ABSORPTION AND EXCRETION OF IRON
Authors: Alexander G. Little, Marschelle H. Power, E. G. Wakefield
Journal: Annals of Internal Medicine (1945)

Article1 October 1945ABSORPTION AND EXCRETION OF IRONALEXANDER G. LITTLE JR., M.D., MARSCHELLE H. POWER, PH.D., E. G. WAKEFIELD, M.D.ALEXANDER G. LITTLE JR., M.D.Search for more papers by this author, MARSCHELLE H. POWER, PH.D.Search for more papers by this author, E. G. WAKEFIELD, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-23-4-627 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptConsidering the importance of iron in the body and the extensive work that has been done on this subject, still relatively little is known concerning metabolism of iron. During most of the last century many extensive arguments were carried on as to whether or not iron was absorbed at all. The misconception that it was not absorbed arose from the fact that the small amounts of iron in the body could not be detected by chemical methods available at the time. As late as 1893, Stockman1felt it necessary to refute the theory, which was apparently current then, that the...Bibliography1. STOCKMAN R: The treatment of chlorosis by iron and some other drugs, Brit. Med. Jr., 1893, i, 881-885; 942-944. CrossrefGoogle Scholar2. STARLING EH: Human physiology, Ed. 6, 1933, Lea and Febiger, Philadelphia, 1122 pp. Google Scholar3. SZENT-GYÖRGYI A: Eine Farbenreaktion der Ascorbinsäure, Ztschr. f. physiol. Chem., 1934, ccxxv, 168. CrossrefGoogle Scholar4. HEILMEYER L: Die Behandlung eisenempfindlicher Anämien mit askorbinsaurem Eisen, zugleich ein Beitrag zum Mechanismus der Eisenwirkung und zur Frage der Eisenmangelkrankheit, Deutsch. Arch. f. klin. Med., 1936, clxxix, 216-231. Google Scholar5. FLEISCHHACKERSCHÜRER-WALDHEIM HF: Zur peroralen und intravenösen Therapie mit ascorbinsaurem Eisen, Wien. klin. Wchnschr., 1938, li, 776-780. Google Scholar6. FRIEND DG: Iron ascorbate in the treatment of anemia, New England Jr. Med., 1938, ccxix, 910-912. CrossrefGoogle Scholar7. MAURERSCHIEDT KB: Das Verhalten der d-Arabascorbinsäure und des Vitamins C gegenüber Ferrosalzen, Biochem. Ztschr., 1936, cclxxxv, 67. Google Scholar8. MOORE CV: Studies in iron transportation and metabolism; chemical methods and normal values for plasma iron and "easily split-off" blood iron, Jr. Clin. Invest., 1937, xvi, 613-626. CrossrefGoogle Scholar9. HENRIQUESROLAND VH: Zur Frage des Eisenstoffwechsels, Biochem. Ztschr., 1928, cci, 479-485. Google Scholar10. HAHNWHIPPLE PFGH: Radioactive iron and its metabolism in anemia, Jr. Am. Med. Assoc., 1938, cxi, 2285-2286. CrossrefGoogle Scholar11. HAHNBALELAWRENCEWHIPPLE PFWFEOGH: Radioactive iron and its metabolism in anemia, Jr. Exper. Med., 1939, lxix, 739-753. CrossrefGoogle Scholar12. HAHNBALEHETTIGKAMENWHIPPLE PFWFRAMDGH: Radioactive iron and its excretion in urine, bile and feces, Jr. Exper. Med., 1939, lxx, 443-451. CrossrefGoogle Scholar13. QUINKE : Quoted by GOTTLIEB, R.: Ueber die Ausscheidungsverhältnisse des Eisens, Ztschr. f. physiol. Chem., 1891, xv, 371-386. Google Scholar14. MCCANCEWIDDOWSON RAEM: Fate of elements removed from blood-stream during treatment of polycythaemia by acetyl-phenylhydrazine, Quart. Jr. Med., 1937, vi, 277-286. Google Scholar15. MCCANCEWIDDOWSON RAEM: Absorption and excretion of iron, Lancet, 1937, ii, 680-684. CrossrefGoogle Scholar16. FARRARGOLDHAMER GESM: The iron requirement of the normal human adult, Jr. Nutr., 1935, x, 241-254. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication December 29, 1944.Abridgment of thesis submitted by Dr. Little to the Faculty of the Graduate School of the University of Minnesota in partial fulfillment of the requirements for the degree of M.S. in Surgery.From the Mayo Foundation (Fellow in Surgery, Dr. Little) (Division of Biochemistry, Dr. Power) and Mayo Clinic (Division of Medicine, Dr. Wakefield). Since this paper was written Dr. Little has entered the army and is now an officer of the Medical Corps, Army of the United States. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byIron Metabolism and Iron Deficiency AnemiaDie Grundstoffe der NahrungDas Harneisen in der normalen Sp�tschwangerschaft und bei Sp�ttoxikosenThe availability of iron in certain grass, clover and herb species. I. Perennial ryegrass, cocksfoot and timothyFunktion und Stoffwechsel der Schwermetalle�ber das Urineisen In der Gravidit�tstoxikosePhysiologische Chemie einzelner Lebensvorgänge und Organe (Fortsetzung)IRON EXCRETION IN THE MOUSE 1 October 1945Volume 23, Issue 4Page: 627-633KeywordsBiochemistryExcretionGraduate medical educationSurgery ePublished: 1 December 2008 Issue Published: 1 October 1945 PDF downloadLoading ...