Intravenous Gamma-Globulin, Antiphospholipid Antibodies, and Pregnancy
Authors: Ann Parke
Journal: Annals of Internal Medicine (1989)

Letters and Corrections15 March 1989Intravenous Gamma-Globulin, Antiphospholipid Antibodies, and PregnancyAnn Parke, MBBS, Donald Maier, MD, Daniel Wilson, BA, John Andreoli, MD, Mark Ballow, MDAnn Parke, MBBSSearch for more papers by this author, Donald Maier, MDSearch for more papers by this author, Daniel Wilson, BASearch for more papers by this author, John Andreoli, MDSearch for more papers by this author, Mark Ballow, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-110-6-495_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editor: In their letter ( 1 ) on the use of intravenous immunoglobulin therapy (IVIG) in pregnant women with antiphospholipid antibodies and a history of fetal loss, Francois and colleagues suggest that IVIG may be the safest therapy to use in such women. From our experience with a young woman with the primary antiphospholipid antibody syndrome, we agree with their recommendation.In a 29-year-old white woman who previously had five spontaneous abortions, a full gynecologic examination failed to show any cause for her recurrent abortions. Tests for autoantibodies, including antiphospholipid (APL) antibodies, indicated the presence of numerous autoantibodies,...References1. FrancoisFreundDarios AMF. Repeated fetal losses and the lupus anticoagulant. Ann Intern Med. 1988;109:993-4. LinkGoogle Scholar2. ParkeMaierHakimRandolphAndreoli ADCJJ. Subclinical autoimmune disease and recurrent spontaneous abortion. J Rheumatol. 1986;13:1178-80. MedlineGoogle Scholar3. LubbePalmerButler WSW. Fetal survival after prednisone suppression of maternal lupus anticoagulant. Lancet. 1983;1:1361-3. CrossrefMedlineGoogle Scholar4. BranchScottKochenourHershgold DJNE. Obstetric complications associated with the lupus anticoagulant. N Engl J Med. 1985;313:1322-6. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: University of Connecticut School of Medicine Farmington, CT 06032 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByManagement of pregnant women with antiphospholipid antibodiesThe treatment of anti-phospholipid syndrome: A comprehensive clinical approachAdditional Treatments for High-Risk Obstetric Antiphospholipid Syndrome: a Comprehensive ReviewPathogenesis and management of antiphospholipid syndromeIntravenous immunoglobulins and antiphospholipid syndrome: How, when and why? 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