Sleep Well and Stay Slim: Dream or Reality?
Authors: Shahrad Taheri, Emmanuel Mignot
Journal: Annals of Internal Medicine (2010)

Editorials5 October 2010Sleep Well and Stay Slim: Dream or Reality?Shahrad Taheri, MBBS, PhD and Emmanuel Mignot, MD, PhDShahrad Taheri, MBBS, PhDFrom University of Birmingham, Birmingham Collaboration for Leadership in Health Research and Care, and Heartlands Biomedical Research Centre, Birmingham B9 5SS, United Kingdom; and Stanford Sleep Medicine Center, Redwood City, CA 94063.Search for more papers by this author and Emmanuel Mignot, MD, PhDFrom University of Birmingham, Birmingham Collaboration for Leadership in Health Research and Care, and Heartlands Biomedical Research Centre, Birmingham B9 5SS, United Kingdom; and Stanford Sleep Medicine Center, Redwood City, CA 94063.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-153-7-201010050-00012 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail The prevalence of obesity is increasing worldwide, with serious consequences for affected individuals, health care systems, and society. Because of the lack of effective interventions for obesity prevention, obesity is likely to continue to be a major public health challenge for many years to come. Once obesity occurs, the available medical treatment options include only a diminishing array of drugs and bariatric surgery. The key to successful weight loss and its maintenance is adoption of a healthy lifestyle through altering food selection, reducing calorie intake, and increasing physical activity (1). Unfortunately, many obese individuals do not successfully modify their lifestyle, ...References1. Wing RR, Phelan S. Long-term weight loss maintenance. Am J Clin Nutr. 2005;82:222S-225S. [PMID: 16002825] CrossrefMedlineGoogle Scholar2. Taheri S. Sleep and metabolism: bringing pieces of the jigsaw together [Editorial]. Sleep Med Rev. 2007;11:159-62. [PMID: 17517354] CrossrefMedlineGoogle Scholar3. Cizza G, Skarulis M, Mignot E. A link between short sleep and obesity: building the evidence for causation [Editorial]. 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Sleep. 2002;25:68-87. [PMID: 11833857] CrossrefMedlineGoogle Scholar9. Spiegel K, Tasali E, Penev P, Van Cauter E. Brief communication: sleep curtailment in healthy young men is associated with decreased leptin levels, elevated ghrelin levels, and increased hunger and appetite. Ann Intern Med. 2004;141:846-50. [PMID: 15583226] LinkGoogle Scholar10. Nedeltcheva AV, Kilkus JM, Imperial J, Kasza K, Schoeller DA, Penev PD. Sleep curtailment is accompanied by increased intake of calories from snacks. Am J Clin Nutr. 2009;89:126-33. [PMID: 19056602] CrossrefMedlineGoogle Scholar11. Nedeltcheva AV, Kilkus JM, Imperial J, Schoeller DA, Penev PD. Insufficient sleep undermines dietary efforts to reduce adiposity. Ann Intern Med. 2010;153:435-41. LinkGoogle Scholar12. Spiegel K, Leproult R, L'hermite-Balériaux M, Copinschi G, Penev PD, Van Cauter E. Leptin levels are dependent on sleep duration: relationships with sympathovagal balance, carbohydrate regulation, cortisol, and thyrotropin. 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[PMID: 20423926] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From University of Birmingham, Birmingham Collaboration for Leadership in Health Research and Care, and Heartlands Biomedical Research Centre, Birmingham B9 5SS, United Kingdom; and Stanford Sleep Medicine Center, Redwood City, CA 94063.Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M10-2045.Corresponding Author: Shahrad Taheri, MBBS, PhD, Heartlands Biomedical Research Centre, MIDRU Building, Heartlands Hospital, Bordesley Green East, Birmingham B9 5SS, United Kingdom; e-mail, S.[email protected]ac.uk.Current Author Addresses: Dr. Taheri: Heartlands Biomedical Research Centre, MIDRU Building, Heartlands Hospital, Bordesley Green East, Birmingham B9 5SS, United Kingdom.Dr. Mignot: Stanford Sleep Medicine Center, 450 Broadway Street, Pavilion B, 2nd Floor, Redwood City, CA 94063. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoInsufficient Sleep Undermines Dietary Efforts to Reduce Adiposity Arlet V. Nedeltcheva , Jennifer M. Kilkus , Jacqueline Imperial , Dale A. Schoeller , and Plamen D. Penev Metrics Cited byClinical and metabolic characteristics of the Diabetes Intervention Accentuating Diet and Enhancing Metabolism (DIADEM-I) randomised clinical trial cohortComparison of Sleep patterns in Menopausal and Non-menopausal Women: Results of the First Phase of Shahedieh Cohort StudySleep Optimization and Diabetes Control: A Review of the LiteratureObesity and Type 2 DiabetesEffects of Experimental Sleep Restriction on Caloric Intake and Activity Energy ExpenditureAssociation between weight gain, obesity, and sleep duration: a large-scale 3-year cohort studyOlanzapine Causes a Leptin-Dependent Increase in Acetylcholine Release in Mouse Prefrontal Cortex 5 October 2010Volume 153, Issue 7Page: 475-476KeywordsBioenergeticsBody weightExerciseGhrelinLeptinObesitySleepSleep deprivationWeight gainWeight loss ePublished: 5 October 2010 Issue Published: 5 October 2010 Copyright & PermissionsCopyright © 2010 by American College of Physicians. 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