Reversal of Chronic End-Stage Renal Failure Due to Myeloma Kidney
Authors: Wendy W. Brown, Lee A. Hebert, Walter F. Piering, Anthony V. Pisciotta, Jacob Lemann, John C. Garancis
Journal: Annals of Internal Medicine (1979)

Brief Reports1 May 1979Reversal of Chronic End-Stage Renal Failure Due to Myeloma KidneyWENDY W. BROWN, M.D., LEE A. HEBERT, M.D., WALTER F. PIERING, M.D., ANTHONY V. PISCIOTTA, M.D., JACOB LEMANN Jr., M.D., JOHN C. GARANCIS, M.D.WENDY W. BROWN, M.D.Search for more papers by this author, LEE A. HEBERT, M.D.Search for more papers by this author, WALTER F. PIERING, M.D.Search for more papers by this author, ANTHONY V. PISCIOTTA, M.D.Search for more papers by this author, JACOB LEMANN Jr., M.D.Search for more papers by this author, JOHN C. GARANCIS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-90-5-793 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptRenal insufficiency occurs commonly in multiple myeloma, and its presence has been considered the single most important factor in determining prognosis (1). Renal insufficiency has been attributed to any of these factors: hypercalcemia, hyperuricemia, increased plasma viscosity, intravenous urography (particularly after dehydration), pyelonephritis, amyloidosis, plasma cell infiltration of the kidney, or intratubular precipitation of light chains ("myeloma kidney") (1, 2). Patients with myeloma kidney can recover from acute renal failure. Reversal of chronic end-stage renal failure, however, has not been previously reported.A 61-year-old woman complained of nausea, vomiting, weakness, and fatigue and was hospitalized in her community in August...References1. COHEN H and RUNDLES R: Managing the complications of plasma cell myeloma. Arch Intern Med 135:177-184, 1975 CrossrefMedlineGoogle Scholar2. RANDALL R, WILLIAMSON W, MULLINAX F, TUNG M, and STILL W: Manifestations of systemic light chain deposition. Am J Med 60:293-299, 1976 CrossrefMedlineGoogle Scholar3. LEECH S, POLESKY H, and SHAPIRO F: Chronic hemodialysis in myelomatosis. Ann Intern Med 77:239-242, 1972 LinkGoogle Scholar4. HUMPHREY R, WRIGHT J, ZACHARY J, STERIOFF S, and DEFRONZO R: Renal transplantation in multiple myeloma. A case report. Ann Intern Med 83:651-653, 1975 LinkGoogle Scholar5. KYLE R and ELVEBACK L: Management and prognosis of multiple myeloma. Mayo Clin Proc 51:751-760, 1976 MedlineGoogle Scholar6. CHAVAZ A, MIGNON F, KANFER A, and RICHET G: Traitement de l'insuffisance rénale du myélome multiple par l'hemodialyse chronique. A propos de 4 cas. Nouv Presse Med 5:565-569, 1976 MedlineGoogle Scholar7. TUNG M and RANDALL R: Complications of light chain deposition during chronic hemodialysis (abstract). Clin Res 21:102, 1973 Google Scholar8. VANDENBROUCKE J and VAN YPERSELE C: Traitement par hemodialyse chronique de l'insuffisance rénale terminale sur myélome multiple: survie de 4 ans (abstract). Meeting of the French Society of Nephrology, Louvain, Belgium, 1 February 1975 Google Scholar9. DABIR-VAZIRI N, GOLDMAN R, SCHULTZE R, LEE D, and ROSEN S: Maintenance hemodialysis in myeloma kidney disease. West J Med 126:91-94, 1977 MedlineGoogle Scholar10. MITCH W, WALSER M, BUFFINGTON G, and LEMANN J: A simple method of estimating progression of chronic renal failure. Lancet 2:1326-1328, 1976 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: WENDY W. BROWN, M.D.; LEE A. HEBERT, M.D.; WALTER F. PIERING, M.D.; ANTHONY V. PISCIOTTA, M.D.; JACOB LEMANNJr., M.D.; JOHN C. GARANCIS, M.D.Affiliations: The Medical College of Wisconsin Milwaukee, Wisconsin PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byRenal Disease Is a Prodrome of Multiple Myeloma: An Analysis of 50 Patients from Eastern IndiaManagement of myeloma patients with renal failureThe use of peritoneal dialysis in special situationsPatients with multiple myeloma requiring long-term dialysis: presenting features, response to therapy, and outcome in a series of 20 casesFalse renal failure and chronic renal failureRecovery of Renal Function in Patients on Maintenance DialysisRenal Involvement in DysproteinemiasThe Role of Continuous Ambulatory Peritoneal Dialysis in End-Stage Renal Failure Due to Multiple MyelomaSouthwestern Internal Medicine Conference: Plasma Cell Dyscrasias and the KidneyMultiple myeloma: Current therapy and a glimpse of the futureLight-chain nephropathyDialysis and Transplantation in Multiple MyelomaRenal Involvement in Multiple MyelomaMULTIPLE MYELOMA WITH RENAL FAILURE A CASE FOR INTENSIVE TREATMENTLong-Term Survival of Patients With Multiple Myeloma and Acute Renal Failure at PresentationRegular Dialysis Treatment (RDT)Renal Biopsy Diagnosis of Clinically Silent Multiple MyelomaWAYNE A. BORDER, M.D., ARTHUR H. COHEN, M.D.The plasma cell dyscrasias 1 May 1979Volume 90, Issue 5 Page: 793-794 Keywords Kidneys Myeloma Nausea Patients Plasma cells Pyelography Pyelonephritis Renal failure Research funding Vomiting ePublished: 1 December 2008 Issue Published: 1 May 1979 PDF downloadLoading ...