HYPOVENTILATION SYNDROME: PHYSIOLOGIC STUDIES IN SELECTED CASES
Authors: E O COATES, G L BRINKMAN, F E NOE
Journal: Annals of Internal Medicine (1958)

Article1 January 1958HYPOVENTILATION SYNDROME: PHYSIOLOGIC STUDIES IN SELECTED CASESE. OSBORNE COATES JR., M.D., F.A.C.P., GEOFFREY L. BRINKMAN, M.D., FRANCES E. NOE, M.D.E. OSBORNE COATES JR., M.D., F.A.C.P., GEOFFREY L. BRINKMAN, M.D., FRANCES E. NOE, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-48-1-50 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptHypoventilation of the lungs, leading to lowered arterial oxygen saturation, carbon dioxide retention and respiratory acidosis, has long been recognized as a prominent feature of diffuse obstructive emphysema. Less well appreciated is the fact that significant hypoventilation may occur in other conditions both with and without obvious evidence of pulmonary disease. Prompt recognition of this situation is essential, since further reduction of ventilation, such as may result from the use of narcotics, or injudicious treatment with oxygen, may produce serious consequences. In addition, mental symptoms, presumably related to carbon dioxide retention, may develop in these individuals. These are particularly important...Bibliography1. Scholander PF: Analyzer for accurate estimation of respiratory gases in one-half cubic centimeter samples, J. Biol. Chem. 167: 235, 1947. CrossrefMedlineGoogle Scholar2. Van SlykeNeill DDJM: Determination of gases in blood and other solutions by vacuum extraction and manometric measurements, J. Biol. Chem. 61: 523, 1924. CrossrefGoogle Scholar3. BrinkmanJohnsDonosoRiley GLCJHRL: A modification of the method of Riley, Proemmel and Franke for determination of oxygen and carbon dioxide tensions in blood, J. Appl. Physiol. 7: 340 (Nov.) 1954. CrossrefMedlineGoogle Scholar4. 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PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe pathophysiology of obesity hypoventilation syndromeSchlafstörungen und Pickwick-SyndromObservations on some clinical features of extreme obesity, with particular reference to cardiorespiratory effects 1 January 1958Volume 48, Issue 1Page: 50-59KeywordsAttentionCarbon dioxideEmphysemaFibrosisLungsOxygenParalysisPulmonary diseasesRespirationThorax ePublished: 1 December 2008 Issue Published: 1 January 1958 PDF downloadLoading ...