tbuckley/cabot-search huggingface dataset:
Notes on an Outbreak of Influenza at King Edward's Schools for Girls
Authors: H. C. Bristowe
Journal: BMJ (1890)

infection is near, and within a few hours-much too short a time for an incubation period-several case8 appear.Very few people can give any more definite account of how, when, or from whom they caught the infection than the man-in-the-street source-a circumsltance that is not usually observed in case of other con- tagious disorders.In this prison epidemic none of the patients already in hospital contracted the disease, although men in various stages of influenza, to the number of twenty, passed through the wards between January 2nd and FebruaTy let.At the same time three hospital orderlies out of four, who were moving about and taking exercise daily out of doors, were struck down at the beginning of the epi- demic, and suffered rather severely.If it be true, as held by some, that the virus is iven off in the breath of the patient, we have pretty strong evilence that this virus does not live long, or show such tenacity as the germs of
Chemotherapeutic Agents for the Systemic Mycoses
Authors: John P. Utz
Journal: New England Journal of Medicine (1963)

DURING the past seven years there has been a sustained increase of interest in the treatment of the systemic mycoses, an interest nurtured both by successful advances in therapy and by the emergence of new diseases. Two new antifungous antibiotics, amphotericin B and X-5079C, each of which is effective against a variety of fungous infections in laboratory animals and in man, have appeared. With the former drug a disease, cryptococcal meningitis, universally fatal in the past, has been successfully treated in at least 60 per cent of patients. An older drug (2-hydroxystilbamidine) has been carefully studied in an impressive number . . .
Specialty of Chest Medicine
Authors: W. H. Tattersall
Journal: BMJ (1964)

C3a and C5a were investigated for their ability to induce secretion of serotonin from platelets in a homologous guinea pig system. Platelets respond to either anaphylatoxin with a dose-dependent release that does not exceed a plateau at the 70% level. On a molar basis. C5a is about 50-fold more active than the C3 fragment. The C5a effects in the platelet system can be clearly distinguished from the activity of C3a and vice versa by a phenomenon of specific desensitization of the platelets to either stimulus. Our observations lead to the postulation of distinct receptors for C3a and C5a on guinea pig platelets as well as 2 independent pathways of platelet activation, which both lead to a specific release.
Are the Harms of False-Positive Screening Test Results Minimal or Meaningful?
Authors: Kurt Kroenke
Journal: JAMA Internal Medicine (2014)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Internal Medicine HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Internal Medicine journal
Effect of serum phosphate on parathyroid hormone secretion during hemodialysis
Authors: Angel L.M. de Francisco, Maria A. Cobo, Maria A. Setien, Emilio Rodrigo, Gema F. Fresnedo, Maria T. Unzueta, Jose A. Amado, J. Carlos Ruiz, Manuel Arias, Mariano Rodriguez
Journal: Kidney International (1998)
Recurrence of focal glomerulosclerosis despite cyclosporin treatment after renal transplantation.
Authors: Y Pirson, J P Squifflet, E Marbaix, G P Alexandre, C van Ypersele de Strihou
Journal: BMJ (1986)

Recurrence of focal glomeruloscierosis despite cyclosporin treatment after renal transplantation SIR,-Professor Alain Meyrier and colleagues ( 22March, p 789) repprted the remission of the idiopathic nephrotic syndrome after cyclosporin therapy.While the remission was total in the three patients with minimal change nephropathy, it was only partial in the three others with focal glomerulosclerosis.The authors considered the
Frequency and severity of ileal adenomas in familial adenomatous polyposis after colectomy
Authors: D. Moussata, S. Nancey, M. Lapalus, B. Prost, A. Chavaillon, G. Bernard, T. Ponchon, J. Saurin
Journal: Endoscopy (2007)

See also: Commentaire de travail de D. Moussata et al., pp. 120Endoscopy 2008; 40(02): 234-234DOI: 10.1055/s-0032-1306808
Case-by-Case Assessment of Recoverable Materials for Overseas Donation From 1318 Surgical Procedures
Authors: William H. Rosenblatt
Journal: JAMA (1993)

