Succinylcholine-Induced Hyperkalemia Complicating the Neuroleptic Malignant Syndrome
Authors: Alfred L. George, Charles A. Wood
Journal: Annals of Internal Medicine (1987)

Letters and Corrections1 January 1987Succinylcholine-Induced Hyperkalemia Complicating the Neuroleptic Malignant SyndromeALFRED L. GEORGE JR., M.D., CHARLES A. WOOD JR., Pharm.D.ALFRED L. GEORGE JR., M.D., CHARLES A. WOOD JR., Pharm.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-106-1-172_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Severe hyperkalemia may complicate the use of succinylcholine in patients with major burns, direct muscle trauma, and various neuromuscular disorders (1-3). Nontraumatic rhabdomyolysis is common in the neuroleptic malignant syndrome (4) but has not been recognized as a risk factor for succinylcholine-induced hyperkalemia. We present the case of a patient with the neuroleptic malignant syndrome complicated by massive rhabdomyolysis in whom life-threatening hyperkalemia developed after the administration of intravenous succinylcholine.A 28-year-old white man was admitted for treatment of chronic back pain complicated by habitual narcotic and diazepam use. He had received succinylcholine during lumbar laminectomy three...References1. AZAR I. The response of patients with neuromuscular disorders to muscle relaxants: a review. Anesthesiology. 1984;61:173-87. CrossrefMedlineGoogle Scholar2. MAZZEESCUEHOUSTON RHJ. Hyperkalemia and cardiovascular collapse following administration of succinylcholine to the traumatized patient. Anesthesiology. 1969;31:540-7. CrossrefMedlineGoogle Scholar3. BIRCHMITCHELLPLAYFORDLANG AGGC. Changes in serum potassium response to succinylcholine following trauma. JAMA. 1969;210:490-3. CrossrefMedlineGoogle Scholar4. GUZEBAXTER BL. Neuroleptic malignant syndrome. N Engl J Med. 1985;313:163-6. CrossrefMedlineGoogle Scholar5. LOTSTRALINKOWSKIMENDLEWICZ FPJ. General anesthesia after neuroleptic malignant syndrome. Biol Psychiatry. 1983;18:243-7. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Saint Thomas Hospital Vanderbilt University Medical Center Nashville, TN 37232 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byNeuroleptic Malignant SyndromeElectroconvulsive Therapy for Neuroleptic Malignant SyndromeNeuroleptic Malignant SyndromeExtrarenal Potassium MetabolismExtrarenal Potassium MetabolismCatatonia and Prediction of Response to Electroconvulsive TherapyNeuropsychiatric Sequelae of Neuroleptic Malignant SyndromeTHE NEUROLEPTIC MALIGNANT AND SEROTONIN SYNDROMESTreatment of Neuroleptic Malignant SyndromeElectroconvulsive treatment of neuroleptic malignant syndrome: a review and report of casesElectroconvulsive Treatment of Neuroleptic Malignant Syndrome: A Review and Report of CasesRepeated propofol anesthesia for a patient with a history of neuroleptic malignant syndrome.Succinylcholine-induced Hyperkalemia Following Prolonged Pharmacologic Neuromuscular BlockadeNeuroleptic malignant syndrome and mivacurium: a safe alternative to succinylcholine?HYPERTHERMIA AND NEUROLEPTIC MALIGNANT SYNDROMEMyeloma and benign intracranial hypertension: Author's replyMissed neuroleptic malignant syndrome.Missed neuroleptic malignant syndrome.Missed neuroleptic malignant syndrome.Missed neuroleptic malignant syndrome: Authors' replySuxamethonium and HyperkalaemiaNeuroleptic malignant syndrome: a case for electroconvulsive therapy. 1 January 1987Volume 106, Issue 1Page: 172-172KeywordsAntipsychoticsBurnsDiazepamLaminectomyLower back painMedical risk factorsMusclesRhabdomyolysis Issue Published: 1 January 1987 PDF downloadLoading ...