OBSERVATIONS ON THE SUSCEPTIBILITY OF PNEUMOCOCCI TO SULFAPYRIDINE, SULFATHIAZOLE AND SULFAMETHYLTHIAZOLE
Authors: Francis C. Lowell, Elias Strauss, Maxwell Finland
Journal: Annals of Internal Medicine (1940)

Article1 December 1940OBSERVATIONS ON THE SUSCEPTIBILITY OF PNEUMOCOCCI TO SULFAPYRIDINE, SULFATHIAZOLE AND SULFAMETHYLTHIAZOLEFRANCIS C. LOWELL, ELIAS STRAUSS, MAXWELL FINLAND, F.A.C.P.FRANCIS C. LOWELLSearch for more papers by this author, ELIAS STRAUSSSearch for more papers by this author, MAXWELL FINLAND, F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-14-6-1001 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptStrains of pneumococci have been shown to vary in their susceptibility to the action of the same sulfonamide drugs both in vitro1-4and in therapeutic experiments in vivo.1, 5These differences in susceptibility have been noted among strains of the same type6and among different types.1-5Resistance to the action of sulfapyridine has been induced in previously susceptible strains both in vitro7and in animals experimentally infected and treated with subeffective amounts of drugs.1In this paper is presented a study of the in vitro susceptibility to sulfapyridine, sulfathiazole and sulfamethylthiazole of pneumococci isolated from patients undergoing treatment with either...Bibliography1. 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Author, Article, and Disclosure InformationAffiliations: Boston, Massachusetts*Received for publication June 19, 1940.From the Thorndike Memorial Laboratory, Second and Fourth Medical Services (Harvard), Boston City Hospital, and the Department of Medicine, Harvard Medical School, Boston.The study was carried out with the technical assistance of Mildred W. Barnes and Clare Wilcox. The chemical determinations were made by Elizabeth S. Smith and Louise Sheldon. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPneumococcal InfectionsPneumococcal InfectionsPneumococcal InfectionsPneumococcal InfectionsAntibacterial Chemotherapy with SulfonamidesDie Resistenzbildung bei MikroorganismenDie PneumonienBacterial Sensitivity Tests In The Treatment Of Chronic External Ocular Infections*The Inheritance of Environmentally Induced Characters in BacteriaCorrelation of in vitro Sulfonamide Resistance of the Gonococcus with Results of Sulfonamide Therapy 1 December 1940Volume 14, Issue 6Page: 1001-1023KeywordsDrugsHospital medicineMedical servicesPatientsResearch laboratoriesSulfonamide Issue Published: 1 December 1940 PDF downloadLoading ...