Apheresis and Rheumatoid Arthritis
Authors: JOHN L. DECKER
Journal: Annals of Internal Medicine (1983)

Editorials1 May 1983Apheresis and Rheumatoid ArthritisJOHN L. DECKER, M.D.JOHN L. DECKER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-98-5-666 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptMany remedies are capable of interrupting the pain and inflammation of rheumatoid arthritis, but none are uniformly successful. The adrenal corticosteroid hormones remain the most effective remedy but cause totally unacceptable side effects. Arthrodesis also eliminates pain and swelling but at the expense of joint function. The fast-acting anti-inflammatory agents, rapidly increasing in number, are often successively used, in a search for the most effective yet least harmful agent. The slow-acting drugs (also called, with differing degrees of precision, disease modifying, remission inducing, or second line) are given in addition to find the one that will work without causing unwanted...References1. MCCARTY D and CARRERA G. Intractable rheumatoid arthritis; treatment with combined cyclophosphamide, azathioprine, and hydroxychloraquine. JAMA. 1982;248:1718-23. CrossrefMedlineGoogle Scholar2. WEGELIUS O, LAINE V, LINDSTROM B, and KLOCKARS M. Fistula of the thoracic duct as immunosuppressive treatment in rheumatoid arthritis. Acta Med Scand. 1970;187:539-44. CrossrefMedlineGoogle Scholar3. PAULUS H, MACHLEDER H, LEVINE S, YU D, and MACDONALD N. Lymphocyte involvement in rheumatoid arthritis: studies during thoracic duct drainage. Arthritis Rheum. 1977;20:1249-62. CrossrefMedlineGoogle Scholar4. WALLACE D, GOLDFINGER D, and GATTI R. Plasmapheresis and lymphoplasmapheresis in the management of rheumatoid arthritis. Arthritis Rheum. 1979;22:703-9. CrossrefMedlineGoogle Scholar5. KARSH J, WRIGHT D, KLIPPEL J, DECKER J, DEISSEROTH A, and FLYE M. Lymphocyte depletion by continuous flow cell centrifugation in rheumatoid arthritis: clinical effects. Arthritis Rheum. 1979;22:1055-9. CrossrefMedlineGoogle Scholar6. KOTZIN B, STROBER S, and ENGLEMAN E. Treatment of intractable rheumatoid arthritis with total lymphoid irradiation. N Engl J Med. 1981;305:969-76. CrossrefMedlineGoogle Scholar7. TRENTHAM D, BELLI J, and ANDERSON R. Clinical and immunologic effects of fractionated total lymphoid irradiation in refractory rheumatoid arthritis. N Engl J Med. 1981;305:976-81. CrossrefMedlineGoogle Scholar8. SCHWEITZER S and FOXMAN B. The Effect of Third Party Reimbursement on Expenditures of Medical Care. Washington, D.C.: Department of Health and Human Services, 1981. (National Center for Health Care Technology monograph series). Google Scholar9. ROTHWELL R, DAVIS P, and GORDON P. A controlled study of plasma exchange in the treatment of severe rheumatoid arthritis. Arthritis Rheum. 1980;23:785-90. CrossrefMedlineGoogle Scholar10. WALLACE D, GOLDFINGER D, and LOWE C. A double blind, controlled study of lymphoplasmapheresis versus sham apheresis in rheumatoid arthritis. N Engl J Med. 1982;306:1406-10. CrossrefMedlineGoogle Scholar11. SCOTT D, BACON P, BOTHAMLEY J, ALLEN C, ELSON C, and WALLINGTON T. Plasma exchange in rheumatoid vasculitis. J Rheumatol. 1981;8:433-9. MedlineGoogle Scholar12. KARSH J, KLIPPEL J, PLOTZ P, DECKER J, WRIGHT D, and FLYE M. Lymphapheresis in rheumatoid arthritis: a randomized trial. Arthritis Rheum. 1981;24:867-73. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: JOHN L. DECKER, M.D. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAdvances in therapy of autoimmune diseasesPlasmapheresis for Rheumatoid Arthritis 1 May 1983Volume 98, Issue 5_Part_1 Page: 666-667 Keywords Apheresis Arthralgia Drugs Hormones Inflammation Pain Rheumatic pain Rheumatoid arthritis ePublished: 1 December 2008 Issue Published: 1 May 1983 PDF downloadLoading ...