tbuckley/cabot-search huggingface dataset:
Max Brödel: The Man Who Put Art Into Medicine
Authors: John E. Skandalakis
Journal: JAMA (1992)

This is a fascinating biography, a biography full of art and science, anatomy and surgery. As Albrecht von Haller deemed Herman Boerhaave the "communis Europe praeceptor" (teacher of the whole of Europe), I would call Max Brödel of Johns Hopkins the teacher of the entire United States for medical illustration. I would need pages and pages to name his students and the students of his students. At a remove, Brödel spread the real art of medical education all over the country, including to my own medical school, in the person of Kathleen MacKay. Brödel's first book,<i>The Vermiform Appendix and Its Diseases</i>(1905), by Kelly and Hurdon, came to my attention in the late 1950s. I still have it, with its 827 pages and 398 figures, 117 of them by Brödel, and I still admire the authors' and Brödel's art. Medical illustration has a long history. If we consider
Percutaneous Biopsy of the Transplanted Kidney
Authors: Veerasamy K. G. Pillay
Journal: JAMA (1973)

One hundred forty percutaneous renal biopsies were done on the transplanted kidneys of 45 patients under television-monitored fluoroscopy. Insufficient tissue was obtained on six occasions; rebiopsy was successful in all instances. Thirteen patients developed macroscopic hematuria postbiopsy, but none required transfusion or nephrectomy. This procedure is safe and associated with a high yield. Open renal biopsy was performed on 20 patients. Macroscopic hematuria occurred in five patients, wound hematoma in two, and wound infection in three; thus, the incidence of complications was much higher following open biopsy.
Referral of Patients With Myocardial Infarction and Low Ejection Fraction to Arrhythmia Specialists
Authors: David C. Goff
Journal: JAMA (1996)

To the Editor.  —Despite Drs Stevenson and Ridker's 1 cautious interpretation of the likely benefit of routine referral of myocardial infarction survivors with low ejection fraction to arrhythmia specialists, the evidence on which they base their conclusion—Routine referral to arrhythmia specialists is not warranted for the majority of infarct survivors—points to an area of continuing difficulty in medical decision making. When are the benefits large enough to warrant application of an intervention?  Stevenson and Ridker construct models to estimate the potential effect of global treatment with amiodarone or an implantable defibrillator vs treatment of high-risk patients identified during screening by arrhythmia specialists. Their results suggest that 1 life could be saved for every 25 patients treated for 3.5 years if amiodarone were offered to every survivor of myocardial infarction with an ejection fraction less than 40%. Over the same period, 1 life might be saved for every 14 such patients
The Pill's Progress
Authors: Bernard Notes
Journal: JAMA (1969)

To the Editor:—  Your weak, erudite, supercilious editorial (206: 124, 1968) questioning whether complications occur if they occur at all in the use of the pill is pitifully inadequate.  practicing physician mustnotof necessity rely on scientists in his estimate of complications from the use of the pill. Such is the push (in recognition of the great need for population limitation) that a fervent religiosity has developed in its use (it isso easy). The clinician mustnot, at the peril of susceptible patients repeat stereotyped answers currently favored by editorial opinions, paraphrasing your editorial.  pill at the very least needs observations for caution, in view of the many thousands ofclinicalreports of its bad side effects and serious complications.  There are none so blind as those who will not see.  I wonder whether you dare publish this letter.
Fuseli's Nightmare
Authors: George E. Ehrlich
Journal: JAMA (1969)

<h3>To the Editor:—</h3> "The Nightmare" by Henry Fuseli illustrates a superstition prevalent in mountainous Central Europe. The inhabitants of Switzerland and western Austria believe it is unwholesome to sleep on one's back; trolls, known as Druden, heavily ascend the midnight stair to crouch on the chest of the sleeper. The resulting oppression prevents outcry and results in the symptoms which Dr. Schneck has so aptly described in his special report. As there are no horses in the legend, it is likely that the depicted mare was added later as stated.
Blood Pressure as a Cardiovascular Risk Factor
Authors: William B. Kannel
Journal: JAMA (1996)

