Congestive Cardiomyopathy and Illness Related to the Acquired Immunodeficiency Syndrome (AIDS) Associated with Isolation of Retrovirus from Myocardium
Authors: LEONARD H. CALABRESE
Journal: Annals of Internal Medicine (1987)

Brief Reports1 November 1987Congestive Cardiomyopathy and Illness Related to the Acquired Immunodeficiency Syndrome (AIDS) Associated with Isolation of Retrovirus from MyocardiumLEONARD H. CALABRESE, D.O., MAX R. PROFFITT, Ph.D., BELINDA YEN-LIEBERMAN, Ph.D., ROBERT E. HOBBS, M.D., NORMAN B. RATLIFF, M.D.LEONARD H. CALABRESE, D.O., MAX R. PROFFITT, Ph.D., BELINDA YEN-LIEBERMAN, Ph.D., ROBERT E. HOBBS, M.D., NORMAN B. RATLIFF, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-107-5-691 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptMost clinical signs and symptoms reported in persons infected with the human immunodeficiency virus (HIV) are due to opportunistic infections or malignancies that flourish in the presence of profound immunosuppression. Some important clinical findings, however, involving the gastrointestinal, hematologic, and central nervous systems are not readily explainable on this basis and have raised the possibility of an alternative pathogenic mechanism such as a direct effect from the virus itself. Cardiac manifestations in patients with the acquired immunodeficiency syndrome (AIDS) have not been frequently reported, but have generally reflected opportunistic infections of the myocardium itself (1, 2) or direct involvement with...References1. HENOCHOWICZ S, MUSTAFA M, LAWRINSON W, PISTOLE M, and LINDSAY J. Cardiac aspergillosis in acquired immune deficiency syndrome. Am J Cardiol. 1985;5:1239-40. CrossrefGoogle Scholar2. CAMMAROSANO C and LEWIS W. Cardiac lesions in acquired immune deficiency syndrome (AIDS). J Am Coll Cardiol. 1985;5:703-6. CrossrefMedlineGoogle Scholar3. COHEN I, ANDERSON I, and VIRMANI R. Congestive cardiomyopathy in association with the acquired immunodeficiency syndrome. N Engl J Med. 1986;315:628-30. CrossrefMedlineGoogle Scholar4. ANDERSON R, VIRMANI R, O'LEARY T, ROBINOWITZ M, MACKER A, and ROBERTS W. Dilitated cardiomyopathy and myocarditis in the acquired immune deficiency syndrome [Abstract]. Circulation. 1986;74:11-142. Google Scholar5. POPOVIC M, SARNGADHARAN M, READ E, and GALLO R. Detection, isolation and continuous production of cytopathic retroviruses (HTLVIII) from patients with AIDS and pre-AIDS. Science. 1984;224:497-500. CrossrefMedlineGoogle Scholar6. MCDOUGAL J, CORT S, and KENNEDY M. Immunoassay for the detection and quantitation of infectious human retrovirus, lymphadenopathy-associated virus (LAV). J Immunol Methods. 1985;76:171-83. CrossrefMedlineGoogle Scholar7. KOENIG S, GENDELMAN H, and ORENSTEIN J. Detection of AIDS virus in macrophages in brain tissue from AIDS patients with encephalopathy. Science. 1986;233:1089-93. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: LEONARD H. CALABRESE, D.O.; MAX R. PROFFITT, Ph.D.; BELINDA YEN-LIEBERMAN, Ph.D.; ROBERT E. HOBBS, M.D.; NORMAN B. RATLIFF, M.D.Affiliations: Cleveland Clinic Foundation Cleveland, Ohio PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byImmune Dysregulation in Myocardial Fibrosis, Steatosis, and Heart Failure: Current Insights from HIV and the General PopulationHeart Failure among People with HIV: Evolving Risks, Mechanisms, and Preventive ConsiderationsMyocarditis and PericarditisHIV and Nonischemic Heart DiseaseThe physical and psychological effects of HIV infection and its treatment on perinatally HIV-infected childrenGetting to 90-90-90 in paediatric HIV: What is needed?Human Immunodeficiency Virus and Heart Failure in Low- and Middle-Income CountriesMyocarditis and PericarditisBiopsy-proven autoimmune myocarditis in HIV-associated dilated cardiomyopathyRelationships Among HIV Infection, Metabolic Risk Factors, and Left Ventricular Structure