tbuckley/cabot-search huggingface dataset:
Abstract 234: The Association Between Post--Cardiac Arrest Hemoglobin Levels and Neurological Outcome
Authors: Babette R Rosselot, Anne V Grossestreuer, Nora L Lee, Kalani Dodampahala, Munish Goyal, Abel David, Benjamin S Abella, David F Gaieski
Journal: Circulation (2014)

Background: Inadequate cerebral oxygenation is a risk factor for neurologic damage in successfully resuscitated cardiac arrest patients. One therapy to address this problem is early goal-directed hemodynamic optimization. However, the role of hemoglobin (Hgb) levels, a potential target for optimization, on outcomes in post-cardiac arrest patients is not known. Objective: To determine the association between Hgb levels in post-cardiac arrest patients and neurologic outcome (dichotomized into “good,” a Cerebral Performance Category (CPC) of 1 or 2 and “poor,” a CPC of 3, 4, or 5, at hospital discharge). The association between Hgb levels and survival to discharge was analyzed as a secondary outcome. Methods: A retrospective cohort study was conducted to compare patient demographics and Hgb levels. Hgb was analyzed as both a continuous and binary variable. To determine the association between Hgb levels and outcomes, multivariate logistic regression models controlling for gender, age, pulseless rhythm, and transfusion were used. Results: There were 598 eligible subjects from 21 hospitals in the US. Patients with ≤10 g/dL of Hgb had a higher percentage of subjects with good neurologic outcome than those with Hgb levels below 10 g/dL (41% vs. 26%; p &lt; 0.001). Patients with good neurologic outcome had higher median Hgb levels in the first six hours after arrest than those with a poor neurologic outcome (12.6 g/dL vs. 10.5 g/dL; p &lt; 0.001). Controlling for gender, age, pulseless rhythm, and transfusion, there was a significant relationship between Hgb levels within the first six hours after arrest and good neurologic outcome (OR: 1.21, 95% CI: 1.06 [[Unable to Display Character: &amp;#8211;]] 1.39) and the first 24 hours after arrest and good neurologic outcome (OR: 1.14, 95% CI: 1.01 [[Unable to Display Character: &amp;#8211;]] 1.28). There was a significant association between Hgb levels within the first six hours after arrest and survival to discharge (OR: 1.22, 95% CI: 1.07 [[Unable to Display Character: &amp;#8211;]] 1.39) and Hgb levels within the first 24 hours after arrest and survival to discharge (OR: 1.14, 95% CI: 1.02 [[Unable to Display Character: &amp;#8211;]] 1.28). Conclusions: Higher hemoglobin levels, particularly within the first six hours after cardiac arrest, are associated with better neurologic outcomes at hospital discharge in post-cardiac arrest patients admitted to the hospital.
234. Correction of Pathology in Galactosialidosis Mice Crossed into Transgenic Mice Expressing PPCA in Neural Cells
Authors: Huimin Hu, Linda Mann, Erik Bonton, Taylor Walker, Alessanrdra d'Azzo
Journal: Molecular Therapy (2004)

Protective protein/cathepsin A (PPCA) is a lysosomal carboxypeptidase that is deficient in Galactosialidosis (GS), an autosomal recessive, neurodegenerative lysosomal disorder affecting most of the systemic organs and the central and peripheral nervous systems. The GS mouse model resembles closely the severe human condition and develops a progressive neurological phenotype including loss of hearing and motor coordination.
CLINICAL STUDIES IN RENAL DISEASE. III. ACIDOSIS IN CHRONIC GLOMERULONEPHRITIS
Authors: Eugene R. Marzullo
Journal: Annals of Internal Medicine (1940)