<h3>Objective.</h3> —To provide a mechanism for addressing the need for consistency and projection in overseas donation of surgical supplies, we conducted a case-by-case inventory of unused materials recovered from all surgical procedures in our facility over a 2.5-month period. <h3>Design.</h3> —Unused surgical supplies were recovered in coded bags from individual cases and inventoried. <h3>Setting.</h3> —Inpatient operating rooms at Yale—New Haven Hospital. <h3>Main Outcome Measure.</h3> —The weight and dollar value of recovered materials were tallied for each case type; these were then extrapolated according to the frequency with which each procedure is performed in the United States to provide an estimate of the impact of a nationwide recovery program. <h3>Results.</h3> —The value of supplies recovered ranged from $1 (bone marrow transplant) to greater than $40 (liver and vulva/perineum procedures). By extrapolation to case-specific data from the National Hospital Discharge Survey (1990), we estimate that a nationwide recovery program could yield more than $193 million in charitable material and reduce operating room waste by more than 1.7 million kilograms (1948 tons). <h3>Conclusions.</h3> —Consistency and organization would contribute greatly to efforts to alleviate existing medical supply needs in the developing world. This case-by-case assessment should enable participating centers to project more effectively the outcome of such collections and allow the coordination of efforts. Though unlikely to be adopted by all operating theaters in the United States, the potential charitable contributions from a nationwide recovery program are significant. (<i>JAMA</i>. 1993;269:2647-2649)
A study by means of a new assay of the relationship between an outbreak of erythema infectiosum and non-immune hydrops fetalis caused by human parvovirus B19
Authors: Nobuo Yaegashi, Kunihiro Okamura, Akira Tsunoda, Masataka Nakamura, Kazuo Sugamura, Akira Yajima
Journal: Journal of Infection (1995)
The Forces Needed to Evoke Sounds from Cardiac Tissues, and the Attenuation of Heart Sounds
Authors: WILLIAM DOCK
Journal: Circulation (1959)

There has been no study of the efficiency of any sound-producing system. Here there is a description of a device that records the force of each pull applied to a valve segment or strip of myocardium while the sound evoked is recorded. The relation of force to sound intensity, and the attenuation of sounds in air, blood, and ventricular and chest walls provide some quantitative data on a neglected phase of cardiac physiology.
Cuba shows health gains despite embargo
Authors: C. Chelala
Journal: BMJ (1998)

Recent official statistics from Cuba's ministry of public health show significant gains in some important health status indicators despite the trade embargo imposed by the United States.

Infant mortality in Cuba by the end of 1997 had reached an all time low of 7.2 per 1000 live births, compared with 7.9 in 1996. Cuba now ranks among the 25 countries in the world with the lowest infant mortality.

A reduction has also been observed in maternal mortality, which fell from 23.5 per 100000 live births in 1996 to 22.0 …
Sex hormone-binding globulin and saliva testosterone levels in men with androgenetic alopecia
Authors: R. CIPRIANI, G. RUZZA, C. FORESTA, C. VELLER FORNASA, A. PESERICO
Journal: British Journal of Dermatology (1983)

Sex hormone binding globulin (SHBG), plasma testosterone and saliva testosterone were measured in sixty-four men with androgenetic alopecia and in forty males within the same age range without alopecia. There was a significant reduction in SHBG levels in bald men, compared with controls. Plasma testosterone levels were not raised in bald men, but their salivary testosterone levels were significantly higher than in controls.
Rubella and the Congenital Rubella Syndrome.
Authors: Saul Krugman
Journal: Annals of Internal Medicine (1965)

s1 November 1965Rubella and the Congenital Rubella Syndrome.Saul Krugman, M.D.Saul Krugman, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-63-5-914_3 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe epidemic of rubella in the United States in 1964 was followed by the birth of many thousands of infants with congenital rubella syndrome. This syndrome was characterized by one or more of the following manifestations: (1) intrauterine growth retardation, (2) thrombocytopenic purpura, (3) eye lesions (cataract or glaucoma), (4) congenital heart disease (patent ductus arteriosus or septal defects or both), (5) brain lesions (microcephaly, hydrocephalus or meningo-encephalitis), (6) hepatosplenomegaly, (7) hepatitis, and (8) bone lesions.Rubella virus isolatin studies by many investigators have revealed the following: (1) presence of virus in fetal tissues for weeks and months after maternal... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, New York PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 November 1965Volume 63, Issue 5Page: 914-915KeywordsGlaucomaHepatitisHepatosplenomegalyHydrocephalusInfantsIntrauterine growth restrictionLesionsMicrocephalyPatent ductus arteriosusRubella Issue Published: 1 November 1965 PDF downloadLoading ...
Preserved in Wax.
Authors: F. B. Marshall
Journal: JAMA (1903)

