OBSERVATIONS ON A CASE OF ERYTHREMIC MYELOSIS
Authors: J. Metz, H. R. Klein
Journal: Annals of Internal Medicine (1960)

Case Reports1 July 1960OBSERVATIONS ON A CASE OF ERYTHREMIC MYELOSISJ. METZ, M.D., B.Ch., H. R. KLEIN, M.B., B.Ch., M.R.C.P., M.R.C.P.E.J. METZ, M.D., B.Ch.Search for more papers by this author, H. R. KLEIN, M.B., B.Ch., M.R.C.P., M.R.C.P.E.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-53-1-207 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptWhile the nature of erythremic myelosis (di Guglielmo's disease) remains controversial, it is not surprising that the diagnosis may give rise to considerable difficulty. The differentiation from various forms of hemolytic anemia and from severe cases of pernicious anemia presents well recognized difficulties. The application of diagnostic aids of more recent development has been limited by the rarity of the disease; this limitation would seem to warrant the presentation of a case of erythremic myelosis where the red cell survival and serum vitamin B12content were estimated, and a cytochemical abnormality in the marrow normoblasts, of possible diagnostic value, was...Bibliography1. AstaldiRondenelliBernardelliStrosselli GEGEE: An abnormal substance present in the erythroblasts of thalassaemia major: cytochemical investigations, Acta haemat. 12: 145-153, 1954. CrossrefMedlineGoogle Scholar2. Dornhorst AC: Interpretation of red cell survival curves, Blood 6: 1284-1292, 1951. CrossrefMedlineGoogle Scholar3. GreigMetz HBJ: The periodic-acid-Schiff reaction as a diagnostic aid in thalassaemia, South African J. M. Sc. 22: 7-12, 1957. MedlineGoogle Scholar4. di Guglielmo G: Les maladies érythrémiques, Rev. d'hémat. 1: 355-398, 1946. Google Scholar5. SchwartzCritchlow SOJ: Erythremic myelosis (di Guglielmo's disease). Critical review with report of four cases, and comments on erythroleukemia, Blood 7: 765-793, 1954. CrossrefGoogle Scholar6. Stodtmeister R: Akute Erythroblastose und erythroblastische Reaktion, Klin. Wchnschr. 20: 444-448, 1941. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Johannesburg,*Received for publication January 6, 1959.From the South African Institute for Medical Research and the Department of Medicine of Baragwanath Hospital, Johannesburg, South Africa.Requests for reprints should be addressed to The Librarian, South African Institute for Medical Research, P.O. Box 1038, Johannesburg,South Africa. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byA bibliography of the leukaemias in Africa, 1904–1985Schistocytes in ErythroleukemiaA new observation in the clinical spectrums of erythroleukemiaEntwicklung von Di Guglielmo-Syndromen aus chronischen myeloischen LeukämienLEUKÆMIA AND ALLIED DISORDERS 1. CONCEPTS, DEFINITIONS AND CLASSIFICATIONSAkute und chronische Erythrämie (Erythromyelose)Coexistence of pernicious anaemia and acute erythraemic myelosis 1 July 1960Volume 53, Issue 1Page: 207-215KeywordsAnemiaBeta-thalassemiaBone marrowBone marrow cellsFolic acidHemoglobinHemolytic anemiaHemorrhageHospital medicinePernicious anemia ePublished: 1 December 2008 Issue Published: 1 July 1960 PDF downloadLoading ...