The Prevalence of High-Risk Human Papillomavirus in Women with Different Types of Cervical Cancer
Authors: S. Deblina Datta, Hillard Weinstock
Journal: Annals of Internal Medicine (2008)

Letters19 August 2008The Prevalence of High-Risk Human Papillomavirus in Women with Different Types of Cervical CancerS. Deblina Datta, MD and Hillard Weinstock, MD, MPHS. Deblina Datta, MDFrom the Centers for Disease Control and Prevention, Atlanta, GA 30333.Search for more papers by this author and Hillard Weinstock, MD, MPHFrom the Centers for Disease Control and Prevention, Atlanta, GA 30333.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-149-4-200808190-00015 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:The prevalence of HPV DNA in LSIL and HSIL is known to be very high; therefore, management decisions are based on the presence of the cytologic abnormality alone. The management of LSIL (referral for colposcopy) and that of HSIL (loop electrosurgical excision procedure) are similar in that procedural evaluations are needed (with the exception of special patient populations) and HPV DNA testing would not influence management. The management of atypical squamous cells of undetermined significance (ASC-US), however, is dependent on the results of HPV DNA testing (1). The ALTS (Atypical Squamous Cells of Undetermined Significance/Low-Grade Squamous Intraepithelial Lesion ...References1. Wright TC, Massad LS, Dunton CJ, Spitzer M, Wilkinson EJ, Solomon D. The 2006 ASCCP-Sponsored Consensus Conference. 2006 consensus guidelines for the management of women with abnormal cervical screening tests. J Low Genit Tract Dis. 2007;11:201-22. [PMID: 17917566] CrossrefMedlineGoogle Scholar2. The Atypical Squamous Cells of Undetermined Significance/Low-Grade Squamous Intraepithelial Lesions Triage Study (ALTS) Group. Human papillomavirus testing for triage of women with cytologic evidence of low-grade squamous intraepithelial lesions: baseline data from a randomized trial. J Natl Cancer Inst. 2000;92:397-402. [PMID: 10700419] CrossrefMedlineGoogle Scholar3. Wright TC, Cox JT, Massad LS, Twiggs LB, Wilkinson EJ. ASCCP-Sponsored Consensus Conference. 2001 Consensus Guidelines for the management of women with cervical cytological abnormalities. JAMA. 2002;287:2120-9. [PMID: 11966387] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From the Centers for Disease Control and Prevention, Atlanta, GA 30333.Disclosures: None disclosed. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoHuman Papillomavirus Infection and Cervical Cytology in Women Screened for Cervical Cancer in the United States, 2003–2005 S. Deblina Datta , Laura A. Koutsky , Sylvie Ratelle , Elizabeth R. Unger , Judith Shlay , Tracie McClain , Beth Weaver , Peter Kerndt , Jonathan Zenilman , Michael Hagensee , Cristen J. Suhr , and Hillard Weinstock The Prevalence of High-Risk Human Papillomavirus in Women with Different Types of Cervical Cancer Masaharu Tsubokura , Tsunehiko Komatsu , and Masahiro Kami Metrics 19 August 2008Volume 149, Issue 4Page: 283KeywordsAtypical squamous cellsAtypical squamous cells of uncertain significanceDNAGenetic testingHigh grade squamous intraepithelial lesionsHuman papillomavirusLow grade squamous intraepithelial lesionsResearch designSquamous intraepithelial lesionsTriage ePublished: 19 August 2008 Issue Published: 19 August 2008 Copyright & PermissionsCopyright © 2008 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...