- To examine the prevalence, incidence, predisposing factors for hypertension, its hazards as an ingredient of the cardiovascular risk profile, and the implications of this information for prevention and treatment.- Prospective longitudinal analysis of 36-year follow-up data from the Framingham Study of the relation of antecedent blood pressure to occurrence of subsequent cardiovascular morbidity and mortality depending on the metabolically linked burden of associated risk factors.- Hypertension is one of the most prevalent and powerful contributors to cardiovascular diseases, the leading cause of death in the United States. There is, on average, a 20 mm Hg systolic and 10 mm Hg diastolic increment increase in blood pressure from age 30 to 65 years. Isolated systolic hypertension is the dominant variety. There is no evidence of a decline in the prevalence of hypertension over 4 decades despite improvements in its detection and treatment. Hypertension contributes to all of the major atherosclerotic cardiovascular disease outcomes increasing risk, on average, 2- to 3-fold. Coronary disease, the most lethal and common sequela, deserves highest priority. Hypertension clusters with dyslipidemia, insulin resistance, glucose intolerance, and obesity, occurring in isolation in less than 20%. The hazard depends on the number of these associated metabolically linked risk factors present. Coexistent overt cardiovascular disease also influences the hazard and choice of therapy.- The absence of a decline in the prevalence of hypertension indicates an urgent need for primary prevention by weight control, exercise, and reduced salt and alcohol intake. The urgency and choice of therapy of existing hypertension should be based on the multivariate cardiovascular risk profile that more appropriately targets hypertensive persons for treatment and prevention of cardiovascular sequelae.
Stomatocytosis is absent in 'stomatin'-deficient mouse red cells
Authors: Yiwen Zhu, Chris Paszty, Tikva Turetsky, Susan Tsai, Frans A. Kuypers, Gloria Lee, Philip Cooper, Patrick G. Gallagher, Mary E. Stevens, Edward Rubin, Narla Mohandas, William C. Mentzer
Journal: Blood (2001)
Differentialdiagnose neurologischer Krankheitsbilder.
Authors: W. R. Kirschbaum
Journal: JAMA (1963)

This is the second edition, enlarged and revised, of a comprehensive textbook which has become a prominent work of present-day German medical literature. That at present Italian, French, and Spanish translations have been prepared indicates its recognition beyond the realm of German-speaking physicians. Lucidly written, it is a concise, unified approach to neurological differential diagnosis. The first section encompasses the differential diagnosis of the peripheral nervous system. The second main section covers with unusual completeness the circulatory, inflammatory, space-occupying, metabolic-degenerative, developmental, toxic-poisonous, and traumatic conditions. Though the presentation firmly centers on differential diagnosis, therapeutic procedures and prognosis are alluded to. In a third section the neuromuscular diseases, and those of the spinal column and cranium and of the endocrine system, are discussed. In a fourth section occurs a justified digression from the previous grouping according to disease entities, when the authors devote separate chapters of four selected "leading" symptoms: headaches,
Concealed breast cancer causes delayed treatment
Authors: R. Ahmed, G R McLatchie
Journal: BMJ (1998)

EDITOR—Nosarti et al suggested that delay by patients accounts for a large part of the time till treatment for breast cancer is started.1 We agree that this delay is an important problem; it is not often analysed as policies are targeted at earlier treatment of small lesions. Iversen et al considered a delay of eight weeks by patients to be a challenge to health services.2

We investigated the incidence of concealed breast cancer at Hartlepool General Hospital between January …
Recurrent Idiopathic Jaundice of Pregnancy
Authors: Melvin J. King, Joseph F. Kerrins
Journal: New England Journal of Medicine (1963)

ON rare occasions during the latter part of pregnancy, jaundice that is not related to primary liver disease, biliary-tract disease or hemolytic jaundice develops. The cause is not known. The jaundice occurs only with pregnancy, clears rapidly after delivery and tends to recur with subsequent pregnancies. Pruritus is usually a prominent feature, but symptoms are otherwise minimal. The health of the patient does not deteriorate, and the pregnancy is usually uncomplicated. The incidence of premature delivery, however, may be higher than normal. The laboratory studies are consistent with an obstructive jaundice. Liver biopsy reveals bile stasis in the bile canaliculi. . . .
Who Sets the Global Health Research Agenda? The Challenge of Multi-Bi Financing
Authors: Devi Sridhar
Journal: PLoS Medicine (2012)

