tbuckley/cabot-search huggingface dataset:
Prognostic value of inducible myocardial ischemia in predicting cardiovascular events after renal transplantation
Authors: Bertrand Dussol, Jean-Louis Bonnet, Jerome Sampol, Bernard Savin, Catherine De La Forte, Olivier Mundler, Gilbert Habib, Sophie Morange, Karine Barrau, Anderson Loundoun, Henri Vacher-Coponat, Yvon Berland
Journal: Kidney International (2004)
Elevators on His Mind
Authors: Peter S. Stack
Journal: Annals of Internal Medicine (2004)

On Being a Patient17 August 2004Elevators on His MindPeter S. Stack, MDPeter S. Stack, MDFrom Dallas Diagnostic Association, Dallas, TX 75230.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-141-4-200408170-00014 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail “Alex rides elevators on his mind” was written by my 10-year-old autistic son and taped to the wall next to his bed. Elevators are the central focus of Alex's attention at this point in his life. His form of autism is described as high-functioning, since his intelligence measures in the normal range. However, he has many typical features of autism, the most dramatic being an obsessive interest in narrowly defined topics. This bizarre and mystifying behavior is a daily reminder of his brain's remarkable capabilities and its frustrating limitations, reinforcing the notion of some critical derangement in the scaffolding that ... Author, Article, and Disclosure InformationAuthors: Peter S. Stack, MDAffiliations: From Dallas Diagnostic Association, Dallas, TX 75230.Corresponding Author: Peter S. Stack, MD, Dallas Diagnostic Association, 7777 Forest Lane, Suite C-300, Dallas, TX 75230; e-mail, ps.stack@bhcs.com. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 17 August 2004Volume 141, Issue 4Page: 319-320KeywordsAutismBehaviorChildrenEmotionsEngineersForecastingIntelligenceMemoryMotivationTicks ePublished: 17 August 2004 Issue Published: 17 August 2004 Copyright & PermissionsCopyright © 2004 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
The lingering dilemma of arterial pressure in CKD: what do we know, where do we go?
Authors: Rajiv Agarwal, Alberto Martinez-Castelao, Andrzej Wiecek, Ziad Massy, Gultekin Suleymanlar, Alberto Ortiz, Peter J. Blankestijn, Adrian Covic, Friedo W. Dekker, Kitty J. Jager, Bengt Lindholm, David Goldsmith, Danilo Fliser, Gerard London, Carmine Zoccali
Journal: Kidney International Supplements (2011)
Repeated infusions of infliximab, a chimeric anti-TNFalpha monoclonal antibody, in patients with active spondyloarthropathy: one year follow up
Authors: E Kruithof
Journal: Annals of the Rheumatic Diseases (2002)

Background: In a pilot study, the anti-tumour necrosis factor α monoclonal antibody, infliximab, induced a rapid and significant improvement in global, peripheral, and axial disease manifestations of patients with active spondyloarthropathy. Objective: To determine whether repeated infusions of infliximab would effectively and safely maintain the observed effect. Methods: Safety and efficacy of a maintenance regimen (5 mg/kg infliximab every 14 weeks) was evaluated using the measurements reported in the pilot study. Of the 21 patients, 19 completed the one year follow up for efficacy; two patients changed to another dosing regimen after week 12 owing to partial lack of efficacy. However, they are still being followed up for safety analysis. Results: After each re-treatment a sustained significant decrease of all disease manifestations was observed. Before re-treatment, symptoms recurred in 3/19 (16%) at week 20, in 13/19 (68%) at week 34, and in 15/19 (79%) at week 48. No withdrawals due to adverse events occurred. Twelve minor infectious episodes were observed. Twelve patients (57%) developed antinuclear antibodies; in four of them (19%) anti-dsDNA antibodies were detected. However, no lupus-like symptoms occurred. Conclusion: In this open study of infliximab in patients with active spondyloarthropathy, the significant improvement of all disease manifestations was maintained over a one year follow up period without major adverse events. Although recurrence of symptoms was noted in a rising number of patients before each re-treatment, no loss of efficacy was observed after re-treatment.
1025-98 Exaggerated Sympathetic and Failed Withdrawal of Parasympathetic Activity During Head-up Tilt Precipitates a Life-threatening Cardiac Asystole
Authors: Bonpei Takase, Akira Kurita, Tomoo Nagai, Sinji Nakao, Ritusi Kato, Hideki Mitani, Koh Arakawa, Haruo Nakamura
Journal: Journal of the American College of Cardiology (1995)
Letter: Danger of saline emetics in first-aid for poisoning.
Authors: C A Bird, A W Gardner, P J Roylance
Journal: BMJ (1974)

