The Role of Acute Lower Respiratory Infection in Causing Pulmonary Insufficiency in Bronchiectasis
Authors: NEIL S. CHERNIACK
Journal: Annals of Internal Medicine (1967)

Article1 March 1967The Role of Acute Lower Respiratory Infection in Causing Pulmonary Insufficiency in BronchiectasisNEIL S. CHERNIACK, M.D., HARRY F. DOWLING, M.D., F.A.C.P., ROBERT W. CARTON, M.D., F.A.C.P., VERA E. MCBRYDE, M.D.NEIL S. CHERNIACK, M.D.Search for more papers by this author, HARRY F. DOWLING, M.D., F.A.C.P.Search for more papers by this author, ROBERT W. CARTON, M.D., F.A.C.P.Search for more papers by this author, VERA E. MCBRYDE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-66-3-489 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlthough effective antimicrobial treatment has reduced the prevalence of fulminating infections in patients with bronchiectasis, repeated and protracted episodes of acute lower respiratory infection continue to occur in certain individuals. Not only are these episodes a severe economic burden to the patient, but, more significantly, they may produce permanent lung damage. Since respiratory insufficiency, manifested functionally by bronchial obstruction and unequal ventilation-perfusion ratios, is commonly observed in patients with bronchiectasis, further deterioration of lung function would be expected to affect prognosis adversely (1, 2).We have analyzed the data on 63 patients with established bronchiectasis to determine whether repeated or...References1. CHERNIACKVOSTISAXTONLEPPERDOWLING NSKLGAMHHF: Pulmonary function tests in fifty patients with bronchiectasis. J. Lab. Clin. Med. 53: 693, 1959. MedlineGoogle Scholar2. CHERNIACKCARTON NSRW: Factors associated with respiratory insufficiency in bronchiectasis. Amer. J. Med. 41: 562, 1966. CrossrefMedlineGoogle Scholar3. LEPPERDOWLINGJACKSONCARTON MHHFGGRW: Natural history of placebotreated patients with chronic bronchial disease observed for 7 years. Antimicrob. 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Resp. Dis. 87: 487, 1963. CrossrefMedlineGoogle Scholar26. ALBERTARNETT RELC: Clearance of radioactive dust from the human lung. Arch. Industr. Health (Chicago) 12: 99, 1955. MedlineGoogle Scholar27. LANDERSDAVIDSON FPM: The etiology of bronchiectasis. Brit. J. Radiol. 11: 65, 1938. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Chicago, IllinoisFrom the Department of Medicine, University of Illinois, Chicago, Ill.This study was supported in part by research grant AI-01690, National Institutes of Health, Bethesda, Md.Dr. Cherniack is the recipient of career development award, 1 K3-HE-17, 792, National Heart Institute, and Dr. McBryde is a Public Health Service Fellow under training grant 5 TI AI 208, National Institute of Infectious Diseases, National Institutes of Health, Bethesda, Md.Requests for reprints should be addressed to Neil S. Cherniack, M.D., University of Illinois, Department of Medicine, 840 S. Wood St., Chicago, Ill. 60612. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByBronchiectasis and Chronic Suppurative Lung DiseaseBronchiectasis and Chronic Suppurative Lung DiseaseBronchiectasisBronchiectasis in Alaska Native children: Causes and clinical coursesRecurrent PneumoniaFamilial bronchiectasisBronchiektasie: Klinik 1 March 1967Volume 66, Issue 3Page: 489-497KeywordsBronchiectasisInfectious diseasesLower respiratory tract infectionsLungsResearch grantsRespiratory failureRespiratory system proceduresUpper respiratory tract infectionsVentilation perfusionVentilators Issue Published: 1 March 1967 PDF DownloadLoading ...