ERYTHEMA NODOSUM: THE POSSIBLE SIGNIFICANCE OF ASSOCIATED PULMONARY HILAR ADENOPATHY
Authors: C C JOHNSON, N O HANSON, C A GOOD
Journal: Annals of Internal Medicine (1951)

Article1 April 1951ERYTHEMA NODOSUM: THE POSSIBLE SIGNIFICANCE OF ASSOCIATED PULMONARY HILAR ADENOPATHYC. CLIFFORD JOHNSON, M.D., NORBERT O. HANSON, M.D., C. ALLEN GOOD, M.D.C. CLIFFORD JOHNSON, M.D.Search for more papers by this author, NORBERT O. HANSON, M.D.Search for more papers by this author, C. ALLEN GOOD, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-34-4-983 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptErythema nodosum has been described by Spink1as "a nonspecific inflammatory reaction of the skin to a variety of bacterial, toxic and chemical agents." It is characterized, according to Spink, as an acute febrile illness with painful, nodular, erythematous lesions on shins and forearms and by joint pains and malaise. Hilar adenopathy is associated with the above signs in some cases but has not been recognized generally as an accompaniment of the condition. Three cases of erythema nodosum in which hilar adenopathy was a feature were encountered at the Mayo Clinic in a period of four months, and in each...Bibliography1. Spink WW: Pathogenesis of erythema nodosum, Arch. Int. Med. 59: 65-81, 1937. CrossrefGoogle Scholar2. Keil H: Erythema nodosum, J. A. M. A. 112: 763, 1939. CrossrefGoogle Scholar3. Gray WD: Erythema nodosum and tuberculosis, Brit. M. J. 2: 286-287, 1945. CrossrefMedlineGoogle Scholar4. Wallgren A: Erythema nodosum and pulmonary tuberculosis, Lancet 1: 359-363, 1938. CrossrefGoogle Scholar5. Wallgren A: Rheumatic erythema nodosum, Am. J. Dis. Child. 55: 897-912, 1938. Google Scholar6. Wallgren A: Tubercle bacilli in children with erythema nodosum, Am. J. Dis. Child. 41: 816-822, 1931. CrossrefGoogle Scholar7. 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Google Scholar28. PoppelMelamed MHAM: Erythema nodosum, New England J. Med. 227: 325-330, 1942. CrossrefGoogle Scholar29. Keil H: Relation of erythema nodosum and rheumatic fever; a critical survey, Ann. Int. Med. 10: 1686-1707, 1937. LinkGoogle Scholar30. Carter RA: Pulmonary mycotic infections, Radiology 26: 551-562, 1936. CrossrefGoogle Scholar31. Bargen JA: Complications and sequelae of chronic ulcerative colitis, Ann. Int. Med. 3: 335-352, 1929. LinkGoogle Scholar32. Bonnet WL: Roentgen findings in erythema nodosum, Radiology 47: 175-177, 1946. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Rochester, Minnesota*Received for publication August 30, 1949.From the Mayo Foundation and the Division of Medicine and the Section on Roentgenology of the Mayo Clinic, Rochester, Minnesota. 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