Pancreatic Carcinoma as a Cause of Unexplained Pancreatitis: Report of Ten Cases
Authors: Albert Lin
Journal: Annals of Internal Medicine (1990)

Brief Reports15 July 1990Pancreatic Carcinoma as a Cause of Unexplained Pancreatitis: Report of Ten CasesAlbert Lin, MDMPH, Edward R. Feller, MDAlbert Lin, MDMPH, Edward R. Feller, MDAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-113-2-166 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptWe studied ten patients with documented pancreatic carcinoma who initially presented with acute onset of abdominal pain and hyperamylasemia typical of acute pancreatitis. We report this unusual association of these common diseases to alert clinicians to consider underlying carcinoma in unexplained acute pancreatitis.Patients and MethodsRecords from March 1978 to December 1987 of patients with pancreatic carcinoma were reviewed retrospectively in two hospitals affiliated with Brown University. Ten patients (3.0% of 302 patients with pancreatic carcinoma; 95% confidence interval [CI], 2.01% to 3.99%) were identified in whom acute pancreatitis was the initial clinical feature of a subsequently proven pancreatic...References1. Gambill E. Pancreatitis associated with pancreatic carcinoma: a study of 26 cases. Mayo Clin Proc. 1971;46:174-7. MedlineGoogle Scholar2. WilsonImrie CC. Occult pancreatic cancer with recurrent acute pancreatitis. Postgrad Med J. 1986;62:765-7. CrossrefMedlineGoogle Scholar3. KohlerLankisch HP. Acute pancreatitis and hyperamylasemia in pancreatic carcinoma. Pancreas. 1987;2:117-9. CrossrefMedlineGoogle Scholar4. McLatchieImrie GC. Acute pancreatitis associated with tumour metastases in the pancreas. Digestion. 1981;21:13-7. CrossrefMedlineGoogle Scholar5. AllanTournutWhite BRT. Intraductal activation of pancreatic zymogen behind a carcinoma of the pancreas. Gastroenterology. 1973;65:412-8. CrossrefMedlineGoogle Scholar6. HowardWagner JS. Pancreatography after recovery from massive pancreatic necrosis. Ann Surg. 1989;209:31-5. CrossrefMedlineGoogle Scholar7. LaugierCamatteSarles RRH. Chronic obstructive pancreatitis after healing of a necrotic pseudocyst. Am J Surg. 1983;146:551-7. CrossrefMedlineGoogle Scholar8. Feller E. Stenosis of the main pancreatic duct in acute pancreatitis of unknown etiology. Gastrointest Endosc. 198834:131-3. Google Scholar9. RohrmannSilvisVenues CSJ. The significance of pancreatic ductal obstruction in differential diagnosis of the abnormal endoscopic retrograde pancreatogram. Radiology. 1976;121:311-4. CrossrefMedlineGoogle Scholar10. RallsHallsJuttner PJH. Endoscopic retrograde cholangiopancreatography (ERCP) in pancreatic disease: a reassessment of the specificity of ductal abnormalities in differentiating benign from malignant disease. Radiology. 1980;134:347-52. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: From Memorial Hospital, Pawtucket, Rhode Island; Miriam Hospital, Providence, Rhode Island; and Brown University, Providence, Rhode Island. For current author addresses, see end of text. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByIdiopathic acute pancreatitis—A myth or reality? 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