tbuckley/cabot-search huggingface dataset:
Infection Caused by<i>Francisella philomiragia</i>(Formerly<i>Yersinia philomiragia</i>)
Authors: Jay D. Wenger
Journal: Annals of Internal Medicine (1989)

We evaluated the clinical characteristics of patients with Francisella philomiragia (formerly Yersinia philomiragia) isolated from normally sterile sites. Isolates from 14 patients were received by the Centers for Disease Control between 1975 and 1987: 9 were from blood; 2 from lung biopsies; and 1 each from pleural, peritoneal, and cerebrospinal fluid. Underlying problems included chronic granulomatous disease in 5 patients, near-drowning in 5, and a myeloproliferative disease in 2. All 13 patients for whom records were available had a febrile syndrome compatible with bacterial infection. Pneumonia and fever-bacteremia were the commonest clinical syndromes reported. In 7 cases, F. philomiragia was the only sterile-site isolate, and the clinical syndrome did not resolve without appropriate antibiotics. Familiarity with this organism is important because of its ability to cause serious disease in chronic granulomatous disease and near-drowning patients. Further study may yield new insights into pathogenic and host defense mechanisms.
Doctor migration 1962-4. With an Addendum for 1964-5 from the Ministry of Health.
Authors: R. Ash, H. D. Mitchell
Journal: BMJ (1968)

This paper gives estimates of the numbers of provisionally or fully registered doctors entering or leaving Great Britain during the two years ended 30 September 1964 and explains methods whereby information about such movement can be regularly obtained in future.The methods used (which aim essentially at determining whether a doctor is or is not in Great Britain on a particular date) ensure, in general, that doctors entering or leaving Great Britain on short holidays, visits, etc., are excluded, but do not call for inquiries about doctors' intentions and so cannot separately identify those whose changes of residence are likely to be permanent.However, the figures suggest that considerable numbers of British-born doctors who leave do in fact return after some experience abroad.
STEEOLS AND KEKATINIZATION*
Authors: H. J. YARDLEY
Journal: British Journal of Dermatology (1969)

Journal Article STEEOLS AND KEKATINIZATION Get access H. J. YARDLEY H. J. YARDLEY Medical Research Council, Unit for Research on the Experimental Pathology of the Skin, The Medical School, University, Birmingham 15, England Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 81, Issue s2, 1 March 1969, Pages 29–38, https://doi.org/10.1111/j.1365-2133.1969.tb12843.x Published: 01 March 1969
Cost of Tests
Authors: PAUL D. SAVILLE
Journal: Annals of Internal Medicine (1971)

Letters, Comments, and Corrections1 December 1971Cost of TestsPAUL D. SAVILLE, M.D., F.A.C.P.PAUL D. SAVILLE, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-75-6-968_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: In their article "Use of the Laboratory in a Teaching Hospital" (Ann Intern Med75:157-163, 1971) Griner and Liptzin stress the tendency for housestaffs to order a large, perhaps excessive, number of laboratory tests. They point out that the charges for these tests average $459, or approximately one quarter of the hospital bill. The chief thrust of this article is that by ordering more tests than "necessary," housestaffs are contributing to the run-away cost of hospital medical care. Nothing could be further from the truth. We must not confuse costs with charges. The increase in costs of...References1. GELLMAN D: The price of progress: technology and the cost of medical care. Can Med Assoc J 104:401-406, 1971 MedlineGoogle Scholar2. Editorial. The price of "progress." Ibid., p. 417 Google Scholar3. GELLMAN D: The role of voluntary prepayment in a changing environment, in Proceedings of 3rd International Conference, International Federation of Voluntary Health Service Funds. Chicago, 1970, pp. 22-29 Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Section of Rheumatology School of Medicine Creighton University Omaha, Nebr. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 December 1971Volume 75, Issue 6Page: 968-970KeywordsLaboratory testsResearch laboratories Issue Published: 1 December 1971 PDF DownloadLoading ...
Personality Traits That Can Affect Adaptation after Colectomy
Authors: Robert Weinryb, Robert Rössel
Journal: Psychotherapy and Psychosomatics (1986)

