tbuckley/cabot-search huggingface dataset:
Psittacosis masquerading as rheumatic fever.
Authors: R W Simpson, C Huang, D G Grahame-Smith
Journal: BMJ (1978)

stances, when the alcoholic is also depressed and has suicidal ten- dencies, it would seem wise to avoid the drug altogether.I should like to thank HM Coroner for Bedfordshire for permission to publish details of these cases; the scientific officers at the Home Office Forensic Science Laboratory, Aldermaston, Reading, who performed the analyses; and Dr J C Valentine, consultant pathologist
Anatomical lung shunting in pulmonary fibrosis.
Authors: W C Miller, J G Heard, K M Unger, D M Suich
Journal: Thorax (1986)

Eleven patients with cryptogenic fibrosing alveolitis were evaluated for the presence of pulmonary shunting by injection of radiolabelled particles of macroaggregated albumin larger than 10 micron in diameter and by body scanning with a gamma camera. The mean shunt of 9% (SD 2%) in the patients was not significantly different from the mean shunt of 7% (2%) measured in 10 normal controls. These findings suggest that shunting is not an important part of the gas exchange abnormalities noted in such patients.
TCT-214 Five-year prognostic impact of distal embolization during primary percutaneous coronary intervention in ST elevation myocardial infarction patients treated with or without distal protection
Authors: Jacob T. Lønborg, Henning Kelbaek, Steffen Helqvist, Lene Holmvang, Erik Jorgensen, Lene Kløvgaard, Kari Saunamäki, Klaus F. Kofoed, Leif Thuesen, Anne Kaltoft, Christian J. Terkelsen, Hans Erik Boetker, Jens F. Lassen, Lars Køber, Peter Clemmensen, Thomas Engstrøm
Journal: Journal of the American College of Cardiology (2013)
CHOLECYSTOCOLOSTOMY WITH A TUBE AND THE POSSIBILITY OF A VALVE FORMATION
Authors: Walter D. Wise
Journal: JAMA (1924)

In the case of Miss C. O'H., admitted to Mercy Hospital, Sept. 14, 1923, suffering with a carcinoma of the head of the pancreas (confirmed by microscopic section) and complete obstruction of the common duct, a cholecystenterostomy was not done at the primary operation, September 21, because of the fear of hemorrhage, the patient being very deeply jaundiced. This fear was substantiated by three days of postoperative bleeding from the abdominal incision, in spite of careful suturing and tying, coagulants, etc. After the jaundice disappeared, it was decided to do a cholecystenterostomy to obviate the necessity of frequent dressings and in the hope that the patient might leave the hospital. November 20, the gallbladder, on being exposed, was found to be shrunken down to dimensions of about 7 cm. in length and 2 cm. in diameter, and partially buried in the liver. It was so easily torn as to make
What's Behind Those Block Grants in Health?
Authors: Gilbert S. Omenn, Richard P. Nathan
Journal: New England Journal of Medicine (1982)

The Reagan administration's budget proposals for the 1983 fiscal year include further cuts in Medicare, Medicaid, and many other health programs. Probably the best preparation for the forthcoming debates is a review of what happened in Congress last year and of the changes that physicians and other health professionals and their patients must cope with in the current fiscal year.While public attention was riveted last year to the Reagan administration's sweeping budget and tax changes, health programs provided the battleground for an old-fashioned political showdown between the President and Congress. At stake were dozens of specific but overlapping health . . .
SEX DIFFERENCES IN HIGH-RISK ACUTE CORONARY SYNDROMES: INSIGHTS FROM EARLY-ACS
Authors: Jean-François Tanguay, L Kristin Newby, Judith Hochman, Cynthia M. Westerhout, Robert M. Califf, C Michael Gibson, Robert P. Giugliano, Robert A. Harrington, Frans Van de Werf, Paul W. Armstrong
Journal: Journal of the American College of Cardiology (2010)
THE TREATMENT OF GENITAL TUBERCULOSIS IN THE MALE
Authors: WILLIAM C. QUINBY
Journal: JAMA (1918)

