tbuckley/cabot-search huggingface dataset:
Correction: The SI Symbol for "Litre"
Authors: G. VITAL DURAND
Journal: Annals of Internal Medicine (1987)

Letters and Corrections1 August 1987Correction: The SI Symbol for "Litre"G. VITAL DURANDG. VITAL DURANDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-107-2-265_3 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: The review by Young (1) on the implementation of SI units was thorough and didactic. It is a valuable contribution to improved communication among professionals and scientists. In the case of medicine, precise and specific information may prove lifesaving. Therefore it is unfortunate that a common mistake has been endorsed by the author. Litre is to be abbreviated as small l, not capital L (2, 3)....References1. YOUNG D. Implementation of SI units for clinical laboratory data: style specifications and conversion tables. Ann Intern Med. 1987;106:114-29. LinkGoogle Scholar2. Metric Practice Guide. American National Standards Institute, 1973: Z 210-1. Google Scholar3. Le Système International d'Unités (S.I.) Sèvres, France: Bureau International des Poids et Mesures;1977. Google Scholar1. . Standard for metric practice. Philadelphia: American Society for Testing and Materials; 1985:5. ASTM E 380-85. Google Scholar2. . The SI Manual in Health Care. 2nd ed. Ottawa: Metric Commission Canada; 1982:3. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Eli Lilly S.A. Geneva Switzerland PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 August 1987Volume 107, Issue 2Page: 265-265KeywordsScientists Issue Published: 1 August 1987 PDF DownloadLoading ...
DETERMINATION OF THE NORMAL RATE AND DURATIOIS OF MITOSIS IN HUMAN EPIDERMIS*
Authors: L. B. FISHER
Journal: British Journal of Dermatology (1968)

Journal Article DETERMINATION OF THE NORMAL RATE AND DURATIOIS OF MITOSIS IN HUMAN EPIDERMIS Get access L. B. FISHER L. B. FISHER Institute of Dermatology, London, England Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 80, Issue 1, 1 January 1968, Pages 24–28, https://doi.org/10.1111/j.1365-2133.1968.tb11901.x Published: 01 January 1968 Article history Accepted: 22 August 1967 Published: 01 January 1968
Gastrointestinal complications and esophageal stenosis after crack cocaine abuse
Authors: M. Appel-da-Silva, R. D'Incao, V. Antonello, E. Cambruzzi
Journal: Endoscopy (2013)

We describe the case of a 29-year-old man who presented to the emergency room complaining of sudden and severe abdominal pain for 3 days. Evaluation on admission revealed low blood pressure, an increased heart rate, and tachypnea. Abdominal examination revealed a positive Blumberg sign and an abdominal radiograph showed pneumoperitoneum requiring urgent surgical evaluation. In the operating room, the emergent exploratory laparotomy revealed an ischemic segment of the small bowel and a perforated gastric ulcer next to the prepyloric region. Following appropriate surgical management and a favorable course over 17 days in hospital, the patient was discharged.
Biologically based dose-response model for liver tumors induced by trichloroethylene.
Authors: C W Chen
Journal: Environmental Health Perspectives (2000)

The existing extensive laboratory data on trichloroethylene (TCE) and its two metabolites, dichloroacetic (DCA) and trichloroacetic (TCA), are used to explore the relationship among these three compounds. Under the hypothesis that these compounds induce liver tumors in mice through promotion of preexisting initiated cells, it is demonstrated that DCA alone could be responsible for all the response of carcinomas in liver of B6CF(1) mice. The focus of this paper is on how a plausible biological assumption could impact on low-dose risk estimates, rather than on the risk estimate per se. The findings suggest that low-dose risk estimates to humans would be overestimated unless the different background rates between mice and humans are properly accounted for.
Severe reflux disease is associated with an enlarged unbuffered proximal gastric acid pocket
Authors: A T Clarke, A A Wirz, J J Manning, S A Ballantyne, D J Alcorn, K E L McColl
Journal: Gut (2007)

