ARTERIOSCLEROSIS AND HYPERTENSION IN DIABETES
Authors: Howard F. Root, Thomas P. Sharkey
Journal: Annals of Internal Medicine (1936)

Article1 January 1936ARTERIOSCLEROSIS AND HYPERTENSION IN DIABETESHOWARD F. ROOT, M.D., F.A.C.P., THOMAS P. SHARKEY, M.D.HOWARD F. ROOT, M.D., F.A.C.P., THOMAS P. SHARKEY, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-9-7-873 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThat arteriosclerosis occurs in excessive degree in diabetic patients has found general acceptance among American students. The importance of characteristic metabolic changes of diabetes in its causation was pointed out in the first study of Deaconess Hospital autopsy data by Root and Warren.1Further reports by Joslin2emphasized the clinical significance of arteriosclerotic complications of diabetes, and Warren3summarized the pathologic data bearing upon arteriosclerosis in a large series of diabetics. Other aspects of this problem require investigation, such as (1) when does the excessive arteriosclerosis found in diabetic patients develop? (2) what are the characteristic steps in its progress?...References1. ROOTWARREN HFS: A clinical and pathologic study of 26 cases of diabetes, Boston Med. and Surg. Jr., 1926, cxciv, 145-153. Google Scholar2. JOSLIN EP: Arteriosclerosis in diabetes, ANN. INT. MED., 1930, iv, 54-66. Google Scholar3. WARREN S: The pathology of diabetes mellitus, 1930, Lea and Febiger, Philadelphia, p. 119. Google Scholar4. PINCUSJOSLINWHITE GEPP: The age-incidence relations in diabetes mellitus, Am. Jr. Med. Sci., 1934, clxxxviii, 116. CrossrefGoogle Scholar5. BELLCLAWSON GTBJ: Primary (essential) hypertension; study of 420 cases, Arch. Path., 1928, v, 939-1002. Google Scholar6. MAJOR S: Blood pressure in diabetes mellitus, a statistical study, Arch. Int. Med., 1929, xliv, 797. CrossrefGoogle Scholar7. WILLIUSSMITHSPRAGUE : A study of coronary and aortic sclerosis, incidence and degree in 5060 consecutive postmortem examinations, Proc. Staff Meet., Mayo Clinic, 1933, viii, 140. Google Scholar8. LEHNHERR E: Arteriosclerosis and diabetes mellitus, N. Eng. Jr. Med., 1933, ccviii, 1307. CrossrefGoogle Scholar9. WAGENERDRYWILDER : Retinitis in diabetes, N. Eng. Jr. Med., 1934, ccxi, 1131. CrossrefGoogle Scholar10. WAITEBEETHAM JHWC: The visual mechanism in diabetes mellitus (a comparative study of 2002 diabetics, and 457 non-diabetics for control), N. Eng. Jr. Med., 1935, ccxii, 367. CrossrefGoogle Scholar11. MURPHYGRILLPESSINMOXON : Essential (primary) hypertension; clinical and morphological study of 375 cases, ANN. INT. MED., 1932, i, 31. Google Scholar12. O'HAREWALKERVICKERS JPWGMD: Heredity and hypertension, Jr. Am. Med. Assoc., 1924, lxxxiii, 27-28. CrossrefGoogle Scholar13. WEITZ : Zur Aetiologie der genuinen oder vasculären Hypertension, Ztschr. f. klin. Med., 1923, xcvi, 151-181. Google Scholar14. BENEDICTROOT : The physiology of extreme old age, N. Eng. Jr. Med., 1934, ccxi, 521. CrossrefGoogle Scholar15. PINCUSWHITE GP: On the inheritance of diabetes mellitus. II. Further analysis of family histories, Am. Jr. Med. Sci., 1934, clxxxviii, 159. CrossrefGoogle Scholar16. ALVAREZNEUSCHLOSZ : Untersuchungen über das Blutcholesterin bei arteriellem Hochdruck, Klin. Wchnschr., 1931, x, 244. CrossrefGoogle Scholar17. LEARY : Experimental atherosclerosis in rabbit compared with human (coronary) atherosclerosis, Arch. Path., 1934, xvii, 453-492. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Boston, Massachusetts*Read at the Philadelphia meeting of the American College of Physicians, May 3, 1935.From the George F. Baker Clinic, Elliott P. Joslin, Medical Director, New England Deaconess Hospital, Boston, Massachusetts. 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