PARALYTIC ILEUS SIMULATING ACUTE INTESTINAL OBSTRUCTION DUE TO PENTOLINIUM TARTRATE (ANSOLYSEN)
Authors: Kenneth L. Becker, Alton I. Sutnick
Journal: Annals of Internal Medicine (1961)

Case Reports1 February 1961PARALYTIC ILEUS SIMULATING ACUTE INTESTINAL OBSTRUCTION DUE TO PENTOLINIUM TARTRATE (ANSOLYSEN)KENNETH L. BECKER, ALTON I. SUTNICKKENNETH L. BECKERSearch for more papers by this author, ALTON I. SUTNICKSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-54-2-313 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn recent years pentolinium tartrate has become one of the most widely used drugs in the treatment of severe hypertension. The case described below illustrates dramatically a side effect of this drug, ileus mimicking acute intestinal obstruction, a result of pentolinium-induced parasympatholysis.CASE REPORTThe patient was a 58-year-old white retired Army officer with known hypertension of eight years' duration. Two years prior to admission he had noticed the onset of intermittent claudication, occasional nosebleeds, dyspnea on effort, orthopnea, and occasional angina. At one time he experienced a sudden coldness of his left leg lasting several hours. He had nocturia...Bibliography1. FreisPartenopeLilienfieldRose EDEALSJC: A clinical appraisal of pentapyrrolidinium (M&B 2050) in hypertensive patients. Circulation 9: 540, (Apr.) 1954. CrossrefMedlineGoogle Scholar2. Schroeder HA: Hypertensive vascular disease: therapy with modern drugs and its limits. J. Chron. Dis. 1: 497 (May) 1955. CrossrefMedlineGoogle Scholar3. Sheldon MB: The status of present-day drug therapy of hypertension. Amer. Practit. 7: 33 (Jan.) 1956. Google Scholar4. GunnCooke JAAM: Pilocarpine as an antagonist to the undesired effects of ganglion-blocking agents in the treatment of hypertension. Brit. Med. J. 1: 1473 (June 26) 1954. CrossrefMedlineGoogle Scholar5. 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PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe radiology of drug-induced disorders in the gastrointestinal tractNeuromuscular Disease of the Gastrointestinal TractChronic Intestinal Pseudo-Obstruction SyndromesPhenothiazine effect on gastrointestinal tract functionChronic intestinal pseudoobstructionMegacolon associated with administration of an anticholinergic drug in a patient with ulcerative colitisPostoperative Intestinal Obstruction 1 February 1961Volume 54, Issue 2Page: 313-319KeywordsConstipationDiarrheaDrugsDyspneaElectrocardiographyHypertensionHypotensionIntoxicationNauseaUrea ePublished: 1 December 2008 Issue Published: 1 February 1961 PDF downloadLoading ...