Membranous Glomerulonephritis: Virus-Like Inclusions in Glomerular Basement Membrane
Authors: ANIL K. MANDAL
Journal: Annals of Internal Medicine (1974)

Letters1 April 1974Membranous Glomerulonephritis: Virus-Like Inclusions in Glomerular Basement MembraneANIL K. MANDAL, M.D., F.A.C.P., DENNIS R. MASK, M.D., JOHN NORDQUIST, B.S., KATERINA S. CHRYSANT, M.D., ROBERT D. LINDEMAN, M.D., F.A.C.P.ANIL K. MANDAL, M.D., F.A.C.P.Search for more papers by this author, DENNIS R. MASK, M.D.Search for more papers by this author, JOHN NORDQUIST, B.S.Search for more papers by this author, KATERINA S. CHRYSANT, M.D.Search for more papers by this author, ROBERT D. LINDEMAN, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-80-4-554 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Although numerous reports have been published on viral-like particles inside glomerular endothelial cells in collagen diseases (1-3), only rarely have such particles been found in the glomerular basement membranes in patients with nephrotic syndrome (4, 5). We report here finding numerous viral-like inclusion bodies within the glomerular basement membranes in two additional patients with nephrotic syndrome.PATIENT 1A 45-year-old white woman was admitted in 1968 with a 7-year history of intermittent swelling of the body. Laboratory studies showed a 24-hour urine protein excretion of 6.6 g, a serum albumin of 2.7 g/100 ml, and a serum...References1. GYÖRKEYMINSINCOVICS FKJ: Systemic lupus erythematosus and myxovirus. N Engl J Med 280:333, 1969 CrossrefMedlineGoogle Scholar2. KAWANOMILLERKILLEMSTIEL KLP: Virus-like structures in lupus erythematosus. N Engl J Med 281:1228-1229, 1969 CrossrefMedlineGoogle Scholar3. NORTON W: Endothelial inclusions in active lesions of systemic lupus erythematosus. J Lab Clin Med 74:369-379, 1969 MedlineGoogle Scholar4. SMITHNORTHROP RR: Paramyxovirus-like structures in nephrotic syndrome. Am J Clin Pathol 56:97-103, 1971 CrossrefMedlineGoogle Scholar5. DEODHARMCCORMACKOSBORNE SLD: Unusual ultrastructural and immunologic findings in a case of membranous glomerular disease with renal vein thrombosis. Proceedings of the 31st Annual Meeting of the Electron Microscopy Society of America, edited by ARCENEAUX CJ. Baton Rouge, Louisiana, Claitor's Publishing Division, 1973, pp. 418-419 CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Medical Service Veterans Administration Hospital and Nephrology Section Department of Medicine University of Oklahoma Health Sciences Center Oklahoma City, Oklahoma 73104 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byCell membrane and coatGlomerular DiseaseAnatomic Pathology of Glomerulonephritis 1 April 1974Volume 80, Issue 4Page: 554-555KeywordsBasement membraneCollagen diseasesEndothelial cellsExcretionGlomerulonephritisInflammationResearch laboratoriesSerum albuminSerum proteinsUrine Issue Published: 1 April 1974 PDF downloadLoading ...