The Adult Childhood Cancer Survivor and the General Internist: Suggestions for Patient and Provider Education
Authors: Dava Szalda, Jill P. Ginsberg
Journal: Annals of Internal Medicine (2014)

Editorials7 January 2014The Adult Childhood Cancer Survivor and the General Internist: Suggestions for Patient and Provider EducationDava Szalda, MD and Jill P. Ginsberg, MDDava Szalda, MDFrom The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.Search for more papers by this author and Jill P. Ginsberg, MDFrom The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/M13-2718 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Childhood cancer survivors (CCSs) are entering the adult health care system in increasing numbers. Cure rates in pediatric oncology now reach 80%, and approximately 1 in 700 young adults is a CCS (1). Longitudinal follow-up of large cohorts of CCSs into adulthood has shown that they are 3.3 times more likely than age-matched control participants to have chronic health conditions (2). These conditions include end-organ damage, such as cardiac, pulmonary, and thyroid dysfunction secondary to cytotoxic treatments, during childhood. Childhood cancer survivors are also at risk for secondary cancer, such as thyroid, breast, and colon cancer, depending on previous exposures ...References1. Hewitt M, Weiner SL, Simone JV. Childhood Cancer Survivorship: Improving Care and Quality of Life. Washington, DC: National Academies Pr; 2003. Google Scholar2. Oeffinger KC, Mertens AC, Sklar CA, Kawashima T, Hudson MM, Meadows AT, et al; Childhood Cancer Survivor Study. Chronic health conditions in adult survivors of childhood cancer. N Engl J Med. 2006;355:1572-82. [PMID: 17035650] CrossrefMedlineGoogle Scholar3. Hewitt M, Greenfield S, Stovall E. From Cancer Patient to Cancer Survivor: Lost in Transition. Washington, DC: National Academies Pr; 2006. Google Scholar4. Eshelman-Kent D, Kinahan KE, Hobbie W, Landier W, Teal S, Friedman D, et al. Cancer survivorship practices, services, and delivery: a report from the Children's Oncology Group (COG) nursing discipline, adolescent/young adult, and late effects committees. J Cancer Surviv. 2011;5:345-57. [PMID: 21894490] CrossrefMedlineGoogle Scholar5. Nathan PC, Hayes-Lattin B, Sisler JJ, Hudson MM. Critical issues in transition and survivorship for adolescents and young adults with cancers. Cancer. 2011;117:2335-41. [PMID: 21523755] CrossrefMedlineGoogle Scholar6. Suh E, Daugherty CK, Wroblewski K, Lee H, Kigin ML, Rasinski KA, et al. General internists' preferences and knowledge about the care of adult survivors of childhood cancer. A cross-sectional survey. Ann Intern Med. 2014;160:11-7. LinkGoogle Scholar7. Children's Oncology Group. Long-term follow-up guidelines for survivors of childhood, adolescent, and young adult cancer. Version 3.0. Arcadia, CA: Children's Oncology Group; 2008. Accessed at www.survivorshipguidelines.org/pdf/ltfuguidelines.pdf on 20 November 2013. Google Scholar8. Nekhlyudov L, Aziz NM, Lerro C, Virgo KS. Oncologists' and primary care physicians' awareness of late and long-term effects of chemotherapy: implications for care of the growing population of survivors. J Oncol Pract. 2013;:. [PMID: 24222054] MedlineGoogle Scholar9. Nekhlyudov L, Greenfield S. Cancer survivorship care for the general internist: have we paved the way for a smoother transition? J Gen Intern Med. 2009;24 Suppl 2 S381-2. [PMID: 19838835] CrossrefMedlineGoogle Scholar10. Schwartz LA, Brumley LD, Tuchman LK, Barakat LP, Hobbie WL, Ginsberg JP, et al. Stakeholder validation of a model of readiness for transition to adult care. JAMA Pediatr. 2013;167:939-46. [PMID: 23959392] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.Disclosures: None disclosed. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M13-2718.Corresponding Author: Jill P. Ginsberg, MD, The Children's Hospital of Philadelphia, Division of Oncology, Colket Translational Research Building, 3501 Civic Center Boulevard, Room 10307, Philadelphia, PA 19104; e-mail, [email protected]chop.edu.Current Author Addresses: Dr. Szalda: The Children's Hospital of Philadelphia, Wood 4 Oncology, 34th and Civic Center Boulevard, Philadelphia, PA 19104.Dr. Ginsberg: The Children's Hospital of Philadelphia, Division of Oncology, Colket Translational Research Building, 3501 Civic Center Boulevard, Room 10307, Philadelphia, PA 19104. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoGeneral Internists’ Preferences and Knowledge About the Care of Adult Survivors of Childhood Cancer Eugene Suh , Christopher K. Daugherty , Kristen Wroblewski , Hannah Lee , Mackenzie L. Kigin , Kenneth A. Rasinski , Jennifer S. Ford , Emily S. Tonorezos , Paul C. Nathan , Kevin C. Oeffinger , and Tara O. Henderson General Internists’ Preferences and Knowledge About the Care of Adult Survivors of Childhood Cancer Eugene Suh , Christopher K. Daugherty , Kristen Wroblewski , Hannah Lee , Mackenzie L. Kigin , Kenneth A. Rasinski , Jennifer S. Ford , Emily S. Tonorezos , Paul C. Nathan , Kevin C. Oeffinger , and Tara O. Henderson Metrics Cited byCare Coordination and Transitions of Care 7 January 2014Volume 160, Issue 1Page: 66-67KeywordsCancer treatmentChildrenHealth careHematology and oncologyLong-term careMedical educationPatient advocacyPediatric oncologyResidencyYoung adults ePublished: 7 January 2014 Issue Published: 7 January 2014 Copyright & PermissionsCopyright © 2014 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...