THE ETIOLOGY OF BANTI'S SYNDROME; FURTHER SUPPORT OF THE "CONGESTIVE SPLENOMEGALY" HYPOTHESIS
Authors: C. Lockard Conley, Rodney C. Larcom
Journal: Annals of Internal Medicine (1947)

Case Reports1 August 1947THE ETIOLOGY OF BANTI'S SYNDROME; FURTHER SUPPORT OF THE "CONGESTIVE SPLENOMEGALY" HYPOTHESISC. LOCKARD CONLEY, RODNEY C. LARCOM JR.C. LOCKARD CONLEYSearch for more papers by this author, RODNEY C. LARCOM JR.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-27-2-289 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptBanti, in describing the syndrome which bears his name, attributed the condition to an unknown toxin acting primarily on the spleen. This concept was questioned as early as 1904 by Dock and Warthin,1who described two cases of Banti's syndrome associated with stenosis and calcification of the portal vein. These investigators believed that the histological changes in the spleens of these cases could be explained by prolonged passive congestion and suggested the possibility that the clinical picture might be caused by portal vein stenosis. Subsequently Dürr2observed that sections of the spleens from Banti's original cases showed pathological changes indistinguishable...Bibliography1. DOCKWARTHIN GAS: A clinical and pathological study of two cases of splenic anemia, with early and late stages of cirrhosis, Am. Jr. Med. Sci., 1904, cxxvii, 24-55. CrossrefGoogle Scholar2. DÜRR R: Bantimilz und hepatolienale Fibrose, Beitr. z. path. Anat. u. allg. Path., 1924, lxxii, 418-455. Google Scholar3. WARTHIN AS: The relation of thrombophlebitis of the portal and splenic veins to splenic anemia and Banti's disease, Internat. Clin., 1910, iv, 189-226. Google Scholar4. LARRABEE RC: Chronic congestive splenomegaly and its relationship to Banti's disease, Am. Jr. Med. Sci., 1934, clxxxviii, 745-760. CrossrefGoogle Scholar5. ROUSSELOT LM: Congestive splenomegaly (Banti's syndrome), Bull. N. Y. Acad. Med., 1939, xv, 188-196. Google Scholar6. ROUSSELOTTHOMPSON LMWP: Experimental production of congestive splenomegaly, Proc. Soc. Exper. Biol. and Med., 1939, xl, 705-708. CrossrefGoogle Scholar7. THOMPSON WP: The pathogenesis of Banti's disease, Ann. Int. Med., 1940, xiv, 255-262. Google Scholar8. ROUSSELOT LM: The late phase of congestive splenomegaly (Banti's syndrome) with hematemesis but without cirrhosis of the liver, Surgery, 1940, viii, 34-42. Google Scholar9. RAVENNA P: Splenoportal venous obstruction without splenomegaly, Arch. Int. Med., 1943, lxxii, 786-794. CrossrefGoogle Scholar10. SCHRANK A: Ein seltener Fall von abnormer Pfortaderverengung und -aufspaltung, Klin. Wchnschr., 1940, xix, 1217-1218. CrossrefGoogle Scholar11. FRASERBROWN JAK: A clinical syndrome associated with a rare anomaly of the vena portae system, Surg., Gynec. and Obst., 1944, lxxviii, 520-524. Google Scholar12. TRIMBLEHILL WKJH: Congestive splenomegaly (Banti's disease) due to portal stenosis without hepatic cirrhosis; aneurysms of the splenic artery, Arch. Path., 1942, xxxiv, 423-430. Google Scholar13. BLAKEMORELORD AHJW: A non-suture method of blood vessel anastomosis, Jr. Am. Med. Assoc., 1945, cxxvii, 748-753. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: M.C. Montgomery, Alabama*Received for publication October 15, 1946.From the AAF Regional Hospital, Maxwell Field, Alabama. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byFatal hemorrhage from esophageal varices 1 August 1947Volume 27, Issue 2Page: 289-293KeywordsEtiologyPortal veinsSpleenSplenomegalyStenosisToxins ePublished: 1 December 2008 Issue Published: 1 August 1947 PDF downloadLoading ...