THE SYSTOLIC MURMUR: FURTHER OBSERVATIONS ON ITS CLINICAL SIGNIFICANCE
Authors: Richard D. Friedlander, Morton G. Brown
Journal: Annals of Internal Medicine (1935)

Article1 February 1935THE SYSTOLIC MURMUR: FURTHER OBSERVATIONS ON ITS CLINICAL SIGNIFICANCERICHARD D. FRIEDLANDER, M.D., MORTON G. BROWN, M.D.RICHARD D. FRIEDLANDER, M.D.Search for more papers by this author, MORTON G. BROWN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-8-8-893 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe clinical significance and the circulatory dynamic background of systolic murmurs have been subjects of considerable discussion for a great many years and probably will remain so.1, 2, 3, 4The interpretations of such murmurs have varied from time to time. Once they were generally recognized as indicative of grave heart disease and later as having no meaning whatever.5More recently a middle course has been taken by many of those interested in the subject.1, 6The phenomenon is such that careful clinical observation in human beings offers the means of clarifying some of the confusion that exists. For this...Bibliography1. FREEMANLEVINE ARSA: Clinical significance of systolic murmur; study of 1,000 consecutive "non-cardiac" cases, ANN. INT. MED., 1933, vi, 1371-1385. LinkGoogle Scholar2. KAHLER H: Über das Verhalten der Herzgeräusche bei Einwirkung von Amylnitrit (Ein Beitrag zur Differentialdiagnose und Genese der Herzgeräusche), Wien. Arch. f. inn. Med., 1933, xxiii, 349-372. Google Scholar3. SIEMSEN WJ: Evaluation of non-organic auscultatory cardiac findings and venous hum in children, Am. Jr. Dis. Child., 1934, xlvii, 1100-1109. Google Scholar4. FAHR G: Significance of systolic murmur, Nebr. Med. Jr., 1930, xv, 458-463. Google Scholar5. CABOT RC: Facts on the heart, 1926, W. B. Saunders Company, Philadelphia. Google Scholar6. LEVINE SA: Systolic murmur; its clinical significance, Jr. Am. Med. Assoc., 1933, ci, 436-438. CrossrefGoogle Scholar7. NORRISLANDIS GWHR: Diseases of the chest and the principles of physical diagnosis, 1926, W. B. Saunders Company, Philadelphia. Google Scholar8. MORISON RA: The value of amyl nitrite inhalations in the diagnosis of mitral stenosis, Brit. Med. Jr., 1918, i, 452-453. CrossrefGoogle Scholar9. COTTONSLADELEWIS IFJGT: Observations upon amyl nitrite, Heart, 1917, vi, 311-315. Google Scholar10. BLUMGART HL: Velocity of blood flow in health and disease; velocity of blood flow in man and its relation to other measurements of circulation, Medicine, 1931, x, 1-75. CrossrefGoogle Scholar11. GROLLMAN A: The cardiac output of man in health and disease, 1932, Charles C. Thomas, Springfield, Illinois. Google Scholar12. LOVEMCGUIGANWILEY GRHCE: The action of nitrites upon pulmonary circulation, Jr. Lab. and Clin. Med., 1925, x, 885-891. Google Scholar13. THAYER WS: Interpretation of systolic cardiac murmurs, Am. Jr. Med. Sci., 1925, clxix, 313-321. Google Scholar14. GORDONWELLS BG: Effect of amyl nitrite, bleeding and epinephrin on blood pressure and size of cat's heart, Arch. Int. Med., 1924, xxxiii, 738-741. CrossrefGoogle Scholar15. BRAMSSTRAUSS WAHA: Effect of amyl nitrite on size of heart and width of aortic shadow as determined roentgenologically, Am. Jr. Med. Sci., 1930, clxxx, 618-620. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication July 16, 1934.From the Medical Clinic of the Peter Bent Brigham Hospital.This work was aided in part by a grant from the Proctor Fund of the Harvard Medical School. Nextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byMurmur grading in humans and animals: past and presentIncidence of Murmurs in the Aging HeartBibliographyThe late systolic murmurFunctional Tests as an Aid to Cardiac AuscultationTHE USE OF AMYL NITRITE IN THE DIAGNOSIS OF SYSTOLIC MURMURSTHE AORTIC SYSTOLIC MURMUR DEVELOPING WITH INCREASING AGETHE USE OF AMYL NITRITE IN DIFFERENTIATING MITRAL AND AORTIC SYSTOLIC MURMURSThe sounds produced by the friction of normal serosaeThe significance of and a differential diagnostic test of precordial murmurs in children 1 February 1935Volume 8, Issue 8Page: 893-899KeywordsCardiovascular therapyHospitalsSystolic ejection murmur ePublished: 1 December 2008 Issue Published: 1 February 1935 PDF downloadLoading ...