Thrombotic Thrombocytopenic Purpura and Human T-Lymphotrophic Virus, Type 1 (HTLV-1)
Authors: Andrew C. Dixon, Denny W. Kwock, Jeffrey M. Nakamura, Eugene T. Yanagihara, Stanley M. Saiki, Anne J. Bodner, Steven S. Alexander
Journal: Annals of Internal Medicine (1989)

Letters and Corrections1 January 1989Thrombotic Thrombocytopenic Purpura and Human T-Lymphotrophic Virus, Type 1 (HTLV-1)Andrew C. Dixon, MD, Denny W. Kwock, Jeffrey M. Nakamura, MD, Eugene T. Yanagihara, MD, Stanley M. Saiki, MD, Anne J. Bodner, PhD, Steven S. Alexander, PhDAndrew C. Dixon, MDSearch for more papers by this author, Denny W. KwockSearch for more papers by this author, Jeffrey M. Nakamura, MDSearch for more papers by this author, Eugene T. Yanagihara, MDSearch for more papers by this author, Stanley M. Saiki, MDSearch for more papers by this author, Anne J. Bodner, PhDSearch for more papers by this author, Steven S. Alexander, PhDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-110-1-93 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editor: Several recent studies (1-4) have shown that thrombotic thrombocytopenic purpura can be a manifestation of infection with human immunodeficiency virus (HIV). Human T-lymphotrophic virus, type 1 (HTLV-1), is a retrovirus from the same family as HIV. We report the first known case of thrombotic thrombocytopenic purpura in a patient with HTLV-1 infection.A 55-year-old man, born in Hawaii of southern Japanese ancestry, was hospitalized for weakness, fevers, and a right orbital ecchymosis. He had otherwise been healthy and denied travel outside of Hawaii, previous transfusions, or intravenous drug use. At admission, the patient was febrile but otherwise...References1. Jokela J, Flynn T, and Henry K. Thrombotic thrombocytopenic purpura in a human immunodeficiency virus (HIV)-seropositive homosexual man. Am J Hematol. 1987;25:341-3. CrossrefMedlineGoogle Scholar2. Leaf A, Laubenstein L, Raphael B, Hochster H, Baez L, and Karpatkin S. Thrombotic thrombocytopenic purpura associated with human immunodeficiency virus type 1 (HIV-1) infection. Ann Intern Med. 1988;109:194-7. LinkGoogle Scholar3. Nair J, Bellevue R, Bertoni M, and Dosik H. Thrombotic thrombocytopenic purpura in patients with the acquired immunodeficiency syndrome (AIDS)-related complex: a report of two cases. Ann Intern Med. 1988;109:209-12. LinkGoogle Scholar4. Botti A, Hyde P, and DiPillo F. Thrombotic thrombocytopenic purpura in a patient who subsequently developed the acquired immunodeficiency syndrome (AIDS). Ann Intern Med. 1988;109:242-3. LinkGoogle Scholar5. Ito Y. The epidemiology of human T-cell leukemia/lymphoma virus. Curr Topics Microbiol Immunol. 1985;115:99-112. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: Andrew C. Dixon, MD; Denny W. Kwock; Jeffrey M. Nakamura, MD; Eugene T. Yanagihara, MD; Stanley M. Saiki, MD; Anne J. Bodner, PhD; Steven S. Alexander, PhD PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byMap of thrombogenesis in viral infections and viral-driven tumoursViral-associated thrombotic microangiopathiesHUMAN RETROVIRUSESTreatment of Thrombotic Thrombocytopenic Purpura with the Cryosupernatant Fraction of Plasma: A Case Report and Review of the LiteratureTreatment of Thrombotic Thrombocytopenic Purpura with the Cryosupernatant Fraction of Plasma: A Case Report and Review of the LiteratureIs it necessary to test patients with immune thrombocytopenic purpura (ITP) for seropositivity to HTLV-1?On the etiology of tropical spastic paraparesis and human T-cell lymphotropic virus I-—Associated myelopathyIdentification of human t cell leukemia/lymphoma virus type i antibodies, dna, and protein in patients with polymyositisRetroviruses and Their Roles in Chronic Inflammatory Diseases and AutoimmunityThrombotic microangiopathy and retroviral infections: A 13-year experienceImmunologic thrombocytopenia followed by thrombotic thrombocytopenic purpura in two HIV1 patientsAttitude pratique devant la découverte d'une sérologie HTLV-I/II positive chez un donneur de sangThrombotic Thrombocytopenic Purpura Causing Sudden, Unexpected Death—A Series of Eight PatientsThrombotic MicroangiopathyPotential Role of Human T-cell Leukemia/Lymphoma Viruses (HTLV) in Diseases Other Than Acute T-cell Leukemia/Lymphoma (ATL) 1 January 1989Volume 110, Issue 1Page: 93-94KeywordsDrugsFeversHIVHIV infectionsRetrovirusesThrombotic thrombocytopenic purpura ePublished: 1 December 2008 Issue Published: 1 January 1989 PDF downloadLoading ...