IRON METABOLISM: CLINICAL EVALUATION OF IRON STORES
Authors: A R STEVENS, D H COLEMAN, C A FINCH
Journal: Annals of Internal Medicine (1953)

Article1 February 1953IRON METABOLISM: CLINICAL EVALUATION OF IRON STORESALEXANDER R. STEVENS JR., DANIEL H. COLEMAN, CLEMENT A. FINCHALEXANDER R. STEVENS JR.Search for more papers by this author, DANIEL H. COLEMANSearch for more papers by this author, CLEMENT A. FINCHSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-38-2-199 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn 1948 Rath and Finch1 described a simple method for the estimation of the iron stores in man by examining an unstained smear of bone marrow aspirate. In the present paper the method is applied to a large cross section of hematologic problems. The data obtained indicate that marrow examination for hemosiderin is a reliable index of iron stores in man and is frequently the decisive test in the diagnosis of anemia due to iron deficiency.MATERIAL AND METHODSTwo hundred ninety-eight marrow examinations were made on consecutive patients at the King County Hospital referred for hematologic evaluation between September,...Bibliography1. RathFinch CECA: Sternal marrow hemosiderin, J. Lab. and Clin. Med. 33: 81-86, 1948. MedlineGoogle Scholar2. ShodenFinch NACA: Unpublished data. Google Scholar3. HaskinsStevensFinchFinch DARSCA: Iron metabolism. Iron stores in man as measured by phlebotomy, J. Clin. Investigation 31: 543-547, 1952. CrossrefMedlineGoogle Scholar4. MasshoffGruner WP: Das Eisen im punktierten Knochenmark, Acta Haematologica 5: 19-29, 1951. CrossrefMedlineGoogle Scholar5. Hagen PS : Personal communication. Google Scholar6. FinchHaskinsFinch SDCA: Iron metabolism. Hematopoiesis following phlebotomy. Iron as a limiting factor, J. Clin. Investigation 29: 1078-1086, 1950. CrossrefMedlineGoogle Scholar7. FinchHegstedKinneyThomasRathHaskinsFinchFluharty CAMTDEDCEDSRG: Iron metabolism. The pathophysiology of iron storage, Blood 5: 983-1008, 1950. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Seattle, Washington*Received for publication September 23, 1952.From the Department of Medicine, University of Washington School of Medicine.These studies were supported by grants-in-aid from the United States Public Health Service and the Atomic Energy Commission. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byA study of Iron store in Bone marrow and its correlation in various anemiaIronSerum ferritin values in Nigerian pregnant womenAnemia of chronic diseaseIronIronIron Deficiency Anaemia in a Rural Area in NigeriaSerum ferritin as a measure of iron stores in normal subjectsIron Deficiency in Patients with Chronic Obstructive Airways DiseaseMegaloblastic anemia associated with erythroid hypoplasiaAVAILABILITY OF IRON STORES BUILT UP BY IRON DEXTRINThe evolution of anemia in alcoholic patientsEstimation of iron in human bone marrow with histological, chemical and neutron activation analysisNormalbereich der intestinalen Eisenresorption bei Neugeborenen und S�uglingenDiagnostic Value of Marrow Hemosiderin PatternsROBERT K. NIXON, M.D., F.A.C.P., JOHN P. OLSON, M.D.MOBILISATION OF IRON IN PREGNANCYDepoteisen im KnochenmarkMarrow Iron An Evaluation of Depleted Stores in a Series of 1,332 Needle BiopsiesL. D. ELLIS, M.D., W. N. JENSEN, M.D., F.A.C.P., M. P. WESTERMAN, M.D.Comparison of Hemosiderin Estimation in Bone Marrow Sections and Bone Marrow SmearsReferencesUse of the Prussian Blue Reaction in the Differential Diagnosis of AnemiasWARREN D. BOWMAN JR., M.D.Further Studies on the Interrelationship between Hemosiderin and Sideroblasts in Bone Marrow SmearsHemosiderin Estimations and Sideroblast Counts in the Differential Diagnosis of Iron Deficiency and other AnemiasA COMPARISON OF THE PLASMA IRON, IRON-BINDING CAPACITY, STERNAL MARROW IRON AND OTHER METHODS IN THE CLINICAL EVALUATION OF IRON STORES*E. BEUTLER, M.D., M. J. ROBSON, B.S., E. BUTTENWIESER, B.S.Comparison of the ‘Iron Absorption Test’ with the Determination of the Iron-Binding Capacity of Serum in the Diagnosis of Iron DeficiencyTreatment of iron deficiency anemia in the adultClinical Evaluation of Iron StoresThe Diagnosis and Treatment of Iron-Deficiency AnemiaMechanisms of Anemia in CancerIRONDie Bedeutung der Knochenmarksuntersuchung f�r die Diagnose der An�mien in der Geburtshilfe 1 February 1953Volume 38, Issue 2Page: 199-205KeywordsBone marrowHematologic testsIron deficiencyIron deficiency anemiaMedical services ePublished: 1 December 2008 Issue Published: 1 February 1953 PDF downloadLoading ...