Relapse and Reinfection in Acute Pyelonephritis
Authors: THOMAS FEKETE
Journal: Annals of Internal Medicine (1987)

Letters and Corrections1 July 1987Relapse and Reinfection in Acute PyelonephritisTHOMAS FEKETE, M.D., DAVID GARY SMITH, M.D.THOMAS FEKETE, M.D.Search for more papers by this author, DAVID GARY SMITH, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-107-1-114_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editors: In their article comparing the treatment of renal infections with ampicillin or trimethoprim-sulfamethoxazole in 2- or 6-week courses, Stamm and colleagues (1) have blurred the distinction between two very different hypotheses: that longer courses or different antibiotics prevent relapse with the same organism, and that antibiotics prevent reinfections with new organisms during or after antibiotic therapy. We agree that they and others have shown that longer courses can prevent relapse (2). However, we have several questions about their conclusions concerning the prevention of reinfection by antibiotics.First, should both groups have been followed for the same period...References1. STAMM W, MCKEVITT M, and COUNTS G. Acute renal infection in women: treatment with trimethoprim-sulfamethoxazole or ampicillin for two or six weeks. Ann Intern Med. 1987;107:341-5. LinkGoogle Scholar2. TURCK M, ANDERSON K, and PETERSDORF R. Relapse and reinfection in chronic bacteriuria. N Engl J Med. 1966;275:70-3. CrossrefMedlineGoogle Scholar3. KUNIN C. Duration of treatment for urinary tract infections. Am J Med. 1981;71:849-54. CrossrefMedlineGoogle Scholar4. STAMM W, COUNTS G, and WAGNER K. Antimicrobial prophylaxis of recurrent urinary tract infections. Ann Intern Med. 1980;92:770-5. LinkGoogle Scholar1. FIHN S and STAMM W. Interpretation and comparison of treatment studies for uncomplicated urinary tract infections in women. Rev Infect Dis. 1985;7:468-78. CrossrefMedlineGoogle Scholar2. ANDERSON J, GILLESPIE W, and RICHMOND M. Chemotherapy and antibiotic-resistance transfer between Enterobacteria in the human gastrointestinal tract. J Med Microbiol. 1973;6:461-73. CrossrefMedlineGoogle Scholar3. SIGURDSSON J, AHLMEN J, and BERGLUND L. Three day treatment of acute lower urinary tract infection in women: a double blind study with amoxycillin and cotrimazine. Acta Med Scand. 1983;213:55-60. CrossrefMedlineGoogle Scholar4. RONALD A, JAGDIS F, HARDING G, HOBAN S, MUIR P, and GURWITH M. Amoxicillin therapy of acute urinary infections in adults. Antimicrob Agents Chemother. 1977;11:780-4. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: THOMAS FEKETE, M.D.; DAVID GARY SMITH, M.D.Affiliations: Temple University School of Medicine Philadelphia, PA 19140 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 July 1987Volume 107, Issue 1Page: 114-115KeywordsAntibioticsPyelonephritis ePublished: 1 December 2008 Issue Published: 1 July 1987 PDF downloadLoading ...