Recent Advances Relative to Diabetes Mellitus
Authors: ROBERT H. WILLIAMS
Journal: Annals of Internal Medicine (1965)

Review1 September 1965Recent Advances Relative to Diabetes MellitusROBERT H. WILLIAMS, M.D., F.A.C.P.ROBERT H. WILLIAMS, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-63-3-512 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn most patients with diabetes mellitus, the primary fundamental defect has not been elucidated, but there is much to indicate that it is on a hereditary basis. Many individuals destined to develop the disease do not manifest hyperglycemia, glycosuria, and other classic features until many years after birth. Most individuals studied have been found to show various types of microvascular histological changes (1) before they manifest overt abnormalities in blood sugar. 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Author, Article, and Disclosure InformationAffiliations: From the Department of Medicine, the University of Washington, Seattle, Wash.Presented as the Alfred Stengel Memorial Lecture at the Golden Anniversary Session of the American College of Physicians, Chicago, Ill., March 24, 1965.Requests for reprints should be addressed to Robert H. Williams, M.D., Department of Medicine, University of Washington, Seattle, Wash. 98105. 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