AN UNUSUAL NEUROLOGIC SYNDROME IN HODGKIN'S DISEASE
Authors: J E SOKAL, G H GLASER
Journal: Annals of Internal Medicine (1956)

Case Reports1 June 1956AN UNUSUAL NEUROLOGIC SYNDROME IN HODGKIN'S DISEASEJOSEPH E. SOKAL, M.D., GILBERT H. GLASER, M.D.JOSEPH E. SOKAL, M.D.Search for more papers by this author, GILBERT H. GLASER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-44-6-1250 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptNervous system involvement occurs in 10 to 15% of cases of Hodgkin's disease.1In the great majority this consists of compression of the spinal cord or of nerve roots by tumor in vertebrae extending extradurally, or by metastases to spinal meninges. Much rarer are intracranial lesions. These usually consist of involvement of the meninges around the base of the brain, or of impingement on cranial nerves at the foramina of the skull. Invasion of brain substance by Hodgkin's granuloma is extremely rare.2Generalized convulsions are occasionally described in Hodgkin's disease. They usually occur in the terminal stage of the disease...Bibliography1. GrayBakerCottrellSkogland RCABLJE: Hodgkin's disease of the central nervous system, Internat. Clin. 4: 230-236 (Dec.) 1941. Google Scholar2. JacksonParker HF: Hodgkin's disease. V. Involvement of certain other organs, New England J. Med. 233: 369-376, 1945. CrossrefGoogle Scholar3. Von HeckerFischer HW: Zur Kenntnis der Lymphogranulomatöse, Deutsche med. Wchnschr. 48: 482-484, 1922. CrossrefGoogle Scholar4. FeinNewill SBVA: Cerebral Hodgkin's disease. Case report of Hodgkin's granuloma with cerebral invasion, Am. J. Med. 17: 291-294, 1954. CrossrefMedlineGoogle Scholar5. Strong GR: A case of lymphadenoma terminating in meningismus, Lancet 1: 1350-1351, 1911. CrossrefGoogle Scholar6. Paullin JE: Central nervous system manifestations of lymphogranuloma, Internat. Clin. 4: 192-196, 1931. Google Scholar7. SparlingAdamsParker HJRDF: Involvement of the nervous system by malignant lymphoma, Medicine 26: 285-332, 1947. CrossrefMedlineGoogle Scholar8. Serebrjanik B: Lymphogranulomatöse Meningo-Encephalitis und Polyradiculitis, Deutsche Ztschr. f. Nervenh. 129: 103-130, 1933. CrossrefGoogle Scholar9. Kohut H: Unusual involvement of the nervous system in generalized lymphoblastoma, J. Nerv. and Ment. Dis. 103: 9-20, 1946. CrossrefMedlineGoogle Scholar10. VietsHunter HRFT: Lymphoblastomatous involvement of the nervous system, Arch. Neurol. and Psychiat. 29: 1246-1262, 1933. CrossrefGoogle Scholar11. Strange LF: Metastatic carcinoma to the leptomeninges, Tr. Am. Neurol. A. 77: 181-186, 1952. Google Scholar12. Ginsberg S: Hodgkin's disease with predominant localization in the central nervous system, Arch. Int. Med. 39: 571-595, 1927. CrossrefGoogle Scholar13. WinkelmanMoore NWMJ: Lymphogranulomatosis (Hodgkin's disease) of the nervous system, Arch. Neurol. and Psychiat. 45: 304-318, 1941. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Buffalo, New York*Received for publication April 11, 1955.From the Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.†Present address: Roswell Park Memorial Institute, Buffalo 3, New York. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDie LymphogranulomatoseDas Zentralnervensystem bei Krankheiten des Blutes 1 June 1956Volume 44, Issue 6Page: 1250-1259KeywordsBrainHodgkin lymphomaLesionsMeningesNervesNervous systemProteinsSkullSpinal cordVertebrae ePublished: 1 December 2008 Issue Published: 1 June 1956 PDF downloadLoading ...