XANTHOMATOUS BILIARY CIRRHOSIS (A CLINICAL SYNDROME)
Authors: H E MacMAHON, S J THANNHAUSER
Journal: Annals of Internal Medicine (1949)

Article1 January 1949XANTHOMATOUS BILIARY CIRRHOSIS (A CLINICAL SYNDROME)H. EDWARD MACMAHON, S. J. THANNHAUSERH. EDWARD MACMAHON, S. J. THANNHAUSERAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-30-1-121 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptEvidence of skin xanthoma with chronic jaundice and liver disease in relatively rare cases has been recognized for a long time and recorded in the literature by various authors: Addison and Gull,11851; Moxon,21873; Pye-Smith,31873; Hutchinson, Sangster and Crocker,41882; Balzer,51884; Hardaway,61890; Futcher,71905; Posner,81909; Chvostek,91911; Dyke,101928; Weidman and Freeman,111924; Buerger,121934; Weidman and Boston,131937. However no attempts were made to match various characteristic symptoms to a definite clinical entity. Thannhauser and Magendantz14in 1937 and Thannhauser15in 1940 described as "xanthomatous biliary cirrhosis" a typical clinical syndrome characterized by the...Bibliography1. ADDISONGULL TW: On a certain affection of the skin, vitiligoidea—(a) plana; (b) tuberosa with remarks, Guy's Hosp. Rep., 1851, vii, 265. Google Scholar2. MOXON : Jaundice and xanthelasma, Trans. Path. Soc. London, 1873, xxiv, 129. Google Scholar3. PYE-SMITH PH: Xanthelasma of skin, peritoneum and mucous membrane associated with jaundice, Trans. Path. Soc. London, 1873, xxiv, 250. Google Scholar4. HUTCHINSONSANGSTERCROCKER JAHR: Report on cases of xanthoma multiplex brought before the pathological society by James Startin and S. Mackenzie, Trans. Path. Soc. London, 1881-1882, xxxiii, 376. Google Scholar5. BALZER F: Sur l'etiolige de xanthoma, Arch. de physiol. norm. et path., 1884, iv, 65. Google Scholar6. HARDAWAY W: Disappearance of extensive eruption of xanthoma, Jr. Cutan. and Genito-Urin. Dis., 1890, viii, 21. 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MACMAHON HE: Biliary xanthomatosis (xanthomatous biliary cirrhosis), Am. Jr. Path., 1948, xxiv, 527. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Boston, Massachusetts*Received for publication October 25, 1947.From the Joseph H. Pratt Diagnostic Hospital and Tufts College Medical School, Boston, Massachusetts. Aided in part by grants from the Rockefeller Foundation and the Godfrey Hyams Trust Fund. 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