The Exocrine Pancreas in Diabetes Mellitus
Authors: JOSEPH B. VACCA
Journal: Annals of Internal Medicine (1964)

Article1 August 1964The Exocrine Pancreas in Diabetes MellitusJOSEPH B. VACCA, M.D., F.A.C.P., WILBERT J. HENKE, M.D., WILLIAM A. KNIGHT JR., M.D., F.A.C.P.JOSEPH B. VACCA, M.D., F.A.C.P., WILBERT J. HENKE, M.D., WILLIAM A. KNIGHT JR., M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-61-2-242 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptStudies of pancreatic exocrine function in patients with diabetes mellitus are few, and the results of these studies are inconclusive. Earlier investigators reported a high incidence of abnormal pancreatic function (1-5); more recently, however, Dreiling (6) and Akton and Klotz (7) noted normal pancreatic exocrine function in uncomplicated diabetes mellitus. This paper reports the results and significance of pancreatic exocrine function tests in a group of patients with diabetes mellitus.MATERIALS AND METHODSFifty-five patients were selected at random from the hospital wards and diabetic clinic. All patients met a minimum requirement of a blood sugar concentration (Folin-Wu) of 140...References1. JONESCASTLEMULHOLLANDBAILEY CMWHF: Pancreatic and hepatic activity in diabetes mellitus. Arch. Intern. Med. (Chicago) 35: 315, 1925. CrossrefGoogle Scholar2. AGRENLAGERLOFBERGLUND GHH: The secretin test of pancreatic function in the diagnosis of pancreatic disease. Acta Med. Scand. 90: 224, 1936. CrossrefGoogle Scholar3. DIAMONDSIEGLE JS: The secretin test in the diagnosis of pancreatic disease with a report of one hundred thirty tests. Amer. J. Dig. Dis. 7: 435, 1940. CrossrefGoogle Scholar4. POLLARDMILLERBREWER HLW: A clinical study of the secretin test. Amer. J. Dig. Dis. 9: 68, 1942. CrossrefGoogle Scholar5. 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CHEYSHAYSHUMAN WYHCR: External pancreatic secretion in diabetes mellitus. Ann. Intern. Med. 59: 812, 1963. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: St. Louis, MissouriFrom the Gastrointestinal Disease Section, Department of Internal Medicine, St. Louis University School of Medicine, and St. Mary's Hospital, St. Louis, Missouri.This investigation was supported in part by a grant from A. H. Robbins Co., Inc., and training grant 2A-5149 from the National Institute of Arthritis and Metabolic Diseases, United States Public Health Service, Bethesda, Maryland.Requests for reprints should be addressed to Joseph B. Vacca, M.D., 3915 Watson Rd., St. Louis 9, Missouri. 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