Potential New Cardiovascular Risk Factors
Authors: Bruce L. Rollman, Peter F. Counihan, Charles F. Reynolds
Journal: Annals of Internal Medicine (2000)

Letters2 May 2000Potential New Cardiovascular Risk FactorsBruce L. Rollman, MD, MPH, Peter F. Counihan, MD, and Charles F. Reynolds, MDBruce L. Rollman, MD, MPHUniversity of Pittsburgh; Pittsburgh, PA 15213-2582 (Rollman)University of Pittsburgh; Pittsburgh, PA 15213-2582 (Counihan)University of Pittsburgh; Pittsburgh, PA 15213-2582 (Reynolds)Search for more papers by this author, Peter F. Counihan, MDUniversity of Pittsburgh; Pittsburgh, PA 15213-2582 (Rollman)University of Pittsburgh; Pittsburgh, PA 15213-2582 (Counihan)University of Pittsburgh; Pittsburgh, PA 15213-2582 (Reynolds)Search for more papers by this author, and Charles F. Reynolds, MDUniversity of Pittsburgh; Pittsburgh, PA 15213-2582 (Rollman)University of Pittsburgh; Pittsburgh, PA 15213-2582 (Counihan)University of Pittsburgh; Pittsburgh, PA 15213-2582 (Reynolds)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-132-9-200005020-00022 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Harjai's excellent review (1) of potential cardiovascular risk factors is striking for its inattention to depression, one of the most prevalent (6% to 10% of primary care patients and 16% to 45% of cardiac patients) and inexpensively assessed factors associated with cardiovascular morbidity. Many reports published in the past decade have linked elevated levels of depressive symptoms and major depression to both the development and progression of cardiovascular disease, as well as mortality from it. Comprehensive summaries of the epidemiologic and pathophysiologic evidence have been published in the psychiatric literature (2). However, Harjai may have overlooked this ...References1. Harjai KJ. Potential new cardiovascular risk factors: left ventricular hypertrophy, homocysteine, lipoprotein(a), triglycerides, oxidative stress, and fibrinogen. Ann Intern Med. 1999;131:376-86. LinkGoogle Scholar2. Musselman DL, Evans DL, Nemeroff CB. The relationship of depression to cardiovascular disease: epidemiology, biology, and treatment. Arch Gen Psychiatry. 1998;55:580-92. CrossrefMedlineGoogle Scholar3. Hays RD, Wells KB, Sherbourne CD, Rogers W, Spritzer K. Functioning and well-being outcomes of patients with depression compared with chronic general medical illnesses. Arch Gen Psychiatry. 1995;52:11-9. CrossrefMedlineGoogle Scholar4. Lustman PJ, Griffith LS, Freedland KE, Kissel SS, Clouse RE. Cognitive behavior therapy for depression in type 2 diabetes mellitus. A randomized, controlled trial. Ann Intern Med. 1998;129:613-21. LinkGoogle Scholar5. Blumenthal JA, O'Connor C, Hinderliter A, Fath K, Hegde SB, Miller G, et al . Psychosocial factors and coronary disease. A national multicenter clinical trial (ENRICHD) with a North Carolina focus. North Carolina Medical Journal. 1997;58:440-4. MedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: University of Pittsburgh; Pittsburgh, PA 15213-2582 (Rollman)University of Pittsburgh; Pittsburgh, PA 15213-2582 (Counihan)University of Pittsburgh; Pittsburgh, PA 15213-2582 (Reynolds) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoPotential New Cardiovascular Risk Factors: Left Ventricular Hypertrophy, Homocysteine, Lipoprotein(a), Triglycerides, Oxidative Stress, and Fibrinogen Kishore J. Harjai Metrics 2 May 2000Volume 132, Issue 9Page: 761KeywordsCardiovascular disease riskCardiovascular diseasesHealth careHypertensionMedical risk factorsMorbidityMortalityMyocardial infarctionQuality of lifeToxicity Issue Published: 2 May 2000 CopyrightCopyright © 2000 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...