Chemotherapy and Chemoprophylaxis of Travelers' Diarrhea
Authors: Herbert L. Dupont, Charles D. Ericsson, Philip C. Johnson
Journal: Annals of Internal Medicine (1985)

Editorials1 February 1985Chemotherapy and Chemoprophylaxis of Travelers' DiarrheaHERBERT L. DUPONT, M.D., CHARLES D. ERICSSON, M.D., PHILIP C. JOHNSON, M.D.HERBERT L. DUPONT, M.D.Search for more papers by this author, CHARLES D. ERICSSON, M.D.Search for more papers by this author, PHILIP C. JOHNSON, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-102-2-260 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptDiarrhea continues to occur among persons traveling from low risk parts of the world to developing areas where enteric infection is hyperendemic in the local population. The causes of travelers' diarrhea are varied; however, at least 80% of cases are produced by bacterial agents, which explains the remarkable efficacy of antimicrobial agents in the treatment and prevention of the illness. Although not entirely effective, exercising care in where and what one eats and drinks is the most practical means of reducing the likelihood of developing diarrhea while in areas of high risk. Some travelers might use chemoprophylactic measures while traveling....References1. KEANWATERS BS. The diarrhea of travelers. III. Drug prophylaxis in Mexico. N Engl J Med. 1959;261:71-4. CrossrefMedlineGoogle Scholar2. SACK R. Antimicrobial prophylaxis of travellers' diarrhea: a summary of studies using doxycycline or trimethoprim and sulphamethoxazole. Scand J Gastroenterol [suppl]. 1983;84:111-7. Google Scholar3. MURRAYRENSIMERDUPONT BEH. Emergence of high-level trimethoprim resistance in fecal Escherichia coli during oral administration of trimethoprim or trimethoprim-sulfamethoxazole. N Engl J Med. 1982;306:130-5. CrossrefMedlineGoogle Scholar4. CARLSONTHORNTONDUPONTWESTMATHEWSON JSHAJ. Comparative in vitro activities of ten antimicrobial agents against bacterial enteropathogens. 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DUPONTSULLIVANPICKERINGHAYNESACKERMAN HPLGP. Symptomatic treatment of diarrhea with bismuth subsalicylate among students attending a Mexican university. Gastroenterology. 1977;73(4 pt 1):715-8. CrossrefMedlineGoogle Scholar10. DUPONTREVESGALINDOSULLIVANWOODMENDIOLA HREPLJ. Treatment of travelers' diarrhea with trimethoprim/sulfamethoxazole and with trimethoprim alone. N Engl J Med. 1982;307:841-4. CrossrefMedlineGoogle Scholar11. DUPONTERICSSONGALINDO HCE. Furazolidone versus ampicillin in the treatment of travelers' diarrhea. Antimicrob Agents Chemother. 1984;26:160-3. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: The University of Texas Health Science Center at Houston Houston, Texas PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByDiarrhea at the SummitProphylactic Antimicrobials for Traveler's Diarrhea: An Early HistorySingle-dose antibiotic treatment for travellers' diarrhoeaPrevention and Treatment of Traveler's DiarrheaCyst acquisition rate for Giardia lamblia in backcountry travelers to Desolation Wilderness, Lake TahoeProphylaxe der ReisediarrhöEpidemiology of wilderness-acquired diarrhea: implications for prevention and treatmentGastrointestinal InfectionPrevention of Traveler’s Diarrhea: A Double-Blind Randomized Trial with Saccharomyces cerevisiae Hansen CBS 5926Update on traveler's diarrheaNorfloxacin: A New Targeted Fluoroquinolone Antimicrobial AgentJOHN S. WOLFSON, M.D., DAVID C. HOOPER, M.D.Infectious Disease Problems for the TravelerTrimethoprim-Sulfamethoxazole and Other SulfonamidesCiprofloxacin or Trimethoprim-Sulfamethoxazole as Initial Therapy for Travelers' Diarrhea A Placebo-Controlled, Randomized TrialCHARLES D. ERICSSON, M.D., PHILIP C. JOHNSON, M.D., HERBERT L. DUPONT, M.D., DONNA R. MORGAN, Ph.D., JO ANN M. BITSURA, M.P.H., F. JAVIER DE LA CABADA, M.D.Prevention of traveler's diarrhea by the tablet form of bismuth subsalicylateGeneral internal medicine 1 February 1985Volume 102, Issue 2Page: 260-261KeywordsAntimicrobialsChemopreventionChemotherapyDiarrhea Issue Published: 1 February 1985 PDF DownloadLoading ...