Fever from Ibuprofen in a Patient with Lupus Erythematosus
Authors: BARBARA MANDELL
Journal: Annals of Internal Medicine (1976)

Letters1 August 1976Fever from Ibuprofen in a Patient with Lupus ErythematosusBARBARA MANDELL, M.D., HARRY S. SHEN, M.D., BONNIE HEPBURN, M.D., F.A.C.P.BARBARA MANDELL, M.D.Search for more papers by this author, HARRY S. SHEN, M.D.Search for more papers by this author, BONNIE HEPBURN, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-85-2-209 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptDrug sensitivity reactions are frequently observed in patients with systemic lupus erythematosus (1). We wish to report a case history describing a febrile reaction associated with the administration of ibuprofen (Motrin®) to a patient with systemic lupus erythematosus. Ibuprofen is a nonsteroidal, anti-inflammatory agent with analgesic and antipyretic effects. It has recently been made available in the United States for treatment of rheumatoid arthritis and degenerative joint disease. It has also been used in the treatment of systemic lupus erythematosus (2). We are not aware of previously published reports describing febrile reactions to this drug.A 36-year-old black woman was...References1. DUBOIS E: The clinical picture of systemic lupus erythematosus, in Lupus Erythematosus, edited by DUBOIS EL. Los Angeles, University of Southern California Press, 1974, pp. 249-253 Google Scholar2. DUBOIS E: Ibuprofen for systemic lupus erythematosus (letter). N Engl J Med 293:779, 1975 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Department of Medicine CMDNJ—Rutgers Medical School Raritan Valley Hospital Green Brook, NJ 08812 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited BySystematic review: ibuprofen-induced liver injuryDrug FeverA Case of Anaphylactic Reaction to Ibuprofen in a Child with Still’s DiseaseDécouverte d'un lupus érythémateux disséminé à l'occasion d'une hépatite à l'ibuprofèneDrug- and Chemical-Induced Aseptic Meningitis: A Review of the LiteratureRecurrent ibuprofen-induced aseptic meningitis: third episode after only 200 mg of generic ibuprofenTreatmentSouthwestern Internal Medicine Conference: Drug Fever: Mechanisms, Maxims and MisconceptionsDrug Fever: A Critical Appraisal of Conventional Concepts An Analysis of 51 Episodes in Two Dallas Hospitals and 97 Episodes Reported in the English LiteraturePHILIP A. MACKOWIAK, M.D., CHARLES F. LeMAISTRE, M.D.Severe systemic hypersensitivity reaction to ibuprofen occurring after prolonged therapyIbuprofen-induced Meningitis in a Male with Systemic Lupus ErythematosusRare adverse reactions to non-steroidal anti-inflammatory drugsDrug-Induced FeverAdverse reactions to nonsteroidal anti-inflammatory drugs diclofenac compared with other nonsteroidal anti-inflammatory drugsUse of Ibuprofen in Unusual CircumstancesAnalgesics and Nonsteroidal Anti-Inflammatory DrugsChanges in body temperature after administration of antipyretics, LSD, Δ9-THC, CNS depressants and stimulants, hormones, inorganic ions, gases, 2,4-DNP and miscellaneous agentsAntiglobulin-Tests for Detection of Auto-Immunohaemolytic Anaemia During Long-Term Treatment with IbuprofenComparative effects of aspirin and ibuprofen in the management of systemic lupus erythematosusAnalgesics, allergy and asthma.IbuprofenTHOMAS G. KANTOR, M.D.Anti-inflammatory analgesics and drugs used in rheumatism and gout 1 August 1976Volume 85, Issue 2Page: 209-210KeywordsAnalgesicsDegenerative joint diseaseDrugsFeversIbuprofenLupus erythematosusNSAIDsRheumatoid arthritis Issue Published: 1 August 1976 PDF DownloadLoading ...