OCCURRENCE OF INFECTIOUS MONONUCLEOSIS AND SYPHILIS IN THE SAME INDIVIDUAL
Authors: C J D ZARAFONETIS
Journal: Annals of Internal Medicine (1953)

Case Reports1 May 1953OCCURRENCE OF INFECTIOUS MONONUCLEOSIS AND SYPHILIS IN THE SAME INDIVIDUALC. J. D. ZAKAFONETIS, M.D., F.A.C.P.C. J. D. ZAKAFONETIS, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-38-5-1053 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptInfectious mononucleosis and syphilis are notable for their widely varied clinical manifestations. It is also recognized that the differential diagnosis between these conditions may be very difficult under certain circumstances. This is readily apparent when it is recalled that malaise, lassitude, headache, myalgia, fever, sore throat, generalized lymphadenopathy and skin rash are features common to infectious mononucleosis and secondary syphilis. Fortunately, differentiation is usually possible through the use of appropriate laboratory studies. These include repeated examinations of the blood for the appearance of the leukocyte changes associated with infectious mononucleosis, and serial heterophil agglutination tests to detect agglutinins for sheep...Bibliography1. Kahn RL: Are there paradoxic serologic reactions in syphilis? Arch. Dermat. and Syph. 39: 92, 1939. CrossrefGoogle Scholar2. Bernstein A: Infectious mononucleosis, Medicine 19: 85, 1940. CrossrefGoogle Scholar3. Kaufman RE: False positive reactions for syphilis in infectious mononucleosis, J. Lab. and Clin. Med. 26: 1439, 1941. Google Scholar4. WechslerRosenblumSills HFAHCT: Infectious mononucleosis: report of an epidemic in an Army post, Ann. Int. Med. 25: 113, 1946. LinkGoogle Scholar5. ZarafonetisKent CJJF: Serologic tests for syphilis in infectious mononucleosis, to be published. Google Scholar6. Zarafonetis CJ: Infectious mononucleosis, Journal-Lancet 69: 364, 1949. MedlineGoogle Scholar7. ZarafonetisOster CJHL: Heterophile agglutination variability of erythrocytes from different sheep, J. Lab. and Clin. Med. 36: 283, 1950. MedlineGoogle Scholar8. BaldridgeRohnerHansmann CWEJGH: Glandular fever (infectious mononucleosis), Arch. Int. Med. 38: 413, 1926. CrossrefGoogle Scholar9. White EC: Lymphadenosis, an acute benign disease simulating acute leukemia, U. S. Nav. M. Bull. 22: 302, 1925. Google Scholar10. Farley DL: Acute infectious mononucleosis, M. Clin. North America 21: 1139, 1937. CrossrefGoogle Scholar11. GendelCottrell BRJE: Infectious mononucleosis: a review, Am. Pract. 2: 472, 1948. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Philadelphia, Pennsylvania*Received for publication November 5, 1952.From the Departments of Internal Medicine, University of Michigan Medical School and Temple University Medical School.†Part of a broader study of infectious mononucleosis made possible by a grant from the Charles Stewart Mott Foundation. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byFurther Progress in Venereology 1 May 1953Volume 38, Issue 5Page: 1053-1057KeywordsFatigueFeversHematologic testsMyalgiaPharyngitisRashesResearch laboratoriesSecondary headachesSkin infectionsSyphilis ePublished: 1 December 2008 Issue Published: 1 May 1953 PDF downloadLoading ...