The purpose of the present study was to examine how specific personality traits and/or conflicts could serve to predict nonadaptability after surgical treatment for ulcerative colitis. In order to define the scope of the study and to establish more specific hypotheses, retrospective studies were conducted by in depth interviews with 10 patients. Five of the patients had undergone colectomy with proctomucosectomy and ileal pouch ad modum Parks, and 5 had had a proctocolectomy with ileostomy ad modum Brooke. The interviews were recorded on tape and analyzed by the interviewer as well as by an independent evaluator. In addition, the operating surgeon provided an independent evaluation of the patients' postoperative adaptation. There was good consensus between both sets of assessments based on interviews as well as between the interview diagnoses and the surgeon's evaluation. There was no observed correlation between prevailing psychiatric diagnostic categories and postoperative adaptation. Psychological factors, such as a discrepancy between body image and body ideal, alexithymic characteristics, abnormal aggression patterns, extensive physical exercise and muscular training, showed varying degrees of negative correlation with postoperative adaptation.
Users' Guides to the Medical Literature
Authors: Adrienne G. Randolph, R. Brian Haynes, Jeremy C. Wyatt, Deborah J. Cook, Gordon H. Guyatt
Journal: JAMA (1999)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Retrieval of Medical Literature
Authors: Pamela M. Elwell
Journal: JAMA (1986)

<h3>To the Editor.—</h3> The article and editorial about MEDIS, the full-text medical literature retrieval system offered by Mead Data, describe an elegant system for accessing medical literature.<sup>1,2</sup>However, they have not addressed all of the questions concerned with searching this data base. Each of us has been searching on-line for a number of years. Recently, we both attended a demonstration of the MEDIS system in conjunction with a MEDLINE update in Dayton, Ohio. Although favorably impressed by the searching features available with this system, the limited number of journals included in the system seemed to be a detrimental factor. Noticeably missing are such significant journals such as<i>British Medical Journal, New England Journal of Medicine, and Journal of Bone and Joint Surgery</i>. Also, some general categories such as radiology, anesthesiology, and gastroenterology are not represented in the library of journals offered in full text. The entire data base simply
US passes bill protecting low income nursing home patients
Authors: F. Charatan
Journal: BMJ (1999)

Earlier this month, the US House of Representatives passed a bill which bars nursing homes from evicting Medicaid patients, who are generally less profitable for the homes than those who pay privately.

The bill was sponsored by representative Jim Davis of Florida and cosponsored by 60 members of Congress, including almost the entire delegation from Florida. The bill does not force nursing homes to remain in Medicaid, and they may …
FIBROMA OF THE NASOPHARYNX.TRACHEOTOMY, EXTERNAL CAROTID LIGATION, EXTIRPATION, CURE.
Authors: CHEVALIER JACKSON
Journal: JAMA (1906)

<h3>History.</h3> —S. D., male, aged 14, gave a history of an increasing nasal stenosis of a few years' duration. Several pieces of a "polyp" had been removed by physicians at different times, followed in each instance by severe hemorrhage, but with no relief to the breathing, which grew worse until scarcely enough air to sustain life could be inspired, even with the mouth widely open. His parents feared he would choke to death at night, and he was awakened by a choking sensation every time he fell asleep. Death from inanition threatened because of increasing dysphagia. Bleeding had been frequent, and a week before admission a severe hemorrhage from the nose and throat almost exsanguinated the boy. Headache and earache were frequent and severe. <h3>Examination.</h3> —The boy was frail, emaciated, pale and anemic. Leucocytes were increased; hemoglobin was decreased. Nasal respiration was impossible; his mouth was never closed except to
Occupational Exposure to Heat or Noise and Reduced Fertility-Reply
Authors: Marcus B. Bond
Journal: JAMA (1985)

