Recent Advances in the Rheumatic Diseases
Authors: EPHRAIM P. ENGLEMAN
Journal: Annals of Internal Medicine (1967)

Review1 January 1967Recent Advances in the Rheumatic DiseasesEPHRAIM P. ENGLEMAN, M.D., F.A.C.P., MARTIN A. SHEARN, M.D., F.A.C.P.EPHRAIM P. ENGLEMAN, M.D., F.A.C.P.Search for more papers by this author, MARTIN A. SHEARN, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-66-1-199 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptA review of American and English literature on rheumatism and arthritis was last published in this journal in 1964. An excellent sequel to that review has appeared elsewhere (2). It is not our purpose to duplicate such an exhaustive discussion and critique of the literature but rather to present the highlights of recent advances in clinical rheumatology, without attempting to be all-inclusive.RHEUMATOID ARTHRITISETIOLOGYA number of factors, either alone or in combination, have been implicated in the causation of rheumatoid arthritis (RA). Because both the disease and positive serologic reactions appeared to occur more frequently in family members...References1. SMYTHBLACKCHRISTIANCLAYTONHILLHOLLANDERMIKKELSENMONTGOMERYPEARSONSMYTHEWARDWEINBERGER CJRLCMLDFJLWMMMCMHALEHJ: Rheumatism and arthritis: review of American and English literature of recent years. Ann. Intern. Med. 61: (suppl. 6): 1, 1964. LinkGoogle Scholar2. CHRISTIANBUTLERDECKERHAMERMANKRANEMIKKELSENPEARSONSMYTHTARANTATOMASIWARDWEINBERGER CLVPJLDSMWMCMHAATBLEHJ (editors): Rheumatism and arthritis: review of American and English literature for the years 1963 and 1964. Arthritis Rheum. 9: 93, 1966. MedlineGoogle Scholar3. BURCHO'BRIENBUNIM TAWMJJ: Family and genetic studies of rheumatoid arthritis and rheumatoid factor in Blackfeet Indians. Amer. J. Public Health 54: 1184, 1964. CrossrefGoogle Scholar4. DAVISGOUGH JSWW: A protective role for rheumatoid factor (abstract). Clin. Res. 14: 331, 1966. Google Scholar5. PATERSONHARWIN PYSM: Suppression of allergic encephalomyelitis in rats by means of antibrain serum. J. Exp. Med. 117: 755, 1963. CrossrefMedlineGoogle Scholar6. SHEARNEPSTEINENGLEMANTAYLOR MAWVEPWF: Relationship of serum proteins and rheumatoid factor to serum viscosity in rheumatic diseases. J. Lab. Clin. Med. 61: 677, 1963. MedlineGoogle Scholar7. BAUMSTASTNYZIFF JPM: Effects of the rheumatoid factor and antigen-antibody complexes on the vessels of the rat mesentery. J. Immun. 93: 985, 1964. MedlineGoogle Scholar8. MOOSSOLOMON RHGF: Psychologic comparisons between women with rheumatoid arthritis and their nonarthritic sisters. II. Content analysis of interviews. Psychosom. Med. 27: 150, 1965. CrossrefMedlineGoogle Scholar9. BARTHOLOMEW LE: Isolation and characterization of mycoplasmas (PPLO) from patients with rheumatoid arthritis, systemic lupus erythematosus and Reiter's syndrome. Arthritis Rheum. 8: 376, 1965. CrossrefMedlineGoogle Scholar10. BYWATERSSCOTT EGJT: The natural history of vascular lesions in rheumatoid arthritis. J. Chronic Dis. 16: 905, 1963. CrossrefMedlineGoogle Scholar11. MESARABRODYOBERMAN BWGLHA: "Pseudorheumatoid" subcutaneous nodules. Amer. J. Clin. Path. 45: 684, 1966. CrossrefMedlineGoogle Scholar12. ZVAIFLERWEINTRAUB NJAM: Aortitis and aortic insufficiency in the chronic rheumatic disorders—a reappraisal. Arthritis Rheum. 