Fetoprotein from Esophageal Squamous Cell Carcinoma
Authors: JOEL SPRAGINS
Journal: Annals of Internal Medicine (1972)

Letters, Comments, and Corrections1 August 1972Fetoprotein from Esophageal Squamous Cell CarcinomaJOEL SPRAGINS, M.D., W. H. HALL, M.D., H. J. WHITE, M.D.JOEL SPRAGINS, M.D.Search for more papers by this author, W. H. HALL, M.D.Search for more papers by this author, H. J. WHITE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-77-2-322_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: The recent editorials of Gordan and Roof (1) and Kraft (2), "Humors from Tumors," made several points regarding the finding, in patients with malignant neoplasms, of hormones and circulating proteins that are usually characteristic of human fetus ("fetospecific"). One of their points was to anticipate the finding of patients with multiple fetospecific humors.We have observed a case of squamous cell carcinoma of the esophagogastric junction, with undifferentiated metastasis in the liver at autopsy. The patient was found to have alpha-fetoprotein in his serum on two of four occasions by agarose immunodiffusion and to have the fetal...References References1. GORDANROOF GB: "Humors from tumors"; diagnostic potential of peptides. Ann Intern Med 76:501-502, 1972 LinkGoogle Scholar2. KRAFT S: "Humors from tumors": carcinembryonic antigen, alpha-fetoprotein, and digestive system cancer. Ann Intern Med 76:502-504, 1972 LinkGoogle Scholar3. HÄKKINEN I: An immunochemical method for detecting carcinomatous secretion from human gastric juice. Scand J Gastroenterol 1:28-32, 1966 CrossrefMedlineGoogle Scholar4. HÄKKINENKORHONENSAXÉN ILL: The time of appearance and distribution of sulphoglycoprotein antigens in the human foetal alimentary canal. Int J Cancer 3:582-592, 1968 CrossrefMedlineGoogle Scholar5. GITLIN D: Site of alpha fetoprotein synthesis (letter). N Engl J Med 285:1436-1437, 1971 CrossrefMedlineGoogle Scholar1. BERNADESSMADJARUEFF MMB: Présence de l'alpha1-fetoprotéine sérique dans quatre cas de cancers digestifs primitifs autres que l'hépatome. Presse Med 79:1585-1587, 1971 Google Scholar2. ANDRIEUBREARTRODIER JGB: A propos de l'existence de l'alpha1-foeto-protéine en dehors de l'hépatome. Presse Med 79:1595-1596, 1971 Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Little Rock Veterans Administration Hospital and University of Arkansas School of Medicine Little Rock, Ark. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByA Case of Alpha-Fetoprotein Producing Adenocarcinoma of the LungFine-needle aspiration cytology of pulmonary adenocarcinoma of fetal type: Report of a case with lmmunohistochemical and ultrastructural studiesPrimary Adenocarcinoma of the Female Urethra with Three Histologic Patterns and Partial AFP PositivityAlpha-fetoprotein-producing renal cell carcinomaPrimary lung cancer producing alpha-fetoprotein: A case reportOncofetal and Other Tumor-Associated Antigens of the Human Digestive SystemALPHA-FETOPROTEIN AND THE DIAGNOSIS OF LIVER CELL CANCERCarcinofetale AntigeneAlpha-fetoprotein in primary liver cancer and other diseases.The Diagnostic Significance of Serum Alpha-FetoproteinPrimary Liver Cancer, Alpha1 Fetoprotein and Hepatitis B Antigen in Papua New GuineaAlpha-fetorprotein and carcinoembryonic antigen in a case of gastric carcinoma metastatic to the liver 1 August 1972Volume 77, Issue 2Page: 322-323KeywordsAutopsyFetusesHepatocellular carcinomaHormonesProteinsSquamous cell carcinoma Issue Published: 1 August 1972 PDF DownloadLoading ...