tbuckley/cabot-search huggingface dataset:
GOAT'S MILK IN INFANT FEEDING
Authors: William Lee Secor
Journal: JAMA (1923)

<h3>To the Editor:</h3> —The first article in the series on "The Care and Feeding of Infants" was read with much interest. I am located in the hill country of Texas, to which section many infants are sent, especially during the hot summer months. Several years ago my attention was called to the milk of the Swiss goat as being superior in the feeding of these infants, most of whom have some disturbance of the gastro-intestinal tract. We have given goat's milk a careful trial, and with such excellent results that for two years the hospital has maintained its own herd for the feeding of infants and in the Sippy treatment of ulcers. Goat's milk is normally alkaline, and is easier of digestion, forms smaller curds, and conforms more nearly to human milk than does cow's milk. The fact that the goat is almost immune to tuberculosis is a factor in
The Bad News
Authors: Marian R. Block
Journal: JAMA (1987)

"I guess I have to say this, but you're going to be all right. If this is breast cancer, it's the earliest kind we know." His words are meant to reassure, but I almost burst into tears. I am a 39-year-old physician who has just had a screening mammogram, having waited to engage in the procedure about as long as a physician who recommends it to her patients can wait. My surgeon is the most trustworthy I know, someone kind and thoughtful, a superb clinician, a good communicator. There is no mass and he wishes to review the films with the radiologist before making the decision as to whether surgery is necessary. But I am a student of the medical interview. I know surgery will be recommended. I think over and over, what is it about his words that is so upsetting to me? I try to dissect their meaning.
Serum Alanine Aminotransferase of Donors in Relation to the Risk of Non-A,Non-B Hepatitis in Recipients
Authors: Richard D. Aach, Wolf Szmuness, James W. Mosley, F. Blaine Hollinger, Richard A. Kahn, Cladd E. Stevens, Virginia M. Edwards, Jochewed Werch
Journal: New England Journal of Medicine (1981)

Original Article from The New England Journal of Medicine — Serum Alanine Aminotransferase of Donors in Relation to the Risk of Non-A,Non-B Hepatitis in Recipients — The Transfusion-Transmitted Viruses Study
Anti-Ischemic and Anti-Anginal Effects of Thoracic Epidural Anesthesia Versus Those of Conventional Medical Therapy in the Treatment of Severe Refractory Unstable Angina Pectoris
Authors: Karin Olausson, Helga Magnusdottir, Leon Lurje, Bertil Wennerblom, Håkan Emanuelsson, Sven-Erik Ricksten
Journal: Circulation (1997)

Background Cardiac sympathetic blockade by thoracic epidural anesthesia (TEA) dilates stenotic coronary arteries and has been used to control pain in patients with unstable angina. The aim of the present study was to evaluate the potential anti-ischemic effects of cardiac sympathetic blockade by TEA in severe, refractory, unstable angina. Methods and Results Forty patients with unstable angina refractory to standard anti-anginal therapy were randomized to receive either continuous epidural infusion of bupivacaine (TEA, Th1 to Th5) or to standard anti-anginal therapy including β-blockers, calcium antagonists, aspirin, heparin, and nitroglycerin infusion (control group). The primary end points were number of anginal attacks and severity of myocardial ischemia assessed by 48-hour ambulatory Holter monitoring. The incidence of myocardial ischemia was lower in the TEA group (22% versus 61%; P &lt;.05). The number of ischemic episodes per patient was 1.0±0.6 in the TEA group and 3.6±0.9 in the control group ( P &lt;.05). The episode duration per patient was 4.1±2.5 minutes and 19.7±6.2 minutes in the TEA and the control groups, respectively ( P &lt;.05). The mean area-under-the-ST-time-curve was 6.8±4.3 and 32.2±14.3 (mm · min) in the TEA and the control groups, respectively ( P &lt;.05). Fifteen anginal attacks were recorded in the control group and one attack in the TEA group (0.83±0.21 versus 0.06±0.06/patient, respectively, P &lt;.01). Conclusions The anti-ischemic and anti-anginal effects of continuous TEA are superior to those of conventional therapy in the treatment of refractory unstable angina.
ELECTROSURGICAL OR SURGICAL DIATHERMY SNARE
Authors: Joseph Prenn
Journal: JAMA (1928)

