Castleman Disease-POEMS Syndrome Overlap
Authors: Romain K. Gherardi, Denis Malapert, Jean-Denis Degos
Journal: Annals of Internal Medicine (1991)

Letters15 March 1991Castleman Disease-POEMS Syndrome OverlapRomain K. Gherardi, MD, Denis Malapert, MD, Jean-Denis Degos, MDRomain K. Gherardi, MD, Denis Malapert, MD, Jean-Denis Degos, MDAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-114-6-520 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editors:Feigert and colleagues (1) have described an unusual association between multicentric angiofollicular lymph node hyperplasia (AFLNH) (multicentric Castleman disease) and a unique clinical syndrome of peripheral neuropathy, pseudotumor cerebri, IgA dysproteinemia, and thrombocytosis in four women. The authors assume that this symptom complex represents a distinct clinicopathologic entity taking a place among the various conditions in which AFLNH may be observed. They admit that there may be some relation between the complex and the POEMS (or Crow-Fukase) syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes) (2), but none of their patients showed the complete form of...References1. Feigert J, Sweet D, and Coleman M. Multicentric angiofollicular lymph node hyperplasia with peripheral neuropathy, pseudotumor cerebri, IgA dysproteinemia, and thrombocytosis in women. A distinct syndrome. Ann Intern Med. 1990;113:362-7. LinkGoogle Scholar2. Nakanishi T, Sobue I, and Toyokura Y. The Crow-Fukase syndrome: a study of 102 cases in Japan. Neurology. 1984;34:712-20. CrossrefMedlineGoogle Scholar3. Gherardi R, Baudrimont M, and Kujas M. Pathological findings in three non-Japanese patients with the POEMS syndrome. Virchows Arch (A). 1988;413:357-65. CrossrefGoogle Scholar4. Gherardi R, Zuber M, and Viard J. Les neuropathies dysglobulinémiques. Rev Neurol (Paris). 1988;144:391-408. MedlineGoogle Scholar1. Feigert J, Sweet D, and Coleman M. Multicentric angiofollicular lymph node hyperplasia with peripheral neuropathy, pseudotumor cerebri, IgA dysproteinemia, and thrombocytosis in women. A distinct syndrome. Ann Intern Med. 1990;113:362-7. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: Romain K. Gherardi, MD; Denis Malapert, MD; Jean-Denis Degos, MDAffiliations: Centre Hospitalier Universitaire Henri Mondor Créteil France PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byCastleman Disease with MDM2/CDK4 Protein Expression: a Potential Mimic of Inflammatory Variant of Liposarcoma with Significant ConsequencesQuantitative changes in blood cellsPOEMS syndrome: 2021 Update on diagnosis, risk‐stratification, and managementMultizentrische Castleman-Erkrankung in Kombination mit Polyserositis und POEMS-Syndrom – Fallbericht und ÜbersichtsbeitragSyndrome POEMS : diagnostic, prise en charge et traitementsPOEMS Syndrome: 2019 Update on diagnosis, risk‐stratification, and managementPOEMS SyndromePOEMS syndrome: 2017 Update on diagnosis, risk stratification, and managementPOEMS syndrome: Update on diagnosis, risk-stratification, and managementNeuropathy Associated with NeoplasiaQuantitative Changes in Blood CellsPapilledema as the Initial Presentation of Castleman DiseasePOEMS syndrome: 2014 Update on diagnosis, risk-stratification, and managementSíndrome de POEMSPOEMS syndrome: Update on diagnosis, risk-stratification, and managementPOEMS syndrome: 2011 update on diagnosis, risk-stratification, and managementPOEMS syndromePOEMS Syndrome (Osteosclerotic Myeloma)Le syndrome POEMS (ou syndrome de Crow-Fukase)POEMS syndrome: definitions and long-term outcomePoems Syndrome: A Case Report and DiscussionIncreased Expression of Vascular Endothelial Growth Factor (VEGF) in Castleman's Disease: Proposed Pathomechanism of Vascular Proliferation in the Affected Lymph NodeHuman Herpesvirus 8 Infection in Patients With POEMS Syndrome–Associated Multicentric Castleman's DiseaseHuman Herpesvirus 8 Infection in Patients With POEMS Syndrome–Associated Multicentric Castleman's DiseaseExpression of vascular endothelial growth factor in sera and lymph nodes of the plasma cell type of Castleman's diseaseLe POEMS syndromeSyndrome POEMS: rôles et intérêts de l'interleukine 6Neuropathy Associated with NeoplasiaPOEMS syndrome: A study of 25 cases and a review of the literatureCastleman Disease in Association With POEMSLetters to the editorCastleman's disease in poems syndrome with elevated interleukin-6 15 March 1991Volume 114, Issue 6 Page: 520-521 Keywords Lymph nodes Peripheral neuropathy Thrombocytosis ePublished: 1 December 2008 Issue Published: 15 March 1991 PDF downloadLoading ...