MYOCARDIAL LESIONS IN SUBACUTE BACTERIAL ENDOCARDITIS
Authors: E L PERRY, R G FLEMING, J E EDWARDS
Journal: Annals of Internal Medicine (1952)

Article1 January 1952MYOCARDIAL LESIONS IN SUBACUTE BACTERIAL ENDOCARDITISEDWARD L. PERRY, M.D., RALPH G. FLEMING, M.D., F.A.C.P., JESSE E. EDWARDS, M.D.EDWARD L. PERRY, M.D., RALPH G. FLEMING, M.D., F.A.C.P., JESSE E. EDWARDS, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-36-1-126 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptRecently Saphir, Katz and Gore1 stressed that the myocardial lesions in subacute bacterial endocarditis may be of more than academic interest. With the possibility of eliminating the infecting organisms by the use of the antibiotics, the myocardium comes into focus as a potential source of cardiac failure in the patient who responds satisfactorily from the point of view of infection.The primary purposes of the study here reported were to determine the nature and frequency of myocardial lesions in cases in which the patients had died of subacute bacterial endocarditis, and to ascertain the effect of penicillin therapy upon the...Bibliography1. SaphirKatzGore OLNI: The myocardium in subacute bacterial endocarditis, Circulation 1: 1155-1167, 1950. CrossrefMedlineGoogle Scholar2. Libman E: Characterization of various forms of endocarditis, J. A. M. A. 80: 813-818, 1923. CrossrefGoogle Scholar3. RothschildSacksLibman MABE: The disturbances of the cardiac mechanism in subacute bacterial endocarditis and rheumatic fever, Am. Heart J. 2: 356-374, 1927. CrossrefGoogle Scholar4. GrossFried LBM: The rôle played by rheumatic fever in implantation of bacterial endocarditis, Am. J. Path. 13: 769-798, 1937. MedlineGoogle Scholar5. Boyd W: Text-book of pathology; an introduction to medicine, 5th Ed., 1947, Lea & Febiger, Philadelphia. Google Scholar6. Bell ET: Text-book of pathology, 5th Ed., 1944, Lea & Febiger, Philadelphia. Google Scholar7. Coombs CF: Streptococcal infections of the heart, Quart. J. Med. 15: 114-130, 1922. CrossrefGoogle Scholar8. ClawsonBell BJET: A comparison of acute rheumatic and subacute bacterial endocarditis, Arch. Int. Med. 37: 66-81, 1926. CrossrefGoogle Scholar9. Thayer WS: Studies on bacterial (infective) endocarditis, Johns Hopkins Hosp. Rep. 22: 1-185, 1926. Google Scholar10. Clawson BJ: The Aschoff nodule, Arch. Path. 8: 664-685, 1929. Google Scholar11. Saphir O: Myocardial lesions in subacute bacterial endocarditis, Am. J. Path. 11: 143-156, 1935. MedlineGoogle Scholar12. de Navasquez S: The incidence and pathogenesis of myocardial lesions in subacute bacterial endocarditis, J. Path. and Bact. 49: 33-38, 1939. CrossrefGoogle Scholar13. Saphir O: Myocardial granulomas in subacute bacterial endocarditis, Arch. Path. 42: 574-580, 1946. Google Scholar14. PerryBurchellEdwards ELHBJE: Cardiac Clinics CXXVII. Congenital communication between the left ventricle and the right atrium: co-existing ventricular septal defect and double tricuspid orifice, Proc. Staff Meet., Mayo Clin. 24: 198-206, 1949. MedlineGoogle Scholar15. HammanRich LAR: Two cases of subacute bacterial endocarditis, Internat. Clin. 2: 201-237, 1933. Google Scholar16. ThalhimerRothschild WMA: On the significance of the submiliary nodules of Aschoff in rheumatic fever, J. Exper. Med. 19: 417-428, 1914. CrossrefMedlineGoogle Scholar17. Clawson BJ: An analysis of two hundred and twenty cases of endocarditis; with special reference to the subacute bacterial type, Arch. Int. Med. 33: 157-184, 1924. CrossrefGoogle Scholar18. Clawson BJ: Myocarditis, Am. Heart J. 1: 1-15, 1928. CrossrefGoogle Scholar19. SaphirWile OSA: Rheumatic manifestations in subacute bacterial endocarditis in children, Am. Heart J. 9: 29-44, 1933. CrossrefGoogle Scholar20. Von GlahmPappenheimer WCAW: Relationship between rheumatic and subacute bacterial endocarditis, Arch. Int. Med. 55: 173-185, 1935. CrossrefGoogle Scholar21. BuchbinderSaphir WCO: Heart failure in subacute bacterial endocarditis, Arch. Int. Med. 64: 336-347, 1939. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication September 2, 1950.From the Mayo Foundation and the Section on Pathologic Anatomy of the Mayo Clinic.Abridgment of thesis submitted by Dr. Perry to the Faculty of the Graduate School of the University of Minnesota in partial fulfillment of the requirements for the degree of Master of Science in Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byTroponin elevation is very common in patients with infective endocarditis and is associated with a poor outcomeCapacity Management in Inpatient Wards with Off-service Placement and a Network ViewUnexpected echocardiographic findings in one vessel coronary artery diseaseCorrelation of cardiac troponin I levels with infective endocarditis & its adverse clinical outcomesThe usefulness of serum troponin levels to predict 1-year survival rates in infective endocarditisClinical Manifestations of Native Valve EndocarditisAcute Coronary Syndrome in Infective EndocarditisSíndrome coronario agudo en la endocarditis infecciosaRole of troponin I in active infective endocarditisPathologie des EndokardCase 25-1998The spectrum of diseases of small coronery arteries and their physiologic consequencesImmune reactions in infective endocarditis. II. Relevance of circulating immune complexes, serum inhibition factors, lymphocytotoxic reactions, and antibody-dependent cellular cytotoxicity against cardiac target cellsNoninvasive methods for detection of valve vegetations in infective endocarditisExperimental cryptococcal myocarditisSurgical Treatment of Acute Aortic Regurgitation in Infective EndocarditisActive infective endocarditis: A clinicopathologic analysis of 137 necrosy patientsAlterations in myocardial function during bacterial infective cardiomyopathyPathology of the Myocardium and ValvesPathoanatomic, Pathophysiologic and Clinical Correlations in EndocarditisInfective endocarditis—1973INFECTIVE ENDOCARDITISLeft-sided valvular active infective endocarditisCase 29-1971Spontaneous Porcine Endocarditis Bacteriology and Pathology*Pathology of small coronary arteriesInfective Endocarditis in the Antibiotic EraCEREBRAL EMBOLI AS A RESULT OF "MUTE" JUVENILE ENDOCARDITISShock in infectious diseasesCORONARY EMBOLISM WITH INFARCTION IN BACTERIAL ENDOCARDITISErkrankungen des EndokardCongenital Aortic StenosisCoronary embolismRight-sided bacterial endocarditis and endarteritisDie Herz- und GefäßkrankheitenTreatment of Bacterial EndocarditisDas Elektrokardiogramm bei Endocarditis lenta 1 January 1952Volume 36, Issue 1Page: 126-137KeywordsAntibioticsEndocarditisGraduate medical educationHeart failureLesionsMyocardiumPenicillin ePublished: 1 December 2008 Issue Published: 1 January 1952 PDF downloadLoading ...