Acute Respiratory Distress During Sclerotherapy for Esophageal Varices
Authors: ROBERTO MUSSO
Journal: Annals of Internal Medicine (1987)

Letters and Corrections1 April 1987Acute Respiratory Distress During Sclerotherapy for Esophageal VaricesROBERTO MUSSO, M.D., ROSARIO GIUSTOLISI, M.D., ELIO CACCIOLA, M.D.ROBERTO MUSSO, M.D.Search for more papers by this author, ROSARIO GIUSTOLISI, M.D.Search for more papers by this author, ELIO CACCIOLA, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-106-4-640_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Connors and coworkers (1) report that the adult respiratory distress syndrome, which may occur after endoscopic variceal sclerotherapy using sodium morrhuate, was not dependent on direct vascular injury from the sclerosing agent. They, therefore, suggest that some other cause is to be considered.We report that one cause in the development of the syndrome might be a direct activation of the contact system in the early phase of blood coagulation during or after sclerotherapy with sodium morrhuate. In fact, the contact system activation is a biological process closely linked to kinins and complement system activation, which in...References1. CONNORSBACONMIRON ABS. Sodium morrhuate delivery to the lung during endoscopic variceal sclerotherapy. Ann Intern Med. 1986;105:539-42. LinkGoogle Scholar2. NEEDLEMANHOAK SJ. Platelets and leukocytes in thrombosis. In: COLMAN RW, HIRSH J, MARDER VJ, SALZMAN EW, eds. Hemostasis and Thrombosis. Philadelphia: J. B. Lippincott; 1982:716-25. Google Scholar3. CACCIOLAGIUSTOLISIMUSSO ERR. Activation of contact phase of blood coagulation can be induced by the sclerosing agent polidocanol: possible additional mechanism of adverse reaction during sclerotherapy. J Lab Clin Med. 1987. (In press.) MedlineGoogle Scholar4. BENNETTOGSTON BD. Role of complement, coagulation, fibrinolysis and kinins in normal haemostasis and disease. In: BLOOM AL, THOMAS DP, eds. Haemostasis and Thrombosis. Edinburgh: Churchill Livingstone; 1981:236-51. Google Scholar5. STRONCEKHUTTONSILVISVERCELLOTTIJACOBHAMMERSCHMIDT DSSGHD. Sodium morrhuate stimulates granulocytes and damages erythrocytes and endothelial cells: probable mechanism of an adverse reaction during sclerotherapy. J Lab Clin Med. 1985;106:498-04. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: ROBERTO MUSSO, M.D.; ROSARIO GIUSTOLISI, M.D.; ELIO CACCIOLA, M.D.Affiliations: Institute of Medical Semeiotics and Hematology Department of Hemostasis Physiopathology University of Catania Italy PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byComplications of Upper Gastrointestinal Endoscopy and Their ManagementPleuropulmonary Complications of Endoscopic Variceal Sclerotherapy 1 April 1987Volume 106, Issue 4Page: 640-640KeywordsAcute respiratory distress syndromeBlood coagulationComplement activationComplement systemSodium ePublished: 1 December 2008 Issue Published: 1 April 1987 PDF downloadLoading ...