MASCULINIZING CARCINOMA OF THE ADRENAL CORTEX WITH PHYSIOLOGICALLY ACTIVE METASTASES: A CASE REPORT
Authors: R H FITZ, H W TOLL
Journal: Annals of Internal Medicine (1956)

Case Reports1 June 1956MASCULINIZING CARCINOMA OF THE ADRENAL CORTEX WITH PHYSIOLOGICALLY ACTIVE METASTASES: A CASE REPORTREGINALD H. FITZ, M.D., HENRY W. TOLL, M.D.REGINALD H. FITZ, M.D.Search for more papers by this author, HENRY W. TOLL, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-44-6-1231 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptCarcinoma of the adrenal is a relatively unusual neoplasm which may present in various guises, depending on its hormonal activity. The following case presents several common and some unusual features of a predominantly masculinizing carcinoma of the adrenal.‡CASE REPORTA 29 year old married Spanish-American woman entered Denver General Hospital for the second time on September 7, 1949, complaining of nausea, vomiting and left upper quadrant pain of two days' duration. The patient had noted some acne, a rather deep voice, and excessive facial and pubic hair since puberty; these signs had increased considerably during the two years before...Bibliography1. DowningKennedyClarke STJP: Retroperitoneal radiography with oxygen injection, Rocky Mountain M. J. 51: 181-184, 1954. MedlineGoogle Scholar2. TaylorSnow ESRH: Adrenal virilism in the female child and adult, Am. J. Obst. and Gynec. 67: 1307-1320, 1954. CrossrefMedlineGoogle Scholar3. AllenHaywardPinto WMSJA: A color test for dehydroisoandrosterone and closely related steroids, of use in the diagnosis of adrenocortical tumors, J. Clin. Endocrinol. 10: 54-70, 1950. CrossrefGoogle Scholar4. Simpson SL: The adreno-genital syndrome, Post-Grad. M. J. (Lond.) 29: 184-191, 1953. CrossrefMedlineGoogle Scholar5. Miller de PaivaLoboMarcondes da Silva LJIA: Menarche and pregnancy after removal of an adrenocortical adenoma, J. Clin. Endocrinol. 11: 330-337, 1951. CrossrefGoogle Scholar6. 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VenningPatteeMcCallBrowne EHCJFJS: Effect of cortisone on the excretion of 17-ketosteroids in adrenal tumor, J. Clin. Endocrinol. and Metab. 12: 1409-1425, 1952. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Denver, Colorado*Received for publication March 28, 1955.From the Departments of Medicine and Pathology, University of Colorado Medical School and Denver General Hospital, Denver, Colorado.Originally presented at a Combined Regional Meeting of The American College of Physicians and The Colorado Society of Internal Medicine, Colorado Springs, Colorado, January 15, 1955.†Trainee, National Cancer Institute.‡This patient's case was abstracted prior to her death by Downing et al., in a paper on retroperitoneal radiography.1 The case was reported in abbreviated form, again prior to death, by Taylor and Snow,2 in a paper on "Adrenal Virilism in the Female Child and Adult." 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