tbuckley/cabot-search huggingface dataset:
PYOURETER SEVENTEEN YEARS AFTER NEPHRECTOMY
Authors: Selvan Davison
Journal: JAMA (1942)

The occurrence of pyoureter many years after nephrectomy without complete removal of the corresponding ureter is not common. In the case here presented the clinical picture caused by pyoureter was characterized mainly by obscure fever of six weeks' duration. <h3>REPORT OF CASE</h3><h3>History.—</h3> R. W., a woman aged 53 born in Russia had had rheumatic fever in childhood. A right mastoidectomy was performed thirty years before the present admission. An appendectomy was done five years later, followed in two weeks by a right ureterolithotomy. Eight years later a right nephrectomy for calculus pyonephrosis was performed at another hospital. For many years, until four years ago, the patient had attacks of cramping pain in the right upper quadrant of the abdomen brought on by food and relieved instantly by licorice powders. Eight years before this admission she was told that she had gallstones but refused operation. During the last seventeen
Points from Letters: Item-of-Service Payments
Authors: A. J. Reeves
Journal: BMJ (1967)

MEDICALJOUNALIt is proposed to reduce the size of the the C.C. and S. Committee from 96 to 82, which reduction includes the abolition of the 11 special group seats which provide direct representation for 5,378 consultants in specialties other than general surgery, general medicine, obstetrics, and gynaecology.It is doubtful whether a committee of 82 is any more efficient or manageable than one of 96, but it is undoubted that the proposed partial disenfranchisement of 5,378 consultants will be resented by those concerned.-Iam, etc.,
NEW METHOD OF SKIAGRAPHIC DIAGNOSIS FOR RENAL AND URETERAL SURGERY.
Authors: G. KOLISCHER
Journal: JAMA (1901)

Skiagraphy for medical purposes was especially ad- vanced and perfected in America.Calculous deposits were especially attractive for x-ray diagnosis.Mc- Arthur, Bevan, Leonard and others four years ago showed the necessity of skiagraphs in all suspected cases of renal stone.Our method, now to be described, will perfect the knowledge of the topography of the kidney and ureter, the location of calculi and aid in important differential diagnoses.A conservative and plastic sur- gery of kidneys and ureters has lately made such prog- Fig. 1.-Cadaver experiment.ress and achieved such good results\p=m-\werefer espe- cially to Fenger and McArthur cases\p=m-\thatthe absence of such diagnostic measures was the stimulus for our work.To a limited extent the different methods of collecting urine from each kidney and the cystoscopic observation of the ureteral openings has satisfied this desire.Skiagraphs frequently show the kidney-shaped shadow of the kidney while the representation of the ureters on the plate naturally failed on account of the delicate structures of these tubes.But, by the introduc- tion of a suitable axray absorbing material into these organs with a simultaneous skiagraph, results of the
Effects of Minute Doses of Gamma Globulin in Children with Active Allergic Manifestations
Authors: Bernard Redner
Journal: JAMA (1963)

Minute doses of gamma globulin, eg, 0.1 cc, were given intradermally to a group of allergic children, 4 to 13 years of age, in both an uncontrolled and a controlled series. It was found that this new modality was highly effective in controlling and preventing allergic manifestations resulting from or complicating upper respiratory infections. The gamma globulin used was derived from human placenta rather than from pooled human blood. An attempt was made to develop a working hypothesis for the mode of action of the gamma globulin in these allergic children.
Fluid Drinks After Laparotomy.
Authors: F. Byron Robinson.
Journal: JAMA (1894)

<h3>To the Editor:</h3> —The occasion of these remarks is the appearance of a nicely written little book on the " After-Treatment of Laparotomy" by Dr. Christopher Martin, the trusted assistant of Mr. Lawson Tait. Dr. Martin's book is just issued and as it is not published in this country, he kindly sent me one of the first numbers. In 1890, I was a pupil of Mr. Tait's for six months and at this time Dr. Martin had full charge of the after-treatment, as Mr. Tait seldom saw many of the patients after he had performed the operation. I then had ample opportunity to witness the after-treatment by<i>special permission</i>of Mr. Tait. Dr. Martin is a skilful surgeon and a keen observer of natural phenomena in the field of laparotomy. His little book is based on the after-treatment of 1,000 cases of abdominal section. He is possessed of independence sufficient to
Exposure to methyl tert-butyl ether and benzene among service station attendants and operators.
Authors: R Hartle
Journal: Environmental Health Perspectives (1993)

