Silo-Filler's Disease, the Acute Respiratory Distress Syndrome, and Oxides of Nitrogen
Authors: James F. Leavey, Robert L. Dubin, Navdeep Singh, David A. Kaminsky
Journal: Annals of Internal Medicine (2004)

Letters7 September 2004Silo-Filler's Disease, the Acute Respiratory Distress Syndrome, and Oxides of NitrogenJames F. Leavey, MD, Robert L. Dubin, MD, Navdeep Singh, MD, and David A. Kaminsky, MDJames F. Leavey, MDFrom The University of Vermont College of Medicine, Fletcher Allen Health Care, Burlington, VT 05405.Search for more papers by this author, Robert L. Dubin, MDFrom The University of Vermont College of Medicine, Fletcher Allen Health Care, Burlington, VT 05405.Search for more papers by this author, Navdeep Singh, MDFrom The University of Vermont College of Medicine, Fletcher Allen Health Care, Burlington, VT 05405.Search for more papers by this author, and David A. Kaminsky, MDFrom The University of Vermont College of Medicine, Fletcher Allen Health Care, Burlington, VT 05405.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-141-5-200409070-00031 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Editor's Note:The second author of the following Clinical Observation was one of a dozen Associates of the American College of Physicians selected to present a clinical vignette at the 2003 Annual Session in Philadelphia. We are proud to present this case report through a special arrangement with the Council of Associates of the College.TO THE EDITOR:Background: Oxides of nitrogen can both harm and help human health. For example, silo-filler disease is a form of acute lung injury caused by exposure to nitrogen dioxide (NO2), but inhaled nitric oxide can improve oxygenation in patients with the acute respiratory distress ...References1. Douglas WW, Hepper NG, Colby TV. Silo-filler's disease. Mayo Clin Proc. 1989;64:291-304. [PMID: 2704252] CrossrefMedlineGoogle Scholar2. Hart CM. Nitric oxide in adult lung disease. Chest. 1999;115:1407-17. [PMID: 10334161] CrossrefMedlineGoogle Scholar3. Hayhurst ER, Scott E. Four cases of sudden death in a silo. JAMA. 1914;63:15702. Google Scholar4. Grayson RR. Silage gas poisoning: nitrogen dioxide pneumonia, a new disease in agricultural workers. Ann Intern Med. 1956;45:393-408. [PMID: 13363168] LinkGoogle Scholar5. Sokol J, Jacobs SE, Bohn D. Inhaled nitric oxide for acute hypoxemic respiratory failure in children and adults. Cochrane Database Syst Rev. 2003:CD002787. [PMID: 12535438] MedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From The University of Vermont College of Medicine, Fletcher Allen Health Care, Burlington, VT 05405. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByPulmonary Edema Occurring after Nitric Acid ExposureToxic Gases and VaporsAcute Responses to Toxic ExposuresToxic gasesInhaled nitric oxide for the adjunctive therapy of severe malaria: Protocol for a randomized controlled trialAcute Pulmonary Responses to Toxic Exposures 7 September 2004Volume 141, Issue 5Page: 410-411KeywordsAcute respiratory distress syndromeHemodynamicsInhalationLungsNitric oxideOxygenPulmonary arteriesPulmonary diseasesToxicityVentilators ePublished: 7 September 2004 Issue Published: 7 September 2004 CopyrightCopyright © 2004 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...