DISCOID LUPUS ERYTHEMATOSUS: AN ANALYSIS OF ITS SYSTEMIC MANIFESTATIONS
Authors: E L DUBOIS, S MARTEL
Journal: Annals of Internal Medicine (1956)

Article1 March 1956DISCOID LUPUS ERYTHEMATOSUS: AN ANALYSIS OF ITS SYSTEMIC MANIFESTATIONSEDMUND L. DUBOIS, M.D., STUART MARTEL, M.D.EDMUND L. DUBOIS, M.D., STUART MARTEL, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-44-3-482 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlthough it is generally accepted that the various forms of lupus erythematosus are merely different manifestations of the same disease, the most common variety; namely, the chronic discoid form, has been regarded as primarily a localized manifestation whose systemic changes are either absent or missed. The object of this study is to point out that these generalized changes are very common in discoid lupus and have hitherto been overlooked.Chronic discoid lupus is characterized by skin lesions which in the active phase consist of erythematous plaques of varying sizes with scaling, follicular plugging, followed in the healing stages by atrophy...Bibliography1. Kierland RR: Classification and cutaneous manifestations of lupus erythematosus, Proc. Staff Meet., Mayo Clin. 15: 675, 1940. Google Scholar2. GoldGowing SCNF: Systemic lupus erythematosus, Quart. J. Med. 88: 457, 1953. Google Scholar3. Brunsting LA: Acute disseminated lupus erythematosus, M. Clin. North America 35: 399, 1951. CrossrefMedlineGoogle Scholar4. Keil H: Conception of lupus erythematosus and its morphologic variants, Arch. Dermat. and Syph. 36: 729, 1937. CrossrefGoogle Scholar5. WilsonJordan APJW: Relationship of chronic discoid and disseminated lupus erythematosus, New York State J. Med. 50: 2449, 1950. 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Author, Article, and Disclosure InformationAffiliations: *Received for publication August 13, 1955.From the Departments of Internal Medicine and Dermatology, University of Southern California Medical School, and the Los Angeles County Hospital, Los Angeles, California. 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