Renal Homotransplantation in Man
Authors: JULIO E. FIGUEROA
Journal: Annals of Internal Medicine (1964)

Article1 August 1964Renal Homotransplantation in ManReport of Six Consecutive CasesJULIO E. FIGUEROA, M.D., SATORU NAKAMOTO, M.D., EUGENE F. POUTASSE, M.D., WILLEM J. KOLFF, M.D.JULIO E. FIGUEROA, M.D.Search for more papers by this author, SATORU NAKAMOTO, M.D.Search for more papers by this author, EUGENE F. POUTASSE, M.D.Search for more papers by this author, WILLEM J. KOLFF, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-61-2-188 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThousands of persons die every year throughout the world because of chronic renal disease. The treatment of these patients, once the uremic stage is reached, has consisted mainly of palliation, dietary and fluid restriction, and electrolyte therapy, in an effort to restore the metabolic balance.The first major step towards more effective treatment of chronic uremia was accomplished in 1941, when the artificial kidney was introduced by Kolff (1). This technique, commonly used in the treatment of acute renal failure, now permits the maintenance of life in patients with virtually no renal function for prolonged periods of time (2, 3)....References1. KOLFF WJ: The artificial kidney: a dialyser with a great area. Acta Med. Scand. 117: 121, 1944. CrossrefGoogle Scholar2. SCRIBNERCANERBURIQUINTON BHJERW: The technique of continuous hemodialysis. Trans. Amer. Soc. Artif. Intern. Organs 6: 88, 1960. MedlineGoogle Scholar3. BRANDONNAKAMOTOROSENBAUMFRANKLINKOLFF JMSJLMWJ: Prolongation of survival by periodic prolonged hemodialysis in patients with chronic renal failure. Amer. J. Med. 33: 538, 1962. CrossrefMedlineGoogle Scholar4. ULLMANN E: Ueber Gewebs und Organ Transplantationen. Wien Klin. Wschr. 15: 281, 707, 1902. Google Scholar5. DEMPSTER WJ: Problems involved in the homotransplantation of tissues, with particular reference to skin. Brit. Med. J. 2: 1041, 1951. CrossrefMedlineGoogle Scholar6. DEMPSTER WJ: Kidney homotransplantation. Brit. J. Surg. 40: 447, 1953. CrossrefMedlineGoogle Scholar7. HUMEMERRILLMILLERTHORN DMJPBFGW: Experiences with renal homotransplantation in the human: report of nine cases. J. Clin. Invest. 34: 327, 1955. CrossrefMedlineGoogle Scholar8. HAMBURGERVAYSSECROSNIERAUVERTLALANNEHOPPER JJJJCMJ: Renal homotransplantation in man after radiation of recipient: experience with six patients since 1959. Amer. J. Med. 32: 854, 1962. CrossrefMedlineGoogle Scholar9. GOODWINMIMSKAUFMAN WEMMJJ: Human renal transplantation. III. Technical problems encountered in six cases of kidney homotransplantation. J. Urol. 89: 349, 1963. CrossrefMedlineGoogle Scholar10. HUMEMAGEEKAUFFMANRITTENBURYPROUT DMJHHMMSGR: Renal homotransplantation in man in modified recipients. Ann. Surg. 158: 608, 1963. CrossrefMedlineGoogle Scholar11. STARZLMARCHIOROTALMAGEWADDELL TETLDWWR: Splenectomy and thymectomy in human renal homotransplantation. Proc. Soc. Exp. Biol. Med. 113: 929, 1963. CrossrefMedlineGoogle Scholar12. MURRAYMERRILLHARRISONWILSONDAMMIN JEJPJHREGJ: Prolonged survival of human kidney homografts by immunosuppressive drug therapy. New Eng. J. Med. 268: 1315, 1963. CrossrefMedlineGoogle Scholar13. QUINTONDILLARDSCRIBNER WEDBH: