tbuckley/cabot-search huggingface dataset:
Psychiatric Family Consultations
Authors: JEROME V. TREUSCH
Journal: Annals of Internal Medicine (1967)

Article1 February 1967Psychiatric Family ConsultationsA Practical Approach in Family Practice for the Personal PhysicianJEROME V. TREUSCH, M.D., F.A.C.P., MARTIN GROTJAHN, M.D.JEROME V. TREUSCH, M.D., F.A.C.P.Search for more papers by this author, MARTIN GROTJAHN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-66-2-295 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn 1954 cooperative studies were begun by a psychiatrist (M. G.) and an internist (J. V. T.) that led to a new technique of psychiatric consultation (1). These consultations were conducted in the internist's office with the internist present. Instead of being sent into the new and foreboding environment of a psychiatrist's office, the patient would come to the familiar situation of his internist's office where he was more at ease and had less tendency to develop special defenses.Our original consultations involved three individuals: the patient, the consulting psychiatrist, who as guest in the internist's office was the central...References Other References1. GROTJAHNTREUSCH MJV: A new technique of psychosomatic consultations. Some illustrations of teamwork between an internist and a psychiatrist. A practical approach to psychosomatic medicine. Psychoanal. Rev. 44: 176, 1957. MedlineGoogle Scholar2. GROTJAHN M: Psychoanalysis and the Family Neurosis. W. W. Norton and Co., Inc., New York, 1960, pp. 149, 150. Google Scholar3. DEUTSCH F: The associative anamnesis. Psychoanal. Quart. 8: 354, 1939. CrossrefGoogle Scholar4. BINGER C: The Doctor's Job. W. W. Norton and Co., Inc., New York, 1945. A most sensitive and deep-going study of the relationship between medicine and psychiatry. Google Scholar5. BALINT M: The Doctor, His Patient, and the Illness. International Universities Press, Inc., New York, 1955. And, Training general practitioners in psychotherapy. Brit. Med. J. 1: 115, 1954. About the implications of modern psychiatry to general practitioners. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Los Angeles, CaliforniaFrom the UCLA School of Medicine and the University of Southern California School of Medicine, Los Angeles, Calif.This work was presented at the Forty-seventh Annual Session of the American College of Physicians, New York, N. Y., April 21, 1966.Requests for reprints should be addressed to Jerome V. Treusch, M.D., 405 N. Bedford Dr., Beverly Hills, Calif. 90210. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByPsychological Reaction to Hospitalization and Illness in the Emergency DepartmentPsychiatric Consultation: Part I. A General Systems ApproachBrief Psychotherapy 1 February 1967Volume 66, Issue 2Page: 295-300KeywordsAlcoholsHygiene Issue Published: 1 February 1967 PDF DownloadLoading ...
Neuronal proteins are novel components of podocyte major processes and their expression in glomerular crescents supports their role in crescent formation
Authors: Laleh Sistani, Patricia Q. Rodriguez, Kjell Hultenby, Mathias Uhlen, Christer Betsholtz, Hannu Jalanko, Karl Tryggvason, Annika Wernerson, Jaakko Patrakka
Journal: Kidney International (2012)
THE TREATMENT OF DRUG ADDICTION: PRIVATE PRACTICE EXPERIENCE WITH 84 ADDICTS
Authors: MANUEL M. PEARSON, RALPH B. LITTLE
Journal: American Journal of Psychiatry (1965)

The scope of this report covers 30 years of private practice experience by two psychiatrists who treated 84 drug addicts, emphasizing the diagnostic features, correlating therapeutic principles, the prognosis and the results of therapy. Each patient was treated for the problem of drug addiction, and therapy was not directed toward the particular addicting agent. The same psychotherapeutic principles apply for addiction to narcotics, sedatives, tranquilizers or stimulants. Special emphasis was placed on the addictogenic feature of a disturbed human interrelationship as a significant etiologic factor. Fewer sociopathic personality disturbances and better motivated patients constituted our private practice experience. There is a definite relationship between the diagnosis and the prognosis. The results set aside the generally accepted very bad prognosis for addiction problems. This report is designed to fill the present gap of reports regarding treatment methods and results of therapy for drug addiction. We believe that the following of our basic therapeutic principles will materially increase the competence of the psychiatrist to handle his addicted patients.
Ambient Temperature and Morbidity: A Review of Epidemiological Evidence
Authors: Xiaofang Ye, Rodney Wolff, Weiwei Yu, Pavla Vaneckova, Xiaochuan Pan, Shilu Tong
Journal: Environmental Health Perspectives (2011)

