The "Lupoid Hepatitis" Syndrome
Authors: D. ARMIN FISCHER
Journal: Annals of Internal Medicine (1962)

Case Studies1 December 1962The "Lupoid Hepatitis" SyndromeReport of a Case Followed by Serial Liver BiopsiesD. ARMIN FISCHER, M.D.D. ARMIN FISCHER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-57-6-988 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptRecurrent hepatitis with high serum gamma globulin and positive lupus erythematosus cell reactions in the blood has stimulated much comment in recent years since the first descriptions in 1955 and 1956 (1, 2). The following report describes a case of "lupoid hepatitis" followed by serial needle biopsies of the liver during 2 episodes of relapse and subsequent remissions.CASE REPORTA 45-year-old white female was first admitted to Presbyterian Hospital, Denver, Colorado, with jaundice on August 25, 1958. She had noticed symptoms on May 14, 1958, when she developed anorexia, lethargy, malaise, and upper abdominal pain. Five days later the...References1. JOSKEKING RAWE: The L.E. cell phenomenon in active chronic viral hepatitis. Lancet 2: 477, 1955. CrossrefGoogle Scholar2. MACKAYTAFTCOWLING IRLIDC: Lupoid hepatitis. Lancet 2: 1323, 1956. CrossrefGoogle Scholar3. HOLMANTOMASI HT: Lupoid hepatitis. Med. Clin. N. Amer. 44: 633, 1960. CrossrefMedlineGoogle Scholar4. MOSERMANNINGDELP MRTM: Lupoid hepatitis. J. Kansas Med. Soc. 62: 385, 1961. MedlineGoogle Scholar5. BETTLEY FR: The L.E. cell phenomenon in active chronic viral hepatitis. Lancet 2: 724, 1955. CrossrefGoogle Scholar6. HELLERZIMMERMANROSENGVAIGSINGER PHJSK: The L.E. cell phenomenon in chronic hepatic disease. New Engl. J. Med. 254: 1160, 1956. CrossrefMedlineGoogle Scholar7. HOLBOROW EJ: Serum anti-nuclear factor and auto-immunity. Proc. Roy. Soc. Med. 53: 625, 1960. CrossrefMedlineGoogle Scholar8. 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HUNTERSPARKSSELZMAN FMRDRT: Autoagglutinins in hepatic disease. Gastroenterology 39: 394, 1960. CrossrefMedlineGoogle Scholar22. COHENOHTASINGERPOPPER SGEJH: Immunocytochemical study of gamma globulin in liver in hepatitis and post necrotic cirrhosis. J. Exp. Med. 111: 285, 1960. CrossrefMedlineGoogle Scholar23. TAFTMACKAYCOWLING LIIRDC: Autoclasia; a perpetuating mechanism in hepatitis. Gastroenterology 38: 563, 1960. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Denver, ColoradoPresented at the Colorado Regional Meeting of The American College of Physicians, Colorado Springs, Colorado, January 19, 1962.Requests for reprints should be addressed to D. Armin Fischer, M.D., The National Jewish Hospital at Denver, Denver, Colorado. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByLupus hepatitis, more than just elevated liver enzymesGlomerulonephritis and renal tubular acidosis in a case of chronic active hepatitis with hyperimmunoglobulinemiaACTIVE CHRONIC HEPATITIS WITH POSITIVE L.E. CELL TEST AND LUPUS NEPHRITISNATURAL HISTORY OF ACTIVE CHRONIC HEPATITISNATURAL HISTORY OF ACTIVE CHRONIC HEPATITISChronic Active Hepatitis with Lupus NephritisE. JACK BENNER, M.D., RICHARD T. GOURLEY, M.D., ROBERT A. COOPER JR., M.D., JOHN A. BENSON JR., M.D.Concurrent “active juvenile cirrhosis” and “primary pulmonary hypertension”Chronic Active ("Lupoid") Hepatitis A Clinical, Serological, and Pathological Study of 20 PatientsMARGARET J. MACLACHLAN, M.D., GERALD P. RODNAN, M.D., F.A.C.P., WILLIAM M. COOPER, M.D., F.A.C.P., R. H. FENNELL JR., M.D.Der viscerale Lupus erythematodesKlinisch-bioptische Verlaufsbeobachtungen und Behandlungsergebnisse bei sog. „lupoider Hepatitis“Lupoid HepatitisTELFER B. REYNOLDS, M.D., F.A.C.P., HUGH A. EDMONDSON, M.D., F.A.C.P., ROBERT L. PETERS, M.D., ALLAN REDEKER, M.D.Systemic lupus erythematosusAcute Hepatitis and the Lupus Erythematosus Phenomenon 1 December 1962Volume 57, Issue 6Page: 988-994KeywordsBiopsyBlood cellsGlobulinsHepatitisHepatitis AHepatitis EHypergammaglobulinemiaLiverLupus erythematosusSteroid therapy Issue Published: 1 December 1962 PDF DownloadLoading ...