tbuckley/cabot-search huggingface dataset:
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Authors: John H. Jackson, Joseph A. Utz, Robert J. Lull, Eugene G. Galvin, John S. Kolina, Daniel A. Boll, Kenneth A. Kaplan, Gottlieb L. Turnbull, Michael D. Redwine
Journal: Clinical Nuclear Medicine (1982)

Jackson, John H.; Utz, Joseph A.; Lull, Robert J.; Galvin, Eugene G.; Kolina, John S.; Boll, Daniel A.; Kaplan, Kenneth A.; Turnbull, Gottlieb L.; Redwine, Michael D. Author Information
1999 Guidelines for Infectious Diseases in Primary Care
Authors: J. V. Hirschmann
Journal: Annals of Internal Medicine (1999)

Medical Writings: Book Notes18 May 19991999 Guidelines for Infectious Diseases in Primary CareJ. V. Hirschmann, MDJ. V. Hirschmann, MDPuget Sound Veterans Affairs Medical Center, University of Washington School of Medicine, Seattle, Washington. (Hirschmann)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-130-10-199905180-00027 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Gorbach SL, Bartlett JG, Falagas M, Hamer DH. 345 pages. Baltimore: Williams & Wilkins; 1999. $24.95. ISBN 0683183435. Order phone 800-638-0672.Field of medicine: Infectious disease.Format: Softcover, pocket-sized book.Audience: Medical students, physicians-in-training, and primary care practitioners seeking a compact guide to infectious diseases.Purpose: To provide guidelines for diagnosing and managing common infections.Content: The first of five sections contains comprehensive outlines of 11 common problems, such as infections of the respiratory, urinary, and gastrointestinal tracts. The end of each chapter contains a brief summary (“practice guidelines”) of important points. The second section consists of much briefer discussions ... Author, Article, and Disclosure InformationAffiliations: Puget Sound Veterans Affairs Medical Center, University of Washington School of Medicine, Seattle, Washington. (Hirschmann) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 18 May 1999Volume 130, Issue 10Page: 866-867KeywordsAntimicrobialsEndocarditisInfectious diseasesMeningitisOsteomyelitisOutpatientsProphylaxisRespiratory infectionsUpper respiratory tract infectionsUrinary tract infections ePublished: 15 August 2000 Issue Published: 18 May 1999 Copyright & PermissionsCopyright © 1999 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
De subitaneis mortibus. X. Familial congential heart block.
Authors: T N James, R C McKone, A S Hudspeth
Journal: Circulation (1975)

Complete heart block was found shortly after birth in a brother and sister (not twins). Both were treated by electronic pacing because of symptoms attributable to inadequate cardiac output and electrical instability of heart. The boy has done well with his artificial pacemaker and is now six years old. His sister died of complications due in part to the large size of her pacemaker and small size of her body. At necropsy special studies of her heart included the centers for normal impulse formation and concuction. The primary abnormalities were at the junction of atrial septum with atrioventricular (A-V) node, and at the origin of the two bundle branches from the His bundle. The A-V node was isolated by collagen at all its margins except its junction with the His bundle. The proximal His bundle was essentially normal, but from that point on through the initial protions of both the left and right bundle branches there was extensive caseous degeneration which interrupted any possible conduction. These findings are discussed in relation to fetal and postnatal development of the human A-V node, and the His bundle and its branches; and in the context of a recently observed mathematical relationship between sinus rate and two forms of experimentally produced A-V junctional escape rhythms.
A CASE OF PERSISTENT SPASM OF THE ACCOMMODATION, RELIEVED TEMPORARILY BY TENOTOMY OF THE EXTERNAL RECTI.Read in the Section on Ophthalmology, at the Forty-fourth Annual Meeting of the American Medical Association.
Authors: ALBERT RUFUS BAKER
Journal: JAMA (1893)

Miss P., aged 39, at the age of 33 began to suffer from headache, pain in eyes when reading. In a few months was obliged to give up reading and using the eyes altogether. Was treated by various physicians for nervous prostration, neuralgia, etc. Finally advised to seek a change of climate. A residence of several years in the West proving of no benefit she returned East for treatment. In May, 1892, she came under my care. Family history good and her own health had always been good until the present trouble. She is fairly well nourished, appetite good, bowels regular, sleeps well and no menstrual trouble or other difficulty. Says she would be well if she could get relief from constant headache and pain in eyes when using them. Headaches mostly occipital but much pain referred to temples and vertex. Upon examination, I found vision right eye 20-20, not
Tc-99m DEXTRAN
Authors: Eberhard Henze, Heinrich R. Schelbert, Leslie R. Bennett, James D. Collins, Ahmad Najafi, David E. Kuhl
Journal: Clinical Nuclear Medicine (1981)

