Budesonide and Psychic Side Effects
Authors: R.H.B. Meyboom, N. de Graaf-Breederveld
Journal: Annals of Internal Medicine (1988)

Letters and Corrections15 October 1988Budesonide and Psychic Side EffectsR.H.B. Meyboom, N. de Graaf-BreederveldR.H.B. MeyboomSearch for more papers by this author, N. de Graaf-BreederveldSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-109-8-683_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editor: The systemic use of corticosteroids is limited by various serious side effects, including psychic disturbances, such as euphoria, depression, and manic or paranoid states (1). The advantage of administering corticosteroids by the inhalation route is that patients with asthma can benefit from corticosteroid treatment with less systemic side effects (1, 2). We report two cases of psychic side effects in patients receiving treatment with corticosteroid budesonide (Pulmicort) by the inhalation route.A 39-year-old man without a history of psychic disturbances had attacks of bronchogenic dyspnea. Treatment with inhaled budesonide, two puffs (0.2 mg) two times daily, was...References1. Von Eickstedt K. Corticotropins and corticosteroids. In: Dukes MNG, ed. Meyler's Side Effects of Drugs, 10th ed. Amsterdam: Elsevier Science Publishers; 1984:727-43. Google Scholar2. Clark T, ed. Steroids in Asthma: A Reappraisal in the Light of Inhalation Therapy. Auckland: Adis Press; 1983. Google Scholar3. Lewis L and Cochrane G. Psychosis in a child inhaling budesonide. Lancet. 1983;2:634. CrossrefMedlineGoogle Scholar4. Clissold S and Heel R. Budesonide, a primary review of its pharmacodynamic properties and therapeutic efficacy in asthma and rhinitis. Drugs. 1984;28:485-518. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: R.H.B. Meyboom; N. de Graaf-Breederveld PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byInhalation of nebulized omega-3 fatty acids mitigate LPS-induced acute lung inflammation in rats: Implications for treatment of COPD and COVID-19Are BDNF and glucocorticoid activities calibrated?Antiglucocorticoids in psychiatryIntranasally administered corticosteroids and neuropsychiatric disturbances: a review of the International Pharmacovigilance Programme of the World Health OrganizationReported adverse drug reactions during the use of inhaled steroids in children with asthma in the NetherlandsNeuropsychologic changes and inhaled corticosteroidsAsthma Severity, Psychiatric Morbidity, and Quality of Life: Correlation with Inhaled Corticosteroid DoseCorticosteroids in Chronic Obstructive Pulmonary DiseaseInhaled and nasal corticosteroids: safety aspects*Corticosteroid-Induced Adverse Psychiatric EffectsSAFETY AND EFFICACY OF INHALED CORTICOSTEROIDS IN CHILDRENLearning Disorders Associated with Asthma and AllergiesPsychoactive Effects of Medical DrugsNeuropsychological and Behavioral Changes in Asthmatic Children Treated With Beclomethasone Dipropionate Versus TheophyllineMEDICATION-INDUCED PSYCHOTIC REACTIONSteroid therapy in obstructive airway diseasesAdverse Effects of Corticosteroid Therapy for COPDCorticosteroids in Pediatric AsthmaInhaled Corticosteroids: Benefits and RisksAdverse effects of inhaled corticosteroidsPsychologic Side Effects of Therapy with CorticosteroidsPsychoactive Effects of Medical DrugsClinical pharmacology of corticosteroids in bronchial asthmaSpontaneous Monitoring of Adverse Reactions to Drugs, Procedures, and Experiences in the NetherlandsCorticosteroids and corticotrophins 15 October 1988Volume 109, Issue 8 Page: 683-683 Keywords Asthma Bipolar disorder Dyspnea Inhalation Patients ePublished: 1 December 2008 Issue Published: 15 October 1988 PDF downloadLoading ...