Association of Hepatitis C and Diabetes Mellitus
Authors: Hilla Knobler, A. Schattner
Journal: Annals of Internal Medicine (2001)

Letters17 July 2001Association of Hepatitis C and Diabetes MellitusHilla Knobler, MD and A. SchattnerHilla Knobler, MDHebrew University Hadassah Medical School, Jerusalem; Rehovot 76100, Israel (Knobler, Schattner)Search for more papers by this author and A. SchattnerHebrew University Hadassah Medical School, Jerusalem; Rehovot 76100, Israel (Knobler, Schattner)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-135-2-200107170-00016 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Mehta and colleagues (1), in a recently published study based on data from the Third National Health and Nutrition Examination Survey (NHANES III), gave compelling evidence for the unique association between chronic hepatitis C virus (HCV) infection and diabetes mellitus. In this large cross-sectional survey, they found that HCV-positive persons who were 40 years of age or older had an adjusted odds ratio of 3.77 for type 2 diabetes mellitus compared with HCV-negative persons. Hepatitis B virus (HBV) infection did not increase the risk for type 2 diabetes mellitus. However, this study was limited by a lack ...References1. Mehta S, Brancati F, Sulkowski M, Strathdee S, Szklo M, Thomas D. Prevalence of type 2 diabetes mellitus among persons with hepatitis C virus infection in the United States. Ann Intern Med. 2000;133:592-9. [PMID: 11033586] LinkGoogle Scholar2. Kruszynska YT, McIntyre N. Carbohydrate metabolism. In: McIntyre N, Benhamou JP, Bircher J, Rizzetto M, Rodes J, eds. Oxford Textbook of Clinical Hepatology. Oxford: Oxford Univ Pr; 1991:129-43. Google Scholar3. Knobler H, Schihmanter R, Zifroni A, Fenakel G, Schattner A. Increased risk of type 2 diabetes in noncirrhotic patients with chronic hepatitis C virus infection. Mayo Clin Proc. 2000;75:355-9. [PMID: 10761489] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Hebrew University Hadassah Medical School, Jerusalem; Rehovot 76100, Israel (Knobler, Schattner) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoPrevalence of Type 2 Diabetes Mellitus among Persons with Hepatitis C Virus Infection in the United States Shruti H. Mehta , Frederick L. Brancati , Mark S. Sulkowski , Steffanie A. Strathdee , Moyses Szklo , and David L. Thomas Association of Hepatitis C and Diabetes Mellitus Robert Paris Association of Hepatitis C and Diabetes Mellitus Shruti H. Mehta , Mark S. Sulkowski , and David L. Thomas Metrics Cited byChronic hepatitis C infection is associated with insulin resistance and lipid profilesClinical features of patients with type 2 diabetes mellitus and hepatitis C infectionGlucose Abnormalities in Patients with Hepatitis C Virus Infection: Epidemiology and pathogenesisImpaired IRS-1/PI3-kinase signaling in patients with HCV: A mechanism for increased prevalence of type 2 diabetesTumor Necrosis Factor–α–Induced Insulin Resistance May Mediate The Hepatitis C Virus–Diabetes Association 17 July 2001Volume 135, Issue 2Page: 141KeywordsCirrhosisDiabetes mellitusHealth surveysHepatitis B virusHepatitis CInfectious hepatitisLiverMedical risk factorsNutritionType 2 diabetes ePublished: 17 July 2001 Issue Published: 17 July 2001 Copyright & PermissionsCopyright © 2001 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...