Leukemia and Hodgkin's Disease
Authors: MORTIMER J. LACHER
Journal: Annals of Internal Medicine (1963)

Case Studies1 September 1963Leukemia and Hodgkin's DiseaseMORTIMER J. LACHER, M.D., LEON N. SUSSMAN, M.D.MORTIMER J. LACHER, M.D.Search for more papers by this author, LEON N. SUSSMAN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-59-3-369 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlthough we can now look back upon 131 years of contemplation, speculation, and experimentation since Hodgkin's (1) first description of the disease that now bears his name, our knowledge of the true nature of the disease has not been increased materially.The following questions that Dameshek (2) asked in 1933 regarding Hodgkin's disease are pertinent today because they still remain unanswered: "Is it infectious or malignant in nature?" (Of course, with the revival of the virus theory in the etiology of cancer, it may be both infectious and malignant in nature.) "Is the type cell of lymphoid or reticuloendothelial origin?"...References1. HODGKIN T: On some marked appearances of absorbent glands and spleen. Medico-Chirug. Trans. 17: 68, 1832. CrossrefMedlineGoogle Scholar2. DAMESHEK W: Proliferative diseases of the reticulo-endothelial system. II. Aleukemic reticulosis. Folia Haemat. 49: 64, 1933. Google Scholar3. REED DM: On pathological changes in Hodgkins disease with especial reference to its relation to tuberculosis. Johns Hopk. Hosp. Rep. 10: 133, 1902. Google Scholar4. CRAVER LF: Clinical manifestations and treatment of leukemia. Amer. J. Cancer 26: 124, 1936. CrossrefGoogle Scholar5. GILLMCCALL AWAJ: Lymphadenoma and leukemia. Brit. Med. J. 1: 284, 1943. CrossrefMedlineGoogle Scholar6. GREENBERGCOHEN LHM: Histiomonocytic leukemia occurring in a patient with Hodgkin's disease. New York J. Med. 3817, 1962. 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EZDINLI, M.D., JOSEPH E. SOKAL, M.D., F.A.C.P., C. WILLIAM AUNGST, M.D., F.A.C.P., UNTAE KIM, M.D., AVERY A. SANDBERG, M.D.Lymphosarcoma during the course of myeloid leukaemia.Lymphocytic leukemia with coexistent localized reticulum cell sarcomaGranulomatous giant cell reticulosis associated with cases of treated leukaemiaChronic lymphocytic leukemia and Hodgkin's disease in the same patient.Report of a case, giving immunological and diagnostic considerations 1 September 1963Volume 59, Issue 3Page: 369-378KeywordsAutopsy pathologyBiopsyEtiologyHematology and oncologyHodgkin lymphomaInfectious diseasesLymphocytesLymphoma Issue Published: 1 September 1963 PDF downloadLoading ...