SARCOIDOSIS WITH MARKED HEPATOSPLENOMEGALY AND JAUNDICE: A CASE REPORT WITH BIOPSY FINDINGS
Authors: A E DAGRADI, N SOLLOD, J H FRIEDLANDER
Journal: Annals of Internal Medicine (1952)

Case Reports1 May 1952SARCOIDOSIS WITH MARKED HEPATOSPLENOMEGALY AND JAUNDICE: A CASE REPORT WITH BIOPSY FINDINGSA. E. DAGRADI, M.D., N. SOLLOD, M.D., J. H. FRIEDLANDER, M.D.A. E. DAGRADI, M.D.Search for more papers by this author, N. SOLLOD, M.D.Search for more papers by this author, J. H. FRIEDLANDER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-36-5-1317 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSince the original description by Boeck1 in 1899 of the histologic characteristics of the disease sarcoidosis, and the demonstration by Schaumann in 1914 that it can become generalized, with a particular predilection for the lymphohematopoietic system, an extensive literature has appeared on the subject. This has been reviewed recently in some detail by Freiman.2Hepatic and/or splenic enlargement has been noted to occur clinically in a certain number of cases of Boeck's sarcoid, the incidence of liver enlargement being perhaps slightly less than that of splenic enlargement. The study of postmortem3, 4and of biopsy material5, 6, 7obtained from...Bibliography1. Boeck C: Multiple benign sarcoid of the skin, J. Cut. and Genito-Urinary Dis. 17: 543, 1899. Google Scholar2. Freiman DG: Sarcoidosis, New England J. Med. 239: 664-669 (Oct. 28) 1948; 239: 709-716 (Nov. 4) 1948; 239: 743-749 (Nov. 11) 1948. CrossrefMedlineGoogle Scholar3. RubinPinner EHM: Sarcoidosis, Am. Rev. Tuberc. 49: 146-169 (Feb.) 1944. Google Scholar4. Nickerson SA: Boeck's sarcoid, Arch. Path. 24: 19 (July) 1937. Google Scholar5. VolwilerJones WCM: Diagnostic and therapeutic value of liver biopsies, New England J. Med. 237: 651-656, 1947. CrossrefMedlineGoogle Scholar6. Van BeekHaex CAJ: Aspiration-biopsy of liver in mononucleosis infections and in Besnier-Boeck Schaumann's disease, Acta med. Scandinav. 113: 125, 1943. CrossrefGoogle Scholar7. Van Buchem FS: On morbid conditions of liver and diagnosis of disease of Besnier, Boeck, Schaumann, Acta med. Scandinav. 124: 168-184, 1946. CrossrefGoogle Scholar8. Harrell GT: Generalized sarcoidosis of Boeck, Arch. Int. Med. 65: 1003-1034, 1940. CrossrefGoogle Scholar9. LongcopePierson WTJW: Sarcoidosis, Bull. Johns Hopkins Hosp. 60: 223-296, 1937. Google Scholar10. CurtisGrekin ACRH: Sarcoidosis. III. A review, M. Clin. North America 33: 31-54, 1949. CrossrefMedlineGoogle Scholar11. Goeckerman WH: Sarcoids and related lesions, Arch. Dermat. and Syph. 18: 237-262 (Aug.) 1928. CrossrefGoogle Scholar12. Longcope WT: Sarcoidosis, J. A. M. A. 117: 1321 (Oct. 18) 1941. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Northport, New York*Received for publication April 10, 1950.From The Medical Service, Northport V. A. Hospital.Published with permission of the chief medical director, Department of Medicine and Surgery, Veterans Administration, who does not assume responsibility for the opinions expressed or conclusions drawn by the authors. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySarkoidoseChronic intrahepatic cholestasis of sarcoidosisMassive sarcoidosis of the liverJaundice Associated with Hepatic Sarcoidosis in a Child, Report of a CašeProgressive hepatic decompensation with terminal hepatic coma in sarcoidosisLeber und intrahepatische Gallenwege, PfortaderkreislaufHepatic sarcoidosis with portal hypertensionPortal Hypertension In Hepatic SarcoidosisPortal hypertension and bleeding esophageal varices secondary to sarcoidosis of the liverMorbus BoeckMorbus BoeckSARCOIDOSIS—HEPATIC INVOLVEMENT: PRESENTATION OF A CASE WITH FATAL LIVER INVOLVEMENT, INCLUDING AUTOPSY FINDINGS AND REVIEW OF THE EVIDENCE FOR SARCOID INVOLVEMENT OF THE LIVER AS FOUND IN THE LITERATURE*JOHN H. BRANSON, M.D., JAMES H. PARK, M.D. 1 May 1952Volume 36, Issue 5Page: 1317-1323KeywordsBiopsyHepatosplenomegalyLiverMedical servicesSarcoidosisSurgery ePublished: 1 December 2008 Issue Published: 1 May 1952 PDF downloadLoading ...