THE TREATMENT OF SYSTEMIC BLASTOMYCOSIS WITH STILBAMIDINE
Authors: E B SCHOENBACH, J M MILLER, P H LONG
Journal: Annals of Internal Medicine (1952)

Article1 July 1952THE TREATMENT OF SYSTEMIC BLASTOMYCOSIS WITH STILBAMIDINEEMANUEL B. SCHOENBACH, M.D., F.A.C.P., JOSEPH M. MILLER, M.D., PERRIN H. LONG, M.D.EMANUEL B. SCHOENBACH, M.D., F.A.C.P.Search for more papers by this author, JOSEPH M. MILLER, M.D.Search for more papers by this author, PERRIN H. LONG, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-37-1-31 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlthough infrequent in occurrence, blastomycotic infections are important because of the morbidity and mortality associated with the systemic form of the disease. Treatment has been varied and generally ineffectual. The observation of Elson7 that certain of the diamidines exerted a fungistatic effect on Blastomyces dermatitidis led to the treatment of a patient suffering from systemic blastomycosis with two of the diamidines.Blastomycosis is seen in both the white and Negro races, usually in the third through the fifth decades of life and in the lower economic strata. The incidence is much higher in males. Farmers are more frequently affected than...Bibliography1. AraiSnapper HI: The influence of stilbamidine upon kidney function, liver and peripheral blood in multiple myeloma. Neurologic sequelae of stilbamidine therapy, New York State J. Med. 47: 1867-1874 (Sept.) 1947. MedlineGoogle Scholar2. BarberSlackWien HJRR: Increase in toxicity of stilbamidine solution on exposure to light, Nature, London 151: 107-108 (Jan. 23) 1943. CrossrefGoogle Scholar3. Bowesman C: A short report on the use of 4:4′ diamidino stilbene in the treatment of human sleeping sickness, Ann. Trop. 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WienFreemanScotcher RWNM: The metabolic effects produced by certain aromatic diamidines, Ann. Trop. Med. 37: 19-33 (April) 1943. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication March 19, 1952.Reviewed in the Veterans Administration and published with the approval of the Chief Medical Director. The statements and conclusions published by the authors are the result of their own study and do not necessarily reflect the opinion or policy of the Veterans Administration.From the Department of Medicine, State University of New York, College of Medicine at New York City, The Maimonides Hospital of Brooklyn, New York, and the Surgical Services, Veterans Administration, Fort Howard, Md. 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MILLER, M.D. 1 July 1952Volume 37, Issue 1Page: 31-47KeywordsArmed forcesBlastomycesBlastomycosisHospital medicineInfectious diseasesMorbidityMortalityPatientsRacial and ethnic issuesSystemic diseases ePublished: 1 December 2008 Issue Published: 1 July 1952 PDF downloadLoading ...