tbuckley/cabot-search huggingface dataset:
Elder Abuse as a Risk Factor for Hospitalization in Older Persons
Authors: XinQi Dong, Melissa A. Simon
Journal: JAMA Internal Medicine (2013)

<h3>Importance</h3>Elder abuse is associated with increased mortality risk. However, the relationship between elder abuse and health care services utilization remains unclear.<h3>Objective</h3>To examine the relationship between overall elder abuse and specific subtypes of elder abuse and rate of hospitalization in a community-dwelling population of older adults.<h3>Design</h3>Prospective population-based study.<h3>Setting</h3>Chicago Health and Aging Project.<h3>Participants</h3>Of the 6674 community-dwelling older adults who participated in the Chicago Health and Aging Project, 106 were identified by social services agencies for elder abuse.<h3>Main Outcomes and Measures</h3>The primary predictor was elder abuse (reported and confirmed) reported to social services agency. The outcome of interest was the annual rate of hospitalization obtained from the Centers for Medicare and Medicaid Services. Poisson regression models were used to assess these longitudinal relationships.<h3>Results</h3>The unadjusted mean annual rate of hospitalization was 0.62 (95% CI, 0.59-0.66) for those without elder abuse and 1.97 (95% CI, 1.33-2.61) for those with reported elder abuse. After adjusting for sociodemographic and socioeconomic variables, medical comorbidities, cognitive and physical function, and psychosocial well-being, reported elder abuse had higher rates of hospitalization (rate ratio [RR], 2.00 [95% CI, 1.45-2.75]). Psychological abuse (RR, 2.22 [95% CI, 1.44-3.43]), financial exploitation (RR, 1.75 [95% CI, 1.06-2.90]), caregiver neglect (RR, 2.43 [95% CI, 1.60-3.69]), and 2 or more types of elder abuse (RR, 2.59 [95% CI, 1.82-3.66]) were associated with increased rates of hospitalization, after considering the same potential confounders. Results from interaction term analyses suggested that the association between elder abuse and hospitalization did not differ across the levels of medical comorbidities, cognitive and functional impairment, or psychosocial distress.<h3>Conclusions and Relevance</h3>Elder abuse was associated with increased rates of hospitalization in this community population. Future research is needed to explore the causal mechanisms between elder abuse and hospitalization. As we enter the era of health care reform, an improved understanding of factors that increase rates of hospitalization could also have significant implications for social and health policy as well as clinical care of the vulnerable patients.
Use of Insulin Glargine During the First Weeks of Pregnancy in Five Type 1 Diabetic Women
Authors: Graziano Di Cianni, Laura Volpe, Cristina Lencioni, Kyriazoula Chatzianagnostou, Ilaria Cuccuru, Alessandra Ghio, Luca Benzi, Stefano Del Prato
Journal: Diabetes Care (2005)

The long-acting analog glargine is a new insulin with 24-h persistence. This peculiar peakless action profile accounts for significant risk reduction for nocturnal hypoglycemia and a more stable daily plasma glucose profile (1,2). Only a few reports have described the use of insulin glargine during human pregnancy, so its use is not recommended at present. Animal studies have addressed the safety and efficacy of glargine during pregnancy, showing no direct effect on reproduction and embryo-fetal development (3 ) . Recently, Devlin et al. (4) and Holstein et al. (5) reported the use of insulin glargine in two type 1 diabetic women; both cases were free of any pregnancy complications and …
Cirrhosis, hepatic encephalopathy, and propranolol.
Authors: P Watson, J R Hayes
Journal: BMJ (1983)

between concentrations of serum folate and those of anticonvulsant, impairment of folate absorption by anticonvulsant is usually presumned to be the cause.The possibility that folate supplements might act to reduce plasma anticonvulsant levels by affecting their metabolism does not seem to have been considered.In Reynolds's study3 folate seemed to render the anticonvulsants less effective, though frequency of fits was not affected by folate supplements in the present work.Perhaps the problem might be clarified if free anticonvulsant levels were measured, as only these are relevant to anticonvulsant efficacy.Using ultrafiltration, we have found free levels to vary from 14% to 17% of the total during pregnancy for phenytoin and from 52% to 78% for phenobarbitone, in serial estimations on a single pregnant patient.Variation between patients in degree of binding, and consequently in free anticonvulsant levels, is wider.
Lippincott Williams &amp;amp; Wilkins Atlas of Anatomy
Authors: Jason M. Organ
Journal: JAMA (2009)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Benign Epithelial Hyperplasia of the Esophagus: Glycogenic Acanthosis
Authors: G. Clémençon, F. Gloor
Journal: Endoscopy (1974)

