Fulminating Staphylococcal Infections Treated with Fucidin⌖ and Penicillin or Semisynthetic Penicillin
Authors: KLAUS JENSEN
Journal: Annals of Internal Medicine (1964)

Article1 May 1964Fulminating Staphylococcal Infections Treated with Fucidin⌖ and Penicillin or Semisynthetic PenicillinKLAUS JENSEN, M.D., H. C. A. LASSEN, M.D.KLAUS JENSEN, M.D.Search for more papers by this author, H. C. A. LASSEN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-60-5-790 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe treatment of fulminating staphylococcal infection is still a great problem in spite of the rapid development of chemotherapy. This is mainly due to three factors: [1] the ability of staphylococci to become chemoresistant during treatment, [2] the rapid course of staphylococcal infection that makes patients extremely ill before a diagnosis can be established and, therefore, having only a short time left for chemotherapy, and [3] extensive focal lesions with pus and necrotic tissue that delays and restricts the activity of the antibiotics and favors the development of bacterial resistance.The good results obtained with the new semisynthetic penicillins unaffected...References1. DICKINSONPRIDE JMNB: Treatment of staphylococcal infections with methicillin. Brit. Med. J. 1: 432, 1962. CrossrefMedlineGoogle Scholar2. JEVONS MP: "Celbenin"-resistant staphylococci. Brit. Med. J. 1: 124, 1961. CrossrefGoogle Scholar3. STEWARTHOLT GTRJ: Evolution of natural resistance to the newer penicillins. Brit. Med. J. 1: 308, 1963. CrossrefMedlineGoogle Scholar4. 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Author, Article, and Disclosure InformationAffiliations: Copenhagen, DenmarkFrom the University Clinic for Infectious Diseases, Blegdamshospitalet, Copenhagen, Denmark.Requests for reprints should be addressed to Klaus Jensen, M.D., Chief, Clinical Microbiology, University Hospital for Infectious Diseases, Blegdamshospitalet, Copenhagen, Denmark. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByFusidic AcidSuccessful Management of an Infected Implantable Cardioverter Defibrillator with Oral Antibiotics and without Removal of the DeviceAntibiotic Sensitivity of Staphylococcus Aureus. Past and PresentAdverse Reactions to Intravenous Administration of Fusidic AcidStaphylococcal bacteraemia, fusidic acid, and jaundice.Chemotherapy of Brain AbscessThe classic bacterial pneumoniasAspectos gerais das septicemias e bacteriemias estafilocócicas no adultoSTAPHYLOCOCCAL ENDOCARDITIS TREATED BY INTRAVENOUS ADMINISTRATION OF FUSIDIC ACID AND PENICILLIN 1 May 1964Volume 60, Issue 5Page: 790-798KeywordsAntibioticsChemotherapyInfectious diseasesLesionsPenicillinStaphylococcal infectionStaphylococcus aureus Issue Published: 1 May 1964 PDF DownloadLoading ...