Cytomegalovirus Viremia with Transmission from Mother to Fetus
Authors: MORRIS L. V. FRENCH
Journal: Annals of Internal Medicine (1977)

Letters1 June 1977Cytomegalovirus Viremia with Transmission from Mother to FetusMORRIS L. V. FRENCH, PH.D., JOSEPH F. THOMPSON, M.D., ARTHUR WHITE, M.D., F.A.C.P.MORRIS L. V. FRENCH, PH.D.Search for more papers by this author, JOSEPH F. THOMPSON, M.D.Search for more papers by this author, ARTHUR WHITE, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-86-6-748 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptCytomegalovirus is a significant cause of mental retardation when infection is acquired in utero. Systemic infection has not been documented previously in the pregnant mother by isolation of cytomegalovirus from blood. We have recently studied a patient with fever with cytomegalovirus cultured from urine and blood. The virus was also cultured from amniotic fluid, placenta, fetal brain, and liver.Freshly voided urine, buffy coat of heparinized blood, and ground tissues were cultured on Rhesus monkey kidney, human embryonic kidney, and WI-38 monolayer tubes. Tissue culture tubes were rotated in a roller drum at 35 °C. The monkey kidney and human...References1. JORDONROUSSEAUSTEWART MWJ: Spontaneous cytomegalovirus mononucleosis. Ann Intern Med 79:153-160, 1973 LinkGoogle Scholar2. HAYESGIBAS KH: Placental cytomegalovirus infection without fetal involvement following primary infection in pregnancy. J Pediatr 79:401-405, 1971 CrossrefMedlineGoogle Scholar3. DAVISTWEEDSTEWART LGJ: Cytomegalovirus mononucleosis in a first trimester pregnant female with transmission to the fetus. Pediatrics 48:200-206, 1971 MedlineGoogle Scholar4. YOWTABER ML: Cytomegalovirus infections in the pregnant female and the newborn infant. Clin Obstet Gynecol 15:993-1003, 1972 CrossrefMedlineGoogle Scholar5. MONIFEGANHELD GEB: The correlation of maternal cytomegalovirus infection during varying stages in gestation with neonatal involvement. J Pediatr 80:17-20, 1972 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Departments of Clinical Pathology, Obstetrics and Gynecology, and Medicine Indiana University School of Medicine Indianapolis, IN 46202 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByCytomegalovirus InfectionsVariation in the pathogenic potential and molecular characteristics of bovid herpesvirus-4 isolatesRole of primary and secondary maternal viremia in transplacental guinea pig cytomegalovirus transferGuinea Pig Cytomegalovirus Gene ExpressionDelayed amplification of cytomegalovirus infection in the placenta and maternal tissues during late gestationThe placenta as a site of cytomegalovirus infection in guinea pigsA prospective study of primary cytomegalovirus infection during pregnancy: final reportEpidemiological Studies of Congenital Cytomegalovirus Infection 1 June 1977Volume 86, Issue 6Page: 748-749KeywordsBloodCytomegalovirus infectionKidneysLiverPlacentaPregnancyRhesusTissue culturesUrineViremia Issue Published: 1 June 1977 PDF DownloadLoading ...