Airway Adrenaline in Patients with Severe Cardiac Disease
Authors: Gideon Paret, Danny Lotan, Zohar Barzilay
Journal: Annals of Internal Medicine (2001)

Letters1 May 2001Airway Adrenaline in Patients with Severe Cardiac DiseaseGideon Paret, MD, Danny Lotan, MD, and Zohar Barzilay, MDGideon Paret, MDThe Chaim Sheba Medical Center; Ramatgan 52621, Israel (Paret, Lotan, Barzilay)Search for more papers by this author, Danny Lotan, MDThe Chaim Sheba Medical Center; Ramatgan 52621, Israel (Paret, Lotan, Barzilay)Search for more papers by this author, and Zohar Barzilay, MDThe Chaim Sheba Medical Center; Ramatgan 52621, Israel (Paret, Lotan, Barzilay)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-134-9_Part_1-200105010-00023 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Raymondos and colleagues (1) report a substantial increase in blood pressure after airway administration of adrenaline in 34 patients undergoing general anesthesia. We noted a discrepancy between the data reported in the Results section of the text and those presented in the authors' Figure (1): The Figure clearly demonstrates that an undecipherable number of patients had an initial decrease in blood pressure, a response that is not mentioned anywhere in the text. We have previously shown that an initial decrease in blood pressure, such as that displayed in the authors' Figure, is caused by β2 stimulation and ...References1. Raymondos K, Panning B, Leuwer M, Brechelt G, Korte T, Niehaus M, et al . Absorption and hemodynamic effects of airway administration of adrenaline in patients with severe cardiac disease. Ann Intern Med. 2000;132:800-3. [PMID: 0010819703] LinkGoogle Scholar2. Paret G, Vaknin Z, Ezra D, Ben-Abraham R, Manistersky Y, Vardi A, Lotan D, et al . Endotracheal adrenaline: should the recommended dose be reconsidered? Journal of Prehospital Care. 1998;2:1-5. MedlineGoogle Scholar3. Mazkereth R, Paret G, Ezra D, Aviner S, Peleg E, Rosenthal T, et al . Epinephrine blood concentrations after peripheral bronchial versus endotracheal administration of epinephrine in dogs. Crit Care Med. 1992;20:1582-7. [PMID: 0001424703] CrossrefMedlineGoogle Scholar4. McCrirrick A, Kestin I. Haemodynamic effects of tracheal compared with intravenous adrenaline. Lancet. 1992;340:868-70. [PMID: 0001357295] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Gideon Paret, MD; Danny Lotan, MD; Zohar Barzilay, MDAffiliations: The Chaim Sheba Medical Center; Ramatgan 52621, Israel (Paret, Lotan, Barzilay) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoAbsorption and Hemodynamic Effects of Airway Administration of Adrenaline in Patients with Severe Cardiac Disease Konstantinos Raymondos , Bernhard Panning , Martin Leuwer , Guido Brechelt , Thomas Korte , Michael Niehaus , Jürgen Tebbenjohanns , and Siegfried Piepenbrock Airway Adrenaline in Patients with Severe Cardiac Disease Konstantinos Raymondos , Bernhard Panning , and Siegfried Piepenbrock Airway Adrenaline in Patients with Severe Cardiac Disease Konstantinos Raymondos , Bernhard Panning , and Siegfried Piepenbrock Metrics Cited byEndotracheal Epinephrine: A Call for Larger DosesEndotracheal Epinephrine: A Call for Larger DosesDeleterious Airway Administration of AdrenalineDeleterious Airway Administration of AdrenalineDeleterious Airway Administration of AdrenalineDeleterious Airway Administration of Adrenaline 1 May 2001Volume 134, Issue 9_Part_1Page: 796-797KeywordsBlood pressureEpinephrineHeartHypotensionResearch designResearch laboratoriesSurgerySystolic pressureVasoconstrictionVasodilation ePublished: 1 May 2001 Issue Published: 1 May 2001 Copyright & PermissionsCopyright © 2001 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...