tbuckley/cabot-search huggingface dataset:
TCT-370 Outcomes According to Sex Following Unprotected Left Main Stenting With Drug-Eluting Stents: The Milan Experience
Authors: Gill Buchanan, Alaide Chieffo, Chiara Bernelli, Alfonso Ielasi, Matteo Montorfano, Azeem Latib, Mauro Carlino, Filippo Figini, Irene Franzoni, Francesco Giannini, Alessandro Durante, Santo Ferrarello, Alfredo Castelli, Antonio Colombo
Journal: Journal of the American College of Cardiology (2012)
A Randomized Clinical Trial of the Insulin Pump vs Intensive Conventional Therapy in Diabetic Pregnancies
Authors: Donald R. Coustan
Journal: JAMA (1986)

Improved perinatal outcome is associated with the prevention of hyperglycemia during pregnancy in diabetic women. To determine whether the method of insulin administration influences the degree of diabetic control obtained, we randomized 22 pregnant diabetic women to intensive conventional insulin therapy (N=11) and insulin pump therapy (N=11). Frequent outpatient visits; home glucose monitoring, at least six times daily; and frequent telephone contact were offered to all subjects. Patients were hospitalized in the inpatient clinical research center each trimester for a 24-hour metabolic profile. There were no differences between the two treatment groups with respect to outpatient mean glucose levels, symptomatic hypoglycemia, or glycosylated hemoglobin levels, or with respect to inpatient mean glucose level, glycemic excursions, chemical hypoglycemia, or hyperglycemia. Excellent metabolic control was achieved with both treatment methods. (<i>JAMA</i>1986;255:631-636)
Health Care Rationing
Authors: M D Reagan
Journal: New England Journal of Medicine (1988)

With health care expenditures in the United States running close to 12 percent of the gross national product, it is certainly not surprising that many are calling for strong cost-containment measures. One of the most frequently mentioned approaches is rationing, which is becoming almost identical in meaning with cost containment in general.For example, a recent editorial in the Los Angeles Times stated that rationing "already is part of the American system for an increasing number of people" 1; more generally, Berliner calls the word "rationing" "a generic term subsuming all measures for limiting utilization."2 Were this only a matter . . .
Testing electromagnetic fields for potential carcinogenic activity: a critical review of animal models.
Authors: J McCann, R Kavet, C N Rafferty
Journal: Environmental Health Perspectives (1997)

In order to assess the potential of electromagnetic fields (EMF) to influence the process of carcinogenesis, it will be necessary to supplement epidemiological studies with controlled laboratory studies in animals. There are now a number of suitable assays available that focus on different histopathological forms of cancer and on different stages of carcinogenesis--induction, promotion, progression. In this review we discuss eight major systems in the context of this generalized carcinogenesis paradigm. Our aim is to bring together what is currently known about the biology of carcinogenesis in these systems in order to provide a context for evaluating EMF results as they become available. We also critically discuss EMF test results that have so far been obtained in the animal models reviewed. Most of the 19 completed studies identified were negative. However, suggestive positive results were reported in three promotion assays (in rat mammary gland, in rat liver, and in mouse skin), and in one multigeneration study in mice. Results in the rat liver assay and in the multigeneration study have only been reported in abstract form and cannot be adequately evaluated. Positive results reported in both the rat mammary gland and the mouse skin systems are of weak statistical significance and have not been independently replicated. However, it may be of interest that effects in both systems appear primarily to involve the progression stage of carcinogenesis. We suggest that more definitive conclusions as to the carcinogenic potential of EMF may require expanded test protocols that reinforce traditional carcinogenesis end points with biochemical or other parameters reflective of biological processes known to be associated with carcinogenesis in the different systems.
Noninvasive quantitation of myocardial infarction with technetium 99m pyrophosphate.
Authors: E H Botvinick, D Shames, H Lappin, J V Tyberg, R Townsend, W W Parmley
Journal: Circulation (1975)

