Regression of Focal Nodular Hyperplasia After Discontinuation of Oral Contraceptives
Authors: DENNIS ROSS
Journal: Annals of Internal Medicine (1976)

Letters1 August 1976Regression of Focal Nodular Hyperplasia After Discontinuation of Oral ContraceptivesDENNIS ROSS, M.D., JORGA PINA, M.D., MEDO MIRZA, M.D., ALONSO GALVAN, M.D., LUCAS PONCE, M.D.DENNIS ROSS, M.D.Search for more papers by this author, JORGA PINA, M.D.Search for more papers by this author, MEDO MIRZA, M.D.Search for more papers by this author, ALONSO GALVAN, M.D.Search for more papers by this author, LUCAS PONCE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-85-2-203 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe development of hepatic adenomata in women taking oral contraceptives has recently been described. Thirty-five cases of focal nodular hyperplasia or benign hepatic adenomata—or hamartoma—have been reported in the literature. Our patient developed focal nodular hyperplasia of the liver after 5 years of oral contraceptive use.A 25-year-old Latin-American woman was healthy until 9 hours before her admission on 11 August 1974, when she experienced the gradual onset and progression of dull epigastric pain unrelieved by antacids. She vomited one time but denied any diarrhea or fever. The patient had been on norethindrone with mestranol (Ortho-Novum®) continuously since April 1968...References1. BAUMBOOKSTEINHOLTZ JJF: Possible association between benign hepatomas and oral contraceptives. Lancet 2:926-927, 1973 CrossrefMedlineGoogle Scholar2. CONTOSTAVLOS D: Benign hepatomas and oral contraceptives (letter). Lancet 2:1200, 1973 CrossrefMedlineGoogle Scholar3. STAUFFERLAPINSKIHONOLD JMD: Focal nodular hyperplasia of the liver and intrahepatic hemorrhage in young women on oral contraceptives. Ann Intern Med 83:301-306, 1975 LinkGoogle Scholar4. GOLDSTEINNEIMAN HH: Angiographic findings in benign liver cell tumors. Diagnostic Radiol 110:339-343, 1974 Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: DENNIS ROSS, M.D.; JORGA PINA, M.D.; MEDO MIRZA, M.D.; ALONSO GALVAN, M.D.; LUCAS PONCE, M.D.Affiliations: Wesley Medical Center Wichita, KS 67214 Wichita State University Branch of the University of Kansas Medical Center College of Health Wichita, KS 67214 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byEstrogen-Driven Growth of Focal Nodular Hyperplasia: Truth or Myth?Focal Nodular Hyperplasia (FNH) of the LiverFocal Nodular Hyperplasia (FNH) of the LiverComplete spontaneous regression of giant focal nodular hyperplasia of the liver: Magnetic resonance imaging evaluation with hepatobiliary contrast mediaTwo cases of near-complete regression of focal nodular hyperplasia of the liver: Case reports and review of the literatureTumors and Cysts of the LiverHepatic Neoplasms: Features on Grayscale and Contrast Enhanced UltrasoundFocal nodular hyperplasiaHepatocellular carcinoma in a patient with focal nodular hyperplasiaOral contraceptive use and focal nodular hyperplasia of the liverAdenoma and Focal Nodular HyperplasiaImaging of the Liver and Spleen MorphologyFocal Nodular Hyperplasia: Natural Course Observed with CT and MRIRegression of Focal Nodular Hyperplasia of the Liver After Oral Contraceptive DiscontinuationNatural history of focal nodular hyperplasia of the liver: An ultrasound studyDiagnosis and treatment of focal nodular hyperplasiaOral contraceptive-dependent growth of focal nodular hyperplasiaFocal nodular hyperplasia of the liver: results of treatment and options in management.Oral contraceptives and focal nodular hyperplasia of the liverThe fibrolamellar variant of hepatocellular carcinoma. Its association with focal nodular hyperplasiaBenign Tumors of the LiverResolution of a Contraceptive-Steroid-Induced Hepatic Adenoma with Subsequent Evolution into Hepatocellular CarcinomaSTUART C. GORDON, M.D., K. RAJENDER REDDY, M.D., ALAN S. LIVINGSTONE, M.D., LENNOX J. JEFFERS, M.D., EUGENE R. SCHIFF, M.D.Cancer risks and the contraceptive pill: What is the evidence after nearly 25 years of use?Oestrogen receptors in focal nodular hyperplasia of the liverHepatic tumors and oral contraceptives: Surgical managementSimultaneous Occurrence of Hepatic Adenoma and Focal Nodular Hyperplasia: Report of a Case and Review of the LiteratureHuman liver tumors in relation to steroidal usage.Hepatocellular Carcinoma in Women: Probable Lack of Etiologic Association with Oral Contraceptive SteroidsHuman Liver Neoplasia and Steroid ExposureHuman Liver Neoplasia and Steroid ExposureLiver Tumors and Steroid ExposurePrecursor stage of hepatocellular neoplasm following long exposure to orally administered contraceptivesEnzyme pattern and marker antigens in nodular “regenerative” hyperplasia of the liverStudies on the role of oral contraceptive use in the etiology of benign and malignant liver tumorsDrug-Induced Gastrointestinal DisordersMultiple adenomas of the liverRelation of steroids to liver oncogenesisHepatic Neoplasms Associated with Contraceptive and Anabolic SteroidsOral Contraceptive Associated Liver TumorsLiver Cell Adenoma Associated with Oral Contraceptive Hormone TherapyFamilial Liver-Cell Adenomas and Diabetes MellitusLiver adenoma associated with oral contraceptive pill administrationLebertumoren als Komplikation von OvulationshemmernSex hormonesDrug-induced gastrointestinal diseaseBenign hepatic lesions in women taking oral contraceptivesEpidemiological relationship between steroid hormones and liver lesionsHepatic Tumors: Possible Relationship to Use of Oral ContraceptivesBenign hepatic tumors and oral contraceptive pills 1 August 1976Volume 85, Issue 2Page: 203-204KeywordsDiarrheaFeversLiverOral contraceptive therapy ePublished: 1 December 2008 Issue Published: 1 August 1976 PDF downloadLoading ...