THE MANIFESTATIONS IN THE SKIN AND MUCOUS MEMBRANES IN DERMATOMYOSITIS, WITH SPECIAL REFERENCE TO THE DIFFERENTIAL DIAGNOSIS FROM SYSTEMIC LUPUS ERYTHEMATOSUS
Authors: Harry Keil
Journal: Annals of Internal Medicine (1942)

Article1 May 1942THE MANIFESTATIONS IN THE SKIN AND MUCOUS MEMBRANES IN DERMATOMYOSITIS, WITH SPECIAL REFERENCE TO THE DIFFERENTIAL DIAGNOSIS FROM SYSTEMIC LUPUS ERYTHEMATOSUSHARRY KEIL, M.D.HARRY KEIL, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-16-5-828 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn dermatomyositis characteristic eruptions are encountered in the skin and mucous membranes. These appearances must always be correlated with the remainder of the clinical picture, yet recognition of them often enables the observer to gain proper orientation in what seems to be an obscure case. Knowledge of these various manifestations provides a more substantial background for an evaluation of the differential diagnosis, therapy and prognosis of a disease that is far more common than the reports in the literature would indicate.1Throughout this communication stress will be laid on clinicopathologic correlations and special reference will be made to the differential...Bibliography1. KEIL H(a) : Dermatomyositis and systemic lupus erythematosus. 1. A clinical report of "transitional" cases, with a consideration of lead as a possible etiologic factor, Arch. Int. Med., 1940, lxvi, 109. (b) Dermatomyositis and systemic lupus erythematosus. 2. A comparative study of the essential clinicopathologic features, Arch. Int. Med., 1940, lxvi, 339. CrossrefGoogle Scholar2. PETGESPETGES GA: Poikilodermie, in nouvelle pratique dermatologique, Masson et Cie, Paris, 1936, vi, 114. Google Scholar3. V. LIVONIUS EW: Beitrag zur Kenntnis der Dermatomyositis, Berlin Thesis, 1938. Google Scholar4. KEIL H: Parapsoriasis en plaques disseminees and incipient mycosis fungoides, Arch. Dermat. and Syph., 1938, xxxvii, 465. CrossrefGoogle Scholar5. KEIL H: Conception of lupus erythematosus and its morphologic variants, with particular reference to "systemic" lupus erythematosus, Arch. Dermat. and Syph., 1937, xxxvi, 729. CrossrefGoogle Scholar6. KEIL H: Relation between "systemic" lupus erythematosus and a peculiar form of thrombocytopenic purpura, Brit. Jr. Dermat., 1937, xlix, 221. CrossrefGoogle Scholar7. CAUSADEALESHKOWSKA LS: Polymyosites rhumatismales de l'enfance, Paris méd., 1933, lxxxix, 469. Google Scholar8. PETGES PB: Poikilodermie et poikilodermatomyosite, Thèse de Bordeaux, 1929-1930. Google Scholar9. OPPENHEIM H: Zur Dermatomyositis, Berl. klin. Wchnschr., 1899, xxxvi, 805. Google Scholar10. OPPENHEIM H: Über die Polymyositis, Berl. klin. Wchnschr., 1903, xl, 381. Google Scholar11. GOTTRON H(a) : Hautveränderungen bei Dermatomyositis, VIII Congres International de Dermatologie et de Syphilographie, Aug. 5-9, 1930, Copenhagen, p. 826. (b) SCHUERMANN, H.: Zur Klinik und Pathogenese der Dermatomyositis (Polymyositis), Arch. f. Dermat. u. Syph., 1939, clxxviii, 414. (c) BRUUSGAARD, E.: Poikilodermie mit Polymyositis, Zentralbl. f. Haut. u. Geschlechtskr., 1933, xliii, 432. (d) FUHS, H.: Über Poikilodermatomyositis und ihre Stellung im System der Hautkrankheiten, Arch. f. Dermat. u. Syph., 1933, clxviii, 505. (e) ZOON, J. J.: Dermatomyositis und Poikilodermia Jacobi mit Muskelveränderungen, Arch. f. Dermat. u. Syph., 1934-35, clxxi, 223. Google Scholar12. MILIANRIMÉ G: Érythème scléro-oedémateux avec myopathie et myasthenie, Bull. Soc. franc. de dermat. et de syph., 1925, xxxii, 470. Google Scholar13. LORTAT-JACOB : discussion under reference 12. Google Scholar14. STRENG W: Ueber