GENERALIZED SCLEREDEMA: REPORT WITH AUTOPSY FINDINGS
Authors: I LEINWAND
Journal: Annals of Internal Medicine (1951)

Case Reports1 January 1951GENERALIZED SCLEREDEMA: REPORT WITH AUTOPSY FINDINGSIRVING LEINWAND, M.D.IRVING LEINWAND, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-34-1-226 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSince Buschke1 in 1900 described the syndrome designated as scleredema adultorum there have been 99 cases reported in the literature collected and reviewed by Vallee,2 to which he added four. One autopsied case had been reported by Stenbeck3 (1940), in which he noted visceral lesions resembling those found in the skin. In view of the overwhelming preponderance of recoveries in this disease, some doubts have been expressed as to the diagnosis of a true scleredema in that case: although the clinical picture resembled scleredema, a review of the pathologic report suggests a diagnosis of scleroderma.The systemic nature of scleredema...Bibliography1. Buschke A: Vorstellung eines Falles von Skleroedem vor der Berliner Gesellschaft für Dermatologie, Arch. f. Dermat. u. Syph. 53: 383, 1900. Google Scholar2. Vallee BL: Scleredema: a systemic disease, New England J. Med. 235: 207-213, 1946. CrossrefMedlineGoogle Scholar3. Stenbeck A: Ueber einen Fall von Skleroedem mit Augenveränderungen, Acta ophth. 18: 76-84, 1940. CrossrefGoogle Scholar4. Voss : Skleroedema adultorum Buschke, Zentralbl. f. Haut- u. Geschlechtskr. 59: 248, 1938. Google Scholar5. O'LearyWaismanHarrison PAMMW: Scleredema adultorum, Am. J. M. Sc. 199: 458-466, 1940. CrossrefGoogle Scholar6. Schnitzer A: Ueber zwei Fälle von Skleroedema adultorum, Dermatologica 84: 215-224, 1941. CrossrefGoogle Scholar7. Personal communication. Google Scholar8. Selye H: Effect of Estradiol locally applied to abnormal skin, Arch. Dermat. and Syph. 48: 188-192, 1943. CrossrefGoogle Scholar9. Selye H: Effect of folliculoid hormones and abnormal skin, Arch. Dermat. and Syph. 50: 261-263, 1944. CrossrefGoogle Scholar10. Fish H: Scleroderma associated with juvenile rheumatism, London County Council, Ann. Report 1930-32, vol. 4, pt. 3, p. 10. Google Scholar11. Epstein NN: Scleredema adultorum (Buschke) J. A. M. A. 99: 820-826, 1932. CrossrefGoogle Scholar12. Wieneer : Skleroedem und Zungenveränderung im Verlaufe eines Falles von perniziöser Anämie, Zentralbl. f. Haut- u. Geschlechtskr. 17: 268, 1925. Google Scholar13. Frank LJ: Scleredema adultorum (Buschke): report of case involving tongue, Arch. Dermat. and Syph. 36: 1052, 1937. CrossrefGoogle Scholar14. SweitzerLaymon SECW: Scleredema adultorum (Buschke), Arch. Dermat. and Syph. 37: 420-430, 1938. CrossrefGoogle Scholar15. Klemperer P: Diseases of the collagen system, New York Acad. Med. 10: 581-588 (October) 1947. Google Scholar16. Bevans M: Pathology with special reference to changes in the gastrointestinal tract, Am. J. Path. 21: 25 (Jan.) 1945. MedlineGoogle Scholar17. Goetz RH: The pathology of progressive systemic sclerosis (generalized scleroderma), Clin. Proc. 4: 337-392 (Aug.) 1945. Google Scholar18. LeinwandDuryee IAW: Scleroderma: diffuse disease of the collagen system, report of 145 cases (to be published). Google Scholar19. TouraineGoleSoulignac ALRR: La cellulite sclerodermiforme extensive bénigne. Scléroedème de Buschke, Ann. de dermat. et syph. 8: 761-800, 1937. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Received for publication April 22, 1948. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byScleredema with biopsy-confirmed cardiomyopathy: A case reportHistoria del compromiso cutáneo de la esclerosis sistémicaJuvenile Scleredema of BuschkeCharacteristics of Interstitial Fibrosis and Inflammatory Cell Infiltration in Right Ventricles of Systemic Sclerosis-Associated Pulmonary Arterial HypertensionThe Heart in SclerodermaScleredema associated with paraproteinaemia treated by extracorporeal photopheresisSystemic involvement in scleredema of Buschke associated with IgG-kappa paraproteinaemiaScleredema RevisitedA fatal case of scleredema of BuschkeThe cutaneous mucinosesScleredema: A review of thirty-three casesROYAL SOCIETY OF MEDICINE.Dermatomyositis and Focal SclerodermaAblagerungskrankheiten körpereigener StoffwechselprodukteAn Historical Account of the Study of Progressive Systemic Sclerosis (Diffuse Scleroderma)GERALD P. RODNAN, M.D., THOMAS G. BENEDEK, M.D.Focal sclerodermaMyokarditis und weitere MyokardiopathienScleredema (Buschke) 1 January 1951Volume 34, Issue 1Page: 226-238KeywordsAutopsyLesionsScleroderma ePublished: 1 December 2008 Issue Published: 1 January 1951 PDF downloadLoading ...