XANTHOMATOUS BILIARY CIRRHOSIS SECONDARY TO CARCINOMA OF THE EXTRAHEPATIC BILE DUCTS
Authors: L J STUTMAN, R C BOZIAN
Journal: Annals of Internal Medicine (1960)

Case Reports1 January 1960XANTHOMATOUS BILIARY CIRRHOSIS SECONDARY TO CARCINOMA OF THE EXTRAHEPATIC BILE DUCTSLEONARD J. STUTMAN, RICHARD C. BOZIANLEONARD J. STUTMANSearch for more papers by this author, RICHARD C. BOZIANSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-52-1-229 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptWe have found but three reported cases of biliary3, 4, 5 cirrhosis with generalized xanthomatosis secondary to carcinoma of the biliary tree. Thannhauser and Magendantz in 19381 and Thannhauser in 19402 defined the syndrome as: (1) skin xanthomata of plain and tuberous variety; (2) obstructive type of jaundice of at least one year's duration; (3) enlarged liver and spleen; (4) extremely high values for total cholesterol as well as lecithin; (5) blood serum which was transparent and not creamy, even though the cholesterol was high; (6) low to normal values for neutral fat.We are reporting an additional case secondary...Bibliography1. ThannhauserMagendantz SJH: The different clinical groups of xanthomatous diseases; a clinical physiological study of 22 cases, Ann. Int. Med. 11: 1662, 1938. LinkGoogle Scholar2. Thannhauser SJ: Lipoidoses, 1940, Oxford University Press, New York. Google Scholar3. Pye-Smith PH: Xanthelasma, Guy's Hosp. Rep. 22: 93, 1877. Google Scholar4. WeidmanBoston FDLN: Generalized xanthoma tuberosum with xanthomatous changes in fresh scars of intercurrent zoster; adenocarcinoma of ampulla of Vater at necropsy, Arch. Int. Med. 59: 793, 1937. CrossrefGoogle Scholar5. AhrensPayneKunkelEisenmengerBlondheim EHMAHGWJSH: Primary biliary cirrhosis, Medicine 29: 299-364 (Dec.) 1950. CrossrefMedlineGoogle Scholar6. ShayHarris HH: Changing concepts of xanthomatous biliary cirrhosis, Am. J. M. Sc. 223: 286-300, 1952. CrossrefMedlineGoogle Scholar7. MacMahonThannhauser HESJ: Xanthomatous biliary cirrhosis (a clinical syndrome), Ann. Int. Med. 30: 121-179 (Jan.) 1949. LinkGoogle Scholar8. MillerPollard WRHM: Xanthomatous biliary cirrhosis, Ann. Int. Med. 38: 845-851, 1953. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication February 6, 1959.From the New York University Post-Graduate Medical School and the Fourth (New York University) Medical Division, Bellevue Hospital, New York, N. Y.Requests for reprints should be addressed to Leonard J. Stutman, M.D., Institute of Physical Medicine and Rehabilitation, New York University-Bellevue Medical Center, 400 East Thirty-fourth Street, New York 16, N. Y. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byExtrahepatic Cholangiocarcinoma: Carcinoma of the Middle and Distal Common Bile Duct (Middle and Lower Bile Duct Carcinomas)Extrahepatic Cholangiocarcinoma: Carcinoma of the Middle and Distal Common Bile Duct (Middle and Lower Bile Duct Carcinomas) 1 January 1960Volume 52, Issue 1Page: 229-234KeywordsAdenocarcinomaBile ductsBiliary systemBloodCholesterolCirrhosisFatsHepatomegalyHypercholesterolemiaSpleen ePublished: 1 December 2008 Issue Published: 1 January 1960 PDF downloadLoading ...