tbuckley/cabot-search huggingface dataset:
Cutaneous Fistula Communicating with the Hip in a Patient with a Painful Total Hip Prosthesis Demonstration by Radionuclide Arthrography
Authors: CHANDRU U. JAIN, DAVID C. YANG, DEVAYANI M. PATEL, KOPRESH A. GUDI, JOSEPH GIOVANNIELLO
Journal: Clinical Nuclear Medicine (1988)

Radionuclide arthrography is becoming increasingly useful in the evaluation of femoral component loosening in patients with a painful total hip prosthesis. Additional potential advantages of radionuclide arthrography include detection of abnormal communications with the hip, such as bursae, abscess cavities, and fistulas. A case of cutaneous fistula communicating with the hip in a patient with loosening and infection of the femoral component of the total hip prosthesis that is clearly demonstrated by radionuclide arthrography is presented.
Prone Positioning in Children With ARDS
Authors: Brian P. Kavanagh
Journal: JAMA (2005)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Patient-to-patient transmission of hepatitis C virus
Authors: Jean Marc Durand, Patrice Lefevre, Gilles Kaplanski, Jacques Soubeyrand, Tobias Allander, Astrid Gruber, MatsA.A. Persson, Giovanni Calabrese, Giuseppe Vagelli, Marco Gonella, ElizabethA.B. McCruden, June Munro, Bruce King, Sharon Fitzpatrick, J. Douglas Briggs, D. Klarmann, W. Kreuz, K. Auberger, G. Auerswald, E. Lenz, W. Roth, B. Kornhuber
Journal: The Lancet (1995)
On Real-Time Estimates of Blood Glucose Levels
Authors: Satish K. Garg
Journal: Diabetes Care (2007)

In the comment from Trevino (1), three articles are cited as having “emphasized the need for real-time assessment of blood glucose levels.” Two of the cited articles (2,3) indeed relate to real-time assessment of blood glucose levels using new technology referred to as continuous glucose monitoring (CGM). The third article Trevino refers to, by Farmer et al. (4), relates to the use of traditional finger-stick blood analysis that is communicated to a nurse via telemedicine. We are engaged in the study of CGM, so further comments will be related only to continuous sensors (2,3) and not to telemedicine.

Trevino further states that “[r]eal-time analysis is motivated by the belief that the random time series being analyzed manifests average properties that change with the passage of time. Results of such analyses are presented to patients as means (μ) ± SD.” In regard to our study (2), this statement is completely false. We do not rely on averaged properties of time series data. Patients received actual glucose concentration values transmitted every 5 min. Under no circumstances were patients presented with the mean and SD of the data in real time.

Trevino further describes an equation for determining mean and SD and …
A Multivariate Logistic Regression Equation to Screen for Diabetes
Authors: Stéphane Roze, Andrew J. Palmer, William J. Valentine
Journal: Diabetes Care (2003)

We read the article by Tabaei and Herman (1) in the November 2002 issue of Diabetes Care with great interest and feel that it covers an exciting and vital area of diabetes research. We applaud the authors’ attempts to improve current standards of diabetes screening and the journal’s willingness to publish important new findings in the field. However, when we reviewed the article, we found the results difficult to reproduce, especially as there were no numerical examples provided in the text. Using the precise formula given in the article, our calculations produced negative probability values. We …
Hold the antioxidants and improve plasma lipids?
Authors: Ronald M. Krauss
Journal: Journal of Clinical Investigation (2004)

Intrahepatic proteolysis is a major determinant of secretion of ApoB-containing lipoproteins into plasma. Stimulation of post-ER presecretory proteolysis (PERPP) of ApoB by n-3 polyunsaturated fatty acids has been found to result in reduced secretion of VLDL particles by hepatocytes. A new study has shown that this stimulation is promoted by pro-oxidant conditions that result in increased hepatic lipid hydroperoxide content. Conversely, PERPP is suppressed by antioxidants and by saturated fatty acids, which are not susceptible to lipid peroxidation. Hence reduction of oxidative stress may have the unexpected side effect of increasing plasma lipid levels.
not all categories work the same way
Authors: sidney r. lehky
Journal: Behavioral and Brain Sciences (2005)

