tbuckley/cabot-search huggingface dataset:
THE TREATMENT OF HYDROPHOBIA, HISTORICALLY AND PRACTICALLY CONSIDERED.
Authors: CHARLES W. DULLES
Journal: JAMA (1884)

The history of medicine can be traced back, more or less obscurely, to a period about 1200 years before the Christian era to whatever real or fabled healer may have been the foundation of the myth of Aesculapius, yet Aristotle, who lived from 38410 322 B. C, is the first writer, whose works are extant, by whom we have distinct mention of the subject of hydrophobia. His reference to it has given rise to much discussion, because it does not accord with what is commonly believed about it, but there can be no doubt that he spoke of what is now known by this name. His expression is: "Dogs are subject to three diseases. These are called lyssa, cynanche and podagra. Of these lyssa causes mania, andwhatever is bitten (δταυ ϛσκη) all those bitten go mad except man. (λυττώσιν άπαντα τα δηχθέατα πληα άαϑςωπον). This disease seizes on dogs and
The Risk for Systemic Vascular Diseases and Mortals Yin Patents with Central Retinal Vein Occlusion
Authors: Michael J. Elman, Amita Kaur Bhatt, Patricia M. Quinlan, Cheryl Enger
Journal: Ophthalmology (1990)

In this cross-sectional study, the authors evaluated 197 patients diagnosed with central retinal vein occlusion (CRVO) at the Wilmer Ophthalmological Institute between 1980 and 1985 to determine the risk of systemic disease and mortality. Complete follow-up information for mortality was obtained in 191 (97%). National Health Interview Survey (NHIS) patients and Wilmer cataract patients formed two comparison groups. The prevalence of hypertension was significantly elevated in the CRVO cases when compared with both comparison groups (P less than 0.03, 0.005). The prevalence of diabetes mellitus was increased in CRVO cases in comparison with the NHIS group (P less than 0.005). The prevalence of cerebrovascular or cardiovascular disease was the same for all three groups, as was overall mortality. Mortality was not increased in CRVO cases as compared with United States mortality rates.
Reviews and Notes: Education: Training Physicians: The Case of Internal Medicine
Authors: Gerald E. Thomson
Journal: Annals of Internal Medicine (1995)

Literature of Medicine15 September 1995Reviews and Notes: Education: Training Physicians: The Case of Internal MedicineGerald E. Thomson, MDGerald E. Thomson, MDCollege of Physicians and Surgeons, Columbia University, New York, NY 10032-Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-123-6-199509150-00038 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Training Physicians: The Case of Internal Medicine. CH Kohrman, R Andersen, and MM Clements. 450 pages. San Francisco: Jossey-Bass; 1994. $48.95. ISBN 0-78790-038-9. Order phone 415-433-1767.The postgraduate education of physicians has been shaped by various forces other than the need to train appropriate numbers of physicians in specialties. The pivotal role of internal medicine in the physician work force and health system of the United States, as well as the complexity of internal medicine, makes this field an important one for study and inference.The authors of this book have drawn on 17 years of demographic results from the ... Author, Article, and Disclosure InformationAffiliations: College of Physicians and Surgeons, Columbia University, New York, NY 10032- PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 15 September 1995Volume 123, Issue 6Page: 480KeywordsCritical careFallsGeriatricsGraduate medical educationPublic policyResidencySub-specialty care ePublished: 15 August 2000 Issue Published: 15 September 1995 Copyright & PermissionsCopyright © 1995 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Regional Enteritis Associated with Enterovirus in a Patient with X-Linked Agammaglobulinemia
Authors: Christophe Cellier, Sophie Foray, Olivier Hermine
Journal: New England Journal of Medicine (2000)

To the Editor: Gryfe et al. (Jan.13 issue) 1 report that microsatellite instability in colorectal cancer is independently predictive of a favorable outcome.We have some concern about this conclusion, since the tumors with microsatellite instability were more frequently localized (59 percent, vs. 38 percent of those with microsatellite stability) and since the 10-year survival at each Dukes' stage did not differ significantly between patients with microsatellite instability and those with microsatellite stability (Fig. 2B,2C,2D, and 2E in the article).The authors state that in a multivariate analysis, microsatellite status was found to be "significantly and independently" associated with survival.In our opinion, however, we still need clear evidence in a univariate analysis of a survival advantage at each Dukes' stage.
Bronchopulmonary infection due to Branhamella catarrhalis: 11 cases assessed by transtracheal puncture.
Authors: G Ninane, J Joly, M Kraytman
Journal: BMJ (1978)

