THE TREATMENT OF ADDISON'S DISEASE BY THE IMPLANTATION METHOD
Authors: C. F. Kemper
Journal: Annals of Internal Medicine (1945)

Article1 February 1945THE TREATMENT OF ADDISON'S DISEASE BY THE IMPLANTATION METHODC. F. KEMPER, M.D., F.A.C.P.C. F. KEMPER, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-22-2-161 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe implantation of normal suprarenal glands or a potent extract of normal suprarenal glands has been foreshadowed since Addison's disease was first put on a sound clinicopathological basis in 1855. At that time, in his search for an explanation of idiopathic anemia, Thomas Addison as he said "stumbled upon the curious facts" that some asthenic patients of "dingy hue" were found at postmortem examination to have but one demonstrable pathological lesion and that was the destruction of the suprarenal capsules. Obviously he concluded that some significant relationship exists between the clinical syndrome and the pathological changes which he had so...Bibliography1. HARTMANMACARTHURHARTMAN FACGWE: A substance which prolongs the life of adrenalectomized cats, Proc. Soc. Exper. Biol. and Med., 1927, xxv, 69. CrossrefGoogle Scholar2. ROGOFFSTEWART JMGN: The influence of adrenal extracts on the survival period of adrenalectomized dogs, Am. Jr. Physiol., 1928, lxxxiv, 660. CrossrefGoogle Scholar3. SWINGLEPFIFFNER WWJJ: The preparation of an active extract of the suprarenal cortex, Anat. Rec., 1929, xliv, 225. Google Scholar4. GREENROWNTREE CHLG: Further studies in Addison's disease, Proc. Staff Meet. Mayo Clin., 1931, vi, 305. Google Scholar5. Council on Pharmacy and Chemistry, Jr. Am. Med. Assoc., 1943, cxxiii, 351. Google Scholar6. THORN GW: Clinical use of extracts from adrenal cortex, Jr. Am. Med. Assoc., 1944, cxxiii, 11. Google Scholar7. RYNEARSON EH: The treatment of Addison's disease, Jr. Am. Med. Assoc., 1938, cxi, 900. Google Scholar8. KENDALL EC: The function of the adrenal cortex, Jr. Am. Med. Assoc., 1941, cxvi, 2394. CrossrefGoogle Scholar9. FERREBEEREGANATCHLEYLOEB JWCDWRF: Certain effects in the treatment of Addison's disease by desoxycorticosterone esters, Jr. Am. Med. Assoc., 1939, cxiii, 1725. Google Scholar10. THORNKOEPFLEWISOLSEN GWGFRAEF: Carbohydrate metabolism in Addison's disease, Jr. Clin. Invest., 1940, xix, 813. CrossrefGoogle Scholar11. STEIGERREICHSTEIN MT: Desoxysterone 21 oxyprogesteron ans 5.3. oxyätiocholensäure, Heli. Clinn., 1937 (October 20), 1164. Google Scholar12. DEANSLEYPARKS RES: Further experiments on administration of tablets, Lancet, 1938, ii, 606-608. CrossrefGoogle Scholar13. VESTHOWARD SAJE: Clinical experiments with androgens, Jr. Am. Med. Assoc., 1939, cxiii, 1869. Google Scholar14. DI MAIOBIRD MCE: Pellet implantation: the subcutaneous implantation of crystalline pellets of hormone, New England Jr. Med., 1943, ccxxviii, 390. CrossrefGoogle Scholar15. CUTLERPOWERWILDER HHMHRM: Concentration of chloride, sodium and potassium in urine and blood: their diagnostic significance in adrenal insufficiency, Jr. Am. Med. Assoc., 1938, cxi, 117-122. CrossrefGoogle Scholar16. ROBINSONPOWERKEPLER FJMHEJ: Two new procedures to assist in the recognition and exclusion of Addison's disease (a preliminary report), Proc. Staff Meet. Mayo Clin., 1941, xvi, 577. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Denver, Colorado*Delivered before a Regional Meeting of the American College of Physicians, Denver, Colorado, June 24, 1944. Nextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAdrenocortical insufficiencyDie Keimdrüsen und ihre KrankheitenPolyarthritis Resulting from the Treatment of Addison's Disease by DesoxycorticostcroneClinical EndocrinologyIndications for hormonal pellets in the therapy of endocrine and gynecic disorders 1 February 1945Volume 22, Issue 2Page: 161-169KeywordsAutopsyLesionsPernicious anemia ePublished: 1 December 2008 Issue Published: 1 February 1945 Copyright & PermissionsCopyright, 1945, by The American College of PhysiciansPDF downloadLoading ...