Obstructive Pulmonary Emphysema
Authors: JOHN B. HICKAM
Journal: Annals of Internal Medicine (1962)

Editorials1 July 1962Obstructive Pulmonary EmphysemaJOHN B. HICKAM, M.D., F.A.C.P.JOHN B. HICKAM, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-57-1-174 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptObstructive pulmonary emphysema is a common disorder which presents many problems to the practicing physician and the investigator. These problems include defining the disease by the pathologist, determining the cause, understanding and measuring the functional derangements, making the clinical diagnosis, and developing effective means of prevention and treatment of the primary disorder and its complications. Articles in the current issue of the ANNALS deal in detail with several of these subjects. A brief survey of some items of major interest in the field is presented here.There have been recent important contributions to the pathology of obstructive pulmonary emphysema. Classically,...References1. LEOPOLDGOUGH JGJ: The centrilobular form of hypertrophic emphysema and its relation to chronic bronchitis. Thorax 12: 219, 1957. CrossrefMedlineGoogle Scholar2. BOREN HG: Alveolar fenestrae. Relationship to the pathology and pathogenesis of pulmonary emphysema. Amer. Rev. Resp. Dis. 85: 328, 1962. MedlineGoogle Scholar3. DAYMAN H: Mechanics of airflow in health and in emphysema. J. Clin. Invest. 30: 1175, 1951. CrossrefMedlineGoogle Scholar4. GURTNERBRISCOECOURNAND HPWAA: Studies of the ventilation-perfusion relationships in the lungs of subjects with chronic pulmonary emphysema, following a single intravenous injection of radioactive krypton (Kr85). I. Presentation and validation of a theoretical model. J. Clin. Invest. 39: 1080, 1960. CrossrefMedlineGoogle Scholar5. RILEY RL: Effects of lung inflation on the pulmonary vascular bed, in Pulmonary Circulation, ed. by Adams, W. R., and Veith, I., Grune & Stratton, New York, 1959. Google Scholar6. HIMMELSTEINHARRISFRITTSCOURNAND APHWA: Effect of severe unilateral hypoxia on the partition of pulmonary blood flow in man. J. Thoracic Surg. 36: 369, 1958. CrossrefGoogle Scholar7. BERGOFSKYLEHRFULLERRIGATTOFISHMAN EHDEMAMAP: The effects of acute alkalosis and acidosis on the pulmonary circulation. Ann. N. Y. Acad. Sci. 92: 627, 1961. CrossrefGoogle Scholar8. FERRERHARVEYCATHCARTWEBSTERRICHARDSCOURNAND MIRMRICADWA: Some effects of digoxin upon the heart and circulation in man. Digoxin in cor pulmonale. Circulation 1: 161, 1950. CrossrefMedlineGoogle Scholar9. WESTDOLLERYHUGH-JONES JBCTP: The use of radioactive carbon dioxide to measure regional blood flow in the lungs of patients with pulmonary disease. J. Clin. Invest. 40: 1, 1961. CrossrefMedlineGoogle Scholar10. BALLSTEWARTNEWSHAMBATES WCPBLGDV: Regional pulmonary function studied with xenon133. J. Clin. Invest. 41: 519, 1962. CrossrefMedlineGoogle Scholar11. BARACHBICKERMAN RLHA: Pulmonary Emphysema, The Williams & Wilkins Company, Baltimore, 1956. Google Scholar12. ROCKEYTHOMPSONBLAZSIK EESACF: The evaluation and early results of tracheal fenestration. Amer. Rev. Resp. Dis. 79: 773, 1959. Google Scholar13. TABAKINADHIKANMILLER BSPKDB: Objective long-term evaluation of the surgical treatment of diffuse obstructive emphysema. Amer. Rev. Resp. Dis. 80: 825, 1959. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Department of Medicine Indiana University Medical Center 1100 West Michigan Street Indianapolis 7, Indiana PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByPulmonary Muscular HyperplasiaA CLINICO-PATHOLOGIC STUDY OF EMPHYSEMA-THE IMPORTANCE OF EARLY DIAGNOSIS 1 July 1962Volume 57, Issue 1Page: 174-177KeywordsEmphysemaPathologists Issue Published: 1 July 1962 PDF DownloadLoading ...