THE NUTRITIONAL RÔLE OF CHOLESTEROL IN HUMAN CORONARY ARTERIOSCLEROSIS
Authors: Carl F. Shaffer
Journal: Annals of Internal Medicine (1944)

Article1 June 1944THE NUTRITIONAL RÔLE OF CHOLESTEROL IN HUMAN CORONARY ARTERIOSCLEROSISCARL F. SHAFFER, M.D.CARL F. SHAFFER, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-20-6-948 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptArteriosclerosis, exclusive of the infectious diseases of the arterial system, may be divided pathologically into three types: (1) Atherosclerosis, associated with diseases of the aorta and coronary arteries; (2) arteriolar (or diffuse), sclerosis, associated with arterial hypertension; and (3) Mönckeberg's sclerosis, not clinically significant unless there is superimposed atherosclerosis.Etiology. Hueper, in a review of the etiology of arteriosclerosis, has concluded that the fundamental causal mechanism is an impairment of nutrition and oxygenation of the artery, resulting in damage to the endothelium, increased permeability of the intima, and infiltration of the plasma into the subintimal tissue with later proliferation of...Bibliography1. HUEPER WC: The etiology and the causative mechanism of arteriosclerosis and atheromatosis, Medicine, 1941, xx, 397. CrossrefGoogle Scholar2. ASCHOFF L: Observations concerning the relationship between cholesterol metabolism and vascular disease, Brit. Med. Jr., 1932, ii, 1131. CrossrefGoogle Scholar3. ANITSCHKOW N: Results of experimental studies of atherosclerosis, Verhandl. d. deutsch. path. Gesellsch., 1925, xx, 149. Google Scholar4. LEARY T: Genesis of atherosclerosis, Arch. Path., 1941, xxxii, 507. Google Scholar5. LEARY T: Arteriosclerosis, Bull. New York Acad. Med., 1941, xii, 887. Google Scholar6. WEINHOUSEHIRSCH SE: Atherosclerosis, Arch. Path., 1941, xxx, 856. Google Scholar7. BRUGERROSENKRANTZ MJA: Arteriosclerosis and hypothyroidism; observations on their possible interrelationship, Jr. Clin. Endocrinol., 1942, ii, 176. CrossrefGoogle Scholar8. ROOTGRAYBIEL HFA: Angina pectoris and diabetes mellitus, Jr. Am. Med. Assoc., 1931, xcvi, 925. CrossrefGoogle Scholar9. ROOTGORDONWHITE HFWHPD: Coronary atherosclerosis and diabetes mellitus, Jr. Am. Med. Assoc., 1939, cxiii, 27. CrossrefGoogle Scholar10. MULLER C: Angina pectoris in hereditary xanthomatosis, Arch. Int. Med., 1939, lxiv, 675. CrossrefGoogle Scholar11. LEVY RL: Diseases of the coronary arteries and cardiac pain, 1936, The Macmillan Co., New York, p. 192. Google Scholar12. WILLIUSSMITHSPRAGUE FAHLPH: A study of coronary and aortic sclerosis; incidence and degree in 5,060 consecutive post-mortem examinations, Proc. Staff Meet. Mayo Clin., 1933, viii, 140. Google Scholar13. PARDEE HE: Clinical aspects of the electrocardiogram, 1940, Paul B. Hoeber, Inc., New York. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Omaha, Nebraska*Received for publication December 30, 1942.From the Department of Medicine, Henry Ford Hospital. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byIncidence of Coronary Disease in Patients With Gastroduodenal Ulcer or Upper Gastrointestinal Tract HemorrhageDuodenal Ulcer as a Second DiseaseAtherosclerosis and the Fat Content of the DietCholesterol studies II. Dietary cholesterol and atherosclerosisStudy of Essential Familial Hypercholesterolemia. Relationship of Diet and Blood Cholesterol LevelPropyl-Thiouracil for Angina Pectoris1 1 June 1944Volume 20, Issue 6Page: 948-953KeywordsAtherosclerosisCoronary arteriesEndotheliumEtiologyHospital medicineHypertensionInfectious diseasesNutritionSclerodermaStable coronary artery disease ePublished: 1 December 2008 Issue Published: 1 June 1944 PDF downloadLoading ...