Effects of Antiplatelet Therapy on Mortality and Cardiovascular and Bleeding Outcomes in Persons With Chronic Kidney Disease
Authors: William Kussmaul
Journal: Annals of Internal Medicine (2012)

Letters21 August 2012Effects of Antiplatelet Therapy on Mortality and Cardiovascular and Bleeding Outcomes in Persons With Chronic Kidney DiseaseWilliam Kussmaul, MDWilliam Kussmaul, MDFrom Hahnemann University Hospital, Philadelphia, PA 19102.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-157-4-201208210-00023 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Palmer and colleagues (1) have usefully collected information on the use of antiplatelet agents in patients who have both coronary artery disease and chronic kidney disease (CKD). They conclude that the benefits of both primary and secondary prevention are uncertain and that patients who have CKD may have a greater risk for bleeding. The review also implies that these agents should not be used in patients with CKD until better data are available.Unfortunately, Palmer and colleagues may have done a disservice to the many patients with CKD who have coronary stents and to their physicians. Almost ...Reference1. Palmer SC, Di Micco L, Razavian M, Craig JC, Perkovic V, Pellegrini F, et al. Effects of antiplatelet therapy on mortality and cardiovascular and bleeding outcomes in persons with chronic kidney disease: a systematic review and meta-analysis. Ann Intern Med. 2012;156:445-59. [PMID: 22431677] LinkGoogle Scholar Author, Article, and Disclosure InformationAuthors: William Kussmaul, MDAffiliations: From Hahnemann University Hospital, Philadelphia, PA 19102.Disclosures: None disclosed. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoEffects of Antiplatelet Therapy on Mortality and Cardiovascular and Bleeding Outcomes in Persons With Chronic Kidney Disease Suetonia C. Palmer , Lucia Di Micco , Mona Razavian , Jonathan C. Craig , Vlado Perkovic , Fabio Pellegrini , Massimiliano Copetti , Giusi Graziano , Gianni Tognoni , Meg Jardine , Angela Webster , Antonio Nicolucci , Sophia Zoungas , and Giovanni F.M. Strippoli Effects of Antiplatelet Therapy on Mortality and Cardiovascular and Bleeding Outcomes in Persons With Chronic Kidney Disease R. Brooks Robey and Daniel J. O'Rourke Effects of Antiplatelet Therapy on Mortality and Cardiovascular and Bleeding Outcomes in Persons With Chronic Kidney Disease Giovanni F.M. Strippoli , Suetonia C. Palmer , and Jonathan C. Craig Metrics Cited byImpact of Antiplatelet Therapy and Platelet Reactivity Testing on Cardiovascular Outcomes in Patients with Chronic Kidney DiseaseImpact of restarting warfarin therapy in renal disease anticoagulated patients with gastrointestinal hemorrhage 21 August 2012Volume 157, Issue 4Page: 302KeywordsAntiplatelet therapyChronic kidney diseaseDrug therapyEvidence based medicineHemorrhageMortalityStable coronary artery diseaseStent implantationSystematic reviewsThrombosis ePublished: 21 August 2012 Issue Published: 21 August 2012 Copyright & PermissionsCopyright © 2012 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...