Generalized Myositis in Behçet Disease: Treatment with Cyclosporine
Authors: Thomas Lingenfelser, Heinz Duerk, Andreas Stevens, Thomas Grossmann, Markus Knorr, Johannes G. Saal
Journal: Annals of Internal Medicine (1992)

Brief Reports15 April 1992Generalized Myositis in Behçet Disease: Treatment with CyclosporineThomas Lingenfelser, MD, Heinz Duerk, PhD, MD, Andreas Stevens, MD, Thomas Grossmann, MD, Markus Knorr, MD, Johannes G. Saal, MDThomas Lingenfelser, MDSearch for more papers by this author, Heinz Duerk, PhD, MDSearch for more papers by this author, Andreas Stevens, MDSearch for more papers by this author, Thomas Grossmann, MDSearch for more papers by this author, Markus Knorr, MDSearch for more papers by this author, Johannes G. Saal, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-116-8-651 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn 1937, Hulusi Behçet first described a clinical triad of recurrent oral and genital aphthous ulcerations with purulent iritis (1). The spectrum of this disease has since enlarged (2). An international study group (3) recently agreed that diagnosis should be based on the presence of oral ulcerations in association with any two of the following: genital ulcerations, typical defined eye or skin lesions, or a positive pathergy test (the tendency to form cutaneous nodular pustules at the site of simple needlesticks). Myositis was not considered to be a feature of Behçet disease (2, 3), and its association with the disease...References1. Behçet H. Über rezidivierende Aphthöse, durch ein Virus verursachte Geschwüre am Mund, am Auge und an den Genitalien. Dermatol Wochenscher. 1937;36:1152-7. Google Scholar2. O'Dufly J. Behçet's syndrome [Editorial]. N Engl J Med. 1990;322:326-7. CrossrefMedlineGoogle Scholar3. .International Study Group for Behçet's Disease. Lancet. 1990;1:1078-80. Google Scholar4. ArkinRothschildFlorendoPopoff CBNN. Behçet syndrome with myositis. A case report with pathologic findings. Arthritis Rheum. 1980;23:600-4. CrossrefMedlineGoogle Scholar5. LangLaxerThornerGreenbergSilverman BRPME. Pediatric onset of Behçet's syndrome with myositis: case report and literature review illustrating unusual features. Arthritis Rheum. 1990;33:418-25. CrossrefMedlineGoogle Scholar6. FinucaneDoyleFerrissMolloyMurnaghan PCJMD. Behçet's syndrome with myositis and glomerulonephritis. Br J Rheumatol. 1985;24:372-5. CrossrefMedlineGoogle Scholar7. TheoharisRondierEfthymiouForest GJTM. Un nouveau cas de myosite localisée au cours d'une maladie d'Adamantiades-Behçet. Rev Rhum Mal Osteoartic. 1988;55:965-6. MedlineGoogle Scholar8. YaziciPazarliBarnesTuzunOzyazganSilman HHCYYA. A controlled trial of azathioprine in Behçet's syndrome. N Engl J Med. 1990;322:281-5. CrossrefMedlineGoogle Scholar9. NussenblattPalestineChanMochizukiYancey RACMK. Effectiveness of cyclosporin therapy for Behçet's disease. Arthritis Rheum. 1985;28:671-9. CrossrefMedlineGoogle Scholar10. MasudaNakajimaUrayamaNakaeKogureInaba KAAKMG. Double-masked trial of cyclosporin versus colchicine and long-term open study of cyclosporin in Behçet's disease. Lancet. 1989; 1:1093-6. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: From Eberhard-Karls University, Tübingen, Germany. For current author addresses, see end of text. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byInflammatory muscle involvement in systemic vasculitis: A systematic reviewMuscular atrophy and weakness in the lower extremities in Behçet’s disease: A case report and review of literatureAsymptomatic HyperCKemiaLocomotor System DiseaseSuccessful treatment of refractory Behçet’s myositis with Tumor Necrosis Factor inhibitorSecondary myopathy due to systemic diseasesFocal myositis: A reviewMuscle involvement in two Behçet cases: magnetic resonance imaging and histology findingsMuscular involvement of Behçet's disease: ultrasonography, computed tomography, and magnetic resonance imaging findingsLipid Storage Myopathy in Behçet's Disease: A Rare Cause of Elevated Serum Creatine Kinases LevelsA case of recurrent myositis as the main manifestation of Behçet diseaseLocomotor System Disease in Behçet’s SyndromeMaladie de BehçetEnfermedad de BehçetMyopathie beim Behçet-SyndromMyonecrosis of Behcet’s diseaseBMyositis and scleritis associated with Behçet's disease: an atypical presentationAcquired MyopathiesBehçet’s Disease — A Rheumatologic PerspectiveIntestinal Behçet's disease associated with generalized myositisMuscular necrotizing vasculitis as the initial manifestation of Behçet's diseaseBehçet’s disease: an immune-mediated vasculitis involving vessels of all sizesMuscular involvement in Beh çet's disease: Case report and review of the literatureImmunosuppressive Agents in Skin DisordersCYCLOSPORINE, FK-506, RAPAMYCIN, AND OTHER IMMUNOMODULATORS 15 April 1992Volume 116, Issue 8Page: 651-653KeywordsGenital anatomyLesionsMuscular dystrophiesMyositisNeurologyOphthalmologyUlcers ePublished: 1 December 2008 Issue Published: 15 April 1992 PDF downloadLoading ...