tbuckley/cabot-search huggingface dataset:
SMILE A WHILE
Authors: Orville S. Walters
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Comprehensive Canadian Review of the Off-Label Use of Recombinant Activated Factor VII in Cardiac Surgery
Authors: Keyvan Karkouti, W. Scott Beattie, Ramiro Arellano, Tim Aye, Jean S. Bussieres, Jeannie L. Callum, Davy Cheng, Lee Heinrich, Blaine Kent, Trevor W.R. Lee, Charles MacAdams, C. David Mazer, Brian Muirhead, Antoine G. Rochon, Fraser D. Rubens, Corey Sawchuk, Shaohua Wang, Terrence Waters, Bill I. Wong, Terrence M. Yau
Journal: Circulation (2008)

Background— This observational study sought to identify the off-label use pattern of recombinant activated factor VII (rFVIIa) in cardiac surgery and to identify predictors of its effectiveness and risk. Methods and Results— At 18 Canadian centers, 522 nonhemophiliac cardiac surgical patients received rFVIIa during the period 2003 through 2006; data were available, and retrospectively collected, on 503 patients. The median (quartile 1, quartile 3) units of red blood cells transfused from surgery to therapy and in the 24 hours after therapy were 8 (5, 12) and 2 (1, 5), respectively ( P &lt;0.0001). Mortality rate was 32%, and mortality or major morbidity rate was 44%. These rates were within expected ranges (mortality, 27% to 35%; mortality or morbidity, 39% to 48%), which were calculated with a separate cohort of cardiac surgical patients who did not receive rFVIIa used as reference. Independent predictors of complications included instability before therapy (multiple inotropes or intra-aortic balloon pump) and increasing red blood cell units transfused before and after therapy. Variables independently associated with nonresponse included abnormal coagulation parameters and &gt;15 red blood cell units transfused before therapy. Conclusions— In Canada, rFVIIa is used primarily when standard interventions have failed to control bleeding. In this setting, rFVIIa is associated with reduced blood product transfusions and, after risk adjustment, does not appear to be associated with increased or decreased complication rates. The effectiveness of the drug may be enhanced if it is given early in the course of refractory blood loss in the setting of adequate amounts of circulating coagulation factors.
IMMUNOLOGICAL STUDIES IN RELATION TO THE SUPRARENAL GLAND
Authors: J. Marmorston-Gottesman, David Perla, Jefferson Vorzimer
Journal: The Journal of Experimental Medicine (1930)

Bilateral suprarenalectomy in rats lowers the resistance to a subsequent infection with T. lewisi. Almost 70 per cent of these rats die within an average period of 5.8 days after infection. The multiplication of the parasites in the circulating stream is not more considerable than in rats previously normal nor is the duration of the disease in the surviving rats any longer than in the normal group. Bilateral suprarenalectomy does not prevent the formation of immune substances to the parasites but appears to lower the natural resistance of the rat to the toxic effects of the protozoan infection. The acquired immunity to T. lewisi of normal rats as a result of infection is not broken down by subsequent suprarenalectomy. Unilateral nephrectomy does not affect the course of a subsequent infection with T. lewisi.
Pustulonodular Lesion on the Nose
Authors: Praveen Gundelly, Michael Young
Journal: JAMA (2014)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A BACTERIOLOGIC STUDY OF THE BLANK CARTRIDGE.
Authors: DAVID H. DOLLEY
Journal: JAMA (1905)

It appears from statistics inThe Journalof the American Medical Association, August 29, 1903, that of 392 cases of tetanus incident to accidents on the previous July 4, 363 followed wounds from the blank cartridge and the toy pistol. In other words, 92 per cent. of the tetanus cases were apparently attributable to wounds from blank cartridges. Dr. A. I. Ludlow, assistant resident surgeon at the Lakeside Hospital, succeeded in isolating<i>B. tetani</i>from the blank cartridge wounds in one out of five fatal cases of tetanus, but cultivated the<i>B. aerogenes capsulatus</i>in four. In none of these cases was there emphysema nor emphysematous gangrene of the wounds, which were routinely treated by free incision and packing with iodoform gauze. In one of these which came to autopsy I failed to isolate<i>B. tetani</i>from the wound of the hand, but obtained<i>B. aerogenes capsulatus</i>from the local
Reply to ‘Digital dermoscopy analysis and internet-based program for discrimination of pigmented skin lesion dermoscopic images’: reply from authors
Authors: P. Rubegni, M. Risulo, M. Burroni
Journal: British Journal of Dermatology (2006)