different (t = 163, P = 0 20) and breast and bottle feeding were equally distributed between the two groups x2 = 0 054; N.S.).Though the mean duration of infusion of oxytocin in group 1 (10-8 ± 8-7 hr) was greater than in group 2 (8 0 ± 7-1 hr) the difference was not statistically significant (t = 1 49, P = 0-14).We agree with Dr. B. Alderman and Professor J. M. Beazley (7 September, p. 624) that the first and sixth days are not ideal times to detect peak neonatal bilirubin levels.However, as we pointed out in our paper, the sixth day was a time at which blood was already being taken routinely for amino-acid screening and this timing of samples avoided exposing the infants to additional blood-letting.Though the re- corded peak values in our data may be lower for this reason, any increase in neonatal hyperbilirubinaemia should still be reflected in a higher mean value on the sixth day.-We are, etc.,
1002 Comparison of once-daily triamcinolone acetonide aqueous nasal spray and twice-daily beconase AQ® for the treatment of seasonal allergic rhinitis due to ragweed
Authors: C LAFORCE, F HAMPEL, F KIECHEL, W LUMRY, J MURRAY, J FURST, B SIMPSON, J SMITH
Journal: Journal of Allergy and Clinical Immunology (1996)
Hypertrophic Obstructive Subvalvular Mitral Stenosis.
Authors: Ralph Shabetai
Journal: Annals of Internal Medicine (1970)

Meeting Abstracts1 May 1970Hypertrophic Obstructive Subvalvular Mitral Stenosis.Ralph Shabetai, M.D., F.A.C.P., Sidney Davidson, M.D.Ralph Shabetai, M.D., F.A.C.P.Search for more papers by this author, Sidney Davidson, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-72-5-783_3 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIt is now appreciated that primary myocardial disease is common, frequently causes symptoms, and produces heart failure. Of the hypertrophic types, obstructive cardiomyopathy affecting the outflow tract of the left ventricle is the best known. The possibility that hypertrophic cardiomyopathy may obstruct inflow into the left ventricle and simulate mitral stenosis has been suggested by some authorities on primary myocardial disease, but no case is documented in the literature. Three cases were described in this paper.All three were women with symptoms of pulmonary congestion referred for mitral valvotomy. In all a loud first heart sound, a rumbling apical diastolic... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Lexington, Ky. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDifferential diagnosis of cardiomyopathies 1 May 1970Volume 72, Issue 5Page: 783-784KeywordsCardiomyopathiesHeartHeart diseasesHeart failureLeft ventricleMitral stenosis Issue Published: 1 May 1970 PDF downloadLoading ...
Immune Thrombocytopenia Following α-Interferon Therapy in Patients With Cancer
Authors: Peter McLaughlin, Moshe Talpaz, Jorge R. Quesada, Abdus Saleem, Barthel Barlogie, Jordan U. Gutterman
Journal: JAMA (1985)

Immune thrombocytopenia occurred in five patients with cancer receiving alpha-interferon. The median pretreatment platelet count was 217,000/cu mm, which fell to a median of 12,000/cu mm after a median of 25 days of interferon therapy. All had normal numbers of megakaryocytes, with dysplasia noted in three; all four who were tested had platelet-associated immunoglobulin. All had normalization of platelet counts with prednisone therapy. Four tolerated re-treatment with interferon, two with concurrent prednisone administration and two others following splenectomy. Immune thrombocytopenia should be considered in patients who become thrombocytopenic during interferon therapy.
Prospective CT Screening for Lung Cancer in a High-Risk Population: HIV-Positive Smokers
Authors: Alicia Hulbert, Craig M. Hooker, Jeanne C. Keruly, Travis Brown, Karen Horton, Eliott Fishman, Kristen Rodgers, Beverly Lee, Celis Sam, Salina Tsai, Elizabeth Weihe, Genevieve Pridham, Brad Drummond, Christian Merlo, Maria Geronimo, Michelle Porter, Solange Cox, Dan Li, Marian Harline, Mario Teran, John Wrangle, Beatrice Mudge, Gregory Taylor, Gregory D. Kirk, James G. Herman, Richard D. Moore, Robert H. Brown, Malcolm V. Brock
Journal: Journal of Thoracic Oncology (2014)
"THE VALUE OF THE TOXIN OF RHUS TOXICODENDRON AND RHUS VENENATA"
Authors: Albert Strickler
Journal: JAMA (1923)

