tbuckley/cabot-search huggingface dataset:
Personal Pediatrician: Peace of Mind for Caring Parents
Authors: Ray van Wolkenten
Journal: JAMA (1994)

Personal Pediatricianis an interactive program designed to offer parents guidance in the handling of common pediatric problems. Conditions are grouped in four categories: accidents, general, skin problems, and newborns. There is also a general index of over 350 items. The user identifies a complaint such as headache and is then led through a series of questions that help classify the complaint, determine the seriousness, and advise appropriate care, including referral to physician or emergency department as indicated. For example, the interaction for headache asks questions that consider trauma, meningitis, sinus infection, allergy, and minor headaches, and suggests appropriate referrals to physician, emergency care, or home remedies.  The program is easily as good as many books available and has the advantage of carrying the user through a series of questions interactively. The ability to use the electronic index to find the area
Shortening of Fibrillatory Cycle Length in the Pulmonary Vein During Vagal Excitation
Authors: Yoshihide Takahashi, Pierre Jaïs, Mélèze Hocini, Prashanthan Sanders, Martin Rotter, Thomas Rostock, Li-Fern Hsu, Frédéric Sacher, Jacques Clémenty, Michel Haïssaguerre
Journal: Journal of the American College of Cardiology (2006)
An assessment of the validity of spectral entropy as a measure of sedation statein mechanically ventilated critically ill patients
Authors: Timothy S. Walsh, Pamela Ramsay, T. Petteri Lapinlampi, Mika O. K. Särkelä, Hanna E. Viertiö-Oja, Pekka T. Meriläinen
Journal: Intensive Care Medicine (2007)
Aphthous ulcers and folate.
Authors: B. D. Birt, J. H. Mather
Journal: BMJ (1968)

cover, or that loose or infected teeth were involved ?If the treatment provided was only fillings performed in a sound mouth would the authors consider that the relation- ship of dental treatment to the onset of the disease might be fortuitous, especially since it was not possible to isolate the causative organisms to give further evidence ?The answer to this question is of great importance in view of the number of patients for whom dental surgeons routinely provide an antibiotic umbrella before the removal of teeth, but not before filling them.-Iam, etc.,
Moral Concerns and the Willingness to Donate to a Research Biobank
Authors: Tom Tomlinson, Raymond De Vries, Kerry Ryan, Hyungjin Myra Kim, Nicole Lehpamer, Scott Y. H. Kim
Journal: JAMA (2015)

Research biobanks are increasing in number and importance, with great potential for advancing knowledge of human health, disease, and treatment.1 Recruitment of donors is vital to their success and relies largely on blanket consent, in which donors give one-time permission for any future research uses of their coded specimen. This approach to consent has been endorsed recently in proposed changes to federal regulations.2

Previous studies suggest that donors may have moral, religious, and cultural concerns about the use to which their specimens are put, which may affect their willingness to give blanket consent.3,4 These earlier studies, however, used convenience samples unrepresentative of the US population.
TCT-546 Predictors and Implications of Subintimal Tracking During Endovascular Revascularization of Chronic Total Occlusions in the Infrainguinal Arteries
Authors: Atif Mohammad, Karan Sarode, Seth Jelinek, Karthik D. Mekala, Ariel Vinas, Avantika Banerjee, Purav Mody, Swagata Das, Donald Williams, Osvaldo Gigliotti, Andrew Klein, Anand Prasad, Emmanouil Brilakis, Subhash Banerjee
Journal: Journal of the American College of Cardiology (2014)
Inadvertent Is Unintentional
Authors: Harry L. Arnold
Journal: JAMA (1985)

To the Editor.—  Despite Dr Mayhew 1 and Webster's Third New International Dictionary, The Oxford English Dictionary dates the use of inadvertent to mean unintentional to 1742— and the American Heritage Dictionary says it still means that. If  is meant—with its connotation of culpability—then the word negligent should be used. The term inadvertence, by itself, does not convey that meaning to me, or to most people.
Her Daughter, Her Doctor
Authors: Maya Khankhoje
Journal: JAMA (1991)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Lipoprotein(a) in cirrhosis.
Authors: G. Utermann, H. G. Kraft
Journal: BMJ (1992)

