Follow-up of Sarin Poisoning in Matsumoto
Authors: Yoshiki Sekijima
Journal: Annals of Internal Medicine (1997)

Letters1 December 1997Follow-up of Sarin Poisoning in MatsumotoYoshiki Sekijima, MD, PhD, Hiroshi Morita, MD, PhD, and Nobuo Yanagisawa, MD, PhDYoshiki Sekijima, MD, PhDShinsu University School of Medicine; Matsumoto 390, Japan, Hiroshi Morita, MD, PhDShinsu University School of Medicine; Matsumoto 390, Japan, and Nobuo Yanagisawa, MD, PhDShinsu University School of Medicine; Matsumoto 390, JapanAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-127-11-199712010-00028 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:The sarin (isopropyl methyl phosphonofluoridate) attack in Matsumoto, Japan, killed 7 residents and poisoned approximately 500 others [1]. Although widespread health hazards occurred during the acute phase [1-3], there are few data on the sequelae of sarin exposure [4, 5]. To explore the long-term effects of sarin on humans, we conducted 1-year and 2-year follow-up health examinations of all victims who showed a decrease in serum cholinesterase (ChE) activity or miosis during the acute phase.One hundred forty-nine victims met these criteria and 85 (57.0%) had these examinations. We classified them into 3 groups according to the ...References1. Morita H, Yanagisawa N, Nakajima T, Shimizu M, Hirabayashi H, Okudera H, et al. Sarin poisoning in Matsumoto, Japan. Lancet. 1995; 346:209-3. Google Scholar2. Suzuki T, Morita H, Ono K, Maekawa K, Nagai R, Yazaki Y. Sarin poisoning in Tokyo subway [Letter]. Lancet. 1995; 345:980. Google Scholar3. Nozaki H, Alkawa N, Shinozawa Y, Hori S, Fujishima S, Takuma K, et al. Sarin poisoning in Tokyo subway [Letter]. Lancet. 1995; 345:980-1. Google Scholar4. Duffy FH, Burchfiel JL, Bartels PH, Gaon M, Sim VM. Long-term effects of an organophosphate upon the human electroencephalogram. Toxicol Appl Pharmacol. 1979; 47:161-76. Google Scholar5. Sekijima Y, Morita H, Shindo M, Okudera H, Shibata T, Yanagisawa N. [A case of severe poisoning in the sarin attack in Matsumoto. One-year follow-up of clinical findings, and laboratory data.] Rinshoshinkeigaku. 1995; 35:1241-5. Google Scholar Author, Article, and Disclosure InformationAffiliations: Shinsu University School of Medicine; Matsumoto 390, Japan PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByBbc3 Loss Enhances Survival and Protein Clearance in Neurons Exposed to the Organophosphate Pesticide ChlorpyrifosAcetylcholinesterase inhibitors (nerve agents) as weapons of mass destruction: History, mechanisms of action, and medical countermeasuresSarin attacks in Japan: acute and delayed health effects in survivorsNovichok: a murderous nerve agent attack in the UKComparing the Antiseizure and Neuroprotective Efficacy of LY293558, Diazepam, Caramiphen, and LY293558-Caramiphen Combination against Soman in a Rat Model Relevant to the Pediatric PopulationThe synthetic neuroactive steroid SGE-516 reduces status epilepticus and neuronal cell death in a rat model of soman intoxicationNerve AgentsLong-term neuropathological and behavioral impairments after exposure to nerve agentsChemical terrorism and nerve agentsNerve AgentsGeneral OverviewThe Tokyo Subway Sarin AttackAnimal Models That Best Reproduce the Clinical Manifestations of Human Intoxication with Organophosphorus CompoundsChemical terrorism and nerve agentsChemical TerrorismThe Tokyo Subway Sarin AttackChemical terrorism and nerve agentsGuidelines for Treating Cardiac Manifestations of Organophosphates Poisoning with Special Emphasis on Long QT and Torsades De PointesSarin experiences in Japan: Acute toxicity and long-term effectsToxicological assessments of Gulf War veteransPrehospital management of sarin nerve gas terrorism in urban settings: 10 years of progress after the Tokyo subway sarin attackThe Role of Oximes in the Treatment of Nerve Agent Poisoning in Civilian CasualtiesOrganic Phosphorus Compounds—Nerve AgentsEffects of Sarin on the Nervous System of Subway Workers Seven Years after the Tokyo Subway Sarin AttackAcute and chronic effects of sarin exposure from the Tokyo subway incidentAccidentes o atentados con armas químicas: bases para la atención sanitaria 1 December 1997Volume 127, Issue 11Page: 1042KeywordsArrhythmiaElectroencephalographyFeversHypoxiaNerves Issue Published: 1 December 1997 CopyrightCopyright © 1997 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...