SPONTANEOUS MEDIASTINAL EMPHYSEMA
Authors: I D FAGIN, E H SCHWAB
Journal: Annals of Internal Medicine (1946)

Article1 June 1946SPONTANEOUS MEDIASTINAL EMPHYSEMAI. DONALD FAGIN, M.D., F.A.C.P., EDWARD H. SCHWAB, M.D., F.A.C.P.I. DONALD FAGIN, M.D., F.A.C.P.Search for more papers by this author, EDWARD H. SCHWAB, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-24-6-1052 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptKnowledge of the pathology and clinical signs of emphysema of the interstitial tissues of the lung and the mediastinum dates from the time of Laennec, but only during the past decade has it been realized that such emphysema may occur in the absence of thoracic trauma or infection. Full credit is due to Hamman for the recognition and description of mediastinal emphysema of apparently spontaneous origin. In 1934, Hamman1adescribed three cases of this syndrome, later adding four others.1b, 1cSince that time, the medical literature has included sporadic reports of similar cases. The experimental work of Macklin2has contributed...Bibliography1. HAMMAN L: (a) Remarks on the diagnosis of coronary occlusion, Ann. Int. Med., 1934, viii, 417-431. (b) Spontaneous interstitial emphysema of the lungs, Trans. Assoc. Am. Phys., 1937, lii, 311-319. (c) Spontaneous mediastinal emphysema, Bull. Johns Hopkins Hosp., 1939, lxiv, 1-21. Google Scholar2. MACKLIN CC: (a) Pneumothorax with massive collapse from experimental local over-inflation of the lung substance, Canad. Med. Assoc. Jr., 1937, xxxvi, 414-420. (b) Spontaneous mediastinal emphysema: A review and comment, Med. Rec., 1939, cl, 5-7. (c) Transport of air along sheaths of pulmonic blood vessels from alveoli to mediastinum: clinical implication, Arch. Int. Med., 1939, lxiv, 913-926. (d) Impediment to circulation occasioned by pulmonic interstitial emphysema and pneumomediastinum, Jr. Michigan Med. Soc., 1940, xxxix, 756-759. Google Scholar3. LAENNEC R: Traité de l'auscultation médiate, 1831, Brosson and Chandé, Paris. Google Scholar4. ROKITANSKY K: Lehrbuch der pathologischen Anatomie, 1856, Wilhelm Brasmüller, Vienna. Google Scholar5. MÜLLER F: Ueber Emphysem des Mediastinums, Berl. klin. Wchnschr., 1888, xxv, 205-208. Google Scholar6. BALLONFRANCIS HCBD: Consequences of variations in mediastinal pressure: mediastinal and subcutaneous emphysema, Arch. Surg., 1929, xix, 1627-1659. CrossrefGoogle Scholar7. BIERING A(a) : Mediastinal emphysema; case with pneumothorax in newborn with congenital atelectasis, Acta paediat. 1941, xxviii, 367-384. (b) GUMBINER, B., CUTLER M. M.: Spontaneous pneumomediastinum in the newborn, Jr. Am. Med. Assoc., 1941, cxvii, 2050-2054. (c) SMITH A. B. BOWSER J. F.: Spontaneous pneumomediastinum with reports of two cases in infants, Radiology, 1942, xxxviii, 314-319. CrossrefGoogle Scholar8. MCGUIREBEAN JWB: Spontaneous interstitial emphysema of the lungs, Am. Jr. Med. Sci., 1939, cxcvii, 502-509. CrossrefGoogle Scholar9. MOREYSOSMAN JBJC: Spontaneous mediastinal emphysema, Radiology, 1939, xxxii, 19-22. CrossrefGoogle Scholar10. WOLFF BP: Spontaneous interstitial emphysema of the lungs, Ann. Int. Med., 1940, xiii, 1250-1252. Google Scholar11. MATTHEWS E: Spontaneous mediastinal emphysema, New Orleans Med. and Surg. Jr., 1941, xciii, 523-524. Google Scholar12. PINCKNEY MM: Mediastinal emphysema and idiopathic spontaneous pneumothorax, Virginia Med. Monthly, 1941, lxviii, 315-319. Google Scholar13. STYRON CW: Spontaneous mediastinal emphysema, New England Jr. Med., 1941, ccxxv, 908-909. CrossrefGoogle Scholar14. CALDWELL HW: Spontaneous mediastinal emphysema, Jr. Am. Med. Assoc., 1941, cxvi, 301-302. CrossrefGoogle Scholar15. MILLER I: Spontaneous interstitial emphysema of the lungs, Ohio State Med. Jr., 1941, xxxvii, 1056-1059. Google Scholar16. MURPHYZEIS JPLB: Spontaneous interstitial mediastinal emphysema, Jr. Missouri Med. Assoc., 1942, xxxix, 5-7. Google Scholar17. GRIFFIN RJ: (a) Spontaneous pneumothorax, Kentucky Med. Jr., 1941, xxxix, 284-288. (b) A diagnostic sign of interstitial emphysema of the mediastinum, Ann. Int. Med., 1942, xvii, 295-297. Google Scholar18. MEEK EM: Spontaneous mediastinal emphysema, summary and report of a case, South. Med. Jr., 1942, xxxv, 990-992. CrossrefGoogle Scholar19. KELLOGG DS: Spontaneous pneumomediastinum (mediastinal emphysema), Am. Jr. Roentgenol., 1942, xlviii, 510-512. Google Scholar20. DASSENFONGI REG(a) : Hamman syndrome, case, Medicina, 1942, iii, 