CLINICAL EVALUATION OF CEDILANID
Authors: Maurice Sokolow, Francis L. Chamberlain
Journal: Annals of Internal Medicine (1943)

Article1 February 1943CLINICAL EVALUATION OF CEDILANIDMAURICE SOKOLOW, M.D., FRANCIS L. CHAMBERLAIN, M.D.MAURICE SOKOLOW, M.D.Search for more papers by this author, FRANCIS L. CHAMBERLAIN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-18-2-204 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe pure glycosides of digitalis have been the subject of many recent pharmacological and clinical investigations. Originally all the studies were purely chemical, but they have assumed clinical importance. The crude whole leaf ofDigitalis purpureacommonly used in clinical medicine has never been an ideal therapeutic agent. The various preparations differ widely in composition and potency, and require biological standardization. Furthermore, the U.S.P. product may vary in strength with each revision. For instance, the digitalis in U.S.P. XI is approximately 30 per cent more potent than that in U.S.P. X, and the United States Pharmacopeia allows a 40 per...Bibliography1. GOLD H: Digitalis in heart failure, New York State Jr. Med., 1941, xli, 496. Google Scholar2. SMITH S: II. Digitalis glucosides, Jr. Chem. Soc., 1930, 2478. SMITH, SYDNEY: III. Digitalis glucosides, Jr. Chem. Soc., 1931, 23. CrossrefGoogle Scholar3. STOLL A: The cardiac glycosides, 1937, Pharmaceutical Press, London. Google Scholar4. MOEVISSCHER GKMB: Studies on the native glucosides of digitalis lanata, Jr. Pharmacol. and Exper. Therap., 1938, lxiv, 65. Google Scholar5. WAYNE EJ: Clinical observations on two pure glucosides of digitalis, digoxin and digitalinum verum, Clin. Sci., 1933, i, 63. Google Scholar6. JUNETBIANCHI RM: Etude clinique d'un nouveau digitaligal, le digilande, Rev. méd. de la Suisse Rom., 1939, lix, 139. Google Scholar7. MICHAUD L: L'emptoi du digilanide C en clinique, Schweiz. med. Wchnschr., 1938, xix, 1338. Google Scholar8. GOLDKWITCATTELL HNTM: Studies on purified digitalis glucosides. I. Jr. Pharmacol. and Exper. Therap., 1940, lxix, 177. Google Scholar9. KWITGOLDCATTELL NTHM: Studies on purified digitalis glucosides. II. Jr. Pharmacol. and Exper. Therap., 1940, lxx, 254. Google Scholar10. CATTELLGOLD MH: Studies on purified digitalis glucosides, III. Jr. Pharmacol. and Exper. Therap., 1941, lxxi, 114. Google Scholar11. FAHRLADUE GJ: A preliminary investigation of the therapeutic value of lanatoside C (cedilanid), Am. Heart Jr., 1941, xxi, 133. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: San Francisco, California*Received for publication December 8, 1941.From the Department of Medicine, University of California Medical School, San Francisco.Aided by a grant from the Sandoz Chemical Works, Inc. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPrompt Myocardial Damage Contributes to Hepatic, Renal, and Intestinal Injuries Soon After a Severe Burn in RatsHerzinsuffizienzAnd More on DigitalisSummary of Current TherapyTherapie der HerzinsuffizienzQuantitatives zur Therapie mit HerzglykosidenVergleichende DigitalistherapieAtrial flutterThe Clinical Use of Digitalis PreparationsRecent Advances in Cardiovascular DiseaseCare of the Patient with Chronic Heart Disease 1 February 1943Volume 18, Issue 2Page: 204-213KeywordsGlycosidesUnited States pharmacopeia ePublished: 1 December 2008 Issue Published: 1 February 1943 PDF downloadLoading ...