SPLEEN SIZE IN PERNICIOUS ANEMIA
Authors: Edward Bigg
Journal: Annals of Internal Medicine (1940)

Article1 August 1940SPLEEN SIZE IN PERNICIOUS ANEMIAEDWARD BIGG, M.D.EDWARD BIGG, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-14-2-277 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptA palpable spleen has long been accepted as an expected finding in the physical examination of a patient suffering from pernicious anemia. Although Sturgis11 reported the spleen to be rarely palpable and Minot7 pointed out that it was palpable in only 5 per cent of his cases, the majority of standard textbooks and monographs on pernicious anemia give the incidence as from 20 to 50 per cent.Evans3reported the spleen to be palpable in 20 per cent of his cases. In McCarty's6series of 51 cases the spleen was palpably enlarged in 45 per cent. Cornell2stated that the...Bibliography1. ASKANAZY M: Die pathologische Anatomie der Anaemien, Compt. rend. d. b. Troisième Conférence Internationale de Pathologie Géographique, 1937, Helsingfors, p. 32. Google Scholar2. CORNELL BS: Pernicious anemia, 1927, Duke University Press, Durham, p. 115. Google Scholar3. EVANS FA: Pernicious anemia, 1926, Williams and Wilkins Company, Baltimore, pp. 79 and 109. Google Scholar4. KRACKEGARVER RKHE: Diseases of the blood and atlas of hematology, 1937, J. B. Lippincott, Philadelphia, p. 230. Google Scholar5. KRUMBHAARLIPPINCOTT EBSW: Postmortem weight of "normal" human spleen at different ages, Am. Jr. Med. Sci., 1939, cxcvii, 344. CrossrefGoogle Scholar6. MCCARTY WC: Chronic splenomegaly, Arch. Int. Med., 1928, xli, 536. CrossrefGoogle Scholar7. MINOTMUSSER GHJH: Internal medicine, 1938, Lea and Febiger, Philadelphia, p. 948. Google Scholar8. MEAKINS JC: The practice of medicine, 1938, C. V. Mosby, St. Louis, p. 523. Google Scholar9. ORDWAYGORHAM TLW: Diseases of the blood, Oxford monographs on diagnosis and treatment, Vol. 9, 1937, Oxford University Press, New York. Google Scholar10. STEVENS AA: The practice of medicine, 1931, W. B. Saunders, Philadelphia. Google Scholar11. STURGISMUSSER CCJH: Internal medicine, 1938, Lea and Febiger, Philadelphia, p. 948. Google Scholar12. SUAREZ RM: Clinical and hematologic review of sprue, Puerto Rico Jr. Pub. Health and Trop. Med., 1938, xiv, 157. Google Scholar13. WINTROBEMUSSER MJH: Diseases of the blood, in TICE, FREDRICK: Practice of medicine, Vol. 5, p. 841. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Chicago, Illinois*Received for publication May 29, 1939.From the Thomas Henry Simpson Memorial Institute for Medical Research, University of Michigan. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byHematological Findings in Children with Vitamin B12 DeficiencyMegaloblastic Anemia Presenting with Massive Reversible SplenomegalySevere vitamin B12 deficiency resulting in pancytopenia, splenomegaly and leukoerythroblastosis 1 August 1940Volume 14, Issue 2Page: 277-280KeywordsPernicious anemiaSpleen ePublished: 1 December 2008 Issue Published: 1 August 1940 PDF downloadLoading ...