STUDIES IN ATHEROSCLEROSIS. III. AN EPIDEMIOLOGIC STUDY OF ATHEROSCLEROSIS IN TRAPPIST AND BENEDICTINE MONKS: A PRELIMINARY REPORT
Authors: J. Gordon Barrow, Carroll B. Quinlan, Gerald R. Cooper, Virginia S. Whitner, Mary H. R. Goodloe
Journal: Annals of Internal Medicine (1960)

Article1 February 1960STUDIES IN ATHEROSCLEROSIS. III. AN EPIDEMIOLOGIC STUDY OF ATHEROSCLEROSIS IN TRAPPIST AND BENEDICTINE MONKS: A PRELIMINARY REPORTJ. GORDON BARROW, M.D., F.A.C.P., CARROLL B. QUINLAN, M.D., GERALD R. COOPER, M.D., VIRGINIA S. WHITNER, M.S., MARY H. R. GOODLOE, B.S.J. GORDON BARROW, M.D., F.A.C.P.Search for more papers by this author, CARROLL B. QUINLAN, M.D.Search for more papers by this author, GERALD R. COOPER, M.D.Search for more papers by this author, VIRGINIA S. WHITNER, M.S.Search for more papers by this author, MARY H. R. GOODLOE, B.S.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-52-2-368 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptPrior to World War II, atherosclerosis was regarded primarily as an aging process, rather than as a disease entity. Although chemical analyses of atheromata by Windaus in 19101 revealed their high lipid and cholesterol content, and Anitschkow in 19132 demonstrated that atheromatosis could be induced in laboratory animals by feeding them a high cholesterol diet, comparatively little research was directed toward determining the etiology of atherosclerosis.During the last decade, however, investigators have become increasingly convinced that atherosclerosis is an actual disease process.3, 4, 7It is now being studied from many points of view, but the approach which will...Bibliography1. Windaus A: Uber den Gehalt normaler und atheromatoser Aorten an Cholesterin und Cholesterinestern, Ztschr. f. physiol. Chem. 67: 174, 1910. CrossrefGoogle Scholar2. Anitschkow N: Experimental arteriosclerosis in animals, in Arteriosclerosis, edited by E. V. Cowdry, 1933, The Macmillan Co., New York. Google Scholar3. DawberMeadorsMoore TRGFFE: Epidemiological approaches to heart disease: The Framingham Study, Am. J. Pub. Health 41: 279, 1951. CrossrefGoogle Scholar4. Stamler J: Current epidemiological, clinical and laboratory research findings on the etiology of atherosclerosis, Nebraska M. J. 41: 75, 1956. MedlineGoogle Scholar5. MillerStareWhiteGordon DFJPDJE: The community problem in coronary heart disease: a challenge for epidemiologic research, Am. J. M. Sc. 232: 329, 1956. MedlineGoogle Scholar6. White PD: The cardiologist enlists the epidemiologist, Am. J. Pub. Health 47 (part II): 1, 1957. Google Scholar7. Hilleboe HE: Some epidemiological aspects of coronary artery disease, paper read at the Conference on Atherosclerosis and Coronary Artery Disease, sponsored by New York Heart Association, Waldorf Astoria Hotel, New York City, January 15, 1957. Google Scholar8. Page IH: Atherosclerosis: an introduction, Circulation 10: 1, 1954. CrossrefMedlineGoogle Scholar9. Keys A: Diet and the incidence of heart disease, Bull. Univ. of Minnesota Hospitals and Minnesota Med. Foundation 24: 376, 1953. Google Scholar10. MillerTrulsonMcCannWhiteStare DCMFMBPDFJ: Diet, blood lipids and health of Italian men in Boston, Ann. Int. Med. 49: 1178, 1958. LinkGoogle Scholar11. BrockBronte-Stewart JFB: Arteriosclerosis in African populations, Symposium of the Minnesota Heart Association, Minneapolis, 1955, p. 102. Google Scholar12. Malmros H: The relation of nutrition to health. A statistical study of the effect of wartime on arterosclerosis, cardiosclerosis, tuberculosis and diabetes, Acta med. Scandinav. Suppl. 