A Scleroderma-like Syndrome with Fasciitis, Myositis, and Eosinophilia
Authors: H. RALPH SCHUMACHER
Journal: Annals of Internal Medicine (1976)

Letters1 January 1976A Scleroderma-like Syndrome with Fasciitis, Myositis, and EosinophiliaH. RALPH SCHUMACHER, M.D., F.A.C.P.H. RALPH SCHUMACHER, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-84-1-49 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptRecent reports (1, 2) have identified patients who had eosinophilia, hypergammaglobulinemia, and pain and swelling of the extremities with diffuse thickening and inflammation of the fascia or subcutaneous tissues, or both. Shulman's patients (1) had onset after unusual physical exertion. The syndrome resembled scleroderma (3) or mixed connective tissue disease (4), but no patients had Raynaud's phenomenon, impaired esophageal motility, other visceral sclerosis, antinuclear factor, or extractable nuclear antigen (2). This report describes a patient with similar features who also had mild myositis and has achieved remission.A 28-year-old white male engineer noted stiffness, swelling, and painful cramps in his...References1. SHULMAN L: Diffuse fasciitis with hypergammaglobulinemia and eosinophilia: a new syndrome? (abstract) J Rheum 1 (suppl 1):46, 1974 Google Scholar2. RODNANDIBARTOLOMEOMEDSGER GAT: Eosinophilic fasciitis—report of 6 cases of a newly recognized scleroderma-like syndrome (abstract). Clin Res 23:443, 1975 Google Scholar3. RODNAN G: Progressive systemic sclerosis (scleroderma), in Arthritis and Allied Conditions, edited by HOLLANDER JL, MCCARTY DJ. Philadelphia, Lea and Febiger, 1972, pp. 962-1005 Google Scholar4. SHARPIRVINTAN GWE: Mixed connective tissue disease—an apparently distinct rheumatic disease syndrome associated with a specific antibody to an extractable nuclear antigen (ENA). Am J Med 52:148-158, 1972 CrossrefMedlineGoogle Scholar5. VEJJAJIVATEASDALE AG: Serum creatine kinase and physical exercise. Br Med J 1:1653-1654, 1965 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByThe spectrum of eosinophilic myositisFasciitis, perimyositis, myositis, polymyositis, and eosinophiliaCase 4-1990Eosinophilic fasciitis: Clinical spectrum and therapeutic response in 52 casesHistopathology of the Inflammatory MyopathiesDiffuse fasciitis after bone marrow transplantationLess Common Causes of MyositisEntzündliche Erkrankungen der Sehnen, Sehnenscheiden, Bänder, Bursen und FaszienProgressive systemische Sklerodermie (Sklerose)Eosinophile Fasziitis (Shulman-Syndrom)Clinical spectrum of fascial inflammationEosinophilic fasciitis with erosive arthritisEosinophilic FasciitisEOSINOPHILIC FASCIITIS: AN ULTRASTRUCTURAL AND IMMUNOHISTOCHEMICAL STUDY OF THE INTERMEDIATE FILAMENT PROTEIN SKELETIN IN REGENERATING MUSCLE FIBRESEosinophilic fasciitisEosinophilic fasciitis: report of a 22-year followup studyFasciitis with Eosinophilia:.Diffuse fasciitis with eosinophilia: A steroid-responsive variant of sclerodermaScleroderma and Other Diseases Associated with Cutaneous SclerosisThe fascia in systemic sclerodermaDiffuse Fasciitis with EosinophiliaDiffuse fasciitis with eosinophiliaDiffuse Fasciitis and Eosinophilia with Symmetric PolyarthritisJEROME ROSENTHAL, M.D., MERRILL D. BENSON, M.D.Eosinophilic fasciitisEosinophilie Fasciitis: A Problem in Differential DiagnosisDIFFUSE FASCIITIS WITH EOSINOPHILIA (SHULMAN'S DISEASE)Eosinophilic fasciitis: An early variant of sclerodermaCase 31-1979Progressive Systemic Sclerosis: PseudosclerodermaSubcutaneous morphoea: a clinical study of sixteen casesThe Shulman syndrome: report of a further caseReverse transcriptase in a patient with sclerodermaEosinophilic Fasciitis: Review and Report of Six CasesEosinophilic FasciitisR.B. LEWIS, M.D., W.B. VAN VALKENBURG, M.D.Eosinophilic fasciitis. Case report and review of the literature.Rheumatologie Conditions of the WristSclerodermaEosinophilic polymyositis 1 January 1976Volume 84, Issue 1Page: 49-50KeywordsAntigensEngineersEosinophiliaHypergammaglobulinemiaInflammationMixed connective tissue diseaseMyositisRaynaud syndromeSclerodermaStiffness Issue Published: 1 January 1976 PDF DownloadLoading ...