Cimetidine Interaction with Carbamazepine
Authors: NICOLE TELERMAN-TOPPET
Journal: Annals of Internal Medicine (1981)

Letters and Corrections1 April 1981Cimetidine Interaction with CarbamazepineNICOLE TELERMAN-TOPPET, M.D., MICHÈL E. DURET, M.D., CHRISTIAN COËRS, M.D.NICOLE TELERMAN-TOPPET, M.D.Search for more papers by this author, MICHÈL E. DURET, M.D.Search for more papers by this author, CHRISTIAN COËRS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-94-4-544_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: A recent report of Desmond and colleagues (1) showed delayed clearance of diazepam due to cimetidine. Similar interactions of cimetidine have been mentioned with antipyrine, oral anticoagulants, and hexobarbital. The list of the drugs thus affected by cimetidine is probably far from complete and could include carbamazepine, as indicated by the following report.A 89-year-old woman had been treated successfully with carbamazepine (600 mg/d) for 20 years for trigeminal neuralgia although short bouts of neuralgic pain were still experienced. Two weeks before admission, a gastric ulcer was radiologically diagnosed and treated by cimetidine (400 mg/d) without modification...Reference1. DESMONDPATWARDHANSCHENKERSPEEG PRSK. Cimetidine impairs elimination of chlordiazepoxide (Librium) in man. Ann Intern Med. 1980;93:266-8. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Free University of Brussels Brussels, Belgium PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByDrug Interactions with Agents Used to Treat Gastrointestinal DiseaseDrug Interactions with Agents Used in the Treatment of CNS DisordersMedical issues and emergencies in the dermatology officeEffect of Multiple Dose Omeprazole on the Pharmacokinetics of CarbamazepineInteraction between Isoniazid and Carbamazepine Potentiated by CimetidinePsychopharmacology in Patients with Hepatic and Gastrointestinal DiseaseThe effects of ranitidine and cimetidine on the pharmacokinetics and pharmacodynamics of metoprololInhibition of Carbamazepine and Phenytoin Metabolism by Nafimidone, a New Antiepileptic DrugH2-receptor antagonists as inhibitors of oxidative drug metabolism in vivoCimetidine and Carbamazepine: A Complex Drug InteractionThe Hepatic and Renal Mechanisms of Drug Interactions with CimetidineAntiepileptic drug toxicity: Definition and mechanism of actionEffect of cimetidine on digoxin disposition in peptic ulcer patientsRanitidine Does Not Alter Single-Dose Carbamazepin Pharmacokinetics in Healthy AdultsUsefulness and safety of cimetidine in patients receiving mexiletine for ventricular arrhythmiaThe Influence of Cimetidine on Single-Dose Carbamazepine PharmacokineticsAntiepileptic Drug InteractionsDrug interactions with cimetidine: An updateAnticonvulsant drugsInteractions Between Anticonvulsants and Other Commonly Prescribed DrugsEffects of cimetidine on carbamazepine auto- and hetero-induction in man.Histamine H2-receptor Antagonists in the Short- and Long-term Treatment of Duodenal UlcerEffect of cimetidine and ranitidine on carbamazepine and sodium valproate pharmacokineticsCimetidine-drug interactionsLack of interaction between cimetidine and carbamazepineEinflu� von Histamin H2-Rezeptorantagonisten auf die hepatische Elimination von ArzneimittelnEffect of Cimetidine on Phenytoin Serum LevelsReview of Cimetidine Drug InteractionsDrug Interactions and Reactions UpdateCimetidine as an Inhibitor of Drug Metabolism: Therapeutic Implications and Review of the LiteratureEffect of cimetidine on acetaminophen pharmacokinetics in ratsCimetidine in Elderly PatientsAntihistamines 1 April 1981Volume 94, Issue 4_Part_1Page: 544-544KeywordsAnticoagulantsDiazepamDrugsGastric ulcers Issue Published: 1 April 1981 PDF DownloadLoading ...