tbuckley/cabot-search huggingface dataset:
Quantifying cardiovascular disease risk factors in patients with psoriasis: a meta-analysis
Authors: I.M. Miller, T. Skaaby, C. Ellervik, G.B.E. Jemec
Journal: British Journal of Dermatology (2013)

In a previous meta-analysis on categorical data we found an association between psoriasis and cardiovascular disease and associated risk factors.To quantify the level of cardiovascular disease risk factors in order to provide additional data for the clinical management of the increased risk.This was a meta-analysis of observational studies with continuous outcome using random-effects statistics. A systematic search of studies published before 25 October 2012 was conducted using the databases Medline, EMBASE, International Pharmaceutical Abstracts, PASCAL and BIOSIS.We included 59 studies with up to 18 666 cases and 50 724 controls. Psoriasis cases had a higher total cholesterol [weighted mean difference 8·83 mg dL(-1) , 95% confidence interval (CI) 2·94-14·72, P = 0·003 (= 0·23 mmol L(-1) )], higher low-density lipoprotein cholesterol [9·90 mg dL(-1) , 95% CI 1·56-18·20, P = 0·020 (= 0·25 mmol L(-1) )], higher triglyceride [16·32 mg dL(-1) , 95% CI 12·02-20·63, P < 0·001 (= 0·18 mmol L(-1) )], a higher systolic blood pressure (4·77 mmHg, 95% CI 1·62-7·92, P = 0·003), a higher diastolic blood pressure (2·99 mmHg, 95% CI 0·60-5·38, P = 0·014), higher body mass idex (0·73 kg m(-2) , 95% CI 0·37-1·09, P < 0·001), higher waist circumference (3·61 cm, 95% CI 2·12-5·10, P < 0·001), higher fasting glucose [3·52 mg dL(-1) , 95% CI 0·64-6·41, P = 0·017 (= 0·20 mmol L(-1) )], higher nonfasting glucose [11·70 mg dL(-1) , 95% CI 11·24-12·15, P < 0·001 (= 0·65 mmol L(-1) )] and a higher HbA1c [1·09 mmol mol(-1) , 95% CI 0·87-1·31, P < 0·001 (= 2·2%)].From a preventive medicine perspective, the weighted mean differences between cases and controls are significant, and therefore relevant to the clinical management of patients with psoriasis.
Tänzerische Heilgymnastik mit Schizophrenen
Authors: S. Haddenbrock
Journal: Psychotherapy and Psychosomatics (1959)

Research Articles| February 10 2010 Tänzerische Heilgymnastik mit Schizophrenen Subject Area: Psychiatry and Psychology S. Haddenbrock S. Haddenbrock Schussenried/Württ Search for other works by this author on: This Site PubMed Google Scholar Acta Psychotherapeutica et Psychosomatica (1959) 7 (Suppl. 1): 150–154. https://doi.org/10.1159/000285432 Article history Published Online: February 10 2010 Content Tools Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation S. Haddenbrock; Tänzerische Heilgymnastik mit Schizophrenen. Acta Psychotherapeutica et Psychosomatica 1 January 1959; 7 (Suppl. 1): 150–154. https://doi.org/10.1159/000285432 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsActa Psychotherapeutica et Psychosomatica Search Advanced Search Article PDF first page preview Close Modal This content is only available via PDF. 1959Copyright / Drug Dosage / DisclaimerCopyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. You do not currently have access to this content.
Agencies prepare to deal with mental health problems in Libya after 42 years of repression
Authors: S. Arie
Journal: BMJ (2011)

<h3>ABSTRACT</h3> The present study explored the microprobe X-ray fluorescence spectroscopy (µ-XRF) for quantitative and space-resolved distribution of macro, <i>i</i>.<i>e</i>., K, P, S, and Ca, and micronutrients, <i>i</i>.<i>e</i>., Fe, Zn, and Mn elemental composition in the cross-sectioned seeds of cowpea (<i>Vigna unguiculata</i> L.), kidney bean (<i>Phaseolus vulgaris</i> L.), and soybean <i>(Glycine max</i> L.) seeds, important agricultural species within the Fabaceae family. It unveils that both macro and micronutrients were heterogeneously distributed across seed tissues. Most of the P and S, Fe, Zn, and Mn were mainly found at the embryo axis tissues in all three Fabaceae species, whereas K was spread along the cotyledon and Ca was mostly observed trapped at the seed coat region. Furthermore, the Pearson correlation coefficient revealed a strong spatial correlation between P and S, and K and S in cowpea and soybean seed tissues, whereas Zn and Mn association was also recorded. Therefore, the µ-XRF technique demonstrates to be an important tool for assessing seed nutrient distribution, thus subsidizing the understanding of the physiological role of nutrients in seeds and fostering innovative approaches for nutrient supply and biofortification.
Are All Baby Foods Special Dietary Foods?
Authors: Fredrick J. Stare, Charles A. Janeway
Journal: New England Journal of Medicine (1967)

