SEVERE INFECTIOUS MONONUCLEOSIS TREATED WITH PREDNISOLONE
Authors: M C CREDITOR, H W McCURDY
Journal: Annals of Internal Medicine (1959)

Case Reports1 January 1959SEVERE INFECTIOUS MONONUCLEOSIS TREATED WITH PREDNISOLONEMORTON C. CREDITOR, M.D., HARRY W. MCCURDY, M.D.MORTON C. CREDITOR, M.D.Search for more papers by this author, HARRY W. MCCURDY, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-50-1-218 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptInfectious mononucleosis is a disease of undetermined etiology which generally pursues a benign course. Consideration of specific therapy is rarely required. However, fatalities due to infectious mononucleosis have been reported. Fatal cases include those with complications such as Guillain-Barrésyndrome,1 diffuse neurologic involvement,2 respiratory obstruction,3 splenic rupture4 and generalized "toxemia."5Treatment of infectious mononucleosis is symptomatic. However, reports of cortisone- and corticotropin-treated mononucleosis can be found in the literature. In many, treatment was started because of serious complications in which death seemed imminent; these included neurologic involvement,6respiratory obstruction7and generalized "toxemia."8In each situation a prompt and dramatic response to...Bibliography1. RickerBlumbergPetersWiderman WACHA: The association of the Guillain-Barré syndrome with infectious mononucleosis, with a report of two fatal cases, Blood 2: 217-226, 1947. CrossrefMedlineGoogle Scholar2. DolgopolHusson VBGS: Infectious mononucleosis with neurological complications. Report of a fatal case, Arch. Int. Med. 83: 179-196, 1949. CrossrefGoogle Scholar3. CusterSmith RPEB: The pathology of infectious mononucleosis, Blood 3: 830-856, 1948. CrossrefMedlineGoogle Scholar4. SmithCuster EBRP: Rupture of the spleen in infectious mononucleosis, Blood 1: 317-333, 1946. CrossrefMedlineGoogle Scholar5. ShintonHawkins NKCL: A fatal case of glandular fever, Lancet 2: 708-709, 1956. CrossrefGoogle Scholar6. FieseCheuRadding MJSJ: Guillain-Barré syndrome in infectious mononucleosis. Report of a case with recovery following administration of cortisone, Arch. Int. Med. 92: 438-441, 1953. CrossrefGoogle Scholar7. MandelMarilleyGaines WRJLM: Corticotropin in severe anginose infectious mononucleosis, J. A. M. A. 158: 1021-1022, 1955. CrossrefMedlineGoogle Scholar8. DoranWeisberger JKAS: The use of ACTH in infectious mononucleosis, Ann. Int. Med. 38: 1058-1062, 1953. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication July 1, 1957.From the Sections of Medicine and Otolaryngology, Washington Clinic, The James F. Mitchell Foundation for Research and Education, and the Medical Service, Emergency Hospital, Washington, D. C.Requests for reprints should be addressed to Morton C. Creditor, M.D., Director, Medical Education and Research, The Menorah Medical Center, 4949 Rockhill Road, Kansas City 10, Missouri. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySteroids for symptom control in infectious mononucleosisCochrane Review: Steroids for symptom control in infectious mononucleosisCommentary on ‘Steroids for symptom control in infectious mononucleosis (Review)’ with a response from the review authorsSteroids for symptom control in infectious mononucleosisSteroids for symptom control in infectious mononucleosisDo Systemic Corticosteroids Effectively Treat Obstructive Sleep Apnea Secondary to Adenotonsillar Hypertrophy?Case Report: Transverse Myelitis Associated With Epstein-Barr Virus InfectionSteroids for airway problems in glandular feverUpper Airway Obstruction in Infectious MononucleosisInfectious MononucleosisThrombocytopenic purpura with infectious mononucleosisTreatment of Infectious MononucleosisHAROLD R. SCHUMACHER, WILLIAM A. JACOBSON, CARL R. BEMILLER, M.D.Chloroquine in the Treatment of Infectious MononucleosisRAY G. COWLEY, JOHN E. MYERS JR.Corticotropin and Corticosteroids in Human Viral InfectionsLaryngeal Obstruction in ChildrenViral EncephalitisBenign Duodeno-Colic FistulaeSteroid Therapy in Glandular Fever 1 January 1959Volume 50, Issue 1Page: 218-222KeywordsEtiologyHospital medicineInfectious diseasesMedical educationMedical servicesRespiratory system proceduresUpper respiratory tract infections ePublished: 1 December 2008 Issue Published: 1 January 1959 PDF downloadLoading ...