Severe Sinus Node Dysfunction in Obstructive Jaundice
Authors: TALI T. BASHOUR
Journal: Annals of Internal Medicine (1985)

Brief Reports1 September 1985Severe Sinus Node Dysfunction in Obstructive JaundiceTALI T. BASHOUR, M.D., CHARLES ANTONINI Sr., M.D., JOHN FISHER, M.D.TALI T. BASHOUR, M.D., CHARLES ANTONINI Sr., M.D., JOHN FISHER, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-103-3-384 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSinus bradycardia has been linked to obstructive jaundice, among other metabolic, systemic, and central nervous conditions (1, 2). Conclusive evidence of sinus node dysfunction in association with biliary obstruction has not to our knowledge been presented. We report the case of a patient with gall bladder and bile duct malignancy who, as obstruction progressed, had cardiac arrest in asystole. He later had prolonged episodes of sinus pause complicated by escape atrial, junctional, or ventricular arrythmias. These arrythmias have disappeared and a markedly prolonged sinus node recovery time returned to normal after reduction of bilirubin levels by drainage of the bile...References1. BRAUNWALD E. Heart Disease. Philadelphia: W.B. Saunders Company; 1984:690. Google Scholar2. SONGSEGALHODKINSONKEW EIJM. Sinus bradycardia in obstructive jaundice—correlation with total serum bile acid concentrations. S Afr Med J. 1983;64:548-51. MedlineGoogle Scholar3. BASHOURKABBANIBREWSTERWALDHANNACHENG TSHSET. Sinus node dysfunction during coronary vasospastic angina. Am Heart J. 1984;108:1056-9. CrossrefMedlineGoogle Scholar4. PICKLANGENDORF AR. Interpretation of Complex Arrhythmias. Philadelphia: Lea and Febiger; 1979;127. Google Scholar5. RASMUSSENHAUNGSKAGEN VSR. Cerebral attacks due to excessive vagal tone in health trained persons: a clinical and electrophysiologic study. Acta Med Scand. 1978;204:401-5. CrossrefMedlineGoogle Scholar6. WALTERCRAWLEYDORNEY PIE. Carotid sinus hypersensitivity and syncope. Am J Cardiol. 1978;42:396-403. CrossrefMedlineGoogle Scholar7. GUILLEMINAULTPOOLMOTTAGILLIS CPJA. Sinus arrest during REM sleep in young adults. N Engl J Med. 1984;311:1006-10. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: TALI T. BASHOUR, M.D.; CHARLES ANTONINISr., M.D.; JOHN FISHER, M.D.Affiliations: Seton Medical Center Daly City the University of California School of Medicine San Francisco, California PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byCardiovascular dysfunction in liver diseases: pediatric perspectivesTransient sinus bradycardia caused by hepatitis A virus: a case reportSix seconds to P wave! Recovered without permanent pacemaker – An enlightening storyAssociation between cardiac dysfunction, arrhythmias and chronic liver diseases: A narrative reviewBile acid excess induces cardiomyopathy and metabolic dysfunctions in the heartLinezolid-induced bradycardia: a case reportThe role of nitric oxide in bradycardia of rats with obstructive cholestasisSinus Node Suppression in Acute Strokes—Case ReportsCellular electrophysiologic effects of vertebrate digitalis-like substancesClassificaion of sinus node dysfunction 1 September 1985Volume 103, Issue 3Page: 384-385KeywordsArrhythmiaBileBile ductsBilirubinBladderBradycardiaHeart ePublished: 1 December 2008 Issue Published: 1 September 1985 PDF downloadLoading ...