ACI-TIPI Clinical Trial
Authors: Harry P. Selker, John L. Griffith, Joni R. Beshansky
Journal: Annals of Internal Medicine (1999)

Letters21 September 1999ACI-TIPI Clinical TrialHarry P. Selker, MD, John L. Griffith, PhD, and Joni R. Beshansky, RN, MPHHarry P. Selker, MDNew England Medical Center; Boston, MA 02111 (Selker)New England Medical Center; Boston, MA 02111 (Griffith)New England Medical Center; Boston, MA 02111 (Beshansky)Search for more papers by this author, John L. Griffith, PhDNew England Medical Center; Boston, MA 02111 (Selker)New England Medical Center; Boston, MA 02111 (Griffith)New England Medical Center; Boston, MA 02111 (Beshansky)Search for more papers by this author, and Joni R. Beshansky, RN, MPHNew England Medical Center; Boston, MA 02111 (Selker)New England Medical Center; Boston, MA 02111 (Griffith)New England Medical Center; Boston, MA 02111 (Beshansky)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-131-6-199909210-00024 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSEWe agree with Weinfurt and colleagues that diagnostic technologies such as the ACI-TIPI should be evaluated in prospective controlled clinical trials. As emphasized by the National Institutes of Health National Heart Attack Alert Program (NHAAP) Diagnostic Technologies Working Group report (1), not only should such technologies be shown to have good diagnostic performance in relevant patients, but also they should be demonstrated to be safe and effective in actual use in clinical care. The latter is crucial, because even if a test's diagnostic performance is good in isolation, this may not translate into better physician decision making (2, ...References1. Selker HP, Zalenski RJ. An evaluation of technologies for detecting acute cardiac ischemia in the emergency department: a report of the NIH national heart attack alert program. Ann Emerg Med. 1997;29:13-87. CrossrefMedlineGoogle Scholar2. Lee TH, Pearson SD, Johnson PA, Garcia TB, Weisberg MC, Guadagnoli E, et al . Failure of information as an intervention to modify clinical management. A time-series trial in patients with acute chest pain. Ann Intern Med. 1995;122:434-7. LinkGoogle Scholar3. Selker HP. Coronary care unit triage decision aids: how do we know when they work? Am J Med. 1989;87:491-3. CrossrefMedlineGoogle Scholar4. An international randomized trial comparing four thrombolytic strategies for acute myocardial infarction. GUSTO investigators. N Engl J Med. 1993; 329:673-82. Google Scholar Author, Article, and Disclosure InformationAuthors: Harry P. Selker, MD; John L. Griffith, PhD; Joni R. Beshansky, RN, MPHAffiliations: New England Medical Center; Boston, MA 02111 (Selker)New England Medical Center; Boston, MA 02111 (Griffith)New England Medical Center; Boston, MA 02111 (Beshansky) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoUse of the Acute Cardiac Ischemia Time-Insensitive Predictive Instrument (ACI-TIPI) To Assist with Triage of Patients with Chest Pain or Other Symptoms Suggestive of Acute Cardiac Ischemia: A Multicenter, Controlled Clinical Trial Harry P. Selker , Joni R. Beshansky , John L. Griffith , Tom P. Aufderheide , Daniel S. Ballin , Sheilah A. Bernard , Steven G. Crespo , James A. Feldman , Susan S. Fish , W. Brian Gibler , Debra A. Kiez , Robert A. McNutt , Anne W. Moulton , Joseph P. Ornato , Philip J. Podrid , J. Hector Pope , Deeb N. Salem , Michael R. Sayre , and Robert H. Woolard Metrics 21 September 1999Volume 131, Issue 6Page: 477KeywordsClinical trialsDecision makingDrugsEmergency departmentFood and Drug AdministrationHealth care policyIschemiaMotivationMyocardial infarction ePublished: 15 August 2000 Issue Published: 21 September 1999 Copyright & PermissionsCopyright © 1999 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...