TOXICITY OF THIOCYANATES USED IN TREATMENT OF HYPERTENSION
Authors: W F GERMAN, E MESSINGER, M HERMAN
Journal: Annals of Internal Medicine (1949)

Case Reports1 May 1949TOXICITY OF THIOCYANATES USED IN TREATMENT OF HYPERTENSIONWARREN F. GORMAN, M.D., EMANUEL MESSINGER, M.D., MORRIS HERMAN, M.D.WARREN F. GORMAN, M.D., EMANUEL MESSINGER, M.D., MORRIS HERMAN, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-30-5-1054 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe purpose of this article is to describe the toxic effects of thiocyanate as used in the treatment of hypertension, and to report a fatal case of thiocyanate poisoning.HISTORY AND GENERAL USAGEThe popularity of thiocyanate (SCN) treatment for hypertension has fluctuated over a period of years. The drug was first studied from a pharmacological standpoint in 1857 by Claude Bernard, but it was not until 1903 that Pauli made use of its hypotensive properties in clinical medicine. In 1925, Westphal commented on its toxic effects. 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Y.*Received for publication December 30, 1947.From the Departments of Psychiatry and Neurology, New York University College of Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byIn Vivo Growth Inhibition of Human Caucasian Prostate Adenocarcinoma in Nude Mice Induced by Amygdalin with Metabolic Enzyme CombinationsConducting polyaniline nanotubes with silver nanoparticles in the separation of thiocyanate from aqueous mediaKonzo risk factors, determinants and etiopathogenesis: What is new? 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