Eradication of Hepatitis C Virus after Interferon-α Therapy
Authors: Tekin Akpolat
Journal: Annals of Internal Medicine (1995)

Letters15 March 1995Eradication of Hepatitis C Virus after Interferon-α TherapyTekin Akpolat, Esin Ozyilkan, and Nurol ArikTekin AkpolatLahey Clinic, Bedford, MA 01805. Ondokuz Mayis University, School of Medicine, Samsun, Turkey 55139. Universita Degli Studi di Milano, 20122 Milan, Italy.Search for more papers by this author, Esin OzyilkanLahey Clinic, Bedford, MA 01805. Ondokuz Mayis University, School of Medicine, Samsun, Turkey 55139. Universita Degli Studi di Milano, 20122 Milan, Italy.Search for more papers by this author, and Nurol ArikLahey Clinic, Bedford, MA 01805. Ondokuz Mayis University, School of Medicine, Samsun, Turkey 55139. Universita Degli Studi di Milano, 20122 Milan, Italy.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-122-6-199503150-00014 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Hepatitis C virus is the most common cause of chronic liver disease in patients receiving hemodialysis, and renal transplantation is contraindicated in patients with chronic active hepatitis and cirrhosis because of the risk for progression of their liver disease.Interferon is the most commonly used treatment for HCV-related chronic hepatitis in patients without uremia. As reported by Romeo and colleagues [2] interferon therapy may lead to complete eradication of virus in some long-term responders. However, these investigators mentioned that patients on hemodialysis cannot receive interferon therapy.Data about the effectiveness of interferon therapy in patients receiving hemodialysis ...References1. Romeo R, Pol S, Berthelot P, Brechot C. Eradication of hepatitis C virus RNA after α-interferon therapy. Ann Intern Med. 1994; 121:276-7. Google Scholar2. Ozyilkan E, Simsek H, Uzunalimoglu B, Telatar H. Interferon treatment of chronic active hepatitis C in patients with end-stage chronic renal failure. Nephron. 1995; (In press). Google Scholar4. Ellis ME, Alfurayh O, Halim MA, Sieck JO, Ali MA, Bernvil SS, et al. Chronic non-A, non-B hepatitis complicated by end-stage renal failure treated with recombinant interferon α. J Hepatol. 1993; 18:210-6. Google Scholar5. Vogel W, Prommegger R, Stummvoll HK, Never U, Grunewald K, Koenig P. Interferon treatment of hepatitis C virus infection in patients on maintenance hemodialysis (Abstract). Hepatology. 1993; 18:91A. Google Scholar6. Espinoza M, Gonzales R, Mata M, Alvarez M, Martin-Malo A, Berdud I, et al. Treatment of chronic hepatitis C in haemodialysis patients with interferon (Abstract). Nephrol Dial Transplant. 1993; 8:967. Google Scholar Author, Article, and Disclosure InformationAffiliations: Lahey Clinic, Bedford, MA 01805. Ondokuz Mayis University, School of Medicine, Samsun, Turkey 55139. Universita Degli Studi di Milano, 20122 Milan, Italy. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 15 March 1995Volume 122, Issue 6Page: 474-475KeywordsChronic hepatitisChronic liver diseaseCirrhosisHepatitis C virusInterferonsLiver diseasesRenal transplantation Issue Published: 15 March 1995 CopyrightCopyright © 1995 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...