Sister Mary Joseph's Nodule
Authors: Vicente Giner Galvan
Journal: Annals of Internal Medicine (1998)

Letters1 March 1998Sister Mary Joseph's NoduleVicente Giner Galvan, MDVicente Giner Galvan, MDHospital Clinic i Provincial; Barcelona, SpainAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-128-5-199803010-00017 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Sister Mary Joseph's nodule has traditionally been considered a sign of ominous prognosis (survival of 10 months on average) and suggests therapeutic abstention [1]. We conducted a MEDLINE search of papers published from 1966 to January 1997 to evaluate the evidence for this belief.It seems necessary to obtain a histopathologic diagnosis because most umbilical tumors are primary [2]. Fine-needle aspiration biopsy has been established as an adequate method for early and easy diagnosis [3]. A total of 407 reports of Sister Mary Joseph's nodules have been published. The most common origins are gastrointestinal (52%), gynecologic (28%), ...References1. Clements AB. Metastatic carcinoma of umbilicus. JAMA. 1952; 150:556-9. Google Scholar2. Barrow MV. Metastatic tumors of the umbilicus. J Chronic Dis. 1966; 19:1113-7. Google Scholar3. Schneider V, Smyczek B. Sister Mary Joseph's nodule. Diagnosis of umbilical metastases by fine needle aspiration. Acta Cytol. 1990; 34:555-8. Google Scholar4. Majmudar B, Wiskind AK, Croft BN, Dudley AG. The Sister (Mary) Joseph nodule: its significance in gynecology. Gynecol Oncol. 1991; 40:152-9. Google Scholar5. Srinivasan R. Metastatic cutaneous and subcutaneous deposits from internal carcinoma. An analysis of cases diagnosed by fine needle aspiration. Acta Cytol. 1993; 37:894-8. Google Scholar Author, Article, and Disclosure InformationAffiliations: Hospital Clinic i Provincial; Barcelona, Spain PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited BySister Mary Joseph's Nodule from Pancreatic CancerPancreatic cancer in 2021: What you need to know to winAsymptomatic periumbilical nodule: a sinister signAggressive anaplastic ovarian carcinoma in a young nulliparous patientCancer of Exocrine PancreasUmbilical Metastasis Secondary to Ovarian Carcinoma - A Rare Case of Sister Mary Joseph NoduleCalcified Sister Mary Joseph nodule as the presenting complaint of advanced low-grade serous ovarian cancerThe Genital, Perianal, and Umbilical RegionsSister Mary Joseph Nodule as an Initial Presentation of Pancreatic AdenocarcinomaCutaneous Metastases in Ovarian CancerCutaneous Metastasis after Surgery, Injury, Lymphadenopathy, and Peritonitis: Possible MechanismsEl signo de la hermana María José, un hallazgo semiológico que no se debe olvidar. Reporte de un caso (con video)Cutaneous MetastasisThe Sister Mary Joseph noduleInspection of the AbdomenNódulo de la hermana María José y linfoma difuso de células grandes BUmbilical metastasis mimicking symptomatic hernia: Report of a case of Sister Mary Joseph SyndromeSister Mary Joseph nodule caused by metastatic desmoplastic small round cell tumor: A clinicopathological reportUnusual Cause of an Umbilical NodulePrimary peritoneal carcinoma presenting as a Sister Mary Joseph's nodule: A case report and review of the literatureA bleeding umbilical massSister Mary Joseph noduleCholangicarcinoma Presenting as a Sister Mary Joseph NoduleNon-umbilical Cutaneous Metastasis of Pancreatic Adenocarcinoma as the First Clinical Manifestation: A Case ReportUmbilical metastasis derived from breast cancer: report of a caseHuge uterine leiomyoma combined with umbilical inclusion cyst mimicking a Sister Mary Joseph's noduleUmbilical metastasis derived from early stage rectal cancer: a case reportCholangiocarcinoma Presenting as Sister Mary Joseph's Nodule: Case Report and Short Review of the LiteratureLate Dermatologic ConditionsSister Mary Joseph's Nodule Presenting as Large Bowel Obstruction: A Case Report and Brief Review of the LiteratureSister Mary Joseph Nodule in Endometrial CarcinomaA case of Sister Mary Joseph^|^rsquo;s nodule from recurrent ovarian cancerSister Mary Joseph's nodule associated with rare endometrial squamous cell carcinomaSister Mary Joseph NoduleInspection of the AbdomenAn Infrequent Case of Neoplasm With Fibroepithelioma of Pinkus and Hidradenomatous Features Arising at the Umbilicus: A Rare FindingUmbilical Metastasis (Sister Mary Joseph's Nodule) From Esophageal Squamous Cell CarcinomaA Man With a Testicular Mass and a Colon StenosisSister Mary Joseph's nodule derived from pancreatic cancerUmbilical MassSister Mary Joseph nodule as a first manifestation of ovarian carcinomaUitgevers krijgen het moeilijkNavelstaren met Sister Mary JosephUmbilical Metastasis From Breast Cancer Detected by FDG PETSister Mary Joseph and Her Nodule: Historical and Clinical PerspectiveUn cas rare de métastase ombilicale de tumeur viscérale. Éponyme: nodule de Sœur-Marie-JosephMetastatic neuroendocrine malignancy presenting as Sister Mary Joseph's noduleForgotten node: A case reportSister Mary Joseph's nodule: Three case reportsFine-needle aspiration cytology of Sister Mary Joseph's (paraumbilical) nodulesUmbilical Metastasis or Sister Mary Joseph's Nodule as a very Early Sign of an Occult Cecal AdenocarcinomaSister Mary Joseph's Nodule as the Sole Presenting Feature of Disseminated Squamous Cell Cancer of the Esophagus: A Rare CaseSignet Cell Gastric Adenocarcinoma Presenting as a Sister Joseph NoduleSister Mary Joseph's nodule as a metastasis of gallbladder carcinomaVillar's nodule: A case report and systematic literature review of endometriosis externa of the umbilicusPancreatic Cancer Presenting as a Sister Mary Joseph's NoduleSister Mary Joseph's nodule originating from endometrial carcinoma incidentally detected during surgery for an umbilical hernia: a case reportLaparoscopic scar: A mimicker of Sister Mary Joseph's nodule on positron emission tomography/CTSister Mary Joseph nodule: an important sign of an ominous diagnosisSister Mary Joseph's nodule as the first presenting sign of primary fallopian tube adenocarcinomaFine needle aspiration biopsy of gastrointestinal stromal tumor presenting as an umbilical mass (Sister Mary Joseph's Nodule)Umbilical metastasis from breast cancer related with tumor marker elevationMR imaging features of endometriosis at the umbilicusNódulo de la Hermana María (José) como forma de presentación de un linfoma no hodgkinianoMetastatic Tumors of the Umbilicus: Report of Two Cases and Review of the LiteratureCarcinoma of the gallbladder with unusual umbilical metastasisWho was Sister Mary Joseph?Fine-needle aspiration cytology of umbilical nodules: ?Sister Joseph's nodule?Penser à regarder son nombril…Pseudo Sister Mary Joseph's Nodule 1 March 1998Volume 128, Issue 5Page: 410KeywordsAdenocarcinomaBenign tumorsBiopsyOvarian cancerStomach Issue Published: 1 March 1998 CopyrightCopyright © 1998 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...