tbuckley/cabot-search huggingface dataset:
Intermittent short duration therapy with fluconazole is effective for tinea capitis
Authors: None Gupta, None Adam, None Hofstader, None Lynde, None Taborda, None Taborda, None Morar, None Dlova, None Raboobee, None Konnikov, None Aboobaker, None Summerbell
Journal: British Journal of Dermatology (1999)

Journal Article Intermittent short duration therapy with fluconazole is effective for tinea capitis Get access A.K. Gupta, A.K. Gupta Division of Dermatology, Department of Medicine, Sunnybrook and Women's College Health Sciences Center (Sunnybrook Site) and the University of Toronto, Toronto N6K 1L6, Canada Aditya K. Gupta E‐mail: agupta@execulink.com Search for other works by this author on: Oxford Academic Google Scholar P. Adam, P. Adam Division of Dermatology, Department of Medicine, St Michael's Hospital and the University of Toronto, Toronto, Canada Search for other works by this author on: Oxford Academic Google Scholar S.L.R. Hofstader, S.L.R. Hofstader Division of Dermatology, Department of Medicine, Sunnybrook and Women's College Health Sciences Center (Women's College Site) and the University of Toronto, Toronto, Canada Search for other works by this author on: Oxford Academic Google Scholar C.W. Lynde, C.W. Lynde Division of Dermatology, Department of Medicine, Toronto Western Hospital and the University of Toronto, Toronto, Canada Search for other works by this author on: Oxford Academic Google Scholar P. Taborda, P. Taborda Division of Dermatology, Instituto Lauro S.Lima, São Paulo, Brazil Search for other works by this author on: Oxford Academic Google Scholar V. Taborda, V. Taborda Division of Dermatology, Instituto Lauro S.Lima, São Paulo, Brazil Search for other works by this author on: Oxford Academic Google Scholar N. Morar, N. Morar Department of Dermatology, King Edward VII Hospital and the University of Natal, Durban, South Africa Search for other works by this author on: Oxford Academic Google Scholar N. Dlova, N. Dlova Department of Dermatology, King Edward VII Hospital and the University of Natal, Durban, South Africa Search for other works by this author on: Oxford Academic Google Scholar N. Raboobee, N. Raboobee Department of Dermatology, King Edward VII Hospital and the University of Natal, Durban, South Africa Search for other works by this author on: Oxford Academic Google Scholar N. Konnikov, N. Konnikov Department of Dermatology, New England Medical Center, Boston, MA, U.S.A. Search for other works by this author on: Oxford Academic Google Scholar ... Show more J. Aboobaker, J. Aboobaker Department of Dermatology, King Edward VII Hospital and the University of Natal, Durban, South Africa Search for other works by this author on: Oxford Academic Google Scholar R.C. Summerbell R.C. Summerbell Ontario Ministry of Health Mycology Laboratory and the Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 141, Issue 2, 1 August 1999, Pages 304–306, https://doi.org/10.1046/j.1365-2133.1999.02981.x Published: 01 August 1999
The Condition We Don't Discuss
Authors: W H Orsinger
Journal: JAMA (2001)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 15523: Absence of Chordae Tendineae near Valve Coaptation Leads to Mitral Regurgitation in Lone Atrial Fibrillation
Authors: Yuji Itabashi, Hirotsugu Mihara, Javier Berdejo, Hiroto Utsunomiya, Ken Matsuoka, Takahiro Shiota
Journal: Circulation (2014)

