Sugar, Fat, and the Pill
Authors: KENNETH A. WOEBER
Journal: Annals of Internal Medicine (1967)

Editorial Notes1 February 1967Sugar, Fat, and the PillKENNETH A. WOEBER, M.D., M.R.C.P.(E.), RONALD A. ARKY, M.D.KENNETH A. WOEBER, M.D., M.R.C.P.(E.)Search for more papers by this author, RONALD A. ARKY, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-66-2-446 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptEstrogens and progestagens given in combination are finding wide clinical application as oral contraceptive agents by virtue of their ability to suppress ovulation. These agents mimic pregnancy in some of their effects; for example, they elevate the plasma levels of protein-bound iodine (1) and cortisol (2) without producing clinical evidence of thyroidal or adrenocortical overactivity. Pregnancy has a diabetogenic influence, and attention has previously been drawn to an impairment of glucose tolerance in women taking oral contraceptive agents (3, 4). This observation has now been extended by Wynn and Doar (5) to a group of 105 women who had taken...References1. HOLLANDERGARCIASTURGISSELENKOW CSAMSNHA: Effect of an ovulatory suppressant on the serum protein-bound iodine and the red-cell uptake of radio-active triiodothyronine. New Eng. J. Med. 269: 501, 1963. CrossrefMedlineGoogle Scholar2. METCALFBEAVEN MGDW: Plasma-corticosteroid levels in women receiving oral contraceptive tablets. Lancet 2: 1095, 1963. CrossrefMedlineGoogle Scholar3. GERSHBERGJAVIERHULSE HZM: Glucose tolerance in women receiving an ovulatory suppressant. Diabetes 13: 378, 1964. CrossrefMedlineGoogle Scholar4. PETERSONSTEELCOYNE WFMWRV: Analysis of the effect of ovulatory suppressants on glucose tolerance. Amer. J. Obstet. Gynec. 95: 484, 1966. CrossrefMedlineGoogle Scholar5. WYNNDOAR VJW: Some effects of oral contraceptives on carbohydrate metabolism. Lancet 2: 715, 1966. CrossrefMedlineGoogle Scholar6. HENNESWAJCHENBERGFAJANSCONN ARBLSSJW: The effect of adrenal steroids on blood levels of pyruvic and alpha-ketoglutaric acids in normal subjects. Metabolism 6: 339, 1957. MedlineGoogle Scholar7. WYNNDOARMILLS VJWGL: Some effects of oral contraceptives on serum-lipid and lipoprotein levels. Lancet 2: 720, 1966. CrossrefMedlineGoogle Scholar8. KALKHOFFSCHALCHWALKERBECKKIPNISDAUGHADAY RDSJLPDMWH: Diabetogenic factors associated with pregnancy. Trans. Ass. Amer. Physicians 77: 270, 1964. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Thorndike Memorial Laboratory Boston City Hospital Boston, Mass. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByMedical Aspects of Oral ContraceptivesNEIL J. ELGEE, M.D.Ischemic Heart Disease in Young Adults Metabolic and Angiographic Diagnosis and the Prevalence of Type IV HyperlipoproteinemiaDAVID H. BLANKENHORN, M.D., F.A.C.P., H. P. CHIN, PH.D., FRANCIS Y. K. LAU, M.D., F.A.C.P.Treatment of Breast Cancer with Medroxyprogesterone AcetateFRANCO M. MUGGIA, M.D., PETER A. CASSILETH, M.D., MANUEL OCHOA JR., M.D., FREDERICK A. FLATOW, M.D., ALFRED GELLHORN, M.D., F.A.C.P., GEORGE A. HYMAN, M.D., F.A.C.P. 1 February 1967Volume 66, Issue 2Page: 446-447KeywordsBlood plasmaCortisolEstrogensFatsGlucose toleranceOral contraceptive therapyOvulationPlasma proteinsPregnancyThyroid Issue Published: 1 February 1967 PDF DownloadLoading ...