Nephrogenic Diabetes Insipidus Due to Sarcoidosis Without Hypercalcemia
Authors: FRED PANITZ
Journal: Annals of Internal Medicine (1965)

Case Studies1 January 1965Nephrogenic Diabetes Insipidus Due to Sarcoidosis Without HypercalcemiaFRED PANITZ, JAMES H. SHINABERGERFRED PANITZSearch for more papers by this author, JAMES H. SHINABERGERSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-62-1-113 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptPolyuria and polydipsia occurring in sarcoidosis has been previously described as the result of two entirely different pathogenetic mechanisms: [1] the production of primary or vasopressin-sensitive diabetes insipidus by discrete sarcoid lesions in the hypothalamic region, and [2] the occurrence of polyuria with renal failure and specific tubular lesions that prevent the concentration of urine, due to hypercalcemia and unresponsive to vasopressin.The purpose of this case presentation is to record the occurrence of diabetes insipidus not due to these previously reported mechanisms in a patient in whom the diagnosis of generalized sarcoidosis was established by typical X-ray findings, biopsies...References1. 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Author, Article, and Disclosure InformationAuthors: FRED PANITZ; JAMES H. SHINABERGERAffiliations: USA (MC) Heidelberg, GermanyFrom U. S. Army Hospital, Heidelberg, Germany.Requests for reprints should be addressed to Fred Panitz, M.D., 408 First Ave., New York, N. Y. 10010. 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