Pernicious Anemia: The Behavior of Various Extracts of Stomach and Duodenum Used to Induce Remissions
Authors: Elwood A. Sharp, Richard M. Mckean, Elmore C. Vonder Heide
Journal: Annals of Internal Medicine (1931)

Article1 April 1931Pernicious Anemia: The Behavior of Various Extracts of Stomach and Duodenum Used to Induce RemissionsELWOOD A. SHARP, M.D., RICHARD M. MCKEAN, M.D., ELMORE C. VONDER HEIDE, M.D.ELWOOD A. SHARP, M.D.Search for more papers by this author, RICHARD M. MCKEAN, M.D.Search for more papers by this author, ELMORE C. VONDER HEIDE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-4-10-1282 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn September, 1929, one of us (E. A. S.)1 reported the presence of an antianemic factor in desiccated hog stomach. The clinical evaluation of these stomach preparations in pernicious anemia was described by Sturgis and Isaacs2, and later by Renshaw3. Subsequently, the value of stomach tissue in this disease was confirmed by Connor4, Wilkinson5, Geuting6, Godel7, Jagic and Klima8 and others, working independently.Since the ratio of dried gastric tissue to raw substance is low, thereby entailing the daily use of 20 to 40 gm. of desiccated substance to induce a remission in pernicious anemia during a severe relapse, efforts...Bibliography1 SHARP EA An Antianemic Factor in Desiccated Stomach, J. A. M. A., 93:749 (Sept. 7) 1929. CrossrefGoogle Scholar2 STURGISISAACS CCR: Desiccated Stomach in the Treatment of Pernicious Anemia, J. A. M. A., 93:747-749 (Sept. 7) 1929. CrossrefGoogle Scholar3 RENSHAW A: The Treatment of Pernicious Anemia with Desiccated Hog's Stomach, Brit. M. J., 1:334-335, (Feb. 22) 1930. CrossrefMedlineGoogle Scholar4 CONNOR HM: The Treatment of Pernicious Anemia with Swine Stomach, J. A. M. A., 93:338-390 (Feb. 8) 1930. Google Scholar5 WILKINSON JF: Pernicious Anemia, Brit. M. J., 1:236-239, (Feb. 8) 1930. CrossrefMedlineGoogle Scholar6 GEUTING H: Die Behandlung der Perniziösen Anämie mit einem Magensubstanz-Organpräparat, Deutsche med. Wchnschr., 56:1219-1220, (July 18) 1930. Google Scholar7 GODEL R: Behandlung der Perniziösen Anämie mit Ventraemon (Magenpräparat). Wien. klin. Wchnschr., 43:812-814 (June 26) 1930. Google Scholar8 JAGICKLIMA NR: Zur Therapie der Perniziösen Anämie mit Ventraemon. Wien. klin. Wchnschr., 43:877-878 (July 10) 1930. Google Scholar9 ISAACSSTURGIS RCC: Some Newer Remedies in the Treatment of Pernicious Anemia: Desiccated Stomach. J. A. M. A., 95:585-587 (Aug. 23) 1930. CrossrefGoogle Scholar10 RIDDLE MC: Pernicious Anemia: Blood Regeneration During Early Remission, Arch. Int. Med., 46:417-439 (Sept.) 1930. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Detroit, Michigan*From the Metabolism Section, Receiving Hospital, Detroit, Mich.†Material furnished by Parke, Davis & Company. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byVitamin B12 in the Blood and in the Liver of Normal and of Totally Gastrectomized PigsIntestinal Synthesis of Vitamins in the NonruminantHematopoietic Activity (Intrinsic Factor Effect) of Pure Pyloric Secretion from the HogFurther Investigations into the Localisation of the Antianemic Factor (»Intrinsic Factor») in the StomachDie Krankheiten des MagensExperimental Studies on Production of Pernicious Anemia by Operation on the Digestive Tract1Experimental studies on production of pernicious anemia by operation on the digestive tract1On the Antianemic Function of the Small Intestine1Blutkrankheiten und NervensystemOn the Presence of Antianemic Activity in the IIeal Part of the Small Intestine1EXPERIMENTELLE UNTERSUCHUNGEN ÜBER GASTROGENE ANÄMIEN (BEI HUNDEN)The relation of gastrectomy to anemiaThe Presence of the Antianaemic Factor in Preparations of Dried Stomach Substance from the Cardia, Fundus and Pylorus Respectively1.Physiologie und Pathologie des Antiperniciosaprinzips 1 April 1931Volume 4, Issue 10Page: 1282-1286KeywordsBehaviorDuodenumPernicious anemiaStomach Issue Published: 1 April 1931 PDF downloadLoading ...