EFFECTS OF EXCESS SODIUM CHLORIDE ON BLOOD LIPIDS: A POSSIBLE FACTOR IN CORONARY HEART DISEASE
Authors: G D TALBOTT, J R KEYS, B M KEATING, B FINKELSTEIN
Journal: Annals of Internal Medicine (1961)

Article1 February 1961EFFECTS OF EXCESS SODIUM CHLORIDE ON BLOOD LIPIDS: A POSSIBLE FACTOR IN CORONARY HEART DISEASEG. DOUGLAS TALBOTT, M.D., JOHN R. KEYS, M.D., BESSIE M. KEATING, M.T. (ASCP), BEATRICE FINKELSTEIN, M.S. (Nutrition)G. DOUGLAS TALBOTT, M.D.Search for more papers by this author, JOHN R. KEYS, M.D.Search for more papers by this author, BESSIE M. KEATING, M.T. (ASCP)Search for more papers by this author, BEATRICE FINKELSTEIN, M.S. (Nutrition)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-54-2-257 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlthough sodium chloride is an essential constituent of every living cell, in man the amount ingested appears to be dictated by conditions other than metabolic need. Diets throughout the world vary greatly in their salt content; whether or not more salt is added seems to be determined solely on the basis of palatability. Some investigators feel that palatability in turn depends chiefly upon habit,1 while others maintain that it is an inherent quality of the food itself.2-4History shows that the further a group's customs depart from the primitive, the greater is the desire for salt as a seasoning. Primitive...Bibliography1. Kaunitz H: Causes and consequences of salt consumption. Nature 178: 1141, 1956. CrossrefMedlineGoogle Scholar2. Eckel EC: Salt, Encyclopedia of the Social Sciences. Edited by E. Seligman. The Macmillan Co., New York, Vol. 13, pp. 522-526, 1955. Google Scholar3. Sherman HC: Chemistry of food and nutrition, 8th ed. The Macmillan Co., New York, pp. 232-233, 1952. Google Scholar4. Meneely GR: Salt. Amer. J. Med. 16: 1, 1954. CrossrefMedlineGoogle Scholar5. Dahl LK: Salt intake and salt need (part I). New Engl. J. 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Path. 6: 158, 1953. CrossrefMedlineGoogle Scholar13. StrausWurm RM: A new staining procedure and a method for quantitation of serum lipoproteins separated by paper electrophoresis. Tech. Bull. Regist. Med. Techn. 28: 89, 1958. MedlineGoogle Scholar14. Keating BM: The relationship of serum cholesterol to blood lipid patterns. Amer. J. Med. Techn. 23: 312-320 (Sept.-Oct.) 1957. MedlineGoogle Scholar15. Gould RG: Lipid metabolism and atherosclerosis. Amer. J. Med. 11: 209, 1951. CrossrefMedlineGoogle Scholar16. AlbrinkMan MJEB: Serum triglycerides in coronary artery disease. Arch. Intern. Med. 103: 4, 1959. CrossrefGoogle Scholar17. Bottcher CJ: Composition of lipids isolated from the aorta, coronary arteries and circulus willisii of atherosclerotic individuals. Nature 183, p. 47, 1959. CrossrefMedlineGoogle Scholar18. Bavetta L: The effect of adrenalectomy on fat absorption. Amer. J. Physiol. 134: 619, 1941. CrossrefGoogle Scholar19. MeneelyBall GRC: Experimental epidemiology of chronic sodium chloride toxicity and the protective effect of potassium chloride. Amer. J. Med. 25: 713, 1958. CrossrefMedlineGoogle Scholar20. Meneely GR: Salt. Amer. J. Med. 16: 31, 1954. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: G. DOUGLAS TALBOTT, M.D.; JOHN R. KEYS, M.D.; BESSIE M. KEATING, M.T. (ASCP); BEATRICE FINKELSTEIN, M.S. (Nutrition)Affiliations: Dayton, Ohio*Received for publication April 1, 1960.†This work was supported by Contract No. AF 33 (616)-6331, USAF.Requests for reprints should be addressed to G. Douglas Talbott, M.D., Medical Director, American Medical Research Foundation, 1230 Fidelity Medical Building, Dayton 2, Ohio. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySodium and PotassiumHyperlipoproteinemia and Inner Ear Disease 1 February 1961Volume 54, Issue 2 Page: 257-266 Keywords Blood Cholesterol Coronary heart disease Diet Eating habits Lipids Nutrition Research laboratories Salts Sodium chloride ePublished: 1 December 2008 Issue Published: 1 February 1961 PDF downloadLoading ...