ANTIMICROBIAL THERAPY OF PULMONARY TUBERCULOSIS: REVIEW OF SIX YEARS' EXPERIENCE AT FITZSIMONS ARMY HOSPITAL
Authors: Carl W. Tempel, Forrest W. Pitts, William E. Dye
Journal: Annals of Internal Medicine (1953)

Article1 July 1953ANTIMICROBIAL THERAPY OF PULMONARY TUBERCULOSIS: REVIEW OF SIX YEARS' EXPERIENCE AT FITZSIMONS ARMY HOSPITALCARL W. TEMPEL, FORREST W. PITTS, WILLIAM E. DYECARL W. TEMPELSearch for more papers by this author, FORREST W. PITTSSearch for more papers by this author, WILLIAM E. DYESearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-39-1-61 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSix antimicrobial agents have been subjected to a methodical pattern of clinical investigation since 1946 at Fitzsimons Army Hospital. Approximately 1,300 patients have been evaluated under controlled conditions employing streptomycin, para-aminosalicylic acid, amithiozone, viomycin, terramycin and Isoniazid, either singly or in various combinations.1 Therapeutic efficacy, bacteriologic cultural and resistance studies, and toxicity formed the principal criteria for evaluating these drug regimens. Summary data on 875 patients observed on the research wards constitute the basis of this report.Studies were performed on a homogeneous group of patients relative to extent and clinical pathologic type of disease. Almost all were young adult...Bibliography1. Tempel CW: Present status of specific drug treatment of tuberculosis, J. A. M. A. 150: 1165-1170 (Nov. 22) 1952. CrossrefMedlineGoogle Scholar2. 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J. 4: 1 (Jan.) 1953. MedlineGoogle Scholar13. PittsTempelMillerSandsFitzpatrickWeiser FWCWFLJHMJO: Isoniazid-streptomycin in the treatment of pulmonary tuberculosis: a preliminary report, J. A. M. A., in press. Google Scholar14. Pinner M: Pulmonary tuberculosis in the adult, 1945, Charles C. Thomas, Springfield, Illinois, p. 299. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Read before the 119th Meeting of the American Association for the Advancement of Science, December 26, 1952, St. Louis, Missouri. Received for publication March 3, 1953.From the Medical Service and Research and Development Branch, Fitzsimons Army Hospital, Denver, Colorado. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byTrends in the Management of Pulmonary TuberculosisLONG-TERM OXYTETRACYCLINE (TERRAMYCIN) THERAPY IN ADVANCED CHRONIC RESPIRATORY INFECTIONSCurrent Concepts in the Treatment of Pulmonary TuberculosisATYPICAL TUBERCULOSIS OF THE LIVER WITH JAUNDICE*EDWARD A. CLEVE, JOHN R. GIBSON, WILLIAM M. WEBB 1 July 1953Volume 39, Issue 1Page: 61-73KeywordsAdverse reactionsAntimicrobialsHealth services researchIsoniazidMedical servicesStreptomycinToxicityYoung adults ePublished: 1 December 2008 Issue Published: 1 July 1953 PDF downloadLoading ...