Ciprofloxacin and Delirium
Authors: Jordi Altés
Journal: Annals of Internal Medicine (1989)

Letters and Corrections15 January 1989Ciprofloxacin and DeliriumJordi Altés, MD, Joan Gascó, MD, Josep de Antonio, MD, Ana Salas, MD, Concepción Villalonga, MDJordi Altés, MDSearch for more papers by this author, Joan Gascó, MDSearch for more papers by this author, Josep de Antonio, MDSearch for more papers by this author, Ana Salas, MDSearch for more papers by this author, Concepción Villalonga, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-110-2-170_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: The new quinolone antibacterial agents are being increasingly used in many infectious diseases. Their effectiveness and safety seem to make them acceptable, although close surveillance for new adverse effects is encouraged (1).Cases of central nervous system toxicity have been reported in association with norfloxacin (2), enoxacin (3) and pefloxacin (4) treatment. The percentage of adverse reactions of the central nervous system related to ciprofloxacin has been estimated to be 1.6 (1). The more frequently reported central nervous system symptoms were headache, restlessness, tremors, dizziness, and insomnia. Three cases of possibly drug-related hallucinations have been reported (5)....References1. Halkin H. Adverse effects of the fluoroquinolones. Rev Infect Dis. 1988;(Suppl 1):S258-61. CrossrefMedlineGoogle Scholar2. AnastasioMenscerLittle GDJ. Norfloxacin and seizures [Letter]. Ann Intern Med. 1988;109:169-70. LinkGoogle Scholar3. SimpsonBrodie KM. Convulsions related to enoxacin. Lancet. 1985;2:161. CrossrefMedlineGoogle Scholar4. LucetTillyLereboursGresPiguet JHGJH. Neurological toxicity related to Pefloxacin. J Antimicrob Chemother. 1988;21:811-2. CrossrefMedlineGoogle Scholar5. Sanders W. Efficacy, safety, and potential economic benefits of oral ciprofloxacin in the treatment of infections. Rev Infect Dis. 1988;10:528-43. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Hospital Son Dureta Palma de Mallorca Spain PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAcute Delirium Induced by Ciprofloxacin in a Patient With Chronic Kidney DiseaseToolbox: Neuropsychiatric adverse effects of antimicrobial agentsQuinolonesNeurologic Complications in Children with Systemic CancerFluoroquinolone Adverse Effects and Drug InteractionsTopical Review: Acute Neurologic Complications in Children With Systemic CancerEffets secondaires psychiatriques des fluoroquinolonesThe role of ciprofloxacin in a patient with delirium due to multiple etiologiesEffects of ciprofloxacin and enrofloxacin on zoxazolamine kinetics, plasma concentration and sleeping times in micePsychopharmacologic Issues in Organ TransplantationCiprofloxacin-Induced PsychosisOverview of fluoroquinolone safetyPsychopharmacology and neuropsychiatric syndromes in organ transplantationAcute psychoses associated with the use of ciprofloxacin and trimethoprim-sulfamethoxazoleMiscellaneous antibacterial and antiviral drugsPossible interaction of fluoroquinolones with the benzodiazepine-GABAA- receptor complex. 15 January 1989Volume 110, Issue 2Page: 170-171KeywordsAntibioticsCentral nervous systemDeliriumDrugsHallucinationsHeadachesInfectious diseasesInsomniaSafetyToxicity Issue Published: 15 January 1989 PDF downloadLoading ...