Nursing time must be allowed for cleaning and disinfecting sigmoidoscopes during a list, and more than one sigmoidoscope may be required.Nursing time is required for correctly maintaining sigmoidoscopes and disinfection equipment weekly to keep all equipment in good condition and prevent cross infection.Sigmoidoscopy can be performed by general practitioners, but they must recognise that it is costly with important health and safety aspects.
Improved Prosthesis for The Aged Amputee
Authors: Homer L. Nelms
Journal: JAMA (1967)

To the Editor:—  The aged amputee must contend with feebleness and loss of ability to maintain balance. These account for many of the failures to provide these patients with satisfactory ambulation. While I was a patient in a rehabilitation center in a nearby city, I suggested to my bracemaker, William Bradley, the idea of a knee crutch. This he subsequently incorporated into an ordinary walker (Fig 1 and 2). This is primarily for the amputee who cannot be fitted with an artificial leg or who cannot use crutches satisfactorily. Feebleness is minimized and balance maintained with this type of prosthesis.
Genetic Metabolic Diseases: Early Diagnosis and Prenatal Analysis
Authors: Allen Horwitz
Journal: JAMA (1981)

The number of inborn errors of metabolism for which biochemical analysis is available has been increasing at an accelerating rate. The development of diagnostic tests for these disorders has allowed early treatment for some patients and more accurate genetic counseling in most affected families. The application of these techniques to prenatal diagnosis has allowed the prevention of many cases and has the potential to limit morbidity, including mental retardation. This monograph is an excellent attempt to summarize about 60 such metabolic disorders.  The text of this book contains a concise section on the extent of genetic metabolic disease and its role in infant mortality and morbidity. The individual diseases discussed are well summarized, both from the clinicopathological and biochemical-genetic viewpoints. The various sections are extremely well referenced, including recent developments within the limits of publication times.  A major part of this book is devoted to the methods of prenatal analysis
Suppression of anti-DNA antibody synthesis in vitro by a cross-reactive antiidiotypic antibody.
Authors: A Epstein, M Greenberg, B Diamond, A I Grayzel
Journal: Journal of Clinical Investigation (1987)

An understanding of the regulatory mechanisms that govern the humoral immune response will be facilitated by the availability of techniques for the measurement of specific antibody production in vitro. We have developed an enzyme-linked immunosorbent assay system for the measurement of in vitro anti-DNA antibody production by peripheral blood mononuclear cells (PBMC) from patients with systemic lupus erythematosus. Using this technique, the PBMC from 74% of serologically active SLE patients produced levels of anti-DNA antibodies that were greater than 2 SD above the mean of 18 +/- 9 IU/ml for normal subjects. Furthermore, the addition of 3I, a monoclonal anti-idiotypic antibody that recognizes a cross-reactive determinant on anti-DNA antibodies, was shown to specifically inhibit anti-DNA production in vitro.
Age Limits of Cytology For Cervical Cancer
Authors: Sam A. Nixon
Journal: JAMA (1968)

<h3>To the Editor:—</h3> In QUESTIONS AND ANSWERS (<b>203</b>:373, 1968), Christopher Tietze, MD, states: "It is considered good medical practice that all women, with or without IUD's, have a cytological evaluation (Papanicolaou smear) at annual intervals." At what age does Dr. Tietze suggest the process of obtaining annual pap smears begin?
THE AMERICAN MEDICAL ASSOCIATION; ITS PAST, PRESENT AND FUTURE.
Authors: N. SENN
Journal: JAMA (1897)

TheAmerican Medical Associationwas born at the dawn of a great era in the history of medicine. Only a few years before its organization was effected anesthesia, which has robbed the operating room of its greatest terrors, came into general use and at once opened up new fields of usefulness for the surgeon. The new science of bacteriology, upon which is based our modern views regarding the etiology and prevention of disease, has been founded and firmly established since that time. The principles which govern the present treatment of wounds conceived by the immortal Lister and developed to the existing state of perfection by a host of his enthusiastic followers, have revolutionized the practice of surgery during the last quarter of a century. Normal and pathologic microscopic anatomy are recent acquisitions to our knowledge of living tissues in health and disease. Aseptic midwifery is the direct descendent of aseptic
Glomerular cell proliferation and PDGF expression precede glomerulosclerosis in the remnant kidney model
Authors: Jürgen Floege, Mark W. Burns, Charles E. Alpers, Ashio Yoshimura, Pamela Pritzl, Katherine Gordon, Ronald A. Seifert, Daniel F. Bowen-Pope, William G. Couser, Richard J. Johnson
Journal: Kidney International (1992)
Indirect Immunofluorescence Assays Can Readily Detect Antibodies to the Human Immunodeficiency Virus
Authors: Jay A. Levy
Journal: JAMA (1987)

