Anticardiolipin Antibodies and Physical Disability in the Elderly
Authors: Jean-Yves Cesbron
Journal: Annals of Internal Medicine (1997)

Letters15 June 1997Anticardiolipin Antibodies and Physical Disability in the ElderlyJean-Yves Cesbron, MD, Ph Amouyel, MD, PhD, and Eric Masy, MDJean-Yves Cesbron, MDInstitute Pasteur de Lille, 59019 Lille, FranceFaculte de Medecine de Lille, 59019 Lille, FranceSearch for more papers by this author, Ph Amouyel, MD, PhDInstitute Pasteur de Lille, 59019 Lille, FranceFaculte de Medecine de Lille, 59019 Lille, FranceSearch for more papers by this author, and Eric Masy, MDInstitute Pasteur de Lille, 59019 Lille, FranceFaculte de Medecine de Lille, 59019 Lille, FranceSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-126-12-199706150-00024 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Anticardiolipin antibodies (aCL) are associated with an increased risk for vascular thromboses in cerebral, retinal, coronary, and peripheral venous and arterial vessels in young populations [1, 2]. Serum levels of aCL increase significantly with age [3], but the impact of these higher concentrations is largely unknown [4].We addressed this question in a random sample of 1042 French men and women older than 60 years of age [5] who were recruited from the retirement homes in the Nord department (an administrative region of France). For each study participant, disabilities were assessed and classified as “none” (when the ...References1. Shapiro SS. The lupus antigoagulant/antiphospholipid syndrome. Annu Rev Med. 1996; 47:533-53. Google Scholar2. Hughes GR. The antiphospholipid syndrome: ten years on. Lancet. 1993; 342:341-4. Google Scholar3. Mannoussakis MN, Tzioufas AG, Silis AG, Pange PJ, Goudevenous J, Moutsopoulos HM. High prevalence of anticardiolipin antibody and other autoantibodies in healthy population. Clin Exp Immunol. 1987; 69:557-65. Google Scholar4. Tohgi H, Takahashi H, Kashiwaya M, Watanabe K, Hayama K. The anticardiolipin antibody in elderly stroke patients: its effects on stroke types, recurrence, and the coagulation-fibrinolysis system. Acta Neurol Scand. 1994; 90:86-90. Google Scholar5. Amouyel P, Cottel D, Berr C, Vidal O, Brousseau T. ε4 allele of the apolipoprotein E gene is a potent risk factor for cognitive impairment. Neurobiol Aging. 1994; 15:S43. Google Scholar Author, Article, and Disclosure InformationAuthors: Jean-Yves Cesbron, MD; Ph Amouyel, MD, PhD; Eric Masy, MDAffiliations: Institute Pasteur de Lille, 59019 Lille, FranceFaculte de Medecine de Lille, 59019 Lille, France PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAntiphospholipid Syndrome of Late Onset: A Difficult Diagnosis of a Recurrent Embolic StrokeAnticorps antiphospholipides et hémodialyse : une association fréquente corrélée à la thrombose de l’abord vasculaireCognitive dysfunction and white matter abnormalities in antiphospholipid syndromeDISORDERS INVOLVING ABNORMAL COAGULATIONNeurologic manifestations of the antiphospholipid syndromeSyndrome des antiphospholipidesInternational consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS)Cerebral Ischemia in Antiphospholipid SyndromeAntiphospholipid SyndromeIntérêt du dosage des anticorps antinucléaires, des anticorps antiphospholipides et des anticorps anticytoplasme des neutrophiles dans le diagnostic nosologique des rhumatismes inflammatoires chroniques débutant sans signe clinique d’orientationPrevalence and clinical significance of anticardiolipin and anti-β2-glycoprotein-I antibodies in patients with non-Hodgkin's lymphomaNeurologic Manifestations in the Antiphospholipid SyndromeHUGHES (ANTIPHOSPHOLIPID) SYNDROMEImportance des anticorps antiphospholipides en cliniqueAspirine et syndrome des antiphospholipidesCerebral Disease in the Antiphospholipid SyndromePrévalence des anticorps antiphospholipides dans la maladie de Horton et dans la pseudo-polyarthrite rhizoméliqueNeurological manifestations of antiphospholipid antibody syndrome 15 June 1997Volume 126, Issue 12Page: 1003KeywordsAntibodiesAttentionDisabilitiesMini mental state examinationOutpatientsPathogensPopulation statisticsRegression analysisThrombosisVascular diseases ePublished: 15 August 2000 Issue Published: 15 June 1997 Copyright & PermissionsCopyright © 1997 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...