ONYCHOLYSIS IN HYPERTHYROIDISM
Authors: M N LURIA, S P ASPER
Journal: Annals of Internal Medicine (1958)

Article1 July 1958ONYCHOLYSIS IN HYPERTHYROIDISMMILTON N. LURIA, M.D., SAMUEL P. ASPER JR., M.D., F.A.C.P.MILTON N. LURIA, M.D., SAMUEL P. ASPER JR., M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-49-1-102 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptOf the many clinical features of Graves' disease, alterations in the nails are probably the least frequently recognized. The late Dr. Henry S. Plummer, of the Mayo Clinic, was apparently the first to call attention to trophic changes of the fingernails in hyperthyroidism. He described longitudinal striations and flattening of the nail which, when pronounced, produce a "scoop shovel" appearance. A more striking change in the nails, however, which Dr. Plummer also described and the one with which this communication is concerned, is the condition known as onycholysis. This clinical sign has been considered pathognomonic of Graves' disease for almost...Bibliography1. BoothbyPlummer WMWA: Diseases of the thyroid, in Christian's Oxford medicine, Chapter XV-A, 1937, Oxford University Press, New York. Google Scholar2. Means JH(a) : The thyroid and its diseases, 1948, J. B. Lippincott Company, Philadelphia, p. 324. (b) Werner, S.: The thyroid, 1955, Hoeber-Harper, New York, p. 458. (c) Levitt, T.: The thyroid, 1954, E. and S. Livingstone, Ltd., Edinburgh and London, p. 351. (d) McGavack, T. H.: The thyroid, 1951, C. V. Mosby Company, St. Louis, p. 481. Google Scholar3. Personal communication to the authors from Dr. F. Raymond Keating, Jr., Mayo Clinic, Rochester, Minnesota. Google Scholar4. CookLuty LSM: Koilonychia and its recovery in cases of thyrotoxicosis, Brit. M. J. 2: 207, 1944. CrossrefMedlineGoogle Scholar5. Haines SF: The early diagnosis of exophthalmic goiter, J. Michigan M. Soc. 28: 740, 1929. Google Scholar6. Pardo-Castello V(a) : Diseases of the nails, 1936, Charles C Thomas, Springfield, Illinois. (b) Fox, E. C.: Diseases of the nails: report of cases of onycholysis, Arch. Dermat. and Syph. 41: 98, 1940. (c) White, C. J.: Diseases of the nails, Ciba Clinical Symposia 2: No. 5, 1950. (d) Strauss, M. J.: Onycholysis and onychomadesis, Arch. Dermat. and Syph. 26: 644, 1932. (e) Heimann, H., and Silverberg, M. G.: Onycholysis in fur workers, Arch. Dermat. and Syph. 44: 426, 1941. (f) Viecelli, J. D.: Onycholysis, Arch. Dermat. and Syph. 33: 697, 1936. (g) Sather, E. R.: Onycholysis as occupational disease, Indust. Med. and Surg. 13: 229, 1944. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication July 19, 1957.From the Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore.Requests for reprints should be addressed to Samuel P. Asper, Jr., M.D., The Johns Hopkins Hospital, Baltimore 5, Maryland. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThyroid Gland SignsSeries: Diagnosis at a GlancePlummer's Nails (Onycholysis) in a Thyroid-stimulation-blocking Antibody (TSBAb)-positive Patient with HypothyroidismLe unghie di Plummer o onicolisi nell'ipertiroidismoNails in Systemic DiseaseNail abnormalities associated with systemic pathologiesThe Nail in Systemic DiseaseSecondary structural changes of proteins in fingernails of chronic fatigue syndrome patients from Fourier-transform infrared spectraBrittle NailsNails in Systemic DiseaseNail changes due to diabetes and other endocrinopathiesTrophic Implications of Altered Body Composition Observed in or Near the Nails of Hemodialysis PatientsOnycholysis and Thyroid Disease: Report of Three CasesThe ThyroidEndocrine-skin interactionsNails in Systemic DiseaseUnusual skin eruption with eosinophilia associated with hyperthyroidismHyperthyroidismDAVID H. SOLOMON, M.D., F.A.C.P., L. ROBERT BENNETT, M.D., JOSIAH BROWN, M.D., J. B. PETER, M.D., PH.D., WILLIAM F. POLLOCK, M.D., JOHN B. RICHARDS, M.D.Unusual Manifestations of Graves's DiseaseTHYROTOXICOSIS.CURRENT TRENDS IN THE MANAGEMENT OF THYROID DISEASE 1 July 1958Volume 49, Issue 1Page: 102-108KeywordsHyperthyroidism Issue Published: 1 July 1958 PDF downloadLoading ...