Global Noncommunicable Disease Research: Opportunities and Challenges
Authors: Lindsay M. Jaacks, Mohammed K. Ali, John Bartlett, Gerald S. Bloomfield, William Checkley, Thomas A. Gaziano, Douglas C. Heimburger, Sandeep P. Kishore, Racquel E. Kohler, Kasia J. Lipska, Olivia Manders, Christine Ngaruiya, Robert Peck, Melissa Burroughs Pena, David A. Watkins, Karen R. Siegel, K.M. Venkat Narayan
Journal: Annals of Internal Medicine (2015)

Ideas and Opinions3 November 2015Global Noncommunicable Disease Research: Opportunities and ChallengesLindsay M. Jaacks, PhD, Mohammed K. Ali, MBChB, MSc, MBA, John Bartlett, MD, Gerald S. Bloomfield, MD, MPH, William Checkley, MD, Thomas A. Gaziano, MD, MSc, Douglas C. Heimburger, MD, MS, Sandeep P. Kishore, MD, PhD, Racquel E. Kohler, PhD, MSPH, Kasia J. Lipska, MD, MHS, Olivia Manders, MA, Christine Ngaruiya, MD, DTM&H, Robert Peck, MD, MS, Melissa Burroughs Pena, MD, MS, David A. Watkins, MD, MPH, Karen R. Siegel, PhD, MPH, and K.M. Venkat Narayan, MD, MSc, MBALindsay M. Jaacks, PhDFrom Rollins School of Public Health, Emory University, Atlanta, Georgia; Duke Global Health Institute and Duke Clinical Research Institute, Duke University, Durham, North Carolina; School of Medicine and Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland; Brigham and Women's Hospital and Young Professionals Chronic Disease Network, Boston, Massachusetts; Vanderbilt Institute for Global Health, Vanderbilt University, Nashville, Tennessee;Yale School of Medicine, New Haven, Connecticut; University of North Carolina, Chapel Hill, North Carolina; Center for Global Health, Weill Cornell Medical College, New York, New York; and University of Washington, Seattle, Washington.Search for more papers by this author, Mohammed K. Ali, MBChB, MSc, MBAFrom Rollins School of Public Health, Emory University, Atlanta, Georgia; Duke Global Health Institute and Duke Clinical Research Institute, Duke University, Durham, North Carolina; School of Medicine and Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland; Brigham and Women's Hospital and Young Professionals Chronic Disease Network, Boston, Massachusetts; Vanderbilt Institute for Global Health, Vanderbilt University, Nashville, Tennessee;Yale School of Medicine, New Haven, Connecticut; University of North Carolina, Chapel Hill, North Carolina; Center for Global Health, Weill Cornell Medical College, New York, New York; and University of Washington, Seattle, Washington.Search for more papers by this author, John Bartlett, MDFrom Rollins School of Public Health, Emory University, Atlanta, Georgia; Duke Global Health Institute and Duke Clinical Research Institute, Duke University, Durham, North Carolina; School of Medicine and Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland; Brigham and Women's Hospital and Young Professionals Chronic Disease Network, Boston, Massachusetts; Vanderbilt Institute for Global Health, Vanderbilt University, Nashville, Tennessee;Yale School of Medicine, New Haven, Connecticut; University of North Carolina, Chapel Hill, North Carolina; Center for Global Health, Weill Cornell Medical College, New York, New York; and University of Washington, Seattle, Washington.Search for more papers by this author, Gerald S. Bloomfield, MD, MPHFrom Rollins School of Public Health, Emory University, Atlanta, Georgia; Duke Global Health Institute and Duke Clinical Research Institute, Duke University, Durham, North Carolina; School of Medicine and Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland; Brigham and Women's Hospital and Young Professionals Chronic Disease Network, Boston, Massachusetts; Vanderbilt Institute for Global Health, Vanderbilt University, Nashville, Tennessee;Yale School of Medicine, New Haven, Connecticut; University of North Carolina, Chapel Hill, North Carolina; Center for Global Health, Weill Cornell Medical College, New York, New York; and University of Washington, Seattle, Washington.Search for more papers by this author, William Checkley, MDFrom Rollins School of Public Health, Emory University, Atlanta, Georgia; Duke Global Health Institute and Duke Clinical Research Institute, Duke University, Durham, North Carolina; School of Medicine and Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland; Brigham and Women's Hospital and Young Professionals Chronic Disease Network, Boston, Massachusetts; Vanderbilt Institute for Global Health, Vanderbilt University, Nashville, Tennessee;Yale School of Medicine, New Haven, Connecticut; University of North Carolina, Chapel Hill, North Carolina; Center for Global Health, Weill Cornell Medical College, New York, New York; and University of Washington, Seattle, Washington.Search for more papers by this author, Thomas A. Gaziano, MD, MScFrom Rollins School of Public Health, Emory University, Atlanta, Georgia; Duke Global Health Institute and Duke Clinical Research Institute, Duke University, Durham, North Carolina; School of Medicine and Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland; Brigham and Women's Hospital and Young Professionals Chronic Disease Network, Boston, Massachusetts; Vanderbilt Institute for Global Health, Vanderbilt University, Nashville, Tennessee;Yale School of Medicine, New Haven, Connecticut; University of North Carolina, Chapel Hill, North Carolina; Center for Global Health, Weill Cornell Medical College, New York, New York; and University of Washington, Seattle, Washington.Search for more papers by this author, Douglas C. Heimburger, MD, MSFrom Rollins School of Public Health, Emory University, Atlanta, Georgia; Duke Global Health Institute and Duke Clinical Research Institute, Duke University, Durham, North Carolina; School of Medicine and Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland; Brigham and Women's Hospital and Young Professionals Chronic Disease Network, Boston, Massachusetts; Vanderbilt Institute for Global Health, Vanderbilt University, Nashville, Tennessee;Yale School of Medicine, New Haven, Connecticut; University of North Carolina, Chapel Hill, North Carolina; Center for Global Health, Weill Cornell Medical College, New York, New York; and University of Washington, Seattle, Washington.Search for more papers by this author, Sandeep P. Kishore, MD, PhDFrom Rollins School of Public Health, Emory University, Atlanta, Georgia; Duke Global Health Institute and Duke Clinical Research Institute, Duke University, Durham, North Carolina; School of Medicine and Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland; Brigham and Women's Hospital and Young Professionals Chronic Disease Network, Boston, Massachusetts; Vanderbilt Institute for Global Health, Vanderbilt University, Nashville, Tennessee;Yale School of Medicine, New Haven, Connecticut; University of North Carolina, Chapel Hill, North Carolina; Center for Global Health, Weill Cornell Medical College, New York, New York; and University of Washington, Seattle, Washington.Search for more papers by this author, Racquel E. Kohler, PhD, MSPHFrom Rollins School of Public Health, Emory University, Atlanta, Georgia; Duke Global Health Institute and Duke Clinical Research Institute, Duke University, Durham, North Carolina; School of Medicine and Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland; Brigham and Women's Hospital and Young Professionals Chronic Disease Network, Boston, Massachusetts; Vanderbilt Institute for Global Health, Vanderbilt University, Nashville, Tennessee;Yale School of Medicine, New Haven, Connecticut; University of North Carolina, Chapel Hill, North Carolina; Center for Global Health, Weill Cornell Medical College, New York, New York; and University of Washington, Seattle, Washington.Search for more papers by this author, Kasia J. Lipska, MD, MHSFrom Rollins School of Public Health, Emory University, Atlanta, Georgia; Duke Global Health Institute and Duke Clinical Research Institute, Duke University, Durham, North Carolina; School of Medicine and Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland; Brigham and Women's Hospital and Young Professionals Chronic Disease Network, Boston, Massachusetts; Vanderbilt Institute for Global Health, Vanderbilt University, Nashville, Tennessee;Yale School of Medicine, New Haven, Connecticut; University of North Carolina, Chapel Hill, North Carolina; Center for Global Health, Weill Cornell Medical College, New York, New York; and University of Washington, Seattle, Washington.Search