Fanconi Syndrome (Adult Type) Developing Secondary to the Ingestion of Outdated Tetracycline
Authors: JOEL M. GROSS
Journal: Annals of Internal Medicine (1963)

Case Studies1 March 1963Fanconi Syndrome (Adult Type) Developing Secondary to the Ingestion of Outdated TetracyclineJOEL M. GROSS, M.D.JOEL M. GROSS, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-58-3-523 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptLignac in 1924 described a special form of infantile rickets which seemed to be closely associated with an abnormality in cystine metabolism. Comparable observations were made by Fanconi in 1931, by de Toni in 1933, and by Debré in 1934. In 1936, Fanconi (1) concluded that in this special form of rickets a deficient reabsorption of different substances occurs in the proximal convoluted tubules of the kidney.The Lignac-Fanconi syndrome as seen in children appears to be a genetically determined disorder of renal tubular function inherited as a simple mendelian recessive characteristic, and the disorder is commonly limited to the...References1. FANCONI G: Der frühinfantile nephrotischglykosurische Zwergwuchs mit hypophosphatämischer Rachitis. Jahrb. Kinderheilk. 147: 299, 1936. Google Scholar2. STANBURY SW: Some aspects of disordered renal tubular function. Advances Intern. Med. 9: 231, 1958. MedlineGoogle Scholar3. FARHATSCHELHARTMUSSELMAN SMDLMM: Clinical toxicity of antibiotics correlated with animal studies. Arch. Surg. 76: 762, 1958. CrossrefGoogle Scholar4. SHILS ME: Some metabolic effects of tetracycline. Amer. J. Clin. Nutr. 9: 248, 1961. Google Scholar5. KUNINREESMERRILLFINLAND CMSBJPM: Persistence of antibiotics in blood of patients with acute renal failure. 1. Tetracycline and chlortetracycline. J. Clin. Invest. 38: 1487, 1959. CrossrefMedlineGoogle Scholar6. GABUZDAGOCKEJACKSONGRIGSBYDEL LOVEFINLAND GJTMGGMEBM: Some effects of antibiotics on nutrition in man. Arch. Intern. Med. (Chicago) 101: 476, 1958. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, New YorkRequests for reprints should be addressed to Joel M. Gross, M.D., Neoplastic Division, Montefiore Hospital, New York 67, New York. 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NAHIR, M.D., A. BARZILAI, M.D., D. ERLIK, M.D.Simultaneous Separation and Quantitative Determination of Tetracycline, Anhydrotetracycline, 4-Epitetracycline, and 4-Epi-anhydrotetracycline in Degraded Tetracyclines by Thin-layer ChromatographyToxic Disturbances of Renal FunctionsMetabolische Veränderungen des Säure-Basen- Haushaltes in der operativen MedizinEXPERIMENTAL RENAL TOXICITYRenal and Hepatic Injury Associated with Methoxyflurane AnesthesiaSTEPHEN G. ELKINGTON, M.D., JOHN A. GOFFINET, M.D., HAROLD O. CONN, M.D.The TetracyclinesRenal bedingte Störungen des Calcium- und Phosphatstoffwechsels. Renale OsteopathienRenale und extrarenale ausscheidung von N-pyrrolidino-methyltetracyclin (Reverin�) bei Patienten mit normaler und eingeschr�nkter NierenfunktionOBG: Hazards of Antimicrobial Therapy to Mother and FetusUntoward ReactionsRecent Developments in the Management and Prognosis of Some Inborn Errors of MetabolismRenal tubular acidosis after cadaver kidney homotransplantationQuantitative Determination by Thin-Layer Chromatography of Anhydrotetracyclines in Degraded Tetracycline TabletsComplications of tetracycline therapyWater and Electrolyte Disturbances in Cancer PatientsLong-term study of family with Fanconi syndrome without cystinosis (Detoni-Debré-Fanconi syndrome)ACID-BASE DISTURBANCES IN RENAL DISEASEHypokalemic Myopathy with Myoglobinuria Associated with Licorice IngestionSeparation and Analysis of Degradation Products of Tetracycline by Gel Filtration on Sephadex G-25Environment and the KidneyPotassium-Depletion Syndrome Secondary to Nephropathy Apparently Caused by Outdated TetracyclineFatty liver of pregnancy and its relationship to tetracycline therapyToxic nephropathyAcquired Fanconi syndromefollowing degraded tetracyclineDetermination of Anhydrotetracycline and 4-Epianhydrotetracycline in a Tetracycline MixtureComplications associated with antibiotic therapyNewer Antimicrobial Agents Having Current or Potential Clinical ApplicationAnnotationsTHE THYMUS AND PREGNANCYHÆMAGGLUTINATION-INHIBITION TESTS IN THE DIAGNOSIS OF PREGNANCYTOXICITY OF TETRACYCLINESToxicity of Tetracyclines 1 March 1963Volume 58, Issue 3Page: 523-528KeywordsCalciumChildrenExcretionIngestionKidneysNauseaProteinuriaTetracyclinesUreaUric acid Issue Published: 1 March 1963 PDF DownloadLoading ...