tbuckley/cabot-search huggingface dataset:
Amoebiasis--a Diagnostic Problem in Great Britain
Authors: R. Wright
Journal: BMJ (1966)

and Mollin, 1957).Hawkins and Meynell (1958) did not find significantly low levels of serum vitamin B12 in their patients.Lees (1961) noted that some patients developed low serum vitamin-B12 levels, and he showed that the absorption of radioactive vitamin B,2 improved during treatment with folic acid.The finding of a significant lowering of the level of vitamin B12 in our patients would confirm the suggestion of Lees that a functional change occurs in the gut wall, for in our cases there was no indication of a dietary deficiency in vitamin B,2.It is possible either that anticonvulsants affect the absorption of vitamin B12 per se or that a deficiency of folic acid impairs vitamin-B12 absorption. SummaryHaematological studies on a randomly selected group of epileptic patients on anticonvulsants have demonstrated an incidence of macrocytosis in 11% and of low serum folic-acid levels in 37%.Compared with a group of normal control subjects these patients had significantly low levels of serum folic acid and some reduction in serum vitamin B12* This study confirms that the primary cause of these phenomena is the anticonvulsant therapy, but comparison with previous surveys and with a group of less well nourished subjects suggests that an adequate diet may protect against the occurrence of macro- cytosis.
STANDARDS OF PRACTICE OF INTERNAL MEDICINE AND METHODS OF ASSESSING THE QUALITY OF PRACTICE IN HOSPITALS
Authors: MARION A. BLANKENHORN
Journal: Annals of Internal Medicine (1957)

Editorial1 August 1957STANDARDS OF PRACTICE OF INTERNAL MEDICINE AND METHODS OF ASSESSING THE QUALITY OF PRACTICE IN HOSPITALSMARION A. BLANKENHORN, M.D.MARION A. BLANKENHORN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-47-2-367 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptA study of this problem was initiated by the Regents of the American College of Physicians through a committee on Accreditation of Hospitals in Medicine,1not the Joint Commission on Accreditation. The committee elected to study the problem by surveying hospitals as a pilot study of present criteria and standards. The committee procured a Director who was to serve for one year,2but the committee functioned throughout in an advisory capacity. It was the purpose of the committee to "develop ways and means to define an acceptable standard for use by the Joint Commission on Accreditation, and secondly to judge...1 Colwell AR Eisele CW Ferris EB Kinsman JM Luckey EH, M.D., Chicago, Chairman; , M.D., Denver; , M.D., New York;, M.D., Louisville; and , M.D., New York. Google Scholar2 Blankenhorn MA, M.D., Cincinnati. Google Scholar3 Almy T Bunn W Burgess A Garon M Kaufman J Leonard JC McCarthy J McGlone F Minish L Poindexter SM Rash JO Schnabel T Schnitker M Smyth C Stewart F Strauss M Colwell A Eisele CW Ferris E Kinsman M, M.D., , M.D., , M.D., , M.D., , M.D., , M.D., , M.D., , M.D., , M.D., , M.D., , M.D., , M.D., , M.D., , M.D., , M.D., , M.D., , M.D., , M.D., , M.D., , M.D. Google Scholar4 EiseleSleeHoffmann CWVNRG: Can the practice of internal medicine be evaluated? Ann. Int. Med. 44: 144-161 (Jan.) 1956. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: MARION A. BLANKENHORN, M.D. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAuditing the quality of care in emergency departmentsSTANDARDS OF PRACTICE OF INTERNAL MEDICINE: METHODS OF JUDGING ITS QUALITY IN HOSPITALS*ARTHUR R. COLWELL SR., M.D., GEORGE KARL FENN, M.D.PROGRESS REPORT COMMITTEE FOR THE STUDY OF HOSPITAL STANDARDS IN MEDICINEG. KARL FENN, M.D. 1 August 1957Volume 47, Issue 2 Page: 367-374 Keywords Hospital medicine Pilot studies ePublished: 1 December 2008 Issue Published: 1 August 1957 PDF downloadLoading ...
Prognosis in Dissecting Aneurysm of the Aorta
Authors: FRED M. KUIPERS, IRWIN J. SCHATZ
Journal: Circulation (1963)

