THE SULFONAMIDE THERAPY OF STAPHYLOCOCCAL SEPTICEMIA
Authors: Robert G. Torrey, L. A. Julianelle, H. G. Mcnamee
Journal: Annals of Internal Medicine (1941)

Article1 September 1941THE SULFONAMIDE THERAPY OF STAPHYLOCOCCAL SEPTICEMIAROBERT G. TORREY, F.A.C.P., L. A. JULIANELLE, H. G. MCNAMEEROBERT G. TORREY, F.A.C.P.Search for more papers by this author, L. A. JULIANELLESearch for more papers by this author, H. G. MCNAMEESearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-15-3-431 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptINTRODUCTIONThe history of medicine probably contains no parallel example of the generalized acceptance and popularity of a treatment as that of the sulfonamide derivatives. While there can be little question of the efficacy of these drugs in certain infections, it is becoming increasingly apparent from the slowly accumulating reports of more conservative observers, that the exaggerated faith in their panaceal capacities does not appear to be justified, as, indeed, recent critical reviews illustrate.1-3Among the different communications devoted to sulfonamide therapy, a number of scattered reports have dealt with the successful treatment of staphylococcal septicemia. Consisting to a great...References1. HEUBNER W: Chemotherapie von Infektionskrankheiten, Klin. Wchnschr., 1940, xix, 265; 289. CrossrefGoogle Scholar2. KOLMER JA: Progress in chemotherapy of bacterial and other diseases, with special reference to prontosils, sulfanilamide, and sulfapyridine, Arch. Int. Med., 1940, lxv, 671-743. CrossrefGoogle Scholar3. REIMANN HA: Infectious diseases: A review of significant publications in 1939-1940, ibid., 1940, lxvi, 478-525. Google Scholar4. JULIANELLE LA: Observation on the specific treatment (Type A antiserum) of staphylococcal septicemia, ANN. INT. MED., 1939, xiii, 308-316. Google Scholar5. FOERSTER : Sepsis in Anschluss an ausgedehnte Periportitis: Heilung durch Streptozon, Zentralbl. Haut. u. Geschlechtskr., 1933, xlv, 549. Cited by Kolmer.2 Google Scholar6. MITCHELL A: Treatment of acute osteomyelitis by Uleron, Brit. Med. Jr., 1938, ii, 1200-1. CrossrefGoogle Scholar7. COLEBROOKKENNY LM: Treatment of human puerperal infection and of experimental infection in mice with prontosil, Lancet, 1936, i, 1279-1286. CrossrefGoogle Scholar8. MENDELL TH: Staphylococcic septicemia, Arch. Int. Med., 1939, lxiii, 1068-1083. CrossrefGoogle Scholar9. THORNHILLSWARTREEL WAHAC: Sulfanilamide in staphylococcal septicemia, Jr. Am. Med. Assoc., 1939, cxiii, 1638-1639. Google Scholar10. BLAKEHAVILAND FGJW: Sulfapyridine in pneumococcal, streptococcal, and staphylococcal infections, Trans. Assoc. Am. Phys., 1939, liv, 130-148. Google Scholar11. FENTONHODGKISS WJF: Staphylococcal septicemia treated with M and B 693, Lancet, 1938, ii, 667-668. CrossrefGoogle Scholar12. GALEWSKISTANNUS SHS: Septicemia due to Staphylococcus albus and treated with M and B 693, Lancet, 1939, ii, 1067-1068. CrossrefGoogle Scholar13. GOLDBERGSACHS SLA: Sulfapyridine in the treatment of Staphylococcus aureus bacteremia, Jr. Am. Med. Assoc., 1939, cxiii, 1639-1641. Google Scholar14. HARTMANNBARNETTPERLEYRUHOFF AFHLAMMB: Present status of therapy with sulfanilamide and sulfapyridine, Jr. Missouri State Med. Assoc., 1940, xxxvii, 41-54. Google Scholar15. LONG PN: Sulfapyridine, Jr. Am. Med. Assoc., 1939, cxii, 538-539. CrossrefGoogle Scholar16. MARTINBRYAN WBR: Treatment of severe Staphylococcus infections with sulfapyridine or its