tbuckley/cabot-search huggingface dataset:
The Effect of Weight Loss in Overweight, Lactating Women on the Growth of Their Infants
Authors: Cheryl A. Lovelady, Kimberly E. Garner, Kerri L. Moreno, John P. Williams
Journal: New England Journal of Medicine (2000)

The retention of weight gained during pregnancy may contribute to obesity. Lactation should promote weight loss, but weight loss is highly variable among lactating women. The risks associated with the restriction of energy intake during lactation have not been adequately evaluated. The purpose of this study was to determine whether weight loss by women during lactation affects the growth of their infants.
Distinct roles for LFA-1 affinity regulation during T-cell adhesion, diapedesis, and interstitial migration in lymph nodes
Authors: Eun Jeong Park, António Peixoto, Yoichi Imai, Ahmad Goodarzi, Guiying Cheng, Christopher V. Carman, Ulrich H. von Andrian, Motomu Shimaoka
Journal: Blood (2009)
Basilar Artery Migraine
Authors: HIKARU SETO, MASASHI SHIMIZU, RYUSUKE FUTATSUYA, MASANARI KAGEYAMA, YIWEI WU, TETSUYA KAMEI, RYOKO SHIBATA, MASAO KAKISHITA
Journal: Clinical Nuclear Medicine (1994)

The authors present a case of basilar artery migraine in a 33-year-old woman who was initially misdiagnosed as having a cerebrovascular or mental disorder and subjected to MRI and cerebral angiography, which, however, did not show any pathologic findings. During admission to the university hospital, she lost consciousness. An emergency Tc-99m HMPAO brain SPECT showed a significant decrease of regional cerebral blood flow in the right temporal and occipital cortices, and right cerebellar hemisphere, where regional cerebral blood flow was decreased by 10-24% as compared to the left side. The second brain SPECT during a symptom-free phase showed the reversion of regional cerebral blood flow to normal in these areas. Basilar artery migraine was diagnosed by the finding of reversible ischemia in the territory of the right basilar artery on brain SPECT images and the clinical picture.
Scintigraphic Demonstration of Coexisting Adenoma and Metastasis of the Adrenal Gland in a Patient with Bronchogenic Carcinoma
Authors: HIROAKI HOSHI, SEISHI JINNOUCHI, SEIJI ONO, YASUSHI KIHARA, KEIKO ARAKAWA, MIDORI TAKEUCHI, KATSUSHI WATANABE
Journal: Clinical Nuclear Medicine (1984)

Metastasis of the adrenal gland is frequently founded In patients with advanced bronchogenic carcinoma. The scintigraphic findings of a patient with adenoma and metastasis in the same adrenal gland is presented.
How Google is changing medicine
Authors: Dean Giustini
Journal: BMJ (2005)

published on smallpox and measles: his texts continued to be reprinted well into the 19th century.The medical texts of Ibn Rushd (Averroes) were also widely used in European universities.Ibn Sina (Avicenna) was known in the West as "the prince of physicians."His synthesis of Islamic medicine, al-Qanun fi'l tibb (The Canon of Medicine), was the final authority on medical matters in Europe for several centuries.Although Ibn Sina made advances in pharmacology and in clinical practice, his greatest contribution was probably in the philosophy of medicine.He created a system of medicine that today we would call holistic and in which physical and psychological factors, drugs, and diet were combined in treating patients. 7 Eventually, the Islamic civilisation constructed by the Arabs went into decline.In the east, new powers rose: first the Mongols, who in 1258 devastated Baghdad, the greatest Arab city of its day, and later the Ottoman Turks, who brought large parts of the Arab world into their new empire from the 14th century onwards.Weakened by internal strife and civil conflict, most of the Islamic cities of Spain had been conquered by Christian armies by the 14th century.The last Islamic state in Spain, Granada, surrendered to the Spanish in 1492 and its ruler, Boabdil, was exiled to North Africa. 8 The flow of technology and ideas from the Islamic world to the West slowed and, in the past 600 years, has reversed.Academics and politicians still debate the reasons for and consequences of this decline in Islamic science and technology.The legacy of Islamic civilisation, though, remains with us in making possible Europe's own scientific and cultural renaissance.
Effect of plasma exchange in rhesus immunisation.
Authors: D Tovey, E A Robinson
Journal: BMJ (1980)

