Wegener Granulomatosis and Trimethoprim-Sulfamethoxazole
Authors: JOHN A. AXELSON
Journal: Annals of Internal Medicine (1987)

Letters and Corrections1 October 1987Wegener Granulomatosis and Trimethoprim-SulfamethoxazoleJOHN A. AXELSON, M.D., RAY H. CLARK, M.D., SIGMUND ANCEREWICZ, M.D.JOHN A. AXELSON, M.D.Search for more papers by this author, RAY H. CLARK, M.D.Search for more papers by this author, SIGMUND ANCEREWICZ, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-107-4-600_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Wegener granulomatosis is a disease characterized by necrotizing vasculitis of the upper and lower respiratory tracts, necrotizing glomerulonephritis, and differing degrees of disseminated small-vessel disease. The disease can range in severity from localized upper airway disease to the full-blown syndrome. We report the case of a patient with early Wegener granulomatosis confined to the nasal mucosa treated successfully with trimethoprim-sulfamethoxazole without previous immunosuppresant drugs.A 16-year-old girl presented with nasal pain and epistaxis. A crusting ulcerated lesion was noted. Cultures for bacteria and fungus were negative and she failed to respond to topical and systemic antibiotics. A...References1. DEREMEEMCDONALDWEILAND RTL. Wegener's granulomatosis: observation on treatment with antimicrobial agents. Mayo Clin Proc. 1985;60:27-32. CrossrefMedlineGoogle Scholar2. WESTTODDKING BJJ. Wegener granulomatosis and trimethoprim-sulfamethoxazole: complete remission after a twenty-year course. Ann Intern Med. 1987;106:840-2. LinkGoogle Scholar3. HALSTEADKARMODYWOLFF LCS. Presentation of Wegener's granulomatosis in young patients. Otolaryngol Head Neck Surg. 1986;94:368-71. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: JOHN A. AXELSON, M.D.; RAY H. CLARK, M.D.; SIGMUND ANCEREWICZ, M.D.Affiliations: 900 E. Michigan Avenue; Jackson, MI 49201 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byWegener's granulomatosis: A rare, chronic and multisystem diseaseANTIBIOTICS FOR THE TREATMENT OF RHEUMATOLOGIC SYNDROMESTherapy of vasculitisClinical Conference on Management DilemmasTreatment of vasculitis.Immunopharmacology of Vasculitic SyndromesProstatic Involvement in Wegener's GranulomatosisSulfonamides as antiinflammatory agents in the treatment of wegener's granulomatosisTraitement par le cotrimoxazole de la granulomatose de wegener (7 observations)Southwestern Internal Medicine Conference: Immune-complex Vasculitis: Role of Complement and IgG-Fc Receptor FunctionsThe treatment of wegener's granulomatosis with trimethoprim/sulfamethoxazole: illusion or vision?Response: the role of trimethoprim/sulfamethoxazole in the treatment of wegener's granulomatosis 1 October 1987Volume 107, Issue 4Page: 600-600KeywordsDrugsGlomerulonephritisLesionsMetastasisNasal mucosaPulmonary diseasesRespiratory systemUlcersVasculitisWegener granulomatosis ePublished: 1 December 2008 Issue Published: 1 October 1987 PDF downloadLoading ...