tbuckley/cabot-search huggingface dataset:
Differential Influence of Maternal Smoking on Infant Birth Weight
Authors: George P. Vogler, Lynn T. Kozlowski
Journal: JAMA (2002)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Use of reperfusion therapy in patients presenting with ST elevation myocardial infarction: Findings from the TETAMI study and TETAMI registry (the safety and efficacy of subcutaneous enoxaparin versus intravenous unfractionated heparin and of tirofiban versus placebo in the treatment of acute myocardial infarction)
Authors: Gian Franco Gensini, Marc Cohen, Frans Maritz, Enrique P. Gurfinkel, Kurt Huber, Ari Timerman, Maria Krzeminska-Pakula, Nicolas Danchin, Harvey D. White, Luc Vittori
Journal: Journal of the American College of Cardiology (2003)
Protein-based phylogenies support a chimeric origin for the eukaryotic genome.
Authors: G. B. Golding, R. S. Gupta
Journal: Molecular Biology and Evolution (1995)

The phylogenetic position of the archaebacteria and the place of eukaryotes in the history of life remain a question of debate. Recent studies based on some protein-sequence data have obtained unusual phylogenies for these organisms. We therefore collected the protein sequences that were available with representatives from each of the major forms of life: the gram-negative bacteria, gram-positive bacteria, archaebacteria, and eukaryotes. Monophyletic, unrooted phylogenies based on these sequence data show that seven of 24 proteins yield a significant gram-positive-archaebacteria clade/gram-negative-eukaryotic clade. The phylogenies for these seven proteins cannot be explained by the traditional three-way split of the eukaryotes, archaebacteria, and eubacteria. Nine of the 24 proteins yield the traditional gram-positive-gram-negative clade/archaebacteria-eukaryotic clade. The remaining eight proteins give phylogenies that cannot be statistically distinguished. These results support the hypothesis of a chimeric origin for the eukaryotic cell nucleus formed from the fusion of an archaebacteria and a gram-negative bacteria.
GPs should not be solely responsible for assessing entitlement to benefits, MPs say
Authors: G. Iacobucci
Journal: BMJ (2014)

MPs have urged the government to seek evidence from a wider range of professionals, including social workers and occupational therapists, when assessing people’s claims for disability and long term sickness benefits, in a bid to reduce the burden on GPs.

The recommendation was one of several measures proposed in a new report from the House of Commons Work and Pensions Committee,1 which concluded that the current assessment process for employment and support allowance (ESA) was “not achieving its aims” and required a “fundamental redesign.”

Nearly all GPs in a recent survey carried out by The BMJ2 said that their workload had soared in the past year because of government changes to the ESA. Doctors said that they were increasingly asked to provide medical information about patients undergoing tougher …
Late clinical and angiographic outcome of bailout coronary stenting. A comparison study between Gianturco-Roubin and Palmaz-Schatz stents
Authors: Antonio Fernández-Ortiz, Javier Goicolea, Maria J. Perez-Vizcayno, Fernando Alfonso, Rosana Hernández, Camino Bañuelos, Javier Segovia, Adolfo Rodiguez, Carlos Macaya
Journal: Journal of the American College of Cardiology (1996)
The effect of perfusion on the flora of the excluded colon
Authors: A. Vince, R. Bown, F. O'Grady, A. M. Dawson
Journal: Gut (1973)

The bacterial flora of excluded colonic segments of three patients has been examined in the normal resting state and following perfusion.The flora of the excluded colon was substantial and qualitatively similar to that of faeces. Perfusion for two hours at 10 ml per minute usually reduced counts of organisms present in the issuing effluent by 1 to 1(1/2) logs in two patients, but rises in the counts of some organisms were recorded from the third patient. Prolonged rapid perfusion or the inclusion of antibiotics in the perfusing solution was necessary to obtain a substantial reduction in counts. Rapid perfusion resulted in the appearance of organisms that had not been recovered during slower perfusions.
The Evolving Science of Cochlear Implants
Authors: Graeme M. Clark, Jonathan C. M. Clark, John B. Furness
Journal: JAMA (2013)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
An Increased B-Type Natriuretic Peptide in the Absence of a Cardiac Abnormality Identifies Those Whose Left Ventricular Mass Will Increase Over Time
Authors: M. Adnan Nadir, Stephen Gandy, Sheila Ireland, Tom MacDonald, Ellie Dow, Graeme Houston, Chim Lang, Allan Struthers
Journal: JACC Heart Failure (2014)

