HYPERVITAMINOSIS A: REPORT OF A CASE IN AN ADULT MALE
Authors: Ernest W. Shaw, Juan Z. Niccoli
Journal: Annals of Internal Medicine (1953)

Case Reports1 July 1953HYPERVITAMINOSIS A: REPORT OF A CASE IN AN ADULT MALEERNEST W. SHAW, JUAN Z. NICCOLI, M.D.ERNEST W. SHAWSearch for more papers by this author, JUAN Z. NICCOLI, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-39-1-131 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe syndrome of hypervitaminosis A has been described in at least 17 infants and young children since Josephs' original article in 1944.1, 2 Sulzberger and Lazar3 described similar toxic symptoms which occurred in an adult female who took large amounts of vitamin A in an attempt to prevent colds. Rodahl4 has described the toxic symptoms of hypervitaminosis A resulting from polar bear liver ingestion.The present report is of an adult male with this syndrome and demonstrates several interesting features.CASE REPORTPresent Illness:A 25 year old Mexican drug store clerk was first seen by us on March 3,...Bibliography1. Josephs HW: Hypervitaminosis A and carotinemia, Am. J. Dis. Child. 67: 33 (Jan.) 1944. Google Scholar2. ToomeyMorissette JARA(a) : Hypervitaminosis A, Am. J. Dis. Child. 73: 473 (April) 1947. (b) Rothman, P. E., and Leon, E. E.: Hypervitaminosis A, Radiology 51: 368, 1948. (c) Dickey, L. B., and Bradley, E. J.: Hypervitaminosis A: case report, Stanford M. Bull. 6: 345, 1948. (d) Fried, C. T., and Grand, M. J. H.: Hypervitaminosis A, Am. J. Dis. Child. 79: 475 (March) 1950. (e) Caffey, J.: Chronic poisoning due to excess of vitamin A, Pediatrics 5: 672, 1950. (f) Bair, G.: Chronic vitamin A poisoning: report of a case, J. A. M. A. 146: 1573 (Aug. 25) 1951. (g) Gribetz, D., Silverman, S. H., and Sobel, A. E.: Vitamin A poisoning, Pediatrics 7: 305 (March) 1951. (h) Rineberg, I. E., and Gross, R. J.: Hypervitaminosis A with infantile cortical hyperostosis, J. A. M. A. 146: 1222 (July 28) 1951. (i) Wyatt, T. C., Carabello, C. A., and Fletcher, M. E.: Hypervitaminosis A, report of a case, J. A. M. A. 144: 304 (Sept. 23) 1950. (j) Mouriguard, A. G.: Overdosage with vitamin A, Presse méd. 56: 737 (Oct. 24) 1948. (k) Caffey, J.: Chronic poisoning due to excess of vitamin A, Am. J. Roentgenol. 65: 12 (Feb.) 1951. (l) Naz, J. F., and Edwards, W. M.: Hypervitaminosis A, New England J. Med. 246: 87 (Jan. 17) 1952. MedlineGoogle Scholar3. SulzbergerLazar MBMP: Hypervitaminosis A. Report of a case in an adult, J. A. M. A. 146: 788 (June 30) 1951. CrossrefMedlineGoogle Scholar4. Rodahl K: The toxic effect of polar bear liver, Skrifter Nr. 92, Norsk Polarinstitutt and Ibid., Hypervitaminosis A, a study of the effect of excess of vitamin A in experimental animals, Skrifter Nr. 95, Norsk Polarinstitutt. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication January 30, 1953.Permanent address of senior author: 1870 4th Ave., San Diego, Calif. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byIsotretinoin and neuropsychiatric side effects: Continued vigilance is neededAn infant with hypercalcemia and rachitic changesCase of Hypercalcemia Secondary to Hypervitaminosis A in a 6-Year-Old Boy with AutismThe neurobiology of retinoic acid in affective disordersHypercalcemia caused by iatrogenic hypervitaminosis AOverview of Existing Research and Information Linking Isotretinoin (Accutane), Depression, Psychosis, and SuicideHigh Serum Retinyl Esters Are Not Associated with Reduced Bone Mineral Density in the Third National Health and Nutrition Examination Survey, 1988-1994Vitamin A in acne vulgarisHypervitaminosis A syndrome: A paradigm of retinoid side effectsPibloktoq (hysteria) and inuit nutrition: Possible implication of hypervitaminosis ALiver damage with reversible portal hypertension from vitamin A intoxication: demonstration of Ito cells.Case Report Vitamin A Toxicity and HypercalcemiaVitamin Excess and ToxicityOral Vitamin A in Acne Vulgaris Preliminary ReportOral Vitamin A (Retinol) in Acne VulgarisCHRONIC VITAMIN A INTOXICATIONChronic adult hypervitaminosis A with hypercalcemiaA Conspectus of Research on Vitamin A Requirements of ManHYPERVITAMINOSIS A WITH HYPERCALCÆMIAACUTE HYPERCALCÆMIC SYNDROME DURING TREATMENT OF OSTEOPOROSIS WITH CALCIUM INFUSIONChronic vitamin A intoxication in adultsHautveränderungen bei Störungen des VitaminstoffwechselsPain in the Extremities, Dysesthesia, PolyalgiaHypervitaminosis ADie Pathologie der Avitaminosen und HypervitaminosenVitamin A Intoxication in Adults 1 July 1953Volume 39, Issue 1Page: 131-134KeywordsChildrenDrugsInfantsIngestionLiverVitamin AYoung adults ePublished: 1 December 2008 Issue Published: 1 July 1953 PDF downloadLoading ...