Cancer in Ulcerative Colitis: Good News and Bad News
Authors: DAVID B. SACHAR
Journal: Annals of Internal Medicine (1981)

Editorials1 November 1981Cancer in Ulcerative Colitis: Good News and Bad NewsDAVID B. SACHAR, M.D., ADRIAN J. GREENSTEIN, M.D.DAVID B. SACHAR, M.D.Search for more papers by this author, ADRIAN J. GREENSTEIN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-95-5-642 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptMost investigators agree on two points concerning cancer in ulcerative colitis. First, the risk of colorectal cancer seems to be higher in ulcerative colitis patients than in the general population. Second, the diagnosis of colorectal cancer in ulcerative colitis is too often delayed until the tumor is far advanced and incurable; early detection or prevention would be preferable. Beyond these two predictable areas of agreement, however, however, consensus rapidly breaks down.The issues that remain in dispute fall into four broad categories: measuring the "true" incidence of cancer in ulcerative colitis; identifying those factors that influence the risk of cancer...References1. GILATZEMISHLANYRIBAKBENAROYALILOS TZJYP. Ulcerative colitis in the Jewish population of Tel-Aviv Yafo. II. The rarity of malignant degeneration. Gastroenterology. 1974;67:933-8. CrossrefMedlineGoogle Scholar2. DEVROEDETAYLORSAUERJACKMANSTICKLER GWWRG. Cancer risk and life expectancy of children with ulcerative colitis. N Engl J Med. 1971;285:17-21. CrossrefMedlineGoogle Scholar3. DEVROEDE G. Risk of cancer in inflammatory bowel disease. In: WINAWER SJ, SCHOTTENFELD D, SHERLOCK P, eds. Colorectal Cancer: Prevention, Epidemiology, and Screening. Vol. 13. New York: Raven Press; 1980:325-34. Google Scholar4. GREENSTEINSACHARSMITH ADH. 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The frequency, appearance and clinical significance of macroscopical changes associated with dysplasia and carcinoma (MADC) complicating chronic ulcerative colitis (CUC). Gastroenterology. 1981;80:1119. Abstract. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. 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