Giant Duodenal Ulcer
Authors: STEVEN P. MISTILIS
Journal: Annals of Internal Medicine (1963)

Article1 August 1963Giant Duodenal UlcerSTEVEN P. MISTILIS, M.B., B.S., JEROME F. WIOT, M.D., STANLEY H. NEDELMAN, M.D.STEVEN P. MISTILIS, M.B., B.S.Search for more papers by this author, JEROME F. WIOT, M.D.Search for more papers by this author, STANLEY H. NEDELMAN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-59-2-155 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptMost peptic ulcers of the duodenum are 5 to 10 millimeters in diameter, and it is uncommon for ulcers to be greater than 1 centimeter (1). Since first described by Brdiczka in 1931 (2), only 34 cases have been reported in which the diameter of the ulcer exceeded 2 centimeters (1-14). These have been termed "giant" duodenal ulcers. It would appear that giant duodenal ulcer is an uncommon entity. However, we have collected 14 cases over a period of only 3 years.In view of the high mortality in undiagnosed cases it is important that this condition be recognized early....References1. ELKIN PW: Diagnostic problems in cases of large or giant duodenal ulcer. Radiology 37: 748, 1941. CrossrefGoogle Scholar2. BRDICZKA JG: Der grosse ulcus duodeni in röntgenbild. Fortschr. Roentgenstr. 44: 177, 1931. Google Scholar3. KUNTSSON F: Die nischendiagnostik bei sehr grossen duodenalgeschwüren. Acta Radiol. (Stockholm) 13: 34, 1932. Google Scholar4. FREEDMANGOEHRING EHD: Diagnostic errors in ulcerative lesions of the stomach and duodenum. Amer. J. Roentgen. 44: 45, 1940. Google Scholar5. KAHLSTROM SC: Giant ulcer of the duodenum. Med. Bull. Veterans Admin. 20: 451, 1944. Google Scholar6. EVASHWICK G: Giant benign duodenal ulcer—Report of a case. Ann. Surg., 133: 417, 1951. CrossrefMedlineGoogle Scholar7. HAMEL JF: Giant benign ulcerations of the duodenum. Canad. Med. Ass. J. 67: 665, 1952. MedlineGoogle Scholar8. RUBY RH: Giant benign ulcer of the duodenum. Mod. Med. 50: 357, 1953. Google Scholar9. HERRMAN SF: Giant duodenal ulcer. Western J. Surg. 65: 239, 1957. MedlineGoogle Scholar10. DAWSON J: Giant duodenal ulcer. Brit. J. Radiol. 31: 666, 1958. CrossrefMedlineGoogle Scholar11. PINKHELD RLBT: Giant ulcers or walled off perforations of the duodenum. New Eng. J. Med. 264: 541, 1961. CrossrefMedlineGoogle Scholar12. STAINTONGROWDON RMJH: Benign giant duodenal ulcer. Amer. Surg. 23: 1081, 1957. MedlineGoogle Scholar13. CRICK A: Giant duodenal ulcer. J. Coll. Radiol. Aust. 5: 75, 1961. CrossrefGoogle Scholar14. BULLOCKSNYDER WKEN: Benign giant duodenal ulcer. Gastroenterology 20: 330, 1952. CrossrefMedlineGoogle Scholar15. JONES FA: Hematemesis and melena. With special reference to causation and to the factors influencing the mortality from bleeding peptic ulcers. Gastroenterology 30: 166, 1956. CrossrefMedlineGoogle Scholar16. DRAGSTEDT LR: The pathogenesis of gastric and duodenal ulcers. Ann. N. Y. Acad. Sci. 99: 190, 1962. CrossrefMedlineGoogle Scholar17. JONESGUMMER FAJW: Clinical Gastroenterology, Charles C Thomas, Springfield, Illinois, 1960, p. 363. Google Scholar18. MARSHAK R: Personal communication, 1962. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Cincinnati, OhioFrom the Departments of Internal Medicine and Radiology, University of Cincinnati College of Medicine, and the Gastric Laboratory and Radiology Department of the Cincinnati General Hospital, Cincinnati, Ohio.Dr. Mistilis is a trainee in gastroenterology, under grant 2A-5120 (C4), National Institute of Arthritis and Metabolic Diseases, United States Public Health Service, Department of Health, Education, and Welfare, Washington, D. C.Requests for reprints should be addressed to Steven Mistilis, Gastric Laboratory, Cincinnati General Hospital, Cincinnati 29, Ohio. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByPeptic UlcersGiant duodenal ulcersGiant duodenal ulcerThe Geriatric Acute AbdomenGiant gastric and duodenal ulcers: A population-based study with a comparison to nongiant ulcersManagement of giant duodenal ulcerUltrasound demonstration of giant duodenal ulcerGiant duodenal ulcersGiant duodenal ulcerGiant duodenal ulcer: A dangerous variant of a common illnessGiant duodenal ulcersPerforation of Duodenal Ulcer during Barium MealABNORMAL COAGULATION AND TRAUMAENDOSCOPIC LIVER BIOPSYCARCINOMA OF THE COLON AND CHOLECYSTECTOMYRöntgenuntersuchung des MagensGiant duodenal ulcerResponse of giant duodenal ulcer to medical therapyClinical and radiographic features of giant duodenal ulcerPeptic Ulcer 1 August 1963Volume 59, Issue 2Page: 155-164KeywordsDiagnostic radiologyDuodenal ulcersDuodenumHospital medicineMedical servicesMetabolic disordersMortalityPeptic ulcersResearch laboratoriesUlcers Issue Published: 1 August 1963 PDF DownloadLoading ...