Chronic Phycomycosis in a Controlled Diabetic
Authors: J. HAROLD HELDERMAN
Journal: Annals of Internal Medicine (1974)

Letters1 March 1974Chronic Phycomycosis in a Controlled DiabeticJ. HAROLD HELDERMAN, M.D., HARRY S. COOPER, M.D., JOHN MANN, M.D.J. HAROLD HELDERMAN, M.D.Search for more papers by this author, HARRY S. COOPER, M.D.Search for more papers by this author, JOHN MANN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-80-3-419 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptHyperglycemia or ketoacidosis is the classic setting for phycomycetic infection in man (1, 2). We report here a case of rhinocerebral phycomycosis in a patient with controlled diabetes mellitus, with an unusual indolent and chronic, rather than acute, infection and with clinical and necropsy evidence of cure.A 55-year-old steel worker entered the hospital for the second time complaining of right frontal headache and a foul discharge from the right nostril (both having developed 1 month before), and sudden blindness. He had not had fever or weakness. Seven years before admission, he was seen for mild diabetic ketoacidosis; in the...References1. GREGORYGOLDENHAYMAKER JAW: Mucormycosis of the central nervous system. Bull Johns Hopkins Hosp 73:405-419, 1943 Google Scholar2. ABRAMSONWILSONARKY EDR: Rhinocerebral phycomycosis in association with diabetic ketoacidosis. Report of two cases and a review of clinical and experimental experience with amphotericin B therapy. Ann Intern Med 66:735-742, 1967 LinkGoogle Scholar3. BATTOCKGRAUSZBOBROWSKY DHM: Alternate-day amphotericin B therapy in the treatment of rhinocerebral phycomycosis (mucormycosis). Ann Intern Med 68:122-137, 1968 LinkGoogle Scholar4. SANDLERTALLMANKEAMY RCD: Successfully treated rhinocerebral phycomycosis in well controlled diabetes. N Engl J Med 285:1180-1182, 1971 CrossrefMedlineGoogle Scholar5. MOWATBAUM AJ: Chemotaxis of polymorphonuclear leukocytes from patients with diabetes mellitus. N Engl J Med 284:621-627, 1971 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Gerontology Research Center NIH NICHD Baltimore City Hospitals Baltimore, Maryland 21224 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByCase report: Disseminated pulmonary mucormycosis involving spleen in diabetic patient with aggressive surgical approachChronic rhino-orbito-cerebral mucormycosis: A case report and review of the literatureMucormicosis gastrointestinal en paciente diabético; reporte de un caso y revisión de la literaturaEpidemiology and Clinical Manifestations of MucormycosisZygomycosis: the re-emerging fungal infectionMucormycosis of the nose and paranasal sinusesChronic Rhinocerebral MucormycosisZygomycosisSystemic zygomycosis.Ocular and orbital phycomycosisChronic rhinocerebral phycomycosis in association with diabetes. 1 March 1974Volume 80, Issue 3Page: 419-419KeywordsBlindnessDiabetes mellitusFeversHeadachesHyperglycemiaRhinovirus infection Issue Published: 1 March 1974 PDF DownloadLoading ...