Introduction: Mitral annuloplasty is performed to treat mitral valve regurgitation (MR) in lone atrial fibrillation (AF) patients. The mechanisms of the significant MR in lone AF patients are not known well. We assessed the hypothesis that absence of chordae tendineae near the mitral valve (MV) coaptation could lead to the significant functional MR in the lone AF patients. Methods: We analyzed 64 patients with a history of AF with greater than 50 % of the left ventricular (LV) ejection fraction, and no organic abnormality of MV. Of these 31 has mild or lesser MR (AF Groups) and 33 has moderate or severe MR (AFMR Group). We also analyzed 33 sinus rhythm patients with normal echocardiographic findings (Sinus Group). Parameters concerning to MV morphology were measured with commercial software. Chordae attaching points (CAPs) nearest from the coaptation line were detected on the anterior mitral leaflet (Figure). Ratio of the length from CAP to coaptation line against that from anterior annulus to coaptation line was calculated as CAP-C/An-C ratio. Results: Mitral annular area (P &lt; 0.05), leaflets surface area (P &lt; 0.05), and CAP-C/An-C ratio (P &lt; 0.05) were larger in the AFMR Group as compared with the AF Group (Table). With multivariate analysis, the correlation factor of significant MR in AF patients was increase in the CAP-C/An-C ratio (Odds ratio (per 1 % increase) = 1.70; p &lt;0.05). Conclusion: The absence of chordae tendineae near the coaptation line represented by larger CAP-C/An-C ratio is related to the functional MR in AF patients with normal LV function.
King's Fund launches quality service GMC tells Privy Council about exam concerns NHS fraud buster named Junior doctors call for more consultants New members elected to medical advisory committee
Authors: Linda Beecham
Journal: BMJ (1998)

# King's Fund launches quality service {#article-title-2}

The King's Fund has launched an independent quality improvement and accreditation organisation, which aims to improve patients' experience of the NHS.

The first part of the Health Quality Service's agenda is to develop new standards of outcome measurement for patient satisfaction, staff motivation, clinical effectiveness, service efficiency, and service access. The service will also enhance the corporate management standards and put particular emphasis on quality of leadership and team work.

Another aim of the new organisation is to encourage other organisations involved in quality in health care to come together, perhaps in an association. From 1999 onwards the service intends to provide quality assurance support for clinical services as well as to organisations.

The service, which has been formed in response to the emphasis in the government's NHS white papers on raising quality standards and working collaboratively, will remain part of the King's Fund. It will gradually become a more separate and specialised service.

Mr Peter Griffiths, the service's executive director, said that it aimed to establish a culture focused …
Argyll-Robertson Pupils In Polyneuritis. Report Of A Case And Theoretical Deductions
Authors: Johannes M. Nielsen, Lloyd E. Verity
Journal: Annals of Internal Medicine (1930)

Article1 January 1930Argyll-Robertson Pupils In Polyneuritis. Report Of A Case And Theoretical DeductionsJOHANNES M. NIELSEN, M.D., LLOYD E. VERITY, M.B.(Tor.), F. A. C. P.JOHANNES M. NIELSEN, M.D.Search for more papers by this author, LLOYD E. VERITY, M.B.(Tor.), F. A. C. P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-3-7-707 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptA case in which Argyll-Robertson pupils developed in the course of a toxic polyneuritis and disappeared with the subsidence of the disease should be recorded for two reasons: 1, clinically their presence in such a case leads to a wrong diagnosis, and 2, their occurrence as a part of polyneuritis throws light on their pathogenesis.A man suffering from chronic cardiovascular-renal disease and chronic pyelonephrosis suffered in six months two attacks of polyneuritis in the second of which his case was studied. Shortly after the onset of the disease, he developed bilateral optic neuritis, Argyll-Robertson pupils, bilateral facial paralysis, signs...References1 INGVAR S: On the Pathogenesis of the Argyll-Robertson Phenomenon. Bull. Johns Hopkins Hospital, 43:363-396. Nov., 1928. Google Scholar2 FUCHS E: Text book of Ophthalmology. Trans, by Alexander Duane, 8th ed., J. B. Lippincott Co., Phila. and London. p. 359. Google Scholar3 MOORE RF: Medical Ophthalmology. P. Blakiston's Son & Co., Phila. p. 135. Google Scholar4 NIELSENSTEGMAN JMLV: A Case of Non-Syphilis Pupillary Inaction. Arch. Neurol. & Psychiat., 16:597. CrossrefGoogle Scholar5 WILSON SA: Problems in Neurology. The Argyll-Robertson Pupil 2:1. May, 1921. Google Scholar6 BROCKIVIMEY SM: Toxic Infectious Disease in the Peripheral and Central Nervous System—So-called Neuronitis. Arch. Neur. & Psychiat., 19:129. Jan., 1928. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Battle Creek, Mich.*From the Battle Creek Sanitarium Clinic. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe Significance of the Unilateral Argyll Robertson Pupil*PupillePupilleInfluenza und Neuritis 1 January 1930Volume 3, Issue 7Page: 707-713KeywordsCardiovascular diseasesParalysisPathogenesis ePublished: 1 December 2008 Issue Published: 1 January 1930 PDF downloadLoading ...
Middle aged women more likely to die after heart attack than men
Authors: Scott Gottlieb
Journal: BMJ (2001)

Middle aged women are more likely than their male peers to die after a heart attack, the results of a new study have shown.

