tbuckley/cabot-search huggingface dataset:
Correction: Resorcinol and Hypothyroidism
Authors: EDWARD B. RUBY
Journal: Annals of Internal Medicine (1977)

Letters and Corrections1 November 1977Correction: Resorcinol and HypothyroidismEDWARD B. RUBY, M.D.EDWARD B. RUBY, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-87-5-637_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: The article by Dr. Katin and colleagues, "Resorcinol-Induced Hypothyroidism in a Patient on Chronic Hemodialysis" (Ann Intern Med86:447-449, 1977), was certainly of great interest. However, they stated that "the T3R stabilized at a lower than normal level, probably a reflection of decreased binding proteins (albumin, 3.5 g/dl and total proteins, 5.7 g/dl)." Since, according to their article, T3R was meant to represent T3resin uptake, the quoted sentence is obviously in error. As is widely known, the technique of the T3resin uptake is such that with a decrease in thyroid hormone-binding proteins there is an...Reference1. INGBARWOEBER SK: The thyroid gland, in Textbook of Endocrinology, 5th ed., edited by WILLIAMS RH. Philadelphia, W.B. Saunders Company, 1974, pp. 137-140 Google Scholar1. LIMFANGREFETOFFKATZ VVSA: T3 hypothyroidism in uremia: impaired T4 to T3 conversion. International Congress of Nephrology, Florence, Italy, Abstract No. 636, 1975 Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 November 1977Volume 87, Issue 5Page: 637-638KeywordsAlbuminsHypothyroidismProteinsThyroid hormonesTriiodothyronine Issue Published: 1 November 1977 PDF downloadLoading ...
BMJ creates an editorial board
Authors: R. Smith
Journal: BMJ (1997)

The BMJ has been unusual, possibly unique, in not having an editorial board. Over a year ago we began a debate on whether we should create a board, and we decided that we should. Now we have one, and its members are described below and listed at the front of the redesigned journal. There are 35 members from 18 countries, and the members come from all parts of clinical medicine as well as from basic science, statistics, nursing, ethics, health policy, and economics. And, very importantly, we have a patient representative.

The main purpose for developing a board is to help us to prepare the journal for the next century. The members will ensure a steady flow of new ideas from a wide range of specialties, countries, and disciplines. For many years the BMJ has had editorial advisers, who come into our offices every week and help us to decide which papers to publish and how to get them into the best possible form. The advisers are mostly practising doctors or statisticians but also include a health policy expert and a sociologist. We also have a team of medical students, who help us with the Student BMJ . Because they come regularly to our offices we have selected advisers mostly from Britain. In contrast, about three quarters of the editorial board live outside Britain.

We look to the editorial board as well for frank criticism of the BMJ and advice on how it can develop in both the short and the long term. Our board members are increasing our range of contacts, helping us find new writers and reviewers, writing and reviewing for us themselves, and representing us in their countries and disciplines. If you would like to learn more about the BMJ you might care to contact members of …
Day Versus Inpatient Hospitalization: A Controlled Study
Authors: MARVIN I. HERZ, JEAN ENDICOTT, ROBERT L. SPITZER, ALVIN MESNIKOFF
Journal: American Journal of Psychiatry (1971)

The authors report the results of their controlled study to compare the efficacy of day versus inpatient hospitalization for those patients for whom both treatments are equally feasible clinically. Newly admitted inpatients from the catchment area were randomly assigned to either day or inpatient care. Outcome evaluations, including measures of psychopathology and role function, were conducted at various follow-up intervals. The authors found clear evidence of the superiority of day treatment on virtually eveny measure used to evaluate outcome.
HHV8‐related non‐Hodgkin's lymphoma of the spermatic cord in a patient with HIV‐associated multicentric Castleman disease
Authors: Emmanuelle Boulanger, Josette Briere, Philippe Gaulard, Dominique Droz, Eric Oksenhendler
Journal: American Journal of Hematology (2002)

To the Editor: In a recent report, we described the features of 14 cases of Kaposi sarcoma-associated herpesvirus (HHV8/KSHV)-related non-Hodgkin's lymphoma (NHL) occurring during the follow-up of 60 HIVinfected patients with multicentric Castleman disease (MCD) [1].Herein we report a new case of NHL arising in the spermatic cord of a patient from the same cohort study.
A misreading of the evidence?
Authors: S. P Ward
Journal: BMJ (2009)

