Metronidazole-Induced Pancreatitis
Authors: BENNETT H. PLOTNICK
Journal: Annals of Internal Medicine (1985)

Brief Reports1 December 1985Metronidazole-Induced PancreatitisBENNETT H. PLOTNICK, M.D., ISAAC COHEN, M.D., TATKIN TSANG, M.D., TIMOTHY CULLINANE, M.D.BENNETT H. PLOTNICK, M.D.Search for more papers by this author, ISAAC COHEN, M.D.Search for more papers by this author, TATKIN TSANG, M.D.Search for more papers by this author, TIMOTHY CULLINANE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-103-6-891 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptMetronidazole has been used to treat some infections and Crohn's disease. We report the first case of pancreatitis caused by metronidazole; there was recurrence on rechallenge.A 29-year-old black woman was first seen on 30 January 1984 with right upper quadrant abdominal and back pain of 3 days' duration. The patient had had a normal spontaneous vaginal delivery on 26 December 1983. Because of postpartum vaginal discharge and spotting, she had been started on metronidazole on 26 January 1984. The patient said she had not had pancreatitis, gallbladder, or liver disease; consumed ethanol recently; or previously used metronidazole. She had...References1. BERNSTEINFRANKBRANDTBOLEY LMLS. Healing of perineal Crohn's disease with metronidazole. Gastroenterology. 1980;79:357-65. CrossrefMedlineGoogle Scholar2. BRANDTBERNSTEINBOLEYFRANK LLSM. Metronidazole therapy for perineal Crohn's disease: a follow-up study. Gastroenterology. 1982;83:383-7. CrossrefMedlineGoogle Scholar3. ROSENURSINGALM ABT. A comparative study of metronidazole and sulfasalazine for active Crohn's disease: the cooperative Crohn's disease study in Sweden. I. Design and methodologic considerations. Gastroenterology. 1982;83:541-9. CrossrefMedlineGoogle Scholar4. URSINGALMBÁRÁNY BTF. A comparative study of metronidazole and sulfasalazine for active Crohn's disease: the cooperative Crohn's disease study in Sweden II. Result. Gastroenterology. 1982;83:550-62. CrossrefMedlineGoogle Scholar5. FINEGOLD S. Metronidazole. Ann Intern Med. 1980;93:585-7. LinkGoogle Scholar6. MALLORYKERN AF. Drug-induced pancreatitis: a critical review. Gastroenterology. 1980;78:813-20. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Evanston Hospital Evanston, Illinois PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByDrugs associated with drug-induced pancreatitis: focus on rarely discussed drugsDrug induced pancreatitis: A systematic review of case reports to determine potential drug associationsDrug-Induced Acute Pancreatitis in AdultsMetronidazole-Induced Pancreatitis: Is There Underrecognition? A Case Report and Systematic Review of the LiteraturePancreatic disorders in inflammatory bowel diseaseMetronidazolePancreatitis in Inflammatory Bowel DiseasesAcute pancreatitis in inflammatory bowel disease, with special reference to azathioprine-induced pancreatitisDrug-Induced PancreatitisDrug-Induced Acute Pancreatitis: An Evidence-Based ReviewAcute Pancreatitis in Patients With Crohnʼs Disease: Clinical Features and OutcomesMetronidazole and risk of acute pancreatitis: a population-based case-control studyAntibiotic prophylaxis in the initial management of severe acute pancreatitisMetronidazole-Induced Pancreatitis in a Patient with Recurrent Vaginal TrichomoniasisMetronidazole-Associated PancreatitisDrug-Associated Acute Pancreatitis: Twenty-One Years of Spontaneous Reporting in The NetherlandsReview article: Drug-induced pancreatitisCrohn’s disease associated with pancreatitis of unknown etiology: A case reportDrug-Induced PancreatitisToxicities of Antimicrobial Agents Used to Treat OsteomyelitisHow often does metronidazole induce pancreatitis?Drug-Induced Acute PancreatitisErythromycin-induced pancreatitisMetronidazole-Associated PancreatitisKurt A. Sanford, MD, James E. Mayle, MD, Howard A. Dean, DO, David S. Greenbaum, MD4 Drug-induced pancreatitisPancreatitis coincident with Crohn's ileocolitisAntiprotozoal drugs 1 December 1985Volume 103, Issue 6_Part_1Page: 891-892KeywordsCrohn's diseaseEthanolGallbladderHospital medicineInfectious diseasesInterleukinsLiver diseasesLower back painPancreatitis Issue Published: 1 December 1985 PDF DownloadLoading ...