The Coronary Collateral Circulation
Authors: Richard H. Helfant, Richard Gorlin
Journal: Annals of Internal Medicine (1972)

Editorials1 December 1972The Coronary Collateral CirculationRICHARD H. HELFANT, M.D., F.A.C.P., RICHARD GORLIN, M.D., F.A.C.P.RICHARD H. HELFANT, M.D., F.A.C.P., RICHARD GORLIN, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-77-6-995 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe widespread use of coronary arteriography and revascularization surgery has stimulated interest in the coronary collateral circulation. It is now generally accepted that collaterals are congenitally determined channels; however, after more than 3 decades of study, the factors that stimulate their function and the degree to which collaterals protect patients with coronary artery disease remain controversial. It is pertinent and timely to examine the current knowledge of collateral formation and function.FACTORS THAT PROMOTE CORONARY COLLATERAL FUNCTIONPhysical Activity:With progressive increases in physical fitness, the patient with angina pectoris develops a progressive increase in exercise tolerance, and a given...References1. ECKSTEIN R: Effect of exercise and coronary artery narrowing on coronary collateral circulation. Circ Res 5:230-235, 1957 CrossrefMedlineGoogle Scholar2. KAPLINSKYHOODMCCARTHY EWB: Effects of physical training in dogs with coronary artery ligation. Circulation 37:556-565, 1968 CrossrefMedlineGoogle Scholar3. BJORK L: Angiographic demonstration of collaterals to the coronary arteries in patients with angina pectoris. Acta Radiol [Diagn] (Stockh) 8:305-309, 1969 MedlineGoogle Scholar4. HELFANTVOKONASGORLIN RPR: Functional importance of the human coronary collateral circulation. N Engl J Med 284:1277-1281, 1971 CrossrefMedlineGoogle Scholar5. 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