tbuckley/cabot-search huggingface dataset:
Echocardiographic predictors of nonrheumatic atrial fibrillation. The Framingham Heart Study.
Authors: S M Vaziri, M G Larson, E J Benjamin, D Levy
Journal: Circulation (1994)

BACKGROUND Although structural heart disease is often present in patients with nonrheumatic atrial fibrillation, the echocardiographic precursors of atrial fibrillation have not been reported previously. In this elderly, population-based cohort, our objective was to examine prospectively the echocardiographic predictors of nonrheumatic atrial fibrillation. METHODS AND RESULTS Subjects in the Framingham Heart Study were routinely evaluated with M-mode echocardiography; 1924 subjects, ranging in age from 59 to 90 years, comprised the population at risk. Cox proportional hazards modeling was used to analyze the association of selected echocardiographic features with atrial fibrillation risk after adjustment for age, sex, hypertension, coronary heart disease, congestive heart failure, diabetes, and valvular heart disease. During a mean follow-up interval of 7.2 years, 154 subjects (8.0%) developed atrial fibrillation. Multivariable stepwise analysis identified left atrial size (hazard ratio [HR] per 5-mm increment, 1.39; 95% confidence interval [CI], 1.14 to 1.68), left ventricular fractional shortening (HR per 5% decrement, 1.34; 95% CI, 1.08 to 1.66), and sum of septal and left ventricular posterior wall thickness (HR per 4-mm increment, 1.28; 95% CI, 1.03 to 1.60) as independent echocardiographic predictors of atrial fibrillation. For each of the echocardiographic predictors, risk increased progressively over successive quartiles. Moreover, risk increased markedly when highest-risk-quartile measurements for these features were present in combination; the cumulative 8-year age-adjusted atrial fibrillation rates were 7.3% and 17.0%, respectively, when one and two or more highest-risk-quartile features were present, compared with 3.7% when none was present. CONCLUSIONS In this elderly, population-based sample, left atrial enlargement, increased left ventricular wall thickness, and reduced left ventricular fractional shortening were predictive of risk for nonrheumatic atrial fibrillation. These echocardiographic precursors offer prognostic information beyond that provided by traditional clinical atrial fibrillation risk factors.
Coronary Computed Tomography of Syntax Score Reliability
Authors: Murat Uğur, Gökhan Çiçek, Mehmet Bozbay, Bayram Köroglu, Gurkan Karaca, Ahmet Murat, Eyyüp Tusun, Ezgi Kalay, Mehmet Eren
Journal: Journal of the American College of Cardiology (2013)
RESTORATION OF THE PELVIC STRUCTURES AFTER INJURY.Read in the Section of Obstetrics and Diseases of Women, at the Forty-second Annual Meeting of the American Medical Association, held at Washington, D. C., May 5-8, 1891.
Authors: HENRY O. MARCY
Journal: JAMA (1891)

1.<i>The Cervical Lesions of the Uterus</i>.—Little is required to add to the completeness of our knowledge to the present date, upon the surgical treatment of lacerations of the cervix uteri. Thanks to the labors of our distinguished countrymen, the late Dr. Sims and his early associate, Dr. Emmet, of New York, the limitations and advisability of the surgical repair of the cervical tissues of the uterus are generally well understood and accepted by the profession at large, as taught in the great surgical centres of the world. The restoration of the cervical tissues after the proper refreshment is greatly facilitated by the use of the Hagerdon needle, which pierces accurately and with comparative ease the thick, firm cervical tissue. The interrupted silver wire suture, so long used by the followers of these great masters, has been most advantageously supplanted by the continuous animal suture, since this at least equally
Influence of Rhythm and Anticoagulation upon the Incidence of Embolization Associated with Starr-Edwards Prostheses
Authors: THOMAS J. YEH, ISAM N. ANABTAWI, VICTOR E. CORNETT, ROBERT G. ELLISON
Journal: Circulation (1967)

