Sinusitis and Gastroesophageal Reflux Disease
Authors: John K. DiBaise
Journal: Annals of Internal Medicine (1998)

Letters15 December 1998Sinusitis and Gastroesophageal Reflux DiseaseJohn K. DiBaise, MD, James V. Huerter, MD, and Eamonn M.M. Quigley, MDJohn K. DiBaise, MDUniversity of Nebraska Medical Center; Omaha, NE 68198-2000, James V. Huerter, MDUniversity of Nebraska Medical Center; Omaha, NE 68198-2000, and Eamonn M.M. Quigley, MDUniversity of Nebraska Medical Center; Omaha, NE 68198-2000Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-129-12-199812150-00029 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Chronic sinusitis that is refractory to medical and surgical therapy presents a considerable clinical challenge. An association between gastroesophageal reflux disease (GERD) and chronic sinusitis has been suggested [1-3]. We reviewed the clinical presentation, diagnostic evaluation, and treatment of patients with chronic refractory sinusitis referred for evaluation of GERD.Nineteen patients (11 women; mean age, 50.2 years [range, 16 to 76 years]) were evaluated (Table 1). Eighteen had previously undergone sinus surgery. Thirteen (68%) described classic GERD symptoms, and 14 (74%) had possible "atypical" GERD symptoms. On endoscopy (n = 8), 1 patient had erosive esophagitis and ...References1. Contencin P, Narcy P. Nasopharyngeal pH monitoring in infants and children with chronic rhinopharyngitis. Int J Pediatr Otorhinolaryngol. 1991; 22:249-56. Google Scholar2. Chambers DW, Davis WE, Cook PR, Nishioka GJ, Rudman DT. Long-term outcome analysis of functional endoscopic sinus surgery: correlation of symptoms with endoscopic examination findings and potential prognostic variables. Laryngoscope. 1997; 107:504-10. Google Scholar3. El-Serag HB, Sonnenberg A. Comorbid occurrence of laryngeal and pulmonary disease with esophagitis in United States military veterans. Gastroenterology. 1997; 113:755-60. Google Scholar4. DiBaise JK, Lof J, Park FL, Quigley EM. 24-hour dual-channel esophageal pH-metry in healthy individuals using a fixed-interval catheter: intrinsic variability; effects of gender and meals [Abstract]. Am J Gastroenterol. 1997; 92:1589A. 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