Crohn Disease and the Myelodysplastic Syndrome
Authors: Kirsten Muri Boberg
Journal: Annals of Internal Medicine (1995)

Letters1 March 1995Crohn Disease and the Myelodysplastic SyndromeKirsten Muri Boberg, Lorentz Brinch, and Morten VatnKirsten Muri BobergRikshospitalet, 0027 Oslo, Norway.Search for more papers by this author, Lorentz BrinchRikshospitalet, 0027 Oslo, Norway.Search for more papers by this author, and Morten VatnRikshospitalet, 0027 Oslo, Norway.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-122-5-199503010-00023 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:An association was suggested to exist between the myelodysplastic syndromes and Crohn disease on the basis of concomitant finding of these disorders in a series of four patients [1]. Three of these patients had clonal abnormalities of chromosome 20 in the bone marrow cells. The potential role of immune dysfunction as a common pathogenetic factor of the myelodysplastic syndromes and inflammatory bowel disease was also discussed.We describe a 70-year-old man with a 20-year history of irritable bowel disease who presented with signs of a hematologic disorder. Symptoms of irritable bowel disease were mild until October 1991, ...References1. Eng C, Farraye FA, Shulman LN, Peppercorn MA, Krauss CM, Connors JM, et al. The association between the myelodysplastic syndromes and Crohn disease. Ann Intern Med. 1992; 117:661-2. Google Scholar2. Bennett JM, Catovsky D, Daniel MT, Flandrin G, Galton DA, Gralnick HR, et al. Proposals for the classification of the myelodysplastic syndromes. Br J Haematol. 1982; 51:189-99. Google Scholar3. Mufti GJ. Chromosomal deletions in the myelodysplastic syndrome. Leuk Res. 1992; 16:35-41. Google Scholar4. Nielsen B, Thiede T. The myelodysplastic syndrome or preleukemia. Ugeskr Laeger. 1983; 145:1377-9. Google Scholar5. Kildebo S, Breckan R, Nordgaard K, Burhol PG, Jorde R for the Northern Norway Gastroenterology Society. The incidence of Crohn's disease in northern Norway from 1983 to 1986. Scand J Gastroenterol. 1989; 24:1265-70. Google Scholar Author, Article, and Disclosure InformationAuthors: Kirsten Muri Boberg; Lorentz Brinch; Morten VatnAffiliations: Rikshospitalet, 0027 Oslo, Norway. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byHematological malignancies in chronic inflammatory bowel diseases: report of five cases and review of the literatureSystematic review: managing anaemia in Crohn's diseaseCONCURRENT DEVELOPMENT OF CROHN DISEASE AND MYELODYSPLASTIC SYNDROME IN A CHILD: Case Report and Literature ReviewDevelopment of Crohn disease in patients with myelodysplastic syndrome : report of two childrenRare Extraintestinal Manifestations of Inflammatory Bowel DiseaseConcurrent Inflammatory Bowel Disease and Myelodysplastic SyndromesThe Association Between Crohn Disease and the Myelodysplastic Syndromes: Report of 3 Cases and Review of the LiteratureCrohn's Disease and the Myelodysplastic SyndromeMaladies systémiques au cours des syndromes myélodysplasiques 1 March 1995Volume 122, Issue 5Page: 395KeywordsBone marrowBone marrow cellsCrohn's diseaseErythropoiesisInflammatory bowel diseaseMegaloblastic anemiaMyelodysplastic syndromesPathogensPlateletsSystemic diseases ePublished: 15 August 2000 Issue Published: 1 March 1995 Copyright & PermissionsCopyright © 1995 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...