MANAGEMENT OF INTRACTABLE SPRUE WITH CORTISONE AND ADRENOCORTICOTROPIN (ACTH)
Authors: H COLCHER, S R DRACHMAN, D ADLERSBERG
Journal: Annals of Internal Medicine (1953)

Article1 March 1953MANAGEMENT OF INTRACTABLE SPRUE WITH CORTISONE AND ADRENOCORTICOTROPIN (ACTH)HENRY COLCHER, M.D., STANLEY R. DRACHMAN, M.D., DAVID ADLERSBERG, M.D., F.A.C.P.HENRY COLCHER, M.D.Search for more papers by this author, STANLEY R. DRACHMAN, M.D.Search for more papers by this author, DAVID ADLERSBERG, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-38-3-554 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn a previous communication,1a observations on the clinical and chemical effects of cortisone and ACTH in the sprue syndrome were reported. Independently, similar observations by other authors1b, 1c have been published. Of the five patients with primary sprue studied by us, four proved to be resistant to the conventional forms of therapy prior to the use of these hormones.1a It is the purpose of this paper to report the results of prolonged treatment and certain additional observations made in the past 18 months. The group studied consisted of the above five patients and three others.CLINICAL CHARACTERISTICSThe eight patients...Bibliography1. AdlersbergColcherDrachman DHSR(a) : Studies on the effects of cortisone and pituitary adrenocorticotropic hormone (ACTH) in the sprue syndrome, Gastroenterology 19: 674, 1951. (b) Almy, T. P.: A refractory case of idiopathic steatorrhea (non-tropical sprue), with observations on the therapeutic effects of salt-poor human albumin and of adrenocorticotropic hormone, Ann. Int. Med. 34: 1041, 1951. (c) Taylor, A. B., Comfort, M. W., Wollaeger, E. E., and Power, M. H.: The effect of cortisone in non-tropical sprue, J. Clin. Investigation 30: 678, 1951 (abstract). CrossrefMedlineGoogle Scholar2. AdlersbergSchein DJ: Clinical and pathological studies in sprue, J. A. M. A. 134: 1459, 1947. CrossrefMedlineGoogle Scholar3. AdlersbergRabinowitz DD: The sprue syndrome—improved dietary management, J. Am. Dietet. A. 26: 879, 1950. CrossrefMedlineGoogle Scholar4. VerzarLaszt FL: Nebennierenrinde und Fettresorption, Biochem. Ztschr. 278: 396, 1935. Google Scholar5. VerzarMacDougall FEJ: Absorption from the intestine, 1936, Longmans, London. Google Scholar6. Marazzi R: The influence of adrenalectomy and of fasting on the intestinal absorption of carbohydrates, Am. J. Physiol. 131: 36, 1940. CrossrefGoogle Scholar7. BarnesWickMillerMacKay RHANESEM: Effect of adrenalectomy on rate of fat absorption, Proc. Soc. Exper. Biol. and Med. 40: 651, 1939. CrossrefGoogle Scholar8. StilmanEntenmanAndersonChaikoff NCEIL: Phosphorylation of fat in absence of adrenal glands as measured with radioactive phosphorus, Endocrinology 31: 481, 1942. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Received for publication August 5, 1952.From the Medical Services, Nutrition Clinic, and the Division of Chemistry, The Mount Sinai Hospital.†Sara Welt Fellow in Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byIntestinal absorption of calcium and phosphorus: Experiments on interaction between vitamin D and adrenocortical hormoneThe possible role of dietary factors in the aetiology and pathogenesis of sprue, coeliac disease and idiopathic steatorrhoeaPathogenetic Concepts of the Malabsorption SyndromeRadioactive Fat Absorption and Clinical Response of Sprue to Steroid TherapyTHE XYLOSE TOLERANCE TEST AS A MEASURE OF THE INTESTINAL ABSORPTION OF CARBOHYDRATE IN SPRUE*†J. M. FINLAY, M.D., F.R.C.P.(C), K. J. R. WIGHTMAN, M.D., F.R.C.P.(C), F.A.C.P.Management of patients with massive resection of the small intestine with special reference to the use of steroid hormonesLong-term or maintenance adrenal steroid therapy in non-tropical sprueVITAMIN D INTOXICATION: REPORT OF TWO CASES TREATED WITH CORTISONE*JOHN V. VERNER JR., M.D., FRANK L. ENGEL, M.D., HARRY T. MCPHERSON, M.D.THE SYNDROME OF HYPOPARATHYROIDISM, ADDISION'S DISEASE AND MONILIASISThe Use of ACTH and Adrenocorticosteroids in Diseases of the Digestive SystemAdrenal Steroids in the Treatment of the Malabsorption SyndromeGastrointestinal malabsorptive syndromesPreviously Undescribed Clinical and Postmortem Observations in Non-Tropical Sprue: Possible Role of Prolonged Corticosteroid TherapyGastrointestinal wheat allergyMODERN TREATMENT OF THE MALABSORPTION SYNDROME IN ADULTS*JOHN M. FINLAY, M.D., F.R.C.P.(C), KEITH J. R. WIGHTMAN, M.D., F.R.C.P.(C), F.A.C.P.Intestinal Lipodystrophy (Whipple's Disease) Amenable to Corticosteroid TherapyPROLONGED DIARRHEA WITH NEAR-FATAL HEMORRHAGE DUE TO HYPOPROTHROMBINEMIA*WILLIAM B. SCHARFMAN, M.D., SIMON PROPP, M.D., F.A.C.P.The Treatment of Primary and Secondary SyphilisThe Treatment of SteatorrhoeaChronic and recurrent diarrheaEffect of ACTH and Cortisone on Fat Absorption in Steatorrhea of Various CausesCorrection of the Anemia of Malabsorption Syndrome (Nontropical Sprue?) by Oral Administration of Cortisone and IronCholeretic Action of CortisoneWhipple's intestinal lipodystrophyHYDROCORTISONE IN THE TREATMENT OF SPRUEWHEELS WITHIN WHEELSMalabsorption syndromeVolvulus of the Colon: A Complication of Sprue 1 March 1953Volume 38, Issue 3Page: 554-567KeywordsAdrenocorticotropic hormoneMedical servicesNutrition ePublished: 1 December 2008 Issue Published: 1 March 1953 PDF downloadLoading ...