Clinical Import of Systolic Hypertension
Authors: ROBERT C. TARAZI
Journal: Annals of Internal Medicine (1978)

Editorial Note1 March 1978Clinical Import of Systolic HypertensionROBERT C. TARAZI, M.D.ROBERT C. TARAZI, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-88-3-426 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn this issue, Rabkin, Mathewson, and Tate (1) add to the chain that links systolic hypertension to major cardiovascular accidents. This evidence has been slowly developing since Gubner (2) pointed out the pathogenetic importance of elevated systolic pressure. Prospective epidemiologic studies confirmed these earlier impressions; cardiac enlargement (3), heart failure (4), coronary arterial disease (5), and strokes (6) were all more closely related to systolic than diastolic levels of pressure. Similar results were obtained in analyses of cardiac (ECG) response to antihypertensive therapy (7).Despite these observations, systolic blood pressure levels continue to be relatively neglected both in practice and...References1. RABKINMATHEWSONTATE SFR: Predicting risk of ischemic heart disease and cerebrovascular disease from systolic and diastolic blood pressures. Ann Intern Med 88:342-345, 1978 LinkGoogle Scholar2. GUBER R: Systolic hypertension: a pathogenic entity. Significance and therapeutic considerations. Am J Cardiol 9:773-776, 1962 CrossrefMedlineGoogle Scholar3. KANNELGORDONOFFUTT WTD: Left ventricular hypertrophy by electrocardiogram: Prevalence, incidence, and mortality in the Framingham study. Ann Intern Med 71:89-105, 1969 LinkGoogle Scholar4. KANNELCASTELLIMCNAMARAMCKEEFEINLEIB WWPPM: Role of blood pressure in the development of congestive heart. N Engl J Med 287:782-787, 1972 CrossrefGoogle Scholar5. KANNELGORDONSCHWARTZ WTM: Systolic versus diastolic blood pressure and risk of coronary heart disease: the Framingham study. Am J Cardiol 27:335-347, 1971 CrossrefMedlineGoogle Scholar6. KANNELWOLFVERTERMCNAMARA WPJP: Epidemiologic assessment of the role of blood pressure in stroke. JAMA 214:301-310, 1970 CrossrefMedlineGoogle Scholar7. IBRAHIMTARAZIDUSTANGIFFORD MRHR: Electrocardiogram in evaluation of resistance to antihypertensive therapy. Arch Intern Med 137:1125-1129, 1977 CrossrefMedlineGoogle Scholar8. TARAZIGIFFORD RR: Clinical significance and management of systolic hypertension, in Cardiovascular Clinics, edited by BREST A. Philadelphia, F.A. Davis Company, in press Google Scholar9. KOCH-WESER J: Correlation of pathophysiology and pharmacology in primary hypertension. Am J Cardiol 32:499-510, 1973 CrossrefMedlineGoogle Scholar10. STRANDGAARDOLESENSKINHOJLASSEN SJEN: Autoregulation of brain circulation in severe arterial hypertension. Br Med J 1:507-510, 1973 CrossrefMedlineGoogle Scholar11. TARAZIMAGRINIDUSTAN RFH: The role of aortic distensibility in hypertension, in Recent Advance in Hypertension, edited by MILLIEZ P, SAFAR M. Reims-France, Boehringer Ingelheim, 1975, pp. 133-142 Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Research Division Cleveland Clinic Foundation Cleveland, Ohio PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByHypertension in the elderly: clinical aspectsComparison of the effects of diuretic therapy and low sodium intake in isolated systolic hypertensionRenin dependency of blood pressure in isolated systolic hypertensionSystolic hypertensionAdrenergic Activity in Systolic HypertensionSystolic Hypertension: Occurrence and Treatment in a Defined Community*Therapy for Systolic HypertensionA. JARRELL RAPER, M.D., F.A.C.P. 1 March 1978Volume 88, Issue 3Page: 426-427KeywordsCoronary heart diseaseHeart diseasesHeart failureHypertensionLongitudinal studiesPathogensProspective studiesStable coronary artery diseaseStrokeSystolic pressure Issue Published: 1 March 1978 PDF DownloadLoading ...