The Vital Hormone of the Adrenal Cortex
Authors: Frank A. Hartman, Byron D. Bowen, Geo. W. Thorn, Clayton W. Greene
Journal: Annals of Internal Medicine (1931)

Article1 November 1931The Vital Hormone of the Adrenal CortexFRANK A. HARTMAN, A.M.,Ph.D., BYRON D. BOWEN, M.D., F.A.C.P., GEO. W. THORN, M.D., CLAYTON W. GREENE, M.D., F.A.C.P.FRANK A. HARTMAN, A.M.,Ph.D., BYRON D. BOWEN, M.D., F.A.C.P., GEO. W. THORN, M.D., CLAYTON W. GREENE, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-5-5-539 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIt has been known for many years that the adrenal glands are essential to life; but Wheeler and Vincent were the first to prove, at least in mammals, that the medulla was not essential. They found that as long as an adequate amount of cortex survived, destruction of all of the medullary tissue led to no ill effects.The next step in the study of the cortex was the preparation of an extract containing the hormone. The cortex contains a sufficient amount of epinephrin to make the removal of the latter necessary, especially if the extract is to be concentrated....Bibliography HARTMANAARONCULP FAAHJE: The use of cortin in Addison's disease, Endocrinology, 1930, xiv, 438. CrossrefGoogle Scholar HARTMANBROWNELL FAKA: The hormone of the adrenal cortex, Proc. Soc. Exp. Biol. and Med., 1930, xxvii, 938. CrossrefGoogle Scholar HARTMANBROWNELLHARTMAN FAKAWE: A further study of the hormone of the adrenal cortex, Am. Jr. Physiol., 1930, xcv, 670. CrossrefGoogle Scholar HARTMANMACARTHURHARTMAN FACGWE: A substance which prolongs the life of adrenalectomized cats, Proc. Soc. Exp. Biol. and Med., 1927, xxv, 69. CrossrefGoogle Scholar HARTMANSCOTT FAWJ: Protection of adrenalectomized animals against bacterial intoxication, Proc. Soc. Exp. Biol. and Med., 1931, xxviii, 478. CrossrefGoogle Scholar PERLAMARMORSTON-GOTTESMAN DJ: Effect of injections of cortin on resistance of suprarenalectomized rats, Proc. Soc. Exp. Biol. and Med., 1931, xxviii, 475. CrossrefGoogle Scholar ROGOFFSTEWART JMGN: The influence of adrenal extracts on the survival period of adrenalectomized dogs, Sci., 1927, lxvi, 327. CrossrefGoogle Scholar ROGOFFSTEWART JMGN: Suprarenal cortical extracts in suprarenal insufficiency, Jr. Am. Med. Assoc., 1929, xcii, 1569-1571. CrossrefGoogle Scholar ROWNTREEGREENESWINGLEPFIFFNER LGCHWWJJ: Addison's disease, Jr. Am. Med. Assoc., 1931, xcvi, 231. CrossrefGoogle Scholar SHAPIROMARINE SD: Clinical report of a case of Graves' disease with rapid improvement following the oral administration of fresh ox suprarenal gland, Endocrinology, 1921, v, 699. CrossrefGoogle Scholar SWINGLEPFIFFNER WWJJ: An aqueous extract of the suprarenal cortex which maintains the life of bilaterally adrenalectomized cats, Sci., 1930, lxxi, 321. CrossrefGoogle Scholar WHEELERVINCENT TDS: The question of the relative importance to life of cortex and medulla of the adrenal bodies, Trans. Roy. Soc. Canada, 1917, xi, 125. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *From the Departments of Physiology and of Medicine, University of Buffalo, Buffalo, N. Y.†Presented at the Baltimore meeting of the American College of Physicians, March 26, 1931. Nextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byForewordA Study of the Metabolism in Addison's Disease. IIInnere Sekretion 1 November 1931Volume 5, Issue 5Page: 539-551KeywordsAdrenal glandsHormones ePublished: 1 December 2008 Issue Published: 1 November 1931 PDF downloadLoading ...