tbuckley/cabot-search huggingface dataset:
The American Health Scandal
Authors: Thomas P. Kugelman
Journal: JAMA (1966)

This "exposé" of the deplorable state of medical care in the United States is a tedious and naïve effort by a free-lance journalist to create a potboiler with information long familiar to the educated reader. Mr. Tunley's stated purpose is to provide the public with an objective assessment of prevailing conditions, but his manner of presentation—through interviews, anecdotes, selected "statistics," and eyewitness accounts—produces a highly selected and distorted picture. Poor nursing homes and mental hospitals, high infant mortality, shortages of specialized medical facilities and physicians, uneven quality of hospitals, insufficient insurance protection, high costs, and inefficiency are his main revelations. Principal blame for these deficiencies is laid to the monolithic AMA, the "world's most hated union," which strives only to protect fee-for-service medicine and has successfully blocked progressive legislation by intimidating the federal government as well as the individual physician. The second part of the book is far more interesting
Time to turn the tide: WHO's engagement with non-state actors and the politics of stakeholder governance and conflicts of interest
Authors: J. Richter
Journal: BMJ (2014)

I am deeply concerned that WHO’s so called reform will sideline those who work in the spirit of “health for all” and expand the influence of business corporations and venture philanthropies over global public health matters, as well as reinforce the trend towards fragmented, plutocratic, global governance.

Three years ago, international non-governmental organisations highlighted the problematic link between the WHO director general’s suggestion to re-fill WHO’s coffers with funds from business …
Heart Rate Variability During Specific Sleep Stages
Authors: Emilio Vanoli, Philip B. Adamson, None Ba-Lin, Gian D. Pinna, Ralph Lazzara, William C. Orr
Journal: Circulation (1995)

Heart rate variability (HRV) is typically higher during nighttime. This evidence supports the concept that overall, sleep is a condition during which vagal activity is dominant. Myocardial infarction (MI) results in a loss in the overall nocturnal HRV increase. However, the characteristics of HRV during specific sleep stages in normal subjects and, more importantly, after MI, are unknown. This study describes HRV during sleep stages in normal subjects and in patients with a recent MI.HRV was measured from 5 minutes of continuous ECG recording in 8 subjects with no clinical evidence of coronary artery disease (age, 47 +/- 4 years) and in 8 patients with a recent MI (age, 51 +/- 2 years; NS versus control subjects) in the awake state, non-rapid eye movement (REM), and REM sleep. In normal subjects, the low- to high-frequency ratio (LF/HF) derived from power spectral analysis of HRV decreased significantly from the awake state to non-REM sleep (from 4 +/- 1.4 to 1.22 +/- 0.33, P < .01). During REM sleep, the LF/HF increased to 3 +/- 0.74 (P < .01 versus non-REM, NS versus awake). In post-MI patients, the LF/HF showed an opposite trend toward an increase from 2.4 +/- 0.7 to 5.11 +/- 1.4 (NS, P < .01 versus the control subjects). REM sleep produced a further increase in the LF/HF up to 8.9 +/- 1.6 (P < .01 versus awake and versus REM in control subjects).Myocardial infarction causes a loss in the capability of the vagus to physiologically activate during sleep. This results in a condition of relative sympathetic dominance even in a situation such as sleep, normally described as a condition of vagal dominance and, consequently, low risk for lethal events. The evidence that the sleep-related vagal activation is lost after MI may provide new insights to understanding the nocturnal occurrence of sudden death.
Evaluation of urinary porphyrin excretion in neonates born to mothers exposed to airborne hexachlorobenzene.
Authors: Dolores Ozalla, Carmen Herrero, Núria Ribas-Fitó, Jordi To-Figueras, Agustí Toll, Maria Sala, Joan Grimalt, Xavier Basagaña, Màrius Lecha, Jordi Sunyer
Journal: Environmental Health Perspectives (2002)

