tbuckley/cabot-search huggingface dataset:
Breast Cancer Screening With Tomosynthesis and Digital Mammography—Reply
Authors: Sarah M. Friedewald, Elizabeth A. Rafferty, Emily F. Conant
Journal: JAMA (2014)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Effects of two antihistamine drugs on actual driving performance.
Authors: T Betts, D Markman, S Debenham, D Mortiboy, T McKevitt
Journal: BMJ (1984)

A double blind placebo controlled experiment was conducted measuring the effects of the centrally active antihistamine triprolidine and the peripherally acting antihistamine terfenadine on actual driving performance in a group of experienced women drivers. Triprolidine greatly impaired driving behaviour, whereas terfenadine did not. Triprolidine also impaired subjective and objective measures of mood and arousal, and despite an awareness that their driving was impaired while they were taking this agent subjects could not correct their performance. This study suggests that drivers who need antihistamine drugs should avoid those that act centrally.
ALCOHOL AND HUMAN EFFICIENCY
Authors: Emil Amberg
Journal: JAMA (1924)

<h3>To the Editor:</h3> —In connection with the editorial on "Alcohol and Human Efficiency" (The Journal, November 22), the following may be of interest: Gustav Aschaffenburg made experiments with type setters and published the results under the title, "Practical Work Under the Influence of Alcohol," in Psychologische Arbeiten, edited by Emil Kraepelin, Leipzig, Wilhelm Engelmann, 1896. He comes to these conclusions (p. 626): Even in the same occupation extending over many years, like type setting, there exists a not unimportant influence of practice. Moderate quantities of alcohol (36 to 40 gm.) diminished the working power. This influence was missed only once among eight experiments. It varied between 10.6 and 18.9 per cent., averaging 15.2 per cent, of the work which could have been expected, without fatigue and without loss of practice. Fatigue alone caused in the average only a loss of 6.5 per cent, of the expected amount of work. A
Pericardial Tamponade Following Percutaneous Left Ventricular Puncture
Authors: RICHARD J. BOTHAM, G. G. ROWE, W. P. YOUNG
Journal: Circulation (1959)

A case of pericardial tamponade following percutaneous left ventricular puncture for the assessment of aortic stenosis is presented. Technical factors pertinent to the etiology of the complication are discussed. Emphasis is placed on the fact that current enthusiasm for percutaneous ventricular puncture should be tempered with an awareness of the associated complications that may ensue and require immediate definitive therapy in an environment well equipped for their management.
Inpatient Psychiatry: Diagnosis and Treatment
Authors: Ann Halsell Appelbaum
Journal: JAMA (1992)

As a long-time teacher of psychiatric residents, but one who still remembers vividly the hunger of a young psychiatrist for an orderly approach to the chaos and unfamiliarity of the psychiatric hospital, I welcome this new version of Dr Sederer's text. He and a panel of distinguished contributors have addressed a wide range of topics within a book small enough to carry around for ready reference. The book is in two sections, of which the first takes up the diagnosis and treatment of the eight major diagnostic categories students most often encounter on inpatient psychiatric units, appropriately omitting the exotic, the controversial, and the less serious disturbances, except to mention them as part of differential diagnosis. The eight categories (depression, mania, schizophrenia, borderline character disorder, eating disorders, substance abuse, human immunodeficiency virus infection, and organic mental disorders) are treated with admirable clarity. Each chapter, after defining the disorder, offers a
RELATION OF THE MEDICAL PROFESSION IN THE TWENTIETH CENTURY TO THE TUBERCULOSIS PROBLEM.
Authors: S. A. KNOPF
Journal: JAMA (1901)

At no epoch in medical history has the tuberculosis problem been treated by the medical profession with more energy, more enthusiasm, and more success than at the present time. This awakening to the danger of tuberculosis, particularly in its pulmonary form, consumption, is primarily the result of the labors of four great men, Villemin<sup>1</sup>, Koch,<sup>2</sup>Cornet,<sup>3</sup>and Fränkel.<sup>4</sup>It was Villemin who first showed beyond a shadow of doubt the transmissibility of tuberculosis and its infectious character. To Koch we are indebted for the proof of the microbic origin of tuberculosis; to Cornet and his pupils for the demonstration of the infectiousness of tuberculous dust, and to B. Fränkel for the very interesting experiments in drop infection. From the works of the men whose names we have just mentioned we learned not only the true etiologic character of tuberculosis, but also how to prevent infection. The
Plasmacytoid Dendritic Cells Are Crucial for the Initiation of Inflammation and T Cell Immunity In Vivo
Authors: Hideaki Takagi, Tomohiro Fukaya, Kawori Eizumi, Yumiko Sato, Kaori Sato, Azusa Shibazaki, Haruna Otsuka, Atsushi Hijikata, Takashi Watanabe, Osamu Ohara, Tsuneyasu Kaisho, Bernard Malissen, Katsuaki Sato
Journal: Immunity (2011)
Occupational asthma due to indirect exposure to lauryl dimethyl benzyl ammonium chloride used in a floor cleaner.
Authors: P S Burge, M N Richardson
Journal: Thorax (1994)

