Computed Tomography in Cerebral Malignant Disease
Authors: James B. Reuler, Donald E. Girard, David A. Nardone
Journal: Annals of Internal Medicine (1979)

Letters and Corrections1 November 1979Computed Tomography in Cerebral Malignant DiseaseJAMES B. REULER, M.D., DONALD E. GIRARD, M.D., DAVID A. NARDONE, M.D.JAMES B. REULER, M.D.Search for more papers by this author, DONALD E. GIRARD, M.D.Search for more papers by this author, DAVID A. NARDONE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-91-5-797_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: In Dr. Weisberg's recent comprehensive review of computed tomography (CT)(1), two areas were not addressed in regard to malignant disease—leptomeningeal carcinomatosis and progressive multifocal leukoencephalopathy. Both may mimic neurologic disorders and are frequently difficult diagnoses to establish (2-5).There is little in the literature on the usefulness of CT scanning in diagnosing leptomeningeal carcinomatosis, but a recent report noted that computed tomography detected intracranial meningeal spread in 44% of these patients (6). The characteristic finding was subarachnoid contrast enhancement, and in two patients this finding was the first suggestion of the process.Progressive multifocal leukoencephalopathy is a...References1. WEISBERG L. Computed tomography in the diagnosis of intracranial disease. Ann Intern Med. 1979;91:87-105. LinkGoogle Scholar2. LITTLEDALEOKAZAK JAH. Meningeal carcinomatosis. Arch Neurol. 1974;30:138-43. CrossrefMedlineGoogle Scholar3. OLSONCHERNIKPOSNER MNJ. Infiltration of the leptomeninges by systemic cancer. Arch Neurol. 1974;30:122-37. CrossrefMedlineGoogle Scholar4. RICHARDSON E. Our evolving understanding of progressive multifocal leukoencephalopathy. Ann NY Acad Sci. 1974;230:358-64. CrossrefMedlineGoogle Scholar5. REULERMEIER JD. Leptomeningeal carcinomatosis with normal CSF features. Arch Intern Med. 1979;139:237-8. CrossrefMedlineGoogle Scholar6. ENZMANNKRIKORIANYORKEHAYWARD DJCR. Computed tomography in leptomeningeal spread of tumor. J Comput Assist Tomogr. 1978;2:448-55. CrossrefMedlineGoogle Scholar7. CARROLLLANENORMANENZMANN BBDD. Diagnosis of progressive multifocal leukoencephalopathy by computed tomography. Radiology. 1977;122:137-41. CrossrefMedlineGoogle Scholar8. CONOMYWEINSTEINAGAMANOLISHOLT JMDW. Computed tomography in progressive multifocal leukoencephalopathy. AJR. 1976;127:663-5. CrossrefMedlineGoogle Scholar1. ENZMANNKRIKORIANYORKEHAYWARD DJCR. Computed tomography in leptomeningeal spread of tumor. J Comput Assist Tomogr. 1978;2:448-55. CrossrefMedlineGoogle Scholar2. HEINZDRAYERHAGENGELL EBC. Computed tomography in white matter disease. Radiology. 1979;130:371-8. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Veterans Administration Hospital Portland, OR 97201 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByProgressive multifocal leukoencephalopathy: Clinical and radiographic features 1 November 1979Volume 91, Issue 5Page: 797-797KeywordsCarcinomatosisComputed axial tomographyProgressive multifocal leukoencephalopathySubarachnoid hemorrhage Issue Published: 1 November 1979 PDF DownloadLoading ...