tbuckley/cabot-search huggingface dataset:
The Healthiest City: Milwaukee and the Politics of Health Reform
Authors: Norman Gevitz
Journal: JAMA (1982)

With the publication of Leavitt's book, there are now two major works concerned with the historical development of single municipal public health departments in the United States, the other being John Duffy's monumental two-volume record of the New York City experience. While the latter covers a much longer time span and is more comprehensive, Leavitt's opus does have certain advantages, particularly in regard to her major theme, understanding the process of health reform as it unfolded in the late 19th and early 20th centuries. Instead of chronicling how Milwaukee faced all its major public health problems, Leavitt chooses to focus on three illustrative issues—smallpox, garbage, and milk—representing, respectively, the larger areas of infectious disease, sanitation, and food control. In each of these well-researched sections, she examines how serious conflicts over policy based on economic interests, political ideology, and culture were handled and ultimately resolved. Most interesting is her discussion of
CaduCIS on CD-ROM
Authors: David A. Lacher
Journal: Annals of Internal Medicine (1999)

Medical Writings: Book Notes16 March 1999CaduCIS on CD-ROMDavid A. Lacher, MD and Matthew W. Morgan, MD, FRCPCDavid A. Lacher, MDAmerican College of Physicians-American Society of Internal Medicine, Philadelphia, Pennsylvania (Lacher)The Toronto Hospital, Toronto, Ontario, Canada. (Morgan)Search for more papers by this author and Matthew W. Morgan, MD, FRCPCAmerican College of Physicians-American Society of Internal Medicine, Philadelphia, Pennsylvania (Lacher)The Toronto Hospital, Toronto, Ontario, Canada. (Morgan)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-130-6-199903160-00022 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Philadelphia: Interactive Medical Review; 1998. Initial subscription price, $299.99; annual fee for updates. Order phone 215-823-5038.Field of medicine: Public health and general internal medicine.Format: CD-ROM software program with companion World Wide Web site.System requirements: Microsoft Windows 3.1, 95, 98, or NT. The minimum hardware configuration is a 486 66-MHz processor with 8 Mb of RAM, a CD-ROM drive, and 3 Mb of hard disk space. Accessing the Web site requires Netscape Navigator or Microsoft Internet Explorer, 3.0 or higher.Audience: Health care providers and hospital and managed care administrators interested in clinical and financial analysis of medical ... Author, Article, and Disclosure InformationAffiliations: American College of Physicians-American Society of Internal Medicine, Philadelphia, Pennsylvania (Lacher)The Toronto Hospital, Toronto, Ontario, Canada. (Morgan) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 16 March 1999Volume 130, Issue 6Page: 539KeywordsDatabasesHealth careHealth information technologyHospital medicineInformation storage and retrievalInpatientsInternational classification of diseases ninth revisionInternetMedicareStatistical data Issue Published: 16 March 1999 CopyrightCopyright © 1999 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...
REPORT OF A BRAIN WEIGHING 2,069 GRAMS (73 OUNCES).
Authors: CHARLES NELSON SPRATT
Journal: JAMA (1906)

<h3>Patient.</h3> —Mr. C. B., aged 42, died of meningitis, secondary to a chronic purulent otitis media. He was six feet two inches tall, weighed about 180 pounds, and was a lawyer by profession. <h3>Autopsy.</h3> —The autopsy, performed five hours after death, by Dr. Corbett, showed a thick fibrinous exudate at the base of the brain which extended upward over the convex surface to and along the longitudinal fissure, the infection having entered the cranial cavity along the facial nerve. The cord was cut at the foramen magnum. Without the dura the brain weighed 73 ounces (2,069 gms.). It was hardened in a 4 per cent. solution of formalin, and at the end of ten months weighed exactly 2,000 gms. (70.5 ounces). The cerebrum measured 19 em. in its anteroposterior diameter, 12 cm. vertically, and 14.5 cm. in the horizontal diameter. The average weight of the human brain, according to Quain,
Blocking Antibodies: Relationship between IgG4-associated Inhibitory Activity and Clinical Response to Grass-Pollen Immunotherapy
Authors: M. Shamji, C. Ljørring, J.N. Francis, I. Kimber, A.J. Frew, K. Lund, P.A. Würtzen, S.R. Durham
Journal: Journal of Allergy and Clinical Immunology (2010)
Propofol administration is safe in adult eosinophilic esophagitis patients sensitized to egg, soy, or peanut
Authors: J. Molina-Infante, A. Arias, D. Vara-Brenes, R. Prados-Manzano, J. Gonzalez-Cervera, M. Alvarado-Arenas, A. J. Lucendo
Journal: Allergy (2014)

