THE USE OF CORTISONE AND HYDROCORTISONE IN ALLERGY
Authors: W S BURRAGE, A C RITCHIE, H C MANSMANN, J W IRWIN, A B RUSSFIELD
Journal: Annals of Internal Medicine (1955)

Article1 November 1955THE USE OF CORTISONE AND HYDROCORTISONE IN ALLERGYWALTER S. BURRAGE, M.D., F.A.C.P., A. C. RITCHIE, M.B., Ch.B., D.Phil., HERBERT C. MANSMANN JR., M.D., JOHN W. IRWIN, M.D., AGNES B. RUSSFIELD, M.D.WALTER S. BURRAGE, M.D., F.A.C.P.Search for more papers by this author, A. C. RITCHIE, M.B., Ch.B., D.Phil.Search for more papers by this author, HERBERT C. MANSMANN JR., M.D.Search for more papers by this author, JOHN W. IRWIN, M.D.Search for more papers by this author, AGNES B. RUSSFIELD, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-43-5-1001 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptINTRODUCTIONDuring the last few years compound E (cortisone) and compound F (hydrocortisone) have been used with considerable success to suppress the symptoms of allergic and related disorders. There are those who decry their use, saying that they merely suppress symptoms and that they possess potentially serious side effects. There are also those who seriously misuse these agents, employing them in trivial conditions, often in inadequate dosage and frequently with little or no supervision of the patient. The purpose of this paper is to summarize experiences with cortisone and hydrocortisone in allergic and related disorders during the last four years....Bibliography1. BurrageIrwin WSJW: The role of cortisone in the treatment of severe bronchial asthma, New England J. Med. 248: 679-682, 1953. CrossrefMedlineGoogle Scholar2. SulzbergerWittenSmith MBVHCC: Hydrocortisone (compound F) acetate ointment in dermatological therapy, J. A. M. A. 151: 468-472, 1953. MedlineGoogle Scholar3. Hill LW: Oral cortisone treatment of infantile eczema, New England J. Med. 248: 1051-1056, 1953. CrossrefMedlineGoogle Scholar4. IrwinGrahamJacobsonBurrage JWMJBMWS: Penicillin allergy, New England J. Med. 245: 246-248, 1951. CrossrefMedlineGoogle Scholar5. ShulmanSchoenrichHarvey LEEHAM: Allergic reactions to therapeutic agents: treatment with adrenocorticotropic hormone (ACTH or cortisone), Bull. Johns Hopkins Hosp. 92: 196-209, 1953. MedlineGoogle Scholar6. FriedlaenderFriedlaender SAS: Oral cortisone therapy in allergic diseases, J. Allergy 22: 291-303, 1951. CrossrefMedlineGoogle Scholar7. FeinbergDannenbergMalkiel SMTBS: ACTH and cortisone in allergic manifestations, therapeutic results and studies on immunological and tissue reactivity, J. Allergy 22: 195-210, 1951. CrossrefMedlineGoogle Scholar8. SchillerLowell IWFC: Oral cortisone in the treatment of hay fever, J. Allergy 24: 297-301, 1953. CrossrefMedlineGoogle Scholar9. Ackroyd JF: Allergic purpura, including purpura due to foods, drugs, and infections, Am. J. Med. 14: 605-632, 1953. CrossrefMedlineGoogle Scholar10. CoombsMourantRace RRAERR: A new test for the detection of weak and "incomplete" Rh agglutinins, Brit. J. Exper. Path. 26: 255-266, 1945. MedlineGoogle Scholar11. RichGregory ARJE: The experimental demonstration that periarteritis nodosa is a manifestation of hypersensitivity, Bull. Johns Hopkins Hosp. 72: 65-88, 1943. Google Scholar12. KassFinland EHM: Adrenocortical hormones in infection and immunity, Ann. Rev. Microbiol. 7: 361-388, 1953. CrossrefMedlineGoogle Scholar13. FredLevinRivoBarrett LMHJBTF: Development of active pulmonary tuberculosis during ACTH and cortisone therapy, J. A. M. A. 147: 242-246, 1951. CrossrefMedlineGoogle Scholar14. KingJohnsonBattenHenry EQJBGSWL: Tuberculosis following cortisone therapy, J. A. M. A. 147: 238-241, 1951. CrossrefMedlineGoogle Scholar15. SorsTroćme CY: Le traitement des pleürsies séro fibrineuses tuberculeuses par l'ACTH, Rev. de la tuberc. 18: 167-178, 1954. MedlineGoogle Scholar16. Cochran JB: Cortisone in treatment of pulmonary tuberculosis, Edinburgh M. J. 61: 238-249, 1954. MedlineGoogle Scholar17. BrowneAronovitchBeckLeithMeakins JSMJCWJF: The treatment of coexisting Addison's disease and active pulmonary tuberculosis, Am. J. M. Sc. 228: 491-505, 1954. CrossrefMedlineGoogle Scholar18. SauerDearingWollaeger WGWHEE: Serious untoward gastrointestinal manifestations possibly related to administration of cortisone and corticotropin, Proc. Staff Meet., Mayo Clin. 28: 641-649, 1953. MedlineGoogle Scholar19. ClarkBauerCobb LDWS: Preliminary observations on mental disturbances occurring in patients under therapy with cortisone and ACTH, New England J. Med. 246: 205-216, 1952. CrossrefMedlineGoogle Scholar20. DemartiniGrokoestRagan FAWC: Pathological fractures in patients with rheumatoid arthritis treated with cortisone, J. A. M. A. 149: 750-752, 1952. CrossrefMedlineGoogle Scholar21. Russfield AB: The endocrine glands after bilateral adrenalectomy compared with those in spontaneous adrenal insufficiency, Cancer 8: 523-537, 1955. CrossrefMedlineGoogle Scholar22. Mellgren J: The anterior pituitary in hyperfunction of the adrenal cortex; an anatomical study with special reference to Syndroma Morgagni and notes on prostatic hypertrophy, Acta path. et microbiol. Scandinav. 