COCCIDIOIDAL MENINGITIS: REPORT OF FOUR CASES WITH NECROPSY FINDINGS IN THREE CASES
Authors: V E JENKINS, J C POSTLEWAITE
Journal: Annals of Internal Medicine (1951)

Article1 November 1951COCCIDIOIDAL MENINGITIS: REPORT OF FOUR CASES WITH NECROPSY FINDINGS IN THREE CASESV. E. JENKINS, M.D., J. C. POSTLEWAITE, M.D.V. E. JENKINS, M.D.Search for more papers by this author, J. C. POSTLEWAITE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-35-5-1068 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSince Wernicke's original description in 1892 of the disease coccidioidomycosis,1a, 1b knowledge of its natural history has been greatly expanded. A complete review of this information is beyond the scope of this report; however, certain important facts may be summarized as follows:It was not until 1937 that Gifford and Dixon2, 3, 4 established the relationship of the benign disease known as "valley fever" or "desert rheumatism" to the serious infection known as coccidioidal granuloma. Both were caused by the organism Coccidioides immitis. The endemic areas of infection in the United States5 were well recognized prior to 1941.The signs...Bibliography1a. ForbusBestebreurtje WDAM: Coccidioidomycosis, a study of 95 cases of the disseminated type with special reference to the pathogenesis of the disease, Mil. Surgeon 99: 653-719, 1946. CrossrefMedlineGoogle Scholar1b. Wernicke R: Über einen Protozoenbefund bei Mycosis fungoides, Zentralbl. f. Bakt. 12: 859, 1892, cited by Forbus, W. D., and Bestebreurtje, A. M., ibid. Google Scholar2. Dickson EC: "Valley fever" of San Joaquin Valley and fungus coccidioides, California and West. Med. 47: 151-155, 1937. MedlineGoogle Scholar3. Dickson EC: Coccidioides infection, Arch. Int. Med. 59: 1027, 1937. CrossrefGoogle Scholar4. DicksonGifford ECMA: Coccidioidomycosis, primary type infection, Arch. Int. Med. 62: 853-871, 1938. CrossrefGoogle Scholar5. Smith CE: Coccidioidomycosis, M. Clin. North America 27: 790-807, 1943. CrossrefGoogle Scholar6. Lee RV: Coccidioidomycosis in Western Flying Training Command, California and West. Med. 61: 133-134, 1944. MedlineGoogle Scholar7. SweigertTurnerGillespie CFJWJB: Clinical and roentgenologic aspects of coccidioidomycosis, Am. J. M. Sc. 212: 652-673, 1946. CrossrefMedlineGoogle Scholar8. Dickson EC: Oidiomycosis in California with special reference to coccidioidal granuloma, including nine new cases of coccidioidal granuloma and one of systemic blastomycosis, Arch. Int. Med. 16: 1028-1044, 1915. CrossrefGoogle Scholar9. Taylor RG: Coccidioidal granuloma, Am. Roentgen. 10: 551, 1943. Google Scholar10. Whins CB: Coccidioidal meningitis, Bull. U. S. Army M. Dept. 7: 466-471, 1947. MedlineGoogle Scholar11. Coccidioidal granuloma in California in 1934-35, California and West Med. 46: 282, 1937. Google Scholar12. Courville CB: Primary chronic coccidioidal meningitis, Bull. Los Angeles Neur. Soc. 1: 116-119 (Sept.) 1936. Google Scholar13. SmithBeardSaito CERRMT: Pathogenesis of coccidioidomycosis with special reference to pulmonary cavitation, Ann. Int. Med. 29: 623-655, 1948. LinkGoogle Scholar14. GoldsteinLouie DMS: Primary pulmonary coccidioidomycosis, epidemic of 75 cases, War Med. 4: 299-317, 1943. Google Scholar15. Ophuls W: Further observations on a pathogenic mould formerly described as a protozoon (Coccidioides immitis, Coccidioides pyogenes), J. Exper. Med. 6: 443, 1905. CrossrefMedlineGoogle Scholar16. AbbottCutler KHOI: Chronic coccidioidal meningitis: review of literature and report of 7 cases, Arch. Path. 21: 320-330, 1936. Google Scholar17. Jacobson HP: Granuloma coccidioides apparently successfully treated with colloidal copper: 2 cases, California and West Med. 27: 360-364, 1927. MedlineGoogle Scholar18. da Costa AF: Treatment