tbuckley/cabot-search huggingface dataset:
A Hospital on Wheels
Authors: Quentin L. Wood
Journal: JAMA (1968)

To the Editor:—  Being 20 miles from the nearest  is no cause for concern to the residents of the small community of Rancho Santa Fe, Calif.  Today the  comes to the patient—quickly, and fully prepared to cope. Medical men who have examined the Rancho's new hospital on wheels believe that numerous lives will be saved by this unique super-ambulance and its staff of men superbly trained by physicians determined to make the unit's personnel no less capable than the equipment itself.  The new Rancho Santa Fe mobile  treats the emergency patient on the spot. Ordinary ambulance services, modern and good as they may be, convey patients to a  for treatment and are manned accordingly. When the  is nearby, and service is reasonably prompt, such equipment and personnel are adequate.  But the residents of Rancho Santa Fe, typically retired yet active, are far more likely to
Confounding in epidemiological studies: why "independent" effects may not be all they seem.
Authors: G. D. Smith, A. N. Phillips
Journal: BMJ (1992)

passed a child health insurance bill, and we had to stop enrolling children because we ran out of money.It was only at the very last moment, at this last special legislative session, through extraordinary efforts by some really committed folks in the governor's office, that a deal was struck to expand the programme so we could reopen enrolment.The programme provides subsidised health insurance to children who do not qualify for Medicaid for primary ambulatory care-not hospital care, no medications, no high-tech procedures, just basic routine care, getting the infection treated before it turns into a major problem.It's a very narrow, circumscribed programme.But we need to expand it to all eligible children.The legislators chose children because frankly, from a political standpoint, children are easiest to sell.But as we discussed, there's so much need for expanded access to programmes like this, even before we get to comprehensive reform.It can be effective, I think, in targeting the most needy popu- lations and solving some of the biggest inequities in the system.So I think we can push ahead with things like insurance reform as we did in this legislative session- community rating, eliminating pre-existing conditions.We can push ahead with patchwork programmes like child health.Any amount of resources we can commit to that while we're trying to deal with the larger issues-how we're going to control costs in the major programmes and expand access and make sure that quality doesn't suffer at the same time.We have to do both.So I'd look forward to a lot of beneficial changes.I'd look forward to a more enlightened AIDS policy if we get a change of administration in Washington.I would hope even if we don't get a change of administration we would get a more enlightened AIDS policy, but I don't really see much prospect of that.
Stephen John Hadfield
Authors: E M Armstrong
Journal: BMJ (2007)

Stephen John Hadfield was born in Clapton, London, the son of a consultant anaesthetist. Following in his father's footsteps, he won a scholarship from Epsom College to Trinity College, Cambridge, and completed his medical studies at St Bartholomew's Hospital, London, winning the Bentley prize. Early work in surgery, anaesthetics, and midwifery was followed by a memorable trip to the United States as assistant surgeon aboard the Aquitania . 

In 1936 he married Jean MacDougall of MacDougall, younger daughter …
Clinical survey of 354 patients with gout.
Authors: R Grahame, J T Scott
Journal: Annals of the Rheumatic Diseases (1970)

Between the years 1958 and 1967, 354 patients with gout were examined personally at Hammersmith Hospital (257 cases seen between 1958 and 1967), and more recently at the Charing Cross and West London Hospitals (97 cases seen during 1966 and 1967).This paper describes a retrospective computer- assisted analysis of these patients.Some of them were followed for considerable periods of time by ourselves or our colleagues, whereas others were seen on one or two occasions only.The study does not therefore trace the course of the disorder over a period of time in individual patients. MethodFor the purpose of the survey gout was defined as recurrent acute episodes of arthritis in the presence of hyperuricaemia.Most of the serum urate values had been
Physician Supply Policies and Health Reform
Authors: Eli Ginzberg
Journal: JAMA (1992)

<h3>A LOOK BACKWARD</h3> IN A PERIOD like the present when the debate over health care reform becomes ever more insistent, recourse to history may provide some perspective, not so much to chart the way to the future but rather to deter the nation from advancing down unproductive paths. In the decade and a half following World War II there was mounting pressure from the public and the medical education establishment for congressional appropriations to expand the output of physicians on grounds that the existing medical school capacity was insufficient to meet the needs of a rapidly expanding population for access to health care services. By the early 1960s, key policy analysts of the American Medical Association (AMA) recognized that the Association's unremitting opposition to direct federal support for either the enhancement or the expansion of medical education could no longer be sustained. Its public relations efforts were now shifted to
Morbidity Following Acute Irritant Inhalation in a Population-Based Study
Authors: Paul D. Blanc
Journal: JAMA (1991)

