ELECTROCARDIOGRAPHIC STUDIES IN CLINICAL AND EXPERIMENTAL PULMONARY EMBOLIZATION
Authors: William S. Love, G. W. Brugler, Nathan Winslow
Journal: Annals of Internal Medicine (1938)

Article1 June 1938ELECTROCARDIOGRAPHIC STUDIES IN CLINICAL AND EXPERIMENTAL PULMONARY EMBOLIZATIONWILLIAM S. LOVE JR., M.D., F.A.C.P., G. W. BRUGLER, M.D., NATHAN WINSLOW, M.D.WILLIAM S. LOVE JR., M.D., F.A.C.P.Search for more papers by this author, G. W. BRUGLER, M.D.Search for more papers by this author, NATHAN WINSLOW, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-11-12-2109 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn 1935, McGinn and White1 reported certain aberrations in the electrocardiograms derived from five patients suffering with pulmonary embolization. These deviations from normal were as follows:1. Prominent S-wave and low origin of the T-wave in Lead I, the ST segment starting slightly below the baseline.2. Staircase ascent of the ST segment from the S-wave to the T-wave in Lead II.3. The presence of Q3, and inversion of the T-wave in this lead.4. T-waves of opposite sign to normal in the precordial lead.They considered it probable that the electrocardiographic changes consequent on pulmonary embolism were due...References1. MCGINNWHITE SPD: Acute cor pulmonale resulting from pulmonary embolism, Jr. Am. Med. Assoc., 1935, civ, 1473. CrossrefGoogle Scholar2. SCHERFSCHONBRUNNER DE: Über Herzbefindung bei Lungenembolien, Ztschr. f. klin. Med., 1935, cxxviii, 455. Google Scholar3. HAZARDPALMER JBRS: A case of pulmonary embolism simulating coronary thrombosis in a young man aged thirty-three years, Am. Heart Jr., 1936, xii, 748. CrossrefGoogle Scholar4. LOVEBRUGLER WSGW: Electrocardiograms similar to those of coronary thrombosis with especial reference to those obtained in pulmonary infarction, South. Med. Jr., 1937, xxx, 371. CrossrefGoogle Scholar5. HAGGERTWALKER GEAM: Physiology of pulmonary embolism as disclosed by quantitative occlusion of the pulmonary artery, Arch. Surg., 1923, vi, 764. CrossrefGoogle Scholar6. GIBBONHOPKINSONCHURCHILL JHMED: Changes in the circulation produced by gradual occlusion of the pulmonary artery, Jr. Clin. Invest., 1932, xi, 543. CrossrefGoogle Scholar7. HORINEWARNER CFCG: Experimental occlusion of the pulmonary artery, Arch. Surg., 1934, xxviii, 139. CrossrefGoogle Scholar8. BUCHBINDERKATZ WCLN: The electrocardiogram in acute experimental distention of the right heart, Am. Jr. Med. Sci., 1934, clxxxvii, 785. CrossrefGoogle Scholar9. FARRSPIEGEL CER: Pulmonary infarction and embolism, Ann. Surg., 1929, lxxxix, 481. CrossrefGoogle Scholar10. HAMPTONWHARTON HHLR: Venous thrombosis, pulmonary infarction and embolism following gynecological operations, Bull. Johns Hopkins Hosp., 1920, xxxi, 95. Google Scholar11. WHITEBRENNER PDO: Pathological and clinical aspects of the pulmonary circulation, New England Jr. Med., 1933, ccix, 1261. CrossrefGoogle Scholar12. WIGGERS CJ: Circulation in health and disease, 1934, Lea and Febiger, Philadelphia. Google Scholar13. MANN FC: An experimental study of pulmonary embolism, Jr. Exper. Med., 1917, xxvi, 387. CrossrefGoogle Scholar14. KRUMBHAAR EB: Note on electrocardiographic changes accompanying acutely increased pressure following pulmonary artery ligature, Am. Jr. Med. Sci., 1934, clxxxvii, 792. CrossrefGoogle Scholar15. OTTO HL: The effect of sudden increase in the intracardiac pressure on the form of the electrocardiographic T-wave, Jr. Lab. and