Hepatitis Hyperimmune Globulin and Exposure to Human Immunodeficiency Virus
Authors: ROBERT P. NELSON
Journal: Annals of Internal Medicine (1986)

Letters and Corrections1 September 1986Hepatitis Hyperimmune Globulin and Exposure to Human Immunodeficiency VirusROBERT P. NELSON JR., M.D., DENNIS K. LEDFORD, M.D., PHILLIP W. DEVOE, M.D., RICHARD F. LOCKEY, M.D.ROBERT P. NELSON JR., M.D.Search for more papers by this author, DENNIS K. LEDFORD, M.D.Search for more papers by this author, PHILLIP W. DEVOE, M.D.Search for more papers by this author, RICHARD F. LOCKEY, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-105-3-465_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Although the relative risk of transmission of infection with human immunodeficiency virus (HIV, formerly HTLV-III/LAV) from high-risk patients to health care workers is low, there has been at least one documented HIV seroconversion after needlestick injury (1) and two exposures that probably resulted in transient symptoms and seroconversion (2). A health care worker at our institution was exposed through a needlestick accident to blood from a hemophiliac with the acquired immunodeficiency syndrome (AIDS)-related complex. She was given hepatitis B hyperimmune globulin (HyperHep; Cutter Biological, Berkeley, California), 0.06 µ-L/kg body weight intramuscularly, within 4 hours of the accident....References1. Needlestick transmission of HTLV-III from a patient infected in Africa. Lancet. 1984;2:1376-7. MedlineGoogle Scholar2. . Update: prospective evaluation of health-care workers exposed via the parenteral or mucous-membrane route to blood or body fluids from patients with acquired immunodeficiency syndrome—United States. MMWR. 1985;34:101-3. MedlineGoogle Scholar3. DE NONONHA F, ESSES M, and BOLOGNESI D. Influence of antisera to oncornovirus glycoprotein (gp71) on infection of cats with feline leukemia virus. Virology. 1978;85:617-21. CrossrefMedlineGoogle Scholar4. ROBERT-GUROFF M, BROWN M, and GALLO R. HTLV-III neutralizing antibodies in patients with AIDS and AIDS-related complex. Nature. 1985; 316:72-4. CrossrefMedlineGoogle Scholar5. ALTER H, FAUCI A, and GALLO R. Transmission of HTLV-III infection from human plasma to chimpanzees: an animal model for the acquired immunodeficiency syndrome. Science. 1984;226:549-52. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: ROBERT P. NELSONJR., M.D.; DENNIS K. LEDFORD, M.D.; PHILLIP W. DEVOE, M.D.; RICHARD F. LOCKEY, M.D.Affiliations: University of South Florida College of Medicine James A. Haley Veterans Administration Hospital Tampa, FL 33612 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byFamilial hemophagocytic lymphohistiocytosis associated with disseminated T-cell lymphoma: A report of two siblingsImpaired Urinary Excretion of Soluble IL-2 Receptors in Patients with Systemic Lupus Erythematosus and Rheumatoid ArthritisSerum Levels of Soluble Interleukin-2 Receptor in Pulmonary TuberculosisSoluble interleukin 2 receptor molecules in the serum of patients with autoimmune diseases 1 September 1986Volume 105, Issue 3Page: 465-465KeywordsAIDSBloodBody weightGlobulinsHealth care providersHepatitis BHepatitis virusesHIVInfectious hepatitisRelative risk ePublished: 1 December 2008 Issue Published: 1 September 1986 PDF downloadLoading ...