Testing for Human Immunodeficiency Virus
Authors: JAMES J. GOEDERT
Journal: Annals of Internal Medicine (1986)

Editorials1 October 1986Testing for Human Immunodeficiency VirusJAMES J. GOEDERT, M.D.JAMES J. GOEDERT, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-105-4-609 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptMore than a million Americans are infected with the human immunodeficiency virus (HIV, formerly HTLV-III/LAV), and their risk for the acquired immunodeficiency syndrome (AIDS) may exceed 30% (1, 2). Physicians in clinical practice must be prepared soon to counsel and care for persons identified as infected through the large HIV screening programs of the American blood and plasma collection agencies and armed forces (3, 4). Physicians also will need to use and interpret HIV assays as these tests become part of standard medical practice in the care of drug users, hemophiliacs, and homosexually or heterosexually active adults, as well as...References1. Coolfont report: a Public Health Service plan for prevention and control of AIDS and the AIDS virus. Public Health Rep. 1986;101:341-8. MedlineGoogle Scholar2. GOEDERTBIGGARWEISS JRS. Three-year incidence of AIDS in five cohorts of HTLV-III-infected risk group members. Science. 1986;231:992-5. CrossrefMedlineGoogle Scholar3. National Institutes of Health Consensus Development Conference Statement on The Impact of Routine HTLV-III Antibody Testing of Blood and Plasma Donors on Public Health, July 7-9, 1986. Bethesda: National Institutes of Health; 1986. Google Scholar4. . Human T-lymphotropic virus type III/lymphadenopathy-associated virus antibody prevalence in U.S. military recruit applicants. MMWR. 1986;35:421-4. MedlineGoogle Scholar5. WARDGRINDONFEORINOSCHABLEPARVINALLEN JAPCMJ. Laboratory and epidemiologic evaluation of an enzyme immunoassay for antibodies to HTLV-III. JAMA. 1986;256:357-61. CrossrefMedlineGoogle Scholar6. WEISSGOEDERTSARNGADHARAN SJM. Screening test for HTLV-III (AIDS agent) antibodies: specificity, sensitivity, and applications. JAMA. 1985;253:221-5. CrossrefMedlineGoogle Scholar7. SIVAKWORMSER SG. Predictive value of a screening test for antibodies to HTLV-III. Am J Clin Pathol. 1986;85:700-3. CrossrefMedlineGoogle Scholar8. ANDERSONGORGONEMARLINK KBR. Transfusion-acquired human immunodeficiency virus infection among immunocom-promised persons. Ann Intern Med. 1986;105:519-27 LinkGoogle Scholar9. BURKEREDFIELD DR. False-positive Western blot tests for antibodies to HTLV-III [Letter]. JAMA. 1986;253:347. CrossrefGoogle Scholar10. SALAHUDDINMARKHAMPOPOVIC SPM. Isolation of infectious human T-cell leukemia/lymphotropic virus type HI (HTLV-III) from patients with acquired immunodeficiency syndrome (AIDS) or AIDS-related complex (ARC) and from healthy carriers: a study of risk groups and tissue sources. Proc Natl Acad Sci USA. 1985;82:5530-4. CrossrefMedlineGoogle Scholar11. SCHULTZASCHAUERHENGSTER TJP. Envelope gene-derived recombinant peptide in the serodiagnosis of human immunodeficiency virus infection. Lancet. 1986;2:111-2. CrossrefMedlineGoogle Scholar12. GOUDSMITDE WOLFPAUL JFD. Expression of human immunodeficiency virus antigen (HIV-Ag) in serum and cerebral spinal fluid during acute and chronic infection. Lancet. 1986;2:177-80. CrossrefMedlineGoogle Scholar13. GOEDERTBIGGARMELBYE JRM. Effect of T4 count and cofactors on AIDS incidence in homosexual men infected with human immunodeficiency virus. JAMA. (In press). Google Scholar14. ROBERT-GUROFFBROWNGALLO MMR. HTLV-III-neutralizing antibodies in patients with AIDS and AIDS-related complex. Nature. 1985;316:72-4. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: National Cancer Institute Bethesda, Maryland Nextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byRetroviruses—Human Immunodeficiency VirusUtility of quantitative enzyme immunoassay reactivity for predicting human immunodeficiency virus seropositivity in low- and high-prevalence populationsReview of Testing for Human Immunodeficiency VirusLaboratory Evaluations of Infections in Immunosuppressed Transplant PatientsEtiology, Pathogenesis, and DiagnosisIndirect immunofluorescence test performance and questionnaire results from the Centers for Disease Control Model Performance Evaluation Program for human immunodeficiency virus type 1 testingHuman Immunodeficiency Virus (HIV) Infection and the KidneyRichard J. Glassock, MD, Arthur H. Cohen, MD, Gabriel Danovitch, MD, K. Peter Parsa, MDCurrent status of clinical laboratory tests for the human immunodeficiency virusScreening strategies to inhibit the spread of AIDSEvaluation of human immunodeficiency virus seroprevalence in population surveys using pooled seraThe Acquired Immunodeficiency SyndromeHuman immunodeficiency virus infection in childrenThe Acquired Immunodeficiency Syndrome Is a Primary Care DiseaseDonald W. Northfelt, MD, Rodney A. Hayward, MD, Martin F. Shapiro, MD, PhDMeasurement of the False Positive Rate in a Screening Program for Human Immunodeficiency Virus InfectionsAdequacy of the ELISA Test for Screening Corneal Transplant DonorsAIDS Testing and Informed ConsentSerologic Testing for Human Immunodeficiency Virus AntibodiesAIDS — wo stehen wir heute?Comparison of Western blot (immunoblot) based on recombinant-derived p41 with conventional tests for serodiagnosis of human immunodeficiency virus infectionsAIDS and Advocate ScienceWhat is Safe Sex?The Coexistence of Acquired Immune Deficiency Syndrome and Chronic DiseaseTesting for Human Immunodeficiency VirusJOSEPH A. STANKAITIS, M.D., M.P.H., JOHN P. BIGOS, M.D., M.P.H. 1 October 1986Volume 105, Issue 4Page: 309-610KeywordsAIDSAddictsArmed forcesBlood plasmaHIV ePublished: 1 December 2008 Issue Published: 1 October 1986 PDF downloadLoading ...