INTRAVENOUS VACCINE THERAPY IN CHRONIC ARTHRITIS
Authors: William B. Rawls, B. J. Gruskin, A. Ressa
Journal: Annals of Internal Medicine (1933)

Article1 November 1933INTRAVENOUS VACCINE THERAPY IN CHRONIC ARTHRITISWILLIAM B. RAWLS, M.D., F.A.C.P., B. J. GRUSKIN, M.D., A. RESSA, M.D.WILLIAM B. RAWLS, M.D., F.A.C.P.Search for more papers by this author, B. J. GRUSKIN, M.D.Search for more papers by this author, A. RESSA, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-7-5-566 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptMuch attention has been focused on the subject of chronic arthritis during the past few years and a survey of the literature shows an increasing belief in the streptococcal etiology of this condition.1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11Many points of similarity have been noted between chronic arthritis, especially the so-called rheumatoid type, and rheumatic fever.12Menzer,13in 1902, in an endeavor to explain the peculiar action of his serum in rheumatic fever, advanced a theory which, in many respects, resembles the modern concept of allergy. More recently, Swift14, 15, 16, 17and Zinsser18, 19...References1. POYNTONPAYNE FJA: Researches on rheumatism, 1913, Macmillan Company, London. Google Scholar2. ROSENOW EC: Etiology of arthritis deformans; preliminary note, Jr. Am. Med. Assoc., 1914, lxii, 1146. CrossrefGoogle Scholar3. MOONEDWARDS VHSR: Results of blood cultures in rheumatoid arthritis, Jr. Infect. Dis., 1917, xxi, 154-161. CrossrefGoogle Scholar4. BILLINGSCOLEMANHIBBS FGHWG: Chronic infectious arthritis: statistical report with end-results, Jr. Am. Med. Assoc., 1922, lxxviii, 1097-1105. Google Scholar5. BURBANKHADJOPOULOS RLG: Serologic significance of streptococci in arthritis and allied conditions, Jr. Am. Med. Assoc., 1925, lxxxiv, 637-641. CrossrefGoogle Scholar6. FORKNERSHANDSPOSTON CEARMA: Synovial fluid in chronic arthritis; bacteriology and cytology, Arch. Int. Med., 1928, xlii, 675-702. CrossrefGoogle Scholar7. CECILNICHOLLSSTAINSBY RLEEWJ: Bacteriology of blood and joints in chronic infectious arthritis, Arch. Int. Med., 1929, xliii, 571-605. CrossrefGoogle Scholar8. CECILNICHOLLSSTAINSBY RLEEWJ: Etiology of rheumatoid arthritis, Am. Jr. Med. Sci., 1931, clxxxi, 12-25. CrossrefGoogle Scholar9. SMALL JC: Rôle of streptococci in rheumatic diseases, Jr. Lab. and Clin. Med., 1929, xiv, 1144-1156. Google Scholar10. DAWSONOLMSTEADBOOTS MHMRH: Studies on etiology of rheumatoid arthritis; bacteriological investigations on blood, synovial fluid and subcutaneous nodules in rheumatoid arthritis, Proc Soc. Exper. Biol. and Med., 1931, xxviii, 419-420. CrossrefGoogle Scholar11. HADJOPOULOSBURBANK LGR: Correlation of experimental streptococcic arthritis in rabbits with chronic rheumatoid arthritis, Jr. Bone and Joint Surg., 1932, xiv, 471-500. Google Scholar12. COATESCOOMBS VCF: Observations on the rheumatic nodule, Arch. Dis. Childhood, 1926, i, 183-193. Google Scholar13. MENZER A: Serumbehandlung bei acutem und chronischem Gelenkrheumatismus, Ztschr. f. klin. Med., 1902, xlvii, 109-152. Google Scholar14. SWIFT HF: Rheumatic fever, Am. Jr. Med. Sci., 1925, clxx, 631-647. CrossrefGoogle Scholar15. SWIFTDERICKHITCHCOCK HFCLCH: Rheumatic fever as manifestation of hypersensitiveness (allergy or hyperergy) to streptococci, Trans. Assoc. Am. Phys., 1928, xliii, 192-202. Google Scholar16. SWIFTDERICKHITCHCOCK HFCLCH: Bacterial allergy (hyperergy) to nonhemolytic streptococci, Jr. Am. Med. Assoc., 1928, xc, 906-908. CrossrefGoogle Scholar17. SWIFT HF: Rheumatic fever; Hektoen lecture, Billings Foundation, Jr. Am. Med. Assoc., 1929, xcii, 2071-2083. (With full review of literature.) CrossrefGoogle Scholar18. ZINSSER H: Significance of bacterial allergy in infectious diseases, Bull. New York Acad. Med., 1928, iv, 351-383. Google Scholar19. ZINSSERYU HH: Bacteriology of rheumatic fever and allergic hypothesis, Arch. Int. Med., 1928, xlii, 301-309. CrossrefGoogle Scholar20. ANDREWSDERICKSWIFT CHCLHF: The skin response of rabbits to nonhemolytic streptococci. I. Description of a secondary reaction occurring locally after intradermal inoculation, Jr. Exper. Med., 1926, xliv, 35-53. Google Scholar21. DERICKSWIFT CLHF: Reactions of rabbits to nonhemolytic streptococci; general tuberculin-like hypersensitiveness, allergy or hyperergy following secondary reaction, Jr. Exper. Med., 1929, xlix, 615-636. CrossrefGoogle Scholar22. SWIFTDERICK HFCL: Reactions of rabbits to nonhemolytic streptococci; skin reactions in intravenously immunized animals, Jr. Exper. Med., 1929, xlix, 883-897. CrossrefGoogle Scholar23. DERICKHITCHCOCKSWIFT CLCHHF: Reactions of rabbits to nonhemolytic streptococci; study of modes of sensitization, Jr. Exper. Med., 1930, lii, 1-22. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Presented as a Clinic at the Montreal Meeting of the American College of Physicians, February 8, 1933.From the Arthritis Clinic of the New York Polyclinic Medical School and Hospital.†While this paper was in preparation the following articles appeared:1. CLAWSON, B. J., and FAHR, G. E.: Experiments leading to a possible basis for vaccine therapy in acute rheumatic fever, Proc. Soc. Exper. Biol. and Med., 1930, xxvii, 964-965.2. SWIFT, H. F., HITCHCOCK, C. H., DERICK, C. L., and MCEWEN, C.: Intravenous vaccination with streptococci in rheumatic fever, Am. Jr. Med. Sci., 1931, clxxxi, 1-11.3. WETHERBY, M., and CLAWSON, B. J.: Chronic arthritis, with special reference to intravenous vaccine therapy, Arch. Int. Med., 1932, xlix, 303-320.4. CLAWSON, B. J., and WETHERBY, M.: Experimental basis for intravenous vaccine therapy in chronic arthritis with summary of results obtained in patients, ANN. INT. MED., 1932, v, 1447-1461. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 November 1933Volume 7, Issue 5Page: 566-581KeywordsAllergy and immunologyArthritisClinical laboratoriesEtiologyHospitalsHyperthermiaResearch laboratoriesRheumatic feverVaccines ePublished: 1 December 2008 Issue Published: 1 November 1933 PDF downloadLoading ...