Optimal Prediction of Diabetes
Authors: Greg Bombassei
Journal: Annals of Internal Medicine (2002)

Letters19 November 2002Optimal Prediction of DiabetesGreg Bombassei, MDGreg Bombassei, MDDanbury Hospital; Danbury, CT 06810 (Bombassei)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-137-10-200211190-00019 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Recent studies demonstrate that it is possible to delay or prevent type 2 diabetes mellitus in persons at high risk for the disease. Proven strategies include weight loss (1-3) through diet and exercise (2, 3) or treatment with metformin (3), or treatment with troglitazone (4), which is no longer commercially available. It is important to identify persons at high risk for type 2 diabetes mellitus.At issue is how best to identify these at-risk persons. Stern and colleagues (5) advance a “simplified [clinical] model” to estimate a person's risk and contend that it is preferable to performing ...References1. Hu FB, Manson JE, Stampfer MJ, Colditz G, Liu S, Solomon CG, et al. . Diet, lifestyle, and the risk of type 2 diabetes mellitus in women. N Engl J Med. 2001;345:790-7. [PMID: 11556298] CrossrefMedlineGoogle Scholar2. Tuomilehto J, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, Ilanne-Parikka P, et al. . Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med. 2001;344:1343-50. [PMID: 11333990] CrossrefMedlineGoogle Scholar3. Knowler WC, Barrett-Connor E, Fowler SE, Hamman RF, Lachin JM, Walker EA, et al. . Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med. 2002;346:393-403. [PMID: 11832527] CrossrefMedlineGoogle Scholar4. Buchanan TA, Xiang AH, Peters RK, Kjos SL, Marroquin A, Goico J, et al. . Preservation of pancreatic β-cell function and prevention of type 2 diabetes by pharmacological treatment of insulin resistance in high-risk hispanic women. Diabetes. 2002;51:2796-803. [PMID: 12196473] CrossrefMedlineGoogle Scholar5. Stern MP, Williams K, Haffner SM. Identification of persons at high risk for type 2 diabetes mellitus: do we need the oral glucose tolerance test? Ann Intern Med. 2002;136:575-81. [PMID: 11955025] LinkGoogle Scholar Author, Article, and Disclosure InformationAuthors: Greg Bombassei, MDAffiliations: Danbury Hospital; Danbury, CT 06810 (Bombassei) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoIdentification of Persons at High Risk for Type 2 Diabetes Mellitus: Do We Need the Oral Glucose Tolerance Test? Michael P. Stern , Ken Williams , and Steven M. Haffner Optimal Prediction of Diabetes Michael P. Stern , Ken Williams , and Steven M. Haffner Metrics 19 November 2002Volume 137, Issue 10Page: 856KeywordsBlood plasmaDietExerciseGlucoseOral glucose tolerance testPersonal computersType 2 diabetesWeight loss ePublished: 19 November 2002 Issue Published: 19 November 2002 Copyright & PermissionsCopyright © 2002 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...