Cine-aortographic Evaluation of Aortic Insufficiency
Authors: JOHN S. BARRETT
Journal: Annals of Internal Medicine (1964)

Article1 December 1964Cine-aortographic Evaluation of Aortic InsufficiencyUnsuspected Idiopathic Aneurysmal Dilatation of the Aortic Root as a Possible Indication of the Marfan SyndromeJOHN S. BARRETT, M.D., JOHN HELWIG JR., M.D., F.A.C.P., CALVIN F. KAY, M.D., F.A.C.P., JULIAN JOHNSON, M.D., F.A.C.S.JOHN S. BARRETT, M.D., JOHN HELWIG JR., M.D., F.A.C.P., CALVIN F. KAY, M.D., F.A.C.P., JULIAN JOHNSON, M.D., F.A.C.S.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-61-6-1071 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSince 1961, percutaneous retrograde femoral cine-aortography has been utilized at the Hospital of the University of Pennsylvania in the evaluation of patients prior to cardiac surgery, especially surgery for disease of the aortic valve. Cine-aortography, done in conjunction with the determination of pressure gradients across the aortic valve, allows one to make an anatomic evaluation of the aortic root and aortic valve and also provides an evaluation of the status of the coronary arteries.From November 1, 1961, to December 31, 1963, 211 patients have undergone retrograde cine-aortography without mortality or serious morbidity. Among these was Patient D. K., a...References1. STEINBERGGELLER IW: Aneurysmal dilatation of aortic sinuses in arachnodactyly. Diagnosis during life in three cases. Ann. Intern. Med. 43: 120, 1955. LinkGoogle Scholar2. STEINBERGMANGIARDINOBLE IJLWJ: Aneurysmal dilatation of the aortic sinuses in Marfan's syndrome: (angiocardiographic and cardiac catheterization studies in identical twins). Circulation 16: 368, 1957. CrossrefMedlineGoogle Scholar3. STEINBERG I: Dilatation of the aortic sinuses in the Marfan syndrome: roentgen findings in five new cases. Amer. J. Roentgen. 83: 302, 1960. Google Scholar4. LEVINEHARVEY SAWP: Clinical Auscultation of the Heart, 2nd ed. W. B. Saunders Co., Philadelphia, 1959, p. 312. Google Scholar5. SEGALTABESHIMBRIGLIALIKOFF BLEJFW: The Marfan's syndrome: (necropsy findings in three patients with a review of the cardiovascular complications). Angiology 13: 444, 1962. CrossrefGoogle Scholar6. BOWERS D: The electrocardiogram in Marfan's syndrome. Amer. J. Cardiol. 7: 661, 1961. CrossrefGoogle Scholar7. BOWERS D: An electrocardiographic pattern associated with mitral valve deformity on Marfan's syndrome. Circulation 23: 30, 1961. CrossrefGoogle Scholar8. MCKUSICK VA: Heritable Disorders of Connective Tissue, 2nd ed. C. V. Mosby Co., St. Louis, 1960, p. 87. Google Scholar9. ERDHEIM J: Medionecrosis aortae idiopathica cystica. Virchow Arch. Path. Anat. 273: 454, 1929, 276: 187, 1930. CrossrefGoogle Scholar10. WAGENVOORTNEUFELDEDWARDS CAHNJE: Cardiovascular system in Marfan's syndrome and in idiopathic dilatation of the ascending aorta. Amer. J. Cardiol. 9: 496, 1962. CrossrefMedlineGoogle Scholar11. EDWARDS JE: An Atlas of Acquired Diseases of the Heart and Great Vessels, Vol. I. W. B. Saunders Co., Philadelphia, 1961, p. 153. Google Scholar12. MCKUSICKLOGUEBAHNSON VARBHT: Association of aortic valvular disease and cystic medial necrosis of the ascending aorta. Circulation 16: 188, 1957. CrossrefMedlineGoogle Scholar13. COEHELOPIMENTEL EJC: Diffuse endomyocardial fibrosis. Amer. J. Med. 35: 569, 1963. CrossrefMedlineGoogle Scholar14. GORESEIWERT IVJ: Dissecting aneurysm of the aorta. Arch. Path. 53: 121, 1952. Google Scholar15. SCHNITKERBAYER MACA: Dissecting aneurysm in young individuals, particularly in association with