In their reply to rapid responses about the guideline from the National Institute for Health and Clinical Excellence (NICE) on persistent non-specific low back pain,1 Underwood and Littlejohns say that two systematic reviews report that spinal fusion is effective and informed the NICE low back pain guideline development group2; the group proposes referral for consideration of spinal fusion as an appropriate step in managing low …
A Prospective Evaluation of the Diagnostic Work-Up before Laparoscopic Cholecystectomy
Authors: W. Kruis, H. Roehrig, M. Hardt, C. Pohl, D. Schlosser
Journal: Endoscopy (1997)

A prerequisite for successful laparoscopic cholecystectomy is the exclusion of potential risks such as cholangiolithiasis or anatomical malformations. As there is no general agreement regarding the appropriate preoperative diagnostic work-up, a comparative study of different diagnostic methods was carried out.In 180 consecutive patients admitted to a community hospital for cholecystectomy due to symptomatic cholecystolithiasis, a prospective comparison was carried out of the diagnostic accuracy of patient history, physical examination, laboratory tests, upper gastrointestinal endoscopy, intravenous cholangiography, ultrasonography, and endoscopic retrograde cholangiopancreatography (ERCP).Measurement of the diameter of the common bile duct was found to be a reliable method as a single noninvasive parameter for diagnosing cholangiolithiasis (sensitivity 100%, specificity 93%), with good predictive power (positive predictive value 0.7, negative predictive value 1.0). The best accuracy achieved noninvasively and without sonography was with a combination of positive patient history and gamma-glutamyl transferase findings (sensitivity 58%, specificity 84%, positive predictive value 0.37, negative predictive value 0.93). ERCP detected additional cholangiolithiasis in 19 of 139 patients (13.7%) and anatomical malformations in three patients. In all 19 patients, the bile ducts were cleared of stones endoscopically within 24 hours, prior to laparoscopic cholecystectomy. Among the 163 patients primarily assigned to laparoscopic cholecystectomy, the protocol diagnostic work-up, including ERCP, allocated three patients (1.8%) to open surgery. Conversion from laparoscopic cholecystectomy to open cholecystectomy occurred in a further two of 158 patients (1.3%).These results show that routine ultrasonography prior to laparoscopic cholecystectomy can be recommended in order to determine the diameter of the common bile duct. In patients with a ductal diameter of more than 6 mm, ERCP should be performed. Laparoscopic cholecystectomy can be carried out within 24 hours after ERCP and papillotomy.
Shigella Flexneri Enzootic in Captive Rhesus Monkeys
Authors: G. A. C. Summers, A. H. Linton
Journal: BMJ (1954)

As a contributory cause, however, it is considered that malnutrition may play a part.In Cases 29, 36, 42, and 48 unilateral optic atrophy followed a severe blow in the region of the eye concerned.In no instance was the blow sufficient to have left any radiological evidence of bony damage, nor was any ocular damage seen apart from the optic atrophy.It seems possible that where a severe con- cussion injury has caused damage to the optic nerve the nutritional level may be too low to repair the damage and atrophy may result.One 'of our cases (No. 46)-that of a soldier aged 37 who complained of the fairly sudden onset of blurring and dimness of vision soon after arrival in Egypt-showed points of similarity to a series of cases from the Middle East (Spillane and Scott, 1945).The majority of these cases retained good physical health, and the skin, heart, lungs, and gastro-intestinal tract were not affected.Within a year of this soldier's return to Rhodesia his vision was reduced to R. 6/36, L. 6/24.His disks showed evidence of post- neuritic atrophy, no central scotoma was demonstrated, his fields being appa.ntlyfull, but the use of a Bjerrum screen at 2 metres was not made.There was no significant increase in the number of cases admitted towards the end of the dry season and the begin- ning of the rains, when food supplies became exhausted.It is at this time of the year that we see, for example, many cases of pellagra, night blindness, and scurvy.4. Exogenous Toxins Methyl alcohol, arsenic, and quinine are probably the main toxic agents with which the indigenous population may come into contact.As has already been mentioned, arsenic may play an important part after inadequate treat- ment of syphilis.Quinine and methyl alcohol blindness were not encountered in this series.It is possible that a native medicine-not divulged by the patient-may play a larger part than is suspected at the moment.We failed to discover any definite addicts such as the case of optic neuritis in a Qat addict in Somaliland described by Baird (1952).
Remarks on Hour - Glass Stomach
Authors: B. G. A. Moynihan
Journal: BMJ (1904)

