Exercise and Peripheral Arterial Disease
Authors: Dae Hyun Kim
Journal: Annals of Internal Medicine (2006)

Letters2 May 2006Exercise and Peripheral Arterial DiseaseDae Hyun Kim, MD, MPHDae Hyun Kim, MD, MPHFrom the Jefferson Medical College, Philadelphia, PA 19107.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-144-9-200605020-00017 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Dr. McDermott and colleagues (1) found that self-directed walking exercise at least 3 times weekly was associated with a slower rate of functional decline in patients with peripheral arterial disease (PAD) after adjusting for sociodemographic and clinical characteristics, including aspirin, statin, and angiotensin-converting enzyme inhibitor use. They also took into consideration that a proportion of patients benefited from participating in supervised exercise programs. They did not, however, adjust for the use of pharmacologic interventions for claudication, such as pentoxifylline and cilostazol, which might have more significant and direct effects on functional performance than those seen with aspirin, ...References1. McDermott MM, Liu K, Ferrucci L, Criqui MH, Greenland P, Guralnik JM, et al. Physical performance in peripheral arterial disease: a slower rate of decline in patients who walk more. Ann Intern Med. 2006;144:10-20. [PMID: 16389250] LinkGoogle Scholar2. Girolami B, Bernardi E, Prins MH, Ten Cate JW, Hettiarachchi R, Prandoni P, et al. Treatment of intermittent claudication with physical training, smoking cessation, pentoxifylline, or nafronyl: a meta-analysis. Arch Intern Med. 1999;159:337-45. [PMID: 10030306] CrossrefMedlineGoogle Scholar3. Beebe HG, Dawson DL, Cutler BS, Herd JA, Strandness DE, Bortey EB, et al. A new pharmacological treatment for intermittent claudication: results of a randomized, multicenter trial. Arch Intern Med. 1999;159:2041-50. [PMID: 10510990] CrossrefMedlineGoogle Scholar4. Dawson DL, Cutler BS, Meissner MH, Strandness DE. Cilostazol has beneficial effects in treatment of intermittent claudication: results from a multicenter, randomized, prospective, double-blind trial. Circulation. 1998;98:678-86. [PMID: 9715861] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From the Jefferson Medical College, Philadelphia, PA 19107.Disclosures: None disclosed. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoPhysical Performance in Peripheral Arterial Disease: A Slower Rate of Decline in Patients Who Walk More Mary McGrae McDermott , Kiang Liu , Luigi Ferrucci , Michael H. Criqui , Philip Greenland , Jack M. Guralnik , Lu Tian , Joseph R. Schneider , William H. Pearce , Jin Tan , and Gary J. Martin Exercise and Peripheral Arterial Disease Steven T. Johnson and Rhonda C. Bell Exercise and Peripheral Arterial Disease Mary M. McDermott , Kiang Liu , and Lu Tian Metrics Cited byModes of exercise training for intermittent claudicationModes of exercise training for intermittent claudication 2 May 2006Volume 144, Issue 9Page: 699KeywordsCardiovascular therapyExerciseExercise therapyPhosphodiesterasesQuality of lifeStatinsVasodilatorsWalking ePublished: 2 May 2006 Issue Published: 2 May 2006 Copyright & PermissionsCopyright © 2006 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...