Dysomia, Dysgeusia, and Nifedipine
Authors: JAMES L. LEVENSON
Journal: Annals of Internal Medicine (1985)

Letters and Corrections1 January 1985Dysomia, Dysgeusia, and NifedipineJAMES L. LEVENSON, M.D., KRISTINE KENNEDY, M.D.JAMES L. LEVENSON, M.D.Search for more papers by this author, KRISTINE KENNEDY, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-102-1-135_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Nifedipine is a calcium channel blocker widely used in the treatment of angina. Its adverse effects include flushing, dizziness, headache, pedal edema, upper gastrointestinal distress, weakness, paresthesias, and transient hypotension. Uncommon serious adverse effects may include congestive heart failure, increased angina, and cerebral ischemia (1). We have recently encountered distortion of taste (dysgeusia) and smell (dysosmia) in two patients taking nifedipine.A 71-year-old woman was hospitalized with unstable angina. She had been receiving nifedipine, 30 to 80 mg/d for 13 months, in addition to nitrates, digoxin, and furosemide. She also had a profound unexplained weight loss (27...References1. TERRY R. Nifedipine therapy in angina pectoris: Evaluation of safety and side effects. Am Heart J. 1982;104:681-9. CrossrefMedlineGoogle Scholar2. SCHIFFMAN S. Taste and smell in disease. N Engl J Med. 1983;308:1275-9, 1337-43. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Medical College of Virginia Hospital Richmond, VA 23298 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByDrug-Induced Taste DisordersAntiarrhythmic drug-induced smell and taste disturbancesDisrupted Odor PerceptionCalcium channel blockersSniffing out pharmacology: interactions of drugs with human olfactionChemosensory DisordersDrugs Used to Treat Hypertension, Heart Failure, and Angina PectorisDrug-Induced Taste DisordersDysgeusia with amlodipine ? a case reportCalcium channel blockersOlfactory Loss and Aging: An Ignored but Important RelationshipBasic and Clinical Aspects of OlfactionEffects of drugs on olfaction and tasteLoss of Taste, Smell, and Other Senses with AgeTaste and smell perception in the elderly: Effect of medications and diseaseMedication‐Induced Taste DisturbancesTroubles olfactifs d’origine médicamenteuse : analyse et revue de la littératureEffect of Medications on TasteDisturbances of Taste and Smell Induced by DrugsParoxysmal bilateral dysosmia treated by resection of the olfactory bulbsA study on the action of two calcium channel blockers (verapamil and flunarizine) upon an experimental model of tardive dyskinesia in ratsOlfaction in Aging and Medical DisordersDisorders in Taste and SmellProbleme bei der Behandlung mit KalziumantagonistenSide Effects — Overdosage — Contraindications — Drug InteractionsNifedipine-induced parotitis: A hypersensitivity reactionNebenwirkungen — Überdosierung (Vergiftung) — Kontraindikationen — ArzneimittelinteraktionenNIFEDIPINE-INDUCED PAROTITISNifedipine and Myoclonic DystoniaALICIA DE MEDINA, M.D., OLIVIA BIASINI, M.D., ALFONSO RIVERA, M.D., ALICIA SAMPERA, M.D.Dysomia, Dysgeusia, and DiltiazemJULIAN L. BERMAN, M.D. 1 January 1985Volume 102, Issue 1Page: 135-136KeywordsAnginaEdemaHeadachesHeart failureHypotensionNitratesSmellTasteUnstable anginaWeight loss Issue Published: 1 January 1985 PDF DownloadLoading ...