GIANT FOLLICLE HYPERPLASIA: A STUDY OF ITS INCIDENCE, HISTOPATHOLOGIC VARIABILITY, AND THE FREQUENCY OF SARCOMA AND SECONDARY HYPERSPLENIC COMPLICATIONS
Authors: T S EVANS, C A DOAN
Journal: Annals of Internal Medicine (1954)

Article1 May 1954GIANT FOLLICLE HYPERPLASIA: A STUDY OF ITS INCIDENCE, HISTOPATHOLOGIC VARIABILITY, AND THE FREQUENCY OF SARCOMA AND SECONDARY HYPERSPLENIC COMPLICATIONSTHEODORE S. EVANS, M.D., F.A.C.P., CHARLES A. DOAN, M.D., F.A.C.P.THEODORE S. EVANS, M.D., F.A.C.P.Search for more papers by this author, CHARLES A. DOAN, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-40-5-851 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAn increasing number of patients with known chronic constitutional disease are being recognized in whom, during a period of satisfactory therapeutic control, either basic qualitative cellular alterations occur, or complicating secondary cytopenic episodes16develop, which are more immediately incapacitating and life-threatening than the primary dyscrasia itself. Under these circumstances, it is essential to reëvaluate promptly the fundamental underlying pathologic-physiology. It has been found to be most important to differentiate monocytopenia and pancytopenia particularly carefully, as due either to central bone marrow invasion or damage, or to someperipheralmechanism—with special reference to one of the so-called secondary hypersplenic or dysplenic...Bibliography1. BaehrKlempererRosenthal GPN: Follicular lymphoblastoma (giant follicular hyperplasia of lymph nodes and spleen), Am. J. Path. 7: 558, 1931. Google Scholar2. BaehrRosenthal GN: Malignant lymph follicle hyperplasia of spleen and lymph nodes, Am. J. Path. 3: 550, 1927. Google Scholar3. Baehr G: The clinical and pathological picture of follicular lymphoblastoma, Tr. A. Am. Physicians 47: 330, 1932. Google Scholar4. BaggenstossHeck AHFJ: Follicular lymphoblastoma (giant lymph follicle hyperplasia of the lymph nodes and spleen), Am. J. M. Sc. 200: 17, 1940. CrossrefGoogle Scholar5. 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Author, Article, and Disclosure InformationAffiliations: *Received for publication January 2, 1954.From The Lymphoma Clinic, the Division of Research Hematology, Department of Medicine, Ohio State University, Columbus, Ohio, and The Yale University School of Medicine, and the Grace Unit of the Grace New Haven Hospital, New Haven, Connecticut.Presented in part before the International Hematology Congress, Cambridge, England, August, 1950. Nextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byHistorical perspectiveHistological Classification of Lymphomas (NISBET SYMPOSIUM, OCTOBER 1972)Ataxia telangiectasia with granulocytopeniaTolerance of chemotherapy following splenectomy for leukopenia or thrombocytopenia in patients with malignant lymphomasGiant follicular lymph node diseaseDie Brill-Symmers-Erkrankung in laryngologischer SichtGiant follicle lymphomaGiant follicular lymphoblastomaGIANT FOLLICULAR LYMPHOBLASTOMA: ITS TREATMENT WITH RADIOISOTOPES*†JOHN H. LAWRENCE, M.D., D.SC., F.A.C.P., WILLIAM G. DONALD JR., M.D.Follicular lymphoma.A re-evaluation of its position in the scheme of malignant lymphoma based on a survey of 253 casesUnusual Morphologic Changes in the Liver in a Case of Acute Hepatic Failure 1 May 1954Volume 40, Issue 5Page: 851-880KeywordsBone marrowHematology and oncologyHospital medicineLymphomaSarcoma ePublished: 1 December 2008 Issue Published: 1 May 1954 Copyright & PermissionsCopyright, 1954, by The American College of PhysiciansPDF downloadLoading ...