Hypercalcemia and Hypertension
Authors: Jerry M. Earll, Neil A. Kurtzman, Robert H. Moser
Journal: Annals of Internal Medicine (1966)

Case Studies1 February 1966Hypercalcemia and HypertensionJERRY M. EARLL, NEIL A. KURTZMAN, ROBERT H. MOSERJERRY M. EARLL, NEIL A. KURTZMAN, ROBERT H. MOSERAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-64-2-378 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptHypertension as a sign of hypercalcemia has received little emphasis in the literature. Many current textbooks of medicine and endocrinology fail to mention the association while stressing rarer manifestations of hypercalcemia such as pancreatitis. This paper reviews recent experience with three consecutive patients with hypercalcemia and reversible hypertension. Recent experimental evidence confirming the importance of calcium ion concentration on peripheral vascular tone is discussed.CASE REPORTSCASE 1A 24-year-old Negro man underwent a subtotal thyroidectomy in May, 1963, for Graves' disease. Postoperatively he developed hypoparathyroidism which was treated with vitamin D and calcium lactate. He was admitted to the...References1. LEMANNDONATELLI JAA: Calcium intoxication due to primary hyperparathyroidism (a medical and surgical emergency). Ann. Intern. Med. 60: 447, 1964. LinkGoogle Scholar2. THOMASWISWALLCONNORHOWARD WCJGTBJE: Hypercalcemic crisis due to hyperparathyroidism. Amer. J. Med. 24: 229, 1958. CrossrefMedlineGoogle Scholar3. COPE O: Hyperparathyroidism: diagnosis and management. Amer. J. Surg. 99: 394, 1960. CrossrefMedlineGoogle Scholar4. MOORESMITH WTLH: Experience with a calcium infusion test in parathyroid disease. Metabolism 12: 447, 1963. Google Scholar5. OVERBECKMOLNARHADDY HWJIFJ: Resistance to blood flow through the vascular bed of the dog forelimb (local effects of sodium, potassium, calcium, magnesium, acetate, hypertonicity and hypotonicity). Amer. J. Cardiol. 8: 533, 1961. CrossrefMedlineGoogle Scholar6. 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EARLL; NEIL A. KURTZMAN; ROBERT H. MOSERAffiliations: El Paso, TexasFrom the Department of Medicine, William Beaumont General Hospital, El Paso, Tex.Requests for reprints should be addressed to Colonel Robert H. Moser, MC, Department of Medicine, William Beaumont General Hospital, El Paso, Tex. 79920. 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