LIPOID GRANULOMATOSIS (XANTHOMATOSIS) WITH MARKED PULMONARY FIBROSIS AND COR PULMONALE AS OUTSTANDING MANIFESTATIONS
Authors: S J SCHNEIERSON, L SCHNEIDER
Journal: Annals of Internal Medicine (1949)

Case Reports1 April 1949LIPOID GRANULOMATOSIS (XANTHOMATOSIS) WITH MARKED PULMONARY FIBROSIS AND COR PULMONALE AS OUTSTANDING MANIFESTATIONSSAMUEL J. SCHNEIERSON, M.D., F.A.C.P., LOUIS SCHNEIDER, M.D.SAMUEL J. SCHNEIERSON, M.D., F.A.C.P.Search for more papers by this author, LOUIS SCHNEIDER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-30-4-842 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptLargely as a result of the contributions of Hand,1Schüller,2and Christian,3"xanthomatosis" of the skeletal type became clearly established as a disease found principally in children. The clinical manifestations of the peculiar pathological process were described as defects in membranous bones, exophthalmos and diabetes insipidus, and were all attributable to "xanthomatous" involvement of membranous bones (chiefly skull) and of the hypothalamus. Since these early case reports, the same pathological process has been found in other patients, not a few of them adults. It seems obvious now that the earlier cases with skull defects, exophthalmos and diabetes insipidus represented merely...Bibliography1. HAND A: General tuberculosis, Trans. Path. Soc., Philadelphia, 1891-1893, xvi, 282-284. Google Scholar2. SCHÜLLER A: Dysostosis hypophysaria, Brit. Jr. Radiol., 1926, xxxi, 156-158. Google Scholar3. CHRISTIAN HA: Defects in membranous bones, exophthalmos and diabetes insipidus; an unusual syndrome of dyspituitarism, Med. Clin. North Am., 1920, iii, 849-871. Google Scholar4. SNAPPER I: Medical Clinics on Bone Diseases, 1943, Interscience Publishers, Inc., New York. Google Scholar5. THANNHAUSER SJ: Lipidoses: Diseases of the Cellular Lipid Metabolism, 1940, Oxford University Press, New York. Google Scholar6. CHESTERKUGEL WVH: Lipoid granulomatosis (type, Hand, Schüller-Christian), Arch. Path., 1932, xiv, 595-612. Google Scholar7. COWIEMAGEE DMMC: Lipoids and lipoid diseases, Arch. Int. Med., 1934, liii, 391-399. CrossrefGoogle Scholar8. LICHTY DE: Lipoids and lipoid diseases; xanthomatosis, Arch. Int. Med., 1934, liii, 379-390. CrossrefGoogle Scholar9. ROWLAND RS: Xanthomatosis and reticulo-endothelial system, Arch. Int. Med., 1928, xlii, 611-674. CrossrefGoogle Scholar10. SMITH LA: Xanthomatosis involving bone (lipoid histiocytosis), Radiology, 1935, xxiv, 521-534. CrossrefGoogle Scholar11. MALLORY TB: Personal communication. Google Scholar12. CURRENSPOPP JHWC: Xanthomatosis, Hand, Schüller-Christian type; report of case with pulmonary fibrosis, Am. Jr. Med. Sci., 1943, ccv, 780-785. CrossrefGoogle Scholar13. IMLER AE: Reticulo-endotheliosis with report of two cases, Am. Jr. Roentgenol. and Rad. Therap., 1946, lvi, 343-354. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Received for publication March 12, 1947.From Lebanon Hospital and The Bureau of Tuberculosis, Dept. of Health, New York City. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byRespiratory SystemHand-Schüller-Christian diseaseEOSINOPHILIC GRANULOMA OF THE LUNG*JORDAN THOMPSON, M.D., HOWARD A. BUECHNER, M.D., F.A.C.P., RONALD FISHMAN, M.D.Die angeborenen Stoffwechselanomalien des MenschenThe LipoidosesA CASE OF HAND-SCHÜLLER-CHRISTIAN SYNDROME TREATED WITH CORTISONE*WILLIAM H. BLAHD, M.D., MARVIN S. LEVY, M.D., SAMUEL H. BASSETT, M.D. 1 April 1949Volume 30, Issue 4Page: 842-851KeywordsBoneChildrenHypothalamusPulmonary fibrosisSkull ePublished: 1 December 2008 Issue Published: 1 April 1949 PDF downloadLoading ...