tbuckley/cabot-search huggingface dataset:
Breast cancer screening guidelines agreed on by AMA, other medically related organizations
Authors: C. Gordillo
Journal: JAMA (1989)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Recognising serious illness in feverish young children in primary care
Authors: Anthony Harnden
Journal: BMJ (2007)

Increasing the opportunity for prompt clinical assessment is the priority

The diagnosis and management of children with fever is an important part of primary care. Parents and children put their trust in general practitioners, who rightly worry about making a correct judgment. Although general practitioners have substantial clinical experience of assessing febrile children, half of children with meningococcal disease are sent home at first primary care consultation.1 How can this be and what can we do to improve our assessment of febrile children?

Several diagnostic difficulties face us. Firstly, serious bacterial infection in children is now rare. The successful introduction of Haemophilus influenzae type B and meningococcal C vaccines into the UK childhood immunisation schedule has led to a dramatic reduction in the prevalence of invasive infections caused by these organisms.2 3 Early reports suggest that the recently introduced conjugate pneumococcal vaccine will do the same.4 Studies have reported a large variation in estimated incidences of invasive bacterial disease in preschool children, but the quoted 1%5 is almost certainly now a …
Glimpses of the Past from the Recently Unearthed Ancient Corpses in China
Authors: TSUNG O. CHENG
Journal: Annals of Internal Medicine (1984)

Abroad1 November 1984Glimpses of the Past from the Recently Unearthed Ancient Corpses in ChinaTSUNG O. CHENG, M.D.TSUNG O. CHENG, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-101-5-714 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptDuring the last decade several ancient corpses were unearthed in China; almost all of them were discovered accidently during excavation at construction sites. The excavated bodies of persons who died over 2000 years ago astonished scientists throughout the world, because all of the bodies were extremely well preserved. This preservation through more than 2000 years was believed to result from the combined effects of hermetic sealing and the deliberate deep burying of the coffins in the suitable geological and hydrological environments of the burial grounds. The Chinese government dispatched many pathologists, anatomists, biochemists, radiologists, and other medical specialists from all...References1. HALL A. A lady from China's past. Natl Geogr. 1974;145:661-81. Google Scholar2. WUTIANZENG ZHY. Study of the ancient corpse of the Western Han Dynasty unearthed from tomb no. 168 on Phoenix Hill at Jiangling County (a comprehensive report). Med Bull Wuhan Med Coll. 1980;1:1-8. Google Scholar3. CHENG T. Recent development in cardiology. Chin Med J. 1983;96:499-506. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: The George Washington University Medical Center Washington, D.C. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByPulcer disease in womenMummies in China: Mawangdui and Other Related MummiesMummies in China: Mawangdui and Other Related MummiesTwo findings of gallstones in archaeological mummies from ColombiaMummification in Korea and China: Mawangdui, Song, Ming and Joseon Dynasty MummiesÚlcera péptica perforada: ¿es la forma de la metanfetamina conocida como “cristal” un nuevo factor de riesgo?Early History of Dyspepsia and Peptic Ulcer in the United StatesAnimal helminths in human archaeological remains: a review of zoonoses in the pastHuman intestinal parasites in the past: new findings and a reviewA modified surgical technique for the emergent treatment of giant ulcers concomitant with hemorrhage in the posterior wall of the duodenal bulbHippocrates, cardiology, Confucius and the Yellow EmperorLaparoscopic VagotomyGastric carcinomaSurgery for peptic ulcer diseaseSchistosomiasis: Immunological, Serological and Clinical AspectsGastric ulcerGraft disease in patients with coronary bypass grafting 1 November 1984Volume 101, Issue 5Page: 714-715KeywordsPathologistsRadiologistsScientists Issue Published: 1 November 1984 PDF DownloadLoading ...
Monitoring of EBV reactivation is justified in patients with aplastic anemia treated with rabbit ATG as a second course of immunosuppression
Authors: Marielle J. Wondergem, Servi J.C. Stevens, Jeroen J.W.M. Janssen, Joost J. Oudejans, Gert J. Ossenkoppele, Jaap M. Middeldorp, Sonja Zweegman
Journal: Blood (2008)
European parliament sets sights high for Cancun climate change talks
Authors: R. Watson
Journal: BMJ (2010)

The European Union is being urged to take the lead in the Cancun climate change negotiations opening on 29 November to regain the momentum after the setback at the previous international meeting in Copenhagen last December.