For the intelligent and therefore successful treatment of any surgical ailment an exact knowledge of its pathology and mode of invading the various structures of the body is most important. In the case of tuberculosis of the male genitalia such exact knowledge is in some respects lacking; especially in regard to the structures primarily attacked by this disease. At the present writing, the majority opinion holds that the first structure to become involved in the tuberculous process is the epididymis, and that from this the disease quickly spreads to involve the vesicle and prostate. A smaller number of investigators feel that the disease begins its genital invasion in the prostate, spreading from there to the vesicles and epididymis. This is a question which has long been argued, and is of much more than mere academic importance, because only by eradicating the primary focus may we expect the greatest number of
Haemostatic variables associated with diabetes and its complications.
Authors: J H Fuller, H Keen, R J Jarrett, T Omer, T W Meade, R Chakrabarti, W R North, Y Stirling
Journal: BMJ (1979)

To study the possible role of an "increased thrombotic tendency" in the vascular complications of diabetes several tests of haemostatic function were carried out on 91 men and 63 women with diabetes aged 35-54 years and the results compared with findings in 686 men and 393 women of the same age in the Northwick Park Heart Study. Mean values for factors VII and X, fibrinogen, and platelet adhesiveness were higher in the diabetics, but mean fibrinolytic activity and whole blood platelet counts were lower. Antithrombin III values were also higher in the diabetics, which may have constituted a protective response to other changes favouring the onset of vascular disease. Diabetics with retinopathy had higher factor VII and antithrombin III values, and those with proteinuria had higher values for factor VII, fibrinogen, and platelet adhesiveness than those without these complications. These findings suggest a potentially important association between a thrombogenic tendency and vascular disease in diabetes. Nevertheless, prospective data are needed to clarify whether the haemostatic abnormalities precede the onset of clinically manifest vascular complications or are a consequence of them.
Genetic Services for Familial Cancer Patients: A Survey of National Cancer Institute Cancer Centers
Authors: Julie A. Thompson, Thomas A. Sellers, Celine Vachon, Mary Ahrens, Mary Sumpmann, John Kersey, Georgia L. Wiesner, John D. Potter
Journal: JNCI Journal of the National Cancer Institute (1995)

In the past d3ecade, significant progress has been made in understanding the genetic component of familial cancers.Genes associated with familial colon and breast cancers have recently been isolated and molecular diagnostic tests are expected to become available in the near future. Clinicians now have the opportunity to recognize and counsel individuals with elevated risk of cancer by identifying risk factors and genes associated with cancer predisposition. The rapid advances in molecular technology are a direct challenge to the medical community and cancer centers to supply specialized clinical services for familial cancers. We sought to ascertain the activities of cancer centers in the development of programs and the provision of genetic services for familial cancer. We surveyed 41 centers with National Cancer Institute (NCI) cancer center support grants. One half of the centers responding (17 of 34) reported that they provide some genetic services for familial cancer. About one half of these 17 centers (eight [57%] of 14; the three remaining clinics that responded had incomplete information on this indicator) see a variety of patient types on a small scale (fewer than 100 patients per year), and most provide four basic clinical evaluations: medical evaluation, cancer risk assessment, genetic counseling, and pedigree analysis. Staffing of each center varied widely, as did the types of screening services offered (including molecular diagnostic testing). Several centers (six [35%] of 17) indicated that they were in the developmental stages for serving familial cancer patients, and many seem to be increasing their activities in this area. The remaining 17 NCI-supported centers that responded, however, currently provide no genetic services for familial cancers. The results of this survey suggest that there is interest in developing clinical programs for familial cancers by NCI-supported cancer centers, but most of these programs are in developmental stages. A base line has been established to monitor future progress for the provision of cancer genetic services. [J Natl Cancer Inst 1995; 87:1446–55]
CHILDBIRTH AND TUBERCULOSIS
Authors: EDWARD S. McSWEENY
Journal: JAMA (1918)

It is thought that this series of childbirths in tuberculous women may be of interest because the patients were cared for in the Sea View Hospital, which makes special provision for these cases. Some time ago a ward in this hospital was designated for the care of pregnancy and childbirth in tuberculous women. There seemed to be a need for this, and apparently there were few tuberculosis institutions that attempted to fill the need. The idea, in general, was to place the pregnant tuberculous woman in this ward, where the usual sanatorium treatment for tuberculosis was carried out as much as was possible during pregnancy and after labor. <h3>ROUTINE</h3> After admission to the hospital, the taking of the history, the physical examination and the obtaining of specimens of urine, sputum, etc., were done in the general female admission wards, where the patient was placed in bed for an observation period
Plans to update European working time legislation in disarray
Authors: R. Watson
Journal: BMJ (2008)

The possibility of Britain opting out of European Union rules on weekly working hours and the status of doctors’ on-call hours hangs in the balance after the European Parliament, on 17 December, decisively rejected a proposal to update the existing legislation.