<h3>To the Editor.—</h3> I recently read in<i>JAMA</i>the report<sup>1</sup>of a Consensus Development Conference that considered methods for antibody testing and virus detection in persons infected with the human immunodeficiency virus. I was surprised that the indirect immunofluorescence assay (IFA) was not given much attention as a procedure for detecting or confirming the presence of antibody to the human immunodeficiency virus. This method is commonly used for the detection of antibodies to many other infectious agents. In our laboratory and in several others throughout the country, the IFA has proved to be extremely sensitive and specific for the virus.<sup>2-7</sup>It is accurate using plasma and serum and it is unaffected by heat inactivation. It is easy and rapid to perform: the result can be obtained in 30 minutes. Moreover, when virus-infected cells are mixed with control cells, nonspecific staining can be readily detected.<sup>3</sup>This technique rarely
Journal Editors Act to Enhance Reporting of Public Health Hazards
Authors: Stuart L. Nightingale
Journal: JAMA (1999)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Acute Improvement in Global and Regional Left Ventricular Systolic Function After Percutaneous Heart Valve Implantation in Patients With Symptomatic Aortic Stenosis
Authors: Fabrice Bauer, Hélène Eltchaninoff, Christophe Tron, Pierre-François Lesault, Carla Agatiello, Deborah Nercolini, Geneviève Derumeaux, Alain Cribier
Journal: Circulation (2004)

The newly developed percutaneous heart valve (PHV) implantation technique decreases transaortic pressure gradient in patients with aortic stenosis. PHV replacement effects on left ventricular (LV) global and regional systolic function are currently unknown.Eight patients with severe aortic stenosis had 2D echocardiography at baseline and 24 hours after PHV implantation to evaluate changes in LV volume and LV ejection fraction. Regional function, ie, both peak systolic anterior and posterior wall tissue velocity, as well as strain and strain rate imaging, were measured by tissue Doppler imaging from a short-axis view. At 24 hours, a significant reduction in transaortic mean pressure gradient (from 46+/-15 to 8+/-3 mm Hg; P<0.0001) was accompanied by an increase in aortic valve area (from 0.59+/-0.11 to 1.69+/-0.11 cm2; P<0.0001). LV end-diastolic volume remained unchanged (102+/-36 to 101+/-12 mL; P=NS), whereas LV ejection fraction increased (48+/-18% to 57+/-12%; P<0.01). Improvement in posterior wall displacement (posterior wall tissue velocity increased from 2.2+/-0.5 to 4.4+/-1.0 cm/s(-1); P=0.0003) and deformation (strain rate imaging increased from 1.0+/-0.3 to 1.9+/-0.7 s(-1), P=0.009, and strain increased from 11+/-5% to 17+/-9%; P=0.02) were observed.Immediately after PHV replacement, improvement of LV global and regional systolic function was evidenced by tissue Doppler imaging.
Current Status and Challenges in Jcog Data Center (DC) And Operations Office (OPS)
Authors: K. Nakamura, H. Fukuda, T. Shibata, H. Kaba, A. Takashima, Y. Tomii, A. Murooka, H. Toshima, J. Abe, H. Katayama, F. Kunieda, A. Kimura, K. Kanato, J. Mizusawa, N. Yamashita, K. Takeda, N. Matsuura, Y. Takiguchi, E. Sakaida, I. Sekine, H. Minami, K. Tamura, Y. Fujiwara, T. Hirohashi, J. Hashimoto, S. Yamaji, H. Uchida, S. Mori, X. Shi, S. Kameo, H. Aono, K. Aogi, Y. Ando, K. Yonemori, T. Shimizu, I. Okamoto, T. Kurata, Y. Fujisaka, J. Tsurutani, M. Nomura, T. Minami, K. Sakaguchi, R. Ohnishi, J. Chang, Y. Hase, K. Nakagawa, S. Yamamoto, S. Saji, F. Sato, T. Kinoshita, A. Tomita, S. Obi, S. Sato, T. Sato, T. Kawai, M. Kanda, T. Okusaka, A.-L. Cheng, M. Kudo, Y. Hirohashi, T. Torigoe, R. Morita, S. Nishizawa, A. Takahashi, S. Inoda, I. Hara, N. Sato, Y. Daigo, H. Yamaue, M. Miyazawa, N. Mizuno, A. Fukutomi, H. Ishii, S. Ohkawa, M. Furukawa, H. Maguchi, M. Ikeda, K. Nishio, Y. Ohashi, T. Tsunoda, H. Sugiyama, Masanori Noguchi, Shigetaka Suekane, Fukuko Moriya, Tetsuro Sasada, Akira Yamada, Kyogo Itoh, K. Suzuki, E. Baba, H. Kusaba, S. Takaishi, K. Akashi, T. Takano, T. Nakajima, N. Yamamoto, U. Tateishi, Y. Yamada, H. Iwata, T. Kuwata, K. Yamaguchi, A. Ooki, T. Yamada, H. Hara, M. Asayama, M. Tada, Y. Hamamoto, S. Funakoshi, H. Higuchi, H. Takaishi, T. Hibi, D. Maruyama, K. Tobinai, T. Nishida, S. Yano, M. Soda, H. Mano, T. Mukohara, T. Morita, T. Akechi, M. Maruguchi, M. Takahashi, T. Takayama, Y. Yatabe, P. A. Jänne, T. Sasaki, Y. Ohsaki, J. Pasi, Y. Aoki, S. Nishiuma, T. Kikkawa, M. Tahara
Journal: Annals of Oncology (2012)
Total central retinal artery occlusion successfully treated.
Authors: M. A. Nanjiani
Journal: BMJ (1966)

