Recurrent Ventricular Tachycardia and Fibrillation Treated with a Combination of Beta-Adrenergic Blockade and Electrical Pacing
Authors: LAWRENCE S. COHEN
Journal: Annals of Internal Medicine (1967)

Case Studies1 May 1967Recurrent Ventricular Tachycardia and Fibrillation Treated with a Combination of Beta-Adrenergic Blockade and Electrical PacingLAWRENCE S. COHEN, M.D., ROBERT A. BUCCINO, M.D., ANDREW G. MORROW, M.D., EUGENE BRAUNWALD, M.D., F.A.C.P.LAWRENCE S. COHEN, M.D., ROBERT A. BUCCINO, M.D., ANDREW G. MORROW, M.D., EUGENE BRAUNWALD, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-66-5-945 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptParoxysmal ventricular tachycardia is most often associated with organic heart disease and in this setting is of ominous prognostic import (1-3). Less commonly, this arrhythmia occurs in young individuals without underlying heart disease; in these patients the disorder is generally considered benign (4). However, in some of these patients the episodes of paroxysmal ventricular tachycardia may lead to syncope and sudden death (2, 5). Recently, the efficacy of the beta-adrenergic blocking drugs in the treatment of tachyarrhythmias has been recognized (6, 7), and these drugs have been employed with success in certain patients with recurrent ventricular tachycardia (8-11). Electrical pacemakers...References1. STRAUSS MB: Paroxysmal ventricular tachycardia. Amer. J. Med. Sci. 179: 337, 1930. CrossrefGoogle Scholar2. ARMBRUSTLEVINE CASA: Paroxysmal ventricular tachycardia: a study of one hundred and seven cases. Circulation 1: 28, 1950. CrossrefMedlineGoogle Scholar3. LEVINEHARVEY SAWP: Clinical Auscultation of the Heart. W. B. Saunders Co., Philadelphia and London, 1959, p. 153. Google Scholar4. DIMONDHAYES EGWL: Benign paroxysmal ventricular tachycardia: report of a case. Ann. Intern. Med. 53: 1255, 1960. LinkGoogle Scholar5. MADDOX K: Intermittent ventricular tachycardia in youth. Report of case with fatal termination. Amer. Heart J. 33: 739, 1947. Google Scholar6. STOCKDALE JPN: Beta-adrenergic receptor blockade in cardiac arrhythmias. Brit. Med. J. 2: 1230, 1963. CrossrefMedlineGoogle Scholar7. HARRISONGRIFFINFIENE DCJRTJ: Effects of beta-adrenergic blockade with propranolol in patients with atrial arrhythmias. New Eng. J. Med. 273: 410, 1965. CrossrefMedlineGoogle Scholar8. BESTERMANFRIEDLANDER EMDH: Clinical experiences with propranolol. Postgrad. Med. J. 41: 526, 1965. CrossrefMedlineGoogle Scholar9. ROWLANDSHOWITTMARKMAN DJGP: Propranolol (Inderal) in disturbances of cardiac rhythm. Brit. Med. J. 1: 891, 1965. CrossrefMedlineGoogle Scholar10. SLOMANROBINSONMCLEAN GJSK: Propranolol (Inderal) in persistent ventricular fibrillation. Ibid., p. 895. Google Scholar11. TAYLORHALLIDAY RREJ: Beta-adrenergic blockade in the treatment of exercise-induced paroxysmal ventricular tachycardia. Circulation 32: 778, 1965. CrossrefMedlineGoogle Scholar12. ZOLLLINENTHALZARSKY PMAJLR: Ventricular fibrillation. Treatment and prevention by external electric currents. New Eng. J. Med. 262: 105, 1960. CrossrefMedlineGoogle Scholar13. SOWTONLEATHAMCARSON EAP: The suppression of arrhythmias by artificial pacemaking. Lancet 2: 1098, 1964. CrossrefMedlineGoogle Scholar14. SOWTON E: The use of artificial pacemaking in cardiac resuscitation. Proc. Roy. Soc. Med. 57: 368, 1964. CrossrefMedlineGoogle Scholar15. HEIMANHELWIG DFJ: Suppression of ventricular arrhythmias by transvenous intracardiac pacing. JAMA 195: 1150, 1966. CrossrefGoogle Scholar16. SCHOONMAKEROSTEENGREENFIELD FWRTJC: Thioridazine (Mellaril®)-induced ventricular tachycardia controlled with an artificial pacemaker. Ann. Intern. Med. 65: 1076, 1966. LinkGoogle Scholar17. GILBERTLANGEBROOKS JLGCM: Influence of sympathomimetic pressor drugs on arrhythmias caused by m ltiple stimuli. Circ. Res. 7: 417, 1959. CrossrefMedlineGoogle Scholar18. BECKERNONKINBENNETTKIMBALLSTERNBERGWASSERMAN DJPMLDSGMSF: Effect of isoproterenol in digitalis cardiotoxicity. Amer. J. Cardiol. 10: 242, 1962. CrossrefMedlineGoogle Scholar19. SEKIYAVAUGHAN WILLIAMS AEM: A comparison of the antifibrillatory actions and effects on intracellular cardiac potentials of pronethalol, disopyramide and quinidine. Brit. J. Pharmacol. 21: 473, 1963. Google Scholar20. LUCCHESI BR: The effects of pronethalol and its dextro isomer upon experimental cardiac arrhythmias. J. Pharmacol. Exp. Ther. 148: 94, 1965. MedlineGoogle Scholar21. GLENNMAUROLONGOLAVIETESMACKAY WWAEPHFJ: Remote stimulation of the heart by radiofrequency transmission. Clinical application to a patient with Stokes-Adams syndrome. New Eng. J. Med. 261: 948, 1959. