tbuckley/cabot-search huggingface dataset:
Dynamic and Structural Features of a Case of Compulsive Neurosis as Revealed in Dreams
Authors: Harold L. Levitan
Journal: Psychotherapy and Psychosomatics (1976)

Several examples of the manifest dreams reported by a patient with a compuslive neurosis are presented. An outstanding feature of the dreams was the sudden shift of the dreamer's self-representation from the role of criminal to the role of policeman. This shift is thought to parallel the oscillation between unconscious instinctual gratification and conscious attempts at reparation which is the main dynamic feature of the compulsive neurosis in waking life. The shift of orientation of the self reflects the operation of early defense mechanisms against the sadistic impulse. It also portrays graphically an early stage in the internalization process which leads ultimately to the creation of the superego. The repetitive nature of the dreams indicated that the patient had become fixated at this particular point in the course of his psychic development. It is interesting to note that like the Rat Man this patient suffered from a chronically undescended testicle. The real defect in the sexual apparatus in both patients may have been a factor which favored regression of the libido from the genital stage to the anal-sadistic stage.
An enhanced International Prognostic Index (NCCN-IPI) for patients with diffuse large B-cell lymphoma treated in the rituximab era
Authors: Zheng Zhou, Laurie H. Sehn, Alfred W. Rademaker, Leo I. Gordon, Ann S. LaCasce, Allison Crosby-Thompson, Ann Vanderplas, Andrew D. Zelenetz, Gregory A. Abel, Maria A. Rodriguez, Auayporn Nademanee, Mark S. Kaminski, Myron S. Czuczman, Michael Millenson, Joyce Niland, Randy D. Gascoyne, Joseph M. Connors, Jonathan W. Friedberg, Jane N. Winter
Journal: Blood (2013)
Spontaneous Rupture of the Spleen in Primary Plasma Cell Leukemia Scintigraphic???Pathologic Correlation
Authors: G D KIENZLE, J STERN, A COOPERBERG, C A OSBORNE
Journal: Clinical Nuclear Medicine (1985)

Log in or Register Subscribe to journalSubscribe Get new issue alertsGet alerts Enter your Email address: Wolters Kluwer Health may email you for journal alerts and information, but is committed to maintaining your privacy and will not share your personal information without your express consent. For more information, please refer to our Privacy Policy. Subscribe to eTOC Secondary Logo Journal Logo All Articles Images Videos Podcasts Blogs Advanced Search Toggle navigation Subscribe Register Login Articles & Issues Current IssuePrevious IssuesPublished Online First Collections ACNM MeetingsCMECommunication in OrganizationCOVID-19Feedback and RewardsFrom the American College of Nuclear MedicineHighly Cited and Frequently Read ArticlesPlanning and Conducting Meetings EffectivelyQuality and Safety in Health CareRecruitment of New PhysiciansTips for Giving a Memorable PresentationTips for LeadersTips for Physicians in Getting the Right Job ACNM ArticlesACNM Website For Authors Submit a ManuscriptInformation for AuthorsLanguage Editing ServicesAuthor PermissionsLippincott® Preprints Journal Info About the JournalEditorial BoardAdvertisingOpen AccessSubscription ServicesReprintsRights and Permissions All Articles Images Videos Podcasts Blogs Advanced Search
Injury, Death, and Cholesterol
Authors: Peter Cummings
Journal: Annals of Internal Medicine (1994)

Letters1 November 1994Injury, Death, and CholesterolPeter Cummings, MD, MPH and Bruce M. Psaty, MD, PhDPeter Cummings, MD, MPHSearch for more papers by this author and Bruce M. Psaty, MD, PhDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-121-9-199411010-00029 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:Our meta-analysis of primary prevention trials of cholesterol-lowering interventions in men showed the relative risk for death from injury among treated men compared with that of controls to be 1.42 (95% CI, 0.94 to 2.15) [1]. Although Dr. Muldoon disagrees with our inclusion of the EXCEL trial [2] and exclusion of the Veterans Affairs trial [3], these choices are of little practical importance. Including the Veterans Affairs trial and excluding the EXCEL trial produces essentially the same estimate of effect, as reported in the second line of Dr. Muldoon's Table 1; that is, our findings are substantially in ...References1. Cummings P, Psaty BM. The association between cholesterol and death from injury. Ann Intern Med. 1994; 120:848-55. Google Scholar2. Bradford RH, Shear CL, Chremos AN, Dujovne C, Downton M, Franklin FA, et al. Expanded Clinical Evaluation of Lovastatin (EXCEL) study results. I. Efficacy in modifying plasma lipoproteins and adverse event profile in 8245 patients with moderate hypercholesterolemia. Ann Intern Med. 1993; 118:850-5. Google Scholar3. Dayton S, Pearce ML, Hashimoto S, Dixon WJ, Tomiyasu U. A controlled clinical trial of a diet high in unsaturated fat in preventing complications of atherosclerosis. Circulation. 1969; 39-40(Suppl II):1-63. Google Scholar4. Heady JA, Morris JN, Oliver MF. WHO clofibrate/cholesterol trial: clarifications (Letter). Lancet. 1992; 340:1405-6. Google Scholar5. Muldoon MF, Manuck SM, Matthews KM. Lowering cholesterol concentrations and mortality: a quantitative review of primary prevention trials. BMJ. 1990; 301:309-14. Google Scholar Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 November 1994Volume 121, Issue 9Page: 719-720KeywordsCholesterolConfidence intervalsIntent to treat analysisRelative risk Issue Published: 1 November 1994 CopyrightCopyright © 1994 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...
Vitamin Intake and Health: A Scientific Review
Authors: Michael J. Glade
Journal: JAMA (1991)

