CRYOGLOBULINEMIA: A CASE REPORT
Authors: D P BARR, R L ENGLE, E M RUSS
Journal: Annals of Internal Medicine (1957)

Case Reports1 December 1957CRYOGLOBULINEMIA: A CASE REPORTDAVID P. BARR, M.D., M.A.C.P., RALPH L. ENGLE JR., M.D., ELLA M. RUSS, B.S., D.SC.DAVID P. BARR, M.D., M.A.C.P.Search for more papers by this author, RALPH L. ENGLE JR., M.D.Search for more papers by this author, ELLA M. RUSS, B.S., D.SC.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-47-6-1225 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe following case report illustrates difficulties that may be encountered when a large amount of cold precipitable globulin circulates in the blood of a patient with the malady which has been called cryoglobulinemia.1, 2CASE REPORTA single man of 50 was referred to The New York Hospital by Dr. Robert Nickau, of Jacksonville, Florida. He had been well until 1946, when he noted severe aching pain in his fingers. This became more severe on exposure to cold and subsided when he was in a hot environment. During the winter the pain was more persistent and was accompanied by intense...Bibliography1. LernerWatson ABCJ: Studies of cryoglobulins. I. Unusual purpura associated with the presence of a high concentration of cryoglobulin (cold precipitable serum globulin), Am. J. M. Sc. 214: 410, 1947. CrossrefMedlineGoogle Scholar2. BarrReaderWheeler DPGGCH: Cryoglobulinemia. I. Report of two cases with discussion of clinical manifestations, incidence and significance, Ann. Int. Med. 32: 6, 1950. LinkGoogle Scholar3. PutnamMiyake FWA: Proteins in multiple myeloma, Arch. Biochem. and Biophys. 65: 39, 1956. CrossrefMedlineGoogle Scholar4. EngleBarr RLDP: Multiple myeloma treated with ACTH, Second Clinical ACTH Conference, Volume II (Therapeutics), 1951, The Blakiston Company, New York, p. 209. Google Scholar5. LernerGreenberg ABGR: A homomolecular serum protein with anomalous solubilities, J. Biol. Chem. 162: 429, 1946. CrossrefMedlineGoogle Scholar6. Cugudda E: Plasmocitoma con crioglobulinemia e trombosi arteriose e venose multiple, Minerva med. 43: 205, 1952. MedlineGoogle Scholar7. Rorock K: Cryoglobulinemia, Acta med. Scandinav. 137: 390, 1950. MedlineGoogle Scholar8. MuirheadMontgomeryGordon EEPOCE: Thromboembolic pulmonary vascular sclerosis, Arch. Int. Med. 89: 41, 1952. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Received for publication May 4, 1957.Requests for reprints should be addressed to R. L. Engle, Jr., M.D., New York Hospital, 525 East 68th Street, New York 21, N. Y. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byRaynaud syndromeDigital arteritis as a presenting feature of malignant diseaseBiologic and clinical significance of cryoglobulinsParaproteinämische HämoblastosenUnusual findings in the human renal glomerulus in multiple myelomaPurpura, Arthralgia, and IgM-IgG Cryoglobulinemia with Rheumatoid Factor Activity Response to Cyclophosphamide and SplenectomyDAVID A. MATHISON, M.D., JOHN J. CONDEMI, M.D., F.A.C.P., JOHN P. LEDDY, M.D., MARY LOU CALLERAME, M.D., BERNARD J. PANNER, M.D., JOHN H. VAUGHAN, M.D., F.A.C.P.Pathology of the Kidney in Waldenström's MacroglobulinemiaNiere bei Tumoren, Blutkrankheiten und ParaproteinämienAggregation of IgG globulin in vivoEin Fall von Makrokryoglobulin�mie mit vor�bergehend reversiblen SymptomenPlasma-Cell MyelomaDie Pathomorphologie der Nierenausscheidung 1 December 1957Volume 47, Issue 6Page: 1225-1234KeywordsBloodBlood plasmaGlobulinsIschemiaMeningitisMyelomaProteinsProteinuriaThrombosisUlcers ePublished: 1 December 2008 Issue Published: 1 December 1957 PDF downloadLoading ...