Antileprosy Drugs and Lupus Erythematosus
Authors: JAMES T. JAKES
Journal: Annals of Internal Medicine (1982)

Letters and Corrections1 November 1982Antileprosy Drugs and Lupus ErythematosusJAMES T. JAKES, M.D., EDMUND L. DUBOIS, M.D., FRANCISCO P. QUISMORIO JR., M.D.JAMES T. JAKES, M.D.Search for more papers by this author, EDMUND L. DUBOIS, M.D.Search for more papers by this author, FRANCISCO P. QUISMORIO JR., M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-97-5-788_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: We read with interest the article describing the dramatic response to dapsone therapy of bullous eruptions in patients with systemic lupus erythematosus (1). We report our use of dapsone and another antileprosy drug, clofazimine, in an open trial for the treatment of mucocutaneous lesions in patients with systemic lupus erythematosus and discoid lupus erythematosus who were resistant to conventional antimalarial treatment or who needed continued systemic corticosteroid therapy. Clofazimine has been reported to be effective in the treatment of discoid lupus erythematosus (2, 3).Seven patients were given dapsone at a starting dose of 50 mg/d. This...References1. HALL R, LAWLEY T, SMITH H, and KATZ S. Bullous eruption of systemic lupus erythematosus: dramatic response to dapsone therapy. Ann Intern Med. 1982;97:165-70. LinkGoogle Scholar2. MACKEY J and BARNES J. Clofazimine in the treatment of discoid lupus erythematosus. Br J Dermatol. 1974;91:93-6. CrossrefMedlineGoogle Scholar3. MATTHEWS C, SAIHAN E, and WARIN R. Urticaria-like lesions associated with systemic lupus erythematosus: Response to dapsone. Br J Dermatol. 1978;99:555. CrossrefGoogle Scholar4. KRIVANEK J, PAVER W, and KOSSARD S. Clofazimine (Lamprene) in the treatment of discoid lupus erythematosus. Australas J Dermatol. 1976;17:108-10. CrossrefMedlineGoogle Scholar5. OGNIBENE A. Agranulocytosis due to dapsone. Ann Intern Med. 1970;72:521-4. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: JAMES T. JAKES, M.D.; EDMUND L. DUBOIS, M.D.; FRANCISCO P. QUISMORIOJR., M.D.Affiliations: University of Southern California School of Medicine Los Angeles, CA 90033 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byCutaneous Lupus ErythematosusSpecialized Treatment Approaches and Niche Therapies for Lupus SubsetsGastrointestinal Manifestations of Systemic Lupus ErythematosusGastrointestinalNONHEPATIC GASTROINTESTINAL MANIFESTATIONS OF SYSTEMIC LUPUS ERYTHEMATOSUSA review of gastrointestinal manifestations of systemic lupus erythematosusTREATMENT OF REFRACTORY CUTANEOUS LUPUS ERYTHEMATOSUSTreatment of Discoid Lupus ErythematosusNew Drugs for Dermatologic DiseasesAutofluorescence of clofazimine in discoid lupus erythematosusOral manifestations of lupus erythematosus 1 November 1982Volume 97, Issue 5Page: 788-788KeywordsAntimalarialsClofazimineCorticosteroid therapyDrug therapyLesionsLupus erythematosus ePublished: 1 December 2008 Issue Published: 1 November 1982 PDF downloadLoading ...