Development of Atherosclerosis in a Saphenous Vein Coronary Bypass Graft
Authors: JOHN FARRY
Journal: Annals of Internal Medicine (1976)

Letters1 October 1976Development of Atherosclerosis in a Saphenous Vein Coronary Bypass GraftJOHN FARRY, M.D., GRAEME L. HAMMOND, M.D., LAWRENCE S. COHEN, M.D., F.A.C.P., STEVEN WOLFSON, M.D., F.A.C.P.JOHN FARRY, M.D.Search for more papers by this author, GRAEME L. HAMMOND, M.D.Search for more papers by this author, LAWRENCE S. COHEN, M.D., F.A.C.P.Search for more papers by this author, STEVEN WOLFSON, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-85-4-478 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptStudies of aortocoronary saphenous vein bypass grafts have shown that those patients with initially patent grafts have a good prognosis for long-term patency (1). The grafts that occlude after the immediate postoperative period usually show obliteration of the vessel lumen by abnormal concentric intimal thickening (2, 3). This report documents the development of overt fully developed atherosclerotic lesions in a saphenous vein graft 4 years after surgical insertion.The patient is a 49-year-old white man with a 10-year history of angina pectoris and two subendocardial myocardial infarctions between 1965 and 1970. He smoked heavily, had a family history of artherosclerotic...References1. GRONDINLESPéRANCEBOURASSA CJM: Serial angiographic evaluation in 60 consecutive patients with aortocoronary vein grafts 2 weeks, 1 year, and 3 years after operation. J Thorac Cardiovasc Surg 67:1-6, 1974. CrossrefMedlineGoogle Scholar2. UNNIKOTTKETITUS KBJ: Pathologic changes in aortocoronary saphenous vein grafts. Am J Cardiol 34:526-532, 1974 CrossrefMedlineGoogle Scholar3. KERNDERMERLINDESMITH WGG: The intimai proliferation in aortic-coronary saphenous vein grafts. Light and electron microscopic studies. Am Heart J 84:771-777, 1972 CrossrefMedlineGoogle Scholar4. ROSSGLOMSET RJ: Atherosclerosis and the arterial smooth muscle cell. Proliferation of smooth muscle is a key event in the genesis of the lesions of atherosclerosis. Science 180:1332-1339, 1973 CrossrefMedlineGoogle Scholar5. ALLARDGOULETGROUNDIN CCM: Patency of aortocoronary vein grafts and serum triglycerides. Three year follow-up study. Am J Cardiol 33:679-680, 1974 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Departments of Medicine (Cardiology) and Pathology Section of Cardiothoracic Surgery Yale-New Haven Hospital New Haven, CT 06510 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe effect of antiaggregating drugs on the patency of grafts in the arterial systemAtherosclerotic changes in coronary vein grafts six years after operationPatency of saphenous vein grafts five or more years after coronary bypass surgeryThe internal mammary bypass graft: A superior second coronary artery 1 October 1976Volume 85, Issue 4Page: 478-479KeywordsAnginaAtherosclerosisLesionsMyocardial infarctionStable coronary artery diseaseVeins Issue Published: 1 October 1976 PDF downloadLoading ...