Tissue Is the Issue: Is Endoscopic Ultrasonography with or without Fine-Needle Aspiration Biopsy in the Staging of Non-Small-Cell Lung Cancer an Advance?
Authors: Peter White
Journal: Annals of Internal Medicine (1997)

Editorials15 October 1997Tissue Is the Issue: Is Endoscopic Ultrasonography with or without Fine-Needle Aspiration Biopsy in the Staging of Non-Small-Cell Lung Cancer an Advance?Peter White Jr., MD and David S. Ettinger, MDPeter White Jr., MDThe Johns Hopkins University School of Medicine Baltimore, MD 21287Dr. Ettinger: Johns Hopkins Oncology Center, 600 North Wolfe Street, Baltimore, MD 21287.Search for more papers by this author and David S. Ettinger, MDThe Johns Hopkins University School of Medicine Baltimore, MD 21287Dr. Ettinger: Johns Hopkins Oncology Center, 600 North Wolfe Street, Baltimore, MD 21287.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-127-8_Part_1-199710150-00011 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Non-small-cell lung cancer is the leading cause of death from malignancy in the United States [1]. The TNM (T = primary tumor, N = regional lymph nodes, M = distant metastasis) staging system for this type of cancer subdivides patients into anatomic groups. This system is central to determining treatment options and prognosis and to comparing survival among therapeutic trials [1]. In the absence of distant metastasis, mediastinal lymph node metastasis in non-small-cell lung cancer is a critical issue. Almost half of patients with this type of cancer present with metastasis to the mediastinal lymph nodes, a characteristic that is ...References1. Pretreatment evaluation of non-small-cell lung cancer. The American Thoracic Society and the European Respiratory Society. Am J Respir Crit Care Med. 1997; 156:320-32. Google Scholar2. Mountain CF. Lung cancer staging classification. Clin Chest Med. 1993; 14:43-51. Google Scholar3. McKenna RJ Jr, Libshitz HI, Mountain CE, McMurtney MJ. Roentgenographic evaluation of mediastinal nodes for preoperative assessment in lung cancer. Chest. 1985; 88:206-10. Google Scholar4. McLoud TC, Bourgouin PM, Greenberg RW, Kosiuk JP, Templeton PA, Shepard JA, et al. Bronchogenic carcinoma: analysis of staging in the mediastinum with CT by correlative lymph node mapping and sampling. Radiology. 1992; 182:319-23. Google Scholar5. Laurent F, Drouillard J, Dorcier F, Velly JF, Barat JL, Grelet P, et al. Bronchogenic carcinoma staging: CT vs. MR imaging. Assessment with surgery. Eur J Cardiothorac Surg. 1988; 2:31-6. Google Scholar6. Webb WR, Gatsonis C, Zerhouni EA, Heelan RT, Glazer GM, Francis IR, et al. CT and MR imaging in staging non-small cell bronchogenic carcinoma: report of the Radiologic Diagnostic Oncology Group. Radiology. 1991; 178:705-13. Google Scholar7. Gress FG, Savides TJ, Sandler A, Kesler K, Conces D, Cummings O, et al. Endoscopic ultrasonography, fine-needle aspiration biopsy guided by endoscopic ultrasonography, and computed tomography in the preoperative staging of non-small-cell lung cancer: a comparison study. Ann Intern Med. 1997; 127:604-12. Google Scholar8. Giovannini M, Seitz JF, Monges G, Perrier H, Rabbia I. Fine-needle aspiration cytology guided by endoscopic ultrasonography: results in 141 patients. Endoscopy. 1995; 27:171-7. Google Scholar9. Silvestri GA, Hoffman BJ, Bhutani MS, Hawes RH, Coppage L, Sanders-Cliette A, et al. Endoscopic ultrasound with fine-needle aspiration in the diagnosis and staging of lung cancer. Ann Thorac Surg. 1996; 61:1441-6. Google Scholar10. Vilman P, Hancke S, Hendrickson FW, Jacobsen GK. Endosonographically-guided fine needle aspiration biopsy of malignant lesions in the upper gastrointestinal tract. Endoscopy. 