246: 137, 1950. Google Scholar13. MorrisHeadyRaffleRobertsParks JNJAPACGJW: Coronary heart disease and physical activity of work, Lancet 2: 1053, 1953. CrossrefGoogle Scholar14. BiörckOverbeckGronvall GWC: Coronarkrankheit und Herzinfarkt in Malmo, Cardiologia 25: 232, 1954. CrossrefMedlineGoogle Scholar15. FriedmanRosenman MRH: Association of specific overt behavior pattern with blood and cardiovascular findings, J. A. M. A. 169: 1286, 1959. CrossrefMedlineGoogle Scholar16. RussekZohman HIBL: Relative significance of heredity, diet and occupational stress in coronary heart disease of young adults, Am. J. M. Sc. 235: 266, 1958. CrossrefMedlineGoogle Scholar17. Wolf S: Panel: Emotional factors in atherosclerosis, Annual Meeting, American Heart Association, San Francisco, October 25, 1958. Google Scholar18. DawberMooreMann TRFEGV: Coronary heart disease in the Framingham Study, Am. J. Pub. Health 47 (part II): 4, 1957. CrossrefGoogle Scholar19. Pickering GW: High blood pressure, 1955, J. H. Churchill, London. Google Scholar20. AllenBarkerHines EVNWEA: Peripheral vascular disease, 2nd Ed., 1955, W. B. Saunders Company, Philadelphia, p. 221. Google Scholar21. AdlersbergParetsBoas DADEP: Genetics of atherosclerosis: studies of families with xanthoma and unselected patients with coronary artery disease under the age of 50 years, J. A. M. A. 141: 246, 1949. CrossrefMedlineGoogle Scholar22. Mirone L: Nutrient intake and blood findings of men on a diet devoid of meat, Am. J. Clin. Nutrition 2: 246, 1954. CrossrefMedlineGoogle Scholar23. GoodloeQuinlanBarrow MHCBJG: Studies in atherosclerosis. I. A diet record technique, Pub. Health Rep. 74: 298, 1959. CrossrefMedlineGoogle Scholar24. WhitnerCooperBarrowQuinlan VSGJGCB: Studies in atherosclerosis. II. Colorimetric methods for determining serum lipids: total and free cholesterol, phospholipids and total esterified fatty acids, to be published. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Atlanta, Georgia*Received for publication May 16, 1959.Presented at the Fortieth Annual Session of The American College of Physicians, Chicago, Illinois, April 23, 1959.From the Heart Disease Control Program, Georgia Department of Public Health, Atlanta, Georgia.†This study was supported by grant H3262 from the National Heart Institute.Requests for reprints should be addressed to J. Gordon Barrow, M.D., Director, Heart Disease Control Program, Georgia Department of Public Health, 12 Capitol Square, S. W., Atlanta 3, Georgia. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byUNNATURAL DEATHS AMONG NUNS AND MONKS: IS THERE A BIOLOGICAL FORCE BEHIND MALE EXTERNAL CAUSE MORTALITY?Causes of Male Excess Mortality: Insights from Cloistered Populations‘Does Religion Cause Health?’: Differing Interpretations and Diverse MeaningsThe Role of Nutrition in Atherogenesis and Acute Myocardial InfarctionPlant Fibers and Human HealthAltered bile acid metabolism in vegetariansDietary fibre.Ischemic heart disease and dietary fiberStudies Reporting “Low Rates” of Ischemic Heart Disease: A Critical ReviewDietary Intake of Non-Hospitalized Persons with Multiple Sclerosis1The status of risk factors and coronary heart diseaseBehavior patterns and personality characteristics related to prevalence rates of coronary heart disease in American monksReliability and validity of personality and behavioral measures in a study of coronary heart diseaseEffect of Controlled Running on Serum Cholesterol of Young Adult Males of Varying Morphological ConstitutionsDie BBC-StudieInfluence of several physical activities on serum cholesterol concentrations in young menThe epidemiology of coronary heart diseaseNon-Flesh DietariesComputers in Epidemiologic Dietary StudiesFettverzehr-Plasmacholesterin-KoronarkrankheitNon-Flesh Dietaries . II. Scientific LiteratureStudies in AtherosclerosisAn Evaluation of Clinical and Laboratory Findings in Male Subjects on Long-Term, Low-Fat, Low-Protein DietsThe Influence of Nutrition and Ways of Life on Blood Cholesterol and the Prevalence of Hypertension and Coronary Heart Disease Among Trappist and Benedictine MonksGeographic Studies of ArteriosclerosisA Study of Diet, Blood Lipids and Vascular Disease in Trappist Monks 1 February 1960Volume 52, Issue 2Page: 368-377KeywordsAtherosclerosisAttentionEpidemiologyHeartHypercholesterolemiaIngestionLipidsLongitudinal studiesPrevention, policy, and public healthResearch laboratories ePublished: 1 December 2008 Issue Published: 1 February 1960 PDF downloadLoading ...