Plasmodium falciparum Malaria and Intravenous Quinidine Gluconate
Authors: JAN M. AGOSTI
Journal: Annals of Internal Medicine (1985)

Letters and Corrections1 August 1985Plasmodium falciparum Malaria and Intravenous Quinidine GluconateJAN M. AGOSTI, M.D., KIRK D. MILLER, M.D., MARGUERITE PAPPAIOANOU, D.V.M., Ph.D., ELAINE C. JONG, M.D.JAN M. AGOSTI, M.D.Search for more papers by this author, KIRK D. MILLER, M.D.Search for more papers by this author, MARGUERITE PAPPAIOANOU, D.V.M., Ph.D.Search for more papers by this author, ELAINE C. JONG, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-103-2-307_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Because of its rapid activity, quinine dihydrochloride is the drug of choice for the intitial treatment of severePlasmodium falciparuminfections. In the United States this drug must be obtained from the Centers for Disease Control, resulting in delays of up to 12 hours in starting therapy. Prompt therapy ofP. falciparuminfections is essential in reducing the risk of death. Indeed, a study of cerebral malaria in Thailand has shown that patients who died received quinine later in their illness than those who survived (1). We report the case of a patient with cerebral malaria treated...References1. WARRELL D, LOOAREESUWAN S, and WARRELL M. Dexamethasone proves deleterious in cerebral malaria. N Engl J Med. 1982;306:313- 9. CrossrefMedlineGoogle Scholar2. SANDERS J and DAWSON W. Efficacy of quinidine in malaria. JAMA. 1932;99:1773-7. CrossrefGoogle Scholar3. PHILLIPS R, LOOAREESUWAN S, WARRELL D, KARBWANG J, and WHITE N. Parenteral quinidine gluconate proves effective in severe falciparum malaria [Abstract]. Calgary, Canada: Eleventh International Congress on Tropical Medicine and Malaria. 1984;118. Google Scholar4. WHITE N, LOOAREESUWAN S, and WARRELL D. Quinine and quinidine: a comparison of EKG effects during the treatment of malaria. J Cardiovasc Pharmacol. 1983;5:173-5. CrossrefMedlineGoogle Scholar5. SWERDLOW C, YU J, and JACOBSON E. Safety and efficacy of intravenous quinidine. Am J Med. 1983;75:36-42. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: JAN M. AGOSTI, M.D.; KIRK D. MILLER, M.D.; MARGUERITE PAPPAIOANOU, D.V.M., Ph.D.; ELAINE C. JONG, M.D.Affiliations: University of Washington Seattle, WA 98195 Center for Infectious Diseases Centers for Disease Control Atlanta, GA 30333 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byContinuous intravenous quinidine infusion for the treatment of atrial fibrillation or flutter: A case seriesTreatment of Severe Malaria in the United States with a Continuous Infusion of Quinidine Gluconate and Exchange TransfusionREDUCED IN-VITRO SUSCEPTIBILITY TO MEFLOQUINE IN WEST AFRICAN ISOLATES OF PLASMODIUM FALCIPARUMThe treatment of severe falciparum malariaThe treatment of severe falciparum malaria 1 August 1985Volume 103, Issue 2Page: 307-307KeywordsCerebral malariaDrug regulationDrug therapyDrugsMalariaPlasmodium falciparumQuinine ePublished: 1 December 2008 Issue Published: 1 August 1985 PDF downloadLoading ...