Bromocriptine for Inappropriate Thyrotropin Secretion
Authors: JOHN M.C. CONNELL
Journal: Annals of Internal Medicine (1982)

Letters and Corrections1 February 1982Bromocriptine for Inappropriate Thyrotropin SecretionJOHN M.C. CONNELL, M.B., DOUGLAS C. MCCRUDEN, B.SC., D.L. DAVIES, M.D., W. DONALD ALEXANDER, M.D.JOHN M.C. CONNELL, M.B.Search for more papers by this author, DOUGLAS C. MCCRUDEN, B.SC.Search for more papers by this author, D.L. DAVIES, M.D.Search for more papers by this author, W. DONALD ALEXANDER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-96-2-251 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: In the concluding paragraphs of the National Institutes of Health conference on inappropriate thyroid stimulating hormone (TSH) secretion, somatostatin or dopamine analogues were suggested as possible appropriate therapies in this condition (1). We write to report preliminary results of use of the dopamine agonist bromocriptine (Parlodel, Sandoz, Ltd, London, United Kingdom) in this condition.A 56-year-old white man presented with thyrotoxicosis in 1978, with an elevated serum free thyroxine (T4) of 164 nmol/L (normal range, 55 to 144 nmol/L); free triiodothyroxine (T3), 3 nmol/L (normal range, 0.9 to 2.8 nmol/L); and early (20 minutes) iodine uptake, 25%...References1. WEINTRUBGERSHENGORNKOURIDESFEIN BMIH. Inappropriate secretion of thyroid stimulating hormone. Ann Intern Med. 1981;95:339-51. LinkGoogle Scholar2. SCANLONMORASHALE MBD. Evidence for dopaminergic control of thyrotropin secretion in man. Lancet. 1977;2:421-3. CrossrefMedlineGoogle Scholar3. FEEKSAWERSBROWNSETHIRVINETOFT CJNJWA. Influence of thyroid status on dopaminergic inhibition of thyrotropin and prolactin secretions: evidence for an additional feedback mechanism in the control of thyroid hormone secretion. J Clin Endocrinol Metab. 1980;51:585-9. CrossrefMedlineGoogle Scholar4. BESSESBURROWSPAULDINGDONABED GGSI. Dopamine infusion acutely inhibits the TSH and prolactin response to TRH. J Clin Endocrinol Metab. 1975;41:985-8. CrossrefMedlineGoogle Scholar5. MIYAIONISHIHOSOKAWAISHIBASHIKUMAMARA KTMKY. Inhibition of thyrotropin and prolactin secretions in primary hypothyrodism by 2-Br-α-ergocryptine. J Clin Endocrinol Metab. 1974;39:391-4. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Gardiner Institute Western Infirmary Glasgow G11 6NT Scotland Royal Infirmary Glasgow G4 Scotland PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByThyroiditis and Other More Unusual Forms of HyperthyroidismThyroid-Stimulating Hormone-Mediated HyperthyroidismIndium-111 pentetreotide single-photon emission tomography in patients with TSH-secreting pituitary adenomas: Correlation with the effect of a single administration of octreotide on serum TSH levelsEscape phenomenon after successful bromocriptine and octreotide treatment in thyroid stimulating hormone secreting pituitary adenoma residual tissueTHYROTOXICOSIS DUE TO PITUITARY RESISTANCE TO THYROID HORMONES. SUCCESSFUL CONTROL WITH D THYROXINE: A STUDY IN THREE PATIENTSOther Forms of HyperthyroidismSevere hyperthyroidism due to neoplastic TSH hypersecretion in an old manThe Syndrome of Generalized Resistance to Thyroid Hormone (Grth)Abnormal daily periodicity of serum thyrotropin (TSH) and evidence for defective TSH suppression in a case of non-neoplastic syndrome of inappropriate TSH secretionDefective TSH Suppression in a Case of Non-Neoplastic Inappropriate TSH Secretion (ITSHS)Central Hypothyroidism and HyperthyroidismSuccessful treatment of hyperthyroidism due to nonneoplastic pituitary TSH hypersecretion with 3,5,3′-triiodothyroacetic acid (TRIAC) 1 February 1982Volume 96, Issue 2Page: 251-252KeywordsDopamineSomatostatinThyroid-stimulating hormoneThyroxineTriiodothyronine Issue Published: 1 February 1982 PDF DownloadLoading ...