tbuckley/cabot-search huggingface dataset:
Rapid-Response Systems as a Patient Safety Strategy
Authors: Bradford D. Winters, Sallie J. Weaver, Elizabeth R. Pfoh, Ting Yang, Julius Cuong Pham, Sydney M. Dy
Journal: Annals of Internal Medicine (2013)

Rapid-response systems (RRSs) are a popular intervention in U.S. hospitals and are supported by accreditors and quality improvement organizations. The purpose of this review is to evaluate the effectiveness and implementation of these systems in acute care settings. A literature search was performed between 1 January 2000 through 30 October 2012 using PubMed, PsycINFO, CINAHL, and the Cochrane Central Register of Controlled Trials. Studies published in any language evaluating outcome changes that occurred after implementing an RRS and differences between groups using and not using an RRS (effectiveness) or describing methods used by RRSs (implementation) were reviewed. A single reviewer (checked by a second reviewer) abstracted data and rated study quality and strength of evidence. Moderate-strength evidence from a high-quality meta-analysis of 18 studies and 26 lower-quality before-and-after studies published after that meta-analysis showed that RRSs are associated with reduced rates of cardiorespiratory arrest outside of the intensive care unit and reduced mortality. Eighteen studies examining facilitators of and barriers to implementation suggested that the rate of use of RRSs could be improved.
A US model for primary care in the NHS
Authors: Linda Hill
Journal: BMJ (2005)

★★★★ Ever wondered what it's like to be detained in Guantanamo Bay? Seven British volunteers, including several Muslims, were given the chance to find out, courtesy of Channel 4, as part of a week-long series of programmes on torture.Reporting to a specially equipped warehouse, they were ambushed, hooded, kidnapped, shackled, caged, and subjected to a range of Pentagon approved interrogation techniques that included sensory deprivation, "sleep adjustment," religious and sexual humiliation, and severe physical pain.But Torture: The Guantanamo Guidebook was no Big Brother-style reality show.This was a serious attempt to examine the effects of torture on the body and the psyche, and to bring home to viewers the kind of interrogation techniques that are being employed in the US-led so called "war on terror.""Tonight we recreate 48 hours in Guantanamo Bay," announced presenter Jon Snow, better known as the face of Channel 4 News."All the interrogation methods you see have been officially sanctioned by the US government and used to fight the war on terror."Using military manuals and declassified US government documents, Channel 4 had installed cages, interrogation rooms, and surveillance equipment to simulate Guantanamo's conditions and methods.But the volunteers, who had their own clothes torn and cut off and replaced with the trade-
Education of the Public Concerning Cancer
Authors: M. Donaldson
Journal: BMJ (1950)

CARDIAC NEUROSESBRnsH 35similar difficulties are bound to be encountered again.Therefore, little is gained by psychotherapy, the patient's character being virtually unchangeable.Nevertheless, it should be possible to prevent physical incapacity even in this type.Although a good physician should be able to deal with most cases of " cardiac neurosis," he should not hesitate to enlist the help of a psychiatrist if he can make no headway.
Problems with contraception play big part in unplanned pregnancies, study says
Authors: Janice Hopkins Tanne
Journal: BMJ (2008)

