SPONTANEOUS RUPTURE OF THE SPLEEN DURING MALARIA THERAPY; REPORT OF A CASE
Authors: Lawrence I. Kaplan, Hilton S. Read, Dewitt F. Mullins
Journal: Annals of Internal Medicine (1946)

Case Reports1 April 1946SPONTANEOUS RUPTURE OF THE SPLEEN DURING MALARIA THERAPY; REPORT OF A CASELAWRENCE I. KAPLAN, HILTON S. READ, DEWITT F. MULLINSLAWRENCE I. KAPLANSearch for more papers by this author, HILTON S. READSearch for more papers by this author, DEWITT F. MULLINSSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-24-4-707 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe rarity of spontaneous rupture of the spleen in naturally acquired malarial infections has been expressed by Manson-Bahr,1Stitt,2and Osler.3Since the introduction of malaria as a therapeutic agent in the management of neurosyphilis, 31 cases of splenic rupture during treatment have been reported in the literature, either in detail or as personal references. Since this total cannot include unreported cases and cases that have not been recognized, the incidence of the complication probably approaches at least twice that number. Only one known case of recovery has followed splenectomy.4In view of the gravity and unpredictability of this almost...Bibliography1. MANSON-BAHR PH: Manson's tropical diseases, 8th Edition, Revised, 1926, William Wood and Company, Division of Williams and Wilkins Co., Baltimore. Google Scholar2. STRONG RP: Stitt's diagnosis, prevention and treatment of tropical diseases, 6th Edition in 2 vols., 1943, The Blakiston Co., Philadelphia. Google Scholar3. OSLERMCCRAE WT: The principles and practice of medicine, 1922, D. Appleton-Century Co., New York. Google Scholar4. VERMEYLENVERVAECK GP: Les formes psychosiquez chez les paralytiques généraux malarises et la notion de démence paralytique, Encephale, 1930, xxv, 563 and 643. Google Scholar5. 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CrossrefGoogle Scholar33. BIGLANDWATSONBIGLAND PMGAAD: Relation between general paralysis and somatic syphilis, Lancet, 1924, ii, 588-593. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Thomasville, Georgia*Received for publication July 16, 1945.From Finney General Hospital. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySevere MalariaPlasmodium vivax 1 April 1946Volume 24, Issue 4Page: 707-714KeywordsMalariaSpleen ePublished: 1 December 2008 Issue Published: 1 April 1946 PDF downloadLoading ...