MULTIPLE HEMATOLOGIC ABNORMALITIES IN A CASE OF POSTNECROTIC CIRRHOSIS
Authors: S P MILLER, E SHANBROM
Journal: Annals of Internal Medicine (1961)

Case Reports1 March 1961MULTIPLE HEMATOLOGIC ABNORMALITIES IN A CASE OF POSTNECROTIC CIRRHOSISSHERWOOD P. MILLER, M.D., EDWARD SHANBROM, M.D.SHERWOOD P. MILLER, M.D.Search for more papers by this author, EDWARD SHANBROM, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-54-3-521 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptA great variety of hematologic disturbances may be associated with hepatocellular disease. There is no close correlation between the histopathology of the liver disease and the variety or degree of hematologic disorder. Several clinicopathologic reviews of postnecrotic cirrhosis of the liver have appeared,1-4 but generally few details regarding the hematologic picture in this disorder are given. It is the purpose of this paper to report a case of postnecrotic cirrhosis which manifested hemolytic anemia, fibrinolysis, lymphocytosis, and abnormalities in hemoglobin synthesis.CASE REPORTA 45-year-old white male was admitted to the City of Hope Medical Center in March, 1957, complaining...Bibliography1. RatnoffPatek ODAJ: Post-necrotic cirrhosis of the liver. J. Chron. Dis. 1: 266, 1955. CrossrefMedlineGoogle Scholar2. McDonaldMallory RAGK: The natural history of post-necrotic cirrhosis. Amer. J. Med. 24: 334, 1958. CrossrefMedlineGoogle Scholar3. BaggenstossStauffer AHMH: Post-hepatic and alcoholic cirrhosis: clinicopathological study of 43 cases of each. Gastroenterology 22: 157, 1952. CrossrefMedlineGoogle Scholar4. Sherlock S: Post-hepatitis cirrhosis. Lancet 1: 817, 1948. CrossrefMedlineGoogle Scholar5. Miller SP: Congenital deficiency of proconvertin: a clinical and laboratory report. Blood 14: 1322-1338 (Dec.) 1959. CrossrefMedlineGoogle Scholar6. 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Clin. Invest. 34: 390, 1955. CrossrefMedlineGoogle Scholar29. ChaplinMollison HPL: Red cell life-span in nephritis and hepatic cirrhosis. Clin. Sc. 12: 351, 1953. MedlineGoogle Scholar30. WassermanStatsSchwartzFudenberg LRDLH: Symptomatic and hemopathic hemolytic anemia. Amer. J. Med. 18: 961, 1955. CrossrefMedlineGoogle Scholar31. HavensMarch WPRE: The leukocyte response of patients with experimentally induced infectious hepatitis. Amer. J. Med. Sci. 212: 129, 1946. CrossrefMedlineGoogle Scholar32. Wintrobe MM: Clinical hematology, 4th Ed. Lea & Febiger, Philadelphia, p. 244, 1956. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Orange, California*Received for publication November 24, 1959.From the Hematology Service, City of Hope Medical Center, Duarte, California.†Present address: Maimonides Hospital of Brooklyn, Brooklyn, N. Y.‡Present address: Orange County Hospital, Orange, California.Requests for reprints should be addressed to Sherwood P. Miller, M.D., Division of Neoplastic Disease, Maimonides Hospital of Brooklyn, 4802 Tenth Avenue Brooklyn 19, N. Y. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byProgressive hypersplenism after portacaval anastomosisHemolytic Anemia Associated with Liver Disease 1 March 1961Volume 54, Issue 3Page: 521-535KeywordsBlood plasmaCirrhosisFibrinolysisHematology and oncologyHemolytic anemiaLiverLiver diseasesPerceptionSepsisSteroid therapy ePublished: 1 December 2008 Issue Published: 1 March 1961 PDF downloadLoading ...