HEREDITARY HEMORRHAGIC TELANGIECTASES ASSOCIATED WITH PULMONARY ARTERIOVENOUS FISTULA IN TWO MEMBERS OF A FAMILY
Authors: John H. Moyer, Alfred J. Ackerman
Journal: Annals of Internal Medicine (1948)

Article1 November 1948HEREDITARY HEMORRHAGIC TELANGIECTASES ASSOCIATED WITH PULMONARY ARTERIOVENOUS FISTULA IN TWO MEMBERS OF A FAMILYJOHN H. MOYER, ALFRED J. ACKERMANJOHN H. MOYER, ALFRED J. ACKERMANAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-29-5-775 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlthough it is generally known that hereditary hemorrhagic telangiectases frequently involve visceral organs, the "cavernous hemangioma" of the lung is so rarely thought of that it usually remains unrecognized, even in the presence of mucocutaneous telangiectases. The clinical symptoms and signs which form the classical manifestations of this disorder are not infrequently attributed to congenital heart disease. Pulmonary opacities demonstrated radiologically have been usually misinterpreted, though they may be sufficiently characteristic to permit a correct early diagnosis.In this presentation it is our intention to discuss the clinicopathological and radiologic manifestations of pulmonary arteriovenous fistulae observed in two members of...Bibliography1. ADAMSTHORNTONEICHELBERGER WETFL: Cavernous hemangioma of the lung, Arch. Surg., 1944, xlix, 51-58. CrossrefGoogle Scholar2. ADAMSON HG: Case of multiple telangiectasia, Proc. Roy. Soc. Med., 1909, ii, 128. CrossrefGoogle Scholar3. BALLANTYNE AJ: Multiple telangiectasia; three cases in one family, Glasgow Med. Jr., 1908, lxx, 256. Google Scholar4. BARCROFTBINGERBOCHDOGGERT JCJAVJH: Trans. Roy. Soc. London, s.B., 1923, ccxi, 351. Google Scholar5. BARROCK JJ: Hereditary hemorrhagic telangiectasia, Wisconsin Med. Jr., 1944, xliii, 805-814. Google Scholar6. BERT P: La pression barometrique, 1878, G. Masson, Paris. Google Scholar7. BOSTON N: Gastric hemorrhage due to familial telangiectasia, Am. Jr. Med. Sci., 1930, clxxx, 798-802. CrossrefGoogle Scholar8. BOWERS WF: Rupture of visceral hemangioma as cause of death with report of case of pulmonary hemangioma, Nebr. Med. Jr., 1936, xxi, 55. Google Scholar9. BUIST NE: Hereditary hemorrhagic telangiectasia, Am. Jr. Med. Sci., 1946, ccxi, 577-582. Google Scholar10. CURSHMANN H: Ueber familiäres Nasenbluten, als Ausdruck einer Pseudohaemophilie, Klin. Wchnschr., 1930, ix, 677. CrossrefGoogle Scholar11. DE LANGEDE VRIESRABLES CSB: Angioma of lung in infant, Ztschr. f. Kinderh., 1923, xxxiv, 304. Google Scholar12. FINGERLANDJANOUSEK AB: Hereditary hemorrhagic telangiectasia (Osler's disease), Arch. Derm. and Syph., 1938, clxxviii, 54-64. CrossrefGoogle Scholar13. FITZ- HUGH T. J. : The importance of atavism in the diagnosis of hereditary hemorrhagic telangiectasia, Am. Jr. Med. Sci., 1923, clxvi, 884. CrossrefGoogle Scholar14. GOLDBLOOMGOTTLIEB ARJ: Icterus neonatorum, oxygen capacity and saturation of fetus and mother, Jr. Clin. Invest., 1930, viii, 375. CrossrefGoogle Scholar15. FOLDMAN A: Cavernous hemangioma of the lung. Secondary polycythemia, Dis. Chest, 1943, ix, 479-486. CrossrefGoogle Scholar16. GOLDSTEIN HI: Hereditary hemorrhagic telangiectasia with recurring hereditary epistaxis with a report 11 cases in one family, Arch. Int. Med., 1921, xxvii, 102. CrossrefGoogle Scholar17. HALL EM: Am. Jr. Path., 1935, xi, 343. Google Scholar18. HEPBURNDAUPHINEE JJA: Successful removal of hemangioma of the lung followed by disappearance of polycythemia, Am. Jr. Med. Sci., 1942, cciv, 681-685. CrossrefGoogle Scholar19. HURTADOMERINODELGADO ACE: Influence of anoxemia on the hemopoietic activity, Arch. Int. Med., 1945, lxxv, 284-323. CrossrefGoogle Scholar20. JANES RM: Multiple cavernous hemangiomas of the lung successfully