Bilateral Parotid Enlargement and Starch Ingestion
Authors: MARK SILVERMAN
Journal: Annals of Internal Medicine (1966)

Case Studies1 April 1966Bilateral Parotid Enlargement and Starch IngestionMARK SILVERMAN, M.D., ROBERT L. PERKINS, M.D.MARK SILVERMAN, M.D.Search for more papers by this author, ROBERT L. PERKINS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-64-4-842 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe finding of bilateral, asymptomatic parotid gland enlargement associated with prolonged starch ingestion has been reported once in the literature. In that case, Merkatz (1) described a 36-year-old Negro female chronic starch eater whose dietary history showed minimal protein intake. The suggested primary relationship between starch ingestion and parotid enlargement might be subject to criticism since parotid swelling has been attributed alone to various states of malnutrition. Recently a patient with chronic starch ingestion and bilateral parotid enlargement came to our attention. This patient had adequate nutritional intake. This case is reported to strengthen the proposed etiologic relationship between starch...References1. MERKATZ IR: Parotid enlargement resulting from excessive ingestion of starch. New Eng. J. Med. 265: 1304, 1961. CrossrefMedlineGoogle Scholar2. DUPLESSIS DJ: Parotid enlargement in malnutrition. S. Afr. Med. J. 30: 700, 1956. MedlineGoogle Scholar3. GILLMANGILBERTGILLMAN JCT: The Bantu salivary glands in chronic malnutrition with a brief consideration of the parenchyma-interstitial tissue relationship. S. Afr. J. Med. Sci. 12: 99, 1947. MedlineGoogle Scholar4. ROTHBELLDUGGAN ENJJ: Enlargement of the parotid gland in disease of the liver. Amer. J. Med. 22: 367, 1957. CrossrefMedlineGoogle Scholar5. DAVIES JN: The essential pathology of kwashiorkor. Lancet 1: 317, 1948. CrossrefMedlineGoogle Scholar6. NASHMORRISON LL: Asymptomatic chronic enlargement of the parotid glands. Ann. Otol. 58: 646, 1949. Google Scholar7. MILLER RS: The problem of pellagra. Amer. Med. 31: 211, 1925. Google Scholar8. KATSILAMBROS L: Asymptomatic enlargement of the parotid glands. JAMA 178: 513, 1961. CrossrefMedlineGoogle Scholar9. BECK A: Inflammation of the salivary glands. Surg. Gynec. Obstet. 74: 604, 1942. Google Scholar10. CURTISSWENSON GRE: Thiouracil and its allies in the treatment of hyperthyroidism. Int. Abstr. Surg. 86: 105, 1948. Google Scholar11. RAMAGEBINNIEMCCALL JSGGAJ: Bilateral adenolymphoma of the parotid glands. Brit. J. Surg. 31: 189, 1943. CrossrefGoogle Scholar12. WALDENSTROM J: Some observations on uveoparotitis and allied conditions with special reference to the symptoms from the nervous system. Acta Med. Scand. 91: 53, 1937. CrossrefGoogle Scholar13. PEARSON B: Recurrent swellings of the parotid gland. Gut 2: 210, 1961. CrossrefMedlineGoogle Scholar14. LUTMANFAVATA FCBV: Keratoconjunctivitis sicca and buccoglossopharyngitis sicca with enlargement of parotid glands. Arch. Ophthal. (Chicago) 35: 227, 1946. CrossrefMedlineGoogle Scholar15. REIMANNLINDQUIST HJ: Periodic sialorrhea, report of a case. JAMA 149: 1465, 1952. CrossrefMedlineGoogle Scholar16. PHILLIPS LG: Parotid swelling associated with lactation: with the report of a case. Amer. J. Obstet. Gynec. 22: 434, 1931. CrossrefGoogle Scholar17. JOHN JH: Mikulicz's disease and diabetes. JAMA 101: 184, 1933. CrossrefGoogle Scholar18. BASSMENDLOWITZ HEM: The relationship of chronic recurrent sialoadenitis to the alarm reaction. Ann. Otol. 58: 868, 1949. Google Scholar19. BORSANYIBLANCHARD SC: Asymptomatic parotid swelling and isoproterenol. Laryngoscope 72: 1777, 1962. MedlineGoogle Scholar20. PEARSON B: Two cases of recurrent swelling of the parotids. Guy Hosp. Rep. 86: 333, 1936. Google Scholar21. BURTON-FANNING FW: Periodic swelling of the salivary glands. Brit. Med. J. 2: 517, 1925. Google Scholar22. SMITH M: Familial incidence of sialectasis. Brit. Med. J. 2: 1359, 1953. CrossrefMedlineGoogle Scholar23. MOSBECKOSTERGAARD KRISTENSEN JHP: Chronic sialoadenitis caused by autoimmunization. Acta Med. Scand. 168: 147, 1960. CrossrefMedlineGoogle Scholar24. SCHAFFERJACOBSEN AJAW: Mikulicz's syndrome. Amer. J. Dis. Child. 