Potassium Sulphocyanate: A Note on Its Use for the Painful Crises in Sickle Cell Anemia
Authors: EDWARD G. TORRANCE
Journal: Annals of Internal Medicine (1932)

Article1 December 1932Potassium Sulphocyanate: A Note on Its Use for the Painful Crises in Sickle Cell AnemiaEDWARD G. TORRANCE, M.D., TRUMAN G. SCHNABEL, M.D., F.A.C.P.EDWARD G. TORRANCE, M.D.Search for more papers by this author, TRUMAN G. SCHNABEL, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-6-6-782 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSickle cell anemia is a disease of unknown etiology, its prognosis is uncertain and its treatment is entirely symptomatic. In its active stage it is noteworthy for its spontaneous remissions and relapses. Most observers have found that treatments thus far suggested do not materially alter the course of the disease. No therapeutic procedure seems to influence the degree of sickling in vivo. Blood transfusions bring about remissions with uncertain regularity, and are of temporary value when so induced. They do on occasions tide a severely anemic patient over a critical period.Liver diet has been tried by Sydenstricker1 and others...References1 SYDENSTRICKER VP: Sickle cell anemia, Med. Clin. No. Am., 1929, xii, 1451-1456. Google Scholar2 LEVY J: Sicklemia, ANN. INT. MED., 1929, iii, 47-54. LinkGoogle Scholar3 YATERMOLLARI WMM: Pathology of sickle cell anemia; report of a case with death during an "abdominal crisis", Jr. Am. Med. Assoc., 1931, xcvi, 1671-1675. CrossrefGoogle Scholar4 HAHNGILLESPIE EVEB: Sickle cell anemia; splenectomy, Arch. Int. Med., 1927, xxxix, 233-254. CrossrefGoogle Scholar5 HAHN EV: Sickle cell anemia, Med. Clin. No. Am., 1928, xi, 1171-1174. Google Scholar6 STEWART WB: Sickle cell anemia: report of a case with splenectomy, Am. Jr. Dis. Child., 1927, xxxiv, 72-80. CrossrefGoogle Scholar7 BELLKOTTEMITCHELLCOOLEYLEE AJRHAGTBP: Sickle cell anemia. Reports of two cases in young children in which splenectomy was performed, Am. Jr. Dis. Child., 1927, xxxiv, 923-933. CrossrefGoogle Scholar8 LANDONLYMAN JFAV: Sickle cell anemia with case report of splenectomy, Am. Jr. Med. Sci., 1929, clxxviii, 223-228. CrossrefGoogle Scholar9 HUCK JG: Sickle-cell anemia, Bull. Johns Hopkins Hosp., 1923, xxxiv, 335-344. Google Scholar10 SYDENSTRICKER VP: Sickle cell anemia, So. Med. Jr., 1924, xvii, 177-183. CrossrefGoogle Scholar11 JOSEPHS HW: Clinical aspects of sickle cell anemia, Bull. Johns Hopkins Hosp., 1928, xiii, 397-398. Google Scholar12 WOLLSTEINKREIDEL MKV: Sickle cell anemia, Am. Jr. Dis. Child., 1928, xxxvi, 998-1011. Google Scholar13 FRANKLINSCHWARTZ WLS: Sickle cell anemia, Jr. Lab. and Clin. Med., 1930, xv, 519-527. Google Scholar14 DOLGOPOLSTITT VBRH: Sickle cell phenomena in tuberculosis patients, Am. Rev. Tuberc., 1929, xix, 454-460. Abst. Jr. Am. Med. Assoc., 1929, xcii, 1795. Google Scholar15 HAHNGILLESPIE EVEB: Sickle cell anemia, Arch. Int. Med., 1927, xxxix, 233-254. CrossrefGoogle Scholar16 HAHN EV: Sickle cell (drepanocytic) anemia, Am. Jr. Med. Sci., 1928, clxxv, 206-217. CrossrefGoogle Scholar17 GRAHAMMCCARTY GSSH: Sickle cell anemia, Jr. Lab. and Clin. Med., 1927, xii, 536-547. Google Scholar18 BANCROFTRUTZLER WDJE: The colloid chemistry of the nervous systems. I. Sodium thiocyanate therapy, Jr. Phys. Chem., 1931, xxxv, (1), 1185-1211. CrossrefGoogle Scholar19 FINDLAY A: Physical chemistry for students of medicine, 1924, Longmans, Green & Co., New York, 195. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Philadelphia, Pa.From the Medical Section of the Philadelphia General Hospital.Presented at the meeting of the American Therapeutic Society, June 6, 1931. Received for publication, February 23, 1932. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byCyanide, Peroxide and Nitric Oxide Formation in Solutions of Hydroxyurea Causes Cellular Toxicity and May Contribute to Its Therapeutic PotencyEmergency department analgesia without narcotics for adults with acute sickle cell pain crisis: Case reports and review of crisis managementDesign and Testing of Antisickling TherapyUrea and sickle cell anemiaThe involvement of the nervous system in sickle-cell anemiaErkennung und Behandlung der AnämienDie Sichelzellenanämie 1 December 1932Volume 6, Issue 6Page: 782-788KeywordsAnemiaBlood transfusionDietEtiologyLiverPotassiumSickle cell disease Issue Published: 1 December 1932 PDF downloadLoading ...