THE USE OF RADIOACTIVE PHOSPHORUS IN THE THERAPY OF LEUKEMIA, POLYCYTHEMIA VERA AND LYMPHOMAS: A REPORT OF 10 YEARS' EXPERIENCE
Authors: R B CHODOS, J F ROSS
Journal: Annals of Internal Medicine (1958)

Article1 May 1958THE USE OF RADIOACTIVE PHOSPHORUS IN THE THERAPY OF LEUKEMIA, POLYCYTHEMIA VERA AND LYMPHOMAS: A REPORT OF 10 YEARS' EXPERIENCEROBERT B. CHODOS, M.D., F.A.C.P., JOSEPH F. ROSS, M.D., F.A.C.P.ROBERT B. CHODOS, M.D., F.A.C.P.Search for more papers by this author, JOSEPH F. ROSS, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-48-5-956 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptRadioactive phosphorus is now generally accepted as an effective therapeutic agent for chronic leukemia and polycythemia vera. There is some disagreement, however, as to how it should be used in the treatment of patients with chronic leukemia. In most clinics, therapy of chronic leukemia with radiophosphorus has been initiated by the "fractional" or "saturation" methods of Low-Beer et al.16Subsequent dosage has depended upon the clinical and hematologic response of the individual patient,2, 7, 10, 11with additional radiophosphorus being administered only when there was evidence of progression of the disease. The resulting length of survival has been approximately that...Bibliography1. LawrenceScottTuttle JHKGLW: Studies on leukemia with the aid of radioactive phosphorus, Internat. Clin. 3: 33, 1939. Google Scholar2. ReinhardMooreBierbaumMoore EHCVOSS: Radioactive phosphorus as a therapeutic agent. A review of the literature and analysis of the results of treatment of 155 patients with various blood dyscrasias, lymphomas, and other malignant neoplastic diseases, J. Lab. and Clin. Med. 31: 107, 1946. MedlineGoogle Scholar3. Erf LA: Primary polycythemia: remissions induced by therapy with radiophosphorus, Blood 1: 202, 1946. 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Stroebel CF: Current status of radiophosphorus therapy, Proc. Staff Meet., Mayo Clin. 29: 1, 1954. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication January 28, 1957.From the Robert Dawson Evans Memorial and Massachusetts Memorial Hospitals, and the Department of Medicine, Boston University School of Medicine, Boston.A portion of this work was supported by a grant from the Atomic Energy Commission to the Massachusetts Memorial Hospitals.Requests for reprints should be addressed to Robert B. Chodos, M.D., Veterans Administration Hospital, Syracuse 10, N. Y. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDie chronische lymphatische LeukämieDie Therapie der Polycythaemia rubra vera Vaquez-OslerDie Therapie der Polycythaemia rubra vera Vaquez-OslerTransitions Among the Myeloproliferative DisordersROBERT M. GLASSER, M.D., RICHARD I. WALKER, M.D.MANIFOLD CHROMOSOME ABNORMALITIES IN LEUKÆMIARadioactive isotopes in radiotherapy (Part Two)The Treatment of Leukemic Priapism with A-139Leukemia: Some Present-Day Problems 1 May 1958Volume 48, Issue 5Page: 956-977KeywordsHospital medicineLymphocytic leukemiaLymphomaMultiple myelomaPatientsPhosphorusPolycythemiaPolycythemia vera ePublished: 1 December 2008 Issue Published: 1 May 1958 PDF downloadLoading ...