In this paper, we review the epidemiological evidence on the relationship between ambient temperature and morbidity. We assessed the methodological issues in previous studies and proposed future research directions.
Genetic control of antibody production during collagen induced arthritis development in heterogeneous stock mice
Authors: Michael Förster, Bruno Raposo, Diana Ekman, Dorota Klaczkowska, Marjan Popovic, Kutty Selva Nandakumar, Emma Ahlqvist, Rikard Holmdahl
Journal: Annals of the Rheumatic Diseases (2012)

<h3>Objectives</h3> The genetic factors that drive pathogenic autoantibody formation in rheumatoid arthritis (RA) and its experimental models need to be elucidated in order to understand the aetiology of the disease and improve possibilities for therapeutic intervention. For that reason, the authors made a genome wide analysis of quantitative trait loci controlling autoantibody production towards type II collagen (AC2A), anticitrullinated protein antibodies (ACPA) and rheumatoid factors (RF) in the collagen-induced arthritis (CIA) model in mice. <h3>Methods</h3> To identify the most important loci controlling autoantibody production, the authors made use of a heterogeneous stock (HS) derived inbred-outbred mouse population, with contribution of eight common inbred mouse strains backcrossed to C57BL/10.Q (BQ). Thus, all mice express the arthritis permissive MHC class II gene Aq, which is critical for a type II collagen (CII) immune response. These mice were immunised with CII and subsequently serologically monitored for antibody development by standard ELISA. <h3>Results</h3> With this study, the authors have identified numerous loci controlling formation of anti-CII IgG response of different isotypes, antibodies to major collagen epitopes (C1, U1, J1 and F4), to a citrullinated CII peptide (CitC1) and RF. The AC2A, ACPA and RF responses were found to be controlled by distinct genes. AC2A epitope specific response was also controlled by a distinct set of genes, however an important locus was the Immunoglobulin heavy chain (IgH) locus. Lastly, arthritis suppressive antibodies against F4 were uniquely genetically controlled. <h3>Conclusion</h3> Here the authors report the genome wide association analysis of the antibody response during CIA development in mice using a HS cohort. AC2A, ACPA and RF antibodies were all controlled by multiple and unique loci. Clearly, our results indicate, that antibody specificity is also determined by non-MHC genes. Surprisingly, only a single locus was found to control AC2A response and clinical disease simultaneously.
FDA finds breast implants to be safe but calls for better follow-up
Authors: N. Stafford
Journal: BMJ (2011)

Silicone gel breast implants are safe, the US Food and Drug Administration announced at a meeting last week that reviewed the latest evidence. But it warned that the two major US manufacturers are failing to follow up enough women with breast implants.

“Based on the totality of data currently available to FDA, the agency continues to believe that silicone breast implants currently approved are safe and effective for their intended use,” an FDA spokeswoman, Erica Jefferson, told the BMJ . But she noted that they “are not lifetime devices.” 

Ms Jefferson noted that the FDA “emphasised again that silicone gel breast implants are associated with a significant complication rate. But generally speaking we believe that the benefits and risks are sufficiently understood and can be used to help women make informed decisions.” She was speaking at a meeting of the FDA’s general and plastic surgery …
NON-CANONICAL ANGIOTENSIN II TYPE 1A RECEPTOR-MEDIATED, BETA-ARRESTIN2-DEPENDENT SIGNALING CONTRIBUTES TO THORACIC AORTIC ANEURYSM FORMATION IN A MURINE MODEL OF MARFAN SYNDROME
Authors: James Wisler, Emily Harris, Michael Raisch, Lan Mao, Jihee Kim, Howard Rockman, Robert Lefkowitz
Journal: Journal of the American College of Cardiology (2014)
An optimal therapeutic expression level is crucial for suicide gene therapy for hepatic metastatic cancer in mice
Authors: Yasuhiro Terazaki, Shojiro Yano, Kentaro Yuge, Satoshi Nagano, Mari Fukunaga, Sheng Z. Guo, Setsuro Komiya, Kazuo Shirouzu, Ken-ichiro Kosai
Journal: Hepatology (2003)

