MARKED LEUKOCYTOSIS RESULTING FROM CARCINOMATOSIS
Authors: W F HUGHES, C S HIGLEY
Journal: Annals of Internal Medicine (1952)

Case Reports1 November 1952MARKED LEUKOCYTOSIS RESULTING FROM CARCINOMATOSISWILLIAM F. HUGHES, M.D., CHARLES S. HIGLEY, M.D. F.A.C.P.WILLIAM F. HUGHES, M.D., CHARLES S. HIGLEY, M.D. F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-37-5-1085 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn any patient showing a marked leukocytosis, leukemia is usually suspected first. However, leukocytosis of unusual degree may result from severe infection, intoxications, rapid blood loss or malignancy. This case is presented to illustrate that carcinoma of the suprarenal gland with widespread metastasis showing necrosis may result in a marked stimulation to the production of white blood cells.CASE REPORTA 59 year old white female was admitted to St. Luke's Hospital on March 3, 1949. Her present illness had begun approximately eight weeks before admission with sudden onset of ease of fatigue, weakness and anorexia. The patient was confined...Bibliography1. KrackeParker RRFP: A textbook of clinical pathology, 1940, The Williams and Wilkins Co., Baltimore. Google Scholar2. Shoemaker AM: Carcinoma of spleen and stomach, with unusual blood picture, J. A. M. A. 55: 774, 1910. CrossrefGoogle Scholar3. Krumbhaar EB: Leukemoid blood pictures in various clinical conditions, Am. J. M. Sc. 172: 519, 1926. CrossrefGoogle Scholar4. OwensWalker MJMA: Carcinoma of the stomach with early leukocytosis, J. Kansas M. Soc. 35: 384, 1934. Google Scholar5. MeyerRotter LMSD: Leukemoid reaction (hyperleukocytosis) in malignancy, Am. J. Clin. Path. 12: 218, 1942. CrossrefGoogle Scholar6. HinshawHoxie DBHJ: Leukemoid reactions in carcinomas, California Med. 71: 300, 1949. MedlineGoogle Scholar7. Sotelo-Ortiz F: Leukemoid reaction occurring in carcinoma of ovary, Bull. Hosp. Joint Dis. 8: 86, 1947. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication August 3, 1951. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byGranulocyte colony-stimulating factor-producing gingival squamous cell carcinoma with epithelial-mesenchymal transition: Report of two casesParaneoplastic leukemoid reaction in a localised squamous cell oesophageal cancer with paracrine G-CSF productionGranulocyte colony-stimulating factor-producing squamous cell carcinoma of the tongue exhibiting characteristic fluorine-18 deoxyglucose accumulation on positron emission tomography–computed tomography: A case reportEsophageal adenocarcinoma with leukemoid reaction: a case reportSevere neutrophilic leukocytosis as a progression marker in granulocyte colony-stimulating factor-producing squamous cell carcinoma of the esophagusMultidisciplinary therapy for granulocyte‐colony‐stimulating factor producing carcinosarcoma of the esophagus: report of a caseG-CSF-producing esophageal cancer with induction of intense bone marrow FDG uptakeLeukemoid Reaction: A Rare Paraneoplastic Syndrome in Bladder Cancer Associated With a Grave PrognosisGranulocyte colony-stimulating factor-producing squamous cell carcinoma of the lower gingiva: a case reportCarcinosarcoma of the esophagus producing granulocyte-colony stimulating factor: report of a caseLeukemoid Reaction Resulting from Granulocyte Colony‐Stimulating Factor Producing Urothelial Carcinoma of the Renal PelvisGranulocyte-colony stimulating factor producing urothelial carcinoma of renal pelvisGingival cancer suspected of producing granulocyte colony-stimulating factor: Report of a caseA CASE OF GRANULOCYTE-COLONY STIMULATING FACTOR PRODUCING GALLBLADDER CANCERDetection of Epstein-Barr Virus DNA in Gastric Carcinoma with Lymphoid StromaProduction of granulocyte colony-stimulating factor by head and neck carcinomasGranulocyte Colony-Stimulating FactorGranulocyte colony-stimulating factor and its receptorGranulocyte Colony-Stimulating FactorHematologic manifestations of malignancyLeukocytosis due to adrenal metastases from malignant melanoma: Reversal after bilateral adrenalectomy with long-term survivalTumor-derived Growth Factors That Support Proliferation and Differentiation of Normal and Leukemic Hemopoietic CellsClear cell carcinoma of the ovary with colony-stimulating-factor production. Occurrence of marked granulocytosis in a patient and nude miceGranulocytosis and colony-stimulating activity (CSA) produced by a human squamous cell carcinomaAN AUTOPSY CASE OF LIPOSARCOMA WITH GRANULOCYTIC LEUKEMOID REACTIONLeukemoid Reaction, Thrombocytosis and Hypercalcemia Associated with Bladder Cancer 1 November 1952Volume 37, Issue 5Page: 1085-1088KeywordsBloodCarcinomatosisFatigueIntoxicationLeukocytosisNecrosisSevere blood lossWhite blood cells ePublished: 1 December 2008 Issue Published: 1 November 1952 PDF downloadLoading ...