NEOPLASTIC INVASION OF THE HEART AND PERICARDIUM
Authors: G U COHEN, T M PERRY, J M EVANS
Journal: Annals of Internal Medicine (1955)

Article1 June 1955NEOPLASTIC INVASION OF THE HEART AND PERICARDIUMGENE U. COHEN, M.D., THOMAS M. PEERY, M.D., JOHN M. EVANS, M.D.GENE U. COHEN, M.D., THOMAS M. PEERY, M.D., JOHN M. EVANS, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-42-6-1238 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIt is the purpose of this report to call attention to the frequency of neoplastic invasion of the heart and pericardium and to present the clinical features which may facilitate antemortem diagnosis. The observations are derived from a clinicopathologic study of 315 deaths from malignant tumors in a series of 1,007 consecutive autopsies at this hospital, and from a partial review of the medical literature.FREQUENCY AND NATURE OF CARDIAC METASTASESThe incidence of cardiac metastases has been variously reported to be from 0.24 to 6.45%1-3, 22 of all autopsies, as compared to an incidence of 0.0017% for primary tumors...Bibliography1. PolliaGogol JALJ: Some notes on malignancy of the heart, Am. J. Cancer 27: 329-333, 1936. CrossrefGoogle Scholar2. ScottGarvin RWCF: Tumors of the heart and pericardium, Am. Heart J. 17: 431-436, 1939. CrossrefGoogle Scholar3. Dimmette RM: The antemortem diagnosis of secondary tumors of the heart; report of 4 cases, U. S. Armed Forces M. J. 1: 750-758, 1950. MedlineGoogle Scholar4. Friedberg CK: Diseases of the heart, 1st Ed., 1949, W. B. Saunders Co., Philadelphia, p. 995. Google Scholar5. Willis RA: The spread of tumors in the human body, 1934, J. & A. Churchill, Ltd., London, p. 259. Google Scholar6. Burke EM: Metastatic tumors of the heart, Am. J. Cancer 20: 33-47, 1934. CrossrefGoogle Scholar7. Prichard RW: Tumors of the heart; review of the subject and report of 150 cases, Arch. Path. 51: 1, 98-128, 1951. Google Scholar8. BiselWroblewskiLaDue HFFJS: Incidence and clinical manifestations of cardiac metastasis, J. A. M. A. 153: 712-715, 1953. CrossrefMedlineGoogle Scholar9. Pfeiffer MC: Neoplasms of the heart, Am. Med. Women's A. 6: 293-296, 1951. MedlineGoogle Scholar10. Pfeiffer MC: A summary of cardiac neoplasms, Postgrad. Med. 11: 438, 1952. CrossrefGoogle Scholar11. CollerInkleyMoragues FCJJV: Neoplastic endocardial implants; report of a case, Am. J. Clin. Path. 20: 159-164, 1950. CrossrefMedlineGoogle Scholar12. SiegelYoung MLAM: Electrocardiographic findings in tumors of the heart with report of a case, Am. Heart J. 8: 682-690, 1933. CrossrefGoogle Scholar13. RavidSachs JMJ: Tumors of the heart with a report of a primary fibromyxosarcoma of the left auricle and the pulmonary vein associated with multiple tumors of the mesentery and alimentary tract, Am. Heart J. 26: 385-397, 1943. CrossrefGoogle Scholar14. Shelburne PA: Primary tumors of the heart with special reference to certain features which led to a logical and correct diagnosis before death, Ann. Int. Med. 9: 340-349, 1935. LinkGoogle Scholar15. Mahaim I: Les tumeurs et les polypes du coeur, Etude anatomo-clinique, 1945, Masson and Cie, Paris. Google Scholar16. McCandlessFaloon FDWW: The diagnosis of metastatic tumor by cytological examination of the pericardial fluid; report of a case using Shorr's stain, Ann. Int. Med. 29: 1157-1168, 1948. LinkGoogle Scholar17. LeichtlingReibsteinSteinBass MHBMHHE: Carcinoma diagnosed by examination of pericardial fluid, New England J. Med. 247: 884-885, 1952. CrossrefMedlineGoogle Scholar18. SlaterKroopZuckerman SRIGS: Constrictive pericarditis caused by solitary metastatic carcinosis of the pericardium and complicated by radiation fibrosis of the mediastinum, Am. Heart J. 43: 401-412, 1952. CrossrefMedlineGoogle Scholar19. Yater WM: Tumors of the heart and pericardium: pathology, symptomatology and report of 9 cases, Arch. Int. Med. 48: 627-666, 1931. CrossrefGoogle Scholar20. Coulter WW: Diagnosis of primary cardiac neoplasms, Texas State J. Med. 46: 596-598, 1950. MedlineGoogle Scholar21. LübschitzLundsteenForchhammer KEE: Primary malignant heart tumor diagnosed in vivo with the aid of artificial pneumopericardium, Radiology 52: 79-87, 1949. CrossrefMedlineGoogle Scholar22. DeLoachHaynes JFJW: Secondary tumors of the heart and pericardium, Arch. Int. Med. 91: 224-249, 1953. