Branch Retinal Artery Occlusion after Injection of a Long-Acting Risperidone Preparation
Authors: Johnny Tang, John J. Weiter
Journal: Annals of Internal Medicine (2007)

Letters21 August 2007Branch Retinal Artery Occlusion after Injection of a Long-Acting Risperidone PreparationJohnny Tang, MD and John J. Weiter, MD, PhDJohnny Tang, MDFrom Retina Specialists of Boston, Harvard Medical School, Schepens Eye Research Institute, and the Massachusetts Eye and Ear Infirmary, Cambridge, MA 02140.Search for more papers by this author and John J. Weiter, MD, PhDFrom Retina Specialists of Boston, Harvard Medical School, Schepens Eye Research Institute, and the Massachusetts Eye and Ear Infirmary, Cambridge, MA 02140.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-147-4-200708210-00021 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Background: Adverse events of long-acting risperidone are usually attributed to the drug rather than to its preparation. Microsphere technology used for slow release of risperidone in its long-acting formulation is used for other drugs.Objective: To report a case of branch retinal artery occlusion after injection of long-acting risperidone.Case Report: A 39-year-old man with a history of psychiatric illness presented to our office with blurred vision in his right eye for 3 days after a right buttock injection of long-acting risperidone (Risperdal Consta, Janssen, Titusville, New Jersey). The patient noted the change in vision about 30 minutes after the ...References1. Ereshefsky L, Mannaert E. Pharmacokinetic profile and clinical efficacy of long-acting risperidone: potential benefits of combining an atypical antipsychotic and a new delivery system. Drugs R D. 2005;6:129-37. [PMID: 15869316] CrossrefMedlineGoogle Scholar2. Parellada E. Clinical experience and management considerations with long-acting risperidone. Curr Med Res Opin. 2006;22:241-55. [PMID: 16466596] CrossrefMedlineGoogle Scholar3. Hara H, Virmani R, Ladich E, Mackey-Bojack S, Titus J, Reisman M, et al. Patent foramen ovale: current pathology, pathophysiology, and clinical status. J Am Coll Cardiol. 2005;46:1768-76. [PMID: 16256883] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Retina Specialists of Boston, Harvard Medical School, Schepens Eye Research Institute, and the Massachusetts Eye and Ear Infirmary, Cambridge, MA 02140.Disclosures: None disclosed. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByDopamine dilemma: case report of treating psychosis in patient with retinitis pigmentosaOlanzapine Postinjection Delirium/Sedation Syndrome: An Unrecognized Diagnosis in the Emergency DepartmentOlanzapine long-acting injection: insights from an early case series in the UKPost-injection delirium/sedation syndrome in patients with schizophrenia treated with olanzapine long-acting injection, I: analysis of casesPost-injection delirium/sedation syndrome in patients with schizophrenia treated with olanzapine long-acting injection, II: investigations of mechanismRisperidone long-acting injection as monotherapy and adjunctive therapy in the maintenance treatment of bipolar I disorderCurrent awareness: Pharmacoepidemiology and drug safetyCerebral Ischemia Related to Isotretinoin; Venlafaxine-Induced Alopecia; Cognitive Dysfunction with Tolterodine; Retinal Artery Occlusion after Injection of Long-Acting Risperidone; Olanzapine-Induced Chylomicronemia Presenting as Pancreatitis; Metabolic Effects of the Atypical Antipsychotics – an Editorial; Another Drug-Induced Pancreatitis – This One Caused by a Tyrosine Kinase Inhibitor; Suicide Attempts Related to Antidepressant Medications 21 August 2007Volume 147, Issue 4Page: 283-284KeywordsArteriesConflicts of interestDrugsEdemaIntramuscular injectionsIntraocular pressureLactic acidPatient advocacyVisionVisual acuity ePublished: 21 August 2007 Issue Published: 21 August 2007 CopyrightCopyright © 2007 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...