POSTURAL ADJUSTMENTS AND PROTEIN EXCRETION BY THE KIDNEY IN RENAL DISEASE
Authors: S E KING
Journal: Annals of Internal Medicine (1957)

Article1 February 1957POSTURAL ADJUSTMENTS AND PROTEIN EXCRETION BY THE KIDNEY IN RENAL DISEASES. EDWARD KING, M.S., M.D., F.A.C.P.S. EDWARD KING, M.S., M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-46-2-360 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptINTRODUCTIONProtein excreted by the kidney is derived from the serum proteins filtered through the glomerulus.1 Considerable evidence2, 3 suggests that protein may be re-absorbed from the glomerular filtrate by the renal tubules. Divergence of opinion exists as to whether this tubular re-absorptive function is active normally, and as to its relative importance in renal disease. Protein may be excreted by the normal kidney during congestive heart failure1 following exposure to cold,4 after exercise,5 and under various conditions producing considerable alterations in the renal circulation, including ischemia from the effect of adrenal medullary amines.6Over the long term, protein excretion...Bibliography1. Smith H: The kidney: structure and function in health and disease, 1951, Oxford University Press, New York. Google Scholar2. Rather LJ: Filtration, resorption and excretion of protein by the kidney, Medicine 31: 357-380, 1952. CrossrefMedlineGoogle Scholar3. Squire JR: The nephrotic syndrome, Advances in Int. Med. 7: 201-241, 1955. MedlineGoogle Scholar4. ChesleyMarkowitzWetchler LGIB: Proteinuria following momentary vascular constriction, J. Clin. Investigation 18: 617-620, 1939. CrossrefMedlineGoogle Scholar5. WhiteRolf HLD: Effects of exercise and of some other influences on the renal circulation in man, Am. J. Physiol. 152: 505-516, 1948. 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Google Scholar19. King SE: Patterns of protein excretion by the kidneys, Ann. Int. Med. 42: 296-322, 1955. LinkGoogle Scholar20. King SE: Reliability of urine protein excretion patterns in chronic renal disease, Report, Research and Development, U. S. Army, in preparation. Google Scholar21. FosterRickWolfson PWJJWQ: Extension of standard biuret method to estimation of total protein in urine, J. Lab. and Clin. Med. 39: 618-623, 1952. MedlineGoogle Scholar22. GoldringChasis WH: Hypertension and hypertensive disease, 1944, The Commonwealth Fund, New York. Google Scholar23. SmithFinkelsteinAliminosaCrawfordGraber HWNLBM: The renal clearances of substituted hippuric acid derivatives and other aromatic acids in dog and man, J. Clin. Investigation 24: 388-404, 1937. CrossrefGoogle Scholar24. WalkerLev HMJ: Statistical inference, 1953, Henry Holt and Co., New York. CrossrefGoogle Scholar25. KingBaldwin SEDS: Unpublished observations. Google Scholar26. KingBaldwin SEDS: Renal hemodynamics during erect lordosis in normal man and subjects with orthostatic proteinuria, Proc. Soc. Exper. Biol. and Med. 86: 634-636, 1954. CrossrefMedlineGoogle Scholar27. WolfCardonShepard SPVHM: Life stress and essential hypertension, 1955, The Williams & Wilkins Co., Baltimore. Google Scholar28. Chinard FP: Transactions of the Third Conference on Renal Function, 1951, Josiah Macy, Jr. Foundation, New York. Google Scholar29. Sulkowitch H: The urinary excretion of the epinephrines in anxiety states, J. Clin. Investigation 35: 738, 1956. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Received for publication June 29, 1956.This work was performed at the Renal Research Laboratory, Governors Island, New York, N. Y.Requests for reprints should be addressed to S. Edward King, M.D., 30 East Fortieth Street, New York 16, N. Y. 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HERDMAN, M.D., ALFRED F. MICHAEL, M.D., ROBERT A. GOOD, M.D. 1 February 1957Volume 46, Issue 2Page: 360-377KeywordsAttentionExcretionNephritisProteinsProteinuriaRenal circulationRenal diseasesRenal ischemiaSerum proteinsVasoconstriction ePublished: 1 December 2008 Issue Published: 1 February 1957 PDF downloadLoading ...