AN EVALUATION OF THE SERUM IRON IN LIVER DISEASE
Authors: C M STONE, J M RUMBALL, C P HASSETT
Journal: Annals of Internal Medicine (1955)

Article1 August 1955AN EVALUATION OF THE SERUM IRON IN LIVER DISEASECHAUNCEY M. STONE JR., M.D., JOHN M. RUMBALL, M.D., F.A.C.P., CLAIRE P. HASSETT, A.B.CHAUNCEY M. STONE JR., M.D.Search for more papers by this author, JOHN M. RUMBALL, M.D., F.A.C.P.Search for more papers by this author, CLAIRE P. HASSETT, A.B.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-43-2-229 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe internal redistribution of iron in the body occurs through the serum iron compartment, with the liver playing an important rôle. Yet determinations of serum iron levels in liver diseases were few in the English literature until 1949. The foreign journals, however, contained observations of serum iron changes in liver diseases, which were first reported in 1927 by Warburg and Krebs.1 This foreign literature was recently reviewed by Ducci, Spoerer and Katz,2 who found that most foreign investigators considered the serum iron levels of value in the differential diagnosis of jaundice.In this country Moore, Doan and Arrowsmith3in 1937,...Bibliography1. WarburgKrebs OHA: Über locker gebundenes Kupfer und Eisen im Blutserum, Biochem. Ztschr. 190: 143, 1927. Google Scholar2. DucciSpoererKatz HAR: Serum iron in liver disease, Gastroenterology 22: 52, 1952. CrossrefMedlineGoogle Scholar3. MooreDoanArrowsmith CVCAWR: Studies in iron transportation and metabolism. II. The mechanism of iron transportation: its significance in iron utilization in anemic states of varied etiology, J. Clin. Investigation 16: 627, 1937. CrossrefMedlineGoogle Scholar4. RathFinch CECA: Chemical, clinical and immunological studies on the products of human plasma fractionation. XXXVIII. Serum iron transport. Measurement of serum iron-binding capacity in man, J. Clin. Investigation 28: 79, 1949. CrossrefGoogle Scholar5. Howard RB: Iron metabolism in liver disease, Bull. University of Minnesota Hosp. 21: 133, 1949. Google Scholar6. MatassarinDelp BMMH: The relation of serum iron to hepatocellular damage, Am. J. M. Sc. 224: 622, 1952. CrossrefMedlineGoogle Scholar7. Peterson RE: The serum iron in acute hepatitis, J. Lab. and Clin. Med. 39: 225, 1952. MedlineGoogle Scholar8. Christian ER: Behavior of serum iron in various diseases of liver, Arch. Int. Med. 94: 22, 1954. CrossrefGoogle Scholar9. BarkinWalker GBS: Determination of serum iron and pseudohemoglobin iron with o-phenanthrolin, J. Biol. Chem. 135: 37, 1940. CrossrefGoogle Scholar10. SmetanaKellerDubin HFTCIN: Histologic criteria for the differential diagnosis of liver diseases in needle biopsies, Rev. Gastroenterol. 20: 227, 1953. MedlineGoogle Scholar11. ReissmanBoleyChristiansonDelp KRJJFMH: The serum iron in experimental hepatocellular necrosis, J. Lab. and Clin. Med. 43: 572, 1954. MedlineGoogle Scholar12. WeisbrodSchiffGallClevelandBerman FGLEAFPJR: Symposium on liver disease, needle biopsy of the liver, experiences in differential diagnosis of jaundice, Gastroenterology 14: 56-72 (Jan.) 1950. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Coral Gables, Florida*Received for publication December 15, 1954.From the Medical Service, Veterans Administration Hospital, Coral Gables, Florida. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byIron absorption in infectious hepatitisNeuroleptanalgesia und LeberfunktionIron absorption in acute hepatitisDevelopment of hemochromatosis in a patient with Laennec's cirrhosisSerum Glutamic Oxalacetic Transaminase and Iron in the Differential Diagnosis of JaundiceLiver Function Tests-Their Clinical SignificanceThe Behavior of Serum Iron in Acute HepatitisSerum Transaminase and Serum Iron in Liver DiseaseSerum iron and gastric acidity in gastric carcinoma, peptic ulcer, and other diseasesIron Deficiency Following Subtotal Gastric ResectionNachträge 1 August 1955Volume 43, Issue 2Page: 229-240KeywordsCirrhosisHepatitisLiverLiver diseasesMedical servicesNecrosis ePublished: 1 December 2008 Issue Published: 1 August 1955 Copyright & PermissionsCopyright, 1955, by The American College of PhysiciansPDF downloadLoading ...