Mucinous Appendiceal Adenocarcinoma Presenting 5 Years after Appendectomy
Authors: Michael A. Thompson
Journal: Annals of Internal Medicine (2004)

Letters20 April 2004Mucinous Appendiceal Adenocarcinoma Presenting 5 Years after AppendectomyMichael A. Thompson, MD, PhD, Rendell W. Ashton, MD, and Henry C. Pitot, MDMichael A. Thompson, MD, PhDFrom Mayo Clinic, Rochester, MN 55905.Search for more papers by this author, Rendell W. Ashton, MDFrom Mayo Clinic, Rochester, MN 55905.Search for more papers by this author, and Henry C. Pitot, MDFrom Mayo Clinic, Rochester, MN 55905.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-140-8-200404200-00037-w3 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Appendiceal cancer is rare, accounting for less than 0.4% of all intestinal neoplasms (1). Pseudomyxoma peritonei was first described by Werth in 1884 in association with a benign ovarian cystadenoma (2). The term pseudomyxoma peritonei is now used to describe a low-grade mucinous neoplasm of gastrointestinal or ovarian origin. Pseudomyxoma peritonei is a slowly progressive and often recurring disease that characteristically spreads not through blood or lymphatic vessels but through diffuse peritoneal extension (3). We describe a unique case of pseudomyxoma peritonei presenting 5 years after appendectomy. This case also demonstrates the importance of antibiotic treatment in ...References1. Hesketh KT. The management of primary adenocarcinoma of the vermiform appendix. Gut. 1963;4:158-68. [PMID: 13954206] CrossrefMedlineGoogle Scholar2. Werth R. Pseudomyxoma peritonei. Arch Gynecol Obstet. 1884;24:100-8. Google Scholar3. Gough DB, Donohue JH, Schutt AJ, Gonchoroff N, Goellner JR, Wilson TO, et al . Pseudomyxoma peritonei. Long-term patient survival with an aggressive regional approach. Ann Surg. 1994;219:112-9. [PMID: 8129481] CrossrefMedlineGoogle Scholar4. Nitecki SS, Wolff BG, Schlinkert R, Sarr MG. The natural history of surgically treated primary adenocarcinoma of the appendix. Ann Surg. 1994;219:51-7. [PMID: 8297177] CrossrefMedlineGoogle Scholar5. Sugarbaker PH, Kern K, Lack E. Malignant pseudomyxoma peritonei of colonic origin. Natural history and presentation of a curative approach to treatment. Dis Colon Rectum. 1987;30:772-9. [PMID: 2820671] CrossrefMedlineGoogle Scholar6. Sugarbaker PH, Landy D, Jaffe G, Pascal R. Histologic changes induced by intraperitoneal chemotherapy with 5-fluorouracil and mitomycin C in patients with peritoneal carcinomatosis from cystadenocarcinoma of the colon or appendix. Cancer. 1990;65:1495-501. [PMID: 2107021] CrossrefMedlineGoogle Scholar7. Landen S, Bertrand C, Maddern GJ, Herman D, Pourbaix A, de Neve A, et al . Appendiceal mucoceles and pseudomyxoma peritonei. Surg Gynecol Obstet. 1992;175:401-4. [PMID: 1440166] MedlineGoogle Scholar8. Haid M, Bowie L, Kim D, Khandekar JD, Victor TA. Peritoneal washing therapy for pseudomyxoma peritonei. South Med J. 1981;74:913-5. [PMID: 6455738] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Mayo Clinic, Rochester, MN 55905. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPseudomyxoma PeritoneiPseudomyxoma Peritonei: Is Disease Progression Related to Microbial Agents? A Study of Bacteria, MUC2 and MUC5AC Expression in Disseminated Peritoneal Adenomucinosis and Peritoneal Mucinous Carcinomatosis 20 April 2004Volume 140, Issue 8Page: W-33KeywordsAbdominal painAdenocarcinomaAntibioticsAppendectomyCancer treatmentColectomyComputed axial tomographyLesionsRadiation therapySurgery ePublished: 20 April 2004 Issue Published: 20 April 2004 Copyright & PermissionsCopyright © 2004 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...