THE VALUE OF STEROIDS IN THE TREATMENT OF RHEUMATOID ARTHRITIS
Authors: PAUL W. CLOUGH
Journal: Annals of Internal Medicine (1955)

Editorial1 December 1955THE VALUE OF STEROIDS IN THE TREATMENT OF RHEUMATOID ARTHRITISPAUL W. CLOUGH, M.D.PAUL W. CLOUGH, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-43-6-1341 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe remarkable effects of corticotropin and cortisone in ameliorating the manifestations of rheumatoid arthritis, as first reported by Hench and his associates, undoubtedly marked a major advance in the treatment of this disease. Their observations have been amply confirmed. Adequate doses of cortisone, temporarily within the tolerance of the subject, will quickly relieve the pain and dissipate the evidences of acute inflammation in 95 per cent of the cases. The early enthusiasm was soon chilled, however, by the serious adverse effects caused by full doses of the drug and by the promptness and great regularity with which relapse followed an...1 Freyberg RH: Problems of prolonged cortisone treatment for rheumatoid arthritis, J. A. M. A. 147: 1538-1543, 1951. CrossrefMedlineGoogle Scholar2 Boland EW: Prolonged uninterrupted cortisone therapy in rheumatoid arthritis, Brit. M. J. 2: 191, 1951. CrossrefMedlineGoogle Scholar3 Price AE: Observations on use of cortisone and corticotropin in rheumatoid arthritis, J. Michigan M. Soc. 51: 1183, 1952. MedlineGoogle Scholar4 WardPolleySlocumbHench LEHFCHPS: Cortisone in treatment of rheumatoid arthritis, J. A. M. A. 152: 119-126, 1953. CrossrefMedlineGoogle Scholar5 WestNewns HFGR: Some effects of long-continued cortisone therapy in rheumatoid arthritis, Lancet 2: 515-517, 1952. CrossrefMedlineGoogle Scholar6 Copeman WS: Management of rheumatoid arthritis with prolonged cortisone administration, Brit. M. J. 1: 1109-1113, 1954. CrossrefMedlineGoogle Scholar7 BolletBunim AJJJ: The importance of serial joint x-rays in the evaluation of treatment of rheumatoid arthritis, M. Clin. North America 39: 439-445, 1955. CrossrefGoogle Scholar8 Holbrook WP: Cortisone, ACTH and phenylbutazone in long term therapy of rheumatoid arthritis, M. Clin. North America 39: 311-318, 1955. Google Scholar9 Bunim JJ: Evaluation of prolonged cortisone therapy in rheumatoid arthritis, Am. J. Med. 18: 27-40, 1955. CrossrefMedlineGoogle Scholar10 ShortBauer CLW: The course of rheumatoid arthritis in patients receiving simple medical and orthopedic measures, New England J. Med. 238: 142, 1948. CrossrefMedlineGoogle Scholar11 Ragan C: Rheumatoid arthritis, Bull. New York Acad. Med. 27: 63-74, 1951. MedlineGoogle Scholar12 TooneIrby ECR: Effect of cortisone in the long term treatment of rheumatoid arthritis, Am. J. Med. 18: 41-50, 1955. CrossrefMedlineGoogle Scholar13 Bunim JJ: Studies on metacortandralone and metacortandracin in rheumatoid arthritis, J. A. M. A. 157: 311-318, 1955. CrossrefMedlineGoogle Scholar14 Margolis HM: Effects of prednisone (Meticorten) on manifestations of rheumatoid arthritis, J. A. M. A. 158: 454-463, 1955. CrossrefMedlineGoogle Scholar15 Demartini F: Comparative effects of prednisone and cortisone, J. A. M. A. 158: 1505-1508, 1955. CrossrefMedlineGoogle Scholar16 Bollet AJ: Major undesirable side-effects resulting from prednisolone and prednisone, J. A. M. A. 158: 459-463, 1955. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: PAUL W. CLOUGH, M.D. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byRHEUMATISM AND ARTHRITIS: REVIEW OF AMERICAN AND ENGLISH LITERATURE OF RECENT YEARS (TWELFTH RHEUMATISM REVIEW)* Part IICHARLEY J. SMYTH, M.D., F.A.C.P., JOSEPH J. BUNIM, M.D., F.A.C.P., WILLIAM S. CLARK, M.D., F.A.C.P., DARRELL C. CRAIN, M.D., F.A.C.P., FELIX E. DEMARTINI, M.D., IVAN F. DUFF, M.D., F.A.C.P., EPHRAIM P. ENGLEMAN, M.D., F.A.C.P., DONALD C. GRAHAM, M.D., F.R.C.P. (C), MAX M. MONTGOMERY, M.D., F.A.C.P., BERNARD M. NORCROSS, M.D., F.A.C.P., HOWARD F. POLLEY, MARIAN W. ROPES, M.D., F.A.C.P., EDWARD F. ROSENBERG, M.D., F.A.C.P. 1 December 1955Volume 43, Issue 6Page: 1341-1346KeywordsAdrenocorticotropic hormoneDrugsInflammationRheumatoid arthritisSteroids ePublished: 1 December 2008 Issue Published: 1 December 1955 PDF downloadLoading ...