THE EFFECT OF STREPTOMYCIN ON TUBERCULOUS MENINGITIS
Authors: H D BRAINERD, H R EAGLE
Journal: Annals of Internal Medicine (1950)

Article1 August 1950THE EFFECT OF STREPTOMYCIN ON TUBERCULOUS MENINGITISHENRY D. BRAINERD, M.D., HENRY R. EAGLE, M.D.HENRY D. BRAINERD, M.D., HENRY R. EAGLE, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-33-2-397 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSince the initial report by Cooke, Dunphy and Blake1 of an infant treated successfully with streptomycin for tuberculous meningitis, numerous individual case reports have appeared. The fact that many of these reports have described arrest of the disease without prolonged follow-up has created an impression of optimism.More extensive series have tempered this initial enthusiasm. Hinshaw, Feldman and Pfuetzer2reported nine cases of tuberculous meningitis, of whom two had completed six months of treatment and had continued to improve two and three months after the cessation of therapy. In a report to the Council on Pharmacy and Chemistry3of 91...Bibliography1. CookeDunphyBlake REDLFG: Streptomycin in tuberculous meningitis. A report of its use in a one-year old infant, Yale J. Biol. and Med. 18: 221, 1946. MedlineGoogle Scholar2. HinshawFeldmanPfuetzer HCWHKH: Treatment of tuberculosis with streptomycin. A summary of observations on one hundred cases, J. A. M. A. 132: 778, 1946. CrossrefMedlineGoogle Scholar3. Report to the Council on Pharmacy and Chemistry of the AMA by the Veterans Administ. Army and Navy: The effects of streptomycin on tuberculosis in man, J. A. M. A. 135: 634, 1947. MedlineGoogle Scholar4. McDermottMuschenheimHadleyBunnGorman WCSJPARV: Streptomycin in the treatment of tuberculosis in humans. I. Meningitis and generalized hematogenous tuberculosis, Ann. Int. Med. 27: 769, 1947. LinkGoogle Scholar5. Keith HM: Use of chemotherapy in a case of tuberculous meningitis, Proc. Staff Meet., Mayo Clin. 19: 36, 1944. Google Scholar6. Lincoln EM: Tuberculous meningitis in children. I. Tuberculous meningitis, Am. Rev. Tuberc. 56: 75, 1947. MedlineGoogle Scholar7. Current Comment—Dosage of streptomycin in tuberculosis, J. A. M. A. 135: 842, 1947. Google Scholar8. AmbersonStearns JBWH: Streptomycin in the treatment of tuberculosis, Ann. Int. Med. 29: 221, 1948. LinkGoogle Scholar9. Rigdon RH: Transverse myelitis accompanying tuberculous meningitis, Am. Rev. Tuberc. 55: 332, 1947. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication August 16, 1949.From the Infectious Disease Laboratory of the San Francisco Hospital, San Francisco, and the Division of Pediatrics of the Stanford Medical School, San Francisco, California. This laboratory is supported by the Divisions of Medicine and Pediatrics of the University of California Medical School, and by the Department of Public Health of the City and County of San Francisco.Presented before the Annual Meeting of the Western Section of the American Federation for Clinical Research in Los Angeles, October 14, 1948. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byTHE PRESENT STATUS OF THE TREATMENT OF TUBERCULOSIS OF THE CENTRAL NERVOUS SYSTEMThe Treatment of Tuberculous MeningitisMode of action of streptomycin in relation to thechanges in spinal fluid sugar in tuberculous meningitisMode of action of streptomycin in relation to thechanges in spinal fluid sugar in tuberculous meningitisTreatment of tuberculous meningitis in childrenTuberculous meningitis 1 August 1950Volume 33, Issue 2Page: 397-410KeywordsChild healthEpileptic seizuresInfantsInfectious diseasesMeningitisPediatricsPrevention, policy, and public healthResearch laboratoriesStreptomycin Issue Published: 1 August 1950 PDF downloadLoading ...