34: 327, 1927. CrossrefGoogle Scholar25. DUGGANROTHBELL JJEN: Asymptomatic enlargement of the parotid glands. New Eng. J. Med. 257: 1262, 1957. CrossrefMedlineGoogle Scholar26. EHRLICH M: Contribution à la pathologie des parotides. Presse Med. 30: 138, 1922. Google Scholar27. EIGLERBOENNINGHAUS GHG: Parotisschwellungen bei dystrophikern. Arztl. Wschr. 3: 45, 1948. MedlineGoogle Scholar28. The parotid glands and nutritional diseases. Nutr. Rev. 15: 264, 1957. MedlineGoogle Scholar29. LUCKNERSCRIBA HK: Speicheldrusenvergrosserungen beim experimentellen ernahrungsodem. Arztl. Wchnschr. 3: 519, 1948. MedlineGoogle Scholar30. MCCANCEDEANBARRETT RARFAM: Enlargement of the parotid glands, in Studies of Undernutrition, Wuppertal 1964-9. Medical Research Council Special Report Series No. 275, London, 1951. Google Scholar31. BONNINMORETTIGEYER HGA: Les grosses parotides des cirrhoses alcoholiques. Presse Med. 62: 1449, 1954. MedlineGoogle Scholar32. BESTTAYLOR CHNB: Salivary glands and secretion of saliva, in Physiological Basis of Medical Practice, 7th ed. The Williams & Wilkins Co., Baltimore, 1961, p. 585. Google Scholar33. HEMENWAYALLEN GWGW: Chronic enlargement of the parotid gland, hypertrophy and fatty infiltration. Laryngoscope 69: 1508, 1959. CrossrefMedlineGoogle Scholar34. SANSTEADKOEHNSESSIONS HCS: Enlargement of the parotid gland in malnutrition. Amer. J. Clin. Nutr. 3: 198, 1955. CrossrefMedlineGoogle Scholar35. MENGEL CE: Personal communication. Google Scholar36. FERGUSONKEATON JHAG: Studies of the diets of pregnant women in Mississippi. I. Ingestion of clay and laundry starch. New Orleans Med. Surg. J. 102: 460, 1950. Google Scholar37. DICKENSFORD DRN: Geophagy (dirt eating) among Mississippi Negro school children. Amer. Soc. Rev. 7: 59, 1942. CrossrefGoogle Scholar38. EDWARDSMCSWAINHAIRE CHHS: Odd dietary practices of women. J. Amer. Diet. Ass. 30: 976, 1954. CrossrefMedlineGoogle Scholar39. SILVERMAN ME: Unpublished data. Google Scholar40. HERTZ H: Notes on clay and starch eating among Negroes in a Southern urban community. Social Forces 25: 343, 1947. CrossrefGoogle Scholar41. EDWARDSMCDONALDMITCHELLJONESMASONKEMPLAINGTRIGG CHSJRLLAMDL: Clay-and-cornstarch-eating women. J. Amer. Diet. Ass. 35: 810, 1959. CrossrefMedlineGoogle Scholar42. MENGELCARTERHORTON CEWAES: Geophagia with iron deficiency and hypokalemia: cachexia africana. Arch. Intern. Med. (Chicago) 114: 470, 1964. CrossrefMedlineGoogle Scholar43. CRAGIN FW: Observations on cachexia africana or dirt eating. Amer. J. Med. Sci. 17: 356, 1835. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Columbus, OhioFrom the Department of Medicine, Ohio State University Hospitals, Columbus, Ohio.This study was presented in part at the Annual Awards Meeting of the Columbus, Ohio Society of Internal Medicine, June 15, 1965.Request for reprints should be addressed to Robert L. Perkins, M.D., University Hospital, N-937, 410 West 10th Ave., Columbus, Ohio 43210. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited BySalivary changes and dental erosion in bulimia nervosaIdiopathic salivary gland enlargement (sialadenosis) in dogs: a microscopic studyPainful buccal mass in a patient with bulimia nervosaAnémie par carence en fer et pagophagie. A propos d'un casParotid gland enlargement and female reproductive performance in a Papua New Guinea highland populationAmylophagia and iron deficiency anemiaOral signs and symptoms in the diagnosis of bulimiaA morphometric study of submandibular salivary gland changes in streptozotocin-induced diabetic ratsOral Pathology in Papua New GuineaAsymptomatic parotid gland enlargement in diabetes mellitusBenign Parotid Enlargement in BulimiaPHILIP A. LEVIN, M.D., JAMES M. FALKO, M.D., KATHARINE DIXON, M.D., ELIZABETH M. GALLUP, B.S., WILLIAM SAUNDERS, M.D.Geophagic lead nephropathy: Case reportBenign Parotid Swellings: A ReviewGuide to Better Evaluation of Antepartum NutritionMinor salivary gland involvement in Sjögren's syndromeEnlargement of salivary glandsParotid Enlargement Due to AlcoholismAsymptomatic Parotid Gland Enlargement in Diabetes MellitusDEREK DAVIDSON, M.D., BERNARD S. LEIBEL, M.D., BARNET BERRIS, M.D., F.A.C.P., F.R.C.P.(CAN)Recurrent Parotid Swelling, Arterial Hypertension, and Pancreatitis 1 April 1966Volume 64, Issue 4Page: 842-846KeywordsHospital medicineInflammationIngestionMalnutritionNutritionParotid glandsProteinsStarches Issue Published: 1 April 1966 PDF DownloadLoading ...