A STUDY OF SYPHILIS OF THE AORTA AND AORTIC VALVE AREA
Authors: Charles F. Nichols
Journal: Annals of Internal Medicine (1940)

Article1 December 1940A STUDY OF SYPHILIS OF THE AORTA AND AORTIC VALVE AREACHARLES F. NICHOLS, M.D., F.A.C.P.CHARLES F. NICHOLS, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-14-6-960 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe widespread interest now manifested in the early diagnosis and adequate treatment of syphilis would seem to justify once again a review of the tragic effects of this disease on the cardiovascular system. The term "cardiovascular syphilis" is widely used but, in order properly to understand the evolution of the disease, the term "vascular syphilis" would be preferable. Excepting only cerebral vascular syphilis and rare involvement of other vessels (as the innominate artery), vascular syphilis in the great majority of cases resolves itself into syphilis of the aorta. Primary involvement of the aortic valves and heart, although it does occur,...References1. GAGER LT: quoted from, Syphilitic heart disease, Am. Jr. Syph., 1929, xiii, 411-418. Google Scholar2. PAULLIN JE: Cardiovascular syphilis, Jr. Am. Med. Assoc., 1937, cix, 1123-1125. CrossrefGoogle Scholar3. SCOTT RW: Diseases of the aorta, Oxford Med., 1927, ii, part 2, 508, 1-29. Google Scholar4. STOKESINGRAHAM JHNR: Dermatology and syphilology, public health problems: methods and policy in the control of syphilis, Am. Jr. Med. Sci., 1937, cxciv, 578-596. CrossrefGoogle Scholar5. MOOREDANGLADEREISINGER JEJHJC: Treatment of cardiovascular syphilis, results obtained in fifty-three patients with aortic aneurysm and in one hundred and twelve with aortic regurgitation, Arch. Int. Med., 1932, xlix, 879-924. CrossrefGoogle Scholar6. WILSON R: Studies in syphilitic cardiovascular disease. 1. Uncomplicated syphilitic aortitis: an asymptomatic condition, Am. Jr. Med. Sci., 1937, cxciv, 178-185. CrossrefGoogle Scholar7. MAYNARDCURRANROSENWILLIAMSONLINGG EPJAITCGC: Cardiovascular syphilis, early diagnosis and clinical course of aortitis in three hundred and forty-six cases of syphilis, Arch. Int. Med., 1935, lv, 873-894. CrossrefGoogle Scholar8. STEEL D: Roentgenological diagnosis of syphilitic. aortitis; review of forty proved cases, Am. Heart Jr., 1930, vi, 59-66. CrossrefGoogle Scholar9. SPROULL J: Status and clinical application of roentgenology of thoracic aorta, Am. Jr. Roentgenol., 1932, xxviii, 37-48. Google Scholar10. STOKESCOLEMOORE HHHNJE: Standard treatment procedure in early syphilis, Jr. Am. Med. Assoc., 1934, cii, 1267-1272. CrossrefGoogle Scholar11. OSTRUMROBINSONNICHOLS HBCF: Aneurysms of the aortic sinuses or sinuses of Valsalva, Am. Jr. Roentgenol., 1938 xl, 828-837. Google Scholar12. PAULLIN JE: Syphilis in the negro, Trans. Assoc. Am. Phys., 1927, xlii, 46-57. Google Scholar13. LONGCOPE WT: Syphilitic aortitis: its diagnosis and treatment, Arch. Int. Med., 1913, xi, 15-51. CrossrefGoogle Scholar14. KURTZEYSTER CMJA: Fluoroscopic studies of the heart and aorta in acquired and congenital syphilis, Am. Heart Jr., 1930, vi, 67-76. CrossrefGoogle Scholar15. HAMPTONBLANDSPRAGUE AOEFHB: Further studies of the aorta with special reference to luetic aortitis, Am. Heart Jr., 1930, vi, 77-81. CrossrefGoogle Scholar16. LEDBETTERHOLMESWHITE PVGWPD: Value of x-ray in determining cause of aortic regurgitation, Am. Heart Jr., 1925, i, 196-212. CrossrefGoogle Scholar17. GROSSSPARK HC: Coronary and extracoronary factors in hypertensive heart failure, Am. Heart Jr., 1938, xiv, 160-182. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Philadelphia, Pennsylvania*Received for publication August 10, 1938.From the Medical Service of Dr. Thomas F. Klein, The Philadelphia General Hospital. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byIdentifying Cardiovascular Syphilis at OperationMusical murmurs: Clinical implications, long-term prognosis, and echo-phonocardiographic featuresThe Interaction between Hyperlipidaemia and other Risk Factors in the Pathogenesis of Atherosclerosis (Lecture II)Pathogenetic mechanisms in atherosclerosisErkrankungen der thorakalen Aorta (außer Fehlbildungen)The racial incidence of heart disease at Groote Schuur Hospital, Cape Town. Part II. Hypertension and valvular disease of the heartUnusual musical murmurs of anterior cusp aortic regurgitationThe Balthazar-Foster Murmur and Foster's RuleSYPHILITIC HEART DISEASE IN THE AGED*FREDERIC D. ZEMAN, M.D., F.A.C.P., SIDNEY STORCH, M.D.Cardiovascular Syphilis 1 December 1940Volume 14, Issue 6Page: 960-977KeywordsAortaAortic valveArteriesCardiovascular diseasesHeartMedical servicesSyphilisVascular diseases ePublished: 1 December 2008 Issue Published: 1 December 1940 PDF downloadLoading ...