Cardiac Tachypacing for Severe Refractory Idiopathic Orthostatic Hypotension
Authors: Peter Weissmann, Michael T. Chin, Arthur J. Moss
Journal: Annals of Internal Medicine (1992)

Brief Reports15 April 1992Cardiac Tachypacing for Severe Refractory Idiopathic Orthostatic HypotensionPeter Weissmann, MD, Michael T. Chin, MD, PhD, Arthur J. Moss, MDPeter Weissmann, MDSearch for more papers by this author, Michael T. Chin, MD, PhDSearch for more papers by this author, Arthur J. Moss, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-116-8-650 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn 1925, Bradbury and Eggleston described three patients with marked postural decline in the blood pressure, fixed heart rate, anhidrosis, nocturnal polyuria, and impotence (1). This idiopathic disorder is caused by primary autonomic nervous system dysfunction, which may be central with multiple neurologic defects (the Shy-Drager Syndrome) (2) or peripheral with a defect limited to the efferent sympathetic nerves (3). Orthostatic hypotension usually develops insidiously over a period of years and eventually becomes functionally disabling. Patients experience orthostatic faintness and syncope, especially in the morning after they awaken.Therapy for this disorder is unsatisfactory and usually involves a multifaceted approach...References1. Bradbury S and Eggleston C. Postural hypotension: a report of three cases. Am Heart J. 1925;l;73-86. CrossrefGoogle Scholar2. Shy G and Drager G. A neurological syndrome associated with orthostatic hypotension. Am A Arch Neurol. 1960;2:511-27. CrossrefMedlineGoogle Scholar3. Ziegler M, Lake C, and Kopin I. The sympathetic-nervous-system defect in primary orthostatic hypotension. N Engl J Med. 1977;296:293-7. CrossrefMedlineGoogle Scholar4. Robertson D and Robertson R. Orthostatic hypotension-diagnosis and therapy. Mod Concepts Cardiovasc Dis. 1985;54:7-11. Google Scholar5. Onrot J, Goldberg M, Hollister A, Biaggioni I, Robertson R, and Robertson D. Management of chronic orthostatic hypotension. Am J Med. 1986;80-454-64. CrossrefMedlineGoogle Scholar6. Management of orthostatic hypotension [Editorial]. Lancet. 1987;1:197-8. MedlineGoogle Scholar7. Moss A, Glaser W, and Topol E. Atrial tachypacing in the treatment of a patient with primary orthostatic hypotension. N Engl J Med. 1980;302:1456-7. CrossrefMedlineGoogle Scholar8. Goldberg M, Robertson R, and Robertson D. Atrial tachypacing for primary orthostatic hypotension. N Engl J Med. 1980;303:885-6. CrossrefMedlineGoogle Scholar9. Kristinsson A. Programmed atrial pacing for orthostatic hypotension. Acta Med Scand. 1983;214:79-83. CrossrefMedlineGoogle Scholar10. Brevetti G, Chiariello M, Giudice P, De Michele G, Mansi D, and Campanula G. Effective treatment of orthostatic hypotension by propanolol in the Shy-Drager syndrome. Am Heart J. 1981;102:938-41. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: Peter Weissmann, MD; Michael T. Chin, MD, PhD; Arthur J. Moss, MDFrom the University of Rochester School of Medicine and Dentistry, Rochester, New York. For current author addresses, see end of text. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byIndications for Permanent and Temporary Cardiac PacingPacemakers and SyncopeTransient Overdrive Pacing Upon Standing Prevents Orthostatic Hypotension in Elderly Pacemaker Patients with Chronotropic IncompetenceEffects of Atrial Tachypacing on Symptoms and Blood Pressure in Severe Orthostatic HypotensionBlood Pressure Response to Transition from Supine to Standing Posture Using an Orthostatic Response AlgorithmTreatment of Patients with Neurogenic Orthostatic HypotensionEnhanced Rate Response Algorithm for Orthostatic Compensation PacingManagement of postural hypotensionChronische arterielle HypotensionSuccessful Treatment of Severe Orthostatic Hypotension with Cardiac Tachypacing in Dual Chamber PacemakersTreatment of Malignant Primary Vasodepressive Neurocardiogenic Syncope with a Rate Responsive Pacemaker Driven by Heart ContractilitySyncope: Current diagnosis and treatmentDYSAUTONOMIC AND REFLEX SYNCOPE SYNDROMESFluoxetine hydrochloride for the treatment of severe refractory orthostatic hypotensionAdaptive Rate Pacing Controlled by Right Ventricular Preejection Interval for Severe Refractory Orthostatic Hypotension 15 April 1992Volume 116, Issue 8 Page: 650-651 Keywords Autonomic nervous system Blood pressure Dentistry Erectile dysfunction Heart rate Hypotension Nerves Sympathetic nervous system Syncope ePublished: 1 December 2008 Issue Published: 15 April 1992 PDF downloadLoading ...