ABSTRACT Muskegon, Mich., May 22, 1903.To the Editor: —The following case illustrates the remarkable preservative properties of cerumen: J. W. S., age 63; white; Civil War veteran. A beetle of the species Tenebrio molitor entered right ear one evening in August, 1861, while patient was in Camp Good Hope, near Navy Yards, Washington, D. C. Patient immediately applied to regimental surgeon, who, failing in efforts to remove insect, applied olive oil to ear and instructed patient to return to tent and lie on right side, and suggested that the bug would probably be found on blanket in the morning. Pain in ear kept patient awake until nearly morning and when awakened ear felt much better, and patient forgot to look on blanket for insect, which he supposed had escaped from the ear. Since insect entered ear, patient has been able to hear but faintly with right ear.Patient applied to
The Acute Surgical Abdomen in Children
Authors: Thomas M. Holder, Lucian L. Leape
Journal: New England Journal of Medicine (1967)

A FEW of the more common surgical conditions occurring in childhood that require prompt therapy will be reviewed in the light of current knowledge. For the purpose of this discussion, the acute surgical abdomen is defined as those conditions requiring prompt abdominal operation. These may be conveniently grouped into four major classes: diseases in which the predominating complaint is abdominal pain; the various forms of intestinal obstruction; gastrointestinal bleeding; and trauma.Abdominal PainLess than 10 per cent of children coming to medical attention because of abdominal pain will require an operation. Within this group, however, are almost all those . . .
Assessment of the efficacy of cryosurgery in the treatment of granuloma faciale
Authors: A. Panagiotopoulos, V. Anyfantakis, E. Rallis, V. Chasapi, P. Stavropoulos, C. Boubouka, A. Katsambas
Journal: British Journal of Dermatology (2006)

Journal Article Assessment of the efficacy of cryosurgery in the treatment of granuloma faciale Get access A. Panagiotopoulos, A. Panagiotopoulos Department of Cryosurgery, ‘A. Sygros’ Hospital, 5I. Dragoumi Str, 16121, Athens, Greece *Department of Dermatology, General Military Hospital, Athens, Greece Search for other works by this author on: Oxford Academic Google Scholar V. Anyfantakis, V. Anyfantakis Department of Cryosurgery, ‘A. Sygros’ Hospital, 5I. Dragoumi Str, 16121, Athens, Greece *Department of Dermatology, General Military Hospital, Athens, Greece Vasileios Anyfantakis MD. E‐mail: anyfantava@yahoo.gr Search for other works by this author on: Oxford Academic Google Scholar E. Rallis, E. Rallis Department of Cryosurgery, ‘A. Sygros’ Hospital, 5I. Dragoumi Str, 16121, Athens, Greece *Department of Dermatology, General Military Hospital, Athens, Greece Search for other works by this author on: Oxford Academic Google Scholar V. Chasapi, V. Chasapi Department of Cryosurgery, ‘A. Sygros’ Hospital, 5I. Dragoumi Str, 16121, Athens, Greece *Department of Dermatology, General Military Hospital, Athens, Greece Search for other works by this author on: Oxford Academic Google Scholar P. Stavropoulos, P. Stavropoulos Department of Cryosurgery, ‘A. Sygros’ Hospital, 5I. Dragoumi Str, 16121, Athens, Greece *Department of Dermatology, General Military Hospital, Athens, Greece Search for other works by this author on: Oxford Academic Google Scholar C. Boubouka, C. Boubouka Department of Cryosurgery, ‘A. Sygros’ Hospital, 5I. Dragoumi Str, 16121, Athens, Greece *Department of Dermatology, General Military Hospital, Athens, Greece Search for other works by this author on: Oxford Academic Google Scholar A. Katsambas A. Katsambas Department of Cryosurgery, ‘A. Sygros’ Hospital, 5I. Dragoumi Str, 16121, Athens, Greece *Department of Dermatology, General Military Hospital, Athens, Greece Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 154, Issue 2, 1 February 2006, Pages 357–360, https://doi.org/10.1111/j.1365-2133.2005.07093.x Published: 01 February 2006 Article history Accepted: 04 April 2005 Published: 01 February 2006
Children whose parents attempted suicide are at raised risk of similar behaviour, study finds
Authors: I. Torjesen
Journal: BMJ (2015)

The child of a parent who has attempted suicide is almost five times as likely to attempt suicide as the child of a parent with no history of suicidal behaviour, a study published in JAMA Psychiatry has found.

