Acute Fatty Metamorphosis of the Liver
Authors: MARTIN GOLDBERG
Journal: Annals of Internal Medicine (1961)

Article1 September 1961Acute Fatty Metamorphosis of the LiverMARTIN GOLDBERG, M.D., CHARLES M. THOMPSON, M.D., F.A.C.P.MARTIN GOLDBERG, M.D.Search for more papers by this author, CHARLES M. THOMPSON, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-55-3-416 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptFatty metamorphosis of the liver is a common finding in autopsy or liver biopsy material obtained from patients with a history of severe alcoholism (1-4). In some instances, fatty liver is not associated with clinical manifestations of liver disease. In other cases, fatty metamorphosis may be of such severity as to be associated with acute signs and symptoms. In 1836 Addison (5) noted that most of the patients with fatty liver that he observed were addicted to alcohol. Most of the subsequent clinical reports of fatty liver have been intermingled with cases of Laennec's cirrhosis, and as a result a...References1. LEEVYZINKEWHITEGNASSI CMMRTJAM: Clinical observations on the fatty liver. Arch. Intern. Med. 92: 527, 1953. CrossrefGoogle Scholar2. SEIFEKESSLERLISA MBJJR: Clinical, functional and needle biopsy study of the liver in alcoholism. Arch. Intern. Med. 86: 658, 1950. CrossrefGoogle Scholar3. POPPERSZANTO HPB: Fatty liver with hepatic failure in alcoholics. J. Mount Sinai Hosp. N.Y. 24: 1121, 1957. MedlineGoogle Scholar4. CHALMERSMURPHYTAFT TCTLEB: Incidence, character and course of liver disease in chronic alcoholics as determined by needle biopsy. J. Clin. Invest. 27: 528, 1948. MedlineGoogle Scholar5. ADDISON T: Fatty degeneration of the liver. Guy. Hosp. Rep. 1: 476, 1836. Google Scholar6. MACLEANBEST DLCH: Choline and liver fat. Brit. J. Exp. Path. 5: 193, 1934. Google Scholar7. 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WEINSTEIN, M.D., ROY J. KORN, M.D., F.A.C.P., HYMAN J. ZIMMERMAN, M.D., F.A.C.P. 1 September 1961Volume 55, Issue 3Page: 416-432KeywordsAlcoholismAlcoholsCirrhosisFatty liverHospital medicineLiverLiver diseasesMalnutritionPhosphatasesSigns and symptoms ePublished: 1 December 2008 Issue Published: 1 September 1961 PDF downloadLoading ...