Self-induced Water Intoxication
Authors: J. ALLAN HOBSON
Journal: Annals of Internal Medicine (1963)

Case Studies1 February 1963Self-induced Water IntoxicationCase Study of a Chronically Schizophrenic Patient with Physiological Evidence of Water Retention Due to Inappropriate Release of Antidiuretic HormoneJ. ALLAN HOBSON, M.D., JOSEPH T. ENGLISH, M.D.J. ALLAN HOBSON, M.D., JOSEPH T. ENGLISH, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-58-2-324 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptReports of "self-induced" water intoxication (1-5) vary with experimental evidence of difficulty in producing the state in normal individuals (6). In view of the occurrence of abnormal water metabolism in some mentally ill patients (7, 8), it is of interest to note the high prevalence of pre-existing psychiatric disorder in patients with self-induced water intoxication (1-5, 9). Since predisposition to development of the syndrome has been shown to be associated with various other disease states (10-15), where is is attributable to well-known mechanisms, the operation of some such mechanism in the patients with mental disease who develop water intoxication should...References1. BARAHAL HS: Water intoxication in mental case. Psychiat. Quart. 12: 767, 1938. CrossrefGoogle Scholar2. SWANSONISERI AGOA: Acute encephalopathy due to water intoxication. New Engl. J. Med. 258: 831, 1958. CrossrefMedlineGoogle Scholar3. EMERY R: Water intoxication. Brit. Med. J. 2: 190, 1959. CrossrefGoogle Scholar4. CARTER TJ: Water intoxication. Brit. Med. J. 2: 367, 1959. CrossrefGoogle Scholar5. LANGGARDSMITH HWO: Self-induced water intoxication without predisposing illness. New Engl. J. Med. 266: 378, 1962. CrossrefMedlineGoogle Scholar6. ROWNTREE LG: Water intoxication. Arch. Intern. Med. 32: 157, 1923. CrossrefGoogle Scholar7. 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Quart. J. Exp. Physiol. 27: 343, 1938. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Bethesda, MarylandFrom the Laboratory of Clinical Science, National Institute of Mental Health, National Institutes of Health, United States Public Health Service, Department of Health, Education, and Welfare, Bethesda 14, Maryland.Requests for reprints should be addressed to J. Allan Hobson, M.D., Laboratory of Clinical Science, National Institute of Mental Health, National Institutes of Health, Bethesda 14, Maryland. 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PETERSON, M.D., WILLIAM H. MARSHALL, M.D.Fluphenazine and Inappropriate Secretion of Antidiuretic HormoneJORGE S. ZUNIGA, M.D., TOBY HAZAN, M.D.Syndrome of Inappropriate Secretion of Antidiuretic Hormone with Exacerbated PsychosisSTEVEN L. DUBOVSKY, M.D., STEPHEN GRABON, M.D., TOMAS BERL, M.D., ROBERT W. SCHRIER, M.D., F.A.C.P.COMA DUE TO WATER INTOXICATION IN BEER DRINKERSThe syndrome of inappropriate secretion of antidiuretic hormone"Inappropriate" secretion of antidiuretic hormone without corresponding hyponatraemia in cerebral pathologyExcretion of aldosterone in inappropriate secretion of antidiuretic hormone following head trauma 1 February 1963Volume 58, Issue 2Page: 324-332KeywordsAttentionClinical laboratory sciencesIngestionIntoxicationMedical servicesMetabolic disordersPrevention, policy, and public healthPsychiatry and mental healthResearch laboratoriesSchizophrenia Issue Published: 1 February 1963 PDF DownloadLoading ...