Women younger than age 50 were nearly three times more likely to die than men of the same age regardless of their medical history, the severity of their condition, when they were admitted to hospital, and the hospital treatment they were given, the study's results showed ( Annals of Internal Medicine 2001;134:173-81).

Most previous studies, which have examined long term outcome, have generally …
Mind: Perception and Thought in Their Constructive Aspects
Authors: Paul Schilder
Journal: American Journal of Psychiatry (1950)

This is an exciting book—stimulating, arresting, irritating at times. It was virtually completed by Schilder before his untimely death, but shows evidence toward its end of slackening in the acuteness of reasoning that is present in the earlier parts. One would have enjoyed further discussion of the nature of consciousness and of psychic energy. As he indicates in his foreword, Schilder uses the principles gained in the investigation of the body image in an attempt to define the phenomena of perception and thought. He continues: "I extend the results and methods of modern psychology into a field which so far has not been studied from this point of view. As is every serious worker in this field, I am deeply influenced by Freud. However, guided by my own efforts and by my own material, I have developed my own ideas. Freud's work is an era in psychology. In order to
SYPHILIS AND DIABETES MELLITUS; A LONGTERM CLINICAL STUDY
Authors: Frank S. Perkin
Journal: Annals of Internal Medicine (1944)

Article1 August 1944SYPHILIS AND DIABETES MELLITUS; A LONGTERM CLINICAL STUDYFRANK S. PERKIN, M.D., F.A.C.P.FRANK S. PERKIN, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-21-2-272 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe rôle of syphilis in the etiology of diabetes mellitus has long been a subject of controversy. Isolated cases of the association of the two diseases have appeared in the literature since 1889; some reported apparent improvement in the diabetes following antisyphilitic treatment, whereas others noted a loss of carbohydrate tolerance. The majority of the reports have appeared in the foreign literature where the subject has aroused more interest.These cases were all subject to the just criticisms that they had not been properly studied from a diabetic standpoint, they had not been observed for an adequate period, and were...Bibliography1. PAULLINBOWCOCK JEHM: Treatment of syphilis co-existent with condition simulating diabetes, Jr. Am. Med. Assoc., 1924, lxxxii, 702-705. CrossrefGoogle Scholar2. LEMANN II: Diabetes mellitus, syphilis and the negro, Am. Jr. Med. Sci., 1921, clxii, 226. CrossrefGoogle Scholar3. LEMANN II: Relation of syphilis and diabetes to one another, Am. Jr. Syph., 1929, xiii, 70. Google Scholar4. WILLIAMS JR: Diabetes and syphilis . . . a critical study of relation to each other in 1000 cases of diabetes, N. Y. State Jr. Med., 1941, xli, 252-255. Google Scholar5. MCDANIELMARKSJOSLIN LTHHEP: Diabetes mellitus and syphilis: study of two hundred and fifty-eight cases, Arch. Int. Med., 1940, lxvi, 1011-1051. CrossrefGoogle Scholar6. JOSLINROOTWHITEMARBLE EPHFPA: Treatment of diabetes mellitus, 6th Ed., 1937, Lea and Febiger, Philadelphia. Google Scholar7. WARTHINWILSON ASVF: Coincidence of diabetes and syphilis, Am. Jr. Med. Sci., 1916, clii, 157. CrossrefGoogle Scholar8. NEWBURGHCONN LHJW: A new interpretation of hyperglycaemia in obese middle-aged persons, Jr. Am. Med. Assoc., 1939, cxii, 7. CrossrefGoogle Scholar9. NEWBURGH LH: Control of the hyperglycaemia of obese "diabetics" by weight reduction, ANN. INT. MED., 1942, xvii, 935. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Detroit, Michigan*Received for publication March 20, 1943.From the Diabetic Service, Receiving Hospital, Detroit, Michigan. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAssociation between neurosyphilis and diabetes mellitus: Resurgence of an old problem 神经梅毒与糖尿病的关系：“旧事”再现 1 August 1944Volume 21, Issue 2Page: 272-284KeywordsCarbohydratesDiabetes mellitusEtiologySyphilis Issue Published: 1 August 1944 PDF downloadLoading ...
Improvement in Mortality Risk Prediction After Percutaneous Coronary Intervention Through the Addition of a “Compassionate Use” Variable to the National Cardiovascular Data Registry CathPCI Dataset
Authors: Frederic S. Resnic, Sharon-Lise T. Normand, Thomas C. Piemonte, Samuel J. Shubrooks, Katya Zelevinsky, Ann Lovett, Kalon K.L. Ho
Journal: Journal of the American College of Cardiology (2011)
Endogenous secreted phospholipase A 2 group X regulates cysteinyl leukotrienes synthesis by human eosinophils
Authors: Teal S Hallstrand, Ying Lai, Kathryn A Hooper, Rob C Oslund, William A Altemeier, Gustavo Matute-Bello, Michael H Gelb
Journal: Journal of Allergy and Clinical Immunology (2015)
The Biologic Fundamentals of Radiation Therapy: A Texbook by Friedrich Ellinger, M. D., with a Preface by Maurice Lenz, M. D. English Translation by Reuben Gross, M. D. Elsevier Publishing Company, Inc., New York, 1941. Distributors: Nordeman Publishing Co., 215 Fourth Ave., New York, N. Y. xvi + 360 CP. Price $5.00
Authors: H. M. Wilson
Journal: Cancer Research (1941)
44. AAV Retrograde Transport Potential and Therapeutic Approaches for ALS
Authors: Brian K. Kaspar, Jeronia Vich, Lindsey Christian, Jeffrey D. Rothsten, Fred H. Gage
Journal: Molecular Therapy (2004)

