Pemphigus of the Larynx and Esophagus
Authors: Nikolaos G. Frangogiannis
Journal: Annals of Internal Medicine (1995)

Letters15 May 1995Pemphigus of the Larynx and EsophagusNikolaos G. Frangogiannis, Subroto Gangopadhyay, and Thomas CateNikolaos G. FrangogiannisBaylor College of Medicine, Houston, TX 77030., Subroto GangopadhyayBaylor College of Medicine, Houston, TX 77030., and Thomas CateBaylor College of Medicine, Houston, TX 77030.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-122-10-199505150-00024 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Although the oral mucosa is a common site of presentation of pemphigus vulgaris, involvement of the larynx and esophagus is rare [1, 2]. We describe a patient who presented with odynophagia and hoarseness that were found to be caused by laryngeal pemphigus, which may have been triggered by enalapril, a powerful in-vitro acantholytic agent.A 63-year-old man presented with a 3-week history of odynophagia and hoarseness. For several months he had received enalapril (10 mg orally, once daily) for treatment of hypertension, and he was receiving no other medication. His skin was intact, but severe friability of ...References1. Samy LL, Girgis IH, Wasef SA. Pharyngeal and laryngeal pemphigus. J Laryngol Otolaryngol. 1968; 82:111-21. Google Scholar2. Wood DR, Patterson JB, Orlando RC. Pemphigus vulgaris of the esophagus. Ann Intern Med. 1982; 96:189-90. Google Scholar3. Brenner S, Wolf R, Ruocco V. Drug-induced pemphigus. A survey. Clin Dermatol. 1993; 11:501-5. Google Scholar4. Ruocco V, Satriano RA, Guerrera V. Two-step pemphigus induction by ACE-inhibitors. Int J Dermatol. 1992; 31:33-6. Google Scholar5. De Angelis E, Lombardi ML, Grassi M, Ruocco V. Enalapril: a powerful in vitro non-thiol acantholytic agent. Int J Dermatol. 1992; 31:722-4. Google Scholar Author, Article, and Disclosure InformationAffiliations: Baylor College of Medicine, Houston, TX 77030. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByExploring beyond the oral mucosa in patients affected with autoimmune blistering diseases: the importance of endoscopic proceduresThe spectrum of nephrocutaneous diseases and associationsMiscellaneous Diseases of the Esophagus: Foreign Bodies, Physical Injury, and Systemic and Dermatological DiseasesEar, nose, and throat involvement in Egyptian patients with pemphigus vulgaris: a step towards a better managementMucosal manifestations of pemphigus vulgaris in ear, nose, and throat; before and after treatmentEar, nose and throat involvement in patients with pemphigus vulgaris: correlation with severity, phenotype and disease activityNON-NEOPLASTIC LESIONS OF THE LARYNXPemphigus vulgaris of the larynx and upper gastro-intestinal tract induced by radiotherapyLaryngeal pemphigus without skin manifestations and review of the literatureEar, nose and throat manifestations in pemphigus vulgarisZmiany w krtani w pęcherzycy zwykłej z dominacją zmian na błonach śluzowychCoexistence of pemphigus vulgaris and bullous pemphigoid in the upper aerodigestive tractAdverse Dermatologic Effects of Cardiovascular Drug Therapy: Part IIDevelopment of oesophageal involvement in a subject with pemphigus vulgaris: a case report and review of the literatureLarynxRamipril-induced superficial pemphigus 15 May 1995Volume 122, Issue 10Page: 803-804KeywordsDrugsEpitheliumEsophagusHypertensionImmunofluorescenceLarynxLesionsMucous membranesPharynxUlcers Issue Published: 15 May 1995 CopyrightCopyright © 1995 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...