The leucocytosis and recurrent fever were misleading in suggesting a possible chronic infection.It is noteworthy that Campbell (1964) has suggested that a familial disease described by himself and Clifton (1950), thought to be toxoplasmosis and showing features such as chronic rash, leucocytosis, fever, pes cavus, nerve deafness, and choroido-retinitis, might in fact be another example of familial amyloidosis.Though our patient was born on the border of Derbyshire, all attempts to trace his relatives and any connexion with the Derbyshire family described by Muckle and Wells have failed.Despite this, we believe that the patient was an example of hereditary amyloid nephropathy.
A 46 year old man with carcinoma of unknown primary site
Authors: E. Liniker, S. Al-Jilaihawi, D. Propper, S. Slater, S. Pacey
Journal: BMJ (2012)

A 46 year old white man presented via the general medical on-call team with hypotensive collapse and melaena. Emergency oesophagogastroduodenoscopy after initial resuscitation showed bleeding duodenal ulcers that were amenable to endoscopic injection. On subsequent questioning by the admitting doctor, he reported gradually increasing abdominal girth, weight loss, and intermittent abdominal pain over the past two years. Systematic review yielded no further symptoms. His medical history was unremarkable and the only drug that he currently took was paracetamol. He smoked 15 cigarettes a day (20 pack years) and had no history of excess alcohol use.

Positive findings on examination were nodular hepatomegaly (2 cm below the costal margin) and a firm fixed 2 cm nodule at the umbilicus. He had no signs of chronic liver disease, and external genitalia and digital rectal examination were normal. There was no palpable lymphadenopathy and the remainder of the physical examination (including comprehensive skin examination for melanoma) was normal.

Computed tomography showed widespread liver omental and splenic deposits, consistent with metastases, and a 2 cm umbilical nodule. The primary source of the metastatic disease was not apparent.

Percutaneous biopsy of the umbilical nodule was performed. The provisional histology report confirmed that it was malignant and the patient was referred for an oncology opinion.



