Acute Aortic Valvular Insufficiency Due to Isolated Myxomatous Degeneration
Authors: GORDON N. OLINGER
Journal: Annals of Internal Medicine (1978)

Brief Reports1 June 1978Acute Aortic Valvular Insufficiency Due to Isolated Myxomatous DegenerationGORDON N. OLINGER, M.D., MICHAEL E. KORNS, M.D., LAWRENCE I. BONCHEK, M.D.GORDON N. OLINGER, M.D.Search for more papers by this author, MICHAEL E. KORNS, M.D.Search for more papers by this author, LAWRENCE I. BONCHEK, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-88-6-807 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAortic valvular insufficiency in Marfan's syndrome is ordinarily due to aortic dilatation (1). The aortic media shows degeneration of elastic fibers and replacement with mucopolysaccharide; the aortic valve usually lacks these findings, although leaflet redundancy, fenestration, and rupture are recognizable. Aortic pathology may be similar in the forme fruste of Marfan's where the noncardiovascular manifestations of mesodermal dystrophy are variable. Isolated myxomatous degeneration of the aortic valve is rare, however, and in the only three reported cases, perforations of valve leaflets caused insufficiency. (2, 3). We report herein the only known case of acute aortic insufficiency occurring without perforation in...References1. MCKUSICK V: Heritable Disorders of Connective Tissue. Saint Louis, C.V. Mosby Company, 1972, pp. 61-223 Google Scholar2. ESTEVEZ C, DILLION J, WALKER J, FEIGENBAUM H, and CHANG S: Echocardiographic manifestations of aortic cusp rupture in a myxomatous aortic valve. Chest 69:685-687, 1976 CrossrefMedlineGoogle Scholar3. O'BRIEN K, HITCHCOCK G, BARRETT-BOYES B, and LOWE J: Spontaneous aortic cusp rupture associated with valvular myxomatous transformation. Circulation 37:273-278, 1968 CrossrefGoogle Scholar4. FREIDEN J, HURWITT E, and LEADER E: Ruptured aortic cusp associated with an heritable disorder of connective tissue. AM J Med 33:615-618, 1962 CrossrefMedlineGoogle Scholar5. READ R, THAL A, and WENDT V: Symptomatic valvular myxomatous transformation (the floppy valve syndrome): a possible forme fruste of the Marfan's snydrome. Circulation 32:897-910, 1965 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: GORDON N. OLINGER, M.D.; MICHAEL E. KORNS, M.D.; LAWRENCE I. BONCHEK, M.D.Affiliations: Department of Thoracic and Cardiovascular Surgery and Department of Pathology The Medical College of Wisconsin Milwaukee, Wisconsin PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byHistiocytoid cardiomyopathy in an eleven-month-old infant: A case report and literature reviewHistiocytoid cardiomyopathy and ventricular non-compaction in a case of sudden death in a female infantFestschrift for Dr. John M. Opitz: Pathogenesis of cardiac conduction disorders in children genetic and histopathologic aspectsAortic InsufficiencyMetabolic Cardiomyopathy of ChildhoodHeritable Disorders of Connective Tissue 1 June 1978Volume 88, Issue 6 Page: 807-808 Keywords Aortic valve Marfan syndrome ePublished: 1 December 2008 Issue Published: 1 June 1978 PDF downloadLoading ...