The case is described of a 44 year old pharmacist who developed severe occupational asthma threatening his continued employment, confirmed by serial measurement of peak expiratory flow at home and work. The cause was found to be the cleaning agent used in his office when it was unoccupied. Bronchial challenge testing identified the specific agent to which he was sensitised as lauryl dimethyl benzyl ammonium chloride, a constituent of the floor cleaner. Substitution of this floor cleaner by a simple detergent cleaner led to a substantial improvement in his asthma, confirmed by repeated serial peak flow measurements.
The effect of molar mass and degree of hydroxyethylation on the controlled shielding and deshielding of hydroxyethyl starch-coated polyplexes
Authors: Matthäus Noga, Daniel Edinger, Raphaela Kläger, Seraphine V. Wegner, Joachim P. Spatz, Ernst Wagner, Gerhard Winter, Ahmed Besheer
Journal: Biomaterials (2013)
TUBERCULOSIS AND ITS PREVENTION.Read in the Section on State Medicine, at the Forty-fifth Annual Meeting of the American Medical Association, held at San Francisco. June 5-8, 1894.
Authors: WINSLOW ANDERSON
Journal: JAMA (1894)

Quarantine regulations are enacted and rigorously enforced in cases of cholera, smallpox and other contagious and infectious diseases, while the most dreadful scourge the human race has ever known—a disease which causes the death of more human lives than any and all other infectious and contagious diseases combined—is permitted to spread its frightful ravages without the slightest interference from medical, municipal, State or national authorities, and that disease is tuberculosis. Quarantine is declared against epidemics of a hundred or a thousand cases of cholera or yellow fever, and yet no laws reach consumption, although over 150,000 deaths occur annually in the United States from this disease alone. If this enormous death rate from any one disease does not constitute an epidemic, I should like to know what it might be termed. To indicate how it is contracted—for it is never inherited—it is only necessary to quote such high authority as
Diagnosis by endoscopic mucosal resection of a rare esophageal squamous cell carcinoma mimicking a subepithelial tumor
Authors: C.-S. Chuang, I.-L. Lee, K.-F. Lee, S.-Y. Tung, C.-S. Wu
Journal: Endoscopy (2007)

A 48-year-old man was diagnosed with an esophageal subepithelial tumor (SET) found incidentally. Esophagogastroduodenoscopy (EGD) revealed a SET in the lower third of the esophagus (36 cm away from the incisor) ([Fig. 1]). EUS confirmed a hypoechoic tumor, measuring 0.8 cm, in the submucosal layer ([Fig. 2]). Benign leiomyoma was the initial impression, and hence no aggressive therapy was performed. The tumor size and appearance remained apparently unchanged during the following 2 years. The last EGD examination showed some alteration. Another smaller SET was also found adjacent to the previous lesion ([Fig. 3]).
Prevalence and treatment of Staphylococcus aureus colonization in patients with mycosis fungoides and Sézary syndrome
Authors: R. Talpur, R. Bassett, M. Duvic
Journal: British Journal of Dermatology (2008)