76-86. (b) FONGI E. G.: Recidivating spontaneous emphysema (Hamman syndrome) with pneumothorax, case, Prensa méd. argent., 1943, xxx, 1980-1985. Google Scholar21. ADCOCK JD: Spontaneous interstitial emphysema of the lung with mediastinal, retroperitoneal, and subcutaneous emphysema, Arch. Int. Med., 1943, lxxi, 650-657. CrossrefGoogle Scholar22. GREENE JA: Unusual sounds emanating from the chest; cause and diagnostic significance of bubbling, clicking, crunching, knocking and tapping sounds; with a report of two cases of interstitial emphysema of lung and mediastinum, Arch. Int. Med., 1943, lxxi, 410-414. CrossrefGoogle Scholar23. LINTZ RM: Spontaneous mediastinal emphysema, Arch. Int. Med., 1943, lxxi, 256-261. CrossrefGoogle Scholar24. MONROEWEBB DSGA: Spontaneous mediastinal emphysema, Canad. Med. Assoc. Jr., 1943, xlviii, 232-235. Google Scholar25. HOFFMANPOBIRSMERLISS AMFWR: The phonocardiogram in spontaneous interstitial emphysema of the mediastinum, Am. Heart Jr., 1943, xxvi, 686-691. CrossrefGoogle Scholar26. ISRAEL JE: Hamman syndrome; case, Rev. Asoc. méd. argent., 1943, lvii, 738-740. Google Scholar27. MILLER H: Spontaneous mediastinal emphysema, Ann. Int. Med., 1944, xxi, 998-1010. Google Scholar28. SCOTT AM: The significance of the anginal syndrome in acute spontaneous pneumomediastinum, Lancet, 1937, i, 1327-1330. CrossrefGoogle Scholar29. SCHWEMLEIN GX: Pulmonic interstitial emphysema and anterior mediastinal emphysema, Ohio State Med. Jr., 1942, xxxviii, 932-934. Google Scholar30. WOLFERTHWOOD CCFC: Angina pectoris, Med. Clin. N. Am., 1930, xiii, 947-967. Google Scholar31. LISTER WA: A case of pericardial knock associated with spontaneous pneumothorax, Lancet, 1928, i, 1225-1226. CrossrefGoogle Scholar32. REESHUGHES WAGS(a) : Wounds of the chest as seen at an advanced operating center, Lancet, 1918, i, 55-59. (b) SMITH S. M. S.: Pericardial knock, Brit. Med. Jr., 1918, i, 78. (c) MUNDEN W. P. H.: Pericardial knock, Brit. Med. Jr., 1918, i, 174. CrossrefGoogle Scholar33. SCADDINGWOOD JGP: Systolic clicks due to left-sided pneumothorax, Lancet, 1939, ii, 1208-1211. CrossrefGoogle Scholar34. FISHER JH: Spontaneous pulmonic interstitial and mediastinal emphysema in infant, Canad. Med. Assoc. Jr., 1941, xliv, 27-29. Google Scholar1. MACKLINMACKLIN MTCC: Malignant interstitial emphysema of the lungs and mediastinum as an important occult complication in many respiratory diseases and other conditions: an interpretation of the clinical literature in the light of laboratory experiment, Medicine, 1944, xxiii, 281-358. CrossrefGoogle Scholar2. HAMMAN L: Mediastinal emphysema, Jr. Am. Med. Assoc., 1945, cxxviii, 1-6. Dr. Hamman herein reports another case of spontaneous mediastinal emphysema, the patient being a 26 year old male. The clinical features were similar to those described in the foregoing discussion, but the electrocardiograph revealed inverted T-waves in the limb leads. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication June 25, 1945.From the Department of Internal Medicine, U. S. Marine Hospital, Galveston, Texas, and the University of Texas School of Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPneumomediastinumClicks and Sounds (Whoops) in Left-Sided PneumothoraxMediastinumChest PainSpontaneous Tension Pneumomediastinum Complicating Pulmonary TuberculosisDie Coronarerkrankungen. Coronarinsuffizienz, Angina pectoris und HerzinfarktCor pulmonaleCor pulmonalePNEUMOMEDIASTINUM: PHYSIOLOGIC OBSERVATIONSCLICKING PNEUMOTHORAX SIMULATING MYOCARDIAL INFARCTIONACUTE SPONTANEOUS MEDIASTINAL EMPHYSEMAMediastinal emphysema complicating tracheotomy and thyroidectomySpontaneous irruption of air from the lungMediastinal Emphysema and Its Occurrence in Artificial PneumoperitoneumMEDIASTINAL EMPHYSEMA OCCURRING WITH THERAPEUTIC PNEUMOPERITONEUM: REPORT OF TEN CASES*MILTON N. TOWBIN, M.D.Acute pulmonary interstitial and mediastinal emphysema (airblock) and pneumothorax in infancy and early childhoodMediastinal EmphysemaAcute pericarditis of benign typeRecurrent spontaneous mediastinal emphysema simulating myocardial infarctionSpontaneous interstitial emphysema of the lung simulating organic heart diseaseSpontaneous mediastinal emphysema with acute right ventricular strain 1 June 1946Volume 24, Issue 6Page: 1052-1072KeywordsArmed forcesClinical pathologyEmphysemaHospital medicineLungs ePublished: 1 December 2008 Issue Published: 1 June 1946 PDF downloadLoading ...