Of 26 patients with dissecting aneurysm of the aorta diagnosed at the Henry Ford Hospital from 1950 through 1962, 13 patients lived less than six weeks from the time of initial diagnosis. Of the other 13 patients, 2 had had successful operative repair of the aneurysm during the acute stage. The average survival of the remaining 11 patients was 26 months. Prognosis of this unselected group of patients was better than has been reported previously for this disease. No significant correlation could be found between survival of the patient and the presence of past hypertension, associated recognized cardiovascular disease, or site of intimal rupture.
Hyperosmotic non-ketotic diabetic syndrome precipitated by treatment with diuretics
Authors: T H Hughes-Davies
Journal: BMJ (1982)

interview after an emergency referral she presented many biological symptoms and signs of depression.For three weeks, attempts were made to treat her with antidepressants as an outpatient, but she was admitted to inpatient psychiatric care after becoming acutely agitated and violent at home.Failure to respond to a combination of tetracyclic antidepressants and phenothiazines lead to the application of electric convulsion treatment four times.She made an excellent response, and was fit for discharge to outpatient care after six weeks as an inpatient.The social factors included profound language difficulties, leading to marked social isolation, aggravated by the lack of extended family support together with profound disappointment at the delivery of a fifth daughter.
Influence of Smoking on Treatment With Clopidogrel
Authors: Dirk Sibbing, Willibald Hochholzer, Adnan Kastrati
Journal: JAMA (2012)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
MAINTAINING LENGTH AND POSITION IN THE TREATMENT OF COMPOUND FRACTURES
Authors: H. WINNETT ORR
Journal: JAMA (1924)

The importance of maintaining length and position in the treatment of compound fractures is in many cases overlooked by the surgeon in the supposed interest of wound treatment. This accounts for many of the cases of malunion of the fragments, shortening of the limb, unduly prolonged deformity and disability which can only be partially corrected by secondary operation. Such extensions of the period of convalescence, economic loss to the community and additional medical and hospital expense are factors of equal importance to all, but have attracted attention particularly in the treatment of those injured in industrial occupations. These facts have been impressed on us as we are called on frequently to examine and treat such cases months or even years after the accident has occurred. We see disabilities of from 50 per cent. to complete loss of normal function after compound fractures, with angular and overriding deformities of bone, or
FUSION OPERATION ON THE FOOT
Authors: A. BRUCE GILL
Journal: JAMA (1927)

Fusion of two or more bones of the foot is done to correct deformity and stabilize the foot or to relieve pain, in order that the individual may the better stand and walk. Arthrodesis, or surgical ankylosis, of a joint appears to be destructive instead of constructive; but experience has taught that it is often the only means to maintain correction of a deformity and to hold the foot in the best position for function. Part of the flexibility of the foot is sacrificed to secure an efficient stability, which is so essential for weight bearing and locomotion. Joint motion is of little or no value if it cannot be controlled or if it is painful. Fortunately, there are so many joints in the foot that the loss of motion in any one does not too seriously impair the flexibility.  Arthrodesis of one or more joints of the foot is
The detection of coronary artery disease with radionuclide techniques: a comparison of rest-exercise thallium imaging and ejection fraction response.
Authors: J H Caldwell, G W Hamilton, S G Sorensen, J L Ritchie, D L Williams, J W Kennedy
Journal: Circulation (1980)

