EXPERIENCES IN THE DIAGNOSIS AND ANTIBIOTIC THERAPY OF AMEBIASIS: AN ANALYSIS OF 50 CASES
Authors: Nelson J. Weiser, Eugene Spiotta, Pierre Ekman
Journal: Annals of Internal Medicine (1953)

Article1 May 1953EXPERIENCES IN THE DIAGNOSIS AND ANTIBIOTIC THERAPY OF AMEBIASIS: AN ANALYSIS OF 50 CASESNELSON J. WEISER, EUGENE SPIOTTA, PIERRE EKMANNELSON J. WEISERSearch for more papers by this author, EUGENE SPIOTTASearch for more papers by this author, PIERRE EKMANSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-38-5-1002 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSTATEMENT OF PURPOSEAt an Army installation drawing much of its patient population from veterans of the Korean war, we have had the opportunity to observe 50 patients with amebiasis. These patients demonstrate the wide variations in the manifestations of this disease, including some which have seldom been reported. They illustrate the difficulties encountered in diagnosis and the frequency with which patients with amebiasis are thought to have a surgical abdominal emergency. We have had an almost unique opportunity for prolonged, close and intensive observation of these patients, one seldom found in private practice, and we have had therapeutic results...Bibliography1. Most H: Recent advances in the therapy of the more common protozoan and helminthic infections of man, Bull. New York Acad. Med. 25: 717-740 (Nov.) 1949. MedlineGoogle Scholar2. AndersonJohnstonePackerYoungCallisonHamblyAndersonReed HHHGHJDMKASJVRK: Incidence and control of amebiasis and other protozoan infections in a Memphis hospital, Am. J. Trop. Med. 28: 373-382, 1948. CrossrefMedlineGoogle Scholar3. Callender GR: Dysenteries and diarrheas—their importance in military service, War Med. 4: 459-464 (Nov.) 1943. Google Scholar4. McVayLairdSprunt LVRLDH: A preliminary report of the successful treatment of amebiasis with aureomycin, Science 109: 590, 1949. CrossrefMedlineGoogle Scholar5. Hargreaves WH: The treatment of amebiasis with special reference to chronic amebic dysentery, Quart. J. Med. 15: 1-21, 1946. CrossrefMedlineGoogle Scholar6. ZavolaHamilton DCHE: Recognition and treatment of hepatic amebiasis, Ann. Int. Med. 36: 110-125 (Jan.) 1952. LinkGoogle Scholar7. Sandler R: Chronic involvement of the liver in intestinal amebiasis, Am. J. Digest. Dis. 18: 29 (Jan.) 1951. CrossrefMedlineGoogle Scholar8. Payne AM: Amebic dysentery in Eastern India, Lancet : 1: 206-209, 1945. CrossrefGoogle Scholar9. Palmer RB: Histopathology of the liver in amebiasis, Arch. Path. 25: 327, 1938. Google Scholar10. SodemanLewis WBO: Amebic hepatitis, Am. J. Trop. Med. 25: 35-39 (Jan.) 1945. CrossrefGoogle Scholar11. SodemanLewis WBO: Amebic hepatitis: report of 33 cases, J. A. M. A. 129: 99-104 (Sept. 8) 1945. CrossrefGoogle Scholar12. Wright WH: The public health status of amebiasis in the United States as revealed by available statistics, Am. J. Trop. Med. 30: 123, 1950. CrossrefMedlineGoogle Scholar13. Hall W: Treatment of chronic human amebiasis with aureomycin, New England J. Med. 244:495 (Apr. 5) 1951. CrossrefMedlineGoogle Scholar14. Hoekenga MT: Comparison of aureomycin and carbarsone in the treatment of intestinal amebiasis, Am. J. Trop. Med. 31: 