tbuckley/cabot-search huggingface dataset:
REHABILITATION OF THE MENTALLY ILL: IMPACT OF A PROJECT UPON HOSPITAL STRUCTURE
Authors: MILTON GREENBLATT, DAVID LANDY, ROBERT W. HYDE, J. SANBOURNE BOCKOVEN
Journal: American Journal of Psychiatry (1958)

The Rehabilitation Project of the Massachusetts Mental Health Center has been based on the conceptions that mentally ill patients have untapped potentialities for successful adjustment, and that optimal work in the field would require mobilization of patients, hospital and community resources in a comprehensive effort. The introduction of a new program requiring close collaboration of many services and disciplines has had a noticeable impact on hospital structure. Some role groups, especially psychiatrists and social workers, appear to be threatened by the new emphasis. Other role groups such as nurse, occupational and industrial therapists, have enjoyed a reinforcement of their status, and increased value seems to be attached to their functions. The experiences thus far with day hospital, halfway houses and social therapeutic clubs indicates that these methods have specific value in selected cases. Intensive investigation is underway to determine optimum relationship between the special facilities and hospital organization, degree of autonomy needed by patients, and factors determining success or failure of patients in ultizing different rehabilitative procedures.
Scintigraphic Evaluation of Patients With Suspected Pulmonary Thromboembolism
Authors: David A. Turner
Journal: JAMA (1987)

<h3>To the Editor.—</h3> In the June 19, 1987, issue of<i>JAMA</i>, the late Daniel R. Biello, MD, a pioneer in the development of criteria for the interpretation of pulmonary perfusion and ventilation scintigrams, once again has given us the benefit of his skill as a diagnostician and a teacher in an article reviewing the diagnosis of pulmonary thromboembolism.<sup>1</sup>He has placed special emphasis on the pivotal role of pulmonary scintigraphy in this task, presenting the latest version of the widely accepted algorithm for scintigraphic diagnosis of pulmonary thromboembolism that has come to bear his name (the Biello criteria) in the form of a table. One of the criteria for "high probability" of pulmonary thromboembolism listed in this and similar, previously published tables<sup>2-4</sup>should be refined to more fairly reflect the experience on which it is based and the way the criterion is actually applied in clinical practice. Dr
IMMUNOLOGICAL RELATIONSHIPS OF CELL CONSTITUENTS OF ENCAPSULATUS PNEUMONIÆ (FRIEDLÄNDER'S BACILLUS)
Authors: Louis A. Julianelle
Journal: The Journal of Experimental Medicine (1926)

1. The soluble specific substance of Friedländer's bacillus is non-antigenic when dissociated from the cell. It is different for each type and it is highly reactive in the corresponding anti-S serum. 2. The nucleoprotein is antigenic, induces the species or protein antibody which reacts with capsule-free cells and protein derived from all types. Antiprotein sera do not react with either the encapsulated cell or the polysaccharide derived from it, and they offer no protection against infection. 3. Anti-R and antiprotein sera are identical in their behavior. 4. The carbohydrate of Friedländer's bacillus is demonstrable in filtrates of actively growing cultures and in the blood and urine of infected animals. 5. The protein is demonstrable in filtrates of only old, disintegrating cultures.
EAU Guidelines for the Management of Urogenital Schistosomiasis
Authors: Karl-Horst Bichler, Ilya Savatovsky, Kurt G. Naber, Michael C. Bischop, Truls E. Bjerklund-Johansen, Henry Botto, Mete Cek, Magnus Grabe, Bernhard Lobel, Juan Palou Redorta, Peter Tenke
Journal: European Urology (2006)
Pesticide appliers, biocides, and birth defects in rural Minnesota.
Authors: V F Garry, D Schreinemachers, M E Harkins, J Griffith
Journal: Environmental Health Perspectives (1996)

