OBESITY AND ITS TREATMENT, WITH PARTICULAR REFERENCE TO THE USE OF ANOREXIGENIC COMPOUNDS
Authors: R H WILLIAMS, W H DAUGHALAY
Journal: Annals of Internal Medicine (1948)

Article1 September 1948OBESITY AND ITS TREATMENT, WITH PARTICULAR REFERENCE TO THE USE OF ANOREXIGENIC COMPOUNDSROBERT H. WILLIAMS, M.D., F.A.C.P., WILLIAM H. DAUGHADAY, M.D., WALTER F. ROGERS JR., M.D., SAMUEL P. ASPER JR., M.D., BEVERLY T. TOWERY, M.D.ROBERT H. WILLIAMS, M.D., F.A.C.P.Search for more papers by this author, WILLIAM H. DAUGHADAY, M.D.Search for more papers by this author, WALTER F. ROGERS JR., M.D.Search for more papers by this author, SAMUEL P. ASPER JR., M.D.Search for more papers by this author, BEVERLY T. TOWERY, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-29-3-510 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn spite of the frequent enlightening discussions in social and scientific circles on factors contributing to the development of obesity and on the treatment of this condition, there continues to be a vast number of markedly obese individuals. The deleterious effects produced by this condition, directly or indirectly, are much greater than seems to be generally recognized. In addition to the social and occupational handicaps and associated mental distress which obesity causes, it predisposes to the development of cardiovascular diseases and diabetes mellitus. Marked obesity exerts a pronounced effect on life expectancy. For example, Dublin and Lotka1found that individuals...Bibliography1. DUBLINLOTKA LIAJ: Length of life, 1936, The Roland Press Co., New York. Google Scholar2. NEWBURGH LH: Obesity, Arch. Int. Med., 1942, lxx, 1033-1096. CrossrefGoogle Scholar3. EVANS FA: Obesity, from Diseases of metabolism, edited by G. G. Duncan, Ch. X, 1947, W. B. Saunders Co., Philadelphia. Google Scholar4. WILDER RM: Regulation of the weight of the body, Internat. Clin., 1932, i (Series 42), 30-41. Google Scholar5. DUBLINMARKS LIHH: Mortality of women according to build, The Assoc. of Life Ins. Med. Directors of Am., Oct. 20, 1938. Google Scholar6. RANSONFISHERINGRAM SWCWR: Adiposity and diabetes mellitus in monkey with hypothalamic lesions, Endocrinology, 1938, xxiii, 175-181. HETHRINGTON, A. W., and RANSON, S. W.: Experimental hypothalamico-hypophyseal obesity in rat, Proc. Soc. Exper. Biol. and Med., 1939, xli, 465-466. CrossrefGoogle Scholar7. BROBECKTEPPERMANLONG JRJCN: Effect of experimental obesity upon carbohydrate metabolism, Yale Jr. Biol. and Med., 1942-43, xv, 831-853. Google Scholar8. WILLIAMS RH: Unpublished data. Google Scholar9. KEPLER EJ: Symposium on the synthesis and biological action of the adrenal hormone dehydrocorticosterone, March 11, 1946, Atlantic City, New Jersey. Google Scholar10. HARTMANBROWNELLTHATCHER FAKAJS: A new hormone of the adrenal cortex, Jr. Clin. Endocrinol., 1947, vii, 461-462. Google Scholar11. STRONGMCCLUGAGEBROWNLEE JMHBMA: The nitrogen balance during dietary correction of obesity, Am. Jr. Med. Sci., 1931, clxxxi, 336-349. CrossrefGoogle Scholar12. HARRISIVYSEARLE SCACLM: Loss of weight, Jr. Am. Med. Assoc., 1947, cxxxiv, 1468-1474. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication November 18, 1947.From the Thorndike Memorial Laboratory, Second and Fourth Medical Services (Harvard), Boston City Hospital, and the Department of Medicine, Harvard Medical School, Boston, Massachusetts.†Now at Department of Medicine, University of Washington, Seattle, Washington. 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CHARLES FREED, M.D., MEYER MIZEL, M.D.THE TREATMENT OF OBESITY WITH AN ANOREXIGENIC DRUG*ELLA ROBERTS, M.D., F.A.C.P.OBESITY IN DIABETES: A STUDY OF THERAPY WITH ANOREXIGENIC DRUGS*KERMIT E. OSSERMAN, M.D., HENRY DOLGER, M.D., F.A.C.P.Evaluation of the effect of d-amphetamine sulfate in the treatment of obesity in childrenHypertensionThe Pharmacology and Clinical Use of the Sympathomimetic Drugs in AnesthesiologyThe Management of Obesity in Childhood 1 September 1948Volume 29, Issue 3Page: 510-532KeywordsCardiovascular diseasesDiabetes mellitusHospital medicineLife expectancyMedical servicesObesityOverweightResearch laboratories ePublished: 1 December 2008 Issue Published: 1 September 1948 PDF downloadLoading ...