Risk Factors for Deep Venous Thrombosis of the Upper Extremities
Authors: Deepti Pandita
Journal: Annals of Internal Medicine (1997)

Letters15 December 1997Risk Factors for Deep Venous Thrombosis of the Upper ExtremitiesDeepti Pandita, MD, Preston Steen, MD, and Anil Potti, MDDeepti Pandita, MDUniversity of North Dakota; Fargo, ND 58102Search for more papers by this author, Preston Steen, MDUniversity of North Dakota; Fargo, ND 58102Search for more papers by this author, and Anil Potti, MDUniversity of North Dakota; Fargo, ND 58102Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-127-12-199712150-00018 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:We read with interest the article by Martinelli and colleagues [1] on evaluating risk factors for deep venous thrombosis of the upper extremities. Although the authors claim to have tested their patients for all possible causes of thrombophilia, they did not mention a rare but important cause: factor XII deficiency.We admitted a 62-year-old white woman who presented with spontaneous deep venous thrombosis in the left axillary vein. Coagulation studies done before heparin therapy was started revealed an abnormal partial thromboplastin time of 114 seconds (the normal range at our laboratory is 25 to 40 seconds). Further ...References1. Martinelli I, Cattaneo M, Panzeri D, Taioli E, Mannucci M. Risk factors for deep venous thrombosis of the upper extremities. Ann Intern Med. 1997; 126:707-11. Google Scholar2. Winter M, Gallimore M, Jones DW. Should factor XII assay be included in thrombophilia screening? [Letter] Lancet. 1995; 346:52. Google Scholar3. Castaman G, Ruggeri M, Tosetto A, Missiaglia E, Rodeghiero F. Thrombosis in patients with heterozygous and homozygous factor XII deficiency is not explained by associated presence of factor V Leiden [Letter]. Thromb Haemost. 1996; 76:275. Google Scholar4. Halbmayer WM, Haufsofer A, Schon R, Mannhalter C, Strohmer E, Baumgarten K, et al. The prevalence of moderate and severe factor XII deficiency among the normal population: evaluation of the incidence of factor XII deficiency among 300 healthy blood donors. Thromb Haemost. 1994; 71:68-72. Google Scholar Author, Article, and Disclosure InformationAffiliations: University of North Dakota; Fargo, ND 58102 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byComparative incidence of thrombosis in reported cases of deficiencies of factors of the contact phase of blood coagulationDeep venous thrombosis and previous myocardial infarction in mild factor XII deficiency: a risk factor for both venous and arterial thrombosisLemierre’s Syndrome Complicating Bacterial Pharyngitis in a Patient With Undiagnosed Factor XII DeficiencyPrevalence of Common Mutations and Polymorphisms of the Genes of FII, FV, FVII, FXII, FXIII, MTHFR and ACE — Identified As Risk Factors for Venous and Arterial Thrombosis — in Germany and Different Ethnic Groups (Indians, Blacks) of Costa Rica 15 December 1997Volume 127, Issue 12Page: 1129KeywordsDeep vein thrombosisFemoral arteriesHeparinMedical risk factorsPartial thromboplastin timeResearch laboratoriesRisk managementThrombosisVeins Issue Published: 15 December 1997 Copyright & PermissionsCopyright © 1997 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...