Chronic Neutrophilic Leukemia
Authors: HARRY RUBIN
Journal: Annals of Internal Medicine (1966)

Case Studies1 July 1966Chronic Neutrophilic LeukemiaHARRY RUBIN, M.D.HARRY RUBIN, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-65-1-93 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptChronic neutrophilic leukemia is uncommon, and there is some question as to whether it should be considered a distinct disease entity. Few case reports exist in the literature. In one of the early descriptions of two cases (1), the authors concluded that this disorder was a variant of chronic myelogenous leukemia. The recent introduction of chromosomal analysis has been helpful in distinguishing chronic myelogenous leukemia within the group of myeloproliferative disorders, as have cytochemical techniques.We recently had the opportunity of studying a patient whose case closely resembled the previously described cases of chronic neutrophilic leukemia clinically and hematologically. 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CrossrefMedlineGoogle Scholar20. TAKASHILASZLO IJ: Döhle bodies and other granulocytic alterations during chemotherapy with cyclophosphamide. Ibid., p. 668. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Elmhurst, New YorkFrom the Departments of Medicine and Hematology, Mt. Sinai Hospital Services, City Hospital Center, Elmhurst, N. Y.This study was supported in part by grant CA-04457, U. S. Public Health Service, Washington, D. C., and grant 7-360, the American Cancer Society.Requests for reprints should be addressed to Harry Rubin, M.D., Mount Sinai Hospital Services, City Hospital Center at Elmhurst, 7901 Broadway, Elmhurst, N. Y. 11373. 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