The purpose of this study was to identify the relationship of B-type natriuretic peptide (BNP) with evolution of left ventricular mass (LVM) in optimally treated primary prevention patients. Patients who have an elevated BNP no cardiac abnormality on echocardiography are common and at increased risk of adverse events. One hypothesis is that an elevated BNP is an early sensitive indicator of who will develop future structural abnormalities such as left ventricular (LV) hypertrophy. We identified optimally treated primary prevention patients with no cardiac abnormality at baseline. In particular, they had no myocardial ischemia, LV hypertrophy, LV dysfunction, or left atrial enlargement. They had a diverse range of plasma BNP levels and underwent cardiac magnetic resonance at baseline and 3 years later on a 3-T scanner. Fifty patients with a diverse range of BNP were studied (with BNP ≤10 pg/ml in 25 patients and >10 pg/ml in 25 patients). LVM increased (+4.7 ± 3.5 g) in 24 patients and decreased (–4.9 ± 2.8 g) in 26 patients (p < 0.01). Blood pressure by 24-h monitoring was virtually identical between those whose LVM increased (systolic blood pressure 122 ± 14 mm Hg) and those whose LVM decreased (systolic blood pressure 121 ± 11 mm Hg, p = 0.77). Plasma BNP was nearly 3 times higher in those whose LVM increased versus those in whom LVM decreased (21 ± 9.6 pg/ml vs. 7.9 ± 3.9 pg/ml, p < 0.01). The c-statistic for BNP was 0.88. In optimally treated primary prevention patients, plasma BNP levels are able to distinguish between those whose LVM will increase during the next 3 years versus those whose LVM will decrease during the next 3 years. This may explain why individuals with high BNP are at increased risk even if no cardiac abnormality can be detected initially.
A Tumor of the Lung Featuring Increased Pulmonary Arterial Perfusion
Authors: YAMIL ABBUD, RALPH J. GORTEN
Journal: Clinical Nuclear Medicine (1982)

An area of relatively increased tracer activity on a perfusion lung scan was found in the same location as a radiodense lung mass. The lesion responsible for this unusual combination of findings was identified after lobectomy and tissue examination to be poorly differentiated adenosquamous carcinoma.
Older US women are less likely than men to get kidney transplants
Authors: J. H. Tanne
Journal: BMJ (2009)

Past attempts to visualize the internal structure of the spinal cord in vivo have been hampered by many factors, including the small size of the cord, the dense bony investiture of the spine, and the similarities of tissue densities from one region to another within the cord. Delayed CT is the imaging technique currently being used at our institution as an adjunct to iopamidol myelography to visualize the deep gray matter of the cord. This visualization is achieved by a poorly understood differential gray/white-matter enhancement, possibly due to either a shielding effect of the white matter as it envelops the gray matter, a differential absorption rate between gray and white matter, or a greater rate of reabsorption of contrast by the more highly vascularized gray matter. This method is not being advocated as a primary diagnostic technique due to the lack of reliability in providing successful results from section to section, from patient to patient, and from one time period of delay to the next. Instead, it is an initial attempt to image the basic, intrinsic structure of the spinal cord in vivo, which may herald a valuable advance in imaging methodology.
Preconception Maternal and Paternal Exposure to Persistent Organic Pollutants and Birth Size: The LIFE Study
Authors: Candace A. Robledo, Edwina Yeung, Pauline Mendola, Rajeshwari Sundaram, Jose Maisog, Anne M. Sweeney, Dana Boyd Barr, Germaine M. Buck Louis
Journal: Environmental Health Perspectives (2014)

