Normal Serum Acid Phosphatase Levels in Osteogenesis Imperfecta
Authors: DONALD M. GINSBERG
Journal: Annals of Internal Medicine (1962)

Brief Communication1 January 1962Normal Serum Acid Phosphatase Levels in Osteogenesis ImperfectaDONALD M. GINSBERG, M.D.DONALD M. GINSBERG, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-56-1-141 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptRecent reports (1, 2) indicate that osteogenesis imperfecta may be associated with elevated acid phosphatase levels. Our experience with 11 patients having this malady forms the basis of this report.MATERIAL AND METHODThis study comprises [a] seven cases of active osteogenesis imperfecta in children with multiple recent fractures (Table 1, Cases 1-7), [b] three adults with burned-out osteogenesis imperfecta who suffered numerous fractures in childhood (Table 2, Cases 8-10), [c] the mother of a child with this disease who presented only with blue sclerae but who had never suffered a fracture (Table 3, Case 14), and [d] three other...References1. GEBALA A: Acid hyperphosphatasia in three families with osteogenesis imperfecta. Lancet 2: 1084, 1956. CrossrefGoogle Scholar2. KESSELSIGNY AWAG: Acid hyperphosphatasia in three families with osteogenesis imperfecta (Letter to the Editor). Lancet 2: 1217, 1956. CrossrefGoogle Scholar3. GEBALAROSENMUND AH: Studies of the activity of acid phosphatases in serum of children. Helv. Paediat. Acta 14: 511, 1959. MedlineGoogle Scholar4. ROSENMUND H: Untersuchungen über die saure Phosphatase Aktivität. Helv. Med. Acta Supp. 33, Vol. 20, 1953. Google Scholar5. LARONEPSTEIN-HALBERSTADT ZB: Activity of acid phosphatase in the serum of normal infants and children. Pediatrics 26: 281, 1960. MedlineGoogle Scholar6. KINGWOOTON EJID: Microanalysis in Medical Biochemistry, 3d. ed., J. & A. Churchill, Ltd., London, 1956, p. 90. Google Scholar7. WOODARD HQ: The clinical significance of serum acid phosphatase. Amer. J. Med. 27: 902, 1959. CrossrefMedlineGoogle Scholar8. JACOBSENMATIENZOFORBESROURKE JGJAAPGM: Serum acid phosphatase in osteogenesis imperfecta. Metabolism 10: 483, 1961. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Brooklyn, New YorkFrom the Department of Medicine, Beth-El Hospital, Linden Boulevard and Rockaway Parkway, Brooklyn 12, New York.Supported by a grant from the Damon Runyon Fund.Requests for reprints should be addressed to Donald M. Ginsberg, M.D., 568 E. 56th Street, Brooklyn 3, New York. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byOsteogenesis Imperfecta Associated with Multiple MyelomaSkelettveränderungen vom Typ der Osteogenesis imperfecta bei RaubkatzenVergleichende untersuchungen von “sauren” plasmaphosphatasen bei verschiedenen knochenerkrankungenMedical genetics 1961 1 January 1962Volume 56, Issue 1Page: 141-143KeywordsAcid phosphataseChildrenClinical laboratoriesHospital medicineMedical educationPhosphatases Issue Published: 1 January 1962 PDF downloadLoading ...