"SURGICAL SHOCK" FACTORS IN PNEUMONIA
Authors: Edmund Andrews, Henry N. Harkins
Journal: Annals of Internal Medicine (1937)

Article1 April 1937"SURGICAL SHOCK" FACTORS IN PNEUMONIAEDMUND ANDREWS, M.D., HENRY N. HARKINS, M.D., Ph.D.EDMUND ANDREWS, M.D.Search for more papers by this author, HENRY N. HARKINS, M.D., Ph.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-10-10-1503 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptUnderhill and his associates1, 2, 3did experiments at the time of the World War on the effects of the gases chlorine, phosgene and chlorpicrin. He showed that these lung irritants caused massive pulmonary edema with marked blood concentration. The total extent of this edema was not measured, but it was shown to be a protein-containing exudate. The average increase in blood concentration of four dogs which inhaled 41 to 50 parts per million of phosgene for one-half hour was 166 per cent of the control value as measured by hemoglobin readings. Underhill4showed that in the influenzal pneumonia that...References1. UNDERHILL FP: The lethal war gases, physiology and experimental treatment, 1920, Yale University Press, New Haven. Google Scholar2. UNDERHILL FP: The physiology and experimental treatment of poisoning with the lethal war gases, Harvey Lectures, 1918-1919, pp. 234-255, J. B. Lippincott Company, Philadelphia and London. Google Scholar3. UNDERHILL FP: The physiology and experimental treatment of poisoning with the lethal war gases, Arch. Int. Med., 1919, xxiii, 753-770. CrossrefGoogle Scholar4. UNDERHILLRINGER FPM: Blood concentration changes in influenza: with suggestions for treatment, Jr. Am. Med. Assoc., 1920, lxxv, 1531-1534. Google Scholar5. MOON VH: The shock syndrome in medicine and surgery, ANN. INT. MED., 1935, viii, 1633-1648. Google Scholar6. MOONCRAWFORD VHBL: Shock syndrome in mercuric chloride poisoning, Arch. Path., 1933, xv, 509-515. Google Scholar7. MOONMORGAN VHDR: Experimental pulmonary edema, Proc. Soc. Exper. Biol. and Med., 1936, xxxiii, 560-562. CrossrefGoogle Scholar8. SUNDERMAN FW: Studies of serum electrolytes. VII. The total base and protein components of the serum during lobar pneumonia with a note on the gastric secretion, Jr. Clin. Invest., 1931, ix, 615-633. CrossrefGoogle Scholar9. MOONCRAWFORD VHBL: Shock syndrome in mercuric chloride poisoning, Arch. Path., 1933, xv, 509-515. Google Scholar10. BLALOCK A: Experimental shock. VIII. The importance of the local loss of fluid in the production of the low blood pressure after burns, Arch. Surg., 1931, xxii, 610-616. CrossrefGoogle Scholar11. HARKINS HN: Experimental burns. I. The rate of fluid shift and its relation to the onset of shock in severe burns, Arch. Surg., 1935, xxxi, 71-85. CrossrefGoogle Scholar12. HARKINS HN: Shock due to freezing: I. Shift of body fluids and associated blood concentration changes, Proc. Soc. Exper. Biol. and Med., 1934, xxxii, 432-434; HARKINS, H. N., and HUDSON, J. E.: Shock due to freezing: II. Composition of edema fluid, ibid., 434-435; HARKINS, H. N., and HARMON, P. H.: Experimental freezing: bleeding volume, general and local temperature changes, ibid., 1935, 1142-1143. CrossrefGoogle Scholar13. WILSONROOME HNW: The effects of constriction and release of an extremity: an experimental study of the tourniquet, Arch. Surg., 1936, xxxii, 334-345. CrossrefGoogle Scholar14. HARKINSHARMONHUDSON HNPHJE: Lethal factors in bile peritonitis. I. Surgical shock, Arch. Surg., 1936, xxxiii, 576-608. CrossrefGoogle Scholar15. BEARDBLALOCK JWA: Experimental shock. VIII. The composition of the fluid that escapes from the blood stream after mild trauma to an extremity, after trauma to the intestines and after burns, Arch. Surg., 1931, xxii, 617-625. CrossrefGoogle Scholar16. JOHNSONBLALOCK GSA: Experimental shock. IX. A study of the effects of the loss of whole blood, of blood plasma and of red blood cells, Arch. Surg., 1931, xxii, 626-637. CrossrefGoogle Scholar17. HARKINSHARMON HNPH: Blood concentration produced by plasmapheresis, Surgery, 1937, i, 276-281. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Chicago, Illinois*Received for publication January 13, 1937.From the Department of Surgery, University of Chicago. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe haemodynamics of human septic shock*Schock und Kollaps 1 April 1937Volume 10, Issue 10Page: 1503-1507KeywordsAttentionBloodEdemaHemoglobinLungsPneumoniaProteinsShockSurgery ePublished: 1 December 2008 Issue Published: 1 April 1937 PDF downloadLoading ...