DILANTIN SODIUM: ITS INFLUENCE ON CONDUCT AND ON PSYCHOMETRIC RATINGS OF INSTITUTIONALIZED EPILEPTICS
Authors: Alexander T. Ross, Virginia Jackson
Journal: Annals of Internal Medicine (1940)

Article1 November 1940DILANTIN SODIUM: ITS INFLUENCE ON CONDUCT AND ON PSYCHOMETRIC RATINGS OF INSTITUTIONALIZED EPILEPTICSALEXANDER T. ROSS, M.D., VIRGINIA JACKSONALEXANDER T. ROSS, M.D.Search for more papers by this author, VIRGINIA JACKSONSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-14-5-770 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptReports on the effectiveness of sodium diphenyl hydantoinate (dilantin sodium) in epilepsy have accumulated rapidly since Merritt and Putnam1inaugurated the use of the drug in 1938. Naturally most interest has devolved upon its use in the control of convulsions and upon its toxic effects—rash, anorexia, nausea, vomiting, ataxia, gingivitis,2and to a less extent delusions, hallucinations, prolonged confusion, agitation, depression, irritability, and suspiciousness.3, 4The toxic effects apparently are manifested earlier, more frequently, and more severely in patients over 40 years of age, and consequently the drug would seem to be of less danger in younger and better preserved...References1. MERRITTPUTNAM HHTJ: Sodium diphenyl hydantoinate in the treatment of convulsive disorders, Jr. Am. Med. Assoc., 1938, cxi, 1068. CrossrefGoogle Scholar2. KIMBALL OP: The treatment of epilepsy with sodium diphenyl hydantoinate, Jr. Am. Med. Assoc., 1939, cxii, 1244. CrossrefGoogle Scholar3. BLAIRBAILEYMCGREGOR DKCJS: Treatment of epilepsy with epanutin, Lancet, 1939, ii, 363. CrossrefGoogle Scholar4. FETTERMAN JL: Dilantin sodium therapy in epilepsy, Jr. Am. Med. Assoc., 1940, cxiv, 396. Google Scholar5. DAVIDSONSUTHERLAND SJD: Results with epanutin in mental hospital patients, Brit. Med. Jr., 1939, ii, 720. CrossrefGoogle Scholar6. MCCARTONCARSON WJ: Use of sodium diphenyl hydantoinate, Jr. Ment. Sci., 1939, lxxxv, 965. CrossrefGoogle Scholar7. PHILIPS DP: Epilepsy as a prison problem: its treatment with sodium diphenyl-hydantoinate, Jr. Michigan Med. Soc., 1939, xxxviii, 317. Google Scholar8. HODGSONREESE ERHH: Clinical experience with dilantin in epilepsies, Wisconsin Med. Jr., 1939, xxxviii, 968. Google Scholar9. BLOCK ND: The value of diphenyl hydantoinate in psychoses with convulsive disorders, Psychiatric Quart., 1939, xiii, 711. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Caro, Michigan*Received for publication May 6, 1940.From the Caro State Hospital for Epileptics, R. L. Dixon, M.D., Superintendent. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe Effects of Phenytoin on Impulsive and Premeditated AggressionDiphenylhydantoin and phenobarbital in the relief of psychoneurotic symptomsMental Testing 1 November 1940Volume 14, Issue 5Page: 770-773KeywordsAtaxiaConvulsionsDrug regulationDrugsEpilepsyHallucinationsNauseaPsychometricsSodiumVomiting ePublished: 1 December 2008 Issue Published: 1 November 1940 PDF downloadLoading ...