Ocular Lyme Borreliosis Diagnosed by Polymerase Chain Reaction on Vitreous Fluid
Authors: Eileen Hilton
Journal: Annals of Internal Medicine (1996)

Letters1 September 1996Ocular Lyme Borreliosis Diagnosed by Polymerase Chain Reaction on Vitreous FluidEileen Hilton, MD, Candace Smith, PharmD, and Sunil Sood, MDEileen Hilton, MDLong Island Jewish Medical Center, New Hyde Park, NY 11042Search for more papers by this author, Candace Smith, PharmDLong Island Jewish Medical Center, New Hyde Park, NY 11042Search for more papers by this author, and Sunil Sood, MDLong Island Jewish Medical Center, New Hyde Park, NY 11042Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-125-5-199609010-00028 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:We describe a 26-year-old woman from Suffolk County, New York, who had pars planitis caused by Borrelia burgdorferi infection, as confirmed by polymerase chain reaction (PCR) on vitreous fluid. Results of serum Lyme enzyme-linked immunosorbent assay (ELISA), VDRL, and Mantoux tests were nonreactive. Serum IgG immunoblot for Lyme disease showed faint reactivity to the 34-, 41-, 60-, and 61-kDa proteins. Doxycycline (100 mg orally twice daily) was given as empirical treatment for Lyme disease. Visual acuity in the right eye improved from 20/400 to 20/200. After 2 months, however, the patient's vision in the left eye deteriorated ...References1. Bradley JF, Johnson RC, Goodman JL. The persistence of spirochetal nucleic acids in active Lyme arthritis. Ann Intern Med. 1994; 120:487-9. Google Scholar2. Steere AC, Duray PH, Kauffman DJ. Unilateral blindness caused by infection with the Lyme disease spirochete, Borrelia burgdorferi. Ann Intern Med. 1985; 103:382-4. Google Scholar3. Kauffmann JH, Wormser GP. Ocular Lyme disease: case report and review of the literature. Br J Ophthalmol. 1990; 74:325-7. Google Scholar4. Lesser RL. Ocular manifestations of Lyme disease. Am J Med. 1995; 98(Suppl 4A):60S-1S. Google Scholar5. Schubert HD, Greenebaum E, Neu HC. Cytologically proven seronegative Lyme choroiditis and vitritis. Retina. 1994; 14:39-43. Google Scholar Author, Article, and Disclosure InformationAuthors: Eileen Hilton, MD; Candace Smith, PharmD; Sunil Sood, MDAffiliations: Long Island Jewish Medical Center, New Hyde Park, NY 11042 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byBorrelia Ocular Infection: A Case Report and a Systematic Review of Published CasesSpirochetal DiseasesBorreliosis (Lyme Disease)Molecular Diagnosis of Ocular InfectionsSpirochetal DiseasesUvéites dues à la maladie de LymeSpirochetal Infections and the EyeSur quels éléments cliniques, épidémiologiques et biologiques faut-il évoquer la maladie de Lyme? Aspects dermatologiques et ophtalmologiques au cours de la maladie de LymeThieme Atlas of Anatomy: Head and NeuroanatomyPars PlanitisApplications of the Polymerase Chain Reaction to Diagnosis of Ophthalmic Disease 1 September 1996Volume 125, Issue 5Page: 424-425KeywordsDNAEnzyme linked immunosorbent assayInflammationLyme diseasePolymerase chain reactionSerum proteinsSouthern blotSpirochetesVisionVisual acuity ePublished: 15 August 2000 Issue Published: 1 September 1996 Copyright & PermissionsCopyright © 1996 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...