Nitroglycerin as a Remedy for Peripheral Vascular Insufficiency Associated with Oxalosis
Authors: ALLEN J. DENNIS
Journal: Annals of Internal Medicine (1980)

Brief Reports1 June 1980Nitroglycerin as a Remedy for Peripheral Vascular Insufficiency Associated with OxalosisALLEN J. DENNIS Jr., M.D., JAMES B. HUDSON, M.D., ARTHUR L. HUMPHRIES, M.D., GAUTAM DASGUPTA, M.B.B.S., CHARLES H. WRAY, M.D.ALLEN J. DENNIS Jr., M.D.Search for more papers by this author, JAMES B. HUDSON, M.D.Search for more papers by this author, ARTHUR L. HUMPHRIES, M.D.Search for more papers by this author, GAUTAM DASGUPTA, M.B.B.S.Search for more papers by this author, CHARLES H. WRAY, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-92-6-799 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSevere peripheral vascular insufficiency is a rare complication of oxalosis (primary hyperoxaluria) (1), but when it is present its effects can be devastating (2-4). Although it may be self-limited (5), no successful therapy has been reported.A 32-year-old housewife was admitted to the Eugene Talmadge Memorial Hospital because of uremia secondary to oxalosis.The patient's brother had died 16 years previously with uremia due to oxalosis. She was found to have an elevated urinary oxalate excretion of 101 mg/24 h (normal range 15 to 49 mg/24 h). Her parents were cousins.She passed her first kidney stone at the age...References1. WILLIAMS H and SMITH L. Primary hyperoxaluria. In: STANBURY JB, WYNGAARDEN, JB, FREDRICKSON DS, eds. The Metabolic Basis of Inherited Disease. 4th ed., New York: McGraw-Hill Book Co.; 1978:182-204. Google Scholar2. BOQUIST L, LINDQVIST B, ÖSTBERG Y, and STEEN L. Primary oxalosis. Am J Med. 1973;54:673-81. CrossrefMedlineGoogle Scholar3. ARBUS G and SNIDERMAN S. Oxalosis with peripheral gangrene. Arch Pathol. 1974;97:107-10. MedlineGoogle Scholar4. BLACKBURN W, MCROBERTS J, BHATHENA D, VAZQUEZ M, and LUKE R. Severe vascular complications in oxalosis after bilateral nephrectomy. Ann Intern Med. 1975; 82:44-6. LinkGoogle Scholar5. MATHEWS M, STAUFFER M, CAMERON E, MALONEY N, and SHERRARD D. Bone biopsy to diagnose hyperoxaluria in patients with renal failure. Ann Intern Med. 1979;90:777-9. LinkGoogle Scholar6. MOHR W and HEY D. Endogene Oxalose mit Manifestation im Erwachsenenalter. Virchows Arch [Pathol Anat]. 1969;347:185-96. CrossrefMedlineGoogle Scholar7. KLAUWERS J, WOLF P, and COHN R. Failure of renal transplantation in primary oxalosis. JAMA. 1969;209:551. CrossrefMedlineGoogle Scholar8. KOTEN J, VAN GASTEL C, DORHOUT MEES E, HOLLEMAN L, and SCHUILING R. Two cases of primary oxalosis. J Clin Pathol. 1965;18:223-9. CrossrefMedlineGoogle Scholar9. LUND F. Percutaneous nitroglycerin treatment in cases of peripheral circulatory disorders, especially Raynaud's disease. Acta Med Scand. 1948;206:(suppl) 196-206. Google Scholar10. GOLDSTEIN R, STINSON E, SCHERER J, SENINGEN R, GREHL T, and EPSTEIN S. Intraoperative coronary collateral function in patients with coronary occlusive disease: nitroglycerin responsiveness and angiographic correlations. Circulation. 1974;49:298-308. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: ALLEN J. DENNISJr., M.D.; JAMES B. HUDSON, M.D.; ARTHUR L. HUMPHRIES, M.D.; GAUTAM DASGUPTA, M.B.B.S.; CHARLES H. WRAY, M.D.Affiliations: The Departments of Medicine and Surgery Medical College of Georgia Augusta, Georgia PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byVascular Occlusion and Cardiac Conduction Disturbances in a Patient Undergoing Peritoneal DialysisLivedo reticularis and peripheral gangrene associated with primary hyperoxaluria 1 June 1980Volume 92, Issue 6Page: 799-800KeywordsExcretionKidney stonesVascular insufficiency ePublished: 1 December 2008 Issue Published: 1 June 1980 PDF downloadLoading ...