The<i>Klebsiella-Enterobacter-Serratia</i>Division
Authors: BRUCE W. STEINHAUER
Journal: Annals of Internal Medicine (1966)

Article1 December 1966The Klebsiella-Enterobacter-Serratia DivisionClinical and Epidemiologic CharacteristicsBRUCE W. STEINHAUER, M.D., THEODORE C. EICKHOFF, M.D., JAY WARD KISLAK, M.D., MAXWELL FINLAND, M.D., F.A.C.P.BRUCE W. STEINHAUER, M.D., THEODORE C. EICKHOFF, M.D., JAY WARD KISLAK, M.D., MAXWELL FINLAND, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-65-6-1180 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe gram-negative bacilli that properly belong to the tribe Klebsielleae, or the Klebsiella-Enterobacter-Serratia division of the Enterobacteriaceae, have often been referred to by a confusing variety of other names. Among those frequently found on laboratory reports or in the literature are the Klebsiella group, Klebsiella-Aerobacter, A. aerogenes, Aerobacter group, Friedländer's bacillus, and coli-aerogenes. Many clinicians as well as medical microbiologists have, therefore, found it difficult to maintain a working understanding of the interrelationships of these bacteria and the characteristics of the infections they cause.It has been recognized for several decades that the capsules ofKlebsiellaorganisms are carbohydrate in...References1. EDWARDSFIFE PRMA: Capsule types of Klebsiella. J. Infect. Dis. 91: 92, 1952. CrossrefMedlineGoogle Scholar2. JULIANELLE LA: A biological classification of Encapsulatus pneumoniae (Friedländer's bacillus). J. Exp. Med. 44: 113, 1926. CrossrefMedlineGoogle Scholar3. GOSLINGSSNIJDERS WREP: Untersuchungen über das Scleroma respiratorium (Sklerom); die antigene Struktur der Skleromstamme im Vergleich mit den anderen Kapselbacterien. Zbl. Bakt. [Orig.] 136: 1, 1936. Google Scholar4. EDWARDS PR: Relationships of the encapsulated bacilli with special reference to Bact. aerogenes. J. Bact. 17: 339, 1929. CrossrefMedlineGoogle Scholar5. KAUFFMANN F: On the serology of the Klebsiella group. Acta Path. Microbiol. Scand. 26: 381, 1949. CrossrefGoogle Scholar6. FINLANDJONESBARNES MWFMW: Occurrence of serious bacterial infections since introduction of antibacterial agents. JAMA 170: 2188, 1959. CrossrefMedlineGoogle Scholar7. FINLAND M: Treatment of pneumonia and other serious infections. New Eng. J. Med. 263: 207, 1960. CrossrefMedlineGoogle Scholar8. YOW EM: Clinical significance of rising incidence of infections due to gram-negative bacilli. Postgrad. Med. 17: 413, 1955. CrossrefMedlineGoogle Scholar9. ROGERS DE: The changing pattern of life-threatening microbial disease. New Eng. J. Med. 261: 677, 1959. CrossrefMedlineGoogle Scholar10. BARBER M: Hospital infection yesterday and today. J. Clin. Path. 14: 2, 1961. CrossrefMedlineGoogle Scholar11. FINLANDBARNES MMW: To be published. Google Scholar12. EICKHOFFSTEINHAUERFINLAND TCBWM: The Klebsiella-Enterobader-Serratia division: biochemical and serologic characteristics and susceptibility to antibiotics. Ann. Intern. Med. 65: 1163, 1966. LinkGoogle Scholar13. EWING WH: An outline of nomenclature for the family Enterobacteriaceae. Int. Bull. Bact. Nomenclature Taxon. 13: 95, 1963. Google Scholar14. EWINGEDWARDS WHPR: The principal divisions and groups of Enterobacteriaceae and their differentiation. Int. Bull. Bact. Nomenclature Taxon. 