VASOMOTOR EFFECTS OF BLOOD IN PATIENTS WITH HYPERTENSION AND ANIMALS WITH EXPERIMENTAL HYPERTENSION
Authors: Ben Friedman, Myron Prinzmetal
Journal: Annals of Internal Medicine (1939)

Article1 April 1939VASOMOTOR EFFECTS OF BLOOD IN PATIENTS WITH HYPERTENSION AND ANIMALS WITH EXPERIMENTAL HYPERTENSIONBEN FRIEDMAN, MYRON PRINZMETALBEN FRIEDMANSearch for more papers by this author, MYRON PRINZMETALSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-12-10-1617 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptRecent investigations have suggested that the abnormal vasoconstriction in animals and patients with persistent hypertension is due to a non-nervous and presumably chemical mechanism.1, 2, 3, 4, 5Increased amounts of a pressor substance have been demonstrated in saline extracts made from kidneys of dogs with renal hypertension and from kidneys of patients suffering from hypertensive disease.6, 7These observations are compatible with the hypothesis that such forms of hypertension are due to the humoral accumulation of a pressor substance of renal origin. 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Author, Article, and Disclosure InformationAffiliations: *Received for publication March 26, 1938.Preliminary reports of this paper have appeared:FRIEDMAN, B., and PRINZMETAL, M.: Vasomotor effects of blood in hypertension, Proc. Soc. Exper. Biol. and Med., 1936, xxxiv, 543.PRINZMETAL, M., FRIEDMAN, B., and ROSENTHAL, N.: Nature of peripheral resistance in arterial hypertension, Ibid., 1936, xxxiv, 546.†Work done during the tenure of Richard and Ella Hunt Sutro Fellowships.From the Medical Service of Dr. B. S. Oppenheimer at Mount Sinai Hospital, New York City. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byTHE VASOCONSTRICTOR PROPERTIES OF THE VENA CAVA BLOOD OF DOGS WITH ACUTE AND CHRONIC RENAL HYPERTENSION1Die Sympathektomie beim Hochdruck und ihre ErgebnisseAttempts to Demonstrate the Presence of Pressor Substance in the Blood of Patients with Renal Hypertension1Reciprocal Transfusions of Blood in Anuria: Report of a Case 1 April 1939Volume 12, Issue 10Page: 1617-1631KeywordsBloodFellowshipsHypertensionKidneysMedical servicesVasoconstriction ePublished: 1 December 2008 Issue Published: 1 April 1939 PDF downloadLoading ...