THE SIGNIFICANCE OF GASTRIC ACIDITY AFTER HISTAMINE STIMULATION: A STATISTICAL STUDY OF 2877 GASTRIC ANALYSES
Authors: Julian M. Ruffin, Macdonald Dick
Journal: Annals of Internal Medicine (1939)

Article1 June 1939THE SIGNIFICANCE OF GASTRIC ACIDITY AFTER HISTAMINE STIMULATION: A STATISTICAL STUDY OF 2877 GASTRIC ANALYSESJULIAN M. RUFFIN, M.D., MACDONALD DICK, M.D.JULIAN M. RUFFIN, M.D.Search for more papers by this author, MACDONALD DICK, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-12-12-1940 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptMost of the reports of gastric analyses which have appeared previously in the literature1, 2, 3are based upon values obtained after a test meal of the Ewald type. It is well known that the administration of histamine is the most reliable method of evoking gastric secretion.4, 5Since the opening of Duke Hospital in 1930 all gastric analyses here have been made with the use of this drug, and examinations of the contents of the stomach by this method have been made in 3675 patients. It seems profitable, therefore, to examine these data critically in order to determine whether...Bibliography1. VANZANTALVAREZEUSTERMANDUNNBERKSON FRWGGBHLJ: The normal range of gastric acidity from youth to old age: an analysis of 3746 records, Arch. Int. Med., 1932, xlix, 345. CrossrefGoogle Scholar2. VANZANTALVAREZBERKSONEUSTERMAN FRWCJGB: Changes in gastric acidity in peptic ulcer, cholecystitis and other diseases analyzed with help of new and accurate technic, Arch. Int. Med., 1933, lii, 616. CrossrefGoogle Scholar3. SAGALMARKSKANTOR ZJAJL: The clinical significance of gastric acidity: a study of 6679 cases with digestive symptoms, ANN. INT. MED., 1933, vii, 76. LinkGoogle Scholar4. BESTTAYLOR CHNB: Physiological basis of medical practice, 1937, William Wood Company, Baltimore. Google Scholar5. BLOOMFIELDPOLLARD ALWS: Gastric anacidity: its relation to disease, 1933, Macmillan, New York. Google Scholar6. Principles of medical statistics, The Lancet Limited, 1937, London. Google Scholar7. HARTUNGSTEINBROCKER EFO: Gastric acidity in chronic arthritis, ANN. INT. MED., 1935, ix, 252. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Durham, North Carolina*Received for publication August 25, 1938.From the Departments of Medicine and Physiology, Duke University School of Medicine, Durham, N. C.†We wish to acknowledge the assistance of A. F. Henderson, M.D., H. F. Swingle, M.D., and J. B. Stevens, M.D. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDisturbed gastroduodenal motility in patients with active and healed duodenal ulcerationPostbulbar duodenal ulcer in a patient with pentagastrin-fast achlorhydriaMagenGASTRIC ACIDITY BEFORE AND AFTER DEVELOPMENT OF GASTRIC CANCER: ITS ETIOLOGIC, DIAGNOSTIC AND PROGNOSTIC SIGNIFICANCE*MANDRED W. COMFORT, M.D., F.A.C.P.THE MECHANISM OF HYDROCHLORIC ACID PRODUCTION BY THE STOMACHPeptic Ulcer in Man Part 5. A new Antacid, SCMC, made to meet requirements of Antacid Therapy. Clinical EvaluationAchlorhydria and Duodenal Ulcer: A Report of Two Cases Having Achlorhydria and Diagnosed as Duodenal Ulcer not Proven at SurgeryBenign Gastric Ulcers Occurring in the Presence of AchlorhydriaHow Often is There Value in the Giving of Hydrochloric Acid?A Study of Gastric HCl FormationGastric acidity in pulmonary tuberculosisThe effect of gastric hypersecretion on the reaction and neutralizing ability of the contents of the first part of the duodenum in normal dogs 1 June 1939Volume 12, Issue 12Page: 1940-1947KeywordsDrug administrationDrugsHistamineStomach ePublished: 1 December 2008 Issue Published: 1 June 1939 PDF downloadLoading ...