Hantavirus Antibodies in New York
Authors: Walter G. Wasser, Cindy A. Rossi, Gregory E. Glass
Journal: Annals of Internal Medicine (1997)

Letters15 July 1997Hantavirus Antibodies in New YorkWalter G. Wasser, MD, Cindy A. Rossi, MA, and Gregory E. Glass, PhDWalter G. Wasser, MDNorth General Hospital; New York. NY 10035U.S. Army Research Institute of Infectious Diseases; Frederick, MD 21701 (Rossi)Johns Hopkins School of Public Health; Baltimore, MD 21205Search for more papers by this author, Cindy A. Rossi, MANorth General Hospital; New York. NY 10035U.S. Army Research Institute of Infectious Diseases; Frederick, MD 21701 (Rossi)Johns Hopkins School of Public Health; Baltimore, MD 21205Search for more papers by this author, and Gregory E. Glass, PhDNorth General Hospital; New York. NY 10035U.S. Army Research Institute of Infectious Diseases; Frederick, MD 21701 (Rossi)Johns Hopkins School of Public Health; Baltimore, MD 21205Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-127-2-199707150-00028 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:To clarify an association between end-stage renal disease and antibodies to hantavirus [1, 2], we examined serum samples from patients seen in a dialysis facility and an emergency department in New York City.Serum samples were screened by enzyme-linked immunosorbent assay (ELISA) using previously described protocols [1]. To confirm the ELISA results, a Western blot analysis of tentatively positive samples was done. Samples with antibodies directed against nucleocapsid protein [3] were considered seropositive.Of 546 samples screened by ELISA, 292 were controls obtained from the emergency department population and 254 were obtained from patients undergoing hemodialysis. Overall, ...References1. Glass GE, Watson AJ, LeDuc JW, Kelen GD, Quinn TC, Childs JE. Infection with a ratborne hantavirus in US residents is consistently associated with hypertensive renal disease. J Infect Dis. 1993; 167:614-20. Google Scholar2. Peter JB, Patnaik M, Gott P, Weins B, Souw PT. Antibodies to different strains of hantavirus in end-stage renal disease in USA and Japan. Lancet. 1994; 343:181. Google Scholar3. Schmaljohn CS, Jennings GB, Jay J, Dalrymple JM. Coding strategy of the S genome segment of hanta virus. Virology. 1986:155:633-43. Google Scholar4. Kleinknecht D, Rolin PE. Hypertension after hemorrhagic fever with renal syndrome. Nephron. 1993; 61:121. Google Scholar Author, Article, and Disclosure InformationAffiliations: North General Hospital; New York. NY 10035U.S. Army Research Institute of Infectious Diseases; Frederick, MD 21701 (Rossi)Johns Hopkins School of Public Health; Baltimore, MD 21205 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByZoonotic and Vector-Borne Infections Among Urban Homeless and Marginalized People in the United States and Europe, 1990–2014Emergency Medicine and the Public's Health: Emerging Infectious DiseasesTropical dermatology: viral tropical diseases 15 July 1997Volume 127, Issue 2Page: 166-167KeywordsAntibodiesEmergency departmentEnzyme linked immunosorbent assayMedical dialysisOdds ratioProspective studiesProteinsRenal diseasesRenal failureWestern blot Issue Published: 15 July 1997 CopyrightCopyright © 1997 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...