An unbuffered pocket of highly acidic juice is observed at the gastric cardia after a meal in healthy subjects.To compare the postprandial acid pocket in healthy subjects and patients with severe reflux disease and define its position relative to anatomical and manometric landmarks.12 healthy subjects and 16 patients with severe reflux disease were studied. While fasted, a station pull-through was performed using a combined dual pH and manometry catheter. Position was confirmed by radiological visualisation of endoscopically placed radio-opaque clips. The pull-through study was repeated 15 min after a standardised fatty meal. Barium meal examination was performed before and following the meal.A region of unbuffered acid (pH <or=2) immediately distal to the proximal gastric folds was more frequent in reflux patients (23/32 studies) than in healthy subjects (11/24) (p<0.05). This unbuffered acid pocket was longer in the reflux patients than in the healthy subjects (median length 3 cm (range 1-15) vs 2 cm (range 1-5); p<0.05). The acid pocket extended proximally as far as the proximal gastric folds in the patients but stopped a median of 1.1 cm distal in healthy subjects (p = 0.005). In healthy subjects the acid pocket occupied the distal portion of the sphincter which opened postprandially, whereas in reflux patients it corresponded to the proximal displacement of the gastric folds--that is, hiatus hernia.This enlarged region of unbuffered postprandial acidic juice observed in the patients just below the gastro-oesophageal junction may contribute to the aetiology of severe reflux disease.
Blondes in Venetian Paintings, the Nine-Banded Armadillo, and Other Essays in Biochemistry
Authors: Nathaniel I. Berlin
Journal: JAMA (1995)

This is a delightful, well-written, readable collection of essays by Konrad Bloch, a 1964 Nobel Prize laureate and professor emeritus at Harvard. The subject matter can be characterized as a mini-text of the history of biochemistry, from its earliest times to the more recent era of molecular biology, which, not surprisingly, Bloch believes is really biochemistry in its true meaning and is a term that he does not fully accept. " '... important biochemical processes were discovered because of impure ATP The book begins with the intriguing essay "Blondes in Venetian Renaissance Paintings," which takes off from his observation of "the abundance of blondes [women not men] in Venetian Renaissance paintings." He found that women of the time rinsed their hair in "aqua bionda," for which there were a number of recipes, then sat in the sun wearing a hat designed to expose their hair to sunlight. Bloch concludes on chemical grounds
REMARKS ON THE NEED OF MORE EFFICIENT PROTECTION OF THE EYE AFTER CATARACT EXTRACTION, AND AN IMPROVED APPARATUS FOR THE PURPOSE.Read in the Section of Ophthalmology, at the Forty-second Annual Meeting of the American Medical Association, held at Washington, D. C., May 5-8, 1891.
Authors: G. E. FROTHINGHAM
Journal: JAMA (1891)

Perfect coaptation and support of the corneal flaps, freedom from any form of pressure that may cause gaping of the lips, or reopening of the wound, and perfect rest of the eye, are the objects mainly in view in adopting any form of dressing after the extraction of cataract. That any imperfect coaptation, or motion of the lips of the wound will interfere with its speedy and perfect union, and, that every reopening of the wound retards recovery and subjects the eye to dangers from infection and inflammatory reaction, are propositions so axiomatic that no one will dispute them. They seem to be universally received principles, though in practice we hardly take the precautions we ought to observe in order to secure our patients against these sources of danger. Mackenzie in his chapter on the after-treatment of extraction, writes as follows: "A careful assistant or experienced nurse, sitting constantly by
MEDICAL AND SURGICAL WORK AS A PRISONER OF WAR
Authors: A. T. I. Macdonald
Journal: BMJ (1919)

THBLTJOUSNAL 31 to a deviated nasal septum, a kink in tlle intestine; or microscopical clianges in tlle ovary." The letter kilieth but the Spirit givetlh life."Let us recognize that the old order lhas passed away from medicine, and the reign of tlhe New Spirit lhas begun.
Perfluoroperhydrophenanthrene versus perfluoro-n-octane in vitreoretinal surgery
Authors: Anat Loewenstein, Mark S Humayun, Eugene de Juan, Peter A Campochiaro, Julia A Haller
Journal: Ophthalmology (2000)

