CANCER DIAGNOSIS BY BONE MARROW SMEARS
Authors: C H JAIMET, H E AMY
Journal: Annals of Internal Medicine (1956)

Article1 April 1956CANCER DIAGNOSIS BY BONE MARROW SMEARSC. H. JAIMET, M.D., F.R.C.P.(C), F.A.C.P., H. E. AMY, B.A., R.T.C. H. JAIMET, M.D., F.R.C.P.(C), F.A.C.P.Search for more papers by this author, H. E. AMY, B.A., R.T.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-44-4-617 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe early diagnosis of cancer by examination of bone marrow smears is so often achieved that this test has become routine in our two hospitals. We have studied the marrow aspirates from over 4,100 patients to date and this forms the basis of our report.Three cases, of many such, can hardly fail to interest the diagnostician. An 80 year old man, in hospital for routine check-up, had diverticulosis coli without complications. His general health and all other tests, including x-rays and urologic study, were negative. A routine sternal marrow aspiration showed cancer cells, but clinical reëxamination failed to confirm...Bibliography1. AmyJaimet HECH: Tumour cells in the bone marrow smear, Canad. M. A. J. 69: 424-426, 1953. MedlineGoogle Scholar2. FademBerlin RSI: Comparisons between bone marrow differentials prepared from particles and from random samples of aspirate and determinations of dilutions of aspirate with peripheral blood utilizing radioactive phosphorus (P32), Blood 6: 160-173, 1951. CrossrefMedlineGoogle Scholar3. Berman L: Malignant lymphomas, their classification and relation to leukaemia, Blood 8: 195-210, 1953. CrossrefMedlineGoogle Scholar4. RohrHegglin KR: Tumorzellen im Sternalpunktat, Deutsches Arch. f. klin. Med. 179: 61, 1936. Google Scholar5. Amy HE: Pathological cytology in sternal marrow, Canad. J. M. Tech. 13: 57-63 (June) 1951. MedlineGoogle Scholar6. TischendorfFrank WA: Tumorzellen im Knochenmark, Lymphknoten und Organpunktat, Deutsches Arch. f. klin. Med. 186: 534, 1940. Google Scholar7. KreybergPoppe LE: Tumour cells in sternal bone marrow, Lancet 1: 593, 1940. CrossrefGoogle Scholar8. KleinBlock HM: Bone marrow plasmocytosis, Blood 8: 1034-41, 1953. CrossrefMedlineGoogle Scholar9. Fagraeus A: Antibody production in relation to the development of plasma cells, in vivo and in vitro experiments, Acta med. Scandinav. Suppl. 204, 1948. Google Scholar10. Moeschlin S: Phasenkontrastuntersuchungen in der Hämatologie, Acta haematol. 2: 399, 1949. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Hamilton, Ontario,*Received for publication October 28, 1955.†Clinical Director, Department of Medical Research, McMaster University; Staff of General Medicine and Haematology, Hamilton General Hospital and St. Joseph's Hospital, Hamilton.‡Department of Haematology, Hamilton General Hospital; Research Associate, Department of Medical Research, McMaster University. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byCalcium metabolism in neoplastic diseaseProblem of tumor cell identification in the bone marrowMarrow biopsy in the diagnosis of pyrexia of undetermined originThe relation of bone marrow plasmacytosis to serum proteins in cancer patientsThe frequency of tumor cells in the bone marrow and bloodTHE CLINICAL SIGNIFICANCE OF STERNAL TENDERNESSAbnormalities in calcium metabolism in malignancy; effects of hormone therapy 1 April 1956Volume 44, Issue 4Page: 617-629KeywordsAnemiaArthritisBone marrowCancer treatmentCellsFibroblastsHematology and oncologyHospital medicineHospitalsPathologists ePublished: 1 December 2008 Issue Published: 1 April 1956 PDF downloadLoading ...