Silent Sequences and the Safety of Blood Transfusions
Authors: THOMAS F. ZUCK
Journal: Annals of Internal Medicine (1988)

Editorials1 June 1988Silent Sequences and the Safety of Blood TransfusionsTHOMAS F. ZUCK, M.D.THOMAS F. ZUCK, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-108-6-895 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe emergence of the acquired immunodeficiency syndrome (AIDS) has fueled concerns of both physicians and their patients about the safety of blood transfusions. In the spring of 1983, after recognizing that AIDS could be transmitted by infusions of blood and blood products, people at increased risk for AIDS were asked not to donate blood or plasma. Testing donated blood and plasma for antibodies to the human immunodeficiency virus (HIV-1), the causative agent of AIDS, was initiated by blood banks in 1985. A method for donors to exclude their units from the blood supply in a confidential manner was instituted in...References1. WARDHOLMBERGALLEN JSJ. Transmission of human immunodeficiency virus (HIV) by blood transfusions screened as negative for HIV antibody. N Engl J Med. 1988;318:473-8. CrossrefMedlineGoogle Scholar2. ZUCK T. Transfusion-transmitted AIDS reassessed [Editorial]. N Engl J Med. 1988;318:511-2. CrossrefMedlineGoogle Scholar3. FARZADEGANPOLISWOLINSKY HMS. Loss of human immunodeficiency virus type 1 (HIV-1) antibodies with evidence of viral infection in asymptomatic homosexual men: a report from the Multicenter AIDS Cohort Study. Ann Intern Med. 1988;108:785-790. LinkGoogle Scholar4. KLEINNMAN S. Risk of AIDS transmission by anti-HIV negative blood [Abstract]. Abstracts, III International Conference on AIDS. Washington: 1987:107. Google Scholar5. BOVE J. Transfusion-associated hepatitis and AIDS: What is the risk? N Engl J Med. 1987;317:242-5. CrossrefMedlineGoogle Scholar6. WARDDEPPESAMSON JDS. Risk of immunodeficiency virus infection from blood donors who later developed the acquired immunodeficiency syndrome. Ann Intern Med. 1987;106:61-2. LinkGoogle Scholar7. PERKINSSAMSONGARNER HSJ. Risk of AIDS for recipients of blood components from donors who subsequently developed AIDS. Blood. 1987;70:1604-10. CrossrefMedlineGoogle Scholar8. RANKEVALLEKROHN ASM. Long latency precedes overt seroconversion in sexually transmitted human-immunodeficiency-virus infection. Lancet. 1987;2:589-93. CrossrefMedlineGoogle Scholar9. . AIDS: Knowledge and Attitudes. November, 1987. Rockville, Maryland: National Center for Health Statistics; 1988. DHHS publication no. (PHS) 88-1250. Google Scholar10. ZUCK T. Greetings—a final look back with comments about a policy of a zero-risk blood supply [Editorial]. Transfusion. 1987;27:447-8. CrossrefMedlineGoogle Scholar11. Can drugs reduce surgical blood loss? [Editorial]. Lancet. 1988;1:155-6. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: University of Cincinnati Medical Center Cincinnati, Ohio PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByFive myths about AIDS that have misdirected research and treatmentFive myths about AIDS that have misdirected research and treatmentSafety of Intravenous Immunoglobulin Preparations: A Prospective Multicenter Study to Exclude the Risk of Non-A, Non-B HepatitisAnti-HBc Testing Can Decrease the Residual Risk of Transfusion-Related HIV Transmission by More Than One ThirdSafety of the blood supply: Liability for transfusion‐associated AIDSPreventing Transfusion of Infectious Blood Negative for Human Immunodeficiency Virus Antibodies (Anti-HIV)Peter L. Page, MD 1 June 1988Volume 108, Issue 6Page: 895-897KeywordsAIDSAntibodiesBlood banksBlood plasmaBlood transfusionHIVHIV-1Hematologic testsSafety Issue Published: 1 June 1988 PDF DownloadLoading ...