Carotid Disease and Cognitive Dysfunction
Authors: H.J.M. Barnett
Journal: Annals of Internal Medicine (2004)

Editorials17 February 2004Carotid Disease and Cognitive DysfunctionH.J.M. Barnett, CC, MDH.J.M. Barnett, CC, MDFrom King City, Ontario L7B 1K4, Canada.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-140-4-200402170-00013 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail The introduction of cerebral angiography in the 1930s by Moniz, followed by detailed postmortem studies of the cervical portion of the carotid artery in the 1950s by Miller Fisher, drew attention to the extracranial carotid artery's being more important than the middle cerebral artery in ischemic stroke (1). The description of the diagnostic features of carotid disease soon followed, and this led to strategies for preventing or eliminating carotid lesions. From the earliest writings, clinical investigators have debated a possible connection between severe carotid disease and impaired cognition. Few dispute the relationship between cognitive decline and large areas of infarction ...References1. Fisher M. Occlusion of the internal carotid artery. Arch Neurol Psych. 1951;65:346-77. CrossrefGoogle Scholar2. Johnston SC, O'Meara ES, Manolio TA, Lefkowitz D, O'Leary DH, Goldstein S, et al . Cognitive impairment and decline are associated with carotid artery disease in patients without clinically evident cerebrovascular disease. Ann Intern Med. 2004;140:237-47. LinkGoogle Scholar3. Powers WJ, Tempel LW, Grubb RL. Influence of cerebral hemodynamics on stroke risk: one-year follow-up of 30 medically treated patients. Ann Neurol. 1989;25:325-30. [PMID: 2785365] CrossrefMedlineGoogle Scholar4. Wade JP, Wong W, Barnett HJ, Vandervoort P. Bilateral occlusion of the internal carotid arteries. Presenting symptoms in 74 patients and a prospective study of 34 medically treated patients. Brain. 1987;110 Pt 3 667-82. [PMID: 3580828] CrossrefMedlineGoogle Scholar5. Endarterectomy for asymptomatic carotid artery stenosis. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study. JAMA. 1995;273:1421-8. [PMID: 7723155] CrossrefMedlineGoogle Scholar6. Barnett HJM, Meldrum H, Thomas DJ, Eliasziw M. Treatment of asymptomatic arteriosclerotic carotid artery disease. In: Barnett HJM, Bogousslavsky J, Meldrum H, eds. Ischemic Stroke.Advances in Neurology, Vol. 92. Philadelphia: Lippincott Williams & Wilkins; 2003:319-28. Google Scholar Author, Article, and Disclosure InformationAffiliations: From King City, Ontario L7B 1K4, Canada.Disclosures: None disclosed.Corresponding Author: H.J.M. Barnett, CC, MD, 14865, 7th Concession, King City, Ontario L7B 1K4, Canada; e-mail, [email protected]ca. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoCognitive Impairment and Decline Are Associated with Carotid Artery Disease in Patients without Clinically Evident Cerebrovascular Disease S. Claiborne Johnston , Ellen S. O'Meara , Teri A. Manolio , David Lefkowitz , Daniel H. O'Leary , Steven Goldstein , Michelle C. Carlson , Linda P. Fried , and W. T. Longstreth Jr. Metrics Cited ByThe evolving significance of carotid atherosclerosisAsymptomatic carotid stenosis is associated with cognitive impairmentCerebrovascular Disease in the ElderlyEffect of a Rho Kinase Inhibitor on Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion in RatsInfluence of Carotid Artery Stenting on Cognition of Elderly Patients with Severe Stenosis of the Internal Carotid ArteryPumps, Aqueducts, and Drought ManagementParticular aspects in patients with coronary heart disease and vascular cognitive impairmentCarotid Artery Occlusion and Stenosis 17 February 2004Volume 140, Issue 4Page: 303-304KeywordsArteriesBrainCarotid arteriesCarotid endarterectomyCognitionCognitive impairmentLesionsStenosisStrokeVascular diseases ePublished: 17 February 2004 Issue Published: 17 February 2004 CopyrightCopyright © 2004 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...