tbuckley/cabot-search huggingface dataset:
CARDIOLOGIC CRITERIA FOR THE DIAGNOSIS OF RHEUMATIC HEART DISEASE IN THE APPARENTLY HEALTHY SUBJECT
Authors: T N HARRIS
Journal: Annals of Internal Medicine (1947)

Article1 April 1947CARDIOLOGIC CRITERIA FOR THE DIAGNOSIS OF RHEUMATIC HEART DISEASE IN THE APPARENTLY HEALTHY SUBJECTT. N. HARRIS, M.D.T. N. HARRIS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-26-4-554 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe cardiac manifestations of rheumatic fever have a special diagnostic importance for several reasons. First, they determine the importance of the disease to the health and life of the patient. Second, they are the sole manifestations which may persist in the patient after recovery from the acute phase. Finally, they are the only signs of rheumatic disease in the apparently healthy subject on the basis of which a foregoing episode of acute rheumatic fever may be recognized or suspected.The application of cardiac signs to the diagnosis of rheumatic heart disease is complicated, however, by the difficulty in interpreting observed...Bibliography1. RUDOLF RD: Functional heart murmurs, Internat. Clin., 1905, iv, 104. Google Scholar2. SODEMAN WAQuoted by : The systolic murmur, Am. Jr. Med. Sci., 1944, ccviii, 106. Google Scholar3. COOMBS C: Rheumatic heart disease, New York, 1924. Google Scholar4. STILL GF: Common disorders and diseases of childhood, London, 1927, Chapter 37. Google Scholar5. SCOTT RW: The significance of the systolic murmur, Proc. Assoc. Life Ins. Med. Dir. of Am., 1934, xxi, 114. Google Scholar6. FINEBERGSTEUER MHLG: Apical systolic murmurs in children, Am. Heart Jr., 1931, vii, 553. Google Scholar7. WILSON M: Rheumatic fever, New York, 1940, Part II. Google Scholar8. BLANDJONES EFTD: The delayed appearance of heart disease after rheumatic fever, Jr. Am. Med. Assoc., 1939, cxiii, 1380. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Philadelphia, Pennsylvania*Presented at the Twenty-Seventh Annual Session of the American College of Physicians, Philadelphia, May 15, 1946.From the Rheumatic Fever Clinic of the Philadelphia General Hospital and the Department of Pediatrics, University of Pennsylvania.The preparation of this paper was aided by a grant of the Life Insurance Medical Research Fund. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAUSCULTATION OF THE HEART BY PHYSICIANS AND BY COMPUTERApical diastolic murmurs in congenital heart disease 1 April 1947Volume 26, Issue 4Page: 554-560KeywordsCardiovascular therapyHeart diseasesHospitalsPediatricsResearch fundingRheumatic fever ePublished: 1 December 2008 Issue Published: 1 April 1947 PDF downloadLoading ...
Abstract 13877: Comparison of Incidence of Radial Artery Occlusion in Patients Undergoing Trans-radial Intervention With or Without a Sheath: A Prospective Cohort Study
Authors: Ghanshyam Palamaner Subash Shantha, Samir B Pancholy
Journal: Circulation (2014)

