THE INCIDENCE AND ETIOLOGIC BACKGROUND OF CHRONIC BIOLOGIC FALSE-POSITIVE REACTIONS IN SEROLOGIC TESTS FOR SYPHILIS: PRELIMINARY REPORT
Authors: J E MOORE, C F MOHR
Journal: Annals of Internal Medicine (1952)

Article1 December 1952THE INCIDENCE AND ETIOLOGIC BACKGROUND OF CHRONIC BIOLOGIC FALSE-POSITIVE REACTIONS IN SEROLOGIC TESTS FOR SYPHILIS: PRELIMINARY REPORTJOSEPH EARLE MOORE, M.D., CHARLES F. MOHR, M.D., F.A.C.P.JOSEPH EARLE MOORE, M.D.Search for more papers by this author, CHARLES F. MOHR, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-37-6-1156 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptPresent standard serologic tests for syphilis (hereafter abbreviated STS), routinely discovered in patients who have no history or physical evidence of that infection, may represent either latent syphilis, acquired or congenital, or biologic false-positive reactions (hereafter abbreviated BFP).BFP reactors may be divided into two categories, acute and chronic.1 The acute reactions are due to a large number of infections, bacterial, viral, plasmodial, rickettsial or protozoal. They appear during or immediately after such a precipitating infectious cause, and regress spontaneously to normality within a brief period, not exceeding six months.Chronic BFP reactors, on the other hand, are characterized by...Bibliography1. MooreMohr JECF: The classification, recognition, incidence, and etiologic background of biologic false positive serologic tests. Preliminary report, J. A. M. A. 150: 467, 1952. CrossrefMedlineGoogle Scholar2. NelsonMayer RAMM: Immobilization of T. pallidum in vitro by antibody produced in syphilitic infection, J. Exper. Med. 89: 369, 1949. CrossrefMedlineGoogle Scholar3. NelsonZheutlinAustinHill RAHEPGJH: Application of treponemal immobilization test to problems of clinical syphilis. Presented at the Symposium on the Later Advances in the Study of the Venereal Diseases, Washington, D. C., April 28, 1950. Google Scholar4. Nelson RA: Treponemal immobilization test program in the United States Navy. Presented at the Symposium on Recent Advances in the Study of Venereal Diseases, Washington, D. C., May 2, 1952. Google Scholar5. MacLaganMartinLunnon NFNHJB: The mechanism and interrelationships of the flocculation tests, J. Clin. Path. 5: 1, 1952. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Baltimore, Maryland*Received for publication May 17, 1952.From the Venereal Disease Division of the Medical Clinic, Johns Hopkins University and Hospital.This study has been supported by a grant-in-aid from the Research Grants and Fellowships Division, National Institutes of Health, United States Public Health Service. 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ROBINSON, M.D., F.A.C.P., JOSEPH J. BUNIM, M.D., F.A.C.P., WILLIAM S. CLARK, M.D., DARRELL C. CRAIN, M.D., F.A.C.P., EPHRAIM P. ENGLEMAN, M.D., F.A.C.P., DONALD C. GRAHAM, M.D., F.R.C.P. (C), MAX M. MONTGOMERY, M.D., F.A.C.P., BERNARD M. NORCROSS, M.D., F.A.C.P., CHARLES RAGAN, M.D., F.A.C.P., MARIAN W. ROPES, M.D., F.A.C.P., EDWARD F. ROSENBERG, M.D., F.A.C.P., CHARLEY J. SMYTH, M.D., F.A.C.P.The treponema pallidum immobilization test in the cerebrospinal fluidThe natural history of systemic lupus erythematosus: An approach to its study through chronic biologic false positive reactorsNeedle biopsy of the kidney in the diagnosis of disseminated lupus erythematosusAPICAL LOCALISATION OF PULMONARY TUBERCULOSISCONVULSION DEPENDENCESERUM TESTS FOR SYPHILISSerum Tests for SyphilisStudies on the Treponemal Immobilization TestTHE CHANGING PATTERN OF SYPHILIS 1941-1953 1 December 1952Volume 37, Issue 6Page: 1156-1161KeywordsBiologicsCongenital syphilisFellowshipsHospitalsMedical servicesPrevention, policy, and public healthResearch grantsRocky Mountain spotted feverSexually transmitted diseasesSyphilis ePublished: 1 December 2008 Issue Published: 1 December 1952 PDF downloadLoading ...