Chronic delivery of molecules to the CNS, such as the spinal cord, for therapeutic purposes has proven difficult. We recently discovered that adeno-associated virus (AAV) can be retrogradely transported efficiently from muscle to motor neurons of the spinal cord allowing a feasible approach to deliver therapies to motor neurons. In our new studies, we have characterized the extent of retrograde transport of the different AAV serotypes including AAV 1–6. All serotypes demonstrate retrograde transport ability with serotypes 1, 2, and 6 showing the highest levels of transport. In quantitative studies of serotype 2, we show approximately 2.5% of total virus injected is retrogradely transported to the spinal cord after quadricep muscle injection.
Abstract 14680: Relationship of Insulin Resistance with Impaired Endothelial Function & Coronary Atherosclerosis among High Risk Individuals Enrolled in a Web-Based Lifestyle Intervention Study: Baptist Employee Healthy Heart Study (BEHHS)
Authors: Ehimen Aneni, Ebenezer Oni, Lara L Roberson, Janisse Post, Gagandeep Nagi, Sameer Shaharyar, Omar Jamal, Shozab S Ali, Rehan Malik, Muhammad Aziz, Adnan Younus, Chen Ye, Beatriz Rosell, Henry Guzman, Ricardo Cury, Jonathan Fialkow, Arthur Agatston, Emir Veledar, Theodore Feldman, Khurram Nasir
Journal: Circulation (2014)

Introduction:  Insulin resistance (IR) has been implicated in the pathogenesis of vascular dysfunction and consequent atherosclerosis however this relationship has been shown to vary with age, population demographics and cardiometabolic risk. We examined the relationship between IR and endothelial function, and coronary atherosclerosis in a relatively young, high risk population free from known CVD.   Methods:  The Baptist Employee Healthy Heart Study (BEHHS) is an ongoing lifestyle intervention study examining the effects of web-based interventions on reducing CVD risk in individuals with metabolic syndrome and type II diabetes mellitus. In addition to administering lifestyle and medical history questionnaires, participants had their Reactive hyperemia index (RHI), a measure endothelial dysfunction (ED) assessed using the EndoPAT 2000 device (Itamar Medical, Israel). Participants older than 35years underwent coronary calcium (CAC) scanning.   Results:  The population consisted of 182 participants, 74% women, 49% Hispanic, with a mean age of 52 ± 9 years (range: 34-72 years). RHI was significantly correlated with HOMA-IR (r = -0.17, p=0.02). Individuals with ED (RHI  2.67) was associated with 3-fold increased risk in ED, whereas no such association was noted with CAC presence.   Conclusions:  The independent relationship of IR with ED in this high CVD risk population supports the assertion that IR is implicated in the development of vascular disease. However, IR does not appear to be associated with burden of coronary atherosclerosis in relatively young high-risk populations. Nonetheless, our findings stress the importance of assessing the impact of lifestyle interventions on IR and to determine if such reductions are associated with improvement in endothelial function.
Money matters: a meta-analytic review of the effects of financial incentives on recovery after closed-head injury
Authors: L M Binder, M L Rohling
Journal: American Journal of Psychiatry (1996)

