Ocular Venous Occlusion and Hyperhomocysteinemia
Authors: Didier Ducloux, Catherine Bresson-Vautrin, Jean-Marc Chalopin
Journal: Annals of Internal Medicine (1999)

Letters5 October 1999Ocular Venous Occlusion and HyperhomocysteinemiaDidier Ducloux, MD, Catherine Bresson-Vautrin, MD, and Jean-Marc Chalopin, MDDidier Ducloux, MDSaint Jacques Hospital; Besançon, France (Ducloux)Saint Jacques Hospital; Besançon, France (Bresson-Vautrin)Saint Jacques Hospital; Besançon, France (Chalopin)Search for more papers by this author, Catherine Bresson-Vautrin, MDSaint Jacques Hospital; Besançon, France (Ducloux)Saint Jacques Hospital; Besançon, France (Bresson-Vautrin)Saint Jacques Hospital; Besançon, France (Chalopin)Search for more papers by this author, and Jean-Marc Chalopin, MDSaint Jacques Hospital; Besançon, France (Ducloux)Saint Jacques Hospital; Besançon, France (Bresson-Vautrin)Saint Jacques Hospital; Besançon, France (Chalopin)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-131-7-199910050-00033 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:De Bruijne and colleagues (1) recently reported that 63.6% of 26 patients with venous ocular thrombosis had either fasting hyperhomocysteinemia or elevated post-methionine loading homocysteine concentrations. This association has been previously published (2), and, although a control group is lacking, this observation suggests a relation between hyperhomocysteinemia and venous ocular occlusion. Whether homocysteine-lowering treatment may prevent this complication remains to be determined. We recently observed a case that may help to address this question.A 30-year-old man had been treated by peritoneal dialysis since January 1995 for end-stage renal disease caused by focal and segmental hyalinosis. At ...References1. De Bruijne EL, Keulen-de Vos GH, Ouwendijk RJ. Ocular venous occlusion and hyperhomocysteinemia. Ann Intern Med. 1999;130:78. LinkGoogle Scholar2. Wenzler EM, Rademakers AJ, Boers GH, Cruysberg JR, Webers CA, Deutman AF. Hyperhomocysteinemia in retinal artery and retinal vein occlusion. Am J Ophthalmol. 1993;115:162-7. CrossrefMedlineGoogle Scholar3. Chauveau P, Chadefaux B, Coudé M, Aupetit J, Hannedouche T, Kamoun P, et al . Hyperhomocysteinemia, a risk factor for atherosclerosis in chronic uremic patients. Kidney Int. 1993;43 Suppl 41 S72-7. Google Scholar4. Arnadottir M, Hultberg B, Wahlberg J, Fellstrom B, Dimeny E. Serum total homocysteine concentration before and after renal transplantation. Kidney Int. 1998;54:1380-4. CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Saint Jacques Hospital; Besançon, France (Ducloux)Saint Jacques Hospital; Besançon, France (Bresson-Vautrin)Saint Jacques Hospital; Besançon, France (Chalopin) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoOcular Venous Occlusion and Hyperhomocysteinemia Emile L.E. de Bruijne , Gonneke H.J.C. Keulen-de Vos , and Rob J.Th. Ouwendijk Metrics Cited ByGenes and genetics in hyperhomocysteinemia and the “1-carbon metabolism”: implications for retinal structure and eye functionsB vitamins in stroke prevention: time to reconsiderHomocysteine-lowering therapy: a role in stroke prevention?Meta-analysis of plasma homocysteine, serum folate, serum vitamin B12, and thermolabile MTHFR genotype as risk factors for retinal vascular occlusive diseaseGenetic determinants of fasting and post-methionine hyperhomocysteinemia in patients with retinal vein occlusion 5 October 1999Volume 131, Issue 7Page: 548-549KeywordsAttentionDiabetes mellitusHyperlipidemiaMedical dialysisPeritoneal dialysisRenal failureRenal transplantationThrombosisTransplantationVision Issue Published: 5 October 1999 CopyrightCopyright © 1999 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...