Rheumatic Fever in Children and Adolescents: A Long-term Epidemiologic Study of Subsequent Prophylaxis, Streptococcal Infections, and Clinical Sequelae: VI. Clinical Features of Streptococcal Infections and Rheumatic Recurrences
Authors: ALVAN R. FEINSTEIN
Journal: Annals of Internal Medicine (1964)

Article1 February 1964Rheumatic Fever in Children and AdolescentsVI. Clinical Features of Streptococcal Infections and Rheumatic RecurrencesALVAN R. FEINSTEIN, M.D., MARIO SPAGNUOLO, M.D., HARRISON F. WOOD, M.D., ANGELO TARANTA, M.D., ESTHER TURSKY, R.N., EDITH KLEINBERG, B.S.ALVAN R. FEINSTEIN, M.D., MARIO SPAGNUOLO, M.D., HARRISON F. WOOD, M.D., ANGELO TARANTA, M.D., ESTHER TURSKY, R.N., EDITH KLEINBERG, B.S.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-60-2-68 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptWhen a large group of children and adolescents is examined repetitively at monthly intervals after an attack of acute rheumatic fever, three main kinds of clinical events may be anticipated: [1] streptococcal infections, [2] recurrences of rheumatic fever, and [3] changes in cardiac status. A population of 431 young rheumatic patients, in whom these events could be observed, was originally assembled for long-term study of the antistreptococcal and antirheumatic effectiveness of three prophylactic regimens. The results of the prophylaxis study, and some selected correlations of the recurrent streptococcal and rheumatic inflammation, have been reported elsewhere (1-5).Despite the continuous use...References1. WOODSIMPSONFEINSTEINTARANTASTOLLERMAN HFRARAGH: Rheumatic fever in children and adolescents: A long-term Epidemiologic study of subsequent prophylaxis, streptococcal infections, and clinical Sequelae. I. Description of the investigative techniques and of the population studied. Ann. Intern. Med. (Feb. Supp.): 6, 1964. LinkGoogle Scholar2. GAVRINTURSKYALBAMFEINSTEIN JBEBAR: Ibid. II. Maintenance and preservation of the population. Ibid., p. 18. Google Scholar3. WOODFEINSTEINTARANTAEPSTEINSIMPSON HFARAJR: Ibid. III. 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Author, Article, and Disclosure InformationAffiliations: Irvington-on-Hudson, New YorkFrom Irvington House, Irvington-on-Hudson, New York, and the Departments of Medicine and Pediatrics, New York University School of Medicine, New York.This work was supported in part by the National Heart Institute grant H-1595 (C-1-8), American Heart Association, New York Heart Association, Westchester Heart Association, and Wyeth Laboratories.Drs. Feinstein and Wood are currently with the Department of Internal Medicine and the Department of Pediatrics, respectively, Yale University School of Medicine, New Haven, Connecticut.Requests for reprints should be addressed to Alvan R. Feinstein, M.D., Department of Internal Medicine, Yale University School of Medicine, 333 Cedar Street, New Haven 11, Connecticut. 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Classification of Human Disease by Clinical BehaviorALVAN R. FEINSTEIN, M.D.Rheumatic Fever in Children and Adolescents A Long-term Epidemiologic Study of Subsequent Prophylaxis, Streptococcal Infections, and Clinical Sequelae V. Relation of the Rheumatic Fever Recurrence Rate per Streptococcal Infection to Pre-existing Clinical Features of the PatientsANGELO TARANTA, M.D., EDITH KLEINBERG, B.S., ALVAN R. FEINSTEIN, M.D., HARRISON F. WOOD, M.D., ESTHER TURSKY, R.N., RITA SIMPSON, B.A. 1 February 1964Volume 60, Issue 2_Part_2Page: 68-86KeywordsAdolescentsChildrenHeartInflammationPediatricsProphylaxisRheumatic feverStreptococcal infections Issue Published: 1 February 1964 PDF downloadLoading ...