Immune Thrombocytopenia Gammaglobulin, and Seropositivity to the Human T-Lymphotropic Virus Type III
Authors: YVES LAURIAN
Journal: Annals of Internal Medicine (1986)

Letters and Corrections1 July 1986Immune Thrombocytopenia Gammaglobulin, and Seropositivity to the Human T-Lymphotropic Virus Type IIIYVES LAURIAN, M.D., PHILIPPE LE BRAS, M.D., AXEL ELLRODT, M.D., PATRICK ALVIN, M.D.YVES LAURIAN, M.D.Search for more papers by this author, PHILIPPE LE BRAS, M.D.Search for more papers by this author, AXEL ELLRODT, M.D.Search for more papers by this author, PATRICK ALVIN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-105-1-145_3 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editior: Walsh and colleagues (1) and Abrams and colleagues (2) recently described the successful treatment of immune thrombocytopenia with steroids or splenectomy in patients with antibodies to the lymphadenopathy-associated virus/human T-lymphotropic virus type III (LAV/HTLV III). We report our experience with intravenous gammaglobulin in such patients.Immune thrombocytopenia occurred in 17 patients (12 hemophiliacs, 4 intravenous drug users, 1 homosexual man) out of 248 LAV/HTLV-III-seropositive patients seen in our hospital since 1981. The presence of these antibodies was assessed by an enzyme-linked immunosorbent assay (ELA-VIA; Diagnostics Pasteur, France) and was confirmed by Western blot analysis. Thrombocytopenia was severe...References1. WALSH C, KRIGEL R, LENETTE E, and KARPATKIN S. Thrombocytopenia in homosexual patients: prognosis, response to therapy, and prevalence of antibody to the retrovirus associated with the acquired immunodeficiency syndrome. Ann Intern Med. 1985;103:542-5. LinkGoogle Scholar2. ABRAMS D, KIRPOV D, and GOEDERT J. Antibodies to human T-lymphotropic virus type III and development of acquired immunodeficiency syndrome in homosexual man presenting with immune thrombocytopenia. Ann Intern Med. 1986;104:47-50. LinkGoogle Scholar3. MINTZER D, REAL F, JOVINO L, and KROWN S. Treatment of Kaposi's sarcoma and thrombocytopenia with vincristine in patients with the acquired immunodeficiency syndrome. Ann Intern Med. 1985;102:200-2. LinkGoogle Scholar4. DELFRAISSY J, TERTIAN G, DREYFUS M, and TCHERNIA G. Intravenous gammaglobulin, thrombocytopenia, and the acquired immunodeficiency syndrome [Letter]. Ann In tern Med. 1985;103:478. AbstractGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: YVES LAURIAN, M.D.; PHILIPPE LE BRAS, M.D.; AXEL ELLRODT, M.D.; PATRICK ALVIN, M.D.Affiliations: Hôpital Universitaire de Bicêtre 94275 Le Kremilin Bicêtre Cedex France PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byUtilisation thérapeutique des immunoglobulines polyvalentes en hématologieUtilisation thérapeutique des immunoglobulines polyvalentes en hématologieUsefulness of a low‐dose intravenous immunoglobulin regimen for the treatment of thrombocytopenia associated with AIDSIntravenous immunoglobulin in the treatment of human immunodeficiency virus-related thrombocytopeniaSpontaneous subarachnoid hemorrhage in an HIV patientUse of Intravenous Gammaglobulin as an Immune Replacement and an Immune SuppressantIsolated thrombocytopenia in patients infected with HIV: Treatment with intravenous gammaglobulinTherapie mit ImmunglobulinenMANAGEMENT OF HUMAN IMMUNODEFICIENCY VIRUS-INDUCED THROMBOCYTOPENIA IN HEMOPHILIALong-Term Evaluation of HIV Antigen and Antibodies to p24 and gp41 in Patients with HemophiliaIntravenous Immunoglobulin Therapy of Idiopathic Thrombocytopenic Purpura in Childhood and Adolescence 1 July 1986Volume 105, Issue 1Page: 145-146KeywordsAntibodiesDiagnostic techniquesEnzyme linked immunosorbent assayHIVHomosexualsIdiopathic thrombocytopenic purpuraImmunohistochemistrySplenectomySteroidsWestern blot ePublished: 1 December 2008 Issue Published: 1 July 1986 PDF downloadLoading ...