Fatty Acid Deficiency
Authors: Richard C. Bozian, Joseph L. Piepmeyer
Journal: Annals of Internal Medicine (1976)

Comments1 October 1976Fatty Acid DeficiencyRICHARD C. BOZIAN, M.D., F.A.C.P., JOSEPH L. PIEPMEYER, R.D.RICHARD C. BOZIAN, M.D., F.A.C.P.Search for more papers by this author, JOSEPH L. PIEPMEYER, R.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-85-4-540 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: We write to comment on Dr. William Connor's editorial on essential fatty acid deficiency in man (Ann Intern Med83:895-896, 1975). In another paper (1) Dr. Connor and his associates report the appearance of essential fatty acid deficiency immediately upon initiating a fat-free regimen in healthy subjects, orally or parenterally, and consider the syndrome a common and significant clinical problem. In that study there was an early decrease in linoleic and arachidonic acids (ω 6 acids)*with increased eicosatrienoic, oleic, and palmitoleic acids (ω 9 acids)* in plasma cholesterol esters, phospholipids and triglycerides. Whereas the phospholipid arachidonate...References1. WENECONNORDENBESTEN JWL: The development of essential fatty acid deficiency in healthy man fed fat-free diets intravenously and orally. J Clin Invest 56:127-134, 1975 CrossrefMedlineGoogle Scholar2. GUARNEIRIJOHNSON MR: The essential fatty acids. Adv Lipid Res 8:115-174, 1970 CrossrefMedlineGoogle Scholar3. BOZIANCONIGLIO RJ: The effect of ethyl arachidonate upon eicosatrienoate levels in livers of fat deficient rats. Fed Proc 22:489, 1963 Google Scholar4. BOZIANMACGEE RJ: Total parenteral nutrition and essential fatty acid deficiency—a seven year study in short bowel syndrome. AMA Symposium on Fats in Parenteral Nutrition, Chicago, Illinois, in press, 1976 Google Scholar5. BOZIANPETERINGVILTER RHR: Trace mineral and essential fatty acid deficiency in Man: data on human requirements. Am J Clin Nutr 27:442, 1974 Google Scholar1. RIELLABROVIACWELLS MJM: Essential fatty acid deficiency in human adults during total parenteral nutrition. Ann Intern Med 83:786-789, 1975 LinkGoogle Scholar2. FREEMANSTEGINKWISPE JLJ: Prevention of post-operative essential fatty acid deficiency by infusing crystalline amino acids without dextrose. Gastroenterology 70:885, 1976 Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Division of Nutrition Department of Medicine University of Cincinnati College of Medicine Cincinnati, OH 45267*ω 9-C 16:1 palmitoleic acid, or Δ 7-C 16:1; ω 9-C 18:1, oleic acid, or A 9-C 18:1; ω 9-C 20:3 eicosatrienoic acid, or Δ 5,8,11-C 20:3; ω 6-C 18:2 linoleic acid, or Δ 9,12-C 18:2; ω 6-C 20:4 arachidonic acid, or Δ 5,8,11,14-C 20:4. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDA Standardized Approach to Parenteral Nutrition for the Geriatric Patient 1 October 1976Volume 85, Issue 4Page: 540-541KeywordsBlood plasmaCholesterolFatty acidsPhospholipids ePublished: 1 December 2008 Issue Published: 1 October 1976 PDF downloadLoading ...