THE WALWORTH, WISCONSIN, EPIDEMIC OF HISTOPLASMOSIS
Authors: K R WILCOX, B A WAISBREN, J MARTIN
Journal: Annals of Internal Medicine (1958)

Article1 August 1958THE WALWORTH, WISCONSIN, EPIDEMIC OF HISTOPLASMOSISKENNETH R. WILCOX JR., M.D., BURTON A. WAISBREN, M.S., M.D., JOHN MARTIN, M.D.KENNETH R. WILCOX JR., M.D., BURTON A. WAISBREN, M.S., M.D., JOHN MARTIN, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-49-2-388 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptINTRODUCTIONOutbreaks of acute histoplasmosis are being recognized with increasing frequency. A recent article by Lehan and Furcolow1 summarizes reports of 38 epidemics in this country and three from foreign countries. Much useful information has been gained concerning the sources of and modes of infection with Histoplasma capsulatum from the study of these epidemics. The literature on histoplasmosis is adequately reviewed elsewhere 2-8 and will not be reviewed in detail in this presentation.This report is of an epidemic of acute histoplasmosis which has some unusual features. Exposure of various types to a single source of the organisms occurred over...Bibliography1. LehanFurcolow PHML: Epidemic histoplasmosis, J. Chron. Dis. 5: 489-503, 1957. CrossrefMedlineGoogle Scholar2. LehanFurcolow PHML: Proceedings of the Conference on Histoplasmosis, 1952, Public Health Monograph No. 39, U. S. Government Printing Office, Washington, D. C., 1956. Google Scholar3. SchwarzBaum JGL: The history of histoplasmosis, 1906 to 1956, New England J. Med. 256: 253-258, 1957. CrossrefMedlineGoogle Scholar4. SilvermanSchwarzLaheyCarson FNJMERP: Histoplasmosis, Am. J. Med. 19: 410-459, 1955. CrossrefMedlineGoogle Scholar5. Loosli CG: Histoplasmosis—some clinical, epidemiological and laboratory aspects, M. Clin. North America 39: 171-199, 1955. CrossrefGoogle Scholar6. Furcolow ML: The clinical diagnosis of histoplasmosis, Postgrad. Med. 20: 349-364, 1956. CrossrefMedlineGoogle Scholar7. ManosFerebeeKerschbaum NESHWF: Geographic variation in the prevalence of histoplasmin sensitivity, Dis. of Chest 29: 649-665, 1956. CrossrefMedlineGoogle Scholar8. EdwardsKlaer PQJH: World-wide geographic distribution of histoplasmosis and histoplasmin sensitivity, Am. J. Trop. Med. and Hyg. 5: 235-257, 1956. CrossrefMedlineGoogle Scholar9. Emmons CW: Isolation of Histoplasma capsulatum from soil, Pub. Health Rep. 64: 892-896, 1949. CrossrefMedlineGoogle Scholar10. LarshHintonFurcolow HWAML: Laboratory studies of Histoplasma capsulatum. III. Efficiency of the flotation method in isolation of Histoplasma capsulatum from soil, J. Lab. and Clin. Med. 41: 478-485, 1953. MedlineGoogle Scholar11. ZeidbergAjelloDillonRunyon LDLALC: Isolation of H. capsulatum from soil, Am. J. Pub. Health 42: 930-935, 1952. CrossrefGoogle Scholar12. ZeidbergAjello LDL: Environmental factors influencing the occurrence of Histoplasma capsulatum and M. gypseum in soil, J. Bact. 68: 156-159, 1954. CrossrefMedlineGoogle Scholar13. ZeidbergAjelloWebster LDLRH: Physical and chemical factors in relation to Histoplasma capsulatum in soil, Science 122: 33-34, 1955. CrossrefMedlineGoogle Scholar14. BabbittWaisbren DB: Roentgenographic picture of epidemic histoplasmosis. To be published. Google Scholar15. BronsonSchwarz SMJ: Roentgenographic patterns in histoplasmosis, Am. Rev. Tuberc. 76: 173-194, 1957. MedlineGoogle Scholar16. SalvinHottle SBGA: Factors influencing histoplasmin formation, J. Bact. 56: 541-546, 1948. CrossrefMedlineGoogle Scholar17. SchubertAjelloCooperRunyon JHLJSLC: Evaluation of histoplasmin and yeast phase antigens derived from a single strain of Histoplasma capsulatum in the complement fixation test, J. Bact. 69: 558-562, 1955. CrossrefMedlineGoogle Scholar18. HillCampbell GBCC: A further evaluation of histoplasmin and yeast phase antigens of Histoplasma capsulatum in the complement fixation test, J. Lab. and Clin. Med. 48: 255-263, 1956. MedlineGoogle Scholar19. SchubertAjelloStanfordGrant JHLSVO: Variations in complement fixation antigen production by different strains of Histoplasma capsulatum grown in two media, J. Lab. and Clin. Med. 41: 91-97, 1953. MedlineGoogle Scholar20. SchubertAjello JHL: Variation in complement fixation antigenicity of different yeast phase strains of Histoplasma capsulatum , J. Lab. and Clin. Med. 50: 