Sedation might improve tolerability and adherence to endoscopic procedures in patients with eosinophilic esophagitis (EoE). Propofol administration is often contraindicated in patients with hypersensitivity to egg, soy, or peanut.To investigate the safety of propofol administration for procedural sedation in EoE patients sensitized/allergic to egg, soy, peanut.A retrospective observational study in adult EoE patients undergoing esophagogastroduodenoscopy with propofol sedation was conducted between January 2009 and March 2013. Food-specific serum IgE and skin prick tests for egg, soy, peanut, and cross-reactant foods were performed in all patients.Sixty EoE adult patients, mostly on food elimination diets (91%), were evaluated (age: 28 years (14-56), male gender (90%)). Atopy was present in 88% of patients, being the most prevalent comorbidities rhinoconjunctivitis (78%) and asthma (67%). Fifty-two patients (86%) were sensitized to either egg, soy, or peanut. Eighteen patients (28%) had a history of allergic reactions to egg, legumes, and nuts and strictly avoided these foods. A total of 404 upper endoscopies were performed under propofol sedation. No allergic adverse events were reported, except a transient bronchospasm after orotracheal intubation in an asthmatic adolescent receiving multiple drugs for anesthesia, in whom no sensitization to either propofol or its lipid vehicle was confirmed.Propofol was safely administered for procedural sedation in a large series of adult EoE patients multisensitized to egg, soy, peanut, showing one-third clinical allergy to these foods.
Sodium citrate versus saline catheter locks for non-tunneled hemodialysis central venous catheters in critically ill adults: a randomized controlled trial
Authors: Laure Hermite, Jean-Pierre Quenot, Abdelouaid Nadji, Saber David Barbar, Pierre-Emmanuel Charles, Maël Hamet, Nicolas Jacquiot, François Ghiringhelli, Marc Freysz
Journal: Intensive Care Medicine (2011)
STUDIES ON THE RELATION BETWEEN TUMOR SUSCEPTIBILITY AND HEREDITY. I
Authors: Clara J. Lynch
Journal: The Journal of Experimental Medicine (1924)

In this preliminary report there are presented some of the results obtained from crossing mice from tumor strains with males from other sources. The comparison of the tumor incidence in the inbred and backcross daughters, though the numbers given are small, supports the theory that the tendency to develop neoplasms is hereditary and the frequency with which tumors appear in the first filial generation of such crosses, indicates that the character is dominant. Additional experiments involving larger numbers are in progress.
ASSOCIATION OF SPORADIC LISTERIOSIS WITH CONSUMPTION OF UNCOOKED HOT DOGS AND UNDERCOOKED CHICKEN
Authors: Benjamin Schwartz, ClaireV Broome, GeriR Brown, AllenW Hightower, CarolA Ciesielski, Suzanne Gaventa, BruceG Gellin, Laurene Mascola, None Listeriosis Study Group
Journal: The Lancet (1988)
INDICATIONS FOR SCIENTIFIC PROGRESS IN STOMATOLOGY.CHAIRMAN'S ADDRESS BEFORE THE SECTION ON STOMATOLOGY, AT THE FIFTY-SIXTH ANNUAL SESSION OF THE AMERICAN MEDICAL ASSOCIATION, PORTLAND, ORE., JULY 11-14, 1905.
Authors: V. A. LATHAM
Journal: JAMA (1905)

In looking over the long list of papers to which we are to listen we are again struck with the enormous importance of the modern principles of dental surgery. You will pardon me when I emphasize the importance of the special study of diseases of the oral cavity and its surroundings, for I am jealous of the reputation of this Section. It is a matter of pride to show that we have not only held our work in respect but have been followed by a conservative country, i. e., England, which at the last meeting of the British Medical Association (1904) founded the Section on Dental Surgery, putting it in its right place in relation to the sciences of medicine and surgery. As a step forward this should do much to raise the standing of the dental profession and, more important still, to impress the general public. Dental surgeons now
Multiple Symmetric Lipomatosis: A Paradigm of Metabolically Innocent Obesity?
Authors: Michael Haap, Claus Thamer, Hans-Ulrich Häring, Rolf Markus Szeimies, Michael Stumvoll
Journal: Diabetes Care (2004)

