tbuckley/cabot-search huggingface dataset:
Abstract 15301: Skilled Nursing Facilities and 30-day Hospital Readmissions in Heart Failure
Authors: Sheila M Manemann, Alanna M Chamberlain, Jennifer St. Sauver, Susan A Weston, Ruoxiang Jiang, Veronique L Roger
Journal: Circulation (2014)

Background: Referral to a skilled nursing facility (SNF) should contribute to reducing hospital readmissions; however, a “revolving door” phenomenon after admission to SNF has been hypothesized to drive readmissions. The urgent need to study the impact of SNF on readmissions in heart failure (HF) was recently emphasized, yet this has never been studied in the community. Objectives: To evaluate the association between discharge to SNF and 30-day readmissions in a community cohort of hospitalized incident HF patients. Methods: Olmsted County, MN residents hospitalized with first ever (incident) HF (International Classification of Diseases-9 th Revision code 428) from 1995 through 2010 were identified. HF was validated by Framingham criteria. Patients residing in a SNF prior to hospitalization were excluded from the analysis. Logistic regression was used to examine the association between discharge to SNF and 30-day readmissions. Results: Among 1360 HF patients (mean age 74±14, 47% male), 241(18%) were referred to a SNF. Overall, 296 (22%) patients were readmitted within 30-days after index hospitalization. The proportion of 30-day readmissions was greater among patients discharged to a SNF compared to patients discharged home (27% vs 21%, p=0.031). After adjustment for age and sex, patients discharged to a SNF had a 40% increase in the odds of having a hospital readmission within 30 days post HF compared to those discharged home (OR: 1.42, 95% CI 1.01-1.99). Further adjustment for year of HF diagnosis, ejection fraction, anemia, renal function, dementia and cancer did not alter the strength of the association (OR: 1.43, 95% CI: 0.99-2.09). Conclusion: Among community patients with HF, 30-day readmissions remain frequent and are more likely to occur among patients discharged to a SNF compared to those discharged home. These data provide new insight into the drivers of HF readmissions and suggest that interventions targeted to HF patients in SNFs may be warranted.
Health select committee criticises public health directors
Authors: Rhona MacDonald
Journal: BMJ (2001)

Directors of public health were criticised by the parliamentary select committee on health last week for not providing the necessary leadership in the public health field.

The report, which primarily covers England, set out to establish to what extent the Department of Health's actions are taking “public health out of the ghetto.” According to the report, “public health is not a term understood by the majority of the public. It can be variously defined so as to cover trends of disease in a population, the provision of preventative and health improving care, or a range of health-impacting factors.”

The report also criticises the government for the slow development of initiatives to “battle against health inequalities,” such as health action zones. It states that this is due to “profound systemic and structural problems which relate to the lack of co-ordination between different Government departments, statutory agents, elected authorities and the voluntary sector.”
Letter by Nairooz et al Regarding Article, “Improved Quality of Life After 1 Year With an Invasive Versus a Noninvasive Treatment Strategy in Claudicants: One-Year Results of the Invasive Revascularization or Not in Intermittent Claudication (IRONIC) Trial”
Authors: Ramez Nairooz, Srikanth Vallurupalli, Mayank Agrawal
Journal: Circulation (2015)
Abstract 3475: Negative impact of evaporation on cervical cancer cells during long term incubation is alleviated by Thermo Scientific Edge plate
Authors: Cindy Neeley, Sarah Verna
Journal: Cancer Research (2014)

