The Course of Pulmonary Function in Sarcoidosis
Authors: SAMUEL F. BOUSHY
Journal: Annals of Internal Medicine (1965)

Article1 May 1965The Course of Pulmonary Function in SarcoidosisSAMUEL F. BOUSHY, M.D., RAYMOND S. KURTZMAN, M.D., NEIL D. MARTIN, M.D., BENJAMIN M. LEWIS, M.D.SAMUEL F. BOUSHY, M.D.Search for more papers by this author, RAYMOND S. KURTZMAN, M.D.Search for more papers by this author, NEIL D. MARTIN, M.D.Search for more papers by this author, BENJAMIN M. LEWIS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-62-5-939 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSerial observations of the clinical course and of the chest X ray have been reported in large series of patients with sarcoidosis (1-3). Serial studies of pulmonary function in this disease are few (4) and the interval between observations short. Yet, studies of clinical and radiologic course cannot be extrapolated to supply this knowledge; patients whose X ray has cleared may have a low diffusing capacity (5). There is need, therefore, of additional studies on the course of pulmonary function in sarcoidosis in relation to clinical and radiological data. The present paper reports serial observations of 18 such patients over...References1. SMELLIEHOYLE HC: The natural history of pulmonary sarcoidosis. Quart. J. Med. 29: 539, 1960. Google Scholar2. NITTER L: Changes in the chest roentgenogram in Boeck's sarcoid of the lungs. Acta Radiol. (Stockholm) Supplement 105, 1953. Google Scholar3. ELLISRENTHAL KG: Pulmonary sarcoidosis: roentgen observations on the course of the disease. Amer. J. Roentgen. 88: 1070, 1962. Google Scholar4. SMELLIEAPTHORPMARSHALL HGHR: The effect of corticosteroid treatment on pulmonary function in sarcoidosis. Thorax 16: 87, 1961. CrossrefGoogle Scholar5. 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CrossrefMedlineGoogle Scholar12. NEEDHAMROGANMCDONALD CDMCI: Normal standards for lung volume, intrapulmonary gas-mixing and maximum breathing capacity. Thorax 9: 313, 1954. CrossrefMedlineGoogle Scholar13. KORYCALLAHANBORENSYNER RCRHGJC: The Veterans Administration-Army cooperative study of pulmonary function. I. Clinical spirometry in normal men. Amer. J. Med. 30: 243, 1961. CrossrefMedlineGoogle Scholar14. MCCLEMENTRENZETTIHIMMELSTEINCOURNAND JHADAA: Cardio pulmonary function in the pulmonary form of Boeck's sarcoid. Amer. Rev. Tuberc. 67: 153, 1954. Google Scholar15. MEAD J: Mechanical properties of lungs. Physiol. Rev. 41: 281, 1961. CrossrefMedlineGoogle Scholar16. BRISCOEDUBOIS WAAB: Relationship between airway resistance, airway conductance and lung volume in subjects of different age and body size. J. Clin. Invest. 37: 1279, 1958. CrossrefMedlineGoogle Scholar17. HOLMGRENSVANBORG AN: Studies on the cardio pulmonary function in sarcoidosis: I. Cases with bilateral hilar lymph node enlargement and radiographically clear lung fields. Acta. Med. Scand. Supplement 366: 7, 1961. Google Scholar18. SVANBORG N: Studies on the cardiopulmonary function in sarcoidosis: III. Cases with fibrosis of the lungs. Ibid., p. 75. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Detroit, MichiganFrom the Pulmonary Function Laboratory, Department of Medicine, and Department of Radiology, Wayne State University, and City of Detroit Receiving Hospital, Detroit, Mich.This study was supported by grant 5K6-HE-2182-03 from the Public Health Service Career Award Program, research grant HE-02379-08 from the National Heart Institute, U. S. Public Health Service, Bethesda, Md., and grants from the Michigan Heart Association and the Receiving Hospital Research Corporation.Requests for reprints should be addressed to Benjamin M. Lewis, M.D., Professor of Medicine, Department of Medicine, Wayne State University School of Medicine, 1400 Chrysler Expressway, Detroit, Mich. 48207. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited BySarcoidosisTratamiento de la sarcoidosis con corticoidesGas exchange at a given degree of volume restriction is different in sarcoidosis and idiopathic pulmonary fibrosisPrognostic Significance of Gallium Lung Scans in SarcoidosisExercise Testing in Interstitial Lung DiseasePulmonary SarcoidosisPulmonary Sarcoidosis: A Disease Characterized and Perpetuated by Activated Lung T-LymphocytesRONALD G. CRYSTAL, M.D., WILLIAM C. ROBERTS, M.D., GARY W. HUNNINGHAKE, M.D., JAMES E. GADEK, M.D., JACK D. FULMER, M.D., BRUCE R. 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WEG, M.D., F.A.C.P.Long-term study of pulmonary sarcoidosisSarcoidosis in childrenPulmonary Function in SarcoidosisManagement of patients with cor pulmonale—Acute and chronicCourse of pulmonary sarcoidosis with and without corticosteriod therapy as determined by pulmonary function studies 1 May 1965Volume 62, Issue 5Page: 939-955KeywordsFibrosisHeartHospital medicineMedical servicesPulmonary diseasesPulmonary functionResearch grantsResearch laboratoriesSarcoidosisThorax Issue Published: 1 May 1965 PDF DownloadLoading ...