The snare is made of metal, but the stylet or cannula is insulated on the inside, as is also the block that contains the electric post, as well as the head of the screw that holds the wire. An interesting feature is the insulated wire used. The insulation is off on the distal or cutting side and is equivalent to a very fine cutting edge. The tissue that is to remain is thus protected by the insulation while the cutting electric current is facing that which is to be removed. The same principle may be applied to other cutting instruments that are used in electro-surgery. It is to be used as a knife, the wire loop being moved toward the operator, or as a fixed loop, the whole instrument being moved either way. 536 Commonwealth Avenue.
Comparison of Hemodialysis with Peritoneal Dialysis as a Means of Maintaining Otherwise Terminal Uremic Patients.
Authors: Milton E. Rubini
Journal: Annals of Internal Medicine (1966)

s1 May 1966Comparison of Hemodialysis with Peritoneal Dialysis as a Means of Maintaining Otherwise Terminal Uremic Patients.Milton E. Rubini, M.D. (Associate), Albert Sokol, M.D., Sanford Gaynor, M.D., David Edelbaum, M.D., Jeanne McCray, R.N., Sybil GordonMilton E. Rubini, M.D. (Associate)Search for more papers by this author, Albert Sokol, M.D.Search for more papers by this author, Sanford Gaynor, M.D.Search for more papers by this author, David Edelbaum, M.D.Search for more papers by this author, Jeanne McCray, R.N.Search for more papers by this author, Sybil GordonSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-64-5-1181_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptLife has been maintained by chronic dialysis techniques for 4 months or longer in 20 otherwise terminal uremic patients who required one or more dialyses per week. (Peritoneal dialysis for 86 patient months; hemodialysis for 98 patient months.) This report compares operational efficiency and clinical results obtained by the two techniques. The major criterion for selection was severe chemical uremia with disabling symptoms, although incidence and severity of hypertension and anemia was similar in both groups.Of the 13 peritoneal dialysis patients 9 died despite therapy, invariably with or of infection. Three were transferred to hemodialysis or transplanted and one... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Los Angeles, California PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 May 1966Volume 64, Issue 5Page: 1181-1181KeywordsAnemiaHypertensionMedical dialysisPeritoneal dialysis Issue Published: 1 May 1966 PDF downloadLoading ...
Allergy to Mace
Authors: Neal S. Penneys
Journal: JAMA (1977)

To the Editor.—  Dr Frazier's article (236:2526, 1976) is not the second reported instance of allergic contact dermatitis to chemical mace. In 1969, we reported several cases of allergic contact dermatitis to chloroacetophenone, the active ingredient in chemical mace. 1 Furthermore, we evaluated the sensitizing potential of this compound and studied cross-reactivities to related chemical compounds. We agree with Dr Frasier's conclusions that physicians should be aware of this undesirable complication which may be associated with the use of chemical mace.
Genomewide DNA methylation analysis reveals novel targets for drug development in mantle cell lymphoma
Authors: Violetta V. Leshchenko, Pei-Yu Kuo, Rita Shaknovich, David T. Yang, Tobias Gellen, Adam Petrich, Yiting Yu, Yvonne Remache, Marc A. Weniger, Sarwish Rafiq, K. Stephen Suh, Andre Goy, Wyndham Wilson, Amit Verma, Ira Braunschweig, Natarajan Muthusamy, Brad S. Kahl, John C. Byrd, Adrian Wiestner, Ari Melnick, Samir Parekh
Journal: Blood (2010)
Spatial domain analysis of late ventricular potentials. Intraoperative and thoracic correlations.
Authors: D Lacroix, P Savard, M Shenasa, W Kaltenbrunner, R Cardinal, P Pagé, D Joly, D Derome, R Nadeau
Journal: Circulation Research (1990)

