Hepatitis C from a Needlestick Injury
Authors: Leonard B. Seeff
Journal: Annals of Internal Medicine (1991)

Letters1 September 1991Hepatitis C from a Needlestick InjuryLeonard B. Seeff, MDLeonard B. Seeff, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-115-5-411_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editors: Transfusion-associated non-A, non-B hepatitis has recently been shown to result usually from infection with the hepatitis C virus (HCV) (1). Although we recognize that non-A, non-B hepatitis can follow smaller inoculum percutaneous exposure, such as a needlestick injury (2), data implicating HCV in this circumstance are lacking. I report an instance of HCV transmission by a needlestick injury incurred 18 years ago with persistence of circulating anti-HCV to the present.In 1972, a nurse injured her finger removing a hypodermic needle from a patient's arm. We were then doing a multicenter study to evaluate the protective efficacy...References1. Alter H, Purcell R, and Shih J. Detection of antibody to hepatitis C virus in prospectively followed transfusion recipients with acute and chronic non-A, non-B hepatitis. N Engl J Med. 1989;321:1494-1500. CrossrefMedlineGoogle Scholar2. Tabor E, Gerety R, and Drucker J. Transmission of non-A, non-B hepatitis from man to chimpanzee. Lancet. 1978;1:463-6. CrossrefMedlineGoogle Scholar3. Seeff L, Wright E, and Zimmerman H. Type B hepatitis after needlestick exposure: prevention with hepatitis B immune globulin. Ann Intern Med. 1978;88:285-93. LinkGoogle Scholar4. Tabor E, Seeff L, and Gerety R. Chronic non-A, non-B hepatitis carrier state: transmissible agent documented in one patient over a six-year period. N Engl J Med. 1980;303:139-43. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: Leonard B. 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