Cimetidine and Arrhythmia Suppression
Authors: MOSHE LIGUMSKY
Journal: Annals of Internal Medicine (1978)

Letters and Corrections1 December 1978Cimetidine and Arrhythmia SuppressionMOSHE LIGUMSKY, M.D., MARA SHOCHINA, M.D., DANIEL RACHMILEWITZ, M.D.MOSHE LIGUMSKY, M.D.Search for more papers by this author, MARA SHOCHINA, M.D.Search for more papers by this author, DANIEL RACHMILEWITZ, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-89-6-1008 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Since the publication of the editorial on cimetidine in this journal (1), it has been reported to cause several side effects such as impairment of renal and liver functions (2), mental confusion, and elevation of plasma prolactin. In the case reported here, cimetidine controlled arrhythmia while slowing the heart rate.A 72-year-old man was admitted to the department of surgery for a feeding gastrostomy. The patient suffered a cerebral vascular accident 5 years previously and has had left hemiplegia since then. Two months before the present admission, his neurologic status deteriorated after evacuation of chronic subdural hematoma....References1. HIRSCHOWITZ B: Histamine H-2 receptor antagonists (editorial). Ann Intern Med 87:373-375, 1977 LinkGoogle Scholar2. Third symposium on histamine H2 receptor antagonists: clinical results with cimetidine. Gastroenterology 74:339-488, 1978 CrossrefMedlineGoogle Scholar3. REDINGDEVROEDEBARBIER PCP: Bradycardia after cimetidine (letter). Lancet 2:1227, 1977 CrossrefMedlineGoogle Scholar4. OWEN D: Histamine receptors in the cardiovascular system. Gen Pharmacol 8:141-156, 1977 CrossrefMedlineGoogle Scholar5. ZAVECZLEVI JR: Pharmacological characterization of the receptors mediating histamine-induced idioventricular tachyarrhythmia. Fed Proc 35:645, 1976 Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Hadassah University Hospital Jerusalem, Israel PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byNegative chronotropic effects of nizatidine.H2-receptor antagonism is not pro-arrhythmic in a chronic canine modelHistaminwirkungen am Herzen unter besonderer Berücksichtigung kardialer Nebenwirkungen von H2-Rezeptor-AntagonistenCardiovascular Effects of H 2 -receptor AntagonistsProphylaxis for pulmonary acid aspirationSafety perspectives on parenteral H2-receptor antagonistsUsefulness and safety of cimetidine in patients receiving mexiletine for ventricular arrhythmiaSinus Node Function and DysfunctionCimetidine induced arrhythmiasDrugs Five Years Later Cimetidine II. Adverse Reactions and Patterns of UseJAMES W. FRESTON, M.D., Ph.D.Cimetidine, vasopressin and chronotropic incompetenceSIDE-EFFECTS OF RANITIDINECIMETIDINE, RANITIDINE, AND HEART RATEEffects of histamine type 2 receptor stimulation on myocardial function in normal subjects.The Pathophysiological Role of Histamine and Potential Therapeutic Uses of H1 and H2 AntihistaminesContrôle de l’acidité gastrique par la cimétidine donnée en prémédication avant l’anesthésie générale: efficacité et tolérancePharmacokinetics of the H2- receptor antagonist ranitidine in man.Cimetidine and Sinus BradycardiaThe effects of chronic oral cimetidine therapy on the cardiovascular system in man.Inhibition of Histamine-Stimulated Increases in Neart Rate in Man with the H 2 -Histamine Receptor Antagonist CimetidineEffect of fifteen months of double-blind treatment with cimetidine and placebo on peptic ulcer recurrenceElectrophysiologic Properties of Cimetidine in ManCardiac Arrest after Intravenous Injection of CimetidineCimetidine and Sinus-Node FunctionHistamine 2 Receptor Antagonism by Cimetidine and Sinus-Node Function 1 December 1978Volume 89, Issue 6Page: 1008-1009KeywordsArrhythmiaBlood plasmaGastroenterology and hepatologyHeart rateLiverProlactinSurgery Issue Published: 1 December 1978 PDF downloadLoading ...