Bats and Histoplasmosis
Authors: P. D. KLITE
Journal: Annals of Internal Medicine (1965)

Article1 June 1965Bats and HistoplasmosisA Clinico-epidemiologic Study of Two Human CasesP. D. KLITE, M.D., RODOLFO V. YOUNG, M.D., F.A.C.P.P. D. KLITE, M.D., RODOLFO V. YOUNG, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-62-6-1263 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIt recently has been established in this laboratory that bats on the Isthmus of Panama are naturally infected with Histoplasma capsulatum (1) and that some genera are capable of shedding the fungus from intestinal lesions into their fecal contents (2).The occurrence of a febrile illness in two brothers presented the opportunity to relate natural infection in bats to human histoplasmosis. The results of epidemiologic studies designed to demonstrate this association are presented here.METHODSThe techniques for soil sampling have been described elsewhere (3). They consisted of two methods: a sedimentation technique that allowed for recovery of 0.05% of...References1. SHACKLETTEDIERCKSGALE MHFHNB: Histoplasma capsulatum recovered from bat tissues. Science 135: 1135, 1962. CrossrefMedlineGoogle Scholar2. KLITEDIERCKS PDFH: Histoplasma capsulatum in fecal contents and other organs of bats in the Canal Zone. Amer. J. Trop. Med. In press. Google Scholar3. KLITEKELLEYDIERCKS PDHBFH: A new soil sampling technique for pathogenic fungi. Amer. J. Epidem. 81: 131, 1965. CrossrefMedlineGoogle Scholar4. SEVER JL: Application of a microtechnique to viral serological investigations. J. Immun. 88: 320, 1962. MedlineGoogle Scholar5. HEINER DC: Diagnosis of histoplasmosis using precipitin reactions in agar gel. Pediatrics 22: 616, 1958. MedlineGoogle Scholar6. LEHANFURCOLOW PHML: Epidemic histoplasmosis. J. Chronic Dis. 5: 489, 1957. CrossrefMedlineGoogle Scholar7. GRAYSTONFURCOLOW JTML: The occurrence of histoplasmosis in epidemics-epidemiological studies. Amer. J. Public Health 43: 665, 1953. CrossrefGoogle Scholar8. LOOSLIGRAYSTONALEXANDERTANZI CGJTERF: Epidemiological studies of pulmonary histoplasmosis in a farm family. Amer. J. Hyg. 55: 392, 1952. MedlineGoogle Scholar9. ZEIDEBERGAJELLODILLONRUNYON LDLALL: Isolation of Histoplasma capsulatum from soil. Amer. J. Public Health 42: 930, 1952. CrossrefGoogle Scholar10. EMMONS CW: The significance of saprophytism in the epidemiology of the mycoses. Trans. NY Acad Sci. 17: 157, 1954. CrossrefMedlineGoogle Scholar11. SMITHWEEKS CDRJ: Isolation of Histoplasma capsulatum from soil by direct culture methods. Proc. Soc. Exp. Biol. Med. 115: 549, 1964. CrossrefMedlineGoogle Scholar12. EMMONS CW: Isolation of Histoplasma capsulatum from soil in Washington, D. C. Public Health Rep. 76: 591, 1961. CrossrefMedlineGoogle Scholar13. AJELLOBRICEÑO-MAAZCAMPINSMOORE LTHJC: Isolation of Histoplasma capsulatum from an oil bird (Steatornis caripensis) cave in Venezuela. Mycopatholgia 12: 199, 1960. Google Scholar14. EMMONS CW: Association of bats with histoplasmosis. Public Health Rep. 73: 590, 1958. CrossrefMedlineGoogle Scholar15. JACKSON D: Histoplasmosis, a "spelunker's" risk. Amer. Rev. Resp. Dis. 83: 261, 1961. MedlineGoogle Scholar16. CAMPINSZUBILLAGALOPEZDORANTE HCZLGM: An epidemic