THE RATIONAL APPROACH IN THE USE OF BRONCHODILATORS IN CHRONIC RESPIRATORY DISEASE
Authors: S M FARBER, R H WILSON
Journal: Annals of Internal Medicine (1959)

Article1 May 1959THE RATIONAL APPROACH IN THE USE OF BRONCHODILATORS IN CHRONIC RESPIRATORY DISEASESEYMOUR M. FARBER, M.D., ROGER H. L. WILSON, M.D.SEYMOUR M. FARBER, M.D.Search for more papers by this author, ROGER H. L. WILSON, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-50-5-1241 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptPharmacologic bronchodilators have been used perhaps as long as any known medicinal agent. The use of ephedrine (ma hwang) is shrouded in the mists of Chinese antiquity. The burning of stramonium leaves appears at least as early as the 17th Century in Western Europe. Thus, sympatheticomimetic substances and parasympathetic paralysants appear early in the treatment of "bronchospastic" disease. Today many different compounds are available to be used as bronchodilators. These fall largely into three groups:1. Epinephrine and related compounds.2. Derivatives of scopolamine or hyoscyamine.3. Aminophylline and other related substances.The route of administration, choice of drug, dosage...Bibliography1. McIlroyChristie MBRV: Post-mortem study of visco-elastic properties of lungs in emphysema, Thorax 7: 295, 1952. CrossrefMedlineGoogle Scholar2. LanderDavidson FPM: Aetiology of bronchiectasis (with special reference to pulmonary atelectasis), Brit. J. Radiol. 11: 65, 1938. CrossrefGoogle Scholar3. LanderDavidson FPM: Pathogenesis of bronchiectasis, Brit. M. J. 1: 1047, 1938. CrossrefMedlineGoogle Scholar4. Dayman HG: Mechanics of air flow in health and emphysema, J. Clin. Investigation 30: 1175, 1951. CrossrefMedlineGoogle Scholar5. Dayman HG: Mechanical factors governing expiratory obstruction to airflow (motion picture), Chronic Disease Research Institute, University of Buffalo School of Medicine, Buffalo, N. Y., 1955. Google Scholar6. Dayman HG: Airflow patterns in health and in the presence of pulmonary disease, Monograph, aided by Muscle Dystrophy Association, 1954. Google Scholar7. WilsonGrimesMiyanishi RHOFM: Physiologic criteria for surgery in pulmonary emphysema, Abstract, Fifth International Congress on Diseases of the Chest, American College of Chest Physicians, Tokyo, 1958. Google Scholar8. AbbottVan FletRobertoSalomone OAWEAEFP: Studies on the function of the human vagus nerve in various types of intrathoracic disease, J. Thoracic Surg. 30: 564, 1955. CrossrefGoogle Scholar9. BarachBeck ALGJ: The ventilatory effects of the head-down position in pulmonary emphysema, Am. J. Med. 26: 55, 1954. CrossrefGoogle Scholar10. FowlerHelmholzMiller WSHFRD: Treatment of pulmonary emphysema with aerosolized bronchodilator drugs and intermittent positive pressure breathing, Proc. Staff Meet., Mayo Clin. 28: 743, 1953. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: SEYMOUR M. FARBER, M.D.; ROGER H. L. WILSON, M.D.Affiliations: San Francisco, California*Received for publication November 18, 1957.From the Department of Medicine, University of California School of Medicine, and the San Francisco Department of Health, San Francisco Hospital, San Francisco, California.Requests for reprints should be addressed to Seymour M. Farber, M.D., University of California Service Ward 62, San Francisco Hospital, San Francisco, California. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byTHE MANAGEMENT OF ASTHMATIC PATIENTS IN A CASUALTY DEPARTMENT 1 May 1959Volume 50, Issue 5 Page: 1241-1251 Keywords Bronchodilators Drugs Edema Emphysema Epinephrine Falls Hospital medicine Pulmonary diseases Respiration Routes of administration ePublished: 1 December 2008 Issue Published: 1 May 1959 PDF downloadLoading ...