<h3>Abstract</h3> <h3>INTRODUCTION</h3> Longitudinal data is key to identifying cognitive decline and treatment response in Alzheimer’s disease (AD). <h3>METHODS</h3> The Automatic Story Recall Task (ASRT) is a novel, fully automated test that can be self-administered remotely. In this longitudinal case-control observational study, 151 participants (mean age: 69.99 (range 54-82), 73 mild cognitive impairment/mild AD and 78 cognitively unimpaired) completed parallel ASRT assessments on their smart devices over 7-8 days. Responses were automatically transcribed and scored using text similarity metrics. <h3>RESULTS</h3> Participants reported good task usability. Adherence to optional daily assessment was moderate. Parallel forms correlation coefficients between ASRTs were moderate-high. ASRTs correlated moderately with established tests of episodic memory and global cognitive function. Poorer performance was observed in participants with MCI/Mild AD. <h3>DISCUSSION</h3> Unsupervised ASRT assessment is feasible in older and cognitively impaired people. This automated task shows good parallel forms reliability and convergent validity with established cognitive tests.
THE USE OF BARE-METALS STENTS IN PRIMARY PERCUTANEOUS CORONARY INTERVENTION FOR ACUTE MYOCARDIAL INFARCTION: IS THERE A DIFFERENCE IN CLINICAL OUTCOME BETWEEN COBALT CHROMIUM VERSUS STAINLESS STEEL STENTS?
Authors: Angela Koh, Lok Man Choi, Lay Wai Khin, Ling Ling Sim, Terrance SJ Chua, Tian Hai Koh, Jack WC Tan, Stanley Chia
Journal: Journal of the American College of Cardiology (2010)
Isolation of the Human Immunodeficiency Virus from Cervical Secretions During Menses
Authors: MARTIN J. BLASER
Journal: Annals of Internal Medicine (1987)

Letters and Corrections1 June 1987Isolation of the Human Immunodeficiency Virus from Cervical Secretions During MensesMARTIN J. BLASER, M.D.MARTIN J. BLASER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-106-6-912_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: The report by Vogt and associates (1) indicates that the human immunodeficiency virus (HIV) may be isolated from cervical secretions of infected women at any point during the menstrual cycle, and that cervical secretions may yield HIV while simultaneous blood cultures are negative. However, the likelihood of a positive cervical culture does not appear constant throughout the menstrual cycle. My review of Figure 1 shows that 4 of 7 cervical cultures obtained during menses were positive compared with only 3 of 17 obtained outside menses (p= 0.077, Fisher's exact test). All three women who were healthy...References1. VOGTWITTCRAVEN MDD. Isolation patterns of the human immunodeficiency virus from cervical secretions during the menstrual cycle of women at risk for the acquired immunodeficiency syndrome. Ann Intern Med. 1987;106:380-2. LinkGoogle Scholar2. WOFSYCOHENHAUER CJL. Isolation of AIDS-associated retrovirus from genital secretions of women with antibody to the virus. Lancet. 1986;1:527-9. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: MARTIN J. BLASER, M.D.Affiliations: Veterans Administration Medical Center Denver, CO 80220 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byEffect of menstrual cycle on HIV-1 levels in the peripheral blood and genital tractPREGNANCY AND WOMEN AT RISK FOR HIV INFECTION 1 June 1987Volume 106, Issue 6Page: 912-912KeywordsBloodHIVMenstrual cycle ePublished: 1 December 2008 Issue Published: 1 June 1987 PDF downloadLoading ...
Demonstration of Renal Varices Using Technetium-99m Red Blood Cells in the Investigation of Recurrent Macroscopic Hematuria
Authors: IAN RENDAK, CESAR PISON, GUY DROUIN
Journal: Clinical Nuclear Medicine (1987)

A case of severe, recurrent, macroscopic hematuria in which the diagnosis of renal vein varices was suggested by Tc-99m red blood cell blood pool imaging is described. Current diagnostic modalities are discussed and an integrated use of this test is proposed.
THE THERAPEUTICS OF THE INTRAVENOUS DRIP
Authors: HAROLD THOMAS HYMAN
Journal: JAMA (1933)

"The rapid intravenous introduction of pharmacologically active or inert chemicals, drugs and biologic fluids may frequently give rise to immediate and far-reaching nonspecific sequelae, at times serious and occasionally fatal."<sup>1</sup>This syndrome ("speed shock") includes circulatory and respiratory symptoms, together with alterations in the blood. The reaction is immediate and may include or closely simulate such apparently unrelated phenomena as the anaphylactoid reaction,<sup>2</sup>nitritoid and hemoclastic crises, post-transfusion reactions,<sup>3</sup>peptone shock, and the sudden death that has been described following intravenous injections.<sup>4</sup> These untoward reactions may be avoided by the slow continuous "intravenous drip."<sup>5</sup>The clinical application of this principle is by no means new and has been emphasized by many clinicians.<sup>6</sup> We have already described a convenient apparatus for the practical clinical application of the intravenous drip.<sup>7</sup>A central room for the preparation of these intravenous sets was established at the Mount
Symposium: reproduction in baboons. From blastocyst to placenta: the morphology of implantation in the baboon
Authors: Allen C. Enders, Katherine C. Lantz, Pamela E. Peterson, Andrew G. Hendrickx
Journal: Human Reproduction Update (1997)

