tbuckley/cabot-search huggingface dataset:
Correction: Hiccups and Achalasia
Authors: Howard Seeman
Journal: Annals of Internal Medicine (1991)

Letters15 December 1991Correction: Hiccups and AchalasiaHoward Seeman, MDHoward Seeman, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-115-12-986 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe opening sentence of the Results of a recent Brief Report (1) appeared incorrectly. The sentence should read: Patients with achalasia ranged in age from 13 to 80 years (mean, 47 years); control patients ranged in age from 33 to 82 years (mean, 53 years) (P> 0.2)....Reference1. Seeman H and Traube M. Hiccups and achalasia. Ann Intern Med. 1991;115:711-2. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: Howard Seeman, MDAffiliations: Tanner Medical Center Carrollton, GA 30117 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 15 December 1991Volume 115, Issue 12Page: 986-986 ePublished: 1 December 2008 Issue Published: 15 December 1991 PDF downloadLoading ...
Inferior Vena Caval Obstruction Secondary to Retroperitoneal Fibrosis Causing Abnormal Venous Return of Left Lower Limb to Portal Circulation
Authors: HUSSEIN M. ABDEL???DAYEM, C V MATHEW, ALI SAHWEIL, MOHAMMED EL???SAYED
Journal: Clinical Nuclear Medicine (1984)

ABDEL–DAYEM, HUSSEIN M. M.D.*; MATHEW, C V M.D.†; SAHWEIL, ALI M.D.‡; EL–SAYED, MOHAMMED B.Sc.‡ Author Information
Detection of Staphylococcus Aureus by Real-Time PCR in Chronic Rhinosinusitis with Nasal Polyps
Authors: A. Tripathi, B. Tancowny, Q. Truong-Tran, S. Retsema, R. Kern, D. Conley, L. Suh, R. Schleimer, L. Grammer
Journal: Journal of Allergy and Clinical Immunology (2006)
Physicians in Art
Authors: Sidney C. Wiggin
Journal: New England Journal of Medicine (1952)

THE physician has within him the qualities of the artist — the nature that led him into the study of medicine and his training in observation and appreciation of the human being. In his art, the physician derives complete relaxation from tension and from the cares of medicine. He learns to "work by the side of work." It is a hobby that gives lasting renewal of energy and spirit. The results of his energies expended in his art go out to the many who appreciate the beauties of nature and help them to forget the drudgeries of daily life. And, . . .
Gender and Psychopathology
Authors: Sara C. Charles
Journal: JAMA (1996)

This book was originally intended to examine systematically and critically gender effects on the epidemiology, expression of symptoms, age at onset, sequelae, differential diagnosis, and treatment response of the major psychiatric diagnostic entities. "The original project," in the words of the editor, "proved to be unrealistic." Although less ambitious, the present volume is a worthy contribution to a complex and important subject. The initial chapter, "Gender, Development, and Psychopathology," by psychiatrists Malkah Notman and Carol Nadelson, establishes the definitions and sets the tone. The authors define gender identity as the "internalized sense of maleness or femaleness and the knowledge of one's biological sex, including the associated psychological attributes." Gender role, the "expectations, attitudes, and behaviors that are considered appropriate for each gender" in a particular culture, is noted as only one of the many diverse and complex factors that contribute to one's sense of gender identity. Although the etiology of
Blue Plans Medical Necessity Program
Authors: Marvin J. Shapiro
Journal: JAMA (1979)

ADOLPH et al (JAMA 241:799-800,1979), in their COMMENTARY, protest the policy of the Blue Cross and Blue Shield associations as it applies to phonocardiography, pulse tracings, and apex cardiograms. The writers fear that patients will be denied these procedures when they might be of specific benefit to the patient. The policy they protest denies nothing. It recommends to Blue Cross and Blue Shield plans that payment be made only when the claim is accompanied by a report from the physician stating the indications in the given case. There is nothing in the policy that recommends abandonment of phonocardiography, as implied in the title, and nothing that denies any of the procedures when indicated. Nine of the 11 cardiologists protesting the policy might protest the need to submit a claim by report, but there is no justification for the implication that the policy recommended to the associations by the American College
Neonatal Osteomyelitis Caused by Group B Streptococci
Authors: Jata S. Ghosh
Journal: JAMA (1978)