Fifty-two patients with suspected coronary artery disease underwent coronary angiography, thallium-201 myocardial imaging, and ECG-gated blood pool ventriculography at rest and at maximal exercise.In 11 patients without coronary artery disease, all thallium images were normal.The resting ejection fraction (EF) was normal in all 11 patients and increased during exercise in six, was unchanged in three, and decreased in two.Of the 41 patients with coronary artery disease, the thallium image was normal at rest and at exercise in six (15%), whereas the exercise EF was abnormal in these six.A new (18 patients) or enlarged (11 patients) defect appeared on the thallium image in 29 of 41 patients (71%) with coronary disease.Six of 41 patients (15%) had an abnormal rest thallium image that was unchanged with exercise.An abnormal rest and/or exercise image defect identified 35 of 41 patients (85%) with coronary artery disease.The resting EF was normal in 26 of the 41 patients (63%) and in 24 patients demonstrated an abnormal response to exercise.Fifteen patients (37%) had an abnormal resting EF, and 14 of these 15 demonstrated persistent abnormalities.Thus, an abnormal exercise EF response identified 38 of 41 (93%) patients with coronary disease.The specificity of the thallium image was 100% and for the exercise EF determination, 54% (p < 0.02).We conclude that an abnormal exercise EF response and the rest-exercise thallium image have similar sensitivities for detecting coronary disease; however, an abnormal exercise ejection fraction was significantly more sen- sitive than was a new thallium abnormality alone (93% vs 71%).Combined, the two studies detected all patients with coronary disease.
Obstetrics and Gynecology: A History and Iconography
Authors: Stuart W. Campbell
Journal: JAMA (1994)

The new version of Dr Speert's handsomely illustrated volume reflects the intellectual authority, reading pleasure, and excellent illustrations readers associate with the 1973 edition. The publisher's front matter advises that<i>Obstetrics and Gynecology: A History and Iconography</i>is now printed on acid-free paper with strong and durable binding materials. The publisher is to be congratulated for according Dr Speert's repository of copies of centuries of art and photography a quality of material that will extend its life. Such generosity should prove useful as well: my own medical school's library has had to repair the 1970s version. It is apparently heavily used and deserves the complement of production standards appropriate for books of lasting value. Obstetrics and gynecology seems well covered to this layman. Chapter headings, unchanged from the previous edition, run the same wide (though logical) gamut, from the first chapter, "The Female Anatomy," through chapter 19, "Obstetric and Gynecologic
More Rough Notes for Lord Ashley
Authors: H. W. Livett
Journal: BMJ (1844)

prevent water passing through them from the ven- tricles, when water was poured into them, the heart being inverted, and the ventricles having been laid open (but it could not be doubted but that a considerable regurgitation took place through these open- ings during life).The semi-lunar valves, both of the aorta and of the pulmonary artery, were healthy.Abdomen.-Liver enlarged, and much congested in its venous hepatic system.Spleen, pancreas, stomach, and intestines, healthy.Kidneys congested and granu- lar.Other parts of the urinary apparatus healthy.
Induction of Cutaneous Squamous Cell Carcinomas by RAF Inhibitors: Cause for Concern?
Authors: Mario E. Lacouture, Kathryn O'Reilly, Neal Rosen, David B. Solit
Journal: Journal of Clinical Oncology (2011)

Article Tools UNDERSTANDING THE PATHWAY Article Tools OPTIONS & TOOLS Export Citation Track Citation Add To Favorites Rights & Permissions COMPANION ARTICLES No companion articles ARTICLE CITATION DOI: 10.1200/JCO.2011.38.2895 Journal of Clinical Oncology - published online before print November 7, 2011 PMID: 22067405 Induction of Cutaneous Squamous Cell Carcinomas by RAF Inhibitors: Cause for Concern? Mario E. LacouturexMario E. LacoutureSearch for articles by this author Kathryn O'ReillyxKathryn O'ReillySearch for articles by this author Neal RosenxNeal RosenSearch for articles by this author David B. SolitxDavid B. SolitSearch for articles by this author Show More Memorial Sloan-Kettering Cancer Center, New York, NYNew York University, New York, NYMemorial Sloan-Kettering Cancer Center, New York, NYMemorial Sloan-Kettering Cancer Center, New York, NY https://doi.org/10.1200/JCO.2011.38.2895 Full Text PDF Figures and Tables "Induction of Cutaneous Squamous Cell Carcinomas by RAF Inhibitors: Cause for Concern?." Journal of Clinical Oncology, 30(3), pp. 329–330© 2011 by American Society of Clinical Oncology
Dermatome shaving of psoriasis
Authors: J.J. ELBERG, F. BRANDRUP
Journal: British Journal of Dermatology (1987)

