PHYSICAL FORCES AND THE VASCULAR LINING
Authors: S RODBARD
Journal: Annals of Internal Medicine (1959)

Article1 June 1959PHYSICAL FORCES AND THE VASCULAR LININGSIMON RODBARD, M.D., F.A.C.P.SIMON RODBARD, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-50-6-1339 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptStriking similarities exist between the behavior of rivers and of blood vessels. Rivers erode their banks and deposit sediment to produce islands, thereby modifying the local and even distant geography. Similarly, the bloodstream probably determines certain features of the form and structure of the blood vessels, the heart and the valves.Discovery of the laws of flow, and study of the structural characteristics of the rock of the river bed, have made it possible to harness tremendous forces and to convert catastrophic floods and erosions into the blessings of irrigation and water power. Elucidation of the hydraulic principles involved in...Bibliography1. Gould SE, Ed.: Pathology of the heart, 1953, Charles C Thomas, Springfield, Ill. Google Scholar2. RodbardSaiki SH: Flow through collapsible tubes, Am. Heart J. 46: 715, 1953. CrossrefMedlineGoogle Scholar3. Rodbard S: Vascular modifications induced by flow, Am. Heart J. 51: 926, 1956. CrossrefMedlineGoogle Scholar4. Rodbard S: Physical factors in the progression of stenotic vascular lesions, Circulation 17: 410, 1958. CrossrefMedlineGoogle Scholar5. Rodbard S: Induction of intra-arterial bridges, Abstract Communications delivered at the Third World Congress of Cardiology, Brussels, Belgium, September, 1958. Google Scholar6. MaximowBloom AAW: A textbook of histology, 4th Ed., 1942, W. B. Saunders Co., Philadelphia. Google Scholar7. Weiss P: Erzwingung elementarer Strukturverschiedenheiten am in vitro wachsenden Gewebe, Arch. f. Entwcklngsmechn. d. Organ. 116: 439, 1929. Google Scholar8. Buck RC: Regeneration of tendon, J. Path. and Bact. 66: 1, 1953. CrossrefMedlineGoogle Scholar9. Levy O: Uber den Einfluss von Zug auf die Bildung faserigen Bindegewebes, Arch. f. Entwcklngsmechn. d. Organ. 18: 184, 1904. CrossrefGoogle Scholar10. Stockard CR: An experimental analysis of the origin of blood and vascular endothelium, Am. J. Anat. 1: 174, 1915. Google Scholar11. TownesHolftreter PLJ: Directive movements and selective adhesion of embryonic amphibian cells, J. Exper. Zool. 128: 53, 1955. CrossrefGoogle Scholar12. SchulteTilney HWF: A note on the organization of the venous return with special reference to the iliac veins, Anat. Rec. 3: 555, 1909. CrossrefGoogle Scholar13. Starling EH: The fluids of the body, 1909, Constable Press, London. Google Scholar14. Altschul R: Endothelium, 1954, The Macmillan Company, New York. Google Scholar15. Levy AE: Cowdry's Problems of aging, 1942, The Williams and Wilkins Company, Baltimore. Google Scholar16. LevSaphir MO: Endophlebohypertrophy and phlebosclerosis, Am. J. Path. 28: 401, 1952. MedlineGoogle Scholar17. Crawford T: The healing of puncture wounds in arteries, J. Path. and Bact. 72: 547, 1956. CrossrefGoogle Scholar18. PooleSandersFlorey JCAGHW: Regeneration of aortic endothelium, J. Path. and Bact. 75: 132, 1958. CrossrefGoogle Scholar19. Mehrotra RM: An experimental study of the changes which occur in ligated arteries and veins, J. Path. and Bact. 65: 307, 1953. CrossrefMedlineGoogle Scholar20. Williams G: Experimental studies in arterial ligation, J. Path. and Bact. 72: 569, 1956. CrossrefGoogle Scholar21. RodbardJannotta SF: An analysis of oscillometric pulsations, Circulation 7: 922, 1953. CrossrefMedlineGoogle Scholar22. Binder RC: Fluid mechanics, 2nd Ed., 1949, Prentice-Hall, Inc., New York. Google Scholar23. PattenKramerBarry BMTCA: Valvular action in the embryonic chick heart by localized apposition of endocardial masses, Anat. Rec. 102: 299, 1948. CrossrefMedlineGoogle Scholar24. Kampmeier OF: The genetic history of the valves in the lymphatic system of man, Am. J. Anat. 40: 413, 1928. CrossrefGoogle Scholar25. KampmeierBirch OFCL: The origin and development of the venous valves with particular reference to the saphenous district, Am. J. Anat. 38: 451, 1927. CrossrefGoogle Scholar26. Chang C: On the reaction of the endocardium to the blood stream in the embryonic heart with special reference to the endocardial thickenings in the atrioventricular canal and the bulbus cordis, Am. J. Anat. 51: 253, 1932. Google Scholar27. GouleySickel BAEM: Aortic regurgitation caused by dilatation of the aortic orifice associated with a characteristic valvular lesion, Am. Heart. J. 26: 24, 1943. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Buffalo, N. Y.*Received for publication November 28, 1958.Presented at the Annual Session of The American College of Physicians, Atlantic City, New Jersey, May 1, 1958.From the University of Buffalo Chronic Disease Research Institute, Buffalo, N. Y.The University of Buffalo Chronic Disease Research Institute is supported in part by the New York State Department of Health.†This study was aided by Grant H-2271 (C3) from the National Heart Institute of the U. S. Public Health Service.Requests for reprints should be addressed to Simon Rodbard, M.D., University of Buffalo Chronic Disease Research Institute, 2211 Main Street, Buffalo 14, N. Y. 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