A DISCUSSION OF THE CONCEPT OF CARDIAC FAILURE IN THE LIGHT OF RECENT PHYSIOLOGIC STUDIES IN MAN
Authors: A COURNAND
Journal: Annals of Internal Medicine (1952)

Article1 October 1952A DISCUSSION OF THE CONCEPT OF CARDIAC FAILURE IN THE LIGHT OF RECENT PHYSIOLOGIC STUDIES IN MANANDRÉ COURNANDANDRÉ COURNANDAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-37-4-649 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn any line of scientific investigation it is profitable to pause from time to time to reëxamine concepts in the light of new experience. Quoting J. B. Conant1 freely, the value and significance of a conceptual scheme in science are not so much that it constitutes "a quest for certainty," but rather that it "breeds new experiments which in time generate new ideas." The fruitfulness of such an intellectual endeavor in medicine is, in addition, measured by its consequences in terms of the practical applications to which it leads, among which progress in therapy stands foremost.In the last 10...Bibliography1. 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McMichaelSharpey-Schafer JEP: The action of intravenous digoxin in man, Quart. J. Med. 13: 123, 1944. Google Scholar24. McMichael J: Pharmacology of the failing human heart, monograph, 1950, Charles C Thomas, Springfield. Google Scholar25. HarveyFerrerRichardsCournand RMMIDWA: Influence of chronic pulmonary disease on the heart and circulation, Am. J. Med. 10: 719, 1951. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: ANDRÉ COURNANDAffiliations: New York, N. Y.*Presented as the John Phillips Memorial Lecture at the Thirty-third Annual Session of the American College of Physicians, Cleveland, Ohio, April 23, 1952.From the Department of Medicine, Columbia University, College of Physicians and Surgeons, and the Cardio-Pulmonary Laboratory of the First Medical and Chest Services (Columbia University Division), Bellevue Hospital, New York, N. Y.The work reported here was aided by a research grant (PHS Grant H-833 (C)) from the National Heart Institute of the National Institutes of Health, Public Health Service, with additional support from the Life Insurance Medical Research Fund. Nextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAndré Cournand, Bellevue's Cardiopulmonary Laboratory, and Research on Heart FailureRight Ventricular PhysiologySkeletal Muscle Metabolism in Heart FailureHerzveränderungen bei arterieller HypertonieShock following acute myocardial infarction current understanding of hemodynamic mechanismsHerzvolumen und DruckbelastungErgebnisse einer neuen Methode zur Registrierung des zentralen VenendrucksDer Füllungsdruck des HerzensDRUGS WITH PREDOMINANTLY CARDIAC ACTIONDer Druckablauf im rechten Vorhof des menschlichen Herzens und seine Beziehung zur HerzdynamikBeitrag der Klinik zur Dynamik des HerzensPrimary Myocardial Disease Part II. Hemodynamic AlterationsCLOYD L. 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