THE CHOICE OF OVARIAN OR PITUITARY THERAPY FOR MENSTRUAL DISTURBANCES
Authors: Elmer L. Sevringhaus
Journal: Annals of Internal Medicine (1939)

Article1 October 1939THE CHOICE OF OVARIAN OR PITUITARY THERAPY FOR MENSTRUAL DISTURBANCESELMER L. SEVRINGHAUS, F.A.C.P.ELMER L. SEVRINGHAUS, F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-13-4-629 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptDisturbances in menstrual rhythm or in fertility are far more frequently due to hypofunction than to an increased rate of ovarian hormone production. Regularly recurring cycles of increasing and decreasing intensity of secretion are characteristic of the hormones of the ovary. In this cyclic character of its hormone production the ovary is unique among the glands, unless it be the anterior pituitary in its gonadotropic secretion. The adjustment of the ovarian cycle is influenced by so many and diverse factors that disturbances in its rhythm are not surprising. Such impinging factors include the activity of other organs, nutrient and endocrine...Bibliography1. NOVAK E: Endocrine mechanisms in certain functional gynecologic disorders, Surg., Gynec. and Obst., 1935, lx, 330. BARTELMEZ, G. W.: Menstruation, Physiol. Rev., 1937, xvii, 28. ROCK, J., BARTLETT, M. K., and MATSON, D. D.: The incidence of anovulatory menstruation among patients of low fertility, Am. Jr. Obst. and Gynec., 1939, xxxvii, 3. Google Scholar2. FRANKSPIELMANGOLDBERGER RTFMA: Present endocrine diagnosis and therapy, Jr. Am. Med. Assoc., 1934, ciii, 393. CrossrefGoogle Scholar3. BURCHMCCLELLANJOHNSONELLISON JCGSCDET: The diagnosis and classification of menstrual disorders, Jr. Am. Med. Assoc., 1937, cviii, 96. CrossrefGoogle Scholar4. PAPANICOLAOUSHORR GNE: Action of ovarian follicular hormone in the menopause, as indicated by vaginal smears, Am. Jr. Obst. and Gynec., 1936, xxxi, 806. CrossrefGoogle Scholar5. ALBRIGHTHALSTEAD FJA: Studies on ovarian dysfunction, New England Jr. Med., 1935, ccxii, 250. CrossrefGoogle Scholar6. ISRAELMERANZEJOHNSTON SLDRCG: Inactivation of estrogen by the liver: fate of estrogen in heart-lung and heart-lung-liver perfusion systems, Am. Jr. Med. Sci., 1937, cxciv, 835. GOLDEN, J. B., and SEVRINGHAUS, E. L.: Inactivation of estrogenic hormone of the ovary by the liver, Proc. Soc. Exper. Biol. and Med., 1938, xxxix, 361. CrossrefGoogle Scholar7. KEMPPEDERSEN-BJERGAARD TK: Absorption and excretion of estrone by the human organism, Lancet, 1937, ii, 842. MAZER, C., and ISRAEL, S. L.: Optimal dosage of estrogens: experimental and clinical evaluation, Jr. Am. Med. Assoc., 1937, cviii, 163. CrossrefGoogle Scholar8. SCHOELLERDOHRNHOHLWEG WMW: Problem of standardization of follicle hormone and its derivatives, Klin. Wchnschr., 1935, xiv, 339. Google Scholar9. CAMPBELLLENDRUMSEVRINGHAUS REFCEL: Endometrial histology and pathology as revealed by biopsy method, Surg., Gynec. and Obst., 1936, lxiii, 724. Google Scholar10. VENNING EH: Further studies on the estimation of small amounts of sodium pregnandiol glycuronidate in urine, Jr. Biol. Chem., 1938, cxxvi, 595. CrossrefGoogle Scholar11. WILSONRANDALLOSTERBERG RBLMRE: Studies on pregnandiol, Am. Jr. Obst. and Gynec., 1939, xxxvii, 59. CrossrefGoogle Scholar12. LAUSONGOLDENSEVRINGHAUS HDJBEL: The gonadotropic content of the hypophysis throughout the life cycle of the normal female rat, Am. Jr. Physiol., 1939, cxxv, 396. CrossrefGoogle Scholar13. HELLERHELLER CGEJ: Gonadotropic hormone: urine assays of normally cycling, menopausal, castrated, and estrin treated human females, Jr. Clin. Invest., 1939, xviii, 171. CrossrefGoogle Scholar14. CAMPBELLSEVRINGHAUS REEL: Pituitary gonadotropic extracts for treatment of amenorrhea, menorrhagia, and sterility, Am. Jr. Obst. and Gynec., 1939, xxxvii, 913. CrossrefGoogle Scholar15. WATSONSMITHKURZROK BPPER: Relation of the pituitary gland to the menopause, Am. Jr. Obst. and Gynec., 1938, xxxvi, 562. CrossrefGoogle Scholar16. SCHNEIDER PF: A syndrome suggestive of ovarian deficiency, Am. Jr. Obst. and Gynec., 1936, xxxi, 782. CrossrefGoogle Scholar17. ALLENDIDDLE EAW: Ovarian follicular hormone effects on ovaries, Am. Jr. Obst. and Gynec., 1935, xxix, 83. FOSS, G. L.: Temporary postponement of menstruation by estradiol benzoate, Brit. Med. Jr., 1937, vii, 10. CrossrefGoogle Scholar18. FEVOLDHISAWGREEP HLFLR: Effect of oestrin on the activity of the anterior lobe of the pituitary, Am. Jr. Physiol., 1936, cxiv, 508. Google Scholar19. SEVRINGHAUS EL: Relief of menopause symptoms by estrogenic preparations, Jr. Am. Med. Assoc., 1935, civ, 624. CrossrefGoogle Scholar20. HISAW FL: Personal communication. FEVOLD, H. L.: The follicle stimulating and luteinizing hormones of the anterior pituitary, Chap. xvii in "Sex and internal secretions," by ALLEN, E., et al., 1939, Williams and Wilkins Co., Baltimore. Google Scholar21. FOSTERHISAW MAFL: Experimental ovulation and resulting pseudopregnancy in anestrus cats, Anat. Rec., 1935, lxii, 75. DAVIS, M. E., and KOFF, A. K.: Experimental production of ovulation in human subjects, Am. Jr. Obst. and Gynec., 1938, xxxvi, 183. CrossrefGoogle Scholar22. HISAW FL: The physiology of menstruation in Macacus rhesus monkeys, Am. Jr. Obst. and Gynec., 1935, xxix, 638. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Madison, Wisconsin*Read at the New Orleans meeting of the American College of Physicians March 27, 1939. 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