ACUTE FEBRILE ANEMIA AND THROMBOCYTOPENIC PURPURA WITH VASOTHROMBOSES
Authors: G L ENGEL, I M SCHEINKER, D C HUMPHREY
Journal: Annals of Internal Medicine (1947)

Case Reports1 June 1947ACUTE FEBRILE ANEMIA AND THROMBOCYTOPENIC PURPURA WITH VASOTHROMBOSESGEORGE L. ENGEL, M.D., I. MARK SCHEINKER, M.D., DAVID C. HUMPHREY, M.D.GEORGE L. ENGEL, M.D., I. MARK SCHEINKER, M.D., DAVID C. HUMPHREY, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-26-6-919 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAn acute syndrome, characterized clinically by fever, anemia, thrombocytopenic purpura, renal, cardiac, and neurological manifestations, and pathologically by thrombotic lesions occluding arterioles, capillaries, and venules in almost every organ and tissue, was described by Baehr, Klemperer and Schifrin in 1936.1Moschcowitz2described a case with similar pathological finding but without purpura in 1925. To date only seven cases have been recorded in the literature, five from the Mt. Sinai Hospital in New York.1, 2, 3, 4, 5This number from one hospital suggests that the disease is a good deal more common than the literature would indicate, and that it...Bibliography1. BAEHRKLEMPERERSCHIFRIN GPA: Acute febrile anemia and thrombocytopenic purpura with platelet thromboses in capillaries and arterioles, Trans. Assoc. Am. Phys., 1936, li, 43. Google Scholar2. MOSCHCOWITZ E: An acute febrile pleiochromic anemia with hyaline thromboses of the terminal arterioles and capillaries, Arch. Int. Med., 1925, xxxvi, 89. CrossrefGoogle Scholar3. FRIEDBERGGROSS CKL: Non-bacterial thrombotic endocarditis associated with acute thrombocytopenic purpura, Arch. Int. Med., 1936, lviii, 641. CrossrefGoogle Scholar4. ALTSCHULE MD: A rare type of acute thrombocytopenic purpura: widespread formation of platelet thrombi in capillaries, New England Jr. Med., 1942, ccxxvii, 477. CrossrefGoogle Scholar5. BERNHEIM AI: Widespread capillary and arteriolar platelet thrombi, Jr. Mt. Sinai Hosp., 1943, x, 287. Google Scholar6. KLEMPERER P: Personal communication. Google Scholar7. LIBMAN E: Some aspects of Libman-Sacks disease, Jr. Mt. Sinai Hosp., 1942, ix, 621. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication April 30, 1946.From the Departments of Medicine and Pathology and the Laboratory of Neuropathology, College of Medicine, University of Cincinnati. 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