tbuckley/cabot-search huggingface dataset:
Emotional Intelligence Training and Evaluation in Physicians—Reply
Authors: Daisy Grewal
Journal: JAMA (2009)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Exposures of children to organophosphate pesticides and their potential adverse health effects.
Authors: B Eskenazi, A Bradman, R Castorina
Journal: Environmental Health Perspectives (1999)

Recent studies show that young children can be exposed to pesticides during normal oral exploration of their environment and their level of dermal contact with floors and other surfaces. Children living in agricultural areas may be exposed to higher pesticide levels than other children because of pesticides tracked into their homes by household members, by pesticide drift, by breast milk from their farmworker mother, or by playing in nearby fields. Nevertheless, few studies have assessed the extent of children's pesticide exposure, and no studies have examined whether there are adverse health effects of chronic exposure. There is substantial toxicologic evidence that repeated low-level exposure to organophosphate (OP) pesticides may affect neurodevelopment and growth in developing animals. For example, animal studies have reported neurobehavorial effects such as impairment on maze performance, locomotion, and balance in neonates exposed (italic)in utero(/italic) and during early postnatal life. Possible mechanisms for these effects include inhibition of brain acetylcholinesterase, downregulation of muscarinic receptors, decreased brain DNA synthesis, and reduced brain weight in offspring. Research findings also suggest that it is biologically plausible that OP exposure may be related to respiratory disease in children through dysregulation of the autonomic nervous system. The University of California Berkeley Center for Children's Environmental Health Research is working to build a community-university partnership to study the environmental health of rural children. This Center for the Health Assessment of Mothers and Children of Salinas, or CHAMACOS in Monterey County, California, will assess (italic)in utero(/italic) and postnatal OP pesticide exposure and the relationship of exposure to neurodevelopment, growth, and symptoms of respiratory illness in children. The ultimate goal of the center is to translate research findings into a reduction of children's exposure to pesticides and other environmental agents, and thereby reduce the incidence of environmentally related disease.
Curiouser and curiouser
Authors: L. Morrison
Journal: BMJ (2003)

Last week we buried my father in law, David. He was 92 and had had a full life. We put him to rest in a natural woodland site, and it was a joyful day.

His three sons each spoke beside his coffin. Curiosity was a strong theme. He had a never ending curiosity for how things worked—engines, boats, paints, clays, instruments. For about the past 20 years he had professed not to be able to see or hear, yet he skillfully made and mended clocks. Curiosity, apparently, overcame his disabilities. (Selective deafness was also a hypothesis.) He accepted what he could do and not do and went ahead …
Sentinel Lymph Node Biopsy of Oral/Oropharyngeal Squamous Cell Carcinoma
Authors: Gianpiero Manca, Duccio Volterrani, Sara Mazzarri, Sotirios Chondrogiannis, Francesco Giammarile, Domenico Rubello, Patrick M. Colletti
Journal: Clinical Nuclear Medicine (2015)

Manca, Gianpiero MD; Volterrani, Duccio MD; Mazzarri, Sara MD; Chondrogiannis, Sotirios MD; Giammarile, Francesco MD; Rubello, Domenico MD; Colletti, Patrick M. MD Author Information
Head contacts in collegiate football measured with an instrumented mouthguard
Authors: David Camarillo, James Mattson, Michael Flynn, Sheng Yang, Pete Shull, Rebecca Shultz, Gordon Matheson, Daniel Garza
Journal: British Journal of Sports Medicine (2013)

