Panaortitis Complicating Hodgkin's Disease
Authors: JOSEPH F. FRAUMENI
Journal: Annals of Internal Medicine (1967)

Case Studies1 December 1967Panaortitis Complicating Hodgkin's DiseaseJOSEPH F. FRAUMENI JR., M.D., F.A.C.P., JOHN C. HERWEG, M.D., JOHN M. KISSANE, M.D.JOSEPH F. FRAUMENI JR., M.D., F.A.C.P., JOHN C. HERWEG, M.D., JOHN M. KISSANE, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-67-6-1242 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe etiology of nonsyphilitic inflammatory diseases of the aorta is unknown, although some cases occur in association with rheumatic or rheumatoid diseases (1). Recently, there have been reports of aortitis associated with malignant lymphoma in three young people. The aortitis in two instances was believed to result directly from radiation therapy of the lymphoma (2, 3), but in one case it developed before treatment (4). This report concerns a girl with Hodgkin's disease who developed aortitis and the relationship of this complication to radiation therapy and the lymphoma.CASE REPORTAn 8-year-old white girl was well until September 1953, when...References1. SCHRIREASHERSON VRA: Arteritis of the aorta and its major branches. Quart. J. Med. 33: 439, 1964. MedlineGoogle Scholar2. THOMASFORBUS EWD: Irradiation injury to the aorta and the lung. Arch. Path. (Chicago) 67: 256, 1959. MedlineGoogle Scholar3. HEIDENBERGLUPOVITCHTARR WJAN: "Pulseless disease" complicating Hodgkin's disease: a case apparently caused by radiotherapy. JAMA 195: 488, 1966. CrossrefMedlineGoogle Scholar4. WHITAKERBREWERFITZGERALDHEATH WDMD: Clinical pathologic conference. Takayashu's syndrome; Hodgkin's disease. Amer. Heart J. 68: 549, 1964. CrossrefMedlineGoogle Scholar5. AUSTENBLENNERHASSETT WGJB: Giantcell aortitis causing an aneurysm of the ascending aorta and aortic regurgitation. New Eng. J. Med. 272: 80, 1965. CrossrefMedlineGoogle Scholar6. JUDGECURRIERGRACIEFIGLEY RDRDWAMM: Takayasu's arteritis and the aortic arch syndrome. Amer. J. Med. 32: 379, 1962. CrossrefMedlineGoogle Scholar7. HEGGTVEITHENNIGARMORRIONE HAGRTG: Panaortitis. Amer. J. Path. 42: 151, 1963. MedlineGoogle Scholar8. ROTHKISSANE LMJM: Panaortitis and aortic valvulitis in progressive systemic sclerosis (scleroderma). Amer. J. Clin. Path. 41: 287, 1964. CrossrefMedlineGoogle Scholar9. MILLER DG: The association of immune disease and malignant lymphoma. Ann. Intern. Med. 66: 507, 1967. LinkGoogle Scholar10. DOLLINGERLAVINEFOYE MRDMLV: Myocardial infarction due to postirradiation fibrosis of the coronary arteries. Case of successfully treated Hodgkin's disease with lower esophageal involvement. JAMA 195: 316, 1966. CrossrefMedlineGoogle Scholar11. COHNSTEWARTFAJARDOHANCOCK KEJRLFEW: Heart disease following radiation. Medicine (Bait.) 46: 281, 1967. CrossrefMedlineGoogle Scholar12. MARCIAL-ROJASCASTRO RAJR: Irradiation injury to elastic arteries in the course of treatment for neoplastic disease. Ann. Otol. 71: 945, 1962. Google Scholar13. ASK-UPMARKFAJERS ECM: Further observations on Takayashu's syndrome. Acta Med. Scand. 155: 275, 1956. CrossrefMedlineGoogle Scholar14. GUTTMANBAILEY PHDW: Potentiating effect of neonatal thymectomy on x-ray-induced intercapillary glomerulosclerosis. Nature (London) 207: 539, 1965. CrossrefMedlineGoogle Scholar15. DEEPFRAUMENITASHIMAMCDIVITT WDJFCKR: Leukoencephalopathy and dermatomyositis in Hodgkin's disease. A case report. Arch. Intern. Med. (Chicago) 113: 635, 1964. CrossrefMedlineGoogle Scholar16. LEWISSCHWARTZDAMESHEK FBRSW: X-radiation and alkylating agents as possible "trigger" mechanisms in the autoimmune complications of malignant lymphoproliferative disease. Clin. Exp. Immun. 1: 3, 1966. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Bethesda, Maryland, and St. Louis, MissouriFrom the Epidemiology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Md., and the Departments of Pediatrics and Pathology, St. Louis Children's Hospital and Washington University School of Medicine, St. Louis, Mo.Requests for reprints should be addressed to Joseph F. Fraumeni, Jr., M.D., 410 Wiscon Bldg., National Institutes of Health, Bethesda, Md. 20014. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByHeartRadiation-induced Vascular InjuriesArteriotracheal Fistula in Patients Treated for LymphomaRadiation-induced chronic arterial injuryRupture of major vessels after radiationFatal Foam Cell Arteritis of the Brain After Irradiation for Hodgkin's Disease: Angiography and PathologyAneurysm of the descending thoracic aorta, amyloidosis and renal carcinoma in a patient with ankylosing spondylitis 1 December 1967Volume 67, Issue 6Page: 1242-1248KeywordsAortaCancer epidemiologyChild healthChildrenEtiologyHodgkin lymphomaHospital medicineLymphomaPediatricsRadiation therapy Issue Published: 1 December 1967 PDF DownloadLoading ...