Thyroxine Therapy in Hypothyroid Patients Undergoing Coronary Revascularization: A Retrospective Analysis
Authors: Ian D. Hay, Daniel S. Duick, Ronald E. Vlietstra, James D. Maloney, James R. Pluth
Journal: Annals of Internal Medicine (1981)

Brief Reports1 October 1981Thyroxine Therapy in Hypothyroid Patients Undergoing Coronary Revascularization: A Retrospective AnalysisIAN D. HAY, M.B., Ph.D., DANIEL S. DUICK, M.D., RONALD E. VLIETSTRA, M.D., JAMES D. MALONEY, M.D., JAMES R. PLUTH, M.D.IAN D. HAY, M.B., Ph.D.Search for more papers by this author, DANIEL S. DUICK, M.D.Search for more papers by this author, RONALD E. VLIETSTRA, M.D.Search for more papers by this author, JAMES D. MALONEY, M.D.Search for more papers by this author, JAMES R. PLUTH, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-95-4-456 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptHypothyroid patients with disabling angina pectoris present a difficult problem in clinical management (1). Because rapid thyroid hormone replacement can aggravate a pre-existing anginal syndrome, the current therapeutic regimen in most hypothyroid patients with anginal distress is incomplete replacement, resulting in some degree of residual hypothyroidism (2, 3). Aortocoronary bypass graft surgery has provided a means of alleviating angina pectoris, but whether hypothyroid patients should undergo cautious thyroid replacement before cardiac catheterization and bypass graft surgery remains unclear (4). To address this problem, we reviewed our experience since 1970 with hypothyroid patients who had coronary artery surgery for incapacitating angina...References1. KEATINGPARKINSELBYDICKINSON FTJL. Treatment of heart disease associated with myxedema. Prog Cardiovasc Dis. 1961;3:364-81. CrossrefMedlineGoogle Scholar2. PAINEROGERSBAXLEYRUSSELL TWWR. Coronary arterial surgery in patients with incapacitating angina pectoris and myxedema. Am J Cardiol. 1977;40:226-31. CrossrefMedlineGoogle Scholar3. LEVINE H. Compromise therapy in the patient with angina pectoris and hypothyroidism: a clinical assessment. Am J Med. 1980;69:411-8. CrossrefMedlineGoogle Scholar4. NELSONPALMERBOWYER JFA. The successful treatment of myxedema and coronary artery disease in patients intolerant of thyroid hormone. Med Arts Sci. 1974;28(3):15-22. MedlineGoogle Scholar5. SONESSHIREY FE. Cine coronary arteriography. Mod Concepts Cardiovasc Dis. 1962;31:735-8. MedlineGoogle Scholar6. JUDKINS M. Percutaneous transfemoral selective coronary arteriography. Radiol Clin North Am. 1968;6:467-92. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Mayo Clinic and Mayo Foundation Rochester, Minnesota. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byHypothyroidism and ThyroiditisGuidelines for the Treatment of Hypothyroidism: Prepared by the American Thyroid Association Task Force on Thyroid Hormone ReplacementHypothyroidismHypothyroidism and ThyroiditisHypothyroidismThyroid DisordersOPCAB and thyroidectomy in a patient with a severely compromised airwaySevere Myxedema After Cardiopulmonary BypassCardiovascular and Atherogenic Aspects of Subclinical HypothyroidismPerioperative Management of Selected Endocrine DisordersThyroid Hormone Replacement Therapy for Primary and Secondary HypothyroidismThyroid DisordersOutcome of Percutaneous Transluminal Coronary Angioplasty in Patients with Subclinical HypothyroidismHypothyroidism Diagnosis and ManagementThyroid Disease in the ElderlyCardiac function in thyroid disease: Clinical features and management considerationsCardiac Manifestations of Noncardiac DiseaseHypothyroidism Complicated by Angina Pectoris: Therapeutic ApproachesThyroid DisordersHypothyroidismAnesthetic management of a hypothyroid cardiac surgical patientThyroxine replacement therapyThyroid hormone and the cardiovascular systemRecognition and management of cardiovascular disease related to thyroid dysfunctionThyroid DisordersNoncardiac complications of open-heart surgery7 The replacement therapy problem in hypothyroidismLow ventilatory and anesthetic drug requirements during myocardial revascularization in a hypothyroid patientHypothyroidism Complicated by Angina PectorisCardiac Manifestations of Noncardiac Disease in the ElderlyHypothyroidism with angina pectorisThe Thyroid GlandHypothyroidismThyroxine replacement treatment: clinical judgment or biochemical control?Anesthesia for Patients with Coronary Artery DiseaseThe ThyroidComplications of surgery in hypothyroid patientsCardiac Manifestations of Noncardiac DiseaseDiagnosis and management of the hypothyroid patient with chest painThyroxine Therapy, Hypothyroid Patients, and Coronary RevascularizationIRWIN KLEIN, M.D., GERALD S. LEVEY, M.D.Thyroid Disorders 1 October 1981Volume 95, Issue 4Page: 456-457KeywordsAnginaCardiac surgeryCoronary arteriesCoronary revascularizationHospital medicineHypothyroidismSurgeryThyroidThyroid hormonesThyroxine Issue Published: 1 October 1981 PDF downloadLoading ...