tbuckley/cabot-search huggingface dataset:
Surgery of the Ambulatory Patient
Authors: William W. Pfaff
Journal: JAMA (1967)

House officers, when they conclude their residencies, have competence to manage the severe or mortal illnesses, but few have the breadth of experience to manage many of the minor ills and injuries that often cause discomfort or disfigurement. In such a void, one may well take counsel in the fourth edition of Dr. Ferguson's well-established text.  With little emphasis on widesweeping principles of surgery, specific courses of therapy are described for specific maladies. The scope of description is sufficiently wide to include the overwhelming majority of surgical problems that can be dealt with in the office or emergency room. Few subjects are dealt with to any great depth, and alternate modes of therapy are noted with brevity. Selection is based on the author's preference, and some forms of treatment will be unfamiliar to younger generations, as in the varied uses of sclerosing solutions.  The book, well and clearly written, is
In Praise of Virtue
Authors: Jack Coulehan
Journal: JAMA (2010)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Evaluation of the role of total paracentesis in management of refractory ascites
Authors: Maged T. El-Ghannam, Naema I. El-Ashry, Ahmed A. El-Ray, Nadia B. Abu Zekri, Gamal A. El-Attar, Magdy M. Youssef, Nadia A. El-Behiry
Journal: Journal of Hepatology (2002)
Psychiatrists as Physicians
Authors: Earle M. Chapman
Journal: JAMA (1967)

<h3>To the Editor:—</h3> Dr. Rogers J. Smith's letter in the<i>AMA News</i>for Jan 9, 1967, was one of many which protested the classification of psychiatrists as an entity separate from physicians in "Doctors Top List in Public Esteem" (<i>News-week</i>, Nov 14, 1966). A mature consideration of possible reasons for this separation, which is lamentable, with subsequent firm action on the part of the entire AMA to heal this breach, is certainly in order. One measure which would help would be for all physicians to conform to the ethical code and respect the rulings of the Judicial Council of the AMA. An editorial, "Professional Courtesy: Our Problem," in<i>American Journal of Psychiatry</i>(<b>123</b>:8 [Feb] 1967) reflects the ruling of the American Psychiatrist Association Committee on Ethics, justifying continuation of fee collection from physicians and their families, which psychiatrists were specifically enjoined not to do in a 1964 ruling of
Sensible guidelines on immunisation.
Authors: D. P. Addy
Journal: BMJ (1989)

We need to be wary of recommending to our colleagues in district general hospitals high tech- nology procedures that are often not available and that require skill.Eighty one years ago James Mackenzie wrote in the preface of his marvellous book3: "In routine practice it is not usually neces- sary to take graphic records.If one-is trained to make careful and minute observations by the ordinary methods, and to have these checked by graphic records, one can ultimately acquire the power of recognising the majority of movements of the circulation without graphic records."Partly out of necessity but also out of kindness to our patients we need to remember his advice.Technology has made possible most of the spectacular advances in cardiology and cardiac surgery in the past 35 years.Once we have learnt from it, however, we can often dispense with it, par- ticularly if we wish to train our successors to be good doctors and not just high technologists.
Disseminated cutaneous epithelioid hemangioma
Authors: Andrew B. Kanik, Chil Hwan Oh, Jag Bhawan
Journal: Journal of the American Academy of Dermatology (1996)

Epithelioid vascular tumors are a heterogeneous group characterized by epithelioid-appearing endothelial cells. Included are benign vascular tumors (epithelioid hemangioma), borderline tumors (epithelioid hemangioendothelioma), and malignant tumors (epithelioid angiosarcoma). We describe a case of multiple epithelioid hemangiomas.
Letter: Rebound hypertension after acute methyldopa withdrawal.
Authors: J N Scott, D G McDevitt
Journal: BMJ (1976)

