A Brugada-Pattern Electrocardiogram and Adrenal Insufficiency
Authors: Yasser Khalil, Sultan M. Siddique, Nghia T. Hoang
Journal: Annals of Internal Medicine (2010)

Letters21 December 2010A Brugada-Pattern Electrocardiogram and Adrenal InsufficiencyYasser Khalil, MD, Sultan M. Siddique, MD, and Nghia T. Hoang, DOYasser Khalil, MDFrom Lehigh Valley Health Hospital and Health Network, Allentown, PA 18103, and Hahnemann University Hospital, Philadelphia, PA 19102.Search for more papers by this author, Sultan M. Siddique, MDFrom Lehigh Valley Health Hospital and Health Network, Allentown, PA 18103, and Hahnemann University Hospital, Philadelphia, PA 19102.Search for more papers by this author, and Nghia T. Hoang, DOFrom Lehigh Valley Health Hospital and Health Network, Allentown, PA 18103, and Hahnemann University Hospital, Philadelphia, PA 19102.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-153-12-201012210-00016 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Background: The Brugada syndrome is characterized by right bundle branch block (RBBB) and ST-segment elevation in V1 to V3 with clinical symptoms due to polymorphic ventricular tachycardia or ventricular fibrillation. Observers have reported that a Brugada-pattern electrocardiogram (ECG) can be induced by several clinical conditions, but adrenal insufficiency has not been included among them.Objective: To describe a patient with adrenal insufficiency who had a Brugada-pattern ECG.Case Report: A 47-year-old man with a history of hypothyroidism and no coronary artery disease presented to our hospital with progressive weakness, dizziness, and weight loss of 4 weeks' duration. He was unable ...References1. Wilde AA, Antzelevitch C, Borggrefe M, Brugada J, Brugada R, Brugada P, et al; Study Group on the Molecular Basis of Arrhythmias of the European Society of Cardiology. Proposed diagnostic criteria for the Brugada syndrome. Eur Heart J. 2002;23:1648-54. CrossrefMedlineGoogle Scholar2. Ortega-Carnicer J, Benezet J, Ruiz-Lorenzo F, Alcázar R. Transient Brugada-type electrocardiographic abnormalities in renal failure reversed by dialysis. Resuscitation. 2002;55:215-9. CrossrefMedlineGoogle Scholar3. Kalra S, Iskandar SB, Duggal S, Smalligan RD. Fever-induced ST-segment elevation with a Brugada syndrome type electrocardiogram [Letter]. Ann Intern Med. 2008;148:82-4. LinkGoogle Scholar4. Yan GX, Antzelevitch C. Cellular basis for the Brugada syndrome and other mechanisms of arrhythmogenesis associated with ST-segment elevation. Circulation. 1999;100:1660-6. CrossrefMedlineGoogle Scholar5. McAlpine JK, Thomson JE. Myasthenia gravis and Schmidt syndrome. Postgrad Med J. 1988;64:787-8. CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Yasser Khalil, MD; Sultan M. Siddique, MD; Nghia T. Hoang, DOAffiliations: From Lehigh Valley Health Hospital and Health Network, Allentown, PA 18103, and Hahnemann University Hospital, Philadelphia, PA 19102.Disclosures: Dr. Siddique: Payment for lectures, including service on speakers bureaus: sanofi-aventis. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoFever-Induced ST-Segment Elevation with a Brugada Syndrome–Type Electrocardiogram Sumit Kalra , Said B. Iskandar , Sonia Duggal , and Roger D. Smalligan Metrics Cited byBrugada Phenocopy: New Terminology and Proposed Classification 21 December 2010Volume 153, Issue 12 Page: 849-851 Keywords Action potentials Cells Electrocardiography Potassium Right bundle branch block Right ventricle Sodium Sodium channels Ventricular fibrillation Ventricular tachycardia ePublished: 21 December 2010 Issue Published: 21 December 2010 Copyright & PermissionsCopyright © 2010 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...