Lymphoblastic Lymphoma, A Term Rekindled with New Precision
Authors: ELAINE S. JAFFE
Journal: Annals of Internal Medicine (1978)

Editorials1 September 1978Lymphoblastic Lymphoma, A Term Rekindled with New PrecisionELAINE S. JAFFE, M.D., COSTAN W. BERARD, M.D.ELAINE S. JAFFE, M.D.Search for more papers by this author, COSTAN W. BERARD, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-89-3-415 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIt has been recognized for many years that some children with non-Hodgkin's lymphoma present with a characteristic distribution of supradiaphragmatic disease (1-6). Any combination of cervical, supraclavicular, or axillary lymph nodes may be involved, often with an anterior mediastinal mass or a pleural effusion containing neoplastic cells, or both. It has been known that a high percentage (30% to 50%) of such children developed acute leukemia if they have lived more than 2 to 3 months (3-6). Long before the discovery of T- and B-lymphoid cells, a relation was postulated between these tumors and the thymus gland (3). The progression...References1. ROSENBERGDIAMONDDARGEONCRAVER SHHL: Lymphosarcoma in children. N Engl J Med 259:505-512, 1958 CrossrefMedlineGoogle Scholar2. BAILEYBURGERTDAHLIN RED: Malignant lymphoma in children. Pediatrics 28:985-992, 1961 MedlineGoogle Scholar3. WEBSTER R: Lymphosarcoma of the thymus: its relation to acute lymphatic leukaemia. Med J Aust 48:582-586, 1961 CrossrefMedlineGoogle Scholar4. DAVISMCCREADIE LS: The enlarged thymus gland in leukemia in childhood. Am J Roentgenol 88:924-927, 1962 Google Scholar5. SULLIVAN M: Leukemic transformation in lymphosarcoma of childhood. Pediatrics 29:589-599, 1962 MedlineGoogle Scholar6. JONESKLINGBERG BW: Lymphosarcoma in children. A report of 43 cases and review of the recent literature. J Pediatr 63:11-20, 1963 CrossrefMedlineGoogle Scholar7. SMITHBARKERCLEINCOLLINS JCGR: Characterisation of malignant mediastinal lymphoid neoplasm (Sternberg sarcoma) as thymic in origin. Lancet 1:74-77, 1973 CrossrefMedlineGoogle Scholar8. RAPPAPORT H: Tumors of the hematopoietic system, in Atlas of Tumor Pathology, Section 3, Fascicle 8. Washington, D.C, U.S. Armed Forces Institute of Pathology, 1966 Google Scholar9. BERARD C: Histopathology of the lymphomas, in Hematology, edited by WILLIAMS WJ, BEUTLER E, ERSLEV AJ, RUNDLES RW. New York, McGraw-Hill, 1972, pp. 901-912 Google Scholar10. FIALKOWKLEINKLEINCLIFFORDSINGH PEGPS: Immunoglobulin and glucose-6-phosphate dehydrogenase as markers of cellular origin in Burkitt lymphoma. J Exp Med 138:89-102, 1973 CrossrefMedlineGoogle Scholar11. LUKESCOLLINS RR: Immunologic characterization of human malignant lymphomas. Cancer 34 (suppl): 1488-1503, 1974 CrossrefGoogle Scholar12. KAPLANMASTRANGELOPETERSON JRW: Childhood lymphoblastic lymphoma, a cancer of thymus-derived lymphocytes. Cancer Res 34:521-525, 1974 MedlineGoogle Scholar13. KERSEYSABADGAJL-PECZALSKA JAK: Neoplastic cells from childhood lymphoblastic leukemia and lymphoma with T and B lymphocyte markers (abstract). Am J Pathol 74:64, 1974 Google Scholar14. BARCOSLUKES MR: Malignant lymphoma of convoluted lymphocytes: a new entity of possible T-cell type, in Conflicts in Childhood Cancer: An Evaluation of Current Management. Proceedings, edited by SINKS LF, GODDEN JO. New York, Alan R. Liss, Inc., 1975, pp. 147-178 Google Scholar15. SENBORELLA LL: Clinical importance of lymphoblasts with T markers in childhood acute leukemia. N Engl J Med 292:828-832, 1975 CrossrefMedlineGoogle Scholar16. COCCIAKERSEYGAJL-PECZALSKAKRIVITNESBIT PJKWM: Prognostic significance of surface marker analysis in childhood non-Hodgkin's lymphoproliferative malignancies. Am J Hematol 1:405-417, 1976 CrossrefMedlineGoogle Scholar17. JAFFEBRAYLANFRANKGREENBERARD ERMIC: Heterogeneity of immunologic markers and surface morphology in childhood lymphoblastic lymphoma. Blood 48:213-222, 1976 CrossrefMedlineGoogle Scholar18. STEINPETERSENGAEDICKELENNERTLANDBECK HNGKG: Lymphoblastic lymphoma of convoluted or acid phosphatase type—tumor of T precursor cells. Int J Cancer 17:292-295, 1976 CrossrefMedlineGoogle Scholar19. TSUKIMOTOWONGLAMPKIN IKB: Surface markers and prognostic factors in acute lymphoblastic leukemia. N Engl J Med 294:245-248, 1976 CrossrefMedlineGoogle Scholar20. NATHWANIKIMRAPPAPORT BHH: Malignant lymphoma, lymphoblastic. Cancer 38:964-983, 1976 CrossrefMedlineGoogle Scholar21. DOWBORELLASENAURGEORGEMAUERSIMONE LLLRSAJ: Initial prognostic factors and lymphoblasterythrocyte rosette formation in 109 children with acute lymphoblastic leukemia. Blood 50:671-682, 1977 CrossrefMedlineGoogle Scholar22. DONLONJAFFEBRAYLAN JER: Terminal deoxynucleotidyl transferase activity in malignant lymphomas. N Engl J Med 297:461-464, 1977 CrossrefMedlineGoogle Scholar23. KUNGLONGMCCAFFREYRATLIFFHARRISONBALTIMORE PJRRTD: Terminal