<h3>Study Objective.—</h3> To estimate the incidence of and risk factors for morbidity due to inhalation of respiratory irritants. <h3>Design.—</h3> Six-month case series of inhalational exposures reported to a poison control center with follow-up, structured interviews of subjects. <h3>Setting.—</h3> A regional poison control center providing 24-hour telephone consultation to health professionals and the public. <h3>Patients.—</h3> Consecutive sample of 683 inhalation cases, with interviews of 323 subjects. <h3>Measurements and Main Results.—</h3> Moderate to severe irritants accounted for 160 (50%) of the inhalational exposures in interviewed subjects. Persistent symptoms lasting 14 days or longer were reported by only 20 (6%) of the subjects. Irritant exposure was a statistically significant risk factor for acute respiratory symptoms (relative risk [RR] = 1.7; 95% confidence interval [Cl], 1.4 to 2.1) but was unrelated to persistent symptoms. Preexisting lung conditions (RR = 2.4; 95% Cl, 1.4 to 4.2) and cigarette smoking (RR = 1.7; 95% CI, 1.3 to 2.2) were both statistically significant risk factors for persistent symptoms. <h3>Conclusions.—</h3> Symptomatic inhalational exposures due to irritants are frequent in reports from poison control centers. Residual morbidity was uncommon and did not appear to be statistically related to the degree of irritant exposure. Host-related factors may be better predictors of ongoing morbidity after inhalational exposure. (<i>JAMA</i>. 1991;266:664-669)
Galectin-1–expressing stromal cells constitute a specific niche for pre-BII cell development in mouse bone marrow
Authors: Frédéric Mourcin, Caroline Breton, Julie Tellier, Priyanka Narang, Lionel Chasson, Audrey Jorquera, Mark Coles, Claudine Schiff, Stéphane J. C. Mancini
Journal: Blood (2011)
Linking endothelial dysfunction with endothelial cell activation
Authors: James K. Liao
Journal: Journal of Clinical Investigation (2013)

The thin layer of cells that lines the interior of blood vessels, known as the endothelium, plays a complex role in vascular biology. The endothelium mediates blood vessel tone, hemostasis, neutrophil recruitment, hormone trafficking, and fluid filtration. Endothelial dysfunction, as defined by a lack of NO, has been linked to a variety of disease states, including atherosclerosis, diabetes mellitus, coronary artery disease, hypertension, and hypercholesterolemia. Indeed, restoration of endothelial function is one of the earliest recognizable benefits of statin therapy. In 1995, James Liao and colleagues published a study in the JCI demonstrating that NO is a vascular protective factor that limits endothelial activation and prevents leukocyte adhesion to the vessel wall.
Teaching article An introduction to the jargon of molecular biology Part II
Authors: B. Swynghedauw, J.-M. Moalic, F. Bourgeois, A. Barrieux
Journal: Cardiovascular Research (1993)

Journal Article Teaching article An introduction to the jargon of molecular biology Part II Get access Bernard Swynghedauw, Bernard Swynghedauw U127-INSERM, Hôpital Lariboisière, 41 Bd de la Chapelle, 75010 Paris, France: B Swynghedauw, J-M Moalic, F Bourgeois, A Barrieux. Correspondence to Dr Swynghedauw. Search for other works by this author on: Oxford Academic PubMed Google Scholar Jean-Marie Moalic, Jean-Marie Moalic U127-INSERM, Hôpital Lariboisière, 41 Bd de la Chapelle, 75010 Paris, France: B Swynghedauw, J-M Moalic, F Bourgeois, A Barrieux. Search for other works by this author on: Oxford Academic PubMed Google Scholar Francine Bourgeois, Francine Bourgeois U127-INSERM, Hôpital Lariboisière, 41 Bd de la Chapelle, 75010 Paris, France: B Swynghedauw, J-M Moalic, F Bourgeois, A Barrieux. Search for other works by this author on: Oxford Academic PubMed Google Scholar Alice Barrieux Alice Barrieux U127-INSERM, Hôpital Lariboisière, 41 Bd de la Chapelle, 75010 Paris, France: B Swynghedauw, J-M Moalic, F Bourgeois, A Barrieux. Search for other works by this author on: Oxford Academic PubMed Google Scholar Cardiovascular Research, Volume 27, Issue 9, September 1993, Pages 1566–1575, https://doi.org/10.1093/cvr/27.9.1566 Published: 01 September 1993
US may require insurance cover for bowel cancer screening
Authors: D. Josefson
Journal: BMJ (2002)

The US government is moving towards requiring that health insurers cover the cost of routine screening for bowel cancer, making the tests more widely available to the general public.

