Special Uses of Cimetidine
Authors: N. DABIR VAZIRI
Journal: Annals of Internal Medicine (1978)

Letters and Corrections1 February 1978Special Uses of CimetidineN. DABIR VAZIRI, M.D., CYRIL H. BARTON, M.D., RUSSELL NESS, M.D., KHOSROW MIRAHMADI, M.D.N. DABIR VAZIRI, M.D.Search for more papers by this author, CYRIL H. BARTON, M.D.Search for more papers by this author, RUSSELL NESS, M.D.Search for more papers by this author, KHOSROW MIRAHMADI, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-88-2-266 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: We read with interest the recent article by Swartz and colleagues that described hemodialysis with a high-chloride, low-acetate dialysate as a successful treatment for metabolic alkalosis in the postoperative patient with renal failure (1).We recently treated a 37-year-old man who had suffered a gunshot wound to the abdomen that required extensive abdominal surgery. The patient subsequently developed acute renal failure and a severe metabolic alkalosis that was secondary to nasogastric suctioning. Hemodialysis with a high-chloride, low-acetate dialysate was very effective in correcting the metabolic alkalosis.Before dialysis the blood pH was 7.57 and plasma bicarbonate 42...References1. SWARTZRUBINBROWNYAGERSTEINMANFRAZIER RJRHTH: Correction of postoperative metabolic alkalosis and renal failure by hemodialysis. Ann Intern Med 86:52-55, 1977 LinkGoogle Scholar2. BRIMBLECOMBEDUNCAN RW: The relevance to man of pre-clinical data for Cimetidine, in Proceedings of the Second International Symposium on Histamine H2-Receptor Antagonists. Amsterdam, Excerpta Medica, 1977, pp. 54-65 Google Scholar3. GILBERTBANK OS: Basal acid output response to cimetidine in man, in Proceedings of the Second International Symposium on Histamine H2-Receptor Antagonists. Amsterdam, Excerpta Medica, 1977, pp. 110-119 Google Scholar1. LONGSTRETHGOMALEGELADA GVJ: Cimetidine suppression of nocturnal gastric acid secretion in active duodenal ulcer. N Engl J Med 294:801-804, 1976 CrossrefMedlineGoogle Scholar2. WILSONGIBSONPERCINELALIBAKERLEBLANCLUCAS RDAMGLC: Severe alkalosis in critically ill surgical patients. Arch Surg 105:197-203, 1972 CrossrefMedlineGoogle Scholar3. SWARTZRUBINBROWNYAGERSTEINMANFRAZIER RJRHTH: Correction of postoperative metabolic alkalosis and renal failure by hemodialysis. Ann Intern Med 86:52-55, 1977 LinkGoogle Scholar1. WYNNEMODELL JJ: Respiratory aspiration of stomach contents. Ann Intern Med 87:466-474, 1977 LinkGoogle Scholar2. HIRSCHOWITZ B: Histamine H-2 receptor antagonists. Ann Intern Med 87:373-375, 1977 LinkGoogle Scholar3. HENNISENBERGMAXWELLSTURDEVANT RJVR: Inhibition of gastric acid secretion by cimetidine in patients with duodenal ulcer. N Engl J Med 293:371-315, 1975 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: N. DABIR VAZIRI, M.D.; CYRIL H. BARTON, M.D.; RUSSELL NESS, M.D.; KHOSROW MIRAHMADI, M.D.Affiliations: University of California Irvine Medical Center Orange, CA 92668 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPrevention and Management of Metabolic AlkalosisPrevention of metabolic alkalosis induced by gastric fluid loss using H2 receptor antagonistEffects of Cimetidine on Parathyroid Hormone in Chronic Uremia 1 February 1978Volume 88, Issue 2Page: 266-267KeywordsAbdominal surgeryAcute renal failureBicarbonatesBlood plasmaFirearm injuriesMedical dialysisRenal failure ePublished: 1 December 2008 Issue Published: 1 February 1978 PDF downloadLoading ...