Misunderstanding Concerning the Proper Clinical Use of Oxygen
Authors: THOMAS L. PETTY
Journal: Annals of Internal Medicine (1969)

Editorial Notes1 March 1969Misunderstanding Concerning the Proper Clinical Use of OxygenTHOMAS L. PETTY, M.D.THOMAS L. PETTY, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-70-3-645 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlthough oxygen has been available in clinical medicine for many years, its use, particularly in chronic airway obstruction, has remained controversial, even in patients with acute or chronic respiratory insufficiency and hypoxemia. This attitude remains at a time when we have improved knowledge concerning precision of oxygen administration in patients with acute respiratory failure (1, 2) and evidence of the safety and efficacy of continuous oxygen for prolonged periods in ambulatory patients (3, 4).In chronic airway obstruction (emphysema and chronic bronchitis) acute exacerbations of infection frequently lead to acute uncompensated respiratory failure, often with profound hypoxemia with or without...References1. FLENLEY DC: The rationale of oxygen therapy. Lancet 1: 270, 1967. CrossrefMedlineGoogle Scholar2. CHERNIACKHAKIMPOUR RMK: The rational use of oxygen in respiratory insufficiency. JAMA 199: 178, 1967. CrossrefMedlineGoogle Scholar3. LEVINEBIGELOWHAMSTRABECKWITTMITCHELLNETTSTEPHENPETTY BEDBRPHJRSLNTATL: The role of long-term continuous oxygen administration in patients with chronic airway obstruction with hypoxemia. Ann. Intern. Med. 66: 639, 1967. LinkGoogle Scholar4. PETTYFINIGAN TLMM: Clinical evaluation of prolonged ambulatory oxygen therapy in chronic airway obstruction. Amer. J. Med. 45: 242, 1968. CrossrefMedlineGoogle Scholar5. EMMANUELSMITHBRISCOE GEWMWA: The effect of intermittant positive pressure breathing and voluntary hyperventilation upon the distribution of ventilation and pulmonary blood flow to the lungs in chronic obstructive lung disease. J. Clin. Invest. 45: 1221, 1966. CrossrefMedlineGoogle Scholar6. CAMPBELL EJ: A method of controlled oxygen administration which reduces the risk of carbon dioxide retention. Lancet 1: 12, 1960. CrossrefGoogle Scholar7. SMITHSTONEMUCHENHEIM JPRWC: Acute respiratory failure in chronic lung disease (observations on controlled oxygen therapy) Amer. Rev. Resp. Dis. 97: 791, 1968. MedlineGoogle Scholar8. ELDRIDGEGHERMAN FC: Studies of oxygen administration in respiratory failure. Ann. Intern. Med. 68: 569, 1968. LinkGoogle Scholar9. BIGELOWPETTYLEVINEFILLEYFINIGAN DBTLBEGFMM: The effect of oxygen breathing on arterial blood gases in patients with chronic airway obstruction living at 5, 200 feet. Amer. Rev. Resp. Dis. 96: 28, 1967. MedlineGoogle Scholar10. FISHER AB: Oxygen poisoning, a disease of medical progress. Inhal. Ther. 13: 67, 1968. Google Scholar11. Editorial: More hazards of oxygen. New Eng. J. Med. 279: 379, 1968. CrossrefMedlineGoogle Scholar12. COTESGILSON JEJC: Effect of oxygen on exercise ability in chronic respiratory insufficiency. Lancet 1: 872, 1956. CrossrefGoogle Scholar13. BARACH AL: Regulated oxygen therapy and adaptive values of CO2 retention in patients with pulmonary emphysema. Ann. Allerg. 23: 361, 1965. MedlineGoogle Scholar14. ABRAHAMCOLEBISHOP ASRBJM: Reversal of pulmonary hypertension by prolonged oxygen administration to patients with chronic bronchitis. Circ. Res. 23: 147, 1968. CrossrefMedlineGoogle Scholar15. CHAMBERLAINMILLARD DAFJ: The treatment of polycythemia secondary to hypoxic lung disease by continuous oxygen administration. Quart. J. Med. 32: 341, 1963. MedlineGoogle Scholar16. ASHBAUGHBIGELOWPETTYLEVINE DGDBTLBE: Acute respiratory distress in adults. Lancet 2: 319, 1967. CrossrefMedlineGoogle Scholar17. ASHBAUGHPETTYBIGELOWHARRIS DGTLDBTM: Continuous positive pressure breathing (CPPB) in adult respiratory distress syndrome. J. Cardiac Thoracic Surg. 57: 33, 1969. CrossrefGoogle Scholar18. WINTERGAPTAMICHALSKILAMPHIER PMRKAEH: Modifications of hyperbasic oxygen toxicity by experimental venous admixture. J. Appl. Physiol. 23: 954, 1967. CrossrefMedlineGoogle Scholar19. HARRISGRAYPETTYMUELLER TMMTLR: Monitoring inspired oxygen pressures during mechanical ventilation. JAMA 206: 2885, 1968. CrossrefMedlineGoogle Scholar20. THOMASMALCRONASHILLINFORD MRJP: Hemodynamic effects of oxygen in patients with acute myocardial infarction. Brit. Heart J. 27: 401, 1965. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: THOMAS L. PETTY, M.D.Affiliations: University of Colorado Medical Center Denver, Colo. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byUses and misuses of oxygen in hospitalized patientsChronic Oxygen TherapyNeed for 100 Per Cent Oxygen TherapyLong-Term Continuous Oxygen Therapy in Chronic Airway Obstruction Mortality in Relationship to Cor Pulmonale, Hypoxia, and HypercapniaTHOMAS A. NEFF, M.D., THOMAS L. PETTY, M.D.OXYGEN THERAPYRICHARD W. HYDE, M.D., ARON B. FISHER, M.D. 1 March 1969Volume 70, Issue 3Page: 645-646KeywordsChronic bronchitisEmphysemaHypoxiaOxygenRespiratory failureSafetyUpper respiratory tract infections ePublished: 1 December 2008 Issue Published: 1 March 1969 PDF downloadLoading ...