US researchers followed up 701 children (ages 10 to 50) of 334 parents with mood disorders for a mean of 5.6 years, where …
Quantitative Electron Microscopy
Authors: David W. Hamilton
Journal: JAMA (1966)

The intent of the editors of this book (originally published as a supplement to volume 14 of Laboratory Investigation ) is to bring together in one volume papers on topics from all aspects of electron microscopy that previously were available only from widely scattered sources. Papers by various authors are arranged in a more or less logical sequence starting with image formation and progressing to the final electron micrograph and its quantitative evaluation.  The range of topics dealt with is wide, encompassing both biological and physical problems in electron microscopy. Many of the papers dealing with the physical aspects of electron microscopy are theoretical and, thus, of relatively little value to biologists, whereas others give practical information on such things as determination of magnification, reduction of contamination and the like that will be generally useful. However, the problems (such as fixation, dehydration, embedding and sectioning of tissues) that face the biologist
Dual-energy CT for the diagnosis of gout: an accuracy and diagnostic yield study
Authors: Tim Bongartz, Katrina N Glazebrook, Steven J Kavros, Naveen S Murthy, Stephen P Merry, Walter B Franz, Clement J Michet, Barath M Akkara Veetil, John M Davis, Thomas G Mason, Kenneth J Warrington, Steven R Ytterberg, Eric L Matteson, Cynthia S Crowson, Shuai Leng, Cynthia H McCollough
Journal: Annals of the Rheumatic Diseases (2014)

To assess the accuracy of dual-energy CT (DECT) for diagnosing gout, and to explore whether it can have any impact on clinical decision making beyond the established diagnostic approach using polarising microscopy of synovial fluid (diagnostic yield).Diagnostic single-centre study of 40 patients with active gout, and 41 individuals with other types of joint disease. Sensitivity and specificity of DECT for diagnosing gout was calculated against a combined reference standard (polarising and electron microscopy of synovial fluid). To explore the diagnostic yield of DECT scanning, a third cohort was assembled consisting of patients with inflammatory arthritis and risk factors for gout who had negative synovial fluid polarising microscopy results. Among these patients, the proportion of subjects with DECT findings indicating a diagnosis of gout was assessed.The sensitivity and specificity of DECT for diagnosing gout was 0.90 (95% CI 0.76 to 0.97) and 0.83 (95% CI 0.68 to 0.93), respectively. All false negative patients were observed among patients with acute, recent-onset gout. All false positive patients had advanced knee osteoarthritis. DECT in the diagnostic yield cohort revealed evidence of uric acid deposition in 14 out of 30 patients (46.7%).DECT provides good diagnostic accuracy for detection of monosodium urate (MSU) deposits in patients with gout. However, sensitivity is lower in patients with recent-onset disease. DECT has a significant impact on clinical decision making when gout is suspected, but polarising microscopy of synovial fluid fails to demonstrate the presence of MSU crystals.
THE INDUCTION OF GRAFT VERSUS HOST DISEASE IN MICE TREATED WITH CYCLOPHOSPHAMIDE
Authors: Albert H. Owens, George W. Santos
Journal: The Journal of Experimental Medicine (1968)

In these studies adult mice treated with cyclophosphamide and foreign immunologically competent cells developed a graft versus host disease which outwardly resembled that encountered in other experimental systems. Progressively larger doses of cyclophosphamide produced an increasingly severe disease whereas comparable doses of mechlorethamine were ineffective. Increasingly larger cell inocula from parental, allogeneic, and xenogeneic donors resulted in a correspondingly more severe disease. Nucleated cells obtained from the peripheral blood were found to be the most potent inducers of this syndrome, while cells from the spleen, bone marrow, and thymus displayed lesser degrees of reactivity in that order. No such graft versus host disease occurred in mice given saline, lysed, or heat-killed cells in place of viable foreign cells. Neither did the disorder develop when comparable inocula of isogeneic cells were used.
What is freedom–and does wealth cause it?
Authors: Ravi Iyer, Matt Motyl, Jesse Graham
Journal: Behavioral and Brain Sciences (2013)