We sought to quantitate infarct size using radioactive imaging techniques. Infarcts were created in closed chest dogs. Using a scintillation camera interfaced to a computer, infarct images were made in the anterior, left lateral, LAO, and RAO projections, 48 hours after infarction and 75 to 90 min following the intravenous injection of 15 mCi of Technetium 99m pyrophosphate (Tc-PYP). Images were computer enhanced and area was calibrated with a radioactive grid source of known dimensions. Image radioactivity was normalized for decay and dose corrected for body weight. Animals were sacrificed two hours following the injection Tc-PYP. Postmortem images were also computer enhanced and calibrated. Gross infarct area and weight were estimated and transmural biopsies were evaluated for Tc-PYP activity and analyzed for creatine phosphokinase (CPK) content. Contiguous biopsies were pathologically analyzed and graded. There was a negative correlation between tissue Tc-PYP activity and CPK content (r=0.89). Pathologic severity worsened with increased Tc-PYP activity and diminished CPK content. There was a good correlation between gross infarct area and image infarct area, both in vivo (r
Pulmonary Brucellosis on FDG PET/CT
Authors: Tao Zhang, Chunmei Wang, Ruilong Niu, Xuemei Wang
Journal: Clinical Nuclear Medicine (2013)

A 67-year-old man known with pulmonary nodule underwent FDG PET/CT scan for further evaluation. The images showed increased FDG activity in the pulmonary lesions and in the mediastinal and hilar lymph nodes without extrathoracic abnormality. Pulmonary brucellosis was subsequently diagnosed. The patient received anti-Brucella therapy and recovered promptly.
ALAS2 acts as a modifier gene in patients with congenital erythropoietic porphyria
Authors: Jordi To-Figueras, Sarah Ducamp, Jerome Clayton, Celia Badenas, Constance Delaby, Cecile Ged, Said Lyoumi, Laurent Gouya, Hubert de Verneuil, Carole Beaumont, Gloria C. Ferreira, Jean-Charles Deybach, Carmen Herrero, Herve Puy
Journal: Blood (2011)
Low molecular weight alkyl-polycation wrapped magnetite nanoparticle clusters as MRI probes for stem cell labeling and in vivo imaging
Authors: Gang Liu, Zhiyong Wang, Jian Lu, Chunchao Xia, Fabao Gao, Qiyong Gong, Bin Song, Xuna Zhao, Xintao Shuai, Xiaoyuan Chen, Hua Ai, Zhongwei Gu
Journal: Biomaterials (2010)
Reviews and Notes: Metabolism: Diabetes: Clinical Science in Practice
Authors: N. Wilson Rodger
Journal: Annals of Internal Medicine (1996)

Literature of Medicine15 May 1996Reviews and Notes: Metabolism: Diabetes: Clinical Science in PracticeN. Wilson Rodger, MD, FRCPCN. Wilson Rodger, MD, FRCPCSt. Josephs' Hospital, University of Western Ontario, London, Ontario, N6A 4V2, CanadaSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-124-10-199605150-00042 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail RDG Leslie and DC Robbins; eds. 478 pages. New York: Cambridge Univ Pr; 1995. $150.00. ISBN 0-521-45029-2. Order phone 800-221-4512.Increasingly prevalent in both of its major forms, diabetes mellitus is demanding attention in all corners of the world from most, if not all, of the biomedical sciences. The body of available information is enormous and evolving. The perspectives and demands of the readership are diverse. The editors of this book have correctly perceived that timely, scholarly, concise reviews are critical to the guidance and indeed to the survival of physicians in this environment.They have assembled a series of ... Author, Article, and Disclosure InformationAffiliations: St. Josephs' Hospital, University of Western Ontario, London, Ontario, N6A 4V2, Canada PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 15 May 1996Volume 124, Issue 10Page: 936KeywordsDiabetes mellitusGlucoseGlycationInsulinInsulin secretionPathogensProteinuriaTransplantationType 2 diabetesVascular diseases ePublished: 15 August 2000 Issue Published: 15 May 1996 Copyright & PermissionsCopyright © 1996 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Role of living liver donation in the United Kingdom
Authors: J. Neuberger
Journal: BMJ (2003)

Patients who need a new liver usually face a long wait. Some die before a suitable donor is found. Living liver donation is offered routinely in some countries. Should the United Kingdom follow suit? 