As understanding of the medicinal properties of individual nutrients accumulates and public interest in the pharmacologic use of purified nutrients increases, so do the opportunities for exaggerated claims, misleading marketing advice, and outright fraud. In response, groups such as the industryfunded Foundation for Innovation in Medicine have proposed that the pharmacologic status of nutrients be recognized by the creation of a new drug classification, "nutraceuticals," with the installation of appropriate regulatory measures. Other groups, such as the American Society for Parenteral and Enteral Nutrition and the American College of Nutrition, have cautioned against the naive adoption of nutraceuticals into the American pharmacopeia. In an atmosphere of misinformation, confusion, and controversy,<i>Vitamin Intake and Health</i>is intended as a scholarly primer on the therapeutic utility of vitamins in disease prevention and treatment. Such a volume would be welcome in an era when many in the health professions seem eager to embrace
Cutaneous Mycobacterium fortuitum infection mimicking lupus vulgaris
Authors: Y-C. Lin, H-C. Chiu, C-H. Hsiao, S-H. Jee, Y-H. Liao
Journal: British Journal of Dermatology (2002)

Summary We report a woman with a lupus vulgaris-like skin eruption caused by Mycobacterium fortuitum. The presence of mycobacteria was confirmed with tissue culture and also the detection of mycobacterial heat shock protein 65 (hsp65) DNA in the biopsy specimen. The eruption resolved after treatment with amikacin and clarithromycin. Lupus vulgaris-like lesions might be included in the clinical spectrum of infections caused by rapidly growing mycobacteria.
<i>Mycobacterium chelonae</i>Causing Otitis Media in an Ear-Nose-and-Throat Practice
Authors: Philip W. Lowry, William R. Jarvis, Arnold D. Oberle, Lee A. Bland, Ronald Silberman, Joseph A. Bocchini, Hazel D. Dean, Jana M. Swenson, Richard J. Wallace
Journal: New England Journal of Medicine (1988)

Seventeen cases of otitis media caused by Mycobacterium chelonae were detected among patients seen at a single ear-nose-and-throat (ENT) office (Office A) in Louisiana between May 5 and September 15, 1987. All the patients had a tympanotomy tube or tubes in place or had one or more tympanic-membrane perforations, with chronic otorrhea that was unresponsive to standard therapy with antimicrobial agents. Middle-ear exploration in six patients revealed abundant granulation tissue; multiple granulomas and acid-fast bacilli were demonstrated on a section of tissue from one patient with a nonhealing mastoidectomy incision. Thirteen of the 14 ear isolates obtained from patients seen in Office A had the same unusual pattern of high-level resistance to aminoglycosides. M. chelonae and other nontuberculous mycobacteria were recovered from several sources of water in Office A, as well as in another ENT office (Office B) in a neighboring city that was visited by the index patient. Only one additional case was detected in Office B during the same period. Otologic instruments in Office A were cleaned in an ultrasonic bath with tap water and a liquid detergent; the contents of the bath were changed only once weekly. Instruments in Office B were placed in boiling water between patient examinations. This outbreak establishes M. chelonae as an agent of otitis media and underscores the need for high-level disinfection or sterilization of ENT instruments between examinations to prevent the transmission of this organism to patients in the office setting. (N Engl J Med 1988; 319:978–82.)
Low-Energy Ventricular Defibrillation and Miniature Defibrillators
Authors: Richard S. Crampton
Journal: JAMA (1976)

