THE HEREDITY OF GOUT AND ITS RELATIONSHIP TO FAMILIAL HYPERURICEMIA
Authors: R M STECHER, A H HERSH, W M SOLOMON
Journal: Annals of Internal Medicine (1949)

Article1 October 1949THE HEREDITY OF GOUT AND ITS RELATIONSHIP TO FAMILIAL HYPERURICEMIAROBERT M. STECHER, M.D., F.A.C.P., A. H. HERSH, Ph.D., WALTER M. SOLOMON, M.D., F.A.C.P.ROBERT M. STECHER, M.D., F.A.C.P.Search for more papers by this author, A. H. HERSH, Ph.D.Search for more papers by this author, WALTER M. SOLOMON, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-31-4-595 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptDespite the fact that gout has long been recognized as a hereditary disease and that much study has been devoted to this phase of the problem, the exact pattern of inheritance has not been clearly identified. It seemed likely that a broader concept of the disease and the application of modern methods of genetic investigation to readily available data might add much to our understanding of the disease. The present study was undertaken in the hope that these potentialities might be realized.The most striking features of gout have always been associated with the joint phenomena. Characteristically these consist of...Bibliography1. MCCRACKENOWENPRATT JPPSJH: Gout: still a forgotten disease, Jr. Am. Med. Assoc., 1946, cxxxi, 367-372. CrossrefGoogle Scholar2. BROCHNER-MORTENSEN K: One hundred gouty patients, Acta med. Scandinav., 1941, cvi, 81-107. Google Scholar3. FOLINDAVIS OW: The diagnostic value of uric acid determinations in blood, Arch. Int. Med., 1915, xvi, 33-37. CrossrefGoogle Scholar4. JACOBSON DM: Uric acid in serum of gouty and non-gouty individuals; its determination by Folin's recent method and its significance in the diagnosis of gout, Ann. Int. Med., 1938, xi, 1277-1295. LinkGoogle Scholar5. TALBOTT JH: Serum urate in relatives of gouty patients, Jr. Clin. Invest., 1940, xix, 645-648. CrossrefGoogle Scholar6. 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GUTMAN, M.D., F.A.C.P.RHEUMATISM AND ARTHRITIS REVIEW OF AMERICAN AND ENGLISH LITERATURE OF RECENT YEARS (TENTH RHEUMATISM REVIEW)* Part IIWILLIAM D. ROBINSON, M.D., F.A.C.P., EDWARD W. BOLAND, M.D., F.A.C.P., JOSEPH J. BUNIM, M.D., F.A.C.P., DARRELL C. CRAIN, M.D., F.A.C.P., EPHRAIM P. ENGLEMAN, M.D., F.A.C.P., WALLACE GRAHAM, M.D., F.R.C.P. (C), L. MAXWELL LOCKIE, M.D., F.A.C.P., MAX M. MONTGOMERY, M.D., F.A.C.P., CHARLES RAGAN, M.D., F.A.C.P., MARIAN W. ROPES, M.D., F.A.C.P., EDWARD F. ROSENBERG, M.D., F.A.C.P., CHARLEY J. SMYTH, M.D.Current principles of management in goutNote on the Genetics of Hypercholesterolemia 1 October 1949Volume 31, Issue 4Page: 595-614KeywordsAdrenocorticotropic hormoneArthritisBlood plasmaGenetic determinismGenetic diseasesGeneticsGoutHeredityHospital medicineUric acid Issue Published: 1 October 1949 PDF downloadLoading ...