Metabolic Effects of Tetracycline
Authors: MARK H. LEPPER
Journal: Annals of Internal Medicine (1963)

Editorials1 March 1963Metabolic Effects of TetracyclineMARK H. LEPPER, M.D.MARK H. LEPPER, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-58-3-553 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn formulating his theories on the mechanism of chemotherapeutic effects, Ehrlich was greatly influenced by the evidence in his studies on dyes of the specificity of the immune reaction and the specificity of the tissue in the host. The dominant thought that evolved was that chemically defined substances could be found which would have a selective deleterious effect on the parasite. He originated the famous "magic bullet" metaphor for destruction of the parasite without injury to the tissue cell. Although the ideal result would have been complete destruction of the invader and complete lack of effect on the host, Ehrlich...References1. 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COHLANBEVELANDERBROSS SQGS: Effect of tetracycline on bone growth in the premature infant, in Antimicrobial Agents and Chemotherapy 1961, Braun-Brumfield Inc., Ann Arbor, Michigan, 1962, p. 340. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Department of Preventive Medicine University of Illinois College of Medicine Chicago 12, Illinois PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe Pharmacologic Management of the Syndrome of Inappropriate Secretion of Antidiuretic HormoneCorrection of Antidiuresis by DemeclocyclineEffects of tetracycline on pancreatic protein synthesis and secretion in pigeonsTetracycline in the treatment of rheumatoid arthritis. A double blind controlled studyDer Einfluß von anabolen Hormonen und von Diät auf den myokardialen Gehalt an energiereichen Phosphaten während der InfarktheilungPuzzling HematuriaComplications of tetracycline therapyEnvironment and the Kidney 1 March 1963Volume 58, Issue 3Page: 553-556KeywordsSpecificityTetracyclines Issue Published: 1 March 1963 PDF downloadLoading ...