Porphyria Cutanea Tarda Remission
Authors: Lori B. Siegel
Journal: Annals of Internal Medicine (1994)

Letters15 August 1994Porphyria Cutanea Tarda RemissionLori B. Siegel, MD and Bridget Barth Eber, PharmDLori B. Siegel, MDSearch for more papers by this author and Bridget Barth Eber, PharmDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-121-4-199408150-00018 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Hepatitis C virus (HCV) has been implicated as a precipitating factor in the expression of porphyria cutanea tarda [1-5]. We describe a patient in whom the syndrome remitted after treatment with α-interferon.A 44-year-old man presented in November 1992 with a 10-year history of hepatitis and an 8-year history of sensitive bullous skin lesions. He denied alcohol consumption. The patient appeared older than his stated age; his facial skin was hyperpigmented and deeply furrowed. Numerous ulcerations and vesicles were present on sun-exposed skin. Areas of hypopigmentation remained where old lesions had healed.Laboratory findings were as follows: ...References1. Fargion S, Piperno A, Cappellini MD, Sampietro M, Fracanzani AL, Romano R, et al. Hepatitis C virus and porphyria cutanea tarda: evidence of a strong association. Hepatology. 1992; 16:1322-6. Google Scholar2. Lacour JP, Bodokh I, Castanet J, Bekri S, Ortonne JP. Porphryia cutanea tarda and antibodies to hepatitis C virus. Br J Derm. 1993; 128:121-3. Google Scholar3. Herrero C, Vincente A, Bruguera M, Ercilla MG, Barrera JM, Vidal J, et al. Is hepatitis C virus infection a trigger of porphyria cutanea tarda? Lancet. 1993; 341:788-9. Google Scholar4. DeCastro M, Sanchez J, Herrera JF, Chaves A, Duran R, Garcia-Buey L, et al. Hepatitis C virus antibodies and liver disease in patients with porphyria cutanea tarda. Hepatology. 1993; 17:551-7. Google Scholar5. Murphy A, Dooly S, Hillary IB, Murphy GM. HCV infection in porphyria cutanea tarda. Lancet. 1993; 341:1534-5. Google Scholar Author, Article, and Disclosure InformationAuthors: Lori B. Siegel, MD; Bridget Barth Eber, PharmD PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byExtrahepatic Manifestations of Hepatitis C Infection: Navigating CHASMCutaneous porphyrias part II: treatment strategiesPorphyria cutanea tarda in an HCV-positive liver transplant patient: a case reportEffective treatment for porphyria cutanea tarda with oral cimetidinePorphyria cutanea tarda as a complication of therapy for chronic hepatitis CDermatologic Disorders Associated With Chronic Hepatitis C: Effect of Interferon TherapyA 32‐Year‐Old Man with Skin LesionsPrevalence of hepatitis C virus infection in porphyria cutanea tarda: systematic review and meta-analysis18 Chronic hepatitis C and porphyria cutanea tardaPorphyria Cutanea Tarda and HIV/AIDS: A Review of Pathogenesis, Clinical Manifestations and ManagementHigh prevalence of hepatitis C virus infection in patients with porphyria cutanea tarda in Poland 15 August 1994Volume 121, Issue 4Page: 308-309KeywordsBiopsyLesionsLiverPhosphatasesPorphyriaResearch laboratoriesSerum glutamic oxaloacetic transaminaseSubcutaneous injectionsUlcersVesicles ePublished: 15 August 2000 Issue Published: 15 August 1994 Copyright & PermissionsCopyright © 1994 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...