DELAYED DEVELOPMENT OF PERNICIOUS ANEMIA FOLLOWING GASTRECTOMY; HIGH FAMILIAL INCIDENCE OF CANCER: AN ILLUSTRATIVE CASE
Authors: M L CHARLES, L J VORHAUS
Journal: Annals of Internal Medicine (1957)

Case Reports1 December 1957DELAYED DEVELOPMENT OF PERNICIOUS ANEMIA FOLLOWING GASTRECTOMY; HIGH FAMILIAL INCIDENCE OF CANCER: AN ILLUSTRATIVE CASEMARTIN L. CHARLES, M.D., LOUIS J. VORHAUS, M.D.MARTIN L. CHARLES, M.D.Search for more papers by this author, LOUIS J. VORHAUS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-47-6-1266 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe frequent development of pernicious anemia in patients who survive long enough following total gastrectomy is by now a well documented phenomenon. Indeed, as cases were reported and reviewed through the years,1-12 it became apparent that these patients can develop all the features of pernicious anemia, that the anemia usually takes at least two years to develop (and considerably longer in some cases), and that the patients respond well to antipernicious anemia therapy.We feel the present case is of unusual interest not only because of the uncommonly long survival (11½ years) following total gastrectomy for carcinoma of the stomach...Bibliography1. Moynihan BG: A case of complete gastrectomy, Lancet 2: 430-431 (Aug. 12) 1911. CrossrefGoogle Scholar2. Hartman HR: Blood changes in gastrectomized patient simulating those in pernicious anemia, Am. J. M. Sc. 162: 201-206 (Aug.) 1921. CrossrefGoogle Scholar3. RowlandsSimpson RASL: Addisonian anemia following gastrectomy and gastrojejunostomy, Lancet 2: 1202-1209 (Dec. 3) 1932. CrossrefGoogle Scholar4. HartmanEusterman HRGB: Anemia following operation on the stomach, Am. J. Digest. 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