IS PRIMARY HEMORRHAGIC THROMBOCYTHEMIA A CLINICAL MYTH?
Authors: W R McCABE, R M BIRD, R A McLAUGHLIN
Journal: Annals of Internal Medicine (1955)

Case Reports1 July 1955IS PRIMARY HEMORRHAGIC THROMBOCYTHEMIA A CLINICAL MYTH?WILLIAM R. MCCABE, M.D., ROBERT M. BIRD, M.D., ROBERT A. MCLAUGHLIN, M.D.WILLIAM R. MCCABE, M.D.Search for more papers by this author, ROBERT M. BIRD, M.D.Search for more papers by this author, ROBERT A. MCLAUGHLIN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-43-1-182 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTransitory thrombocytosis is seen following splenectomy, during the postpartum period and accompanying certain infections and malignant processes.1More persistent elevations of circulating blood platelets, that is, thrombocythemia, are occasionally seen in polycythemia rubra vera2and chronic myelogenous leukemia.3In addition, 13 cases have been reported in the literature in which a persistent thrombocythemia was attributed to a primary dyscrasia of the megakaryocytes and platelets. This syndrome has been referred to as primary hemorrhagic thrombocythemia. We wish to present another case in which the diagnosis of primary hemorrhagic thrombocythemia was made. It was possible to follow this patient throughout the entire...Bibliography1. Wintrobe MM: Clinical hematology, 3rd Ed., 1951, Lea & Febiger, Philadelphia. Google Scholar2. DameshekHenstell WHH: The diagnosis of polycythemia, Ann. Int. Med. 13: 1360, 1940. LinkGoogle Scholar3. MinotBuckman GRTE: The blood platelets in the leukemias, Am. J. M. Sc. 169: 477, 1925. CrossrefGoogle Scholar4. EpsteinGoedel EA: Hämorrhagische Thrombocythämie bei vasculärer Schrumpfmilz, Virchows Arch. f. path. Anat. 292: 233, 1934. CrossrefGoogle Scholar5. EpsteinKretz EJ: Über einen Fall von hochgradiger Thrombocytenvermehrung, Klin. Wchnschr. 9: 1177, 1930. CrossrefGoogle Scholar6. Uotila U: On hemorrhagic thrombocythemia, Acta med. Scandinav. 95: 136, 1938. CrossrefGoogle Scholar7. Di Guglielmo G: Eritroleucemia e piastrinemia, Folia med. 1: 36, 1920. Google Scholar8. Reid J: Hemorrhagic thrombocythemia, Lancet 2: 584, 1940. CrossrefGoogle Scholar9. RowlandsVaizey RAJM: Primary thrombocythemia, Lancet 2: 1217, 1938. CrossrefGoogle Scholar10. Lebel H: Case of hemorrhagic thrombocythemia, Nord. med. 33: 303, 1947. Google Scholar11. Mortenson O: Thrombocythemia hemorrhagica, Acta med. Scandinav. 129: 547, 1948. CrossrefMedlineGoogle Scholar12. Drake CB: Leukemia with thrombocytosis, J. A. M. A. 106: 1005, 1936. CrossrefGoogle Scholar13. AkazakiHamaguchi KI: Ein Fall von Thrombocythämie, Beitr. z. path. Anat. u. z. allg. Path. 103: 95, 1939. Google Scholar14. SpangbergZettergren JL: A case of thrombocythemia essentialis, Acta med. Scandinav. 135: 176, 1949. Google Scholar15. Owren P: Thrombocytémie essentielle, Gastroenterologia 68: 148, 1943. CrossrefGoogle Scholar16. Holst JE: Hemorrhagical thrombocythemia, Acta med. Scandinav. 130: 507, 1948. CrossrefMedlineGoogle Scholar17. BlockJacobsonBethard MLOWF: Preleukemic acute human leukemia, J. A. M. A. 152: 1018, 1953. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Oklahoma City, Oklahoma*Received for publication June 22, 1954.From the Departments of Medicine and Pathology, University of Oklahoma School of Medicine, and University Hospitals, Oklahoma City, Oklahoma. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe Myeloproliferative Disorders an Historical Appraisal and Personal ExperiencesThrombocytosis and Thrombocythemia9 Essential thrombocythaemiaAcute transformation of essential thrombocythaemia: report of two cases.Acute basophilic leukemiaESSENTIAL THROMBOCYTHEMIA WITH TRANSITION INTO ACUTE LEUKEMIAMegakaryocyte Quantifications in Relation to Thrombokinetics in Primary Thrombocythaemia and Allied DiseasesThrombocytosis and ThrombocythemiaIdiopathic Thrombocythaemia: A Review of Seven Cases in Western Australia**The Spectrum of Myeloproliferative DisordersDisseminated Scotochromogen Infection and Unusual Myeloproliferative Disorder Report of a Case and Review of the LiteratureDAVID R. MCNUTT, M.D., H. H. FUDENBERG, M.D.The myeloproliferative disordersElektronenmikroskopische Untersuchungen der Megakaryozyten und Thrombozyten eines Falles von primär hämorrhagischer ThrombozythämieBIBLIOGRAPHYIDIOPATHIC THROMBOCYTHÆMIA PRESENTING WITH ISCHÆMIA OF THE TOES: REPORT OF THREE CASESA case of haemorrhagic thrombocythaemiaPrimary hemorrhagic thrombocythemiaCrepuscular Thrombo-Embolic Syndromes 1 July 1955Volume 43, Issue 1Page: 182-190KeywordsBloodHospital medicineMegakaryocytesPlateletsPolycythemiaSplenectomyThrombocytosisThrombosis ePublished: 1 December 2008 Issue Published: 1 July 1955 PDF downloadLoading ...