VITAMINS IN PEPTIC ULCER
Authors: Henry Field, William D. Robinson, Daniel Melnick
Journal: Annals of Internal Medicine (1940)

Article1 October 1940VITAMINS IN PEPTIC ULCERHENRY FIELD JR., M.D., WILLIAM D. ROBINSON, M.D., DANIEL MELNICK, Ph.D.HENRY FIELD JR., M.D.Search for more papers by this author, WILLIAM D. ROBINSON, M.D.Search for more papers by this author, DANIEL MELNICK, Ph.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-14-4-588 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptPeptic ulcers have been produced experimentally in animals by deficiencies in vitamins B1 and C.1, 2 Those were severe deficiencies and we do not have evidence that such deficiencies are usually important in the etiology of peptic ulcers in man. The possible significance of vitamins in the treatment of peptic ulcers, however, deserves serious consideration. Some conclusions, which we are to present, must be considered tentative because they are based, in part, on indirect evidence.Vitamin C may be important in respect to the process of healing of an ulcer or in respect to its tendency to bleed. In regard...Bibliography1. SMITHMCCONKEY DTM: Peptic ulcers (gastric, pyloric and duodenal); occurrence in guinea-pigs fed on a diet deficient in vitamin C, Arch. Int. Med., 1933, li, 413. CrossrefGoogle Scholar2. SURETHATCHER BHS: Avitaminosis; production of gastric ulcers in the albino rat as result of specific influence of deficiency of vitamin B1 , Arch. Path., 1933, xvi, 809. Google Scholar3. WOLBACHHOWE SBPR: Intercellular substance in experimental scorbutus, Arch. Path. and Lab. Med., 1926, i, 1. WOLBACH, S. B.: Controlled formation of collagen and reticulum. Study of source of intercellular substance in recovery from experimental scorbutus, Am. Jr. Path. (supp.), 1933, ix, 689. Google Scholar4. 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Author, Article, and Disclosure InformationAffiliations: Ann Arbor, Michigan*Read at the Cleveland meeting of the American College of Physicians April 4, 1940.From the Department of Internal Medicine, University of Michigan, School of Medicine, Ann Arbor, Michigan, assisted by a grant from the Horace H. Rackham School of Graduate Studies.†Upjohn Fellow in Clinical Research, 1938-1940.‡Upjohn Fellow in Clinical Research, 1937 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byWater-Soluble Vitamin Deficiencies in Complicated Peptic Ulcer Patients Soon after Ulcer Onset in JapanComparative Studies of Ascorbic Acid Levels in Gastric Secretion and BloodThe Bland Diet in Ulcer TherapyPhysiological Availability of the VitaminsAcute gastroduodenal perforationsVitamins and the General PractitionerStudies on ascorbic acid deficiency in Gastric diseases: incidence, diagnosis and treatment 1 October 1940Volume 14, Issue 4Page: 588-592KeywordsEtiologyGraduate medical educationPeptic ulcersUlcersVitamin CVitamins ePublished: 1 December 2008 Issue Published: 1 October 1940 PDF downloadLoading ...