ACUTE MENINGOCOCCEMIA WITH SYMMETRIC PERIPHERAL GANGRENE: REPORT OF A CASE WITH RECOVERY
Authors: V K PHILIPS
Journal: Annals of Internal Medicine (1958)

Case Reports1 April 1958ACUTE MENINGOCOCCEMIA WITH SYMMETRIC PERIPHERAL GANGRENE: REPORT OF A CASE WITH RECOVERYVOL K. PHILIPS, M.D.VOL K. PHILIPS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-48-4-864 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe patient with acute meningococcemia and rapidly falling blood pressure presents one of the most dramatic medical emergencies physicians encounter. In nonepidemic areas or seasons the occasional case is likely to escape recognition until the typical purpura, disorientation and peripheral vascular collapse alert the physician to the septicemic nature of the disease. With the advent of oral and parenteral steroid therapy, death from meningococcemia, with or without severe hypotension, is now the exemption rather than the rule.1-7That recovery can be obtained in even the most severely ill is illustrated by the following case which, in addition to the usual...Bibliography1. NelsonGoldstein JN: The nature of the Waterhouse-Friderichsen syndrome, J. A. M. A. 146: 1193-1197, 1951. CrossrefMedlineGoogle Scholar2. WheelerAmidon DEI: Waterhouse-Friderichsen syndrome, New England J. Med. 247: 256-258, 1952. CrossrefMedlineGoogle Scholar3. BreenEdmondWalley GERTRV: The Waterhouse-Friderichsen syndrome treated with cortisone, Lancet 1: 1140-1142 (June 7) 1952. CrossrefMedlineGoogle Scholar4. Uhl HS: Nor-epinephrine in the treatment of acute meningococcemia with shock (Waterhouse-Friderichsen syndrome) and an evaluation of adrenocortical function, New England J. Med. 249: 229, 1953. CrossrefMedlineGoogle Scholar5. HodesMoloshokMarkowitz HLREM: Fulminating menincococcemia treated with cortisone: use of blood eosinophil count as a guide to prognosis and treatment, Pediatrics 10: 138, 1952. MedlineGoogle Scholar6. GriffinDaeschnor JWCW: Meningococcal infections: with particular reference to fulminating meningococcemia (Waterhouse-Friderichsen syndrome) treated with cortisone and nor-epinephrine, J. Pediat. 45: 264, 1954. CrossrefMedlineGoogle Scholar7. Tobin JL: Complications of meningococcal infection in a series of sixty-three consecutive sporadic cases, Am. J. M. Sc. 231: 241, 1956. CrossrefMedlineGoogle Scholar8. McCrumbHallMeredithDeaneMinorWoodward FRHEAMGEJVTE: Chloramphenicol in the treatment of meningococcal meningitis, Am. J. Med. 10: 696, 1951. CrossrefMedlineGoogle Scholar9. Etteldorf JN: Management of purulent meningitis, J. A. M. A. 159: 746, 1955. CrossrefMedlineGoogle Scholar10. Alexander HE: Guides to optimal therapy in bacterial meningitis, J. A. M. A. 152: 662, 1953. CrossrefMedlineGoogle Scholar11. Fishberg AM: Redistribution of blood in heart failure, J. Clin. Investigation 17: 510, 1938. Google Scholar12. Storstein O: Incipient symmetrical peripheral gangrene complicating pneumonia, Brit. Heart J. 13: 411, 1951. CrossrefMedlineGoogle Scholar13. SwanHenderson WGCB: Peripheral gangrene in myocardial infarction, Brit. Heart J. 13: 68, 1951. CrossrefMedlineGoogle Scholar14. BirdLeitheadLowe TCSKG: Symmetrical peripheral gangrene in low-output heart failure, Lancet 2: 780, 1954. CrossrefGoogle Scholar15. CaserteMetzAnton SJRM: Symmetrical peripheral gangrene in myocardial infarction, New England J. Med. 254: 568, 1956. CrossrefMedlineGoogle Scholar16. Boyd W: A textbook of pathology, 1953, Lea and Febiger, Philadelphia. Google Scholar17. Woodward TE: Clues to better understanding of the nature and treatment of certain infectious diseases, Am. J. M. Sc. 231: 369, 1956. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Columbus, Ohio*Received for publication July 23, 1956.From The Columbus Medical Center, Columbus, Ohio.Requests for reprints should be addressed to Vol K. Philips, M.D., The Columbus Medical Center, 1211 Dublin Road, Columbus 8, Ohio. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDurch Gram-negative Bakterien bedingte Hauterscheinungen bei septischen KrankheitenThrombocytopenia and Symmetrical Peripheral Gangrene Associated with Staphylococcal and Streptococcal BacteremiaJAMES J. RAHAL JR., M.D., H. EDWARD MACMAHON, M.D., LOUIS WEINSTEIN, PH.D., M.D., F.A.C.P.SYMMETRIC PERIPHERAL GANGRENE IN PNEUMOCOCCAL SEPSIS*RICHARD E. BETTIGOLE, M.D. 1 April 1958Volume 48, Issue 4Page: 864-871KeywordsBlood pressureBradycardiaHypotensionMeningococcemiaNeisseria meningitidisPeripheral vascular diseaseSteroid therapyVascular diseases Issue Published: 1 April 1958 PDF downloadLoading ...