Background The clinical relationship between accumulated head impacts and chronic cognitive dysfunction is under increasing scrutiny. There is therefore a need to track an athlete's accumulation of head impacts. Objective We sought to develop and test an inexpensive wireless device that could be widely used for monitoring blows to the head in football. Design Prospective, descriptive. Setting Stanford University scrimmages. Subjects 16 males from 6 different positions. Methods During four spring practice sessions, players wore mouthguards instrumented with three accelerometers and gyroscopes for measuring head motion. When the acceleration magnitude exceeded 15G (after 110 Hz low-pass filter), an event was recorded. Simultaneously, full-speed scrimmage sessions were video recorded from two perpendicular angles and later analysed for ‘helmet-helmet contacts.’ Plays were only considered if the subject's helmet was struck by the opposing player's helmet at the initial point of contact, or if the subject's helmet sustained “no-contact” at all during the play. Mouthguard events were then synchronised and evaluated during the time period of each play to determine agreement with video data. Results Video analysis yielded 153 helmet-helmet contacts and 402 no-contacts. Mouthguard sensitivity for detecting observed helmet contact at the 15G threshold was 61% (95% CI 0.54 to 0.69) and the specificity was 91% (95% CI 0.88 to 0.93). Overall accuracy was 83%. Conclusion Although the 15G threshold is based on published helmet telemetry clinical studies, 39% of observed helmet-helmet contacts were below this threshold. Further research is required to understand if lower acceleration contacts are clinically relevant, and if they can be accurately detected. Acknowledgements We acknowledge the Stanford athletic training, videography, and football staff for their cooperation as well as X2 Impact Inc. for donation of mouthguards.
GW25-e4356 Apelin Treatment Prevents Hippocampal Inflammation and Oxidative Stress in Hypertensive Mice via Activation of the BDNF/eNOS/NO Signaling
Authors: Hai-Yan Jin, Wei Jin, Ying-Le Xu, Lai-Jiang Chen, Guo-Zhen Lin, Zhen-Zhou Zhang, Xu-Dong Xu, Bei Song, Jiu-Chang Zhong
Journal: Journal of the American College of Cardiology (2014)
Chronic brain inflammation and persistent herpes simplex virus 1 thymidine kinase expression in survivors of syngeneic glioma treated by adenovirus-mediated gene therapy: Implications for clinical trials
Authors: R. A. Dewey, G. Morrissey, C. M. Cowsill, D. Stone, F. Bolognani, N.J.F. Dodd, T. D. Southgate, D. Klatzmann, H. Lassmann, M.G. Castro, P.R. Löwenstein
Journal: Nature Medicine (1999)
Oral essential fatty acid supplementation in atopic dermatitis-a meta-analysis of placebo-controlled trials
Authors: C.J.A.W. Van Gool, M.P.A. Zeegers, C. Thijs
Journal: British Journal of Dermatology (2004)

Journal Article Oral essential fatty acid supplementation in atopic dermatitis—a meta‐analysis of placebo‐controlled trials Get access C.J.A.W. Van Gool, C.J.A.W. Van Gool Department of Epidemiology, Nutrition and Toxicology Research Institute Maastricht (NUTRIM), Maastricht University, Maastricht, the Netherlands C.J.A.W.van Gool PhD. E‐mail: cgoo@eepz.azm.nl Search for other works by this author on: Oxford Academic Google Scholar M.P.A. Zeegers, M.P.A. Zeegers Department of Epidemiology, Nutrition and Toxicology Research Institute Maastricht (NUTRIM), Maastricht University, Maastricht, the Netherlands Search for other works by this author on: Oxford Academic Google Scholar C. Thijs C. Thijs Department of Epidemiology, Nutrition and Toxicology Research Institute Maastricht (NUTRIM), Maastricht University, Maastricht, the Netherlands Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 150, Issue 4, 1 April 2004, Pages 728–740, https://doi.org/10.1111/j.0007-0963.2004.05851.x Published: 01 April 2004 Article history Accepted: 25 September 2003 Published: 01 April 2004
Ethnic Disparities in Diabetes Management and Pay-for-Performance in the UK: The Wandsworth Prospective Diabetes Study
Authors: Christopher Millett, Jeremy Gray, Sonia Saxena, Gopalakrishnan Netuveli, Kamlesh Khunti, Azeem Majeed
Journal: PLoS Medicine (2007)