Abstract With more than half a million new cases and 275,000 deaths each year, cervical cancer ranks as the third and the fourth most common cause of cancer incidence and mortality, respectively, in women worldwide. Prophylactics, screening, testing, and treatment options for cervical cancer lead to an increasing need for new and innovative technologies. Microplates are widely engaged in all aspects of cervical cancer research. However, researchers have long struggled with media evaporation from the perimeter wells of their microplates. This condition negatively affects research results and lab productivity. In this study, we demonstrated that human cervical cancer HeLa cells suffered significant reduction in cell viability over 7-day incubation in the perimeter wells of standard 96-well plate. HeLa cells in these wells underwent premature NFκB nuclear translocation suggesting the onset of cell stress during culture. In comparison, study using the Thermo Scientific Edge plate with an innovative design of “build-in” mote showed significantly less evaporation from the perimeter wells. The variations between perimeter wells and center wells were minimal in Edge plate, indicating uniformed performance across the entire plate. Advantages of Edge plate were further demonstrated by the improvement in HeLa cell viability in perimeter wells when compared to standard 96-well plate. HeLa cells cultured in Edge plate were in a much healthier state and only demonstrated NFκB nuclear translocation when stress-inducing agent TNF-α was applied to the culture. In summary, Edge plate allows the use of all 96 wells without the concern of evaporation, resulting in improved consistency in assay models for in vitro research of cervical and other types of cancer. Citation Format: Cindy Neeley, Sarah Verna. Negative impact of evaporation on cervical cancer cells during long term incubation is alleviated by Thermo Scientific Edge plate. [abstract]. In: Proceedings of the 105th Annual Meeting of the American Association for Cancer Research; 2014 Apr 5-9; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2014;74(19 Suppl):Abstract nr 3475. doi:10.1158/1538-7445.AM2014-3475
US cancer care is worse due to more paperwork
Authors: Susan Mayor
Journal: BMJ (2001)

US cancer specialists are calling for reform of administrative measures designed to reduce healthcare fraud that have resulted in so much paperwork that patient care is suffering, according to results from a survey presented earlier this week.

The survey of more than 2500 clinical oncologists showed that the amount of time they spend filling out paperwork and documenting patient care has increased more than fourfold over the past 25 years.

The average time spent with patients remained constant over this period, but the doctors taking part in the survey considered that far more …
Health Policy Platforms
Authors: Mike Mitka
Journal: JAMA (2004)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Ventricular Arrhythmias and Implantable Cardioverter-Defibrillator Therapy in Patients With Continuous-Flow Left Ventricular Assist Devices
Authors: Arthur R. Garan, Melana Yuzefpolskaya, Paolo C. Colombo, John P. Morrow, Rosie Te-Frey, Drew Dano, Hiroo Takayama, Yoshifumi Naka, Hasan Garan, Ulrich P. Jorde, Nir Uriel
Journal: Journal of the American College of Cardiology (2013)
THE IN VITRO INCORPORATION OF 14C-ACETATE INTO THE ISOLATED SEBACEOUS GLANDS AND APPENDAGE-FREED EPIDERMIS OF HUMAN SKIN.
Authors: ROY SUMMERLY, SHEILA WOODBURY
Journal: British Journal of Dermatology (1971)

Journal Article THE IN VITRO INCORPORATION OF 14C‐ACETATE INTO THE ISOLATED SEBACEOUS GLANDS AND APPENDAGE‐FREED EPIDERMIS OF HUMAN SKIN: A TECHNIQUE FOR THE STUDY OF LIPID SYNTHESIS IN THE ISOLATED SEBACEOUS GLAND Get access ROY SUMMERLY, ROY SUMMERLY M.R.C. Unit on the Experimental Pathology of Skin, The Medical School, Birmingham 15 and the Skin Department, North Staffordshire Hospital Centre, Stoke‐on‐Trent, Staffs Search for other works by this author on: Oxford Academic Google Scholar SHEILA WOODBURY SHEILA WOODBURY M.R.C. Unit on the Experimental Pathology of Skin, The Medical School, Birmingham 15 and the Skin Department, North Staffordshire Hospital Centre, Stoke‐on‐Trent, Staffs Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 85, Issue 5, 1 November 1971, Pages 424–431, https://doi.org/10.1111/j.1365-2133.1971.tb14048.x Published: 01 November 1971 Article history Accepted: 28 June 1971 Published: 01 November 1971
Adolescent Health Care: A Practical Guide.
Authors: Lawrence S. Neinstein
Journal: Annals of Internal Medicine (1991)

