25 Years and Counting: Centers for Disease Control and Prevention Identifies Opportunities and Challenges for Diabetes Prevention and Control
Authors: Frank Vinicor, Leonard Jack
Journal: Annals of Internal Medicine (2004)

Supplement: Diabetes Translation and Public Health: 25 Years of CDC Research and Programs1 June 200425 Years and Counting: Centers for Disease Control and Prevention Identifies Opportunities and Challenges for Diabetes Prevention and ControlFREEFrank Vinicor, MD, MPH and Leonard Jack Jr., PhD, MScFrank Vinicor, MD, MPHFrom the Centers for Disease Control Prevention, Atlanta, GA 30341-4002.Search for more papers by this author and Leonard Jack Jr., PhD, MScFrom the Centers for Disease Control Prevention, Atlanta, GA 30341-4002.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-140-11-200406010-00034 SectionsAboutVisual AbstractPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail The number of persons with diabetes, especially type 2 diabetes, has increased dramatically worldwide (1, 2) and is expected to grow substantially over the next several decades (3). This increased burden places more responsibility on patients, health care professionals, and society. Diabetes has always been a challenge to manage (4). Despite recent scientific advances in our understanding of its pathophysiology (5), awareness of the many factors that affect its care (6), and improved treatment options (7), diabetes still remains a complex and challenging chronic condition. Diabetes is more than merely abnormal glucose metabolism with consequent microvascular complications (8); it also involves cardiovascular disease with adverse macrovascular outcomes (9). Furthermore, recent studies have established a possible bicausal relationship between diabetes and depression (10, 11), thus supporting the link between this condition and psychological functioning.Recognizing and incorporating the role these various factors play in the prevention and control of diabetes move us beyond solely “treating” diabetes with drugs (12). This progress offers opportunities to complement effective diabetes management with a public health approach that considers availability of medical insurance (13, 14), community resources (15), family structure and support (16), and effective health communications that include advice about risk reduction and cues to action (17).During the past 25 years, the Division of Diabetes Translation at the Centers for Disease Control and Prevention (CDC) has depended on available scientific findings to guide its public health programs. From 1979 through the early 1990s, the CDC focused on tertiary prevention, such as screening and treatment for diabetic retinopathy (18) and preventing the development of diabetic foot disorders and amputations (19). During this same period, most diabetes public health programs, including those supported by the CDC, provided actual clinical care for people who cannot participate in private health care systems. In 1993 and 1994, the CDC altered both the content and the methods of its public health programs. Because of the important Diabetes Control and Complication Trial (20), secondary prevention—that is, glycemic control—was added to existing tertiary prevention strategies. Furthermore, although there was (and still is) a need to assist individuals who are underinsured or uninsured, the CDC recognized that it was not applying its public health strategy for all people with diabetes in the United States. Consequently, primarily through its state-based Diabetes Prevention and Control Programs (21), the CDC began to develop a “model of influence,” or system-based, approach that involves national, regional, and local partners in ensuring adoption of the health care, community, organizational, and public policy systems—changes that ultimately would help improve the delivery and sustainability of good-quality diabetes care for everyone affected (22, 23). While the CDC's “model of influence” approach to diabetes programs has continued, diabetes science also has progressed, resulting in the addition of cardiovascular disease prevention initiatives among patients with diabetes (9), as well as primary prevention of type 2 diabetes among those at high risk for developing this disease (24).This supplement provides 6 original papers based on presentations shared at the CDC's “Diabetes and Public Health 25th Anniversary Symposium” held in September 2003 in Atlanta, Georgia. Articles address the evolution of the diabetes epidemic in the United States, primary prevention of type 2 diabetes, translational research, environmental issues in diabetes self-management, analysis of the economic impact of diabetes, and the CDC's efforts to use findings from important clinical studies to establish public health programs within the national NDPC program.Engelgau and associates describe the evolution of the diabetes epidemic and the burden imposed by diabetes complications in the United States. They discuss the prevalence and incidence of diabetes among adults, as well as the increasing burden of diabetes among children and adolescents. This article concludes by briefly discussing the major risk factors for diabetes-related complications, diabetes-related mortality, future projections of the burden of diabetes into the 21st century, and a rationale for including primary prevention in future diabetes programs.The CDC Primary Prevention Working Group summarizes the scientific evidence supporting lifestyle interventions to prevent type 2 diabetes. The group emphasizes the importance of consensus in 4 policy areas: identification of persons needing interventions, integration of lifestyle interventions into medical care systems, economic considerations, and ethical implications.Narayan and colleagues discuss the challenge of extending the results of numerous studies that had shown efficacy of diabetes treatments into actual clinical practice, an extension still slowly progressing and inadequate in reach. This article provides examples of interventions that, through translational efforts, allow providers, health systems, and patients to improve diabetes care. The authors conclude by briefly discussing the critical importance of maintaining a multidisciplinary perspective in translational research.Jack and colleagues qualitatively reviewed 8 studies that contained sufficient evidence to show that including diabetes