Acute Infectious Obstructing Bronchiolitis
Authors: JOHN C. HAM
Journal: Annals of Internal Medicine (1964)

Article1 January 1964Acute Infectious Obstructing BronchiolitisA Potentially Fatal Disease in the AdultJOHN C. HAM, M.D., F.A.C.P.JOHN C. HAM, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-60-1-47 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThere has been little published information emphasizing the clinical significance of primary bronchiolitis as a disease process in the adult. In the past few years I have observed several instances of this condition involving significant diagnostic and therapeutic considerations. Before presenting them, some pertinent historical data from the literature will be reviewed.Rubin (1) states that as a clinical entity this condition is rare, as the involvement of the bronchioles is usually part of a bronchopneumonia, but there is no doubt that the condition plays a more important clinical role than is generally suspected. He lists various factors in its...References1. RUBIN EH: Diseases of the Chest, W. B. Saunders Co., Philadelphia, 1947, p. 370. Google Scholar2. NORRISLANDIE WMHR: Diseases of the Chest, 6th Ed. rev., W. B. Saunders Co., Philadelphia, p. 605. Google Scholar3. HOLTMCINTOSH LER: Diseases of Infancy and Childhood, 11th Ed. rev., D. Appleton Century Co., New York, 1940. Google Scholar4. MEAKINS JD: The Practice of Medicine, C. V. Mosley & Co., St. Louis, 1936, pp. 102 and 208. Google Scholar5. WITTIGGEASER HJJ: The relationship between bronchiolitis and childhood asthma. J. Allergy 30: 19, 1959. CrossrefMedlineGoogle Scholar6. PARD LM: The diagnosis of acute bronchiolitis in infants. Amer. J. Roentgen. 45: 41, 1941. Google Scholar7. AUBPITMANBRUESSCHATZKIMALLORYBRICKLEY JCHAMRRBWJ: Management of the Coconut Grove burns at the Massachusetts General Hospital. Ann. Surg. 117: 834, 1943. CrossrefMedlineGoogle Scholar8. FINLANDDAVIDSONLEVENSON MCSSM: Clinical and therapeutic aspects of the conflagration injuries to the respiratory tract sustained by victims of the Coconut Grove disaster. Medicine 25: 215, 1946. CrossrefMedlineGoogle Scholar9. PITTMANSCHATZKI HSR: Pulmonary effects of the Coconut Grove fire. New Eng. J. Med. 241: 1008, 1949. CrossrefMedlineGoogle Scholar10. ENGEL S: Bronchiolitis. Brit. J. Dis. of Chest 53: 125, 1959. CrossrefMedlineGoogle Scholar11. PRATT EL: Acute bronchiolitis in infants. Med. Clin. N. Amer., Sept. 1944, p. 1097. Google Scholar12. MCLEAN KH: The pathology of acute bronchiolitis—a study of its evolution, part I. The exudative phase. Aust. Ann. Med. 5: 254, 1956. MedlineGoogle Scholar13. MCLEAN KH: The pathology of acute bronchiolitis—a study of its evolution, part II. The repair phase. Aust. Ann. Med. 6: 29, 1957. MedlineGoogle Scholar14. PAINESPIERWITEBSKY JRRE: Dornase and antibiotics in pulmonary infections. JAMA 178: 878, 1961. MedlineGoogle Scholar15. UNGERUNGER LAH: Trypsin inhalations in respiratory conditions with thick sputum. JAMA 152: 1109, 1953. CrossrefMedlineGoogle Scholar16. CRAVEN JF: Treatment of obstructing atelectasis by aerosol administration of proteolytic enzymes. J. Pediat. 42: 228, 1953. CrossrefMedlineGoogle Scholar17. CLIFFTON EE: Pancreatic dornase aerosol in pulmonary, endotracheal, and endobronchial disease. Dis. Chest 30: 373, 1956. CrossrefMedlineGoogle Scholar18. CLIFFTONGROSSE EECE: Pancreatic dornase aerosol in postoperative atelectasis. Amer. J. Surg. 100: 447, 1960. CrossrefMedlineGoogle Scholar19. ARMSTRONGWHITE JBJC: Liquifaction of viscous purulent exudate by deoxyribonuclease. Lancet 2: 739, 1950. CrossrefMedlineGoogle Scholar20. SALOMONHERCHFUSSEGAL AJAMD: Aerosols of pancreatic dornase in bronchopulmonary disease. Ann. Allerg. 12: 71, 1954. MedlineGoogle Scholar21. LIMBERREISERRATTIGCURTIS CRHGLCGM: Enzymatic lysis of respiratory secretions by aerosol trypsin. JAMA 149: 816, 1952. CrossrefMedlineGoogle Scholar22. SHERRYJOHNSONTILLETT SAWS: The action of streptococcal desoxyribose nuclease (streptodornase) in vitro and on purulent pleural exudate. J. Clin. Invest. 28, Part 2: 1094, 1949. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: JOHN C. HAM, M.D., F.A.C.P.Affiliations: Providence, Rhode IslandFrom the Thoracic Clinic, Rhode Island Hospital, Providence, Rhode Island.Requests for reprints should be addressed to John C. Ham, M.D., 154 Waterman Street, Providence 6, Rhode Island. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byEtiology and Outcome of Diffuse Acute Infectious Bronchiolitis in AdultsMycoplasma pneumoniae-Associated Bronchiolitis Causing Severe Restrictive Lung Disease in AdultsCryptogenic Organizing Pneumonia A Report of 25 Cases and a Review of the LiteratureWhat are bronchiolitis obliterans organizing pneumonia (BOOP) and cryptogenic organizing pneumonia (COP)?Bronchiolitis obliteransAcute Respiratory Failure: Experiences of a Respiratory Care Unit 1 January 1964Volume 60, Issue 1Page: 47-60KeywordsBacterial physiologyBronchiolesBronchiolitisDyspneaHospitalsHypoxiaInflammationIsoproterenolPneumoniaUpper respiratory tract infections ePublished: 1 December 2008 Issue Published: 1 January 1964 PDF downloadLoading ...