Acute Cardiomyopathy Secondary to Intravenous Amphetamine Abuse
Authors: THOMAS D. CALL
Journal: Annals of Internal Medicine (1982)

Brief Reports1 October 1982Acute Cardiomyopathy Secondary to Intravenous Amphetamine AbuseTHOMAS D. CALL, M.D., JOSEPH HARTNECK, M.D., W. ANDREW DICKINSON, M.D., CLARK W. HARTMAN, M.D., ALAN G. BARTEL, M.D.THOMAS D. CALL, M.D.Search for more papers by this author, JOSEPH HARTNECK, M.D.Search for more papers by this author, W. ANDREW DICKINSON, M.D.Search for more papers by this author, CLARK W. HARTMAN, M.D.Search for more papers by this author, ALAN G. BARTEL, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-97-4-559 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIntravenous drug abuse can cause serious medical problems. Endocarditis and noncardiac pulmonary edema are the main cardiopulmonary complications of use of intravenous street drugs (1, 2). Previous reports have not shown any consistent direct myocardial complications secondary to use of these drugs (3). We report a case of a woman who developed acute cardiomyopathy with myocardial dysfunction and pulmonary edema immediately after intravenous amphetamine abuse. Possible causes for this severe cardiac abnormality, as well as its clinical importance, are discussed.A 22-year-old white woman presented to the energency room 10 hours after intravenous amphetamine use with chest pain and shortness...References1. HUSSEYKATZ HS. Infections resulting from narcotic addiction: report of 102 cases. Am J Med. 1950;9:186. CrossrefMedlineGoogle Scholar2. STEINBERGKARLINGER AJ. The clinical spectrum of heroin pulmonary edema. Arch Intern Med. 1968;122:122-7. CrossrefMedlineGoogle Scholar3. PARANTHAMANKAHN SF. Acute cardiomyopathy with recurrent pulmonary edema and hypotension following heroin overdosage. Chest. 1976;69:117-9. CrossrefMedlineGoogle Scholar4. RAAB W. The pathogenic significance of adrenalin and related substances in the heart muscle. Exp Med Surg. 1943;1:188. Google Scholar5. CHAPPELLRONABALAZSGAUDRY CGTR. Comparison of cardiotoxic actions of certain sympathomimetic amines. Can J Biochem Physiol. 1959;37:35-42. CrossrefMedlineGoogle Scholar6. REICHENBACHBENDIT DE. Catecholamines and cardiomyopathy: the pathogenesis and potential importance of myofibrillar degeneration. Hum Pathol 1970;1:125. CrossrefGoogle Scholar7. SZAKACSCANNON JA L-norephinephedrine myocarditis. Am J Cardiol. 1958;30:425-33. Google Scholar8. KLINE I. Myocardial alterations associated with pheochromocytomas. Am J Pathol. 1961;38:539-51. MedlineGoogle Scholar9. SMITHROCHEJAGUSCHHERDSON HAMP. Cardiomyopathy associated with amphetamine administration. Am Heart J. 1976;91:792-7. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. 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