tbuckley/cabot-search huggingface dataset:
THE OPERATIVE TREATMENT OF CHRONIC SUPPURATION OF THE FRONTAL SINUSWITH SPECIAL REFERENCE TO THE METHOD OF KILLIAN.
Authors: A. LOGAN TURNER
Journal: JAMA (1905)

The present aspect of surgical interference in chronic suppuration of the frontal sinus is, from several points of view, a subject of deep interest to all of us, and, along with the surgery of the other nasal sinuses, the history of its gradual development is a very engrossing one. In connection with the advances in this department Americans have taken a prominent place, in proof of which I need only mention the names of Holmes and Lothrop, Douglass and Mosher, Howard, Ingersoll, Pearce and Bryan. <h3>INDICATIONS FOR OPENING THE SINUS.</h3> Before discussing the lines of treatment which may be adopted it will be advisable to briefly consider the indications which should guide us in opening the sinus. Recently there has been a tendency, at any rate in some quarters, to follow more conservative methods, and perhaps to refrain from operative interference unless there is present some definite indication for so
Echocardiography-derived left ventricular end-systolic regional wall stress and matrix remodeling after experimental myocardial infarction
Authors: Luis E Rohde, Masanori Aikawa, George C Cheng, Galina Sukhova, Scott D Solomon, Peter Libby, Janice Pfeffer, Marc A Pfeffer, Richard T Lee
Journal: Journal of the American College of Cardiology (1999)
870-1 Chronic beta3-adrenergic receptor blockade causes regression of cardiac dysfunction in a rat model of progressive heart failure
Authors: Heng-Jie Cheng, Atsushi Morimoto, Hiroshi Hasegawa, Qing-Hua Han, David C Sane, William C Little, Che-Ping Cheng
Journal: Journal of the American College of Cardiology (2004)
A new approach to the diagnosis and study of <i> <scp>M</scp> alassezia </i> infections
Authors: P. Lecerf, R. Hay
Journal: British Journal of Dermatology (2014)

Journal Article A new approach to the diagnosis and study of Malassezia infections Get access P. Lecerf, P. Lecerf Department of Dermatology and Venereology University Hospitals Saint‐Pierre Brugmann and Children's University Hospital Queen Fabiola Université Libre de Bruxelles 4 Place Van Gehichten 1020 Brussels Belgium Search for other works by this author on: Oxford Academic Google Scholar R. Hay R. Hay Skin Infection Clinic King's College Hospital NHS Trust Denmark Hill London SE8 3RS U.K Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 170, Issue 2, 1 February 2014, Page 234, https://doi.org/10.1111/bjd.12711 Published: 01 February 2014
Randomized Trial of N-Butyl-2-Cyanoacrylate Compared with Injection of Hypertonic Saline-Epinephrine in the Endoscopic Treatment of Bleeding Peptic Ulcers
Authors: K. J. Lee, J. H. Kim, K. B. Hahm, S. W. Cho, Y. S. Park
Journal: Endoscopy (2000)

Theoretically, the injection of cyanoacrylate may be effective for peptic ulcer bleeding, but randomized clinical trials are rare. The aim of this study was to compare the efficacy of N-butyl-2-cyanoacrylate (Histoacryl) and hypertonic saline-epinephrine (HSE) in the endoscopic treatment of major peptic ulcer hemorrhage.A total of 126 patients with major peptic ulcer hemorrhage and active bleeding or a nonbleeding visible vessel were randomly allocated to endoscopic injection with HSE (63 patients; group 1) or to injection with Histoacryl (63 patients; group 2). The two groups were well matched for age, sex, initial hemoglobin values, ulcer size and location, and bleeding stigmata.Initial hemostasis was achieved in 58 cases (92.1%) in group 1 and in 60 cases (95.2%) in group 2 (P=0.717). Rebleeding rates were 16 of 58 in group 1 and seven of 60 in group 2 (P=0.051). There were no significant differences regarding the rates of permanent hemostasis (51 of 63 in group 1 vs. 57 of 63 in group 2, P=0.203), emergency surgery (seven of 58 in group 1 vs. three of 60 in group 2, P=0.200), or hospital mortality due to bleeding (0 in group 1 and 0 in group 2). With regard to the rebleeding rate, there was a significant difference between group 1 and group 2 in the subgroup with active arterial bleeding (11 of 26 in group 1 and four of 29 in group 2, P=0.039) but not in the subgroup with a nonbleeding visible vessel (five of 32 in group 1 and three of 31 in group 2, P=0.708). There were no statistically significant differences in hemostatic results between the two treatment groups in the subgroups with gastric ulcers or duodenal ulcers. Although no complications followed HSE therapy, arterial embolization with infarction occurred in two patients in the Histoacryl group, of whom one died.Compared with HSE injection, Histoacryl injection showed no statistically significant differences in hemostatic results, except for decreasing the rebleeding rate in the patients with active arterial bleeding. However, the use of Histoacryl to control peptic ulcer bleeding should be reserved as a last resort before surgery, because of possible embolic complication.
Accidents with Tenckhoff Catheters
Authors: THOMAS A. GOLPER
Journal: Annals of Internal Medicine (1981)

