Subcutaneous Nodules Caused by Histoplasma capsulatum
Authors: Robert W. King, Sompong Kraikitpanitch, Robert D. Lindeman
Journal: Annals of Internal Medicine (1977)

Letters1 May 1977Subcutaneous Nodules Caused by Histoplasma capsulatumROBERT W. KING JR., M.D., SOMPONG KRAIKITPANITCH, M.D., ROBERT D. LINDEMAN, M.D., F.A.C.P.ROBERT W. KING JR., M.D., SOMPONG KRAIKITPANITCH, M.D., ROBERT D. LINDEMAN, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-86-5-586 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptDisseminated histoplasmosis may involve many organ systems, but involvement of subcutaneous tissue occurs infrequently (1). We recently observed two patients receiving immunosuppressive therapy after renal transplantation who developed granulomatous subcutaneous nodules caused by Histoplasma capsulatum without other evidence of disseminated disease.A 45-year-old man developed end-stage renal disease secondary to chronic glomerulonephritis and began chronic hemodialysis in October 1972. In September 1973 he received a cadaver renal allograft. After transplantation he received azathioprine, methylprednisolone, cyproheptadine, diuretics, and antihypertensives.In August 1974 he developed a painless subcutaneous nodule in his left axilla. A biopsy of the nodule showed fatty necrosis with...References1. SMITHUTZ JJ: Progressive disseminated histoplasmosis. Ann Intern Med 76:557-565, 1972 LinkGoogle Scholar2. RIFKINDMARCHIOROSCHNECK DTS: Systemic fungal infections complicating renal transplantation and immunosuppressive therapy. Am J Med 43:28-38, 1967 CrossrefMedlineGoogle Scholar3. MILLERKEDDIEJOHNSTONE HFH: Histoplasmosis. Cutaneous and mucomembranous lesions, mycologic and pathologic observations. Arch Dermatol Syph 56:715-739, 1947 CrossrefGoogle Scholar4. SAROSIVOTHDAHL GDB: Disseminated histoplasmosis: results of long-term follow-up. Ann Intern Med 75:511-516, 1971 LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByAn Unusual Subcutaneous Mass in an Otherwise Healthy Patient: A Case Report of Localized Histoplasmosis Diagnosed on Excisional BiopsyCutaneous histoplasmosis in renal transplant recipientsHistoplasmosis and subcutaneous nodules in a kidney transplant recipient: erythema nodosum versus fungal panniculitisHISTOPLASMOSISHistoplasmosis Infection Presenting as an Isolated Subcutaneous Periarticular Upper Limb Swelling in the Immunosuppressed PatientInfection in the Organ Transplant RecipientSubcutaneous Pseudallescheriasis in a renal transplant recipientInfection in the Organ Transplant RecipientHistoplasmosisInfection in the Renal and Liver Transplant PatientInfection in the Cardiac Transplant PatientDisseminated histoplasmosis in renal transplant recipients 1 May 1977Volume 86, Issue 5Page: 586-587KeywordsDiureticsGlomerulonephritisHistoplasma capsulatumHistoplasmosisImmunosuppressivesMetastasisNecrosisRenal failureRenal transplantationTransplantation Issue Published: 1 May 1977 PDF DownloadLoading ...