Earlier studies by our group suggested the possibility that offspring of pesticide appliers might have increased risks of birth anomalies. To evaluate this hypothesis, 935 births to 34,772 state-licensed, private pesticide appliers in Minnesota occurring between 1989 and 1992 were linked to the Minnesota state birth registry containing 210,723 live births in this timeframe. The birth defect rate for all birth anomalies was significantly increased in children born to private appliers. Specific birth defect categories, circulatory/respiratory, urogenital, and musculoskeletal/integumental, showed significant increases. For the general population and for appliers, the birth anomaly rate differed by corp-growing region. Western Minnesota, a major wheat, sugar beet, and potato growing region, showed the highest rate of birth anomalies per/1000 live births: 30.0 for private appliers versus 26.9 for the general population of the same region. The lowest rates, 23.7/1000 for private appliers versus 18.3/1000 for the general population, occurred in noncorp regions. The highest frequency of use of chlorophenoxy herbicides and fungicides also occurred in western Minnesota. Births in the general population of western Minnesota showed a significant increase in birth anomalies in the same three birth anomaly categories as appliers and for central nervous system anomalies. This increase was most pronounced for infants conceived in the spring. The seasonal effect did not occur in other regions. The male/female sex ratio for the four birth anomaly categories of interest in areas of high phenoxy herbicide/fungicide use is 2.8 for appliers versus 1.5 for the general population of the same region (p = 0.05). In minimal use regions, this ratio is 2.1 for appliers versus 1.7 for the general population. The pattern of excess frequency of birth anomalies by pesticide use, season, and alteration of sex ratio suggests exposure-related effects in appliers and the general population of the crop-growing region of western Minnesota.
PSYCHIATRIC TREATMENT OF THE CALIFORNIA FELON
Authors: FRANKLIN H. ERNST, WILLIAM C. KEATING
Journal: American Journal of Psychiatry (1964)

The medical objective in the psychiatric treatment of the incarcerated felon is to cure him of his psychological and social tactics that eventuate in loss of his behavioral options and then loss of control over his social stimuli and responses; or, if you will, the relearning of how to use previously unpracticed social options for initiating or responding to conversations provides the inmate with a measure of social control previously not available to him. Two of the major advantages the so-called antisocial person gives up on cure are, 1. Playing "cops and robbers" with its attendant gratifications, and 2. The use of "go-directly-to-jail" to solve external or internal life stresses.
Recurrent Hypoglycemia Associated with Glutaric Aciduria Type II in an Adult
Authors: Geoffrey Dusheiko, Michael C. Kew, Barry I. Joffe, Jack R. Lewin, F. F. Path, Stephanos Mantagos, Kay Tanaka
Journal: New England Journal of Medicine (1979)

Repeated episodes of hypoglycemia accompanied by elevated serum concentrations of free fatty acid without ketosis, fatty infiltration of the liver, hepatic dysfunction, and proximal myopathy in a 19-year-old woman, prompted us to analyze her urine for organic acids. Greatly increased quantities of glutaric acid, ethylmalonic acid, dicarboxylic acids with six to 10 carbons, and isovalerylglycine were consistently found in her urine. The ability of cultured skin fibroblasts from the patient to oxidize [1(-14)C]butyrate and [2(-14)C]lysine was reduced. These urinary and in vitro findings indicated defective activity of several acyl coenzyme A dehydrogenases, including glutaryl, isovaleryl, and butyryl coenzyme A dehydrogenases -- establishing a diagnosis of glutaric aciduria Type II. Carnitine concentrations in the skeletal muscle and liver were moderately reduced, but carnitine deficiency was considered a secondary biochemical abnormality. Although glutaric aciduria Type II has previously been described only in a neonate, the disease must be considered in the differential diagnosis of hypoglycemia in adults.
A Behavioral Treatment of Alcoholic Methadone Patients
Authors: IRA A. LIEBSON
Journal: Annals of Internal Medicine (1978)

Alcoholism is a frequent complication of methadone treatment and is one of the few behaviors found to correlate with methadone treatment failure. To eliminate drinking among severely alcoholic patients, we tested the efficacy of incorporating methadone into a behavioral contingency to reinforce disulfiram ingestion. Methadone was dispensed to alcoholic narcotic addicts contingent upon their ingesting disulfiram, and as a control patients were urged to take disulfiram but received methadone regardless of whether they took disulfiram. The results indicated that the reinforced disulfiram treatment was highly successful in controlling alcoholism. In addition, nonstatistically significant trends suggested that the reinforced disulfiram treatment resulted in a superior adjustment, as reflected in arrest rate, unemployment, and illicit drug use. There appeared to be no significant physiologic or behavioral adverse effects.
Intestinal Disaccharidase Activity in Rosacea
Authors: E. Paton, E. Murray, W. C. Watson
Journal: BMJ (1966)

