Update in Pulmonary Disease
Authors: Catherine C. Peng, Sherrie L. Aspinall, Chester B. Good
Journal: Annals of Internal Medicine (2001)

Letters21 August 2001Update in Pulmonary DiseaseCatherine C. Peng, PharmD, Sherrie L. Aspinall, PharmD, BCPS, and Chester B. Good, MD, MPHCatherine C. Peng, PharmDVeterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA 15240 (Peng, Aspinall, Good)Search for more papers by this author, Sherrie L. Aspinall, PharmD, BCPSVeterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA 15240 (Peng, Aspinall, Good)Search for more papers by this author, and Chester B. Good, MD, MPHVeterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA 15240 (Peng, Aspinall, Good)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-135-4-200108210-00020 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:On the basis of an article by Destache and colleagues (1), Anzueto and Angel (2) report that third-line antibiotics may be more cost-effective for the management of acute exacerbations of chronic bronchitis. After reviewing the referenced article, we are disappointed that Anzueto and Angel make this statement, given its substantial clinical and cost implications. Destache and colleagues' article, an unblinded, retrospective study published as a supplement funded by Bayer (makers of ciprofloxacin), has several flaws that render it questionable.Destache and colleagues reported that third-line antibiotics (amoxicillin-clavulanate, azithromycin, and ciprofloxacin) improved clinical outcomes of acute exacerbations of ...References1. Destache CJ, Dewan N, O'Donohue WJ, Campbell JC, Angelillo VA. Clinical and economic considerations in the treatment of acute exacerbations of chronic bronchitis. J Antimicrob Chemother. 1999;43(Suppl A):107-13. [PMID: 10225580] CrossrefMedlineGoogle Scholar2. Anzueto A, Angel L. Update in pulmonary disease. Ann Intern Med. 2000;133:360-6. [PMID: 10979881] LinkGoogle Scholar3. Adams SG, Melo J, Luther M, Anzueto A. Antibiotics are associated with lower relapse rates in outpatients with acute exacerbations of COPD. Chest. 2000;117:1345-52. [PMID: 10807821] CrossrefMedlineGoogle Scholar4. Chen DK, McGeer A, de Azavedo JC, Low DE. Decreased susceptibility of Streptococcus pneumoniae to fluoroquinolones in Canada. Canadian Bacterial Surveillance Network. N Engl J Med. 1999;341:233-9. [PMID: 10413735] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Catherine C. Peng, PharmD; Sherrie L. Aspinall, PharmD, BCPS; Chester B. Good, MD, MPHAffiliations: Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA 15240 (Peng, Aspinall, Good) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoThe Tragic Events of April 1996 Jack Coulehan Update in Pulmonary Disease Antonio Anzueto and Luis Angel Metrics Cited byEqual Effectiveness of Older Traditional Antibiotics and Newer Broad-Spectrum Antibiotics in Treating Patients with Acute Exacerbations of Chronic Bronchitis 21 August 2001Volume 135, Issue 4Page: 301KeywordsAntibioticsChronic bronchitisHaemophilus influenzaeLungsPneumoniaPulmonary diseasesPulmonary functionRetrospective studiesStreptococcusTetracyclines ePublished: 21 August 2001 Issue Published: 21 August 2001 Copyright & PermissionsCopyright © 2001 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...