ADDISON'S DISEASE SECONDARY TO METASTATIC CARCINOMA OF THE ADRENAL GLANDS
Authors: J M BUTTERLY, L FISHMAN, J SECKLER, H STEINBERG
Journal: Annals of Internal Medicine (1952)

Article1 November 1952ADDISON'S DISEASE SECONDARY TO METASTATIC CARCINOMA OF THE ADRENAL GLANDSJOHN M. BUTTERLY, M.D., LOUIS FISHMAN, M.D., JULES SECKLER, M.D., HERMAN STEINBERG, M.D.JOHN M. BUTTERLY, M.D., LOUIS FISHMAN, M.D., JULES SECKLER, M.D., HERMAN STEINBERG, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-37-5-930 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSince Addison's classic and comprehensive description of the disease bearing his name,1, 2 accepted etiologic factors have included tuberculosis and cytotoxic contracted adrenals (atrophy) almost exclusively. Much less frequently, the disease has been ascribed to amyloidosis, fatty degeneration, syphilis, tumors, vascular lesions and trauma of the adrenals. Both glands are involved completely and extensively in almost all cases, although rare cases with unilateral destruction or aplasia have been reported.3A complete review of the literature reflects the widespread doubt cast on the mechanism of neoplastic destruction of the adrenals, more specifically by metastatic involvement, as a cause of adrenal cortical...Bibliography1. Addison T: Anemia—disease of the suprarenal capsule, London M. Gaz. 48: 517, 1849. Google Scholar2. Addison T: On the constitutional and local effects of disease of the suprarenal capsules. Reprinted in M. Classics 2: 244, 1937. Google Scholar3. Guttman PH: Addison's disease: statistical analysis of 566 cases and study of the pathology, Arch. Path. 10: 742, 895, 1930. Google Scholar4. PoyntonWrightLaurent FJGPLP: Clinical symptoms of Addison's disease occurring in course of pulmonary carcinoma, Lancet 1: 740, 1933. CrossrefGoogle Scholar5. AguilarBancalasi OPCA: Addison's disease due to metastatic cancer of the adrenals simulating grave tuberculosis, Arch. Argent. de tisiol. 16: 321, 1940. Google Scholar6. Madheim H: Rare organ carcinoses in patients with gastric carcinoma; case of Addison's disease due to adrenal metastases, Frankfurt. Ztschr. f. Path. 55: 447, 1941. Google Scholar7. Strang C: Addison's disease due to metastases from bronchogenic carcinoma, Newcastle M. J. 21: 126, 1942. Google Scholar8. RowntreeSnell LGAM: A clinical study of Addison's disease, 1931, W. B. Saunders Company, Philadelphia. Google Scholar9. Duffin JD: Cortical necrosis of the adrenal glands associated with Addison's disease, Arch. Path. 35: 649, 1943. Google Scholar10. Sorkin SZ: Addison's disease, Medicine 28: 371, 1949. CrossrefMedlineGoogle Scholar11. Soffer LJ: Diseases of the adrenals, 1946, Lea and Febiger, Philadelphia. Google Scholar12. RobinsonPowerKepler FSMHEJ: Two new procedures to assist in the recognition and exclusion of Addison's disease: a preliminary report, Proc. Staff. Meet., Mayo Clin. 16: 577, 1941. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication July 13, 1951.From the Departments of Medicine and Pathology, Queens General Hospital, Jamaica, N. Y. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byMetastatic Transitional Cell Carcinoma of the Bladder Causing Addison'S DiseaseAddison's disease secondary to lymphomatous infiltration of the adrenal glands recovery of adrenocortical function after chemotherapyAddison's disease due to metastases to the adrenal glands.Metastases to the adrenal glands and the development of Addison's diseaseAdrenal failure associated with hypothalamic and adrenal metastases: A case report and review of the literatureDie NebennierenrindeAddison's disease secondary to metastatic carcinoma: An example of adrenocortical and adrenomedullary insufficiencyAddison's disease secondary to occult metastatic seminoma:Infarction of the adrenals as the probable mechanism of their destructionAdrenal insufficiency due to metastatic carcinoma of the lung.Case report and review of addison's disease caused by adrenal metastasesUrinary porter-silber chromogens following intravenous methopyrapone and acth in patients with breast cancerAdrenocortical insufficiencyAdrenocortical Insufficiency Due to Metastatic Infiltration of the Adrenal GlandsAddison's Disease Secondary to Carcinoma of the BreastDAVID H. ALPERS, M.D., KARL ENGELMAN, M.D., F. DANIEL FOLEY, M.D.Haemochromatosis with Addison's DiseaseAddison's disease secondary to adrenocortical destruction by metastatic carcinoma of the breastADRENAL INSUFFICIENCY PRODUCED BY METASTASES FROM GASTRIC CARCINOMA*OLGA CUSHING LEARY JR., M.D., JACOB J. MASTERS, M.D.Clinical EndocrinologyManagement of Adrenocortical InsufficiencyMetastatic carcinoma to the adrenal glands with cortical hypofunction 1 November 1952Volume 37, Issue 5Page: 930-939KeywordsAdrenal glandsAmyloidosisAtrophyHospital medicineLesionsSyphilisVascular diseases Issue Published: 1 November 1952 PDF downloadLoading ...