Update in General Internal Medicine
Authors: Catherine Reinis Lucey
Journal: Annals of Internal Medicine (2002)

Updates from the Annual Session3 September 2002Update in General Internal MedicineCatherine Reinis Lucey, MD and Carmella A. Cole, MDCatherine Reinis Lucey, MDFrom Washington Hospital Center, Washington, D.C.Search for more papers by this author and Carmella A. Cole, MDFrom Washington Hospital Center, Washington, D.C.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-137-5_Part_1-200209030-00009 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail This Update in General Internal Medicine examines the topics that we thought were most interesting to the practicing general internist. We address new lessons learned in the previous year about secondary prevention in cardiovascular disease, the management of systolic dysfunction, the specific choice of antihypertensive agents for special populations, the significance of Helicobacter pylori infection, the management of thromboembolic disease, and finally, the use of estrogen replacement therapy.Secondary Prevention of Cardiovascular EventsAtorvastatin Decreases the Risk for Early Recurrence of Ischemia in Patients Who Have Recently Experienced an Acute Coronary Syndrome ...References1. . Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group. N Engl J Med. 1998;339:1349-57. [PMID: 9841303] CrossrefMedlineGoogle Scholar2. . Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet. 1994;344:1383-9. [PMID: 7968073] MedlineGoogle Scholar3. Sacks FM, Pfeffer MA, Moye LA, Rouleau JL, Rutherford JD, Cole TG, et al . The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigators. N Engl J Med. 1996;335:1001-9. [PMID: 8801446] CrossrefMedlineGoogle Scholar4. Stenestrand U, Wallentin L. Early statin treatment following acute myocardial infarction and 1-year survival. JAMA. 2001;285:430-6. [PMID: 11242427] CrossrefMedlineGoogle Scholar5. Aronow HD, Topol EJ, Roe MT, Houghtaling PL, Wolski KE, Lincoff AM, et al . Effect of lipid-lowering therapy on early mortality after acute coronary syndromes: an observational study. Lancet. 2001;357:1063-8. [PMID: 11297956] CrossrefMedlineGoogle Scholar6. Hennekens CH, Ridker PM, eds. Clinical Trials in Cardiovascular Disease: A Companion to Braunwald's Heart Disease. Philadelphia: WB Saunders; 1999:206. Google Scholar7. . Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. The SOLVD Intestigators. N Engl J Med. 1991;325:293-302. CrossrefMedlineGoogle Scholar8. . Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions. The SOLVD Investigators. N Engl J Med. 1992;327:685-91. [PMID: 1463530] CrossrefMedlineGoogle Scholar9. Carson P, Ziesche S, Johnson G, Cohn JN. Racial differences in response to therapy for heart failure: analysis of the vasodilator-heart failure trials. Vasodilator-Heart Failure Trial Study Group. J Card Fail. 1999;5:178-87. [PMID: 10496190] CrossrefMedlineGoogle Scholar10. U.S. Renal Data System. USRDS 1999 Annual Data Report. Bethesda, MD: National Institutes of Health, National Institute of Diabetes, Digestive, and Kidney Disease; 1999. Google Scholar11. Brenner BM, Cooper ME, de Zeeuw D, Keane WF, Mitch WE, Parving HH, et al . Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med. 2001;345:861-9. [PMID: 11565518] CrossrefMedlineGoogle Scholar12. Parving HH, Lehnert H, Bröchner-Mortensen J, Gomis R, Andersen S, Arner P, et al . The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes. N Engl J Med. 2001;345:870-8. [PMID: 11565519] CrossrefMedlineGoogle Scholar13. Schwarz T, Schmidt B, Höhlein U, Beyer J, Schröder HE, Schellong SM. Eligibility for home treatment of deep vein thrombosis: prospective study. BMJ. 2001;322:1212-3. [PMID: 11358773] CrossrefMedlineGoogle Scholar14. Dunn AS, Schechter C, Gotlin A, Vomvolakis D, Jacobs E, Sacks HS, et al . Outpatient treatment of deep venous thrombosis in diverse inner-city patients. Am J Med. 2001;110:458-62. [PMID: 11331057] CrossrefMedlineGoogle Scholar15. Stampfer MJ, Colditz GA. Estrogen replacement therapy and coronary heart disease: a quantitative assessment of the epidemiologic evidence. Prev Med. 1991;20:47-63. [PMID: 1826173] CrossrefMedlineGoogle Scholar16. Psaty BM, Smith NL, Lemaitre RN, Vos HL, Heckbert SR, LaCroix AZ, et al . Hormone replacement therapy, prothrombotic mutations, and the risk of incident nonfatal myocardial infarction in postmenopausal women. JAMA. 2001;285:906-13. [PMID: 11180734] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Washington Hospital Center, Washington, D.C.Corresponding Author: Carmella A. Cole, MD, Division of General Internal Medicine, Washington Hospital Center, 110 Irving Street, NW, Room 1A-50, Washington, DC 20010.Current Author Addresses: Dr. Lucey: Department of Medicine, Washington Hospital Center, 110 Irving Street, NW, Room 2A-64, Washington, DC 20010.Dr. Cole: Division of General Internal Medicine, Washington Hospital Center, 110 Irving Street, NW, Room 1A-50, Washington, DC 20010. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 3 September 2002Volume 137, Issue 5_Part_1Page: 334-340KeywordsACE inhibitorsAspirinBlood pressureCholesterolHeart failureHemorrhageLow density lipoproteinMortalityMyocardial infarctionRenal failure ePublished: 3 September 2002 Issue Published: 3 September 2002 Copyright & PermissionsCopyright © 2002 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...