Henze, Eberhard; Schelbert, Heinrich R.; Bennett, Leslie R.; Collins, James D.; Najafi, Ahmad; Kuhl, David E. Author Information
Cardiac Arrhythmias: The Modern Electrophysiological Approach
Authors: Massimo Calabresi
Journal: JAMA (1976)

This volume comprises 11 essays on selected topics of modern cardiac electrophysiology. One purpose of the book was to present in English some important recent contributions of investigators who have published their work chiefly in other languages. Some chapters are devoted primarily to technology, others to general physiology, normal and pathological anatomy, or pharmacology; still others report results of modern methods of investigation in selected arrhythmias. These investigations permit, at least in some cases, exact definition of the pathogenesis and origin of the abnormal impulses—macroreentry, microreentry, or ectopic focal pacemaker. The localization of the abnormal mechanism of stimulation may be precise enough to contemplate surgery in uncommon cases of arrhythmias that endanger life and resist medical therapy. The quality of these papers is good. Generally well-written, they present factual information, largely but not exclusively derived from personal experience. The obvious enthusiasm of the investigators is balanced by sound criticism; frequently
CD: Interactive Skeleton: Kinetic and Sports Edition
Authors: D. MacAuley
Journal: BMJ (2000)

Peter H Abrahams, Jeffrey M Anderson, Derek Field Primal Pictures, £60 ISBN 1 90247 0079 Rating: ![Graphic][1]</img>![Graphic][2]</img> The all singing, all dancing virtual teaching partner. Just place the genie in the CD player and every anatomical, physiological, myological, and educational need should be satisfied. The cover blurb promised the world's finest complete CD skeleton, and I loaded up with enthusiasm. Sports and kinetic edition—just what I need. Picture the scene in the consulting room, the doctor searching through an overflowing drawer of photographs, drug company illustrations, … [1]: /embed/inline-graphic-1.gif [2]: /embed/inline-graphic-2.gif
Penicillin Treatment of Streptococcal Pharyngitis
Authors: Irving S. Colcher
Journal: JAMA (1972)

Of 300 children with streptococcal pharyngitis, one group received a mixture of penicillin G procaine and penicillin G benzathine; a second was given a prescription for ten days of penicillin phenoxymethyl (parents of this group were given no special instructions); and a third was given identical prescriptions but their parents received specific counseling on the importance of taking the medication. There were 14 treatment failures plus relapse in group 1, 25 in group 2, and 10 in group 3. Compliance in taking penicillin was 58% in group 2 and 80% in group 3, a significant difference. Oral therapy with adequate parental counseling is as efficacious as intramuscular injection.
Effect of Chemotherapy on Infectiousness of Tuberculosis
Authors: Joseph H. Bates, William W. Stead
Journal: New England Journal of Medicine (1974)

Today, tuberculous patients are being treated widely in general hospitals and at home rather than being isolated from society in special sanatoriums. Often, they are discharged from the hospital while tubercle bacilli can still be easily identified in their sputum. This practice has generated considerable concern in some quarters that tuberculosis might thereby be transmitted to unsuspecting persons.An understanding of the transmission of tuberculosis among human beings was slow to evolve, and practices were based largely on fallacious conclusions derived from studies of the problem among nursing and medical students from 1920 to 1940.1 It appeared that tuberculosis must . . .
Fertility doctors are urged to treat foreign patients equitably
Authors: A. Gulland
Journal: BMJ (2011)

The growing number of patients travelling abroad for fertility treatment has prompted new guidelines on cross border care.

The European Society of Human Reproduction and Embryology guidelines say that the care of foreign and local patients should be the same and should be to the best possible standards, but “there is evidence that this is not always the case” ( Human Reproduction doi:10.1093/humrep/der090).