Journal Article Reply to ‘Digital dermoscopy analysis and internet‐based program for discrimination of pigmented skin lesion dermoscopic images’: reply from authors Get access P. Rubegni, P. Rubegni Department of Clinical Medicine and Immunological Sciences, Section of Dermatology, University of Siena, Policlinico ‘Le Scotte’, 53100 Siena, Italy E‐mail: rubegni@unisi.it Search for other works by this author on: Oxford Academic Google Scholar M. Risulo, M. Risulo Department of Clinical Medicine and Immunological Sciences, Section of Dermatology, University of Siena, Policlinico ‘Le Scotte’, 53100 Siena, Italy E‐mail: rubegni@unisi.it Search for other works by this author on: Oxford Academic Google Scholar M. Burroni M. Burroni Department of Clinical Medicine and Immunological Sciences, Section of Dermatology, University of Siena, Policlinico ‘Le Scotte’, 53100 Siena, Italy E‐mail: rubegni@unisi.it Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 154, Issue 3, 1 March 2006, Pages 571–572, https://doi.org/10.1111/j.1365-2133.2005.07098.x Published: 01 March 2006
Impaction of Cardiac Catheter in Coronary Vein
Authors: RAY C. ANDERSON, RICHARD L. VARCO
Journal: Circulation (1965)

A complication of right heart catheterization is described in which the tip of the catheter became impacted in a vein connecting to the coronary sinus, requiring thoracotomy and removal under direct vision. This occurred in a 2-year-old patient with an anomalous inferior vena cava with azygos continuation, and it is suggested that this anomalous course may well have contributed to the development of this complication.
NURSES' RECORDS AND HOME NURSING
Authors: Isaac A. Abt
Journal: JAMA (1927)

<h3>To the Editor:</h3> —During the last few years I have noticed that an increasing number of nurses who are sent to private homes are careless about keeping records. This applies to those who are graduates of the better nursing schools as well as to those who hold diplomas from less well known institutions. It is needless to say that a carefully kept record is an obligation which the nurse owes to the patient as well as to the physician. In days gone by, when nurses were receiving one-half the remuneration which is being given them today and were working twice as many hours, they prided themselves on the neatness and accuracy of their record sheets. Today they frequently do not keep any record at all or use a scrap of paper on which they jot down illegible notations in a haphazard and unsystematic way. In a severe case of measles-pneumonia
Injecting drug users in Edinburgh. General practitioners reluctant to prescribe.
Authors: B A Kidd, G E Ralston
Journal: BMJ (1993)

post-term delivery.'A review of 55 636 deliveries at the National Maternity Hospital, Dublin, reported an incidence of seizures of 5-4 per 1000 in those delivered after 42 weeks, compared with 0 9 per 1000 in those delivered before 42 weeks.3Cardozo states that it is important to involve the mother in decision making.Again, in her own trial 10% of the mothers refused randomisation to conservative management.2In an analysis of women's attitude towards elective delivery Roberts and Young concluded that most pregnant women are unwilling to accept conservative management of prolonged pregnancy and become more reluctant to do so by 41 weeks' gestation.4In 1990 the rate of induction among the 16 units in North West Thames region varied between 1O% and 25%.Obviously, views differ greatly, but many obstetricians will, with some justification, counsel patients with regard to elective delivery 10 to 12 days after the due date and many women will accept.
Websites fail to meet needs of disabled people
Authors: Nadeeja Koralage
Journal: BMJ (2004)

Online companies that fail to make their websites user friendly for disabled customers may have to pay out over £50 000, says the Disability Rights Commission.

The Disability Discrimination Act requires all businesses to provide equal physical access to their products and services or face the threat of prosecution—which would entail paying up to £5000 ($9000; €7500) compensation plus legal costs starting at £50 000.

The commission estimates that websites are missing out on a market of up to 12 million UK adults who cannot use the internet because of physical or other disabilities.

Disabled people are missing out, says the commission. “A lot of companies …
The effect of hypoxemic resuscitationfrom hemorrhagic shock on blood pressure restoration and on oxidative and inflammatory responses
Authors: Emmanuel E. Douzinas, Olga Livaditi, Ilias Andrianakis, Panagiotis Prigouris, Pantelis Paneris, Vassiliki Villiotou, Alex P. Betrosian
Journal: Intensive Care Medicine (2007)
Viral Respiratory Infection Rates in School-age Children With and Without Asthma
Authors: R.F. Vrtis, T.E. Pappas, M.D. Evans, K.A. Roberg, L.P. Salazar, W.M. Lee, R.F. Lemanske Jr., J.E. Gern
Journal: Journal of Allergy and Clinical Immunology (2009)
General Practitioners in Aberdeen
Authors: C. C. Lutton
Journal: BMJ (1964)

