Captopril-Induced Renal Insufficiency and the Role of Sodium Balance
Authors: DONALD E. HRICIK
Journal: Annals of Internal Medicine (1985)

Brief Reports1 August 1985Captopril-Induced Renal Insufficiency and the Role of Sodium BalanceDONALD E. HRICIK, M.D.DONALD E. HRICIK, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-103-2-222 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAcute reversible renal failure may complicate therapy with Captopril in patients with bilateral renal-artery stenoses or renal-artery stenosis in a solitary kidney (1-6). The concomitant use of diuretic agents in many of the reported cases of captopril-induced renal insufficiency has led to speculation that diuretic therapy or sodium depletion may contribute to the decrement in glomerular filtration rate mediated by angiotensin-converting enzyme inhibitors in the presence of a fixed reduction in renal perfusion pressure (1, 6). To determine the influence of sodium balance on captopril-induced renal insufficiency, the renal hemodynamic effects of Captopril were studied prospectively in a patient with...References1. HRICIK D, BROWNING P, KOPELMAN R, GOORNO W, MADIAS N, and DZAU V. Captopril-induced functional renal insufficiency in patients with bilateral renal-artery stenoses or renal-artery stenosis in a solitary kidney. N Engl J Med. 1983;308:373-76. CrossrefMedlineGoogle Scholar2. CURTIS J, LUKE R, WHELCHEL J, DIETHELM A, JONES P, and DUSTAN H. Inhibition of angiotensin-converting enzyme in renal-transplant recipients with hypertension. N Engl J Med. 1983;308:377-81. CrossrefMedlineGoogle Scholar3. COULIE P, DE PLAEN J, and VAN YPERELE DE STRIHOU C. Captopril-induced acute reversible renal failure. Nephron. 1983;35:108-11. CrossrefMedlineGoogle Scholar4. SILAS J, KLENKA Z, and SOLOMON S. Captopril induced reversible renal failure: a marker of renal artery stenosis affecting a solitary Kidney. Br Med J. 1983;286:1702-3. CrossrefMedlineGoogle Scholar5. MASON J and HILTON P. Reversible renal failure due to Captopril in a patient with transplant artery stenosis. Hypertension. 1983;5:623-7. CrossrefMedlineGoogle Scholar6. WATSON M, BELL G, MUIR A, BUIST T, KELLET R, and PADFIELD P. Captopril/diuretic combinations in severe renovascular disease: a cautionary note [Letter]. Lancet. 1983;2:404-5. CrossrefMedlineGoogle Scholar7. EARLE D and BERLINER R. A simplified clinical procedure for measurement of glomerular filtration rate and renal plasma flow. Proc Soc Exper Biol Med. 1946;62:262. CrossrefMedlineGoogle Scholar8. HALL J, GUYTON A, JACKSON T, COLEMAN T, LOHMEIER T, and TRIPPODO N. Control of glomerular filtration rate by renin-angiotensin system. Am J Physiol. 1977;233:F366-72. MedlineGoogle Scholar9. HALL J, GUYTON A, and COWLEY A. Dissociation of renal blood flow and filtration rate autoregulation by renin depletion. Am J Physiol. 1977;232:F215-21. MedlineGoogle Scholar10. HALL J, COLEMAN T, GUYTON A, BALFE J, and SALGADO H.Intrarenal role of angiotensin II and [des-Asp'] angiotensin II. Am J Physiol. 1979;236:F252-9. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: DONALD E. 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A nephrocentric view of converting-enzyme inhibitionFunctional Renal Insufficiency During Long-Term Therapy with Captopril and Enalapril in Severe Chronic Heart FailureMILTON PACKER, M. D., WAI HUNG LEE, M.D., NORMA MEDINA, R.N., MADELINE YUSHAK, R.N., PAUL D. KESSLER, M.D.Antihypertensive drugsEnalapril in the Management of Hypertension Associated With Renal Artery StenosisAdverse Reactions with Angiotensin Converting Enzyme (ACE) InhibitorsCaptopril and Impaired Renal FunctionVITTORIO E. ANDREUCCI, M.D., GIUSEPPE CONTE, M.D., ANTONIO DAL CANTON, M.D.Captopril-Induced Renal InsufficiencyAARON SPITAL, M.D.Treatment of Congestive Heart Failure 1 August 1985Volume 103, Issue 2 Page: 222-223 Keywords Angiotensin converting enzyme inhibitor Diuretics Glomerular filtration rate Hemodynamics Hospital medicine Kidneys Renal failure Sodium Stenosis ePublished: 1 December 2008 Issue Published: 1 August 1985 PDF downloadLoading ...