Escherichia coli and Acute Diarrheal Disease
Authors: R. BRADLEY SACK
Journal: Annals of Internal Medicine (1981)

Editorial Notes1 January 1981Escherichia coli and Acute Diarrheal DiseaseR. BRADLEY SACK, M.D. SC.D.R. BRADLEY SACK, M.D. SC.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-94-1-129 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlthoughEscherichia colistrains are recognized as the commonest facultative bacteria in the normal fecal flora and as highly virulent opportunistic pathogens when outside their normal ecologic niche, their importance in the production of actue diarrheal disease has not been appreciated until recently. Until about 10 years ago,E. colistrains were related to diarrheal disease only as enteropathogenic serotypes, known to cause nursery outbreaks of infantile diarrhea and thought to be of no importance in adult diarrheal disease. This concept has now drastically changed. There has been a tremendous expansion of knowledge of the role ofE. colias...References1. Escherichia coli diarrhea. Bull WHO. 1980;58:23-36. MedlineGoogle Scholar2. SMITHHALLS HS. Studies on Escherichia coli enterotoxin. J Pathol Bacteriol. 1967;93:531-43. CrossrefMedlineGoogle Scholar3. SACKGORBACHBANWELLJACOBSCHATTERJEEMITRA RSJBBR. Enterotoxigenic Escherichia coli isolated from patients with severe cholera-like disease. J Infect Dis. 1971;123:378-85. CrossrefMedlineGoogle Scholar4. FIELD M. Modes of action of enterotoxins from Vibrio cholerae and Escherichia coli. Rev Infect Dis. 1979;1:918-25. CrossrefMedlineGoogle Scholar5. SACKKAMINSKYSACK DDR. Prophylactic doxycycline for travelers' diarrhea: results of a prospective double-blind study of Peace Corps volunteers in Kenya. N Engl J Med. 1978;298:758-63. CrossrefMedlineGoogle Scholar6. SACKFROEHLICHZULICH RJA. Prophylactic doxycycline for travelers' diarrhea: results of a prospective double-blind study of Peace Corps volunteers in Morocco. Gastroenterology. 1979;76:1368-73. CrossrefMedlineGoogle Scholar7. DUPONTSULLIVANEVANS HPD. Prevention of travelers' diarrhea (emporiatric enteritis): prophylactic administration of subsalicylate bismuth. JAMA. 1980;243:237-41. CrossrefMedlineGoogle Scholar8. ROSENBERGKOPLANWACHSMUTH MJI. Epidemic diarrhea at Crater Lake from enterotoxigenic Escherichia coli: a large water-borne outbreak. Ann Intern Med. 1977;86:714-8. LinkGoogle Scholar9. PIERCEHIRSCHHORN NN. Oral fluid—a simple weapon against dehydration in diarrhoea: how it works and how to use it. WHO Chron. 1977;31:87-93. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Departments of Medicine The Johns Hopkins University School of Medicine and Baltimore City Hospitals Baltimore, Maryland PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByEffective Treatment of Diarrhoeal Dehydration with an Oral Rehydration Solution Containing CitrateSeroepidemiology of heat-labile enterotoxigenic Escherichia coli and Norwalk virus infections in Panamanians, Canal Zone residents, Apache Indians, and United States Peace Corps volunteersTraveller's DiarrhoeaT LymphocytesEnterotoxigenic Escherichia coli: incidence in Madrid 1 January 1981Volume 94, Issue 1Page: 129-130KeywordsBacteriaDiarrheaDysenteryEscherichia coliOpportunistic pathogens Issue Published: 1 January 1981 PDF DownloadLoading ...