For investigation of late potentials seen on the signal-averaged electrocardiogram, intracardiac and thoracic distributions of terminal activity were analyzed in 16 patients undergoing cryosurgery for ventricular tachycardia after remote myocardial infarction. The body surface potentials measured with 63 time-averaged unipolar leads were compared with epicardial and endocardial potential maps in six patients without and 10 patients with bundle-branch block. Intracardiac post-QRS activity, defined as extending beyond the thoracic QRS offset, was found in five of six patients without bundle-branch block (83%) and in five of 10 patients with bundle-branch block (50%), corresponding to 4 +/- 5% of the total number of electrograms in each patient. Fragmentation, double deflections, and single deflections were observed in 27%, 34%, and 39%, respectively, of these post-QRS electrograms. Post-QRS activation patterns that were stable from beat to beat showed slow propagation around or within areas of conduction block. Post-QRS activity was most often observed on both epicardial and endocardial surfaces (five of 10 patients). In the six patients without post-QRS activity, an area of late activity displaying low-amplitude deflections that were masked by the terminal activation of the normal myocardium was identified. Isopotential maps of the high-pass-filtered (55-Hz) thoracic and intracardiac signals demonstrated a close spatial correlation between the location, amplitude, and orientation of the potential extrema observed over the thoracic, epicardial, or endocardial surfaces during post-QRS activity. The thoracic patterns were generally dipolar with close extrema for anteroseptal or apical sites of post-QRS activity and more distant extrema for other sites.(ABSTRACT TRUNCATED AT 250 WORDS)
Preemployment Medical Examinations-Reply
Authors: T. Forrest Fisher
Journal: JAMA (1982)

<h3>In Reply.—</h3> In my response to Dr Crumrine, I stated, "The company policy should be developed with physician input and full consideration of [EEOC] regulations and EEOC decisions on similar cases." The employer has full responsibility for the safety and health of the worker in the workplace. Therefore, the company should have a policy on the placement of employees in the workplace. I further stated, "The decision on waiving restrictions for the employee on the application for employment with a definite inguinal hernia and a moderate-sized defect rests with the examining physician who should be guided by company guidelines." I agree that a physician should not permit nonmedical considerations, especially laws that are directed to the employer, to modify his medical judgment; however, the physician should not function in a vacuum, isolated from the rules and regulations of society. I also agree that a physician should maintain medical confidentiality when
Lifebox: the difference a donation makes
Authors: J. Feinmann
Journal: BMJ (2012)

Atul Gawande, writer, and surgeon at Brigham and Women’s Hospital in Boston, US, is also chair of Lifebox, chosen as the <i>BMJ</i>’s Christmas charity. <b>Jane Feinmann</b> asked him just what a <i>BMJ</i> reader donation means
Chinese authorities on alert as SARS breaks out again
Authors: Jane Parry
Journal: BMJ (2004)

China is on high alert following a fresh outbreak of severe acute respiratory syndrome (SARS). The index case is a 26 year old female laboratory researcher from Anhui province who worked for two weeks at the Chinese National Institute of Virology in Beijing, which is known to be investigating the SARS coronavirus.

The researcher, who developed symptoms of SARS on 25 March, subsequently infected her mother, who died, and a 20 year old nurse in a Beijing hospital where she was being treated. In turn the nurse is suspected of having infected her mother, father, aunt, and a fellow patient. A 31 year old laboratory researcher who also worked at the virology research laboratory is also suspected of having …
Inhalation exposure system used for acute and repeated-dose methyl isocyanate exposures of laboratory animals.
Authors: B Adkins, R W O'Connor, J M Dement
Journal: Environmental Health Perspectives (1987)

Laboratory animals were exposed by inhalation for 2 hr/day (acute) or 6 hr/day (four consecutive days, repeated dose) to methyl isocyanate (MIC). Exposures were conducted in stainless steel and glass inhalation exposure chambers placed in stainless steel, wire mesh cages. MIC was delivered with nitrogen via stainless steel and Teflon supply lines. Chamber concentrations ranged from 0 to 60 ppm and were monitored continuously with infrared spectrophotometers to 1 ppm and at 2-hr intervals to 20 ppb with a high performance liquid chromatograph equipped with a fluorescence detector. Other operational parameters monitored on a continuous basis included chamber temperature (20-27 degrees C), relative humidity (31-64%), static (transmural) pressure (-0.3 in.), and flow (300-500 L/min). The computer-assistance system interfaced with the inhalation exposure laboratory is described in detail, including the analytical instrumentation calibration system used throughout this investigation.
Endoscopic ultrasound-guided antegrade dilation of a stenosed hepaticojejunostomy
Authors: A. Bapaye, N. Dubale
Journal: Endoscopy (2013)

