The<i>Klebsiella-Enterobacter-Serratia</i>Division
Authors: THEODORE C. EICKHOFF
Journal: Annals of Internal Medicine (1966)

Article1 December 1966The Klebsiella-Enterobacter-Serratia DivisionBiochemical and Serologic Characteristics and Susceptibility to AntibioticsTHEODORE C. EICKHOFF, M.D., BRUCE W. STEINHAUER, M.D., MAXWELL FINLAND, M.D., F.A.C.P.THEODORE C. EICKHOFF, M.D.Search for more papers by this author, BRUCE W. STEINHAUER, M.D.Search for more papers by this author, MAXWELL FINLAND, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-65-6-1163 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptOrganisms of the tribe Klebsielleae, comprised of the genera Klebsiella, Enterobacter, and Serratia, had been recognized only rarely as primary pathogens in humans before the introduction of modern chemotherapy. Since that time, however, they, along with other gram-negative bacilli, have assumed increasing importance as causes of serious infection in hospitalized patients (1-4). Within the past 8 years the number of patients with bacteremia due to Klebsielleae has almost doubled in the Boston City Hospital (5) while the number of admissions to that hospital has remained virtually unchanged.Epidemiologic studies of theKlebsiella-Enterobacter-Serratiadivision have been hindered in the past because...References1. FINLANDJONESBARNES MWFMW: Changes in the occurrence of serious bacterial infections since the introduction of antibacterial agents. Trans. Ass. Amer. Physicians 72: 305, 1959. Google Scholar2. FINLAND M: Treatment of pneumonia and other serious infections. New Eng. J. Med. 263: 207, 1960. CrossrefMedlineGoogle Scholar3. YOW EM: Clinical significance of rising incidence of infections due to gram-negative bacilli. Postgrad. Med. 17: 413, 1955. CrossrefMedlineGoogle Scholar4. 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Intern. Med. (Chicago) 114: 329, 1964. CrossrefMedlineGoogle Scholar35. TURCKANDERSONSMITHWALLACEPETERSDORF MKNRHJFRG: Laboratory and clinical evaluation of a new antibiotic—cephalothin. Ann. Intern. Med. 63: 199, 1965. LinkGoogle Scholar36. FLEMINGGOLDNERGLASS PCMDG: Observations on the nature, distribution, and significance of cephalosporinase. Lancet 1: 1399, 1963. CrossrefMedlineGoogle Scholar37. BENNERMICKELWAITBRODIEKIRBY EJJSJLWM: Natural and acquired resistance of Klebsiella-Aerobacter to cephalothin and cephaloridine. Proc. Soc. Exp. Biol. Med. 119: 536, 1965. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: THEODORE C. EICKHOFF, M.D.; BRUCE W. STEINHAUER, M.D.; MAXWELL FINLAND, M.D., F.A.C.P.Affiliations: Boston, Massachusetts, and Atlanta, GeorgiaFrom the Thorndike Memorial Laboratory, Second and Fourth (Harvard) Medical Services, Boston City Hospital; the Department of Medicine, Harvard Medical School, Boston, Mass.; and the Epidemiology Branch, Communicable Disease Center, U. S. Public Health Service, Atlanta, Ga.Supported in part by grants AI00023 and TIAI00068, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.At the time of this study Drs. Eickhoff and Steinhauer were Research Fellows in Medicine at Thorndike Memorial Laboratory and Harvard Medical School.Requests for reprints should be addressed to M. Finland, M.D., Thorndike Memorial Laboratory, Boston City Hospital, Boston, Mass. 02118. 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STEINHAUER, M.D., THEODORE C. EICKHOFF, M.D., JAY WARD KISLAK, M.D., MAXWELL FINLAND, M.D., F.A.C.P. 1 December 1966Volume 65, Issue 6Page: 1163-1179KeywordsEnterobacterHospital medicineInfectious disease epidemiologyInfectious diseasesKlebsiellaKlebsiella pneumoniaeMedical servicesPathogensPneumoniaResearch laboratories ePublished: 1 December 2008 Issue Published: 1 December 1966 Copyright & PermissionsCopyright ©, 1966, by The American College of PhysiciansPDF downloadLoading ...