to medical schools should include measures to detect vulnerability, and the curriculum should embody programmes which will help the student to cope with later professional stresses.Faculty advisors, tutors, and organised peer groups should be aware of their duty to recognise and intervene at an early stage rather than to wait for the GMC to take action when problems may be ineradicably established.
Interferon-α or homoharringtonine as salvage treatment for chronic myeloid leukemia patients who acquire the T315I BCR-ABL mutation
Authors: Hugues de Lavallade, Jamshid S. Khorashad, Howard P. Davis, Dragana Milojkovic, Jaspal S. Kaeda, John M. Goldman, Jane F. Apperley, David Marin
Journal: Blood (2007)
Dextroamphetamine for Epilepsy
Authors: Samuel Livingston
Journal: JAMA (1975)

OUR EXPERIENCE supports the findings of the Boston Collaborative Drug Surveillance Program, prepared by Jick,<sup>1</sup>which did not confirm the relationship of amphetamine therapy to the development of Hodgkin disease described by Newell et al.<sup>2</sup> Over the past 30 years, we have prescribed the amphetamines, primarily dextroamphetamine sulfate (Dexedrine), to at least 10,000 epileptic patients and are impressed with their singular freedom from untoward reactions. Some of these patients have taken with impunity an amphetamine daily for periods ranging from 20 to 30 years. It is noteworthy that we have not observed the occurrence of lymphadenopathy, pseudolymphoma, lymphocytic or lymphoblastic lymphosarcoma, or Hodgkin disease in any of our patients receiving amphetamines during this period of time. We have also treated approximately 1,300 children with the hyperkinetic behavioral syndrome, including 400 without a concomitant seizure disorder, with daily amphetamine therapy. Prolonged follow-up study of this group did not disclose
Do clinical findings associate with radiographic osteoarthritis of the knee?
Authors: A A Claessens, J S Schouten, F A van den Ouweland, H A Valkenburg
Journal: Annals of the Rheumatic Diseases (1990)

From a population survey of 2865 subjects, test characteristics of a number of clinical findings relating to knee osteoarthritis were calculated against the standard of radiographic diagnosis. The clinical findings included from the history were age, gender, current pain in the knee, swollen knee, pain in both hands, morning stiffness, osteoarthritis in any joint, pain or stiffness, or both, in knees or hips when rising from seated position, and pain in knees or hips while climbing stairs; and from the physical examination: Quetelet's index, Heberden's nodes, bony enlargement, palpable effusion, soft tissue swelling, limitation of knee function, pain with knee flexion, bony tenderness and, finally, the latex fixation test. Of 18 clinical variables, all but Heberden's nodes, palpable knee effusion, pain in both hands, and latex fixation test showed a significant association after adjustment for age. Neither one single variable nor a combination could predict radiographic osteoarthritis of the knee with reasonable accuracy and thus be applicable in clinical practice. The x ray film, therefore, keeps its place in the diagnosis of knee osteoarthritis in general practice as well as in epidemiological research.
Researchers fear effects of EU draft directive on animal research
Authors: G. Watts
Journal: BMJ (2009)

Nine UK bioscience organisations working in the academic, commercial, and charitable sectors have issued a joint “declaration of concern” about the impact of a European Union draft directive on animal research. If implemented in full the directive would stop some animal research and increase costs and bureaucracy without achieving the intended goal of improving animal welfare, they say.

