Chronic Hiccups and Gastroesophageal Reflux Disease: The Acid Perfusion Test as a Provocative Maneuver
Authors: MICHAEL GLUCK
Journal: Annals of Internal Medicine (1986)

Brief Report1 August 1986Chronic Hiccups and Gastroesophageal Reflux Disease: The Acid Perfusion Test as a Provocative ManeuverMICHAEL GLUCK, M. D., CHARLES E. POPE II, M.D.MICHAEL GLUCK, M. D., CHARLES E. POPE II, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-105-2-219 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptHICCUPS (singultus) usually provoke a tolerant smile and the prompt application of home remedies. Any impersonation of an inebriated person is not complete without hiccups. However, in an immediate postoperative situation where such violent diaphragmatic contractions can disrupt suture lines, hiccups are not a laughing matter. Intractable hiccups take on a disturbing character to both sufferer and physician. Previous reviews of the topic (1-3) have listed many causes for intractable hiccups, and in all lists one finds "esophagitis and hiatal hernia." Yet, no studies clearly show that an irritated esophagus can produce chronic hiccups.We have recently treated an alcoholic...References1. KELLOGG E and MEYER W. HICCOUGH. Med Rec. 1935;142:441-4. Google Scholar2. SOUADJIAN J and CAIN J. Intractable hiccup: etiologic factors in 220 cases. Postgrad Med. 1968;43:72-7. CrossrefMedlineGoogle Scholar3. SAMUELS L. Hiccup. Can Med Assoc J. 1952;67:315-22. MedlineGoogle Scholar4. HOGAN W, VIEGAS DE ANDRADE S, and WINSHIP D. Ethanol-induced acute esophageal motor dysfunction. J Appl Physiol. 1972;32:755-60. CrossrefMedlineGoogle Scholar5. KAUFMAN S and KAYE M. Induction of gastro-oesophageal reflux by alcohol. Gut. 1978;19:336-8. CrossrefMedlineGoogle Scholar6. BAKER A and BAKER L eds. Clinical Neurology. New York: Harper & Row; 1983. Google Scholar7. MANSFIELD L, HAMEISTER H, SPAULDING H, SMITH N, and GLAB N. The role of the vagus nerve in airway narrowing caused by intraesophageal hydrochloric acid provocation and esophageal distention. Ann Allergy. 1981;47:431-4. MedlineGoogle Scholar8. DAVIS J. An experimental study of hiccup. Brain. 1970;93:851-72. CrossrefMedlineGoogle Scholar9. OSLER W ed. The Principles and Practice of Medicine. New York: Appleton; 1905:1034-5. Google Scholar10. GIGOT A and FLYNN P. Treatment of hiccups. JAMA. 1952;150:760-4. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: MICHAEL GLUCK, M. D.; CHARLES E. POPEII, M.D.Affiliations: Veterans Administration Medical Center University of Washington Seattle, Washington PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPersistent hiccups following thalamic hemorrhage: A case reportHiccups in neurocritical careChronic HiccupsTreatment of persistent hiccups after arthroplasty: effects of acupuncture at PC6, CV12 and ST36Hiccup: Mystery, Nature and TreatmentClinical Spectrum and Diagnosis of Gastroesophageal Refux DiseaseProtracted Hiccups due to Severe Erosive EsophagitisIntractable hiccups during stroke rehabilitationGASTROESOPHAGEAL REFLUX IN CHILDRENBehaviors Associated With Onset of Gastroesophageal Reflux Episodes in InfantsVagal Reflexes Referred from the Upper Aerodigestive Tract: An Infrequently Recognized Cause of Common Cardiorespiratory ResponsesEmmett T. Cunningham Jr., MD, PhD, MPH, William J. Ravich, MD, Bronwyn Jones, FRCP, Martin W. Donner, MDPremedication with metoclopramide decreases the frequency of methohexital induced hiccupHiccups and AchalasiaHoward Seeman, MD, Morris Traube, MDGastroesophageal refluxHiccups (Singultus): Review and approach to managementThe Spectrum of the Symptoms and Presentations of Gastroesophageal Reflux DiseaseComplications of Reflux Esophagitis and Their Medical ManagementGastroesophageal refluxHiccups and gastroesophageal reflux: Cause and effect?Gastroesophageal reflux and respiratory disease in childrenTrimethoprim-Sulfamethoxazole, Hiccups, and Esophageal UlcersDONALD SEIBERT, M.D., FIRAS AL-KAWAS, M.D.Case 3, 1986 1 August 1986Volume 105, Issue 2Page: 219-220KeywordsAlcoholicsEsophagusGastroesophageal reflux diseaseHernia ePublished: 1 December 2008 Issue Published: 1 August 1986 PDF downloadLoading ...