LUPUS ERYTHEMATOSUS (ERYTHEMATODES) AND OVARIAN FUNCTION: OBSERVATIONS ON A POSSIBLE RELATIONSHIP, WITH REPORT OF SIX CASES
Authors: Edward Rose, Donald M. Pillsbury
Journal: Annals of Internal Medicine (1944)

Article1 December 1944LUPUS ERYTHEMATOSUS (ERYTHEMATODES) AND OVARIAN FUNCTION: OBSERVATIONS ON A POSSIBLE RELATIONSHIP, WITH REPORT OF SIX CASESEDWARD ROSE, M.D., F.A.C.P., DONALD M. PILLSBURY, Colonel, M.C., A.U.S.EDWARD ROSE, M.D., F.A.C.P.Search for more papers by this author, DONALD M. PILLSBURY, Colonel, M.C., A.U.S.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-21-6-1022 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe syndrome which is unfortunately known as lupus erythematosus has been the subject of an enormous literature since Hebra's clinical description, under the name of seborrhea conjestiva, in 1845. The primary etiology and pathogenesis of the disease still remain elusive despite the development of several theories.1The use of the term "lupus" was introduced in the latter part of the nineteenth century when the disease was generally considered to be tuberculous. Although opinion is still somewhat divided, a tuberculous etiology has not been established. The term "lupus," therefore, must be regarded as a misnomer, although its use has by this...Bibliography1. STOKESBEERMANINGRAHAM JHHNR: The "lupus erythematosus" concept: an attempt at integration, Am. Jr. Med. Sci., 1944, ccvii, 540. CrossrefGoogle Scholar2. JADASSOHN J: Mracek's Handbuch der Hautkrankheiten, 1904, iii, 319 (Quoted by Urbach and Thomas4). Google Scholar3. ROSEPILLSBURY EDM(a) : Acute disseminated lupus erythematosus—a systemic disease, Ann. Int. Med., 1939, xii, 951. (b) REIFENSTEIN, E. C., REIFENSTEIN, E. C., JR., and REIFENSTEIN, G. H.: A variable symptom complex of undetermined etiology with fatal termination, including conditions described as visceral erythema group (Osler), disseminated lupus erythematosus, atypical verrucous endocarditis (Libman-Sachs), fever of unknown origin (Christian), and diffuse peripheral vascular disease (Baehr and others), Arch. Int. Med., 1939, lxiii, 553. (c) BANKS, B. M.: Is there a common denominator in scleroderma, dermatomyositis, disseminated lupus erythematosus, Libman-Sachs syndrome and polyarteritis nodosa? New England Jr. Med., 1941, ccxxv, 433. Google Scholar4. URBACHTHOMAS ECC: Classification and definition of the clinical varieties of erythematodes (lupus erythematosus) with particular reference to its acute and subacute course, Brit. Jr. Dermat., 1939, li, 343. CrossrefGoogle Scholar5. O'LEARY PA: Symposium on lupus erythematosus, Proc. Staff Meet. Mayo Clin., 1940, xv, 686. Google Scholar6. KRUPP MA: Urinary sediment in visceral angiitis (periarteritis nodosa, lupus erythematosus, Libman-Sachs "disease"); quantitative studies, Arch. Int. Med., 1943, lxxi, 54. CrossrefGoogle Scholar7. KEITH NM: Symposium on lupus erythematosus, Proc. Staff Meet. Mayo Clin., 1940, xv, 682. Google Scholar8. GROSSFRIEDBERG LCK: Nonbacterial thrombotic endocarditis, classification and general description, Arch. Int. Med., 1936, lviii, 620. CrossrefGoogle Scholar9. LIBMANSACHS EB: A hitherto undescribed form of valvular and mural endocarditis, Trans. Assoc. Am. Phys., 1923, xxxviii, 46. Google Scholar10. MONTGOMERY H: Symposium on lupus erythematosus, Proc. Staff Meet. Mayo Clin., 1940, xv, 678. Google Scholar11. KLEMPERERPOLLACKBAEHR PADG: Diffuse