The move has provoked controversy in some quarters, on the grounds that mandatory screening for colon cancer amounts to “disease specific favouritism” and will drive up already high healthcare costs.

Colon cancer kills 56 600 Americans every year and is the second leading cause of death from cancer in the United States, …
Broken necks in passengers in London taxi accidents
Authors: C C Wray
Journal: BMJ (1986)

referenced with a colleague or senior member of the nursing staff.Further evidence of incom- petence must be presented to senior colleagues.The options open to them will be explained by the personnel officer of the district and may include secondment to a more supervised post for the remainder of this man's contract.It is most important for the registrar to realise that he is not alone in this dilemma.Many of us have faced it and I have had to persuade both doctors and paramedical staff to reconsider their career plans in the light of such findings of incompetence.
Schistosomiasis of the Cervix
Authors: A. H. Badawy
Journal: BMJ (1962)

Investigation of haemodynamic changes in schisto- somal cor pulmonale showed:(A) The presence of broncho-pulmonary arterial shunts proved by: (1) absence of correlation between the size of the pulmonary artery and its luminal pressure; (2) a progressive increase in the oxygen saturation in the pulmonary artery along its course;(3) the appearance in the pulmonary artery in 12 seconds of Evans blue dye injected into the aorta; (4) a sudden increase in the pressure as the catheter was drawn from the wedge to the pre-wedge position; and (5) on aorto- graphy by a special technique, the rapid filling of the big branches of the pulmonary artery through the bronchial arteries.(B) The presence of splenic shunts, as evidenced by: (1) a fall in the oxygen saturation in the inferior vena cava after splenectomy; and (2) a change towards normal in the size of the heart, in the electrocardiogram, and in the pulmonary arterial pressure after splenectomy.
A New Colonialism? — Conducting Clinical Trials in India
Authors: Samiran Nundy, Chandra M. Gulhati
Journal: New England Journal of Medicine (2005)

In January 2005, the government of India enacted a new rule that allows foreign pharmaceutical companies and other interested parties to conduct trials of new drugs in India at the same time that trials of the same phase are being conducted in other countries. This new rule supersedes a directive of India's Drugs and Cosmetics Rules that required a "phase lag" between India and the rest of the world. According to the old rule, if a phase 3 study had been completed elsewhere, only a phase 2 study was permitted in India. Even under the new rule, phase 1 trials . . .
Art about hospitals
Authors: A Padfield
Journal: Journal of the Royal Society of Medicine (2004)

The artists who have depicted events in hospital go back well before Lowry and Hepworth (mentioned in the letter of Nigel Cooke1). Visitors to the Royal Academy’s Vuillard Exhibition earlier this year may have seen The Surgeons, a large painting featuring the surgeon Dr Antonin Gossett and the anaesthetist Dr Bourreau.
Acute Respiratory Failure in Bronchiolitis and Pneumonia in Infancy. Modes of Presentation and Treatment
Authors: H. Simpson, D. J. Matthew, A. H. Habel, E. L. George
Journal: BMJ (1974)

The modes of presentation and the management of acute respiratory failure in 11 infants with severe lower respiratory tract infections (due to respiratory syncytial virus in eight) are described. Progressive respiratory difficulties leading to exhaustion, peripheral circulatory collapse, recurrent apnoeic attacks, or generalized convulsions were the main clinical presentations resulting in severe ventilatory failure. In nine infants preventilation carbon dioxide tensions exceeded 65 mm Hg. It seems likely that the use of intermittent positive-pressure ventilation in these patients contributed to the low mortality rate, less than 0.5%, from such illnesses during the 15-month study period.
Trend Analysis Of New Orleans Outdoor Mold Spore Counts: A Comparison Of Heal Preliminary Data And Post-katrina Mold Concentrations
Authors: L.F. Grimsley, W.E. Horner, L. White, H. Mitchell, S. Kennedy, J.M. El-Dahr, R. Cohn, Y. Sterling, M. Mvula, K. Stephens, M. Lichtveld, E. Thornton, P. Chulada, W. Martin
Journal: Journal of Allergy and Clinical Immunology (2010)
Daily Mail story on care of sick babies was "highly misleading," says BMJ editor
Authors: Z. Kmietowicz
Journal: BMJ (2012)

