The Red Blood Cell Microelectrophoretic Mobility in Benign and Malignant Disorders of the Gastrointestinal Tract
Authors: WILLIAM J. GRACE
Journal: Annals of Internal Medicine (1963)

Article1 March 1963The Red Blood Cell Microelectrophoretic Mobility in Benign and Malignant Disorders of the Gastrointestinal TractWILLIAM J. GRACE, M.D., ANTONIO ROTTINO, M.D.WILLIAM J. GRACE, M.D.Search for more papers by this author, ANTONIO ROTTINO, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-58-3-414 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptPhysicians have long been seeking a relatively simple and reliable test for the differentiation between benign and malignant disease as well as a test to determine the presence or absence of malignant disease (1). Current clinical and laboratory methods are frequently disappointing.Investigation of the electrophoretic mobility of the human red blood cell in healthy persons and in patients with various diseases has been reported (2-7). These studies have led to the conclusion that a factor in the sera in certain disease states decreases the mobility of the healthy red blood cells when applied to the red blood cells of...References1. HOMBURGER F: Evaluation of diagnostic tests for cancer. Cancer 3: 143, 1950. CrossrefMedlineGoogle Scholar2. ANGERSROTTINO JA: The electrophoretic mobility of red blood cells of normal human beings. Blood 17: 119, 1961. CrossrefMedlineGoogle Scholar3. ROTTINOANGERS AJ: The electrophoretic mobility of the red blood cell during human pregnancy. Amer. J. Obstet. Gynec. 82: 1302, 1961. CrossrefMedlineGoogle Scholar4. ROTTINOANGERS AJ: The electrophoretic mobility of erythrocytes in carcinoma and other disease. Cancer Res. 21: 1445, 1961. MedlineGoogle Scholar5. ROTTINOANGERS AJ: Electrophoretic mobility of erythrocytes of normal human beings and patients with various neoplasms. Proc. New York State Ass. Public Health Lab. XLI: 9, 1961. Google Scholar6. ROTTINOANGERS AJ: Erythrocyte microelectrophoretic slowing factor in pregnancy, chronic cervicitis and neoplasia. Amer. J. Obstet. Gynec. 83: 759, 1962. CrossrefMedlineGoogle Scholar7. ROTTINOANGERS AJ: Serum factors that cause abnormal retardation of the microelectrophoretic mobility of the red cell during disease. Clin. Chem. 8: 579, 1962. CrossrefMedlineGoogle Scholar8. PONDERPONDER ERV: Electrophoretic mobility of red cells and their ghosts as observed with improved apparatus. J. Exp. Biol. 32: 175, 1955. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: WILLIAM J. GRACE, M.D.; ANTONIO ROTTINO, M.D.Affiliations: New York, New YorkFrom the Department of Medicine and the Hodgkin's Disease Research Laboratory, St. Vincent's Hospital of the City of New York.Supported by United States Public Health Service grant CY4069, The Joseph Stein Foundation, the Margaret Biddle Foundation, and the Henry Nias Foundation.Requests for reprints should be addressed to William J. Grace, M.D., The St. Vincent's Hospital, 153 West 11th Street, New York 11, New York. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byBIBLIOGRAPHY AND AUTHOR INDEX 1 March 1963Volume 58, Issue 3Page: 414-418KeywordsClinical laboratoriesGastrointestinal tractHodgkin lymphomaHospital medicineMedical servicesRed blood cellsResearch laboratories ePublished: 1 December 2008 Issue Published: 1 March 1963 PDF downloadLoading ...