<h3>In Reply.—</h3> Adverse effects of testicular hyperthermia are well known and were described in the COUNCIL REPORT as well as in my reply to Dr Levine's letter.<sup>1</sup>Such effects from occupational exposure to heat are not established. The article by Rachootin and Olsen was published after our article on physical forces was submitted. Had we known of this article, it would have been referenced, although the information in it is not sufficient to change the implications (not conclusions) that occupational exposures to heat are not likely to have significant adverse effects on male reproductive functions. The article by Rachootin and Olsen did not define "heat exposures," and the authors properly did not draw any conclusions about effects of occupational exposures to heat in males. As to the possibility of adverse effects on human female fertility, the same article reported an association between women with fertility problems and exposure to
Coronary thrombolysis with recombinant single-chain urokinase-type plasminogen activator in patients with acute myocardial infarction.
Authors: F Van de Werf, J Vanhaecke, H de Geest, M Verstraete, D Collen
Journal: Circulation (1986)

Seventeen patients with acute transmural myocardial infarction and angiographically confirmed complete coronary occlusion were treated with heparin combined with intravenous single-chain urokinase-type plasminogen activator (scu-PA), obtained by expression of the cDNA encoding mature human scu-PA in Escherichia coli. In eight patients, recombinant scu-PA (rscu-PA) was given as a 10 mg bolus followed by 30 mg over 1 hr. Recanalization was obtained in six patients, but with persistent delayed opacification of the vessel in four of these patients. During infusion, a plateau level of rscu-PA antigen in plasma of 3.4 micrograms/ml (median value, range 1.4 to 5.5) was reached. At the end of the infusion the alpha 2-antiplasmin level had decreased to 54% (median, range 22% to 82%) of the preinfusion level, the fibrinogen level to 89% (median, range 26% to 101%), and fibrinogen degradation products (FDPs) to 20 micrograms/ml (median, range 8 to 387). In nine patients, rscu-PA was administered as a 10 mg bolus followed by 60 mg over 1 hr. This resulted in recanalization with normal distal filling of the vessel in seven patients, within 46 +/- 17 min (mean +/- SD). During infusion the concentration of rscu-PA in plasma increased to a median value of 7.4 micrograms/ml (range 4.0 to 13.3). At the end of the infusion the alpha 2-antiplasmin level was 22% of baseline (range 5% to 47%), the fibrinogen level 45% (range 4% to 94%), and the concentration of FDPs 87 micrograms/ml (range 6 to 1034). No significant bleeding or short-term side effects were observed.(ABSTRACT TRUNCATED AT 250 WORDS)
Estimated numbers of homeless and homeless mentally ill people in north east Westminster by using capture-recapture analysis
Authors: N Fisher, S W Turner, R Pugh, C Taylor
Journal: BMJ (1994)

<h3>Abstract</h3> <b>Objectives</b>: To use routinely collected data to provide a reliable estimate of the size and psychiatric morbidity of the homeless population of a given geographical area by using capture-recapture analysis. <b>Design</b>: A multiple sample, log-linear capture-recapture method was applied to a defined area of central London during 6 months. The method calculates the total homeless population from the sum of the population actually observed and an estimate of the unobserved population. Data were collected from local agencies used by homeless people. <b>Subjects</b>: Homeless people in north east West-minster residing in bed and breakfast accommodation and hostels or sleeping rough who had contacted statutory or voluntary agencies in the area. <b>Results</b>: 2150 contacts by 1640 homeless people were recorded. The estimated unobserved population was 3293, giving a total homeless population for the period of around 5000 (SD 1250). Mental health problems were significantly less prominent in the unobserved compared with the observed population (23% (754) v 40% (627), P&lt;0.0001). For both groups the prevalence varied greatly with age and sex. <b>Conclusions</b>: Capture-recapture techniques can overcome problems of ascertainment in estimating populations of homeless and homeless mentally ill people. Prevalences of mental illness derived from surveys that do not correct for ascertainment are likely to be falsely inflated while at the same time underestimating the total size of the homeless mentally ill population. Population estimates derived from capture-recapture techniques may usefully provide a good basis for including homeless populations in capitation calculations for allocating funds within health services.
Ultrasound in the Diagnosis of Rectus Sheath Hematoma
Authors: George M. Wyatt
Journal: JAMA (1979)

