Pulmonary Edema and Salicylate Intoxication
Authors: PHILIP R. DAVIS
Journal: Annals of Internal Medicine (1974)

Letters1 April 1974Pulmonary Edema and Salicylate IntoxicationPHILIP R. DAVIS, M.D., ROBERT E. BURCH, M.D.PHILIP R. DAVIS, M.D.Search for more papers by this author, ROBERT E. BURCH, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-80-4-553_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: The association of salicylate intoxication and pulmonary edema is mentioned in some standard texts (1, 2). Nevertheless, a literature review turned up only one case report of pulmonary edema, in the absence of heart disease, associated with salicylate intoxication (3). We report two fatal cases of salicylate intoxication with pulmonary edema and no heart disease.CASE 1A 40-year-old black man was admitted complaining of severe dyspnea. He regularly took up to 20 aspirin tablets daily. His pulse was 110; blood pressure, 142/82 mm Hg; respirations, 35 to 45/min; and temperature, 37.4 °C [99.4 °F]. Cyanosis of...References1. GOODMANGILMAN LA: The Pharmacological Basis of Therapeutics, 4th ed. New York, The MacMillan Co., 1970 Google Scholar2. SMITHSMITH MP: The Salicylates—A Critical Bibliographic Review. New York, Interscience Publishers, 1966, pp 262-272 Google Scholar3. GRANVILLE-GROSSMANSERGEANT KH: Pulmonary edema due to salicylate intoxification. Lancet 1:575-577, 1960 CrossrefMedlineGoogle Scholar4. WORTHENARGANOSIWADLOWSKI MBW: Mechanisms of intracisternal veratrine pulmonary edema. Dis Chest 55:45-48, 1969 CrossrefMedlineGoogle Scholar5. HILL J: Salicylate intoxication. N Engl J Med 288:1110-1113, 1973 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Department of Medicine Omaha Veterans Administration Hospital and Creighton University School of Medicine Omaha, Nebraska PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByCurrent Management of Salicylate-Induced Pulmonary EdemaSalicylate poisoning: An evidence-based consensus guideline for out-of-hospital managementPathology of interstitial lung diseaseSalicylatesDrug-Induced Pulmonary DisordersBronchoalveolar Lavage in Recurrent Aspirin-induced Adult Respiratory Distress SyndromeCAUSES OF THE ADULT RESPIRATORY DISTRESS SYNDROME—CLINICAL RECOGNITIONSalicylate-Induced Pulmonary Edema Clinical Features and PrognosisJOHN E. HEFFNER, M.D., STEVEN A. SAHN, M.D.Salicylate Toxicity Following Therapeutic Doses in Young ChildrenPROLAMINE SOLUTION TO BLOCK PANCREATIC DUCTFATAL RESPIRATORY-DISTRESS SYNDROME AND SALICYLATE INTOXICATION IN A TWO-YEAR-OLDHypovolemia, pulmonary edema and protein changes in severe salicylate poisoningADULT RESPIRATORY-DISTRESS SYNDROME IN SALICYLATE INTOXICATIONAdult respiratory distress syndrome precipitated by massive salicylate poisoningAntipyretic analgesicsUnrecognized Adult Salicylate IntoxicationROBERT J. ANDERSON, M.D., DANIEL E. POTTS, M.D., PATRICIA A. GABOW, M.D., BARRY H. RUMACK, M.D., ROBERT W. SCHRIER, M.D., F.A.C.P.Salicylate and Pulmonary EdemaMARTIN G. TWEEDDALE, M.D., PH.D; F.R.C.P.(C)Pulmonary Edema and SalicylatesCHARLES K. TASHIMA, M.D., MARGARET ROSE, M.D. 1 April 1974Volume 80, Issue 4Page: 553-554KeywordsBlood pressureCardiovascular therapyDyspneaEdemaHeart rateIntoxicationPulmonary diseasesRespirationSalicylatesTemperature Issue Published: 1 April 1974 PDF DownloadLoading ...