The Gastrointestinal Hormones, Secretin and Cholecystokinin-Pancreozymin
Authors: J. ERIK JORPES
Journal: Annals of Internal Medicine (1961)

Article1 September 1961The Gastrointestinal Hormones, Secretin and Cholecystokinin-PancreozyminJ. ERIK JORPES, M.D., VIKTOR MUTT, M.D.J. ERIK JORPES, M.D.Search for more papers by this author, VIKTOR MUTT, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-55-3-395 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAt the end of my lecture for the Gastroenterology Research Group at the World Congress of Gastroenterology in Washington in May 1958 (1) I drew attention to the length of the period between the observation made by a physiologist that a hormone exists and its introduction as a therapeutic or diagnostic tool in medicine. For insulin it lasted 32 years, for heparin, 20 years. Secretin was discovered in 1902, cholecystokinin in 1928, and pancreozymin in 1943, yet they are not commercially available and consequently are not used to the extent that they deserve to be.The early history of the...References1. JORPESMUTT JEV: Secretin, pancreozymin and cholecystokinin. Gastroenterology 36: 377, 1959. CrossrefMedlineGoogle Scholar2. BABKIN BP: Secretory Mechanism of the Digestive Glands, 2nd Ed., Paul B. Hoeber, Inc., Medical Division of Harper & Brothers, New York, 1950. Google Scholar3. MUTT V: On the preparation of secretin. Arkiv Kemi 15: 75, 1959. Google Scholar4. DREILINGJANOWITZ DAHD: The laboratory diagnosis of pancreatic disease, the secretin test. Amer. J. Gastroent. 28: 268, 1957. MedlineGoogle Scholar5. DREILINGNIEBURGSJANOWITZ DAHEHD: The combined secretin and cytology test in the diagnosis of pancreatic and biliary tract cancer. Med. Clin. N. Amer. 44: 801, 1960. CrossrefMedlineGoogle Scholar6. 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Author, Article, and Disclosure InformationAffiliations: Stockholm, SwedenReceived for publication June 2, 1961.From the Chemistry Department, Karolinska Institutet, Stockholm, Sweden.Presented at the Forty-second Annual Session of The American College of Physicians, Miami Beach, Florida, May 8-12, 1961.Requests for reprints should be addressed to J. Erik Jorpes, M.D., Chemistry Department, Karolinska Institutet, Stockholm, Sweden. 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The Reference StandardCholecystokinin and Pancreozymin, one single Hormone?Pancreozymin-“Augmented” triolein test: A preliminary reportGastrointestinal HormonesAmylase Concentration of Duodenal Aspirates After Stimulation of the Pancreas by a Standard MealPurification of PancreozyminStudies on the Secretin TestProspectus of radiologic technics for gastroenterologyDie Anwendung von Sekretin und Cholecystokinin-Pankreozymin 1 September 1961Volume 55, Issue 3Page: 395-405KeywordsChemical fractionationDiagnostic medicineGastroenterology and hepatologyHeparinHormonesInsulinMucous membranesPancreasProteinsSecretin ePublished: 1 December 2008 Issue Published: 1 September 1961 PDF downloadLoading ...