PECULIAR FAMILIAL AND MALIGNANT PHEOCHROMOCYTOMAS OF THE ORGANS OF ZUCKERKANDL
Authors: J E COOK, R W URICH, H G SAMPLE, N W FAWCETT
Journal: Annals of Internal Medicine (1960)

Article1 January 1960PECULIAR FAMILIAL AND MALIGNANT PHEOCHROMOCYTOMAS OF THE ORGANS OF ZUCKERKANDLJ. E. COOK, M.D., R. W. URICH, M.D., H. G. SAMPLE JR., M.D., N. W. FAWCETT, M.D.J. E. COOK, M.D.Search for more papers by this author, R. W. URICH, M.D.Search for more papers by this author, H. G. SAMPLE JR., M.D.Search for more papers by this author, N. W. FAWCETT, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-52-1-126 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptINTRODUCTIONPheochromocytomas of the organs of Zuckerkandl are rare tumors that are primarily benign. We are aware of only three malignant lesions involving these organs previously reported in the literature.8The purpose of this paper is to discuss the familial and malignant aspects of pheochromocytomas, especially of the organs of Zuckerkandl, and to present three case reports.1,, 2, 4, 9, 12, 18PRESENTATIONPheochromocytomas may arise either from the medullary tissues of the adrenals or from chromaffin tissue located elsewhere in the body. The majority of chromaffin tumors occur in the adrenal gland. About 10% of pheochromocytomas occur in extra-adrenal...Bibliography1. CalkinsHoward EJ: Bilateral familial pheochromocytoma with paroxysmal hypertension, J. Clin. Endocrinol. 7: 475, 1947. CrossrefGoogle Scholar2. DavisHullVardell FWJGJG: Pheochromocytoma with neurofibromatosis, Am. J. Med. 8: 131, 1950. CrossrefMedlineGoogle Scholar3. Engelvon Euler AUS: Diagnostic value of increased urinary output of noradrenalin and adrenalin in pheochromocytoma, Lancet 2: 387, 1950. CrossrefMedlineGoogle Scholar4. von EulerStrom USG: Present status of diagnosis and treatment of pheochromocytoma, Circulation 15: 5, 1957. CrossrefMedlineGoogle Scholar5. FlandreauGlushien RHAS: Bilateral pheochromocytoma, Arch. Surg. 76: 62, 1958. CrossrefGoogle Scholar6. GlushienMansuyLittman ASMDS: Pheochromocytoma: its relationship to neurocutaneous syndromes, Am. J. Med. 14: 318, 1953. CrossrefMedlineGoogle Scholar7. Goldenberg M: Chemical screening methods for diagnosis of pheochromocytomas, Am. J. Med. 16: 310, 1954. CrossrefMedlineGoogle Scholar8. HaugBaker WAHW: Malignant paragangliomas of the organs of Zuckerkandl, Arch. Path. 62: 335, 1956. Google Scholar9. HealeyMekalatos FHCJ: Pheochromocytomas and neurofibromatosis, New England J. Med. 258: 540, 1958. CrossrefMedlineGoogle Scholar10. HenrySobel RJC: Chemical determinations of urinary catecholamines, Arch. Int. Med. 100: 196, 1957. CrossrefGoogle Scholar11. HutchinsonEvansDavidson GBJADC: Pitfalls in the diagnosis of pheochromocytoma, Ann. Int. Med. 48: 300, 1958. LinkGoogle Scholar12. KvaleRothManger WFGMWM: Present day diagnosis and treatment of pheochromocytoma, J.A.M.A. 165: 1555, 1957. MedlineGoogle Scholar13. LanceCateLiddleScott EMWBGWHW: Clinical experience with pheochromocytoma, Surg, Gynec. and Obst. 106: 25, 1959. Google Scholar14. Lichenstein BW: Neurofibromatosis: analysis of the total pathologic picture, Arch. Neurol. and Psychiat. 62: 822, 1949. CrossrefMedlineGoogle Scholar15. Weil-MalherbeBone HAD: The estimation of catecholamines in urine by a chemical method, J. Clin. Path. 10: 138, 1957. CrossrefMedlineGoogle Scholar16. Robbins SL: Pheochromocytoma, in Textbook of pathology, 1957, W. B. Saunders Co., Philadelphia. Google Scholar17. RothHightowerBarkerPriestly GMNCNWJT: Familial pheochromocytomas, Arch. Surg. 67: 100, 1953. CrossrefGoogle Scholar18. ThornForshamSheppard GWPHRH: Adrenal medulla, in Principles of internal medicine, 3d Ed., 1958, Harrison, T. R., Editor, The Blakiston Company, New York. Google Scholar19. Soffer LJ: Diseases of the endocrine glands, 2nd Ed., 1956, Lea & Febiger, Philadelphia. Google Scholar20. Orgain ES: Pheochromocytoma: the value of certain tests used routinely in diagnosis, Ann. Int. Med. 43: 1178, 1955. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Colorado Springs, Colorado*Received for publication May 4, 1959.Presented at the Regional Meeting of The American College of Physicians, Colorado Springs, Colorado, January 17, 1959.From the Medical, Surgical and Pathological Services of St. Francis Hospital and Glockner-Penrose Hospital, Colorado Springs, Colorado.Requests for reprints should be addressed to J. E. Cook, M.D., 1422 North Hancock, Colorado Springs, Colorado. 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NEIL SCHIMKE, M.D., WILLIAM H. HARTMANN, M.D.Aortographic Demonstration of Intrathoracic Para-Aortic PhaeochromocytomaMalignant Extra-adrenal PhaeochromocytomaFamilial Pheochromocytoma and Thyroid CarcinomaDAVID S. NOUROK, M.D.Present status of the pathology of the adrenal gland in hypertensionBibliographyDas PhäochromocytomDas Ph�ochromocytom als dominant vererbbare dysgenetische GeschwulstMedical genetics 1960Nonchromaffin-Staining Functional Tumor of the Organs of ZuckerkandlChemical and histochemical observations in benign and malignant phæochromocytomaPHÆOCHROMOCYTOMA CAUSING URETERIC OBSTRUCTION IN A CHILDPheochromocytoma as an Inherited Abnormality 1 January 1960Volume 52, Issue 1Page: 126-133KeywordsAdrenal glandsExcretionLesionsPheochromocytomaSweatTachycardia ePublished: 1 December 2008 Issue Published: 1 January 1960 PDF downloadLoading ...