EXFOLIATIVE DERMATITIS DUE TO PHENOBARBITAL: REPORT OF A CASE WITH RECOVERY
Authors: Sherwood W. Barefoot, J. Lamar Callaway
Journal: Annals of Internal Medicine (1943)

Case Reports1 January 1943EXFOLIATIVE DERMATITIS DUE TO PHENOBARBITAL: REPORT OF A CASE WITH RECOVERYSHERWOOD W. BAREFOOT, M.D., J. LAMAR CALLAWAY, M.D.SHERWOOD W. BAREFOOT, M.D., J. LAMAR CALLAWAY, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-18-1-105 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSince their introduction for clinical use in 1913, the barbiturates have found an increasingly prominent and deserved place among the commonly used sedatives. The increasing number of reports during recent years regarding their toxic reactions is an indication of their popularity.The incidence of toxic reactions due to the barbituric acid derivatives varies considerably in different hands. Fifteen years after their introduction Menninger,1after a thorough review of the literature, was able to find only 41 instances of cutaneous eruptions attributed to barbiturates. To this list, he added three of his own cases. In 1927 Jackson2reported six instances of...Bibliography1. MENNINGER WC: Skin eruptions with phenobarbital (luminal), Jr. Am. Med. Assoc., 1928, xci, 181. Google Scholar2. JACKSON AS: Toxic reactions from phenobarbital (luminal), Jr. Am. Med. Assoc., 1927, lxxxviii, 642-643. CrossrefGoogle Scholar3. SCARLETTMACNAB EPDS: Poisoning from phenobarbital (luminal), Canad. Med. Assoc. Jr., 1935, xxxiii, 635-641. Google Scholar4. HANESYATES FMA: Analysis of four hundred instances of chronic bromide intoxication, South. Med. Jr., 1938, xxxi, 667-671. CrossrefGoogle Scholar5. HUEBER E: Ein Fall von Luminalvergiftung mit tödlichem Ausgang, München. med. Wchnschr., 1919, lxvi, 1090. Google Scholar6. HAMILTONGEIGERROTH ESCWJH: Luminal poisoning with conjunctival residue, Illinois Med. Jr., 1926, xlix, 344-346. Google Scholar7. CHAVANYVANNIER JAPE: Toxidermie barbituaigue à type d'erythème scarlatiniforme infiltré, Progrès méd., 1929, xliv, 1685-1693. Google Scholar8. POOLE AK: Drug reactions from barbital and phenobarbital, Yale Jr. Biol. and Med., 1929, i, 345-351. Google Scholar9. LANCASTER AH: Luminal dermatitis with case reports, South. Med. Jr., 1932, xxv, 1142-1145. CrossrefGoogle Scholar10. MILLARD RJ: Three cases of 'luminal' poisoning, Med. Jr. Australia, 1933, ii, 518-519. CrossrefGoogle Scholar11. HAUBRICK BP: Phenobarbital poisoning, New England Jr. Med., 1934, ccxi, 264-267. CrossrefGoogle Scholar12. HICKMANN M: Luminalkrankheit unter dem Bilde der Dermatitis exfoliativa mid tödlichem Ausgang, Ztschr. f. Kinderh., 1935, lvii, 358-360. CrossrefGoogle Scholar13. SWEITZERLAYMAN SECW: Severe cutaneous reactions to the barbiturates, Minnesota Med., 1937, xx, 92-96. Google Scholar14. WILEBENSON UJJA: Exfoliative dermatitis due to phenobarbital with fatal outcome; report of two cases, ANN. INT. MED., 1940, xiii, 1243-1249. Google Scholar15. SEXTONPIKENIELSON DLGMA: Exfoliative dermatitis and death due to phenobarbital, Jr. Am. Med. Assoc., 1941, cxvi, 700-701. CrossrefGoogle Scholar16. WINERBAER NJRL: Exfoliative dermatitis due to phenobarbital, Arch. Dermat. and Syph., 1941, xliii, 473-484. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: SHERWOOD W. BAREFOOT, M.D.; J. LAMAR CALLAWAY, M.D.Affiliations: Durham, North Carolina*Received for publication May 3, 1941.From the Section of Dermatology and Syphilology of the Department of Medicine, Duke University School of Medicine, Durham, North Carolina. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe Abuse of Sedative Drugs in the Practice of Medicine 1 January 1943Volume 18, Issue 1Page: 105-110KeywordsDermatologySedatives ePublished: 1 December 2008 Issue Published: 1 January 1943 PDF downloadLoading ...