Liver transplantation has become an accepted form of treatment for patients with end stage liver disease and those with an unacceptable quality of life because of liver disease. Despite government initiatives to increase donor rates and surgical innovations to maximise the use of existing donor livers, the number of donor organs is insufficient to meet the existing demand. Living liver donation has the potential to help mitigate the deficit and is offered routinely in many countries in North America, Asia, and continental Europe. Living liver donation is not routinely available in the United Kingdom, although a few living transplant operations have been done led by Roger Williams and Nigel Heaton.1 We believe that living liver donation should be available on the NHS, although it should not be adopted without full public debate and agreement because of the risks to donors.

The United Kingdom has no reliable information on requirements for liver transplantation. Although we have data on the number accepted for transplantation,2 not everyone who might benefit from transplantation is referred.3 The rate of transplantation is relatively low compared with other European countries (11.6/million population compared with 19.3/million in France and 24.3/million in Spain). However, we do not know the requirement for transplantation because the burden of liver disease in these countries may differ. Donor rates also vary between countries, but the proportion of potential donors who are offered for transplantation is not known. The number of patients dying from liver disease in England is increasing.4

   ![][1] 

Liver transplant operation

Credit: J L MARTRA/PUBLIPHOTO DIFFUSION/SPL

To be accepted on the transplant list in …

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Endoscopic therapy for Zenker diverticulum - the good and the bad
Authors: H. Feussner
Journal: Endoscopy (2007)

For decades, diverticulectomy and cervical myotomy using the open (cervical) approach was the treatment of choice for Zenker diverticulum. A minority of surgeons (in particular ENT specialists), however, had applied endoluminal treatment for many years; endoluminal dissection had been first introduced by Mosher in 1917. In the course of time, the tools changed, from scissors to CO2 lasers, argon beams, and so on, but the technique of internal dissection of the threshold between the diverticulum and the esophageal lumen never really became popular.
Difficult Choices for Two-Year Medical Schools
Authors: Glen R. Leymaster
Journal: JAMA (1972)

At the beginning of the 1972-1973 academic session, six two-year medical schools admitted students into their entering classes. For the newest, the University of Minnesota-Duluth, this class was its first. The University of North Dakota School of Medicine, on the other hand, dates its beginning to 1905. The others are components of Brown University, and of the universities of Hawaii, Nevada, and South Dakota. In 1972, Dartmouth and Rutgers, formerly two-year schools, were provisionally accredited as degreegranting institutions. Hawaii and Brown have announced plans and requested approval for granting degrees; action by the Liaison Committee on Medical Education is pending. The Duluth program is planned to become a degree-granting school almost immediately. Pressures are mounting for all two-year schools to convert. The responses of the educational institutions, the accrediting agencies, and the state legislatures that will be asked to fund the programs will surely influence the quality of medical education.
Boosting performance measure for measure
Authors: D. Stryer
Journal: BMJ (2003)

The American healthcare system contrasts with healthcare systems in all other countries. Far more money is spent on health care in the United States than in any other country. Also, the marketplace rather than regulatory mechanisms is entrusted with promoting innovation and addressing suboptimal performance and inefficiencies since insurance is provided through a mix of public and private sources. Despite the obvious differences between the American and other systems, the challenges of providing safe and effective care transcend borders and financing mechanisms. Ensuring that patients are able to obtain care, whether it be prevention, treatment, or palliation, is a priority for all developed nations, especially as patients are living longer and many are living with chronic illnesses such as coronary artery disease, diabetes, and asthma.