Purpose To compare two perfluorocarbon liquids, perfluoroperhydrophenanthrene (Vitreon) and perfluoro-n-octane (PFO), regarding (1) ease of removal at the time of surgery and (2) efficacy and safety. Design Retrospective, nonrandomized, comparative trial. Participants Two hundred sixty-four patients. Methods All medical records of patients who participated in either the Vitreon (n = 142) or the PFO (n = 122) multicenter trials at the Wilmer Eye Institute were reviewed. Patients in the two groups were compared with respect to presence and amount of postoperative perfluorocarbon. Safety and efficacy of the two perfluorocarbon liquids were evaluated in the subset of patients undergoing surgery for retinal detachment with PVR grade C or more, who had at least 6 months of postoperative follow-up (n = 46 in the Vitreon group and n = 55 in the PFO group). Best-corrected visual acuity, intraocular pressure, and status of the cornea, lens, and retina after 3, 6, and 12 months of follow-up were compared in the two groups. Main outcome measures Percentage of eyes with retained perfluorocarbon, final visual acuity, final retinal attachment rate. Results At the 6-month postoperative visit, retained Vitreon or PFO was detected in 8.4% and 4% of the eyes, respectively (P < 0.05). No statistically significant difference was found between the two perfluorocarbons in attachment rate or visual acuity after 6 and 12 months. After 6 months, the retina was attached in 71.7% of the eyes in which Vitreon was used and in 78.3% of the eyes in which PFO was used (P = 0.81). Visual acuity improved or remained stable in 80% of the Vitreon group eyes and in 74.5% of the PFO group eyes (P = 0.75). No statistically significant difference was found in final visual acuity or intraocular pressure between the two groups after 6 or 12 months. There was a tendency at the 12-month follow-up examination for the cornea to remain clearer in the Vitreon group (P = 0.01). Conclusions Although PFO was easier to visualize and remove completely from within the eye at the time of surgery, the efficacy in terms of retinal attachment and final visual outcome was similar between the Vitreon and PFO groups.
TCT-401 Detection by Intracoronary Near-infrared Spectroscopy of Lipid-rich Plaques within Remotely Implanted Stents
Authors: Mustafa Husaini, David Klungle, Mohsin Khan, Stacie M. Vanoosterhout, Margaret Chi, Zaahir Turfe, Sarah Dionne, Andrew Schmale, Ryan D. Madder
Journal: Journal of the American College of Cardiology (2014)
New prostate cancer drugs: few CV effects?
Authors: John Henahan
Journal: JAMA (1983)

Encouraging alternative approaches to orchiectomy and estrogen therapy for advanced prostatic cancer were highlighted in a series of presentations at the recent XIIIth International Congress of Chemotherapy in Vienna. Among the most prevalent malignant neoplasms worldwide, prostate cancer may be difficult to treat because it has often metastasized to bone and other organs by the time of diagnosis. One new investigational approach involves the use of synthetic analogs of gonadotropin-releasing hormone (GnRH), while the other employs drugs designed to destroy prostatic tumor tissue selectively. Most of the synthetic GnRH agents now under study result from substitution of a different amino acid in the 6 position of the naturally occurring GnRH decapeptide. Unlike natural GnRH, which is released in pulsatile fashion from the hypothalamus and acts through the pituitary to ultimately stimulate testosterone production by the gonads, the synthetic agonists apparently occupy the pituitary GnRH receptors continuously, desensitizing them and thereby
Screening for Ovarian Cancer
Authors: Daniel L. Clarke-Pearson
Journal: New England Journal of Medicine (2009)

A 56-year-old woman presents to her physician, requesting screening for ovarian cancer. She reports the recent death of a friend from ovarian cancer at the age of 65 years. The patient has no family history of ovarian or breast cancer. The physical examination, including pelvic and rectal examination, is normal. Should the physician recommend screening for ovarian cancer?
Increased fluid secretion after adenoviral-mediated transfer of the human aquaporin-1 cDNA to irradiated miniature pig parotid glands
Authors: Z. Shan, J. Li, C. Zheng, X. Liu, Z. Fan, C. Zhang, C.M. Goldsmith, R.B. Wellner, B.J. Baum, S. Wang
Journal: Molecular Therapy (2004)

