Vitamin and Mineral Supplements in the Primary Prevention of Cardiovascular Disease and Cancer
Authors: Mark J. Bolland, Andrew Grey, Ian R. Reid
Journal: Annals of Internal Medicine (2014)

Letters6 May 2014Vitamin and Mineral Supplements in the Primary Prevention of Cardiovascular Disease and CancerMark J. Bolland, MBChB, PhD, Andrew Grey, MD, and Ian R. Reid, MDMark J. Bolland, MBChB, PhDFrom University of Auckland, Auckland, New Zealand., Andrew Grey, MDFrom University of Auckland, Auckland, New Zealand., and Ian R. Reid, MDFrom University of Auckland, Auckland, New Zealand.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/L14-5009-4 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Fortmann and colleagues (1) identified 5 randomized, controlled trials (RCTs) of calcium or vitamin D supplements and cardiovascular disease and cancer. Data were available on all-cause mortality for 3 RCTs of calcium, 1 RCT of vitamin D, and 1 RCT of calcium and vitamin D; cardiovascular disease incidence for 1 RCT of calcium, 2 RCTs of vitamin D, and 1 RCT of calcium and vitamin D; and cancer incidence for 3 RCTs of calcium, 2 RCTs of vitamin D, and 1 RCT of calcium and vitamin D.In previous systematic reviews of calcium supplementation, we identified 8 ...References1. Fortmann SP, Burda BU, Senger CA, Lin JS, Whitlock EP. Vitamin and mineral supplements in the primary prevention of cardiovascular disease and cancer: an updated systematic evidence review for the U.S. Preventive Services Task Force. Ann Intern Med. 2013;159:824-34. [PMID: 24217421] LinkGoogle Scholar2. Bolland MJ, Avenell A, Baron JA, Grey A, MacLennan GS, Gamble GD, et al. Effect of calcium supplements on risk of myocardial infarction and cardiovascular events: meta-analysis. BMJ. 2010;341:c3691. [PMID: 20671013] CrossrefMedlineGoogle Scholar3. Bristow SM, Bolland MJ, MacLennan GS, Avenell A, Grey A, Gamble GD, et al. Calcium supplements and cancer risk: a meta-analysis of randomised controlled trials. Br J Nutr. 2013;110:1384-93. [PMID: 23601861] CrossrefMedlineGoogle Scholar4. Elamin MB, Abu Elnour NO, Elamin KB, Fatourechi MM, Alkatib AA, Almandoz JP, et al. Vitamin D and cardiovascular outcomes: a systematic review and meta-analysis. J Clin Endocrinol Metab. 2011;96:1931-42. [PMID: 21677037] CrossrefMedlineGoogle Scholar5. Higgins JPT, Green S, eds. Cochrane Handbook for Systematic Reviews of Interventions, Version 5.1.0. The Cochrane Collaboration, 2011. Accessed at www.cochrane-handbook.org on 28 March 2014. Google Scholar Author, Article, and Disclosure InformationAffiliations: From University of Auckland, Auckland, New Zealand.Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L14-0082. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoVitamin and Mineral Supplements in the Primary Prevention of Cardiovascular Disease and Cancer: An Updated Systematic Evidence Review for the U.S. Preventive Services Task Force Stephen P. Fortmann , Brittany U. Burda , Caitlyn A. Senger , Jennifer S. Lin , and Evelyn P. Whitlock Vitamin and Mineral Supplements in the Primary Prevention of Cardiovascular Disease and Cancer Sebastian J. Padayatty and Mark Levine Vitamin and Mineral Supplements in the Primary Prevention of Cardiovascular Disease and Cancer Yosef Dror and Felicia Stern Vitamin and Mineral Supplements in the Primary Prevention of Cardiovascular Disease and Cancer Harri Hemilä Vitamin and Mineral Supplements in the Primary Prevention of Cardiovascular Disease and Cancer Stephen P. Fortmann , Evelyn P. Whitlock , and Brittany U. Burda Vitamin and Mineral Supplements in the Primary Prevention of Cardiovascular Disease and Cancer Harri Hemilä Vitamin and Mineral Supplements in the Primary Prevention of Cardiovascular Disease and Cancer Yosef Dror and Felicia Stern Vitamin and Mineral Supplements in the Primary Prevention of Cardiovascular Disease and Cancer Stephen P. Fortmann , Evelyn P. Whitlock , and Brittany U. Burda Vitamin and Mineral Supplements in the Primary Prevention of Cardiovascular Disease and Cancer Sebastian J. Padayatty and Mark Levine Metrics Cited byDietary patterns, BCMO1 polymorphisms, and primary lung cancer risk in a Han Chinese population: a case-control study in Southeast ChinaUse of vitamin and mineral supplements and related variables among university students in Seoul 6 May 2014Volume 160, Issue 9Page: 655-656KeywordsAdverse eventsCalciumCancer preventionCardiovascular diseasesDisclosureMyocardial infarctionSystematic reviewsVitamin D ePublished: 6 May 2014 Issue Published: 6 May 2014 Copyright & PermissionsCopyright © 2014 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...