The Occurrence of Cystinuria in Healthy Young Men and Women
Authors: Howard B. Lewis
Journal: Annals of Internal Medicine (1932)

Article1 August 1932The Occurrence of Cystinuria in Healthy Young Men and WomenHOWARD B. LEWIS, Ph.D.HOWARD B. LEWIS, Ph.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-6-2-183 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptCystinuria has been considered a relatively rare error of metabolism. Since the report of the first cystine calculus of the urinary tract by Wollaston in 1810, the number of observed cases has been surprisingly small. Kretschmer,1in a review of the occurrence of cystine calculi written in 1916, was able to find reports of only 107 cases of cystine calculi in a period of more than a century since Wollaston's original observation. The present author has reviewed elsewhere2the literature since 1920 and has summarized 71 cases of cystinuria, although calculus formation had not been observed in all of these....References1 KRETSCHMER HL: Cystinuria and cystin stones. With report of a new family of cystinurics. Urol. Cut. Rev., 1916, xx, 1-10. Google Scholar2 LEWIS HB: Cystinuria, a review of some recent investigations. Yale J. Biol. Med., 1931-32, iv, 437-449. Google Scholar3 GARROD AE: Inborn errors of metabolism. London, 2nd. Edition, 1923, 17. Oxford University Press. Google Scholar4 SONDERN EF: Cystinuria. Arch. Diagn., 1911, iv, 267-269. Google Scholar5 EDWARDS HC: Cystinuria with calculus formation. Brit. J. Surg., 1924-25, xii, 345-350. CrossrefGoogle Scholar6 BRANDHARRISBILOON EMMS: Cystinuria. The excretion of a cystine complex which decomposes in the urine with the liberation of free cystine. J. Biol. Chem., 1930, lxxxvi, 315-331. CrossrefGoogle Scholar7 SULLIVAN MX: Studies on the biochemistry of sulphur. II. Further studies on the distinctive reaction for cysteine and cystine. Pub. Health Repts., 1929, xliv, 1421-1428. CrossrefGoogle Scholar8 KLOPFENSTEINLEWIS ARHB: Unpublished data. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: HOWARD B. LEWIS, Ph.D.Affiliations: Ann Arbor, Michigan*From the Department of Physiological Chemistry, University of Michigan. †Received for publication, March 26, 1932. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byEvaluation and Medical Management of Patients with Cystine Nephrolithiasis: A Consensus StatementCalcolosi cistinica: trattamento integrato e personalizzatoAmino-Acid Metabolism in Liver DiseaseFurther Observations on the Hereditary form of PancreatitisTreatment of Cystine Nephrolithiasis with Alpha-Mercapto-PropionylglycineCystinuria: A Review of the Pathophysiology and ManagementHeterozygous cystinuria and urinary lithiasisThe Incidence of Cystinuria in JapanCystinuria and Cystine LithiasisCYSTINURIA AND ITS RELATIONSHIP TO MENTAL RETARDATIONCystinuria: Increased Prevalence in Patients with Mental DiseaseCystinuriaCystine Stones Treated by Surgery and D-PenicillamineHeterozygotes for cystinuriaErkrankungen der HarnwegeCystinuria and Cystine Urolithiasis in ChildhoodErster SitzungstagAminoaciduria After Dietary Loading in Human SubjectsTechnique and Practical Problems: Comparative Studies of the Value of Two Cyanide-Xitroprusside Methods ix the Diagnosis of Cystixuria: Cystinuria in Sweden, Part ixMETABOLIC INVESTIGATION OF PATIENTS WITH RENAL CALCULIMorphologie und Genese der HarnsteineTraitement médical des lithiases urinairesThe Management of Cystinuria and Cystine-Stone DiseaseCalculous diseaseCalculous diseaseGlycinuria, a hereditary disorder associated with nephrolithiasisRenal clearance of lysine in cystinuriaAMINO-ACIDURIA WITH CYSTINOSIS: CASE REPORT WITH DETERMINATION OF URINARY AMINO ACIDS AND OCULAR CYSTINE*PHILIP L. DERN, M.D.Stoffwechsel der Eiweißstoffe und AminosäurenDie angeborenen Stoffwechselanomalien des MenschenREFERENCESCystinosisQUANTITATIVE STUDIES ON THE URINARY CYSTINE IN PATIENTS WITH CYSTINE STONE FORMATION AND IN THEIR RELATIVESCystinuriaThe Riddle of General PracticeTHE GENETICS OF ‘CYSTINURIA’The Effect of Oral Choline in Reducing Cystine Excretion in Cystinuria: A Report of Two CasesPhosphaturie, Oxalurie, Cystinurie, Diaminurie, Aminosurie, AlkaptonurieTHE METABOLISM OF SULFURTHE METABOLISM OF SULFUR 1 August 1932Volume 6, Issue 2 Page: 183-192 ePublished: 1 December 2008 Issue Published: 1 August 1932 PDF downloadLoading ...