SALMONELLA TYPHIMURIUM OSTEOMYELITIS WITH SICKLE CELL-HEMOGLOBIN C DISEASE: A REVIEW AND CASE REPORT
Authors: A L WIDEN, L CARDON
Journal: Annals of Internal Medicine (1961)

Case Reports1 March 1961SALMONELLA TYPHIMURIUM OSTEOMYELITIS WITH SICKLE CELL-HEMOGLOBIN C DISEASE: A REVIEW AND CASE REPORTARNOLD L. WIDEN, M.D., LEONARD CARDON, M.D., F.A.C.P.ARNOLD L. WIDEN, M.D.Search for more papers by this author, LEONARD CARDON, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-54-3-510 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe interesting observation has been made1-10 that salmonella osteomyelitis develops more frequently in patients with sickle-hemoglobinopathies than can be accounted for merely on the basis of chance occurrence.Osteomyelitis is not a common complication of salmonella infections, since only 0.82% of cases of typhoid fever and 0.2% of paratyphoid infections develop skeletal involvement.11-15 Of 3,000 cases of salmonella infections (excluding Salmonella typhosa) bacteriologically identified by the New York Salmonella Center, only five cultures were obtained from cases of osteomyelitis—three due to Salmonella typhimurium, and one each due to Salmonella enteritidis and Salmonella panama.16, 17In a review of salmonella osteomyelitis...Bibliography1. RobertsHilburg ARLE: Sickle cell disease with salmonella osteomyelitis. J. Pediat. 52: 170, 1958. CrossrefMedlineGoogle Scholar2. Editorial: Sickle cells and salmonellae. Brit. Med. J. 2: 1537, 1957. Google Scholar3. HookCampbellWeensCooper EWCGHSGR: Salmonella osteomyelitis in patients with sickle cell anemia. New Engl. J. Med., 257: 403, 1957. CrossrefMedlineGoogle Scholar4. SilverSimonClement HKJLDH: Salmonella osteomyelitis and abnormal hemoglobin disease. Pediatrics 20: 439, 1957. MedlineGoogle Scholar5. HughesCarroll JGDS: Salmonella osteomyelitis complicating sickle cell disease. Pediatrics 19: 184, 1957. MedlineGoogle Scholar6. VandepitteVan Oye JE: Salmonella osteomyelitis. Lancet 1: 966, 1956. CrossrefGoogle Scholar7. VandepitteColaertLambotte-LegrandLambotte-LegrandPerin JJJCF: Les osteites a salmonella chez les sickleanemiques. A propos de 5 observations. Ann. Soc. Belg. Méd. Trop. 33: 511, 1953. Google Scholar8. Smith WE: Sickle cell anemia and salmonella osteomyelitis. Ohio Med. J. 49: 692, 1953. MedlineGoogle Scholar9. Lambotte-LegrandLambotte-Legrand JC: L'anemie a hematies falciformes chez l'enfant indigene du bas-Congo. Mem. Inst. Roy. Belge, 1951, Brussels, cited by editorial in Brit. Med. J. 2: 1537, 1957. Google Scholar10. HoltHodges JFFJ, Editors: The 1951 Yearbook of Radiology, p. 88. The Year Book Publishers, Inc., Chicago, 1951. Google Scholar11. Murphy JB: Bone and joint disease in relation to typhoid fever. Surg., Gynec., Obstet. 23: 119, 1916. Google Scholar12. Winslow N: Typhoidal osteomyelitis. Ann. Surg. 77: 319, 1923. CrossrefMedlineGoogle Scholar13. VealMcFetridge JREM: Paratyphoid osteomyelitis: a report of two additional cases. J. Bone Joint Surg. 32: 445, 1934. Google Scholar14. GiaccaiIdriss LH: Osteomyelitis due to salmonella infections. J. Pediat. 41: 73, 1952. CrossrefMedlineGoogle Scholar15. Veal JR: Typhoid and paratyphoid osteomyelitis. Amer. J. Surg. 43: 594, 1939. CrossrefGoogle Scholar16. SeligmannSaphraWasserman EIM: Salmonella infections in man. An analysis of 1000 cases bacteriologically identified by the New York Salmonella Center. Amer. J. Hyg. 38: 226, 1943. Google Scholar17. SeligmannSaphraWasserman EIM: Salmonella infections in the U. S. A. A second series of 2000 human infections recorded by the New York Salmonella Center. J. Immun. 