Association of Hepatitis C and Diabetes Mellitus
Authors: Shruti H. Mehta, Mark S. Sulkowski, David L. Thomas
Journal: Annals of Internal Medicine (2001)

Letters17 July 2001Association of Hepatitis C and Diabetes MellitusShruti H. Mehta, MPH, Mark S. Sulkowski, MD, and David L. Thomas, MD, MPHShruti H. Mehta, MPHJohns Hopkins University School of Public Health Baltimore, MD 21201 (Mehta, Sulkowski, Thomas)Search for more papers by this author, Mark S. Sulkowski, MDJohns Hopkins University School of Public Health Baltimore, MD 21201 (Mehta, Sulkowski, Thomas)Search for more papers by this author, and David L. Thomas, MD, MPHJohns Hopkins University School of Public Health Baltimore, MD 21201 (Mehta, Sulkowski, Thomas)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-135-2-200107170-00018 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:We agree with Drs. Knobler and Schattner that histologic examination of the liver in HCV-infected persons with and without type 2 diabetes mellitus contributes to our understanding of the relationship between these conditions. Previous studies have demonstrated that community-identified HCV infection is not usually associated with cirrhosis (1). Thus, we would not anticipate finding a high prevalence of cirrhosis among HCV-infected persons identified in a community setting, such as the participants in NHANES III. While this could not be confirmed in our analysis because liver biopsies were not performed in NHANES, the assumption is supported by a study ...References1. Rodger A, Roberts S, Lanigan A, Bowden S, Brown T, Crofts N. Assessment of long-term outcomes of community-acquired hepatitis C infection in a cohort with sera stored from 1971 to 1975. Hepatology. 2000;32:582-7. [PMID: 10960453] CrossrefMedlineGoogle Scholar2. Knobler H, Schihmanter R, Zifroni A, Fenakel G, Schattner A. Increased risk of type 2 diabetes in noncirrhotic patients with chronichepatitis C virus infection. Mayo Clin Proc. 2000;75:355-9. [PMID: 10761489] CrossrefMedlineGoogle Scholar3. Labropoulou-Karatza C, Goritsas C, Fragopanagou H, Repandi M, Matsouka P, Alexandrides T. High prevalence of diabetes mellitus among adult β-thalassaemic patients with chronic hepatitis C. Eur J Gastroenterol Hepatol. 1999;11:1033-6. [PMID: 10503842] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Shruti H. Mehta, MPH; Mark S. Sulkowski, MD; David L. Thomas, MD, MPHAffiliations: Johns Hopkins University School of Public Health Baltimore, MD 21201 (Mehta, Sulkowski, Thomas) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoPrevalence of Type 2 Diabetes Mellitus among Persons with Hepatitis C Virus Infection in the United States Shruti H. Mehta , Frederick L. Brancati , Mark S. Sulkowski , Steffanie A. Strathdee , Moyses Szklo , and David L. Thomas Association of Hepatitis C and Diabetes Mellitus Hilla Knobler and A. Schattner Association of Hepatitis C and Diabetes Mellitus Robert Paris Metrics 17 July 2001Volume 135, Issue 2Page: 142KeywordsBiopsyCirrhosisDiabetes mellitusFerritinHepatitis CInflammationLiverOdds ratioSerum ferritin levelsType 2 diabetes ePublished: 17 July 2001 Issue Published: 17 July 2001 Copyright & PermissionsCopyright © 2001 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...