ADRENOCORTICOTROPIC HORMONE AND ADRENAL STEROIDS IN THE MANAGEMENT OF INFECTIOUS DISEASES
Authors: W W SPINK
Journal: Annals of Internal Medicine (1955)

Article1 October 1955ADRENOCORTICOTROPIC HORMONE AND ADRENAL STEROIDS IN THE MANAGEMENT OF INFECTIOUS DISEASESWESLEY W. SPINK, M.D., F.A.C.P.WESLEY W. SPINK, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-43-4-685 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn their initial reports upon the effects of corticotropin and cortisone in patients having rheumatoid arthritis or rheumatic fever, Hench and his associates1, 2emphasized two manifestations: inflammation of the tissues was subdued, and the patients experienced a remarkable sense of well-being. Soon thereafter, extensive observations were made by others3, 4, 5in human subjects having a variety of infections, and in experimentally infected animals. It was demonstrated in patients with pneumococcal pneumonia that the administration of ACTH caused a crisis and striking improvement, although pneumococci persisted in the tissues for many days.6On the other hand, it was also...Bibliography1. HenchKendallSlocumbPolley PSECCHHF: The effect of a hormone of the adrenal cortex (17-hydroxy-11-dehydrocorticosterone: Compound E) and of pituitary adrenocorticotropic hormone on rheumatoid arthritis; preliminary report, Proc. Staff Meet., Mayo Clin. 24: 181, 1949. MedlineGoogle Scholar2. HenchSlocumbBarnesSmithPolleyKendall PSCHARHLHFEC: The effects of the adrenal cortical hormone 17-hydroxy-11-dehydrocorticosterone (Compound E) on the acute phase of rheumatic fever: preliminary report, Proc. Staff Meet., Mayo Clin. 24: 277, 1949. MedlineGoogle Scholar3. Thomas L: Infectious diseases (the effects of cortisone and adrenocorticotropic hormone on infection), Ann. Rev. Med. 3: 1, 1952. CrossrefMedlineGoogle Scholar4. 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Author, Article, and Disclosure InformationAffiliations: Minneapolis, Minnesota*From the Symposium on ACTH and Cortisone, presented at the Thirty-sixth Annual Session of the American College of Physicians, Philadelphia, Pennsylvania, April 28, 1955.From the Department of Medicine, University of Minnesota Hospitals and Medical School, Minneapolis. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byCorticotropin and Corticosteroids in Human Viral InfectionsShock in infectious diseasesSteroids in InfectionADRENOCORTICAL STEROIDS IN THE MANAGEMENT OF SELECTED PATIENTS WITH INFECTIOUS DISEASES*WESLEY W. SPINK, M.D., F.A.C.P.Continued Observations on the Role of Steroid Therapy in Tuberculosis*Herz- und Kreislaufstörungen bei InfektionskrankheitenHerz- und Kreislaufstörungen bei InfektionskrankheitenRHEUMATISM AND ARTHRITIS: REVIEW OF AMERICAN AND ENGLISH LITERATURE OF RECENT YEARS (TWELFTH RHEUMATISM REVIEW)* Part IICHARLEY J. SMYTH, M.D., F.A.C.P., JOSEPH J. BUNIM, M.D., F.A.C.P., WILLIAM S. CLARK, M.D., F.A.C.P., DARRELL C. CRAIN, M.D., F.A.C.P., FELIX E. DEMARTINI, M.D., IVAN F. DUFF, M.D., F.A.C.P., EPHRAIM P. ENGLEMAN, M.D., F.A.C.P., DONALD C. GRAHAM, M.D., F.R.C.P. (C), MAX M. MONTGOMERY, M.D., F.A.C.P., BERNARD M. NORCROSS, M.D., F.A.C.P., HOWARD F. POLLEY, MARIAN W. ROPES, M.D., F.A.C.P., EDWARD F. ROSENBERG, M.D., F.A.C.P.MUMPS MYOCARDITIS: CASE REPORT WITH REVIEW OF THE LITERATURE*GLENN E. HORTON, M.D.EFFECTS OF CORTISONE AND ACTH IN MUMPS MENINGO-ENCEPHALITIS*JOHN K. SPITZNAGELACTH and adrenal steroids in the treatment of pneumococcal meningitis in adultsCurrent Concepts on the Management of ShockACTH and Adrenocorticosteroids as Therapeutic Adjuncts in Infectious DiseasesCancer of the Colon and Rectum: A Consideration of Mortality FactorsCORTICOTROPIN AND ADRENAL STEROIDS AS ADJUNCTS TO THE TREATMENT OF TUBERCULOUS MENINGITIS*J. RICHARD JOHNSON, M.D., NANCY E. FURSTENBERG, M.D., ROY PATTERSON, M.D., HENRY K. SCHOCH, M.D., WINTHROP N. DAVEY, M.D. 1 October 1955Volume 43, Issue 4Page: 685-701KeywordsAdrenocorticotropic hormoneHormonesInflammationOrchitisPneumoniaRheumatic feverRheumatoid arthritisSteroidsTuberculosisTyphoid ePublished: 1 December 2008 Issue Published: 1 October 1955 PDF downloadLoading ...