IMMUNITY TO TISSUE GRAFTS
Authors: PAUL W. CLOUGH
Journal: Annals of Internal Medicine (1960)

Editorial1 July 1960IMMUNITY TO TISSUE GRAFTSPAUL W. CLOUGH, M.D.PAUL W. CLOUGH, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-53-1-228 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIt has long been common knowledge that if skin is grafted on human subjects, only autografts, from the same individual, survive. Homografts, from other individuals of the same species, are rejected except when the donor and recipient are identical twins with exactly the same antigens. This has been found true of all vertebrates studied, from fish to monkeys.If some means could be found to circumvent this process of rejection of the graft, it would be a therapeutic triumph of major importance. 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