The guidelines state that foreign and local patients should be subject to similar protocols and fees and that the same information, counselling, and psychological support should be …
Myocardial Infarction Associated with Pregnancy
Authors: Alan Brown
Journal: New England Journal of Medicine (1960)

THE incidence of heart disease in pregnant women is approximately 2 per cent. Rheumatic heart disease makes up the vast preponderance of these cases, whereas myocardial infarction is rare. The purpose of this paper is to review the reported cases of myocardial infarction associated with pregnancy and to report 2 additional cases.Review of the LiteratureIn 1952 Mendelson1 reviewed 19 case reports from 1871 to 1950, and added 4 cases of his own. In the ensuing eight years 25 more cases have been noted,2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 bringing the total to 48. Of these, only 221 2 3 4 5 6 7 8 9 10 11 12 13 , 21 22 23 24 present acceptable evidence for the diagnosis . . .
Endothelin and mechanical properties of the carotid artery in Wistar–Kyoto and spontaneously hypertensive rats
Authors: Giuseppe Marano, Mauro Grigioni, Sergio Palazzesi, Alberto U Ferrari
Journal: Cardiovascular Research (1999)

The aim of this study is to evaluate the role of endothelin in the control of the static mechanical properties of in vitro carotid arteries from 14-week-old Wistar–Kyoto (WKY) and spontaneously hypertensive rats (SHR). An in vitro preparation in which the artery was allowed to longitudinally elongate similarly to the in situ carotid artery was employed. The diameter of in vitro carotid arteries subjected to static pressures (from 25 to 200 mmHg in 25 mmHg steps) was determined by videomicroscopy and computer-assisted image analysis, the cross-sectional compliance– and distensibility–pressure curves being then derived. The role of endothelin was assessed by incubating carotid arteries with the selective ETA and ETB endothelin receptor antagonists BQ123 and BQ788, respectively. These effects were compared with those observed under control conditions, as well as with those following complete abolition of vascular smooth muscle tone by potassium cyanide (KCN). Carotid diameter was significantly larger, and compliance and distensibility significantly smaller, in SHR compared to WKY rats. Local incubation with BQ123 was associated with significant dilations as well as significant increases in cross-sectional compliance and distensibility in both strains. This was even more pronounced with KCN, while BQ788 had no effect. The results of the present study suggest that: (i) endothelin exerts a tonic stiffening effect on the in vitro common carotid artery; (ii) this effect is mediated via the ETA endothelin receptor, and (iii) the stiffening effect of endothelin is exerted to a similar extent in the carotid arteries of normotensive WKY and SHR rats.
Interferon response to dipyridamole in lupus erythematosus patients
Authors: K. KONSTANTINOV, A. GALABOV, M. MASTIKOVA
Journal: British Journal of Dermatology (1989)

Studies in patients with autoimmune disorders strongly support a role for interferon (IFN) in the disease process. In the present study we investigated the in vivo production of α‐IFN in lupus erythematosus patients after stimulation with dipyridamole, recently characterized as an α‐IFN inducer in mice and humans. Levels of IFN were measured in serum samples from 22 patients with systemic lupus erythematosus (SLE) and 12 patients with discoid lupus erythematosus (DLE) before and 24 h after dipyridamole administration. IFN activity was assayed on human and bovine cells in parallel. Initial serum concentrations of α‐IFN in SLE patients were markedly elevated. The percentage of DLE positive responders to dipyridamole induction was about twice as high as that found for SLE. Studies of factors responsible for IFN production in lupus erythematosus might result in better understanding of the relationship between DLE and SLE.
Alteration of pulmonary immunity to Listeria monocytogenes by diesel exhaust particles (DEPs). II. Effects of DEPs on T-cell-mediated immune responses in rats.
Authors: Xue-Jun Yin, Rosana Schafer, Jane Y C Ma, James M Antonini, Jenny R Roberts, David N Weissman, Paul D Siegel, Joseph K H Ma
Journal: Environmental Health Perspectives (2003)