6: 241, 1963. CrossrefMedlineGoogle Scholar13. SOBINHAGSTROM LHJW: Lesions of cardiac conduction tissue in rheumatoid aortitis. JAMA 180: 1, 1962. CrossrefMedlineGoogle Scholar14. LONDONTOMASI MGTB: The lung in rheumatoid disease. Geriatrics 20: 61, 1965. MedlineGoogle Scholar15. NOONANTAYLORENGLEMAN CDFBEP: Nodular rheumatoid disease of the lung with cavitation. Arthritis Rheum. 6: 232, 1963. CrossrefMedlineGoogle Scholar16. HUMEDAGGFRASERGOLDBERG RJHTNA: Anaemia of Felty's syndrome. Ann. Rheum. Dis. 23: 267, 1964. CrossrefMedlineGoogle Scholar17. MONGANJACOX ESRF: Erythrocyte survival in rheumatoid arthritis. Arthritis Rheum. 7: 481, 1964. CrossrefMedlineGoogle Scholar18. CHRISTIAN CL: The rheumatoid factors. J. Chronic Dis. 16: 875, 1963. CrossrefMedlineGoogle Scholar19. SHARPCALKINSCOHENSCHUBARTCALABRO JTEASAFJJ: Observations on the clinical, chemical, and serological manifestations of rheumatoid arthritis, based on the course of 154 cases. Medicine (Balt.) 43: 41, 1964. CrossrefMedlineGoogle Scholar20. CONDEMIBARNETTATWATERJACOXMONGANVAUGHAN JJEVECRFESJH: The significance of antinuclear factors in rheumatoid arthritis. Arthritis Rheum. 8: 1080, 1965. CrossrefMedlineGoogle Scholar21. ZUCKER-FRANKLIN D: The phagosomes in rheumatoid synovial fluid leukocytes: a light, fluorescence, and electron microscope study. Arthritis Rheum. 9: 24, 1966. CrossrefMedlineGoogle Scholar22. HOLLANDERMCCARTYASTORGACASTRO-MURILLO JLDJGE: Studies on the pathogenesis of rheumatoid joint inflammation. I. The "R. A. cell" and a working hypothesis. Ann. Intern. Med. 62: 271, 1965. LinkGoogle Scholar23. PIERSONHOLTWATSONKEATING RNPRRMRP: Aspirin and gastrointestinal bleeding. Chromate blood loss studies. Amer. J. Med. 31: 259, 1961. CrossrefMedlineGoogle Scholar24. Editorial: Analgesic nephrotoxicity: a pharmacological analysis. Amer. J. Med. 36: 167, 1964. CrossrefMedlineGoogle Scholar25. BRUNOLSENRAASCHOUSØRENSEN CSFAW: Renal biopsy in rheumatoid arthritis. Nephron 2: 65, 1965. CrossrefMedlineGoogle Scholar26. : Gold therapy in rheumatoid arthritis: final report of a multicentre controlled trial. Ann. Rheum. Dis. 20: 315, 1961. CrossrefMedlineGoogle Scholar27. PERSELLINZIFF RHM: The effect of gold salt on lysosomal enzymes of the peritoneal macrophage. Arthritis Rheum. 9: 57, 1966. CrossrefMedlineGoogle Scholar28. LEEDUSHKINEYRINGENGLEMANHOPPER JCMEJEPJ: Renal lesions associated with gold therapy; light and electron microscopic studies. Arthritis Rheum. 8: 1, 1965. CrossrefMedlineGoogle Scholar29. BRUNOLSENRAASCHOUSØRENSEN CSFAW: The localization of gold in the human kidney following chrysotherapy: a biopsy study. Nephron 1: 265, 1964. CrossrefMedlineGoogle Scholar30. EYRINGENGLEMAN EJEP: Interaction of gold and penicillamine. Arthritis Rheum. 6: 216, 1963. CrossrefGoogle Scholar31. HURVITZHIRSCHHORN DK: Suppression of in vitro lymphocyte responses by chloroquine. New Eng. J. Med. 273: 23, 1965. CrossrefMedlineGoogle Scholar32. CRANE CV: Posterior subcapsular cataracts. Report of a case at the age of forty years in a man under prolonged steroid therapy for Marie-Strümpell disease. Amer. J. Ophthal. 