Mycosis fungoides (MF) and Sézary syndrome (SS), variants of cutaneous T-cell lymphoma, may arise from antigen-driven clonal expansion and accumulation of helper-memory T cells. Superantigens from Staphylococcus aureus can stimulate T cells.(i) To determine the prevalence of S. aureus carriage in nares and skin in patients with MF/SS compared with historical rates in other conditions. (ii) To determine whether eradication of S. aureus carriage is associated with clinical improvement. Methods Skin and nares cultures were performed prospectively. Patients with positive nares and skin cultures were treated with oral antibiotics and intranasal mupirocin 2% and samples were taken for reculturing at 3 days, 4 weeks and 8 weeks. An exact binomial test was used to compare the carriage rates among different groups.Among 106 patients with MF/SS, 67 (63%) had skin colonization and 57 (54%) had nasal colonization. Staphylococcus aureus was isolated from 44 patients, 33 (31%) each from skin and nares. Colonization was highest in erythrodermic SS (48%), similar to atopic dermatitis (64%), and lowest in MF without erythroderma (26%), psoriasis (21%), and the general population (10%). Oral and topical antibiotics eradicated S. aureus colonization in nares in 28 of 33 (85%) patients and in MF skin lesions in 30 of 33 (91%) patients at 4-8 weeks, with rapid clinical improvement seen in 58% of S. aureus-colonized patients.Staphylococcal carriage in nares and skin lesions of patients with MF is similar to that in atopic dermatitis. Eradication of staphylococci from the skin is possible with treatment and was associated with clinical improvement.
Adalimumab Induces Deep Remission in Patients With Crohn's Disease
Authors: Jean–Frédéric Colombel, Paul J. Rutgeerts, William J. Sandborn, Mei Yang, Anne Camez, Paul F. Pollack, Roopal B. Thakkar, Anne M. Robinson, Naijun Chen, Parvez M. Mulani, Jingdong Chao
Journal: Clinical Gastroenterology and Hepatology (2013)
Chronic ethanol administration affects oxydative stress by ischemia/reperfusion in rat liver
Authors: M Simoncini, A Gasbarrini, G. Addolorato, P Pasini, B Nardo, F. Franceschi, A. De Luca, G. Vagni, E Roda, P Pola, M Bernardi, A Roda, G. Gasbarrini
Journal: Journal of Hepatology (1998)
Independent mechanisms of T cell-suppression by subpopulations of myeloid-derived suppressor cells (MDSC) in tumor-bearing hosts
Authors: Patrick L Raber, Paul Thevenot, Rosa Sierra, Dorota Wyczechowska, Maria E Ramirez, Augusto Ochoa, Cruz Velasco, Paulo C Rodriguez
Journal: Journal for ImmunoTherapy of Cancer (2013)

Meeting abstracts Suppression of effector immune responses by the tumor microenvironment remains a major obstacle in the development of new therapies for cancer. The accumulation of myeloid-derived suppressor cells (MDSC) in tumor-bearing hosts is a hallmark of malignancy-associated inflammation
Uncovering the biology of multiple myeloma among African Americans: a comprehensive genomics approach
Authors: Angela Baker, Esteban Braggio, Susanna Jacobus, Sungwon Jung, Dirk Larson, Terry Therneau, Angela Dispenzieri, Scott A. Van Wier, Gregory Ahmann, Joan Levy, Louise Perkins, Seungchan Kim, Kimberly Henderson, David Vesole, S. Vincent Rajkumar, Diane F. Jelinek, John Carpten, Rafael Fonseca
Journal: Blood (2013)
The role of microhomology in genomic structural variation
Authors: Diego Ottaviani, Magdalena LeCain, Denise Sheer
Journal: Trends in Genetics (2014)

Genomic structural variation, which can be defined as differences in the copy number, orientation, or location of relatively large DNA segments, is not only crucial in evolution, but also gives rise to genomic disorders. Whereas the major mechanisms that generate structural variation have been well characterised, insights into additional mechanisms are emerging from the identification of short regions of DNA sequence homology, also known as microhomology, at chromosomal breakpoints. In addition, functional studies are elucidating the characteristics of microhomology-mediated pathways, which are mutagenic. Here, we describe the features and mechanistic models of microhomology-mediated events, discuss their physiological and pathological significance, and highlight recent advances in this rapidly evolving field of research.
795–1 Quantitative Evaluation of Aortic Regurgitant Stroke Volume Using Vena Contracta Imaging by Color Doppler and Continuous Wave Doppler Echocardiography: An Animal Study with Quantified Aortic Insufficiency
Authors: Masahiro Ishii, Michael Jones, Takahiro Shiota, Izumi Yamada, Russell S. Heinrich, Ajit P. Yoganathan, David J. Sahn
Journal: Journal of the American College of Cardiology (1995)
Hyaluronic acid receptor-targetable imidazolized nanovectors for induction of gastric cancer cell death by RNA interference
Authors: Eunjung Kim, Jaemoon Yang, Hyun-Ouk Kim, Yonghee An, Eun-Kyung Lim, Gyudo Lee, Taeyun Kwon, Jae-Ho Cheong, Jin-Suck Suh, Yong-Min Huh, Seungjoo Haam
Journal: Biomaterials (2013)
Sickest patients to get free social care in their homes, says Gordon Brown
Authors: O. Ellis
Journal: BMJ (2009)

The UK prime minister, Gordon Brown, has announced a plan to provide free social care for adults with the most serious needs, which will allow them to stay in their own homes.

