TOLERANCE TO BENZEDRINE SULFATE
Authors: Leon J. Robinson
Journal: Annals of Internal Medicine (1938)

Case Reports1 August 1938TOLERANCE TO BENZEDRINE SULFATELEON J. ROBINSON, M.D.LEON J. ROBINSON, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-12-2-255 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn 1935 Prinzmetal and Bloomberg1introduced benzedrine (phenylisopropylamine), a comparatively new sympathomimetic for the treatment of narcolepsy. Its dramatic success in this condition stimulated many investigations of additional therapeutic indications for the use of the systemic effects of benzedrine, as well as verification of its value in narcolepsy.2It has been demonstrated that benzedrine relaxes gastrointestinal spasm3; ameliorates apathy and depression in normals and in neurotic persons,4and in post-encephalitic Parkinsonism5; aborts marked drop in blood pressure during spinal anesthesia6; and prevents syncope caused by orthostatic hypotension.7We have found it efficacious in the prevention of carotid sinus syncope of...References1. PRINZMETALBLOOMBERG MW: The use of benzedrine for the treatment of narcolepsy, Jr. Am. Med. Assoc., 1935, cv, 2051-2054. CrossrefGoogle Scholar2. ULRICHTRAPPVIDGOFF HCEB: The treatment of narcolepsy with benzedrine sulfate, ANN. INT. MED., 1936, ix, 1213-1221. Google Scholar3. MYERSONRITVO AM: Benzedrine sulfate and its value in spasm of the gastrointestinal tract, Jr. Am. Med. Assoc., 1936, cvii, 24-26. CrossrefGoogle Scholar4. MYERSON A: Effect of benzedrine sulfate on mood and fatigue in normal and in neurotic persons, Arch. Neurol. and Psychiat., 1936, xxxvi, 816-822. CrossrefGoogle Scholar5. SOLOMONMITCHELLPRINZMETAL PRSM: The use of benzedrine sulfate in postencephalitic Parkinson's disease, Jr. Am. Med. Assoc., 1937, cviii, 1765-1770. CrossrefGoogle Scholar6. TOVELL RM: Control of blood pressure during spinal anesthesia: preliminary report, Proc. Staff Meet. Mayo Clinic, 1936, ii, 585-588. Google Scholar7. DAVISSHUMWAY-DAVIS PLM: Orthostatic hypotension: the treatment of two cases with benzedrine sulfate, Jr. Am. Med. Assoc., 1937, cviii, 1247-1249. CrossrefGoogle Scholar8. ROBINSON LJ: Benzedrine sulfate in the treatment of syncope due to a hyperactive carotid sinus reflex, New Eng. Jr. Med., 217 (to be published). Google Scholar9. WILBURMACLEANALLEN DLAREV: Clinical observations on the effect of benzedrine sulfate, Jr. Am. Med. Assoc., 1937, cix, 549-554. CrossrefGoogle Scholar10. WEISSCAPPSFERRISMUNRO SRBEBD: Syncope and convulsions due to a hyperactive carotid sinus reflex, Arch. Int. Med., 1936, lviii, 407-417. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Palmer, Massachusetts*Received for publication September 30, 1937. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byÜber außermedizinische Verwendung der Weckamine und das Problem der LeistungssteigerungBenzedrine Sulphate in Clinical Medicine 1 August 1938Volume 12, Issue 2Page: 255-258KeywordsBlood pressureNarcolepsySulfatesSyncope ePublished: 1 December 2008 Issue Published: 1 August 1938 PDF downloadLoading ...