Splenic Infarction after Cocaine Use
Authors: Karen D. Novielli, Christopher V. Chambers
Journal: Annals of Internal Medicine (1991)

Letters1 February 1991Splenic Infarction after Cocaine UseKaren D. Novielli, MD, Christopher V. Chambers, MDKaren D. Novielli, MDSearch for more papers by this author, Christopher V. Chambers, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-114-3-251 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editors: Cocaine has been implicated in ischemic injury to multiple organ systems. We report a case of splenic infarction temporally related to cocaine use.A 38-year-old black woman presented to the emergency department with 2 days of left upper quadrant abdominal pain, nausea, and intractable vomiting. She reported having used intravenous cocaine, pentazocine, and methylphenidate a few hours before the onset of symptoms. She also had interstitial lung disease with pulmonary hypertension. She denied recent air travel or exposure to high altitudes. Except for a temperature of 37.6 °C and left upper quadrant abdominal tenderness, findings from the...References1. Creglar L and Mark H. Medical complications of cocaine abuse. N Engl J Med. 1986;315:1495-500. CrossrefMedlineGoogle Scholar2. Mathias D. Cocaine-associated myocardial ischemia. Am J Med. 1986;81:675-8. CrossrefMedlineGoogle Scholar3. Poklis A, Maginn D, and Barr J. Tissue disposition of cocaine in man: a report of five fatal poisonings. Forensic Sci Int. 1987;33:83-8. CrossrefMedlineGoogle Scholar4. Githen J, Gross G, Eife R, and Wallner S. Splenic sequestration syndrome at mountain altitudes in sickle/hemoglobin C disease. J Pediatr. 1977;90:203-6. CrossrefMedlineGoogle Scholar5. Conn H. Sickle-cell trait and splenic infarction associated with high-altitude flying. N Engl J Med. 1954;251:417-20. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: Karen D. Novielli, MD; Christopher V. Chambers, MDAffiliations: Thomas Jefferson University Hospital Philadelphia, PA 19107 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byIschemic Stroke in a Young Man BodybuilderSplenic infarction in sickle cell trait: A comprehensive systematic review of case studiesAtraumatic splenic rupture in young adult following cocaine useHistopathology and Drug AbuseCocaineCocaine Use and Splenic Rupture: A Rare Yet Serious AssociationCocaineSplenic infarction associated with sickle cell trait at low altitudeAtraumatic splenic rupture and ileal volvulus following cocaine abuseSurgical Challenges associated with the use of Illicit Street DrugsHistopathology and Drug AbuseHeroin-associated myocardial damages—Conventional and immunohistochemical investigationsInfarto esplénico asociado a cocaína y úlcera gástrica por tuberculosisFour-Extremity Gangrene Associated With Crack Cocaine AbuseCocaïneCocaine-associated abscesses with lethal sepsis after splenic infarction in an 17-year-old womanCocaineSplenic Hematoma in Hb S-?+thalassemiaCocaine-associated myocardial and mesenteric ischemia: A case report and review of the literatureCocaine administration induces human splenic constriction and altered hematologic parametersThrombotic thrombocytopenic purpura in pregnancyLegal aspects of venepunctureSplenic infarction related to cocaine useCocaine-induced multiple vascular occlusionsA Placebo-Controlled Elimination Study to Identify Potential Treatment Agents for Cocaine DetoxificationOverview: Diagnosis of Hepatitis C Virus Infection using Synthetic PeptidesImproved detection of hepatitis c virus antibodies in high-risk populationsDrugs of abuse 1 February 1991Volume 114, Issue 3 Page: 251-252 Keywords Abdominal pain Cocaine Emergency department Infarction Interstitial lung diseases Nausea Pulmonary hypertension Temperature Vomiting ePublished: 1 December 2008 Issue Published: 1 February 1991 PDF downloadLoading ...