THROMBOCYTOPENIC PURPURA AND CARCINOMA OF STOMACH; REPORT OF A CASE WITH PURPURA APPEARING AFTER SUBTOTAL GASTRECTOMY
Authors: Willard H. Willis
Journal: Annals of Internal Medicine (1942)

Case Reports1 April 1942THROMBOCYTOPENIC PURPURA AND CARCINOMA OF STOMACH; REPORT OF A CASE WITH PURPURA APPEARING AFTER SUBTOTAL GASTRECTOMYWILLARD H. WILLIS, M.D.WILLARD H. WILLIS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-16-4-782 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIsolated instances of thrombopenia and purpura associated with carcinoma of the stomach have previously been reported. These cases are of diagnostic interest because the clinical picture is frequently confusing. The initial complaint may be referable to the purpura, and the gastrointestinal symptoms, if present, may be ignored by the patient and the physician. The primary lesion may be small and difficult to diagnose by roentgen-ray as well as at the autopsy table. Even if carcinoma is suspected the characteristically extensive metastatic invasion of the bone marrow and lungs may not be discernible in roentgenograms.In 1936 Jarcho11called attention to...Bibliography1. SCHLEIP K: Zur Diagnose von Knochenmarkstumoren aus dem Blutbefunde, Ztschr. f. klin. Med., 1906, lviv, 261-282. Google Scholar2. DÜNNER L: Perniziöse Anämie und Karzinom, Berl. klin. Wchnschr., 1921, lviii, 386-388. Google Scholar3. DÜNNER L: Zur Aetiologie der Thrombopenie, Berl. klin. Wchnschr., 1921, lviii, 1107. Google Scholar4. SEEMANNKRASNOPOLSKI GA: Akut "Leukanämie" mit starker extramedullärer Blutbildung als Folge ausgedehnter Knochenmarksverdrängung durch Magenkrebsmetastasen. (Zugleich ein Beitrag zur Kenntnis der diffus infiltrierenden Carcinome), Virchow's Arch. f. path. Anat., 1926, cclxii, 697-711. CrossrefGoogle Scholar5. BLUM K: Über symptomatische Thrombopenie bei Magencarcinom. (Ein Beitrag zur Pathogenese der hämorrhagischen Diathesen), Med. Klin., 1928, xxiv, 1200-1202. Google Scholar6. STEINFIELDSHAY EH: Gastric carcinoma complicated by thrombocytopenic purpura, Med. Clin. North Am., 1930, xiii, 923-929. Google Scholar7. KOHN E: Symptomatische Thrombopenie bei malignen Tumoren des Knochenmarkes, Med. Klin., 1931, xxvii, 767-768. Google Scholar8. STILLMAN RG: Coincidence of malignant tumor and purpura hemorrhagica, Med. Clin. North Am., 1931, xiv, 1533-1538. Google Scholar9. LAWRENCEMAHONEY JSEB: Thrombopenic purpura associated with carcinoma of stomach with extensive metastasis, Am. Jr. Path., 1934, x, 383-390. Google Scholar10. STEBBINSCARNS GGML: Thrombocytopenic purpura associated with adenocarcinoma of stomach in young adult, Arch. Path., 1935, xx, 247-252. Google Scholar11. JARCHO S: Diffusely infiltrative carcinoma; hitherto undescribed correlation of several varieties of tumor metastasis, Arch. Path., 1936, xxii, 674-696. Google Scholar12. MCLEODGOODALE CERH: Adenocarcinoma of stomach with hemorrhagic diathesis, New York State Jr. Med., 1938, xxxviii, 1339-1341. Google Scholar13. THOMPSONILLYNE WPCA: Clinical and hematologic picture resulting from bone marrow replacement, Med. Clin. North Am., 1940, xxiv, 841-853. CrossrefGoogle Scholar14. NAEGELI O: Blutkrankheiten und Blutdiagnostik, 1931, Julius Springer, Berlin, p. 661. CrossrefGoogle Scholar15. SCHATTENBERGRYAN HJJF: Lymphangitic carcinomatosis of the lungs; case report with autopsy findings, ANN. INT. MED., 1941, xiv, 1710-1721. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Utica, New York*Received for publication April 26, 1941. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byOccurrence of immune thrombocytopenic purpura in patients with nonhematologic cancers: a systematic review of clinical evidence from case reportsSome Peculiar Clinical Pictures in Metastasizing Carcinoma of the StomachNeurological Complications of Bronchial CarcinomaTHE ROYAL CHEST HOSPITAL 1 April 1942Volume 16, Issue 4Page: 782-787KeywordsAutopsyBone marrowGastrectomyLesionsLungsStomachThrombocytopenia Issue Published: 1 April 1942 PDF downloadLoading ...