CHLOROQUINE PHOSPHATE (ARALEN) IN THE LONG-TERM TREATMENT OF RHEUMATOID ARTHRITIS
Authors: J. PAUL YOUNG
Journal: Annals of Internal Medicine (1959)

Article1 December 1959CHLOROQUINE PHOSPHATE (ARALEN) IN THE LONG-TERM TREATMENT OF RHEUMATOID ARTHRITISJ. PAUL YOUNG, M.D.J. PAUL YOUNG, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-51-6-1159 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThis report describes the results obtained in a group of 50 consecutive private patients with chronic rheumatoid arthritis who received chloroquine phosphate (Aralen) as the major medical agent in the management of their disease for 18 to 36 months. The average duration of treatment was 24 months. An analysis of the successes and failures in this group will be presented with the clinical, laboratory and radiological changes that occurred during treatment. A dose schedule was evolved which was found to give the best results to the greatest number of patients with the least incidence of side effects.During an intensive...Bibliography1. 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Author, Article, and Disclosure InformationAffiliations: Asheville, North Carolina*Received for publication July 6, 1959.Requests for reprints should be addressed to J. Paul Young, M.D., 180 Biltmore Avenue, Asheville, N. C. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByAntimalarials in rheumatic diseasesSlow-acting antirheumatoid drugsAntimalarial drugs for rheumatoid arthritisUse of synthetic antimalarial drugs and other agents for rheumatoid arthritis: Historic and therapeutic perspectivesDrug therapy (3): 'specific' drugsChloroquine and Hydroxychloroquine in Rheumatological TherapyRecent developments in disease-modifying antirheumatic drugsChloroquine Retinopathy in Patients with Rheumatoid ArthritisThe effect of sodium aurothiomalate ("Myocrisin") on multivesicular body formation in cultured sheep lymphocytesAn appraisal of chloroquineRheumatism and Arthritis Review of American and English Literature of Recent Years (Fourteenth Rheumatism Review)CHARLEY J. SMYTH, M.D., F.A.C.P., ROGER L. BLACK, M.D., CHARLES L. CHRISTIAN, M.D., EPHRAIM P. ENGLEMAN, M.D., F.A.C.P., EDWARD C. FRANKLIN, M.D., DONALD F. HILL, M.D., F.A.C.P., JOSEPH L. HOLLANDER, M.D., F.A.C.P., HOWARD L. HOLLEY, M.D., F.A.C.P., JOHN G. MAYNE, M.D., WILLIAM M. MIKKELSEN, M.D., CHARLES L. SHORT, M.D., F.A.C.P., HUGH A. SMYTHE, M.D., F.R.C.P.(C), OTTO STEINBROCKER, M.D., HOWARD J. WEINBERGER, M.D.Retinopathy associated with chloroquine phosphate therapy 1 December 1959Volume 51, Issue 6Page: 1159-1178KeywordsArthritisChloroquineClinical laboratoriesPhosphatesRheumatoid arthritisSteroid therapy Issue Published: 1 December 1959 PDF DownloadLoading ...