Polymyositis, Ztschr. f. klin. Med., 1904, liii, 162. Google Scholar15. PICK W: Dermatomyositis, Arch. f. Dermat. u. Syph., 1935, clxxiii, 302. CrossrefGoogle Scholar16. WARSZEWSKIRADZINSKI EHJM: Subacute polymyositis, Illinois Med. Jr., 1937, lxxi, 351. Google Scholar17. DOWLING GB: Dermatomyositis, St. Thomas Hosp. Rep., 1936, i, 150. Google Scholar18. SEMON H: Case of Poikilodermatomyositis, Brit. Jr. Dermat., 1937, xlix, 120. Google Scholar19. BAMBER G: Poikilodermatomyositis, Proc. Roy. Soc. Med. (Sect. Dermat.), 1936, xxix, 1635. Google Scholar20. URBACH E: Über Stauungs- und Stoffwechselkeratosen, Arch. f. Dermat. u. Syph., 1936, clxxiv, 400. CrossrefGoogle Scholar21. KEIL H: The rheumatic subcutaneous nodule and simulating lesions, Medicine, 1938, xvii, 261. CrossrefGoogle Scholar22. WEIDMANBESANCON FDJH: Erythema elevatum diutinum, Arch. Dermat. and Syph., 1929, xx, 593. CrossrefGoogle Scholar23. WEIDMAN FD: Personal communication kindly sent to the author, May 7, 1940. Dr. Weidman stated that he had no additional information on the further course of his second patient. Google Scholar24. GATELYKETRON JELW: Erythema elevatum diutinum (Weidman), Arch. Dermat. and Syph., 1939, xxxix, 901. Google Scholar25. URBACH E: Extracellular cholesterosis, in Handbuch d. Haut u. Geschlechtskr., 1932, xii, 320. Google Scholar26. TOWLE HP: Dermatomyositis, Arch. Dermat. and Syph., 1936, xxxiv, 298. Google Scholar27. MCCARTHY FP: Discussion of reference 26. Google Scholar28. : Dermatomyositis (a group of cases), Arch. Dermat. and Syph., 1937, xxxv, 984. Google Scholar29. HENDRYANDERSON AWTE: Dermatomyositis, Lancet, 1939, ii, 80. CrossrefGoogle Scholar30. O'LEARYWAISMAN PAM: Dermatomyositis; a study of forty cases, Arch. Dermat. and Syph., 1940, xli, 1001. CrossrefGoogle Scholar31. INGRAMSTEWART JTMJ: Dermatomyositis and Poikilodermia, Brit. Jr. Dermat., 1934, xlvi, 53. CrossrefGoogle Scholar32. BAILEY RH: Dermatomyositis complicated by calcinosis, Proc. Royal Soc. Med. (Sect. Study of Disease in Children), 1937-38, xxxi, 1155. Google Scholar33. SCHATZKI R: Beitrag zur Frage der Dermatomyositis (Polymyositis acuta), Berlin Thesis, 1926. Google Scholar34. CREVALD SV: Ein Fall von Polymyositis acuta, Ztschr. f. Kinderheilk., 1929, xlvii, 74; 1930, xlix, 357. CrossrefGoogle Scholar35. DOHI S: A case of Poikilodermia atrophicans vascularis, Zentralbl. f. Haut u. Geschlechtskr., 1929, xiv, 451. Google Scholar36. WOLFWILENS ASL: Dermatomyositis; a report of two cases with complete autopsy, Am. Jr. Path., 1936, xii, 235. Google Scholar37. ENGELHARDT W: Dermatomyositis (?); Poikilodermia vascularis atrophicans (?), Zentralbl. f. Haut u. Geschlechtskr., 1935-36, lii, 69. Google Scholar38. MEMMERT HP: Schleimhautveränderungen bei Dermatomyositis, Berlin Thesis, 1938. Google Scholar39. KEIL H: Erythema multiforme exsudativum (Hebra); a clinical entity associated with systemic features, ANN. INT. MED., 1940, xiv, 449. Google Scholar40. MARCUSWEINSTEIN IHJ(a) : Dermatomyositis; report of a case with a review of the literature, ANN. INT. MED., 1935-6, ix, 406. (b) GOTTSTEIN, E.: Über Polymyositis, Deutsch. Arch. f. klin. Med., 1907, xci, 198. (c) LANE, C. W.: Dermatomyositis, South. Med. Jr., 1938, xxxi, 287. Google Scholar41. STRUPPLER T: Zur Pathologie der multiplen nichteitrigen Myositis, Deutsch. Arch. f. klin. Med., 1900, lxviii, 407. Google Scholar42. MÜLLER R: Atrophoderma erythematodes reticularis (Poikiloderma atrophicans vascularis Jacobi), Arch. f. Dermat. u. Syph., 1911, cix, 501. CrossrefGoogle Scholar43. GLÜCK A(a) : "Dermatitis atrophicans reticularis" (Poikilodermia atrophicans vascularis Jacobi) mit