The Relationship of "Chronic Pyelonephritis" to Chronic Potassium Deficiency
Authors: ROBERT C. MUEHRCKE
Journal: Annals of Internal Medicine (1963)

Article1 October 1963The Relationship of "Chronic Pyelonephritis" to Chronic Potassium DeficiencyROBERT C. MUEHRCKE, M.D., F.A.C.P., J. CHARLES MCMILLAN, M.D.ROBERT C. MUEHRCKE, M.D., F.A.C.P.Search for more papers by this author, J. CHARLES MCMILLAN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-59-4-427 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptPreliminary observations made in 1957, on patients chronically deficient of potassium suggested that chronic pyelonephritis was one sequel of chronic potassium deficiency (1, 2). At that time studies were also made of slides of renal tissue from such patients, which were sent to us by many colleagues in various parts of the world. In most sections "pyelonephritis" was noted. As a result of these observations, it does not seem to be unreasonable to postulate that the persistence of the multiple functional and structural derangement (Table 1, 1-20) noted in kidneys of man and animals with acute potassium deficiency might form...References1. MILNEMUEHRCKEHEARD MDRCBE: Potassium deficiency and the kidney. Brit. Med. Bull. 13: 15, 1957. CrossrefMedlineGoogle Scholar2. MUEHRCKEMILNE RCMD: Primary hyperaldosteronism, long standing potassium depletion and pyelonephritis. Clin. Res. 5: 190, 1957. Google Scholar3. RELMANSCHWARTZ ASWB: Nephropathy of potassium depletion: clinical and pathological entity. New Eng. J. Med. 225: 195, 1956. CrossrefGoogle Scholar4. SCHWARTZRELMAN WBAS: Metabolic and renal studies in chronic potassium depletion resulting from overuse of laxatives. J. Clin. Invest. 32: 258, 1953. CrossrefMedlineGoogle Scholar5. CONN JW: Primary aldosteronism: new clinical syndrome. J. Lab. Clin. Med. 45: 3, 1955. MedlineGoogle Scholar6. 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CHARLES MCMILLAN, M.D.Affiliations: Chicago, IllinoisFrom the Renal and Nutrition Unit, Division of Medicine, Presbyterian-St. Luke's Hospital; from the Departments of Medicine and Pathology, University of Illinois, College of Medicine, Chicago, Illinois; and from the Department of Medicine, West Suburban Hospital, Oak Park, Illinois.This work was supported by contract No. DA-49-007-MD-637 from the Surgeon General's Office, U. S. Army and by grant No. H-5529 from the United States Public Health Service, National Institutes of Health, Bethesda, Maryland.Requests for reprints should be addressed to R. C. Muehrcke, M.D., Presbyterian-St. Luke's Hospital, 1753 Congress Parkway, Chicago 12, Illinois. 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