Polydipsia and Polyuria Associated with Quadriplegia
Authors: VISITH SITPRIJA
Journal: Annals of Internal Medicine (1966)

Article1 July 1966Polydipsia and Polyuria Associated with QuadriplegiaVISITH SITPRIJA, M.D., PH.D., CHARN POCHANUGOOL, M.D., CHANYO BENYAJATI, M.D., CHARAS SUWANWELA, M.D.VISITH SITPRIJA, M.D., PH.D.Search for more papers by this author, CHARN POCHANUGOOL, M.D.Search for more papers by this author, CHANYO BENYAJATI, M.D.Search for more papers by this author, CHARAS SUWANWELA, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-65-1-62 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIt was observed by Claude Bernard that resection of the splanchnic nerves results in an increased urine flow (1). Although a number of laboratory and clinical investigations have been carried out to study the effect of denervation of the kidney on renal function (2-7), the mechanism responsible for diuresis remains unsettled. Some investigators have suggested that renal denervation depresses tubular transport of sodium (2-4); others, from the evidence that there is a rise in glomerular filtration rate and renal flow after denervation, have concluded that natriuresis is the result of changes in renal hemodynamics (5-7).While attention has been focused...References1. CALDWELLMARXROWNTREE JMHLG: Renal function after bilateral denervation of the kidney in normal dogs. J. Urol. 25: 351, 1931. CrossrefGoogle Scholar2. SARTORIUSBURLINGTON OWH: Acute effects of denervation on kidney function in the dog. Amer. J. Physiol. 185: 407, 1956. CrossrefMedlineGoogle Scholar3. KAPLANRAPOPORT SAS: Urinary excretion of sodium and chloride after splanchnicotomy; effect on the proximal tubule. Amer. J. Physiol. 164: 175, 1951. CrossrefMedlineGoogle Scholar4. BLAKE WD: Relative roles of glomerular filtration and tubular reabsorption in denervation diuresis. Amer. J. Physiol. 202: 777, 1962. CrossrefMedlineGoogle Scholar5. KAMMLEVINSKY DENG: The mechanism of denervation natriuresis. J. Clin. Invest. 44: 93, 1965. CrossrefMedlineGoogle Scholar6. BRICKERSTRAFFONMAHONEYMERRILL NSRAEPJP: The functional capacity of the kidney denervated by autotransplantation in the dog. J. Clin. Invest. 37: 185, 1958. CrossrefMedlineGoogle Scholar7. JONTZSUSHUMACKERBOUNOUS JGCSHBG: Influence of renal denervation upon renal blood flow. Surg. Gynec. Obstet. 110, 622, 1960. MedlineGoogle Scholar8. BROWNPYZIKFINKLE MSJR: Causes of polyuria and polydipsia in patients with injuries of the cervical spinal cord. Neurology 9: 877, 1959. CrossrefMedlineGoogle Scholar9. HOLMESCRANDALLDWYERSHORT JHJIWCWF: The relation of salivary flow to the state of hydration in patients with uremia and renal failure. Trans. Amer. Soc. Artif. Intern. Organs 6: 152, 1960. MedlineGoogle Scholar10. CARTERROBBINS ACJ: The use of hypertonic saline infusions in the differential diagnosis of diabetes insipidus and psychogenic polydipsia. J. Clin. Endocr. 7: 753, 1947. CrossrefGoogle Scholar11. WOLF AV: Thirst: Physiology of the Urge to Drink and Problems of Water Lack. Charles C Thomas, Publisher, Springfield, Ill., 1958. Google Scholar12. CANNON WB: The physiological basis of thirst. Proc. Roy. Soc. [Biol.] 90: 283, 1918. Google Scholar13. STEGGERDA FR: The relation of dry mouth to thirst in the human. Amer. J. Physiol. 126: 635, 1939. Google Scholar14. MONTGOMERY NF: The role of the salivary glands in the thirst mechanism. Amer. J. Physiol. 96: 221, 1931. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: VISITH SITPRIJA, M.D., PH.D.; CHARN POCHANUGOOL, M.D.; CHANYO BENYAJATI, M.D.; CHARAS SUWANWELA, M.D.Affiliations: Bangkok,From the Department of Medicine and Division of Neurosurgery, Chulalongkorn Hospital Medical School, Bangkok, Thailand.Requests for reprints should be addressed to Visith Sitprija, M.D., Department of Medicine, Chulalongkorn Hospital Medical School, Bangkok, Thailand. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byProfound Hyponatraemia in QuadriplegiaHyponatremia in Spinal Cord InjuryCase Report: Severe Hyponatremia in Spinal Cord InjuryDiabetes insipidus in a quadriplegic patientDisorders of Antidiuretic Hormone Secretion 1 July 1966Volume 65, Issue 1Page: 62-68KeywordsDenervationHemodynamicsHospital medicineKidneysNervesNeurosurgeryResearch laboratoriesSalivaSodiumUrine ePublished: 1 December 2008 Issue Published: 1 July 1966 PDF downloadLoading ...