Scleroderma of the Esophagus
Authors: WILLIAM L. TREACY
Journal: Annals of Internal Medicine (1963)

Article1 September 1963Scleroderma of the EsophagusA Correlation of Histologic and Physiologic FindingsWILLIAM L. TREACY, M.D., ARCHIE H. BAGGENSTOSS, M.D., CHARLES H. SLOCUMB, M.D., CHARLES F. CODE, M.D.WILLIAM L. TREACY, M.D., ARCHIE H. BAGGENSTOSS, M.D., CHARLES H. SLOCUMB, M.D., CHARLES F. CODE, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-59-3-351 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptEhrman (1) in 1903 was the first to describe progressive dysphagia resulting from involvement of the esophagus in a case of scleroderma. In 1943, Lindsay, Templeton, and Rothman (2) described the roentgenographic changes of atony and apparent spasm of the cardia in scleroderma. Since then, hypomotility of the esophagus has become established as an early and quite characteristic change in scleroderma (3, 4).This study was undertaken to explore the sclerodermatous process in the esophagus by correlating physiologic and pathologic changes. The investigation is divided into 3 parts: [1] a determination of the pathologic changes present in the esophagus in...References1. EHRMAN S: Quoted by LEINWAND, I., DURYEE, A. W., RICHTER, M. N.: Scleroderma (based on a study of over 150 cases). Ann. Intern. Med. 41: 1003, 1954. LinkGoogle Scholar2. LINDSAYTEMPLETONROTHMAN JRFES: Lesions of the esophagus in generalized progressive scleroderma. JAMA 123: 745, 1943. CrossrefGoogle Scholar3. CREAMERANDERSENCODE BHACF: Esophageal motility in patients with scleroderma and related diseases. Gastroenterologia 86: 763, 1956. CrossrefMedlineGoogle Scholar4. CODESCHLEGEL CFJF: The pressure profile of the gastroesophageal sphincter in man: an improved method of detection. Proc. Mayo Clin. 33: 406, 1958. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Rochester, MinnesotaThis investigation was supported in part by research grant A-2015 from the National Institute of Arthritis and Metabolic Diseases, Bethesda, Maryland.Requests for reprints should be addressed to: Mayo Clinic, Rochester, Minnesota. 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Esophageal involvementControl of Malabsorption in Scleroderma*Esophageal motor abnormalities in scleroderma and related diseasesThymoma associated with megaesophagusAnnouncementEntero-arthropathy: The Coexistence of Articular and Gastrointestinal Manifestations in Systemic DiseaseThe EsophagusPeroral Duodenal Biopsy in Progressive Systemic SclerosisCollagen disease primarily affecting the gastrointestinal tractEsophageal motor functionAperistalsis of the Esophagus in Patients with Connective-Tissue Disorders and Raynaud's PhenomenonDiseases of the esophagus 1 September 1963Volume 59, Issue 3Page: 351-356KeywordsArthritisCardiaDysphagiaEsophagusMetabolic disordersResearch grantsScleroderma Issue Published: 1 September 1963 PDF downloadLoading ...