Acid Hyperphenylphosphatasia in Thrombophlebitis and Pulmonary Embolism
Authors: MYRON R. SCHOENFELD
Journal: Annals of Internal Medicine (1962)

Brief Communication1 September 1962Acid Hyperphenylphosphatasia in Thrombophlebitis and Pulmonary EmbolismMYRON R. SCHOENFELD, M.D., HAROLD LEPOW, M.D., FANYA WOLL, GLORIA EDISMYRON R. SCHOENFELD, M.D.Search for more papers by this author, HAROLD LEPOW, M.D.Search for more papers by this author, FANYA WOLLSearch for more papers by this author, GLORIA EDISSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-57-3-468 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptErythrocytes and platelets are rich in acid phosphatase (1-4). Therefore, it occurred to us that perhaps the destruction of blood cells enmeshed within the blood clots of patients with thrombo-embolic diseases would release into the serum sufficient quantities of the enzyme to be of diagnostic value. We chose to measure acid phenylphosphatase activity, mainly because we had had extensive experience with the required chemical techniques. The results of our preliminary observations on patients with thrombophlebitis or pulmonary embolism are presented below. Studies on cases of coronary thrombosis, cerebral thrombosis, and systemic embolization are in progress and will be reported at...References1. MARTLANDHAUSMANROBINSON MFSR: Phosphoric esterase of blood. Biochem. J. 18: 1152, 1924. CrossrefMedlineGoogle Scholar2. ROCHE J: Blood phosphatases. Biochem. J. 25: 1724, 1931. CrossrefMedlineGoogle Scholar3. ZUCKERBORRELLI MBJA: A survey of some platelet enzymes and function. The platelets as the source of normal serum acid glycerophosphatase. Ann. N. Y. Acad. Sci. 75: 203, 1958. CrossrefMedlineGoogle Scholar4. ZUCKERBORRELLI MBJA: Platelets as a source of serum acid nitro-phenyl-phosphatase. J. Clin. Invest. 38: 148, 1959. CrossrefMedlineGoogle Scholar5. WHITMOREWOODARD WFHQ: The effects of prostatic surgery on the level of serum acid glycerophosphatase. J. Urol. 74: 809, 1955. CrossrefMedlineGoogle Scholar6. WOODARD HQ: The clinical significance of serum acid phosphatase. Amer. J. Med. 27: 902, 1959. CrossrefMedlineGoogle Scholar7. FISHMANBONNERHOMBURGER WHCDF: Serum "prostatic" acid phosphatase and cancer of the prostate. New Engl. J. Med. 225: 925, 1956. CrossrefGoogle Scholar8. GUTMANGUTMAN EBAB: Estimation of "acid" phosphatase activity of blood serum. J. Biol. Chem. 136: 201, 1940. CrossrefGoogle Scholar9. KINGARMSTRONG EJAR: A convenient method for determining serum and bile phosphatase activity. Canad. Med. Ass. J. 31: 376, 1934. MedlineGoogle Scholar10. GUTMAN AB: Serum "acid" phosphatase in patients with carcinoma of the prostate gland; present status. J. A. M. A. 120: 1112, 1942. CrossrefGoogle Scholar11. LEPOWSCHOENFELDMESSELOFFCHU HMRCRF: Non-prostatic causes of acid hyperphosphatasia. J. Urol. 87: 991, 1962. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, New YorkFrom the Medical Service and Department of Pathology, Lincoln Hospital, New York 54, New York.Requests for reprints should be addressed to Myron R. Schoenfeld, M.D., Medical Service, Lincoln Hospital, New York 54, New York. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByProstatic Acid Phosphatase: Its Current Clinical StatusAcid PhosphataseAcid phosphatase activity in carcinoma of the bronchusClinical significance of the human acid phosphatasesUsefulness of bone marrow serum acid phosphatase in staging carcinoma of the prostateACID PhosphataseBIBLIOGRAPHYPlasma acid phosphatase in normal and pre-eclamptic pregnancyPulmonary embolism and disseminated intravascular coagulationProteolytische Enzyme in normalen menschlichen BlutplättchenThe diagnostic value ofserum enzyme measurementsVergleichende untersuchungen von “sauren” plasmaphosphatasen bei verschiedenen knochenerkrankungenIncreased serum acid phosphatase after arterial embolismSerum Acid Phosphatase as An Index of Kidney DiseaseUse of the Plasma Acid Phosphatase Value in the Differentiation of Thrombocytopenic StatesAcid Phosphatase in Serum: Increase in Acute Myocardial Infarction 1 September 1962Volume 57, Issue 3Page: 468-471KeywordsAcid phosphataseBlood cellsEnzymesMedical servicesPhosphatasesPlateletsPulmonary embolismThrombosis Issue Published: 1 September 1962 PDF DownloadLoading ...