Second Primary Colorectal Cancer: The Consequence of Management Failure at Several Potential Levels
Authors: Paul J. Limburg, David A. Ahlquist
Journal: Annals of Internal Medicine (2002)

Editorials19 February 2002Second Primary Colorectal Cancer: The Consequence of Management Failure at Several Potential LevelsPaul J. Limburg, MD, MPH and David A. Ahlquist, MDPaul J. Limburg, MD, MPHFrom Mayo Clinic; Rochester, MN 55905.Search for more papers by this author and David A. Ahlquist, MDFrom Mayo Clinic; Rochester, MN 55905.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-136-4-200202190-00013 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Patients with previously diagnosed colorectal cancer are thought to be at increased risk for second primary large-bowel cancer (1-3). Widely endorsed surveillance guidelines promote regular colonoscopic evaluations after initial cancer resection in this high-risk group (4, 5). Given the generally accepted progression from adenoma to carcinoma, an effective surveillance strategy would identify and remove both preinvasive and early invasive neoplasms so that cancer might be prevented or detected before metastasizing. However, few data have been available to evaluate the effectiveness of current approaches to postoperative surveillance in reducing the risk for and from subsequent colorectal cancer.In this issue, Green ...References1. Hemminki K, Li X, Dong C. Second primary cancers after sporadic and familial colorectal cancer. Cancer Epidemiol Biomarkers Prev. 2001;10:793-8. [PMID: 11440965] MedlineGoogle Scholar2. Yamazaki T, Takii Y, Okamoto H, Sakai Y, Hatakeyama K. What is the risk factor for metachronous colorectal carcinoma? Dis Colon Rectum. 1997;40:935-8. [PMID: 9269810] CrossrefMedlineGoogle Scholar3. Enblad P, Adami HO, Glimelius B, Krusemo U, Påhlman L. The risk of subsequent primary malignant diseases after cancers of the colon and rectum. 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Gastrointest Endosc Clin N Am. 2000;10:135-60 viii. [PMID: 10618459] CrossrefMedlineGoogle Scholar12. Rex DK, Cutler CS, Lemmel GT, Rahmani EY, Clark DW, Helper DJ, et al . Colonoscopic miss rates of adenomas determined by back-to-back colonoscopies. Gastroenterology. 1997;112:24-8. [PMID: 8978338] CrossrefMedlineGoogle Scholar13. Bensen S, Mott LA, Dain B, Rothstein R, Baron J. The colonoscopic miss rate and true one-year recurrence of colorectal neoplastic polyps. Polyp Prevention Study Group. Am J Gastroenterol. 1999;94:194-9. [PMID: 9934755] CrossrefMedlineGoogle Scholar14. Rembacken BJ, Fujii T, Cairns A, Dixon MF, Yoshida S, Chalmers DM, et al . Flat and depressed colonic neoplasms: a prospective study of 1000 colonoscopies in the UK. Lancet. 2000;355:1211-4. [PMID: 10770302] CrossrefMedlineGoogle Scholar15. Lynch HT, Smyrk T, Jass JR. Hereditary nonpolyposis colorectal cancer and colonic adenomas: aggressive adenomas? Semin Surg Oncol. 1995;11:406-10. [PMID: 8607009] CrossrefMedlineGoogle Scholar16. Ahlquist DA. Aggressive polyps in hereditary nonpolyposis colorectal cancer: targets for screening. [Editorial]. Gastroenterology. 1995;108:1590-2. [PMID: 7729653] CrossrefMedlineGoogle Scholar17. Fajobi O, Yiu CY, Sen-Gupta SB, Boulos PB. Metachronous colorectal cancers. Br J Surg. 1998;85:897-901. [PMID: 9692559] CrossrefMedlineGoogle Scholar18. Fante R, Roncucci L, Di Gregorio C, Tamassia MG, Losi L, Benatti P, et al . Frequency and clinical features of multiple tumors of the large bowel in the general population and in patients with hereditary colorectal carcinoma. Cancer. 1996;77:2013-21. [PMID: 8640664] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Mayo Clinic; Rochester, MN 55905.Current Author Addresses: Drs. Limburg and Ahlquist: Division of Gastroenterology and Hepatology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoSurveillance for Second Primary Colorectal Cancer after Adjuvant Chemotherapy: An Analysis of Intergroup 0089 Robert J. Green , Joshua P. Metlay , Kathleen Propert , Paul J. Catalano , John S. Macdonald , Robert J. Mayer , and Daniel G. Haller Metrics Cited byColonoscopy surveillance after colorectal cancer resection: recommendations of the US multi-society task force on colorectal cancerColonoscopy Surveillance after Colorectal Cancer Resection: Recommendations of the US Multi-Society Task Force on Colorectal CancerColonoscopy Surveillance After Colorectal Cancer Resection: Recommendations of the US Multi-Society Task Force on Colorectal CancerQ&A on diagnosis, screening and follow-up of colorectal neoplasiaPRACTICE PATTERNS FOR SURVEILLANCE FOLLOWING COLORECTAL CANCER RESECTION 19 February 2002Volume 136, Issue 4Page: 335-337KeywordsAdenomasAdjuvant chemotherapyCohort studiesColonColonoscopyColorectal cancerHereditary nonpolyposis colorectal cancerPolypectomiesSurgical resectionSurveillance Epidemiology and End Results ePublished: 19 February 2002 Issue Published: 19 February 2002 Copyright & PermissionsCopyright © 2002 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...