Concerns for atmospheric pollution from auto exhaust have led to the blending of "oxygenates" with motor fuels. The most common oxygenate, methyl tert-butyl ether (MTBE) is currently required within several metropolitan areas (Denver and Phoenix) in the range of 12% of the motor fuel. Amendments to the Clean Air Act may expand this requirement to as many as 44 other areas of the United States in the near future. In consideration of the magnitude of potential uncontrolled exposures from its extensive use and a related concern involving the potential influence of MTBE blending on exposures to other constituents of gasoline (particularly benzene), an evaluation of exposures among service station attendants and operators was undertaken at the request, and in cooperation with, the American Petroleum Institute during the latter part of 1990. For application of the survey results to a broad audience, three categories or types of service stations were identified with regard to MTBE use and exposure potential: a) service stations that do not use MTBE or use it only as an octane enhancer, b) service stations with seasonal requirements to use 12-15% MTBE (the Denver, Colorado, and Phoenix, Arizona, metropolitan areas), and c) service stations equipped with stage II (active) vapor recovery systems (several coastal areas, most notably Southern California). At the two sampled service stations that use only minimal amounts of MTBE (less than 1%), only 1 of 32 personal breathing zone (PBZ) samples from attendants was above the analytical limit of detection, reported at 0.16 ppm. The geometric mean concentration of benzene among this same population (n = 32) was 0.04 ppm.(ABSTRACT TRUNCATED AT 250 WORDS)
PREVALENCE OF HEART FAILURE BY CAUSE IN 21 REGIONS: GLOBAL BURDEN OF DISEASES, INJURIES AND RISK FACTORS – 2010 STUDY
Authors: Mohammad H. Forouzanfar, Andrew Moran, David Phillips, George Mensah, Majid Ezzati, Mohsen Naghavi, Christopher JL Murray
Journal: Journal of the American College of Cardiology (2013)
Tuberculous Arthritis—Unexpected Extrapulmonary Tuberculosis Detected by FDG PET/CT
Authors: Jui-Hsing Wang, Chih-Yu Chi, Kuo-Hsi Lin, Mao-Wang Ho, Chia-Hung Kao
Journal: Clinical Nuclear Medicine (2013)

FDG PET/CT imaging has been used in various medical fields, including neoplastic and infectious diseases, for a long time. We reported a 62-year-old man with fever, chronic cough, arthralgia of the left side of the hip, and body weight loss. Chest radiograph showed increased infiltration in both upper lungs, and the acid-fast stain of sputum was positive. Whole-body PET/CT scan revealed a lesion with intense FDG uptake in the joint of the side left of the hip. Osteoarthritis of the hip was initially impressed by an orthopedist. However, tuberculous arthritis was subsequently confirmed by deep pus culture.
Effects of alpha-human atrial natriuretic peptide on the interrelationship of arterial pressure, aortic nerve activity, and aortic diameter.
Authors: Y Hirooka, A Takeshita, T Imaizumi, N Nakamura, H Tomoike, M Nakamura
Journal: Circulation Research (1988)

