Liver Disease and Home Parenteral Nutrition
Authors: Karen C. McCowen
Journal: Annals of Internal Medicine (2000)

Letters19 December 2000Liver Disease and Home Parenteral NutritionKaren C. McCowen, MB, MRCPI, Peter A. Burke, MD, and Bruce R. Bistrian, MD, PhDKaren C. McCowen, MB, MRCPIBeth Israel Deaconess Medical Center; Boston, MA 02215 (McCowen, Burke, Bistrian)Search for more papers by this author, Peter A. Burke, MDBeth Israel Deaconess Medical Center; Boston, MA 02215 (McCowen, Burke, Bistrian)Search for more papers by this author, and Bruce R. Bistrian, MD, PhDBeth Israel Deaconess Medical Center; Boston, MA 02215 (McCowen, Burke, Bistrian)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-133-12-200012190-00022 SectionsAboutFull Text ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Cavicchi and colleagues reported on end-stage liver disease (ESLD) in patients with intestinal failure who were receiving long-term home parenteral nutrition (HPN) (1). One important finding was that patients with extremely short bowel had an increased risk for ESLD.We recently described 42 patients who had received a total of 283 patient-years of HPN (2). A relevant finding from our study—not examined by Cavicchi and coworkers—was a subgroup of young patients with extremely short bowel and normal serum albumin concentrations but no inflammatory disorders. These patients, who received HPN for a mean (±SD) of 13.6 ± 6.7 ...References1. Cavicchi M, Beau P, Crenn P, Degott C, Messing B. Prevalence of liver disease and contributing factors in patients receiving home parenteral nutrition for permanent intestinal failure. Ann Intern Med. 2000;132:525-32. LinkGoogle Scholar2. Chan S, McCowen KC, Bistrian BR, Thibault A, Keane-Ellison M, Forse RA, et al . Incidence, prognosis, and etiology of end-stage liver disease in patients receiving home total parenteral nutrition. Surgery. 1999;126:28-34. CrossrefMedlineGoogle Scholar3. McCowen KC, Ling PR, Bistrian BR. Arachidonic acid concentrations in patients with Crohn disease [Letter]. Am J Clin Nutr. 2000;71:1008. CrossrefMedlineGoogle Scholar4. Jeppesen PB, Hoy CE, Mortensen PB. Differences in essential fatty acid requirements by enteral and parenteral routes of administration in patients with fat malabsorption. Am J Clin Nutr. 1999;70:78-84. CrossrefMedlineGoogle Scholar5. Burke PA, Ling PR, Forse RA, Bistrian BR. Conditionally essential fatty acid deficiencies in end-stage liver disease. Nutrition. 1999;15:302-4. CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Karen C. McCowen, MB, MRCPI; Peter A. Burke, MD; Bruce R. Bistrian, MD, PhDAffiliations: Beth Israel Deaconess Medical Center; Boston, MA 02215 (McCowen, Burke, Bistrian) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoPrevalence of Liver Disease and Contributing Factors in Patients Receiving Home Parenteral Nutrition for Permanent Intestinal Failure Maryan Cavicchi , Philippe Beau , Pascal Crenn , Claude Degott , and Bernard Messing Metrics Cited byIntestinal failure-associated liver disease: Risks and regressionEffect of a Fish Oil–Containing Beverage on Changes in Plasma Lipid Fatty Acids in Patients With MalabsorptionAbnormal regulation of serum lipid fatty acid profiles in short gut rats fed parenteral nutrition with lipidParenteral nutrition associated liver diseasePrevention of parenteral nutrition-associated liver disease in childrenNutrition-Based Home Care 19 December 2000Volume 133, Issue 12Page: 1009-1010KeywordsAttentionEnd stage liver diseaseFatty acidsLipidsLiver diseasesNutrientsNutritionOilsSerum albuminSmall intestine ePublished: 19 December 2000 Issue Published: 19 December 2000 Copyright & PermissionsCopyright © 2000 by American College of Physicians. All Rights Reserved.Loading ...