Invasive Dental Treatment and Risk for Vascular Events
Authors: Caroline Minassian, Liam Smeeth, Francesco D'Aiuto, Aroon D. Hingorani
Journal: Annals of Internal Medicine (2011)

Letters15 March 2011Invasive Dental Treatment and Risk for Vascular EventsCaroline Minassian, MSc, Liam Smeeth, PhD, Francesco D'Aiuto, PhD, and Aroon D. Hingorani, PhDCaroline Minassian, MScFrom London School of Hygiene and Tropical Medicine, London WC1E 7HT, United Kingdom; University College London Eastman Dental Institute, London WC1X 8LD, United Kingdom; and University College London, London WC1E 6BT, United Kingdom.Search for more papers by this author, Liam Smeeth, PhDFrom London School of Hygiene and Tropical Medicine, London WC1E 7HT, United Kingdom; University College London Eastman Dental Institute, London WC1X 8LD, United Kingdom; and University College London, London WC1E 6BT, United Kingdom.Search for more papers by this author, Francesco D'Aiuto, PhDFrom London School of Hygiene and Tropical Medicine, London WC1E 7HT, United Kingdom; University College London Eastman Dental Institute, London WC1X 8LD, United Kingdom; and University College London, London WC1E 6BT, United Kingdom.Search for more papers by this author, and Aroon D. Hingorani, PhDFrom London School of Hygiene and Tropical Medicine, London WC1E 7HT, United Kingdom; University College London Eastman Dental Institute, London WC1X 8LD, United Kingdom; and University College London, London WC1E 6BT, United Kingdom.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-154-6-201103150-00016 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:We are pleased that our study on the risk for vascular events after invasive dental treatment has generated interest. However, it is clear that some readers poorly understood this study, and we would like to address some of the points that they raised.Dr. Janket and colleagues may have misinterpreted the SCCS method that we used as a collection of case reports with no comparison group. We agree that such uncontrolled case series could be prone to confounding and are unsuitable for investigating causal relationships. Readers should not confuse this method with the SCCS method that we used, ...References1. Smeeth L, Cook C, Thomas S, Hall AJ, Hubbard R, Vallance P. Risk of deep vein thrombosis and pulmonary embolism after acute infection in a community setting. Lancet. 2006;367:1075-9. [PMID: 16581406] CrossrefMedlineGoogle Scholar2. Taylor B, Miller E, Farrington CP, Petropoulos MC, Favot-Mayaud I, Li J, Waight PA. Autism and measles, mumps, and rubella vaccine: no epidemiological evidence for a causal association. Lancet. 1999;353:2026-9. [PMID: 10376617] CrossrefMedlineGoogle Scholar3. Hubbard R, Farrington P, Smith C, Smeeth L, Tattersfield A. Exposure to tricyclic and selective serotonin reuptake inhibitor antidepressants and the risk of hip fracture. Am J Epidemiol. 2003;1581:77-84. CrossrefGoogle Scholar Author, Article, and Disclosure InformationAuthors: Caroline Minassian, MSc; Liam Smeeth, PhD; Francesco D'Aiuto, PhD; Aroon D. Hingorani, PhDAffiliations: From London School of Hygiene and Tropical Medicine, London WC1E 7HT, United Kingdom; University College London Eastman Dental Institute, London WC1X 8LD, United Kingdom; and University College London, London WC1E 6BT, United Kingdom.Disclosures: Disclosures can also be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M10-0574. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoInvasive Dental Treatment and Risk for Vascular Events Caroline Minassian , Francesco D'Aiuto , Aroon D. Hingorani , and Liam Smeeth Invasive Dental Treatment and Risk for Vascular Events Sok-Ja Janket , Kamal Jethwani , and Jukka H. Meurman Invasive Dental Treatment and Risk for Vascular Events Joseph D. Matthews Metrics 15 March 2011Volume 154, Issue 6Page: 442KeywordsDisclosureDrugsEpidemiologyFactor analysisFearMedical risk factorsMyocardial infarctionObservational studiesRespiratory system proceduresUpper respiratory tract infections ePublished: 15 March 2011 Issue Published: 15 March 2011 Copyright & PermissionsCopyright © 2011 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...