Estimated Glomerular Filtration Rate
Authors: Pierre Delanaye, Etienne Cavalier, Jean-Marie Krzesinski
Journal: Annals of Internal Medicine (2007)

Letters2 January 2007Estimated Glomerular Filtration RatePierre Delanaye, MD, Etienne Cavalier, PhD, and Jean-Marie Krzesinski, MD, PhDPierre Delanaye, MDFrom University of Liége, Centre Hospitalier Universitaire de Liége, 4000 Liége Sart Tilman, Belgium.Search for more papers by this author, Etienne Cavalier, PhDFrom University of Liége, Centre Hospitalier Universitaire de Liége, 4000 Liége Sart Tilman, Belgium.Search for more papers by this author, and Jean-Marie Krzesinski, MD, PhDFrom University of Liége, Centre Hospitalier Universitaire de Liége, 4000 Liége Sart Tilman, Belgium.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-146-1-200701020-00020 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR: The recent article about estimated glomerular filtration rate (GFR) by Levey and colleagues (1) is remarkable. The authors suggest that the new equation may still have some bias and especially may have less precision in patients with GFRs greater than 60 mL/min per 1.73 m2. This is even more important if the GFR is greater than 90 mL/min per 1.73 m2. In the paper's Methods section, Levey and colleagues do not give the analytic coefficient of variation (CV) of their assays (Beckman Synchron CX3 [Global Medical Instrumentation, Inc., Ramsey, Minnesota] and Roche/Hitachi P module Creatinase Plus enzymatic ...References1. Levey AS, Coresh J, Greene T, Stevens LA, Zhang YL, Hendriksen S, et al. Using standardized serum creatinine values in the Modification of Diet in Renal Disease Study equation for estimating glomerular filtration rate. Ann Intern Med. 2006;145:247-54. [PMID: 16908915] LinkGoogle Scholar2. Costongs GM, Janson PC, Bas BM, Hermans J, van Wersch JW, Brombacher PJ. Short-term and long-term intra-individual variations and critical differences of clinical chemical laboratory parameters. J Clin Chem Clin Biochem. 1985;23:7-16. [PMID: 3981091] MedlineGoogle Scholar3. Ricós C, Alvarez V, Cava F, García-Lario JV, Hernández A, Jiménez CV, et al. Current databases on biological variation: pros, cons and progress. Scand J Clin Lab Invest. 1999;59:491-500. [PMID: 10667686] CrossrefMedlineGoogle Scholar4. Froissart M, Rossert J, Jacquot C, Paillard M, Houillier P. Predictive performance of the modification of diet in renal disease and Cockcroft-Gault equations for estimating renal function. J Am Soc Nephrol. 2005;16:763-73. [PMID: 15659562] CrossrefMedlineGoogle Scholar5. Delanaye P, Cavalier E, Krzesinski JM, Chapelle JP. Why the MDRD equation should not be used in patients with normal renal function (and normal creatinine values)? [Letter]. Clin Nephrol. 2006;66:147-8. [PMID: 16939074] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Pierre Delanaye, MD; Etienne Cavalier, PhD; Jean-Marie Krzesinski, MD, PhDAffiliations: From University of Liége, Centre Hospitalier Universitaire de Liége, 4000 Liége Sart Tilman, Belgium.Disclosures: None disclosed. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoUsing Standardized Serum Creatinine Values in the Modification of Diet in Renal Disease Study Equation for Estimating Glomerular Filtration Rate Andrew S. Levey , Josef Coresh , Tom Greene , Lesley A. Stevens , Yaping (Lucy) Zhang , Stephen Hendriksen , John W. Kusek , and Frederick Van Lente , for the Chronic Kidney Disease Epidemiology Collaboration*Estimated Glomerular Filtration Rate Andrew S. Levey , Josef Coresh , and Frederick Van Lente Correction: Estimated Glomerular Filtration Rate Metrics Cited byEstimating Baseline Kidney Function in Hospitalized Patients with Impaired Kidney FunctionThe Clinician and Estimation of Glomerular Filtration Rate by Creatinine-based Formulas 2 January 2007Volume 146, Issue 1Page: 74KeywordsBiologistsConflicts of interestCreatinineDiagnostic techniquesDietEnzyme assaysEstimated glomerular filtration rateRenal diseases ePublished: 2 January 2007 Issue Published: 2 January 2007 Copyright & PermissionsCopyright © 2007 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...