Drawing Conclusions about Short-Term Variability in Liver Function Test Results
Authors: Liu Hong, Kaichun Wu, Daiming Fan
Journal: Annals of Internal Medicine (2008)

Letters15 July 2008Drawing Conclusions about Short-Term Variability in Liver Function Test ResultsLiu Hong, PhD, Kaichun Wu, PhD, and Daiming Fan, PhDLiu Hong, PhDFrom Institute of Digestive Diseases, Xijing Hospital, Fourth Military Medical University, Xi'an, S 710032 Shaanxi, China.Search for more papers by this author, Kaichun Wu, PhDFrom Institute of Digestive Diseases, Xijing Hospital, Fourth Military Medical University, Xi'an, S 710032 Shaanxi, China.Search for more papers by this author, and Daiming Fan, PhDFrom Institute of Digestive Diseases, Xijing Hospital, Fourth Military Medical University, Xi'an, S 710032 Shaanxi, China.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-149-2-200807150-00016 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:As Lazo and colleagues (1) report, clinicians should be aware of the high intraindividual variability in common liver tests, and practice guidelines should explicitly recommend retesting asymptomatic individuals who have abnormal liver test results. Lazo and colleagues evaluate the association of intraindividual variability with alcohol consumption; hepatitis A, B, or C serologic status; recent infection; body mass index; or sociodemographic characteristics. However, they do not clearly explain the statistical factors affecting intraindividual variability. If liver function tests are repeated as recommended, clinicians will need to know the clinical implications of intraindividual variability in liver function tests. For ...Reference1. Lazo M, Selvin E, Clark JM. Brief communication: clinical implications of short-term variability in liver function test results. Ann Intern Med. 2008;148:348-52. [PMID: 18316753] LinkGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Institute of Digestive Diseases, Xijing Hospital, Fourth Military Medical University, Xi'an, S 710032 Shaanxi, China.Disclosures: None disclosed. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoBrief Communication: Clinical Implications of Short-Term Variability in Liver Function Test Results Mariana Lazo , Elizabeth Selvin , and Jeanne M. Clark Drawing Conclusions about Short-Term Variability in Liver Function Test Results Agostino Colli and Daniele Prati Drawing Conclusions about Short-Term Variability in Liver Function Test Results Mariana Lazo , Elizabeth Selvin , and Jeanne M. Clark Drawing Conclusions about Short-Term Variability in Liver Function Test Results Gaurav Arora and George Triadafilopoulos Drawing Conclusions about Short-Term Variability in Liver Function Test Results Weekitt Kittisupamongkol Metrics 15 July 2008Volume 149, Issue 2Page: 144-145KeywordsAlcohol consumptionBody mass indexConflicts of interestHepatitis AHepatitis BHeredityLiverLiver function testsTreatment guidelines ePublished: 15 July 2008 Issue Published: 15 July 2008 Copyright & PermissionsCopyright © 2008 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...