The Cushing Syndrome Associated with AIDS
Authors: Igor Tauveron
Journal: Annals of Internal Medicine (1994)

Letters1 April 1994The Cushing Syndrome Associated with AIDSIgor Tauveron, MD, Philippe Thieblot, MD, and Henri Laurichesse, MDIgor Tauveron, MDCentre Hospitalier Universitaire; F 63003 Clermont-Ferrand; FranceSearch for more papers by this author, Philippe Thieblot, MDCentre Hospitalier Universitaire; F 63003 Clermont-Ferrand; FranceSearch for more papers by this author, and Henri Laurichesse, MDCentre Hospitalier Universitaire; F 63003 Clermont-Ferrand; FranceSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-120-7-199404010-00021 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Although the adrenal is the endocrine gland most commonly involved in the acquired immunodeficiency syndrome (AIDS) [1], adrenal insufficiency is unusual [2]. Cortisol secretion in response to adrenocorticotropic hormone (ACTH) is generally normal or slightly impaired [2, 3]. Increased circadian plasma and 24-hour urinary free cortisol levels have been previously reported [2, 4, 5], but no patient had clinical symptoms of the Cushing syndrome. Further, Norbiato and colleagues' patients [5] showed Addisonian symptoms. In the latter case, hormonal changes (increased ACTH and cortisol and lack of suppression by dexamethasone) were attributed to peripheral cortisol resistance. We report ...References1. Grinspoon SK, Bilezikian JP. HIV disease and the endocrine system. N Engl J Med. 1992; 327:1360-5. Google Scholar2. Membreno I, Irony I, Dere W, Klein R, Biglieri EG, Cobb E. Adrenocortical function in acquired immunodeficiency syndrome. J Clin Endocrinol Metab. 1987; 65:482-7. Google Scholar3. Raffi F, Brisseau JM, Planchon B, Remi JP, Barrier JH, Grolleau JY. Endocrine function in 98 HIV-infected patients: a prospective study. AIDS. 1991; 5:729-33. Google Scholar4. Villette JM, Bourin P, Doinel C, Mansour I, Fiet J, Boudou P, et al. Circadian variations in plasma levels of hypophyseal, adrenocortical and testicular hormones in men infected with human immunodeficiency virus. J Clin Endocrinol Metab. 1990; 70:572-7. Google Scholar5. Norbiato G, Bevilacqua M, Vago T, Baldi G, Chebat E, Bertora P, et al. Cortisol resistance in acquired immunodeficiency syndrome. J Clin Endocrinol Metab. 1992; 74:608-13. Google Scholar Author, Article, and Disclosure InformationAuthors: Igor Tauveron, MD; Philippe Thieblot, MD; Henri Laurichesse, MDAffiliations: Centre Hospitalier Universitaire; F 63003 Clermont-Ferrand; France PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited by“Starve a fever and feed a cold”: feeding and anorexia may be adaptive behavioral modulators of autonomic and T helper balanceModulation of host immunity by HIV may be partly achieved through usurping host autonomic functionsExogenous Cushing Syndrome Mimicking Human Immunodeficiency Virus Lipodystrophy 1 April 1994Volume 120, Issue 7Page: 620-621KeywordsAdrenocorticotropic hormoneAIDSBlood plasmaCellsComputed axial tomographyCortisolHIV infectionsInterferonsThoraxTongue ePublished: 15 August 2000 Issue Published: 1 April 1994 Copyright & PermissionsCopyright © 1994 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...