Introduction: Sheathless transradial access, by decreasing the profile of hardware, is expected to lower the incidence of radial artery occlusion (RAO). Hypothesis: We sought to compare the risk of RAO in patients undergoing coronary intervention with introducer sheath (SG) or without introducer sheath (SLG). Methods: 1251 consecutive patients undergoing 6 French percutaneous coronary intervention (PCI) between January 1, 2009 and December 31, 2013 in Scranton, PA, formed the study cohort. Radial artery patency was assessed using reverse Barbeau’s test and RAO was confirmed by ultrasonography. Unadjusted, adjusted and propensity matched association between type of radial access (SG vs SLG) and RAO were assessed using logistic regression analysis. Results: Mean age was 65 years, 63% were men 37% were diabetics. 78% attained patent hemostasis (PH). Patients in SG had lower pre-discharge RAO [unadjusted (OR: 0.31, 95% CI: 0.21 - 0.46, P &lt; 0.001), adjusted (OR: 0.10, 95% CI: 0.05 - 0.20, P &lt; 0.001) and propensity matched (OR: 0.20, 95% CI: 0.13 - 0.32, P &lt; 0.001)], 24 hours RAO [unadjusted (OR: 0.20, 95% CI: 0.12 - 0.34, P &lt; 0.001), adjusted (OR: 0.12, 95% CI: 0.06 - 0.24, P &lt; 0.001) and propensity matched (OR: 0.13, 95% CI: 0.07 - 0.25, P &lt; 0.001)] and 30 day RAO [unadjusted (OR: 0.28, 95% CI: 0.14 - 0.54, P &lt; 0.001), adjusted (OR: 0.22, 95% CI: 0.10 - 0.50, P &lt; 0.001) and propensity matched (OR: 0.18, 95% CI: 0.10 - 0.40, P &lt; 0.001)], compared to those in SLG. Spontaneous recanalization rates were significantly higher in SG compared to SLG at 24 hours (62% Vs 38%, P = 0.007) but similar at 30 days (38% Vs 50%, P = 0.338) post PCI. Diabetes diagnosis was an effect modifier for RAO at pre-discharge, 24 hours and 30 days post PCI. Conclusions: Sheath use during radial access for PCI, despite diametrically increasing hardware profile, is associated with less RAO, likely by reducing friction induced intimal trauma. Diabetes is an effect modifier in this association.
The Inositol Polyphosphate 5-Phosphatase PIPP Regulates AKT1-Dependent Breast Cancer Growth and Metastasis
Authors: Lisa M. Ooms, Lauren C. Binge, Elizabeth M. Davies, Parvin Rahman, James R.W. Conway, Rajendra Gurung, Daniel T. Ferguson, Antonella Papa, Clare G. Fedele, Jessica L. Vieusseux, Ryan C. Chai, Frank Koentgen, John T. Price, Tony Tiganis, Paul Timpson, Catriona A. McLean, Christina A. Mitchell
Journal: Cancer Cell (2015)
A Yankee Doctor in Paradise
Authors: Sylvester Maxwell Lambert
Journal: JAMA (1941)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 5599: Serum biomarkers reflecting specific tumor tissue remodeling is a valuable diagnostic tool for lung cancer
Authors: Nicholas Willumsen, Cecilie L. Bager, Diana J. Leeming, Victoria Smith, Claus Christiansen, Morten A. Karsdal, David Dornan, Anne-Christine Bay-Jensen
Journal: Cancer Research (2014)

Abstract Background: The extracellular matrix (ECM) that integrates and surrounds malignant tumors consists of several proteins, amongst other type I collagen and elastin. These structural proteins, as well as intermediate filament (IMF) proteins like vimentin, are remodeled and dysregulated as part of malignant changes. We investigated whether serum biomarkers reflecting ECM and IMF remodeling/dysregulation could be used to differentiate lung cancer patients from healthy controls, other lung pathologies, and other cancer types. Methods: Levels of matrix metalloproteinase (MMP) generated fragments of type I collagen (C1M), of elastin (ELM) and of citrullinated vimentin (VICM) were measured in serum from patients with lung cancer (n=40), gastrointestinal cancer (n=25), prostate cancer (n=14), malignant melanoma (n=7), chronic obstructive pulmonary disease (COPD) (n=13), and idiopathic pulmonary fibrosis (IPF) (n=10), as well as in age-matched controls (n=33). The area under the receiver operating characteristics (AUROC) was calculated for the biomarkers and a diagnostic decision tree was generated from specific cut-off values. Results: Circulating levels of C1M and VICM were significantly elevated in lung cancer patients as compared to healthy controls (AUROC=0.98, p&amp;lt;0.0001) and other cancers (AUROC=0.83 p&amp;lt;0.0001). A trend was detected when comparing lung cancer with COPD+IPF. No difference could be seen for ELM. Interestingly, C1M and VICM were able to identify patients with lung cancer with a positive predictive value of 0.9 and an odds ratio of 40 (95% CI=8.7-186, p&amp;lt;0.0001). Conclusion: This study indentifies biomarkers specifically reflecting ECM and IMF remodeling as applicable for lung cancer patients. We speculate that these markers may aid in diagnosing and characterizing patients with lung cancer. Citation Format: Nicholas Willumsen, Cecilie L. Bager, Diana J. Leeming, Victoria Smith, Claus Christiansen, Morten A. Karsdal, David Dornan, Anne-Christine Bay-Jensen. Serum biomarkers reflecting specific tumor tissue remodeling is a valuable diagnostic tool for lung cancer. [abstract]. In: Proceedings of the 105th Annual Meeting of the American Association for Cancer Research; 2014 Apr 5-9; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2014;74(19 Suppl):Abstract nr 5599. doi:10.1158/1538-7445.AM2014-5599
TCT-452 Drug-Eluting Stents for the Treatment of Chronic Total Occlusion: A Comparison with Sirolimus, Paclitaxel, Zotarolimus (Endeavor Resolute), BiolimusA9, EPC Capture and Everolimus-Eluting Stent: Multicenter Registry in Asia
Authors: Sunao Nakamura, Hisao Ogawa, Jang-Ho Bae, Yeo Cahyadi, Wasan Udayachalerm, Damras Tresukosol, Sudaratana Tansuphaswadikul
Journal: Journal of the American College of Cardiology (2012)
Permanence of Web Page References—Reply
Authors: Renée Crichlow, Nicole Winbush
Journal: JAMA (2005)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Inflammation and Age-Related Macular Degeneration
Authors: Philip L. Penfold
Journal: JAMA (2004)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 3840: Cetuximab-induced testicular toxicity
Authors: Mattan Levi, Aaron Popovtzer, Moran Tzabari, Salomon M. Stemmer, Ruth Shalgi, Irit Ben-Aharon
Journal: Cancer Research (2014)

