Diagnostic Performance of Low-Radiation-Dose Coronary Computed Tomography Angiography
Authors: Ali Salavati, Farid Radmanesh
Journal: Annals of Internal Medicine (2011)

Letters16 August 2011Diagnostic Performance of Low-Radiation-Dose Coronary Computed Tomography AngiographyAli Salavati, MD, MPH and Farid Radmanesh, MD, MPHAli Salavati, MD, MPHFrom Zentraklinik, 99437 Bad Berka, Germany, and Tehran University of Medical Sciences, 14155 Tehran, Iran.Search for more papers by this author and Farid Radmanesh, MD, MPHFrom Zentraklinik, 99437 Bad Berka, Germany, and Tehran University of Medical Sciences, 14155 Tehran, Iran.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-155-4-201108160-00024 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:We read von Ballmoos and colleagues' (1) comprehensive systematic review on the diagnostic performance of low-radiation-dose coronary computed tomography angiography with great enthusiasm. However, we have a few concerns about the statistical methods.The authors evaluated between-study heterogeneity by calculating the Cochran Q and I2 statistics. These univariate statistics were primarily developed for meta-analysis of interventional studies (2), and when used in systematic reviews of diagnostic test accuracy (SRDTA), they calculate heterogeneity for sensitivity and specificity separately—that is not accurate enough (3). The I2 statistic is commonly applied with univariate models, such as the Moses-Littenberg method, which ...References1. von Ballmoos MW, Haring B, Juillerat P, Alkadhi H. Meta-analysis: diagnostic performance of low-radiation-dose coronary computed tomography angiography. Ann Intern Med. 2011;154:413-20. [PMID: 21403076] LinkGoogle Scholar2. Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ. 2003;327:557-60. [PMID: 12958120] CrossrefMedlineGoogle Scholar3. Macaskill P, Gatsonis C, Deeks JJ, Harbord RM, Takwoingi Y. Chapter 10: Analyzing and Presenting Results. In: Deeks JJ, Bossuyt PM, Gatsonis C, eds. Cochrane Handbook for Systematic Reviews of Diagnostic Test Accuracy Version 1.0. Birmingham: The Cochrane Collaboration; 2010. Accessed at srdta.cochrane.org/ on 1 March 2011. Google Scholar4. Deeks JJ, Macaskill P, Irwig L. The performance of tests of publication bias and other sample size effects in systematic reviews of diagnostic test accuracy was assessed. J Clin Epidemiol. 2005;58:882-93. [PMID: 16085191] CrossrefMedlineGoogle Scholar5. Salavati A, Radmanesh F, Esfahani SA. Diagnostic accuracy and clinical utility of noninvasive testing for coronary artery disease [Letter]. Ann Intern Med. 2011;154:290: author reply 290. [PMID: 21320946] Google Scholar Author, Article, and Disclosure InformationAffiliations: From Zentraklinik, 99437 Bad Berka, Germany, and Tehran University of Medical Sciences, 14155 Tehran, Iran.Disclosures: None disclosed. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoDiagnostic Accuracy and Clinical Utility of Noninvasive Testing for Coronary Artery Disease Ali Salavati , Farid Radmanesh , and Shadi A. Esfahani Meta-analysis: Diagnostic Performance of Low-Radiation-Dose Coronary Computed Tomography Angiography Moritz Wyler von Ballmoos , Bernhard Haring , Pascal Juillerat , and Hatem Alkadhi Diagnostic Performance of Low-Radiation-Dose Coronary Computed Tomography Angiography Hatem Alkadhi and Moritz Wyler von Ballmoos Metrics Cited ByThe Value of 16-cm Wide-Detector Computed Tomography in Coronary Computed Tomography Angiography for Patients With High Heart Rate VariabilityIdentification of Coronary Artery Orifice to Prevent Coronary Complications in Bioprosthetic and Transcatheter Aortic Valve ReplacementEvidence for prospective ECG-triggering coronary CT angiography in routine practiceDual-source computed tomography angiography for diagnosis and assessment of coronary artery disease: Systematic review and meta-analysis 16 August 2011Volume 155, Issue 4Page: 278KeywordsAngiographyComputed axial tomographyConflicts of interestSpecificityStatistical methodsSystematic reviews ePublished: 16 August 2011 Issue Published: 16 August 2011 CopyrightCopyright © 2011 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...