Serum Proteins in Infectious Mononucleosis
Authors: KENNETH D. ROSE
Journal: Annals of Internal Medicine (1966)

Article1 April 1966Serum Proteins in Infectious MononucleosisKENNETH D. ROSE, M.D.KENNETH D. ROSE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-64-4-826 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlthough much has been written concerning the various histological, biochemical, and serological manifestations of infectious mononucleosis (1), there is very little published on the serum protein variations associated with this disease. Sterling (2) studied seven cases by microcell electrophoresis, reporting a diminution of serum albumin (60.3 to 49.9%) and an elevation of the gamma globulins (13.2 to 19.0%). Less pronounced and less frequent were alpha-1 and beta globulin elevations. Hepatic involvement is common, essentially universal, in infectious mononucleosis (1, 3-5). Sterling (2), observing this in six of his seven patients, suggested that the dysproteinemia might be associated with disturbed hepatocellular...References1. DAVIDSOHNLEE ICL: The laboratory in the diagnosis of infectious mononucleosis, with additional notes on epidemiology, etiology and pathogenesis. Med. Clin. N. Amer. 46: 225, 1962. CrossrefMedlineGoogle Scholar2. STERLING K: The serum proteins in infectious mononucleosis. Electrophoretic studies. J. Clin. Invest. 28: 1057, 1949. CrossrefMedlineGoogle Scholar3. BARONDESSERLE JSH: Serum alkaline phosphatase activity in hepatitis of infectious mononucleosis. Amer. J. Med. 29: 43, 1960. CrossrefMedlineGoogle Scholar4. ROBERTGROSSI LCE: The behavior of the transaminase activity of the serum in infectious mononucleosis. Arch. Maragliano Pat. Clin. 18: 267, 1962; Biol. Abs. 42: 17227, 1963. MedlineGoogle Scholar5. GELBWESTZIMMERMAN DMHJ: Serum enzymes in disease. IX. 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Rose, M.D., University of Nebraska Health Service, 15th and U St., Lincoln, Neb. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDie infektiöse MononucleoseCold Agglutinins of Anti-i Specificity in Alcoholic Cirrhosis 1 April 1966Volume 64, Issue 4Page: 826-833KeywordsGlobulinsHyperglobulinemiaInfectious diseasesProteinsResearch laboratoriesSerum albuminSerum proteinsSteroid therapy ePublished: 1 December 2008 Issue Published: 1 April 1966 PDF downloadLoading ...