GENERAL CONSIDERATIONS IN ADOLESCENT CARE: Normal Physical Growth & Development / Psychosocial Development in Normal Adolescents / The Office Visit, Interview Techniques & Recommendations to Parents / Preventive Healthcare for the Adolescent / Vital Statistics & Injuries / Nutrition / Understanding Legal Aspects of Care ENDOCRINE PROBLEMS: Abnormal Growth & Development / Thyroid Disease in Adolescents / Diabetes Mellitus / Gynecomastia CARDIOVASCULAR PROBLEMS: Cardiac Risk Factors & Hyperlipidemia / Hypertension / Heart Murmurs including MVP ORTHOPEDIC PROBLEMS: Scoliosis and Kyphosis / Common Orthopedic Problems / Back Pain / Guidelines in Sports Medicine DERMATOLOGIC DISORDERS: Acne / Miscellaneous Dermatologic Disorders NEUROLOGICAL DISORDERS: Epilepsy / Headaches / Syncope & Vertigo / Sleep Disorders GENITOURINARY DISORDERS: Genitourinary Tract Disorders / Enuresis / Asymptomatic Proteinuria & Hematuria / Scrotal Disorders INFECTIOUS DISEASES: Infectious Mononucleosis & Mycoplasma Pneumoniae / Hepatitis / HIV Infections & AIDS CONDITIONS AFFECTING NUTRITION & WEIGHT: Obesity / Anorexia Nervosa & Bulimia Nervosa PSYCHOSOMATIC ILLNESSES & OTHER MEDICAL DISORDERS: Psychosomatic Illnesses in Adolescents / Fatigue / Chronic Abdominal Pain / Chest Pain / Fibromyalgia Syndrome & Reflex Sympathetic Dystrophy SEXUALITY & CONTRACEPTION: Adolescent Sexuality / Gay, Lesbian, Bisexual & Transgender Adolescents / Teen Pregnancy / Contraception / Combination Hormonal Contraceptives / Intrauterine Contraception / Barrier Contraceptives / Emergency Contraception / Long-Acting Progestins ADOLESCENT GYNECOLOGY: Gynecological Examination / Normal Menstrual Physiology / Dysmenorrhea / Dysfunctional Uterine Bleeding / Amenorrhea & PCO / Pelvic Masses / Abnormal Pap Smear / Vaginitis & Vaginosis / Ectopic Pregnancy & Other Pregnancy Complications / Galactorrhea / Hirsutism & Virilization / Breast Disorders SEXUALLY TRANSMITTED DISEASES: Overview of Sexually Transmitted Diseases / Gonorrhea / Chlamydia Trachomatis Infections / Pelvic Inflammatory Disease / Syphilis / Herpes Genitalis / HPV & Anogenital Warts / Other STIs including Genital Ulcers, Pediculosis, Scabies & Molluscum DRUG USE & ABUSE: Overview of Drug Use & Abuse / Alcohol / Tobacco / Psychoactive Substances of Abuse Used by Adolescents / Laboratory Testing of Substances of Abuse / Office Management of Substances of Use & Abuse / Intensive Drug Treatment PSYCHOSOCIAL PROBLEMS & CONCERNS: Common Concerns of Adolescents & Their Parents / High-Risk & Out-of-Control Behavior / Youth Violence / Adolescent Depression & Anxiety Disorders / Suicide / School Problems / Sexual Assault & Victimization / Chronic Illness in the Adolescent / Herbal Medications & Complementary Medicine / Overview of College Health APPENDICES
Discharge Aspirin Dose and Clinical Outcomes in Patients With Acute Coronary Syndromes Treated With Prasugrel Versus Clopidogrel
Authors: Payal Kohli, Jacob A. Udell, Sabina A. Murphy, Christopher P. Cannon, Elliott M. Antman, Eugene Braunwald, Stephen D. Wiviott
Journal: Journal of the American College of Cardiology (2013)
Abstract 15897: Microalbuminuria is Associated With Subclinical Cardiovascular Disease Parameters Independent of Traditional Risk Factors in a Large Population Based Study
Authors: Mohan Thanikachalam, Abirami Swaminathan, Jahnavi Sunderarajan, Vijaykumar Harivanzan, Sadagopan Thanikachalam
Journal: Circulation (2014)

Background: To reduce the burden of cardiovascular disease (CVD), management strategies are increasingly focusing on preventive measures following early detection of markers of CVD. Microalbuminuria (MA) is gaining recognition as a simple marker of CVD. MA is an independent predictor of cardiovascular (CV) mortality, but the association between MA and CVD is not fully defined. In the current study we aimed to assess the relationship between MA and subclinical CVD parameters.

