THE SIGNIFICANCE OF NONBACTERIAL THROMBOTIC ENDOCARDITIS: AN AUTOPSY AND CLINICAL STUDY OF 78 CASES
Authors: R A MACDONALD, S L ROBBINS
Journal: Annals of Internal Medicine (1957)

Article1 February 1957THE SIGNIFICANCE OF NONBACTERIAL THROMBOTIC ENDOCARDITIS: AN AUTOPSY AND CLINICAL STUDY OF 78 CASESRICHARD A. MACDONALD, M.D., STANLEY L. ROBBINS, M.D.RICHARD A. MACDONALD, M.D.Search for more papers by this author, STANLEY L. ROBBINS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-46-2-255 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe purpose of this paper is to call attention to the relatively unappreciated fact that nonbacterial thrombotic endocarditis has a clinical as well as a pathologic significance. Previous workers have studied this type of endocarditis from the standpoint of its histologic features, so that up to the present time there have been no studies correlating clinical and autopsy findings. From a review at the Mallory Institute of Pathology there is evidence that in a certain number of cases emboli may arise from the valvular vegetations and cause premortem infarction of organs. These infarctions in some cases contribute to death, and...Bibliography1. Libman E: Characterization of various forms of endocarditis, J. A. M. A. 80: 813-818, 1923. CrossrefGoogle Scholar2. Libman E: The varieties of endocarditis and their clinical significance, Tr. A. Am. Physicians 53: 345-351, 1938. Google Scholar3. GrossFriedberg LCK: Nonbacterial thrombotic endocarditis. Classification and general description, Arch. Int. Med. 58: 620-640, 1936. CrossrefGoogle Scholar4. AllenSirota ACJH: The morphogenesis and significance of degenerative verrucal endocardiosis (terminal endocarditis, endocarditis simplex, nonbacterial thrombotic endocarditis), Am. J. Path. 20: 1025-1056, 1944. MedlineGoogle Scholar5. 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D. AMROMIN, M.D., S. K. WANG, M.D.The PancreasTheory and Practice in Acute Venous ThrombosisPulmonary intra-arteriolar thrombi associated with cancerCase 43211 1 February 1957Volume 46, Issue 2Page: 255-273KeywordsAutopsyEndocarditisInfarctionThrombosis ePublished: 1 December 2008 Issue Published: 1 February 1957 PDF downloadLoading ...