IDENTIFICATION OF URATE CRYSTALS IN GOUTY SYNOVIAL FLUID
Authors: D J MCCARTY, J L HOLLANDER
Journal: Annals of Internal Medicine (1961)

Article1 March 1961IDENTIFICATION OF URATE CRYSTALS IN GOUTY SYNOVIAL FLUIDDANIEL J. MCCARTY, M.D., JOSEPH L. HOLLANDER, M.D., F.A.C.P.DANIEL J. MCCARTY, M.D., JOSEPH L. HOLLANDER, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-54-3-452 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptUrate crystals have been noted in synovial fluid from gouty patients in the past, but this finding was believed to be infrequent and of little assistance to the clinician in his attempt to establish a diagnosis.1Recently one of us2reported that eight of 17 fluids from the affected joints of patients with clinical gout contained crystals seen by ordinary light microscopy, and in several of these cases the diagnosis of gout was first established on the basis of this finding.2It was noted that urate crystals in joint fluid were often short and rod-shaped, with rounded ends and parallel...Bibliography1. BauerCalkins WE, in Diseases of metabolism, edited by G. G. Duncan, p. 659. W. B. Saunders Co., Philadelphia, Pa., 1959. Google Scholar2. Hollander JL: Arthritis and allied conditions, 6th Ed., p. 77. Lea & Febiger, Philadelphia, Pa., 1960. Google Scholar3. Ro K: Biochem., Japan 14: 361, 1931. CrossrefGoogle Scholar4. RopesBauer MWW: Synovial fluid changes in joint disease, p. 92. Harvard University Press, Cambridge, Mass., 1953. Google Scholar5. Talbott JM: Gout, p. 40. Grune & Stratton, New York, 1957. Google Scholar6. Kling DM: The synovial membrane and the synovial fluid (with special reference to arthritis and injuries of the joints). Medical Press, Los Angeles, Calif., 1938. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Philadelphia, Pa.*Received for publication August 15, 1960.From the Arthritis Section, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pa.†Trainee, National Institute of Arthritis and Metabolic Diseases, USPHS.‡Chief, Arthritis Section, Department of Medicine, University of Pennsylvania School of Medicine.Requests for reprints should be addressed to Daniel J. McCarty, M.D., Department of Medicine, Hahnemann Medical College and Hospital, 230 N. Broad Street, Philadelphia 2, Pa. 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WEINBERGER, M.D., F.A.C.P.The pendulum of progress in gout: From crystals to hyperuricemia and backRecurrent acute (?gouty) arthritis in chronic renal failure treated with periodic hemodialysisCholesterol Crystals in Synovial FluidJACK ZUCKNER, M.D., JAMAL UDDIN, M.D., GEORGE E. GANTNER JR., M.D., ROBERT W. DORNER, PH.D.ACUTE GOUT—UNSOLVEDGout and Hyperuricemia after Adrenalectomy for HypertensionBiochemistry of Uric Acid and Its Relation to GoutDiagnosis of Gouty ArthritisThe old and new concepts of acute gouty arthritisDiarthrodial joints, an essayACUTE ARTHRITIS IN MAN AND DOG AFTER INTRASYNOVIAL INJECTION OF SODIUM URATE CRYSTALSThe Significance of Calcium Phosphate Crystals in the Synovial Fluid of Arthritic Patients: The "Pseudogout Syndrome" I. Clinical AspectsDANIEL J. MCCARTY JR., M.D., NORMAN N. KOHN, M.D., JAMES S. FAIRES, M.D.The Significance of Calcium Phosphate Crystals in the Synovial Fluid of Arthritic Patients: The "Pseudogout Syndrome" II. Identification of CrystalsNORMAN N. KOHN, M.D., ROBERT E. HUGHES, PH.D., DANIEL J. MCCARTY JR., M.D., JAMES S. FAIRES, M.D.The Present-Day Treatment of Gout 1 March 1961Volume 54, Issue 3Page: 452-460KeywordsArthritisAttentionGoutHospital medicineLight microscopyMetabolic disordersSynovial fluidUric acid ePublished: 1 December 2008 Issue Published: 1 March 1961 PDF downloadLoading ...