The existence of a link between hexachlorobenzene (HCB) and porphyria cutanea tarda has been known for a long time. However, the epidemiologic data on effects on health caused by prenatal exposure have not provided convincing evidence that HCB alters porphyrin metabolism. Our objectives were to analyze urinary porphyrin excretion and HCB in maternal serum and fetal cord blood in neonates born in a village (Flix) near a chlorinated solvent factory, to detect possible adverse effects in urinary porphyrin excretion caused by prenatal exposure, and to assess their relationship with HCB blood levels. We conducted a cross-sectional study in the Porphyria Unit at a tertiary care facility in Barcelona, Spain, and the Pediatric Unit of the Móra d'Ebre Hospital, the reference hospital of the study area. We included in the study all neonates (n = 68) born in Móra d'Ebre Hospital 1997-1999 and their mothers. We obtained 68 urine specimens of singleton neonates on the third day after birth to test for urinary porphyrin excretion. We obtained 52 fetal cord blood and 56 maternal serum samples for HCB analysis. Total urinary porphyrins were quantified using spectrofluorometry. Porphyrin profile was determined by HPLC. Serum HCB was analyzed by gas chromatography coupled with electron capture detection. In total population, median HCB levels were 1.08 ng/mL in cord blood and 3.31 ng/mL in maternal serum. Total urinary porphyrin concentration was 37.87 micromol/mol creatinine. Coproporphyrin I and coproporphyrin III were the major porphyrins excreted. We found no positive relationship between urinary porphyrin excretion and HCB levels. However, we observed an association between maternal smoking and coproporphyrin excretion. Although high environmental levels of HCB are reported in the town of Flix, we found no alteration in urinary porphyrin excretion.
Field Guide to Urgent and Ambulatory Care Procedures
Authors: Jerrold B. Leikin
Journal: Annals of Internal Medicine (2002)

Medical Writings: Book Notes19 March 2002Field Guide to Urgent and Ambulatory Care ProceduresJerrold B. Leikin, MDJerrold B. Leikin, MDEvanston Northwestern Healthcare OMEGA, Glenbrook Hospital, Glenview, Illinois.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-136-6-200203190-00023 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail James DM. 351 pages. Philadelphia: Lippincott Williams & Wilkins; 2001. $29.95. ISBN 0781728231. Order phone 800-638-0672.Field of medicine: Ambulatory general medical care.Format: Softcover book (pocket-size).Audience: Primary care (general internal medicine, family medicine, and pediatrics) and sports medicine physicians working in an outpatient, ambulatory, or urgent care setting.Purpose: To provide a straightforward, rapid, and simple guide to common procedures used in a general outpatient setting.Content: The handbook is divided into 70 chapters through 11 organ systems and a section on advanced procedures. Thirty of these chapters deal with traumatic events; the largest section focuses on musculoskeletal ... Author, Article, and Disclosure InformationAffiliations: Evanston Northwestern Healthcare OMEGA, Glenbrook Hospital, Glenview, Illinois. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 19 March 2002Volume 136, Issue 6Page: 492KeywordsEmergency medicineHealth careInfantsMuscular dystrophiesMyofascial painOutpatientsPediatricsShouldersSoftware toolsSports and exercise medicine ePublished: 19 March 2002 Issue Published: 19 March 2002 Copyright & PermissionsCopyright © 2002 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Predicting the outcome of stroke: acute stage after cerebral infarction.
Authors: J M Oxbury, R C Greenhall, K M Grainger
Journal: BMJ (1975)

On admission to hospital during the acute phase of a stroke presumed due to ischaemic infarction in one cerebral hemisphere 93 patients were examined to determine the factors associated with a poor prognosis for immediate survival. The patients particularly at risk were those who were overtly unconscious and those with any combination of impaired consciousness, dense hemiplegia, and failure of conjugate ocular gaze towards the side of the limb weakness. Necropsy evidence suggested that these signs usually indicate infarction of the whole of one middle cerebral artery territory which is often secondary to internal carotid artery occlusion and commonly produces fatal cerebral oedema.
Galen and the Rhetoric of Healing
Authors: Dorothy Porter
Journal: JAMA (2009)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Consulting the public about the NHS
Authors: W. Anderson
Journal: BMJ (2000)

Patients and members of the public in England have just been consulted by the government on how they would spend the extra funding promised to the NHS over the next five years. The consultation is meant to inform the government, which in July is publishing its plan for the NHS, defining how the increased funding will be spent (Department of Health, press release, 23 March 2000). Twelve million leaflets with prepaid response forms have been distributed through supermarkets, pharmacies, opticians, hospitals, and general practices, asking, “What are the top three things you think would make the NHS better for you and your family?” “Census day” was 31 May, when service providers were asked to actively encourage their users to fill in the leaflet. The public consultation process also includes a website, two public forums, patient representation on the six action teams for modernisation, and meetings between patients' organisations …
Tetraethylammonium induced coronary spasm in isolated perfused rabbit heart: a hypothesis for the mechanism of coronary spasm
Authors: M. IWAKI, S. MIZOBUCHI, Y. NAKAYA, K. KAWANO, T. NIKI, H. MORI
Journal: Cardiovascular Research (1987)

