CLINICO-PATHOLOGIC OBSERVATIONS ON INFANTILE PARALYSIS: REPORT OF 125 ACUTE CASES WITH SPECIAL REFERENCE TO THE THERAPEUTIC USE OF CONVALESCENT AND ADULT BLOOD TRANSFUSIONS: THE POSSIBLE RELATION OF BLOOD GROUP TO THE SEVERITY OF THE DISEASE
Authors: D. Murray Cowie, J. P. Parsons, K. Lowenberg
Journal: Annals of Internal Medicine (1934)

Article1 November 1934CLINICO-PATHOLOGIC OBSERVATIONS ON INFANTILE PARALYSIS: REPORT OF 125 ACUTE CASES WITH SPECIAL REFERENCE TO THE THERAPEUTIC USE OF CONVALESCENT AND ADULT BLOOD TRANSFUSIONS: THE POSSIBLE RELATION OF BLOOD GROUP TO THE SEVERITY OF THE DISEASED. MURRAY COWIE, M.D., F.A.C.P., J. P. PARSONS, M.D., K. LOWENBERG, M.D.D. MURRAY COWIE, M.D., F.A.C.P., J. P. PARSONS, M.D., K. LOWENBERG, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-8-5-521 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptDuring the Michigan infantile paralysis epidemic of 1931 (figure 1) 125 cases came under our observation. Eighty-one of these were first seen in the so-called systemic or pre-paralytic stage, 44 in the paralytic stage. All of the systemic cases received either convalescent poliomyelitis serum, convalescent whole blood, adult whole blood or a combination of these by the various administration routes. Four of these developed paralysis. One was not under our control and is omitted from the total number, leaving 80 treated cases for analysis. Seventy-seven of these, or 96 per cent, did not develop paralysis. In the three patients developing...Bibliography1. LUKSCHE A: Ein Fall von Poliomyelitis anterior, Verhandl. deutsch. Arzte Prag. Sitzung von 9.5, 1924. Google Scholar2. HAUPTLI O: Zur Histologie der Polioenz. acuta, Deutsch. Ztschr. f. Nervenheilk., 1921, lxxi, 1. Google Scholar3. WÖHRMANN W: Über Poliomyelitis anterior acuta, Virchow's Arch. f. path. Anat., 1926, cclix, 466-488. CrossrefGoogle Scholar4. CREUTZFELD HG: Zur Histopathologie der experimentellen Poliomyelitis acuta (Heine-Medin) beim Affen und Meerschweinchen, Ztschr. f. Hyg. u. Infektionskrankh., 1925, cv, 402-415. Google Scholar5. SHARPNELSON RGR: Bulbar type of acute poliomyelitis, Trans. Am. Neur. Assoc., 1922, cciii. Google Scholar6. THOMASLHERMITTE AJ: Les lésions cérébrales et médullaires de la poliomyélite aiguë de l'adulte, Rev. neurol., 1929, i, 1242-1250. Google Scholar7. HURST EW: Histology of experimental poliomyelitis, Jr. Path. and Bact., 1929, xxxii, 457-477. CrossrefGoogle Scholar8. STILL GF: Second attacks of acute poliomyelitis and minimal duration of immunity, Arch. Dis. Child., 1930, v, 295-298. CrossrefGoogle Scholar9. PEREMANS G: Attaques répéteés de paralysie infantile, Scalpel, 1923, lxxxvi, 1319. Google Scholar10. MARINESCODRAGANESCO GS: Un cas suraigu de la maladie de Heine-Medin, Ann. d'anat. path., 1928, v, 153-155. Google Scholar11. LÉCHELLEBARUKDOUADY PHD: Poliomyélite aiguë avec troubles sympathiques intenses ayant simulé une artérite oblitérante, Bull. et mém. Soc. méd. d. hôp. de Paris, 1927, li, 500-503. Google Scholar12. WERNSTEDT W: Klinische Studien über eine zweite grosse Poliomyelitis-Epidemie in Schweden 1911-1913, Ergebn. d. inn. Med. u. Kinderh., 1924, xxv, 705-820. Google Scholar13. RADOVICI A: La paralysie faciale épidémique au cours de l'épidémie actuelle de poliomyélite en Roumanie, Presse méd., 1928, xxxvi, 516. Google Scholar14. STERN W: Poliomyelitis unter dem Bilde isolierter Facialislähmung, Med. Klin., 1926, xxii, 1600. Google Scholar15. LUNDSGAARD KK: Einige Fälle von erworberner Augenmuskellähmung bei Kindern (Poliomyelitis anterior, Heine-Medin-Krankheit), Klin. Monatblt. f. Augenh., 1912, ii, 734-739. Google Scholar16. NEMLICHER L: Zur Charakteristic der Epidemie der Heine-Medin Krankheit in Charkow im Herbst 1924. Google Scholar17. BUGBEE HG: Paralysis of bladder with acute poliomyelitis, Jr. Urol., 1925, xiii, 333-335. CrossrefGoogle Scholar18. MENDEL K: Poliomyelitis chronica lateralis, Neurol. Zentralbl., 1916, xxxv, 694. Google Scholar19. COMFORT MW: Chronic anterior poliomyelitis with achondroplasia, Med. Clin. N. Am., 1925, viii, 1287-1293. Google