Dysphagia and Vertical Nystagmus in Magnesium Deficiency
Authors: ISAM A. HAMED
Journal: Annals of Internal Medicine (1978)

Brief Reports1 August 1978Dysphagia and Vertical Nystagmus in Magnesium DeficiencyISAM A. HAMED, M.D., ROBERT D. LINDEMAN, M.D.ISAM A. HAMED, M.D., ROBERT D. LINDEMAN, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-89-2-222 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptMagnesium deficiency should be anticipated as a complication in patients with extensive intestinal resections (short-bowel syndrome) (1-2). In man, it produces neuromuscular hyperexcitability with muscle weakness, tremors, athetoid movements, and fasciculations (3). Tetany, generalized tonic-clonic or focal seizures, and positive Chvostek's signs also may be present. Some patients develop irritability, depression, and even psychotic behavior. In patients with experimentally-induced magnesium deficiency, abnormal electromyograms were consistently observed with short-duration, rapid-firing myopathic potentials (3). The peripheral effects of magnesium are to decrease liberation of acetylcholine at the neuromuscular junction and sympathetic ganglia; magnesium deficiency is associated with an increase in neuronal excitability...References1. FLETCHER R, HENLY A, SAMMONS H, and SQUIRE J: Case of magnesium deficiency following massive intestinal resection. Lancet 1:522-525, 1960 CrossrefMedlineGoogle Scholar2. OPIE L, HUNT B, and FINLAY J: Massive small bowel resection with malabsorption and negative magnesium balance. Gastroenterology 47:415-420, 1964 CrossrefMedlineGoogle Scholar3. SHILS M: Experimental production of magnesium deficiency in man. Ann NY Acad Sci 162:847-855, 1969 CrossrefMedlineGoogle Scholar4. SMITH W: Magnesium deficiency in the surgical patient. Am J Cardiol 13:667-670, 1963 CrossrefGoogle Scholar5. ZIEVE L: Role of cofactors in the treatment of malnutrition as exemplified by magnesium. Yale J Biol Med 48:229-237, 1975 MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: ISAM A. HAMED, M.D.; ROBERT D. LINDEMAN, M.D.Affiliations: Oklahoma City Veterans Administration Hospital University of Oklahoma Health Sciences Center Oklahoma City, Oklahoma PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byMineral bioaccessibility in 3D printed gels based on milk/starch/ĸ-carrageenan for dysphagic peoplePosterior Reversible Encephalopathy Syndrome due to Hypomagnesemia: A Case Report and Literature ReviewEsophageal Involvement in Systemic DiseasesMetabolic EncephalopathiesPrevalence of hypomagnesemia (HM) in a geriatric long-term care (LTC) settingMetabolic EncephalopathiesMagnesium Deficiency: Pathophysiologic and Clinical OverviewMagnesium Homeostasis and Clinical Disorders of Magnesium DeficiencyEndocrine EmergenciesMagnesium deficiency: Recognition and treatment in the emergency medicine settingMagnesium metabolism in health and diseaseEndocrine EmergenciesProphylaxis against hypomagnesaemia induced by cis-platinum combination chemotherapyPharyngoesophageal Swallowing Disorders and the Pharyngoesophageal SphincterPharyngeal Dysphagia in Alcoholic MyopathyLAWRENCE D. WEBER, M.D., DAVID J. NASHEL, M.D., MARK H. MELLOW, M.D.Vomiting due to gastric stasis as the presenting feature in thyrotoxicosisMagnesium: Physiology, clinical disorders, and therapyMotor Disorders of the EsophagusBiochemistry and behaviour: systemic aspects of neurological disturbancesMagnesium — The forgotten electrolyteCLINICAL SIGNS OF MAGNESIUM DEFICIENCY 1 August 1978Volume 89, Issue 2Page: 222-223KeywordsAcetylcholineBehaviorDysphagiaElectromyographyEpileptic seizuresFasciculationsGangliaMagnesiumNystagmus ePublished: 1 December 2008 Issue Published: 1 August 1978 PDF downloadLoading ...