Abstract Background: Cetuximab, an anti-EGFR monoclonal antibody, is the only targeted therapy approved for the treatment of head and neck squamous cell carcinoma (HNSCC) in patients with locally advanced tumors, in association with radiotherapy, and in patients with recurrent or metastatic disease, in association with cisplatin-based chemotherapy. We aimed to study the effect of cetuximab on testicular function and reserve. Methods: Male mice were injected intraperitoneally with cetuximab (1mg), or cisplatin (8mg/kg) or the combination of both and sacrificed either 1 week or 6 weeks later. Saline-injected mice served as controls. Testes were excised, weighed and further processed. Glutathione and apoptosis assays were performed on 6 weeks samples for determination of oxidative stress. Immunohistochemistry and confocal microscopy were used to study the effect of cetuximab, cisplatin and their combination on the testis histology as well as on the spermatogonial reserve. Results: Cetuximab induced mild apoptosis in the testis. Cisplatin induced enhanced apoptosis and depleted spermatogonial reserve, reflected by reduced DAZL staining (early spermatocyte marker). The combined treatment resulted in further decline in testicular weight compared with cisplatin-only treated mice at 1-month post treatment (p&amp;lt;0.05). Cetuximab enhanced cisplatin-induced oxidative stress, and further depletion of spermatogonial reserve (p&amp;lt;0.05). Conclusions: Cetuximab has a mild effect on testicular reserve. Nevertheless, the addition of cetuximab to cisplatin exacerbates cisplatin-induced testicular toxicity. Citation Format: Mattan Levi, Aaron Popovtzer, Moran Tzabari, Salomon M. Stemmer, Ruth Shalgi, Irit Ben-Aharon. Cetuximab-induced testicular toxicity. [abstract]. In: Proceedings of the 105th Annual Meeting of the American Association for Cancer Research; 2014 Apr 5-9; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2014;74(19 Suppl):Abstract nr 3840. doi:10.1158/1538-7445.AM2014-3840
A memorable patient: A Pyrrhic victory
Authors: D. Kerr
Journal: BMJ (2002)

Cathy, at 17, had come from far away to visit her aunt. When I was called from my bed to see her she was lying semiconscious on a trolley in casualty with a barely perceptible pulse and the telltale rash of fulminating meningococcal septicaemia.

