LEG ACHE: A SYMPTOMATIC INDICATION OF IRREGULAR GOUT
Authors: H PEPPER, L MANN
Journal: Annals of Internal Medicine (1961)

Article1 February 1961LEG ACHE: A SYMPTOMATIC INDICATION OF IRREGULAR GOUTHERMAN PEPPER, M.D., LOUIS MANN, M.D.HERMAN PEPPER, M.D.Search for more papers by this author, LOUIS MANN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-54-2-267 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe clinical, biochemical, and histiologic manifestations of typical gout have been described extensively, and the diagnosis is usually made without difficulty. The differential diagnosis of irregular or atypical gout, however, continues to be a problem. Irregular gout has many signs and symptoms which are not characteristic of typical gout. It is insidious in onset, causes mild arthritis, usually affects women, and progresses slowly without remission. A family history of the disease is rarely elicited. Tophi are absent.1Serum uric acid levels are at the upper limits of normal or slightly higher. The diagnosis can only be made by demonstrating sodium...Bibliography1. Duncan GG: Diseases of Metabolism. 4th Ed., page 656. W. B. Saunders Co., Philadelphia, 1959. Google Scholar2. Mason RM: Some observations on the blood uric acid levels in gout. Proc. Royal Soc. Med. 44: 289-292 (April) 1951. MedlineGoogle Scholar3. TinneyPolleyHallGiffin WSHFBEHZ: Polycythemia vera and gout; report of 8 cases. Proc. Mayo Clin. 20: 49-55 (Feb.) 1945. Google Scholar4. Riddle MC: The endogenous uric acid metabolism in pernicious anemia. J. Clin. Invest. 8: 69-88 (Dec.) 1929. CrossrefMedlineGoogle Scholar5. Ficarra BJ: Hyperuricemia in gastric cancer. Surgery 19: 223-228 (Feb.) 1946. MedlineGoogle Scholar6. Warshaw LJ: Acute attack of gout precipitated by chlorothiazide-induced diuresis. J. A. M. A. 172: 802-807 (Feb. 20) 1959. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Redwood City, California*Received for publication July 21, 1960.From the Sequoia Hospital, Redwood City, California.†Supported by a grant from Merck, Sharp & Dohme, West Point, Pa.Requests for reprints should be addressed to Herman Pepper, M.D., 50 Edgewood Road, Redwood City, California. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe Varying Picture in GoutRheumatism and Arthritis Review of American and English Literature of Recent Years (Sixteenth Rheumatism Review)CHARLEY J. SMYTH, M.D., F.A.C.P., ROGER L. BLACK, M.D., CHARLES CHRISTIAN, M.D., MACK L. CLAYTON, M.D., F.A.C.S., DONALD F. HILL, M.D., F.A.C.P., JOSEPH LEE HOLLANDER, M.D., F.A.C.P., WILLIAM M. MIKKELSEN, M.D., F.A.C.P., MAX M. MONTGOMERY, M.D., F.A.C.P., CARL M. PEARSON, M.D., F.A.C.P., HUGH A. SMYTHE, M.D., F.R.C.P. (C), L. EMMERSON WARD, M.D., F.A.C.P., HOWARD J. WEINBERGER, M.D., F.A.C.P.A Non-Articular Manifestation of Gout 1 February 1961Volume 54, Issue 2Page: 267-273KeywordsArthritisGoutMyalgiaMyositisPainSigns and symptomsSodiumUric acid ePublished: 1 December 2008 Issue Published: 1 February 1961 PDF downloadLoading ...