Hepatitis G and Mixed Cryoglobulinemia
Authors: Patrice Cacoub
Journal: Annals of Internal Medicine (1997)

Letters15 June 1997Hepatitis G and Mixed CryoglobulinemiaPatrice Cacoub, MD, Lionel Frangeul, and Lucile Musset, PhDPatrice Cacoub, MDHopital la Pitie-Salpetriere, 75651 Paris, France, Lionel FrangeulHopital la Pitie-Salpetriere, 75651 Paris, France, and Lucile Musset, PhDHopital la Pitie-Salpetriere, 75651 Paris, FranceAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-126-12-199706150-00021 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:A new agent that may be responsible for acute and chronic hepatitis was recently identified [1, 2] and named hepatitis G virus (HGV). It is a single-stranded RNA virus that can be categorized as a member of the Flaviridiae family on the basis of its structure. It resembles hepatitis C virus (HCV), but its nucleotide sequence is too divergent to allow it to be classified as an HCV genotype. The estimated prevalence of HGV RNA, determined using reverse transcription polymerase chain reaction (PCR), is about 1% in healthy blood donors, 3% to 5% in patients receiving maintenance ...References1. Simons JN, Pilot-Matias TJ, Leary TP, Dawson GJ, Desai SM, Schlauder GG, et al. Identification of two flavivirus like genomes in the GB hepatitis agent. Proc Natl Acad Sci U S A. 1995; 92:3401-5. Google Scholar2. Linnen J, Wages J Jr, Zhang-Keck ZY, Fry KE, Krawczynski KZ, Alter H, et al. Molecular cloning and disease association of hepatitis G virus: a transfusion-transmissible agent. Science. 1996; 271:505-8. Google Scholar3. Masuko K, Mitsui T, Iwano K, Yamazaki C, Okuda K, Meguro T, et al. Infection with hepatitis GB virus C in patients on maintenance hemodialysis. N Engl J Med. 1996; 334:1485-90. Google Scholar4. Cacoub P, Lunel-Fabiani F, Musset L, Perrin M, Frangeul L, Leger JM, et al. Mixed cryoglobulinemia and hepatitis C virus. Am J Med. 1994; 96:124-32. Google Scholar5. Lunel F, Musset L, Cacoub P, Frangeul L, Cresta P, Perrin M, et al. Cryoglobulinemia in chronic liver diseases: role of hepatitis C virus and liver damage. Gastroenterology. 1994; 106:1291-300. Google Scholar Author, Article, and Disclosure InformationAffiliations: Hopital la Pitie-Salpetriere, 75651 Paris, France PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byLe virus GB-C ou virus « dit » de l'hépatite G est-il impliqué en pathologie humaine ?Lower expression of CD81 B-cell receptor in lymphoproliferative diseases associated with hepatitis C virus infectionTransfusion-associated TT virus co-infection in patients with hepatitis C virus is associated with type II mixed cryoglobulinemia but not with B-cell non-Hodgkin lymphomaCryoglobulinemia in Japanese patients with chronic hepatitis C virus infection: Host genetic and virological studyCryoglobulinsGB Virus C/Hepatitis G Virus (GBV-C/HGV): still looking for a diseaseMixed cryoglobulinemia: new conceptsCryoglobulinemic vasculitisHepatitis C virus but not GB virus C/hepatitis G virus has a role in type II cryoglobulinemiaNo association between hepatitis C and B-cell lymphomaHepatitis G virus: Molecular organization, methods of detection, prevalence, and disease associationPorphyria cutanea tarda and hepatitis G and C virus infectionHCV/HGV coinfection and cryoglobulinemia 15 June 1997Volume 126, Issue 12Page: 1002KeywordsAutoimmune diseasesHepatitis G virusInfectious diseasesMedical risk factorsNucleotide sequencingPolymerase chain reactionRNARNA virusesReverse transcriptionViremia Issue Published: 15 June 1997 Copyright & PermissionsCopyright © 1997 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...