AN ARTICLE CONTRIBUTED TO AN ANNIVERSARY VOLUME IN HONOR OF DOCTOR JOSEPH HERSEY PRATT
Authors: HOWARD F. ROOT
Journal: Annals of Internal Medicine (1938)

Article1 January 1938AN ARTICLE CONTRIBUTED TO AN ANNIVERSARY VOLUME IN HONOR OF DOCTOR JOSEPH HERSEY PRATTTHE EFFECTS OF INSULIN HYPOGLYCEMIA UPON THE DIABETIC HEART IN CHILDREN AND YOUTH*HOWARD F. ROOT, M.D., F.A.C.P.HOWARD F. ROOT, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-11-7-1332 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptINTRODUCTIONThe possibility that harmful effects upon the heart may be produced in diabetic patients by the use of insulin has rested upon the occasional anginal attack after the administration of insulin to cardiac patients. Transitory changes in the electrocardiogram have been noted after the administration of insulin, suggesting some change in the heart muscle. It must be remembered that the injection of insulin into the body in a sufficient quantity to produce hypoglycemia, brings about changes, varying with the individual, the amount of insulin injected, the state of the counter-regulatory system, and undoubtedly other factors. When the blood sugar...Bibliography1. HADORN W: Untersuchungen über die Beeinflussung des Herzens durch Insulin und Hypoglykämie, Ztschr. f. klin. Med., 1936, cxxx, 643-659. Google Scholar2. DE CHATELPALISA AC: Das Elektrokardiogramm in schweren Hypoglykämischen, Klin. Wchnschr., 1935, xiv, 1784-1786. CrossrefGoogle Scholar3. LABARREHOUSSA JP: Kongr.-Zentralbl. f. d. ges. inn. Med., 1936, lxix, 198. LABARRE, J.: Diabete et insulinemie, 1933, Masson and Cie, Paris. Google Scholar4. SCHÖNBRUNNER H: Elektrokardiogramme einer 73 jahr Diabetikerin mit einem tiefen Q3 , Klin. Wchnschr., 1935, xv, 36. Google Scholar5. GIGON A: Insulin und Diabetesfragen, Klin. Wchnschr., 1923, xi, 1670-1678. Google Scholar6. MILLESSMITH GPW, Effects of epinephrine on the heart, Am. Heart Jr., 1937, xiv, 198. CrossrefGoogle Scholar7. DOUGLASGELFANDSHOOKHOFF AHBC: Production by epinephrine of S-T changes in the electrocardiograms of the cat, similar to those of coronary sclerosis, Am. Heart Jr., 1937, xiv. Google Scholar8. SOSKINKATZFRISCH SLNR: Dual action of insulin upon the heart, ANN. INT. MED., 1935, viii, 900-906. Google Scholar9. CRUICKSHANK EW: Cardiac metabolism, Physiol. Rev., 1936, xvi, 597-639. CrossrefGoogle Scholar10. HIMWICHGOLDFARBNAHUM HEWLG: Changes in carbohydrate metabolism of heart following coronary occlusion, Am. Jr. Physiol., 1934, cix, 403-408. CrossrefGoogle Scholar11. HIMWICHGOLDFARBFAZIKAS HEWJF: Carbohydrate metabolism of the heart during pancreas diabetes, Am. Jr. Physiol., 1936, cxiv, 273-278. Google Scholar12. BODO R: Effect of heart tonics on heart tone and coronary circulation, Jr. Physiol., 1928, lxiv, 365-387. CrossrefGoogle Scholar13. VISSCHERMULLER MBEA: Influence of insulin upon mammalian heart, Jr. Physiol., 1927, lxii, 341-348. CrossrefGoogle Scholar14. MARBLE A: Hypoglycemia due to insulin, N. E. Jr. Med., 1937, ccxvii, 130. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Boston, Massachusetts*Received for publication August 16, 1937. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByThe effects of insulin-induced hypoglycemia in patients with angina pectorisDegenerative vascular lesions and diabetes mellitus 1 January 1938Volume 11, Issue 7Page: 1332-1343KeywordsBlood sugarElectrocardiographyHypoglycemiaInsulinInsulin-like growth factorsMyocardium Issue Published: 1 January 1938 PDF DownloadLoading ...