Plasminogen Activator and Cerebral Infarction
Authors: ROBERT E. CRANSTON
Journal: Annals of Internal Medicine (1988)

Letters and Corrections1 May 1988Plasminogen Activator and Cerebral InfarctionROBERT E. CRANSTON, M.D., MARK A. WOLFSON, M.D., HARVEY W. BUCHSBAUM, M.D., WILLIAM M. FEINBERG, M.D., ALAN BARREUTHER, PHARM. D.ROBERT E. CRANSTON, M.D., MARK A. WOLFSON, M.D., HARVEY W. BUCHSBAUM, M.D., WILLIAM M. FEINBERG, M.D., ALAN BARREUTHER, PHARM. D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-108-5-766_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo THE EDITOR: In four series evaluating recombinant tissue plasminogen activator (rTPA) treatment in acute myocardial infarction, no major events of the central nervous system were reported (1, 2). We report the case of a patient with infarction of the right cerebral hemisphere and its probable mechanism after administration of rTPA.A 42-year-old man had chest pain and showed electrocardiographic changes consistent with a diagnosis of anterior wall myocardial infarction. Recombinant tissue plasminogen activator was administered per standard protocol. Acute coronary angiography showed almost total occlusion of the left anterior descending coronary artery, with opening during the procedure and two...References1. DEL ZOPPO G, ZEIMER H, and HARKER L. Thrombolytic therapy in stroke: possibilities and hazards. Stroke. 1986;17:585-607. CrossrefGoogle Scholar2. Tissue type plasminogen activator for acute coronary thrombosis. Med Lett Drugs Ther. 1987;29:1-7-109. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: ROBERT E. CRANSTON, M.D.; MARK A. WOLFSON, M.D.; HARVEY W. BUCHSBAUM, M.D.; WILLIAM M. FEINBERG, M.D.; ALAN BARREUTHER, PHARM. D.Affiliations: Tucson Hospitals Medical Education Program and University of Arizona College of Medicine Tucson, AZ 85712 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byIschemic Cerebral Infarction After rt-PA and Heparin Therapy for Acute Myocardial InfarctionEmbolic Stroke Following Thrombolytic Therapy for Myocardial Infarction in a Patient With Preexisting Ventricular ThrombiThe Risk of Stroke after Thrombolytic TherapyUrgent therapy for stroke. Part I. Pilot study of tissue plasminogen activator administered within 90 minutes.Thrombolytic TherapyIschemic stroke and intracranial hemorrhage following thrombolytic therapy for acute myocardial infarction: A risk-benefit analysisThrombolytic therapy in cerebrovascular disordersIntracerebral hemorrhage, cerebral infarction, and subdural hematoma after acute myocardial infarction and thrombolytic therapy in the Thrombolysis in Myocardial Infarction Study. Thrombolysis in Myocardial Infarction, Phase II, pilot and clinical trial.Stroke complicating thrombolytic therapy of acute myocardial infarctionSystemic Embolization following Thrombolytic Therapy for Acute Myocardial Infarction 1 May 1988Volume 108, Issue 5Page: 766-766KeywordsAngiographyCentral nervous systemCoronary arteriesElectrocardiographyInfarctionIschemiaLeft anterior descending coronary arteryMyocardial infarctionPatient advocacyTissue plasminogen activator ePublished: 1 December 2008 Issue Published: 1 May 1988 PDF downloadLoading ...