RECTUS sheath hematoma, an uncommon lesion, confronts the clinician with a diagnostic problem. Although it can sometimes be recognized in an appropriate clinical setting, the entity may be mistaken for an acute intra-abdominal condition and lead to an unnecessary emergency surgical procedure. Three recent cases are briefly presented, with a discussion of the cause, clinical signs and symptoms, and current methods of diagnosis. <h3>Report of Cases</h3><h3>Case 1.—</h3> This 67-year-old woman was admitted from a nursing home because of abdominal pain and distension. The surgeon felt a tender mass in the right midabdomen and made a clinical diagnosis of hydrops of the gallbladder; surgery was performed. A right rectus sheath hematoma was found and drained. Exploration of the abdominal cavity was normal. A sonogram performed the following day showed a left rectus sheath hematoma (Fig 1). The postoperative period was complicated by staphylococcal sepsis, congestive heart failure, and renal failure.
Sjogren's Disease and Rheumatoid Arthritis
Authors: S. R. Reader, H. M. Whyte, P. C. Elmes
Journal: Annals of the Rheumatic Diseases (1951)

Report of One Case Clinical Observations.-Thepatient (R.I.No. 18667/43) was a married woman who was first admitted to the Radcliffe Infirmary in July, 1948, at the age of 28.Her presenting symptoms were pain and stiffness of the joints for 3 months.The condition had started in her right knee and had spread to the left knee, shoulders, elbows, wrists, and fingers.289
Single-agent arsenic trioxide in the treatment of children with newly diagnosed acute promyelocytic leukemia
Authors: Jin Zhou, Yingmei Zhang, Jinmei Li, Xiaoxia Li, Jinxiao Hou, Yanqiu Zhao, Xiuhua Liu, Xueying Han, Longhu Hu, Shuye Wang, Yanhong Zhao, Ying Zhang, Shengjin Fan, Chengfang Lv, Limin Li, Lingling Zhu
Journal: Blood (2009)
Hepatitis B Immune Serum Globulin in Prevention of Nonparenterally Transmitted Hepatitis B
Authors: Wolf Szmuness, Alfred M. Prince, Morris Goodman, Carlos Ehrich, Rubin Pick, Manzoor Ansari
Journal: New England Journal of Medicine (1974)

To compare the protective effects of hepatitis B immune globulin and standard immune globulin, 44 randomly selected children admitted to three institutions received hepatitis immune globulin, and 37 others received standard globulin at four-month intervals. Fifty-two untreated children admitted to one of the institutions were also observed. In those given hepatitis immune globulin, specific antibody remained detectable up to four months. During a follow-up period of 1 1/2 to two years, anicteric or inapparent hepatitis B developed in 11 per cent of children receiving either type of globulin; none remained persistently antigen positive. In 25 per cent of the untreated children serologic or biochemical evidence of hepatitis B infection developed, and in half of these a persistent antigen carrier state developed. Thus, standard immune globulin and hepatitis B immune globulin may be effective in preventing or modifying nonparenterally transmitted hepatitis B in an endemic setting. (N Engl J Med 290:701–706, 1974)
Identification of alpha 1-adrenergic receptors in cultured rat myocardial cells with a new iodinated alpha 1-adrenergic antagonist, [125I]IBE 2254.
Authors: L E Kupfer, R B Robinson, J P Bilezikian
Journal: Circulation Research (1982)

