Update in Infectious Diseases
Authors: Gerald L. Mandell
Journal: Annals of Internal Medicine (2001)

Updates from the Annual Session20 November 2001Update in Infectious DiseasesGerald L. Mandell, MDGerald L. Mandell, MDFrom University of Virginia Health Sciences Center, Charlottesville, Virginia.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-135-10-200111200-00010 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail In this Update, I cover developments in the management of hepatitis C, which is most often first encountered by general internists and treated by hepatologists rather than infectious disease consultants. I also describe several recent reports on the current state of antibiotic resistance and promising new approaches to this expanding problem. Following that discussion are sections on prevalent infections, including the common cold, sinusitis, and influenza, and on less common infectious disorders that nevertheless pose an increasing threat; for example, those that move from animals to humans (rabies, Creutzfeldt–Jakob disease) and those that are translocating from one part of the ...References1. Kenny-Walsh E. Clinical outcomes after hepatitis C infection from contaminated anti-D immune globulin. Irish Hepatology Research Group. N Engl J Med. 1999;340:1228-33. [PMID: 10210705] CrossrefMedlineGoogle Scholar2. Datz C, Cramp M, Haas T, Dietze O, Nitschko H, Froesner G, et al . The natural course of hepatitis C virus infection 18 years after an epidemic outbreak of non-A, non-B hepatitis in a plasmapheresis centre. Gut. 1999;44:563-7. [PMID: 10075966] CrossrefMedlineGoogle Scholar3. Heathcote EJ, Shiffman ML, Cooksley WG, Dusheiko GM, Lee SS, Balart L, et al . Peginterferon alfa-2a in patients with chronic hepatitis C and cirrhosis. N Engl J Med. 2000;343:1673-80. [PMID: 11106716] CrossrefMedlineGoogle Scholar4. Schafer DF, Sorrell MF. Conquering hepatitis C, step by step [Editorial]. N Engl J Med. 2000;343:1723-4. [PMID: 11106723] CrossrefMedlineGoogle Scholar5. Feikin DR, Schuchat A, Kolczak M, Barrett NL, Harrison LH, Lefkowitz L, et al . Mortality from invasive pneumococcal pneumonia in the era of antibiotic resistance, 1995-1997. Am J Public Health. 2000;90:223-9. [PMID: 10667183] CrossrefMedlineGoogle Scholar6. Rieux V, Carbon C, Azoulay-Dupuis E. Complex relationship between acquisition of β-lactam resistance and loss of virulence in Streptococcus pneumoniae . J Infect Dis. 2001;184:66-72. [PMID: 11398111] CrossrefMedlineGoogle Scholar7. Ruiz-González A, Falguera M, Nogués A, Rubio-Caballero M. Is Streptococcus pneumoniae the leading cause of pneumonia of unknown etiology? A microbiologic study of lung aspirates in consecutive patients with community-acquired pneumonia. Am J Med. 1999;106:385-90. [PMID: 10225239] CrossrefMedlineGoogle Scholar8. Rosón B, Carratalà J, Verdaguer R, Dorca J, Manresa F, Gudiol F. Prospective study of the usefulness of sputum Gram stain in the initial approach to community-acquired pneumonia requiring hospitalization. Clin Infect Dis. 2000;31:869-74. [PMID: 11049763] CrossrefMedlineGoogle Scholar9. Gwaltney JM. Acute community acquired bacterial sinusitis: to treat or not to treat. Can Respir J. 1999;6 Suppl A 46A-50A. [PMID: 10202234] MedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Gerald L. Mandell, MDAffiliations: From University of Virginia Health Sciences Center, Charlottesville, Virginia.Corresponding Author: Gerald L. Mandell, MD, Division of Infectious Diseases, University of Virginia Health Sciences Center, Building MR4, Room 2112, Charlottesville, VA 22908. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoCorrection: Update in Infectious Diseases Metrics Cited byBacterial infection in compensated viral cirrhosis impairs 5-year survival (ANRS CO12 CirVir prospective cohort)Correction: Update in Infectious Diseases 20 November 2001Volume 135, Issue 10 Page: 897-905 Keywords Amphotericin Antimicrobials Bats Drugs Infectious diseases Lymphocytes Pneumonia Prions Vaccines Zinc ePublished: 20 November 2001 Issue Published: 20 November 2001 Copyright & PermissionsCopyright © 2001 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...