Liver Transplantation in HIV-Seropositive Individuals
Authors: Margaret V. Ragni, Steven H. Belle, KyungAh Im, John Fung, Guy Neff, Michelle Roland, Peter Stock, Nigel Heaton, Abhi Humar
Journal: Annals of Internal Medicine (2006)

Letters7 February 2006Liver Transplantation in HIV-Seropositive IndividualsMargaret V. Ragni, MD, MPH, Steven H. Belle, PhD, KyungAh Im, BS, John Fung, MD, PhD, Guy Neff, MD, Michelle Roland, MD, Peter Stock, MD, Nigel Heaton, MD, and Abhi Humar, MDMargaret V. Ragni, MD, MPHFrom the University of Pittsburgh, Pittsburgh, PA 15260; Cleveland Clinic Foundation, Cleveland, OH 44195; The University Hospital, Cincinnati, OH 45219; University of California, San Francisco, San Francisco, CA 94143; King's College, London WC2R 2LS, United Kingdom; and University of Minnesota Medical Center, Minneapolis, MN 55454.Search for more papers by this author, Steven H. Belle, PhDFrom the University of Pittsburgh, Pittsburgh, PA 15260; Cleveland Clinic Foundation, Cleveland, OH 44195; The University Hospital, Cincinnati, OH 45219; University of California, San Francisco, San Francisco, CA 94143; King's College, London WC2R 2LS, United Kingdom; and University of Minnesota Medical Center, Minneapolis, MN 55454.Search for more papers by this author, KyungAh Im, BSFrom the University of Pittsburgh, Pittsburgh, PA 15260; Cleveland Clinic Foundation, Cleveland, OH 44195; The University Hospital, Cincinnati, OH 45219; University of California, San Francisco, San Francisco, CA 94143; King's College, London WC2R 2LS, United Kingdom; and University of Minnesota Medical Center, Minneapolis, MN 55454.Search for more papers by this author, John Fung, MD, PhDFrom the University of Pittsburgh, Pittsburgh, PA 15260; Cleveland Clinic Foundation, Cleveland, OH 44195; The University Hospital, Cincinnati, OH 45219; University of California, San Francisco, San Francisco, CA 94143; King's College, London WC2R 2LS, United Kingdom; and University of Minnesota Medical Center, Minneapolis, MN 55454.Search for more papers by this author, Guy Neff, MDFrom the University of Pittsburgh, Pittsburgh, PA 15260; Cleveland Clinic Foundation, Cleveland, OH 44195; The University Hospital, Cincinnati, OH 45219; University of California, San Francisco, San Francisco, CA 94143; King's College, London WC2R 2LS, United Kingdom; and University of Minnesota Medical Center, Minneapolis, MN 55454.Search for more papers by this author, Michelle Roland, MDFrom the University of Pittsburgh, Pittsburgh, PA 15260; Cleveland Clinic Foundation, Cleveland, OH 44195; The University Hospital, Cincinnati, OH 45219; University of California, San Francisco, San Francisco, CA 94143; King's College, London WC2R 2LS, United Kingdom; and University of Minnesota Medical Center, Minneapolis, MN 55454.Search for more papers by this author, Peter Stock, MDFrom the University of Pittsburgh, Pittsburgh, PA 15260; Cleveland Clinic Foundation, Cleveland, OH 44195; The University Hospital, Cincinnati, OH 45219; University of California, San Francisco, San Francisco, CA 94143; King's College, London WC2R 2LS, United Kingdom; and University of Minnesota Medical Center, Minneapolis, MN 55454.Search for more papers by this author, Nigel Heaton, MDFrom the University of Pittsburgh, Pittsburgh, PA 15260; Cleveland Clinic Foundation, Cleveland, OH 44195; The University Hospital, Cincinnati, OH 45219; University of California, San Francisco, San Francisco, CA 94143; King's College, London WC2R 2LS, United Kingdom; and University of Minnesota Medical Center, Minneapolis, MN 55454.Search for more papers by this author, and Abhi Humar, MDFrom the University of Pittsburgh, Pittsburgh, PA 15260; Cleveland Clinic Foundation, Cleveland, OH 44195; The University Hospital, Cincinnati, OH 45219; University of California, San Francisco, San Francisco, CA 94143; King's College, London WC2R 2LS, United Kingdom; and University of Minnesota Medical Center, Minneapolis, MN 55454.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-144-3-200602070-00024 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:We were pleased that our recent paper (1) concerning liver transplantation in HIV-infected individuals was chosen for the 2005 Update in Gastroenterology and Hepatology (2), but we would like to clarify a few points about our paper and this evolving field.Contrary to the review by Drs. Koretz and Lipman, this was a prospective study of consecutively enrolled HIV-seropositive liver transplant recipients who underwent the procedure according to the same listing criteria as HIV-seronegative recipients. We felt compelled to carry out this study because 1) significant advances had occurred in the area of highly active antiretroviral therapy ...References1. Ragni MV, Belle SH, Im K, Neff G, Roland M, Stock P, et al. Survival of human immunodeficiency virus-infected liver transplant recipients. J Infect Dis. 2003;188:1412-20. [PMID: 14624365] CrossrefMedlineGoogle Scholar2. Koretz RL, Lipman TO. Update in gastroenterology and hepatology. Ann Intern Med. 2005;143:347-54. [PMID: 16144893] LinkGoogle Scholar3. Ragni MV, Bontempo FA, Lewis JH. Organ transplantation in HIV-positive patients with hemophilia [Letter]. N Engl J Med. 1990;322:1886-7. [PMID: 2348843] CrossrefMedlineGoogle Scholar4. Ragni MV, Belle SH. Impact of human immunodeficiency virus infection on progression to end-stage liver disease in individuals with hemophilia and hepatitis C virus infection. J Infect Dis. 2001;183:1112-5. [PMID: 11237838] CrossrefMedlineGoogle Scholar5. Stell DA, McAlister VC, Thorburn D. A comparison of disease severity and survival rates after liver transplantation in the United Kingdom, Canada, and the United States. Liver Transpl. 2004;10:898-902. [PMID: 15237374] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Margaret V. Ragni, MD, MPH; Steven H. Belle, PhD; KyungAh Im, BS; John Fung, MD, PhD; Guy Neff, MD; Michelle Roland, MD; Peter Stock, MD; Nigel Heaton, MD; Abhi Humar, MDAffiliations: From the University of Pittsburgh, Pittsburgh, PA 15260; Cleveland Clinic Foundation, Cleveland, OH 44195; The University Hospital, Cincinnati, OH 45219; University of California, San Francisco, San Francisco, CA 94143; King's College, London WC2R 2LS, United Kingdom; and University of Minnesota Medical Center, Minneapolis, MN 55454.Disclosures: None disclosed. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoUpdate in Gastroenterology and Hepatology Ronald L. Koretz and Timothy O. Lipman Liver Transplantation in HIV-Seropositive Individuals Ronald L. Koretz and Timothy O. Lipman Metrics Cited byHematopoietic Cell Therapy for Human Immunodeficiency Virus InfectionNational survey of provider opinions on controversial characteristics of liver transplant candidatesHepatitis virus infections 7 February 2006Volume 144, Issue 3Page: 223KeywordsHIV infectionsInfectious diseasesLiver diseasesLiver transplantationMorbidityProspective studiesPulmonary diseasesSafetySafety studiesTransplantation ePublished: 7 February 2006 Issue Published: 7 February 2006 Copyright & PermissionsCopyright © 2006 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...