Emergency Room Patients, Chest Pain, and Thrombolysis
Authors: Robert L. Jayes
Journal: Annals of Internal Medicine (1989)

Letters and Corrections15 October 1989Emergency Room Patients, Chest Pain, and ThrombolysisRobert L. Jayes, MDRobert L. Jayes, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-111-8-685 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editor:Dr. Lee and colleagues (1) are to be congratulated for showing the consequences of applying the published criteria for thrombolysis to emergency room patients with chest pain. However, the authors need to further explain the definition of chest pain used in the analyses. Although patients were stratified by the length of time since the onset of pain, the authors do not mention the duration of the episode of acute chest pain. A duration of 20 minutes was used as a criterion for thrombolytic therapy in one of the published trials (2) cited by the authors; however, the...References1. LeeWeisbergBrandRouanGoldman TMDGL. Candidates for thrombolysis among emergency room patients with acute chest pain. Potential true- and false-positive rates. Ann Intern Med. 1989;110:957-62. LinkGoogle Scholar2. TopolCaliffKereiakesGeorge ERDB. Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) trial. J Am Coll Cardiol. 1987;10:65B-74B. CrossrefMedlineGoogle Scholar1. LeeWeisbergBrandRouanGoldman TMDGL. Candidates for thrombolysis among emergency room patients with acute chest pain. Potential true- and false-positive rates. Ann Intern Med. 1989;110:957-62. LinkGoogle Scholar1. . Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. Lancet. 1988;2;349-60. MedlineGoogle Scholar2. . Long-term effects of intravenous thrombolysis in acute myocardial infarction: final report of the GISSI study. Lancet. 1987;2:871-4. MedlineGoogle Scholar3. . A prospective trial of intravenous streptokinase in acute myocardial infarction (I.S.A.M.): mortality, morbidity, and infarct size at 21 days. N Engl J Med. 1986;314:1465-71. CrossrefMedlineGoogle Scholar4. . Comparison of invasive and conservative strategies after treatment with intravenous tissue plasminogen activator in acute myocardial infarction. Results of the Thrombolysis in Myocardial Infarction (TIMI) Phase II trial. N Engl J Med. 1989;320:618-27. CrossrefMedlineGoogle Scholar5. AndersonRothbardHackworthy JRR. Multicenter reperfusion trial of intravenous anisoylated plasminogen streptokinase activator complex (APSAC) in acute myocardial infarction: controlled comparison with intracoronary streptokinase. J Am Coll Cardiol. 1988;11:1153-63. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: George Washington University Medical Center Washington, D.C. 20037 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByCorrection: Response to Letters on Emergency Room Patients, Chest Pain, and Thrombolysis 15 October 1989Volume 111, Issue 8Page: 685-686KeywordsEmergency departmentIschemia Issue Published: 15 October 1989 PDF DownloadLoading ...