HORMONAL FACTORS IN HEART DISEASE: THEIR ROLE IN MYOCARDIAL HYPERTROPHY, HYPOXIA AND ELECTROLYTE IMBALANCE
Authors: W RAAB
Journal: Annals of Internal Medicine (1954)

Article1 October 1954HORMONAL FACTORS IN HEART DISEASE: THEIR ROLE IN MYOCARDIAL HYPERTROPHY, HYPOXIA AND ELECTROLYTE IMBALANCEW. RAAB, M.D., F.A.C.P.W. RAAB, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-41-4-757 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThree cardinal features of cardiac pathology—myocardial hypertrophy, myocardial structural degeneration and myocardial functional weakness—are by tradition ascribed to primarily mechanical factors, namely, increased hemodynamic resistance or decreased coronary blood flow or both. The inadequacy of such oversimplification is becoming increasingly obvious in the light of our growing comprehension of underlying myocardial metabolic anomalies, especially those induced or enhanced by the action of neurohormones (adreno-sympathogenic catecholamines) and hormones (adrenal mineralo-corticoids and thyroid hormone).1. The phenomenon of cardiac hypertrophy depends to a much lesser extent on the mechanical "burden" of increased peripheral resistance than is generally believed. This is exemplified by...Bibliography1. Beznák M: The effect of the adrenals and the pituitary on blood pressure and cardiac hypertrophy of rats, J. Physiol. 116: 219, 1952. CrossrefMedlineGoogle Scholar2. De GrandpréRaab RW: Interrelated hormonal factors in cardiac hypertrophy, Circul. Research 1: 345, 1953. CrossrefMedlineGoogle Scholar3. BeznákHajdu MJ: Ueber den Einfluss der Schilddrüse auf die Rolle der Hypophyse in den Veränderungen der Herzmasse, Schweiz. med. Wchnschr. 76: 390, 1946. 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Author, Article, and Disclosure InformationAffiliations: Burlington, Vermont*Presented at the Thirty-fifth Annual Session of the American College of Physicians, Chicago, Illinois, April 5, 1954.From the Division of Experimental Medicine, University of Vermont, College of Medicine, and the Cardiovascular Research Unit, Bishop DeGoesbriand Hospital, Burlington, Vermont. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byExperimental production of chronic cardiac aneurysm and congestive heart failure in the ratAnxiety and Angina PectorisAmine oxidase inhibitors in the treatment of angina pectorisMyokarditis und weitere MyokardiopathienThe pharmacologic limitations of diureticsElectrocardiographic and Blood-Pressure Changes during and after Biliary-Tract Surgery 1 October 1954Volume 41, Issue 4Page: 757-763KeywordsBlood flowCardiac hypertrophyCardiology and cardiovascular diseasesCardiovascular therapyCatecholaminesHemodynamicsHospital medicineHypoxiaThyroid hormones ePublished: 1 December 2008 Issue Published: 1 October 1954 PDF downloadLoading ...