Implantation and placentation in the baboons share many morphological features with other primates, as well as having some specific distinctions. The ability to use deturgescence of the sex skin as a method of timing ovulation and the ease with which the uterine lumen can be flushed have been used to examine morphological aspects of blastocyst differentiation and implantation in this species. Preimplantation blastocysts were obtained by non-surgical flushing of the uterus 68 days after ovulation, and implantation sites were excised from uteri removed on days 10-16 of gestation. All tissues were prepared for electron microscopy by aldehyde fixation and plastic embedding. Maturation of trophoblast from the compacted morula stage to the expanded blastocyst stage includes increase in numbers of polyribosomes, changes in conformation of mitochondria, and development of an effective endocytic apparatus. An endodermal layer forms beneath the inner cell mass prior to loss of the zona pellucida, and parietal endodermal cells extend beyond the inner cell mass. Azonal blastocysts have regions of syncytial trophoblast adjacent to the inner cell mass, and they may represent adhesion stages of early implantation. In early postimplantation stages, trophoblast replaces the uterine epithelium and processes of syncytial trophoblast invade dilated superficial maternal vessels. In subsequent lacunar stages there is rapid elevation of the developing conceptus above the uterine surface as the lacunae enlarge. Cytotrophoblast rapidly enters maternal vessels, and arterioles are partially or completely occluded by migrating cytotrophoblast. The early access to controlled maternal blood flow apparently allows trophoblastic lacunae to expand superficially as opposed to more extensive endometrial invasion.
Tampons could be used to diagnose sexually transmitted diseases
Authors: Suzanne M Garland, Sepehr N Tabrizi, Christopher K Fairley, Francis J Bowden
Journal: BMJ (2001)

Judicial functions of GMC should be abolishedEditor-Attempts are afoot to turn the General Medical Council into an Alan Milburn quango; hence, it has become necessary for doctors to know what they would be deprived of as a consequence.Currently, the GMC is like a court and is therefore not accountable to ministers or the public.It is a domestic tribunal with the sole purpose of allowing doctors to sit in judgment over other doctors.Therefore, although the Medical Act 1983 makes provision for non-doctors to be on the council, it does not oblige the GMC to give them a judicial role.Also the act ensures that the GMC is fully accountable to doctors.According to schedule 1 of the act, the GMC must first consult individual doctors before it can change the rules governing elections.According to schedule 4 of the act, the GMC must first consult doctors before making any changes to its judicial functions.The act does not even permit the GMC to go directly to the Privy Council to make changes to the constitution without first obtaining a mandate from doctors.The Privy Council itself cannot make changes without prior consultation with the GMC and its constituent doctors.The GMC is
Three-dimensional view of the vascular structure of the lower esophagus in clinical portal hypertension
Authors: Makoto Hashizume, Seigo Kitano, Keizo Sugimachi, Katsuo Sueishi
Journal: Hepatology (1988)

