Combination Chemotherapy for Primary Amyloidosis Reconsidered.
Authors: HARVEY J. COHEN
Journal: Annals of Internal Medicine (1978)

Letters and Corrections1 October 1978Combination Chemotherapy for Primary Amyloidosis Reconsidered.HARVEY J. COHEN, M.D., F.A.C.P.HARVEY J. COHEN, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-89-4-572 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: The treatment of primary amyloidosis continues to be a difficult problem. Although secondary amyloidosis sometimes can be reversed by treatment of the underlying process, most attempts at treating primary amyloidosis have been unsuccessful (1). In April 1975 we reported our experience with a patient who had widespread primary amyloidosis with a severe nephrotic syndrome. After chemotherapy she experienced a complete clinical remission, and by electron microscopy we were able to document actual disappearance of amyloid from her bone marrow (2). Since the appearance of that report I have had many requests for follow-up information on that patient...References1. KYLEBAYRD RE: Amyloidosis: review of 236 cases. Medicine (Baltimore) 54:271-299, 1975 CrossrefMedlineGoogle Scholar2. COHENLESSINHALLALBURKHOLDER HLJP: Resolution of primary amyloidosis during chemotherapy. Studies in a patient with nephrotic syndrome. Ann Intern Med 82:466-473, 1975 LinkGoogle Scholar3. RAVIDROBSONKEDAR (KEIZMAN) MMI: Prolonged colchicine treatment in four patients with amyloidosis. Ann Intern Med 87:568-570, 1977 LinkGoogle Scholar4. RAVIDKEDAR (KEIZMAN)SOHAR MIE: Effect of a single dose of dimethyl sulfoxide on renal amyloidosis. Lancet 1:730-731, 1977 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: HARVEY J. COHEN, M.D., F.A.C.P.Affiliations: Department of Medicine Duke University School of Medicine Veterans Administration Hospital Durham, NC 27705 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDiagnosis and treatment of primary amyloidosisThe Long-Term Prognosis of AA and AL Renal Amyloidosis and the Pathogenesis of Chronic Renal Failure in Renal Amyloidosis*Primary localized amyloidosis of urethraTreatmentTherapeutic prospects in amyloidosisResponse of systemic amyloidosis to dimethyl sulfoxideResponse of Primary Hepatic Amyloidosis to Melphalan and Prednisone: A Case Report and Review of the LiteratureCardiac AmyloidosisLocalized amyloidosis of urethraSubepithelial argyrophilic spicular structures in renal amyloidosis—An aid in diagnosisPrim�re Amyloidose mit nephrotischem Syndrom: 5j�hriger Verlauf unter kombinierter ChemotherapieAmyloid Deposits and AmyloidosisSystemic amyloidosis and the skin: a review with special emphasis on clinical features and therapyAmyloidosis of the AL type 1 October 1978Volume 89, Issue 4Page: 572-573KeywordsAmyloidosisBone marrowChemotherapyCombination chemotherapyElectron microscopy ePublished: 1 December 2008 Issue Published: 1 October 1978 PDF downloadLoading ...