Your most recent article on " Analgesia in Labour " (13 June, p. 1555) suggests that except in dire emergency manual removal of an adherent placenta should not be carried out at home, but again that the woman should be sent to hospital.Surely this is against all current teaching.It is much better to get on and perform this operation as soon as it appears indicated.This I have done in the home a number of times, frequently with only gas and air or " trilene " (trichloroethylene) from a cyprane inhaler, aided by local anaes- thetic, and without causing the patient any distress.To move a shocked patient to hos- pital is surely most dangerous.-Iam, etc., Norwich.
THE EFFECT OF DIET ON THE DEVELOPMENT AND EXTENSION OF CARIES IN THE TEETH OF CHILDREN: (Preliminary Note.)
Authors: M. Mellanby, C. L. Pattison, J. W. Proud
Journal: BMJ (1924)

t ThDICA Jou^= nervous energy tllrough the phreniio wi]l diminish and lead to movements of the vocal cord in which the excursions will be equal to, and not greater than, those of the vocal cord on the opposite or niormiial side?Another question also requires an answer: When the vocal cord is movinig normiially through nervous impulses conveyed to it through the phrenic, will the patient be able to phonate?This is the question asked by Sir FrederickMott.The answer can hardly be decided by experiment on the monkey: operation on man will give the reply.This will be thle decisive experiment.The conlclusion, therefore, appears to be, that for the cure of recurrent laryngeal palsy and the attainment of normal movement of the vocal cord in tranquil respiration, anastomosis with the vagus or the descendens noni must be rejected, anid some form of anastolmiosis should be carried out with the trunk or with one of the roots of the phrenic nerve.
Enzyme Typing of Malaria Parasites
Authors: R. Carter, A. Voller
Journal: BMJ (1973)

Analysis of various isolates of Plasmodium falciparum from East and West Africa and from South-east Asia showed that some of the parasite enzymes can exist in more than one electrophoretic form. At least one form of each enzyme was common to parasites from all three regions. The enzyme forms could be used to differentiate morphologically indistinguishable samples of P. falciparum.
Serum interleukin-13 levels are increased in patients with Stevens–Johnson syndrome/ toxic epidermal necrolysis but not in those with erythema multiforme
Authors: P. Quaglino, M. Caproni, S. Osella-Abate, D. Torchia, A. Comessatti, E. Del Bianco, E. Antiga, A. Frezzolini, D. Schena, A. Marzano, C. De Simone, A. Parodi, P. Fabbri, M.G. Bernengo
Journal: British Journal of Dermatology (2007)
Phosphodiesterase Type-5 Inhibitors and the Reemerging HIV Epidemic
Authors: Todd Hulgan
Journal: JAMA (2008)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
AN UNUSUAL CASE OF PROLONGED COMA IN HYPOGLYCEMIC SHOCK TREATMENT
Authors: L. D. PROCTOR, N. L. EASTON
Journal: American Journal of Psychiatry (1942)

A case of prolonged coma has been presented, the blood sugar findings discussed, and several of the various mechanisms set forth that could contribute to the abnormalities observed in these findings. The relationship of the blood sugar findings to the state of consciousness has been considered. The recovery of this patient would make one hopeful for the outcome of even the most severe type of prolonged coma, following insulin shock therapy.
The Crosstalk of mTOR/S6K1 and Hedgehog Pathways
Authors: Yan Wang, Qingqing Ding, Chia-Jui Yen, Weiya Xia, Julie G. Izzo, Jing-Yu Lang, Chia-Wei Li, Jennifer L. Hsu, Stephanie A. Miller, Xuemei Wang, Dung-Fang Lee, Jung-Mao Hsu, Longfei Huo, Adam M. LaBaff, Dongping Liu, Tzu-Hsuan Huang, Chien-Chen Lai, Fuu-Jen Tsai, Wei-Chao Chang, Chung-Hsuan Chen, Tsung-Teh Wu, Navtej S. Buttar, Kenneth K. Wang, Yun Wu, Huamin Wang, Jaffer Ajani, Mien-Chie Hung
Journal: Cancer Cell (2012)
Major Teaching Hospitals Defying Darwin
Authors: Lisa I. Iezzoni
Journal: JAMA (1997)

"The increase of every creature is constantly being checked by unperceived hostile agencies; and... these same unperceived agencies are amply sufficient to cause rarity, and finally extinction," wrote Charles Darwin in<i>The Origin of Species.</i><sup>1</sup>Today's competitive health care environment is pointedly Darwinian, but its "hostile agencies" are amply apparent. An unspoken, subversive subtext anticipates "survival of the fittest"—we all know the fate of the dinosaurs. Nowadays, as health policy experts muse about which health care institutions risk extinction, major teaching hospitals are not infrequently called dinosaurs. Underlying this speculation is the assumption that price, virtually exclusively, drives hospital competition. For many reasons, most major teaching hospitals are undeniably costlier than nonteaching facilities.<sup>2</sup>But what about broader societal contributions, such as education and research, and what about quality of care? See also p 485. In the natural world, wily ways—speedy and clever responses to external threats—provide primal survival
Habituation to Ethinamate
Authors: Everett H. Ellinwood, John A. Ewing, P. C. S. Hoaken
Journal: New England Journal of Medicine (1962)

