Androgens and Hepatocellular Carcinoma in an Athlete
Authors: WYLIE L. OVERLY
Journal: Annals of Internal Medicine (1984)

Letters and Corrections1 January 1984Androgens and Hepatocellular Carcinoma in an AthleteWYLIE L. OVERLY, M.D., JOSEPH A. DANKOFF, B.S., BARBARA K. WANG, M.D., USHA D. SINGH, M.D.WYLIE L. OVERLY, M.D., JOSEPH A. DANKOFF, B.S., BARBARA K. WANG, M.D., USHA D. SINGH, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-100-1-158_3 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: An association between primary hepatic tumors and androgen therapy was first noted in 1965 (1). In a recent review of the literature, 33 cases of patients with androgen-associated hepatic tumors were reported (2); 14 of these patients had received androgens as therapy for Fanconi's anemia, and 19 patients, for various other, potentially androgen-responsive illnesses. We have recently cared for a young man who developed a primary hepatic malignancy after taking androgens to increase his skeletal muscle mass. This patient represents the first reported case of such a malignancy in an otherwise healthy athlete taking androgens for this...References1. RECANTLACY LP. Fanconi's anaemia and hepatic cirrhosis. Am J Med. 1965;39:466-75. Google Scholar2. WESTABYWILLIAMS DR. Androgen and anabolic steroid related liver tumours. In: DAVIS M, TEDGER JM, WILLIAMS R, eds. Drug Reactions and the Liver. London: Pitman Medical; 1981:284-9. Google Scholar3. SWEENEYEVANS ED. Hepatic lesions in patients treated with synthetic anabolic steroids. J Clin Pathol. 1976;29:626-33. CrossrefMedlineGoogle Scholar4. FARRELLURENPERKINSJOSHUABARIDKRONENBERG GRKDPH. Androgen-induced hepatoma. Lancet. 1975;1:430-1. CrossrefMedlineGoogle Scholar5. MOKROHISKYAMBRUSOHATHAWAY SDW. Fulminant hepatic neoplasia after androgen therapy. N Engl J Med. 1977;296:1411-2. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: WYLIE L. OVERLY, M.D.; JOSEPH A. DANKOFF, B.S.; BARBARA K. WANG, M.D.; USHA D. SINGH, M.D.Affiliations: Latrobe Area Hospital Latrobe, PA 15650 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byToxin- and Drug-Induced PathologiesMale Hypogonadism and AgingSorption of 17α-Methyltestosterone onto Soils and SedimentToxin- and Drug-Induced PathologiesDoping and Urologic TumorsNutrition, Pharmacology, and Psychology in SportsAnabolic SteroidsFoie et sportAntioxidant Effect of ECG on Testosterone Propionate Induced Chromosome DamageAntigenotoxic Effect of Genistein and Gingerol on Genotoxicity Induced by Norethandrolone and Oxandrolone in Cultured Human LymphocytesTestosterone treatment to mimic hormone physiology in androgen replacement therapyTroubles hépato-digestifs du sportifHormone Abuse in Adolescents and AdultsPathologie hépatogastroentérologique du sportifAndropause: Is Androgen Replacement Therapy Indicated for the Aging Male?Androgens and liver tumors: Fanconi's anemia and non-Fanconi's conditionsHígado y deporteAdverse drug reactions in athletesReferencesReversibility of the effects on blood cells, lipids, liver function and hormones in former anabolic–androgenic steroid abusersAnabolic Steroid-induced Hepatic Adenomas with Spontaneous Haemorrhage in a BodybuilderEstudio de 43 ciclos de tratamiento con anabolizantes esteroideos en deportistas: usos y efectos secundariosIntratesticular leiomyosarcoma in a young man after high dose doping with oral-turinabolO uso de esteróides anabolizantes nos esportesAdverse effects of anabolic-androgenic steroids: a reviewAndrogen Use by Athletes: A Reevaluation of the Health RisksA young man with a solitary hepatic massPerformance-Enhancing DrugsHepatotoxityChromosome investigations in weightlifters and powerlifters after intake of anabolic steroidsAnabolic steroids and growth hormoneAnabolic Steroids: Misuse or Abuse?Anabolic steroid abuse and toxicologyAthletes on Anabolic-Androgenic SteroidsLiver pathology associated with the use of anabolic-androgenic steroidsThe Efficacy of Ergogenic Agents in Athletic Competition Part I: Androgenic-Anabolic SteroidsAndrogen associated hepatocellular carcinoma with an aggressive course.Management of the oral and maxillofacial surgery patient on anabolic steroidsPerformance-enhancing aids in sport: health consequences and nutritional alternatives.Steroid Anabolic Drugs and Arterial Complications in an Athlete—A Case HistoryAnabolic Steroid Use in Adolescent AthletesAnabolic Steroids - a Review of the Clinical Toxicology and Diagnostic ScreeningAdverse Effects of Anabolic SteroidsDrugs in AthleticsHépatite virale atypique chez un sportif utilisant les anabolisantsAnabolic Steroids and Athletic PerformanceCardiomyopathy and Cerebrovascular Accident Associated With Anabolic-Androgenic Steroid UseAnabolic steroid use by athletesSports MedicineDrug Abuse in Body Builders in the West of ScotlandThe behavioral and toxicological effects of testosterone pellet implantationTHE SPECTRUM OF HEPATOTOXICITY DUE TO DRUGSFundamentals of Hormone Treatment of Nonendocrine DisordersThe Use of Drugs in SwimmingSex hormones and related compounds including oral contraceptivesDrug Testing in SportsAnabolic steroids and colonic cancerAnabolic steroids: A review of the literatureAnabolic Steroids 1 January 1984Volume 100, Issue 1Page: 158-159KeywordsAndrogensAnemiaHepatocellular carcinomaSkeletal muscles ePublished: 1 December 2008 Issue Published: 1 January 1984 PDF downloadLoading ...