The decision effectively undermined the stance EU governments took earlier this year when they agreed that the opt out could stay indefinitely. They had also endorsed the new concept of inactive on-call time, whereby the hours doctors, nurses, and other emergency staff spend on standby at their place of work do not count towards …
Interpretation of Serum Creatine Phosphokinase
Authors: Victor M. Rivera
Journal: JAMA (1973)

<h3>To the Editor.—</h3> The article by Nevins et al (224:1382, 1973) on pitfalls in interpreting serum creatine phosphokinase activity (CPK) and reviewed causes of CPK elevation other than myocardial injury deserves comment. I would like to report a patient with marked elevations of serum creatine phosphokinase levels while he had reversible myopathy and hypokalemia, presumably due to chronic administration of fludrocortisone (Florinef) acetate for severe postural hypotension. This patient's primary diagnosis was "central neurogenic orthostatic hypotension" (Shy-Drager syndrome) and the neurological problem has been reported elsewhere.<sup>1</sup> <h3>Report of a Case.—</h3> A 63-year-old salesman complained of blurred vision, impotence, and syncope for 20 years. At age 61, he was incapacitated by orthostatic ataxia, hypotension, and tremor and was forced to retire. At age 62, the hypotensive attacks had increased in frequency and severity, and he spent most of his time lying down. The blood pressure ranged from 70/50 to 120/90
Cardiac Resynchronization and Death From Progressive Heart Failure
Authors: David J. Bradley, Elizabeth A. Bradley, Kenneth L. Baughman, Ronald D. Berger, Hugh Calkins, Steven N. Goodman, David A. Kass, Neil R. Powe
Journal: JAMA (2003)

<h3>Context</h3> Progressive heart failure is the most common mechanism of death among patients with advanced heart failure. Cardiac resynchronization, a pacemaker-based therapy for heart failure, enhances cardiac performance and quality of life, but its effect on mortality is uncertain. <h3>Objective</h3> To determine whether cardiac resynchronization reduces mortality from progressive heart failure. <h3>Data Sources</h3> MEDLINE (1966-2002), EMBASE (1980-2002), the Cochrane Controlled Trials Register (Second Quarter, 2002), The National Institutes of Health ClinicalTrials.gov database, the US Food and Drug Administration Web site, and reports presented at scientific meetings (1994-2002). Search terms included<i>pacemaker</i>,<i>pacing</i>,<i>heart failure</i>,<i>dual-site, multisite</i>,<i>biventricular</i>,<i>resynchronization</i>, and<i>left ventricular preexcitation</i>. <h3>Study Selection</h3> Eligible studies were randomized controlled trials of cardiac resynchronization for the treatment of chronic symptomatic left ventricular dysfunction. Eligible studies reported death, hospitalization for heart failure, or ventricular arrhythmia as outcomes. Of the 6883 potentially relevant reports initially identified, 11 reports of 4 randomized trials with 1634 total patients were included in the meta-analysis. <h3>Data Extraction</h3> Trial reports were reviewed independently by 2 investigators in an unblinded standardized manner. <h3>Data Synthesis</h3> Follow-up in the included trials ranged from 3 to 6 months. Pooled data from the 4 selected studies showed that cardiac resynchronization reduced death from progressive heart failure by 51% relative to controls (odds ratio [OR], 0.49; 95% confidence interval [CI], 0.25-0.93). Progressive heart failure mortality was 1.7% for cardiac resynchronization patients and 3.5% for controls. Cardiac resynchronization also reduced heart failure hospitalization by 29% (OR, 0.71; 95% CI, 0.53-0.96) and showed a trend toward reducing all-cause mortality (OR, 0.77; 95% CI, 0.51-1.18). Cardiac resynchronization was not associated with a statistically significant effect on non–heart failure mortality (OR, 1.15; 95% CI, 0.65-2.02). Among patients with implantable cardioverter defibrillators, cardiac resynchronization had no clear impact on ventricular tachycardia or ventricular fibrillation (OR, 0.92; 95% CI, 0.67-1.27). <h3>Conclusions</h3> Cardiac resynchronization reduces mortality from progressive heart failure in patients with symptomatic left ventricular dysfunction. This finding suggests that cardiac resynchronization may have a substantial impact on the most common mechanism of death among patients with advanced heart failure. Cardiac resynchronization also reduces heart failure hospitalization and shows a trend toward reducing all-cause mortality.
SARS — One Year Later
Authors: Donald E. Low, Allison McGeer
Journal: New England Journal of Medicine (2003)

