The Prognostic Significance of Proteinuria in Young College Students
Authors: JOHN I. LEVITT
Journal: Annals of Internal Medicine (1967)

Article1 April 1967The Prognostic Significance of Proteinuria in Young College StudentsJOHN I. LEVITT, M.D.JOHN I. LEVITT, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-66-4-685 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe prognostic significance of proteinuria when discovered incidentally in asymptomatic young adults remains unknown. When other evidence of renal disease such as an abnormal urinary sediment, hypertension, or elevation of the blood urea nitrogen (BUN) and creatinine is present, then the proteinuria becomes merely one manifestation of diffuse kidney malfunction and the prognosis becomes that of the underlying renal disease.Isolated proteinuria is a more difficult problem. Earlier investigators distinguished between constant proteinuria, which they considered indicative of underlying renal disease and, therefore, a bad prognostic omen, and intermittent proteinuria, which they felt was almost universally a benign condition. However,...References1. Vital Statistics of the United States 1963, Mortality, vol. 2, pt. A. U. S. Department of Health, Education, and Welfare, Washington, D. C., 1965, section 5, p. 7. Google Scholar2. Actuarial Society of America, Transactions, vol. 42, 1941, p. 182. Google Scholar3. Society of Actuaries, Transactions, vol. 2, pt. 3. University of Chicago Press, Chicago, 1950, p. 508. Google Scholar4. Society of Actuaries, Transactions; 1962 Reports of Mortality and Morbidity Experience. University of Chicago Press, Chicago, 1963, p. 48. Google Scholar5. MACLEAN H: Albuminuria and war nephritis among British troops in France. Med. Res. Counc. Spec. Rep. (London) No. 43, 1919. Google Scholar6. LEE RI: Albuminuria in young men. Med. Clin. N. Amer. 3: 1059, 1920. Google Scholar7. FOX RH: Adolescent albuminuria in relation to life assurance. Lancet 1: 116, 1921. Google Scholar8. PALMER RS: Functional albuminuria. JAMA 96: 1559, 1931. CrossrefGoogle Scholar9. THORPEWAKEFIELD EGEG: Orthostatic albuminuria, a comparison with other types of albuminuria. Ann. Intern. Med. 6: 1565, 1933. LinkGoogle Scholar10. BASHFORD HH: Albuminuria in adolescence. Practitioner 135: 272, 1935. Google Scholar11. YOUNGHAINESPRINCE HHJSCL: Orthostatic albuminuria: the importance of its recognition by medical examining boards. Milit. Med. 92: 353, 1943. CrossrefGoogle Scholar12. WOLMAN IJ: The incidence, causes, and intermittency of proteinuria in young men. Amer. J. Med. Sci. 210: 86, 1945. CrossrefGoogle Scholar13. FISHBERG AM: Hypertension and Nephritis, 5th ed. Lea & Febiger, Philadelphia, 1954, chap. 14. Google Scholar14. DIEHLMCKINLAY HSCA: Albuminuria in college men. Arch. Intern. Med. (Chicago) 49: 45, 1932. CrossrefGoogle Scholar15. DUBLIN LI: The significance of albumin and of albumin with casts in the urine. Amer. J. Hyg. 1: 301, 1921. Google Scholar16. EVERS FC: The significance of albuminuria (abstract). Proc. Ass. Life Insur. Med. Dir. Amer. 22: 8, 1935. Google Scholar17. CHRISTIERNINDUBLINMARKS CLLIHH: A mortality study of applicants for insurance showing albuminuria and casts (abstract). Proc. Ass. Life Insur. Med. Dir. Amer. 26: 160, 1940. Google Scholar18. ROBINSONGLOVERPHILLIPPILECOCQLANGELIER RRSNPJFRPR: Fixed and reproducible orthostatic proteinuria. I. Light microscopic studies of the kidney. Amer. J. Path. 39: 291, 1961. MedlineGoogle Scholar19. ROBINSONASHWORTHGLOVERPHILLIPPILECOCQLANGELIER RRCTSNPJFRPR: Fixed and reproducible orthostatic proteinuria. II. Electron microscopy of renal biopsy specimens from five cases. Ibid., p. 405. Google Scholar20. MUTH RG: Asymptomatic mild intermittent proteinuria; a percutaneous renal biopsy study. Arch. Intern. Med. (Chicago) 115: 569, 1965. CrossrefMedlineGoogle Scholar21. LECOCQMCPHAULROBINSON FRJJRR: Fixed and reproducible orthostatic proteinuria. V. Results of a 5-year follow-up evaluation. Ann. Intern. Med. 64: 557, 1966. LinkGoogle Scholar22. KING SE: Albuminuria (proteinuria) in renal diseases. II. Preliminary observations on the clinical course of patients with orthostatic albuminuria. New York J. Med. 59: 825, 1959. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: JOHN I. LEVITT, M.D.Affiliations: Minneapolis, MinnesotaFrom the Department of Medicine, University of Minnesota Medical School, Minneapolis, Minn.This study was supported by grant 64-G-11, American Heart Association, Inc., New York, and by grant HE 08775, National Institutes of Health, Bethesda, Md.Requests for reprints should be addressed to John I. Levitt, M.D., Box 240, University of Minnesota Hospitals, Minneapolis, Minn. 55455. 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ROBINSON, M.D., F.A.C.P.The Medical Evaluation and Risk Estimation of End Stage Renal Disease for Living Kidney DonorsARE PROTEINURIA TESTS RELIABLE AS SCREENING METHODS FOR RENAL DISEASE?FOUR YEARS‘ FOLLOW UP OF ASYMPTOMATIC ISOLATED PROTEINURIA DIAGNOSED IN A GENERAL HEALTH SURVEY 1 April 1967Volume 66, Issue 4Page: 685-696KeywordsBlood urea nitrogenHypertensionLongitudinal studiesPrevention, policy, and public healthProteinsProteinuriaRenal analysisRenal diseasesStatistical dataYoung adults ePublished: 1 December 2008 Issue Published: 1 April 1967 PDF downloadLoading ...