Scholar20. STERLING W: Ungewohnliche trophische Storungen bei der Heine-Medin Krankheit, Polska Gaz. Lek., 1928, vii, 44. Google Scholar21. KENNEDY F: A case of acute epidemic poliomyelitis, Jr. Nerv. and Ment. Dis., 1912, xxxix, 558. CrossrefGoogle Scholar22. KOENIG W: Über die bei den cerebralen Kinderlähmungen zu beobachtenden Wachsthumsstörungen, Deutsch. Ztschr. f. Nervenh., 1900, xix, 63-86. CrossrefGoogle Scholar23. BOUTTIERVAN BOGAERT HL: A propos d'un cas anatomoclinique de poliomyélite infantile, Ann. de méd., 1923, xiv, 89-107. Google Scholar24. SPATZ H: Encephalitis, Handbuch der Geisteskrankheiten Herausgegeben von O. Bumke, Vol. 2, Part 7, page 157. Google Scholar25. MARINESCO G: De la transmission du virus de la Poliomyélite par des nerfs périphériques et ses rapports avec les infections ascendantes, Compt. rend. Soc. de biol., 1911, lxx, 286-288. Google Scholar26. HURST EW: Further contribution to pathogenesis of experimental poliomyelitis; inoculation into sciatic nerve, Jr. Path. and Bact., 1930, xxxiii, 1133-1143. CrossrefGoogle Scholar27. JUNGEBLUTSPRING CWWJ: Note on propagation of virus in experimental poliomyelitis, Proc. Soc. Exper. Biol. and Med., 1930, xxvii, 1076-1078. CrossrefGoogle Scholar28. FLEXNERPEABODYDRAPER SFG: Epidemic poliomyelitis; twelfth note: the visceral lesions of human cases, Jr. Am. Med. Assoc., 1912, lviii, 109-111. CrossrefGoogle Scholar29. AYCOCKKAGAN WLJR: Experimental immunization in poliomyelitis Jr. Immunol., 1927, xiv, 85; abstr. Jr. Am. Med. Assoc., 1927, lxxxix, 1638. Google Scholar30. MCEACHERNBELL JMLG: Lessons from poliomyelitis epidemic in Manitoba, 1928, Canad. Public Health Jr., 1929, xx, 427-430. Google Scholar31. SHAWTHELANDERLIMPER EBHEMA: Treatment of poliomyelitis, Jr. Am. Med. Assoc., 1931, xcvii, 1620-1624. CrossrefGoogle Scholar32. AYCOCKLUTHER WLEH: Preparalytic poliomyelitis, observations in 106 cases in which convalescent serum was used, Jr. Am. Med. Assoc., 1928, xci, 387-394. CrossrefGoogle Scholar33. LOMERSHIRREFF TAWT: Report on epidemic of poliomyelitis in Ottawa, 1929, Canad. Med. Assoc. Jr., 1930, xxii, 228-234. Google Scholar34. AMOS HL: Poliomyelitis, Southern Med. Jr., 1930, xxiii, 18-21. Google Scholar35. PARK WH: Therapeutic use of anti-poliomyelitis serum in preparalytic cases of poliomyelitis, Jr. Am. Med. Assoc., 1932, xcix, 1050-1053. CrossrefGoogle Scholar36. GODFREY EL: Jr. Am. Med. Assoc., 1927, lxxxix, 23, 1925. Google Scholar37. WEED LH: Cerebrospinal fluid, Physiol. Rev., 1922, ii, 171-203. CrossrefGoogle Scholar38. WEED LH: Studies on cerebrospinal fluid, Jr. Med. Res., 1914, xxvi, 21-111. Google Scholar39. JUNGEBLUT CW: Power of normal human sera to inactivate virus of poliomyelitis in its relation to blood grouping and to exposure, Jr. Immunol., 1933, xxiv, 157. Google Scholar40. Unpublished report of the Michigan Commission on Infantile Paralysis, 1931, 615 State Office Bldg., Lansing, Michigan. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Ann Arbor, Michigan*Presented at the meeting of the American Pediatric Society at Rochester, Minnesota, May 1932.From the Departments of Pediatrics and Infectious Diseases, and Psychiatry, University Hospital, University of Michigan, Ann Arbor, Michigan. Nextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byHistory of Poliomyelitis and Poliomyelitis ResearchAllgemeine Pathologie der VirusinfektionenMyokarditis und weitere MyokardiopathienHerz- und Kreislaufstörungen bei InfektionskrankheitenHerz- und Kreislaufstörungen bei InfektionskrankheitenCardiovascular Disturbances in PoliomyelitisSignificance of potassium depletion in poliomyelitisELECTROCARDIOGRAPHIC CHANGES IN ACUTE POLIOMYELITIS IN CHILDHOODCardiovascular Manifestations in Acute PoliomyelitisMyocarditis in poliomyelitisHuman Serum: Its Application in MedicineComments 1 November 1934Volume 8, Issue 5Page: 521-551KeywordsBloodBlood groupsBlood transfusionInfectious diseasesNursesParalysisPoliomyelitisRoutes of administration ePublished: 1 December 2008 Issue Published: 1 November 1934 PDF downloadLoading ...