Heparin in Acute Partial Stable Stroke
Authors: E. A. LOELIGER
Journal: Annals of Internal Medicine (1987)

Letters and Corrections1 May 1987Heparin in Acute Partial Stable StrokeE. A. LOELIGER, M.D.E. A. LOELIGER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-106-5-781 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Duke and colleagues (1) present evidence that anticoagulation with heparin does not improve the short-term prognosis in patients with acute partial stable stroke. The authors gave no data, however, on the quality of treatment applied. We only know that heparin was given by intravenous infusion to maintain the activated partial thromboplastin time between 50 and 70 seconds. Such definition of treatment is grossly insufficient. Only with the knowledge of the brand of reagent used to effect changes in thromboplastin time, as well as knowledge of the methods used to read the time and of the percentage of...References1. DUKEBLOCHTURPIETREBILCOCKBAYER RRARN. Intravenous heparin for the prevention of stroke in acute partial stable stroke. Ann Intern Med. 1986;105:825-8. LinkGoogle Scholar2. BRANDTTRIPLETT JD. Laboratory monitoring of heparin: effect of reagents and instruments on the activated partial thromboplastin time. Am J Clin Pathol. 1981;76:530-7. MedlineGoogle Scholar3. LOELIGERBROEKMANS EA. Optimal therapeutic anticoagulation. Haemostasis. 1985;15:283-92. MedlineGoogle Scholar4. HULLDELMORECARTER RTC. Adjusted subcutaneous heparin versus warfarin sodium in the long-term treatment of venous thrombosis. N Engl J Med. 1982;306:189-94. CrossrefMedlineGoogle Scholar1. DUKETURPIEBLOCHTREBILCOCKBAYER RARRN. Intravenous heparin for the prevention of stroke progression in acute partial stable stroke: a randomized controlled trial. Ann Intern Med. 1986;105:825-8. LinkGoogle Scholar2. TURPIEDUKEBLOCHTREBILCOCKBAYER ARRRN. A randomized controlled trial of intravenous heparin for the prevention of stroke progression in acute partial thrombotic stroke [Abstract]. Circulation. 1985;72(suppl 111):536. MedlineGoogle Scholar3. DUKETURPIEBLOCHTREBILCOCKBAYER RARRN. A randomized controlled trial of heparin in acute partial thrombotic stroke [Abstract]. Stroke. 1986;17:133. Google Scholar1. DUKEBLOCHTURPIETREBILCOCKBAYER RRARN. Intravenous heparin for the prevention of stroke in acute partial stable stroke. Ann Intern Med. 1986;105:825-8. LinkGoogle Scholar2. TURPIEDUKEBLOCHTREBILCOCKBAYER ARRRN. A randomized controlled trial of intravenous heparin for the prevention of stroke progression in acute partial thrombotic stroke [Abstract]. Circulation. 1985;72(suppl 111):536. MedlineGoogle Scholar3. DUKETURPIEBLOCHTREBILCOCKBAYER RARRN. A randomized controlled trial of heparin in acute partial thrombotic stroke [Abstract]. Stroke. 1986;17:133. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByAnticoagulants for acute ischaemic strokeAnticoagulants for acute ischaemic strokeAnticoagulants for acute ischaemic strokeAnticoagulants for acute ischaemic stroke 1 May 1987Volume 106, Issue 5Page: 781-782KeywordsHeparinPartial thromboplastin timeStroke Issue Published: 1 May 1987 PDF DownloadLoading ...