A COMPARISON OF THE EFFECTIVENESS OF GLUTAMIC ACID HYDROCHLORIDE AND DILUTE HYDROCHLORIC ACID AS THE REPLACEMENT THERAPY IN ANACIDITY MEASURED BY FRACTIONAL GASTRIC ACID TITRATION AND HYDROGEN-ION CONCENTRATION CURVES
Authors: Harry Shay, J. Gershon-Cohen
Journal: Annals of Internal Medicine (1936)

Article1 June 1936A COMPARISON OF THE EFFECTIVENESS OF GLUTAMIC ACID HYDROCHLORIDE AND DILUTE HYDROCHLORIC ACID AS THE REPLACEMENT THERAPY IN ANACIDITY MEASURED BY FRACTIONAL GASTRIC ACID TITRATION AND HYDROGEN-ION CONCENTRATION CURVESHARRY SHAY, M.D., J. GERSHON-COHEN, M.D., M.SC. (Med.)HARRY SHAY, M.D.Search for more papers by this author, J. GERSHON-COHEN, M.D., M.SC. (Med.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-9-12-1628 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptFor the most part, anacidity has been regarded an interesting but scarcely serious medical curiosity. In the absence of gastric carcinoma, or of blood changes suggestive of Addisonian anemia, little consideration has been generally given the anacidity. In fact, since the work of Castle,1it has progressively diminished in importance as a factor in anemia. Clinically, spectacular therapeutic results have been obtained from the administration of hydrochloric acid for the relief of vague, but distressing, digestive symptoms, or in the more obvious gastrogenous diarrhea. Experimentally, time and effort have been lavished upon the study of the response of the achlorhydric...Bibliography1. CASTLEHEATHSTRAUSS WBCWMB: Observations on the etiologic relationship of achylia gastrica to pernicious anemia. IV. A biologic assay of the gastric secretion of patients with pernicious anemia having free hydrochloric acid and that of patients without anemia or with hypochromic anemia having no free hydrochloric acid and of the rôle of intestinal permeability to hemopoietic substances in pernicious anemia, Am. Jr. Med. Sci., 1931, clxxxii, 741. CrossrefGoogle Scholar2. BAYLISSSTARLING WMEH: The mechanism of pancreatic secretion, Jr. Physiol., 1902, xxviii, 325. CrossrefGoogle Scholar3. 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Mr. Fels not only made the grant under which the studies were originated and carried through, but at weekly conferences contributed much of real value to the studies. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byHydrochloric acid therapy in achlorhydriaSalmon Protein as a Source of Histidine, Arginine, Lysine, Cystine, Tyrosine and Tryptophane**Presented to the Scientific Section of the A. Ph. A., Denver meeting, 1942.Gastric anacidity: Its physiologic and clinical significance and its managementGlucose tolerance in anacidity 1 June 1936Volume 9, Issue 12Page: 1628-1638KeywordsAnemiaAttentionBloodDiarrheaGastroenterology and hepatologyHydrochloric acidPernicious anemia ePublished: 1 December 2008 Issue Published: 1 June 1936 PDF downloadLoading ...