NORMOCHOLESTEROLEMIC XANTHOMATOSIS: REPORT OF A CASE WITH MYOCARDIAL FIBROSIS AND MYELOSCLEROSIS
Authors: W H LYLE, B J LEONARD, W E BOWDEN, D G MILLER
Journal: Annals of Internal Medicine (1960)

Case Reports1 December 1960NORMOCHOLESTEROLEMIC XANTHOMATOSIS: REPORT OF A CASE WITH MYOCARDIAL FIBROSIS AND MYELOSCLEROSISW. H. LYLE, M.D., B. J. LEONARD, M.D., W. E. BOWDEN, M.B., Ch.B., D. G. MILLER, M.B., Ch.B.W. H. LYLE, M.D.Search for more papers by this author, B. J. LEONARD, M.D.Search for more papers by this author, W. E. BOWDEN, M.B., Ch.B.Search for more papers by this author, D. G. MILLER, M.B., Ch.B.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-53-6-1260 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe xanthomatoses are usually classified in two groups, one with normal, the other with raised levels of cholesterol in the blood. The first comprises Hand-Schüller-Christian disease, Letterer-Siwe disease, eosinophilic granuloma, and a number offormes frustesand mixtures of these. That these conditions, so diverse in their clinical presentation, are histologically similar is generally agreed.4Rowland8in 1928 showed that the foam cells which dermatologists had long known to be characteristic of the skin lesions of xanthoma disseminatum were also to be found in various tissues in Hand-Schüller-Christian disease, although the two conditions are rarely found in the same patient,...Bibliography1. CavanaghRussell JBDS: Xanthomatosis with diabetes insipidus in adults: a report of two cases, J. Path. and Bact. 68: 165, 1954. CrossrefMedlineGoogle Scholar2. Hansen PB: Relationship of Hand-Schüller-Christian's disease, Letterer-Siwe's disease and eosinophilic granuloma of bone (with report of 5 cases), Acta radiol. 32: 89, 1949. CrossrefMedlineGoogle Scholar3. LeonardIsraelsWilkinson BJMCJF: Myelosclerosis. A clinicopathological study, Quart. J. Med. 26: 131, 1957. MedlineGoogle Scholar4. Mallory TB: Medical progress. Pathology: diseases of bone, New England J. Med. 227: 955, 1942. CrossrefGoogle Scholar5. Mulcahy F: Bone changes in myelosclerosis, Proc. Roy. Soc. Med. 50: 100, 1957. CrossrefMedlineGoogle Scholar6. Nitter L: Three cases of eosinophilic granuloma in children, Acta radiol. 46: 731, 1956. CrossrefMedlineGoogle Scholar7. OswaldParkinson NT: Honeycomb lungs, Quart. J. Med. 18: 1, 1949. MedlineGoogle Scholar8. Rowland RS: Xanthomatosis and the reticulo-endothelial system: correlation of an unidentified group of cases described as defects in membranous bones, exophthalmos, and diabetes insipidus (Christian's syndrome), Arch. Int. Med. 42: 611, 1928. CrossrefGoogle Scholar9. Snapper I: Medical clinics on bone diseases, 1943, Interscience Publications, Inc., New York. Google Scholar10. Thannhauser SJ: Lipidoses, 1950, Oxford University Press, New York. Google Scholar11. ThompsonKeeganDunn CQJJAD: Defects of membranous bones, exophthalmos and diabetes insipidus. Report of a case, with necropsy, Arch. Int. Med. 36: 650, 1925. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication August 28, 1959.From the University of Manchester, Manchester, England.Requests for reprints should be addressed to W. H. Lyle, M.D., 371 Newton Road, Lowton, near Warrington, Lancashire, England. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byXanthoma disseminatum: A child with respiratory system involvement and bronchiectasisGENERALIZED NON-LANGERHANS CELL HISTIOCYTOSIS: FOUR CASES ILLUSTRATE A SPECTRUM OF DISEASEA suspicious lump in the neckXanthoma disseminatum: its otolaryngological manifestationsOsseous xanthomatosis and pathologic fractures in familial hyperlipemia (hyperglyceridemia) 1 December 1960Volume 53, Issue 6Page: 1260-1270KeywordsCholesterolElectrocardiographyFibrosisGranulomasHypertensionLesionsLipidsMetastasisMyocardial fibrosisThorax ePublished: 1 December 2008 Issue Published: 1 December 1960 PDF downloadLoading ...