Calcified Granulomata of the Spleen in Long Standing Brucellar Infection
Authors: ELLARD M. YOW
Journal: Annals of Internal Medicine (1961)

Case Reports1 August 1961Calcified Granulomata of the Spleen in Long Standing Brucellar InfectionA Report of a Case of Twenty-five Years' DurationELLARD M. YOW, M.D., F.A.C.P., JAMES C. BRENNAN, M.B., B.CH., M. H. NATHAN, M.D., LOUIS ISRAEL, M.S.ELLARD M. YOW, M.D., F.A.C.P.Search for more papers by this author, JAMES C. BRENNAN, M.B., B.CH.Search for more papers by this author, M. H. NATHAN, M.D.Search for more papers by this author, LOUIS ISRAEL, M.S.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-55-2-307 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe symptoms of brucellosis in human beings usually disappear within a year whether or not the patient is treated. Occasionally the brucellae may remain viable in reticuloendothelial cells or in granulomata for long periods without producing clinical symptoms. In a few patients, the infection may be sufficiently active either chronically or intermittently to produce local and systemic evidence of infection (1, 2).The persistence of organisms in foci within the central nervous system, bones and joints, liver, heart, kidney, prostate, and eye has been reported or reviewed by Spink (1). Other reports reveal 11 patients in whom there were definite...References1. SPINK WW: The Nature of Brucellosis, The University of Minnesota Press, Minneapolis, 1956. Google Scholar2. BRAUDE AI: Brucellosis. Disease-a-Month, Dec. 1957. CrossrefMedlineGoogle Scholar3. SPINK WW: Suppuration and calcification of the liver and spleen due to long-standing infection with Brucella suis. New Engl. J. Med. 257: 209, 1957. CrossrefMedlineGoogle Scholar4. SPINKHALLAAGARD WWWHGN: Chronic brucellosis. Bull. Staff Mtg. Univ. Minn. Hosp. 17: 194, 1956. Google Scholar5. OSMUNDSONMARTINMERRITTSTROEBEL PJWJWACF: Brucellosis: report of an unusual case. Proc. Mayo Clin. 32: 58, 1957. MedlineGoogle Scholar6. Case Records of the Massachusetts General Hospital (Case No. 42461). New Engl. J. Med. 255: 958, 1956. CrossrefMedlineGoogle Scholar7. SCHIRGERDEARINGWAUGH AWHJM: Intermittent fever over a 17-year period in a patient with hypersplenism due to brucellosis. Proc. Mayo Clin. 34: 262, 1959. MedlineGoogle Scholar8. WAINWRIGHT CA: Malta fever in the United States. Bull. Johns Hopkins Hosp. 45: 133, 1929. Google Scholar9. AMOSS HC: Localization of brucella. International Clinics, 41st series 4: 93, 1931. Google Scholar10. FORBESLOWRYGIBSONSOANES KAECTEWA: Brucellosis of the genitourinary tract: review of the literature and report of a case in a child. Urol. Survey 4: 391, 1954. MedlineGoogle Scholar11. ABERNATHYPRICESPINK RSWEWW: Chronic brucellar pyelonephritis simulating tuberculosis. J. A. M. A. 159: 1534, 1955. CrossrefMedlineGoogle Scholar12. CROWTORMEYREDNERSULLIVAN JBDMWJBH: Caseation necrosis in human brucellosis. Amer. Rev. Tuberc. 67: 859, 1953. Google Scholar13. WEEDDABLINPUGHIVINS LADCDGJC: Brucella in tissues removed at surgery. Amer. J. Clin. Path. 22: 10, 1952. CrossrefMedlineGoogle Scholar14. WEEDSLOSSCLAGETT LAPTOT: Chronic localized pulmonary brucellosis. J. A. M. A. 161: 1044, 1956. CrossrefMedlineGoogle Scholar15. MCVAYGUTHRIEMICHELSONSPRUNT LFFIDDH: Isolation of brucella from apparently healthy individuals. Amer. J. Path. 25: 776, 1949. Google Scholar16. SCHWARZSILVERMANADRIANOSTAUBLEVINE JFNSMMS: The relation of splenic calcification to histoplasmosis. New Engl. J. Med. 252: 887, 1955. CrossrefMedlineGoogle Scholar17. SEVIANECKYSCHWARZ BJ: The incidence of splenic calcifications in positive reactors to histoplasmin and tuberculin. Amer. J. Roentgenol. 74: 53, 1956. Google Scholar18. SCHINZBOENSCHFRIEDLUEHLINGER HRWEEE: Roentgen-Diagnostics, 1st Amer. Ed., Grune & Stratton, New York, 1954, pp. 2289-2290. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Houston, TexasReceived for publication May 20, 1960.From the Departments of Medicine, Pathology, and Radiology, Baylor University College of Medicine, and the Ben Taub Infectious Disease Research Laboratory of the Jefferson Davis Hospital, Houston, Tex.Requests for reprints should be addressed to Ellard M. Yow, M.D., Professor of Medicine, Baylor University College of Medicine, Texas Medical Center, Houston, Tex. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByUne rate calcifiéeGastrointestinal BrucellosisMilzCase 40-1992Gastrointestinal brucellosisMilzHistoplasmosisHistoplasmosisBrucellosisKrankheiten durch BrucellenKrankheiten durch BrucellenActive splenic granuloma as a source of recurrent brucellosisPunctate calcifications of the spleen in sickle cell anemia 1 August 1961Volume 55, Issue 2Page: 307-313KeywordsBrucellosisCalciumGranulomasHospital medicineInflammationKidneysLiverPathology and laboratory medicineResearch laboratoriesSpleen Issue Published: 1 August 1961 PDF DownloadLoading ...