Oral Montelukast versus Inhaled Salmeterol To Prevent Exercise-Induced Bronchoconstriction
Authors: Anthony J. Grieco
Journal: Annals of Internal Medicine (2000)

Letters5 September 2000Oral Montelukast versus Inhaled Salmeterol To Prevent Exercise-Induced BronchoconstrictionAnthony J. Grieco, MD and Jessica Burstein-Stein, BSAnthony J. Grieco, MDNew York University School of Medicine; New York, NY 10016 (Grieco, Burstein-Stein)Search for more papers by this author and Jessica Burstein-Stein, BSNew York University School of Medicine; New York, NY 10016 (Grieco, Burstein-Stein)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-133-5-200009050-00019 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:The report (1) of efficacy of a leukotriene receptor antagonist for asthma prompts our report of zafirlukast-associated hepatitis. A 68-year-old woman had had asthma for 25 years. She required intermittent corticosteroid therapy and had never been hospitalized for asthma; her condition was generally controlled with albuterol and inhaled corticosteroids. The patient experienced increased asthma severity, and zafirlukast was added. Her asthma improved, and she received maintenance therapy with zafirlukast until jaundice developed. After 4 months of zafirlukast therapy, she developed weakness and anorexia, followed by jaundice, dark urine and light-colored stools, and nausea and right upper quadrant ...Reference1. Edelman JM, Turpin JA, Bronsky EA, Grossman J, Kemp JP, Ghannam AF, et al . Oral montelukast compared with inhaled salmeterol to prevent exercise-induced bronchoconstriction. A randomized, double-blind trial. Exercise Study Group. Ann Intern Med. 2000;132:97-104. LinkGoogle Scholar Author, Article, and Disclosure InformationAuthors: Anthony J. Grieco, MD; Jessica Burstein-Stein, BSAffiliations: New York University School of Medicine; New York, NY 10016 (Grieco, Burstein-Stein) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoOral Montelukast Compared with Inhaled Salmeterol To Prevent Exercise-Induced Bronchoconstriction Jonathan M. Edelman , Jennifer A. Turpin , Edwin A. Bronsky , Jay Grossman , James P. Kemp , Asma F. Ghannam , Paul T. DeLucca , Glenn J. Gormley , and David S. Pearlman , for the Exercise Study Group*Oral Montelukast versus Inhaled Salmeterol To Prevent Exercise-Induced Bronchoconstriction Eric P. Brestel Oral Montelukast versus Inhaled Salmeterol To Prevent Exercise-Induced Bronchoconstriction Jonathan M. Edelman Montelukast-Induced Hepatitis Marc F. Goldstein , James Anoia , and Martin Black Metrics Cited byMontelukast-Induced HepatitisMarc F. Goldstein, MD, James Anoia, MD, and Martin Black, MDLeukotriene antagonistsA Case of Montelukast-Induced HepatotoxicityDrug-induced liver diseaseZafirlukast 5 September 2000Volume 133, Issue 5Page: 392KeywordsAsthmaLeukotrieneLiverReceptor antagonist therapySerum glutamic oxaloacetic transaminaseSplenomegalyTemperatureUltrasound imagingUrineWine ePublished: 5 September 2000 Issue Published: 5 September 2000 Copyright & PermissionsCopyright © 2000 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...