Letters and Corrections1 July 1981Accidents with Tenckhoff CathetersTHOMAS A. GOLPER, M.D., JEAN CARPENTER, R.N.THOMAS A. GOLPER, M.D.Search for more papers by this author, JEAN CARPENTER, R.N.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-95-1-121_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Many dialysis centers are initiating continuous ambulatory peritoneal dialysis with guidance from established programs. However, dialysis staff will inevitably face certain situations for which they have had little preparation. For this reason, we share our experience of two cases in which Tenckhoff catheters were accidently cut by scissors in the removal of tape. In both cases the catheters were salvaged and remain functional, and no episodes of peritonitis developed. A plan of management for such accidents is recommended.Case 1:During a dressing change, the patient's catheter was accidentally severed by bandage scissors about 3 cm above... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: THOMAS A. GOLPER, M.D.; JEAN CARPENTER, R.N.Affiliations: Veterans Administration Medical Center Portland, OR 97201 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byImaging of Peritoneal Dialysis Complications in ChildrenMechanical Complications of Peritoneal DialysisPeritoneal dialysis access and exit-site care including surgical aspectsRepair of Chronic Peritoneal Dialysis CatheterPeritoneal Catheter Placement and ManagementPeritoneal dialysis access and exit site careThe Permanent Tenckhoff CathetersTear of the Intraperitoneal Segment of the Tenckhoff Catheter as an Unusual Cause of Catheter MalfunctionThe Salvage of an Ultrashort Peritoneal Dialysis CatheterPeritoneal Catheters 1 July 1981Volume 95, Issue 1Page: 121-122KeywordsCathetersMedical dialysisPeritoneal dialysisPeritonitis ePublished: 1 December 2008 Issue Published: 1 July 1981 PDF downloadLoading ...
The risk of hemophagocytic lymphohistiocytosis in Hermansky-Pudlak syndrome type 2
Authors: Birthe Jessen, Sebastian F. N. Bode, Sandra Ammann, Subarna Chakravorty, Graham Davies, Jana Diestelhorst, Melissa Frei-Jones, William A. Gahl, Bernadette R. Gochuico, Matthias Griese, Gillian Griffiths, Gritta Janka, Christoph Klein, Tamara Kögl, Karin Kurnik, Kai Lehmberg, Andrea Maul-Pavicic, Andrew D. Mumford, David Pace, Nima Parvaneh, Nima Rezaei, Geneviève de Saint Basile, Annette Schmitt-Graeff, Klaus Schwarz, Gulsun T. Karasu, Barbara Zieger, Udo zur Stadt, Peter Aichele, Stephan Ehl
Journal: Blood (2013)
An isotope technique for measuring lactose absorption
Authors: P. R. Salmon, A. E. Read, C. F. McCarthy
Journal: Gut (1969)

Expired radiocarbon dioxide has been collected by a simple autotitration method following the ingestion of lactose-1-14C. With this method, which is suitable for clinical use, 12 subjects with alactasia have been readily separated from 24 normals, both groups being defined by strict criteria. This test, which may be used to measure the absorption of other sugars, is especially suitable for population surveys and may be used to investigate the distribution of disaccharidase deficiency. A further advantage is that false low readings resulting from rapid plasma clearance of absorbed sugar do not occur with this method although they may do so in up to one in three lactose tolerance tests, thereby overestimating the prevalence of alactasia.
Discordant morphologic features in bone marrow involvement by malignant lymphomas: Use of gene rearrangement patterns for diagnosis
Authors: Domnita Crisan, Joan C. Mattson
Journal: American Journal of Hematology (1995)

