STUDIES ON THE MECHANISM OF CARDIAC INJURY IN EXPERIMENTAL HYPOTHERMIA
Authors: K LANGE, D WEINER, M M A GOLD
Journal: Annals of Internal Medicine (1949)

Article1 December 1949STUDIES ON THE MECHANISM OF CARDIAC INJURY IN EXPERIMENTAL HYPOTHERMIAKURT LANGE, M.D., DAVID WEINER, M.D., MICHAEL M. A. GOLD, M.D.KURT LANGE, M.D., DAVID WEINER, M.D., MICHAEL M. A. GOLD, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-31-6-989 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThere are numerous reports in the literature that subsequent to exposure to severe cold accompanied by a lowering of body temperature severe cardiac irregularities or sudden death may occur. These effects may occur even up to 24 hours after the exposure when the body temperature has long since returned to normal.1-6 Such instances were encountered during the war with previous exposure to cold water (immersion) or with certain therapeutic uses of cold as an adjuvant in the treatment of malignancy. Numerous investigators have attempted to explain the hypothermic death but no single theory has found general acceptance.Ariel, Bishop and...Bibliography1. WAYBURN E: Immersion hypothermia, Arch. Int. Med., 1947, lxxix, 77. CrossrefGoogle Scholar2. UNGLEY CC: Research and development of life saving equipment. Medical aspects of shipwreck. British Intelligence Objectives Sub-Committee Final Report No. 494, Item No. 24. Google Scholar3. ALEXANDER L: The treatment of shock from prolonged exposure to cold, especially in water. Combined Intelligence Objectives Sub-Committee. Google Scholar4. SMITH LW: The use of cold in medicine, Ann. Int. Med., 1942, xvii, 618. Google Scholar5. KOSSMANN E: General crymotherapy. A Symposium. Cardiovascular aspects, Bull. N. Y. Acad. Med., 1940, xvi, 317. Google Scholar6. TOMASZEWSKI W: Changements electrocardiographiques observés chez un homme mort de froid, Arch. de mal de froid, 1938, xxxi, 525. Google Scholar7. 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Combined Intelligence Objectives, Sub-Committee. Google Scholar13. LANGEWEINERBOYD KDLJ: The functional pathology of experimental immersion foot, Am. Heart Jr., 1948, xxxv, 238. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Received for publication December 16, 1948.From the Department of Medicine, New York Medical College, Flower and Fifth Avenue Hospitals and the New York Medical College Research Unit (Metropolitan Hospital).Carried out under a contract between the Research and Development Board of the Surgeon General, U. S. Army and the New York Medical College. 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