The Course of Non-A, Non-B Hepatitis Unrelated to Transfusion
Authors: David L. Thomas, Kenrad Nelson, Thomas C. Quinn
Journal: Annals of Internal Medicine (1994)

Letters15 January 1994The Course of Non-A, Non-B Hepatitis Unrelated to TransfusionDavid L. Thomas, MD, MPH, Kenrad Nelson, MD, and Thomas C. Quinn, MD, MscDavid L. Thomas, MD, MPHJohns Hopkins Medical Institutions; Balitmore, MD 21205National Institutes of Health; Bethesda, MD 20892Search for more papers by this author, Kenrad Nelson, MDJohns Hopkins Medical Institutions; Balitmore, MD 21205National Institutes of Health; Bethesda, MD 20892Search for more papers by this author, and Thomas C. Quinn, MD, MscJohns Hopkins Medical Institutions; Balitmore, MD 21205National Institutes of Health; Bethesda, MD 20892Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-120-2-199401150-00031 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:In describing the natural history of post-transfusion non-A, non-B hepatitis, 75% to 90% of which is due to the hepatitis C virus (HCV), Koretz and coworkers [1] raise an important issue regarding the long-term implications of HCV infections. They show that patients in their cohort of patients with transfusion-acquired HCV generally died of conditions unrelated to their HCV infections and that many of those with advanced liver disease resulting from HCV were asymptomatic. Seeff and coworkers [2] also reported that patients with post-transfusion non-A, non-B hepatitis did not have a greater mortality than did uninfected controls. These ...References1. Koretz RL, Abbey H, Coleman E, Gitnick G. Non-A, non-B post-transfusion hepatitis. Looking back in the second decade. Ann Intern Med. 1993; 119:110-5. Google Scholar2. Seeff LB, Buskell-Bales Z, Wright EC, Durako SJ, Alter HJ, Iber FL, et al. Long-term mortality after transfusion-associated non-A, non-B hepatitis. The National Heart, Lung, and Blood Institute Study Group. N Engl J Med. 1992; 327:1906-11. Google Scholar3. Kelen GD, Green GB, Purcell RH, Chan DW, Qaqish BF, Sivertson KT, et al. Hepatitis B and hepatitis C in emergency department patients. N Engl J Med. 1992; 326:1399-404. Google Scholar4. Kiyosawa K, Sodeyama T, Tanaka E, Gibo Y, Yoshizawa, Nakano Y, et al. Interrelationship of blood transfusion, non-A, non-B hepatitis and hepatocellular carcinoma: analysis by detection of antibody to hepatitis C virus. Hepatology. 1990; 12:671-5. Google Scholar5. Donahue JG, Munoz A, Ness PM, Brown DE Jr, Yawn DH, McAllister HA Jr, et al. The declining risk of post-transfusion hepatitis C virus infection. N Engl J Med. 1992; 327:369-73. Google Scholar Author, Article, and Disclosure InformationAffiliations: Johns Hopkins Medical Institutions; Balitmore, MD 21205National Institutes of Health; Bethesda, MD 20892 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byHepatitis C EpidemiologyMIXED CRYOGLOBULINEMIA SECONDARY TO HEPATITIS C VIRUS INFECTION 15 January 1994Volume 120, Issue 2Page: 171-172KeywordsHepatitisHepatitis AHepatitis C virusHepatocellular carcinomaInfectious diseasesInfectious hepatitisLiver diseasesMortalityPregnancySexually transmitted diseases Issue Published: 15 January 1994 Copyright & PermissionsCopyright © 1994 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...