Allergic Reaction to Varicella Vaccine
Authors: John Gerecitano
Journal: Annals of Internal Medicine (1997)

Letters15 May 1997Allergic Reaction to Varicella VaccineJohn Gerecitano, MS, Alvin Friedman-Kien, MD, and Geoffrey D. Chazen, MDJohn Gerecitano, MSNew York University Medical Center, New York, NY 10016Search for more papers by this author, Alvin Friedman-Kien, MDNew York University Medical Center, New York, NY 10016Search for more papers by this author, and Geoffrey D. Chazen, MDNew York University Medical Center, New York, NY 10016Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-126-10-199705150-00036 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Two weeks after inoculation with the varicella virus vaccine (Varivax, Merck and Co., Inc., West Point, Pennsylvania), a 26-year-old healthy man who was seronegative for human immunodeficiency virus noticed a 2.0-cm oval-shaped macule on the skin of his left axilla. Ten days after onset of the eruption, about 50 such lesions were counted on the trunk, concentrated in the axillary regions (not at the vaccination site). The pink-red lesions were nonblanching and had a darker red border. The results of punch biopsy were nondiagnostic.During the next 6 weeks, the macular lesions gradually faded as reddish, 1- ...References1. Lungu O, Annunziato PW, Gershon A, Staugatis S, Josephson D, LaRussa P, et al. Reactivation and latent varicella-zoster virus in human dorsal root ganglia. Proc Natl Acad Sci U S A. 1995; 92:10980-4. Google Scholar2. Calabrese LH, Michel BA, Block DA, Arend WP, Edworthy SM, Fauci AS, et al. The American College of Rheumatology 1990 criteria for the classification of hypersensitivity vasculitis. Arthritis Rheum. 1990; 33:1108-13. Google Scholar3. Calabrese LH. Differential diagnosis of hypersensitivity vasculitis. Cleve Clin J Med. 1990; 57:506-7. Google Scholar4. Parums DV. The arteritides. Histopathology. 1994; 25:1-20. Google Scholar5. Michel BA, Hunder GG, Block DA, Calabrese LH. Hypersensitivity vasculitis and Henoch-Schonlein purpura: a comparison between the two disorders. J Rheumatol. 1992; 19:721-8. Google Scholar Author, Article, and Disclosure InformationAuthors: John Gerecitano, MS; Alvin Friedman-Kien, MD; Geoffrey D. Chazen, MDAffiliations: New York University Medical Center, New York, NY 10016 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byA Unique Case Report on Hypersensitivity Vasculitis as an Allergic Reaction to the Herpes Zoster VaccineA case report of leukocytoclastic vasculitis after vaccination in a patient with inflammatory bowel diseaseVaccines, adjuvants and autoimmunityVasculitidesReview of the United States universal varicella vaccination program: Herpes zoster incidence rates, cost-effectiveness, and vaccine efficacy based primarily on the Antelope Valley Varicella Active Surveillance Project dataThe Case against Universal Varicella VaccinationCutaneous Adverse Reactions Following Anti-Infective VaccinationsVaccinesVaricella zoster virus vaccine live 15 May 1997Volume 126, Issue 10Page: 833-834KeywordsBiopsyHypersensitivityLesionsPolymerase chain reactionProteinuriaRashesRheumatologyVaccinesVasculitisViral load ePublished: 15 August 2000 Issue Published: 15 May 1997 Copyright & PermissionsCopyright © 1997 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...