tbuckley/cabot-search huggingface dataset:
THE AETIOLOGY OF SEBORRHCEIC DERMATITIS.*
Authors: G. B. DOWLING
Journal: British Journal of Dermatology (1939)

Journal Article THE ÆTIOLOGY OF SEBORRHCEIC DERMATITIS. Get access G. B. DOWLING, M.D., F.R.C.P. G. B. DOWLING, M.D., F.R.C.P. Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology and Syphilis, Volume 51, Issue 1, 1 January 1939, Pages 1–7, https://doi.org/10.1111/j.1365-2133.1939.tb10599.x Published: 01 January 1939
Disorders of Taste and Smell
Authors: R. I. Henkin
Journal: JAMA (1971)

<h3>To the Editor.—</h3> The term cacosmia used to describe the olfactory symptoms experienced and reported by Romberg (<b>218</b>:596, 1971) following an upper respiratory tract infection is indeed apt. His description of the term dysosmia as "a very mild descriptive term" is, however, not necessarily syntactically correct. We have also been concerned about the inadequacy and apparent redundancy of terms used to describe alterations of taste and olfaction. Careful evaluation of the symptoms of approximately 400 patients with disorders of these two senses have taught us that there are several different aspects of altered taste and smell acuity. With these differences in mind we have proposed the following general and specific terms to describe the pathological alterations we have observed.<sup>1</sup> <i>Dysgeusia</i>(dys—bad, disordered + geusis—taste): a general term describing any distortion of normal taste perception. <i>Cacogeusia</i>(caco—bad, ill): a specific term describing the abhorent, obnoxious taste produced by the introduction
Whipple’s Disease: Magnification Endoscopy and Histological Characteristics
Authors: S. Kolfenbach, K. Mönkemüller, C. Röcken, P. Malfertheiner
Journal: Endoscopy (2008)

Figure 1 A 51-year-old man presented with polyarthralgia and weight loss of 35 kg over an 18-month period. He had also developed mental status changes. Computed tomography demonstrated intracerebral abscesses. On esophagogastroduodenoscopy, the duodenal mucosa showed nonspecific duodenitis. The mucosa was slightly erythematous and edematous. Using magnification endoscopy (Olympus, Hamburg; original magnification × 115), the duodenal villi were clearly evaluated. These appeared edematous and slightly flattened, with multiple yellow spots representing engorged lymphatic vessels.
Correlation between carbon dioxide retention during exercise and the rate of decline of FEV1 in cystic fibrosis
Authors: D Wat
Journal: Thorax (2005)

▴ Javadpour SM, Selvadurai H, Wilkes DL, et al. Does carbon dioxide retention during exercise predict a more rapid decline in FEV1 in cystic fibrosis? Arch Dis Child2005;90:792–5. [OpenUrl][1][Abstract/FREE Full Text][2] Progressive decline in lung function is an important cause of morbidity and mortality in patients with cystic fibrosis (CF). Markers to identify the patients at risk of rapid decline in their clinical condition are lacking. No study to date has used carbon dioxide (CO2) retention during exercise to predict the rate of decline in respiratory function in CF. … [1]: {openurl}?query=rft.jtitle%253DArchives%2Bof%2BDisease%2Bin%2BChildhood%26rft.stitle%253DArch.%2BDis.%2BChild.%26rft.issn%253D0003-9888%26rft.aulast%253DJavadpour%26rft.auinit1%253DS%2BM%26rft.volume%253D90%26rft.issue%253D8%26rft.spage%253D792%26rft.epage%253D795%26rft.atitle%253DDoes%2Bcarbon%2Bdioxide%2Bretention%2Bduring%2Bexercise%2Bpredict%2Ba%2Bmore%2Brapid%2Bdecline%2Bin%2BFEV1%2Bin%2Bcystic%2Bfibrosis%253F%26rft_id%253Dinfo%253Adoi%252F10.1136%252Fadc.2004.070110%26rft_id%253Dinfo%253Apmid%252F16040875%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/ijlink?linkType=ABST&journalCode=archdischild&resid=90/8/792&atom=%2Fthoraxjnl%2F60%2F12%2F1011.atom
Davidson's Principles and Practice of Medicine
Authors: S. L. Shumak
Journal: JAMA (2004)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Questionnaire surveys: sources of bias
Authors: P. Sedgwick
Journal: BMJ (2013)

