Pseudoephedrine Reaction Presenting as Recurrent Toxic Shock Syndrome
Authors: Diana K. Cavanah
Journal: Annals of Internal Medicine (1993)

Brief Reports15 August 1993Pseudoephedrine Reaction Presenting as Recurrent Toxic Shock SyndromeDiana K. Cavanah and Zuhair K. BallasDiana K. CavanahFrom the University of Iowa College of Medicine, Iowa City, Iowa.Search for more papers by this author and Zuhair K. BallasFrom the University of Iowa College of Medicine, Iowa City, Iowa.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-119-4-199308150-00009 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Adverse drug reactions are common and can have many clinical manifestations [1]. Some of these reactions, such as the IgE-mediated reactions and the maculopapular rashes, are readily recognized as drug related. Other reactions, such as aseptic meningitis [2] or myocarditis [3], require a high index of suspicion for a drug-related cause. We describe a patient who had an adverse reaction to pseudoephedrine. Symptoms were the same as those seen in recurrent toxic shock syndrome.Case ReportAn 18-year-old woman was referred for evaluation of a possible immunodeficiency causing recurrent toxic shock syndrome. Her problems began in August 1988 when she ...References1. Van Arsdel PP Jr. Drug reactions: allergy and near-allergy. Ann Allergy. 1986; 57:305-11. Google Scholar2. Ballas ZK, Donta ST. Sulindac-induced aseptic meningitis. Arch Intern Med. 1982; 142:165-6. Google Scholar3. Taliercio CP, Olney BA, Lie JT. Myocarditis related to drug hypersensitivity. Mayo Clin Proc. 1985; 60:463-8. Google Scholar4. Hughes DT, Empey DW, Land M. Effects of pseudoephredrine in man. J Clin Hosp Pharm. 1983; 8:315-21. Google Scholar5. Taylor BJ, Duffill MB. Recurrent pseudo-scarlatina and allergy to pseudoephedrine hydrochloride. Br J Dermatol. 1988; 118:827-9. Google Scholar6. Camisa C. Fixed drug eruption due to pseudoephedrine. Cutis. 1988; 41:339-40. Google Scholar7. Shelly WB, Shelley ED. Nonpigmenting fixed drug eruption as a reaction pattern: examples caused by sensitivity to pseudoephedrine hydrochloride and tetrahydrozoline. J Am Acad Dermatol. 1987; 17:403-7. Google Scholar Author, Article, and Disclosure InformationAuthors: Diana K. Cavanah; Zuhair K. BallasAffiliations: From the University of Iowa College of Medicine, Iowa City, Iowa.Corresponding Author: Zuhair K. Ballas, MD, Department of Internal Medicine, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242-1081.Acknowledgments: The authors thank Gary Beck for editorial and moral support. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byNon-pigmenting fixed drug eruption with mixed features of acute generalized exanthematous pustulosis induced by pseudoephedrine: a case reportAcute generalised exanthematous pustulosis and other severe drug eruptions from over the counter medications: A case report and review of the literatureEphedra, ephedrine, and pseudoephedrineDrug ReactionsExanthematic reaction to pseudoephedrineTOXIC SHOCK SYNDROMEInfections of the Lower Genital TractSevere adverse drug reactions due to pseudoephedrine from over-the-counter medicationsGeneralized dermatitis due to pseudoephedrinePigmented purpuric dermatosis due to pseudoephedrineContact sensitivity and systemic reaction to pseudoephedrine and lignocaineNonpigmenting solitary fixed drug eruption caused by pseudoephedrine hydrochlorideHistopathoiogy of dermatitis due to pseudoephedrineDrugs affecting autonomic functions or the extrapyramidal systemPseudoephedrine 15 August 1993Volume 119, Issue 4Page: 302-303KeywordsAdverse reactionsDesquamationDrugsFatigueIngestionNauseaRashesTemperatureToxic shock syndromeVomiting ePublished: 15 August 2000 Issue Published: 15 August 1993 Copyright & PermissionsCopyright © 1993 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...