Late Occurrence of Chronic Renal Failure in Familial Mediterranean Fever after 20 Years of Colchicine Treatment
Authors: Cécile Vigneau, David Petrover, Jean-Daniel Sraer
Journal: Annals of Internal Medicine (2001)

Letters18 December 2001Late Occurrence of Chronic Renal Failure in Familial Mediterranean Fever after 20 Years of Colchicine TreatmentCécile Vigneau, MD, David Petrover, MD, and Jean-Daniel Sraer, MD, PhDCécile Vigneau, MDHôpital Tenon; 75020 Paris, FranceSearch for more papers by this author, David Petrover, MDHôpital Tenon; 75020 Paris, FranceSearch for more papers by this author, and Jean-Daniel Sraer, MD, PhDHôpital Tenon; 75020 Paris, FranceSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-135-12-200112180-00030 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Since 1972, colchicine has been used to treat familial Mediterranean fever. Colchicine has good efficacy for reducing frequency of attacks and renal amyloidosis in both native and transplanted kidneys, even at the nephrotic stage (1-4). We report two cases of chronic renal failure due to amyloidosis despite very long treatment with colchicine in patients with familial Mediterranean fever.In 1982, a 46-year-old Sepharad man was admitted to the hospital because of attacks of familial Mediterranean fever and the nephrotic syndrome. Amyloidosis was proved by kidney biopsy. With colchicine treatment, proteinuria disappeared. The nephrotic syndrome reappeared in April ...References1. Goldfinger SE. Colchicine for familial Mediterranean fever. N Engl J Med. 1972;287:1302. [PMID: 4636899] CrossrefMedlineGoogle Scholar2. Simşek B, Işlek I, Simşek T, Küçüködük S, Cengiz K. Regression of nephrotic syndrome due to amyloidosis secondary to familial Mediterranean fever following colchicine treatment [Letter]. Nephrol Dial Transplant. 2000;15:281-2. [PMID: 10648685] CrossrefMedlineGoogle Scholar3. Zemer D, Livneh A, Langevitz P. Reversal of the nephrotic syndrome by colchicine in amyloidosis of familial Mediterranean fever [Letter]. Ann Intern Med. 1992;116:426. [PMID: 1736782] LinkGoogle Scholar4. Ben-Chetrit E, Levy M. Familial Mediterranean fever. Lancet. 1998;351:659-64. [PMID: 9500348] CrossrefMedlineGoogle Scholar5. Thervet E, Noel LH, Legendre C, Page B, Kreis H. Late histological recurrence of familial Mediterranean fever amyloidosis after renal transplantation [Letter]. Nephrol Dial Transplant. 1994;9:218-9. [PMID: 8190345] MedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Cécile Vigneau, MD; David Petrover, MD; Jean-Daniel Sraer, MD, PhDAffiliations: Hôpital Tenon; 75020 Paris, France PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byInfliximab Treatment of Familial Mediterranean Fever and Its Effect on Secondary AA Amyloidosis 18 December 2001Volume 135, Issue 12Page: 1096KeywordsAmyloidosisBiopsyColchicineFeversKidneysProteinuriaRenal failureRenal transplantationThyroidTreatment guidelines ePublished: 18 December 2001 Issue Published: 18 December 2001 Copyright & PermissionsCopyright © 2001 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...