TREATMENT OF PNEUMOCOCCIC PNEUMONIAS WITH SULFAPYRIDINE, SULFATHIAZOLE AND SERUM; ANALYSIS OF THE RESULTS OF SPECIFIC THERAPY AT THE BOSTON CITY HOSPITAL FROM JULY 1939 THROUGH JUNE 1940
Authors: Maxwell Finland, Francis C. Lowell, Elias Strauss
Journal: Annals of Internal Medicine (1941)

Article1 January 1941TREATMENT OF PNEUMOCOCCIC PNEUMONIAS WITH SULFAPYRIDINE, SULFATHIAZOLE AND SERUM; ANALYSIS OF THE RESULTS OF SPECIFIC THERAPY AT THE BOSTON CITY HOSPITAL FROM JULY 1939 THROUGH JUNE 1940MAXWELL FINLAND, M.D., F.A.C.P., FRANCIS C. LOWELL, M.D., ELIAS STRAUSS, M.D.MAXWELL FINLAND, M.D., F.A.C.P.Search for more papers by this author, FRANCIS C. LOWELL, M.D.Search for more papers by this author, ELIAS STRAUSS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-14-7-1184 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe present report deals with the results of specific therapy in the pneumococcic pneumonias of adults at the Boston City Hospital during the second year in which effective chemicals were available. In the preceding year,1specific serums and sulfapyridine each were used separately in a large proportion of the cases, and the results of treatment with each of these agents were quite comparable. The combination of serum and sulfapyridine was used during that year in some of the most severe cases, while a considerable proportion of the cases received neither of these remedies. During the year covered in the present...References1. FINLANDSPRINGLOWELL MWCFC: Specific treatment of the pneumococcic pneumonias: an analysis of the results of serum therapy and chemotherapy at the Boston City Hospital from July 1938 through June 1939, ANN. INT. MED., 1940, xiii, 1567-1593. Google Scholar2. FINLANDDUBLIN MTD: Pneumococcic pneumonias complicating pregnancy and the Puerperium, Jr. Am. Med. Assoc., 1939, cxii, 1027-1032. CrossrefGoogle Scholar3. 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Biol. and Med., 1940, xliii, 92-97. (b) LONG, P. H., and BLISS, E. A.: Bacteriostatic effects of sulfathiazole upon various microörganisms. Its therapeutic effects in experimental pneumococcal infections, Ibid., 324-327. (c) MCKEE, C. M., RAKE, G., GREEP, R. O., and VAN DYKE, H. B.: Therapeutic effect of sulfathiazole and sulfapyridine, Ibid., 417-421. (d) LITCHFIELD, J. T., WHITE, H. J., and MARSHALL, E. K., JR.: The comparative activity of sulfanilamide, sulfapyridine, sulfathiazole and diaminosulfone in Type I pneumococcus infections in mice, Jr. Pharm. and Exper. Therap., 1940, lxix, 166-170. CrossrefGoogle Scholar8. (a) RHEINHOLD J. G. FLIPPIN H. F. SCHWARTZ L. : Observations on the pharmacology and toxicology of sulfathiazole in man, Am. Jr. Med. Sci., 1940, cxcix, 393-401. (b) PEPPER, D. S., and HORACK, H. M.: Crystalline concretions in the renal tubules following sulfathiazole therapy, Ibid., 674-679. (c) LONG, P. H., HAVILAND, J. W., and EDWARDS, L. B.: Acute toxicity, absorption and excretion of sulfathiazole and certain of its derivatives, Proc. Soc. Exper. Biol. and Med., 1940, xliii, 328-332. (d) KNOLL, A. F., and COOPER, F. B.: Clinical urolithiasis medicamentosa due to sulfathiazole, Urol. and Cutan. Rev., 1940, xliv, 292-294. (e) STRAUSS, E., LOWELL, F. C., TAYLOR, F. H. L., and FINLAND, M.: Observations on the absorption, excretion and distribution of sulfanilamide, sulfapyridine, sulfathiazole and sulfamethylthiazole, ANN. INT. MED. (In press.) CrossrefGoogle Scholar9. FINLANDLOWELLSPRING MFCWC: Clinical and laboratory studies on the use of serum and sulfapyridine in the treatment of the pneumococcal pneumonias, New England Jr. Med., 1940, ccxxii, 739-747. CrossrefGoogle Scholar10. PEPPERFLIPPINSCHWARTZLOCKWOOD DSHFLJS: The results of sulfapyridine therapy in 400 cases of typed pneumococcic pneumonia, Am. Jr. Med. Sci., 1939, cxcviii, 22-35. CrossrefGoogle Scholar11. KENNEDYFINLAND PCM: Fatal agranulocytosis from sulfathiazole, Jr. Am. Med. Assoc., 1941, cxvi. (In press.) Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: MAXWELL FINLAND, M.D., F.A.C.P.; FRANCIS C. LOWELL, M.D.; ELIAS STRAUSS, M.D.Affiliations: Boston, Massachusetts*Received for publication August 31, 1940.From the Thorndike Memorial Laboratory, Second and Fourth Medical Services (Harvard), Boston City Hospital, and the Department of Medicine, Harvard Medical School, Boston, Massachusetts. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPNEUMONIA TREATED WITH SULPHA- PYRIDINE AND SULPHATHIAZOLE CONCENTRATION OF THE DRUGS IN THE BLOODLöslichkeitsbestimmungen der Sulfonamidverbindungen. Zur klinischen Frage der Nierenschädigung 1 January 1941Volume 14, Issue 7 Page: 1184-1198 Keywords Clinical laboratories Hospital medicine Medical services Pneumonia Research laboratories ePublished: 1 December 2008 Issue Published: 1 January 1941 PDF downloadLoading ...