Zidovudine-Induced Macular Edema
Authors: Richard G. Lalonde, Jean G. Deschênes, Christopher Seamone
Journal: Annals of Internal Medicine (1991)

Brief Reports15 February 1991Zidovudine-Induced Macular EdemaRichard G. Lalonde, MD, Jean G. Deschênes, MD, Christopher Seamone, MDRichard G. Lalonde, MD, Jean G. Deschênes, MD, Christopher Seamone, MDAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-114-4-297 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptZidovudine has become the standard therapy for patients with altered immunity due to infection with human immunodeficiency virus (HIV). Initially, the drug was studied in patients who were in the advanced stages of HIV infection (1, 2). In that setting, it caused considerable but acceptable toxicity (1,2). More recently, zidovudine was shown to be effective in treating asymptomatic HIV-infected patients with low helper T-cell levels (3). As experience with the drug has grown, knowledge of the range of side effects has increased (1). We report the case of a patient with HIV infection and chronic anterior uveitis who had two...References1. Fischl M. State of antiretroviral therapy with zidovudine. AIDS 1989;3:S137-43. CrossrefMedlineGoogle Scholar2. FischlRichmanGrieco MDM. The efficacy of azidothymidine(AZT) in the treatment of patients with AIDS and AIDS-related complex: a double-blind, placebo-controlled trial. N Engl J Med. 1987;317:185-91. CrossrefMedlineGoogle Scholar3. VolberdingLagakosKoch PSM. Zidovudine in asymptomatic human immunodeficiency virus infection. N Engl J Med. 1990;322:941-9. CrossrefMedlineGoogle Scholar4. HollandKreiger GA. Neurophthalmology of acquired immunodeficiency syndrome. In: Rosenblum ML, Levy RM, Bredesen DE. AIDS and the Nervous System. New York: Raven Press; 1988:103-20. Google Scholar5. PomerantzKuritzkesDe La Monte RDS. Infection of the retina by human immunodeficiency virus type I. N Engl J Med. 1987;317:1643-7. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: From Royal Victoria Hospital and McGill University, Montreal, Quebec. For current author addresses, see end of text. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDrugs Used in the Management of Human Immunodeficiency Virus/Acquired Immunodeficiency SyndromeEfavirenz-Associated Retinal Toxicity Presenting with Night Vision Defects in Patients with Human Immunodeficiency VirusA Retrospective Review of Serious Adverse Drug Reaction Reports in the Nigerian VigiFlow Database from September 2004 to December 2016RITONAVIR-ASSOCIATED TOXICITY MIMICKING RETINITIS PIGMENTOSA IN AN HIV-INFECTED PATIENT ON HIGHLY ACTIVE ANTIRETROVIRAL THERAPYDrug-induced ocular side effectsDrug-Induced Macular EdemaA woman with didanosine retinopathy and non-cirrhotic portal hypertensionDrug-induced ocular side effectsAcetylsalicylic Acid 50-78-2Decreased visual acuity in patients with cytomegalovirus retinitis and AIDSMorphologie der Augenveränderungen bei medikamentöser TherapieBilateral cystoid macular edema in a 21-year-old womanMedical and Virological Aspects of Ocular Human Immunodeficiency Virus Infection for the OphthalmologistZidovudine: Five Years LaterGavin X. McLeod, MD, Scott M. Hammer, MDSystemic antiviral drugs used in ophthalmologyAntiretroviral therapy: reverse transcriptase inhibitionMiscellaneous antibacterial and antiviral drugsMacular Edema from Zidovudine?Mitchell B. Strominger, MD, Ronald Sachs, MD, Harry M. Engel, MD 15 February 1991Volume 114, Issue 4Page: 297-298KeywordsAdverse reactionsDrugsEdemaHIVHIV infectionsHospitalsImmunityInfectious diseasesToxicityUveitis Issue Published: 15 February 1991 PDF downloadLoading ...