tbuckley/cabot-search huggingface dataset:
Reading Joyce in the Delivery Room
Authors: Shane Neilson
Journal: JAMA (2009)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Heritability of cardiac size: an echocardiographic and electrocardiographic study of monozygotic and dizygotic twins.
Authors: T D Adams, F G Yanowitz, A G Fisher, J D Ridges, A G Nelson, A D Hagan, R R Williams, S C Hunt
Journal: Circulation (1985)

Because of the uncertainty as to the extent to which cardiac size is determined by exercise training vs genetic endowment, this study investigated familial (genetic plus common family environment) vs nonfamilial influences on cardiac size. College-age monozygotic twins (group 1, 31 sets), dizygotic twins (group 2, 10 sets), siblings of like sex (group 3, six sets), and nonrelated subjects (group 4, 15 sets) underwent echocardiographic and electrocardiographic tests, measurement of maximum oxygen uptake (VO2max), and evaluation of pulmonary and body composition; mean intrapair differences of the four groups were compared. Mean intrapair differences in cardiac size varied as much for subjects in group 1 as for those in groups 2 and 3. However, subjects in groups 1, 2, and 3 had less variation (p less than .05) than those in group 4. After the initial testing, 14 pairs of monozygotic twins, five sets of dizygotic twins, and six sets of siblings underwent 14 weeks of exercise training (both members participated) and all tests were repeated. After exercise training, subjects in group 1 still had as much intrapair variability in cardiac size as those in groups 2 and 3. The data suggest cultural familial influences are more important in determining cardiac size than nonfamilial influences or even genetic influences alone.
Letter: The UGDP scandal and cover-up
Authors: J. M. Moss
Journal: JAMA (1975)

<h3>To the Editor.—</h3> For almost five years, diabetic patients who can be safely treated with tolbutamide have been tormented by repeated headlines saying that they are being improperly and dangerously treated. Never has there been such a concerted effort to undermine the confidence of patients in their family physician. This confidence is essential for the successful treatment of any chronic disease. The original University Group Diabetes Program (UGDP) report was given to the press four weeks before it was presented to a scientific meeting where it could be adequately criticized. This report was given to the press seven months before it was published and could be adequately studied. The Food and Drug Administration endorsed the study before publication and over the objection of their own advisory committee for endocrine drugs. The witnesses who testified before Senator Nelson's committee last year were carefully selected to include only those who agreed with
Study of walk-in centres was flawed
Authors: S. George
Journal: BMJ (2001)

EDITOR—Jones in her news item reported a study that the Consumers' Association had conducted on NHS walk-in centres.1 The title of the report implies conclusive results. Jones does not, however, mention the methodological flaws of the study, and there are many.

This was a small study, designed and presented in a similar fashion to that on NHS Direct, published in August last year, which attracted criticism.2 Once again no control group was used, so we …
A tough time for paediatricians
Authors: R. Smith
Journal: BMJ (2004)

Omega 3 fatty acids can protect against heart disease Omega 3 fatty acids, which are found in fish and fish oils, can protect against coronary heart disease, but optimal intake is not firmly established.In a clinical review, Din et al (p 30) examine the evidence regarding the intake of fish oils and the risk of coronary disease.They outline the mechanisms through which fish oils might confer cardiac benefits (reduced arryhthmias,
Detoxification of 1,024 Alcoholic Patients Without Psychoactive Drugs
Authors: Charles L. Whitfield
Journal: JAMA (1978)

Most community-referred, ambulatory chronic alcoholics can be detoxified quickly and safely without the use of psychoactive drugs, according to our data. We believe such detoxification can be done most efficiently in a social setting, with the aid of a staff who will provide reassurance and reality orientation and who will monitor the patients' vital signs, general condition, and any specific problems. (<i>JAMA</i>239:1409-1410, 1978)
Empirically testable models are needed for understanding visual prediction
Authors: Giuseppe Trautteur, Edoardo Datteri, Matteo Santoro
Journal: Behavioral and Brain Sciences (2008)

Abstract Nijhawan argues convincingly that predictive mechanisms are pervasive in the central nervous system (CNS). However, scientific understanding of visual prediction requires one to formulate empirically testable neurophysiological models. The author's suggestions in this direction are to be evaluated on the basis of more realistic experimental methodologies and more plausible assumptions on the hierarchical character of the human visual cortex.
Precision over convenience
Authors: Z. Danilevicius
Journal: JAMA (1972)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Syrian doctors tell charity that "being caught with patients is like being caught with a weapon"
Authors: A. Gulland
Journal: BMJ (2012)

The charity Medecins sans Frontieres (MSF) has renewed calls for healthcare workers and medical facilities in Syria to be protected after it gained unauthorised entry to the country.

