Smoking Cessation and the Risk for Type 2 Diabetes Mellitus
Authors: Roy C. Ziegelstein
Journal: Annals of Internal Medicine (2010)

Letters1 June 2010Smoking Cessation and the Risk for Type 2 Diabetes MellitusRoy C. Ziegelstein, MDRoy C. Ziegelstein, MDFrom Johns Hopkins Bayview Medical Center, Baltimore, MD 21224.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-152-11-201006010-00018 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Yeh and colleagues (1) report that smoking cessation may increase the risk for type 2 diabetes mellitus. This may not be that surprising, given the well-known relationship between smoking cessation and weight gain, which has been exploited by cigarette manufacturers for many years (2). Yeh and colleagues (1) found that weight gain did, in fact, explain some of the excess risk for incident diabetes in smokers who quit. However, the mechanism of the increased risk for type 2 diabetes in these ex-smokers is undoubtedly more complex. Of note, smoking cessation can trigger a major depressive episode (3, ...References1. Yeh HC, Duncan BB, Schmidt MI, Wang NY, Brancati FL. Smoking, smoking cessation, and risk for type 2 diabetes mellitus: a cohort study. Ann Intern Med. 2010;152:10-7. [PMID: 20048267] LinkGoogle Scholar2. Boyd TC, Boyd CJ, Greenlee TB. A means to an end: slim hopes and cigarette advertising. Health Promot Pract. 2003;4:266-77. [PMID: 14610997] CrossrefMedlineGoogle Scholar3. Covey LS, Glassman AH, Stetner F. Major depression following smoking cessation. Am J Psychiatry. 1997;154:263-5. [PMID: 9016279] CrossrefMedlineGoogle Scholar4. Glassman AH, Covey LS, Stetner F, Rivelli S. Smoking cessation and the course of major depression: a follow-up study. Lancet. 2001;357:1929-32. [PMID: 11425414] CrossrefMedlineGoogle Scholar5. Wagner J, Allen , Swalley LM, Melkus GD, Whittemore R. Depression, depression treatment, and insulin sensitivity in adults at risk for type 2 diabetes. Diabetes Res Clin Pract. 2009;86:96-103. [PMID: 19720419] CrossrefMedlineGoogle Scholar6. Irwin MR, Miller AH. Depressive disorders and immunity: 20 years of progress and discovery. Brain Behav Immun. 2007;21:374-83. [PMID: 17360153] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Johns Hopkins Bayview Medical Center, Baltimore, MD 21224.Disclosures: None disclosed. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoSmoking, Smoking Cessation, and Risk for Type 2 Diabetes Mellitus Hsin-Chieh Yeh , Bruce B. Duncan , Maria Inês Schmidt , Nae-Yuh Wang , and Frederick L. Brancati Smoking Cessation and the Risk for Type 2 Diabetes Mellitus Altan Onat Smoking Cessation and the Risk for Type 2 Diabetes Mellitus Richard L. Shriner , Noni A. Graham , and Mark S. Gold Smoking Cessation and the Risk for Type 2 Diabetes Mellitus Hsin-Chieh Yeh and Frederick L. Brancati Metrics Cited ByRelationship of cardiometabolic parameters in non-smokers, current smokers, and quitters in diabetes: a systematic review and meta-analysisTesting a prediabetes screening approach for a Latin American population in Vancouver, Canada 1 June 2010Volume 152, Issue 11Page: 754KeywordsConflicts of interestDietInflammationInsulin resistanceMedical risk factorsRisk managementSmoking habitsType 2 diabetesWeight gain ePublished: 1 June 2010 Issue Published: 1 June 2010 CopyrightCopyright © 2010 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...