Symptoms of intestinal discomfort attributed to carbohydrate intolerance (Kendall, 1926) have long been recognized as a feature of rosacea (Eastwood, 1928), but attempts to alleviate them and improve the facial flushing with a low-carbohydrate diet have been only partially successful (Stokes and Beerman, 1932).
Early Spontaneous Slippage of Rubber Bands with Fatal Bleeding: a Rare Complication of Endoscopic Variceal Ligation
Authors: I. Mishin, A. Dolghii
Journal: Endoscopy (2005)

The risk of fatal massive bleeding after successful endoscopic variceal ligation (EVL) is very low [1]. To date, only a few reports have been published in the English-language literature on life-threatening bleeding due to ulceration following variceal banding [2] [3] [4]. The present report describes an additional case of this fatal complication resulting from early spontaneous slippage of rubber bands.
The 'Muckle–Wells' syndrome
Authors: T.J. MUCKLE
Journal: British Journal of Dermatology (1979)

Journal Article The 'Muckle–Wells' syndrome Get access T.J. MUCKLE T.J. MUCKLE Chedoke Hospitals, Sanatorium Road, Hamilton, Ontario, Canada Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 100, Issue 1, 1 January 1979, Pages 87–92, https://doi.org/10.1111/j.1365-2133.1979.tb03572.x Published: 01 January 1979
TCT-54 Additive Prognostic Value Of The Global Registry Of Acute Coronary Events Score Over Other Risk Scores For In-Hospital Outcome Prediction In Patients Presenting With ST-Elevation Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention
Authors: Lorenzo Azzalini, Razi Khan, Malek Al-Hawwas, Raja Hatem, Annik Fortier, Philippe L. L'Allier, Hung Q. Ly
Journal: Journal of the American College of Cardiology (2014)
Steady-State Kinetics of the Quinolone Derivatives Ofloxacin, Enoxacin, Ciprofloxacin and Pefloxacin during Maintenance Treatment with Theophylline
Authors: W. J.A. Wijnands, T. B. Vree, A. M. Baars, C. L.A. van Herwaarden
Journal: Drugs (1987)
Nombre et caractéristiques des cancers colorectaux (CCR) d'intervalle après test Hémoccult® négatif. Part du dépistage dans les CCR diagnostiqués dans la tranche d'âge 50–74 ans
Authors: C Jézéquel, S Manfredi, G Mallard, C Piette, G Durand, JF Bretagne
Journal: Endoscopy (2008)

But: La sensibilité imparfaite du test Hémoccult® expose au risque de CCR d'intervalle les sujets ayant fait le dépistage, mais nous ne disposons que de peu d'informations en population sur ces CCR. Nous ne savons pas non plus la part représentée par le dépistage dans le diagnostic des CCR à l'échelle d'un département. Le but de l'étude a été d'étudier le nombre et les caractéristiques des CCR d'intervalle comparativement aux CCR dépistés et de définir la part représentée par le dépistage dans le diagnostic des CCR.
A "cracking" complication of hemiarthroplasty of the hip.
Authors: I J Brenkel, M Pearse, P J Gregg
Journal: BMJ (1986)

In summary, the ancient Greek meaning of the word was to describe a state of exhaustion, exposure, and hunger, the hunger occurring naturally.In mediaeval English the word came tosignify an illogical mental disorder characterised by an extreme, perpetual, animal type ofhunger, which seems to approximate its current use by the psychiatric community.In a non- medical, general sense, however, it may be used to express extreme voraciousness.
Right Ventricular Hypertrophy
Authors: ISOM C. WALKER, ROBERT A. HELM, RALPH C. SCOTT
Journal: Circulation (1955)

The electrocardiograms of 22 cases showing isolated right ventricular hypertrophy at autopsy were examined for changes suggestive of right ventricular hypertrophy. Only 5 of 22 cases fulfilled at least one of the criteria of Sokolow and Lyon and only three could be diagnosed as having right ventricular hypertrophy by the criteria of Myers, Klein and Stofer. Factors contributing to the development of electrocardiographic changes of right ventricular hypertrophy are discussed.
Esophagopericardial Fistula With Survival
Authors: Glen E. Miller
Journal: JAMA (1974)