the relative contributions of biological and cultural factors in determining category characteristics almost certainly vary for different categories, so that the results of these simulations on color categories don't necessarily generalize. it is suggested here that categories that pick out structure in the environment of strong behavioral significance to individual agents will be predominantly biologically determined and will converge without interagent communication, whereas those categories that serve primarily to coordinate behavior in a population will require communication to converge.
CTLA-4 recipient polymorphism influences HCV liver disease recurrence following orthotopic liver transplantation (OLT)
Authors: Luca Valenti, Vittoria Spatola, Erika Fatta, Paola Dongiovanni, Giorgio Rossi, Gemino Fiorelli, Luigi Rainero Fassati, Silvia Rossana Fargion
Journal: Journal of Hepatology (2002)
Right atrial-pulmonary artery anastomosis: a historical note.
Authors: D E Cassels, P V Moulder
Journal: Thorax (1979)

Right atrial-pulmonary artery anastomosis: a historical note Sir,-In 1966 a short case report on this subject was included in a paper entitled "New operations in children's cardiac disease," published in Surgical Clinics of North America (Rams et al, 1966).This case report was entitled "Total correction of tricuspid atresia" and concerned a girl, aged 16 months, who had a Glenn procedure in October 1958.In 1960 a right atrial-pulmonary artery anastomosis was per- formed, as shown in fig 7 of the paper.In April 1961 the atrial septal defect was closed.She did well for 24 hours, but then developed renal failure and hyper- kalaemia and had a cardiac arrest.Figure 1 is from the 1966 publication with labels to correspond to those of fig 2, the anatomical specimen.
Case of Gangrene of the Lower Extremities Following a Blow on the Epigastrium: Double Amputation and Remarks
Authors: G. Curtis
Journal: BMJ (1889)

went on to their home to obtain a horse on which to deliver the patient to his friends.By these arrangements small-pox com- menced its ravages at two centres at the same time.On visiting the home of the importer of the disease shortly after his arrival, seventeen individuals were found affected,3 occupying ten huts, all within a radius of 100 yards.In order to limit the spread of the contagion, sentinels were posted in a ring around the area in which those suffering were residing, so as to prevent ingress and egress.In assisting me to appoint men for such duty, the petty chief showed ingenuity in picking out only those who were young, handsome, and unmarried, remarking that such would be least likely to sleep at their posts.More to be relied on than quarantine we urged on the neighbours the importance of vaccination, and accordingly a few child- ren just outside the cordon were operated on; from these on the eighth day more could be protected, and by the third week there was sufficient virus at hand for the needed purpose.By these means the outbreak did not spread beyond its original limits.With the same malady epidemic in various parts of the adjacent territories, and the natives constantly moving about, it was not to be wondered at that in several quarters the contagion was re- peatedly reintroduced into our district.In all cases the precau- tionary measures mentioned were adopted.Sometimes one was fortunate enough to check an eruption at its birth by timely vaccination of those in immediate contact with the victim of the disease.Now and then both vaccination and small-pox ran their course together in the same individual, the former having been administered too many days after exposure to the germs of the disease.Those who, inside quarantine limits, were successfully vaccinated were able to stand as severe a test as could be devised, as they lived in the same huts as the patients, and nursed and tended them.I have no single note of any unvaccinated person enclosed in a quarantine line escaping the disease; while, on the other hand, the numerous instances occurring during many months of vaccinated people being enclosed with those dying of the pest, and yet escaping all illness, opened the eyes of the savages to the value of Jenner's discovery.
Atherosclerosis
Authors: Denham Harman
Journal: Circulation Research (1962)

