Idiopathic Anaphylaxis: A Clinical Summary
Authors: Lee Sonin, Leslie C. Grammer, Paul A. Greenberger, Roy Patterson
Journal: Annals of Internal Medicine (1983)

Brief Reports1 November 1983Idiopathic Anaphylaxis: A Clinical SummaryLEE SONIN, M.D., LESLIE C. GRAMMER, M.D., PAUL A. GREENBERGER, M.D., ROY PATTERSON, M.D.LEE SONIN, M.D.Search for more papers by this author, LESLIE C. GRAMMER, M.D.Search for more papers by this author, PAUL A. GREENBERGER, M.D.Search for more papers by this author, ROY PATTERSON, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-99-5-634 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAnaphylaxis is a systemic, immediate, hypersensitivity reaction that usually occurs because of foods, insect stings, or drugs (1, 2). Exercise-induced anaphylaxis (3) and, recently, food-dependent, exercise-induced anaphylaxis also have been reported (4, 5). Idiopathic anaphylaxis refers to anaphylaxis of unknown cause (6-8). We have studied a group of 50 patients with idiopathic anaphylaxis, including a group of 31 patients previously described by Sale and associates (6). An updated description of the evaluation, treatment, and clinical course of these patients is presented here.Fifty patients with idiopathic anaphylaxis had one or more life-threatening reactions manifested by urticaria or angioedema accompanied by...References1. AUSTEN K. Systemic anaphylaxis in man. JAMA. 1965;192:108-10. CrossrefMedlineGoogle Scholar2. WEISZER I. Allergic emergencies. In: PATTERSON R, ed. Allergic Diseases: Diagnosis and Management. Philadelphia: J.B. Lippincott and Co.; 1980:374-94. Google Scholar3. SHEFFERAUSTEN AK. Exercise-induced anaphylaxis. J Allergy Clin Immunol. 1980;66:106-11. CrossrefMedlineGoogle Scholar4. KIDDCOHENSOSMANFINK JSAJ. Food-dependent exercise-induced anaphylaxis. J Allergy Clin Immunol. 1983;71:407-11. CrossrefMedlineGoogle Scholar5. NOVEYFAIRSHTERSALNESSSIMONCURD HRKRJ. Postprandial exercise-induced anaphylaxis. J Allergy Clin Immunol 1983;71:498-504. CrossrefMedlineGoogle Scholar6. SALEGREENBERGERPATTERSON SPR Idiopathic anaphylactoid reactions. JAMA. 1981;246:2336-9. CrossrefMedlineGoogle Scholar7. BACALPATTERSONZEISS ERC. Evaluation of severe (anaphylactic) reactions. Clin Allergy. 1978;8:295-304. CrossrefMedlineGoogle Scholar8. LIEBERMANTAYLOR PW. Recurrent idiopathic anaphylaxis. Arch Intern Med. 1979;139:1032-4. CrossrefMedlineGoogle Scholar9. MYERSDONLANKALINER GMM. Measurement of urinary histamine: development of methodology and normal value. J Allergy Clin Immunol. 1981;67:305-11. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Northwestern University Medical School Chicago, Illinois PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByThe vascular endothelial specific IL-4 receptor alpha–ABL1 kinase signaling axis regulates the severity of IgE-mediated anaphylactic reactionsBeyond IgE—When Do IgE-Crosslinking and Effector Cell Activation Lead to Clinical Anaphylaxis?Idiopathic AnaphylaxisFood-induced anaphylaxis: mast cells as modulators of anaphylactic severityDiagnostic de l’IgE-réactivité par analyse des composants moléculaires (test ISAC)Autoimmune progesterone dermatitis and its manifestation as anaphylaxis: a case report and literature reviewIdiopathic AnaphylaxisSerum Tryptase in Idiopathic Anaphylaxis: A Case Report and Review of the LiteratureChoc anaphylactique grave avec arrêt cardiaque au café et à la gomme arabique, potentialisé par un collyre bêta-bloquantEmergency medical recognition and management of idiopathic anaphylaxisOutcome of Prophylactic Therapy for Idiopathic AnaphylaxisSansan Wong, MD, Paul R. Yarnold, PhD, Cynthia Yango, MD, Roy Patterson, MD, Kathleen E. Harris, BSAnalysis of plasma histamine levels in patients with mast cell disordersCarcinoid Syndrome and Disorders of Systemic Mast-Cell Activation Including Systemic MastocytosisAnaphylactic shockAnaphylaxisExtrapulmonary Causes of Respiratory FailureAnaphylaxis: Clinical presentation, immunologic mechanisms, and treatmentAlpine Slide Anaphylaxis 1 November 1983Volume 99, Issue 5Page: 634-635KeywordsAnaphylaxisDrugsFoodHypersensitivityInterleukinsMedical servicesUrticaria Issue Published: 1 November 1983 PDF DownloadLoading ...