Changes in Cardiopulmonary Functions Related to Abstinence from Smoking
Authors: RICHARD A. KRUMHOLZ
Journal: Annals of Internal Medicine (1965)

Article1 February 1965Changes in Cardiopulmonary Functions Related to Abstinence from SmokingStudies in Young Cigarette Smokers at Rest and Exercise at 3 and 6 Weeks of AbstinenceRICHARD A. KRUMHOLZ, M.D., ROBERT B. CHEVALIER, M.D., JOSEPH C. ROSS, M.D.RICHARD A. KRUMHOLZ, M.D., ROBERT B. CHEVALIER, M.D., JOSEPH C. ROSS, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-62-2-197 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptPhysiologic pulmonary changes associated with smoking are important from many points of view. Previously studies evaluating lung function and exercise oxygen dynamics have been performed in smokers (1-19). Many of these studies have been concerned with the acute changes after the smoking of one or two cigarettes. We recently made measurements of lung volurnes, ventilatory function, and some cardiopulmonary responses to exercise in a group of nonsmokers and found statistically significant differences between the two groups (19). Very similar results were reported by Zwi, Goldman, and Levin (18). The present study was made in order to further evaluate the pulmonary...References1. HENRYFITZHENRY FMJR: Oxygen metabolism of moderate exercise with some observations on effects of tobacco smoking. J. Appl. Physiol. 8: 464, 1950. CrossrefGoogle Scholar2. BICKERMANBARACH HAAL: Effect of cigarette smoking on ventilatory function in patients with bronchial asthma and obstructive pulmonary emphysema. J. Lab. Clin. Med. 43: 455, 1954. MedlineGoogle Scholar3. MOTLEYKUZMAN HLWI: Cigarette smoke: its effect on pulmonary function measurements. Calif. Med. 88: 211, 1958. MedlineGoogle Scholar4. ATTINGERGOLDSTEINSEGAL EOMMMS: Effect of smoking upon mechanics of breathing: I. In normal subjects; II. 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HENSLERGIRON NMDJ: Pulmonary physiological measurements in smokers and nonsmokers. JAMA 186: 885, 1963. CrossrefMedlineGoogle Scholar18. ZWIGOLDMANLEVIN SHIA: Cigarette smoking and pulmonary function in healthy young adults. Amer. Rev. Resp. Dis. 89: 73, 1964. MedlineGoogle Scholar19. KRUMHOLZCHEVALIERROSS RARBJC: Cardio pulmonary function in young smokers: A comparison of pulmonary function measurement and some cardiopulmonary responses to exercise between a group of young smokers and a comparable group of nonsmokers. Ann. Intern. Med. 60: 603, 1964. LinkGoogle Scholar20. OGILVIEFORSTERBLAKEMOREMORTON CMREWSJW: A standardized breath holding technique for the clinical measurement of the diffusing capacity of the lung for carbon monoxide. J. Clin. Invest. 36: 1, 1957. CrossrefMedlineGoogle Scholar21. DALYGIAMMONAROSSFEIGENBAUM WJSTJCH: Effects of pulmonary vascular congestion on postural changes in the perfusion and filling of the pulmonary vascular bed. J. Clin. Invest. 43: 68, 1964. CrossrefMedlineGoogle Scholar22. DUBOISBOTELHOBEDELLMARSHALCOMROE ABSYGWRJH: A rapid plethysmographic method for measuring thoracic gas volume: A comparison with the nitrogen washout method for measuring functional residual capacity in normal subjects. J. Clin. Invest. 35: 322, 1956. CrossrefMedlineGoogle Scholar23. DUBOISBOTELHOCOMROE ABSYJH: A new method for measuring airway resistance in man using a body plethysmograph: values in normal subjects and in patients with respiratory disease. J. Clin. Invest. 35: 327, 1956. CrossrefMedlineGoogle Scholar24. MEADMCILROYSELVERSTONEKRIETE JMBNJBC: Measurement of intraesophageal pressure. J. Appl. Physiol. 7: 491, 1955. CrossrefMedlineGoogle Scholar25. DALYBONDURANT WJS: Direct measurement of respiratory pleural pressure changes in man. J. Appl. Physiol. 18: 513, 1963. CrossrefMedlineGoogle Scholar26. CHEVALIERKRUMHOLZROSS RBRAJC: Effects of carbon monoxide inhalation on the cardiopulmonary responses of nonsmokers to exercise. J. Lab. Clin. Med. 62: 867, 1963. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Indianapolis, IndianaFrom the Department of Medicine and the Heart Research Center, Indiana University Medical Center and the Krannert Heart Research Institute, Marion County General Hospital, Indianapolis, Ind.This study was supported in part by Purdue Farm Cardiac Project Grant OH91 and Research Grants HE-06228 and HE-4080 from the National Heart Institute, National Institutes of Health, U. S. Public Health Service, Bethesda, Md., and in part by the Indiana Heart Association.Dr. Krumholz is a U. S. Public Health Service Postgraduate Research Fellow.Requests for reprints should be addressed to Joseph C. Ross, M.D., Indiana University Medical Center, 1100 W. Michigan St., Indianapolis, Ind. 46207. 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SORLIE, M.SC., RICHARD MASSON, M.D.Diffusing Capacity in Bituminous Coal MinersSmoking Withdrawal ProgrammeCarbon monoxide: Its relationship to air pollution and cigarette smokingThe Benefits of Cessation of SmokingUntersuchungen über die kardiopulmonale Leistungsfähigkeit bei RauchernCigarette Smoking and Changes in Respiratory FindingsManagement and mortality in resection of abdominal aortic aneurysmsMetabolic Changes Associated With the Cessation of Cigarette SmokingA NOTE ON SMOKING AND HEART RATEUntersuchungen über die Ökonomie und Leistungsfähigkeit des Kreislaufs im mittleren LebensalterSmoking and Pulmonary FunctionHypoxemia in Young Asymptomatic Cigarette SmokersManagement of patients with cor pulmonale—Acute and chronicREFERENCES 1 February 1965Volume 62, Issue 2Page: 197-207KeywordsExerciseHeartHospital medicineLongitudinal studiesLungsMedical servicesOxygenPrevention, policy, and public healthResearch grantsRespiratory physiology Issue Published: 1 February 1965 Copyright & PermissionsCopyright ©, 1965, by The American College of PhysiciansPDF downloadLoading ...