Treatment of Adult Acute Nonlymphocytic Leukemia—1980
Authors: CLARA D. BLOOMFIELD
Journal: Annals of Internal Medicine (1980)

Editorials1 July 1980Treatment of Adult Acute Nonlymphocytic Leukemia—1980CLARA D. BLOOMFIELD, M. D.CLARA D. BLOOMFIELD, M. D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-93-1-133 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptImpressive advances in the treatment of adult acute nonlymphocytic leukemia have occurred during the last 10 years. The percentage of patients achieving complete remission has increased. The median durations of these remissions have lengthened, and the percentage of longterm survivors has risen. Ten years ago, a 25% remission rate for adults was exceptional. Today complete remission rates of more than 50% are regularly achieved in large cooperative group trials (1,2), and using combinations that include an anthracycline antibiotic (daunorubicin hydrochloride or doxorubicin hydrochloride), cytarabine, and 6-thioguanine or 6-mercaptopurine, complete remission rates of more than 80% have been reported by several...References1. YATESGLIDEWELLWIERNIKHOLLAND JOPJ. A CALGB study of adriamycin vs daunorubicin induction and a four vs eight week maintenance in acute myelocytic leukemia. Proc Am Soc Clin Oncol. 1980;21:350. Abstract. Google Scholar2. BENNETTBEGGSARTIANOTARTAGLIACARBONE JCGAP. The chemotherapy of adult acute myeloid leukemia. Proc Am Soc Clin Oncol. 1980;21:434. Abstract. Google Scholar3. UZUKALIONGYAMAGATA YSS. Treatment of adult acute nonlymphoblastic leukemia using intermittent combination chemotherapy with daunomycin, cytosine arabinoside, 6-mercaptopurine and prednisolone-DCMP two step therapy. 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BLUME, M.D. 1 July 1980Volume 93, Issue 1_Part_1Page: 133-135KeywordsAcute myeloid leukemiaAntibiotics Issue Published: 1 July 1980 PDF DownloadLoading ...