Necrotizing Nocardial Pneumonitis
Authors: HAROLD C. NEU
Journal: Annals of Internal Medicine (1967)

Article1 February 1967Necrotizing Nocardial PneumonitisHAROLD C. NEU, M.D., MARGARITA SILVA, PH.D., ELIZABETH HAZEN, PH.D., SIDNEY H. ROSENHEIM, M.D.HAROLD C. NEU, M.D.Search for more papers by this author, MARGARITA SILVA, PH.D.Search for more papers by this author, ELIZABETH HAZEN, PH.D.Search for more papers by this author, SIDNEY H. ROSENHEIM, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-66-2-274 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptNocardiosis has classically been considered a chronic, suppurative disease involving the lungs, skin, or brain. In man,Nocardia asteroidesis the principal pathogen, but other species are occasionally implicated in human diseases. Nocardiosis is thought to be a fairly rare disease although reviews in recent years have demonstrated an increasing prevalence of the disease (1-3). The infection is primarily pulmonary with metastatic lesions in virtually every other organ of the body. The role ofNocardia asteroidesas an opportunist in patients with underlying disease and particularly those patients on adrenocortical steroid therapy has been stressed by a number of authors...References1. MURRAYFINEGOLDFROMANWILL JFSMSDW: The changing spectrum of nocardiosis. A review and presentation of nine cases. Amer. Rev. Resp. Dis. 83: 315, 1961. MedlineGoogle Scholar2. SALTZMANCHICKCONANT HAEWNF: Nocardiosis as a complication of other diseases. Lab. Invest. 11: 1110, 1962. MedlineGoogle Scholar3. HATHAWAYMASON BMKN: Nocardiosis. Study of fourteen cases. Amer. J. Med. 32: 903, 1962. CrossrefMedlineGoogle Scholar4. ANDRIOLEBALLASWILSON VTMGL: The association of nocardiosis and pulmonary alveolar proteinosis. A case study. Ann. Intern. Med. 60: 266, 1964. LinkGoogle Scholar5. 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HOSTYMCDURMONTAJELLOGEORGBRUMFIELDCALIX TSCLLKGLAA: Prevalence of Nocardia asteroides in sputa examined by a tuberculosis diagnostic laboratory. J. Lab. Clin. Med. 58: 107, 1961. MedlineGoogle Scholar13. RAICHCASEYHALL RAFWH: Pulmonary and cutaneous nocardiosis. The significance of the laboratory isolation of Nocardia. Amer. Rev. Resp. Dis. 83: 505, 1961. MedlineGoogle Scholar14. FREESEYOUNGSEALYCONANT JWWGWCNF: Pulmonary infection by Nocardia asteroides. Findings in eleven clinical cases. J. Thorac. Cardiov. Surg. 46: 537, 1963. CrossrefMedlineGoogle Scholar15. CROSSBINFORD RMCH: Is Nocardia asteroides an opportunist? Lab. Invest. 11: 1103, 1962. MedlineGoogle Scholar16. HIDDLESTONE HJ: Nocardiosis in New Zealand. Report of a case. New Zeal. Med. J. 56: 399, 1957. MedlineGoogle Scholar17. STRAUSSKLIGMANPILLSBURY REAMDM: The chemotherapy of actinomycosis and nocardiosis. Amer. Rev. Tuberc. 63: 441, 1951. Google Scholar18. RUNYON EH: Nocardia asteroides: studies of its pathogenicity and drug sensitivities. J. Lab. Clin. Med. 37: 713, 1951. MedlineGoogle Scholar19. PELLEGRINOHENDERSON EDRR: Response of pulmonary nocardiosis to treatment with massive doses of penicillin intravenously. Report of a successfully treated case with four-year follow-up observation, together with review of the literature. Amer. Rev. Resp. Dis. 84: 242, 1961. MedlineGoogle Scholar20. RIVERAPEREZ JVJB: Pulmonary nocardiosis treated with chloramphenicol. Arch. Intern. Med. (Chicago) 100: 152, 1957. CrossrefGoogle Scholar21. MUNSLOW RA: Actinomycotic (Nocardia asteroides) brain abscess with recovery. J. Neurosurg. 11: 399, 1954. CrossrefMedlineGoogle Scholar22. RHOADESRILEYMUCHMORE ERHDHG: Cycloserine in the treatment of human nocardiosis. Antimicrob. Agents Chemother. p. 352, 1961. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, New YorkFrom the Departments of Medicine, Dermatology, and Pathology, College of Physicians and Surgeons, Columbia University, New York, N. Y.Dr. Neu is a Career Scientist of the New York City Health Research Council.Requests for reprints should be addressed to Harold C. Neu, M.D., Department of Medicine, Columbia University, 630 W. 168th St., New York, N. Y. 10032. 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Etude clinique et microbiologiquePyridine Extraction of Nocardial Acid FastnessObservations on paraffin baiting as a laboratory diagnostic procedure in nocardiosisPulmonary Nocardiosis Complicating Malignant Lymphoma Successfully Treated with ChemotherapyINFLUENCE OF REJECTION THERAPY ON FUNGAL AND NOCARDIAL INFECTIONS IN RENAL-TRANSPLANT RECIPIENTSNocardia asteroides infection complicating neoplastic diseaseCOMPLICATED NOCARDIOSIS SUCCESSFULLY TREATED WITH TRIMETHOPRIM AND SULPHAMETHOXAZOLESuccessful treatment of Pneumocystis carinii and Nocardia asteroides in a renal transplant patientNOCARDIA INFECTIONS IN A GENERAL HOSPITALSensitivity of Nocardia to trimethoprim and sulphonamides in vitroNocardiosis: A reviewOpportunistic infections of the lungsHeavy-Chain Disease 1 February 1967Volume 66, Issue 2Page: 274-284KeywordsLungsNocardiaNocardiosisOpportunistic infectionsPathogensPneumonitisPulmonary diseasesScientistsSteroid therapySurgeons Issue Published: 1 February 1967 PDF downloadLoading ...