Bagassosis: I. Precipitins Against Extracts of Crude Bagasse in the Serum of Patients
Authors: JOHN E. SALVAGGIO
Journal: Annals of Internal Medicine (1966)

Article1 April 1966Bagassosis: I. Precipitins Against Extracts of Crude Bagasse in the Serum of PatientsJOHN E. SALVAGGIO, M.D., HOWARD A. BUECHNER, M.D., JOHN H. SEABURY, M.D., PIERRE ARQUEMBOURG, M.D.JOHN E. SALVAGGIO, M.D.Search for more papers by this author, HOWARD A. BUECHNER, M.D.Search for more papers by this author, JOHN H. SEABURY, M.D.Search for more papers by this author, PIERRE ARQUEMBOURG, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-64-4-748 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptBagassosis is an acute respiratory disease that primarily affects workers who handle bales of "bagasse" or dried sugar cane fiber. The disease was first recognized by Blitz in 1937 (1), and since that time nearly 400 cases have been described or mentioned in the world literature (2). The clinical picture is characterized by dyspnea, fever, cough, chills, weakness, anorexia, weight loss, and at times chest pain and hemoptysis, appearing hours or weeks after exposure. Upon repeated contact with bagasse, symptoms reappear and may be associated with prolonged disability and even death.The disease has occurred with greater frequency in recent...References1. BUECHNERPREVATTTHOMPSONBLITZ HAALJO: Bagassosis—a review with further historical data, studies of pulmonary function, and results of adrenal steroid therapy. Amer. J. Med. 25: 234, 1958. CrossrefMedlineGoogle Scholar2. BUECHNERAUCOINVIGNESWEILL HAEAJH: The resurgence of bagassosis in Louisiana. J. Occup. Med. 6: 437, 1964. MedlineGoogle Scholar3. BUECHNER HA: Bagassosis—a medical enigma. J. Louisiana Med. Soc. 112: 58, 1960. MedlineGoogle Scholar4. BUECHNER HA: Bagassosis. Peculiarities of its geographical pattern and report of the first case from Peru and Puerto Rico. JAMA 174: 1237, 1960. CrossrefGoogle Scholar5. BUECHNER HA: Bagassosis: a true pneumoconiosis. Industr. Med. Surg. 31: 311, 1962. MedlineGoogle Scholar6. BUECHNERRUNDE HARH: Bagassosis—reported for the first time in laboratory workers. J. Indian Med. Prof. 10: 4664, 1963. Google Scholar7. BUECHNER HA: Unpublished material. Google Scholar8. SODEMANPULLEN WARL: Bagasse disease of the lung. New Orleans Med. Surg. J. 95: 558, 1943. Google Scholar9. REYNOLDSSTEMBRIDGE RV: Electron microscopy of bagassosis in humans. Presented before the Annual Meeting of the American Thoracic Society, Chicago, Ill., May 30, 1965. Google Scholar10. PEPYSRIDDELLCITRONCLAYTON JRWKMYM: Precipitins against extracts of hay and moulds in the serum of patients with farmer's lung, aspergillosis, asthma, and sarcoidosis. Thorax 17: 366, 1962. CrossrefGoogle Scholar11. KOBAYASHISTAHMANRANKINDICKIE MMAJHA: Antigens in moldy hay as the cause of farmer's lung. Proc. Soc. Exp. Biol. Med. 113: 472, 1963. CrossrefMedlineGoogle Scholar12. PEPYSLONGBOTTOMJENKINS JJLPA: Vegetable dust pneumoconioses. Immunologic responses to vegetable dusts and their flora. Amer. Rev. Resp. Dis. 89: 842, 1964. MedlineGoogle Scholar13. REEDSASMANBARBEE CAA: Pigeon-breeder's lung. JAMA 193: 261, 1965. CrossrefMedlineGoogle Scholar14. OUCHTERLONY O: Antigen-antibody reactions in gels. Arkiv. Kemi. Mineral. Geol. 27B: 14, 1949. Google Scholar15. LONGBOTTOMPEPYS JLJ: Pulmonary aspergillosis: diagnostic and immunological significance of antigens and C-substance in Aspergillus fumigatus. J. Path. Bact. 88: 141 1964. CrossrefMedlineGoogle Scholar16. WILLIAMS JW: Inhalation and skin tests with extracts of hay and fungi in patients with farmer's lung. Thorax 18: 182, 1963. CrossrefMedlineGoogle Scholar17. BUECHNER HA: Unpublished data. Google Scholar18. BONILLA-SOTOROSEARBESMAN ONC: Allergenic molds. Antigenic and allergenic properties of Alternaria tenius. J. Allerg. 31: 246, 1961. CrossrefGoogle Scholar19. GREGORYFESTENSTEINLACEYSKINNERPEPYSJENKINS PHGMFJP: Farmer's lung disease: The development of antigens in moulding hay. J. Gen. Microbiol. 36: 429, 1964. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: JOHN E. SALVAGGIO, M.D.; HOWARD A. BUECHNER, M.D.; JOHN H. SEABURY, M.D.; PIERRE ARQUEMBOURG, M.D.Affiliations: New Orleans, LouisianaFrom the Departments of Medicine and Microbiology (Clinical Immunology), Louisiana State University School of Medicine, and the Medical Service, Veterans Administration Hospital, New Orleans, La.This study was supported in part by research grants AI-05754 and HE-02942, U. S. Public Health Service, Bethesda, Md.Dr. Buechner was supported by a grant from the Louisiana Tuberculosis and Respiratory Disease Association, New Orleans, La.Requests for reprints should be addressed to John E. Salvaggio, M.D., 1542 Tulane Ave., New Orleans, La. 70112. 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FINK, M.D., ABE J. SOSMAN, M.D., JOSEPH J. BARBORIAK, PH.D., DONALD P. SCHLUETER, M.D., RICHARD A. HOLMES, M.D.Allergic alveolitis in a maltworkerBAGASSOSISDeep-Seated Mycotic Infections, Allergy to Fungi and MycotoxinsBagasse Disease of the Lungs — After 25 YearsPIGEON BREEDER'S LUNGImmunologic studies of pigeon breeder's diseaseDiffuse Interstitial Pulmonary FibrosisPulmonary Granulomatoses Due to Inhaled Organic Antigens 1 April 1966Volume 64, Issue 4Page: 748-758KeywordsHospital medicineIschemiaMedical servicesMicrobiologyPathogenesisPatientsPneumoconiosesPulmonary diseasesResearch grantsWeight loss ePublished: 1 December 2008 Issue Published: 1 April 1966 PDF downloadLoading ...