Prostaglandins: Newest of the Hormones?
Authors: NATOO PATEL
Journal: Annals of Internal Medicine (1970)

Editorial1 September 1970Prostaglandins: Newest of the Hormones?NATOO PATEL, M.D.NATOO PATEL, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-73-3-483 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn recent years a unique group of chemically closely related compounds—the prostaglandins—have appeared on the medical horizon. Because of their ability to affect a host of physiological functions they appear to have potential value in a wide variety of clinical conditions. Research in progress spans many countries and hundreds of centers and includes studies on the cardiovasculorenal system (blood pressure, water and electrolyte excretion), the female and male reproductive systems (the induction of labor and therapeutic abortion and antifertility and fertility), the pulmonary system (bronchodilation), the upper respiratory system (nasal patency), and the gastrointestinal system (gastric antisecretory activity).Euler (1)...References1. EULER U: On the specific vasodilating and plain muscle stimulating substances from accessory genital glands in man and certain animals (prostaglandin and vesiglandin). J Physiol 88:213-234, 1936 CrossrefMedlineGoogle Scholar2. BERGSTRÖMSJÖVALL SJ: The isolation of prostaglandin F (and prostaglandin E) from sheep prostate glands. Acta Chem Scand 14:1693-1700 (1701), 1960 CrossrefGoogle Scholar3. DORPBEERTHUISNUGTEREN DRD: The biosynthesis of prostaglandins. 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BYGDEMAN M: Prostaglandins in human seminal fluid and their correlation to fertility, Int J Fert 14:228-231, 1969 MedlineGoogle Scholar23. ROSENTHALEDERVINISBEGANY MAA: Bronchodilator activity of the prostaglandin PGE2. Pharmacologist 10:175, 1968 Google Scholar24. CUTHHERT M: Effect on airways resistance of prostaglandin E1 administered to healthy and asthmatic volunteers. Brit Med J 4:723-726, 1969 CrossrefMedlineGoogle Scholar25. JACKSONTURNER RJ: Constriction of human nasal blood vessels with prostaglandin (PGE1), in Abstracts of the 4th International Congress of Pharmacology. Basel, 14-18 July, 1969, p. 385 Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: The Upjohn Co. Kalamazoo, Mich. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByCardiac output response to prostaglandin E2-induced abortion in the second trimesterMaternal cardiovascular adjustments to pregnancyReferencesThe ProstaglandinsDeveloping applications of prostaglandins in obstetrics and gynecology 1 September 1970Volume 73, Issue 3Page: 483-485KeywordsBlood pressureExcretionGenital anatomyHormonesLabor and deliveryProstaglandinsReproductive systemRespiratory systemVentilators Issue Published: 1 September 1970 PDF DownloadLoading ...