BARBITURATE POISONING: COMBINED USE OF RESPIRATOR, FLUID, CENTRAL NERVOUS SYSTEM STIMULANTS AND PRESSOR AGENTS
Authors: K T DRESDALE, H L MOTLEY
Journal: Annals of Internal Medicine (1948)

Case Reports1 March 1948BARBITURATE POISONING: COMBINED USE OF RESPIRATOR, FLUID, CENTRAL NERVOUS SYSTEM STIMULANTS AND PRESSOR AGENTSDAVID T. DRESDALE, M.D., HURLEY L. MOTLEY, M.D., JOHN R. WEST, M.D., JAMES K. ALEXANDER, M.D.DAVID T. DRESDALE, M.D.Search for more papers by this author, HURLEY L. MOTLEY, M.D.Search for more papers by this author, JOHN R. WEST, M.D.Search for more papers by this author, JAMES K. ALEXANDER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-28-3-676 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThis case is presented to demonstrate the use of a respirator, combined with parenteral fluids, central nervous system stimulants and pressor agents, in sustaining life for three days in a patient deeply comatose from barbiturate poisoning.The patient was a 63 year old hypertensive and diabetic white woman, with suicidal tendencies, who had taken, as well as could be determined, approximately 2 gm. of Sodium Seconal and 0.6 gm. of Sodium Amytal, eight to ten hours before admission to the emergency ward at Bellevue Hospital. At the time of admission the patient was deeply cyanotic, unresponsive to stimuli, a-reflexic and...Bibliography1. MOTLEYCOURNANDECKMANRICHARDS HLAMDW: Physiological studies on man with the pneumatic balance resuscitator, "Burns Model," Jr. Aviation Med., 1946, xvii, 431-461. Google Scholar2. BURNS HL: Pneumatic balance resuscitator, Air. Surg. Bull., 1945, ii, 306-307. Google Scholar3. MOTLEYCOURNANDWERKOHIMMELSTEINDRESDALEJOHNSONLESTERSPIERTORICHARDS HLALADRMBDW: Physiological and clinical studies of intermittent pressure respirators and manual methods for producing artificial respiration in man. Memorandum Report, TSEAA-696-79-F, AAF, Hdqs., Eng. Div., Aero-Medical Laboratory, Wright Field (Sept. 6) 1946. Google Scholar4. KEYSVIOLANTE AA: The cardio-circulatory effects in man of neosynephrin, Jr. Clin. Invest., 1942, xxi, 1-12. CrossrefGoogle Scholar5. LANDISGEITER AMCW: Preparation of and cardiovascular response to neosynephrin in oil, Proc. Soc. Exper. Biol. and Med., 1943, liii, 52-54. CrossrefGoogle Scholar6. JOHNSON CA: A study of neosynephrin hydrochloride in the treatment of acute shock from trauma or hemorrhage, Surg., Gynec., and Obst., 1936, lxiii, 35-42. Google Scholar7. LORHANLALICH PHJJ: Circulatory and electrocardiographic studies of neosynephrin hydrochlorid in spinal anesthesia, Anesth. and Analg., 1940, xix, 66-75. Google Scholar8. BUNNERDE TAKATS RG: Neosynephrin in spinal anesthesia, Jr. Am. Med. Assoc., 1939, xii, 877. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Received for publication June 20, 1947.From the Department of Medicine, Columbia University, College of Physicians and Surgeons; and the First Medical Division and Chest Service, Bellevue Hospital, New York, N. Y.This work was supported in part under a contract with the Aero Medical Laboratory, Wright Field, Dayton, Ohio. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAcute Pulmonary Edema Caused by Barbiturate PoisoningTHERAPY OF ACUTE BARBITURATE POISONING: REPORT OF THREE CASES*MARCEL ROCHE, M.D., LYMAN C. WYNNE, M.D., DONALD M. HASKINS, M.D. 1 March 1948Volume 28, Issue 3Page: 676-681KeywordsCentral nervous systemComaEmergency departmentHospital medicineResearch laboratoriesSodiumSurgeonsThoraxVentilators ePublished: 1 December 2008 Issue Published: 1 March 1948 PDF downloadLoading ...