Clinical and Psychological Patterns in Auto-erythrocyte Sensitivity
Authors: FREDERIC C. MCDUFFIE
Journal: Annals of Internal Medicine (1965)

Article1 August 1965Clinical and Psychological Patterns in Auto-erythrocyte SensitivityFREDERIC C. MCDUFFIE, M.D., FREDERICK L. MCGUIRE, PH.D.FREDERIC C. MCDUFFIE, M.D.Search for more papers by this author, FREDERICK L. MCGUIRE, PH.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-63-2-255 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAuto-erythrocyte sensitivity is a syndrome characterized by painful reddish lesions on the skin that come on very abruptly, and they rapidly become ecchymotic in character. Originally described by Gardner and Diamond in 1955 (1), 17 cases have now been reported (2-9). Since Gardner and Diamond observed that intradermal injection of red cell stroma could produce lesions resembling those seen clinically, they suggested that the cause of the disease might be autosensitivity to erythrocyte stroma. Little further light on this unusual syndrome was shed, however, until in 1961 Ratnoff and Agle (6, 7) called attention to the presence of numerous hysterical...References1. GARDNERDIAMOND FHLK: Autoerythrocyte sensitization: a form of purpura producing painful bruising following autosensitization to red blood cells in certain women. Blood 10: 675, 1955. CrossrefMedlineGoogle Scholar2. GOTTLIEBSTUPNIKERSANDBERGWOLDOW PMSHI: Erythrocyte autosensitization. Amer. J. Med. Sci. 233: 196, 1957. CrossrefMedlineGoogle Scholar3. HENSTELLKLIGERMAN HHM: Autosensitization to erythrocytes: a report of a case. California Med. 87: 267, 1957. MedlineGoogle Scholar4. REEDFIRKIN CSBG: Autoerythrocyte sensitization with a circulating fibrinolytic factor. Aust. Ann. Med. 6: 58, 1957. MedlineGoogle Scholar5. SHULMANFEIGONBITHELL NRJHTC: The role of histamine in the pathogenesis of a disease characterized by ecchymoses and systemic symptoms. Clin. Res. 7: 216, 1959. Google Scholar6. RATNOFFAGLE ODDP: Autoerythrocyte sensitization: psychiatric patterns in patients with a peculiar protracted purpura. Trans. Ass. Amer. Physicians 74: 290, 1961. MedlineGoogle Scholar7. AGLERATNOFF DPOD: Purpura as a psychosomatic entity: a psychiatric study of autoerythrocyte sensitization. Arch. Intern. Med. (Chicago) 109: 685, 1962. CrossrefMedlineGoogle Scholar8. MCCAY TS: Autoerythrocyte sensitization: a review and case report. J. Mississippi Med. Ass. 1: 559, 1960. Google Scholar9. DAVIDSON E: Factitious purpura presenting as autoerythrocyte sensitization. Brit. Med. J. i: 104, 1964. CrossrefGoogle Scholar10. DAHLSTROMWELSH WGGS: An MMPI Handbook: A guide to Use in Clinical Practice and Research. University of Minnesota Press, Minneapolis, 1960. Google Scholar11. GARDNER FH: Personal communication. Google Scholar12. LAWRENCE HS: The cellular transfer of cutaneous hypersensitivity to tuberculin in man. Proc. Soc. Exp. Biol. Med. 71: 516, 1949. CrossrefMedlineGoogle Scholar13. AGLE DP: Psychiatric studies of patients with hemophilia and related states. Arch. Int. Med. (Chicago) 114: 76, 1964. CrossrefMedlineGoogle Scholar14. ABRAMSONTEIGE HAE: Minnesota test as a guide to therapy in multiple sclerosis. Ann. NY Acad. Sci. 58: 648, 1954. CrossrefGoogle Scholar15. BALDWIN MV: A clinico-experimental investigation into the psychologic aspects of multiple sclerosis. J. Nerv. Ment. Dis. 115: 299, 1952. MedlineGoogle Scholar16. HECHTKROEBER STC: A study in prediction of attitudes of patients toward brief psychotherapy. Amer. Psychol. 10: 370, 1955. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Jackson, MississippiFrom the Departments of Medicine and Psychiatry, University of Mississippi Medical Center, Jackson, Miss.Presented in part at the Southeastern Regional Meeting of the American College of Physicians, Charleston, S. C., October 17, 1964.Reprint requests should be addressed to Frederic C. McDuffie, M.D., Section of Microbiology, Mayo Clinic, Rochester, Minn. 55902. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByCase of Gardner-Diamond syndrome after intramuscular stimulationAutoerythrocyte sensitization syndrome (Gardner-Diamond syndrome): review of the literature**The spectrum of plasminogen activator-dependent fibrinolysis-altered psychoinduced vasopermeability syndromeCase 39-1995Osteosynthetic Reconstruction in a Patient with Gardner-Diamond SyndromeDermatitis artefacta as the presenting feature of auto-erythrocyte sensitization syndrome and naproxen-induced pseudoporphyria in a single patientAnalysis of the family structure in a case of psychogenic purpuraAutoerythrocyte sensitization (Gardner-Diamond syndrome) in men: a case report and review of the literature.Psychosomatic dermatologyLes maladies factices et le syndrome de MünchausenThe autoerythrocyte sensitization syndrome as the primarymanifestation of systemic lupus erythematosusFactitious Fever and Self-Induced Infection A Report of 32 Cases and Review of the LiteratureROBERT P. ADUAN, M.D., ANTHONY S. FAUCI, M.D., DAVID C. DALE, M.D., JOSEPH H. HERZBERG, M.D., SHELDON M. WOLFF, M.D.PSYCHOTROPIC DRUGS IN DERMATOLOGIC PRACTICEMental Symptoms and Personality Structure in Autoerythrocyte Sensitization SyndromeAUTDERYTHROCYTE SEXSITIZATION SYNDROME (PAINFUL BRUISING SYNDROME).Factitious Purpura Simulating Autoerythrocyte SensitizationROBERT M. LEVIN, M.D., RONALD CHODOSH, M.D., JOSEPH D. SHERMAN, M.D., PH.D. 1 August 1965Volume 63, Issue 2Page: 255-265KeywordsAggressionIntradermal injectionsLesionsPatients Issue Published: 1 August 1965 PDF DownloadLoading ...