Immune Aspects of the Glomerulonephritis Associated with Pulmonary Hemmorhage
Authors: ROBERT L. SCHEER
Journal: Annals of Internal Medicine (1964)

Article1 June 1964Immune Aspects of the Glomerulonephritis Associated with Pulmonary HemmorhageROBERT L. SCHEER, M.D., MURRAY A. GROSSMAN, M.D.ROBERT L. SCHEER, M.D., MURRAY A. GROSSMAN, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-60-6-1009 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe simultaneous appearance of pulmonary hemorrhage and an acute glomerulonephritis has been observed often enough to warrant the conclusion that this represents a distinct clinical entity (1-12). This disease has been called Goodpasture's syndrome, although there is some doubt that the patient described by Goodpasture in 1919 actually met the criteria for the syndrome (1). Numerous reports have emphasized the fulminant course of the disease. The etiology of this syndrome is obscure, but the nature of the tissue reaction suggests that an immune mechanism is at least partially responsible for its pathogenesis. Immunologic studies of two women who died of...References1. GOODPASTURE EW: Significance of certain pulmonary lesions in relation to etiology of influenza. Amer. J. Med. Sci. 158: 863, 1919. CrossrefGoogle Scholar2. PARKINRUSTEDBURCHELLEDWARDS TWIEHBJE: Hemorrhagic and interstitial pneumonitis with nephritis. Amer. J. Med. 18: 220, 1955. CrossrefMedlineGoogle Scholar3. STANTONTANGE MCJD: Goodpasture's syndrome (pulmonary hemorrhage associated with glomerulonephritis). Aust. Ann. Med. 7: 132, 1958. CrossrefMedlineGoogle Scholar4. RUSBYWILSON NLC: Lung purpura with nephritis. Quart. J. Med. 29: 501, 1960. MedlineGoogle Scholar5. LEXOWSIGSTAD PH: Glomerulonephritis with initial lung purpura. Acta Med. Scand. 168: 405, 1960. CrossrefMedlineGoogle Scholar6. 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