Apoptosis in Cardiac Myxoma
Authors: Makoto Suzuki, Mareomi Hamada, Kunio Hiwada
Journal: Annals of Internal Medicine (2000)

Letters18 April 2000Apoptosis in Cardiac MyxomaMakoto Suzuki, MD, Mareomi Hamada, MD, and Kunio Hiwada, MDMakoto Suzuki, MDEhime University School of Medicine; Onsen-gun, Ehime, Japan 791-0295 (Suzuki)Ehime University School of Medicine; Onsen-gun, Ehime, Japan 791-0295 (Hamada)Ehime University School of Medicine; Onsen-gun, Ehime, Japan 791-0295 (Hiwada)Search for more papers by this author, Mareomi Hamada, MDEhime University School of Medicine; Onsen-gun, Ehime, Japan 791-0295 (Suzuki)Ehime University School of Medicine; Onsen-gun, Ehime, Japan 791-0295 (Hamada)Ehime University School of Medicine; Onsen-gun, Ehime, Japan 791-0295 (Hiwada)Search for more papers by this author, and Kunio Hiwada, MDEhime University School of Medicine; Onsen-gun, Ehime, Japan 791-0295 (Suzuki)Ehime University School of Medicine; Onsen-gun, Ehime, Japan 791-0295 (Hamada)Ehime University School of Medicine; Onsen-gun, Ehime, Japan 791-0295 (Hiwada)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-132-8-200004180-00028 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Myxoma is well known as a cause of cardiac embolization (1, 2). However, the reason that embolic events frequently occur in patients with cardiac myxoma remains unknown. We report on myxoma cells that were strongly stained by the terminal deoxyribonucleotidyl transferase-mediated dUTP(deoxy uridine 5′-triphosphate)-biotin nick-end labeling (TUNEL) method.A 78-year-old woman was admitted to our hospital because of a right cardiac tumor. She had recently experienced pulmonary embolism and full-body edema. After a 5.5 × 2.8-cm solid mass with lobulated surface was resected from the right atrial septum and was histopathologically diagnosed as cardiac myxoma, TUNEL was ...References1. Silverman J, Olwin JS, Graettinger JS. Cardiac myxoma with systemic embolization. Review of the literature and report of a case. Circulation. 1962;26:99-103. CrossrefMedlineGoogle Scholar2. Reynen K. Cardiac myxomas. N Engl J Med. 1995;333:1610-7. CrossrefMedlineGoogle Scholar3. Ikeda S, Hamada M, Hiwada K. Cardiomyocyte apoptosis with enhanced expression of p53 and bax in right ventricle after pulmonary arterial banding. Life Sci. 1999;65:925-33. CrossrefMedlineGoogle Scholar4. Colucci WS, Schoen FJ, Braunwald E. Primary tumors of the heart. In: Braunwald E, ed. Heart Disease: A Textbook of Cardiovascular Medicine. 5th ed. Philadelphia: WB Saunders; 1997:1464-77. Google Scholar Author, Article, and Disclosure InformationAffiliations: Ehime University School of Medicine; Onsen-gun, Ehime, Japan 791-0295 (Suzuki)Ehime University School of Medicine; Onsen-gun, Ehime, Japan 791-0295 (Hamada)Ehime University School of Medicine; Onsen-gun, Ehime, Japan 791-0295 (Hiwada) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByNovelties in Immunohistochemical and Molecular Study of Cardiac TumorsThe Fas-Mediated Apoptotic Pathway in Cardiac MyxomaTumors of the HeartCaspase-3-dependent apoptosis in cardiac myxoma: not associated with human papillomavirus or Epstein–Barr virusApoptosis in primary cardiac tumoursDisaccharide analysis of glycosaminoglycans synthesized by cardiac myxoma cells in tumor tissues and in cell culture 18 April 2000Volume 132, Issue 8Page: 681KeywordsApoptosisCellsEdemaLight microscopyPulmonary embolismTerminal deoxynucleotidal transferase mediated biotin deoxyuridine triphosphate nick end labelingTransferases Issue Published: 18 April 2000 CopyrightCopyright © 2000 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...