SUBARACHNOID HEMORRHAGE FOLLOWING INJECTION OF EPINEPHRINE
Authors: Morris Flexner, Bernard Schneider
Journal: Annals of Internal Medicine (1938)

Case Reports1 December 1938SUBARACHNOID HEMORRHAGE FOLLOWING INJECTION OF EPINEPHRINEMORRIS FLEXNER, M.D., F.A.C.P., BERNARD SCHNEIDER, M.D., D.N.B.MORRIS FLEXNER, M.D., F.A.C.P.Search for more papers by this author, BERNARD SCHNEIDER, M.D., D.N.B.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-12-6-876 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptEpinephrine is regarded as a harmless drug, the only common contraindications being angina pectoris and hypertension. Its use in the field of allergy is practically universal. Serious complications following its subcutaneous administration are not reported. Hence, we feel that the occurrence of a subarachnoid hemorrhage following the subcutaneous injection of 0.5 c.c. of epinephrine 1/1000 solution is of sufficient interest to be reported in detail.SUBARACHNOID HEMORRHAGEThe recognition of subarachnoid hemorrhage as a clinical entity has been greatly simplified since the report of Symonds and Cushing1in 1923, dealing with intracranial aneurysm. Previous to this, the reports were largely...Bibliography1. SYMONDSCUSHING CPH: Contributions to the clinical study of intracranial aneurysms, Guy's Hosp. Rep., April, 1923. Google Scholar2. SYMONDS CP a. : Spontaneous subarachnoid hemorrhage, Quart. Jr. Med., 1924, xviii, 93. b. GOLDFLAM, S.: Beiträge zur Ätiologie und Symptomatologie der spontanen subarachnoidalen Blutungen, Deutsch. Ztschr. f. Nervenh., 1923, lxxvi, 158. c. MCIVER, J., and WILSON, G.: Spontaneous subarachnoid hemorrhage, Jr. Am. Med. Assoc., 1923, xciii, 89. d. BARKER, L. F.: Spontaneous subarachnoid hemorrhage, ANN. INT. MED., 1936, x, 98. e. See references 1, 3a, 3b, 3d. f. SAVITSKY, N.: Diseases of the meninges, Nelson Loose Leaf Medicine, Volume VI, Chap. XXV, p. 5491. g. TAYLOR, A. B., and WHITFIELD, A. G. W.: Subarachnoid hemorrhage, Quart. Jr. Med., 1936, v, 641. h. SCHMIDT, M.: Intracranial aneurysms, Brain, 1930, liii, 489. i. STRAUSS, I., GLOBUS, J. H., and GINSBURG, S. W.: Spontaneous subarachnoid hemorrhage, Arch. Neur. and Psych., 1932, xxvii, 1080. CrossrefGoogle Scholar3. SCHWENKENBURG AJ a. : Spontaneous subarachnoid hemorrhage, Texas St. Med. Jr., 1933, xxviii, 814. b. RUSSELL, C. K.: Spontaneous subarachnoid hemorrhage, Canad. Med. Assoc. Jr., 1933, xxviii, 133. c. STROINK: Subarachnoid hemorrhages in connection with pregnancy, Nederl. tijdschr. v. verlosk. en gynaec., 1936, xxxix, 240. d. SMITH, W. A.: Spontaneous subarachnoid hemorrhage, South. Med. Jr., 1930, xxiii, 494. Google Scholar4. EPPINGER : as quoted by Fearnsides.6 Google Scholar5. 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Johns Hopkins Hosp., 1930, xlvii, 22. Google Scholar23. Personal communication to the authors. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Louisville, Kentucky*Received for publication January 6, 1938. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySystemic Reactions*Cerebral complications incurred during pregnancy and the puerperiumFATAL CASE OF SUBARACHNOID HEMORRHAGE UNDER INSULIN-CARDIAZOL TREATMENT OF A PSYCHOTIC PATIENTCerebrovascular accidents following epinephrine injections 1 December 1938Volume 12, Issue 6Page: 876-882KeywordsAllergy and immunologyAneurysmsAnginaDrugsEpinephrineHypertensionSubarachnoid hemorrhageSubcutaneous injections ePublished: 1 December 2008 Issue Published: 1 December 1938 PDF downloadLoading ...