Transfusion of Blood Components from a Donor with Human T-Lymphotropic Virus Type II (HTLV-II) Infection
Authors: Elizabeth Donegan
Journal: Annals of Internal Medicine (1990)

Brief Reports1 October 1990Transfusion of Blood Components from a Donor with Human T-Lymphotropic Virus Type II (HTLV-II) InfectionElizabeth Donegan, MD, Michael P. Busch, MD, PhD, Janice A. Galleshaw, MD, George M. Shaw, MD, PhD, James W. Mosley, MD, Transfusion Safety Study GroupElizabeth Donegan, MDSearch for more papers by this author, Michael P. Busch, MD, PhDSearch for more papers by this author, Janice A. Galleshaw, MDSearch for more papers by this author, George M. Shaw, MD, PhDSearch for more papers by this author, James W. Mosley, MDSearch for more papers by this author, Transfusion Safety Study GroupSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-113-7-555 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptHuman T-lymphotropic virus type I (HTLV-I) is an etiologic agent of adult T-cell leukemia and of spastic myelopathy. Type II virus (HTLV-II) has been recovered from three patients with hairy cell leukemia and from one with exfoliative erythroderma (1-3), but the lack of evidence that HTLV-II infection is associated with other diseases is not necessarily meaningful because generally available serologic tests do not distinguish between HTLV-I and HTLV-II (4). The knowledge that HTLV-I can be transmitted by transfusion (5) prompted routine blood-donor screening in the United States and notification of past recipients of blood from positive donors (6, 7).The...References1. Sohn C, Blayney D, and Misset J. Leukopenie chronic T cell leukemia mimicking hairy cell leukemia: association with human retroviruses. Blood. 1986;67:949-56. CrossrefMedlineGoogle Scholar2. Rosenblatt J, Gasson J, and Glaspy J. Relationship between human T cell leukemia virus-II and atypical hairy cell leukemia: a serologic study of hairy cell leukemia patients. Leukemia. 1987;1: 397-401. MedlineGoogle Scholar3. Ehrlich G, Glaser J, and LaVigne K. Prevalence of human T-cell leukemia/lymphoma virus (HTLV) type II infection among high-risk individuals: type-specific identification of HTLVs by polymerase chain reaction. Blood. 1989;74:1658-64. CrossrefMedlineGoogle Scholar4. Licensure of screening tests for antibody to human T-lymphotropic virus type I. MMWR. 1988;37:736-47. MedlineGoogle Scholar5. Okochi K, Sato H, and Hinuma Y. A retrospective study on transmission of adult T cell leukemia virus by blood transfusion: seroconversion in recipients. Vox Sang. 1984;46:245-53. CrossrefMedlineGoogle Scholar6. Interim guidelines for testing donated blood for HTLV-I antibodies. Memorandum 88-5. Arlington, Virginia: American Association of Blood Banks; 1988. Google Scholar7. Guidelines for notification and counseling of recipients of HTLV-I/II positive blood. Memorandum 89-4. Arlington, Virginia: American Association of Blood Banks; 1989. Google Scholar8. Lipka J, Bui K, and Reyes G. Determination of a unique and immunodominant epitope of HTLV-I. J Infect Dis. [In press]. Google Scholar9. Manns A, Murphy E, and Wilks R. Transfusion transmission of HTLV-I: seroconversion in a prospective cohort of recipients. Blood. 1989;72(Suppl):356a. Google Scholar10. Operskalski E, Schiff E, and Kleinman S. Epidemiologic background of blood donors with antibody to human T-cell lymphotropic virus. Transfusion. 1989;29:746-8. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: Elizabeth Donegan, MD; Michael P. Busch, MD, PhD; Janice A. Galleshaw, MD; George M. Shaw, MD, PhD; James W. Mosley, MDFrom the University of California, San Francisco, and Irwin Memorial Blood Center, San Francisco, California; the University of Alabama at Birmingham, Birmingham, Alabama; and the University of Southern California, Los Angeles, California.*Members of the Transfusion Safety Study Group are listed in the Acknowledgments section at the end of text. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byTransfusion‐Transmitted DiseasesTransfusion-Transmitted DiseasesHuman Lymphotropic Viruses: HTLV-1 and HTLV-2Infection with human T-lymphotropic virus types-1 and -2 (HTLV-1 and -2): Implications for blood transfusion safetyConcomitant Infections with Human Immunodeficiency Virus Type 1 and Human T-Lymphotropic Virus Types 1 and 2Human T-Cell Leukemia Virus Type 1: Epidemiology and Clinical Features of Related CancerTransfusion-transmitted human T-lymphotropic virus Type I infection in a United States military emergency whole blood transfusion recipient in Afghanistan, 2010Transfusion‐Transmitted DiseasesEpidemiology, Treatment, and Prevention of Human T-Cell Leukemia Virus Type 1-Associated DiseasesHuman Lymphotropic Viruses: HTLV?1 and HTLV?2Blood safety strategies for human T-cell lymphotropic virus in EuropeTransmission of Tropical and Geographically Restricted Infections during Solid-Organ TransplantationHigh Seroprevalence of Anti-HTLV-I/II Antibodies Among Solid Organ Donors Necessitates Confirmatory TestingGlobal epidemiology of HTLV-I infection and associated diseasesHuman T-lymphotropic virus type II and neurological diseaseRetroviruses—Human T-Cell Lymphotropic VirusHuman T Lymphotropic Virus Type II (HTLV-II): Epidemiology, Molecular Properties, and Clinical Features of InfectionReduction of HTLV-I-infected cells in blood by leukocyte filtrationThe Epidemiology of Human T-lymphotropic Virus Types I and IINew Testing Approaches in Transfusion MedicineBlood-borne Infections Associated with TransfusionEvidence for Sexual Transmission of Human T Lymphotropic Virus Type IIBrian Hjelle, MD, S. Cyrus, MT (SBB), S. G. Swenson, MT (SBB)Detection of Human T-cell Leukemia VirusesThe Significance of T Lymphocytes in Transfusion MedicineComplications related to intraoperative blood component therapy 1 October 1990Volume 113, Issue 7Page: 555-556KeywordsBlood banksBlood transfusionHeartHIV infectionsHuman t lymphotropic virusInfectious diseasesLungsMyelopathyResearch laboratoriesSafety studies ePublished: 1 December 2008 Issue Published: 1 October 1990 PDF downloadLoading ...