Persistent organic pollutants (POPs) are developmental toxicants, but the impact of both maternal and paternal exposures on offspring birth size is largely unexplored.We examined associations between maternal and paternal serum concentrations of 63 POPs, comprising five major classes of pollutants, with birth size measures.Parental serum concentrations of 9 organochlorine pesticides, 1 polybrominated biphenyl (PBB), 7 perfluoroalkyl chemicals (PFCs), 10 polybrominated diphenyl ethers (PBDEs), and 36 polychlorinated biphenyls (PCBs) were measured before conception for 234 couples. Differences in birth weight, length, head circumference, and ponderal index were estimated using multiple linear regression per 1-SD increase in natural log-transformed (ln-transformed) chemicals. Models were estimated separately for each parent and adjusted for maternal age, maternal prepregnancy body mass index (kilograms per meter squared) and other confounders, and all models included an interaction term between infant sex and each chemical.Among girls (n = 117), birth weight was significantly lower (range, 84-195 g) in association with a 1-SD increase in ln-transformed maternal serum concentrations of DDT, PBDE congeners 28 and 183, and paternal serum concentrations of PBDE-183 and PCB-167. Among boys (n = 113), maternal (PCBs 138, 153, 167, 170, 195, and 209 and perfluorooctane sulfonamide) and paternal (PCBs 172 and 195) serum concentrations of several POPs were statistically associated with lower birth weight (range, 98-170 g), whereas paternal concentrations of PBDEs (66, 99) were associated with higher birth weight. Differences in offspring head circumference, length, and ponderal index were also associated with parental exposures.Preconceptional maternal and paternal concentrations of several POPs were associated with statistically significant differences in birth size among offspring.
Psoriasis: maintenance of an intact monolayer basal cell differentiation compartment in spite of hyperproliferation
Authors: I.M. LEIGH, K.A. PULFORD, F.C. SRAMAEKERS, E.B. LANE
Journal: British Journal of Dermatology (1985)

Frozen sections of punch biopsies from normal epidermis and psoriatic involved and uninvolved epidermis have been examined immunocytochemically using a panel of anti-keratin monoclonal antibodies with various specificities in the skin. Since psoriasis is thought to involve hyperproliferative expansion of the basal compartment from one to about three cell layers in thickness, the samples were screened with antibodies to intermediate filament determinants associated with basal cells, suprabasal cells and hyperproliferating keratinocyte-derived cell lines, respectively. The basal—suprabasal division was observed to be intact, with only one layer of basal cells demarcated by the specific antibodies used under all circumstances. this suggests that (a) psoriatic 'basal cell hyperproliferation' may not specifically involve the basal cell compartment containing the stem cells, but rather a population of amplifying transit cells which are predominantly suprabasal, and that (b) while keratinocyte differentiation begins as the cells lose contact with the basal lamina, the first stages at least of differentiation are not dependent on the loss of the capacity to divide.
Book Review Deceit and Denial: The Deadly Politics of Industrial Pollution (California/Milbank Books on Health and the Public.) By Gerald Markowitz and David Rosner. 408 pp., illustrated. Berkeley and New York, University of California Press and the Milbank Memorial Fund, 2002. $34.95. 0-520-21749-7
Authors: Robert N. Proctor
Journal: New England Journal of Medicine (2003)
A2-01: Prognostic significance of AJCC T2 descriptor-visceral pleura invasion, hilar atelectasis or obstructive pneumonitis for stage IB non-small-cell lung cancer (NSCLC) is dependent on tumor size
Authors: Sai-Hong I. Ou, Jason A. Zell, Argyrios Ziogas, Hoda Anton-Culver
Journal: Journal of Thoracic Oncology (2007)
Relation of risk factor levels in young adulthood to parental history of disease. The CARDIA study.
Authors: G L Burke, P J Savage, J M Sprafka, J V Selby, D R Jacobs, L L Perkins, J M Roseman, G H Hughes, R R Fabsitz
Journal: Circulation (1991)

