ELECTROCARDIOGRAPHIC CHANGES DURING HEMODIALYSIS, WITH OBSERVATIONS ON CONTRIBUTION OF ELECTROLYTE DISTURBANCES TO DIGITALIS TOXICITY
Authors: R M KOHN, J E KILEY
Journal: Annals of Internal Medicine (1953)

Article1 July 1953ELECTROCARDIOGRAPHIC CHANGES DURING HEMODIALYSIS, WITH OBSERVATIONS ON CONTRIBUTION OF ELECTROLYTE DISTURBANCES TO DIGITALIS TOXICITYROBERT M. KOHN, M.D., JOHN E. KILEY, M.D.ROBERT M. KOHN, M.D., JOHN E. KILEY, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-39-1-38 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptExtracorporeal hemodialysis is often lifesaving in the treatment of acute renal insufficiency, but the procedure itself is not without danger. Heparinization may be accompanied by hemorrhage; the patient may accidentally undergo in a short period of time a net gain or loss of blood volume from or into the machine1; elevation of blood pressure may occur,2and cardiac arrhythmias may be produced. In the course of observations on these cardiovascular changes during 13 consecutive hemodialyses with a Kolff type dialyzer at the Albany Hospital, electrocardiographic changes were noted in 11 instances and arrhythmias in three. It was felt that such...Bibliography1. WolfRempKileyCurrie AVDGJEGD: Artificial kidney function: kinetics of hemodialysis, J. Clin. Investigation 30: 1062, 1951. CrossrefMedlineGoogle Scholar2. MerrillGoodaleSwan JPWTRC: Observations on the pressor response occurring during dialysis with the artificial kidney (abst.), J. Clin. Investigation 30: 660, 1951. Google Scholar3. Wolf AV: The artificial kidney, Science 115: 193, 1952. CrossrefMedlineGoogle Scholar4. LarsonGreenberg CEDM: The analysis of calcium in blood and other biological material by titration with ceric sulfate, J. Biol. Chem. 123: 199, 1938. CrossrefGoogle Scholar5. MerrillLevineSomervilleSmith JPHDWS: Clinical recognition and treatment of acute potassium intoxication, Ann. Int. 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Pharmacol. and Exper. Therap. 96: 372, 1949. MedlineGoogle Scholar30. SmithWinklerHoff PKAWHE: Calcium and digitalis synergism, Arch. Int. Med. 64: 322, 1939. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication February 3, 1953.From the Department of Medicine, Albany Medical College and Albany Hospital, Albany, N. Y.This work was done while Dr. Kiley was Research Fellow in Medicine of the American College of Physicians, 1951-52, and Dr. Kohn was a Fellow of the National Heart Institute. 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