GOLD SALTS FOR RHEUMATOID ARTHRITIS
Authors: PHILIP S. HENCH
Journal: Annals of Internal Medicine (1947)

Editorial1 April 1947GOLD SALTS FOR RHEUMATOID ARTHRITISPHILIP S. HENCHPHILIP S. HENCHSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-26-4-618 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptHaving returned to many professional and economic changes, the homecoming medical officer will have unfortunately found one condition relatively unchanged; namely, the frustrating problem of rheumatoid arthritis. He will also find still continuing and still unsettled, the prewar controversy over the use of gold salts for rheumatoid arthritis.Why are the opinions of internists and specialists concerning this treatment so diverse after twenty years of use? Gold salts were first employed for rheumatoid arthritis in Germany about 1927 by physicians who, impressed with results in tuberculosis, regarded rheumatoid arthritis as related to tuberculosis, an unproved untenable notion. First American reports...1 CECILKAMMERERDEPRUME RLWHFJ: Gold salts in the treatment of rheumatoid arthritis; a study of 245 cases, Ann. Int. Med., 1942, xvi, 811-827. Google Scholar2 COHENGOLDMANDUBBS AJAW: The treatment of rheumatoid arthritis with 417 courses of gold; an analysis of 259 cases, New England Jr. Med., 1945, ccxxxiii, 199-203. CrossrefGoogle Scholar3 GARDNER ER: The use of gold in rheumatoid arthritis, Med. Rec., 1941, cliii, 321-323. Google Scholar4 HARTUNG EF: The treatment of rheumatoid arthritis including gold salts therapy, Bull. New York Acad. Med., 1943, xix, 693-703. Google Scholar5 SUNDELIN F: Die Goldbehandlung der chronischen Arthritis unter besonderer Berücksichtigung der Komplikationen, Acta med. Scandinav., 1941 (Supp.), cxvii, 1-291. Google Scholar6 RAGANTYSON CTL: Chrysotherapy in rheumatoid arthritis; a three-year study of 142 cases, Am. Jr. Med., 1946, i, 252-256. CrossrefGoogle Scholar7 ELLMANLAWRENCETHOROLD PJSGP: Gold therapy in rheumatoid arthritis, Brit. Med. Jr., 1940, ii, 314-316. CrossrefGoogle Scholar8 FRASER TN: Gold treatment in rheumatoid arthritis, Ann. Rheumat. Dis., 1945, iv, 71-75. CrossrefGoogle Scholar9 SMYTHFREYBERG CJRH: Experiences with gold salts in the treatment of rheumatoid arthritis, Univ. Hosp. Bull., Ann Arbor, 1941, vii, 45-47. Google Scholar10 RAWLSGRUSKINRESSADWORZANSCHREIBER WGBJAAHJD: Analysis of results obtained with small doses of gold salts in the treatment of rheumatoid arthritis, Am. Jr. Med. Sci., 1944, ccvii, 528-533. CrossrefGoogle Scholar11 SHORT CL: Gold therapy of rheumatoid arthritis, Bull. New England Med. Center, 1942, iv, 31-34. Google Scholar12 SASHINSPANBOCKKLING DJDH: Gold therapy in rheumatoid arthritis, Jr. Bone and Joint Surg., 1939, n.s. xxi, 723-734. Google Scholar13 BOLANDHEADLEYHENCH EWNEPS: The treatment of agranulocytosis with penicillin, Jr. Am. Med. Assoc., 1946, cxxx, 556-559. CrossrefGoogle Scholar14 BOLANDHEADLEYHENCH EWNEPS: The treatment of agranulocytosis with penicillin: report of a case resulting from chrysotherapy for rheumatoid arthritis, Proc. Staff Meet., Mayo Clin., 1946, xxi, 197-206. Google Scholar15 SECHER K: Directions for the treatment of rheumatic joint diseases with sanocrysin and physical therapy, Copenhagen, Andr. Fred. Hst. & Son, 1946, 56 pp. Google Scholar16 COHENGOLDMANDUBBS AJAW: The treatment