tbuckley/cabot-search huggingface dataset:
Organise an international medical meeting III: Registration and its problems.
Authors: I Capperauld, A I Macpherson
Journal: BMJ (1978)

achievement in having promoted the return to learning of the medical profession.The leaders of organised medicine may congratulate themselves at having fended off consumerist and demagogic outcries for recertification and other government controls; and the drug companies would rather pay for education than for calendars and doctor's bags.There is, in addition, in these days of economic stagnation, the prospect of creating many new jobs for professionals, administrators, and clerks-who will do nothing in particular but do it very well.And un- doubtedly before long other professions such as lawyers, pharmacists, plumbers, watchmakers, and legislators should join in the learning stampede and develop their own continuing education programmes, complete with categories, hours, criteria, credits, and self-evaluation feedback mechanisms.
TO THE MEDICAL PROFESSION OF THE UNITED STATES
Authors: John A. Wyeth
Journal: JAMA (1902)

The necessity for a thorough organization of the medical profession was never more urgent than at the present moment, nor has the appreciation of this necessity ever been more keenly felt than at this time. The American Medical Association, which will hold its fifty-third annual session at Saratoga on June 10, 1902, being the only national representative association of the medical profession in the United States, is entitled to and claims the earnest support of every medical practitioner who has at heart the highest and best interests of the profession. An organized profession represented in this great central bodv with affiliated and influential state and territorial associations extending through their subdivisions into all the districts or counties, is the only real guarantee of the protection of the public health and of the medical profession. The enactment and enforcement of rigid medical laws; the establishment of reciprocity or interstate comity by
Heroin Overdose Complicated by Intravenous Injection of Milk
Authors: Ernst J. Drenick
Journal: JAMA (1970)

To the Editor.—  A new complication can be added to the lengthening list of disease states associated with narcotics addiction. A rumor among heroin addicts is that milk is endowed with the ability to counteract the ill effects of heroin overdosage. In such circumstances, quantities of milk are injected intravenously with potentially catastrophic results as can be gleaned from the following brief report.  Report of a Case.—  According to statements by a relative, a 19-year-old Marine had consumed one-half pint of rum, four to eight barbiturate tablets, and injected one balloon of heroin. He quickly became lethargic. Alarmed over the deepening stupor, some of the patient's friends then decided to inject two syringes of milk into the antecubital vein as an antidote. The patient's condition immediately worsened. The good samaritans had vanished by the time an ambulance arrived, and no precise information was obtainable regarding the quantity or the type
Free speech is at risk from UK libel law, says Danish radiologist
Authors: Z. Kmietowicz
Journal: BMJ (2009)

A leading Danish radiologist has said that the lives of patients in England are being put at risk because libel laws are preventing doctors and scientists from speaking in public about their clinical experiences.

Henrik Thomsen, professor of radiology at the University of Copenhagen, is being pursued in the High Court in London by GE Healthcare over allegations that he defamed the company at a conference in Oxford in 2007.

Professor Thomsen is reported to have described gadodiamide (Omniscan), an injectable contrast agent made by GE Healthcare that is used in magnetic resonance imaging, as a medical “nightmare.” He told colleagues at the conference that the drug caused nephrogenic systemic fibrosis in about 30 patients with kidney problems in Copenhagen University Hospital, where he worked. 

Professor Thomsen’s lawyer, Andrew Stephenson, from the firm Carter-Ruck, said that GE Healthcare claims that Professor Thomsen accused the company of suppressing information about Omniscan, among other things. His comments were reported in an article …
Diagnosis and characterization of acute erythroleukemia subsets by determining the percentages of myeloblasts and proerythroblasts in 69 cases
Authors: Areta Kowal-Vern, Fermina M. Mazzella, James D. Cotelingam, M. Atef Shrit, James T. Rector, Harold R. Schumacher
Journal: American Journal of Hematology (2000)