The presence of a-adrenergic receptors in purified cultures of neonatal rat ventricular muscle cells first was confirmed pharmacologically and then demonstrated directly with a new iodinated ai-selective radioligand [ 125 I]-I-2-[/6-(4-hydroxyphenyl)ethylaminomethyI]tetralone ([ I25 I] IBE 2254).These cells respond to the a-adrenergic agonist phenylephrine with a positive chronotropic response that is markedly inhibited by the ai-selective antagonist, prazosin.The radioligand [' 5 I] IBE 2254 binds to suspensions of intact cells rapidly (15 minutes), reversibly and with high specificity (80-85% inhibited by excess unlabeled BE 2254).As identified by [ 125 I]IBE 2254, cardiac cells contain a homogeneous class of binding sites of high affinity (K D = 324 ± 42 pin) and limited capacity (33,000 ± 4,000 sites/cell).Binding is stereoselective, as determined by the greater potency of I-than d-norepinephrine in competing for specific binding sites.Adrenergic antagonists compete with [ 125 I] IBE 2254 in the order expected for binding to an ai-receptor (prazosin = BE 2254 > phentolamine > yohimbine).Therefore, the high specific binding observed with [ 125 I]IBE 2254, together with the inherently high specific activity of iodinated radioligands, suggest that [ 125 I|IBE 2254 will be a useful probe for the ai-adrenergic receptor in a variety of cell systems.
License in Germany; American and European Medical Colleges.
Authors: G. A. Blech
Journal: JAMA (1898)

Chicago, Ill., Jan. 10, 1898. <h3>To the Editor:</h3> —I am again forced to reply to Dr. Becker of Toledo, and this time on a different subject. I must therefore apologize for using two headings for this communication. As far as the laws regulating the practice of medicine in Germany are concerned, I am done and shall waste no more time with them. But Dr. Becker accuses me of underrating the value of American medical colleges, particularly of Johns Hopkins or Harvard. Now any careful reader, familiar with the most rudimentary principles of English composition, will see that I<i>never expressed my opinion</i>, but that I was stating what<i>legal</i>value the diplomas of an American medical school has before the German licensing board in Germany. <i>My</i>opinion puts Johns Hopkins and Harvard even above the average German university. To me Osier is second to none, and Kelly far outshines, as
What is an open label trial?
Authors: P. Sedgwick
Journal: BMJ (2014)

Researchers assessed the effectiveness of prazosin combined with scorpion antivenom in assisting recovery from scorpion sting. An open label randomised controlled trial study design was used. The control treatment was prazosin alone. The setting was a hospital and research centre in Mahad, a region of India. Participants were patients with grade 2 scorpion envenomation, older than 6 months, and with no cardiorespiratory or central nervous system abnormalities. In total, 70 patients were recruited and allocated to treatment (35 to prazosin and scorpion antivenom, and 35 to prazosin alone) by block randomisation.1 The primary endpoint was resolution of the clinical syndrome within 10 hours of treatment, as assessed by the researchers. The secondary endpoints included the time needed for complete resolution of the clinical syndrome. The proportion of patients who showed complete resolution of the clinical syndrome within 10 hours of treatment was significantly greater in the prazosin plus antivenom group than in the prazosin alone group (91.4% v 22.9%; difference 68.5%, 95% confidence interval 51.8% to 85.2%; P<0.001). The mean time needed for complete resolution of the clinical syndrome was significantly shorter in the antivenom plus prazosin group (8 v 17.7 h; difference −9.7 h, −6.9 to −12.4); P<0.001). The researchers concluded that recovery from a scorpion sting was hastened by simultaneous administration of scorpion antivenom plus prazosin compared with prazosin alone. Which of the following statements, if any, are true?
Expanding antiretroviral therapy in Malawi: drawing on the country's experience with tuberculosis
Authors: Anthony D Harries, Edwin Libamba, Erik J Schouten, Andrina Mwansambo, Felix M Salaniponi, Rex Mpazanje
Journal: BMJ (2004)

<i>The DOTS ("directly observed treatment, short course") strategy has been successfully used in developing countries to provide effective control of tuberculosis. Field workers in Malawi are promoting the same approach for HIV infection through the expansion of highly active antiretroviral therapy</i>