Corticosteroids in Severe Alcoholic Hepatitis
Authors: Martin Black, Anthony S. Tavill
Journal: Annals of Internal Medicine (1989)

Editorials1 May 1989Corticosteroids in Severe Alcoholic HepatitisMartin Black, MD, Anthony S. Tavill, MDMartin Black, MDSearch for more papers by this author, Anthony S. Tavill, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-110-9-677 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlcoholic hepatitis is the term for a clinicopathologic syndrome resulting from prolonged excessive alcohol consumption characterized by an acute or subacute clinical presentation and a distinctive appearance on liver biopsy (which can be seen also in the absence of an acute or subacute clinical presentation). The syndrome appears to be a relatively infrequent manifestation of alcohol hepatotoxicity and may occur early or late in the course of exposure to alcohol. Although most patients have or will develop a full-fledged cirrhosis, a clinically recognizable (or diagnosed) episode of alcoholic hepatitis is identified in a minority of alcoholic patients who subsequently develop...References1. HelmanTemkoNyeFallon RMSH. Alcoholic hepatitis. Natural history and evaluation of prednisolone therapy. Ann Intern Med. 1971;74:311-21. LinkGoogle Scholar2. PorterSimonPopeVolwilerFenster HFCWL. Corticosteroid therapy in severe alcoholic hepatitis. A double-blind drug trial. N Engl J Med. 1971;284:1350-5. CrossrefMedlineGoogle Scholar3. MaddreyBoitnottBedineWeberMezeyWhite WJMFER. Corticosteroid therapy of alcoholic hepatitis. Gastroenterology. 1978;75:193-9. CrossrefMedlineGoogle Scholar4. LischnerAlexanderGalambos MJJ. Natural history of alcoholic hepatitis. I. The acute disease. Am J Dig Dis. 1971;16:481-94. CrossrefMedlineGoogle Scholar5. DiehlGoodmanIshak AZK. Alcohollike liver disease in non-alcoholics. 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CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySerum C-reactive protein: A non-invasive marker of alcoholic hepatitisAlcohol-induced liver damagePentoxifylline improves short-term survival in severe acute alcoholic hepatitis: A double-blind, placebo-controlled trialInsulin and glucagon infusion in acute alcoholic hepatitis: A prospective randomized controlled trialCorticosteroids and alcoholic hepatitisIncreased Plasma Tumor Necrosis Factor in Severe Alcoholic HepatitisGeorge L.A. Bird, MB, Nick Sheron, MB, A.K. John Goka, MB, Graeme J. Alexander, MB, Roger S. Williams, MDAlcoholic Hepatitis: Pathogenesis and Approaches to TreatmentMortality in Alcoholic HepatitisChristopher M. Hughes, MDAlcohol-induced liver damageAlcohol-induced liver damage 1 May 1989Volume 110, Issue 9Page: 677-680KeywordsAlcohol consumptionAlcoholicsAlcoholsBiopsyCirrhosisHepatitis ALiver Issue Published: 1 May 1989 PDF downloadLoading ...