Acute erythroleukemia (FAB M6) is a rare heterogeneous disease with an increase in red cell precursors and myeloblasts. Three subsets have been described: M6A (myeloblast-rich erythroleukemia); M6B (proerythroblast-rich erythroleukemia); and M6C (myeloblast- and proerythroblast-rich mixed variant). This study was undertaken to define and compare the clinical courses and survival outcomes among M6A, M6B, and M6C variants of erythroleukemia. Sixty-nine cases of M6 leukemia were categorized as consisting of >/=50% erythroid of all nucleated cells and M6A with >/=30% myeloblasts/nonerythroid component; M6B with >/=30% proerythroblasts/erythroid component; and M6C with >/=30% myeloblasts and >/=30% proerythroblasts. The demographics, cell type distribution, and survival (mean +/- sd) of these groups were compared. There were 32 M6A, 26 M6B, and 11 M6C patients. No significant difference was seen among the groups in age, sex, or treatment. Compared to M6A, both the M6B (P< 0.0001) and M6C (P< 0.0001) variants showed a statistically significant increase in the percentage of bone marrow erythroid cells, proerythroblasts, and the proerythroblasts/erythroid ratios. Comparing the groups for survival, M6B (3 +/- 3.6 months) versus M6A (25 +/- 28 months), P< 0. 002, and M6C (10 +/- 13 months) versus M6A, P< 0.01 had a poorer prognosis. Calculating the proerythroblasts as a component of total bone marrow erythroids provides a complimentary method for delineating the pure red cell erythroleukemia (M6B) and mixed variant (M6C), similar to that for the myeloid/erythroid (M6A) leukemia. Now that it is possible to delineate erythroleukemia subtypes, innovative treatments are indicated to target the malignant erythroid population, which is resistant to myeloid-based therapies.
Association between bullous pemphigoid and psoriasis
Authors: R. Baran, P. Brun
Journal: British Journal of Dermatology (1986)

Journal Article Association between bullous pemphigoid and psoriasis Get access R. Baran, R. Baran 42 Rue des Serbes, 06400 Cannes, France Search for other works by this author on: Oxford Academic Google Scholar P. Brun P. Brun 42 Rue des Serbes, 06400 Cannes, France Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 114, Issue 4, 1 April 1986, Page 516, https://doi.org/10.1111/j.1365-2133.1986.tb02863.x Published: 01 April 1986
Methotrexate-Induced Liver Toxicity
Authors: Bruce E. Strober
Journal: JAMA Dermatology (2014)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Dermatology HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Dermatology journal
Food Exposure in Patients with Bulimia nervosa
Authors: Peter Neudeck, Irmela Florin, Brunna Tuschen-Caffier
Journal: Psychotherapy and Psychosomatics (2001)

&lt;i&gt;Background:&lt;/i&gt; The aim of the study was to investigate psychological and physiological responses of bulimic patients to the repeated presentation of food cues. &lt;i&gt;Method:&lt;/i&gt; On 2 subsequent days, 48 bulimic women (DSM-IV) were confronted with high- or low-caloric food for 20 min. A control group (n = 24) was exposed to high-caloric food once. Blood sugar levels were manipulated with a glucose load. &lt;i&gt;Results:&lt;/i&gt; High-caloric food only elicited increases in urge to binge, subjective and physiological stress in the first session. During the second session, reported urge to binge and subjective stress was significantly lower. Bulimic patients confronted with high-caloric food showed higher subjective and physiological stress in the first session compared to bulimic patients confronted with low-caloric food. In the second session, they reported more subjective stress and urge to binge, compared to the low-caloric group. Blood sugar levels did not affect psychological and physiological responses. &lt;i&gt;Discussion:&lt;/i&gt; The results are discussed in terms of the conditioning model of binge eating model, habituation models and implications for exposure therapy.
Protective activity of antibodies to exotoxin A and lipopolysaccharide at the onset of Pseudomonas aeruginosa septicemia in man.
Authors: M Pollack, L S Young
Journal: Journal of Clinical Investigation (1979)

Serum antibodies to exotoxin A and type-specific lipopolysaccharide were measured by passive hemagglutination in 52 patients with Pseudomonas aeruginosa septicemia. Their comparative protective activities were evaluated by relating the titers of each at the onset of bacteremia to subsequent outcome. High acute serum antitoxin and antilipopolysaccharide titers (log2 reciprocal mean titers greater than 5) were associated with survival (76% of 17 with high vs. 46% of 24 with low antitoxin titers, P = 0.05; 85% of 13 with high vs. 48% of 29 with low antilipopolysaccharide titers, P = 0.03). In contrast, neither antibody titer was significantly associated (P less than or equal to 0.05) with patients' age or sex, severity of underlying disease, presence of leukopenia, steroid or immunosuppressive therapy. Despite a correlation between acute titers of the two antibodies (r = 0.33, P = 0.06), they appeared to protect independently and additively. Whereas 75% of 8 patients with high antitoxin titers and only 38% of 16 with low titers survived with low antilipopolysaccharide titers (P = 0.10), 100% (6/6), 73% (8/11), and 38% (6/16) survived, respectively, when both, one, or neither antibody was present in high titer (P = 0.01). Furthermore, the association between high acute serum antitoxin titers and survival was more pronounced in patients with rapidly fatal underlying disease (P = 0.06) and leukopenia (P = 0.12) than in more favorable prognostic and immune categories. These data indicate that serum antibodies to exotoxin A and lipopolysaccharide are found in most patients with P. aeruginosa septicemia and both are protective. Both antibodies may have therapeutic or prophylactic potential, whereas serum antiexotoxin A antibodies may be particularly beneficial in compromised hosts.
The Practice of International Health: A Case-Based Orientation
Authors: Frank J. Bia
Journal: Annals of Internal Medicine (2009)

