Hypogonadotrophic Hypogonadism Simulating Turner's Syndrome
Authors: ABNER J. DELMAN
Journal: Annals of Internal Medicine (1961)

Case Reports1 September 1961Hypogonadotrophic Hypogonadism Simulating Turner's SyndromeABNER J. DELMAN, M.D., JEROME G. PORUSH, M.D., ALVIN D. SCHWARTZ, M.D.ABNER J. DELMAN, M.D.Search for more papers by this author, JEROME G. PORUSH, M.D.Search for more papers by this author, ALVIN D. SCHWARTZ, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-55-3-471 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe clinical manifestations of panhypopituitarism secondary to destruction of the adenohypophysis are well known. After its original description by Simmonds (1) in 1914, panhypopituitarism was the subject of many case reports and reviews (2-5). Marked insufficiency of the target glands and profound cachexia were stressed. Sheehan and Murdoch (6, 7) first emphasized that most patients with pituitary insufficiency are not cachetic and that there is a wide clinical spectrum of pituitary dysfunction. Hypopituitarism may vary from mild involvement of one or more of the target glands to severe insufficiency of all three principal organs (6-8). The clinical course may range...References1. SIMMONDS M: Ueber Hypophysesschwiend mit todlichen augang. Deutsch. Med. Wschr. 40: 322, 1914. CrossrefGoogle Scholar2. CALDER RM: Anterior pituitary insufficiency (Simmonds' disease). Bull. Johns Hopkins Hosp. 50: 87, 1932. Google Scholar3. SILVER S: Simmonds' disease. Arch. Intern. Med. 51: 175, 1933. CrossrefGoogle Scholar4. HERRICK WW: Clinical features of hypophyseal cachexia. Ass. Res. Nerv. Dis. Proc. 17: 609, 1938. Google Scholar5. ESCAMILLALISSER RFH: Simmonds' disease. J. Clin. Endocr. 2: 65, 1942. CrossrefGoogle Scholar6. SHEEHAN HL: Post partum necrosis of anterior pituitary. Lancet 1: 817, 1939. Google Scholar7. 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(c) GRUMBACH, M. M., BARR, M. L.: Cytologic tests of chromosomal sex in relation to sexual anomalies in man. Recent Progr. Hormone Res. 14: 255, 1958. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.Received for publication August 17, 1960.From the Departments of Medicine and Endocrinology, The Mount Sinai Hospital, New York, N. Y.Requests for reprints should be addressed to Abner J. Delman, M.D., Montefiore Hospital, 210th Street and Bainbridge Avenue, New York 67, N. Y. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byHypogonadotropic Hypogonadism Associated with Anosmia in the Female 1 September 1961Volume 55, Issue 3Page: 471-478KeywordsEndocrinologyHospital medicineHypogonadismPanhypopituitarismTurner syndrome Issue Published: 1 September 1961 PDF downloadLoading ...