THE THERAPEUTIC USE OF VENESECTION IN POLYCYTHEMIA
Authors: D. J. Stephens, Nolan L. Kaltreider
Journal: Annals of Internal Medicine (1937)

Article1 April 1937THE THERAPEUTIC USE OF VENESECTION IN POLYCYTHEMIAD. J. STEPHENS, M.D., NOLAN L. KALTREIDER, M.D.D. J. STEPHENS, M.D.Search for more papers by this author, NOLAN L. KALTREIDER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-10-10-1565 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlthough venesection has been used for many years as an emergency measure in erythremia, its general use as a therapeutic agent in this disease has been considered contraindicated on the grounds that reduction of the blood level by this means would act as a further stimulus to erythrocyte production.1Recent investigations, however, have indicated that this assumption may be unwarranted. Falconer2has shown that the repeated removal of from 200 to 600 c.c. of blood at intervals of from a few days to three weeks did not increase the reticulocyte percentage above normal limits. Reimann and Breuer3have studied the...Bibliography1. HARROP GA(a) : Polycythemia, Medicine, 1928, vii, 291. (b) PARK, G. T., and CRAVER, L. F.: The radiation therapy of polycythemia vera, Am. Jr. Med. Sci., 1930, clxxx, 609. (c) FORKNER, C. E., SCOTT, T. F., and WU, S. C.: Treatment of polycythemia vera with solution of potassium arsenite, Arch. Int. Med., 1933, li, 616. Google Scholar2. FALCONER EH: Treatment of polycythemia. The reticulocyte response to venesection, phenylhydrazine and radiation, ANN. INT. MED., 1933, vii, 172. LinkGoogle Scholar3. REIMANNBREUER FA: Die Aderlassbehandlung der Erythrämie, Ztschr. f. klin. Med., 1935, cxxviii, 238. Google Scholar4. GIFFINCONNER HZHM: The untoward effects of treatment by phenylhydrazine hydrochloride, Jr. Am. Med. Assoc., 1929, xcii, 1505. 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H., and BODANSKY, M.: The treatment of polycythemia vera, Jr. Am. Med. Assoc., 1933, ci, 495. (c) GIFFIN, H. Z., and ALLEN, E. V.: Control and complete remission of polycythemia vera following prolonged administration of phenylhydrazine hydrochloride, Am. Jr. Med. Sci., 1933, clxxxv, 1. CrossrefGoogle Scholar11. (a) ALLEN E. V. BARKER N. W. : Experiments with phenylhydrazine. III. Pathologic anatomy, ANN. INT. MED., 1928, i, 683. (b) BASSETT, S. H., KILLIP, T., and MCCANN, W. S.: Mineral exchanges of man. III. Mineral metabolism during treatment of a case of polycythemia vera, Jr. Clin. Invest., 1931, x, 771. LinkGoogle Scholar12. HUEPER WC: Pathologic studies on the organic effects of various hydrazine derivatives, Jr. Indust. Hyg. and Toxicology, 1936, xviii, 17. Google Scholar13. (a) MORRIS R. S. : Erythremia, a therapeutic suggestion, Jr. Am. Med. Assoc., 1933, ci, 200. (b) BRIGGS, J. F., and OERTING, H.: Influence of gastric lavage on familial and non-familial erythremia, Minnesota Med., 1935, xviii, 499. CrossrefGoogle Scholar14. HEATH CW: Oral administration of iron in hypochromic anemia, Arch. Int. Med., 1933, li, 459. CrossrefGoogle Scholar15. HURTADO A: Studies at high altitude. Blood observations on the Indian natives of the Peruvian Andes, Am. Jr. Physiol., 1932, c, 487. CrossrefGoogle Scholar16. HEATH CW: The volume and hemoglobin content of the red blood corpuscles in the light of recent knowledge of anemia, New Eng. Jr. Med., 1933, ccix, 173. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Rochester, New York*Received for publication January 28, 1937.From the University of Rochester School of Medicine and Dentistry and the Medical Clinics of the Strong Memorial and Rochester Municipal Hospitals, Rochester, New York. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPolycythemia Vera: Scientific Advances and Current PracticePolycythemia vera: myths, mechanisms, and managementTHE OPTIMAL MANAGEMENT OF POLYCYTHAEMIA VERA4 Treatment of polycythaemia vera and essential thrombocythaemiaPolycythemiaErythrocythemiaPolycythaemia veraPOLYCYTHÆMIA VERAThe treatment of polycythemia veraBehandlung der Polycythaemia vera mit DaraprimTreatment of Polycythemia Vera with large Venesections and Plasma Transfusions.Die Erkrankungen des erythrocytären Systems 1 April 1937Volume 10, Issue 10Page: 1565-1581KeywordsBloodDentistryHospital medicinePhlebotomyPolycythemiaPolycythemia veraReticulocytes ePublished: 1 December 2008 Issue Published: 1 April 1937 PDF downloadLoading ...