Fatal Arrhythmia After Pulse Methylprednisolone Therapy
Authors: RICHARD E. MOSES
Journal: Annals of Internal Medicine (1981)

Letters and Corrections1 December 1981Fatal Arrhythmia After Pulse Methylprednisolone TherapyRICHARD E. MOSES, D.O., ALICE MCCORMICK, D.O., WILLIAM NICKEY, D.O.RICHARD E. MOSES, D.O., ALICE MCCORMICK, D.O., WILLIAM NICKEY, D.O.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-95-6-781_3 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: In a recent letter Bocanegra and colleagues (1) reported two cases of cardiac arrest within 24 hours after pulse therapy with methylprednisolone. Although a possible relation was suggested, the writers could not show significant disturbances of cardiac rhythm in the three patients undergoing pulse therapy during cardiac monitoring. We wish to report a case of cardiac arrest within 24 hours after pulse therapy in a patient who was on cardiac monitoring during the terminal episode.A 72-year-old white woman was admitted to another institution because of shortness of breath, personality changes, pleuritic chest pain, and profound muscle...References1. BOCANEGRACASTAÑEDAESPINOZAVASEYGERMAIN TMLFB. Sudden death after methylprednisolone pulse therapy. Ann Intern Med. 1981;95:122. Letter. LinkGoogle Scholar2. CATHCARTIDELSONSCHEINBERGCOUSER EBMW. Beneficial effect of methylprednisolone "pulse" therapy in diffuse proliferative lupus nephritis. Lancet. 1976;1:163-6. CrossrefMedlineGoogle Scholar3. BOLTONCOUSER WW. Intravenous pulse methylprednisolone therapy of acute crescentic rapidly progressive glomerulonephritis. Am J Med. 1979;66:495-502. CrossrefMedlineGoogle Scholar4. KIMBERLYLOCKSHIN RM. Clinical efficacy of high dose intravenous methylprednisolone pulse therapy in systemic lupus erythematosis. Arthritis Rheum. 1979;22:629. Abstract. Google Scholar5. GARRETTPAULUS RH. Complications of intravenous methylprednisolone pulse therapy. Arthritis Rheum. 1980;23:677. Abstract. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. 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