Uremic Pneumonitis
Authors: ROBERT I. HENKIN
Journal: Annals of Internal Medicine (1962)

Case Studies1 December 1962Uremic PneumonitisA Clinical, Physiological StudyROBERT I. HENKIN, M.D., MORTON H. MAXWELL, M.D., JOHN F. MURRAY, M.D.ROBERT I. HENKIN, M.D., MORTON H. MAXWELL, M.D., JOHN F. MURRAY, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-57-6-1001 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe pathogenesis and histological characteristics of uremic pneumonitis have not been well defined. Indeed, the suggestion has been made that it exists not as a distinct clinical entity, but rather as a manifestation of cardiac failure in the uremic patient (1-7). We have had the opportunity to study a patient in whom 5 episodes of uremic pneumonitis responded promptly to peritoneal dialysis. The results suggest that uremic pneumonitis does, indeed, exist as part of the pathophysiology of renal failure, and may occur without detectable evidence of cardiac decompensation.CASE REPORTA 21-year-old Caucasian male was admitted to the University of...References1. ROUBIERPLAUCHU CM: Sur certains aspects radiographiques de l'oedéme pulmonaire chez les cardiorénaux azotémiques. Arch. Med. Chir. App. Resp. 9: 189, 1934. Google Scholar2. KLIMAROSEGGER RH: Eigenartige Krankheitsbilder zufolge von Lungen-ödem bei Niereninsuffizienz. Med. Klin. 32: 85, 1936. Google Scholar3. RENDICHLEVYCOVE RAAHAM: Pulmonary manifestations of azotemia. Amer. J. Roentgenol. 46: 802, 1941. Google Scholar4. DONAICH I: Uremic edema of the lungs. Amer. J. Roentgenol. 58: 620, 1947. Google Scholar5. DEPASSSTEINPOPPELJACOBSEN SWJMHHG: Pulmonary congestion and edema in uremia. JAMA 162: 5, 1956. CrossrefMedlineGoogle Scholar6. JACKSON F: The radiology of acute pulmonary-oedema. Brit. Heart J. 13: 503, 1951. CrossrefMedlineGoogle Scholar7. DEFAZIOCHRISTENSENREGAN VRCTJ: Circulatory changes in acute glomerulonephritis. Circulation 20: 190, 1959. CrossrefMedlineGoogle Scholar8. MAXWELLROCKNEYKLEEMANTWISS MHRECRMR: Peritoneal dialysis. JAMA 170: 917, 1959. CrossrefMedlineGoogle Scholar9. SEVELIUSJOHNSON GPC: Myocardial blood flow determined by surface counting and ratio formula. J. Lab. Clin. Med. 54: 669, 1959. MedlineGoogle Scholar10. MENAKATTUSGREENFIELDBLAKELEYBENNETT IAAMAWRLR: Effect of coronary blood flow on radioisotope dilution curves measured by precordial scintillation detection. Circulat. Res. 9: 911, 1961. CrossrefMedlineGoogle Scholar11. LANGE W: Ueber eine eigenthümliche Erkrankung der kleinen Bronchien und Bronchiolen (Bronchitis und Bronchiditis obliterans). Deutsch. Arch. Klin. Med. 70: 342, 1901. Google Scholar12. EHRICHMCINTOSH WJF: The pathogenesis of bronchiolitis obliterans. Arch. Path. 13: 69, 1932. Google Scholar13. CAMERON GR: Pulmonary oedema. Brit. Med. J. 1: 965, 1948. CrossrefMedlineGoogle Scholar14. BASSSINGER HEE: Pulmonary changes in uremia. JAMA 144: 819, 1950. CrossrefMedlineGoogle Scholar15. BASSGREENBERGSINGERMILLER HEDEMA: Pulmonary changes in uremia. JAMA 148: 724, 1952. CrossrefMedlineGoogle Scholar16. HOPPSWISSLER HCRW: Uremic pneumonitis. Amer. J. Path. 31: 261, 1955. MedlineGoogle Scholar17. ALLEN AC: The Kidney, Grune & Stratton, Inc., New York, 1951, p. 76. Google Scholar18. RUBINKAHNPECKER EHBSD: Diffuse interstitial fibrosis of the lungs. Ann. Intern. Med. 36: 827, 1952. LinkGoogle Scholar19. LYNCHMELLORBADGERY MFLDAR: Hyaline membrane disease. J. Pediat. 48: 602, 1956. CrossrefMedlineGoogle Scholar20. ALLENSPITZ ACS: A comparative study of the pathology of scrub typhus (tsutsugamushi disease) and other rickettsial diseases. Amer. J. Path. 21: 603, 1945. MedlineGoogle Scholar21. REIMANN HA: The viral pneumonias and pneumonias of probable viral origin. Medicine 26: 167, 1947. CrossrefMedlineGoogle Scholar22. WARRENSPENSER SJ: Radiation reaction in the lung. Amer. J. Roentgenol. 43: 682, 1940. Google Scholar23. BERGMANNGRAHAM MEA: Pneumonectomy for severe irradiation damage of the lung. J. Thor. Cardiov. Surg. 22: 549, 1951. Google Scholar24. CAMERONCOURTICE GRFC: The production and removal of oedema fluid in the lung after exposure to carbonyl chloride (phosgene). J. Physiol. 