CLINICAL OBSERVATIONS IN 100 CASES OF INFECTIOUS MONONUCLEOSIS AND THE RESULTS OF TREATMENT WITH PENICILLIN AND AUREOMYCIN
Authors: A L SCHULTZ, W H HALL
Journal: Annals of Internal Medicine (1952)

Article1 June 1952CLINICAL OBSERVATIONS IN 100 CASES OF INFECTIOUS MONONUCLEOSIS AND THE RESULTS OF TREATMENT WITH PENICILLIN AND AUREOMYCINALVIN L. SCHULTZ, M.D., WENDELL H. HALL, M.D.ALVIN L. SCHULTZ, M.D.Search for more papers by this author, WENDELL H. HALL, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-36-6-1498 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn the past decade, increasing attention has been centered on the many unusual findings in infectious mononucleosis. The diagnosis is often difficult, particularly when pneumonitis, anemia or electrocardiographic or neurologic abnormalities are present. The clinician is frequently confronted with this disease, and awareness of its protean manifestations is necessary to avoid confusion in diagnosis. The present series of cases, seen in a large general hospital, exhibits almost all the features of infectious mononucleosis which may be encountered. In addition, the results of treatment are described, an aspect neglected until recently in the medical literature.CLINICAL MATERIALOne hundred cases of...Bibliography1. DowneyMcKinlay HCA: Acute lymphadenosis compared with acute leukemia, Arch. Int. Med. 32: 88, 1923. CrossrefGoogle Scholar2. Schleicher EM: Reticulum hyperplasia and proliferation of lymphoid cells in the bone marrow in infectious mononucleosis, Acta Haematol. 2: 243, 1949. CrossrefGoogle Scholar3. HovdeSundberg RD: Granulomatous lesions in the bone marrow in infectious mononucleosis, Blood 5: 209, 1950. CrossrefMedlineGoogle Scholar4. Evans AS: Further experimental attempts to transmit infectious mononucleosis to man, J. Clin. Investigation 29: 508, 1950. CrossrefMedlineGoogle Scholar5. EvansRobinton ASED: An epidemiologic study of infectious mononucleosis in a New England college, New England J. Med. 242: 492, 1950. CrossrefGoogle Scholar6. Abrams H: Infectious mononucleosis with intense jaundice of long duration, New England J. Med. 238: 295, 1948. CrossrefMedlineGoogle Scholar7. DeMarshAlt QH: Hepatitis without jaundice in infectious mononucleosis, J. Lab. and Clin. Med. 32: 320, 1947. MedlineGoogle Scholar8. BrownSimsClifford JJJ: Hepatic function in infectious mononucleosis, J. Lab. and Clin. Med. 32: 1523, 1947. Google Scholar9. Gall EA: Serum phosphatase and other tests of liver function in infectious mononucleosis, Am. J. Clin. Path. 17: 529, 1947. CrossrefMedlineGoogle Scholar10. BerkShayRitterSiplet JDHJH: Infectious mononucleosis and infectious hepatitis, studies bearing on certain resemblances and differences, Gastroenterology 11: 658, 1948. MedlineGoogle Scholar11. Evans A: Liver involvement in infectious mononucleosis, J. Clin. Investigation 27: 106, 1948. CrossrefMedlineGoogle Scholar12. Peterson RE: Hepatic dysfunction in infectious mononucleosis; with review of the literature, J. Lab. and Clin. Med. 33: 1258, 1948. MedlineGoogle Scholar13. CusterSmith RPEB: The pathology of infectious mononucleosis, Blood 3: 830, 1948. CrossrefMedlineGoogle Scholar14. WechslerRosenblumSills HAC: Infectious mononucleosis, report of an epidemic in an army post, Ann. Int. Med. 25: 113-133, 236-265, 1946. LinkGoogle Scholar15. ReadHelwig JF: Infectious mononucleosis, an analysis of 300 cases, Arch. Int. Med. 75: 376, 1945. CrossrefGoogle Scholar16. WilsonWardGray SCL: Infectious mononucleosis and hemolytic anemia in a Negro, Blood 4: 189, 1949. CrossrefMedlineGoogle Scholar17. AppelmanMorrison DM: Concomitant infectious mononucleosis and hemolytic icterus, Blood 4: 186, 1949. CrossrefMedlineGoogle Scholar18. Bennike T: Penicillin treatment of infectious mononucleosis, Arch. Int. Med. 87: 187, 1951. CrossrefGoogle Scholar19. Gruskin BJ: Aureomycin in acute infectious mononucleosis, Ann. Int. Med. 31: 678, 1949. LinkGoogle Scholar20. Lyons HA: Aureomycin in the treatment of infectious mononucleosis, U. S. Nav. M. Bull. 49: 1076, 1949. MedlineGoogle Scholar21. LyonsHard HAEM: The effect of aureomycin therapy in infectious mononucleosis, Bull. New York Acad. Med. 26: 279, 1950. Google Scholar22. CarterSydenstricker CHVP: Aureomycin in the treatment of infectious mononucleosis, Am. J. Med. 10: 309, 1951. CrossrefMedlineGoogle Scholar23. SeifertChandlerVan Winkle MHVLW: Aureomycin in infectious mononucleosis, J. A. M. A. 142: 1133, 1950. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Minneapolis, Minnesota*Received for publication October 15, 1951.From the Veterans Administration Hospital and the Department of Medicine, The Medical School, University of Minnesota, Minneapolis.Reviewed in the Veterans Administration and published with the approval of the Chief Medical Director. The statements and conclusions published by the authors are the result of their own study and do not necessarily reflect the opinion or policy of the Veterans Administration. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byInfectious Mononucleosis Epidemiology and PathogenesisStreptococcal Pharyngitis in Infectious MononucleosisA Study of Beta Hemolytic Streptococcal Pharyngitis in Patients with Infectious MononucleosisClinical and laboratory evaluation of elderly patients with heterophil-antibody positive infectious mononucleosisDie infektiöse Mononucleose�ber eine t�dliche Lungenkomplikation der infekti�sen MononucleoseBiochemical studies on hepatic involvement in infectious mononucleosisTreatment of Infectious MononucleosisHAROLD R. SCHUMACHER, WILLIAM A. JACOBSON, CARL R. BEMILLER, M.D.Health in Colleges and UniversitiesSerum enzymes in diseaseSerum alkaline phosphatase activity in hepatitis of infectious mononucleosisZur Beteiligung der Leber bei der infektiösen MononucleoseSerum alkaline phosphatase activity in diseases of the skeletal and hepatobiliary systemsInfectious mononucleosis hepatitisPROBABLE INFECTIOUS MONONUCLEOSIS WITHOUT POSITIVE HETEROPHIL AGGLUTINATION TESTS*SIDNEY LEIBOWITZ, M.D., F.A.C.P.Beiträge zum Problem der Infektiösen Mononukleose 1 June 1952Volume 36, Issue 6Page: 1498-1512KeywordsAnemiaElectrocardiographyHospital medicinePenicillinPneumonitis ePublished: 1 December 2008 Issue Published: 1 June 1952 PDF downloadLoading ...