THE EFFECT OF DICUMAROL ON THE ERYTHROCYTE SEDIMENTATION RATE
Authors: R H WIER, J C EAGAN, S A WOLFSON
Journal: Annals of Internal Medicine (1950)

Article1 August 1950THE EFFECT OF DICUMAROL ON THE ERYTHROCYTE SEDIMENTATION RATEROBERT H. WIER, M.D., JOHN C. EAGAN, M.D., SAMUEL A. WOLFSON, M.D.ROBERT H. WIER, M.D.Search for more papers by this author, JOHN C. EAGAN, M.D.Search for more papers by this author, SAMUEL A. WOLFSON, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-33-2-354 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIt is generally agreed that the sedimentation rate of the erythrocytes is a valuable guide in the management of patients in a number of disease states, among which is coronary artery disease with myocardial infarction. Therefore, any form of therapy which could influence the rate would neutralize its value and thus deprive the physician of an excellent gauge of recovery. Such a possibility became apparent when Dicumarol was suggested in the treatment of myocardial infarction.In 1942 Allen, Barker and Waugh1stated that Dicumarol increased the sedimentation rate of the erythrocytes. However, in that same year, Wright and Prandoni2were...Bibliography1. AllenBarkerWaugh EVNWJM: A preparation from spoiled sweet clover 3,3′-methylene-bis-(4-hydroxycoumarin) which prolongs coagulation and prothrombin time of the blood; a clinical study, J. A. M. A. 120: 1009-1015, 1942. CrossrefGoogle Scholar2. WrightPrandoni ISA: The dicoumarin 3,3′-methylene-bis-(4-hydroxycoumarin); its pharmacologic and therapeutic action in man, J. A. M. A. 120: 1015-1021, 1942. CrossrefGoogle Scholar3. PetersGuytherBrambel HRJRCE: Dicumarol in acute coronary thrombosis, J. A. M. A. 130: 398-403, 1946. CrossrefMedlineGoogle Scholar4. AllenBarkerHines EVNWEA: Peripheral vascular diseases, 1946, W. B. Saunders Company, Philadelphia, Pa., p. 732. Google Scholar5. BarkerHinesKvaleAllen NWEAWFEV: Dicumarol; its action, clinical use and effectiveness as an anticoagulant drug, Am. J. Med. 3: 634-642, 1947. CrossrefMedlineGoogle Scholar6. Falk OP: Treatment of coronary artery disease; Dicumarol therapy, J. A. M. A. 134: 491-495, 1947. CrossrefMedlineGoogle Scholar7. Cosgriff SW: The effect of heparin and Dicumarol anticoagulant therapy upon the erythrocyte sedimentation rate, J. Clin. Investigation 27: 435-438, 1948. CrossrefMedlineGoogle Scholar8. Quick AJ: The nature of bleeding in jaundice, J. A. M. A. 110: 1658-1662, 1938. CrossrefGoogle Scholar9. Cutler JW: A standardized technique for sedimentation rate, J. Lab. and Clin. Med. 26: 542-552, 1940. Google Scholar10. PalmerGundersen JDSM: The effect of Dicumarol on the erythrocyte sedimentation rate in normal man, New England J. Med. 239: 818-819, 1948. CrossrefMedlineGoogle Scholar11. LitwinsVesellKissinCohenPaul JHMIA: Effect of Dicumarol on the erythrocyte sedimentation rate, J. A. M. A. 141: 330, 1949. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Los Angeles, California*Presented before the Los Angeles Heart Association, May 24, 1949. Received for publication November 7, 1949.From the Medical Service, Wadsworth Hospital, Veterans Administration Center, Los Angeles 24, California.Sponsored by the Veterans Administration and published with the approval of the Chief Medical Director. The statements and conclusions of the authors are the result of their own study and do not necessarily reflect the opinion or policy of the Veterans Administration. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe Effect of Dicumarolization On the Erythrocyte Sedimentation Rate in Dogs 1 August 1950Volume 33, Issue 2Page: 354-360KeywordsErythrocyte sedimentation rateHeart rateMedical servicesMyocardial infarctionStable coronary artery disease ePublished: 1 December 2008 Issue Published: 1 August 1950 PDF downloadLoading ...