Thromboangiitis Obliterans and Arteriosclerosis Obliterans
Authors: JAMES R. MCPHERSON
Journal: Annals of Internal Medicine (1963)

Article1 September 1963Thromboangiitis Obliterans and Arteriosclerosis ObliteransClinical and Prognostic DifferencesJAMES R. MCPHERSON, M.D., JOHN L. JUERGENS, M.D., RAY W. GIFFORD JR., M.D.JAMES R. MCPHERSON, M.D., JOHN L. JUERGENS, M.D., RAY W. GIFFORD JR., M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-59-3-288 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThromboangiitis obliterans (Buerger's disease) has been defined as a segmental, inflammatory, occlusive disease which primarily affects small or medium-sized arteries and veins in the extremities of young adults, usually males (1). The most frequent clinical manifestation of thromboangiitis obliterans is ischemia of one or both feet with greatly diminished or absent pedal pulsations; the proximal arterial pulsations are usually normal during the early stages of the disease. There is often evidence of ischemia of one or more fingers, and episodes of recurrent segmental thrombophlebitis of superficial nonvaricose veins of the extremities may occur. Almost always there appears to be a...References1. ALLENBARKERHINES EVNWEA: Peripheral Vascular Diseases, 3rd ed., W. B. Saunders Company, Philadelphia, 1962, p. 343. Google Scholar2. FISHER CM: Cerebral thromboangiitis obliterans (including a critical review of the literature). Medicine 36: 169, 1957. CrossrefMedlineGoogle Scholar3. WESSLERMINGGUREWICHFREIMAN SSVDG: A critical evaluation of thromboangiitis obliterans: the case against Buerger's disease. New Eng. J. Med. 262: 1149, 1960. CrossrefMedlineGoogle Scholar4. HOROWITZ O: Buerger's disease retrieved. (Editorial). Ann. Intern. Med. 55: 341, 1961. LinkGoogle Scholar5. BARKER NW: The case for retention of the diagnostic category "thromboangiitis obliterans." (Editorial). Circulation 25: 1, 1962. CrossrefMedlineGoogle Scholar6. MCKUSICKHARRISOTTESONGOODMANSHELLEYBLOODWELL VAWSOERMWMRD: Buerger's disease: a distinct clinical and pathologic entity. JAMA 181: 5, 1962. CrossrefGoogle Scholar7. BERKSONGAGE JRP: Calculation of survival rates for cancer. Proc. Mayo Clin. 25: 270, 1950. MedlineGoogle Scholar8. SCHADTHINESJUERGENSBARKER DCEAJLNW: Chronic atherosclerotic occlusion of the femoral artery. JAMA 175: 937, 1961. CrossrefMedlineGoogle Scholar9. JUERGENSBARKERHINES JLNWEA: Arteriosclerosis obliterans: review of 520 cases with special reference to pathogenic and prognostic factors. Circulation 21: 188, 1960. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Rochester, MinnesotaFrom the Section of Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minnesota (Drs. Mc-Pherson and Juergens) and Department of Hypertension, Cleveland Clinic Foundation, Cleveland, Ohio (Dr. Gifford).Requests for reprints should be addressed to Mayo Clinic, Rochester, Minnesota. 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