Enough Is Enough: Stop Wasting Money on Vitamin and Mineral Supplements
Authors: Eliseo Guallar, Saverio Stranges, Cynthia Mulrow, Lawrence J. Appel, Edgar R. Miller
Journal: Annals of Internal Medicine (2013)

EditorialsDecember 17, 2013Enough Is Enough: Stop Wasting Money on Vitamin and Mineral SupplementsEliseo Guallar, MD, DrPH, Saverio Stranges, MD, PhD, Cynthia Mulrow, MD, MSc, Senior Deputy Editor, Lawrence J. Appel, MD, MPH, and Edgar R. Miller III, MD, PhDEliseo Guallar, MD, DrPHFrom Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; Warwick Medical School, University of Warwick, Coventry, England, United Kingdom; Annals of Internal Medicine, American College of Physicians, Philadelphia, Pennsylvania; and Johns Hopkins School of Medicine, Baltimore, Maryland., Saverio Stranges, MD, PhDFrom Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; Warwick Medical School, University of Warwick, Coventry, England, United Kingdom; Annals of Internal Medicine, American College of Physicians, Philadelphia, Pennsylvania; and Johns Hopkins School of Medicine, Baltimore, Maryland., Cynthia Mulrow, MD, MSc, Senior Deputy EditorFrom Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; Warwick Medical School, University of Warwick, Coventry, England, United Kingdom; Annals of Internal Medicine, American College of Physicians, Philadelphia, Pennsylvania; and Johns Hopkins School of Medicine, Baltimore, Maryland., Lawrence J. Appel, MD, MPHFrom Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; Warwick Medical School, University of Warwick, Coventry, England, United Kingdom; Annals of Internal Medicine, American College of Physicians, Philadelphia, Pennsylvania; and Johns Hopkins School of Medicine, Baltimore, Maryland., and Edgar R. Miller III, MD, PhDFrom Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; Warwick Medical School, University of Warwick, Coventry, England, United Kingdom; Annals of Internal Medicine, American College of Physicians, Philadelphia, Pennsylvania; and Johns Hopkins School of Medicine, Baltimore, Maryland.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-159-12-201312170-00011 SectionsSupplemental MaterialAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail This article has been corrected. The original version (PDF) is appended to this article as a supplement.References1. Fortmann SP, Burda BU, Senger CA, Lin JS, and Whitlock EP. Vitamin and mineral supplements in the primary prevention of cardiovascular disease and cancer: an updated systematic evidence review for the U.S. Preventive Services Task Force. Ann Intern Med. 2013;159:824-34. LinkGoogle Scholar2. Grodstein F, O'Brien J, Kang JH, Dushkes R, Cook NR, Okereke O, et al. Long-term multivitamin supplementation and cognitive function in men. A randomized trial. Ann Intern Med. 2013;159:806-14. LinkGoogle Scholar3. Lin JS, O'Connor E, Rossom RC, Perdue LA, and Eckstrom E. Screening for cognitive impairment in older adults: a systematic review for the U.S. Preventive Services Task Force. Ann Intern Med. 2013;159:601-12 AbstractGoogle Scholar4. Lamas GA, Boineau R, Goertz C, Mark DB, Rosenberg Y, Stylianou M, et al. TACT (Trial to Assess Chelation Therapy) Investigators. Oral high-dose multivitamins and minerals after myocardial infarction. A randomized trial. Ann Intern Med. 2013;159:797-804. LinkGoogle Scholar5. Huang HY, Caballero B, Chang S, Alberg AJ, Semba RD, Schneyer CR, et al. The efficacy and safety of multivitamin and mineral supplement use to prevent cancer and chronic disease in adults: a systematic review for a National Institutes of Health state-of-the-science conference. Ann Intern Med. 2006;145:372-85 LinkGoogle Scholar6. Bjelakovic G, Nikolova D, and Gluud C. Antioxidant supplements to prevent mortality. JAMA. 2013;310:1178-9. [PMID: 24045742] CrossrefMedlineGoogle Scholar7. Miller ER, Pastor-Barriuso R, Dalal D, Riemersma RA, Appel LJ, and Guallar E. Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality. Ann Intern Med. 2005;142:37-46 LinkGoogle Scholar8. Miller ER, Juraschek S, Pastor-Barriuso R, Bazzano LA, Appel LJ, and Guallar E. Meta-analysis of folic acid supplementation trials on risk of cardiovascular disease and risk interaction with baseline homocysteine levels. Am J Cardiol. 2010;106:517-27. [PMID: 20691310] CrossrefMedlineGoogle Scholar9. Gahche J, Bailey R, Burt V, Hughes J, Yetley E, Dwyer J, et al. Dietary supplement use among U.S. adults has increased since NHANES III (1988-1994). NCHS Data Brief. 2011;:1-8. [PMID: 21592424] MedlineGoogle Scholar10. Moyer VA; U.S. Preventive Services Task Force. Vitamin D and calcium supplementation to prevent fractures in adults: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med. 2013;158:691-6 LinkGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; Warwick Medical School, University of Warwick, Coventry, England, United Kingdom; Annals of Internal Medicine, American College of Physicians, Philadelphia, Pennsylvania; and Johns Hopkins School of Medicine, Baltimore, Maryland.Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M13-2593.Corresponding Author: Eliseo Guallar, MD, DrPH, Welch Center for Prevention, Epidemiology and Clinical Research, 2024 East Monument Street, Room 2-645, Baltimore, MD, 21287; e-mail, [email protected].Current Author Addresses: Drs. Guallar, Appel, and Miller: Departments of Epidemiology and Medicine and Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, MD, 21287.Dr. Stranges: Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, United Kingdom.Dr. Mulrow: American College of Physicians, 190 N. Independence Mall West, Philadelphia, PA 19106-1572. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoVitamin and Mineral Supplements in the Primary Prevention of Cardiovascular Disease and Cancer: An Updated Systematic Evidence Review for the U.S. Preventive Services Task Force Stephen P. Fortmann , Brittany U. Burda , Caitlyn A. Senger , Jennifer S. Lin , and Evelyn P. Whitlock Oral High-Dose Multivitamins and Minerals After Myocardial Infarction Gervasio A. Lamas , Robin Boineau , Christine Goertz , Daniel B. Mark , Yves Rosenberg , Mario Stylianou , Theodore Rozema , Richard L. Nahin , Lauren Lindblad , Eldrin F. Lewis , Jeanne Drisko , Kerry L. Lee , and Long-Term Multivitamin Supplementation and Cognitive Function in Men Francine Grodstein , Jacqueline O'Brien , Jae Hee Kang , Rimma Dushkes , Nancy R. Cook , Olivia Okereke , JoAnn E. Manson , Robert J. Glynn , Julie E. Buring , J. Michael Gaziano , and Howard D. Sesso Correction: Stop Wasting Money on Vitamin and Mineral SupplementsEnough Is Enough Balz Frei , Bruce N. Ames , Jeffrey B. Blumberg , and Walter C. Willett Enough Is Enough Irvine Mason Enough Is Enough Deborah Stepp Enough Is Enough Thomas R. Friberg Enough Is Enough Jessica Fargnoli , Joyce Greenleaf , and Melissa Hafner Enough Is Enough Eliseo Guallar , Saverio Stranges , Cynthia Mulrow , Lawrence J. Appel , and Edgar R. Miller III Enough Is Enough Irvine Mason Enough Is Enough Deborah Stepp Enough Is Enough Thomas R. Friberg Enough Is Enough Jessica Fargnoli , Joyce Greenleaf , and Melissa Hafner Enough Is Enough Eliseo Guallar , Saverio Stranges , Cynthia Mulrow , Lawrence J. Appel , and Edgar R. Miller III Enough Is Enough Balz Frei , Bruce N. Ames , Jeffrey B. Blumberg , and Walter C. Willett Metrics Cited ByEnough Is EnoughBalz Frei, PhD, Bruce N. Ames, PhD, Jeffrey B. Blumberg, PhD, and Walter C. Willett, MD, DrPHEnough Is EnoughIrvine Mason, MDEnough Is EnoughDeborah Stepp, RNEnough Is EnoughThomas R. Friberg, MD, MSEnough Is EnoughJessica Fargnoli, MPH, Joyce Greenleaf, MBA, and Melissa Hafner, MPPCorrection: Stop Wasting Money on Vitamin and Mineral Supplements December 17, 2013Volume 159, Issue 12Page: 850-851KeywordsAntioxidantsCalciumCardiovascular diseasesClinical trialsCognitionCognitive impairmentDementiaElderlyFallsFatty acidsFolic acidForecastingMalnutritionMemoryMyocardial infarctionPrevention, policy, and public healthSystematic reviewsVitamin AVitamin DVitamin E ePublished: 17 December 2013 Issue Published: December 17, 2013 CopyrightCopyright © 2013 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...