Medical Food and Food Supplements: Not Always as Safe as Generally Assumed
Authors: Stephan Reichenbach, Peter Jüni
Journal: Annals of Internal Medicine (2012)

Editorials19 June 2012Medical Food and Food Supplements: Not Always as Safe as Generally AssumedStephan Reichenbach, MD, MSc and Peter Jüni, MDStephan Reichenbach, MD, MScFrom University of Bern, 3012 Bern, Switzerland. and Peter Jüni, MDFrom University of Bern, 3012 Bern, Switzerland.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-156-12-201206190-00012 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Osteoarthritis is the most common form of joint disease and the leading cause of musculoskeletal pain and disability in adults (1, 2), but it remains one of the few chronic diseases of aging for which there is little, if any, effective treatment (3). It is musculoskeletal pain, rather than radiographic changes, that results in large numbers of medical consultations. The relationship between pain and signs of osteoarthritis on radiographs is weak to moderate; some patients with severe radiographic osteoarthritis have little or no joint pain (4), whereas many patients with regular joint pain do not show relevant signs of osteoarthritis ...References1. Jinks C, Jordan K, Croft P. Measuring the population impact of knee pain and disability with the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Pain. 2002;100:55-64. [PMID: 12435459] CrossrefMedlineGoogle Scholar2. McAlindon TE, Snow S, Cooper C, Dieppe PA. Radiographic patterns of osteoarthritis of the knee joint in the community: the importance of the patellofemoral joint. Ann Rheum Dis. 1992;51:844-9. [PMID: 1632657] CrossrefMedlineGoogle Scholar3. Felson DT. Developments in the clinical understanding of osteoarthritis. Arthritis Res Ther. 2009;11:203. [PMID: 19232065] CrossrefMedlineGoogle Scholar4. Lawrence JS, Bremner JM, Bier F. Osteo-arthrosis. 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[PMID: 19033592] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From University of Bern, 3012 Bern, Switzerland.Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M12-0992.Corresponding Author: Peter Jüni, MD, Institute of Social and Preventive Medicine, University of Bern, Finkenhubelweg 11, 3012 Bern, Switzerland; e-mail, [email protected]unibe.ch.Current Author Addresses: Drs. Reichenbach and Jüni: Institute of Social and Preventive Medicine, University of Bern, Finkenhubelweg 11, 3012 Bern, Switzerland. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoAcute Liver Injury due to Flavocoxid (Limbrel), a Medical Food for Osteoarthritis Naga Chalasani , Raj Vuppalanchi , Victor Navarro , Robert Fontana , Herbert Bonkovsky , Huiman Barnhart , David E. Kleiner , Jay H. Hoofnagle , and Metrics Cited ByThe metabolome of [2-14C](−)-epicatechin in humans: implications for the assessment of efficacy, safety and mechanisms of action of polyphenolic bioactivesSafety and anti-hyperglycemic efficacy of various tea types in miceInappropriate Usage of Dietary Supplements in Patients by Miscommunication with Physicians in JapanA survey of dietary supplement use among Italian sporting club athletesImpact of genetic risk assessment on nutrition-related lifestyle behaviours 19 June 2012Volume 156, Issue 12Page: 894-895KeywordsArthralgiaDrugsFoodLiverOsteoarthritisPreventive medicineRheumatologySafety ePublished: 19 June 2012 Issue Published: 19 June 2012 CopyrightCopyright © 2012 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...