105: 175, 1946. CrossrefGoogle Scholar25. GIBBONBRUNERBOCHELOCKWOOD MHHDRDJS: Studies on experimental phosgene poisoning. II. Pulmonary artery pressure in phosgene-poisoned cats. J. Thor. Cardiov. Surg. 17: 264, 1948. Google Scholar26. EPSTEINGREENSPAN EZEB: Rheumatic pneumonia. Arch. Intern. Med. 68: 1074, 1941. CrossrefGoogle Scholar27. SELDINKAPLANBUNTING DWHSH: Rheumatic pneumonia. Ann. Intern. Med. 26: 496, 1947. LinkGoogle Scholar28. CAMERONDE GRSN: Experimental pulmonary oedema of nervous origin. J. Path. Bact. 61: 375, 1949. CrossrefGoogle Scholar29. NESSARIGLER CBLG: The roentgenological manifestations of pulmonary edema. Radiology 37: 35, 1941. CrossrefGoogle Scholar30. RUBINTHOMAS EDED: Some relations between pulmonary edema and pulmonary inflammation (pneumonia). Arch. Intern. Med. 93: 713, 1954. CrossrefGoogle Scholar31. GAMBLEPATTON JEHD: Pulmonary edema and hemorrhage induced by hypothalamic lesions in the rat. Science 113: 626, 1951. CrossrefMedlineGoogle Scholar32. LUISADACARDI AAL: Acute pulmonary edema. Circulation 13: 113, 1956. CrossrefMedlineGoogle Scholar33. BARDENCOOPER RPDA: The roentgen appearance of the chest in diseases affecting the peripheral vascular system of the lungs. Radiology 51: 44, 1948. CrossrefMedlineGoogle Scholar34. GOODRICH WA: Pulmonary edema. A correlation of x-ray appearance and physiological changes. Radiology 51: 58, 1948. CrossrefMedlineGoogle Scholar35. ALWALLLUNDERQUISTOLSSON NAO: Studies on electrolyte-fluid retention. I. Uremic lung-fluid lung? On pathogenesis and therapy. (A preliminary report.) Acta Med. Scand. 146: 157, 1953. CrossrefMedlineGoogle Scholar36. LEMMONHIROSEO'CONNORBAILEY WMTRAC: Congestive heart failure-relief by renal dialysis. JAMA 174: 2124, 1960. CrossrefMedlineGoogle Scholar37. SCHNEIERSON SJ: Continuous peritoneal irrigation in treatment of intractable edema of cardiac origin. Amer. J. Med. Sci. 218: 76, 1949. CrossrefMedlineGoogle Scholar38. DAVIES CE: Heart failure in acute nephritis. Quart. J. Med. 20: 163, 1951. MedlineGoogle Scholar39. EICHNAFARBERBERGERRADERSMITHALBERT LWSJARBWWRE: Non-cardiac circulatory congestion simulating congestive heart failure. Trans. Ass. Amer. Physicians 67: 72, 1954. MedlineGoogle Scholar40. HENKINBYATTMAXWELL RIPHMH: Evidence for the presence of a dialyzable "toxic" factor in the sera of uremic subjects. Clin. Res. 9: 202, 1961. Google Scholar41. BORGSTROMISINGLINDERLUNDERQUIST KEUEA: Experimental pulmonary edema. Acta Radiol. (Stockh.) 54: 97, 1960. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Los Angeles, CaliforniaFrom the Department of Medicine, University of California Medical Center, Los Angeles, California.Requests for reprints should be addressed to Robert I. Henkin, M.D., Laboratory of Clinical Science, National Institute of Mental Health, Bethesda 14, Maryland. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByPulmonary Complications of Abdominal DiseasesCase 32-2012Pulmonary Complications of Abdominal DiseasePulmonary Complications After Acute Kidney InjuryPulmonary edema and other disorders in acute renal failureUremic PleuritisPulmonary Function and Arterial Blood Gas in the Long-Term Hemodialysis PatientUremic pulmonary edemaFunctional Characteristics of the Lung in Chronic Uremia Treated by Renal Dialysis TherapyEffects of Hemodialysis and Renal Transplantation on Pulmonary FunctionSekundäre maligne Tumoren der Bronchien und LungenOn some Problems of Intensive Therapy in Patients with Acute Renal FailureUremia: Newer Concepts in Pathogenesis and TreatmentHemodynamic Studies in Chronic UremiaPulmonary Disease of Vascular OriginManagement of chronic renal failurePulmonary Changes in Acute Experimental Uremia in RatsReferencesPROBLEMS IN THE MANAGEMENT OF ACUTE RENAL FAILURELung Clearance in Pulmonary Alveolar Proteinosis 1 December 1962Volume 57, Issue 6Page: 1001-1008KeywordsGlomerulonephritisHeart failureMedical dialysisPathogenesisPeritoneal dialysisPneumonitisRenal failure Issue Published: 1 December 1962 PDF DownloadLoading ...