In an effort to narrow the gap between the best evidence based care possible and actual care, the American healthcare system has invested heavily in measurement and accountability. Over the past decade, numerous reports and data have become available to healthcare decision makers to facilitate quality improvement. In the private sector, the National Committee for Quality Assurance developed the health plan employer data and information set (HEDIS), a set of measures intended to assess the quality of …
Genetic and pharmacologic inactivation of cannabinoid CB1 receptor inhibits angiogenesis
Authors: Simona Pisanti, Paola Picardi, Lucia Prota, Maria Chiara Proto, Chiara Laezza, Paul G. McGuire, Lucia Morbidelli, Patrizia Gazzerro, Marina Ziche, Arup Das, Maurizio Bifulco
Journal: Blood (2011)
Higher Prevalence of Obsessive-Compulsive Symptoms in Patients With Blepharospasm Than in Patients With Hemifacial Spasm
Authors: Andreas Broocks, Andreas Thiel, Detlef Angerstein, Dirk Dressler
Journal: American Journal of Psychiatry (1998)

OBJECTIVE: The prevalences of obsessive-compulsive symptoms in patients suffering from blepharospasm and in those with hemifacial spasm were determined. The two conditions have similar symptoms, but only blepharospasm is etiologically linked to basal ganglia dysfunction. METHOD: After being interviewed with the Structured Clinical Interview for DSM-III-R, 13 patients with blepharospasm and 13 with hemifacial spasm completed the SCL-90-R and the Hamburg Obsession/Compulsion Inventory—Short Form. RESULTS: Patients in the blepharo~spasm group had significantly more obsessive-compulsive symptoms, as indicated by higher scores on the Hamburg Obsession/Compulsion Inventory—Short Form, than the patients with hemifacial spasm. SCL-90-R scores were in the normal range for nine and eight categories, respectively (out of nine). CONCLUSIONS: The findings provide additional support for the hypothesis that obsessive-compulsive symptoms are related to basal ganglia dysfunction.
The Hand: Surgical and Non-surgical Management
Authors: Reginald R. Cooper
Journal: JAMA (1978)

Although publications on hand surgery have perhaps exceeded the saturation point, the authors of this volume correctly identify a persistent need to make readily available the information necessary for diagnosis and management of all common clinical problems. This does indeed represent a rather ambitious venture. In nearly 500 profusely illustrated pages, a group of obviously qualified writers do exceptionally well at this task. The deliberate description of "a method rather than all methods of management" is commendable. In given instances, however, this might leave the reader feeling inadequately informed. After a brief introduction to the history of hand surgery, traditional chapters delineate anatomy and history and examination techniques. An imaginative section describes the facilities and equipment needed for treating patients with hand injuries. A thoughtful discussion on pitfalls wisely stresses the appropriate education of the patient for his vital role in the rehabilitation process. A timely admonition about limiting surgery
Epidemiology of Epidemic Dropsy
Authors: R. B. Lal, S. C. Roy
Journal: BMJ (1937)

THE BRITISH lower classes of society, were examined clinically and serologically to determine the incidence of syphilis.2. There were forty-three children, or 3.9 per cent., giving positive serological reactions.Among these were thirteen whose positive reactions were almost surely due to yaws, leaving thirty, or 2.7 per cent., with probable congenital syphilis.3. It is estimated that congenital syphilis is present in about 3 per cent. of all black and coloured children of Kingston.4. Syphilis doubtless reaches a much higher incidence among the entire population.The exact figure cannot be stated, but on the basis of evidence gathered elsewhere concerning the ratio of the incidence of syphilis in children to that for the entire population it may be said to be approximately 12 per cent.
Withdrawal of rifamide.
Authors: J D Williams
Journal: BMJ (1974)

