Sex-related Outcome Differences after Acute Myocardial Infarction
Authors: George A. Mensah
Journal: Annals of Internal Medicine (1994)

Letters15 November 1994Sex-related Outcome Differences after Acute Myocardial InfarctionGeorge A. Mensah, Richard S. Cooper, and Youlian LiaoGeorge A. MensahSearch for more papers by this author, Richard S. CooperSearch for more papers by this author, and Youlian LiaoSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-121-10-199411150-00016 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:We were intrigued by the study of Becker and colleagues [1], who showed higher morbidity and mortality rates in women than in men after acute myocardial infarction treated with thrombolytic agents. Older age at the time of myocardial infarction and higher prevalence of diabetes mellitus, hypertension, and previous heart failure in women did not completely explain the observed sex difference in clinical outcomes. These clinical characteristics suggest that left ventricular hypertrophy might be more prevalent in women and may partially explain the differences.Recent data have established left ventricular hypertrophy as a powerful independent predictor of cardiovascular ...References1. Becker RC, Terrin M, Ross R, Knatterud GL, Desvigne-Nickens P, Gore JM, et al. Comparison of clinical outcomes for women and men after acute myocardial infarction. Ann Intern Med. 1994; 120:638-45. Google Scholar2. Ghali JK, Liao Y, Simmons B, Castaner A, Cao G, Cooper RS. The prognostic role of left ventricular hypertrophy in patients with or without coronary artery disease. Ann Intern Med. 1992; 117:831-6. Google Scholar3. Dellsperger KC, Clothier JL, Hartnett JA, Haun LM, Marcus ML. Acceleration of the wavefront of myocardial necrosis by chronic hypertension and left ventricular hypertrophy in dogs. Circ Res. 1988; 63:87-96. Google Scholar4. Koyanagi S, Eastham CL, Harrison DG, Marcus ML. Increased size of myocardial infarction in dogs with chronic hypertension and left ventricular hypertrophy. Circ Res. 1982; 50:55-62. Google Scholar5. Bolognese L, Dellavesa P, Rossi L, Sarasso G, Bongo AS, Scianaro MC. Prognostic value of left ventricular mass in uncomplicated acute myocardial infarction and one-vessel coronary artery disease. Am J Cardiol. 1994; 73:1-5. Google Scholar Author, Article, and Disclosure InformationAuthors: George A. Mensah; Richard S. Cooper; Youlian LiaoAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byUsing Angiotensin Converting Enzyme Inhibitors in African-American Hypertensives: A New Approach to Treating Hypertension and Preventing Target-Organ Damage 15 November 1994Volume 121, Issue 10Page: 815-816KeywordsAcute myocardial infarctionHeart failureHypertensionInfarctionLeft ventricular hypertrophyMorbidityMortalityMyocardial infarctionNecrosisStable coronary artery disease ePublished: 15 August 2000 Issue Published: 15 November 1994 Copyright & PermissionsCopyright © 1994 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...