Celiac Disease
Authors: D. J. BUCHAN
Journal: Annals of Internal Medicine (1962)

Article1 July 1962Celiac DiseaseProblems in Diagnosis and Effects of a Gluten Free DietD. J. BUCHAN, M.D., F.R.C.P.(C), J. W. GERRARD, D.M., M.R.C.P.(L), F.R.C.P.(C)D. J. BUCHAN, M.D., F.R.C.P.(C)Search for more papers by this author, J. W. GERRARD, D.M., M.R.C.P.(L), F.R.C.P.(C)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-57-1-85 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTwo recent advances in the knowledge of celiac disease have resulted in greatly increased interest in this disease. The first was the demonstration of the role of wheat gluten in producing steatorrhea in celiac children (1) and the subsequent use of a gluten free diet in the successful treatment of this disease in children and of idiopathic steatorrhea or non-tropical sprue in the adult (2-5). The response of patients with idiopathic steatorrhea to a gluten free diet suggests a similarity between the 2 diseases and, indeed, some think them to be identical and call non-tropical sprue or idiopathic steatorrhea adult...References1. DICKE WK: Coeliake, thesis, Utrecht, 1955. Google Scholar2. FRENCHHAWKINSSMITH JMCFN: The effect of a wheat gluten free diet in adult idiopathic steatorrhea. Quart. J. Med. 26: 481, 1957. MedlineGoogle Scholar3. FINLAYWIGHTMAN JMKJ: Modern treatment of the malabsorption syndrome in adults. Ann. Intern. Med. 45: 191, 1956. LinkGoogle Scholar4. BUCHANMARKOGERRARD DJAJJW: The malabsorption syndrome: its treatment with a gluten free diet. Canad. Med. Ass. J. 79: 227, 1958. MedlineGoogle Scholar5. SLEISENGER MH: Clinical and metabolic studies in non-tropical sprue. New Engl. J. Med. 265: 49, 1961. CrossrefGoogle Scholar6. SHINER M: Duodenal and jejunal biopsies. I. A discussion of the method, its difficulties, and applications. Gastroenterology 33: 64, 1957. CrossrefMedlineGoogle Scholar7. RUBINBRANDBORGPHELPSTAYLOR CELLPCHC: Studies of celiac disease. I. Apparent identical and specific nature of duodenal and proximal jejunal lesion in celiac disease and idiopathic sprue. Gastroenterology 38: 28, 1960. CrossrefMedlineGoogle Scholar8. SHINERDONIACH MI: Histopathologic studies in steatorrhea. Gastroenterology 38: 419, 1960. CrossrefMedlineGoogle Scholar9. BRANDBORGRUBINQUINTON LLCEWE: A multipurpose instrument for suction biopsy of the esophagus, stomach, small bowel and colon. Gastroenterology 37: 1, 1959. CrossrefMedlineGoogle Scholar10. BOSSAKWANGADLERSBERG ETCID: Clinical aspects of the malabsorption syndrome, in The Malabsorption Syndrome, ed. by Adlersberg, D., Grune & Stratton, Inc., New York, 1957. Google Scholar11. GIRDWOODDELAMOREWILLIAMS RHIWAW: Jejunal biopsy in malabsorptive disorders of the adult. Brit. Med. J. 1: 319, 1961. CrossrefMedlineGoogle Scholar12. BADENOCH J: Steatorrhea in the adult. Brit. Med. J. 2: 879, 1960. CrossrefMedlineGoogle Scholar13. WANGBOSSAK CIET: Hemorrhagic manifestations in idiopathic sprue. J. Mount Sinai Hosp. N. Y. 24: 317, 1957. MedlineGoogle Scholar14. MOORESTRICKLANDPRICHARD MJWHRW: Sprue with bleeding from hypoprothrombinemia. Arch. Intern. Med. 97: 814, 1956. CrossrefGoogle Scholar15. COOKEPEENEYHAWKINS WTALCF: Symptoms, signs, and diagnostic features of idiopathic steatorrhea. Quart. J. Med. 22: 59, 1953. MedlineGoogle Scholar16. SENCER W: Neurologic manifestations in the malabsorption syndrome. J. Mount Sinai Hosp. N. Y. 24: 331, 1957. MedlineGoogle Scholar17. HARTLEY J: Osseous changes and fractures in the malabsorption syndrome. J. Mount Sinai Hosp. N. Y. 24: 346, 1957. MedlineGoogle Scholar18. JUERGENS JL: Severe osteomalacia associated with occult steatorrhea due to non-tropical sprue. Arch. Intern. Med. 98: 774, 1956. CrossrefGoogle Scholar19. SHAW S: Idiopathic steatorrhea and hemorrhage due to malabsorption of vitamin K. Brit. Med. J. 2: 647, 1960. CrossrefMedlineGoogle Scholar20. SPITZERRYAN RJA: Belated diagnosis of steatorrhea. Canad. Med. Ass. J. 85: 656, 1961. MedlineGoogle Scholar21. FONEMEYNELLHARRISCOOKEBREWERCOX DJMJELWTDBEV: Jejunal biopsy in adult celiac disease and allied disorders. Lancet 1: 933, 1960. CrossrefMedlineGoogle Scholar22. CARTERSHELDENWALKER DWC: Inheritance of celiac disease. Ann. Hum. Genet. 23: 266, 1959. CrossrefMedlineGoogle Scholar23. RUBINBRANDBORGPHELPSTAYLORMURRAYSTEMLERHOWRYVOLWILER CELLPCHCCVRCW: Studies of celiac disease. II. The apparent irreversibility of the proximal intestinal pathology in celiac disease. Gastroenterology 38: 517, 1960. CrossrefMedlineGoogle Scholar24. RUBIN CE: Malabsorption: celiac sprue, in Annual Review of Medicine, ed. by Ryland, D. A., and Creger, W. P., Annual Reviews, Inc., Palo Alto, 1961, p. 51. CrossrefGoogle Scholar25. SHINERBIRBECK MMS: The micro villi of the small intestinal surface epithelium in celiac disease and in idiopathic steatorrhea. Gut 2: 277, 1961. CrossrefMedlineGoogle Scholar26. FETTERQUISTHENDRIX HTR: Preliminary note on ultrastructural abnormality of intestinal epithelium in adult celiac disease (non-tropical sprue) which is reversed by gluten free diet. Bull. Johns Hopkins Hosp. 106: 240, 1960. MedlineGoogle Scholar27. RUBIN CE: Celiac disease and idiopathic sprue. Gastroenterology 39: 260, 1960. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: D. J. BUCHAN, M.D., F.R.C.P.(C); J. W. GERRARD, D.M., M.R.C.P.(L), F.R.C.P.(C)Affiliations: Saskatoon,From the Departments of Medicine and Pediatrics, University of Saskatchewan and University Hospital, Saskatoon, Saskatchewan, Canada.Requests for reprints should be addressed to D. J. Buchan, M.D., Department of Medicine, University Hospital, University of Saskatchewan, Saskatoon, Saskatchewan, Canada. 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BOLT, M.D., F.A.C.P., J. ANTHONY PARRISH, M.B., M.R.C.P., ARTHUR B. FRENCH, M.D., F.A.C.P., H. MARVIN POLLARD, M.D., F.A.C.P. 1 July 1962Volume 57, Issue 1Page: 85-95KeywordsBiopsyCalciumCeliac diseaseChildrenDietExcretionGlutenHemoglobinHospital medicinePediatrics ePublished: 1 December 2008 Issue Published: 1 July 1962 PDF downloadLoading ...