Significance of Morphologic Thyroiditis
Authors: KENNETH L. BECKER
Journal: Annals of Internal Medicine (1965)

Article1 June 1965Significance of Morphologic ThyroiditisKENNETH L. BECKER, M.D., JACK L. TITUS, M.D., PH.D., LEWIS B. WOOLNER, M.D., WILLIAM M. MCCONAHEY, M.D.KENNETH L. BECKER, M.D.Search for more papers by this author, JACK L. TITUS, M.D., PH.D.Search for more papers by this author, LEWIS B. WOOLNER, M.D.Search for more papers by this author, WILLIAM M. MCCONAHEY, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-62-6-1134 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSince the possible auto-immune nature of Hashimoto's thyroiditis was elucidated (1), association of this phenomenon with other diseases that also might be auto-immune in nature has been observed (2-7). In view of these apparent relationships, a retrospective study was undertaken of the clinical records of patients in whom morphologic evidence of thyroiditis or apparently related thyroid abnormalities had been observed at necropsy.MATERIAL AND METHODFrom the necropsy protocols of the Mayo Clinic for the years 1926 through 1960, those cases in which the morphologic diagnosis of Hashimoto's thyroiditis, chronic thyroiditis, lymphocytic thyroiditis, and atrophy or fibrosis of the thyroid...References1. ROITTDONIACHCAMPBELLHUDSON IMDPNRV: Auto-antibodies in Hashimoto's disease (lymphadenoid goitre). Lancet 2: 820, 1956. CrossrefGoogle Scholar2. SHARVILL D: Polymyositis and thyroiditis. Proc. Roy. Soc. Med. 51: 934, 1958. MedlineGoogle Scholar3. MCCONKEYCALLAGHAN BP: Thyroiditis and cirrhosis of liver. Lancet 1: 939, 1960. CrossrefGoogle Scholar4. BUCHANANCROOKSALEXANDERKOUTRASWAYNEGRAY WWJWDDAEJKG: Association of Hashimoto's thyroiditis and rheumatoid arthritis. Lancet 1: 245, 1961. CrossrefGoogle Scholar5. BECKERFERGUSONMCCONAHEY KLRHWM: The connective-tissue diseases and symptoms associated with Hashimoto's thyroiditis. New Eng. J. Med. 268: 277, 1963. CrossrefMedlineGoogle Scholar6. BECKERTITUSWOOLNERFERGUSON KLJLLBRH: Thyroiditis and rheumatoid arthritis. Proc. Mayo Clin. 38: 125, 1963. MedlineGoogle Scholar7. BECKERTITUSMCCONAHEYWOOLNER KLJLWMLB: Morphologic evidence of thyroiditis in myasthenia gravis. JAMA 187: 994, 1964. CrossrefMedlineGoogle Scholar8. WOOLNERMCCONAHEYBEAHRS LBWMOH: Struma lymphomatosa (Hashimoto's thyroiditis) and related thyroidal disorders. J. Clin. Endocr. 19: 53, 1959. CrossrefMedlineGoogle Scholar9. TUDHOPEWILSON GRGM: Anaemia in hypothyroidism. Quart. J. Med. 29: 513, 1960. MedlineGoogle Scholar10. TUDHOPEWILSON GRGM: Deficiency of vitamin B12 in hypothyroidism. Lancet 1: 703, 1962. CrossrefMedlineGoogle Scholar11. BLOODWORTHKIRKENDALLCARR JMWMTL: Addison's disease associated with thyroid insufficiency and atrophy (Schmidt syndrome). J. Clin. Endocr. 14: 540, 1954. CrossrefMedlineGoogle Scholar12. TUFFANELLIWINKELMANN DLRK: Scleroderma and its relationship to the "collagenoses": Dermatomyositis, lupus erythematosus, rheumatoid arthritis and Sjogren's syndrome. Amer. J. Med. Sci. 243: 133, 1962. MedlineGoogle Scholar13. KAPLANVAUGHAN MHJH: Reaction of rheumatoid sera with synovial tissue as revealed by fluorescent antibody studies (abstract). Arthritis Rheum. 