Previously, we showed that diesel exhaust particles (DEPs) suppressed pulmonary clearance of Listeria monocytogenes (Listeria) and inhibited the phagocytosis of alveolar macrophages and their response to Listeria in the secretion of interleukin (IL)-1 beta, tumor necrosis factor alpha, and IL-12. In this report we examined the effects of DEPs and/or Listeria on T-cell development and secretion of IL-2, IL-6, and interferon (IFN)-gamma. We exposed Brown Norway rats to clean air or DEPs at 50 or 100 mg/m3 for 4 hr by nose-only inhalation and inoculated with 100,000 Listeria. Lymphocytes in the lung-draining lymph nodes were isolated at 3 and 7 days postexposure, analyzed for CD4+ and CD8+ cells, and measured for cytokine production in response to concanavalin A or heat-killed L. monocytogenes. Listeria infection induced lymphocyte production of IL-6. At 7 days postinfection, lymphocytes from Listeria-infected rats showed significant increases in CD4+ and CD8+ cell counts and the CD8+/CD4+ ratio and exhibited increased production of IFN-gamma and IL-2 receptor expression compared with the noninfected control. These results suggest an immune response that involves the action of IL-6 on T-cell activation, yielding Listeria-specific CD8+ cells. DEP exposure alone enhanced lymphocyte production of both IL-2 and IL-6 but inhibited lymphocyte secretion of IFN-gamma. In rats exposed to 100 mg/m3 DEPs and Listeria, a 10-fold increase occurred in pulmonary bacterial count at 3 days postinfection when compared with the Listeria-only exposure group. The isolated lymphocytes showed a significant increase in the CD4+ and CD8+ cell counts and the CD8+/CD4+ ratio and exhibited increased IL-2 responsiveness and increased capacity in the secretion of IL-2, IL-6, and IFN-gamma. This T-cell immune response was sufficient to allow the Brown Norway rats to clear the bacteria at 7 days postinfection and overcome the down-regulation of the innate immunity by the acute DEP exposure.
THE TREATMENT OF DYSENTERY CASES IN STATE INSTITUTIONS
Authors: HENRY A. JONES
Journal: JAMA (1913)

In August and September dysentery makes its appearance, and is quite apt to be epidemic in prisons, jails, almshouses, asylums and other state institutions. When epidemic the disease is found in all its forms, from the cases of loose, frequent mucous stools to the scraped-meat, bloody dejections. The latter cases are usually found in the demented, who are as a general much debilitated, and in the aged, whose assimilative and recuperative powers are low, and whose arteriosclerosis extends not only to the radial and temporal arteries, but to the finer vessels which supply the intestinal viscera. In cases of marked arteriosclerosis stupor is a prominent symptom, and the usual remedies do not appear to be of the slightest benefit. In treating this disease during the past few years, I have exhausted the Pharmacopeia, going through the list of drugs from Squibb's diarrhea mixture to the many others opium formulas.
Electronic Documentation in Endoscopy: Present Status and Future Perspectives from a Company Standpoint
Authors: W. Teuffel, J. Stettin
Journal: Endoscopy (2001)

At the beginning of the development of endoscopic information systems all companies were technology-oriented. Today, we see a change from technology to content orientation, the same development which is seen in internet technology. In future systems, it will not be the software that makes a difference but the contents. Contents means not only patient data but also algorithms for feature extraction within large databases with reference images, for example [20]. The automatic recognition of features, such as a complication rate that is too high or a correlation of a certain disease with an endoscopic finding, will be part of a content-based approach. It means that content will also be the knowledge base which has to be developed for future systems. The system of the future will be much more intelligent and less software technology-oriented.
Red ink tattoo reactions: successful treatment with the Q-switched 532 nm Nd:YAG laser
Authors: F.C. Antony, C.C. Harland
Journal: British Journal of Dermatology (2003)

Journal Article Red ink tattoo reactions: successful treatment with the Q‐switched 532 nm Nd:YAG laser Get access F.C. Antony, F.C. Antony Department of Dermatology, St Helier Hospital, Carshalton, Surrey, SM5 1AA, U.K Dr F.C.Antony. E‐mail: fiantony@hotmail.com Search for other works by this author on: Oxford Academic Google Scholar C.C. Harland C.C. Harland Department of Dermatology, St Helier Hospital, Carshalton, Surrey, SM5 1AA, U.K Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 149, Issue 1, 1 July 2003, Pages 94–98, https://doi.org/10.1046/j.1365-2133.2003.05342.x Published: 01 July 2003 Article history Accepted: 17 November 2002 Published: 01 July 2003
Enhancement of platelet aggregation by tranylcypromine in mouse cerebral microvessels.
Authors: W I Rosenblum, F El-Sabban
Journal: Circulation Research (1978)

