Cutaneous Lichen Amyloidosis and Familial Medullary Thyroid Carcinoma
Authors: Jorge P. Ferrer, Irene Halperin, Josep Palou
Journal: Annals of Internal Medicine (1990)

Letters and Corrections1 April 1990Cutaneous Lichen Amyloidosis and Familial Medullary Thyroid CarcinomaJorge P. Ferrer, MD, Irene Halperin, MD, Josep Palou, MDJorge P. Ferrer, MDSearch for more papers by this author, Irene Halperin, MDSearch for more papers by this author, Josep Palou, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-112-7-551 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editor: Gagel and colleagues (1) recently described an association of hereditary cutaneous amyloidosis with multiple endocrine neoplasia type 2a. We recently encountered an identical skin lesion in a case of hereditary medullary thyroid carcinoma that we believe confirms the hypothesis that the simultaneous appearance of these rare diseases is not a mere coincidence.A 30-year-old woman was evaluated at our clinic in the setting of a familial-medullary-thyroid-carcinoma screening program. She was asymptomatic except for slight interscapular pruritus of several years duration. Physical examination revealed a right thyroid nodule, 0.8 cm in diameter, and a 2-by-3-cm papular and pigmented...References1. GagelLevyDonald RMT. Multiple endocrine neoplasia type 2a associated with cutaneous lichen amyloidosis. Ann Intern Med. 1989;111:802-6. LinkGoogle Scholar2. FarndonLeightDilley JGW. Familial medullary thyroid carcinoma without associated endocrinopathies: a distinct clinical entity. Br J Surg. 1986;73:278-81. CrossrefMedlineGoogle Scholar3. JacksonVan DykeTalpos CDG. MEN-2 associations suggest a linear order of specific endocrine tumor genes. Horm Metab Res Suppl. 1989;21:9-13. MedlineGoogle Scholar4. SobolNarodNakamura HSY. Screening for multiple endocrine neoplasia type 2a with DNA-polymorphism analysis. N Engl J Med. 1989;321:996-1001. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByCutaneous Amyloidosis: A Concept ReviewMultiple cutaneous neuromas and macular amyloidosis associated with medullary thyroid carcinomaProphylactic Thyroidectomy in Multiple Endocrine Neoplasia Type 2ADiagnosis and management of medullary thyroid carcinomaWhen “The 7-Year Itch” is Indicative of an Endocrine Malignant ConditionMultiple Endocrine Neoplasia Type 2Notalgia paresthetica: clinical, physiopathological and therapeutic aspects. A study of 12 casesGenetic Heterogeneity of Familial Primary Cutaneous Amyloidosis: Lack of Evidence for Linkage with the Chromosome 10 Pericentromeric Region in Chinese FamiliesMedullary Thyroid Carcinoma: Recent Advances and Management UpdateMultiple Endocrine Neoplasia 2 (Men 2)/Men 2A (Sipple Syndrome)A kindred with multiple endocrine neoplasia type 2A associated with pruritic skin lesionsSipple syndrome with lichen amyloidosis as a paracrinopathySipple syndrome with lichen amyloidosis as a paracrinopathy: Pleiotropy, heterogeneity, or a contiguous gene?Primary localized cutaneous amyloidosis and familial medullary thyroid carcinomaMedullary Thyroid Cancer: Diagnosis and Management 1 April 1990Volume 112, Issue 7Page: 551-552KeywordsAmyloidosisGenetic diseasesLesionsMedullary thyroid carcinomaMultiple endocrine neoplasiaPruritusThyroid Issue Published: 1 April 1990 PDF DownloadLoading ...