Medical Writings: Book Notes20 October 2009The Practice of International Health: A Case-Based OrientationFrank J. Bia, MD, MPHFrank J. Bia, MD, MPHFrom Yale School of Medicine, New Haven, and AmeriCares Foundation, Stamford, Connecticut.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-151-8-200910200-00028 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Perlman D, Roy A, eds. 288 pages. New York: Oxford Univ Pr; 2009. $59.50. ISBN 9780195310276. Order at www.oup.com/us.Field of medicine: Global medicine, disaster relief, public health, medical anthropology, social medicine, women's studies, and gender politics.Audience: Clinicians; public and global health practitioners; medical, nursing, and public health students; humanitarian relief workers, medical missionaries, and anthropologists; Peace Corps volunteers; and gender and health equity advocates.Purpose: To provide insights into global health practices through personal, place-based narratives describing formative experiences for individuals who have contributed uniquely to global health.Content: A superb forward by Dr. Paul Farmer is complemented ... Author, Article, and Disclosure InformationAffiliations: From Yale School of Medicine, New Haven, and AmeriCares Foundation, Stamford, Connecticut. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 20 October 2009Volume 151, Issue 8Page: 592KeywordsAllied health care professionalsBirthCrimeFallsGlobal healthObstetrics and gynecologyPrevention, policy, and public healthSexual identity ePublished: 20 October 2009 Issue Published: 20 October 2009 Copyright & PermissionsCopyright © 2009 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
The real-life/laboratory controversy as viewed from the cognitive neurobiology of animal learning and memory
Authors: Howard Eichenbaum
Journal: Behavioral and Brain Sciences (1996)

Abstract Parallel to Koriat &amp; Goldsmith's accounting of human memory, there are two distinct approaches in animal learning. Behaviorist approaches focus on quantitative aspects of conditioned response probability, whereas cognitive and ethological approaches focus on qualitative aspects of how memory is used in real life. Moreover, in animal research these distinguishable measures of memory are dissociated in experimental amnesia.
Race, Site of Care, and Hospital Readmission Rates—Reply
Authors: Karen E. Joynt, E. John Orav, Ashish K. Jha
Journal: JAMA (2011)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Insulin Production Rate in Normal Man as an Estimate for Calibration of Continuous Intravenous Insulin Infusion in Insulin-dependent Diabetic Patients
Authors: W K Waldhäusl, P R Bratusch-Marrain, M Francesconi, P Nowotny, A Kiss
Journal: Diabetes Care (1982)

This study examines the feasibility of deriving the 24-h insulin requirement of insulin-dependent diabetic patients who were devoid of any endogenous insulin release (IDD) from the insulin-production rate (IPR) of healthy man (basal, 17 mU/min; stimulated 1.35 U/12.5 g glucose). To this end, continuous intravenous insulin infusion (CIVII) was initiated at a precalculated rate of 41.2 ± 4.6 (SD) U/24 h in IDD (N = 12). Blood glucose profiles were compared with those obtained during intermittent subcutaneous (s.c.) insulin therapy (IIT) and those of healthy controls (N = 7). Regular insulin (Hoechst CS) was infused with an adapted Mill Hill Infuser at a basal infusion rate of 1.6 U/h (6:00 a.m. to 8:00 p.m.), and of 0.8 U/h from 8:00 p.m. to 6:00 a.m. Preprandial insulin (3.2–6.4 U) was added for breakfast, lunch, and dinner. Daily individual food intake totaled 7688 ± 784 kJ (1836 ± 187 kcal)/24 h including 184 ± 37 g of glucose. Proper control of blood glucose (BG) (mean BG 105 ± 10 mg/dl; mean amplitude of glycemic excursions 54 ± 18 mg/dl; and 1 h postprandial BG levels not exceeding 160 mg/dl) and of plasma concentrations of β-hydroxybutyrate and lactate was maintained by 41.4 ± 4.4 U insulin/24 h. Although BG values only approximated the upper normal range as seen in healthy controls, they were well within the range reported by others during CIVII. Therefore, we conclude that in adult IDD completely devoid of endogenous insulin (1) the IPR of normal man can be used during CIVII as an estimate for the patient's minimal insulin requirement per 24 h, and (2) this approach allows for a blood glucose profile close to the upper range of a normal control group. Thus, deriving a patient's daily insulin dose from the insulin production rate of healthy man may add an additional experimental protocol which aids in making general calculations of a necessary insulin dose instead of using trial and error or a closed-loop insulin infusion system.
Emergency and early management of burns and scalds
Authors: S. Enoch, A. Roshan, M. Shah
Journal: BMJ (2009)

#### Summary points 

Burn injuries are an important global health problem. Most simple burns can be managed by general practitioners in primary care, but complex burns and all major burns warrant a specialist and skilled multidisciplinary approach for a successful clinical outcome. This article discusses the principles behind managing major burns and scalds using an evidence based approach and provides a framework for managing simple burns in the community.

