Topical Treatment of Warts and Mollusca with Imiquimod
Authors: Ulrich R. Hengge
Journal: Annals of Internal Medicine (2000)

Letters4 January 2000Topical Treatment of Warts and Mollusca with ImiquimodUlrich R. Hengge, MD, Manfred Goos, MD, and Rüdiger Arndt, MDUlrich R. Hengge, MDUniversity of Essen; 45122 Essen, Germany (Hengge)University of Essen; 45122 Essen, Germany (Goos)Institute of Immunology, Pathology and Molecular Biology; 22339 Hamburg, Germany (Arndt), Manfred Goos, MDUniversity of Essen; 45122 Essen, Germany (Hengge)University of Essen; 45122 Essen, Germany (Goos)Institute of Immunology, Pathology and Molecular Biology; 22339 Hamburg, Germany (Arndt), and Rüdiger Arndt, MDUniversity of Essen; 45122 Essen, Germany (Hengge)University of Essen; 45122 Essen, Germany (Goos)Institute of Immunology, Pathology and Molecular Biology; 22339 Hamburg, Germany (Arndt)Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-132-1-200001040-00024 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Despite numerous therapeutic options, the treatment of common warts and mollusca contagiosa remains unsatisfactory for both patients and physicians. Epidemiologic studies estimate the prevalence of nongenital cutaneous warts at 0.78% to 22%, with a peak occurring in young adolescents (1). The incidence of common warts and mollusca contagiosa is especially high in persons with atopic dermatitis, diabetes, and immunodeficiency (2).Current treatments rely on the ablation of warts or the interruption of cell division (3). Imiquimod, a novel topical immune response modifier, has been successfully used for the treatment of external anogenital warts (4). We evaluated the ...References1. Kilkenny M, Merlin K, Young R, Marks R. The prevalence of common skin conditions in Australian school students: 1. Common, plane and plantar viral warts. Br J Dermatol. 1998;138:840-5. CrossrefMedlineGoogle Scholar2. Tschachler E, Bergstreser PR, Stingl G. HIV-related skin diseases. Lancet. 1996;348:659-63. CrossrefMedlineGoogle Scholar3. Phelps WC, Alexander KA. Antiviral therapy for human papillomaviruses: rationale and prospects. Ann Intern Med. 1995;123:368-82. LinkGoogle Scholar4. Beutner KR, Spruance SI, Hougham AJ, Fox TL, Owens MI, Douglas JM. Treatment of genital warts with an immune-response modifier (imiquimod). J Am Acad Dermatol. 1998;38 2 Pt 1 230-9. CrossrefMedlineGoogle Scholar5. Slade HB, Owens MI, Tomni MA, Miller RI. Imiquimod 5% cream (Aldara). Exp Opin Invest Drugs. 1998;7:437-49. CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: University of Essen; 45122 Essen, Germany (Hengge)University of Essen; 45122 Essen, Germany (Goos)Institute of Immunology, Pathology and Molecular Biology; 22339 Hamburg, Germany (Arndt) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byInterventions for molluscum contagiosum in people infected with human immunodeficiency virus: a systematic reviewEvaluation of serum interleukin-12 and interferon-γ in patients with multiple warts treated with intralesional tuberculin injectionAdjuvant effects of poly I:C and imiquimod on the immunization of kuruma shrimp (Marsupenaeus japonicus) with a recombinant protein, VP28 against white spot syndrome virusUK national guideline for the management of Genital Molluscum in adults, 2014 Clinical Effectiveness Group, British Association for Sexual Health and HIVBritish Association of Dermatologists' guidelines for the management of cutaneous warts 2014InfectionsEfforts to Counteract Locally the Effects of Systemic Immunosupression: A Review on the Use of Imiquimod, a Topical Immunostimulator in Organ Transplant RecipientsChildhood molluscum contagiosumUse of topical immunomodulators in organ transplant recipientsManagement of Cutaneous WartsThe novel synthetic immune response modifier R-848 (Resiquimod) shifts human allergen-specific CD4+ TH2 lymphocytes into IFN-γ–producing cellsSkin Infections and InfestationsImiquimod: Kritische Wertung der möglichen IndikationenImiquimod Does not Affect Shedding of Viable Chlamydiae in a Murine Model of Chlamydia trachomatis Genital Tract InfectionCutaneous diseases of the foot: unapproved treatmentsAntiviral drugs: unapproved uses, dosages, or indicationsTreatment of Human Papilloma Virus in a 6‐Month‐Old Infant with Imiquimod 5% CreamGenitoanale HPV-Infektionen - Imiquimod¿Qué hay de nuevo en terapéutica?Guidelines for the management of cutaneous wartsTreatment of Molluscum Contagiosum with Topical 5% Imiquimod CreamHuman papillomavirus infections in children 4 January 2000Volume 132, Issue 1Page: 95KeywordsErythemaHIVImmune responseImmunodeficienciesLesionsNecrosisPatientsPruritusSafetyWarts Issue Published: 4 January 2000 Copyright & PermissionsCopyright © 2000 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...