Thrombotic Thrombocytopenic Purpura in a Patient Who Subsequently Developed the Acquired Immunodeficiency Syndrome (AIDS)
Authors: Anthony C. Botti
Journal: Annals of Internal Medicine (1988)

Brief Reports1 August 1988Thrombotic Thrombocytopenic Purpura in a Patient Who Subsequently Developed the Acquired Immunodeficiency Syndrome (AIDS)Anthony C. Botti, MD, Phyllis Hyde, MD, Frank DiPillo, MDAnthony C. Botti, MDSearch for more papers by this author, Phyllis Hyde, MDSearch for more papers by this author, Frank DiPillo, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-109-3-242 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSeveral hematologic disorders coexist with the acquired immunodeficiency syndrome (AIDS). Cytopenias as well as hemostatic derangements have been described (1) in patients in both early and advanced stages of AIDS. An autoimmune thrombocytopenia has been described (2) in homosexual men positive for human immunodeficiency virus (HIV) antibody, and thrombocytopenia in an asymptomatic carrier may signal the onset of clinical disease. Recently, thrombotic thrombocytopenic purpura has been reported (3) in association with HIV antibody seropositivity in a homosexual man. We report the case of a patient with thrombotic thrombocytopenic purpura who subsequently developed AIDS.A 44-year-old black man was admitted because...References1. SpivakBenderQuinn JBT. Hematologic abnormalities in the acquired immunodeficiency syndrome. Am J Med. 1984;77:224-8. CrossrefMedlineGoogle Scholar2. MorrisDistenfeldAmorosiKarpatkin LAES. Autoimmune thrombocytopenic purpura in homosexual men. Ann Intern Med. 1982;96:714-7. LinkGoogle Scholar3. JokelaFlynnHenry JTK. Thrombotic thrombocytopenic purpura in a human immunodeficiency virus (HIV)-seropositive homosexual man. Am J Hematol. 1987;25:341-3. CrossrefMedlineGoogle Scholar4. RidolfiBell RW. Thrombotic thrombocytopenic purpura: report of 25 cases and review of the literature. Medicine (Baltimore). 1981;60:413-28. CrossrefMedlineGoogle Scholar5. Lian E. Pathogenesis of thrombotic thrombocytopenic purpura. Semin Hematol. 1987;24(2):82-100. MedlineGoogle Scholar6. Kwaan H. Clinicopathologic features of thrombotic thrombocytopenic purpura. Semin Hematol. 1987;24(2):71-81. MedlineGoogle Scholar7. SiddiquiLian FE. Platelet-agglutinating protein P37 from a thrombotic thrombocytopenic purpura plasma forms a complex with human immunoglobulin G. Blood. 1988;71:299-304. CrossrefMedlineGoogle Scholar8. Kwaan H. Miscellaneous secondary thrombotic microangiopathy. Semin Hematol. 1987;24(3):141-7. MedlineGoogle Scholar9. BocciaGelmannBakerMartiLongo TECGD. A hemolytic-uremic syndrome with the acquired immunodeficiency syndrome [Letter]. Ann Intern Med. 1984;101:716-7. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: From the Long Island College Hospital, Brooklyn, New York. For current author addresses, see end of text. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByThrombotic microangiopathies and HIV infection: Report of two typical cases, features of HUS and TTP, and review of the literatureManifestations Resembling Thrombotic Microangiopathy in Patients with Advanced Human Immunodeficiency Virus (HIV) Disease in a Cytomegalovirus Prophylaxis Trial (ACTG 204)The haemolytic uraemic syndrome in patients with AIDS.Hairy Cell Leukemia in Association with Thrombotic Thrombocytopenic Purpura and Factor VIII AntibodiesThrombotic microangiopathy and retroviral infections: A 13-year experienceThrombotic Thrombocytopenic Purpura as the Cause of Death in an HIV-Positive ChildPostoperative Complications in Patients With Human Immunodeficiency Virus DiseaseThrombotic thrombocytopenic purpura in patients with human immunodeficiency virus infection: A report of three cases and review of the literatureImmunologic thrombocytopenia followed by thrombotic thrombocytopenic purpura in two HIV1 patientsImproved Survival in Thrombotic Thrombocytopenic Purpura–Hemolytic Uremic SyndromeHematologic Abnormalities in AIDSHemostatic Abnormalities in HIV DiseaseThrombotic Thrombocytopenic Purpura With the Acquired Immunodeficiency Syndrome: A Pathologically Documented Case ReportThrombotic Thrombocytopenic Purpura Causing Sudden, Unexpected Death—A Series of Eight PatientsThrombotic Thrombocytopenic Purpura and Human T-Lymphotrophic Virus, Type 1 (HTLV-1)Andrew C. Dixon, MD, Denny W. Kwock, Jeffrey M. Nakamura, MD, Eugene T. Yanagihara, MD, Stanley M. Saiki, MD, Anne J. Bodner, PhD, Steven S. Alexander, PhDLetter to the editor: Association of thrombotic thrombocytopenia purpura (TTP) and human immunodeficiency virus (HIV) infection 1 August 1988Volume 109, Issue 3Page: 242-243KeywordsAIDSAutoimmune diseasesHIVHemostaticsHomosexualsIdiopathic thrombocytopenic purpuraThrombotic thrombocytopenic purpura Issue Published: 1 August 1988 Copyright© 1988 American College of PhysiciansPDF DownloadLoading ...