An Unusual Case of Brucellar Osteomyelitis Associated with Serum Blocking Antibody Activity
Authors: W. E. BULLOCK
Journal: Annals of Internal Medicine (1964)

Case Studies1 November 1964An Unusual Case of Brucellar Osteomyelitis Associated with Serum Blocking Antibody ActivityW. E. BULLOCK, M.D., L. G. TOBIAN, M.D., P. M. ARNESEN, M.D.W. E. BULLOCK, M.D.Search for more papers by this author, L. G. TOBIAN, M.D.Search for more papers by this author, P. M. ARNESEN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-61-5-938 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptApproximately 10 to 15% of those who contract acute brucellosis will still be disabled a year or more after the onset of their illness (1). This is true both for untreated cases and those receiving appropriate antibiotic therapy. Such chronicity is largely related to the presence of localizing complications, often associated with several relapses. Brucella suis is the species most likely to cause a form of human illness that is complicated by chronic suppurative lesions of bones, joints, and parenchymal tissues (2). It is the purpose of this report to present an unusual case of osteomyelitis due to Br. suis...References1. SPINK WW: What is chronic brucellosis? Ann. Intern. Med. 35: 358, 1951. LinkGoogle Scholar2. BRAUDE AI: Brucellosis. Disease—A-Month Series. December: 19: 1957. Google Scholar3. KLIMMERHAUPT MH: Über die durch das corynebacterium abortus Bang verusachte Erkrankung des Meerschweinchens. Virchow. Arch. Path. Anat. 242: 350, 1923. CrossrefGoogle Scholar4. LOWBEER L: Skeletal and articular involvement in brucellosis of animals. Lab. Invest. 8: 1448, 1959. MedlineGoogle Scholar5. COVENTRYIVINSNICHOLSWEED MBJCDRLA: Infection of the hip by Brucella suis. JAMA 141: 320, 1949. CrossrefMedlineGoogle Scholar6. SPINK WW: The Nature of Brucellosis. University of Minnesota Press, Minneapolis, 1956, p. 180. Google Scholar7. HARDYJORDANBORTSHARDY AVCFIHGC: Undulant fever: with special reference to a study of Brucella infections in Iowa. Nat. Inst. Hlth. Bull. 158: 76, 1931. Google Scholar8. MARTINNICHOLSBEAHRS WJDROH: Chronic localized brucellosis. Arch. Intern. Med. (Chicago) 107: 75, 1961. CrossrefMedlineGoogle Scholar9. KELLYMARTINSCHURGERWEED PJWJALA: Brucellosis of the bones and joints—experience with thirty-six patients. JAMA 174: 347, 1960. CrossrefMedlineGoogle Scholar10. ZINNEMANSEALHALL HHUSWH: Some molecular characteristics of blocking antibodies in human brucellosis. To be published in J. Immun. January, 1965. Google Scholar11. ZINNEMANGLENCHURHALL HHHWH: The nature of blocking antibodies in human brucellosis. J. Immun. 83: 206, 1959. MedlineGoogle Scholar12. HALLMANION WHRE: Comparison of the Coombs test with other methods for brucella agglutinins in human serum. J. Clin. Invest. 32: 96, 1953. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Minneapolis, MinnesotaFrom the Departments of Medicine and Orthopedic Surgery, University of Minnesota Medical School, Minneapolis, Minn.Requests for reprints should be addressed to W. E. Bullock, M.D., U. S. Naval Medical Research Unit #2, Box 14, A.P.O. 63, San Francisco, Calif. 96263. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited BySection E. Diseases of dairy cattle. Brucellosis 1 November 1964Volume 61, Issue 5_Part_1Page: 938-943KeywordsAntibioticsBoneBrucellaBrucellosisLesionsOrthopedic surgeryOsteomyelitisResearch laboratories Issue Published: 1 November 1964 PDF DownloadLoading ...