The Kidney in Cirrhosis
Authors: WILLIAM P. BALDUS
Journal: Annals of Internal Medicine (1964)

Article1 March 1964The Kidney in CirrhosisII. Disorders of Renal FunctionWILLIAM P. BALDUS, M.D., RALPH N. FEICHTER, M.D., WILLIAM H. J. SUMMERSKILL, M.D., JAMES C. HUNT, M.D., KHALIL G. WAKIM, M.D.WILLIAM P. BALDUS, M.D.Search for more papers by this author, RALPH N. FEICHTER, M.D.Search for more papers by this author, WILLIAM H. J. SUMMERSKILL, M.D.Search for more papers by this author, JAMES C. HUNT, M.D.Search for more papers by this author, KHALIL G. WAKIM, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-60-3-366 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptImpairment of renal function, including disorders of water and electrolyte metabolism, may develop spontaneously in patients with hepatic cirrhosis (1-4). The characteristics consist of the insidious development of azotemia progressing to terminal oliguria and hypotension in patients with severe impairment of hepatic function and ascites, who demonstrate neither evidence of primary renal disease nor secondary causes of azotemia (1). Additional clinical and biochemical features have been described, but the mechanisms of impairment of renal function and their relationship to the clinical findings have yet to be established. It has been shown that some patients with cirrhosis may have diminution of...References1. BALDUSFEICHTERSUMMERSKILL WPRNWH: The kidney in cirrhosis. I. Clinical and biochemical features of the azotemia of hepatic failure. Ann. Intern. Med. 60: 000, 1964. LinkGoogle Scholar2. HECKERSHERLOCK RS: Electrolyte and circulatory changes in terminal liver failure. Lancet 2: 1121, 1956. CrossrefGoogle Scholar3. PAPPERBELSKYBLEIFER SJLKH: Renal failure in Laennec's cirrhosis of the liver. I. 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GORNELLANCESTREMEREPAPPERLOWENSTEIN DLRGSLM: Acute changes in renal excretion of water and solute in patients with Laennec's cirrhosis, induced by the administration of the pressor amine, metaraminol. J. Clin. Invest. 41: 594, 1962. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: From the Gastrointestinal Research Unit, Mayo Clinic and Mayo Foundation, Rochester, Minnesota.This investigation was supported in part by research grant AM-06908-01 from the National Institutes of Health, United States Public Health Service, Bethesda, Maryland.Dr. Baldus is a recipient of grant 2A-5259-C1 from the United States Public Health Service, Bethesda, Maryland.Requests for reprints should be addressed to Section of Publications, Mayo Clinic, Rochester, Minnesota. 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MCCLOY, M.D., WILLIAM P. BALDUS, M.D., W. H. J. SUMMERSKILL, D.M., FRANK T. MAHER, M.D., F.A.C.P.Hepatic Failure and the KidneyPartialfunktionen der Niere bei Cirrhosis hepatisRenal failure in patients with cirrhosis of the liverSpontaneous Recovery from the Hepatorenal Syndrome 1 March 1964Volume 60, Issue 3Page: 366-377KeywordsAscitesCirrhosisHypotensionKidneysMannitolMedical servicesPrevention, policy, and public healthRenal diseasesResearch grantsUrea Issue Published: 1 March 1964 PDF downloadLoading ...