<h3>Abstract</h3> Intracranial neurophysiological recordings require chronic implants to provide transcranial access to the brain. Especially in larger animals, which participate in experiments over extended periods of time, implants should match the skull curvature to promote osseointegration and avoid tissue and bacterial ingress over time. Proposed CAD methods for designing implants to date have focused on naive animals with continuous and even skull surfaces and calculate Boolean differences between implant and skull surface to fit the implant to the skull curvature. However, custom-fitting by calculating the difference fails, if a discontinuous skull surface needs to be matched. Also, the difference method does not allow designs with constant material thickness along the skull curvature, e.g., to allow fixed screw lengths. We present a universal step-by-step guide for custom-fitting implants which overcomes these limitations. It is suited for unusual skull conditions, like surface discontinuities or irregularities and includes virtual bending as a process to match skull surfaces while maintaining implant thickness. We demonstrate its applicability for a wide spectrum of scenarios, ranging from complex-shaped single-pieced implants to detailed multicomponent implant systems built on even or discontinuous skull. The guide uses only a few software tools and the final virtual product can be manufactured using CNC milling or 3D printing. A detailed description of this process is available on GitHub including step-by-step video instructions suitable for users without any prior knowledge in CAD programming. We report the experience with these implants over several years in 11 rhesus monkeys.
Multidrug-resistant bacteria colonization amongst patients newly admitted to a geriatric unit: A prospective cohort study
Authors: Didier Schoevaerdts, Alexia Verroken, Te-Din Huang, Malorie Frennet, Catherine Berhin, Jacques Jamart, Pierre Bogaerts, Christian Swine, Youri Glupczynski
Journal: Journal of Infection (2012)
The Drug Treatment of Anxiety
Authors: Jerrold F. Rosenbaum
Journal: New England Journal of Medicine (1982)

ANXIETY is the distressing experience of dread and foreboding, with an array of autonomic concomitants (Table 1). The therapeutic benefits obtained from antianxiety medication, weighed against the adverse effects, have been a matter of considerable public controversy. Although lay media and Senate hearings have decried benzodiazepines as rampantly overprescribed and dangerous, offering dramatic individual cases of iatrogenous toxicity, more rigorous and extensive surveys have concluded that reckless overprescribing is rare and that these agents are relatively safe.1 , 2 In 1979, over 60 million prescriptions were filled in the United States for benzodiazepines, perennially among the nation's most prescribed drugs. The attitudes . . .
466 NATREMIA AND CHILD-TURCOTTE-PUGH (CTP) SCORE MAY IMPROVE THE SELECTION OF CANDIDATES FOR LIVER TRANSPLANTATION (LT) WITH LOW MODEL FOR END-STAGE LIVER DISEASE SCORE (MELD)
Authors: S. Gitto, M. Biselli, A. Gramenzi, G. Vitale, S. Lorenzini, R. Di Donato, L. Brodosi, M.C. Morelli, G.L. Grazi, A.D. Pinna, M. Bernardi, P. Andreone, Bologna Liver Transplantation Group (BLTG)
Journal: Journal of Hepatology (2009)
A Clinical Screening Tool Identifies Autoimmune Diabetes in Adults
Authors: Timothy M.E. Davis, Carole A. Cull, Rury R. Holman
Journal: Diabetes Care (2006)

Fourlanos et al. (1) report on a screening instrument designed to facilitate management of latent autoimmune diabetes of adults (LADA). They assert that in poorly controlled type 2 patients exhibiting two or more of five features (age <50 years, hyperglycemic symptoms, BMI <25.0 kg/m2, and personal and family history of autoimmunity), the “logical ” next step is confirmatory islet antibody testing (1).

