Ultrasonography to Guide Duration of Anticoagulation in DVT
Authors: Jongoh Kim
Journal: Annals of Internal Medicine (2009)

Letters1 December 2009Ultrasonography to Guide Duration of Anticoagulation in DVTJongoh Kim, MDJongoh Kim, MDFrom Albert Einstein Medical Center, Philadelphia, PA 19141.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-151-11-200912010-00024 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Prandoni and colleagues (1) showed that basing the duration of anticoagulation on ultrasonography findings can lead to better outcomes. However, the study participants had surprisingly high rates of residual thrombus after completing the recommended duration of anticoagulation: 29.4% of participants who received fixed oral anticoagulant therapy had residual thrombus, and 53.0% of participants who received flexible oral anticoagulant therapy were given treatment longer than recommended because of nonrecanalization. In comparison, in a recent study (2), treatment failed in 1.6% and 2.6% of the participants who received anticoagulation for 3 and 6 months, respectively. Residual thrombus after treatment ...References1. Prandoni P, Prins MH, Lensing AW, Ghirarduzzi A, Ageno W, Imberti D, et al; AESOPUS Investigators. Residual thrombosis on ultrasonography to guide the duration of anticoagulation in patients with deep venous thrombosis: a randomized trial. Ann Intern Med. 2009;150:577-85. [PMID: 19414836] LinkGoogle Scholar2. Campbell IA, Bentley DP, Prescott RJ, Routledge PA, Shetty HG, Williamson IJ. Anticoagulation for three versus six months in patients with deep vein thrombosis or pulmonary embolism, or both: randomised trial. BMJ. 2007;334:674. [PMID: 17289685] CrossrefMedlineGoogle Scholar3. Young L, Ockelford P, Milne D, Rolfe-Vyson V, Mckelvie S, Harper P. Post-treatment residual thrombus increases the risk of recurrent deep vein thrombosis and mortality. J Thromb Haemost. 2006;4:1919-24. [PMID: 16836658] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Albert Einstein Medical Center, Philadelphia, PA 19141.Disclosures: None disclosed. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoResidual Thrombosis on Ultrasonography to Guide the Duration of Anticoagulation in Patients With Deep Venous Thrombosis Paolo Prandoni , Martin H. Prins , Anthonie W.A. Lensing , Angelo Ghirarduzzi , Walter Ageno , Davide Imberti , Gianluigi Scannapieco , Giovanni B. Ambrosio , Raffaele Pesavento , Stefano Cuppini , Roberto Quintavalla , Giancarlo Agnelli , and Ultrasonography to Guide Duration of Anticoagulation in DVT Stephan Imfeld , Daniel Staub , Heiko Uthoff , Thomas Baldi , Markus Aschwanden , and Kurt A. Jaeger Ultrasonography to Guide Duration of Anticoagulation in DVT Paolo Prandoni , Anthonie W.A. Lensing , and Martin H. Prins Metrics 1 December 2009Volume 151, Issue 11Page: 825-826KeywordsAnticoagulant therapyConflicts of interestDeep vein thrombosisMedical risk factorsThrombosisUltrasound imaging ePublished: 1 December 2009 Issue Published: 1 December 2009 CopyrightCopyright © 2009 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...