treated by local resection of the tumors, Brit. Jr. Surg., 1944, xxxi, 270-273. CrossrefGoogle Scholar21. JONESTHOMPSON JCWP: Arteriovenous fistula of the lung, Jr. Thorac. Surg., 1944, xiii, 357-373. CrossrefGoogle Scholar22. KENNEDYBURWELL AC: Measurement of the circulation in a patient with multiple AV connections, Am. Heart Jr., 1944, xxviii, 133. CrossrefGoogle Scholar23. LARRABEELITTMAN RCD: Hereditary hemorrhagic telangiectasis, N. Eng. Jr. Med., 1932, ccvii, 1177. CrossrefGoogle Scholar24. LIBMANOTTENBERG ER: Hereditary hemoptysis, Jr. Am. Med. Assoc., 1923, lxxxi, 2030. CrossrefGoogle Scholar25. LINDGREN E: Roentgen diagnosis of arteriovenous aneurysm of the lung, Acta Radiol., 1946, xxvii, 585-600. Google Scholar26. LIPPMAN A: Klin. Wchnschr., 1926, v, 1406. CrossrefGoogle Scholar27. LYSTER TC: Recurrent retinal hemorrhages; report of cases, Calif. and West. Med., 1931, xxxv, 300. Google Scholar28. MADDEN JF: Discussion of T. K. LAWLESS': Telangiectasia (hereditary, hemorrhagic). "Osler's recurring epistaxis with multiple telangiectasia of the skin and mucous membranes," Arch. Derm. and Syph., 1934, xxx, 295. Google Scholar29. MAKLORZION PTD: Multiple pulmonary hemangiomata, Am. Jr. Med. Sci., 1946, ccxi, 261-272. CrossrefGoogle Scholar30. MEIKLE GJ: Hemorrhagic hereditary telangiectasia, Lancet, 1933, ii, 863. CrossrefGoogle Scholar31. MCFARLANDGRAYBIELLILIENCRANTZTUTTLE RAAEAD: An analysis of the physiological and psychological characteristics of 200 civil airline pilots, Jr. Aviation Med., 1939, x, 160. Google Scholar32. NEUMARK : La maladie d'Osler (In Deliberationes Congressus, dermatologorum internationales), 1936, ii, 746. Johann Ambrosius Barth, Leipzig. Google Scholar33. OSLER W: A family form of recurring epistaxis associated with multiple telangiectases of the skin and mucous membranes, Bull. Johns Hopkins Hosp., 1901, xii, 333. Google Scholar34. PARDO-CASTELLOFARINAS VEP: Hereditary multiple telangiectases, Arch. Derm. and Syph., 1936, xxxix, 1025-1034. Google Scholar35. PENNOYER GP: Congenital arteriovenous aneurysms or fistulae, Surg. Clin. N. Am., 1946, 343-348. MedlineGoogle Scholar36. PRINGLE JJ: Discussant of paper sequeira, Proc. Royal Soc. Med., 1913, vi, 129. Google Scholar37. READING B: A case of congenital telangiectasis of the lung complicated by brain abscess, Texas State Jr. Med., 1932, xxviii, 462-464. Google Scholar38. REID MR: Studies on abnormal arteriovenous communications, acquired and congenital, Arch. Surg., 1925, x, 601, 996; xi, 237. CrossrefGoogle Scholar39. RENDU : Epistaxis repetee chez un sujet porteur de petits angiomes cutanes et muqueaux, Bull. et mém. Soc. méd. d. hôp. de Paris, 1896, xiii, 731. Google Scholar40. RHODES CB: Cavernous hemangiomas of the lung with secondary polycythemia, Jr. Am. Med. Assoc., 1938, cx, 1914. CrossrefGoogle Scholar41. ROWNTREEBROWN LGGE: The volume of the blood and plasma in health and disease, 1924, W. B. Saunders Co., Philadelphia. Google Scholar42. RUNDLES WR: Hemorrhagic telangiectasia with pulmonary artery aneurysm, Am. Jr. Med. Sci., 1945, ccx, 76-81. CrossrefGoogle Scholar43. SCHOEN R: Familiäre Telangiectasie mit habituellem Nasenbluten, Deutsch. Arch f. klin. Med., 1939, clxvi, 157. Google Scholar44. SCHUSTER NH: Familial hereditary telangiectasia associated with multiple aneurysms of the splenic artery, Jr. Path. and Bact., 1937, xliv, 29. CrossrefGoogle Scholar45. SINGERWOLFSON KWQ: Hereditary hemorrhagic telangiectasia, N. Eng. Jr. Med., 1944, ccxxx, 637-642. CrossrefGoogle Scholar46. SISSONMURPHYNEWMAN JHGEEV: Multiple congenital arteriovenous aneurysms in the pulmonary circulation, Bull. Johns Hopkins Hosp., 1945, lxxvi, 93-111. Google Scholar47. SMITHHORTON HLBT: Fistula of lung associated with polycythemia