STUDIES ON THE INCREASED METABOLISM IN HYPERTHYROIDISM
Authors: E. Cowles Andrus, Donald Mceachern
Journal: Annals of Internal Medicine (1935)

Article1 November 1935STUDIES ON THE INCREASED METABOLISM IN HYPERTHYROIDISME. COWLES ANDRUS, M.D., F.A.C.P., DONALD MCEACHERN, M.D.E. COWLES ANDRUS, M.D., F.A.C.P., DONALD MCEACHERN, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-9-5-579 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe metabolic phenomena characteristic of hyperthyroidism are common to both the clinical and the experimental forms. In the clinical disease, these changes may only be observed en masse. They may be measured only as they are reflected in the total displacement of certain equilibria such as the oxygen consumption, carbon dioxide production, glucose tolerance, nitrogen balance, and the creatine metabolism.Experimental hyperthyroidism may be produced in animals to any desired degree by the administration of thyroid extract or by the injection of thyroxine. Under these circumstances it is possible to analyze the metabolic alterations and to subject various elements thereof...Bibliography1. RIMLWOLFF OHG: Zur Frage des Angriffspunktes der stoffwechselsteigernden Schilddrusenwirkung, Arch. f. exper. Path. u. Pharmakol., 1930, clvii, 178-192. CrossrefGoogle Scholar2. DAVISDACOSTAHASTINGS JEEAB: Effect of thyroxine on the tissue metabolism of the excised frog heart, Am. Jr. Physiol., 1934, cx, 187-190. CrossrefGoogle Scholar3. LEWISMCEACHERN JKD: Persistence of an accelerated rate in the isolated hearts of thyrotoxic rabbits: response to iodides, thyroxine and epinephrine, Bull. Johns Hopkins Hosp., 1931, xlviii, 228-241. Google Scholar4. REISSHOCKWALDDRUCKREY MAH: Thyreotroper Wirkstoff des Hypophysenvorderlappens und Gewebsstoffwechsel, Med. Klin., 1933, xxix, 1112-1113. Google Scholar5. MEAKINS JC: Modern muscle physiology and circulatory failure, ANN. INT. MED., 1932, vi, 506-513. LinkGoogle Scholar6. HAFFNER F: Pharmakologische Untersuchungen mit einem deutschen Thyroxin, Klin. Wchnschr., 1927, vi, 1932-1935. CrossrefGoogle Scholar7. ANDRUSMCEACHERN ECD: An investigation of the lactic acid metabolism in hyperthyroidism, Trans. Assoc. Am. Phys., 1934, xlix, 65-75. Google Scholar8. MCEACHERN D: The metabolism of isolated surviving tissues from animals rendered hyperthyroid with thyroxine, Bull. Johns Hopkins Hosp., 1935, lvi, 145. Google Scholar9. ALT HL: Über die Atmungshemmung durch Blausäure, Biochem. Ztschr., 1930, ccxxi, 498-501. Google Scholar10. WARBURG O: Über Nicht-Hemmung der Zellatmung durch Blausäure, Biochem. Ztschr., 1931, ccxxxi, 493-497. Google Scholar11. REID A: Das sauerstoffübertragende Ferment der Atmung, Fortschr. d. Med., 1932, l, 133-134. Google Scholar12. DYEWAGGENER JARA: Studies in tissue respiration and endocrine function. I. The influence of thyroidectomy on the iodophenol oxidase content of animal tissues, Am. Jr. Physiol., 1928, lxxxv, 1-13. Google Scholar13. MARINEROSEN DSH: The exophthalmos of Graves' disease. Its experimental production and significance, Am. Jr. Med. Sci., 1934, clxxxviii, 565-571. CrossrefGoogle Scholar14. BLUMGARTLEVINEBERLIN HLSADD: Congestive heart failure and angina pectoris. The therapeutic effect of thyroidectomy on patients without clinical or pathologic evidence of thyroid toxicity, Arch. Int. Med., 1933, li, 866-877. CrossrefGoogle Scholar15. MEANSLERMAN JHJ: The action of iodine in thyrotoxicosis, Jr. Am. Med. Assoc., 1935, civ, 969-972. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Baltimore, Maryland*Read at the Philadelphia meeting of the American College of Physicians, April 29, 1935.From the Cardiographic Laboratory, Department of Medicine, Johns Hopkins University and Hospital.†Under a Fellowship of the National Research Council, Washington, D. C., and a Jacques Loeb Fellowship and a Bingham Fellowship of the Johns Hopkins Hospital and University, Baltimore. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byHerz und Kreislauf bei Störungen der SchilddrüsenfunktionHerz und Kreislauf bei Störungen der SchilddrüsenfunktionThe Thyroid and the CirculationPrüfung der endokrinen FunktionenDie normale und pathologische Physiologie der SchilddrüsePreoperative and postoperative treatment of the toxic thyroid 1 November 1935Volume 9, Issue 5Page: 579-585KeywordsCreatineFellowshipsGlucose metabolismGlucose toleranceHospital medicineHyperthyroidismOxygen consumptionResearch laboratoriesThyroidThyroxine ePublished: 1 December 2008 Issue Published: 1 November 1935 PDF downloadLoading ...