Digoxin Pharmacokinetics in Continuous Peritoneal Dialysis
Authors: SALVADOR PANCORBO
Journal: Annals of Internal Medicine (1980)

Letters and Corrections1 October 1980Digoxin Pharmacokinetics in Continuous Peritoneal DialysisSALVADOR PANCORBO, PHARM, D., PH.D., CHRISTINA COMTY, M.D.SALVADOR PANCORBO, PHARM, D., PH.D.Search for more papers by this author, CHRISTINA COMTY, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-93-4-639_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: The weekly clearance of small and middle molecules in patients undergoing continuous ambulatory peritoneal dialysis has been shown to be higher than that in chronic intermittent peritoneal dialysis. Studies have shown clearances of vitamin B12 in patients undergoing continuous ambulatory peritoneal dialysis to be more than three times those reported for chronic intermittent peritoneal dialysis (1). Many patients undergoing continuous ambulatory peritoneal dialysis need digoxin for management of congestive heart failure or atrial arrhythmias. The clearance of digoxin in patients undergoing intermittent peritoneal dialysis has been reported to be about 8 mL/min (2). These values are considered...References1. POPOVICHMONCRIEFNOLPHGHODSTWARDOWSKIPYLE RJKAZW. Continuous ambulatory peritoneal dialysis. Ann Intern Med. 1978;88:449-56. LinkGoogle Scholar2. ACKERMANDOHERTYFLANIGAN GJW. Peritoneal dialysis and hemodialysis of tritiated digoxin. Ann Intern Med. 1967;67:718-23. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Hennepin County Medical Center Minneapolis, MN 55415 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDrug Administration and Pharmacogenomics in Children Receiving Acute or Chronic Renal Replacement TherapyGuidelines for Therapeutic Drug Monitoring of Cardiovascular Drugs Clinical Use of Blood Drug Concentration Monitoring (JCS 2015) ― Digest Version ―Extracorporeal treatment for digoxin poisoning: systematic review and recommendations from the EXTRIP WorkgroupDrug Use, Dosing, and Toxicity in Renal DiseaseDrug Administration and Pharmacogenomics in Children Receiving Acute or Chronic Renal Replacement TherapyPharmacological Alterations of Peritoneal Transport Rates and Pharmacokinetics in Peritoneal DialysisDrug Use and Dosage in Renal FailurePrinciples of drug administration in children receiving renal replacement therapyPharmacological alterations of peritoneal transport rates and pharmacokinetics in peritoneal dialysisPharmacologic alterations of peritoneal transport rates and pharmacokinetics of the peritoneumDComments on Dialysis Solution, Antibiotic Transport, Poisonings, and Novel Uses of Peritoneal DialysisPharmacological Considerations for Renal Failure and DialysisPharmacokinetic aspects during continuous ambulatory peritoneal dialysis: a literature reviewDrug Prescribing in Renal Failure: Dosing Guidelines for AdultsDrugs and Peritoneal DialysisPharmacological Aspects of Renal Failure and DialysisThe Peritoneal Handling of Digoxin during CAPD 1 October 1980Volume 93, Issue 4Page: 639-639KeywordsArrhythmiaHeart failurePeritoneal dialysisPharmacokinetics ePublished: 1 December 2008 Issue Published: 1 October 1980 PDF downloadLoading ...