The new directive (86/609) proposes extensive changes to existing European legislation on animal experimentation. It would severely restrict or in some cases phase out research that involves non-human primates, and bring new species within the scope of legislation, including types of invertebrate and their larvae. It also aims to set new …
Effect of the California Tobacco Control Program on Personal Health Care Expenditures
Authors: James M Lightwood, Alexis Dinno, Stanton A Glantz
Journal: PLoS Medicine (2008)

Background Large state tobacco control programs have been shown to reduce smoking and would be expected to affect health care costs. We investigate the effect of California's large-scale tobacco control program on aggregate personal health care expenditures in the state. Methods and Findings Cointegrating regressions were used to predict (1) the difference in per capita cigarette consumption between California and 38 control states as a function of the difference in cumulative expenditures of the California and control state tobacco control programs, and (2) the relationship between the difference in cigarette consumption and the difference in per capita personal health expenditures between the control states and California between 1980 and 2004. Between 1989 (when it started) and 2004, the California program was associated with $86 billion (2004 US dollars) (95% confidence interval [CI] $28 billion to $151 billion) lower health care expenditures than would have been expected without the program. This reduction grew over time, reaching 7.3% (95% CI 2.7%–12.1%) of total health care expenditures in 2004. Conclusions A strong tobacco control program is not only associated with reduced smoking, but also with reductions in health care expenditures.
All general practices must register with regulator by 2012
Authors: J. Wise
Journal: BMJ (2009)

From 2012 all 8500 general practices in England will have to be registered with the Care Quality Commission, in line with all other providers of health and social care services.

The process of regulating the safety and quality of all health and social care services against a single set of registration requirements is already under way. From April it has been a legal requirement for NHS trusts that provide healthcare services directly to patients to register with the commission and show that they comply with requirements on hospital associated infections.

Of the 388 trusts in this category, the commission has found 21 that did not fully comply with the government’s …
Michigan Students Protest.
Authors: Victor C. Vaughan
Journal: JAMA (1903)

Ann Arbor, March 21, 1903. <h3>To the Editor:</h3> —On behalf of the faculty and students of the Department of Medicine and Surgery of the University of Michigan I wish to enter a most vigorous protest against your editorial on page 787. [The Journal, March 21.] You endeavor to apparently keep within the bounds of truth and at the same time you give a wholly false impression. You start by saying that the students of "certain medical colleges of that state" (Michigan) have protested against the passage of the proposed medical act, and after very properly condemning the position of such students, you wind up with the following: "We hope the students of the Michigan medical colleges will see the unwisdom of their action and assist, rather than oppose, those who are fighting for the elevation of the standard of the profession which they are about to enter." This statement implies
Termination and Inhibition of Recurrent Tachycardias by Implanted Pervenous Pacemakers
Authors: ARTHUR J. MOSS, ROBERT J. RIVERS
Journal: Circulation (1974)

Three patients are described with recurrent paroxysmal tachycardia who required implanted pervenous demand pacemakers for the control of repetitive tachyarrhythmias. One patient had frequent weekly episodes of life-inhibiting supraventricular tachycardia (SVT) lasting hours to days and refractory to antiarrhythmic drugs. A coronary sinus atrial demand pacemaker at 72 beats per minute was implanted. During the subsequent two months, the patient quickly terminated nine episodes of SVT by activating the generator with an external magnet and competitively pacing the atrium. The second patient had frequent daily episodes of SVT and secondary angina despite vigorous antiarrhythmic medication. Demand ventricular pacing at a rate of 88 beats per minute prevented the recurrence of SVT during the seven month follow-up. A third patient with an old myocardial infarction had frequent biweekly episodes of ventricular tachycardia (VT) refractory to conventional treatment. A ventricular demand pacemaker was implanted, and three episodes of VT were terminated by magnetically activated competitive ventricular pacing at 64 beats per minute. Augmentation of the demand pacemaker rate to 86 beats per minute inhibited the recurrence of VT during a five month follow-up. The rates of the tachycardias were less than 160 beats per minute in all three cases, and evidence suggests a re-entrant or reciprocating mechanism for the tachyarrhythmias. The electrophysiologic rationale for pacemaker therapy in certain types of recurrent SVT and VT is discussed.
MENINGITIS IN MAN CAUSED BY A FILTERABLE VIRUS
Authors: T. F. McNair Scott, Thomas M. Rivers
Journal: The Journal of Experimental Medicine (1936)

