Hepatitis and Leukemia
Authors: JOSEPH P. FIORE
Journal: Annals of Internal Medicine (1979)

Letters and Corrections1 June 1979Hepatitis and LeukemiaJOSEPH P. FIORE, M.D.JOSEPH P. FIORE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-90-6-987 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: I wish to offer several criticisms of the paper by Barton and Conrad in the February issue (1) on possible prolonged survival of leukemic patients who contract hepatitis.The authors use SGOT elevation as the major diagnostic criterion for hepatitis but acknowledge that the causes of mild SGOT elevation in leukemia can be heterogeneous, including leukemic infiltration of the liver and chemotherapeutic drugs. The authors do not state what the mean SGOT elevation was, but apparently an SGOT concentration of 50 mU/mL (normal range, 10 to 40) for more than 1 week was considered elevated. Using such...Reference1. BARTONCONRAD JM: Beneficial effects of hepatitis in patients with acute myelogenous leukemia. Ann Intern Med 90:188-190, 1979 LinkGoogle Scholar1. KNODELLCONRADDIENSTAGBELL RMJC: Etiological spectrum of post-transfusion hepatitis. Gastroenterology 69:1278-1285, 1975 CrossrefMedlineGoogle Scholar2. SURGENORCHALMERSCONRADFRIEDEWALDGRADYHAMILTONMOSLEYPRINCESTENGLE DTMWGMJAJ: Clinical trials of hepatitis B immune globulin. Development of policies and materials for the 1972-1975 studies sponsored by the National Heart and Lung Institute. N Engl J Med 293:1060-1062, 1975 CrossrefMedlineGoogle Scholar3. SZMUNESSPRINCEGRADYMANNLEVINEFRIEDMANJACOBSJOSEPHSONRIBOTSHAPIROSTENZELSUKIVYAS WAGMREMASFKWG: Hepatitis B infection. A point-prevalence study in 15 US hemodialysis centers. JAMA 227:901-906, 1974 CrossrefMedlineGoogle Scholar4. WERNERLONDON BW: Host responses to hepatitis B infection: hepatitis B surface antigen and host proteins (editorial). Ann Intern Med 83;113-114, 1975 LinkGoogle Scholar5. ARMITAGEBURNSKENT JCT: Liver disease complicating the management of acute leukemia during remission. Cancer 41:737-742, 1978 CrossrefMedlineGoogle Scholar1. BARTONCONRAD JM: Beneficial effects of hepatitis in patients with acute myelogenous leukemia. Ann Intern Med 90:188-190, 1979 LinkGoogle Scholar1. EISENLOHR C: Neuropathologische Beobachtungen. I. Leucaemia lienalis, lymphatica et medullaris mit multiplen Gehirnnervenlähmungen. Virchows Arch [Pathol Anat] 73:56-73, 1878 CrossrefGoogle Scholar2. DOCK G: The influence of complicating diseases upon leukemia. Am J Med Sci 127:563-592, 1904 CrossrefGoogle Scholar3. PELNERFOWLERNAUTS LGH: Effects of concurrent infections and their toxins on the course of leukemia. Acta Med Scand [Suppl] 338:1-47, 1958 Google Scholar4. TIGERTTCROSBYBERGEHOWIEKRESSDANGERFIELDBASSFRANK WWTDSHJW: The virus of Venezuelan equine encephalomyelitis as an antineoplastic agent in man. Cancer 15:628-632, 1962 CrossrefMedlineGoogle Scholar5. HERSHGUTTERMANMAVLIGITMCCREDIEBURGESSMATTHEWSFREIREICH EJGKMAE: Serial studies of immunocompetence of patients undergoing therapy for acute leukemia. J Clin Invest 54:401-408, 1974 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: JOSEPH P. FIORE, M.D.Affiliations: Menorah Medical Center Kansas City, MO 64110 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byLeukemia and Liver Disease in Childhood: Clinical and Histological Evaluation 1 June 1979Volume 90, Issue 6Page: 987-988KeywordsAttentionDrugsHepatitisLiverSerum glutamic oxaloacetic transaminase ePublished: 1 December 2008 Issue Published: 1 June 1979 PDF downloadLoading ...