High Frequency of Antibodies to the Hepatitis C Virus among Patients with Hepatocellular Carcinoma
Authors: Victor Vargas, Luis Castells, Juan I. Esteban
Journal: Annals of Internal Medicine (1990)

Letters and Corrections1 February 1990High Frequency of Antibodies to the Hepatitis C Virus among Patients with Hepatocellular CarcinomaVictor Vargas, MD, Luis Castells, MD, Juan I. Esteban, MDVictor Vargas, MDSearch for more papers by this author, Luis Castells, MDSearch for more papers by this author, Juan I. Esteban, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-112-3-232_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editor: Although evidence implicates the hepatitis B virus in the pathogenesis of hepatocellular carcinoma (1), other factors such as alcohol or chronic infection by non-A, non-B hepatitis agents have also been implicated, particularly in developed countries. Several documented cases of hepatocellular carcinoma following chronic non-A, non-B hepatitis have been reported in developed countries (2).The isolation of the major bloodborne non-A, non-B hepatitis agent, hepatitis C virus (HCV), by cloning (3) has led to the development of assays for the detection of specific antibodies (4). In a previous report (5), we showed that HCV infection is present in...References1. Lieberman H and Shafritz D. Persistent hepatitis B virus infection and hepatocellular carcinoma. In: Popper H, Schaffner F, eds. Progress in Liver Diseases, v 8. Orlando, Florida: Grune & Stratton, Inc.; 1986:395-415. Google Scholar2. Tabor E. Hepatocellular carcinoma: possible etiologies in patients without serologic evidence of hepatitis B virus infection. J Med Virol. 1989;27:1-6. CrossrefMedlineGoogle Scholar3. Choo Q, Kuo G, Weiner A, Overby L, Bradley D, and Houghton M. Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science. 1989;244:359-62. CrossrefMedlineGoogle Scholar4. Kuo G, Choo Q, and Alter H. An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis. Science. 1989;244:362-4. CrossrefMedlineGoogle Scholar5. Esteban J, Esteban R, and Viladomiu L. Hepatitis C virus antibodies among risk groups in Spain. Lancet. 1989;2:294-7. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: Victor Vargas, MD; Luis Castells, MD; Juan I. Esteban, MD PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byEpidemiology of Viruses Associated with Human CancerInfección por los virus de la hepatitis en el paciente trasplantadoCharacteristics and course of small hepatocellular carcinomas in patients with hepatitis C virus types 1 and 2Trends in mortality from primary liver cancer in EuropeHepatocellular carcinoma in patients with HCVHepatitis C virus and hepatocellular carcinomaNatural history and pathogenesis of hepatitis C virus related hepatocellular carcinomaCharacteristics of hepatocellular carcinoma in ItalyThe Role of Hepatitis C Virus in Hepatocellular CarcinomaEpidemiological characteristics and risk factors of hepatocellular carcinomaInduction of apoptosis in a human hepatocellular carcinoma cell line by a neutralizing antibody to transforming growth factor-?Hepatitis C virus and hepatocellular carcinomaHepatitis B and C Viruses and Hepatocellular CarcinomaHepatitis B and C viruses in the development of hepatocellular carcinomaHepatitis C virus and hepatocellualr carcinomaThe role of hepatitis C virus in chronic hepatitis B virus infectionEpidemiology of hepatitis C virus infectionHepatitis C virus infection in hepatocellular carcinoma. Detection of plus-strand and minus-strand viral RNADoes hepatitis C virus infection contribute to hepatocellular carcinoma in hong kong?Hepatocellular carcinomaAnti-HCV antibody in Chinese cirrhotic patients with or without hepatocellular carcinoma: Relation to multitransfusionAnti-HCV positive hepatocellular carcinoma in cirrhosisHepatitis C Virus Infection as a Risk Factor for Hepatocellular Carcinoma in Patients with Cirrhosis A Case-Control StudyRosa Giovanna Simonetti, MD, Calogero Cammà, MD, Felice Fiorello, MD, Mario Cottone, MD, Maria Rapicetta, BS, Liliana Marino, BS, Germana Fiorentino, BS, Antonio Craxì, MD, Annarita Ciccaglione, BS, Roberto Giuseppetti, BS, Tommaso Stroffolini, MD, Luigi Pagliaro, MDImproved detection of hepatitis c virus antibodies in high-risk populationsHepatitis C virus and hepatocellular carcinomaProblematiche Inerenti L'epatite C Nei Centri DialisiHigh Rate of Infectivity and Liver Disease in Blood Donors with Antibodies to Hepatitis C VirusJuan Ignacio Esteban, MD, Juan Carlos López-Talavera, MD, Juan Genescà, MD, Pedro Madoz, MD, Luis Viladomiu, MD, Eduardo Muñiz, MD, Carmen Martin-Vega, MD, Manuel Rosell, MD, Helena Allende, MD, Xavier Vidal, MD, Antonio González, MD, Jose Manuel Hernández, MD, Rafael Esteban, MD, Jaime Guardia, MDSeroprevalence of antibody against hepatitis C virus (anti-HCV) in various groups of individuals in KoreaCorrection: Frequency of Antibodies to Hepatitis C Virus in Hepatocellular CarcinomaVictor Vargas, MD 1 February 1990Volume 112, Issue 3Page: 232-233KeywordsAlcoholsAntibodiesChronic hepatitisCloningHepatitis B virusHepatitis C virusHepatocellular carcinomaInfectious hepatitisPathogenesis ePublished: 1 December 2008 Issue Published: 1 February 1990 PDF downloadLoading ...