Methods: We conducted a population-based study in 8,080 South Indians, which included morning urine samples for albumin and creatinine levels for calculating MA, glucose tolerance test, anthropometric, physical activity, blood pressure, fasting blood for lipid levels and other biomarker assessments. Other assessments included left ventricular mass indexed (LVMI) to body surface area by echocardiograph, carotid intimal medial thickness (IMT), arterial stiffness by carotid-femoral pulse wave velocity (PWV) and endothelial function by brachial artery flow mediated dilatation (FMD).

Results: After the exclusion of people with evidence of coronary artery disease, 7164 subjects (mean age 43 years, 58% women) constituted the study sample. The value of subclinical CV parameters by MA quartiles is shown in the Table. In univariate analysis MA level was associated with PWV (r = 0.14, P < 0.01), LVMI (r = 0.14, P < 0.01), FMD (r = -0.030, P < 0.01) and IMT (r = 0.077, P < 0.01). In multi-linear models after adjusting for age, sex, smoking, physical activity, BMI, diabetes, hypertension, triglyceride, LDL and HDL levels, MA was independently associated with PWV ( = 0.067, P < 0.01), LVMI ( = 0.091, P < 0.01) and IMT ( = 0.043, P < 0.01).

Conclusion: MA was associated with subclinical CVD parameters independent of traditional CVD risk factors. MA could be a simple marker of subclinical CVD and periodic screening for MA could allow for early identification subclinical disease and intervention.

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Debridement with prosthesis retention and antibiotherapy vs. two-stage revision for periprosthetic knee infection within 3 months after arthroplasty: a case–control study
Authors: A. Lizaur-Utrilla, S. Gonzalez-Parreño, V. Gil-Guillen, F.A. Lopez-Prats
Journal: Clinical Microbiology and Infection (2015)
Pediatric Clinical Ethics Consultations at an Academic Medical Center: Does One Size Fit All?
Authors: Joan Henriksen Hellyer, Brenda Schiltz, Wendy Moon, Michelle Grafelman, Kei Yoshimatsu, Keith M. Swetz
Journal: The American Journal of Bioethics (2015)

We applaud the efforts of Johnson and colleagues (2015) in summarizing their experience with pediatric ethics consultation (PEC) and in contributing to the scarce literature characterizing PEC. We ...
Identification of Bruton's tyrosine kinase (Btk) gene mutations and characterization of the derived proteins in 35 X-linked agammaglobulinemia families: a nationwide study of Btk deficiency in Japan
Authors: S Hashimoto, S Tsukada, M Matsushita, T Miyawaki, Y Niida, A Yachie, S Kobayashi, T Iwata, H Hayakawa, H Matsuoka, I Tsuge, T Yamadori, T Kunikata, S Arai, K Yoshizaki, N Taniguchi, T Kishimoto
Journal: Blood (1996)
TUBERCULOMA OF THE BRAIN
Authors: Maurice Lewison, Ellis B. Freilich, Oscar B. Ragins
Journal: Annals of Internal Medicine (1934)

