Adrenal Insufficiency as a Complication of the Acquired Immunodeficiency Syndrome
Authors: LOREN WISSNER GREENE
Journal: Annals of Internal Medicine (1984)

Brief Reports1 October 1984Adrenal Insufficiency as a Complication of the Acquired Immunodeficiency SyndromeLOREN WISSNER GREENE, M. D., WILLIAM COLE, M.D., JEFFREY B. GREENE, M.D., BRIAN LEVY, M.D., EDDIE LOUIE, M.D., BRUCE RAPHAEL, M.D., H. JOAN WAITKEVICZ, M.D., MANFRED BLUM, M.D.LOREN WISSNER GREENE, M. D.Search for more papers by this author, WILLIAM COLE, M.D.Search for more papers by this author, JEFFREY B. GREENE, M.D.Search for more papers by this author, BRIAN LEVY, M.D.Search for more papers by this author, EDDIE LOUIE, M.D.Search for more papers by this author, BRUCE RAPHAEL, M.D.Search for more papers by this author, H. JOAN WAITKEVICZ, M.D.Search for more papers by this author, MANFRED BLUM, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-101-4-497 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSince the acquired immunodeficiency syndrome was recognized in 1980, various malignancies, infections, and immunologic defects have been found in the affected population. Recently, adrenal necrosis was found at autopsy in ten patients who died of the syndrome (1). Seven of these patients had cytomegalovirus infiltration of the adrenal glands. Whether these patients had adrenal insufficiency is unknown, but this disorder was not suspected before their deaths and no chemical studies were done. A subsequent report described adrenal insufficiency preceding immunodeficiency in one patient (2). However, it remains to be ascertained whether Addison's disease is a feature of the syndrome.During...References1. TAPPER M, ROTTERDAM H, LERNER C, AL'KHAFAJI K, and SEITZMAN P. Adrenal necrosis in the acquired immunodeficiency syndrome. Ann Intern Med. 1984;100:239-41. LinkGoogle Scholar2. GUENTHNER E, RABINOWE S, VAN NIEL A, NAFTILAN A, and DLUHY R. Primary Addision's disease in a patient with the acquired immuno-deficiency syndrome. Ann Intern Med. 1984;100:847-8. LinkGoogle Scholar3. GUTTMAN P. Addison's disease: a statistical analysis of 566 cases and a study of the pathology. Arch Pathol. 1930;10:742-85. Google Scholar4. GREENE J, SIDHU G, and LEWIN S. Mycobacterium avium-intracellulare: a cause of disseminated life-threatening infection in homosexuals and drug abusers. Ann Intern Med. 1982;97:739-46. LinkGoogle Scholar5. EDWARDS O, COURTENAY-EVANS R, GALLEY J, HUNTER J, and TAIT A. Changes in cortisol metabolism following rifampicin therapy. Lancet. 1974; 2:549-51. 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GREENE, M.D.; BRIAN LEVY, M.D.; EDDIE LOUIE, M.D.; BRUCE RAPHAEL, M.D.; H. JOAN WAITKEVICZ, M.D.; MANFRED BLUM, M.D.Affiliations: New York University Medical Center Bellevue Hospital Manhattan Veterans Hospital New York Infirmary/Beekman Downtown Hospital New York, New York PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAdrenal Insufficiency: A Forgotten Diagnosis in HIV/AIDS Patients in Developing CountriesReferencesHuman immune deficiency virus (HIV) infection and the hypothalamic pituitary adrenal axisLow dose adrenocorticotropic hormone test and adrenal insufficiency in critically ill acquired immunodeficiency syndrome patientsThe effects of HIV-1 infection on endocrine organsAdrenal function in HIV infectionCYTOMEGALOVIRUSHISTOPLASMOSISAssessment of adrenal function by measurement of salivary steroids in response to corticotrophin in patients infected with human immunodeficiency virusEndocrine EmergenciesLong Term Adrenal Insufficiency Induces Skeletal Muscle Atrophy and Increases the Serum Levels of Active Form 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JACOBSON, M.D., JOHN MILLS, M.D.ADRENOCORTICAL LESIONS AND AIDSEndocrine disorders in men infected with human immunodeficiency virusMycobacterium avium-intracellulare and adrenal insufficiency in AIDSLife-Threatening Fluid and Electrolyte Abnormalities Associated with CancerPathology of the pituitary gland in patients with the acquired immune deficiency syndrome (AIDS)Adrenocortical insufficiency associated with Epstein-Barr virus infection in a patient with the Wiskott-Aldrich syndromeGeometric Universality in Brain Allosteric Protein Dynamics:.Hypoglycemia in Hospitalized PatientsHyporeninemic hypoaldosteronism associated with acquired immune deficiency syndromeAcquired Immunodeficiency Syndrome (AIDS)Lack of response to suramin in patients with AIDS and AIDS-related complexAcute Renal Failure in Critically Ill PatientsGastrointestinal Disease in AIDSThe Human Immunodeficiency Virus and the Adrenal MedullaCAROL D. WEISS, M.D.Suramin and Function of the Adrenal CortexCY A. STEIN, M.D., Ph.D., WAYNE SAVILLE, B.S., ROBERT YARCHOAN, M.D., S. BRODER, M.D., EDWARD P. GELMANN, M.D.Body composition studies in patients with the acquired immunodeficiency syndrome 1 October 1984Volume 101, Issue 4Page: 497-498KeywordsAIDSAdrenal glandsAutopsyImmunodeficienciesNecrosis ePublished: 1 December 2008 Issue Published: 1 October 1984 PDF downloadLoading ...