PAINLESS MYOCARDIAL INFARCTION: A REVIEW OF THE LITERATURE AND ANALYSIS OF 220 CASES
Authors: M D ROSEMAN
Journal: Annals of Internal Medicine (1954)

Article1 July 1954PAINLESS MYOCARDIAL INFARCTION: A REVIEW OF THE LITERATURE AND ANALYSIS OF 220 CASESMELVIN D. ROSEMAN, M.D.MELVIN D. ROSEMAN, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-41-1-1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn 1768 Heberden1described very clearly and succinctly the symptoms of disease of the coronary arteries. Yet it was not until 1876 that the diagnosis of coronary thrombosis was first made by Hammer2; and this condition was not commonly considered until after Herrick3in 1912 had brought it to the attention of the clinicians. In this same article Herrick mentioned that cases with little or no pain have been described. He quoted records of his colleagues who had patients with painless coronary thrombosis. Sixteen years later Parkinson and Bedford4reëmphasized this phenomenon of coronary thrombosis without pain. They stated that...Bibliography1. Heberden W: Commentaries on the history and cause of disease, 1818, Wells & Lilly, Boston, p. 292. Google Scholar2. Major RH: Classic descriptions of disease, 1939, Charles C. Thomas, Springfield, Illinois, p. 462. Google Scholar3. Herrick JB: Clinical features of sudden obstruction of the coronary arteries, J. A. M. A. 59: 2015, 1912. CrossrefGoogle Scholar4. ParkinsonBedford JDE: Cardiac infarctions and coronary thrombosis, Lancet 1: 4, 1928. CrossrefGoogle Scholar5. Wearn JT: Thrombosis of coronary arteries, Am. J. M. Sc. 165: 250-276, 1923. CrossrefGoogle Scholar6. WilliusBrown FAGE: Coronary sclerosis; an analysis of 86 necropsies, Am. J. M. Sc. 168: 165-180, 1924. CrossrefGoogle Scholar7. EastBainCary CFCWFL: Cardiac infarction without pain, Lancet 2: 60-63, 1928. CrossrefGoogle Scholar8. Davis NS: Coronary thrombosis without pain, J. A. M. A. 98: 1806, 1932. CrossrefGoogle Scholar9. Wedd AM: Painless coronary occlusion, New York State J. Med. 28: 1091-1098, 1928. Google Scholar10. SaphirPriestHamburgerKatz OWSWWLN: Coronary arteriosclerosis, coronary thrombosis and resulting myocardial changes, Am. Heart J. 10: 762-792, 1935. CrossrefGoogle Scholar11. Stenn F: Painless coronary occlusion, Illinois M. J. 67: 381-382, 1935. Google Scholar12. BruennTurnerLevy HGKBRL: Notes on cardiac pain and coronary diseases, Am. Heart J. 11: 34-40, 1936. CrossrefGoogle Scholar13. MasterDackJaffe AMSHL: Postoperative coronary artery occlusion, J. A. M. A. 110: 1415-1418, 1938. CrossrefGoogle Scholar14. BoydWerblow LJSC: Coronary thrombosis without pain, Am. J. M. Sc. 194: 814-824, 1937. CrossrefGoogle Scholar15. GorhamMartin LWSJ: Coronary occlusion with and without pain, Arch. Int. Med. 62: 821-839, 1938. CrossrefGoogle Scholar16. StroudWagner WDJA: Silent or atypical coronary occlusion, Ann. Int. Med. 15: 25-32, 1941. LinkGoogle Scholar17. StroudWagner WDJA: Painless myocardial infarction, Pennsylvania M. J. 45: 590-593, 1942. Google Scholar18. Kennedy JA: The incidence of myocardial infarction without pain in 200 autopsied cases, Am. Heart J. 4: 703-709, 1937. CrossrefGoogle Scholar19. Babey AM: Painless acute infarction of the heart, New England J. Med. 220: 410-411, 1939. CrossrefGoogle Scholar20. PollardHarvill HMTH: Painless myocardial infarction, Am. J. M. Sc. 199: 628-635, 1940. CrossrefGoogle Scholar21. LevineRosenbaum SAFF: Prognostic value of various clinical and electrocardiographic features of acute myocardial infarction: immediate prognosis, Arch. Int. Med. 68: 913-944, 1941. CrossrefGoogle Scholar22. BaerFrankel