Abstract The target article's climato-economic theory will benefit by allowing for bidirectional effects and the heterogeneity of types of freedom, in order to more fully capture the coevolution of societal wealth and freedom. We also suggest alternative methods of testing climato-economic theory, such as longitudinal analyses of these countries' histories and micro-level experiments of each of the theory's hypotheses.
Concept of Benign Myalgic Encephalomyelitis
Authors: C. P. McEvedy, A. W. Beard
Journal: BMJ (1970)

The reports of the 15 recorded outbreaks of benign myalgic encephalomyelitis have been reviewed and in one instance the original clinical data studied. We believe that a lot of these epidemics were psychosocial phenomena caused by one of two mechanisms, either mass hysteria on the part of the patients or altered medical perception of the community. We suggest that the name "myalgia nervosa" should be used for any future cases of functional disorder which present the same clinical picture.
Landmark article Sept 8, 1923. An ovarian hormone. Preliminary report on its localization, extraction and partial purification, and action in test animals. By Edgar Allen and Edward A. Doisy
Authors: E. Allen
Journal: JAMA (1983)

The fact that double ovariectomy abolishes the cyclic changes which normally occur in the genital tract of female mammals demonstrates that these changes are due to some influence from the ovaries. That this influence is hormonal in nature is indicated by the maintenance of cyclic changes by autotransplantation of the ovaries to other sites in the body.<sup>1</sup>Many attempts have been made to localize the seat of production of an internal secretion in definite ovarian structures. The follicles, the corpora lutea<sup>2</sup>developing in them after ovulation, and the interstitial tissue<sup>3</sup>have all been cited as possible sources, and many different ovarian preparations have been used clinically in the belief that therapeutic effects were being secured from accompanying hormones. But there appears to be no conclusive evidence of either a definite localization of the hypothetic hormone or of the specific effect claimed for the commercial ovarian extracts in
Long-Term Right Ventricular Volume Overload Increases Myocardial Fluorodeoxyglucose Uptake in the Interventricular Septum in Patients With Atrial Septal Defect
Authors: Hiroki Otani, Yutaka Kagaya, Yuriko Yamane, Masanobu Chida, Kenta Ito, Shigeto Namiuchi, Nobuyuki Shiba, Yoshito Koseki, Mototsugu Ninomiya, Jun Ikeda, Haruo Saito, Shin Maruoka, Takehiko Fujiwara, Tatsuo Ido, Nobumasa Ishide, Kunio Shirato
Journal: Circulation (2000)

Background —Several studies have shown that long-term right ventricular (RV) overload in animal models alters myocardial energy substrate metabolism. However, whether long-term RV volume overload alters this metabolism in the human is unclear. Methods and Results —We performed positron emission tomography with [ 18 F]fluorodeoxyglucose (FDG) and single-photon emission tomography (SPECT) with [ 201 Tl]TlCl (Tl) and [ 123 I]15-( p -iodophenyl)-3- R,S -methylpentadecanoic acid (BMIPP) in 11 patients with atrial septal defect (ASD) and 11 control subjects. In the FDG study, we calculated myocardial metabolic rate of glucose (MMR) in interventricular septum (IVS) and left ventricular (LV) free wall. MMR was significantly increased in IVS compared with LV free wall in the ASD patients (420±35 versus 333±32 mol · kg −1 · min −1 ; P &lt;0.05) but not in the control group (347±27 versus 357±25 mol · kg −1 · min −1 ). In both ASD and control groups, SPECT count was not significantly different between IVS and LV free wall in Tl (ASD, 160±11 versus 177±12; control, 141±12 versus 157±14 counts per 15 minutes) and BMIPP studies (ASD, 203±14 versus 212±18; control, 162±16 versus 176±16 counts per 15 minutes). MMR in the IVS/LV free wall ratio in the ASD group significantly correlated with indices related to RV volume overload. Conclusions —Given the assumption that long-term RV volume overload did not affect the lumped constant, the present study suggests that, unlike myocardial perfusion or fatty acid analogue uptake, myocardial glucose utilization in IVS relative to LV free wall is increased in relation to long-term RV volume overload in patients with ASD.