56: 307, 1963. CrossrefMedlineGoogle Scholar33. SMITH B: Histological and histochemical changes in the muscles of rabbits given the corticosteroid triamcinolone. Neurology (Minneap.) 14: 857, 1964. CrossrefMedlineGoogle Scholar34. JONESENGLEMANNAJARIAN JPEPJS: Systemic fat embolism after renal homotransplantation and treatment with corticosteroids. New Eng. J. Med. 273: 1453, 1965. CrossrefMedlineGoogle Scholar35. JONESSAKOVICH JPL: Fat embolism of bone. A roentgenographic and histological investigation with use of intra-arterial lipiodol, in rabbits. J. Bone Joint Surg. [Amer.] 48: 149, 1966. CrossrefGoogle Scholar36. GRANTFORSHAMDI RAIMONDO SDPHVC: Suppression of 17-hydroxycorticosteroids in plasma and urine by single and divided doses of triamcinolone. New Eng. J. Med. 273: 1115, 1965. CrossrefMedlineGoogle Scholar37. RAGAN C: Personal communication. Google Scholar38. LARSONMCEWEN CBC: Conference on criteria for, and evaluation of, orthopedic measures in the management of deformities of rheumatoid arthritis. Arthritis Rheum. 7: 550, 1964. Google Scholar39. LANGETRESERSAGELTYWASSERMAN KGLAE: Routine immunohistology in renal diseases. Ann. Intern. Med. 64: 25, 1966. LinkGoogle Scholar40. LEONHARDT T: Family studies in systemic lupus erythematosus. Acta Med. Scand. 176 (suppl. 416): 1, 1964. MedlineGoogle Scholar41. HELYERHOWIE BJJB: Spontaneous autoimmune disease in NZB/BL mice. Brit. J. Haemat. 9: 119 1963. CrossrefMedlineGoogle Scholar42. CHANNINGKASUGAHOROWITZDUBOISDEMOPOULOS AATREELHB: An ultrastructural study of spontaneous lupus nephritis in the NZB/BL-NZW mouse. Amer. J. Path. 47: 677, 1965. MedlineGoogle Scholar43. DIXONFELDMANVAZQUEZ FJJDJJ: Experimental glomerulonephritis. The pathogenesis of a laboratory model resembling the spectrum of human glomerulonephritis. J. Exp. Med. 113: 899, 1961. CrossrefMedlineGoogle Scholar44. TANKUNKEL EMHG: An immunofluorescent study of the skin lesions in systemic lupus erythematosus. Arthritis Rheum. 9: 37, 1966. CrossrefMedlineGoogle Scholar45. ALARCÓN-SEGOVIAWORTHINGTONWARDWAKIN DJWLEKG: Lupus diathesis and the hydralazine syndrome. New Eng. J. Med. 272: 462, 1965. CrossrefMedlineGoogle Scholar46. ROTHFIELDMARCHMIESCHERMCEWEN NCHPC: Chronic discoid lupus erythematosus: a study of 65 patients and 65 controls. New Eng. J. Med. 269: 1155, 1963. CrossrefMedlineGoogle Scholar47. NOONANODONEENGLEMANSPLITTER CDDTEPSD: Roentgenographic manifestations of joint disease in systemic lupus erythematosus. Radiology 80: 837, 1963. CrossrefMedlineGoogle Scholar48. HUANGHENNIGARLYONS CTGRHA: Pulmonary dysfunction in systemic lupus erythematosus. New Eng. J. Med. 272: 288, 1965. CrossrefMedlineGoogle Scholar49. SHEARN MA: Normocholesterolemic nephrotic syndrome of systemic lupus erythematosus. Amer. J. Med. 36: 250, 1964. CrossrefMedlineGoogle Scholar50. STEVENSHOOKMANSIEGELESTERLYSHULMANHENDRIX MBPCIJRLETR: Aperistalsis of the esophagus in patients with connective-tissue disorders