CD4 Counts and HIV-related Deaths
Authors: Wheaton Williams, Joseph J. Drabick, Douglas B. Tang
Journal: Annals of Internal Medicine (1992)

Letters15 January 1992CD4 Counts and HIV-related DeathsWheaton Williams, MD, Joseph J. Drabick, MD, Douglas B. Tang, PhDWheaton Williams, MDSearch for more papers by this author, Joseph J. Drabick, MDSearch for more papers by this author, Douglas B. Tang, PhDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-116-2-168 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editors: In their recent paper, Yarchoan and colleagues (1) observed that most deaths among patients with the acquired immunodeficiency syndrome (AIDS) or AIDS-related complex (ARC) receiving zidovudine, occurred in those with fewer than 50 CD4 cells/mm3.We recently reviewed the outpatient records of HIV-infected patients who were treated at the Walter Reed Army Medical Center and who died between July 1985 and July 1991 to determine whether the rate of decrease in CD4 counts is a patient-specific factor related to individual survival (2). Of the 172 deceased patients infected with human immunodeficiency virus (HIV) initially identified, 40 cases...References1. YarchoanVenzonPludaLietzauWyvillTsiatis RDJJKA. CD4 count and the risk for death in patients infected with HIV receiving antiretroviral therapy. Ann Intern Med. 1991; 115: 184-9. LinkGoogle Scholar2. DrabickWilliamsSunTangChung JWWDR. A mathematical analysis of CD4-lymphocyte decline in HIV-infected patients. [Abstract # 1388]. 31st Interscience Conference on Antimicrobial Agents and Chemotherapy, 29 September to 2 October 1991, Chicago, Illinois. Google Scholar3. MooreHidalgoSuglandChaisson RJBR. Zidovudine and the natural history of the acquired immunodeficiency syndrome. N Engl J Med. 1991;324:1412-6. CrossrefMedlineGoogle Scholar1. YarchoanVenzonPludaLietzauWyvillTsiatis RDJJKA. CD4 count and the risk for death in patients infected with HIV receiving antiretroviral therapy. Ann Intern Med. 1991 ;115: 184-9. LinkGoogle Scholar1. YarchoanVenzonPludaLietzauWyvillTsiatis RDJJKA. CD4 count and the risk for death in patients infected with HIV receiving antiretroviral therapy. Ann Intern Med. 1991;115: 184-9. LinkGoogle Scholar2. Horsburgh C. Mycobacterium avium complex infection in the acquired immunodeficiency syndrome. N Engl J Med. 1991;324: 1332-8. CrossrefMedlineGoogle Scholar3. . Opportunistic non-Hodgkin's lymphomas among severely immunocompromised HIV-infected patients surviving for prolonged periods on antiretroviral therapy—United States. MMWR. 1991;40:591-600. MedlineGoogle Scholar4. FeichtingerPutkonenParraviciniLiKaayaBottiger HPCSED. Malignant lymphomas in cynomolgus monkeys infected with simian immunodeficiency virus. Am J Pathol. 1990;137:1311-5. MedlineGoogle Scholar5. YarchoanPludaThomasMitsuyaBrouwersWyvill RJRHPK. Long-term toxicity/activity profile of 2′,3′-dideoxyinosine in AIDS or AIDS-related complex. Lancet. 1990;2:526-9. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: Wheaton Williams, MD; Joseph J. Drabick, MD; Douglas B. Tang, PhD PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe natural history of HIV infection: A study in Edinburgh drug usersHIV Disease: Current ConceptsCD4 Lymphocyte Decline and Survival in Human Immunodeficiency Virus InfectionAIDS Aware 15 January 1992Volume 116, Issue 2Page: 168-170KeywordsAIDSAIDS related complexHIVOutpatients ePublished: 1 December 2008 Issue Published: 15 January 1992 PDF downloadLoading ...