Rapid Brain Calcification after Ischemic Stroke
Authors: Robert J. Wityk, Donna Lapeyrolerie, Barry D. Stein
Journal: Annals of Internal Medicine (1993)

Brief Reports15 September 1993Rapid Brain Calcification after Ischemic StrokeRobert J. Wityk, MD, Donna Lapeyrolerie, MD, and Barry D. Stein, MDRobert J. Wityk, MDFrom Johns Hopkins School of Medicine and Sinai Hospital of Baltimore, Baltimore, Maryland., Donna Lapeyrolerie, MDFrom Johns Hopkins School of Medicine and Sinai Hospital of Baltimore, Baltimore, Maryland., and Barry D. Stein, MDFrom Johns Hopkins School of Medicine and Sinai Hospital of Baltimore, Baltimore, Maryland.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-119-6-199309150-00008 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Calcium deposition in the brain, readily detectable on computed tomographic (CT) scan, has many possible causes [1-6]. Calcification of an ischemic infarction is rare and is thought to occur months to years after the acute event [2, 5]. We describe a patient who had extensive brain calcification after ischemic stroke. Brain calcification in this patient occurred during a 6-week period in the setting of uremia and hyperphosphatemia.Case ReportA 63-year-old man with a history of hypertension, alcohol abuse, and renal failure (for which he received maintenance hemodialysis) was admitted after having left-sided weakness and slurred speech for 1 day. ...References1. Lowenthal A. Striopallidodentate calcifications. In: Vinken PJ, Bruyn GW, Klawans HL; eds. Handbook of Clinical Neurology. v. 5. Extrapyramidal Disorders. New York: Elsevier Science Publishers B.V.; 1986:417-36. Google Scholar2. Kuzuhara S, Naito Y, Namura Y, Takahashi R, Chiba K. CT demonstration of calcification within old cerebral infarcts. Comput Assist Tomogr. 1985; 9:268-71. Google Scholar3. Swartz JD, Faerber EN, Singh N, Polinsky MS. CT demonstration of cerebral subcortical calcifications. J Comput Assist Tomogr. 1983; 7:476-8. Google Scholar4. Midroni G, Willinsky R. Rapid postanaoxic calcification of the basal ganglia. Neurology. 1992; 42:2144-6. Google Scholar5. Kapila A. Calcification in cerebral infarction. Radiology. 1984; 153: 685-7. Google Scholar6. Franke CL, van Swieten JC, van Gijn J. Residual lesions on computed tomography after intracerebral hemorrhage. Stroke. 1991; 22: 1530-3. Google Scholar7. Parfitt AM. Soft-tissue calcification in uremia. Arch Intern Med. 1969; 124:544-56. Google Scholar8. Southwood RL, Mueller BA, Copley JB. Soft tissue calcification in renal failure. Ann Pharmacother. 1990; 24:855-9. Google Scholar9. Alfrey AC. Chronic renal failure: manifestations and pathogenesis. In: Schrier RW, ed. Renal and Electrolyte Disorders. Second edition. Boston: Little, Brown and Company; 1980: 409-42. Google Scholar10. Akmal M, Goldstein DA, Multani S, Massry SG. Role of uremia, brain calcium, and parathyroid hormone on changes in electroencephalogram in chronic renal failure. Am J Physiol. 1984; 15:575-9. Google Scholar Author, Article, and Disclosure InformationAuthors: Robert J. Wityk, MD; Donna Lapeyrolerie, MD; Barry D. Stein, MDAffiliations: From Johns Hopkins School of Medicine and Sinai Hospital of Baltimore, Baltimore, Maryland.Corresponding Author: Robert J. Wityk, MD, Division of Neurology, Department of Medicine, Sinai Hospital of Baltimore, 2401 West Belvedere Avenue, Baltimore, MD 21215-5271. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byCortical calcifications in ischemic strokeEarly extensive gyral calcification in ischemic strokeGyriform calcifications after ischemic stroke in a patient with primary hyperparathyroidismCo-occurrence of a novel PDGFRB variant and likely pathogenic variant in CASR in an individual with extensive intracranial calcifications and hypocalcaemiaA 44-year-old man with eye, kidney, and brain dysfunctionAggressive gyriform calcifications and seizures after ischemia stroke in a patient with primary hyperparathyroidismIntracranial Calcifications 15 September 1993Volume 119, Issue 6Page: 490-491KeywordsBrainBrain diseasesCalciumComputed axial tomographyInfarctionIschemic strokeLungsPhosphatesStrokeUrea ePublished: 15 August 2000 Issue Published: 15 September 1993 Copyright & PermissionsCopyright © 1993 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...