Speaking to the Labour party conference in Brighton, Mr Brown said that the current financial burden on people who need social care is unfair. The plans are a forerunner to a more comprehensive National Care Service, which is being developed by government.

“The people who face the greatest burden are too often those on middle incomes, who have savings that will last a year or two, but then they will see their savings slip away,” he said. …
Hydrogels in endovascular embolization. II. Clinical use of spherical particles
Authors: Daniel Horák, Franti šeksvec, Jaroslav Kálal, Arnold A. Adamyan, Yurii D. Volynskii, Olga S. Voronkova, Leonid S. Kokov, Klara Z. Gumargalieva
Journal: Biomaterials (1986)
Selection and Timing of Liver Transplantation in Primary Biliary Cirrhosis and Primary Sclerosing Cholangitis
Authors: Russell H. Wiesner, Michael K. Porayko, Rolland E. Dickson, Gregory J. Gores, Nicholas F. Larusso, Eileen J. Hay, Erik H. Wahlstrom, Ruud A.F. Krom
Journal: Hepatology (1992)

In summary, we answer the three questions we have previously posed: (a) Can liver transplantation prolong survival? Evolving data from several centers indicate that liver transplantation indeed prolongs survival in patients with PBC and PSC as compared with estimated survival using disease-specific risk scores based on the natural history of PBC and PSC. (b) Can we optimize timing of liver transplantation? Although many factors enter into the timing of liver transplantation, including when the patient is actually referred for liver transplantation and the individual desires of the patient to pursue liver transplantation, evidence is growing that having patients with chronic liver diseases like PBC and PSC undergo transplantation a little earlier in the course of the disease rather than waiting until the patients have experienced life-threatening complications or are on life-support measures can indeed improve early postliver transplant survival. In patients with PBC and PSC, the survival risk score, which reflects disease severity, can serve as an objective measurement to assess and evaluate the effect of liver disease severity on transplant outcome. Indeed, a number of studies have strongly suggested that optimal timing of liver transplantation may indeed be important to improve outcome, decrease morbidity and decrease cost. (c) Does the present allocation system in the United States allow for optimal use of our scarce donor organ resource?(ABSTRACT TRUNCATED AT 250 WORDS)
Neo-Fregeanism naturalized: The role of one-to-one correspondence in numerical cognition
Authors: Lieven Decock
Journal: Behavioral and Brain Sciences (2008)

Abstract Rips et al. argue that the construction of math schemas roughly similar to the Dedekind/Peano axioms may be necessary for arriving at arithmetical skills. However, they neglect the neo-Fregean alternative axiomatization of arithmetic, based on Hume's principle. Frege arithmetic is arguably a more plausible start for a top-down approach in the psychological study of mathematical cognition than Peano arithmetic.
Indoor Air Pollution and Blood Pressure in Adult Women Living in Rural China
Authors: Jill Baumgartner, James J. Schauer, Majid Ezzati, Lin Lu, Chun Cheng, Jonathan A. Patz, Leonelo E. Bautista
Journal: Environmental Health Perspectives (2011)

Almost half of the world's population uses coal and biomass fuels for domestic energy. Limited evidence suggests that exposure to air pollutants from indoor biomass combustion may be associated with elevated blood pressure (BP).Our aim was to assess the relationship between air pollution exposure from indoor biomass combustion and BP in women in rural China.We measured 24-hr personal integrated gravimetric exposure to fine particles < 2.5 µm in aerodynamic diameter (PM2.5) and systolic BP (SBP) and diastolic BP (DBP) in the winter and summer among 280 women ≥ 25 years of age living in rural households using biomass fuels in Yunnan, China. We investigated the association between PM2.5 exposure and SBP and DBP using mixed-effects models with random intercepts to account for correlation among repeated measures.Personal average 24-hr exposure to PM2.5 ranged from 22 to 634 µg/m3 in winter and from 9 to 492 µg/m3 in summer. A 1-log-µg/m3 increase in PM2.5 exposure was associated with 2.2 mm Hg higher SBP [95% confidence interval (CI), 0.8 to 3.7; p = 0.003] and 0.5 mm Hg higher DBP (95% CI, -0.4 to 1.3; p = 0.31) among all women; estimated effects varied by age group. Among women > 50 years of age, a 1-log-µg/m3 increase in PM2.5 exposure was associated with 4.1 mm Hg higher SBP (95% CI, 1.5 to 6.6; p = 0.002) and 1.8 mm Hg higher DBP (95% CI, 0.4 to 3.2; p = 0.01). PM2.5 exposure was positively associated with SBP among younger women, but the association was not statistically significant.PM2.5 exposure from biomass combustion may be a risk factor for elevated BP and hence for cardiovascular events. Our findings should be corroborated in longitudinal studies.
Magnetic resonance imaging findings in pulmonary Kaposi's sarcoma: a series of 10 cases
Authors: AM Khalil, MF Carette, JL Cadranel, CM Mayaud, GM Akoun, JM Bigot
Journal: European Respiratory Journal (1994)

