MINERALOCORTICOID-LIKE DISTURBANCE ASSOCIATED WITH ADRENAL METASTASES FROM A BRONCHOGENIC CARCINOMA
Authors: W B SPAULDING, W A OILLE, A G GORNALL
Journal: Annals of Internal Medicine (1955)

Case Reports1 February 1955MINERALOCORTICOID-LIKE DISTURBANCE ASSOCIATED WITH ADRENAL METASTASES FROM A BRONCHOGENIC CARCINOMAW. B. SPAULDING, M.D., F.R.C.P. (C.), W. A. OILLE, M.D., F.R.C.P. (C.), A. G. GORNALL, Ph.D.W. B. SPAULDING, M.D., F.R.C.P. (C.), W. A. OILLE, M.D., F.R.C.P. (C.), A. G. GORNALL, Ph.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-42-2-444 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptA few patients with Cushing's syndrome have severe electrolyte disturbances in the form of hypokalemia, hypochloremia, alkalosis and hyperglycemia.1, 2 We are reporting a patient who lacked most of the features of Cushing's syndrome but in whom this type of biochemical disorder prompted an investigation of the adrenals and revealed an unusual group of findings. The urinary corticoid output was increased. Pyelography showed an adrenal tumor, but the tumor removed surgically proved to be metastatic and autopsy showed the tumor to have originated in the lung.CASE REPORTThe patient was a 56 year old office worker who had been...Bibliography1. McQuarrieJohnsonZiegler IRMMR: Plasma electrolyte disturbance in patient with hypercorticoadrenal syndrome contrasted with that found in Addison's disease, Endocrinology 21: 762, 1937. CrossrefGoogle Scholar2. WillsonPowerKepler DMMHEJ: Alkalosis and low plasma potassium in a case of Cushing's syndrome: a metabolic study, J. Clin. Investigation 19: 701, 1940. CrossrefMedlineGoogle Scholar3. M. R. C. Committee on clinical endocrinology: proposed standard method of 17-ketosteroid determination, Lancet 2: 585, 1951. MedlineGoogle Scholar4. GornallMacdonald AGMP: Quantitative determination of the steroid hormones with 2, 4-dinitrophenylhydrazine, J. Biol. Chem. 201: 279, 1953. CrossrefMedlineGoogle Scholar5. 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Author, Article, and Disclosure InformationAffiliations: Toronto, Ontario*Received for publication March 31, 1954.From the Medical Service, Toronto General Hospital, and the Department of Pathological Chemistry, University of Toronto.†John and Mary R. Markle Scholar in Medical Science. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byCushing's syndrome associated with carcinoma of the bronchusPrimary aldosteronism by carcinoma of the adrenal cortexTreatment of bronchogenic carcinomaPrimary Aldosteronism Due to an Adrenal CarcinomaMILTON G. CRANE, M.D., F.A.C.P., JOHN J. 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SHNIDER, M.D.CUSHING'S SYNDROME ASSOCIATED WITH ADENOCARCINOMA OF THE OVARYTHE SYNDROME OF MINERALOCORTICOID EXCESSCushing's syndrome and bronchogenic carcinomaObservations on a case of primary aldosteronismPotassium deficiency of renal and adrenal origin 1 February 1955Volume 42, Issue 2Page: 444-451KeywordsAdrenal tumorsAutopsyLungsMedical servicesPyelography Issue Published: 1 February 1955 PDF downloadLoading ...