The Impact of Chronic Circulatory Impairment on Functioning of Central Nervous System
Authors: PAUL KEZDI
Journal: Annals of Internal Medicine (1965)

Article1 January 1965The Impact of Chronic Circulatory Impairment on Functioning of Central Nervous SystemPAUL KEZDI, M.D., MISHA S. ZAKS, PH.D., H. JOAN COSTELLO, M.S., BENJAMIN BOSHES, M.D., PH.D.PAUL KEZDI, M.D.Search for more papers by this author, MISHA S. ZAKS, PH.D.Search for more papers by this author, H. JOAN COSTELLO, M.S.Search for more papers by this author, BENJAMIN BOSHES, M.D., PH.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-62-1-67 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptA number of authors have observed that cardiac dysfunctions, particularly mitral and aortic valve deformities, are frequently associated with neurologic symptoms (1-3). Clinical observations of minor neurologic dysfunctions involve, among other signs, complaints of dizziness, attacks of syncope, confusional episodes, and paresthesias. The exact causes of these symptoms, however, are not usually assessed with any degree of accuracy.Several authors have found a relationship between mitral valve disease and central nervous system impairments, particularly cerebral embolism. In cases of cerebral embolism, Carter (4) observed 52% having mitral stenosis with atrial arrhythmia and 8% having stenosis with sinus rhythm. The frequency...References1. COSTERO I: Cerebral lesions responsible for death of patients with active rheumatic fever. Arch. Neurol. Psychiat. (Chicago) 62: 48, 1949. CrossrefMedlineGoogle Scholar2. ELLIS FH: Systemic arterial embolization accompanying mitral commissurotomy. Proc. Mayo Clin. 32: 21, 590, 1957. Google Scholar3. ZAKSLACHMANYACORZYNSKIBOSHES MSJGB: The neuropsychiatric and psychologic significance of cerebrovascular damage (strokes) following rheumatic heart surgery. Amer. J. Cardiol. 5: 6, 1960. CrossrefGoogle Scholar4. CARTER AB: The immediate treatment of cerebral embolism. Quart. J. Med. 26: 335, 1957. MedlineGoogle Scholar5. GOTTSTEINBERNSMEIERBLOMERSCHIMMLER UAHW: Cerebrale Hamodynamic bei Kranken mit Mitralstenose und kombiniertem Mitralvitium. Klin. Wschr. 38: 1025, 1960. CrossrefMedlineGoogle Scholar6. POPPER L: Die zerebralen Insulte. Wien. Z. Inn. Med. 30: 1, 1949. MedlineGoogle Scholar7. DALEYMATTINGLY RTW: Systemic arterial embolism in rheumatic heart disease. Amer. Heart J. 42: 566, 1951. CrossrefMedlineGoogle Scholar8. JORDANSCHEIFLEYEDWARDS RACHJE: Mitral thrombosis and arterial embolism in mitral stenosis. Circulation 3: 363, 1951. CrossrefMedlineGoogle Scholar9. MURPHY JP: Cerebrovascular Disease. Year Book Publishers Inc., Chicago, 1954. Google Scholar10. BRUETSCH WL: Rheumatic brain disease: late sequel of rheumatic fever. International Congress of Psychiatry, Zurich, Switzerland. Sept. 1957. Google Scholar11. BRUETSCH WL: The late neurologic and psychiatric complications of rheumatic valvular heart disease. Excerpta Medica, International Congress Series 39: 54, 1961. Google Scholar12. EISENBERGMADISONSENSEBACH SLW: Cerebral hemodynamic and metabolic studies in patients with congestive heart failure, II. Observations in confused subjects. Circulation 21: 704, 1960. CrossrefMedlineGoogle Scholar13. PRIESTZAKSYACORZYNSKIBOSHES WMSGB: The neurologic, psychiatric, and psychologic aspects of cardiac surgery. Med. Clin. N. Amer. 155, 1957. CrossrefMedlineGoogle Scholar14. ZAKS MS: Disturbances in psychological functions and neuropsychiatric complications in heart surgery. A four-year follow-up study. Cardiology. An Encyclopedia of the Cardiovascular System, Blakiston, McGraw-Hill, New York, 1959. Google Scholar15. ZAKS MS: Longitudinal research studies of effects of heart disease and cardiac surgery on psychologic and neurologic functioning. Research Approaches to Psychiatric Problems. A Symposium, Grune & Stratton, New York, 1962. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: PAUL KEZDI, M.D.; MISHA S. ZAKS, PH.D.; H. JOAN COSTELLO, M.S.; BENJAMIN BOSHES, M.D., PH.D.Affiliations: Chicago, IllinoisFrom the Cardiovascular Research Center and the Department of Neurology and Psychiatry, Northwestern University Medical School, and Chicago Wesley Memorial Hospital, Chicago, Ill.This study was supported by a grant from the Chicago Heart Association, grant RD1371-M-P from the Vocational Rehabilitation Administration, and grants HE 04915-04 and HE 06371-02 from the U. S. Public Health Service, Bethesda, Md.Requests for reprints should be addressed to Misha S. Zaks, Ph.D., Department of Neurology and Psychiatry, Northwestern University Medical School, 303 E. Chicago Ave., Chicago, Ill. 60611. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byComplete Heart Block Presenting as Intermittent Delirium: Case Report and Review of the Literature on Cardiac Disease in the ElderlyCognitive function in patients with symptomatic dilated cardiomyopathy before and after cardiac transplantationAGING, INFORMATION PROCESSING AND FITNESS*,Cerebral Physiology of the Aged: Influence of Circulatory DisordersPsycho?reactive problems of intensive therapyPsychiatric Complications of Open-Heart Surgery 1 January 1965Volume 62, Issue 1Page: 67-79KeywordsCalciumCentral nervous systemHemodynamicsLongitudinal studiesMedical servicesMitral stenosisNeurologyPsychologyStenosisSyncope ePublished: 1 December 2008 Issue Published: 1 January 1965 PDF downloadLoading ...