INTERSEXUALITY OR PSEUDO-HERMAPHRODISM
Authors: A. C. Ivy, R. R. Greene, M. W. Burrill
Journal: Annals of Internal Medicine (1939)

Article1 July 1939INTERSEXUALITY OR PSEUDO-HERMAPHRODISMA. C. IVY, PH.D., M.D., F.A.C.P., R. R. GREENE, M.S., M.D., M. W. BURRILL, PH.D.A. C. IVY, PH.D., M.D., F.A.C.P.Search for more papers by this author, R. R. GREENE, M.S., M.D.Search for more papers by this author, M. W. BURRILL, PH.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-13-1-68 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIt is generally assumed that the sex of an individual is determined at its inception by specific genetic factors, but in order for the genetically determined sex to be expressed anatomically, certain conditions must prevail during the developmental period. The sex-hormone complex which plays an important rôle in the development of sexual structures is normally in accord with the genetic factors so that development proceeds toward the expression of the genetically determined sex. However, alteration in the sex-hormone complex can result in modification of the normal course of sexual differentiation so that abnormal conditions may arise.The anatomical expression of...References1. WILLIERGALLAGHERKOCH BHTFFC: Sex-modification in the chick embryo resulting from injections of male and female hormones, Proc. Soc. Nat. Acad. Sci., 1935, xxi, 625. CrossrefGoogle Scholar2. WILLIERGALLAGHERKOCH BHTFFC: The modification of sex development in the chick embryo by male and female hormones, Physiol. Zool., 1937, x, 101. CrossrefGoogle Scholar3. WILLIER BH: The action of synthetic male hormones upon the differentiation of sex in the chick embryo, Science, 1937, lxxxvi, 409. Google Scholar4. 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Author, Article, and Disclosure InformationAffiliations: Chicago, Illinois*Read at the New Orleans meeting of the American College of Physicians, March 31, 1939.From the Department of Physiology and Pharmacology, Northwestern University Medical School, Chicago.The crystalline sex hormones used in these experiments were furnished through the courtesy of Dr. Ernst Oppenheimer of Ciba Pharmaceutical Corporation.Part of the expenses of this experimental work were defrayed by a grant from the Josiah Macy, Jr. Foundation. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySexual differentiation in the opossum after early gonadectomy 1 July 1939Volume 13, Issue 1Page: 68-80KeywordsGenetic determinismPharmacologySex hormones Issue Published: 1 July 1939 PDF downloadLoading ...