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Washington, D. C.*Received for publication November 30, 1954.From the Departments of Medicine and Pathology, The George Washington University School of Medicine, Washington, D. C. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAn autopsy record study of neoplastic lesions of heart in sudden deathsCardiac TumorsCardiac TumorsThe management of cardiac tamponade. Drainage of pericardial effusionsHerztumoren (Tumoren von Myokard und Perikard)Tumoren des HerzensPercutaneous balloon pericardiotomy for the treatment of cardiac tamponade and large pericardial effusions: Description of technique and report of the first 50 casesSubxiphoid Pericardiotomy in the Diagnosis and Management of Large Pericardial Effusions Associated with MalignancyCase Report: Acute Presentation of Pseudo Myocardial Infarction Secondary to Metastatic CancerCase 49-1990Malignant pericardial tamponadeElectrocardiographic pseudo-myocardial infarct pattern in malignant cardiac diseaseTumoren des HerzensSuccessful management of malignant pericardial effusion in metastatic squamous cell carcinoma of the uterine cervixTumors of the heart and pericardiumThe Restrictive CardiomyopathiesMetastatic Malignant Melanoma Presenting Clinically as Obstruction of the Right Ventricular Inflow and Outflow TractsElectrocardiographic markers of cardiac metastasisCase 27-1986Severe Pericarditis as a Presenting Sign of Bronchogenic CarcinomaCardiac metastasis from uterine leiomyosarcomaRenal cell carcinoma with solitary metastases to pericardiumErgebnisse der 32P-Therapie maligner Ergüsse basierend auf dem Krankenkollektiv der Essener Tumorklinik in der Zeit von 1974–1982Diagnostic role of computed tomography in pericardial heart disease: Congenital defects, thickening, neoplasms, and effusionsClinical and Pathologic Features of Metastatic Neoplasms of the PericardiumTumoren des HerzensPericardial disease in patients with cancerPericardial Window for Malignant Pericardial EffusionMetastatic Cardiac Tumor Demonstrated by 201Thallium ScanRight ventricular obstruction secondary to intracardiac metastatic osteosarcomaCardiac disease in patients who have malignanciesCardiac Complications of MalignancyMetastatic carcinoma presenting as obstruction to the right ventricular outflow tractEffusive-constrictive hemodynamic pattern due to neoplastic involvement of the pericardiumCardiac Metastases in Lung CancerTricuspid stenosis secondary to metastatic melanomaThoracic Metastasis in Malignant MelanomaThe Management of Pericardial Effusion in Cancer PatientsTumoren des HerzensCase 35-1975Herz- und PerikardtumorenCardiac lymphatic involvement by metastatic tumorObstruction of the right ventricular outflow tract due to metastasisLipoma of the corpus callosum with atypical calcificationMetastatic disease to the heartPostradiation Pericarditis with Chronic Pericardial EffusionDAVID S. MASLAND, M.D., C. T. ROTZ JR., M.D., JOHN H. HARRIS JR., M.D.The heart in malignant melanomaPericardial Mesothelioma Presented as Constrictive Pericardial DiseaseCase 22-1965Case 7-1963Secondary Malignant Tumors of the PericardiumComplete Atrioventricular Block due to Cardiac Metastasis of Bronchogenic CarcinomaINCIDENCE OF CARDIAC ARRHYTHMIAS FOLLOWING NONCARDIAC THORACIC SURGERYMetastatic leiomyosarcoma of the heart∗Herz- und PerikardtumorenPrimary mesothelioma of the pericardiumAntemortem diagnosis of metastatic sarcoma to the heart: A case reportTumors of the Heart and Pericardium Diagnosis and Surgical TreatmentChaotic heart due to metastatic synoviomaMediastinal lymphoma simulating primary heart disease∗HODGKIN'S SARCOMA SIMULATING VENTRICULAR ANEURYSM*WILLIAM O. SMITH, CHARLES D. TOOL, JAMES F. HAMMARSTEN 1 June 1955Volume 42, Issue 6Page: 1238-1245KeywordsAutopsyClinical pathologyHeartMalignant tumorsPericardium ePublished: 1 December 2008 Issue Published: 1 June 1955 PDF downloadLoading ...