Among 364 esophagogastroscopies performed within 9 months glycogenic acanthosis of the esophagus was diagnosed in 24 cases. These fine whitish plaques of epithelial hyperplasia of the mucosa, which can be mistaken for leukoplacia when reaching a larger size, stain dark-blue with Lugol's solution. The squamous rounded epithelial cells are extremely rich in glycogen. The incidence in our material is 6.6%. In 62.5% of these cases endoscopic signs of cardiac incompetence were found and in 45.8% of refluxesophagitis, whereas the incidence of the latter was but 12.9% in the whole material. It seems amazing that this frequent but harmless lesion has not yet been given more attention. Considering the necessity to recognize early cancer, such small lesions should, as a matter of fact, not be overlooked. Biopsy material should be fixed in alcohol for histology.
AIDS and the condom.
Authors: K Wellings
Journal: BMJ (1986)

Distribution and use of the condom in the context of AIDS (acquired immunodeficiency syndrome) prevention in Britain is under consideration.  There are a few small studies that suggest that the AIDS virus HIV as well as other retroviruses do not penetrate condoms.  Furthermore nonoxynol-9 the common spermicide seems to inactivate HIV in vitro.  Although larger studies using specific brands in real situations need to be done it is time to mount a major public information campaign on evidence for the protective effects of condoms and spermicides.  Even though 26% of the public say such advertising on television would discomfit them the sensitivities of a minority should be set aside when lives are at risk.  The National Health Service provides condoms free of charge for family planning but does not as yet do so for prophylaxis.  Efforts to block the spread of AIDS should be centrally coordinated.
TRIPLE REGIMEN OF SELECTIVE DECONTAMINATION OF THE DIGESTIVE TRACT, SYSTEMIC CEFOTAXIME, AND MICROBIOLOGICAL SURVEILLANCE FOR PREVENTION OF ACQUIRED INFECTION IN INTENSIVE CARE
Authors: IainMca. Ledingham, AnneT. Eastaway, IanC. Mckay, StephenR. Alcock, JohnC. Mcdonald, Graham Ramsay
Journal: The Lancet (1988)
Postinfluenzal Vomiting With Symptoms Of Lethargic Encephalitis
Authors: ALBERT S. WELCH
Journal: Annals of Internal Medicine (1929)

Article1 May 1929Postinfluenzal Vomiting With Symptoms Of Lethargic EncephalitisALBERT S. WELCH, A.B., M.D.ALBERT S. WELCH, A.B., M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-2-11-1194 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptDuring the past few months, in a practice consisting chiefly of diseases with prominent symptoms referable to the alimentary tract, there have come to attention several unusual cases in which the chief complaint was vomiting; and examinations failed to yield data upon which they could be classified in any of the well-known groups of conditions in which vomiting is an outstanding symptom. A cursory investigation among other members of the medical profession of this city brought to light a few similar cases, diagnosed doubtfully as "neurotic vomiting" "nervous indigestion" or "food poisoning." In each instance, the physician could not recollect...(1) Economo Cv: Encerhalitis lethargica, Wien Klin. Wochschr. 30, No. 19: 581, May 10, 1917. Google Scholar(2) Hall AJ: Epidemic Encephalitis, Wm. Wood and Co., 1924, P. 5. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: University of Kansas School of Medicine Kansas City, Missouri PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 May 1929Volume 2, Issue 11Page: 1194-1197KeywordsEncephalitisFood poisoningVomiting Issue Published: 1 May 1929 PDF downloadLoading ...
96. Ocular Gene Transfer Using EIAV Vectors and an RPE-Specific Promoter
Authors: Shu Kachi, Katie Binley, Naoyasu Umeda, Hideo Akiyama, Raquel Lima e Silva, Wei-Hong Xiao, Michiko Kachi, Margaret Esapa, Sharifah Iqball, Stuart Naylor, Peter A. Campochiaro
Journal: Molecular Therapy (2005)

