Diagnostic Workup of AIDS-associated Diarrhea
Authors: Gabor P. Kandel
Journal: Annals of Internal Medicine (1992)

Letters15 August 1992Diagnostic Workup of AIDS-associated DiarrheaGabor P. Kandel, MDGabor P. Kandel, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-117-4-346 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editors:As a practicing gastroenterologist in an urban center, I am grateful for the authoritative review by Smith and colleagues (1) on gastrointestinal infections in the acquired immunodeficiency syndrome (AIDS). I am puzzled, however, by their unqualified enthusiasm for endoscopy in the workup of diarrhea in these patients. The authors mention that in the National Institutes of Health (NIH) series, 45% of these patients had cytomegalovirus (2), the most frequent pathogen found by colonoscopy but not detectable by stool analysis or sigmoidoscopy. My experience is closer to that reported by Connolly and colleagues (3, 4), where cytomegalovirus colitis...References1. SmithQuinnStroberJanoffMasure PTWEH. Gastrointestinal infections in AIDS. Ann Intern Med. 1991;116:63-77. LinkGoogle Scholar2. SmithLaneGillManischewitzQuinanFauci PHVJGA. Intestinal infections in patients with acquired immunodeficiency syndrome (AIDS). Ann Intern Med. 1988;108:328-33. LinkGoogle Scholar3. ConnollyShansonHawkinsHarcourt WebesterGazzard GDDJB. Non-cryptosporidial diarrhoea in human immunodeficiency virus (HIV) infected patients. Gut. 1989;30:195-200. CrossrefMedlineGoogle Scholar4. ConnollyForbesGazzard GAB. Investigation of seemingly pathogen-negative diarrhoea in patients infected with HIVI. Gut. 1990;31:886-9. CrossrefMedlineGoogle Scholar5. LaughonDruckmanVernonQuinnPolkModlin BDATBJ. Prevalence of enteric pathogens in homosexual men with and without acquired immunodeficiency syndrome. Gastroenterology. 1988;94:984-93. CrossrefMedlineGoogle Scholar1. SmithQuinnStroberJanoffMasur PTWEH. Gastrointestinal infections in AIDS. Ann Intern Med. 1992;116:63-77. LinkGoogle Scholar1. SmithQuinnStroberJanoffMasur PTWEH. Gastrointestinal infections in AIDS. Ann Intern Med. 1992;116:63-77. LinkGoogle Scholar2. SmithLaneGillManischewitzQuinnanFauci PHVJGA. Intestinal infections in patients with the acquired immunodeficiency syndrome (AIDS): etiology and therapy. Ann Intern Med. 1988;102:612-22. Google Scholar3. ConnollyShansonHawkinsWebsterGazzard GDDJB. Non-cryptosporidial diarrhea in human immunodeficiency virus (HIV) infected patients. Gut. 1989;30:195-200. CrossrefMedlineGoogle Scholar4. ConnollyForbesGazzard GAB. Investigation of seemingly pathogen-negative diarrhea in patients infected with HIV-1. Gut. 1990;31:886-9. CrossrefMedlineGoogle Scholar5. Kotler D. Gastrointestinal and nutritional manifestations of the acquired immunodeficiency syndrome. New York: Raven Press; 1991. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: Gabor P. Kandel, MDAffiliations: The Wellesley Hospital Toronto, Ontario M4Y 1J3 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySynthesis of C1 ‐Symmetric Tripod Ligands Containing a P,P,N Donor Set − η 2 ‐Coordination in d 8 ‐Metal Complexes 15 August 1992Volume 117, Issue 4Page: 346-347KeywordsAIDSColitisColonoscopyDiarrheaEndoscopyGastrointestinal infectionsPathogens ePublished: 1 December 2008 Issue Published: 15 August 1992 PDF downloadLoading ...