The Fever of Sarcoidosis
Authors: JAMES P. NOLAN
Journal: Annals of Internal Medicine (1964)

Article1 September 1964The Fever of SarcoidosisJAMES P. NOLAN, M.D., GERALD KLATSKIN, M.D., F.A.C.P.JAMES P. NOLAN, M.D., GERALD KLATSKIN, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-61-3-455 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptJudging from the literature, it would appear that fever is not a significant feature of sarcoidosis except in cases with erythema nodosum or uveoparotitis. Indeed, no mention is made of this symptom in two comprehensive reviews of the subject (1, 2), and in most other reports, while fever is listed as one manifestation of the disease in from 3 to 28% of cases, the authors either omit any comment or imply that it is low grade in character (3-9). Only a few authors have pointed out that the fever may attain high levels or persist for long periods of time...References1. FREIMAN DG: Sarcoidosis. New Eng. J. Med. 239: 664-669, 709-716, 743-749, 1948. CrossrefMedlineGoogle Scholar2. JAMES DG: Diagnosis and treatment of sarcoidosis. Brit. Med. J. 2: 900-904, 1956. CrossrefMedlineGoogle Scholar3. LONGCOPEFREIMAN WTDG: A study of sarcoidosis based on a combined investigation of 160 cases including 30 autopsies from the Johns Hopkins Hospital and Massachusetts General Hospital. Medicine (Balt.) 31: 1-89, 1952. CrossrefMedlineGoogle Scholar4. RICKERCLARK WM: Sarcoidosis: a clinicopathologic review of three hundred cases including twenty-two autopsies. Amer. J. Clin. Path. 19: 725-749, 1949. CrossrefMedlineGoogle Scholar5. ISRAELSONES HLM: Sarcoidosis: clinical observations on one hundred sixty cases. Arch. Intern. Med. (Chicago) 102: 766-776, 1958. CrossrefGoogle Scholar6. BACHARACH T: Sarcoidosis: a clinical review of 111 cases. Amer. Rev. Resp. Dis. 84: 12-16, 1961. MedlineGoogle Scholar7. MCCORTWOODHAMILTONEHRLICH JJRHJBDE: Sarcoidosis. A clinical and roentgenologic study of twenty-eight proved cases. Arch. Intern. Med. (Chicago) 80: 293-321, 1947. CrossrefGoogle Scholar8. CODWELL H: Sarcoidosis: with special reference to diagnosis and prognosis. Quart. J. Med. 23: 29-55, 1954. MedlineGoogle Scholar9. MAYCOCKBERTRANDMORRISON RLPCE: Manifestations of sarcoidosis. Analysis of 145 patients, with a review of nine series selected from the literature. Amer. J. Med. 35: 67-89, 1963. CrossrefMedlineGoogle Scholar10. FAGERBERG SE: Sarcoidosis—a clinical, prognostic follow-up study. Acta Med. Scand. 146: 239-251, 1953. CrossrefMedlineGoogle Scholar11. SMELLIEHOYLE HC: The hilar lymph nodes in sarcoidosis with special reference to prognosis. Lancet 2: 66-70, 1957. CrossrefGoogle Scholar12. RUDBERG-ROOS I: The course and prognosis of sarcoidosis as observed in 296 cases. Acta Tuberc. Scand. Vol. 41: Suppl. 52, 1962. Google Scholar13. KLATSKINYESNER GR: Hepatic manifestations of sarcoidosis an other granulomatous diseases. A study based on histologic examination of tissue obtained by needle biopsy of the liver. Yale J. Biol. Med. 23: 207-248, 1950. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: JAMES P. NOLAN, M.D.; GERALD KLATSKIN, M.D., F.A.C.P.Affiliations: New Haven, ConnecticutFrom the Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn.This work was supported by Public Health Service Research Grant AM 05966 from the National Institute of Arthritis and Metabolic Diseases.Requests for reprints should be addressed to James P. Nolan, M.D., Department of Medicine, State University of New York at Buffalo, School of Medicine, Buffalo, N. Y. 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