TRANSIENT ELECTROCARDIOGRAPHIC CHANGES SIMULATING AN ACUTE MYOCARDITIS IN SERUM SICKNESS
Authors: D H NEUSTADT
Journal: Annals of Internal Medicine (1953)

Case Reports1 July 1953TRANSIENT ELECTROCARDIOGRAPHIC CHANGES SIMULATING AN ACUTE MYOCARDITIS IN SERUM SICKNESSDAVID H. NEUSTADT, M.D.DAVID H. NEUSTADT, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-39-1-126 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThis case report describes changes in T wave compatible with an acute myocarditis found in a routine electrocardiogram taken on a young woman with generalized allergic manifestations caused by horse serum. With subsidence of the allergic phenomena two days later, the electrocardiographic abnormalities disappeared.CASE REPORTA 27 year old white single woman entered the hospital for the first time with generalized urticaria, joint pains and bilateral periorbital edema. Nine days before she had sustained a small puncture wound from a rusty nail which was treated in the Lenox Hill Hospital Emergency Room. An intradermal test with tetanus antitoxin was...Bibliography1. LilienfeldHochsteinWeiss AEW: Acute myocarditis with bundle branch block due to sulfonamide sensitivity, Circulation 1: 1060, 1950. CrossrefGoogle Scholar2. FosterLayman RFJD: Electrocardiogram resembling coronary occlusion accompanying generalized urticaria, J. A. M. A. 148: 203, 1952. CrossrefMedlineGoogle Scholar3. Jaffe R: Las Lesiones Miocardicas y Hepaticas en Annules Alergicos, Rev. sudam. Morfol. 4: 107, 1946. MedlineGoogle Scholar4. Klinge F: Die Eiweissüberempfindlichkeit der Gelenke, Beitr. z. path. Anat. u. z. allg. Path. 89: 374, 1932. Google Scholar5. Bruun E: Allergische Arthritis und Myokarditis, Virchows Arch. f. path. Anat. 303: 524, 1939. CrossrefGoogle Scholar6. RichGregory ARJE: Experimental evidence that lesions with basic characteristics of rheumatic carditis can result from anaphylactic hypersensitivity, Bull. Johns Hopkins Hosp. 72: 65, 1943. Google Scholar7. FoxJones RALR: Vascular pathology in rabbits following administration of foreign protein, Proc. Soc. Exper. Biol. and Med. 55: 294, 1944. CrossrefGoogle Scholar8. Longcope WT: Serum sickness and analogous reaction from certain drugs, particularly the sulfonamides, Medicine 22: 251, 1943. CrossrefGoogle Scholar9. Jaffe RH: General considerations on pathogenesis of syphilitic aortitis, myocarditis, hepatic cirrhosis, J. Lab. and Clin. Med. 29: 139, 1944. Google Scholar10. BrownMcNamara CEDH: Acute interstitial myocarditis following administration of arsphenamine, Arch. Dermat. and Syph. 42: 312, 1940. CrossrefGoogle Scholar11. FrenchWeller AJCV: Interstitial myocarditis following clinical and experimental use of sulfonamide drugs, Am. J. Path. 18: 109, 1942. MedlineGoogle Scholar12. WellsSax AHSG: Isolated myocarditis probably of sulfadiazine origin, Am. Heart J. 30: 522, 1945. CrossrefMedlineGoogle Scholar13. Goodman MJ: Periarteritis with recovery: report of unusual case apparently due to sensitivity to sulfonamide, Ann. Int. Med. 28: 181, 1948. LinkGoogle Scholar14. ClarkKaplan EBI: Endocardial, arterial and other mesenchymal alterations associated with serum sickness, Arch. Path. 24: 458 (Oct.) 1937. Google Scholar15. WadsworthBrown GHCH: Serum reaction complicated by acute carditis, J. Pediat. 17: 801 (Dec.) 1940. CrossrefGoogle Scholar16. FoxMesseloff TTCR: Electrocardiographic changes in a case of serum sickness due to tetanus antitoxin, New York State J. Med. 42: 152, 1942. Google Scholar17. McKinley CA: Allergic carditis, pericarditis and pleurisy; report of case of serum sickness with predominant cardiac manifestation and symptomatic recovery, Journal Lancet 68: 61 (Feb.) 1948. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Received for publication November 14, 1952.From the Cardiovascular Service, Lenox Hill Hospital, New York, N. Y. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byZur Immunpathogenese perimyokardialer ErkrankungenMyokarditisDie essentielle MyokardiopathieCardiovascular SystemThe clinical spectrum of primary myocardial diseaseMyokarditis und weitere MyokardiopathienRecurrent ventricular tachycardia as the chief manifestation of myocarditis of unknown etiologyAcute Pericarditis after Smallpox VaccinationThe electrocardiogram in hypersensitivity reactionsKrankheiten des MyokardsAcute Pericarditis Associated with Serum Sickness 1 July 1953Volume 39, Issue 1Page: 126-131KeywordsAntitoxinsArthralgiaEdemaElectrocardiographyEmergency departmentMyocarditisTetanusUrticaria ePublished: 1 December 2008 Issue Published: 1 July 1953 PDF downloadLoading ...