Limitations of Virtual Colonoscopy
Authors: Perry J. Pickhardt
Journal: Annals of Internal Medicine (2005)

Letters18 January 2005Limitations of Virtual ColonoscopyPerry J. Pickhardt, MDPerry J. Pickhardt, MDFrom University of Wisconsin Medical School, Madison, WI 53792-3252.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-142-2-200501180-00023 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:The “new” data presented by Drs. Hwang and Wong can be readily obtained from Table 3 of our original publication (1) and are therefore not a revelation. Although our more recent study actually focused on OC and not VC performance, I would nonetheless like to respond to Drs. Hwang and Wong's comments about the positive predictive value of VC. It is important to note that these numbers reflect only adenomatous polyps. Since neither VC nor OC is specific for polyp histology, perhaps it is unfair to count nonadenomatous lesions (such as hyperplastic polyps) as false-positive results. By applying ...References1. Pickhardt PJ, Choi JR, Hwang I, Butler JA, Puckett ML, Hildebrandt HA, et al. Computed tomographic virtual colonoscopy to screen for colorectal neoplasia in asymptomatic adults. N Engl J Med. 2003;349:2191-200. [PMID: 14657426] CrossrefMedlineGoogle Scholar2. Pickhardt PJ, Choi JR, Hwang I, Schindler WR. Nonadenomatous polyps at CT colonography: prevalence, size distribution, and detection rates. Radiology. 2004;232:784-90. [PMID: 15247435] CrossrefMedlineGoogle Scholar3. Pickhardt PJ. Differential diagnosis of polypoid lesions seen at CT colonography (virtual colonoscopy). Radiographics. 2004;24:1535-56. [PMID: 15537963] CrossrefMedlineGoogle Scholar4. Barnes E. HMO pays for screening virtual colonoscopy. AuntMinnie.com. Accessed at www.auntminnie.com on 4 June 2004. Google Scholar Author, Article, and Disclosure InformationAuthors: Perry J. Pickhardt, MDAffiliations: From University of Wisconsin Medical School, Madison, WI 53792-3252. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoLocation of Adenomas Missed by Optical Colonoscopy Perry J. Pickhardt , Pamela A. Nugent , Pauline A. Mysliwiec , J. Richard Choi , and William R. Schindler Limitations of Virtual Colonoscopy Inku Hwang and Roy K.H. Wong Metrics Cited byAGA Standards for Gastroenterologists for Performing and Interpreting Diagnostic Computed Tomography Colonography: 2011 UpdateScreening for CRC Using CT ColonographyPositive predictive value for polyps detected at screening CT colonographyDiscordant Findings at CTC—Endoscopic EvaluationCT Colonography: Current Status and Future PromiseA novel retrograde-viewing auxiliary imaging device (Third Eye Retroscope) improves the detection of simulated polyps in anatomic models of the colonScreening for Colorectal Neoplasia with CT Colonography: Initial Experience from the 1st Year of Coverage by Third-Party PayersACG Colorectal Cancer Prevention Action Plan: Update On CT-Colonography 18 January 2005Volume 142, Issue 2Page: 155KeywordsAdenomasColonColonoscopyHistologyLesionsMucous membranesNegative predictive valuePositive predictive valueSpecificity ePublished: 18 January 2005 Issue Published: 18 January 2005 Copyright & PermissionsCopyright © 2005 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...