A Controlled Trial of the Effect of Steroids in Obstructive Airway Disease
Authors: W. K. C. MORGAN
Journal: Annals of Internal Medicine (1964)

Article1 August 1964A Controlled Trial of the Effect of Steroids in Obstructive Airway DiseaseW. K. C. MORGAN, M.D., M.R.C.P.E., E. RUSCHE, M.D.W. K. C. MORGAN, M.D., M.R.C.P.E.Search for more papers by this author, E. RUSCHE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-61-2-248 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptInformed opinion is becoming increasingly aware that there are two main types of obstructive airway disease: asthma and the bronchitis emphysema complex (1). Nevertheless, not infrequently in clinical practice little effort is made to differentiate between them. This error of omission is not always realized, and failure to separate these diseases may lead to unnecessary difficulties in their management. While it is generally accepted that steroids are of benefit in asthma (2-4), some doubt exists as to their efficacy in emphysema, and there would seem little justification in exposing emphysematous patients to potentially harmful and ineffective drugs.There are several...References1. CIBA GUEST SYMPOSIUM: Terminology, definition and classification of chronic pulmonary emphysema and related conditions. Thorax 14: 286, 1959. CrossrefGoogle Scholar2. LUKAS DS: Some effects of ACTH and cortisone on pulmonary function of patients with pulmonary emphysema. Amer. Rev. Tuberc. 64: 279, 1951. Google Scholar3. : Controlled trial of effects of cortisone in chronic asthma. Lancet II: 798, 1956. Google Scholar4. HUMERHYS JONES KME: Bronchodilators and corticosteroids in asthma. Lancet II: 1319, 1960. CrossrefGoogle Scholar5. FRANKLINMICHELSONLOWELLSCHILLER WALFCIW: Bronchodilators and corticosteroids in the treatment of obstructive pulmonary emphysema. New Eng. J. Med. 258: 774, 1958. 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LAWSHEARD JWBE: Emphysema and the chest film: A retrospective radiological and pathological study. Brit. J. Radiol. 35: 750, 1962. CrossrefGoogle Scholar13. DUBOISBOTELHOBEDELLMARSHALLCOMROE ABSYGNRJH: A rapid plethysmographic method for measuring intrathoracic gas volume. J. Clin. Invest. 35: 322, 1956. CrossrefMedlineGoogle Scholar14. DUBOISBOTELHOCOMROE ABSYJH: A new method for measuring airway resistance in men using a body plethysmograph. J. Clin. Invest., 35: 327, 1956. CrossrefMedlineGoogle Scholar15. LLOYDWRIGHT TCGW: Evaluation of methods used in detecting changes in airway resistance in men. Amer. Rev. Resp. Dis. 87: 529, 1963. CrossrefMedlineGoogle Scholar16. LEWINSOHNCAPELSMART HCLMJ: Changes in forced expiratory volumes throughout the day. Brit. Med. J. 1: 462, 1960. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Baltimore, MarylandFrom the University of Maryland School of Medicine, Division for Pulmonary Diseases, Baltimore 1, Maryland.Requests for reprints should be addressed to William K. C. Morgan, M.D., University Hospital, University of Maryland, Redwood and Greene Sts., Baltimore, Maryland 21201. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAstma i toppidretten – fra 1960-årene til i dagOral corticosteroids for stable chronic obstructive pulmonary diseaseSteroid therapy in obstructive airway diseasesCorticosteroids and peptic ulcer: meta-analysis of adverse events during steroid therapyOral Corticosteroid Therapy for Patients with Stable Chronic Obstructive Pulmonary Disease A Meta-AnalysisChristopher M. Callahan, MD, Robert S. Dittus, MD, MPH, Barry P. 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KUNDUR, M.D.Some Effects of Bronchodilators and Corticosteroids in Chronic Obstructive Pulmonary DiseasesThe effect of corticosteroids on methacholine inhalation in symptomatic bronchial asthmaAIRWAYS OBSTRUCTION BEFORE AND AFTER ISOPRENALINE, HISTAMINE, AND PREDNISOLONE IN PATIENTS WITH CHRONIC OBSTRUCTIVE BRONCHITISManagement of patients with cor pulmonale—Acute and chronic 1 August 1964Volume 61, Issue 2Page: 248-254KeywordsAsthmaBronchitisDrugsEmphysemaPreventive medicinePulmonary diseasesRespirationSteroids Issue Published: 1 August 1964 PDF downloadLoading ...