and Raynaud's phenomenon. New Eng. J. Med. 270: 1218, 1964. CrossrefMedlineGoogle Scholar51. KURLANDERKIRSNER DJJB: The association of chronic "nonspecific" inflammatory bowel disease with lupus erythematosus. Ann. Intern. Med. 60: 799, 1964. LinkGoogle Scholar52. HUTCHINSHARVEY GMAM: The thymus in systemic lupus erythematosus. Bull. Hopkins Hosp. 115: 355, 1964. MedlineGoogle Scholar53. POLLAKPIRANISCHWARTZ VECLFD: The natural history of the renal manifestations of systemic lupus erythematosus. J. Lab. Clin. Med. 63: 537, 1964. MedlineGoogle Scholar54. ROTHFIELDMCCLUSKEYBALDWIN NFRTDS: Renal disease in systemic lupus erythematosus. New Eng. J. Med. 269: 537, 1963. CrossrefMedlineGoogle Scholar55. SHEARN MA: Mercaptopurine in the treatment of steroid-resistant nephrotic syndrome. New Eng. J. Med. 273: 943, 1965. CrossrefMedlineGoogle Scholar56. ALARCÓN-SEGOVIABROWN DAL: Classification and etiologic aspects of necrotizing angiitides: an analytic approach to a confused subject with a critical review of the evidence for hypersensitivity in polyarteritis nodosa. Mayo Clin. Proc. 39: 205, 1964. MedlineGoogle Scholar57. BLEEHENLOVELACECOTTON SSRERE: Mononeuritis multiplex in polyarteritis nodosa. Quart. J. Med. 32: 193, 1963. MedlineGoogle Scholar58. WINKELMANNDITTO RKWB: Cutaneous and visceral syndromes of necrotizing or "allergic" angiitis: a study of 38 cases. Medicine (Balt.) 43: 59, 1964. CrossrefMedlineGoogle Scholar59. DRACHMAN DA: Neurological complications of Wegener's granulomatosis. Arch. Neurol. (Chicago) 8: 145, 1963. CrossrefGoogle Scholar60. MCILVANIE SK: Wegener's granulomatosis: successful treatment with chlorambucil. JAMA 197: 90, 1966. CrossrefMedlineGoogle Scholar61. REINHARDPARKERKISSANE EHCJ: Clinicopathologic Conference: Wegener's granulomatosis. Amer. J. Med. 35: 384, 1963. CrossrefMedlineGoogle Scholar62. BETHLENFALVAYNUSYNOWITZ NCML: Temporal arteritis; a rarity in the young adult. Arch. Intern. Med. (Chicago) 114: 487, 1964. CrossrefMedlineGoogle Scholar63. BALMFORTH GV: Temporal arteritis and renal failure. Arch. Intern. Med. (Chicago) 113: 230, 1964. CrossrefMedlineGoogle Scholar64. SCHEERGROSSMAN RLMA: Immune aspects of the glomerulonephritis associated with pulmonary hemorrhage. Ann. Intern. Med. 60: 1009, 1964. LinkGoogle Scholar65. STURGILLWESTERVELT BCFB: Immunofluorescence studies in a case of Goodpasture's syndrome. JAMA 194: 914, 1965. CrossrefMedlineGoogle Scholar66. DUNCANDRUMMONDMICHAELVERNIER DAKNAFRL: Pulmonary hemorrhage and glomerulonephritis. Report of six cases and study of the renal lesion by the fluorescent antibody technique and electron microscopy. Ann. Intern. Med. 62: 920, 1965. LinkGoogle Scholar67. HIRSCHAIKATBASU MSBKAK: Takayasu's arteritis. Report of five cases with immunologic studies. Bull. Hopkins Hosp. 115: 29, 1964. MedlineGoogle Scholar68. RODNAN GP: The natural history of progressive systemic sclerosis (diffuse scleroderma). Bull. Rheum. Dis. 13: 301, 1963. MedlineGoogle Scholar69. SACKNERAKGUNKIMBELLEWIS MANPDH: The pathophysiology of scleroderma involving the heart and respiratory system. Ann. Intern. Med. 60: 611, 