PRIMARY HYPERPARATHYROIDISM DUE TO A PARATHYROID ADENOMA: ANTEMORTEM DIAGNOSIS WITH TERMINATION IN POSSIBLE ACUTE PARATHYROID HORMONE INTOXICATION
Authors: W HOROWITZ, A A BERENBAUM
Journal: Annals of Internal Medicine (1958)

Case Reports1 July 1958PRIMARY HYPERPARATHYROIDISM DUE TO A PARATHYROID ADENOMA: ANTEMORTEM DIAGNOSIS WITH TERMINATION IN POSSIBLE ACUTE PARATHYROID HORMONE INTOXICATIONWILLIAM HOROWITZ, M.D., F.A.C.P, ARTHUR A. BERENBAUM, M.D.WILLIAM HOROWITZ, M.D., F.A.C.PSearch for more papers by this author, ARTHUR A. BERENBAUM, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-49-1-181 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptPrimary hyperparathyroidism was seldom diagnosed during life prior to 1925. Twenty-six of 27 recorded cases from 1903 to 1925 were diagnosed at autopsy.1The pioneer work of Mandl2in 1926, consisting in the removal of a parathyroid adenoma from a patient suffering from osteitis fibrosa cystica, with remarkable improvement, and the reported extraction of a parathyroid hormone by Collip,3caused an immediate upsurge in the seeking out of cases of hyperparathyroidism. The subsequent classic studies carried out by Albright and co-workers12a, b, c, daided greatly in establishing hyperparathyroidism as a well defined clinical entity. A higher index of suspicion...Bibliography1. BodanskyBodansky MO: Biochemistry of disease, 2nd Ed., 1952, The Macmillan Co., New York. Google Scholar2. Mandl F: Klinisches und Experimentelles zur Frage der lokalisierten und generalisierten Ostitis fibrosa, Arch. f. klin. Chir. 143: 245, 1926. Google Scholar3. Collip JB: The extraction of a parathyroid hormone which will prevent or control tetany and which regulates the level of blood calcium, J. Biol. Chem. 63: 395-438, 1925. CrossrefGoogle Scholar4. Snapper I: Medical clinics on bone diseases: a text and atlas, 2nd Ed., 1949, Interscience Publishers, New York. Google Scholar5. GutmanSwensonParsons ABPCWB: The differential diagnosis of hyperparathyroidism, J. A. M. A. 103: 87-94 (July 4) 1934. CrossrefGoogle Scholar6. AtlasGabermanEisenberg DHPHL: Syndrome of masked hyperparathyroidism, Ann. Int. Med. 44: 1195-1210, 1956. LinkGoogle Scholar7. Plimpton CH: Calcium metabolism in health and disease, M. Clin. North America 39: 881-898 (May) 1955. CrossrefGoogle Scholar8. ReifensteinHoward ECRP: Glandular physiology and therapy, 5th Ed., 1954, Lippincott, Philadelphia, p. 351. Google Scholar9. Hanes FW: Hyperparathyroidism due to parathyroid adenoma with death from parathormone intoxication, Am. J. M. Sc. 197: 85-90, 1939. CrossrefGoogle Scholar10. ThornForshamGoldfien GWPHA: Harrison's Principles of internal medicine, 2nd Ed., 1954, The Blakiston Company, New York, pp. 622-632. Google Scholar11. Wright S: Applied physiology, 1945, Oxford University Press, London. Google Scholar12. AlbrightReifenstein FEC (a) : Parathyroid glands and metabolic bone disease, 1948, The Williams and Wilkins Co., Baltimore. (b) Albright, F., Baird, P. C., Cope, O., and Bloomberg, E.: Studies on physiology of parathyroid glands; renal complications of hyperparathyroidism, Am. J. M. Sc. 187: 49-65, 1934. (c) Albright, F., Aub, J. C., and Bauer, W.: Hyperparathyroidism; common and polymorphic condition as illustrated by 17 proved cases from one clinic, J. A. M. A. 102: 1276-1287 (Apr. 21) 1934. (d) Albright, F., Sulkowitch, H. W., and Bloomberg, E.: Hyperparathyroidism due to idiopathic hypertrophy (hyperplasia?) of parathyroid tissue, Arch. Int. Med. 62: 199-215, 1938. Google Scholar13. Carnes WH: The demonstration of an effect of parathyroid extract on bone matrix, Am. J. Path. 26: 736, 1950. Google Scholar14. Selye H: Mechanism of parathyroid hormone action, Arch. Path. 34: 625-633 (Oct.) 1942. Google Scholar15. Grollman A: Role of the kidney in the parathyroid control of the blood calcium as determined by studies on the nephrectomized dog, Endocrinology 55: 166 (Aug.) 1954. CrossrefMedlineGoogle Scholar16. Munson PL: Studies on the role of parathyroids in calcium and phosphorus metabolism, Ann. New York Acad. Sc. 60: 776-794, 1955. CrossrefMedlineGoogle Scholar17. Zondek H: The diseases of the endocrine glands, 4th Ed., 1944, The Williams and Wilkins Co., Baltimore. Google Scholar18. GreenwoodBestWinston JHEBJR: Dysfunction of the parathyroid glands, M. Clin. North America 39: 1153-1169 (July) 1955. CrossrefGoogle Scholar19. Hueper W: Metastatic calcifications in the organs of the dog after injections of parathyroid extract, Arch. Path. 3: 14, 1927. Google Scholar20. CantarowStewartHousel AHLEL: Experimental acute hyperparathyroidism, Endocrinology 22: 13-27, 1938. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication December 15, 1956.From the Medical Service of Herman L. Frosch, M.D., F.A.C.P. Lebanon Hospital, Bronx, N. Y., and the Department of Internal Medicine, Graduate School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.Requests for reprints should be addressed to Arthur A. Berenbaum, M.D., 1923 Spruce Street, Philadelphia 3, Pennsylvania. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPrimary hyperparathyroidismRenal vein thrombosis complicating primary hyperparathyroidismChanges in Parathyroid Metabolism Following Ureterolithotomy in a Patient with HyperparathyroidismCase 21-1964Calcium Intoxication Due to Primary Hyperparathyroidism A Medical and Surgical EmergencyJACOB LEMANN JR., M.D., ANTHONY A. DONATELLI, M.D.Endocrine Emergencies (Nondiabetic)Acute Hyperparathyroidism and Acute PancreatitisPrimary Hyperparathyroidism With Acute Parathyroid Hormone IntoxicationDeath Due to Parathyroid CrisisRecurrent Acute Hyperparathyroidism with Severe Gastrointestinal Manifestations 1 July 1958Volume 49, Issue 1Page: 181-189KeywordsAdenomasCalciumComaHospital medicineHypercalcemiaHyperparathyroidismIntoxicationParathyroid hormoneParathyroid tumorsPhosphatases ePublished: 1 December 2008 Issue Published: 1 July 1958 PDF downloadLoading ...