The message is being delivered by the European parliament’s environment committee in a detailed resolution covering all the items on the table that will be formally adopted by the full parliament on 25 November.

Jo Leinen, the German Christian Democrat who chairs the committee, acknowledges that a comprehensive worldwide treaty will not emerge from …
Regional myocardial blood flow reserve impairment and metabolic changes suggesting myocardial ischemia in patients with idiopathic dilated cardiomyopathy
Authors: Ad F.M van den Heuvel, Dirk J van Veldhuisen, Ernst E van der Wall, Paul K Blanksma, Hans-Marc J Siebelink, Willem M Vaalburg, Wiek H van Gilst, Harry J.G.M Crijns
Journal: Journal of the American College of Cardiology (2000)
Catalogue of medical ceramics
Authors: W. H. McMenemey
Journal: BMJ (1969)

JURNAL towards filing in aa omssion which was only too apparent to me...."The case histories are tantalizingly brief (was Billy really schizophrenic ?) and the criteria for clinical improvement are not always explicit.The non-Jungian reader may be forgiven for failing to be convinced that the therapist armed with this particular philosophy and approach does better than any other understanding and sympathetic adviser who can achieve effective rapport with the child and his family.
High-Grade Atrioventricular Blocks-Reply
Authors: Anil Bhandari
Journal: JAMA (1985)

<h3>In Reply.—</h3> We appreciate the comments of Dr Phibbs, which support the views we expressed in the editorial. Suspicion of high-grade AV block varies from patient to patient. We agree with Dr Phibbs that in an overwhelming majority of patients, the suspicion that high-grade AV block may be the cause of unexplained syncope usually arises if the patient has chronic bifascicular or trifascicular block. However, on rare occasions, an AV block can occur and cause syncope, even in patients with normal AV and intraventricular conduction times (Figure). The rhythm strip is of a 40-year-old cardiologist with a history of recurrent syncope. The patient did not have electrophysiological studies and it is not known whether such studies would have been useful. This patient's record emphasizes once again the major thrust of our editorial; namely, that we do not know all the answers and there is a need for clinical judgment in
637. Recombinant Adeno-Associated Viral Vector 2-Mediated Gene Transfer of VEGF165 Induces Neovascular Formation and Improves Blood Flow in Chronic Ischemic Swine Myocardium
Authors: Xiaoli Deng, Xiaobing Wu, Jie Jiang, Yanhong Guo, Lingyun Zu, Wei Gao
Journal: Molecular Therapy (2005)

Objective Vectors commonly used for therapeutic angiogenesis such as adenovirus and plasmid had their own limitations. Adenovirus-associated virus is a relatively new but probably more ideal vector as it is both safe and efficient. We will study the efficiency of rAAV2 mediated vascular endothelial growth factor165 gene transfer in inducing angiogenesis and arteriogenesis, in improving blood flow and myocardium function in a swine chronic myocardial ischemic model.
Effect of Store and Forward Teledermatology on Quality of Life
Authors: John D. Whited, Erin M. Warshaw, Karen E. Edison, Kush Kapur, Lizy Thottapurathu, Srihari Raju, Bethany Cook, Holly Engasser, Samantha Pullen, Patricia Parks, Tom Sindowski, Danuta Motyka, Rodney Brown, Thomas E. Moritz, Santanu K. Datta, Mary-Margaret Chren, Lucinda Marty, Domenic J. Reda
Journal: JAMA Dermatology (2013)

