Cancer Chemotherapy and Raynaud's Phenomenon
Authors: J.J. GRAU
Journal: Annals of Internal Medicine (1983)

Letters and Corrections1 February 1983Cancer Chemotherapy and Raynaud's PhenomenonJ.J. GRAU, M.D., M. GRAU, M.D., A. MILLÁ, M.D., J. ESTAPÉ, M.D., M. MULET, M.D.J.J. GRAU, M.D.Search for more papers by this author, M. GRAU, M.D.Search for more papers by this author, A. MILLÁ, M.D.Search for more papers by this author, J. ESTAPÉ, M.D.Search for more papers by this author, M. MULET, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-98-2-258_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: In connection with the article by Vogelzang and associates (1) on Raynaud's phenomenon and its relation to vinblastine-bleomycin therapy, we wish to describe a new case.A 41-year-old man with an embryonal carcinoma in the mediastinum developed Raynaud's phenomenon with distal necrosis in the third month of treatment with vinblastine, bleomycin, and cisplatin (2). An arteriogram showed multiple arterial occlusions; the findings of a rheumatologic diagnostic study (including cryoglobulins) were negative. He smoked, but had never before had Raynaud manifestations. The severe pain was relieved only with intra-arterial vasodilators.This case calls attention to vinblastine-bleomycin as a...References1. VOGELZANGBOSLJOHNSONKENNEDY NGKB. Raynaud's phenomenon: a common toxicity after combination chemotherapy for testicular cancer. Ann Intern Med. 1981;95:288-92. LinkGoogle Scholar2. EINHORNDONOHUE LJ. Cis-diamminedichloroplatinum, vinblastine and bleomycin combination chemotherapy in disseminated testicular cancer. Ann Intern Med. 1977;87:293-8. LinkGoogle Scholar3. GOODMANGILMAN LA, eds. The Pharmacological Basis of Therapeutics. 6th Edition. New York: Macmillan publishing Co., Inc.; 1980. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Hospital Clínico y Provincial Barcelona 36 Spain PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByVasospastic Disease of the Upper Extremity: Primary Raynaud's SyndromeRaynaud's SyndromeVascular Toxicity of Antineoplastic AgentsTreatment of digital ischaemia associated with chemotherapy using the prostacyclin analogue IloprostAngina Pectoris and Therapy with Cisplatin, Vincristine, and BleomycinAndrew C. Dixon, MD, Jeffrey M. Nakamura, MD, Noboru Oishi, MD, Dennis H. Wachi, MD, Osamu Fukuyama, MDAcute Vascular Ischemic Events After Cisplatin-Based Combination Chemotherapy for Germ-Cell Tumors of the TestisDONALD C. DOLL, M.D., ALAN F. LIST, M.D., F. ANTHONY GRECO, M.D., JOHN D. HAINSWORTH, M.D., KENNETH R. HANDE, M.D., DAVID H. JOHNSON, M.D.Bleomycin and Raynaud's PhenomenonD. ADOUE, P. ARLETAcral Erythema and HydroxyureaFRANCES SANDLER SILVER, M.D., LUIS R. ESPINOZA, M.D., ROBERT C. HARTMANN, M.D. 1 February 1983Volume 98, Issue 2Page: 258-258KeywordsCancer chemotherapyNecrosisRaynaud syndromeVasodilators Issue Published: 1 February 1983 PDF DownloadLoading ...