<h3>To the Editor.—</h3> Causes of pneumopericardium, a rare intrathoracic lesion, were classified by Shackelford<sup>1</sup>and by Meyer.<sup>2</sup>Stephenson et al<sup>3</sup>listed 13 cases, including his own cases, all with fatal outcome. Frey<sup>4</sup>described a fatal case due to extension of an ulcer in a hiatus hernia. The first reported survivor with this entity was a 6-year-old girl.<sup>5</sup>She had a perforated peptic ulcer of the esophagus with probable fistula formation to the pericardium. Romhilt<sup>6</sup>described a fatal case of perforation of an ulcer through the intrathoracic portion of the stomach, and this report describes survival of surgical repair of an open esophagopericardial fistula. <h3>Report of a Case.—</h3> A 72-year-old man had undergone surgical repair of a hiatus hernia four years previously. At that time, the diameter of the distal esophagus was found to be less than 1 cm, and surgical release of the stricture was
A PLEA FOR A MORE LIVING PATHOLOGY
Authors: H. Sainsbury
Journal: BMJ (1909)

MORE LIVING PATHOLOGY. [OCT. 2, I909. in our exhibition, the one illustrating Servetus, the other Ulrich von Hutten.Valuable as they are from the stand- point of the professional bibliographer, this is nothing to the interest awakened in the men themselves, in their aspirations, their labour, and their tragic fates.For the amateur this personal note clothes the dry bones of bibliography and makes them live.And my other principle is this: a student of the history of medicine, I look out for books which have left their impress on it in some special way.If one is particular to examine carefully into the claims of a book before admitting it to the select company
A SIMPLE PORTABLE REFRIGERATING BOX AND ITS USE AS A TEMPORARY INCUBATOR IN MILITARY WORK
Authors: S. Delepine
Journal: BMJ (1916)

A PORTABLE REFRIGERATING BOX.[MAY 20, I916 was connected to one pole of the galvanometer.The second pole was connected to a small silver button 2 mm. in diameter mounted in a vulcanite handle which could be Drought into contact with any part it miglht be desired to test.With both poles in contact witlh tlle patient's body and the circuit key closed a deflection was obtained on the galvanometer scale which could be read off in millimetres.The first case was that of a soldier under my care in
Effect of flosulide, a selective cyclooxygenase 2 inhibitor, on passive Heymann nephritis in the rat
Authors: Cornelia Blume, Gunhild Heise, Anja Mühlfeld, Dieter Bach, Karsten Schrör, Claus Dieter Gerhardz, Bernd Grabensee, Peter Heering
Journal: Kidney International (1999)
Controlled Trials for Neonatal Meningitis
Authors: Chris J. J. Mulder
Journal: JAMA (1985)

<h3>To the Editor.—</h3> Dr McCracken and co-workers<sup>1</sup>compared two therapeutic regimens in 63 children with "neonatal" gram-negative meningitis. Fifteen of these children were older than 30 days. In group A, 60% of the cases were caused by<i>Escherichia coli</i>, and the age at onset of illness was 29 ± 19 days and in group B, only 45% of the cases were caused by<i>E coli</i>, and the age at onset of illness was only 19 ± 18 days. We demonstrated that<i>E coli</i>neonatal meningitis has a lower case-fatality rate than non-<i>E coli</i>gramnegative meningitis,<sup>2,3</sup>and that the case-fatality rate in the younger age group (0 to 6 days of age) was higher than in the older age group (7 to 27 days of age).<sup>4,5</sup> The results of McCracken et al must be interpreted in light of these facts. Furthermore, the interpretation of their results is difficult
Cecil-Loeb Textbook of Medicine.
Authors: Russell L. Cecil, Robert Frederick Loeb, Paul B. Beeson, Walsh McDermott
Journal: Annals of Internal Medicine (1971)

To attempt a comprehensive review of the 11th edition of the Cecil-Loeb Textbook of Medicine, newly edited by Beeson and McDermott, is comparable with trying to do the British Museum in an afternoon\p=m-\itsimply cannot be done. A book produced by 173 different authors on 750 subjects probably should be reviewed by a committee; however, since individual practitioners and students will be using this volume,
Pertussis Vaccination and Asthma: Is There a Link?
Authors: Michel R. Odent
Journal: JAMA (1994)

