Metabolic Markers of Insulin Resistance in Overweight Persons
Authors: Ali A. Rizvi
Journal: Annals of Internal Medicine (2004)

Letters3 August 2004Metabolic Markers of Insulin Resistance in Overweight PersonsAli A. Rizvi, MDAli A. Rizvi, MDFrom University of South Carolina School of Medicine, Columbia, SC 29203.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-141-3-200408030-00021 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:McLaughlin and colleagues (1) attempted to identify metabolic markers in overweight individuals that correlate with insulin resistance and predict the development of type 2 diabetes mellitus and cardiovascular disease (CVD). As the authors themselves stated, hypertriglyceridemia and low high-density lipoprotein cholesterol levels have already been established as risk factors for CVD (2) and have been included as components of the metabolic syndrome, according to the Adult Treatment Panel III (ATP III) criteria established by the National Cholesterol Education Program (3). How do the authors' findings add to the currently accepted clinical markers? Individuals in their study who ...References1. McLaughlin T, Abbasi F, Cheal K, Chu J, Lamendola C, Reaven G. Use of metabolic markers to identify overweight individuals who are insulin resistant. Ann Intern Med. 2003;139:802-9. [PMID: 14623617] LinkGoogle Scholar2. Ballantyne CM, Olsson AG, Cook TJ, Mercuri MF, Pedersen TR, Kjekshus J. Influence of low high-density lipoprotein cholesterol and elevated triglyceride on coronary heart disease events and response to simvastatin therapy in 4S. Circulation. 2001;104:3046-51. [PMID: 11748098] CrossrefMedlineGoogle Scholar3. Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III). JAMA. 2001;285:2486-97. [PMID: 11368702] CrossrefMedlineGoogle Scholar4. Einhorn D, Reaven GM, Cobin RH, Ford E, Ganda OP, Handelsman Y, et al . American College of Endocrinology position statement on the insulin resistance syndrome. Endocr Pract. 2003;9:237-52. [PMID: 12924350] CrossrefMedlineGoogle Scholar5. Lorenzo C, Okoloise M, Williams K, Stern MP, Haffner SM. The metabolic syndrome as predictor of type 2 diabetes: the San Antonio heart study. Diabetes Care. 2003;26:3153-9. [PMID: 14578254] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Ali A. Rizvi, MDAffiliations: From University of South Carolina School of Medicine, Columbia, SC 29203. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoUse of Metabolic Markers To Identify Overweight Individuals Who Are Insulin Resistant Tracey McLaughlin , Fahim Abbasi , Karen Cheal , James Chu , Cindy Lamendola , and Gerald Reaven Metabolic Markers of Insulin Resistance in Overweight Persons Tracey McLaughlin and Gerald Reaven Metrics Cited byEffect of pioglitazone on outcome following curative treatment for hepatocellular carcinoma in patients with hepatitis C virus infection: A prospective study 3 August 2004Volume 141, Issue 3Page: 243KeywordsAdenosine triphosphateCardiovascular diseasesCholesterolHigh density lipoprotein cholesterolInsulin resistanceMedical risk factorsMetabolic syndromeOverweightType 2 diabetesWeight loss ePublished: 3 August 2004 Issue Published: 3 August 2004 Copyright & PermissionsCopyright © 2004 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...