We have recently suggested (1) that patients with multiple symmetric lipomatosis (MSL) may represent a paradigm for metabolically innocent fat accumulation. Harsch and colleagues (2,3) raise some justified words of caution with respect to the generalization of this statement. It is probably true that we cannot make general metabolic inferences on the syndrome of MSL as such based on our rather limited sample size. But this was not our intention, and we welcome the opportunity to clarify our line of argument.

The original idea was to present a situation where a substantial increase in body fat mass was not accompanied by decreased insulin sensitivity, which is in much contrast to common belief. …
Anorexia patient should not be subject to any more compulsory treatment, court rules
Authors: C. Dyer
Journal: BMJ (2014)

A High Court judge has ruled that any further detention and force feeding would be against the best interests of a young woman who has alternated for years between binge drinking and compulsory inpatient treatment for anorexia nervosa.1

Mr Justice Cobb declared that re-feeding the woman, named as Ms X, would not be in her best interests even though it would prolong her life. He also ruled that it would be lawful for the doctors looking after her at an unnamed NHS foundation trust not to give her nutrition and hydration against her will.

Ms X, the doctors caring for her, the official solicitor representing her, and an independent …
Diagnosis of Pneumocystosis
Authors: WALLACE J. MULLIGAN
Journal: Annals of Internal Medicine (1968)

Letters and Comments1 June 1968Diagnosis of PneumocystosisWALLACE J. MULLIGAN, M.D., GERALD L. BAUM, M.D.WALLACE J. MULLIGAN, M.D.Search for more papers by this author, GERALD L. BAUM, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-68-6-1373 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editor: It is with some interest that we read the two articles in the January issue of the ANNALS concerning Pneumocystis carinii. The paper by Vogel, Cohen, Powell, and DeVita is an excellent discussion; the point concerning the use of needle biopsy as a diagnostic procedure is well-taken, and we were happy to report the first case so diagnosed (1) although we are sure Dr. Vogel and associates' paper had been submitted before our presentation.The paper by Jarnum, Rasmussen, Ohlsen, and Sørensen, however, raises several major points for consideration. Rosen, Castleman, and Liebow (2) were the first...References1. MULLIGANKRAUSEBAUMMORINGSTAR WJFDGLW: Pneumocystis carinii infestation in adults: four cases with associated lymphoma. Ohio State Med. J. In press. Google Scholar2. ROSENCASTLEMANLIEBOW SHBAA: Pulmonary alveolar proteinosis. New Eng. J. Med. 258: 1123, 1958. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: WALLACE J. MULLIGAN, M.D.; GERALD L. BAUM, M.D.Affiliations: Pulmonary Section Veterans Administration Hospital Cleveland, Ohio 44106 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byMarasmus and pneumocystis carinii pneumonia in institutionalised infantsPneumocystis carinii PneumoniaPNEUMOCYSTIS CARINII PNEUMONIA AND PENTAMIDINE ISETHIONATE TOXICITYMICHAEL EMMER, M.D., VINCENT T. DEVITA, M.D. 1 June 1968Volume 68, Issue 6Page: 1373-1374KeywordsBiopsyPneumocystis ePublished: 1 December 2008 Issue Published: 1 June 1968 PDF downloadLoading ...
Failure of Thrombus to Resolve in Urokinase-Type Plasminogen Activator Gene–Knockout Mice
Authors: I. Singh, K.G. Burnand, M. Collins, A. Luttun, D. Collen, B. Boelhouwer, A. Smith
Journal: Circulation (2003)