### 1 What further investigations are needed?

#### Short answer

Detailed histological examination of the tumour biopsy should be requested and the patient’s fitness for chemotherapy assessed. …
NONTRAUMATIC DISLOCATIONS OF THE ATLANTO-AXIAL JOINT
Authors: E. J. BERKHEISER
Journal: JAMA (1931)

Recently we have observed several cases of dislocation of the atlanto-axial articulation which were not associated with trauma but resulted as a complication of acute infectious diseases.  With the development of the roentgen ray, cases of traumatic dislocation of this joint have been diagnosed more frequently. Several of the cases, which have been described in the literature, had no evidence of injury to the spinal cord, but most of them were associated with fractures. The injury together with its mechanism of production and the roentgenographic appearances have been thoroughly described in the literature.  Many cases of dislocation have been noted which are the result of destructive diseases, such as tuberculosis and syphilis, but we were unable to find any reported cases of simple dislocation without associated trauma or destruction of bone.  The cases included in this report were dislocations at the atlanto-axial articulation which were direct complications of upper respiratory
To Its Knowledge
Authors: G. G. Liddle
Journal: JAMA (1966)

the Editor:—  I am continually puzzled by the phrase,  my knowledge. Is it a lazy writer's way of saying, According to my knowledge? I have before me an article which reads, To my knowledge, this is the first case of this combination of diseases in an individual reported in the literature. Leaving aside the graceless question of where such a report would be found except in the literature, may I infer that the writer's encyclopedic  of medicine is a reasonable guarantee of the truth of his statement? Or does he imply that he has spent weeks examining all the indexes of medicine, from which study he is now certain that this is a previously unrecorded experience? Can you enlighten me? Sometimes it seems to me that  my knowledge means exactly nothing. The phrase is usually followed by a statement, for which no support is offered. It
CLEANSING TREATMENT OF CHRONIC SUPPURATION OF THE MIDDLE EAR.
Authors: W. SOHIER BRYANT
Journal: JAMA (1907)

During an experience of twenty years' duration I have found that chronic suppuration of the middle ear will yield to cleansing treatment in the majority of cases, whether they be acute, chronic or perennial in type. In this statement I wish also to include those cases in which the infected area is spreading and those with acute exacerbation, both of which conditions are rightly considered very dangerous. The exceptions that do not yield comprise those cases in which the caries present is extensive enough to require more than a reasonable time for removal by natural processes; those in which there is an active osteitis; those in which the sepsis has spread to parts outside the bone; those in which the inflammation is due to some special form of infection, such as tuberculosis or syphilis, or, finally, cases in which vital parts are involved and demand immediate operation. All other cases
153 HIGHLY EFFICIENT DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS TO FUNCTIONAL HEPATOCYTES REQUIRES ACTIVIN A AND WNT3A SIGNALLING
Authors: D. Hay, J. Fletcher, C. Payne, J. Terrace, R. Gallagher, J. Black, A. Pryde, C. Filippi, S. Forbes, K. Samuel, J. Ross, J. Iredale, P. Newsome
Journal: Journal of Hepatology (2008)
Anatomical basis of P wave duration dispersion for the prediction of the development of atrial fibrillation after cardiac surgery
Authors: Takahisa Yamada, Tsuyoshi Shimonagata, Naoyuki Misaki, Mitsutoshi Asai, Nobuhiko Makino, Hidetaka Kioka, Shunsuke Tamaki, Masatake Fukunami
Journal: Journal of the American College of Cardiology (2003)
TEST OF GLOMERULAR EFFICIENCY
Authors: Geza Schinagel
Journal: JAMA (1935)

To the Editor:—  Drs. Edward J. Stieglitz and Alva A. Knight in their preliminary report on Sodium Ferrocyanide as a Clinical Test of Glomerular Efficiency (The Journal, Dec. 8, 1934, p. 1760) gave no credit to the originators of this test when presenting a new procedure.  Erich Leschke presented it (Histochemische Untersuchungen uber die funktion der Niere und Leber, in theVerhandlungen der deutschen Kongresses fur innere Medizin, Wiesbaden, 1914, p. 635, with Bunge). The first time sodium ferrocyanide as a renal functional test was spoken about was by Biberfeld and Basler.  Alois Wolff in reviving this test (Die geschlossene, kavernose Nierentuberkulose, in theZeitschrift fur urologische Chirurgie6:364, 1921) came to the conclusion that if the kidney function is sufficiently impaired the ferrocyanide salts are still traceable when neither indigocarmine nor phenolsulphonphthalein are eliminated any more.