Latent Cytomegalovirus Infection and Blood Transfusion
Authors: GARY L. KANTOR
Journal: Annals of Internal Medicine (1970)

Editorial Notes1 August 1970Latent Cytomegalovirus Infection and Blood TransfusionGARY L. KANTOR, M.D., B. LAMAR JOHNSON JR., M.D.GARY L. KANTOR, M.D.Search for more papers by this author, B. LAMAR JOHNSON JR., M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-73-2-333 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptRenewed interest in the cytomegalovirus has grown from the recognition that infection with this virus may produce disease in adult patients. Disseminated infection with cytomegalovirus is an increasingly frequent complication in patients with underlying immunologic defects, whether inherited, acquired, or induced by immunosuppressive therapy (1). Fifty to 75% of renal allograft recipients ultimately develop evidence of the infection, and similar involvement occurs in patients with leukemia or lymphoproliferative disorders, particularly after cytotoxic therapy (1, 2). The clinical manifestations are protean although their significance has often been obscured by other pathogenic organisms or manifestations of the underlying disorder (3). Nevertheless, disseminated...References1. WONGWARNER TN: Cytomegalic inclusion disease in adults. Report of 14 cases with review of literature. Arch Path (Chicago) 74:403-422, 1962 MedlineGoogle Scholar2. RIFKINDGOODMANHILL DNR: The clinical significance of cytomegalovirus infection in renal transplant recipients. Ann Intern Med 66:1116-1128, 1967 LinkGoogle Scholar3. KANTORJOHNSON GB: Cytomegalovirus infection associated with cardiopulmonary bypass. Arch Intern Med (Chicago) 125:488-492, 1970 CrossrefMedlineGoogle Scholar4. HEDLEY-WHYTECRAIGHEAD EJ: Generalized cytomegalic inclusion disease after renal homotransplantation. New Eng J Med 272:473-475, 1965 CrossrefMedlineGoogle Scholar5. WYATTHEMSATHSOASH JFM: Disseminated cytomegalic inclusion disease in an adult with primary refractory anemia and transfusional siderosis. Amer J Clin Path 21:50-55, 1951 CrossrefMedlineGoogle Scholar6. KAARIAINENKLEINOLAPALOHEIMO LEJ: Rise of cytomegalovirus antibodies in an infectious-mononucleosis-like syndrome after transfusion. Brit Med J 1:1270-1272, 1966 CrossrefMedlineGoogle Scholar7. LANGSCOLNICKWILLERSON DEJ: Association of cytomegalovirus infection with the post-perfusion syndrome. New Eng J Med 278:1147-1149, 1968 CrossrefMedlineGoogle Scholar8. PALOHEIMOVON ESSENKLEINOLA JRE: Subclinical cytomegalovirus infections and cytomegalovirus mononucleosis after open heart surgery. Amer J Cardiol 22:624-630, 1968 CrossrefMedlineGoogle Scholar9. LANGHANSHAW DJ: Cytomegalovirus infection and the post-perfusion syndrome. New Eng J Med 280:1145-1149, 1969 CrossrefMedlineGoogle Scholar10. STERNELEK HS: The incidence of infection with cytomegalovirus in a normal population: a serological survey in greater London. J Hyg (Camb) 63:79-87, 1965 CrossrefMedlineGoogle Scholar11. EMBILHALDANEMACKENZIE JER: Prevalence of cytomegalovirus infection in a normal urban population in Nova Scotia. Canad Med Ass J 101:730-733, 1969 Google Scholar12. STERN H: Isolation of cytomegalovirus and clinical manifestations of infection at different ages. Brit Med J 1:665-669, 1968 CrossrefMedlineGoogle Scholar13. DIOSIMOLDOVANTOMESAI PEN: Latent cytomegalovirus infection in blood donors. Brit Med J 4:660-662, 1969 CrossrefMedlineGoogle Scholar14. STEVENSBARKERKETCHAUS DLA: Asymptomatic cytomegalovirus infection following blood transfusion in tumor surgery. JAMA 211:1341-1344, 1970 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Nephrology Section Wadsworth General Hospital Department of Medicine UCLA School of Medicine Los Angeles, Calif. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byCYTOMEGALOVIRUS INFECTIONS AFTER OPEN HEART SURGERY 1 August 1970Volume 73, Issue 2Page: 333-334KeywordsBlood transfusionCytomegalovirus infectionImmunosuppressivesInfectious diseasesLymphocytic leukemiaLymphoproliferative disorderPathogens Issue Published: 1 August 1970 PDF downloadLoading ...