Recurrent Pheochromocytoma with Recognition of Site of Metastasis by Means of Venous Catheterization
Authors: LOCKHART B. MCGUIRE
Journal: Annals of Internal Medicine (1964)

Case Studies1 January 1964Recurrent Pheochromocytoma with Recognition of Site of Metastasis by Means of Venous CatheterizationA Case StudyLOCKHART B. MCGUIRE, M.D., LAY M. FOX, M.D.LOCKHART B. MCGUIRE, M.D., LAY M. FOX, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-60-1-125 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe presence of pheochromocytoma can be recognized with increasing reliability through the measurement of urinary and blood levels of the catecholamines and their metabolites, in addition to the standard histamine and phentolamine infusion tests (1, 2). Greater portions of the circulating hormones are excreted as 3-methoxy-4-hydroxymandelic acid (VMA), than as epinephrine and norepinephrine. Thus, the measurement of urinary VMA has become widely used to detect high circulating levels of these hormones (3). However, once the presence of such a tumor has been established, the problem of localizing it for the purposes of surgical removal may be a major one. According...References1. VON EULERSTROM USG: Present status of diagnosis and treatment of pheochromocytoma. Circulation 15: 5, 1957. CrossrefMedlineGoogle Scholar2. HUME DM: Pheochromocytoma in the adult and in the child. Amer. J. Surg. 99: 458, 1960. CrossrefMedlineGoogle Scholar3. GITLOWMENDLOWITZKHASSISCOHENSHA SEMSGJ: The diagnosis of pheochromocytoma by the determination of urinary 3-methoxy-4-hydroxymandelic acid. J. Clin. Invest. 39: 221, 1960. CrossrefMedlineGoogle Scholar4. SHERWIN RP: Histopathology of pheochromocytoma. Cancer 12: 311, 1959. CrossrefGoogle Scholar5. WEIL-MALHERBEBONE HHG: Chemical estimation of adrenaline-like substances in blood. Biochem. J. 51: 331, 1952. CrossrefGoogle Scholar6. KVALEROTHMANGERPRIESTLY WFGMWMJT: Present-day diagnosis and treatment of pheochromocytoma: a review of 51 cases. 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BECKERTAUBE FFH: Myocarditis of obscure etiology associated with pregnancy. New Eng. J. Med. 266: 62, 1962. CrossrefMedlineGoogle Scholar14. GILLESPIEOATESCROUTSJOERDSMA LJAJRA: Clinical and chemical studies with alpha-methyldopa in patients with hypertension. Circulation 25: 281, 1962. CrossrefMedlineGoogle Scholar15. SJOERDSMAOATESZALTSMANUDENFRIEND AJAPS: Serotonin synthesis in carcinoid patients. New Eng. J. Med. 263: 585, 1960. CrossrefMedlineGoogle Scholar16. GIFFORDTWEED RWDC: Spurious elevation of urinary catecholamines during therapy with alpha-methyldopa JAMA 182: 493, 1962. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Chelsea, MassachusettsFrom United States Naval Hospital, Chelsea, Massachusetts.Requests for reprints should be addressed to Lockhart B. McGuire, M.D., Department of Internal Medicine, University of Virginia, School of Medicine, Charlottesville, Virginia.Dr. McGuire is a Lieutenant Commander and Dr. Fox is a Commander in the Medical Corps of the United States Naval Reserve. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDiagnostic problems in pheochromocytomaMalignant phaeochromocytoma in children: A case with neurofibromatosis and review of the literatureEpinephrine Fraction of Adrenal Vein Blood in PheochromocytomaMalignant Pheochromocytoma: Clinical Course and TreatmentAdrenal and Extra-Adrenal Pheochromocytomas: Localization by Vena Cava Sampling and Observations on Renal Juxtaglomerular ApparatusPhaeochromocytoma and Other Catecholamine-Producing TumoursMalignant Pheochromocytoma with Pleural Metastasis of Unusually Long DurationBiochemistry of Functional Neural Crest TumorsMyocardial injury from epinephrine overdosageBilateral pheochromocytoma: The application of a plasma catecholamine bioassay for tumor localizationCurrent Experience in the Diagnosis of Pheochromocytoma 1 January 1964Volume 60, Issue 1Page: 125-130KeywordsBlood plasmaCatecholaminesHematologic testsHistamineHormonesHypertensionMetabolitesNorepinephrinePheochromocytomaThorax Issue Published: 1 January 1964 PDF downloadLoading ...