A previous study has suggested that atrial natriuretic peptide (ANP) alters arterial baroreflex control of lumbar and renal sympathetic nerve activity. To explore these mechanisms, we examined the interrelationship of arterial pressure, afferent aortic nerve activity, and aortic diameter in rabbits anesthetized with alpha-chloralose before and after sinoaortic denervation and bilateral vagotomy. Arterial pressure was decreased in stepwise fashion by intravenous infusion of alpha-human ANP (alpha-hANP, 0.1-1.0 microgram/kg/min) or sodium nitroprusside (SNP, 1-5 micrograms/kg/min). Both in rabbits with intact baroreceptors and in those with baroreceptors denervated, aortic nerve activity and the aortic diameter decreased during hypotension caused by the infusion of SNP but remained unchanged during hypotension caused by the infusion of alpha-hANP. In addition, we examined the effects of alpha-hANP and SNP on the responses of the aortic diameter and aortic nerve activity to rapid changes in arterial pressure caused by intravenous phenylephrine or nitroglycerin. Changes in aortic nerve activity and the aortic diameter in response to rapid changes in arterial pressure caused by phenylephrine or nitroglycerin were not different between the infusion of alpha-hANP and SNP. These results suggest that aortic nerve activity remains unchanged despite hypotension during the infusion of alpha-hANP, because alpha-hANP dilates the aorta. Since the aortic diameter increases, strain of aortic baroreceptors does not decrease. A second suggestion is that alpha-hANP does not alter aortic baroreceptor responses to changes in arterial pressure caused by phenylephrine or nitroglycerin.
hTERT, the catalytic component of telomerase, is downregulated in the haematopoietic stem cells of patients with chronic myeloid leukaemia
Authors: L J Campbell, C Fidler, H Eagleton, A Peniket, R Kusec, S Gal, T J Littlewood, J S Wainscoat, J Boultwood
Journal: Leukemia (2006)
Antagonism of quinidine's electrophysiologic effects by epinephrine in patients with ventricular tachycardia
Authors: Fred Morady, William H. Kou, Alan H. Kadish, Steven D. Nelson, Lauri K. Toivonen, Jeffrey A. Kushner, Stephen Schmaltz, Michael de Buitleir
Journal: Journal of the American College of Cardiology (1988)
EFFICACY AND SAFETY OF 4F NEW TRANSRADIAL DIAGNOSTIC CATHETER; RM AND CR CATHETER FOR ENGAGING BOTH LEFT AND RIGHT CORONARY ARTERIES
Authors: Seung Woon Rha, Ji Young Park, Kanhaiya L. Poddar, Sureshkumar Ramasamy, Lin Wang, Byoung Geol Choi, Ji Bak Kim, Seung Yong Shin, Cheol Ung Choi, Hong Euy Lim, Jin Won Kim, Eung Ju Kim, Chang Gyu Park, Hong Seog Seo, Dong Joo Oh
Journal: Journal of the American College of Cardiology (2010)
Some Aspects of Myogenesis in Vitro
Authors: Ludwig W. Eichna, IRWIN R. KONIGSBERG
Journal: Circulation (1961)

Suspensions of embryonic chick leg muscle cells have been employed to establish replicate monolayer cultures. Such cultures grow rapidly to form a confluent layer of cells. Despite culture conditions generally assumed to be "dedifferentiative," a high degree of differentiation is attained in terms of the development of cross-striated myofibrils and contractility. To evaluate the possible role of in situ nuclear replication in the development of multinuclearity in muscle cells, an inhibitor of deoxyribonucleic acid (DNA) synthesis, methyl-bis (betachloroethylamine) (nitrogen mustard), was employed. Treatment with nitrogen mustard at concentration levels that profoundly inhibit DNA synthesis does not block the formation of multinuclear cells. On the basis of the pattern of nuclear enlargement after nitrogen mustard treatment, the cytologic picture of treated cultures is interpreted as indicating that the nuclei of only mononucleated cells are normally capable of proliferation. An absence of proliferative activity in the nuclei of multinuclear cell suggests that myoblast proliferation is self-limiting in this system and may explain, in part, the high degree of differentiation attained in monolayer culture.
The mysterious "urethral syndrome"
Authors: R. K Ditchburn
Journal: BMJ (1991)

Bleeding peptic ulcers SIR,-Professor Stephen Bown is correct to remark on the recent advances in endoscopic treatment of bleeding peptic ulcers.With the emerging evidence of the efficacy of endoscopic techniques, and with an aging population, who tolerate laparotomv badly, these techniques should be more widely available.Professor Bown discusses the evidence of their efficacy in a traditional narrative manner, and I am confident that his conclusions are correct.He has not, however, explored the results of three relevant meta-analyses.24Two of these studies were reviewed at a workshop on meta-analysis in gastrointestinal haemorrhage held in Newcastle, New South Wales, in September last year.'This was a satellite meeting of the World Congress of Gastroenterology.The table summarises the results presented at the workshop.Several conclusions can be drawn.Firstly, evidence of benefit seems to be greatest in the case of laser treatments, with both meta-
Follow surgical checklists and take time out, especially in a crisis
Authors: D. N. Hunter, S. J. Finney
Journal: BMJ (2011)

In June 2008 the World Health Organization launched its second global patient safety challenge, “Safe surgery saves lives” ( BMJ 2008;337:a2370, doi:10.1136/bmj.a2370). This three part surgical safety checklist aimed to reduce the incidence of wrong site surgeries and increase the surgical team’s preparedness for anaesthetic and surgical complications. 

