Diltiazem and Hyperactivity
Authors: DOUGLAS D. BRINK
Journal: Annals of Internal Medicine (1984)

Letters and Corrections1 March 1984Diltiazem and HyperactivityDOUGLAS D. BRINK, PHARM.D.DOUGLAS D. BRINK, PHARM.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-100-3-459_3 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: I read with interest Dr. Jacob's report (1) of a patient who developed what appeared to be akathisia while being treated with the newest calcium antagonist, diltiazem. Increased physical activity and subjective feelings of unabating restlessness have not been previously reported as side effects of diltiazem. I recently began treating a patient who had a similar problem while being treated with diltiazem. However, our patient, a 56-year-old man with no history of psychiatric problems, was slower in developing behavioral changes that the patient described by Dr. Jacobs, and the changes that ultimately occurred were of a more...References1. JACOBS M. Diltiazem and akathisia. Ann Intern Med. 1983;99:794-5. LinkGoogle Scholar2. STRAUSSMCINTYREPARISISHAPIRO WKAW. Safety and efficacy of diltiazem hydrochloride for the treatment of stable angina pectoris: report of a cooperative clinical trial. Am J Cardiol. 1982;49:560-6. CrossrefMedlineGoogle Scholar3. STONEANTMANMULLERBRAUNWALD PEJE. Calcium channel blocking agents in the treatment of cardiovascular disorders: Part II. Hemodynamic effects and clinical applications. Ann Intern Med. 1980;93:886-904. LinkGoogle Scholar4. LEWIS J. Adverse reactions to calcium antagonists. Drugs. 1983;25:196-222. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: DOUGLAS D. BRINK, PHARM.D.Affiliations: Veterans Administration Medical Center Hampton, VA 23667 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byCalcium channel blockersPSYCHOLOGICAL AND PSYCHIATRIC ADVERSE EFFECTS OF NON-PSYCHOACTIVE DRUGSDrugs Used to Treat Hypertension, Heart Failure, and Angina PectorisCalcium channel blockersUnerwünschte Wirkungen von Calciumantagonisten unter besonderer Berücksichtigung der Verträglichkeit von GallopamilSide Effects — Overdosage — Contraindications — Drug InteractionsBehavioral effects of diltiazem injected into the paraventricular nucleus of the hypothalamusNebenwirkungen — Überdosierung (Vergiftung) — Kontraindikationen — ArzneimittelinteraktionenAdrenoreceptors and the pharmacology of affective illness: A unifying theoryAggression and defeat-induced opioid analgesia displayed by mice are modified by calcium channel antagonists and agonistsCalcium Antagonists: A New Class of Psychiatric Drugs?A negative, double-blind, placebo-controlled, clinical trial of verapamil in chronic schizophreniaCalcium Channel blockers: Spectrum of Side Effects and Drug InteractionsDifferences between calcium channel inhibitors in their effects on phencyclidine-induced behavioral stimulation in miceAntianginal and β-adrenoceptor blocking drugs 1 March 1984Volume 100, Issue 3Page: 459-460KeywordsCalciumEmotionsExercise ePublished: 1 December 2008 Issue Published: 1 March 1984 PDF downloadLoading ...