Background Pay-for-performance rewards health-care providers by paying them more if they succeed in meeting performance targets. A new contract for general practitioners in the United Kingdom represents the most radical shift towards pay-for-performance seen in any health-care system. The contract provides an important opportunity to address disparities in chronic disease management between ethnic and socioeconomic groups. We examined disparities in management of people with diabetes and intermediate clinical outcomes within a multiethnic population in primary care before and after the introduction of the new contract in April 2004. Methods and Findings We conducted a population-based longitudinal survey, using electronic general practice records, in an ethnically diverse part of southwest London. Outcome measures were prescribing levels and achievement of national treatment targets (HbA1c ≤ 7.0%; blood pressure [BP] < 140/80 mm Hg; total cholesterol ≤ 5 mmol/l or 193 mg/dl). The proportion of patients reaching treatment targets for HbA1c, BP, and total cholesterol increased significantly after the implementation of the new contract. The extents of these increases were broadly uniform across ethnic groups, with the exception of the black Caribbean patient group, which had a significantly lower improvement in HbA1c (adjusted odds ratio [AOR] 0.75, 95% confidence interval [CI] 0.57–0.97) and BP control (AOR 0.65, 95% CI 0.53–0.81) relative to the white British patient group. Variations in prescribing and achievement of treatment targets between ethnic groups present in 2003 were not attenuated in 2005. Conclusions Pay-for-performance incentives have not addressed disparities in the management and control of diabetes between ethnic groups. Quality improvement initiatives must place greater emphasis on minority communities to avoid continued disparities in mortality from cardiovascular disease and the other major complications of diabetes.
Physician pay must change
Authors: E. Davies
Journal: BMJ (2013)

“We’re now at a point where the level of spending on healthcare is unsustainable, and the way that doctors are paid is one of the single most important drivers of our escalating healthcare costs.”

So says Steven A Schroeder, chair of The National Commission on Physician Payment Reform and professor of health and healthcare at the University of California, San Francisco.

It’s a hypothesis that will make uncomfortable reading for a …
The English Disease
Authors: J. Crofton
Journal: BMJ (1973)

<h3>Abstract</h3> <h3>Introduction</h3> Polygenic Risk Score (PRS) are powerful summaries of genetic risk alleles that can potentially be used to predict disease outcomes and guide treatment decisions. Hispanics/Latinos suffer from higher rates of Alzheimer’s Disease (AD) and Mild Cognitive Impairment (MCI) compared to non-Hispanic Whites, yet the strongest known genetic risk factor for AD, <i>APOE</i>-<i>ϵ</i>4 allele, has weak association with AD in Hispanics/Latinos. We evaluated PRS constructed based on Genome-Wide Association Studies (GWAS) of AD in predicting MCI in Hispanics/Latinos when accounting for <i>APOE</i> alleles and variants. <h3>Methods</h3> We used summary statistics from four GWAS of AD to construct PRS that predict MCI in 4,189 diverse Hispanics/Latinos (mean age 63 years, 47% males) from the Study of Latinos-Investigation of Neurocognitive Aging. We assessed the PRS associations with MCI in the combined set of people and in groups defined by genetic ancestry and Hispanic/Latino background, and when including and excluding single nucleotide polymorphisms (SNPs) from the <i>APOE</i> gene region. <h3>Results</h3> A PRS constructed based on GWAS of AD in the FINNGEN Biobank was associated with MCI (OR = 1.34, 95% CI [1.15, 1.55]), and its association was mostly driven by 158 <i>APOE</i> region SNPs. A PRS constructed based on a multi-ethnic AD GWAS was associated with MCI (OR=1.22, 95% CI [1.08, 1.37]) without including any <i>APOE</i> region SNPs. <i>APOE</i>-<i>ϵ</i>4 and <i>APOE</i>-<i>ϵ</i>2 alleles were not associated with MCI. <h3>Discussion</h3> A combination of <i>APOE</i> region SNPs is associated with MCI in Hispanics/Latinos despite <i>APOE</i>-<i>ϵ</i>4 and <i>APOE</i>-<i>ϵ</i>2 alleles not being associated with MCI.
One-year follow-up of the phagocytic activity of leukocytes after exposure of rats to asbestos and basalt fibers.
Authors: M Hurbánková
Journal: Environmental Health Perspectives (1994)

