PLEURITIS IN SYSTEMIC LUPUS ERYTHEMATOSUS: ITS IMPORTANCE AS AN EARLY MANIFESTATION IN DIAGNOSIS
Authors: W A WINSLOW, L N PLOSS, B LOITMAN
Journal: Annals of Internal Medicine (1958)

Article1 July 1958PLEURITIS IN SYSTEMIC LUPUS ERYTHEMATOSUS: ITS IMPORTANCE AS AN EARLY MANIFESTATION IN DIAGNOSISWILLIAM A. WINSLOW, M.D., LESTER N. PLOSS, M.D., BERNARD LOITMAN, M.D.WILLIAM A. WINSLOW, M.D., LESTER N. PLOSS, M.D., BERNARD LOITMAN, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-49-1-70 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptINTRODUCTIONAlthough pleuritis and pleural effusion have long been considered as cardinal signs in the clinical picture of systemic lupus erythematosus (S. L. E.‡), these have usually been regarded as late manifestations of the disease. The feeling also prevails that unexplained pleuritis is to be regarded as tuberculous or neoplastic unless proved otherwise. However, now that the early diagnosis of S. L. E. has been facilitated by the "L. E. cell preparation," it seems well to reëvaluate pleuritis as an early sign in S. L. E. Moreover, the striking improvement in prognosis with steroid treatment makes an early diagnosis much...Bibliography1. BaehrPollack GAD: Disseminated lupus erythematosus and diffuse scleroderma, J. A. M. A. 134: 1169, 1947. CrossrefMedlineGoogle Scholar2. Baggenstoss AH: Visceral lesions in disseminated lupus erythematosus, Proc. Staff Meet. Mayo Clin. 27: 412, 1952. MedlineGoogle Scholar3. Barnwell JB (a) : Diseases of the pleura, in Cecil, R. L., and Loeb, R. F.: Textbook of medicine, 1955, W. B. Saunders Company, Philadelphia, p. 1054. (b) Baehr, G.: Disseminated lupus erythematosus, in Cecil, R. L., and Loeb, R. F.: Textbook of medicine, 1955, W. B. Saunders Company, Philadelphia, p. 495, ff. Google Scholar4. Davidson M: Practical manual of diseases of the chest, 1954, Oxford University Press, New York. Google Scholar5. DavidsonFoxGold AGLJJ: Appearance of miliary tuberculosis following therapy with ACTH and cortisone in a case of acute disseminated lupus erythematosus, Ann. Int. Med. 38: 852, 1953. LinkGoogle Scholar6. DoubGoodrichGish HPBCJR: Pulmonary aspects of polyarteritis nodosa, Am. J. Roentgenol. 71: 785, 1954. Google Scholar7. DuboisMartel ELS: Discoid lupus erythematosus: an analysis of its systemic manifestations, Ann. Int. Med. 44: 482, 1956. LinkGoogle Scholar8. Dubois EL: The effect of the L. E. cell test on the clinical picture of systemic lupus erythematosus, Ann. Int. Med. 38: 1265, 1953. LinkGoogle Scholar9. Dubois EL: Prednisone and prednisolone in the treatment of systemic lupus erythematosus, J. A. M. A. 161: 427, 1956. Cf: Cohen, H., and Cadman E. F. B.: The natural history of lupus erythematosus and its modification by cortisone, Lancet 2: 305, 1953. CrossrefMedlineGoogle Scholar10. Emerson PA: Pleural effusion complicating rheumatoid arthritis, Brit. M. J. 1: 428, 1956. Cf: Bevans, M., Nadell, J., Demartini, F., and Ragan, C.: The systemic lesions of malignant rheumatoid arthritis, Am. J. Med. 16: 197, 1954. CrossrefMedlineGoogle Scholar11. Falk A: The prognostic significance of idiopathic pleural effusion, Dis. of Chest 18: 542, 1950. CrossrefMedlineGoogle Scholar12. GarlandSisson LHMA: Roentgenologic findings in the "collagen diseases," Am. J. Roentgenol. 71: 58, 1954. Google Scholar13. GouldDaves DMML: Roentgenologic findings in systemic lupus erythematosus: an analysis of 100 cases, J. Chron. Dis. 2: 136, 1955. CrossrefMedlineGoogle Scholar14. GueftLaufer BA: Further cytochemical studies in systemic lupus erythematosus, Arch. Path. 57: 201, 1954. Google Scholar15. HarveyShulmanTumultyConleyShoenrich AMLEPACLEH: Systemic lupus erythematosus: review of the literature and clinical analysis of 138 cases, Medicine 33: 291 (Dec.) 1954. CrossrefMedlineGoogle Scholar16. Haserick JR: Evaluation of three diagnostic procedures for systemic lupus erythematosus, Ann. Int. Med. 44: 497, 1956. LinkGoogle Scholar17. HellerZimmermanRozengvaigSinger PHJSK: The L. E. cell phenomenon in chronic hepatic disease, New