Nitroblue Tetrazolium Dye Test
Authors: GEORGE MATULA
Journal: Annals of Internal Medicine (1973)

Comments and Corrections1 November 1973Nitroblue Tetrazolium Dye TestGEORGE MATULA, M.D., MITZI RAAS, B.A.GEORGE MATULA, M.D.Search for more papers by this author, MITZI RAAS, B.A.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-79-5-758 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: The report of Lauter and associates (Ann Intern Med 79:59-62, 1973), that the nitroblue tetrazolium dye test was positive in 16 patients with myocardial infarction and 1 with pulmonary emboli, is contrary to our experience. We have found the test to be negative in 45 patients with myocardial infarction and in 24 patients with pulmonary emboli.A probable explanation for this discrepancy is represented in Table 1, which compares results in blood samples collected by two methods. The tests were done by the two methods simultaneously in each subject and the slides were coded for reading. Other...References References1. MANDELLFULLER GL: Nitroblue tetrazolium dye test: a diagnostic aid in tuberculosis. Am Rev Resp Dis 105:123-125, 1972 MedlineGoogle Scholar2. PARKFIKRIGSMITHWICK BSE: Infection and nitro-blue-tetrazolium reduction by neutrophils. A diagnostic aid. Lancet 2:532-534, 1968 CrossrefMedlineGoogle Scholar3. MATULAPATERSON GP: Spontaneous in vitro reduction of nitroblue tetrazolium by neutrophils of adult patients with bacterial infection. N Engl J Med 285:311-317, 1971 CrossrefMedlineGoogle Scholar4. FEIGINSHACKELFORDCHOI RPS: Nitroblue tetrazolium dye test as an aid in the differential diagnosis of febrile disorders. J Pediatr 78:230-237, 1971 CrossrefMedlineGoogle Scholar5. HUMBERTMARKSHATHAWAY JMW: The histochemical nitroblue tetrazolium reduction test in the differential diagnosis of acute infections. Pediatrics 48:259-267, 1971 MedlineGoogle Scholar1. WOLLMANDAVIDBRENNAN MDB: The nitroblue tetrazolium test. Usefulness in detecting bacterial infections in uremic and immunosuppressed renal transplant patients. Lancet 2:289-292, 1972 CrossrefMedlineGoogle Scholar2. NORDENREESE CR: Oral contraceptives and NBT test (letter). N Engl J Med 287:254, 1972 CrossrefMedlineGoogle Scholar3. MANDELLFULLER GL: Nitroblue tetrazolium dye test: a diagnostic aid in tuberculosis. Am Rev Resp Dis 105:123-125, 1972 MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: The Permanente Medical Group San Francisco, California PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByFused Triazolo Isoquinoline Derivatives—Design, Synthesis, and Biological EvaluationDesign and synthesis of [1,2,4]-triazolo isoquinoline derivatives via 1, 3-dipolar [3 + 2] cycloaddition: Reaction of azomethine imine with ethyl cyanoformate as unknown protocolAn appraisal of the nitroblue tetrazolium reduction test 1 November 1973Volume 79, Issue 5Page: 758-759KeywordsBloodMyocardial infarction Issue Published: 1 November 1973 PDF DownloadLoading ...