Renal Vasculitis in a Nonfatal Case of Henoch-Schönlein Purpura
Authors: WILLIAM F. FALLS
Journal: Annals of Internal Medicine (1966)

Case Studies1 June 1966Renal Vasculitis in a Nonfatal Case of Henoch-Schönlein PurpuraWILLIAM F. FALLS JR., M.D., KENNETH L. FORD, M.D., CHARLES T. ASHWORTH, M.D., NORMAN W. CARTER, M.D.WILLIAM F. FALLS JR., M.D.Search for more papers by this author, KENNETH L. FORD, M.D.Search for more papers by this author, CHARLES T. ASHWORTH, M.D.Search for more papers by this author, NORMAN W. CARTER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-64-6-1276 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptHenoch-Schönlein purpura is a well-defined clinical entity characterized by a typical skin eruption, polyarthralgia, abdominal pain, occasional bleeding from the bowel, and not infrequently hematuria (1, 2). Most authors agree that evidence of nephritis, as manifested by red cells and casts in the urine sediment or proteinuria, occurs in 40 to 60% of cases during some phase of the disease (3-11). Focal glomerulonephritis has been described repeatedly in renal biopsies from this disease (5, 10, 12-15), but vasculitis, although always present in cutaneous lesions, has been reported previously in the kidney only in autopsy material (16, 17). The present case...References1. DAMESHEK W: Acute vascular purpura: an immuno-vascular disorder. Blood 8: 382, 1953. CrossrefMedlineGoogle Scholar2. ACKROYD JF: Allergic purpura, including purpura due to foods, drugs and infections. Amer. J. Med. 14: 605, 1953. CrossrefMedlineGoogle Scholar3. GAIRDNER D: The Schönlein-Henoch syndrome (anaphylactoid purpura). Quart. J. Med. 17: 95, 1948. MedlineGoogle Scholar4. KREIDBERGDAMESHEKLATORRACO MBWR: Acute vascular (Schönlein-Henoch) purpura—an immunologic disease? New Eng. J. Med. 253: 1014, 1955. CrossrefMedlineGoogle Scholar5. BERGSTRANDBERGSTRANDBUCHT ACGH: Kidney lesions associated with anaphylactoid purpura in children. Acta Paediat. (Stockholm) 49: 57, 1960. CrossrefMedlineGoogle Scholar6. BYWATERSISDALEKEMPTON EGIJJ: Schönlein-Henoch purpura. Quart. J. Med. 26: 161, 1957. MedlineGoogle Scholar7. DERHAMROGERSON RJMM: The Schönlein-Henoch syndrome with particular reference to renal sequellae. Arch. Dis. Child. 31: 364, 1956. CrossrefMedlineGoogle Scholar8. OLIVERBARNETT TKHL: The incidence and prognosis of nephritis associated with anaphylactoid (Schönlein-Henoch) purpura in children (abstract). Amer. J. Dis. Child. 90: 544, 1955. Google Scholar9. PHILPOTT MG: The Schönlein-Henoch syndrome in childhood with particular reference to the occurrence of nephritis. Arch. Dis. Child. 27: 480, 1952. CrossrefMedlineGoogle Scholar10. VERNIERFARQUHARBRUNSONGOOD RLMGJGRA: Chronic renal disease in children. Amer. J. Dis. Child. 96: 306, 1958. CrossrefMedlineGoogle Scholar11. WEDGWOODKLAUS RJMH: Anaphylactoid purpura (Schönlein-Henoch syndrome): a long-term follow-up study with special reference to renal involvement. Pediatrics 16: 196, 1955. MedlineGoogle Scholar12. VERNIERWORTHENPETERSONCOLLEGOOD RLHGRDERA: Anaphylactoid purpura. I. Pathology of the skin and kidney and frequency of streptococcal infection. Pediatrics 27: 181, 1961. MedlineGoogle Scholar13. DODGEDAESCHNERBRENNANROSENBERGTRAVISHOPPS WFCWJCHSLBHC: Percutaneous renal biopsy in children. II. Acute glomerulonephritis, chronic glomerulonephritis, and nephritis of anaphylactoid purpura. Pediatrics 30: 297, 1962. MedlineGoogle Scholar14. HEPTINSTALL RH: The kidney in Schönlein-Henoch syndrome, in Recent Advances in Pathology, 7th ed. Edited by HARRISON, C. V. Little, Brown and Co., Boston, 1960, pp. 87-92. Google Scholar15. HEPTINSTALLJOEKES RHAM: Renal biopsy. Proc. Roy. Soc. Med. 52: 211, 1959. CrossrefMedlineGoogle Scholar16. LECUTIER MA: A case of the Schönlein-Henoch syndrome with myocardial necrosis. J. Clin. Path. 5: 336, 1952. CrossrefMedlineGoogle Scholar17. LEVITTBURBANK LMB: Glomerulonephritis as a complication of the Schönlein-Henoch syndrome. New Eng. J. Med. 284: 530, 1953. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: From the Departments of Internal Medicine and Pathology, The University of Texas Southwestern Medical School, Dallas, Tex.This study was supported in part by grant HE-0876, U. S. Public Health Service, Washington, D. C.Dr. Falls is a trainee under grant 5 T1 AM 5028, U. S. Public Health Service, Washington, D. C., and Dr. Ford is a trainee under research training grant GM-227, U. S. Public Health Service, Washington, D. C.Requests for reprints should be addressed to Norman W. Carter, M.D., University of Texas Southwestern Medical School, Department of Internal Medicine, Dallas, Tex. 75235. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited BySchönlein-Henoch syndrome in adults and childrenHenoch-Schönlein anaphylactoid purpura nephropathy: Electron microscopic lesions mimicking acute poststreptococcal nephritisGLOMERULAR LESIONS IN ADULTS WITH THE SCHÖNLEIN-HENOCH SYNDROMERenal manifestations of the Henoch-Schoenlein syndrome in adultsHENOCH-SCHONLEIN PURPURA WITH PARTICULAR REFERENCE TO THE PROGNOSIS OF THE RENAL LESIONAnaphylactoid purpuraRecent Advances in the Rheumatic DiseasesEPHRAIM P. ENGLEMAN, M.D., F.A.C.P., MARTIN A. SHEARN, M.D., F.A.C.P. 1 June 1966Volume 64, Issue 6Page: 1276-1280KeywordsGlomerulonephritisHemorrhageLesionsMedical servicesNephritisProteinuriaRenal diseasesResearch grantsUrineVasculitis Issue Published: 1 June 1966 PDF DownloadLoading ...