{BY hour-glass stomach (" hour-glass contraction of the stomach," "bilocular stomach," ' Sanduhrmagen," "1'esto-.macbiloculaire ") is understood that condition in which the stomach is divided into two portions by a constriction at any point between the cardiac and pyloric orifices.In one rare, in fact unique, case under my care the stomach was trilocular as the result of a narrowing, due to old ulceration and cicatricial healing, at two separate points, distant about 3 in.from one another.In another, also unique, there were three points of narrowing, one in the body of the stomach, one at or near the pylorus, and one about I in.beyond the ,pylorus, in the duodenum.In this case they were four sacs.As a rule the cardiac complement is larger and has thicker walls than the pyloric.It dilates and becomes hypertrophied 4by reason of the great obstruction met with -t the scarred sand narrow isthiaus, which connects it with the distal por- Cion of the stomach.The forms of hour-glass stomach are many.As a rule the -constriction is near the middle of the organ, or near the pyloric end.The isthmus may be very much indurated, or 't may be tubular with very little or no induration, but with come thickening.In most instances the greater curvature seems to be pulled upwards to the lesser, but in one case I hiave seen the lesser tucked down to the greater. ETIOLOGY.Hour-glass stomach is usually described as being "con- genital" and "acquired."Of these forms the congenital is ,said to be more frequent.Thus Fenwick, in his work, writes: *' In about 45 per cent. of the cases which have been recorded .neitherulcer nor scar could be detected in the stomach, while An the great majority of cases where an ulcer was present it was obviously of more recent formation than the stricture."And again, " That the deformity is a rare result of ulceration is proved by the fact that only one case of the kind is men- 'tioned in the records of the London hospital for forty years, whereas several instances of the congenital form of the dis- oase were encountered during the same period of time."Meckel considered that a congenital hour-glass stomach {might result from an imperfection of development, and
Use of complementary medicines for osteoarthritis--a prospective study
Authors: J Zochling
Journal: Annals of the Rheumatic Diseases (2004)

Patients with osteoarthritis commonly use complementary and alternative medicines (CAM), either as an adjunct to or in place of conventional analgesics.To undertake a prospective investigation of the prevalence of CAM use for osteoarthritis and the direct costs incurred.The subjects were 341 patients with osteoarthritis of the knee or hip drawn from central and northern Sydney, Australia, and comprising 83 community based patients and 258 awaiting joint replacement. Information on CAM use was obtained from prospective three monthly diaries. Variables of interest included health related quality of life scores. Prospective out of pocket costs were recorded over a 12 month follow up period.The prevalence of CAM use was 40%, which falls within the range of previous studies. Average annual expenditure on CAM was 32.25 Australian dollars (range 0 to 603.30). CAM users were more likely to be female (odds ratio (OR) 1.8 (95% confidence interval, 1.1 to 3.0)), reported a higher level of bodily pain (OR 0.97 (0.95 to 0.99)), and were less likely to purchase conventional analgesics (OR 3.3 (1.6 to 7.0)), either prescribed or over the counter. Vitamin supplementation was the most common CAM reported, followed by celery extract, fish oils, and garlic extracts.There are no good quality clinical trials to support the use of most preparations purchased by patients with osteoarthritis. There is a need for patient education on the risks and benefits of complementary medicine in osteoarthritis.
Protein creatinine index and Albustix in assessment of proteinuria.
Authors: A B Shaw, P Risdon, J D Lewis-Jackson
Journal: BMJ (1983)

The protein creatinine index in early morning and random urine specimens was compared with the 24 hour urinary excretion of protein in normal subjects and outpatients with abnormal proteinuria. A protein creatinine index (defined as (mg protein/1 divided by creatinine mmol/1) times 10) below 125 in a random specimen excluded abnormal proteinuria, whereas an index of more than 136 indicated the presence of pathological proteinuria. The index for random specimens provided a useful semiquantitative assessment of the 24 hour excretion of protein (mg protein/24 hours), but the index for early morning specimens was less reliable. Errors with Albustix were partly due to intra and inter observer variations in the interpretation of the colour formed when compared with the chart provided. It is proposed that the protein creatinine index on random urine samples should be used to supplement dipsticks in screening for proteinuria in cases where misclassification would be serious.
What domain integration could not be
Authors: Philip Robbins
Journal: Behavioral and Brain Sciences (2002)

