Hormonal Therapy of Breast Cancer
Authors: HENRY M. LEMON
Journal: Annals of Internal Medicine (1978)

Letters and Corrections1 September 1978Hormonal Therapy of Breast CancerHENRY M. LEMON, M.D.HENRY M. LEMON, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-89-3-422_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Drs. Legha, Davis, and Muggia in an otherwise excellent assessment of some of the current advances in hormonal therapy of breast cancer (Ann Intern Med88:69-77, 1978) unfortunately have perpetuated misconceptions about "medical" adrenalectomy that we should like to call to the attention of your readers. It may be true, as they state on p. 73, that corticosteroid therapy produces a somewhat lower objective remission rate of breast cancer metastases than ablative surgery, but the latter procedures are seldom used with major visceral metastases in brain, liver, or lung, which have a lower objective response rate. Two...References1. LEMON H: Prednisone therapy of advanced mammary cancer. Cancer 12:93-107, 1959 CrossrefMedlineGoogle Scholar2. SIITERI P, HARTWELL D, EDWARDS C, and MCDONALD P: Estrogen and endometrial carcinoma, in Proceedings of the Fourth International Congress of Endocrinology, Washington, D.C., 18-24 June 1972. Amsterdam, Excerpta Medica, pp. 1237-1242 Google Scholar3. PROCOPE B and ADLERKREUTZ H: Oestrogen production in the postmenopausal woman. Front Horm Res 2:55-73, 1973 CrossrefGoogle Scholar4. NISSEN-MEYER R: The role of prophylactic castration in the therapy of human mammary cancer. Eur J Cancer 3:395-403, 1967 CrossrefMedlineGoogle Scholar5. LIPPMAN M, BOLAN G, and HUFF K: The effects of estrogen and antiestrogens on hormone-responsive human breast cancer in long-term tissue culture. Cancer Res 36:4595-4601, 1976 MedlineGoogle Scholar6. WITT J, GARDNER B, GORDON G, GRAHAM W, and THOMAS A: Secondary hormonal therapy of disseminated breast cancer. Arch Intern Med 111:557-563, 1963 CrossrefMedlineGoogle Scholar1. SEGALOFF A, CARABASI R, HORWITT B, SCHLOSSER J, and MURISON P: Hormonal therapy of cancer of the breast. VI. Effect of ACTH and cortisone on clinical course and hormonal excretion. Cancer 7:331-334, 1954 CrossrefMedlineGoogle Scholar2. DAO T, TAN E, and BROOKS V: A comparative evaluation of adrenalectomy and cortisone in the treatment of advanced mammary carcinoma. Cancer 14:1259-1265, 1961 CrossrefMedlineGoogle Scholar3. VAN GILSE H: Long-term treatment with corticosteroids of patients with metastatic breast cancer. Cancer Chemother Rep 16:293-298, 1962 MedlineGoogle Scholar4. GALE K, SHEEHE P, GOULD L, and ROHNER R: Treatment of advanced breast cancer with aminoglutethimide. An 8-year experience (abstract). Clin Res 24:376, 1976 Google Scholar5. HARVEY A, SANTEN R, OSTERMAN J, WHITE D, and LIPTON A: A comparative clinical trial of medical adrenalectomy vs. transphenoidal hypophysectomy in advanced breast cancer (abstract). Proc Am Assoc Cancer Res 17:219, 1976 Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: HENRY M. LEMON, M.D.Affiliations: University of Nebraska Medical Center Omaha, NB 68105 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 September 1978Volume 89, Issue 3Page: 422-423KeywordsAdrenalectomyBrainBreast cancerCorticosteroid therapyHormonal therapyLiverLung and intrathoracic tumorsSurgery ePublished: 1 December 2008 Issue Published: 1 September 1978 PDF downloadLoading ...