10: 1, 1960. Google Scholar15. EDWARDSEWING PRWH: Identification of Enterobacteriacae, 2nd ed. Burgess, Minn., 1962. Google Scholar16. STEERSFOLTZGRAVES EELBS: Inocula replicating apparatus for routine testing of bacterial susceptibility to antibiotics. Antibiot. Chemother. (N. Y.) 9: 307, 1959. Google Scholar17. WEILBENJAMINSONDEGUZMAN AJMABC: The Klebsiella-Aerobacter-Serratia division: its role in common infections of man. Trans. N. Y. Acad. Sci. 27: 65, 1964. CrossrefMedlineGoogle Scholar18. EDWARDSFIFE PRMA: Studies on the Klebsiella-Aerobacter group of bacteria. J. Bact. 70: 382, 1955. CrossrefMedlineGoogle Scholar19. ElSENBERGO'LOUGHLINFLIPPIN GMJMHF: Distribution and in vitro antibiotic susceptibility of Klebsiella (Kauffmann). J. Lab. Clin. Med. 43: 707, 1954. MedlineGoogle Scholar20. WEISSEISENBERGSPIVACKNADELKAYSERSATHAVARAFLIPPIN WGMAJHLSHF: Klebsiella in respiratory disease. Ann. Intern. Med. 45: 1010, 1956. LinkGoogle Scholar21. ØRSKOV I: Serologic investigations in the Klebsiella group. 2. Occurrence of Klebsiella in sputa. Acta Path. Microbiol. Scand. 36: 454, 1955. CrossrefMedlineGoogle Scholar22. ØRSKOV I: Nosocomial infections with Klebsiella in lesions of the urinary tract. Acta Path. Microbiol. Scand. Suppl. 93: 259, 1952. Google Scholar23. ØRSKOV I: Nosocomial infections with Klebsiella in lesions of the urinary tract. II. Acta Path. Microbiol. Scand. 35: 194, 1954. CrossrefMedlineGoogle Scholar24. FOSTERBRAGG WDJ: Biochemical classification of Klebsiella correlated with the severity of the associated disease. J. Clin. Path. 15: 478, 1962. CrossrefMedlineGoogle Scholar25. DARRELLHURDLE JHAD: Identification and clinical significance of Klebsiella species in chest infections. J. Clin. Path. 17: 617, 1964. CrossrefMedlineGoogle Scholar26. COWANSTEELSHAWDUGUID STKJCJP: A classification of the Klebsiella group. J. Gen. Microbiol. 23: 601, 1960. CrossrefMedlineGoogle Scholar27. MAIZTEGUIBIEGELEISENCHERRYKASS JIJZWBEH: Bacteremia due to gram-negative rods. A clinical, bacteriologic, serologic and immunofluorescent study. New Eng. J. Med. 272: 222, 1965. CrossrefMedlineGoogle Scholar28. MCCABEJACKSON WRGG: Gram-negative bacteremia. I. Etiology and ecology. Arch. Intern. Med. (Chicago) 110: 847, 1962. CrossrefGoogle Scholar29. WEILSPINK MHWW: The shock syndrome associated with bacteremia due to gram-negative bacilli. Arch. Intern. Med. (Chicago) 101: 184, 1958. CrossrefGoogle Scholar30. WEILSHUBINBIDDLE MHHM: Shock caused by gram-negative microorganisms. Analysis of 169 cases. Ann. Intern. Med. 60: 384, 1964. LinkGoogle Scholar31. MCHENRYMARTINWELLMAN MCWJWE: Bacteremia due to gram-negative bacilli. Review of 113 cases encountered in the five-year period 1955 through 1959. Ann. Intern. Med. 56: 207, 1962. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Boston, Massachusetts, and Atlanta, GeorgiaFrom the Thorndike Memorial Laboratory, Second and Fourth (Harvard) Medical Services, Boston City Hospital and the Department of Medicine, Harvard Medical School, Boston, Mass., and the Epidemiology Branch, Communicable Disease Center, U. S. Public Health Service, Atlanta, Ga.This study was aided by grants AI00023 and TI-AI00068, the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.Drs. Steinhauer, Eickhoff, and Kislak were Research Fellows in Medicine, Thorndike Memorial Laboratory and Harvard Medical School.Requests for reprints should be addressed to Maxwell Finland, M.D., Thorndike Memorial Laboratory, Boston City Hospital, Boston, Mass. 02118. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByLiver abscess caused by Klebsiella pneumoniae in a red-footed tortoiseThe Epidemiology of Alcohol Abuse and PneumoniaIdentification of Species and Capsular Types of Klebsiella Clinical Isolates, with Special Reference to Klebsiella planticolaSerratia Bacteremia: A Review of 44 EpisodesMultiply Beta-lactam Resistant Enterobacter cloacae Infections Linked to the Environmental Flora in a Unit for Cardiothoracic and Vascular SurgeryComparison of biochemical and serological typing results and antimicrobial susceptibility patterns in the epidemiological