Metabolically Healthy Overweight and Obesity
Authors: Jean-Philippe Chaput, Arya M. Sharma
Journal: Annals of Internal Medicine (2014)

Letters1 April 2014Metabolically Healthy Overweight and ObesityJean-Philippe Chaput, PhD and Arya M. Sharma, MD, PhDJean-Philippe Chaput, PhDFrom University of Ottawa, Ottawa, Ontario, Canada; and University of Alberta, Edmonton, Alberta, Canada. and Arya M. Sharma, MD, PhDFrom University of Ottawa, Ottawa, Ontario, Canada; and University of Alberta, Edmonton, Alberta, Canada.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/L14-5007 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITORKramer and colleagues (1) conclude that "there is no healthy pattern of increased weight." However, all of the studies included in this analysis define unhealthy obesity as the presence of at least 2 components of the metabolic syndrome. Thus, by definition, persons with just 1 risk factor (such as hypertension, elevated fasting glucose levels, or hypercholesterolemia) would be considered "metabolically healthy." It is not surprising that this group has an elevated risk for cardiovascular events. We believe that this meta-analysis adds to the confusion on the topic by defining "healthy obesity" by criteria that we would consider ...References1. Kramer CK, Zinman B, Retnakaran R. Are metabolically healthy overweight and obesity benign conditions?: A systematic review and meta-analysis. Ann Intern Med. 2013;159:758-69. [PMID: 24297192] LinkGoogle Scholar2. Sharma AM, Kushner RF. A proposed clinical staging system for obesity. Int J Obes (Lond). 2009;33:289-95. [PMID: 19188927] CrossrefMedlineGoogle Scholar3. Padwal RS, Pajewski NM, Allison DB, Sharma AM. Using the Edmonton obesity staging system to predict mortality in a population-representative cohort of people with overweight and obesity. CMAJ. 2011;183:1059-66. [PMID: 21844111] CrossrefMedlineGoogle Scholar4. Kuk JL, Ardern CI, Church TS, Sharma AM, Padwal R, Sui X, et al. Edmonton Obesity Staging System: association with weight history and mortality risk. Appl Physiol Nutr Metab. 2011;36:570-6. [PMID: 21838602] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From University of Ottawa, Ottawa, Ontario, Canada; and University of Alberta, Edmonton, Alberta, Canada.Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L14-0020. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoAre Metabolically Healthy Overweight and Obesity Benign Conditions? Caroline K. Kramer , Bernard Zinman , and Ravi Retnakaran Metabolically Healthy Overweight and Obesity Dorit Samocha-Bonet , Antony D. Karelis , and Rémi Rabasa-Lhoret Metabolically Healthy Overweight and Obesity Nathalie Esser , André J. Scheen , and Nicolas Paquot Metabolically Healthy Overweight and Obesity Gerson T. Lesser Metabolically Healthy Overweight and Obesity Juhee Cho , Yoosoo Chang , and Seungho Ryu Metabolically Healthy Overweight and Obesity Katherine M. Flegal Metabolically Healthy Overweight and Obesity Caroline K. Kramer , Bernard Zinman , and Ravi Retnakaran Metabolically Healthy Overweight and Obesity Dorit Samocha-Bonet , Antony D. Karelis , and Rémi Rabasa-Lhoret Metabolically Healthy Overweight and Obesity Nathalie Esser , André J. Scheen , and Nicolas Paquot Metabolically Healthy Overweight and Obesity Katherine M. Flegal Metabolically Healthy Overweight and Obesity Gerson T. Lesser Metabolically Healthy Overweight and Obesity Caroline K. Kramer , Bernard Zinman , and Ravi Retnakaran Metabolically Healthy Overweight and Obesity Juhee Cho , Yoosoo Chang , and Seungho Ryu Metrics Cited byObesity and Cardiovascular Disease 1 April 2014Volume 160, Issue 7Page: 513KeywordsDyslipidemiaGlucoseHypertensionMedical risk factorsMetabolic analysisMetabolic syndromeObesityOverweightPrimary hypertension ePublished: 1 April 2014 Issue Published: 1 April 2014 Copyright & PermissionsCopyright © 2014 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...