The charity, which has been seeking official authorisation to enter Syria for several months, said that wounded patients and medical workers remain targeted and threatened, and said that all parties to the conflict must fully respect the “physical integrity of wounded people, doctors, and healthcare facilities.”

Doctors from the charity managed to get into Homs …
A circadian clock in hippocampus is regulated by interaction between oligophrenin-1 and Rev-erbα
Authors: Pamela Valnegri, Malik Khelfaoui, Olivier Dorseuil, Silvia Bassani, Celine Lagneaux, Antonella Gianfelice, Roberta Benfante, Jamel Chelly, Pierre Billuart, Carlo Sala, Maria Passafaro
Journal: Nature Neuroscience (2011)
Multidimensional endotypes of asthma: topological data analysis of cross-sectional clinical, pathological, and immunological data
Authors: Timothy Hinks, Xiaoying Zhou, Karl Staples, Borislav Dimitrov, Alexander Manta, Tanya Petrossian, Pek Lum, Caroline Smith, Jon Ward, Peter Howarth, Andrew Walls, Stephan D Gadola, Ratko Djukanović
Journal: The Lancet (2015)
Carbon Monoxide Effect on Exercise-Induced Angina Pectoris
Authors: WILBERT S. ARONOW
Journal: Annals of Internal Medicine (1973)

In a double-blind study, 10 patients with angina exercised until they developed angina, before and after breathing 50 ppm carbon monoxide on two mornings for 2 hours and compressed, purified air on two mornings for 2 hours. The mean carboxyhemoglobin levels were 1.07% before and 0.77% after breathing purified air (P < 0.001) and 1.03% before and 2.68% after breathing carbon monoxide (P < 0.001). The mean exercise times until onset of angina were 226.7 seconds before and 223.0 seconds after breathing purified air (not significantly different) and 224.3 seconds before and 187.6 seconds after breathing carbon monoxide (P < 0.001). At angina there was a significant decrease in systolic blood pressure, heart rate, and product of systolic blood pressure times heart rate after breathing carbon monoxide (P < 0.001) but not after breathing purified air, compared with control levels. Breathing 50 ppm carbon monoxide for 2 hours induced angina sooner and after less cardiac work.
Antioxidant Supplements and Cardiovascular Disease in Men
Authors: Francesco Violi
Journal: JAMA (2009)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
US health professionals helped in the torture of detainees, report says
Authors: M. McCarthy
Journal: BMJ (2013)

US physicians, psychologists, and other health professionals aided in the harsh interrogation and torture of prisoners held in Afghanistan, Iraq, Guantanamo Bay, and other overseas detention centers operated by the US military and the Central Intelligence Agency as part of the United States’ “war on terror,” says a new report.1

The participation of US military and intelligence agency medical personnel in these practices was “in clear conflict with established international and national professional principles and laws,” the report found.

The report, Ethics Abandoned: Medical Professionalism and Detainee Abuse in the “War on Terror,” was prepared by a task force of 20 physicians, lawyers, ethicist and human rights experts funded by the Institute on Medicine as a Profession, a health policy think tank based at Columbia University in New York City, and the Open Society Foundation, a grant-making organization founded by billionaire philanthropists George Soros. The report was based on unclassified, publicly available information.

After the 9/11 terrorists attacks in September 2001, the US government ruled that suspected terrorists captured in Afghanistan and …
CARDIOPROTECTION BY STIMULATION OF MITOCHONDRIAL BENZODIAZEPINE RECEPTORS DURING REPERFUSION, IN A PORCINE ACUTE ISCHEMIA-REPERFUSION MODEL
Authors: John Terrovitis, Lampros Katsaros, Michalis Tsamatsoulis, Stefania Sventzouri, Vassilios Sousonis, Michalis Bonios, Christos Kapelios, Styliani Vakrou, Argyrios Ntalianis, Apostolos Papalois, Brian O&apos;Rourke, John Nanas
Journal: Journal of the American College of Cardiology (2012)
You-July ’70
Authors: Ann R. Punnoose
Journal: JAMA (2012)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
990-52 Long-term Prognostic Significance of Treadmill Ischemia in “Low-risk” Patients with Coronary Artery Disease
Authors: David Mulcahy, Asif Rehman, Syed S. Husain, Neil P. Andrews, Gloria Zalos, William H. Schenke, Arshed A. Ouyyumi
Journal: Journal of the American College of Cardiology (1995)
Mentally ill people need more help to stay in work, says chief medical officer
Authors: Z. Kmietowicz
Journal: BMJ (2014)

People with mental illness should have more help to stay in work, including prompt NHS treatment and support from employers, such as flexible working hours, England’s chief medical officer has said.

