Amylase and lsoamylase Activities in Renal Insufficiency
Authors: J. EDWARD BERK
Journal: Annals of Internal Medicine (1979)

Brief Reports1 March 1979Amylase and lsoamylase Activities in Renal InsufficiencyJ. EDWARD BERK, M.D., LOUIS FRIDHANDLER, Ph.D., RUSSELL L. NESS, M.D.J. EDWARD BERK, M.D.Search for more papers by this author, LOUIS FRIDHANDLER, Ph.D.Search for more papers by this author, RUSSELL L. NESS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-90-3-351 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptImpaired renal function may be associated with rises in serum amylase activity (1-5) and the ratio of amylase clearance to creatinine (Cam/Ccr) (3, 4, 6). These deviations cloud the interpretation of abdominal pain and hyperamylasemia in patients with chronic renal disease as indicators of complicating acute pancreatitis (5). This study is primarily concerned with the effect of marked renal impairment on the serum activities and relative urinary clearances of the pancreatic-type (P-type) and salivary-type (S-type) isoenzymes of amylase about which information is limited at present (3).The study group was composed of 36 patients with advanced renal insufficiency. Twenty-four were...References1. BAILEYKATZHAMPERSMERRILL GACJ: Alterations in serum enzymes in chronic renal failure. JAMA 213:2263-2265, 1970 CrossrefMedlineGoogle Scholar2. SCHÖNEBECKSÖDERBERG JM: Serum amylase in renal failure. Scand J Urol Nephrol 5:257-262, 1971 CrossrefMedlineGoogle Scholar3. MORTONTEDESCOHARTERALPERS WFHD: Serum amylase determinations and amylase to creatinine clearance ratios in patients with chronic renal insufficiency. Gastroenterology 71:594-598, 1976 CrossrefMedlineGoogle Scholar4. PEDERSENBROCKKORNERUP EAH: Serum amylase activity and renal amylase activity clearance in patients with severely impaired renal function and in patients treated with renal allotransplantation. Scand J Clin Lab Invest 36:137-140, 1976 CrossrefMedlineGoogle Scholar5. ROBINSONALPGRANTLAWRENCE DMAJ: Pancreatitis and renal disease. Scand J Gastroenterol 12:17-20, 1977 CrossrefMedlineGoogle Scholar6. LEVITTRAPOPORTCOOPERBAND MMS: The renal clearance of amylase in renal insufficiency, acute pancreatitis and macroamylasemia. Ann Intern Med 71:919-925, 1969 LinkGoogle Scholar7. HEFFERNONFRIDHANDLERBERKSHIMAMURA JLJJ: Assay of amylase and isoamylase activities in serum and urine. Am J Gastroenterol 67:473-477, 1977 MedlineGoogle Scholar8. FRIDHANDLERBERKUEDA LJM: Isolation and measurement of pancreatic amylase in human serum and urine. Clin Chem 18:1493-1497, 1972 CrossrefMedlineGoogle Scholar9. NORDWEISCÖLLE HHH: Untersuchungen zum Stoffwechsel der Serumamylase. Verh Dtsch Ges Inn Med 79:868-970, 1973 MedlineGoogle Scholar10. DUANEFRERICHSLEVITT WRM: Distribution, turnover and mechanism of renal excretion of amylase in the baboon. J Clin Invest 50:156-165, 1971 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: College of Medicine University of California Irvine Orange, California PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPancreatic Enzymes in End-stage Renal Disease Patients on Maintenance HemodialysisHydrolases acting on glycosidic bonds: chromatographic and electrophoretic separationsSerum procarboxypeptidase B, amylase and lipase in chronic renal failureα-Amylase and Isoamylase Levels in Renal Transplant Recipients Compared to Uremic PatientsThe value of α-amylase and isoamylase determination in chronic renal failure patientsPancreatic enzymes in chronic renal failure and transplant patientsHistological pancreatitis in end-stage renal diseaseCAPD and Pancreatitis: No ConnectionPancreatitis in acute hemolysisPancreatic-type hyperamylasemia in end-stage renal diseasePancreatic enzymes in uremic patients with or without dialysisFrequency of pancreatitis in fulminant hepatic failure using isoenzyme markers.The Influence of Hydrochlorothiazide and Tripamide on Serum and Urinary AmylaseSerum Amylase and Isoamylase in Chronic Renal FailureEvaluation of a Peritoneal Dialysis Solution Containing PolymerThe Effects of Long-Term Hemodialysis on Gastrointestinal FunctionClinical evaluation of amylase-creatinine clearance ratio and amylase isoenzyme clearance in chronic renal failureGastrointestinal Complications in Dialysis Patients 1 March 1979Volume 90, Issue 3Page: 351-353KeywordsAbdominal painAcute pancreatitisCreatinineRenal diseases Issue Published: 1 March 1979 PDF downloadLoading ...