England J. Med. 254: 1160, 1956. Cf: Joske, R. A., and King, W. E.: The L. E. cell phenomenon in active chronic viral hepatitis, Lancet 2: 477 (Sept. 3) 1955. CrossrefMedlineGoogle Scholar18. HillKirshbaum HMJD: Miliary tuberculosis developing during prolonged cortisone therapy of systemic lupus erythematosus, Ann. Int. Med. 44: 781, 1956. LinkGoogle Scholar19. HinshawGarland CLH: Diseases of the chest, 1956, W. B. Saunders Co., Philadelphia. Google Scholar20. Israel HL: Pulmonary manifestations of disseminated lupus erythematosus, Am. J. M. Sc. 226: 387, 1953. CrossrefMedlineGoogle Scholar21. Jacobs AG: A false positive L. E. test, Ann. Int. Med. 42: 1097, 1955. Cf: Haverland, H. W.: Presence of L. E. cells in miliary tuberculosis, Am. Rev. Tuberc. 74: 112, 1956. LinkGoogle Scholar22. JessarLamont-HaversRagan RARWC: Natural history of lupus erythematosus disseminatus, Ann. Int. Med. 38: 717, 1953. LinkGoogle Scholar23. KlempererPollackBaehr PADG: Pathology of disseminated lupus erythematosus, Arch. Path. 32: 569, 1941. Google Scholar24. KlempererGueftLeeLeuchtenbergerPollisten PBSLCAW: Cytochemical changes of acute lupus erythematosus, Arch. Path. 49: 503, 1950. Google Scholar25. LeikolaVartia EKO: Lupus erythematosus disseminatus: clinical features and prognosis, Acta Rheum. Scandinav. 1: 73, 1955. CrossrefMedlineGoogle Scholar26. LeuallenCarr ECDT: Pleural effusion: a statistical study of 436 patients, New England J. Med. 252: 79, 1955. CrossrefMedlineGoogle Scholar27. MeachamWeisberger GCAS: Unusual manifestations of disseminated lupus erythematosus, Ann. Int. Med. 43: 143, 1955. LinkGoogle Scholar28. MerrellShulman MLE: Determination of prognosis in chronic disease as illustrated by systemic lupus erythematosus, J. Chron. Dis. 1: 12, 1955. CrossrefMedlineGoogle Scholar29. MoerschPurnellGood HJDCCA: Pulmonary changes occurring in disseminated lupus erythematosus, Dis. of Chest 29: 166, 1956. CrossrefMedlineGoogle Scholar30. MontgomeryMcCreight HWG: Disseminate lupus erythematosus, Arch. Dermat. and Syph. 60: 356, 1949. CrossrefGoogle Scholar31. Moore RA: Textbook of Pathology, 1951, W. B. Saunders Co., Philadelphia. Cf: Herbut, P. A.: Pathology, 1955, Lea and Febiger, Philadelphia; and Anderson, W. A. D.: Textbook of pathology, 1948, C. V. Mosby Co., St. Louis. Google Scholar32. MooreLutz JEWB: Natural history of systemic lupus erythematosus: an approach to its study through chronic benign false positive reactors, J. Chron. Dis. 1: 297, 1955. CrossrefMedlineGoogle Scholar33. PurnellBaggenstossOlsen DCAHAM: Pulmonary lesions in disseminated lupus erythematosus, Ann. Int. Med. 42: 619, 1955. LinkGoogle Scholar34. ReidHutchisonPriceSmith EAJLJDRL: Idiopathic pericarditis, Ann. Int. Med. 45: 88, 1956. LinkGoogle Scholar35. RoperWaring WHJJ: Primary serofibrinous pleural effusion in military personnel, Am. Rev. Tuberc. 71: 616, 1955. MedlineGoogle Scholar36. Rubin EH: The lung as a mirror of systemic disease, 1956, C. C Thomas, Springfield, Illinois. Google Scholar37. Shane SJ: Pleurisy with effusion: its significance and modern treatment, Canad. J. Pub. Health 47: 63, 1956. MedlineGoogle Scholar38. ShearnPirofsky MAB: Disseminated lupus erythematosus, Arch. Int. Med. 90: 790, 1952. CrossrefGoogle Scholar39. SkaggsSmiley JTGW: The course of idiopathic pleural effusion in 50 patients, Am. Rev. Tuberc. 72: 647, 1955. MedlineGoogle Scholar40. SlocumbPolleyWardHench CHHFLEPS: Diagnosis, treatment, and prevention of chronic hypercortisonism in patients with rheumatoid arthritis, Ann. Int. Med. 46: 86, 1957. LinkGoogle Scholar41. SmallLandman MJM: Etiologic diagnosis of pleural effusion by pleural biopsy, J. A. M. A. 158: 907, 1955. CrossrefMedlineGoogle Scholar42. SteadEichenholzStauss WWAHK: Operative and pathological findings in 24 patients with the syndrome of idiopathic pleural effusion, Am. Rev. Tuberc. 71: 473, 1955. MedlineGoogle Scholar43. Thorell I: Pulmonary changes in cases of disseminated lupus erythematosus, Acta radiol. 