Food and Drug Administration Approval of BuprenorphineNaloxone for Office Treatment of Addiction
Authors: Richard B. Resnick
Journal: Annals of Internal Medicine (2003)

Letters18 February 2003Food and Drug Administration Approval of BuprenorphineNaloxone for Office Treatment of AddictionRichard B. Resnick, MDRichard B. Resnick, MDNew York University School of Medicine; New York, NY 10025-7113 (Resnick)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-138-4-200302180-00027 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Many persons addicted to opium decline available treatment methods but accept buprenorphine, particularly when it is offered in a private office (1). On 8 October 2002, the U.S. Food and Drug Administration approved buprenorphine, a schedule III partial morphine agonist, for treatment of opioid dependence. This approval, together with provisions in the Drug Addiction Treatment Act of 2000, expands the venues for the treatment of opioid dependence from specially licensed methadone facilities to physicians' private offices, where schedule III to schedule V drugs can be prescribed. Expansion of treatment to private practice creates opportunities to provide holistic ...References1. Resnick RB, Galanter M, Resnick E, Pycha C. Buprenorphine treatment of heroin dependence (detoxification and maintenance) in a private practice setting. J Addict Dis. 2001;20:75-83. [PMID: 11318399] CrossrefMedlineGoogle Scholar2. Raisch DW, Fye CL, Boardman KD, Sather MR. Opioid dependence treatment, including buprenorphine/naloxone. Ann Pharmacother. 2002;36:312-21. [PMID: 11847954] CrossrefMedlineGoogle Scholar3. Fudala PJ, Yu E, Macfadden W, Boardman C, Chiang CN. Effects of buprenorphine and naloxone in morphine-stabilized opioid addicts. Drug Alcohol Depend. 1998;50:1-8. [PMID: 9589267] CrossrefMedlineGoogle Scholar4. Resnick RB, Galanter M, Pycha C, Cohen A, Grandison P, Flood N. Buprenorphine: an alternative to methadone for heroin dependence treatment. Psychopharmacol Bull. 1992;28:109-13. [PMID: 1609035] MedlineGoogle Scholar5. Amass L, Kamien JB, Mikulich SK. Efficacy of daily and alternate-day dosing regimens with the combination buprenorphine-naloxone tablet. Drug Alcohol Depend. 2000;58:143-52. [PMID: 10669065] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: New York University School of Medicine; New York, NY 10025-7113 (Resnick)Acknowledgments: The author thanks Charles O'Keeffe and Elaine Resnick, MSW, for editorial suggestions.Grant Support: In part by a research grant from the National Institute of Drug Abuse (RO1DA10728). PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAnalgetikaAnalgetikaMetabolic and toxicological considerations of the opioid replacement therapy and analgesic drugs: methadone and buprenorphineBuprenorphineOpioid Addiction and Abuse in Primary Care Practice: A Comparison of Methadone and Buprenorphine as Treatment OptionsCurrent options in the management of opioid dependence: A reviewManaging Pain in the Addicted PatientPharmacokinetics of Buprenorphine: A Comparison of Sublingual Tablet Versus Liquid after Chronic DosingNeeds and scientific opportunities for research on substance abuse treatment among Hispanic adultsPharmacokinetics, bioavailability and opioid effects of liquid versus tablet buprenorphineEffects of monoamine oxidase inhibitors on cocaine discrimination in ratsBuprenorphine for pain management physicians: A dilemma or a therapeutic alternative?Pharmacists’ and Technicians’ Perceptions and Attitudes Toward Dispensing Buprenorphine/Naloxone to Patients with Opioid DependenceBuprenorphine 18 February 2003Volume 138, Issue 4Page: 360KeywordsDrug addictionDrugsFood and Drug AdministrationOpioid addictionOpioidsPrevention, policy, and public healthPsychosocial therapyResearch grantsSafetySubstance abuse ePublished: 18 February 2003 Issue Published: 18 February 2003 Copyright & PermissionsCopyright © 2003 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...