PHEOCHROMOCYTOMA ASSOCIATED WITH PAINLESS MYOCARDIAL INFARCTION
Authors: M H BOLDT, M FLEXNER, A B ORTNER
Journal: Annals of Internal Medicine (1957)

Case Reports1 June 1957PHEOCHROMOCYTOMA ASSOCIATED WITH PAINLESS MYOCARDIAL INFARCTIONMARTIN H. BOLDT, M.D., F.A.C.P., MORRIS FLEXNER, M.D., F.A.C.P., ALVIN B. ORTNER, M.D., F.A.C.S.MARTIN H. BOLDT, M.D., F.A.C.P., MORRIS FLEXNER, M.D., F.A.C.P., ALVIN B. ORTNER, M.D., F.A.C.S.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-46-6-1165 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptMore than 300 cases of pheochromocytoma have been reported since Labbe, Tinel and Doumer1in 1922 first described the clinical picture in its hypertensive paroxysms. About 0.5% of all patients with hypertension are thought to have a functioning chromaffin tumor,3, 4, 5and it is estimated that between 600 and 800 people die annually from this cause.5These deaths are preventable, for the hypertension due to this tumor is curable. The clinical features of this disease, as well as the various diagnostic procedures, have been adequately described.2, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18,...Bibliography1. LabbèTinelDoumer MJ: Crises solaires et hypertension paroxystique en rapport avec une tumeur surrenale, Bull. et mém. Soc. méd. d. hôp. de Paris 46: 982, 1922, referred to by Goldenberg, M.2 Google Scholar2. GoldenbergSnyderAranow MCHH: New test for hypertension due to circulating epinephrine, J. A. M. A. 135: 971, 1947. CrossrefMedlineGoogle Scholar3. Smithwick RH, quoted by Goldenberg, M.2 Google Scholar4. SmithwickGraham RHJB, quoted by Graham, J. B.6 Google Scholar5. Gibbs DF: Application of F933 as a routine test in sustained hypertension, Edinburgh M. J. 59: 517, 1952. MedlineGoogle Scholar6. Graham JB: Pheochromocytoma and hypertension. An analysis of 207 cases, Internat. Abst. Surg. 92: 105, 1951. MedlineGoogle Scholar7. RothKvale GMWF: A tentative test for pheochromocytoma, Am. J. M. Sc. 210: 653, 1945. CrossrefGoogle Scholar8. RothKvale GMWF: A tentative test for the diagnosis of pheochromocytoma, J. Lab. and Clin. Med. 30: 366, 1945. Google Scholar9. GoldenbergAranow MH: Diagnosis of pheochromocytoma by the adrenergic blocking action of benzodioxane, J. A. M. A. 143: 1139, 1950. CrossrefMedlineGoogle Scholar10. GiffordRothKvale RWGMWF: The evaluation of the use of Regitine (C 7337) as a new pharmacologic test for pheochromocytoma, Abst., Proc. Central Soc. Clin. Research 24: 36, 1951. Google Scholar11. ShingletonBaker WWHM: Fluorometric method of determination of adrenalin in blood, Federation Proc. 8: 145, 1949. Google Scholar12. von Euler US: Increased urinary excretion of noradrenaline and adrenaline in cases of pheochromocytoma, Ann. Surg. 134: 929, 1951. CrossrefMedlineGoogle Scholar13. WeimanBackRussoShoemakerWolf CGKPEHAS: The diagnosis of pheochromocytoma by demonstration of pressor substances in the urine and by retroperitoneal pneumography, Ann. Int. Med. 41: 131, 1954. LinkGoogle Scholar14. SpearGriswold HCD: Use of Dibenamine in pheochromocytoma, New England J. Med. 239: 736, 1948. CrossrefMedlineGoogle Scholar15. Boldt M: Adrenal hypertension, J. Kentucky State M. A. 53: 201, 1955. MedlineGoogle Scholar16. LaDueMurisonPack JSPJGT: Use of tetraethylammonium bromide as a diagnostic test for pheochromocytoma, Am. J. Med. 3: 118, 1947. CrossrefMedlineGoogle Scholar17. Aranow H: Pheochromocytoma, Monographs in Medicine, 1952, The Williams and Wilkins Co., Baltimore, pp. 179-224. Google Scholar18. Aranow H: The differential diagnosis of pheochromocytoma, M. Clin. North America 34: 757-767 (May) 1950. CrossrefMedlineGoogle Scholar19. Cahill GF: Pheochromocytoma, Bull. New York Acad. Med. 29: 749, 1953. MedlineGoogle Scholar20. BartelsArnold ECWT: Essential features for the diagnosis of pheochromocytoma: report of a case, Lahey Clin. Bull. 6: 132, 1949. MedlineGoogle Scholar21. HatchRichardsSpiegel FNVRJ: Adrenal medulla tumor (pheochromocytoma), Am. J. Med. 6: 633, 1949. CrossrefMedlineGoogle Scholar22. CahillAranow GFH: Pheochromocytoma: diagnosis and treatment, Ann. Int. Med. 31: 389, 1949. LinkGoogle Scholar23. BiermanPartridge HRJW: Untoward reactions to tests in epinephrine secreting tumors (pheochromocytoma), New England J. Med. 244: 582, 1951. CrossrefMedlineGoogle Scholar24. ConleyJunkerman JECL: Lack of specificity of piperoxan hydrochloride test for adrenal medullary tumors, J. A. M. A. 147: 921, 1951. CrossrefMedlineGoogle Scholar25. Drill VA: Reactions from the use of benzodioxane (933F) in diagnosis of pheochromocytoma, New England J. Med. 241: 777, 1949. CrossrefMedlineGoogle Scholar26. GreenPeterson DMEM: Hypertensive encephalopathy after administration of benzodioxane, J. A. M. A. 142: 408, 