Thyroid Disorders—A Half Century of Innovation
Authors: E. B. ASTWOOD
Journal: Annals of Internal Medicine (1965)

Article1 October 1965Thyroid Disorders—A Half Century of InnovationE. B. ASTWOOD, M.D., F.A.C.P.E. B. ASTWOOD, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-63-4-553 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTHE HORMONESThe discovery of Gudernatsch (1) that feeding of thyroid to tadpoles caused their metamorphosis into frogs was the headline news in the thyroid field when the American College of Physicians was founded in 1915. This was a striking demonstration of the potentiality of the hormone and of the complexity of its action; no longer could it be regarded as a substance that merely speeded the rate of metabolism. The phenomenon also provided a simple test for the active principle that was soon put to good use in physiological studies and in work on the purification of thyroid extracts....References1. 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Astwood, M.D., 171 Harrison Ave., Boston, Mass. 02111. Nextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByTREATMENT OF GRAVES' DISEASE: THE ADVANTAGES OF SURGERYSurgical Therapy of Graves’ DiseaseLymphocytic Thyroiditis and ThyrotoxicosisExophthalmic goiter —An etiological enigmaStudies of exophthalmic goiter 1 October 1965Volume 63, Issue 4Page: 553-558KeywordsHormonal therapyHormonesHospital medicineThyroidThyroid hormones Issue Published: 1 October 1965 CopyrightCopyright ©, 1965, by The American College of PhysiciansPDF DownloadLoading ...