Effect of Age, Tumor Risk, and Comorbidity in a U.S. Population–Based Cohort of Men With Prostate Cancer
Authors: Michael Froehner, Rainer Koch, Manfred P. Wirth
Journal: Annals of Internal Medicine (2013)

LettersSeptember 3, 2013Effect of Age, Tumor Risk, and Comorbidity in a U.S. Population–Based Cohort of Men With Prostate CancerMichael Froehner, MD, Rainer Koch, PhD, and Manfred P. Wirth, MDMichael Froehner, MDFrom Technical University of Dresden, Dresden, Germany.Search for more papers by this author, Rainer Koch, PhDFrom Technical University of Dresden, Dresden, Germany.Search for more papers by this author, and Manfred P. Wirth, MDFrom Technical University of Dresden, Dresden, Germany.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-159-5-201309030-00017 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:The population-based cohort in the article by Daskivich and colleagues (1) does not necessarily represent the best mimic of relevant clinical scenarios in men with early prostate cancer awaiting a treatment decision. Population-based cohorts include sick patients with an overproportional effect on medium-term survival rates (for example, patients with severe cardiopulmonary disease, dementia, or second malignancies precluding curative treatment of prostate cancer) who would otherwise be eliminated by selection during clinical decision making. Incorporating comorbid conditions in counseling for patients with early prostate cancer requires knowing their prognostic effect on treatment subgroups.In our radical prostatectomy series ...References1. Daskivich TJ, Fan KH, Koyama T, Albertsen PC, Goodman M, Hamilton AS, et al. Effect of age, tumor risk, and comorbidity on competing risks for survival in a U.S. population-based cohort of men with prostate cancer. Ann Intern Med. 2013;158:709-17 LinkGoogle Scholar2. Charlson ME, Pompei P, Ales KL, and MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40:373-83. [PMID: 3558716] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Technical University of Dresden, Dresden, Germany.Disclosures: None disclosed. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoEffect of Age, Tumor Risk, and Comorbidity on Competing Risks for Survival in a U.S. Population–Based Cohort of Men With Prostate Cancer Timothy J. Daskivich , Kang-Hsien Fan , Tatsuki Koyama , Peter C. Albertsen , Michael Goodman , Ann S. Hamilton , Richard M. Hoffman , Janet L. Stanford , Antoinette M. Stroup , Mark S. Litwin , and David F. Penson Effect of Age, Tumor Risk, and Comorbidity in a U.S. Population–Based Cohort of Men With Prostate Cancer Timothy J. Daskivich , Mark S. Litwin , and David F. Penson Metrics September 3, 2013Volume 159, Issue 5Page: 370KeywordsCancer treatmentDeath ratesDecision makingDementiaLife expectancyLongitudinal studiesProstate cancerProstate diseasesRadical prostatectomy ePublished: 3 September 2013 Issue Published: September 3, 2013 Copyright & PermissionsCopyright © 2013 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...