Acute Hepatitis A in Patients with Chronic Hepatitis C
Authors: Beat Helbling, Eberhard L. Renner, Raoul Kammerlander
Journal: Annals of Internal Medicine (1999)

Letters17 August 1999Acute Hepatitis A in Patients with Chronic Hepatitis CBeat Helbling, MD, Eberhard L. Renner, MD, and Raoul Kammerlander, MDBeat Helbling, MDUniversity Hospital; CH-8091 Zurich, Switzerland (Helbling)University Hospital; CH-8091 Zurich, Switzerland (Renner)Swiss Federal Office of Public Health; CH-3003 Berne, Switzerland (Kammerlander), Eberhard L. Renner, MDUniversity Hospital; CH-8091 Zurich, Switzerland (Helbling)University Hospital; CH-8091 Zurich, Switzerland (Renner)Swiss Federal Office of Public Health; CH-3003 Berne, Switzerland (Kammerlander), and Raoul Kammerlander, MDUniversity Hospital; CH-8091 Zurich, Switzerland (Helbling)University Hospital; CH-8091 Zurich, Switzerland (Renner)Swiss Federal Office of Public Health; CH-3003 Berne, Switzerland (Kammerlander)Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-131-4-199908170-00025 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Acute hepatitis A has been reported to carry a 35% case-fatality rate in patients with preexisting chronic hepatitis C (1). This contrasts with clinical experience, in which acute hepatitis A rarely takes a serious course. Nevertheless, the general vaccination of all patients with chronic hepatitis C against hepatitis A virus has been strongly advocated (2, 3). We used surveillance data prospectively collected by the Swiss Federal Office of Public Health to reassess the case-fatality rate of acute hepatitis A in patients with chronic hepatitis C. Reporting of markers for viral hepatitis to the Swiss Federal Office of ...References1. Vento S, Garofano T, Renzini C, Cainelli F, Casali F, Ghironzi T, et al . Fulminant hepatitis associated with hepatitis A virus superinfection in patients with chronic hepatitis C. N Engl J Med. 1998;338:286-90. CrossrefMedlineGoogle Scholar2. Pressemitteilung. Neue Information aus dem The New England Journal of Medicine: Hepatitis A und C: Eine tödliche Kombination! Schweizerische Aerztezeitung. 1998;79:350. Google Scholar3. Berenguer M, Wright TL. Are HCV-infected individuals candidates for hepatitis A vaccine? Lancet. 1998;1:924-5. CrossrefGoogle Scholar4. Kammerlander R. Hepatitis B in Switzerland: analysis of surveillance data of acute hepatitis B 1984-1993 [Thesis]. London: London School of Hygiene and Tropical Medicine; 1994. Google Scholar Author, Article, and Disclosure InformationAffiliations: University Hospital; CH-8091 Zurich, Switzerland (Helbling)University Hospital; CH-8091 Zurich, Switzerland (Renner)Swiss Federal Office of Public Health; CH-3003 Berne, Switzerland (Kammerlander) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByImmunization Coverage of Inmates in Spanish PrisonsAcute Viral HepatitisHepatitis A virus vaccination in persons with hepatitis C virus infection: Consequences of quality measure implementationHepatitis CEASL Clinical Practice Guidelines: Management of hepatitis C virus infectionAnti-hepatitis A virus seroprevalence among patients with chronic viral liver disease in KoreaHepatitis A virus infection suppresses hepatitis C virus replication and may lead to clearance of HCVVaccination against hepatitis a in patients with chronic liver diseaseHepatitis viruses and human immunodeficiency virus co-infection: pathogenisis and treatmentCost effectiveness of hepatitis A/B versus hepatitis B vaccination for US prison inmatesHepatitis A virus infection in hepatitis C Brazilian patientsHAV infection in chronic liver disease: a rationale for vaccinationVacunación contra la hepatitis A y la hepatitis B en pacientes portadores del virus de la hepatitis CAnti-hepatitis a virus seroprevalence and seroconversion in a cohort of patients with chronic viral hepatitisThe cost-effectiveness of vaccinating chronic hepatitis C patients against hepatitis A1Hepatitis A: Old and New 17 August 1999Volume 131, Issue 4Page: 314KeywordsChronic hepatitis CChronic liver diseaseClinical epidemiologyHepatitis AHepatitis A virusHepatitis C virusLiver diseasesPatient advocacyPrevention, policy, and public healthQuestionnaires Issue Published: 17 August 1999 CopyrightCopyright © 1999 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...