Clin. Med., 1929, iv, 643. Google Scholar16. MOSLER E: Über Kreislaufvorgänge bei der Lungenembolie, Med. Klin., 1931, xliii, 1555. Google Scholar17. ANDERSON JP: Abstract, Am. Heart Jr., 1933-34, ix, 104. Google Scholar18. FROMMEL E: Les troubles du rhythm cardiaque au cours de l'embolie pulmonaire mortelle: Étude électrocardiographique expérimentale, Jr. de physiol. et de path. gén., 1928, xxvi, 247. Google Scholar19. CHURCHILL ED: The mechanism of death in massive pulmonary embolism, Surg., Gynec. and Obst., 1934, lix, 513. Google Scholar20. WOODWOLFERTH FCCC: Experimental coronary occlusion, Arch. Int. Med., 1933, li, 771. CrossrefGoogle Scholar21. HARRISHUSSEY BRR: The electrocardiographic changes following coronary artery ligation in dogs, Am. Heart Jr., 1936, xii, 724. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Baltimore, Maryland*Received for publication February 23, 1938.From the Department of Medicine, University of Maryland.†Hitchcock Fellow in Medicine, School of Medicine, University of Maryland.‡Deceased. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byComparison between Negative T waves characteristics in acute coronary syndrome and pulmonary embolismThe electrocardiogramA Case of Acute Pulmonary Embolism with Chest Pain and ST Depression Improved by NitroglycerinElectrocardiography may be a useful tool in the diagnosis of early mild canine heartworm diseaseGiant Inverted T waves in the emergency department: case report and review of differential diagnosesDiseases of the Heart and LungsRelationship Between ECG Findings and Pulmonary Artery Pressure in Patients With Acute Massive Pulmonary Thromboembolism.Major Pulmonary EmbolismSerial changes in negative T wave on electrocardiogram in acute pulmonary thromboembolismThe ECG in Pulmonary EmbolismValue of the 12-lead electrocardiogram at hospital admission in the diagnosis of pulmonary embolismUnusual electrocardiographic response during pulmonary balloon valvoplastyThe electrocardiogram in acute pulmonary embolismThe effect of acute pulmonary artery obstruction on the dog electrocardiogramECG changes in experimental acute pulmonary hypertension with and without hypoxiaRelation of the electrocardiogram to hemodynamic alterations in pulmonary embolismPULMONARY EMBOLISMPathophysiologie der HerzinsuffizienzThe vectorcardiogram in pulmonary embolism. IISystolic and diastolic loading of the heart. ISystolic and diastolic loading of the heart. IIThe electrocardiographic diagnosis of acute cor pulmonaleSymptomatik Und Pathogenese Des Akuten HerzversagensElectropathology of acute cor pulmonaleElectrocardiographic changes in pulmonary embolism with special reference to an early and transient shift of the electrical axis of the heartThromboembolismAcute coronary insufficiency due to pulmonary embolismPulmonary Embolism: A Precipitating Factor of Acute Coronary InsufficiencyAn experimental study of acute pulmonary arterial obstruction, with special reference to the precordial electrocardiogramIs there a vagal pulmonocoronary reflex in pulmonary embolism?Pulmonary EmbolismThe Use of Electrocardiograms in MedicinePulmonary embolism with and without acute cor pulmonale, with especial reference to the electrocardiogramThe Electrocardiogram after PneumonectomyThe electrocardiogram in pulmonary embolism 1 June 1938Volume 11, Issue 12Page: 2109-2123KeywordsElectrocardiographyPulmonary embolism ePublished: 1 December 2008 Issue Published: 1 June 1938 PDF downloadLoading ...