LIVER FUNCTION IN MENSTRUATION
Authors: Robert Heilig, N. L. Kantiengar
Journal: Annals of Internal Medicine (1942)

Article1 March 1942LIVER FUNCTION IN MENSTRUATIONROBERT HEILIG, M.D., N. L. KANTIENGAR, B.SC., M.B.B.S.ROBERT HEILIG, M.D.Search for more papers by this author, N. L. KANTIENGAR, B.SC., M.B.B.S.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-16-3-538 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptWhile studying the excretion of hippuric acid in pregnancy Hirsheimer (1935) has shown that elimination of hippuric acid after administration of sodium benzoate is diminished towards the termination of normal and toxemic pregnancies, results confirmed later by other authors. The present investigation was undertaken to find whether the hepatic function during the menstrual period varies consistently from that recorded in the interval.For this purpose we used Quick's test, based on the ability of the liver to detoxify benzoic acid by conjugation with glycine to form hippuric acid. First devised by Quick (1931), this test has been used sufficiently to...Bibliography1. ADLERSBERGMINIBECK DH: Zur Auswertung der Leberfunktionsproben im Tierversuch (Galaktoseprobe, Wasserversuch, Hippursäuresynthese bei der Phosphor und Tetrachlorkohlenstoffvergiftung), Ztschr. f. d. ges. exper. Med., 1936, xcviii, 185-200. CrossrefGoogle Scholar2. BARTELSPERKIN ECHJ: Liver function in hyperthyroidism as determined by hippuric acid test, New England Jr. Med., 1937, ccxvi, 1051-1060. CrossrefGoogle Scholar3. BOYCEMCFETRIDGE FFEM: Studies of hepatic function by quick hippuric acid test; thyroid disease, Arch. Surg., 1938, xxxvii, 427-442. CrossrefGoogle Scholar4. EUFINGERSPIEGLER HR: Der Einfluss des mensuellen Zyklus auf den Wasserstoffwechsel, Arch. f. Gynäk., 1928, cxxxv, 223-231. CrossrefGoogle Scholar5. HARPUDER K: Pharmakologische Beeinflussung des Purinstoffwechsels beim Menschen, Ztschr. f. d. ges. exper. Med., 1924, xlii, 1. CrossrefGoogle Scholar6. HEILIG R: Menstruationsstudien I, Klin. Wchnschr., 1924, iii, 576. CrossrefGoogle Scholar7. HEILIG R: Menstruationsstudien II. Wasser- und Kochsalzhaushalt, Klin. Wchnschr., 1924, iii, 1117-1119. CrossrefGoogle Scholar8. HIRSHEIMER A: Synthesis and excretion of hippuric acid in pregnancy, Am. Jr. Obst. and Gynec., 1935, xxix, 395-405. CrossrefGoogle Scholar9. KÜSTNER H: Bedeutung der Funktionen der weiblichen Genitalorgane für den renalen Diabetes, Arch. f. Gynäk., 1922, cxvii, 158. CrossrefGoogle Scholar10. MAUTHNERPICK HEP: Über die durch Schockgifte erzeugten Zirkulationsstörungen. II. Das Verhalten der überlebenden Leber, Biochem. Ztschr., 1922, cxxvii, 72-93. Google Scholar11. MOLITORPICK HEP: Zur Kenntnis der Diuresehemmung durch Hypophyssenpräparate, Klin. Wchnschr., 1923, ii, 2242. CrossrefGoogle Scholar12. QUICK AJ: Conjugation of benzoic acid in man, Jr. Biol. Chem., 1931, xcii, 65-85. CrossrefGoogle Scholar13. QUICK AJ: Effect of exercise on the excretion of uric acid, with note on influence of benzoic acid on uric acid elimination in liver diseases, Jr. Biol. Chem., 1935, cx, 107-112. CrossrefGoogle Scholar14. SIEBURGPATZSCHKE EW: Menstruation und Cholinstoffwechsel, Ztschr. f. d. ges. exper. Med., 1923, xxxvi, 324. CrossrefGoogle Scholar15. SNAPPERGRÜNBAUM IA: The non-excretory functions of the kidney, Proc. Staff Meet. Mayo Clin., 1927, ii, 300. Google Scholar16. SNELL AM: New tests of hepatic function, Collected papers of the Mayo Clinic, 1935, xxvii, 106-108. Google Scholar17. SHERWOOD TC: Further studies on ovarian-thyroid relationship, Endocrinology, 1940, xxvii, 925-928. CrossrefGoogle Scholar18. SRIKANTIASHAMANNARAGHUNATHA CD: Studies in blood sugar I., Proc. Ind. Acad. Sci., 1938, vii, B. 225. CrossrefGoogle Scholar19. THORNNELSONTHORN GWKRDW: Study of the mechanism of edema associated with menstruation, Endocrinology, 1938, xxii, 155-163. CrossrefGoogle Scholar20. THORNEMERSON GWK: Rôle of gonadal and adrenal cortical hormones in production of edema, ANN. INT. MED., 1940, xiv, 757-769. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Medical College University of Mysore Mysore, South India*Received for publication June 2, 1941. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe hippuric acid index: Application of the hippuric acid test as an index of human free anxietyDie Krankheiten der Leber und der GallenwegeÜber den Hippursäuretest nach QuickNutritional Therapy of Endocrine Disturbances 1 March 1942Volume 16, Issue 3Page: 538-546KeywordsExcretionGlycineLiverPregnancyResearch laboratoriesSodium ePublished: 1 December 2008 Issue Published: 1 March 1942 PDF downloadLoading ...