investigation of Klebsiella sppElevation of chemotactic factor inactivator in alcoholic liver diseaseKlebsiellaAlcohol and the Respiratory Tract7 Epidemiological Typing of Klebsiella by Bacteriocins4 Serotyping of KlebsiellaEffects of storage temperature, light and time on stability of triple sugar iron agar and its productivity forEscherichia coli andSalmonella typhimuriumEnterobacter agglomerans: a new cause of primary pneumonia.Source and extent of Klebsiella pneumoniae in the paper industryBacteriocins as tools in analysis of nosocomial Klebsiella pneumoniae infectionsKlebsiella capsular type versus site of isolation.The Gram-negative bacillary pneumoniasAn investigation into the incidence and sources of klebsiella infections in hospital patientsThe development and assessment of a bacteriocin typing method for KlebsiellaGENTAMICIN-RESISTANT KLEBSIELLA AEROGENES IN A UROLOGICAL WARDBacteriocin (klebocin) sensitivity typing of klebsiellaNationwide epidemic of septicemia caused by contaminated intravenous productsPotential Pathogens in the Environment: Cultural Reactions and Nucleic Acid Studies on Klebsiella pneumoniae from Clinical and Environmental SourcesThe classic bacterial pneumoniasCombined Biochemical and Serological Typing of Clinical Isolates of KlebsiellaOpportunistic Gram-Negative Bacillary Infections in LeukemiaSuperinfections in the Antibiotic EraPotential Pathogens in the Environment: Klebsiella pneumoniae , a Taxonomic and Ecological EnigmaPotential Pathogens in the Environment: Isolation, Enumeration, and Identification of Seven Genera of Intestinal Bacteria Associated with Small Green Pet TurtlesHospital infectionsKlebsiella type 33 septicemia in an infant intensive care unitAn Endemic Caused by Multiresistant Klebsiella in An Urological UnitMicrobiological Evaluation of Protected Environments During Patient OccupancyBacteriocine typing of Klebsiella sppIdentifying the Cause of Gastrointestinal BleedingEpidemiology of Klebsiella InfectionsSerratia marcescens as a postoperative pathogenCHANGES IN SUSCEPTIBILITY OF SELECTED PATHOGENIC BACTERIA TO WIDELY USED ANTIBIOTICSNosocomial Klebsiella Infections: Intestinal Colonization as a ReservoirRICHARD SELDEN, M.D., SHARON LEE, B.A., WEN LAN LOU WANG, PH.D., JOHN V. BENNETT, M.D., THEODORE C. EICKHOFF, M.D.KLEBSIELLA IN FÆCAL FLORA OF RENAL-TRANSPLANT PATIENTSPneumonia por bacilo de FriedlanderSerratia sp. infections in cancer patientsFour-Hour Urease Test for Distinguishing Between Klebsiella and EnterobacterBiochemical and Clinical Characteristics and Antibiotic Susceptibility of Atypical Enterobacter cloacaeUrinary Tract Infections: Correlation Between Organisms Obtained Simultaneously from the Urine and Feces of Patients with Bacteriuria and PyuriaInfektionen durch KlebsiellenBacteremias por bacilos gram-negativosACUTE BACTERIAL INFECTIONS IN THE ELDERLY MALE: CULTURES AND ANTIBIOTIC SENSITIVITY TESTSHand Lotions — A Potential Nosocomial HazardPRECIPITINS TO KLEBSIELLA AND OTHER ENTEROBACTERIA IN THE SERUM OF PATIENTS WITH CHRONIC RESPIRATORY DISORDERSIn Vitro Effectiveness of Kanamycin and Kanamycin/Cephalothin Against KlebsiellaComparison with Other AntibioticsROGER J. BULGER, M.D.The Klebsiella-Enterobacter-Serratia Division Biochemical and Serologic Characteristics and Susceptibility to AntibioticsTHEODORE C. EICKHOFF, M.D., BRUCE W. STEINHAUER, M.D., MAXWELL FINLAND, M.D., F.A.C.P. 1 December 1966Volume 65, Issue 6Page: 1180-1194KeywordsEnterobacterHospital medicineInfectious disease epidemiologyKlebsiellaKlebsiella pneumoniaeMedical servicesPneumoniaResearch laboratoriesUpper respiratory tract infectionsUrinary tract infections Issue Published: 1 December 1966 PDF DownloadLoading ...