RECENT OBSERVATIONS REGARDING THE PATHOGENESIS AND TREATMENT OF ACQUIRED AUTOIMMUNE HEMOLYTIC ANEMIA
Authors: PAUL W. CLOUGH
Journal: Annals of Internal Medicine (1957)

Editorial1 April 1957RECENT OBSERVATIONS REGARDING THE PATHOGENESIS AND TREATMENT OF ACQUIRED AUTOIMMUNE HEMOLYTIC ANEMIAPAUL W. CLOUGH, M.D.PAUL W. CLOUGH, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-46-4-819 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAutoimmune hemolytic anemia is a designation commonly applied to a group of cases of acquired hemolytic anemia in which neither an inherited abnormality of the cells nor an extrinsic cause, such as an infection or drug intoxication, can be found. This syndrome may appear in previously normal individuals, the "idiopathic group." An identical form may be found in a few subjects with certain serious underlying diseases (the "symptomatic" group), most often in lymphatic leukemia or lymphoma, more rarely in other malignant neoplasms, disseminated lupus, periarteritis nodosa, cirrhosis.Cases of this acquired type have been recognized for 50 years, since the...1 Dameshek W: Hemolysins as the cause of clinical and experimental hemolytic anemias with particular reference as to the nature of spherocytosis and increased fragility, Am. J. M. Sc. 196: 759, 1938. CrossrefGoogle Scholar2 DameshekSchwartz WSO: Acute hemolytic anemia (acquired hemolytic icterus, acute type), Medicine 19: 231-327, 1940. CrossrefGoogle Scholar3 Vaughn JH: Immunologic features of erythrocyte sensitization. I. Acquired hemolytic disease, Blood 11: 1085-1096, 1956. CrossrefMedlineGoogle Scholar4 Dacie JV: Acquired hemolytic anemia. With special reference to the antiglobulin (Coombs') reaction, Blood 8: 813-823, 1953. CrossrefMedlineGoogle Scholar5 Gardner FH: The effect of adrenocorticotropic hormone (ACTH) in idiopathic acquired hemolytic anemia as related to the hemolytic mechanism, J. Lab. and Clin. Med. 37: 444-457, 1951. MedlineGoogle Scholar6 Moulton SE: Blood stream invasion by Newcastle disease virus associated with hemolytic anemia and encephalopathy, Am. J. Med. 14: 294-306, 1952. CrossrefGoogle Scholar7 Dameshek W: The treatment of acquired hemolytic anemia with adrenocorticotrophic hormone (ACTH), New England J. Med. 244: 117, 1951. CrossrefGoogle Scholar8 DameshekRosenthal WMC: The treatment of acquired hemolytic anemia. With a note on the relationship of periarteritis nodosa to hemolytic anemia, M. Clin. North America 35: 1423-1440, 1951. CrossrefMedlineGoogle Scholar9 Meyers MC: The use of ACTH and cortisone in idiopathic thrombocytopenic purpura and idiopathic acquired hemolytic anemia, Ann. Int. Med. 37: 352-361, 1952. LinkGoogle Scholar10 Sacks MS: Diagnosis and treatment of acquired hemolytic anemia, J. A. M. A. 150: 1556-1559, 1952. CrossrefMedlineGoogle Scholar11 Young LE: The long term picture in autoimmune hemolytic disease, Tr. A. Am. Physicians 66: 190-199, 1953. MedlineGoogle Scholar12 DameshekKomninos WZD: The present status of treatment of autoimmune hemolytic anemia with ACTH and cortisone, Blood 11: 648-664, 1956. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByNeurological Manifestations Associated with Cold Hemagglutinin Syndrome Report of Two CasesThe Selection and Care of Patients with Hemolytic Anemia for SurgeryAktuelle Probleme antikörperbedingter hämolytischer Erkrankungen 1 April 1957Volume 46, Issue 4Page: 819-826KeywordsCellsCirrhosisDrugsHemolytic anemiaIntoxicationLymphocytic leukemiaLymphomaMetastasisPathogenesis Issue Published: 1 April 1957 PDF DownloadLoading ...