Screening for Vitamin D Deficiency
Authors: Erin S. LeBlanc, Roger Chou, Miranda Pappas
Journal: Annals of Internal Medicine (2015)

Letters19 May 2015Screening for Vitamin D DeficiencyErin S. LeBlanc, MD, MPH, Roger Chou, MD, and Miranda Pappas, MAErin S. LeBlanc, MD, MPHFrom Center for Health Research, Kaiser Permanente Northwest, and Pacific Northwest Evidence-based Practice Center, Oregon Health & Science University, Portland, Oregon.Search for more papers by this author, Roger Chou, MDFrom Center for Health Research, Kaiser Permanente Northwest, and Pacific Northwest Evidence-based Practice Center, Oregon Health & Science University, Portland, Oregon.Search for more papers by this author, and Miranda Pappas, MAFrom Center for Health Research, Kaiser Permanente Northwest, and Pacific Northwest Evidence-based Practice Center, Oregon Health & Science University, Portland, Oregon.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/L15-5094-4 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:The purpose of our systematic review was to determine whether screening for vitamin D deficiency in asymptomatic persons improved health outcomes. Therefore, we determined a priori that we would include only studies of populations that had documented vitamin D deficiency and were not selected on the basis of a history of osteoporosis, prior fractures, or falls. Thus, we included fewer studies than the meta-analyses by Dr. Bolland and colleagues (1, 2), which also included trials of participants with normal vitamin D levels and with osteoporosis and prior fractures or falls. We did not exclude any study solely because ...References1. Bolland MJ, Grey A, Gamble GD, Reid IR. Vitamin D supplementation and falls: a trial sequential meta-analysis. Lancet Diabetes Endocrinol. 2014;2:573-80. [PMID: 24768505] doi:10.1016/S2213-8587(14)70068-3 CrossrefMedlineGoogle Scholar2. Bolland MJ, Grey A, Gamble GD, Reid IR. The effect of vitamin D supplementation on skeletal, vascular, or cancer outcomes: a trial sequential meta-analysis. Lancet Diabetes Endocrinol. 2014;2:307-20. [PMID: 24703049] doi:10.1016/S2213-8587(13)70212-2 CrossrefMedlineGoogle Scholar3. Chapuy MC, Arlot ME, Duboeuf F, Brun J, Crouzet B, Arnaud S, et al. Vitamin D3 and calcium to prevent hip fractures in the elderly women. N Engl J Med. 1992;327:1637-42. [PMID: 1331788] CrossrefMedlineGoogle Scholar4. Chapuy MC, Pamphile R, Paris E, Kempf C, Schlichting M, Arnaud S, et al. Combined calcium and vitamin D3 supplementation in elderly women: confirmation of reversal of secondary hyperparathyroidism and hip fracture risk: the Decalyos II study. Osteoporos Int. 2002;13:257-64. [PMID: 11991447] CrossrefMedlineGoogle Scholar5. Heaney RP, Armas LA. Screening for vitamin D deficiency: is the goal disease prevention or full nutrient repletion? [Editorial]. Ann Intern Med. 2015;162:144-5. [PMID: 25420050] doi:10.7326/M14-2573 LinkGoogle Scholar Author, Article, and Disclosure InformationAuthors: Erin S. LeBlanc, MD, MPH; Roger Chou, MD; Miranda Pappas, MAAffiliations: From Center for Health Research, Kaiser Permanente Northwest, and Pacific Northwest Evidence-based Practice Center, Oregon Health & Science University, Portland, Oregon.Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M14-1659. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoScreening for Vitamin D Deficiency: A Systematic Review for the U.S. Preventive Services Task Force Erin S. LeBlanc , Bernadette Zakher , Monica Daeges , Miranda Pappas , and Roger Chou Screening for Vitamin D Deficiency: A Systematic Review for the U.S. Preventive Services Task Force Erin S. LeBlanc , Bernadette Zakher , Monica Daeges , Miranda Pappas , and Roger Chou Screening for Vitamin D Deficiency Mark J. Bolland , Andrew Grey , and Ian R. Reid Screening for Vitamin D Deficiency Kirti Kain Screening for Vitamin D Deficiency Toshihiro Sugiyama , Yoon Taek Kim , and Hiromi Oda Screening for Vitamin D Deficiency Kirti Kain Screening for Vitamin D Deficiency Toshihiro Sugiyama , Yoon Taek Kim , and Hiromi Oda Screening for Vitamin D Deficiency Mark J. Bolland , Andrew Grey , and Ian R. Reid Metrics Cited byVitamin D screening 19 May 2015Volume 162, Issue 10Page: 738KeywordsDisclosureFactor analysisFallsOsteoporosisPopulation statisticsSystematic reviewsVitamin DVitamin D deficiency ePublished: 19 May 2015 Issue Published: 19 May 2015 Copyright & PermissionsCopyright © 2015 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...