Recovery of Cytomegalovirus from Adults with Neoplastic Disease
Authors: CHARLES P. DUVALL
Journal: Annals of Internal Medicine (1966)

Article1 March 1966Recovery of Cytomegalovirus from Adults with Neoplastic DiseaseCHARLES P. DUVALL, M.D., ALBERT R. CASAZZA, M.D., PHILIP M. GRIMLEY, M.D., PAUL P. CARBONE, M.D., WALLACE P. ROWE, M.D.CHARLES P. DUVALL, M.D.Search for more papers by this author, ALBERT R. CASAZZA, M.D.Search for more papers by this author, PHILIP M. GRIMLEY, M.D.Search for more papers by this author, PAUL P. CARBONE, M.D.Search for more papers by this author, WALLACE P. ROWE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-64-3-531 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAcquired cytomegalic inclusion disease (salivary gland virus disease), though usually encountered as a disease of newborn infants, is being recognized with increasing frequency in adults with underlying malignant disease or with altered host defenses. Hill, Rowlands and Rifkind (1) have recently demonstrated the presence of cytomegalic inclusion bodies in the lungs of 20 of 39 patients who died after renal homotransplantation and drug-induced immune suppression, and Hedley-Whyte and Craighead (2) cultured cytomegalovirus from the lungs of such a patient.Antemortem isolation of cytomegalovirus from the urine has been accomplished in children with acute leukemia and other diseases (3), but the...References1. HILLROWLANDSRIFKIND RBDTD: Infectious pulmonary disease in patients receiving immunosuppressive therapy for organ transplantation. New Eng. J. Med. 271: 1021, 1964. CrossrefMedlineGoogle Scholar2. HEDLEY-WHYTECRAIGHEAD ETJE: Generalized cytomegalic inclusion disease after renal homotransplantation. New Eng. J. Med. 272: 473, 1965. CrossrefMedlineGoogle Scholar3. BENYESH-MELNICKDESSYFERNBACH MSIDJ: Cytomegaloviruria in children with acute leukemia and in other children. Proc. Soc. Exp. Biol. Med. 117: 624, 1964. CrossrefMedlineGoogle Scholar4. BODEYWERTLAKEDOUGLASLEVIN GPPTGRH: Cytomegalic inclusion disease in patients with acute leukemia. Ann. Intern. Med. 62: 899, 1965. LinkGoogle Scholar5. ROWEHARTLEYWATERMANTURNERHEUBNER WPJWSHCRJ: Cytopathogenic agent resembling human salivary gland virus recovered from tissue cultures of human adenoids. Proc. Soc. Exp. Biol. Med. 92: 418, 1956. CrossrefMedlineGoogle Scholar6. ROWEHARTLEYCRAMBLETTMASTROTA WPJWHGFM: Detection of human salivary gland virus in the mouth and urine of children. Amer. J. Hyg. 67: 57, 1958. MedlineGoogle Scholar7. RUEBNERHIRANOSLUSSERMEDEARIS BHTRJDN: Human cytomegalovirus infection: electron microscopic and histochemical changes in cultures of human fibroblasts. Amer. J. Path. 46: 477, 1965. MedlineGoogle Scholar8. MARGILETH AM: Diagnosis and treatment of generalized cytomegalic inclusion disease of the newborn. Pediatrics 15: 270, 1955. MedlineGoogle Scholar9. WONGWARNER TWNE: Cytomegalic inclusion disease in adults. Report of 14 cases with review of literature. Arch. Path. (Chicago) 74: 403, 1962. MedlineGoogle Scholar10. FISHERDAVIS ERE: Cytomegalic-inclusion disease in the adult. New Eng. J. Med. 258: 1036, 1958. CrossrefMedlineGoogle Scholar11. LEVINEWARNERJOHNSON RSNECF: Cytomegalic inclusion disease in the gastrointestinal tract of adults. Ann. Surg. 159: 37, 1964. CrossrefMedlineGoogle Scholar12. WELLERHANSHAWSCOTT THJBDE: Serologic differentiation of viruse responsible for cytomegalic inclusion disease. Virology 12: 130, 1960. CrossrefMedlineGoogle Scholar13. GEMZELL CA: Blood levels of 17-hydroxycorticoids in normal pregnancy. J. Clin. Endocr. 13: 898, 1953. CrossrefMedlineGoogle Scholar14. MEDEARIS DN: Observations concerning human cytomegalovirus infection and disease. Bull. Hopkins Hosp. 114: 181, 1964. MedlineGoogle Scholar15. WELLERHANSHAW THJB: Virologic and clinical observations on cytomegalic inclusion disease. New Eng. J. Med. 266: 1233, 1962. CrossrefMedlineGoogle Scholar16. NELSONWYATT JSJP: Salivary gland virus disease. Medicine (Balt.) 38: 223, 1959. CrossrefMedlineGoogle Scholar17. THALHAMMERROWE OWP: Gibt es im Raum von Wien Cytomegalie? Wien. Klin. Wschr. 72: 621, 1960. MedlineGoogle Scholar18. ZUBRODROSENBERGSHULMANKNIGHTROWEEDGCOMBHILBISH CGLNRVWPJTF: Unexplained death in a patient with leukemia. Ann. Intern. Med. 53: 1211, 1960. LinkGoogle Scholar19. CARBONESIEBERTGRIMLEY PPDPM: Unpublished observations. Google Scholar20. RIFKIND D: Cytomegalovirus infection after renal transplantation. Arch. Intern. Med. (Chicago) 116: 554, 1965. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Bethesda, MarylandFrom the Medicine Branch and Pathologic Anatomy Branch, National Cancer Institute, and the Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.Requests for reprints should be addressed to Charles P. Duvall, M.D., Medicine Branch, National Cancer Institute, National Institutes of Health, Bethesda, Md. 20014. 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PodiumsgesprächIncidence of antibody to eb virus, herpes simplex, and cytomegalovirus in hodgkin's diseaseChanging Concepts Concerning the Pathogenesis of Infectious Diseases*Opportunistic infections of the lungsGENERALIZED CYTOMEGALIC INCLUSION DISEASE IN AN ADULT, WITH PRIMARY SYSTEMIC INVOLVEMENT OF LYMPH NODES-CASE REPORT-Virus infections in patients with malignant disease.Toxoplasmosis complicating malignancy.Experience at the national cancer instituteISOLATION OF CYTOMEGALOVIRUS FROM THE BLOOD LEUCOCYTES OF A PATIENT WITH POST-TRANSFUSION MONONUCLEOSISCytomegalic inclusion disease in the adultA search for the reservoir of cytomegalovirus in salivary gland tissueHerpes-type virus infection in adult with hematologic disorder.Electron microscopic observations of virus and case reportCYTOMEGALOVIRUS INFECTION ASSOCIATED WITH PREGNANCYCytomegalovirus in the normal pregnant womanImmune Deficiencies, Aplastic Anemia and Abnormalities of Lymphoid Tissue in ThymomaThe Clinical Significance of Cytomegalovirus Infection in Renal Transplant RecipientsDAVID RIFKIND, PH.D., M.D., NEAL GOODMAN, M.D., ROLLA B. HILL JR., M.D.Infectious diseases. Annual review of significant publications.CYTOMEGALOVIRUS MONONUCLEOSIS WITH JAUNDICE AS PRESENTING SIGN 1 March 1966Volume 64, Issue 3Page: 531-541KeywordsAllergic diseasesCytomegalovirus infectionExcretionInfectious diseasesLungsOpportunistic infectionsResearch laboratoriesSalivaSalivary gland tumorsUrine Issue Published: 1 March 1966 PDF DownloadLoading ...