Review of Comparative Effectiveness of Treatments to Prevent Fractures
Authors: Harold Rosen
Journal: Annals of Internal Medicine (2008)

Letters3 June 2008Review of Comparative Effectiveness of Treatments to Prevent FracturesHarold Rosen, MDHarold Rosen, MDFrom Beth Israel Deaconess Medical Center, Boston, MA 02215.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-148-11-200806030-00016 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:I greatly enjoyed the systematic review (1) by MacLean and colleagues on treatments for osteoporosis. However, I disagree with 1 point. Although it is true that they “identified 1 trial on the efficacy of alendronate fracture prevention in patients with renal insufficiency compared with those without renal insufficiency” (2), the authors did not mention another similar analysis documenting the efficacy of risedronate for prevention of fractures in patients with renal insufficiency (3). The article on efficacy of risedronate in patients with chronic kidney disease is especially important, because it documented fracture efficacy of risedronate in patients with ...References1. MacLean C, Newberry S, Maglione M, McMahon M, Ranganath V, Suttorp M, et al. Systematic review: comparative effectiveness of treatments to prevent fractures in men and women with low bone density or osteoporosis. Ann Intern Med. 2008;148:197-213. [PMID: 18087050] LinkGoogle Scholar2. Jamal SA, Bauer DC, Ensrud KE, Cauley JA, Hochberg M, Ishani A, et al. Alendronate treatment in women with normal to severely impaired renal function: an analysis of the fracture intervention trial. J Bone Miner Res. 2007;22:503-8. [PMID: 17243862] CrossrefMedlineGoogle Scholar3. Miller PD, Roux C, Boonen S, Barton IP, Dunlap LE, Burgio DE. Safety and efficacy of risedronate in patients with age-related reduced renal function as estimated by the Cockcroft and Gault method: a pooled analysis of nine clinical trials. J Bone Miner Res. 2005;20:2105-15. [PMID: 16294264] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Beth Israel Deaconess Medical Center, Boston, MA 02215.Disclosures: None disclosed. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoSystematic Review: Comparative Effectiveness of Treatments to Prevent Fractures in Men and Women with Low Bone Density or Osteoporosis Catherine MacLean , Sydne Newberry , Margaret Maglione , Maureen McMahon , Veena Ranganath , Marika Suttorp , Walter Mojica , Martha Timmer , Alicia Alexander , Melissa McNamara , Sheetal B. Desai , Annie Zhou , Susan Chen , Jason Carter , Carlo Tringale , Di Valentine , Breanne Johnsen , and Jennifer Grossman Review of Comparative Effectiveness of Treatments to Prevent Fractures Lionel S. Lim Review of Comparative Effectiveness of Treatments to Prevent Fractures John L. Stock , John L. Mershon , and Michael Jay Schoenfeld Review of Comparative Effectiveness of Treatments to Prevent Fractures Dennis M. Black , Steven Boonen , Pierre Delmas , and Kenneth W. Lyles Review of Comparative Effectiveness of Treatments to Prevent Fractures Robert Karis Review of Comparative Effectiveness of Treatments to Prevent Fractures Catherine MacLean , Margaret Maglione , and Marika Suttorp Metrics 3 June 2008Volume 148, Issue 11Page: 884KeywordsChronic kidney diseaseConflicts of interestGlomerular filtration rateOsteoporosisRenal analysisSystematic reviews ePublished: 3 June 2008 Issue Published: 3 June 2008 CopyrightCopyright © 2008 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...