pregnancy, with report of a case. Ann. Intern. Med. 20: 486, 1944. LinkGoogle Scholar16. WEAVEREDWARDSBRANDENBURG WFJERO: Idiopathic dilatation of the aorta with aortic valvular insufficiency: a possible forme fruste of Marfan's syndrome. Proc. Mayo Clin. 34: 518, 1959. MedlineGoogle Scholar17. BACCHUS H: A quantitative abnormality in serum mucoproteins in the Marfan's syndrome. Amer. J. Med. 25: 744, 1958. CrossrefMedlineGoogle Scholar18. BACCHUS H: Serum seromucoid and acid mucopolysaccharide in the Marfan's syndrome. J. Lab. Clin. Med. 55: 221, 1960. MedlineGoogle Scholar19. LEEMINGMCKUSICK JTVA: Serum seromucoid levels in the Marfan syndrome. Bull. Hopkins Hosp. 110: 38, 1962. MedlineGoogle Scholar20. SJOERDSMADAVIDSONUDENFRIENDMITOMA AJDSC: Increased excretion of hydroxyproline in Marfan's syndrome. Lancet II: 994, 1958. CrossrefGoogle Scholar21. MARKSGERSON JKL: Importance of autopsies—an illustrative case. JAMA 168: 1450, 1958. CrossrefMedlineGoogle Scholar22. MCKUSICK VA: Heritable Disorders of Connective Tissue, 2nd ed., C. V. Mosby Co., St. Louis, 1960, p. 107. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Philadelphia, PennsylvaniaFrom the Cardiovascular Clinical Research Center, Hospital of the University of Pennsylvania and the Departments of Medicine and Surgery, University of Pennsylvania School of Medicine, Philadelphia, Pa.This study was supported in part by the John A. Hartford Foundation and by grants HE-06352 and HE-5239 from the U. S. Public Health Service, Bethesda, Md.Dr. Barrett is a fellow of the Heart Association of Southeastern Pennsylvania.Requests for reprints should be addressed to John S. Barrett, M.D., Hospital of the University of Pennsylvania, 3400 Spruce St., Philadelphia, Pa. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByDoes dilatation of the sinotubular junction cause aortic regurgitation?Aortic Root Dilatation as a Cause of Isolated, Severe Aortic Regurgitation Prevalence, Clinical and Echocardiographic Patterns, and Relation to Left Ventricular Hypertrophy and FunctionMARY J. ROMAN, M.D., RICHARD B. DEVEREUX, M.D., NATHANIEL W. NILES, M.D., CLARE HOCHREITER, M.D., PAUL KLIGFIELD, M.D., NINA SATO, B.S., MARIANE C. SPITZER, JEFFREY S. BORER, M.D.Surgical Repair of Dissection of the Upper Descending Thoracic Aorta and Discrete Ascending Aortic AneurysmErworbene HerzklappenfehlerKardiovascul�re Manifestationsformen des Marfan SyndromsREFERENCESReplacement of the mitral valve, aortic valve, and ascending aorta with coronary transplantation in a child with the Marfan syndromeAortic root aneurysm—Radiographic and pathologic featuresRepair of ascending aortic aneurysm and aortic regurgitation complicated by acute cardiac compression by pectus excavatum in Marfan's syndromePrimary abnormalities of the mitral valve in Marfan's syndrome. Electrocardiographic findings.Idiopathic Cystic Medionecrosis and Aneurysmal Dilatation of the Ascending AortaMedical Aspects of Open-Heart SurgeryHistopathology of Striae Distensae, with Special Reference to Striae and Wound Healing in the Marfan Syndrome*Family studies of the Marfan syndromeSymptomatic Valvular Myxomatous Transformation (The Floppy Valve Syndrome)Annulo-aortic ectasia with cystic medial necrosisBiographische Aspekte der entzündlichen Klappeninsuffizienz 1 December 1964Volume 61, Issue 6Page: 1071-1083KeywordsAortaAortic valveCardiac surgeryCardiology and cardiovascular diseasesHospital medicineLongitudinal studiesMedical servicesMorbidityMortalityThoracic surgery Issue Published: 1 December 1964 PDF DownloadLoading ...