FAILURE OF SALT RESTRICTION TO MODIFY BLOOD PRESSURE IN THE ACCELERATED PHASE OF PRIMARY HYPERTENSION
Authors: G A PERERA
Journal: Annals of Internal Medicine (1955)

Article1 December 1955FAILURE OF SALT RESTRICTION TO MODIFY BLOOD PRESSURE IN THE ACCELERATED PHASE OF PRIMARY HYPERTENSIONGEORGE A. PERERA, M.D.GEORGE A. PERERA, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-43-6-1195 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSalt restriction in the treatment of hypertension was first advocated more than a half-century ago.1 The subsequent history of this therapeutic measure has been reviewed,2, 3 and it has also been reported that hypertensive patients with secondary renal damage or with primary renal disease may be benefited.4The present study was undertaken to study further the effects of sodium chloride restriction in patients with primary hypertension who had advanced arteriolar nephrosclerosis.CASE MATERIAL AND METHODSFour men and two women with documented primary hypertension, clinically in the accelerated ("malignant") phase, were studied on the wards of the Presbyterian Hospital. All...Bibliography1. AmbardBeaujard LE: Causes de l'hypertension artérielle, Arch. gén. de méd. 1: 520, 1904. Google Scholar2. PinesPerera KLGA: Sodium chloride restriction in hypertensive vascular disease, M. Clin. North America 33: 713 (May) 1949. CrossrefMedlineGoogle Scholar3. ChapmanGibbons CBTD: The diet and hypertension: a review, Medicine 29: 29, 1950. CrossrefMedlineGoogle Scholar4. Kempner W: Treatment of kidney disease and hypertensive vascular disease with rice diet, North Carolina M. J. 6: 1, 1945. Google Scholar5. PereraBlood GADW: The relationship of sodium chloride to hypertension, J. Clin. Investigation 26: 1109, 1947. CrossrefMedlineGoogle Scholar6. PetersWakemanEisenmanLee JPAMAJC: Total acid-base equilibrium of plasma in health and disease, J. Clin. Investigation 6: 517, 1929. CrossrefMedlineGoogle Scholar7. GrollmanHarrison ATR: Effect of rigid sodium restriction on blood pressure and survival of hypertensive rats, Proc. Soc. Exper. Biol. and Med. 60: 52, 1945. CrossrefMedlineGoogle Scholar8. Viersma HJ: De behandeling van hypertensie met zoutloos diett, Nederl. tijdschr. v. geneesk. 91: 2042, 1947. Google Scholar9. Schroeder HA: Low salt diets and arterial hypertension, Am. J. Med. 4: 578, 1948. CrossrefMedlineGoogle Scholar10. Perera GA: The adrenal cortex and hypertension, Bull. New York Acad. Med. 26: 75, 1950. MedlineGoogle Scholar11. KnowltonLoebSeegalStoerkBerg AIENBCHCJL: Development of hypertension in the adrenalectomized nephritic rat maintained on NaCl, Proc. Soc. Exper. Biol. and Med. 74: 661, 1950. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Received for publication May 21, 1955.From the Department of Medicine, Columbia University College of Physicians and Surgeons, and the Presbyterian Hospital, New York, N. Y.†This study was supported by grants from the National Heart Institute (U.S.P.H.S.), the Albert and Mary Lasker Foundation, the Albert H. and Jessie D. Wiggin Foundation, and the Irwin Strasburger Memorial Medical Foundation. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byExaggerated Natriuresis in Salt-Sensitive Essential HypertensionDietary Sodium and Essential Hypertension: Some Myths, Hopes, and TruthsJOHN H. LARAGH, M.D., MARK S. PECKER, M.D.Vasoconstriction-volume analysis for understanding and treating hypertension: The use of renin and aldosterone profilesDiuretics and Diet in Hypertension 1 December 1955Volume 43, Issue 6Page: 1195-1198KeywordsHospital medicineHypertensionLesionsLongitudinal studiesPatient advocacyPrimary hypertensionRenal diseasesSaltsSodium chlorideSurgeons ePublished: 1 December 2008 Issue Published: 1 December 1955 PDF downloadLoading ...