Article1 March 1940CLINICAL STUDIES IN RENAL DISEASE. III. ACIDOSIS IN CHRONIC GLOMERULONEPHRITISEUGENE R. MARZULLO, M.D., F.A.C.P.EUGENE R. MARZULLO, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-13-9-1638 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptUremia is a toxic state associated with an abnormal accumulation of nitrogen bodies in the blood. It is characterized clinically by anorexia, nausea, vomiting, weakness, restlessness, headache, drowsiness or coma. The exact nature of the toxemia of uremia is not known, although such substances as urea, uric acid, creatinine, phosphates, sulphates are present in the blood in excessive amounts. It was Bright himself who first designated as uremia the group of symptoms characteristic of renal failure, because he thought these symptoms were due to a retention of urea in the blood. Bright regarded urea as a highly toxic substance but...References1. VON JAKSCH R: Ueber die Alkalescenz des Blutes bei Krankheiten, Ztschr. f. klin. Med., 1888, xiii, 350. Google Scholar2. PETERSVAN SLYKE JDD: Quantitative clinical chemistry, 1931, i, 984. Google Scholar3. PLOTZHOWARDMARZULLO MTER: Treatment in advanced nephritis, Internat. Clin., 1937, i, 17. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Brooklyn, New York*Received for publication November 6, 1937.From the Medical Department of the Long Island College of Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 March 1940Volume 13, Issue 9Page: 1638-1643KeywordsBloodGlomerulonephritisHeadachesNauseaPhosphatesRenal diseasesRenal failureUreaUric acidVomiting ePublished: 1 December 2008 Issue Published: 1 March 1940 PDF downloadLoading ...
Abstract 1456: MicroRNA improves the efficacy of imatinib on the treatment of chronic myeloid leukemia
Authors: Bin Yi, Ruixia Ma, Xiangling Feng, Zhiwei Xing, Xiaoguo Zhang, Gary Piazza, Yaguang Xi
Journal: Cancer Research (2014)

Abstract Human chronic myelogenous leukemia (CML) is a malignancy of pluripotent hematopoietic cells that is caused by the deregulated activity of the tyrosine kinase that is encoded by the chimeric bcr-abl oncogene. Given that CML cells are usually highly resistant to chemotherapy, novel and more efficacious strategies against this disease are urgently needed. MicroRNA (miRNA) is a set of newly discovered 20-22 nucleotides RNA molecules, and they broadly repress their cognate target genes at post-transcriptional/trans-lational level. To date, there are approximately 2,500 human miRNA transcripts have been characterized, which are estimated to modulate more than 30% human genes by being involved in many essential normal biological and pathological processes including differentiation, proliferation, apoptosis, and tumorigenesis as well. In this study, we studied let-7a, a miRNA with tumor suppressive signature, for its therapeutic potential in CML. When treating CML K562 and KU812 cell by imatinib, let-7a can be significantly induced. Overexpression of let-7a can sensitize K562 and KU812 cells to imatinib, while knock-down of let-7a can increase the resistance of these cells towards this drug. The functional studies found that let-7a was able to promote apoptosis of CML cells, inhibit the tumor cell proliferation, and lead to a cell cycle arrest in the G0/G1 phase. These results demonstrate that let-7a is a potential target for treating CML by imatinib and/or other anti-cancer drugs. The pro-apoptosis and anti-proliferation roles of let-7a in CML cells may provide novel insights into discovery and development of more efficacious drugs for treating this malignant disease. Citation Format: Bin Yi, Ruixia Ma, Xiangling Feng, Zhiwei Xing, Xiaoguo Zhang, Gary Piazza, Yaguang Xi. MicroRNA improves the efficacy of imatinib on the treatment of chronic myeloid leukemia. [abstract]. In: Proceedings of the 105th Annual Meeting of the American Association for Cancer Research; 2014 Apr 5-9; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2014;74(19 Suppl):Abstract nr 1456. doi:10.1158/1538-7445.AM2014-1456
Incidence of and Risk Factors for Sudden Cardiac Death in Children With Dilated Cardiomyopathy
Authors: Elfriede Pahl, Lynn A. Sleeper, Charles E. Canter, Daphne T. Hsu, Minmin Lu, Steven A. Webber, Steven D. Colan, Paul F. Kantor, Melanie D. Everitt, Jeffrey A. Towbin, John L. Jefferies, Beth D. Kaufman, James D. Wilkinson, Steven E. Lipshultz
Journal: Journal of the American College of Cardiology (2012)
Marine-Derived n-3 Fatty Acids and Atherosclerosis in Japanese, Japanese-American, and White Men
Authors: Akira Sekikawa, J. David Curb, Hirotsugu Ueshima, Aiman El-Saed, Takashi Kadowaki, Robert D. Abbott, Rhobert W. Evans, Beatriz L. Rodriguez, Tomonori Okamura, Kim Sutton-Tyrrell, Yasuyuki Nakamura, Kamal Masaki, Daniel Edmundowicz, Atsunori Kashiwagi, Bradley J. Willcox, Tomoko Takamiya, Ken-ichi Mitsunami, Todd B. Seto, Kiyoshi Murata, Roger L. White, Lewis H. Kuller
Journal: Journal of the American College of Cardiology (2008)
Abstract 57: Bystander Chest Compression-Alone Cardiopulmonary Resuscitation (CPR) For Patients With Out-Of-Hospital Cardiac Arrest Due To Non-Cardiac Causes
Authors: Ken Nagao, Tetsuya Sakamoto, Masaki Igarashi, Shinichi Ishimatsu, Akira Sato, Shingo Hori, Shigeru Kanesaka, Yuichi Hamabe, Kimio Kikushima, Shinya Kitamura
Journal: Circulation (2006)

