CHRONIC HYPERTROPHY OF THE SKIN AND LONG BONES: AN OSTEO-DERMOPATHIC SYNDROME
Authors: Irving Leinwand, A. Wilbur Duryee
Journal: Annals of Internal Medicine (1943)

Case Reports1 December 1943CHRONIC HYPERTROPHY OF THE SKIN AND LONG BONES: AN OSTEO-DERMOPATHIC SYNDROMEIRVING LEINWAND, M.D., A. WILBUR DURYEE, M.D., F.A.C.P.IRVING LEINWAND, M.D.Search for more papers by this author, A. WILBUR DURYEE, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-19-6-1018 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn 1926 M. Labbé and P. Renault1observed a case of "hypertrophic osteo-dermopathology." In 1927 Gronberg2described the syndrome "Magalia cutis et osseum." He collected nine similar cases from the literature in the preceding 16 years. In 1935, Touraine, Solente and Golé3designated and described "un syndrome osteo-dermapathique." This syndrome is characterized by lesions of thickened skin with furrowing of the scalp, forehead, face, and extremities associated with elephantiasis of the long bones without involvement of the joints. They reported several cases which had been previously classified as dermatological, associated with a pulmonary osteoarthropathy. These skin lesions were usually diagnosed...Bibliography1. LABBÉRENAULT MP: Hypertrophic osteodermopathy, Bull. et mém. Soc. méd. d. hôp. de Par., 1926, l, 1065-1067. Google Scholar2. GRONBERG A: Is cutis verticis gyrata a symptom in an endocrine syndrome which has so far received little attention? Acta med. Scandinav., 1927, lxvii, 24-42. Google Scholar3. TOURAINESOLENTEGOLÉ AGL: Un syndrome osteodermopathique: la pachyderme plicaturé avec pachyperiostose des extremites, Presse méd., 1935, xliii, 1820-1824. Google Scholar4. MEILBERGER M: Über elephantiatische Lidveränderungen zugleich ein Beitrag zur Kenntnis des osteodermopathischen Syndrome Touraine-Solente-Golé, Basel Theses, 1936. Google Scholar5. ROY JN: A propos de la pachyderme plicature avec pachyperiostose des extremites, Presse méd., 1937, xlv, 403-404. Google Scholar6. RINTELEN F: Über elephantiatische Lidveränderungen zugleich ein Beitrag zur Kenntnis des osteodermopathischen Syndrome Touraine-Solente-Golé, Ztschr. f. Augenheilk., 1937, xcii, 1. Google Scholar7. GIOMO F: Su di un caso di pachydermia con pachyperiostosi della estremita, Minerva Med., 1937, i, 577. Google Scholar8. BAMBERGER E: Über Knochenveränderungen bei chronischen Lungen und Herz-Krankheiten, Ztschr. f. klin. Med., 1890, xviii, 183. Google Scholar9. MARIE P: del'osteo-arthropathie hypertrophiante pneumonique, Rev. de méd., 1890, x, 1-36. Google Scholar10. CAMPBELLSACASACAMP DCCFJD: Hypertrophic (chronic) osteo-arthropathy, Proc. Staff Meet. Mayo Clin., 1938, xiii, 708-712. Google Scholar11. ARNOLD J: Acromegalie, Pachyarcrie oder Ostitis, Beitr. z. path. Anat. u. z. allg. Path., 1891, x, 1-8. Google Scholar12. OEHME C: Familiäre akromegalicähnliche Erkrankung besonders des Skellettes, Deutsch. med. Wchnschr., 1919, xlv, 207-209. CrossrefGoogle Scholar13. MULLER W: Über die familiäre akromegalicähnliche Skeletterkrankung, Beitr. z. klin. Chir., 1930, cl, 616-628. Google Scholar14. FREUND E: Idiopathic familial generalized osteophytosis, Am. Jr. Roentgenol., 1938, xxxix, 216-227. Google Scholar15. GARDNERPFEIFFER WUCH: Skeletal changes in mice receiving estrogens, Proc. Soc. Exper. Biol. and Med., 1938, xxxvii, 678. CrossrefGoogle Scholar16. SUTRO CJ: Effects of subcutaneous injection of estrogen upon skeleton in immature mice, Proc. Soc. Exper. Biol. and Med., xliv, 151-154. Google Scholar17. WENTWORTHSMITHGARDNER JHPKWU: The composition of bones of mice receiving estrogens and androgens, Endocrinology, 1940, xxvi, 61-67. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Received for publication January 20, 1942.From the Vascular Clinic, Department of Medicine, New York Post-Graduate Medical School and Hospital, Columbia University. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPrimary hypertrophic osteoarthropathyOsteosklerose und HyperostosePachydermoperiostosis (Idiopathic Clubbing and Periostosis)Pachydermoperiostosis 1 December 1943Volume 19, Issue 6Page: 1018-1028KeywordsBoneHospital medicineLesionsVascular medicine ePublished: 1 December 2008 Issue Published: 1 December 1943 PDF downloadLoading ...