Transient Apical Ballooning Syndrome Precipitated by Dobutamine Stress Testing
Authors: Adam H. Skolnick
Journal: Annals of Internal Medicine (2009)

Letters7 April 2009Transient Apical Ballooning Syndrome Precipitated by Dobutamine Stress TestingAdam H. Skolnick, MD, Krista Michelin, MD, Ambika Nayar, MD, Daniel Fisher, MD, and Itzhak Kronzon, MDAdam H. Skolnick, MDFrom New York University School of Medicine, New York, NY 10016., Krista Michelin, MDFrom New York University School of Medicine, New York, NY 10016., Ambika Nayar, MDFrom New York University School of Medicine, New York, NY 10016., Daniel Fisher, MDFrom New York University School of Medicine, New York, NY 10016., and Itzhak Kronzon, MDFrom New York University School of Medicine, New York, NY 10016.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-150-7-200904070-00015 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Background: Transient apical ballooning syndrome, also known as takotsubo or stress cardiomyopathy, is incompletely understood. It is often precipitated by severe emotional stress; its clinical manifestations may mimic those of the acute coronary syndrome; and it is characterized by the absence of coronary artery disease and severe hypokinesis of the left ventricular apex on cardiac catheterization, both of which resolve within weeks. Because catecholamine surge may be a mechanism underlying the syndrome, dobutamine, a sympathomimetic medication commonly used in stress testing, may cause transient apical ballooning.Objective: To report a case of transient left ventricular apical ballooning syndrome precipitated by ...References1. Tsuchihashi K, Ueshima K, Uchida T, Oh-mura N, Kimura K, Owa M, et al; Angina Pectoris-Myocardial Infarction Investigations in Japan. Transient left ventricular apical ballooning without coronary artery stenosis: a novel heart syndrome mimicking acute myocardial infarction. Angina Pectoris-Myocardial Infarction Investigations in Japan. J Am Coll Cardiol. 2001;38:11-8. [PMID: 11451258] CrossrefMedlineGoogle Scholar2. Kawano H, Fujii H, Motoyama T, Kugiyama K, Ogawa H, Yasue H. Myocardial ischemia due to coronary artery spasm during dobutamine stress echocardiography. Am J Cardiol. 2000;85:26-30. [PMID: 11078231] CrossrefMedlineGoogle Scholar3. Cherian J, Kothari S, Angelis D, Atef A, Downey B, Kirkpatrick J. Atypical takotsubo cardiomyopathy: dobutamine-precipitated apical ballooning with left ventricular outflow tract obstruction. Tex Heart Inst J. 2008;35:73-5. [PMID: 18427659] MedlineGoogle Scholar4. Margey R, Diamond P, McCann H, Sugrue D. Dobutamine stress echo-induced apical ballooning (Takotsubo) syndrome. Eur J Echocardiogr. 2008. [PMID: 18945727] Google Scholar Author, Article, and Disclosure InformationAffiliations: From New York University School of Medicine, New York, NY 10016.Disclosures: None disclosed. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byClinical Manifestation of Stressful Cardiomyopathy (Takotsubo Syndrome) and the Problem of Differential Diagnosis with Acute Myocardial InfarctionAssociations among left ventricular systolic function, tachycardia, and cardiac preload in septic patientsDrug-Induced Takotsubo CardiomyopathyTakotsubo syndrome: aetiology, presentation and treatmentMiocardiopatía de takotsubo en la fase de recuperación de ecocardiografía de estrés con dobutaminaTakotsubo cardiomyopathy in aneurysmal subarachnoid hemorrhage: Institutional experience and literature reviewAdrenaline (Epinephrine)A New Insight Into Sudden Cardiac Death in Young PeopleTakotsubo Syndrome (or Apical Ballooning Syndrome) Secondary to ZolmitriptanReversible cardiogenic shock due to catecholamine-induced cardiomyopathy: a variant of takotsubo?Takotsubo CardiomyopathyTakotsubo cardiomyopathy occurring during the recovery period of dobutamine stress echocardiographyDobutamine-Precipitated Takotsubo Cardiomyopathy Mimicking Acute Myocardial InfarctionLeft ventricular outflow tract and mid-cavity obstruction may cause false-positive dobutamine stress echocardiogramsDrugs that affect autonomic functions or the extrapyramidal systemRecurrent, severe, and rapidly reversible apical ballooning syndrome in status asthmaticusTakotsubo Cardiomyopathy Induced by Dobutamine Infusion During Hypertensive Therapy for Symptomatic Vasospasm After Subarachnoid Hemorrhage -Case Report-Stress cardiomyopathy syndrome: A contemporary reviewLeft ventricular function and high-voltage electrical injury 7 April 2009Volume 150, Issue 7Page: 501-502KeywordsCatheterizationDyspneaEchocardiographyElectrocardiographyHeart diseasesIschemiaStable coronary artery diseaseTroponin ePublished: 7 April 2009 Issue Published: 7 April 2009 Copyright & PermissionsCopyright © 2009 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...