Caplan's Syndrome
Authors: WILLIAM K. C. MORGAN
Journal: Annals of Internal Medicine (1961)

Case Reports1 October 1961Caplan's SyndromeAn Interesting Clinico-pathological OccurrenceWILLIAM K. C. MORGAN, M.D., M.R.C.P.E.WILLIAM K. C. MORGAN, M.D., M.R.C.P.E.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-55-4-667 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn 1953, Caplan described a new syndrome in which rheumatoid arthritis was associated with nodular fibrosis of the lungs (1). This condition resembled progressive massive fibrosis or conglomeration of the shadows, as it is more commonly known in the United States, but had distinctive features. A later publication studied the epidemiology of Caplan's syndrome and added some further knowledge to an interesting clinico-pathological occurrence (2). A patient with this syndrome is described here. It is pertinent to note that this patient had been seen on numerous occasions in several clinics over a period of years, without the syndrome being recognized...References1. CAPLAN A: Certain unusual radiological appearances in chests of coalminers suffering from rheumatoid arthritis. Thorax 8: 29, 1953. CrossrefMedlineGoogle Scholar2. MIALLCAPLANCOCHRANEKILPATRICKOLDHAM WEAALGSPD: Epidemiological study of rheumatoid arthritis associated with characteristic chest X-ray appearances in coal workers. Brit. Med. J. 2: 1231, 1953. CrossrefMedlineGoogle Scholar3. KANTORMORROW MCS: Caplan's syndrome. Amer. Rev. Resp. Dis. 78: 274, 1958. Google Scholar4. GOUGHRIVERSSEAL JDRM: Pathological studies of modified pneumoconiosis in coalminers with rheumatoid arthritis. Thorax 10: 9, 1955. CrossrefMedlineGoogle Scholar5. RICKARDSBARRETT AGGM: Rheumatoid lung changes associated with asbestosis. Thorax 13: 185, 1958. CrossrefMedlineGoogle Scholar6. CAMPBELL JA: A case of Caplan's syndrome in a boiler scaler. Thorax 13: 177, 1958. CrossrefMedlineGoogle Scholar7. DUBOISBOTELHOBEDELLMARSHALLCOMROE ABSYGNRJH: A rapid plethysmographic method for measuring thoracic gas volume. J. Clin. Invest. 35: 322, 1956. CrossrefMedlineGoogle Scholar8. DUBOISBOTELHOCOMROE ABSYJH: A new method for measuring airway resistance in man using a body plethysmograph. J. Clin. Invest. 35: 327, 1956. CrossrefMedlineGoogle Scholar9. WATSONBLACKDOIGNAGEL SCHMIDT AJJATG: Pneumoconiosis in carbon electrode workers. Brit. J. Industr. Med. 16: 274, 1959. MedlineGoogle Scholar10. FLETCHERMANNDAVIESCOCHRANEGILSONHUGH-JONES CMKJIALJCP: Classification of the radiological appearances of coalminers' pneumoconiosis. J. Fac. Radiol. (Lond.) 1: 40, 1949. CrossrefGoogle Scholar11. International Classification of Pneumoconiosis. International Conference of Experts on Pneumoconiosis, Sydney, Australia, 1950. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: WILLIAM K. C. MORGAN, M.D., M.R.C.P.E.Affiliations: Baltimore, MarylandReceived for publication October 31, 1960.Requests for reprints should be addressed to William K. Morgan, M.D., University of Maryland School of Medicine, Section for Pulmonary Diseases, Baltimore 1, Maryland. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byCytokine alteration and speculated immunological pathophysiology in silicosis and asbestos-related diseasesDie Silikose (Anthrakosilikose)Rheumatoid pneumoconiosisRheumatoid Pneumoconiosis (Caplan's Disease)Die adrenocorticale funktion, eine determinante der silikoseentwicklung?Pulmonary Dysfunction in Rheumatoid Arthritis and Systemic Lupus ErythematosusCaplan's syndrome 1 October 1961Volume 55, Issue 4Page: 667-672KeywordsArthritisClinical epidemiologyFibrosisLungsPneumoconiosesPulmonary fibrosisRheumatoid arthritis ePublished: 1 December 2008 Issue Published: 1 October 1961 PDF downloadLoading ...