Herpes Zoster: Transfer Factor Therapy
Authors: W. LAWRENCE DREW
Journal: Annals of Internal Medicine (1973)

Letters1 November 1973Herpes Zoster: Transfer Factor TherapyW. LAWRENCE DREW, M.D., PH.D., MYRON R. BLUME, M.D., PH.D., RICHARD MINER, B.A., IVAN SILVERBERG, M.D., ERNEST H. ROSENBAUM, M.D., F.A.C.P.W. LAWRENCE DREW, M.D., PH.D.Search for more papers by this author, MYRON R. BLUME, M.D., PH.D.Search for more papers by this author, RICHARD MINER, B.A.Search for more papers by this author, IVAN SILVERBERG, M.D.Search for more papers by this author, ERNEST H. ROSENBAUM, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-79-5-747 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Varicella-zoster virus infections are potentially lethal in patients with defective cell-mediated immunity. Such susceptibility might be "repaired" by transfer factor. We have attempted to treat disseminated herpes zoster with transfer factor from a donor whose lymphocytes reacted in vitro to varicella-zoster antigen.A man, 44 years old, with Hodgkin's disease, stage IVB, was hospitalized with disseminated herpes zoster. His generalized vesicular lesions showed little evidence of crusting and healing. Fluorescent antibody examination of a skin lesion was positive for varicella-zoster, and the virus was cultured from a skin lesion. The leukocyte count was 5700/mm3, with 75% polymorphonuclear...References1. LAWRENCE H, AL-ASKARI S, and DAVID J: Transfer of immunoinformation in humans with dialysates of leukocyte extracts. Trans Assoc Am Physicians 76:84-91, 1963 Google Scholar2. BLUME M: Methods in Cancer Research, vol. 9. New York, Academic Press, Inc., 1973. In press Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: W. LAWRENCE DREW, M.D., PH.D.; MYRON R. BLUME, M.D., PH.D.; RICHARD MINER, B.A.; IVAN SILVERBERG, M.D.; ERNEST H. ROSENBAUM, M.D., F.A.C.P.Affiliations: Department of Pathology and Laboratory Medicine Immunology Research Laboratory Medical Oncology Service Mount Zion Hospital and Medical Center San Francisco, California PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byOptical Physics of Interference Pearl PigmentsImmune Modulators as Antiviral AgentsVaricella—Herpes Zoster VirusVaricella—Herpes Zoster VirusImmunology of Varicella-Zoster VirusTransfer Factor and Its Clinical ApplicationTransfer factorA double-blind evaluation of transfer factor therapy of HBsAg-positive chronic aggressive hepatitis: Preliminary report of efficacyA study of transfer factor for opportunistic infections in cancer patientsCOMPARISON OF DIFFERENT MODES OF LYMPHAPHERESIS FOR TRANSFER FACTORMANAGEMENT OF VIRAL INFECTIONS WITH TRANSFER FACTOREXPERIMENTS TO PREVENT HERPESVIRUS SAIMIRI INDUCED LYMPHOMA IN MARMOSETS WITH NONHUMAN PRIMATE TRANSFER FACTOR AND IMMUNE RNATRANSFER FACTOREffect of Transfer Factor and Zoster Immunoglobulin in Patients with Varicella-Zoster Infection and MalignancyBiological and Clinical Aspects of Transfer FactorTransfer factor treatment of chronic mucocutaneous candidiasis: Requirement for donor reactivity to Candida antigenImmunotherapy of viral infections with transfer factorHerpes zoster and impaired cell-associated immunity to the varicella-zoster virus in patients with Hodgkin's diseaseThe demonstration of cell-associated immunity to viruses. In vitro lymphocyte responsiveness to varicella-zoster antigenPREVENTION OF HERPES SIMPLEX VIRUS TYPE 1 FATAL DISSEMINATION IN PRIMATES WITH HUMAN TRANSFER FACTORTransfer Factor and Cellular Immunity to Viral Infection 1 November 1973Volume 79, Issue 5Page: 747-748KeywordsAntigensCell mediated immunityHodgkin lymphomaLesionsLymphocytesVaricella zoster virus ePublished: 1 December 2008 Issue Published: 1 November 1973 PDF downloadLoading ...