A LONG-TERM EVALUATION OF AUREOMYCIN IN THE TREATMENT OF ACTINOMYCOSIS
Authors: L V MCVAY, D H SPRUNT
Journal: Annals of Internal Medicine (1953)

Article1 May 1953A LONG-TERM EVALUATION OF AUREOMYCIN IN THE TREATMENT OF ACTINOMYCOSISLEON V. MCVAY JR., M.D., DOUGLAS H. SPRUNT, M.D., F.A.C.P.LEON V. MCVAY JR., M.D.Search for more papers by this author, DOUGLAS H. SPRUNT, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-38-5-955 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptWith the conquest of one infectious disease entity after another, attention has tended to concentrate on those conditions which have remained resistant to modern methods of therapy. Paramount among these diseases are those caused by the pathogenic fungi. No sphere in clinical research is more active than that concerned with the development of effective modes of treatment for such serious conditions as disseminated histoplasmosis, generalized coccidioidomycosis, cryptococcic meningitis, systemic North American blastomycosis and generalized actinomycosis.As interest in mycotic infections has grown they are being recognized more frequently. An excellent example is the increased number of cases of systemic North...Bibliography1. FriedmanSignorelli LLJJ: Blastomycosis: a review of the literature and a report of a case involving the meninges, Ann. Int. Med. 24: 385-400 (March) 1946. LinkGoogle Scholar2. LittmanWickerWarren MLEHAS: Systemic North American blastomycosis. Report of a case with cultural studies of the etiologic agent and observations on the effect of streptomycin and penicillin in vitro, Am. J. Path. 24: 339-365 (March) 1948. MedlineGoogle Scholar3. Smith DT: Immunologic types of blastomycosis: a report of 40 cases, Ann. Int. Med. 31: 463-469, 1949. LinkGoogle Scholar4. Benham RW: Cryptococcosis and blastomycosis, Ann. New York Acad. Sc. 50: 1299, 1950. CrossrefMedlineGoogle Scholar5. SchoenbachMillerGinsbergLong EBJMMPH: Systemic blastomycosis treated with stilbamidine, J. A. M. A. 146: 1317-1318 (Aug. 4) 1951. CrossrefMedlineGoogle Scholar6. NoojinPraytor ROHB: Systemic blastomycosis complicated with pregnancy, J. A. M. A. 147: 749-751 (Oct. 20) 1951. CrossrefMedlineGoogle Scholar7. SchwartzBaum JGL: Blastomycosis, Am. J. Clin. Path. 21: 999-1100 (Nov.) 1951. CrossrefMedlineGoogle Scholar8. McVayCarroll LVDS: Aureomycin in the treatment of systemic North American blastomycosis, Am. J. Med. 12: 289-301 (March) 1952. CrossrefMedlineGoogle Scholar9. SchoenbachMillerLong EBJMPH: Treatment of systemic blastomycosis with stilbamidine, Ann. Int. Med. 37: 31-47 (July) 1952. LinkGoogle Scholar10. SnapperSchneidMcVayLieben IBLF: Pharmacology and therapeutic value of diamidine derivatives—particularly of 2-hydroxystilbamidine, Tr. New York Acad. Sc. 14: 269-271 (May) 1952. CrossrefMedlineGoogle Scholar11. Martin DS: Fungous diseases involving the internal organs, in Harrison, T. R.: Principles of internal medicine, 1951, Blakiston and Co., Philadelphia, pp. 941-955. Google Scholar12. Israel J: Neue Beobachtungen auf dem Gebiete der Mykosen des Menschen, Arch. f. path. Anat. 74: 15-53, 1878. CrossrefGoogle Scholar13. WolffIsrael MJ: Über Reinculture des Actinomyces und seine Übertragbarkeit auf Thiere, Arch. f. path. Anat. 126: 11-59, 1891. CrossrefGoogle Scholar14. Wright JH: Biology of micro-organisms of actinomycosis, J. M. Research 13: 349-404, 1905. MedlineGoogle Scholar15. Davis MI: Analysis of forty-six cases of actinomycosis with special reference to its etiology, Am. J. Surg. 52: 447-454, 1941. CrossrefGoogle Scholar16. Cope Z: Actinomycosis, 1938, Oxford University Press, London. Google Scholar17. KolouchPeltier FLF: Recent advances in surgery: actinomycosis, Surgery 20: 401-430, 