Serologic Tests for Histoplasmosis
Authors: Eric S. Jacobson, Stephen E. Straus
Journal: Annals of Internal Medicine (1983)

Letters and Corrections1 April 1983Serologic Tests for HistoplasmosisERIC S. JACOBSON, M.D., PH.D, STEPHEN E. STRAUS, M.D.ERIC S. JACOBSON, M.D., PH.DSearch for more papers by this author, STEPHEN E. STRAUS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-98-4-560 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Wheat and associates (1) have shared a very large experience with histoplasmosis. They found that a sizeable minority of patients (approximately 20%) have cases that will not be identified by current serologic techniques. Such information defines the predictive value of a negative test result and confirms findings reported previously (2), but it is only half of the information needed to evaluate a diagnostic test. To use a diagnostic test intelligently, one must know the predictive value of both negative and positive results (3).In serologic tests for histoplasmosis, the predictive value of a positive test result has...References1. WHEATFRENCHKOHLER JMR. The diagnostic laboratory tests for histoplasmosis. Ann Intern Med. 1982;97:680-5. LinkGoogle Scholar2. TAYLORANDREWSCAMPBELL RCC. Histoplasmosis case finding: I. Survey procedures and clinical results: report of VA-armed forces cooperative study. In: Transactions of the 19th Conference on Chemotherapy and Tuberculosis. Washington, D.C.: Veterans Administration Central Office; 1960:282-7. Google Scholar3. RANSOHOFFFEINSTEIN DA. Problems of spectrum and bias in evaluating the efficacy of diagnostic tests. N Engl J Med. 1978;299:926-30. CrossrefMedlineGoogle Scholar4. JACOBSONSTRAUS ES. Reevaluation of diagnostic histoplasma serologies. Am J Med Sci. 1981;281:143-51. CrossrefMedlineGoogle Scholar5. LOWELLSHUFORD JE. The value of the skin test and complement fixation test in the diagnosis of chronic pulmonary histoplasmosis. Am Rev Respir Dis.me>:1069-75. MedlineGoogle Scholar1. BAUMANSMITH DC. Comparison of immunodiffusion and complement fixation tests in the diagnosis of histoplasmosis. J Clin Microbiol. 1975;2:77-80. CrossrefGoogle Scholar2. WARDWEEKSALLEN JMD. Acute histoplasmosis: clinical epidemiologic and serologic findings of an outbreak associated with exposure to a fallen tree. Am J Med. 1979;66:587-95. CrossrefMedlineGoogle Scholar3. GRINERMAYEWSKIMUSHLIN PRA. Selection and interpretation of diagnostic tests and procedures. Ann Intern Med. 1981;94(4 pt 2):453-600. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: ERIC S. JACOBSON, M.D., PH.D; STEPHEN E. STRAUS, M.D.Affiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited by2-Pyridyl-phosphine and -diphosphine complexes of nickel(0), their reactivity (including aqueous solution chemistry), and some related, incidental methylphosphonium iodides 1 April 1983Volume 98, Issue 4Page: 560-561KeywordsHistoplasmosis ePublished: 1 December 2008 Issue Published: 1 April 1983 PDF downloadLoading ...