Since chest X-ray and CT scan features of Kaposi's sarcoma (KS) are nonspecific, we wanted to test the hypothesis that the histological components of this tumour and/or the associated haemorrhagic component, may result in a characteristic signal pattern on magnetic resonance imaging (MRI). Thoracic MRI was performed in a prospective manner in ten patients with acquired immune deficiency syndrome (AIDS) and pulmonary KS. MRI examinations (1.5 Tesla) included Spin-echo T1 (SE-T1), before and after gadolinium injection, as well as T2-weighted sequences (SE-T2). For each sequence the signal intensity of lesions was measured and compared with each other as well as with the signal intensity of muscle. Results were compared to the hemosiderin content of macrophages in the bronchoalveolar lavage (BAL) in all patients and with histological findings in three. The results were compared to values obtained in a control group of seven patients with pneumocystis carinii pneumonia. SE-T1 showed focally increased signal intensity in the pulmonary parenchyma (n = 5). Signal enhancement in parenchymal lesions (n = 10) and along peribronchovascular trees (n = 5) was observed after gadolinium injection. The second echo of SE-T2 showed a markedly reduced signal intensity in pathologic areas (n = 10). This last finding was not observed in the control group. In conclusion, we have identified a pattern of MRI signal abnormalities suggestive of Kaposi's sarcoma. The MRI signal intensity of KS lesions may be related to the angiomatous and fibrous components of the tumour.(ABSTRACT TRUNCATED AT 250 WORDS)
Rheumatology for Clinicians
Authors: Max M. Montgomery
Journal: JAMA (1975)

<b>Clinical Rheumatology: A Problem-Oriented Approach to Diagnosis and Management</b>, by Roland W. Moskowitz, 331 pp, 129 illus, $14, Philadelphia, Lea &amp; Febiger, 1975. Fessel has written this book for the general internist practicing in the community. He indicates the frequency of rheumatological diagnoses: of 45,602 patient-visits to the department of medicine of the Permanente Medical Group Clinic in San Francisco during a six-month period, disorders of the musculoskeletal system accounted for 4,751. Only 0.9% of this number were for rheumatoid arthritis, whereas osteoarthritis, disk disease, and "soft tissue rheumatism" accounted for 8.4% of the visits. The author accepts these statistics as reasonably accurate and indicates in the preface that he devotes particular attention to problems causing most of the disability in community practice, and he describes rheumatology as it is seen in an urban community. The first chapter, "Common Pain Syndromes," includes cervical and lumbar syndromes, bursitis, and tenosynovitis. Of
The Basis of the FDA's Decision on Breast Implants
Authors: David A. Kessler
Journal: New England Journal of Medicine (1992)

On April 16, 1992, the Food and Drug Administration announced that breast implants filled with silicone gel would be available only through controlled clinical studies and that women who need such implants for breast reconstruction would be assured of access to these studies. This decision was especially difficult because even after more than 30 years of use involving more than 1 million women, adequate data to demonstrate the safety and effectiveness of these devices do not exist. They had been allowed to remain on the market after the enactment of the 1976 Medical Device Amendments (grandfathered) with the understanding that . . .
Myocardial Response to Acute Injury.
Authors: S. A REES
Journal: Cardiovascular Research (1993)

Journal Article Myocardial Response to Acute Injury. Get access SIAN A REES SIAN A REES London, UK Ed J R Parratt. (Pp 241; £50.00.) Basingstoke: Macmillan, 1992. ISBN 0-333-55712-3. Search for other works by this author on: Oxford Academic PubMed Google Scholar Cardiovascular Research, Volume 27, Issue 3, March 1993, Page 539, https://doi.org/10.1093/cvr/27.3.539a Published: 01 March 1993