Background— Monocytes may have an important role in the resolution of venous thrombosis. Increased expression of tissue-type plasminogen activator (tPA) and urokinase-type plasminogen activator (uPA) is associated with an ingress of monocytes into the thrombus. This study was designed to evaluate the importance of these activators in thrombus resolution. Methods and Results— Inferior caval vein thrombosis was induced in cohorts of adult wild-type, uPA gene-knockout (uPA −/− ), and tPA gene-knockout (tPA −/− ) mice in a flow model. Thrombi were harvested from wild-type and uPA −/− mice (n=60 per group) between 1 and 60 days. Thrombi were also obtained from groups of wild-type and tPA −/− mice (n=24 per group) between 1 and 28 days. Thrombus size and macrophage content were measured by computer-assisted image analysis. Thrombus resolution was significantly impaired in the uPA −/− mice compared with wild-type controls ( P &lt;0.0001) but was unaffected in tPA −/− mice. Monocyte content in wild-type mice was highest at 14 days after thrombus induction and was ≈4 times greater than in uPA −/− mice ( P =0.0043). Thrombus size in uPA −/− mice transplanted with wild-type marrow (0.29±0.06 mm 2 ) was significantly smaller than in uPA −/− mice given uPA −/− bone marrow (3.9±1.1 mm 2 ) ( P =0.0022). Donor bone marrow–derived cells expressing LacZ were present in the thrombus after transplantation. Conclusions— The resolution of experimental venous thrombus is dependent on uPA but is unaffected by the absence of tPA. Absence of uPA is also associated with delayed monocyte recruitment into the thrombus. Transplanting wild-type bone marrow restores thrombus resolution in uPA −/− animals, suggesting an important role for bone marrow–derived cells in this process.
Multiple Distal Pulmonary Arterial Thromboses Revealed by Lung Scintigraphy in a Patient With Homocystinuria and Normal Multidetector CT Pulmonary Angiography
Authors: Laurent Tessonnier, Eric Guedj, Aline Cano, Serge Cammilleri, Andreea Dragulescu, Brigitte Chabrol, Olivier Mundler
Journal: Clinical Nuclear Medicine (2008)

Patients with homocystinuria are at high risk to develop vascular thrombosis, both arterial and venous. We report the case of an asymptomatic noncompliant 13-year-old child referred for pulmonary arterial hypertension, revealed in the follow-up of a pyridoxine nonresponsive form of homocystinuria. Simultaneous dual-isotope Kr-81m ventilation/Tc-99m MAA perfusion SPECT demonstrated multiple areas of absent radioactivity, which were consistent with distal pulmonary arterial thromboses. By contrast, multidetector CT pulmonary angiography was normal. The role of lung scintigraphy in the management of the disease is reviewed and discussed.
Dynamic Clinical Studies With Radioisotopes and the Scintillation Camera
Authors: Gerald Burke
Journal: JAMA (1966)

The scintillation camera has been used for dynamic studies of renal function with sodium iodohippurate I 131 (Hippuran). This approach permits constant visual monitoring of the passage of iodohippurate I 131 through the parenchyma and pelvis of the kidney concomitant with the inscription of the renogram curve. It thus permits more definitive interpretation of the renogram since it allows direct, rather than intuitive, correlation of the various segments of the renogram curve with the intrarenal location and transit of iodohippurate I 131 at that time. Several variations and abnormalities of renogram contour have been characterized in this manner. The results obtained indicate that scintillation-camera renography may be a useful adjunct in the evaluation of renal function under both clinical and experimental conditions.
Medicine in Europe: A Guide to Funding for Medical, Dental and Veterinary Research Workers
Authors: T. Richards
Journal: BMJ (1996)

A J S Davies, D Dodd European Commission, ECU 10, pp 83 ISBN 92 827 4196 6

The European dream has hit a rough patch, with Euro politics dominated by doubt over the feasibility and even desirability of economic and monetary union. However, interest in European health policy and how it should develop is growing, and although some visions well exceed the limited capacity of the European Commission to respond, it is a healthy sign. As is the new readiness of the commission to listen to outside advice. Choices in Health Policy is a good example of this. Its last four pages consist of 26 recommendations on the role of …
Early Change in Patient-Reported Health During Lung Cancer Chemotherapy Predicts Clinical Outcomes Beyond Those Predicted by Baseline Report: Results From Eastern Cooperative Oncology Group Study 5592
Authors: David T. Eton, Diane L. Fairclough, David Cella, Susan E. Yount, Philip Bonomi, David H. Johnson
Journal: Journal of Clinical Oncology (2003)

