Preventing Alzheimer Disease and Cognitive Decline
Authors: Chengxuan Qiu, Miia Kivipelto, Laura Fratiglioni
Journal: Annals of Internal Medicine (2011)

Letters1 February 2011Preventing Alzheimer Disease and Cognitive DeclineChengxuan Qiu, MD, PhD, Miia Kivipelto, MD, PhD, and Laura Fratiglioni, MD, PhDChengxuan Qiu, MD, PhDFrom Aging Research Center, Karolinska Institutet, SE-11330 Stockholm, Sweden.Search for more papers by this author, Miia Kivipelto, MD, PhDFrom Aging Research Center, Karolinska Institutet, SE-11330 Stockholm, Sweden.Search for more papers by this author, and Laura Fratiglioni, MD, PhDFrom Aging Research Center, Karolinska Institutet, SE-11330 Stockholm, Sweden.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-154-3-201102010-00014 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Daviglus and colleagues (1) report that no firm conclusions currently can be drawn about the association of any modifiable risk factors with Alzheimer disease and, thus, that recommendations for preventing this condition cannot be made. This conclusion is essentially based on a systematic review from an independent panel of health professionals and public representatives who do not specialize in Alzheimer disease, plus presentations by and discussions with the world's leading experts on this condition (2). The reviewers examined the extensive literature investigating the modifiable risk factors for Alzheimer disease but concluded that the quality of evidence supporting ...References1. Daviglus ML, Bell CC, Berrettini W, Bowen PE, Connolly ES, Cox NJ, et al. National Institutes of Health State-of-the-Science Conference statement: preventing Alzheimer disease and cognitive decline. Ann Intern Med. 2010;153:176-81. [PMID: 20547888] LinkGoogle Scholar2. Williams JW, Plassman BL, Burke J, Holsinger T, Benjamin S. Preventing Alzheimer's Disease and Cognitive Decline. Rockville, MD: Agency for Healthcare Research and Quality; 2010. Google Scholar3. Qiu C, Winblad B, Fratiglioni L. The age-dependent relation of blood pressure to cognitive function and dementia. Lancet Neurol. 2005;4:487-99. [PMID: 16033691] CrossrefMedlineGoogle Scholar4. Qiu C, Xu W, Fratiglioni L. Vascular and psychosocial factors in Alzheimer's disease: epidemiological evidence toward intervention. J Alzheimers Dis. 2010;20:689-97. [PMID: 20182015] CrossrefMedlineGoogle Scholar5. Launer LJ, Hughes T, Yu B, Masaki K, Petrovitch H, Ross GW, et al. Lowering midlife levels of systolic blood pressure as a public health strategy to reduce late-life dementia: perspective from the Honolulu Heart Program/Honolulu Asia Aging Study. Hypertension. 2010;55:1352-9. [PMID: 20404223] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Aging Research Center, Karolinska Institutet, SE-11330 Stockholm, Sweden.Disclosures: None disclosed. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoNational Institutes of Health State-of-the-Science Conference Statement: Preventing Alzheimer Disease and Cognitive Decline Martha L. Daviglus , Carl C. Bell , Wade Berrettini , Phyllis E. Bowen , E. Sander Connolly Jr. , Nancy Jean Cox , Jacqueline M. Dunbar-Jacob , Evelyn C. Granieri , Gail Hunt , Kathleen McGarry , Dinesh Patel , Arnold L. Potosky , Elaine Sanders-Bush , Donald Silberberg , and Maurizio Trevisan Preventing Alzheimer Disease and Cognitive Decline Frederick Naftolin and S. Mitchell Harman Preventing Alzheimer Disease and Cognitive Decline Martha L. Daviglus , Carl C. Bell , Wade Berrettini , Phyllis E. Bowen , E. Sander Connolly Jr. , Nancy Jean Cox , Jacqueline M. Dunbar-Jacob , Evelyn C. Granieri , Gail Hunt , Kathleen McGarry , Dinesh Patel , Arnold L. Potosky , Elaine Sanders-Bush , Donald Silberberg , and Maurizio Trevisan Metrics Cited ByShared risk and protective factors between Alzheimer's disease and ischemic stroke: A population‐based longitudinal studyIncidence and predictors of mild cognitive impairment (MCI) within a multi-ethnic Asian populace: a community-based longitudinal studyAdvances in the prevention of Alzheimer's disease and dementiaEpidemiological findings of vascular risk factors in Alzheimer’s disease: implications for therapeutic and preventive intervention 1 February 2011Volume 154, Issue 3Page: 211KeywordsAlzheimer diseaseAntihypertensive drug therapyDementiaHypercholesterolemiaMedical conditionsMedical risk factorsPrevention, policy, and public healthRisk managementSystematic reviews ePublished: 1 February 2011 Issue Published: 1 February 2011 CopyrightCopyright © 2011 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...