Minimal Hepatitis C Infectivity in Semen
Authors: Soichiro Terada, Koichi Kawanishi, Katayama Kazuhiko
Journal: Annals of Internal Medicine (1992)

Letters15 July 1992Minimal Hepatitis C Infectivity in SemenSoichiro Terada, MD, Koichi Kawanishi, MD, Katayama Kazuhiko, MDSoichiro Terada, MDSearch for more papers by this author, Koichi Kawanishi, MDSearch for more papers by this author, Katayama Kazuhiko, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-117-2-171_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editors: Both hepatitis B virus and cytomegalovirus are known to be transmitted sexually. To assess the possibility that hepatitis C virus (HCV), a known blood-based infection, could be transmitted by sexual intercourse, samples of serum, semen, and urine were examined for HCV RNA using the polymerase chain reaction.Informed consent was obtained from six men with antibody to HCV (anti-HCV) positivity and chronic hepatitis (mean age, 46.8 ± 11.7 years). They denied homosexual behavior and intravenous drug abuse; half had a history of blood transfusion. Semen samples were obtained after urine samples were collected to prevent contamination...References1. ChomczynskiSacchi PN. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol chloroform extraction. Anal Biochem. 1987;162:156-9. CrossrefMedlineGoogle Scholar2. OkamotoOkadaSugiyamaYotsumotoTanakaYoshizawa HSYSTH. The 5'-terminal sequence of the hepatitis C virus genome. Jpn J Exp Med. 1990;60:167-77. MedlineGoogle Scholar3. SaikiScharfFaloonaMullisHornErlich RSFKGH. Enzymic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia. Science. 1985; 230:1350-4. CrossrefMedlineGoogle Scholar4. EstebanEstebanViladomiuLopez-TolaveraGonzalezHernandez JRLJAJ. Hepatitis C virus antibodies among risk groups in Spain. Lancet. 1989;2:294-7. CrossrefMedlineGoogle Scholar5. HsuWrightLubaMartinFeinstoneGarcia HTDMSG. Failure to detect hepatitis C virus genome in human secretions with the polymerase chain reaction. Hepatology. 1991;14:763-7. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByViral Infections of the Fetus and Neonate, other than RubellaReproductive Assistance for Infected Couples with Bloodborne VirusesTransmission risk of hepatitis C virus via semen during assisted reproduction: how real is it?Risques de l’assistance médicale à la procréation en cas d’infection par le VIH, les virus des hépatites C ou B. Qu’apporte la loi française par l’arrêté de 2001 ?Intermittent detection of hepatitis C virus (HCV) in semen from men with human immunodeficiency virus type 1 (HIV-1) and HCVSperm washing and virus nucleic acid detection to reduce HIV and hepatitis C virus transmission in serodiscordant couples wishing to have childrenRisque viral lié au virus de l’hépatite C en AMPRisque viral en AMPSéroprévalence des hépatites C et B chez les patients infectés par le virus de l'immunodéficience humaine en milieu psychiatriqueHCV transmission in family members of subjects with HCV related chronic liver diseaseEpidémiologie du virus de l'hépatite CThe Sexual Transmission of Hepatitis C VirusViral hepatitisHepatitis C: progress and problemsThe low risk of hepatitis C virus transmission among sexual partners of confirmed HCV-positive blood donorsDemonstration of hepatitis C virus genome in saliva and urine of patients with type C hepatitis: Usefulness of the single round polymerase chain reaction method for detection of the HCV genomeSexual transmission of hepatitis C virus 15 July 1992Volume 117, Issue 2Page: 171-172KeywordsHepatitis AHepatitis B virusHepatitis CHepatitis C virusHomosexualsInfectious hepatitisPolymerase chain reactionRNASemenUrine Issue Published: 15 July 1992 PDF DownloadLoading ...