mucinöser Degeneration der kollogenen Fasern, Arch. f. Dermat. u. Syph., 1913-14, cxviii, 113. (b) BETTMANN, S.: Uber die Poikilodermia atrophicans vascularis, Arch. f. Dermat. u. Syph., 1920, cxxix, 101. CrossrefGoogle Scholar44. STRÜMPELL A: Zur Kenntnis der primären acuten Polymyositis, Deutsch. Ztschr. f. Nervenheilk., 1891, i, 479. CrossrefGoogle Scholar45. BENSON JR: A case of dermatomyositis, Clin. Jr., 1904, xxiv, 315. Google Scholar46. SCHWARZ R: Beitrag zur Ätiologie der Polymyositis, Frankf. Ztschr. f. Path., 1921, xxv, 141. Google Scholar47. SLUCZEWSKI A: Über einen Fall von Dermatomyositis, Dermat. Ztschr., 1931, lxi, 390. CrossrefGoogle Scholar48. JACOBY GW: Subacute progressive polymyositis, Jr. Nerv. and Ment. Dis., 1888, xv, 697. CrossrefGoogle Scholar49. STEINFELD F: Zur Kenntnis der Dermatomyositis, Deutsch. med. Wchnschr., 1930, lxi, 697, 959. Google Scholar50. BEZECNY R: Dermatomyositis, Arch. f. Dermat. u. Syph., 1934-5, clxxi, 242. Google Scholar51. BRUCE GM: Retinitis in dermatomyositis, Trans. Am. Ophth. Soc., 1938, xxxvi, 282. Google Scholar52. SHELDONYOUNGDYKE JHFSC: Acute dermatomyositis associated with reticuloendotheliosis, Lancet, 1939, i, 82. CrossrefGoogle Scholar53. GREENAWAYLAMBIETHOMSONDAVIES TMCGEGS: Dermatomyositis, Brit. Jr. Dermat., 1937, xlix, 209. Google Scholar54. SCHMAUTZER J: Ueber Polymyositis acuta, Med. Klin., 1914, x, 281. Google Scholar55. LORENZ H: Die Muskelerkrankungen, in H. Nothnagel's Spec. Path. u. Therapie, Theil 3, 1898, xi, A. Hölder, Wien. Google Scholar56. POTAIN C: Morve chronique de forme anomale, Bull, et mém. Soc. méd. d. hôp. de Paris, 1876, xii, 314. Google Scholar57. KERL W(a) : Dermatomyositis, Zentralbl. f. Haut u. Geschlechtskr., 1936-7, lv, 179. (b) HAMMES, F.: Polymyositis chronica, ein Beitrag zum Symptomenbild derselben, Med. Klin., 1920, xvi, 872. Google Scholar58. RANDOLPH CC: Calcinosis universalis und dermatomyositis, Jr. Pediat., 1934, iv, 342. CrossrefGoogle Scholar59. O'LEARY PA(a) : Discussion in reference 28. (b) FRENCH, H.: An index of differential diagnosis of main symptoms, 4th Ed., 1928, p. 701, W. Wood & Co., N. Y. Google Scholar60. STEINITZSTEINFELD HF: Untersuchungen zum Kreatinstoffwechsel bei Dermatomyositis, Ztschr. f. d. ges. exper. Med., 1931, lxxix, 319. CrossrefGoogle Scholar61. BATTEN FE: Case of dermatomyositis in a child with pathological report, Brit. Jr. Child. Dis., 1912, ix, 247. Google Scholar62. SCHUERMANN H: Über Hauterscheinungen mit Beziehung zu Myxödem und basedowischer Krankheit, Arch. f. Dermat. u. Syph., 1937-8, clxxvi, 544. Google Scholar63. Case seen at the Newark Beth Israel Hospital, service of Dr. A. E. Parsonnet, through the courtesy of Drs. H. H. Goldberg and W. Antopol. Google Scholar64. GRZYBOWSKI M: Zur Kenntnis der Dermatomyositis, Arch. f. Dermat. u. Syph., 1936, clxxiv, 541. CrossrefGoogle Scholar65. OGILVIE WH: Three cases of myositis, Proc. Royal Soc. Med. (Section of Orthopedics), 1923-4, xvii, 7. Google Scholar66. CORNBLEETMURPHY TEL: A case for diagnosis (dermatomyositis), Arch. Dermat. and Syph., 1937, xxxvi, 647. Google Scholar67. KEIL H: Panniculitis-its place in nosology, Brit. Jr. Dermat., 1935, xlvii, 512. CrossrefGoogle Scholar68. VERON L(a) : Observation de myosite infectieuse aigue, Arch. de méd. et pharm. mil., 1888, xi, 481. (b) Buss: Ein Fall von acuter Dermatomyositis, Deutsch. med. Wchnschr., 1894, xx, 788. (c) VINCENT, H.: Polymyosite infectieuse aigue à récidives, Bull. et mém. Soc. méd. d. hôp. de Paris, 1903, xx, 633. (d) MÉRY, TERRIEN, and GÉNEVRIER: Polymyosite infectieuse aigue bénigne chez un enfant de neuf ans, ibid., 1904, xxi, 1115. (e) DRAGOEWA, N.: Polymyositis acuta und Trichinose, Berl. klin. Wchnschr., 1919, lvi, 316. Google Scholar69. PEEMÖLLER F(a) : Über Dermatomyositis, Deutsch. Ztschr. f. Nervenheilk., 1921, lxviii, 370. (b) OPPENHEIM, H.: Lehrbuch der Nervenkrankheiten, 7th Ed., 1923, vol. i, p. 840, S. Karger, Berlin. (c) KEIL, H.: Personal observations. (d) GOTTRON, H.: Dermat. Ztschr., 1931, lxi, 415. CrossrefGoogle Scholar70. FAHR T: Zur Frage der Polymyositis (Dermatomyositis), Arch. f. Dermat. u. Syph., 1921, cxxx, 1. CrossrefGoogle Scholar71. WELT-KAKELS S: A case of polymyositis with multiple lime deposits in a boy 5 years of age, Med. Rec., 1913, lxxxiii, 1052. Google Scholar72. SHELDONSHELDON JHW(a) : Dermatomyositis, Proc. Royal Soc. Med., 1931-32, xxv, 413. (b) KNIERIM, H.: Über akute, nicht eitrige Polymyositis, Deutsch. Ztschr. f. Nervenheilk., 1913, xlvii, 297. Google Scholar73. KEIL H: The rheumatic erythemas; a critical survey, ANN. INT. MED., 1938, xi, 2223. Google Scholar74. KARELITZWELT SSK(a) : Dermatomyositis, Am. Jr. Dis. Child., 1932, xliii, 1134. (b) EVANS, P. R.: Case of dermatomyositis, Brit. Jr. Dermat., 1937, xlix, 122. Google Scholar75. EHRMANN S: Ein neues Gefässymptom der Syphilis; seine Beziehung zur Cutis marmorata, zum grossmakulösem Syphilid und zur Spirochaeta pallida. 6th International Dermatologic Congress, New York, 1908, p. 763. Google Scholar76. KETRONBERNSTEIN LJC: Cutaneous manifestations of periarteritis nodosa, Arch. Dermat. and Syph., 1939, xl, 929. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Received for publication February 8, 1941. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe diagnosis and classification of amyopathic dermatomyositis: a historical review and assessment of existing criteriaOral Signs of Connective Tissue DiseaseOral lichen planus in a dermatomyositis patient that resolved after intravenous immunoglobulin therapySine Syndromes in Clinical Manifestation of DermatomyositisDermatomyositis: a contemporary review for oral health care providersOral manifestations as important symptoms for juvenile dermatomyositis early diagnosis: a case reportDermatomyositis and polymyositisOral lesions as an initial manifestation of dermatomyositis with occult malignancyEvaluation of oral manifestations and masticatory force in patients with polymyositis and dermatomyositisPeriorbital edema as the presenting sign of dermatomyositisDermatomyositis: an overview of recent progress with emphasis on dermatologic aspectsWould a new name hasten the acceptance of amyopathic dermatomyositis (dermatomyositis siné myositis) as a distinctive subset within the idiopathic inflammatory dermatomyopathies spectrum of clinical illness?Keratodermia blenorrhagica, arthritis, and polymyositis with cardiopulmonary complications.The Rheumatic Diseases in AdolescenceNeue Gesichtspunkte zur Pathogenese sogenannter KollagenosenDermatomyositisDermatomyositisVascular lesions in dermatomyositisViscero-cutaneous Collagenosis: A Study of the Intermediate Forms of Dermatomyositis, Scleroderma, and Disseminated Lupus ErythematosusOcular Manifestations of TrichinosisDERMATOMYOSITIS AS AN INDEX OF MALIGNANT NEOPLASM: REPORT OF A CASE AND REVIEW OF THE LITERATURE*MATTHEW J. BRUNNER, M.D., ROCCO V. LOBRAICO JR., M.D.DERMATOMYOSITIS: A REPORT OF A CASECutaneous MedicineDermatomyositis Associated with Metastasizing Bronchogenic CarcinomaSubacute and Acute Disseminated Lupus ErythematodesDERMATOMYOSITIS AND MALIGNANT TUMOUR 1 May 1942Volume 16, Issue 5Page: 828-871KeywordsDermatomyositisLupus erythematosusMucous membranes ePublished: 1 December 2008 Issue Published: 1 May 1942 PDF downloadLoading ...