THE INTERRELATIONSHIPS BETWEEN ADDISON'S DISEASE AND ACTIVE TUBERCULOSIS: A REVIEW OF 125 CASES OF ADDISON'S DISEASE
Authors: J P SANFORD, C B FAVOUR
Journal: Annals of Internal Medicine (1956)

Article1 July 1956THE INTERRELATIONSHIPS BETWEEN ADDISON'S DISEASE AND ACTIVE TUBERCULOSIS: A REVIEW OF 125 CASES OF ADDISON'S DISEASEJ. P. SANFORD, C. B. FAVOURJ. P. SANFORDSearch for more papers by this author, C. B. FAVOURSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-45-1-56 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe difficulties of evaluating the effect of adrenal function on the course of an infection are well illustrated in the clinical problem presented by the spontaneous occurrence of active tuberculosis in the presence of Addison's disease. The purpose of the present report is to describe certain complexities in this relationship observed in a series of patients with adrenal insufficiency who have been followed over the past 20 years.Endocrines and Infection:The effects of hormonal balances on infectious processes, and on tuberculosis in particular, have long been a field of interest. Studies on the influence of diabetes1-4and of pregnancy...Bibliography1. Root HF: The association of diabetes and tuberculosis, New England J. Med. 210: 1, 1934. CrossrefGoogle Scholar2. Banyai AL: Diabetes and pulmonary tuberculosis, Am. Rev. Tuberc. 24: 650, 1931. Google Scholar3. RootBloor HFWR: Diabetes and pulmonary tuberculosis, Am. Rev. Tuberc. 39: 714, 1939. Google Scholar4. Joslin EP: The treatment of diabetes mellitus, 1928, Lea and Febiger, Philadelphia. Google Scholar5. BridgemanNorwood EWV: Pulmonary tuberculosis and pregnancy, Bull. Johns Hopkins Hosp. 38: 83, 1926. Google Scholar6. 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Author, Article, and Disclosure InformationAffiliations: *Received for publication March 17, 1956.Work done under USPHS grants E-32(C) and E-941.From the Medical Clinics of the Peter Bent Brigham Hospital, the Department of Medicine, Harvard Medical School, Boston, Massachusetts.Requests for reprints should be addressed to Jay P. Sanford, Capt., MC, Dept. Experimental Surgery, Walter Reed Army Institute of Research, Walter Reed Army Medical CenterWashington 12, D. C.†Work completed during the tenure of a Public Health Service Fellowship of the National Institutes of Health. 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