Coincidental Myxoedema and Pernicious Anaemia with Subsequent Development of Polycythaemia after Vitamin B_12 Therapy
Authors: VERONICA HALMOS
Journal: Annals of Internal Medicine (1961)

Case Reports1 August 1961Coincidental Myxoedema and Pernicious Anaemia with Subsequent Development of Polycythaemia after Vitamin B12 TherapyVERONICA HALMOS, M.D., F.R.C.P.(C), ROBERT VOLPÉ, M.D., F.R.C.P.(C)VERONICA HALMOS, M.D., F.R.C.P.(C)Search for more papers by this author, ROBERT VOLPÉ, M.D., F.R.C.P.(C)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-55-2-301 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThis communication reports a patient with coincident myxoedema and pernicious anaemia, who subsequently developed polycythaemia when therapy was instituted for the two diseases.The clinical similarities of pernicious anaemia and myxoedema (1, 2) and their occasional coexistence (2-7) have long been noted. Although a non-megaloblastic macrocytic anaemia which responds only to thyroid therapy is frequently observed in myxoedema (3, 8, 9), there are now well-authenticated case reports in which true pernicious anaemia and myxoedema were coexistent (3-7). The anaemic states in these patients did not respond to thyroid therapy until liver or vitamin B12therapy had been added. It should...References1. PITFIELD RL: Myxedema and the nervous system. Amer. J. Med. Sci. 151: 409, 1916. CrossrefGoogle Scholar2. MEANSLERMANCASTLE JHJWB: The coexistence of myxedema and pernicious anemia. New Engl. J. Med. 204: 243, 1931. CrossrefGoogle Scholar3. LEONARDFALCONERELLENHORN MEEHMJ: The anemia of myxedema, with special reference to pernicious anemia. Ann. Intern. Med. 34: 1251, 1951. LinkGoogle Scholar4. GREENE JA: A comparison of the symptoms, physical and laboratory findings of myxedema and pernicious anemia, with a report of three cases. Ann. Intern. Med. 10: 622, 1936. LinkGoogle Scholar5. 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PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPolyglobulie und Polycythaemia veraDie megaloblastischen AnämienAnämien bei EndokrinopathienMegaloblastic Anemia Secondary to Folate Deficiency Associated with HypothyroidismJOHN D. HINES, M.D., CHARLES H. HALSTED, M.D., ROBERT C. GRIGGS, M.D., JOHN W. HARRIS, M.D.PolycythemiaMegaloblastic Anaemia in Association with Polycythaemia VeraDEVELOPMENT OF POLYCYTHEMIA VERA AFTER TREATMENT FOR PERNICIOUS ANEMIA: REPORT OF A CASE 1 August 1961Volume 55, Issue 2Page: 301-306KeywordsAnemiaHemoglobinHospital medicineLiverMegaloblastic anemiaPolycythemiaProteinsResearch laboratoriesStenosisThyroid ePublished: 1 December 2008 Issue Published: 1 August 1961 PDF downloadLoading ...