After 20 Years, Liver Transplantation Comes of Age
Authors: DAVID H. VAN THIEL
Journal: Annals of Internal Medicine (1983)

Editorials1 December 1983After 20 Years, Liver Transplantation Comes of AgeDAVID H. VAN THIEL, M.D., ROBERT R. SCHADE, M.D., THOMAS E. STARZL, M.D., PH.D.DAVID H. VAN THIEL, M.D.Search for more papers by this author, ROBERT R. SCHADE, M.D.Search for more papers by this author, THOMAS E. STARZL, M.D., PH.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-99-6-854 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAfter 20 years as an experimental procedure, orthotopic liver transplantation for patients with advanced hepatic disease has come of age (1, 2). Survival statistics from the four centers with the most experience suggest that the 1-year survival for children having a hepatic transplant should exceed 70%, whereas that for adults should exceed 50% and may, with more care given to the choice of candidates and experience, approach the level of success being achieved in children (3-7). Late deaths among transplant recipients occurring after the first year of survival are unusual and attrition after 1 year of survival actually approaches that...References1. STARZLMARCHIOROVONKAULLA TTK. Homotransplantation of the liver in humans. Surg Gynecol Obstet. 1963;117:659-79. MedlineGoogle Scholar2. STARZLIWATSUKIVAN THIEL TSD. Evolution of liver transplantation. Hepatology. 1982;2:614-36. CrossrefMedlineGoogle Scholar3. STARZLIWATSUKISHAW TSB. Consensus conference report on liver transplantation. Hepatology. 1984 (In press). Google Scholar4. ROLLESCALNE KR. Orthotopic liver transplantation 1968-1983: the Cambridge experience. Hepatology. 1984 (In press). CrossrefMedlineGoogle Scholar5. PICHLMAYR R. Consensus development conference on liver transplantation: experience with liver transplantation. Hepatology. 1984 (In press). CrossrefMedlineGoogle Scholar6. KROMGIPSHOUTHOFF RCJ. Orthotopic liver transplantation in Groningen (The Netherlands) 1979-1983. Hepatology. 1984 (In press). Google Scholar7. SCHARSCHMIDT B. Experience with liver transplantation. Hepatology. 1984 (In press). MedlineGoogle Scholar8. BORELFEURERGUBLERSTAHELIN JCHH. Biological effects of cyclosporin A: a new antilymphocytic agent. Agents Actions. 1976;6:468-75. CrossrefMedlineGoogle Scholar9. BORELFEURERMAGNCESTAHELIN JCCH. Effects of the new antilymphocytic peptide cyclosporin A in animals. Immunology. 1977;32:1017-25. MedlineGoogle Scholar10. KOSTAKISWHITECALNE ADR. Prolongation of rat heart allograft survival by cyclosporin A. IRCS Med Sci. 1977;5:280. Google Scholar11. GREENALLISON CA. Extensive prolongation of rabbit kidney allograft survival after short term cyclosporin A treatment. Lancet. 1978;1:1182-3. CrossrefMedlineGoogle Scholar12. CALNEWHITETHIRU RDS. Cyclosporin A in patients receiving renal allografts from cadaver donors. Lancet. 1978;2:1323-7. CrossrefMedlineGoogle Scholar13. CALNEROLLESWHITE RKD. Cyclosporin A initially as the only immunosuppressant in 34 patients of cadaveric organs: 32 kidneys, 2 pancreases and 2 livers. Lancet. 1979;2:1033-6. CrossrefMedlineGoogle Scholar14. VAN THIELSCHADESTARZLIWATSUKISHAWGAVALERDUGAS DRTSBJM. Liver transplantation in adults. Hepatology. 1982;2:637-40. CrossrefMedlineGoogle Scholar15. VAN THIELSCHADEGAVALERSHAWIWATSUKISTARZL DRJBST. Medical aspects of liver transplantation. Hepatology. 1984. (In press). CrossrefGoogle Scholar16. . Submitted to the Commissioner of Public Health, May, 1983. Available from Joan M. Gorga, Special Assistant for Policy and Planning, Department for Public Health, 600 Washington Street, Boston, MA 02111 Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: DAVID H. VAN THIEL, M.D.; ROBERT R. SCHADE, M.D.; THOMAS E. STARZL, M.D., PH.D.Affiliations: University of Pittsburgh School of Medicine Pittsburgh, Pennsylvania PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byLiver transplantation: What do we really know about the long-term impact?Effect of end-stage liver failure on the incidence and resolution of the adult respiratory distress syndromeLiver Transplantation in Europe—Present StatusThe regulation of organ procurement and transplantation in the United StatesRadiographic features of liver allograft rejectionExigent ileostomy hemorrhageSurgery runs amokEthical and Policy Issues in the Procurement of Cadaver Organs for Transplantation 1 December 1983Volume 99, Issue 6Page: 854-856KeywordsChildrenLiver diseasesLiver transplantationOrthotopic liver transplantation ePublished: 1 December 2008 Issue Published: 1 December 1983 PDF downloadLoading ...