Unusual Manifestations of Syphilitic Cardiovascular Disease
Authors: J. H. BOSS
Journal: Annals of Internal Medicine (1961)

Case Reports1 November 1961Unusual Manifestations of Syphilitic Cardiovascular DiseaseJ. H. BOSS, M.D., M. LEFFKOWITZ, M.D., M. FREUD, M.D.J. H. BOSS, M.D.Search for more papers by this author, M. LEFFKOWITZ, M.D.Search for more papers by this author, M. FREUD, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-55-5-824 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe salient clinical and pathological features of syphilitic cardiovascular disease are well known, yet a unique case may still pose perplexing and intriguing problems. In the case reported, myxomatous degeneration of the cardiovascular connective tissue is the notable pathological finding. Myxomatous material, a normal body constituent, accumulates with increasing age and in certain pathological conditions in the heart and blood vessels (1, 2). The purpose of this report is to stress the anatomical and functional significance of myxomatous degeneration in syphilitic cardiovascular disease.CASE REPORTA 36-year-old sanitation worker was referred to this hospital because of "arthralgia." He had no...References1. BUNTINGBUNTING CHH: Acid mucopolysaccharides of the aorta. Arch. Path. 55: 257, 1953. Google Scholar2. SEREBRENNIKOVA EM: The role of the chromotope substance in the pathogenesis of cardiac fibrosis. Arkh. Pat. (Abstracted in General Pathology and Pathological Anatomy, Excerpta Med. 3: 93, 1950). Google Scholar3. RAEKALLIO J: Histochemical studies on idiopathic medionecrosis of the aorta. Arch. Path. 66: 733, 1958. Google Scholar4. GALLBENNETTBAUER EAGAW: Generalized hypertrophic osteoarthropathy: a pathologic study of seven cases. Amer. J. Path. 27: 349, 1951. MedlineGoogle Scholar5. BENDA C: Die Syphilis des Gefässystems, in Handbuch der Geschlechtskrankheiten, ed. by Finger, E., Jadassohn, J., Ehrmann, S., and Grosz, S., Alfred Hölder, Vienna, 1912, pp. 807-872. Google Scholar6. SMITHSAXTONFRITZ JRJAHC: Syphilitic cardiovascular disease combined with chronic endocardial lesions usually attributed to rheumatic fever. Amer. J.Med. 10: 37, 1951. CrossrefMedlineGoogle Scholar7. SAPHIR O: Syphilitic myocarditis. Arch. Path. 13: 266, 1932. Google Scholar8. ANDERSONPRATT-THOMAS MHR: Marfan's syndrome. Amer. Heart J. 46: 911, 1953. CrossrefMedlineGoogle Scholar9. SAPHIRSCOTT ORW: The involvement of the aortic valve in syphilitic aortitis. Amer. J. Path. 3: 527, 1927. MedlineGoogle Scholar10. JAFFÉ R: Die Anatomischen Veranderungen bei Syphilis in Venezuela. Schweiz. Med. Wschr. 79: 33, 1949. Google Scholar11. FERNEXFERNEX MC: La dégénerescence mucoide des valvules mitrales: ses répercussions fonctionnelles. Helv. Med. Acta 25: 694, 1958. MedlineGoogle Scholar12. FERNEX M: La dégénerescence mucoide de l'anneau fibreux: a propos de l'insufficance aortique fonctionnelle. Helv. Med. Acta 25: 208, 1958. MedlineGoogle Scholar13. VOGELBLUMENFELDGUTNER ASLB: Diagnostic significance of pulmonary hypertrophic osteoarthropathy. Amer. J. Med. 18: 51, 1955. CrossrefMedlineGoogle Scholar14. HAMMERSTEINO'LEARY JFJ: The features and significance of hypertrophic osteoarthropathy. Arch. Intern. Med. 99: 431, 1957. CrossrefGoogle Scholar15. DRESNERTROMBLY EP: The latex-fixation reaction in nonrheumatic diseases. New Engl. J. Med. 261: 981, 1959. CrossrefMedlineGoogle Scholar16. WEINMANNSICHER JPH: Bone and Bones: Fundamentals of Bone Biology, C. V. Mosby Co., St. Louis, 1955, p. 300. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: J. H. BOSS, M.D.; M. LEFFKOWITZ, M.D.; M. FREUD, M.D.Affiliations: Petah Tiqva,From the Department of Pathology and the Medical Service "A," Beilinson Hospital, Petah Tiqva, Israel.Requests for reprints should be addressed to Jochanan H. Boss, M.D., Department of Pathology, Massachusetts General Hospital, Boston 14, Massachusetts. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAllgemeine ÜbersichtMyokarditis bei Infektionskrankheiten 1 November 1961Volume 55, Issue 5Page: 824-831KeywordsArthritisBlood vesselsCardiovascular diseasesConnective tissueEdemaHeartHypergammaglobulinemiaMedical servicesSanitationSyphilis ePublished: 1 December 2008 Issue Published: 1 November 1961 PDF downloadLoading ...