FURTHER STUDIES ON THE THYMUS AND PINEAL GLANDS
Authors: L. G. Rowntree, J. H. Clark, A. Steinberg, A. M. Hanson, N. H. Einhorn, W. A. Shannon
Journal: Annals of Internal Medicine (1935)

Article1 October 1935FURTHER STUDIES ON THE THYMUS AND PINEAL GLANDSL. G. ROWNTREE, M.D., F.A.C.P., J. H. CLARK, M.D., F.A.C.P., A. STEINBERG, B.S., A. M. HANSON, M.D., N. H. EINHORN, M.D., W. A. SHANNON, M.D.L. G. ROWNTREE, M.D., F.A.C.P.Search for more papers by this author, J. H. CLARK, M.D., F.A.C.P.Search for more papers by this author, A. STEINBERG, B.S.Search for more papers by this author, A. M. HANSON, M.D.Search for more papers by this author, N. H. EINHORN, M.D.Search for more papers by this author, W. A. SHANNON, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-9-4-359 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe results of our early studies on the biological effects of thymus extract were published in July 1934. In the present communication we wish to present further studies on the thymus gland, up to April 8, 1935, and also the biological effects of pineal extract (Hanson) when administered to succeeding generations with the identical procedure followed in our thymus studies.FURTHER STUDIES OF THE THYMUS GLANDOur knowledge of the physiology of the thymus dates from Friedleben in 1858 who found that it was not indispensable to life and was concerned in some way with blood formation, with nutrition and...References1. ROWNTREECLARKHANSON LGJHAM: The biological effects of thymus extract (Hanson), Jr. Am. Med. Assoc., 1934, ciii, 1425-1430. CrossrefGoogle Scholar2. ADDISONHOWE WHJW: Congenital hypertrophy of the eye in an albino rat, Anat. Rec., 1926, xxxii, 271. CrossrefGoogle Scholar3. BASCH K: Über Ausschaltung der Thymusdrüse, Verhandl. d. Gesellsch. deutsch. Naturf. u. Aerzte, 1902, Leipsiz. Also: Wien. klin. Wchnschr., 1903, xvi, 893-896. Google Scholar4. 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HEWER EE: The structure of the thymus gland and of the reproductive organs in white rats together with some observations on the breeding capacity of these animals, Jr. Physiol., 1914, l, 434. Google Scholar11. KLOSEVOGT HH: Klinik und Biologie der Thymusdrüse mit besonderer Berücksichtigung ihrer Beziehungen zu Knochen- und Nervensystem, Beitr. z. klin. Chir., 1910, lxix, 1-200. Google Scholar12. KLOSE H: Über Thymusexstirpation und ihre Folgen, Arch. f. klin. Chir., 1910, xcii, 1125-1141. Google Scholar13. NITSCHKE A: Darstellung zweier wirksamer und spezifischer Thymussubstanzen, ihr Einfluss auf Kalk und Phosphatgehalt des Kaninchenserums, Ztschr. f. d. ges. exper. Med., 1929, lxv, 637-650. CrossrefGoogle Scholar14. NITSCHKE A: Die Beeinflussung des Grundumsatzes durch Thymus und Milzextrakt (P Substanz), Monatschr. f. Kinderh., 1930, xlvii, 530-533. Google Scholar15. NOWINSKI VW: Forgesetzte Untersuchungen über den Einfluss des Thymocrescins auf das Wachstum, Biochem. Ztschr., 1932, ccxlix, 421-423. Google Scholar16. PARKMCCLURE EARD: Results of thymus extirpation in dog, Am. Jr. Dis. Child., 1919, xviii, 317. Google Scholar17. RIDDLEKRIZENECKY OJ: Extirpation of thymus and bursa in pigeons with a consideration of failure of thymectomy to reveal thymus function, Am. Jr. Physiol., 1931, xcvii, 343-352. CrossrefGoogle Scholar18. RIDDLEFREY OP: Growth and age involution of thymus in male and female pigeons, Am. Jr. Physiol., 1925, lxxi, 413-429. CrossrefGoogle Scholar19. UHLENHUTH ; quoted by HOSKINS: The tides of life, 1933, W. W. Norton & Co., New York. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Philadelphia, Pennsylvania*Read at the Philadelphia meeting of the American College of Physicians, April 30, 1935.From the Philadelphia Institute for Medical Research, from the Samuel Bell, Jr., Laboratory in the Philadelphia General Hospital, the Laboratories of the Philadelphia General Hospital, Philadelphia, Pennsylvania, and the Hanson Research Laboratory, Faribault, Minnesota.This work was supported by a grant from the Penrose Fund of the American Philosophical Society.We wish, also, to acknowledge with gratitude the financial assistance given one of us, Dr. Hanson, by the Josiah Macy, Jr., Foundation. 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