Angina-Like Chest Pain Without Identifiable Cause
Authors: MICHAEL V. HERMAN
Journal: Annals of Internal Medicine (1973)

Editorial1 September 1973Angina-Like Chest Pain Without Identifiable CauseMICHAEL V. HERMAN, M.D., F.A.C.P., PETER F. COHN, M.D., F.A.C.P., RICHARD GORLIN, M.D., F.A.C.P.MICHAEL V. HERMAN, M.D., F.A.C.P., PETER F. COHN, M.D., F.A.C.P., RICHARD GORLIN, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-79-3-445 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAngina Pectoris is a symptom complex originally described by Heberden some 200 years ago. Although his description of the pain has not really been improved on, its precise causation has remained partly in doubt. It has been associated with various forms of heart disease, including coronary atherosclerosis, valvular heart disease, and hypertension of either the pulmonary or systemic circuits. Less common disorders that have been most recently identified have been vasculitis and cardiomyopathy, particularly of the hypertrophic variety. The common denominator in each disorder is an imbalance between cardiac contractile effort and available oxygen supply, either global or segmental in...References1. ZOLL P, WESSLER S, and BLUMGART H: Angina pectoris, a clinical and pathologic correlation. Am J Med 11:331-357, 1951 CrossrefMedlineGoogle Scholar2. LIKOFF W, SEGAL B, and KASPARIAN H: Paradox of normal selective coronary arteriograms in patients considered to have unmistakable coronary heart disease. N Engl J Med 276:1063-1066, 1967 CrossrefMedlineGoogle Scholar3. KEMP H, ELLIOTT W, and GORLIN R: The anginal syndrome with normal coronary arteriography. Trans Assoc Am Physicians 80:59-70, 1967 MedlineGoogle Scholar4. BEMILLER C, PEPINE C, and ROGERS A: Long-term observations in patients with angina and normal coronary arteriograms. Circulation 47:36-43, 1973 CrossrefMedlineGoogle Scholar5. KEMP H, VOKONAS P, and COHN P: The anginal syndrome associated with normal coronary arteriograms—report of a six year experience. Am J Med. 54:735-742, 1973 CrossrefMedlineGoogle Scholar6. COHN P, GORLIN R, and VOKONAS P: A quantitative clinical index for the diagnosis of symptomatic coronary artery disease. N Engl J Med 286:901-907, 1972 CrossrefMedlineGoogle Scholar7. ELIOT R and BRATT G: The paradox of myocardial ischemia and necrosis in young women with normal coronary arteriograms. Relation to abnormal hemoglobin-oxygen dissociation. Am J Cardiol 23:633-638, 1969 CrossrefMedlineGoogle Scholar8. VOKONAS P, COHN P, and KLEIN M: Hemoglobin affinity for oxygen in the anginal syndrome with normal coronary arteriograms. Am J Cardiol 26:664, 1970 CrossrefGoogle Scholar9. JAMES T: Angina without coronary disease (sic). Circulation 42:189-191, 1970 CrossrefMedlineGoogle Scholar10. KREULEN T, GORLIN R, and HERMAN M: Ventriculographic patterns and hemodynamics in primary myocardial disease. Circulation 47:299-308, 1973 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: MICHAEL V. HERMAN, M.D., F.A.C.P.; PETER F. COHN, M.D., F.A.C.P.; RICHARD GORLIN, M.D., F.A.C.P.Affiliations: Cardiovascular Division Department of Medicine Peter Bent Brigham Hospital and Harvard Medical School Boston, Massachusetts PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byClinical Significance of the Calcification of Coronary Arteries in Patients with Angiographically Normal Coronary ArteriesBibliographyExercise-induced impairment of diastolic time in patients with X syndromeChest pain of esophageal originVisualization of subendocardial myocardial ischemia with myocardial contrast echocardiography in humans.Hypertrophische obstruktive Kardiomyopathie (HOCM)Hypertrophische nicht obstruktive Kardiomyopathie (HNCM)Latente Kardiomyopathie (LCM)Connecting the ceruleus and the coronaries"Microvascular angina" as a cause of chest pain with angiographically normal coronary arteriesInfluence of the normal personality dimension of neuroticism on chest pain symptoms and coronary artery diseaseIs Neuroticism A Risk Factor for CAD? 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