Creatinine Concentration of Human Fingernail and Toenail Clippings
Authors: JOHN I. LEVITT
Journal: Annals of Internal Medicine (1966)

Article1 February 1966Creatinine Concentration of Human Fingernail and Toenail ClippingsApplication in Determining the Duration of Renal FailureJOHN I. LEVITT, M.D.JOHN I. LEVITT, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-64-2-312 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe differentiation between acute and chronic renal failure in a patient who presents with uremia is often extremely difficult. With the advent of artificial dialysis this distinction has become of more than academic interest, since most centers are prepared to temporarily dialyze the patient with acute renal failure in the hope of eventual recovery, whereas they are not prepared to do chronic dialysis on those patients with end-stage renal disease.It was postulated that the concentration of creatinine in fingernail and toenail clippings might be of value in separating acute from chronic uremia. If nail creatinine concentration were a reflection...References1. VAN PILSUMMARTINKITOHESS JFRPEJ: Determination of creatine, creatinine, arginine, guanidinoacetic acid, guanidine, and methyl guanidine in biological fluids. J. Biol. Chem. 222: 225, 1956. CrossrefMedlineGoogle Scholar2. PETERS JH: The determination of creatinine and creatine in blood and urine with the photoelectric colorimeter. J. Biol. Chem. 146: 179, 1942. CrossrefGoogle Scholar3. 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To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Minneapolis, MinnesotaFrom the Department of Medicine, University of Minnesota Medical School, Minneapolis, Minn.This study was supported by grants 63-G-172 and 64-G-11 from the American Heart Association, Inc., New York, N. Y., and by grant HE08775 from the National Institutes of Health, Bethesda, Md.Requests for reprints should be addressed to John I. Levitt, M.D., Box 240, >Department of Medicine, University of Minnesota Hospitals, Minneapolis, Minn. 55455. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByNails in Systemic DiseaseA novel technique to measure chronic levels of corticosterone in turtles living around a major roadwayThe Nail in Systemic DiseaseNail calcium and magnesium content in relation to age and bone mineral densityNails (of the Fingers and Toes)Nails in Systemic DiseaseCan fingernail creatinine concentrations be used to predict duration of azotemia?Fingernail Creatinine as a Predictor of Prior Renal FunctionNails in Systemic DiseaseAnatomy and Physiology 1 February 1966Volume 64, Issue 2Page: 312-327KeywordsAcute renal failureAttentionCreatinineHeart failureHomotransplantationLongitudinal studiesMedical dialysisRenal failure Issue Published: 1 February 1966 PDF DownloadLoading ...