and FunctionThe impact of HAART on cardiomyopathy among children and adolescents perinatally infected with HIV-1Impact of Highly Active Antiretroviral Therapy on paediatric Human Immunodeficiency Virus-associated left ventricular dysfunction within the Johannesburg teaching hospital complexMyocarditis and pericarditisMyocarditis and PericarditisP38 MAP Kinase Inhibitor Prevents Diastolic Dysfunction in Rats Following HIV gp120 Injection In vivoDilated Cardiomyopathy in Transgenic Mice Expressing HIV TatLeft Ventricular Dysfunction in Human Immunodeficiency Virus InfectionMyocardial disease in human immunodeficiency virus (HIV) infection: a reviewCardiovascular Involvement in Acquired Immune Deficiency SyndromeAerobic Exercise Dysfunction in Human Immunodeficiency Virus: A Potential Link to Physical DisabilityRight and left ventricular cardiac function in a developed world population with human immunodeficiency virus studied with radionuclide ventriculographyCardiac Manifestations in Human Immunodeficiency Virus InfectionImpaired oxygen on-kinetics in persons with human immunodeficiency virus are not due to highly active antiretroviral therapy11No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit upon the author(s) or upon any organization with which the author(s) is/are associated.Decreased peak arteriovenous oxygen difference during treadmill exercise testing in individuals infected with the human immunodeficiency virus11No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit upon the author(s) or upon any organization with which the author(s) is/are associated.Cocaine Increases Mortality and Cardiac Mass in a Murine Transgenic Model of Acquired Immune Deficiency SyndromeCardiac Tamponade in Patients with Human Immunodeficiency Virus DiseaseImmunopathogenesis of HIV-related heart muscle diseaseHIV and direct damage of organsOverview on the incidence and the characteristics of HIV-related opportunistic infections and neoplasms of the heartEchocardiography in HIV cardiac diseaseAcute Coronary Syndrome in Patients with Human Immunodeficiency Virus DiseaseCan cocaine abuse exacerbate the cardiac toxicity of human immunodeficiency virus?Alteraciones cardíacas en el paciente con infección crónica por el virus de la inmunodeficiencia humana tipo 1Cardiomyopathy in AIDS: A pathophysiological perspectiveCocaine Injection and Coxsackievirus B3 Infection Increase Heart Disease During Murine AIDSCocaine Injection and Coxsackievirus B3 Infection Increase Heart Disease During Murine AIDSAutonomic neuropathy in patients with HIV: Course, impact of disease stage, and medicationCardiac Dysfunction Occurs in the HIV-1 Transgenic Mouse Treated with ZidovudineDilatative Kardiomyopathie (DCM) Morphologie und Ätiologie. Myokarditis und DCMHuman Immunodeficiency VirusesThe detection of viral genomes by polymerase chain reaction in the myocardium of pediatric patients with advanced HIV diseaseIncidence of Dilated Cardiomyopathy and Detection of HIV in Myocardial Cells of HIV-Positive PatientsCardiac Involvement in the Acquired Immunodeficiency Syndrome: A Multicenter Clinical-Pathological StudyCardiac involvement in acquired immunodeficiency syndrome-a review to push actionCardiac Manifestations of HIV/AIDSLeft ventricular dysfunction in human immunodeficiency virus (HIV)-infected patientsHuman immunodeficiency virus infection after heart transplantation: Development of cardiomyopathy after long-term survivalCardiac pathology of pediatric HIV infectionAfectación cardíaca en el sidaCARDIAC INVOLVEMENT IN HIV INFECTIONEarly Impairment of Systolic and Diastolic Function in Asymptomatic HIV-Positive Patients: A Multicenter Echocardiographic and Echo–Doppler StudyLong-term cardiac follow-up of children with perinatally acquired human immunodeficiency virus-type 1 infectionPericardial Effusion in AIDSMyocardial atrophy in acquired