Q FEVER ASSOCIATED WITH GRANULOMATOUS HEPATITIS
Authors: J PICCHI, A R NELSON, E E WALLER, M RAZAVI, E E CLIZER
Journal: Annals of Internal Medicine (1960)

Case Reports1 November 1960Q FEVER ASSOCIATED WITH GRANULOMATOUS HEPATITISJOSEPH PICCHI, M.D., ALAN R. NELSON, M.D., EDWARD E. WALLER, M.D., MOHAMAD RAZAVI, M.D., EDWIN E. CLIZER, M.D.JOSEPH PICCHI, M.D.Search for more papers by this author, ALAN R. NELSON, M.D.Search for more papers by this author, EDWARD E. WALLER, M.D.Search for more papers by this author, MOHAMAD RAZAVI, M.D.Search for more papers by this author, EDWIN E. CLIZER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-53-5-1065 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptQ fever is an acute febrile disease with systemic manifestations, caused by the rickettsiaCoxiella burnetii, and usually transmitted by inhalation, without an intermediate vector. It has now been reported throughout the world, and is endemic in many parts of the United States, especially California. Emphasis is usually placed on the pulmonary aspects of the disease; however, we are reporting three cases of Q fever that came under our care during a recent epidemic in Alameda County, each presenting as hepatitis with inconspicuous or absent pulmonary findings. Liver biopsy in all three cases demonstrated a diffuse granulomatous process with multinucleated...Bibliography1. Derrick EH: "Q" fever, a new fever entity: clinical features, diagnosis and laboratory investigation, M. J. Australia 2: 281, 1937. CrossrefGoogle Scholar2. ClarkLennetteRailsbackRomer WHEHOCMS: Q fever in California. VII. Clinical features in 180 cases, Arch. Int. Med. 88: 155, 1951. CrossrefGoogle Scholar3. Rivers TM: Viral and rickettsial infections of man, 3rd Ed., 1959, J. B. Lippincott Co., Philadelphia. Google Scholar4. Perrin TL: Histopathologic observations in a fatal case of Q fever, Arch. Path. 47: 361, 1949. Google Scholar5. GerstlMovittSkahen BERJR: Liver function and morphology in Q fever, Gastroenterology 30: 813, 1956. CrossrefMedlineGoogle Scholar6. ShumanGalloway CRJA: Q fever with liver involvement, Pennsylvania M. J. 61: 10, 1958. Google Scholar7. HurwitzMcLaughlin GKJC: Q fever manifested by anemia and hepatitis, California Med. 90: 3, 1959. Google Scholar8. PopperSchaffner HF: Liver: structure and function, 1957, McGraw-Hill, New York. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Oakland, California*Received for publication January 25, 1960.From the Department of Medicine, Highland-Alameda County Hospital, Oakland, California.Requests for reprints should be addressed to Joseph Picchi, M.D., Highland-Alameda County Hospital, 2701 Fourteenth Avenue, Oakland 6, California. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byBacterial infections and the liverCoxiella burnetii serology in granulomatous hepatitisHepatic fibrin-ring granulomas in a patient with hepatitis AExperimental model for dermal granulomatous hypersensitivity in Q feverQ Fever HepatitisAtypical PneumoniasGranulomatous hepatitis in Q feverClinical Utilization of Alkaline Phosphatase MeasurementsActivation of guinea pig macrophages by Q fever rickettsiaeTumor regression with Q fever rickettsiae and a mycobacterial glycolipidThe liver in boutonneuse feverSyndromes cliniques non classiques provoqués par des rickettsies et des agents prochesTransmission of Q fever from experimental sheep to laboratory personnelQ Fever HepatitisH. L. DUPONT, M.D., R. B. HORNICK, M.D., F.A.C.P., H. S. LEVIN, M.D., M. I. RAPOPORT, M.D., T. E. WOODWARD, M.D., F.A.C.P.The Clinical Use of ChloramphenicolBacterial infections and the liverGranulomatous Hepatitis An Analysis of 63 Cases and Review of the LiteratureJAMES C. GUCKIAN, M.D., JOHN E. PERRY, M.D.RickettsienQ-FieberQ fever and infectious hepatitis 1 November 1960Volume 53, Issue 5Page: 1065-1074KeywordsHepatitisHepatitis AHospital medicineInhalationLiverPhosphatasesPulmonary diseasesQ feverRickettsiaSystemic diseases ePublished: 1 December 2008 Issue Published: 1 November 1960 PDF downloadLoading ...