The following January the UK National Patient Safety Agency issued a patient safety alert that required hospitals to institute this three stage checklist for all surgical patients by February 2010: sign in (before anaesthesia); time out (before incision); sign out (after the operation). Many will remember the hilarity and amazement expressed on Radio 4’s Today programme on the morning of the agency’s announcement that such a simple procedure was not already in use to ensure that the right operation was taking place on the right patient.

Nearly two years later, however, many remain …
American and Soviet Teenagers and Nuclear War
Authors: John E. Mack
Journal: New England Journal of Medicine (1988)

IN a study that is a model of scientific collaboration between the United States and the Soviet Union, Eric Chivian and his Soviet and American colleagues in this issue of the Journal 1 provide a methodologically sophisticated comparison of the attitudes toward nuclear war and the future of teenagers in the U.S.S.R. with those of teenagers in the United States. The article stems from an international survey of adolescent attitudes toward these and other matters. Except for more realism in the American sample about the likelihood of surviving a large-scale nuclear war — probably the result of public education on this . . .
The Treatment of Stingray Injuries
Authors: Jorge Hartmann
Journal: JAMA (1966)

ABSTRACT To the Editor:— In tropical climates stingray wounds may not heal for months (195:708, 1966), leaving bad scars. Since 1940 a treatment has been used which yields rapid healing without unbearable pains. There is no scarring of significance and a minimum incapacitation during recovery.The sting of the stingray is a bone, like a double-toothed saw, which lies in a small canal over the tail of the fish. This canal contains glands which secrete a sticky liquid, which is strongly alkaline and is highly destructive to soft tissues.The treatment I have followed consists of immersing the affected member in a warm solution of lactic acid in water, 0.5% to 1.0% depending upon the size of the wounds. This is continued for three to five days. Secondary infection is prevented by the administration of antibiotics.Under this regimen analgesics are needed in minimal amount, if at all. In four
TCT- 474 Triple vs. Dual Antithrombotic Therapy In Patients With Atrial Fibrillation And Acute Coronary Syndromes: The AVIATOR Registry
Authors: Georgios Christodoulidis, Marco G. Mennuni, Samantha Sartori, usman baber, George Dangas, Samin Sharma, Annapoorna Kini, Corrado Tamburino, Alaide Chieffo, Antonio Colombo, Patrizia Presbitero, Roxana Mehran
Journal: Journal of the American College of Cardiology (2014)
HDLs: Heart Boon but Cancer Signal?
Authors: K. Smigel
Journal: JNCI Journal of the National Cancer Institute (1990)

HDLs: Heart Boon but Cancer Signal? Get access Kara Smigel Kara Smigel Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 82, Issue 6, 21 March 1990, Page 451, https://doi.org/10.1093/jnci/82.6.451-a Published: 21 March 1990
Comorbidity, Disability, and Geriatric Syndromes in Elderly Cancer Patients Receiving Home Health Care
Authors: Siran M. Koroukian, Patrick Murray, Elizabeth Madigan
Journal: Journal of Clinical Oncology (2006)

