Chagasic Encephalitis as the Initial Manifestation of AIDS
Authors: Nathan Lambert, Brijesh Mehta, Ruth Walters, Joseph J. Eron
Journal: Annals of Internal Medicine (2006)

Letters20 June 2006Chagasic Encephalitis as the Initial Manifestation of AIDSNathan Lambert, MD, Brijesh Mehta, MD, Ruth Walters, MD, and Joseph J. Eron, MDNathan Lambert, MDFrom the University of North Carolina, Chapel Hill, NC 27599., Brijesh Mehta, MDFrom the University of North Carolina, Chapel Hill, NC 27599., Ruth Walters, MDFrom the University of North Carolina, Chapel Hill, NC 27599., and Joseph J. Eron, MDFrom the University of North Carolina, Chapel Hill, NC 27599.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-144-12-200606200-00018 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Background: Late presentation to care remains common in patients with HIV infection, even in developed countries (1). A patient presenting with neurologic symptoms who has multiple ring-enhancing lesions, a low CD4 cell count, and positive results on serologic tests for Toxoplasma gondii would be presumptively treated for toxoplasmosis encephalitis.Objective: To describe a case of chagasic meningoencephalitis in a patient with previously undiagnosed AIDS.Case Report: A previously healthy, 56-year-old heterosexual man presented to the emergency department for progressive leg weakness, malaise, and urinary retention that began 3 weeks earlier. He was originally from southern Mexico but had lived in ...References1. Sabin CA, Smith CJ, Gumley H, Murphy G, Lampe FC, Phillips AN, et al. Late presenters in the era of highly active antiretroviral therapy: uptake of and responses to antiretroviral therapy. AIDS. 2004;18:2145-51. [PMID: 15577647] CrossrefMedlineGoogle Scholar2. Gay CL, Napravnik S, Eron JJ. Advanced immunosuppression at entry to HIV care in the southeastern United States and associated risk factors. AIDS. 2006;20:775-8. [PMID: 16514310] CrossrefMedlineGoogle Scholar3. Vaidian AK, Weiss LM, Tanowitz HB. Chagas' disease and AIDS. Kinetoplastid Biol Dis. 2004;3:2. [PMID: 15142278] CrossrefMedlineGoogle Scholar4. Rivera J, Hillis LD, Levine BD. Reactivation of cardiac Chagas' disease in acquired immune deficiency syndrome. Am J Cardiol. 2004;94:1102-3. [PMID: 15476640] CrossrefMedlineGoogle Scholar5. Yoo TW, Mlikotic A, Cornford ME, Beck CK. Concurrent cerebral American trypanosomiasis and toxoplasmosis in a patient with AIDS. Clin Infect Dis. 2004;39:30-4. [PMID: 15356839] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From the University of North Carolina, Chapel Hill, NC 27599.Disclosures: None disclosed. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByUnusual Brain Lesions Diagnosed From a Cerebrospinal Fluid Wet Preparation in a Patient With AIDSChagas Disease in the United States: a Public Health ApproachCerebral Trypanosomiasis in an Immunocompromised Patient: Case Report and Review of the LiteratureSymptomatic profile of infected individuals with HIV/AIDS in a physiotherapy departmentA coinfecção T. cruzi/HIV em regiões não endêmicas para a doença de chagasTrypanosoma cruzi Meningoencephalitis in a Patient with Acquired Immunodeficiency SyndromePerfil epidemiológico dos indivíduos HIV positivo e coinfecção HIV-Leishmania em um serviço de referência em São Luís, MA, BrasilAmerican trypanosomiasisCo-infection Trypanosoma cruzi/HIV: systematic review (1980 - 2010)American Trypanosomiasis (Chagas Disease) * *All the material in this chapter is in the public domain, with the exception of the borrowed figures.Trypanosoma Species (American Trypanosomiasis, Chagas' Disease)TRYPANOSOMIASISTropical NeurologyNeuroinfecção humana por Trypanosoma cruziReactivation of Chagas disease with central nervous system involvement in HIV-infected patients in Argentina, 1992–2007Fever of Unknown Origin Due to ZoonosesEtiological treatment of chronic Chagas disease: neglected 'evidence' by evidence-based medicine 20 June 2006Volume 144, Issue 12Page: 941-943KeywordsBiopsyBrainCentral nervous systemChagas diseaseEncephalitisLesionsMagnetic resonance imagingSpinal cordToxoplasmosisTrypanosoma cruzi ePublished: 20 June 2006 Issue Published: 20 June 2006 CopyrightCopyright © 2006 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...