Anaphylactic Shock and Vitamin K_1
Authors: Javier de la Rubia
Journal: Annals of Internal Medicine (1989)

Letters and Corrections1 June 1989Anaphylactic Shock and Vitamin K1Javier de la Rubia, MD, Enric Grau, MD, Isabel Montserrat, MD, Isabel Zuazu, MD, Antonio Payá, MDJavier de la Rubia, MDSearch for more papers by this author, Enric Grau, MDSearch for more papers by this author, Isabel Montserrat, MDSearch for more papers by this author, Isabel Zuazu, MDSearch for more papers by this author, Antonio Payá, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-110-11-943_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editor: Vitamin K1 (phytonadione) is used mainly as a corrector when there is a high risk of hemorrhage due to vitamin K deficiency. Among the reported complications linked to intravenous infusion of vitamin K1 the most serious is anaphylactic collapse caused by rapid intravenous infusion of the undiluted drug. We report a case of anaphylactic shock that developed during slow intravenous infusion of diluted vitamin K1.A 41-year-old woman who had had rheumatic fever during childhood and had residual mitral disease underwent right oophorectomy in 1983 that required intravenous administration of vitamin K1. In October 1986, she had...References1. Pelletier G, Attali P, and Ink O. Arrèt cardiorespiratoire après injection intraveineuse de vitamine K1. Gastroenterol Clin Biol. 1986;10:615. MedlineGoogle Scholar2. Rich C and Drage C. Severe complications of intravenous phytadione therapy. Two cases with one fatality. Postgrad Med. 1982;72:303-6. CrossrefMedlineGoogle Scholar3. Labatut A, Sorbette F, and Virenque C. Shock states during injection of vitamin K1. Therapie. 1988;43:58. MedlineGoogle Scholar4. Lefrère J and Girot R. Acute cardiovascular collapse during intravenous vitamin K1 injection. Thromb Haemost. 1987;58:790. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: Javier de la Rubia, MD; Enric Grau, MD; Isabel Montserrat, MD; Isabel Zuazu, MD; Antonio Payá, MDAffiliations: Hospital de la Santa Creu i Sant Pau Barcelona Spain PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byVitamin K – sources, physiological role, kinetics, deficiency, detection, therapeutic use, and toxicityINR Response to Low-Dose Vitamin K in Warfarin PatientsRandomized, placebo-controlled trial of orally administered vitamin K1 for warfarin-associated coagulopathy in Chinese patients with mechanical heart valvesCerebral Hemorrhage and High INRCharacterizing the Severe Reactions of Parenteral Vitamin K1RodenticidesGuideline for Reversal of Antithrombotics in Intracranial HemorrhageRodenticidesLong-Acting Anticoagulant Rodenticide (Superwarfarin) Poisoning: A Review of Its Historical Development, Epidemiology, and Clinical ManagementAnticoagulantsFat-Soluble Vitamins and Wound HealingSurgical delay in acute admissions on warfarin: are we doing enough?The Use ???of Vitamin K in Patients on Anticoagulant TherapyAnaphylaxis after low dose intravenous vitamin KThe incidence of anaphylaxis following intravenous phytonadione (vitamin K1): a 5-year retrospective reviewPractitioner report involving intravenous use of vitamin K1 prompts label review and revisionEfficacy and Safety of Intravenous Phytonadione (Vitamin K1) in Patients on Long-term Oral Anticoagulant TherapyEvaluation and Survey of Intravenous Vitamin K 1 for Treatment of Coagulopathy in Critically Ill PatientsAnticoagulation TherapyVitamin K Modulates Cardiac Action Potential by Blocking Sodium and Potassium Ion ChannelsPhytonadione Therapy in a Multiple-Drug Overdose Involving WarfarinLong-Acting Anticoagulant Overdose: Brodifacoum Kinetics and Optimal Vitamin K DosingCutaneous allergic reaction to intramuscular vitamin K1Modern Management of Prosthetic Valve AnticoagulationGastrointestinal problems in acute renal failureVitamin K-induced cardiovascular collapseFinal Report on the Safety Assessment of Peg-30,-33,-35,-36, ANd-40 Castor Oil and Peg-30 and-40 Hydrogenated Castor OilAnaphylactic Shock Following Intravenous Vitamin K 1Vitamin K 1 -Induced Anaphylactic ShockOral Vitamin K 1 : An Option To Reduce Warfarin'S ActivityConservative Treatment of Overanticoagulated PatientsHypersensitivity Reactions Associated with Parenteral Nutrition: Case Report and Review of the LiteratureFatal rodenticide poisoning with brodifacoumVitamin K, and Anaphylactic ShockVitamins 1 June 1989Volume 110, Issue 11Page: 943-943KeywordsDrugsHemorrhageOophorectomyRheumatic feverShockVitamin K ePublished: 1 December 2008 Issue Published: 1 June 1989 PDF downloadLoading ...