for more papers by this author, Olivia Manders, MAFrom Rollins School of Public Health, Emory University, Atlanta, Georgia; Duke Global Health Institute and Duke Clinical Research Institute, Duke University, Durham, North Carolina; School of Medicine and Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland; Brigham and Women's Hospital and Young Professionals Chronic Disease Network, Boston, Massachusetts; Vanderbilt Institute for Global Health, Vanderbilt University, Nashville, Tennessee;Yale School of Medicine, New Haven, Connecticut; University of North Carolina, Chapel Hill, North Carolina; Center for Global Health, Weill Cornell Medical College, New York, New York; and University of Washington, Seattle, Washington.Search for more papers by this author, Christine Ngaruiya, MD, DTM&HFrom Rollins School of Public Health, Emory University, Atlanta, Georgia; Duke Global Health Institute and Duke Clinical Research Institute, Duke University, Durham, North Carolina; School of Medicine and Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland; Brigham and Women's Hospital and Young Professionals Chronic Disease Network, Boston, Massachusetts; Vanderbilt Institute for Global Health, Vanderbilt University, Nashville, Tennessee;Yale School of Medicine, New Haven, Connecticut; University of North Carolina, Chapel Hill, North Carolina; Center for Global Health, Weill Cornell Medical College, New York, New York; and University of Washington, Seattle, Washington.Search for more papers by this author, Robert Peck, MD, MSFrom Rollins School of Public Health, Emory University, Atlanta, Georgia; Duke Global Health Institute and Duke Clinical Research Institute, Duke University, Durham, North Carolina; School of Medicine and Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland; Brigham and Women's Hospital and Young Professionals Chronic Disease Network, Boston, Massachusetts; Vanderbilt Institute for Global Health, Vanderbilt University, Nashville, Tennessee;Yale School of Medicine, New Haven, Connecticut; University of North Carolina, Chapel Hill, North Carolina; Center for Global Health, Weill Cornell Medical College, New York, New York; and University of Washington, Seattle, Washington.Search for more papers by this author, Melissa Burroughs Pena, MD, MSFrom Rollins School of Public Health, Emory University, Atlanta, Georgia; Duke Global Health Institute and Duke Clinical Research Institute, Duke University, Durham, North Carolina; School of Medicine and Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland; Brigham and Women's Hospital and Young Professionals Chronic Disease Network, Boston, Massachusetts; Vanderbilt Institute for Global Health, Vanderbilt University, Nashville, Tennessee;Yale School of Medicine, New Haven, Connecticut; University of North Carolina, Chapel Hill, North Carolina; Center for Global Health, Weill Cornell Medical College, New York, New York; and University of Washington, Seattle, Washington.Search for more papers by this author, David A. Watkins, MD, MPHFrom Rollins School of Public Health, Emory University, Atlanta, Georgia; Duke Global Health Institute and Duke Clinical Research Institute, Duke University, Durham, North Carolina; School of Medicine and Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland; Brigham and Women's Hospital and Young Professionals Chronic Disease Network, Boston, Massachusetts; Vanderbilt Institute for Global Health, Vanderbilt University, Nashville, Tennessee;Yale School of Medicine, New Haven, Connecticut; University of North Carolina, Chapel Hill, North Carolina; Center for Global Health, Weill Cornell Medical College, New York, New York; and University of Washington, Seattle, Washington.Search for more papers by this author, Karen R. Siegel, PhD, MPHFrom Rollins School of Public Health, Emory University, Atlanta, Georgia; Duke Global Health Institute and Duke Clinical Research Institute, Duke University, Durham, North Carolina; School of Medicine and Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland; Brigham and Women's Hospital and Young Professionals Chronic Disease Network, Boston, Massachusetts; Vanderbilt Institute for Global Health, Vanderbilt University, Nashville, Tennessee;Yale