ADRENAL HORMONE THERAPY IN VIRAL HEPATITIS. I. THE EFFECT OF ACTH IN THE ACUTE DISEASE
Authors: Alfred S. Evans, Helmuth Sprinz, Robert S. Nelson
Journal: Annals of Internal Medicine (1953)

Article1 June 1953ADRENAL HORMONE THERAPY IN VIRAL HEPATITIS. I. THE EFFECT OF ACTH IN THE ACUTE DISEASEALFRED S. EVANS, HELMUTH SPRINZ, ROBERT S. NELSONALFRED S. EVANSSearch for more papers by this author, HELMUTH SPRINZSearch for more papers by this author, ROBERT S. NELSONSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-38-6-1115 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe concept that adrenal cortical hormones might be beneficial in the treatment of diseases of the liver is not a new one. Eppinger suggested their use as early as 1937,1but it was not until the introduction of more purified preparations and the resurgence of interest in these hormones evolving from the work of Hench and Kendall that therapeutic trials of these agents in hepatic conditions were really begun. It has now been shown in several recent reports that these compounds exert an influence on the symptomatology ofchronicliver diseases, but that the frequency of unpleasant side effects and...Bibliography1. Eppinger H: Adrenal cortical extract in jaundiced patients, Verhandl. d. deutsch. Gesellsch. f. inn. Med., 50th Kongress Wiesbaden, 264-265, 1938. Google Scholar2. ButtComfortPowerMason HRMWMHHL: Observations on the effect of cortisone acetate on two patients with hepatitis disease, J. Lab. and Clin. Med. 37: 870-884, 1951. MedlineGoogle Scholar3. BongiovanniEisenmenger AMWJ: Adrenal cortical metabolism in chronic liver disease, J. Clin. Endocrinol. 2: 152-172 (Feb.) 1951. CrossrefGoogle Scholar4. BongiovanniBlondheimEisenmengerKunkel AMSHWJWJ: Effect of ACTH in patients with liver diseases, J. Clin. Investigation 29: 798, 1950. MedlineGoogle Scholar5. 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Med. 13: 58-72, 1952. CrossrefMedlineGoogle Scholar24. Hain K: Circulating eosinophils in health and disease, Pediatrics 7: 408-414, 1951. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication December 2, 1952.From the Hepatitis Center, 98th General Hospital, U. S. Army, Europe.†Present address: Department of Preventive Medicine and Student Health, University of Wisconsin, School of Medicine, Madison, Wisconsin. 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THE EFFECT OF ACTH AND CORTISONE IN SEVERE AND FULMINANT CASES*ALFRED S. EVANS, HELMUTH SPRINZ, ROBERT S. NELSON 1 June 1953Volume 38, Issue 6Page: 1115-1133KeywordsAdrenocorticotropic hormoneChronic liver diseaseHepatitisHepatitis DHepatitis EHormonal therapyHormonesLiver diseasesPreventive medicineSurgeons ePublished: 1 December 2008 Issue Published: 1 June 1953 Copyright & PermissionsCopyright, 1953, by The American College of PhysiciansPDF downloadLoading ...