1993; 25:523-7. Google Scholar11. Chin R Jr, Ward R, Keyes JW, Choplin RH, Reed JC, Wallenhaupt S, et al. Mediastinal staging of non-small-cell lung cancer with positron emission tomography. Am J Respir Crit Care Med. 1995; 152:2090-6. Google Scholar12. Sazon DA, Santiago SM, Soo Hoo GW, Khonsary A, Brown C, Mandelkern M, et al. Fluorodeoxyglucose-positron emission tomography in the detection and staging of lung cancer. Am J Respir Crit Care Med. 1996; 153:417-21. Google Scholar13. Anzai Y, Blackwell KE, Hirschowitz SL, Rogers JW, Sato Y, Yuh WT, et al. Initial clinical experience with dextran-coated superparamagnetic iron oxide for detection of lymph node metastases in patients with head and neck cancer. Radiology. 1994; 192:709-15. Google Scholar14. Ginsberg RJ, Rice TW, Goldberg M, Waters PF, Schmocker BJ. Extended cervical mediastonoscopy. A single staging procedure for bronchogenic carcinoma of the left upper lobe. J Thorac Cardiovasc Surg. 1987; 94:673-8. Google Scholar15. Funatsu T, Matsubara Y, Hatakenaka R, Kosaba S, Yasuda Y, Ikeda S. The role of mediastinoscopic biopsy in preoperative assessment of lung cancer. J Thorac Cardiovasc Surg. 1992; 104:1688-95. Google Scholar16. Shannon JJ, Bude RO, Orens JB, Becker FS, Whyte RI, Rubin JM, et al. Endobronchial ultrasound-guided needle aspiration of mediastinal adenopathy. Am J Respir Crit Care Med. 1996; 153:1424-30. Google Scholar17. Wang KP, Brower R, Haponik EF, Siegelman S. Flexible transbronchial needle aspiration for staging of bronchogenic carcinoma. Chest. 1983; 84:571-6. Google Scholar18. White CS, Templeton PA, Hasday JD. CT-assisted transbronchial needle aspiration: usefulness of CT fluoroscopy. AJR Am J Roentgenol. 1997; 169:393-4. Google Scholar Author, Article, and Disclosure InformationAuthors: Peter White Jr., MD; David S. Ettinger, MDAffiliations: The Johns Hopkins University School of Medicine Baltimore, MD 21287Dr. Ettinger: Johns Hopkins Oncology Center, 600 North Wolfe Street, Baltimore, MD 21287.Grant Support: In part by National Institutes of Health-National Cancer Institute grants 5P30CA06973-33 and 5P50CA58184-03 (Dr. Ettinger).Corresponding Author: Peter White Jr., MD, 720 Rutland Avenue, Ross Building 858, Division of Pulmonary and Critical Care Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21205.Current Author Addresses: Dr. White: 720 Rutland Avenue, Ross Building 858, Division of Pulmonary and Critical Care Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21205. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoEndoscopic Ultrasonography, Fine-Needle Aspiration Biopsy Guided by Endoscopic Ultrasonography, and Computed Tomography in the Preoperative Staging of Non-Small-Cell Lung Cancer: A Comparison Study Frank G. Gress , Thomas J. Savides , Alan Sandler , Kenneth Kesler , Dewey Conces , Oscar Cummings , Praveen Mathur , Steven Ikenberry , Sandy Bilderback , and Robert Hawes Endoscopic Ultrasonography, Fine-Needle Aspiration Biopsy Guided by Endoscopic Ultrasonography, and Computed Tomography in the Preoperative Staging of Non-Small-Cell Lung Cancer: A Comparison Study Frank G. Gress , Thomas J. Savides , Alan Sandler , Kenneth Kesler , Dewey Conces , Oscar Cummings , Praveen Mathur , Steven Ikenberry , Sandy Bilderback , and Robert Hawes Metrics Cited byExtraintestinal EndosonographyExtraintestinal Endosonography (including Celiac Block)EUS staging of primary lung carcinoma: are we ready for it?Cytologic approach to tumors of the tracheobronchial treeBronchoscopy and needle biopsy techniques for diagnosis and staging of lung cancerUtilidad de la punción aspirativa con aguja fina guiada por ultrasonografía endoscópica (USE-PAAF) en el diagnóstico de extensión del cáncer de pulmón de células no pequeñasEndoscopic ultrasound-guided fine needle aspiration for staging patients with carcinoma of the lungSurgery for Non-Small Cell Lung Cancer 15 October 1997Volume 127, Issue 8_Part_1Page: 643-645 ePublished: 15 August 2000 Issue Published: 15 October 1997 Copyright & PermissionsCopyright © 1997 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...