SOME UNUSUAL OBSERVATIONS IN POST TRANSFUSION REACTIONS: TWO CASES WITH AUTOPSY FINDINGS
Authors: V A DIGILIO, A HOCHWALD
Journal: Annals of Internal Medicine (1949)

Article1 April 1949SOME UNUSUAL OBSERVATIONS IN POST TRANSFUSION REACTIONS: TWO CASES WITH AUTOPSY FINDINGSVICTOR A. DIGILIO, M.D., ADOLF HOCHWALD, M.D.VICTOR A. DIGILIO, M.D.Search for more papers by this author, ADOLF HOCHWALD, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-30-4-745 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe renal pathologic lesion following hemolysis of transfused blood has been described many times (Bordley,1 Goldring and Graef2; DeGowin, Warner and Randall3; Dardinski4; Payne5; Witts,6 among others). Lesions of other viscera have also been observed, but reported less frequently (Bordley, Goldring and Graef; Dardinski).The relationship of intravascular hemolysis to the resulting renal disease and lesions of other viscera does not appear to be clear. Indeed, some difference of opinion still exists relative to the pathogenesis of the so-called transfusion kidney.3The two cases to be reported herein because of marked differences in the duration of life after the transfusion...Bibliography1. BORDLEY J: Reactions following transfusion of blood, with urinary suppression and uremia, Arch. Int. Med., 1931, xlvii, 288-315. CrossrefGoogle Scholar2. GOLDRINGGRAEF WI: Nephrosis with uremia following transfusion with incompatible blood—Report of seven cases with three deaths, Arch. Int. Med., 1936, lviii, 825-845. CrossrefGoogle Scholar3. DEGOWINWARNERRANDALL ELEDWL: Renal insufficiency from blood transfusions. II. Anatomic changes in man compared with those in dogs with experimental hemoglobinuria, Arch. Int. Med., 1938, lxi, 609-630. CrossrefGoogle Scholar4. DARDINSKI VJ: The pathology of anuria in an Rh-negative patient, Am. Jr. Clin. Path., 1945, xv, 286-288. CrossrefGoogle Scholar5. PAYNE RV: Acute hemolytic anemia—Death after transfusion, Guy's Hosp. Rep., 1934, lxxxiv, 65. Google Scholar6. WITTS LJ: A note on blood transfusion with an account of a fatal reaction, Lancet, 1929, i, 1297. CrossrefGoogle Scholar7. LEHANE D: Transient blindness following blood transfusion, Brit. Med. Jr., 1941, ii, 694. CrossrefGoogle Scholar8. ROBINSON G: An unusual sequel to blood transfusion, Brit. Med. Jr., 1941, ii, 728. CrossrefGoogle Scholar9. BAKERDODDS SLEC: Obstruction of the renal tubules during the excretion of hemoglobin, Brit. Jr. Exper. Path., 1945, vi, 247. Google Scholar10. AYERGAULD GDAG: Uremia following blood transfusion, Arch. Path., 1942, xxxiii, 513. Google Scholar11. KIMMELSTIEL P: Acute hematogenous interstitial nephritis, Am. Jr. Path., 1938, xiv, 737. Google Scholar12. EPPINGERKANNITZPOPPER : Die seroese Entzuendung; eine Permeabilitaets—Pathologie, 1935, Springer, Wien. Google Scholar13. NONNENBRUCH W: Ueber das entzuendliche Oedem der Niere und das hepatorenale Syndrom, Deutsch. med. Wchnschr., 1937, lxiii, 7. CrossrefGoogle Scholar14. MARIOTTKETTURICK HLA: Volume and rate in blood transfusion for the relief of anemia, Brit. Med. Jr., 1940, i, 1043. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication January 15, 1948.From the Departments of Medicine and Pathology of the Woman's Medical College, Philadelphia, Pa. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byExperimentelle NierenkrankheitenExperimentelle NierenkrankheitenBlut und BlutersatzpräparateBlut und BlutersatzpräparateTHE NATURAL HISTORY AND MANAGEMENT OF HÆMOLYTIC TRANSFUSION REACTIONS 1 April 1949Volume 30, Issue 4Page: 745-756KeywordsAutopsyBloodGratitudeLesionsPathogenesisRenal diseases ePublished: 1 December 2008 Issue Published: 1 April 1949 PDF downloadLoading ...