School of Medicine, New Haven, Connecticut; University of North Carolina, Chapel Hill, North Carolina; Center for Global Health, Weill Cornell Medical College, New York, New York; and University of Washington, Seattle, Washington.Search for more papers by this author, and K.M. Venkat Narayan, MD, MSc, MBAFrom Rollins School of Public Health, Emory University, Atlanta, Georgia; Duke Global Health Institute and Duke Clinical Research Institute, Duke University, Durham, North Carolina; School of Medicine and Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland; Brigham and Women's Hospital and Young Professionals Chronic Disease Network, Boston, Massachusetts; Vanderbilt Institute for Global Health, Vanderbilt University, Nashville, Tennessee;Yale School of Medicine, New Haven, Connecticut; University of North Carolina, Chapel Hill, North Carolina; Center for Global Health, Weill Cornell Medical College, New York, New York; and University of Washington, Seattle, Washington.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/M15-1068 Annals Author Insight Video - Lindsay M. Jaacks, PhD In this video, Lindsay M. Jaacks, PhD, offers additional insight into her article, "Global Noncommunicable Disease Research: Opportunities and Challenges." SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Opportunities for collaboration on global noncommunicable disease (NCD) research across international borders and scientific disciplines are increasingly available, coinciding with globalization of science and an unprecedented interest in global health among U.S. students, clinicians, and early-career investigators (1). However, challenges to developing and funding a global NCD research agenda remain. In September 2014, researchers representing 41 institutions, including universities, government agencies, private companies, journals, and foundations in the United States met to discuss the challenges and identify opportunities for moving forward on a global NCD research agenda. Four action items emerged from this conference.Build Bridges Between Communicable Disease and ...References1. Merson MH. University engagement in global health. N Engl J Med. 2014;370:1676-8. [PMID: 24785204] doi:10.1056/NEJMp1401124 CrossrefMedlineGoogle Scholar2. Lamptey P, Dirks R. Building on the AIDS response to tackle noncommunicable disease [Editorial]. Glob Heart. 2012;7:67-71. [PMID: 25691169] doi:10.1016/j.gheart.2012.01.010 CrossrefMedlineGoogle Scholar3. Vermund SH, Narayan KM, Glass RI. Chronic diseases in HIV survivors [Editorial]. Sci Transl Med. 2014;6:241ed14. [PMID: 24944191] doi:10.1126/scitranslmed.3008684 CrossrefMedlineGoogle Scholar4. Syed SB, Dadwal V, Martin G. Reverse innovation in global health systems: towards global innovation flow [Editorial]. Global Health. 2013;9:36. [PMID: 23992598] doi:10.1186/1744-8603-9-36 CrossrefMedlineGoogle Scholar5. Thompson MJ, Huntington MK, Hunt DD, Pinsky LE, Brodie JJ. 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NIH Publication 12-7857. Accessed at www.nhlbi.nih.gov/about/org/globalhealth/resources/OGHStrategicPlan%2007022012%20-%20FINAL.pdf on 29 July 2015. Google Scholar10. Dieleman JL, Graves CM, Templin T, Johnson E, Baral R, Leach-Kemon K, et al. Global health development assistance remained steady in 2013 but did not align with recipients' disease burden. Health Aff (Millwood). 2014;33:878-86. [PMID: 24714869] doi:10.1377/hlthaff.2013.1432 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Rollins School of Public Health, Emory University, Atlanta, Georgia; Duke Global Health Institute and Duke Clinical Research Institute, Duke University, Durham, North Carolina; School of Medicine and Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland; Brigham and Women's Hospital and Young Professionals Chronic Disease Network, Boston, Massachusetts; Vanderbilt Institute for Global Health, Vanderbilt University, Nashville, Tennessee;Yale School of Medicine, New Haven, Connecticut; University of North Carolina, Chapel Hill, North Carolina; Center for Global Health, Weill Cornell Medical College, New York, New York; and University of Washington, Seattle, Washington.Acknowledgment: The authors thank Emory