Tamoxifen and Carcinoid Tumor
Authors: CARL F. MYERS
Journal: Annals of Internal Medicine (1982)

Letters and Corrections1 March 1982Tamoxifen and Carcinoid TumorCARL F. MYERS, M.D., WILLIAM B. ERSHLER, M.D., MARK A. TANNENBAUM, A.B., RICHARD BARTH, M.D.CARL F. MYERS, M.D., WILLIAM B. ERSHLER, M.D., MARK A. TANNENBAUM, A.B., RICHARD BARTH, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-96-3-383_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Keshgegian and Wheeler (1) have recently demonstrated the presence of estrogen receptors in two carcinoid tumors. Other investigators (2) reported symptomatic improvement with tamoxifen therapy in a patient with carcinoid syndrome, although objective evidence of disease regression was not presented. We report a patient who obtained a significant objective response to tamoxifen therapy.A 59-year-old man had had intermittent diarrhea and crampy abdominal pain diagnosed as "colitis" 15 years before admission. These symptoms had remained stable until 6 years before admission when his diarrhea had increased to once or twice a day and intermittent hot flashes and...References1. KESHGEGIAN A and WHEELER J. Estrogen receptor protein in malignant carcinoid tumor: a report of two cases. Cancer. 1980;45:293-6. CrossrefMedlineGoogle Scholar2. STATHOPOULOS G, KARVOUNTZIS G, and YIOTIS J. Tamoxifen in carcinoid syndrome. N Engl J Med. 1981;305:52. CrossrefMedlineGoogle Scholar3. MOERTEL G and HANLEY J. Combination chemotherapy trials for metastatic carcinoid tumor. Proc Am Assoc Cancer Res/Am Soc Clin Onc. 1978;19:322. Google Scholar4. MCGUIRE W, HORWITZ K, PEARSON O, and SEGALOGG A. Current status of estrogen and progesterone receptors in breast cancer. Cancer. 1977;39:2934-47. CrossrefMedlineGoogle Scholar5. POSEY L, MORGAN L, and BEAZLEY R. Estrogen receptors. J Am Med Assoc. 1977;238:2599. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: CARL F. MYERS, M.D.; WILLIAM B. ERSHLER, M.D.; MARK A. TANNENBAUM, A.B.; RICHARD BARTH, M.D.Affiliations: Vermont Regional Cancer Center and the University of Vermont Burlington, VT 05401 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySexual Dimorphism in Small-intestinal Neuroendocrine Tumors: Lower Prevalence of Mesenteric Disease in Premenopausal WomenPathogenesis and Clinical Management of Mesenteric Fibrosis in Small Intestinal Neuroendocine Neoplasms: A Systematic ReviewUpdate on Pathophysiology, Treatment, and Complications of Carcinoid SyndromeSmall intestinal neuroendocrine tumours and fibrosis: an entangled conundrumTherapeutic Options for Gastrointestinal CarcinoidsCurrent Status of Gastrointestinal CarcinoidsCarcinoid A Comprehensive ReviewPartial Remission of Carcinoid Tumor in Response to CyproheptadineStuart P. Leitner, MD, Paul Greenberg, MD, Linda A. Danieu, MD, Richard A. Michaelson, MDTherapy of the Malignant Carcinoid SyndromeTherapy of the Malignant Carcinoid Syndrome and Metastatic Islet Cell CarcinomaTherapeutic Considerations for the Malignant Carcinoid SyndromeChemotherapy of metastatic carcinoid and islet cell tumors: A reviewMetastatic carcinoid tumors and the carcinoid syndrome: A selective review of chemotherapy and hormonal therapyTherapy of Metastatic Carcinoid Tumor and the Carcinoid SyndromeTamoxifen Therapy for Metastatic Carcinoid Tumor: A Negative StudyCHARLES G. MOERTEL, M.D., PAUL F. ENGSTROM, M.D., ALLAN J. SCHUTT, M.D. 1 March 1982Volume 96, Issue 3Page: 383-383KeywordsAbdominal painCarcinoid tumorColitisDiarrheaEstrogens ePublished: 1 December 2008 Issue Published: 1 March 1982 PDF downloadLoading ...