USE AND ABUSE OF ANTICHOLINERGIC DRUGS IN THE MANAGEMENT OF GASTROINTESTINAL DISEASE
Authors: A J CUMMINS
Journal: Annals of Internal Medicine (1957)

Article1 February 1957USE AND ABUSE OF ANTICHOLINERGIC DRUGS IN THE MANAGEMENT OF GASTROINTESTINAL DISEASEALVIN J. CUMMINS, M.D.ALVIN J. CUMMINS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-46-2-352 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Excerpt"Antispasmodic" drugs, as applied to the gastrointestinal tract, are of two varieties: (a) those depressing smooth muscle activity directly, and (b) those acting through inhibition of the parasympathetic nervous system. The first type, as exemplified by papaverine and the nitrites, has rather evanescent effects on muscle activity and, because of lack of effect on gastric secretory function, has found relatively little application in gastroenterologic therapeutics outside of acute exhibition in cases involving spasm of the biliary system. The second type of drug action can be effected either through depression of the central nervous system, blockade of peripheral ganglionic transmission or...Bibliography1. KirsnerPalmer JBWL: The problem of peptic ulcer, Am. J. Med. 13: 615, 1952. CrossrefMedlineGoogle Scholar2. RuffinBaylinLegertonTexter JMGJCWEC: Mechanism of pain in peptic ulcer, Gastroenterology 23: 252, 1953. CrossrefMedlineGoogle Scholar3. Schneider EM: Lilliput revisited, Clin. Res. Proc. 3: 153, 1955. Google Scholar4. WolfWolff SHG: Human gastric function, 1943, Oxford University Press, New York. Google Scholar5. Bockus HL: Postgraduate gastroenterology, 1950, W. B. Saunders Co., Philadelphia. Google Scholar6. Thomas JE: The external secretion of the pancreas, 1950, Charles C. Thomas, Springfield, Illinois. Google Scholar7. ShingletonAnlyanDavid WWWGAK: Treatment of experimental acute pancreatitis with Banthine, Surgery 31: 490, 1952. MedlineGoogle Scholar8. 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CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Memphis, Tennessee*Received for publication June 26, 1956.From the Department of Medicine, University of Tennessee College of Medicine, Memphis, Tennessee.Requests for reprints should be addressed to Alvin J. Cummins, M.D., Assistant Professor, Division of Medicine, The University of Tennessee, Memphis 3, Tennessee. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 February 1957Volume 46, Issue 2Page: 352-359KeywordsDrugsGastroenterology and hepatologyGastrointestinal tractMusclesNervous systemPancreatitisPeptic ulcersSmooth musclesTachycardiaUlcers ePublished: 1 December 2008 Issue Published: 1 February 1957 PDF downloadLoading ...