<h3>Importance</h3>Although research on quality of life and dermatologic conditions is well represented in the literature, information on teledermatology's effect on quality of life is virtually absent.<h3>Objective</h3>To determine the effect of store and forward teledermatology on quality of life.<h3>Design</h3>Two-site, parallel-group, superiority randomized controlled trial.<h3>Setting</h3>Dermatology clinics and affiliated sites of primary care at 2 US Department of Veterans Affairs medical facilities.<h3>Participants</h3>Patients being referred to a dermatology clinic were randomly assigned, stratified by site, to teledermatology or the conventional consultation process. Among the 392 patients who met the inclusion criteria and were randomized, 326 completed the allocated intervention and were included in the analysis.<h3>Interventions</h3>Store and forward teledermatology (digital images and a standardized history) or conventional text-based consultation processes were used to manage the dermatology consultations. Patients were followed up for 9 months.<h3>Main Outcome Measures</h3>The primary end point was change in Skindex-16 scores, a skin-specific quality-of-life instrument, between baseline and 9 months. A secondary end point was change in Skindex-16 scores between baseline and 3 months.<h3>Results</h3>Patients in both randomization groups demonstrated a clinically significant improvement in Skindex-16 scores between baseline and 9 months with no significant difference by randomization group (P = .66, composite score). No significant difference in Skindex-16 scores by randomization group between baseline and 3 months was found (P = .39, composite score).<h3>Conclusions</h3>Compared with the conventional consultation process, store and forward teledermatology did not result in a statistically significant difference in skin-related quality of life at 3 or 9 months after referral.<h3>Trial Registration</h3>clinicaltrials.gov Identifier: NCT00488293
Cardiac tamponade and central venous catheters.
Authors: M J Greenall, R W Blewitt, M J McMahon
Journal: BMJ (1975)

An analysis of the reports on 16 patients who developed cardiac tamponade, complicating the use of central venous catheters, showed that 14 died. The two survivors were treated by removal of the catheter and needle aspiration of the pericardial fluid. Some patients complained of warning symptoms such as nausea, pain, and dyspnoea, and the combination of tachycardia, hypotension, and raised venous pressure was common. We suggest that awareness of the hazard, radiographic visualization of the catheter tip, and expeditious treatment would reduce the mortality.
Images of Nurses: Perspectives From History, Art and Literature
Authors: Maggie Hadro-Venzke
Journal: JAMA (1988)

<i>Images of Nurses</i>is an excellent collection of works, which describe the historical, cultural, and sociological perceptions of nurses beyond the well-known secular imagery of Florence Nightingale. It is a series of essays that journey through time exploring ancient and modern artistic depictions of nurses, critiquing various literary creations of the mythical nurse/woman, and discussing the complex interrelationship between social issues such as racism and sexism and the image of professional nursing. This book is written by many nonnursing scholars who are prominent in the fields of art, literature, and humanities. These authors provide fascinating views on the continuing development and struggle of nursing to become a valued profession in our society. The book is divided into three sections. The first part deals with nursing imagery in the visual arts, the second with portrayals of nurses in literature, and the last with the stereotypes of nurses and women in relation
Magnetic Resonance Imaging With 3-Dimensional Analysis of Left Ventricular Remodeling in Isolated Mitral Regurgitation
Authors: Chun G. Schiros, Louis J. Dell'Italia, James D. Gladden, Donald Clark, Inmaculada Aban, Himanshu Gupta, Steven G. Lloyd, David C. McGiffin, Gilbert Perry, Thomas S. Denney, Mustafa I. Ahmed
Journal: Circulation (2012)