Fibre and Irritable Bowels SIR,-I read with interest your leading article (1 June, p. 457) which referred to recent work on this disorder.I had just completed a survey of most of the medical journals of Africa south of the Sahara from 1960 to 1974 and had found no mention of this disease in Africans.In 1960 I had suggested as a tentative hypothesis that the rarity of non-infective colonic diseases in Africans was due to diets which contained large amounts of fibre-rich starchy carbo- hydrate.This may be called the "fibre hypothesis," those words being employed at that time.There appeared to be rarity of constipation, irritable bowel disease, diverti- cular disease, appendicitis, ulcerative colitis, haemorrhoids, polyps, and carcinoma of the large bowel and rectum.1The position does not seem to have changed much in the intervening 14 years.My clinical obsetrvations, based on some 30 years' medical ex- perience in East Africa, have been considerably amplified by my Uganda colleague, Mr. Denis Burkitt, and the studies of Mr. Neil Painter.There is a possibility that irritable bowel disease often precedes diverticular disease.It is therefore of interest that we are presenting shortly much new information, necropsy, radiological, and clinical, concern- ing the great rarity of diverticular disease in many countries in Africa and Asia.2At medical 'boards I had frequently retired
The Main Lines of the Short-Term Psychotherapy Project in Oslo
Authors: Astrid Heiberg
Journal: Psychotherapy and Psychosomatics (1978)

Case Reports| February 16 2010 The Main Lines of the Short-Term Psychotherapy Project in Oslo Subject Area: Psychiatry and Psychology Astrid Heiberg Astrid Heiberg Institute of Psychiatry, Oslo University, Oslo Search for other works by this author on: This Site PubMed Google Scholar Psychother Psychosom (1978) 29 (1-4): 309–311. https://doi.org/10.1159/000287148 Article history Published Online: February 16 2010 Content Tools Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Astrid Heiberg; The Main Lines of the Short-Term Psychotherapy Project in Oslo. Psychother Psychosom 31 December 1978; 29 (1-4): 309–311. https://doi.org/10.1159/000287148 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsPsychotherapy and Psychosomatics Search Advanced Search Article PDF first page preview Close Modal This content is only available via PDF. 1978Copyright / Drug Dosage / DisclaimerCopyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. You do not currently have access to this content.
Antibodies to HTLV-I in sera from patients with connective tissue diseases.
Authors: W Irvine, P White, G Cambridge
Journal: Annals of the Rheumatic Diseases (1989)

Antibodies to HTLV-I in sera from patients with connective tissue diseases SIR, It has been suggested that HTLV-I infection may be associated with the development of some connective tissue diseases (CTD), including poly-and dermatomyositis (PM and DM), systemic lupus erythematosus (SLE), scleroder- ma, and Sjogrens syndrome (SS).' 2 This was based on
Prevalence of Diabetes and Impaired Fasting Glucose in Korea
Authors: S.M. Kim, J.S. Lee, J. Lee, J.K. Na, J.H. Han, D.K. Yoon, S.H. Baik, D.S. Choi, K.M. Choi
Journal: Diabetes Care (2006)

The purpose of this study was to estimate the prevalence of diabetes and impaired fasting glucose (IFG) and their association with risk factors in the Korean population.The Korean National Health and Nutrition Survey 2001 was a nationally representative survey with a stratified multistage sampling design. Data from a comprehensive questionnaire, a physical examination, and blood tests were obtained from 5,844 Korean adults (2,513 men and 3,331 women) aged >20 years.The age-adjusted prevalence of diabetes in this Korean population was 7.6%, and the age-adjusted prevalences of previously diagnosed diabetes and newly diagnosed diabetes were 4.4 and 3.3%, respectively (fasting plasma glucose > or = 7.0 mmol/l). Overall, these results indicate that 8.1% or 1.4 million Korean men and 7.5% or 1.3 million Korean women have diabetes. The age-adjusted prevalence of IFG was 23.9%, using the new American Diabetes Association criteria (fasting plasma glucose 5.6-6.9 mmol/l). Diabetes prevalence increased with age and peaked in the oldest age-group; however, IFG prevalence did not show the same trend. Diabetes was found to be associated with age, BMI, blood pressure, triglyceride, HDL cholesterol, education levels, alcohol consumption, exercise, and a family history of diabetes.This study shows that diabetes and IFG are common in Korea, and about one-half of diabetes cases remain undiagnosed. These results emphasize the need to develop an urgent public program to improve the detection, prevention, and treatment of diabetes.