self-management education in community settings can improve glycemic control. The authors emphasize the important dimensions of specifications of theory, cultural appropriateness of interventions, and use of quality instruments to capture intervention effects.Zhang and associates address the growing importance of economic analyses to help health care providers and policymakers determine the most appropriate use of scarce resources. They identify the financial impact that diabetes exacts on the health care system and the economic cost of diabetes in the United States. They discuss economic methods for evaluating an intervention in health and medicine, as well as cost–utility or cost–benefit ratios of interventions for preventing and treating diabetes. The authors also describe future directions for economic research.This supplement concludes with a timely and appropriate discussion of the CDC's National Diabetes Prevention and Control Program, the cornerstone of public health efforts to reduce the burden of diabetes in the United States. Murphy and colleagues provide a rationale for this national program's use of system-based interventions that consider moderating factors such as intervention settings, population characteristics, and financial and human resource constraints on diabetes prevention and control.In summary, although we know more about how to prevent and control diabetes and its complications today then we did 25 years ago, the threat of diabetes to individuals, families, communities, and society is still a major—and growing—concern. To fully translate this important knowledge, efforts in the physician's office need to be complemented by effective public health interventions where people live, work, and play. Collaborative partnerships with persons given a diagnosis of diabetes, purchasers, and payers of health care services, policymakers, and political decision makers are essential in this process. Because of our quarter-century of experience in public health, the CDC is well positioned to apply the best available evidence and practices from both the clinical and public health worlds to combat the growing burden of diabetes in the United States and throughout the world.References1. Soltesz G. Diabetes in the young: a paediatric and epidemiologic perspective. Diabetologia. 2003;46:447-54. CrossrefMedlineGoogle Scholar2. Zimmet P. Globalization, coca-colonization and the chronic disease epidemic: can the Doomsday scenario be averted? J Intern Med. 2000;247:301-10. [PMID: 10762445] CrossrefMedlineGoogle Scholar3. 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Problems paying out-of-pocket medication costs among older adults with diabetes. Diabetes Care. 2004;27:384-91. [PMID: 14747218] CrossrefMedlineGoogle Scholar15. Pretty J. Social capital and the collective management of resources. Science. 2003;302:1912-4. [PMID: 14671287] CrossrefMedlineGoogle Scholar16. Fisher L, Weihs KL. Can addressing family relationships improve outcomes in chronic disease? Report of the National Working Group on Family-Based Interventions in Chronic Disease. J Fam Pract. 2000;49:561-6. [PMID: 10923558] MedlineGoogle Scholar17. Jack L, Sokler LA, Squiers L, Mitchell P. The National Diabetes, Influenza, and Pneumococcal Campaign: an evaluation of campaign relevancy, partnerships, and media relations. J Public Health Manag Pract. 2003;Suppl:S64-9. [PMID: 14677333] CrossrefMedlineGoogle Scholar18. Fong DS, Aiello L, Gardner TW, King GL, Blankenship G, Cavallerano JD, et al . Diabetic retinopathy. Diabetes Care. 2003;26:226-9. [PMID: 12502685] CrossrefMedlineGoogle Scholar19. Valk GD, Kriegsman DM, Assendelft WJ. Patient education for preventing diabetic foot ulceration. Cochrane Database Syst Rev. 2001:CD001488. [PMID: 11687114] MedlineGoogle Scholar20. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group. N Engl J Med. 1993;329:977-86. [PMID: 8366922] CrossrefMedlineGoogle Scholar21. Safran MA, Mukhtar Q, Murphy DL. Implementing program evaluation and accountability for population health: progress of a national diabetes control effort. J Public Health Manag Pract. 2003;9:58-65. [PMID: 12552931] CrossrefMedlineGoogle Scholar22. Institute of Medicine. Crossing the Quality Chasm: A New Health Care System for the 21st Century. Washington, DC: National Academy of Science Pr; 2001. Google Scholar23. Berwick DM. Disseminating innovations in health care. 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[PMID: 12598137] CrossrefMedlineGoogle Scholar Comments0 CommentsSign In to Submit A Comment Author, Article, and Disclosure InformationAffiliations: From the Centers for Disease Control Prevention, Atlanta, GA 30341-4002.Disclosures: None disclosed.Corresponding Author: Frank Vinicor, MD, MPH, Division of Diabetes Translation, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Woodcock Boulevard, Room 2044, Atlanta, GA 30341-4002; e-mail, [email protected]gov.Current Author Addresses: Dr. Vinicor: Division of Diabetes Translation, National Center for Chronic Disease Prevention, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Woodcock Boulevard, Room 2044, Atlanta, GA 30341-4002Dr. Jack: Community Intervention Section, Program Development Branch, Division of Diabetes Translation, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Woodcock Boulevard, Room 1062, Atlanta, GA 30341-4002. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byTang Wang Ming Mu Granule Attenuates Diabetic Retinopathy in Type 2 Diabetes RatsEfficacy and immunogenicity of recombinant swinepox virus expressing the truncated S protein of a novel isolate of porcine epidemic diarrhea virusType 2 Diabetes Mellitus in Children and Adolescents: Early Prevention and Non-Drug TherapyChildhood type 2 diabetes: Risks and complicationsEfficacy and immunogenicity of recombinant swinepox virus expressing the A epitope of the TGEV S proteinThe Wrong Tool for the Job: Diabetes Public Health Programs and Practice GuidelinesPublic health aspects of diabetes mellitus – epidemiology, prevention strategies, policy implications: the first Austrian diabetes report 1 June 2004Volume 140, Issue 11Page: 943-944KeywordsCardiovascular diseasesDiabetes preventionForecastingHealth careHealth care providersHealth economicsHealth insuranceHealth promotionPrevention, policy, and public healthType 2 diabetes ePublished: 1 June 2004 Issue Published: 1 June 2004 PDF downloadLoading ...