Copper Deficiency Anemia and Prolonged Enteral Feeding
Authors: Jiro Masugi
Journal: Annals of Internal Medicine (1994)

Letters1 September 1994Copper Deficiency Anemia and Prolonged Enteral FeedingJiro Masugi, MD, Masahiko Amano, MD, and Tsuneo Fukuda, MDJiro Masugi, MDSearch for more papers by this author, Masahiko Amano, MDSearch for more papers by this author, and Tsuneo Fukuda, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-121-5-199409010-00021 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Copper deficiency is a rare disease because of the ubiquitous distribution of copper and low daily requirements. Copper deficiency has been reported in patients who receive total parenteral nutrition [1], who have the short-bowel syndrome [2], and who receive oral zinc therapy [3] and in premature infants [4]. We describe a patient who developed copper deficiency anemia after long-term enteral feeding.A 77-year-old woman was hospitalized in July 1993 because of severe macrocytic anemia. She had an erythrocyte count of 110 × 104/µL, a hemoglobin level of 4.4 g/dL, a hematocrit of 12.8%, and a mean corpuscular ...References1. Hirase N, Abe Y, Sadamura S, Yufu Y, Muta K, Umemura T, et al. Anemia and neutropenia in a case of copper deficiency: role of copper in normal hematopoiesis. Acta Haematol. 1992; 87:195-7. Google Scholar2. Dunlap WM, James GW, Hume DM. Anemia and neutropenia caused by copper deficiency. Ann Intern Med. 1987; 80:470-6. Google Scholar3. Summerfield AL, Steinberg FU, Gonzalez JG. Morphologic findings in bone marrow precursor cells in zinc-induced copper deficiency anemia. Am J Clin Pathol. 1992; 97:665-8. Google Scholar4. Al-Rashid RA, Spangler J. Neonatal copper deficiency. N Engl J Med. 1971; 285:841-3. Google Scholar5. AMA Department of Foods and Nutrition. Guidelines for essential trace element preparations for parenteral use. A statement by an expert panel. JAMA. 1979; 241:2051-4. Google Scholar Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byCopper Deficiency: Causes, Manifestations, and TreatmentAnemia Therapy II: HematinicsVitamins and MineralsCopper deficiency with increased hematogones mimicking refractory anemia with excess blastsIn Long-Term Bedridden Elderly Patients with Dietary Copper Deficiency, Biochemical Markers of Bone Resorption Are Increased with Copper Supplementation during 12 WeeksCocoa Supplementation for Copper Deficiency Associated with Tube Feeding NutritionRecovery and Maintenance of Copper Levels in Geriatric Patients on Enteral Feeding for a Prolonged PeriodProgressive severe anemia due to copper deficiency five years after subarachnoid hemorrhageTrace metals and the elderlyCopper deficiency with pancytopenia due to enteral nutrition through jejunostomyBiochemical Parameters of Nutrition 1 September 1994Volume 121, Issue 5Page: 386KeywordsAnemiaBone marrowDietInfantsMean corpuscular volumeNeutropeniaNeutrophilsTotal parenteral nutritionVitamin CZinc Issue Published: 1 September 1994 Copyright & PermissionsCopyright © 1994 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...