Corticosteroid-Induced Pancreatitis
Authors: David M. Felig
Journal: Annals of Internal Medicine (1996)

Letters1 June 1996Corticosteroid-Induced PancreatitisDavid M. Felig, MD and Mark Topazian, MDDavid M. Felig, MDYale University School of Medicine; New Haven, CT 06510Search for more papers by this author and Mark Topazian, MDYale University School of Medicine; New Haven, CT 06510Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-124-11-199606010-00018 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Controversy surrounds the diagnosis of corticosteroid-induced pancreatitis. Despite many initial reports, subsequent reviews questioned whether corticosteroids caused pancreatitis in any of these cases [1, 2]. Only one report of corticosteroid-induced pancreatitis in which recurrence was shown with rechallenge has been published [3]. We report a second such case.A 51-year-old man with the acquired immunodeficiency syndrome (AIDS) had an episode of pancreatitis in March 1993 attributed to didanosine treatment. The pancreatitis resolved after didanosine therapy was discontinued. Ultrasonography of the abdomen at that time showed no gallstones or sludge. The patient had normal serum albumin, calcium, and ...References1. Steinberg WM, Lewis JH. Steroid-induced pancreatitis: does it really exist? Gastroenterology. 1981; 81:799-808. Google Scholar2. Kaplan MH, Dreiling DA. Steroids revisited. II. Was cortisone responsible for the pancreatitis? Am J Gastroenterol. 1977; 67:141-7. Google Scholar3. Levine RA, McGuire RF. Corticosteroid-induced pancreatitis: a case report demonstrating recurrence with rechallenge. Am J Gastroenterol. 1988; 83:1161-4. Google Scholar4. Murthy UK, DeGregorio F, Oates RP, Blair DC. Hyperamylasemia in patients with the acquired immunodeficiency syndrome. Am J Gastroenterol. 1992; 87:332-6. Google Scholar5. Nelson MR, Erskine D, Hawkins DA, Gazzard BG. Treatment with corticosteroids—a risk factor for the development of clinical cytomegalovirus disease in AIDS. AIDS. 1993; 7:375-8. Google Scholar Author, Article, and Disclosure InformationAffiliations: Yale University School of Medicine; New Haven, CT 06510 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDrug induced pancreatitis: A systematic review of case reports to determine potential drug associationsAnalysis of the Association of Administration of various glucocorticoids with development of acute pancreatitis using US Food and Drug Administration adverse event reporting system (FAERS)Drug-Induced Acute Pancreatitis in AdultsIntravenous methylprednisolone induced acute pancreatitisA sudden onset of diabetic ketoacidosis and acute pancreatitis after introduction of mizoribine therapy in a patient with rheumatoid arthritisCronkhite-Canada syndrome presenting as recurrent severe acute pancreatitisAcute pancreatitis in paediatric systemic lupus erythematosusAcute pancreatitis and exacerbation of hepatitis B following reduced dose of prednisoloneAcute pancreatitis in human immunodeficiency virus–infected patients: a reviewPeri-operative steroid supplementationCorticotrophins, corticosteroids, and prostaglandinsAcute PancreatitisDexamethasone/prednisone 1 June 1996Volume 124, Issue 11Page: 1016KeywordsAIDSCorticosteroid therapyIdiopathic thrombocytopenic purpuraLipasesOpportunistic infectionsPancreatitisSerum albuminSludgeSteroid therapyUltrasound imaging Issue Published: 1 June 1996 Copyright & PermissionsCopyright © 1996 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...