Tissue Plasminogen Activator and Cholesterol Crystal Embolization
Authors: Manick Bhardwaj
Journal: Annals of Internal Medicine (1989)

Letters and Corrections15 October 1989Tissue Plasminogen Activator and Cholesterol Crystal EmbolizationManick Bhardwaj, MD, Richard Goldweit, MD, Jay Erlebacher, MD, Massoud Kashani, MD, David Levin, MD, George Leber, MDManick Bhardwaj, MDSearch for more papers by this author, Richard Goldweit, MDSearch for more papers by this author, Jay Erlebacher, MDSearch for more papers by this author, Massoud Kashani, MDSearch for more papers by this author, David Levin, MDSearch for more papers by this author, George Leber, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-111-8-687 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editor:Cholesterol crystal embolization has been seen frequently in patients who undergo angiographic procedures after thrombolytic therapy (1). We describe a patient whose cholesterol crystal embolization occurred spontaneously after recombinant tissue-type plasminogen activator thrombolysis without an antecedent invasive vascular procedure. A 62-year-old woman with a history of hypertension and hypercholesterolemia presented with 2 hours of chest pain and electrocardiographic changes indicating acute inferior myocardial infarction. She had no history of angiography or recent surgical procedures. At initial examination there was no skin rash. Peripheral pulses were normal, but a systolic bruit was heard just below the umbilicus. She...Reference1. SchwartzMcDonald MG. Cholesterol embolization syndrome: occurrence after intravenous streptokinase therapy for myocardial infarction. JAMA. 1987;258:1934-5. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: Manick Bhardwaj, MD; Richard Goldweit, MD; Jay Erlebacher, MD; Massoud Kashani, MD; David Levin, MD; George Leber, MDAffiliations: Englewood Hospital Englewood, NJ 07631 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAcute Kidney Injury in Acute Ischemic Stroke Patients in Clinical TrialsThrombolyticsCholesterol Embolization Syndrome Induced by Thrombolytic TherapyAtheroembolic disease following administration of tissue plasminogen activator (TPA)Isolated splenic infarction following left cardiac catheterization: Case report and a review of the literatureSevere Adverse Cutaneous Reactions to DrugsProspective Assessment of Cholesterol Embolization in Patients With Acute Myocardial Infarction Treated With Thrombolytic vs Conservative TherapyPain Relief and Clinical Improvement Temporally Related to the Use of Pentoxifylline in a Patient with Documented Cholesterol Emboli—A Case ReportCase 38-1993Cholesterol embolization syndrome after intravenous tissue plasminogen activator for acute myocardial infarctionCholesterol Embolism in Intensive Care PatientsDrugs affecting blood coagulation and hemostasis 15 October 1989Volume 111, Issue 8Page: 687-688KeywordsAngiographyCholesterolElectrocardiographyHypertensionIschemiaMyocardial infarctionRashesTissue plasminogen activator ePublished: 1 December 2008 Issue Published: 15 October 1989 PDF downloadLoading ...