Resin Hemoperfusion for Ethchlorvynol
Authors: NEAL L. BENOWITZ
Journal: Annals of Internal Medicine (1980)

Letters1 March 1980Resin Hemoperfusion for EthchlorvynolNEAL L. BENOWITZ, M.D., JON ROSENBERG, M.D., SUSAN POND, M.D.NEAL L. BENOWITZ, M.D.Search for more papers by this author, JON ROSENBERG, M.D.Search for more papers by this author, SUSAN POND, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-92-3-435_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: The article "Resin Hemoperfusion for Treatment of Ethchlorvynol Overdose" by Lynn and coworkers (1) concludes that resin hemoperfusion is a useful procedure in treating ethchlorvynol intoxication. We agree with that conclusion but question some of the assumptions and specific conclusions made in evaluation of the performance of the cartridge.We recently studied resin hemoperfusion for ethchlorvynol overdose at San Francisco General Hospital Medical Center (2). As part of that evaluation we studied ethchlorvynol clearance across and uptake by the Amberlite XAD-4 Cartridge (Extracorporeal Medical Specialties, Inc., King of Prussia, Pennsylvania), and also plasma ethchlorvynol concentrations before, during,...References1. LYNN R, HONIG C, JATLOW P, and KLIGER A. Resin hemoperfusion for treatment of ethchlorvynol overdose. Ann Intern Med. 1979;91:549-53. LinkGoogle Scholar2. BENOWITZ N, ABOLIN C, and TOZER T. Evaluation of resin hemoperfusion for ethchlorvynol overdose. Clin Pharmacol Ther. 1980. In press. CrossrefGoogle Scholar3. TOZER T, WITT L, GEE L, TONG T, and GAMBERTOGLIO J. Evaluation of hemodialysis for ethchlorvynol (Placidyl) overdose. Am J Hosp Pharm. 1974;31:986-9. MedlineGoogle Scholar4. CUMMINS L, MARTIN Y, and SCHERFLING E. Serum and urine levels of ethchlorvynol in man. J Pharm Sci. 1971;60:261-3. CrossrefMedlineGoogle Scholar1. CUMMINS L, MARTIN Y, and SCHERFLING E. Serum and urine levels of ethchlorvynol in man. J Pharm Sci. 1971;60:261-3. CrossrefMedlineGoogle Scholar2. WESTERVELT F. Ethchlorvynol (Placidyl⌖) intoxication: experience with five patients, including treatment with hemodialysis. Ann Intern Med. 1966;64:1229-36. LinkGoogle Scholar1. LYNN R, HONIG C, JATLOW P, and KLIGER A. Resin hemoperfusion for treatment of ethchlorvynol overdose. Ann Intern Med. 1979;91:549-53. LinkGoogle Scholar2. GELFAND M, WINCHESTER J, and KNEPSHIELD J. Treatment of severe drug overdosage with charcoal hemoperfusion. Trans Am Soc Artif Intern Organs. 1977;23:599-604. CrossrefMedlineGoogle Scholar3. ROSENBAUM J, KRAMER M, RAJA R, and BOREYKO C. Resin hemoperfusion: a new treatment for drug intoxication. N Engl J Med. 1971;288:874-7. CrossrefGoogle Scholar4. GLAUSER F, SMITH W, and CALDWELL A. Ethchlorvynol (Placidyl⌖)-induced pulmonary edema. Ann Intern Med. 1976;84:46-8. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: NEAL L. BENOWITZ, M.D.; JON ROSENBERG, M.D.; SUSAN POND, M.D.Affiliations: Division of Clinical Pharmacology San Francisco General Hospital San Francisco, CA 94110 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byHypnotics, sedatives and antipsychoticsExtracorporeal Therapy in the Treatment of IntoxicationCharcoal Hemoperfusion for Treatment of Ethchlorvynol Overdose 1 March 1980Volume 92, Issue 3 Page: 435-437 Keywords Attention Blood plasma Hemoperfusion Intoxication ePublished: 1 December 2008 Issue Published: 1 March 1980 PDF downloadLoading ...