THE Food and Drug Administration is presently revising the regulations for food for special dietary uses. There is no doubt that there are certain aspects of the regulations that need revision to protect the consumer. Examples of needed regulations are the many ridiculous multivitamin and mineral supplements available from the mail-order "health-food" shops and the increasing number of foods that are "lower" in calories, but really not very low.We are disturbed however by the interpretation that may be given by those responsible for enforcement to the definition of Special Dietary Foods, which would place ordinary "baby foods" in this . . .
Transrectal ultrasound study of the pathogenesis of solitary rectal ulcer syndrome.
Authors: M J Van Outryve, P A Pelckmans, H Fierens, Y M Van Maercke
Journal: Gut (1993)

Transrectal ultrasonography is of clinical value in anorectal carcinoma and in inflammatory diseases of the anorectum. In this study a rigid linear endorectal probe was used to examine 15 patients with endoscopically and biopsy proved diagnosis of solitary rectal ulcer syndrome. In 13 of the 15 patients the rectal wall was thicker (mean (SEM) 5.7 (0.4) mm; normal values: 2.8 (0.1) mm) near the rectal ulcer. In all these cases the muscularis propria layer exceeded the maximum normal diameter of 2 mm. In nine of the 15 patients the normal rectal wall echo-structure, with five distinct layers, was disturbed and there was fading of the borders between the mucosa and the muscularis propria. Poor relaxation of the puborectalis muscle during straining was seen on ultrasound in 11 patients, as was intussusception of the rectal wall. The obvious enlargement of the muscularis propria points to a chronic mechanical load on the rectal wall. The ulcerative lesions are formed in this area of overloaded rectal wall. The direct visualisation of the puborectalis muscle during dynamic transrectal ultrasonography indicates that the fact that it does not relax is an important element in the pathogenesis of solitary rectal ulcer syndrome.
Clinicopathologic Correlation of Ocular Disease: A Text and Stereoscopic Atlas
Authors: J. Brooks Crawford
Journal: JAMA (1979)

The second edition of this book has been extensively revised and expanded from the first edition, which appeared four years earlier. In the previous edition, the lens and glaucoma were combined in a single chapter; retinoblastoma, phakomatoses, and the optic nerve were included in the chapter on fundus diseases. In the new edition, a separate chapter is devoted to each of these important topics, making the book 97 pages longer (and more expensive). The reproductions of black-and-white clinical photographs and photomicrographs are better in this edition. In general, the photomicrographs are well chosen and accurately labeled. Tables, diagrams, and schematic drawings are excellent. The text is well organized, clear, concise, and a pleasure to read. The references are relatively complete and up-to-date. The book covers the material presented in an unusually good basic science course in ophthalmic pathology. It is for the student of ophthalmology and the clinician who is
Modification of Aortic Oxidative Enzymes in Rats by Gonadectomy and Substitutive Therapy
Authors: Manuel Rene Malinow, Jaime Alberto Moguilevsky, Jorge Luis Lacuara
Journal: Circulation Research (1962)

Activity of the following enzyme systems has been determined in homogenates of aortas from rats: "succinic dehydrogenase," cytochrome oxidase, oxidation of α-ketoglutaric acid and of fumaric acid, DPN- and TPN-linked dehydrogenases, as well as lactic dehydrogenase. The following groups of animals were studied: (1) intact males; (2) castrated males; (3) castrated males injected with testosterone; (4) intact females; (5) spayed females; (6) spayed females injected with estradiol. Results demonstrated that gonadectomy in males stimulated "succinic dehydrogenase" and depressed the oxidation of fumaric acid; these effects were reversed by the injection of testosterone. Castration did not modify the activity of cytochrome oxidase, oxidation of α-ketoglutaric acid, DPN- and TPN-linked dehydrogenases, nor lactic dehydrogenase. Gonadectomy in females resulted in stimulation of "succinic dehydrogenase," cytochrome oxidase, as well as oxidation of α-ketoglutaric acid; these effects were reversed by the injection of estradiol into spayed females. No clear results were obtained in connection with oxidation of fumaric acid and no modifications were observed in the activity of DNP- and TPN-linked dehydrogenases nor in lactic dehydrogenase. Experiments performed in vitro showed that sexual hormones were able to depress the activity of oxidative systems in aortic homogenates.
Asplenia and Rheumatoid Arthritis
Authors: DALA R. JAROLIM
Journal: Annals of Internal Medicine (1982)

