Evaluation of Renal Function Without Collection of Urine
Authors: M. H. GAULT
Journal: Annals of Internal Medicine (1968)

Editorials1 December 1968Evaluation of Renal Function Without Collection of UrineM. H. GAULT, J. B. DOSSETORM. H. GAULTSearch for more papers by this author, J. B. DOSSETORSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-69-6-1326 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptMany studies during the last 20 years have proposed methods for quantitative evaluation of renal excretory function without periods of constant infusion or collection of urine with its frequent errors. The methods may be clasified in two groups: [1] measurement of the concentration of some natural substance in blood which is retained in increasing concentration as renal function declines, such as urea or creatinine; [2] measurement of the rate of disappearance from plasma of some injected substance that is normally excreted rapidly by glomerular filtration or tubular secretion (1-4). The disappearance rate may be determined by analysis of serial blood...References1. GAULT MH: The plasma phenolsulfonphthalein index (PSPI) of renal function. I. Theoretical considerations and investigative studies. Canad. Med. Ass. J. 94: 61, 1966. MedlineGoogle Scholar2. SMITH HW: The Kidney. Structure and Function in Health and Disease. The Oxford University Press, London, 1951, p. 57. Google Scholar3. Editorial: Measurement of glomerular filtration rate. Lancet 2: 276, 1965. MedlineGoogle Scholar4. BLAUFOXMERRILL MDJP: Simplified hippuran clearance. Measurement of renal function in man with simplified hippuran clearances. Nephron 3: 274, 1966. CrossrefMedlineGoogle Scholar5. SHERWOODFREEMANJOEKES TTAM: The clinical "renogram" as a guide to renal function. Brit. J. Radiol. 37: 645, 1964. CrossrefMedlineGoogle Scholar6. HÖFFLEROFFERMANNFRENZ DAH: The intravenous phenol-red (PSP) test. I. Principles of method and normal values. German Med. Monthly 13: 281, 1968. [Deutsch. Med. Woschr. 93: 397, 1968.] MedlineGoogle Scholar7. HÖFFLEROFFERMANNFRENZ DAH: The intravenous PSP (Phenol-red) test. II. Clinical applications and interpretation. German Med. Monthly 13: 286, 1968. [Deutsch. Med. Woschr. 93: 443, 1968.] MedlineGoogle Scholar8. EDWARDSWHYTE KDHM: Plasma creatinine level and creatinine clearance as tests of renal function. Australasian Ann. Med. 8: 218, 1959. CrossrefMedlineGoogle Scholar9. GAULTDOSSETOR MHJB: The place of phenolsulfonphthalein (PSP) in the measurement of renal function. Amer. Heart J. 75: 723, 1968. CrossrefMedlineGoogle Scholar10. HEALY JK: Clinical assessment of glomerular filtration rate by different forms of creatinine clearance and a modified urinary phenolsulphonphthalein excretion test. Amer. J. Med. 44: 348, 1968. CrossrefMedlineGoogle Scholar11. DOSSETOR JB: Creatinemia versus uremia. The relative significance of blood urea nitrogen and serum creatinine concentrations in azotemia. Ann. Intern. Med. 65: 1287, 1966. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: McGill University Montreal, Canada PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByValidation of estimated renal function measurements compared with the isotopic glomerular filtration rate in an HIV-infected cohort 1 December 1968Volume 69, Issue 6Page: 1326-1328KeywordsAttentionBloodBlood plasmaCreatinineUreaUrine Issue Published: 1 December 1968 PDF DownloadLoading ...