Thrombolysis in Heparin-Induced Thrombocytopenia with Thrombosis
Authors: STEVEN K. KRUEGER
Journal: Annals of Internal Medicine (1985)

Letters and Corrections1 July 1985Thrombolysis in Heparin-Induced Thrombocytopenia with ThrombosisSTEVEN K. KRUEGER, M.D., EDWARD ANDRES, M.D., ERNEST WEINAND, M.D.STEVEN K. KRUEGER, M.D., EDWARD ANDRES, M.D., ERNEST WEINAND, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-103-1-159_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Thrombosis associated with thrombocytopenia is a common, life-threatening complication of heparin therapy (1-5). Treatment has been unsatisfactory. We report here the successful treatment with urokinase of a patient with heparin-induced thrombocytopenia and thrombosis.A 57-year-old male smoker who had insulin-dependent diabetes was hospitalized with acute pain in the left hand and arm and a blue-gray, cold, pulseless left arm. Angiography showed total occlusion of the left subclavian artery. Treatment with intra-arterial streptokinase, 5000 U/h, resulted 6 hours later in the thrombosis being dislodged into the brachial artery, but eventually the patient required embolectomy. The hand and arm...References1. SILVER D, KAPSCH D, and TSOI E. Heparin-induced thrombocytopenia, thrombosis, and hemorrhage. Ann Surg. 1983;198:301-6. CrossrefMedlineGoogle Scholar2. ANSELL J and DEKYIN D. Heparin-induced thrombocytopenia and recurrent thromboembolism. Am J Hematol. 1981;8:325-32. CrossrefGoogle Scholar3. BABCOCK R, DUMPER C, and SCHARFMAN W. Heparin-induced immune thrombocytopenia. N Engl J Med. 1976;395:237-40. CrossrefGoogle Scholar4. KING D and KELTON J. Heparin-associated thrombocytopenia. Ann Intern Med. 1984;100:535-40. LinkGoogle Scholar5. WEISMAN R and TOBIN R. Arterial embolism occurring during systemic heparin therapy. Arch Surg. 1958;76:219-27. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: STEVEN K. KRUEGER, M.D.; EDWARD ANDRES, M.D.; ERNEST WEINAND, M.D.Affiliations: Specialists of Internal Medicine, Inc. St. Joseph, MO 64506 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPlatelet count recovery and seroreversion in immune HIT despite continuation of heparin: further observations and literature reviewTreatment of Heparin-Induced ­Thrombocytopenia: An OverviewHirudin therapy during thrombolysis for venous thrombosis in heparin-induced thrombocytopeniaHeparin-Induced ThrombocytopeniaHeparin-induced thrombocytopeniaThe heparin-induced thrombocytopenia and thrombosis syndrome: Treatment with intraarterial urokinase and systemic platelet aggregation inhibitorsThrombolysis to Treat Arterial Thrombotic Complications of Heparin-Induced ThrombocytopeniaHirudin therapy for heparin-associated thrombocytopenia and deep venous thrombosisDrug-Induced Blood DisordersHeparin-induced thrombocytopenia and thrombosis: Reversal with streptokinase a case report and review of literatureA New Manifestation and Treatment Alternative for Heparin-Induced ThrombosisHeparin and PlateletsDrugs affecting blood clotting and fibrinolysis 1 July 1985Volume 103, Issue 1Page: 159-159KeywordsAngiographyArteriesEmbolectomyHeparinHeparin-induced thrombocytopeniaInsulinThrombosis ePublished: 1 December 2008 Issue Published: 1 July 1985 PDF downloadLoading ...