Pancreatitis and Cancer Chemotherapy
Authors: JAMES B. PUCKETT
Journal: Annals of Internal Medicine (1982)

Letters and Corrections1 September 1982Pancreatitis and Cancer ChemotherapyJAMES B. PUCKETT, M.D., BUTLER WILLIAM M., M.D., JAMES A. MCFARLAND, M.D.JAMES B. PUCKETT, M.D.Search for more papers by this author, BUTLER WILLIAM M., M.D.Search for more papers by this author, JAMES A. MCFARLAND, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-97-3-453_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Acute pancreatitis is an uncommon complication of cancer chemotherapy, and has been described in association with the use of L-asparaginase (1, 2), corticosteroids (3), and cytarabine (4). Only one patient previously has been reported with pancreatitis associated with combination chemotherapy (5). We report a patient who developed acute pancreatitis after therapy with cyclophosphamide, doxorubicin, and vincristine.A 24-year-old woman presented with a mediastinal immunoblastic lymphoma. The patient was treated with two cycles of cyclophosphamide, vincristine, and prednisone, but the disease progressed. Her regimen was modifed to cyclophosphamide (750 mg/m2 body surface area · d intravenously), doxorubicin (50...References1. LANDSUTOWFERNBACHLANEWILLIAMS VWDDT. Toxicity of L-asparaginase in children with advanced leukemia. Cancer. 1972;30:339-47. CrossrefMedlineGoogle Scholar2. WEETMANBAEHNER RR. Latent onset of clinical pancreatitis in children receiving L-asparaginase therapy. Cancer. 1974;34:780-5. CrossrefMedlineGoogle Scholar3. LEVITT M. Pancreatitis. In: WYNGAARDEN JB, SMITH LH, eds. Cecil Textbook of Medicine. 16th ed. Philadelphia: W. B. Saunders Co; 1982:733-9. Google Scholar4. ALTMANDINNDORFQUINN APJ. Acute pancreatitis in association with cytosine arabinoside therapy. Cancer. 1982;49:1384-6. CrossrefMedlineGoogle Scholar5. NEWMANELLIS CD. Pancreatitis during combination chemotherapy. Clin Oncol. 1979;5:83-4. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: University of South Carolina, School of Medicine Richland Memorial Hospital Columbia, SC 76565 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByAntineoplastic agents associated with the development of drug-induced pancreatitisThe Risk of Chronic Pancreatitis in Patients with Psoriasis: A Population-Based Cohort StudyDrug-Induced Acute Pancreatitis: An Evidence-Based ReviewThe Adverse Drug Reaction in the Gastrointestinal Tract: An OverviewSurgical Emergencies in the Cancer PatientManagement of PancreatitisAcute pancreatitis secondary to ifosfamideAcute pancreatitis after ifosfamide therapyAcute pancreatitis complicating therapy of Hodgkin disease: A case reportDrug-Induced Acute PancreatitisAcute Pancreatitis Associated with Chemotherapy for Germ Cell Tumors in Two PatientsMARK A. SOCINSKI, M.D., MARC B. GARNICK, M.D.4 Drug-induced pancreatitisHigh-dose cytosine arabinoside-associated pancreatitis 1 September 1982Volume 97, Issue 3Page: 453-453KeywordsAcute pancreatitisBody surface areaCancer chemotherapyCombination chemotherapyCyclophosphamideLymphomaPancreatitis Issue Published: 1 September 1982 PDF DownloadLoading ...