BACKGROUND Few clinical studies have focused on the efficacy of the technique of bystander CPR for patients with asphyxial arrest. In the 2005 AHA, we presented that bystander chest compression-alo...
Third-party-mediated graft rejection and graft-versus-host disease after T-cell-depleted bone marrow transplantation, as demonstrated by hypervariable DNA probes and HLA-DR polymorphism
Authors: W Drobyski, S Thibodeau, RL Truitt, LA Baxter-Lowe, J Gorski, R Jenkins, J Gottschall, RC Ash
Journal: Blood (1989)
Abstract P319: Randomized Trial of a Multivitamin Supplement on Risk of Hypertension and Blood Pressure Change Among Middle-Aged and Older Men
Authors: Lu Wang, Susanne Rautiainen, JoAnn E Manson, Julie E Buring, Robert J Glynn, J. Michael Gaziano, Howard Sesso
Journal: Circulation (2015)

Background: Adequate intake of selected vitamins and minerals has been hypothesized to lower blood pressure (BP). However, no randomized, controlled trial has specifically examined the effect of a multivitamin supplement, commonly used in the US, on BP and risk of developing hypertension. Design: In the Physicians’ Health Study II - a randomized, double-blind, placebo-controlled trial of a daily multivitamin supplement among 14,641 men initially aged ≥50 years, systolic BP (SBP), diastolic BP (DBP), and use of antihypertensive medications was reported on baseline and annual follow-up questionnaires. Changes in BP from baseline were assessed at 36, 72, and 96 months, and at the end of the intervention. Incident hypertension was defined as self-reported SBP ≥140 mmHg, DBP ≥90 mmHg, or initiation of anti-hypertensive medication during follow-up that continued through June 1, 2011. Results: Among 8,458 men free of hypertension at baseline (mean age: 62.1±8.5 years), 1,808 of 4,263 in the active multivitamin s...
Beat Goes On in "Off-Pump" Bypass Surgery
Authors: Mike Mitka
Journal: JAMA (2004)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Multiple Myeloma—Better Drugs Ask for More Stringent Evaluations
Authors: Pieter Sonneveld
Journal: JAMA Oncology (2015)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Oncology HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Oncology journal
Abstract 12926: Transition Readiness Assessment in Adolescents and Young Adults With Heart Disease: Can We Improve the Outcome?
Authors: Karen Uzark, Cynthia Smith, Sunkyung Yu, Janet Donohue, Katherine Afton, Mark D Norris, Timothy B Cotts
Journal: Circulation (2014)

