Update in Pulmonary Medicine
Authors: Michael S. Niederman
Journal: Annals of Internal Medicine (1998)

Updates1 February 1998Update in Pulmonary MedicineMichael S. Niederman, MD and Stephen P. Peters, MDMichael S. Niederman, MDFrom State University of New York at Stony Brook, Stony Brook, New York, and Jefferson Medical College, Philadelphia, Pennsylvania. and Stephen P. Peters, MDFrom State University of New York at Stony Brook, Stony Brook, New York, and Jefferson Medical College, Philadelphia, Pennsylvania.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-128-3-199802010-00007 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Asthma and pneumonia received much attention in clinical research published in 1996. Asthma studies focused on the optimal use of β-adrenergic agents, inhaled steroids, and leukotriene-inhibiting drugs. Studies of chronic obstructive pulmonary disease focused on the mechanisms of benefit from lung volume reduction surgery. Systematic reviews and large population studies provided more insight into community-acquired pneumonia. Finally, carefully developed guidelines for the management of hospital-acquired pneumonia were published.AsthmaAsthma affects about 5% to 7% of Americans. Research on this common illness is aimed at finding the optimal treatment regimen for mild asthma and for determining the best approach to ...References1. Sears MR, Taylor DR, Print CG, Lake DC, Li QQ, Flannery EM, et al. Regular inhaled β-agonist treatment in bronchial asthma. Lancet. 1990; 336:1391-6. Google Scholar2. Apter AJ, Reisine ST, Willard A, Clive J, Wells M, Metersky M, et al. The effect of inhaled albuterol in moderate to severe asthma. J Allergy Clin Immunol. 1996; 98:295-301. Google Scholar3. Ind PW. Anti-leukotriene intervention: is there adequate information for clinical use in asthma? Respir Med. 1996; 90:575-8. Google Scholar4. Clark DJ, Lipworth BJ. Adrenal suppression with chronic dosing of fluticasone propionate compared with budesonide in adult asthmatic patients. Thorax. 1997; 52:55-8. Google Scholar5. Buckley LM, Leib ES, Cartularo KS, Vacek PM, Cooper SM. Calcium and vitamin D3 supplementation prevents bone loss in the spine secondary to low-dose corticosteroids in patients with rheumatoid arthritis. A randomized, double-blind, placebo-controlled trial. Ann Intern Med. 1996; 125:961-8. Google Scholar6. Recommendations for the prevention and treatment of glucocorticoid-induced osteoporosis. American College of Rheumatology Task Force on Osteoporosis Guidelines. Arthritis Rheum. 1996; 39:1791-801. Google Scholar7. Adachi JD, Bensen WG, Brown J, Hanley D, Hodsman A, Josse R, et al. Intermittent etidronate therapy to prevent corticosteroid-induced osteoporosis. N Engl J Med. 1997; 337:382-7. Google Scholar8. Fine MJ, Smith MA, Carson CA, Mutha SS, Sankey SS, Weissfeld LA, et al. Prognosis and outcomes of patients with community-acquired pneumonia. A meta-analysis. JAMA. 1996; 275:134-41. Google Scholar9. Bartlett JG. Update in infectious diseases. Ann Intern Med. 1997; 127:217-24. Google Scholar10. Niederman MS, Bass JB Jr, Campbell GD, Fein AM, Grossman RF, Mandell LA, et al. Guidelines for the initial management of adults with community-acquired pneumonia: diagnosis, assessment of severity, and initial antimicrobial therapy. American Thoracic Society. Medical Section of the American Lung Association. Am Rev Respir Dis. 1993; 148:1418-26. Google Scholar11. Kauppinen MT, Saikku P, Kujala P, Herva E, Syrjala H. Clinical picture of community-acquired Chlamydia pneumoniae pneumonia requiring hospital treatment: a comparison between chlamydial and pneumococcal pneumonia. Thorax. 1996; 51:185-9. Google Scholar12. Chan R, Hemeryck L, O'Regan M, Clancy L, Feely J. Oral versus intravenous atibiotics for community acquired lower respiratory tract infection in a general hospital: open, randomised controlled trial. BMJ. 1995; 310:1360-2. Google Scholar13. Coley CM, Li YH, Medsger AR, Marrie TJ, Fine MJ, Kapoor WN, et al. Preferences for home vs hospital care among low-risk patients with community-acquired pneumonia. Arch Intern Med. 1996; 156:1565-71. Google Scholar14. Papazian L, Bregeon F, Thirion X, Gregoire R, Saux P, Denis JP, et al. Effect of ventilator-associated pneumonia on mortality and morbidity. Am J Respir Crit Care Med. 1996; 154:91-7. Google Scholar15. Pestotnik SL, Classen DC, Evans RS, Burke JP. Implementing antibiotic practice guidelines through computer-assisted decision support: clinical and financial outcomes. Ann Intern Med. 1996; 124:884-90. Google Scholar Author, Article, and Disclosure InformationAffiliations: From State University of New York at Stony Brook, Stony Brook, New York, and Jefferson Medical College, Philadelphia, Pennsylvania.Corresponding Author: Michael S. Niederman, MD, Pulmonary and Critical Care Medicine, Winthrop-University Hospital, 222 Station Plaza North, Suite 400, Mineola, NY 11501.Current Author Addresses: Dr. Niederman: Pulmonary and Critical Care Medicine, Winthrop-University Hospital, 222 Station Plaza North, Suite 400, Mineola, NY 11501. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe Role of S1P and the Related Signaling Pathway in the Development of Tissue FibrosisInhibition of bleomycin-induced pulmonary fibrosis by bone marrow-derived mesenchymal stem cells might be mediated by decreasing MMP9, TIMP-1, INF- γ and TGF- βAcute PneumoniaTigecycline in the Treatment of Community-Acquired PneumoniaThe risk factors for mortality of community-acquired pneumonia in JapanAn economic and outcomes assessment of first-line monotherapy in the treatment of community-acquired pneumonia within managed carePenicillin and Macrolide Resistance in Pneumococcal Pneumonia: Does In Vitro Resistance Affect Clinical Outcomes?PREDICTORS OF LENGTH OF HOSPITAL STAY IN COMMUNITY-ACQUIRED PNEUMONIAEfficacy of Amoxicillin-Sulbactam, Given Twice-a-Day, for the Treatment of Community-Acquired Pneumonia: A Clinical Trial Based on a Pharmacodynamic ModelAdherence to ATS Guidelines for Hospitalized Patients with Community-Acquired Pneumonia 1 February 1998Volume 128, Issue 3Page: 208-215KeywordsAntibioticsAsthmaDrugsLeukotrieneLungsMortalityOxygenPathogensPneumoniaSteroids Issue Published: 1 February 1998 Copyright & PermissionsCopyright © 1998 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...