EIAV vectors have been shown to have substantial potential for long-term expression of transgenes, but the optimal promoter for various applications has not been worked out. In this study, we compared EIAV-mediated ocular gene transfer using a CMV promoter with that using the vitelliform macular dystrophy 2 (VMD2) promoter which is retinal pigmented epithelium (RPE)-specific. Seven days after subretinal injection of 2.0x105 TU of EIAV.CMV/LacZ in Balb/C mice, there was strong X-gal staining in the RPE throughout the region where the retina had been detached by the injection. The staining was stronger 28 days after injection and was still prominent 56 days post-injection, the longest time point examined. Staining was also seen in corneal endothelial cells, iris, ciliary body, a few ganglion cells, and the optic nerve. The staining in optic nerve suggests that after subretinal injection of vector, protein derived from the transgene may gain access to the brain via anterograde transport from transduced ganglion cells. Seven days after subretinal injection of 2.0x105 TU of EIAV.VMD2/LacZ, there was strong X-gal staining in the RPE, which became stronger on day 28, and was still strong on day 56, the last time point examined. Unlike the results with EIAV.CMV/LacZ, there was no staining in the optic nerve indicating that the VMD2 promoter prevented gene expression in the ganglion cells. These data indicate that long term expression of transgenes can be achieved in RPE cells using a combination of EIAV vectors and the VMD2 promoter.
Form and Function in the Federal Health Effort
Authors: Charles C. Edwards
Journal: New England Journal of Medicine (1976)

In March, 1975, shortly after leaving the post of Assistant Secretary for Health, I offered some observations on the federal health effort in an article appearing in the Journal (N Engl J Med 292:559–562, 1975). At that time, I raised the question whether the leadership in either the public or the private health sector was in a position to influence the making of national health policy in the face of political pressures being exerted by the Congress and the White House, neither of which, in my view, is equipped to make sound judgments without expert guidance from the health enterprise. . . .
Reflux Into Redundant Duodenal Stump of Pancreatic Allograft Imitates Duodenal Stump Leak on Tc-99m MAG3 Imaging
Authors: STEPHEN FREYALDENHOVEN, GLENN A. HALFF, ROBERT M. ESTERL
Journal: Clinical Nuclear Medicine (1997)

Tc-99m MAG3 scintigraphy is useful in the diagnosis of renal-pancreatic allograft dysfunction. A 35-year-old man who had a cadaveric kidney-pancreas transplant 6 weeks earlier was admitted for acute allograft rejection. A pelvic sonogram showed a large peripancreatic fluid collection. A Tc-99m MAG3 scan showed reflux in to the large, redundant duodenal stump of pancreatic allograft, which was initially mistaken to be a leak from the duodenal stump. The peripancreatic fluid collection was later identified to be a lymphocele (not a urinoma or duodenal stump leak). The authors present this case to emphasize that knowledge of the transplant anatomy, as well as clinical symptomatology, is essential before the diagnosis of a duodenal stump leak can be made.
CALCINEURIN INHIBITOR-FREE IMMUNOSUPPRESSION AFTER HEART TRANSPLANTATION: TRADING IMPROVING RENAL FUNCTION FOR RISK OF ACUTE AND CHRONIC REJECTION IN FOLLOW-UP?
Authors: Miriam Freundt, Philipp Kolat, ssad Haneya, Leopold Rupprecht, Esther Kellner, Stephan Hirt, Christof Schmid
Journal: Journal of the American College of Cardiology (2014)
Traditional Chinese Medicine in The United States
Authors: Frederick P. Li
Journal: JAMA (1972)

