Epstein-Barr Virus, Leukemia, and Mononucleosis
Authors: DAVID A. STEVENS
Journal: Annals of Internal Medicine (1970)

Letters and Comments1 August 1970Epstein-Barr Virus, Leukemia, and MononucleosisDAVID A. STEVENS, M.D.DAVID A. STEVENS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-73-2-341_3 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: I read with interest the report of concurrent acute myelocytic leukemia and infectious mononucleosis (1). We have reported a similar case of concurrent acute lymphocytic leukemia and infectious mononucleosis and documented the seroconversion to Epstein-Barr (EB) virus by immunofluorescence (2). As a result of experience with this case and a similar case that came to our attention, my associates and I initiated a study of the concurrence of these two diseases (3). It is of interest that from these cases, unpublished data, serum obtained from previously reported patients (as also referred to by Deardorff, Gerber, and Vogler),...References1. DEARDORFFGERBERVOGLER WPW: Infectious mononucleosis in acute leukemia with rising Epstein-Barr virus antibody titers. Ann Intern Med 72:235-240, 1970 LinkGoogle Scholar2. STEVENSPRYMANAKER DTR: Infectious mononucleosis—always a primary infection with herpes-type virus? J Nat Cancer Inst 44:533-537, 1970 MedlineGoogle Scholar3. STEVENSLEVINELEE DPS: Concurrent infectious mononucleosis and acute leukemia. Report of cases, review of the literature, and serological studies with the herpes-type virus (EB virus). Amer J Med. In press Google Scholar4. EVANSNIEDERMANMCCOLLUM AJR: Seroepidemiologic studies of infectious mononucleosis with EB virus. New Eng J Med 279:1121-1127, 1968 CrossrefMedlineGoogle Scholar5. HENLEHENLEDIEHL GWV: Relation of Burkitt's tumor associated herpes-type virus to infectious mononucleosis. Proc Nat Acad Sci 59:94-101, 1968 CrossrefMedlineGoogle Scholar6. NIEDERMANMCCOLLUMHENLE JRG: Infectious mononucleosis: clinical manifestations in relation to the EB virus. JAMA 203:205-209, 1968 CrossrefMedlineGoogle Scholar1. Editorial: E.B. virus, infectious mononucleosis, and Burkitt lymphoma. Lancet 2:887-888, 1969 MedlineGoogle Scholar2. OLDBOYSEGEERING LEG: Serologic approaches to the study of cancer in animals and in man. Cancer Res 28-1288-1299, 1968 Google Scholar3. O'CONNER G: Persistent immunologic stimulation as a factor in oncogenesis, with special reference to Burkitt's tumor. Amer J Med 48:279-285, 1970 CrossrefMedlineGoogle Scholar4. SELIGMANNFUDENBERGGOOD MHR: A proposed classification of primary immunologic deficiencies. Amer J Med 45:817-825, 1968 CrossrefMedlineGoogle Scholar5. MATHÉAMIELSCHWARZENBERG GJL: Active immunotherapy for acute lymphoblastic leukemia. Lancet 1: 697-699, 1969 CrossrefMedlineGoogle Scholar6. DEARDORFFGERBERVOGLER WPW: Infectious mononucleosis in acute leukemia with rising Epstein-Barr virus antibody titers. Ann Intern Med 72:235-240, 1970 LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Department of Medicine School of Medicine University of California Los Angeles, Calif. 90024 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 August 1970Volume 73, Issue 2Page: 341-342KeywordsAcute myeloid leukemiaEpstein-Barr virusImmunofluorescencePrecursor cells Issue Published: 1 August 1970 PDF DownloadLoading ...