The incidence of embolism following aortic and mitral valve replacement with Starr-Edwards prostheses has been analyzed and correlated with cardiac rhythm and anticoagulation. No embolism occurred in the aortic valve replacement group, regardless of use or nonuse of Coumadin. In the mitral group, the incidence of embolism during atrial fibrillation was approximately 1.7 times that during sinus rhythm. Coumadin prophylaxis was extremely effective. The incidence during non-anticoagulation was 40 times that during adequate anticoagulation, and seven times that during inadequate anticoagulation. Embolism occurred as late as 21 months after surgery, often shortly after termination of anticoagulation. Three of the four patients with emboli associated with bacterial endocarditis died. All nine patients with emboli not associated with infection survived, half without permanent sequelae.
"Ground Rounds" Series
Authors: Willard A. Wright
Journal: JAMA (1963)

<h3>To the Editor:</h3> —I was interested to discover in the Sept 21 issue ofThe Journal(vol 185, adv p 31) that six leading researchers in diabetes were to appear on the 11th program of the "Ground Rounds" series on Oct 2. I was not in New York on that date, but would appreciate your letting me know when the next "Ground Rounds" are available, as I would like to be on hand for my share of the hamburger.
Cephalothin Neurotoxicity in Renal Failure
Authors: MING-JIANG WU
Journal: Annals of Internal Medicine (1978)

Letters and Corrections1 September 1978Cephalothin Neurotoxicity in Renal FailureMING-JIANG WU, M.D., THOMAS A. NARSETE, M.D., JOHN L. HUSSEY, M.D., ARVIN B. WEINSTEIN, M.D., SUNG-FENG WEN, M.D.MING-JIANG WU, M.D.Search for more papers by this author, THOMAS A. NARSETE, M.D.Search for more papers by this author, JOHN L. HUSSEY, M.D.Search for more papers by this author, ARVIN B. WEINSTEIN, M.D.Search for more papers by this author, SUNG-FENG WEN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-89-3-429_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: In a recent article, "Drug-Related Syndromes in Clinical Nephrology", Bennett, Plamp, and Porter (1) pointed out that high-dose penicillin may produce seizures, altered mental state, and myoclonic jerking in uremic patients. We would like to add that another group of widely used antibiotics, the cephalosporins, can cause a similar syndrome. We recently saw a patient who developed severe encephalopathy due to accumulation of cephalothin.A 46-year-old white man with uremia received intravenous cephalothin, 4 to 5 g/day, after bilateral nephrectomy for infection in polycystic kidneys. During surgery 6 g of cephalothin was instilled in the abdominal cavity....References1. BENNETTPLAMPPORTER WCG: Drug-related syndromes in clinical nephrology. Ann Intern Med 87:582-590, 1977 LinkGoogle Scholar2. VIANNAKAYE ND: Penetration of cephalothin into the spinal fluid. Am J Med Sci 254:216-220, 1967 CrossrefMedlineGoogle Scholar3. BALLINGALTURPIE DA: Cephaloridine toxicity. Lancet 2:835-836, 1967 CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: MING-JIANG WU, M.D.; THOMAS A. NARSETE, M.D.; JOHN L. HUSSEY, M.D.; ARVIN B. WEINSTEIN, M.D.; SUNG-FENG WEN, M.D.Affiliations: Departments of Medicine and Surgery University of Wisconsin Center for Health Sciences 1300 University Avenue; Madison, WI 53706 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAntiinfective Agents Affecting Cognition: A ReviewANTIBIOTIC-INDUCED CONVULSIONSPenicillins, cephalosporins and tetracyclines 1 September 1978Volume 89, Issue 3Page: 429-429KeywordsAntibioticsBrain diseasesDrugsEpileptic seizuresMyoclonusNephrectomyNephrologyPenicillinPolycystic kidney diseaseRenal failure ePublished: 1 December 2008 Issue Published: 1 September 1978 PDF downloadLoading ...
Monitoring and Regulating Clinical Software
Authors: Eta S. Berner
Journal: Annals of Internal Medicine (1998)

