Fallacies and Dangers in the Treatment of Exophthalmic Goiter by Iodine
Authors: Willard Owen Thompson, Phebe K. Thompson
Journal: Annals of Internal Medicine (1932)

Article1 March 1932Fallacies and Dangers in the Treatment of Exophthalmic Goiter by IodineWILLARD OWEN THOMPSON, M.D., F.A.C.P., PHEBE K. THOMPSON, M.D.WILLARD OWEN THOMPSON, M.D., F.A.C.P.Search for more papers by this author, PHEBE K. THOMPSON, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-5-9-1129 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptUntil about ten years ago, the treatment of exophthalmic goiter by iodine was considered a dangerous procedure, although it was not claimed that its immediate effects were always harmful. The attitude then prevalent is fairly well expressed in the statement of T. Kocher1"Es ist ein zweischneidigen Schwert und der Schaden überwiegt" (it is a two-edged sword and harm predominates). Following the demonstration of the clinical improvement and the reduction in basal metabolism during its administration to patients with toxic goiter2, the pendulum swung almost completely to the other extreme. The consequence has been that most beneficial results that occur...References1 KOCHER T: Über Jodbasedow, Verhandl. d. deutsch. Gesellsch. f. Chir., 1910, xxxix, 396. Google Scholar2 PLUMMER HS: Results of administering iodine to patients having exophthalmic goiter, Jr. Am. Med. Assoc., (Soc. Proceedings), 1923, lxxx, 1955. PLUMMER, H. S., and BOOTHBY, W. M.: The value of iodine in exophthalmic goiter, Jr. Iowa Med. Soc., 1924, xiv, 66-73. NEISSER, E.: Über Jodbehandlung bei Thyreotoxikose, Berl. klin. Wchnschr., 1920, lvii, 461-463. LOEWY, A., and ZONDEK, H.: Morbus Basedowii und Jodtherapie, Deutsch. med. Wchnschr., 1921, xlvii, 1387-1389. Google Scholar3 CROTTI A: Thyroid and thymus, 1918, Lea and Febiger, Philadelphia and New York, p. 411. 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(Jackson states that he has been able to produce improvement in some of these patients by administering enormous doses of iodine. Experience we have had in determining the range of effective iodine dosage in exophthalmic goiter does not seem to support his contention.) CrossrefGoogle Scholar37 PEMBERTON Jd: Goiter; management of the poor surgical risk, Arch. Surg., 1930, xx, 591-606. CrossrefGoogle Scholar38 LAHEY FH: The use of iodine in goiter, Bost. Med. and Surg. Jr., 1925, cxciii, 487-490. CrossrefGoogle Scholar39 LAHEY FH: The management of goiter, Jr. Ind. State Med. Assoc., 1930, xxiii, 117-122. Google Scholar40 CLUTE HM: Effect of compound solution of iodine and rest in surgery of exophthalmic goiter, Jr. Am. Med. Assoc., 1926, lxxxvi, 105-109. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Chicago, Ill.*Received for publication, September 3, 1931.†From the Department of Medicine, Rush Medical College and the Presbyterian Hospital, Chicago, Ill. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 March 1932Volume 5, Issue 9Page: 1129-1137KeywordsHospital medicine Issue Published: 1 March 1932 PDF downloadLoading ...