It was just over a year ago, in November 2002, that the first case of what was to become known as the severe acute respiratory syndrome (SARS) was identified in Foshan, Guangdong Province, China. The dramatic spread of SARS in the late winter and spring of 2003 appeared at first to herald the onset of a new infectious disease that would become endemic worldwide. However, almost as quickly as it spread, it was brought under control. As evidenced in this issue of the Journal in a report by Olsen et al. (pages 2416–2422) and a review article by Peiris et . . .
Feeling and Space
Authors: Richard Donze
Journal: Annals of Internal Medicine (2010)

Ad Libitum16 February 2010Feeling and SpaceRichard Donze, DO, MPHRichard Donze, DO, MPHFrom West Chester, PA 19380-6706.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-152-4-201002160-00013 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail A scanned copyof a fax of ahandwritten letterof complaint hadclear enoughcursive sweep tosee the awkwardstretch for a nounabout feeling andthe spelling slip toan adjective aboutspace—”He hadno empty formy pain.”A font-9 orderfrom a pick-listclick stoppingpoppy products byvein mouth or skinwas unclear aboutfeeling but theauto time stampat 2031 hintedspace had shrunkand scrubbed asoapy A list fromfive to one—“drug-seeking.”No feisty jumpto conclusionsbut weary slideto E on bothfeeling and spaceand timeto sign out.Richard Donze, DO, MPHWest Chester, PA 19380-6706 Author, Article, and Disclosure InformationAffiliations: From West Chester, PA 19380-6706.Current Author Address: Richard Donze, DO, MPH, 241 Cheshire Circle, West Chester, PA 19380-6706. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 16 February 2010Volume 152, Issue 4Page: 262KeywordsDrugsEmotionsMouthVeins ePublished: 16 February 2010 Issue Published: 16 February 2010 Copyright & PermissionsCopyright © 2010 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Objects to the Term "Jackass."
Authors: Louis Edelman
Journal: JAMA (1893)

Detroit, Mich., Oct. 25, 1893. <h3>To the Editor:</h3> —The scientific language used in the argument by Dr. Solomon Solis-Cohen against Dr. John B. Roberts and his article, "The Similarity between Physicians and Homeopaths," is worthy of remark. His article is illiberal, un-American, and based upon an unscientific principle of thought. A principle of science that has been accepted by all civilization is true; but a principle of science which has not reached its perfection and its acceptance by the whole civilized world is not true, as yet. The paper, as a whole, was more suitable for a political gathering than a scientific society. No matter what ideas a man may have, he is never to be compared to a mule or a jackass. It is ungentlemanly to speak thus of a class of excellent men who are entitled to the respect of those who can not agree with them.
A survey on the effect of aerobic exercises on function and structure of heart in diabetic male rats of Sprague Dawley-Albino species
Authors: Ali Khajehlandi, Amin Mohannadi Domieh
Journal: British Journal of Sports Medicine (2010)

The aim of this research was to study the effect of aerobic physical exercises on the performance and heart structure of diabetic mice. Thus, 48 male mice from Sprague Dawley race with the weight of 150–300 g were bought and divided randomly in four groups, each including 12 mice. These four groups consisted of the control group with physical exercise, the control group without physical exercise, diabetic group without physical exercise and diabetic group with physical exercise. These mice were affected by diabetes by the injection of streptozotocin. The exercise protocol included three procedures: the first 4 weeks with the speed of 12 m in a minute during the time of 10 min, the second 4 weeks with the speed of 22–23 m in a minute during the time of 40 min and the final 4 weeks with the speed of 23–25 m on a minute during the time of 1 h. In this research, the levels of blood sugar and the lipoproteins were measured by enzyme method and the blood pressure, thickness and cavity of heart by sensitive electrodes and echocardiography. The results showed that after 4 weeks of physical exercise, the levels of sugar, blood pressure and lipoproteins had not changed anyway but after 12 weeks of physical exercise, it was determined that the levels of blood sugar and blood pressure in diabetic group with physical exercise have decreased meaningfully (p&lt;0.05). In addition, this low blood sugar and low blood pressure had a positive and meaningful relation with each other. Also the thickness and cavity of the ventricle in the diabetic group with physical exercise had increased but the changes in blood sugar had just meaningful relation with the changes in the thickness of the ventricle (p&lt;0.05).
Perception, learning, and judgment in ecological psychology: Who needs a constructivist ventral system?
Authors: Clinton Cooper, Claire F. Michaels
Journal: Behavioral and Brain Sciences (2002)

