Renal Concentrating Defect in Sjögren's Syndrome
Authors: MELVIN KAHN
Journal: Annals of Internal Medicine (1962)

Article1 June 1962Renal Concentrating Defect in Sjögren's SyndromeMELVIN KAHN, M.D., ARTHUR D. MERRITT, M.D., MARTIN J. WOHL, M.D., JACK ORLOFF, M.D.MELVIN KAHN, M.D.Search for more papers by this author, ARTHUR D. MERRITT, M.D.Search for more papers by this author, MARTIN J. WOHL, M.D.Search for more papers by this author, JACK ORLOFF, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-56-6-883 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn the course of a recent study at the National Institutes of Health of the clinical and immunological abnormalities present in patients with Sjögren's syndrome (1-4), persistent hyposthenuria was observed in one of the subjects. In view of the systemic nature of this syndrome and the paucity of investigations of renal function (5, 6), further studies were performed in 8 patients with this disorder. The results of these studies of renal function are the subject of this report.MATERIALRenal function studies were performed in 8 patients with Sjögren's syndrome. Patients selected for study had symptomatic xerostomia and a random...References1. BLOCHWOHLSHIPOGLESBYBUNIM KJMJIIRBJJ: Sjögren's syndrome I. Serologic reactions in patients with Sjören's syndrome with and without rheumatoid arthritis. Arthritis Rheum. 3: 287, 1960. CrossrefMedlineGoogle Scholar2. BLOCHBUNIMWOHLZVAIFLER KJJJMJNJ: Unusual occurrence of multiple tissue component antibodies in Sjögren's syndrome. Trans. Ass. Amer. Physicians 73: 166, 1960. Google Scholar3. BUNIM JJ: A broader spectrum of Sjögren's syndrome and its pathogenetic implications. Ann. Rheum. Dis. 20: 1, 1961. CrossrefMedlineGoogle Scholar4. BLOCHWOHLOGLESBYSHIPBUNIM KJMJRBIIJJ: Sjögren's syndrome: an analysis of forty cases. Unpublished material. Google Scholar5. 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Author, Article, and Disclosure InformationAffiliations: Bethesda, MarylandFrom the Laboratory of Kidney and Electrolyte Metabolism of the National Heart Institute, the National Institute of Arthritis and Metabolic Diseases, and the National Institute of Dental Research, Bethesda, Maryland.This work was carried out while Dr. Kahn was a United States Public Health Service Postdoctoral Research Fellow, H.F.-10,390-C1.Requests for reprints should be addressed to Dr. Melvin Kahn, Department of Medicine, The Mount Sinai Hospital, 100th Street and Fifth Avenue, New York 29, New York. 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MONTGOMERY, M.D., F.A.C.P., CARL M. PEARSON, M.D., F.A.C.P., HUGH A. SMYTHE, M.D., F.R.C.P. (C), L. EMMERSON WARD, M.D., F.A.C.P., HOWARD J. WEINBERGER, M.D., F.A.C.P.Sjögren's syndromeSjögren's syndrome and its relation to connective tissue diseases 1 June 1962Volume 56, Issue 6Page: 883-895KeywordsAttentionClinical immunologyHeart diseasesHypertensionMedical servicesMetabolic disordersMuscle biopsiesRenal diseasesRenal physiologyResearch laboratories Issue Published: 1 June 1962 PDF DownloadLoading ...