Gastric Secretion-The Electrolytes before and Their Changes at Various Periods after Histamine Stimulation
Authors: Lay Martin, Morten Morganstern, M. L. Carroll
Journal: Annals of Internal Medicine (1932)

Article1 July 1932Gastric Secretion-The Electrolytes before and Their Changes at Various Periods after Histamine StimulationLAY MARTIN, B.S., M.D., F.A.C.P., MORTEN MORGANSTERN, M.D., M. L. CARROLL, A.B.LAY MARTIN, B.S., M.D., F.A.C.P.Search for more papers by this author, MORTEN MORGANSTERN, M.D.Search for more papers by this author, M. L. CARROLL, A.B.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-6-1-91 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIntroductionThe institution of hypodermic injections of histamine as a gastric stimulant, has enabled investigators to obtain undiluted gastric juice with much more facility than previously; no corrections have to be made for dilution by an alcohol meal.Gamble and McIver1determined the amount of fixed base in a Pavlov pouch from the fundic end of the stomach. They found a fairly constant level of Cl1but a varying amount of base. The level was low on a meal diet, and high on a fasting stomach. The gastric Cl1value (158 c.c. 0.1 N per 100 c.c.) is near the...References1 GAMBLEMCIVER JLMA: Fixed base in gastric juice, Proc. Soc. Exper. Biol. and Med., 1925-26, xxiii, 439. Google Scholar2 MACLEANGRIFFITHS HWJ: The automatic regulation of gastric acidity, Jr. Physiol., 1928, lxvi, 356. CrossrefGoogle Scholar3 MACLEANGRIFFITHSHUGHES HWJTA: The relationship of peptic activity to neutral chloride secretion during gastric digestion in man, Jr. Physiol., 1929, lxvii, 409. CrossrefGoogle Scholar4 BOLDYREFF W: The self-regulation of the acidity of the gastric contents and the real acidity of the gastric juice, Quart. Jr. Exper. Physiol., 1915, viii, 1. Google Scholar5 MACLEANGRIFFITHS HWJ: The factors influencing the concentration of hydrochloric acid during gastric digestion, Jr. Physiol., 1928, lxv, 63. CrossrefGoogle Scholar6 BULGERSTROUDHEIDEMAN HACMML: Studies of the chemical mechanism of hydrochloric acid secretion. I. Electrolyte variations in human gastric juice, Jr. Clin. Invest., 1927-28, v, 547. Google Scholar7 POLLANDROBERTSBLOOMFIELD WSAMAL: The chloride, base and nitrogen content of gastric juice after histamine stimulation, Jr. Clin. Invest., 1927-28, v. 611. Google Scholar8 BLOOMFIELDROBERTSPOLLAND ALAMWS: The composition of the gastric secretion in cases of anacidity, Trans. Assoc. Am. Phys., 1928, xliii, 242. Google Scholar9 CLARK WM: The determination of hydrogen ions, Third Edition, 1928, Williams and Wilkins, Baltimore. Google Scholar10 VAN SLYKE DD: The determination of chlorides in blood and tissues. Jr. Biol. Chem., 1923, lviii, 523. CrossrefGoogle Scholar11 STADIEROSS WCEC: A micromethod for the determination of base in blood and serum and other biological materials, Jr. Biol. Chem., 1925, lxv, 735. CrossrefGoogle Scholar12 BENEDICTTHEIS SRRC: A modification of the molybdic method for the determination of inorganic phosphorus in serum. Jr. Biol. Chem., 1924, lxi, 63. CrossrefGoogle Scholar13 VAN SLYKECULLEN DDGE: Studies of acidosis. I. The concentration of the blood plasma; its significance and its determination as a measure of acidosis, Jr. Biol. Chem., 1927, xxx, 289. Google Scholar14 MARTIN L: Biliary, pancreatic and duodenal studies. II. Estimation of pancreatic enzymes and value of such determinations from a clinical standpoint, Arch. Int. Med., 1927, xxxix, 343-355. CrossrefGoogle Scholar15 MICHAELIS L: Some problems concerning the gastric juice, Harvey Lectures, 1926-27, xxii, 59. Google Scholar16 VAN SLYKEHASTINGSHILLERSENDROY DDABAJ: Studies of gas and electrolyte equilibria in blood. XIV. The amounts of alkali bound by serum albumin and globulin, Jr. Biol. Chem., 1928, lxxix, 769. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Baltimore, Md.*From the Gastro-Intestinal and Chemical Divisions of the Department of Medicine of the Johns Hopkins University.†Delivered in part before the Baltimore Meeting of the American College of Physicians, March 23, 1931. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byUntersuchung der Körperflüssigkeiten und AusscheidungenStudies on the non-parietal component of gastric secretion in humans 1 July 1932Volume 6, Issue 1Page: 91-128KeywordsAlcoholsDietGastroenterology and hepatologyHistamineSaltsStomach ePublished: 1 December 2008 Issue Published: 1 July 1932 PDF downloadLoading ...