Journal Article Tetraethylammonium induced coronary spasm in isolated perfused rabbit heart: a hypothesis for the mechanism of coronary spasm Get access MASATERU IWAKI, MASATERU IWAKI From the Second Department of Internal Medicine, School of Medicine, Tokushima University, Tokushima, Japan Address for correspondence and reprints: Dr Yutaka Nakaya, Second Department of Internal Medicine, School of Medicine, Tokushima University, 2-50 Kuramoto-cho, Tokushima City, Tokushima, Japan 770. Search for other works by this author on: Oxford Academic PubMed Google Scholar SHIGEKI MIZOBUCHI, SHIGEKI MIZOBUCHI From the Second Department of Internal Medicine, School of Medicine, Tokushima University, Tokushima, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar YUTAKA NAKAYA, YUTAKA NAKAYA From the Second Department of Internal Medicine, School of Medicine, Tokushima University, Tokushima, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar KAZUHIRO KAWANO, KAZUHIRO KAWANO From the Second Department of Internal Medicine, School of Medicine, Tokushima University, Tokushima, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar TOSHIHARU NIKI, TOSHIHARU NIKI From the Second Department of Internal Medicine, School of Medicine, Tokushima University, Tokushima, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar HIROYOSHI MORI HIROYOSHI MORI From the Second Department of Internal Medicine, School of Medicine, Tokushima University, Tokushima, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar Cardiovascular Research, Volume 21, Issue 2, February 1987, Pages 130–139, https://doi.org/10.1093/cvr/21.2.130 Published: 01 February 1987 Article history Received: 15 January 1986 Accepted: 08 July 1986 Published: 01 February 1987
Prophylactic Use of a Probiotic in the Prevention of Colic
Authors: Sarvin Sanaie, Ata Mahmoodpoor, Samad E. J. Golzari
Journal: JAMA Pediatrics (2014)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Pediatrics HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Pediatrics journal
Global public health and the information superhighway
Authors: R E LaPorte, S Akazawa, P Hellmonds, E Boosrom, C Gamboa, T Gooch, F Hussain, I Libman, E Marler, K Roko, F Sauer, N Tajima
Journal: BMJ (1994)

Applications of networking to health care have focused on the potential of networking to transmit data and to reduce the cost of health care. In the early 198Os networks began forming among academic institutions; one of them was Bitnet. During the 1980s Internet evolved, which joined diverse networks, including those of governments and industry. The first step is to connect public health organizations such as ministries of health, the World Health Organization, the Pan-American Health Organization, and the United Nations. Computer-based telecommunication will vastly increase effective transmission of information. Networking public health workers in local health departments, academia, governments, industry, and private agencies, will bring great benefits. One is global disease telemonitoring: with new epidemiological techniques such as capture-recapture, accurate estimates of incidences of important communicable and non-communicable diseases can now be obtained. Currently all countries in the Americas except Haiti are connected through Internet. No systematic integration of telecommunication and public health systems across countries has occurred yet. On-line vital statistics could be usable almost instantaneously to facilitate monitoring and forecasting of population growth and the health needs of mothers and children. Linking global disease telemonitoring (morbidity data for non-communicable diseases) with environmental data systems would considerably improve understanding of the environmental determinants of disease. Internet is already linked to the National Library of Medicine through Bitnis. Computer based distance education is rapidly improving through E-mail searches. Reading materials, video, pictures, and sound could be transmitted across huge distances for low costs. Hundreds of schools are already networked together. On-line electronic journals and books have the potential for instantaneous dissemination of free information through gopher servers. Global public health needs to plan for a public health communication system that can reach all the public health workers in the world.
Pharmacists react angrily to government plans requiring them to check prescription exemptions
Authors: I. Torjesen
Journal: BMJ (2015)

Pharmacists have warned that government plans requiring them to check the benefits status of patients who collect free medicines without their exemption certificate could “distort” their relationship with patients.

Around 90% of prescription items in England are dispensed free of charge, but pharmacists largely rely on people’s honesty when dispensing medicines for free. When collecting prescription items from pharmacies in England patients are asked to present their exemption certificate and sign the back of the prescription form to say why they are exempt of any charge. …
Abstract 4932: Genistein Can Induce Demethylation Of Wnt Negative Regulatory Genes In Prostate Cancer Cells
Authors: Cornel J. Phillip, Carlos S. Moreno
Journal: Cancer Research (2010)

