EFFECTS OF ADRENOCORTICOTROPIC HORMONE IN PNEUMONIA: CLINICAL, BACTERIOLOGICAL AND SEROLOGICAL STUDIES
Authors: E H KASS, S H INGBAR, M FINLAND
Journal: Annals of Internal Medicine (1950)

Article1 November 1950EFFECTS OF ADRENOCORTICOTROPIC HORMONE IN PNEUMONIA: CLINICAL, BACTERIOLOGICAL AND SEROLOGICAL STUDIESEDWARD H. KASS, PH.D., M.D., SIDNEY H. INGBAR, M.D., MAXWELL FINLAND, M.D., F.A.C.P.EDWARD H. KASS, PH.D., M.D.Search for more papers by this author, SIDNEY H. INGBAR, M.D.Search for more papers by this author, MAXWELL FINLAND, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-33-5-1081 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlthough adrenal cortical and pituitary adrenocorticotropic hormones have produced remarkable alterations in the course of many clinical disorders,5, 9the mechanisms by which these changes are induced remain obscure. Immunologic factors have been considered to play an important rôle in the pathogenesis of, or recovery from, many of the diseases in which cortisone and ACTH have exerted apparently beneficial effects. Because adrenal hormones have been implicated in immunologic processes,9, 10attempts have been made to explain the effects of cortisone and ACTH in terms of immunologic mechanisms. However, it is obviously difficult to study the effects of ACTH on immunologic...Bibliography1. CecilBaldwinLarsen RLHSNP: Lobar pneumonia. A clinical and bacteriologic study of 2000 typed cases, Arch. Int. Med. 40: 253-280, 1927. CrossrefGoogle Scholar2. FinlandDowling MHF: Pneumococcus type II and type V infections, Arch. Int. Med. 58: 598-619, 1936. CrossrefGoogle Scholar3. FinlandKassIngbar MEHSH: Effects of ACTH in primary atypical (viral) pneumonia and in pneumococcal pneumonia (Preliminary report). In Proc. 1st Clinical ACTH Conference, Ed. J. R. Mote, Philadelphia, Blakiston Co., 1950, pp. 529-535. 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White A: Relation of adrenals to immunity, Bull. New York Acad. Med. 24: 26-31, 1948. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Boston, Massachusetts*Received for publication July 7, 1950.From the Thorndike Memorial Laboratory, Second and Fourth Medical Services (Harvard), Boston City Hospital and the Department of Medicine, Harvard Medical School, Boston, Mass.Aided by a grant from the United States Public Health Service.†Senior Fellow in Virus Diseases, National Research Council.‡Furnished by Dr. John R. Mote, of the Armour Laboratories. Nextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byHistorical OverviewEndocrine Changes in Critical IllnessA Review of the Adrenal Cortex and Severe Inflammation: Quest of the ???Eucorticoid??? StateAdjunctive Therapies in Severe Community-Acquired PneumoniaEffect of High-Dose Glucocorticoid Therapy on Mortality in Patients with Clinical Signs of Systemic SepsisCorticosteroids in Patients with Septic ShockHigh-Dose Corticosteroids for Septic ShockAntipyretic Potency of Centrally Administered α-Melanocyte Stimulating HormoneBrain and pituitary peptides in thermoregulationGram-negative bacteremiaINFLUENCE OF THE THYMUS-CORTICOTROPIN-GROWTH HORMONE INTERACTION ON THE REJECTION OF SKIN ALLOGRAFTS IN THE RATCorticosteroids and Infectious DiseasesAnti-Immunologic and Anti-Inflammatory Effects of Steroid TherapyProphylaxis in patients receiving adrenal steroid therapySTUDIES ON EXPFRIMENTAL STAPHYLOCOCCAL PNEUMONIAThe mechanism of cortisone's effect of hyperthermia in rabbits induced by 2,4-dinitrophenolErkrankungen des EndokardExperimentelle Untersuchungen �ber Adh�sionseinschr�nkungen im Bauchraum der Ratte durch intraperitoneale HydrocortisongabenThe Specific Diagnosis and Treatment of the PneumoniasACTH and adrenal steroids in the treatment of pneumococcal meningitis in adultsACTH and Adrenocorticosteroids as Therapeutic Adjuncts in Infectious DiseasesHazards and Safeguards in Steroid TherapyDEATHS ASSOCIATED WITH STEROID-HORMONE THERAPYChildren's Medical Center Boston, Mass, USAObservations on the use of ACTH in certain obstetric and gynecologic conditionsAntibiotic therapyBegriffsbestimmungLungenaffektionen und endokrine DrüsenAsthma bronchialeDie EntzündungADRENOCORTICOTROPIC HORMONE AND ADRENAL STEROIDS IN THE MANAGEMENT OF INFECTIOUS DISEASES*WESLEY W. SPINK, M.D., F.A.C.P.Aetiology and pathogenesis of rheumatoid arthritisPhysiology of the Adrenal CortexActh and Cortisone in the Treatment of Atopic DermatitisCORTISONE AND THE TREATMENT OF HEAT STROKE*WILLIAM H. WAUGH, M.D.Use of Cortisone during Penicillin Treatment of Secondary Mucocutaneous Syphilis in a Hypersensitive PatientCortisone and combined antibiotic therapy of acute brucellosis melitensisThe combination of ACTH-cortisone-hydrocortisone with antibiotics in the management of overwhelmingly severe infectionsACTH und Cortison in der ChirurgieDuration of Antipyretic Effect of a Single Injection of Various ACTH PreparationsKombinierte Cortison-Penicillin-Behandlung der experimentellen StreptokokkeninfektionINTERRUPTION BY TOPICAL CORTISONE OF LEUKOCYTIC CYCLES IN ACUTE INFLAMMATION IN MANTHE EFFECT OF ADRENAL CORTICAL HORMONES ON EXPERIMENTAL INFECTIONOBSERVATIONS ON THE EFFECT OF CORTICOSTEROIDS AND GROWTH HORMONE ON RESISTANCE TO EXPERIMENTAL PNEUMOCOCCAL AND INFLUENZA VIRUS INFECTIONSADRENAL HORMONE THERAPY IN VIRAL HEPATITIS. I. THE EFFECT OF ACTH IN THE ACUTE DISEASE*ALFRED S. EVANS, HELMUTH SPRINZ, ROBERT S. NELSONThe prolonged treatment of rheumatoid arthritis with cortisone and corticotropinAdrenocorticotropic hormone in the control of acuteinfantile bronchiolitisEarly effects of Acth on Arterial and Venous blood Glucose and on renal Glucose excretionCirculating blood eosinophils in acute infectious disease and the eosinopenic responseCortisone as an Adjunct to Chloramphenicol in the Treatment of Rocky Mountain Spotted FeverCortisone in Urological Conditions with a Report of a Trial in Interstitial CystitisACTH and Cortisone Treatment of Acute Rheumatic FeverPresent Status of ACTH and Cortisone in TherapyCase 37331ACTH and Cortisone in InfectionLymphoid Tissue of the PharynxCortisone and ACTHThe Role of Adrenal Steroids in Infection and ImmunityExperience With Cortisone in the Treatment of Rheumatoid ArthritisEffects of Cortisone and ACTH 1 November 1950Volume 33, Issue 5Page: 1081-1098KeywordsAdrenocorticotropic hormoneHormonesHospital medicineMedical servicesPathogenesisPneumoniaResearch laboratories ePublished: 1 December 2008 Issue Published: 1 November 1950 Copyright & PermissionsCopyright, 1950, by The American College of PhysiciansPDF downloadLoading ...