Neoplastic Plasma Cell
Authors: NATHANIEL I. BERLIN
Journal: Annals of Internal Medicine (1963)

Clinical Staff Conference1 June 1963Neoplastic Plasma CellCombined Clinical Staff Conference at the National Institutes of HealthNATHANIEL I. BERLIN, M.D., RUTH MERWIN, PH.D., MICHAEL POTTER, M.D., JOHN L. FAHEY, M.D., PAUL P. CARBONE, M.D., MARTIN J. CLINE, M.D.NATHANIEL I. BERLIN, M.D.Search for more papers by this author, RUTH MERWIN, PH.D.Search for more papers by this author, MICHAEL POTTER, M.D.Search for more papers by this author, JOHN L. FAHEY, M.D.Search for more papers by this author, PAUL P. CARBONE, M.D.Search for more papers by this author, MARTIN J. CLINE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-58-6-1017 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptDr. Nathaniel I. Berlin: Multiple myeloma is a disease of the plasma cells, characterized by lytic lesions in the bone and by the production of abnormal proteins, for which there is no satisfactory therapy. New approaches utilizing advances in protein chemistry, immunology, and biology have made possible a number of studies of the malignant plasma cell in man and in mice. Plasma-cell tumors have been produced in mice—experimental animal tumors that are comparable to multiple myeloma in man.In preparing this program I have selected from a larger number of studies in the National Cancer Institute those which illustrate selected...References1. RASK-NIELSENGORMSEN RH: Spontaneous and induced plasma-cell neoplasia in a strain of mice. Cancer 4: 387, 1951. CrossrefMedlineGoogle Scholar2. MERWINALGIRE RMGH: Induction of plasma-cell neoplasms and fibrosarcomas in BALB/c mice carrying diffusion chambers. Proc. Soc. Exp. Biol. Med. 101: 437, 1959. CrossrefMedlineGoogle Scholar3. 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Author, Article, and Disclosure InformationAffiliations: Bethesda, MarylandThis is an edited transcription of a combined clinical staff conference at the Clinical Center, Bethesda, Maryland, by the National Cancer Institute, National Institutes of Health, United States Public Health Service, Department of Health, Education, and Welfare.Requests for reprints should be addressed to Nathaniel I. Berlin, M.D., National Cancer Institute, Bethesda 14, Maryland. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byRheumafaktoren bei ParaproteinämienEvaluation of chemical agents against the plasma cell tumor LPC-1 in miceMechanism of Adrenal-Steroid Reversal of Hypercalcemia in Multiple Myeloma 1 June 1963Volume 58, Issue 6Page: 1017-1036KeywordsAnemiaImmunologyLesionsMedical servicesMultiple myelomaOsteocalcinPlasma cellsPlasma proteinsPrevention, policy, and public healthProteins Issue Published: 1 June 1963 PDF downloadLoading ...