BENIGN AND MALIGNANT GASTRIC ULCERS: THEIR RELATION AND CLINICAL DIFFERENTIATION
Authors: Walter Lincoln Palmer
Journal: Annals of Internal Medicine (1939)

Article1 August 1939BENIGN AND MALIGNANT GASTRIC ULCERS: THEIR RELATION AND CLINICAL DIFFERENTIATIONWALTER LINCOLN PALMER, M.D.WALTER LINCOLN PALMER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-13-2-317 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe purpose of this paper is to consider briefly the relationship between benign and malignant gastric ulcers, the clinical differentiation of the two lesions, and the therapeutic implications.RELATIONSHIPA few years after Cruveilhier differentiated gastric ulcer from gastric carcinoma, Rokitansky described a case interpreted as showing the carcinomatous transformation of a benign ulcer. An enormous controversial literature has since developed regarding, first, the existence of carcinomatous degeneration in ulcer, and, secondly, the incidence of such a process. A critical review of the subject has led me to doubt the existence of such a transformation. The alleged evidence for such...References1. KLEIN SH: Origin of carcinoma in chronic gastric ulcer, Arch. Surg., 1938, xxxvii, 155. CrossrefGoogle Scholar2. SCOTTMIDER WJGB: Malignancy in the chronic gastric ulcer, Am. Jr. Surg., 1938, xl, 47. Google Scholar3. BLOOMFIELD AL: The diagnosis of early cancerous changes in peptic ulcer, Jr. Am. Med. Assoc., 1935, cix, 1197. CrossrefGoogle Scholar4. SCHMIDT A, cited in MOSKOWICZ, L.: Über einen Fall von jungem "Ulcuscarcinom" des Magens, Virchow's Arch. f. path. Anat., 1924, ccliii, 511. NIELSEN, N. A.: About the choice between medical and surgical treatment of ulcus ventriculi s. duodeni, Acta chir. Scand., 1922-23, lv, 57. HAUSER, G.: Zur Frage von der krebsigen Entartung des chronischen Magengeschwürs, München, med. Wchnschr., 1910, lvii, 1209. STROMEYER, F.: Die Pathogenese des Ulcus ventriculi, zugleich ein Beitrag zur Frage nach den Beziehungen zwischen Ulcus und Carcinom, Beitr. z. path. Anat. u. z. allg. Path., 1912, liv, 1. ASCHOFF, L.: Über die mechanischen Momente in der Pathogenese des runden Magengeschwürs und über seine Beziehungen zum Krebs, Deutsch. med. Wchnschr., xxxviii, 494. EWING, J.: Relation of gastric ulcer to cancer, Ann. Surg., 1918, lxvii, 715. WILENSKY, A. O., and THALHEIMER, W.: Etiological relationship of benign ulcer to carcinoma of the stomach, Ann. Surg., 1918, lxvii, 215. KONJETZNY, G. E.: Der jetzige Stand der Lehre von der Beziehung des Magenkarzinoms zum Magengeschwür, Deutsch. med. Wchnschr., 1920, xlvi, 286. EWING, J.: Beginnings of gastric cancer, Am. Jr. Surg., 1936, xxxi, 204. Google Scholar5. JARCHO S: Diffusely infiltrative carcinoma, Arch. Path., 1936, xxii, 674. Google Scholar6. PALMERRENSHAW WLJF: Carcinoma ex ulcere—a consideration of the problem with especial reference to the rôle of acid gastric secretion (to be published). Google Scholar7. BLOOMFIELD .3 Google Scholar8. RIVERSDRY ABTJ: Differentiation of benign and malignant gastric ulcers, Arch. Surg., 1935, xxx, 702. CrossrefGoogle Scholar9. MATTHEWS WB: Peptic ulcer involving the greater curvature of the stomach, Ann. Surg., 1935, ci, 844. CrossrefGoogle Scholar10. KONJETZNY GE: Der Magenkrebs, Stuttgart, Ferdinand Enke, 1938, p. 158. Google Scholar11. GRAHAM RR in discussion on SCOTT, W. J. M.: The possibility of malignancy as it affects the treatment of chronic gastric ulcer, Ann. Surg., 1935, cii, 586. Google Scholar12. HOLMESHAMPTON GWAO: The incidence of carcinoma in certain chronic ulcerating lesions of the stomach, Jr. Am. Med. Assoc., 1932, xcix, 905. CrossrefGoogle Scholar13. PALMERSCHINDLERTEMPLETON WLRFE: The development and healing of gastric ulcer, a clinical, gastroscopic and roentgenologic study, Am. Jr. Digest. Dis., 1938, v, 501. CrossrefGoogle Scholar14. CARMAN RD: New roentgen-ray sign of ulcerating gastric cancer, Jr. Am. Med. Assoc., 1921, lxxvii, 990. Google Scholar15. SCHINDLER R: Gastroscopy, the endoscopic study of gastric pathology, 1937, The University of Chicago Press, Chicago, p. 256, figure 84. PALMER, W. L., and FERRY, J. L.: Paper to be published. MASS, M., and STEIGMANN, F.: Carcinoma in clinically benign gastric ulcer, Illinois Med. Jr., 1939, lxxv, 120. Google Scholar16. SCHINDLER ,15 p. 265. Google Scholar17. BLOOMFIELD .3 Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Chicago, Illinois*Read at the New Orleans meeting of the American College of Physicians, March 30, 1939.From the Department of Medicine, the University of Chicago. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byGastrointestinal tractGastric UlcerationsTHE BLOOD GROUPS OF GASTRIC ULCER-CANCERRelationship of Peptic Ulceration to Superficial Spreading Carcinoma of the StomachDiagnostic Accuracy in Gastric UlcerBENIGN ULCER AND CARCINOMA OF THE STOMACHCarcinoma of the Stomach: Diagnostic and Therapeutic ConsiderationsBenign ulcer of the greater curvature of the stomachMalignant Degeneration of Chronic Benign Gastric UlcerDiagnosis of Gastroduodenal DiseaseThe Medical Treatment of Peptic UlcerConsiderations on the diagnosis of large gastric ulcers and implications as to treatmentCANCER AND PRECANCER OF THE STOMACH 1 August 1939Volume 13, Issue 2Page: 317-338KeywordsGastric ulcersLesionsUlcers ePublished: 1 December 2008 Issue Published: 1 August 1939 PDF downloadLoading ...