Background— Although surgery is indicated in patients with mitral regurgitation (MR) when left ventricular (LV) end-systolic (LVES) dimension is &gt;40 mm, LV ejection fraction may decrease after mitral valve surgery. We hypothesize that significant LV remodeling before surgery is not reflected by standard echocardiographic parameters measured at the base of the heart. Methods and Results— Ninety-four patients (age, 54±11 years; 38% female) with degenerative isolated MR underwent cine magnetic resonance imaging with tissue tagging and 3-dimensional analysis. In 51 control subjects (age, 44±14 years; 53% female), the relation between LVES volume (LVESV) and LVES dimension was quadratic, whereas in 94 MR patients, this relation was cubic, indicating a greater increase in LVESV per LVES dimension among MR patients. Moreover, magnetic resonance imaging LVESV from summated serial short-axis slices was significantly greater than LVESV assessed with the Bullet formula in MR patients, attributed to a more spherical remodeling distal to the tips of the papillary muscles ( P &lt;0.001). Thirty-five patients underwent mitral valve repair per current guideline recommendations. LV ejection fraction decreased from 61±7% to 54±8% ( P &lt;0.0001) and maximum shortening decreased significantly below normal at 1 year postoperatively ( P &lt;0.0001). Despite normalization of LV stroke volume and LV end-diastolic volume/mass ratio, there was a persistent significant increase in distal LVES 3-dimensional radius/wall thickness ratio and LVESV index after surgery. Conclusions— Despite apparently preserved LVES dimension, MR patients demonstrate significant spherical mid to apical LVES remodeling that contributes to higher LVESV than predicted by standard geometry-based calculations. Decreased LV strain after surgery suggests that a volumetric analysis of LV remodeling and function may be preferred to evaluate disease progression in isolated MR.
Using Moving Total Mortality Counts to Obtain Improved Estimates for the Effect of Air Pollution on Mortality
Authors: Steven Roberts
Journal: Environmental Health Perspectives (2005)

In many cities of the United States, measurements of ambient particulate matter air pollution (PM) are available only once every 6 days. Time-series studies conducted in these cities that investigate the relationship between mortality and PM are restricted to using a single day's PM as the measure of PM exposure. This is undesirable because current evidence suggests that the effects of PM on mortality are spread over multiple days. And studies have shown that using a single day's PM as the measure of PM exposure can result in estimates that have a large negative bias. In this article, I introduce a new model for estimating the mortality effects of PM when only every-sixth-day PM data are available. This new model uses information available in the daily mortality time series to infer otherwise lost information about the effect of PM on mortality over a period of more than a single day. This new model typically offers an increase in both statistical estimation precision and accuracy compared with existing models.
Carbohydrate Metabolism in Non-Insulin-Dependent Diabetes Mellitus
Authors: Sean Dinneen, John Gerich, Robert Rizza
Journal: New England Journal of Medicine (1992)

DIABETES mellitus is characterized by both fasting hyperglycemia and exaggerated postprandial increases in the plasma glucose level. Understanding the causes of these abnormalities is important for the rational use of current treatments and for developing more effective therapy. In this seminar, we review the physiology of normal carbohydrate metabolism and the pathophysiology of abnormalities in diabetes mellitus.Normal Physiology: Postabsorptive StateThe term "postabsorptive state" refers to the period 6 to 12 hours after a meal during which the transition from the postprandial to the fasting state occurs. At this time plasma glucose levels are at a nearly steady state; . . .
Erythema Nodosum and Indomethacin
Authors: FORTUNATO V. ELIZAGA
Journal: Annals of Internal Medicine (1982)

