Association of Hepatitis C and Diabetes Mellitus
Authors: Robert Paris
Journal: Annals of Internal Medicine (2001)

Letters17 July 2001Association of Hepatitis C and Diabetes MellitusRobert Paris, MD, MPHRobert Paris, MD, MPHWalter Reed Army Institute of Research, Silver Spring, MD 20910 (Paris)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-135-2-200107170-00017 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:The report by Mehta and colleagues (1) on the association between HCV infection and type 2 diabetes mellitus is intriguing. In the accompanying editorial, Alexander states that “a clear biological link … is not obvious” and summarizes the possible biological mechanisms that may be responsible for the observed link (2). One possibility that was not highlighted is the association between hepatitis C and iron overload, which may partly explain the observed findings (3). Of importance, in a different analysis of NHANES III data, Ford and Cogswell found a significant association between elevated serum ferritin level and newly ...References1. Mehta S, Brancati F, Sulkowski M, Strathdee S, Szklo M, Thomas D. Prevalence of type 2 diabetes mellitus among persons with hepatitis C virus infection in the United States. Ann Intern Med. 2000;133:592-9. [PMID: 11033586] LinkGoogle Scholar2. Alexander G. An association between hepatitis C virus infection and type 2 diabetes mellitus: what is the connection? [Editorial]. Ann Intern Med. 2000;133:650-2. [PMID: 11033595] LinkGoogle Scholar3. Adams P. Iron overload in viral and alcoholic liver disease. J Hepatol. 1998;28 Suppl 1 19-20. [PMID: 9575444] CrossrefMedlineGoogle Scholar4. Ford E, Cogswell M. Diabetes and serum ferritin concentration among U.S. adults. Diabetes Care. 1999;22:1978-83. [PMID: 10587829] CrossrefMedlineGoogle Scholar5. National Center for Health Statistics. Plan and Operation of the Third National Health and Nutrition Examination Survey, 1988-1994. DHHS publication no. PHS81-1317. Hyattsville, MD: National Center for Health Statistics; 1994. Google Scholar Author, Article, and Disclosure InformationAuthors: Robert Paris, MD, MPHAffiliations: Walter Reed Army Institute of Research, Silver Spring, MD 20910 (Paris) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoPrevalence of Type 2 Diabetes Mellitus among Persons with Hepatitis C Virus Infection in the United States Shruti H. Mehta , Frederick L. Brancati , Mark S. Sulkowski , Steffanie A. Strathdee , Moyses Szklo , and David L. Thomas An Association between Hepatitis C Virus Infection and Type 2 Diabetes Mellitus: What Is the Connection? Graeme J.M. Alexander Association of Hepatitis C and Diabetes Mellitus Shruti H. Mehta , Mark S. Sulkowski , and David L. Thomas Association of Hepatitis C and Diabetes Mellitus Hilla Knobler and A. Schattner Metrics Cited byGlucose abnormalities in non-alcoholic fatty liver disease and chronic hepatitis C virus infection: the role of iron overloadHyperferritinemia is a risk factor for steatosis in chronic liver diseaseGlucose Abnormalities in Patients with Hepatitis C Virus InfectionAssociation of Hepatitis C Virus Infection and Diabetes MellitusRelationship between serum ferritin, hepatic iron staining, diabetes mellitus and fibrosis progression in patients with chronic hepatitis C 17 July 2001Volume 135, Issue 2Page: 141-142KeywordsAntibodiesDiabetes mellitusFerritinHepatitis CInfectious hepatitisSerum ferritin levelsStatistical methodsType 2 diabetes ePublished: 17 July 2001 Issue Published: 17 July 2001 Copyright & PermissionsCopyright © 2001 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...