Ecology of a Newly Recognized Common Respiratory Agent RS-Virus
Authors: VERNON KNIGHT
Journal: Annals of Internal Medicine (1961)

Clinical Staff Conference1 September 1961Ecology of a Newly Recognized Common Respiratory Agent RS-VirusCombined Clinical Staff Conference at theNational Institutes of HealthVERNON KNIGHT, M.D., F.A.C.P., ALBERT Z. KAPIKIAN, M.D., HOWARD M. KRAVETZ, M.D., ROBERT M. CHANOCK, M.D., J. A. MORRIS, PH.D., ROBERT J. HUEBNER, M.D., JOSEPH E. SMADEL, M.D., HUGH E. EVANS, M.D.VERNON KNIGHT, M.D., F.A.C.P.Search for more papers by this author, ALBERT Z. KAPIKIAN, M.D.Search for more papers by this author, HOWARD M. KRAVETZ, M.D.Search for more papers by this author, ROBERT M. CHANOCK, M.D.Search for more papers by this author, J. A. MORRIS, PH.D.Search for more papers by this author, ROBERT J. HUEBNER, M.D.Search for more papers by this author, JOSEPH E. SMADEL, M.D.Search for more papers by this author, HUGH E. EVANS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-55-3-507 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptDr. Vernon Knight: Participants in our program today will describe current research on the common cold and one agent, the respiratory syncytial virus, in particular. Volunteers for exposure to this virus came from Federal prisons in the area, and much of the credit for the success of the project to date goes to Mr. James Bennett, Director of Federal Prisons, and to Dr. Harold Janney, chief physician for the prison system, who have given us excellent cooperation.Studies with volunteers are not new and usually they are conducted within penal institutions. But it seemed to us that more precise, useful...References1. KAPIKIANBELLMASTROTAJOHNSONHUEBNERCHANOCK AZJAFMKMRJRM: An outbreak of febrile illness and pneumonia associated with respiratory syncytial infection. Amer. J. Hyg. 75: 1961 (Nov.) In press. Google Scholar2. KRAVETZKNIGHTCHANOCKMORRISJOHNSONRIFKINDUTZ HMVRMJAKMDJP: Respiratory syncytial virus. III. Production of illness and clinical observations in adult volunteers. J. A. M. A. 176: 657, 1961. MedlineGoogle Scholar3. MAERZPAUL AMR: A Dictionary of Color, 2nd Ed., McGraw-Hill Book Co., Inc., New York, 1950, plate 4, line 4. Google Scholar4. SWEETHILLEMAN BHMR: The vacuolating virus, S.V.40. Proc. Soc. Exp. Biol. Med. 105: 420, 1960. CrossrefMedlineGoogle Scholar5. SWEETHILLEMAN BHMR: Detection of a "non-detectable" simian virus (vacuolating virus) present in rhesus and cynomologus monkey kidney cell culture material. A preliminary report. Second Internat. Conf. on Live Poliovirus Vaccines, Pan. Am. Hlth. Org. and Wld. Hlth. Org., Washington, D. C., 1960, p. 79. Google Scholar6. SABIN AB: Personal communication. Google Scholar7. MORRISBLOUNTSAVAGE JARERE: Recovery of cytopathogenic agent from chimpanzees with coryza. Proc. Soc. Exp. Biol. Med. 92: 544, 1956. CrossrefMedlineGoogle Scholar8. CHANOCKROIZMANMYERS RMBR: Recovery from infants with respiratory illness of a virus related to chimpanzee coryza agent (CCA). I. Isolation, properties and characterization. Amer. J. Hyg. 66: 281, 1957. MedlineGoogle Scholar9. CHANOCKFINBERG RML: Recovery from infants with respiratory illness of a virus related to chimpanzee coryza agent (CCA). II. Epidemiologic aspects of infection in infants and young children. Amer. J. Hyg. 66: 291, 1957. MedlineGoogle Scholar10. CHANOCKKIMVARCOSKODELEVAJOHNSONCUMMINGPARROTT RMHWAJAKMCRH: Role of respiratory syncytial virus in bronchiolitis, pneumonia, and minor respiratory disease. I. Virus recovery and other observations during 1960 outbreak. J. A. M. A. 176: 647, 1961. CrossrefMedlineGoogle Scholar11. PARROTTVARGOSKOKIMCUMMINGTURNERHUEBNERCHANOCK RHAJHWCHCRJRM: Role of respiratory syncytial virus in bronchiolitis, pneumonia and pharyngitis with bronchitis in children. II. Serologic studies over a 34 month period. J. A. M. A. 176: 653, 1961. MedlineGoogle Scholar12. KAPIKIANJOHNSONCHANOCKDYKEEILERBELLHUEBNER AZKMRMLMREJARJ: A study of acute respiratory illness and virus infection on a college campus. To be published. Google Scholar13. JOHNSONCHANOCKRIFKINDKRAVETZKNIGHT KMRMDHMV: Respiratory syncytial virus. IV. Virus shedding, serologic response and illness. J. A. M. A. 176: 663, 1961. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Bethesda, MarylandReceived for publication May 31, 1961.This is an edited transcript of a combined clinical staff conference at the Clinical Center, Bethesda, Maryland, by the National Institute of Allergy and Infectious Diseases, National Institutes of Health, U. S. Public Health Service, Department of Health, Education, and Welfare.Requests for reprints should be addressed to Vernon Knight, M.D., Clinical Director, National Institute of Allergy and Infectious Diseases, Bethesda 14, Md. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byCommon Respiratory Viruses and Pulmonary Mucosal ImmunologyRespiratorische VirenThe Role of Immunity in the common Cold and Related Viral Respiratory Infections 1 September 1961Volume 55, Issue 3Page: 507-525KeywordsBronchiolitisCommon coldEcologyInfantsInfectious diseasesMedical servicesPneumoniaPoliomyelitisPrevention, policy, and public healthRespiratory syncytial virus ePublished: 1 December 2008 Issue Published: 1 September 1961 PDF downloadLoading ...