Muscle and Skin Infarction after Free-Basing Cocaine (Crack)
Authors: JORGE C. ZAMORA-QUEZADA
Journal: Annals of Internal Medicine (1988)

Brief Reports1 April 1988Muscle and Skin Infarction after Free-Basing Cocaine (Crack)JORGE C. ZAMORA-QUEZADA, M.D., HAL DINERMAN, M.D., MIGUEL J. STADECKER, M.D., Ph.D., JOHN J. KELLY, M.D.JORGE C. ZAMORA-QUEZADA, M.D., HAL DINERMAN, M.D., MIGUEL J. STADECKER, M.D., Ph.D., JOHN J. KELLY, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-108-4-564 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe use of cocaine in the United States has been rising at an alarming rate (1). Toxic effects on the central nervous system are well known, including seizures, hyperpyrexia, anxiety, and psychosis (2). More recently, cardiac toxicity with acute myocardial infarction, cardiac arrhythmias, and sudden death have been attributed to recreational use of cocaine (3). There have also been reports of cerebral infarction after cocaine inhalation (crack) (4), and renal infarction and upper extremity infarction after parenteral use (5, 6).A previously healthy 20-year-old white woman, 3 weeks before admission to New England Medical Center, suddenly developed a generalized skin...References1. CREGLERMARK LH. Medical complications of cocaine abuse. New Engl J Med. 1986;315:1495-500. CrossrefMedlineGoogle Scholar2. JONSSONO'MEARAYOUNG SMJ. Acute cocaine poisoning: importance of treating seizures and acidosis. Am J Med. 1983;75:1061-4. CrossrefMedlineGoogle Scholar3. ISNERESTESTHOMPSON JNP. Acute cardiac events temporally related to cocaine abuse. New Engl J Med. 1986;315:1438-43. CrossrefMedlineGoogle Scholar4. GOLBEMERKIN LM. Cerebral infarction in a user of free-base cocaine ("crack"). Neurology. 1986;36:1602-4. CrossrefMedlineGoogle Scholar5. HENGHABERFELD MG. Thrombotic phenomena associated with intravenous cocaine. J Am Acad Dermatol. 1987;16:462-8. CrossrefMedlineGoogle Scholar6. SHARFF J. Renal infarction associated with intravenous cocaine use. Ann Emerg Med. 1984; 13:1145-7. CrossrefMedlineGoogle Scholar7. BECKER C. Medical complications of drug abuse. Adv Intern Med. 1979;24:183-202. MedlineGoogle Scholar8. MULLICKMCALLISTERWAGNERFENOGLIO FHBJ. Drug related vasculitis: clinicopathologic correlations in 30 patients. Hum Pathol. 1979;10:313-25. CrossrefMedlineGoogle Scholar9. RALPH D. Rhabdomyolysis and acute renal failure. JACEP. 1978;7:103-6. CrossrefMedlineGoogle Scholar10. KASSIRERKOPELMAN JR. A defective detective [Clinical Conference]. Hosp Pract. 1986;21:91-8. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New England Medical Center and Tufts University School of Medicine Boston, Massachusetts PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byRadiographic Musculoskeletal Findings Indicating Opioid Misuse: An Overview for Orthopedic SurgeonsDrug-induced Nail DisordersNail Reactions to Antibiotics, Antimalarials, and Other MedicationsHistopathology and Drug AbuseInfections in Injection Drug UsersHow to Spot Cocaine-Induced PseudovasculitisLupus anticoagulant and ANCA associated thrombotic vasculopathy due to cocaine contaminated with levamisole: a case report and review of the literatureDrug-induced Nail ChangesVasculopathy, Hematological, and Immune Abnormalities Associated with Levamisole-Contaminated Cocaine UseHistopathology and Drug AbuseCocaine-related retiform purpura: evidence to incriminate the adulterant, levamisoleCocaine induces oxidative damage to skin via xanthine oxidase and nitric oxide synthaseInfections in Injection Drug UsersHeroin-associated myocardial damages—Conventional and immunohistochemical investigationsRhabdomyolysis and drug abuse in a patient with bulimia nervosaIllicit drug abuse and renal diseaseCocaine use and its rheumatic manifestations: a case report and discussionCocaïneManifestações cutâneas decorrentes do uso de drogas ilícitasSystemic DrugsCocaine-associated abscesses with lethal sepsis after splenic infarction in an 17-year-old womanCocaineInfarto renal por trombosis arterial en un paciente con variante molecular del factor II de la coagulación y abuso de cocaína inhaladaIllicit drug abuseRenal infarction: A rare complication of cocaine abuseEffects of cocaine on the coronary arteriesDiabetic thigh muscle infarction in association with antiphospholipid antibodiesAcute gastrointestinal manifestations associated with use of crackAtypical skin lesions associated with mixed cryoglobulinaemia and hepatitis C virus infection in a cocaine‐consuming patientAlcohol, social behavior disorders, and their cutaneous manifestationsRenal disease associated with illicit drug abuseSevere rhabdomyolysis with renal failure after intranasal cocaine useAcute and Chronic Cocaine Exposure Can Produce Myocardial Ischemia and Infarction in Yucatan SwineFocal necrotizing panniculitis and vascular necrosis in rats given subcutaneous injections of cocaine hydrochlorideEffects of Cocaine on Human Platelet Aggregation In VitroEffects of cocaine on leakage of creatine kinase from skeletal muscle: In vitro and in vivo studies in miceRhabdomyolysis and hyperthermia after cocaine abuse: a variant of the neuroleptic malignant syndrome?Coronary artery intimal hyperplasia, occlusive platelet thrombus, and fatal myocardial infarction in an intravenous cocaine userIntravenous Cocaine Induces Platelet Activation in the Conscious DogActivation of human platelets by cocaine.Acute rhabdomyolysis associated with acute cocaine intoxication. 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Howard, MD, William D. Kaehny, MDCocain-associated acute myoglobinuric renal failureMyonecrosis and Cocaine AbusePravin C. Singhal, MD, Marquetta Faulkner, MDRhabdomyolysis after intravenous cocaineRhabdomyolysis Associated with Cocaine Intoxication 1 April 1988Volume 108, Issue 4Page: 564-566KeywordsArrhythmiaCentral nervous systemCocaineEpileptic seizuresInfarctionInhalationMusclesRheumatologySudden cardiac deathToxicity Issue Published: 1 April 1988 PDF downloadLoading ...