deoxynucleotidyl transferase in the diagnosis of leukemia and malignant lymphoma. Am J Med 64:788-794, 1978 CrossrefMedlineGoogle Scholar24. JAFFEBRAYLANNANBAFRANKBERARD ERKMC: Functional markers: a new perspective on malignant lymphomas. Cancer Treat Rep 61:953-962, 1977 MedlineGoogle Scholar25. BERARDO'CONORTHOMASTORLONI CGLH (eds.): Histopathological definition of Burkitt's tumor. Bull WHO 40:601-607, 1969 MedlineGoogle Scholar26. BENNETTCATOVSKYDANIELFLANDRINGALTONGRALNICKSULTAN JDMGDHC: Proposals for the classification of the acute leukaemias. French-American-British (FAB) co-operative group. Br J Haematol 33:451-458, 1976 CrossrefMedlineGoogle Scholar27. BROUETVALENSIDANIELFLANDRINPREUD'HOMMESELIGMANN JFMGJM: Immunological classification of acute lymphoblastic leukemias: evaluation of its clinical significance in a hundred patients. Brit J Hem 33:319-328, 1976 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Hematopathology Section Laboratory of Pathology National Cancer Institute Bethesda, Maryland PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByUnusual extramedullary hematopoietic neoplasms in lymph nodesUnusual lymphoblastic leukemia/lymphoma in Eastern IranTreatment of lymphoblastic lymphoma in adultsCutaneous involvement in lymphoblastic lymphomaThymic lymphoblastic lymphoma of committed natural killer cell precursor origin: A case reportAdult Lymphoblastic Lymphoma: Clinical Features and Prognostic Factors in 53 PatientsNon-Hodgkin's lymphomaLymphoblastic lymphoma presenting in cutaneous sitesImmune markers in hematologic malignanciesImmunohistochemical diagnosis of lymphoproliferative diseasesCell Surface Markers in Leukemia and LymphomaB-Cell Monoclonal Antibodies and Their Use in Clinical OncologySurface immunoglobulin-positive lymphoblastic lymphoma a report of three casesImprint cytology of non-Hodgkin's lymphomas based on a study of 212 immunologically characterized cases: Correlation of touch imprints with tissue sectionsLaboratory and clinical applications of monoclonal antibodies for leukemias and non-Hodkin's lymphomaCritical review of cancer epidemiology in petroleum industry employees, with a quantitative meta-analysis by cancer siteHistological and immunohistological analysis of human lymphomasImmunologic approaches to the classification of lymphomas and lymphoid leukemiasImmunologic approaches to the classification of non-Hodgkin’s lymphomasAutologous bone marrow transplantation in acute leukemia and lymphoma following ex vivo treatment with monoclonal antibodies and complementImmunologic classification of lymphoma and lymphoid leukemiaAn industry wide mortality study of chemical workers occupationally exposed to benzene. I. General results.Biphenotypic lymphoblastic lymphoma. An unusual tumor with lymphocytic and granulocytic differentiationImmunohistological subtypes of non-hodgkin's lymphoma in Hong Kong ChineseNucleoside transport and cytosine arabinoside (araC) metabolism in human T lymphoblasts resistant to araC, thymidine and 6-methylmecaptopurine ribosideMaligne Systemerkrankungen (bei Erwachsenen !)The hematologic malignancies: Leukemia, lymphoma, and myelomaPseudonodular T cell lymphoblastic lymphomaPh 1 -positive and Ph 1 -negative abnormal cell lines in a child with lymphoblastic lymphomaNon-Hodgkin's lymphoma in childrenA Review of Evidence that the Feline Leukemia Virus (FeLV) might be causative in Childhood Acute Lymphocytic Leukemia (ALL)Expression of Normal Differentiation Antigens on Human Leukemias and LymphomasA Review of Evidence that the Feline Leukemia Virus (FeLV) might be causative in Childhood Acute Lymphocytic Leukemia (ALL)Primary Non-Hodgkin's lymphoma of the mediastinumLymphoblastic lymphoma: Cytogenetic, pathologic, and immunologic studiesThe treatment of lymphoblastic lymphoma with antithymocyte globulinMalignant lymphoma of the skin: a review of recent advances in diagnosis and classificationExtranodal lymphoma: Surgical and other therapeutic alternativesKlinik der malignen LymphomeLymphoblastic lymphoma: A clinicopathologic study of 95 patientsBurkitt's LymphomaCase 36-1981Lymphoblastic lymphoma in adultsNephrotic syndrome associated with T-cell lymphomaPseudonodular pattern of T-cell lymphomaBone marrow involvement in Burkitt's lymphoma and its relationship to acute B-cell leukemiaA critical analysis of the classifications of non-Hodgkin's lymphomasClinico-Pathologic Correlation in non-Hodgkin's Lymphoma: I. Retrospective analysis using the Lukes and Collins classificationClinico-Pathologic Correlation in Non-Hodgkin's Lymphoma: III. Biologic significance of a modified Lukes and Collins classificationTreatment of Lymphoblastic Lymphoma in Adults 1 September 1978Volume 89, Issue 3Page: 415-417KeywordsCellsChildrenLymph nodesPleural effusionPrecursor cellsThymus Issue Published: 1 September 1978 PDF DownloadLoading ...