AN ARTICLE CONTRIBUTED TO AN ANNIVERSARY VOLUME IN HONOR OF DOCTOR JOSEPH HERSEY PRATT
Authors: G. P. GRABFIELD
Journal: Annals of Internal Medicine (1937)

Article1 October 1937AN ARTICLE CONTRIBUTED TO AN ANNIVERSARY VOLUME IN HONOR OF DOCTOR JOSEPH HERSEY PRATTA PHARMACOLOGIC STUDY OF THE MECHANISM OF GOUT*G. P. GRABFIELD, F.A.C.P.G. P. GRABFIELD, F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-11-4-651 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptDr. Pratt's long interest in and contributions to the subject of gout make it a particularly appropriate subject for his birthday volume. It is especially fitting that these observations be reported here since they had their inception in a research the author was privileged to share with Dr. Pratt.1In these experiments we concluded that the action of cinchophen on uric acid excretion was exerted through the central nervous system. At that time methods for testing this suggestion were wanting. With the development of new methods it became possible to test this hypothesis in the experimental animal. In the last...Bibliography1. GRABFIELDPRATT GPJH: Action of cinchophen, Jr. Pharmacol. and Exper. Therap., 1931, xlii, 407. Google Scholar2. THANNHAUSER SJ: Lehrbuch des Stoffwechsels und der Stoffwechselkrankheiten, 1929, Bergmann, Munich. CrossrefGoogle Scholar3. SCHNITKERRICHTER MAAB: Nephritis in gout, Am. Jr. Med. Sci., 1936, cxcii, 241. CrossrefGoogle Scholar4. ELLINGERHIRT PA: Zur Funktion der Nierennerven, Arch. f. exper. Path. u. Pharmacol., 1925, cvi, 10. Google Scholar5. MARSHALLKOLLS EKAC: Studies on nervous control of the kidney in relation to diuresis and urinary secretion, Am. Jr. Physiol., 1919, xlix, 302, 317, 326, 335, 339. CrossrefGoogle Scholar6. LARSON HW: Colorimetric method for determination of allantoin, Jr. Biol. Chem., 1932, xciv, 727. CrossrefGoogle Scholar7. GRABFIELDGRAY GPMG: Action of cinchophen on uric acid and allantoin excretion in dogs, and its effect on nitrogen and sulphur excretion, Jr. Pharmacol. and Exper. Therap., 1934, l, 123. Google Scholar8. QUINBY WC: The function of the kidney when deprived of its nerves, Jr. Exper. Med., 1916, xxiii, 535. CrossrefGoogle Scholar9. FISCHER K: Anatomie und Physiologie der Nervi proprii der Nierenkapsel und ihre Bedeutung für die Nierenchirurgie, insbesondere für die Wirkingweise der Nierenentkapselung, Deutsch. Ztschr. f. Chir., 1930, ccxxii, 228. CrossrefGoogle Scholar10. FELDBERGGADDUM WJH: Chemical transmitter at synapses in sympathetic ganglion, Jr. Physiol., 1934, lxxi, 305. CrossrefGoogle Scholar11. GRABFIELDPRESCOTTSWAN GPBWK: The effect of ergotamine and atropine on the uricosuric action of cinchophen. To appear in Jr. Pharmacol. and Exper. Therap., 1937. Google Scholar12. HARPUDER K: Pharmakologische Beeinflussung des Purinstoffwechsels beim Menschen, Ztschr. f. d. ges. exper. Med., 1924, lxii, 1. CrossrefGoogle Scholar13. HENCH PS: Proc. Staff Meet. Mayo Clinic, 1937. Google Scholar14. TALBOTTJACOBSONOBERG JHBMSA: The electrolyte balance in acute gout, Jr. Clin. Invest. 1935, xiv, 411. CrossrefGoogle Scholar15. LOEWENHARDT FE: Gout and the kidneys, Klin. Wchnschr., 1922, i, 2319. CrossrefGoogle Scholar16. BRUGSCH T: Gout Question, Med. Klin., 1922, xviii, 553. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: G. P. GRABFIELD, F.A.C.P.Affiliations: Boston, Massachusetts*Received for publication August 5, 1937.From the Medical Clinic of the Peter Bent Brigham Hospital and the Department of Pharmacology of the Harvard Medical School. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDie GichtPharmakologie und vegetatives NervensystemStoffwechsel und vegetatives NervensystemDie GichtRecent Researches on Arthritis and Rheumatism in the United StatesTHE PROBLEM OF RHEUMATISM AND ARTHRITIS REVIEW OF AMERICAN AND ENGLISH LITERATURE FOR 1937 (Fifth Rheumatism Review)*PHILIP S. HENCH, M.D., F.A.C.P., WALTER BAUER, M.D., F.A.C.P., M. HENRY DAWSON, M.D., FRANCIS HALL, M.D., F.A.C.P., W. PAUL HOLBROOK, M.D., F.A.C.P., J. ALBERT KEY, M.D.Abstracts 1 October 1937Volume 11, Issue 4Page: 651-656KeywordsCentral nervous systemExcretionGoutHospitalsPharmacologyUric acid ePublished: 1 December 2008 Issue Published: 1 October 1937 PDF downloadLoading ...