To assess the prevalence of comorbidity, disability, and geriatric syndromes, or a combination thereof, in elders with cancer receiving home health care (HHC).Using the Ohio Cancer Incidence Surveillance System, we identified Ohio residents 65 years of age or older who were diagnosed with incident breast (n = 952), prostate (n = 324), or colorectal cancer (n = 1,276) during the 28-month study period, August 1999 through November 2001. We used the Outcome and Assessment Information Set, a database compiling comprehensive assessment forms completed for all HHC patients, to group individuals in independent and overlapping categories of comorbidity, disability, and geriatric syndromes on the basis of the patients' clinical condition 14 days before the date of the assessment.The proportion with no comorbidity, disability, or geriatric syndromes was 26.4% in breast cancer patients, 12.0% in prostate cancer patients, and 14.0% in colorectal cancer patients. The proportion of patients presenting all three entities at once was 11.7%, 24.7%, and 15.7%, respectively, in three cancer sites. As expected, the proportion of patients with no comorbidity, disability, or geriatric syndromes declined gradually with increasing age, and that of patients with all three entities was highest among patients 85 years or older.The proposed taxonomy will help us gain a more nuanced understanding of older cancer patients' clinical presentation and may lead to a more accurate identification of older patients who might benefit from standard cancer treatment, and those who might experience adverse outcomes.
Progress in Standard of Care Therapy and Modest Survival Benefits in the Treatment of Non-small Cell Lung Cancer Patients in the Netherlands in the Last 20 Years
Authors: Miep A. van der Drift, Henrike E. Karim-Kos, Sabine Siesling, Harry J.M. Groen, Michel W.J.M. Wouters, Jan-Willem Coebergh, Esther de Vries, Maryska L.G. Janssen-Heijnen
Journal: Journal of Thoracic Oncology (2011)
Permanent impairment of renal function after methicillin nephropathy.
Authors: H A Jensen, A B Halveg, K I Saunamaki
Journal: BMJ (1971)

A favourable prognosis has usually been given in cases of nephropathy due to methicillin, but until now there has been no report of the findings in a repeat renal biopsy.We report a case of methicillin nephropathy in which renal biopsy and in- vestigations two years later showed evidence of residual renal damage.
Sources of Mercury Exposure for U.S. Seafood Consumers: Implications for Policy
Authors: Noelle E. Selin, Elsie M. Sunderland, Christopher D. Knightes, Robert P. Mason
Journal: Environmental Health Perspectives (2009)

Recent policies attempting to reduce adverse effects of methylmercury exposure from fish consumption in the United States have targeted reductions in anthropogenic emissions from U.S. sources.To analyze the prospects for future North American and international emissions controls, we assessed the potential contributions of anthropogenic, historical, and natural mercury to exposure trajectories in the U.S. population over a 40-year time horizon.We used models that simulate global atmospheric chemistry (GEOS-Chem); the fate, transport, and bioaccumulation of mercury in four types of freshwater ecosystems; and mercury cycling among different ocean basins. We considered effects on mercury exposures in the U.S. population based on dietary survey information and consumption data from the sale of commercial market fish.Although North American emissions controls may reduce mercury exposure by up to 50% for certain highly exposed groups such as indigenous peoples in the Northeast, the potential effects of emissions controls on populations consuming marine fish from the commercial market are less certain because of limited measurements.Despite uncertainties in the exposure pathway, results indicate that a combination of North American and international emissions controls with adaptation strategies is necessary to manage methylmercury risks across various demographic groups in the United States.
Public Funds and the Injured Motorcyclist
Authors: Bernard R. Bach
Journal: JAMA (1986)

To the Editor.—  The article by Bray et al 1 is timely in this era of increasing medical and socioeconomic accountability. We also have been concerned about the costs of hospitalized motorcyclists, and we conducted our own retrospective study of patients admitted to the Massachusetts General Hospital, a level 1 trauma center, over a one-year period.  In our study, Financial Charges of Hospitalized Motorcyclists, 2 we evaluated hospitalization charges and lengths and insurance and injury profiles. We found the following: (1) The mean charges for hospitalization of 47 patients was $15,114. This represented a twofold factor when compared with our entire hospitalized population. (2) The total hospital charge for this group was $700,000. (3) Our figures represented the tip of the iceberg, since these charges represent the initial hospital charges. (4) Forty-six percent of the patients were uninsured at the time of admission. (5) Uncollectable charges involved 16% of the
Sarcolipin is a newly identified regulator of muscle-based thermogenesis in mammals
Authors: Naresh C Bal, Santosh K Maurya, Danesh H Sopariwala, Sanjaya K Sahoo, Subash C Gupta, Sana A Shaikh, Meghna Pant, Leslie A Rowland, Eric Bombardier, Sanjeewa A Goonasekera, A Russell Tupling, Jeffery D Molkentin, Muthu Periasamy
Journal: Nature Medicine (2012)