As part of a cluster of articles critically reflecting on the theme of "no health without research," Devi Sridhar discusses a major challenge in the governance of research funding: "multi-bi" financing that allows the priorities of funding bodies to dictate what health issues and diseases are studied.
A Text-Book of X-Ray Diagnosis, vol 3: The Respiratory System
Authors: Robert N. Cooley
Journal: JAMA (1973)

The first edition of this compendium of x-ray diagnosis appeared in 1938. Over the years, there has been a remarkable continuity in authorship and considerable conformity in style, arrangements, and format of the several volumes. The present volume on the respiratory system has been enlarged by about 100 pages over the previous edition published in 1957. One new chapter has been added, namely "Mediastinal Tumours." There have been only modest expansions of the chapters on emphysema, fungal disease, the collagen diseases, and the pneumonias. The desirable features of this volume are the same as those for previous editions, especially the clarity and terseness of style that make for easy reading. The illustrations, although not profuse, are well chosen and clearly demonstrate the points made in the accompanying text. The sections prepared by Sir Peter Kerley are particularly distinctive for their shrewd insight and they reflect his vast experience in roentgenographic
Osteoporosis and immunosuppression in multiple myeloma.
Authors: A. M. Farrell, R. J. Powell
Journal: BMJ (1989)

depend on valproate for optimal control of their seizures throughout the childbearing years.5It is clearly of enormous importance that women with primary generalised epilepsies are differentiated from those with partial epilepsy, who will be best managed with carbamazepine.They are a group requiring specific counselling of the small risks of valproate to any pregnancy and needing screening of any pregnancy for neural tube defects within the first trimester.Patients themselves can probably best decide whether they wish to take the most effective drug and accept a small risk of neural tube defect or to take a less optimal drug that might be somewhat safer in pregnancy.
the white bow
Authors: Andrew Thurston
Journal: JAMA (2013)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Fungal infection of skin and nails by Hendersonula toruloidea
Authors: C.K. CAMPBELL, AZIZ KURWA, A-H.M. ABDEL-AZIZ, C. HODGSON
Journal: British Journal of Dermatology (1973)

Journal Article Fungal infection of skin and nails by Hendersonula toruloidea Get access C.K. CAMPBELL, C.K. CAMPBELL MRC Unit on the Experimental Pathology of the Skin, The Medical School, The University, Birmingham 15 and The Skin Hospital, Birmingham 15 Search for other works by this author on: Oxford Academic Google Scholar AZIZ KURWA, AZIZ KURWA MRC Unit on the Experimental Pathology of the Skin, The Medical School, The University, Birmingham 15 and The Skin Hospital, Birmingham 15 Search for other works by this author on: Oxford Academic Google Scholar A‐H.M. ABDEL‐AZIZ, A‐H.M. ABDEL‐AZIZ MRC Unit on the Experimental Pathology of the Skin, The Medical School, The University, Birmingham 15 and The Skin Hospital, Birmingham 15 Search for other works by this author on: Oxford Academic Google Scholar C. HODGSON C. HODGSON MRC Unit on the Experimental Pathology of the Skin, The Medical School, The University, Birmingham 15 and The Skin Hospital, Birmingham 15 Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 89, Issue 1, 1 July 1973, Pages 45–52, https://doi.org/10.1111/j.1365-2133.1973.tb01916.x Published: 01 July 1973 Article history Accepted: 05 January 1973 Published: 01 July 1973
Efficacy and Safety of Edifoligide
Authors: Nimesh D. Desai, Stephen E. Fremes
Journal: JAMA (2006)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Review: Systemic corticosteroids reduce treatment failure but increase hyperglycemia in COPD exacerbations
Authors: Paul Jones
Journal: Annals of Internal Medicine (2015)

