CEREBRAL COMPLICATIONS OF HYPOTENSION
Authors: J F FAZEKAS, J KLEH, A E PARRISH
Journal: Annals of Internal Medicine (1955)

Article1 July 1955CEREBRAL COMPLICATIONS OF HYPOTENSIONJOSEPH F. FAZEKAS, M.D., JACK KLEH, M.D., ALVIN E. PARRISH, M.D.JOSEPH F. FAZEKAS, M.D.Search for more papers by this author, JACK KLEH, M.D.Search for more papers by this author, ALVIN E. PARRISH, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-43-1-165 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptReversible functional disturbances, localized infarctions and permanent loss of function of the higher centers are complications that may result from varying degrees of cerebral vascular insufficiency induced by hypotension. Cerebral arteriosclerosis may also predispose to similar disturbances. This is understandable since in both conditions the rate of cerebral blood flow may be reduced to values below that compatible with normal cellular activity. When hypotension and cerebral vascular disease coexist, cerebral complications are more likely to occur, since their effects may be additive. Since it is practically impossible to determine the extent of cerebral arteriosclerosis, it can be anticipated that with...Bibliography1. AlmanRosenbergFazekas RWMJF: Effects of histamine on cerebral hemodynamics and metabolism, Arch. Neurol. and Psychiat. 67: 354, 1952. CrossrefGoogle Scholar2. FinnertyWitkinFazekas FALJF: Cerebral hemodynamics during cerebral ischemia induced by acute hypotension, J. Clin. Investigation 33: 1227, 1954. CrossrefMedlineGoogle Scholar3. KetySchmidt SSCF: Nitrous oxide method for quantitative determination of cerebral blood flow in man: theory, procedure and normal values, J. Clin. Investigation 27: 476, 1948. CrossrefMedlineGoogle Scholar4. AlmanFazekas RWJF: Apparatus for continuous blood-pressure observation, New England J. Med. 248: 105, 1953. CrossrefMedlineGoogle Scholar5. Smirk FH: The management of hypertension with special reference to the methonium compounds. Television symposium on the management of hypertension, made possible through Wyeth Laboratories, Philadelphia, Pa., September 23, 1954, p. 6. Google Scholar6. HicksWarren SPS: Infarction of the brain without thrombosis: an analysis of 100 cases with autopsy, Arch. Path. 52: 403, 1951. Google Scholar7. Denny-Brown D: The treatment of recurrent cerebrovascular symptoms and the question of "vasospasm," M. Clin. North America 35: 1457, 1951. CrossrefMedlineGoogle Scholar8. CordayRothenbergPutnam ESFTJ: Cerebral vascular insufficiency, Arch. Neurol. and Psychiat. 69: 551, 1953. CrossrefGoogle Scholar9. FazekasKlehParrish JFJAE: The influence of shock on cerebral hemodynamics and metabolism, Am. J. M. Sc., in press. Google Scholar10. Adler FH: Physiology of the eye. Clinical application, 1950, C. V. Mosby Company, St. Louis, pp. 438-439. Google Scholar11. WeinbergerGibbonGibbon LMMHJH: Temporary arrest of circulation to central nervous system: pathologic effects, Arch. Neurol. and Psychiat. 43: 961, 1940. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Washington, D. C.*Received for publication December 18, 1954.From the George Washington and Georgetown University Medical Divisions, District of Columbia General Hospital, Washington, D. C.This investigation was supported by a research grant (PHS B-178) from the National Institute of Neurological Diseases and Blindness of the National Institutes of Health, Public Health Service, and by a research grant from the United Cerebral Palsy Foundation. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAcute controlled hypotension and EEG in patients with hypertension and cerebrovascular diseaseCEREBRAL BLOOD CIRCULATION IN DEMENTIATherapeutic modalities in the management of cerebral vascular insufficiencyCerebral Complications in Nitroglycerine Treatment of Angina PectorisTotal Cerebral Blood Flow and Oxygen Consumption Using the Dye-Dilution MethodOPHTHALMODYNAMOMETRY IN CAROTID ARTERY DISEASEAcute Cerebral InfarctSPONTANEOUS CEREBRAL HAEMORRHAGE AND ENCEPHALOMALACIA. A Clinico-Pathological Study of 263 Cases with Special Reference to Cardiovascular Diseases and Cerebral Atherosclerosis 1 July 1955Volume 43, Issue 1Page: 165-172KeywordsCerebral palsyHealth services researchHypotensionInfarctionIschemiaMedical servicesPrevention, policy, and public healthResearch grantsVascular diseasesVascular insufficiency ePublished: 1 December 2008 Issue Published: 1 July 1955 PDF downloadLoading ...