Cannulation of blood vessels for prolonged hemodialysis. Trans. Amer. Soc. Artif. Intern. Organs 6: 104, 1960. MedlineGoogle Scholar14. MERRILLGIORDANOHEETDERKS JPCDR: Role of the kidney in human hypertension: failure of hypertension to develop in the renoprival subject. Amer. J. Med. 31: 931, 1961. CrossrefMedlineGoogle Scholar15. MERRILL JP: Transplantation of normal tissues. Physiol. Rev. 39: 860, 1959. CrossrefGoogle Scholar16. MILLER JF: Role of the thymus in immunity. Brit. Med. J. 5355: 459, 1963. CrossrefGoogle Scholar17. CALNEALEXANDREMURRAY RYJPJE: A study of the effect of drugs in prolonging survival of homologous renal transplants in dogs. Ann. NY Acad. Sci. 99: 743, 1962. CrossrefMedlineGoogle Scholar18. ALLEN AC: The Kidney. Medical and Surgical Diseases, 2d Ed., Grune and Stratton, Inc., New York, 1962, p. 184. Google Scholar19. PORTERTHOMSONOWENSKENYONMOWBRAYPEART KAWBKJRJFWS: Obliterative vascular changes in four human kidney homotransplants. Brit. Med. J. 5358: 639, 1963. CrossrefGoogle Scholar20. KOLFFNAKAMOTOPOUTASSESTRAFFONFIGUEROA WJSEFRAJE: The effect of bilateral nephrectomy and kidney transplantation on hypertension in man. Coun. High Blood Pressure Res., Cleveland, Ohio, Nov. 10, 1963. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Cleveland, OhioFrom the Departments of Artificial Organs and Urology, The Cleveland Clinic Foundation, Cleveland, Ohio.This work was supported in part by a grant from the John A. Hartford Foundation, Inc.Doctor Figueroa is a Fellow in the Department of Artificial Organs and recipient of Fellowship 1-F2-HE-20, 090-01, National Heart Institute, National Institutes of Health, United States Public Health Service, Bethesda, Md.Requests for reprints should be addressed to Willem J. Kolff, M.D., Department of Artificial Organs, Cleveland Clinic, Cleveland, Ohio. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byContinuous function of 80 primary renal allografts for 30–47 years with maintenance prednisone and azathioprine/mycophenolate mofetil therapy: A clinical mosaic of long‐term successesReflections on My Lifetime Teacher: Dr. Willem J. KolffPlasma Renin Activity in Hypertension After Renal HomotransplantationMANAGEMENT OF UREMIA IN OLDER PATIENTS: HEMODIALYSIS AND RENAL TRANSPLANTATION*Radioisotope Renal Function Studies in Human Renal Allografts: Value in the Differential Diagnosis of Oliguria in the Presence of Obstructive Disease with and Without Urinary ExtravasationNeurologic disorders in renal failureHuman Tissue TransplantationPeripheral Plasma Renin Activity in Renal-Homotransplant RecipientsUremic Pericarditis and Cardiac Tamponade in Chronic Renal FailureCLAUDE BEAUDRY, M.D., SATORU NAKAMOTO, M.D., WILLEM J. KOLFF, M.D., F.A.C.P.the course of renal hypertension after bilateral nephrectomy and transplantation*CONCENTRATION OF RENIN IN KIDNEYS OF PATIENTS WITH RENAL HYPERTENSION EFFECT OF A RENAL HOMOGRAFTTHE COURSE OF RENAL HYPERTENSION AFTER BILATERAL NEPHRECTOMY AND TRANSPLANTATION* 1 August 1964Volume 61, Issue 2Page: 188-207KeywordsGlomerulonephritisHomotransplantationHypertensionPatientsPrevention, policy, and public healthRenal diseasesRenal transplantationSepsisTransplantationUrology Issue Published: 1 August 1964 PDF downloadLoading ...