The Kidney in Cirrhosis
Authors: WILLIAM P. BALDUS
Journal: Annals of Internal Medicine (1964)

Article1 March 1964The Kidney in CirrhosisI. Clinical and Biochemical Features of Azotemia in Hepatic FailureWILLIAM P. BALDUS, M.D., RALPH N. FEICHTER, M.D., WILLIAM H. J. SUMMERSKILL, M.D.WILLIAM P. BALDUS, M.D.Search for more papers by this author, RALPH N. FEICHTER, M.D.Search for more papers by this author, WILLIAM H. J. SUMMERSKILL, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-60-3-353 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSimultaneous impairment of certain hepatic and renal functions may develop under widely different pathologic circumstances. Some authors have described such conditions by the term "hepatorenal syndrome," thus attributing a specific, but undefined, interrelationship to the liver and kidney (1-3). There are, however, strong indications that this syndrome represents a heterogenous group of disorders. It is therefore preferable to consider the various clinical and pathophysiologic changes individually. The following classification embraces the clinical circumstances in which common causes or direct relationships between renal and hepatic disorders have been most clearly substantiated:1. Systemic diseases involving both liver and kidney (infectious, toxic,...References1. HELWIGSCHUTZ FCCB: A liver kidney syndrome: clinical, pathological, and experimental studies. Surg. Gynec. Obstet. 55: 570, 1932. Google Scholar2. WILENSKY AO: Occurrence, distribution and pathogenesis of so-called liver death and/or the hepatorenal syndrome. Arch. Surg. (Chicago) 38: 625, 1939. CrossrefGoogle Scholar3. HEYD CG: A consideration of the hepaticorenal syndrome. Amer. J. Dig. Dis. 9: 348, 1942. CrossrefGoogle Scholar4. STAUFFER MH: Nephrogenic hepatosplenomegaly (abstract). Gastroenterology 40: 694, 1961. Google Scholar5. HECKERSHERLOCK RS: Electrolyte and circulatory changes in terminal liver failure. 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Author, Article, and Disclosure InformationAuthors: WILLIAM P. BALDUS, M.D.; RALPH N. FEICHTER, M.D.; WILLIAM H. J. SUMMERSKILL, M.D.Affiliations: From the Gastrointestinal Research Unit, Mayo Clinic and Mayo Foundation, Rochester, Minnesota.This investigation was supported in part by research grant AM-06908-01 from the National Institutes of Health, United States Public Health Service, Bethesda, Maryland.Dr. Baldus is a recipient of grant 2A-5259-C1 from the United States Public Health Service, Bethesda, Maryland.Read at the Forty-fourth Annual Meeting of the American College of Physicians, Denver, Colorado, April 1-5, 1963.Requests for reprints should be addressed to Section of Publications, Mayo Clinic, Rochester, Minnesota. 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WAKIM, M.D. 1 March 1964Volume 60, Issue 3Page: 353-365KeywordsAscitesCirrhosisKidneysLiverLiver diseasesMedical servicesPrevention, policy, and public healthRenal diseasesResearch grantsSystemic diseases ePublished: 1 December 2008 Issue Published: 1 March 1964 Copyright & PermissionsCopyright ©, 1964, by The American College of PhysiciansPDF downloadLoading ...