Pregnancy After Renal Transplantation
Authors: George E. Tagatz, Richard L. Simmons
Journal: Annals of Internal Medicine (1975)

Editorial Notes1 January 1975Pregnancy After Renal TransplantationGEORGE E. TAGATZ, M.D., RICHARD L. SIMMONS, M.D.GEORGE E. TAGATZ, M.D.Search for more papers by this author, RICHARD L. SIMMONS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-82-1-113 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptRenal failure induces hypogonadotrophic hypogonadism; when the endogenous creatinine clearance decreases in women to 4 ml/min, menses cease (1). The hypothalamic suppression accompanying uremia exemplifies a functional interdependence that ensures infertility in patients whose survival is threatened. Renal transplantation saves life and restores renal function; return of gonadotrophin secretion follows. The incidental return of fertility potential poses significant problems: patients who desire to become parents have a decreased life expectancy and may be chronically ill; female recipients and their fetuses face complications uniquely associated with pregnancy.One hundred thirty-six pregnancies after renal transplantation are recorded in the admittedly incomplete files of...References1. GOODWIN N, VALENTI C, and HALL J: Effects of uremia and chronic hemodialysis on the reproductive cycle. Am J Obstet Gynecol 100:528-535, 1968 CrossrefMedlineGoogle Scholar2. : Twelfth Report of the Human Renal Transplant Registry. JAMA. In press Google Scholar3. MOORE T and HUME D: The period and nature of hazard in clinical renal transplantation. II. The hazard to transplant kidney function. Ann Surg 170:12-24, 1969 CrossrefMedlineGoogle Scholar4. CAPLAN R, DOSSETOR J, and MAUGHAN G: Pregnancy following cadaver kidney homotransplantation. Am J Obstet Gynecol 106: 644-648, 1970 CrossrefMedlineGoogle Scholar5. BOLOGNESE R, CORSON S, and TOUCHSTONE J: Factors affecting the yield of urinary estriol. Obstet Gynecol 39:683-687, 1972 MedlineGoogle Scholar6. PENN I, MAKOWSKI E, and DROEGEMUELLER W: Parenthood in renal monograft recipients. JAMA 216:1755-1761, 1971 CrossrefMedlineGoogle Scholar7. BONGIOVANNI A and MCPADDEN A: Steroids during pregnancy and possible fetal consequences. Fertil Steril 11:181-186, 1960 CrossrefMedlineGoogle Scholar8. WARREL D and TAYLOR R: Outcome for the foetus of mothers receiving prednisolone during pregnancy. Lancet 1:117-118, 1968 CrossrefMedlineGoogle Scholar9. WILSON M: The effect of maternal medications on the fetus and the newborn infant. Am J Obstet Gynecol 83:818-825, 1962 CrossrefMedlineGoogle Scholar10. LOWER G, STEVENS L, and NAJARIAN J: Problems from immunosuppressives during pregnancy. Am J Obstet Gynecol 111: 1120-1121, 1971 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: GEORGE E. TAGATZ, M.D.; RICHARD L. SIMMONS, M.D. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAzathioprine: its uses in dermatologyThe new FDA labeling rule: impact on prescribing rheumatological medications during pregnancyThe treatment of atopic dermatitis with systemic immunosuppressive agentsInternistische Probleme bei Gravidität nach NierentransplantationSuccessful pregnancy in a liver transplant patientSuccessful pregnancy after renal transplantation in a patient with a urinary diversionRenal Disease in PregnancyPLANNED PREGNANCY IN A RENAL TRANSPLANT RECIPIENTPregnancy following renal transplantation 1 January 1975Volume 82, Issue 1Page: 113-114KeywordsCreatinineFetusesHypogonadismInfertilityLife expectancyPregnancyRenal failureRenal transplantation ePublished: 1 December 2008 Issue Published: 1 January 1975 PDF downloadLoading ...