of coccidioidal granuloma by gold salts, case, Brasil-med. 43: 1400-1402, 1929. Google Scholar19. SorskyNixon EDCE: Coccidioidal granuloma with report of 18 cases with two apparent cures, California and West. Med. 42: 98-106, 1935. MedlineGoogle Scholar20. CheneyDenenholz GEJ: Diagnosis and treatment of chronic coccidioidomycosis, Arch. Int. Med. 74: 311-330, 1944. CrossrefGoogle Scholar21. CumminsSmithHolliday WTJRCH: Coccidioidal granuloma: epidemiological survey with report of 24 cases, J. A. M. A. 41: 145-148, 1929. Google Scholar22. PulfordLarson DSEE: Coccidioidal granuloma; a case treated by intravenous dye, colloidal lead and colloidal copper with autopsy observations, J. A. M. A. 93: 1049-1055, 1929. CrossrefGoogle Scholar23. Hektoen L: Systemic blastomycosis and coccidioidal granuloma, J. A. M. A. 49: 1071-1077, 1907. CrossrefGoogle Scholar24. ClipmenTempleton EDHJ: Coccidioidal granuloma, Arch. Dermat. and Syph. 21: 259-278, 1930. CrossrefGoogle Scholar25. Tomlinson CC: Coccidioides granuloma, M. Clin. North America 12: 188-189, 1928. Google Scholar26. GoldsteinMcDonald DMJB: Primary coccidioidomycosis, pulmonary, J. A. M. A. 124: 557-561, 1944. CrossrefGoogle Scholar27. CraigDockerty WMMB: Coccidioidal granuloma; brief review with report of case of meningeal involvement, Minnesota Med. 24: 150-154, 1941. Google Scholar28. Haynes NA: Progressive coccidioidomycosis, Ann. Int. Med. 28: 651-662, 1948. LinkGoogle Scholar29. RosenbergDockertyMeyerding EFMBHW: Coccidioidal arthritis; report of case with ankle involvement and no results with sulfanilamide and roentgen therapy, Arch. Int. Med. 69: 238-250, 1942. CrossrefGoogle Scholar30. Harvey NA: Progressive coccidioidomycosis, Ann. Int. Med. 28: 651-661, 1948. LinkGoogle Scholar31. McCracken JP: Coccidioidomycosis, North Carolina M. J. 6: 25-31, 1945. Google Scholar32. MichaelMcLaughlinCenac PRFPL: Unsuccessful treatment of coccidioidomycosis with penicillin, U. S. Naval M. Bull. 43: 122-124, 1944. Google Scholar33. Schlumberger HG: A fatal case of cerebral coccidioidomycosis with cultural studies, Am. J. M. Sc. 209: 483, 1945. CrossrefGoogle Scholar34. QuickBradfieldMitz DWJYR: Coccidioidomycosis: report of a case with unusual complications, Texas State J. Med. 45: 706-709 (Oct.) 1949. MedlineGoogle Scholar35. Personal communications, The Upjohn Company, Kalamazoo, Mich., A supplementary Summary Report for the Midwest Group, Dec. 16, 1947. Google Scholar36. Personal communications, The Upjohn Company, Kalamazoo, Michigan, Acti-Dione, 1949. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication September 11, 1950.From the Department of Medicine, Veterans Administration Hospital, McKinney, Texas, and Southwestern Medical School of the University of Texas, Dallas, Texas.Reviewed in the Veterans Administration and published with the approval of the Chief Medical Director. The statements and conclusions published by the authors are the result of their own study and do not necessarily reflect the opinion or policy of the Veterans Administration. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byCentral nervous system coccidioidomycosis: A clinicopathologic study of treatment with and without amphotericin BCoccidioidal MeningitisCoccidioidomycosis of the Larynx in Infants and AdultsRaumbeengende Prozesse im Spinalkanal (einschließlich Angiome und Parasiten)CoccidioidomycosisCoccidioidomycosisCoccidioidal Meningitis — Roentgen and Pathologic AnalysesAcute cerebral phycomycosis (mucormycosis)Mycology 1 November 1951Volume 35, Issue 5Page: 1068-1084KeywordsCoccidioidesCoccidioidomycosisFeversGranulomasHospital medicineInfectious diseasesMeningitisNatural history of disease ePublished: 1 December 2008 Issue Published: 1 November 1951 PDF downloadLoading ...