37: 8, 1952. CrossrefMedlineGoogle Scholar44. Tumulty PA: The clinical course of systemic lupus erythematosus, J. A. M. A. 156: 947, 1954. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication June 24, 1957.From the Division of Pulmonary Diseases, Montefiore Hospital, New York, and the Department of Radiology, New York Hospital.†American Trudeau Society Fellowship, 1955-1956.‡This abbreviation for systemic lupus erythematosus is used throughout this paper.Requests for reprints should be addressed to Lester N. Ploss, M.D., 241 Pennsylvania Ave., Freeport, L. I., N. Y. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySystemic lupus erythematosus presenting as right-sided massive pleural effusion with autoimmune hypothyroidism and medium vessel vasculopathySystemic Lupus Erythematosus and Lung Involvement: A Comprehensive ReviewClinical Aspects of Systemic Lupus ErythematosusThe lung in systemic lupus erythematosusThe Lung in Systemic Lupus ErythematosusPleural EffusionTreatment Considerations of Lung Involvement in Rheumatologic DiseasePulmonary Manifestations of Systemic Lupus Erythematosus (SLE)Derrame pleural refractario en el lupus eritematoso sistémico del niño. Reporte de casoLungPulmonary Manifestations of Systemic Lupus ErythematosusIdiopathic interstitial pneumonias and immunologic diseases of the lungsPleural EffusionPleural EffusionPatient With Bilateral Pleural EffusionResolution of Pleural EffusionsFibrose pulmonar grave: achado incomum em lúpus eritematoso sistêmico: relato de um casoClinical management of the patient with pleural effusionThe American College of Rheumatology criteria for the classification of systemic lupus erythematosus: Strengths, weaknesses, and opportunities for improvementRecurrent right pleural effusion in a young manPULMONARY MANIFESTATIONS OF SYSTEMIC LUPUS ERYTHEMATOSUSAntinuclear Antibodies in Pleural FluidPLEUROPULMONARY MANIFESTATIONS OF SYSTEMIC LUPUS ERYTHEMATOSUSBleeding as the Initial Manifestation of Systemic Lupus ErythematosusConnective Tissue Diseases and the PleuraChanges in clinical features of patients with systemic lupus erythematosus followed prospectively over 2 decadesThe role of thoracoscopy in the diagnosis of pleural pathologyThe role of thoracoscopy in the diagnosis of pleural pathologyPregnancy Complicated by Collagen Vascular DiseaseUtility of serologic testing in the diagnosis of noninfectious pulmonary disordersPulmonary Manifestations of the Collagen Vascular DiseasesSteroid resistant pleural effusion in systemic lupus erythematosus treated with tetracycline pleurodesis.Chest Pain: Cardiac and Noncardiac CausesImmunologic Diseases of the PleuraA comparison of the sensitivity of the 1971 and 1982 american rheumatism association criteria for the classification of systemic lupus erythematosusPulmonary involvement in systemic lupus erythematosus.Pleural EffusionsSystemic Lupus Erythematosus Presenting as Pulmonary HemosiderosisCriteria for the classification of systemic lupus erythematosus—status 1972Diffusionsstörungen bei primär-chronischer Polyarthritis und Lupus erythematodes disseminatusComparative Evaluation of Antinuclear Factor Tests in Rheumatic DisordersPulmonary Dysfunction in Rheumatoid Arthritis and Systemic Lupus ErythematosusPleural effusion with eosinophiliaRHEUMATISM AND ARTHRITIS: REVIEW OF AMERICAN AND ENGLISH LITERATURE OF RECENT YEARS (THIRTEENTH RHEUMATISM REVIEW)*CHARLEY J. SMYTH, M.D., F.A.C.P., ROGER L. BLACK, M.D., FELIX E. DEMARTINI, M.D., IVAN F. DUFF, M.D., F.A.C.P., EPHRAIM P. ENGLEMAN, M.D., F.A.C.P., DONALD C. GRAHAM, M.D., F.R.C.P.(C), MAX M. MONTGOMERY, M.D., F.A.C.P., HOWARD F. POLLEY, M.D., F.A.C.P., EDWARD F. ROSENBERG, M.D., F.A.C.P., CARLOS F. SACASA, M.D., F.A.C.P., OTTO STEINBROCKER, M.D., HANS WAINE, M.D., GEORGE M. WILSON JR., M.D.Lupus erythematosus visceralis 1 July 1958Volume 49, Issue 1Page: 70-88KeywordsArthralgiaArthritisDiagnostic radiologyEmotionsFellowshipsInformation technologyLupus erythematosusPleural effusionPneumonitisPulmonary diseases ePublished: 1 December 2008 Issue Published: 1 July 1958 PDF downloadLoading ...