Significance of Alcohol-Induced Hypertriglyceridemia in Patients with Type IV Hyperlipoproteinemia
Authors: Jack H. Mendelson, Nancy K. Mello
Journal: Annals of Internal Medicine (1974)

Editorials1 February 1974Significance of Alcohol-Induced Hypertriglyceridemia in Patients with Type IV HyperlipoproteinemiaJACK H. MENDELSON, M.D., NANCY K. MELLO, PH.D.JACK H. MENDELSON, M.D.Search for more papers by this author, NANCY K. MELLO, PH.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-80-2-270 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe relation: between alcohol abuse and cardiac, pancreatic, and hepatic disease are still an enduring enigma in biomedical science. Two recent findings suggest that alcohol induces elevations in triglyceride levels that may in turn contribute to cardiac and gastrointestinal disorders in those individuals with a type IV hyperlipidemia (1, 2). The heuristic value of these findings is obvious in view of the high mortality associated with cardiac disease and the numerous medical complications of chronic alcohol abuse.Ginsberg and associates (2) report, on pages 143-149 of this issue, that even relatively small amounts of alcohol may increase plasma triglyceride levels...References1. MENDELSONMELLO JN: Alcohol-induced hyperlipidemia and beta lipoproteins. Science 180:1372-1374, 1973 CrossrefMedlineGoogle Scholar2. GINSBERGOLEFSKYFARQUHAR HJJ: Moderate ethanol ingestion and plasma triglyceride levels. A study in normal and hypertriglyceridemic persons. Ann Intern Med 80:143-149, 1974 LinkGoogle Scholar3. MELLO N: Behavioral studies of alcoholism, in The Biology of Alcoholism, vol. II, Physiology and Behavior, edited by KISSEN B, BEGLEITER H. New York, Plenum Publishing Corp., 1972, pp. 219-291 CrossrefGoogle Scholar4. MELLO N: Short-term memory function in alcohol addicts during intoxication, in Alcohol Intoxication and Withdrawal: Experimental Studies, edited by GROSS MM. New York, Plenum Publishing Corp., 1973 CrossrefGoogle Scholar5. MELLOMENDELSON NJ: Drinking patterns during work-contingent and non-contingent alcohol acquisition. Psychosom Med 34:139-164, 1972 CrossrefMedlineGoogle Scholar6. MENDELSON J (editor): Experimentally induced chronic intoxication and withdrawal in alcoholics. Q J Stud Alcohol (suppl 2):1-129, 1964 CrossrefMedlineGoogle Scholar7. TOBINDRISCOLLLIM JJM: Primary myocardial disease and alcoholism. The clinical manifestations and course of the disease in a selected population of patients observed for three or more years. Circulation 35:754-764, 1967 CrossrefMedlineGoogle Scholar8. PADER E: Clinical heart disease and electrocardiographic abnormalities in alcoholics. Q J Stud Alcohol 34:774-785, 1973 CrossrefMedlineGoogle Scholar9. LIEBER C: Alcohol and the liver, in The Biological Basis of Medicine, vol. V, edited by BITTAR EE. London, Academic Press Ltd., 1969, pp. 317-344 Google Scholar10. LIEBERRUBINDECARLI CEL: Chronic and acute effects of ethanol on hepatic metabolism of ethanol, lipids and drugs: correlation with ultrastructural changes, in Recent Advances in Studies of Alcoholism, edited by MELLO NK, MENDELSON JH. Washington, D.C., U.S. Government Printing Office, Publication No. (HSM) 71-9045, 1971 Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: JACK H. MENDELSON, M.D.; NANCY K. MELLO, PH.D.Affiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byEthanol and Lipid MetabolismEffects of alcohol on plasma lipoproteins and cholesterol and triglyceride metabolism in man.Effects of ethanol on lipid metabolism.Evaluation of Indices of Alcohol Intake in a Population of 60-Year-Old Men in Uppsala, SwedenDiabetes and the heart 1 February 1974Volume 80, Issue 2Page: 270-271KeywordsAlcoholismAlcoholsBlood plasmaHeart diseasesHyperlipidemiaMortality ePublished: 1 December 2008 Issue Published: 1 February 1974 PDF downloadLoading ...