The Lente Insulin Triad
Authors: FRED W. WHITEHOUSE
Journal: Annals of Internal Medicine (1961)

Article1 December 1961The Lente Insulin TriadWith Emphasis on the Use of "Lente Combinations"FRED W. WHITEHOUSE, M.D., F.A.C.P., WILLIAM L. LOWRIE, M.D., F.A.C.P., EARL REDFERN, M.D., JOHN B. BRYAN, M.D.FRED W. WHITEHOUSE, M.D., F.A.C.P.Search for more papers by this author, WILLIAM L. LOWRIE, M.D., F.A.C.P.Search for more papers by this author, EARL REDFERN, M.D.Search for more papers by this author, JOHN B. BRYAN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-55-6-894 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptFor the last five years the medical literature on the therapy of diabetes mellitus has dealt generously with the use of the oral hypoglycemic agents. The indications and limitations of these drugs are now clear. Their use is limited to the patient with maturity-onset diabetes. They are ineffective in the patient with growth-onset diabetes who lacks endogenous insulin. The limited applicability of the oral hypoglycemic agents has re-emphasized the importance of insulin. Insulin, when used correctly, is effective in all patients with diabetes. The proper use of insulin must be mastered by those accepting the responsibility of the care of...References1. HALLAS-MOLLERJERSILDPETERSENSCHLICHTKRULL KMKJ: Zinc insulin preparations for single daily injection. J. A. M. A. 150: 1667, 1952. CrossrefMedlineGoogle Scholar2. HALLAS-MOLLER K: The lente insulins. Diabetes 5: 7, 1956. CrossrefMedlineGoogle Scholar3. MARBLE A: Lente insulin in the treatment of diabetes mellitus. Med. Clin. N. Amer. 41: 485, 1957. CrossrefMedlineGoogle Scholar4. HAUNZ E: Clinical evaluation of lente insulin in one hundred nine diabetic patients. J. A. M. A. 159: 1611, 1955. CrossrefMedlineGoogle Scholar5. LANCASTERMURRAY WMI: Further experience with the "lente insulins." Brit. Med. J. 1: 1331, 1958. CrossrefMedlineGoogle Scholar6. SLAYTONBURROWSMARBLE RERA: Lente insulin in the treatment of diabetes. New Engl. J. Med. 253: 722, 1955. CrossrefMedlineGoogle Scholar7. PECKKIRTLEYDYKEERNST FBWRRWCE: Present status of insulin-zinc suspensions. Diabetes 3: 261, 1954. CrossrefMedlineGoogle Scholar8. WILDBERGERRICKETTS HLHT: Multiple injections of crystalline insulin in treatment of labile diabetes. J. A. M. A. 172: 655, 1960. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Detroit, MichiganRequests for reprints should be addressed to Fred W. Whitehouse, M.D., Henry Ford Hospital, Detroit 2, Michigan.*Regular or amorphous insulin is no longer produced commercially. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByThe Evolution of Insulin Glargine and its Continuing Contribution to Diabetes CareInsulin Preparations with Prolonged EffectTherapie des Typ-I-DiabetesInsulin Preparations with Prolonged Effect 1 December 1961Volume 55, Issue 6Page: 894-902KeywordsDiabetes mellitusDrugsHypoglycemicsInsulinProteinsType 2 diabetes Issue Published: 1 December 1961 PDF DownloadLoading ...