HOMOZYGOUS HEMOGLOBIN C DISEASE IN A 79 YEAR OLD MAN WITH GOUT
Authors: James W. Ransone, Robert D. Lange
Journal: Annals of Internal Medicine (1957)

Case Reports1 February 1957HOMOZYGOUS HEMOGLOBIN C DISEASE IN A 79 YEAR OLD MAN WITH GOUTJAMES W. RANSONE, ROBERT D. LANGEJAMES W. RANSONESearch for more papers by this author, ROBERT D. LANGESearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-46-2-420 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThough a new form of hemoglobin, hemoglobin C, was reported in 1950 and 1951,1, 2 it was not until 1953 that homozygous hemoglobin C disease was described.3, 4 Since that time the disease has been found repeatedly, but usually in the younger age groups. We wish to report what we believe to be the oldest living person with homozygous hemoglobin C disease—a 79 year old Negro man. Interestingly enough, he also had gout, a condition infrequently reported in the Negro race.CASE REPORTA 79 year old male Negro was admitted to Walter Reed Army Hospital in November, 1954, with...Bibliography1. ItanoNeel HAJV: New inherited abnormality of human hemoglobin, Proc. Nat. Acad. Sc. 36: 613, 1950. CrossrefMedlineGoogle Scholar2. KaplanZuelzerNeel EWWJV: A new inherited abnormality of hemoglobin and its interaction with sickle cell hemoglobin, Blood 6: 1240, 1951. CrossrefMedlineGoogle Scholar3. RanneyLarsonMcCormack HMDLGH: Some clinical, biochemical and genetic observations on hemoglobin C, J. Clin. Investigation 32: 1277, 1953. CrossrefMedlineGoogle Scholar4. SpaetAlwayWard THRHG: Homozygous type "C" hemoglobin, Pediatrics 12: 483, 1953. MedlineGoogle Scholar5. MotulskyPaulDurrum AGMHEL: Paper electrophoresis of abnormal hemoglobins and its clinical applications, Blood 9: 897, 1954. CrossrefMedlineGoogle Scholar6. Ranney HM: Observations on the inheritance of sickle-cell hemoglobin and hemoglobin C, J. Clin. Investigation 33: 1634, 1954. CrossrefMedlineGoogle Scholar7. Gutman AB: Primary and secondary gout, Ann. Int. Med. 39: 1062, 1953. LinkGoogle Scholar8. DiggsKrausMorrisonRudnicki LWAPDBRP: Intraerythrocytic crystals in a white patient with hemoglobin C in the absence of other types of hemoglobin, Blood 9: 1172, 1954. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication October 7, 1955.From the General Medicine Service No. 3 and the Hematology Service, Walter Reed Army Hospital, Walter Reed Army Medical Center, Washington, D. C.Requests for reprints should be addressed to Captain James W. Ransone, MC, Walter Reed Army Hospital, Walter Reed Army Medical Center, Washington 12, D. C. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byTophaceous gout in a patient with sickle cell-thalassemia: case report and review of the literatureSickle cell disease associated with uric acid deposition disease.Secondary gout in hemoglobinopathies: Report of two cases and review of the literatureHOMOZYGOUS HEMOGLOBIN C DISEASE: REPORT OF THREE CASES*KOUICHI R. TANAKA, M.D., GEORGE O. CLIFFORD, M.D. 1 February 1957Volume 46, Issue 2Page: 420-424KeywordsAge groupsAnemiaGoutHematology and oncologyHemoglobinHemolytic anemiaHospital medicinePaper electrophoresisRacial and ethnic issues ePublished: 1 December 2008 Issue Published: 1 February 1957 PDF downloadLoading ...