Herpes Simplex Encephalitis: A Great Clinical Challenge
Authors: CARL B. LAUTER
Journal: Annals of Internal Medicine (1980)

Editorials1 May 1980Herpes Simplex Encephalitis: A Great Clinical ChallengeCARL B. LAUTER, M.D.CARL B. LAUTER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-92-5-696 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptHerpes simplex encephalitis is a much more important disease than its prevalence would otherwise indicate (1, 2). It carries a 70% to 80% mortality in the first 30 days and a 90% mortality by 4 to 6 months (3). Vidarabine, in a dosage of 15 mg/kg per day, given intravenously for 10 days, markedly improves the outcome if administered to the patient early in the course and before the occurrence of coma (2). Patients with herpes simplex encephalitis who are treated early have a mortality rate of 32% at 30 days and 41% by 4 months (3). Morbidity is also...References1. LERNERWILSONLAUTER AFC. 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LAUTER, M.D.Affiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDetection of Herpes Simplex Virus DNA in Cerebrospinal Fluid of Saudi Pediatric Patients with Encephalitis by the Polymerase Chain ReactionEEG and pathologic findings in patients undergoing brain biopsy for suspected encephalitisClinical Features: Disseminated InfectionSynthesis of 131I, 125I, 123I and 82Br labelled 5-halo-1-(2-deoxy-2-fluoro-β-d-arabinofuranosyl)uracilsSynthesis of 131I, 125I and 82Br labelled (E)-5-(2-Halovinyl)-2′-deoxyuridinesClinical spectrum of herpes simplex virus infections 1 May 1980Volume 92, Issue 5Page: 696-698KeywordsComaDeath ratesEncephalitisHerpes simplexMorbidityMortality ePublished: 1 December 2008 Issue Published: 1 May 1980 PDF downloadLoading ...