An experimental technique is described whereby the isolated lung is perfused by means of its respiratory excursion. No perfusion pump is required. Lungs were subjected to positive and negative pressure inflation in a sealed box and were perfused with either blood or blood and low molecular weight dextran at 36° C. and 23°C. In all experiments gross histological changes and pulmonary oedema developed within four hours. Marginally longer perfusions were obtained than in a control series in which a roller pump was used.
Exposures to Air Pollutants during Pregnancy and Preterm Delivery
Authors: Jong-Han Leem, Brian M. Kaplan, Youn K. Shim, Hana R. Pohl, Carol A. Gotway, Stevan M. Bullard, J. Felix Rogers, Melissa M. Smith, Carolyn A. Tylenda
Journal: Environmental Health Perspectives (2006)

The association between preterm delivery (PTD) and exposure to air pollutants has recently become a major concern. We investigated this relationship in Incheon, Republic of Korea, using spatial and temporal modeling to better infer individual exposures. The birth cohort consisted of 52,113 singleton births in 2001–2002, and data included residential address, gestational age, sex, birth date and order, and parental age and education. We used a geographic information system and kriging methods to construct spatial and temporal exposure models. Associations between exposure and PTD were evaluated using univariate and multivariate log-binomial regressions. Given the gestational age, birth date, and the mother's residential address, we estimated each mother's potential exposure to air pollutants during critical periods of the pregnancy. The adjusted risk ratios for PTD in the highest quartiles of the first trimester exposure were 1.26 [95% confidence interval (CI), 1.11–1.44] for carbon monoxide, 1.27 (95% CI, 1.04–1.56) for particulate matter with aerodynamic diameter ≤ 10 μm, 1.24 (95% CI, 1.09–1.41) for nitrogen dioxide, and 1.21 (95% CI, 1.04–1.42) for sulfur dioxide. The relationships between PTD and exposures to CO, NO2, and SO2 were dose dependent (p < 0.001, p < 0.02, p < 0.02, respectively). In addition, the results of our study indicated a significant association between air pollution and PTD during the third trimester of pregnancy. In conclusion, our study showed that relatively low concentrations of air pollution under current air quality standards during pregnancy may contribute to an increased risk of PTD. A biologic mechanism through increased prostaglandin levels that are triggered by inflammatory mediators during exposure periods is discussed.
Trichodysplasia Spinulosa in Gorlin Syndrome Treated With Vismodegib—Reply
Authors: Justin D. Richey, Terrence Katona, Jeffrey B. Travers
Journal: JAMA Dermatology (2014)

hibitors targeting the BRAF V600E mutation exhibited a variety of cutaneous reactions including spiny follicular papules. 4,5 Given the similarity of findings in patients taking these smallmolecule drugs (namely vemurafenib, sorafenib, and vismodegib), spiny hyperkeratosis could be the suggested term for this adverse effect and may represent a distinct entity.The term trichodysplasia spinulosa should be reserved for immunocompromised individuals with proven TSPyV infection.
The Paradox of Beta-Adrenergic Blockade in Hypertension
Authors: EDWARD D. FROHLICH, ROBERT C. TARAZI, HARRIET P. DUSTAN, IRVINE H. PAGE
Journal: Circulation (1968)

The effects of long-term treatment with propranolol, a beta-adrenergic blocking drug, were determined in 19 hypertensive patients (five with renal arterial disease, two with renal parenchymal disease, and 12 with essential hypertension) whose vascular disease was of mild to moderate severity. The drug reduced arterial pressure in 16 patients during 32 weeks of treatment (average); daily dose was 180 mg (average). No side effects required discontinuance of treatment. Orthostatic hypotension did not occur, an unusual finding for an antihypertensive drug which acts to inhibit autonomic neural function. In seven patients, hemodynamic studies, performed during treatment (after 10 months, average), confirmed reduction of arterial pressure and heart rate, and demonstrated associated diminution of cardiac output and increased peripheral resistance.
Reviews and Notes: Legal Medicine: Medical Malpractice and the American Jury: Confronting the Myths about Jury Incompetence, Deep Pockets, and Outrageous Damage Awards
Authors: Angela R. Holder
Journal: Annals of Internal Medicine (1996)

