XANTHOMATOUS BILIARY CIRRHOSIS: REPORT OF A CASE
Authors: G F ROBERTSON, G CARTER
Journal: Annals of Internal Medicine (1952)

Case Reports1 May 1952XANTHOMATOUS BILIARY CIRRHOSIS: REPORT OF A CASEGORDON F. ROBERTSON, M.D., GRAY CARTER, M.D.GORDON F. ROBERTSON, M.D.Search for more papers by this author, GRAY CARTER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-36-5-1336 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptWhen cutaneous xanthomatosis is associated with obstructive jaundice, unless a metastatic process is proved, an exploratory laparotomy seems to be indicated. If there is an enlargement of the liver and spleen with a high blood cholesterol and hyperlipemia, the so-called xanthomatous biliary cirrhosis must be considered.According to Fuentes1 and Romano,2 this condition can be recognized clinically by means of the hypercholesterolemia and ether-extractible bilirubin, and surgery can thus be avoided.If surgical exploration is carried out, however, and no surgically-removable lesion is found, a biopsy of the liver is in order. One would expect, as Thannhauser and Magendantz3did,...Bibliography1. FuentesMiqueoMedocDe Piguel BVMJAR: New humoral signs for the early diagnosis of xanthomatous biliary cirrhosis, Prensa med. Argent. 32: 2559 (Dec.) 1945. MedlineGoogle Scholar2. Romano N: Diabetes mellitus and xanthomatous cirrhosis, Prensa med. Argent. 34: 433 (Mar.) 1947. MedlineGoogle Scholar3. ThannhauserMagendantz SJH: The differential clinical groups of xanthomatous diseases; a clinical physiological study of 22 cases, Ann. Int. Med. 11: 1662-1746 (Mar.) 1938. LinkGoogle Scholar4. MacMahon HE: Biliary xanthomatosis (xanthomatous biliary cirrhosis), Am. J. Path. 24: 527-533 (May) 1948. MedlineGoogle Scholar5. Montgomery H: Xanthomatosis (cutaneous xanthoma, especially in relation to diseases of the liver), J. Invest. Dermat. 1: 325-351, 1938. CrossrefGoogle Scholar6. Alvoord RM: Coronary heart disease and xanthoma tuberosum associated with hereditary hyperlipemia, Arch. Int. Med. 84: 1002-1019 (Dec.) 1949. CrossrefGoogle Scholar7. PollardEcksteinRansom HMHCHK: The effect of lipotropic substances and external biliary drainage on xanthomatous biliary cirrhosis, Proc. Am. Federation Clin. Research 2: 44, 1945. MedlineGoogle Scholar8. HuberBrownCasey MJGOAE: Prevention of cholesterol arteriosclerosis in the rabbit by use of pancreatic extract (lipocaic), Proc. Soc. Exper. Biol. and Med. 37: 441-445 (Dec.) 1937. CrossrefGoogle Scholar9. Dragstedt LR: Lipocaic; new pancreas hormone, Northwest Med. 37: 33-36 (Feb.) 1938. Google Scholar10. ComfortShepardSnell MWVDAM: Xanthomatous biliary cirrhosis: report of a case, Proc. Staff Meet., Mayo Clin. 16: 374-377 (June) 1941. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Greenwich, Connecticut*Received for publication July 22, 1950. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byXanthomatous Biliary Cirrhosis in the MaleDie angeborenen Stoffwechselanomalien des Menschen 1 May 1952Volume 36, Issue 5Page: 1336-1343KeywordsBiopsyBloodCirrhosisHypercholesterolemiaHyperlipidemiaLaparotomyLesionsLiverSpleenSurgery ePublished: 1 December 2008 Issue Published: 1 May 1952 PDF downloadLoading ...