Peripheral Vascular Diseases
Authors: W. C. WATERS
Journal: Annals of Internal Medicine (1932)

Article1 April 1932Peripheral Vascular DiseasesTreatment with Acetyl-choline Hydrochloride*W. C. WATERS, M.D.W. C. WATERS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-5-10-1267 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptUnsatisfactory restoration of function so frequently follows surgical amputations for the gangrene of peripheral vascular diseases that interest in the treatment of such disturbances has been revived. Samuels1 views the gangrene in these conditions as a self-limiting process and recommends conservatism until so much tissue has been destroyed that nonfunction appears to be inevitable.Among palliative measures which have proved beneficial may be mentioned postural exercises,2 the use of Ringer's solution by duodenal tube and by hypodermoclysis,3 and the intravenous administration of sodium citrate4 and sodium iodide solution.5In 1926, Brown6introduced the use of typhoid vaccine given intravenously to...References1 SAMUELS SS: Treatment of gangrene due to thrombo-angiitis obliterans, Jr. Am. Med. Assoc., 1931, xcvi, 751-754. CrossrefGoogle Scholar2 BUERGER L: Circulatory diseases of the extremities, 1924, W. B. Saunders Co., Philadelphia. Google Scholar3 MEYER W: Etiology of thrombo-angiitis obliterans, (Berger), Jr. Am. Med. Assoc., 1918, lxxi, 1268-1272. CrossrefGoogle Scholar4 STEEL WA: Sodium citrate treatment of thrombo-angiitis obliterans, Jr. Am. Med. Assoc., 1921, lxxvi, 429-431. Google Scholar5 STERN WG: Blood viscosity in trophic disturbances of circulation, Jr. Bone and Joint Surg., 1924, xxii, 902-908. Google Scholar6 BROWN GE: Treatment of peripheral vascular disturbances of the extremities, Jr. Am. Med. Assoc., 1926, lxxxvii, 379-383. CrossrefGoogle Scholar7 ALLENSMITHWICK AWRH: Use of foreign protein in the treatment of peripheral vascular diseases, Jr. Am. Med. Assoc., 1928, cxi, 1161-1168. CrossrefGoogle Scholar8 SPURLING RG: Status of surgery of the sympathetic nervous system, South. Med. Jr., 1930, xxiii, 294-298. CrossrefGoogle Scholar9 VILLARETJUSTIN-BESANÇON ML: Syndrome de Raynaud; étude des pressions veinéuse et capillaire; action de l'histamine et de l'acétylcholine, Bull. et mém. Soc. méd. de hôp. d. Paris, 1926, l, 465-472. Google Scholar10 VILLARETJUSTIN-BESANÇON ML: The practical application of acetyl-choline, Med. Jr. and Rec., 1929, cxxviii, 343-345. Google Scholar11 VILLARETSCHIFF-WERTHEIMERJUSTIN-BESANCON ML: Effets de l'injection sous-cutanée d'acétyl-choline sur l'artère rétinienne de l'homme, Compt. rend. Soc. de biol., 1928, xcviii, 909-911. Google Scholar12 VILLARETJUSTIN-BESANÇON ML: The therapeutic use of acetyl-choline, Med. Jr. and Rec., 1930, cxxxii, 35-38. Google Scholar13 ADSONBROWN AWGE: Thoracic and lumbar sympathetic ganglionectomy in peripheral vascular diseases; therapeutic value, Jr. Am. Med. Assoc., 1930, xciv, 250-252. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Atlanta, Georgia*Received for publication, July 17, 1931. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByThe pharmacological and therapeutic effects of certain choline compounds 1 April 1932Volume 5, Issue 10Page: 1267-1273KeywordsPeripheral vascular diseaseSodiumTyphoidVaccines Issue Published: 1 April 1932 PDF DownloadLoading ...