RECENT ADVANCES IN THE PATHOGENESIS AND TREATMENT OF ATHEROSCLEROSIS
Authors: G E WAKERLIN
Journal: Annals of Internal Medicine (1952)

Article1 August 1952RECENT ADVANCES IN THE PATHOGENESIS AND TREATMENT OF ATHEROSCLEROSISG. E. WAKERLIN, Ph.D., M.D., F.A.C.P.G. E. WAKERLIN, Ph.D., M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-37-2-313 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAtherosclerosis is one form of arteriosclerosis. Arteriosclerosis is a condition involving thickening of the arterial wall, accumulation of lipid substances, and degenerative changes with calcium deposition, distortion and loss of elasticity. There are generally considered to be several varieties or forms of arteriosclerosis. Atherosclerosis is the term applied to the thickening of the intima by plaque formation resulting from the deposition of cholesterol and lipids and the laying down of new connective tissue. Atherosclerosis involves especially the large conducting, elastic arteries, such as the aorta, but also smaller arteries, such as the coronaries and the cerebrals. Medial or Mönckeberg's sclerosis...Bibliography General References1. RoenTownsendPerry PBEWJW: Heredity in arteriosclerosis, Circulation 4: 471, 1951. Google Scholar2. Cullumbine H: Cardiovascular disease in Ceylon, Trans. Fifth Conference on Factors Regulating Blood Pressure, 1951, Josiah Macy, Jr. Foundation, New York, p. 124. Google Scholar3. DedichenStromAdelsten-JensenCloss JARK: Incidence of atherosclerotic disease during war years, Trans. Fifth Conference on Factors Regulating Blood Pressure, 1951, Josiah Macy, Jr. Foundation, New York, p. 117. Google Scholar4. GertlerGarnLerman MMSMJ: The interrelationships of serum cholesterol, cholesterol esters and phospholipids in health and in coronary artery disease, Circulation 2: 205, 1950. CrossrefMedlineGoogle Scholar5. 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To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication January 30, 1952.From the Department of Physiology, University of Illinois College of Medicine.†The hypertension and atherosclerosis research group, headed by Dr. Wakerlin, is presently supported by grants from the United States Public Health Service (Grants H-428-C2 and H-423-C2), the American (Youngstown) Heart Association, the Chicago Heart Association, and the University of Illinois Foundation. 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Effect of lipotropic agents on serum lipid partitions in fifty patients with generalized atherosclerosis: A three year studyRECENT CONCEPTS OF THE PATHOGENESIS OF ATHEROSCLEROSIS 1 August 1952Volume 37, Issue 2Page: 313-322KeywordsArteriesAtherosclerosisConnective tissueCoronary arteriesHeartHypertensionLipidsMedical servicesPathogenesisStable coronary artery disease ePublished: 1 December 2008 Issue Published: 1 August 1952 PDF downloadLoading ...