Although the effect of routine use of the instrument on outcomes such as HbA …
Management of Patients With Heart Disease for Noncardiac Surgery
Authors: John H. Tinker
Journal: JAMA (1981)

PHYSICIANS are frequently consulted about the advisability and perioperative management of noncardiac surgery in patients with heart disease. The risks in patients with coronary artery disease have been extensively studied, whereas other types of heart disease, perhaps because of their more uniformly progressive nature, have not proved as amenable to specific risk analysis. Clinical judgment remains central to the assessment of the risk-benefit ratio of any proposed procedure. We intend to present briefly considerations of risk, preoperative pharmacologic management, and a discussion of basic principles of operative and postoperative care. <h3>Risk of Noncardiac Surgery in Patients With Coronary Artery Disease</h3><h3>Prior Myocardial Infarction.—</h3> Several retrospective studies have shown that patients with a prior myocardial infarction (MI) have about a 6% incidence of new infarction occurring within seven days of anesthesia and surgery, unless the prior MI was recent.<sup>1-3</sup>Operations performed within three months of an MI are associated with
Combined vasopressin, steroids, and epinephrine improved survival in in-hospital cardiac arrest
Authors: Kenneth A. Ballew
Journal: Annals of Internal Medicine (2013)

Source Citation Mentzelopoulos SD, Malachias S, Chamos C, et al. Vasopressin, steroids, and epinephrine and neurologically favorable survival after in-hospital cardiac arrest: a randomized clinical trial. JAMA. 2013;310:270-9. 23860985
TCT-312 Coronary Plaque Regression by 64-Slice Computed Tomography Coronary Angiography (CTCA): Pipe Dream or Real Possibility
Authors: Norman Lepor, Laurn Contreras, Philip Bretsky, Gerald Friede, Joel Freedman, Ivor Geft, Hooman Madyoon
Journal: Journal of the American College of Cardiology (2012)
Underdosing the antidote for acetaminophen
Authors: A. Anker
Journal: JAMA (1993)

To the Editor.  —We would like to inform your readers of a disturbing pattern in the treatment of acetaminophen overdoses.  Oregon Poison Center serves a population of 2.5 million people and, like all poison centers, it frequently deals with acetaminophen overdoses. In the last 6 months we have noted three instances in which physicians treating patients with acetaminophen overdoses discontinued acetylcysteine therapy on the basis of serial acetaminophen assays and did not complete the standard course of treatment. When questioned, they stated that the package insert recommended cessation of acetylcysteine therapy when acetaminophen levels were no longer detectable. We believe that this potentially dangerous practice is the result of ambiguous wording.  outcomes for these patients are unknown because after hospital discharge they were not available for follow-up.   package inserts for at least two available acetylcysteine preparations (Mucosil and Mucomyst) state: The maintenance dose is then repeated at
Thyroid toxicants: assessing reproductive health effects.
Authors: Gloria D Jahnke, Neepa Y Choksi, John A Moore, Michael D Shelby
Journal: Environmental Health Perspectives (2003)

A thyroid toxicant workshop sponsored by the National Toxicology Program Center for the Evaluation of Risks to Human Reproduction convened on 28-29 April 2003 in Alexandria, Virginia. The purpose of this workshop was to examine and discuss chemical-induced thyroid dysfunction in experimental animals and the relevance of reproductive and developmental effects observed for prediction of adverse effects in humans. Presentations highlighted and compared reproductive and developmental effects of thyroid hormones in humans and rodents. Rodent models of thyroid system dysfunction were presented. Animal testing protocols were reviewed, taking into account protocol designs that allow extrapolation to possible human health effects. Potential screening methods to assess toxicant-induced thyroid dysfunction were outlined, and postnatal bioassays of thyroid-related effects were discussed.
Time to Junk Junk Latin?
Authors: JAMES O. MORSE
Journal: Annals of Internal Medicine (1980)

Letters and Corrections1 May 1980Time to Junk Junk Latin?JAMES O. MORSE, M.D.JAMES O. MORSE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-92-5-722_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: The correction needed for a recent article in your journal (1) in which the dose of amphotericin, intended to be printed as 40 mg every other day, was transformed into 40 mg four times a day would have been unnecessary were such a hybrid abbreviation as "q.o.d." avoided in physicians' orders and other medical writing. All other commonly used abbreviations designating dosage intervals refer to a legitimate Latin phrase: q.d. or qq.d. (quaque die) or o.d. (omni die) for daily; q.i.d. (quater in die) for four times a day. "Q.o.d." appears to be an attempt to insert...Reference1. ADELMAN B. Correction: Dose of amphotericin B. Ann Intern Med. 1979;91:798. Letter. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: JAMES O. MORSE, M.D. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 May 1980Volume 92, Issue 5Page: 722-723KeywordsAmphotericin ePublished: 1 December 2008 Issue Published: 1 May 1980 PDF downloadLoading ...
Effect of phalloidin on cholestasis, hemodynamics, and microcirculation in isolated perfused rat liver
Authors: C Barriault, J Petit, M Gascon-Barre, P Huet, I M Yousef, B Tuchweber
Journal: Hepatology (1996)

