Bullous Pemphigoid and Intravenous Gammaglobulin
Authors: W. Godard, J. C. Roujeau, B. Guillot, C. Andre, G. Rifle
Journal: Annals of Internal Medicine (1985)

Letters and Corrections1 December 1985Bullous Pemphigoid and Intravenous GammaglobulinW. GODARD, J. C. ROUJEAU, B. GUILLOT, C. ANDRE, G. RIFLEW. GODARDSearch for more papers by this author, J. C. ROUJEAUSearch for more papers by this author, B. GUILLOTSearch for more papers by this author, C. ANDRESearch for more papers by this author, G. RIFLESearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-103-6-965_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Bullous pemphigoid, a severe autoimmune blistering disease, is usually treated with high doses of corticosteroids, immunosuppressive drugs, or plasma exchange (1). Because high-dose intravenous gammaglobulin can alleviate various antibody-mediated diseases (2-5) we decided to try gammaglobulin in patients with bullous pemphigoid.Eleven patients with biopsy-proven bullous pemphigoid were studied. They were seven men and four women aged 64 to 82 years (mean, 70). All had IgG linear deposits along the basement membrane zone in perilesional skin, and six had serum antiepidermal antibodies (by indirect immunofluorescence).Nine patients received 0.4 g/kg body weight · d of intravenous polyvalent...References1. ROUJEAUGUILLAUMEMOREL JJP. Plasma exchange in bullous pemphigoid. Lancet. 1984;2:486-9. CrossrefMedlineGoogle Scholar2. IMBACHD'APPUZZOHIRT PVA. High dose intravenous gammaglobulin for idiopathic thrombocytopenic purpura in childhood. Lancet. 1981;1:1228-31. CrossrefMedlineGoogle Scholar3. POLLACKCUNNIGHAM-RUNDLESSMITHWICK SCE. High dose intravenous gammaglobulin for auto-immune neutropenia. N Engl J Med. 1982;307:253. CrossrefMedlineGoogle Scholar4. JUNGHANSAHN RY. High dose intravenous gammaglobulin to suppress alloimmune destruction of donor platelets. Am J Med. 1984;30:204-8. CrossrefGoogle Scholar5. GAJDOSOUTINELKHARRAT PHD. High dose intravenous gammaglobulin for myasthenia gravis. Lancet. 1984;1:406-7. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: W. GODARD; J. C. ROUJEAU; B. GUILLOT; C. ANDRE; G. RIFLEAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byA randomized double-blind trial of intravenous immunoglobulin for bullous pemphigoidBritish Association of Dermatologists’ guidelines for the management of bullous pemphigoid 2012Treatment of subepidermal immunobullous diseasesIMMUNOMODULATORS AND THE “BIOLOGICS” IN CUTANEOUS EMERGENCIESThe use of i.v. 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PemphigoidIs there a scientific rationale for therapeutic plasma exchange or intravenous immune globulin in the treatment of acute guillain-barré syndrome?Die Therapie der bullösen DermatosenImmune modulating effects of intravenous immunoglobulin (IVIg) in autoimmune diseasesIntravenous gammaglobulin, 2: pharmacology, clinical uses and mechanisms of actionManagement of autoimmune disordersHigh-dose immunoglobulin therapy as an immunomodulatory treatment of rheumatoid arthritisRecent progress in the use of intravenous immunoglobulinManipulating the Immune System with Immune GlobulinIntravenous γ-globulin in myasthenia gravis: Interaction with anti-acetylcholine receptor autoantibodiesIntravenous immunoglobulin (IVIG) for the therapy of autoimmune disordersEffects of intravenous γ-globulin in pemphigusEffects of Repeated Doses of Intravenous Immunoglobulin in Myasthenia GravisImmediate effects of intravenous IgG administration on peripheral blood B and T cells and polymorphonuclear cells in patients with myasthenia gravis 1 December 1985Volume 103, Issue 6_Part_1Page: 965-965KeywordsAntibodiesAutoimmune diseasesBasement membraneBlood plasmaBody weightDrugsImmunofluorescenceImmunosuppressives ePublished: 1 December 2008 Issue Published: 1 December 1985 PDF downloadLoading ...