Update in Oncology
Authors: Lowell E. Schnipper
Journal: Annals of Internal Medicine (2007)

Updates4 December 2007Update in OncologyLowell E. Schnipper, MD*Lowell E. Schnipper, MD*From Beth Israel Deaconness Medical Center, Boston, Massachusetts.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-147-11-200712040-00008 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail This Update in Oncology reviews the most important articles relevant to oncology that were published in 2006. The Table summarizes changes to clinical practice that should emerge from these articles. They reflect improvement in the use of standard chemotherapy for ovarian and gastric cancers, guidance for managing patients with type II Lynch syndrome, possible new screening approaches for lung cancer, and application of targeted molecular therapies to important clinical problems.Table. Changes to Clinical Practice Emerging from Articles Important to Oncologists in 2006Lung Cancer Sandler A, Gray ...References1. Schiller JH, Harrington D, Belani CP, Langer C, Sandler A, Krook J, et al; Eastern Cooperative Oncology Group. Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer. N Engl J Med. 2002;346:92-8. [PMID: 11784875] CrossrefMedlineGoogle Scholar2. Unger M. A pause, progress, and reassessment in lung cancer screening [Editorial]. N Engl J Med. 2006;355:1822-4. [PMID: 17065645] CrossrefMedlineGoogle Scholar3. Bach PB, Jett JR, Pastorino U, Tockman MS, Swensen SJ, Begg CB. Computed tomography screening and lung cancer outcomes. JAMA. 2007;297:953-61. [PMID: 17341709] CrossrefMedlineGoogle Scholar4. Welch HG, Woloshin S, Schwartz LM. How two studies on cancer screening led to two results. New York Times. 13 March 2007; Health section. Accessed at www.nytimes.com/2007/03/13/health/13lung.html on 16 October 2007. Google Scholar5. O'Brien SG, Guilhot F, Larson RA, Gathmann I, Baccarani M, Cervantes F, et al; IRIS Investigators. Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia. N Engl J Med. 2003;348:994-1004. [PMID: 12637609] CrossrefMedlineGoogle Scholar6. Paik S, Shak S, Tang G, Kim C, Baker J, Cronin M, et al. A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer. N Engl J Med. 2004;351:2817-26. [PMID: 15591335] CrossrefMedlineGoogle Scholar7. American Cancer Society Breast Cancer Advisory Group. American Cancer Society guidelines for breast screening with MRI as an adjunct to mammography. CA Cancer J Clin. 2007;57:75-89. [PMID: 17392385] CrossrefMedlineGoogle Scholar8. Alberts DS, Liu PY, Hannigan EV, O'Toole R, Williams SD, Young JA, et al. Intraperitoneal cisplatin plus intravenous cyclophosphamide versus intravenous cisplatin plus intravenous cyclophosphamide for stage III ovarian cancer. N Engl J Med. 1996;335:1950-5. [PMID: 8960474] CrossrefMedlineGoogle Scholar9. Markman M, Bundy BN, Alberts DS, Fowler JM, Clark-Pearson DL, Carson LF, et al. Phase III trial of standard-dose intravenous cisplatin plus paclitaxel versus moderately high-dose carboplatin followed by intravenous paclitaxel and intraperitoneal cisplatin in small-volume stage III ovarian carcinoma: an intergroup study of the Gynecologic Oncology Group, Southwestern Oncology Group, and Eastern Cooperative Oncology Group. J Clin Oncol. 2001;19:1001-7. [PMID: 11181662] MedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Lowell E. Schnipper, MDAffiliations: From Beth Israel Deaconness Medical Center, Boston, Massachusetts.Disclosures: None disclosed.Corresponding Author: Lowell E. Schnipper, MD, Division of Hematology/Oncology, Beth Israel Deaconness Medical Center, 330 Brookline Avenue, Boston, MA 02215; e-mail, [email protected]harvard.edu.* Adapted for publication in Annals of Internal Medicine by Jennifer Fisher Wilson and Michael Berkwits, MD, MSCE. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 4 December 2007Volume 147, Issue 11Page: 775-782KeywordsBreast cancerCancer screeningChemotherapyChromosomesChronic myelocytic leukemiaComputed axial tomographyHereditary nonpolyposis colorectal cancerLung and intrathoracic tumorsOvarian cancerSurgery ePublished: 4 December 2007 Issue Published: 4 December 2007 Copyright & PermissionsCopyright © 2007 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...