2: 356, 1959. Google Scholar14. VAUGHAN JH: Hypersensitivity in the rheumatic diseases. Med. Clin. N. Amer. 45: 1133, 1961. CrossrefMedlineGoogle Scholar15. TAYLOR KB: Inhibition of intrinsic factor by pernicious anaemia sera. Lancet 2: 106, 1959. CrossrefMedlineGoogle Scholar16. SCHWARTZ M: Intrinsic factor antibody in serum from patients with pernicious anaemia. Lancet 2: 1263, 1960. CrossrefMedlineGoogle Scholar17. SIMPSON JA: Myasthenia gravis: a new hypothesis. Scot. Med. J. 5: 419, 1960. CrossrefGoogle Scholar18. MARSHALLWHITE AHRG: Experimental thymic lesions resembling those of myasthenia gravis. Lancet 1: 1030, 1961. CrossrefMedlineGoogle Scholar19. DAMESHEK W: Systemic lupus erythematosus: a complex auto-immune disorder? Ann. Intern. Med. 48: 707, 1958. LinkGoogle Scholar20. MEAD RK: Autoimmune Addison's disease: report of a possible case. New Eng. J. Med. 266: 583, 1962. CrossrefGoogle Scholar21. HUNGMIGEONPARROTT WCJRH: A possible autoimmune basis for Addison's disease in three siblings, one with idiopathic hypoparathyroidism, pernicious anemia and superficial moniliasis. New Eng. J. Med. 269: 658, 1963. CrossrefMedlineGoogle Scholar22. CHUDOMELJEŽKOVÁPÁVKOVÁKRATKOVÁ VZLE: Immunology of glomerulonephritis. Lancet 1: 968, 1961. CrossrefMedlineGoogle Scholar23. BURKHOLDER PM: Complement fixation in diseased tissues. I. Fixation of guinea pig complement in sections of kidney from humans with membranous glomerulonephritis and rats injected with anti-rat kidney serum. J. Exp. Med. 114: 605, 1961. CrossrefMedlineGoogle Scholar24. CURTISHECKAMANWHEELER ACJHAH: Study of the autoimmune reaction in dermatomyositis. JAMA 178: 571, 1961. CrossrefMedlineGoogle Scholar25. SCHWARTZDAMESHEK RW: The treatment of autoimmune hemolytic anemia with 6-mercaptopurine and thioguanine. Blood 19: 483, 1962. CrossrefMedlineGoogle Scholar26. BROBERGERPERLMANN OP: Demonstration of an epithelial antigen in colon by means of fluorescent antibodies from children with ulcerative colitis. J. Exp. Med. 115: 13, 1962. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Rochester, MinnesotaFrom the Mayo Clinic and Mayo Graduate School of Medicine, Rochester, Minn.Requests for reprints should be addressed to The Mayo Clinic, Rochester, Minn. 55902. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByHashimoto's Encephalopathy: Back to Square OneAutoimmune EncephalopathyHashimoto's EncephalopathyAutoimmune Diseases Co-occurring Within Individuals and Within FamiliesHashimoto encephalopathy: Etiologic considerationsLung bullae, bronchiectasis, and Hashimoto's disease associated with ulcerative colitis treated by colectomy.Polyradicular neuritis and Hashimoto's thyroiditisAdrenal function in autoimmune thyroiditisStruma Lymphomatosa (Hashimoto)Gastrointestinal Findings in Autoimmune Thyroiditis and Non-Goitrous Juvenile Hypothyroidism in ChildrenDie pathologische Morphologie der endokrinen RegulationsstörungenDie Strahlentherapie gutartiger Erkrankungen innersekretorischer DrüsenDie Strahlentherapie gutartiger Erkrankungen innersekretorischer DrüsenORGAN-SPECIFIC ANTIBODIES IN IDIOPATHIC PANHYPOPITUITARISM, PRIMARY THYROID AND ADRENAL INSUFFICIENCYREFERENCESFulminating diabetes with lymphocytic thyroiditis.THYROTOXICOSIS AND HASHIMOTO GOITRE IN A PAIR OF MONOZYGOTIC TWINS WITH SERUM LONG-ACTING THYROID STIMULATORCLINICAL AND PATHOLOGICAL SIGNIFICANCE OF ASYMPTOMATIC ATROPHIC THYROIDITISAddison's disease and hypothyroidism (Schmidt's syndrome)ABDOMINAL WOUND DISRUPTIONHASHIMOTO'S DISEASE 1 June 1965Volume 62, Issue 6Page: 1134-1138KeywordsFibrosisGlomerulonephritisGraduate medical educationHemolytic anemiaPernicious anemiaPolymyositisRetrospective studiesSclerodermaThyroidUlcerative colitis Issue Published: 1 June 1965 PDF DownloadLoading ...