Epidemic Coxsackie Virus Infection with Mixed Clinical Manifestations
Authors: Malcolm S. Artenstein, Francis C. Cadigan, Edward L. Buescher
Journal: Annals of Internal Medicine (1964)

Article1 February 1964Epidemic Coxsackie Virus Infection with Mixed Clinical ManifestationsMALCOLM S. ARTENSTEIN, FRANCIS C. CADIGAN JR., EDWARD L. BUESCHERMALCOLM S. ARTENSTEIN, FRANCIS C. CADIGAN JR., EDWARD L. BUESCHERAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-60-2-196 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptWebster defines epidemic as "common to, or affecting at the same time, many in a community" (1). Classically, epidemic infectious disease is recognized when a clinical syndrome occurs common to all affected persons. Thus, epidemics caused by measles, influenza, and smallpox viruses are readily recognized and distinguished from one another on clinical grounds. However, a single agent is not always implicated in epidemic infections with homogeneous clinical manifestations. Such situations have been encountered with increasing frequency during studies of epidemic "poliomyelitis." Johnson, Shuey, and Buescher (2) found at least seven different enteroviruses associated with paralytic and nonparalytic CNS disease occurring...References1. Webster's New Collegiate Dictionary, 2nd ed., G. & C. Merriam Co., Springfield, Massachusetts, 1953, p. 277. Google Scholar2. JOHNSONSHUEYBUESCHER RTHEEL: Epidemic central nervous system disease of mixed enterovirus etiology—1. Clinical and epidemiologic description. Amer. J. Hyg. 71: 321, 1960. MedlineGoogle Scholar3. JOHNSSON T: Family infections by Coxsackie viruses. Arch. Ges. Virusforsch. 5: 384, 1954. CrossrefMedlineGoogle Scholar4. HILLEMANWERNERSTEWART MRJHMT: Grouping and occurrence of RI (Prototype RI-67) viruses. Proc. Soc. Exper. Biol. & Med. 90: 555, 1955. CrossrefMedlineGoogle Scholar5. JOHNSONBUESCHERROGERSFUNKENBUSCHOLIU RTELNGMJWE: Epidemic central nervous system disease of mixed enterovirus etiology. II. Analysis of laboratory investigations. Amer. J. Hyg. 71: 331-341, 1960. MedlineGoogle Scholar6. ENDERS JF: The application of tissue cultures to the preparation and assay of viral antibodies. Ann. NY Acad. Sci. 58: 1072, 1954. CrossrefMedlineGoogle Scholar7. ROGERSBANKHEADCRAWFORDMEYER NGAAIPHM: Metabolic inhibition test for determination of antibodies to Group B Coxsackie viruses. Proc. Soc. Exp. Biol. Med. 98: 227, 1958. CrossrefMedlineGoogle Scholar8. MEYERJOHNSONCRAWFORDDASCOMBROGERS HMRTIPHENG: Central nervous system syndromes of "Viral" etiology. Amer. J. Med. 29: 334, 1960. CrossrefMedlineGoogle Scholar9. JOHNSONPORTNOYROGERSBUESCHER RTBNGEL: Acute benign pericarditis. Virologic study of 34 patients. Arch. Intern. Med. (Chicago) 108: 823, 1961. CrossrefMedlineGoogle Scholar10. KIBRICKBENIRSCHKE SK: Severe generalized disease (encephalomyocarditis) occurring in the newborn period and due to infection with Coxsackie virus, Group B. Pediatrics 22: 857, 1958. MedlineGoogle Scholar11. GORDONLENNETTESANDROCK RBEHRS: The varied clinical manifestations of Coxsackie virus infections. Arch. Intern. Med. (Chicago) 103: 63, 1959. CrossrefGoogle Scholar12. BAINMCLEANWALKER HWDMSJ: Epidemic pleurodynia (Bornholm disease) due to Coxsackie B-5 virus. Pediatrics 27: 889, 1961. MedlineGoogle Scholar13. SYLVEST E: Epidemic Myalgia: Bornholm Disease, translated by H. Andersen. London, Oxford University Press, 1934. CrossrefGoogle Scholar14. PICKLES WN: Sylvest's Disease (Bornholm Disease), New Eng. J. Med. 250: 1033, 1954. CrossrefMedlineGoogle Scholar15. ARTENSTEINCADIGANBUESCHER MSFCEL: Coxsackie group B virus infections in man—a study of 180 cases. In preparation. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: MALCOLM S. ARTENSTEIN; FRANCIS C. CADIGANJR.; EDWARD L. BUESCHERAffiliations: Washington, D. C.From the Department of Virus Diseases, Division of Communicable Disease and Immunology, Walter Reed Army Institute of Research, Washington, D. C.Presented in part at the Twelfth Annual Regional Meeting (District of Columbia and Maryland) of the American College of Physicians, November 5, 1960.Requests for reprints should be addressed to Captain Malcolm S. Artenstein, MC, Department of Virus Diseases, Walter Reed Army Institute of Research, Walter Reed Army Medical Center, Washington 12, D. C. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byEpidemiologyEnterovirus/Picornavirus infectionsEnterovirus InfectionsEnterovirus and Parechovirus InfectionsHERPANGINAEnterovirus and Parechovirus InfectionsGroup B Coxsackie Disease in ChildrenPerinatal Echovirus and Croup B Coxsackievirus infectionsArthritis associated with common viral infectionsVirus Infections Simulating Acute Surgical Abdominal Emergencies in PregnancyNeurological, Electroencephalographic, and Virological Findings in Febrile ChildrenNewer Viral ExanthemsViral ArthritisJAMES W. SMITH, M.D., JAY P. SANFORD, M.D., F.A.C.P.Virus-PneumonienCoxsackie group B virus infection and acute diarrhoea occurring among children in Costa Rica.Hepatitis Associated with MyocarditisClinical and Epidemiological Features of Coxsackie Group B Virus InfectionsMALCOLM S. ARTENSTEIN, M.D., FRANCIS C. CADIGAN JR., EDWARD L. BUESCHERInfectious DiseasesRecent Advances in the Diagnosis and Treatment of Viral Diseases of the Skin 1 February 1964Volume 60, Issue 2_Part_1Page: 196-203KeywordsImmunologyInfectious disease immunologyInfectious diseasesInfluenza virusesMeaslesMeningitisMyocarditisOrchitisPoliomyelitisResearch laboratories ePublished: 1 December 2008 Issue Published: 1 February 1964 PDF downloadLoading ...