Risk Factors for Low Bone Mass: Clinical Implications
Authors: Charles W. Slemenda
Journal: Annals of Internal Medicine (1993)

Editorials1 May 1993Risk Factors for Low Bone Mass: Clinical ImplicationsCharles W. Slemenda, MrPHCharles W. Slemenda, MrPHIndiana University School of Medicine, Indianapolis, IN 46202-5200.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-118-9-199305010-00014 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Cigarette smoking, alcohol consumption, exercise, and diet are among the risk factors examined in most studies of chronic disease. In this issue of Annals, these alterable behaviors and many other potential risk factors are examined as possible factors influencing the probability of having low bone mass. How can these data be used clinically? It has been presumed that certain risk factors can be used to identify patients with low bone mass and high risk for fracture. Although there are many factors significantly associated with bone mass in elderly women, the variability remains too great to accurately classify potential candidates for ...References1. Bauer DC, Browner W, Cauley JA, Orwoll ES, Scott JC, Black DM, et al. Factors associated with appendicular bone mass in older women. Ann Intern Med. 1993; 118:657-65. Google Scholar2. Cauley JA, Cummings SR, Seeley DG, Black D, Browner W, Kuller LH, et al. Effects of thiazide diuretic therapy on bone mass, fractures, and falls. Ann Intern Med. 1993; 118:667-74. Google Scholar3. Slemenda CW, Hui SL, Longcope C, Wellman H, Johnston CC. Predictors of bone mass in perimenopausal women: a prospective study of clinical data using photon absorptiometry. Ann Intern Med. 1990; 112:96-101. Google Scholar4. Stevenson JC, Lees B, Devenport M, Cust MP, Ganger KF. Determinants of bone density in normal women: risk factors for future osteoporosis? BMJ. 1989; 298:924-8. Google Scholar5. Sowers MR, Wallace RB, Lemke JH. Correlates of mid-radius bone density among postmenopausal women: a community study. Am J Clin Nutr. 1985; 41:1045-53. Google Scholar6. Hui SL, Slemenda CW, Johnston CC. Baseline measurement of bone mass predicts fracture in white women. Ann Intern Med. 1989; 111: 355-61. Google Scholar7. Cummings SR, Black DM, Nevitt MC, Browner WS, Cauley JA, Genant HK, et al. Appendicular bone mass and age predict hip fracture in women. JAMA. 1990; 263:665-8. Google Scholar8. Wasnich RD, Ross PD, Heilbrun LK, Vogel JM. Prediction of postmenopausal fracture risk with use of bone mineral measurements. Am J Obstet Gynecol. 1985; 153:745-51. Google Scholar9. Cummings SR, Black DM, Nevitt MC, Browner W, Cauley JC, Ensrud K, et al. Bone density at various sites for prediction of hip fractures. The Study of Osteoporotic Fractures Research Group. Lancet. 1993; 341:72-5. Google Scholar10. Clinical indications for bone mass measurements. A report from the Scientific Advisory Board of the National Osteoporosis Foundation. J Bone Miner Res. 1989; S2; 4:1-28. Google Scholar11. Lauritzen JB, Petersen MM, Lund B. Effect of external hip protectors on hip fractures. Lancet. 1993; 341:11-3. Google Scholar12. Johnston CC, Hui SL, Longcope C. Bone mass and sex steroid concentrations in postmenopausal Caucasian diabetics. Metabolism. 1985; 34:544-50. Google Scholar13. Barrett-Connor E, Holbrook TL. Sex differences in osteoporosis in older adults with non–insulin-dependent diabetes mellitus. JAMA. 1992; 268:3333-7. Google Scholar14. Hayes WC, Myers ER, Morris JN, Gerhart TN, Yett HS, Lipsitz LA. Impact near the hip dominates fracture risk in elderly nursing home residents who fall. Calcif Tissue Int. 1993; 52:192-8. Google Scholar15. Faulkner KG, Gluer CC, Palermo L, Black D, Genant HK, Cummings SR. Geometric measurements from dual x-ray absorptiometry scans predict hip fractures. J Bone Miner Res. 1992:7(S1):98. Google Scholar Author, Article, and Disclosure InformationAffiliations: Indiana University School of Medicine, Indianapolis, IN 46202-5200.Corresponding Author: Charles W. Slemenda, DrPH, Indiana University School of Medicine, Riley Research Wing, RR 135, 702 Barnhill Drive, Indianapolis, IN 46202-5200. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoFactors Associated with Appendicular Bone Mass in Older Women Douglas C. Bauer , Warren S. Browner , Jane A. Cauley , Eric S. Orwoll , Jean C. Scott , Dennis M. Black , Jo L. Tao , Steven R. Cummings , and Effects of Thiazide Diuretic Therapy on Bone Mass, Fractures, and Falls Jane A. Cauley , Steven R. Cummings , Dana G. Seeley , Dennis Black , Warren Browner , Lewis H. Kuller , Michael C. Nevitt , and Metrics Cited ByReferencesLow-Level Cadmium Exposure and OsteoporosisScreening for osteopenia and osteoporosis: Selection by body composition 1 May 1993Volume 118, Issue 9Page: 741-742KeywordsAlcoholsBoneBone resorptionEstrogensHip fracturesMedical risk factorsStandard deviationSurgeryType 2 diabetesWeight loss Issue Published: 1 May 1993 CopyrightCopyright © 1993 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...