Young, rapidly growing rabbits developed more aortic atherosclerosis on an ad libitum cholesterol-containing diet than did older, more slowly growing rabbits. This effect may be due to an affinity of newly formed tissue, produced during growth, for lipids; this may be a partial explanation of the increase in the number of fatty streaks seen around the age of puberty in humans. A possible mechanism, based on local aortic injury, is presented to account for the localization and development of human atherosclerotic lesions.
Safety, Pharmacokinetics, and Pharmacodynamics of the Insulin-Like Growth Factor Type 1 Receptor Inhibitor Figitumumab (CP-751,871) in Combination with Paclitaxel and Carboplatin
Authors: Daniel D. Karp, Michael N. Pollak, Roger B. Cohen, Peter D. Eisenberg, Paul Haluska, Donghua Yin, Allan Lipton, Laurence Demers, Kim Leitzel, Mary L. Hixon, Leon W. Terstappen, Linda Garland, Luis G. Paz-Ares, Felipe Cardenal, Corey J. Langer, Antonio Gualberto
Journal: Journal of Thoracic Oncology (2009)
Enhanced cyclooxygenase-1 expression within the superior mesenteric artery of portal hypertensive rats: Role in the hyperdynamic circulation
Authors: Ming-Chih Hou, Paul A. Cahill, Shuangmin Zhang, Yi-Ning Wang, Richard J. Hendrickson, Eileen M. Redmond, James V. Sitzmann
Journal: Hepatology (1998)

Portal hypertension (PHT) is characterized by splanchnic hyperemia due to enhanced production of vasodilator substances. Enhanced vasodilation and increased splanchnic blood flow contribute to the elevated portal pressure characteristic of PHT. The aim of this study was to determine whether cyclooxygenase (Cox) expression is altered in PHT vessels and whether chronic inhibition of this enzyme impacts on splanchnic blood flow in PHT. PHT was created in Sprague-Dawley rats by a partial portal vein ligation. Control animals were sham operated. Plasma 6-keto-PGF 1 α (prostaglandin F 1 α) levels were significantly elevated in PHT after 2 days as compared with sham and remained elevated up to day 15. Treatment with indomethacin (2 mg/kg ip daily for 15 days) resulted in a significant decrease in 6-keto-PGF 1 α levels, which was concomitant with a significant decrease in superior mesenteric artery blood flow (Qsma) after 15 days in PHT rats. Cox-I expression was differentially enhanced in the PHT superior mesenteric artery and thoracic aorta during the development and progression of PHT. In contrast, Cox-II messenger RNA (mRNA) and protein expression was not detected in either of these vessels throughout the development of PHT. These data suggest that PHT is associated with enhanced Cox-I expression within the splanchnic vasculature concomitant with elevated plasma prostacyclin levels and a significant pressor response to indomethacin in PHT animals. We conclude that enhanced Cox-I expression results in increased prostacyclin levels that partially contribute to the maintenance of the hyperemia typical of PHT.
Life expectancy and mortality data from the Soviet Union
Authors: M. Ryan
Journal: BMJ (1988)

Recent official data on mortality in the USSR are summarized. The data concern regional differences in life expectancy and infant mortality as well as age-specific death rates.  The author notes that although Soviet mortality trends have begun to improve after worsening in the 1970s and early 1980s Soviet authorities remain concerned over the need to make further improvements in the health of the population particularly in comparison with other countries.  (ANNOTATION)
BBS10 encodes a vertebrate-specific chaperonin-like protein and is a major BBS locus
Authors: Corinne Stoetzel, Virginie Laurier, Erica E Davis, Jean Muller, Suzanne Rix, José L Badano, Carmen C Leitch, Nabiha Salem, Eliane Chouery, Sandra Corbani, Nadine Jalk, Serge Vicaire, Pierre Sarda, Christian Hamel, Didier Lacombe, Muriel Holder, Sylvie Odent, Susan Holder, Alice S Brooks, Nursel H Elcioglu, Eduardo D Silva, Béatrice Rossillion, Sabine Sigaudy, Thomy J L de Ravel, Richard Alan Lewis, Bruno Leheup, Alain Verloes, Patrizia Amati-Bonneau, André Mégarbané, Olivier Poch, Dominique Bonneau, Philip L Beales, Jean-Louis Mandel, Nicholas Katsanis, Hélène Dollfus
Journal: Nature Genetics (2006)
Positive-Pressure Ventilation in Amyotrophic Lateral Sclerosis
Authors: Marcia Bio
Journal: Annals of Internal Medicine (1998)

