Immunoglobulin Replacement Therapy by Slow Subcutaneous Infusion
Authors: MELVlN BERGER
Journal: Annals of Internal Medicine (1980)

Brief Reports1 July 1980Immunoglobulin Replacement Therapy by Slow Subcutaneous InfusionMELVlN BERGER, M.D., Ph.D., THOMAS R. CUPPS, M.D., ANTHONY S. FAUCI, M.D.MELVlN BERGER, M.D., Ph.D., THOMAS R. CUPPS, M.D., ANTHONY S. FAUCI, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-93-1-55 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlcohol fractionated immune serum globulin and fresh frozen plasma are the only generally available preparations used for replacement therapy in patients with antibody deficiency syndromes. The maximal doses that may be given are limted by the generally marked discomfort of the intramuscular injections and the large volumes of plasma that are necessary (1). Although many patients can be maintained free from infections or other symptoms despite these constraints, others continue to present problems that could potentially be relieved if greater amounts of immunoglobulin could be administered (2). We report here the successful use of a small portable pump to administer...Reffrences1. STIEHM E. Plasma therapy: an alternative to gamma globulin injections in immunodeficiency. Birth Defects. 1975;11(1):343-6. MedlineGoogle Scholar2. MOLLISON P chairman). Hypogammaglobulinemia in the United Kingdom. Lancet. 1969;1:163-8. MedlineGoogle Scholar3. WALKERGAULDIE WJ. Automated determination of immunoglobulins. In: RITCHIE RF, ed. Automated Immunoanalysis. New York: Marcel Dekker; 1978:203-25. Google Scholar4. CHANDRACOOPERHITZIG RMW. Immunodeficiency: Report of a WHO Scientific Group. Clin Immunol Immunopathol. 1979;13:296-359. CrossrefMedlineGoogle Scholar5. BARANDUNKISTLERJENNETISLIKER SPFH. Intravenous administration of human gammaglobulin. Vox Sang. 1962;7:157-74. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. 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CAMPBELL, M.D., JOEL B. MASON, M.D., JOHN M. WEILER, M.D.CLINICAL USES OF HUMAN IMMUNOGLOBULINFIBRONECTIN AND INFECTIONImmune Globulin for Intravenous InfusionRALPH H. ROUSELL, M.D.A Conceptual Approach to ImmunodeficiencyImmunodeficiency in the clinic and laboratory 1 July 1980Volume 93, Issue 1_Part_1Page: 55-56KeywordsAlcoholsAntibody therapyBlood plasmaImmune serum globulinIntramuscular injections Issue Published: 1 July 1980 PDF downloadLoading ...