The Deadliest Catch: Fishing for HIV in New Waters
Authors: Christopher D. Pilcher, C. Bradley Hare
Journal: Annals of Internal Medicine (2008)

Editorials5 August 2008The Deadliest Catch: Fishing for HIV in New WatersChristopher D. Pilcher, MD and C. Bradley Hare, MDChristopher D. Pilcher, MDFrom San Francisco General Hospital, San Francisco, CA 94110.Search for more papers by this author and C. Bradley Hare, MDFrom San Francisco General Hospital, San Francisco, CA 94110.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-149-3-200808050-00011 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail In the absence of an effective HIV vaccine, case findings and treatments are the mainstay of HIV prevention. Effective treatments are available, but more than 25% of HIV-infected individuals in the United States may not know that they are infected (1). Perhaps as a result, the rate of HIV transmission in the United States seems to be holding steady (2, 3). Two years ago, the Centers for Disease Control and Prevention (CDC) responded by announcing a bold new strategy to curb HIV transmission: screening average-risk individuals in an attempt to bring more people with HIV infection into treatment and care. ...References1. Glynn M, Rhodes P. Estimated HIV prevalence in the United States at the end of 2003 [Abstract]. Presented at the National HIV Prevention Conference, Atlanta, Georgia, 12–15 June 2005. Google Scholar2. Centers for Disease Control and Prevention (CDC). Revised recommendations for HIV testing of adults, adolescents, and pregnant women in health-care settings. MMWR Recomm Rep. 2006;55:1-17; quiz CE1-4. [PMID: 16988643] Google Scholar3. Centers for Disease Control and Prevention (CDC). Trends in HIV/AIDS diagnoses—33 states, 2001-2004. MMWR Morb Mortal Wkly Rep. 2005;54:1149-53. [PMID: 16292247] MedlineGoogle Scholar4. Walensky RP, Arbelaez C, Reichmann WM, Walls RM, Katz JN, Block BL, et al. 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Nanoparticle-based biobarcode amplification assay (BCA) for sensitive and early detection of human immunodeficiency type 1 capsid (p24) antigen. J Acquir Immune Defic Syndr. 2007;46:231-7. [PMID: 17693896] CrossrefMedlineGoogle Scholar13. Curtis KA, Rudolph DL, Owen SM. Rapid detection of HIV-1 by reverse-transcription, loop-mediated isothermal amplification (RT-LAMP). J Virol Methods. 2008;:. [PMID: 18524393] CrossrefMedlineGoogle Scholar14. Gray RH, Makumbi F, Serwadda D, Lutalo T, Nalugoda F, Opendi P, et al. Limitations of rapid HIV-1 tests during screening for trials in Uganda: diagnostic test accuracy study. BMJ. 2007;335:188. [PMID: 17545184] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From San Francisco General Hospital, San Francisco, CA 94110.Disclosures: None disclosed.Corresponding Author: Christopher D. Pilcher, MD, HIV/AIDS Division, San Francisco General Hospital, 995 Potrero Avenue, Ward 84, Building 80, San Francisco, CA 94110; e-mail, [email protected]ucsf.edu.Current Author Addresses: Drs. Pilcher and Hare: HIV/AIDS Division, San Francisco General Hospital, 995 Potrero Avenue, Ward 84, Building 80, San Francisco, CA 94110. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoRevising Expectations from Rapid HIV Tests in the Emergency Department Rochelle P. Walensky , Christian Arbelaez , William M. Reichmann , Ron M. Walls , Jeffrey N. Katz , Brian L. Block , Matthew Dooley , Adam Hetland , Simeon Kimmel , Jessica D. Solomon , and Elena Losina Metrics Cited ByStreamlining HIV Testing for HIV Preexposure ProphylaxisPerformance of Rapid Point-of-Care and Laboratory Tests for Acute and Established HIV Infection in San FranciscoThe laboratory diagnosis of HIV infectionLiterature Review 5 August 2008Volume 149, Issue 3Page: 204-205KeywordsAlgorithmsAntibodiesHIVHIV infectionsHematologic testsInfectious diseasesMotivationPrevention, policy, and public health ePublished: 5 August 2008 Issue Published: 5 August 2008 CopyrightCopyright © 2008 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...