BACTERIOLOGIC CULTURE OF THE DISEASED HUMAN LIVER
Authors: J M STORMONT, J E MACKIE, E H KASS, C S DAVIDSON
Journal: Annals of Internal Medicine (1959)

Article1 July 1959BACTERIOLOGIC CULTURE OF THE DISEASED HUMAN LIVERJAMES M. STORMONT, M.D., JOSEPH E. MACKIE, M.D., EDWARD H. KASS, M.D., F.A.C.P., CHARLES S. DAVIDSON, M.D.. F.A.C.P.JAMES M. STORMONT, M.D.Search for more papers by this author, JOSEPH E. MACKIE, M.D.Search for more papers by this author, EDWARD H. KASS, M.D., F.A.C.P.Search for more papers by this author, CHARLES S. DAVIDSON, M.D.. F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-51-1-17 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe role of bacteria in the pathogenesis of liver disease is uncertain. In ascending cholangitis, bacteria frequently invade the liver; however, in other types of liver disease, bacterial invasion of the liver often has been postulated but has not been demonstrated. The action of intestinal bacteria in the production of experimental cirrhosis in rats has been studied,1, 2 but it is difficult to transfer these findings to human cirrhosis.Postmortem liver and portal vein cultures in the human have grown out intestinal bacteria within 30 minutes after death.3-5Cultures of the liver by means of the Vim-Silverman biopsy needle, peritoneoscopic...Bibliography1. Gyorgy P: Antibiotics and liver disease, Ann. New York Acad. Sc. 57: 925, 1954. CrossrefMedlineGoogle Scholar2. RutenburgSonnenblickKonenAprahamianReinerFine AMEIHALJ: The role of intestinal bacteria in the development of dietary cirrhosis in rats, J. Exper. Med. 106: 1, 1957. CrossrefMedlineGoogle Scholar3. Ford WW: The bacteriology of healthy organs, Tr. A. Am. Physicians 15: 389, 1900. Google Scholar4. MasonHart ECMS: The Welch-like bacillus in human liver, J. Lab. and Clin. Med. 25: 835, 1940. Google Scholar5. SborovMorseGigesJahnke VMWCBEJ: Bacteriology of the human liver, J. Clin. 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SchattenDesprezHolden WEJDWD: Bacteriologic study of portal-vein blood in man, Arch. Surg. 71: 404, 1955. CrossrefGoogle Scholar20. Taylor FW: Blood culture studies of the portal vein, Arch. Surg. 72: 889, 1956. CrossrefGoogle Scholar21. TopleyWilson WWGS: Principles of bacteriology and immunity, Wilson, G. S., and Miles, A. A., Editors, 1957, The Williams & Wilkins Company, Baltimore, p. 1186. Google Scholar22. FastWolfeStormontDavidson BBSJJMCS: Antibiotic therapy in the management of hepatic coma, Arch. Int. Med. 101: 467, 1958. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Boston, Massachusetts*Received for publication August 4, 1958.From the Thorndike Memorial Laboratory and the Second and Fourth (Harvard) Medical Services, Boston City Hospital, and the Departments of Medicine and Bacteriology, Harvard Medical School.†This work was supported in part by the Office of the Surgeon General, Department of the Army, in part by the National Institutes of Health, U. S. Public Health Service, and in part by a grant from Merck Sharp & Dohme, Division of Merck & Co., Inc., Philadelphia, to Harvard University.Requests for reprints should be addressed to Charles S. Davidson, M.D., Thorndike Memorial Laboratory, Boston City Hospital, Boston 18, Massachusetts. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byTranslocation of Indigenous Bacteria from the Intestinal TractAscending cholangitis diagnosed by percutaneous hepatic aspirationAnaerobic Bacteriological Study of the Human Liver — with a Critical Review of the LiteratureLeukemoid Reaction, Hyperuricemia, and Severe Hyperpyrexia Complicating a Fatal Case of Acute Fatty Liver of the AlcoholicROBERT W. COLMAN, M.D., HARVEY M. SHEIN, M.D. 1 July 1959Volume 51, Issue 1Page: 17-22KeywordsBacteriaCirrhosisHospital medicineLiverLiver diseasesMedical servicesPortal veinsPrevention, policy, and public healthResearch laboratoriesSurgeons ePublished: 1 December 2008 Issue Published: 1 July 1959 PDF downloadLoading ...