Antimalarial Therapy of Lupus Erythematosus
Authors: R. K. Winkelmann, Charles F. Merwin, Louis A. Brunsting
Journal: Annals of Internal Medicine (1961)

Article1 November 1961Antimalarial Therapy of Lupus ErythematosusR. K. WINKELMANN, M.D., CHARLES F. MERWIN, LOUIS A. BRUNSTING, M.D.R. K. WINKELMANN, M.D.Search for more papers by this author, CHARLES F. MERWINSearch for more papers by this author, LOUIS A. BRUNSTING, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-55-5-772 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe treatment of lupus erythematosus with antimalarial compounds has been pursued for almost a decade in this country. In that time, many clinicians have been impressed by the therapeutic efficacy of these drugs. Yet, only one long-term follow-up study (1) is available on which to base a judgment of the value of these drugs. We wish to report data on the results of treatment of lupus erythematosus, both discoid and systemic varieties, seen at the Mayo Clinic, in cases in which quinacrine hydrochloride (Atabrine) therapy was started in 1952 or early in 1953. Early results of treatment in some of...References1. BUCHANAN RN: Quinacrine in the treatment of discoid lupus erythematosus: a 5-year follow up survey—results and evaluation. Southern Med. J. 52: 978, 1959. CrossrefMedlineGoogle Scholar2. KIERLANDBRUNSTINGO'LEARY RRLAPA: Quinacrine hydrochloride (Atabrine) in the treatment of lupus erythematosus. Arch. Derm. 68: 651, 1953. CrossrefGoogle Scholar3. CANNVERHULST HMHL: Fatal acute chloroquine poisoning in children. Pediatrics 27: 95, 1961. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: R. K. WINKELMANN, M.D.; CHARLES F. MERWIN; LOUIS A. BRUNSTING, M.D.Dr. Merwin is on assignment to Mayo Foundation. The contents of this article are the personal views of the Air Force officer and are not to be construed as a statement of official Air Force policy nor as Air Force endorsement of any commercial product described.Requests for reprints should be addressed to Section of Publications, Mayo Clinic, Rochester, Minnesota. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited by80 Meilensteine der Rheumatologie aus 80 Jahren – II: 1961–1980Antipaludéens de synthèseANTIMALARIALS AND IMMUNOSUPPRESSIVE THERAPIESThe efficacy of antimalarials in systemic lupus erythematosusAntimalarial DrugsTREATMENT OF REFRACTORY CUTANEOUS LUPUS ERYTHEMATOSUSANTIMALARIAL AGENTS AND LUPUSThe Efficacy of Antimalarials in Systemic Lupus ErythematosusA Randomized Study of the Effect of Withdrawing Hydroxychloroquine Sulfate in Systemic Lupus ErythematosusEfficacy of antimalarials in systemic lupus erythematosusTreatmentAntimalarials in rheumatology: Efficacy and safetyMiscellanea and raritiesDrug therapy (3): ‘specific’ drugsAnti-malarials in DermatologyAntimalarial Therapy in SLEAntimalarials in the management of discoid and systemic lupus erythematosusCHLOROQUINE: ITS THERAPEUTIC USE IN PHOTOSENSITIVE ERUPTIONSBone Marrow Depression after Drug Therapy in Patients with Systemic Lupus ErythematosusDrugs in DermatologyRheumatism and Arthritis Review of American and English Literature of Recent Years (Sixteenth Rheumatism Review)CHARLEY J. SMYTH, M.D., F.A.C.P., ROGER L. BLACK, M.D., CHARLES CHRISTIAN, M.D., MACK L. CLAYTON, M.D., F.A.C.S., DONALD F. HILL, M.D., F.A.C.P., JOSEPH LEE HOLLANDER, M.D., F.A.C.P., WILLIAM M. MIKKELSEN, M.D., F.A.C.P., MAX M. MONTGOMERY, M.D., F.A.C.P., CARL M. PEARSON, M.D., F.A.C.P., HUGH A. SMYTHE, M.D., F.R.C.P. (C), L. EMMERSON WARD, M.D., F.A.C.P., HOWARD J. WEINBERGER, M.D., F.A.C.P.Lupus ErythematosusSystemic lupus erythematosus and pregnancy 1 November 1961Volume 55, Issue 5Page: 772-776KeywordsAntimalarialsDrugsLupus erythematosusResearch design ePublished: 1 December 2008 Issue Published: 1 November 1961 PDF downloadLoading ...