of histoplasmosis in Venezuela. Amer. J. Trop. Med. 5: 690, 1956. CrossrefMedlineGoogle Scholar17. MURRAYLURIEKAYEKOMINSBOROKWAY JFHIJCRM: Benign pulmonary histoplasmosis (cave disease) in South Africa. S. Afr. Med. J. 31: 245, 1957. MedlineGoogle Scholar18. GELFAND M: Cave disease: a report of three cases from Southern Rhodesia. Cent. Afr. J. Med. 8: 461, 1962. MedlineGoogle Scholar19. MANSON-BAHR PE: Histoplasmosis in East Africa. E. Afr. Med. J. 35: 625, 1958. MedlineGoogle Scholar20. AJELLOMANSON-BAHRMOORE LPEJL: Amboni caves, Tanganyika, a new endemic area for Histoplasma capsulatum. Amer. J. Trop. Med. 9: 633, 1960. CrossrefMedlineGoogle Scholar21. PONNAMPALAM J: Isolation of Histoplasma capsulatum from the soil of a cave in Central Malaya. Amer. J. Trop. Med. 12: 775, 1963. CrossrefMedlineGoogle Scholar22. TAYLORSHACKLETTEKELLEY RLMHHB: Isolation of Histoplasma capsulatum and Microsporum gypseum from soil and bat guano in Panama and the Canal Zone. Amer. J. Trop. Med. 11: 790, 1962. CrossrefMedlineGoogle Scholar23. EMMONSGREENHALL CWAM: Histoplasma capsulatum and house bats in Trinidad, W.I. Sabouraudia 2: 18, 1962. CrossrefGoogle Scholar24. AJELLOGREENHALLMOORE LAMJC: Occurrence of Histoplasma capsulatum on the island of Trinidad, B.W.I. Amer. J. Trop. Med. 11: 249, 1962. CrossrefMedlineGoogle Scholar25. IBACHLARSHFURCOLOW MJHWML: Epidemic histoplasmosis and airborne Histoplasma capsulatum. Proc. Soc. Exp. Biol. Med. 85: 72, 1954. CrossrefMedlineGoogle Scholar26. FURCOLOW ML: Epidemiology of histoplasmosis, in Histoplasmosis, edited by SWEANY, H. C., Charles C Thomas, Springfield, Ill., 1960, p. 130. Google Scholar27. EMMONSPIGGOTT CWWR: Eradication of Histoplasma capsulatum from soil. Mycologia 55: 521, 1963. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Balboa Heights, Canal ZoneFrom the U. S. Army Medical Research Unit component, the Middle America Research Unit, and the Chest Service, Gorgas Hospital, Balboa Heights, Canal Zone.Requests for reprints should be addressed to Middle America Research Unit, Box 2011, Balboa Heights, Canal Zone.*Antigens kindly supplied by Major Robert L. Taylor, Walter Reed Army Institute of Research. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDisseminated Histoplasmosis and Human Immunodeficiency Virus InfectionAnalysis of suppressor factor in delayed immune responses of a bat, PteropusgiganteusAn outbreak and review of cave-associated histoplasmosis capsulatiRole of bats in the ecology of Paracoccidioides brasiliensis : The survival of Paracoccidioides brasiliensis in the intestinal tract of frugivorous bat, Artibeus lituratusAcute Histoplasmosis Presenting as the Adult Respiratory Distress SyndromeDisseminated HistoplasmosisRecognition of changing sources in histoplasmic infectionMycoses of the alimentary tract of animalsHistoplasma capsulatum and chickens*Comparative Ecology of Respiratory Mycotic Disease AgentsThe focal occurrence of histoplasmosis in house-dwelling bats on the Isthmus of Panama 1 June 1965Volume 62, Issue 6Page: 1263-1271KeywordsAntigensBatsEpidemiologyHealth services researchHistoplasma capsulatumHistoplasmosisLesionsResearch laboratoriesThorax Issue Published: 1 June 1965 PDF downloadLoading ...