THE PARENTERAL ADMINISTRATION OF MAGNESIUM SULPHATE IN HYPERTENSION
Authors: Burton L. Zohman, Bernard Sternberg
Journal: Annals of Internal Medicine (1933)

Article1 November 1933THE PARENTERAL ADMINISTRATION OF MAGNESIUM SULPHATE IN HYPERTENSIONBURTON L. ZOHMAN, M.D., BERNARD STERNBERG, M.D.BURTON L. ZOHMAN, M.D.Search for more papers by this author, BERNARD STERNBERG, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-7-5-643 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlthough magnesium is an important component of all tissues, its proper place in the various processes in the body is but vaguely understood. Outside of the skeletal system where it is found in small quantities, it occurs in all the other organs of the body, at times in even greater quantities than calcium. By the method of Denis,1 the blood stream contains quantities of magnesium ranging from 1.6 to 3.5 mg. per 100 c.c. Mathews 2 found it to be excreted in the urine to the amount of 1 gram per day as magnesium phosphate.A number of interesting and...Bibliography1. DENIS W: Determination of magnesium in blood, Jr. Biol. Chem., 1920, xli, 363-365. CrossrefGoogle Scholar2. MATHEWS AP: Physiological chemistry, a textbook and manual for students, 5th ed., 1930, William Wood and Company, New York, p. 799. Google Scholar3. LOEB J: On the production and suppression of muscular twitchings and hypersensitiveness of the skin by electrolytes, The Decennial Publications, University of Chicago, 1902, x, 1-13. Google Scholar4. MELTZERAUER SJJ: The antagonistic action of calcium upon the inhibitory effect of magnesium, Am. Jr. Physiol., 1908, xxi, 400-419. CrossrefGoogle Scholar5. MEYERGOTTLIEB HHR: Pharmacology, clinical and experimental, 2nd ed., 1926, J. B. Lippincott and Company, Philadelphia, p. 221. Google Scholar6. MELTZERAUER SJJ: Physiological and pharmacological studies of magnesium salts. II. The toxicity of intravenous injections; in particular the effects upon the centers of the medulla oblongata, Am. Jr. Physiol., 1906, xv, 387-405. CrossrefGoogle Scholar7. SOLIS-COHENGITHENS STS: Pharmacotherapeutics, materia medica and drug action, 1928, D. Appleton and Company, New York, p. 1721. Google Scholar8. STANDER HJ: Effect of intravenous administration of magnesium sulphate; experimental studies, Jr. Am. Med. Assoc., 1929, xcii, 631-636. CrossrefGoogle Scholar9. MENDELBENEDICT LBSR: The paths of excretion for inorganic compounds. I-IV. The execretion of magnesium, Am. Jr. Physiol., 1909, xxv, 1-22. Google Scholar10. JOSEPHMELTZER DRSJ: The comparative toxicity of the chlorides of magnesium, calcium, potassium and sodium, Jr. Pharm. and Exper. Therap., 1909-10, i, 1-26. Google Scholar11. MATTHEWSAUSTIN SAWC: Effect of blood calcium level on tolerance to magnesium; hypercalcemia induced by parathyroid hormone, Am. Jr. Physiol., 1927, lxxix, 708-718. CrossrefGoogle Scholar12. WOITASCHEWSKI JB: Experimentelle Untersuchungen und klinische Beobachtungen über die Wirkung schwefelsaurer Magnesia, Arch. f. klin. Chir., 1926, cxli, 135-150. Google Scholar13. MATTHEWSBROOKS SAC: On the action of magnesium sulphate, Jr. Pharm. and Exper. Therap., 1910, ii, 87-99. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Brooklyn, New York*Read before the Brooklyn Society of Internal Medicine May 26, 1933. Received for publication August 12, 1933. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThiocyanate in hypertension 1 November 1933Volume 7, Issue 5Page: 643-652KeywordsBloodCalciumHypertensionMagnesiumPhosphatesRiversUrine ePublished: 1 December 2008 Issue Published: 1 November 1933 PDF downloadLoading ...