PNEUMOCOCCIC MENINGITIS SUCCESSFULLY TREATED WITH PENICILLIN AND SULFADIAZINE
Authors: James S. Sweeney, John T. Leslie
Journal: Annals of Internal Medicine (1946)

Case Reports1 April 1946PNEUMOCOCCIC MENINGITIS SUCCESSFULLY TREATED WITH PENICILLIN AND SULFADIAZINEJAMES S. SWEENEY, JOHN T. LESLIEJAMES S. SWEENEYSearch for more papers by this author, JOHN T. LESLIESearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-24-4-705 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe prognosis in cases of pneumococcic meningitis has improved considerably since the advent of the sulfonamides and still more so since penicillin.1, 2, 3, 4, 5, 6, 7, 8 The mortality rate, however, continues to be quite high. Very few individual cases or series of cases treated with penicillin or penicillin and sulfa drugs have been reported. It is anticipated that as more cases are reported and thus more experience gained, further improvement in methods of treatment will follow and in turn a material reduction will result in both mortality and morbidity.CASE REPORTA 22 year old white soldier...Bibliography1. SWEETDUMOFF-STANLEYDOWLINGLEPPER LKEHFMH: The treatment of pneumococcic meningitis with penicillin, Jr. Am. Med. Assoc., 1945, cclxiii, 263-267. CrossrefGoogle Scholar2. LITVOKAPPELBAUMGREENE AMEM: Pneumococcic meningitis, Am. Jr. Dis. Child., 1944, lxvii, 485-486. CrossrefGoogle Scholar3. HARFORDMARTINHAGEMANWOOD CGSPPOWB: Treatment of staphylococcic, pneumococcic, gonococcic and other infections with penicillin, Jr. Am. Med. Assoc., 1945, cxxvii, 325-329. CrossrefGoogle Scholar4. DAWSONHOBBY MHGL: The clinical use of penicillin, Jr. Am. Med. Assoc., 1944, cxxiv, 611-622. CrossrefGoogle Scholar5. EVANS AL: The treatment of intracranial infections with penicillin, Jr. Am. Med. Assoc., 1944, cxxiv, 641-643. CrossrefGoogle Scholar6. WARINGSMITH AJMH: Combined penicillin and sulfonamide therapy in the treatment of pneumococcic meningitis, Jr. Am. Med. Assoc., 1944, cxxvi, 418-424. CrossrefGoogle Scholar7. ROSENBERGARLING DHPA: Penicillin in the treatment of meningitis, Jr. Am. Med. Assoc., 1944, cxxv, 1011-1017. CrossrefGoogle Scholar8. CAIRNSDUTHIELEWINSMITH HESWSHV: Pneumococcal meningitis treated with penicillin, Lancet, 1944, i, 655. CrossrefGoogle Scholar9. RUEGSEGGER JM: Pneumococcal meningitis, Ann. Int. Med., 1942, xvii, 693-721. Google Scholar10. JOHNSONWALKER HCEA: Intraventricular penicillin, Jr. Am. Med. Assoc., 1945, cxxvii, 217-219. CrossrefGoogle Scholar11. COOKEGOLDRING JVD: The concentration of penicillin in various body fluids during penicillin therapy, Jr. Am. Med. Assoc., 1945, cxxvii, 80-87. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: JAMES S. SWEENEY; JOHN T. LESLIE*Received for publication April 9, 1945.From Bushnell General Hospital. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDie Infektionskrankheiten 1 April 1946Volume 24, Issue 4 Page: 705-707 Keywords Death rates Drugs Meningitis Morbidity Mortality Penicillin Sulfonamide ePublished: 1 December 2008 Issue Published: 1 April 1946 PDF downloadLoading ...