sodium salt, South. Med. Jr., 1940, xxxiii, 1039-1044. CrossrefGoogle Scholar17. O'BRIENMCCARTHY EJCJ: Staphylococcal septicemia treated with M and B 693, Lancet, 1938, ii, 1232-1234. CrossrefGoogle Scholar18. SPINKHANSENPAINE WWAEJR: Staphylococcic bacteremia. Treatment with sulfapyridine and sulfathiazole, Arch. Int. Med., 1941, lxvii, 25-35. CrossrefGoogle Scholar19. WADE HJ: Staphylococcal septicemia treated with M and B 693, Lancet, 1939, i, 756. CrossrefGoogle Scholar20. CARROLLKAPPELJONESGALLAGHERDIROCCO GLLFWFW: Sulfamethylthiazole. A report of its clinical use in Staphylococcus septicemia with apparent success. Report of animal experiments, South. Med. Jr., 1940, xxxiii, 83-87. CrossrefGoogle Scholar21. HARTMANN AF: Personal communication. Google Scholar22. HERRELLBROWN WEAE: The clinical use of sulfamethylthiazole in infections caused by Staphylococcus aureus. Preliminary report, Proc. Staff Meet. Mayo Clin., 1939, xiv, 753-758. Google Scholar23. WEISMANRUSSELL DH: The treatment of acute staphylococcic infection with sulfamethylthiazole, Jr. Pediat., 1940, xvii, 31-37. CrossrefGoogle Scholar24. CAREY BW: Use of sulfanilamide and related compounds in diseases of infancy and childhood, Jr. Am. Med. Assoc., 1940, cxv, 924-929. CrossrefGoogle Scholar25. FITCH TS: Sulfathiazole in Staphylococcus aureus. Epidermal abscess with septicemia and pyemia, Arch. Pediat., 1940, lvii, 119-124. Google Scholar26. KELIHERCARLAN TFSA: Treatment of staphylococcal septicemia with sulfamethylthiazole. Report of a case with recovery, Med. Ann. District of Columbia, 1940, ix, 78-80. Google Scholar27. RAMMELKAMPKEEFER CHCS: Sulfathiazole therapy of Staphylococcus aureus bacteremia, New Eng. Jr. Med., 1940, ccxxiii, 877-885. CrossrefGoogle Scholar28. SCOTT GA: Effect of sulfonamides on blood-serum, Lancet, 1939, ii, 244-246. CrossrefGoogle Scholar29. STIRLING WC: Sulfathiazole: Two cases of septicemia with recovery, Jr. Am. Med. Assoc., 1940, cxv, 118-120. CrossrefGoogle Scholar30. ABRAMSONFLACKS AWB: Staphylococcal septicemia complicating carbuncle of face. Recoveries after treatment with M and B 692, Lancet, 1939, ii, 1065-1067. CrossrefGoogle Scholar31. HERRELLBROWN WEAE: Treatment of septicemia, Jr. Am. Med. Assoc., 1941, cxvi, 179-183. CrossrefGoogle Scholar32. JULIANELLE LA: Determination of staphylococcal types by fermentation of mannite, Proc. Soc. Exper. Biol. and Med., 1937, xxxvi, 117-119. CrossrefGoogle Scholar33. JULIANELLEWIEGHARD LACW: Immunological specificity of Staphylococci, Jr. Exper. Med., 1935, lxii, 23-30; also 31-37. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication April 9, 1941.From The Department of Medicine, Women's Medical College, Philadelphia, the Department of Ophthalmology, Washington University School of Medicine, St. Louis, and the Philadelphia General Hospital, Philadelphia.A grant from the Commonwealth Fund of New York (to L. A. J.) aided in the conduct of this study.†Dr. Robert G. Torrey died before this manuscript was completed, so that the responsibility for the opinions expressed must fall entirely upon the junior authors. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byStaphylococcus aureus septicemia and pericarditis treated with penicillin 1 September 1941Volume 15, Issue 3Page: 431-445KeywordsDrug therapyFallsHistory of medicineHospital medicineOphthalmologySepsisStaphylococcal infectionSulfonamide ePublished: 1 December 2008 Issue Published: 1 September 1941 PDF downloadLoading ...