A HEMODYNAMIC STUDY OF HYPERTENSION INCLUDING OBSERVATIONS ON CORONARY BLOOD FLOW
Authors: G G ROWE, C A CASTILLO, G M MAXWELL, C W CRUMPTON
Journal: Annals of Internal Medicine (1961)

Article1 March 1961A HEMODYNAMIC STUDY OF HYPERTENSION INCLUDING OBSERVATIONS ON CORONARY BLOOD FLOWGEORGE G. ROWE, M.D., F.A.C.P., CESAR A. CASTILLO, M.D., GEORGE M. MAXWELL, M.D., M.R.C.P., CHARLES W. CRUMPTON, M.D.GEORGE G. ROWE, M.D., F.A.C.P., CESAR A. CASTILLO, M.D., GEORGE M. MAXWELL, M.D., M.R.C.P., CHARLES W. CRUMPTON, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-54-3-405 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptMany studies of the systemic hemodynamics of arterial hypertension have been done, both in the experimental animal and in man, and these have recently been reviewed by Fries.1 The specific data concerning cardiac output in man have been expanded and reviewed recently by Varnauskas2 and by Taylor et al.3 However, there is much less information available concerning coronary blood flow in hypertensive subjects.4 The present study was done to add information concerning both systemic and coronary hemodynamics in subjects with both mild and severe hypertension.MATERIAL AND METHODSTwenty-one hypertensive subjects were studied by cardiac catheterization. These subjects were not...Bibliography1. Fries ED: Hemodynamics of hypertension. Physiol. Rev. 40: 27, 1960. CrossrefMedlineGoogle Scholar2. Varnauskas E: Studies in hypertensive cardiovascular disease with special reference to cardiac function. Scand. J. Clin. Lab. Invest. 7: (Supplement 17) 1, 1955. MedlineGoogle Scholar3. TaylorDonaldBishop SHKWJM: Circulatory studies in hypertensive patients at rest and during exercise. Clin. Science 16: 351, 1957. MedlineGoogle Scholar4. Bing RJ: The coronary circulation in health and disease as studied by coronary sinus catheterization. Bull. N. Y. Acad. Med. 27: 405, 1951. Google Scholar5. SmithwickBushKinsey RHRDD: Hypertension and associated cardiovascular disease. J. A. M. A. 160: 1023, 1956. CrossrefMedlineGoogle Scholar6. RoweCastilloMaxwellCrumpton GGCAGMCW: Comparison of systemic and coronary hemodynamics in the normal human male and female. Circulat. Res. 7: 728, 1959. CrossrefMedlineGoogle Scholar7. BlumgartWeiss HLS: Studies on the velocity of blood flow. IV. The velocity of blood flow and its relation to other aspects of the circulation in patients with arteriosclerosis and in patients with arterial hypertension. J. Clin. Invest. 4: 173, 1927. CrossrefMedlineGoogle Scholar8. Gladstone SA: Cardiac output and arterial hypertension, pp. 33-40, 1935. New York, (published by author). Google Scholar9. BolomeyMichieMichieBreedSchreinerLauson AAAJCESGEHD: Simultaneous measurement of effective renal blood flow and cardiac output in resting normal subjects and patients with benign essential hypertension. J. Clin. Invest. 28: 10, 1949. CrossrefGoogle Scholar10. BrandfonbrenerLandowneShock MMN: Changes in cardiac output with age. Circulation 7: 557, 1955. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: GEORGE G. ROWE, M.D., F.A.C.P.; CESAR A. CASTILLO, M.D.; GEORGE M. MAXWELL, M.D., M.R.C.P.; CHARLES W. CRUMPTON, M.D.Affiliations: Madison, Wisconsin*Received for publication Sept. 21, 1960.From the Cardiopulmonary Research Laboratory and the Department of Medicine, University of Wisconsin Medical School.†Supported in part by grants from the Wisconsin Heart Association, the National Heart Institute, U. S. Public Health Service, and the Wisconsin Alumni Research Foundation.Presented at the Regional Meeting of The American College of Physicians, September 24, 1960, Chicago, Illinois.Requests for reprints should be addressed to George G. Rowe, M.D., F.A.C.P., University Hospitals, The University of Wisconsin, 1300 University Avenue, Madison 6, Wisconsin. 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Current research and recommendations from the Subgroup on Local Hemodynamics.ReferencesZentrale Hämodynamik und Herzfunktion bei HypertoniePathophysiological mechanisms in essential hypertensionA comparison of the size of the arterial vascular bed to the right ventricular mass in patients with chronic obstructive pulmonary diseaseEffects of cardiac hypertrophy secondary to hypertension on the coronary circulationEffects of exercise on blood flow in the hypertrophied heartLiteraturEffect of renal hypertension and left ventricular hypertrophy on the coronary circulation in dogs.Ventrikelfunktion und koronare Hämodynamik bei der essentiellen HypertonieSplanchnic blood flow in essential hypertension and in hypertensive patients with renal artery stenosis.Atherosclerosis Complicating Chronic HypertensionDivergent effects of antihypertensive therapy on cardiovascular responses and left ventricular function during upright exerciseTechniques to measure coronary blood flow in manHemodynamic Effects of Oxygen Breathing in Systemic Arterial HypertensionMyocardial blood flow and oxygen uptake in clinical and experimental cardiomegalyUntersuchungen zum Verhalten des Pulmonalkreislaufs bei arterieller HypertonieKreislaufmechanik bei essentieller und renovaskulärer HypertonieReferencesA Hemodynamic Comparison of Essential and Renovascular HypertensionHämodynamische Untersuchungen bei fixierter essentieller HypertonieMeasurement of Coronary Blood Flow by External Counting with Radioactive RubidiumHemodynamic Patterns in Essential HypertensionMITRAL STENOSIS AND LEFT VENTRICULAR FAILURESome considerations of coronary flowThe Regulation of Coronary Blood Flow in Man in Normal and Abnormal ConditionsTreatment of hypertension with coronary and cerebral arteriosclerosis∗Hemodynamic alterations accompanying diastolic hypertension∗ 1 March 1961Volume 54, Issue 3 Page: 405-412 Keywords Blood Blood flow Cardiac output Catheterization Heart Hemodynamics Hypertension Information technology Medical services Research laboratories ePublished: 1 December 2008 Issue Published: 1 March 1961 PDF downloadLoading ...