MACROCYTIC ANEMIA, OTHER THAN PERNICIOUS ANEMIA, ASSOCIATED WITH LESIONS OF THE GASTROINTESTINAL TRACT
Authors: Cyrus C. Sturgis, S. Milton Goldhamer
Journal: Annals of Internal Medicine (1939)

Article1 February 1939MACROCYTIC ANEMIA, OTHER THAN PERNICIOUS ANEMIA, ASSOCIATED WITH LESIONS OF THE GASTROINTESTINAL TRACTCYRUS C. STURGIS, M.D., F.A.C.P., S. MILTON GOLDHAMER, M.D.CYRUS C. STURGIS, M.D., F.A.C.P.Search for more papers by this author, S. MILTON GOLDHAMER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-12-8-1245 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptA macrocytic anemia may be defined as an anemia in which there is an increase in the number of red blood cells of the circulating blood having a diameter greater than 7.5 microns, and a mean corpuscular volume which exceeds 96 cubic microns. In such an anemia the color index usually is one or higher. It is generally considered to be due to defective blood formation and is frequently controlled by anti-pernicious anemia medication but is not ordinarily benefited by iron therapy.An anemia of this type is characteristically found in true Addisonian pernicious anemia, in the so-called "tropical anemia"...Bibliography1. CASTLE WB: Observation on the etiologic relationship of achylia gastrica to pernicious anemia. I. The effect of the administration to patients with pernicious anemia of the contents of the normal human stomach recovered after the ingestion of beef muscle, Am. Jr. Med. Sci., 1929, clxxviii, 746. Google Scholar2. CASTLETOWNSEND WBWC: Observation on the etiologic relationship of achylia gastrica to pernicious anemia. II. The effect of the administration to patients with pernicious anemia of beef muscle after incubation with normal human gastric juice, Am. Jr. Med. Sci., 1929, clxxviii, 764. CrossrefGoogle Scholar3. 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DAVIDSON LS: Autolysed yeast products in the treatment of anemia, Brit. Med. Jr., 1933, ii, 481. CrossrefGoogle Scholar27. RUSSELL HK: Hematological response of Addisonian pernicious anemia to brewer's yeast, ANN. INT. MED., 1934, vii, 1398. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Ann Arbor, Michigan*Delivered before the American College of Physicians, New York City, April 7, 1938.From the Thomas Henry Simpson Memorial Institute for Medical Research, University of Michigan. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPostgastrectomy problemsDELAYED DEVELOPMENT OF PERNICIOUS ANEMIA FOLLOWING GASTRECTOMY; HIGH FAMILIAL INCIDENCE OF CANCER: AN ILLUSTRATIVE CASE*MARTIN L. CHARLES, M.D., LOUIS J. VORHAUS, M.D.Undesirable Sequelae of Subtotal Gastric ResectionAbsorption of Radioactive Vitamin B12 after Total GastrectomyAchylia gastrica: Keystone in the development and eradication of macrocytic achylic anemia (Pernicious anemia, Addison-Biermer)Experimental studies on production of pernicious anemia by operation on the digestive tract1Die Erkrankungen des erythrocytären SystemsClinical evaluation of GastritisThe problem of gastrectomy and the anemias 1 February 1939Volume 12, Issue 8Page: 1245-1262KeywordsAnemiaBloodBlood cellsBlood volumeGastrointestinal tractLesionsMean corpuscular volumePernicious anemiaRed blood cells ePublished: 1 December 2008 Issue Published: 1 February 1939 PDF downloadLoading ...