FATAL METHEMOGLOBINEMIA DUE TO WELL WATER NITRATES
Authors: ROBERT BUCKLIN
Journal: Annals of Internal Medicine (1960)

Case Reports1 March 1960FATAL METHEMOGLOBINEMIA DUE TO WELL WATER NITRATESROBERT BUCKLIN, M.D., F.A.C.P., M. K. MYINT, M.D.ROBERT BUCKLIN, M.D., F.A.C.P.Search for more papers by this author, M. K. MYINT, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-52-3-703 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAmong the many causes of acquired methemoglobinemia, that due to ingestion of well water containing high levels of nitrates is an entity one should consider in a cyanotic infant with a negative history and physical findings. Some other causes of methemoglobinemia are aniline, phenacetin, acetanilid, sulfonamides, nitrobenzene, various nitrites, nitroglycerin, bismuth subnitrate, ammonium nitrates, contact with dyed blankets, laundry marks on diapers, freshly dyed shoes, inhalation of nitrous gases in arc welding, and ingestion of crayons containing p-nitroaniline.5Methemoglobin is a derivative of hemoglobin, where ferrous porphyrin complex is converted to the ferric form, which does not combine with oxygen.3...Bibliography1. : Water supply: nitrate in potable waters and methemoglobinemia, A. P. H. A. Yearbook 40, 5: 110 (May) 1949-1950. Google Scholar2. CornblathHartman MAF: Methemoglobinemia in young infants, J. Pediat. 33: 421-425 (Oct.) 1948. CrossrefMedlineGoogle Scholar3. Finch CA: Methemoglobinemia and sulfhemoglobinemia, J. Clin. Investigation 28: 265, 1949. MedlineGoogle Scholar4. LembergLegge RJW: Hematin compounds and bile pigments, 1949, Interscience Publications, Inc., New York, quoted by Wintrobe.5 Google Scholar5. Wintrobe M: Clinical hematology, 4th Ed., 1956, Lea and Febiger, Philadelphia, pp. 174-176. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Saginaw, Michigan*Received for publication October 16, 1958.From the Department of Pathology, Saginaw General Hospital, Saginaw, Michigan.Requests for reprints should be addressed to Robert Bucklin, M.D., 1447 North Harrison Street, Saginaw, Michigan. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByAcute Methemoglobinemia Following Attempted Suicide by DapsonNoninvasive in vivo monitoring of methemoglobin formation and reduction with broadband diffuse optical spectroscopyMethemoglobinemiaUnexplained acute severe methaemoglobinaemia in a young adultExperimental Studies of Methemoglobinemia Due to Percutaneous Absorption of Sodium NitriteFatal Methemoglobinemia Caused by Liniment Solutions Containing Sodium NitriteMethemoglobinemia Caused by the Accidental Contamination of Drinking Water with Sodium NitriteSaltpeter ingestionAmyl nitrite-induced hemolytic anemiaAmmonium nitrate cold pack ingestionHematologic Aspects of ToxicologyDrug- and Chemical-Induced MethaemoglobinaemiaMethemoglobin levels in the patient population of an acute general hospitalMethemoglobinemiaFatal Methemoglobinemia Resulting from Ingestion of Isobutyl Nitrite, a “Room Odorizer” Widely Used for Recreational PurposesThe Metabolism of Methemoglobin in Human ErythrocytesNitrates, nitrites, and methemoglobinemiaMethemoglobinemia from Well Water Nitrates: A Complication of Home DialysisDAVID J. CARLSON, M.D., FRED L. SHAPIRO, M.D.Successful Treatment of Methemoglobinemia Secondary to Silver Nitrate TherapyReproduction in the guinea pig as affected by chronic administration of potassium nitrate and potassium nitrite 1 March 1960Volume 52, Issue 3Page: 703-705KeywordsHemoglobinInfantsIngestionMethemoglobinemiaNitratesOral administrationPancreasPorphyrinsRespirationSulfonamide Issue Published: 1 March 1960 PDF DownloadLoading ...