CARBON TETRACHLORIDE POISONING; A REPORT OF ONE CASE WITH NECROPSY AND ONE NONFATAL CASE WITH CLINICAL LABORATORY STUDIES
Authors: William B. Martin, Louis H. Dyke, Fred L. Coddington, Albert M. Snell
Journal: Annals of Internal Medicine (1946)

Article1 September 1946CARBON TETRACHLORIDE POISONING; A REPORT OF ONE CASE WITH NECROPSY AND ONE NONFATAL CASE WITH CLINICAL LABORATORY STUDIESWILLIAM B. MARTIN, LOUIS H. DYKE JR., FRED L. CODDINGTON, ALBERT M. SNELLWILLIAM B. MARTINSearch for more papers by this author, LOUIS H. DYKE JR.Search for more papers by this author, FRED L. CODDINGTONSearch for more papers by this author, ALBERT M. SNELLSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-25-3-488 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTwo recent cases in which the patients were admitted to the United States Naval Hospital, Oakland, California, and in one of which the termination was fatal, attest to the medical importance of carbon tetrachloride intoxication. As will be mentioned later in the reports of cases, both men, by ignoring simple precautions in the matter of ventilation, exposed themselves to toxic quantities of the volatilized chemical. That physicians generally are not sufficiently aware of the dangers of exposure to carbon tetrachloride is evidenced by the failure to establish a correct diagnosis prior to entry in this hospital in either case, despite...Bibliography1. HAMILTON A: Industrial toxicology, 1934, Harper & Brothers Publishers, New York, 329 pp. Google Scholar2. SMETANA H: Nephrosis due to carbon tetrachloride, Arch. Int. Med., 1939, lxiii, 760-777. CrossrefGoogle Scholar3. QUADLAND HP: Carbon tetrachloride: Part 2 of a literature study of reports of occupational injuries attributed to volatile solvents, Indust. Med., 1943, xii, 821-828. Google Scholar4. ALLISON BR: The treatment of acute carbon tetrachloride poisoning; with a report of two cases, Ann. Int. Med., 1942, xvi, 81-93. Google Scholar5. SANFORD SP: Carbon tetrachloride poisoning, U. S. Nav. Med. Bull., 1943, xli, 1486-1488. Google Scholar6. KONWALERNOYES BECB: Carbon tetrachloride poisoning; report of cases, California and West. Med., 1944, lxi, 16-20. Google Scholar7. SHERMANBINDER SRCF: Hazards of carbon tetrachloride in present-day use, U. S. Nav. Med. Bull., 1944, xliii, 590-599. Google Scholar8. FORBES JR: Carbon tetrachloride nephrosis, Lancet, 1944, ii, 590-592. CrossrefGoogle Scholar9. WILLCUTTS MD: Quoted by Konwaler, B. E. and Noyes, C. B.6 Google Scholar10. DILLENBERGTHOMPSON SMCM: Carbon tetrachloride poisoning; a report of twenty cases with one death, Mil. Surg., 1945, xcvii, 39-44. Google Scholar11. EDDY JH: Carbon tetrachloride poisoning; a preliminary report on the use of methionine in hepatitis, Jr. Am. Med. Assoc., 1945, cxxviii, 994-996. CrossrefGoogle Scholar12. SMYTHSMYTH HFHF: Safe practices in the industrial use of carbon tetrachloride, Jr. Am. Med. Assoc., 1936, cvii, 1683-1687. CrossrefGoogle Scholar13. STEWARTWITTS ALJ: Quoted in: Carbon tetrachloride poisoning, Lancet, 1944, i, 570-571. Google Scholar14. BOWDITCH M: Pros and cons of standardization in setting threshold limits, Indust. Med., 1944, xiii, 728. Google Scholar15. ROBBINS RH: The absorption, distribution and excretion of carbon tetrachloride in dogs under various conditions, Jr. Pharmacol. and Exper. Therap., 1929, xxxvii, 203-216. Google Scholar16. CORCORANTAYLORPAGE ACRDIH: Acute toxic nephrosis; a clinical and laboratory study based on a case of carbon tetrachloride poisoning, Jr. Am. Med. Assoc., 1943, cxxiii, 81-85. CrossrefGoogle Scholar17. SIMON MA: Acute toxic nephritis due to inhalation of carbon tetrachloride fumes, Canad. Med. Assoc. Jr., 1939, xli, 580-583. Google Scholar18. WOOD D: Personal communication to the authors. Google Scholar19. WIRTSCHAFTER ZT: Quoted by Eddy, J. H., Jr.11 Google Scholar20. MINOTCUTLER ASJT: Guanidine retention and calcium reserve as antagonistic factors in carbon tetrachloride and chloroform poisoning, Jr. Clin. Invest., 1928, vi, 369-400. CrossrefGoogle Scholar21. HAGENALEXANDERPEPPARD WSHATA: Toxic effects of carbon tetrachloride; report of case, Minnesota Med., 1940, xxiii, 715-718. Google Scholar22. MADDINGBUTT GFHR: Hepatitis resulting from inhalation of carbon tetrachloride, Proc. Staff Meet., Mayo Clin., 1938, xiii, 391-394. Google Scholar23. BEATTIEHERBERTWECHTELSTEELE JPHCCW: Studies on hepatic dysfunction. I. Carbon tetrachloride poisoning treated with casein digest and methionine, Brit. Med. Jr., 1944, i, 209-211. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication December 4, 1945.This article has been released for publication by the Division of Publications of the Bureau of Medicine and Surgery of the United States Navy. The opinions and views set forth in this article are those of the writers and are not to be considered as reflecting the policies of the Navy Department. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byEin Fall von tödlicher oraler TetrachlorkohlenstoffvergiftungAcute Renal Insufficiency Due to Lower-Nephron NephrosisToxic Effects of Gases and VaporsRenal Injury Following Exposure to Carbon Tetrachloride 1 September 1946Volume 25, Issue 3Page: 488-497KeywordsClinical laboratoriesIntoxicationResearch laboratoriesSurgeryTetrachloride ePublished: 1 December 2008 Issue Published: 1 September 1946 PDF downloadLoading ...