Granulomatous Peritonitis Secondary to Corn Starch
Authors: BARBARA BATES
Journal: Annals of Internal Medicine (1965)

Case Studies1 February 1965Granulomatous Peritonitis Secondary to Corn StarchBARBARA BATES, M.D.BARBARA BATES, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-62-2-335 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptEarly in the 1950's a corn starch derivative rapidly replaced talc as the surgical glove powder of choice in this country (1). This change was brought about by the widely recognized tendency of talc to produce postoperative foreign body reactions in human tissues, manifested most often by sinus formation and most disastrously by granulomatous reactions and adhesions in the peritoneal cavity with resultant bowel obstruction (2, 3). Search began in the early 1940's for a talc substitute, and in 1947 Lee and Lehman (4) reported on the experimentally demonstrable advantages and apparent safety of a corn starch derivative later marketed...References1. LEECOLLINSLARGEN CMWTTL: A reappraisal of absorbable glove powder. Surg. Gynec. Obstet. 95: 725, 1952. MedlineGoogle Scholar2. EISEMANSEELIGWOMACK BMGNA: Talcum powder granuloma: a frequent and seriouspostoperative complication. Ann. Surg. 126: 820, 1947. CrossrefMedlineGoogle Scholar3. LICHTMANMCDONALDDIXONMANN ALJRCFFC: Talc granuloma. Surg. Gynec. Obstet. 83: 531, 1946. MedlineGoogle Scholar4. LEELEHMAN CMEP: Experiments with nonirritating glove powder. Surg. Gynec. Obstet. 84: 689, 1947. MedlineGoogle Scholar5. : Pharmaceutic and therapeutic aids, in New and Nonofficial Remedies, J. B. Lippincott Co., Philadelphia, 1951, p. 419. Google Scholar6. POSTLETHWAITMCRAEWILLIAMSDEATONCORNATZER RWJTRWWRWE: Absorbable starch glove powder. Amer. J. Surg. 78: 510, 1949. CrossrefMedlineGoogle Scholar7. SNEIERSONWOO HZP: Starch powder granuloma. A report of two cases. Ann. Surg. 142: 1045, 1955. CrossrefMedlineGoogle Scholar8. MCADAMS GB: Granulomata caused by absorbable starch glove powder. Surgery 39: 329, 1956. MedlineGoogle Scholar9. HYDENMCCLELLAN WHJT: Glove powder granuloma in peritoneal cavity. JAMA 170: 1048, 1959. CrossrefMedlineGoogle Scholar10. MAGGSREINUS RLFZ: Peritonitis, caused by surgical glove starch powder, treated with steroids. Amer. J. Surg. 98: 111, 1959. CrossrefMedlineGoogle Scholar11. MYERSDEAVERBROWN RNJMCE: Granulomatous peritonitis due to starch glove powder: a clinical and experimental study. Ann. Surg. 151: 106, 1960. MedlineGoogle Scholar12. RADKENYHUSBELL HMLMJW: Starch granuloma. The problem of surgical glove powder. Northwest Med. 60: 283, 1961. MedlineGoogle Scholar13. MELODY GF: Intestinal obstructions following gynecological operations. J. Int. Coll. Surg. 35: 283, 1961. MedlineGoogle Scholar14. WEBBREGAN DFJF: Starch powder granulomas in the peritoneal cavity. Arch. Surg. 84: 282, 1962. CrossrefMedlineGoogle Scholar15. LEHMANWILDER WBJR: Corn starch granulomatous peritonitis. J. Abdom. Surg. 4: 77, 1962. MedlineGoogle Scholar16. SAXÉNKASSINENSAXÉN LAE: Peritoneal foreign-body reaction caused by condom emulsion. Lancet 1: 1295, 1963. CrossrefMedlineGoogle Scholar17. PAINESMITH CGP: Starch granulomata. J. Clin. Path. 10: 51, 1957. CrossrefMedlineGoogle Scholar18. ISING U: Foreign-body granuloma resulting from the use of starch glove powder at surgery. Acta Chir. Scand. 120: 95, 1960. MedlineGoogle Scholar19. ZULLIG AM: Talk- und Stärkegranulome, verursacht durch chirurgische Handschuhpuder. Schweiz. Med. Wschr. 92: 1703, 1962. MedlineGoogle Scholar20. WILANDMASCICRAVER JJNBN: A comparison of talc and absorbable starch powders. Surg. Gynec. Obstet. 99: 277, 1954. MedlineGoogle Scholar21. GRAHAMJENKINS JDME: The effects of introducing certain suggested substitutes for talc into the peritoneal cavity and into wounds in experimental animals. J. Pharm. Pharmacol. 4: 392, 1952. CrossrefMedlineGoogle Scholar22. MACQUIDDYTOLLMAN ELJP: Observations on an absorbable powder to replace talc. Surgery 23: 786, 1948. MedlineGoogle Scholar23. MCADAMS GB: Personal communication. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Lexington, KentuckyFrom the Department of Medicine, University of Kentucky, College of Medicine, Lexington, Ky.Requests for reprints should be addressed to Barbara Bates, M.D., Department of Medicine, University of Kentucky, College of Medicine, Lexington, Ky. 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