Somatostatin Receptor Scintigraphy in the Zollinger-Ellison Syndrome
Authors: Fathia Gibril
Journal: Annals of Internal Medicine (1997)

Letters1 May 1997Somatostatin Receptor Scintigraphy in the Zollinger-Ellison SyndromeFathia Gibril, MD and Robert T. Jensen, MDFathia Gibril, MDNational Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD 20892Search for more papers by this author and Robert T. Jensen, MDNational Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD 20892Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-126-9-199705010-00022 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:Drs. Ciaccia and Gress raise several points; we agree with some and disagree with others. First, our initial studies with SRS were done to determine the overall role of various imaging studies in the management of patients with gastrinomas. Endoscopic ultrasonography is primarily used in patients before surgery and has either a minimal role or no role in the 40% to 50% of patients who do not undergo surgery or have liver metastases [1]. Conventional studies and SRS have a potential role in assessing all aspects of disease (preoperative assessment, extent of metastases, response to chemotherapy). Therefore, we ...References1. Jensen RT, Gardner JD. Gastrinoma. In: Go VL, DiMagno EP, Gardner JD, Lebenthal E, Reber HA, Scheele GA, eds. The Pancreas: Biology, Pathobiology and Disease. 2d ed. New York: Raven; 1993:931-78. Google Scholar2. Gibril F, Reynolds JC, Doppman JL, Chen CC, Venzon DJ, Termanini B, et al. Somatostatin receptor scintigraphy: its sensitivity compared with that of other imaging methods in detecting primary and metastatic gastrinomas. A prospective study. Ann Intern Med. 1996; 125:26-34. Google Scholar3. Termanini B, Gibril F, Reynolds JC, Chen CC, Doppman JL, Stewart CA, et al. Value of somatostatin receptor scinitgraphy: a prospective study in Zollinger-Ellison syndrome of its effect on clinical management. Gastroenterology. 1996:[In press]. Google Scholar4. Ruszniewski P, Amouyal P, Amouyal G, Grange JD, Mignon M, Bouch O, et al. Localization of gastrinomas by endoscopic ultrasonography in patients with Zollinger-Ellison syndrome. Surgery. 1995; 117:629-35. Google Scholar5. de Kerviler E, Cadiot G, Lebtahi R, Faraggi M, le Guludec D, Mignon M. Somatostatin receptor scintigraphy in forty-eight patients with the Zollinger-Ellison syndrome. Eur J Nucl Med. 1994; 21:1191-7. Google Scholar Author, Article, and Disclosure InformationAuthors: Fathia Gibril, MD; Robert T. Jensen, MDAffiliations: National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD 20892 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 May 1997Volume 126, Issue 9Page: 741-742KeywordsEndoscopic surgeryInsulinomaLiverProspective studiesRadionuclide imagingResearch laboratoriesSomatostatinSurgeryUltrasound imagingZollinger Ellison syndrome ePublished: 15 August 2000 Issue Published: 1 May 1997 Copyright & PermissionsCopyright © 1997 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...