To the Editor.—  McGuire and his colleagues (238:2054, 1977) are indeed correct that osteomyelitis caused by group B β-hemolytic streptococci (GBS) is rare. However, their assertion that there are only five reported cases of osteomyelitis from GBS in neonates is erroneous. There are three additional neonatal cases of osteomyelitis caused by GBS. 1-3 In one of these three cases, 1 GBS were also isolated from vaginal smears of the mother, whereas in the remaining two instances 2-3 GBS were not found in vaginal-cervical smears or in breast milk from the mothers five to six weeks after delivery.
Bruxism Related to Levodopa Therapy
Authors: Kenneth R. Magee
Journal: JAMA (1970)

To the Editor.—  During the investigation phase of levodopa (L-Dopa) therapy for Parkinson's disease, clinicians have reported a wide range of side effects. Fortunately most are not serious; however, several are difficult to control without nullifying the dose or the effectiveness of the drug. In many instances, such as the case reported here, the physician faces the challenge of detecting and managing side effects.  The abnormal involuntary movements that result from levodopa therapy frequently appear in the face, lips, and tongue and are often termed mouthing movements. Movements of the extremities may resemble chorea or athetosis. Forced hyperventilation, neck jerking, or slow arm or leg movements that are not actually choreal or athetosic still do not fit into other common classifications of abnormal movements. These signs are a limiting factor in dosage, and as they develop, the physician must weigh their severity against the patient's relief from the symptoms of
Three-base deletion mutation c.120_122delGTT in<i>ATP2A2</i>leads to the unique phenotype of comedonal Darier disease
Authors: D. Tsuruta, M. Akiyama, A. Ishida-Yamamoto, H. Imanishi, N. Mizuno, J. Sowa, H. Kobayashi, M. Ishii, I. Kurokawa, H. Shimizu
Journal: British Journal of Dermatology (2009)

Conflicts of interest: none declared. The first two authors contributed equally to this work. Darier disease (DD; Darier–White disease; OMIM 124200) is an autosomal dominant inherited disorder.1 Clinically, it is characterized by recurrent and multiple hyperkeratotic papules or nodules affecting the trunk and flexural aspects of the extremities.1 Characteristic histopathological features are dyskeratotic cells in the form of corps ronds and grains, suprabasal acantholysis forming suprabasal lacunae and irregular upward proliferation into the lacunae of papillae lined with a single layer of basal cells, the so‐called villi.2 The causative gene is ATP2A2 (OMIM 108740) on chromosome 12, which encodes the sarco/endoplasmic reticulum calcium pump ATPase (SERCA2).2 Clinical variants include the hypertrophic, vesiculobullous, hypopigmented, cornifying, zosteriform and linear subtypes, and the rare subtype comedonal Darier disease (CDD).1, 3–6 CDD tends to appear in seborrhoeic areas. The characteristic morphological features are prominent follicular involvement, sometimes associated with keratotic plugs, and the presence of greatly elongated dermal villi and papillary projections.4 There have been no conclusive reports on the aetiology of CDD and it is still controversial as to whether or not CDD is a variant of DD, and if it is caused by ATP2A2 gene mutations, although a combination of CDD and classic DD was reported in one patient.7 The present study identifies a previously unreported three‐base deletion mutation in ATP2A2 in a patient with CDD.
The SF36 health survey questionnaire: an outcome measure suitable for routine use within the NHS?
Authors: A M Garratt, D A Ruta, M I Abdalla, J K Buckingham, I T Russell
Journal: BMJ (1993)

