THE CLINICAL SYMPTOMS AND SIGNS OF VITAMIN B COMPLEX DEFICIENCY
Authors: William H. Sebrell
Journal: Annals of Internal Medicine (1941)

Article1 December 1941THE CLINICAL SYMPTOMS AND SIGNS OF VITAMIN B COMPLEX DEFICIENCYWILLIAM H. SEBRELL, M.D., F.A.C.P.WILLIAM H. SEBRELL, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-15-6-953 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe symptoms caused by deficiencies in various members of the vitamin B complex probably constitute our greatest medical problem in the deficiency field. There are eight known substances which may be called members of the vitamin B complex. These are thiamin, riboflavin, nicotinic acid, pyridoxine, pantothenic acid, p-aminobenzoic acid, choline and inositol. At least four of these appear to be needed by man. These are thiamin, riboflavin, nicotinic acid and pyridoxine. Deficiencies in the remaining known members of the B complex have been shown to cause various symptoms in experimental animals.It has been shown that a deficiency in pantothenic...References1. DAFTSEBRELL FSWH: Hemorrhagic adrenal necrosis in rats on deficient diets, Pub. Health Rep., 1939, liv, 2247. CrossrefGoogle Scholar2. ANSBACHER S: p-Aminobenzoic acid, a vitamin, Science, 1941, xciii, 164. CrossrefGoogle Scholar3. SPIESBEANASHE TDWBWF: A note on the use of vitamin B6 in human nutrition, Jr. Am. Med. Assoc., 1939, cxii, 2414. CrossrefGoogle Scholar4. SPIESHIGHTOWERHUBBARD TDDPLH: Some recent advances in vitamin therapy, Jr. Am. Med. Assoc., 1940, cxv, 292. CrossrefGoogle Scholar5. JOLLIFFE N: Clinical aspects of vitamin B deficiencies, Minnesota Med., 1940, xxiii, 542. Google Scholar6. WEISSWILKINS SRW: The nature of the cardiovascular disturbances in nutritional deficiency states (beriberi), ANN. INT. MED., 1937, xi, 104. LinkGoogle Scholar7. 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Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Bethesda, Maryland*Read at the Boston meeting of the American College of Physicians, April 23, 1941.†Chief, Division of Chemotherapy, National Institute of Health, U. S. Public Health Service, Bethesda, Maryland. Nextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDeficiency glossitisOral aspect of vitamin B complex deficiencyComparative study of oral changes in dogs due to deficiencies of pantothenic acid, nicotinic acid, and unknowns of the B vitamin complex 1 December 1941Volume 15, Issue 6Page: 953-958KeywordsB vitaminsChemotherapyMedical servicesNiacinPrevention, policy, and public healthPyridoxineRiboflavinSigns and symptomsThiamine ePublished: 1 December 2008 Issue Published: 1 December 1941 Copyright & PermissionsCopyright, 1942, by The American College of PhysiciansPDF downloadLoading ...