FUNDAMENTAL CONCEPTS IN THE DIAGNOSIS OF SPRUE
Authors: R RODRIGUEZ-MOLINA
Journal: Annals of Internal Medicine (1954)

Article1 January 1954FUNDAMENTAL CONCEPTS IN THE DIAGNOSIS OF SPRUERAFAEL RODRIGUEZ-MOLINA, F.A.C.P.RAFAEL RODRIGUEZ-MOLINA, F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-40-1-33 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSprue is a chronic, wasting disease which, in the light of modern medical science, is classified among the deficiency states. Medical literature during the past 20 years has not significantly altered the basic concepts about sprue. Recent observations, however, have contributed materially to a better understanding of the etiologic factors, diagnostic criteria and effective treatment of this interesting syndrome.1, 2, 3, 4In the earlier writings5, 6great importance was ascribed to the differential diagnosis between sprue and addisonian or pernicious anemia of temperate climates. Mainly through the work of Castle, Rhoads and associates, we now consider these conditions closely...Bibliography1. CastleRhoadsLawsonPayne WBCPHAGC: Etiology and treatment of sprue; observations on patients in Puerto Rico and subsequent experiments on animals, Arch. Int. Med. 56: 627-699 (Oct.) 1935. CrossrefGoogle Scholar2. CastleMinot WBGK: Pathological physiology and clinical description of the anemias, 1936, Oxford University Press, New York. Google Scholar3. Suarez RM: Clinical and hematological review of sprue based on the study of 150 cases, Ann. Int. Med. 12: 529, 1938. LinkGoogle Scholar4. Rodriguez-Molina R: Sprue in Puerto Rico: clinical study of 100 cases, Puerto Rico J. Pub. Health and Trop. Med. 17: 134-151 (Dec.) 1941. Google Scholar5. Ashford BK: A clinical investigation of tropical sprue, Bol. Asoc. med. de Puerto Rico 21: 1-26 (Mar.) 1923. Google Scholar6. Serra A: The relation of sprue to pernicious anemia, with a report on blood changes in 45 cases of sprue, Am. J. Trop. Med. 9: 49, 1929. CrossrefGoogle Scholar7. RomeroVizcarrondoRodriguez-Molina CARR: Treatment of sprue with folinic acid: report of nine cases, Am. J. M. Sc. 224: 9-22 (July) 1952. CrossrefMedlineGoogle Scholar8. Asenjo CF: Criteria for assessing fat absorption in normal subjects and sprue patients, Am. J. Trop. Med. and Hyg. 1: 344-352 (Mar.) 1952. CrossrefMedlineGoogle Scholar9. Thaysen TE: Nontropical sprue; a study in idiopathic steatorrhea (translated by Hans Andersen), 1932, Levin and Munksgaard, Copenhagen. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: RAFAEL RODRIGUEZ-MOLINA, F.A.C.P.Affiliations: San Juan, Puerto Rico*Presented at the Thirty-Fourth Annual Session of the American College of Physicians, Atlantic City, New Jersey, April 13, 1953. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byFolate in Tropical SprueAcute quadriparesis with muscle spasms related to electrolyte disturbances in steatorrheaRegarding the Definition of Tropical SprueCurrent Views on Tropical Sprue and a Comparison to Nontropical SprueNeuromuscular disease in patients with steatorrhoea.Tropical sprue and intussusception: An unusual associationThe structural and functional status of the liver in tropical sprueGastroenterology 1 January 1954Volume 40, Issue 1 Page: 33-41 Keywords Pernicious anemia ePublished: 1 December 2008 Issue Published: 1 January 1954 PDF downloadLoading ...