Isolation of Pittsburgh Pneumonia Agent from Nebulizers Used in Respiratory Therapy
Authors: G. W. GORMAN
Journal: Annals of Internal Medicine (1980)

Brief Reports1 October 1980Isolation of Pittsburgh Pneumonia Agent from Nebulizers Used in Respiratory TherapyG. W. GORMAN, B.S., V.L. YU, M.D., A. BROWN, M.D., J.A. HALL, M.S., W.T. MARTIN, M.S., W.F. BIBB, M.S., G.K. MORRIS, Ph.D., M.H. MAGNUSSEN, M.P.H., D.W. FRASER, M.D.G. W. GORMAN, B.S., V.L. YU, M.D., A. BROWN, M.D., J.A. HALL, M.S., W.T. MARTIN, M.S., W.F. BIBB, M.S., G.K. MORRIS, Ph.D., M.H. MAGNUSSEN, M.P.H., D.W. FRASER, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-93-4-572 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptPittsburgh pneumonia agent was recently reported by Pasculle and colleagues (1) to cause pneumonia. It was further characterized by Hébert and associates (2). Most cases of Pittsburgh pneumonia recognized so far have affected immunosuppressed patients (3) and have appeared to be hospital acquired. However, the source of bacteria and means of transmission have not been defined. In our search for L. pneumophila in the hospital environment, we have found Pittsburgh pneumonia agent in respiratory nebulizers. Our findings imply that Pittsburghpneumonia agent, like L. pneumophila, may be disseminated in environmental aerosols.Samples were taken from the couplant reservoirs (Figure 1)...References1. PASCULLE A, MYEROWITZ R, and RINALDO C. New bacterial agent of pneumonia isolated from renal-transplant recipients. Lancet. 1979;1:58-61. CrossrefGoogle Scholar2. HEBERT G, THOMASON B, HARRIS P, HICKLIN M, and MCKINNEY R. "Pittsburgh pneumonia agent": a bacterium phenotypically similar to Legionella pneumophila and identical to the TATLOCK bacterium. Ann Intern Med. 1980;92:53-4. LinkGoogle Scholar3. MYEROWITZ R, PASCULLE A, and DOWLING J. Opportunistic lung infection due to "Pittsburgh pneumonia agent." N Engl J Med. 1979;301:953-8. CrossrefMedlineGoogle Scholar4. MCKINNEY R, THACKER L, and HARRIS P. Four serogroups of Legionnaires' disease bacteria defined by direct immunofluorescence. Ann Intern Med. 1979;90:621-4. LinkGoogle Scholar5. ENGLAND A, MCKINNEY R, SKALIY P, and GORMAN G. A fifth serogroup of Legionella pneumophila. Ann Intern Med. 1980;93:58-9. LinkGoogle Scholar6. CORDES L, WILKINSON H, GORMAN G, FIKES B, and FRASER D. Atypical Legionella-like organisms: fastidious water-associated bacteria pathogenic for man. Lancet. 1979;2:927-30. CrossrefMedlineGoogle Scholar7. MORRIS G, PATTON C, and FEELEY J. Isolation of the Legionnaires' disease bacterium from environmental samples. Ann Intern Med. 1979;90:664-6. LinkGoogle Scholar8. FEELEY J, GORMAN G, WEAVER R, MACKEL D, and SMITH H. Primary isolation media for Legionnaires' disease bacterium. J Clin Microbiol. 1978;8:320-5. CrossrefMedlineGoogle Scholar9. FEELEY J, GIBSON R, and GORMAN G. Charcoal yeast extract agar: primary isolation medium for Legionella pneumophila. J Clin Microbiol. 1979;10:437-41. CrossrefMedlineGoogle Scholar10. MOSS C, WEAVER R, DEES S, and CHERRY W. Cellular fatty acid composition of isolates from Legionnaires' disease. J Clin Microbiol. 1977;6:140-3. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: G. W. GORMAN, B.S.; V.L. YU, M.D.; A. BROWN, M.D.; J.A. HALL, M.S.; W.T. MARTIN, M.S.; W.F. BIBB, M.S.; G.K. MORRIS, Ph.D.; M.H. MAGNUSSEN, M.P.H.; D.W. FRASER, M.D.Affiliations: Center for Disease Control Atlanta, Georgia Veterans Administration Medical Center University of Pittsburgh School of Medicine Pittsburgh, Pennsylvania PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byEvolving Understanding of the Causes of Pneumonia in Adults, With Special Attention to the Role of PneumococcusGuideline for Prevention of Nosocomial PneumoniaDie LegionelleninfektionTransmission of Legionella by Respiratory Equipment and Aerosol Generating DevicesThe Genus LegionellaNosocomial legionnaires disease in a children's hospitalLes barboteurs humidificateurs, facteurs de risque de Legionelloses chez les immunodeprimesLegionellosis in the Compromised HostLegionellosis in the Compromised HostLegionnaires' Disease:Nosocomial legionellosis associated with use of oxygen bubble humidifiers and underwater chest drainsPotential in-hospital modes of transmission of legionella pneumophila. 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