THE CHEMOPROPHYLAXIS OF INFECTION
Authors: LOUIS WEINSTEIN
Journal: Annals of Internal Medicine (1955)

Article1 August 1955THE CHEMOPROPHYLAXIS OF INFECTIONLOUIS WEINSTEIN, Ph.D., M.D., F.A.C.P.LOUIS WEINSTEIN, Ph.D., M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-43-2-287 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe effectiveness of the antimicrobial agents in eliminating certain organisms and in curing the diseases produced by them has led to their use for the prevention of specific infectious processes, or of infection in general. The results obtained when antibiotics have been employed for this purpose have been quite variable. In some instances chemoprophylaxis has been eminently successful, in others it has failed completely, while in still others no conclusion can be reached because of the inadequacies of the available data.Chemoprophylaxis has been used primarily for four purposes: (1) to protect healthy individuals, either singly or in groups, against...Bibliography1. Baldwin JS: Sulfadiazine prophylaxis in children and adolescents with inactive rheumatic fever, J. Pediat. 30: 284-288, 1947. CrossrefMedlineGoogle Scholar2. Cheever FS: Dysentery outbreak aboard naval vessels in San Pedro Bay, U. S. Nav. M. Bull. 46: 479-494, 1946. MedlineGoogle Scholar3. DearingHeilman WHFR: The effect of Aureomycin on the bacterial flora of the intestinal tract of man; a contribution to preoperative preparation, Proc. Staff Meet., Mayo Clin. 25: 87-102, 1950. MedlineGoogle Scholar4. 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