The Quest for a Cholesterol-decreasing Diet: Should We Subtract, Substitute, or Supplement?
Authors: Thomas A. Pearson
Journal: Annals of Internal Medicine (1993)

Editorials1 October 1993The Quest for a Cholesterol-decreasing Diet: Should We Subtract, Substitute, or Supplement?Thomas A. Pearson, MD, PhD and Rajesh V. Patel, BAThomas A. Pearson, MD, PhDColumbia University, New York, New York.Search for more papers by this author and Rajesh V. Patel, BAColumbia University, New York, New York.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-119-7_Part_1-199310010-00013 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Recent reports from the National Cholesterol Education Program have documented the continued decrease of serum cholesterol levels in U.S. adults. Using data from the National Health and Nutrition Examination Surveys, the mean cholesterol level for adults, ages 20 to 74 years, was shown to have decreased from 5.69 mmol/L (220 mg/dL) in 1960 to 1962 to 5.30 mmol/L (205 mg/dL) in 1988 to 1991 [1]. This decrease was observed in essentially all race and sex subgroups and was most marked in the past 10 years. Although cholesterol-decreasing drugs have increased in use, it is likely that most of this decrease ...References1. Johnson CL, Rifkind BM, Sempos CT, Carroll MD, Bachorik PS, Briefel RR, et al. Declining serum total cholesterol levels among US adults. The National Health and Nutrition Examination Surveys. JAMA. 1993; 269:3003-8. Google Scholar2. Sempos CT, Cleeman JI, Carroll MD, Johnson CL, Bachorik PS, Gordon DJ, et al. Prevalence of high blood cholesterol among US adults. An update based on guidelines from the second report of the National Cholesterol Education Program Adult Treatment Panel. JAMA. 1993; 269:3009-14. Google Scholar3. Davis PA, Platon J-F, Gershwin ME, Halpern GM, Keen CL, DiPaulo D, et al. A linoleate-enriched cheese product reduces low density lipoprotein in moderately hypercholesterolemic adults. Ann Intern Med. 1993; 119:555-9. Google Scholar4. Sprecher DL, Harris BV, Goldberg AC, Anderson PA, Bayuk LM, Russell BS, et al. Efficacy of psyllium on reducing serum cholesterol in hypercholesterolemic patients on high or low fat diets. Ann Intern Med. 1993; 119:545-54. Google Scholar5. Warshafsky S, Kamer RS, Sivak SL. Effect of garlic on total serum cholesterol: A meta-analysis. Ann Intern Med. 1993; 119:599-605. Google Scholar6. Carleton RA, Dwyer J, Finberg L, Flora J, Goodman DS, Grundy SM, et al. Report of the Expert Panel on Population Strategies for Blood Cholesterol Reduction. A Statement from the National Cholesterol Education Program, National Heart, Lung, and Blood Institute, National Institutes of Health. Circulation. 1991; 83:2154-232. Google Scholar7. Summary of the second report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II). JAMA. 1993; 269:3015-23. Google Scholar8. Stephen AM, Wald NJ. Transient individual consumption of dietary fat in the United States, 1920-1984. Am J Clin Nutr. 1990; 52:457-69. Google Scholar9. Krebs-Smith SM, Cronin FJ, Haytowitz DB, Cook DA. Food sources of energy, macronutrients, cholesterol, and fiber in diets of women. J Am Diet Assoc. 1992; 168-74. Google Scholar10. Mensink RP, Katan MB. The effect of a diet enriched with monounsaturated or polyunsaturated fatty acids on levels of low-density and high-density lipoprotein cholesterol in healthy men and women. N Engl J Med. 1989; 321:436-41. Google Scholar Author, Article, and Disclosure InformationAffiliations: Columbia University, New York, New York.Corresponding Author: Thomas A. Pearson, MD, PhD, M.I. Bassett Research Institute, One Atwell Road, Cooperstown, NY 13326. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoEfficacy of Psyllium in Reducing Serum Cholesterol Levels in Hypercholesterolemic Patients on High- or Low-Fat Diets Dennis L. Sprecher , Betsy V. Harris , Anne C. Goldberg , E. Carl Anderson , Linda M. Bayuk , Betsy S. Russell , Debbie S. Crone , Catherine Quinn , Joyce Bateman , Barbara R. Kuzmak , and Lisa D. Allgood A Linoleate-enriched Cheese Product Reduces Low-Density Lipoprotein in Moderately Hypercholesterolemic Adults Paul A. Davis , Jean-Francois Platon , M. Eric Gershwin , Georges M. Halpern , Carl L. Keen , Donna DiPaolo , Janet Alexander , and Vincent A. Ziboh Effect of Garlic on Total Serum Cholesterol Stephen Warshafsky , Russell S. Kamer , and Steven L. Sivak A Linoleate-enriched Cheese Product Reduces Low-Density Lipoprotein in Moderately Hypercholesterolemic Adults Paul A. Davis , Jean-Francois Platon , M. Eric Gershwin , Georges M. Halpern , Carl L. Keen , Donna DiPaolo , Janet Alexander , and Vincent A. Ziboh Effect of Garlic on Total Serum Cholesterol Stephen Warshafsky , Russell S. Kamer , and Steven L. Sivak Efficacy of Psyllium in Reducing Serum Cholesterol Levels in Hypercholesterolemic Patients on High- or Low-Fat Diets Dennis L. Sprecher , Betsy V. Harris , Anne C. Goldberg , E. Carl Anderson , Linda M. Bayuk , Betsy S. Russell , Debbie S. Crone , Catherine Quinn , Joyce Bateman , Barbara R. Kuzmak , and Lisa D. Allgood Metrics Cited ByChronic myeloid disorders, excluding CMLPerspectives: How many women have osteoporosis now? 1 October 1993Volume 119, Issue 7_Part_1Page: 627-628KeywordsCheesesCholesterolDietDrug interactionsDrugsFatsFoodHealth surveysLow density lipoproteinNutrition Issue Published: 1 October 1993 CopyrightCopyright © 1993 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...