1946. MedlineGoogle Scholar18. Wangensteen OH: The role of surgery in the treatment of actinomycosis, Ann. Surg. 104: 752-770, 1936. CrossrefMedlineGoogle Scholar19. Poulton EP: Discussion of the treatment of bacterial diseases with substances related to sulphanilamide, Proc. Roy. Soc. Med. 31: 149-166, 1938. Google Scholar20. FloreyFlorey MEHW: General and local administration of penicillin, Lancet 1: 387-396, 1943. CrossrefGoogle Scholar21. DobsonCutting LWC: Penicillin and sulfonamides in the therapy of actinomycosis: report of 16 additional cases and in vitro tests of susceptibility of actinomyces to penicillin and sulfadiazine, J. A. M. A. 128: 856-863, 1945. CrossrefGoogle Scholar22. WalkerHamilton JMJW: Treatment of actinomycosis with penicillin, Ann. Surg. 121: 373-384, 1945. CrossrefMedlineGoogle Scholar23. HendricksonLehman GGEP: Cervicofacial actinomycosis successfully treated by penicillin without surgical drainage, J. A. M. A. 128: 438, 1945. CrossrefGoogle Scholar24. Kay EB: Pulmonary actinomycosis: its treatment by pulmonary resection in conjunction with chemotherapy: report of two cases, Ann. Surg. 124: 535-543, 1946. CrossrefGoogle Scholar25. RobertsTubbsBates JEOSM: Pleural and pulmonary suppuration treated with penicillin, Lancet 1: 39-45, 1945. CrossrefGoogle Scholar26. NicholsHerrell DRWE: Penicillin in treatment of actinomycosis, J. Lab. and Clin. Med. 32: 1405, 1947. Google Scholar27. SanfordBarnes GERO: Massive penicillin therapy of abdominal actinomycosis, Surgery 25: 711-723, 1949. MedlineGoogle Scholar28. McVayGuthrieSprunt LVFDH: Aureomycin in the treatment of actinomycosis, New England J. Med. 245: 91-96 (July 19) 1951. CrossrefMedlineGoogle Scholar29. McVayDunavantGuthrieSprunt LVDFDH: Treatment of actinomycosis with aureomycin, J. A. M. A. 143: 1067-1068 (July 22) 1950. CrossrefMedlineGoogle Scholar30. McVaySprunt LVDH: Streptokinase and streptodornase in the treatment of diabetic gangrene, Arch. Int. Med. 87: 551-559 (April) 1951. CrossrefGoogle Scholar31. Berg JA: Personal communication, Dutch M. J. (Nov. 8) 1952. Google Scholar32. MillerLongSchoenbach JMPHEB: Successful treatment of actinomycosis with stilbamidine, J. A. M. A. 150: 35 (Sept. 6) 1952. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Memphis, Tennessee*Received for publication December 27, 1952.From the Departments of Medicine, Pathology and Bacteriology, University of Tennessee College of Medicine, and the John Gaston Hospital, Memphis, Tennessee. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe Present Status of the Chemotherapeutic DrugsCase report primary actinomycosis of external oblique muscleAntimicrobial in Vitro Susceptibility of Actinomyces Israelii and Arachnia PropionicaPrimary Actinomycosis of the Abdominal WallSusceptibility of Pathogenic Actinomycetes to Antimicrobial CompoundsSystemic Mycoses—Primary Pathogenic FungiActinomycosisActinomycosisActinomycosisAktinomykoseAktinomykoseAntimicrobial therapy in patients sensitive to penicillinAnaerobic infectionsAbdominal actinomycosis: Changed concepts?Actinomycosis of the colonDas MycetomDie AktinomykoseDie AntimykoticaActinomycosis and nocardiosisACTINOMYCOSIS: ITS RECOGNITION AND TREATMENT*JOHN COLLINS HARVEY, M.D., JAMES R. CANTRELL, M.D., A. MURRAY FISHER, M.D.Actinomycosis and nocardiosisCervicofacial Actinomycosis: Report of a CaseActinomycosis: Some Concepts of Therapy and PrognosisChemistry of antibiotics of clinical importance 1 May 1953Volume 38, Issue 5Page: 955-966KeywordsActinomycosisAttentionBacteriologyBlastomycosisCoccidioidomycosisFungal pathogensHistoplasmosisHospital medicineInfectious diseasesMeningitis ePublished: 1 December 2008 Issue Published: 1 May 1953 PDF downloadLoading ...