samples yielded a prediction with an accuracy of 95% and an error rate of 5%. At the same confidence threshold (p &amp;lt; 0.05), 13/37 (35%) of the passing LC samples yielded a prediction with an accuracy of 69% and an error rate of 31%. Together our results suggest that, despite degradative events such as oxidation and hydrolysis that further fragment archived FFPE sections, gene expression signatures derived from AS-FFPE samples can accurately classify disease states and provide clinically relevant prognoses. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 102nd Annual Meeting of the American Association for Cancer Research; 2011 Apr 2-6; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2011;71(8 Suppl):Abstract nr LB-268. doi:10.1158/1538-7445.AM2011-LB-268
Maternal Cigarette Smoking Is Associated with Increased Inner Airway Wall Thickness in Children Who Die from Sudden Infant Death Syndrome
Authors: JOHN ELLIOT, PETER VULLERMIN, PHILIP ROBINSON
Journal: American Journal of Respiratory and Critical Care Medicine (1998)

The harmful effects of passive cigarette smoke exposure to infants include an increased frequency of asthma exacerbations, lower respiratory viral infections, and the sudden infant death syndrome (SIDS). Because of a difficulty in obtaining airway tissue from infants, little information is available on the effects of passive cigarette smoke exposure on the structure of the infant airway wall. We examined airway dimensions in 19 children who died from SIDS whose mothers smoked more than 20 cigarettes a day prenatally and postnatally, and compared these data with those from 19 infants who died from SIDS and had nonsmoking mothers. Total inner and outer wall areas were calculated for each airway and expressed in terms of the basement membrane perimeter (Pbm). Inner airway wall thickness was greater in the larger airways of those infants whose mothers had smoked more than 20 cigarettes a day. These findings suggest that infants exposed to a high level of passive cigarette smoke develop significant structural changes in their airways. Increased airway wall thickness may contribute to exaggerated airway narrowing and may help explain the previously observed abnormalities in neonatal lung function that have been described in infants of smoking mothers.
Chronic beryllium disease: uncommon disease, less common diagnosis.
Authors: D C Middleton
Journal: Environmental Health Perspectives (1998)

Chronic beryllium disease (CBD) is typically considered only when occupational exposure to beryllium is a certainty; however, CBD has also occurred in occupational and environmental settings where exposure was unexpected. When the etiology of a case of granulomatous pulmonary disease is not determined, sarcoidosis is the "diagnosis of exclusion." This diagnosis does not communicate much information about the patient's prognosis, the disease's etiology, or even what disease etiologies were specifically excluded. Some cases of CBD have been called sarcoidosis, allowing exposure to continue for the patient and (at times) other individuals. The granulomatous changes of sarcoidosis are thought to result from an abnormal immune response. While the etiologic agents that can initiate this response are largely unknown, the immunopathogenesis of CBD has been well described, and laboratory methods are available in a few centers that can (if used) identify beryllium hypersensitivity. The potential for exposure and disease to be widely separated in time and location makes it important for health-care and environmental health professionals to be aware of these new diagnostic methods.
Mechanical ventilation of healthy rats suppresses peripheral immune function
Authors: H.A. Vreugdenhil, C.J. Heijnen, F.B. Plötz, J. Zijlstra, N.J. Jansen, J.J. Haitsma, B. Lachmann, A.J. van Vught
Journal: European Respiratory Journal (2003)

This study was designed to investigate the possible effect of injurious mechanical ventilation on peripheral immune function of healthy rats. Three ventilation strategies were compared: 1) low peak inspiratory pressure (PIP)/positive end-expiratory pressure (PEEP); 2) high PIP/PEEP; and 3) high PIP/zero PEEP (ZEEP). As a reference group, healthy, nonventilated, sham-operated, anaesthetised rats were used. After 4 h, rats were sacrificed and macrophage inflammatory protein (MIP)‐2 levels in lung and plasma were determined. Peripheral immune function was determined by measurement of splenic natural killer (NK) activity, mitogen-induced splenocyte proliferation and in vitro cytokine production. All immune measurements in the low PIP/PEEP group did not differ from the immune measurements in the reference group. High PIP strategies, irrespective of applied PEEP, enhanced MIP‐2 levels in lung and plasma. NK cell activity, mitogen-induced splenocyte proliferation and MIP‐2 and interleukin (IL)‐10 production significantly decreased after high PIP/PEEP ventilation. In the high PIP/ZEEP‐ventilated group, the decrease in splenocyte proliferation, MIP‐2 and IL‐10 production and NK cell activity was more pronounced and interferon‐γ production was also significantly lower than in the low PIP/PEEP group. These data show that high positive inspiratory pressure ventilation induces an inflammatory response in the lung, whereas at the same time the peripheral immune response is downregulated. Ventilator-induced peripheral immune suppression may contribute to poor outcome in acute respiratory distress syndrome patients.
US advertising campaign begins for alternative to sildenafil
Authors: D. Josefson
Journal: BMJ (2003)

The US Food and Drug Administration has just approved vardenafil, a new drug for erectile dysfunction. The drug, to be marketed as Levitra, is to be launched with a high profile advertising campaign using top US sports stars.

The FDA's approval was based on more than 50 trials involving over 5700 men that compared vardenafil with placebo. Men taking vardenafil were on average five times more likely to achieve an erection that sustained intercourse than men taking a placebo, the results of these studies showed. Vardenafil worked …
Bone regeneration using a microstereolithography-produced customized poly(propylene fumarate)/diethyl fumarate photopolymer 3D scaffold incorporating BMP-2 loaded PLGA microspheres
Authors: Jin Woo Lee, Kyung Shin Kang, Seung Ho Lee, Jun-Young Kim, Bu-Kyu Lee, Dong-Woo Cho
Journal: Biomaterials (2010)