CULTURE OF HUMAN MARROW; STUDIES OF THE EFFECTS OF ROENTGEN-RAYS
Authors: Edwin E. Osgood, George J. Bracher
Journal: Annals of Internal Medicine (1939)

Article1 October 1939CULTURE OF HUMAN MARROW; STUDIES OF THE EFFECTS OF ROENTGEN-RAYSEDWIN E. OSGOOD, M.D., GEORGE J. BRACHER, M.D.EDWIN E. OSGOOD, M.D.Search for more papers by this author, GEORGE J. BRACHER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-13-4-563 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe monographs on the biologic action of roentgen-rays by Duggar1 and Scott2 and on the effects of roentgen-rays on the blood and blood-forming organs by Selling and Osgood3 should be consulted for a review of the literature.Most of the research on the action of roentgen-rays has been done on insect eggs, lower animals or plants and those studies which have been made on human material have necessarily not been quantitative nor adequately controlled. Much of this research has been done with doses far above any that are ever used in clinical therapy. Scott, therefore, very logically states:(1) When...References1. DUGGAR BM: Biological effects of radiation: mechanisms and measurement of radiation, applications in biology, photochemical reactions, effects of radiant energy on organisms and organic products, Vols. I and II, 1936, McGraw-Hill Book Co., New York. CrossrefGoogle Scholar2. SCOTT CM: Some quantitative aspects of the biological action of X and γ rays, His Majesty's Stationery Office, London, 1937. Google Scholar3. SELLINGOSGOOD LEE: Action of benzol, roentgen rays, and radioactive substances on the blood and blood-forming tissues, Downey's Handbook of Hematology, 1938, iv, Pp. 2691-2801, Paul B. Hoeber, Inc., New York. Google Scholar4. OSGOODBROWNLEE EEIE: Culture of human marrow: details of a simple method, Jr. Am. Med. Assoc., 1937, xviii, 1793. CrossrefGoogle Scholar5. YOUNGOSGOOD RHEE: Sternal marrow aspirated during life: cytology in health and in disease, Arch. Int. Med., 1935, lv, 186. OSGOOD, E. E., and ASHWORTH, CLARICE M.: Atlas of hematology, 1937, pp. 205-206, J. W. Stacey, Inc., San Francisco. CrossrefGoogle Scholar6. OSGOOD EE: Culture of human marrow: length of life of the neutrophils, eosinophils and basophils of normal blood as determined by comparative cultures of blood and sternal marrow from healthy persons, Jr. Am. Med. Assoc., 1937, cix, 933. CrossrefGoogle Scholar7. OSGOOD EE: The histogenesis, classification and identification of the cells of the blood and marrow based on cultures and hematologic studies of human marrow and blood, Am. Jr. Clin. Path., 1938, viii, 59. OSGOOD, E. E., and ASHWORTH, CLARICE M.: Atlas of hematology, 1937, pp. 28-29, J. W. Stacey, Inc., San Francisco. CrossrefGoogle Scholar8. BRUESJACKSON AMEB: Nuclear abnormalities resulting from inhibition of mitosis by colchicine and other substances, Am. Jr. Cancer, 1937, xxx, 504. CrossrefGoogle Scholar9. JONES OP: Origin of neutrophils in pernicious anemia (Cooke's macropolycytes): biopsies of bone marrow, Arch. Int. Med., 1937, lx, 1002. CrossrefGoogle Scholar10. ISAACS R: Maturing effect of roentgen rays on blood-forming cells, Arch. Int. Med., 1932, l, 836. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Portland, Oregon*Read at the New Orleans meeting of the American College of Physicians, March 27, 1939 and at the Chicago meeting of the American Roentgen-Ray Society, Sept. 22, 1939.From the Division of Experimental Medicine and the Department of Roentgenology, University of Oregon Medical School, Portland, Ore.This work was made possible by a grant from J. Guy Strohm, M.D., Head of the Division of Urology, University of Oregon Medical School.With the technical assistance of Evelyn A. Packham. Nextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byTissue Culture in RadiobiologyRADIOBIOLOGIC OBSERVATIONS ON HUMAN HEMIC CELLS IN VIVO AND IN VITRO*The Effect of Ionizing Radiations and Tumour-Chemotherapeutic Agents on the Bone MarrowDemecolcine toxicityHistopathological effects of immediate and delayed radiation death in hamsters produced by two million volt x-rays I. The lymphocytic organs: Spleen, lymph nodes, thymus and bone marrow 1 October 1939Volume 13, Issue 4Page: 563-575KeywordsBiologicsBloodBone marrowHealth services researchUrology ePublished: 1 December 2008 Issue Published: 1 October 1939 Copyright & PermissionsCopyright, 1939, by The American College of PhysiciansPDF downloadLoading ...