THE EFFECT OF ANTICOAGULANT THERAPY UPON THE DEVELOPMENT OF MURAL THROMBOSIS FOLLOWING MYOCARDIAL INFARCTION
Authors: D HOWELL, F A KYSER
Journal: Annals of Internal Medicine (1954)

Article1 April 1954THE EFFECT OF ANTICOAGULANT THERAPY UPON THE DEVELOPMENT OF MURAL THROMBOSIS FOLLOWING MYOCARDIAL INFARCTIONDAVID HOWELL, M.D., FRANKLIN A. KYSER, M.D., F.A.C.P.DAVID HOWELL, M.D., FRANKLIN A. KYSER, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-40-4-694 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptMany studies have been reported indicating the frequency with which mural thrombosis occurs as a result of infarction of the heart.1, 2, 3 The embolic complications resulting from such thrombi have been discussed in numerous reports,3, 4, 5 including successful attempts at preventing mural thrombosis in experimental animals by the administration of anticoagulant drugs.6, 7, 8Wright9recently indicated that anticoagulant therapy is of value in preventing mural thrombosis following myocardial infarction. We are unaware of any published reports noting specifically the incidence of mural thrombosis in patients who have received anticoagulant drugs during convalescence from myocardial infarction, and it...Bibliography1. Bean WB: Infarction of the heart. III. Clinical course and morphologic findings, Ann. Int. Med. 12: 71, 1938. LinkGoogle Scholar2. JordonMillerEdwardsParker RARDJERL: Thromboembolism in acute and healed myocardial infarction. I. Intracardiac mural thrombosis, Circulation 6: 1, 1952. CrossrefMedlineGoogle Scholar3. RublerAngrist SAA: A study of mural thrombi in myocardial infarction as a source of embolization, Am. J. M. Sc. 225: 20, 1953. CrossrefMedlineGoogle Scholar4. NayBarnes RMAR: Incidence of embolic or thrombotic processes during the immediate convalescence from myocardial infarction, Am. Heart J. 30: 65, 1945. CrossrefGoogle Scholar5. MillerJordonParkerEdwards RDRARLJE: Thromboembolism in acute and in healed myocardial infarction. II. Systemic and pulmonary arterial occlusion, Circulation 6: 7, 1952. CrossrefMedlineGoogle Scholar6. SolandtMassinBest , quoted by Wright, I. S.: The modern treatment of coronary thrombosis with myocardial infarction, Circulation 2: 929, 1950. CrossrefGoogle Scholar7. RobergRequarthe NWH: Heparin in experimental myocardial infarction, Circulation 1: 1193, 1950. CrossrefMedlineGoogle Scholar8. BeattieCutlerFauteuzKinneyLevine EJECMTDHD: The use of Dicumarol in experimental coronary occlusion, Am. Heart J. 34: 94, 1948. CrossrefGoogle Scholar9. Wright IS: Anticoagulant treatment of myocardial infarction (a summary of the final report of the Committee on Anticoagulants of the American Heart Association), read at the Annual Meeting of the American College of Physicians, Atlantic City, New Jersey, April, 1953. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication October 28, 1953.From the Department of Medicine, Northwestern University Medical School, and the Evanston Hospital.Read before the Midwest Regional Meeting of the American College of Physicians, Milwaukee, Wisconsin, November 21, 1953. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byMassive Thrombosis of the Left VentricleHÆMOPERICARDIUM COMPLICATING ANTICOAGULANT THERAPYDie Coronarerkrankungen. Coronarinsuffizienz, Angina pectoris und HerzinfarktThe influence of anticoagulant therapy on the occurrence of cardiac rupture and hemopericardium following heart infarction. II. A controlled study of a selected treated group based on 1,044 autopsiesAnticoagulant therapy of acute myocardial infarctionThe Prevention of Thromboembolic Complications in Myocardial Infarction by Anticoagulant Therapy 1 April 1954Volume 40, Issue 4Page: 694-697KeywordsAnticoagulant therapyAnticoagulantsConvalescenceDrug administrationDrug therapyHospital medicineInfarctionLongitudinal studiesMyocardial infarctionThrombosis ePublished: 1 December 2008 Issue Published: 1 April 1954 PDF downloadLoading ...