Letters1 April 1998Positive-Pressure Ventilation in Amyotrophic Lateral SclerosisMarcia Bio, MD and John R. Bach, MDMarcia Bio, MDUniversity of Medicine and Dentistry of New Jersey Medical School; Newark, NJ 07103Search for more papers by this author and John R. Bach, MDUniversity of Medicine and Dentistry of New Jersey Medical School; Newark, NJ 07103Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-128-7-199804010-00025 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Although Aboussouan and colleagues [1] reaffirm that assisting the ventilation of patients with amyotrophic lateral sclerosis can prolong survival, even their patients who “tolerated” nocturnal nasal positive-pressure ventilation survived only 15 months. Most untreated patients with this disease die of CO2 narcosis or inability to clear airway secretions [2]. However, patients for whom assisted peak cough flows greater than 160 L/min can be generated (that is, patients with less bulbar involvement) and who are equipped and trained in using assisted coughing, mechanical insufflation-exsufflation, and up to 24-hour non-invasive positive-pressure ventilation as needed can have prolonged survival without ...References1. Aboussouan LS, Khan SU, Meeker DP, Stelmach K, Mitsumoto H. Effect of noninvasive positive-pressure ventilation on survival in amyotrophic lateral sclerosis. Ann Intern Med. 1997; 127:450-3. Google Scholar2. Bach JR, Pansit R, Ballanger F, Kulessa R, Ishikawa Y. Neuromuscular ventilatory insufficiency: the effect of home mechanical ventilator use vs. oxygen therapy on pneumonia and hospitalization rates. Am J Phys Med Rehabil. [In press]. Google Scholar3. Bach JR. Amyotrophic lateral sclerosis: predictors for prolongation of life by noninvasive respiratory aids. Arch Phys Med Rehab. 1995; 76:828-31. Google Scholar4. Bach JR, Saporito LR. Criteria for extubation and tracheostomy tube removal for patients with ventilatory failure: a different approach to weaning. Chest. 1996; 110:1566-71. Google Scholar5. Bach JR, ed. Pulmonary Rehabilitation: The Obstructive and Paralytic Conditions. Philadelphia: Hanley & Belfus; 1996. Google Scholar Author, Article, and Disclosure InformationAuthors: Marcia Bio, MD; John R. Bach, MDAffiliations: University of Medicine and Dentistry of New Jersey Medical School; Newark, NJ 07103 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 April 1998Volume 128, Issue 7Page: 601-602KeywordsAmyotrophic lateral sclerosisCoughingHospitalizationsIntubationMouthMucusRespiratory failureTidal volumeTracheostomyVentilatory support ePublished: 15 August 2000 Issue Published: 1 April 1998 Copyright & PermissionsCopyright © 1998 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Selective Roentgenographic Contrast Examination and Electrokymography of the Left Heart in Experimental Mitral Insufficiency
Authors: BJÖRN NORDENSTRÖM, J. P. STAMER, MELVIN FIGLEY, HERBERT SLOAN
Journal: Circulation (1957)

Difficulty in the accurate preoperative assessment of mitral insufficiency, clinically and by several laboratory methods, suggested the desirability of direct visualization of the regurgitant flow. Direct puncture of the left ventricle for the injection of radiopaque contrast material was used in dogs before and after the creation of mitral insufficiency by division of 1 chorda tendinea. The regurgitation was accurately recognized radiographically. Consistent alterations in left atrial border movement were also recorded by electrokymography.
Defective mast cell effector functions in mice lacking the CRACM1 pore subunit of store-operated calcium release–activated calcium channels
Authors: Monika Vig, Wayne I DeHaven, Gary S Bird, James M Billingsley, Huiyun Wang, Patricia E Rao, Amy B Hutchings, Marie-Hélène Jouvin, James W Putney, Jean-Pierre Kinet
Journal: Nature Immunology (2007)
Modeling complex decay profiles of hepatitis B virus during antiviral therapy
Authors: Harel Dahari, Emi Shudo, Ruy M. Ribeiro, Alan S. Perelson
Journal: Hepatology (2008)

