Chronic Hepatitis B in Asymptomatic Homosexual Men with Antibody to the Human Immunodeficiency Virus
Authors: Robert P. Perrillo, Fredric G. Regenstein, Stanford T. Roodman
Journal: Annals of Internal Medicine (1986)

Brief Reports1 September 1986Chronic Hepatitis B in Asymptomatic Homosexual Men with Antibody to the Human Immunodeficiency VirusROBERT P. PERRILLO, M.D., FREDRIC G. REGENSTEIN, M.D., STANFORD T. ROODMAN, Ph.D.ROBERT P. PERRILLO, M.D., FREDRIC G. REGENSTEIN, M.D., STANFORD T. ROODMAN, Ph.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-105-3-382 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe discovery of the human immunodeficiency virus (formerly known as HTLV-III/LAV) as the causative agent of the acquired immunodeficiency syndrome (AIDS) has led to the commercial availability of tests to detect antibody to one or more viral coded proteins. The most frequently used method is the enzyme-linked immunosorbent assay (ELISA), and reproducibly reactive tests done with this method are highly specific for antibody to the virus (1). In high-risk populations, such as homosexual men, the human immunodeficiency virus has been isolated from a single blood specimen in 67% to 95% of persons with a positive test for antibody (1, 2)....References1. . Recommendations for assisting in the prevention of perinatal transmission of human T-lymphotropic virus type III/lymphadenopathy-associated virus and acquired immunodeficiency syndrome. MMWR. 1985;34:721-6, 731-2. MedlineGoogle Scholar2. FEORINOJAFFEPALMER PHE. Transfusion-associated acquired immunodeficiency syndrome: evidence for persistent infection in blood donors. N Engl J Med. 1985;312:1293-6. CrossrefMedlineGoogle Scholar3. DIENSTAG J. Immunologic mechanisms in chronic viral hepatitis. In: VYAS GN, DIENSTAG, JL, HOOFNAGLE JH, eds. Viral Hepatitis and Liver Disease. Orlando, Florida: Grune & Stratton, Inc.; 1984:135-66. Google Scholar4. REICHERTO'LEARYLEVENSSIMRELLMACHER CTDCA. Autopsy pathology in the acquired immune deficiency syndrome. Am J Pathol. 1983;112:357-82. MedlineGoogle Scholar5. RUSTGIHOOFNAGLEGERIN VJJ. Hepatitis B virus infection in the acquired immunodeficiency syndrome. Ann Intern Med. 1984;101:795-7. LinkGoogle Scholar6. GLASGOWANDERSLAYFIELDSTEINSAPIRGITNICKLEWIN BKLKGK. Clinical and pathologic findings of the liver in the acquired immune deficiency syndrome (AIDS). Am J Clin Pathol. 1985;83:582-8. CrossrefMedlineGoogle Scholar7. DOBOZINJUDSONCOHN BFD. The relationship of abnormalities of cellular immunity to antibodies to HTLV III in homosexual men. Cell Immunol. 1986;98:156-71. CrossrefMedlineGoogle Scholar8. NOVICKLOKTHOMAS DAH. Diminished responsiveness of homosexual men to antiviral therapy for HBsAg-positive chronic liver disease. J Hepatol. 1984;1:29-35. CrossrefGoogle Scholar9. PERRILLOGELBCAMPBELL RLC. Hepatitis B e antigen, DNA polymerase activity, and infection of household contacts with hepatitis B virus. Gastroenterology. 1979;76:1319-25. CrossrefMedlineGoogle Scholar10. ALTERSEEFFKAPLAN HLP. Type B hepatitis: the infectivity of blood positive for e antigen and DNA polymerase after accidental needlestick exposure. N Engl J Med. 1976;295:909-13. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. 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WEISSBERG, M.D., MARK EISENBERG, M.D., JACK BISSETT, M.D., PREM V. NAIR, M.D., BARBARA MASTRE, R.N., SUE ROSNO, R.N., DEBBIE ROSKAMP, R.N., KAREN WATERMAN, R.N., RICHARD B. POLLARD, M.D., MYRON J. TONG, MD., Ph.D., BYRON W. BROWN Jr., Ph.D., WILLIAM S. ROBINSON, M.D., PETER B. GREGORY, M.D., THOMAS C. MERIGAN, M.D.Time for action on hepatitis B immunisation.Hepatitis in renal transplant recipients 1 September 1986Volume 105, Issue 3Page: 382-383KeywordsAIDSChronic hepatitis BEnzyme linked immunosorbent assayHIVHematologic testsHomosexualsPopulation statisticsProteins Issue Published: 1 September 1986 PDF DownloadLoading ...