CLINICAL STUDIES ON BILATERAL COMPLETE ADRENALECTOMY IN PATIENTS WITH SEVERE HYPERTENSIVE VASCULAR DISEASE
Authors: G W THORN, J H HARRISON, J P MERRILL, M G CRISCITIELLO, T F FRAWLEY, J T FINKENSTAEDT
Journal: Annals of Internal Medicine (1952)

Article1 November 1952CLINICAL STUDIES ON BILATERAL COMPLETE ADRENALECTOMY IN PATIENTS WITH SEVERE HYPERTENSIVE VASCULAR DISEASEGEORGE W. THORN, F.A.C.P., J. HARTWELL HARRISON, JOHN P. MERRILL, MODESTINO G. CRISCITIELLO, THOMAS F. FRAWLEY, JOHN T. FINKENSTAEDTGEORGE W. THORN, F.A.C.P.Search for more papers by this author, J. HARTWELL HARRISONSearch for more papers by this author, JOHN P. MERRILLSearch for more papers by this author, MODESTINO G. CRISCITIELLOSearch for more papers by this author, THOMAS F. FRAWLEYSearch for more papers by this author, JOHN T. FINKENSTAEDTSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-37-5-972 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptINTRODUCTIONThe aggravation of hypertensive cardiovascular disease which follows ACTH administration1, 2 lends support to the concept that amelioration of the vascular disease might follow a critical reduction in the function of the adrenal cortex. Further evidence in support of the thesis that the adrenal cortical secretions are involved in the maintenance of hypertension has been presented in another publication by one of us.3The importance of the salt-retaining adrenal hormones in maintaining hypertension is suggested by the authors' experience in the treatment of hypertensive patients who subsequently have developed Addison's disease (figures 1 and 2). Under these circumstances a...Bibliography1. 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