The authors evaluated the impact of financial incentives on disability, symptoms, and objective findings after closed-head injury.Meta-analysis was used to review the literature. Seventeen reports, covering 18 study groups and a total of 2,353 subjects, contained data from which effect sizes could be calculated. Effect sizes were aggregated after weighting for group size. After discussion, there was 100% agreement between the authors on all calculations.A moderate overall effect size, 0.47, was found. The effect was particularly strong for mild head trauma. The data showed more abnormality and disability in patients with financial incentives despite less severe injuries.Clinical evaluation of patients after closed-head injury, particularly mild head trauma, must include consideration of the effect of financial incentives on symptoms and disability.
Abstract MP35: The American Heart Association’s Life’s Simple 7 and Mortality by Race and Sex in the U.S.: the REasons for Geographic And Racial Differences in Stroke (REGARDS) Cohort
Authors: Mary Cushman, Suzanne E Judd, Virginia J Howard, Neil A Zakai, Brett Kissela, Dawn Kleindorfer, Monika M Safford, George Howard
Journal: Circulation (2014)

Background: The Life’s Simple 7 (LSS) metric is being used by AHA to track the cardiovascular health of the United States population and move toward a 2020 impact goal for improvement. Levels of LSS are associated with mortality risk but there are limited data on whether this association differs by race or sex. Hypothesis: There will be sex and race differences in the association of LSS with mortality in the REGARDS cohort study. Methods: We studied 29,692 REGARDS participants; a population sample of black and white men and women aged 45-98 from across the US, enrolled in 2003-7. Extensive baseline risk factor data were measured in participants’ homes. The 7 LSS components (blood pressure, cholesterol, glucose, body-mass index, smoking, physical activity, diet) were each scored in AHA-defined categories of poor (0 points), intermediate (1 point) and ideal (2 points), and were summed to yield scores ranging from poor for all (0) to ideal for all (14). With 6.4 years follow up there were 3709 deaths. Results: The LSS score was normally distributed with mean (SD) of 7.9 (2.0) in whites and 6.9 (2.0) in blacks. The age, region, income and education adjusted hazard ratio (HR) of death for a 1-unit worse LSS score, stratified by race and sex, are shown in the table. Race and sex interactions were tested individually in separate models. While better scores for LSS were strongly associated with lower mortality, associations differed by race and sex, being weaker in blacks than whites and in men than women. Conclusion: There were large associations of LSS with mortality risk in the REGARDS national sample; 1 point difference in score, corresponding to movement from poor to intermediate or intermediate to ideal for 1 of the 7 factors, was associated with a 16% lower risk of death in white women, 14% lower risk in white men or black women, but only an 11% lower risk in black men. Observed differences in the association of LSS with mortality by race and sex should be considered in efforts to gauge the impact of LSS interventions on health disparities.
Abstract 4916: Difference in Neointimal Growth on the Stent Struts Crossing a Side Branch Between Sirolimus-Eluting Stent and Bare-Metal Stent: An Optical Coherence Tomography Analysis
Authors: Mitsuyasu Terashima, Yoshiaki Nakayama, Yasuyoshi Suzuki, Tsuyoshi Inada, Yasushi Asakura, Tetsuo Matsubara, Hitoshi Matsuo, Keiko Asakura, Etsuo Tsuchikane, Mariko Ehara, Yoshihisa Kinoshita, Masashi Kimura, Kenya Nasu, Osamu Katoh, Takahiko Suzuki
Journal: Circulation (2008)