Nosocomial Klebsiella Infections: Intestinal Colonization as a Reservoir
Authors: RICHARD SELDEN
Journal: Annals of Internal Medicine (1971)

Article1 May 1971Nosocomial Klebsiella Infections: Intestinal Colonization as a ReservoirRICHARD SELDEN, M.D., SHARON LEE, B.A., WEN LAN LOU WANG, PH.D., JOHN V. BENNETT, M.D., THEODORE C. EICKHOFF, M.D.RICHARD SELDEN, M.D., SHARON LEE, B.A., WEN LAN LOU WANG, PH.D., JOHN V. BENNETT, M.D., THEODORE C. EICKHOFF, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-74-5-657 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptA prospective study of patients admitted to a hospital where there was endemic nosocomial infection with multidrug-resistant klebsiella was undertaken to evaluate the role of intestinal colonization of patients. Among 31 patients who became intestinal carriers of klebsiella during hospitalization, 14 subsequently became infected by the same serotype. Of 101 patients who did not become intestinal carriers of klebsiella, only 11 were infected by that organism. Antibiotic therapy was shown to be predisposing to intestinal colonization with klebsiella and to exert a selective pressure in favor of multidrug-resistant klebsiella. Gastrointestinal acquisition and carriage of klebsiella by patients may be an...References1. Green for danger (leading article). Lancet 2:352-353, 1961 MedlineGoogle Scholar2. FINLANDJONESBARNES MWM: Occurrence of serious bacterial infections since the introduction of antimicrobial agents. JAMA 170:2188-2197, 1959 CrossrefMedlineGoogle Scholar3. ROGERS D: The changing pattern of life-threatening infections. New Eng J Med 261:677-683, 1959 CrossrefMedlineGoogle Scholar4. STEINHAUEREICKHOFFKISLAK BTJ: The klebsiella-enterobacter-serratia division: clinical and epidemiologic characteristics. Ann Intern Med 65:1180-1194, 1966 LinkGoogle Scholar5. MERTZSCHARERMCCLEMENT JLJ: A hospital outbreak of klebsiella pneumonia from inhalation therapy with contaminated aerosol solutions. 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WIERNIK, M.D.Hospital infectionsFACTORS INFLUENCING COLONISATION AND ANTIBIOTIC-RESISTANCE PATTERNS OF GRAM-NEGATIVE BACTERIA IN HOSPITAL PATIENTSA Klebsiella Outbreak in a Pediatric NurseryIatrogenic urosepsisInfectious diseases: annual review of significant publications.Continued Surveillance of Serratia marcescens Infections by Bacteriocin Typing: Investigation of Two Outbreaks of Cross-Infection in an Intensive Care UnitIntestinal Microflora in Patients with Alcoholic Cirrhosis: Urea-Splitting Bacteria and Neomycin ResistanceBacteroides, Other Nosocomial Bacteria, and AntibioticsPETER C. FUCHS, M.D.Epidemiology of Klebsiella Infections 1 May 1971Volume 74, Issue 5Page: 657-664KeywordsBacterial diseasesHospital medicineHospitalizationsInfectious disease controlKlebsiellaMedical educationMultidrug resistanceNosocomial infectionsProspective studiesVeteran care Issue Published: 1 May 1971 PDF downloadLoading ...