Adrenal Insufficiency and Interleukin-2 Therapy
Authors: Louis A. VanderMolen, John W. Smith, Dan L. Longo, Ronald G. Steis, Peter Kremers, Mario Sznol
Journal: Annals of Internal Medicine (1989)

Letters and Corrections15 July 1989Adrenal Insufficiency and Interleukin-2 TherapyLouis A. VanderMolen, MD, John W. Smith II, MD, Dan L. Longo, MD, Ronald G. Steis, MD, Peter Kremers, MD, Mario Sznol, MDLouis A. VanderMolen, MDSearch for more papers by this author, John W. Smith II, MDSearch for more papers by this author, Dan L. Longo, MDSearch for more papers by this author, Ronald G. Steis, MDSearch for more papers by this author, Peter Kremers, MDSearch for more papers by this author, Mario Sznol, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-111-2-185_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editor: Rao and colleagues (1) recently reviewed bilateral massive adrenal hemorrhage; however, its occurrence during interleukin-2 therapy has not been reported.A 52-year-old man developed right flank pain in October 1987. He had a normal blood pressure without orthostatic changes. Cardiac, pulmonary, and neurologic examinations were normal. An abdominal computed tomographic (CT) scan revealed an 11.4 X 9.6 cm right renal mass with direct extension into the liver, ablation and involvement of the right adrenal gland, and metastasis to the left adrenal gland. Results of a routine biochemical profile, complete blood count, and differential cell count were normal....References1. RaoVagnucciAmico RAJ. Bilateral massive adrenal hemorrhage: early recognition and treatment. Ann Intern Med. 1989;101:227-35. LinkGoogle Scholar2. GaynorVitekStricklin ELL. The hemodynamic effects of treatment with interleukin-2 and lymphokine-activated killer cells. Ann Intern Med. 1988;109:953-8. LinkGoogle Scholar3. LeeLotzeSkibber RMJ. Cardiorespiratory effects of immunotherapy with interleukin-2. J Clin Oncol. 1989;7:7-20. CrossrefMedlineGoogle Scholar4. MichieEberleinSpriggs HTD. Interleukin-2 initiates metabolic responses associated with critical illness in humans. Ann Surg. 1988;208:493-501. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: Louis A. VanderMolen, MD; John W. SmithII, MD; Dan L. Longo, MD; Ronald G. Steis, MD; Peter Kremers, MD; Mario Sznol, MDAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byEndocrine Toxicities of ImmunotherapyAldesleukinManagement of toxicities associated with high-dose interleukin-2 and biochemotherapyCYTOKINES AND CYTOKINE MODULATORSENDOCRINE AND METABOLIC ADVERSE EFFECTS OF NON-HORMONAL AND NON-METABOLIC DRUGSAldesleukinInterleukin-2Bilateral massive adrenal hemorrhageAutoimmune Addison’s Disease after Treatment With interleukin-2 and Tumor-Infiltrating LymphocytesCytostatics and immuno-suppressive drugsBlood and blood products 15 July 1989Volume 111, Issue 2Page: 185-185KeywordsAdrenal glandsBlood cellsBlood pressureCardiac ablationComplete blood countComputed axial tomographyHemorrhageLiver ePublished: 1 December 2008 Issue Published: 15 July 1989 PDF downloadLoading ...