THE USE OF GAMMA GLOBULIN FROM LARGE POOLS OF ADULT BLOOD PLASMA IN CERTAIN INFECTIOUS DISEASES
Authors: J STOKES
Journal: Annals of Internal Medicine (1947)

Article1 March 1947THE USE OF GAMMA GLOBULIN FROM LARGE POOLS OF ADULT BLOOD PLASMA IN CERTAIN INFECTIOUS DISEASESJOSEPH STOKES JR., M.D.JOSEPH STOKES JR., M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-26-3-353 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlthough the protein fraction of blood plasma termed gamma globulin had been well defined previous to World War II, the product itself has recently assumed a greatly enhanced significance as a result of two practical developments of this war period. These are, first, the development by Dr. Edwin J. Cohn, and his co-workers at the Harvard Medical School, of a method of fractionation of plasma into several of its useful components; and, second, the pooling of plasma for fractionation from hundreds or thousands of blood donors under the system of blood collection inaugurated by the American Red Cross.The first...Bibliography1. COHNONCLEYSTRONGHUGHESARMSTRONG EJJLLEWOSH: The characterization of protein fractions of human plasma, Jr. Clin. Invest., 1944, xxiii, 417. CrossrefGoogle Scholar2. ENDERS JF: The concentration of certain antibodies in globulin fractions derived from human blood plasma, Jr. Clin. Invest., 1944, xxiii, 510. CrossrefGoogle Scholar3. Personal communication. Google Scholar4. HENLEHENLESTOKES WGJ: Demonstration of efficiency of vaccination against influenza type A by experimental infection of human beings, Jr. Immunol., 1943, xlvi, 163. Google Scholar5. 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Author, Article, and Disclosure InformationAffiliations: Philadelphia, Pennsylvania*Presented at the Twenty-seventh Annual Session of the American College of Physicians, Philadelphia, May 14, 1946.†These investigations have been carried out as a project of the Commission on Measles and Mumps, Board for the Investigation and Control of Influenza and Other Epidemic Diseases in the Army, Preventive Medicine Service, Office of the Surgeon General, United States Army.We wish to express our great appreciation for the assistance of Mrs. Jeanette H. Levens and Miss Beatrice Payson without whose indispensable contributions in carrying out the technical procedures these investigations could not have been completed. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPost-exposure passive immunisation for preventing rubella and congenital rubella syndromeBlood and Blood ProductsEdwin J. Cohn †Gamma Globulin against Rubella in Pregnancy: I. Prevention of Maternal Rubella by Gamma Globulin and Convalescent Gamma Globulin: a Follow-Up StudyGamma Globulin against Rubella in Pregnancy I. Prevention of Maternal Rubella by Gamma Globulin and Convalescent Gamma Globulin: a Follow-Up StudyEdwin J. Cohn †Edwin J. CohnBlood Grouping, Blood Banking and Blood TransfusionGamma Globulin in Treatment of Chronic Phase of Epidemic Infectious HepatitisBlood and Its DerivativesInfectious HepatitisControl of Epidemics in Public Schools 1 March 1947Volume 26, Issue 3Page: 353-362KeywordsBlood donorsBlood plasmaChemical fractionationGlobulinsInfectious diseasesMeaslesMumpsPlasma proteinsPreventive medicineSurgeons Issue Published: 1 March 1947 PDF downloadLoading ...