A Practical Approach to the Use of Rubella Vaccine
Authors: JOSEPH STOKES
Journal: Annals of Internal Medicine (1971)

Editorials1 January 1971A Practical Approach to the Use of Rubella VaccineJOSEPH STOKES JR., M.D.JOSEPH STOKES JR., M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-74-1-136 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe approprute use of the attenuated rubella vaccine, as recommended by the Public Health Service Advisory Committee on Immunization and by a similar committee of the American Academy of Pediatrics, is in the age range from 1 to 12 years because natural rubella among susceptibles in this age group poses the greatest threat to pregnant mothers, and it is in this age period that the reservoir of susceptibles can be most readily wiped out.Numerous field studies (1-6) have shown that attenuated rubella virus vaccine in a single dose will protect against the natural disease. It has also been demonstrated...References1. HILLEMANBUYNAKWEIBEL MER: Live attenuated rubella virus vaccine. New Eng J Med 279:300-303, 1968 CrossrefMedlineGoogle Scholar2. WEIBELSTOKESBUYNAK RJE: Live attenuated rubella virus vaccines prepared in duck embryo cell culture. II. Clinical tests in families and in an institution. JAMA 205:554-558, 1968 CrossrefMedlineGoogle Scholar3. MEYERPARKMANPANOS HPT: Attenuated rubella virus. II. Production of experimental live-virus vaccine and clinical trial. New Eng J Med 275:575-580, 1966 CrossrefMedlineGoogle Scholar4. MCCOLLUMRANDOLFBYRNE RME: Rubella virus vaccine (HPV-77-DE-5) antigenic and protective efficacy in a community trial. Amer J Dis Child 118:186-189, 1969 CrossrefMedlineGoogle Scholar5. MEYERPARKMANHOBBINS HPT: Clinical studies with experimental live rubella virus vaccine (strain HPV 77). Evaluation of vaccine-induced immunity. Amer J Dis Child 115:648-654, 1968 CrossrefMedlineGoogle Scholar6. GRAYSTONDETELSCHEN JRK: Field trial of live attenuated rubella virus vaccine during an epidemic, on Taiwan. Preliminary report of efficacy of three HPV-77 strain vaccines in the prevention of clinical rubella. JAMA 207: 1107-1110, 1969 CrossrefMedlineGoogle Scholar7. WEIBELBUYNAKSTOKES REJ: Persistence of immunity four years following Jeryl Lynn Strain live mumps virus vaccine. Pediatrics 45:821-826, 1970 MedlineGoogle Scholar8. SCOTTBYRNE HE: Exposure of susceptible pregnant women to rubella vaccines: serologic findings during the Rhode Island immunization campaign. JAMA In press, 1971 CrossrefGoogle Scholar9. LEHANENEWBERGBEAM DNW: Evaluation of rubella herd immunity during an epidemic. JAMA 213: 2236-2239, 1970 CrossrefMedlineGoogle Scholar10. LERMANNANKERVISHEGGIE SGA: Immunologic response, virus excretion, and joint reactions with rubella vaccine. A study of adolescent girls and young women given live attenuated virus vaccine (HPV-77:DE-5). Ann Intern Med 74:67-73, 1971 LinkGoogle Scholar11. WEIBELSTOKESBUYNAK RJE: Rubella vaccination in adult females. New Eng J Med 280:682-685, 1969 CrossrefMedlineGoogle Scholar12. HORSTMANNPAJOTLIEBHABER DTH: Epidemiology of rubella. Subclinical infection and occurrence of reinfection. Amer J Dis Child 118:133-136, 1969 CrossrefMedlineGoogle Scholar13. DAVISLARSONSIMSARIAN WHJ: A study of rubella immunity and resistance to reinfection. JAMA In press, 1970 Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: The Henry Phipps Institute University of Pennsylvania Philadelphia, Pa. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByInfectious diseases: annual review of significant publications. 1 January 1971Volume 74, Issue 1Page: 136-137KeywordsAge groupsMedical servicesPediatricsPregnancyRubellaRubella vaccineVaccines Issue Published: 1 January 1971 PDF DownloadLoading ...