The BMJ ’s editor in chief, Fiona Godlee, has criticised the Daily Mail newspaper for misleading readers by publishing a highly inaccurate article on the care of severely disabled newborn babies that was based on a personal view article in the BMJ .

The Mail article appeared on its front page on 29 November with the banner “Now sick babies go on the death pathway: Doctor’s haunting testimony reveals how children are put on the end-of-life plan.”1

It claimed that the BMJ personal view, published anonymously on 1 November,2 was evidence that sick children in the NHS were being put on the Liverpool care pathway. It added, “The Mail can reveal the practice of withdrawing food and fluid by tube is being used on young patients as well as severely disabled newborn babies.”

However, in a letter to the Mail , which had not been published when the BMJ went to press, Godlee pointed out that “the doctor who wrote the BMJ article does not practise in the UK. Nor does the article mention the Liverpool care pathway” (box).

The Daily Telegraph ran a similar news item that was based on the Mail ’s story and that has been shared many hundreds of times on social media. However, that story has been deleted from the newspaper’s website after a BMJ reader pointed out its inaccuracies, although the Telegraph has refused to post a retraction.

Journalists at the Mail did not ask the BMJ for permission to …
Cost-effectiveness of HMG-CoA Reductase Inhibition for Primary and Secondary Prevention of Coronary Heart Disease
Authors: Lee Goldman
Journal: JAMA (1991)

To determine the cost-effectiveness of HMG-CoA (3-hydroxy-3-methylglutaryl coenzyme A) reductase inhibitors (such as lovastatin) for the primary and secondary prevention of coronary heart disease, we used the Coronary Heart Disease Policy Model, a computer-stimulated model that estimates the risk factor-specific annual incidence of coronary heart disease and the risk of recurrent coronary events in persons with prevalent coronary heart disease. When used for secondary prevention, 20 mg/d of lovastatin was estimated to save lives and save costs in younger men with cholesterol levels above 250 mg/dL (6.47 mmol/L) and to have a favorable cost-effectiveness ratio regardless of the cholesterol level except in young women with cholesterol levels below 250 mg/dL (6.47 mmol/L). Doses of 40 mg/d of lovastatin had favorable incremental cost-effectiveness ratios in men with cholesterol levels above 250 mg/dL (6.47 mmol/L). By comparison, primary prevention had favorable cost-effectiveness ratios only in selected subgroups based on cholesterol levels and other established risk factors. We conclude that current national recommendations regarding medication for secondary prevention are not as aggressive as our projections would suggest, while recommendations regarding the use of medications for primary prevention should consider the cost of medication as well as the risk factor profile of the individual patient.
Transnavicular Perilunar Carpal Dislocation
Authors: Otto E. Aufranc
Journal: JAMA (1966)

Dr. Turner: An 18-year-old girl fell while playing football. She attempted to break the fall with her outstretched right hand and experienced severe pain in the right wrist. She was seen at the Massachusetts General Hospital one hour following injury. Results of a physical examination were completely normal except for the right wrist. There was pain, swelling, and deformity of the wrist with dorsal displacement of the hand and distal carpal bones in relation to the distal radius. Circulation and sensation were completely intact. X-ray films showed a transverse fracture through the mid portion of the navicular, with dorsal dislocation of the distal navicular fragment and the entire distal carpal row. The lunate remained in its normal relationship with the distal radius. (Fig 1). Dr. Aufranc: Dr. Edward A. Nalebuff, of our Massachusetts General Hospital staff, has been very interested in hand and wrist injuries, and will discuss the mechanism
Training General Internists and “STARS”
Authors: Charles Moser
Journal: Annals of Internal Medicine (1995)