Dermatome shaving was performed in 20 patients with chronic recalcitrant plaque psoriasis. The level of shaving was just beneath the superficial dermal vascular plexus. Healing was achieved in 2 weeks. After 1 year, six patients had shown no recurrence; 10 patients had a few guttate elements in the shaved area, while four patients had significant recurrence. Recurrences were related to residual acanthotic epidermis left after shaving. A general recommendation of surgical treatment for psoriasis would be hazardous on the basis of these results. However, shaving may constitute an alternative treatment of recalcitrant plaques of limited extent.
554 T REGULATORY LYMPHOCYTES (T-REGS) IMPAIR EFFICIENT CONTROL OF HBV REPLICATION BY CURBING HBV-SPECIFIC T HELPER TYPE 1 RESPONSES
Authors: I. Carey, D. Cebecauerova, M.S. Longhi, S. Bansal, P. Subramaniam, G. Mieli-Vergani, D. Vergani
Journal: Journal of Hepatology (2009)
Response to Open Peer Commentaries on “Ritual Male Infant Circumcision and Human Rights”
Authors: Allan J. Jacobs, Kavita S. Arora
Journal: The American Journal of Bioethics (2015)

Click to increase image sizeClick to decrease image size Notes1 . UDHR, Article 16, reads, in full:(1) Men and women of full age, without any limitation due to race, nationality or religion, have the right to marry and to found a family. They are entitled to equal rights as to marriage, during marriage and at its dissolution.(2) Marriage shall be entered into only with the free and full consent of the intending spouses.(3) The family is the natural and fundamental group unit of society and is entitled to protection by society and the State.2 . ECHR, Article 16, reads, in full, “No one shall be subjected to torture or to inhuman or degrading treatment or punishment.”3 . Central Rabbinical Congress, a recent federal appellate decision, upheld the legality of circumcision, as did the regulation it overturned. The issue at hand was whether specific written consent was needed for a mohel (Jewish ritual circumciser) to aspirate blood from the infant's penis using his lips.4 . Van Howe does not state which group he is concerned about, but review of the composition of the panel reveals that a few of the eight panelists bear surnames or premarital surnames that frequently are held by Jews. The identity of the group with which van Howe is concerned is no more relevant to our discussion than it should have been to van Howe's.5 . That being said, there is no reason to believe that the Frisch group intended their comment about cultural bias as a dog whistle; unlike the van Howe comment, theirs seems only intended to contrast Americans with Europeans, and to assert the objectivity of the European perspective.
Exhaled Nitric Oxide and Impaired Oxygenation in Cirrhotic Patients before and after Liver Transplantation
Authors: Giovanni Rolla
Journal: Annals of Internal Medicine (1998)

Nitric oxide may be involved in the impaired oxygenation of cirrhotic patients, a condition that improves in most patients after liver transplantation.To compare oxygenation and nitric oxide concentrations before and after liver transplantation.Before-and-after observational study.Academic medical center.18 patients with cirrhosis and no obvious cardiopulmonary disease who underwent successful orthotopic liver transplantation.Orthotopic liver transplantation.Blood gas analysis, measurement of exhaled nitric oxide, contrast-enhanced echocardiography, and pulmonary function tests.Before transplantation, the mean (+/- SD) exhaled nitric oxide concentration was higher in patients than in normal controls (13 +/- 4.9 parts per billion [ppb] compared with 5.75 +/- 1.9 ppb; P < 0.001). After transplantation, the alveolar-arterial oxygen gradient significantly decreased (from 17.3 +/- 7.1 mm Hg to 9 +/- 5.2 mm Hg; P < 0.001), as did the exhaled nitric oxide concentration (from 13 +/- 4.9 ppb to 6.2 +/- 2.8 ppb; P < 0.001). The decrease in the exhaled nitric oxide concentration was significantly correlated with the decrease in the alveolar-arterial oxygen gradient (r = 0.56; P = 0.014). Five patients met the criteria for the diagnosis of the hepatopulmonary syndrome before transplantation; the syndrome was cured by transplantation.The correlation between the decrease in exhaled nitric oxide concentration after liver transplantation and the improvement in oxygenation reinforces the hypothesis that nitric oxide is an important mediator of impaired oxygenation in patients with cirrhosis.
Treatment of Multiple Sclerosis
Authors: Dale E. McFarlin
Journal: New England Journal of Medicine (1983)

