Myoglobinuric Myopathy
Authors: CONSTANTINE L. HAMPERS
Journal: Annals of Internal Medicine (1964)

Case Studies1 March 1964Myoglobinuric MyopathyA Clinical, Histological, and Biochemical StudyCONSTANTINE L. HAMPERS, M.D., DAVID PRAGER, M.D.CONSTANTINE L. HAMPERS, M.D.Search for more papers by this author, DAVID PRAGER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-60-3-476 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe occurrence of myoglobin in the urine has been well-established in various conditions. These include severe exercise (1), crush syndrome (2), electric shock (3), arterial occlusion (4), barbiturate intoxication (5), polymyositis (6), Haff's disease (7), McArdle's syndrome (8), regional enteritis (9), infections (10), in the postictal state (11), in muscular dystrophy (12), and with acute alcoholic intoxication (5).In a certain number of cases no cause can be found, and these necessarily have been classified as "idiopathic." Approximately 60 cases have been reported since 1910 when Meyer-Betz (13) first described this condition. Efforts have been made to better understand this...References1. HOWENSTEIN JA: Exertion-induced myoglobinuria and hemoglobinuria. JAMA 173: 493, 1960. CrossrefMedlineGoogle Scholar2. BYWATERSDELACYREMINGTONSMILES EGGECJ: Myohemoglobin in the urine of air raid casualties with crushing injury. Biochem. J. 35: 1164, 1941. CrossrefMedlineGoogle Scholar3. FISCHERROSSIER HPH: Starkstrommunfälle mit schweren muskelschadigungen und myoglobinurie. Helv. 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HAMPERS, M.D.; DAVID PRAGER, M.D.From the Philadelphia General Hospital, Philadelphia, Pennsylvania.Requests for reprints should be addressed to Constantine L. Hampers, M.D., Philadelphia General Hospital, 34th and Curie Streets, Philadelphia, Pennsylvania 19104. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byIdiopathic rhabdomyolysis 1 March 1964Volume 60, Issue 3Page: 476-485KeywordsElectron microscopyEnzymesHospital medicineIntoxicationMuscular diseasesMuscular dystrophiesPhagocytosisPolymyositisShockUrine ePublished: 1 December 2008 Issue Published: 1 March 1964 PDF downloadLoading ...