The venous anatomy of the lower esophagus and upper stomach was studied in nine patients with portal hypertension and in five without, following infusion of a silicon rubber compound into vessels of the excised organs within whole tissues made transparent with methyl salicylate. Four venous channels were identified in normal tissues: intraepithelial, subepithelial superficial, deep submucosal and adventitial veins. In portal hypertensive patients, giant esophageal varices formed 2 to 3 cm above the esophagogastric junction fused with numerous superficial and deep submucosal veins. Gastric varices were present in the submucosa where the left gastric venous branch penetrated the gastric wall 2 cm below the esophagogastric junction. The lower esophageal varices were classified into two types of vascular structure: palisading type in five and bar type in four. The palisading type had dilated intraepithelial channels and numerous small superficial collateral veins extending in a longitudinal arrangement. The bar type had triply dilated subepithelial superficial veins and deep submucosal veins which eroded the epithelium, and the gastric varices were present in the latter type. Our study provides evidence of the three-dimensional vascular structure of the lower esophageal varices without the necessity for tissue dissection.
A CASE OF SYMPATHETIC NEURITIS AFTER EVISCERATION OF THE EYEBALL.Read before the Section on Ophthalmology at the Forty-fourth Annual Meeting of the American Medical Association.
Authors: F. C. HOTZ
Journal: JAMA (1893)

Evisceration of the eyeball was introduced by Prof. Graefe in Germany and Dr. Mules in England ten years ago as a substitute for enucleation, for the reason that it was a less dangerous operation and furnished better conditions for the artificial eye. The first report on a larger number of eviscerations performed by Graefe seemed to sustain the favorable opinion of the originators; for among 240 eviscerations there was neither a death nor an instance of sympathetic inflammation after the operation. But soon matters began to take a different aspect. Prof. Schuleck of Budapest, for instance, lost two patients among thirty-six eviscerations in the first week after the operation; and Dr. Cross reported two cases of sympathetic ophthalmitis occurring after evisceration. But as Dr. Cross had inserted a socalled artificial vitreous, it was maintained the sympathetic inflammation in these cases could not be charged to the operation, but was induced
Bone Tumors: General Aspects and Data on 3,987 Cases
Authors: Lester S. King
Journal: JAMA (1967)

This new edition of<i>Bone Tumors</i>will join the select group of texts that every practicing pathologist will want to have available. It is not a textbook, but rather a report of the author's extensive experience with almost 4,000 bone tumors. To the pathologist or clinician it offers a framework to help him evaluate the course and prognosis of his own cases. And where diagnosis is difficult it provides material which can help the pathologist or radiologist reach a decision. Dr. Dahlin employs, essentially, the classification of Lichtenstein. Devoting a chapter to each of 23 specific tumor types, he gives a concise summary of his experience, with each type, including the clinical course, radiologic and pathologic findings, treatment, and prognosis. Helpful charts and outlines indicate for each tumor type the distribution of cases by age and site. The roentgenograms and photomicrographs are of high quality and the references are extremely
The Renal Scintigram in Urologic Work-up
Authors: David M. Sklaroff
Journal: JAMA (1961)

THE DETECTION and assessment of unilateral renal disorders involves a series of complicated diagnostic procedures which add up to a painful, expensive, and time consuming experience for the patient. Consequently, the development of methods for preliminary screening of patients is significant both with regard to the diagnostic information obtained and to the selection of those patients requiring complete urologic work-up. Others may be spared the discomfort of unnecessary examination. In particular, a reliable screening test is important in establishing or ruling out renal pathology as an underlying factor in hypertension. The finding of a disorder of one kidney in the hypertensive patient may be an indication for nephrectomy or other surgical measures. A positive preliminary investigation warrants precise diagnosis by aortography and confirmation by individual renal clearance tests. The primary objective of the screening test is the restriction of more exacting procedures such as aortography, with its inherent risk
Cardiorespiratory Fitness Is Strongly Related to the Metabolic Syndrome in Adolescents
Authors: Ian Janssen, Wendy Cramp
Journal: Diabetes Care (2008)