Transtracheal punctures were performed in 193 miners of anthracosilicotic coal who presented with an acute exacerbation of chronic bronchitis. The transtracheal aspirates were bacteriologically positive in 104 patients. Branhamella catarrhalis was isolated in 15 patients; 10 of these responded to chemotherapy, as shown by the resolution of all symptoms and the disappearance of the organism on a repeat transtracheal puncture performed 48 hours after the end of treatment. One ampicillin-treated patient, whose bronchial secretions yielded a beta-lactamase-producing B catarrhalis, showed no improvement. But subsequent treatment with cefuroxime was followed by clinical and bacteriological recovery. B catarrhalis probably acted as an opportunistic respiratory pathogen in these patients, who were probably compromised hosts in view of their clinical history. B catarrhalis normally responds to the penicillins commonly used for respiratory infections, but if treatment fails a transtracheal puncture is essential to identify the strain and determine an appropriate antibiotic.
Artistic Response to Genomic Research Shown
Authors: Lynne Lamberg
Journal: JAMA (2002)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Immunologic Mechanisms in Multiple Sclerosis
Authors: Robert L. Owen
Journal: JAMA (1980)

A 29-year-old man with quiescent multiple sclerosis had hemiparesis during the prodrome of serologically confirmed type A hepatitis. After neurological symptoms and acute hepatitis had abated, hemiparesis again developed when skin tests were applied. While he was receiving prednisone, skin test inflammation and neurological signs cleared. One year later, lymphocyte stimulation, which had been noticeably elevated during his exacerbations, returned to low normal. Both hepatitis A and skin test antigens produced immunostimulation that resulted in exacerbation of multiple sclerosis. (<i>JAMA</i>244:2307-2309, 1980)
Long-Term Use of a Left Ventricular Assist Device for End-Stage Heart Failure
Authors: Eric A. Rose, Annetine C. Gelijns, Alan J. Moskowitz, Daniel F. Heitjan, Lynne W. Stevenson, Walter Dembitsky, James W. Long, Deborah D. Ascheim, Anita R. Tierney, Ronald G. Levitan, John T. Watson, Nuala S. Ronan, Peter A. Shapiro, Ronald M. Lazar, Leslie W. Miller, Lopa Gupta, O. Howard Frazier, Patrice Desvigne-Nickens, Mehmet C. Oz, Victor L. Poirier, Paul Meier
Journal: New England Journal of Medicine (2001)

Implantable left ventricular assist devices have benefited patients with end-stage heart failure as a bridge to cardiac transplantation, but their long-term use for the purpose of enhancing survival and the quality of life has not been evaluated.
Treatment of Chronic Uremia Using Isolated Intestinal Loops.
Authors: James E. Clark
Journal: Annals of Internal Medicine (1965)

s1 May 1965Treatment of Chronic Uremia Using Isolated Intestinal Loops.James E. Clark, M.D., F.A.C.P., Herbert E. Cohn, M.D., John Y. Templeton III, M.D.James E. Clark, M.D., F.A.C.P.Search for more papers by this author, Herbert E. Cohn, M.D.Search for more papers by this author, John Y. Templeton III, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-62-5-1091_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSegments of ileum or jejunum were isolated from the remaining bowel and one or both ends exteriorized in 19 chronically uremic patients. The etiology of their uremia varied widely, and all patients but one had endogenous creatinine chromogen clearances of less than 4 ml/min. Sixteen patients had undergone previous peritoneal or hemodialysis. There were no operative deaths. Two patients were totally anuric, and one of these was able to be discharged to dialyze herself at home. Of eight other patients who were able to be discharged and dialyze themselves at home, the longest follow up has been 21 months. Urea... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Philadelphia, Pennsylvania PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySynthesis of Gamma-Alumina Nanoparticles by Freeze Drying 1 May 1965Volume 62, Issue 5Page: 1091-1091KeywordsCreatinineEtiologyIleumJejunumUrea ePublished: 1 December 2008 Issue Published: 1 May 1965 PDF downloadLoading ...
Huygens' Principle: A case against optimality
Authors: Hans-Martin Gaertner
Journal: Behavioral and Brain Sciences (2003)

