A Comparison of Digitalis Intoxication in Two Separate Periods
Authors: MORTON H. DUBNOW
Journal: Annals of Internal Medicine (1965)

Article1 May 1965A Comparison of Digitalis Intoxication in Two Separate PeriodsMORTON H. DUBNOW, M.D., HOWARD B. BURCHELL, M.D., PH.D.MORTON H. DUBNOW, M.D., HOWARD B. BURCHELL, M.D., PH.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-62-5-956 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn an account of the foxglove in 1785, Withering (1) stated, "The foxglove when given in very large and quickly-repeated doses, occasions sickness, vomiting, purging, giddiness, confused vision, objects appearing green or yellow; increased secretion of urine, with frequent motions to part with it, and sometimes inability to retain it; slow pulse, even as slow as 35 in a minute, cold sweats, convulsions, syncope, death." Although this classic description was given almost two centuries ago, digitalis intoxication remains a not infrequent clinical problem. Some authors (2-4) have emphasized a changing picture of digitalis intoxication and have especially noted a greater...References1. WITHERING W: An Account of the Foxglove, C. G. J. and J. Robinson, Paternoster-Row, London, 1785, pp. 10, 184. Google Scholar2. VON CAPELLERCOPELANDSTERN DGDTN: Digitalis intoxication: a clinical report of 148 cases. Ann. Intern. Med. 50: 869, 1959. LinkGoogle Scholar3. CROUCHHERRMANNHEJTMANCIK RBGRMR: Digitalis intoxication. Texas J. Med. 52: 714, 1956. MedlineGoogle Scholar4. SHRAGER MW: Digitalis intoxication: a review and report of forty cases, with emphasis on etiology. Arch. Intern. Med. (Chicago) 100: 881, 1957. CrossrefGoogle Scholar5. BATTERMANDEGRAFFROSE RCACOA: The therapeutic range of gitalin (amorphous) compared with other digitalis preparations. Circulation 5: 201, 1952. CrossrefMedlineGoogle Scholar6. 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ENSELBERGSIMMONSMINTZ CDHGAA: The effects of potassium upon the heart, with special reference to the possibility of treatment of toxic arrhythmias due to digitalis. Amer. Heart. J. 39: 713, 1950. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Rochester, MinnesotaFrom the Mayo Clinic and Mayo Foundation, Rochester, Minnesota.Requests for reprints should be addressed to Mayo Clinic, Rochester, Minn. 55902. 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KASTOR, M.D., PETER M. YURCHAK, M.D., F.A.C.P.Digitalis-induced arrhythmias and their management 1 May 1965Volume 62, Issue 5Page: 956-965KeywordsAttentionConvulsionsElectrocardiographyHeart rateIntoxicationSweatSyncopeUrineVisionVomiting Issue Published: 1 May 1965 PDF downloadLoading ...