Pleural Fluid and Peripheral Blood Lymphocyte Function in Tuberculosis
Authors: JERROLD J. ELLNER
Journal: Annals of Internal Medicine (1978)

Brief Reports1 December 1978Pleural Fluid and Peripheral Blood Lymphocyte Function in TuberculosisJERROLD J. ELLNER, M.D.JERROLD J. ELLNER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-89-6-932 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe anergy to tuberculin skin testing, sometimes noted in patients with tuberculous pleurisy, usually has been attributed to preferential sequestration of antigen reactive lymphocytes in the pleural space (1). However, this hypothesis has not been tested. Pleural effusions, in fact, contain an increased proportion of total (2) and immunoglobulin-G Fc receptor-positive (3) thymus-derived lymphocytes relative to peripheral blood, but the significance of these findings is uncertain.We compared the function of peripheral blood and pleural fluid lymphocytes in three patients with culturally documented tuberculous pleurisy. Pleural fluid leukocyte counts ranged from 700 to 7200/µl with 95% to 99% mononuclear cells....References1. STEADBATES WJ: Tuberculosis, in Harrison's Principles of Internal Medicine, 8th ed., edited by THORN GW, ADAMS RD, BRAUNWALD E, ISSELBACHER KJ, PETERSDORF RG. New York, McGraw-Hill, 1977, p. 900 Google Scholar2. PETTERSSONKLOCKARSHELLSTRÖMRISKAWANGEL TMPHA: T and B lymphocytes in pleural effusions. Chest 73:49-51, 1978 CrossrefMedlineGoogle Scholar3. MANCONIFADDACADONICORNAGLIAZACCHEOGRIFONI PMAPDV: Subpopulations of T lymphocytes in human extravascular fluids. Int Arch Allergy Appl Immunol 56:385-390, 1978 CrossrefMedlineGoogle Scholar4. ELLNERDANIEL JT: Immunosuppression by mycobacterial arabinomannan. Clin Exp Immunol, 1978, in press Google Scholar5. ELLNER J: Antigen specific suppressor adherent cells in human tuberculosis (abstract). Clin Res 26:523A, 1978 Google Scholar6. ELLNER J: Suppressor adherent cells in human tuberculosis. J Immunol, in press, 1978. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. 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Analysis of PPD-Specific Proliferative Cells from Tuberculous Pleurisy Patients and Healthy Controls with Monoclonal Antibodies Specific for Human T SubsetsBCG-induced macrophage suppression in mice: Suppression of specific and nonspecific antibody-medicated and cellular immunologic responsesTuberculosis in the 1980sTHE IMMUNOLOGY OF TUBERCULOSISCutaneous Testing in the Elderly Patient with Tuberculosis 1 December 1978Volume 89, Issue 6Page: 931-932KeywordsAnergyAntigensBloodCellsHematologic testsLymphocytesPleural effusionTuberculin ePublished: 1 December 2008 Issue Published: 1 December 1978 PDF downloadLoading ...