The treatment of most head and neck cancer patients includes ionizing radiation (IR). Salivary glands in the IR field suffer irreversible damage. Previously, we reported that adenoviral (Ad)-mediated transfer of the human aquaporin-1 (hAQP1) cDNA to rat submandibular glands following IR restored salivary flow to near normal levels. It is unclear if this strategy is useful in larger animals. Herein, we evaluated AdhAQP1-mediated gene transfer after parotid gland IR (20 Gy) in the miniature pig. Sixteen weeks following IR, salivation from the targeted gland was decreased by >80%. AdhAQP1 administration resulted in a dose-dependent increase in parotid salivary flow to approximately 80% of pre-IR levels on day 3. A control Ad vector was without significant effect. The effective AdhAQP1 dose was 2.5 x 10(5) pfu/microl infusate, a dose that leads to comparable transgene expression in murine and minipig salivary glands. Three days after Ad vector administration little change was observed in clinical chemistry and hematology values. These findings demonstrate that localized delivery of AdhAQP1 to IR-damaged salivary glands increases salivary secretion, without significant general adverse events, in a large animal model.
Short stature and Helicobacter pylori infection in Italian children: prospective multicentre hospital based case-control study
Authors: G. Oderda, D Palli, C Saieva, E. Chiorboli, G Bona
Journal: BMJ (1998)

We thank the patients and general practitioners.Contributors: JMS designed and supervised the study, collected and analysed the data, interpreted the results, and reported the findings; he will act as guarantor for the paper.WJMacL and IJD designed and supervised the study, interpreted the results, and reported the findings.SI and SC
Proposed guidelines for diagnosing chronic active Epstein‐Barr virus infection
Authors: Motohiko Okano, Keisei Kawa, Hiroshi Kimura, Akihiro Yachie, Hiroshi Wakiguchi, Akihiko Maeda, Shosuke Imai, Shouichi Ohga, Hirokazu Kanegane, Shigeru Tsuchiya, Tomohiro Morio, Masaaki Mori, Shumpei Yokota, Shinsaku Imashuku
Journal: American Journal of Hematology (2005)

Abstract Since the initial report of unusual manifestations possibly associated with chronic active Epstein‐Barr virus (EBV) infection (CAEBV), nearly three decades have passed. During this period, reported cases with this entity have dramatically increased in the world. Additionally, recent development of diagnostic procedures, including molecular biological and immunological techniques, have provided us with the ability to define certain diseases, especially malignant disorders. Guidelines, derived mainly from the current literature and recent experiences with CAEBV in Japan, for diagnosing CAEBV are proposed to clarify this enigmatic disease. Am. J. Hematol. 80:64–69, 2005. © 2005 Wiley‐Liss, Inc.
An Update on the Diagnosis of Tuberculosis Infection
Authors: Luca Richeldi
Journal: American Journal of Respiratory and Critical Care Medicine (2006)

Section:ChooseTop of pageAbstract <<LIMITATIONS OF THE TUBERC...THE BLOOD ASSAYS FOR THE ...SENSITIVITY OF THE BLOOD ...SENSITIVITY OF THE BLOOD ...SPECIFICITY OF THE BLOOD ...OPERATIONAL ADVANTAGES OF...FEASIBILITY OF THE BLOOD ...IMPACT OF THE BLOOD TESTS...ReferencesCITING ARTICLES
Electric Treatment of Poliomyelitis—A Comment
Authors: Tom A. Williams
Journal: JAMA (1910)

To the Editor:—  Everyone must agree with Dr. Diller (The Journal, November 5, p. 1663) that electrical currents which produce pain and nervousness are harmful to children with poliomyelitis. But there is a difference of opinion as to whether or not any benefit is to be derived by passing electrical currents through the muscles which have ceased to respond on account of atrophy. Many observers believe that a galvanic current stimulates muscle growth. As to this, lacking precise data, my personal practice is dependent on such authorities as Duchenne, Bergonie, Zimmern and Erb, who recommend the daily use of the current even when there is no response to stimulation.  Be this as it may, the main advantage of galvanic stimulation of the muscles after poliomyelitis is the excitation of their physiologic contractility, a function otherwise unprovokable in muscles of which the nerve supply is destroyed. It should be obvious enough
Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia
Authors: Daniel J Hodson, Michelle L Janas, Alison Galloway, Sarah E Bell, Simon Andrews, Cheuk M Li, Richard Pannell, Christian W Siebel, H Robson MacDonald, Kim De Keersmaecker, Adolfo A Ferrando, Gerald Grutz, Martin Turner
Journal: Nature Immunology (2010)
Diagnosis of Fat Embolism
Authors: Karl W. Ascher
Journal: JAMA (1966)

