Prinzmetal's Angina: Atropine Suppression
Authors: HIROFUMI YASUE
Journal: Annals of Internal Medicine (1974)

Letters1 April 1974Prinzmetal's Angina: Atropine SuppressionHIROFUMI YASUE, M.D., MASATO TOUYAMA, M.D., SATORU TANAKA, M.D., FUMIYA AKIYAMA, M.D.HIROFUMI YASUE, M.D., MASATO TOUYAMA, M.D., SATORU TANAKA, M.D., FUMIYA AKIYAMA, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-80-4-553_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Prinzmetal's variant form of angina is characterized by recurring attacks of chest pain that, in contrast to classical angina, occur at rest, are not precipitated by exercise or emotional stress, and are associated with transient S-T segment elevation in the electrocardiogram (1). The mechanism by which the attacks occur, however, remains unknown. We report a patient with Prinzmetal's variant form of angina, with normal coronary arteriograms, which was induced by parasympathomimetic drugs and suppressed by atropine.A 64-year-old man was admitted to hospital complaining of recurrent attacks of chest pain for 30 years; for the preceding 3...References1. PRINZMETALKENNAMERMERLISS MRR: Angina pectoris. 1. A variant form of angina pectoris. Am J Med 27:375-388, 1959 CrossrefMedlineGoogle Scholar2. EPSTEINREDWOODGOLDSTEIN SDR: Angina pectoris: pathophysiology, evaluation, and treatment. Ann Intern Med 75:263-296, 1971 LinkGoogle Scholar3. OLIVAPOTTSPLUSS PDR: Coronary arterial spasm in Prinzmetal's angina. Documentation by coronary arteriography. N Engl J Med 288:745-751, 1973 CrossrefMedlineGoogle Scholar4. FEIGL E: Parasympathetic control of coronary blood flow in dogs. Circ Res 25:509-519, 1969 CrossrefMedlineGoogle Scholar5. LEVY M: Sympathetic-parasympathetic interactions in the heart. Circ Res 29:437-445, 1971 CrossrefMedlineGoogle Scholar6. ZUBERBUHLERBOHR RD: Responses of coronary smooth muscle to catecholamines. Circ Res 16:431-440, 1965 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: HIROFUMI YASUE, M.D.; MASATO TOUYAMA, M.D.; SATORU TANAKA, M.D.; FUMIYA AKIYAMA, M.D.Affiliations: Division of Internal Medicine and Thoracic Surgery Shizuoka-City Hospital Shizuoka City, Japan 420 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byRole of acetylcholine spasm provocation test as a pathophysiological assessment in nonobstructive coronary artery diseaseInduction of coronary artery spasm by acetylcholine in patients with variant angina: possible role of the parasympathetic nervous system in the pathogenesis of coronary artery spasm.Abnormal heart rate response to exercise in vasospastic angina: Pathophysiologic mechanism in the provocation of coronary spasmPrinzmetal's Variant Angina Associated With Subarachnoid Hemorrhage: A Case ReportCessation of Smoking Followed by Prinzmetal's Variant Angina and Diffuse Esophageal SpasmVerbal conditioning of angina pectoris during exercise testingCoronary arterial spasm in Prinzmetal's angina: A proved hypothesis 1 April 1974Volume 80, Issue 4Page: 553-553KeywordsAnginaAtropineDrugsElectrocardiographyEmotionsExerciseIschemiaStable coronary artery disease ePublished: 1 December 2008 Issue Published: 1 April 1974 PDF downloadLoading ...