1964. LinkGoogle Scholar70. WILSONRODNANROBIN RJGPED: An early pulmonary physiologic abnormality in progressive systemic sclerosis (diffuse scleroderma). Amer. J. Med. 36: 361, 1964. CrossrefMedlineGoogle Scholar71. LAMBIEDUFF JAIF: Familial occurrence of dermatomyositis. Case reports and a family survey. Ann. Intern. Med. 59: 839, 1963. LinkGoogle Scholar72. BARWICKWALTON DDJN: Polymyositis. Amer. J. Med. 35: 646, 1963. CrossrefMedlineGoogle Scholar73. CURTISHECKAMANWHEELER ACJHAH: Study of the autoimmune reaction in dermatomyositis. JAMA 178: 571, 1961. CrossrefMedlineGoogle Scholar74. CASPARYGUBBAYSTERN EASSGM: Circulating antibodies in polymyositis and other muscle-wasting disorders. Lancet 2: 941, 1964. CrossrefMedlineGoogle Scholar75. COOKROSENBANKER CDFSBQ: Dermatomyositis and focal scleroderma. Pediat. Clin. N. Amer. 10: 979, 1963. CrossrefMedlineGoogle Scholar76. PEARSON CM: Patterns of polymyositis and their responses to treatment. Ann. Intern. Med. 59: 827, 1963. LinkGoogle Scholar77. VANSELOWDODSONANGELLDUFF NAVNDCIF: A clinical study of Sjögren's syndrome. Ann. Intern. Med. 58: 124, 1963. LinkGoogle Scholar78. BLOCHBUCHANANWOHLBUNIM KJWWMJJJ: Sjögren's syndrome. A clinical, pathological, and serological study of sixty-two cases. Medicine (Balt.) 44: 187, 1965. CrossrefMedlineGoogle Scholar79. TALALBUNIM NJJ: The development of malignant lymphoma in the course of Sjögren's syndrome. Amer. J. Med. 36: 529, 1964. CrossrefMedlineGoogle Scholar80. KAHNMERRITTWOHLORLOFF MADMJJ: Renal concentrating defect in Sjögren's syndrome. Ann. Intern. Med. 56: 883, 1962. LinkGoogle Scholar81. SHEARNTU MAWH: Nephrogenic diabetic insipidus and other defects of renal tubular function in Sjögren's syndrome. Amer. J. Med. 39: 312, 1965. CrossrefMedlineGoogle Scholar82. FENSTERBUCHANANLASTERBUNIM LFWWLJJ: Studies of pancreatic function in Sjögren's syndrome. Ann. Intern. Med. 61: 498, 1964. LinkGoogle Scholar83. LENOCHBRÉMOVÁKAŇKOVÁSTREDABALÍK FADAJ: The relation of Sjögren's syndrome to rheumatoid arthritis. Acta Rheum. Scand. 10: 297, 1964. CrossrefMedlineGoogle Scholar84. GOODRÖTSTEINMAZZITELLO RAJWF: The simultaneous occurrence of rheumatoid arthritis and agammaglobulinemia. J. Lab. Clin. Med. 49: 343, 1957. MedlineGoogle Scholar85. FUDENBERG HH: Immunologic deficiency, autoimmune disease, and lymphoma: observations, implications, and speculations. Arthritis Rheum. 9: 464, 1966. CrossrefMedlineGoogle Scholar86. PIELPHIBBS CFRH: The hemolyticuremic syndrome. Pediat. Clin. N. Amer. 13: 295, 1966. CrossrefGoogle Scholar87. LEVINESHEARN SMA: Thrombotic thrombocytopenic purpura and systemic lupus erythematosus. Arch. Intern. Med. (Chicago) 113: 826, 1964. CrossrefMedlineGoogle Scholar88. AMOROSIULTMANN ELJE: Thrombotic thrombocytopenic purpura: report of 16 cases and review of the literature. Medicine (Balt.) 45: 139, 1966. CrossrefGoogle Scholar89. DAVISONSPIERAPLOTZ SHCM: Polymyalgia rheumatica. Arthritis Rheum. 