NITROGEN METABOLISM IN CHRONIC IDIOPATHIC ULCERATIVE COLITIS AND ITS THERAPEUTIC SIGNIFICANCE
Authors: T S SAPPINGTON, H L BOCKUS
Journal: Annals of Internal Medicine (1949)

Article1 August 1949NITROGEN METABOLISM IN CHRONIC IDIOPATHIC ULCERATIVE COLITIS AND ITS THERAPEUTIC SIGNIFICANCETHOMAS S. SAPPINGTON, M.D., HENRY L. BOCKUS, M.D., F.A.C.P.THOMAS S. SAPPINGTON, M.D.Search for more papers by this author, HENRY L. BOCKUS, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-31-2-282 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptINTRODUCTIONWe have undertaken a preliminary study of the protein requirement of patients suffering from chronic idiopathic ulcerative colitis. The problem has been approached by means of the familiar nitrogen balance determination together with measuiement of the serum proteins, blood urea, red blood cell count and hematocrit. Blood volume studies could not be made. No attempt has been made to consider the question of protein metabolism in detail, but rather we have confined our interest to the over-all exchange of nitrogen.Recently, the importance of high protein diets in treatment of a host of diseases has been emphasized. The benefit...Bibliography1. MADDENBASSETTREMINGTONMARTINWOODSSHULL SCSHJHFJRRFW: Amino acids in therapy of disease, Surg., Gynec. and Obst., 1946, lxxxii, 131. Google Scholar2. REMINGTONLUNDYBARGEN JHJSJA: Amino acid alimentation in gastrointestinal diseases, Gastroenterology, 1946, vii, 442. Google Scholar3. PAULSON M: Discussion of article by Remington, et al., Gastroenterology, 1946, vii, 448. Google Scholar4. MACHELLAMILLER TETG: Treatment of idiopathic ulcerative colitis by means of a "medical ileostomy" and an orally administered protein hydrolysate-dextri-maltose mixture, Gastroenterology, 1948, x, 28. Google Scholar5. GROSSMANSAPPINGTONBURROWSLAVIETESPETERS CMTSBAPHJP: Nitrogen metabolism in acute infections, Jr. Clin. Invest., 1945, xxiv, 523. CrossrefGoogle Scholar6. BOSTBORGSTROM RWP: Cutaneous excretions of nitrogenous material in New Orleans, Am. Jr. Physiol., 1926-27, lxxix, 242. CrossrefGoogle Scholar7. CUTHRERTSONMCCUTCHEONMUNRO DPAHN: A study of the effect of overfeeding on the protein metabolism of man. I. The effect of superimposing raw and boiled milks on a diet adequate for maintenance, Biochem. Jr., 1937, xxxi, 681. II. The superimposition on a diet adequate for maintenance, of beef (or soya flour) and lactose and butter, equivalent in protein, carbohydrate and fat content to a litre of milk, Ibid., 689. CrossrefGoogle Scholar8. PETERSVAN SLYKE JPDD: Quantitative clinical chemistry. Interpretations. Vol. I. Second edition, 1946, Williams and Wilkins Co., Baltimore, Md., p. 659. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication March 25, 1948.From the Gastrointestinal Service of the Graduate Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.Aided by a grant from the Julia Keim Memorial Fund.†American College of Physicians Research Fellow in Internal Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe History of Medical Therapy of Ulcerative ColitisUlcerative ColitisColitis ulcerosaThe Management of Ulcerative ColitisDie Colitis UlcerosaUlcerative ColitisNITROGEN BALANCE STUDIES IN LAENNEC'S CIRRHOSIS OF THE LIVER*WALTER R. COOK, HOWARD A. VAN AUKENThe Relation of Protein Metabolism to DiseaseMetabolic Derangements in Chronic Ulcerative Colitis 1 August 1949Volume 31, Issue 2Page: 282-302KeywordsDietGraduate medical educationHematocritNitrogen metabolismProtein metabolismProteinsRed blood cellsSerum proteinsUlcerative colitisUrea ePublished: 1 December 2008 Issue Published: 1 August 1949 PDF downloadLoading ...