Cortisone Responsive Hypercalcemia in Proved Hyperparathyroidism
Authors: GRANT GWINUP
Journal: Annals of Internal Medicine (1961)

Case Reports1 December 1961Cortisone Responsive Hypercalcemia in Proved HyperparathyroidismGRANT GWINUP, M.D., BETTYE SAYLE, M.D.GRANT GWINUP, M.D.Search for more papers by this author, BETTYE SAYLE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-55-6-1001 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThere is no available assay for parathyroid hormone in the serum. In the absence of such a specific determination, it is necessary to rely on nonspecific procedures to differentiate hyperparathyroidism from the other hypercalcemic states. The effect of the administration of corticosteroids on the elevated serum calcium levels is one such procedure currently applied in difficult problems of differential diagnosis. It is the purpose of this report to present an exception to previous experience with this procedure in a patient with proved hyperparathyroidism.The hypercalcemia of sarcoidosis has consistently responded to steroid administration (1-4). In one case of proved sarcoidosis...References1. SCHULMANSCHOENRICHHARVEY LEEHAM: Effect of adrenocorticotrophic hormone (ACTH) and cortisone on sarcoidosis. Bull. Johns Hopkins Hosp. 91: 371, 1952. MedlineGoogle Scholar2. GOETZ AA: Effect of cortisone on hypercalcemia in sarcoidosis; relief of gastrointestinal, dermatological and renal symptoms with steroid therapy. J. A. M. A. 174: 380, 1960. CrossrefMedlineGoogle Scholar3. ELLMANPARFITT TAM: The resemblance between sarcoidosis with hypercalcemia and hyperparathyroidism. Brit. Med. J. 5192: 108, 1960. CrossrefGoogle Scholar4. THOMASCONNORMORGAN WCTBHG: Diagnostic considerations in hypercalcemia: with discussion of various means by which such a state may develop. New Engl. J. Med. 260: 591, 1959. CrossrefMedlineGoogle Scholar5. BURRFARRELLHILLS JMJJAG: Sarcoidosis and hyperparathyroidism with hypercalcemia: special usefulness of the cortisone test. New Engl. J. Med. 261: 1271, 1959. CrossrefMedlineGoogle Scholar6. CONNORHOPKINSTHOMASCARREYHOWARD TBTRWCRAJE: Use of cortisone and ACTH in hypercalcemic states. J. Clin. Endocr. 16: 945, 1956. Google Scholar7. MYERS WP: Hypercalcemia in neoplastic disease. Arch. Surg. 80: 308, 1960. CrossrefMedlineGoogle Scholar8. LUCAS TF: Acute hypercalcemia from carcinomatosis without bone metastasis. Brit. Med. J. 5182: 1330, 1960. CrossrefGoogle Scholar9. KABAKOWMINESKING BMDFJ: Hypercalcemia in Hodgkins' disease. New Engl. J. Med. 256: 59, 1957. CrossrefMedlineGoogle Scholar10. WILLIAMSMOSER MBJH: Colorimetric determination of calcium with ammonium purpurate. Anal. Chem. 25: 1414, 1953. CrossrefGoogle Scholar11. HARRISON HE: Factors influencing calcium absorption. Fed. Proc. 18: 2205, 1959. Google Scholar12. DETONINORDIO ES: The relationship between calcium-phosphate metabolism, the Kreb's cycle, and steroid metabolism. Arch. Dis. Child. 34: 371, 1959. CrossrefMedlineGoogle Scholar13. LAAKE H: The action of cortical steroids on the renal reabsorption of calcium. Acta Endocr. 34: 60, 1960. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: GRANT GWINUP, M.D.; BETTYE SAYLE, M.D.Affiliations: Galveston, TexasFrom the Department of Internal Medicine, The University of Texas—Medical Branch, Galveston, Texas.Requests for reprints should be addressed to Grant Gwinup, M.D., Department of Internal Medicine, Division of Endocrinology, Ohio State University Hospital, Columbus, Ohio. 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DONATELLI, M.D.Hypercalcaemia in Renal CarcinomaAnnotationsCase 63-1963The syndrome of hypoparathyroidism and adrenocortical insufficiency, a possible sequel of hepatitisParathyroid adenoma in a childCoexisting Hyperthyroidism and HyperparathyroidismElectrolyte Complications of Drug TherapySuppression of the Hypercalcemia of Thyrotoxicosis by Corticosteroids 1 December 1961Volume 55, Issue 6Page: 1001-1004KeywordsAdenomasCalciumHypercalcemiaHyperparathyroidismIntoxicationLymphomaMultiple myelomaParathyroid hormoneSarcoidosis ePublished: 1 December 2008 Issue Published: 1 December 1961 PDF downloadLoading ...