Complete Heart Block and the HLA System
Authors: J.J. VAŹQUEZ RODRIǴUEZ
Journal: Annals of Internal Medicine (1982)

Letters and Corrections1 January 1982Complete Heart Block and the HLA SystemJ.J. VAŹQUEZ RODRIǴUEZ, J. GARCIA SEOANE, A. GIAL AGUADO, J.A. SOBRINO, F.J. ARNALICH BARBADO, A. ARNAIZ VILLENAJ.J. VAŹQUEZ RODRIǴUEZSearch for more papers by this author, J. GARCIA SEOANESearch for more papers by this author, A. GIAL AGUADOSearch for more papers by this author, J.A. SOBRINOSearch for more papers by this author, F.J. ARNALICH BARBADOSearch for more papers by this author, A. ARNAIZ VILLENASearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-96-1-126_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: In the recent UCLA conference on systemic lupus erythematous in pregnancy, Dr. Barrett (1) stated that the most serious neonatal complication in maternal systemic lupus erythematosus is complete heart block. Certainly, it has been shown in recent years that one in three mothers giving birth to babies with complete heart block have, or will develop, systemic lupus erythematosus or another connective tissue disease. Several possible pathogenic mechanisms have been postulated: IgG autoantibodies might cross the placenta and affect the baby; immuno-complexes might cross the placenta and generate complete heart block or otherwise be formed by that baby...References1. BARRETT C. Neonatal outcome of maternal systemic lupus erythematosus, pp. 674-5. In: FINE LG, , moderator. Systemic lupus erythematosus in pregnancy. Ann Intern Med. 1981;94:667-77. MedlineGoogle Scholar2. ESSCHERSCOTT EJ. Congenital heart block and maternal systemic lupus erythematosus. Br Med J. 1979;2:1235-8. CrossrefGoogle Scholar3. MITTALMICKEYSINGALTERASAKI KMDP. Serotyping for homotransplantation: XVIII. Refinement of microdroplet lymphocyte cytotoxicity text. Transplanation. 1969;6:904-24. Google Scholar4. ARNAIZ-VILLENARODRIGUEZ CORDOBAVELAPASCUALCERVEROBOOTELLO ASFJJA. HL-A antigens in a sample of the Spanish Population: common features among Spaniards Bosques and Sardinians. Hum Genet. 1981;58:344-8. CrossrefMedlineGoogle Scholar5. BODMER W, ed. Histocompatibility Testing 1977. Copenhagen: 1980:373. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Universidad Autónoma Madrid Spain PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byProposal for a new definition of congenital complete atrioventricular blockDNA typing of maternal HLA in congenital complete heart block: Comparison with systemic lupus erythematosus and primary Sj�gren's syndromeCongenital heart block immunogenetics. Evidence of an additional role of hla class iii antigens and independence of Ro AutoantibodiesNeonatal lupus erythematosus, multiple thromboses, and monoarthritis in a family with Ro antibodyCardiovascular DiseasesNeonatal lupus erythematosus with heart block: family study of a patient with anti–-ss-a and ss-b antibodies 1 January 1982Volume 96, Issue 1Page: 126-126KeywordsAutoantibodiesBirthCardiovascular therapyConnective tissue diseasesHeartHuman leukocyte antigenLupus erythematosusPathogensPlacentaPregnancy Issue Published: 1 January 1982 PDF downloadLoading ...