Absorption of Vancomycin
Authors: Michael N. Dudley, Richard Quintiliani, Charles H. Nightingale, Nancy Gontarz
Journal: Annals of Internal Medicine (1984)

Letters and Corrections1 July 1984Absorption of VancomycinMICHAEL N. DUDLEY, PHARM, D., RICHARD QUINTILIANI, M.D., CHARLES H. NIGHTINGALE, PH.D., NANCY GONTARZ, B.S.MICHAEL N. DUDLEY, PHARM, D., RICHARD QUINTILIANI, M.D., CHARLES H. NIGHTINGALE, PH.D., NANCY GONTARZ, B.S.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-101-1-144_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: A report describing systemic absorption of vancomycin after oral administration in a patient with renal failure and Clostridium difficile-induced pseudomembranous colitis appeared in the April issue (1). We recently assayed single serum samples collected from 12 patients with varying degrees of renal function who were receiving oral vancomycin, 500 mg four times daily, for toxin-proven, C. difficile-induced, antibiotic-associated diarrhea and colitis. Samples were collected early in the course (within the first 4 days of therapy), before attaining a clinical response, to assess the effect of active C. difficile-induced diarrhea or colitis on vancomycin absorption.Serum vancomycin concentrations...References1. SPITZERELIOPOULOS PG. Systemic absorption of enteral vancomycin in a patient with pseudomembranous colitis. Ann Intern Med. 1984;100:533-4. LinkGoogle Scholar2. GERACIHEILMANNICHOLSWELLMANROSS JFDWG. Some laboratory and clinical experiences with a new antibiotic, vancomycin. Proc Staff Meet Mayo Clin. 1956;31:564-82. MedlineGoogle Scholar3. FARBERMOELLERING BR. Retrospective study of the toxicity of preparations of vancomycin from 1974 to 1981. Antimicrob Agents Chemother. 1983;23:138-41. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Hartford Hospital Hartford, CT 06115 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByNew Insights Into the Pharmacokinetics of Vancomycin After Oral and Intravenous Administration: An Investigation in Beagle DogsDoes oral vancomycin use necessitate therapeutic drug monitoring?Sexually Dimorphic Influence of Neonatal Antibiotics on BoneAn ultra-sensitive UHPLC-MS/MS assay for the quantification of orally administered vancomycin in plasmaGlycopeptides, Lipopeptides, and LipoglycopeptidesPediatric Primary Sclerosing CholangitisPharmacokinetics of LFF571 and Vancomycin in Patients with Moderate Clostridium difficile InfectionsRisk Factors for Systemic Vancomycin Exposure Following Administration of Oral Vancomycin for the Treatment of Clostridium difficile InfectionSystemic absorption of oral vancomycin in patients with Clostridium difficile infectionGlycopeptides, Lipopeptides, and LipoglycopeptidesFaecal pharmacokinetics of orally administered vancomycin in patients with suspected Clostridium difficile infectionTreatment of Clostridium difficile infection in older adultsSystemic absorption of oral vancomycin in a peripheral blood stem cell transplant patient with severe graft-versus-host disease of the gastrointestinal tractMaculopapular Rash Induced by Oral VancomycinSignificant Absorption of Oral Vancomycin in a Patient with Clostridium difficile Colitis and Normal Renal FunctionPossible Red-Man Syndrome Associated with Systemic Absorption of Oral Vancomycin in a Child with Normal Renal FunctionClinical Pharmacokinetics of Anti-InfectivesGastrointestinal InfectionOral Vancomycin-Induced Rash: Case Report and Review of the LiteratureRed Man Syndrome after Oral VancomycinAaron D. Killian, BScPharm, Jan V. Sahai, PharmD, Ziad A. Memish, MDAntibiotics: VancomycinSystemic Absorption of Oral Vancomycin in Patients With Renal Insufficiency and Antibiotic-Associated ColitisVancomycin: An UpdateVancomycin and necrotising enterocolitis. 1 July 1984Volume 101, Issue 1Page: 144-144KeywordsAttentionC difficile colitisClostridiumColitisDiarrheaOral administrationRenal failureVancomycin Issue Published: 1 July 1984 PDF DownloadLoading ...