I will present evidence that nature does not optimize in the sense of Fermat's principle of least time, contrary to what Schoemaker's unintentionally ambiguous exposition might suggest. First, Huygens' principle, an alternative nonteleological account of Snell's law, is outlined. Second, I confront Fermat's principle with a substantive conceptual problem.
Review: Application of heat or hot water reduces pain from jellyfish stings
Authors: Nicholas A. Buckley, Geoffrey K. Isbister
Journal: Annals of Internal Medicine (2012)

ACP Journal Club18 December 2012Review: Application of heat or hot water reduces pain from jellyfish stingsNicholas A. Buckley, MD, Geoffrey K. Isbister, MDNicholas A. Buckley, MDUniversity of New South Wales, Sydney, New South Wales, Australia (N.A.B.), Geoffrey K. Isbister, MDUniversity of Newcastle, Newcastle, New South Wales, Australia (G.K.I.)Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-157-12-201212180-02012 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Source CitationWard NT, Darracq MA, Tomaszewski C, Clark RF. Evidence-based treatment of jellyfish stings in North America and Hawaii. Ann Emerg Med. 2012;60:399-414. https://pubmed.ncbi.nlm.nih.gov/22677532Clinical Impact RatingsEmergency Med: Reference1 Birsa LM, Verity PG, Lee RF. Evaluation of the effects of various chemicals on discharge of and pain caused by jellyfish nematocysts. Comp Biochem Physiol C Toxicol Pharmacol. 2010;151:426-30. [PMID: 20116454] Google Scholar Author, Article, and Disclosure InformationAuthors: Nicholas A. Buckley, MD; Geoffrey K. Isbister, MDAffiliations: University of New South Wales, Sydney, New South Wales, Australia (N.A.B.)University of Newcastle, Newcastle, New South Wales, Australia (G.K.I.)This article was published at Annals.org on 4 December 2012. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byRaising Awareness on the Clinical and Forensic Aspects of Jellyfish Stings: A Worldwide Increasing Threat 18 December 2012Volume 157, Issue 12Page: JC6-12KeywordsArmed forcesClinical trialsErythemaSulfatesVenoms ePublished: 18 December 2012 Issue Published: 18 December 2012 Copyright & PermissionsCopyright © 2012 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
European Medicines Agency gives favourable ruling on NSAIDs
Authors: Rory Watson
Journal: BMJ (2006)

The London based European Medicines Agency, after a month long investigation, has decided that the benefit-risk balance of non-selective non-steroidal antiinflammatory drugs (NSAIDs) remains favourable.

The review, which was requested in September by France's national medicines agency, takes account of the publication of new data and analyses on thrombotic cardiovascular safety and develops initial recommendations made …
Effects of Nydrane on Epilepsy in Mental Defectives
Authors: D. S. Sharpe, G. Dutton, J. R. Mirrey
Journal: BMJ (1958)

THIOPENTONE AND DYSTROPHIA MYOTONICA routine taking of family histories should not be omitted.Bourke and Zuck point out the significance of the high incidence of cataract in these patients and the modern trend towards general anaesthesia for ophthalmic surgery.Particular care should be taken, when thiopentone is used for dental extractions in the chair, to be on the look-out for respiratory depression after unusually small doses.A means of ventilating the patient should always be at hand.The possibility of meeting a case of dystrophia myotonica in these circumstances, among other reasons, should discourage any but the most experienced from administering thio- pentone in the dental chair.In the United States thiopentone is more widely used as a 2.5% solution than in this country.There is much to recommend this practice and little, if anything, to condemn it.In known or suspect cases of dystrophia myotonica a dilute solution, not stronger than 2.5%, should be used and a dose of 100 mg. has been recommended: respiratory depression seems to be inevitable, and with doses smaller than 100 mg.there is the chance that loss of consciousness may not result.Apparatus for the artificial inflation of the lungs must be at hand, and Dundee recommends inflation with nitrous oxide and oxygen rather than oxygen alone, because of the possibility of a return to consciousness whilst apnoea persists.If it is desired to intubate the trachea, this will usually be found possible without the use of a relaxant.I am indebted to Dr. C. Langton Hewer for his advice, and to
Influence of mutations in hepatitis B virus surface protein on viral antigenicity and phenotype in occult HBV strains from blood donors
Authors: Cheng-Hao Huang, Quan Yuan, Pei-Jer Chen, Ya-Li Zhang, Chang-Rong Chen, Qing-Bing Zheng, Shiou-Hwei Yeh, Hai Yu, Yu Xue, Yi-Xin Chen, Ping-Guo Liu, Sheng-Xiang Ge, Jun Zhang, Ning-Shao Xia
Journal: Journal of Hepatology (2012)
Abstract 2680: Characterization of cultured circulating melanoma cells for individualized therapy
Authors: Katarina Kolostova, E. Hroncova, M. Liberko, Robert M. Hoffman, M. Arenbergerova, L. Rossmeislová, M. Romzova, Vladimir Bobek
Journal: Cancer Research (2012)