vera, Am. Heart Jr., 1939, xviii, 589. CrossrefGoogle Scholar48. SMITHBELTARNOLDCARRIER HPAEHREB: Blood volume changes at high altitudes, Am. Jr. Physiol., 1925, lxxi, 393. Google Scholar49. STOCK MF: Hereditary hemorrhagic telangiectasis, Arch. Otolaryng., 1944, xl, 103-114. Google Scholar50. SYMMERS D: Telangiectatic splenomegaly, Jr. Am. Med. Assoc., 1921, lxxvii, 2019. Google Scholar51. TEAHAN WW: Hereditary hemorrhagic telangiectasis occurring in six generations, Ann. Int. Med., 1939, xiii, 535-543. Google Scholar52. TINNEYHALLGRIFFIN WSBEHZ: The liver and spleen in polycythemia vera, Proc. Staff Meet. Mayo Clin., 1943, xviii, 46. Google Scholar53. ULLMANN K: Angiomatosis: Ist sie eine Blut- oder Gefaesserkrankung? (In Deliver. Congressus, dermatologorum internationalis), 1936, ii, 743, Johann Ambrosius Barth, Leipzig. Google Scholar54. VAN LIERE EJ: Anoxia: its effect on the body, 1942, University of Chicago Press. Google Scholar55. VOYLEERITCHEY GJO: Hereditary hemorrhagic telangiectasia, Ann. Int. Med., 1945, xxii, 738. Google Scholar56. WEBER FP: Hemorrhagic telangiectasia of Osler type, Brit. Jr. Derm. and Syph., 1936, xlviii, 182. Google Scholar57. WOLLSTEIN M: Malignant hemangiomas of the lung with secondary polycythemia, Jr. Am. Med. Assoc., 1938, cx, 1914. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication September 8, 1947.From the Brooke General Hospital, Brooke Army Medical Center, Fort Sam Houston, Texas. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byNeurological manifestations of hereditary hemorrhagic telangiectasia (rendu-osler-weber disease): Report of 2 cases and review of the literatureGutartige Primärtumoren der Bronchien und LungenCerebral Symptoms in Pulmonary Arteriovenous FistulaOsler's Disease With Multiple Large Vessel AneurysmsRöntgendiagnostik der AtemorganeREFERENCESKurzschlußverbindungen des großen und kleinen KreislaufsHereditary hemorrhagic telangiectasiaPulmonary arteriovenous fistulasThe Clinical Significance of Hereditary Hemorrhagic TelangiectasiaCor pulmonaleKrankheiten der GefäßeCor pulmonaleHereditary Hemorrhagic Telangiectasia and Pulmonary Arteriovenous FistulaAngeborenes arteriovenöses PulmonalisaneurysmaAngeborenes arteriovenöses Pulmonalisaneurysma�ber Ablagerung k�rpereigener Stoffe (Amyloidosis, Calcinosis) bei Morbus OslerHEREDITARY HEMORRHAGIC TELANGIECTASIAPULMONARY ARTERIOVENOUS FISTULAS IN SISTERSTreatment of Thrombosis Occurring in Individuals With Hereditary Hemorrhagic TelangiectasisDie Zirkulationsstörungen der LungePulmonary arteriovenous fistulaGenetic factors in the diseases of later lifePulmonary arteriovenous fistulaKongenitale Herz- und GefäßdefekteArteriovenous aneurysm of the lungHEREDITARY HEMORRHAGIC TELANGIECTASIA: A REPORT OF PULMONARY ARTERIOVENOUS FISTULAE IN MOTHER AND SON; MEDICAL (HORMONAL) AND SURGICAL THERAPY OF THIS DISEASE*EDWARD C. HEYDE, M.D.Hereditary hemorrhagic telangiectasiaPulmonary arteriovenous fistulaPULMONARY TELANGIECTASIA: REPORT OF CASE PROVED BY PULMONARY BIOPSYLVII Hereditary Hemorrhagic TelangiectasiaArteriovenous Fistula of the Lung and an Associated Hemangioma of the Vertebra: Case ReportExtracardiac arteriovenous fistulas in the thoraxHEREDITARY HAEMORRHAGIC TELANGIECTASIA: A GENETIC AND BIBLIOGRAPHICAL STUDY.Pulmonary Arteriovenous FistulaThe Straining Procedure as an Aid in the Anatomic Localization of Cardiovascular Murmurs and SoundsArteriovenous Fistulas of the LungsTwo Cases of Vascular Anomalies in the LungTHE ARTERIOVENOUS ANGIOMATOSIS OF THE LUNG WITH HYPOXAEMIA 1 November 1948Volume 29, Issue 5Page: 775-802KeywordsFistulasHemorrhageLungsPharynxPolycythemiaRespiratory systemSigns and symptomsSweatThoraxTrachea ePublished: 1 December 2008 Issue Published: 1 November 1948 PDF downloadLoading ...