Adenocarcinoma of the Vater's Ampulla and von Recklinghausen Disease
Authors: François Paraf, Thierry Poynard, Pierre Bedossa, Francois Gayral, Sylvie Naveau, Jean-Pierre Pignon, Guy Lemaigre, Jean-Claude Chaput
Journal: Annals of Internal Medicine (1987)

Letters and Corrections1 November 1987Adenocarcinoma of the Vater's Ampulla and von Recklinghausen DiseaseFRANÇOIS PARAF, M.D., THIERRY POYNARD, M.D., Ph.D., PIERRE BEDOSSA, M.D., FRANCOIS GAYRAL, M.D., SYLVIE NAVEAU, M.D., JEAN-PIERRE PIGNON, M.D., GUY LEMAIGRE, M.D., JEAN-CLAUDE CHAPUT, M.D.FRANÇOIS PARAF, M.D.Search for more papers by this author, THIERRY POYNARD, M.D., Ph.D.Search for more papers by this author, PIERRE BEDOSSA, M.D.Search for more papers by this author, FRANCOIS GAYRAL, M.D.Search for more papers by this author, SYLVIE NAVEAU, M.D.Search for more papers by this author, JEAN-PIERRE PIGNON, M.D.Search for more papers by this author, GUY LEMAIGRE, M.D.Search for more papers by this author, JEAN-CLAUDE CHAPUT, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-107-5-785_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Sprengers and associates (1) report the first two cases of obstructive jaundice related to primary bile duct carcinoma in patients with von Recklinghausen disease. Carcinomas of the gastrointestinal tract, bile duct, and pancreas have been reported in association with neurofibromatosis, but seem under-represented in comparison with the general population (2). We report carcinoma of the Vater's ampulla in a patient with von Recklinghausen disease.A 65-year-old man with known cutaneous neurofibromatosis was hospitalized because of painless jaundice. His total serum bilirubin level was 366 µmol/L and alkaline phosphatase level, 756 IU/L. Carcinoembryonic antigen level was not increased....References1. SPRENGERSKNOCKAERTVAN STEENBERGENPENNINCKX DDWF. Primary bile duct carcinoma and von Recklinghausen disease [Letter]. Ann Intern Med. 1987;106:772. LinkGoogle Scholar2. SORENSENMUBIRHILLNIELSEN SJA. Long-term follow-up of von Recklinghausen neurofibromatosis: survival and malignant neoplasm. N Engl J Med. 1986;314:1010-5. CrossrefMedlineGoogle Scholar3. DAYALTALLBERGNUNNEMACHERDE LELLISWOLFE YKGRH. Duodenal carcinoids in patients with and without neurofibromatosis: a comparative study. Am J Surg Pathol. 1986;10:348-57. CrossrefMedlineGoogle Scholar4. NIVABU-AVIDOREN YSM. Adenocarcinoma of pancreas and duodenum associated with cutaneous neurofibromatosis. Am J Med. 1987;82:384-5. CrossrefMedlineGoogle Scholar5. MARTIN E. A new aetiology in chronic pancreatitis: the para-ampullary duodenal cysts. Biol Gastroenterol. 1976;9:53-4. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByPolyps of the Small IntestinePatients with sporadic duodenal adenoma are a high-risk group for advanced colorectal neoplasia: results of a caseâcontrol studyGastrointestinal Neurofibromatosis: An Unusual Cause of Gastric Outlet ObstructionAmpullary Adenocarcinoma in Neurofibromatosis Type 1. Case Report and Literature ReviewPancreatic cancer and hypercalcemia associated with von Recklinghausen's disease 1 November 1987Volume 107, Issue 5Page: 785-785KeywordsAdenocarcinomaBile ductsBilirubinCarcinoembryonic antigenGastrointestinal tractNeurofibromatosis type 1PancreasPhosphatases Issue Published: 1 November 1987 PDF DownloadLoading ...