54: 69, 1946. MedlineGoogle Scholar18. TraismanChamplin HSG: Salmonella typhimurium osteomyelitis. J. Pediat. 38: 244, 1951. CrossrefMedlineGoogle Scholar19. Goldenberg IS: Sickle-cell anemia, Salmonella enteritidis osteomyelitis, and remote postoperative wound abscess. Surgery 38: 758, 1955. MedlineGoogle Scholar20. WhiteMeynell GMJ: Paratyphoid C osteomyelitis of the tibia. Lancet 1: 362, 1956. CrossrefGoogle Scholar21. Harvey AM: Salmonella suipestifer infection in human beings. Review of the literature and report of twenty-one new cases. Arch. Intern. Med. 59: 118, 1937. CrossrefGoogle Scholar22. GajzagoGottche DO: Salmonella suipestifer infections in childhood. J. Dis. Child. 63: 15, 1942. Google Scholar23. GoulderKingslandJanesway NEMFCA: Salmonella suipestifer infection in Boston. A report of eleven cases, with autopsy findings in a case of bacterial endocarditis due to this organism, and a study of the agglutination reactions in this infection. New Engl. J. Med. 226: 127, 1942. CrossrefGoogle Scholar24. JonesLee JAHF: Salmonella suipestifer infections in children. A report of eighteen cases. Amer. J. Med. Sci. 211: 723, 1946. CrossrefMedlineGoogle Scholar25. Self EB: Acute hematogenous osteomyelitis. Pediatrics 1: 617, 1948. MedlineGoogle Scholar26. DiggsPulliamKing LWHNJC: The bone changes in sickle cell anemia. Southern Med. J. 30: 249, 1937. CrossrefGoogle Scholar27. SmithConley EWCL: Clinical features of the genetic variants of sickle cell disease. Bull. Johns Hopkins Hosp. 94: 289, 1954. MedlineGoogle Scholar28. Smith WS: Sickle cell anemia and salmonella osteomyelitis. Ohio Med. J. 49: 692, 1953. MedlineGoogle Scholar29. EhrenpreisSchwinger BHN: Sickle cell anemia. Amer. J. Roentgenol. 68: 28, 1952. Google Scholar30. Caffey J: The skeletal changes in the chronic hemolytic anemias (erythroblastic anemia, sickle cell anemia, and chronic hemolytic icterus). Amer. J. Roentgenol. 37: 293, 1937. Google Scholar31. CarringtonDavison GLWC: Multiple osteomyelitis due to Bacillus paratyphosus B. Bull. Johns Hopkins Hosp. 36: 428, 1925. Google Scholar32. MyersonHarrisonLohmuller RMEHW: Incidence and significance of abnormal hemoglobins. Amer. J. Med. 26: 543, 1959. CrossrefMedlineGoogle Scholar33. Seidenstein H: Salmonella osteomyelitis. Bull. Hosp. Joint Dis. 6: 126, 1945. MedlineGoogle Scholar34. Burch JE: Paratyphoid osteomyelitis—a case report. Southern Med. J. 42: 138, 1949. CrossrefMedlineGoogle Scholar35. WighThompson RHJ: Cortical fissuring in osteomyelitis complicating sickle-cell anemia. Radiology 55: 553, 1950. CrossrefMedlineGoogle Scholar36. MayerPohlidal VSJ: Salmonella osteomyelitis with concomitant sickle cell anemia. New York J. Med. 51: 2785, 1951. MedlineGoogle Scholar37. Zuelzer WW: Personal communication, quoted by Smith.28 Google Scholar38. EllenbogenRaimGrossman NCJL: Salmonella species (type montevideo) osteomyelitis. J. Dis. Child. 90: 275, 1955. MedlineGoogle Scholar39. ChoremisYannakosBonta VKDC: Falla von auggedehnter osteomyelitis bei sichelzellanamie. Hel. Paediat. Acta 10: 478, 1955. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication November 20, 1959.From the Department of Medicine, Northwestern University of Medical School, and Northwestern Division, Cook County Hospital, Chicago, Illinois.Requests for reprints should be addressed to Arnold L. Widen, M.D., Department of Medicine, Evanston Hospital Association, 2650 North Ridge Avenue, Evanston, Illinois. 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