PERMANENT CONTROL OF NOSEBLEEDS IN PATIENTS WITH HEREDITARY HEMORRHAGIC TELANGIECTASIA
Authors: W H SAUNDERS
Journal: Annals of Internal Medicine (1960)

Article1 July 1960PERMANENT CONTROL OF NOSEBLEEDS IN PATIENTS WITH HEREDITARY HEMORRHAGIC TELANGIECTASIAWILLIAM H. SAUNDERS, M.D.WILLIAM H. SAUNDERS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-53-1-147 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptRecurrent familial epistaxis was first recognized by Babbington1 in 1865. He reported "hereditary epistaxis" in five generations of a family. Legg in 18762 confused the disorder with hemophilia, as did Chiari in 18873 and Chauffard in 1896.4 Rendu5 distinguished it from hemophilia in 1896. Meanwhile Osler,6 at The Johns Hopkins Hospital, had been observing three patients with the disorder, and in 1901 published his classic description, "On a Family Form of Recurring Epistaxis with Multiple Telangiectases of the Skin and Mucous Membranes."After Osler's account, Kelly in 19067presented excellent color drawings of patients with multiple telangiectases. Weber9described a...Bibliography1. Babbington BG: Hereditary epistaxis, Lancet 2: 362, 1865. Google Scholar2. Legg W: A case of hemophilia complicated with multiple naevi, Lancet 2: 856, 1876. Google Scholar3. Chiari O: Erfahrungen auf dem Gebiete der Hals und Nasenkrankheiten, 1887, Toeplitz & Deuticke, Vienna, pp. 60 et seq. Google Scholar4. Chauffard MA: Hemophilie avec stigmates telangiectasiqucs, Bull, et mém. Soc méd. d. hôp. de Paris 13: 352-358, 1896. Google Scholar5. Rendu : Epistaxis répéteés chez sujet porteur de petits angiomes cutanes et muqueuex, Gaz. d. hôp. 69: 1322, 1896. Google Scholar6. Osler W: On a family form of recurring epistaxis with multiple telangiectases of the skin and mucous membranes, Bull. Johns Hopkins Hosp. 12: 333 (Nov.) 1901. Google Scholar7. Kelly AB: Multiple telangiectases of the skin and mucous membranes of the nose and mouth, Glasgow M. J. 65: 411-422 (June) 1906. MedlineGoogle Scholar8. Osler W: On multiple hereditary telangiectases with recurring hemorrhages, Quart. J. Med. 1: 53-58 (Oct.) 1907, plate II. Google Scholar9. Weber FP: Multiple hereditary developmental angioma ta (telangiectases) of the skin and mucous membranes associated with recurring hemorrhages, Lancet 2: 160-162 (July 20) 1907. Google Scholar10. Hanes FM: Multiple hereditary telangiectases causing hemorrhage (hereditary hemorrhagic telangiectasia), Bull. Johns Hopkins Hosp. 20: 63, 1909. Google Scholar11. SnyderDoan LHCA: Is the homozygous form of multiple telangiectasia lethal?, J. Lab. and Clin. Med. 29: 1211, 1944. Google Scholar12. Weber FP: Letter to the editor, Brit M. J. 1: 569, 1954. CrossrefMedlineGoogle Scholar13. LivingstonCarr SORE: Hereditary hemorrhagic telangiectasia, report of a case with hemothorax, J. Thoracic Surg. 31: 497, 1956. CrossrefGoogle Scholar14. Saunders WH: Septal dermoplasty for control of nosebleeds caused by hereditary hemorrhagic telangiectasia or septal perforations, Tr. Am. Acad. Ophth. and Otolaryng., to be published. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Columbus, Ohio*Received for publication December 4, 1959.From the Department of Otolaryngology, The Ohio State University, Columbus, Ohio.Requests for reprints should be addressed to William H. Saunders, M.D., Department of Otolaryngology, The Ohio State University, Columbus 10, Ohio. 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ROSEN, M.D., DAVID K. SIROTA, M.D., STANLEY C. MARINOFF, M.D.Outcome of Pregnancy in Patients with Hereditary Hemorrhagic TelangiectasiaStörungen der GefäßfunktionExcision of nasal lining and split-skin graft replacement in Osler's diseaseMedical genetics 1960 1 July 1960Volume 53, Issue 1Page: 147-152KeywordsHemophiliaHemophilia AHemorrhageMucous membranes Issue Published: 1 July 1960 PDF DownloadLoading ...