<h3>To the Editor:</h3> —InThe Journal, June 2, p. 1588, is an article by Dr. Albert Strickler on "The Value of the Toxin (Antigen) of Rhus Toxicodendron and Rhus Venenata." This material is considered in its relation to treatment during the attack and to immunization. A table of cases treated by thirty-five physicians sets forth the records of 356 patients, though nineteen of the physicians reported less than five cases each. "In the vast majority of cases, improvement was noted twenty-four hours after the institution of this mode of treatment." In the second paragraph of the "comment," bearing on desensitization, occurs the statement, "It is incapable of doing harm." With this remark I beg to differ. In the early summer of 1921, a medical student came to the Jefferson Hospital Skin Dispensary with this history: He had had an attack of dermatitis venenata and had been treated by Dr. Strickler.
HIV Infection and Risk Behaviors Among Heterosexuals in Alcohol Treatment Programs
Authors: Andrew L. Avins
Journal: JAMA (1994)

<h3>Objective.</h3> —To measure the prevalence of human immunodeficiency virus (HIV) infection and high-risk behaviors among heterosexuals in alcohol treatment. <h3>Design.</h3> —Cross-sectional survey. <h3>Setting.</h3> —Five public alcohol treatment centers. <h3>Subjects.</h3> —Consecutive sample of 888 heterosexual clients entering treatment between October 1990 and December 1991. Respondents were 51% black, 10% Hispanic, 33% white, and 76% male. The overall response rate was 68%. <h3>Measurements.</h3> —Structured interview and serotesting for HIV antibodies. <h3>Results.</h3> —The overall seroprevalence of HIV infection was 5% (95% confidence interval, 3% to 6%). There were no significant differences in rates of infection by age, gender, or race. The prevalence of infection in heterosexual respondents without a history of injection drug use was 3% in men and 4% in women, several times higher than published estimates from a similar community-based heterosexual sample. Unsafe sexual practices were common: 54% of respondents reported multiple sexual partners in the previous year, 97% of nonmonogamous respondents did not use condoms during all sexual encounters, and few respondents consistently asked new sexual partners about previous high-risk behaviors. <h3>Conclusions.</h3> —There is a substantial prevalence of HIV infection among heterosexual clients in San Francisco (Calif) alcohol treatment programs, much of which is not associated with injection drug use. Because of this and the high prevalence of unsafe sexual behaviors, there is a relatively high likelihood of heterosexual spread of HIV among the large population of clients seeking treatment for alcohol dependency. Interventions to prevent HIV spread should become a standard part of alcohol treatment programs. (<i>JAMA</i>. 1994;271:515-518)
TB epidemic is still growing in Africa and in eastern Europe
Authors: P. Moszynski
Journal: BMJ (2003)

Tremendous progress has been made in combating tuberculosis, Dr Jong Wook Lee, director general designate of the World Health Organization, said this week. Ten million people have now been successfully treated with the “directly observed treatment, short course” (DOTS) multidrug programme of treatment. But HIV infection, population growth, poverty, and migration could undermine this success.

Launching WHO's 2003 Global Tuberculosis Control report in London Dr Lee said: “For the …
Three hundred years of psychiatry 1535-1860; a history in selected English texts.
Authors: Lester S. King
Journal: JAMA (1963)

The authors contend that psychiatry, with its many different attitudes, concepts, theories, and therapies, belongs to both the natural sciences and the humanities. One suitable approach to understanding, therefore, would be through the discipline of history. The authors hope "to get the present in perspective by tracing the problems of the past and how modern views and trends develop." Trying thus to record the problems and growth of clinical psychiatry and to achieve a suitable perspective, the authors combed not only the psychiatric literature in the strict sense, but also many varied sources, including philosophy, psychology, literature, autobiographies, and other areas. Even unpublished manuscripts have been drawn upon. However, only works in English (original publications or translations) are used. The book consists of relevant excerpts, generally from one half to two or three pages in length, together with explanatory and expository comments. The arrangement is chronological, the earliest excerpt being
Unpredictable Drug Shortages: An Ethical Framework for Short-Term Rationing in Hospitals
Authors: Philip M. Rosoff
Journal: The American Journal of Bioethics (2012)

