Low Blood Selenium Concentration in Crohn Disease
Authors: KLAUS LOESCHKE
Journal: Annals of Internal Medicine (1987)

Letters and Corrections1 June 1987Low Blood Selenium Concentration in Crohn DiseaseKLAUS LOESCHKE, M.D., AUGUST KÖNIG, M.D., SUSANNE TREBERT HAEBERLIN, Dr. rer. nat., FRANZ LUX, Dr. rer. nat.KLAUS LOESCHKE, M.D.Search for more papers by this author, AUGUST KÖNIG, M.D.Search for more papers by this author, SUSANNE TREBERT HAEBERLIN, Dr. rer. nat.Search for more papers by this author, FRANZ LUX, Dr. rer. nat.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-106-6-908_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Selenium deficiency has been reported in areas where soils and plants are poor in this trace element, and in patients on long-term parenteral nutrition (1, 2). Because selenium is absorbed preferentially in the ileum (3), we wondered whether patients with Crohn disease might be prone to low blood selenium concentrations.Venous blood was drawn from subjects into heparinized syringes. Selenium was determined blindly using neutron activation analysis. In one control subject, the variation coefficient of selenium concentrations of six samples taken over several weeks was 3%.Eleven controls aged 20 to 60 years had whole blood selenium...References1. LEVANDER O. Clinical consequences of low selenium intake and its relationship to vitamin E. Ann NY Acad Sci. 1982;393:70-80. CrossrefMedlineGoogle Scholar2. BAPTISTABISTRIANBLACKBURN RBG. Suboptimal selenium status in home parenteral nutrition patients with small bowel resections. J Parent Ent Nutr. 1984;8:542-5. CrossrefMedlineGoogle Scholar3. ARDÜSERWOLFFRAMSCHARRER FSE. Active absorption of selenate by rat ileum. J Nutr. 1985;115:1203-8. CrossrefMedlineGoogle Scholar4. JACOBSONPLANTIN SL. Concentration of selenium in plasma and erythrocytes during total parenteral nutrition in Crohn's disease. Gut. 1985;26:50-4. CrossrefMedlineGoogle Scholar5. SCHELENZ R. Intake of Zn, Mn and Se by adult females: a total diet study. In: BRÄTTER P, SCHRAMEL P, eds. Trace Element-Analytical Chemistry in Medicine and Biology. New York: Walter de Gruyter; 1984;73-89. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: University of Munich Technical University of Munich Munich Federal Republic of Germany PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited BySelenoproteins and oxidative stress-induced inflammatory tumorigenesis in the gutMalnutrition und MalabsorptionAntioxidant and immune status in active Crohn's disease. A possible relationshipMeasurement of Selenium in Clinical SpecimensSelenium deficiency inhibits prostacyclin release and enhances production of platelet activating factor by human endothelial cellsTrace Element Deficiencies in Inflammatory Bowel DiseaseHyposelenaemia: patients with gastrointestinal diseases are at riskSelenium: Clinical Significance and Analytical Concepts 1 June 1987Volume 106, Issue 6Page: 908-908KeywordsAttentionBloodCrohn's diseaseIleumNutritionSelenium Issue Published: 1 June 1987 PDF DownloadLoading ...