THE EFFECT OF X-RAY THERAPY ON GASTRIC ACIDITY AND ON 17-HYDROXYCORTICOID AND UROPEPSIN EXCRETION
Authors: J A RIDER, H C MOELLER, T L ALTHAUSEN, G E SHELINE
Journal: Annals of Internal Medicine (1957)

Article1 October 1957THE EFFECT OF X-RAY THERAPY ON GASTRIC ACIDITY AND ON 17-HYDROXYCORTICOID AND UROPEPSIN EXCRETIONJ. A. RIDER, M.D., H. C. MOELLER, M.D., T. L. ALTHAUSEN, M.D., F.A.C.P., G. E. SHELINE, M.D.J. A. RIDER, M.D.Search for more papers by this author, H. C. MOELLER, M.D.Search for more papers by this author, T. L. ALTHAUSEN, M.D., F.A.C.P.Search for more papers by this author, G. E. SHELINE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-47-4-651 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptFree gastric hydrochloric acid is essential for the production of peptic ulcer. It is possible by x-radiation to decrease or even abolish production of this acid, leading to subsequent healing of the ulcer. These observations serve as the rationale for the clinical use of x-ray therapy in the management of peptic ulcer.Since Regaud et al.1first studied the effect of x-ray on gastric secretion, numerous reports have indicated not only that irradiation will decrease gastric secretion, but also that, in general, the greater the exposure, the greater the decrease. In 1917 Bruegel2reported the use of external x-ray radiation...Bibliography1. RegaudNogierLacassagne CTA: Sur les effets redoutables des irradiations étendues de l'abdomen et sur les lésions du tube digestif déterminées par les rayons de Röntgen, Arch. d'electr. med. 21: 321-334, 1912. Google Scholar2. Bruegel C: Die Beinflussung des Magenchemismus durch Röntgenstrahlen, München. med. Wchnschr. 64: 379-380, 1917. Google Scholar3. Simon N: Suppression of gastric acidity with beta particles of P32 , Science 109: 563-564, 1949. CrossrefMedlineGoogle Scholar4. 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Author, Article, and Disclosure InformationAffiliations: San Francisco, California*From the Symposium on Gastroduodenal Ulcer, presented at the Thirty-eighth Annual Session of The American College of Physicians, Boston, Massachusetts, April 11, 1957.From the Gastrointestinal Clinic, Department of Medicine, and the Department of Radiology, University of California School of Medicine, San Francisco.Requests for reprints should be addressed to J. Alfred Rider, M.D., University of California Medical Center, San Francisco 22, California. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byRadiation GastritisRelative Radiosensitivities of the Small and Large IntestineAcute gastric mucosal injury during continuous or interrupted aspirin ingestion in humansFunktionelle StrahlentherapieGastric irradiation in the treatment of peptic ulcer patients who are poor surgical risksPHYSIOLOGICAL EFFECTS AND CLINICAL EVALUATION OF GLYCOPYRROLATE IN PEPTIC ULCER DISEASEPHYSIOLOGICAL EFFECTS AND CLINICAL EVALUATION OF GLYCOPYRROLATE IN PEPTIC ULCER DISEASEUlcerogenic drugs and technicsDiscussion on the Changes Produced in Tissues by IrradiationSuperficial Gastritis 1 October 1957Volume 47, Issue 4Page: 651-665KeywordsDiagnostic radiologyExcretionGastric ulcersHydrochloric acidPeptic ulcersUlcers ePublished: 1 December 2008 Issue Published: 1 October 1957 PDF downloadLoading ...