We respectfully disagree with both issues raised by Shaibi, Cruz, and Goran (1). First, we will address the comment that “associations between fitness and activity are weak at best.” The review article referenced by Shaibi, Cruz, and Goran was based on observational studies published before 1995, a time at which physical activity was measured almost exclusively by questionnaire. Since 1995, several studies have …
Re: Cure of Helicobacter pylori Infection and Duration of Remission in Low-Grade Gastric Mucosa-Associated Lymphoid Tissue Lymphoma
Authors: John F. Seymour
Journal: JNCI Journal of the National Cancer Institute (1998)

ment to determine what evidence is sufficient to present to my patients for their consideration.Limiting my patients' choices to those indications that are economically feasible for a pharmaceutical company to submit to the FDA is neither appropriate nor fair.I am sure that my patient with smallcell carcinoma of the pancreas, who is now in complete remission after chemotherapy with cisplatin and etoposide, could convince Ms. Napoli to understand her error.My Medicare carrier is, unfortunately, a more difficult case, but I am hoping that common sense will prevail.
Im Hexenhaus. Spates Verstehen einer frühinfantil-fixierten Vorstellung
Authors: G.H. Graber
Journal: Psychotherapy and Psychosomatics (1963)

Research Articles| February 10 2010 Im Hexenhaus. Spates Verstehen einer frühinfantil-fixierten Vorstellung Subject Area: Psychiatry and Psychology G.H. Graber G.H. Graber Bern Search for other works by this author on: This Site PubMed Google Scholar Acta Psychotherapeutica et Psychosomatica (1963) 11 (2): 147–153. https://doi.org/10.1159/000285670 Article history Published Online: February 10 2010 Content Tools Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation G.H. Graber; Im Hexenhaus. Spates Verstehen einer frühinfantil-fixierten Vorstellung. Acta Psychotherapeutica et Psychosomatica 1 February 1963; 11 (2): 147–153. https://doi.org/10.1159/000285670 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsActa Psychotherapeutica et Psychosomatica Search Advanced Search Article PDF first page preview Close Modal This content is only available via PDF. 1963Copyright / Drug Dosage / DisclaimerCopyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. You do not currently have access to this content.
Real world data on primary treatment for mantle cell lymphoma: a Nordic Lymphoma Group observational study
Authors: Anna Abrahamsson, Alexandra Albertsson-Lindblad, Peter N. Brown, Stefanie Baumgartner-Wennerholm, Lars M. Pedersen, Francesco D’Amore, Herman Nilsson-Ehle, Paw Jensen, Michael Pedersen, Christian H. Geisler, Mats Jerkeman
Journal: Blood (2014)
479 Significance of HDV-RNA and HBsAg levels in delta hepatitis: First data of the Hep-Net/international HDV intervention trial
Authors: K. Zachou, C. Yurdaydin, H.E. Dienes, G.N. Dalekos, A. Erhardt, Y. Cakaloglu, H. Degertekin, S. Gurel, S. Zeuzem, H. Bozkaya, T. Bock, V. Schlaphoff, M.P. Manns, H. Wedemeyer
Journal: Journal of Hepatology (2006)
Plasma concentrations of lignocaine and prilocaine after a 24-h application of analgesic cream (EMLAR) to leg ulcers
Authors: B. Stymne, S. Lillieborg
Journal: British Journal of Dermatology (2001)

Background Although the lignocaine (lidocaine)–prilocaine cream EMLA® has been extensively studied for the relief of acute treatment-related pain from sharp leg ulcer debridement, no data exist on systemic absorption from prolonged application in patients with chronically painful ulcers. Objectives To study the plasma concentrations of lignocaine and prilocaine resulting from prolonged application of EMLA to leg ulcers. Methods A single 24-h application of 5–10 g (median 6·75) of EMLA was given to 10 patients with painful leg ulcers measuring 50–100 cm2. Venous blood samples, drawn between 0·5 and 27 h after cream application, were analysed by gas chromatography using a nitrogen-sensitive detector. Results The peak plasma levels were in the range 185–705 ng mL−1 and 62–277 ng mL−1 for lignocaine and prilocaine, respectively, and were observed 2–4 h (in one patient 6–8 h) after application. The peak plasma concentration of lignocaine, but not of prilocaine, increased significantly with increasing dose. The cream was well tolerated by the patients. Conclusions The results indicate that a 24-h application of 5–10 g EMLA results in peak plasma concentrations of the two local anaesthetics, which combined are less than one-fifth of those associated with toxic reactions. The analgesic efficacy of EMLA for the relief of chronic ulcer pain deserves further study.