Famciclovir and Postherpetic Neuralgia
Authors: Stephen Tyring, Robin L. Saltzman, Robert Dworkin
Journal: Annals of Internal Medicine (1999)

Letters2 November 1999Famciclovir and Postherpetic NeuralgiaStephen Tyring, MD, PhD, Robin L. Saltzman, MD, and Robert Dworkin, PhDStephen Tyring, MD, PhDUniversity of Texas Medical Branch; Galveston, TX 77555 (Tyring)SmithKline Beecham Pharmaceuticals; Collegeville, PA (Saltzman)University of Rochester School of Medicine and Dentistry; Rochester, NY (Dworkin)Search for more papers by this author, Robin L. Saltzman, MDUniversity of Texas Medical Branch; Galveston, TX 77555 (Tyring)SmithKline Beecham Pharmaceuticals; Collegeville, PA (Saltzman)University of Rochester School of Medicine and Dentistry; Rochester, NY (Dworkin)Search for more papers by this author, and Robert Dworkin, PhDUniversity of Texas Medical Branch; Galveston, TX 77555 (Tyring)SmithKline Beecham Pharmaceuticals; Collegeville, PA (Saltzman)University of Rochester School of Medicine and Dentistry; Rochester, NY (Dworkin)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-131-9-199911020-00017 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:Bassett and colleagues' calculation of PHN incidence incorrectly assumes that the number of patients included in the “time to loss of PHN” analysis is the total number of patients with “long-term pain” in the entire study sample. In our original paper, the only patients included in the analysis were those who met the predefined study definition of PHN (that is, pain at or after healing). If the point at which lesions healed could not be determined, that patient could not be included in the analysis.To assess pain prevalence over time in the entire intention-to-treat sample, one must ...References1. Dworkin RH, Boon RJ, Griffin DR, Phung D. Postherpetic neuralgia: impact of famciclovir, age, rash severity, and acute pain in herpes zoster patients. J Infect Dis. 1998;178 Suppl 1 S76-80. CrossrefMedlineGoogle Scholar2. Famvir package insert. Physician's Desk Reference. Montvale, NJ: Medical Economics; 1999:3052-5. Google Scholar Author, Article, and Disclosure InformationAffiliations: University of Texas Medical Branch; Galveston, TX 77555 (Tyring)SmithKline Beecham Pharmaceuticals; Collegeville, PA (Saltzman)University of Rochester School of Medicine and Dentistry; Rochester, NY (Dworkin) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoFamciclovir for the Treatment of Acute Herpes Zoster: Effects on Acute Disease and Postherpetic Neuralgia: A Randomized, Double-Blind, Placebo-Controlled Trial Stephen Tyring , Rick A. Barbarash , James E. Nahlik , Anthony Cunningham , John Marley , Madalene Heng , Terry Jones , Ted Rea , Ron Boon , Robin Saltzman , and Famciclovir and Postherpetic Neuralgia Ken L. Bassett , Carolyn J. Green , and James M. Wright Metrics 2 November 1999Volume 131, Issue 9Page: 712-713KeywordsDrug marketingDrugsFood and Drug AdministrationIntent to treat analysisLesionsRashesRelative risk Issue Published: 2 November 1999 Copyright & PermissionsCopyright © 1999 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...