URTICARIA OF THE GASTRIC MUCOSA WITH MASSIVE HEMORRHAGE FOLLOWING ORAL PENICILLIN ANAPHYLAXIS
Authors: S P BRALOW, L S GIRSH
Journal: Annals of Internal Medicine (1959)

Case Reports1 August 1959URTICARIA OF THE GASTRIC MUCOSA WITH MASSIVE HEMORRHAGE FOLLOWING ORAL PENICILLIN ANAPHYLAXISS. P. BRALOW, M.D., F.A.C.P., L. S. GIRSH, M.D.S. P. BRALOW, M.D., F.A.C.P.Search for more papers by this author, L. S. GIRSH, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-51-2-384 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIt is not unusual for anaphylaxis to be accompanied by nausea, vomiting and abdominal pain. These attacks may be so severe as to simulate an acute abdominal crisis, and unwarranted surgery may be performed. This syndrome has also been called acute abdominal angioneurotic edema, because the reaction is thought to be due to acute edema of the gastrointestinal mucosa resembling a large hive. Such areas have been described in the bowel wall of patients who were mistakenly subjected to surgery. Gastrointestinal bleeding may sometimes accompany these acute abdominal crises. As a rule, the hemorrhage is accompanied by either urticaria or...Bibliography1. Tuft L: Clinical allergy, 2nd Ed., 1949, Lea and Febiger, Philadelphia, p. 459. Google Scholar2. Lyons C: Penicillin therapy of surgical infections in U. S. Army, J. A. M. A. 123: 1007, 1943. CrossrefGoogle Scholar3. KolodnyDenhoff MHE: Reactions in penicillin therapy, J. A. M. A. 130: 1058, 1946. CrossrefMedlineGoogle Scholar4. Kleinfeld L: Sequelae following oral and topical use of penicillin, New York State J. Med. 46: 915, 1946. MedlineGoogle Scholar5. MaceyHays HBTG: Allergic reactions to penicillin therapy, U. S. Nav. M. Bull. 45: 1143, 1945. MedlineGoogle Scholar6. Walley JF: Severe reactions after penicillin, Brit. M. J. 1: 150, 1948. CrossrefMedlineGoogle Scholar7. Maganzini HC: Anaphylactoid reaction to penicillins V and G administered orally, New England J. Med. 256: 52, 1957. CrossrefMedlineGoogle Scholar8. Madalin HE: Anaphylactoid reaction following use of penicillin lozenges, J. Michigan M. Soc. 53: 61, 1954. Google Scholar9. EisenstadterHussar DAE: Severe anaphylactic reaction from oral penicillin, Am. Pract. and Digest Treat. 5: 783, 1954. MedlineGoogle Scholar10. PetersHendersonPrickman GALLLE: Anaphylactic penicillin reactions, Proc. Staff Meet., Mayo Clin. 30: 634, 1955. MedlineGoogle Scholar11. de MelloMendes JFE: Rencão do tipo anafilatico após uma prova intradérmica com penicilina, Rev. Asoc. méd. brasil 2: 145, 1956. MedlineGoogle Scholar12. KernWimberley RANA: Penicillin reactions: their nature, growing importance, recognition, management and prevention, Am. J. M. Sc. 226: 357, 1953. CrossrefMedlineGoogle Scholar13. Chevallier R: L'oedème fugace de la région antropylorique au cours des gastropathies allergiques. Etude gastroscopique, Bronchoscop., oesophagoscop. et gastroscop. 2: 129, 1935. Google Scholar14. PollardStewart HMGJ: Experimental reproduction of gastric allergy in human beings with controlled observation on the mucosa, J. Allergy 13: 467, 1942. CrossrefGoogle Scholar15. Smith VM: Fatal reactions to penicillin: evaluation of a test for sensitivity, New England J. Med. 257: 447, 1957. CrossrefMedlineGoogle Scholar16. AfendulisGulzow TM: Die allergisch-hyperergische Gastritis. Tier experimentelle Untersuchungen, Ztschr. f. d. ges. exper. Med. 104: 167, 1938. CrossrefGoogle Scholar17. Schindler R: Gastroscopy: the endoscopic study of gastric pathology, 2nd Ed., 1950, University of Chicago Press, Chicago, pp. 254-256. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Philadelphia, Pennsylvania*Received for publication May 23, 1958.From the Department of Medicine, Temple University Medical Center, Philadelphia.Requests for reprints should be addressed to S. P. Bralow, M.D., Temple University Medical Center, 3400 North Broad Street, Philadelphia 40, Pennsylvania. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byRecurrent oedema of the small intestineDrug-Induced Gastrointestinal DisordersDrug-induced gastrointestinal diseasePENICILLIN ALLERGY: A REVIEW OF THE IMMUNOLOGICAL AND CLINICAL ASPECTSDRUG REACTIONS INVOLVING THE ALIMENTARY TRACTReferences 1 August 1959Volume 51, Issue 2Page: 384-390KeywordsAnaphylaxisEdemaGastroenterology and hepatologyHemorrhageMucous membranesNauseaPenicillinSurgeryUrticariaVomiting ePublished: 1 December 2008 Issue Published: 1 August 1959 PDF downloadLoading ...