Mast Cells in the Skin: Progressive Systemic Sclerosis and the Toxic Oil Syndrome
Authors: EDUARDO FONSECA
Journal: Annals of Internal Medicine (1985)

Letters and Corrections1 June 1985Mast Cells in the Skin: Progressive Systemic Sclerosis and the Toxic Oil SyndromeEDUARDO FONSECA, M.D., JAVIER SOLÍS, M.D.EDUARDO FONSECA, M.D.Search for more papers by this author, JAVIER SOLÍS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-102-6-864_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Hawkins and coworkers (1) showed a specific increase in the number of mast cells in clinically affected skin of patients with the early indurative stage of progressive systemic sclerosis. We have studied mast cells in the skin of patients with different stages of the toxic oil syndrome. This syndrome, which has a marked similarity to progressive systemic sclerosis, appeared as an epidemic in Spain in 1981.Some 22 000 persons were affected by this syndrome, having acute fever, cough, blood, eosinophilia, cutaneous exanthema, pruritus, myalgia, arthralgia, headache, noncardiogenic pulmonary edema, and gastrointestinal symptoms. From the second month...References1. HAWKINSCLAMANCLARKSTEIGERWALD RHRJ. Increased dermal mast cell populations in progressive systemic sclerosis: a link in chronic fibrosis? Ann Intern Med. 1985;102:182-6. LinkGoogle Scholar2. NORIEGAGÓMEZ-REINOLÓPEZ AJA. Toxic epidemic syndrome, Spain, 1981. Lancet. 1982;2:697-702. MedlineGoogle Scholar3. MARTÍNEZ-TELLONAVAS PALACIOSRICOY FJR. Pathology of a new toxic syndrome caused by ingestion of adulterated oil in Spain. Virchows Arch [A]. 1982;397:261-85. CrossrefMedlineGoogle Scholar4. RIGAU-PÉREZ J. Summary of case-control studies and case or cluster investigations. In: Toxic Oil Syndrome: Mass Food Poisoning in Spain. Geneva: World Health Organization; 1984:47-51. Google Scholar5. FONSECA E. Manifestaciones cutáneas del Síndrome Tóxico por aceite de colza adulterado. Actas Dermo-Sifiliogr. 1983;10:297-316. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byMast Cells in Angiogenesis: The Role of Angiogenic CytokinesMast cells in human digestive tube in normal and pathological conditionsManifestaciones cutáneas del síndrome tóxico por aceite de colza adulteradoSkin Manifestations of Toxic Syndrome Due to Denatured Rapeseed OilEosinophilia–Myalgia Syndrome and Eosinophilic Fasciitis (Shulman Syndrome)Activity of certain drugs in inducing of inflammatory myopathies with cutaneous manifestationsMast Cells: Not Only in AllergyChemically Induced SclerodermaL-tryptophan syndrome: histologic features of scleroderma-like skin changesThe Toxic PseudosclerodermasL-Tryptophan-Associated Eosinophilia-Myalgia Syndrome: Perspective of a New IllnessCutaneous manifestations of the L-tryptophan-associated eosinophilia-myalgia syndrome: A spectrum of sclerodermatous skin diseaseDermal mast cell degranulation in systemic sclerosisMyocardial mast cells in systemic sclerosis: A report of three fatal casesMast Cells and FibrosisAnti-IgE autoantibodies in systemic sclerosis (scleroderma).Cutaneous mucinosis in the toxic oil syndrome 1 June 1985Volume 102, Issue 6Page: 864-865KeywordsBloodEdemaEosinophiliaFeversHeadachesMast cellsMyalgiaOilsPruritusScleroderma Issue Published: 1 June 1985 PDF downloadLoading ...