Drug Allergy: Prevention, Diagnosis, and Treatment
Authors: Robert A. Goldstein, Roy Patterson
Journal: Annals of Internal Medicine (1984)

Editorials1 February 1984Drug Allergy: Prevention, Diagnosis, and TreatmentROBERT A. GOLDSTEIN, M.D., PH.D., ROY PATTERSON, M.D.ROBERT A. GOLDSTEIN, M.D., PH.D.Search for more papers by this author, ROY PATTERSON, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-100-2-302 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIt has been estimated that medical inpatients receive a total of 90 million courses of drug therapy per year and the frequency of adverse drug reactions is about 5% (1). By limiting the use of the term allergic to those reactions that are immunologically mediated or can reasonably be presumed to be, estimates are that drug allergy may account for 6% to 10% of these adverse reactions (2).Recognizing the magnitude of this problem, The National Institute of Allergy and Infectious Diseases noted that, if the knowledge gained from research findings in drug allergy could be widely used, it should...References1. LAWSONJICK DH. Drug prescribing in hospitals: an international comparison. Am J Public Health. 1976;66:644-8. CrossrefMedlineGoogle Scholar2. DE SWARTE R. Drug allergy. In: PATTERSON R, ed. Allergic Diseases Diagnosis and Management. 2nd ed. Philadelphia: J.B. Lippincott Co.; 1980:452-583. Google Scholar3. Asthma and The Other Allergic Diseases. Bethesda, Maryland: National Institutes of Health; DHEW publication no. 79-387. Google Scholar4. GOLDSTEINPATTERSON RR, eds. Proceedings of the Symposium on Drug Allergy: Prevention, Diagnosis and Treatment. J Allergy Clin Immunol. (In press). Google Scholar5. SOGNCASALECONDEMI DTJ. Interim results of the NIAID collaborative clinical trial of skin testing with major and minor penicillin derivatives in hospitalized adults [Abstract]. J Allergy Clin Immunol. 1983;71:147. CrossrefGoogle Scholar6. SULLIVANYECIESSHATZPARKERWEDNER TLGCH. Desensitization of patients allergic to penicillin using orally administered β-lactam antibiotics. J Allergy Clin Immunol. 1982;69:275-82. CrossrefMedlineGoogle Scholar7. GRAMMERCHENPATTERSON LPR. Evaluation and management of insulin allergy. J Allergy Clin Immunol. 1983;71:250-4. CrossrefMedlineGoogle Scholar8. GREENBERGERPATTERSONSIMONLIEBERMANWALLACE PRRPW. Pretreatment of high risk patients requiring radiocontrast media studies. J Allergy Clin Immunol. 1981;67:185-7. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByBiochemical Mechanisms of Drug ToxicityBiochemical Mechanisms of Drug ToxicityModulation of d-penicillamine-induced autoimmunity in the Brown Norway rat using pharmacological agents that interfere with arachidonic acid metabolism or synthesis of inducible nitric oxide synthaseThe danger hypothesis applied to idiosyncratic drug reactionsHaptenation of Sulfonamide Reactive Metabolites to Cellular ProteinsIN VIVO AND IN VITRO TESTING FOR ADVERSE DRUG REACTIONSCo-trimoxazole-induced hepatic injury — an analysis of cases with hypersensitivity-like reactions 1 February 1984Volume 100, Issue 2Page: 302-303KeywordsAdverse reactionsAllergy and immunologyDrug research and developmentDrug therapyDrugsInfectious diseasesInpatients Issue Published: 1 February 1984 PDF DownloadLoading ...