Long-Term Effective Antihypertensive Therapy
Authors: ROBERT C. TARAZI
Journal: Annals of Internal Medicine (1980)

Editorials1 November 1980Long-Term Effective Antihypertensive TherapyROBERT C. TARAZI, M.D.ROBERT C. TARAZI, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-93-5-771 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptHypertension poses a unique challenge to modern medicine: the problem of lifelong, daily drug therapy for an asymptomatic disease. Preventive medicine has usually dealt with intermittent vaccinations, public health measures, and general advice on diet and exercise; in conditions needing continued therapy or restrictions such as diabetes mellitus, phenylketonuria, or rheumatic heart disease, nonadherence to preventative measures has relatively rapidly led to serious symptoms and ill health. Not so for hypertension; in that condition, drug treatment for life is often based on a single physical sign (high blood pressure) rather than dictated by the patient's symptoms. These difficulties considered, the...References1. GIFFORD R. Three decades of antihypertensive therapy Clin Pharmacol Ther. 1980;28:1-5. CrossrefMedlineGoogle Scholar2. PERRYBELTONMOSES HEC. Report of Task Force I—Data Base. Recommendations for a National High Blood Pressure Program Data Base for Effective Antihypertensive Therapy. September 1, 1973. Bethesda: Department of Health, Education, and Welfare; 1973. (DHEW Publication No. [NIH] 74-593.) Google Scholar3. Report of the Joint National Committee on the Detection, Evaluation, and Treatment of High Blood Pressure: a cooperative study. JAMA. 1977;237:255-61. CrossrefMedlineGoogle Scholar4. The 1980 Report of the Joint National Commitee on Detection, Evaluation, and Treatment of High Blood Pressure. Arch Intern Med. 1980; Google Scholar5. GIFFORDTARAZI RR. Resistant hypertension: diagnosis and management. Ann Intern Med. 1978;88:661-5. LinkGoogle Scholar6. BAUERBAKERHUNYORMARSHALL GJSP. Side-effects of antihypertensive treatment: a placebo-controlled study. Clin Sci Mol Med. 1978;55:341s-4s. MedlineGoogle Scholar7. YAMORINAKADALOVENBURG YTW. Effect of antihypertensive therapy on lysine incorporation into vascular protein of the spontaneously hypertensive rat. Eur J Pharmacol. 1976;38:349-55. CrossrefMedlineGoogle Scholar8. TARAZIFERRARIODUSTAN RCH. The heart in hypertension. In: GENEST J, KOIW E, KUCHEL O, eds. Hypertension, Physiopathology and Treatment. New York: McGraw-Hill Book Co. ; 1977:738-54. Google Scholar9. CULPEPPERHUTCHEONARCHILLACUTILLETA WNRA. Left ventricular hypertrophy in juvenile hypertension. Circulation. 1979;58 (Suppl II):11-51. Abstract. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Research Division, Cleveland Clinic Foundation Cleveland, Ohio PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByFactors that contribute to resistant forms of hypertension. Pharmacological considerations.HypertonieClinical determinants and consequences of left ventricular hypertrophyPsychosocial factors influence control of moderate and severe hypertensionManagement of the Patient With Resistant Hypertension 1 November 1980Volume 93, Issue 5Page: 771-772KeywordsAntihypertensive drug therapyDietDrugsExercise therapyHypertensionPhenylketonuriaPrevention, policy, and public healthPreventive medicinePrimary hypertensionSports and exercise medicine Issue Published: 1 November 1980 PDF DownloadLoading ...