COMPARATIVE TESTS OF THYROID FUNCTION
Authors: G B McADAMS, W T SALTER
Journal: Annals of Internal Medicine (1952)

Article1 May 1952COMPARATIVE TESTS OF THYROID FUNCTIONGEORGE B. MCADAMS, WILLIAM T. SALTER, F.A.C.P.GEORGE B. MCADAMSSearch for more papers by this author, WILLIAM T. SALTER, F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-36-5-1198 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn this report are included comparative studies on approximately 45 patients whose thyroid function was appraised by four laboratory tests, in addition to routine clinical observations. These laboratory tests were:(1) Serum "hormonal" iodine (protein-precipitable), S.H.I.(2) Basal metabolic rate, B.M.R.(3) 24-hour uptake of radio-iodide, I131.(4) Thyroid secretory rate, T.S.R., which was determined by the turnover of radio-iodide in the gland, as described by Salter, de Visscher and McAdams.1The chief objective was to validate laboratory means for distinguishing between hyperplasia and hyperfunction of the thyroid in the goitrous patient.The patients studied comprised a wide range of...Bibliography1. Salterde VisscherMcAdams WTMGB: Thyroxine metabolic turnover rate (T.M.R.), Tr. A. Am. Physicians 64: 364, 1951. MedlineGoogle Scholar2. SalterRosenblum WTI: Serum "hormonal" iodine in relation to thyroid function and treatment with adrenocorticotropic hormone (ACTH), J. Endocrinol. 7: 180, 1951. CrossrefMedlineGoogle Scholar3. Salterde VisscherMcAdamsRosenblum WTMGBI: Blood iodine fractions and radioactivity under therapy, J. Clin. Endocrinol. 11: 1512, 1951. CrossrefGoogle Scholar4. Fisher RA: Statistical methods for research workers, 1944, Oliver and Boyd, Edinburgh. Google Scholar5. JaffeOttoman ALRE: Evaluation of radioiodine test for thyroid function, J. A. M. A. 143: 515, 1950. CrossrefMedlineGoogle Scholar6. WernerHamiltonLeiferGoodwin SCHBELD: An appraisal of the radioiodine tracer technique as a clinical procedure in the diagnosis of thyroid disorder, J. Clin. Endocrinol. 10: 1054, 1950. CrossrefGoogle Scholar7. WernerHamilton SCH: Hyperthyroidism without apparent hypermetabolism, J. A. M. A. 186: 450, 1951. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication December 19, 1951.From the Laboratories of Pharmacology and Toxicology, Yale University School of Medicine, New Haven, Connecticut.This paper is the result of studies aided by grants from the Anna Fuller Fund, the Connecticut Cancer Society and the Fluid Research Fund of Yale University School of Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDas toxische Adenom der SchilddrüseKrankheiten der SchilddrüseDie Bestimmung des ?Grundumsatzes im engeren Sinn? in der Diagnostik der Thyreotoxikosen 1 May 1952Volume 36, Issue 5Page: 1198-1205KeywordsLaboratory testsPharmacologyResearch fundingSerum proteinsThyroidToxicology ePublished: 1 December 2008 Issue Published: 1 May 1952 PDF downloadLoading ...