BACKGROUND The relation between self-reported parental disease and risk factor levels was examined in 2,637 black and 2,478 white men and women aged 18-30 years at the Coronary Artery Risk Development in Young Adults (CARDIA) Study baseline examination (1985-1986). METHODS AND RESULTS The prevalence of parental disease (at least one parent) in white versus black participants was 44% and 56% for hypertension, 47% and 44% for obesity, 16% and 13% for myocardial infarction, 11% and 17% for diabetes, and 6% and 10% for stroke, respectively. Among these young adults, parental hypertension was associated with higher sex- and age-adjusted systolic and diastolic blood pressure levels. Parental myocardial infarction was associated with higher plasma cholesterol, higher blood pressure levels, and lower high density lipoprotein cholesterol levels in white participants. Parental diabetes was associated with higher fasting blood glucose and insulin levels in all race-sex groups and with higher triglycerides and lower high density lipoprotein cholesterol in black participants only. Parental history of obesity was related to less favorable age- and sex-adjusted lipid levels in white participants and higher blood pressure levels in black participants. Parental history of stroke was associated with higher systolic blood pressure levels in black participants. In general, these differences across family history were predicted only in part by obesity. The prevalence of more than one disease reported in parents occurred more frequently than would have been expected due to chance alone. CONCLUSIONS These associations between parental disease and risk factors in their adult children probably reflects the impact of both environmental and genetic factors. Parental history may be a useful marker for high risk individuals.
Nitroprusside after open-heart surgery.
Authors: G Benzing, J A Helmsworth, J T Schrieber, J Loggie, S Kaplan
Journal: Circulation (1976)

The effects of intravenous infusion of sodium nitroprusside were studied in 11 children immediately after open-heart surgery for congenital heart disease. The patients were selected because, following bypass, their cardiac index was below 2,0 L/min/m2 and their systemic vascular resistance exceeded 30 units. In order to eliminate the effects of preload, mean left atrial pressure was maintained at a constant level by blood transfusion. During infusion of nitroprusside the mean decrease of mean arterial pressure was 18.6%, of systemic vascular resistance was 53.7%, and the increase in cardiac index was 76.9%. All children recovered.
Excerpt from the Treatment of a Patient with Otitis externa artefacta
Authors: G.H. Paar
Journal: Psychotherapy and Psychosomatics (1994)

Case Reports| February 18 2010 Excerpt from the Treatment of a Patient with Otitis externa artefacta Subject Area: Psychiatry and Psychology G.H. Paar G.H. Paar Gelderland-Klinik, Geldern, Deutschland Search for other works by this author on: This Site PubMed Google Scholar Psychother Psychosom (1994) 62 (1-2): 135–139. https://doi.org/10.1159/000288914 Article history Published Online: February 18 2010 Content Tools Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation G.H. Paar; Excerpt from the Treatment of a Patient with Otitis externa artefacta. Psychother Psychosom 31 December 1994; 62 (1-2): 135–139. https://doi.org/10.1159/000288914 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsPsychotherapy and Psychosomatics Search Advanced Search Article PDF first page preview Close Modal 1994Copyright / Drug Dosage / DisclaimerCopyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. You do not currently have access to this content.
Measles immunisation: profit and loss in a general practice.
Authors: G A Binnie
Journal: BMJ (1984)

A survey in one general practice of the occurrence of measles and of immunisation in patients who were born between 1963 and 1982 showed that immunisation not only brought some financial reward to the practice, but by preventing measles reduced the number of consultations related to measles by 40%. Although practice policy often entailed a home visit to immunise a patient, measles disease was three times more likely to require a visit. It is surprising that, considering the efficacy and safety of measles immunisation, in Britain measles has not become the rarity it now is in the United States.
Metabolism of Autologous and Homologous IgG in Rheumatoid Arthritis
Authors: Michael A. Catalano, Edwin H. Krick, David H. De Heer, Robert M. Nakamura, Argyrios N. Theofilopoulos, John H. Vaughan
Journal: Journal of Clinical Investigation (1977)

The metabolism of radioiodinated IgG was studied in 20 patients with rheumatoid arthritis and 11 normal controls using autologous IgG and homologous IgG pooled from normal donors. Fractional catabolic rates in the controls were 4.44% of the autologous- and 4.29% of the homologous-labeled protein per day. The corresponding rates in the rheumatoid patients were 9.67% of the autologous- and 8.64% of the homologous-labeled protein per day. Extravascular catabolism occurred only in the rheumatoid group and accounted essentially for the entire increased catabolism of IgG observed in these patients. 10 patients were especially hypercatabolic, with fractional catabolic rates for autologous IgG greater than 10%. Moreover, they catabolized their autologous IgG significantly faster than the homologous IgG (12.6 vs. 9.9%). The increment of catabolism of autologous over homologous IgG also occurred in the extravascular compartment. These highly hypercatabolic patients had a significantly increased number of manifestations of extra-articular disease.