THE TREATMENT OF ACUTE CARBON TETRACHLORIDE POISONING WITH A REPORT OF TWO CASES
Authors: Benjamin R. Allison
Journal: Annals of Internal Medicine (1942)

Article1 January 1942THE TREATMENT OF ACUTE CARBON TETRACHLORIDE POISONING WITH A REPORT OF TWO CASESBENJAMIN R. ALLISON, M.D., F.A.C.P.BENJAMIN R. ALLISON, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-16-1-81 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe purpose of this paper is four-fold: (1) to present two cases of acute carbon tetrachloride poisoning (one fatal, with autopsy); (2) to discuss the treatment of this condition; (3) to call attention to the health hazard involved in its widespread use; and (4) to suggest that it be included in textbooks as a disease entity.CASE REPORTSCase 1. A nine-year-old boy, who had smeared red chalk on the covers of his bed, took a tin of cleaning fluid from the cupboard and in the process of cleaning found that he liked the odor of the fluid and the...Bibliography1. LAMSONMINOTROBBINS PDASBH: Prevention and treatment of carbon tetrachloride intoxication, Jr. Am. Med. Assoc., 1928, xc, 345-349. CrossrefGoogle Scholar2. WOKES F: Effect of calcium administration on carbon tetrachloride toxicity in mice, Quart. Jr. Pharm. and Pharmacol., 1933, vi, 413-417. Google Scholar3. CUTLER JT: The influence of diet on carbon tetrachloride poisoning in dogs, Jr. Pharmacol. and Exper. Therap., 1932, xlv, 209-226. Google Scholar4. MINOT AS: Mechanism of hypoglycemia produced by guanidine and carbon tetrachloride poisoning, Jr. Pharmacol. and Exper. Therap., 1931, xliii, 295-313. Google Scholar5. BOLLMANMANN JLFC: Experimentally produced lesions of the liver, ANN. INT. MED., 1931, v, 699-712. Google Scholar6. LACQUET AM: Experimental pathology of the liver: effects of carbon tetrachloride on normal and on restored liver after hepatectomy, Arch. Path., 1932, xiv, 164-176. Google Scholar7. CAMERONKARUNARATNE RWA: Carbon tetrachloride cirrhosis in relation to liver regeneration, Jr. Path. and Bact., 1936, xlii, 1-21. CrossrefGoogle Scholar8. PEERY TM: A study of carbon tetrachloride poisoning: stages of hepatic damage and repair in man, Arch. Path., 1938, xxvi, 923-941. Google Scholar9. FRANCO S: Nephritic syndromes caused by industrial poisoning with carbon tetrachloride, New York State Jr. Med., 1936, xxxvi, 1847-1853. Google Scholar10. SEMETRA H: Nephrosis due to carbon tetrachloride, Arch. Int. Med., 1939, lxiii, 760-777. Google Scholar11. FORBESNEALE JCRC: A new preparation protecting against rat liver necrosis, Proc. Soc. Exper. Biol. and Med., 1936, xxxiv, 319-320. CrossrefGoogle Scholar12. FORBES JC: Studies on the prevention of liver cirrhosis by the sub-cutaneous injections of xanthine containing preparations, Jr. Pharmacol. and Exper. Therap., 1939, lxv, 287-293. Google Scholar13. NEALEWINTER RCHC: Identification of active crystalline substance from liver which protects against liver damage due to chloroform or carbon tetrachloride: Study of related compounds, Jr. Pharmacol. and Exper. Therap., 1938, lxii, 127-148. Google Scholar14. FORBESOUTHOUSE JCEL: Studies on the mechanism of the protective action of xanthine against carbon tetrachloride poisoning, Jr. Pharmacol. and Exper. Therap., 1940, lxviii, 185-193. Google Scholar15. BARRETTMACLEANMCHENRY HMDLEW: Experiments with an "antinarcotic" material prepared from liver, Jr. Pharmacol. and Exper. Therap., 1938, lxiv, 131-137. Google Scholar16. FITZHUGH OG: Liver regeneration in rats protected with xanthine against carbon tetrachloride poisoning, Proc. Soc. Exper. Biol. and Med., 1939, xl, 11-15. CrossrefGoogle Scholar17. SMYTHSMYTH HFHF: Safe practices in the industrial use of carbon tetrachloride, Jr. Am. Med. Assoc., 1936, cvii, 1683-1687. CrossrefGoogle Scholar18. DAVIS PA: Carbon tetrachloride as an industrial hazard, Jr. Am. Med. Assoc., 1934, ciii, 962-966. CrossrefGoogle Scholar19. SMYTH HF: Carbon tetrachloride in industry, Indust. Med., 1935, iv, 12-15. Google Scholar20. Volatile poisons in the American home: Editorial, Jr. Am. Med. Assoc., 1933, ci, 1238-1239. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Hewlett, Long Island*Received for publication February 6, 1941.From the medical service of the Nassau Hospital, Mineola, Long Island. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byMechanism of ethanol induced hepatic injuryEffects of Alcohol on Other Hepatotoxins 1 January 1942Volume 16, Issue 1Page: 81-93KeywordsAutopsyMedical servicesTetrachloride ePublished: 1 December 2008 Issue Published: 1 January 1942 PDF downloadLoading ...