IDIOPATHIC AND SECONDARY THROMBOCYTOPENIC PURPURA: CLINICAL STUDY AND EVALUATION OF 381 CASES OVER A PERIOD OF 28 YEARS
Authors: Charles A. Doan, Bertha A. Bouroncle, Bruce K. Wiseman
Journal: Annals of Internal Medicine (1960)

Article1 November 1960IDIOPATHIC AND SECONDARY THROMBOCYTOPENIC PURPURA: CLINICAL STUDY AND EVALUATION OF 381 CASES OVER A PERIOD OF 28 YEARSCHARLES A. DOAN, M.D., F.A.C.P., BERTHA A. BOURONCLE, M.D., BRUCE K. WISEMAN, M.D., F.A.C.P.CHARLES A. DOAN, M.D., F.A.C.P., BERTHA A. BOURONCLE, M.D., BRUCE K. WISEMAN, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-53-5-861 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptFor the last 28 years we have been concerned with the study of thrombocytopenic purpura. Our spiraling interest has paralleled the progressive increase in the total number of patients with this syndrome seen in our Hematology Clinics in each five-year period (figure 1).Until 1950 the only major effective therapeutic procedure available was splenectomy. Since then, corticosteroids have been selectively employed and recommended.The purpose of this study is to present an evaluation of the clinical and hematologic findings in thrombocytopenic purpura; to establish a comparison of the results obtained with splenectomy versus corticosteroid therapy; to report the postsplenectomy life...Bibliography1. KrumbhaarLippincott EBSW: The post mortem weight of the "normal" human spleen at different ages, Am. J. M. Sc. 197: 344, 1939. CrossrefGoogle Scholar2. CarpenterWintrobeFullerHautCartwright AFMMEAAGE: Treatment of idiopathic thrombocytopenic purpura, J. A. M. A. 171: 103/1911, 1959. Google Scholar3. Harrington WJ: Idiopathic thrombocytopenic purpura in the adult, presented before The Blood Club meeting, Chicago, November, 1959. Google Scholar4. DameshekRubioMahoneyReevesBurgin WFYPWHLA: Treatment of idiopathic thrombocytopenic purpura (ITP) with prednisone, J. A. M. A. 166: 1805, 1958. CrossrefMedlineGoogle Scholar5. 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KalinowskiWalker SZJ: Thrombocytopenic purpura in tuberculosis, Brit. J. Tuberc. 50: 239, 1956. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Columbus, Ohio*Received for publication June 6, 1960.Presented at the Forty-first Annual Session of The American College of Physicians, San Francisco, California, April 7, 1960.From the Hematology Division of the Medical Department, Ohio State University, Columbus.†Deceased.Requests for reprints should be addressed to Charles A. Doan, M.D., Dean, Director of the Health Center, The Ohio State University College of Medicine, 1645 Neil Avenue, Columbus 10, Ohio. 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