An Abnormal Lipoprotein in the Serum of Uremic Patients Maintained on Chronic Hemodialysis
Authors: Nicholas M. Papadopoulos, William Z. Borer, Ronald J. Elin, Louis H. Diamond
Journal: Annals of Internal Medicine (1980)

Brief Reports1 May 1980An Abnormal Lipoprotein in the Serum of Uremic Patients Maintained on Chronic HemodialysisNICHOLAS M. PAPADOPOULOS, Ph.D., WILLIAM Z. BORER, M.D., RONALD J. ELIN, M.D., Ph.D., LOUIS H. DIAMOND, M.D.NICHOLAS M. PAPADOPOULOS, Ph.D.Search for more papers by this author, WILLIAM Z. BORER, M.D.Search for more papers by this author, RONALD J. ELIN, M.D., Ph.D.Search for more papers by this author, LOUIS H. DIAMOND, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-92-5-634 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptPremature coronary heart disease resulting from accelerated atherosclerosis ranks as a major cause of death among uremic patients who are undergoing chronic hemodialysis (1). Increased concentrations of serum triglycerides (2) and low serum concentrations of highdensity (HD) lipoprotein-cholesterol have been reported in patients with end-stage renal disease treated with chronic maintenance hemodialysis (3, 4). The authors of these reports have suggested that the premature cardiovascular morbidity and mortality seen in this group of patients may be due to the decreased serum concentration of HD lipoprotein or an abnormal biochemical composition of the lipoproteins.We report here the analysis of serum...References1. LINDNERCHARRASHERRARDSCRIBNER ABDB. Accelerated atherosclerosis in prolonged maintenance hemodialysis. N Engl J Med. 1974;290:697-701. CrossrefMedlineGoogle Scholar2. BRUNZELLALBERSHAASGOLDBERGAGADOASHERRARD JJLALD. Prevalence of serum lipid abnormalities in chronic hemodialysis. Metabolism. 1977;26:903-10. CrossrefMedlineGoogle Scholar3. BAGDADEALBERS JJ. Plasma high-density lipoprotein concentrations in chronic-hemodialysis and renal-transplant patients. N Engl J Med. 1977;296:1436-9. CrossrefMedlineGoogle Scholar4. RAPOPORTAVIRAMCHAIMOVITZBROOK JMCJ. Defective highdensity lipoprotein composition in patients on chronic hemodialysis. N Engl J Med. 1978;299:1326-9. CrossrefMedlineGoogle Scholar5. PAPADOPOULOSKINTZIOS NJ. Determination of human serum lipoprotein patterns by agarose gel electrophoresis. Anal Biochem. 1969;30:421-6. CrossrefMedlineGoogle Scholar6. PAPADOPOULOS N. Abnormal lipoprotein patterns in human serum as determined by agarose gel electrophoresis. Clin Chem. 1979;25:1885-7. CrossrefMedlineGoogle Scholar7. PAPADOPOULOSBEDYNEK NJ. Serum lipoprotein patterns in patients with coronary atherosclerosis. Clin Chim Acta. 1973;44:153-7. CrossrefMedlineGoogle Scholar8. DAHLï¿½NERICSONFURBERG GCC. Electrophoresis of lipoproteins on cellulose acetate membrane. Acta Med Scand (Suppl). 1972;531:5-9. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byLipoprotein (a) in Chronic Renal Failure: Effect of Maintenance HemodialysisLipoprotein(a) in renal diseasePlasma lipid profile and coronary artery disease in Brazilian hemodialysis patientsLipoprotein abnormalities in hypertriglyceridaemic patients on long-term haemodialysisMust we Treat Uremic Dyslipidemia?Lipid Abnormalities in Chronic Uremic PatientsNiceritrol Reduces Plasma Lipoprotein(a) Levels in Patients Undergoing Maintenance HemodialysisThe Uremic Dyslipidemia: A Cross-Sectional and Longitudinal StudyLipoprotein(a) levels in chronic renal disease states, dialysis and transplantationIs Atherogenesis Accelerated in Hemodialysis PatientsRoles of hypoalbuminemia and lipoprotein lipase on hyperlipoproteinemia in continuous ambulatory peritoneal dialysisLipid abnormalities in renal diseaseThe Role of Cholesterol and Lipids in the Atherogenicity of Continuous Ambulatory Peritoneal Dialysis Patients Update 1990Decreased VLDL apoprotein CII/apoprotein CIII ratio may be seen in both normotriglyceridemic and hypertriglyceridemic patients on chronic hemodialysis treatmentPathogenic roles of post-heparin lipases in lipid abnormalities in hemodialysis patientsPutative atherogenic factors in patients with chronic renal failureAn Abnormal Pre-Beta Lipoprotein in Patients with Systemic MastocytosisMARIANNE FRIERI, Ph.D., M.D., NICHOLAS M. PAPADOPOULOS, Ph.D., MICHAEL A. KALINER, M.D., DEAN D. METCALFE, M.D.REFERENCES 1 May 1980Volume 92, Issue 5Page: 634-635KeywordsAtherosclerosisAttentionCoronary heart diseaseLipoproteinsMorbidityMortalityRenal failureSerum triglycerides Issue Published: 1 May 1980 PDF downloadLoading ...