EVALUATION OF THREE DIAGNOSTIC PROCEDURES FOR SYSTEMIC LUPUS ERYTHEMATOSUS
Authors: J R HASERICK
Journal: Annals of Internal Medicine (1956)

Article1 March 1956EVALUATION OF THREE DIAGNOSTIC PROCEDURES FOR SYSTEMIC LUPUS ERYTHEMATOSUSJOHN R. HASERICK, M.D., F.A.C.P.JOHN R. HASERICK, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-44-3-497 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptDemonstration of the cellular aggregation which constitutes the lupus erythematosus (LE) phenomenon in heparinized bone marrow1 was the basis of the first in a series of specific diagnostic procedures in systemic lupus erythematosus (SLE).2 When this phenomenon was also demonstrated in heparinized3 and in clotted4 peripheral blood of patients suffering from this disease, such preparations were also used in laboratory diagnosis. Finally, the reproduction in vitro of the LE phenomenon by adding LE plasma or serum to cells of normal bone marrow5, 6 added another in this series of tests.Thus, the three types of diagnostic procedures used have in...Bibliography1. HargravesRichmondMorton MMHR: Presentation of two bone marrow elements; "tart" cell and the "L.E." cell, Proc. Staff Meet., Mayo Clin. 23: 25, 1948. MedlineGoogle Scholar2. HaserickSundberg JRRD: The bone marrow as a diagnostic aid in acute disseminated lupus erythematosus, J. Invest. Dermat. 11: 209, 1948. CrossrefMedlineGoogle Scholar3. SundbergLick RDNB (a) : "L.E." cells in the blood in acute disseminated lupus erythematosus, J. Invest. Dermat. 12: 83, 1949. (b) Moffatt, T. W., Barnes, S., and Weiss, R. S.: The induction of the L.E. cell (Hargraves) in normal peripheral blood, J. Invest. Dermat. 14: 100-153, 1950. CrossrefMedlineGoogle Scholar4. BarnesMoffattWeiss STWRS (a) : Demonstration of the L.E. cell in the absence of anti-coagulant, J. Invest. Dermat. 14: 397, 1950. (b) Gonyea, L. M., Kallsen, R. A., and Marlow, A. A.: The occurrence of the "L.E." cell in clotted blood, J. Invest. Dermat. 15: 11, 1950. CrossrefMedlineGoogle Scholar5. HaserickBortz JRDW: Normal bone marrow inclusion phenomenon induced by lupus erythematosus plasma, J. Invest. Dermat. 13: 47, 1949. CrossrefMedlineGoogle Scholar6. Hargraves MM: Production in vitro of the L.E. cell phenomenon; use of normal bone marrow elements and blood plasma from patients with acute disseminated lupus erythematosus, Proc. Staff Meet., Mayo Clin. 24: 234, 1949. MedlineGoogle Scholar7. Haserick JR: Blood factor in lupus erythematosus, Chapter V in MacKenna, R. M. B. (editor): Modern trends in dermatology, Second Series, 1954, Paul B. Hoeber, Inc., New York, pp. 76-86. Google Scholar8. Haserick JR: Modern concepts of lupus erythematosus; a review of 126 cases, J. Chronic Dis. 1: 317, 1955. CrossrefMedlineGoogle Scholar9. JessarLamont-HaversRagan RARWC: Natural history of lupus erythematosus disseminatus, Ann. Int. Med. 38: 717, 1953. LinkGoogle Scholar10. HaserickBortz JRDW: A new diagnostic test for acute disseminated lupus erythematosus, Cleveland Clin. Quart. 16: 158, 1949. CrossrefGoogle Scholar11. HaserickLewisBortz JRLADW (a) : Blood factor in acute disseminated lupus erythematosus. I. Determination of gamma globulin as specific plasma fraction, Am. J. M. Sc. 219: 660-663, 1950. (b)Haserick, J. R., and Lewis, L. A.: Blood factor in acute disseminated lupus erythematosus. II. Induction of specific antibodies against L.E. factor, Blood 5: 718, 1950. CrossrefMedlineGoogle Scholar12. Conley L: Personal communication to author. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Cleveland, Ohio*Presented at the Annual Session of the American College of Physicians, Philadelphia, Pennsylvania, April 28, 1955. Received for publication Nov. 7, 1955.From The Cleveland Clinic Foundation and The Frank E. Bunts Educational Institute.†In collaboration with Miss Mary Stepien, Laboratory Technician, Cleveland Clinic. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byUntersuchungen über die Leistungsfähigkeit dreier verschiedener Methoden zum Nachweis antinucleärer Faktoren: des direkten LE-Zellen-Tests, des Loose body-Tests und des Antihumanglobulin-KonsumptionstestsEvaluation of the Hyland L.E.-TestEvaluation of the Hyland L.E.-TestImmunologic manifestations of a group of patients with a diagnosis of discoid lupus erythematosusImmunoleukopenie und -agranulozytoseRHEUMATISM AND ARTHRITIS: REVIEW OF AMERICAN AND ENGLISH LITERATURE OF RECENT YEARS (THIRTEENTH RHEUMATISM REVIEW)*CHARLEY J. SMYTH, M.D., F.A.C.P., ROGER L. BLACK, M.D., FELIX E. DEMARTINI, M.D., IVAN F. DUFF, M.D., F.A.C.P., EPHRAIM P. ENGLEMAN, M.D., F.A.C.P., DONALD C. GRAHAM, M.D., F.R.C.P.(C), MAX M. MONTGOMERY, M.D., F.A.C.P., HOWARD F. POLLEY, M.D., F.A.C.P., EDWARD F. ROSENBERG, M.D., F.A.C.P., CARLOS F. SACASA, M.D., F.A.C.P., OTTO STEINBROCKER, M.D., HANS WAINE, M.D., GEORGE M. WILSON JR., M.D.The L. E. phenomenon and systemic lupus erythematosusPLEURITIS IN SYSTEMIC LUPUS ERYTHEMATOSUS: ITS IMPORTANCE AS AN EARLY MANIFESTATION IN DIAGNOSIS*WILLIAM A. WINSLOW, M.D., LESTER N. PLOSS, M.D., BERNARD LOITMAN, M.D.The incidence of the L.E. cell phenomenon in patients with rheumatoid arthritis. (A two-year study)THE L. E. PHENOMENON IN RHEUMATOID ARTHRITIS*IRVING A. FRIEDMAN, M.D., JEROME F. SICKLEY, M.D., ROBERT M. POSKE, M.D., ARNOLD BLACK, M.D., DAVID BRONSKY, M.D., WILSON H. HARTZ JR., M.D., CHARLOTTE FELDHAKE, B.S., PAUL S. REEDER, M.D., ELI M. KATZ, M.D.The relationship of rheumatoid arthritis to periarteritis nodosa and systemic lupus erythematosusTHE SIGNIFICANCE OF THE L.E. CELL TESTThe L. E. cell testLUPOID HEPATITISDer viscerale Lupus erythematosus (Kaposi-Libman-Sacks-Syndrom) 1 March 1956Volume 44, Issue 3Page: 497-504KeywordsBloodBlood plasmaBone marrow cellsBone marrow disordersCellsHematology and oncologyLupus erythematosusResearch laboratoriesSystemic lupus erythematosusTechnicians Issue Published: 1 March 1956 PDF downloadLoading ...