Bleomycin and Raynaud's Phenomenon
Authors: D. ADOUE
Journal: Annals of Internal Medicine (1984)

Letters and Corrections1 May 1984Bleomycin and Raynaud's PhenomenonD. ADOUE, P. ARLETD. ADOUESearch for more papers by this author, P. ARLETSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-100-5-770_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Grau and associates (1) have reported vinblastine-bleomycin therapy as a factor in the development of Raynaud's phenomenon associated with cancer chemotherapy. Neither bleomycin nor vinblastine alone had been reported to be associated with true Raynaud's phenomenon, although gangrene of the fingertips has been described (2). We wish to report a case in which bleomycin was the sole treatment.A 71-year-old woman with Kaposi's sarcoma developed Raynaud's phenomenon at the end of the second month of treatment with bleomycin alone (15 mg twice a week, 240 mg total). The clinical feature was a digital ischemia on cold exposure,...References1. GRAU J, GRAU M, MILLÁ A, ESTAPÉ J, and MULET M. Cancer chemotherapy and Raynaud's phenomenon [Letter]. Ann Intern Med. 1983;98:258. LinkGoogle Scholar2. COHEN I, MOSHER M, O'KEEFE E, KLAUS S, and DE CONTI R. Cutaneous toxicity of bleomycin therapy. Arch Dermatol. 1973;107:553-5. CrossrefMedlineGoogle Scholar3. DOUGLAS K. Photoactivity of bleomycin. Biomedicine. 1983;37:191-3. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: D. ADOUE; P. ARLETAffiliations: Hôpital Rangueil 31054 Toulouse France PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byManagement von Nebenwirkungen der Chemotherapie und deren LangzeitfolgenWhat Are the Long-Term Toxicities to Be Controlled and Treated?Complications associated with chemotherapy in testicular cancer managementLate complications of chemotherapy in testicular cancerScale for Chemotherapy-induced Long-term Neurotoxicity (SCIN): Psychometrics, Validation, and Findings in a Large Sample of Testicular Cancer SurvivorsVascular Toxicity of Antineoplastic AgentsComplications of surgery and chemotherapy for testicular cancerLong-Term Complications of Chemotherapy for Germ Cell TumoursLong-term chemotherapy-related cardiovascular morbidityComparative Tolerability of Chemotherapy Regimens for Germ Cell CancerCardiovascular toxicity with cancer chemotherapyChemotherapy in adult germ cell tumorsSecondary Raynaud's phenomenon and other late vascular complications following chemotherapy for testicular cancerRaynaud phenomenon in three patients with acquired immune deficiency syndrome-related kaposi sarcoma treated with bleomycinLong-term Follow-up of Cardiovascular Risk Factors in Patients Given Chemotherapy for Disseminated Nonseminomatous Testicular CancerJourik A. Gietema, MD, Dirk Th. Sleijfer, MD, Pax H. B. Willemse, MD, Heimen Schraffordt Koops, MD, Engbertha van Ittersum, MD, W. M. Monique Verschuren, MSc, Daan Kromhout, PhD, Willem J. Sluiter, PhD, Nanno H. Mulder, MD, Elisabeth G. E. de Vries, MDDrug Information Analysis Service; Octreotide Use in AIDSAcute Vascular Ischemic Events After Cisplatin-Based Combination Chemotherapy for Germ-Cell Tumors of the TestisDONALD C. DOLL, M.D., ALAN F. LIST, M.D., F. ANTHONY GRECO, M.D., JOHN D. HAINSWORTH, M.D., KENNETH R. HANDE, M.D., DAVID H. JOHNSON, M.D.Chemotherapy-associated Raynaud's phenomenon in a two-year-old girl 1 May 1984Volume 100, Issue 5Page: 770-770KeywordsCancer chemotherapyIschemiaKaposi sarcomaRaynaud syndrome ePublished: 1 December 2008 Issue Published: 1 May 1984 PDF downloadLoading ...