9: 18, 1966. CrossrefMedlineGoogle Scholar90. NUESSLEMILLERNORMAN WFHEFC: Polymyalgia rheumatica, giant-cell arteritis and blindness: a review and case report. J. Amer. Geriat. Soc. 14: 566, 1966. CrossrefMedlineGoogle Scholar91. KAPLANBOLANDERAKITABLAIR MHRLJ: Presence of bound immunoglobulins and complement in the myocardium in acute rheumatic fever. Association with cardiac failure. New Eng. J. Med. 271: 637, 1964. CrossrefMedlineGoogle Scholar92. HESSFINKTARANTAZIFF EVCWAM: Heart muscle antibodies in rheumatic fever and other diseases. J. Clin. Invest. 43: 886, 1964. CrossrefMedlineGoogle Scholar93. KLIBANOFFFRIEDENSPAGNUOLOFEINSTEIN EJMAR: "Rheumatic activity." A clinicopathologic correlation. JAMA 195: 895, 1966. CrossrefMedlineGoogle Scholar94. FEINSTEINSTERNSPAGNUOLO AREKM: The prognosis of acute rheumatic fever. Amer. Heart J. 68: 817, 1964. CrossrefMedlineGoogle Scholar95. ALBAMEPSTEINFEINSTEINGAVRINJONASKLEINBERGSIMPSONSPAGNUOLOSTOLLERMANTARANTATURSKYWOOD BJAARJBSERMGHAEHF: Rheumatic fever in children and adolescents: a long-term epidemiologic study of subsequent prophylaxis, streptococcal infections, and clinical sequelae. Ann. Intern. Med. 60 (suppl. 1): 1, 1964. MedlineGoogle Scholar96. LONDONBLAND MGJH: Ankylosing spondylitis with subcutaneous nodules. Report of a case. New Eng. J. Med. 268: 991, 1963. CrossrefGoogle Scholar97. KARTENDITATAMCEWENTANNER IDCM: A family study of rheumatoid (ankylosing) spondylitis. Arthritis Rheum. 5: 131, 1962. CrossrefMedlineGoogle Scholar98. ANSELLWIGLEY BMRA: Arthritic manifestations in regional enteritis. Ann. Rheum. Dis. 23: 64, 1964. CrossrefMedlineGoogle Scholar99. KELLYWEISIGER JJBB: The arthritis of Whipple's disease. Arthritis Rheum. 6: 615, 1963. CrossrefMedlineGoogle Scholar100. BAKERGOLDINGTHOMPSON HDNM: Psoriasis and arthritis. Ann. Intern. Med. 58: 909, 1963. LinkGoogle Scholar101. WRIGHTLUMSDENLUNTZSEVELTRUELOVE RKMHDSC: Abnormalities of the sacro-iliac joints and uveitis in ulcerative colitis. Quart. J. Med. 34: 229, 1965. MedlineGoogle Scholar102. BENEDEKZAWADZKI TGZA: Ankylosing spondylitis with ulcerative colitis and amyloidosis: report of a case and review of the literature. Amer. J. Med. 40: 431, 1966. CrossrefGoogle Scholar103. DAVIDSONBAGGENSTOSSSLOCUMBDAUGHERTY PAHCHGW: Cardiac and aortic lesions in rheumatoid spondylitis. Mayo Clin. Proc. 38: 427, 1963. Google Scholar104. JULKUNENLUOMANMÄKI HK: Complete heart block in rheumatoid (ankylosing) spondylitis. Acta Med. Scand. 176: 401, 1964. CrossrefMedlineGoogle Scholar105. MILLERSPROULE JMBJ: Pulmonary function in ankylosing spondylitis. Amer. Rev. Resp. Dis. 90: 376, 1964. MedlineGoogle Scholar106. BLACKO'BRIEN RLWM: Observations on psoriatic arthritis. AIR 7: 44, 1964. Google Scholar107. CLAUSMCEWENBRUNNERTSAMPARLIS GCTG: Microbiological studies of Reiter's disease. Brit. J. Vener. Dis. 40: 170, 1964. MedlineGoogle Scholar108. ENGLEMANBARNESJONESSCHACHTERMEYER EPMGJPJKF: Arthritis associated with bedsonia infection(abstract). Arthritis Rheum. 9: 502, 1966. Google Scholar109. SCHACHTERBARNESJONESENGLEMANMEYER JMGJPEPKF: Isolation of bedsoniae from the joints of patients with Reiter's syndrome. Proc. Soc. Exp. Biol. Med. 122: 283, 1966. CrossrefMedlineGoogle Scholar110. JONESSCHACHTERMEYER JPJKF: Experimental bedsonia arthritis. Arthritis Rheum. 