Testosterone and Resistance Training in AIDS
Authors: Hosam K. Kamel
Journal: Annals of Internal Medicine (2001)

Letters3 July 2001Testosterone and Resistance Training in AIDSHosam K. Kamel, MDHosam K. Kamel, MDSaint Louis University School of Medicine; St. Louis, MO 63104 (Kamel)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-135-1-200107030-00027 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:There are two points of interest in the article by Grinspoon and colleagues (1), which examined the effects of testosterone supplementation on muscle mass and strength in patients with AIDS cachexia. First, all patients had normal free testosterone levels (that is, they were eugonadal). Second, the dosage of testosterone enanthate used (200 mg/wk) was twice the physiologic replacement dosage.Eight published randomized, controlled trials have examined testosterone supplementation in men at doses that produced physiologic serum concentrations and assessed the effects of such supplementation on muscle mass and strength. Results from these trials suggest that testosterone supplementation ...References1. Grinspoon S, Corcoran C, Parlman K, Costello M, Rosenthal D, Anderson E, et al . Effects of testosterone and progressive resistance training in eugonadal men with AIDS wasting. A randomized, controlled trial. Ann Intern Med. 2000;133:348-55. [PMID: 0010979879] LinkGoogle Scholar2. Young NR, Baker HW, Liu G, Seeman E. Body composition and muscle strength in healthy men receiving testosterone enanthate for contraception. J Clin Endocrinol Metab. 1993;77:1028-32. [PMID: 0008408450] MedlineGoogle Scholar3. Friedl KE, Dettori JR, Hannan CJ, Patience TH, Plymate SR. Comparison of the effects of high dose testosterone and 19-nortestosterone to a replacement dose of testosterone on strength and body composition in normal men. J Steroid Biochem Mol Biol. 1991;40:607-12. [PMID: 0001958561] CrossrefMedlineGoogle Scholar4. Bhasin S, Storer TW, Berman N, Callegari C, Clevenger B, Phillips J, et al . The effects of supraphysiologic doses of testosterone on muscle size and strength in normal men. N Engl J Med. 1996;335:1-7. [PMID: 0008637535] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Saint Louis University School of Medicine; St. Louis, MO 63104 (Kamel) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoEffects of Testosterone and Progressive Resistance Training in Eugonadal Men with AIDS Wasting Steven Grinspoon , Colleen Corcoran , Kristin Parlman , Madeline Costello , Dan Rosenthal , Ellen Anderson , Takara Stanley , David Schoenfeld , Belton Burrows , Doug Hayden , Nesli Basgoz , and Anne Klibanski Prospective Evaluation of Cardiac Risk Indices for Patients Undergoing Noncardiac Surgery Kenneth Gilbert , Brian J. Larocque , and Lawrence T. Patrick Testosterone and Resistance Training in AIDS Steven K. Grinspoon Metrics 3 July 2001Volume 135, Issue 1Page: 64-65KeywordsAIDSAdverse eventsAttentionBehaviorBenign prostatic hyperplasiaHematocritMusclesPatientsSafetyTestosterone ePublished: 3 July 2001 Issue Published: 3 July 2001 CopyrightCopyright © 2001 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...