Bone Densitometry and Clinical Decision-Making in Osteoporosis
Authors: B. Lawrence Riggs
Journal: Annals of Internal Medicine (1988)

Editorials1 February 1988Bone Densitometry and Clinical Decision-Making in OsteoporosisB. Lawrence Riggs, M.D., Heinz W. Wahner, M.D.B. Lawrence Riggs, M.D.Search for more papers by this author, Heinz W. Wahner, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-108-2-293 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptDuring the last 6 years the development of methods that measure bone mineral density accurately at important sites of fracture represents a real advance in care of patients with osteoporosis, a disease costing $7 to $10 billion annually in the United States (1). The bone mineral density of the axial skeleton, formerly only crudely estimated from roentgenograms can now be measured with a precision of 2% to 3% by dual photon absorptiometry for the vertebrae or proximal femur (2) and of 3% to 5% by quantitative computed tomography for the vertebrae (3). Precision is defined as (standard deviation of replicate...References1. CULLITON B. Osteoporosis reexamined: complexity of bone biopsy is a challenge. Science. 1987;235:833-4. CrossrefMedlineGoogle Scholar2. MAZESS R. The noninvasive measurement of skeletal mass. In: PECK WA, ed. Bone and Mineral Research Annual I. Amsterdam: Excerpta Medica; 1983:223-79. Google Scholar3. ROSENTHALGANOTTWYSHAKSLOVIKDOPPELTNEER DMGDSR. Quantitative computed tomography for spinal density measurement: factors affecting precision. Invest Radiol. 1985;20:306-10. CrossrefMedlineGoogle Scholar4. . Bone mineral densitometry. Ann Intern Med. 1987;107:932. LinkGoogle Scholar5. MAZESS R. On aging bone loss. Clin Orthop. 1982;165:239-52. CrossrefGoogle Scholar6. RIGGSMELTON BL. Involutional osteoporosis. N Engl J Med. 1986;314:1676-86. CrossrefMedlineGoogle Scholar7. OTTKILCOYNECHESNUT SRC. Ability of four different techniques of measuring bone mass to diagnose vertebral fractures in postmenopausal women. J Bone Min Res. 1987;2:201-10. CrossrefMedlineGoogle Scholar8. LINDSAYHARTFORRESTBAIRD RDCC. Prevention of spinal osteoporosis in oophorectomised women. Lancet. 1980;2:1151-3. CrossrefMedlineGoogle Scholar9. ETTINGERGENANTCANN BHC. Long-term estrogen replacement therapy prevents bone loss and fractures. Ann Intern Med. 1985;102:319-24. LinkGoogle Scholar10. CONSENSUS CONFERENCE: OSTEOPOROSIS. JAMA. 1984;252:799-802. CrossrefMedlineGoogle Scholar11. HENDERSONROSSPAGANINI-HILLMACK BRAT. Estrogen use and cardiovascular disease. Am J Obstet Gynecol. 1986; 154:1181-6. CrossrefMedlineGoogle Scholar12. WILSONGARRISONCASTELLI PRW. Postmenopausal estrogen use, cigarette smoking, and cardiovascular morbidity in women over 50: the Framingham study. N Engl J Med. 1985;313:1038-43. CrossrefMedlineGoogle Scholar13. WAHNERDUNNBROWNHAUSERMORIN HWMMR. Comparison of quantitative digital radiography and dual photon absorptiometry for bone measurements of the lumbar spine. Proceedings of the Second International Workshop on Non-Invasive Bone Measurements. Leuven; Belgium, September, 1987. In press. Google Scholar14. HEANEY R. En recherche de la difference (P < .05). Bone Min. 1986;1:99-114. MedlineGoogle Scholar15. CUMMINGSBLACK SD. Should perimenopausal women be screened for osteoporosis? Ann Intern Med. 1986;104:817-23. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Mayo Clinic and Foundation Rochester, Minnesota PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySetting a standard for a “silent” disease: defining osteoporosis in the 1980s and 1990sThe importance of severity of arthrosis for the reliability of bone mineral density measurement in womenThe impact of clothing style on bone mineral density among women in TurkeyPhysician characteristics associated with the use of bone densitometryAttitudes and Beliefs of Family Physicians and Gynecologists in Relation to the Prevention and Treatment of OsteoporosisPrediction of Peripheral Fracture Risk by Quantitative MicrodensitometryOsteoporosis and Other Disorders of Skeletal AgingOsteoporosis from the Perspective of a RadiologistAtrophy of the proximal part of the femur after total hip arthroplasty without cement. 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Conrad Johnston Jr., MDA Clinical Approach to Body Composition in WastingDisorders of Skeletal AgingBone Mass Throughout Life: Bone Growth and InvolutionClinical indications for bone mass measurementsOsteoporosis and the ElderlyMonitoring skeletal response to estrogenMethodological issues in comparing genetic and environmental influences on bone massModern Therapeutic Approaches to OsteoporosisDefining osteoporosisIssues of Aging in Preventive Medicine and the Example of OsteoporosisOsteoporosis in a 58-Year-Old WomanBone Mineral DensitometryComparison of Dual-Energy X-Ray Absorptiometry and Dual Photon Absorptiometry for Bone Mineral Measurements of the Lumbar SpineDiagnostic Evaluation of OsteoporosisSkeletal Fragility in the Elderly 1 February 1988Volume 108, Issue 2Page: 293-295KeywordsBone densityBone developmentComputed axial tomographyDensitometryFemurOsteoporosisPhoton absorptiometrySkeletonStandard deviationVertebrae Issue Published: 1 February 1988 PDF downloadLoading ...