Obliterative Portal Venopathy of the Liver and "Idiopathic Portal Hypertension"
Authors: FRANK L. IBER
Journal: Annals of Internal Medicine (1969)

Editorial Note1 September 1969Obliterative Portal Venopathy of the Liver and "Idiopathic Portal Hypertension"FRANK L. IBER, M.D.FRANK L. IBER, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-71-3-660 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn 1962 a syndrome in 16 patients from northern India (New Delhi) with portal hypertension of insidious onset was described as distinct from both cirrhosis and extrahepatic obstruction of the portal vein (1). Subsequently, this disease was noted to be widespread in India and Japan and probably has been the cause throughout the world of some cases of portal hypertension of unknown cause (2).The original report from India has been amplified by a study of liver abnormalities of 6 patients at autopsy and 18 from liver biopsy (3). The most characteristic lesion observed was a marked subendothelial thickening, patchy...References1. RAMALINGASWAMI V, WIG KL, and SAMA SK: Cirrhosis of the liver in northern India: a clinicopathological study. Arch. Intern Med. (Chicago) 110: 350, 1962. CrossrefMedlineGoogle Scholar2. BOYER JL, SEN GUPTA KP, BISWAS SK, PAL NC, BASU MALLICK KC, IBER FL, and BASU AK: Idiopathic portal hypertension: comparison with the portal hypertension of cirrhosis and extrahepatic portal vein obstruction. Ann. Intern. Med. 66: 41, 1967. LinkGoogle Scholar3. NAYAK NC and RAMALINGASWAMI V: Obliterative portal venopathy of the liver. Arch. Path. (Chicago) 87: 359, 1969. MedlineGoogle Scholar4. REYNOLDS TB, HIDEMURA R, MICHEL H, and PETERS R: Portal hypertension without cirrhosis in alcoholic liver disease. Ann. Intern. Med. 70: 497, 1969. LinkGoogle Scholar5. IBER FL: The cause of portal hypertension. Amer. J. Med. Sci. 255: 217, 1968. CrossrefMedlineGoogle Scholar6. THOMPSON EN, WILLIAMS R, and SHERLOCK S: Liver function in extrahepatic portal hypertension. Lancet 2: 1352, 1964. CrossrefMedlineGoogle Scholar7. MADDREY WC, BASU MALLICK KC, IBER FL, and BASU AK: Extrahepatic obstruction of the portal venous system. Surg. Gynec. Obstet. 127: 989, 1968. MedlineGoogle Scholar8. MIKKELSEN WP, EDMONDSON HA, PETERS RL, REDEKER AG, and REYNOLDS TB: Extra- and intrahepatic portal hypertension with cirrhosis (hepatoportal sclerosis). Ann. Surg. 162: 602, 1965. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: FRANK L. IBER, M.D.Affiliations: Department of Medicine Lemuel Shattuck Hospital Boston, Mass. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAetiology and clinical outcomes of non-cirrhotic portal hypertension in SingaporeHistology of portal vascular changes associated with idiopathic non-cirrhotic portal hypertension: nomenclature and definitionIdiopathic Portal HypertensionPathology of idiopathic non-cirrhotic portal hypertensionVascular Disorders of the LiverObliterative Portal Venopathy: A Clinical and Histopathological ReviewNon-cirrhotic portal fibrosis related end stage liver disease in adults: evaluation from a study on living donor liver transplant recipientsIdiopathic noncirrhotic portal hypertensionIdiopathic portal hypertension in renal transplant recipients: Report of two casesIdiopathic portal hypertension (noncirrhotic portal fibrosis), thrombosis in portal venous system and protein C deficiency to the editorChronic splenomegaly in Nairobi, Kenya. II. Portal hypertensionPORTAL VEIN OR HEPATIC VEIN ?PATHOGENESIS OF PORTAL SCLEROSIS IN THE LIVER WITH IDIOPATHIC PORTAL HYPERTENSIONTropical SplenomegalyVinyl Chloride-Associated DiseaseIdiopathic portal hypertension (perisinusoidal fibrosis) after renal transplantation.Study of an epidemic of venoocclusive disease in India.Idiopathic portal hypertensionNoncirrhotic Presinusoidal Portal Hypertension Associated with Chronic Arsenical IntoxicationIntermittent Idiopathic Portal HypertensionNoncirrhotic portal fibrosisUltrastructure of the liver in non-cirrhotic portal fibrosis with portal hypertension 1 September 1969Volume 71, Issue 3Page: 660-661KeywordsAutopsyBiopsyCirrhosisLesionsLiverPortal hypertensionPortal veins ePublished: 1 December 2008 Issue Published: 1 September 1969 PDF downloadLoading ...