Plasma Expanders and Bleeding
Authors: NEIL ABRAMSON
Journal: Annals of Internal Medicine (1988)

Letters and Corrections1 February 1988Plasma Expanders and BleedingNEIL ABRAMSON, M.D.NEIL ABRAMSON, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-108-2-307_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Plasma expanders are commonly used in emergency medical care in patients with hypotension. Recent letters (1, 2) have recounted clinical bleeding in neurosurgical patients. Hydroxyethyl starch is a plasma expander that greatly increased the bleeding diathesis in a patient.A 52-year-old black man was hospitalized because of hemoptysis from a tuberculous lesion of the left upper lobe. He also had a history of alcohol abuse and evidence of liver disease. Spur cell hemolytic anemia was shown by reticulocytosis, target cells, spur cells, splenomegaly, negative Coombs test, and hypohaptoglobinemia. Coagulation studies showed mild elevations in prothrombin and partial...References1. SYMINGTON B. Hetastarch and bleeding complications. Ann Intern Med. 1986;105:627-8. LinkGoogle Scholar2. DAMON L, ADAMS M, STRICKER R, and RIES C. Intracranial bleeding during treatment with hydroxyethyl starch. N Engl J Med. 1987;317:964-5. CrossrefMedlineGoogle Scholar3. STRAUSS R. Review of effects of hydroxyethyl starch on blood coagulation system. Transfusion. 1981;21:299-302. CrossrefMedlineGoogle Scholar4. STRAUSS R, STUMP D, and HENDRICKSON R. Hydroxyethyl starch accentuates von Willebrand's disease. Transfusion. 1985;25:235-7. CrossrefMedlineGoogle Scholar5. FARRALES F and BELCHER C. Effect of hydroxyethyl starch on platelet function following granulocyte collection using the continued flow-cell separater. Transfusion. 1977;17:635-7. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: NEIL ABRAMSON, M.D.Affiliations: Malone Cancer Institute Baptist Medical Center Jacksonville, FL 32207 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byRemplissage vasculaire et autres techniques de correction volémiqueComparison of two hydroxyethyl starch 200/0.5 formulations with regard to hemorheology, coagulation and elimination kineticsIntraoperative volume optimisationFluid Therapy and CoagulationResuscitation from hemorrhagic shock: Experimental model comparing normal saline, dextran, and hypertonic saline solutionsFluid therapy in sepsis with capillary leakageFluid therapy in sepsis with capillary leakageEffets des solutés de remplissage vasculaire sur l’hémostaseEfficacy of Plasma Substitutes for Volume TherapyBleeding Complications and Hydroxyethyl Starch: Strategies of PreventionHydroxyéthylamidons: effets sur l'hémostase2 Pharmacological characteristics of artificial colloidsPlasma SubstitutesHämodilution und Gerinnung 1 February 1988Volume 108, Issue 2 Page: 307-307 Keywords Alcoholism Blood plasma Hemolytic anemia Hemorrhage Hypotension Lesions Liver diseases Patients Splenomegaly Starches ePublished: 1 December 2008 Issue Published: 1 February 1988 PDF downloadLoading ...