Variants of Cardiopulmonary Manifestations of Manson's Schistosomiasis
Authors: Hans U. Wessel, Herbert M. Sommers, David W. Cugell, Milton H. Paul
Journal: Annals of Internal Medicine (1965)

Case Studies1 April 1965Variants of Cardiopulmonary Manifestations of Manson's SchistosomiasisReport of Two CasesHANS U. WESSEL, M.D., HERBERT M. SOMMERS, M.D., DAVID W. CUGELL, M.D., MILTON H. PAUL, M.D.HANS U. WESSEL, M.D.Search for more papers by this author, HERBERT M. SOMMERS, M.D.Search for more papers by this author, DAVID W. CUGELL, M.D.Search for more papers by this author, MILTON H. PAUL, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-62-4-757 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptChronic visceral schistosomiasis may lead to two distinct cardiopulmonary sequelae: [1] cor pulmonale due to obstructive hypertensive pulmonary vascular disease and [2] a cyanotic syndrome manifested by cyanosis, clubbing, arterial hemoglobin unsaturation for oxygen (oxygen unsaturation), and normal pulmonary artery pressures.Whereas discrete pulmonary lesions are commonly found in patients with schistosomiasis, the incidence of cor pulmonale is low and varies from 0.8 to 5.5% in autopsy material from different endemic areas (1-3). The pulmonary vascular lesions are due to embolization of schistosomal eggs, causing an allergic arteritis and paravascular granulomatous reaction. In Manson's schistosomiasis, extensive pulmonary lesions occur only...References1. SAMI A: Pulmonary manifestations of schistosomiasis. Dis. Chest 19: 698, 1951. CrossrefMedlineGoogle Scholar2. SHAWGHAREEB AFAA: The pathogenesis of pulmonary schistosomiasis in Egypt with special reference to Ayerza's disease. J. Path. Bad. 46: 401, 1938. CrossrefGoogle Scholar3. DE FARIA JL: Cor pulmonale in Manson's schistosomiasis I. Frequency in necropsy material: pulmonary vascular changes caused by schistosome ova. Amer. J. Path. 30: 167, 1964. Google Scholar4. RODRIQUEZFERNANDEZ-DURANGARCIA-MOLINERRIVERA HFLE: Cardio-pulmonary schistosomiasis. Amer. Heart J. 65: 253, 1963. CrossrefMedlineGoogle Scholar5. MARCHANDMARCIAL-ROJASRODRIQUEZPOLANCORIAZ EJRARGR: The pulmonary obstruction syndrome in Schistosoma Mansoni pulmonary endarteritis. Arch. Intern. Med. (Chicago) 100: 965, 1957. CrossrefGoogle Scholar6. ROLRIQUEZRIVERA HFE: Pulmonary schistosomiasis. New Eng. J. Med. 258: 1196, 1958. CrossrefMedlineGoogle Scholar7. FARIDGREERISHAKEL NAGAHLEGOLVANMOUSA ZJWKGAMGPAH: Chronic pulmonary schistosomiasis. Amer. Rev. Tuberc. 79: 119, 1959. Google Scholar8. DE FARIACZAPSKIRIBERO LEITEDE OLIVERA PENNAFUJIOKADE ULHOA CINTRA JLJMODTAB: Cyanosis in Manson's schistosomiasis. Amer. Heart J. 54: 196, 1957. CrossrefMedlineGoogle Scholar9. DE FARIAVALENTE BARBASFUJIOKALIONDE ANDRATASILVADECOURT JLJTMIEULV: Pulmonary schistosomatic arterio-venous fistulas producing a new cyanotic syndrome in Manson's schistosomiasis. Amer. Heart J. 58: 556, 1959. CrossrefMedlineGoogle Scholar10. MARCHANDDE JESUSRIVERA BIASCOECEA EJMZA: Cyanotic syndrome of portal hypertension in hepato-splenic schistosomiasis and portal cirrhosis. Amer. J. Cardiol. 10: 496, 1962. CrossrefMedlineGoogle Scholar11. WESSELKEDZICUGELL HUPDW: Respiratory and cardiovascular function in patients with severe pulmonary hypertension. Circulation 29: 825, 1964. CrossrefMedlineGoogle Scholar12. CALABRESIABELMAN PWH: Porto-caval and porto-pulmonary anastomosis in Laennec's cirrhosis and heart failure. J. Clin. Invest. 362: 1257, 1957. CrossrefGoogle Scholar13. FRITTSHARDEWIGROCHESTERDURANDCOURNAND HWADFJA: Estimation of pulmonary arterio-venous shunt flow using intra-venous injections of T 1824 and Kr 85. J. Clin. Invest. 39: 1841, 1960. CrossrefMedlineGoogle Scholar14. SHALDOMCAESARSHIANDUCCIWILLIAMSSCHEVILLESHERLOCK SJLHSES: The demonstration of porta-pulmonary anastomosis in portal cirrhosis with the use of radioactive krypton. New Eng. J. Med. 265: 410, 1961. CrossrefMedlineGoogle Scholar15. WARREN KS: Experimental pulmonary schistosomiasis. Trans. Roy. Soc. Trop. Med. Hyg. 58: 228, 1964. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Chicago, IllinoisFrom Northwestern University Medical School and The Children's Memorial Hospital, Chicago, Ill.This study was supported in part by training grant HTS 5344, U. S. Public Health Service, Bethesda, Md.Requests for reprints should be addressed to Hans U. Wessel, M.D., Children's Memorial Hospital, 707 Fullerton Ave., Chicago, Ill. 60614. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byLung Involvement in SchistosomiasisPulmonary schistosomiasisParasitic diseases of the GI tract in the United StatesCARDIOPULMONARY MANIFESTATIONS OF MANSON'S SCHISTOSOMIASIS 1 April 1965Volume 62, Issue 4Page: 757-766KeywordsHypertensionLesionsMedical servicesOxygenPathogenesisPolycythemiaPulmonary arteriesPulmonary vascular diseasesRespiratory physiologySchistosomiasis Issue Published: 1 April 1965 PDF downloadLoading ...