Gonococcal Meningitis Complicating Treated Gonococcal Urethritis
Authors: WILLIAM T. LAMPE
Journal: Annals of Internal Medicine (1963)

Case Studies1 July 1963Gonococcal Meningitis Complicating Treated Gonococcal UrethritisWILLIAM T. LAMPE II, M.D.WILLIAM T. LAMPE II, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-59-1-94 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptGonococcal meningitis is a rare disease, only 26 proved cases having been reported in the world literature (1). Most of these occurred before the advent of antibiotics. This report deals with the first known case of meningitis appearing in an acute treated gonococcal urethritis that was otherwise uncomplicated. Two points are of interest: First, an accurately diagnosed gonococcal urethritis failed to respond to penicillin in doses usually considered to be "adequate," despite the demonstration of the organism's sensitivity to penicillinin vitro. Second, septicemia and meningitis occurred with the same organism that did respond to treatment with penicillin in larger...References1. IKEJIANI O: Gonococcal meningitis: a review of literature and report of a case. West Afr. Med. J. 7: 139, 1958. MedlineGoogle Scholar2. : Resistance of gonorrhea to penicillin. Lancet 2: 246, 1961. Google Scholar3. MCCARTHYWALLMARKFINLAND CGGM: In vitro activity of various penicillins. Amer. J. Med. Sci. 241: 49, 1961. CrossrefGoogle Scholar4. Penicillins in treatment of gonorrhea. Brit. Med. J. 1: 311, 1962. Google Scholar5. EPSTEIN E: Failure of penicillin in the treatmen of acute gonorrhea in American troops in Korea. JAMA 169: 1055, 1959. CrossrefMedlineGoogle Scholar6. GANGAROSACARLY EJGC: Validity of reports of penicillin resistance and gonorrhea. JAMA 173: 1808, 1960. CrossrefMedlineGoogle Scholar7. INONEUGEBAUERLUCAS JDLRN: Isolation of Mima polymorpha var. oxidans from two patients with urethritis and a clinical syndrome resembling gonorrhea. Amer. J. Clin. Path. 32: 364, 1959. CrossrefMedlineGoogle Scholar8. STIGLERMCLESTER SLJS: Gonococcic meningitis fifteen years after urethritis. JAMA 136: 919, 1948. CrossrefMedlineGoogle Scholar9. Notes on management of veneral disease. Public Health Service Publication No. 859, 22 pp., 1961. The Department of Health, Education and Welfare, United States Public Health Service, Communicable Disease Center, Atlanta 22, Georgia. Google Scholar10. SABATHKIVLAHAN LDJJ: Dosage of penicillin for acute gonorrhea of males. Amer. J. Med. Sci. 242: 663, 1961. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: WILLIAM T. LAMPEII, M.D.Affiliations: York, PennsylvaniaFrom the Department of Internal Medicine, York Hospital, York, Pennsylvania.Requests for reprints should be addressed to William T. Lampe, II, M.D., 436 West Market Street, York, Pennsylvania. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byGonococcal Meningitis Diagnosed by DNA Amplification: Case Report and Review of the LiteratureGonococcal MeningitisDisseminated Gonococcal InfectionKING K. HOLMES, M.D., Ph.D., GEORGE W. COUNTS, M.D., HARRY N. BEATY, M.D., F.A.C.P.Bacterial Meningitis — A Review of Selected Aspects 1 July 1963Volume 59, Issue 1_Part_1Page: 94-96KeywordsAntibioticsHospital medicineMeningitisNeisseria gonorrhoeaePenicillinSepsis ePublished: 1 December 2008 Issue Published: 1 July 1963 PDF downloadLoading ...