#### Sources and selection criteria

We searched Medline, Ovid, Burns, and the Cochrane Library until June 2008 for randomised controlled trials, systematic reviews, evidence reports, and recent evidence based guidelines from international burn associations.

Annually in the United Kingdom, around 175 000 people attend accident and emergency departments with burns from various causes (box 1).1 This represents 1% of all emergency department attendances, and about 10% of these patients need inpatient management in a specialist unit.2 A further 250 000 patients are managed in the community by general practitioners and allied professionals. Of patients referred to hospital, some 16 000 are admitted, and about 1000 patients need active fluid resuscitation. The number of burns related deaths average 300 a year.1

#### Box 1 Some important causes of burns and scalds

Globally, the World Health Organization estimates that 322 000 people die each year from …
Silencing of ETV6/RUNX1 abrogates PI3K/AKT/mTOR signaling and impairs reconstitution of leukemia in xenografts
Authors: G Fuka, H-P Kantner, R Grausenburger, A Inthal, E Bauer, G Krapf, U Kaindl, M Kauer, M N Dworzak, D Stoiber, O A Haas, R Panzer-Grümayer
Journal: Leukemia (2011)
PATTERNS OF BIOCHEMICAL ORGANIZATION RELATED TO MORPHOLOGY
Authors: NATHAN S. KLINE, NANCY WERTHEIMER, CORA G. DYER, ANNA SCHENKER, BETTY RUBIN, RONALD SNIFFEN
Journal: American Journal of Psychiatry (1953)

1.Significant linear correlations between somatotype and certain biochemical indices have been demonstrated. 2. In addition to linear relationships the existence of more discriminant patterns involving both sex of the subjects and morphological groupings is illustrated. 3. By cross correlations of the various indices, individuals are shown to have a typical pattern relative to the rest of the group, which may be even more consistent than the pattern based on morphology.
The Endocrinologist Gets a Hair Transplant
Authors: D. A. Feinfeld
Journal: Annals of Internal Medicine (2004)

Ad Libitum19 October 2004The Endocrinologist Gets a Hair TransplantD. A. Feinfeld, MDD. A. Feinfeld, MDFrom Eastchester, NY 10709.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-141-8-200410190-00014 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail At least he, of all men, knowshow it happened: the male humors,overflowing his dangling vanity,spread through thickened blood.His uneasy nights itchedwith pulsing in groin and chin,bidding hairs grow, but as the stormstrips poplars bare, the earth tuggedat his topknot where famished rootsfailed at last.As the crown bared, its cover flungby the breeze in the whirling calendar,he bid his surgeon resodthat skull-top with fertile clumpsscooped from blooming chest and neck.A modern Sisyphus, he knows the stoneshoved to the sharp, barren crestwill again, despite potion and spell,fall in a virile wind to jointhe waiting dust. Author, Article, and Disclosure InformationAffiliations: From Eastchester, NY 10709.Current Author Address: D.A. Feinfeld, MD, 32 Waterside Close, Eastchester, NY 10709. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 19 October 2004Volume 141, Issue 8Page: 643KeywordsBloodDustFallsStormsSurgeonsThorax ePublished: 19 October 2004 Issue Published: 19 October 2004 Copyright & PermissionsCopyright © 2004 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Kupffer cell prostaglandin-E2 production is amplified during hepatic regeneration
Authors: Mark P. Callery, Martin J. Mangino, Wayne M. Flye
Journal: Hepatology (1991)

Prostaglandin-E2 increases in liver tissue after partial hepatectomy and stimulates DNA synthesis in primary cultures of hepatocytes. This study evaluated the capacity of Kupffer cells isolated at various intervals after partial hepatectomy to produce prostaglandin E2 in response to bacterial endotoxin. This stimulator of Kupffer cells is a normal endogenous component of portal venous blood. After partial hepatectomy (6 to 48 hr), when hepatic regeneration rates were greatest, regenerating liver Kupffer cells demonstrated a significantly greater capacity to produce prostaglandin E2 in response to bacterial endotoxin than did equal numbers of Kupffer cells from time-matched, sham-operated control animals. However, by 12 days after partial hepatectomy, when liver mass had been more than 83% restored, regenerating liver Kupffer cell prostaglandin E2 production had decreased to levels produced by sham KC. We postulate that high levels of Kupffer cell-derived prostaglandin E2 provide a critical paracrine signal fundamental to the initiation and control of growth by neighboring hepatocytes during liver regeneration.