APNEA DUE TO BENADRYL
Authors: Jerome I. Brody, James L. Tobin
Journal: Annals of Internal Medicine (1957)

Case Reports1 July 1957APNEA DUE TO BENADRYLJEROME I. BRODY, JAMES L. TOBINJEROME I. BRODYSearch for more papers by this author, JAMES L. TOBINSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-47-1-172 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe antihistaminics have become important therapeutically in today's medical practice. As a matter of fact, so common has their use become that their safety and lack of toxicity are no longer questioned to any great extent. The reality remains, however, that these agents are not without their side-effects and toxic reactions, many of which are serious, and physicians now prescribe this type of medication with little or no consideration of consequences. We therefore wish to report a toxic reaction to β-dimethylaminoethyl benzhydryl ether hydrochloride (Benadryl) which, as far as we know, has not previously been described in the clinical literature....Bibliography1. Aaron FE: Acute diphenhydramine hydrochloride poisoning, Brit. M. J. 2: 24, 1953. CrossrefMedlineGoogle Scholar2. Beckman H: Pharmacology in clinical practice, 1952, W. B. Saunders Co., Philadelphia. Google Scholar3. BlackmanHayes NSJC: Fatality with Benadryl therapy, J. Allergy 19: 390, 1948. CrossrefMedlineGoogle Scholar4. Borman MC: Danger of self-medication and large doses of Benadryl, J. A. M. A. 133: 394, 1947. CrossrefMedlineGoogle Scholar5. CarlisleCrescitelli EMF: Selective inhibition of brain respiration by Benadryl, Science 112: 272-273, 1950. CrossrefMedlineGoogle Scholar6. ChitwoodMoore WRCD: Case report of Benadryl intoxication, Virginia M. Monthly 8: 132, 1951. Google Scholar7. DavisHunt JHHH: Accidental poisoning due to Benadryl, J. Pediat. 34: 358, 1949. 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A. M. A. 145: 277-282, 1951. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication September 24, 1956.From the Department of Medicine, 3650th USAF Hospital, Sampson Air Force Base, N. Y.Requests for reprints should be addressed to Jerome I. Brody, M.D., The Graduate Hospital, University of Pennsylvania, Nineteenth and Lombard Streets, Philadelphia, Pennsylvania. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byVERATRUM ALKALOIDS AND OTHER DRUGS STIMULATING CHEMOREFLEXES 1 July 1957Volume 47, Issue 1Page: 172-177KeywordsApneaHospital medicineIntoxicationRespirationSafetyToxicity ePublished: 1 December 2008 Issue Published: 1 July 1957 PDF downloadLoading ...