THE PROBLEM OF LEPTOSPIROSIS
Authors: MILTON S. SACKS
Journal: Annals of Internal Medicine (1950)

Editorials1 August 1950THE PROBLEM OF LEPTOSPIROSISMILTON S. SACKS, M.D.MILTON S. SACKS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-33-2-481 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe prevalence of leptospiral infections is probably less fully appreciated by the medical profession of this country than in other parts of the world, particularly Europe. Yet competent investigators have repeatedly pointed out that conditions necessary for the occurrence of human leptospirosis exist in relative abundance in the United States.1, 2, 3The reasons for this discrepancy are many. Clinical presentation of this group of diseases is inadequate in that only one type, Weil's disease, in its more severe form is usually presented as the classical prototype of leptospiral infection. Many cases of leptospirosis which deviate from the typical clinical...1 AshePratt-ThomasKumpse WFARCW: Weil's disease: a complete review of American literature and an abstract of the world literature, Medicine 20: 145, 1941. CrossrefGoogle Scholar2 Bertucci EA: Leptospirosis, Am. J. M. Sc. 209: 86, 1945. CrossrefGoogle Scholar3 MolnerMeyerRaskin JGKFHA: Leptospiral infections, J. A. M. A. 136: 814, 1948. CrossrefMedlineGoogle Scholar4 AlstonJoshuaBorg-PetersenBroomStuartFieldEdwards JMJOCJCRDHIJT: Discussion on leptospirosis, Proc. Royal Soc. Med. 42: 707, 1949. CrossrefMedlineGoogle Scholar5 GochenourYagerWetmore WSRHPW: Antigenic similarity of bovine strains of leptospirae (United States) and Leptospira pomona , Proc. Soc. Exper. Biol. and Med. 74: 199, 1950. CrossrefMedlineGoogle Scholar6 Stavitsky AB: Characteristics of pathogenic spirochetes and spirochetoses with special reference to the mechanisms of host resistance, Bact. Rev. 12: 203, 1948. CrossrefMedlineGoogle Scholar7 LangworthyMoore HVAC: A study of Leptospira icterohemorrhagiae , J. Infect. Dis. 41: 70, 1927. CrossrefGoogle Scholar8 MeyerStewart-AndersonEddie KFBB: Epidemiology of leptospirosis, Am. J. Pub. Health 29: 347, 1939. CrossrefGoogle Scholar9 Larson CL: Leptospirosis in rats (R. norvegicus) in and about Washington, D. C.; evaluation of methods used for diagnosis, Pub. Health Rep. 58: 949, 1943. CrossrefGoogle Scholar10 Raven C: Canine leptospirosis in Pennsylvania, J. Infect. Dis. 69: 131, 1941. CrossrefGoogle Scholar11 Wylie JA: The relative importance of the renal and hepatic lesions in experimental Leptospirosis icterohemorrhagica , J. Path. and Bact. 58: 351, 1946. CrossrefMedlineGoogle Scholar12 StilesGoldsteinMcCann WWJDWS: Leptospiral nephritis, J. A. M. A. 131: 1271, 1946. CrossrefMedlineGoogle Scholar13 CargillBeeson WHPB: The value of spinal fluid examination as a diagnostic procedure in Weil's disease, Ann. Int. Med. 27: 396, 1947. LinkGoogle Scholar14 BuzzardWylie EMJA: Meningitis leptospirosa, Lancet 2: 417, 1947. CrossrefMedlineGoogle Scholar15 GardnerWylie ADJA: Laboratory diagnosis of Weil's disease, Lancet 1: 955, 1946. CrossrefMedlineGoogle Scholar16 Sheldon WH: Lesions of muscle in spirochetal jaundice (Weil's disease; spirochetosis icterohemorrhagica), Arch. Int. Med. 75: 119, 1945. CrossrefGoogle Scholar17 RandallWetmoreWarner RPWAR: Sonic-vibrated leptospirae as antigens in the complement-fixation test for the diagnosis of leptospirosis, J. Lab. and Clin. Med. 34: 1411, 1949. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: MILTON S. SACKS, M.D.Affiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAcute Liver Disease: Its Causes and Treatment 1 August 1950Volume 33, Issue 2Page: 481-486KeywordsInfectious diseasesLeptospirosis ePublished: 1 December 2008 Issue Published: 1 August 1950 PDF downloadLoading ...