Literature of Medicine1 May 1996Reviews and Notes: Legal Medicine: Medical Malpractice and the American Jury: Confronting the Myths about Jury Incompetence, Deep Pockets, and Outrageous Damage AwardsAngela R. Holder, LLMAngela R. Holder, LLMYale University School of Medicine New Haven, CT 06510Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-124-9-199605010-00020 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail N Vidmar. 318 pages. Ann Arbor: Univ of Michigan Pr; 1995. $34.50. ISBN 0-472-10639-2. Order phone 313-764-4388.Are juries sufficiently sensible to make rational decisions in malpractice and other sorts of personal injury cases? Many scholars believe that malpractice cases should be decided by expert arbitrators because lay people can't understand complex medical issues.Professor Vidmar begs to differ. In an exhaustive study of malpractice cases in North Carolina (part of an even larger study of malpractice litigation that has been undertaken by Duke University), he gives fascinating descriptions of the facts of malpractice cases as they are litigated. He ... Author, Article, and Disclosure InformationAffiliations: Yale University School of Medicine New Haven, CT 06510 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 May 1996Volume 124, Issue 9Page: 857-858KeywordsStatistical data ePublished: 15 August 2000 Issue Published: 1 May 1996 Copyright & PermissionsCopyright © 1996 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Reviews and Notes: Final Passages: Positive Choices for the Dying and Their Loved Ones
Authors: Arthur W. Feinberg
Journal: Annals of Internal Medicine (1994)

Literature of Medicine1 February 1994Reviews and Notes: Final Passages: Positive Choices for the Dying and Their Loved OnesArthur W. FeinbergArthur W. FeinbergNorth Shore University Hospital, Manhasset, NY 11030Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-120-3-199402010-00028 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Final Passages: Positive Choices for the Dying and Their Loved OnesJudith Ahronheim and Doron Weber. 285 pages. New York: Simon & Schuster; 1992. $18.00.Concurrent with the marked upsurge in the availability and sophistication of medical technology, public concentration on and discussion of the way Americans die has also increased. All aspects of the dying process are being scrutinized, and an active debate has started on such profound issues as the cost, both in dollars and resources, of providing medical care to the terminally ill, the use of machines to prolong the dying process, and the ethical issues involved ... Author, Article, and Disclosure InformationAffiliations: North Shore University Hospital, Manhasset, NY 11030 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 February 1994Volume 120, Issue 3Page: 252KeywordsAttentionEuthanasiaForecastingGeriatricsIntensive care unitsSuicide ePublished: 15 August 2000 Issue Published: 1 February 1994 Copyright & PermissionsCopyright © 1994 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Myocardial Oxygen Metabolism and Myocardial Blood Flow in Dogs in Hemorrhagic Shock
Authors: NORMAN B. RATLIFF, DONALD B. HACKEL, EILEEN MIKAT
Journal: Circulation Research (1969)

We have studied the interrelations of myocardial oxygen metabolism and myocardial blood flow in hemorrhagic shock. Myocardial blood flow was measured by the 133 Xe-washout method in closed-chest anesthetized dogs while the dogs were breathing either room air at ambient pressure or oxygen at high pressure. In animals with normal blood pressure, oxygen at high pressure produced a consistent decrease in myocardial blood flow from a mean of 70 ml/100 g/min to a mean of 43 ml/100 g/min, with a proportionate decrease in myocardial O 2 consumption. In animals in hemorrhagic shock, oxygen at high pressure induced no change in myocardial blood flow but increased myocardial O 2 consumption from a mean of 5.9 ml/100 g/min to a mean of 7.4 ml/100 g/min. When the animals in hemorrhagic shock breathed room air again at ambient pressure following oxygen at high pressure, the myocardial blood flow increased from a mean of 40 ml/100 g/min to a mean of 51 ml/100 g/min. The myocardial O 2 consumption did not change. We conclude that with decreasing blood pressure a baseline of myocardial blood flow may be reached, so that a further decrease no longer occurs in response to hyperoxia. However, the control of myocardial blood flow in shock is an active process responsive to complex positive control mechanisms that may be altered and studied experimentally.
Cytocompatibility, osseointegration, and bioactivity of three-dimensional porous and nanostructured network on polyetheretherketone
Authors: Ying Zhao, Hoi Man Wong, Wenhao Wang, Penghui Li, Zushun Xu, Eva Y.W. Chong, Chun Hoi Yan, Kelvin W.K. Yeung, Paul K. Chu
Journal: Biomaterials (2013)
Bloody but unbowed
Authors: I. Robertson
Journal: BMJ (1996)

A woman phones the Invermacsnaid Advertiser.