SH: Studies in acute myocardial infarction, Ann. Int. Med. 20: 108-119, 1944. LinkGoogle Scholar23. Kugel MA: Clinical significance of pain in acute coronary occlusion with myocardial infarction, J. Mt. Sinai Hosp. 12: 422-439, 1945. Google Scholar24. FisherZukerman RLM: Coronary thrombosis, J. A. M. A. 131: 385-393, 1946. CrossrefMedlineGoogle Scholar25. Chambers WN: Acute myocardial infarction; study of 100 consecutive cases, New England J. Med. 235: 347-352, 1946. CrossrefMedlineGoogle Scholar26. MintzKatz SSLN: Recent myocardial infarction; analysis of 572 cases, Arch. Int. Med. 80: 205-236, 1947. CrossrefGoogle Scholar27. LandmanAnhaltAngrist MEHSA: Asymptomatic myocardial infarction, Arch. Int. Med. 83: 665-676, 1949. CrossrefGoogle Scholar28. BehrmanHippHeyer JHHRHE: Pain patterns in acute myocardial infarction, Am. J. Med. 9: 156-163, 1950. CrossrefMedlineGoogle Scholar29. Warner HR: "Painless" myocardial infarction, Minnesota Med. 34: 49-50, 1951. MedlineGoogle Scholar30. Rogers FB: Painless myocardial infarction, U. S. Armed Forces M. J. 4: 533-539, 1953. MedlineGoogle Scholar31. Libman E: Observations on individual sensitiveness to pain, with special reference to abdominal disorders, J. A. M. A. 102: 335-351, 1941. CrossrefGoogle Scholar32. KeeferResnik CSWH: Angina pectoris; syndrome caused by anoxemia of myocardium, Arch. Int. Med. 41: 769-807, 1928. CrossrefGoogle Scholar33. Herrick JB: Coronary artery in health and disease, Am. Heart J. 6: 589-607, 1931. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Boston, Massachusetts*Received for publication December 14, 1953.From the Fifth and Sixth Medical (Boston University) Services, Boston City Hospital, Boston, Massachusetts. Nextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byA retrospective analysis of electrocardiographic abnormalities found in black South African patients with diabetes attending a regional hospital in KwaZulu-NatalA STUDY OF CLINICAL PROFILE OF UNRECOGNISED MYOCARDIAL INFARCTIONAtypical Chest Pain in the Elderly: Prevalence, Possible Mechanisms and PrognosisCardiac MRI for Detection of Unrecognized Myocardial Infarction in Patients With End-Stage Renal Disease: Comparison With ECG and ScintigraphyStandard-EKGSilent myocardial infarctionSilent myocardial ischemia in diabetic and nondiabetic patients with coronary artery diseaseUnrecognized Myocardial InfarctionStuart E. Sheifer, MD, Teri A. Manolio, MD, PhD, and Bernard J. Gersh, MB, ChB, DPhilAn evidence-based review of the resting electrocardiogram as a screening technique for heart diseaseThe prevalence and prognostic significance of electrocardiographic abnormalitiesPrevalence, predisposing factors, and prognosis of clinically unrecognized myocardial infarction in the elderlyPlasma atrial natriuretic factor levels, impaired myocardial contractility and pain intensity in uncomplicated acute myocardial infarctionPrognosis after hospitalization for acute myocardial infarction not accompanied by typical ischemic chest painPsychosocial factors related to unrecognized acute myocardial infarctionOccult myocardial infarctionPrevalence, incidence and prognosis of recognized and unrecognized myocardial infarction in persons aged 75 years or older: The Bronx Aging StudySilent myocardial ischaemia: characteristics and managementPrävalenz der stummen MyokardischämieFrequency of painless myocardial ischemia during exercise tolerance testing in patients with and without diabetes mellitusSilent Myocardial Ischemia as a Mechanism of Sudden Cardiac DeathTreatment of Silent Myocardial Ischemia with Transdermal