A REFRACTORY CASE OF IDIOPATHIC STEATORRHEA (NON-TROPICAL SPRUE), WITH OBSERVATIONS ON THE THERAPEUTIC EFFECTS OF SALT-POOR HUMAN ALBUMIN AND OF THE ADRENOCORTICOTROPIC HORMONE
Authors: T P ALMY
Journal: Annals of Internal Medicine (1951)

Case Reports1 April 1951A REFRACTORY CASE OF IDIOPATHIC STEATORRHEA (NON-TROPICAL SPRUE), WITH OBSERVATIONS ON THE THERAPEUTIC EFFECTS OF SALT-POOR HUMAN ALBUMIN AND OF THE ADRENOCORTICOTROPIC HORMONETHOMAS P. ALMY, M.D.THOMAS P. ALMY, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-34-4-1041 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTreatment of cases of tropical sprue by means of diet, vitamin supplements, and liver extract, folic acid, or vitamin B12is considered to be satisfactory in the great majority of cases. In the closely related syndrome of idiopathic steatorrhea (nontropical sprue), these measures are often inadequate to bring on a remission, and occasionally a patient with this disorder will become progressively worse despite well-directed and intensive therapy. In such a resistant case, we have been led to administer concentrated human albumin, and subsequently ACTH, with favorable results. This report is concerned with the description of these therapeutic effects, and with...Bibliography1. LopezMilanesSpiesTocaAramburuLopez GFTDRLTH: The association of hypoproteinemia with severe tropical sprue, Am. J. M. Sc. 218: 660, 1949. CrossrefMedlineGoogle Scholar2. VerzárMcDougall FEJ: Absorption from the intestine, 1936, Longmans, London. Google Scholar3. Bavetta LA: The effect of adrenalectomy on the absorption of the short chain fatty acids and their triglycerides, Am. J. Physiol. 140: 44, 1943. CrossrefGoogle Scholar4. AlthausenAndersonStockholm TLEMM: Effect of adrenalectomy and of NaCl on intestinal absorption of dextrose, Proc. Soc. Exper. Biol. and Med. 40: 342, 1939. CrossrefGoogle Scholar5. Marrazzi R: The influence of adrenalectomy and of fasting on the intestinal absorption of carbohydrates, Am. J. Physiol. 131: 36, 1940. CrossrefGoogle Scholar6. BarnesWickMillerMacKay RHANESEM: Effect of adrenalectomy on rate of fat absorption, Proc. Soc. Exper. Biol. and Med. 40: 651, 1939. CrossrefGoogle Scholar7. ThornForshamFrawleyHillRocheStaehlinWilson GWPHTFSRMDDL: The clinical usefulness of ACTH and cortisone, New England J. Med. 242: 865, 1950. CrossrefMedlineGoogle Scholar8. PaniaguaCasasHernandez-Morales MECBF: Studies on adrenal function in sprue: preliminary report, J. Clin. Endocrinol. 10: 939, 1950. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Received for publication November 3, 1950.From the Department of Medicine, the New York Hospital-Cornell Medical Center. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byObservations on oral betamethasone-17-valerate in the treatment of idiopathic steatorrhoea.THE XYLOSE TOLERANCE TEST AS A MEASURE OF THE INTESTINAL ABSORPTION OF CARBOHYDRATE IN SPRUE*†J. M. FINLAY, M.D., F.R.C.P.(C), K. J. R. WIGHTMAN, M.D., F.R.C.P.(C), F.A.C.P.Long-term or maintenance adrenal steroid therapy in non-tropical sprueClinical and histological observations in fatal non-tropical sprueThe Use of ACTH and Adrenocorticosteroids in Diseases of the Digestive SystemA Wheat-, Rye-, and Oat-Free Diet . Treatment of Non-Tropical SprueThe Effect of a Gluten-Free Diet on Fat, Nitrogen, Mineral Metabolism in Patients with SpruePreviously Undescribed Clinical and Postmortem Observations in Non-Tropical Sprue: Possible Role of Prolonged Corticosteroid TherapyMODERN TREATMENT OF THE MALABSORPTION SYNDROME IN ADULTS*JOHN M. FINLAY, M.D., F.R.C.P.(C), KEITH J. R. WIGHTMAN, M.D., F.R.C.P.(C), F.A.C.P.Effect of ACTH and Cortisone on Fat Absorption in Steatorrhea of Various CausesCorrection of the Anemia of Malabsorption Syndrome (Nontropical Sprue?) by Oral Administration of Cortisone and IronMalabsorption syndromePharmacologic Aspects of Adrenocortical Steroids and ACTH in Man 1 April 1951Volume 34, Issue 4Page: 1041-1048KeywordsAdrenocorticotropic hormoneAlbuminsDietFolic acidLiver ePublished: 1 December 2008 Issue Published: 1 April 1951 PDF downloadLoading ...