9: 515, 1966. Google Scholar111. NORTONSTORZ WLJ: Light and electron microscopic studies of synovium from sheep polyarthritis caused by an agent of the psittacosis-lymphogranuloma venereum-trachoma group (abstract). Ibid., p. 528. Google Scholar112. RODNANBENEDEKSHAVERFENNELL GPTGJARH: Reiter's syndrome and aortic insufficiency. JAMA 189: 889, 1964. CrossrefMedlineGoogle Scholar113. WRIGHTREED VWB: The link between Reiter's syndrome and psoriatic arthritis. Ann. Rheum. Dis. 23: 12, 1964. CrossrefMedlineGoogle Scholar114. PETERPEARSONMARMOR JBCML: Erosive osteoarthritis of the hands. Arthritis Rheum. 9: 365, 1966. CrossrefMedlineGoogle Scholar115. GAULHOFER-DE KLERCKVAN DAN EHG: Septic complications in rheumatoid arthritis. Acta Rheum. Scand. 9: 254, 1963. CrossrefMedlineGoogle Scholar116. GOOBARCLARK JEGM: Rheumatological manifestations of gonorrhea. AIR 7: 1, 1964. Google Scholar117. HESSHUNTERZIFF EVDKM: Gonococcal antibodies in acute arthritis. JAMA 191: 531, 1965. CrossrefMedlineGoogle Scholar118. YANEZTHOMPSONMIKKELSENBARTHOLOMEW JEGRWMLE: Rubella arthritis. Ann. Intern. Med. 64: 772, 1966. LinkGoogle Scholar119. HILDEBRANDTMAASSAB HMHF: Rubella synovitis in a one-year-old patient. New Eng. J. Med. 274: 1428, 1966. CrossrefMedlineGoogle Scholar120. GUTMAN AB (editor): Proceedings of conference on gout and purine metabolism, 1964. Arthritis Rheum. 8: 599, 1965. MedlineGoogle Scholar121. MCCARTY DJ: The pendulum of progress in gout: from crystals to hyperuricemia and back. Arthritis Rheum. 7: 534, 1964. CrossrefMedlineGoogle Scholar122. MALAWISTA SE: Sols, gels, and colchicine: a common formulation for the effects of colchicine in gouty inflammation and on cell division. Ibid., p. 325. Google Scholar123. MIKKELSENDODGEVALKENBURG WMHJH: The distribution of serum uric acid values in a population unselected as to gout or hyperuricemia: Tecumseh, Michigan 1959-1960. Amer. J. Med. 39: 242, 1965. CrossrefMedlineGoogle Scholar124. MAGASANIK B: Regulation of the biosynthesis and interconversion of purine nucleotides. Arthritis Rheum. 8: 610, 1965. CrossrefMedlineGoogle Scholar125. WYNGAARDEN JB: The overproduction of uric acid in primary gout. Ibid., p. 648. Google Scholar126. GUTMANYÜ ABTF: An abnormality of glutamine metabolism in primary gout. Amer. J. Med. 35: 820, 1963. CrossrefMedlineGoogle Scholar127. GUTMANYÜ ABTF: Urinary ammonium excretion in primary gout. J. Clin. Invest. 44: 1474, 1965. CrossrefMedlineGoogle Scholar128. POLLAKMATTENHEIMER VEH: Glutaminase activity in the kidney in gout. J. Lab. Clin. Med. 66: 564, 1965. MedlineGoogle Scholar129. DUNNBROOKSMAUSNERRODNANCOBB JPGWJGPS: Social class gradient of serum uric acid levels in males. JAMA 185: 431, 1963. CrossrefGoogle Scholar130. DECKER JL: Hyperuricemia associated with uremia. Arthritis Rheum. 8: 840, 1965. CrossrefMedlineGoogle Scholar131. GONICKRUBINIGLEASONSOMMERS HCMEIOSC: The renal lesion in gout. Ann. Intern. Med. 62: 667, 1965. LinkGoogle Scholar132. OGRYZLO MA: Drugs for gout. Canad. Med. Ass. J. 90: 589, 1964. MedlineGoogle Scholar133. RUNDLESMETZSILBERMAN RWENHR: Allopurinol in the treatment of gout. Ann. Intern. Med. 64: 229, 1966. LinkGoogle Scholar134. MCCARTYGATTER DJRA: Pseudogout syndrome (articular Chondrocalcinosis). Bull. Rheum. Dis. 14: 331, 1964. Google Scholar135. GOOD AE: Acromegalic arthropathy. A case report. Arthritis Rheum. 