MYXEDEMA HEART: A PATHOLOGICAL AND THERAPEUTIC STUDY
Authors: John S. La Due
Journal: Annals of Internal Medicine (1943)

Article1 March 1943MYXEDEMA HEART: A PATHOLOGICAL AND THERAPEUTIC STUDYJOHN S. LA DUE, M.D.JOHN S. LA DUE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-18-3-332 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThis report presents the autopsy findings in a patient dying of heart failure due to myxedema and points out the similarity of her myocardial lesions to those found in the beriberi heart. The case history of another patient with myxedema heart treated with thiamin and vitamin B complex and then with thyroid extract is reviewed.The clinical syndrome of heart failure sometimes associated with hypothyroidism (myxedema heart) was first described by Zondek1in 1918. It was later recognized in this country by Fahr2and has since been discussed by many investigators.3Hallock4showed that the cardiac output of the myxedema...Bibliography1. ZONDEK H: Das Myxödemherz, München. med. Wchnschr., 1918, lxv, 1180. Google Scholar2. FAHR G: Myxedema heart, Jr. Am. Med. Assoc., 1925, lxxxiv, 345. CrossrefGoogle Scholar3. ASSMANN H: Das Myxödemherz, München. med. Wchnschr., 1919, lxvi, 9. WILLINS, F., and HAINES, S.: Status of the heart in myxedema, Am. Heart Jr., 1925, i, 67. HOLZMAN, J.: Myxedema heart, Am. Heart Jr., 1929, iv, 351. Google Scholar4. HALLOCK P: The heart in myxedema, with a report of two cases, Am. Heart Jr., 1933, ix, 196. CrossrefGoogle Scholar5. SCHULTZ A: Ueber einen Fall von Athyrosis congenita (Myxödem), Virchow's Arch. f. path. Anat., 1921, ccxxxii, 302. CrossrefGoogle Scholar6. BEHRMÜLDER EJ: Het Myxoedeemhart, Een Pathologisch-Anatomische Bijdrage, Nederl. Tijdschr. v. Geneesk., 1938, lxxxii, 4303. Google Scholar7. 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LÖHR H: Diätetische und Vitamintherapie des Morbus Basedow, Med. Welt, 1937, xi, 111. Google Scholar20. MEANSHERTZLERMAN JSJ: Nutritional factors in Graves' disease, ANN. INT. MED., 1937, xi, 429. Google Scholar21. FRAZIERRAVDIN WI: The use of vitamin B1 therapy in the preoperative preparation of the hyperthyroid patient, Surgery, 1938, iv, 680. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: JOHN S. LA DUE, M.D.Affiliations: New Orleans, Louisiana*Received for publication April 22, 1941.From the Department of Medicine at the Minneapolis General Hospital and the University of Minnesota Medical School, Minneapolis, Minnesota. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThyroid and the Heart: A Historical PerspectiveChest Pain in the Setting of Altered Mental StatusA rabbit model of fatal hypothyroidism mimicking &ldquo;myxedema coma&rdquo; established by microscopic total thyroidectomyTHE HYPOTHYROID STATESLeft ventricular function at rest and during exercise in acute hypothyroidism.Influence of L-thyroxine on cardiac function in athyreotic thyroid cancer patients — An echophonocardiographic studyCardiac dimensions and myocardial function of infants with congenital hypothyroidism. An echocardiographic study.PERICARDIAL EFFUSION IN HYPOTHYROIDISMCompromise therapy in the patient with angina pectoris and hypothyroidismEchocardiographic characterization of the reversible cardiomyopathy of hypothyroidismNoninvasive Evaluation of Cardiac Function in HypothyroidismCARDIAL COLLOIDMyxedema and Coronary Artery Disease—A Comparative Autopsy StudyALFRED D. 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ROOF, M.D.Mean spatial vectorcardiographyNEPHROSIS AND HYPOTHYREOSIS1,2Hypothyroidism and mild myxedema from thiocyanate intoxicationManagement of the myxedematous patient with symptoms of cardiovascular disease 1 March 1943Volume 18, Issue 3 Page: 332-344 Keywords Beriberi Cardiac output Heart Heart failure Hospital medicine Hypothyroidism Lesions Longitudinal studies Thiamine Thyroid ePublished: 1 December 2008 Issue Published: 1 March 1943 PDF downloadLoading ...