Recurrent Spontaneous Hepatic Rupture in Primary Hepatic Amyloidosis
Authors: Chaftik Kacem
Journal: Annals of Internal Medicine (1998)

Letters15 August 1998Recurrent Spontaneous Hepatic Rupture in Primary Hepatic AmyloidosisChaftik Kacem, MD, Kamel Helali, MD, and Francois Puisieux, MDChaftik Kacem, MDCHU Charles Nicolle; Tunis, TunisiaHopital les Bateliers; Lille, France, Kamel Helali, MDCHU Charles Nicolle; Tunis, TunisiaHopital les Bateliers; Lille, France, and Francois Puisieux, MDCHU Charles Nicolle; Tunis, TunisiaHopital les Bateliers; Lille, FranceAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-129-4-199808150-00029 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:We describe a 46-year-old woman who presented with a 2-year history of abdominal discomfort with recurrent extremity ecchymosis and 3 days of increased pain. Upon examination, her abdomen was distended with generalized guarding. Emergency laparotomy revealed hepatomegaly and a massive hemoperitoneum (1500 mL) caused be a partially ruptured subcapsular hematoma (diameter, 15 cm) involving the upper face of the left side of the liver. The hematoma was evacuated, and hemostasis was achieved with local coagulation. Surgical liver biopsy showed portal tracts containing intense amorphous infiltration of hyaline material confirmed to be amyloid by Congo red staining. Immunohistochemical ...References1. Hurd WW, Katholi RE. Acquired functional asplenia: association with spontaneous rupture of the spleen and fatal spontaneous rupture of the liver in amyloidosis. Arch Intern Med. 1980; 140:844-5. Google Scholar2. Okazaki K, Moriyasu F, Shiomura T, Yamamoto T, Suzaki T, Kanematsu Y, et al. Spontaneous rupture of the spleen and liver in amyloidosis-a case report and review of the literature. Gastroenterol Jpn. 1986; 21:518-24. Google Scholar3. Ades CJ, Strutton GM, Walker NI, Furnival CM, Whiting G. Spontaneous rupture of the liver associated with amyloidosis. J Clin Gastroenterol. 1989; 11:85-7. Google Scholar4. Gastineau DA, Gertz MA, Rosen CB, Kyle RA. Computed tomography for diagnosis of hepatic rupture in primary systemic amyloidosis. Am J Hematol. 1991; 37:194-6. Google Scholar5. Harrison RF, Hawkins PN, Roche WR, MacMahon RF, Hubscher SG, Buckels JA. "Fragile" liver and massive hepatic haemorrhage due to hereditary amyloidosis. Gut. 1996; 38:151-2. Google Scholar Author, Article, and Disclosure InformationAuthors: Chaftik Kacem, MD; Kamel Helali, MD; Francois Puisieux, MDAffiliations: CHU Charles Nicolle; Tunis, TunisiaHopital les Bateliers; Lille, France PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySpontaneous hepatic rupture due to primary amyloidosisAmyloid Diseases at the Molecular Level: General Overview and Focus on AL AmyloidosisAmyloid Diseases at the Molecular Level: General Overview and Focus on AL AmyloidosisSpontaneous Intrahepatic Hemorrhage: A Case ReportSpontaneous rupture of the liver in a patient with systemic AL amyloidosis undergoing treatment with high-dose melphalan and autologous stem cell transplantation: A case report with literature reviewAL amyloidosis with spontaneous hepatic rupture: successful treatment by transcatheter hepatic artery embolizationTransient laboratory changes in a cat with repeated hepatic haemorrhages due to amyloidosisHereditary lysozyme amyloidosis: Spontaneous hepatic rupture (15 years apart) in mother and daughter. role of emergency liver transplantationMetabolic storage diseases: amyloidosis 15 August 1998Volume 129, Issue 4Page: 339KeywordsAbdominal painAmyloidosisBiopsyComputed axial tomographyHemorrhageLiverLiver transplantationSpleenStainingSurgery ePublished: 15 August 2000 Issue Published: 15 August 1998 Copyright & PermissionsCopyright © 1998 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...