To the Editor:—  Physicians and patients could benefit from ophthalmoscopy in cases of possible fat embolism. Evarts' discussion of the management of this condition (194: 899, 1965) omitted the diagnostically useful retinopathy of Purtscher, or traumatic retinal angiopathy. Whitish gray opaque patches in the retina are seen near blood vessels, sometimes accompanied by hemorrhages. These are observed two to four days after bone injuries, or postoperatively in cases in which there has been much handling of fat tissues. This retinopathy was described by Jacobi in 1868, later studied by the Austrian ophthalmologist Purtscher in 1910.  Size of lesions and degrees of visual impairment vary; transient small field defects may occur, but optic-nerve atrophy is not rare. The Viennese Urbanek (1934) correlated the clinical picture with histologically demonstrated fat emboli in retinal vessels, confirmed by Walsh in 1947.
The multidrug resistance-associated protein 3 (MRP3) is associated with a poor outcome in childhood ALL and may account for the worse prognosis in male patients and T-cell immunophenotype
Authors: Daniel Steinbach, Susann Wittig, Gunnar Cario, Susanne Viehmann, Angelika Mueller, Bernd Gruhn, Ralf Haefer, Felix Zintl, Axel Sauerbrey
Journal: Blood (2003)
A Study of the Late Effects of Total Body Irradiation
Authors: George L. Jordan, Vincent P. Collins, Robert A. Hettig
Journal: JAMA (1963)

THE INTRAVENOUS ADMINISTRATION of autologous marrow will prevent death following irradiation exposure which would be lethal in untreated animals.<sup>1,2</sup>The early effects of marrow transplants are well documented, but there is little information concerning the physiologic status in the late postirradiation period of large animals so treated. We have utilized fresh marrow, frozen marrow, and spleen as autologous transplants in the dog with success. The present report consists of physiologic studies in dogs surviving large doses of total body irradiation. <h3>Materials and Methods</h3> Mongrel dogs were irradiated with a 2 mv Van de Graaff x-ray generator. The half-value layer of the x-ray beam was 8 mm lead. The exposure dose was measured at the treating distance of 217 cm. Half of the exposure was delivered to the left side of the animal and half to the right. The dose rate was 15 to 17 roentgens/min so that treatment
Fatal bacteria granuloma after trauma: a new entity
Authors: T-W. Gao, C-Y. Li, X-D. Zhao, Y-F. Liu
Journal: British Journal of Dermatology (2002)

Summary In the past 20 years, more than 20 cases of a type of granulomatous disease have been noticed by dermatologists in different areas of China. The patients had these features in common: (i) the lesions followed a slight trauma to the face; (ii) they were spreading dark-red plaques without pus or ulceration; (iii) new lesions appeared near to or far from the original lesion; (iv) histopathology showed histiocytic granuloma; (v) the patients had severe headache and clouding of consciousness during the later stages of the disease; (vi) all patients died within 1·5–4 years; (vii) treatment with prednisone led to some healing of the lesions but accelerated death; and (viii) all patients were from rural areas. We examined the tissues from two similar patients by electron microscopy and identified two kinds of bacteria as a possible cause of the disease. One was an anaerobic actinomycete, the other was Staphylococcus capitis. The anaerobic actinomycete was sensitive to lincomycin (a forerunner of clindamycin). After a 5-month therapy with lincomycin, one patient survived. We infer that the cause of death is the unknown anaerobic actinomycete. Because the disease is very severe, we suggest the name 'fatal bacteria granuloma after trauma' to draw attention.