Peculiar Acral Erythema Secondary to High-Dose Chemotherapy for Acute Myelogenous Leukemia
Authors: WALTER H. C. BURGDORF
Journal: Annals of Internal Medicine (1982)

Brief Reports1 July 1982Peculiar Acral Erythema Secondary to High-Dose Chemotherapy for Acute Myelogenous LeukemiaWALTER H. C. BURGDORF, M.D., WILLIAM A. GILMORE, M.D., RALPH G. GANICK, M.D.WALTER H. C. BURGDORF, M.D., WILLIAM A. GILMORE, M.D., RALPH G. GANICK, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-97-1-61 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptCutaneous changes limited to the hands have been described in patients receiving cancer chemotherapy with regimens involving bleomycin. We describe a patient with a peculiar acral erythema treated with high-dose chemotherapy not incorporating bleomycin.A 50-year-old woman developed dysarthria, expressive aphasia, and fever while on vacation in New England. When examined in the local hospital emergency room, she had a leukocyte count of 18 000/mm3 with numerous immature and blast myelocytes. Bone marrow examination confirmed the diagnosis of acute myelogenous leukemia. Computed tomography showed a left posterior temporal lobe density consistent with a leukemic infiltrate or hemorrhage.The patient was...References1. VAUGHAN W, KARP J, and BURKE P. Long chemotherapy-free remissions after single-cycle timed-sequential chemotherapy for acute myelocytic leukemia. Cancer. 1980;45:859-65. CrossrefMedlineGoogle Scholar2. TEUTSCH C, LIPTON A, and HARVEY H. Raynaud's phenomenon as a side effect of chemotherapy with vinblastine and bleomycin for testicular carcinoma. Cancer Treat Rep. 1977;61:925-6. MedlineGoogle Scholar3. ROTHBERG H. Raynaud's phenomenon after vinblastine-bleomycin chemotherapy. Cancer Treat Rep. 1978;62:569-70. MedlineGoogle Scholar4. SOBLE A. Chronic bleomycin-associated Raynaud's phenomenon [Letter]. Cancer Treat Rep. 1978;62:570. MedlineGoogle Scholar5. CHERNICOFF D, BUKOWSKI R, and YOUNG J. Raynaud's phenomenon after bleomycin treatment [Letter]. 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C. BURGDORF, M.D.; WILLIAM A. GILMORE, M.D.; RALPH G. GANICK, M.D.Affiliations: Department of Dermatology University of Oklahoma Health Sciences Center Oklahoma City Clinic Oklahoma City, Oklahoma PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDesign of amino acid- and carbohydrate-based anticancer drugs to inhibit polymerase ηCutaneous Adverse Drug ReactionsRecognition and Management of Toxic Erythema of Chemotherapy for the Inpatient DermatologistCytarabine ears – A side effect of cytarabine therapyCommon Cutaneous Side Effects of Anti-cancer AgentsAdverse Cutaneous Reactions to Chemotherapeutic AgentsCutaneous Adverse Drug ReactionsThe interface reaction pattern in the skin: an integrated review of clinical and pathological featuresKutane ArzneimittelreaktionenKutane ArzneimittelreaktionenSemelles orthopédiques et prévention du syndrome mains-pieds lié aux traitements anticancéreuxMultikinase Inhibitor-Induced Hand–Foot Skin Reaction: A Review of Clinical Presentation, Pathogenesis, and Management"Red Hand Syndrome" Due to Cytarabine in a Case of Mantle Cell LymphomaAutologous GVHD?Risk Factors for Cytarabine-Induced Cutaneous Toxicity in Patients with Haematological MalignanciesAntimetabolite ReactionsThe History of Supportive OncodermatologyConnect the dotsTECToxic erythema of chemotherapy following i.v. 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LOKICH, M.D., CHERYL MOORE, R.N.Acral Erythema and HydroxyureaFRANCES SANDLER SILVER, M.D., LUIS R. ESPINOZA, M.D., ROBERT C. HARTMANN, M.D.Cancer Chemotherapy and Acral ErythemaHENRY SCHNEIDERMAN, M.D., NICHOLAS ROBERT, M.D.Cancer Chemotherapy and Acral ErythemaCATHERINE CORDONNIER, M.D., JEAN CLAUDE ROUJEAU, M.D., JEAN PAUL VERNANT, M.D., SOPHIE MATHERON, M.D., GERARD GANEM, M.D.Arzneireaktionen 1 July 1982Volume 97, Issue 1Page: 61-62KeywordsAcute myeloid leukemiaBone marrowCancer chemotherapyComputed axial tomographyEmergency departmentErythemaFeversHemorrhageHigh-dose chemotherapyTemporal lobe ePublished: 1 December 2008 Issue Published: 1 July 1982 PDF downloadLoading ...