RECENT ADVANCES IN CARBOHYDRATE METABOLISM WITH PARTICULAR REFERENCE TO DIABETES MELLITUS
Authors: C. N. H. Long
Journal: Annals of Internal Medicine (1935)

Article1 August 1935RECENT ADVANCES IN CARBOHYDRATE METABOLISM WITH PARTICULAR REFERENCE TO DIABETES MELLITUSC. N. H. LONG, M.D., D.Sc.C. N. H. LONG, M.D., D.Sc.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-9-2-166 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSince the discovery of von Mering and Minkowski some 46 years ago, that total extirpation of the pancreas in animals produced a condition indistinguishable from diabetes mellitus in man, three major problems have confronted both physiologists and clinicians interested in this disease. They are: 1. The isolation and clinical application of the internal secretion of the pancreas. 2. The mode of action of this pancreatic hormone. 3. The elucidation of the mechanisms involved in the production of the diabetic syndrome.The first problem was solved in 1922 when Banting and Best succeeded in preparing insulin. This discovery was at once...Bibliography1. BLUM F: Über Nebennierendiabetes, Deutsch. Arch. f. klin. Med., 1901, lxxi, 146. Google Scholar2. CORI CF: Mammalian carbohydrate metabolism, Physiol. Rev., 1931, xi, 143-275. CrossrefGoogle Scholar3. HOUSSAYBIASOTTI BAA: Hypophysis, carbohydrate metabolism and diabetes, Endocrinology, 1931, xv, 511-523. CrossrefGoogle Scholar4. HOUSSAYBIASOTTI BAA: Hypophysektomie und Pankreasdiabetes dei der Kröte, Arch. f. d. ges. Physiol., 1931, ccxxvii, 239-250. CrossrefGoogle Scholar5. HOUSSAYBIASOTTIRIETTI BAACT: Acción diabetógena del extracto ántero-hipofisario, Revista de la Soc. argent. de biol., 1932, viii, 469-481. Google Scholar6. HOUSSAYBIASOTTIDE BENEDETTORIETTI BAAECT: Acción diabetógena de los extractos ántero-hipofisarios, Rev. de la Soc. argent. de biol., 1932, viii, 563-569. Google Scholar7. EVANSMEYERSIMPSONREICHERT HMKMEFL: Disturbance of carbohydrate metabolism in normal dogs injected with hypophyseal growth hormone, Proc. Soc. Exper. Biol. and Med., 1932, xxix, 857-858. CrossrefGoogle Scholar8. BAUMANNMARINE EJD: Glycosuria in rabbits following injections of saline extract of anterior pituitary, Proc. Soc. Exper. Biol. and Med., 1932, xxix, 1220-1223. CrossrefGoogle Scholar9. HRUBETZ MC: Pituitary hormones and the blood sugar level, Proc. Soc. Exper. Biol. and Med., 1935, xxxii, 842. CrossrefGoogle Scholar10. BARNESSCOTTFERRILLROGOFF BOVBHWJM: Effects of partial adrenalectomy on experimental diabetes and on sensitivity to insulin, Proc. Soc. Exper. Biol. and Med., 1934, xxxi, 524-525. CrossrefGoogle Scholar11. BARNESDIXROGOFF BOASJM: Effect of adrenalin on insulin sensitivity of partially adrenalectomized and of hypophysectomized dogs, Proc. Soc. Exper. Biol. and Med., 1934, xxxi, 1145-1146. CrossrefGoogle Scholar12. DE TAKATSFENNTRUMP GGKRA: Splanchnic nerve section in juvenile diabetic, ANN. INT. MED., 1934, vii, 1201-1217. LinkGoogle Scholar13. BRITTONSILVETTE SWH: Apparent prepotent function of adrenal glands, Am. Jr. Physiol., 1932, c, 701-713. CrossrefGoogle Scholar14. ZWEMERSULLIVAN RLRC: Blood chemistry of adrenal insufficiency in cats, Endocrinology, 1934, xviii, 97-106. CrossrefGoogle Scholar15. HARTMANBROWNELL FAKA: Relation of adrenals to diabetes, Proc. Soc. Exper. Biol. and Med., 1934, xxxi, 834-835. CrossrefGoogle Scholar16. BIASOTTIHOUSSAY ABA: Phlorrhizin diabetes in fasting or fed hypophysectomized dogs, Jr. Physiol., 1932, lxxvii, 81-91. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Philadelphia, Pennsylvania*Read at the Philadelphia meeting of the American College of Physicians, May 3, 1935.From the George S. Cox Medical Research Institute, University of Pennsylvania, Philadelphia. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDie Grundstoffe der NahrungExperimental Hyperglycemic States Not Primarily Due to a Lack of InsulinErnährungskrankheitenErnährungskrankheitenExperimental Glycosuria: Its Production, Prevention, and AlleviationPrüfung der endokrinen FunktionenThe Chemistry and Physiology of the Thyroid HormoneDer Diabetes mellitusCarbohydrate Metabolism in the Practice of Medicine*Die Wachstums- und stoffwechselwirksamen Wirkstoffe des HVLSTUDIES ON THE THYROID GLAND X PANCREAS, HYPOPHYSIS AND THYROID IN CHILDREN OF DIABETIC MOTHERS1The role of the liver as the commissariat of the bodyInsulin 1 August 1935Volume 9, Issue 2Page: 166-174KeywordsCarbohydrate metabolismDiabetes mellitusHormonesInsulinPancreas ePublished: 1 December 2008 Issue Published: 1 August 1935 PDF downloadLoading ...