Adrenal Steroids in the Treatment of Idiopathic Nephrotic Syndrome in Adults
Authors: H. RICHARD NESSON
Journal: Annals of Internal Medicine (1963)

Article1 February 1963Adrenal Steroids in the Treatment of Idiopathic Nephrotic Syndrome in AdultsH. RICHARD NESSON, M.D., L. EDWIN SPROUL JR., M.D., ARNOLD S. RELMAN, M.D., WILLIAM B. SCHWARTZ, M.D.H. RICHARD NESSON, M.D.Search for more papers by this author, L. EDWIN SPROUL JR., M.D.Search for more papers by this author, ARNOLD S. RELMAN, M.D.Search for more papers by this author, WILLIAM B. SCHWARTZ, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-58-2-268 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSteroids have been used extensively during the past decade in the treatment of adults with the idiopathic nephrotic syndrome (INS). However, evaluation of the reported results is difficult; definitions of "cure" have differed, and most studies have not provided comparable clinical and laboratory data.The purpose of this study is to report the results of treatment with adrenal steroids in 42 adults with INS and to consider these data in the light of what little is known about the natural history of this syndrome. The difficulties of assessing the role of steroids in the management of adult INS are pointed...References1. HARE RS: Endogenous creatinine in serum and urine. Proc. Soc. Exp. Biol. Med. 74: 148, 1950. CrossrefMedlineGoogle Scholar2. CHASSONGRADYSTANLEY ALHJMA: Determination of creatinine by means of automatic chemical analysis. Amer. J. Clin. Path. 35: 83, 1961. CrossrefGoogle Scholar3. GOODMANBAXTER HCJH: The nephrotic syndrome: clinical observations on therapy with prednisone and other steroids. JAMA 165: 1798, 1957. CrossrefMedlineGoogle Scholar4. 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CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Boston, MassachusettsFrom the Departments of Medicine, Boston University School of Medicine and the Tufts University School of Medicine; and from the Evans Memorial, Massachusetts Memorial Hospitals and the Pratt Clinic—New England Center Hospital, Boston, Massachusetts.Supported by training grant 2A-5209 from the National Institute of Arthritis and Metabolic Diseases (to Dr. Relman), and by training grant HTS-5309 from the National Heart Institute (to Dr. Schwartz).Requests for reprints should be addressed to Arnold S. Relman, M.D., Department of Clinical Research, Robert Dawson Evans Memorial, 65 East Newton Street, Boston 18, Massachusetts or to William B. Schwartz, M.D., New England Center Hospital, 171 Harrison Avenue, Boston 11, Massachusetts. 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POLLAK, M.D., F.R.C.P.(EDIN.), SEYMOUR ROSEN, M.D., CONRAD L. PIRANI, M.D., ROBERT C. MUEHRCKE, M.D., F.A.C.P., ROBERT M. KARK, M.D., F.A.C.P., F.R.C.P.Thrombosis, nephrosis, and corticosteroid therapySteroid Treatment of the Nephrotic Syndrome in AdultsA Nephrotic Syndrome in the Dog, Treated with PrednisoneCase 7-1966The Association of Cancer and the Nephrotic SyndromeJOHN C. LEE, M.D., H. YAMAUCHI, M.D., JAMES HOPPER JR., M.D.The management of childhood nephrosisCorticosteroid Therapy of Amyloid Nephrotic SyndromeMORTON H. MAXWELL, M.D., F.A.C.P., DONALD A. ADAMS, M.D., RALPH GOLDMAN, M.D., F.A.C.P.Normocholesterolemic nephrotic syndrome of systemic lupus erythematosusSteroids in the Nephrotic Syndrome 1 February 1963Volume 58, Issue 2Page: 268-277KeywordsClinical laboratoriesExcretionHeart diseasesHospital medicineMetabolic disordersProteinsProteinuriaResearch laboratoriesSteroid therapySteroids Issue Published: 1 February 1963 PDF DownloadLoading ...