Achalasia in Fraternal Twins
Authors: RICHARD W. NAGLER
Journal: Annals of Internal Medicine (1963)

Case Studies1 December 1963Achalasia in Fraternal TwinsRICHARD W. NAGLER, M.D., RAPHAEL D. SCHWARTZ, M.D., WILLIAM M. STAHL JR., M.D., HOWARD M. SPIRO, M.D., F.A.C.P.RICHARD W. NAGLER, M.D.Search for more papers by this author, RAPHAEL D. SCHWARTZ, M.D.Search for more papers by this author, WILLIAM M. STAHL JR., M.D.Search for more papers by this author, HOWARD M. SPIRO, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-59-6-906 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThis report documents the occurrence of achalasia in fraternal twins and further emphasizes the clinical value of esophageal motility studies in the evaluation of persistent symptoms after cardiomyotomy.CASE 1In November, 1955, a 31-year-old married white man first noted dysphagia; both solids and liquids seemed to stick behind the xiphoid process. Nervous tension did not seem to make the dysphagia worse, There were no other symptoms. He was in good physical condition. X-ray examination showed that the lower esophagus tapered down to a relatively fixed narrowed segment 3 to 4 cm long, with mucosa that appeared to be normal....References1. OLSENHARRINGTONMOERSCHANDERSEN AMSWHJHA: Treatment of cardiospasm: analysis of 12 years experience. J. Thorac. Cardiov. Surg. 22: 164, 1951. Google Scholar2. LEROUXWRIGHT BTJT: Cardiospasm. Brit. J. Surg. 48: 619, 1961. CrossrefMedlineGoogle Scholar3. HELLER E: Extramukose cardiaphastik beim chronischen cardiospasmus mit dilitation des oesophagus. Mitt. Grenzeb. med. chir. 27: 141, 1913-1914. Google Scholar4. FERGUSONBURFORD TBTH: An evaluation of the modified Heller operation in the treatment of achalasia of the esophagus. Ann. Surg. 152: 1, 1960. CrossrefMedlineGoogle Scholar5. KRAMERINGELFINGER PFJ: Ecophageal sensitivity to mecholyl in cardiospasm. Gastroenterology 19: 242, 1951. CrossrefMedlineGoogle Scholar6. BUTINOLSENMOERSCHCODE JWAMHJCF: A study of esophageal pressures in normal persons and patients with cardiospasm. Gastroenterology 23: 278, 1953. CrossrefMedlineGoogle Scholar7. CREAMEROLSENCODE BAMCF: The esophageal sphincters in achalasia of the cardia (cardiospasm). Gastroenterology 33: 293, 1957. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New Haven, ConnecticutFrom the Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.This work was supported in part by grants AM-04759 and AM-05100, United States Public Health Service, Bethesda, Maryland.Requests for reprints should be addressed to Richard W. Nagler, M.D., Department of Internal Medicine, Yale University School of Medicine, New Haven 11, Connecticut. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByAchalasia: will genetic studies provide insights?Achalasia in siblingsDiseases Associated With or Mimicking AchalasiaFamilial coexistence of achalasia and non-achalasic oesophageal dysmotility: evidence for a common pathogenesis.Achalasia Due to Diffuse Esophageal Leiomyomatosis and Inherited as an Autosomal Dominant DisorderSignificant DQw1 association in achalasiaFamilial achalasia in two siblings: Significance of possible hereditary roleFamily occurrence of achalasia and diffuse spasm of the oesophagus.Achalasia in monozygotic twinsDiscordance for achalasia in identical twinsSororal occurrence of diffuse esophageal spasmAchalasiaAchalasia in Mother and DaughterFamilial achalasiaThe EsophagusMedical genetics 1963 1 December 1963Volume 59, Issue 6Page: 906-910KeywordsDizygotic twinsDysphagiaEsophagusMedical servicesMucous membranes Issue Published: 1 December 1963 PDF DownloadLoading ...