"Normotensive" Primary Aldosteronism
Authors: ROBERT D. ZIPSER
Journal: Annals of Internal Medicine (1978)

Brief Reports1 May 1978"Normotensive" Primary AldosteronismROBERT D. ZIPSER, M.D., PAUL F. SPECKART, M.D.ROBERT D. ZIPSER, M.D., PAUL F. SPECKART, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-88-5-655 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptHypokalemia and hypertension are the most important features of primary aldosteronism. In rare instances, patients with this disorder have normal serum potassium levels, but this is usually attributed to sodium restriction. Hypertension, however, has been commonly found (1-5).We describe here the case of a patient with hypokalemia, inappropriate kaliuresis, and persistently normal blood pressure. Primary aldosteronism was diagnosed by the fludrocortisone suppression test, and spironolactone therapy normalized the electrolyte imbalance.Hypokalemia was first documented in December 1975 in a 45-year-old black woman evaluated for depression. Depression worsened, and she was hospitalized in the summer of 1976 for 16 weeks....References1. HORTON R: Aldosterone: review of its physiology and diagnostic aspects of primary aldosteronism. Metabolism 22:1525-1545, 1973 CrossrefMedlineGoogle Scholar2. SPARKMELBY RJ: Aldosteronism in hypertension. The spironolactone response test. Ann Intern Med 69:685-691, 1968 LinkGoogle Scholar3. BIGLIERISCHAMBELANSLATONSTOCKIGT EMPJ: The intercurrent hypertension of primary aldosteronism. Circ Res 26 & 27 (suppl 1):I-195-I-202, 1970 Google Scholar4. BAERSOMMERSKRAKOFFNEWTONLARAGH LSLMJ: Pseudo-primary aldosteronism. An entity distinct from true primary aldosteronism. Circ Res 26 & 27 (suppl 1):1-203-I-216, 1970 Google Scholar5. CONNKNOPFNESBIT JRR: Clinical characteristics of primary aldosteronism from an analysis of 145 cases. Am J Surg 107:159-172, 1964 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: University of Southern California Los Angeles, California PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByNearly fatal hypokalaemia due to non-hypertensive primary hyperaldosteronism in the post partumPrimary Mineralocorticoid Excess Disorders and HypertensionPathophysiology, Diagnosis, and Treatment of Mineralocorticoid DisordersSubclinical primary aldosteronismShould primary aldosteronism be diagnosed among normotensive subjects during general health check-up and/or at general outpatient clinics?Primary Mineralocorticoid Excess Syndromes and HypertensionClinical and biochemical characteristics of normotensive patients with primary aldosteronism: a comparison with hypertensive casesAdrenocortical tumors: clinical symptoms and biochemical diagnosisO espectro das síndromes de hipertensão esteróide na infância e adolescênciaHiperaldosteronismo primario normotensivoDiseases of the adrenal cortexPrimary AldosteronismPrimary HyperaldosteronismBartter's SyndromePrimary AldosteronismBartter's SyndromePrimary hyperaldosteronism in childhood due to unilateral macronodular hyperplasia. Case report.Asymptomatic normotensive primary aldosteronism. Case report.Diagnostic strategies in disorders of fluid, electrolyte and acid-base homeostasis2 Primary hyperaldosteronismA Case of Normoreninemic, Normotensive Primary Aldosteronism Associated with Essential Hypertension and NephrocalcinosisNormotensive primary aldosteronismPrimary hyperaldosteronismAdrenocortical diseasesAldosterone Producing Adenoma: Fludrocortisone Suppression and Left Adrenal Vein Catheterisation in Definitive Diagnosis and Management 1 May 1978Volume 88, Issue 5Page: 655-656KeywordsBlood pressureFludrocortisoneHypertensionPotassiumSodium Issue Published: 1 May 1978 PDF DownloadLoading ...