Acromegaly and Multiple Myeloma
Authors: Erik Hägg
Journal: Annals of Internal Medicine (1988)

Letters and Corrections1 September 1988Acromegaly and Multiple MyelomaErik Hägg, MD, Kjell Asplund, MD, Jan Holm, MDErik Hägg, MDSearch for more papers by this author, Kjell Asplund, MDSearch for more papers by this author, Jan Holm, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-109-5-437_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editor: Acromegaly has been reported to be associated with cancer and premalignant adenomatous polyps of the colon (1, 2). We have seen three patients in whom acromegaly and multiple myeloma coexisted.A woman born in 1918 had clinically overt acromegaly diagnosed in 1969 with high levels of serum growth hormone (GH) (46µg/L; normal, < 10), but a sellar roentgenogram was normal. She declined treatment until 1975 when pituitary irradiation therapy was given (45 Gy) with decreasing serum GH levels. In 1978, an IgG kappa myeloma stage I A was diagnosed that progressed to stage III A in 1980....References1. KleinParveenGalaverVanthiel IGJD. Colonic polyps in patients with acromegaly. Ann Intern Med. 1982;97:27-30. LinkGoogle Scholar2. ItuartePetrini EJ. Hershman JM. Acromegaly and colon cancer. Ann Intern Med. 1984;101:627-8. LinkGoogle Scholar3. MoonSimpsonLiEvans HMCH. Neoplasms in rats treated with pituitary growth hormone. I. Pulmonary and lymphatic tissues. Cancer Res. 1950;10:297-308. MedlineGoogle Scholar4. FischerJobPreeceUnderwood DJML. Leukaemia in patients treated with growth hormone [Letter]. Lancet. 1988;1:1159-60. MedlineGoogle Scholar5. Hutchison G. Late neoplastic changes following medical irradiation. Cancer. 1976;37:1102-7. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: University Hospital Umeå Sweden PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAcute Lymphoblastic Leukemia Diagnosed in a Patient with AcromegalyMultiple Myeloma in a Patient with AcromegalyAcute myeloid leukemia and colon carcinoma during the course of acromegalyHematologic neoplasias and acromegalyAcromegaly: Re-thinking the cancer riskGrowth Hormone Receptor Expression is Up-Regulated During Tumorigenesis of Human Colorectal CancerAcromegaly Associated with Monoclonal Gammopathy of Undetermined Significance (MGUS)Systemic Complications of Acromegaly: Epidemiology, Pathogenesis, and ManagementCancer Risk Following Growth Hormone Use in ChildhoodTransformation of a MGUS to Overt Multiple Myeloma: The Possible Role of a Pituitary Macroadenoma Secreting High Levels of Insulin-like Growth Factor 1 (IGF-1)Use of Growth Hormone and Growth Hormone Secretagogues in Aging: Help or HarmLetter to the EditorCancer in AcromegalyAcromegaly and Non-Hodgkin’s LymphomaAssociation of acromegaly and two malignancies: Colorectal cancer and non-Hodgkin's lymphomaAcromegaly and NeoplasiaAcromegaly and gastrointestinal cancer 1 September 1988Volume 109, Issue 5Page: 437-438KeywordsAcromegalyColonGrowth hormoneMultiple myelomaMyeloma ePublished: 1 December 2008 Issue Published: 1 September 1988 PDF downloadLoading ...