THE ASSOCIATION OF MILIARY TUBERCULOSIS OF THE BONE MARROW AND PANCYTOPENIA
Authors: T S EVANS, V A DE LUCA, L L WATERS
Journal: Annals of Internal Medicine (1952)

Case Reports1 November 1952THE ASSOCIATION OF MILIARY TUBERCULOSIS OF THE BONE MARROW AND PANCYTOPENIATHEODORE S. EVANS, M.D., F.A.C.P., VINCENT A. DELUCA JR., LEVIN L. WATERS, M.D.THEODORE S. EVANS, M.D., F.A.C.P.Search for more papers by this author, VINCENT A. DELUCA JR.Search for more papers by this author, LEVIN L. WATERS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-37-5-1044 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptA patient with pancytopenia recently came to necropsy in this hospital. A totally unsuspected disseminated tuberculous process was found in the viscera and bone marrow. It has been thought of interest to call attention to the alterations of the peripheral blood and bone marrow associated with miliary or disseminated tuberculosis, and to describe the findings in the present case.LITERATUREAlterations in the peripheral blood in tuberculosis were recognized in the earliest days of blood counting. Apparently the first report associating such changes with tuberculosis of the bone marrow is that of Donhauser1in 1908. In his patient, the bone...Bibliography1. Donhauser JL: Human spleen as a hematopoietic organ as exemplified in a case of splenomegaly with sclerosis of bone marrow, J. Exper. Med. 10: 559, 1908. CrossrefMedlineGoogle Scholar2. Wiechmann E: Miliary tuberculosis and secondary myeloblastosis, Med. Klin. 18: 1086, 1922. Google Scholar3. Dyke SC: Some cases of aleukemia or aplastic anemia associated with thrombopenia, Lancet 1: 1048, 1924. CrossrefGoogle Scholar4. DoanSabin CAF: Local progression with spontaneous regression of tuberculosis in bone marrow of rabbits, correlated with a transitory anemia and leucopenia, after intravenous inoculation, J. Exper. Med. 46: 315-341, 1927. CrossrefMedlineGoogle Scholar5. DoanMoore CD: Two cases of tuberculosis, Am. Rev. Tuberc. 2: 409, 1931. Google Scholar6. CusterCrocker RPWJ: The myeloleukaemoid blood picture associated with tuberculosis, Folia haemat. 46: 359, 1932. Google Scholar7. KriechHeni HF: The simultaneous occurrence of acute miliary tuberculosis and panmyelophthisis, Klin. Wchnschr. 14: 781, 1935. CrossrefGoogle Scholar8. Fortunato A: Leukemia and tuberculosis, clinical observations, Gazz. d. Osp. 59: 834, 1938. Google Scholar9. UlrichParks HH: Relation between leukemia and tuberculosis, New England J. Med. 222: 711, 1940. CrossrefGoogle Scholar10. Schleicher EM: Miliary tuberculosis of the bone marrow, Am. Rev. Tuberc. 53: 115, 1946. MedlineGoogle Scholar11. ChapmanWhorton CC: Acute generalized miliary tuberculosis in adults, New England J. Med. 235: 239, 1946. CrossrefMedlineGoogle Scholar12. GardnerMettier FHSR: Lymphocytic leukemoid reaction of the blood associated with miliary tuberculosis, Blood 4: 767, 1949. CrossrefMedlineGoogle Scholar13. StaffurthSpencer JSH: Aleukemic leukemoid response in miliary tuberculosis, Blood 5: 1161, 1950. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New Haven, Connecticut*Received for publication September 15, 1951.From the Departments of Medicine and Pathology of the Grace Unit, Grace-New Haven Community Hospital, New Haven, Connecticut. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byMycobacterial disease associated with aplastic anaemiaMYCOBACTERIAL INFECTIONS AND LEUCOPENIAACTIVE TUBERCULOSIS UNRECOGNISED UNTIL NECROPSYDie Panmyelopathie und andere Formen der PancytopenieAplastic anemia in Shiraz, an analysis of 50 cases with special reference to etiological agents in Southwest IranCase 12-1963Case 43281Acute tuberculous septicaemia 1 November 1952Volume 37, Issue 5Page: 1044-1052KeywordsBloodBoneBone marrowHospital medicineMiliary tuberculosis ePublished: 1 December 2008 Issue Published: 1 November 1952 PDF downloadLoading ...