immunodeficiency syndrome—associated wastingAIDS and the heart: Clinicopathologic assessmentLeft ventricular segmental wall motion abnormality in septic shockOvine aortic smooth muscle cells allow the replication of visna-maedi virus in vitroFrequency of development of acute global left ventricular dysfunction in human immunodeficiency virus infectionMycarditis and cardiotropic viral infection associated with severe left ventricular dysfunction in late-stage infection with human immunodeficiency virusElectrolyte and acid-base disorders associated with AIDSHuman immunodeficiency virus infection and systolic myocardial performanceScreening for Pathogenic DNA Sequences in Clinically Collected Human TissuesPathology of Pediatric AIDS: Overview, Update, and Future DirectionCardiac Tamponade in Patients Infected with HIVCase 34-1993Postoperative Complications in Patients With Human Immunodeficiency Virus DiseasePrevalence and incidence of left ventricular dysfunction in patients with human immunodeficiency virus infectionMyocardial dysfunction in patients infected with HIV: prevalence and risk factorsCase 44-1992Dilated cardiomyopathy in a zidovudine-treated AIDS patientDilated cardiomyopathies of childhoodAIDS and the heart: Review and consideration of pathogenetic mechanismsCardiac myocytes and dendritic cells harbor human immunodeficiency virus in infected patients with and without cardiac dysfunction: Detection by multiplex, nested, polymerase chain reaction in individually microdissected cells from right ventricular endomyocardial biopsy tissueCardiac manifestations of acquired immune deficiency syndrome: A 1991 updateSpontaneous Regression of Cardiomyopathy in a Patient with the Acquired Immunodeficiency Syndrome*Medical Care of the HIV-Infected ChildAnesthetic Management of AIDS PatientsViral and Cellular Factors Influencing HIV TropismDilated cardiomyopathy and eriterovirusesCardiac involvement in aidsInfection of the heart by the human immunodeficiency virusIdentification of human immunodeficiency virus-1 RNA and DNA in the heart of a child with cardiovascular abnormalities and congenital acquired immune deficiency syndromeViral Heart DiseaseEmerging patterns of heart disease in human immunodeficiency virus infectionPulmonary Consequences of Congenital and Acquired Primary Immunodeficiency StatesReversible Cardiac Dysfunction Associated with Interferon Alfa Therapy in AIDS Patients with Kaposi's SarcomaAIDS: Cardiac findings from 115 autopsiesUnsuspected Cardiac Abnormalities in the Acquired Immune Deficiency SyndromeCardiovascular manifestations of human immunodeficiency virus infection in infants and childrenAcquired immunodeficiency syndrome and heart disease: The present and the futureThe challenge of cardiomyopathyCardiac manifestations of human immunodeficiency virus infection: A two-dimensional echocardiographic studyAcquired immune deficiency syndrome: The heart of the matterCardiac complications in acquired immunodeficiency syndrome (AIDS): A reviewCardiac involvement in the acquired immune deficiency syndromeComparison among acquired immune deficiency syndrome patients with and without clinical evidence of cardiac diseaseCardiac Findings in AIDSAIDS AND THE HEARTMyocarditis diagnosed by endpmyocardial biopsy in human immunodeficiency virus infection with cardiac dysfunctionThe Dilated Cardiomyopathies: Clinical AspectsHuman Immunodeficiency Virus, Coxsackievirus, and CardiomyopathyHOWARD DITTRICH, M.D., LEON CHOW, M.D., FRANK DENARO, Ph.D., STEPHEN SPECTOR, M.D.Die Klinik von AIDS — opportunistische Infektionen von Lunge und Herz 1 November 1987Volume 107, Issue 5Page: 691-692KeywordsAIDSClinical immunologyDilated cardiomyopathyHIVHeart diseasesMyocardiumOpportunistic infectionsPathogensRetrovirusesSigns and symptoms ePublished: 1 December 2008 Issue Published: 1 November 1987 PDF downloadLoading ...