Postsplenectomy Sepsis with DF-2: Report of a Case with Isolation of the Organism from the Patient's Dog
Authors: WILLIAM J. MARTONE
Journal: Annals of Internal Medicine (1980)

Brief Reports1 September 1980Postsplenectomy Sepsis with DF-2: Report of a Case with Isolation of the Organism from the Patient's DogWILLIAM J. MARTONE, M.D., RICHARD W. ZUEHL, M.D., GEORGE E. MINSON, M.D., W. MICHAEL SCHELD, M.D.WILLIAM J. MARTONE, M.D.Search for more papers by this author, RICHARD W. ZUEHL, M.D.Search for more papers by this author, GEORGE E. MINSON, M.D.Search for more papers by this author, W. MICHAEL SCHELD, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-93-3-457 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptA fastidious gram-negative bacillus, operationally referred to as DF-2 at the Center for Disease Control, has recently been described as causing human bloodstream infections and meningitis (1-4). Butler and associates (2) found that 10 of 17 persons with DF-2 infection had been bitten by dogs, suggesting a zoonotic reservoir.The following case represents the first time to our knowledge that DF-2 has been isolated from the pet dog implicated in the transmission of infection.A 44-year-old man underwent a staging laparotomy with splenectomy in November 1977 for Hodgkin's disease. He subsequently received chemotherapy and radiotherapy. The patient remained well until...References1. BOBO R and NEWTON E. A previously undescribed gram-negative bacillus causing septicemia and meningitis. Am J Clin Pathol. 1976;65:564-9. CrossrefMedlineGoogle Scholar2. BUTLER T, WEAVER R, and RAMANI T. Unidentified gram-negative rod infection: a new disease of man. Ann Intern Med. 1977;86:1-5. LinkGoogle Scholar3. SCHLOSSBERG D. Septicemia caused by DF-2. J Clin Microbiol. 1979;9:297-8. CrossrefMedlineGoogle Scholar4. FINDLING J, POHLMANN G, and ROSE H. Fulminant gram-negative bacillemia (DF-2) following a dog bite in an asplenic woman. Am J Med. 1980;68:154-6. CrossrefMedlineGoogle Scholar5. BAILIE W, STOWE E, and SCHMITT A. Aerobic bacterial flora of oral and nasal fluids of canines with reference to bacteria associated with bites. J Clin Microbiol. 1978;7:223-31. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: WILLIAM J. MARTONE, M.D.; RICHARD W. ZUEHL, M.D.; GEORGE E. MINSON, M.D.; W. 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