Amyloidosis in Association with Neoplastic Disease
Authors: KENT G. KIMBALL
Journal: Annals of Internal Medicine (1961)

Article1 December 1961Amyloidosis in Association with Neoplastic DiseaseReport of an Unusual Case and Clinicopathological Experience at Memorial Center for Cancer and Allied Diseases during Eleven Years (1948-1958)KENT G. KIMBALL, M.D.KENT G. KIMBALL, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-55-6-958 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAmyloidosis is a disease of unknown etiology characterized by deposits in various tissues of a glycoprotein material immunologically related to normal gamma globulin (1). It occurs as localized amyloidosis, generalized "primary" amyloidosis without any predisposing disease, and generalized "secondary" amyloidosis with predisposing disease (2).Localized amyloidosis occurs in the respiratory tract, the bladder, urethra, skin, oral mucosa, and occasionally in squamous papillomas and basal cell carcinomas of the skin (2). Primary amyloidosis consists of amyloid of slightly different staining characteristics from those of the secondary variety. It involves primarily the liver, heart, and spleen, and to a lesser extent the...References1. OSSERMAN EF: Plasma cell myeloma. II. Clinical aspects (concluded). New Engl. J. Med. 261: 1006, 1959. CrossrefMedlineGoogle Scholar2. SYMMERS WS: Primary amyloidosis: a review. J. Clin. Path. 9: 187, 1956. CrossrefMedlineGoogle Scholar3. RUKAVINABLOCKJACKSONFALLSCAREYCURTIS JGWDCEHFJHAC: Primary systemic amyloidosis: review and experimental, genetic, and clinical study of 29 cases with particular emphasis on familial form. Medicine 35: 239, 1956. CrossrefMedlineGoogle Scholar4. DAHLIN DC: Secondary amyloidosis. Ann. Intern. Med. 31: 105, 1949. LinkGoogle Scholar5. CALKINSCOHEN EAS: Diagnosis of amyloidosis. Bull. Rheum. Dis. 10: 215, 1960. MedlineGoogle Scholar6. BERO GL: Amyloidosis: its clinical and pathologic manifestation, with a report of 12 cases. Ann. Intern. 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LEE, M.D., H. YAMAUCHI, M.D., JAMES HOPPER JR., M.D.A review of unusual systemic manifestations associated with carcinomaCase 76-1963Connective tissue disease associated with malignant neoplastic diseaseAmyloid Goiter Associated with the Nephrotic SyndromeCase 43-1962 1 December 1961Volume 55, Issue 6Page: 958-974KeywordsAmyloidosisDiarrheaEdemaHypoproteinemiaMultiple myelomaProteinuriaRespiratory systemSpleenStainingUrea ePublished: 1 December 2008 Issue Published: 1 December 1961 PDF downloadLoading ...