Cellular Proliferation and Hypokalemia
Authors: Fred J. Schiffman, Robert L. Schiffman, Robert M. Rosa
Journal: Annals of Internal Medicine (1977)

Letters and Corrections1 November 1977Cellular Proliferation and HypokalemiaFRED J. SCHIFFMAN, M.D., ROBERT L. SCHIFFMAN, M.D., ROBERT M. ROSA, M.D.FRED J. SCHIFFMAN, M.D.Search for more papers by this author, ROBERT L. SCHIFFMAN, M.D.Search for more papers by this author, ROBERT M. ROSA, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-87-5-635_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: The occurrence of hypokalemia with the blast crisis of acute myeloid leukemia has been described by Mir and co-workers (1a), and accounts of hypokalemia in other leukemic states have been reported by correspondents to Annals of Internal Medicine (1b, 1c). A recent report (2) in the pediatric literature describing eight cases shows that this phenomenon is not confined to adult patients with leukemia.Although the mechanisms responsible for the development of hypokalemia have not been fully delineated, current evidence suggests that it results from renal potassium wasting or intracellular movement of potassium. Some hypokalemic leukemic patients manifest...References1A. MIRBRABINTANGLEYLANDDELAMORE MBOMI: Hypokalemia in acute myeloid leukaemia. Ann Intern Med 82:54-57, 1975 LinkGoogle Scholar1B. GREENBERGERROSENTHALMOLONEY JDW: Hypokalemia in leukemia. Ann Intern Med 82:854, 1975 LinkGoogle Scholar1C. KOSMIDISJAMSEKAXELROD PMA: Hypokalemia in leukemia. Ann Intern Med 82:854-855, 1975 LinkGoogle Scholar2. O'REGANKAPLANCHESNEYAYOUBDRUMMOND SBRJK: Hypokalemia in children with leukemia in relapse. Am J Dis Child 130:937-940, 1976 MedlineGoogle Scholar3. CHESNEY R: Drug-induced hypokalemia. Am J Dis Child 130:1055-1056, 1976 MedlineGoogle Scholar4. MASONHOWESTAYLORROSS DDCB: Effect of human lysozyme (muramidase) on potassium handling by the perfused rat kidney. J Clin Pathol 28:722-727, 1975 CrossrefMedlineGoogle Scholar5. BLOCKBONTING JS: Sodium-potassium activated ATPase and cation transport in normal and leukemic human leukocytes. Enzymol Biol Clin 4:183-198, 1964 CrossrefGoogle Scholar6. JAMESABBOTT GL: Metabolic studies in pernicious anemia. I. Nitrogen and phosphorus metabolism during vitamin B12-induced remission. Metabolism 1:259-270, 1952 MedlineGoogle Scholar7. JOYCE C: Uptake of potassium and sodium by parts of packed human blood cell column. Q J Exp Physiol 43:299-309, 1958 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Beth Israel Hospital Boston, MA 02215 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByAlterations in electrolyte equilibrium in patients with acute leukemiaRenal Failure and Severe Hypokalemia Associated With Acute Myelomonocytic LeukemiaSpurious Hypokalemia in Myeloproliferative Disorders 1 November 1977Volume 87, Issue 5Page: 635-636KeywordsAcute myeloid leukemiaPotassium Issue Published: 1 November 1977 PDF DownloadLoading ...