Fibroblastic Growth Factor and Infarct Size
Authors: Wayne P. Franco, Arthur W. Bracey, Kenneth L. Franco, Charles A. Hufnagel, Dietmar H. Glogar, Robert A. Kloner
Journal: Annals of Internal Medicine (1980)

Letters and Corrections1 October 1980Fibroblastic Growth Factor and Infarct SizeWAYNE P. FRANCO, M.D., ARTHUR W. BRACEY, M.D., KENNETH L. FRANCO, M.D., CHARLES A. HUFNAGEL, M.D., DIETMAR H. GLOGAR, M.D., ROBERT A. KLONER, M.D., PH.D.WAYNE P. FRANCO, M.D.Search for more papers by this author, ARTHUR W. BRACEY, M.D.Search for more papers by this author, KENNETH L. FRANCO, M.D.Search for more papers by this author, CHARLES A. HUFNAGEL, M.D.Search for more papers by this author, DIETMAR H. GLOGAR, M.D.Search for more papers by this author, ROBERT A. KLONER, M.D., PH.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-93-4-637 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Based on an Interdepartmental UCLA Conference, Golde and associates (1) have presented a superb review of the current status of in-vitro research into humoral growth factors. Yet little account is given to the potential clinical importance of growth factors in the future treatment of diseases that involve abnormal cell proliferation, as is the case in cancer or diseases related to atherosclerosis.Recently in-vivo angiogenesis by growth factors was shown by Gospodarowicz and associates (2) using the avascular rabbit cornea as a model. Fibroblastic growth factor or epidermal growth factor incorporated into a slow-release form of Elwax 40...References1. GOLDE D, HERSCHMAN H, LUSIS A, and GROOPMAN J. Growth factors. Ann Intern Med. 1980;92:650-62. LinkGoogle Scholar2. GOSPODAROWICZ D, BIALECKI H, and THAKRAL T. The angiogenic activity of the fibroblast and epidermal growth factor. Exp Eye Res. 1979;28:501-14. CrossrefMedlineGoogle Scholar3. FOLKMAN J. Tumor angiogenesis: a possible control point in tumor growth. Ann Intern Med. 1975;82:96-100. LinkGoogle Scholar4. SVET-MOLDAVSKY G and CHIMISHKYAN K. Tumour angiogenesis factor for revascularisation in ischaemia and myocardial infarction. Lancet. 1977;1:913. Letter. CrossrefMedlineGoogle Scholar5. GOSPODAROWICZ D. Purification of fibroblast growth factor from bovine pituitary. J Biol Chem. 1975;250:2515-20. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: WAYNE P. FRANCO, M.D.; ARTHUR W. BRACEY, M.D.; KENNETH L. FRANCO, M.D.; CHARLES A. HUFNAGEL, M.D.; DIETMAR H. GLOGAR, M.D.; ROBERT A. KLONER, M.D., PH.D. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDelivery of drugs, growth factors, genes and stem cells via intrapericardial, epicardial and intramyocardial routes for sustained local targeted therapy of myocardial diseaseRelationships of growth factors, proinflammatory cytokines, and anti-inflammatory cytokines with long-term clinical results of autologous bone marrow mononuclear cell transplantation in STEMIThe Combined Administration of Multiple Soluble Factors in the Repair of Chronically Infarcted Rat MyocardiumImproving regenerating potential of the heart after myocardial infarction: Factor-based approachPropriétés in vitro de quelques facteurs de croissance et effets in vivo 1 October 1980Volume 93, Issue 4Page: 637-638KeywordsAngiogenesisAtherosclerosisCancer treatmentCell proliferationCorneaEpidermal growth factorForecastingGrowth factorsRabbits ePublished: 1 December 2008 Issue Published: 1 October 1980 PDF downloadLoading ...