304-307, 1957. MedlineGoogle Scholar21. AllanKoehlerStovall VJW: Yeast and mycelial phase titers of the complement fixation test for histoplasmosis. To be published. Google Scholar22. SteinbergJamborSuydam BAWPLO: Amphotericins A and B—two new antifungal antibiotics possessing high activity against deep-seated and superficial mycoses, Antibiotics Annual, 1955-56, pp. 574-578, Medical Encyclopedia, Inc., New York. Google Scholar23. LehanYatesBrasherLarshFurcolow PHJLCAHWML: Experiences with the therapy of sixty cases of deep mycotic infections, Dis. of Chest 32: 597-617, 1957. CrossrefMedlineGoogle Scholar24. WilcoxFeig.WaisbrenMartin KRMBAJ: Epidemiologic aspects of Walworth histoplasmosis outbreak. To be published. Google Scholar25. Edwards PQ: Personal communication. Google Scholar26. ZeidbergDillonGass LDARS: Some factors in the epidemiology of histoplasmin sensitivity in Williamson County, Tennessee, Am. J. Pub. Health 41: 80-88, 1951. CrossrefGoogle Scholar27. FurcolowSitterby MLJ: Further studies of the geography of histoplasmin sensitivity in Kansas and Missouri, J. Kansas M. Soc. 52: 584-588, 1951. MedlineGoogle Scholar28. SachsSmithFlemingFurcolow DRTDSML: The prevalence of positive reactions to tuberculin and histoplasmin in a rural Minnesota county, Am. J. Hyg. 62: 43-53, 1955. MedlineGoogle Scholar29. FellerFurcolowLarshLangmuirDingle AEMLHWADJH: Outbreak of unusual form of pneumonia at Camp Gruber, Oklahoma in 1944—follow-up studies implicating Histoplasma capsulatum as the etiologic agent, Am. J. Med. 21: 184-192, 1956. CrossrefMedlineGoogle Scholar30. LoosliProcknowTanziGraystonCombs CGJJFJTLW: Pulmonary histoplasmosis in a farm family—a three year follow-up, J. Lab. and Clin. Med. 43: 669-695, 1954. MedlineGoogle Scholar31. ChernissWaisbren EIBA: North American blastomycosis—a clinical study of 40 cases, Ann. Int. Med. 44: 105-123, 1956. LinkGoogle Scholar32. EdwardsPeeplesBerger LBWJAG: Prevalence of sensitivity to tuberculin and histoplasmin among high school students in Montgomery County, Maryland, Pediatrics 21: 389-396, 1958. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Presented in part at the Thirty-ninth Annual Session of The American College of Physicians, Atlantic City, New Jersey, April 28, 1958.From the Department of Medicine of Marquette University Medical School, St. Joseph's Hospital, the Wisconsin State Board of Health and the Communicable Disease Center, Public Health Service, USDHEW.Requests for reprints should be addressed to Burton A. Waisbren, M.D., Assistant Clinical Professor of Medicine, Marquette University School of Medicine, 208 E. Wisconsin Ave., Milwaukee, Wisconsin. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byOccupational Histoplasmosis: Epidemiology and Prevention MeasuresOcular HistoplasmosisApproach to the Diagnosis of the Endemic MycosesImprovements in diagnosis of histoplasmosisOcular HistoplasmosisDiagnosis and management of HistoplasmosisAn outbreak and review of cave-associated histoplasmosis capsulatiOutbreak of acute pulmonary histoplasmosis in members of a wagon trainHitchcock's Birds, or the Increased Rate of Exposure to Histoplasma from Blackbird Roost SitesA Large Urban Outbreak of Histoplasmosis: Clinical FeaturesLAWRENCE JOSEPH WHEAT, M.D., THOMAS G. SLAMA, M.D., HAROLD E. EITZEN, Ph.D., RICHARD B. KOHLER, M.D., MORRIS L. V. FRENCH, Ph.D., JAMES L. BIESECKER, M.D., Ph.D.Blackbird Roosts and Histoplasmosis An Increasing Medical Problem?Acute HistoplasmosisAcute histoplasmosis: Clinical, epidemiologic and serologic findings of an outbreak associated with exposure to a fallen treeThe Chanute Histoplasmosis EpidemicOutbreak of histoplasmosis associated with the 1970 earth day activitiesHistoplasmosisHistoplasmosisEcological and epidemiological studies of histoplasmosis in the United States of AmericaEnvironmental Aspects of HistoplasmosisAIRBORNE HISTOPLASMOSISThe Emerging Pattern of Urban HistoplasmosisNATURAL AND EXPERIMENTAL EPIDEMIOLOGY OF HISTOPLASMOSIS*Chronic active pulmonary histoplasmosis with cavitation 1 August 1958Volume 49, Issue 2Page: 388-418KeywordsConjunctivitisDyspneaEpidemiologyHistoplasma capsulatumHistoplasmosisHospital medicineHygieneMedical servicesMyalgiaResearch laboratories ePublished: 1 December 2008 Issue Published: 1 August 1958 PDF downloadLoading ...