Angiotensin-Converting Enzyme Inhibitors after Acute Myocardial Infarction
Authors: Ulrich Jorde
Journal: Annals of Internal Medicine (2005)

Letters4 January 2005Angiotensin-Converting Enzyme Inhibitors after Acute Myocardial InfarctionUlrich Jorde, MDUlrich Jorde, MDFrom New York University School of Medicine, New York, NY 10016.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-142-1-200501040-00018 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Pilote and colleagues (1) presented data suggesting that ramipril was superior to other angiotensin-converting enzyme (ACE) inhibitors after myocardial infarction. Their carefully discussed methods, in concert with the accompanying outstanding editorial (2), should confer the overall message that the study's design and limitations render its findings no more than hypothesis-generating. The authors rightfully pointed out that the distribution of observed mortality differences among the 7 ACE inhibitors studied is not consistent with any known pharmacologic property of these agents (that is, ACE inhibitors with higher tissue affinity did not consistently fare better than those with low tissue ...References1. Pilote L, Abrahamowicz M, Rodrigues E, Eisenberg MJ, Rahme E. Mortality rates in elderly patients who take different angiotensin-converting enzyme inhibitors after acute myocardial infarction: a class effect? Ann Intern Med. 2004;141:102-12. [PMID: 15262665] LinkGoogle Scholar2. Hennessy S, Kimmel SE. Is improved survival a class effect of angiotensin-converting enzyme inhibitors? [Editorial]. Ann Intern Med. 2004;141:157-8. [PMID: 15262673] LinkGoogle Scholar3. Summaries for patients. ACE inhibitors after heart attacks: varying effects? Ann Intern Med. 2004;141:I34. [PMID: 15262682] LinkGoogle Scholar4. Jorde U. AJC. In press. Google Scholar Author, Article, and Disclosure InformationAuthors: Ulrich Jorde, MDAffiliations: From New York University School of Medicine, New York, NY 10016. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoMortality Rates in Elderly Patients Who Take Different Angiotensin-Converting Enzyme Inhibitors after Acute Myocardial Infarction: A Class Effect? Louise Pilote , Michal Abrahamowicz , Eric Rodrigues , Mark J. Eisenberg , and Elham Rahme Is Improved Survival a Class Effect of Angiotensin-Converting Enzyme Inhibitors? Sean Hennessy and Stephen E. Kimmel ACE Inhibitors after Heart Attacks: Varying Effects?Angiotensin-Converting Enzyme Inhibitors after Acute Myocardial Infarction Heather L. Horton Angiotensin-Converting Enzyme Inhibitors after Acute Myocardial Infarction Louise Pilote and Michal Abrahamowicz Metrics 4 January 2005Volume 142, Issue 1Page: 78KeywordsACE inhibitorsAcute myocardial infarctionCongestive heart failureExercise therapyHeart failureLongitudinal studiesMortalityMyocardial infarctionRandomized trialsStatins ePublished: 4 January 2005 Issue Published: 4 January 2005 Copyright & PermissionsCopyright © 2005 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...