Management of Antibiotic-Resistant Neisseria gonorrhoeae
Authors: Franklyn N. Judson
Journal: Annals of Internal Medicine (1989)

Editorials1 January 1989Management of Antibiotic-Resistant Neisseria gonorrhoeaeFranklyn N. Judson, MDFranklyn N. Judson, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-110-1-5 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptBecause man is the only natural host of the species Neisseria gonorrhoeae, the ability of the gonococcus to thrive in a hostile antibiotic world serves as testimony both to the genetic principles of natural selection and to the unwillingness of its human host to limit sexual contacts to long-term mutually monogamous relationships.From 1945 to 1954, the first decade that penicillin was used to treat gonorrhea, antimicrobial resistance and treatment failures were extremely rare. Even the smallest doses of penicillin, tetracycline, or chloramphenicol eradicated the helpless gonococcus, and a movement by ecologists of the day to placeN. gonorrhoeaeon...References1. MartinLesterPriceSchmale JAEJ. Comparative study of gonococcal susceptibility to penicillin in the United States, 1955-1969. J Infect Dis. 1970;122:459-61. CrossrefMedlineGoogle Scholar2. ReynoldsZaidiThornsberry GAC. The National Gonorrhea Therapy Monitoring Study. II. Trends and seasonality of antibiotic resistance of Neisseria gonorrhoeae. Sex Transm Dis. 1979;6(Suppl.):103-11. CrossrefMedlineGoogle Scholar3. FarukiKohmescherMcKinneySparling HRWP. A community-based outbreak of infection with penicillin-resistant Neisseria gonorrhoeae not producing penicillinase (chromosomally mediated resistance). N Engl J Med. 1985;313:607-11. CrossrefMedlineGoogle Scholar4. RiceBiddleJean LouisDeWittBlountMorse RJYWJS. 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Author, Article, and Disclosure InformationAffiliations: University of Colorado and Denver Disease Control Service Denver, Colorado PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByGonococia genital femeninaMolecular Epidemiology of Infections With Neisseria gonorrhoeae Among Visitors to a Sexually Transmitted Diseases ClinicAntimicrobial Susceptibility and Types of Neisseria gonorrhoeae in GreeceG UINEA -B ISSAU'S P LANTS: IN VITRO S USCEPTIBILITY S TUDIES ON N EISSERIA GONORRHOEAEAntibiotic use in the emergency department. 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