Carruthers argues that natural language is the medium of non-domain-specific thought in humans. The general idea is that a certain type of thinking is conducted in natural language. It’ not exactly clear, however, what type of thinking this is. I suggest two different ways of interpreting Carruthers’ thesis on this point and argue that neither of them squares well with central-process modularism.
Clonal expansion of immunoglobulin M+CD27+ B cells in HCV-associated mixed cryoglobulinemia
Authors: Edgar D. Charles, Rashidah M. Green, Svetlana Marukian, Andrew H. Talal, Gerond V. Lake-Bakaar, Ira M. Jacobson, Charles M. Rice, Lynn B. Dustin
Journal: Blood (2007)
Bronchoalveolar lavage cytology resembles sarcoidosis in a subgroup of granulomatous CVID
Authors: Jean-Marc Naccache, Diane Bouvry, Dominique Valeyre
Journal: European Respiratory Journal (2014)

signs and bronchiectasis predominated in CVID.In line with their findings, in our cohort with proven granulomatous disease, the majority of HRCTs demonstrated macronodular lung involvement (eight out of 11 patients).The two patients with micronodular involvement showed a randomly distributed pattern, which also differs to the characteristic perilymphatic distribution in sarcoidosis, as already shown by BOUVRY et al. [1].Moreover, some patients presented with predominant coarse reticular lines or groundglass lesions.It is intriguing to speculate whether the difference in CD4/CD8 ratio reflects different forms or stages of pulmonary inflammation in CVID, which may correlate to certain computed tomography morphology.This has been previously described in sarcoidosis, where lower CD4/CD8 ratios and increased neutrophils correlated with progressive, fibrotic disease and the need for steroid treatment [3][4][5].In our small CVID cohort, lung function and computed tomography findings were mostly stable during follow-up, suggesting that a high CD4/CD8 ratio in granulomatous CVID is associated with a mild and nonprogressive ILD (table 1).Only two patients showed a deterioration of lung function parameters.Interestingly, both of these patients showed rather low CD4/CD8 ratios in comparison to the total study population (2.0 and 3.8).In conclusion, in addition to the report by BOUVRY et al.[1], we found that in a subgroup of CVID patients with histologically confirmed granuloma formation, BAL cytology resembles sarcoidosis.All patients presented with high BAL lymphocytosis, high CD4/CD8 ratio and the majority with nodular lung disease on computed tomography.Thus, differences in BAL cytology and computed tomography morphology most likely reflect heterogeneity in CVID-associated granulomatous and interstitial lung disease.Our preliminary data suggest a rather favourable prognosis of ILD in this subgroup of CVID with high CD4/CD8 ratio in the BAL.Some of these findings may potentially guide management and predict outcome of these patients, but larger studies are needed to determine diagnostic and prognostic value of specific markers during detailed characterisation of interstitial lung disease in this heterogeneous disease.
Grace Revere Osler: A Turn of the Century Professor's Wife
Authors: GEORGE T. HARRELL
Journal: Annals of Internal Medicine (1980)

Editorial Notes1 September 1980Grace Revere Osler: A Turn of the Century Professor's WifeGEORGE T. HARRELL, M.D.GEORGE T. HARRELL, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-93-3-504 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptWilliam Osler, the premier medical teacher of his day, was a bachelor when he came to The Johns Hopkins Hospital in 1889 on its opening. He saw patients on the wards but spent most of his time writing his textbook while living in the hospital. The book was published in 1892. He married 4 months later and bought his first house. His income from practice rose dramatically the next year, in part, perhaps, because of his rising reputation from his writing but also because of the organization of his life, including practice, by his new wife. The medical school did...References1. HARRELL G. Osler's practice. Bull Hist Med. 1973;47:545-68. MedlineGoogle Scholar2. OSLER W. [Letter]. Located at Osler Library, McGill University, Montreal. Cushing papers, ace. 417/93, folder 1897. [Feb 8, 1921], letter. Google Scholar3. HARRELL G. Lady Osler. Bull Hist Med. 1979;53:81-99. MedlineGoogle Scholar4. OSLER W. [Letter to Harold Parsons]. Located at Osler Library, McGill University, Montreal. Cushing papers, ace. 417, folder 116 (Jan-June 1915) copy of Jan 27, 1915, letter. Google Scholar5. HARRELL G. The Osler's Son—Revere: their greatest joy and sorrow. Bull Hist Med. 1980; in press. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: 2010 Eastridge Road; Timonium, Maryland PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe University of Pennsylvania Medical School Commencement of 1889A Gift from Oxford: The Osler-Thomas Connection 1 September 1980Volume 93, Issue 3Page: 504-505 Issue Published: 1 September 1980 PDF downloadLoading ...
Ventricular Fibrillation Associated with an Electrically Operated Bed
Authors: Saul Aronow, John M. R. Bruner, Edward F. Siegal, L. J. Sloss
Journal: New England Journal of Medicine (1969)

