OSTEO-NEPHROPATHY: A CLINICAL CONSIDERATION OF "RENAL RICKETS"
Authors: Colter Rule, Arthur Grollman
Journal: Annals of Internal Medicine (1944)

Article1 January 1944OSTEO-NEPHROPATHY: A CLINICAL CONSIDERATION OF "RENAL RICKETS"COLTER RULE, M.D., ARTHUR GROLLMAN, PH.D., M.D., F.A.C.P.COLTER RULE, M.D.Search for more papers by this author, ARTHUR GROLLMAN, PH.D., M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-20-1-63 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe association of bone changes and renal disease has long been recognized,1and for some years these associated phenomena have been designated as "renal rickets." Within the past decade, however, the plurality of the underlying disorders responsible for this clinical syndrome has been established. There is evidence that some patients suffering from the condition may be dramatically improved with appropriate therapy,2whereas treatment of the more outstanding manifestations of the disease may be followed by aggravation of the symptoms. An attempt to set up criteria for the differentiation of the various forms of the disorder is therefore indicated. Two cases...Bibliography1. GROLLMAN A: Chapter on "Dwarfism," Oxford Medicine, edited by H. CHRISTIAN, 1942, Oxford University Press, New York. Google Scholar2. ALBRIGHTCONSOLAZIOCOMBSSULKOWITCHTALBOTT FWVFSHWJH: Metabolic studies and therapy in a case of nephrocalcinosis with rickets and dwarfism, Bull. Johns Hopkins Hosp., 1940, lxvi, 7. Google Scholar3. PARSONS LG: Bone changes occurring in renal and coeliac infantilism, and their relationship to rickets; renal rickets, Arch. Dis. Child., 1927, ii, 1. CrossrefGoogle Scholar4. 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Child., 1939, lviii, 540. CrossrefGoogle Scholar19. AUB JC: Lack of effect of parathyroid glands on growth of bone, Endocrinology, 1942, xxx, 1024. Google Scholar20. LIGNAC GO: Syndrome consisting of affections of the kidney, stunted growth, rickets and disturbed cystine metabolism, Am. Jr. Med. Sci., 1938, cxcvi, 542. CrossrefGoogle Scholar21. HAMILTONDEWAR BMM: The effect of citrate and tartrate on experimental rickets, Am. Jr. Dis. Child., 1937, liv, 548. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Winston-Salem, North Carolina*Received for publication September 21, 1942.From the Department of Internal Medicine, The Bowman Gray School of Medicine of Wake Forest College, and the North Carolina Baptist Hospital, Winston-Salem, N. C.This study was aided by a grant from the Dazian Foundation, New York. 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