collagen disease; acute disseminated lupus erythematosus and diffuse scleroderma, Jr. Am. Med Assoc., 1942, cxix, 331. CrossrefGoogle Scholar12. URBACH E: Schwerste Lichtdermatosen auf Grundlage von isolierter pathologischer Porphyrinbildung im Darme infolge Dysbakterie und Hepatopathie, Klin. Wchnschr., 1938, xvii, 304-310. CrossrefGoogle Scholar13. MATTRAS A: Zur Symtomatologie und Klinik tödlich verlaufender Fälle von Lupus erythematosus, Arch. f. Dermat. u. Syph., 1938, clxxvii, 223. CrossrefGoogle Scholar14. BAEHR G: In Text Book of Medicine by R. S. CECIL, 1943, W. L. Saunders, Philadelphia and London, p. 461. Google Scholar15. CONTRATTOLEVENE AWSA: Acute lupus erythematosus disseminatus; report of case, New England Jr., Med., 1939, ccxxi, 602. CrossrefGoogle Scholar16. SOSMAN M: Personal Communication. Google Scholar17. CLUXTONKRAUSE HELA: Acute lupus erythematosus disseminatus; Ann. Int. Med., 1943, xix, 843. Google Scholar18. SELYE H: Production of nephrosclerosis by overdosage with desoxycorticosterone acetate, Canad. Med. Assoc. Jr., 1942, xlvii, 515. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Philadelphia, Pennsylvania*Received for publication July 20, 1944.From the Endocrine Section of the Medical Clinic and the Department of Cutaneous Medicine, Hospital of the University of Pennsylvania.Colonel Pillsbury's contribution to this communication preceded his entry into the Army of the United States. 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Implications for immunity?The effects of hormonal and other stimuli on cell-surface Ro/SSA antigen expression by human keratinocytes in vitro: their possible role in the induction of cutaneous lupus lesionsAutoimmunity and the ovarySex hormone modulation in systemic lupus erythematosus: still a therapeutic option?Anti-Estrogen Antibodies in Systemic Lupus Erythematosus: A Quantitative Evaluation of Serum LevelsEffects of gender and sex steroids on the immune responseEstrogen exaggerates lupus but suppresses T-cell-dependent autoimmune diseaseMale lupus: Retrospective analysis of the clinical and laboratory features of 52 patients, with a review of the literatureSex Hormones and Autoimmune Rheumatic DisordersSystemic lupus erythematosus and human developmentNon-enzymatic modification of proteins by steroids: Pathological implications for autoimmunity and glucocorticoid toxicitySex steroids and the rheumatic diseasesRole of Sex Steroids in Systemic Lupus Erythematosus (SLE)Familial systemic lupus erythematosus in malesSex Hormones and Modulation of Immune Response in SLESex effects in systemic lupus erythematosus. a clue to pathogenesisRegulation of the Expression of Autoimmunity in NZB x NZW F 1 Mice by Sex HormonesPathogenic Mechanisms of Drug-Induced PhotosensitivityREFERENCESLupus ErythematosusDie SexualhormoneFamilial Occurrence of Disseminated Lupus ErythematosusGeneral Practice ReviewRECURRENT ACUTE LUPUS ERYTHEMATOSUS DISSEMINATUS: REPORT OF A CASE WHICH HAS SURVIVED TWENTY-THREE YEARS AFTER THE ONSET OF SYSTEMIC MANIFESTATIONS*SOLOMON BEN-ASHER, M.D.A Clinical and Pathologic Study of Disseminated Lupus ErythematosusSubacute and Acute Disseminated Lupus ErythematodesThe Use of Androgens in Women 1 December 1944Volume 21, Issue 6Page: 1022-1034KeywordsEstrogensEtiologyGonadotropinsHospital medicineLupus erythematosusPathogenesis ePublished: 1 December 2008 Issue Published: 1 December 1944 PDF downloadLoading ...