Purpose: To determine the ability of longitudinal patient-reported health (PRH) scores to enhance prediction of clinical outcomes beyond baseline scores. Patients and Methods: In 573 advanced non–small-cell lung cancer patients enrolled in a phase III clinical trial, we used baseline and 6-week follow-up PRH scores to predict best response to treatment, disease progression, and survival. Using regression analyses, we tested the predictive ability of the five subscales of the Functional Assessment of Cancer Therapy–Lung (physical, functional, social/family, emotional well-being, and the lung cancer subscale) as well as the trial outcome index (TOI) aggregate score. Results: After clinical factors were controlled for, baseline physical well-being (PWB) and TOI scores predicted all three clinical outcomes. A higher baseline PWB score was associated with a better response to treatment (odds ratio, 1.09; P &lt; .001) and lower risk of death (risk ratio, 0.95; P &lt; .001). Higher baseline TOI score was associated with a lower risk of disease progression (risk ratio, 0.98; P &lt; .001). These two baseline predictors (PWB and TOI) were then used along with 6-week change scores to classify patients into four groups: low baseline-declined, low baseline-improved, high baseline-declined, and high baseline-improved. Patients with low baseline-declined PWB scores showed the worst responses to treatment and survived the shortest duration. Patients with low baseline-declined TOI scores had the shortest time to progression. Conclusion: The physical aspects of baseline PRH and PRH change during chemotherapy are significant predictors of clinical outcomes in lung cancer. This has implications for patient stratification in clinical trials and may aid decision-making in clinical practice.
Reply to YiJun Shen and DingWei Ye's Letter to the Editor re: Gregory R. Pond, Andrew J. Armstrong, Brian A. Wood, et al. Evaluating the Value of Number of Cycles of Docetaxel and Prednisone in Men With Metastatic Castration-Resistant Prostate Cancer. Eur Urol 2012;61:363–9
Authors: Guru Sonpavde, Gregory R. Pond, Andrew J. Armstrong
Journal: European Urology (2011)
Hypothermia for Traumatic Brain Injury — A Good Idea Proved Ineffective
Authors: Raj K. Narayan
Journal: New England Journal of Medicine (2001)

Traumatic brain injury is an important cause of death and disability in both civilians and military personnel.1 In areas with organized trauma care systems and adequate critical care, the mortality from severe traumatic brain injury appears to have been lowered from approximately 50 percent in the 1970s to 30 percent more recently. More important, this reduction in mortality has been associated with an increase in the proportion of survivors with relatively normal cerebral function. However, this remarkable achievement is not widely recognized. These improvements can be ascribed to the more rapid transportation of patients to emergency departments, the avoidance of . . .
(9) Poikiloderma congenitale (Rothmund-Thomson's disease)
Authors: J.L. Burton
Journal: British Journal of Dermatology (1977)

Journal Article (9) Poikiloderma congenitale (Rothmund‐Thomson's disease) Get access J.L. Burton J.L. Burton Brisrol Children's Hospital Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 97, Issue s15, 1 December 1977, Page 37, https://doi.org/10.1111/j.1365-2133.1977.tb14317.x Published: 01 December 1977
TOXICITY OF EMETINE
Authors: Charles F. Craig
Journal: JAMA (1933)

To the Editor:  —In the review on amebic dysentery  the November 18 issue ofThe Journal,  discussing the treatment, the statement is made: In the chronic cases Craig recommends continuous treatment with emetine bismuth iodide or chiniofon. It is apparent that the writer quoted from my article  Musser's Practice of Medicine, but  that article it is definitely stated that in chronic amebic dysentery, during the acute exacerbations the treatment should be with emetine bismuth iodide or chiniofon. It will be noted that continuous treatment with emetine bismuth iodide is not recommended but that the use of this drug is limited to treatment during the acute exacerbations of the chronic type of amebic dysentery.  I would appreciate this statement being corrected  a future issue ofThe Journal, as it has apparently caused the impression that I recommend continuous treatment with emetine, which is far from the
Anticonvulsants and thyroid function.
Authors: J Finucane
Journal: BMJ (1978)

intracranial metastases is well documented4-8 47-80 O of unselected patients with intracranial metastases may be expected to obtain symptomatic relief with cranial irradiation5-8 and about 120o are still alive and active one year later.These results are obtained without the stress to the patient of a major operation.We hope these details will encourage the general physician to consider irradiation as a palliative measure for patients with cerebral metastases.