Delayed Syndrome of Inappropriate Antidiuretic Hormone Secretion 1 Year after a Head Injury
Authors: P Dileep Kumar, Chorthip Nartsupha, Richard J. Koletsky
Journal: Annals of Internal Medicine (2001)

Letters20 November 2001Delayed Syndrome of Inappropriate Antidiuretic Hormone Secretion 1 Year after a Head InjuryP Dileep Kumar, MD, Chorthip Nartsupha, MD, and Richard J. Koletsky, MDP Dileep Kumar, MDHuron Hospital–Cleveland Clinic Health System; Cleveland, OH 44112 (Kumar, Nartsupha, Koletsky), Chorthip Nartsupha, MDHuron Hospital–Cleveland Clinic Health System; Cleveland, OH 44112 (Kumar, Nartsupha, Koletsky), and Richard J. Koletsky, MDHuron Hospital–Cleveland Clinic Health System; Cleveland, OH 44112 (Kumar, Nartsupha, Koletsky)Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-135-10-200111200-00027 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Intracranial disease, such as trauma, tumors, infections, and neurosurgery, can cause an immediate and short-lived syndrome of inappropriate antidiuretic hormone secretion (SIADH) (1). We report a case of delayed SIADH presenting 1 year after a head injury.A 38-year-old man had bilateral frontal lobe contusions and subarachnoid hemorrhage in May 1998 after an assault. He improved with conservative treatment. He was seen in August 1999 with generalized tonic-clonic seizures. His pulse was 55 beats/min, his blood pressure was 116/73 mm Hg, and the results of the rest of the examination were normal. Sodium level was 119 mmol/L, ...References1. Adams DR, Victor M, Ropper AH. Principles of Neurology. 6th ed. New York: McGraw-Hill; 1997. Google Scholar2. Harrigan MR. Cerebral salt wasting syndrome: a review. Neurosurgery. 1996;38:152-60. [PMID: 8747964] CrossrefMedlineGoogle Scholar3. Isotani E, Suzuki R, Tomita K, Hokari M, Monma S, Marumo F, et al . Alterations in plasma concentrations of natriuretic peptides and antidiuretic hormone after subarachnoid hemorrhage. Stroke. 1994;25:2198-203. [PMID: 7974545] CrossrefMedlineGoogle Scholar4. Verbalis JG. The syndrome of inappropriate antidiuretic hormone secretion and other hypoosmolar disorders.. In: Schrier RW, Gottschalk CW, eds. Diseases of the Kidney. 6th ed. Boston: Little, Brown; 1997. Google Scholar Author, Article, and Disclosure InformationAuthors: P Dileep Kumar, MD; Chorthip Nartsupha, MD; Richard J. Koletsky, MDAffiliations: Huron Hospital–Cleveland Clinic Health System; Cleveland, OH 44112 (Kumar, Nartsupha, Koletsky)Note: An abstract of this paper was presented at the annual meeting of the Midwestern Section, American Federation of Medical Research, 21–23 September 2000, Chicago, Illinois. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byHigh Urinary Sodium Concentrations in Severe SIADH: Case Reports of 2 Patients and Literature ReviewPersistent syndrome of inappropriate antidiuretic hormone secretion following traumatic brain injurySerial plasma vasopressin concentration in healthy and hospitalised neonatal foalsRecurrent Hyponatremia After Traumatic Brain Injury 20 November 2001Volume 135, Issue 10Page: 932-933KeywordsEpileptic seizuresFrontal lobeHead injuryHyponatremiaSaltsSodiumSyndrome of inappropriate antidiuretic hormone secretionUric acidUrineVasopressin ePublished: 20 November 2001 Issue Published: 20 November 2001 Copyright & PermissionsCopyright © 2001 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...