Letters1 August 1998Monitoring and Regulating Clinical SoftwareEta S. Berner, EdDEta S. Berner, EdDUniversity of Alabama at Birmingham; Birmingham, AL 35294Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-129-3-199808010-00023 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Drs. Miller and Gardner and the organizations they represent are to be commended for developing guidelines for monitoring the performance of medical software [1]. Using the concepts of risk to the patient and the opportunity for competent clinician intervention to determine the stringency of the regulation and monitoring is a reasonable way to frame the recommendations. However, in allowing less strict regulation of systems in which a competent clinician has the opportunity to override the system, the authors assume that clinicians will routinely review the system output and will accurately recognize when to ignore the software's suggestions. ...References1. Miller RA, Gardner RM. Summary recommendations for responsible monitoring and regulation of clinical software systems. The American Medical Informatics Association, the Computer-based Patient Record Institute, the Medical Library Association, the Association of Academic Health Science Libraries, the American Health Information Management Association, and the American Nurses Association. Ann Intern Med. 1997; 127:842-5. Google Scholar Author, Article, and Disclosure InformationAffiliations: University of Alabama at Birmingham; Birmingham, AL 35294 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 August 1998Volume 129, Issue 3Page: 254KeywordsSystematic reviews ePublished: 15 August 2000 Issue Published: 1 August 1998 Copyright & PermissionsCopyright © 1998 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
The University of Texas Southwestern Medical School: Medical Education in Dallas, 1900-1975
Authors: Edward S. Petersen
Journal: JAMA (1977)

This book, representing much more than the internal development of the Southwestern Medical School, is a thoughtful study of the origins of medical education in the Dallas area, in the context of the social and political background. It begins with a fascinating picture of the Dallas medical and community scene at the turn of the century. In 1900, the first reasonably identifiable medical school in Dallas, the University of Dallas Medical School, was incorporated. In 1901, Dr E. H. Cary became its dean, and much of the remainder of the book describes his remarkable vision and creative ability. Aware of the importance of an affiliation with a university and a teaching hospital, he arranged this with Baylor Medical College in 1903 and with the Parkland Hospital in 1913. In 1920, Dr Cary resigned and turned to other interests, but these fortunately included the chartering of the Southwestern Medical Foundation in
PTH-045 Integrated Alcohol And Hepatology Mdt: Reducing Alcohol-related Hospital Admission And Attendance
Authors: K Mannix, K Patterson, L Richardson, S puravady, L Owens, P Richardson
Journal: Gut (2014)

<h3>Introduction</h3> In 2010 a joint position paper on behalf of British Society of Gastroenterology, the Alcohol Health Alliance UK, and the British Association for Study of the Liver highlighted that the most deprived lifestyle groups have up-to 15 times greater alcohol‐specific mortality and up to 10 times greater alcohol‐specific admissions to hospital. It therefore recommended that each acute hospital should develop a multidisciplinary approach to the care and management of people attending or admitted to hospital with an alcohol-related cause<sup>.1</sup> <h3>Methods</h3> We conducted a notes review of all patients attending or admitted to the hospital on more than 6 occasions in the previous 6 months. We also complied 3 in-depth case studies of our most frequent attenders. We investigated the reason for admission including medical and social confounders. We then looked at the range and number of medical and social disciplines involved in their care, discharge planning and aftercare. We spoke to our patients about why they had chosen to attend hospital and what they felt could be provided as an alternative. We developed an electronic early warning system to inform the Alcohol Team when a patient was admitted. This triggered referral to our integrated alcohol and hepatology consultant led MDT <h3>Results</h3> Our investigations showed that the majority of patients had a range of support including key workers from a variety of voluntary agencies, housing agencies, GP’s, primary care alcohol specialist nurses, social workers, homeless outreach, and specialist medical consultants from psychiatry to hepatology. However, much of this work was happening in isolation and was at times conflicting with no one organisation or professionals supporting or mapping out the patients journey. Importantl, y, the patients were unclear where to go for what, and were often utilising the ED as a failsafe when they were unsure or troubled. The MDT is a vehicle to ensure that the patient gets the right treatment at the right time by the right person; which has helped our patients better understand their care pathways and their aims. This has resulted in a significant reduction in hospital attendance and admission for this small but significant patient group. <h3>Conclusion</h3> An MDT for alcohol-related admissions augments and centralises the expertise of health and social care partners in the development of truly patient centred shared plans of care. This leads to hospital admission only when appropriate and necessary <h3>Reference</h3> 1 Moriarty K. A Joint Position Paper on behalf of the British Society of Gastroenterology, Alcohol Health Alliance UK, British Association for Study of the Liver – ALCOHOL-RELATED DISEASE Meeting the challenge of improved quality of care and better use of resources. 2010 <h3>Disclosure of Interest</h3> None Declared.
41 THE SODIUM IODIDE SYMPORTER ENHANCES CELL MIGRATION AND INVASION
Authors: C. Lacoste, J. Herve, N. Moniaux, F. Faitot, A. Dos Santos, Y. Valogne, M. Gigou, R. Montjean, B. Grosse, O. Dorseuil, D. Samuel, D. Cassio, C. Brechot, F. Jamila
Journal: Journal of Hepatology (2010)
A Note to His Doctor
Authors: Kevin Hadduck
Journal: JAMA (2014)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Scintigraphic Evaluation with Tc-99m MDP and Ga-67 Citrate in a Case of Pediatric T-Cell Lymphoma
Authors: JOSE E. RIVERA-RODRIGUEZ, ANA A. RODRIGUEZ, GOTTLIEB L. TURNBULL, ALBERT J. MORENO
Journal: Clinical Nuclear Medicine (1992)