In her annual report Sally Davies said that the number of working days lost to stress, depression, and anxiety in the United Kingdom had risen by 24% since 2009.1 Altogether 70 million working days were lost to mental illness in the UK in 2013, with a cost to the economy of between £70bn (€87bn; $113bn) and £100bn.

Davies called for the National Institute for Health and Care Excellence to look at whether accelerating access to treatment for people who work improves their chances of avoiding sick leave.

People …
Occupational asthma and rhinitis caused by ash (Fraxinus excelsior) wood dust
Authors: M. Fernández‐Rivas, C. Pérez‐Carral, C. J. Senent
Journal: Allergy (1997)

An 18‐year‐old man who worked in a furniture factory reported rhinitis and asthma when he was exposed to ash wood dust. Monitoring of the patient's peak expiratory flow rate (PEFR) when off work and at work showed increased variations of PEFR at work. Basal PC 20 methacholine was 1.41 mg/ml. A bronchial provocation test (BPT) with a 1: 1000 w/v ash wood dust extract induced a dual asthmatic response with a 7.5‐fold increase of nonspecific bronchial responsiveness. Intradermal testing with ash wood extract elicited a positive immediate response. IgE antibodies against ash wood were found in the patient's serum with a RAST value of 0.57 PRU/ml. Similar skin tests, BPT, and RAST with ash wood dust performed in control patients were all negative. All the studies performed suggest that our patient had occupational rhinitis and asthma caused by exposure to ash wood dust in which a type I immunologic mechanism was implicated.
The Learning Group
Authors: VAMIK D. VOLKAN, DAVID R. HAWKINS
Journal: American Journal of Psychiatry (1972)

The authors describe a group approach to training first-year residents in which direct observation of patient-therapist interaction, seminars with guest experts, and preceptorship methods are combined. In these groups of six to eight residents, meeting with a tutor for 225 hours a year, anxiety is mobilized and different constellations of group dynamics develop. First-year residents need to develop therapeutic ego functions. Thus an analogy is made between psychoanalytic therapy aimed at ego-building and the learning group aimed at developing the residents' therapeutic tools on both the emotional and intellectual levels.
Immunohistochemical Expression of Endothelin-1 and Endothelin-A and Endothelin-B Receptors in High-Grade Prostatic Intraepithelial Neoplasia and Prostate Cancer
Authors: Rodolfo Montironi, Roberta Mazzucchelli, Francesca Barbisan, Daniela Stramazzotti, Alfredo Santinelli, Antonio Lòpez Beltran, Liang Cheng, Francesco Montorsi, Marina Scarpelli
Journal: European Urology (2007)
Diagnostic Use of Adrenal Inhibition in Cushing's Syndrome
Authors: C. L. Cope
Journal: BMJ (1956)

Experimental ResultsThe results support the belief that the adrenal inhibition test will prove of value in distinguishing Cushing's syndrome due to adrenal hyperplasia from cases of the syndrome due to carcinoma.Our thanks are due to Miss Elizabeth Black and to Miss Olwen Jenkins for performing most of the analyses; to the Medical Research Council for a grant for the former; and to Dr. Russell
Panitumumab–FOLFOX4 Treatment and <i>RAS</i> Mutations in Colorectal Cancer
Authors: Jean-Yves Douillard, Kelly S Oliner, Salvatore Siena, Josep Tabernero, Ronald Burkes, Mario Barugel, Yves Humblet, Gyorgy Bodoky, David Cunningham, Jacek Jassem, Fernando Rivera, Ilona Kocákova, Paul Ruff, Maria Błasińska-Morawiec, Martin Šmakal, Jean Luc Canon, Mark Rother, Richard Williams, Alan Rong, Jeffrey Wiezorek, Roger Sidhu, Scott D Patterson
Journal: New England Journal of Medicine (2013)

