Muscle Infarction in Sickle Cell Anemia
Authors: Gregory J. Dennis, Richard M. Keating
Journal: Annals of Internal Medicine (1991)

Letters15 November 1991Muscle Infarction in Sickle Cell AnemiaGregory J. Dennis, MAJ, MC, USA, Richard M. Keating, LCDR, MC, USNGregory J. Dennis, MAJ, MC, USASearch for more papers by this author, Richard M. Keating, LCDR, MC, USNSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-115-10-831 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editors: In a recent issue of Annals, Valeriano-Marcet and Kerr (1) hypothesized that ischemia or infarction from irreversibly sickled cells explained the pain, swelling, and muscle contractures observed in some patients with sickle cell anemia. We report the case of a patient whose findings lend further support to this hypothesis.A 42-year-old black woman with previously documented sickle cell anemia was hospitalized for evaluation of recurrent fever, migratory musculoskeletal discomfort, and skin ulcerations of 2 weeks duration. One day before admission, she developed a painful, swollen left arm and an inability to straighten the arm at the elbow....References1. Valeriano-MarcetKerr JL. Myonecrosis and myofibrosis as complications of sickle cell anemia. Ann Intern Med. 1991;115:99-101. LinkGoogle Scholar2. FabryKaul MD. Sickle cell vaso-occlusion. Hematol Oncol Clin North Am. 1991;5:375-98. CrossrefMedlineGoogle Scholar3. Serjeant G. Leg ulceration in sickle cell anemia. Arch Intern Med. 1974;133:690-4. CrossrefMedlineGoogle Scholar4. LinKatonVon KorffBushLipscomb EWMTP. Frustrating patients: physician and patient perspectives among distressed high users of medical services. J Gen Intern Med. 1991;6:241-6. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: Gregory J. Dennis, MAJ, MC, USA; Richard M. Keating, LCDR, MC, USNAffiliations: Walter Reed Army Medical Center Rheumatology Service Washington, DC 20307 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe effect of vertebral artery characteristics on cervical discogenic pain and disabilityA rare case of compartment syndrome and myonecrosis in a patient with hemoglobin SC diseaseMyonecrosis in a Sickle Cell-Diseased Patient: A Case Report and Literature ReviewPeripheral Mechanisms of Ischemic MyalgiaMyonecrosis in Sickle Cell Anemia: Case StudyMyonecrosis in Sickle Cell Anemia—Overlooked and UnderdiagnosedBone Changes in Hematologic DiseasesMyonecrosis in Sickle Cell Anemia: Case Report and Review of the LiteratureNondiabetic thigh muscle infarction presenting as a possible primary antiphospholipid syndromeDiabetic thigh muscle infarction in association with antiphospholipid antibodiesSickle myonecrosis revisited 15 November 1991Volume 115, Issue 10Page: 831-832KeywordsAnemiaElbowFeversInfarctionInflammationIschemiaMuscle cellsMusclesMyalgiaUlcers ePublished: 1 December 2008 Issue Published: 15 November 1991 PDF downloadLoading ...