The Effect of Pulmonary Emphysema upon Cardiopulmonary Hemodynamics at Rest and During Exercise
Authors: JOHN F. WILLIAMS
Journal: Annals of Internal Medicine (1964)

Article1 May 1964The Effect of Pulmonary Emphysema upon Cardiopulmonary Hemodynamics at Rest and During ExerciseJOHN F. WILLIAMS JR., M.D., ROY H. BEHNKE, M.D., F.A.C.P.JOHN F. WILLIAMS JR., M.D., ROY H. BEHNKE, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-60-5-824 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe aberration in cardiopulmonary hemodynamics occurring in emphysematous subjects at rest is well-known, although there is no clear resolution of the question of the level of the cardiac output. There is much less information concerning the hemodynamics during exercise in such subjects and a paucity of information pertaining to the pulmonary vascular resistance in this disease. The cardiopulmonary hemodynamic data of 53 emphysematous subjects studied at rest and 44 of these subjects studied during exercise are reported in this paper. These data are compared with that of normal subjects and subjects with pulmonary emphysema that have been previously reported in...References1. WILLIAMSWHITEBEHNKE JFDHRH: Cardiopulmonary hemodynamics during exercise in patients with pulmonary emphysema. Amer. J. Cardiol. 10: 46, 1962. CrossrefMedlineGoogle Scholar2. HICKAMFRAYSER JBR: Spectrophotometric determination of blood oxygen. J. Biol. Chem. 180: 457, 1949. CrossrefMedlineGoogle Scholar3. MOUNSEYRITZMANNSILVERSTONEBRISCOEMCLEMORE JPLWNJWAGA: Circulatory changes in severe pulmonary emphysema. Brit. Heart J. 14: 153, 1952. CrossrefMedlineGoogle Scholar4. HARVEYFERRERRICHARDSCOURNAND RMMIDWA: Influence of chronic pulmonary disease on the heart and circulation. Amer. J. Med. 10: 719, 1951. CrossrefMedlineGoogle Scholar5. MCMICHAELSHARPEY-SCHAFER JEP: The action of intravenous digoxin in man. Quart. J. Med. 13: 123, 1944. Google Scholar6. RICHARDS DW: Cardiac output by the catheterization technique in various clinical conditions. 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To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Indianapolis, IndianaFrom the Department of Medicine, Veterans Administration Hospital, and Indiana University School of Medicine, Indianapolis, Indiana.This study was supported in part by grant H4080 and in part with facilities supplied by grant H6380, both from the United States Public Health Service, Bethesda, Maryland, and from the Indiana Heart Association. This work was done during Dr. William's tenure as a Postdoctorate Research Fellow of the American Heart Association.Requests for reprints should be addressed to Roy H. Behnke, M.D., Professor of Medicine, Indiana University School of Medicine, 1100 West Michigan Street, Indianapolis 7, Indiana. 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