The most serious problem in current gene therapy is discrepancies between experimental data and actual clinical outcomes, which may be due to insufficient analyses and/or inappropriate animal models. We have explored suicide gene therapy by using various clinically relevant animal models and doubt the clinical use of maximal suicide gene expression, which has been generally recommended. To explore this subject further, we studied what expression level of suicide gene and what promoter led to the maximal clinical benefit in the case of hepatic metastatic cancer in mice. Therapeutic and adverse side effects of 4 adenoviral vectors that express herpes simplex virus thymidine kinase (HSV-tk) under different promoters were scrupulously investigated in 2 mouse models of hepatic metastasis of gastric cancer that possess clinical characteristics. Surprisingly, increases in HSV-tk expression beyond a certain point, achieved by the Rous sarcoma virus long terminal repeat promoter, not only enhanced the adverse side effects of lethal hepatotoxicity and ganciclovir-independent cytotoxicity but also failed to further increase therapeutic potential. Moreover, the carcinoembryonic antigen (CEA) tumor-specific promoter, the therapeutic potential of which had been underestimated, was much more useful—even in the case of low CEA-producing cancer—than had been previously reported. In conclusion, the optimal therapeutic expression level of a suicide gene is a novel concept and a crucial factor for successful cancer gene therapy. The present results, which contradict those of previous studies, alert researchers about possible problems with ongoing and future clinical trials that lack this concept.
Hype in the BMJ
Authors: B. K Howells
Journal: BMJ (1992)

Proportion of general practitioners indicating their wish for information in discharge letters conceming various aspects of their patients' attendance at accident and emergency departments No (%) of practitioners requiring information on aspect Aspect of attendance (n= 213) Mode of referral 194 (91) General practitioner diagnosis (prior to referral) 134 (63) Clinical findings in accident and emergency*: All positive findings 115 (54) All negative findings 57 (27) Only relevant findings 109 (51) Results of investigations in accident and emergency: Haematology 187 (88) Biochemistry 183 (86) x Ray 191 (90) Diagnosis in accident and emergency 208 (98) Treatment in accident and emergency 202 (95) Outcome (admit or discharge) 203 (95) Treatment suggested for general practitioner 192 (90) Follow up arrangements 200 (94) Information given to patient 175 (82) Information to general practitioner**: On all patients 160 (75) Only those sent home 53 (25)*Actual question: Would you like to know all positive findings?all negative findings?only "relevant" findings?other (please specify)?Some respondents replied to more than one category.
Risk of death from cancer and ischaemic heart disease in meat and non-meat eaters
Authors: M Thorogood, J Mann, P Appleby, K McPherson
Journal: BMJ (1994)

<h3>Abstract</h3> <b>Objective</b>: To investigate the health consequences of a vegetarian diet by examining the 12 year mortality of non-meat eaters and meat eating controls. <b>Design</b>: Prospective observational study in which members of the non-meat eating cohort were asked to nominate friends or relatives as controls. <b>Setting</b>: United Kingdom. <b>Subjects</b>: 6115 non-meat eaters identified through the Vegetarian Society of the United Kingdom and the news media (mean (SD) age 38.7 (16.8) years) and 5015 controls who were meat eaters (39.3 (15.4) years). <b>Main outcome measures</b>: Standardised mortality ratios for cancer, ischaemic heart disease, and total mortality in the two cohorts and death rate ratio in the non-meat eaters compared with meat eaters after adjustment for potentially confounding variables. <b>Results</b>: Standardised mortality ratios (taking the value among the general population as 100) for ischaemic heart disease were 51 (95% confidence interval 38 to 66) for meat eaters and 28 (20 to 38) for non- meat eaters (P&lt;0.01). Values for all cancers were 80 (64 to 98) and 50 (39 to 62) for meat eaters20and non-meat eaters respectively. After adjustment20for the effects of smoking, body mass index, and socioeconomic status death rate ratios in non-meat eaters compared with meat eaters were 0.72 (0.47 to 1.10) for ischaemic heart disease and 0.61 (0.44 to 0.84) for all cancers. <b>Conclusions</b>: The reduced mortality from cancer among those not eating meat is not explained by lifestyle related risk factors, which have a low prevalence among vegetarians. No firm conclusion can be made about deaths from ischaemic heart disease. These data do not justify advice to exclude meat from the diet since there are several attributes of a vegetarian diet apart from not eating meat which might reduce the risk.
Nitric oxide metabolites in nasal lavage fluid of patients with house dust mite allergy.
Authors: I M Garrelds, J G van Amsterdam, C de Graaf-in't Veld, R Gerth van Wijk, F J Zijlstra
Journal: Thorax (1995)

