The Nephrotic Syndrome Secondary to Acute Glomerulonephritis During Falciparum Malaria
Authors: MARVIN BERGER
Journal: Annals of Internal Medicine (1967)

Article1 December 1967The Nephrotic Syndrome Secondary to Acute Glomerulonephritis During Falciparum MalariaMARVIN BERGER, LEONARD M. BIRCH, NICHOLAS F. CONTEMARVIN BERGER, LEONARD M. BIRCH, NICHOLAS F. CONTEAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-67-6-1163 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlthough endemic malaria has been virtually eradicated from this country, our present military commitment in Southeast Asia, together with the ease of worldwide travel into endemic areas, makes it incumbent upon physicians to be cognizant of the various manifestations of this disorder. Renal tubular disease in falciparum malaria as manifested by hemoglobinuric nephrosis ("blackwater fever") is a well-established entity; the occurrence of significant glomerular dysfunction is not well-recognized.Attention was drawn to this possibility by Thayer (1) in 1898 who discussed 340 patients, 58% of whom had albuminuria and 25%, cylindruria during the course of subtertian malaria. Since then sporadic...References1. THAYER WS: Nephritis of malarial origin. Trans. Ass. Amer. Physicians 13: 339, 1898. Google Scholar2. HOLMES A COURT AW: Sub-tertian malaria—a report of thirty-five cases. Med. J. Aust. 1: 63, 1918. CrossrefGoogle Scholar3. GOLDIE H: Notes on the association of malaria with nephritis. Trans. Roy. Soc. Trop. Med. Hyg. 25: 503, 1930. CrossrefGoogle Scholar4. GIGLIOLI G: Malaria and renal disease, with special reference to British Guiana. I. Introduction. Ann. Trop. Med. Parasit. 56: 101, 1962. CrossrefMedlineGoogle Scholar5. MCCABE ME: Malaria—a military medical problem yet with us. Med. Serv. J. Canada 22: 313, 1966. MedlineGoogle Scholar6. ALLEN GP: Some post-mortem observations on twenty-six cases of subtertian malaria. Trans. Roy. Soc. Trop. Med. Hyg. 20: 196, 1926. CrossrefGoogle Scholar7. SPITZ S: The pathology of acute falciparum malaria. Milit. Surgeon 99: 555, 1945. Google Scholar8. SCHREINER GE: The nephrotic syndrome, in Diseases of the Kidney, edited by STRAUSS, M. B., WELT, L. G. Little, Brown and Co., Boston, 1963, chap. 12. Google Scholar9. BLOUNT RE: Observations regarding malaria in Viet Nam. Surgeon General's Office Letter, Jan. 29, 1966. Google Scholar10. LAHA PN: Malarial nephritis with an illustrative case report. J. Indian Med. Ass. 15: 46, 1945. MedlineGoogle Scholar11. DUBB A: Nephrotic syndrome associated with malaria. Proc. Mine Med. Officers Ass. 44: 76, 1964. MedlineGoogle Scholar12. MANSON-BAHR PH: Manson's Tropical Diseases, 16th ed. The Williams & Wilkins Co., Baltimore, 1966, p. 45. Google Scholar13. MAEGRAITH B: Pathologic Processes in Malaria and Blackwater Fever. Blackwell Scientific Publications, Oxford, 1948, chap. 7. Google Scholar14. EWING J: A Case of malarial nephritis, with massing of parasites in the kidney. Trans. Ass. Amer. Physicians 16: 450, 1901. Google Scholar15. MANSON-BAHR PH: Manson's Tropical Diseases, 16th ed. The Williams & Wilkins Co., Baltimore, 1966, p. 52-54. Google Scholar16. WARDCONRAN PAPB: Immunopathologic studies of simian malaria. Milit. Med. 131 (suppl.): 1225, 1966. CrossrefGoogle Scholar17. DIXON FJ: Comments on immunopathology. Ibid., p. 1233. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: MARVIN BERGER; LEONARD M. BIRCH; NICHOLAS F. CONTEAffiliations: MC USA Phoenixville, PennsylvaniaFrom the Department of Medicine, Valley Forge General Hospital, Phoenixville, Pa.Requests for reprints should be addressed to Marvin Berger, M.D., 12 E. 86th St., New York, N. Y. 10028. 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W. KIBUKAMUSOKE, M.D.Renal involvement in malariaIMMUNE COMPLEXES IN THE NEPHROTIC SYNDROME OF AFRICAN CHILDRENEVIDENCE FOR SOLUBLE IMMUNE COMPLEXES IN THE PATHOGENESIS OF THE GLOMERULONEPHRITIS OF QUARTAN MALARIA 1 December 1967Volume 67, Issue 6Page: 1163-1171KeywordsArmed forcesBiopsyFeversGlomerulonephritisHemoglobinHospital medicineMalariaMilitary medicineRenal diseases ePublished: 1 December 2008 Issue Published: 1 December 1967 PDF downloadLoading ...