GASTRIC CANCER ON ULCER: A CLINICAL ANALYSIS OF A SERIES OF CASES CONFORMING PATHOLOGICALLY TO THE CRITERIA FOR MALIGNANT CHANGE IN PEPTIC ULCER OF THE STOMACH
Authors: T R WAUGH, M D CHARENDOFF
Journal: Annals of Internal Medicine (1952)

Article1 September 1952GASTRIC CANCER ON ULCER: A CLINICAL ANALYSIS OF A SERIES OF CASES CONFORMING PATHOLOGICALLY TO THE CRITERIA FOR MALIGNANT CHANGE IN PEPTIC ULCER OF THE STOMACHTHEO. R. WAUGH, M.D., MORRIS D. CHARENDOFF, M.D.THEO. R. WAUGH, M.D.Search for more papers by this author, MORRIS D. CHARENDOFF, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-37-3-534 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe incidence of the development of malignancy in a chronic peptic ulcer of the stomach has been a controversial subject among internists, surgeons and pathologists for many years. An extraordinary and in fact incredible difference of opinion is reported in the medical literature. Wilson and MacCarty in 190914stated that 71 per cent of apparently benign peptic ulcerations in this organ on careful microscopic examination showed carcinoma. Newcomb,11on the basis of strict criteria, found that 13 per cent of cancers showed evidence of an antecedent peptic ulcer, and that 3 to 7 per cent of peptic ulcers revealed malignant...Bibliography1. Askanazy M: Über Bau und Entstehung des chronischen Magengeschwürs sowie Soopilzbefunde in ihm, Virchows Arch. f. path. Anat. 234: 111, 1921; 250: 370, 1924. CrossrefGoogle Scholar2. BorrmannHenkeLubarsch RFO: Handbuch der speziellen pathologischen Anatomie und Histologie, 1926, Julius Springer, Berlin, IV, 812. Google Scholar3. Bowen JT: Precancerous dermatoses, J. Cutan. Dis. 30: 241, 1912. Google Scholar4. Boyd W: Surgical pathology, 1946, W. B. Saunders, Philadelphia. Google Scholar5. Broders AC: Carcinoma in situ contrasted with benign penetrating epithelium, J. A. M. A. 99: 1670, 1932. CrossrefGoogle Scholar6. Ewing J: Neoplastic diseases, 1930, W. B. Saunders Company, Philadelphia. Google Scholar7. Herbut PA: Surgical pathology, 1948, Lea & Febiger, Philadelphia. Google Scholar8. HertigSommersBengloff ATSCH: Genesis of endometrial carcinoma. III. Carcinoma in situ, Cancer 2: 964, 1949. CrossrefMedlineGoogle Scholar9. Kiernan PC: Gastric ulcer and its relation to malignancy, S. Clin. North America 30: 1743, 1950. CrossrefMedlineGoogle Scholar10. Mallory TB: Carcinoma in situ of the stomach and its bearing on the histogenesis of malignant ulcers, Arch. Path. 30: 348, 1940. Google Scholar11. Newcomb WD: The relationship between peptic ulceration and gastric carcinoma, Brit. J. Surg. 20: 279, 1932-33. CrossrefGoogle Scholar12. Pack GT, Moderator: Panel Discussion, The relationship of gastric cancer, Cancer 3: 515, 1950. CrossrefMedlineGoogle Scholar13. Schiller W: Untersuchungen zur Entstehung der Geschwülste. 1 Teil: Collum carcinoma des Uterus, Virchows Arch. f. path. Anat. 263: 279, 1927. CrossrefGoogle Scholar14. WilsonMacCarty LBWC: The pathological relationship of gastric carcinoma, Am. J. M. Sc. 138: 846, 1909. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Montreal, Canada*Received for publication March 17, 1952.From the Department of Pathology, Division of Surgical Pathology, McGill University, Montreal. Case histories were made available through the courtesy of the Department of Surgery, Royal Victoria Hospital, and Dr. Harold S. Hooper, Grand'Mere, Quebec. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byGastrointestinal Ulcers and CancerCARCINOMA OF THE STOMACH*CHARLES A. FLOOD, M.D., F.A.C.P.BENIGN ULCER AND CARCINOMA OF THE STOMACH 1 September 1952Volume 37, Issue 3Page: 534-542KeywordsGastric cancerGastric ulcersPathologistsPeptic ulcersStomachSurgeonsSurgerySurgical pathology ePublished: 1 December 2008 Issue Published: 1 September 1952 PDF downloadLoading ...