Hepatitis C in Hospital Employees with Needlestick Injuries
Authors: Kendo Kiyosawa, Takeshi Sodeyama, Eiji Tanaka, Yoshiyuki Nakano, Seiichi Furuta, Kusuya Nishioka, Robert H. Purcell, Harvey J. Alter
Journal: Annals of Internal Medicine (1991)

Brief Reports1 September 1991Hepatitis C in Hospital Employees with Needlestick InjuriesKendo Kiyosawa, MD, Takeshi Sodeyama, MD, Eiji Tanaka, MD, Yoshiyuki Nakano, MD, Seiichi Furuta, MD, Kusuya Nishioka, MD, Robert H. Purcell, MD, Harvey J. Alter, MDKendo Kiyosawa, MDSearch for more papers by this author, Takeshi Sodeyama, MDSearch for more papers by this author, Eiji Tanaka, MDSearch for more papers by this author, Yoshiyuki Nakano, MDSearch for more papers by this author, Seiichi Furuta, MDSearch for more papers by this author, Kusuya Nishioka, MDSearch for more papers by this author, Robert H. Purcell, MDSearch for more papers by this author, Harvey J. Alter, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-115-5-367 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptHepatitis virus infection has been a problem among hospital employees. Hepatitis B virus (HBV) infection is now controlled by hospital safety practices limiting exposure to blood and other body fluids and by both passive and active immunization (1). Without an antigen-antibody system for detecting non-A, non-B hepatitis virus, there has been no way to confirm this diagnosis or to establish that the hepatitis developing in a needlestick recipient was related to that of the implicated patient. Recently, the primary agent of non-A, non-B hepatitis, now designated hepatitis C virus (HCV), has been cloned (2), and an assay to detect antibody...References1. SeeffHoofnagle LJ. Immunoprophylaxis of viral hepatitis. Gastroenterology. 1979;77:161-82. CrossrefMedlineGoogle Scholar2. ChooKuoWeinerOverbyBradleyHoughton QGALDM. Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science. 1989;244:359-62. CrossrefMedlineGoogle Scholar3. KuoChooAlterGitnickRedekerPurcell GQHGAR. 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ShikataKarasawaAbeUzawaSuzukiOda TTKTHT. Hepatitis B e antigen and infectivity of hepatitis B virus. J Infect Dis. 1977;136:571-6. CrossrefMedlineGoogle Scholar8. PonzettoHoyerPopperEnglePurcellGerin ABHRRJ. Titration of the infectivity of hepatitis D virus in chimpanzees. J Infect Dis. 1987;155:122-8. CrossrefGoogle Scholar9. EverhartDi BisceglieMurrayAlterMelpolderKuo JALHJG. Risk for non-A, non-B (type C) hepatitis through sexual or household contact with chronic carriers. Ann Intern Med. 1990;112:544-5. LinkGoogle Scholar10. GiovanniniTaggerRiberoZuccottiPoglianiGrossi MAMGLA. Maternal-infant transmission hepatitis C virus and HIV infections: a possible interaction [Letter]. Lancet. 1990;335:1166. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: From the Shinshu University School of Medicine, Matsumoto, Japan; the Japanese Red Cross Central Blood Center, Tokyo, Japan; and the National Institute of Allergy and Infectious Disease and the Warren Grant Magnuson Clinical Center, the National Institutes of Health, Bethesda, Maryland. For current author addresses, see end of text. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byMathematical Modeling of Chronic Hepatitis C Treatment’s Effect on the Evolution of its ComplicationsEpidemiology and management of hepatitis C virus infections in immigrant populationsTHE PREVALENCE RATE OF HEPATITIS C VIRUS IN BASRAH CITY AND THE COMMON CAUSATIVE RISK FACTORSHCV Exposure in the Health Care Arena. 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