ACP Journal Club17 March 2015Review: Systemic corticosteroids reduce treatment failure but increase hyperglycemia in COPD exacerbationsPaul Jones, MBBSPaul Jones, MBBSSt. George's, University of London, London, England, UK (P.J.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/ACPJC-2015-162-6-006 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Source CitationWalters JA, Tan DJ, White CJ, et al. Systemic corticosteroids for acute exacerbations of chronic obstructive pulmonary disease. Cochrane Database Syst Rev. 2014;9:CD001288. https://pubmed.ncbi.nlm.nih.gov/25178099Clinical Impact RatingsGIM/FP/GP: Emergency Med: Hospitalists: Pulmonology: Reference1. Leuppi JD, Schuetz P, Bingisser R, et al. Short-term vs conventional glucocorticoid therapy in acute exacerbations of chronic obstructive pulmonary disease: the REDUCE randomized clinical trial. JAMA. 2013;309:2223-31. [PMID: 23695200] Google Scholar Author, Article, and Disclosure InformationAffiliations: St. George's, University of London, London, England, UK (P.J.)This article was published at Annals.org on 3 March 2015. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByRationale and design of REGULATE: an observational study protocol for relationship between plasma metabolome and the efficacy of systemic glucocorticoid in acute exacerbation of chronic obstructive pulmonary disease 17 March 2015Volume 162, Issue 6Page: JC6KeywordsChronic obstructive pulmonary diseaseHyperglycemiaOutpatient clinicsOutpatientsPatientsPulmonary medicineVentilators ePublished: 17 March 2015 Issue Published: 17 March 2015 CopyrightCopyright © 2015 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...
Xanthelasmata, arcus corneae, and ischaemic vascular disease and death in general population: prospective cohort study
Authors: M. Christoffersen, R. Frikke-Schmidt, P. Schnohr, G. B. Jensen, B. G. Nordestgaard, A. Tybjaerg-Hansen
Journal: BMJ (2011)

<b>Objective</b> To test the hypothesis that xanthelasmata and arcus corneae, individually and combined, predict risk of ischaemic vascular disease and death in the general population. <b>Design</b> Prospective population based cohort study. <b>Setting</b> The Copenhagen City Heart Study. <b>Participants</b> 12 745 people aged 20-93 years free of ischaemic vascular disease at baseline and followed from 1976-8 until May 2009 with 100% complete follow-up. <b>Main outcome measures</b> Hazard ratios for myocardial infarction, ischaemic heart disease, ischaemic stroke, ischaemic cerebrovascular disease, and death; odds ratios for severe atherosclerosis. <b>Results</b> 563 (4.4%) of participants had xanthelasmata and 3159 (24.8%) had arcus corneae at baseline. During 33 years' follow-up (mean 22 years), 1872 developed myocardial infarction, 3699 developed ischaemic heart disease, 1498 developed ischaemic stroke, 1815 developed ischaemic cerebrovascular disease, and 8507 died. Multifactorially adjusted hazard/odds ratios for people with versus those without xanthelasmata were 1.48 (95% confidence interval 1.23 to 1.79) for myocardial infarction, 1.39 (1.20 to 1.60) for ischaemic heart disease, 0.94 (0.73 to 1.21) for ischaemic stroke, 0.91 (0.72 to 1.15) for ischaemic cerebrovascular disease, 1.69 (1.03 to 2.79) for severe atherosclerosis, and 1.14 (1.04 to 1.26) for death. The corresponding hazard/odds ratios for people with versus those without arcus corneae were non-significant. In people with versus those without both xanthelasmata and arcus corneae, hazard/odds ratios were 1.47 (1.09 to 1.99) for myocardial infarction, 1.56 (1.25 to 1.94) for ischaemic heart disease, 0.87 (0.57 to 1.31) for ischaemic stroke, 0.86 (0.58 to 1.26) for ischaemic cerebrovascular disease, 2.75 (0.75 to 10.1) for severe atherosclerosis, and 1.09 (0.93 to 1.28) for death. In all age groups in both women and men, absolute 10 year risk of myocardial infarction, ischaemic heart disease, and death increased in the presence of xanthelasmata. The highest absolute 10 year risks of ischaemic heart disease of 53% and 41% were found in men aged 70-79 years with and without xanthelasmata. Corresponding values in women were 35% and 27%. <b>Conclusion</b> Xanthelasmata predict risk of myocardial infarction, ischaemic heart disease, severe atherosclerosis, and death in the general population, independently of well known cardiovascular risk factors, including plasma cholesterol and triglyceride concentrations. In contrast, arcus corneae is not an important independent predictor of risk.
THE EFFECT OF MESCALINE ON DIFFERENTIATED CONDITIONAL REFLEXES
Authors: WAGNER H. BRIDGER, W. HORSLEY GANTT
Journal: American Journal of Psychiatry (1956)