BACKGROUND--The role of nitric oxide in the early and late phase of the allergic process was investigated in patients with allergic rhinitis against house dust mite and the effect of fluticasone propionate aqueous nasal spray was determined. METHODS--Production of nitric oxide (measured as nitrite+nitrate) in vivo in nasal mucosa was examined in 24 patients with rhinitis allergic to the house dust mite. In a double blind placebo controlled crossover study fluticasone propionate 200 micrograms aqueous nasal spray was administered twice daily for two weeks. In response to provocation with house dust mite extract (after four basal nasal lavages) nasal lavages were performed every hour for 9.5 hours by washing the nose with saline. In addition, a similar lavage protocol was performed in healthy volunteers with or without challenge with phosphate buffered saline. RESULTS--Nitric oxide is present in nasal lavage fluid in detectable amounts (range 10-50 microM), the level gradually increasing with time in both patients and controls after a decrease during the four basal lavages. Treatment with fluticasone propionate aqueous nasal spray did not affect initial basal production of nitric oxide nor production following provocation with house dust mite extract. CONCLUSIONS--Production of nitric oxide in nasal mucosa determined in sequential nasal washings is not affected by therapeutic doses of intranasal steroids.
2010 Guidelines for Antiretroviral Treatment of HIV From the International AIDS Society–USA Panel
Authors: Heiner C. Bucher, Marcel Wolbers, Kholoud Porter
Journal: JAMA (2010)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Relationship of Left Atrial Volume to Pulmonary Artery and Wedge Pressures in Mitral Stenosis
Authors: LOUIS A. SOLOFF, JACOB ZATUCHNI, GEORGE E. MARK
Journal: Circulation (1957)

The significance of left atrial volume has been studied in 20 consecutive patients with mitral stenosis. Cardiac catheterization was performed and resting pressures in the right atrium, right ventricle, and pulmonary artery, as well as wedge pressure, were determined. Angiocardiography was performed immediately after cardiac catheterization. On the basis of these data the relationship between the estimated left atrial volume and these pressures is stated.
Hypercapnia Enhances the Development of Coughing during Continuous Infusion of Water into the Pharynx
Authors: TAKASHI NISHINO, RISA HASEGAWA, TOHRU IDE, SHIRO ISONO
Journal: American Journal of Respiratory and Critical Care Medicine (1998)

We investigated the effects of increasing CO2 ventilatory drive on the coordination of respiration and reflex swallowing elicited by continuous infusion of distilled water into the pharynx (2.5 ml/min) in 11 normal subjects. Ventilation was monitored using a pneumotachograph and swallowing was recorded by submental electromyogram. The CO2 ventilatory drive was increased by addition of external dead space, while ventilation, the frequency of swallows, and the timing of swallows in relation to the phases of the respiratory cycle were measured at steady-state conditions. We found that the CO2 ventilatory response is not influenced by continuous reflex swallowing but that hypercapnia influences the timing and frequency of these swallows. Signs of aspiration were never observed during continuous infusion of water at eucapnia, but seven of 11 subjects showed laryngeal irritation and/or pending aspiration during hypercapnia, and the incidence of laryngeal irritation was higher the greater the PCO2. Detailed analysis of laryngeal irritations consisting of single coughs in seven subjects revealed that the majority of laryngeal irritations occurred when swallows coincided with expiratory-inspiratory transition or when swallows coincided with inspiration, whereas laryngeal irritation after an expiratory swallow was never observed. These results suggest that the automatic respiratory control system is not influenced by continuous swallowing but that the coordination of swallowing and respiration may be compromised during hypercapnia.
Adverse events with medical devices may go unreported
Authors: N. Baker
Journal: BMJ (2002)