Patients with metastatic colorectal cancer that harbors KRAS mutations in exon 2 do not benefit from anti–epidermal growth factor receptor (EGFR) therapy. Other activating RAS mutations may also be negative predictive biomarkers for anti-EGFR therapy.
Visual Hallucinations: More Diagnoses
Authors: Stephen F. Signer
Journal: JAMA (1987)

<h3>To the Editor.—</h3> While Dr Newmark's answer<sup>1</sup>offered a good discussion, I would like to add some comments. Peduncular hallucinations are not synonymous with "release" phenomena. The latter occur with any focal lesion along the visual pathways, and as such have little localizing value, although they are most often placed in the temporal, parietal, and occipital lobes; the release hallucinations are formed, variable in content, and modified by opening or closing the eyes and are seen within the visual field defect.<sup>2-4</sup>Peduncular hallucinations are vivid, animated, short-lived, and often recognized as unreal; most of the patients reported have had signs of brain-stem dysfunction pointing to lesions in this region. As noted, a sleep abnormality is prominent and the hallucinations often occur at a specific time, usually in late daytime or evening. One patient was treated successfully when 5-hydroxytryptophan restored normal sleep.<sup>4,5</sup> Ictal visual hallucinations are brief, stereotyped,
Predictive Value of Circulating Oxidized LDL for Cardiac Events in Type 2 Diabetic Patients With Coronary Artery Disease
Authors: Kazunori Shimada, Hiroshi Mokuno, Eriko Matsunaga, Tetsuro Miyazaki, Katsuhiko Sumiyoshi, Atsumi Kume, Katsumi Miyauchi, Hiroyuki Daida
Journal: Diabetes Care (2004)

Oxidized LDL (oxLDL) has been shown to play an important role in the initiation and development of atherosclerosis (1). Individuals with type 2 diabetes exhibit enhanced LDL oxidizability and accelerated atherosclerosis (2,3). Past studies demonstrated the association between LDL oxidation and atherosclerosis by “indirect” methods, such as lag times and propagation rates for LDL oxidation, and antibodies against oxLDL. Recently, some groups have developed “direct” methods for measuring circulating oxLDL (4–6). Indeed, several lines of evidence have demonstrated that the level of circulating oxLDL is significantly higher in patients with type 2 diabetes, is a marker for identifying patients …
Traveller's diarrhoea.
Authors: C. M. Fletcher
Journal: BMJ (1968)

OU^RMthis way one rapidly adjusts to headlight glare and drives without danger.The streets of Britain are much better lit in general than the streets of my own country, but I feel much safer driving at night here.It is not the annoying glare from oncoming lights on a wet night that is the problem, it is the multitude of sudden poorly lit sections that turn up unexpectedly in any city.This is a real danger if one drives with sidelights on instead of headlights at low beam.Interestingly enough, I found that the further north one went in Britain the worse lit were the roads and the less likely were the drivers to use their headlights.Your drivers used them for signalling, for overtaking, as a token of thanks, in fact for everything but the reason they were put there-in order to see when driving at night.-I am, etc.,
Ca-mediated stimulation of Cl secretion by reactive oxygen metabolites in human colonic T84 cells.
Authors: H Tamai, T S Gaginella, J F Kachur, M W Musch, E B Chang
Journal: Journal of Clinical Investigation (1992)

Monochloramine (NH2Cl), a granulocyte-derived reactive oxygen metabolite (ROM), increases short-circuit current (Isc) in cultured T84 monolayers in a concentration-dependent manner up to nonlethal concentrations of 75 microM. Isc increases slowly after NH2Cl, reaching a peak value of 18 +/- 2 microA/cm2 20 min after addition. The Isc changes are persistent (lasting over 20-30 min), depend on medium Cl, and are inhibitable with bumetanide. 36Cl flux studies demonstrated that NH2Cl increases serosa-to-mucosa flux of Cl without changing mucosa-to-serosa flux, consistent with stimulation of electrogenic Cl secretion. Isc responses to NH2Cl, but not PGE2, are dependent on medium calcium. As demonstrated in fura-2-loaded T84 cells, NH2Cl increases free cytosolic calcium by influx of extracellular Ca2+ and by release of Ca2+ from endogenous stores. However, NH2Cl had no effect on phosphatidylinositol metabolism or cyclic nucleotide levels. We conclude that ROM directly stimulate electrolyte secretion, an effect in part mediated by increases in cytosolic Ca2+, possibly through increasing Ca2+ permeability of cellular membranes.