Abstract In the presented study circulating melanoma cells (CMSs) have been isolated from a B16 mouse melanoma model and from melanoma patients. Culture of CMCs has enabled us to perform drug sensitivity testing on them. The main hypothesis was to compare drug sensitivity of primary tumor cells grown in culture with the sensitivity of CMCs grown in vitro after capture. B16 murine melanoma was implanted i.p. in mice. Fourteen days after peritoneal injection, mice were sacrificed and blood obtained by cardiac puncture for CMCs-capture. The CMCs were captured either by immunomagnetic separation (Adnagen, AdnaTest Melanoma Select™, Germany) and/or blood added to culture flask containing growing medium. Sensitivity to cisplatin (CDDP) was tested with the MTT-assay at different concentrations. Primary melanoma and disseminated tumor cells (DTCs) were also cultured and tested. The DTCs were isolated from peritoneal washing (ascites like cells), lymph nodes and peritoneal fat tissue. CMCs and DTCs were found less sensitive to CDDP than primary melanoma cells. The ability to capture and culture CTCs enabled these studies which can be used for individualized therapy design. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 103rd Annual Meeting of the American Association for Cancer Research; 2012 Mar 31-Apr 4; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2012;72(8 Suppl):Abstract nr 2680. doi:1538-7445.AM2012-2680
Lettuce-Craving and Iron Deficiency
Authors: JAY W. MARKS
Journal: Annals of Internal Medicine (1973)

Comments1 October 1973Lettuce-Craving and Iron DeficiencyJAY W. MARKS, M.D.JAY W. MARKS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-79-4-612 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: I was interested in the letter from Drs. Chandra and Rosner (Ann Intern Med78:973-974, 1973) about olives-craving in iron deficiency anemia. I wish to add my own experience with a patient I saw recently.A 44-year-old menstruating woman had mild symptoms of dyspepsia. Initially, her hemoglobin was 13 g/100 ml, but during a 2-month period it progressively fell to 9.7 g/100 ml. At that time the red cells were slightly microcytic and hypochromic, and her serum iron level was low, with the iron-binding capacity borderline-high. Bone marrow iron was absent. Stool specimens for occult blood were... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: JAY W. MARKS, M.D.Affiliations: Cedars-Sinai Medical Center Los Angeles, California PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 October 1973Volume 79, Issue 4Page: 612-612KeywordsBloodBone marrowCellsHemoglobinIron deficiency ePublished: 13 March 2020 Issue Published: 1 October 1973 PDF downloadLoading ...
Optimizing Pemetrexed-Gemcitabine Combination in Patients with Advanced Non-small Cell Lung Cancer: A Pharmacogenetic Approach
Authors: Tommaso M. De Pas, Francesca Toffalorio, Elisa Giovannetti, Davide Radice, Francesca Russo, Ilaria Angeli, Giulia Calamai, Gianluca Spitaleri, Chiara Catania, Cristina Noberasco, Alessandra Milani, Giuseppe Pelosi, Romano Danesi, Filippo De Braud
Journal: Journal of Thoracic Oncology (2011)
Transcription factor EGR1 directs tendon differentiation and promotes tendon repair
Authors: Marie-Justine Guerquin, Benjamin Charvet, Geoffroy Nourissat, Emmanuelle Havis, Olivier Ronsin, Marie-Ange Bonnin, Mathilde Ruggiu, Isabel Olivera-Martinez, Nicolas Robert, Yinhui Lu, Karl E. Kadler, Tristan Baumberger, Levon Doursounian, Francis Berenbaum, Delphine Duprez
Journal: Journal of Clinical Investigation (2013)

