<i>Pneumocystis carinii</i>Pneumonia
Authors: DAVID RIFKIND
Journal: Annals of Internal Medicine (1966)

Article1 November 1966Pneumocystis carinii PneumoniaStudies on the Diagnosis and TreatmentDAVID RIFKIND, PH.D., M.D., TANOUS D. FARIS, M.D., ROLLA B. HILL JR., M.D.DAVID RIFKIND, PH.D., M.D.Search for more papers by this author, TANOUS D. FARIS, M.D.Search for more papers by this author, ROLLA B. HILL JR., M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-65-5-943 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptPneumocystis carinii was first associated in Europe with the syndrome of interstitial plasma cell pneumonia occurring in premature and debilitated infants (1). This infection is now recognized to be of cosmopolitan distribution and to occur also in patients with hematopoietic malignancies (2-4), immunoglobulin defects (5, 6), and in those receiving corticosteroids and cytotoxic drug therapy (7).In a previous communication pneumonia associated with renal transplantation in six patients was described (7). In the single fatal case, autopsy revealed Pneumocystis carinii pneumonia and both pulmonary and disseminated cytomegalovirus infections.This communication summarizes the experience accumulated to date at this Center with...References1. GAJDUSEK DC: Pneumocystis carinii—etiologic agent of interstitial plasma cell pneumonia of premature and young infants. Pediatrics 19: 543, 1957. MedlineGoogle Scholar2. HENDRYPATRICK WSRL: Observations on thirteen cases of Pneumocystis carinii pneumonia. Amer. J. Clin. Path. 38: 401, 1962. CrossrefMedlineGoogle Scholar3. GILBERTFORDHAMBENSON CFCCWR: Death resulting from pneumocystis pneumonia in an adult. 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RIFKINDMARCHIOROWADDELSTARZL DTLWRTE: Infectious diseases associated with renal homotransplantation. II. Differential diagnosis and management. Ibid., p. 402. Google Scholar22. FRENKELGOODSHULTZ JKJTJ: Pathogenesis and chemotherapy of Pneumocystis carinii infection of rats. Progress in Protozoology, Excerpta Medica International Congress Series 91, p. 129, 1965. Google Scholar23. TAN-VINHCOCHARDVU-TRIEU-DONGSOLONAR LAW Diagnostic in vivo de la pneumonie a pneumocystis. Arch. Franc. Pediat. 20: 773, 1963. MedlineGoogle Scholar24. ROBBINSMILLERAREANPEARSON JBRHVMHA: Successful treatment of Pneumocystis carinii pneumonitis in a patient with congenital hypogammaglobulinemia. New Eng. J. Med. 272: 708, 1965. CrossrefMedlineGoogle Scholar25. IVÁDYPÁLDYUNGER GLG: Weitere Erfahrungen bei der Behandlung der interstitiellen plasmacellulären Pneumonie mit Pentamidin. Mschr. Kinderheilk. 111: 297, 1963. MedlineGoogle Scholar26. FRENKELGOODSHULTZ JKJTJ: Cortico-steroid-induced relapse of Pneumocystis infection of rats and its prevention with sulfadiazine-pyrimethamine therapy. Fed. Proc. 24: 614, 1965. Google Scholar27. FRENKELWEBERLUNDE JKRWMN: Acute toxoplasmosis. Effective treatment with pyrimethamine, sulfadiazine, leucovorin calcium, and yeast. JAMA 173: 1471, 1960. CrossrefMedlineGoogle Scholar28. FRENKELGOODSHULTZ JKJTJA: Latent pneumocystis infection of rats, relapse and chemotherapy. Lab. Med. In press. Google Scholar29. GERRARD JW: Pneumocystis pneumonia (letter). Canad. Med. Ass. J. 91: 88, 1964. Google Scholar30. MARSHALLFRENKEL WCJK: Pneumocystis carinii pneumonia(letter). Lancet 1 94, 1966. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Denver, ColoradoFrom the Departments of Medicine, Surgery, and Pathology, University of Colorado Medical Center, and the Veterans Administration Hospital, Denver, Colo.This study was supported in part by grant G-65-37 from the Life Insurance Medical Research Fund, Rosemont, Pa., and grants AM-06283, AM-06344, AI-07319-01, HE-07735, and AM-07772, the U. S. Public Health Service, Washington, D. C.This paper was presented at the 47th Annual Session of the American College of Physicians, New York, N. Y., April 18, 1966.Requests for reprints should be addressed to David Rifkind, M.D., University of Colorado Medical Center, Denver, Colo. 80220. 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POWELL JR., M.D., VINCENT T. DEVITA, M.D.Case 28-1967Systemic fungal infections complicating renal transplantation and immunosuppressive therapyThe Clinical Significance of Cytomegalovirus Infection in Renal Transplant RecipientsDAVID RIFKIND, PH.D., M.D., NEAL GOODMAN, M.D., ROLLA B. HILL JR., M.D.Death after transplantationInfectious diseases. Annual review of significant publications. 1 November 1966Volume 65, Issue 5Page: 943-956KeywordsCytomegalovirus infectionHospital medicinePneumocystisPneumocystis carinii pneumoniaPneumoniaPseudomonas infectionsPulmonary diseasesRenal transplantationResearch fundingSurgery Issue Published: 1 November 1966 PDF DownloadLoading ...