Only a few week previously I had witnessed an 8 year old boy surrender in less than 24 hours to this killer, and I'd been left with a grim expertise on the condition unusual for a recently qualified house doctor. Whether this acquired skill proved helpful to Cathy I was never to find out. My triumph in keeping her alive was a high achievement in 1946, but when my own life events took me outside the hospital world into general practice I had no way of following up her …
FDA Warns Against Breast Milk Drug
Authors: Tracy Hampton
Journal: JAMA (2004)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2022 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Impact of Carvedilol and Metoprolol on Inappropriate Implantable Cardioverter-Defibrillator Therapy
Authors: Martin H. Ruwald, Abeer Abu-Zeitone, Christian Jons, Anne-Christine Ruwald, Scott McNitt, Valentina Kutyifa, Wojciech Zareba, Arthur J. Moss
Journal: Journal of the American College of Cardiology (2013)
A bio-bibliography of Andreas Vesalius.
Authors: Harvey Cushing
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Tetanus Neonatorum—a Curiosity?
Authors: Norman A. Christensen
Journal: Annals of Internal Medicine (1966)

Editorial Notes1 November 1966Tetanus Neonatorum—a Curiosity?NORMAN A. CHRISTENSEN, M.D.NORMAN A. CHRISTENSEN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-65-5-1149 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThough tetanus neonatorum is so rare in most highly developed countries as to be for them a medical curiosity, this is not so for most of the world. Representatives at the recent International Conference on Tetanus*from India (Patel of Bombay), Africa (Rey of Dakar, Senegal), South America (Veronesi of São Paulo, Brazil, and Newell of Colombia), and the islands of the South Pacific (Schofield of New Guinea) reaffirmed the worldwide epidemiologic report of Bytchenko from the World Health Organization (WHO) that tetanus neonatorum is still a major problem in several of the large populous countries of the worldãthat thousands...Reference1. NEWELLLEHMANNLEBLANCOSORIO KWADDRNG: The use of toxoid for the prevention of tetanus neonatorum: final report of a double-blind control field trial. Bull. WHO. In press. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Section of Medicine Mayo Clinic Mayo Foundation Rochester, Minn.*Held in Bern, Switzerland, July 15 through 19, 1966, sponsored by the Swiss Academy of Medicine, and supported by the World Health Organization; Dr. Leo Eckmann, Chairman.*"Guide Lines for the Medical Profession Regarding the Prevention of Tetanus" adopted at the Conference appears on p. 1079 of this issue of the ANNALS. Copies of "Guide Lines" can be obtained from the World Health Organization, Geneva, Switzerland. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 November 1966Volume 65, Issue 5Page: 1149-1149KeywordsEpidemiologyGlobal healthTetanus ePublished: 1 December 2008 Issue Published: 1 November 1966 PDF downloadLoading ...
A Rapid Test for Tumor Growth Inhibitors
Authors: Daniel Laszlo, Cecilie Leuchtenberger
Journal: Cancer Research (1943)

The following report deals with a rapid test for tumor growth inhibitors. Studying the influence of various factors on tumor growth we needed a stand- ardized method that would permit the detection of tumor growth inhibitors on a small number of animals in a short experimental period. Reviewing the litera- ture we did not find such a method. A certain degree of standardization was achieved in a test described by Fleisher and Loeb (6) in 1914. The growth rate of a transplanted adenocarcinoma of the mouse was determined after 4 days' treatment (1 intravenous injection on 4 successive days) by palpa- tion or by weighing of the tumor. In the palpation method drawings of the tumors were made at the start of the experiment and compared with drawings made on the 3rd and 4th day of treatment. In the second test the final weight of the tumors was com- pared with the initial weight (calculated on the basis of drawings made with the aid of weighed models), and the difference expressed the degree of growth in 4 days. With these two tests the authors examined a large number of substances and found, for instance, that casein, colloidal copper, or hirudin retarded tumor growth. MacFadyen and Murphy (13) elaborated a method for detecting tumor growth inhibitors on transplanted tumors with the aid of multiple inoculations. When they transplanted, into the same animal, one untreated tumor fragment and one that had previously been dipped for a definite period into a solution containing inhibitory substances, the latter failed to grow or grew less than the former. The use of one animal for both grafts reduced the influence of variations in host sus- ceptibility but the necessity for application of the test material directly to the transplant seriously limits the usefulness of this method. In extensive studies on chemotherapy Boyland (1-4) tested the action of many compounds on the growth of grafted and primary tumors and attempted (3) to express quantitatively and statistically the effect of inhibiting substances.
Regionalization of Coronary Angioplasty and Travel Distance
Authors: Bruce Y. Lee, Anand Shah, Esther H. Chen
Journal: JAMA (2005)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal