A CASE OF NITROBENZENE POISONING
Authors: Zolton T. Wirtschafter, Ralph Wolpaw
Journal: Annals of Internal Medicine (1944)

Case Reports1 July 1944A CASE OF NITROBENZENE POISONINGZOLTON T. WIRTSCHAFTER, M.D., RALPH WOLPAW, M.D.ZOLTON T. WIRTSCHAFTER, M.D.Search for more papers by this author, RALPH WOLPAW, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-21-1-135 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptNitrobenzene, or Oil of Mirbane as it is known commercially, is a common solvent for a number of every day substances such as shoe polishes and dyes, lacquers, indelible inks, cheap perfumes, and a variety of other things. It is toxic to man by ingestion, direct contact, or inhalation or a combination of any of these avenues. Sollmann15states that a dose of as little as one gram may be fatal. The symptoms and signs of poisoning are nausea, vomiting, prostration, intense gray blue cyanosis, convulsions, and coma (Sollmann). As with other benzene derivatives, there is a direct toxic effect...Bibliography1. BROOKS MM: Inhibition by glucose of methemoglobin formation, Proc. Soc. Exper. Biol. and Med., 1934, xxxii, 63-64. CrossrefGoogle Scholar2. CISSELL E: Vergiftung mit 100 grams Nitrobenzol; Heilung, Med.-chir. Centralbl., Wien, 1894, xxix, 171. Abstract, Lancet, 1894, i, 1521. Google Scholar3. CLARKPAUL BBWD: Acute methemoglobinemia following exposure to metadinitrobenzene, Jr. Iowa Med. Soc., 1935, xxv, 449-450. Google Scholar4. DODD AH: Poisoning by nitrobenzol: recovery, Brit. Med. Jr., 1891, i, 849-850. Google Scholar5. DRESBACHCHANDLER MWL: Some physiological disturbances induced in animals by nitrobenzol fumigation, Proc. Am. Physiol. Soc., Am. Jr. Physiol., 1917, xlii, 604-605. Google Scholar6. DRESBACHCHANDLER MWL: The toxic action of nitrobenzene, with special reference to the cerebellum, Proc. Soc. Exper. Biol. and Med., 1918, xv, 136. CrossrefGoogle Scholar7. ERSKINE D: Methaemoglobinemia in 4 sisters due to furniture polish (metadinitrobenzene) poisoning, Guy's Hosp. Rep., 1931, lxxxi, 418-420. Google Scholar8. FULLERTON WW: Two rather uncommon fatal cases of poisoning; nitrobenzene poisoning, suicidal; sodium fluoride, accidental, New England Jr. Med., 1930, cciii, 423. CrossrefGoogle Scholar9. MULLER F: Ueber Anilin-Vergiftung, Deutsch. med. Wchnschr., 1887, xiii, 27. CrossrefGoogle Scholar10. Personal communication from B. Heller and Company, Chicago, Ill. Google Scholar11. Personal communication from Dr. Milton Helpern, Assist. Med. Examiner, New York, N. Y. Google Scholar12. PRUETTBAUM WVEE: Nitrobenzol (oil of mirbane) poisoning, Jr. Oklahoma Med. Assoc., 1929, xxii, 134-135. Google Scholar13. SCOTTHANZLIK RWPJ: Poisoning by alcohol "denatured" with nitrobenzene, Jr. Am. Med. Assoc., 1920, lxxiv, 1000. CrossrefGoogle Scholar14. SMITH FJ: A case of aniline poisoning, Lancet, 1894, i, 89-90. CrossrefGoogle Scholar15. SOLLMANN T: A manual of pharmacology, 1936, W. B. Saunders Co., Philadelphia, pp. 623-624. Google Scholar16. SPINNER JR: Nitrobenzol not abortifacient, Cor.-Bl. f. Schweiz. Aerzte, Basel, 1917, xlvii, 1439. Abstract, Jr. Am. Med. Assoc., 1917, lxix, 2155. Google Scholar17. STIFEL RE: Methemoglobinemia due to poisoning by shoe dye, Jr. Am. Med. Assoc., 1919, lxxii, 395-396. CrossrefGoogle Scholar18. WALTERSKIRCHEN L: Ein Fall von Mirbanolvergiftung, Wien. klin. Wchnschr., 1939, lii, 317-318. Google Scholar19. WRIGHT-SMITH RJ: Poisoning by nitrobenzene or "essence of mirbane" with recovery, Med. Jr. Australia, 1929, i, 867-868. CrossrefGoogle Scholar20. ZUCCOLA P: Nitrobenzene poisoning, 1918, Policlinico, Rome. Abstract, Jr. Am. Med. Assoc., 1919, lxxii, 231. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication July 13, 1942.†Stark General Hospital, Charleston, S. C. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byToxicological Profile for Nitrobenzene 1 July 1944Volume 21, Issue 1Page: 135-141KeywordsComaConvulsionsIngestionInhalationNauseaOilsSigns and symptomsVomiting ePublished: 1 December 2008 Issue Published: 1 July 1944 PDF downloadLoading ...