Primary Addison's Disease in a Patient with the Acquired Immunodeficiency Syndrome
Authors: ELIZABETH E. GUENTHNER
Journal: Annals of Internal Medicine (1984)

Brief Reports1 June 1984Primary Addison's Disease in a Patient with the Acquired Immunodeficiency SyndromeELIZABETH E. GUENTHNER, M.D., STEVEN L. RABINOWE, M.D., ANTHONY VAN NIEL, M.D., ALLEN NAFTILAN, M.D., Ph.D., ROBERT G. DLUHY, M.D.ELIZABETH E. GUENTHNER, M.D., STEVEN L. RABINOWE, M.D., ANTHONY VAN NIEL, M.D., ALLEN NAFTILAN, M.D., Ph.D., ROBERT G. DLUHY, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-100-6-847 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptDisseminated infection involving the adrenal glands has been noted frequently at autopsy in patients with the acquired immunodeficiency syndrome (1, 2). However, results of adrenocorticotropin (ACTH) stimulation testing have been reported to be normal in some patients with the syndrome, and an association between the syndrome and primary Addison's disease has not been documented previously (3). We report the case of a patient who presented with primary Addison's disease followed 4 months later by the acquired immunodeficiency syndrome.A 32-year-old black man with a history of intravenous drug use presented in November 1982 with hypotension, hyponatremia (sodium, 127 meq/L; normal,...References1. MACHERREICHERTSTRAUS ACS. Death in the AIDS patient: role of cytomegalovirus [Letter]. N Engl J Med. 1983;309:1454. CrossrefMedlineGoogle Scholar2. TAPPERROTTERDAMLERNERAL'KHAFAJISEITZMAN MHCKP. Adrenal necrosis in the acquired immunodeficiency syndrome. Ann Intern Med. 1984;100:239-41. LinkGoogle Scholar3. KLEINMANNFRIEDLANDSURKS RDGM. Adrenocortical function in the acquired immunodeficiency syndrome [Letter]. Ann Intern Med. 1983;99:566. LinkGoogle Scholar4. ROSEWILLIAMSJAGGERLAULER LGPD. The 48-hour adrenocorticotrophin infusion test for adrenocortical insufficiency. Ann Intern Med. 1970;73:49-54. LinkGoogle Scholar5. BLIZZARDCHANLERKYLEHUNG RRMW. Adrenal antibodies in Addison's disease. Lancet. 1962;2:901-3. CrossrefMedlineGoogle Scholar6. REICHERTO'LEARYLEVENSSIMRELLMACHER CTDCA. Autopsy pathology in the acquired immune deficiency syndrome. Am J Pathol. 1983;112:357-82. MedlineGoogle Scholar7. ZAKOWSKIFLIGIELBERLINJOHNSON PSGL. Disseminated Mycobacterium avium-intracellulare infection in homosexual men dying of acquired immunodeficiency. JAMA. 1982;248:2980-2. CrossrefMedlineGoogle Scholar8. NEUFELDMACLARENBLIZZARD MNR. Two types of autoimmune Addison's disease associated with different polyglandular autoimmune (PGA) syndromes. Medicine (Baltimore). 1981;60:355-62. CrossrefMedlineGoogle Scholar9. RABINOWEJACKSONDLUHYWILLIAMS SRRG. Ia+ T lymphocytes in recently diagnosed idiopathic Addison's disease. Am J Med. 1984. (In press). CrossrefMedlineGoogle Scholar10. JACKSONMORRISHAYNESEISENBARTH RNBG. Increased circulating Ia-antigen-bearing T-cells in type I diabetes mellitus. N Engl J Med. 1982;306:785-8. 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Author, Article, and Disclosure InformationAffiliations: Brigham and Women's Hospital Boston, Massachusetts PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byHuman immune deficiency virus (HIV) infection and the hypothalamic pituitary adrenal axisThe effects of HIV-1 infection on endocrine organsAFatal Cytomegalovirus-Associated Adrenal Insufficiency in an AIDS Patient Receiving Corticosteroid TherapyAdrenal infectionsInfectious Causes of Adrenal InsufficiencyThe development of cytomegalovirus-induced adrenal failure in a patient with AIDS while receiving corticosteroid therapyNEUROENDOCRINE ABNORMALITIES ASSOCIATED WITH HIV INFECTIONThe HPA Axis and HIV InfectionRenal Complications of Intravenous Drug Abuse and Human Immunodeficiency Virus InfectionInsuffisance surrénale périphérique au cours du sidaA Unique Thyroid Hormone Response Element in the Human Immunodeficiency Virus Type 1 Long Terminal Repeat That Overlaps the Sp1 Binding SitesDisorders of Potassium Homeostasis: An Approach Based on PathophysiologyTrimethoprim-Induced Hyperkalemia in a Patient with AIDSThe adrenal gland in AIDSHormonal and immunological pattern in a patient with Acquired Immuno Deficiency Syndrome related complex and Cushing's syndromeEndocrine Complications of AIDS and Drug AddictionEndocrine Manifestations of Human Immunodeficiency Virus (HIV) InfectionAdrenocortical insufficiency with normal serum cortisol levels and hyporeninaemia in a patient with acquired immunodeficiency syndrome (AIDS)Oral melanotic macules in patients infected with human immunodeficiency virusGrowth and neuroendocrine dysfunction in children with acquired immunodeficiency syndromeAcquired Immunodeficiency Syndrome and the KidneyRenal complications of human immunodeficiency virus type 1Renal Complications of Human Immunodeficiency Virus-Type INew antifungal agentsAdrenal Insufficiency in the Intensive Care SettingThe Clinical Spectrum of Renal Disease Associated With Human Immunodeficiency VirusAnti-corticosteroid antibodies in AIDS patientsADRENOCORTICAL LESIONS AND HIV INFECTIONEndocrine disorders in men infected with human immunodeficiency virusMycobacterium avium-intracellulare and adrenal insufficiency in AIDSAddison's DiseasePathology of the pituitary gland in patients with the acquired immune deficiency syndrome (AIDS)Geometric Universality in Brain Allosteric Protein Dynamics:.Hypoglycemia in Hospitalized PatientsHyporeninemic hypoaldosteronism associated with acquired immune deficiency syndromeLack of response to suramin in patients with AIDS and AIDS-related complexThe Human Immunodeficiency Virus and the Adrenal MedullaCAROL D. WEISS, M.D.Murine cytomegalovirus adrenalitis in athymic nude miceSuramin and Function of the Adrenal CortexCY A. STEIN, M.D., Ph.D., WAYNE SAVILLE, B.S., ROBERT YARCHOAN, M.D., S. BRODER, M.D., EDWARD P. GELMANN, M.D.Adrenal Insufficiency as a Complication of the Acquired Immunodeficiency SyndromeLOREN WISSNER GREENE, M. D., WILLIAM COLE, M.D., JEFFREY B. GREENE, M.D., BRIAN LEVY, M.D., EDDIE LOUIE, M.D., BRUCE RAPHAEL, M.D., H. JOAN WAITKEVICZ, M.D., MANFRED BLUM, M.D.Ia-positive T lymphocytes in recently diagnosed idiopathic Addison's disease 1 June 1984Volume 100, Issue 6Page: 847-848KeywordsAIDSAdrenocorticotropic hormoneAutopsyBiopsyDrugsHyponatremiaHypotensionInfectious disease immunologyMetastasisSodium Issue Published: 1 June 1984 PDF downloadLoading ...