Endoscopic dilation of a strictured hepaticojejunostomy can be performed through an access or afferent loop using a balloon enteroscope or a pediatric colonoscope; however, these can be cumbersome procedures. Alternatively, a percutaneous approach may be utilized, but is associated with significant morbidity because of the requirement for external drainage catheters. Recently, endoscopic ultrasound (EUS)-guided biliary drainage (EUS-BD) or therapy has been successfully used when retrograde access has failed [1] [2] [3]. Here we describe a case involving a stenosed hepaticojejunostomy that was treated by EUS-guided antegrade balloon dilation. To the best of our knowledge, this is only the second such case reported in the literature [4].
Comparative cognitive studies, not folk phylogeny, please
Authors: Colin Allen
Journal: Behavioral and Brain Sciences (1996)

Abstract Barresi &amp; Moore (B&amp;M) provide a useful tool for the comparative study of social cognition that could, however, be improved by more subtle analysis of first person information about intentional relations. Knowledge of misrepresentation also needs to be better handled within the theory. I urge skepticism about B&amp;M's sweeping phylogenetic claims.
In vivo depletion of CD25+ cells prior to LRAST increases therapeutic efficacy in a murine melanoma model
Authors: Julia R Kovács, Peter Rose, Louis Boon, Rudolf A Hatz, Hauke Winter, Natasja K van den Engel
Journal: Journal for ImmunoTherapy of Cancer (2014)

Meeting abstracts Lymphodepletion, immune reconstitution and active- specific tumor cell vaccination (LRAST) have proven to benefit the activation of tumor-specific T cells in mice during homeostatic proliferation. Immunoregulatory mechanisms like the induction of regulatory T cells may counteract
Vitamin D and Myocardial Infarction
Authors: V. Linden
Journal: BMJ (1974)

A detailed investigation was carried out into the consumption of vitamin D from different sources in patients who had suffered from myocardial infarction, angina pectoris, and degenerative joint diseases. Randomly selected controls of the same ages and sex were drawn from the Central Bureau of Statistics. The consumption was significantly higher in infarction patients. A daily intake of 30 μg may be the critical level. Student9s t test for trend showed increasing probability of myocardial infarction with increasing intake of vitamin D, and more infarction patients than controls had a history of kidney stone. Long-term high consumption of vitamin D may be a precipitating cause of myocardial infarction.
LAW AND MEDICINE
Authors: Hugo A. Frank
Journal: JAMA (1970)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
TREATMENT OF PURULENT OPHTHALMIA.
Authors: GEO. H. PRICE
Journal: JAMA (1907)

By purulent ophthalmia we usually understand that form of conjunctivitis characterized by a flow of pus and due to gonococcic infection, and from this standpoint I will discuss this question. The forms of purulent conjunctivitis of gonococcic origin, which are the most common, are ophthalmia neonatorum, the purulent ophthalmia of the adult, and a third form, quite rare in some localities, namely, the purulent conjunctivitis of young boys and girls. <h3>PROPHYLAXIS.</h3> As "an ounce of prevention is worth a pound of cure," I shall presume that we are apprised of the possibility of infection in any given case, either remotely or immediately, and hence shall refer to the prevention, if possible, in any such given case. Prophylaxis in ophthalmia neonatorum is so well known and thoroughly established that simple reference to this important procedure at once suggests Credé's method, introduced in his practice in the Lying-in Hospital of Leipzig in
Over-the-counter Medication Use Among US Preschool-age Children
Authors: M D Kogan, G Pappas, S M Yu, M Kotelchuck
Journal: JAMA (1994)

