Colchicine and Secondary Amyloidosis
Authors: Ali Serdar Fak, Cetin Ozener, Emel Akoglu
Journal: Annals of Internal Medicine (1992)

Letters1 November 1992Colchicine and Secondary AmyloidosisAli Serdar Fak, MD, Cetin Ozener, MD, Emel Akoglu, MDAli Serdar Fak, MDSearch for more papers by this author, Cetin Ozener, MDSearch for more papers by this author, Emel Akoglu, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-117-9-795_3 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editors: We are writing to support the observations in the letter by Zemer and Langevitz that secondary amyloidosis could be treated with colchicine (1).We have followed a 52-year-old man with psoriatic arthritis for more than 10 years. He presented with skin rashes, deforming arthritis, mild uremia, and peripheral edema. His 24-hour urinary protein excretion was 2 g, and his creatinine clearance was 30 mL/minute. Renal biopsy showed amyloidosis, and he was started on topical agents for his skin rashes and on colchicine for amyloidosis. Thirty months later, peripheral edema and protenuria regressed. Serum creatinine and blood urea...References1. ZemerLangevitz DP. Reversal of the nephrotic syndrome by colchicine in amyloidosis of familial mediterranean fever. Ann Intern Med. 1992;116:426. LinkGoogle Scholar2. RavidRobsonKedar MMI. Prolonged colchicine treatment in four patients with amyloidosis. Ann Intern Med. 1977;87:568-570. LinkGoogle Scholar3. GertzKyle MR. Secondary systemic amyloidosis: response and survival in 64 patients. Medicine. 1991;70:246-56. CrossrefMedlineGoogle Scholar4. EscalanteEhresmannQuismorio AGF. Regression of reactive systemic amyloidosis due to ankylosing spondylitis following the administration of colchicine. Arthritis Rheum. 1991;34:920-2. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Marmara University School of Medicine Istanbul Turkey PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByMechanism of the anti-inflammatory effect of colchicine in rheumatic diseases: a possible new outlook through microarray analysisAmiloidosis secundaria como complicación de artropatía psoriásicaColchicine: Where to Use, Where Not to Use?Traitements des amyloses en dehors du traitement symptomatiqueRegression of nephrotic syndrome due to amyloidosis secondary to familial Mediterranean fever following colchicine treatmentColchicine: 1998 updateThe changing face of Familial Mediterranean FeverPharmacology of immunosuppressive medications used in renal diseases and transplantationRegression of the nephrotic syndrome in rheumatoid arthritis and amyloidosis treated with azathioprineTreatment of amyloidosisCOLCHICINE TREATMENT OF AA AMYLOIDOSIS OF FAMILIAL MEDITERRANEAN FEVERColchicine in the treatment of AA and AL amyloidosis 1 November 1992Volume 117, Issue 9Page: 795-796KeywordsAmyloidosisBloodColchicineCreatinineEdemaExcretionProteinsPsoriatic arthritisRashesUrea Issue Published: 1 November 1992 PDF DownloadLoading ...