Microsporidan Hepatitis in the Acquired Immunodeficiency Syndrome
Authors: S Terada, K R Reddy, L J Jeffers, A Cali, E R Schiff
Journal: Annals of Internal Medicine (1987)

Brief Reports1 July 1987Microsporidan Hepatitis in the Acquired Immunodeficiency SyndromeSOICHIRO TERADA, M. D., K. RAJENDER REDDY, M.D., LENNOX J. JEFFERS, M.D., ANN CALI, Ph.D., EUGENE R. SCHIFF, M.D.SOICHIRO TERADA, M. D., K. RAJENDER REDDY, M.D., LENNOX J. JEFFERS, M.D., ANN CALI, Ph.D., EUGENE R. SCHIFF, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-107-1-61 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptVarious infections occur in the acquired immunodeficiency syndrome (AIDS); the liver can become infected by mycobacteria, fungi, and viruses (1, 2). We report a rare case of hepatitis due to a microsporidan protozoa of the genus Encephalitozoon (formerly not identified as a separate genus from Nosema) in a patient with AIDS. Encephalitozoonosis is a chronic, often latent, protozoan infection that occurs in various mammals (3, 4). Until now, microsporida have only been reported to cause myositis (5) and infect enterocytes (6) in patients with AIDS.A 35-year-old homosexual man was well until 4 months before his last hospitalization. He developed...References1. GORDONREDDYGOULD SKE. The spectrum of liver disease in the acquired immunodeficiency syndrome. J Hepatol. 1986;2:475-84. CrossrefMedlineGoogle Scholar2. WATANABEREDDYJEFFERSDICKINSONO'CONNELLSCHIFF SKLGME. Electron microscopic evidence of non-A, non-B hepatitis markers and virus-like particles in immunocompromised humans. Hepatology. 1984;4:628-32. CrossrefMedlineGoogle Scholar3. SHADDUCKPAKES JS. Encephalitozoonosis (nosematosis) and toxoplasmosis. Am J Pathol. 1971;64:657-71. MedlineGoogle Scholar4. SHADDUCKWATSONPAKESCALI JWSA. Animal infectivity of Encephalitozoon cuniculi. J Parasitol. 1979;65:123-9. CrossrefMedlineGoogle Scholar5. LEDFORDOVERMANGONZALVOCALIMESTERLOCKEY DMAAWR. 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