Should Patients With Stroke Wear Compression Stockings?
Authors: Clive Kearon, Martin O'Donnell
Journal: Annals of Internal Medicine (2011)

Letters5 April 2011Should Patients With Stroke Wear Compression Stockings?Clive Kearon, MB, PhD and Martin O'Donnell, MB, PhDClive Kearon, MB, PhDFrom McMaster University, Hamilton, Ontario L8S 4L8, Canada; and HRB Clinical Research Facility, National University of Ireland, Galway, Galway, Ireland. and Martin O'Donnell, MB, PhDFrom McMaster University, Hamilton, Ontario L8S 4L8, Canada; and HRB Clinical Research Facility, National University of Ireland, Galway, Galway, Ireland.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-154-7-201104050-00016 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:Dr. Sprigg and colleagues note that they "do not believe that low-dose heparin should be used routinely for the prevention of VTE in most patients with stroke." We agree that low-dose heparin should not be used routinely in patients with ischemic stroke and did not make such a suggestion (1). As Dr. Sprigg and colleagues also note, "Prophylactic low-dose anticoagulation may help to treat patients at high risk for VTE in whom the risk for VTE is likely to outweigh the risk for SICH."If CLOTS (Clots in Legs Or sTtockings after Stroke) Trial 1 (2) had found ...References1. O'Donnell M, Kearon C. Thromboembolism prevention in ischaemic stroke. Lancet. 2007;369:1413-5. [PMID: 17467497] CrossrefMedlineGoogle Scholar2. Dennis M, Sandercock PA, Reid J, Graham C, Murray G, Venables G, et al; CLOTS Trials Collaboration. Effectiveness of thigh-length graduated compression stockings to reduce the risk of deep vein thrombosis after stroke (CLOTS trial 1): a multicentre, randomised controlled trial. Lancet. 2009;373:1958-65. [PMID: 19477503] CrossrefMedlineGoogle Scholar3. The International Stroke Trial (IST): a randomised trial of aspirin, subcutaneous heparin, both, or neither among 19435 patients with acute ischaemic stroke. International Stroke Trial Collaborative Group. Lancet. 1997;349:1569-81. [PMID: 9174558] Google Scholar4. Bath PM, Lindenstrom E, Boysen G, De Deyn P, Friis P, Leys D, et al. Tinzaparin in acute ischaemic stroke (TAIST): a randomised aspirin-controlled trial. Lancet. 2001;358:702-10. [PMID: 11551576] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Clive Kearon, MB, PhD; Martin O'Donnell, MB, PhDAffiliations: From McMaster University, Hamilton, Ontario L8S 4L8, Canada; and HRB Clinical Research Facility, National University of Ireland, Galway, Galway, Ireland.Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M10-2116. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoShould Patients With Stroke Wear Compression Stockings to Prevent Venous Thromboembolism? Clive Kearon and Martin O'Donnell Should Patients With Stroke Wear Compression Stockings? Nikola Sprigg , Chamila M. Geeganage , and Philip M.W. Bath Metrics 5 April 2011Volume 154, Issue 7 Page: 506-507 Keywords Anticoagulant therapy Aspirin Conflicts of interest Disclosure Hemorrhage Hemorrhagic stroke Heparin Ischemic stroke Stroke Tinzaparin ePublished: 5 April 2011 Issue Published: 5 April 2011 Copyright & PermissionsCopyright © 2011 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...