Letters and Corrections1 October 1982Asplenia and Rheumatoid ArthritisDALA R. JAROLIM, M.D.DALA R. JAROLIM, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-97-4-616_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: We have recently seen two patients with rheumatoid arthritis who were also asplenic, and read with interest the report of asplenia in patients with systemic lupus erythematosus (1). Less well documented is the association of rheumatoid arthritis and asplenia.A 57-year-old white woman presented with disseminated ophthalmic herpes zoster. The patient had a 1-year history of symmetrical small joint pain, and examination showed swelling with synovitis. Rheumatoid factor was 1:640. Serum protein electrophoresis showed a polyclonal gammopathy with normal quantitative immunoglobulins. Results of delayed hypersensitivity skin tests were normal. Peripheral smear showed Howell-Jolly bodies and thrombocytosis. A...References1. DILLONSTEINENGLISH AHR. Splenic atrophy in systemic lupus erythematosus. Ann Intern Med. 1982;96:40-3. LinkGoogle Scholar2. WARDROPDAGGLEESINGHDYETMOFFAT CJFHJA. Immunological abnormalities in splenic atrophy. Lancet. 1975;2:4-7. CrossrefMedlineGoogle Scholar3. BROWNLIEHAMERCOOKHAMWOOD BJHS. Thyrotoxicosis associated with splenic atrophy. Lancet. 1975;2:1046-7. CrossrefMedlineGoogle Scholar4. PETTITHOFFBRANDSEAHFRY JAPL. Splenic atrophy in dermatitis herpetiformis. Med J. 1972;2:438-40. CrossrefMedlineGoogle Scholar5. ASENJO C. Pteroylglutamic acid requirement of the rat and the characteristic lesion observed in the spleen of the deficient animal. J Nutr. 1948;36:601. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: DALA R. JAROLIM, M.D.Affiliations: Tulsa Medical College Tulsa, OK 74129 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySplenic involvement in rheumatic diseasesAsplenism and systemic lupus erythematosusSplenic function: physiology and splenic hypofunction 1 October 1982Volume 97, Issue 4Page: 616-617KeywordsArthralgiaHypersensitivityInflammationLupus erythematosusRheumatoid arthritisSerum proteinsSkin testsThrombocytosis ePublished: 1 December 2008 Issue Published: 1 October 1982 PDF downloadLoading ...
Primary cardiac lymphoma
Authors: C.S. Chim, A.C.L. Chan, Y.L. Kwong, R. Liang
Journal: American Journal of Hematology (1997)

Primary cardiac lymphoma is a rare entity. We report on the clinicopathological features of 2 patients with primary cardiac lymphomas: one involving the right atrium resulting in intractable right heart failure, and the other involving the pericardium with massive pericardial effusion. In the first patient, sternotomy and surgical biopsy of the tumor were performed to arrive at the diagnosis. In the second patient, CT thorax and transesophageal echocardiography helped to diagnose the pericardial tumor, and cytological examination of the pericardial fluid established the pathological diagnosis of lymphoma. Combination chemotherapy (COPP) was started in both patients. The first patient died on the first day of chemotherapy due to intractable heart failure, while the second attained a partial response to chemotherapy but died of progressive disease 8 weeks later. This is followed by a literature review of 21 patients with primary cardiac lymphoma. In conclusion, the prognosis of primary cardiac tumor remains poor. Am. J. Hematol. 54:79–83, 1997 © 1997 Wiley-Liss, Inc.
The Two-Chambered Right Ventricle
Authors: ALEXIS F. HARTMANN, ARGYRIOS A. TSIFUTIS, HAKAN ARVIDSSON, DAVID GOLDRING, Charles E. Crawford
Journal: Circulation (1962)