22 (Suppl. 60): 1-177, 1945. Google Scholar23. Pearse AG: Cytological and cytochemical investigations on the foetal and adult hypophysis in various physiological and pathological states, J. Path. and Bact. 65: 355-370, 1953. CrossrefMedlineGoogle Scholar24. Crooke AC: A change in the basophil cells of the pituitary gland common to conditions which exhibit the syndrome attributed to basophil adenoma, J. Path. and Bact. 41: 339-349, 1935. CrossrefGoogle Scholar25. Rich AR: A peculiar type of adrenal cortical damage associated with acute infections, and its possible relation to circulatory collapse, Bull. Johns Hopkins Hosp. 74: 1-15, 1944. Google Scholar26. IngramBrainCruickshankDowlingGellGoldsmithLongPercivalHellier JTRTCNGBPGWNDAGHFF: Treatment of skin disorders with ACTH and cortisone, Brit. M. J. 2: 1307-1313, 1954. MedlineGoogle Scholar27. WhortonMichaelCummingsBloom CMMMMWL: Clinicopathologic examples of untoward effects of cortisone in patients with bacterial infections, Am. J. Med. 11: 252-253, 1951 (abstract). CrossrefGoogle Scholar28. Page JA: Two cases of fulminating pneumonia in patients on hormone therapy, Brit. M. J. 2: 1334-1335, 1954. CrossrefMedlineGoogle Scholar29. ReederMackey WHGS: Nebulized cortisone in bacterial pneumonia, Dis. of Chest 18: 528-534, 1950. CrossrefMedlineGoogle Scholar30. BoyerChedid FL: La cortisone dans les infections expérimentales de la souris, Ann. Inst. Pasteur 84: 453-457, 1953. MedlineGoogle Scholar31. Editorial: Cortisone and infection, Brit. M. J. 1: 381-382, 1954. CrossrefMedlineGoogle Scholar32. KulkaPearsonRobbins JPCMSL: A distinctive vacuolar nephropathy associated with intestinal disease, Am. J. Path. 26: 349-377, 1950. MedlineGoogle Scholar33. Keye JD: Death in potassium deficiency. Report of a case including morphologic findings, Circulation 5: 766-770, 1952. CrossrefMedlineGoogle Scholar34. PerkinsPetersenRiley JGABJA: Renal and cardiac lesions in potassium deficiency due to chronic diarrhea, Am. J. Med. 8: 115-123, 1950. CrossrefMedlineGoogle Scholar35. FollisOrent-KeilesMcCollum RHEEV: The production of cardiac and renal lesions in rats by a diet extremely deficient in potassium, Am. J. Path. 18: 29-39, 1942. MedlineGoogle Scholar36. French JE: A histological study of the heart lesions in potassium-deficient rats, Arch. Path. 53: 485-496, 1952. Google Scholar37. LiebowMcFarlandTennant AAWJR: The effects of potassium deficiency on tumor-bearing mice, Yale J. Biol. and Med. 13: 523-538, 1941. MedlineGoogle Scholar38. Bennett WA: Histopathological alterations of adrenal and anterior pituitary glands in patients treated with cortisone, J. Bone and Joint Surg. 36A: 867-874, 1954. CrossrefGoogle Scholar39. WilburRich OMAR: A study of the rôle of adrenocorticotropic hormone (ACTH) in the pathogenesis of tubular degeneration of the adrenals, Bull. Johns Hopkins Hosp. 93: 321-347, 1953. MedlineGoogle Scholar40. GoldenBondySheldon APKWH: Pituitary basophile hyperplasia and Crooke's hyaline change in man after ACTH therapy, Proc. Soc. Exper. Biol. and Med. 74: 455-458, 1950. CrossrefMedlineGoogle Scholar41. O'NealHeinbecker LWP: The adenohypophysis and hypothalamus in hyperadrenalcorticalism, Ann. Surg. 141: 1-9, 1955. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Boston, Massachusetts*Presented as a Morning Lecture at the Thirty-sixth Annual Session of The American College of Physicians, Philadelphia, Pennsylvania, April 27, 1955.From the Medical Service and Department of Pathology, Massachusetts General Hospital, and the Department of Medicine, Harvard University.†Supported by a grant from the Upjohn Company and a grant from the Mary Dexter Fund. The cortisone and part of the hydrocortisone were supplied by Merck and Co., Inc., and part of the hydrocortisone by the Upjohn Company.With the technical assistance of MARY GILCHRIST and PRISCILLA GORDON. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byFatty lesions of both humeri in a patient on corticosteroids and cyclophosphamideAdrenal glucocorticoids after twenty yearsProphylaxis in patients receiving adrenal steroid therapyTHE EFFECTS OF PROLONGED CORTICOSTEROID THERAPYTHE MANAGEMENT OF ALLERGIC DISORDERS WITH ANTI-INFLAMMATORY STEROIDSThe proper use of adrenal hormonal drugs in pediatric practiceThe role of adrenocortical steroids in the treatment of intractable bronchial asthmaSteroid Hormones and the Aging SkeletonAllergy 1 November 1955Volume 43, Issue 5Page: 1001-1018KeywordsAllergy and immunologyHormonesHospital medicineMedical servicesOsteoporosisPeptic ulcersPneumoniaSpineSteroid therapyUrticaria Issue Published: 1 November 1955 PDF downloadLoading ...