The Effect of Irradiated Ergosterol on the Thrombocytes and the Coagulation of the Blood
Authors: R. A. Phillips, D. F. Robertson, W. C. Corson, G. F. Irwin
Journal: Annals of Internal Medicine (1931)

Article1 March 1931The Effect of Irradiated Ergosterol on the Thrombocytes and the Coagulation of the BloodR. A. PHILLIPS, M. D., D. F. ROBERTSON, M. D., W. C. CORSON, M. D., G. F. IRWIN, M.D.R. A. PHILLIPS, M. D.Search for more papers by this author, D. F. ROBERTSON, M. D.Search for more papers by this author, W. C. CORSON, M. D.Search for more papers by this author, G. F. IRWIN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-4-9-1134 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIt has of course been known since the work of Zizzozero and Wooldridge that the thrombocytes are a definite factor in aiding coagulation and with their increase it has been shown by Duke1that the coagulation time of the blood is diminished. Gunn2with the ultra-violet light produced an increase of thrombocytes in rabbits. "The increase varied from 40%-100% of the original normal but always amounted to at least twice that of the normal variation in the animal." It occurred to us in considering this latter work that this action might be due to the vitamin D affected on the...References1 DUKE WW: J. A. M. A., 1910, 51:1185. CrossrefGoogle Scholar2 GUNN FD: Proc Soc. Exp. Biol. & Med., 1926, 24:120. CrossrefGoogle Scholar3 CRAMERDREWMOTTRAM : Proc. Royal Soc. London, 1922, xciii, 449. Google Scholar4 SOOEYLAURENS JWH: Proc. Soc. Exp. Biol. & Med., 1924, 22:116. CrossrefGoogle Scholar5 REESECKER HMEE: J. A. M. A., 1923, 80:621. CrossrefGoogle Scholar6 BROUGHER JC: Science 1928, 68:256. CrossrefMedlineGoogle Scholar7 SOOYMOISE JWTS: J. A. M. A., 1926, 87:94. CrossrefGoogle Scholar8 SELYE H: Klin. Wchnschr., 1928, 7:1891. CrossrefGoogle Scholar9 MOISESOOY TSJW: J. Lab. & Clin. Med., 1927, 12:1113. Google Scholar10 BOGGS TR: Internat. Clin. Phils., 1908, 1:31. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: St. Louis, Mo.*(From the Department of Surgery, Washington University School of Medicine, and Barnes Hospital, S. Louis, Mo.) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byA Legacy in 20th‐Century Medicine: Robert Allan Phillips and the Taming of CholeraThe bleeding tendency in diseases of the liver and biliary passages1Hemostatic Effects of Administration of Calcium, Viosterol, Styptysate, and Ceanothyn by Mouth**From the Department of Physiology and Pharmacology, College of Physicians and Surgeons, A School of Dentistry.*Supported in part by grants from the California State Dental Association and from the Research Commission of the American Dental Association.LXXXV. Seasonal Variations in Blood Coagulation—A Study Based on 1676 CasesThe role of serum-calcium fractions in the effect of viosterol on the bleeding tendency in jaundiceAntivenin in thrombocytopenic hemorrhage 1 March 1931Volume 4, Issue 9Page: 1134-1143KeywordsFibrinogenHospital medicineRabbitsSurgeryVitamin D ePublished: 1 December 2008 Issue Published: 1 March 1931 PDF downloadLoading ...