On the Pathogenesis of Diabetic Steatorrhea
Authors: S. M. SUMI
Journal: Annals of Internal Medicine (1961)

Case Reports1 December 1961On the Pathogenesis of Diabetic SteatorrheaS. M. SUMI, M.D., J. M. FINLAY, M.D., F.R.C.P. (C), F.A.C.P.S. M. SUMI, M.D.Search for more papers by this author, J. M. FINLAY, M.D., F.R.C.P. (C), F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-55-6-994 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe systemic complications of diabetes mellitus have been well described in the past (1). Intermittent, continuous, or nocturnal diarrhea, and nocturnal fecal incontinence have been noted frequently (1-4), and usually have been related to autonomic nervous system disorder. The complication of steatorrhea has had much less attention until recently.Many etiological factors have been suggested to explain these gastrointestinal findings in the past. Vitamin deficiency, particularly of the B group, has been suggested by some (3), based on their success in treatment of the condition with vitamin B12and liver extract. It is generally agreed that deficiency of external pancreatic...References1. RUNDLES RW: Diabetic neuropathy. Medicine 24: 11, 1945. CrossrefGoogle Scholar2. BARGENBOLLMANKEPLER JAHLEJ: The diarrhea of diabetes and steatorrhea of pancreatic origin. Proc. Mayo Clin. 11: 737, 1936. Google Scholar3. SHERIDANBAILEY EPCC: Diabetic nocturnal diarrhea. J. A. M. A. 130: 632, 1946. CrossrefMedlineGoogle Scholar4. MALINSFRENCH JMJM: Diabetic diarrhea. Quart. J. Med. 36: 467, 1957. Google Scholar5. BERGEWOLLAEGERSCHOLZROOKESPRAGUE KGEEDAEDRG: Steatorrhea complicating diabetes mellitus with neuropathy. Diabetes 5: 25, 1956. CrossrefMedlineGoogle Scholar6. AKTANKLOTZ HSAP: Fat absorption and pancreatic function in diabetes mellitus. Ann. Intern. Med. 49: 820, 1958. LinkGoogle Scholar7. HODGESRUNDLESHAMELIN FJRWJ: Roentgenologic study of the small intestine. II. Dysfunction associated with neurologic diseases. Radiology 49: 659, 1947. CrossrefMedlineGoogle Scholar8. KASSANDERS P: Asymptomatic gastric retention in diabetes: gastroparesis diabeticorum. Ann. Intern. Med. 48: 797, 1958. LinkGoogle Scholar9. COHEN WC: Severe diabetic neuropathy: a case study with special reference to the autonomic nervous system. Diabetes 8: 63, 1959. CrossrefMedlineGoogle Scholar10. TAXAYROATHMITCHEL EPSS: Malabsorption syndrome and diabetes mellitus. Diabetes 9: 106, 1960. CrossrefMedlineGoogle Scholar11. VAN DE KAMERTEN BOKKEL HUININKWEYERS JHHHA: Rapid method for the determination of fat in feces. J. Biol. Chem. 177: 347, 1949. CrossrefMedlineGoogle Scholar12. FINLAYWIGHTMAN JMKJ: The xylose tolerance test as a measure of the intestinal absorption of carbohydrate in sprue. Ann. Intern. Med. 49: 1332, 1958. LinkGoogle Scholar13. FRAZER AC: A new mechanism of vitamin deprivation. Brit. Med. J. 2: 731, 1949. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Toronto,This study was supported by grants from the National Research Council of Canada.Requests for reprints should be addressed to John M. Finlay, M.D., Suite 430, Medical Arts Building, Toronto 5, Ontario, Canada. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByFecal excretions of hydroxy fatty acid and bile acid in diabetic diarrheal patientsGastrointestinal Complications of Diabetes MellitusDisorders of Gastrointestinal Motility Associated with Diabetes MellitusMARK FELDMAN, M.D., LAWRENCE R. SCHILLER, M.D.Bakterienflora des DünndarmsPathogenesis of Fecal Incontinence in Diabetes MellitusPancreatic DiseasesDiabetes and the gut.Bile Salt Metabolism:II. Bile Salts and DiseaseDie diabetische NeuropathieThe small intestine in diabetes mellitus. Correlation of clinical phenomena to histomorphometric findings in peroral biopsy materialNeuropatía Diabética VisceralVAGAL FUNCTION IN PATIENTS WITH DIABETIC NEUROPATHYIntestinal MicrofloraDiabetic Diarrhea and Steatorrhea Microbiologic and Clinical ObservationsFRANZ GOLDSTEIN, M.D., F.A.C.P., C. W. WIRTS, M.D., F.A.C.P., O. DHODANAND KOWLESSAR, M.D.Diabetic DiarrheaThe effect of methotrexate on rabbit intestinal mucosal enzymes and floraDiabetes and SteatorrhoeaMalabsorptionA Clinical Evaluation of the D-Xylose Tolerance TestJOHN M. FINLAY, M.D., F.R.C.P. (C), F.A.C.P., JEAN HOGARTH, M.D., F.R.C.P. (C), KEITH J. R. WIGHTMAN, M.D., F.R.C.P. (C), F.A.C.P.Diabetic steatorrhea: A distinct entityMalabsorptionMalabsorption and the Diarrhea of Diabetes Mellitus 1 December 1961Volume 55, Issue 6Page: 994-997KeywordsDiabetes mellitusDiarrheaExcretionHematologic testsHypotensionIncontinenceInsulinLiverPathogenesisPathogens Issue Published: 1 December 1961 PDF DownloadLoading ...