Objective: Transition is defined as “the process by which adolescents and young adults with chronic childhood illnesses are prepared to take charge of their lives and their health in adulthood”. We previously reported common knowledge deficits and lack of transition readiness (TR) in 13-25 year olds with congenital or acquired heart disease. The aims of this study were to re-evaluate TR in these patients at follow-up (F/U) and to examine the relationship between changes in TR and quality of life (QOL). Methods: Patients (n=106) completed the TR Assessment and Pediatric Quality of Life Inventory (PedsQL) utilizing an e-tablet, web-based format at a routine F/U clinic visit. Changes from initial to F/U scores were evaluated. Results: Median patient age was 18.7 yrs at a median F/U time of 1.02 yrs. Average perceived knowledge deficit score (% of items with no knowledge) at F/U was 18.0 ± 15.2%, decreased from 24.7 ± 16.5%, p&lt;.0001. On a 100-point scale, the mean score for self-efficacy increased from 71.4 ± 17.0 to 76.7 ± 18.2 (p=.004) and for self-management increased from 47.9 ± 18.4 to 52.0 ± 20.7 (p=.0004). While physical QOL did not change, the mean psychosocial QOL score increased significantly from 80.2 ± 13.3 to 82.5 ± 12.0, p=.02. A decrease in knowledge deficit score at F/U was significantly associated with an increased psychosocial QOL score, p=.03. An increase in self-efficacy score was associated with an increase in psychosocial QOL score (p=.04), especially social QOL (p=.02). Among patients who reported receiving specific information after initial TR assessment, knowledge deficits decreased related to medication (p=.002), symptoms to call for (p=.02), how to contact heart doctor (p=.02), and health insurance (p=.10). Self-efficacy scores improved in patients reporting receipt of information regarding how to contact the heart doctor (p=.06) and how to communicate with healthcare team (p=.05). Conclusion: While deficits in knowledge and self-management skills persist, TR assessment and recognition of deficits can improve transition readiness with improved psychosocial QOL. Routine TR assessment is important to identify transition needs. Further studies are needed to examine the relationship between TR and outcomes in young adults with heart disease.
Abstract 17191: Fragmentation Assessed by Magnetocardiography but not Electrocardiogram Can Predict Future Cardiac Events in Patients with Non-ischemic Dilated Cardiomyopathy and Narrow QRS
Authors: Shoji Kawakami, Hiroshi Takaki, Shuji Hashimoto, Mitsuru Wada, Kohei Ishibashi, Ikutaro Nakajima, Koji Miyamoto, Hideo Okamura, Takashi Noda, Takeshi Aiba, Kengo Kusano, Satoshi Yasuda, Hisao Ogawa, Shiro Kamakura, Masaru Sugimachi
Journal: Circulation (2014)

Background: Fragmented QRS (fQRS) in 12-lead ECG, ascribed to myocardial scar, has been shown to predict future cardiac events in patients with both ischemic and non-ischemic dilated cardiomyopathy (NIDCM). Various definitions and low specificity of fQRS, however, limited its use. We hypothesized that the advantage of 64-channel magnetocardiography (MCG), i.e., high spatio-temporal resolution, enables more accurate detection of fragmented LV conduction (fLV), that would lead to accurate prediction of future events. Methods: In 51 patients with NIDCM and narrow QRS (LVEF, 22±7%; QRS duration, 99±11 ms), we recorded MCG. We defined, in MCG superimposed vector magnitude waveforms, fLV as distinct abnormal components (&gt;20% of maximal amplitude). In current arrow map, fLV corresponded to heterogeneous QRS currents (Figure). We predicted major adverse cardiac events (MACE), including sudden cardiac death (SCD), sustained ventricular tachyarrhythmias (VF/VT), appropriate defibrillator discharge (Def) and left ventricular assist device implantation (LVAD). Results: fLV was present in 27 (Group-F) and not in 24 (Group-N). Age, gender, ECG and echocardiographic findings, laboratory data and medications were similar irrespective of fLV. During a mean follow-up of 2.2 years, MACE occurred in 19 (4 SCD, 9 VF/VT, 2 Def, and 4 LVAD). MACE more frequently occurred with fLV (63%, 17/27) than without (8%, 2/24, Kaplan-Meier analysis, p&lt;0.001). Multivariate analysis revealed fLV as the only independent predictor of MACE (HR 4.82, p=0.015). Conclusion: MCG analysis is a promising noninvasive tool to accurately detect fragmentation and predict MACE in patients with NIDCM and normal QRS.
THE INHALATION OF DUST PENICILLIN
Authors: L KRASNO, M KARP, P S RHOADS
Journal: Annals of Internal Medicine (1948)

