Hairy Leukoplakia and the Acquired Immunodeficiency Syndrome
Authors: H. Hollander, D. Greenspan, S. Stringari, J. Greenspan, M. Schiodt
Journal: Annals of Internal Medicine (1986)

Letters and Corrections1 June 1986Hairy Leukoplakia and the Acquired Immunodeficiency SyndromeH. HOLLANDER, M.D., D. GREENSPAN, B.D.S., S. STRINGARI, R.N., J. GREENSPAN, B.D.S., Ph.D., M. SCHIODT, B.D.S.H. HOLLANDER, M.D.Search for more papers by this author, D. GREENSPAN, B.D.S.Search for more papers by this author, S. STRINGARI, R.N.Search for more papers by this author, J. GREENSPAN, B.D.S., Ph.D.Search for more papers by this author, M. SCHIODT, B.D.S.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-104-6-892_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Hairy leukoplakia is a distinctive lesion of the tongue that identifies persons seropositive for the acquired immunodeficiency syndrome (AIDS) virus who are at increased risk of developing frank AIDS (1, 2). The cause of this lesion is thought to be viral, with evidence of both Epstein-Barr virus replication and presence of papillomavirus antigen (3). Because papillomaviruses can be passed sexually and Epstein-Barr virus is found in proximity to other mucosal surfaces, we wondered whether hairy leukoplakia could be found on mucous membranes other than those of the mouth.We studied 19 consecutive homosexual or bisexual men who...References1. GREENSPANGREENSPANCONANTPETERSENSILVERMANDE SOUZA DJMVSY. Oral "hairy" leucoplakia in male homosexuals: evidence of association with both papillomavirus and a herpes-group virus. Lancet. 1984;2:831-4. CrossrefMedlineGoogle Scholar2. . Oral viral lesion (hairy leukoplakia) associated with acquired immunodeficiency syndrome. MMWR. 1985;34:549-50. MedlineGoogle Scholar3. GREENSPANGREENSPANLENNETTE JDE. Replication of Epstein-Barr virus within the epithelial cells of oral "hairy" leukoplakia, an AIDS-associated lesion. N Engl J Me7d. 1985;313:1564-71. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByHairy leukoplakia; lessons learned: 30-plus yearsOral complications of HIV infectionCutaneous manifestations of HIV—a detailed study of morphological variants, markers of advanced disease, and the changing spectrumOral Complications of HIV InfectionImpact of Intensified Dental Care on Outcomes in Human Immunodeficiency Virus InfectionOropharyngeal Lesions in AIDSOral hairy leukoplakia in 71 HIV-seropositive patients: Clinical symptoms, relation to immunologic status, and prognostic significanceOral diseases in HIV-1 infectionORAL HAIRY LEUKOPLAKIASignificance of oral hairy leukoplakiaMucocutaneous Disease in Pediatric Human Immunodeficiency Virus InfectionApproach to gastrointestinal manifestations in infants and children with HIV infectionCutaneous Manifestations of HIV Infection in ChildrenEpidemiology, clinical features and prognostic value of HIV-1 related oral lesionsInfectious Complications in Children with HIV InfectionCutaneous manifestations of HIV infection other than Kaposi's sarcoma: Clinical and histologic aspectsSkin Manifestations of HIV InfectionOral hairy leukoplakia: observations in 95 cases and review of the literatureOral hairy leukoplakia: Diagnosis and managementHairy leucoplakia.Detection of EBV and HPV DNA sequences in oral “hairy” leukoplakia by in situ hybridizationThe Oral Clinical Features of HIV InfectionDiagnosis and Management of the Oral Manifestations of HIV Infection and AIDSBilateral white corrugated lesions on the lateral tongue surfaceAIDS and occlusal traumaAIDS and the oral cavityORAL HAIRY LEUCOPLAKIA IN TWO WOMEN, A HAEMOPHILIAC, AND A TRANSFUSION RECIPIENT 1 June 1986Volume 104, Issue 6Page: 892-892KeywordsAIDSAntigensBisexualsEpstein-Barr virusHomosexualsLesionsMouthMucous membranesTongue Issue Published: 1 June 1986 PDF DownloadLoading ...