Typically, hepatitis B virus (HBV) decays in patients under therapy in a biphasic manner. However, more complex decay profiles of HBV DNA (e.g., flat partial response, triphasic, and stepwise), for which we have no clear understanding, have also been observed in some treated patients. We recently introduced the notion of a critical drug efficacy, epsilon(c), such that if overall drug efficacy, epsilon(tot), is higher than the critical drug efficacy (i.e., epsilon(tot) > epsilon(c)) then viral levels will continually decline on therapy, while if epsilon(tot) < epsilon(c), then viral loads will initially decline but will ultimately stabilize at a new set point, as seen in flat partial responders. Using the idea of critical efficacy and including hepatocyte proliferation in a viral kinetic model, we can account for these complex HBV DNA decay profiles. The model predicts that complex profiles such as those exhibiting a plateau or shoulder phase, as well as a class of stepwise declines, occur only in patients in whom the majority of hepatocytes are infected before therapy.We show via kinetic modeling how a variety of HBV DNA decay profiles can arise in treated patients.
In vitro–in vivo correlation for wet-milled tablet of poorly water-soluble cilostazol
Authors: Jun-ichi Jinno, Naoki Kamada, Masateru Miyake, Keigo Yamada, Tadashi Mukai, Masaaki Odomi, Hajime Toguchi, Gary G. Liversidge, Kazutaka Higaki, Toshikiro Kimura
Journal: Journal of Controlled Release (2008)
Pericarditis As a Complication of Meningococcal Meningitis
Authors: JOHN R. MORSE
Journal: Annals of Internal Medicine (1971)

Pericarditis complicating the course of meningococcal meningitis is a distinctly uncommon event. A total of 32 cases of meningococcal meningitis were encountered over a 13-month period. Six of these developed acute pericarditis during the convalescent phase of their disease, for an incidence of 19%. Fever, chest pain, friction rub, and typical ECG changes were the common diagnostic findings in all cases. The clinical course of these patients was generally benign, with a variable but complete response to anti-inflammatory medications. Only one patient developed pericardial compression necessitating pericardiocentesis. Speculation as to causes for increased incidence of this complication includes the possibility
Experimentation in Medical History-Taking
Authors: Donald W. Simborg
Journal: JAMA (1969)

The traditional dialogue technique used by physicians to obtain a medical history is time-consuming and cumbersome to record. The use of quesionnaires and automated devices to perform these functions for the physician is being tested by numerous investigators. These newer techniques have been shown to be superior to the physician's dialogue history in terms of providing a recorded data base of patient information for future retrieval. They also enable easy collection of statistical information about symptomatology in diseases. However, there is no information available as to whether they better enable the physician to make an assessment of the patient's condition with respect to initial diagnostic and therapeutic decisions. Thus, at this time, they cannot be considered as a substitute for the physician-obtained medical history.
Influence of Alexithymia on Symbolic Function
Authors: Louise Demers-Desrosiers
Journal: Psychotherapy and Psychosomatics (1982)

The archetypal test with nine elements (AT9), specifically designed as a tracer of symbolic function, and the psychosomatic questionnaire of Sifneos et al., for assessment of alexithymia, were both proposed within the context of a psychosomatic consultation to 49 hospitalized patients being investigated for physical symptoms representative of psychosomatic problems at large. The AT9 test enables the utilization of G. Durand's theory of the Anthropological Structures of the Imaginary, and was our theoretical support to engage upon an empirical study in the hope of contributing to the debate about the influence of alexithymia on symbolic function. Faced with the AT9 aim of having to create a mythical micro-universe through three tasks: a drawing, a story, and answers to a questionnaire, the patients exhibited different behaviors. 13 of 49 patients were found not to be alexithymic, and their symbolic function was totally comparable to a normal population. The other 36 patients were found to be alexithymic in increasing degrees, and the symbolic function was found to be abnormal in all the protocols studied. The greatest abnormality was seen in patients who scored 7-8 on the alexithymia scale where 12 of the 18 protocols showed no evidence whatsoever of a mythical micro-universe. We suggest that alexithymia does influence the symbolic function and disorganizes it the more one is alexithymic. Also depending on the type of symbolic function put forth, we would like to propose graphic documents to illustrate Freyberger's intuition about a distinction to be made within the alexithymic population between a primary and secondary form.