Pentamidine and Hypoglycemia
Authors: OM P. GANDA
Journal: Annals of Internal Medicine (1984)

Letters and Corrections1 March 1984Pentamidine and HypoglycemiaOM P. GANDA, M.D.OM P. GANDA, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-100-3-464_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: In a letter, Sharpe (1) describes the interesting case of a patient with Pneumocystis carinii pneumonia who developed hypoglycemia while receiving pentamidine therapy. The author states that he could find only four references to pentamidine-induced hypoglycemia in the literature and that three of the four articles were not readily available.Let me point out that pentamidine-induced hypoglycemia is a phenomenon well documented in the pages of several prominent medical journals. In fact, studies of two of the largest series of patients with pentamidine-induced hypoglycemia were reported in theAnnals. In a 1970 article, Western and colleagues (2),...References1. SHARPE S. Pentamidine and hypoglycemia. Ann Intern Med. 1983;99:128. LinkGoogle Scholar2. WESTERNPERERASCHULTZ RDM. Pentamidine isethionate in the treatment of Pneumocystis carinii pneumonia. Ann Intern Med. 1970;73:695-702. LinkGoogle Scholar3. WALZERPERLKROGSTADRAWSONSCHULTZ PDDPM. Pneumocystis carinii in the United States. Ann Intern Med. 1974;80:84-93. LinkGoogle Scholar4. BOUCHARDSAIREACHCAUBARRÈREGANEVALASSAN PPGIDR. Diabetes mellitus following pentamidine-induced hypoglycemia in humans. Diabetes. 1982;31:40-5. CrossrefMedlineGoogle Scholar5. RERUP C. Drugs producing diabetes through damage of the insulin secreting cells. Pharmacol Rev. 1970;22:485-518. MedlineGoogle Scholar6. KARAMLEWITTYOUNG JPC. Insulinopenic diabetes after rodenticide (vacor) ingestion: a unique model of acquired diabetes in man. Diabetes. 1980;29:971-8. CrossrefMedlineGoogle Scholar7. RELMAN A. How reliable are letters? N Engl J Med. 1983;308:1219-20. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: OM P. GANDA, M.D.Affiliations: Joslin Diabetes Center Harvard Medical School Boston, MA 02215 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byEstudo comparativo da eficácia de isotionato de pentamidina administrada em três doses durante uma semana e de N-metil-glucamina 20mgSbV/kg/dia durante 20 dias para o tratamento da forma cutânea da leishmaniose tegumentar americanaTHE PANCREAS IN AIDSAcquired Immunodeficiency SyndromeInfluence of Pentamidine and Two New Trypanocidal Agents (DAPI, DIPI) on Liver Metabolism of MiceEndocrine Manifestations of Human Immunodeficiency Virus (HIV) InfectionInvestigations on mutagenicity and genotoxicity of pentamidine and some related trypanocidal diamidinesPENTAMIDINE AND HYPOGLYCAEMIAHypoglycemia: Causes, neurological manifestations, and outcome 1 March 1984Volume 100, Issue 3Page: 464-464KeywordsHypoglycemiaPneumocystis carinii pneumonia ePublished: 1 December 2008 Issue Published: 1 March 1984 PDF downloadLoading ...