EDITOR—Amoore and Ingram report that 400 people a year are seriously injured or killed as a result of adverse incidents with medical devices.1 We believe that this figure is the tip of the iceberg and that many more cases occur that are simply not recognised. Infectious complications of medical devices are often not considered in the context of reporting, and so the possible lessons that can minimise recurrence remain unlearnt.

One of the most commonly used medical devices in hospital patients are peripheral intravenous …
THORACOPLASTY IN AMERICA AND VISCERAL PLEURECTOMY, WITH REPORT OF A CASE.
Authors: ALEX. HUGH FERGUSON
Journal: JAMA (1897)

When I forwarded the title of my paper to the Chairman of this Section, I had no idea but that I should now have several interesting cases of Schede's operation performed in America to lay before you. Being disappointed by a personal research of the periodicals published in this country, I applied to the American Bureau of Medical Literature, at Washington, D. C., and in due time I received the following reply: "We have been unable to find any case of Schede's operation performed in America." There is no doubt in my mind but that this major operation has been done many times in this country, though not reported. Thoracoplasty, as first done by Schede, is an heroic measure for the otherwise hopeless cases of chronic empyema. It consists in the removal of the chest wall, that is the ribs; intercostal muscles and parietal pleura are extirpated, then curettage of
TEST-RETEST RELIABILITY OF THREE SETUP POSITIONS DURING ISOKINETIC ANKLE INVERSION-EVERSION EXERCISE
Authors: C Gautrey, T Watson, A Mitchell
Journal: British Journal of Sports Medicine (2014)

Background Strength testing of the ankle musculature using the isokinetic dynamometer is often undertaken by sports clinicians and is of great importance for screening, rehabilitation and injury prevention. Injuries such as ankle sprains may be preventable if the risk factors can be addressed; however, the success of such screening procedures depends on the accuracy and reproducibility of the methods used. Objective To determine the test-retest reliability of three setup positions during isokinetic ankle inversion-eversion exercise, and to investigate the effect of setup position on peak torque and total work. Design Randomised test-retest study. Setting University biomechanics laboratory. Participants played at a semi-professional level of soccer. Participants: A convenience sample was used to recruit sixteen healthy male participants. Inclusion criteria included males, aged 18–25 years, who participated in semi-professional soccer and who were right leg dominant. Risk factor assessment Three maximal concentric ankle inversion-eversion repetitions at 60, 120, 180, 240, 300 and 360° · s −1 , during 10° dorsiflexion, neutral dorsiflexion/plantarflexion, and 10° plantarflexion . Set up position and isokinetic speed were the independent variables. Main outcome measure Peak torque and total work in newton metres in the three setup positions. Results The results indicated that the 10° plantarflexion position was the most reliable setup, with ICC results ranging from 0.84–0.95 for peak torque and total work, at speeds 60 through 240°· s −1 , during ankle inversion and eversion. The results also showed significantly greater (P&lt;.0167) peak torque and total work values for the 10° plantarflexion position. Conclusion Clinicians should consider adopting this new ankle setup when screening or rehabilitating athletes as the most reliable results were identified. The 10° plantarflexion position also most accurately represented the peak performance of the muscles tested, as peak torque and total work were maximised in this position.
Sunlight Sensitivity From Oral Contraceptives
Authors: Larry R. Erickson
Journal: JAMA (1968)

Oral contraceptives may cause sunlight sensitivity. An eruption similar to polymorphic light eruption developed in a 31-year-old Negro woman who was taking norethynodrel with mestranol (Enovid E). Symptoms and lesions cleared after stopping the drug administration, only to reappear after trial with other oral contraceptives. Estrogen alone caused the condition to reappear, suggesting that this was the active agent in causing sunlight sensitivity. The "pill" can be added to the growing list of photosensitizing drugs.