Hypertrophic Osteoarthropathy in Portal Cirrhosis
Authors: D. J. BUCHAN
Journal: Annals of Internal Medicine (1967)

Case Studies1 January 1967Hypertrophic Osteoarthropathy in Portal CirrhosisD. J. BUCHAN, M.D., F.A.C.P., F.R.C.P.(C), D. M. MITCHELL, M.D.D. J. BUCHAN, M.D., F.A.C.P., F.R.C.P.(C)Search for more papers by this author, D. M. MITCHELL, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-66-1-130 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptA recent paper by Vogl and Goldfischer (1) outlines the development of our ideas of hypertrophic osteoarthropathy. The occurrence of cyanosis and clubbing in a variety of diseases including those of the lung, heart, and liver has been recognized for centuries. However, the complete syndrome of pachydermoperiostosis has not been as clearly related to diseases in these various organs. The complete syndrome includes clubbing of the fingers and toes, cylindrical enlargement of legs and arms due to involvement of periosteal bone as well as of the skin, synovitis with joint effusion, and progressive coarsening of the face due to thickening...References1. VOGLGOLDFISCHER AS: Pachydermoperiostosis. Primary or idiopathic hypertrophic osteoarthropathy. Amer. J. Med. 33: 166, 1962. CrossrefMedlineGoogle Scholar2. HAMMARSTENO'LEARY JFJ: The features and significance of hypertrophic osteoarthropathy. Arch. Intern. Med. (Chicago) 99: 431, 1957. CrossrefGoogle Scholar3. MENDLOWITZ M: Clubbing and hypertrophic osteoarthropathy. Medicine (Balt.) 21: 269, 1942. CrossrefGoogle Scholar4. TZONEVA-MANEVABOSAJIEVAPETROV MTEB: Chromosomal abnormalities in idiopathic osteoarthropathy. Lancet 1: 1000, 1966. CrossrefMedlineGoogle Scholar5. RODMANSOBELCLOSE TMHP: Arterial oxygen unsaturation and the ventilation-perfusion defect of Laennec's cirrhosis. New Eng. J. Med. 263: 73, 1960. CrossrefMedlineGoogle Scholar6. MURRAYDAWSONSHERLOCK JFAMS: Circulatory changes in chronic liver disease. Amer. J. Med. 24: 358, 1958. CrossrefMedlineGoogle Scholar7. BERTHELOTWALKERSHERLOCKREID PJGSL: Arterial changes in the lungs in cirrhosis of the liver—lung spider nevi. New Eng. J. Med. 274: 291, 1966. CrossrefMedlineGoogle Scholar8. RATNOFFPATEK ODAJ: Natural history of Laennec's cirrhosis of liver; analysis of 386 cases. Medicine (Balt.) 21: 207, 1942. CrossrefGoogle Scholar9. MEANSBROWN MGNW: Secondary hypertrophic osteoarthropathy in congenital heart disease. Amer. Heart J. 34: 262, 1947. CrossrefMedlineGoogle Scholar10. GINSBURGBROWN JJB: Increased oestrogen excretion in hypertrophic pulmonary osteoarthropathy. Lancet 2: 1274, 1961. CrossrefMedlineGoogle Scholar11. HOLLINGBRODEYBOLAND HERSHC: Pulmonary hypertrophic osteoarthropathy. Lancet 2: 1269, 1961. CrossrefMedlineGoogle Scholar12. YOUNG JR: Ulcerative colitis and finger clubbing. Brit. Med. J. 1: 278, 1966. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Saskatoon, Saskatchewan,From the Department of Medicine, University Hospital and the University of Saskatchewan, Saskatoon, Saskatchewan, Canada.This paper was presented at the Manitoba-Saskatchewan regional meeting of the American College of Physicians, Winnipeg, Manitoba, Canada, on February 10, 1966.Requests for reprints should be addressed to D. J. Buchan, M.D., Department of Medicine, University Hospital, University of Saskatchewan, Saskatoon, Saskatchewan, Canada. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe Nail in Systemic DiseasePaquidermoperiostosis (síndrome de Touraine-Solente-Golé). Descripción de un casoPachydermoperiostosis (Touraine-Solente-Golé syndrome). Case reportCONGENITAL MEGAESOPHAGUS WITH HYPERTROPHIC OSTEOPATHY IN A 6-YEAR-OLD DOGHepatic hypertrophic osteoarthropathy and liver transplantation.Rheumatic complications of alcohol abuseCytokines. A unifying concept in the pathogenesis of clubbingHypertrophic pulmonary osteoarthropathy in association with a bronchial carcinoid tumourParaneoplastische OsteopathieParaneoplastische OsteopathieHypertrophic osteoarthropathy: A 10-year retrospective analysisHypertrophic osteoarthropathy of the lower extremities as a manifestation of arterial graft sepsisHypertrophic hepatic osteoarthropathyHypertrophic osteoarthropathy and rheumatoid arthritis. Simultaneous occurrence in association with diffuse interstitial fibrosisHypertrophic pulmonary osteoarthropathy and its occurrence with pulmonary metastases from renal carcinoma.Die Nativdiagnostik der Lebererkrankungen im RöntgenbildHypertrophic osteoarthropathy secondary to sub-phrenic abscessPeriosteal new bone formation in polyarteritis nodosa. A syndrome involving the lower extremitiesA common factor in hypertrophic osteoarthropathyHypertrophic osteoarthropathy in a gibbon ( Hylobates lar )A New Syndrome Associated With Hepatocellular CarcinomaNineteenth rheumatism review. Part-IIIHYPERTROPHIC OSTEOARTHROPATHY: REPORT OF A RARE ASSOCIATION WITH ENDOCARDITISHypertrophic osteoarthropathy associated with carcinoma of the oesophagus.Hypertrophic Osteoarthropathy and PregnancyERNEST C. BORDEN, M.D., H. EDWARD HOLLING, M.D., F.R.C.P., F.A.C.P.Hypertrophic osteoarthropathy with arthritis and synovial calcification in a patient with alcoholic cirrhosisPulmonary Hypertrophic Osteoarthropathy, Spider Angiomata, and Estrogen Hyperexcretion in NeoplasiaJOHN Y. JAO, M.D., JOSEPH J. BARLOW, M.D., MELVIN J. KRANT, M.D.Idiopathic hypertrophic osteoarthropathyNORMAL SEX-CHROMOSOME COMPLEMENT IN A CASE OF FAMILIAL OSTEOARTHROPATHY 1 January 1967Volume 66, Issue 1Page: 130-135KeywordsBoneCirrhosisDiagnostic radiologyHeart diseasesHospital medicineLiverLiver diseasesLungsResearch laboratories Issue Published: 1 January 1967 PDF downloadLoading ...