THE CLINICAL EPIDEMIOLOGY OF POLIOMYELITIS
Authors: D M HORSTMANN
Journal: Annals of Internal Medicine (1955)

Article1 September 1955THE CLINICAL EPIDEMIOLOGY OF POLIOMYELITISDOROTHY M. HORSTMANN, M.D., F.A.C.P.DOROTHY M. HORSTMANN, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-43-3-526 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn this discussion of the clinical epidemiology of poliomyelitis, attention will be focused on the family epidemiology of the disease. This seems a reasonable approach, for it is the family unit with which the clinician is concerned: he is called to see a sick patient, it is true, but as with many other diseases, the circumstances under which the patient became sick are intimately connected with events involving other members of the family group.This concept is well illustrated in figure 1, which is a family chart, outlining the experience of one family infected with poliomyelitis virus, which has been...Bibliography1. HorstmannPaul DMJR: The incubation period in human poliomyelitis and its implications, J. A. M. A. 135: 11-14, 1947. CrossrefMedlineGoogle Scholar2. BrownRabsonSchieble GCASJH: The effect of gamma globulin on subclinical infection in familial associates of poliomyelitis cases. I. Quantitative estimation of fecal virus, J. Immunol. 73: 54-61, 1954. MedlineGoogle Scholar3. BrownRabsonSchieble GCASJH: The effect of gamma globulin on subclinical infection in familial associates of poliomyelitis cases. II. Serological studies and virus isolations from pharyngeal secretions, J. Immunol. 74: 71-80, 1955. MedlineGoogle Scholar4. HorstmannMcCollum DMRW: Clinical and subclinical responses to poliomyelitis infection in families, J. Clin. Investigation 33: 944, 1954. Google Scholar5. MelnickHorstmannMcCarroll JLDMJ: Unpublished observations. Google Scholar6. HorstmannMcCollumMascola DMRWAD: Viremia in human poliomyelitis, J. Exper. Med. 29: 355-369, 1954. CrossrefGoogle Scholar7. Bodian D: A reconsideration of the pathogenesis of poliomyelitis, Am. J. Hyg. 55: 414-438, 1952. MedlineGoogle Scholar8. SvedmyrEndersHolloway AJFA: Complement fixation with three types of poliomyelitis viruses propagated in tissue culture, Am. J. Hyg. 57: 60-70, 1953. MedlineGoogle Scholar9. BlackMelnick FLJL: The specificity of the complement fixation test in poliomyelitis, Yale J. Biol. and Med. 26: 385-393, 1954. MedlineGoogle Scholar10. WilmerNolanMelnick BJJL: Unpublished observations. Google Scholar11. SabinWinsser ABJ: Immunogenic effect of repeated ingestion of minute amounts of poliomyelitis virus, Federation Proc. 12: 456-457, 1953. Google Scholar12. Aycock WL: Study of the significance of geographic and seasonal variations in incidence of poliomyelitis, J. Prev. Med. 3: 245-278, 1929. Google Scholar13. Peart AF: An outbreak of poliomyelitis in Canadian Eskimoes in wintertime, Canad. J. Pub. Health 40: 405-417, 1949. MedlineGoogle Scholar14. CappsBennettStokes RRAMJ: Endemic infectious hepatitis in a children's orphanage, Arch. Int. Med. 89: 6-23, 1952. CrossrefGoogle Scholar15. Panum PL: Observations made during the epidemic of measles on the Faroe Islands in the year 1846, 1940, Delta Omega Society, New York. Google Scholar16. Horstmann DM: Poliomyelitis: severity and type of disease in different age groups, in Proceedings of Conference on the Biology of Poliomyelitis, 1955, Ann. New York Academy of Sciences, in press. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New Haven, Connecticut*From the Symposium on Preventive Medicine, presented at the Thirty-sixth Annual Session of The American College of Physicians, Philadelphia, Pennsylvania, April 29, 1955.From the Section of Preventive Medicine, Yale University School of Medicine, New Haven, Connecticut.†Aided by a grant from the National Foundation for Infantile Paralysis, Inc. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPoliomyelitis in the United States: A Historical Perspective and Current Vaccination PolicyAbortive poliomyelitis or minor illness as a clue to genetic susceptibility 1 September 1955Volume 43, Issue 3Page: 526-533KeywordsChartsClinical epidemiologyEpidemiologyExcretionInfantsMeaslesPoliomyelitisPreventive medicine ePublished: 1 December 2008 Issue Published: 1 September 1955 PDF downloadLoading ...