The Syndrome of Mitral Valve Prolapse: Problems and Perspectives
Authors: ANTHONY N. DEMARIA
Journal: Annals of Internal Medicine (1976)

Editorial Note1 October 1976The Syndrome of Mitral Valve Prolapse: Problems and PerspectivesANTHONY N. DEMARIA, M.D.ANTHONY N. DEMARIA, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-85-4-525 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe clinical manifestations of the mitral valve prolapse syndrome, which was long thought to be an obscure, infrequently encountered disorder, have become recognized with increasing frequency. Auscultatory abnormalities of mitral valve prolapse have been recognized, for example, in as many as 17% of asymptomatic female patients during screening examinations (1). Indeed, so frequently has auscultatory, echocardiographic, or cineangiographic evidence of the syndrome been found in asymptomatic persons without other evidence of heart disease, that clinical significance of the abnormalities thus detected has come into question. Nevertheless severe complications, presumably related to mitral valve prolapse, have been seen to occur in...References1. MARKIEWICZ W, STONER J, and LONDON E: Mitral valve prolapse in one hundred presumably healthy young females. Circulation 53:464-473, 1976 CrossrefMedlineGoogle Scholar2. GALLAVARDIN L: Pseudo-dédoublement du deuxieme bruit du coeur simulant le dédoublement mitral. Par bruit extracardiaque télésystolique surajouté. Lyon Med 121:409-422, 1913 Google Scholar3. CRILEY J, LEWIS K, and HUMPHRIES J: Prolapse of the mitral valve: clinical and cine-angiographic findings. Br Heart J 28:488-496, 1966 CrossrefMedlineGoogle Scholar4. DEMARIA A, KING J, and BOGREN H: The variable spectrum of echocardiographic manifestations of the mitral valve prolapse syndrome. Circulation 50:33-41, 1974 CrossrefMedlineGoogle Scholar5. KOCH F and HANCOCK E: Ten year follow-up of forty patients with the mid-systolic click/late systolic murmur syndrome. Am J Cardiol 37:149, 1976 CrossrefGoogle Scholar6. DEMARIA A, AMSTERDAM E, and VISMARA L: Arrhythmias in the mitral valve prolapse syndrome. Prevalence, nature and frequency. Ann Intern Med 84:656-660, 1976 LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: ANTHONY N. DEMARIA, M.D.Affiliations: Section of Cardiovascular Medicine Department of Internal Medicine School of Medicine University of California, Davis Davis, California PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byVentricular TachycardiaVentricular TachycardiaAnthony Nicholas Demaria, MD: A conversation with the editor**This series of interviews is underwritten by an unrestricted grant from Bristol-Myers Squibb.The Effect of Amyl Nitrite on the Mitral Valve Echocardiogram in Presumably Healthy Young AdultsAutonomic dysfunction in women with mitral valve prolapse syndrome. 1 October 1976Volume 85, Issue 4 Page: 525-526 Keywords Cardiovascular therapy Mitral valve prolapse ePublished: 1 December 2008 Issue Published: 1 October 1976 PDF downloadLoading ...