THE PROLONGED WATERHOUSE-FRIDERICHSEN SYNDROME WITH RENAL AND MYOCARDIAL INSUFFICIENCY
Authors: Stuart H. Walker, Robert L. Cavenaugh, Harold Williams
Journal: Annals of Internal Medicine (1953)

Case Reports1 March 1953THE PROLONGED WATERHOUSE-FRIDERICHSEN SYNDROME WITH RENAL AND MYOCARDIAL INSUFFICIENCYSTUART H. WALKER, ROBERT L. CAVENAUGH, HAROLD WILLIAMSSTUART H. WALKERSearch for more papers by this author, ROBERT L. CAVENAUGHSearch for more papers by this author, HAROLD WILLIAMSSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-38-3-610 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptWith the availability of potent adrenal cortical replacement therapy, cortisone, and highly effective chemotherapeutic agents against the meningococcus, sulfadiazine and the broad spectrum antibiotics, a marked reduction in the mortality of the Waterhouse-Friderichsen syndrome was to be expected. However, it appears from the experience reported herein and that of others1that we have but escaped the Scylla of fulminating peripheral vascular collapse to run upon the Charybdis of renal and myocardial insufficiency. Marangoni and D'Agati1have emphasized the constant presence of renal insufficiency in the Waterhouse-Friderichsen syndrome, and demonstrated its second stage, prolonged anuria and azotemia following the resolution of...Bibliography1. MarangoniD'Agati BAVC: Hepatorenal failure in Waterhouse-Friderichsen syndrome; clinicopathologic observations in two cases with prolonged survival periods, Am. J. M. Sc. 207: 385, 1944. CrossrefGoogle Scholar2. Martland HS: Fulminating meningococcic infection with bilateral massive adrenal hemorrhage (the Waterhouse-Friderichsen syndrome), Arch. Path. 37: 147, 1944. Google Scholar3. SelyeStone HH: On the experimental morphology of the adrenal cortex, 1950, Charles C Thomas, Publisher, Springfield, Ill. Google Scholar4. 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CAVENAUGH; HAROLD WILLIAMS*Received for publication August 2, 1952.From the Pediatric and Infectious Disease Section, William Beaumont Army Hospital, Fort Bliss, Texas. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAn appraisal of fulminant meningococcemia with reference to the shwartzman phenomenon 1 March 1953Volume 38, Issue 3 Page: 610-619 Keywords Antibiotics Chemotherapeutic agents Infectious diseases Mortality Neisseria meningitidis Patients Research laboratories ePublished: 1 December 2008 Issue Published: 1 March 1953 PDF downloadLoading ...