The clinical pictures presented by two men suffering from an acute bacteria-free lymphocytic meningitis, and the method of obtaining a virus from their spinal fluids were described. Evidence was then adduced to show that the virus was really in the spinal fluids, that the strains of virus obtained from the two patients were identical or closely related, and that the active agent in the spinal fluids was etiologically significant.
1991 Appropriations For Cancer Research Approved by Senate
Authors: Sylvia Bennett
Journal: JNCI Journal of the National Cancer Institute (1990)

Journal Article 1991 Appropriations For Cancer Research Approved by Senate Get access Sylvia Bennett Sylvia Bennett Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 82, Issue 22, 21 November 1990, Pages 1738–1739, https://doi.org/10.1093/jnci/82.22.1738 Published: 21 November 1990
Medical injuries in US hospitals cause more than 30 000 deaths each year
Authors: S. Mayor
Journal: BMJ (2003)

Glucocorticoids precociously induce fetal rat UGT1A6 and potentiate polycyclic aromatic hydrocarbon (PAH)-dependent induction of this enzyme in vivo and in isolated rat hepatocytes. To establish whether induction was due to glucocorticoid receptor (GR), luciferase reporter vectors were tested in transfection assays with HepG2 cells. Using a reporter construct containing approximately 2.26 kilobases of the 5′-flanking region of the UGT1A6-noncoding leader exon (A1*), dexamethasone increased basal activity 3- to 7-fold in cells cotransfected with an expression plasmid for GR. PAH increased gene expression 23-fold, but the presence of dexamethasone only induced PAH-dependent expression by 1.5-fold, suggesting interaction between GR and the aryl hydrocarbon (Ah) receptor. Furthermore, the GR antagonist RU 38486 [17β-hydroxy-11β-(4-dimethylamino-phenyl)-17α-(prop-1-ynyl)-estra-4,9-dien-3-one] was a partial agonist that increased, rather than inhibited, basal activity 3-fold. 5′-deletion analysis defined the 5′-boundary for a functional glucocorticoid-responsive unit between base pairs –141 and –118 relative to the transcription start site. This region contains the Ah receptor response element (AhRE), and both PAH and glucocorticoid-dependent gene activation were lost when this area was deleted. Mutation of a single base pair located in the AhRE region simultaneously reduced induction by PAH and increased glucocorticoid induction. Thus, the sequences of both the AhRE and glucocorticoid response elements seem to overlap, suggesting that Ah receptor binding may decrease glucocorticoid-dependent induction due to interactions of these two <i>cis-</i>acting elements. Mutation of a putative GRE located between base pair –81 and –95 reduced, but did not completely eliminate, glucocorticoid-dependent induction of the reporter, suggesting that a nonclassic mechanism of induction is involved in this response.
Serum α-L-Fucosidase: A New Marker for the Diagnosis of Primary Hepatic Carcinoma?
Authors: Yves Deugnier, Véronique David, Pierre Brissot, Philippe Mabo, Damien Delamaire, Michel Messner, Michel Bourel, Jean-Yves Legall
Journal: Hepatology (1984)

alpha-L-fucosidase, a lysosomal enzyme which catabolizes fucoproteins, was studied in sera from 30 controls, 32 patients with primary hepatic carcinomas, 24 patients with secondary metastatic liver carcinomas and 36 patients with cirrhosis. Serum alpha-L-fucosidase was increased in primary hepatic carcinomas (145.5 +/- 12 nkat per liter) with a high statistical significance versus controls (51.4 +/- 4.5 - p less than 10(-7], secondary metastatic liver carcinomas (58.9 +/- 6.4 - p less than 10(-5] and cirrhotics (71.3 +/- 6 - p less than 10(-5). A level exceeding 110 was a useful marker for the diagnosis of primary hepatic carcinoma with 75% sensitivity and 90% specificity.
Thrombosis and Anticoagulant Therapy: Proceedings of a Symposium held at Queens College, Dundee, Sept. 29-30 and Oct. 2, 1960
Authors: Irving S. Wright
Journal: JAMA (1961)