OBJECTIVE--To assess the validity, reliability, and acceptability of the short form 36 (SF 36) health survey questionnaire (a shortened version of a battery of 149 health status questions) as a measure of patient outcome in a broad sample of patients suffering from four common clinical conditions. DESIGN--Postal questionnaire, followed up by two reminders at two week intervals. SETTING--Clinics and four training practices in north east Scotland. SUBJECTS--Over 1700 patients aged 16-86 with one of four conditions--low back pain, menorrhagia, suspected peptic ulcer, or varicose veins--and a comparison sample of 900 members of the general population. MAIN OUTCOME MEASURES--The eight scales within the SF36 health profile. RESULTS--The response rate exceeded 75% in the patient population (1310 respondents). The SF36 satisfied rigorous psychometric criteria for validity and internal consistency. Clinical validity was shown by the distinctive profiles generated for each condition, each of which differed from that in the general population in a predictable manner. Furthermore, SF36 scores were lower in referred patients than in patients not referred and were closely related to general practitioners9 perceptions of severity. CONCLUSIONS--These results provide support for the SF36 as a potential measure of patient outcome within the NHS. The SF36 seems acceptable to patients, internally consistent, and a valid measure of the health status of a wide range of patients. Before it can be used in the new health service, however, its sensitivity to changes in health status over time must also be tested.
Differences in phototoxic potency should be considered when tetracyclines are prescribed during summer-time. A study on doxycycline and lymecycline in human volunteers, using an objective method for recording erythema
Authors: M. BJELLERUP, B. LJUNGGREN
Journal: British Journal of Dermatology (1994)

In order to test the phototoxic potency of the two tetracyclines most frequently prescribed in Sweden, a double-blind cross-over study using a double-dummy technique with doxycycline 0.1 g twice daily, lymecycline 0.6 g twice daily, and placebo, was performed in 15 healthy volunteers. Drugs were given for 3 consecutive days, and on the third day volunteers were tested with 25, 50, 75 and 100 J/cm2 of artificial long-wave ultraviolet radiation (UVA), and assessed 6 h later for erythematous photoreactions. Objective readings were made using skin reflectance spectrophotometry. All three substances were tested in each individual at weekly intervals. Within 50, 75 and 100 J/cm2 of UVA, lymecycline showed a slight increase in erythema compared with placebo, but this was not significant (50 and 100 J/cm2), or was of low significance (75 J/cm2). However, with the same doses, doxycycline showed a substantial increase in erythema compared with placebo, which was highly significant. We conclude that doxycycline has a higher phototoxic potency than lymecycline, and this is in agreement with earlier in vitro experimental data. We recommend that therapy with doxycycline is avoided during summer-time, and during holidays in a sunny climate.
AN IMPROVED PROCEDURE FOR THE STAINING OF ACID-FAST ORGANISMS IN TISSUE
Authors: BENJAMIN H. HAGER
Journal: JAMA (1923)

Investigators familiar with the demonstration of the bacilli of tuberculosis in tissue are aware of the difficulties attending the customary procedure of section staining, particularly in retaining the counterstain as the tissue is passed through the various dehydrating preparations, or resulting from the failure thoroughly to dehydrate the stained tissue by omitting those dehydrating solutions which attack the counterstain. Satisfactory results are even more uncertain in frozen sections than in sections embedded in paraffin or celloidin. The method described here affords a rapid and simple technic for demonstration of<i>Bacillus leprae</i>and<i>Bacillus tuberculosis</i>in tissues. Excellent results are also obtained in paraffin sections. <h3>TECHNIC</h3> Fresh tissue, having been hardened in a 10 per cent. dilution of liquor formaldehydi for at least fifteen hours, is frozen and sectioned. The thinner the section, the more satisfactory is the stain, and the finding of the organism is likewise facilitated. The cut sections
Intraoperative and Perioperative Morbidity of Contemporary Radical Retropubic Prostatectomy in a Consecutive Series of 1243 Patients: Results of a Single Center between 1999 and 2002
Authors: Herbert Augustin, Peter Hammerer, Markus Graefen, Jüri Palisaar, Joachim Noldus, Salvador Fernandez, Hartwig Huland
Journal: European Urology (2003)
The Neuroses of the Genito-Urinary System in the Male; with Sterility and Impotence.
Authors: Robert Ultzmann
Journal: JAMA (1890)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
T-independent and T-dependent B lymphoblasts: helper T cells prime for interleukin 2-induced growth and secretion of immunoglobulins that utilize downstream heavy chains.
Authors: M S Forman, E Puré
Journal: The Journal of Experimental Medicine (1991)

