GASTRIC SECRETION IN CASES OF PERNICIOUS ANEMIA
Authors: Hendrik M. Rozendaal, Richard N. Washburn
Journal: Annals of Internal Medicine (1938)

Article1 April 1938GASTRIC SECRETION IN CASES OF PERNICIOUS ANEMIAHENDRIK M. ROZENDAAL, M.D., RICHARD N. WASHBURN, M.D.HENDRIK M. ROZENDAAL, M.D.Search for more papers by this author, RICHARD N. WASHBURN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-11-10-1834 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptMany authors believe that achlorhydria is a constant finding in cases of pernicious anemia. There are, however, a number of reported cases of pernicious anemia in which free hydrochloric acid was present in the gastric contents. Alsted was able to collect 32 such cases from the literature.The cause of the achlorhydria in these cases is unknown. Faber was of the opinion that achlorhydria is always the result of atrophic gastritis which, according to him, is a constant finding in cases of pernicious anemia. Hurst, on the other hand, emphasized the constitutional factor in achlorhydria. The frequent familial occurrence of...References ALSTED G: Free hydrochloric acid in stomach in pernicious anemia, Acta med. Scandin., 1934, lxxxii, 288-299. Google Scholar FABER K: Gastritis and its consequences, 1935, Oxford University Press, London, 119 pp. Google Scholar HURST AF: Achlorhydria and achylia, and their connexion with the Addison's anaemia-subacute combined degeneration syndrome and simple (non-Addisonian) achlorhydric anemia, Quart. Jr. Med., 1932, i, 157-177. Google Scholar CONNER HM: Hereditary aspect of achlorhydria in pernicious anemia: a study of gastric acidity in 154 relatives of 109 patients having pernicious anemia, Jr. Am. Med. Assoc., 1930, xciv, 606-612. CrossrefGoogle Scholar RILEY WH: A clinical study of 264 cases of pernicious anemia with special reference to the involvement of the central nervous system, Bull. Battle Creek Sanit. and Hosp., 1923, xviii, 195-231. Google Scholar STRANDELL B: Pernicious anemia: a study of 117 cases, Acta med. Scandin. Suppl., 1931, xl, 1-124. Google Scholar LEVINELADD SAWS: Pernicious anemia: a clinical study of one hundred fifty consecutive cases with special reference to gastric anacidity, Bull. Johns Hopkins Hosp., 1921, xxxii, 255-266. Google Scholar HURST AF: A case illustrating the need of adopting prophylactic measures in individuals predisposed to Addison's anaemia, Guy's Hosp. Rep., 1930, lxxx, 244-247. Google Scholar FABERGRAM KHC: Relations between gastric achylia and simple and pernicious anemia, Arch. Int. Med., 1924, xxxiv, 658-668. CrossrefGoogle Scholar STURTEVANT M: Achlorhydria preceding pernicious anemia; report of a case of more than fourteen years' duration, Jr. Am. Med. Assoc., 1925, lxxxv, 1638-1639. CrossrefGoogle Scholar STURGIS CC: The present status of pernicious anemia: experience with 600 cases over eight years, ANN. INT. MED., 1936, x, 283-289. Google Scholar JONESBENEDICTHAMPTON CMEBAO: Variations in the gastric mucosa in pernicious anemia: gastroscopic, surgical and roentgenologic observations, Am. Jr. Med. Sci., 1935, cxc, 596-610. CrossrefGoogle Scholar VANZANTALVAREZEUSTERMANDUNNBERKSON FRWCGBHLJ: The normal range of gastric acidity from youth to old age, Arch. Int. Med., 1932, xlix, 345-359. CrossrefGoogle Scholar HEATH CW: The interrelation of pernicious anemia and idiopathic hypochromic anemia: the study of a family in which both conditions occurred both singly and combined, Am. Jr. Med. Sci., 1933, clxxxv, 365-381. CrossrefGoogle Scholar WITTS LJ: Simple achlorhydric anaemia, Guy's Hosp. Rep., 1930, lxxx, 253-296. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Rochester, Minnesota*Submitted for publication May 10, 1937. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byBlutschäden und BlutkrankheitenPernicious Anemia *Die Erkrankungen des erythrocytären SystemsAbstracts 1 April 1938Volume 11, Issue 10Page: 1834-1837KeywordsAchlorhydriaGastritisHydrochloric acidPernicious anemia ePublished: 1 December 2008 Issue Published: 1 April 1938 PDF downloadLoading ...