Skeletal scintigraphy in patients with lymphoma typically reveals multiple subtle lesions with variable involvement of the axial and appendicular skeleton. The distribution of skeletal lesions in non-Hodgkins lymphoma in previous reports has shown the axial skeleton to be involved in 79% of cases, as opposed to 21% involvement of the appendicular skeleton. A case of non-Hodgkins lymphoma (T-cell type) in a 6-year-old girl is presented, revealing exclusive involvement of the appendicular skeleton and sparing of the axial skeleton.
Children request teaching when asking for names of objects
Authors: Sidney Strauss, Margalit Ziv
Journal: Behavioral and Brain Sciences (2001)

We propose that in addition to children's requests for word names being a reflection of an understanding of the referential nature of words, they may also be requests for adult's teaching. These possible requests for teaching among toddlers, along with other indications, suggest that teaching may be a natural cognition that may be related to the development of theory of mind.
Protein-tyrosine kinase Syk is required for pathogen engulfment in complement-mediated phagocytosis
Authors: Yuhong Shi, Yumi Tohyama, Tomomi Kadono, Jinsong He, S. M. Shahjahan Miah, Ryoichi Hazama, Chisato Tanaka, Kaoru Tohyama, Hirohei Yamamura
Journal: Blood (2006)
Percutaneous transatrial mitral commissurotomy: Immediate and intermediate results
Authors: Ramesh Arora, Gurcharan Singh Kalra, Goddu Sree Ramachandra Murty, Vijay Trehan, Neeraj Jolly, Jagdish Chander Mohan, Kamal Kumar Sethi, Madhuri Nigam, Mohammad Khalilullah
Journal: Journal of the American College of Cardiology (1994)
CAN LATE GADOLINIUM ENHANCEMENT IN PULMONARY HYPERTENSION PREDICT ADVERSE CLINICAL EVENTS? A CMR SINGLE CENTER STUDY
Authors: Siva Kumar Soma, Vishal Goyal, Mark Doyle, Srinivas Murali, Diane Vido, Raymond Benza, George Sokos, Vikas Rathi, Robert Biederman
Journal: Journal of the American College of Cardiology (2012)
PROGNOSIS IN FRONTAL LOBOTOMY BY USE OF THE MALAMUD RATING SCALE
Authors: WALTER FREEMAN
Journal: American Journal of Psychiatry (1953)

More than 1,000 lobotomized patients were graded according to level of achievement after convalescence had been completed, and their preoperative rating by the Malamud scale was studied in order to determine what factors were of good and bad omen. Favorable indications appeared in the fields of anxiety, obsessive thinking, and self-directed violence, while unfavorable indications appeared in the fields of hallucinations and delusions, scattered thought processes, and externally directed violence. The apparent paradox was disclosed that patients came to operation most frequently because of the latter phenomena. Since the objective of psychosurgery is to relieve overwhelming suffering, anything gained above this, as far as level of achievement is concerned, makes the operation even more worth while. The surgeon and the psychiatrist, working together, can select patients who will give almost any desired level of achievement. From the practical standpoint, the Malamud rating scale offers a modest predictive criterion for the selection of patients for psychosurgery.
Current Perspectives on Statins
Authors: David J. Maron, Sergio Fazio, MacRae F. Linton
Journal: Circulation (2000)

