Mycobacterial and Mycotic Antibodies in Sera of Patients with Sarcoidosis
Authors: JOHN S. CHAPMAN
Journal: Annals of Internal Medicine (1961)

Article1 December 1961Mycobacterial and Mycotic Antibodies in Sera of Patients with SarcoidosisResults of Studies Using Agar Double-diffusion TechniqueJOHN S. CHAPMAN, M.D., F.A.C.P.JOHN S. CHAPMAN, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-55-6-918 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn the official pronouncement of the Committee on Sarcoidosis of the National Research Council, sarcoidosis is a "disease of unknown etiology." This view is not universally accepted. Since Pinner's description of sarcoidosis as an anergic form of tuberculosis (1), a view most notably seconded by Scadding (2), discussion has involved not only the tuberculous etiology, but also the possibility that ultimately the condition known as sarcoidosis may result from identical reactions to many different agents. The multitudinous possibilities have been ably expounded by Refvem (3).In general, American authors have agreed with the opinion of Lofgren (4) that sarcoidosis is...References1. PINNER M: On the etiology of sarcoidosis. Amer. Rev. Tuberc. 54: 582, 1946. Google Scholar2. SCADDINC JG: Mycobacterium tuberculosis in the aetiology of sarcoidosis. Brit. Med. J. 2: 1617, 1960. CrossrefMedlineGoogle Scholar3. REFVEM O: The pathogenesis of sarcoidosis (Boeck). Acta Med. Scand. 149: 11, 1954. Google Scholar4. LOFGREN S: Immunological and aetiological aspects of sarcoidosis. Acta Tuberc. Scand. (Supp.) 45: 19, 1959. Google Scholar5. CUMMINGSDUNNERSCHMIDTBARNWELL MMERHJB: Concepts of epidemiology of sarcoidosis. Postgrad. Med. J. 19: 437, 1956. CrossrefGoogle Scholar6. SILTZBACHEHRLICH LEJC: The Kveim-Nickerson reaction in sarcoidosis. Amer. J. Med. 22: 841, 1957. CrossrefMedlineGoogle Scholar7. 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Transactions of the Sixteenth Conference on Chemotherapy of Tuberculosis, Washington, Veterans Administration, Department of Medicine & Surgery, 1957. Google Scholar13. PARLETTYOUMANS ECCE: Antigenic relationships between ninety-eight strains of mycobacteria using gel diffusion precipitation techniques. Amer. Rev. Tuberc. 77: 450, 1958. Google Scholar14. CHAPMAN JS: A serological reaction associated with sarcoidosis. Proc. Soc. Exp. Biol. Med. 107: 321, 1961. CrossrefMedlineGoogle Scholar15. CROWLE AJ: A simplified micro double diffusion agar precipitin technique. J. Lab. Clin. Med. 52: 784, 1958. MedlineGoogle Scholar16. OUDIN J: L'analyse immunochimique qualitative; methode par diffusion des antigens au sein d'immunoserum precipitant gelose. Ann. Inst. Pasteur 75: 30, 1948. Google Scholar17. OUCHTERLONY O: Antigen-antibody reactions in gels. IV. Types of reaction in coordinated systems of diffusion. Acta Path. Microbiol. Scand. 32: 231, 1953. CrossrefGoogle Scholar18. DEWLETTLEFKOWITZFULAYFILCHRISTIANSONCHAPMAN HJLRLJS: A study of reactions to various anonymous mycobacterial antigens. To be published. Google Scholar19. . Unpublished data. Google Scholar20. SALVIN SB: Quantitative studies on the serological relationships of fungi. J. Immun. 65: 617, 1950. MedlineGoogle Scholar21. HEINER DC: Diagnosis of histoplasmosis using precipitin reactions in agar gel. Pediatrics 22: 616, 1958. MedlineGoogle Scholar22. BERNARDOWENS LAJC: Isolated cryptococcosis associated with Boeck's sarcoid. Arch. Intern. Med. 106: 101, 1960. CrossrefMedlineGoogle Scholar23. CUNLIFFE AC: Discussion at First International Conference on Sarcoidosis, London, 1958. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Dallas, TexasFrom the Department of Internal Medicine and the William Buchanan Laboratory of Tne University of Texas Southwestern Medical School.This study was supported by a grant from the Dallas Tuberculosis Association.Requests for reprints should be addressed to John S. Chapman, M.D., Division of Postgraduate Education, The University of Texas Southwestern Medical School, 5323 Harry Hines Boulevard, Dallas 35, Texas. 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SIEKER, M.D., F.A.C.P.Zur Immunologie der SarkoidoseErste wissenschaftliche SitzungMacrocryoglobulinemia and sarcoidosisSarcoidosisAtypical mycobacteria as a probable cause of chronic bone diseaseSarcoidosis among children in Utah and IdahoFurther Studies of Mycobacterial Antibodies in the Sera of Sarcoidosis Patients1Cutaneous Reactions of Household Contacts of Sarcoidosis PatientsImmunological Diagnosis of the Upper Urinary Tract Infections (Pyelonephritis): Agar Gel Diffusion TechniqueThe present status of the unclassified mycobacteriaHigh School Student Attitudes on Tuberculin Testing 1 December 1961Volume 55, Issue 6Page: 918-924KeywordsAntibodiesAntigensBlastomycesCoccidioidesEtiologyResearch laboratoriesSarcoidosisTechnicians Issue Published: 1 December 1961 PDF downloadLoading ...