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: LAWRENCE S. COHEN, M.D.; ROBERT A. BUCCINO, M.D.; ANDREW G. MORROW, M.D.; EUGENE BRAUNWALD, M.D., F.A.C.P.Affiliations: Bethesda, MarylandFrom the Cardiology Branch and Clinic of Surgery, National Heart Institute, National Institutes of Health, Bethesda, Md.Requests for reprints should be addressed to Eugene Braunwald, M.D., Clinical Director, National Heart Institute, National Institutes of Health, Bethesda, Md. 20014. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byCatecholaminergic Polymorphic Ventricular Tachycardia in ChildrenEffect of Atrial Pacing on the Frequency of Tachycardia in Patients with Recurrent Junctional Tachycardiaβ-Adrenergic Blockade in ChildrenVentricular tachycardia in children without heart diseaseTreatment of Life-threatening Ventricular Arrhythmias by a Combination of Antiarrhythmic Drugs and Right Ventricular PacingOverdrive Pacing for Ventricular Tachyarrhythmias: A ReassessmentPETER R. KOWEY, M.D., TOBY R. ENGEL, M.D.External Electrical Stimulation in the Management of Acute TachyarrhythmiasClinical Electrophysiology of Ventricular TachycardiaPrognosis in primary ventricular tachycardia in the pediatric patient.Current status of pacemaker therapy of arrhythmiasOral propranolol treatment in infants and childrenThe treatment of patients with recurrent ventricular fibrillationParoxysmal Ventricular Fibrillation in ChildrenSpectrum of sinus node dysfunction in two siblingsParoxysmal Ventricular Tachycardia of Unknown EtiologyIdiopathic paroxysmal ventricular tachycardia in infants and childrenTherapeutic uses of permanent pervenous atrial pacemakers: A reviewTreatment of arrhythmias by intracardiac electrical stimulationPacemaker Overdrive Causing Recurrence of Rate-Dependent Ventricular TachycardiaChronic Overdrive Pacing in the Control of Refractory Ventricular ArrhythmiasROBERT A. JOHNSON, M.D., ADOLPH M. HUTTER JR., M.D., F.A.C.P., ROMAN W. DESANCTIS, M.D., F.A.C.P., PETER M. YURCHAK, M.D., F.A.C.P., ROBERT C. LEINBACH, M.D., J. WARREN HARTHORNE, M.D., F.A.C.P.Relationship between heart rate and ventricular ectopic rhythm in acute myocardial infarctionPAROXYSMAL TACHYCARDIA IN INFANCY AND CHILDHOOD II. Paroxysmal Ventricular Tachycardia and FibrillationThe authors replyPermanent Atrial PacingTreatment of Ventricular Arrhythmias in Ambulatory PatientsPacemaker therapy for chronic rhythm disordersOverdriving by pacing to suppress ventricular ectopic activityControl of Intractable Ventricular Tachycardia by Coronary RevascularizationPacemakers and their arrhythmiasPermanent transvenous demand pacing of the heartTreatment of recurrent paroxysmal ventricular tachycardiaRecent advances in the treatment of ectopic tachycardias by electrical pacingEffects of ventricular stimulation and potassium administration on digitalis-induced arrhythmiasThe use of ventricular pacing for suppression of ectopic ventricular activityβ-ReceptorenblockerSuppression of refractory recurrent ventricular tachycardia by transvenous rapid cardiac pacing and antiarrhythmic drugsThe Effects of Propranolol on Cardiac ConductionCardiopulmonary resuscitation. Part IICardiac Pacing in the Prevention and Treatment of TachyarrhythmiasLong-term control of intractable supraventricular tachycardia by ventricular pacing.MANAGEMENT OF CARDIAC TACHYARRHYTHMIAS WITH CARDIAC PACEMAKERSELECTRICAL STIMULATION OF THE ATRIA IN PATIENTS WITH AN INTACT ATRIOVENTRICULAR CONDUCTION SYSTEMDISTURBANCES OF RHYTHM UNDERLYING ADAMS-STOKES SEIZURESLong-Term Pervenous Atrial PacingThe use of beta-adrenergic receptor blocking drugs in dysrhythmiasThe Stokes-Adams syndromeCoronary and precoronary careThe Use of procaine amide and lidocaine in the treatment of cardiac arrhythmiasPermanent Pacing in the Absence of Heart BlockGekoppelte elektrische Stimulation bei tachykarden HerzrhythmusstörungenTransvenous ventricular pacing in the treatment of paroxysmal atrial tachyarrhythmias alternating with sinus bradycardia and standstillRapid intracardiac pacing for treatment of recurrent ventricular tachyarrhythmias in the absence of heart blockTransvenous Left Atrial Pacing for the Control of Recurrent Ventricular FibrillationParoxysmal Ventricular Fibrillation in Two Patients with HypomagnesemiaAntiarrhythmic CompoundsHerzstimulation und ihre ÜberwachungRefractory Paroxysmal Ventricular TachycardiaDOUGLAS P. ZIPES, M.D., EDWARD S. ORGAIN, M.D., F.A.C.P. 1 May 1967Volume 66, Issue 5 Page: 945-949 Keywords Arrhythmia Atrial fibrillation Cardiac surgery Cardiovascular therapy Drugs Pacemakers Syncope Tachycardia Thoracic surgery Ventricular tachycardia ePublished: 1 December 2008 Issue Published: 1 May 1967 PDF downloadLoading ...