Abstract Discordant morphology between lymph node or extra‐nodal site and bone marrow (BM) involvement by non‐Hodgkin's malignant lymphoma (NHL) is a common occurrence, causing diagnostic difficulties. Additional diagnostic problems are posed by lymphoid aggregates commonly found in the BM of elderly patients, the age group with the highest incidence of lymphoma. Morphologic features are used to distinguish between benign and malignant lesions but no feature is diagnostic and exceptions are numerous. Immu‐nophenotyping is helpful for detecting B cell monoclonality, but it cannot detect T cell monoclonality. Unique B and T cell gene rearrangement patterns, the molecular “signature” of the lymphoma, can be used to detect monoclonal lymphoid populations. Finding the same rearrangement pattern in the BM as in the primary mass is proof of BM involvement by the same clone of malignant cells. We used B/T and Bcl‐2 gene rearrangements to help diagnose cases with discordant morphology between primary site and BM. One hundred and seventy‐five specimens, obtained from patients undergoing staging or restaging for NHL, were analyzed for B/T cell and Bcl‐2 gene rearrangements by multiple restriction endonuclease digestion and Southern hybridization with 32P labeled JH, JK, CTα, and Bcl‐2 probes. Forty‐two specimens (24%) from 24 patients showed discordant morphology: of 13 specimens with atypical lymphoid aggregates, only one had B cell gene rearrangement; of 15 specimens with morphologically benign lymphoid aggregates, one demonstrated B cell gene rearrangement; and of 14 specimens positive for NHL with different morphology than the lymph node, 13 were positive for B cell gene rearrangements. Molecular analysis can aid in the diagnosis of NHL, can establish a “baseline” for detection of recurrence, and is useful in monitoring therapy. These data suggest that it is also a tool for the pathologist in cases of discordant morphology between the primary tumor and BM, and should be strongly considered for each site. © 1995 Wiley‐Liss, Inc.
Sex differences in pain do exist: The role of biological and psychosocial factors
Authors: Gary B. Rollman
Journal: Behavioral and Brain Sciences (1997)

The evidence favoring sex differences in pain seems compelling ( berkley ). This commentary considers the role of such factors as anxiety, somatosensory amplification, and coping style in accounting for the differential response to pain in the laboratory and clinic, and emphasizes the need to base evaluation and treatment upon individual reports rather than gender-based stereotypes.
Prenatal origin of childhood acute myeloid leukemias harboring chromosomal rearrangements t(15;17) and inv(16)
Authors: Cliona M. McHale, Joseph L. Wiemels, Luoping Zhang, Xiaomei Ma, Patricia A. Buffler, James Feusner, Katherine Matthay, Gary Dahl, Martyn T. Smith
Journal: Blood (2003)
TCT-342 Impact of Diabetes Mellitus on Clinical Outcomes After Percutaneous Coronary Intervention With Drug-Eluting Stents for Unprotected Left Main Coronary Artery Disease
Authors: Giuseppe Ferrante, Marie-Claude Morice, Olivier Darremont, Didier Carrié, Yves Louvard, Jean-Louis Leymarie, Thierry Lefèvre, Philippe Garot
Journal: Journal of the American College of Cardiology (2012)
Blood pressure level, trend, and variability in Dunedin children. An 8-year study of a single birth cohort.
Authors: I M St George, S M Williams, P A Silva
Journal: Circulation (1990)

In a birth cohort of children in the Dunedin Multidisciplinary Health and Development Study in New Zealand, resting blood pressures were recorded biennially five times from age 7 to 15 years. Using previously described methods, we examined the level, trend, and variability of blood pressures in those children with at least three readings. The level, trend, and variability of height, weight, and body mass index were compared among six separate groups of children. Two groups were categorized on the basis of high systolic pressure levels, one with low variability and the other with high variability, which was thought to resemble adult labile hypertension. Two additional groups were categorized on the basis of increasing and decreasing blood pressure trends; the fifth group had consistently low blood pressures, and the sixth group consisted of the remaining children. There were significant differences among the groups for the level of all the physical measurements and for the trend of body mass index. No significant differences were found among the groups for gender or socioeconomic status. A parental history of high blood pressure, stroke, or heart attack was significantly more common in the first two groups.
Human rights group uncovers evidence of torture in Zimbabwe
Authors: A. Ferriman
Journal: BMJ (2002)

Evidence of severe torture in Zimbabwe, which is experiencing unrest in the weeks leading up to the country's presidential election in March, has been uncovered by a human rights organisation.

