FUNCTIONAL SUBAORTIC STENOSIS
Authors: Norman Brachfeld, Richard Gorlin
Journal: Annals of Internal Medicine (1961)

Article1 January 1961FUNCTIONAL SUBAORTIC STENOSISNORMAN BRACHFELD, M.D., RICHARD GORLIN, M.D.NORMAN BRACHFELD, M.D., RICHARD GORLIN, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-54-1-1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAdvances in cardiovascular surgery have naturally stimulated a reevaluation of valvular lesions which may be amenable to surgical correction. Although subaortic stenosis of the left ventricular outflow tract was first described by Chevers1in 1832, its functional significance has been largely ignored. The inability to substantiate at surgery many preoperative diagnoses of aortic valvular obstruction based on the demonstration of a left ventricular-aortic gradient has stimulated interest in other causes of obstruction to flow. A precise differential diagnosis of supravalvular, valvular, and subvalvular outflow tract obstruction is critical in the selection of the appropriate surgical procedure. Until quite recently, stenotic...Bibliography1. Chevers N: Observations on the diseases of the orifice and valves of the aorta, Guy's Hosp. Reports, p. 387, 1842. Google Scholar2. Brown JW: Congenital heart disease, 1950, Staples Press, London. Google Scholar3. Abbott ME: Atlas of congenital heart disease, 1936, Amer. Heart Ass., New York. Google Scholar4. GrishmanSteinbergSussman AMFNL: Congenital aortic and subaortic stenosis with associated anomalies of the aorta, Med. Clin. N. Amer. p. 543, 1947. CrossrefMedlineGoogle Scholar5. KeithRoweVlad JBRDP: Heart disease in infancy and childhood, 1958, The MacMillan Co., New York. Google Scholar6. Shapiro MJ: Congenital heart disease, Mod. Med. 14: 67, 1946. MedlineGoogle Scholar7. Steinberg W: Zur kenntnis des mykotischen aneurysmas der lungenschlagader, Virch. Arch. 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Author, Article, and Disclosure InformationAffiliations: Boston, Massachusetts*Received for publication May 13, 1960.Presented at the Forty-first Annual Session of The American College of Physicians, San Francisco, California, April 4-8, 1960.From the Medical Clinics of the Peter Bent Brigham Hospital and the Department of Medicine, Harvard Medical School, Boston, Mass.; and from the Department of Medicine, Cornell University Medical College, New York, N. Y.†This work was supported by grants from the U. S. Public Health Service (NIH H-2637), the Kriendler Memorial Foundation, and the Massachusetts Heart Association.‡Investigator, Howard Hughes Medical Institute.Requests for reprints should be addressed to Richard Gorlin, M.D., Peter Bent Brigham Hospital, 721 Huntington Avenue, Boston, Mass. 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