1950. CrossrefMedlineGoogle Scholar27. Meilman E: False positive test for pheochromocytoma with an "adrenolytic" compound, New England J. Med. 245: 177, 1951. CrossrefMedlineGoogle Scholar28. Gibbs DF: Application of F933 as a routine test in sustained hypertension, Edinburgh M. J. 59: 517, 1952. MedlineGoogle Scholar29. Place VA: Piperoxan hydrochloride (benzodioxane) test, report of a false positive reaction, J. A. M. A. 148: 538, 1952. CrossrefMedlineGoogle Scholar30. Tullon HP: Negative benzodioxane test in presence of a pheochromocytoma, Brit. M. J. 1: 531, 1952. CrossrefMedlineGoogle Scholar31. EvansRubitskyBartelsBartels JAHJCCEC: Re-evaluation of the reliability of pharmacologic and cold pressor studies in hypertension and pheochromocytoma, Am. J. Med. 11: 448, 1951. CrossrefMedlineGoogle Scholar32. Soffer A: False-positive reaction to the piperoxane hydrochloride test for pheochromocytoma, J. A. M. A. 148: 538, 1952. CrossrefMedlineGoogle Scholar33. WingoWilliamsWade CFJPFA: Pheochromocytoma: two case reports with unusual reactions and a general review, Ann. Int. Med. 42: 856, 1955. LinkGoogle Scholar34. Rabin CB: Chromaffin cell tumor of the suprarenal medulla (pheochromocytoma), Arch. Path. 7: 228, 1929. Google Scholar35. PitcairnYoumans DMWB: Potent pressor action of an extract of a pheochromocytoma after adrenolytic doses of Dibenamine, Federation Proc. 8: 437, 1949. Google Scholar36. Holton P: Noradrenaline in adrenal medullary tumors, Nature, London 163: 217, 1949. CrossrefMedlineGoogle Scholar37. GoldenbergSerlinEdwardsRapport MITMM: Chemical screening methods for the diagnosis of pheochromocytoma; nor-epinephrine and epinephrine in human urine, Am. J. Med. 16: 310, 1954. CrossrefMedlineGoogle Scholar38. von Euler US: Increased urinary excretion of nor-adrenaline and adrenaline in cases of pheochromocytoma, Ann. Surg. 134: 929, 1951. CrossrefMedlineGoogle Scholar39. Priest WM: Pheochromocytoma with fatal myocardial infarction in a man aged 22, Brit. M. J. 2: 860, 1952. CrossrefMedlineGoogle Scholar40. Roseman MD: Painless myocardial infarction: a review of the literature and analysis of 220 cases, Ann. Int. Med. 41: 1, 1954. LinkGoogle Scholar41. CahillMontieth GFJC: The use of Dibenamine and nor-epinephrine in the operative treatment of pheochromocytoma: report of two cases, New England J. Med. 244: 657, 1951. CrossrefMedlineGoogle Scholar42. MandevilleSahyoun FBPF: Benign and malignant pheochromocytoma with necropsies: benign case with multiple neurofibromatosis and cavernous hemangioma of fourth ventricle: malignant case with widespread metastasis and bronchogenic carcinoma, J. Urol. 62: 93, 1949. CrossrefMedlineGoogle Scholar43. MacKeith R: Adrenal-sympathetic syndrome: chromaffin tissue tumor with paroxysmal hypertension, Brit. Heart J. 6: 1, 1944. CrossrefMedlineGoogle Scholar44. GlushienMansuyLittman ASMMDS: Pheochromocytoma—its relationship to the neurocutaneous syndromes, Am. J. Med. 14: 318, 1953. CrossrefMedlineGoogle Scholar45. Smithwick RH: Surgical treatment of hypertension, Am. J. Med. 4: 744, 1948. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Louisville, Kentucky*Received for publication January 23, 1956.From the Department of Medicine and Surgery, University of Louisville, School of Medicine.Requests for reprints should be addressed to Martin H. Boldt, M.D., 719 Heyburn Building, Louisville 2, Kentucky. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byCardiovascular Manifestations and Complications of Pheochromocytomas and ParagangliomasRecurrent Takotsubo Cardiomyopathy Associated with PheochromocytomaMyocardial Infarction and Reversible Left Ventricular Apical Ballooning Associated With PheochromocytomaCatastrophic Cardiac Hypokinesis and Multiple-Organ Failure After Surgery in a Patient With an Undiagnosed Pheochromocytoma: Emergency Excision of the TumorAcute reversal of pheochromocytoma-induced catecholamine cardiomyopathyPheochromocytoma associated ventricular tachycardia blocked with atenololPhaeochromocytoma and cardiomyopathyPhaeochromocytoma and acute cardiovascular death (with special reference to myocardial infarction).PHÆOCHROMOCYTOMA AND MYOCARDIAL INFARCTIONCardiac complications of phaeochromocytoma.BibliographySuccessful removal of a pheochromocytoma four weeks after acute myocardial infarction∗Pheochromocytoma and Meningioma of the Foramen MagnumARNOLD GREENHOUSE, M.D.Pheochromocytoma in the adult and in the childPheochromocytoma associated with multiple neurofibromatosis and intracranial hemangioma 1 June 1957Volume 46, Issue 6Page: 1165-1177KeywordsElectrocardiographyHemorrhageHypertensionHypotensionMyocardial infarctionPheochromocytomaSurgerySyncope ePublished: 1 December 2008 Issue Published: 1 June 1957 PDF downloadLoading ...