<h3>To the Editor.—</h3> When discussing transthoracic ventricular defibrillation, Loeb (232:845, 1975; 235:144, 1976) and Tacker et al (235:144, 1976) overlooked both direct-current (DC) countershock using low-level electrical energy and miniature defibrillators. More than 35 years ago, Wiggers<sup>1</sup>showed that serial low-energy shocks expedite ventricular defibrillation. Recent experiments, corroborating and extending these earlier observations, indicate that only a limited critical mass of ventricle need be defibrillated for restoration of intrinsic cardiac pacemaker function.<sup>2</sup>In humans, prospective investigation of transthoracic defibrillation showed that the stored 200 watt-second (W-sec) DC shock provided an average 3.1 (1.8-4.0) W-sec/kg. This 200 W-sec shock eliminated primary ventricular fibrillation on the first shock in 73 and on the second shock in 7 of 80 cardiac patients. Two others needed higher energy levels for defibrillation.<sup>3</sup>Our early experience confirms this report (Table). Thus, 86 episodes of prospectively assessed human ventricular fibrillation responded to an average
Invasive fungal disease in patients treated for newly diagnosed acute leukemia
Authors: Sarah P. Hammond, Francisco M. Marty, Julie M. Bryar, Daniel J. DeAngelo, Lindsey R. Baden
Journal: American Journal of Hematology (2010)

Invasive fungal disease (IFD) is a significant cause of morbidity and mortality in patients undergoing treatment for acute leukemia (AL). Antifungal prophylactic strategies are associated with significant toxicities and cost. We performed a retrospective study of the incidence and risk factors for IFD among patients newly diagnosed with and treated for AL between January 1, 2004 and July 1, 2006. Patient follow up concluded January 1, 2007. Among 231 patients with newly diagnosed AL, 31 (13.4%) developed IFD by the end of follow up, 24 (10.4%) of whom developed IFD within the first 100 days after diagnosis of AL. The cumulative probability of developing IFD was 5.9% by 30 days and 11.1% at 100 days after AL diagnosis. Patients who had persistent leukemia after an initial course of induction chemotherapy were significantly more likely to develop IFD than those who did not have evidence of persistent leukemia (14/65 (21.5%) vs. 15/148 (10.1%), P = 0.03). In a time-dependent Cox model, the adjusted hazard ratio for developing IFD within the first 100 days of AL diagnosis based on the number of days of neutropenia in that period was 4.85 (95% confidence interval: 1.52, 15.4). Those patients with more days of neutropenia in the first 100 days after AL diagnosis, such as those who did not achieve remission after a first course of induction chemotherapy, were more likely to develop IFD.
Selection of Controls in Testing for Alcoholism-Reply
Authors: Michael J. Eckardt
Journal: JAMA (1982)

<h3>In Reply.—</h3> It is unlikely that hospital status explained our results, because inpatients in the alcoholism treatment program were ambulatory, and were attending group therapy and physical therapy, as well as participating in a number of other physical activities. Moreover, they walked to the clinical chemistry laboratory to have their blood drawn. The remaining concern of Dr Dufour and Mr Irving is our comparing results from two clinical laboratories that used the same multiple analysis instruments and the same chemistry methodologies, but employed different reference values. We acknowledge that this is a difficult problem and welcome the opportunity to clarify further the rationale for our approach. Clinical laboratories adjust manufacture-suggested reference values to take into account biases and variances inherent in a specific instrument, as well as unique characteristics of their patient population and other situations that might influence laboratory values. These considerations are demonstrated in our study by the
Cardiac Volume in Normal Children and Adolescents
Authors: QUANG X. NGHIEM, MELVYN H. SCHREIBER, LEONARD C. HARRIS
Journal: Circulation (1967)

Cardiac volume was determined by a simplified Rohrer-Kahlstorf method in 305 healthy children and adolescents. The ages ranged from birth to 19 years. Height and weight were comparable with normal growth standards. Race, sex, age, height, weight, and body surface area were studied for their value in predicting cardiac volume. Cardiac volume was different in males and females ( p &lt; 0.005) and was more closely predicted by weight than by body surface area. In this study body weight has been used as a single predictor of cardiac volume for both sexes. Normal values are presented and the limitations of the technique discussed. Serial cardiac volume plotted against weight and cardiothoracic ratio plotted against time were correlated with the clinical course in 27 children with pure rheumatic mitral insufficiency. Cardiac volume was found to be superior to the cardiothoracic ratio in reflecting the severity and prognosis of mitral insufficiency. After the cardiac volume had reached a level of 1,100 to 1,300 ml, the course was progressively downhill in 10 adolescents in the absence of evidence of rheumatic activity in most cases. That the course of rheumatic mitral insufficiency is essentially volume-dependent is a phenomenon of great interest which may be used to assess the severity of mitral regurgitation and its future course.
Flank Incisional Hernia Noted on Radionuclide Dynamic/Static Images
Authors: JAMES D. SLAVIN, HASSANALI KASSAMALI, RICHARD P. SPENCER, HAROLD D. HAWKINS
Journal: Clinical Nuclear Medicine (1989)