Periodic and unexpected shortages of drugs, biologics, and even medical devices have become commonplace in the United States. When shortages occur, hospitals and clinics need to decide how to ration their available stock. When such situations arise, institutions can choose from several different allocation schemes, such as first-come, first-served, a lottery, or a more rational and calculated approach. While the first two approaches sound reasonable at first glance, there are a number of problems associated with them, including the inability to make fine, individual patient-centered decisions. They also do not discriminate between what kinds of patients and what types of uses may be more deserving or reasonable than others. In this article I outline an ethically acceptable procedure for rationing drugs during a shortage in which demand outstrips supply.
Blue Ridge Orthopedics
Authors: David Couk
Journal: JAMA (1982)

<h3>A Drive Through the Country</h3> There was a period during what I now call "the bad old days" when I was the only practicing orthopedist in all of Culpeper, Fauquier, Orange, Madison, and Rappahannock counties, an area in northwestern Virginia with a population of almost 80,000.I look back and wonder how and why I kept going during those years. I remember one Mother's Day weekend when I worked night and day, except for a few short naps, all day Thursday, Friday, Saturday, and Sunday. We were having a large number of car accidents with serious injuries. I finally got to bed at around ten o'clock on Sunday night. I had a heavy operating schedule the following day, so I was thankful to get some sleep. I had slept for about two hours when the phone rang. (I always put my phone on the far side of the room, because if
Photosensitivity in lupus erythematosus, UV photoprovocation results compared with history of photosensitivity and clinical findings
Authors: T. HASAN, F. NYBERG, E. STEPHANSSON, P. PUSKA, M. HÄKKINEN, S. SARNA, A-M. ROS, A. RANKI
Journal: British Journal of Dermatology (1997)

Photosensitivity, one of the presenting symptoms in lupus erythematosus (LE), is still poorly defined and varying prevalence figures have been reported. The possibility of a coexisting photodermatosis, especially polymorphous light eruption (PLE), has often not been taken into account. We report the results of ultraviolet A (UVA) and B (UVB) photoprovocation tests in 67 clinically photosensitive patients who had confirmed discoid LE (DLE), systemic LE (SLE) or subacute cutaneous LE (SCLE). The results are compared with a detailed history of photosensitivity and with clinical and serological findings. A pathological photoprovocation reaction, graded as weak, moderate or strong, was induced with either UVA or UVB in 69% of patients with LE, in 100% of those with SCLE, in 70% of those with SLE and in 64% of those with DLE, but in none of 14 controls. Only 16% of the pathological reactions were strong and long-lasting, resembling LE lesions, while 48% were moderate or weak and transient, clinically like PLE. Fifty-three per cent of the provocation reactions which were biopsied showed a PLE-like histology or a non-specific inflammatory reaction, and most of them were clinically moderate or weak reactions of short duration. In the remaining, mostly clinically strong or long-lasting reactions, the histology was consistent with LE. A history of sunlight sensitivity did not predict a pathological photoprovocation result but a positive association between the presence of SSA/Ro or SSB/La antibodies and a pathological photoprovocation reaction was found. We have shown that PLE coexists with LE and that both PLE- and LE-like lesions can be induced with UV radiation in LE patients.
OP0207 The “Fast Track” Giant Cell Arteritis Outpatient Clinic: A Useful Tool to Reduce the Morbidity of Disease?
Authors: A. P. Diamantopoulos, G. Haugeberg, H. Hetland, D. M. Soldal, G. Myklebust
Journal: Annals of the Rheumatic Diseases (2013)

