Pernicious Anemia and Colorectal Cancer
Authors: Murthy S. Badiga
Journal: Annals of Internal Medicine (1990)

Letters and Corrections15 April 1990Pernicious Anemia and Colorectal CancerMurthy S. Badiga, MD, Nagarjuna Yerra, MD, Joseph M. Navone, MDMurthy S. Badiga, MDSearch for more papers by this author, Nagarjuna Yerra, MDSearch for more papers by this author, Joseph M. Navone, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-112-8-630_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editor: Disappointingly, the diagnostic criteria for pernicious anemia used in the study by Talley and colleagues (1) were less stringent than those used in other studies. Any patient with anemia characterized by vitamin B12 deficiency due to such diverse causes as improper nutrition, malabsorption syndromes including intestinal disease and resection, bacterial overgrowth, and pancreatitis would have met the requirements and could have been erroneously included in the study as having pernicious anemia.The authors mentioned that "a portion" of the study period antedated the specific tests currently available for diagnosing pernicious anemia. This being the case, was there...References1. Talley N, Chute C, Larson D, Epstein R, Lydick E, and Melton L. Risk for colorectal adenocarcinoma in pernicious anemia, a population-based cohort study. Ann Intern Med. 1989;111:738-42. LinkGoogle Scholar2. Thiruvengadam R, Hench V, Melton L, and DiMagno E. Cancer of the nongastric hollow organs of the gastrointestinal tract after gastric surgery. Arch Intern Med. 1988;148:405-7. CrossrefMedlineGoogle Scholar3. Elsborg L and Mosbech J. Pernicious anaemia as a risk factor in gastric cancer. Acta Med Scand. 1979;206:315-8. CrossrefMedlineGoogle Scholar1. Talley N, Chute C, Larson D, Epstein R, Lydick E, and Melton L. Risk for colorectal adenocarcinomas in pernicious anemia. Ann Intern Med. 1989;111:738-42. LinkGoogle Scholar2. : Omeprazole meeting. Federal Register. 1989 Feb 2:8240. Google Scholar1. Lindenbaum J. Status of laboratory testing in the diagnosis of megaloblastic anemia. Blood. 1983;61:624-7. CrossrefMedlineGoogle Scholar2. Talley N. Chronic (nonerosive) gastritis: pathogenesis and management. Dig Dis. 1989;7:61-75. CrossrefMedlineGoogle Scholar3. Schafer L, Larson D, Melton L, Higgins J, and Zinsmeister A. Risk of development of gastric carcinoma in patients with pernicious anemia: a population based study in Rochester, Minnesota. Mayo Clin Proc. 1985;60:444-8. CrossrefMedlineGoogle Scholar4. Foster H, Tuis J, and Lamers C. The effect of oral omeprazole on serum gastrin and serum pepsinogen I levels. Gastroenterology. 1984;87:1030-4. CrossrefMedlineGoogle Scholar5. Brinton L, Gridley G, Hrubec Z, Hoover R, and Fraumeri J. Cancer risk following pernicious anemia. Br J Cancer. 1989;59:810-3. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: Murthy S. Badiga, MD; Nagarjuna Yerra, MD; Joseph M. Navone, MDAffiliations: Our Lady of Mercy Medical Center Bronx, NY 10466 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 15 April 1990Volume 112, Issue 8Page: 630-631KeywordsBacterial diseasesColorectal cancerNutritionPancreatitisPernicious anemiaVitamin B12 deficiency ePublished: 1 December 2008 Issue Published: 15 April 1990 PDF downloadLoading ...