<h3>To the Editor.—</h3> The practice in the People's Republic of China of both traditional Chinese medicine and modern Western medicine may be enigmatic to American physicians.<sup>1</sup>However, dual systems of medicine exist in the United States within certain ethnic subcultures,<sup>2</sup>such as Chinese-American communities. Most Chinese-Americans receive their health care from a physician. Some also take traditional Chinese medicines, according to a recent health survey in one US chinatown.<sup>3</sup>The chief forms of therapy in the traditional Chinese system are herb medicines, acupuncture, and moxibustion.<sup>4</sup>Herbal teas and salves are sometimes used concurrently with medications prescribed by a physician. Acupuncture, the insertion of needles into points in the body specified by the type of illness, is available in some large US chinatowns for the treatment of a variety of disorders. It has not been administered as anesthesia for major surgery, as practiced in the People's Republic
Evidence for a disease-promoting effect of Staphylococcus aureus–derived exotoxins in atopic dermatitis
Authors: Rita Bunikowski, Martin E.A. Mielke, Horst Skarabis, Magitta Worm, Ioannis Anagnostopoulos, Gerhard Kolde, Ulrich Wahn, Harald Renz
Journal: Journal of Allergy and Clinical Immunology (2000)
In treatment-resistant depression, adding cognitive–behavioral therapy to usual care was cost-effective at 1 y
Authors: Gregory Simon
Journal: Annals of Internal Medicine (2014)

Source Citation Hollinghurst S, Carroll FE, Abel A, et al. Cost-effectiveness of cognitive-behavioural therapy as an adjunct to pharmacotherapy for treatment-resistant depression in primary care: economic evaluation of the CoBalT Trial. Br J Psychiatry. 2014;204:69-76. 24262818
Activation of complement-a mechanism for the inflammation in acne
Authors: D.G. SCOTT, W.J. CUNLIFFE, G. GOWLAND
Journal: British Journal of Dermatology (2006)

Journal Article Activation of complement—a mechanism for the inflammation in acne Get access D.G. SCOTT, D.G. SCOTT University Departments of Immunology, The General Infirmary, Leeds LS1 3EX Search for other works by this author on: Oxford Academic Google Scholar W.J. CUNLIFFE, W.J. CUNLIFFE University Departments of Dermatology, The General Infirmary, Leeds LS1 3EX Search for other works by this author on: Oxford Academic Google Scholar G. GOWLAND G. GOWLAND University Departments of Immunology, The General Infirmary, Leeds LS1 3EX Professor G. Gowland, Department of Immunology, The General Infirmary, Leeds LS1 3EX. Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 101, Issue 3, 1 September 1979, Pages 315–320, https://doi.org/10.1111/j.1365-2133.1979.tb05625.x Published: 01 September 1979
Outcome of Endoscopic Sphincterotomy in Patients with Pain of Suspected Biliary Or Papillary Origin and Inconclusive Cholangiography Findings
Authors: B. Brand, L. Wiese, F. Thonke, P. V. Sriram, S. Jaeckle, U. Seitz, S. Bohnacker, N. Soehendra
Journal: Endoscopy (2001)

Background and Study Aims: We prospectively studied the outcome of endoscopic sphincterotomy in symptomatic patients with elevated liver enzyme levels but no clear evidence of biliary pathology on transabdominal ultrasound and diagnostic endoscopic retrograde cholangiography (ERC).
PSYCHIATRIC SYMPTOMS AND SYNDROMES IN PARKINSON'S DISEASE
Authors: ROBERT S. SCHWAB, HOWARD D. FABING, JOHN S. PRICHARD
Journal: American Journal of Psychiatry (1951)

1. The psychiatric symptoms and syndromes associated with Parkinson's disease are of 4 general types: (1) psychiatric diseases unrelated to Parkinsonism, (2) reactive mental disturbances, (3) psychiatric symptoms caused by medication, and (4) paroxysmal psychiatric disorders probably related to Parkinson's disease. 2. Examples of the 4 types are described in a series of more than 200 patients with the disease. 3. The paroxysmal psychiatric disorders usually associated with oculogyric crises (Type 4) are of special interest in that they often comprise formes frustres of psychoses and neuroses, and afford an opportunity for study of the neural correlates of many types of mental disorders.
Antibiotic Drugs in Cholera
Authors: CRAIG K. WALLACE
Journal: Annals of Internal Medicine (1968)

