MALIGNANT MONOBLASTOMA
Authors: LOUIS A. MITCHELL
Journal: Annals of Internal Medicine (1935)

Article1 May 1935MALIGNANT MONOBLASTOMAA VARIANT OF MONOCYTIC LEUKEMIA*LOUIS A. MITCHELL, M.D.LOUIS A. MITCHELL, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-8-11-1387 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn 1913 Reschad and Schilling-Torgau1 reported the first case of monocytic leukemia to appear in the literature. Since then the disease has gradually gained recognition, and variations from its usual form, such as are found in association with other types of leukemia, have been observed. However, extensive tumor formation with primary multiple monoblastomata of the connective tissues ending in a terminal leukemic phase in which large numbers of primitive monoblasts flooded the peripheral circulation, such as is herewith described, has not previously been reported.The acceptance of monocytic leukemia as a distinct disease has come through a recognition of the...Bibliography1. RESCHADSCHILLING-TORGAU HV: Über eine neue Leukämie echte Übergangsformen (Splenozytenleukämie) und ihre Bedeutung für die Selbstandigkeit dieser Zellen, München. med. Wchnschr., 1913, lx, 1981-1984. Google Scholar2. FORKNER CE: Clinical and pathologic differentiation of acute leukemias, Arch. Int. Med., 1934, liii, 1-34. CrossrefGoogle Scholar3. MAXIMOW AA: A text-book of histology, 1930, W. B. Saunders Co., Philadelphia. Google Scholar4. NAEGELI O: Blutkrankheiten und Blutdiagnostik, 1931, J. Springer, Berlin. CrossrefGoogle Scholar5. CUNNINGHAMSABINDOAN RSFRCA: The development of leukocytes, lymphocytes and monocytes from a specific stem cell in the adult tissues, Carnegie Inst. Wash., Contrib. to Embryol., 1925, No. 83, p. 163. Google Scholar6. SABINDOANCUNNINGHAM FRCARS: Discrimination of two types of phagocytic cells in the connective tissues by the supravital technic, Carnegie Inst. Wash., Contrib. to Embryol. Google Scholar7. SWIRTSCHEWSKAJA B: Über leukämische Retikuloendotheliose, Virchow's Arch. f. path. Anat., 1928, cclxvii, 456-476. CrossrefGoogle Scholar8. FONTANA : A proposito della leucemia monocitica, Minerva med., 1932, ii, 673-678. Google Scholar9. FOORDPARSONSBUTT AGLEM: Leukemic reticulo-endotheliosis, Jr. Am. Med. Assoc., 1933, ci, 1859-1866. CrossrefGoogle Scholar10. DOANWISEMAN CABK: The monocyte, monocytosis, and monocytic leukosis; a clinical and pathological study, ANN. INT. MED., 1934, viii, 383-416. Google Scholar11. MARCHALBARGETON G: Difficultés de diagnostic entre maladie de Hodgkin et leukémie à monocytes, Sang, 1933, vii, 321-327. Google Scholar12. LASOWSKY JM: Über eine systembezogene blastomartige Hyperplasie des Reticuloendotheliums (sog. Reticuloendotheliom), Virchow's Arch. f. path. Anat., 1933, cclxxxviii, 631-640. CrossrefGoogle Scholar13. SYDENSTRICKERPHINIZY VPTB: Acute monocytic leukemia; case with partial autopsy, Am. Jr. Med. Sci., 1932, clxxxiv, 770-777. CrossrefGoogle Scholar14. WYRCHEGORODZEWA : Zur Frage der monozytaren Leukämie, Folia haemat., 1929, xxxviii, 355-366. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: LOUIS A. MITCHELL, M.D.Affiliations: Newark, Ohio*Received for publication January 8, 1935.From the Pathological Laboratories of the Newark City Hospital, Newark, Ohio. Nextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byBIBLIOGRAPHYPruritus and nonspecific nodules preceding myelomonocytic leukemiaNon-Hodgkin's lymphoma and acute myeloblastic leukemia.A report of 12 cases and review of the literatureLeukämienMethodologic Prerequisites for a Differential Diagnosis of LymphomasClassification of Non-Hodgkin’s LymphomasHistopathology and Diagnosis of Non-Hodgkin’s LymphomasTransformation of reticulum cell sarcoma to acute leukemiaOrbital Lymphoblastomas and Acute Leukemias in Children*Studies on the comparative morphology of monocytic leukemia, granulocytic leukemia, and reticulum-cell sarcomaMonocytic leukemiaBlood Dyscrasias As Related to Periodontal Disease: With Special Reference to LeukemiaDie funktionell-pathologischen Beziehungen zwischen aplastischer Anämie und akuten LeukämienErgebnisse der Leukoseforschung der letzten JahreDie akuten LeukämienHematology and pathology of leucemic reticuloendotheliosis 1 May 1935Volume 8, Issue 11Page: 1387-1403 ePublished: 1 December 2008 Issue Published: 1 May 1935 PDF downloadLoading ...