Cholangiopathy Associated with <i>Microsporidia</i> Infection of the Common Bile Duct Mucosa in a Patient with HIV Infection
Authors: Laurent Beaugerie, Marie-Françoise Teilhac, Anne-Marie Deluol, Jacques Fritsch, Pierre-Marie Girard, Willy Rozenbaum, Yves Le Quintrec, François-Patrick Chatelet
Journal: Annals of Internal Medicine (1992)

Brief Reports1 September 1992Cholangiopathy Associated with Microsporidia Infection of the Common Bile Duct Mucosa in a Patient with HIV InfectionLaurent Beaugerie, MD, Marie-Françoise Teilhac, MD, Anne-Marie Deluol, MD, Jacques Fritsch, MD, Pierre-Marie Girard, MD, Willy Rozenbaum, MD, Yves Le Quintrec, MD, François-Patrick Chatelet, MDLaurent Beaugerie, MDSearch for more papers by this author, Marie-Françoise Teilhac, MDSearch for more papers by this author, Anne-Marie Deluol, MDSearch for more papers by this author, Jacques Fritsch, MDSearch for more papers by this author, Pierre-Marie Girard, MDSearch for more papers by this author, Willy Rozenbaum, MDSearch for more papers by this author, Yves Le Quintrec, MDSearch for more papers by this author, François-Patrick Chatelet, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-117-5-401 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptCholangiopathy has been described in patients with the acquired immunodeficiency syndrome (AIDS), often in association withCryptosporidiumorCytomegalovirusinfection (1, 2), or both. More recently, intestinal microsporidiosis due toEnterocytozoon bieneusiwas found to be the cause in about 30% of the cases of unexplained diarrhea (3). One case of periductular hepatic microsporidiosis in association with AIDS-related cholangiopathy has been recently reported (4), but the role of the parasite in the pathogenesis of cholangiopathy was unclear. We report the case of a patient with HIV-1 infection andMicrosporidia-caused diarrhea who developed cholangiopathy associated with Microsporidia infection of the common...References1. MargulisHonigSoaveGovoniMouradianJacobson SCRAJI. Biliary tract obstruction in the acquired immunodeficiency syndrome. Ann Intern Med. 1986;105:207-10. LinkGoogle Scholar2. Cello J. Acquired immunodeficiency syndrome cholangiopathy: spectrum of disease. Am J Med. 1989;86:539-46. CrossrefMedlineGoogle Scholar3. Eeftinck Schattenkerkvan Goolvan KetelBartelsmanKuikenTerpstra JTRJCW. Clinical significance of small-intestinal microsporidiosis in HIV-1-infected individuals. Lancet. 1991;337:895-8. CrossrefMedlineGoogle Scholar4. McWhinneyNathwaniGreenBoydForrest PDSJJ. Microsporidiosis detected in association with AIDS-related sclerosing cholangitis [Letter]. AIDS. 1991;5:1394-5. CrossrefMedlineGoogle Scholar5. FriedbergStensonOrensteinTiernoCharles DSJPN. Microsporidial keratoconjunctivis in acquired immunodeficiency syndrome. Arch Ophthalmol. 1990;108:504-8. CrossrefMedlineGoogle Scholar6. TeradaReddyJeffersCaliSchiff SKLAE. Microsporidian hepatitis in the acquired immunodeficiency syndrome. Ann Intern Med. 1987;107:61-2. LinkGoogle Scholar7. ZenderArrigoniEckertKapanci HEJY. A case of Encephalitozoon cuniculi peritonitis in a patient with AIDS. Am J Clin Pathol. 1989;92:352-6. CrossrefMedlineGoogle Scholar8. DesportesLe CharpentierGalian BernardCochand-PriolletLavergne IYAFBA. Occurrence of a new microsporidian Enterocytozoon bieneusi n.g.n.sp. in the enterocytes of a human patient with AIDS. J Protozool. 1985;32:250-4. CrossrefMedlineGoogle Scholar9. GreensonBelitsosYardleyBartlett JPJJ. AIDS enteropathy: occult enteric infections and duodenal mucosal alterations in chronic diarrhea. Ann Intern Med. 1991;114:366-72. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: From Hôpital Rothschild, Paris, France; and Hôpital Bicêtre, Le Kremlin-Bicêtre, France. For current author addresses, see end of text. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByThe Liver in Systemic Disease and PregnancyAkute und chronische HepatitisProtozoan ParasitesLiver and Bile Duct InfectionsNon-Hepatotropic Viral, Bacterial, and Parasitic Infections of the LiverThe Liver in Systemic Disease and PregnancyMicrosporidiosis in HumansMicrosporidiosisClinical Syndromes Associated with MicrosporidiosisLaboratory Diagnosis of MicrosporidiaHistoric Perspective on the Microsporidia: Expanding HorizonsLaboratory Diagnosis of MicrosporidiosisClinical Syndromes Associated with MicrosporidiosisProtozoan ParasitesOther viral and infectious diseases and HIV-related liver diseaseMicrosporidiosisOptimal CD8 T-Cell Response against Encephalitozoon cuniculi Is Mediated by Toll-Like Receptor 4 Upregulation by Dendritic CellsMicrosporidiosisMicrosporidiosisThe Liver in Systemic Disease and PregnancyLiver and Bile Duct InfectionsPrevalence and molecular characteristics of Enterocytozoon bieneusi in cattle in KoreaHistopathologic Classification of Liver PathologiesParasitic Diseases of Nonhuman PrimatesHistopathologic and Radiologic Classification of Liver PathologiesMicrosporidia and acquired immunodeficiency syndromeCHOLANGIOPATHY IN HIV-INFECTED PATIENTSMolecular Techniques for Detection, Species Differentiation, and Phylogenetic Analysis of MicrosporidiaLocalization of Persistent Enterocytozoon bieneusi Infection in Normal Rhesus Macaques ( Macaca mulatta ) to the Hepatobiliary TreeMicrosporidial Disease in HIV-infected Patients: A Report of 42 Patients and Review of the LiteraturePancreatic abnormalities and AIDS related sclerosing cholangitis.Microsporidiose au cours du SIDA, une infection opportuniste d'actualitéTHE PANCREAS IN AIDSWaterborne protozoan pathogensCeliac Plexus Block As Treatment for Refractory Pain Related to Sclerosing Cholangitis in AIDS PatientsComparative Development of Two Microsporidian Species: Enterocytozoon bieneusi and Enterocytozoon salmonis, Reported in AIDS Patients and Salmonid Fish, RespectivelyHuman microsporidiosis: Clinical, diagnostic and therapeutic aspects of an increasing infectionHuman antiprotozoal therapy: past, present, and futureLes microsporidioses en pathologie humaineHuman immunodeficiency virus 1—associated necrotizing cholangitis caused by infection with Septata intestinalisMicrosporidia and diarrhea in AIDS patientsHuman microsporidial infectionsA new trichrome-blue stain for detection of microsporidial species in urine, stool, and nasopharyngeal specimensHuman microsporidiosisElectron microscopic changes in Enterocytozoon bieneusi following treatment with albendazole.Biliary tract pathology in patients with AIDS. 1 September 1992Volume 117, Issue 5Page: 401-402KeywordsAIDSBile ductsCryptosporidiumCytomegalovirus infectionDiarrheaHIV infectionsHIV-1MicrosporidiosisMucous membranesPathogenesis Issue Published: 1 September 1992 PDF DownloadLoading ...