Disseminated Multiple Antibiotic-Resistant Gonococcal Infection: Needed Changes in Antimicrobial Therapy
Authors: LARRY M. BUSH
Journal: Annals of Internal Medicine (1987)

Brief Reports1 November 1987Disseminated Multiple Antibiotic-Resistant Gonococcal Infection: Needed Changes in Antimicrobial TherapyLARRY M. BUSH, M.D., JEROME A. BOSCIA, M.D.LARRY M. BUSH, M.D.Search for more papers by this author, JEROME A. BOSCIA, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-107-5-692 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptNeisseria Gonorrhoeaeusually causes a localized mucosal infection. However, in 1% to 3% of cases, the organism disseminates and produces various clinical syndromes (1). Two of the commoner manifestations of disseminated gonococcal infection are septic arthritis and tenosynovitis (2). In sexually active young persons, disseminated gonococcal infection is the most frequent cause of septic arthritis (2). In most studies on disseminated gonococcal infection, only strains ofN. gonorrhoeaethat are very sensitive to penicillin are reported to produce this syndrome (3, 4). The association between clinical virulence of the organism and dissemination may be linked to low antibiotic resistance in...References1. BARRDANIELSSON JD. Septic gonococcal dermatitis. Br Med J. 1971;1:482-5. CrossrefMedlineGoogle Scholar2. RINALDIHARRISONFAN RWP. Penicillin-resistant gonococcal arthritis: a report of four cases. Ann Intern Med. 1982;97:43-5. LinkGoogle Scholar3. WIESNERHANDSFIELDHOLMES PHK. Low antibiotic resistance of gonococci causing disseminated infection. N Engl J Med. 1973;288:1221-2. CrossrefMedlineGoogle Scholar4. THOMPSONREYNOLDSSHORT SGH. Auxotypes and antibiotic susceptibility patterns of Neisseria gonorrhoeae from disseminated and local infections. Sex Transm Dis. 1978;5:127-31. CrossrefMedlineGoogle Scholar5. . 1985 STD treatment guidelines. MMWR. 1985;34(Suppl):75S-108S. MedlineGoogle Scholar6. . Penicillinase-producing Neisseria gonorrhoeae—United States, Florida. MMWR. 1987;36:107-8. MedlineGoogle Scholar7. . Disseminated gonorrhea caused by penicillinase-producing Neisseria gonorrhoeae—Wisconsin, Pennsylvania. MMWR. 1987;36:161-2, 167. MedlineGoogle Scholar8. STRADERWISEWASILAUSKASSALZER KCBW. Disseminated gonococcal infection caused by chromosomally mediated penicillin-resistant organisms. Ann Intern Med. 1986;104:365-6. LinkGoogle Scholar9. KNAPPZENILMANBIDDLE JJJ. Frequency and distribution in the United States of strains of Neisseria gonorrhoeae with plasmid-mediated, high-level resistance to tetracycline. J Infect Dis. 1987;155:819-22. CrossrefMedlineGoogle Scholar10. RICEBIDDLEJEANLOUISDEWITTBLOUNTMORSE RJYWJS. Chromosomally mediated resistance in Neisseria gonorrhoeae in the United States: results of surveillance and reporting, 1983-1984. J Infect Dis. 1986;153:340-5. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Division of Infectious Diseases Department of Medicine The Medical College of Pennsylvania Philadelphia, Pennsylvania PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByMedical ManagementSystemic gonococcal infection.Arthritis due to a penicillinase-producingNeisseria gonorrhoeae from Saudi ArabiaAntimicrobial susceptibility testing of Neisseria gonorrhoeae and implications for epidemiology and therapyDelayed diagnosis of gonococcalarthritis of the foot caused by beta‐Iactamase‐producing Neisseria gonorrhoeaeBone and Skin InfectionsNeisseria gonorrhoeae : Une Etiologie possible de septicemie a manifestations cutaneesAcute Rheumatologic Disorders in the ElderlyGonococcal arthritis caused by auxotype P in a man with HIV infection.A Life-Threatening Gonococcal Infection 1 November 1987Volume 107, Issue 5Page: 692-693KeywordsAntibiotic resistanceAntimicrobialsArthritisGonorrheaMetastasisNeisseria gonorrhoeaePenicillin Issue Published: 1 November 1987 PDF DownloadLoading ...