To the Editor.  —From the article by Drs Ellis and Douglas,1it appears that where the overall population of infants is concerned, the use of acellular pertussis vaccine might be one of the main changes to be expected in the near future.  This gives us an opportunity to report unexpected findings apparently linked with the use of the current inactivated bacterial vaccine.  We were studying criteria of health in 448 children and adolescents. All of them received only breast milk during the first 6 months, and in particular on the first day following birth. All of them were weaned after 1 year of age and were older than 4 years at the time the parents responded. The mean age was 7.87 years.  To the question Has your child ever been diagnosed as asthmatic? there were 30 positive answers (6.72%). The surprise came when we classified the questionnaire according to
Knee and hip replacements have extensive non-medical benefits, finds study
Authors: B. Roehr
Journal: BMJ (2013)

Working age adults in the United States who had a total knee replacement were 20% more likely to become employed, and their average annual income rose by $4300 (£2800; €3340), a study has found. They also had six fewer days off work with sickness than those who did not have replacement surgery, and they reduced their reliance on disability benefits. Similar benefits were seen with hip replacements.

The analysis drew primarily on data from 185 829 adults not living in institutions who participated in the Centers …
Hugh Williamson: Physician, Patriot, and Founding Father
Authors: Joseph B. VanderVeer
Journal: JAMA (2011)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Purchase of Read codes heavily criticised by National Audit Office
Authors: D. Carnall
Journal: BMJ (1998)

There were “serious problems” with the purchase of the Read codes by the NHS Executive, and “substantial weaknesses” in the subsequent management arrangements, according to a report published by the National Audit Office last week.

The development of the codes is an integral part of the NHS's plans to link hospitals and general practices together on computer networks. The report said that the NHS Executive created a situation with potential conflicts of interest when it agreed both to employ Dr James Read, the inventor of the codes, as the director of the new Centre for Coding and Classification, and to allow a company wholly owned by him, Computer Aided Medical Systems (CAMS), to have exclusive rights to the marketing of the codes.

The auditor …
Leucine. A possible regulator of protein turnover in muscle.
Authors: M G Buse, S S Reid
Journal: Journal of Clinical Investigation (1975)

Incorporation of radiolabeled precursors into muscle proteins was studied in isolated rat hemidiaphragms. A mixture of three branched-chain amino acids (0.3 mM each) added to media containing glucose stimulated the incorporation of [14C]lysine into proteins. When tested separately, valine was ineffective, isoleucine was inhibitory, but 0.5 mM leucine increased the specific activity of muscle proteins during incubation with [14C]lysine or [14C]acetate in hemidiaphragms from fed or fasted rats incubated with or without insulin. Preincubation with 0.5 mM leucine increased the specific activity of muscle proteins during a subsequent 30- or 60-min incubation with [14C]lysine or [14C]pyruvate without leucine. Preincubation with other amino acids (glutamate, histidine, methionine, phenylalanine, or tryptophan) did not exert this effect. When hemidiaphragms were incubated with a mixture of amino acids at concentrations found in rat serum and a [14C]lysine tracer, the specific activity of muscle proteins increased when leucine in the medium was raised from 0.1 to 0.5 mM. Experiments with actinomycin D and cycloheximide suggested that neither RNA synthesis nor protein synthesis are required for the initiation of the leucine effect. Leucine was not effective when added after 1 h preincubation without leucine. The concentration of lysine in the tissue water of diaphragms decreased during incubation with 0.5 mM leucine in the presence or absence of cycloheximide, suggesting that leucine inhibited protein degradation. During incubation with [3h]tyrosine (0.35 mM) the addition of 0.5 mM leucine increased the specific activity of muscle proteins, while the specific activity of intracellular tyrosine remained constant and its concentration decreased, suggesting that leucine also promoted protein synthesis. The concentration of leucine in muscle cells or a compartment thereof may play a role in regulating the turnover of muscle proteins and influence the transition to negative nitrogen balance during fasting, uncontrolled diabetes, and the posttraumatic state. Leucine may play a pivotal role in the protein-sparing effect of amino aicds.