Resting B cells enlarge, enter the cell cycle, and change their surface phenotype when activated via the surface immunoglobulin (Ig) receptor, but subsequent cell growth and antibody production is relatively limited. To identify stimuli that might prime B cells for enhanced function in vitro, we have compared the effects of anti-Ig with helper T (Th) cells on the formation of B lymphoblasts and the subsequent ability of the blasts to grow and secrete Ig. The B blasts first were induced by either anti-Ig, anti-Ig plus T cell-derived lymphokines, or alloreactive T blasts. Each population of B blasts showed enhanced expression of cell surface adhesion molecules, interleukin 2 receptor (IL-2R) p55, and MHC products, as well as decreased expression of IgD. The allo-activated B blasts were distinctive in expressing low levels of Thy-1 and increased reactivity with peanut agglutinin, a marker of germinal center B blasts in situ. The function of the different populations of B blasts was also different. Whereas anti-Ig or anti-Ig plus lymphokines primed for enhanced responses to lipopolysaccharide (LPS), the B blasts induced by Th cells were insensitive to LPS. B lymphoblasts that had been activated in the presence of helper factors or Th cells responded vigorously to recombinant IL-2 with growth and Ig secretion, and this response was enhanced in the presence of anti-Ig. The B blasts activated directly by Th cells, but not by anti-Ig plus lymphokines, were primed to secrete high levels of IgG1 and IgA. Therefore, the phenotype and function of a B lymphoblast depends upon the manner in which it is primed. When primed by Th cells, IL-2 proves to be the predominant mediator of clonal expansion and antibody secretion.
Cell-mediated Immunity to Human Tamm-Horsfall Glycoprotein in Autoimmune Liver Disease with Renal Tubular Acidosis
Authors: D. C. Tsantoulas, I. G. McFarlane, B. Portmann, A. L. W. F. Eddleston, R. Williams
Journal: BMJ (1974)

Cell-mediated immune responses to Tamm-Horsfall glycoprotein isolated from human urine were investigated using the leucocyte migration test. Abnormal responses were found in 91% of patients with active chronic hepatitis or primary biliary cirrhosis with an associated renal tubular acidosis (R.T.A.) but in only 19% of those without R.T.A. In nearly all of a group of patients without autoimmune liver disease and in a control group of normal subjects results were within normal limits. In addition, using an immunofluorescent technique with rabbit antibody to human Tamm-Horsfall glycoprotein, it was possible to show the presence in human liver cell membrane of material reacting immunologically as Tamm-Horsfall. These findings suggest that the development of an immune response to this glycoprotein, initiated by release of cross-reacting antigens from damaged hepatocytes, could be the mechanism underlying the occurrence of R.T.A. in some patients with autoimmune liver disease.
Isolating patients in hospital to control infection. Part III--Design and construction of isolation accommodation.
Authors: K D Bagshawe, R Blowers, O M Lidwell
Journal: BMJ (1978)