7: 65, 1964. CrossrefMedlineGoogle Scholar136. MORTADAIMAM AIZ: Virus aetiology of Behçet's syndrome. Brit. J. Ophthal. 48: 250, 1964. CrossrefMedlineGoogle Scholar137. SIGELLARSON NR: Behçet's syndrome. A case with benign pericarditis and recurrent neurologic involvement treated with adrenal steroids. Arch. Intern. Med. (Chicago) 115: 203, 1965. CrossrefMedlineGoogle Scholar138. HELLERGAFNIMICHAELISHAHINSOHAREHRLICHKARTENSOKOLOFF HJDNEGIL: The arthritis of familial Mediterranean fever (FMF). Arthritis Rheum. 9: 1, 1966. CrossrefMedlineGoogle Scholar139. SCHUMACHER HR: Hemochromatosis and arthritis. Arthritis Rheum. 7: 41, 1964. CrossrefMedlineGoogle Scholar140. FALLSFORDASHWORTHCARTER WFKLCTNW: Renal vasculitis in a nonfatal case of Henoch-Schönlein purpura. Ann. Intern. Med. 64: 1276, 1966. LinkGoogle Scholar141. GILBERTDA SILVA EFAQ: Henoch-Schönlein purpura: report of a fatal case with gastro-intestinal hemorrhage and necrosis. Clin. Pediat. 5: 181, 1966. CrossrefMedlineGoogle Scholar142. NESTEROV AI: The clinical course of Kashin-Beck disease. Arthritis Rheum. 7: 29, 1964. CrossrefMedlineGoogle Scholar143. O'BRIENLA DUBUNIM WMBNJJ: Biochemical, pathologic and clinical aspects of alcaptonuria, ochronosis and ochronotic arthropathy. Review of world literature (1584-1962). Amer. J. Med. 34: 813, 1963. CrossrefGoogle Scholar144. KAYESONES RLDA: Relapsing polychondritis. Clinical and pathologic features in fourteen cases. Ann. Intern. Med. 60: 653, 1964. LinkGoogle Scholar145. KAPLAN H: Sarcoid arthritis. A review. Arch. Intern. Med. (Chicago) 112: 924, 1963. CrossrefMedlineGoogle Scholar146. SOKOLOFFBUNIM LJJ: Clinical and pathological studies of joint involvement in sarcoidosis. New Eng. J. Med. 260: 841, 1959. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: San Francisco and Oakland, CaliforniaFrom the Rheumatic Disease Group, Department of Medicine, University of California School of Medicine, San Francisco, and the Department of Medicine, the Permanente Medical Group, Kaiser Foundation Hospital, Oakland, Calif.Requests for reprints should be addressed to Ephraim P. Engleman, M.D., Rheumatic Disease Group—1088-M, Department of Medicine, University of California Medical Center, San Francisco, Calif. 94122. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byParathyroid adenoma an unusual presentationPolymeric Salicylic Acid DerivativesRheumatische und Andere Erkrankungen der GelenkeRheumatoid ArthritisRheumatische und Andere Erkrankungen der GelenkeSalivary gland function in sarcoidosisRecent Advances in Rheumatic Diseases: 1967 Through 1969RICHARD H. FERGUSON, M.D., F.A.C.P., JOHN W. WORTHINGTON, M.D., F.A.C.P.Viral ArthritisJAMES W. SMITH, M.D., JAY P. SANFORD, M.D., F.A.C.P. 1 January 1967Volume 66, Issue 1Page: 199-220KeywordsArthritisEtiologyHospital medicineRheumatoid arthritisRheumatology Issue Published: 1 January 1967 PDF downloadLoading ...