“Is that the classified advertisements?”

“Yes madam.”

“I want to put in a death notice. How much is it a word?”

“Two pounds.”

“Fine. Here's my advert: ‘McKay's dead.’”

“Sorry, madam, a death notice has to be minimum of five words.”

Long pause.

“Very well, then, make it this: ‘McKay's dead. Volvo for sale.’”

I was recently at a conference (at the Royal College of Physicians) jointly sponsored by the Medical Research Council and Unilever on the psychology of mood and wellbeing. Both organisations have an interest in making us happy, it seems, but the elusive nature of (excuse me while …
Metabolism of cholesterol-rich chylomicroms. Mechanism of binding and uptake of cholesteryl esters by the vascular bed of the perfused rat heart.
Authors: C J Fielding
Journal: Journal of Clinical Investigation (1978)

The rate of uptake of cholesteryl ester from chylomicrons has been determined with the isolated perfused rat heart and both intact and functionally hepatectomized rats. Uptake was found to be proportional to the cholesteryl ester content of the particles. Transfer of cholesteryl ester to other lipoprotein classes of the plasma was negligible under these conditions, and loss of cholesteryl ester from the medium was associated with quantitative recovery in the vascular bed. The uptake mechanism was nonsaturable and independent of the lipoprotein lipase binding site. Compared with receptor-dependent uptake of low density lipoprotein cholesteryl ester by heart endothelium, the chylomicron pathway appears to provide a major proportion of cholesteryl ester cleared from the plasma. Uptake was initially heparin dependent, and cleared lipid was released by 10 microgram/ml of heparin; however, lipid taken up rapidly became heparin resistant and was then hydrolyzed slowly with production of unesterified fatty acid. These results are discussed in the context of the possible role of cholesterol-rich chylomicron remnant lipoproteins in atherogenesis.
In Vivo 18F-Fluorodeoxyglucose Positron Emission Tomography Imaging Provides a Noninvasive Measure of Carotid Plaque Inflammation in Patients
Authors: Ahmed Tawakol, Raymond Q. Migrino, Gregory G. Bashian, Shahinaz Bedri, David Vermylen, Ricardo C. Cury, Denise Yates, Glenn M. LaMuraglia, Karen Furie, Stuart Houser, Henry Gewirtz, James E. Muller, Thomas J. Brady, Alan J. Fischman
Journal: Journal of the American College of Cardiology (2006)
Dexpanthenol in Postoperative Ileus
Authors: Alvin L. Watne
Journal: JAMA (1963)

<h3>To the Editor:</h3> —In reply to your question concerning the definition of the term "ridit" as used in our recent article on "The Role of Dexpanthenol in Postoperative Ileus," Dr. Irwin Bross and Miss Barbara Ann Cote of our statistical department have provided the following explanation: The ridit for "day of onset of bowel sounds" has the following meaning. The frequency distribution of "day of onset of bowel sounds" in the control (saline placebo) series is taken as the reference or "identified" distribution. In this study the later the onset, the less favorable the situation. The ridit for onset on day 3 (see Fig 4) is roughly 0.75. This numerical value was attained by adding the proportion of control patients with onset on day 1 and day 2 and half of the corresponding patients on day 3 (this is the<i>operational</i>definition of the ridit here). In other words, an
THE UNLOCKING OF WARDS IN MENTAL HOSPITALS
Authors: L. C. HURST
Journal: American Journal of Psychiatry (1957)