No form of treatment has been demonstrated to alter the long-term course of multiple sclerosis. This is not because of lack of effort. From Charcot's time up to the present issue of the Journal,1 , 2 trials of hundreds of various treatments have been reported. A synopsis of the 120 therapeutic claims involving the disease was published last year by the International Federation of Multiple Sclerosis Societies.3 Only one substance, ACTH, has been shown in a controlled double-blind trial to shorten the duration of acute attacks of multiple sclerosis.4 Many physicians believe that steroids are equally effective, but this has not . . .
DIFFERENTIAL DIAGNOSIS BETWEEN COXA VAEA AND OTHER STATIC, INFLAMMATORY AND TRAUMATIC AFFECTIONS OF THE HIP JOINT.
Authors: NICHOLAS SENN
Journal: JAMA (1905)

The surgeon not infrequently meets with cases in which it is extremely difficult and sometimes impossible to make an early and positive differential diagnosis between the different forms of static, inflammatory and traumatic affections of the hip joint. The diagnosis of the different affections of the hip joint has gained much by the use of the Roentgen ray as one of our modern and most reliable diagnostic resources, and in obscure affections of the hip joint it should invariably be resorted to; in the majority of cases the information thus gained will forge the last link in the long chain of diagnostic reasoning by exclusion. Even this diagnostic aid, owing to the complicated structure of the hip joint, its deep location and diversity of function, will fail in some cases in clearing up the existing doubt. As an isolated diagnostic aid, it will not infrequently lead the surgeon astray in his search for a correct diagnosis.
The role of particulate size and chemistry in the association between summertime ambient air pollution and hospitalization for cardiorespiratory diseases.
Authors: R T Burnett, S Cakmak, J R Brook, D Krewski
Journal: Environmental Health Perspectives (1997)

In order to address the role that the ambient air pollution mix, comprised of gaseous pollutants and various physical and chemical measures of particulate matter, plays in exacerbating cardiorespiratory disease, daily measures of fine and coarse particulate mass, aerosol chemistry (sulfates and acidity), and gaseous pollution (ozone, nitrogen dioxide, sulfur dioxide, and carbon monoxide) were collected in Toronto, Ontario, Canada, in the summers of 1992, 1993, and 1994. These time series were then compared with concurrent data on the number of daily admissions to hospitals for either cardiac diseases (ischemic heart disease, heart failure, and dysthymias) or respiratory diseases (tracheobronchitis, chronic obstructive long disease, asthma, and pneumonia). After adjusting the admission time series for long-term temporal trends, seasonal variations, the effects of short-term epidemics, day of the week effects, and ambient temperature and dew point temperature, positive associations were observed for all ambient air pollutants for both respiratory and cardiac diseases. Ozone was least sensitive to adjustment for the gaseous and particulate pollution measures. However, the association between the health outcomes and carbon monoxide, fine and coarse mass, sulfate levels and aerosol acidity could be explained by adjustment for exposure to gaseous pollutants. Increases in ozone, nitrogen dioxide, and sulfur dioxide equivalent to their interquartile ranges corresponded to an 11% and 13% increase in daily hospitalizations for respiratory and cardiac diseases, respectively. The inclusion of any one of the particulate air pollutants in multiple regression models did not increase these percentages. Particle mass and chemistry could not be identified as an independent risk factor for the exacerbation of cardiorespiratory diseases in this study beyond that attributable to climate and gaseous air pollution. We recommend that effects of particulate matter on health be assessed in conjunction with temporally covarying gaseous air pollutants.