CONCERNING THE INFECTIVITY OF SALIVA IN HUMAN RABIES
Authors: S. Edward Sulkin, Carl G. Harford
Journal: Annals of Internal Medicine (1943)

Article1 August 1943CONCERNING THE INFECTIVITY OF SALIVA IN HUMAN RABIESS. EDWARD SULKIN, PH.D., CARL G. HARFORD, M.D.S. EDWARD SULKIN, PH.D.Search for more papers by this author, CARL G. HARFORD, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-19-2-256 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe infectiousness of saliva in rabid animals was demonstrated experimentally by Zinke, Gruner, Salm, Berendt and others in the early part of the last century. Despite the fact, however, that excessive salivation is a common feature of paralytic rabies in man, only few reports are available in the literature concerning the experimental demonstration of virus in the saliva in human rabies. Pasteur, Chamberland and Roux1and Raynaud and Lannelongue2were perhaps the first investigators to demonstrate virus in the saliva of infected human beings. More recently Palawandow and Serebrennaja3demonstrated the presence of the virus in the saliva of one...Bibliography1. PASTEURCHAMBERLANDRoux LPE: Sur une maladie nouvelle provoquée par la salive d'un enfant mort de la rage, Compt.-rend. Acad. d. sc., Paris, 1881, xcii, 159-165. Google Scholar2. RAYNAUDLANNELONGUE MP: Recherches experimentales sur la transmission du virus rabique des l'homme au lapin, Bull. de l'Acad. de méd., Paris, 1881, x, 61-54. Google Scholar3. PALAWANDOWSEREBRENNAJA HAI: Ueber die Anwesenheit des Tollwutvirus in menschlichen Speichel, Ztschr. f. Immunitätsforsch. u. exper. Therap., Ref., 1930, lxvi, 519-529. PALAWANDOW, H., and SEREBRENNAJA, A. I.: Zur Frage der Virulenz des Speichels von an Tollwut erkrankten Menschen, Ztschr. f. Immunitätsforsch. u. exper. Therap., Ref., 1930, lxviii, 236-242. Google Scholar4. PALAWANDOWSEREBRENNAJA HAI: Ueber das Wutvirus in menschlichem Speichel, Ztschr. f. Immunitätsforsch. u. exper. Therap., Ref., 1931, lxxi, 350-351. PALAWANDOW, H., and SEREBRENNAJA, A. I.: Uber einige Eigentümlichkeiten der im Odessaer bakteriologischen Institute isolierten Strassenvira, Ztschr. f. Immunitätsforsch. u. exper. Therap., Ref., 1933, lxxi, 230-238. Google Scholar5. PAWAN JL: Infectivity of saliva in paralytic rabies, Ann. Trop. Med. and Parasitol., 1937, xxxi, 267-270. CrossrefGoogle Scholar6. SABINRUCHMAN ABI: Spread of virus in an unvaccinated case of human rabies, Proc. Soc. Exper. Biol. and Med., 1940, xliv, 572-577. CrossrefGoogle Scholar7. PASTEURCHAMBERLANDRoux LPE: Physiologie experimentale. Nouvelle Communications sur la rage, Compt-rend. Acad. d. sc., Paris, 1884, xcviii, 457-463. Google Scholar8. BARDACH J: Nouvelles recherches sur la rage, Ann. Inst. Pasteur, 1888, ii, 9-17. Google Scholar9. PACE D: Sur l'existence du virus rabique dans le siège de la morsue d'un enfant mort de rage, Ann. Inst. Pasteur, 1903, xvii, 293-297. Google Scholar10. LEACHJOHNSON CNHN: Human rabies with special reference to virus distribution and pathology, Abstracts of Communications, Third Internat. Congress for Microbiology, 1939, 325-326. Google Scholar11. LEACHJOHNSON CNHN: Human rabies, with special reference to virus distribution and titer, Am. Jr. Trop. Med., 1940, xx, 335-340. CrossrefGoogle Scholar12. KRAUSGERLACHSCHWEINBURG RFS: Lyssa bei Mensch und Tier, Vienna, 1936, lxxx, 128-131. Google Scholar13. KOCH J: Handbuch der pathogenen Micro-Organismen, 1930, viii, 553. Google Scholar14. AMOSSTAYLOR HLE: Neutralization of the virus of poliomyelitis by nasal washings, Jr. Exper. Med., 1917, xxv, 507-523. CrossrefGoogle Scholar15. KRAMERSOBELGROSSMANKOSKWITH SDAELHB: Survival of virus of poliomyelitis in oral and nasal secretion of convalescents, Jr. Exper. Med., 1936, lxiv, 173-180. CrossrefGoogle Scholar16. SULKINNAGLE SEN: Demonstration of rabies virus in grossly decomposed animal brains, Jr. Lab. and Clin. Med., 1939, xxv, 94-98. Google Scholar17. RAKESHAFFER GMF: Studies on measles. I. The use of the chorio-allantois of the developing chicken embryo, Jr. Immunol., 1940, xxxviii, 177-200. Google Scholar18. SARRACINOSOULE JBMH: Isolation of virus from feces of mice receiving intranasal inoculations of epidemic influenza virus, Proc. Soc. Exper. Biol. and Med., 1941, xlviii, 188-191. CrossrefGoogle Scholar19. MAINLAND D: The treatment of clinical and laboratory data. An introduction to statistical ideas and methods for medical and dental workers, 1938, Oliver and Boyd, Edinburgh and London. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: St. Louis, Missouri*Received for publication April 18, 1942.From the Virus Laboratory of the St. Louis Health Division and the Department of Bacteriology, Washington University School of Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byOral MicrobiologyRabies 1 August 1943Volume 19, Issue 2Page: 256-262KeywordsBacteriologyRabiesResearch laboratoriesSalivaSalivation ePublished: 1 December 2008 Issue Published: 1 August 1943 PDF downloadLoading ...