Abstract Among American men, prostate cancer is a prevalent malignancy that accounts for an estimated 192,280 new cases and 27,360 deaths in 2009. Previous work has determined that the adenomatous polyposis coli (APC) gene that negatively regulates the Wnt pathway is hypermethylated in a high proportion of prostate cancers. We hypothesized that methylation of additional Wnt negative regulatory genes may also play a role in prostate cancer progression such as SRY box 7 (SOX7), Wnt inhibitory factor 1 (WIF1), secreted frizzled-related protein 1 (SFRP1) and dickkopf-related protein 3 (DKK3). To test this hypothesis, the basal level methylation status was tested in several prostate cancer patient tumor and adjacent normal samples by methylation specific PCR. When the methylation status of some of these genes was explored, there was variation in the methylation of some of these genes, particularly DKK3 among different patients. This preliminary finding may suggest that the methylation status of some of these genes may play a role in the progression of prostate cancer. In this study, we propose that demethylation of these Wnt negative regulatory genes may allow for a decrease activity of the Wnt signaling pathway. Genistein is a soy isoflavone that has many potentially therapeutic activities, including demethylation of DNA. We hypothesized that treatment of prostate cancer cells could lead to demethylation and re-expression of these genes. To test our hypothesis, prostate cancer cell lines LNCAP and DU145 were treated with for 6 days with concentrations of 5, 10, and 20 µM genistein. We observed a dose-dependent reduction in methylation of SOX7, DKK3, WIF1, and SFRP1. Taken together, these data indicate that genistein may have therapeutic value for patients with prostate cancer. As a therapeutic agent, genistein treatment has potential solely or in combination with other compounds to demethylate Wnt negative regulatory genes and possibly impact patient outcomes. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 101st Annual Meeting of the American Association for Cancer Research; 2010 Apr 17-21; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2010;70(8 Suppl):Abstract nr 4932.
World Medical Association condemns harassment of health workers in West Bank and Gaza
Authors: O. Dyer
Journal: BMJ (2002)

The World Medical Association last week condemned the targeting and harassment of health workers in the West Bank and Gaza Strip. Echoing comments from the International Committee of the Red Cross and the World Health Organization, the secretary general, Delon Human, said that the association would raise the issue at the United Nations later this month. Of particular concern, he said, was the risk of infection from unburied bodies.

Since the beginning of April, 28 Palestinian Red Crescent Society workers have been detained …
Acute medical beds could be cut.
Authors: P. J. Toghill
Journal: BMJ (1992)

infarction in 1988.For the 109 patients whose patients' health status or their satisfaction with SIR,-Those responsible for medical and surgical notes were available (less than half the number of their care.-emergencies will have read with astonishment and patients identified from the coronary care unit'sWe believe that audit is important and that its dismay the Audit Commission's recommendations records), the median delay in attending the accident lessons should be viewed primarily in a clinical to reduce the numbers of acute hospital beds.'" and emergency department was 240 minutes.The rather than a financial light.The complexities of
Reduced Incidence of Lower-Extremity Amputations in People With Diabetes in Scotland
Authors: Brian Kennon, Graham P. Leese, Lynda Cochrane, Helen Colhoun, Sarah Wild, Duncan Stang, Naveed Sattar, Donald Pearson, Robert S. Lindsay, Andrew D. Morris, Shona Livingstone, Matthew Young, John McKnight, Scott Cunningham
Journal: Diabetes Care (2012)

To establish the incidence of nontraumatic lower-extremity amputation (LEA) in people with diabetes in Scotland.This cohort study linked national morbidity records and diabetes datasets to establish the number of people with diabetes who underwent nontraumatic major and minor LEA in Scotland from 2004 to 2008.Two thousand three hundred eighty-two individuals with diabetes underwent a nontraumatic LEA between 2004 and 2008; 57.1% (n = 1,359) underwent major LEAs. The incidence of any LEA among persons with diabetes fell over the 5-year study period by 29.8% (3.04 per 1,000 in 2004 to 2.13 per 1,000 in 2008, P < 0.001). Major LEA rates decreased by 40.7% from 1.87 per 1,000 in 2004 to 1.11 per 1,000 in 2008 (P < 0.001).There has been a significant reduction in the incidence of LEA in persons with diabetes in Scotland between 2004 and 2008, principally explained by a reduction in major amputation.
The Lettsomian Lectures on Aseptic Surgery in Theory and Practice: Delivered on February 15th, 1904
Authors: C. B. Lockwood
Journal: BMJ (1904)

KN..HE literature of skin' disinfection, has already reached large proportions.One author has published an excellent volume -of two hundred and odd pages upon the subject.1So far as -can be judged no one can yet claim that his nmethod is perfect.M-uch depends upon the stringency of the test applied.It.eems clear that the use of soapand mehanical means cannot -disinfect the skin.2Itmerely diminishes theamountof' infection.s'This is an imnportant point, because somesur- geons seem to rely solely upon mechanical methods and' soap and water for the disinfetion of theirhands.There is no room for doubt that when the mechanical scrubbing with brushes and pumice stone and abundant soap and water is followed by absoluto alcohol or rectified spirit the chances of sterility aregreatly increased.Next when,as in Fiirbringer's anethod, these are followed by immersion in sublimate lotion, -