GLUCOSE NEPHROSIS WITH RENAL FAILURE IN A PATIENT WITH LAENNEC'S CIRRHOSIS
Authors: K F GOLDEN, J T PRIOR
Journal: Annals of Internal Medicine (1953)

Case Reports1 December 1953GLUCOSE NEPHROSIS WITH RENAL FAILURE IN A PATIENT WITH LAENNEC'S CIRRHOSISKENNETH F. GOLDEN, M.D., JOHN T. PRIOR, M.D.KENNETH F. GOLDEN, M.D.Search for more papers by this author, JOHN T. PRIOR, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-39-6-1308 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptA characteristic type of renal tubular epithelial damage has been described in both man and experimental animals following the intravenous administration of hypertonic sucrose solutions. This kidney lesion, generally known as "sucrose nephrosis," has been observed in association with other sugars in hypertonic solution including xylose, inulin and glucose. It has also been reported to have occurred in man following such substances in hypertonic solutions as acacia, creatinine, sodium sulfate and urea. Although repeated injections of hypertonic sucrose at frequent intervals can effect significant interference with renal function in man, it is generally considered that the renal lesion produced by...Bibliography1. Helmholz HF: Renal changes in the rabbit resulting from intravenous injection of hypertonic solution of sucrose, J. Pediat. 3: 144-157, 1933. CrossrefGoogle Scholar2. LindbergWaldBarker HAMHMH: Renal changes following administration of hypertonic solutions, Arch. Int. Med. 63: 907-918, 1939. CrossrefGoogle Scholar3. Cutler HH: Effects of sucrose on the kidney, Proc. Staff Meet., Mayo Clin. 14: 318-320, 1939. Google Scholar4. AndersonBethea WAWR: Renal lesions following administration of hypertonic solutions of sucrose, J. A. M. A. 114: 1983-1987, 1940. Google Scholar5. Anderson WA: Sucrose nephrosis and other types of renal tubular injuries, South. M. J. 34: 257-261, 1941. CrossrefGoogle Scholar6. Berthoud E: Les grandes injections intraveineuses de glucose en solutions hypertoniques sont-elles nocives pour le rein? Rev. méd. de la Suisse Rom. 70: 298-305, 1950. MedlineGoogle Scholar7. Wilmer HA: The mechanism of sucrose damage of the kidney tubules, Am. J. Physiol. 141: 431-438, 1944. CrossrefGoogle Scholar8. Allen AC: The kidney, medical and surgical diseases, 1951, Grune and Stratton, New York, p. 212. Google Scholar9. RigdonCardwell RHES: Renal lesions following the intravenous injection of hypertonic solution of sucrose, Arch. Int. Med. 69: 670-690, 1942. CrossrefGoogle Scholar10. MurphyHershbergKatz FDRAAM: The effect of intravenous injections of sucrose solution (50%) on the cerebro-spinal fluid pressure, the blood pressure and clinical course in cases of chronic hypertension, Am. J. M. Sc. 192: 510-517, 1936. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Syracuse, N. Y.*Received for publication May 29, 1953.From the Departments of Medicine and Pathology, State University of New York Medical Center at Syracuse, Syracuse, N. Y. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byF�hrt die sog. osmotische Nephrose oder Zuckerspeicherniere zur Niereninsuffizienz?Zur Kritik der NierenfunktionsprüfungenErkennung und Behandlung anurischer StörungenDiseases of Medical ProgressThe Treatment of Acute Traumatic Renal Insufficiency 1 December 1953Volume 39, Issue 6Page: 1308-1315KeywordsCreatinineGlucoseKidneysLesionsRenal failureSodiumSucroseSulfatesUreaXylose ePublished: 1 December 2008 Issue Published: 1 December 1953 PDF downloadLoading ...