A delegation from Physicians for Human Rights, Denmark, which visited Zimbabwe last month, has reported finding “a series of persons who gave consistent and similar accounts of exposure to torture.” Members interviewed 14 people, of whom four were classified as torture victims, while another four gave accounts of ill treatment, one of whom was a sitting MP. The four torture victims had physical wounds consistent with the accounts of their treatment.

The group, which has published its report on a website sponsored by the Zimbabwe Democracy Trust, says it is “very concerned about the politicisation of health care and the harassment of human rights organisations offering treatment to victims of political violence.”

Dr Hans Draminsky Petersen, who led the delegation, told the BMJ , “In medical literature acute lesions that beyond any reasonable doubt indicate torture are very rarely described in a series of victims. We think the medical profession should be aware …
The sodium phantom
Authors: N. Graudal, G. Jurgens
Journal: BMJ (2011)

Cappuccio and colleagues’ analysis is unbalanced.1 Firstly, the mean sodium intake in population studies that found a lowering effect of sodium reduction on blood pressure was above 250 mmol. Therefore these results cannot be applied to most of the world’s populations, which have a mean intake of about 150 mmol.2 In a population with a normal …
AN ELECTRIC POLYGRAPH
Authors: Russell A. Waud
Journal: JAMA (1924)

The polygraph illustrated in Figure 1 was designed for the purpose of securing records of the arterial and venous pulses of greater amplitude than is possible with the types of polygraph previously employed.  The principle and mode of use of the instrument may be readily understood. In order to record the pulse in the radial artery, a small button ( Btn. , arterial recorder Fig. 1) on the end of a flat spring ( Spr. ) is applied over the artery ( Art. ); the tension of the spring may be varied by a device similar to that used in the Mackenzie 1 polygraph. The button ( Btn.′ ) fixed to the center of the diaphragm ( Dia.′ ) of the microphone ( Micr. ) rests on the spring ( Spr. ). In the circuit with the microphone is a battery ( Batt. ), a solenoid ( Sol. ) and a switch ( Sw. ). An armature ( Arm. ), swinging on a pivoted joint ( Jt. ), moves inside the solenoid. To the
Management of Patients With Sickle Cell Disease—Reply
Authors: Barbara P. Yawn, George Buchanan, Kathryn Hassell
Journal: JAMA (2015)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A Randomized, Double-Blind Placebo-Controlled Trial of Oral Creatine Monohydrate Augmentation for Enhanced Response to a Selective Serotonin Reuptake Inhibitor in Women With Major Depressive Disorder
Authors: In Kyoon Lyoo, Sujung Yoon, Tae-Suk Kim, Jaeuk Hwang, Jieun E. Kim, Wangyoun Won, Sujin Bae, Perry F. Renshaw
Journal: American Journal of Psychiatry (2012)

Antidepressants often take several weeks to work, but depressed women who took the antidepressant escitalopram plus 5 g/day of creatine monohydrate, a supplement that increases cellular energy, had earlier and greater symptom decreases than women who took escitalopram plus placebo. The authors found a difference by the second week of treatment, and the remission rate at 8 weeks was twice as high for the creatine group (52%) as for the placebo group (26%). Most side effects were attributed to escitalopram, not creatine, but serum creatinine was elevated in the treatment group.
A5.4 Prevalence of comorbidities in Paget’s disease of the bone a single centre report
Authors: C Deaconu, L Groşeanu, V Iorgoveanu, A Borangiu, D Opriş, I Săulescu, V Bojincă, M Negru, C Constantinescu, F Berghea, M Abobului, V Vlad, A Bălănescu, D Predeţeanu, R Ionescu
Journal: Annals of the Rheumatic Diseases (2015)

