Estrogen Receptor Activity in a Case of Hodgkin's Disease
Authors: JAMES J. STARK
Journal: Annals of Internal Medicine (1981)

Brief Reports1 August 1981Estrogen Receptor Activity in a Case of Hodgkin's DiseaseJAMES J. STARK, M.D., JOHN W. LLOYD, Ph.D., PAUL F. SCHELLHAMMER, M.D.JAMES J. STARK, M.D.Search for more papers by this author, JOHN W. LLOYD, Ph.D.Search for more papers by this author, PAUL F. SCHELLHAMMER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-95-2-186 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe discovery by Jensen and colleagues (1) and others (2) of the presence of estrogen receptors in human breast cancers and the subsequent correlation of the presence of hormone receptors and response to therapy have had profound effects on the modern management of patients with advanced cancer of the breast. Estrogen receptor activity has also been identified in normal liver, endometrium, and pancreas; in neoplasms other than those of breast, including adenocarcinoma of endometrium, colon, and ovary; and in malignant melanoma (3). To date these observations have been of only modest therapeutic significance. Presented here is the case of a...References1. JENSENDESOMBREJUNGBLEST EEP. Estrogen receptors in hormone-responsive tissues and tumors. In: Endogenous Factors influencing Host-Tumor Balance. WISSLER, RW, DAO, TL, WOOD, S JR, eds. Chicago: University of Chicago Press; 1967:15-30. Google Scholar2. TERENIUS L. Selective retention of estrogen isomers in estrogen-dependent breast tumors of rats demonstrated by in vitro methods. Cancer Res. 1968;28:328-37. MedlineGoogle Scholar3. MCCLENDONAPPLEBYCLAUDONDONEGANDECOSSE JDDWJ. Colonic neoplasms: tissue estrogen receptor and carcino embryonic antigen arch. Surgery, 1977;112:240-1. Google Scholar4. KORENMANDUKES SB. Specific estrogen binding by the cytoplasm of human breast carcinoma. Clin Endocrinol Metab. 1970;30:639-45. CrossrefGoogle Scholar5. JENSENDESOMBRE EE. Estrogen receptor interaction. Science. 1973;182:126-34. CrossrefMedlineGoogle Scholar6. BLACKARDBYARJORDON CDW. Orchiectomy for advanced prostatic carcinoma: a reevaluation. Urology. 1973;1:553-60. CrossrefMedlineGoogle Scholar7. LIPPMANALLEGRA MJ. Receptors in breast cancer, in current concepts in cancer. N Engl J Med. 1978;299:930-3. CrossrefMedlineGoogle Scholar8. KIANGKENNEDY DB. Estrogen receptor assay in the differential diagnosis of adenocarcinomas. JAMA. 1977;238:32-4. CrossrefMedlineGoogle Scholar9. TASHIMA C. Estrogen receptor assay. JAMA. 1977;238:2263. Letter. CrossrefMedlineGoogle Scholar10. ROSENBERGKAPLANGLATSTEINPORTLOCK SHEC. Combined modality therapy of Hodgkins disease. Cancer. 1978;42:991-1000. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Eastern Virginia Medical School Norfolk, Virginia. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byImmunohistochemical Characterization of Estrogen and Progesterone Receptors in Lymphoma of HorsesSex Steroid Receptors in Hodgkin's DiseaseImmunocytochemical identification of nuclear estrogen-receptors in human acute myeloid leukemiaPrimary breast lymphoma: An immunohistologic study of 20 new casesOestrogen receptor (ER) analysis in B-cell chronic lymphocytic leukemia: Correlation of biochemical and immunocytochemical methodsTamoxifen in the Treatment of Refractory LymphomaCharacterization of a specific androgen receptor in non-Hodgkin's lymphoma cellsThe pharmacology and clinical uses of tamoxifenCoexistent breast and vaginal granulocytic sarcomaEstrogen Receptors in Various TissuesDAVID T. KIANG, M.D., PH.D.Estrogen Receptors and Lymphocytic LymphomaDENNIS MORGAN, M.D.Estrogen Receptor Activity in Hodgkin's DiseasePARTHASARATHY NARASIMHAN, M.D. 1 August 1981Volume 95, Issue 2Page: 186-187KeywordsBreast cancerColonEndometriumEstrogensHodgkin lymphomaHormonesLiverMelanomaOvariesPancreas Issue Published: 1 August 1981 PDF downloadLoading ...