Abstract —Statins (HMG-CoA reductase inhibitors) are used widely for the treatment of hypercholesterolemia. They inhibit HMG-CoA reductase competitively, reduce LDL levels more than other cholesterol-lowering drugs, and lower triglyceride levels in hypertriglyceridemic patients. Statins are well tolerated and have an excellent safety record. Clinical trials in patients with and without coronary heart disease and with and without high cholesterol have demonstrated consistently that statins reduce the relative risk of major coronary events by ≈30% and produce a greater absolute benefit in patients with higher baseline risk. Proposed mechanisms include favorable effects on plasma lipoproteins, endothelial function, plaque architecture and stability, thrombosis, and inflammation. Mechanisms independent of LDL lowering may play an important role in the clinical benefits conferred by these drugs and may ultimately broaden their indication from lipid-lowering to antiatherogenic agents.
Hyperoxaluria and Bowel Disease
Authors: William H. Admirand
Journal: New England Journal of Medicine (1972)

Recurrent calcium oxalate nephrolithiasis is a frequent and serious complication in patients with disease or resection of the distal ileum. Hofmann et al. first noted that renal calculi formation in these patients was associated with excessive urinary excretion of oxalate.1 , 2 They suggested that failure to absorb conjugated bile salts in the distal ileum leads to increased quantities of glycine-conjugated bile salts in the colon, where bacteria can split off the glycine moiety and deaminate it to glyoxylate (the immediate precursor of oxalate). The glyoxylate might then be absorbed from the colon and serve as substrate for hepatic oxalate formation, resulting . . .
On the Physical Death of Jesus Christ
Authors: Rustin Berlow
Journal: JAMA (1986)

<h3>To the Editor.—</h3> I was astonished to read the article entitled "On the Physical Death of Jesus Christ."<sup>1</sup>It purported to "offer additional insight" based on "knowledge of science and medicine not available in the first century." I feel compelled to respond to at least a few points. I wonder about the propriety of this work appearing in this journal. The use of the name "Jesus Christ" has a specific<i>theological</i>connotation, namely, that Jesus is the Christ, or Messiah (ie, savior). This is a point fundamental to Christian belief; it is not merely a name but also an explicit claim. I was surprised to find it used in the title of the article. The authors admit that a major problem with attempting any analysis is that "the credibility of any discussion of Jesus' death will be determined primarily by the credibility of one's sources."<sup>1</sup>The authors were
Oxytocin infusion during second stage of labour in primiparous women using epidural analgesia: a randomised double blind placebo controlled trial.
Authors: N. J. Saunders, H. Spiby, L. Gilbert, R. B. Fraser, J. M. Hall, P. M. Mutton, A. Jackson, D. K. Edmonds
Journal: BMJ (1989)

To determine whether the high rate of forceps delivery associated with the use of epidural analgesia could be reduced through giving an intravenous infusion of oxytocin during the second stage of labour.A randomised, double blind, placebo controlled trial.Delivery suites in three hospitals.226 Primiparous women with adequate epidural analgesia in whom full dilatation of the cervix had been achieved without prior stimulation with oxytocin.An infusion of oxytocin or placebo starting at the diagnosis of full cervical dilatation at an initial dose rate of 2 mU/min increasing to a maximum of 16 mU/min.The outcome of labour was assessed in terms of the duration of the second stage, mode of delivery, fetal condition at birth, postpartum blood loss, and the incidence of perineal trauma.Treatment with oxytocin was associated with a shorter second stage (p = 0.01), a reduction in the number of non-rotational forceps deliveries (p = 0.03), and less perineal trauma (p = 0.03) but was not associated with any reduction in the number of rotational forceps deliveries performed for malposition of the occiput. No adverse effects on fetal condition at birth or in the early puerperium were seen in association with the use of oxytocin.The use of an oxytocin infusion may reduce the high rate of operative delivery associated with epidural analgesia provided that the fetal occiput is in an anterior position at the onset of the second stage of labour but within the dose range studied does not seem to correct malposition of the fetal occiput.