Typhlitis in Patients with HIV-1 Infection
Authors: Michele Till, Narha Lee, William D. Soper, Robert L. Murphy
Journal: Annals of Internal Medicine (1992)

Brief Reports15 June 1992Typhlitis in Patients with HIV-1 InfectionMichele Till, MD, Narha Lee, MD, William D. Soper, MD, Robert L. Murphy, MDMichele Till, MDSearch for more papers by this author, Narha Lee, MDSearch for more papers by this author, William D. Soper, MDSearch for more papers by this author, Robert L. Murphy, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-116-12-998 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTyphlitis, also known as neutropenic enterocolitis or the ileocecal syndrome, is a well known cause of morbidity and mortality in neutropenic patients (1-6). Most patients with this syndrome have hematologic malignancies and have received antineoplastic chemotherapy. Typhlitis has not been reported to be a problem in patients with severe cellular immune deficiencies such as that caused by human immunodeficiency virus type 1 (HIV-1) infection; only two cases of probable neutropenic enterocolitis have been reported in patients with the acquired immunodeficiency syndrome (AIDS) (7). During a 15-month period, six patients with HIV-1 infection presented to our hospital with eight episodes of...References1. Newbold K. Neutropenic enterocolitis. Clinical and pathological review. Dig Dis. 1989;7:281-7. CrossrefMedlineGoogle Scholar2. KunkelRosenthal JD. Management of the ileocecal syndrome. Neutropenic enterocolitis. Dis Colon Rectum. 1986;29:196-9. CrossrefMedlineGoogle Scholar3. AltGlassSallinger BNH. Neutropenic enterocolitis in adults. Am J Surg. 1985;149:405-8. CrossrefMedlineGoogle Scholar4. MowerHawkinsNelson WJE. Neutropenic enterocolitis in adults with acute leukemia. Arch Surg. 1986;121:571-4. CrossrefMedlineGoogle Scholar5. ShakedShinarFreund AEH. Neutropenic typhlitis. A plea for conservatism. Dis Colon Rectum. 1983;26:351-2. CrossrefMedlineGoogle Scholar6. KoeaShaw JJ. Surgical management of neutropenic enterocolitis. Br J Surg. 1989;76:821-4. CrossrefMedlineGoogle Scholar7. CutronaBlinkhorneCrassSpagnuolo AJJP. Probable neutropenic enterocolitis in patients with AIDS. Rev Infect Dis. 1991;13:828-31. CrossrefMedlineGoogle Scholar8. RodgersKagnoff VM. Enteric immunologic defects and mucosal disease in HIV-1 infection. Seminars in Gastrointestinal Disease. 1991;2:17-24. Google Scholar9. EllisGuptaGalantHakimVandeVenJoy MSSSCC. Impaired neutrophil function in patients with AIDS or AIDS-related complex: a comprehensive evaluation. J Infect Dis. 1988;158:1268-76. CrossrefMedlineGoogle Scholar10. MurphyLaneFanciGallin PHAJ. Impairment of neutrophil bactericidal activity in patients with AIDS. J Infect Dis. 1988;158:627-9. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: Michele Till, MD; Narha Lee, MD; William D. Soper, MD; Robert L. Murphy, MDAffiliations: From Northwestern University Medical School, Chicago, Illinois. For current author addresses, see end of text. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAbdominal pain and fever in a patient with human immunodeficiency virus: a case reportInvestigation of typhlitis in bone marrow transplant patients in a stem cell transplant unitTyphlitis: A Real Pain in the Gut!Typhlitis as a complication of influenza in a patient with advanced HIV infectionComplications of HIV/AIDS and other secondary immunodeficienciesDiverticulitis and TyphlitisCritical Illness as a Result of Anti-Neoplastic TherapyReview article: the aetiology, investigation and management of diarrhoea in the HIV-positive patientTyphlitis due to mucormycosis after chemotherapy in a patient with acute myeloid leukemiaDiverticulitis and TyphlitisOther Diseases of the Colon and RectumTyphlite : à propos d’une observation et revue de la littératureDolor abdominal en un paciente oncológico39-Year-Old Man With Human Immunodeficiency Virus Infection and Abdominal PainNeutropenic enterocolitisSuccessful nonoperative management of typhlitis in pediatric oncology patientsNeutropenic enterocolitis: A rare presenting complication of acute leukemiaDiagnosis and Treatment of Colonic Disease in AIDSNeutropenic enterocolitis as a complication of high dose chemotherapy with stem cell rescue in patients with solid tumorsAcute Right Lower Quadrant Pain in a Patient With LeukemiaThalidomide-resistant HIV-associated aphthae successfully treated with granulocyte colony-stimulating factorCase 17-1994Typhlitis and HIVConnie Jumper, MD, J. John Weems Jr., MD, Ludwig A. Lettau, MD, MPH 15 June 1992Volume 116, Issue 12_Part_1Page: 998-1000KeywordsAIDSEnterocolitisHIV-1Hospital medicineImmune deficiencyInfectious diseasesInterleukinsMorbidityMortalitySurgery ePublished: 1 December 2008 Issue Published: 15 June 1992 PDF downloadLoading ...