of acute gold and arsenic poisoning; use of BAL (2,3-dimercaptopropanol, British Anti-Lewisite), Jr. Am. Med. Assoc., 1947, cxxxiii, 749-752. CrossrefGoogle Scholar17 LOCKIENORCROSSGEORGE LMBMCW: Treatment of two reactions due to gold; response of thrombopenic purpura and granulocytopenia to BAL therapy, Jr. Am. Med. Assoc., 1947, cxxxiii, 754-755. CrossrefGoogle Scholar18 RAGANBOOTS CRH: The treatment of gold dermatitides; use of BAL (2,3-dimercaptopropanol), Jr. Am. Med. Assoc., 1947, cxxxiii, 752-754. CrossrefGoogle Scholar19 BLOCKKNAPP WDEL: Metabolism, toxicity and manner of action of gold compounds in the treatment of arthritis. VII. The effect of various gold compounds on the oxygen consumption of rat tissues, Jr. Pharmacol. and Exper. Therap., 1945, lxxxiii, 275-278. Google Scholar20 FREYBERG RH: Recent trends in the treatment of rheumatoid arthritis, Ohio State Med. Jr., 1942, xxxviii, 813-820. Google Scholar21 FREYBERGBLOCKWELLS RHWDGS: Gold therapy for rheumatoid arthritis; considerations based upon studies of the metabolism of gold, Clinics, 1942, i, 537-570. Google Scholar22 HARTUNGCOTTERGANNON EFJC: The excretion of gold following the administration of gold sodium thiomalate in rheumatoid arthritis, Jr. Lab. and Clin. Med., 1941, xxvi, 1750-1755. Google Scholar23 HENCH PS: The advantages of hepatic injury and jaundice in certain conditions, notably the rheumatic diseases, Med. Clin. North America, 1940, xxiv, 1209-1237. CrossrefGoogle Scholar24 CECIL RL: The problem of dosage in the administration of gold salts for rheumatoid arthritis, Med. Clin. North America, 1946, xxx, 545-552. CrossrefGoogle Scholar25 STEINBROCKER O: Therapeutic results in rheumatoid arthritis, Jr. Am. Med. Assoc., 1946, cxxxi, 189-193. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: PHILIP S. HENCH PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySpecial issue—before translational medicine: laboratory clinic relations lost in translation? Cortisone and the treatment of rheumatoid arthritis in Britain, 1950–1960Liver Function Tests in Rheumatoid ArthritisLiver Function Tests on Rheumatoid Arthritis Patients Showing Complication Associated with Gold TherapyLiver Function Tests in Rheumatoid ArthritisLiver Function Tests on Rheumatoid Arthritis Patients Showing Complication Associated with Gold TherapyGOLD-HORMONAL THERAPY IN RHEUMATOID ARTHRITIS*PAUL J. BILKA, M.D., MAX H. WEIL, M.D.RHEUMATISM AND ARTHRITIS REVIEW OF AMERICAN AND ENGLISH LITERATURE OF RECENT YEARS (TENTH RHEUMATISM REVIEW)* Part IIWILLIAM D. ROBINSON, M.D., F.A.C.P., EDWARD W. BOLAND, M.D., F.A.C.P., JOSEPH J. BUNIM, M.D., F.A.C.P., DARRELL C. CRAIN, M.D., F.A.C.P., EPHRAIM P. ENGLEMAN, M.D., F.A.C.P., WALLACE GRAHAM, M.D., F.R.C.P. (C), L. MAXWELL LOCKIE, M.D., F.A.C.P., MAX M. MONTGOMERY, M.D., F.A.C.P., CHARLES RAGAN, M.D., F.A.C.P., MARIAN W. ROPES, M.D., F.A.C.P., EDWARD F. ROSENBERG, M.D., F.A.C.P., CHARLEY J. SMYTH, M.D.Rheumatoid Arthritis, Sanocrysin Treatment and Prognosis1Experience With Cortisone in the Treatment of Rheumatoid ArthritisSEVERE POLYNEURITIS FOLLOWING GOLD THERAPY FOR RHEUMATOID ARTHRITIS*JOHN B. DOYLE, M.D., F.A.C.P., ESPEY F. CANNON, M.D. 1 April 1947Volume 26, Issue 4 Page: 618-624 Keywords Rheumatoid arthritis Salts ePublished: 1 December 2008 Issue Published: 1 April 1947 PDF downloadLoading ...