Byssinosis: Causes and Practical Control
Authors: KAYE H. KILBURN
Journal: Annals of Internal Medicine (1984)

Editorials1 August 1984Byssinosis: Causes and Practical ControlKAYE H. KILBURN, M.D.KAYE H. KILBURN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-101-2-252 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAfter it was predicted that the respirable portion of cotton dust triggered tightness in the chest, cough, and shortness of breath in exposed textile workers, the prediction was confirmed and the dust effect shown quantitatively in textile mills in 1970 (1). Since then the nature and source of the agent (s) responsible have been investigated. Assays to determine response have ranged from leukocyte chemotaxis in vitro to panels of susceptible human subjects in model cardrooms. The final arbiter of the response must be the whole population of textile plant workers, as the experience with steaming cotton has shown (2). Candidates...References1. MERCHANTLUMSDENKILBURN JJK. Dose response studies in cotton textile workers. J Occup Med. 1973;15:222-30. MedlineGoogle Scholar2. MERCHANTLUMSDENKILBURN JJK. Intervention studies of cotton steaming to reduce biological effects of cotton dust. Br J Ind Med. 1974;31:261-74. MedlineGoogle Scholar3. DOUGLASDUNCAN JP. Characterisation of textile dust extracts: I. Histamine release in vitro. Br J Ind Med. 1984;41:64-9. MedlineGoogle Scholar4. PERNISVIGLIANICAVAGNA BEC. The role of bacterial endotoxins in occupational diseases caused by inhaling vegetable dusts. Br J Ind Med. 1961;81:120-9. Google Scholar5. CASTILLONALTSCHUL LA. Preparation of water-soluble combination products of gossypol and their toxicity for aquarium fish. Proc Soc Exp Biol Med. 1950;74:623-6. CrossrefMedlineGoogle Scholar6. WAKELYNSTIPANOVICBELL PRA. Identification of scopoletin in dried bract of the cotton plant. J Agric Food Chem. 1974;22:567-8. CrossrefMedlineGoogle Scholar7. HEDINTHOMPSONGUELDNER PAR. A survey of the volatile constituents of cotton lint and waste with regard to byssinosis. J Agric Food Chem. 1975;23:698-703. CrossrefMedlineGoogle Scholar8. WAKELYNGREENBLATTBROWNTRIPP PGDV. Chemical properties of cotton dust. Am Ind Hyg Assoc J. 1976;37:22-31. CrossrefMedlineGoogle Scholar9. JEFFSLYNN PD. Isolation and structure of 1-hydroxy-7-methoxy-4-isopropyl-1,6-dimethyl-2(IH)-naphthalenone from cotton. J Org Chem. 1975;40:2958-60. CrossrefGoogle Scholar10. KILBURNLYNNTRESMCKENZIE KWLW. Leukocyte recruitment through airway walls by condensed vegetable tannins and quercetin. Lab Invest. 1973;28:55-9. MedlineGoogle Scholar11. CASTELLANOLENCHOCKHANKINSON RSJ. Acute bronchoconstriction induced by cotton dust: dose-related responses to endotoxin and other dust factors. Ann Intern Med. 1984;101:157-63. LinkGoogle Scholar12. RYLANDERHAGLIND RP. Relation between FEV1 changes over workshift and cotton/endotoxin levels. In: WAKELYN PJ, JACOBS RR, eds. Proceedings of the 7th Cotton Dust Research Conference. Memphis: National Cotton Council; 1983:17-8. Google Scholar13. BUCKSCHACHTER ME. Partial composition of a low molecular weight cotton bract extract which induces airway constriction in humans. In: WAKELYN PJ, JACOBS RR, eds. Proceedings of the 6th Cotton Dust Research Conference. Memphis: National Cotton Council; 1982:19-23. Google Scholar14. MERCHANTHALPRINHUDSON JGA. Evaluation before and after exposure—the pattern of physiological response to cotton dust. Ann NY Acad Sci. 1974;221:38-43. CrossrefMedlineGoogle Scholar15. LYNNPHILLIPSLYNN DNW. Accumulation of cytotoxins in human lung. In: WAKELYN PJ, JACOBS RR, eds. Proceedings of the 8th Cotton Dust Research Conference. Atlanta: National Cotton Council; 1984:96-9. Google Scholar16. BERRYMCKERROWMOLYNEUXROSSITERTOMBLESON GCMCJ. A study of the acute and chronic changes in ventilatory capacity of workers in Lancashire cotton mills. Br J Ind Med. 1973;30:25-36. MedlineGoogle Scholar17. IMBUSSUH HM. Byssinosis, a study of 10,133 textile workers. Arch Environ Health. 1976;26:183-91. CrossrefGoogle Scholar18. Occupational exposure to cotton dust: part 1910 and 1928. Fed Reg. 1978;43:27350-462. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByByssinosis in Hemp Mill WorkersHypersensitivity pneumonitisCotton dust contains proteolytic and elastolytic enzymes not inhibited by alpha-1-proteinase inhibitor 1 August 1984Volume 101, Issue 2Page: 252-254KeywordsChemotaxisDustDyspneaThorax Issue Published: 1 August 1984 PDF DownloadLoading ...