The phagocytic activity of leukocytes in peripheral blood was investigated after 2, 24, and 48 hr; 1, 2, 4, and 8 weeks; and 6 and 12 months following intraperitoneal administration of asbestos and basalt fibers to Wistar rats. Asbestos and basalt fibers differed in their effects on the parameters studied. Both granulocyte count and phagocytic activity of leukocytes during the 1-year dynamic follow-up in both dust-exposed groups of animals changed in two phases, characterized by the initial stimulation of the acute phase I, followed by the suppression of the parameters in the chronic phase II. Exposure to asbestos and basalt fibers led, in phase II, to impairment of the phagocytic activity of granulocytes. Asbestos fibers also significantly decreased phagocytic activity of monocytes. Exposure to basalt fibers did not affect the phagocytic activity of monocytes in phase II. Results suggest that the monocytic component of leukocytes plays an important role in the development of diseases caused by exposure to fibrous dusts, but basalt fibers have lesser biological effects than asbestos fibers.
Reply to ‘Music Therapy or Music Medicine?’
Authors: Vera Brandes
Journal: Psychotherapy and Psychosomatics (2011)

Letters| June 30 2011 Reply to 'Music Therapy or Music Medicine?' Subject Area: Psychiatry and Psychology Vera Brandes Vera Brandes Research Program Music Medicine, Paracelsus Medical University, Salzburg, Austria Search for other works by this author on: This Site PubMed Google Scholar Psychother Psychosom (2011) 80 (5): 305. https://doi.org/10.1159/000325827 Article history Received: January 12 2011 Accepted: February 12 2011 Published Online: June 30 2011 Content Tools Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Vera Brandes; Reply to 'Music Therapy or Music Medicine?'. Psychother Psychosom 1 July 2011; 80 (5): 305. https://doi.org/10.1159/000325827 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsPsychotherapy and Psychosomatics Search Advanced Search This content is only available via PDF. © 2010 S. Karger AG, Basel2011Copyright / Drug Dosage / DisclaimerCopyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Article PDF first page preview Close Modal You do not currently have access to this content.
ln-111 Labeled Leukocyte Scintigraphy in a Case of Multifocal Candidiasis
Authors: CHRISTOPHER J. PALESTRO, AMARILIS VEGA, CHUN K. KIM, STANLEY J. GOLDSMITH
Journal: Clinical Nuclear Medicine (1990)

The value of indium-111 labeled leukocyte scintigraphy for the diagnosis of infection in the general population is well documented; there is less information available on its role in the evaluation of the immunocompromised patient. In this study, leukocyte scintigraphy was performed on a 31-year-old immunocompromised woman who had a possible intra-abdominal abscess. No abscess was detected, but intense oral, esophageal, gastric, and vaginal uptake was observed. Candida infection was histologically confirmed at all four sites.
Prolonged remission after life‐threatening gastrointestinal hemorrhage from coexistent angiodysplasia and acquired bleeding diathesis
Authors: Timothy J. Woodlock, Charles W. Francis, Jacob M. Rowe, M. Julianne Brown, Victor J. Marder
Journal: American Journal of Hematology (1988)

Abstract A patient with angiodysplasia of the stomach and duodenum developed exceptionally severe and protracted gastrointestinal hemorrhage. Bleeding was intensified by a coexistent acquired hemostatic disorder characterized by decreased platelet aggregation with adenosine diphosphate, collagen, epinephrine and ristocetin, and a decrease in both plasma ristocetin cofactor activity and high‐molecular‐weight von Willebrand factor multimers. Cryoprecipitate infusion corrected the von Willebrand factor defect but did not improve platelet aggregation. Bleeding stopped after prolonged aggressive combined medical and surgical therapy, and the patient had no recurrence of bleeding while followed for 27 months. Hemorrhage from the vascular lesions themselves dominated the clinical picture of this patient and other reported patients with coexistent angiodysplasia and congenital or acquired hemostatic abnormalities.
Sharper focus on uncomplicated pregnancy
Authors: M. Knight
Journal: BMJ (2013)

