Penicillin-Resistant Pneumococcus and Meningitis
Authors: Gregory M. Caputo, Fred R. Sattler, Michael R. Jacobs, Peter C. Appelbaum
Journal: Annals of Internal Medicine (1983)

Letters and Corrections1 March 1983Penicillin-Resistant Pneumococcus and MeningitisGREGORY M. CAPUTO, M.D., FRED R. SATTLER, M.D., MICHAEL R. JACOBS, M.D., PH.D., PETER C. APPELBAUM, M.D., PH.D.GREGORY M. CAPUTO, M.D.Search for more papers by this author, FRED R. SATTLER, M.D.Search for more papers by this author, MICHAEL R. JACOBS, M.D., PH.D.Search for more papers by this author, PETER C. APPELBAUM, M.D., PH.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-98-3-416_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Isolates of Streptococcus pneumoniae either relatively resistant (minimal inhibitory concentration, 0.1 to 1.0 µg/mL) or fully resistant to penicillin (4 to 8 µg/mL) have been identified throughout the world (1, 2). In the United States, meningitis due to such strains have been limited to a few cases in children. This report describes, we believe, the first case in an adult.A 68-year-old woman was admitted from a nursing home because she had temperatures up to 40°C and increasing confusion of 2 days' duration. Her neck was stiff, and she did not respond to painful stimuli. A lumbar...References1. HANSMANBULLEN DM. A resistant pneumococcus. Lancet. 1967;2:264-5. CrossrefGoogle Scholar2. APPELBAUMBHAMJEESCRAGGHALLETTBOWENCOOPER PAJAAR. Streptococcus pneumoniae resistant to penicillin and chloramphenicol. Lancet. 1977;2:995-7. CrossrefMedlineGoogle Scholar3. JACOBSGASPARROBINS-BROWNEKOORNHOF MMRH. Antimicrobial susceptibility testing of pneumococci: II. Determination of optimal disk diffusion test for detection of penicillin G resistance. J Antimicrob Chemother. 1980;6:53-64. CrossrefMedlineGoogle Scholar4. TWEARDYJACOBSSPECK DMW. Susceptibility of penicillin resistant pneumococci to new β-lactam antibiotics. In: Program and Abstracts of the 21st Interscience Conference of Antimicrobial Agents and Chemotherapy. Washington, DC: American Society for Microbiology; 1981. (Abstract 501). Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: The Milton S. Hershey Medical Center The Pennsylvania State University College of Medicine Hershey, PA 17033 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByImpact of Antibiotic Resistance on Chemotherapy for Pneumococcal InfectionsDonnées épidémiologiques de la résistance aux antibiotiques des pneumocoques isolés du LCRTraitement antibiotique des méningites purulentes de l'adulteMéningite à pneumocoque résistant à la pénicilline et transmission nosocomiale en milieu hospitalier pédiatrique confirmée par analyse génomiqueManagement of meningitis caused by penicillin-resistant Streptococcus pneumoniaeIn vivo activity and pharmacodynamics of cefotaxime or ceftriaxone in combination with fosfomycin in fibrin clots infected with highly penicillin-resistant Streptococcus pneumoniaeInfections due to antibiotic-resistant gram-positive cocciFailure of chloramphenicol therapy in penicillin-resistant pneumococcal meningitisThe Management of Central Nervous System InfectionsOrientations du traitement antibiotique dans les infections pneumococciques broncho-pulmonaires et méningées avec le développement des souches résistantes à la pénicilline GCharacteristics and antibiotic therapy of adult meningitis due to penicillin-resistant pneumococciANTIBIOTIC THERAPY—A RESUMEWorld-wide development of antibiotic resistance in pneumococciRisk Factors and Response to Antibiotic Therapy in Adults with Bacteremic Pneumonia Caused by Penicillin-Resistant PneumococciAntibiotic resistance and serotypes of 100 Streptococcus pneumoniae strains isolated in a children's hospital in Barcelona, SpainPenicillin-resistantStreptococcus pneumoniae meningitis successfully treated with vancomycin 1 March 1983Volume 98, Issue 3Page: 416-417KeywordsAttentionChildrenMeningitisNursing homesPenicillinPneumococcusPneumoniaStreptococcusTemperature Issue Published: 1 March 1983 PDF DownloadLoading ...