THE HEMATOPOIETIC RESPONSE FOLLOWING ORAL ADMINISTRATION OF DESICCATED DUODENAL MUCOSA
Authors: John C. Thompson
Journal: Annals of Internal Medicine (1937)

Article1 July 1937THE HEMATOPOIETIC RESPONSE FOLLOWING ORAL ADMINISTRATION OF DESICCATED DUODENAL MUCOSAJOHN C. THOMPSON, F.A.C.P.JOHN C. THOMPSON, F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-11-1-39 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe fundamental work of Castle and his coworkers1, 2, 3, 4proving that a definite antianemic substance, "Intrinsic Factor," is produced in the wall of the stomach, at present seems to be established beyond a reasonable doubt. The theories developed by the author on the basis of this monumental discovery have, however, been questioned by a number of observers. Some of these objections, notably those of Greenspon,5have had to do with the nature of the antianemic material and the method of its production in the stomach. A more serious discrepancy, however, exists in the theory that this vital material...Bibliography1. CASTLE WB: Observations on the etiological relationship of achylia gastrica to pernicious anemia. I. The effect of the administration to patients with pernicious anemia of the contents of the normal human stomach recovered after ingestion of beef muscle, Am. Jr. Med. Sci., 1929, clxxviii, 748-764. CrossrefGoogle Scholar2. CASTLETOWNSEND WBWC: Observations on the etiological relationship of achylia gastrica to pernicious anemia. II. The effect of the administration to patients with pernicious anemia of beef muscle after incubation with normal gastric juice, Am. Jr. Med. Sci., 1929, clxxviii, 764-777. CrossrefGoogle Scholar3. CASTLETOWNSENDHEATH WBWCCW: Observations on the etiological relationship of achylia gastrica to pernicious anemia. III. 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Author, Article, and Disclosure InformationAffiliations: Lincoln, Nebraska*Received for publication February 25, 1937. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDie Biochemie der VerdauungOn the Curative Effect of Pure Duodenal Secretion from Swine in Cases of Pernicious Anemia1The problem of gastrectomy and the anemiasOn the Antianemic Function of the Small Intestine1 1 July 1937Volume 11, Issue 1Page: 39-56KeywordsMucous membranesOral administrationStomach ePublished: 1 December 2008 Issue Published: 1 July 1937 PDF downloadLoading ...