Australia Antigen Ecology
Authors: LEWELLYS F. BARKER
Journal: Annals of Internal Medicine (1971)

Editorials1 July 1971Australia Antigen EcologyLEWELLYS F. BARKER, M.D., SAM T. GIBSON, M.D.LEWELLYS F. BARKER, M.D.Search for more papers by this author, SAM T. GIBSON, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-75-1-130 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSutnick and co-workers indicate in this issue of the ANNALS(p. 35) that working in a laboratory environment that is saturated with Australia antigen may be a hazardous occupation. Overwhelming evidence has accumulated in support of the hypothesis that the Australia antigen is intimately related to an agent causing hepatitis in man (1). This relationship was first described in the early work of Blumberg, Sutnick, London and their associates (2-4) and brought into clear focus by a number of studies concerned with the occurrence of the antigen in blood and blood products and in their recipients who developed posttransfusion hepatitis...References1. BLUMBERG B, LONDON W, and SUTNICK A: Australia antigen as a hepatitis virus: variation in host response. Amer J Med 48:1-8, 1970 CrossrefMedlineGoogle Scholar2. SUTNICK A, LONDON W, and GERSTLEY B: Anicteric hepatitis associated with Australia antigen: occurrence in patients with Down's syndrome. JAMA 205:670-674, 1968 CrossrefMedlineGoogle Scholar3. BLUMBERG B, SUTNICK A, and LONDON W: Hepatitis and leukemia: their relation to Australia antigen. Bull NY Acad Med 44:1566-1586, 1968 MedlineGoogle Scholar4. LONDON W, SUTNICK A, and BLUMBERG B: Australia antigen and acute viral hepatitis. Ann Intern Med 70:55-59, 1969 LinkGoogle Scholar5. PRINCE A: An antigen detected in the blood during the incubation period of serum hepatitis. Proc Nat Acad Sci USA 60:814-821, 1968 CrossrefMedlineGoogle Scholar6. OKOCHI K and MURAKAMI S: Observations on Australia antigen in Japanese. Vox Sang 15:374-385, 1968 CrossrefMedlineGoogle Scholar7. GOCKE D, GREENBERG H, and KAVEY N: Correlation of Australia antigen with posttransfusion hepatitis. JAMA 212: 877-879, 1970 CrossrefMedlineGoogle Scholar8. BARKER L, SHULMAN N, and MURRAY R: Transmission of serum hepatitis. JAMA 211:1509-1512, 1970 CrossrefMedlineGoogle Scholar9. MCCOLLUM R: Report of a conference. Serum antigens in viral hepatitis. J Infect Dis 120:641-643, 1969 CrossrefMedlineGoogle Scholar10. GILES J, MCCOLLUM R, and BERNDTSON L: Viral hepatitis: relationship of Australia/SH antigen to the Willowbrook MS-2 strain. New Eng J Med 281:119-122, 1969 CrossrefMedlineGoogle Scholar11. WALSH J, YALOW R, and BERSON S: Detection of Australia antigen and antibody by means of radioimmunoassay techniques. J Infect Dis 121:550-554, 1970 CrossrefMedlineGoogle Scholar12. VYAS G and SHULMAN N: Hemagglutination assay for antigen and antibody associated with viral hepatitis. Science 170: 332-333, 1970 CrossrefMedlineGoogle Scholar13. BARKER L and MURRAY R: Acquisition of persistent hepatitis associated antigen: clinical features in young adults. JAMA. In press Google Scholar14. CHALMERS T, ECKHART R, and REYNOLDS W: The treatment of acute infectious hepatitis. Controlled studies of the effects of diet, rest and physical reconditioning on the acute course of the disease and on the incidence of relapses and residual abnormalities. J Clin Invest 34:1163-1235, 1955 CrossrefMedlineGoogle Scholar15. REPSHER L and FREEBERN R: Effects of early and vigorous exercise on recovery from infectious hepatitis. New Eng J Med 281:1393-1396, 1969 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: LEWELLYS F. BARKER, M.D.; SAM T. GIBSON, M.D.Affiliations: Division of Biologics Standards National Institutes of Health Bethesda, Md. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byA Study of Q Fever in Central IsraelPersistence of Hepatitis Associated Antigen Within a Fixed PopulationAUSTRALIA ANTIGEN: A REVIEW WITH EMPHASIS ON ITS CLINICAL RELEVANCE IN AUSTRALIAThe anesthesiologist's legal responsibilities in blood transfusionsInfectious diseases: annual review of significant publications 1 July 1971Volume 75, Issue 1Page: 130-132KeywordsAntigensBloodEcologyHepatitisHepatitis AResearch laboratories ePublished: 1 December 2008 Issue Published: 1 July 1971 PDF downloadLoading ...