STUDIES OF THE SERUM PROTEINS. III. A SYNDROME ASSOCIATED WITH ALPHA-3 GLOBULINEMIA
Authors: F W SUNDERMAN, F W SUNDERMAN
Journal: Annals of Internal Medicine (1959)

Article1 September 1959STUDIES OF THE SERUM PROTEINS. III. A SYNDROME ASSOCIATED WITH ALPHA-3 GLOBULINEMIAF. WILLIAM SUNDERMAN JR., M.D., F. WILLIAM SUNDERMAN, M.D., Ph.D., F.A.C.P.F. WILLIAM SUNDERMAN JR., M.D.Search for more papers by this author, F. WILLIAM SUNDERMAN, M.D., Ph.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-51-3-488 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptDuring the last five years the authors have studied the electrophoretic patterns of the serum proteins from approximately 2,000 patients who suffered from the wide variety of pathologic conditions encountered in general hospital practice. Throughout this period, interest has been directed to the clinical significance of protein moieties with abnormal electrophoretic mobilities, and within the last year, especial attention has been focused upon a component which migrates between alpha-2 and beta globulins.Since there is confusion in the literature regarding the designation of abnormal serum proteins migrating between alpha-2 and beta globulins, a chronologic resumé of pertinent nomenclature is presented...Bibliography1. Abdel-WahabAdjutantisLaurence EGDJ: Borate buffer as a medium for the iontophoresis of human plasma proteins, Biochem. J. 60: xiii, 1955. MedlineGoogle Scholar2. AdamsAllingLawrence WSELJS: Multiple myeloma: its clinical and laboratory diagnosis with emphasis on electrophoretic abnormalities, Am. J. Med. 6: 141-161, 1949. CrossrefMedlineGoogle Scholar3. 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Author, Article, and Disclosure InformationAffiliations: Philadelphia, Pennsylvania*Received for publication February 20, 1959.From the Division of Metabolic Research, Jefferson Medical College, Philadelphia, Pennsylvania.Presented before the Regional Meeting of the American College of Physicians, Philadelphia, January 23, 1959.These investigations were supported in part by contract of Jefferson Medical College with the Atomic Energy Commission.†Present address: Chemistry Branch, U. S. Naval Medical School, Bethesda 14, Maryland.Requests for reprints should be addressed to F. William Sunderman, M.D., Jefferson Medical College, 1025 Walnut Street, Philadelphia 7, Pennsylvania. 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