Antibody Response to Blastocystis hominis Infections
Authors: Zierdt Ch, Nagy B
Journal: Annals of Internal Medicine (1993)

Letters15 June 1993Antibody Response to Blastocystis hominis InfectionsCharles H. Zierdt, MDCharles H. Zierdt, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-118-12-199306150-00018 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:The pathogenicity of protozoan parasites of humans has been slow to be appreciated. Examples are Trypanosoma cruzi, Giardia lamblia, and Dientamoeba fragilis. Blastocystis hominis is a more recent example, despite a preponderance of evidence for pathogenicity [1-4].In our study, sera were obtained from 19 patients with symptomatic B. hominis infections. Two patients provided acute-phase sera and convalescent-phase sera. An indirect fluorescent antibody test (IFA) and an enzyme-linked immunosorbent assay (ELISA) were developed to search for antibodies against B. hominis. Both the IFA and ELISA techniques demonstrated specific IgG antibody against B. hominis (Table 1). The average ...References1. Kain KC, Noble MA, Freeman HJ, Barteluk RL. Epidemiology and clinical features associated with Blastocystis hominis infection. Diagn Microbiol Infect Dis. 1987; 8:235-44. Google Scholar2. Tsang TK, Levin BS, Morse SR. Terminal ileitis associated with Blastocystis hominis infection. Am J Gastroenterol. 1989; 84:798-9. Google Scholar3. Vannatta JB, Adamson D, Mullican K. Blastocystis hominis infection presenting as recurrent diarrhea. Ann Intern Med. 1985; 102:495-6. Google Scholar4. Zierdt CH. Blastocystis hominispast and future. Clin Microbiol Rev. 1991; 4:61-79. Google Scholar5. Spice WM, Ackers JP. The amoeba enigma. Parasitol Today. 1992; 8:402-6. Google Scholar Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byBlastocystis hominis: A Pathogenic ParasiteBlastocystis specific serum immunoglobulin in patients with irritable bowel syndrome (IBS) versus healthy controlsBlastocystis: To Treat or Not to Treat...The potential use of 29 kDa protein as a marker of pathogenicity and diagnosis of symptomatic infections with Blastocystis hominisKinetic analysis of antibody responses to Blastocystis hominis in sera and intestinal secretions of orally infected miceNew Insights on Classification, Identification, and Clinical Relevance of Blastocystis sppIs this recently characterized gastrointestinal pathogen responsible for rising rates of inflammatory bowel disease (IBD) and IBD associated autism in Europe and the United States in the 1990s?The role of Blastocystis hominis as a possible intestinal pathogen in travellers 15 June 1993Volume 118, Issue 12Page: 985-986KeywordsAntigensEnzyme linked immunosorbent assayGiardia lambliaGiardiasisMembrane proteinsPathogensProtozoan infectionsProtozoansRNATrypanosoma cruzi Issue Published: 15 June 1993 Copyright & PermissionsCopyright © 1993 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...