SEVERE REACTIONS TO PARA-AMINOSALICYLIC ACID: A CASE REPORT AND BRIEF REVIEW OF LITERATURE
Authors: D R KORST
Journal: Annals of Internal Medicine (1954)

Case Reports1 May 1954SEVERE REACTIONS TO PARA-AMINOSALICYLIC ACID: A CASE REPORT AND BRIEF REVIEW OF LITERATUREDONALD R. KORSTDONALD R. KORSTSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-40-5-1011 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe purpose of this paper is to report a severe reaction to para-aminosalicylic acid (PAS) and to present a brief review of the literature concerning PAS reactions. Since the introduction of PAS as an antituberculous agent in 1946 by Lehman, based on the work of Bernheim, there has been a worldwide use of the drug in the treatment of tuberculosis. The efficacy of PAS was confirmed by Sievers and Youmans and in 1949 Block et al. suggested that PAS in combination with streptomycin would aid in preventing development of drug resistance. Since then PAS has become accepted as a part...Bibliography1. 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To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication July 6, 1953.From the Departments of Medicine, Veterans Administration Hospital, and University of Wisconsin Hospitals, Madison, Wisconsin.Reviewed in the Veterans Administration and published with the approval of the Chief Medical Director. The statements and conclusions published by the authors are the result of their own study and do not necessarily reflect the opinion or policy of the Veterans Administration. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySerum transaminase levels during treatment with isoniazid, streptomycin and pasLoeffler's Syndrome Due To Para-Aminosalicylic AcidHypersensitivity to para-aminosalicylic acidReactions to Antituberculous Drugs11From the Veterans Administration Hospital, Baltimore, Maryland.Part V: Clinical Applications of Psoralens, and Related Materials: Clinical Experience with the Effect of Oral 8-Methoxy-Psoralen on the Pigmentary Responses of the Skin to Sunlight11From the Department of Dermatology and Syphilology of the New York University-Post-Graduate Medical School (Dr. Marion B. Sulzberger, Chairman) and the Skin and Cancer Unit of the University Hospital, New York, N.Y.COMBINED HYPERSENSITIVITY REACTION TO SODIUM PARA-AMINOSALICYLATE AND ASSOCIATED ANTIBACTERIAL DRUG CONCURRENTLY ADMINISTERED*AARON A. COHEN, M.D., S. H. LAWRENCE, M.D.SEVERE SYSTEMIC REACTIONS TO PARA-AMINOSALICYLIC ACID: A CASE REPORT AND REVIEW OF THE LITERATURE*W. J. ALT, J. R. SPENGLERHome management of pulmonary tuberculosis and other forms 1 May 1954Volume 40, Issue 5Page: 1011-1016KeywordsDrugsHospital medicinePeriodic acid SchiffStreptomycin ePublished: 1 December 2008 Issue Published: 1 May 1954 PDF downloadLoading ...