AN ETIOLOGY OF SCLERODERMA
Authors: I MUFSON
Journal: Annals of Internal Medicine (1953)

Article1 December 1953AN ETIOLOGY OF SCLERODERMAISIDOR MUFSON, M.D., F.A.C.P.ISIDOR MUFSON, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-39-6-1219 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptWhen the etiology of a disease is unknown its treatment is at best haphazard. This has heretofore been the fate of Raynaud's disease and scleroderma. From an analysis of clinical material,5we concluded that the vasospasm of minute vessels which characterizes Raynaud's disease is the somatic manifestation of a chronic psychologic derangement. This viewpoint has since found support.3, 9At that time evidence was available that scleroderma had the same origin. We now present analyses of our clinical findings which make more evident the relationship of Raynaud's disease to scleroderma. They are one disease, and differ only in the intensity...Bibliography1. Craig JB: Psychogenesis of Raynaud's syndrome, Dis. Nerv. System 5: 142, 1944. Google Scholar2. LipkinMcDevittSchwartzDuryee MEMSAW: On the effects of suggestion in the treatment of vasospastic disorders of the extremities, Psychosom. Med. 7: 152, 1945. CrossrefGoogle Scholar3. MilletLiefMittelmann JAHB: Psychosomatic aspects of Raynaud's disease, presented at the Psychosomatic Forum of the American Psychosomatic Society, March 17, 1951. Google Scholar4. MittelmannWolff BHG: Emotions and skin temperature: observations on patients during psychotherapeutic (psycho-analytic) interviews, Pychosom. Med. 5: 211, 1943. CrossrefGoogle Scholar5. Mufson I: The mechanism and treatment of Raynaud's disease; a psychosomatic disturbance, Ann. Int. Med. 20: 228, 1944. LinkGoogle Scholar6. Mufson I: Treatment of peripheral arterial obliterative diseases and their complications by arterial infusions of histamine, Am. J. Med. 12: 680-687, 1952. CrossrefMedlineGoogle Scholar7. Mufson I: Responses of abnormal arterial circulation to various stimuli, as studied by use of radioactive sodium. II. Intraarterial histamine, papaverine, aminophylline and adrenalin: sympathectomy and Etamon, pain, Ann. Int. Med. 34: 428-441, 1951. LinkGoogle Scholar8. SimpsonBrownAdson SLGEAW: Raynaud's disease: evidence that it is a type of vasomotor neurosis, Arch. Neurol. and Psychiat. 26: 687, 1931. CrossrefGoogle Scholar9. Weiss EJ: Psychogenic peripheral spasm, Psychosom. Med. 8: 274, 1946. CrossrefMedlineGoogle Scholar10. White JC: Discussion Case Reports, New England J. Med. 247: 133-138, 1952. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Received for publication March 28, 1953.From Section of Peripheral Vascular Diseases, General Medicine, Hospital for Joint Diseases, New York, N. Y. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byBiofeedback and Raynaud’s DiathesisProgressive Systemic Sclerosis: Disorders of the MicrocirculationA review of recent observations and current theories on the etiology and pathogenesis of progressive systemic sclerosis (diffuse scleroderma)Krankheiten der GefäßeAcroparaesthesiae in Sclerodactyly and Carpal Tunnel Syndrome Treated with PrednisoloneRHEUMATISM AND ARTHRITIS REVIEW OF AMERICAN AND ENGLISH LITERATURE OF RECENT YEARS (ELEVENTH RHEUMATISM REVIEW)* Part IIWILLIAM D. ROBINSON, M.D., F.A.C.P., JOSEPH J. BUNIM, M.D., F.A.C.P., WILLIAM S. CLARK, M.D., DARRELL C. CRAIN, M.D., F.A.C.P., EPHRAIM P. ENGLEMAN, M.D., F.A.C.P., DONALD C. GRAHAM, M.D., F.R.C.P. (C), MAX M. MONTGOMERY, M.D., F.A.C.P., BERNARD M. NORCROSS, M.D., F.A.C.P., CHARLES RAGAN, M.D., F.A.C.P., MARIAN W. ROPES, M.D., F.A.C.P., EDWARD F. ROSENBERG, M.D., F.A.C.P., CHARLEY J. SMYTH, M.D., F.A.C.P.Periphere Gefäßkrankheiten 1 December 1953Volume 39, Issue 6Page: 1219-1227KeywordsEtiologyHospital medicinePeripheral vascular diseaseSclerodermaVascular diseasesVascular medicine ePublished: 1 December 2008 Issue Published: 1 December 1953 PDF downloadLoading ...