Antipsychotics in Adults With Schizophrenia: Does Sponsorship of Research Articles Affect the Findings?
Authors: Lisa Hartling, Amanda S. Newton, Serdar Dursun
Journal: Annals of Internal Medicine (2013)

Letters5 March 2013Antipsychotics in Adults With Schizophrenia: Does Sponsorship of Research Articles Affect the Findings?Lisa Hartling, PhD, Amanda S. Newton, RN, PhD, and Serdar Dursun, MD, PhDLisa Hartling, PhDFrom University of Alberta, Edmonton, Alberta, Canada.Search for more papers by this author, Amanda S. Newton, RN, PhDFrom University of Alberta, Edmonton, Alberta, Canada.Search for more papers by this author, and Serdar Dursun, MD, PhDFrom University of Alberta, Edmonton, Alberta, Canada.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-158-5-201303050-00015 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:A strong body of evidence supports Dr. Finucane's observation that sponsorship of research articles has been shown to affect reported results. In particular, evidence shows that industry-sponsored studies may give results that support the industry's product (1). An important task for systematic reviewers is to explore variables that may affect the validity of the reported results, including the source of funding.In our systematic review, we found that 70% of the included studies were industry-funded. We also noted that funding source was not disclosed for 19% of studies. We discussed that the choice of medication comparisons, dosages, and ...References1. Sismondo S. Pharmaceutical company funding and its consequences: a qualitative systematic review. Contemp Clin Trials. 2008;29:109-13. [PMID: 17919992] CrossrefMedlineGoogle Scholar2. Abou-Setta AM, Mousavi SS, Spooner C, Schouten JR, Pasichnyk D, Armijo-Olivo S, et al. First-Generation Versus Second-Generation Antipsychotics in Adults: Comparative Effectiveness. Rockville, MD: Agency for Healthcare Research and Quality; 2012. Accessed at http://effectivehealthcare.ahrq.gov/index.cfm/search-for-guides-reviews-and-reports/?pageaction=displayproduct&productid=1054 on 25 January 2013. Google Scholar Author, Article, and Disclosure InformationAuthors: Lisa Hartling, PhD; Amanda S. Newton, RN, PhD; Serdar Dursun, MD, PhDAffiliations: From University of Alberta, Edmonton, Alberta, Canada.Disclosures: Disclosures can be found at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M12-0362. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoAntipsychotics in Adults With Schizophrenia: Comparative Effectiveness of First-Generation Versus Second-Generation Medications Lisa Hartling , Ahmed M. Abou-Setta , Serdar Dursun , Shima S. Mousavi , Dion Pasichnyk , and Amanda S. Newton Antipsychotics in Adults With Schizophrenia: Does Sponsorship of Research Articles Affect the Findings? Thomas E. Finucane Metrics 5 March 2013Volume 158, Issue 5_Part_1 Page: 362 Keywords Antipsychotics Conflicts of interest Disclosure Forecasting Population statistics Schizophrenia Systematic reviews ePublished: 5 March 2013 Issue Published: 5 March 2013 Copyright & PermissionsCopyright © 2013 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...