May help develop and evaluate population interventions

Many studies have identified factors associated with complications of pregnancy, such as maternal age, ethnicity, obesity, smoking, and pre-existing medical conditions.1 2 3 In a linked paper (doi:10.1136/bmj.f6398), Chappell and colleagues take the opposite approach and use information from a large cohort of nulliparous women in Australia and the United Kingdom to investigate factors associated with uncomplicated pregnancy.4 This robust approach is welcome in the context of initiatives to step back from the medicalisation of pregnancy and provides useful information for women, clinicians, and policy makers.

Video Abstract

The authors divide factors associated with uncomplicated pregnancy into those that they consider modifiable—such as raised body mass index, drug misuse before pregnancy, and fruit intake before pregnancy—and those considered not amenable to change, including a family history of hypertension and maternal socioeconomic index. The study is observational and we cannot assume causality, so replication in similarly robust studies may be needed before we consider interventions to help change these modifiable factors. Nevertheless, it is clear that these factors will not be modified by actions during pregnancy alone. Public health …
Mid-Trimester Endovaginal Sonography in Women at High Risk for Spontaneous Preterm Birth
Authors: John Owen
Journal: JAMA (2001)

RETERM BIRTH IS THE MOST IMportant cause of infant morbidity and mortality and complicates 11% of all pregnancies in the United States. 1 Most (80%) of these births result from either spontaneous labor or membrane rupture. 2Since the development of neonatal intensive care units, most neonatal deaths associated with prematurity occur in infants born at less than 32 weeks' gestation, but significant morbidities including sepsis, respiratory distress, and necrotizing enterocolitis do not abate until 35 weeks' gestation, after which neonatal outcomes are generally good. 3,4To date, a prior preterm birth is one of the strongest and most consistent predictors of prematurity, and the risk of recurrence is inversely proportional to the gestational age of the prior delivery. 5,6dovaginal ultrasound is a reliable technology for imaging the cervix and lower uterine segment during pregnancy. 7,8While there is ample evidence that a shortened cervical length is associated with preterm birth, 9-18 it
Consequences of Creation of Arteriovenous Fistula
Authors: Allen D. Meyer
Journal: JAMA (1963)

Serial orthopedic and hemodynamic measurements made in a child before, during, and after the creation of a systemic arteriovenous fistula to promote growth of a shortened leg are reported. The mechanisms and associated clinical phenomena of the hemodynamic load imposed by the fistula are discussed. This procedure may be, to date, the most effective method for diminishing the disparity between the lengths of two limbs. In a child with a normal heart the creation of such a fistula may impose no cardiac hazard. However, in some children, especially those with cardiac disease, there may be serious cardiovascular consequences. This procedure requires at all stages the close collaboration of the orthopedic surgeon, the vascular surgeon, and the cardiologist.
D-Serine regulates cerebellar LTD and motor coordination through the δ2 glutamate receptor
Authors: Wataru Kakegawa, Yurika Miyoshi, Kenji Hamase, Shinji Matsuda, Keiko Matsuda, Kazuhisa Kohda, Kyoichi Emi, Junko Motohashi, Ryuichi Konno, Kiyoshi Zaitsu, Michisuke Yuzaki
Journal: Nature Neuroscience (2011)
Health aid is not distributed according to need, WHO says
Authors: R. Dobson
Journal: BMJ (2009)

A new report from the World Health Organization points to big differences in the amount of healthcare aid provided to different countries that are not related to levels of need.

The report says that major imbalances in the allocation of health aid run counter to internationally recognised principles of effective aid ( Bulletin of the World Health Organization doi:10.2471/BLT.08.058677). 

“There are some marked imbalances in the allocation of health aid . . . Countries with comparable levels of poverty and health-related needs receive remarkably different levels of aid,” warn the report’s authors. …