Agranulocytosis: Its Classification*†
Authors: STEWART R. ROBERTS
Journal: Annals of Internal Medicine (1931)

Article1 July 1931Agranulocytosis: Its ClassificationCases and Comments Illustrating the Granulopenic Trend from 8,000 Blood Counts in the SouthSTEWART R. ROBERTS, M.D., F.A.C.P., ROY R. KRACKE, M.D.STEWART R. ROBERTS, M.D., F.A.C.P.Search for more papers by this author, ROY R. KRACKE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-5-1-40 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThis new disease that we call agranulocytosis is an important addition to the list of dangerous diseases. A biologic condition exists in which the granulocytes are removed from the bone marrow and the blood stream. This is apparently a relatively new condition which emphasizes the necessity for blood examinations, and the fact that the granulocyte is apparently a biologic necessity for life, opens up a whole new world for research upon the blood. In no other condition is there so clearly an opportunity to study possible functions of these cells that have hitherto been unknown. A brief illustration is of...References1 ROBERTSKRACKE SRRR: Agranulocytosis: Report of a case. J. A. M. A., 95:780 (Sept. 13), 1930. CrossrefGoogle Scholar2 WEISKOTTEN HG: The normal span of the neutrophilic leukocyte. The action of benzol. Amer. Jour. Path., 32:183 (March), 1930. Google Scholar3 OPIE EL: Intracellular digestion. Physiol. Review, 2:552, 1922. CrossrefGoogle Scholar4 WELLS HG: Clinical Pathology. W. B. Saunders and Co., 1925, p. 200. Google Scholar5 ROBERTS MH: Personal communication to the authors. Google Scholar6 ZABORSKY J: Roseola infectilis. Pediatrics, 22:60, 1910. Roseola infantum. J. A. M. A., 61:1446, 1913. See also Lucas, W. P.: Pediatrics, Macmillan, 1927, pp. 833-34 and references pp. 840-41. Google Scholar7 CABOT R: Clinical Examination of Blood. Wm. Wood and Co., 5th ed., 1909, p. 106. Google Scholar8 PINEY A: Recent Advances in Hematology. Blakiston's Son and Co., 1930, pp. 130-131. Google Scholar9 CLOUGH PW: Diseases of the Blood. Harpers, 1929, p. 63. Google Scholar10 WELLMAN HE: White blood counts. Rhode Island Med. Jour., 14: 51-54, 1931. Google Scholar11 BUCK RW: Agranulocytosis associated with anal ulcer. J. A. M. A., 93:1468-1469, (Nov. 9), 1929. CrossrefGoogle Scholar12 OSGOODHASKINS EEHD: Laboratory Diagnosis, Blakiston's Son and Co., 1931, p. 170. Google Scholar13 HADEN RL: Clinical Laboratory Methods. C. V. Mosby Co., 1929, p. 97. Google Scholar14 GARRYBUTLER MEV: Physiologic leukocytosis. Amer. Jour. Phys., 90:355 (Oct.), 1929. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Atlanta, Georgia*From the Emory University Hospital, Atlanta, Georgia.†Read at the Baltimore Meeting of the American College of Physicians, March 27, 1931. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byA son's book on his father's fatherGranulocyte StorageChronic Idiopathic NeutropeniaDEPRESSIVE INFLUENCES ON LEUKOCYTIC NUMBERSChronic hypoplastic neutropeniaGranulocytopenia in ChildrenAdenylic acid in the treatment of agranulocytosis and mucous membrane lesions “Some biochemical aspects of leukopenia”Erbpathologie des Blutes und der blutbildenden OrganeReport on a Case of Fulminating Idiopathic Agranulocytic Angina of Aplastic TypeTHE THERAPEUTIC ACTION OF THE NUCLEOTIDES; THE TREATMENT OF THE WHOLE BLOOD PICTURE WITH FERROUS ADENYLATE*SIMON L. RUSKIN, M.D., ELIHU KATZ, M.D.Agranulocytic anginaFURTHER STUDIES ON GRANULOPENIA WITH A REPORT OF TWELVE CASES*STEWART R. ROBERTS, F.A.C.P., ROY R. KRACKEThe Clinical Significance of Leucopenia with Special Reference to Idiopathic NeutropeniaSTACY R. METTIER, M.D., F.A.C.P., HARVEY T. OLSAN, M.D.Toxic Granulocytopenia, Purpura Hemorrhagica and Aplastic Anemia Following the Arsphenamines*†ADOLPH B. LOVEMAN, A.B., M.D. 1 July 1931Volume 5, Issue 1Page: 40-51KeywordsBiologicsBloodBone marrowCellsGranulocytesRivers Issue Published: 1 July 1931 PDF downloadLoading ...