Treatment of Community-Acquired Methicillin-Resistant <i>Staphylococcus aureus</i> Infection
Authors: Kleper N.F. de Almeida, Larry M. Bush
Journal: Annals of Internal Medicine (2006)

Letters1 August 2006Treatment of Community-Acquired Methicillin-Resistant Staphylococcus aureus InfectionKleper N.F. de Almeida, MD and Larry M. Bush, MDKleper N.F. de Almeida, MDFrom JFK Medical Center, Atlantis, FL 33462.Search for more papers by this author and Larry M. Bush, MDFrom JFK Medical Center, Atlantis, FL 33462.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-145-3-200608010-00016 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR: We were delighted to read the article by King and associates (1) on the emergence of community-acquired methicillin-resistant Staphylococcus aureus (MRSA) USA 300 clone as the predominant cause of community-onset S. aureus skin and soft-tissue infections in the Atlanta, Georgia, area. However, we disagree with the authors' statement that “the efficacy of nonglycopeptide antimicrobial agents in treating MRSA skin and soft-tissue infections remains incompletely defined, and clinical trials are needed to better define their role.” Despite wide clinical experience with and acceptance of glycopeptides (for example, vancomycin) as the treatment of choice, limited controlled data exist to ...References1. King MD, Humphrey BJ, Wang YF, Kourbatova EV, Ray SM, Blumberg HM. Emergence of community-acquired methicillin-resistant Staphylococcus aureus USA 300 clone as the predominant cause of skin and soft-tissue infections. Ann Intern Med. 2006;144:309-17. [PMID: 16520471] LinkGoogle Scholar2. Weigelt J, Itani K, Stevens D, Lau W, Dryden M, Knirsch C, et al. Linezolid versus vancomycin in treatment of complicated skin and soft tissue infections. Antimicrob Agents Chemother. 2005;49:2260-6. [PMID: 15917519] CrossrefMedlineGoogle Scholar3. Kollef MH, Micek ST. Methicillin-resistant Staphylococcus aureus: a new community-acquired pathogen? Curr Opin Infect Dis. 2006;19:161-8. [PMID: 16514341] CrossrefMedlineGoogle Scholar4. Markowitz N, Quinn EL, Saravolatz LD. Trimethoprim-sulfamethoxazole compared with vancomycin for the treatment of Staphylococcus aureus infection. Ann Intern Med. 1992;117:390-8. [PMID: 1503330] LinkGoogle Scholar5. Martinez-Aguilar G, Hammerman WA, Mason EO, Kaplan SL. Clindamycin treatment of invasive infections caused by community-acquired, methicillin-resistant and methicillin-susceptible Staphylococcus aureus in children. Pediatr Infect Dis J. 2003;22:593-8. [PMID: 12867833] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Kleper N.F. de Almeida, MD; Larry M. Bush, MDAffiliations: From JFK Medical Center, Atlantis, FL 33462.Disclosures: Dr. de Almeida is a member of the Pfizer Speakers' Bureau. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoEmergence of Community-Acquired Methicillin-Resistant Staphylococcus aureus USA 300 Clone as the Predominant Cause of Skin and Soft-Tissue Infections Mark D. King , Bianca J. Humphrey , Yun F. Wang , Ekaterina V. Kourbatova , Susan M. Ray , and Henry M. Blumberg Treatment of Community-Acquired Methicillin-Resistant Staphylococcus aureus Infection James R. Johnson Treatment of Community-Acquired Methicillin-Resistant Staphylococcus aureus Infection Henry M. Blumberg , Susan M. Ray , and Mark D. King Metrics Cited byChanges in prescriptive practices in skin and soft tissue infections associated with the increased occurrence of community acquired methicillin resistant Staphylococcus aureus 1 August 2006Volume 145, Issue 3Page: 231-232KeywordsAntimicrobialsInflammationMethicillin-resistant staphylococcus aureusNecrosisPathogensRoutes of administrationSkin infectionsStaphylococcal infectionToxinsVancomycin ePublished: 1 August 2006 Issue Published: 1 August 2006 Copyright & PermissionsCopyright © 2006 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...