Vancomycin and Interstitial Nephritis
Authors: EDWARD S. EISENBERG
Journal: Annals of Internal Medicine (1981)

Letters and Corrections1 November 1981Vancomycin and Interstitial NephritisEDWARD S. EISENBERG, M.D., NOAH ROBBINS, M.D., MARGARET LENCI, M.D.EDWARD S. EISENBERG, M.D., NOAH ROBBINS, M.D., MARGARET LENCI, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-95-5-658_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: In the article on acute interstitial nephritis due to drugs (1), Linton and colleagues emphasized the presumed immunologic nature of the disease and the growing list of causative agents. Vancomycin—although documented to produce a wide variety of adverse reactions such as fever, chills, phlebitis, ototoxicity, hypotension, arthralgias, skin rashes, and anaphylaxis—has not been associated with interstitial nephritis (1, 2). Impurities present in the early preparations of the antibiotic may have been responsible for the nephrotoxicity initially reported but not subsequently observed (3). We report the first case of vancomycin-induced interstitial nephritis. A 28-year-old intravenous drug abuser was...References1. LINTON A, CLARK W, DRIEDGER A, TURNBULL D, and LINDSAY R. Acute interstitial nephritis due to drugs: review of the literature with a report of nine cases. Ann Intern Med. 1981;93:735-41. LinkGoogle Scholar2. COOK F and FARRAR W. Vancomycin revisited. Ann Intern Med. 1978;88:813-8. LinkGoogle Scholar3. APPEL G and NEU H. The nephrotoxicity of antimicrobial agents. N Engl J Med. 1977;296:722-8. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: EDWARD S. EISENBERG, M.D.; NOAH ROBBINS, M.D.; MARGARET LENCI, M.D.Affiliations: Montefiore Hospital and Medical Center Albert Einstein College of Medicine Bronx, NY 10467 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byCase Report: Vancomycin-Associated Tubulointerstitial Nephritis in Clinical Practice-Case Report and Review of LiteratureKidney biopsy findings in vancomycin-induced acute kidney injury: a pooled analysisGlycopeptide Hypersensitivity and Adverse ReactionsVancomycin-associated drug-induced hypersensitivity syndromeRare and Overlooked Causes of Acute Kidney InjuryVancomycin and the Risk of AKI: A Systematic Review and Meta-AnalysisMercaptoacetyltriglycine renal scan for the differential diagnosis of acute tubular necrosis and interstitial nephritis associated to vancomycinMercaptoacetyltriglycine renal scan for the differential diagnosis of acute tubular necrosis and interstitial nephritis associated to vancomycinVancomycin-Induced Acute Granulomatous Interstitial Nephritis: Therapeutic OptionsAcute Interstitial Nephritis Associated with Coadministration of Vancomycin and Ceftriaxone: Case Series and Review of the LiteratureFour cases of nafcillin-associated acute interstitial nephritis in one institutionBiopsy-Proved Acute Tubulointerstitial Nephritis and Toxic Epidermal Necrolysis Associated with VancomycinVancomycin-Induced Acute Interstitial NephritisDrug-Induced Acute Renal FailureReview: Acute tubulointerstitial nephritisInterstitial NephritisTubulointerstitial Nephritis Due to VancomycinVancomycin Ototoxicity and NephrotoxicityVancomycin-induced interstitial nephritisHYPERSENSITIVITY ANGIITIS WITH GRANULOMATOUS GLOMERULITIS IN A PATIENT WITH PREEXISTING IgA NEPHROPATHYImmunologically Mediated Nephritis Induced by Toxins and DrugsVancomycin and the KidneyDrug Information Analysis ServiceMiscellaneous antibiotics 1 November 1981Volume 95, Issue 5 Page: 658-658 Keywords Addicts Adverse reactions Antibiotics Arthralgia Drugs Fevers Hypotension Nephritis Rashes Vancomycin ePublished: 1 December 2008 Issue Published: 1 November 1981 PDF downloadLoading ...