Chronic Epstein-Barr Virus Disease: A Workshop Held by the National Institute of Allergy and Infectious Diseases.
Authors: Martin Tobi, Stephen E. Straus
Journal: Annals of Internal Medicine (1985)

Symposium1 December 1985Chronic Epstein-Barr Virus Disease: A Workshop Held by the National Institute of Allergy and Infectious Diseases.MARTIN TOBI, M.B., Ch.B., STEPHEN E. STRAUS, M.D.MARTIN TOBI, M.B., Ch.B.Search for more papers by this author, STEPHEN E. STRAUS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-103-6-951 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptRecent studies have focused on patients with chronic fatigue accompanied by other nonspecific symptoms and elevated antibody titers to selected Epstein-Barr viral antigens, but without a clearly defined underlying disease. These patients tend to go from physician to physician in search of a diagnosis and effective treatment. The likely causes, pathophysiology, natural history, and socioeconomic implications of this syndrome are ill defined. To review the current information relating to this disorder, the National Institute of Allergy and Infectious Diseases sponsored a workshop on 22 April 1985 at the National Institutes of Health (NIH) in Bethesda, Maryland. The 50 participants represented...Symposium Papers1. PAGANO J. The biology of Epstein-Barr virus. Cancer Research Center, University of North Carolina, Chapel Hill, North Carolina. Google Scholar2. NIEDERMAN J. Epidemiology of acute infectious mononucleosis. Department of Epidemiology and Public Health, Yale University, School of Medicine, New Haven, Connecticut. Google Scholar3. HENLE W. Serological perspective—Epstein-Barr virus. Division of Virology, The Joseph Stokes, Jr., Research Institute, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania. Google Scholar4. SUMAYA C. Epstein-Barr virus serology in the field. Department of Pediatrics, Infectious Diseases, the University of Texas Health Science Center at San Antonio, San Antonio, Texas. Google Scholar5. SCHOOLEY R. Immunology of acute infectious mononucleosis. Infectious Disease Unit, Massachusetts General Hospital, Harvard School of Medicine, Boston, Massachusetts. Google Scholar6. PURTILO E. Epstein-Barr virus and immunosuppression. Department of Pathology and Laboratory Medicine, University of Nebraska Medical Center, Omaha, Nebraska. Google Scholar7. STEINBOCK M. Case history: chronic mononucleosis. Albany, New York. Google Scholar8. TOBI M. The Jerusalem, Chicago, NIH Experience. Laboratory of Tumor Immunology and Biology, National Cancer Institute, NIH, Bethesda, Maryland. Google Scholar9. DUBOIS R. The Atlanta-Arizona experience. Internal Medicine Group, Atlanta, Georgia. Google Scholar10. JONES J. Natural killer cells, lymphoblastogenesis, and in vitro interferon. Department of Pediatrics, National Jewish Hospital and Research Center, Denver, Colorado. Google Scholar11. TOSATO G. Immunological studies. Office of Biologic Research and Review, Food and Drug Administration, Bethesda, Maryland. Google Scholar12. PREBLE O. (2′-5′)-oligo-A-synthetase. Department of Pathology, Uniformed Services University of the Health Sciences, Bethesda, Maryland. Google Scholar13. LAWLEY T. Immune complexes in chronic disease. Dermatology Branch, National Cancer Institute, NIH, Bethesda, Maryland. Google Scholar14. SULLIVAN J. Treatment of Epstein-Barr virus infection. Department of Pediatrics, University of Massachusetts Medical School, Worcester, Massachusetts. Google Scholar15. OLESKE J. Treatment with gammaglobulin. Division of Allergy, Immunology and Infectious Diseases, University of Medicine and Dentistry of New Jersey, Newark, New Jersey. Google Scholar16. PARISH G. Epidemic neuromyasthenia. Myland Hospital, North Essex Health Authority, Colchester, Essex, U.K. Google Scholar17. RICHARDSON J. Multiple sclerosis and Epstein-Barr virus. Peninsula Neuropsychiatric Association, Port Angeles, Washington. Google Scholar18. MILLER G. Overview of chronic Epstein-Barr virus disease. Yale University, School of Medicine, New Haven, Connecticut. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByPathogenesis of chronic active Epstein-Barr virus infection: Is this an infectious disease, lymphoproliferative disorder, or immunodeficiency?Diseases Possibly Associated with Epstein–Barr VirusChronic fatigue syndromePsychiatric Disorders in Primary CareRecurrent Acute Disseminated Encephalomyelitis Associated With Acute Cytomegalovirus and Epstein-Barr Virus InfectionPsychische Störungen in der primärmedizinischen VersorgungSevere chronic active giftein-Barr virus infection accompanied by virus-associated hemophagocytic syndrome, cerebellar ataxia and encephalitisLatent Variable Models of Functional Somatic DistressEpstein-Barr VirusPrimary cutaneous T-cell lymphoma with an angiocentric growth pattern: association with Epstein-Barr virusIntravenous gammaglobulin: pharmacology, clinical uses and mechanisms of actionBiological response modifiers and infectious diseases: Actual and potential therapeutic agentsCytogenetic characterization of Epstein-Barr virus-associated T-cell malignanciesIncreased expression of Epstein-Barr virus in primary biliary cirrhosis patientsProtein biosynthesis and autoimmunityChronic Fatigue Syndrome: A ConundrumHistoric aspects of intravenous immunoglobulin therapyB-cell lymphoproliferative disorders after bone marrow transplant. 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PURTILO, M.D.T-Cell Lymphomas Containing Epstein–Barr Viral DNA in Patients with Chronic Epstein–Barr Virus InfectionsThe many faces of Epstein-Barr virusChronic Herpes Virus InfectionsChronic mononucleosis—a legitimate diagnosisIntravenous Immunoglobulins as Therapeutic AgentsE. RICHARD STIEHM, M.D., ELLYN ASHIDA, M.D., KWANG SIK KIM, M.D., DREW J. WINSTON, M.D., ALBERT HAAS, M.D., ROBERT P. GALE, M.D., Ph.D.Polyclonal polymorphic B-cell lymphoproliferative disorder with prominent pulmonary involvement in children with acquired immune deficiency syndromeChronic Epstein-Barr virus infections: overdiagnosed or underdiagnosed?T Cell Lymphomas in Patients with Chronic EBV InfectionEpstein-Barr Virus Infection and Hodgkin's DiseaseCORNELIUS J. DOORENBOS, M.D., JOS W.M. VAN DER MEER, M.D., D. ZANEN, M.D.Depression, Anxiety, and Epstein-Barr Virus InfectionDONNA B. GREENBERG, M.D. 1 December 1985Volume 103, Issue 6_Part_1Page: 951-953KeywordsAllergic diseasesAllergy and immunologyAntigensEpstein-Barr virusFatigueHealth information technologyInfectious diseasesViral diseasesVirology Issue Published: 1 December 1985 PDF DownloadLoading ...