Multiple Chemical Sensitivities
Authors: Abba I. Terr
Journal: Annals of Internal Medicine (1993)

Editorials15 July 1993Multiple Chemical SensitivitiesAbba I. Terr, MDAbba I. Terr, MDStanford University Medical Center, Room S-021, Stanford, CA 94305.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-119-2-199307150-00012 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Multiple chemical sensitivities has been proposed as a name of a new disease in which the affected patient has adverse reactions when exposed to numerous items encountered under ordinary, daily conditions. The items, referred to as chemicals, include organic solvents, pesticides, paints, new carpets, household detergents, new clothing, building construction materials, and many others. Reactions consist of subjective symptoms without accompanying physical signs or biochemical abnormalities. Patients have many and varied symptoms, but the ones they report most frequently include fatigue, malaise, headache, lack of concentration, memory loss, and spaciness. Many of these patients report similar intolerances to many foods ...References1. Cullen MR. The worker with multiple chemical hypersensitivities: an overview. Occup Med. 1987; 2:655-61. Google Scholar2. Randolph TG. Human Ecology and Susceptibility to the Chemical Environment. Springfield, Illinois: Charles C Thomas, Publisher; 1962. Google Scholar3. Levin AS, Byers VS. Environmental illness: a disorder of immune regulation. Occup Med. 1987; 2:669-81. Google Scholar4. Bell IR, Miller CS, Schwartz GE. An olfactory-limbic model of multiple chemical sensitivity syndrome: possible relationships to kindling and affective spectrum disorders. Biol Psychiatry. 1992; 32: 218-42. Google Scholar5. American College of Physicians. Clinical ecology. Ann Intern Med. 1989; 111:168-78. Google Scholar6. Simon GE, Daniell W, Stockbridge H, Claypoole K, Rosenstock L. Immunologic, psychologic, and neuropsychologic factors in multiple chemical sensitivity. A controlled study. Ann Intern Med. 1993; 119: 97-103. Google Scholar7. Terr AI. Multiple chemical sensitivities: immunologic critique of clinical ecology theories and practice. Occup Med. 1987; 2:683-94. Google Scholar8. Terr AI. Environmental illness. A clinical review of 50 cases. Arch Intern Med. 1986; 146:145-9. Google Scholar9. Brodsky CM. Allergic to everything: a medical subculture. Psychosomatics. 1983; 24:731-2, 734-6, 740-2. Google Scholar10. Stewart DE, Raskin J. Psychiatric assessment of patients with 20th-century disease (total allergy syndrome). Can Med Assoc J. 1985; 133:1001-5. Google Scholar11. Black DW, Rathe A, Goldstein RB. Environmental illness: a controlled study of 26 subjects with 20th century disease. JAMA. 1990; 264:3166-70. Google Scholar12. Simon GE, Katon WJ, Sparks PJ. Allergic to life: psychological factors in environmental illness. Am J Psychiatry. 1990; 147:901-6. Google Scholar13. Brodsky CM. Psychological factors contributing to somatoform diseases attributed to the workplace. The case of intoxication. J Occup Med. 1983; 25:459-64. Google Scholar14. Terr AI. Clinical ecology in the workplace. J Occup Med. 1989; 31: 257-61. Google Scholar15. Shusterman D, Balmes J, Cone J. Behavioral sensitization to irritants/odorants after acute overexposure. J Occup Med. 1988; 30: 565-7. Google Scholar16. Dickey LD; ed. Clinical Ecology. Springfield, Illinois: Charles C Thomas, 1976. Google Scholar17. Bell IR. Clinical Ecology: A New Medical Approach to Environmental Illness. Bolinas, California: Common Knowledge Press; 1982. Google Scholar18. Rea WJ, Bell IR, Suits CW, Smiley RE. Food and chemical susceptibility after environmental chemical overexposure: case histories. Ann Allergy. 1978; 41:101-10. Google Scholar19. Root DE, Katzin DB, Schnare DW. Diagnosis and treatment of patients presenting subclinical signs and symptoms of exposure to chemicals which bioaccumulate in human tissue. Proceedings of the National Conference on Hazardous Wastes and Environmental Emergencies, 14-16 May 1985:150-3. Google Scholar Author, Article, and Disclosure InformationAffiliations: Stanford University Medical Center, Room S-021, Stanford, CA 94305.Corresponding Author: Abba I. Terr, MD, Stanford University Medical Center, Room S-021, Stanford, CA 94305. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoImmunologic, Psychological, and Neuropsychological Factors in Multiple Chemical Sensitivity: A Controlled Study Gregory E. Simon , William Daniell , Henry Stockbridge , Keith Claypoole , and Linda Rosenstock Metrics Cited byDiagnostic relevance of the determination of lymphocyte subpopulations in environmental medicineBedeutung der Bestimmung von Lymphozyten-Subpopulationen in der UmweltmedizinAssociations between chemical odor intolerance and sleep disturbances in community-living adultsPrestación de servicios sanitarios basada en la evidencia: hipersensibilidad química múltiple o intolerancia ambiental idiopáticaMultiple Chemical SensitivityEarly Life Stress, Negative Paternal Relationships, and Chemical Intolerance in Middle-Aged Women: Support for a Neural Sensitization ModelIncreased Cardiopulmonary Disease Risk in a Community-Based Sample With Chemical Odor Intolerance: Implications for Women's Health and Health-Care UtilizationDifferential Resting Quantitative Electroencephalographic Alpha Patterns in Women with Environmental Chemical Intolerance, Depressives, and NormalsTime-Dependent Sensitization of Heart Rate and Blood Pressure over Multiple Laboratory Sessions in Elderly Individuals with Chemical Odor IntoleranceA polysomnographic study of sleep disturbance in community elderly with self-reported environmental chemical odor intoleranceTime-dependent sensitization of plasma beta-endorphin in community elderly with self-reported environmental chemical odor intoleranceA preliminary investigation of chlorinated hydrocarbons and chronic fatigue syndromeMultiple chemical sensitivitiesTime-Dependent Sensitization in Animals: A Possible Model of Multiple Chemical Sensitivity in HumansMultiple chemical sensitivity or multi-organ dysesthesia 15 July 1993Volume 119, Issue 2Page: 163-164KeywordsAnxietyBehaviorClinical trialsDetoxificationDietImmune systemPollutionPrimary care physiciansSafetySchizophrenia Issue Published: 15 July 1993 Copyright & PermissionsCopyright © 1993 by American College of Physicians. 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