SERUM GLUTAMIC OXALACETIC TRANSAMINASE LEVELS IN 266 SURGICAL PATIENTS
Authors: P R AYRES, T B WILLIARD
Journal: Annals of Internal Medicine (1960)

Article1 June 1960SERUM GLUTAMIC OXALACETIC TRANSAMINASE LEVELS IN 266 SURGICAL PATIENTSPERRY R. AYRES, M.D., F.A.C.P., THOMAS B. WILLIARD, M.D.PERRY R. AYRES, M.D., F.A.C.P.Search for more papers by this author, THOMAS B. WILLIARD, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-52-6-1279 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn 1955 Karmen, Wróblewski, and LaDue1 reported an accurate and simplified technic for the study of enzymes concerned with transamination of amino acids in human tissues. Of several enzymes studied, glutamic oxalacetic transaminase (GO-T) has been given the most attention, and estimation of its level in serum (SGO-T) has been widely accepted as an aid in the diagnosis of acute myocardial infarction. Determination of SGO-T levels has become one of the standard procedures available in the laboratories of most general hospitals.SGO-T determination in patients suspected of myocardial infarction is especially valuable when clinical and electrocardiographic data are inconclusive. Because...Bibliography1. KarmenWróblewskiLaDue AFJS: Transaminase activity in human blood, J. Clin. Investigation 34: 126-133, 1955. CrossrefMedlineGoogle Scholar2. Conrad F: Transaminase, New England J. Med. 256: 602-608 (Mar. 28) 1957. CrossrefMedlineGoogle Scholar3. CohenHekhuis PPGL: Rate of transamination in normal human tissues, J. Biol. Chem. 140: 711-724, 1941. CrossrefGoogle Scholar4. WróblewskiLaDue FJS: Serum glutamic oxalacetic transaminase activity as an index of liver cell injury: a preliminary report, Ann. Int. Med. 43: 345-360, 1955. LinkGoogle Scholar5. ChinskySchmagranoffSherry MGLS: Serum transaminase activity; observations in a large group of patients, J. Lab. and Clin. Med. 47: 108-118, 1956. MedlineGoogle Scholar6. PersonJudge DDRD: Effect of operation on serum transaminase levels, Arch. Surg. 77: 892-897, 1958. CrossrefGoogle Scholar7. FiskThomasMaurukas AARGJ: Serum transaminase values after cholecystectomy, hysterectomy and operations on the fractured hip, Am. J. M. Sc. 236: 133-138. CrossrefMedlineGoogle Scholar8. NickellAllbritten WEFF: Serum transaminase content related to tissue injury, Surgery 42: 240-248, 1957. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Columbus, Ohio*Received for publication October 13, 1959.From the Departments of Medicine and Surgery, Mt. Carmel Hospital, Columbus, Ohio.Requests for reprints should be addressed to Perry R. Ayres, M.D., 344 East State Street, Columbus 15, Ohio. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byEvaluation of Hepatic FunctionSurgery in the Patient with Liver DiseaseCardiac Risks and Complications of Noncardiac SurgeryLEE GOLDMAN, M.D.A comparison of the effects of halothane and other anaesthetic agents on hepato-cellular function in patients submitted to elective operationsSerum enzyme data in diagnosis of myocardial infarction during or early after aorta-coronary saphenous vein bypass graft operationsSerum arginino-succinate lyase:Postoperative JaundiceSerum glutamic oxaloacetic transaminase and electrocardiographic changes after myocardial revascularization procedures in patients with coronary artery diseaseClinical and Experimental Observation of Serum Enzyme Changes Occurring after Surgical Myocardial RevascularizationEnzyme changes following direct current countershockSerum enzyme changes after major lung surgery--with and without halothanePostoperative Serum Glutamic-Oxalacetic Transaminase and Glutamic-Pyruvic Transaminase Changes in Biliary PatientsTHE VALUE OF SERUM CREATINE PHOSPHOKINASE ESTIMATIONS IN THE DIAGNOSIS OF MYOCARDIAL INFARCTIONDiagnosis of experimental intraoperative myocardial infarction by measurement of certain enzymesCardiac complications of phaeochromocytoma.Serum Enzymology in the Diagnosis of Myocardial Infarction and Related Cardiovascular ConditionsSerum enzyme changes with obstructive jaundice and hypotensionPLASMA-TRANSAMINASE LEVELS IN CARDIAC SURGERY WITH EXTRACORPOREAL CIRCULATIONStability of hepatic metabolism during surgeryNebenwirkungen, Nebenerscheinungen und unerwünschte Frühfolgen bei chirurgischen Maßnahmen in der BauchhöhleSerum Enzymes after Cardiac SurgerySERUM TRANSAMINASE RESPONSE TO CARDIAC SURGERY USING CARDIOPULMONARY BYPASSClinically Unrecognized Myocardial Infarction Following Surgery 1 June 1960Volume 52, Issue 6Page: 1279-1288KeywordsAmino acidsAminotransferasesBiliary systemElectrocardiographyEnzymesGratitudeHospital medicineMotivationMyocardial infarctionSurgery ePublished: 1 December 2008 Issue Published: 1 June 1960 PDF downloadLoading ...