Rapid Identification of Pathogens in Blood
Authors: Volkhard A.J. Kempf, Karlheinz Trebesius, Ingo B. Autenrieth
Journal: Annals of Internal Medicine (2000)

Letters15 February 2000Rapid Identification of Pathogens in BloodVolkhard A.J. Kempf, MD, Karlheinz Trebesius, PhD, and Ingo B. Autenrieth, MDVolkhard A.J. Kempf, MDLudwig Maximilians Universität München; D-80336 Munich, Germany (Kempf)Ludwig Maximilians Universität München; D-80336 Munich, Germany (Trebesius)Ludwig Maximilians Universität München; D-80336 Munich, Germany (Autenrieth)Search for more papers by this author, Karlheinz Trebesius, PhDLudwig Maximilians Universität München; D-80336 Munich, Germany (Kempf)Ludwig Maximilians Universität München; D-80336 Munich, Germany (Trebesius)Ludwig Maximilians Universität München; D-80336 Munich, Germany (Autenrieth)Search for more papers by this author, and Ingo B. Autenrieth, MDLudwig Maximilians Universität München; D-80336 Munich, Germany (Kempf)Ludwig Maximilians Universität München; D-80336 Munich, Germany (Trebesius)Ludwig Maximilians Universität München; D-80336 Munich, Germany (Autenrieth)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-132-4-200002150-00025 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:The sepsis syndrome is one of the leading causes of death in hospitalized patients. The mortality rate of septicemic patients ranges from 30% to 70% and depends on the pathogen that causes the septicemia and on host factors, such as age and underlying disease. Most cases of septicemia are caused by a limited number of pathogens, including Staphylococcus species, Streptococcus species, Enterococcus species, Enterobacteriaceae, Pseudomonas aeruginosa, and Candida species (1). Rapid identification of the causative pathogen in septicemia is crucial for selecting appropriate antimicrobial agents, avoiding unnecessary treatment of typical contaminants, achieving improved susceptibility to antibiotics, improving ...References1. Vincent JL, Bihari DJ, Suter PM, Bruining HA, White J, Nicolas-Chanoin MH, et al . The prevalence of nosocomial infection in intensive care units in Europe. Results of the European Prevalence of Infection in Intensive Care (EPIC) Study. EPIC International Advisory Committee. JAMA. 1995;274:639-44. CrossrefMedlineGoogle Scholar2. White AC, Atmar RL, Wilson J, Cate TR, Stager CE, Greenberg SB. Effects of requiring prior authorization for selected antimicrobials: expenditures, susceptibilities, and clinical outcomes. Clin Infect Dis. 1997;25:230-9. CrossrefMedlineGoogle Scholar3. Souvenir D, Anderson DE, Palpant S, Mroch A, Askin S, Anderson J, et al . Blood cultures positive for coagulase-negative staphylococci: antisepsis, pseudobacteremia, and therapy of patients. J Clin Microbiol. 1998;36:1923-6. CrossrefMedlineGoogle Scholar4. Amann RI, Ludwig W, Schleifer KH. Phylogenetic identification and in situ detection of individual microbial cells without cultivation. Microbiol Rev. 1995;59:143-69. CrossrefMedlineGoogle Scholar5. Trebesius K, Harmsen D, Rakin A, Schmelz J, Heesemann J. Development of rRNA-targeted PCR and in situ hybridization with fluorescently labelled oligonucleotides for detection of Yersinia species. J Clin Microbiol. 1998;36:2557-64. CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Ludwig Maximilians Universität München; D-80336 Munich, Germany (Kempf)Ludwig Maximilians Universität München; D-80336 Munich, Germany (Trebesius)Ludwig Maximilians Universität München; D-80336 Munich, Germany (Autenrieth) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDirect matrix-assisted laser desorption ionization time-of-flight mass spectrometry and real-time PCR in a combined protocol for diagnosis of bloodstream infections: a turnaround time approachApplications of Fluorescence In Situ Hybridization in Diagnostic MicrobiologyInfection of human CD34+ progenitor cells with Bartonella henselae results in intraerythrocytic presence of B henselae 15 February 2000Volume 132, Issue 4Page: 330-331KeywordsAntimicrobialsBloodEnterococcusFluorescence in situ hybridizationOligonucleotidesPathogensResearch laboratoriesSepsisStaphylococcus aureusStreptococcus ePublished: 15 August 2000 Issue Published: 15 February 2000 Copyright & PermissionsCopyright © 2000 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...