SLAVIN, JAMES D. JR. M.D.; KASSAMALI, HASSANALI M.D.; SPENCER, RICHARD P. M.D.,Ph.D.; HAWKINS, HAROLD D. M.D. Author Information
Biomarkers of splenic function in infants with sickle cell anemia: baseline data from the BABY HUG Trial
Authors: Zora R. Rogers, Winfred C. Wang, Zhaoyu Luo, Rathi V. Iyer, Eglal Shalaby-Rana, Stephen D. Dertinger, Barry L. Shulkin, John H. Miller, Bea Files, Peter A. Lane, Bruce W. Thompson, Scott T. Miller, Russell E. Ware
Journal: Blood (2011)
Optical Mammography Using Diffuse Optical Spectroscopy for Monitoring Tumor Response to Neoadjuvant Chemotherapy in Women with Locally Advanced Breast Cancer
Authors: Boudewijn E. Schaafsma, Martijn van de Giessen, Ayoub Charehbili, Vincent T.H.B.M. Smit, Judith R. Kroep, Boudewijn P.F. Lelieveldt, Gerrit-Jan Liefers, Alan Chan, Clemens W.G.M. Löwik, Jouke Dijkstra, Cornelis J.H. van de Velde, Martin N.J.M. Wasser, Alexander L. Vahrmeijer
Journal: Clinical Cancer Research (2014)

Diffuse optical spectroscopy (DOS) has the potential to enable monitoring of tumor response during chemotherapy, particularly in the early stages of treatment. This study aims to assess feasibility of DOS for monitoring treatment response in HER2-negative breast cancer patients receiving neoadjuvant chemotherapy (NAC) and compare DOS with tumor response assessment by MRI.Patients received NAC in six cycles of 3 weeks. In addition to standard treatment monitoring by dynamic contrast enhanced MRI (DCE-MRI), DOS scans were acquired after the first, third, and last cycle of chemotherapy. The primary goal was to assess feasibility of DOS for early assessment of tumor response. The predictive value of DOS and DCE-MRI compared with pathologic response was assessed.Of the 22 patients, 18 patients had a partial or complete tumor response at pathologic examination, whereas 4 patients were nonresponders. As early as after the first chemotherapy cycle, a significant difference between responders and nonresponders was found using DOS (HbO2 86% ± 25 vs. 136% ± 25, P = 0.023). The differences between responders and nonresponders continued during treatment (halfway treatment, HbO2 68% ± 22 vs. 110% ± 10, P = 0.010). Using DCE-MRI, a difference between responders and nonresponders was found halfway treatment (P = 0.005) using tumor volume measurement calculations.DOS allows for tumor response assessment and is able to differentiate between responders and nonresponders after the first chemotherapy cycle and halfway treatment. In this study, DOS was equally effective in predicting tumor response halfway treatment compared with DCE-MRI. Therefore, DOS may be used as a novel imaging modality for (early) treatment monitoring of NAC.
Physicians Married to Physicians
Authors: Miriam Greenberg
Journal: Annals of Internal Medicine (1994)

Letters15 April 1994Physicians Married to PhysiciansMiriam Greenberg, MD and Sheldon Greenberg, MDMiriam Greenberg, MDLong Island Jewish Medical Center; New Hyde Park, NY 11042Coney Island Hospital; Brooklyn, NY 11235Search for more papers by this author and Sheldon Greenberg, MDLong Island Jewish Medical Center; New Hyde Park, NY 11042Coney Island Hospital; Brooklyn, NY 11235Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-120-8-199404150-00030 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:As a two-physician couple, we have not regarded our fulfilling lifestyle as a “phenomenon” but rather have taken it for granted.The suggestion that physicians marry other physicians largely because of limited opportunities for socializing with others is flawed. The attraction is multifaceted. Physician couples at once delight in each other's successes, respect each other's work pressures, and appreciate each other's ideals.As the editors describe, two-physician couples face unique challenges. Although policies regarding coordination of schedules, child care, and maternity (and paternity) leave would be greatly desirable, few accommodations have been made for the decade-old influx ...REFERENCE1. Fletcher RH, Fletcher SW. Here come the couples (Editorial). Ann Intern Med. 1993; 119:628-30. Google Scholar Author, Article, and Disclosure InformationAuthors: Miriam Greenberg, MD; Sheldon Greenberg, MDAffiliations: Long Island Jewish Medical Center; New Hyde Park, NY 11042Coney Island Hospital; Brooklyn, NY 11235 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 15 April 1994Volume 120, Issue 8Page: 697KeywordsMedical services ePublished: 15 August 2000 Issue Published: 15 April 1994 Copyright & PermissionsCopyright © 1994 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
ON THE USE OF CHLOROFORM IN OPERATIONS ON THE EYE
Authors: W. Cooper
Journal: BMJ (1853)

