Expanding the Use of Thrombolytic Therapy for Acute Myocardial Infarction
Authors: J. Ward Kennedy
Journal: Annals of Internal Medicine (1990)

Editorials15 December 1990Expanding the Use of Thrombolytic Therapy for Acute Myocardial InfarctionJ. Ward Kennedy, MDJ. Ward Kennedy, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-113-12-907 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe general impression in the United States is that thrombolytic therapy for acute myocardial infarction is underutilized. Grines and DeMaria (1), as well as others (2-4), have recently estimated that only about 10% of eligible patients with acute myocardial infarction receive thrombolytic therapy. Because thrombolytic therapy is now accepted as the best initial treatment for many patients with acute myocardial infarction, it is important to understand the reasons for its underutilization and find ways to correct the situation.In this issue ofAnnals, Muller and Topol (5) review the current selection and exclusion criteria for the use of thrombolytic therapy...References1. GrinesDeMaria CA. Optimal utilization of thrombolytic therapy for acute myocardial infarction: concepts and controversies. J Am Coll Cardiol. 1990;16:223-31. CrossrefMedlineGoogle Scholar2. U.S. Hospital Drug and Diagnosis Audit Thrombolytic Market. Phoenix, Arizona; 1988. Google Scholar3. . Monthly Vital Statistics Report. Washington, D.C.: Government Printing Office; 1986;34:13. Google Scholar4. HlatkyCotugnoO'ConnorMarkPryorCaliff MHCDDR. Adoption of thrombolytic therapy in the management of acute myocardial infarction. Am J Cardiol. 1988;61:510-4. CrossrefMedlineGoogle Scholar5. MullerTopol DE. Selection of patients with acute myocardial infarction for thrombolytic therapy. Ann Intern Med. 1990;113:949-60. LinkGoogle Scholar6. . Effectiveness of intravenous thrombolytic treatment in acute myocardial infarction. Lancet. 1986;1:397-402. MedlineGoogle Scholar7. . Randomized trial of intravenous streptokinase, oral aspirin, both or neither among 17, 187 cases of suspected acute myocardial infarction: ISIS-2. Lancet. 1988;77:349-60. Google Scholar8. WilcoxOlssonSkenevon der LippeJensenHampton RCAGGJ. Trial of tissue plasminogen activator for mortality reduction in acute myocardial infarction. Lancet. 1988;1:525-30. CrossrefGoogle Scholar9. KennedyAtkinsGoldstein JJS. Recent changes in management of acute myocardial infarction: implications for emergency care physicians. J Am Coll Cardiol. 1988;11:446-9. CrossrefMedlineGoogle Scholar10. MidgetteO'ConnorBaronBell AGJJ. Effect of intravenous streptokinase on short-term mortality in patients with suspected acute myocardial infarction. Ann Intern Med. 1990;113:961-8. LinkGoogle Scholar11. MauriGaspariniBarbonaglia FML. Prognostic significance of the extent of myocardial injury in acute myocardial infarction treated by streptokinase (the GISSI trial). Am J Cardiol. 1989;63:1291-5. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: University of Washington Seattle, WA 98195 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByPharmacological profile of survivors of acute myocardial infarction at Turkish academic hospitalsDirect comparison of aspirin plus hirudin aspirin plus heparin, and aspirin alone among 12,000 patients with acute myocardial infarction not receiving thrombolysis: Rationale and design of the First American Study of Infarct Survival (ASIS-1)Trends in the use of drag therapies in patients with acute myocardial infarction: 1988 to 1992Audit of thrombolysis initiated in an accident and emergency department.Thrombolytic therapy in acute myocardial infarction: Some reservationsPrevention of Severe Neurologic Events in the Thrombolytic EraIncreased prescription of thrombolytic treatment to elderly patients with suspected acute myocardial infarction associated with audit.Survey of practicing cardiologists in maryland on their choice of thrombolytic therapy for acute myocardial infarctionIschemic stroke and intracranial hemorrhage following thrombolytic therapy for acute myocardial infarction: A risk-benefit analysisThe early diagnosis of heart attacks: a neurocomputational approach 15 December 1990Volume 113, Issue 12Page: 907-908KeywordsAcute myocardial infarctionMuscular dystrophiesPatients Issue Published: 15 December 1990 PDF DownloadLoading ...