The Heinz Body Hemolytic Anemias
Authors: JAMES H. JANDL
Journal: Annals of Internal Medicine (1963)

Editorials1 April 1963The Heinz Body Hemolytic AnemiasJAMES H. JANDL, M.D.JAMES H. JANDL, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-58-4-702 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptWith the development of the chemical industry in Germany about a century ago, a prevalent, often severe form of poisoning appeared among workers exposed to certain coal tar derivatives. This consisted of an acute hemolytic process having 2 characteristic features: a brown-to-green discoloration of the blood, creating a form of cyanosis when viewed in the patient; and the presence of inclusion bodies in the red cells that were evident on supravital staining and were called "Heinz bodies" (1). 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JANDL, M.D.Affiliations: Thorndike Memorial Laboratory Second and Fourth (Harvard) Medical Services Boston City Hospital Department of Medicine Harvard Medical School Boston, Massachusetts PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byCloning of the glucose 6-phosphate dehydrogenase gene from Plasmodium f alciparumEnhanced heinz body formation, cell lysis and anaemia in a Koala (Phascolarctos cinereus)The Bessis reticular cell, the hemoglobin ‘switch’ and the role of fetal hemoglobin: A hypothesisCorrelation between cataract and glutathione metabolismSeasonal and ontogenetic effects on methaemoglobin and reduced glutathione contents in the blood of reared baltic salmonInherited Erythrocyte Metabolic and Membrane DisordersGlucose-6-phosphate dehydrogenase and its relationship to mental retardationBiological autoxidation I. 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