SEVERE PYELONEPHRITIS DUE TO FRIEDLÄNDER'S BACILLUS TREATED SUCCESSFULLY WITH STREPTOMYCIN
Authors: P FISHER
Journal: Annals of Internal Medicine (1951)

Case Reports1 November 1951SEVERE PYELONEPHRITIS DUE TO FRIEDLÄNDER'S BACILLUS TREATED SUCCESSFULLY WITH STREPTOMYCINPETER FISHER, M.D.PETER FISHER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-35-5-1117 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptUrinary infections caused by Friedländer's bacillus (Bacillus mucosus capsulatus, Klebsiella pneumoniae) are not rare. Baehr, Schwartzman and Greenspan1 reported 50 cases in 1937. Review of the medical literature since that date has disclosed little mention of this disease25 until the advent of the use of streptomycin. Harris et al.10 in 1947 reported 21 cases of pyelonephritis treated with streptomycin, five of these due to the Friedländer bacillus. Of these, two were considered cured, one temporarily improved and two unimproved. Kleinman and his associates16 have also reported therapeutic failures with streptomycin in this disease.The author considers the following case of...Bibliography1. BaehrSchwartzmanGreenspan GGEB: Bacillus friedländer infections, Ann. Int. Med. 10: 1788, 1937. LinkGoogle Scholar2. BauerFreyberg JMRH: Vitamin D intoxication with metastatic calcification, J. A. M. A. 130: 1208-1215, 1946. CrossrefMedlineGoogle Scholar3. Boyd W: A textbook of pathology, 4th ed., 1943, Lea and Febiger, Philadelphia. Google Scholar4. Clawater E: Personal communication. Google Scholar5. Ezickson WJ: The value of sulfanilamide in the treatment of infections of bladder and upper urinary tract—report of a study of 25 patients, Ann. Int. Med. 12: 244-248, 1938. LinkGoogle Scholar6. FeinstoneWilliamsWolffHuntingtonCrossley WHRDMSENL: The toxicity, absorption and chemotherapeutic activity of 2-sulfanilamide-pyrimidine (sulfadiazine), Bull. Johns Hopkins Hosp. 67: 427, 1940. Google Scholar7. FergusonHershey CTS: Streptomycin in genito-urinary infections, J. Urol. 57: 932-937, 1947. CrossrefMedlineGoogle Scholar8. Greenspan EM: Hyperchloremic acidosis and nephrocalcinosis, Arch. Int. Med. 83: 271-291, 1949. CrossrefGoogle Scholar9. GrossCooperLewis PFBM: Sulfanilamide therapy of Friedländer-bacillus infections of mice, Proc. Soc. Exper. Biol. and Med. 39: 12-13, 1938. CrossrefGoogle Scholar10. HarrisMurrayPaineFinland HWRTFM: Streptomycin treatment of urinary tract infections, with special reference to use of alkali, Am. J. Med. 2: 229-250, 1947. CrossrefMedlineGoogle Scholar11. Heilman FR: Streptomycin in the treatment of experimental infection with microorganisms of the Friedländer group (Klebsiella), Proc. Staff Meet., Mayo Clin. 20: 33, 1945. Google Scholar12. HerrellNichols WEDR: The clinical use of streptomycin: a study of 45 cases, Proc. Staff Meet., Mayo Clin. 20: 449, 1945. MedlineGoogle Scholar13. HobbyMeyerChaffee GLKE: Activity of penicillin in vitro, Proc. Soc. Exper. Biol. and Med. 50: 277, 1942. CrossrefGoogle Scholar14. Keefer CS: Official statement concerning streptomycin, J. A. M. A. 131: 31, 1946. MedlineGoogle Scholar15. King SJ: Friedländer's bacillus meningitis with report of case treated unsuccessfully with sulfadiazine, Ann. Int. Med. 24: 272, 1946. LinkGoogle Scholar16. KleinmanShearerSprinz AMTPH: Streptomycin in urinary tract infections, J. Urol. 57: 599-610, 1947. CrossrefMedlineGoogle Scholar17. Miller RF: Personal communication. Google Scholar18. MontesReal GGWA: Meningitis purulenta a neumobacilo de Friedländer (Klebsiella pneumoniae) curado con dagenan, Bol. Soc. cubana de pediat. 12: 5, 1940. Google Scholar19. NelsonLong RAPH: The clinical use of sulfadiazine in the therapy of bacterial infections other than pneumonia, Bull. Johns Hopkins Hosp. 69: 303, 1941. Google Scholar20. NesbitBohne RMAW: A present day rationale for the treatment of urinary tuberculosis, J. A. M. A. 138: 937, 1948. CrossrefMedlineGoogle Scholar21. Raines SL: The present status of streptomycin therapy, J. Urol. 57: 79-83, 1947. CrossrefMedlineGoogle Scholar22. Robertson CW: Meningitis due to B. Friedländer: recovery of a case treated with sulfapyridine, Canad. M. A. J. 14: 70, 1941. Google Scholar23. SchlossDavidsonHilton EMJHKC: Klebsiella meningitis: a case cured with streptomycin, Ann. Int. Med. 29: 540-544, 1948. LinkGoogle Scholar24. SpenceBaird HMSS: Vesical diverticula: a clinical study with special reference to treatment, J. Urol. 58: 327-342, 1947. CrossrefMedlineGoogle Scholar25. SwartzRohds EPPA: Klebsiella (Friedländer's bacillus) infections in an army hospital, Am. J. Clin. Path. 16: 88, 1946. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Philadelphia, Pennsylvania*Received for publication July 2, 1949.From the Department of Medicine, service of Frieda Baumann, M.D., Philadelphia General Hospital, Philadelphia, Pennsylvania.†Present address: Guthrie Clinic, Sayre, Pa. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPyelonephritis und chronische interstitielle Nephritis 1 November 1951Volume 35, Issue 5Page: 1117-1124KeywordsBacillusHospital medicineKlebsiella pneumoniaePyelonephritisStreptomycinUrinary tract infections ePublished: 1 December 2008 Issue Published: 1 November 1951 PDF downloadLoading ...