Norman's identification of a ventral system embodying a constructivist theory of perception is rejected in favor of an ecological theory of perception and perceptual learning. We summarize research showing that a key motivation for the ventral-constructivist connection, percept-percept coupling, confuses perceptual and post-perceptual processes
CONTINUED SUBNORMAL TEMPERATURE IN INFANCY
Authors: HENRY W. CHENEY
Journal: JAMA (1910)

The opportunity to observe and study a case of continued subnormal temperature in an infant, recently, has interested me in the subject. On looking up the literature, however, one finds much written about fever and increase of temperature, but very little recorded or written on subnormal temperature. The text-books, also, usually dismiss the subject with a few lines or, perhaps, in the description of a disease, merely say that the temperature may be below normal. Have we not, as physicians, been too prone to disregard those depressions of temperature below normal and to consider only the occurrence of fever as of clinical significance? We do this perhaps from indifference or because there seems no ready explanation of the hypothermia. Cases of noticeably low temperature in adults appear to be recorded more often than do those of infants or children. Then too, the cases observed have been usually of some fatal
INVERSE RELATIONSHIP BETWEEN HDL-C RAISING AND HSCRP REDUCTION IN OLDER PATIENTS TREATED WITH LIPID-LOWERING THERAPY
Authors: William V. Brown, JoAnne M. Foody, Franklin Zieve, Charlotte Jones-Burton, Qian Dong, Joanne E. Tomassini, Arvind Shah, Andrew M. Tershakovec
Journal: Journal of the American College of Cardiology (2010)
H19, a marker of developmental transition, is reexpressed in human atherosclerotic plaques and is regulated by the insulin family of growth factors in cultured rabbit smooth muscle cells.
Authors: D K Han, Z Z Khaing, R A Pollock, C C Haudenschild, G Liau
Journal: Journal of Clinical Investigation (1996)

H19 is a developmentally regulated gene with putative tumor suppressor activity, and loss of H19 expression may be involved in Wilms' tumorigenesis. In this report, we have performed in situ hybridization analysis of H19 expression during normal rabbit development and in human atherosclerotic plaques. We have also used cultured smooth muscle cells to identify H19 regulatory factors. Our data indicate that H19 expression in the developing skeletal and smooth muscles correlated with specific differentiation events in these tissues. Expression of H19 in the skeletal muscle correlated with nonproliferative, actin-positive muscle cells. In the prenatal blood vessel, H19 expression was both temporally and spatially regulated with initial loss of expression in the inner smooth muscle layers adjacent to the lumen. We also identified H19-positive cells within the adult atherosclerotic lesion and we suggest that these cells may recapitulate earlier developmental events. These results, along with the identification of the insulin family of growth factors as potent regulatory molecules for H19 expression, provide additional clues toward understanding the physiological regulation and function of H19.
A Method of Securing the Direct Body Ballistocardiogram by Means of a Microscope, Giving a Record Readily Calibrated
Authors: E. W. BIXBY, C. B. HENDERSON
Journal: Circulation (1953)

We describe a simple method of recording the direct body ballistocardiogram by means of a microscope and a powerful light source. The beam passes through a slit attached to the body, and the image of this moving slit is magnified by the microscope and focused on moving photographic paper. When a static force is applied to the body, the base line of the record is permanently displaced and so the amplitude of the ballistocardiogram can be calibrated. By superimposing a ballistocardiogram obtained by means of the electrocardiogram on the same film, accurate comparisons of the two records and a calibration of the electrical instrument can be obtained.