Chickee, The Copper
Authors: FRANK A. OSKI
Journal: Annals of Internal Medicine (1970)

Editorial Notes1 September 1970Chickee, The CopperFRANK A. OSKI, M.D.FRANK A. OSKI, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-73-3-485 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptFor those on the distal side of the generation gap the term "Chickee, the cops" was an admonition to be on guard. Elsewhere in this issue of the ANNALS convincing evidence of another danger of copper is presented. Manzler and Schreiner (1) describe the acute hemolytic anemia accidentally induced by contamination of dialysate solution with copper; Deiss, Lee, and Cartwright (2) describe the hemolytic anemia deriving from the abnormal copper metabolism of Wilson's disease.The ingestion, either accidently or by design, of copper-containing solutions has long been recognized to produce a clinical picture characterized by nausea, vomiting, epigastric pain, a...References1. MANZLERSCHREINER AA: Copper-induced acute hemolytic anemia: a new complication of hemodialysis. Ann Intern Med 73:409-412, 1970 LinkGoogle Scholar2. DEISSLEECARTWRIGHT AGG: Hemolytic anemia in Wilson's disease. Ann Intern Med 73:413-418, 1970 LinkGoogle Scholar3. TODDTHOMPSON FR: Studies on chronic copper poisoning. II. Biochemical studies on blood of sheep during haemolytic crisis. Brit Vet J 119:161-173, 1963 CrossrefGoogle Scholar4. GOLDBERGWILLIAMSJONES ACR: Studies on copper metabolism. XXII. Haemolytic anaemia in chickens induced by administration of copper. J Lab Clin Med 48:442-453, 1956 MedlineGoogle Scholar5. ROBERTS R: Hemolytic anemia associated with copper sulfate poisoning. Mississippi Doctor 33:292-294, 1956 MedlineGoogle Scholar6. HOLTZMANELLIOTTHELLER NDR: Copper intoxication. New Eng J Med 275:347-352, 1966 CrossrefMedlineGoogle Scholar7. MCINTYRECLINKLEVI NHA: Hemolytic anemia in Wilson's disease. New Eng J Med 276:439-444, 1967 CrossrefMedlineGoogle Scholar8. CARR-SAUNDERSLAURENCE EB: Wilson's disease presenting as an acute haemolytic anaemia. Proc Roy Soc Med 58:614-615, 1965 CrossrefMedlineGoogle Scholar9. GUBLERLAHEYCARTWRIGHT CMG: Studies on copper metabolism. IX. Transportation of copper in blood. J Clin Invest 32:405-414, 1953 CrossrefMedlineGoogle Scholar10. JACOBSCORSON MS: Effect of copper on glycerol transport in mammalian erythrocytes. Biol Bull 67:325, 1934 Google Scholar11. SZASZARKYGARDOS IIC: Studies on the mechanism maintaining biconcave shape of human erythrocytes. Folia Hematologica 89:501, 1968 Google Scholar12. BOWLERDUNCAN KC: The effect of copper on membrane enzymes. Biochim Biophys Acta 196:116-119, 1970 CrossrefMedlineGoogle Scholar13. SALVATIAMBROGIONITENTONI AML: The autoxidation of hemoglobin. Effect of copper, Ital J Biochem 18:1-18, 1969 MedlineGoogle Scholar14. FAIRBANKS V: Copper sulfate-induced hemolytic anemia. Arch Intern Med (Chicago) 120:428-432, 1967 CrossrefMedlineGoogle Scholar15. METZ E: Mechanism of hemolysis by excess copper (abstract). Clin Res 17:32, 1969 Google Scholar16. BEUTLER E: The hemolytic effect of primaquine and related compounds: a review. Blood 14:103-139, 1959 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: FRANK A. OSKI, M.D.Affiliations: Children's Hospital Philadelphia, Pa. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byUrinary iron loss in the nephrotic syndrome—an unusual cause of iron deficiency with a note on urinary copper losses.The Clinical Significance of Trace Elements in ChildhoodAcute renal failure following copper sulphate intoxicationAcute hemolytic anemia as a presenting manifestation of Wilson diseaseProposed ce:role of copper—molybdenum interaction in iron-deficiency and iron-storage diseasesReview: Relationships of copper and molybdenum to iron metabolismThe Human Toxicity of Certain Trace ElementsDONALD B. LOURIA, M.D., F.A.C.P., MORRIS M. JOSELOW, Ph.D., ANN A. BROWDER, M.D., F.A.C.P. 1 September 1970Volume 73, Issue 3Page: 485-486KeywordsHemolytic anemiaIngestionNauseaVomiting ePublished: 1 December 2008 Issue Published: 1 September 1970 PDF downloadLoading ...