Angioimmunoblastic Lymphadenopathy, Immunoblastic Lymphoma, and False-Positive Seroconversion for Human Immunodeficiency Virus
Authors: DIANA NUNLEY
Journal: Annals of Internal Medicine (1987)

Letters and Corrections1 July 1987Angioimmunoblastic Lymphadenopathy, Immunoblastic Lymphoma, and False-Positive Seroconversion for Human Immunodeficiency VirusDIANA NUNLEY, M.D., TAMARA MUSGRAVE, M.D., STEVEN L. BERK, M.D., J. KELLY SMITH, M.D.DIANA NUNLEY, M.D.Search for more papers by this author, TAMARA MUSGRAVE, M.D.Search for more papers by this author, STEVEN L. BERK, M.D.Search for more papers by this author, J. KELLY SMITH, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-107-1-114_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Angioimmunoblastic lymphadenopathy, a rare, acquired disorder of unknown cause, shares certain clinical characteristics with the acquired immunodeficiency syndrome (AIDS). We report the case of a patient who had a clinicopathologic presentation of angioimmunoblastic lymphadenopathy with evolution to immunoblastic lymphoma who also had concomitant HIV false-positivity by enzyme-linked immunosorbent assay (ELISA) and Western blot testing. This finding contrasts those of two previous reports that described patients who had clinical and laboratory features suggestive of AIDS, and lymph node biopsy specimens that showed angioimmunoblastic lymphadenopathy (1). The finding is of further interest in light of the reports of B-cell...References1. BLUMENFELDBECKSTEAD WJ. Angioimmunoblastic lymphadenopathy with dysproteinemia in homosexual men with acquired immune deficiency syndrome. Arch Pathol Lab Med. 1983;107:567-9. MedlineGoogle Scholar2. LEVINEMEYERBEGANDY APM. Development of B-cell lymphoma in homosexual men: clinical and immunologic findings. Ann Intern Med. 1984;100:7-13. LinkGoogle Scholar3. ZIEGLERBECKSTEADVOLBERDING JJP. Non-Hodgkin's lymphoma in 90 homosexual men: relation to generalized lymphadenopathy and the acquired immunodeficiency syndrome. N Engl J Med. 1984;311:565-70. CrossrefMedlineGoogle Scholar4. BIBERFELDBREDBERG-RADENBOETTIGER GUB. Blood donor sera with false-positive Western blot reactions to human immunodeficiency virus [Letter]. Lancet. 1986;2:289. CrossrefMedlineGoogle Scholar5. KANKIBARINM'BOUP PFS. New human T-lymphotropic retrovirus related to simian T-lymphotrophic virus type III (STLV-III AGM). Science. 1986;232:238-43. CrossrefMedlineGoogle Scholar6. . Classification system for human T-lymphotrophic virus type III/lymphadenopathy-associated virus infections. Ann Intern Med. 1986;105:234-7. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: East Tennessee State University Quillen-Dishner College of Medicine Veterans Administration Medical Center Johnson City, TN PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByPositively false 1 July 1987Volume 107, Issue 1Page: 114-114KeywordsAIDSB cellsBiopsyClinical laboratoriesEnzyme linked immunosorbent assayHIVLymph nodesLymphomaResearch laboratoriesWestern blot Issue Published: 1 July 1987 PDF DownloadLoading ...