These proceedings represent a condensed review of the present thinking of a group of distinguished investigators and clinicians who gathered together under the sponsorship of the University of St. Andrews to discuss thrombosis and anticoagulant therapy. The views expressed represent a good cross section of those held by informed students of cardiovascular and hematological problems of Great Britain and continental Europe. In most respects, these coincide with the accepted concepts in the United States, but there are enough differences in details to warrant careful study of this volume by all who are interested in this area. The subjects covered were many, but they could be grouped in the following general categories: current concepts of blood coagulation in relation to vascular disease; the organization and laboratory control of anticoagulant therapy; the use of anticoagulants in myocardial infarction in peripheral and cerebral vascular disease and in prophylaxis; the heparinoids and their place
Quality Measurements in Pediatrics
Authors: Scott A. Lorch
Journal: JAMA Pediatrics (2012)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Pediatrics HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Pediatrics journal
Steatocystoma multiplex, oligodontia and partial persistent primary dentition associated with a novel keratin 17 mutation
Authors: J.K. Gass, N.J. Wilson, F.J.D. Smith, E.B. Lane, W.H.I. McLean, E. Rytina, I. Salvary, N.P. Burrows
Journal: British Journal of Dermatology (2009)

Journal Article Steatocystoma multiplex, oligodontia and partial persistent primary dentition associated with a novel keratin 17 mutation Get access J.K. Gass, J.K. Gass Department of Dermatology, Box 46, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2QQ, U.K. Search for other works by this author on: Oxford Academic Google Scholar N.J. Wilson, N.J. Wilson Cancer Research UK Cell Structure Research Group Search for other works by this author on: Oxford Academic Google Scholar F.J.D. Smith, F.J.D. Smith Epithelial Genetics Group, Division of Molecular Medicine, University of Dundee, Dundee, U.K. Search for other works by this author on: Oxford Academic Google Scholar E.B. Lane, E.B. Lane Cancer Research UK Cell Structure Research GroupA*STAR Institute for Medical Biology, Biopolis, Singapore Search for other works by this author on: Oxford Academic Google Scholar W.H.I. McLean, W.H.I. McLean Epithelial Genetics Group, Division of Molecular Medicine, University of Dundee, Dundee, U.K. Search for other works by this author on: Oxford Academic Google Scholar E. Rytina, E. Rytina Department of Histopathology, Addenbrooke's Hospital, Cambridge, U.K. Search for other works by this author on: Oxford Academic Google Scholar I. Salvary, I. Salvary Department of Dermatology, James Paget University Hospitals NHS Trust, Great Yarmouth, U.K. E‐mail: julia.gass@addenbrookes.nhs.uk Search for other works by this author on: Oxford Academic Google Scholar N.P. Burrows N.P. Burrows Department of Dermatology, Box 46, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2QQ, U.K. Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 161, Issue 6, 1 December 2009, Pages 1396–1398, https://doi.org/10.1111/j.1365-2133.2009.09383.x Published: 01 December 2009
GELATIN ADDED TO DIETS OF ARTIFICIALLY FED INFANTS
Authors: JULIUS H. HESS
Journal: JAMA (1927)

These feeding studies were carried out on a group of thirty-four average, normal, artificially fed infants at the University of Illinois Educational and Research Hospital Dispensary, and at three city infant welfare stations, conducted by the health department of Chicago. There were about thirteen hundred breast and bottle fed infants in attendance at the three welfare stations and the university dispensary from which we selected the individual cases for our feeding studies. Breast feeding, in whole or in part, is the slogan of the welfare stations. As our work required artificially fed infants whose mothers would promise to cooperate with us in every detail, we thought ourselves fortunate in finding seventy-four infants who we believed would answer our requirements. As we expected to conduct the experimental study over a period of at least four months, only young infants could be used. Seventy-five per cent of our infants were under 3
Cytomegalovirus reactivation after allogeneic transplantation promotes a lasting increase in educated NKG2C+ natural killer cells with potent function
Authors: Bree Foley, Sarah Cooley, Michael R. Verneris, Michelle Pitt, Julie Curtsinger, Xianghua Luo, Sandra Lopez-Vergès, Lewis L. Lanier, Daniel Weisdorf, Jeffrey S. Miller
Journal: Blood (2011)