LIVER DYSFUNCTION HYPERGLYCEMIA: ITS ETIOLOGY AND RELATION TO DIABETES MELLITUS
Authors: Samuel J. Taub, William H. Shlaes, Lester Rice
Journal: Annals of Internal Medicine (1945)

Article1 June 1945LIVER DYSFUNCTION HYPERGLYCEMIA: ITS ETIOLOGY AND RELATION TO DIABETES MELLITUSSAMUEL J. TAUB, M.D., WILLIAM H. SHLAES, M.D., LESTER RICE, M.S., PH.D.SAMUEL J. TAUB, M.D.Search for more papers by this author, WILLIAM H. SHLAES, M.D.Search for more papers by this author, LESTER RICE, M.S., PH.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-22-6-852 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptRecent work has shown that numerous conditions other than diabetes mellitus are accompanied by hyperglycemia; the more significant of these conditions include obesity, liver damage, and hyperpituitarism. That this symptom appears in such diverse diseases is explicable by the fact that control of the blood sugar is determined not only by the level of insulin in the blood but by the state of the liver, kidneys and gastrointestinal tract as well as by the level of the pituitary-adrenal hormones.OBSERVATIONSWhile engaged in testing a modified insulin preparation in a series of diabetic patients, the authors felt obliged to ascertain...Bibliography1. MICKS RH: Diet in diabetes, Brit. Med. Jr., 1943, i, 598-600. CrossrefGoogle Scholar2. NEWBURGH LH: The control of hyperglycemia of obese "diabetics" by weight reduction, Ann. Int. Med., 1942, xvii, 935-942. Google Scholar3. STROUSEROSENBAUMLEVYSOSKIN CDEERCS: Intensive carbohydrate therapy in diabetic patients with manifest or suspected liver disease, Jr. Clin. Endocrinol., 1941, i, 831-835. CrossrefGoogle Scholar4. REGANWESTRAWILDER JFJJRM: Insulin resistance; report of a case, New England Jr. Med., 1940, ccxxiii, 745-750. CrossrefGoogle Scholar5. HARTLISA JFJR: Cirrhosis arrested in a diabetic following insulin therapy; report of a case, New York State Jr. Med., 1938, xxxviii, 1158-1161. Google Scholar6. KOHN LW: Is diabetes due to diseases in the liver? New York State Jr. Med., 1926, xxvi, 182-184. Google Scholar7. RABINOWITCH IM: Note on the bilirubin content of blood and the urobilinogen content of urine in diabetes mellitus, Brit. Jr. Exper. Path., 1936, xvii, 249-251. Google Scholar8. SOMOGYI M: Blood diastase in health and diabetes, Jr. Biol. Chem., 1940, cxxxiv, 315-318. CrossrefGoogle Scholar9. BATTYGRAY JLS: Involvement of the liver in disease of the gall bladder, Arch. Int. Med., 1943, lxxii, 176-184. CrossrefGoogle Scholar10. SOSKIN S: Endocrine disturbances in the regulation of the blood sugar, Clinics, 1943, i, 1286-1309. Google Scholar11. UNGER H: Diabetes und Hepatitis, Ztschr. f. klin. Med., 1934, cxxvii, 166-171. Google Scholar12. BOYD W: Pathology of internal diseases, 3rd ed., 1940, Lea and Febiger, Philadelphia. Google Scholar13. Symposium on respiratory enzymes, 1942, U. of Wisconsin Press, Madison. Google Scholar14. MIRSKYNELSONELGARTGRAYMAN IANSI: Production of permanent hyperglycemia and glycosuria by the prolonged administration of insulin, Science, 1942, xcv, 583-584. CrossrefGoogle Scholar15. SOSKIN S: The blood sugar: its origin, regulation and utilization, Physiol. Rev., 1941, xxi, 140-193. CrossrefGoogle Scholar16. ROSENBAUMDE KRUIFLAVIETES JDHPH: The effect of insulin on the glucose tolerance of normal man, Jr. Clin. Invest., 1944, xxiii, 45-50. CrossrefGoogle Scholar17. WILDERSMITHSANDIFORD RMFHI: Observations on obesity, Ann. Int. Med., 1932, vi, 724-742. LinkGoogle Scholar18. MAHERSOMOGYI JTM: The effect of insulin on the carbohydrate tolerance of non-diabetic individuals, Proc. Soc. Exper. Biol. and Med., 1938, xxxvii, 615-618. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Chicago, Illinois*Received for publication September 18, 1944.From the medical service of Dr. Samuel J. Taub, Ward 55, Cook County Hospital. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byTHE ETIOLOGY OF DIABETES MELLITUS IN MANAN AUTOPSY CASE OF STUNTED GROWTH WITH FATTY LIVER CIRRHOSIS, HEPATOMA, HYPOGONADISM, OSTEOPOROSIS AND LIPID PNEUMONIAClinical Studies in Chronic Alcoholism I.REFERENCESDiabetes Mellitus and Liver FunctionSerum Phosphorus and Potassium Levels after Intravenous Administration of GlucoseOral Glucose Tolerance as a Test of Liver FunctionA clinical study of the pathogenesis of the diabetic syndrome: Use of a modified glucose insulin tolerance test combined with the change of serum inorganic phosphorus after glucose administrationInfection of the gall bladder and diabetesTurbidimetric Studies of Serum Colloids in Diabetes MellitusDiabetes mellitus and liver dysfunctionNutritional Therapy of Endocrine Disturbances 1 June 1945Volume 22, Issue 6Page: 852-862KeywordsDiabetes mellitusGratitudeHyperglycemiaInsulinKidneysLiverLiver diseasesMedical servicesObesityProlactin Issue Published: 1 June 1945 PDF downloadLoading ...