The Output of Protein After Pancreozymin
Authors: DONALD H. HANSCOM
Journal: Annals of Internal Medicine (1967)

Article1 April 1967The Output of Protein After PancreozyminA Test of Pancreatic FunctionDONALD H. HANSCOM, M.D., BURTON M. JACOBSON, M.D., ARMAND LITTMAN, M.D., PH.D., F.A.C.P.DONALD H. HANSCOM, M.D.Search for more papers by this author, BURTON M. JACOBSON, M.D.Search for more papers by this author, ARMAND LITTMAN, M.D., PH.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-66-4-721 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe secretin test has become well established for the diagnosis of pancreatic disease (1), but it may not be helpful when the disease is of limited extent or severity (2). It was hoped that pancreozymin preparations, as a stimulant to enzyme output, would add to the diagnostic value of secretin. This hope has not thus far been fulfilled.Increasing the dose of pancreozymin progressively improved the differentiation of normal from abnormal responses (3), but the dose-response relationship was linear only when initial doses were excluded; that is, responses to initial doses of pancreozymin were more variable than to subsequent doses....References1. DREILINGJANOWITZ DAHD: The measurement of pancreatic secretory function, in Ciba Foundation Symposium on the Exocrine Pancreas. Little, Brown & Co., Boston, 1961, p. 225. Google Scholar2. FRIEDMANSNAPE MHWJ: Dissociation of secretion of pancreatic enzymes and bicarbonate in patients with chronic pancreatitis. Gastroenterology 15: 296, 1950. CrossrefMedlineGoogle Scholar3. HANSCOMLITTMAN DHA: Dose-response relationships to pancreozymin in normal subjects and patients with chronic pancreatitis. Gastroenterology 45: 209, 1963. CrossrefMedlineGoogle Scholar4. SARLES H: Pancreatitis, Symposium Marseilles. S. Karger, Basel, 1965, p. VII. Google Scholar5. KOLMERSPAULDINGROBINSON JAEHHW: Approved Laboratory Technic, 5th ed. Appleton-Century-Crofts, New York, 1951, p. 272. Google Scholar6. KAPLANEDIDINFRUINBAKER EBRCL: Intestinal absorption of iodine-131-labeled triolein and oleic acid in normal subjects and in steatorrhea. Gastroenterology 34: 901, 1958. CrossrefMedlineGoogle Scholar7. HERRERA L: The precision of percentiles in establishing normal limits in medicine. J. Lab. Clin. Med. 52: 34, 1958. MedlineGoogle Scholar8. KENDALLSTUART MGA: The Advanced Theory of Statistics. Hafner Publishing Co., New York, 1966, p. 314. Google Scholar9. JORPESMUTT JEV: Personal communication. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Hines and Chicago, IllinoisFrom the Medical Service, Veterans Administration Hospital, Hines, and the Departments of Medicine, University of Illinois College of Medicine, Chicago, and the Stritch School of Medicine, Loyola University, Hines, Ill.This paper was presented in part at the Second Fall Meeting of the American College of Physicians, Los Angeles, Calif., October 9, 1964.Requests for reprints should be addressed to Donald H. Hanscom, M.D., Veterans Administration Hospital, Hines, Ill. 60141. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byA simple assay technique for pancreatic lipaseNeurohormonal control of pancreatic secretionTests of Exocrine Pancreatic FunctionChronic pancreatitis in African diabeticsSecretin and Cholecystokinin (CCK)Testing Pancreatic FunctionDiagnostic Biochemical Methods in Pancreatic DiseaseDiagnostic Tests in Pancreatic Disease 1 April 1967Volume 66, Issue 4Page: 721-726KeywordsBiostatisticsEnzymesFallsHospital medicineMedical servicesPancreatic diseasesPancreatitisProteinsSecretin Issue Published: 1 April 1967 PDF downloadLoading ...