Treatment of Acute Megakaryocytic Leukemia
Authors: WILLIAM R. FRIEDENBERG
Journal: Annals of Internal Medicine (1986)

Letters and Corrections1 February 1986Treatment of Acute Megakaryocytic LeukemiaWILLIAM R. FRIEDENBERG, M.D., JOSEPH J. MAZZA, M.D., JOHN D. HINES, M.D.WILLIAM R. FRIEDENBERG, M.D.Search for more papers by this author, JOSEPH J. MAZZA, M.D.Search for more papers by this author, JOHN D. HINES, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-104-2-280_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Recent position papers and editorials in theAnnalshave discussed the French-American-British (FAB) classification of acute myeloid leukemia (1-4). In addition to giving reproducible results, a classification of acute leukemia should allow more definitive treatment based on the classification. Complete remissions have been obtained by the Eastern Cooperative Oncology Group in 71% of patients using daunorubicin, cytarabine, and 6-thioguanine (DAT) (5). The time to recovery of the platelet count to greater than 100 000/mm3in patients obtaining a complete remission was approximately 26 days and usually preceded the rise in neutrophil count (> 1000/mm3) (5). However, when...References1. BLOOMFIELDRUNNING CR. FAB M7: acute megakaryoblastic leukemia—beyond morphology [Editorial]. Ann Intern Med. 1985;103:450-2. LinkGoogle Scholar2. BENNETTCATOVSKYDANIEL JDM. Criteria for the diagnosis of acute leukemia of megakaryocyte lineage (M7): a report of the French-American-British Cooperative Group. Ann Intern Med. 1985;103:460-2. LinkGoogle Scholar3. BLOOMFIELDBRUNNING CR. The revised French-American-British classification of acute myeloid leukemia: is new better [Editorial]? Ann Intern Med. 1985;103:614-6. LinkGoogle Scholar4. BENNETTCATOVSKYDANIEL JDM. Proposed revised criteria for the classification of acute myeloid leukemia: a report of the French-American-British Cooperative Group. Ann Intern Med. 1985;103:620-5. LinkGoogle Scholar5. CASSILETHKAHNSILBERWEILER PSRC. Induction therapy and intensive consolidation with daunorubicin, cytosine arabinoside and 6-thioguanine in adult acute nonlymphoblastic leukemia. Cancer Clin Trials. 1981;4:125-8. MedlineGoogle Scholar6. HINESMAZZAOKEN JJM. High-dose cytosine arabinoside and mAMSA induction and consolidation in patients with previously untreated de novo acute nonlymphocytic leukemia: phase I pilot study for the Eastern Cooperative Oncology Group. Semin Oncol. 1985;12:117-9. MedlineGoogle Scholar1. BENNETTCATOVSKYDANIEL JDM. Criteria for the diagnosis of acute leukemia of megakaryocyte lineage (M7): a report of the French-American-British Cooperative Group. Ann Intern Med. 1985;103:460-2. LinkGoogle Scholar2. HUANGLINICHOLSYOUNGKATZMAN MCWJJ. Acute leukemia with megakaryocytic differentiation: a study of 12 cases identified immunocytochemically. Blood. 1984;64:427-39. CrossrefMedlineGoogle Scholar3. RUIZ-ARGUELLESMARIN-LOPEZLOBATO-MENDIZABALRUIZ-ARGUELLESNICHOLSKATZMAN GAEAWJ. Acute megakaryoblastic leukemia: a prospective study of its identification and treatment [Abstract]. Blood. 1984;64(6 suppl 1):173a. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: WILLIAM R. FRIEDENBERG, M.D.; JOSEPH J. MAZZA, M.D.; JOHN D. HINES, M.D.Affiliations: Marshfield Clinic Marshfield, WI 54449-5777 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 February 1986Volume 104, Issue 2Page: 280-281KeywordsAcute myeloid leukemiaNeutrophilsPlatelets ePublished: 1 December 2008 Issue Published: 1 February 1986 PDF downloadLoading ...