arrive tired and wish to sign on with minimum fuss.To avoid queues at the registration booths, all queries should be referred to the secretariat.Any delegate who is unable to produce a congress registration card should be escorted personally to the secretariat, where the problem should be resolved.The common cause of a problem is usually a lost card (in which case a duplicate may be issued), or perhaps registration fees have been paid late, in which case no card would have been issued.It is not unusual for delegates from Eastern Europe to prefer to pay on arrival.Queries may also arise over tickets for the various social events and here you reap the benefit of being able to produce, from the same plastic envelope as the record card, the delegate's original ticket application form.A cashier is essential in the registration area to handle registrations, including day registrations and ticket payments.Life is much simpler if only one person handles cash and if they have proper facilities.Throughout the conference, and especially during peak registration times, members of the local organising committee should be constantly on hand to deal with contingencies and also to introduce themselves to any delegate who looks lost.The impression this gives, and justifiably so, of looking after your delegates, greatly helps the success of the entire project. Hospital TopicsIsolating patients in hospital to control infection* Part III-Design and construction of isolation accommodation K D BAGSHAWE, R BLOWERS, 0 M LIDWELL British Medical J7ournal, 1978, 2, 744-748 Good isolation practice is easier in a well-designed building.Easy, direct, and short-distance access to patients, supplies, and facilities lightens the nursing load, thereby giving more time for the proper observance of isolation procedures.There is, however, a potential conflict between the advantages of compact planning and the increased possibilities that this affords for transfer of micro-organisms between patients, by contact and airborne routes.Segregation of patients from each other and separation of clean from potentially contaminated materials is of first importance in creating an effective isolation complex.Reconciling these factors in a practical way is the problem of isolation-unit designs. RemotenessIt is common experience that infection with particular strains of micro-organisms may be widespread in one ward of a hospital but spread only slowly, if at all, to other ward units.Several factors might be implicated.There will be different nursing and probably domestic staff for each ward, although auxiliary and,
The Bedside Evaluation: Ritual and Reason
Authors: Abraham Verghese, Erika Brady, Cari Costanzo Kapur, Ralph I. Horwitz
Journal: Annals of Internal Medicine (2011)

The bedside evaluation, consisting of the history and physical examination, was once the primary means of diagnosis and clinical monitoring. The recent explosion of imaging and laboratory testing has inverted the diagnostic paradigm. Physicians often bypass the bedside evaluation for immediate testing and therefore encounter an image of the patient before seeing the patient in the flesh. In addition to risking delayed or missed diagnosis of readily recognizable disease, physicians who forgo or circumvent the bedside evaluation risk the loss of an important ritual that can enhance the physician-patient relationship. Patients expect that some form of bedside evaluation will take place when they visit a physician. When physicians complete this evaluation in an expert manner, it can have a salutary effect. If done poorly or not at all, in contrast, it can undermine the physician-patient relationship. Studies suggest that the context, locale, and quality of the bedside evaluation are associated with neurobiological changes in the patient. Recognizing the importance of the bedside evaluation as a healing ritual and a powerful diagnostic tool when paired with judicious use of technology could be a stimulus for the recovery of an ebbing skill set among physicians.
Health Literacy and Outcomes Among Patients With Heart Failure
Authors: Pamela N. Peterson
Journal: JAMA (2011)

ContextLittle is known about the effects of low health literacy among patients with heart failure, a condition that requires self-management and frequent interactions with the health care system.Objective To evaluate the association between low health literacy and all-cause mortality and hospitalization among outpatients with heart failure.Design, Setting, and Patients Retrospective cohort study conducted at Kaiser Permanente Colorado, an integrated managed care organization.Outpatients with heart failure were identified between January 2001 and May 2008, were surveyed by mail, and underwent follow-up for a median of 1.2 years.Health literacy was assessed using 3 established screening questions and categorized as adequate or low.Responders were excluded if they did not complete at least 1 health literacy question or if they did not have at least 1 year of enrollment prior to the survey date. Main Outcome MeasuresAll-cause mortality and all-cause hospitalization. ResultsOf the 2156 patients surveyed, 1547 responded (72% response rate).Of 1494 included responders, 262 (17.5%) had low health literacy.Patients with low health literacy were older, of lower socioeconomic status, less likely to have at least a high school education, and had higher rates of coexisting illnesses.In multivariable Cox regression, low health literacy was independently associated with higher mortality (unadjusted rate, 17.6% vs 6.3%; adjusted hazard ratio, 1.97 [95% confidence interval, 1.3-2.97];P=.001) but not hospitalization (unadjusted rate, 30.5% vs 23.2%; adjusted hazard ratio, 1.05 [95% confidence interval, 0.8-1.37];P=.73). ConclusionAmong patients with heart failure in an integrated managed care organization, low health literacy was significantly associated with higher all-cause mortality.