423, 1951. CrossrefMedlineGoogle Scholar15. Lane R: Treatment of hepatic amebiasis with chloroquine, J. Trop. Med. 54: 198 (Oct.) 1951. Google Scholar16. Conan NJ: Treatment of amebic hepatitis with chloroquine, Am. J. Med. 6: 309, 1949. CrossrefMedlineGoogle Scholar17. Sodeman WA: Clinical picture of hepatic amebiasis, Am. J. Trop. Med. 30: 141, 1950. CrossrefMedlineGoogle Scholar18. HusseyBrown KLWH: The complement fixation test for hepatic amebiasis, Am. J. Trop. Med. 30: 147, 1950. CrossrefMedlineGoogle Scholar19. TobieMostReardonBozicevich JEHLVJ: Laboratory results of the efficacy of terramycin, aureomycin, and bacitracin in the treatment of asymptomatic amebiasis, Am. J. Trop. Med. 31: 414, 1951. CrossrefMedlineGoogle Scholar20. Calero C: Aureomycin in the treatment of intestinal amebiasis, Am. J. Trop. Med. 31: 566 (Sept.) 1951. CrossrefMedlineGoogle Scholar21. Bozicevich J: Discussion of,18 Am. J. Trop. Med. 30: 156, 1950. Google Scholar22. SpingarEdelman CLMH: The effect of aureomycin hydrochloride on the growth of E. histolytica in vitro, Am. J. Trop. Med. 31: 206 (Mar.) 1951. CrossrefMedlineGoogle Scholar23. Dennis EW: Discussion of chemotherapy of amebiasis in amebiasis panel, Am. J. Trop. Med. 30: 159, 1950. CrossrefMedlineGoogle Scholar24. BradinHansen JLEL: Indirect in vitro action of antibiotics: comparison with accepted amebacides, Am. J. Trop. Med. 30: 27-41, 1950. CrossrefMedlineGoogle Scholar25. Ibid., pp. 193-201. Google Scholar26. AndersonAnderson HHJ: Amebiasis panel; amebiasis in macaques, Am. J. Trop. Med. 30: 193-201, 1950. CrossrefMedlineGoogle Scholar27. NushanMiller HB: Ameboma of the transverse colon, Ann. Int. Med. 37: 372, 1952. LinkGoogle Scholar28. Mostvan Assendelft HF: Terramycin in the treatment of amebiasis; laboratory and clinical observations, Ann. New York Acad. Sc. 53: 427, 1950. CrossrefMedlineGoogle Scholar29. ChangChenChou HCKCSK: Further observations on the diagnosis of amebic dysentery, Chinese M. J. 50: 17-26 (Jan.) 1936. Google Scholar30. OchsnerDeBakey AM: Surgical amebiasis, The New International Clinics: Vol. I, New Series Five, 68-99 (Mar.) 1942. Google Scholar31. Hines LE: A form of polypoid colitis as a late stage of amebic dysentery, J. A. M. A. 81: 12, 1923. CrossrefGoogle Scholar32. Anderson HH: Amebiasis and pseudopolyposis of the colon, J. A. M. A. 107: 2121, 1936. CrossrefGoogle Scholar33. SodemanBeaver WAPC: A study of the therapeutic effects of some amebacidal drugs, Am. J. Med. 12: 440-446, 1952. CrossrefMedlineGoogle Scholar34. Conan NJ: The treatment of amebic hepatitis with chloroquine, Bull. New York Acad. Med. 24: 545-546, 1948. MedlineGoogle Scholar35. Palmer RB: Military amebiasis, Am. J. Trop. Med. 26: 543, 1946. CrossrefMedlineGoogle Scholar36. Conan NJ: Chloroquine in amebiasis, Am. J. Trop. Med. 28: 107-110, 1948. CrossrefMedlineGoogle Scholar37. Hughes JD: Treatment of amebiasis with aureomycin; report of 38 cases, J. A. M. A. 142: 1052-1054, 1950. CrossrefGoogle Scholar38. WilmotArmstrong AJTG: Treatment of amebic dysentery in Bantu African, Tr. Roy. Soc. Trop. Med. and Hyg. 42: 597-604 (May) 1949. CrossrefMedlineGoogle Scholar39. D'Antoni JS: Amebiasis: recent concepts of its prevalence, symptomatology, diagnosis