Tendon formation and repair rely on specific combinations of transcription factors, growth factors, and mechanical parameters that regulate the production and spatial organization of type I collagen. Here, we investigated the function of the zinc finger transcription factor EGR1 in tendon formation, healing, and repair using rodent animal models and mesenchymal stem cells (MSCs). Adult tendons of Egr1-/- mice displayed a deficiency in the expression of tendon genes, including Scx, Col1a1, and Col1a2, and were mechanically weaker compared with their WT littermates. EGR1 was recruited to the Col1a1 and Col2a1 promoters in postnatal mouse tendons in vivo. Egr1 was required for the normal gene response following tendon injury in a mouse model of Achilles tendon healing. Forced Egr1 expression programmed MSCs toward the tendon lineage and promoted the formation of in vitro-engineered tendons from MSCs. The application of EGR1-producing MSCs increased the formation of tendon-like tissues in a rat model of Achilles tendon injury. We provide evidence that the ability of EGR1 to promote tendon differentiation is partially mediated by TGF-β2. This study demonstrates EGR1 involvement in adult tendon formation, healing, and repair and identifies Egr1 as a putative target in tendon repair strategies.
709-3 Efficacy and Safety of Palmaz-Schatz Stent in Elderly (≥ 75 Years Old) Patients: Early and Follow-up Results
Authors: Hiroyoshi Yokoi, Takeshi Kimura, Yoshihiro Sawada, Hideyuki Nosaka, Masakiyo Nobuyoshi
Journal: Journal of the American College of Cardiology (1995)
TCT-307 Frequency and Impact of Failure to Cannulate the Left Internal Mammary Artery: Results of the SLIME1 (Selective Left Internal Mammary Evaluation) Trial
Authors: Evin Yucel, Brian J. McEniry, Deepak Thatai, Brian J. Corbett, Zoltan Turi
Journal: Journal of the American College of Cardiology (2013)
Control of Maturity-Onset Diabetes by Monitoring Fasting Blood Glucose and Body Weight
Authors: S Howe-Davies, R W Simpson, R C Turner
Journal: Diabetes Care (1980)

The feasibility of reducing the fasting blood glucose (FBG) level to &amp;lt;6 mmol/L has been studied in all 84 maturity-onset diabetic (MOD) patients in three general practices. Only 35 (48%) were initially “well controlled” by this criterion, although 72 (86%) had no postprandial glycosuria. Seventy-one patients were monitored for 6 mo. With additional oral hypoglycemic therapy where necessary, the number of “well controlled” increased from 29 (41%) to 54 (76%), associated with a significant decrease in the hemoglobin A1. The patients were subsequently assessed at two 3-monthly intervals, and a fasting plasma glucose &amp;gt;4 and &amp;lt;6 mmol/L was usually maintained. All but two patients with a fasting glucose level &amp;lt; 6 mmol/L had fasting triglyceride concentrations &amp;lt; 2 mmol/L. The fasting blood glucose can be assayed in general practice with glucose-oxidase strips, and control by this means is simpler, cheaper, and more effective than regular urine glucose monitoring.
Isolation of Measles Virus at Autopsy in Cases of Giant-Cell Pneumonia without Rash
Authors: John F. Enders, Kevin McCarthy, Anna Mitus, William J. Cheatham
Journal: New England Journal of Medicine (1959)

GIANT-cell pneumonia, often referred to as Hecht's giant-cell pneumonia, is an interstitial pneumonitis that has so far been observed only in children. It is characterized by the presence of multinuclear giant cells with intranuclear and intracyto-plasmic inclusion bodies.1 2 3 4 5 6 7 8 9 Additional pathological features are a preponderance of mononuclear cells in the infiltrate, squamous metaplasia of the bronchial and bronchiolar epithelium, proliferation of alveolar lining cells and the occurrence in occasional cases of giant cells in organs other than the lungs. The changes characteristically found in the affected lung are illustrated in Figures 1, 2 and 3. The diagnosis of giant-cell pneumonia, which has been . . .