Epidemiologic Relation between HIV and Invasive Pneumococcal Disease in San Francisco County, California
Authors: Immaculada Grau, Josefina Liñares, Roman Pallares
Journal: Annals of Internal Medicine (2000)

Letters20 June 2000Epidemiologic Relation between HIV and Invasive Pneumococcal Disease in San Francisco County, CaliforniaImmaculada Grau, MD, Josefina Liñares, MD, and Roman Pallares, MDImmaculada Grau, MDUniversity of Barcelona; 08907 Barcelona, Spain (Grau)University of Barcelona; 08907 Barcelona, Spain (Liñares)University of Barcelona; 08907 Barcelona, Spain (Pallares)Search for more papers by this author, Josefina Liñares, MDUniversity of Barcelona; 08907 Barcelona, Spain (Grau)University of Barcelona; 08907 Barcelona, Spain (Liñares)University of Barcelona; 08907 Barcelona, Spain (Pallares)Search for more papers by this author, and Roman Pallares, MDUniversity of Barcelona; 08907 Barcelona, Spain (Grau)University of Barcelona; 08907 Barcelona, Spain (Liñares)University of Barcelona; 08907 Barcelona, Spain (Pallares)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-132-12-200006200-00032 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Nuorti and colleagues (1) reported on the epidemiology of invasive pneumococcal disease in HIV-infected patients in San Francisco. They found that this population had a high incidence of invasive pneumococcal infections. Even more important, they observed a significant reduction in pneumococcal disease among patients with AIDS, probably as a result of the wider use of highly active antiretroviral therapy.In our institution, we noted a significant reduction in the number of HIV-infected patients among all patients with bacteremic pneumococcal infections: 38 of 198 (19.2%) in 1994–1996 and 25 of 224 (11.2%) in 1997–1999 (P = 0.02). As occurred ...References1. Nuorti JK, Butler JC, Gelling L, Kool JL, Reingold AL, Vugia DJ. Epidemiologic relation between HIV and invasive pneumococcal disease in San Francisco County, California. Ann Intern Med. 2000;132:182-90. LinkGoogle Scholar2. Pallares R, Liñares J, Vadillo M, Cabellos C, Manresa F, Viladrich PF, et al . Resistance to penicillin and cephalosporin and mortality from severe pneumococcal pneumonia in Barcelona, Spain. N Engl J Med. 1995;333:474-80. CrossrefMedlineGoogle Scholar3. John P, Kimari J, Gilks CF. Streptococcus pneumoniae resistant to penicillin and tetracycline associated with HIV seropositivity. Lancet. 1995;346:1034-5. CrossrefGoogle Scholar4. Breiman RF, Butler JC, Tenover FC, Elliot JA, Facklam RR. Emergence of drug-resistant pneumococcal infections in the United States. JAMA. 1994;271:1831-5. CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: University of Barcelona; 08907 Barcelona, Spain (Grau)University of Barcelona; 08907 Barcelona, Spain (Liñares)University of Barcelona; 08907 Barcelona, Spain (Pallares) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoEpidemiologic Relation between HIV and Invasive Pneumococcal Disease in San Francisco County, California J. Pekka Nuorti , Jay C. Butler , Lisa Gelling , Jacob L. Kool , Arthur L. Reingold , and Duc J. Vugia Epidemiologic Relation between HIV and Invasive Pneumococcal Disease in San Francisco County, California Mark S. Dworkin and Debra L. Hanson Metrics 20 June 2000Volume 132, Issue 12Page: 1009KeywordsAIDSDeath ratesEpidemiologyHIV epidemiologyHIV infectionsHighly active antiretroviral therapyInfectious diseasesPenicillinResearch designVaccines Issue Published: 20 June 2000 Copyright & PermissionsCopyright © 2000 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...