ALLERGY TO INJECTABLE LIVER EXTRACTS; CLINICAL AND IMMUNOLOGICAL OBSERVATIONS
Authors: Samuel M. Feinberg, Howard L. Alt, Richard H. Young
Journal: Annals of Internal Medicine (1943)

Article1 March 1943ALLERGY TO INJECTABLE LIVER EXTRACTS; CLINICAL AND IMMUNOLOGICAL OBSERVATIONSSAMUEL M. FEINBERG, M.D., F.A.C.P., HOWARD L. ALT, M.D., RICHARD H. YOUNG, M.D., F.A.C.P.SAMUEL M. FEINBERG, M.D., F.A.C.P., HOWARD L. ALT, M.D., RICHARD H. YOUNG, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-18-3-311 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe last two or three decades have witnessed tremendous and far-reaching advances in therapeutics, in many instances specific in character. This has been particularly true in the case of highly potent injectable substances such as immune sera, hormones, vitamins, and such specific factors as the antianemic liver fraction. With the older types of materials allergic reactions such as asthma, urticaria or serum sickness were obtained and were not unexpected, since they contained a considerable quantity of the animal proteins which were regarded as an essential feature of the mechanism of the reaction. Later, it was shown that even such a...References1. HARTENWALZER MM: Allergy to insulin, liver, pituitary, pancreas, estrogens, enzymes, and similar substances, Jr. Allergy, 1940, xii, 72. CrossrefGoogle Scholar2. GRUEN G: Hypersensitiveness to parenterally administered liver preparation in a case of pernicious anemia, Wien. klin. Wchnschr., 1934, xlvii, 751. Google Scholar3. DIENA D: Hypersensitivity to liver preparation, Gior. d. r. Accad. di med. di Torino, 1938, ci, 462. Google Scholar4. LASCH F: Concerning allergic symptoms due to parenteral liver therapy, Wien. med. Wchnschr., 1936, lxxxvi, 126. Google Scholar5. CRIEP LH: Allergy to liver extract, Jr. Am. Med. Assoc., 1937, cx, 506. Google Scholar6. PASCHE HD: Observations on a case of allergy to liver extract, Deutsch. med. Wchnschr., 1939, lxv, 1192. Google Scholar7. JONES CA: Allergic reactions following the parenteral administration of liver extract, New Internat. Clin., 1939, iii, 259. Google Scholar8. GRAYBOWMAN IKL: In press. Google Scholar9. ENGEL L: Anaphylaxis to a liver preparation in a case of pernicious anemia, Bol. Assoc. med. de Puerto Rico, 1933, xxv, 326. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Chicago, Illinois*Received for publication February 5, 1942.From the Division of Allergy and the Hematology Clinic, Department of Medicine, Northwestern University Medical School. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDietary Use of Liver Through the AgesAllergic Reactions in Parenteral Liver Therapy and Vitamin B12Use of antihistaminic drugs in treating patients allergic to liver extractFifth Announcement of the U.S.P. Anti-Anemia Preparations Advisory BoardSensitivity to Pork-Liver Extract in Pernicious AnemiaArthus type of sensitivity to liver extract 1 March 1943Volume 18, Issue 3Page: 311-322KeywordsAllergy and immunologyAsthmaClinical immunologyHematology and oncologyHormonesLiverSerum proteinsUrticariaVitamins Issue Published: 1 March 1943 PDF downloadLoading ...