A relatively rare congenital cardiac malformation is described in nine patients and is characterized by aberrant hypertrophied muscular bands that divide the right ventricular cavity into two chambers. These hypertrophied muscular bands produce an effective stenosis and obstruct the outflow of blood from the right ventricle. An interventricular septal defect is usually seen in association with this abnormality. This cardiac malformation is anatomically distinct from the classic tetralogy of Fallot but may be mistakenly diagnosed as an acyanotic tetralogy of Fallot or an interventricular septal defect. The use of selective angiocardiography in conjunction with right-sided cardiac catheterization will establish the correct diagnosis. This congenital lesion is amenable to surgical correction, and five of the patients in this series were successfully operated upon with the aid of extracorporeal circulation. Surgery has been recommended for the remaining four patients because of the encouraging results.
Science-Based Views of Drug Addiction and Its Treatment
Authors: Alan I. Leshner
Journal: JAMA (1999)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Characterizing regulatory path motifs in integrated networks using perturbational data
Authors: Anagha Joshi, Thomas Van Parys, Yves Peer, Tom Michoel
Journal: Genome biology (2010)

We introduce Pathicular http://bioinformatics.psb.ugent.be/software/details/Pathicular , a Cytoscape plugin for studying the cellular response to perturbations of transcription factors by integrating perturbational expression data with transcriptional, protein-protein and phosphorylation networks. Pathicular searches for 'regulatory path motifs', short paths in the integrated physical networks which occur significantly more often than expected between transcription factors and their targets in the perturbational data. A case study in Saccharomyces cerevisiae identifies eight regulatory path motifs and demonstrates their biological significance.
Spontaneous Fistula Between a Right Common Iliac Artery and Iliac Vein
Authors: Denis Clement Astarita
Journal: JAMA (1984)

<h3>To the Editor.—</h3> As we share a particular interest in major spontaneous intra-abdominal fistulas, we enjoyed Dr Richards' case report and would like to offer our views. Since 1975, we have seen five major fistulas among 370 atherosclerotic abdominal aneurysms. Two were ileoiliac, as described by Dr Richards. Briefly, four patients underwent surgery with end-aneurysmal closure of the fistula and graft replacement of the aneurysm. Three patients had Swan-Ganz monitoring and survived. A review of 78 such cases reported in the past 30 years revealed the following: 89% survived with Swan-Ganz monitoring<i>v</i>68% without, and 84% survived with end-aneurysmal closure<i>v</i>52% with other surgical approaches. Although these observations reflect refinements in management over the years and no doubt involve many factors, the trend toward Swan-Ganz catheter monitoring and end-aneurysmorrhaphy seems to be critical. Dr Richards failed to give proper credit to Zajtchuk et al,<sup>1</sup>whose diagram clearly
Estrogen receptor β: the guardian of the endometrium
Authors: D.K. Hapangama, A.M. Kamal, J.N. Bulmer
Journal: Human Reproduction Update (2014)

BACKGROUNDThe endometrium is the primary target organ for the 'female' sex steroid hormone estrogen, which exerts effects in the endometrium via two main classical estrogen receptor (ER) isoforms, ERα and ERβ. The main function of the endometrium, embryo implantation, appears unperturbed in ERβ knockout mice, which has led researchers to disregard other potentially important functional roles that ERβ may have in endometrium. This review focuses on ERβ in the human endometrium and its protective role from the undesired effects of ERα.
Prasugrel in Clinical Practice
Authors: Deepak L Bhatt
Journal: New England Journal of Medicine (2009)

On July 10, 2009, after an 18-month review, the Food and Drug Administration (FDA) approved the thienopyridine prasugrel for use in patients with unstable angina or myocardial infarction who undergo percutaneous coronary intervention (PCI). The new drug is the latest addition to a class of agents that inhibit the platelet adenosine diphosphate (ADP) receptor, preventing initial platelet activation and consequent platelet aggregation — a mechanism that has represented a major advance in the treatment of atherothrombotic diseases.1 Indeed, the use of the thienopyridine ticlopidine in combination with aspirin to inhibit platelet aggregation facilitated the widespread use of coronary-artery stenting. Because . . .
Chemical structure and properties of selected benzene compounds in relation to biological activity.
Authors: V H Freed, R Haque
Journal: Environmental Health Perspectives (1976)

Four fundamental physical parameters of series of benzene derivatives were studied to ascertain correlations with biological activity. These included octanol/water coefficient, vapor pressure, infrared absorption (out-of-plane C-H vibration), and the pi values. Each physicochemical constant exhibited a partial correlation with biological activity suggesting that each played a role. It was presumed that more precise and specific data on the biological activity would have permitted a better correlation. It is postulated that the biological activity of a compound is due to the sum of such physicochemical factors as: partition coefficient, molecular geometry and spatial orientation, electronic characteristics of the molecular orbitals, and vibrational-rotational frequencies of constituent groups.