PRESENT INDICATIONS FOR CORTISONE THERAPY IN ACUTE VIRAL HEPATITIS
Authors: R S NELSON
Journal: Annals of Internal Medicine (1957)

Article1 April 1957PRESENT INDICATIONS FOR CORTISONE THERAPY IN ACUTE VIRAL HEPATITISROBERT S. NELSON, M.D., F.A.C.P.ROBERT S. NELSON, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-46-4-685 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe effects of ACTH and cortisone administration on patients with acute viral hepatitis are now well substantiated.1, 2, 4, 5Foremost among these are the more rapid return of the serum bilirubin to normal and a marked increase in appetite. In a controlled series where patients were graded as to severity before being admitted to the study, cortisone administration resulted in a return of bromsulphalein retention, histologic abnormalities and signs and symptoms of the disease to normal more rapidly than in controls. Our experiences with ACTH led us to believe that this hormone was less desirable than cortisone, perhaps because...Bibliography1. DucciKatz HR: Cortisone, ACTH and antibiotics in fulminant hepatitis, Gastroenterology 21: 357-374, 1952. CrossrefMedlineGoogle Scholar2. EvansSprinzNelson ASHRS: Adrenal hormone therapy in viral hepatitis. II. The effect of cortisone in the acute disease, Ann. Int. Med. 38: 1134, 1953. LinkGoogle Scholar3. EvansSprinzNelson ASHRS: Adrenal hormone therapy in viral hepatitis. III. The effect of ACTH and cortisone in severe and fulminant cases, Ann. Int. Med. 38: 148, 1953. Google Scholar4. EvansNelsonSprinzCantrell ASRSHFP: Adrenal hormone therapy in viral hepatitis. IV. The effect of gamma globulin and oral cortisone in the acute disease, Am. J. Med. 19: 783-789, 1955. CrossrefMedlineGoogle Scholar5. HubertWiley TEAT: Cortisone in the treatment of infectious hepatitis, Ann. Int. Med. 42: 1011, 1955. LinkGoogle Scholar6. Nelson RS: Treatment in severely ill and comatose viral hepatitis patients, M. Bull. U. S. Army, Europe 10: 175, 1953. MedlineGoogle Scholar7. Nelson RS: The development and function of a liver biopsy program: training of personnel, description of a modified Vim-Silverman needle and clinical value of 500 biopsies, Am. J. M. Sc. 227: 152, 1954. CrossrefMedlineGoogle Scholar8. SwiftGardnerMooreStreitfeldHavens WEHTDJFHWP: Clinical course of viral hepatitis and the effect of exercise during convalescence, Am. J. Med. 8: 614, 1950. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Houston, Texas*Received for publication June 11, 1956.From the Gastroenterology Service, Brooke Army Hospital, Brooke Army Medical Center, San Antonio, Texas.Requests for reprints should be addressed to Robert S. Nelson, M.D., M. D. Anderson Hospital6723 Bertner, Houston 25, Texas. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAktuelle Probleme der Pathogenese und Therapie verschiedener Schockformen in der inneren Medizin (Symposion)A fortuitously controlled study of steroid therapy in acute viral hepatitisAcute Hepatic Coma Treated by Cross-Circulation or Exchange TransfusionCorticotropin and Corticosteroids in Human Viral InfectionsSteroids in InfectionThe Management of Severe Viral HepatitisThe Hepatic Metabolism of Adrenocortical Steroids and Some Clinical Implications ThereofSerum enzymes (transaminases, phosphoglucomutase, fumarase) in viral hepatitis during prednisone (δ1-cortisone) therapyJaundice associated with the administration of iproniazidMUMPS MYOCARDITIS: CASE REPORT WITH REVIEW OF THE LITERATURE*GLENN E. HORTON, M.D.CHICKENPOX PNEUMONIA TREATED WITH PREDNISOLONE: A CASE REPORT*C. A. THOMPSON, M.D., F. P. CANTRELL, M.D.Parenchymatous Liver Disease (1956-1957)The proper use of adrenal hormonal drugs in pediatric practiceThe Use of ACTH and Adrenocorticosteroids in Diseases of the Digestive SystemACTH and Adrenocorticosteroids as Therapeutic Adjuncts in Infectious Diseases 1 April 1957Volume 46, Issue 4Page: 685-695KeywordsAdrenocorticotropic hormoneBilirubinComaHepatitisHepatitis AHepatitis EHormonesNauseaNecrosisSigns and symptoms ePublished: 1 December 2008 Issue Published: 1 April 1957 PDF downloadLoading ...