The Physician's Incompleat Guide to Atherosclerosis
Authors: IRVINE H. PAGE
Journal: Annals of Internal Medicine (1966)

Review1 January 1966The Physician's Incompleat Guide to AtherosclerosisIRVINE H. PAGE, M.D., F.A.C.P., JEROME G. GREEN, M.D., ABEL LAZZARINI ROBERTSON, M.D., PH.D.IRVINE H. PAGE, M.D., F.A.C.P.Search for more papers by this author, JEROME G. GREEN, M.D.Search for more papers by this author, ABEL LAZZARINI ROBERTSON, M.D., PH.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-64-1-189 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIt has only been some 30 years that interest in the mechanisms of atheropoiesis, or atherogenesis, has been sufficient to create almost utter confusion! Conflicting evidence and opinions are presented almost daily in the public and scientific presses. By now, the public has come to believe that neither the scientist nor the physician has any true idea of what he is talking about!But why does this make so much difference to people? Chiefly because two major aspects of life are involved. The one concerns what we eat and drink and the other our chances of early death from heart...References*1. PAGE IH: The Lewis A. Connor Memorial Lecture. Atherosclerosis. An introduction. Circulation 10: 1, 1954. CrossrefMedlineGoogle Scholar2. ROBERTSON AL: The uptake of labelled lipoproteins by isolated human and animal endothelial type cells, in The Mode of Action of Drugs, Vol. 2. Pergamon Press, Oxford, 1963, pp. 193-209. Google Scholar3. DEAN G: The Porphyrias. Pitman Medical Publishing Company, London, 1963. Google Scholar4. MUSTARDMURPHYROWSELLDOWNIE JFEAHCHG: Factors influencing thrombus formation in vivo. Amer. J. Med. 33: 621, 1961. CrossrefGoogle Scholar5. 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KEYSANDERSONGRANDE AJTF: Serum cholesterol in man: diet fat and intrinsic responsiveness. Circulation 19: 201, 1959. CrossrefMedlineGoogle Scholar20. WILKENSDEWITBRONTE-STEWART JAHB: A proposed mechanism for the effect of different dietary fats on some aspects of cholesterol metabolism. Canad. J. Biochem. Physiol. 40: 1091, 1962. CrossrefMedlineGoogle Scholar21. YUDKINRODDY JJ: Levels of dietary sucrose in patients with occlusive atherosclerotic disease. Lancet 2: 6, 1964. CrossrefMedlineGoogle Scholar22. MACDONALDBRAITHWAITE IDM: The influence of dietary carbohydrates on the lipid in serum and in adipose tissue. Clin. Sci. 27: 23, 1964. MedlineGoogle Scholar23. CONNORSTONEHODGES WEDBRE: The interrelated effects of dietary cholesterol and fat upon human serum lipids. J. Clin. Invest. 43: 1691, 1964. CrossrefMedlineGoogle Scholar24. DINMAN BB: Calories, polyunsaturates, and confusion. Arch. Environ Health (Chicago) 9: 693, 1964. CrossrefGoogle Scholar25. HORWITT MK: Interrelations between vitamin E and polyunsaturated fatty acids in adult men, in Vitamins and Hormones, edited by HARRIS, R. S., WOOL, I. G. Vol. 20, Academic Press, New York, 1962, pp. 541-557. Google Scholar26. HARRISHARDENBROOKDEANCUSACKJENSEN PLEGFPERJL: Blood tocopherol values in normal human adults and incidence of vitamin E deficiency. Proc. Soc. Exp. Biol. Med. 107: 381, 1961. CrossrefMedlineGoogle Scholar27. HARRISEMBREE PLND: Quantitative consideration of the effect of polyunsaturated fatty acid content of the diet upon the requirements for vitamin E. Amer. J. Clin. Nutr. 13: 385, 1963. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Cleveland, OhioFrom the Research Division of the Cleveland Clinic Foundation, Cleveland, Ohio.This study was supported in part by grants H-6835 and H-8253 from the Public Health Service, Bethesda, Md., and grant 62-G-108 from the American Heart Association.Requests for reprints should be addressed to Irvine H. Page, M.D., Research Divisions, Cleveland Clinic, 2020 E. 93 St., Cleveland, Ohio 44106. 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HAMWI, M.D., F.A.C.P.Study of the movement in vivo and in vitro of labelled cholesterol across the aorta of the normal ratPrimary prevention of coronary heart disease by dietThe Present State of Knowledge About the Prevention and Therapy of Atherosclerosis 1 January 1966Volume 64, Issue 1Page: 189-203KeywordsAtherosclerosisHeartLongitudinal studiesMedical servicesScientists Issue Published: 1 January 1966 PDF downloadLoading ...