Letters and Corrections1 March 1982Erythema Nodosum and IndomethacinFORTUNATO V. ELIZAGA, M.D.FORTUNATO V. ELIZAGA, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-96-3-383_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: The letter by Barr and Robinson (1) describing a patient with chronic erythema nodosum who responded dramatically to indomethacin interested me as I have recently seen a similar case.A 57-year-old oriental man with acute myelogenous leukemia in complete remission, after receiving a single course of rubidazone, oncovin, adriamycin, and prednisone in February 1980, was found on exploratory laparotomy to have tuberculosis of the liver and spleen. He responded well to treatment with ethambutol, rifampin, and isoniazid. In September 1980 he developed painful, nodular, erythematous, tender lesions on his legs and arms. Beginning in November 1980 the...Reference1. BARRROBINSON WJ. Chronic erythema nodosum treated with indomethacin. Ann Intern Med. 1981;95:659. Letter. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: FORTUNATO V. ELIZAGA, M.D.Affiliations: 2228 Liliha Street #104, Honolulu, HI 96817 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byCutaneous Manifestations of Inflammatory Bowel Disease: A Basic OverviewMiscellaneous Systemic DrugsMedical Management of Extraintestinal Manifestations of Ulcerative ColitisMiscellaneous systemic drugsImportant cutaneous manifestations of inflammatory bowel diseaseCutaneous Manifestations of Inflammatory Bowel DiseaseErythema Nodosum in Children: A Study of 27 PatientsNonsteroidal Anti-inflammatory Drugs.Dermatologic therapy: December, 1981, through November, 1982 1 March 1982Volume 96, Issue 3Page: 383-383KeywordsAcute myeloid leukemiaErythemaIsoniazidLaparotomyLesionsLiverSpleen ePublished: 1 December 2008 Issue Published: 1 March 1982 PDF downloadLoading ...
A natriuretic factor in the serum of patients with chronic uremia
Authors: Jacques J. Bourgoignie, Kuo Hwa Hwang, Carlos Espinel, Saulo Klahr, Neal S. Bricker
Journal: Journal of Clinical Investigation (1972)

Sera from chronically uremic and normal individuals were subjected to gel filtration with Sephadex G-25 and the same fraction of both was infused into rats with a decreased nephron population to determine the effects on sodium excretion. Sodium excretion rate and fractional sodium excretion increased slightly with the normal fractions; but the increase in both functional parameters produced by the uremic fractions was substantially and significantly greater. The natriuresis could not be explained by associated changes in glomerular filtration rate (GFR), para-aminohippurate (PAH) clearance, filtration fraction, hematocrit, or blood pressure. The possibility thus exists that the inhibitor affected some component part of the transepithelial sodium transport system. The elution characteristics of the fraction plus certain of its physicochemical properties suggest that the inhibitor of sodium reabsorption by the rat nephron may be identical with the inhibitor of PAH uptake by kidney slices and the inhibitor of transepithelial sodium transport by the frog skin and toad bladder previously found in the serum of chronically uremic patients.
The place of botulinum toxin type A in the treatment of focal hyperhidrosis
Authors: N. LOWE, A. CAMPANATI, I. BODOKH, S. CLIFF, P. JAEN, O. KREYDEN, M. NAUMANN, A. OFFIDANI, J. VADOUD, H. HAMM
Journal: British Journal of Dermatology (2004)

Background Hyperhidrosis (primary or secondary) is excessive sweating beyond that required to return body temperature to normal. It can be localized or generalized, commonly affecting the axillae, palms, soles or face, and can have a substantial negative effect on a patient's quality of life. Impact of disease Objective evaluation comprising quantitative assessment (gravimetric and Minor's iodine starch test) and subjective evaluation (Dermatology Quality of Life Index and Hyperhidrosis Impact Questionnaire) allow accurate assessment of the impact of hyperhidrosis on patients. Botulinum toxin type A Botulinum toxin type A acts by inhibiting the release of acetylcholine at the presynaptic membrane of cholinergic neurones. It has proved useful in treating a number of diseases relating to muscular dystonia and is now proving beneficial in treating hyperhidrosis. Clinical trials investigating botulinum toxin type A use in axillary and palmar hyperhidrosis show significant benefits with few side-effects reported, with a favourable impact also being seen on patient quality of life. Botulinum toxin type A injections are generally well-tolerated with beneficial results lasting from 4 to 16 months. Conclusions Botulinum toxin type A injections are an effective and well-tolerated treatment for hyperhidrosis. This paper proposes a positioning of this treatment along with current established treatments, and highlights the role of botulinum toxin type A as a valuable therapy for the treatment of hyperhidrosis.