Nitroglycerin Added to Beta-Blockers and AlprazolamA defective angina pectoris pain warning system: Experimental findings of ischemie and electrical pain testMechanisms and therapy of silent myocardial ischemia: The effect of transdermal nitroglycerinChanging Presentation of Myocardial Infarction With Increasing Old AgeMechanisms and therapy of silent myocardial ischemia and the effect of transdermal nitroglycerinVentricular septal rupture following a clinically unrecognized myocardial infarctionMechanisms of ischemic cardiac pain and silent myocardial ischemiaIschemic cardiomyopathyAsymptomatische MyokardischämieHolter Monitor Recordings in Patients with Asymptomatic Positive Exercise Thallium-201 DefectsPain Measurement and Pain Modification by Naloxone in Patients with Asymptomatic Myocardial IschemiaPainless myocardial infarction in asthmaExperimental pain measurement in patients with asymptomatic myocardial ischemiaQuantitative comparison of extent of coronary narrowing and size of healed myocardial infarct in 33 necropsy patients with clinically recognized and in 28 with clinically unrecognized ("silent") previous acute myocardial infarctionCardiac enzymesAcute heart attacks in Leeds. The use of routinely recorded data in an epidemiological surveyApplication of Diagnostic Criteria in the Diagnosis of Myocardial InfarctionDiagnosis of acute myocardial infarction in the emergency roomPredictability of coronary heart diseaseSymptomatic myocardial infarction without chest pain: Prevalence and clinical courseThallium 201 imaging and gated cardiac blood pool scans in patients with ischemic and idiopathic congestive cardiomyopathy. A clinical and pathologic study.Unrecognised Myocardial InfarctionUnrecognized Myocardial Infarction: Five-Year Incidence, Mortality, and Risk FactorsJACK H. MEDALIE, M.D., M.P.H., U. GOLDBOURT, M.A., B.Sc.Clinical Features of Ischemic Heart DiseaseAn Aspect of the Medical-Psychiatric InterfaceDefinition und Häufigkeit des "stummen" MyokardinfarktesSubjektive und objektive Hinweiszeichen auf einen "stummen" MyokardinfarktReferencesClinical features of unrecognized myocardial infarction—Silent and symptomaticSilent Mitral Regurgitation Complicating Silent Myocardial Infarction: Hemodynamic and Morphologic DocumentationREFERENCESReferencesCharacteristics and Significance of Prodromes of Coronary Care Unit PatientsFactors contributing to delay in responding to the signs and symptoms of acute myocardial infarctionCase 50-1968Clinical presentation of myocardial infarction in the elderly.Coronary Heart Disease in Chronic Schizophrenic Patients�ber den MyokardinfarktRECOGNITION OF ACUTE MYOCARDIAL INFARCTION IN THE DETERIORATED ELDERLY PSYCHOTIC PATIENTDie Grundstoffe der NahrungSTEROIDS AND ECZEMACOLD-FOOT SYNDROMEDie Coronarerkrankungen. Coronarinsuffizienz, Angina pectoris und HerzinfarktAcute myocardial infarction in a city hospitalPHEOCHROMOCYTOMA ASSOCIATED WITH PAINLESS MYOCARDIAL INFARCTION*MARTIN H. BOLDT, M.D., F.A.C.P., MORRIS FLEXNER, M.D., F.A.C.P., ALVIN B. ORTNER, M.D., F.A.C.S.Clinical and Anatomic Features in Five Hundred Patients with Fatal Acute Myocardial InfarctionA CLINICO-PATHOLOGICAL STUDY OF CORONARY DISEASEPAINLESS CARDIAC INFARCTIONPostoperative Myocardial InfarctionPAINLESS MYOCARDIAL INFARCTIONSELF-INDUCED EPILEPSY 1 July 1954Volume 41, Issue 1Page: 1-8KeywordsCoronary arteriesMyocardial infarctionStable coronary artery diseaseThrombosis ePublished: 1 December 2008 Issue Published: 1 July 1954 Copyright & PermissionsCopyright, 1954, by The American College of PhysiciansPDF downloadLoading ...