Colonic Bacillary Angiomatosis
Authors: Young B. Huh
Journal: Annals of Internal Medicine (1996)

Brief Communications15 April 1996Colonic Bacillary AngiomatosisYoung B. Huh, MD, Suzanne Rose, MD, Robert E. Schoen, MD, MPH, Susan Hunt, MD, David C. Whitcomb, MD, PhD, and Sydney Finkelstein, MDYoung B. Huh, MDFrom the University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.Search for more papers by this author, Suzanne Rose, MDFrom the University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.Search for more papers by this author, Robert E. Schoen, MD, MPHFrom the University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.Search for more papers by this author, Susan Hunt, MDFrom the University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.Search for more papers by this author, David C. Whitcomb, MD, PhDFrom the University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.Search for more papers by this author, and Sydney Finkelstein, MDFrom the University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-124-8-199604150-00005 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Bacillary angiomatosis is an infectious disease caused by small, fastidious, gram-negative bacilli known as Bartonella henselae and B. quintana (formerly Rochalimaea henselae and R. quintana) [1]. The infection is characterized by a vascular proliferation of the skin or visceral organs and usually occurs in immunosuppressed patients [2].Cutaneous bacillary angiomatosis is the most common clinical form of bacillary angiomatosis. Skin lesions present as red papules, subcutaneous nodules, or cellulitic plaques [2-4]. Bartonella infection has also been seen in the lymph nodes, liver (bacillary peliosis hepatis), spleen, bone, heart, central nervous system, oropharynx, larynx, endobronchus, duodenum, and blood [3-5].We report ...References1. Brenner DJ, O'Connor SP, Winkler HH, Steigerwalt AG. Proposals to unify the genera Bartonella and Rochalimaea, with descriptions of Bartonella quintana comb. nov., Bartonella vinsonii comb. nov., Bartonella henselae comb. nov., and Bartonella elizabethae comb. nov., and to remove the family Bartonellaceae from the order Richettsiales. Int J Syst Bacteriol. 1993; 43:777-86. Google Scholar2. Cockerell CJ, Whitlow MA, Webster GF, Friedman-Kien AE. Epithelioid angiomatosis: a distinct vascular disorder in patients with the acquired immunodeficiency syndrome or AIDS-related complex. Lancet. 1987; 2:654-6. Google Scholar3. Adal KA, Cockerell CJ, Petri WA Jr. Cat scratch disease, bacillary angiomatosis, and other infections due to Rochalimaea. N Engl J Med. 1994; 330:1509-15. Google Scholar4. Koehler JE, Quinn FD, Berger TG, LeBoit PE, Tappero JW. Isolation of Rochalimaea species from cutaneous and osseous lesions of bacillary angiomatosis. N Engl J Med. 1992; 327:1625-31. Google Scholar5. Walford N, Van der Wouw PA, Das PK, Ten Velden JJ, Hulsebosch HJ. Epithelioid angiomatosis in the acquired immunodeficiency syndrome: morphology and differential diagnosis. Histopathology. 1990; 16:83-8. Google Scholar6. Stoler MH, Bonfiglio TA, Steigbigel RT, Pereira M. An atypical subcutaneous infection associated with acquired immune deficiency syndrome. Am J Clin Pathol. 1983; 80:714-8. Google Scholar7. Koehler JE, Cederberg L. Intra-abdominal mass associated with gastrointestinal hemorrhage: a new manifestation of bacillary angiomatosis. Gastroenterology. 1996; 109:2011-4. Google Scholar8. Cockerell CJ, Tierno PM, Friedman-Klein AE, Kim KS. Clinical, histologic, microbiologic, and biochemical characterization of the causative agent of bacillary (epithelioid) angiomatosis: a rickettsial illness with features of bartonellosis. J Invest Dermatol. 1991; 97:812-7. Google Scholar9. Garcia FU, Wojta J, Broadley KN, Davidson JM, Hoover RL. Bartonella bacilliformis stimulates endothelial cells in vitro and is angiogenic in vivo. Am J Pathol. 1990; 136:1125-35. Google Scholar10. Conley T, Slater L, Hamilton K. Rochalimaea species stimulate human endothelial cell proliferation and migration in vitro. J Lab Clin Med. 1994; 124:521-8. Google Scholar11. Grishman MB, Granger DN. Neutrophil-mediated mucosal injury. Role of reactive oxygen metabolites. Dig Dis Sci. 1988; 33(3 Suppl):6S-15S. Google Scholar12. Schreiber S, MacDermott RP, Raedler A, Pinnau R, Bertovich MJ, Nash GS. Increased activation of isolated intestinal lamina propria mononuclear cells in inflammatory bowel disease. Gastroenterology. 1991; 101:1020-30. Google Scholar13. James SP. Remission of Crohn's disease after human immunodeficiency virus infection. Gastroenterology. 1988; 95:1667-9. Google Scholar Author, Article, and Disclosure InformationAffiliations: From the University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.Corresponding Author: Suzanne Rose, MD, University of Pittsburgh Medical Center, Division of Gastroenterology and Hepatology, 200 Lothrop Street, Mezzanine Level, C Wing, Presbyterian University Hospital, Pittsburgh, PA 15213.Current Author Addresses: Drs. Huh, Rose, Schoen, and Whitcomb: University of Pittsburgh Medical Center, Division of Gastroenterology and Hepatology, 200 Lothrop Street, Mezzanine Level, C Wing, Presbyterian University Hospital, Pittsburgh, PA 15213. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byMulti-organ involvement of bacillary angiomatosis masquerading as Kaposi sarcoma and pyogenic granuloma: A case report and literature reviewAn unusual case of bacillary angiomatosis in the oral cavity of an AIDS patient who had no concomitant tegumentary lesions – case report and reviewBartonella, Including Cat-Scratch DiseaseSmall, Nondescript Ulcers With an Uncommon EtiologyBacillary Angiomatosis in an Immunocompetent Child: A Case Report and Review of the LiteratureBartonella, Including Cat-Scratch DiseaseUpper Gastrointestinal Bacillary Angiomatosis Causing Hematemesis: A Case ReportGut Infections: Etiopathogenetic and Clinical RemarksBacillary angiomatosis: description of 13 cases reported in five reference centers for AIDS treatment in Rio de Janeiro, BrazilDiagnosis and Treatment of Colonic Disease in AIDSBacillary angiomatosis and other Bartonella species infectionsBacillary angiomatosis: presentation of six patients, some with unusual featuresBacillary angiomatosis: presentation of six patients, some with unusual featuresClinical Aspects of Bartonella Infections 15 April 1996Volume 124, Issue 8Page: 735-737KeywordsAIDSAngiomatosisBartonellaBiopsyColonDiarrheaInflammatory bowel diseaseMucous membranesStainingUlcers ePublished: 15 August 2000 Issue Published: 15 April 1996 Copyright & PermissionsCopyright © 1996 by American College of Physicians. 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