Effects of Hypertriglyceridemia on Platelet Counts in Automated Hematologic Analysis
Authors: Osamu Kabutomori
Journal: Annals of Internal Medicine (1999)

Letters2 March 1999Effects of Hypertriglyceridemia on Platelet Counts in Automated Hematologic AnalysisOsamu Kabutomori, BSc, Yoshinori Iwatani, MD, and Miwako Kabutomori, BScOsamu Kabutomori, BScOsaka University Hospital; Osaka 565-0871, Japan (Kabutomori)Osaka University; Osaka 565-0871, Japan (Iwatani)Kawarazaki Hospital; Osaka 567-0036, Japan (Kabutomori), Yoshinori Iwatani, MDOsaka University Hospital; Osaka 565-0871, Japan (Kabutomori)Osaka University; Osaka 565-0871, Japan (Iwatani)Kawarazaki Hospital; Osaka 567-0036, Japan (Kabutomori), and Miwako Kabutomori, BScOsaka University Hospital; Osaka 565-0871, Japan (Kabutomori)Osaka University; Osaka 565-0871, Japan (Iwatani)Kawarazaki Hospital; Osaka 567-0036, Japan (Kabutomori)Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-130-5-199903020-00011 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Levels of chylomicron are increased in the sera of patients with hypertriglyceridemia. Chylomicrons, which contain triglyceride in high concentrations, are usually 0.5 to 1.0 µm in diameter (1). Sometimes, however, they reach a diameter of 1.5 to 3.5 µm, which is equal to the size of a platelet in peripheral blood (2). Therefore, we examined the effect of hypertriglyceridemia on platelet counts measured with two types of automated hematologic analyzers: the NE-8000 (Sysmex, Kobe, Japan), which uses the electrical impedance method, and the THMS-H2 (Bayer, West Haven, Connecticut), which uses the optical method (3).Platelet counts were ...References1. Mead JF, Alfin-Slater RB, Howton DR. Synthesis of lipoproteins.. In: Poják G, eds. Lipids. New York: Plenum; 1986:264-5. Google Scholar2. Flanklin DZ. Platelet morphology and function. In: Williams JW, ed. Hematology. 4th ed. New York: McGraw-Hill; 1990:1172-81. Google Scholar3. Morris MW, Williams WJ, Nelson DA. Automated blood cell counting. In: Beutler E, ed. Hematology. 5th ed. New York: McGraw-Hill; 1995:L3-11. Google Scholar4. Cremer P, Lakomek M, Beck W, Prindull G. The effect of l-asparaginase on lipid metabolism during induction chemotherapy of childhood lymphoblast leukemia. Eur J Pediatr. 1988;147:64-7. CrossrefMedlineGoogle Scholar5. Parsons SK, Skapek SX, Neufeld EJ, Kuhlman K, Young ML, Donnelly M, et al . Asparaginase-associated lipid abnormalities in children with acute lymphoblastic leukemia. Blood. 1997;89:1886-95. CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Osaka University Hospital; Osaka 565-0871, Japan (Kabutomori)Osaka University; Osaka 565-0871, Japan (Iwatani)Kawarazaki Hospital; Osaka 567-0036, Japan (Kabutomori) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPlatelet Counting and Measurement of Platelet DimensionsDetecting Erroneous Blood CountsPlatelet CountingSpurious Counts and Spurious Results on Hematology Analyzers: PlateletsSpurious counts and spurious results on haematology analysers: a review. Part I: platelets 2 March 1999Volume 130, Issue 5Page: 452KeywordsAttentionBloodPlatelets Issue Published: 2 March 1999 Copyright & PermissionsCopyright © 1999 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...