University, Office of the Provost, Rollins School of Public Health, Hubert Department of Global Health, and the Emory Global Diabetes Research Center; the Hubert-Yeargen Center for Global Health at Duke University; and the VECD (Vanderbilt, Emory, Cornell, Duke) Fogarty Global Health Fellowship Program (R25 TW009337) housed at the Vanderbilt Institute for Global Health for their financial contribution to the U.S. Investigators' Network Symposium on Global Non-Communicable Diseases Research, held in Atlanta, Georgia, on 8–9 September 2014.For a list of participants in the U.S. Investigators' Network Symposium on Global Non-Communicable Diseases Research, see the Appendix.Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M15-1068.Corresponding Author: Lindsay M. Jaacks, PhD, Rollins School of Public Health, Claudia Nance Rollins Building, 7040-I, 1518 Clifton Road, Atlanta, GA 30307; e-mail, [email protected]edu.Current Author Addresses: Dr. Jaacks: Rollins School of Public Health, Claudia Nance Rollins Building, 7040-I, 1518 Clifton Road, Atlanta, GA 30307.Dr. Ali: Rollins School of Public Health, Claudia Nance Rollins Building, 7040, 1518 Clifton Road, Atlanta, GA 30307.Drs. Bartlett and Bloomfield: Duke Global Health Institute, 310 Trent Drive, Durham, NC 27710.Dr. Checkley: Johns Hopkins University, Suite 9121, 1800 Orleans Avenue, Baltimore, MD 21205.Dr. Gaziano: Brigham & Women's Hospital, 75 Francis Street, Boston, MA 02115.Dr. Heimburger: Vanderbilt Institute for Global Health, 2525 West End Avenue, Nashville, TN 37212.Dr. Kishore: Yale School of Medicine, 333 Cedar Street, New Haven, CT 06510.Dr. Kohler: University of North Carolina Gillings School of Global Public Health, 135 Dauer Drive, 1101 McGavran-Greenberg Hall, Campus Box #7411, Chapel Hill, NC 27599.Dr. Lipska: Yale School of Medicine, PO Box 208020, New Haven, CT 06520.Ms. Manders: Rollins School of Public Health, Claudia Nance Rollins Building, 7040-L, 1518 Clifton Road, Atlanta, GA 30322.Dr. Ngaruiya: Yale School of Medicine, 464 Congress Avenue, Suite 260, New Haven, CT 06519.Dr. Peck: Weill Cornell Medical College Center for Global Health, 402 East 67th Street, 2nd Floor, New York, NY 10065.Dr. Burroughs Pena: University of California, 505 Parnassus Street, 11th Floor, San Francisco, CA 94143.Dr. Watkins: University of Washington, 325 9th Avenue, Box 359780, Seattle, WA 98104.Dr. Siegel: Rollins School of Public Health, Claudia Nance Rollins Building, 7040-J, 1518 Clifton Road, Atlanta, GA 30322.Dr. Venkat Narayan: Rollins School of Public Health, Claudia Nance Rollins Building, 7049, 1518 Clifton Road, Atlanta, GA 30322.Author Contributions: Conception and design: L.M. Jaacks, M.K. Ali, J. Bartlett, G.S. Bloomfield, W. Checkley, T.A. Gaziano, D.C. Heimburger, S.P. Kishore, R.E. Kohler, K.J. Lipska, O. Manders, C. Ngaruiya, R. Peck, M. Burroughs Pena, D.A. Watkins, K.R. Siegel, K.M. Venkat Narayan.Analysis and interpretation of the data: L.M. Jaacks, K.M. Venkat Narayan.Drafting of the article: L.M. Jaacks, K.M. Venkat Narayan.Critical revision of the article for important intellectual content: L.M. Jaacks, M.K. Ali, J. Bartlett, G.S. Bloomfield, W. Checkley, T.A. Gaziano, D.C. Heimburger, S.P. Kishore, R.E. Kohler, K.J. Lipska, O. Manders, C. Ngaruiya, R. Peck, M. Burroughs Pena, D.A. Watkins, K.R. Siegel, K.M. Venkat Narayan.Final approval of the article: L.M. Jaacks, M.K. Ali, J. Bartlett, G.S. Bloomfield, W. Checkley, T.A. Gaziano, D.C. Heimburger, S.P. Kishore, R.E. Kohler, K.J. Lipska, O. Manders, C. Ngaruiya, R. Peck, M. Burroughs Pena, D.A. Watkins, K.R. Siegel, K.M. Venkat Narayan.Obtaining of funding: J. Bartlett, D.C. Heimburger, K.M. Venkat Narayan.Administrative, technical, or logistic support: G.S. Bloomfield, O. Manders.Collection and assembly of data: L.M. Jaacks, R.E. Kohler, C. Ngaruiya.This article was published online first at www.annals.org on 25 August 2015. PreviousarticleNextarticle Advertisement Annals Author Insight Video - Lindsay M. Jaacks, PhD In this video, Lindsay M. Jaacks, PhD, offers additional insight into her article, "Global Noncommunicable Disease Research: Opportunities and Challenges." 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