Factors Influencing the Cure of Salmonella Carriers
Authors: BAYARD S. TYNES
Journal: Annals of Internal Medicine (1962)

Article1 December 1962Factors Influencing the Cure of Salmonella CarriersBAYARD S. TYNES, M.D., JOHN P. UTZ, M.D., F.A.C.P.BAYARD S. TYNES, M.D.Search for more papers by this author, JOHN P. UTZ, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-57-6-871 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTyphoid Mary is known to physicians and lay public as well. Although the medical journal (1) estimate of 53 cases and 3 deaths attributable to her is far below the 1,300 victims claimed in a recent article in Pageant (2), the salmonella carrier problem is still with us. Furthermore, nearly all cases of typhoid these days are from carrier contacts.This paper describes the role of antibiotic treatment and cholecystectomy in the control of the salmonella carrier state and reviews the reasons for the occasional failure.HISTORYCredit for the earliest concept of the fecal spread of typhoid or enteric...References1. SOPER A: The work of a chronic typhoid germ distributor. JAMA XLVIII: 2019, 1907. CrossrefGoogle Scholar2. SUFRIN M: Her name was Typhoid Mary. Pageant 154, October, 1961. Google Scholar3. BUDD W: The fever at the Clergy Orphan Asylum. Lancet 2: 617, 1856. CrossrefGoogle Scholar4. BUDD W: Intestinal fever: its mode of propagation. Lancet 2: 694, 1856. CrossrefGoogle Scholar5. VOGELSANG TM: Typhoid and paratyphoid B carriers and their treatment: experiences from western Norway. Grieg, Bergen, 1950, 368 pp. Google Scholar6. GEZON HM: Salmonellosis. DM, July, 1959. Google Scholar7. 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PULASKIFUSILLO EJMH: Gallbladder bile concentrations of the major antibiotics following intravenous administration. Surg. Gynec. Obstet. 100: 571, 1955. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Bethesda, MarylandFrom the National Institute of Allergy and Infectious Diseases, Laboratory of Clinical Investigation, National Institutes of Health, Bethesda 14, Maryland.Requests for reprints should be addressed to John P. Utz, M.D., National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda 14, Maryland. 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WOODWARD, M.D., F.A.C.P., JOSEPH E. SMADEL, M.D.Therapy of Acute Bacterial Gastroenteritis 1 December 1962Volume 57, Issue 6Page: 871-882KeywordsAntibioticsBileChloramphenicolClinical laboratoriesInfectious diseasesMedical servicesPenicillinResearch laboratoriesSalmonellaTyphoid Issue Published: 1 December 1962 CopyrightCopyright ©, 1962, by The American College of PhysiciansPDF DownloadLoading ...