MENINGITIS DUE TO PSEUDOMONAS PYOCYANEA: A REPORT OF THREE CASES TREATED SUCCESSFULLY WITH STREPTOMYCIN AND SULFADIAZINE
Authors: L WEINSTEIN, T S PERRIN
Journal: Annals of Internal Medicine (1948)

Article1 July 1948MENINGITIS DUE TO PSEUDOMONAS PYOCYANEA: A REPORT OF THREE CASES TREATED SUCCESSFULLY WITH STREPTOMYCIN AND SULFADIAZINELOUIS WEINSTEIN, THOMAS S. PERRINLOUIS WEINSTEINSearch for more papers by this author, THOMAS S. PERRINSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-29-1-103 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptInfections of the meninges withPseudomonas pyocyanea(Pseudomonas aeruginosa) are distinctly uncommon but cannot be dismissed as unimportant because they have a high mortality rate, and constitute a serious risk in any procedure involving penetration of the membranes surrounding the brain or spinal cord. Stanley,1in a recent review of the literature, collected 41 cases of primaryPs. pyocyaneameningitis and 28 additional instances in which this disease appeared to be secondary to a focus elsewhere. To the latter type he added one case of his own. Of the group of primary meningitides, 78 per cent occurred as a result...Bibliography1. STANLEY MM: Bacillus pyocyaneus infections. A review, report of cases and discussion of newer therapy including streptomycin, Am. Jr. Med., 1947, ii, 253-277, 347-367. CrossrefGoogle Scholar2. HARRISBUXBAUMAPPELBAUM RCLE: Secondary Bacillus pyocyaneus infection in meningitis following intrathecal penicillin therapy, Jr. Lab. and Clin. Med., 1946, xxxi, 1113-1120. Google Scholar3. CAIRNSDUTHIESMITH MESHV: Intrathecal streptomycin in meningitis. Clinical trial in tuberculous, coliform and other infections, Lancet, 1946, ii, 153-155. CrossrefGoogle Scholar4. MERWARTHROSENBERGPULITO HRHF: Pyocyaneus meningitis followed by unusual complications attributed to treatment with streptomycin, Brooklyn Hosp. Jr., 1947, v, 93-96. Google Scholar5. PAINEMURRAYHARRISFINLAND TFRHWM: Streptomycin in the treatment of certain gram-negative bacillus infections of the central nervous system, Am. Jr. Med. Sci., 1947, ccxiii, 676-685. CrossrefGoogle Scholar6. PAINEFINLAND TBM: The use of streptomycin in the treatment of meningitis, Med. Clin. North Am., Boston Number, 1947, 1092-1105. CrossrefMedlineGoogle Scholar7. DEBAKEYPULASKI MEEJ: An analysis of the experience with streptomycin in United States Army hospitals. Preliminary report, Surgery, 1946, xx, 749-760. Google Scholar8. MURRAYPAINEFINLAND RTFM: Streptomycin. I. Bacteriological and pharmacological aspects, New England Jr. Med., 1947, ccxxxvi, 701-712. PAINE T. F. MURRAY R. FINLAND M.: Streptomycin. II. Clinical uses, Ibid., 1947, ccxxxvi, 748-760. CrossrefGoogle Scholar9. MURRAYKILHAMWILCOXFINLAND RLCM: Development of streptomycin resistance of gram negative bacilli in vitro and during treatment, Proc. Soc. Exper. Biol. and Med., 1946, lxiii, 470-474. CrossrefGoogle Scholar10. RUTSTEINSTEBBINSCATHCARTHARVEY DRRR: The absorption and excretion of streptomycin in human chronic typhoid carriers, Jr. Clin. Invest., 1945, xxiv, 898-909. CrossrefGoogle Scholar11. MOLITORGRAESSLEKUNAMUSHETTSILBER HOSCR: Some toxicological and pharmacological properties of streptomycin, Jr. Pharmacol. and Exper. Therap., 1946, lxxxvi, 151-173. Google Scholar12. MADIGANSWIFTBROWNLEE DGPNG: Clinical and pharmacologic aspects of toxicity of streptomycin, Lancet, 1947, i, 9-11. CrossrefGoogle Scholar13. Streptomycin in treatment of infections: Report of one thousand cases, Jr. Am. Med. Assoc., 1946, cxxxii, 4-11, 70-76. Google Scholar14. KOSKE F: Der Bacillus pyocyaneus als Erreger einer Rhinitis und Meningitis Hemorrhagica bei Schweinen, Arb. a. d. k. Gsndhtamte., Berlin, 1906, xxxiii, 542-553. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Boston, Massachusetts*Received for publication November 4, 1947.From the Haynes Memorial and Evans Memorial, Massachusetts Memorial Hospitals and the Department of Medicine, Boston University School of Medicine, Boston, Mass. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byIntraventricular or intrathecal use of polymyxins in patients with Gram-negative meningitis: a systematic review of the available evidencePosttraumatic MeningitisPseudomonas septicemiaPyocyaneus-Sepsis im Neugeborenenalter bei GeschwisternPSEUDOMONAS AERUGINOSA MENINGITIS FOLLOWING SPINAL ANESTHESIA: REPORT OF TWO SUCCESSFULLY TREATED CASES*BERNARD H. PASTOR, M.D., WILLIAM I. GEFTER, M.D., F.A.C.P., SAMUEL BAER, M.D., F.A.C.P. 1 July 1948Volume 29, Issue 1Page: 103-117KeywordsBrainDeath ratesHospital medicineMeningesMeningitisPseudomonas aeruginosaPseudomonas infectionsSpinal cordStreptomycin ePublished: 1 December 2008 Issue Published: 1 July 1948 PDF downloadLoading ...