Tamoxifen Therapy for Metastatic Carcinoid Tumor: A Negative Study
Authors: CHARLES G. MOERTEL
Journal: Annals of Internal Medicine (1984)

Brief Reports1 April 1984Tamoxifen Therapy for Metastatic Carcinoid Tumor: A Negative StudyCHARLES G. MOERTEL, M.D., PAUL F. ENGSTROM, M.D., ALLAN J. SCHUTT, M.D.CHARLES G. MOERTEL, M.D., PAUL F. ENGSTROM, M.D., ALLAN J. SCHUTT, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-100-4-531 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptManaging patients with the carcinoid tumor, whose condition is sometimes complicated by the carcinoid syndrome, presents a difficult challenge. Surgical treatment is usually curative in early stages and even in advanced stages may provide palliation. Nonsurgical treatment, however, has been disappointing. Radiation therapy is only rarely helpful, and cytotoxic drugs have produced less than optimal results.Recent interest in the possible effectiveness of hormonal alteration has been raised by reports of the presence of estrogen receptors in carcinoid tumor (1) and of a patient who had symptomatic improvement of the carcinoid syndrome with tamoxifen therapy (2). Particularly impressive has been...References1. KESHGEGIANWHEELER AJ. Estrogen receptor protein in malignant carcinoid tumor: a report of 2 cases. Cancer. 1980;45:293-6. CrossrefMedlineGoogle Scholar2. STATHOPOULOSKARVOUNTZISYIOTIS GGJ. Tamoxifen in carcinoid syndrome [Letter]. N Engl J Med. 1981;305:52. CrossrefMedlineGoogle Scholar3. MYERSERSHLERTANNENBAUMBARTH CWMR. Tamoxifen and carcinoid tumor. Ann Intern Med. 1982;96:383. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Mayo Clinic Rochester, Minnesota American Oncologic Hospital Philadelphia, Pennsylvania. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySexual Dimorphism in Small-intestinal Neuroendocrine Tumors: Lower Prevalence of Mesenteric Disease in Premenopausal WomenPathogenesis and Clinical Management of Mesenteric Fibrosis in Small Intestinal Neuroendocine Neoplasms: A Systematic ReviewUpdate on Pathophysiology, Treatment, and Complications of Carcinoid SyndromeSmall intestinal neuroendocrine tumours and fibrosis: an entangled conundrumCarcinoid TumorsTherapeutic Options for Gastrointestinal CarcinoidsCurrent Status of Gastrointestinal CarcinoidsIntralesional interferon for the treatment of metastatic carcinoid tumoursTumoren des endokrinen SystemsPartial Remission of Carcinoid Tumor in Response to CyproheptadineStuart P. Leitner, MD, Paul Greenberg, MD, Linda A. Danieu, MD, Richard A. Michaelson, MDRegional treatment of hepatic metastases and hepatocellular carcinomaTherapy of the Malignant Carcinoid SyndromeTherapy of the Malignant Carcinoid Syndrome and Metastatic Islet Cell CarcinomaGastrointestinal Carcinoid TumoursTherapeutic Considerations for the Malignant Carcinoid SyndromeChemotherapy of metastatic carcinoid and islet cell tumors: A reviewMetastatic carcinoid tumors and the carcinoid syndrome: A selective review of chemotherapy and hormonal therapy 1 April 1984Volume 100, Issue 4Page: 531-532KeywordsCarcinoid tumorDrug therapyEstrogensMedical servicesRadiation therapy ePublished: 1 December 2008 Issue Published: 1 April 1984 PDF downloadLoading ...