Hepatitis-B Prevention and Gamma Globulin
Authors: BARRY KISLOFF
Journal: Annals of Internal Medicine (1973)

Letters, Comments, and Corrections1 January 1973Hepatitis-B Prevention and Gamma GlobulinBARRY KISLOFF, M.D.BARRY KISLOFF, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-78-1-151 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: It was disheartening to read your publication of the Public Health Advisory Committee's Recommendations (pages 427-430, September 1972) concerning the prophylaxis of viral hepatitis.Whereas the recommendations are correct insofar as they go, the Committee has apparently chosen to ignore completely certain data that have recently been published.Although human immune globulin given as an intramuscular injection after exposure seems of dubious value in the prevention of type B (HAA + ) hepatitis, recent work by Katz, Rodriguez, and Ward (1) shows that even standard gamma globulin modified for intravenous administration has a definitive role in prophylaxis...References1. KATZRODRIGUEZWARD RJR: Post transfusion hepatitis: effect of modified gamma globulin added to blood in vitro. N Engl J Med 285:925-932, 1971 CrossrefMedlineGoogle Scholar2. Prophylactic gamma globulin for prevention of endemic hepatitis. Effects of US gamma globulin upon the incidence of viral hepatitis and other infectious diseases in US soldiers abroad. Arch Intern Med 128:723-738, 1971 CrossrefMedlineGoogle Scholar3. GINSBERGCONRADBANCROFT AMW: Prevention of endemic HAA-positive hepatitis with gamma globulin. Use of a simple radioimmune assay to detect HAA. N Engl J Med 286:562-566, 1972 CrossrefMedlineGoogle Scholar1. KATZRODRIGUEZWARD RJR: Post-transfusion hepatitis: effect of modified gamma globulin added to blood in vitro. N Engl J Med 285:925-932, 1971 CrossrefMedlineGoogle Scholar2. Prophylactic gamma globulin for prevention of endemic hepatitis. Effect of US gamma globulin upon the incidence of viral hepatitis and other infectious diseases in US soldiers abroad. Arch Intern Med 128:723-738, 1971 CrossrefMedlineGoogle Scholar3. GINSBERGCONRADBANCROFT AMW: Prevention of endemic HAA-positive hepatitis with gamma globulin. Use of a simple radioimmune assay to detect HAA. N Engl J Med 286:562-566, 1972 CrossrefMedlineGoogle Scholar1. Immune serum globulin for protection against viral hepatitis. Recommendation of the Public Health Service Advisory Committee on Immunization Practices. Ann Intern Med 77:427-430, 1972 LinkGoogle Scholar2. GROSSMANSTEWARTSTOKES ESJ: Post-transfusion hepatitis in battle casualties and study of its prophylaxis by means of human immune serum globulin. JAMA 129:991-994, 1945 CrossrefMedlineGoogle Scholar3. MIRICKWARDMCCOLLUM GRR: Modification of post-transfusion hepatitis by gamma globulin. N Engl J Med 273:59-65, 1965 CrossrefMedlineGoogle Scholar4. KATZRODRIGUEZWARD RJR: Post-transfusion hepatitis. Effect of modified gamma globulin added to blood in vitro. N Engl J Med 285:925-932, 1971 CrossrefMedlineGoogle Scholar5. HOLLANDROBINSONMORROW PRA: γ-globulin in the prophylaxis of post-transfusion hepatitis. JAMA 196:471-474, 1966 CrossrefMedlineGoogle Scholar6. A Prospective Cooperative Study: Risk of post-transfusion hepatitis in the United States. JAMA 220:692-701, 1972 CrossrefMedlineGoogle Scholar7. CONRAD M: Post-transfusion hepatitis, in Hepatitis and Blood Transfusion, edited by VYAS GN, PERKINS HA, SCHMID R. New York, Grune and Stratton, 1972, pp. 367-369 Google Scholar8. Prophylactic gamma globulin for prevention of endemic hepatitis. Effects of US gamma globulin upon the incidence of viral hepatitis and other infectious diseases in US soldiers abroad. Arch Intern Med 128:723-738, 1961 CrossrefMedlineGoogle Scholar9. GINSBERGCONRADBANCROFT AMW: Prevention of endemic HAA positive hepatitis with gamma globulin. Use of a simple radioimmune assay to detect HAA. N Engl J Med 286:562-566, 1972 CrossrefMedlineGoogle Scholar10. KRUGMANGILESHAMMON SJJ: Viral hepatitis, type B (MS-2 strain). Prevention with specific hepatitis B immune serum globulin. JAMA 218:1655-1670, 1971 CrossrefGoogle Scholar11. DANECAMERONBRIGGS DCM: Virus-like particles in serum of patients with Australia-antigen-associated hepatitis. Lancet 1:695-698, 1970 CrossrefMedlineGoogle Scholar12. ZUCKERMAN A: Viral hepatitis. Natural history of the disease, in Hepatitis and Blood Transfusion, edited by VYAS GN, PERKINS HA, SCHMID R. New York, Grune & Stratton, 1972, pp. 19-22 Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: BARRY KISLOFF, M.D.Affiliations: Northwestern University Medical Center Chicago, Ill. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 January 1973Volume 78, Issue 1Page: 151-153KeywordsGlobulinsHepatitisHepatitis AIntramuscular injectionsPrevention, policy, and public healthProphylaxis ePublished: 1 December 2008 Issue Published: 1 January 1973 PDF downloadLoading ...