Neurologic Manifestations of Essential Thrombocythemia
Authors: JAMES P. CROWLEY
Journal: Annals of Internal Medicine (1984)

Letters and Corrections1 February 1984Neurologic Manifestations of Essential ThrombocythemiaJAMES P. CROWLEY, M.D.JAMES P. CROWLEY, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-100-2-316_3 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: I read with interest the recent report (1) on the neurologic manifestations of essential thrombocythemia. From their finding that 21 of 33 patients with essential thrombocythemia had neurologic manifestations, the authors conclude that neurologic complications are common in patients with this disease. However, as the authors indicate, many patients who have evidence on bone marrow examination of myeloproliferation and an elevated platelet count do not have any problem with thrombosis or neurologic complaints. What surely must be one of the highest platelet counts ever recorded in the literature (14 X 106/uL) was seen in a patient at...References1. JABAILYILANDLASZLO JHJ. Neurologic manifestations of essential thrombocythemia. Ann Intern Med. 1983;99:513-8. LinkGoogle Scholar2. FANGERCELLALITCHMAN HLH. Thrombocythemia: report of three cases and review of literature. N Engl J Med. 1954;250:456. CrossrefMedlineGoogle Scholar1. JABAILYILANDLASZLO JHJ. Neurologic manifestations of essential thrombocythemia. Ann Intern Med. 1983;99:513-8. LinkGoogle Scholar2. COHENWIERNIKWALKER RPM. Acute nonlymphocytic leukemia associated with nitrosourea chemotherapy: report of two cases. Cancer Treat Rep. 1976;60:1257-61. MedlineGoogle Scholar3. VOGL S. Acute leukemia complicating treatment of glioblastoma multiforme. Cancer. 1978;41:333-6. CrossrefMedlineGoogle Scholar4. UPHOUSE W. Case report: acute leukemia after semustine (methyl-CCNU) therapy. Cancer Treat Rep. 1982;66:1593-4. MedlineGoogle Scholar1. JABAILYILANDLASZLO JHJ. Neurologic manifestations of essential thrombocythemia. Ann Intern Med. 1983;99:513-8. LinkGoogle Scholar2. ILANDLASZLOPETERSON HJP. Essential thrombocythemia: clinical and laboratory characteristics at presentation. Trans Assoc Am Physicians. (In press). Google Scholar3. SCHAFER A. Deficiency of platelet lipoxygenase activity in myeloproliferative disorders. N Engl J Med. 1982;306:381-6. CrossrefMedlineGoogle Scholar4. PARETIGUGLIOTTAMANNUCCIGUARINIMANNUCCI FLLAP. Biochemical and metabolic aspects of platelet dysfunction in chronic myeloproliferative disorders. Thromb Haemostas. 1982;47:84-9. CrossrefMedlineGoogle Scholar5. HATTORISANADANAGAYAMASHIBATAOKUMA AMRAM. Aspirin ingestion in primary thrombocythemia. Thromb Haemostas. 1982;48:72-5. CrossrefMedlineGoogle Scholar6. SCHILSKYERLICHMAN RC. Late complications of chemotherapy: infertility and carcinogenesis. In: CHABNER BA, ed. Pharmacologic Principles of Cancer Treatment. Philadelphia: W.B. Saunders Co.; 1982:109-31. Google Scholar7. MURANYI-KOVACSRUDALI IG. Comparative study of carcinogenic activity of hydroxyurea and urethane in XVII/G mice. Eur J Clin Biol Res. 1972;17:93-5. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByControlled and uncontrolled thrombocytosis.Its clinical role in essential thrombocythemia 1 February 1984Volume 100, Issue 2Page: 316-317KeywordsBone marrowPlateletsThrombocytosisThrombosis Issue Published: 1 February 1984 PDF DownloadLoading ...