<h3>Objective.</h3> —To estimate the prevalence of recent over-the-counter (OTC) medication use in a national sample of preschool-age children. <h3>Design.</h3> —Follow-up survey of a nationally representative sample of 3-year-old children in the US population by telephone or personal interview. <h3>Participants.</h3> —A total of 8145 children whose mothers were interviewed for the 1991 Longitudinal Follow-up to the National Maternal and Infant Health Survey. <h3>Main Outcome Measures.</h3> —Report of any OTC medications given in the past 30 days and the type of medications that the child received. <h3>Results.</h3> —During the past 30 days, 53.7% of all 3-year-old children in the United States were given some OTC medications. Among OTC medication users, the most common medications reported were Tylenol (66.7%) and cough or cold medicine (66.7%). Most respondents reported that recent child illness episodes (70%) were treated with OTC medications. After adjustment for recent child illness, women who were white (odds ratio [OR], 1.32; 95% confidence interval [CI], 1.13 to 1.55), were more educated (OR, 1.58; 95% CI, 1.24 to 2.00), and had higher incomes (OR, 1.75; 95% CI, 1.33 to 2.30) were more likely to have given their child OTC medications. Women without health insurance were also more likely to have given OTC medications (OR, 1.27; 95% CI, 1.04 to 1.55). Provider visits, but not telephone calls, were associated with a reduction in OTC medication usage. <h3>Conclusions.</h3> —Over-the-counter medications are an important component of health care for treating illness in US preschool-age children. The high prevalence of use has occurred despite the dearth of scientific proof for the effectiveness of certain classes of OTC medications and the risks associated with improper use. (<i>JAMA</i>. 1994;272:1025-1030)
OBSERVATIONS ON AN EPIDEMIC OF BRONCHOPNEUMONIA IN OMAHA
Authors: D. DUNN
Journal: JAMA (1918)

Late in September and in the early days of October, a respiratory affection corresponding somewhat closely to the descriptions given of "Spanish influenza" appeared in Omaha. October 3 and 4, a large number of people congregated in the theaters, stores and streets, incident to the civic parades and other functions of the Aksarben festival, which yearly brings huge crowds to Omaha. October 5 and 6, the disease attained the proportions of an epidemic. We also have information that a considerable number of cases appeared among the troops in Fort Omaha on the second day following the Aksarben. The morbidity curve showing the influence of "crowds" on the outbreak of the epidemic is significant (Chart 1). <h3>THE NATURE OF THE EPIDEMIC</h3> Clinically, the disease was characterized by a more or less sudden onset, usually without definite prodromes. Headache, generally severe, was almost constant and commonly associated with backache, bone-ache and general
Indian paediatrician has been two years in prison without trial
Authors: G. Mudur
Journal: BMJ (2009)

An Indian doctor whose achievements in community health have been recognised by the international medical world and whose personal sacrifices have been cited by academics in medical schools across India will complete two years in prison on 14 May this year.

On Monday 4 May India’s Supreme Court asked the central Indian state of Chhattisgarh to respond within two weeks to a petition for bail from Binayak Sen, a paediatrician and civil rights activist, who was arrested in 2007 after an allegation that he had carried letters for armed Maoist rebels. Dr Sen has asserted that the allegation is false, and the charge against him remains unproved, despite numerous hearings in a lower court in …
A cost-benefit analysis of endoscopy reporting methods: handwritten, dictated and computerized
Authors: M. Groenen, S. Ajodhia, J. Wynstra, W. Lesterhuis, E. van de Weijgert, E. Kuipers, R. Ouwendijk
Journal: Endoscopy (2009)

Gastrointestinal endoscopy investigations are frequently requested by gastroenterologists, general practitioners and other physicians. In addition to the classic methods of report writing, several electronic endoscopic report systems are currently available. The aim of the study was to evaluate the costs of three different ways of producing reports; by hand, by dictation, or by computer.Three methods of report writing were compared, with special attention to costs. The endoscopy process was analyzed, from arrival of the patient to sending the report to the referring doctor, and including production of endoscopic images or video, logging of used endoscopes and their disinfection, and storage costs for endoscopy data.During the first 5 years, the mean costs per procedure were Euro 4.78 for handwritten, Euro 6.39 for dictated and Euro 8.90 for computerized reports. Due to depreciation, after this initial period, the respective costs declined to Euro 4.37, Euro 5.20 and Euro 5.13, respectively. Despite high initial costs, a cost-benefit analysis already revealed a financial benefit from a computerized system after 3 years.The electronic production of an endoscopic report turned out to be the most expensive way of report writing during the first 5 years, due to high initial costs. After 5 years the costs of the different systems were comparable with each other. Cost-benefit analysis showed a positive financial benefit for computerized reports after 3 years.