HYPERPROTEINEMIA, AUTOHEMAGGLUTINATION, RENAL INSUFFICIENCY AND ABNORMAL BLEEDING IN MULTIPLE MYELOMA
Authors: Alvin G. Foord
Journal: Annals of Internal Medicine (1935)

Article1 March 1935HYPERPROTEINEMIA, AUTOHEMAGGLUTINATION, RENAL INSUFFICIENCY AND ABNORMAL BLEEDING IN MULTIPLE MYELOMAALVIN G. FOORD, M.D., F.A.C.P.ALVIN G. FOORD, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-8-9-1071 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptMultiple myeloma cases notoriously present bizarre clinical syndromes often diagnosed as arthritis, neuritis, severe anemias, or chronic nephritis, etc., depending on the predominance of various symptoms or findings such as pain, pallor, or urinary or blood nitrogen findings respectively.Likewise many unique chemical and hematological findings are reported, most of which are neither entirely explained nor satisfactorily related to the underlying disorder. Reimann,1however, first called attention to the cause of the autohemagglutination seen in the blood of a patient who had been treated for arthritis for months. The fact that this patient's red cells formed tight rouleaux in smears...Bibliography1. REIMANN HA: Hyperproteinemia as a cause of autohemagglutination; observations in case of myeloma, Jr. Am. Med. Assoc., 1932, xcix, 1411-1414. CrossrefGoogle Scholar2. BÖNNIGER M: Ein seltener Blutbefund (Hyperproteinämie bei Myelomkrankheit), Deutsch. med. Wchnschr., 1933, lix, 770-771. Google Scholar3. FREUNDMAGNUS-LEVY RA: Multiple Myelome; über Besonderheiten der Blutzusammensetzung, Ztschr. f. klin. Med., 1932, cxxi, 1-13. Google Scholar4. FAHRAEUS R: Suspension stability of blood, Physiol. Rev., 1929, ix, 241-274. CrossrefGoogle Scholar5. BARKER LF: Discussion of nature and relationships of multiple myeloma with illustrative case, Med. Clin. N. Am., 1933, xvi, 1019-1027. Google Scholar6. 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JACKSONPARKERBETHEA HFJM: Studies of diseases of lymphoid and myeloid tissues; plasmatocytomata and their relation to multiple myelomata, Am. Jr. Med. Sci., 1931, clxxxi, 169-180. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Pasadena, California*Read before the Section of Pathology and Physiology at the Eighty-Fifth Annual Session of the American Medical Association, Cleveland, June 14, 1934.From the Laboratories of the Pasadena Hospital, Pasadena, California, and the Pathology Department of the University of Southern California Medical School. 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