ETHINAMATE, 1-ethinyl-cyclohexyl-carbamate, is one of the newer nonbarbiturate sedative hypnotics. The Journal reported on its use in 1957, pointing out that it can be utilized even in the presence of severe liver or renal damage and that "in a few cases" it had been suspected of producing addiction: "The data, however, are not definite, and further observation is necessary in this regard."1 The same article stated that the fatal dose was unknown but that as much as 28 gm. had not caused death. Since that time a report of a death in this hospital from ingestion of at least 15 . . .
Coronary Atherosclerosis Is Associated With Macrophage Polarization in Epicardial Adipose Tissue
Authors: Yoichiro Hirata, Minoru Tabata, Hirotsugu Kurobe, Tatsuo Motoki, Masashi Akaike, Chika Nishio, Mayuko Higashida, Hiroaki Mikasa, Yutaka Nakaya, Shuichiro Takanashi, Takashi Igarashi, Tetsuya Kitagawa, Masataka Sata
Journal: Journal of the American College of Cardiology (2011)
Upper Airway Collapsibility and Cephalometric Variables in Patients with Obstructive Sleep Apnea
Authors: EMILIA SFORZA, WILLIAM BACON, THOMAS WEISS, ANNE THIBAULT, CHRISTOPHE PETIAU, JEAN KRIEGER
Journal: American Journal of Respiratory and Critical Care Medicine (2000)

Increased pharyngeal collapsibility and abnormal anatomic structures have been postulated to contribute to the pathophysiology of obstructive sleep apnea (OSA) syndrome. It is unclear whether the abnormal craniofacial and soft tissue features may affect the pharyngeal collapsibility and contribute to the apnea density. In the present study we examine the relationship between pharyngeal collapsibility and cephalometric variables in a group of 57 male OSA patients. Pharyngeal collapsibility was measured during the night of nasal continuous positive airway pressure (nCPAP) titration by analyzing the pressure-flow relationship. Pharyngeal critical pressure (Pcrit) was calculated as the extrapolated pressure at zero flow. The patients, age 52.0 +/- 9.0 yr, had an average apnea-hypopnea index (AHI) of 72.6 +/- 31.8 and a mean Pcrit of 2.4 +/- 1.0 cm H(2)O. A significant correlation was found between Pcrit and the soft palate length (SPl) (r = 0.27, p = 0.04), the distance from the hyoid bone to the posterior pharyngeal wall (H-Ph) (r = 0. 29, p = 0.03), and the distance from the hyoid bone to posterior nasal space (H-Pns) (r = 0.32, p = 0.02). While in obese patients Pcrit was related to SPl and neck circumference, the distance of the hyoid bone to the mandibular plane (H-MP) affected Pcrit in nonobese patients. Our results show that both pharyngeal soft tissue abnormalities and the lower position of the hyoid bone affect Pcrit in OSA patients, suggesting that an anatomic narrowing contributes to the upper airway collapsibility.
TWO CASES OF ACUTE DILATATION OF THE STOMACH FOLLOWING ABDOMINAL OPERATION.
Authors: STAFFORD B. SMITH
Journal: JAMA (1907)

<h3>Case 1.</h3> —Miss A., aged 28, entered the hospital with a diagnosis of acute appendicitis. The abdomen was opened and an apparently normal appendix was removed. The wound was sealed. Till the tenth day the patient did well, but had very little appetite and was constipated; temperature normal. <h3>Postoperative History.</h3> —On the eleventh day following the operation the patient felt some distress in the epigastrium, vomited copiously and was much relieved. Later in the day, I was notified that she was pulseless. A few minutes later, I counted the pulse in the carotid and found it 200. The patient was breathing a little hard and complained of slight abdominal pain. I looked at the wound and found it in excellent condition. The abdomen, however, was considerably distended and generally tympanitic. Stimulants were given hypodermically and warmth was applied to the cold extremities. While I was at the bedside, the patient
Spironolactone inhibits the transcardiac extraction of aldosterone in patients with congestive heart failure
Authors: Takayoshi Tsutamoto, Atsuyuki Wada, Keiko Maeda, Naoko Mabuchi, Masaru Hayashi, Takashi Tsutsui, Masato Ohnishi, Masahide Sawaki, Masanori Fujii, Takehiro Matsumoto, Hajime Horie, Yoshihisa Sugimoto, Masahiko Kinoshita
Journal: Journal of the American College of Cardiology (2000)