Taking the Idiopathic Out of Intestinal Pseudo-obstruction
Authors: WILLIAM J. SNAPE
Journal: Annals of Internal Medicine (1981)

Editorials1 November 1981Taking the Idiopathic Out of Intestinal Pseudo-obstructionWILLIAM J. SNAPE JR., M.D.WILLIAM J. SNAPE JR., M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-95-5-646 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe term intestinal pseudo-obstruction describes a group of syndromes found in patients with symptoms that mimic those of organic intestinal obstruction, although no obstructing lesion can be found (1). Abnormalities in the intestinal smooth muscle or in the autonomic nervous system modulation of smooth muscular contraction, which can cause defective intestinal propulsion, apparently cause the symptom complex. But often its cause remains unknown, and as a result the symptom complex has been identified by various names (1). Recent technologic improvements, however, have allowed increased recognition of patients with this syndrome, and improved methods for the study of neuromuscular dysfunction will...References1. SCHUFFLERROHRMANNCHAFFEEBRANDDELANEYYOUNG MCRDJJ. Chronic intestinal pseudo-obstruction. A report of 27 cases and review of the literature. Medicine. 1981;60:173-96. CrossrefMedlineGoogle Scholar2. FAULKANURASFREEMAN DSJ. Idiopathic chronic intestinal pseudo-obstruction: use of central venous nutrition. JAMA. 1978;240:2075-6. CrossrefMedlineGoogle Scholar3. SNAPECARLSONMATARAZZOCOHEN WGSS. Evidence that abnormal myoelectrical activity produces colonic motor dysfunction in the irritable bowel syndrome. Gastroenterology. 1977;72:383-7. CrossrefMedlineGoogle Scholar4. BATTLESNAPEALAVICOHENBRAUNSTEIN WWASS. Colonic dysfunction in diabetes mellitus. Gastroenterology. 1980;79:1217-21. CrossrefMedlineGoogle Scholar5. BATTLESNAPEWRIGHT WWS. Abnormal colonic motility in progressive systemic sclerosis. Ann Intern Med. 1981;94:749-52. LinkGoogle Scholar6. CHRISTENSEN J. The controls of gastrointestinal movements: some old and some new views. N Engl J Med. 1971;285:85-98. CrossrefMedlineGoogle Scholar7. SCHUFFLERPOPE MC. Esophageal motor dysfunction in idiopathic intestinal pseudoobstruction. Gastroenterology. 1976;70:677-82. CrossrefMedlineGoogle Scholar8. LEWISDANIELSARNAWATERFALLMARZIO TESWL. Idiopathic intestinal pseudoobstruction: report of a case, with intraluminal studies of mechanical and electrical activity, and a response to drugs. Gastroenterology. 1978;74:107-11. CrossrefMedlineGoogle Scholar9. SULLIVANSNAPEMATARAZZOPETROKUBIJEFFRIESCOHEN MWSRGS. Gastrointestinal myoelectrical activity in idiopathic intestinal pseudo-obstruction. N Engl J Med. 1977;297:233-8. CrossrefMedlineGoogle Scholar10. SNAPEWRIGHTCOHENBATTLE WSSW. The gastrocolic response: evidence for a neural mechanism. Gastroenterology. 1979;77:1235-40. CrossrefMedlineGoogle Scholar11. BURKS T. Actions of drugs on gastrointestinal motility. In: JOHNSON LR, ed. Physiology of the Gastrointestinal Tract. New York: Raven Press; 1981:495-516. Google Scholar12. SCHUFFLERLOWEBILL MMA. Studies of idiopathic intestinal pseudoobstruction: I. Hereditary hollow visceral myopathy: clinical and pathological studies. Gastroenterology. 1977;73:327-38. CrossrefMedlineGoogle Scholar13. SCHUFFLERPOPE MC. Studies of idiopathic intestinal pseudoobstruction: II. Hereditary hollow visceral myopathy: family studies. Gastroenterology. 1977;73:339-44. CrossrefMedlineGoogle Scholar14. SCHUFFLERBIRDSUMICOOK MTSA. A familial neuronal disease presenting as intestinal pseudoobstruction. Gastroenterology. 1978;75:889-98. CrossrefMedlineGoogle Scholar15. BANNISTERHOYES RA. Generalised smooth-muscle disease with defective muscarinic-receptor function. Br Med J. 1981;282:1015-8. CrossrefMedlineGoogle Scholar16. SCHUFFLERREITCH ME. Chronic idiopathic intestinal pseudo-obstruction: a surgical approach. Ann Surg 1980;192:752-61. CrossrefMedlineGoogle Scholar17. SMITH B. The Neuropathology of the Alimentary Tract. London: Edward Arnold; 1972. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: University of Pennsylvania Philadelphia, Pennsylvania PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByColonic inertia disorders in pediatricsPseudo-obstruction: Current approachesGastric emptying of mixed solid-liquid meal in patients with intestinal pseudoobstructionFamilial intestinal pseudoobstruction dominated by a progressive neurologic disease at a young ageFamilial visceral neuropathy with autosomal dominant transmissionIntestinal pseudo-obstruction--a review.Case 43-1985Pseudoobstruction of the colon complicating choriocarcinomaPseudo-obstruction and Other Obstructive DisordersCancer and Intestinal Pseudo-ObstructionF. LHERMITTE, M.D., F. GRAY, M.D., O. LYON-CAEN, M.D., B. F. PERTUISET, M.D., P. BERNARD, M.D. 1 November 1981Volume 95, Issue 5Page: 646-647KeywordsAutonomic nervous systemLesionsMuscle contractionSmooth muscles Issue Published: 1 November 1981 PDF DownloadLoading ...