THE TREATMENT OF AMEBIASIS, WITH A PRELIMINARY REPORT ON THE USE OF AUREOMYCIN
Authors: C F GUTCH
Journal: Annals of Internal Medicine (1950)

Article1 December 1950THE TREATMENT OF AMEBIASIS, WITH A PRELIMINARY REPORT ON THE USE OF AUREOMYCINC. F. GUTCH, M.D.C. F. GUTCH, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-33-6-1407 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAdequate therapy of amebiasis—the human infection by Endamoeba histolytica—demands treatment of possible systemic as well as intestinal infection.1, 2 Since the use of ipecac early in the Nineteenth Century, the search for more effective drugs has continued; however, despite introduction of improved therapeutic agents, a significant failure rate and also a definite incidence of toxicity have not been eliminated.Drugs which have been used against amebiasis include:1. Emetine group—ipecac, emetine, and emetine bismuth iodide.2. Oxyquinoline derivatives—Chiniofon, Vioform, Diodoquin, Chloroquine, Win 246 and Win 1011.3.Organic arsenicals(pentavalent arsenicals)—carbarsone, Treparsol, Acetarsone. (The trivalent analogues of carbarsone with substituted...Bibliography1. AlbrightGordon ECES: Present status of the problem of amebiasis, Arch. Int. Med. 79: 253-271 (March) 1947. CrossrefGoogle Scholar2. CappsBennett RBA: The incidence of liver involvement in chronic amebiasis, J. Clin. Investigation 28: 773 (July) 1949. Google Scholar3. AndersonJohnstoneBostickChevarriaPacker HHHGWAPH: Thioarsenates in amebiasis, J. A. M. A. 140: 1251-1256 (Aug. 20) 1949. CrossrefMedlineGoogle Scholar4. Most H: Recent advances in the therapy of the more common protozoan and helminthic infections of man, Bull. New York Acad. Med. 25: 717 (Nov.) 1949. MedlineGoogle Scholar5. McVayLairdSprunt LVRLDH: A preliminary report of the successful treatment of amebiasis with aureomycin, Science 109: 590-591 (June 10) 1949. CrossrefMedlineGoogle Scholar6. DennisBerberianHansen EWDASS: Amoebacidal activity of bismuthoxy p-N-glycolyl-arsenilate and 7-iodo-4 (1-methyl-4-diethylamino-butylamino) quinoline diphosphate, Am. J. Trop. Med. 29: 683-689 (Sept.) 1949. CrossrefMedlineGoogle Scholar7. FullerFaust FWEC: Aureomycin in the cultivation of Endamoeba histolytica , Science 110: 509-510 (Nov. 11) 1949. CrossrefMedlineGoogle Scholar8. BrainardLennetteMeiklejohnBruynClark HEHGHBWH: Clinical evaluation of aureomycin, J. Clin. Investigation 28: 983-986 (Sept.) 1949. Google Scholar9. HarrellMeansLawsonLide GTMRBTN: Observations on tuberculous meningitis treated with oral aureomycin, Ibid, 1050. Google Scholar10. HarrellHeilman WEFR: Aureomycin: studies on absorption, diffusion, and excretion, Proc. Staff Meet., Mayo Clin. 24: 157 (March 30) 1949. MedlineGoogle Scholar11. HarveyMirickSchaub JCGSIS: Clinical experiences with aureomycin, J. Clin. Investigation 28: 987-991 (Sept.) 1949. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Lincoln, Nebraska*Presented before the Nebraska Regional Meeting of the American College of Physicians, Lincoln, Nebraska, February 11, 1950. Received for publication March 4, 1950.From the Department of Internal Medicine, U. S. Veterans Administration Hospital, Lincoln, Nebraska.Reviewed in the Veterans Administration and published with the approval of the Chief Medical Director. The statements and conclusions published by the author are the result of his own study and do not necessarily reflect the opinion or policy of the Veterans Administration. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 December 1950Volume 33, Issue 6Page: 1407-1412KeywordsAdverse reactionsAmebiasisBismuthChloroquineDrug therapyDrugsHospital medicineToxicity ePublished: 1 December 2008 Issue Published: 1 December 1950 PDF downloadLoading ...