J&w. 7, concerned in influencing the functions; of consciousness and volitioii, it is eiiually manifest that an anamiesaeo h el sels is precisely the onie calcutlated to dim-arm the narcotic of its dangerous properties.Butt for that anwmnic state, the cerebral capillaries ri-ight be goaded on by) a full dose of opium inito fatal comla.Thle niecessity of at hiealthyv amnoint of congestioni and conseqluent pressure, however es-senitial to the pr(Aluctliit of sleep, may-t be inferred also frtm(i)i cnsiderations regarding the nuitrititin of thte Orgain."The sleep of animials", D)r.Carpenter tells us, "1consists not iii a state or dtiminishled energy of the nt(tLriti cc funictions, hut in the cessation (if the seaisorial activity, dlependent upon a suispension of the funrctional power of certaini parts (if the nervous systCtti, during whichl there is reason to believe that the nutritive and( rej,arative oper'ations (it, those.
Prognostic and biological implications of genetic abnormalities in multiple myeloma undergoing autologous stem cell transplantation: t(4;14) is the most relevant adverse prognostic factor, whereas RB deletion as a unique abnormality is not associated with adverse prognosis
Authors: N C Gutiérrez, M V Castellanos, M L Martín, M V Mateos, J M Hernández, M Fernández, D Carrera, L Rosiñol, J M Ribera, J M Ojanguren, L Palomera, S Gardella, L Escoda, J C Hernández-Boluda, J L Bello, J de la Rubia, J J Lahuerta, J F San Miguel
Journal: Leukemia (2006)
Cross‐reactivity between terrestrial snails (<i>Helix species</i>) and house‐dust mite (<i>Dermatophagoides pteronyssinus</i>). II. <i>In vitro</i> study
Authors: L. Guilloux, D.‐A. Vuitton, M. Delbourg, A. Lagier, B. Adessi, C. R. Marchand, G. Ville
Journal: Allergy (1998)

Epidemiologic and in vitro data have shown that the association of housedust mite (HDM) allergy and snail allergy in the same patients was due to cross‐reactivity between HDM and snail allergenic components. However, the cross‐reacting allergen(s) have not yet been identified. In vitro reactivity of seven patients' sera to the various extracts and hemolymph of four different Helix snail species was analyzed by IgE detection on immunodots and Western blots. Cross‐reactivity between snails and Dermatophagoides pteronyssinus was assessed by immunodot and ELISA inhibition in two patients. Heterologous inhibition of the snail immunodot and ELISA was observed in one serum. Western blotting showed a specific binding on all four snail species extracts: molecular weights of snail allergens ranged from &lt;21 to 200 kDa. Marked individual differences were observed in the seven sera under study: most sera demonstrated IgE recognition of multiple bands, illustrating that no single allergen is responsible for cross‐reactivity between snail and mite. These results confirm that cross‐reactivity exists between snails of the Helix genus and HDM. This cross‐reactivity, involving more than a single allergen, may be of clinical significance in atopic patients allergic to D. pteronyssinus. The identity of the cross‐reacting allergens remains to be determined. Potential candidates include the thermostable minor allergens of D. pteronyssinus, tropomyosin and hemocyanin. Diseases, Environment.
Hypersensitivity Drug Reactions (HDR) In Latin America. Similarities and Differences Between Children and Adults
Authors: Ricardo Cardona-Villa, Edgardo J. Jares, Maximiliano Gómez, Luis Felipe C. Ensina, Mario Sánchez-Borges, Alfredo Arias Cruz, Carlos Serrano, Mabel Noemi Cuello, Ivan Cherrez, Andrea Zanacchi, Alicia De Falco, Silvana Monsell, Adolfo Salvatierra, Susana Barayazarra, Susana Diez-Zuloaga, Blanca Maria Morfin-Maciel, Paola Toche Pinaud, Sandra González Díaz, Juan F. Schuhl
Journal: Journal of Allergy and Clinical Immunology (2014)