Cardiopulmonary Function in Young Smokers
Authors: RICHARD A. KRUMHOLZ
Journal: Annals of Internal Medicine (1964)

Article1 April 1964Cardiopulmonary Function in Young SmokersA Comparison of Pulmonary Function Measurements and Some Cardiopulmonary Responses to Exercise Between a Group of Young Smokers and a Comparable Group of NonsmokersRICHARD A. KRUMHOLZ, M.D., ROBERT B. CHEVALIER, M.D., JOSEPH C. ROSS, M.D.RICHARD A. KRUMHOLZ, M.D., ROBERT B. CHEVALIER, M.D., JOSEPH C. ROSS, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-60-4-603 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIt has previously been reported that smokers develop a greater oxygen debt during exercise than nonsmokers (1). This investigation was designed to study the effect of chronic cigarette smoking on the accumulation and repayment of oxygen debt during exercise and on some aspects of pulmonary function and to evaluate the possible correlation of the increased oxygen debt with pulmonary function abnormalities. The studies were carried out in young men who were similar in body surface area, age, and occupation.Extensive pulmonary function studies including pulmonary diffusing capacity for carbon monoxide (DL) as well as oxygen consumption and heart rate were...References1. CHEVALIERBOWERSBONDURANTROSS RBJASJC: Circulatory and ventilatory effects of exercise in smokers and non-smokers. J. Appl. Physiol. 118: 357, 1963. CrossrefGoogle Scholar2. ABARQUEZFREIMANREICHELLADUE RFAHFJS: The precordial electrocardiogram during exercise. Circulation 22: 1060, 1960. CrossrefMedlineGoogle Scholar3. KROGH M: Diffusion of gases through the lungs of man. J. Physiol. (London) 49: 271, 1914. CrossrefGoogle Scholar4. FORSTERFOWLERBATESVAN LINGEN REWSDVB: The absorption of carbon monoxide by the lungs during breath holding. J. Clin. Invest. 33: 1135, 1954. CrossrefMedlineGoogle Scholar5. 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ROSS, M.D.Affiliations: Indianapolis, IndianaFrom the Department of Medicine and the Heart Research Center, Indiana University Medical Center, and the Krannert Heart Research Institute, Marion County General Hospital, Indianapolis, Indiana.This work was supported in part by Purdue Farm Cardiac Project Grant OH91 and by research grants HE-06228 and HE-04080, all from the National Heart Institute, National Institutes of Health, United States Public Health Service, Bethesda, Maryland, and in part by the Indiana Heart Association.Dr. Krumholz is a Postgraduate Research Fellow of the United States Public Health Service.Requests for reprints should be addressed to Joseph C. Ross, M.D., Indiana University Medical Center, 1100 West Michigan Street, Indianapolis 7, Indiana. 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ROSS, M.D. 1 April 1964Volume 60, Issue 4Page: 603-610KeywordsExerciseHeartHeart rateHospital medicineMedical servicesOxygenOxygen consumptionPrevention, policy, and public healthPulmonary functionResearch grants ePublished: 1 December 2008 Issue Published: 1 April 1964 PDF downloadLoading ...