Serum Enzyme Assays in Acute Myocardial Infarction
Authors: SAMI VISKIN
Journal: Annals of Internal Medicine (1987)

Letters and Corrections1 March 1987Serum Enzyme Assays in Acute Myocardial InfarctionSAMI VISKIN, M.D., KARIN HELLER, M.D., DAVID GHEVA, Ph.D., AVI HASSNER, M.D.SAMI VISKIN, M.D.Search for more papers by this author, KARIN HELLER, M.D.Search for more papers by this author, DAVID GHEVA, Ph.D.Search for more papers by this author, AVI HASSNER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-106-3-473 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: In a recent review Lee and Goldman (1) state that they do not recommend the use of a single cardiac enzyme assay to exclude the diagnosis of myocardial infarction in the emergency room. Because this view could be interpreted as a guideline against routine creatine kinase testing of patients with chest pain in the emergency room, we would like to comment on our experience.During a prospective study in February 1982 (2), we evaluated 252 such patients with chest pain, including 76 ultimately diagnosed as having acute myocardial infarction by the criteria of Goldman and colleagues (3)....References1. LEE T and GOLDMAN L. Serum enzyme assays in the diagnosis of acute myocardial infarction: recommendations based on a quantitative analysis. Ann Intern Med. 1986;105:221-3. LinkGoogle Scholar2. VISKIN S, HELLER K, and GHEVA D. The importance of creatine kinase determination in identifying acute myocardial infarction among patients complaining of chest pain in an emergency room. Cardiology. (In press). Google Scholar3. GOLDMAN L, WEINBERG M, and WEISBERG M. A computer-derived protocol to aid in the diagnosis of emergency room patients with acute chest pain. N Engl J Med. 1982;307:588-96. CrossrefMedlineGoogle Scholar4. POZEN M, D'AGOSTINO R, and MITCHEL J. The usefulness of a predictive instrument to reduce inappropriate admissions to the coronary-care unit. Ann Intern Med. 1980;92:238-42. LinkGoogle Scholar5. HACKETT T and CASSEM N. Factors contributing to delay in responding to the signs and symptoms of acute myocardial infarction. Am J Cardiol. 1969;24:651-8. CrossrefMedlineGoogle Scholar1. LEE T, COOK E, WEISBERG M, SARGENT R, WILSON C, and GOLDMAN L. Acute chest pain in the emergency room. Arch Intern Med. 1985;145:65-9. CrossrefMedlineGoogle Scholar2. LEE T, WEISBERG M, COOK E, DALEY K, BRAND D, and GOLDMAN L. Clinical impact of creatine kinase and creatine kinase-MB for the diagnosis of myocardial infarction in the emergency room. Arch Intern Med. (In press). Google Scholar3. GOLDMAN L. Quantitative aspects of clinical reasoning. In: BRAUNWALD E, ISSELBACHER KJ, PETERSDORF RG, WILSON JD, MARTIN JB, FAUCI AS, eds. Harrison's Principles of Internal Medicine. New York: McGraw-Hill Book Co.; 1987:5-12. Google Scholar4. RANSOHOFF D and FEINSTEIN A. Problems of spectrum and bias in evaluating the efficacy of diagnostic tests. N Engl J Med. 1978;299:926-30. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: SAMI VISKIN, M.D.; KARIN HELLER, M.D.; DAVID GHEVA, Ph.D.; AVI HASSNER, M.D.Affiliations: Tel Aviv Medical Center Tel Aviv 64239 Israel PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 March 1987Volume 106, Issue 3Page: 473-474KeywordsAcute myocardial infarctionCreatine kinaseEmergency departmentEnzyme assaysIschemiaMyocardial infarctionPatientsProspective studies ePublished: 1 December 2008 Issue Published: 1 March 1987 PDF downloadLoading ...