THE CLINICAL MANIFESTATIONS OF SICKLE CELL ANEMIA
Authors: V GROVER
Journal: Annals of Internal Medicine (1947)

Article1 June 1947THE CLINICAL MANIFESTATIONS OF SICKLE CELL ANEMIAVICTOR GROVER, M.D., F.A.C.P.VICTOR GROVER, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-26-6-843 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn 1910 J. B. Herrick1first reported the association of sickle shaped erythrocytes with severe anemia and certain clinical symptoms now recognized as the clinical entity termed sickle cell anemia. In 1923 and 1924 Sydenstricker2, 3and Huck4pointed out its relative frequency. There have been many subsequent articles concerning various features of this disease, but it was thought worthwhile to report the general clinical manifestations as observed in the present series of cases. During the period January, 1936 to January, 1946 there were 48 cases of active sickle cell anemia treated in the medical wards of Kings County Hospital....Bibliography1. HERRICK JB: Peculiar elongated and sickle-shaped red blood corpuscles in a case of severe anemia, Arch. Int. Med., 1910, vi, 517-521. CrossrefGoogle Scholar2. SYDENSTRICKERMULHESINHOUSEAL VPWARW: Sickle cell anemia, Am. Jr. Dis. Child., 1923, xxvi, 132-154. CrossrefGoogle Scholar3. SYDENSTRICKER VP: Further observations on sickle cell anemia, Jr. Am. Med. Assoc., 1924, lxxxiii, 12-16. CrossrefGoogle Scholar4. HUCK JG: Sickle cell anemia, Bull. Johns Hopkins Hosp., 1923, xxiv, 335-344. Google Scholar5. CAMPBELL EH: Acute abdominal pain in anemia, Arch. Surg., 1935, xxxi, 607-621. CrossrefGoogle Scholar6. WERTHAMMITCHELLANGRIST FNA: The brain in sickle cell anemia, Arch. Neurol. and Psychiat., 1942, xlvii, 752-767. CrossrefGoogle Scholar7. CONNELL JH: Cerebral necrosis in sickle cell disease, Jr. Am. Med. Assoc., 1942, cxviii, 893-895. CrossrefGoogle Scholar8. ARENA JM: Cerebral vascular lesions accompanying anemia, Jr. Pediat., 1939, xiv, 745-751. CrossrefGoogle Scholar9. HUGHESDIGGSGILLESPIE JGLMCE: The involvement of the nervous system in sickle cell anemia, Jr. Pediat., 1940, xvii, 166-184. CrossrefGoogle Scholar10. PHILLIPS AA: Priapism. Report of a case associated with sickle cell anemia, Jr. Nat. Med. Assoc., 1944, xxxvi, 88-89. Google Scholar11. GETZOFF PL: Priapism and sickle cell anemia, a report of 3 cases, Jr. Urol., 1942, xlviii, 407-411. CrossrefGoogle Scholar12. DAWSON GR: Priapism, report of five cases. Two cases occurring with sickle cell anemia, Jr. Urol., 1939, xlii, 821-828. CrossrefGoogle Scholar13. KOBAKSTEINDARO AJPJAF: Sickle cell anemia in pregnancy. A review of the literature and report of six cases, Am. Jr. Obst. and Gynec., 1941, xli, 811-823. CrossrefGoogle Scholar14. KLINEFELTER HF: Heart in anemia, Am. Jr. Med. Sci., 1942, cciii, 34-51. CrossrefGoogle Scholar15. KINGJANEWAY JTCA: Sickle cell anemia with cardiac complications, Internat. Clin., 1937, iii, 41-46. Google Scholar16. HARDEN AS: Sickle cell anemia. Changes in the vessels and in the bones, Am. Jr. Dis. Child., 1937, liv, 1045-1051. CrossrefGoogle Scholar17. CAFFEY J: Skeletal changes in chronic hemolytic anemias, Am. Jr. Roentgenol., 1937, xxxvii, 293-324. Google Scholar18. SCHAEFER BF: Sickle cell anemia and cholelithiasis. Report of a case, Med. Ann. District of Columbia, 1942, xi, 392-396. Google Scholar19. RYERSONTERPLAN CSKL: Sickle cell anemia. Two unusual cases with autopsy, Folia haemat., 1935, liii, 353-369. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Brooklyn, New York*Received for publication April 4, 1946. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPriapism as a Complication of Sickle Cell DiseaseInfections in Sickle Cell DiseasePain in prelingual children and its evaluation by pain-induced vocalizationInhibitor of in Vitro Neutrophil Migration in Sera of Children with Homozygous Sickle Cell Gene during Pain CrisisCase report bland cholestasisPriapismCholelithiasis in sickle cell anemiaSickle Cell Disease and Viral HepatitisELIZABETH BARRETT-CONNOR, M.D.Cholestasis in sickle cell anemiaPriapism Associated with Sickle Cell DiseaseSickle-cell anemia in pregnancySplenomegaly in sickle cell anemiaLiver disease in sickle cell anemiaPriapism in sickle Cell AnemiaStudies in sickle-cell anemiaSickle cell anemiaSICKLE CELL ANEMIA AND CARCINOMA OF THE BREAST COMPLICATED BY PREGNANCY*FERDINAND FETTER, M.D., F.A.C.P., JOHN C. HOWELL, M.D. 1 June 1947Volume 26, Issue 6Page: 843-851KeywordsAnemia ePublished: 1 December 2008 Issue Published: 1 June 1947 PDF downloadLoading ...