Staphylococcus aureus Antigen in Cerebrospinal Fluid Cross-Reactive with Haemophilus influenzae Type b Antiserum
Authors: Bruce Ribner, Gerald T. Keusch, John B. Robbins
Journal: Annals of Internal Medicine (1975)

Letters1 September 1975Staphylococcus aureus Antigen in Cerebrospinal Fluid Cross-Reactive with Haemophilus influenzae Type b AntiserumBRUCE RIBNER, M.D., GERALD T. KEUSCH, M.D., JOHN B. ROBBINS, M.D.BRUCE RIBNER, M.D.Search for more papers by this author, GERALD T. KEUSCH, M.D.Search for more papers by this author, JOHN B. ROBBINS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-83-3-370 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptEtiologic diagnosis of pneumococcal, meningococcal, and Haemophilus influenzae type b meningitis can be made by counter Immunoelectrophoresis of cerebrospinal fluid (CSF) (1), which detects capsular polysaccharide antigens of the organisms. We recently observed a patient with central nervous system infection during cefazolin therapy for Staphylococcus aureus endocarditis in which cross-reacting antigen in CSF was shown by counter Immunoelectrophoresis using H. influenzae type b antiserum.A 23-year-old woman with anorexia nervosa was hospitalized for alimentation. Following admission she became comatose due to severe hypoglycemia (blood glucose, 12 mg/100 ml) responding rapidly to intravenous glucose administration.Hyperalimentation was begun through a central...References1. COONRODRYTEL JM: Determination of aetiology of bacterial meningitis by counter-immunoelectrophoresis. Lancet 1:1154-1157, 1972 CrossrefMedlineGoogle Scholar2. ARGAMANLIUROBBINS MTJ: Polyribitol-phosphate : an antigen of four gram-positive bacteria cross-reactive with the capsular polysaccharide of Haemophilus influenzae type b. J Immunol 112:649-655, 1974 MedlineGoogle Scholar3. COONRODRYTEL JM: Specificity of counter-immunoelectrophoresis in bacterial meningitis. Lancet 2:829, 1972 CrossrefMedlineGoogle Scholar4. NAGELTUAZONCARDELLA JCT: Teichoic acid serologic diagnosis of staphylococcal endocarditis. Ann Intern Med 82:13-17, 1975 LinkGoogle Scholar5. RELLERKARNEYBEATY LWH: Evaluation of cefazolin, a new cephalosporin antibiotic. Antimicrob Agents Chemother 3:488-497, 1973 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySymposium on Staphylococcal Septicaemia and Endocarditis. Lund, Sweden, March 17–18, 1983Immunoassays in MeningitisImmunodiagnosis Detection of Antigens in Body FluidsThermodissociation of staphylococcal immune complexes and detection of staphylococcal antigen in serum from patients with Staphylococcus aureus bacteremiaRapid differentiation of the major causative agents of bacterial meningitis by use of frequency-pulsed electron capture gas-liquid chromatograph: analysis of acidsPractical considerations in using counterimmunoelectrophoresis to identify the principal causative agents of bacterial meningitisTeichoic acid serology in staphylococcal infectionsof infants and childrenCorrelation of antistaphylococcal antibody titers with severity of staphylococcal diseaseTeichoic Acid Antibodies in the Diagnosis of Serious Infections with Staphylococcus aureusCARMELITA U. TUAZON, M.D., JOHN N. SHEAGREN, M.D., F.A.C.P. 1 September 1975Volume 83, Issue 3Page: 370-371KeywordsAntigensCerebrospinal fluidColony stimulating factorEndocarditisGlucoseHaemophilus influenzae type BImmunoelectrophoresisPolysaccharidesStaphylococcal infectionStaphylococcus aureus Issue Published: 1 September 1975 PDF downloadLoading ...