A STUDY OF THE USE OF RADIOACTIVE GALLIUM IN MEDICINE
Authors: Frederick R. Lang
Journal: Annals of Internal Medicine (1951)

Article1 December 1951A STUDY OF THE USE OF RADIOACTIVE GALLIUM IN MEDICINEFREDERICK R. LANGFREDERICK R. LANGAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-35-6-1237 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptI. INTRODUCTIONThis study was initiated to determine whether or not radioactive gallium would prove to be of value as a method for radio-isotope tracer studies and/or as a therapeutic measure in the management of patients who have primary or metastatic malignancy of the bone. It was conducted conjointly in the U. S. Naval Medical Research Institute and in the Laboratory of the Radioactive Isotope Board, U. S. Naval Hospital, National Naval Medical Center, Bethesda, Maryland. Both of these activities are integral parts of the National Naval Medical Center, Bethesda, Maryland.The preliminary work on the metabolism and toxicity of...Bibliography1. Sollman T: Manual of pharmacology, 7th Ed., 1948, W. B. Saunders, Philadelphia. Google Scholar2. DudleyLevine HCMD: Determination of gallium in biological materials, J. Pharmacol. and Exper. Therap. 95: 487-493 (April) 1949. MedlineGoogle Scholar3. DudleyMaddoxLaRue HCGEHC: Studies of the metabolism of gallium, J. Pharmacol. and Exper. Therap. 96: (June) 1949. Google Scholar4. DudleyMaddox HCGE: Deposition of radio-gallium (Ga-72) in skeletal tissues, J. Pharmacol. and Exper. Therap. 96: (July) 1949. Google Scholar5. DudleyMunnHenry HCJIKE: Studies of the metabolism of gallium. II. Unpublished official report on file in Naval Medical Research Institute, National Naval Medical Center, Bethesda, Maryland, 1949. Google Scholar6. Rabuteau A: Recherches sur les effets des sel a de gallium, Compt. rend. Soc. de biol. 5: 310-314, 1883. Google Scholar7. SchwarzSicke LF: Über Gallium, Arch. Hyg. 100: 143-148, 1928. Google Scholar8. Levaditi C: La repartition du gallium dans l'organisme, Comp. rend. Acad. d. sc. 193: 117-119 (July 15) 1931. Google Scholar9. MeekHarroldMcCord SFGCCP: Toxicity of gallium, Indust. Med. 12: 7-9 (Jan.) 1943. Google Scholar10. DudleyLevine HCMD: Studies on the toxic action of gallium, Special Report on Project MM011-013 (Report No. 3), Naval Medical Research Institute, National Naval Medical Center, Bethesda, Maryland. Google Scholar11. DudleyLevine HCMD: Studies of the toxic action of gallium, J. Pharmacol. and Exper. Therap. 95: (April) 1949. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: MC U. S. Navy Annapolis, Maryland*Received for publication December 2, 1950.From U. S. Naval Hospital, Bethesda, Maryland. Submitted as thesis to the Faculty of the Graduate School of Medicine of the University of Pennsylvania toward the requirements for the degree of Doctor of Medical Science (D. Sc., Med.) for graduate work in Internal Medicine.The opinions or assertions contained herein are the private ones of the writer and are not to be construed as official or reflecting the views of the Navy Department or the Naval Service at large. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited by2 Clinically Useful Chelators of Tripositive ElementsThe interaction of gallium with biological systemsThe medical use of gallium radionuclides: A brief history with some commentsGallium-67 and indium-111 radiopharmaceuticalsGallium-67 and Indium-111 RadiopharmaceuticalsPurity tests of a 68Ge68Ga generatorEvaluation of a gallium-palladium-tin alloy for restorative dentistryGalliumChildhood cancer (tumors, leukemia, andHodgkin's disease) 1 December 1951Volume 35, Issue 6Page: 1237-1249KeywordsBoneGraduate medical educationResearch laboratoriesToxicity ePublished: 1 December 2008 Issue Published: 1 December 1951 PDF downloadLoading ...