Neutrophilic Leukemia and Blastic Crisis
Authors: TETSURO SHINDO
Journal: Annals of Internal Medicine (1977)

Brief Reports1 July 1977Neutrophilic Leukemia and Blastic CrisisTETSURO SHINDO, M.D., CHIKARA SAKAI, M.D., AKIRA SHIBATA, M.D.TETSURO SHINDO, M.D., CHIKARA SAKAI, M.D., AKIRA SHIBATA, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-87-1-66 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptNeutrophilic leukemia is characterized by leukocytosis with mature neutrophils in peripheral blood, absense of Ph′ chromosome, and elevated neutrophil alkaline phosphatase activity (1-4). Because it is occasionally difficult to rule out the leukemoid reaction, its disease entity is unestablished yet. To our knowledge, this is the first such case terminating in blastic crisis.A 74-year-old man consulted a doctor with the complaint of impaired vision in January 1975. A diagnosis of senile cataract was made but he was found in leukocytosis and hepatosplenomegaly. He was subjectively so well that no specific treatment was done, and the course was observed as...References1. TANZERHARELBOIRONBERNARD JPMJ: Cytochemical and cytogenetic findings in a case of chronic neutrophilic leukaemia of mature cell type (letter). Lancet 1:387-388, 1964 CrossrefMedlineGoogle Scholar2. JACKSONCLARK IR: A case of neutrophilic leukemia. Am J Med Sci 249:72-74, 1965 CrossrefMedlineGoogle Scholar3. RUBIN H: Chronic neutrophilic leukemia. Ann Intern Med 65: 93-100, 1966 LinkGoogle Scholar4. SILBERSTEINZELLNERSHIVAKUMARBURGIN EDBL: Neutrophilic leukemia (letter). Ann Intern Med 80:110, 1974 LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: TETSURO SHINDO, M.D.; CHIKARA SAKAI, M.D.; AKIRA SHIBATA, M.D.Affiliations: Third Department of Internal Medicine Akita University School of Medicine Akita Japan PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAcquired gain of an X chromosome as the sole abnormality in the blast crisis of chronic neutrophilic leukemiaCHRONIC NEUTROPHILIC LEUKAEMIA: A DISTINCT CLINICAL ENTITY?Serum G-CSF Levels in Primary Myelofibrosis and Chronic Neutrophilic Leukemia as Estimated by the Highly Sensitive Chemiluminescence Enzyme Immunoassay (CLEIA)Chronic neutrophilic leukemiaLevels of Serum Granulocyte Colony-Stimulating Factor in Patients with Chronic Myeloid LeukemiaElevated neutrophil function in chronic neutrophilic leukemiaChronic neutrophilic leukemia with marked myelodysplasia terminating in blast crisisLymph node involvement in chronic neutrophilic leukemiaHaematological classification of the chronic myeloid leukaemiasNeutrophilic leukemia accompanied by hemorrhagic diathesis: Report of two casesCytobiologic and clinical aspects in a patient with chronic neutrophilic leukemia after thorotrast exposureChronic neutrophilic leukaemia with enlarged lymph nodes and lysozyme deficiencyFunctional characterization of the cells in chronic neutrophilic leukemiaCoexistent chronic myeloid leukemia and IgA monoclonal gammopathy: report of a case and review of the literature 1 July 1977Volume 87, Issue 1Page: 66-67KeywordsBloodChromosomesHepatosplenomegalyLeukemoidLeukocytosisNeutrophilsPhosphatasesVision ePublished: 1 December 2008 Issue Published: 1 July 1977 PDF downloadLoading ...