"PLATELET" THROMBOSIS IN LEUKEMIA
Authors: K O HUSEBYE, J M STICKNEY, W A BENNETT
Journal: Annals of Internal Medicine (1956)

Article1 May 1956"PLATELET" THROMBOSIS IN LEUKEMIAKJELD O. HUSEBYE, M.D., J. M. STICKNEY, M.D., WARREN A. BENNETT, M.D.KJELD O. HUSEBYE, M.D.Search for more papers by this author, J. M. STICKNEY, M.D.Search for more papers by this author, WARREN A. BENNETT, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-44-5-975 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptCapillary thrombosis is observed in a number of conditions. Extensive involvement has been reported in a variety of diseases, such as rickettsial infections,1 disseminated lupus erythematosus,2-4 periarteritis nodosa,5 malignancy,6 aplastic anemia7 and thrombotic thrombocytopenic purpura. The pathogenesis is as yet undetermined.Moschcowitz8was the first to report an instance of thrombotic thrombocytopenic purpura; this he did in 1925. He believed the thrombi consist of agglutinated erythrocytes, and pointed out that there is no evidence of primary vascular disease. Altschule9ascribed the lesions to damage to the vascular endothelium, with secondary deposition of platelets. Muirhead and associates10reported one case in...Bibliography1. AllenSpitz ACS: A comparative study of the pathology of scrub typhus (tsutsugamushi disease) and other rickettsial diseases, Am. J. Path. 21: 603-645, 1945. MedlineGoogle Scholar2. BaehrKlempererSchifrin GPA: A diffuse disease of the peripheral circulation (usually associated with lupus erythematosus and endocarditis), Tr. A. Am. Physicians 50: 139-152, 1935. Google Scholar3. LaszloAlvarezFeldman MHAF: The association of thrombotic thrombocytopenic purpura and disseminated lupus erythematosus: report of a case, Ann. Int. Med. 42: 1308-1320, 1955. LinkGoogle Scholar4. StickneyKeith JMNM: Renal involvement in disseminated lupus erythematosus, Arch. Int. Med. 66: 643-660, 1940. CrossrefGoogle Scholar5. KeithBaggenstoss HMAH: Primary arteritis (periarteritis nodosa) among children, J. Pediat. 18: 494-506, 1941. CrossrefGoogle Scholar6. CooperStickneyPeaseBennett TJMGLWA: Thrombotic thrombocytopenic purpura. Confirmation of clinical diagnosis of bone marrow aspiration, Am. J. Med. 13: 374-383, 1952. CrossrefMedlineGoogle Scholar7. FruminConstonMeranze AMASDR: Aplastic anemia with platelet thrombi, Blood 7: 942-947, 1952. CrossrefMedlineGoogle Scholar8. Moschcowitz E: An acute febrile pleiochromic anemia with hyaline thrombosis of the terminal arterioles and capillaries. An undescribed disease, Arch. Int. Med. 36: 89-93, 1925. CrossrefGoogle Scholar9. Altschule MD: A rare type of acute thrombocytopenic purpura: widespread formation of platelet thrombi in capillaries, New England J. Med. 227: 477-479, 1942. CrossrefGoogle Scholar10. MuirheadCrassHill EEGJM: Diffuse platelet thromboses with thrombocytopenia and hemolytic anemia (thrombotic thrombocytopenic purpura), Am. J. Clin. Path. 18: 523-532, 1948. CrossrefMedlineGoogle Scholar11. Gore I: Disseminated arteriolar and capillary platelet thrombosis: a morphologic study of its histogenesis, Am. J. Path. 26: 155-167, 1950. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Rochester, Minnesota*Received for publication November 7, 1955.From the Mayo Clinic and Mayo Foundation, Rochester, Minnesota. (The Mayo Foundation, Rochester, Minnesota, is a part of the Graduate School of the University of Minnesota.)†Abridgment of portion of thesis submitted by Dr. Husebye to the Faculty of the Graduate School of the University of Minnesota in partial fulfillment of the requirements for the degree of Master of Science in Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThrombotic Thrombocytopenic PurpuraSimilarities and Differences between the Hemolytic Uremic Syndrome and Thrombotic Thrombocytopenic PurpuraKomplikationen und supportive Therapie der Leukämien und malignen Non-Hodgkin-LymphomeDie Hämostasestörung der akuten LeukämieBIBLIOGRAPHYHerz und Kreislauf bei Erkrankungen des Blutes und der blutbildenden OrganeCrepuscular Thrombo-Embolic SyndromesThrombotic thrombocytopenic purpura 1 May 1956Volume 44, Issue 5Page: 975-984KeywordsFolic acidGraduate medical educationLesionsMetastasisPathogenesisPlateletsRocky Mountain spotted feverThrombosisThrombotic thrombocytopenic purpuraVascular diseases ePublished: 1 December 2008 Issue Published: 1 May 1956 PDF downloadLoading ...