THE AZORUBIN S TEST OF LIVER FUNCTION; AN EVALUATION, WITH A COMPARATIVE STUDY OF THE BROMSULPHALEIN AND HIPPURIC ACID TESTS
Authors: David H. Rosenberg, Samuel Soskin
Journal: Annals of Internal Medicine (1940)

Article1 March 1940THE AZORUBIN S TEST OF LIVER FUNCTION; AN EVALUATION, WITH A COMPARATIVE STUDY OF THE BROMSULPHALEIN AND HIPPURIC ACID TESTSDAVID H. ROSENBERG, M.D., SAMUEL SOSKIN, M.D.DAVID H. ROSENBERG, M.D.Search for more papers by this author, SAMUEL SOSKIN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-13-9-1644 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptFew tests of liver function have proved to be of much value in the diagnosis and prognosis of diseases of this organ. Common to all is the failure to detect hepatic disease in its earlier stages. The multiplicity of the liver's functions, as well as its great regenerative capacity and functional reserve, provides ample explanation for this shortcoming. Although a better understanding of the condition of the liver may be derived from a combined study of several hepatic functions, any test which might elicit more trustworthy information concerning a single function deserves further investigation.Azorubin S,† a dark red, stable,...References1. BLOCHROSENBERG LDH: Unpublished. Google Scholar2. EPPINGER H: Die Leberkrankheiten. Allgemeine und spezielle Pathologie und Therapie der Leber, Wien. Verlag von Julius Springer, 1937, pp. 179-180. Google Scholar3. FENSTERMANN R: Die Funktionsprüfung der Leber mit Azorubin S, München. med. Wchnschr., 1926, lxxiii, 859. Google Scholar4. KOHLSTAEDTHELMER KGOM: A study of the hippuric acid excretion as a test of hepatic function, Am. Jr. Digest. Dis. and Nutr., 1936, iii, 459. CrossrefGoogle Scholar5. LEBEDOW AJ: Die Chromocholoskopische Azorubinprobe, Arch. f. Verdauungskr., 1930, xlvii, 131. CrossrefGoogle Scholar6. 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ZINNY M: El estudio de la función hepática, en especial por la azorrubina, Prensa méd. Argentina, 1926, xiii, 665. Azorrubina en la función hepática, Ibid., 1927, xiv, 402. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Chicago, Illinois*Received for publication December 10, 1938.From the Department of Medicine and the Department of Metabolism and Endocrinology, Michael Reese Hospital, and from the Department of Medicine, Northwestern University School of Medicine.†The Azorubin S solution used in this study was prepared by George A. Breon & Co., Kansas City, Missouri. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe Clinical Chemistry of Bromsulfophthalein and Other Cholephilic DyesLiver Function Tests in Rheumatoid ArthritisPhysiologische Chemie einzelner Lebensvorgänge und Organe (Fortsetzung)Intravital staining of damaged liver cells II. The use of dyes in the study of necrosis and repair following acute chemical injuryThe significance of dosage and time factors on the value of the bromsulphthalein test for liver function 1 March 1940Volume 13, Issue 9Page: 1644-1654KeywordsEndocrinologyHospital medicineLiverLiver diseasesLiver function tests ePublished: 1 December 2008 Issue Published: 1 March 1940 PDF downloadLoading ...