A PATIENT was thrown into ventricular fibrillation when the controller of his electrically operated bed was submerged in urine. Current from a conventional 120-volt grounded power line passed from the controller, into the urine pool and through the patient's buttocks and returned to ground via a monitor electrode pasted to the precordial skin. Case Report A 53-year-old man was admitted to an intensive-care unit of the Massachusetts General Hospital on May 30, 1968, with an extensive acute anterolateral myocardial infarction. His condition stabilized rapidly, and there was no indication of congestive heart failure. Continuous electrocardiographic monitoring disclosed no arrhythmias. At . . .
Points from Letters: Breast-milk Jaundice and Oral Contraceptives
Authors: B. S. B. Wood, Y. K. Wong
Journal: BMJ (1971)

gases, lactate metabolism, and acid-base balance during and after exercise, and some of the results are to be published shortly.Basically we found that none of these factors could explain the origin of exercise-induced asthma or the difference with different forms of exercise.Likewise, we have studied lung volumes and mechanical properties and found that they reflect rather than cause the asthma.Finally, we would like to repeat our earlier suggestion that the mechanism of exercise-induced asthma and the difference between the severe constriction due to running compared with the virtual absence during swimming may reflect neuro- muscular differences in the types of exercise.
RAPID LITHOTRITYOR LITHOLAPAXY, ITS LATER IMPROVEMENTS AND ITS PRESENT CONDITION.
Authors: EDMUND ANDREWS
Journal: JAMA (1884)

Lithotrity at one sitting, as planned and developed by Prof. Bigelow, has revolutionized the treatment of vesical calculus. Those most familiar with this method will agree with me that it is destined not only to supersede the slow lithotrity, but to abolish lithotomy itself in forty-nine fiftieths of the adult cases. I have now performed this operation eighteen times with only one death, though the patients averaged nearly sixty years of age, and the stones were mostly very large. In one of the successful cases the crushed fragments weighed two ounces and five drams, and the patient was about 70 years of age. No such success could have been obtained by cutting on such unpromising cases. Passing by as irrelevant the unpleasant personal controversy between Prof. Bigelow and Sir Henry Thompson, a few words are proper respecting the newly coined word, litholapaxy. By the laws of literature, Prof. Bigelow is
PREDICTORS OF OUTCOME IN ASYMPTOMATIC PATIENTS WITH SEVERE RHEUMATIC MITRAL REGURGITATION
Authors: Duk-Hyun Kang, Dae-Hee Kim, Byung Joo Sun, Jin Oh Na, Jong Seon Park, Jong-Min Song, Hyun Song, Joo Hee Zo, Jae-Kwan Song, Jae-Won Lee
Journal: Journal of the American College of Cardiology (2010)
OBSERVATIONS ON LANGERHANS CELLS IN LEPROSY.
Authors: A. S. BREATHNACH, M. S. BIRBECK, J. D. EVERALL
Journal: British Journal of Dermatology (1962)

Journal Article OBSERVATIONS ON LANGERHANS CELLS IN LEPROSY. Get access A. S. BREATHNACH, M.Sc., M.D., A. S. BREATHNACH, M.Sc., M.D. Department of Anatomy, St. Mary's Hospital Medical School, London. W.2 Search for other works by this author on: Oxford Academic Google Scholar M. S. BIRBECK, M.A, M. S. BIRBECK, M.A Chester Beatty Research Institute, Royal Marsden Hospital, London. S.W.3 Search for other works by this author on: Oxford Academic Google Scholar J. D. EVERALL, M.R.C.P. J. D. EVERALL, M.R.C.P. Department of Dermatology, St. Mary's Hospital, London, W.2 Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 74, Issue 7, 1 July 1962, Pages 243–253, https://doi.org/10.1111/j.1365-2133.1962.tb13501.x Published: 01 July 1962