Consideration is given to the problems raised by the unlocking of the chronic wards in mental hospitals. The deteriorated schizophrenic, who has spent many years in the hospital, provides most of the difficulties. Attempts to employ this type of patient in small groups of 10 to 18 have produced good results(7, 6) and afford adequate supervision, The need for, and difficulties of, objective assessment of the effects of ward opening are emphasised.
Dynamic behavior of lymphocyte subgroups correlates with clinical outcomes in human H7N9 infection
Authors: Yu Chen, Xuefen Li, Li Tian, Shufa Zheng, Shigui Yang, Yuejiao Dong, Yiyin Wang, Dawei Cui, Xiaoli Liu, Weifeng Liang, Honglin Chen, Lanjuan Li
Journal: Journal of Infection (2014)
Methylenetetrahydrofolate Reductase Gene and Coronary Artery Disease
Authors: Frank M. van Bockxmeer, Cyril D.S. Mamotte, Samuel D. Vasikaran, Roger R. Taylor
Journal: Circulation (1997)

Background Hyperhomocysteinemia has been substantiated as a risk factor for occlusive vascular disease. A common mutation (nucleotide 677 C→T) has been described recently in the 5,10-methylenetetrahydrofolate reductase ( MTHFR ) gene, which results in a valine for alanine substitution, a thermolabile enzyme, and a tendency to elevate plasma homocysteine levels and which has been proposed to contribute importantly to coronary artery disease. Methods and Results To study the potential influence of the mutation on ischemic heart disease, we screened 555 whites with angiographically documented coronary artery disease and 143 unrelated control subjects without a history of angina or myocardial infarction randomly selected from the community. The patients were in two groups: group 1 comprised 358 prospectively recruited individuals younger than 50 years, and group 2, 197 patients investigated prospectively for restenosis 6 months after coronary angioplasty. The frequency of homozygosity for the mutation was 10.5% in control subjects, 10.6% in group 1, and 9.1% in group 2 patients. There was no relationship between MTHFR genotype and number of coronary vessels with &gt;50% diameter obstruction, prior myocardial infarction, or restenosis after coronary angioplasty. Plasma folate concentrations in control subjects (n=90) and patients (n=208) showed closely similar distributions. Conclusions Although it is accepted that moderate hyperhomocysteinemia significantly increases the risk for coronary, cerebrovascular, and peripheral vascular diseases, our data suggest that a mutation of the MTHFR gene, which has been associated with a thermolabile form of the enzyme and with hyperhomocysteinemia in subjects with plasma folate below the median, does not appear to be significantly associated with risk for premature coronary artery disease or for restenosis after coronary angioplasty.
The induction of bone formation in rat calvarial defects and subcutaneous tissues by recombinant human BMP-2, produced in Escherichia coli
Authors: Ji-Hyun Lee, Chang-Sung Kim, Kyung-Hee Choi, Ui-Won Jung, Jeong-Ho Yun, Seong-Ho Choi, Kyoo-Sung Cho
Journal: Biomaterials (2010)
What can we expect from models of motor control?
Authors: Gerald E. Loeb
Journal: Behavioral and Brain Sciences (1995)

Abstract The lambda model of servocontrol seems superior to the alpha model in terms of dealing with the mechanical complexities of nonlinear and multiarticular muscles. Both, however, can be trivialized by noting that the “control variable” may simply be the sum of descending influences at propriospinal interneurons in the case of the lambda model or in the muscles themselves in the case of the alpha model. The notion that the brain explicitly computes output in terms of any such control variables may be an engineering metaphor, useful for conceptual understanding but not for generating predictive hypotheses about higher motor circuitry.
EARLY ???REDISTRIBUTION??? OF SESTAMIBI: A COMPARISON OF SPECT IMAGING 15 MINUTES AND ONE HOUR AFTER DIPYRIDAMOLE STRESS
Authors: Arnold J. Pollak, Ismael Mena, Javier Villanueva-Meyer, Kenneth A. Narahara
Journal: Clinical Nuclear Medicine (1993)

Pollak, Arnold J.; Mena, Ismael; Villanueva-Meyer, Javier; Narahara, Kenneth A. Author Information
Book Review Pain in Infants, Children, and Adolescents Second edition. Edited by Neil L. Schechter, Charles B. Berde, and Myron Yaster. 892 pp., illustrated. Philadelphia, Lippincott Williams &amp; Wilkins, 2003. $145. 0-7817-2644-1
Authors: John M. Goddard
Journal: New England Journal of Medicine (2003)