Airway Adrenaline in Patients with Severe Cardiac Disease
Authors: Konstantinos Raymondos, Bernhard Panning, Siegfried Piepenbrock
Journal: Annals of Internal Medicine (2001)

Letters1 May 2001Airway Adrenaline in Patients with Severe Cardiac DiseaseKonstantinos Raymondos, MD, Bernhard Panning, MD, and Siegfried Piepenbrock, MDKonstantinos Raymondos, MDMedizinische Hochschule Hannover; 30625 Hannover, Germany (Raymondos, Panning, Piepenbrock)Search for more papers by this author, Bernhard Panning, MDMedizinische Hochschule Hannover; 30625 Hannover, Germany (Raymondos, Panning, Piepenbrock)Search for more papers by this author, and Siegfried Piepenbrock, MDMedizinische Hochschule Hannover; 30625 Hannover, Germany (Raymondos, Panning, Piepenbrock)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-134-9_Part_1-200105010-00024 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:Paret and colleagues speculate that the effects of endotracheal adrenaline may cause β2-mediated hypotension that could be deleterious during cardiac arrest. In our study, the frequency of initial decrease in blood pressure did not differ after airway administration of adrenaline compared with intravenous administration. Blood pressure decreased by 10% in 4 of 34 patients 30 seconds after airway-administered adrenaline but also decreased by 10% in 6 of 34 patients after intravenously administered adrenaline (P > 0.2). This indicates that the blood pressure decrease is not related to the route of adrenaline administration but may be associated with the plasma adrenaline ...References1. McCrirrick A, Kestin I. Haemodynamic effects of tracheal compared with intravenous adrenaline. Lancet. 1992;340:868-70. [PMID: 0001357295] CrossrefMedlineGoogle Scholar2. Paret G, Vaknin Z, Ezra D, Ben-Abraham R, Manistersky Y, Vardi A, Lotan D, et al . Endotracheal adrenaline: should the recommended dose be reconsidered? Journal of Prehospital Care. 1998;2:1-5. MedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Konstantinos Raymondos, MD; Bernhard Panning, MD; Siegfried Piepenbrock, MDAffiliations: Medizinische Hochschule Hannover; 30625 Hannover, Germany (Raymondos, Panning, Piepenbrock) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoAbsorption and Hemodynamic Effects of Airway Administration of Adrenaline in Patients with Severe Cardiac Disease Konstantinos Raymondos , Bernhard Panning , Martin Leuwer , Guido Brechelt , Thomas Korte , Michael Niehaus , Jürgen Tebbenjohanns , and Siegfried Piepenbrock Airway Adrenaline in Patients with Severe Cardiac Disease Gideon Paret , Danny Lotan , and Zohar Barzilay Airway Adrenaline in Patients with Severe Cardiac Disease Gideon Paret , Danny Lotan , and Zohar Barzilay Metrics 1 May 2001Volume 134, Issue 9_Part_1Page: 797-798KeywordsBlood plasmaBlood pressureEpinephrineHeartHeart diseasesHypotensionLungsRoutes of administrationVasoconstrictionVasopressors ePublished: 1 May 2001 Issue Published: 1 May 2001 Copyright & PermissionsCopyright © 2001 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...