Pemphigus Vulgaris of the Esophagus
Authors: David R. Wood, James B. Patterson, Roy C. Orlando
Journal: Annals of Internal Medicine (1982)

Brief Reports1 February 1982Pemphigus Vulgaris of the EsophagusDAVID R. WOOD, M.D., JAMES B. PATTERSON, M.D., ROY C. ORLANDO, M.D.DAVID R. WOOD, M.D.Search for more papers by this author, JAMES B. PATTERSON, M.D.Search for more papers by this author, ROY C. ORLANDO, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-96-2-189 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptBecause skin and esophagus have in common a lining of stratified squamous epithelium, it is not surprising that certain diseases affecting this epithelium can involve both organs. Thus vesiculobullous diseases such as epidermolysis bullosa dystrophica, cicatricial pemphigoid, bullous pemphigoid, toxic epidermal necrolysis, and herpesvirus infections affect both skin and esophagus (1). In contrast, pemphigus vulgaris is almost always confined to skin and mucous membranes (2). We describe a patient with pemphigus vulgaris in whom relapse was manifested by acute esophageal involvement in the absence of the characteristic skin or mucous membrane lesions. The endoscopic and histologic characteristics of the esophageal...References1. FITZPATRICK T, ARNDT K, CLARK W, EIZEN A, VAN SCOTT E, and VAUGHAN J. Dermatology in General Medicine. New York: McGraw Hill Inc. ; 1971:589-662. Google Scholar2. LEVER W. Pemphigus and pemphigoid: a review of the advances made since 1964. J Am Acad Dermatol 1979;1:2-31. CrossrefMedlineGoogle Scholar3. HONIGSMANN H, HOLUBAR K, WOLFF K, and BEUTNER E. Immunochemical localization of in vivo bound immunoglobulins in pemphigus vulgaris epidermis. Arch Dermatol Res. 1975;254:113-20. CrossrefMedlineGoogle Scholar4. HARRIST T and MIHM M. Cutaneous immunopathology: the diagnostic use of direct and indirect immunofluorescence techniques in dermatologic disease. Hum Pathol. 1979;10:625-53. CrossrefMedlineGoogle Scholar5. JUDD K and LEVER W. Correlation of antibodies in skin and serum with disease severity in pemphigus. Arch Dermatol. 1979;115:428-32. CrossrefMedlineGoogle Scholar6. AHMED A, GRAHAM J, JORDON R, and PROVOST T. Pemphigus: current concepts. Ann Intern Med. 1980;92:396-405. LinkGoogle Scholar7. ROSENBERG F, SANDERS S, and NELSON C. Pemphigus: a 20-year review of patients treated with corticosteroids. Arch Dermatol. 1976;112:962-70. CrossrefMedlineGoogle Scholar8. GELLIS S and GLASS F. Pemphigus: a survey of one hundred and seventy patients admitted to Bellevue Hospital from 1911 to 1941. Arch Dermatol Syph. 1941;44:321-36. CrossrefGoogle Scholar9. ELLER J and KEST L. Pemphigus report of seventy-seven cases. Arch Dermatol Syph. 1941 ;44:337-44. CrossrefGoogle Scholar10. RAQUE C, STEIN K, and SAMITZ M. Pemphigus vulgaris involving the esophagus. Arch Dermatol. 1970;102:371-3. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: DAVID R. WOOD, M.D.; JAMES B. PATTERSON, M.D.; ROY C. ORLANDO, M.D.Affiliations: University of North Carolina School of Medicine Chapel Hill, North Carolina PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byEsophageal Pemphigus Vulgaris: A Rare Etiology of Upper Gastrointestinal HemorrhageEffect of Systemic Illness, Medication, Radiation, and Infection on the EsophagusSloughing esophagitis: a spectacular histologic and endoscopic disease without a uniform clinical correlationEsophageal Manifestations of Collagen Vascular and Other Systemic DiseasesThe role of upper endoscopy in identifying oesophageal involvement in patients with oral pemphigus vulgarisPemphigus vulgaris with exclusive involvement of the esophagus: case report and reviewDevelopment of oesophageal involvement in a subject with pemphigus vulgaris: a case report and review of the literaturePemphigus Vegetans Involving the EsophagusOral pemphigus: Clinical significance of esophageal involvementA Case of Pemphigus Vulgaris with Esophageal InvolvementPemphigus vulgaire de l’œsophagePemphigus Vulgaris and VegetansESOPHAGEAL MANIFESTATIONS IN AUTOIMMUNE BULLOUS DISEASESEsophageal involvement in pemphigus vulgaris: A clinical, histologic, and immunopathologic studyMPemphigus vulgaris of the esophagus in womenPemphigus vulgaris involving the esophagusBullous esophageal lesions due to co-trimoxazole: An immune-mediated process?Pemphigus Vulgaris: Clinical Features 1 February 1982Volume 96, Issue 2 Page: 189-191 Keywords Epithelium Esophagus Infectious diseases Lesions Mucous membranes Nutrition Skin infections ePublished: 1 December 2008 Issue Published: 1 February 1982 PDF downloadLoading ...