ATROPINE POISONING: REPORT OF TWO CASES
Authors: V W GROISSER
Journal: Annals of Internal Medicine (1956)

Case Reports1 May 1956ATROPINE POISONING: REPORT OF TWO CASESVICTOR W. GROISSER, M.D.VICTOR W. GROISSER, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-44-5-1020 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlthough atropine poisoning has occasionally occurred following overdosage with suicidal intent, and after the ingestion of wild berries ofAtropa belladonna, the great majority of reported cases have been therapeutic accidents, resulting from carelessness on the part of physicians, pharmacists, patients and unskilled hospital aides. Fortunately, mortality is uncommon because of the rapid excretion and inactivation of the drug, but the affected patients are often violently ill. After observing a near-fatal episode of poisoning in a child in 1929, Heller1concluded that future morbidity and mortality could be prevented by the use of the word "POISON" on bottles of atropine...Bibliography1. Heller G: Atropine poisoning in a child, J. A. M. A. 92: 800 (Mar. 9) 1929. CrossrefGoogle Scholar2. GoodmanGilman LA: The pharmacological basis of therapeutics, 1941, Macmillan Company, New York. Google Scholar3. HydeTorndorfChinn RWJHI: Absorption from the nasal mucous membrane, Ann. Otol., Rhin. and Laryng. 62: 957 (Dec.) 1953. CrossrefGoogle Scholar4. ListwanWhealy IANC(a) : Mental symptoms in poisoning with atropine and its derivatives, M. J. Australia 1: 581 (Apr. 25) 1953. (b) Morton, H. G.: Atropine intoxication; its manifestations in infants and children, J. Pediat. 14: 755 (June) 1939. (c) Dameshek, W., and Feinsilver, O.: Human autonomic pharmacology: use of acetylbeta methyl choline chloride (Mecholyl) as diagnostic test for poisoning by atropine series of drugs, J. A. M. A. 109: 561 (Aug. 21) 1937. (d) Duggan, P. J.: Mental disturbance following atropine administration, Brit. M. J. 1: 918 (May 1) 1937. (e) Metevier, V. M.: A case of atropine poisoning, Lancet 2: 1232 (Nov. 30) 1935. CrossrefMedlineGoogle Scholar5. Gold H: Cornell Conference on therapy: household poisonings, Am. J. Med. 6: 237 (Feb.) 1949. CrossrefMedlineGoogle Scholar6. Wolfson S: Atropine poisoning—case report, Anesthesiology 7: 566 (Sept.) 1946. CrossrefMedlineGoogle Scholar7. Personal communication. Google Scholar8. WilbournBuxton RBJD: Acute atropine poisoning, review of eight cases, Lancet 2: 211 (Aug. 7) 1948. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Received for publication October 10, 1955.†Senior Assistant Surgeon, U. S. Public Health Service; presently Assistant Resident in Medicine, Mount Sinai Hospital, New York, N. Y. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySome Antagonists of Atropine-Like PsychotomimeticsThe Treatment of Acute Poisoning 1 May 1956Volume 44, Issue 5Page: 1020-1024KeywordsAtropineHospital medicineIntoxicationMedical servicesMortalityPsychosesSodiumSurgeonsTachycardiaUrination Issue Published: 1 May 1956 PDF downloadLoading ...