Article1 March 1948THE INHALATION OF DUST PENICILLINLOUIS KRASNO, Ph.D., M.D., MARY KARP, M.D., PAUL S. RHOADS, M.D., F.A.C.P.LOUIS KRASNO, Ph.D., M.D.Search for more papers by this author, MARY KARP, M.D.Search for more papers by this author, PAUL S. RHOADS, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-28-3-607 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn view of the favorable reports in recent literature on the inhalation of therapeutic agents, especially penicillin, and because of the many possibilities of the method, we have attempted to produce even greater and more protracted topical effectiveness by a method which involves the inhalation of fine dust aerosol particles. This method has simplified the mechanics of aerosol therapy, thus expanding its scope more readily for office and home treatment.Aerosols may be defined as suspensions of liquids or solids in air or oxygen. In the past, the aerosolization methods have included only the inhalation of suspensions of liquids. The...Bibliography1. HEILMANHERRELL SHWE: The use of Fleming's modification of the Wright slide call technic for determining penicillin in body fluids, Am. Jr. Clin. Path., 1945, xv, 7. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Chicago, Illinois*Received for publication June 6, 1947.From the Division of Surgery, Northwestern University Medical School and Department of Anesthesiology, Wesley Memorial Hospital (Dr. Karp). From the Division of Medicine, Northwestern University Medical School (Dr. Rhoads, Professor of Medicine).†The penicillin for this study was especially processed by, and furnished through the courtesy of Abbott Laboratories, North Chicago, Illinois. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byACUTE SUPPURATIVE BRONCHITIS AND BRONCHIOLITIS IN CHRONIC PULMONARY DISEASE: DIAGNOSIS AND MANAGEMENT*LEONARD CARDON, M.D., F.A.C.P., LOUIS LEMBERG, M.D., REGINA S. GREENEBAUM, M.D.Broncho-EsophagologyNIPPLE-SHIELDSAEROSOLS BY INHALATIONTHE DOCTOR'S CREEDThe inhalation of 1-(3′,4′-dihydroxyphenyl)-2-isopropylaminoethanol (Norisodrine sulfate dust)Management of Nontuberculous Bronchopulmonary SuppurationsThe Inhalation of Norisodrine Sulfate Dust 1 March 1948Volume 28, Issue 3Page: 607-617KeywordsAnesthesiologyDustInhalationOxygenPenicillinSurgery ePublished: 1 December 2008 Issue Published: 1 March 1948 PDF downloadLoading ...
An International Recommendation for Quantities and Units in Clinical Chemistry
Authors: R Dybkaer
Journal: Annals of Internal Medicine (1968)

Special Articles1 September 1968An International Recommendation for Quantities and Units in Clinical ChemistryRENÉ DYBKAER, M.D.RENÉ DYBKAER, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-69-3-621 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe Commission on Clinical Chemistry (CCC) of the International Union of Pure and Applied Chemistry (IUPAC) nominated a Subcommission for Standards and Units in Clinical Chemistry* in 1965. The primary task of the subcommission was to study [1] individual and national efforts to counteract the increasingly chaotic use of quantities and units in clinical chemistry; [2] current usage of units in related fields of science, especially biochemistry and general chemistry; and [3] the official recommendations regarding units from IUPAC, IUB†, IUPAP‡, and ISO§. The subcommission was also to submit a draft for a CCC Recommendation.An intermediate result,A Primer...References1. DYBKAER R and JØRGENSEN K: A Primer of Quantities and Units in Clinical Chemistry, made on behalf of the Subcommittee for Standardization of Units in Clinical Chemistry of IFCC, Copenhagen, 1966, 25 pages. Google Scholar2. DYBKAER R and JØRGENSEN K: Quantities and Units in Clinical Chemistry, including Recommendation 1966 of the Commission on Clinical Chemistry of the International Union of Pure and Applied Chemistry and of the International Federation for Clinical Chemistry, Munksgaard, Copenhagen, 1967, 112 pages. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: RENÉ DYBKAER, M.D.Affiliations: Copenhagen,From the Commission on Quantities and Units in Clinical Chemistry of the International Union of Pure and Applied Physics; and the International Federation for Clinical Chemistry.Requests for reprints should be addressed to René Dybkaer, M.D., University Institute of Medical Microbiology, 22 Juliane Mariesvej, DK 2100 Copenhagen Ø, Denmark.*J. E. Courtois, president (Paris), R. Dybkaer and P. Lous (Copenhagen), N. F. Maclagan (London), M. Rubin (Washington, D. C.), and M. C. Sanz (Geneva).†International Union of Biochemistry.‡International Union of Pure and Applied Physics.§International Organization for Standardization.∥Australia, Belgium, Canada, Czechoslovakia, Denmark, Federal Republic of Germany, Finland, France, Iran, Japan, Netherlands, Norway, Sweden, Switzerland, UK, USA, and USSR.**International Federation for Clinical Chemistry. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 September 1968Volume 69, Issue 3Page: 621-623KeywordsBiochemistryClinical chemistry ePublished: 1 December 2008 Issue Published: 1 September 1968 PDF downloadLoading ...