Update in General Internal Medicine: Evidence Published in 2011
Authors: Robert C. Brooks
Journal: Annals of Internal Medicine (2012)

Updates1 May 2012Update in General Internal Medicine: Evidence Published in 2011Robert C. Brooks, MD, PhD, Peggy B. Hasley, MD, MHSc, Harish Jasti, MD, and David Macpherson, MD, MPHRobert C. Brooks, MD, PhDFrom the University of Pittsburgh School of Medicine, Veterans Affairs Pittsburgh Healthcare System, and the 4th Veterans Integrated Service Network, Pittsburgh, Pennsylvania., Peggy B. Hasley, MD, MHScFrom the University of Pittsburgh School of Medicine, Veterans Affairs Pittsburgh Healthcare System, and the 4th Veterans Integrated Service Network, Pittsburgh, Pennsylvania., Harish Jasti, MDFrom the University of Pittsburgh School of Medicine, Veterans Affairs Pittsburgh Healthcare System, and the 4th Veterans Integrated Service Network, Pittsburgh, Pennsylvania., and David Macpherson, MD, MPHFrom the University of Pittsburgh School of Medicine, Veterans Affairs Pittsburgh Healthcare System, and the 4th Veterans Integrated Service Network, Pittsburgh, Pennsylvania.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-156-9-201205010-00410 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail In 2011, investigators published several important studies that require general internists to consider practice change. Although the publications summarized here cover a broad spectrum of issues that general internists commonly face, they reflect 1 broad theme: Current practice behaviors should offer value in terms of improving meaningful clinical outcomes. The lack of evidence for improved cardiovascular outcomes with combinations of lipid-lowering agents compared with a high-dose statin regimen (1) and the lack of evidence for improved mortality with heparin prophylaxis in hospitalized medical patients, with inpatient treatment of low-risk pulmonary embolism (PE) or with prostate and ovarian cancer screening, highlight ...References1. Sharma M, Ansari MT, Abou-Setta AM, Soares-Weiser K, Ooi TC, Sears M, et al. Systematic review: comparative effectiveness and harms of combination therapy and monotherapy for dyslipidemia. Ann Intern Med. 2009;151:622-30. [PMID: 19884623] LinkGoogle Scholar2. Sirovich BE, Woloshin S, Schwartz LM. Too little? Too much? 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[PMID: 21868086] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From the University of Pittsburgh School of Medicine, Veterans Affairs Pittsburgh Healthcare System, and the 4th Veterans Integrated Service Network, Pittsburgh, Pennsylvania.Acknowledgment: The authors thank Christine Brush for her exceptional organizational work in preparing this Update and the members of the Division of General Internal Medicine Journal Club at the University of Pittsburgh for their input about the appropriateness of journal articles to include in the Update.Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M12-0186.Corresponding Author: David Macpherson, MD, MPH, 323 North Shore Drive, Suite 400, Pittsburgh, PA 15212; e-mail, David.[email protected]gov.Current Author Addresses: Dr. Brooks: Pittsburgh VA Healthcare System, University Drive C, 130-U, Pittsburgh, PA 15240.Dr. Hasley: University of Pittsburgh, 200 Lothrop Street, Pittsburgh, PA 15213.Dr. Jasti: University of Pittsburgh, 200 Lothrop Street, MUH 9W33, Pittsburgh, PA 15213.Dr. Macpherson: University of Pittsburgh, 323 North Shore Drive, Suite 400, Pittsburgh, PA 15212.Author Contributions: Conception and design: P.B. Hasley, H. Jasti, D. Macpherson.Analysis and interpretation of the data: R.C. Brooks, P.B. Hasley, H. Jasti, D. Macpherson.Drafting of the article: R.C. Brooks, P.B. Hasley, H. Jasti, D. Macpherson.Critical revision of the article for important intellectual content: R.C. Brooks, P.B. Hasley, H. Jasti, D. Macpherson.Final approval of the article: R.C. Brooks, P.B. Hasley, H. Jasti, D. Macpherson.Administrative, technical, or logistic support: D. Macpherson.Collection and assembly of data: R.C. Brooks, P.B. Hasley, H. Jasti, D. Macpherson. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 May 2012Volume 156, Issue 9Page: 649-653KeywordsCancer screeningComputed axial tomographyHemorrhageHeparinHypertensionInpatientsLung and intrathoracic tumorsOutpatientsStroke ePublished: 1 May 2012 Issue Published: 1 May 2012 PDF DownloadLoading ...