INTRA-ARTICULAR HYDROCORTISONE IN THE TREATMENT OF ARTHRITIS
Authors: J L HOLLANDER
Journal: Annals of Internal Medicine (1953)

Article1 October 1953INTRA-ARTICULAR HYDROCORTISONE IN THE TREATMENT OF ARTHRITISJOSEPH L. HOLLANDER, M.D., F.A.C.P.JOSEPH L. HOLLANDER, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-39-4-735 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptFor many years physicians have attempted to suppress arthritic inflammation by injecting petrolatum, iodized oil, lactic acid, procaine or antibiotics directly into the affected synovial space.1Dr. George Thorn2was the first to inject compound F of Kendall (now called hydrocortisone) into an arthritic knee joint. However, as luck would have it, not only did the treated joint improve but the general condition of his patient also improved the next day. This made him assume that the particular patient was extremely sensitive to the systemic action of the hormone, and the profound local anti-inflammatory effect of small doses of hydrocortisone...Bibliography1. Hollander JL: Comroe's Arthritis and allied conditions, 5th Ed., 1953, Lea and Febiger, Philadelphia, pp. 319-336. Google Scholar2. Thorn GW: Personal communication. Google Scholar3. HorvathHollander SMJL: Intra-articular temperature as a measure of joint reaction, J. Clin. Investigation 28: 543, 1949. CrossrefGoogle Scholar4. HollanderBrownJessarBrown JLEMRACY: Hydrocortisone and cortisone injected into arthritic joints, J. A. M. A. 147: 1629, 1951. CrossrefMedlineGoogle Scholar5. StevensonZucknerFreyberg CRJRH: Intra-articular hydrocortisone (compound F) acetate, Ann. Rheumat. Dis. 11: 112, 1952. CrossrefMedlineGoogle Scholar6. DuffRopesJessarSteinbergDavisonRawls IFMWRACLRWB: Discussion at meeting of American Rheumatism Association, Ann. Rheumat. Dis. 11: 302, 1952. Google Scholar7. Kashtan HA: Hydrocortisone (compound F) in arthritic joints, Harper Hosp. Bull. 10: 143, 1952. MedlineGoogle Scholar8. De SezeRobinChevallierFrancon SJJJ: Initial results with intra-articular hydrocortisone in rheumatology, Presse méd. 60: 1465, 1952. Google Scholar9. ZaccoDohanHollander MFCJL: Disposition of intra-articular hydrocortisone in articular tissues. In preparation. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Philadelphia, Pennsylvania*Presented at the Thirty-Fourth Annual Session of the American College of Physicians, Atlantic City, New Jersey, April 17, 1953.From the Arthritis Section, Department of Medicine, Hospital of the University of Pennsylvania.Supported by grants from the Helon Augusta Parkhill Foundation, from Merck and Co., Inc., and from the National Institute of Arthritis and Metabolic Diseases, United States Public Health Service. 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SMYTH, M.D., F.A.C.P.Absorption of Hydrocortisone from the Joint Cavity into the CirculationSome Observations on the Therapeutic Significance of Hydrocortisone Injections in Rheumatoid ArthritisTherapeutic Trials in Acute Gouty ArthritisHYDROCORTISONE IN PAINFUL SHOULDER A CONTROLLED TRIALDiscussion on HydrocortisoneTHE USE OF INTRA-ARTICULAR HYDROCORTISONE, ITS ANALOGS, AND ITS HIGHER ESTERS IN ARTHRITISIntra-articular Hydrocortisone in Rheumatoid Arthritis: Clinical and Laboratory StudiesHYDROCORTISONE IN LESIONS OF SOFT TISSUERheumatoid arthritis: A review of recent advances in our knowledge concerning pathology, diagnosis, and treatmentLocal Anti-Rheumatic Effectiveness of Higher Esters and Analogues of HydrocortisoneThe Treatment of OsteoarthritisRHEUMATISM THE AMERICAN SCENETENNIS-ELBOW TREATED WITH HYDROCORTISONE ACETATEThe Mother as NurseLocal Administration of Hydrocortisone 1 October 1953Volume 39, Issue 4Page: 735-746KeywordsAntibioticsArthritisHormonesHospital medicineInflammationKnee jointsLactic acidMedical servicesMetabolic disordersOils ePublished: 1 December 2008 Issue Published: 1 October 1953 PDF downloadLoading ...