Doxorubicin in the First Trimester of Pregnancy
Authors: VICENTE GARCIA
Journal: Annals of Internal Medicine (1981)

Letters and Corrections1 April 1981Doxorubicin in the First Trimester of PregnancyVICENTE GARCIA, M.D., JESÚS SAN MIGUEL, M.D., ANTONIO LÓPEZ BORRASCA, M.D.VICENTE GARCIA, M.D.Search for more papers by this author, JESÚS SAN MIGUEL, M.D.Search for more papers by this author, ANTONIO LÓPEZ BORRASCA, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-94-4-547_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Experience with chemotherapeutic agents during human pregnancy is limited. We could find only seven references (1-5) to the use of doxorubicin during pregnancy. In all cases the administration was after the 20th week of pregnancy. There is no clinical evidence that the developing fetus was damaged in the cases published. We report here the case of a patient and her fetus in which polyhemotherapy including doxorubicin was given in the first trimester of pregnancy.A 25-year-old woman was admitted in December 1979 with complaints of sweating, weight loss, fever, and cervical and abdominal lymphadenopathy. Biopsy confirmed the...References1. KHURSIDSALEEM MM. Acute leukaemia in pregnancy. Lancet. 1978;2:534-5. Letter. CrossrefGoogle Scholar2. NEWCOMBBALDUCCITHIGPNENMORRISON MLJF. Acute leukemia in pregnancy; successful delivery after cytarabine and doxorubicin. JAMA. 1978;239:2691-2. CrossrefMedlineGoogle Scholar3. ROBOZGLEICHERWUCHAHINIANKERENYIHOLLAND JNKPTJ. Does doxorubicin cross the placenta? Lancet. 1979;2:1382-3. Letter. CrossrefMedlineGoogle Scholar4. TOBIASBLOOM JH. Doxorubicin in pregnancy. Lancet. 1980;1:776. CrossrefMedlineGoogle Scholar5. CERVANTESROZMAN FC. Adriamicina y embarazo. Sangre. 1980;25:627. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: University of Salamanca Salamanca, Spain PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byTreatment of Acute Myeloid Leukemia During PregnancyCancer chemotherapeutic agents as human teratogensSpezielle Arzneimitteltherapie in der SchwangerschaftTreatment of the pregnant mother with cancer: A systematic review on the use of cytotoxic, endocrine, targeted agents and immunotherapy during pregnancy. Part II: Hematological tumorsAdjuvant Therapy in Patients with Breast Cancer During PregnancyAntineoplastic drugsSpezielle Arzneimitteltherapie in der SchwangerschaftCombined chemotherapy and radiotherapy during conception and first two trimesters of gestation in a woman with metastatic breast cancerBreast cancer in pregnancyMammakarzinom in Schwangerschaft und StillzeitAdverse Reproductive Outcome Potential of Cancer Therapies During PregnancyCritical timing of bladder embryogenesis in an adriamycin-exposed rat fetal model: A clue to the origin of the bladderCancer in PregnancyChemotherapie und SchwangerschaftPharmacology of antineoplastic agents in pregnancyMedikamentöse Tumortherapie in der Schwangerschaft: Wann und Wie?Medikamentöse Tumortherapie in der Schwangerschaft: Wann und Wie?Chemotherapy and pregnancyPregnancy outcome in hematologic malignanciesCombination chemotherapy and radiation for stage IV breast cancer during pregnancyTreatment of an aggressive non-Hodgkin's lymphoma during pregnancy with MACOP-B chemotherapyAnthracyclines in the treatment of malignancy in pregnancy 1 April 1981Volume 94, Issue 4_Part_1Page: 547-547KeywordsBiopsyChemotherapeutic agentsFetusesFeversPregnancyWeight loss Issue Published: 1 April 1981 PDF downloadLoading ...