<h3>Background</h3> Permanent visual loss is one of the most serious complications in giant cell arteritis (GCA). Visual manifestations have been reported in 26% and permanent visual loss in up to 15% of the GCA patients (1). <h3>Objectives</h3> The aim of this retrospective study was to examine if the implementation of the “fast track” principle in an outpatient clinic for GCA patients could reduce the rate of transient and permanent visual loss. <h3>Methods</h3> Patients suspected to have GCA were consecutively evaluated between March 2010 and December 2012 by color Doppler ultrasound (CDUS). The “Fast- track” principle (quick evaluation by CDUS during 24 hours, and immediate initiation of treatment if appropriate) was implemented in our outpatient clinic from March 2012. All the patients fulfilled the American College of Rheumatology Classification Criteria for GCA (2) and had a positive CDUS of the temporal artery. Chi-square test was used for group comparison and p values &lt; 0.05 were considered significant. <h3>Results</h3> During the evaluation period 46 patients were diagnosed to have GCA. Among the 46 patients, 28 patients were traditionally evaluated between March 2010 and February 2012. Vision disturbances were observed in 7 patients, 6 of them suffered from permanent (21.5 %) vision loss in one (5 patients) or both eyes (1 patient). Among the 18 patients evaluated by the “fast track” principle (from March to December 2012), 2 (11.1%) had transient visual manifestations and none suffered from permanent visual loss. The difference between the two groups with regard to permanent visual loss was statistically significant (p=0.035). <h3>Conclusions</h3> Our data indicate that a “Fast-track” approach including a rapid assessment with ultrasonography may significantly reduce the permanent vision loss in GCA patients. These encouraging observations need to be confirmed in larger groups of patients. <h3>References</h3> Gonzalez-Gay MA, Garcia-Porrua C, Llorca J, Hajeer AH, Branas F, Dababneh A, et al. Visual manifestations of giant cell arteritis. Trends and clinical spectrum in 161 patients. Medicine (Baltimore). 2000;79(5):283-92. Epub 2000/10/20. Hunder GG, Bloch DA, Michel BA, Stevens MB, Arend WP, Calabrese LH, et al. The American College of Rheumatology 1990 criteria for the classification of giant cell arteritis. Arthritis Rheum. 1990;33(8):1122-8. Epub 1990/08/01. <h3>Disclosure of Interest</h3> None Declared
Letter by Vogt Regarding Article, “Reduction in the Incidence of Acute Myocardial Infarction Associated With a Citywide Smoking Ordinance”
Authors: Richard L. Vogt
Journal: Circulation (2007)

I read with interest the article by Bartecchi et al. 1 I applaud the authors for studying the relationship between the incidence of acute myocardial infarction (AMI) and the enactment of a smoke-free ordinance in one community.However, the results need to be interpreted with caution.The authors of the study employed a before-after study design that lacks scientific rigor in clearly establishing a relationship between AMIs and the smokefree ordinance.The authors' finding is notable but is somewhat diminished by the fact that there are no data on exposure to active or passive smoking presented in this study, which would have provided more convincing evidence of a true association.It was interesting to see that there were no similar reductions of AMIs in surrounding communities that did not have an ordinance change.However, there could be other, unknown reasons for the reduction of AMIs in Pueblo in the 18 months after the ordinance was instituted.In the future, it would be helpful for researchers studying similar communities to obtain both active and passive smoking exposure data to better determine the association with a change in incidence of AMIs or other cardiovascular events.Fortunately, there are multiple other, more rigorous studies that have shown a true health risk due to active and passive smoke exposure.
Should psychiatrists protect the public?
Authors: J. Coid
Journal: BMJ (2003)

As conservative members of the middle classes, most psychiatrists probably support recent criminal legislation designed to improve public protection by introducing tighter controls on high risk offenders. Psychiatrists have always contributed to public protection by detaining dangerous patients. Yet proposed mental health legislation emphasising public protection has provoked an outcry.1 The government is accused of circumventing human rights legislation by concealing preventive detention in medical disguise, with establishment figures in forensic psychiatry even urging withdrawal from psychiatry's already limited participation in public protection.2–4 The Royal College of Psychiatrists has stated unequivocally that the only rationale for psychiatric intervention is for the benefit of patients' health and public protection is secondary. 5 The rhetoric should now cool while psychiatry determines its role in an alternative public protection framework.

The debate's moral focus has largely neglected two pragmatic questions. Firstly, is the health service equipped to take the lead in public protection? Secondly, can the philosophy underpinning strategy of the Department of Health for mental health be reconciled to the public protection agenda of the Home Office?

Many …
BASOPHIL COUNTS IN PATIENTS WITH URTICARIA, TREATED WITH ORAL ANTIHISTAMINES.
Authors: T. W. E. ROBINSON, J. H. PENNINGTON
Journal: British Journal of Dermatology (1966)

Journal Article BASOPHIL COUNTS IN PATIENTS WITH URTICARIA, TREATED WITH ORAL ANTIHISTAMINES. Get access T. W. E. ROBINSON, B.A., M.B., M.R.C.P., T. W. E. ROBINSON, B.A., M.B., M.R.C.P. Senior Registrar, Department of Dermatology, St. Bartholomew's Hospital, London Search for other works by this author on: Oxford Academic Google Scholar J. H. PENNINGTON, M.A., M.B., B. Chir. J. H. PENNINGTON, M.A., M.B., B. Chir. Lecturer, Department of Bacteriology, St. Bartholomew's Hospital, London Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 78, Issue 8-9, 1 August 1966, Pages 472–475, https://doi.org/10.1111/j.1365-2133.1966.tb12252.x Published: 01 August 1966