In this study, the possible role of the hepatic microcirculation in phalloidin-induced cholestasis and hepatotoxicity was examined in isolated perfused rat livers (IPRL). Administration of a phalloidin bolus (1 mg/kg body weight) through the portal vein induced an immediate reduction of bile flow. In 16.9 minutes, bile flow was 50% lower than basal values. Portal pressure was only increased in 60 minutes after phalloidin injection and increased sharply from this time up to the end of perfusion (90 minutes). Under these conditions, phalloidin did not induce liver cell cytolysis, as assessed by aspartate transaminase (AST) and lactate dehydrogenase (LDH) release in the perfusate effluent. Under electron microscopy, hepatocytic vacuolization was mild 15 minutes after phalloidin administration but increased with time. At the end of perfusion, the hepatic architecture was markedly altered; erythrocyte accumulation was observed in both sinusoids and hepatocyte vacuoles. Evaluation by multiple indicator dilution curves showed that extravascular volume (EVV) was significantly affected by phalloidin. It was augmented in 30 minutes after phalloidin administration with values increasing gradually over time. Neither vascular nor cellular volume was altered. The hepatic swelling may be attributed to enlargement of the extravascular space of the liver. These results indicate that changes in the liver microcirculation are not the primary cause of phalloidin-induced cholestasis in the IPRL.
ANGIOMA-MYXO-SARCOMA OF THE ORBIT, WITH REPORT OF A CASE.
Authors: J. C. AYRES
Journal: JAMA (1898)

There is no locality of its size in the human body so rich in the various tissues which may serve as the starting point for the development of tumors, both malignant and benign, of the orbit. In it we have bone, periosteum, muscular tissue, fat, fibrous and connective tissue, glands and mucous membrane, and in the capsule of Tenon a serous cavity lined with a serous membrane. There is also the optic nerve and a liberal supply of blood vessels. Among the malignant tumors we find carcinoma, sarcoma, myo-sarcoma, and from the internal ocular tunics, melano-sarcoma and glioma. Among the benign tumors we find angioma, erectile tumors, fibroma, myxoma, lipoma, hydatids, serous and bloody cysts, dermoids, osteomata, papillomata, cysticerci and occasionally enchondroma. There are also tumors of the lachrymal gland and optic nerve, and aneurysms of the ophthalmic artery, both traumatic and idiopathic. The orbit is occasionally involved by disease
The Hepatotoxicity of Intravenous Aureomycin
Authors: A. M. Rutenburg, S. Pinkes
Journal: New England Journal of Medicine (1952)

THIS report deals with hyperbilirubinemia developing during the intravenous administration of aureomycin in a series of 39 patients. To determine the relation of intravenously administered therapeutic doses of aureomycin to this disorder the effect of the drug on normal liver function was studied in 20 selected patients with no evidence of cardiovascular, renal, hepatic or biliary-tract disease. Each patient received aureomycin (500 mg. of the hydrochloride buffered with sodium glycinate, dissolved in 500 cc. of isotonic sodium chloride) intravenously twice a day for three consecutive days. Serum bilirubin§ and urinary urobilinogen§ excretion were determined in all 20 patients. Serum bilirubin . . .
Subclavian Venous Stenosis
Authors: Diane Davis
Journal: JAMA (1984)

Subclavian hemodialysis catheters are widely employed for temporary hemodialysis access, but there are few reports of serious complications. We report three cases in which the prolonged (&gt;15 days) use of subclavian dialysis catheters ipsilateral to the permanent vascular access was associated with the development of subclavian vein (SCV) stenosis three to six months after the temporary catheter was removed. In one case, the use of the permanent access was severely limited by massive arm edema. We conclude that, in addition to the usual complications of SCV cannulation, long-term use of SCV hemodialysis catheters can be associated with major late obstructive complications that may compromise permanent vascular access. We recommend that, wherever possible, temporary dialysis catheters and other subclavian lines be placed contralateral to the permanent vascular access site in patients undergoing hemodialysis. (<i>JAMA</i>1984;252:3404-3406)
Primary Immunodeficiencies in Brazilian patients younger than five years old
Authors: M.B. Dorna, L.A. Watanabe, A.B.F. Fomin, A.C. Pastorino, C.M.A. Jacob, C.A.A. Silva, D.M. Vasconcelos, M.M.S. Carneiro-Sampaio
Journal: Journal of Allergy and Clinical Immunology (2011)
Exchangeable Sodium, Body Potassium, and Body Water in Previously Edematous Cardiac Patients
Authors: HUGH J. CARROLL, RITA GOTTERER, BERNARD ALTSHULER
Journal: Circulation (1965)

