Immune Complexes in Thrombotic Thrombocytopenic Purpura
Authors: ROBERT J. MEISTER
Journal: Annals of Internal Medicine (1979)

Letters and Corrections1 April 1979Immune Complexes in Thrombotic Thrombocytopenic PurpuraROBERT J. MEISTER, M.D., RONALD A. SACHER, M.B., B.CH., TERENCE PHILLIPS, PH.D.ROBERT J. MEISTER, M.D.Search for more papers by this author, RONALD A. SACHER, M.B., B.CH.Search for more papers by this author, TERENCE PHILLIPS, PH.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-90-4-717_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: We read with interest the recent case report of thrombotic thrombocytopenic purpura by Ansell, Beaser, and Pechet (1) in the November 1978 issue, and we concur with their recommendation to use exchange transfusion as the primary mode of therapy. One theory proposed to explain the efficacy of exchange transfusion in this syndrome is that the exchange is a means of clearing circulating immune complexes that are responsible for the manifestations of the disease. To date, it has not been possible, however, to identify immune complexes in thrombotic thrombocytopenic purpura except when the syndrome has been associated with...References1. ANSELLBEASERPECHET JRL: Thrombotic thrombocytopenic purpura fails to respond to fresh frozen plasma infusion. Ann Intern Med 89:647-648, 1978 LinkGoogle Scholar2. NEAMEHIRSH PJ: Circulating immune complexes in thrombotic thrombocytopenic purpura (letter). Blood 51:559, 1978 CrossrefMedlineGoogle Scholar3. VINCENTREVILLARD CJ: Determination of circulating immune complexes. Comparison between agglutination inhibition and C1q precipitation in polyethylene glycol-EDTA. Pathol Biol (Paris) 26:73-79, 1978 MedlineGoogle Scholar4. PHILLIPSDRAPER TC: Circulating immune complexes in schistosomiasis due to Schistosoma mansoni. Br Med J 2:476-477, 1975 CrossrefMedlineGoogle Scholar5. SOBELBOKISCHMILLER-EBERHARD AVH: C1q deviation test for the detection of immune complexes, aggregates of IgG, and bacterial products in human serum. J Exp Med 142:139-150, 1975 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Georgetown University Hospital Washington, DC 20007 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByCharacterization of platelet glycoproteins and platelet/endothelial cell antibodies in patients with thrombotic thrombocytopenic purpuraReview of thrombotic thrombocytopenic purpurain the setting of systemic lupus erythematosusProtein A-Immunoadsorption in Chemotherapy Associated Hemolytic-uremic SyndromeCase Report: Thrombotic Thrombocytopenic Purpura in a Patient with Polymyositis: Therapeutic Importance of Early Recognition and Discussion of Pathogenic MechanismsThrombotic Thrombocytopenic Purpura in Patients with the Acquired Immunodeficiency Syndrome (AIDS)-Related Complex A Report of Two CasesJagadamma M.G. Nair, MD, Rita Bellevue, MD, Maud Bertoni, MD, Harvey Dosik, MDThrombotic thrombocytopenic purpura in human immunodeficiency (HIV)-seropositive malesThrombotic Thrombocytopenic PurpuraSeltener Gehirnbefund beim „plötzlichen Kindstod“(Beitrag zum Moschcowitz-Syndrom)Thrombotisch-thrombozytopenische PurpuraCase report: Acute thrombotic thrombocytopenic purpura and cholecystitisHemolytic Uremic Syndrome and Thrombotic Thrombocytopenic PurpuraComplement in thrombotic thrombocytopenic purpuraSuccessful Treatment of Hemolytic Uremic Syndrome and Thrombotic Thrombocytopenic Purpura with Fresh Frozen Plasma and Plasma ExchangeThrombocytopenia, hemolytic anemia and transient neurologic deficitsTHROMBOTIC THROMBOCYTOPENIC PURPURA: CONFLICTING RESULTS OF IN-VITRO STUDIES 1 April 1979Volume 90, Issue 4Page: 717-717KeywordsImmune complexThrombotic thrombocytopenic purpura Issue Published: 1 April 1979 PDF DownloadLoading ...