Editorial Notes1 July 1968Antibiotic Drugs in CholeraCRAIG K. WALLACE, M.D., EUGENE J. GANGAROSA, M.D.CRAIG K. WALLACE, M.D.Search for more papers by this author, EUGENE J. GANGAROSA, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-69-1-166 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptA cholera pandemic, caused by Vibrio cholerae biotype El Tor, has spread from its endemic focus in Indonesia since 1960. Southeast and South Asia have been affected, and even now the Middle East is threatened. There is great concern about further extension by means of rapid ground and air travel from multiple-infected foci and a totally unpredictable pattern of geographic spread. Cholera terrorizes a population. It strikes swiftly. Mortality may exceed 60%, especially where medical facilities are inundated and practitioners are unfamiliar with treatment.Therapy has been simple and dramatically successful since Watten and coworkers (1) introduced the concept that...References1. WATTENMORGANSONGKHLAVANIKIATIPHILLIPS RHFMYBRA: Water and electrolyte studies in cholera. J. Clin. Invest. 38: 1879, 1959. CrossrefMedlineGoogle Scholar2. WALLACEFABIEMANGUBATVELASCOJUINIOPHILLIPS CKAEOECRA: The 1961 cholera epidemic in Manila, Republic of the Philippines. Bull. WHO 30: 795, 1964. MedlineGoogle Scholar3. CARPENTERSACKMONDALMITRA CCRBAPP: Tetracycline therapy in cholera. J. Indian Med. Ass. 43: 309, 1964. MedlineGoogle Scholar4. GREENOUGHGORDONROSENBERGBENENSONDAVIES WBRSISASBJ: Tetracycline in the treatment of cholera. Lancet 1: 355, 1964. CrossrefMedlineGoogle Scholar5. LINDENBAUMGREENOUGHISLAM JWBMR: Antibiotic therapy of cholera. Bull. WHO 36: 871, 1967. MedlineGoogle Scholar6. LINDENBAUMGREENOUGHISLAM JWBMR: Antibiotic therapy of cholera in children. Bull. WHO 37: 529, 1967. MedlineGoogle Scholar7. WALLACECARPENTERMITRASACKKHANRAWERNERDUFFYOLEINICKLEWIS CKCCPPRBSRASTPAGW: Oral tetracycline therapy in cholera. Trans. Roy. Soc. Trop. Med. Hyg. 59: 621, 1965. CrossrefGoogle Scholar8. GANGAROSASAGHARIEMILESIADAT EJHJH: Detection of Vibrio cholerae biotype El Tor by purging. Bull. WHO 34: 363, 1966. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAntimicrobial drugs for treating cholera 1 July 1968Volume 69, Issue 1Page: 166-167KeywordsAntibioticsCholeraDrugsMortalityVibrio cholerae ePublished: 1 December 2008 Issue Published: 1 July 1968 PDF downloadLoading ...
Acute Fulminant Aortic and Mitral Insufficiency in Ankylosing Spondylitis
Authors: Stephen R. Stewart, Dick L. Robbins, James J. Castles
Journal: New England Journal of Medicine (1978)

EXTRASKELETAL manifestations of ankylosing spondylitis include aortitis with aortic1 , 2 and rarely mitral3 , 4 valvular insufficiency. Cardiac dysfunction usually develops late and progresses slowly.1 The acute case of aortitis presented below required emergency bivalvular replacement antedating spondylitis.Case ReportA 16-year-old boy was admitted to Sacramento Medical Center, on August 10, 1971, with a three-week history of exertional dyspnea, constitutional symptoms and a 4-kg weight loss. The history was negative for previous murmurs.The blood pressure was 120/50 mm Hg, the pulse 90, and the temperature 37.0°C. The precordium was hyperactive, with a Grade IV of VI harsh systolic murmur at the . . .
Effect of Helicobacter pylori eradication on the treatment of gastro-oesophageal reflux disease
Authors: J E Richter
Journal: Gut (2004)

The important issue of whether Heliobacter pylori eradication leads to increased reflux has been the subject of many apparently contradictory publications, but when we asked two leading authorities to give us their views, there turned out to be considerable consensus, as you can read below.