The Horace Dobell Lecture on the Life-History of Saprophytic and Parasitic Bacteria and their Mutual Relation: Delivered before the Royal College of Physicians of London on November 22nd, 1904
Authors: E. Klein
Journal: BMJ (1904)

HORACE DOBELL LEOTURE. [DEe.3, I91 secondary deposits in 'that organ.In one case I was able to remove as much as half a pound of the liver with success.Cancer of the Lip.Even if the pre-cancerous stage has passed, a free removal of the disease at an early stage and while it isstill local enables a very.good prognosis to be-given.Mr. Butlin's analysis of tx4 cases of epithelioma of the lip from the Gottingen Clinic showed that 53 per cent. of cases were alive and well or had died of other diseases more than three years after removal, and ,of these twelve had lived for at least twelve years and one for eighteen years after operation.Dr. Lo ?s analyzed the returns of bthe Tubingen Hospital for.1843.tow885 and found that the cures averaged 51 per cent., but in the years from i885 to i898 they had increased to 66 percent.Mr. Marmaduke Sheild has told me of one patient from whom he remotved an epithelioma of the lip with submental glands twenty years ago.The patient died last yearat the age of gi, without recurrence.Cancer of the Penis.In epithelioma of the penis amputation yields a cure in lone-third of the cases operated on.Mr. Butlin gives cases under his own, observation living and well from six to ten years later, and of somo,colleeted cases well for nea,rly twenty years.Mr. Sheild has told me of 4 cases of his well after.nine, seven, six and a half, and three years respectively, and I can point to one case well after fifteen years and to others at lesser periods.Cancer of the Uterus.Much may be done to prevent this dread disease by careful eurgical treatment, and that without risk.Even when the pre-cancerous stage is passed, if women could be educated to the fact that were they to seek advice earlier,, and, in, fact, whenever an abnormal sanguineous discharge appears, apart from a menstrual period, in a very large percentage of cases the cancer would be recognized in its incipient condition when the disease is local, and removal could be carried out and cure effected.In order to prove these statements I wrote to the medioal attendants of all the private patients on whom I had operated, and was very much gratified to find many not only living but in r)bust health, from whom I had removed cancer of the uterus by complete or partial hysterectomy years ago.I made an attempt to get the statistics of my hospital patients, but found4 it absolutely impracticable, as nearly all the letters were returned on account of change of address, so that the etttisties are limited to private patients; and as these cases were nearly all seen at an early stage of the disease, and the growtht was examined microscopically after removal, I think they form a valuable addition to the statistics of uterine cancer, for every case can be verified.They are 27 in number-zr total hysterectomies without a death, of which a is alive and well 8j years after operation.a ,, ,,a are ,, . , 5*, 2 are ,, ,,From 4 no answers were received.s4 very free supravaginal amputations of the cervix without a death, of which a is alive and well 'i4 years after operation.Xf ,, ,, I0 § ,. .. .X , I0 , 9 9 9 E lived for 5 years and died of heart disease without recurrence of cancer.From 2 no answer was received.l lived 4 years, and recurrence took place.e; lived I year or less, and recurrence.tookplace.Mr.