Measurements have been made of total exchangeable sodium, total body potassium, and total body water in a group of 13 previously edematous patients with heart disease, and in 20 "control" patients. The data show that while both groups have the same quantity of water as the per cent of body weight and the same body potassium concentration, the cardiac group has an excess of exchangeable sodium when compared with the "controls." Since the excess sodium in the cardiac group cannot be attributed to the loss of potassium or the accumulation of water, the results of these studies are taken as evidence that osmotic inactivation of a considerable amount of some cation, probably sodium, has taken place. It is suggested that a likely site for cation binding is in the polyanionic constituents of the connective tissues.
Abstract 81: Rapamycin increases radiosensitivity of cancer cells by induction of premature senescence.
Authors: Hae Yun Nam, Myung Woul Han, Hyo Won Chang, Yoon Sun Lee, Myungjin Lee, Mi Ra Kim, Hyang Ju Lee, Ji Yung Jeoung, So Young Moon, Hyo Jung Kim, Sang Yoon Kim, Seong Who Kim
Journal: Cancer Research (2013)

Abstract Autophagy is frequently activated in radioresistant cancer cells. Rapamycin, mammalian target of rapamycin (mTOR) inhibitor, activates autophagy but enhances radiosensitivity. The mechanism of these actions by which such opposing functions coexist was investigated on radiation-resistant cancer cell lines (AMC-HN-9 and U-87) and the antitumor activity was evaluated in mice bearing xenografts of the cancer cells. Enhanced autophagic flux induced by radiation returned to untreated control levels. Treatment of the cancer cells with rapamycin leads to the potentiation and prolongation of radiation-induced autophagy, the increases in senescence-associated β-galactosidase activity, heterochromatin formation, and irreversible growth arrest. Furthermore, rapamycine resulted in a tumor regrowth delay and increased the level of β-galactosidase staining and the expression of heterochromatin markers in irradiated xenografts. These results suggest that even though autophagy is a survival mechanism in radioresistant cells, a persistent activation of autophagy by mTOR inhibitor induces premature senescence in these cells, eventually making the cells radiosensitive. Our data suggest a novel mechanism by which an inhibition of mTOR pathway increases autophagy but paradoxically increases radiosensitivity in radioresistant cancer cells. Citation Format: Hae Yun Nam, Myung Woul Han, Hyo Won Chang, Yoon Sun Lee, Myungjin Lee, Mi Ra Kim, Hyang Ju Lee, Ji Yung Jeoung, So Young Moon, Hyo Jung Kim, Sang Yoon Kim, Seong Who Kim. Rapamycin increases radiosensitivity of cancer cells by induction of premature senescence. [abstract]. In: Proceedings of the 104th Annual Meeting of the American Association for Cancer Research; 2013 Apr 6-10; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2013;73(8 Suppl):Abstract nr 81. doi:10.1158/1538-7445.AM2013-81
Lipoxygenase inhibitors: A comparative QSAR study review and evaluation of new QSARs
Authors: Eleni Pontiki, Dimitra Hadjipavlou‐Litina
Journal: Medicinal Research Reviews (2006)

Abstract This paper contains a quantitative structure activity relationship (QSAR) study for lipoxygenase (LO) inhibitors. It reveals that in almost all cases, the clog P parameter plays an important part in the QSARs (linear or bilinear model). In some cases the steric factors such as the overall molar refractivity (CMR) or the substituents molar refractivity (MR) (linear or parabola) are important. Electronic effects are comparatively unimportant. The study shows that log P as calculated from the Clog P program is suitable for this form of QSAR study. © 2006 Wiley Periodicals, Inc. Med Res Rev, 28, No. 1, 39–117, 2008