<h3>Background and objectives</h3> Paget disease (PD), also known as osteitis deformans, is characterised by single or multiple bone site alteration, including accelerated osteoclast-mediated resorption followed by increased low quality bone production. This process results in a disorganised, unsteady structure that may lead to bone deformity. This condition affects elderly adult population, with a slightly higher predominance in males and it is thought to have important genetic determinants. The association of comorbid conditions places a burden on the patients and imposes regular monitoring. The present study aims to evaluate associated medical conditions in patients suffering from PD. <h3>Methods</h3> We retrospectively identified 39 patients who were diagnosed with PD, based on clinical presentation, plain x-rays, scintigraphy or when necessary biopsy or bone turnover markers’ detection. For the study group we noted the presence of cardiovascular disorders – hypertension, ischaemic heart disease or rhythm abnormalities such as atrial fibrillation. Median body mass index (BMI) was calculated. Neurologic conditions namely hearing loss, Parkinson’s disease or cerebral stroke history were taken into account, as well as type 2 diabetes and prostate adenoma. Tobacco use was also assessed for the study group. Development of neoplasia was reviewed. Information was gathered from patients’ clinical charts over a period of one year. <h3>Results</h3> Out of the 39 patients included in the study lot, 64.1% were males and 35.9% of female gender (1.7:1 ratio) with a mean age of 65.67 years, who were mainly diagnosed on the basis of clinical and radiographic assessment (97.4%). 7.6% had positive family history of PD. The polyostotic form of PD encountered in 26 patients (66%) is prevalent over the monostotic pattern (13, 33.3%). The most common affected sites were the hip in 71.0% of patients, skull (44.7%), femoral bone (26.3%) and the lumbar spine (21.05%). 61.5% of patients were hypertensive while 28.2% associated ischaemic heart disease. 27.6% were priorly diagnosed with atrial fibrillation. Mean BMI value was calculated at 27.7 kg/m². 12.8% of patients were hypoacusic, 5.1% suffered from a cerebral stroke and the same percentage were diagnosed with Parkinson’s disease. 52% of males had prostate adenoma, 15.3% suffered from type 2 diabetes. 20.5% patients confirmed smoking status. Three patients developed neoplasia, namely squamous cell carcinoma, carcinoma of the breast and rectum with no correlation to disease duration. <h3>Conclusions</h3> Taking into consideration the difficulties that PD brings with it, associated comorbidities tend to diminish further the health and quality of life in these patients. Therefore a complete medical check-up is recommended on each follow up visit in order to improve their status.
Chromosome Studies in Familial Bowel Disease
Authors: W. H. Jacobs
Journal: JAMA (1965)

To the Editor:—  Occasionally, patients with ulcerative colitis, regional enteritis, or ileocolitis are observed who give a family history of inflammatory bowel disease. During the past year, we have studied six individuals, representing four families with inflammatory bowel disease.  Method: Chromosome studies were done by use of venous blood, according to the method of Moorhead et al, (Exp Cell Res20:613, 1960) with modifications. The chromosome number in all patients studied was 46, and the idiograms were normal. The accompanying Table describes the patients.  Comment: In a recent review dealing with familial ulcerative colitis, ileitis, and ileocolitis, Kirsner and Spencer (Ann Intern Med59:133-144, 1963) reported that 91 of 1,339 patients gave evidence of similar disease in relatives. It was rare for this disease to occur in more than two members of one family. Morris (Gut6:176, 1965) recently described a family in which eight members had
Evaluation of an Epidemiological Method: Rheumatoid Arthritis in Liberia
Authors: S. E. Malawista, L. R. Boies, S. W. Seides
Journal: Annals of the Rheumatic Diseases (1959)

All current studies of rheumatoid arthritis are hindered by the lack of a precise definition of the disease.Patients in an arthritis clinic are selected, so that those with mild or short-lived forms of the disease are probably rarely seen.Because of this, better definition of rheumatoid arthritis is being sought through epidemiological studies.Four approaches are available, either separately or in combination with one another.These include finding the prevalence rates of various factors in various populations:(1) History of arthritis, morning stiffness, or joint swelling (Kellgren, Lawrence, and