Acute Exacerbations of Chronic Obstructive Pulmonary Disease
Authors: Michael S. Niederman, Sanjay Sethi, Fernando Martinez
Journal: Annals of Internal Medicine (2002)

Letters2 April 2002Acute Exacerbations of Chronic Obstructive Pulmonary DiseaseMichael S. Niederman, MD, Sanjay Sethi, MD, and Fernando Martinez, MDMichael S. Niederman, MDWinthrop University Hospital, Mineola, NY 11501State University of New York at Buffalo, Buffalo, NY 14215University of Michigan, Ann Arbor, MI 48109Search for more papers by this author, Sanjay Sethi, MDWinthrop University Hospital, Mineola, NY 11501State University of New York at Buffalo, Buffalo, NY 14215University of Michigan, Ann Arbor, MI 48109Search for more papers by this author, and Fernando Martinez, MDWinthrop University Hospital, Mineola, NY 11501State University of New York at Buffalo, Buffalo, NY 14215University of Michigan, Ann Arbor, MI 48109Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-136-7-200204020-00021 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:We read with interest the position paper reporting an evidence-based approach to the management of acute exacerbations of COPD [1]. However, we disagree with the approach and the conclusions reached about antibiotic therapy. The authors stated that the available data support the use of antibiotics over placebo for acute exacerbations of chronic bronchitis, particularly if those exacerbations are severe. However, they also concluded that older, commonly used antibiotics, which would be ineffective against increasingly resistant strains of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis, have not been proven to be any less effective than newer antibiotics and ...References1. Snow V, Lascher S, Mottur-Pilson C. Evidence base for management of acute exacerbations of chronic obstructive pulmonary disease. Ann Intern Med. 2001;134:595-9. [PMID: 11281744] LinkGoogle Scholar2. Murphy TF, Sethi S, Niederman MS. The role of bacteria in exacerbations of COPD. A constructive view. Chest. 2000;118:204-9. [PMID: 10893380] CrossrefMedlineGoogle Scholar3. Ball P, Harris JM, Lowson D, Tillotson G, Wilson R. Acute infective exacerbations of chronic bronchitis. QJM. 1995;88:61-8. [PMID: 7894990] MedlineGoogle Scholar4. Eller J, Ede A, Schaberg T, Niederman MS, Mauch H, Lode H. Infective exacerbations of chronic bronchitis: relation between bacteriologic etiology and lung function. Chest. 1998;113:1542-8. [PMID: 9631791] CrossrefMedlineGoogle Scholar5. Destache CJ, Dewan N, O'Donohue WJ, Campbell JC, Angelillo VA. Clinical and economic considerations in the treatment of acute exacerbations of chronic bronchitis. J Antimicrob Chemother. 1999;43 Suppl A 107-13. [PMID: 10225580] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Michael S. Niederman, MD; Sanjay Sethi, MD; Fernando Martinez, MDAffiliations: Winthrop University Hospital, Mineola, NY 11501State University of New York at Buffalo, Buffalo, NY 14215University of Michigan, Ann Arbor, MI 48109 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoEvidence Base for Management of Acute Exacerbations of Chronic Obstructive Pulmonary Disease Vincenza Snow , Steven Lascher , Christel Mottur-Pilson , and Acute Exacerbations of Chronic Obstructive Pulmonary Disease Vincenza Snow Acute Exacerbations of Chronic Obstructive Pulmonary Disease Claudia Stey Metrics Cited byChronic Obstructive Pulmonary Disease 2 April 2002Volume 136, Issue 7Page: 557KeywordsAntibioticsAntimicrobialsChronic bronchitisDrugsHospitalizationsLungsPneumoniaRandomized trialsStreptococcusVentilators ePublished: 2 April 2002 Issue Published: 2 April 2002 Copyright & PermissionsCopyright © 2002 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...