Mescaline produced an inhibitory state accompanied by a schizokenesis or dissociation of systems. This disharmony was also manifested in that the CS appeared to act in the same manner as the US. On this basis a neurodynamic theory of the mechanism of mescaline's actions is postulated: that under mescaline intoxication and in some mental illnesses, a dissociation of the second and first signaling systems and the unconditional reflexes occurs in which each signaling system acts as if it were the same as the more primitive system on which it is based. The secondary signals—words and ideas—come to act like the primary signals of sensations and direct impressions of reality. This theory may help explain certain psychological phenomena, e.g. dreams, hysteria, compulsions, delusions, and hallucinations. While the content of these phenomena depends on the personality of the subject and all the environmental factors that determine this personality, their mechanisms are physiological, regardless of whether one prefers a pathophysiologic or psychogenic etiology. Based on our experimental findings and the work of others, a neurodynamic pathogenesis of the psychological effects of mescaline is described.
Peanuts in Infants: Inhalants as Well as Allergens
Authors: Dodi Schultz
Journal: JAMA (1989)

<h3>To the Editor.—</h3> I was surprised by the reply by Dr Sampson<sup>1</sup>to the letter asking about the introduction of various foods in children's diets. Granted, the inquirer apparently was concerned about the role of these foods as allergens, but a suggestion that all the listed foods be excluded "for the first two years of life in the `high-risk' infant" falls short when it comes to one of those foods. Most pediatricians agree that nuts should be excluded from the diet for the first 4 to 5 years of life because they are aspirated easily, and every child, whether or not there is a familial history of hypersensitivity, is at high risk. I believe that this point should have been included, for safety's sake.
Paper or Screen, Mother Tongue or English: Which Is Better?
Authors: Pål Gulbrandsen, Torben V. Schroeder, Josef Milerad, Magne Nylenna
Journal: JAMA (2002)

To compare family physicians' ability to retain information when reading a review article on paper vs on screen, and in their mother tongue vs in English.Randomized trial of 114 Scandinavian family physicians who read a review article in October or November 2000 from the Journal of Trauma for 10 minutes either on paper and in English, on screen and in English, on paper in their mother tongue, or on screen in their mother tongue. To assess comprehension, they immediately completed a questionnaire with 6 open questions about 13 key facts from the review article. Sum score was on a scale from 0 (no correct answers) to 13 points (all questions answered correctly).There was no significant difference between readers of paper vs screen versions, with a median (interquartile range [IQR]) of 4 (2-6) vs 4 (2-5), respectively (P =.97). Physicians who read in their mother tongue scored significantly higher than those who read in English, with a median (IQR) of 4 (3-6) vs 3 (2-4) (P =.01).The medium (paper vs screen) did not influence the ability of family physicians to retain medical information. They best retained medical information when reading in their mother tongue.
MONOCLONAL ANTI-HLA-B27 ANTIBODY (B27M1): PRODUCTION AND LACK OF DETECTABLE TYPING DIFFERENCE BETWEEN PATIENTS WITH ANKYLOSING SPONDYLITIS, REITER'S SYNDROME, AND NORMAL CONTROLS
Authors: F.Carl Grumet, BrianM. Fendly, EdgarG. Engleman
Journal: The Lancet (1981)