Article1 March 1934TUBERCULOMA OF THE BRAINMAURICE LEWISON, M.D., F.A.C.P., ELLIS B. FREILICH, M.D., OSCAR B. RAGINS, M.D.MAURICE LEWISON, M.D., F.A.C.P.Search for more papers by this author, ELLIS B. FREILICH, M.D.Search for more papers by this author, OSCAR B. RAGINS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-7-9-1141 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn an analysis of 757 autopsies performed at the Cook County Hospital from 1917 to 1927 inclusive, on patients who had died of tuberculosis, 20 instances of the occurrence of tuberculoma of the brain were discovered. It is the purpose of this paper to present briefly certain clinical and pathologic data which have been drawn from the records of these cases. In some instances desired information has not been available. This is due in part to the fact that the condition was not usually suspected during the patients' life time, only two cases having been diagnosed ante mortem.The literature...1. ANDERSON FN: Tuberculoma of central nervous system, Arch. Neurol. and Psychiat., 1928, xx, 354-365. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Chicago, Illinois*Received for publication November 13, 1933. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byComplications of miliary tuberculosis: low mortality and predictive biomarkers from a UK cohortTEST YOUR DIAGNOSTIC SKILLBeitrag zur Morphologie und Biologie der entz�ndlichen, raumfordernden, intrakraniellen ProzesseTuberkulome im Bereich eines alten Hirnschu�kanalesAllgemeine RöntgensymptomatologieIntrakranielle VerkalkungenTUBERCULOMAS OF THE CENTRAL NERVOUS SYSTEM: REVIEW AND REPORT OF FOUR CASES SUCCESSFULLY MANAGED WITH SURGERY AND CHEMOTHERAPY*MORTON SCHWARTZ, M.D., RICHARD A. GILMAN, M.D., JOHN S. ROBEY, M.D., JANET SETTLE, M.D., LELAND E. PADDOCK, M.D. 1 March 1934Volume 7, Issue 9Page: 1141-1145KeywordsAutopsyBrain ePublished: 1 December 2008 Issue Published: 1 March 1934 PDF downloadLoading ...
Withdrawing low risk women from cervical screening programmes: mathematical modelling study Commentary: trials versus models in appraising screening programmes
Authors: C Sherlaw-Johnson, S Gallivan, D Jenkins, G. Royston
Journal: BMJ (1999)

To evaluate the impact of policies for removing women before the recommended age of 64 from screening programmes for cervical cancer in the United Kingdom.A mathematical model of the clinical course of precancerous lesions which accounts for the influence of infection with the human papillomavirus, the effects of screening on the progression of disease, and the accuracy of the testing procedures. Two policies are compared: one in which women are withdrawn from the programme if their current smear is negative and they have a recent history of regular, negative results and one in which women are withdrawn if their current smear test is negative and a simultaneous test is negative for exposure to high risk types of human papillomavirus.United Kingdom cervical screening programme.The incidence of invasive cervical cancer and the use of resources.Early withdrawal of selected women from the programme is predicted to give rise to resource savings of up to 25% for smear tests and 18% for colposcopies when withdrawal occurs from age 50, the youngest age considered in the study. An increase in the incidence of invasive cervical cancer, by up to 2 cases/100 000 women each year is predicted. Testing for human papillomavirus infection to determine which women should be withdrawn from the programme makes little difference to outcome.This model systematically analyses the consequences of screening options using available data and the clinical course of precancerous lesions. If further audit studies confirm the model's forecasts, a policy of early withdrawal might be considered. This would be likely to release substantial resources which could be channelled into other aspects of health care or may be more effectively used within the cervical screening programme to counteract the possible increase in cancer incidence that early withdrawal might bring.
Nabumetone-associated pseudoporphyria
Authors: F. Antony, A.M. Layton
Journal: British Journal of Dermatology (2000)

Journal Article Nabumetone‐associated pseudoporphyria Get access F. Antony, F. Antony Department of Dermatology, Harrogate District Hospital, Lancaster Park Road, Harrogate, North Yorkshire HG2 7SX, U.K. Search for other works by this author on: Oxford Academic Google Scholar A.M. Layton A.M. Layton Department of Dermatology, Harrogate District Hospital, Lancaster Park Road, Harrogate, North Yorkshire HG2 7SX, U.K. Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 142, Issue 5, 1 May 2000, Pages 1067–1069, https://doi.org/10.1046/j.1365-2133.2000.03516.x Published: 01 May 2000
Advances in Pediatric Dermatology
Authors: L Lamberg
Journal: JAMA (2001)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The neuronal repressor REST/NRSF is an essential regulator in medulloblastoma cells
Authors: Patrick Lawinger, Radjendirane Venugopal, Zong-Sheng Guo, Anand Immaneni, Devjani Sengupta, Wenying Lu, Luca Rastelli, Ana Marin Dias Carneiro, Victor Levin, Gregory N. Fuller, Yann Echelard, Sadhan Majumder
Journal: Nature Medicine (2000)