Viscosupplementation for Osteoarthritis of the Knee
Authors: Federico Navarro-Sarabia, Gabriel Herrero-Beaumont
Journal: Annals of Internal Medicine (2013)

Letters1 January 2013Viscosupplementation for Osteoarthritis of the KneeFederico Navarro-Sarabia, MD and Gabriel Herrero-Beaumont, MDFederico Navarro-Sarabia, MDFrom Hospital Universitario Virgen Macarena, Sevilla, and Fundación Jiménez Díaz, Madrid, Spain.Search for more papers by this author and Gabriel Herrero-Beaumont, MDFrom Hospital Universitario Virgen Macarena, Sevilla, and Fundación Jiménez Díaz, Madrid, Spain.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-158-1-201301010-00019 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:We read Rutjes and colleagues' (1) analysis of the therapeutic effect of intra-articular injections of hyaluronic acid with great interest. We were surprised about the evaluation of our paper (2) in Supplement 6, the table summarizing the methodological characteristics of the studies considered in this meta-analysis. Rutjes and associates' table states that we provided no evidence of the number of randomly assigned or analyzed patients (Figure 2 of our article shows our patients' disposition), that allocation concealment was not adequate (“[a] computer-generated randomised list was used to provide balanced blocks of 4 patients each. Allocation to treatment ...References1. Rutjes AW, Jüni P, da Costa BR, Trelle S, Nüesch E, Reichenbach S. Viscosupplementation for osteoarthritis of the knee: a systematic review and meta-analysis. Ann Intern Med. 2012;157:180-91. [PMID: 22868835] LinkGoogle Scholar2. Navarro-Sarabia F, Coronel P, Collantes E, Navarro FJ, de la Serna AR, Naranjo A, et al. AMELIA study group. A 40-month multicentre, randomised placebo-controlled study to assess the efficacy and carry-over effect of repeated intra-articular injections of hyaluronic acid in knee osteoarthritis: the AMELIA project. Ann Rheum Dis. 2011;70:1957-62. [PMID: 21852252] CrossrefMedlineGoogle Scholar3. Osteoarthritis Research Society International-U.S. Food and Drug Administration Initiative. Accessed at www.oarsi.org/index2.cfm?section=OARSI_Initiatives&content=FDA_OA_Initiative on 5 October 2012. Google Scholar4. European Medicines Agency. Guideline on Clinical Investigation of Medicinal Products Used in the Treatment of Osteoarthritis. London: European Medicines Agency; 20 January 2010. Accessed at www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2009/09/WC500003440.pdf on 4 October 2012. Google Scholar5. Herrero-Beaumont G, Roman-Blas JA, Castañeda S, Jimenez SA. Primary osteoarthritis no longer primary: three subsets with distinct etiological, clinical, and therapeutic characteristics. Semin Arthritis Rheum. 2009;39:71-80. [PMID: 19589561] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Federico Navarro-Sarabia, MD; Gabriel Herrero-Beaumont, MDAffiliations: From Hospital Universitario Virgen Macarena, Sevilla, and Fundación Jiménez Díaz, Madrid, Spain.Disclosures: Drs. Navarro-Sarabia and Herrero-Beaumont were authors of the AMELIA (Osteoarthritis Modifying Effects of Long-Term Intra-articular Adant) project (2) and received research funds from Tedec Meiji Farma SA as study investigators. Dr. Navarro-Sarabia also received payment for lectures including service on speakers bureaus from Tedec Meiji Farma SA. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoViscosupplementation for Osteoarthritis of the Knee Anne W.S. Rutjes , Peter Jüni , Bruno R. da Costa , Sven Trelle , Eveline Nüesch , and Stephan Reichenbach Viscosupplementation for Osteoarthritis of the Knee Peter Jüni , Anne W.S. Rutjes , Bruno R. da Costa , and Stephan Reichenbach Metrics Cited byAn update on the up and coming therapies to treat osteoarthritis, a multifaceted disease 1 January 2013Volume 158, Issue 1Page: 74-75KeywordsClinical trialsConflicts of interestExerciseFood and Drug AdministrationIntent to treat analysisKneesOsteoarthritisPhysical functioningResearch fundingSafety ePublished: 1 January 2013 Issue Published: 1 January 2013 Copyright & PermissionsCopyright © 2013 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...