Anabolic Hormones in Hyperparathyroidism
Authors: RICHARD L. LANDAU
Journal: Annals of Internal Medicine (1965)

Article1 June 1965Anabolic Hormones in HyperparathyroidismWith Observations on the General Catabolic Influence of Parathyroid Hormone in ManRICHARD L. LANDAU, M.D., ATTALLAH KAPPAS, M.D.RICHARD L. LANDAU, M.D.Search for more papers by this author, ATTALLAH KAPPAS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-62-6-1223 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe studies reported here were prompted by efforts to ameliorate or control the metabolic abnormalities of a patient with hyperparathyroidism due to a functional disseminated parathyroid carcinoma. The impressive loss of bone substance and the concomitant soft tissue wasting in this patient suggested the possibility that treatment with anabolic hormones might ameliorate or reverse these changes. He received, therefore, two short courses of pituitary growth hormone and testosterone propionate for a month. This therapy resulted in a significant shift in the biochemical abnormalities toward normal and thus a more favorable clinical outlook. Anabolic sex hormones (testosterone and estradiol) also diminished...References1. LANDAULUGIBIHL RLK: The effect of dietary protein on the catabolic influence of progesterone. J. Clin. Endocr. 21: 1345, 1961. CrossrefGoogle Scholar2. CONWAY EJ: Microdiffusion Analysis. Crosby and Lickwood and Sons, Ltd., London, 1950. Google Scholar3. CLARKCOLLIP EPJB: A study of the Tisdall method for the determination of blood serum calcium with a suggested modification. J. Biol. Chem. 63: 461, 1925. CrossrefGoogle Scholar4. LAZARLANDAUKAPPAS AWRLA: Metastatic carcinoma of parathyroid and persistent hyperparathyroidism. Arch. Path. (Chicago) 72: 484, 1961. MedlineGoogle Scholar5. 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KEYSBROZEKHENSCHELLMICHELSONTAYLOR AJAOHL: The Biology of Human Starvation. University of Minnesota Press, Minneapolis, 1950. CrossrefGoogle Scholar12. BEGG RW: Tumor-host relations, in Advances in Cancer Research. Academic Press, Inc., New York, 1958, p. 1. CrossrefGoogle Scholar13. RASMUSSENSALLISFANGDELUCAYOUNG HJMHFR: Parathyroid hormone and anion uptake in isolated mitochondria. Endocrinology 74: 388, 1964. CrossrefMedlineGoogle Scholar14. KLEINALBERTSENCURTISS LKPH: Urinary hydroxyproline in hyperparathyroidism: a study of three cases with and without bone lesions. Metabolism 11: 1023, 1962. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Chicago, IllinoisFrom the Department of Medicine, the Argonne Cancer Research Hospital (operated by the University of Chicago for the United States Atomic Energy Commission), and the Clinical Research Center (FR-55), the University of Chicago, Chicago, Ill.This study was supported in part by Grant-in-Aid A-1528 from the National Institute of Arthritis and Metabolic Diseases of the National Institutes of Health, U. S. Public Health Service, Bethesda, Md.Requests for reprints should be addressed to Richard L. Landau, M.D., The University of Chicago, Department of Medicine, 950 East 59th Street, Chicago, Ill. 60637.*Obtained from the National Institutes of Health through the courtesy of Dr. A. E. Wilhelmi.†A specially purified preparation obtained through the kindness of Dr. Glenn Irwin from Eli Lilly and Company was administered to Patient D. H. Commercial Parathormone (Lilly) was administered to Patients A. L. and R. I. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDietary Approaches to Kidney DiseasesIs PTH Associated with Lipid Metabolism?Parathyroid Hormone: A Uremic ToxinNeuromuscular manifestations of electrolyte disordersHormonal Modifiers of Mineral Metabolism Other Than Parathyroid Hormone, Vitamin D, and CalcitoninDisorders of Mineral Metabolism in MalignancyEffect of Androgens on Bone, Calcium, and Phosphorus MetabolismCancer in ManSerum parathyroid hormone levels and serum calcium levels from birth to senescenceAction of androgens and related substances on mineral metabolism and boneTREATMENT WITH ŒSTROGENS OF PRIMARY HYPERPARATHYROIDISM IN POST-MENOPAUSAL WOMENThe Effect of Oral Contraceptives on Calcium AbsorptionRenal effects of a new anabolic steroid (29'038-Ba) in old ageThyrocalcitonin, osteoporosis and osteolysis 1 June 1965Volume 62, Issue 6Page: 1223-1233KeywordsEstradiolHormonesHospital medicineHyperparathyroidismParathyroid hormonePropionatesProteinsSex hormonesSoft tissuesTestosterone Issue Published: 1 June 1965 PDF downloadLoading ...