and treatment, The New International Clinics: Vol. I, New Series Five, p. 100 (Mar.) 1942. Google Scholar40. ReadHushan WAH: Amebic granuloma simulating carcinoma, Gastroenterology 15: 771-779 (Aug.) 1950. CrossrefMedlineGoogle Scholar41. BerberianDennisPipkin DAEWCA: The effectiveness of Milibis in amebiasis, Am. J. Trop. Med. 30: 613, 1950. CrossrefMedlineGoogle Scholar42. Ibid., pp. 193-201, 1950. Google Scholar43. SenecaHenderson HE: Combined antiamebic and antibacterial treatment of intestinal amebiasis, Am. Pract. and Digest Treat. 1: 960 (Sept.) 1950. MedlineGoogle Scholar44. Radke R: Incidence of amebiasis in Korean veterans, U. S. Armed Forces M. J. 3: 323 (Feb.) 1952. MedlineGoogle Scholar45. Klatskin G: Amebiasis of the liver; classification, diagnosis, and treatment, Ann. Int. Med. 25: 601, 1946. LinkGoogle Scholar46. OchsnerDeBakey AM: Amebic hepatitis and hepatic abscess, Surgery 13: 460, 1943. Google Scholar47. Radke R: Amebiasis with hepatic abscess and pleuropulmonary involvement, U. S. Armed Forces M. J. 2: 437-444 (March) 1951. MedlineGoogle Scholar48. McVayLairdSprunt LVRLDH: The treatment of amebiasis with aureomycin, South. M. J. 43: 308-313, 1950. CrossrefGoogle Scholar49. Meleney JE: The pathology of amebiasis, J. A. M. A. 103: 1213, 1934. CrossrefGoogle Scholar50. Rogers L: Amebic liver abscess, Lancet 1: 463, 1922. CrossrefGoogle Scholar51. Munk J: X-ray appearance in amebic hepatitis, Brit. J. Radiol. 17: 48, 1944. CrossrefGoogle Scholar52. Pancoast HK: The roentgenologic diagnosis of liver abscess with or without subdiaphragmatic abscess, Am. J. Roentgenol. 16: 303, 1926. Google Scholar53. OchsnerDeBakey AM: Amebic hepatitis and hepatic abscess, Surgery 13: 612, 1943. Google Scholar54. SodemanLewis WABO: Amebic hepatitis, Am. J. Trop. Med. 25: 35, 1945. CrossrefGoogle Scholar55. Craig CF: Amebiasis and the complement fixation test, U. S. Armed Forces M. J. 1: 1337-1342, 1950. MedlineGoogle Scholar56. HusseyBrown KLHW: The complement fixation test for hepatic amebiasis, Am. J. Trop. Med. 30: 147-157, 1950. CrossrefMedlineGoogle Scholar57. JacksonHaightKassWomackGockeFinland GGTHEHCRTMM: Terramycin therapy of pneumonia: clinical and bacteriologic studies in 91 cases, Ann. Int. Med. 35: 1175-1202 (Dec.) 1951. LinkGoogle Scholar58. Faust EL: The prevalence of amebiasis in the Western Hemisphere, Am. J. Trop. Med. 22: 93, 1942. CrossrefGoogle Scholar59. JacobsWallaceDiamond LFGLS: Survey of intestinal parasites in soldiers being separated from service, Bull. U. S. Army M. Dept. 6: 259-262 (Sept.) 1946. MedlineGoogle Scholar60. RogersMegaw LJW: Tropical medicine, 4th Ed., J. & A. Churchill, Ltd., London, 1942. Google Scholar61. Weselmann H: Vorkommen von Entamoeba histolytica im Duodenum, Deutsche tropenmed. Ztschr. 46: 457, 1942. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication November 28, 1952.From the Medical Service, U. S. Army Hospital, Fort Campbell, Kentucky. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byLiver Function and Morphology in “q” Fever 1 May 1953Volume 38, Issue 5Page: 1002-1026KeywordsAmebiasisAntibioticsMedical services ePublished: 1 December 2008 Issue Published: 1 May 1953 PDF downloadLoading ...