Blood Gases in Pulmonary Edema
Authors: SYANIAL K. DATTA
Journal: Annals of Internal Medicine (1972)

Letters, Comments, and Corrections1 June 1972Blood Gases in Pulmonary EdemaSYANIAL K. DATTA, M.D.SYANIAL K. DATTA, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-76-6-1045 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: In their recent article (1) Aberman and Fulop describe multiple factors in pulmonary edema that can cause hypercapnia. They postulate that these factors act by influencing the well-known equation (2), alveolar PCO2= K· VCO2/VA where VCO2is carbon dioxide output, VA is alveolar ventilation, and K is a constant. This equation shows that if the alveolar ventilation is halved, the alveolar (and therefore arterial) PCO2is doubled, other factors being constant. This equation assumes that mixed alveolar and mixed arterial PCO2Sare equal and can be applied to a single lung unit or a homogeneous normal...References1. ABERMAN A and FULOP M: The metabolic and respiratory acidosis of acute pulmonary edema. Ann Intern Med 76:173-184, 1972 LinkGoogle Scholar2. RAHN H and FENN W: A Graphical Analysis of the Respiratory Gas Exchange. The O2-CO2 Diagram. Washington D.C., American Physiological Society, 1955 Google Scholar3. GREEN D: Pulmonary edema, in Respiration, vol. 2, section 3 of Handbook of Physiology, edited by FENN WO, RAHN H. Washington D.C., American Physiological Society, 1964, p. 1594 Google Scholar4. EBERT R: The lung in congestive heart failure. Arch Intern Med 107:450-459, 1961 CrossrefMedlineGoogle Scholar5. WEST J: Causes of carbon dioxide retention in lung disease. N Engl J Med 284:1232-1236, 1971 CrossrefMedlineGoogle Scholar6. SHARP J, GERAINT T, and BUNNELL I: Ventillatory mechanics in pulmonary edema in man. J Clin Invest 37:111-117, 1958 CrossrefMedlineGoogle Scholar7. WEST J: Gas exchange when one lung region inspires from another. J Appl Physiol 30:479-483, 1971 CrossrefMedlineGoogle Scholar8. HOGG J, MACKLEM P, and THURLBECK W: The resistance of collateral channels in excised human lungs. J Clin Invest 48:421-431, 1969 CrossrefMedlineGoogle Scholar9. BROWN R, WOOLCOCK A, and VINCENT N: Physiological effects of experimental airway obstruction with beads. J Appl Physiol 27:328-335, 1969 CrossrefMedlineGoogle Scholar1. ANKENEY J, HUBAY C, and TILLOTSON F: The effect of changes in pulmonary circulation on collateral ventilation. Surg Forum 1950, pp. 25-33 MedlineGoogle Scholar2. CALL E, LINDSKOG G, and LIEBOW A: Some physiologic and pharmacologic aspects of collateral ventilation. J Thorac Cardiovasc Surg 49:1015-1025, 1965 CrossrefMedlineGoogle Scholar3. MACKLEM P: Airways obstruction and collateral ventilation. Physiol Rev 51:368-435, 1971 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: SYANIAL K. DATTA, M.D.Affiliations: Department of Hematology and Internal Medicine Cook County Hospital Chicago, Ill. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byChronic hypoxia attenuates ischemia-reperfusion-induced increase in pulmonary vascular resistanceLactic Acidosis in Pulmonary Edema due to Left Ventricular FailureMILFORD FULOP, MICHAEL HOROWITZ, M.D., ARNOLD ABERMAN, M.D., ERNST R. JAFFÉ, M.D. 1 June 1972Volume 76, Issue 6Page: 1045-1046KeywordsBloodCarbon dioxideEdemaHypercapniaLungsPartial pressure of carbon dioxide ePublished: 1 December 2008 Issue Published: 1 June 1972 PDF downloadLoading ...