Tranylcypromine, given intraperitoneally at doses greater than or equal to 10 mg/kg, enhanced platelet aggregation in the arterioles on the cerebral surface in mice. Tranylcypromine inhibits prostacyclin synthesis in vitro. Iproniazid, which inhibits monoamine oxidase but not prostacyclin synthesis, failed to enhance platelet aggregation. The failure of iproniazid to enhance aggregation in this study rules out an effect on monoamine oxidase as the cause of tranylcypromine's action. That iproniazid inhibited aggregation indicates it has an effect opposite to that of tranylcypromine. Imidazole, a drug known to inhibit synthesis of both prostacyclin and thromboxane, failed to affect platelet aggregation. All of our data are compatible with the hypothesis that prostacyclin is an inhibitor of platelet aggregation. This hypothesis has been based largely on in vitro data, to which we now add in vivo support.
EXCISION OF BARTHOLIN GLAND CYSTS
Authors: A. J. Gordon
Journal: JAMA (1928)

<h3>To the Editor:</h3> —InThe Journal, Dec. 31, 1927, Dr. G. H. Taubles of San Francisco describes a technic for excision of Bartholin gland cysts by the injection of melted paraffin to facilitate the dissection. This method has been employed by me for several years. This procedure is not at all new, being originated first by Pozzi and quoted by Crossen in the fourth edition of "Diseases of Women."
Medical fiction could be misleading
Authors: R. Manfredini
Journal: BMJ (1999)

EDITOR—Medical fiction series undoubtedly have a deep impact on people. As mentioned by Collee, millions of viewers are so dependent on television that it has become their main source of information.1 Though some concern may result from the possibility of encouraging harmful behaviour, as discussed by Hawton et al,2 there are other medical issues.

As a professor of emergency medicine, I know very well the everyday reality of emergency physicians. I agree with Collee: “If things …
Disease awareness campaigns turn healthy people into patients
Authors: Owen Dyer
Journal: BMJ (2006)

Media and advertising campaigns that apparently aim at increasing public awareness of underdiagnosed illnesses are really marketing tools for drug companies in search of new customers, say a group of authors and researchers who met in Australia this week for a conference on “disease mongering.”

The conference on disease mongering, held in Newcastle, Australia, was timed to coincide with a theme issue of the journal PLoS Medicine , published by the US Public Library of Science (PLoS).

April's issue of PloS Medicine carries 11 peer reviewed articles on disease mongering, which is defined by this month's guest editors as “the …
Minimising blood loss in caesarean section.
Authors: M Kenny
Journal: BMJ (1975)

among the most significant advances in the medical treatment of these conditions in the history of medicine.These facts must be weighed against the extremely rare instances of these relatively minor epidermal reactions.Rashes are not infrequent in hypertensive patients taking methyldopa, while 1 in 5 patients treated with the latter develop a positive Coombs test and 1 in 500 go on to develop haemolytic anaemia.5Such features have occasioned less comment than the development of this rare and usually reversible oculo- cutaneous syndrome in patients on treatment with beta-blocking drugs.We are appreciative of the professional advice offered in this case by Mr B Martin.
Failure of Exogenous TSH to Stimulate Suppressed Tissue in a Case of Toxic Adenoma
Authors: N F KHAMMASH, R K HALKAR
Journal: Clinical Nuclear Medicine (1989)

A standard TSH stimulation procedure that failed to stimulate suppressed thyroid tissue in a case of toxic adenoma is described. After radioiodine treatment, when the patient became hypothyroid, a repeat thyroid scan showed tracer concentration in the rest of the gland.
Fabrication and biocompatibility of polypyrrole implants suitable for neural prosthetics
Authors: Paul M. George, Alvin W. Lyckman, David A. LaVan, Anita Hegde, Yuika Leung, Rupali Avasare, Chris Testa, Phillip M. Alexander, Robert Langer, Mriganka Sur
Journal: Biomaterials (2004)
Blood Lead and Blood Pressure
Authors: William R. Harlan
Journal: JAMA (1985)

Heavy lead exposure has been connected to cardiovascular disease, but modest exposures encountered in the general environment have not been associated previously with disease risk. The relationship between blood lead levels and blood pressures was examined using data from the second National Health and Nutrition Examination Survey. A direct relationship was found between blood lead levels and systolic and diastolic pressures for men and women and for white and black persons aged 12 to 74 years. Blood lead levels were significantly higher in younger men and women (aged 21 to 55 years) with high blood pressure, but not in older men or women (aged 56 to 74 years). In multiple regression analyses, the relationship of blood lead to blood pressure was independent of other variables for men, but not for women. Dietary calcium and serum zinc levels were inversely related to blood pressure. (<i>JAMA</i>1985;253:530-534)