Letters1 January 1995Training General Internists and “STARS”Charles Moser, MD, PhDCharles Moser, MD, PhDSt. Mary's Medical Center; San Francisco, CA 94117Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-122-1-199501010-00029 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Fogelman's strategy [1] to make general internal medicine more appealing to young physicians is interesting and innovative. Unfortunately, he repeats the unsubstantiated claim that there is a shortage of primary care physicians in the United States. This claim is behind many proposed changes in the medical education system and deserves closer scrutiny.Using a strict definition of primary care physicians (including only general internists, general pediatricians, family physicians, and general practitioners in office-based practice), there are 51 primary care physicians per 100 000 persons [2]. This excludes all the interns, residents, and teaching staff who provide much of ...References1. Fogelman AM. Strategies for training generalists and subspecialists. Ann Intern Med. 1994; 120:579-83. Google Scholar2. American Medical Association. Physician characteristics and distribution in the United States; 1992. Google Scholar3. Kronick R, Goodman DC, Wennberg J, Wagner E. The marketplace in health care reform. The demographic limitations of managed competition. N Engl J Med. 1993; 328:148-52. Google Scholar4. Mulhausen R, McGee J. Physician need—An alternative projection from a study of large, prepaid group practices. JAMA. 1989;261:1930-4. Google Scholar5. Steinwachs DM, Weiner JP, Shapiro S, Batalden P, Coltin K, Wasserman F. A comparison of the requirements for primary care physicians in HMOs with projections made by the GMENAC. N Engl J Med. 1986; 314:217-22. Google Scholar Author, Article, and Disclosure InformationAffiliations: St. Mary's Medical Center; San Francisco, CA 94117 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 January 1995Volume 122, Issue 1Page: 72-73KeywordsMedical educationNursesPrimary care physicians ePublished: 15 August 2000 Issue Published: 1 January 1995 Copyright & PermissionsCopyright © 1995 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Interarterial Coronary Anastomoses and Coronary Arterial Pattern
Authors: W. J. PEPLER, B. J. MEYER
Journal: Circulation (1960)

The coronary arterial pattern and coronary anastomoses have been investigated in 90 European and 98 Bantu hearts. A significantly better coronary anastomotic blood supply has been demonstrated in Bantu hearts. This was found to be present from a very early age onward and not related to hypertrophy, atherosclerosis of the coronary arteries, or to gross anatomic differences of the arterial tree, such as a third primary division of the left coronary artery. The latter was found to be more common (74 per cent) in Bantu than in European hearts (38 per cent). It is suggested that the reason for the better anastomoses might be the high incidence of megaloblastic and iron-deficiency anemia in Bantu children. The low incidence of the severe degrees of coronary atherosclerosis and its complications has been reaffirmed in the Bantu hearts.
Making a mark
Authors: A. Hodges
Journal: BMJ (1999)

23 year old Martin Bryant entered a tourist complex 100 km south of Hobart, Tasmania, and shot dead 35 people, wounding 18 others.The media described it as "the worst massacre by a single gunman in Australian history," although Chapman points out on page 1 that the wholesale slaughter of aborigines in the 19th century often involved far higher individual tallies. Beforethis watershed tragedy, Australia's eight states and territories had different laws.In practice, they operated on or below the lowest denominator (ironically, that of Tasmania).For years, attempts to limit gun ownership had floundered in political backwaters, fobbed off by politicians cowed by vocal pro-gun lobbyists.After the massacre, obfuscation was cut through and a practical national gun agreement put in place.This included a ban on semiautomatic and pump action rifles, a compensatory buy back scheme, a register of all firearms, shooter licensing based on a "genuine reason for owning a firearm," safe storage requirements, and uniform national laws.Myths surrounding gun control abound."Guns don't kill people, people do" has had a successful run in the United States, but the Australian public simply did not buy this argument.I cheered when the epidemiological arsenal of sensitivity, specificity, and power was used to knock the stuffing out of arguments for a prohibited persons register; to prevent 570 assaults yet miss 30 each year in New Zealand alone would entail locking up 150 000 Kiwis.
Diabetics and motorway crashes.
Authors: G E Leyshon, R W Elliott, J Lyons, H W Francis
Journal: BMJ (1972)

glands are cholinergic and show muscarinic characteristics.They are therefore blocked by muscarinic antagonists such as atropine but are quite unaffected by alpha blockers.The second point arises from the state- ment that noradrenaline is without direct effect on the myocardium.Although the spectrum of agonist activity of noradren- aline is predominantly alpha it does exhibit some beta activity, and therefore it is false to imagine the myocardium immune from the actions of noradrenaline.-Iam, etc.,