The Response of Stroke Patients to Very Small Doses of Parenteral Reserpine
Authors: STANLEY C. LEONBERG
Journal: Annals of Internal Medicine (1964)

Article1 May 1964The Response of Stroke Patients to Very Small Doses of Parenteral ReserpineSTANLEY C. LEONBERG JR., M.D., JOSEPH B. GREEN, M.D., FRANK A. ELLIOTT, M.D.STANLEY C. LEONBERG JR., M.D., JOSEPH B. GREEN, M.D., FRANK A. ELLIOTT, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-60-5-866 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe parenteral administration of reserpine is advocated by many authorities for the treatment of acute hypertensive crises. According to Moyer and Brest (1), parenterally administered reserpine "combines potency, ease of administration and safety." In their experience, excessive hypotension is relatively rare with such therapy, and they indicate that vasopressor agents are usually effective in correcting complications. Hoobler and Blaquier (2) recommend reserpine, finding it especially effective in moderating hypertensive crises, and add that acute shock does not result from an over-dosage with this drug.The recommended dosages of reserpine for this purpose range, generally, from 1.0 to 5.0 mg intramuscularly or...References1. MOYERBREST JA: Treatment of hypertensive emergencies, in Hypertension, Recent Advances (Second Hahnemann Symposium on Hypertension), edited by MOYER, J., and BREST A., Lea & Febiger, Philadelphia, 1961, p. 516. Google Scholar2. HOOBLERBLAQUIER SP: Therapeutic use of hydralazine (Apresoline) and rauwolfia compounds in hypertension, in Hypertension (First Hahnemann Symposium on Hypertension), edited by MOYER, J., W. B. Saunders Company, Philadelphia, 1959, p. 384. Google Scholar3. GIFFORD R: Treatment of hypertensive emergencies associated with essential hypertension, Ibid. (First Hahnemann Symposium on Hypertension), pp. 615 and 681. Google Scholar4. 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KLEINERORTEN IJ: Biochemistry, 6th Ed., C. V. Mosby Co., St. Louis, 1962, p. 478. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: STANLEY C. LEONBERGJR., M.D.; JOSEPH B. GREEN, M.D.; FRANK A. ELLIOTT, M.D.Affiliations: Philadelphia, PennsylvaniaFrom the Neurology Unit, The Pennsylvania Hospital, Philadelphia, Pennsylvania.This work was supported by a grant from The John A. Hartford Foundation.Requests for reprints should be addressed to Stanley C. Leonberg, Jr., M.D., Pennsylvania Hospital, 8th and Spruce Streets, Philadelphia 7, Pennsylvania. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byTreatment of Hypertensive CrisisBehandlung der hypertensiven KriseHypertensive emergenciesDrugs in the Management of Hypertensive Emergencies in ChildrenHypertensive EmergenciesEffectiveness of Small, Increasing Doses of Intramuscular Reserpine in HypertensionThe Treatment of Brain Ischemia With Vasopressor DrugsReport of the Panels on Cardiovascular Drugs from the Drug Efficacy StudyManagement of hypertensive crisis 1 May 1964Volume 60, Issue 5 Page: 866-870 Keywords Drugs Hypertension Hypotension Neurology Ointments Reserpine Safety Shock Stroke Vasopressors ePublished: 1 December 2008 Issue Published: 1 May 1964 PDF downloadLoading ...