Colony-Stimulating Factor and Drug-Induced Agranulocytosis
Authors: André Delannoy
Journal: Annals of Internal Medicine (1989)

Letters and Corrections1 June 1989Colony-Stimulating Factor and Drug-Induced AgranulocytosisAndré Delannoy, MD, Myriam Géhenot, MDAndré Delannoy, MDSearch for more papers by this author, Myriam Géhenot, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-110-11-942_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editor: In a recently published UCLA conference (1), Golde reviewed the therapeutic applications of colony-stimulating factors. We suggest that some patients with drug-induced agranulocytosis may also benefit from this experimental therapy.A 65-year-old woman was hospitalized because of dipyrone-induced agranulocytosis. Her leukocyte count was 800/¼ L, with 10 neutrophils, 720 lymphocytes, 10 basophils, and 60 large lymphocytes (day 0). No myeloid cells were found in the bone marrow. Human recombinant granulocyte-macrophage colony-stimulating factor (GM-CSF), 400 μg daily, was administered intravenously from day 1 to day 4. The neutrophil and immature granulocyte counts increased rapidly from 40/¼L (day 1)...References1. Golde D. In vivo studies with granulocyte-macrophage colony-stimulating factors, pp 301-2. In: Weisbart RH. Colony-stimulating factors and host defense. Ann Intern Med. 1989;110:297-303. MedlineGoogle Scholar2. RudovicJelic RS. Haematological aspects of drug-induced agranulocytosis. Scand J Haemat. 1972;9:18-27. MedlineGoogle Scholar3. . Risks of agranulocytosis and aplastic anemia: a first report of their relation to drug use with special reference to analgesics. JAMA. 1986;256:1749-57. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Hôpital de Jolimont Haine-Saint-Paul Belgium PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByMetamizole Use Among Hispanics in Miami: Report of a Survey Conducted in a Primary Care SettingDipyrone-Induced Granulocytopenia: A Case for AwarenessNonchemotherapy Drug-Induced Agranulocytosis: A Review of 118 Patients Treated with Colony-Stimulating FactorsRecombinant Human Granulocyte Colony-Stimulating Factor in Treatment of Methimazole-Induced AgranulocytosisRECOMBINANT HUMAN GRANULOCYTE COLONY-STIMULATING FACTOR IN TREATMENT OF METHIMAZOLE-INDUCED AGRANULOCYTOSISImmune mediated agranulocytosis and anemia associated with thymomaSuccessful Treatment of Carbimazole-Induced Agranulocytosis and Severe Sepsis with Granulocyte Macrophage Colony Stimulating FactorGranulozytopenien — AgranulozytoseDrug-Induced Immune NeutropeniaGranulocyte-Colony Stimulating Factor for Sulfasalazine-Induced AgranulocytosisClozapine-induced agranulocytosis and colony-stimulating cytokinesSevere phenytoin-induced bone marrow depression and agranulocytosis treated with human recombinant granulocyte-macrophage colony-stimulating factorGM-CSF in the treatment of a patient with severe methotrexate intoxicationTreatment of drug-induced agranulocytosis with recombinant granulocyte colony-stimulating factor (rh G-CSF)Recombinant granulocyte colony-stimulating factor for dapsone-induced agranulocytosis in leukocytoclastic vasculitisSouthwestern Internal Medicine Conference: Clinical Use of Hematopoietic Growth FactorsRegulation of granulocytosis in inflammatory disease and in LeukemiaHaematologic effects of granulocyte-macrophage colony stimulating factor in a patient with thiamazole-induced agranulocytosisLetter to the editor: Successful treatment of methimazole-induced agranulocytosis by granulocyte colony-stimulating factorGM-CSF therapy for drug-induced agranulocytosisDrug-Induced Blood DisordersCorrespondenceGranulozytopenien — AgranulozytoseAgranulocytosis from antiarrhythmic agentsTreatment of drug-induced agranulocytosis with recombinant GM-CSFMethimazole-Induced Agranulocytosis and Granulocyte-Colony Stimulating FactorB. Heinrich, M. Gross, MD, F.D. Goebel, MD 1 June 1989Volume 110, Issue 11Page: 942-943KeywordsBasophilsBone marrowCellsColony stimulating factorDrug therapyDrugsGranulocyte macrophage colony stimulating factorGranulocytesLymphocytesNeutrophils Issue Published: 1 June 1989 PDF DownloadLoading ...