Effects of Dietary Protein on Renal Disease
Authors: Hans-Henrik Parving
Journal: Annals of Internal Medicine (1997)

Letters15 February 1997Effects of Dietary Protein on Renal DiseaseHans-Henrik Parving, MDHans-Henrik Parving, MDSteno Diabetes Center, Copenhagen, DenmarkAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-126-4-199702150-00015 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Pedrini and colleagues [1] recently did a meta-analysis of the effect of dietary protein restriction on the progression of diabetic and nondiabetic renal disease. They concluded that "dietary protein restriction effectively slows the progression of both diabetic and nondiabetic renal diseases." The authors accepted different designs (randomized, controlled studies for nondiabetic renal disease and nonrandomized crossover studies for two of five analyses of diabetic renal disease) and trial end points (renal failure or death for nondiabetic renal disease, and urinary albumin level or a decline in glomerular filtration rate or creatinine clearance for diabetic renal disease).The ...References1. Pedrini MT, Levey AS, Lau J, Chalmers TC, Wang PH. The effect of dietary protein restriction on the progression of diabetic and nondiabetic renal diseases: a meta-analysis. Ann Intern Med. 1995; 124:627-32. Google Scholar2. Levey AS, Gassman JJ, Hall PM, Walker WG. Assessing the progression of renal disease in clinical studies: effect of duration of follow-up and regression to the mean. J Am Soc Nephrol. 1991; 1:1087-94. Google Scholar3. Levey AS, Bosch JP, Coggins CH, Greene T, Mitch WE, Schluchter MD, et al. Effects of diet and antihypertensive therapy on creatinine clearance and serum creatinine concentration in the MDRD Study. Modification of Diet in Renal Disease Study Group. J Am Soc Nephrol. 1996; 7:556-65. Google Scholar4. Parving HH. Low-protein diet and progression of renal disease in diabetic nephropathy [Letter]. Lancet. 1990; 335:411. Google Scholar5. Parving HH. Protein restriction and renal failure in diabetes mellitus. N Engl J Med. 1991; 324:1743-4. Google Scholar Author, Article, and Disclosure InformationAuthors: Hans-Henrik Parving, MDAffiliations: Steno Diabetes Center, Copenhagen, Denmark PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDiabetic NephropathyDiabetic NephropathyManagement of oropharyngeal and esophageal candidiasis in patients with HIV infectionDiabetic NephropathyInvasive Oesophageal CandidiasisEffect of dietary protein restriction on prognosis in patients with diabetic nephropathyDiabetic nephropathy: Prevention and treatmentNon-Glycaemic Intervention in Diabetic Nephropathy: The Role of Dietary Protein IntakeNon-Glycaemic Intervention in Diabetic Nephropathy: The Role of Dietary Protein Intake 15 February 1997Volume 126, Issue 4Page: 330-331KeywordsCreatinineDiabetes mellitusDietGlomerular filtration rateInsulinMicroalbuminuriaProteinsRenal analysisRenal diseasesRenal failure ePublished: 15 August 2000 Issue Published: 15 February 1997 Copyright & PermissionsCopyright © 1997 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...