Alpha-Interferon for the Hypereosinophilic Syndrome
Authors: F.W. Busch, H. Schmidt, B. Steinke
Journal: Annals of Internal Medicine (1991)

Letters15 February 1991Alpha-Interferon for the Hypereosinophilic SyndromeF.W. Busch, MD, H. Schmidt, MD, B. Steinke, MDF.W. Busch, MDSearch for more papers by this author, H. Schmidt, MDSearch for more papers by this author, B. Steinke, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-114-4-338_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editors:Zielinski and Lawrence (1) reported the case of a patient with the hypereosinophilic syndrome who was successfully treated with interferon-á. Independently of their studies, we initiated interferon-á therapy in two patients with this syndrome who could not be managed with conservative treatment. Both patients had the syndrome according to standard criteria (2), and chromosomal abnormalities had been ruled out by repeated cytogenetic analyses (courtesy of Professor Fonatsch, Lübeck, Federal Republic of Germany). Organ involvement included restrictive endomyocardiopathy and right ventricular failure in both patients. Patient A, a 48-year-oldman, also developed recurring diarrhea that was interpreted as a...References1. ZielinskiLawrence RW. Interferon-á for the hypereosinophilic syndrome. Ann Intern Med. 1990;113:716-8. LinkGoogle Scholar2. FauciHarleyRobertsFerransGralnickBjornson AJWVHB. The idiopathic hypereosinophilic syndrome. Ann Intern Med. 1982;97:78-92. LinkGoogle Scholar3. MurphyFennellyStuartO'Donnell PDMJ. Alfa-interferon in a case of hypereosinophilic syndrome. Br J Haematol. 1990;75:619-20. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Medizinische Universitätsklinik 74 Tübingen Federal Republic of Germany PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byGuideline for the investigation and management of eosinophiliaUse of pegylated interferon in hypereosinophilic syndromeTreatment of Hypereosinophilic Syndromes with Prednisone, Hydroxyurea, and InterferonAtypical Myeloproliferative Disorders: Diagnosis and ManagementInterferon Treatment for Hypereosinophilic Syndromes and Systemic MastocytosisModern Diagnosis and Treatment of Primary EosinophiliaComplete Remission of Hypereosinophilic Syndrome after Interferon-α Therapy: Report of a Case and Literature ReviewSuccessful Pregnancy in a Woman with Cyclic Angioedema and EosinophiliaSuccessful bone marrow transplantation for idiopathic hypereosinophilic syndromeEosinophils: Biology and Role in DiseaseAlpha interferon for hypereosinophilic syndromeResponse of six patients with idiopathic hypereosinophilic syndrome to interferon alfa*α-Interferon treatment for idiopathic hypereosinophilic syndromeHypereosinophilic syndromes: an update 15 February 1991Volume 114, Issue 4Page: 338-339KeywordsChromosomesCytogeneticsDiarrheaPatient advocacyPatients Issue Published: 15 February 1991 PDF downloadLoading ...