Thyroid Disease, Dermatitis Herpetiformis, and Splenic Atrophy
Authors: PETER N. FOSTER
Journal: Annals of Internal Medicine (1985)

Letters and Corrections1 July 1985Thyroid Disease, Dermatitis Herpetiformis, and Splenic AtrophyPETER N. FOSTER, B.M., B.CH.PETER N. FOSTER, B.M., B.CH.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-103-1-157_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Cunningham and Zone (1) have recently reported a significant but unexplained association between clinical thyroid disease, thyroid autoantibodies, and dermatitis herpetiformis. The authors postulate an immunogenetic predisposition to the development of these abnormalities and mention the increased prevalence of HLA-B8 and HLA-DRw3 in patients with dermatitis herpetiformis and those with autoimmune thyroid disease. The authors do not appear to have considered the possible role of associated splenic atrophy, which occurs in up to one third of patients with dermatitis herpetiformis (2), in the development of these autoimmune findings. Splenic atrophy is associated with an increased frequency of...References1. CUNNINGHAMZONE MJ. Thyroid abnormalities in dermatitis herpetiformis. Ann Intern Med. 1985;102:194-6. LinkGoogle Scholar2. PETTITHOFFBRANDSEAHFRY JAPL. Splenic atrophy in dermatitis herpetiformis. Br Med J. 1972;28:438-440. CrossrefGoogle Scholar3. WARDROPDAGGLEESINGHDYERMOFFAT CJFHJA. Immunological abnormalities in splenic atrophy. Lancet. 1975;2:4-7. CrossrefMedlineGoogle Scholar4. BULLENHALLGOWLANDRAJAHLOSOWSKY ARGSM. Hyposplenism, adult coeliac disease and autoimmunity. Gut. 1981;22:28-33. CrossrefMedlineGoogle Scholar1. PETTITHOFFBRANDSEAHFRY JAPL. Splenic atrophy in dermatitis herpetiformis. Br Med J 1972;2:438-40. CrossrefMedlineGoogle Scholar2. WALDROPDAGGLEESINGHDYETMOFFAT CJFHJA. Immunological abnormalities in splenic atrophy. Lancet. 1975;2:4-7. CrossrefMedlineGoogle Scholar3. BULLENHALLGOWLANDRAJAHLOSOWSKY ARGSM. Hyposplenism, adult coeliac disease, and autoimmunity. Gut. 1980;21:28-33. Google Scholar4. ROMBALLWEIGLE CW. Splenic role in the regulation of immune responses. Cell Immunol. 1977;34:376-84. CrossrefMedlineGoogle Scholar5. LOCKWOODWORLLEDGENICHOLASCOTTONPETERS CSACD. Reversal of impaired splenic function in patients with nephritis or vasculitis (or both) by plasma exchange. N Engl J Med. 1979;300:524-30. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: PETER N. FOSTER, B.M., B.CH.Affiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byObesity (Medoroga) in AyurvedaSonographic Prevalence of Liver Steatosis and Biliary Tract Stones in Patients with Inflammatory Bowel Disease: Study of 511 Subjects at a Single CenterElevated Triglyceride and Decreased High Density Lipoprotein Level in Carbon Disulfide Workers in TaiwanHyposplenismSecular changes in stature, weight, fatness, overweight, and obesity in urban African American adolescents from the mid-1950's to the mid-1990'sPersonal Health-Risk Predictors of Occupational Injury Among 3415 Municipal EmployeesWomen dieters of normal weight: their motives, goals, and risks.THE DIFFICULT PROBLEM OF A GROIN LUMP IN A MORBIDLY OBESE PATIENTHealth Problems of Adolescents in Holon, IsraelMultivariate prediction of total and cardiovascular mortality in an obese Polynesian population.The prevalence of thyroid autoantibodies in dermatitis herpetiformis 1 July 1985Volume 103, Issue 1Page: 157-157KeywordsAtrophyAutoantibodiesThyroidThyroid diseases ePublished: 1 December 2008 Issue Published: 1 July 1985 PDF downloadLoading ...