WALDENSTRÖM'S MACROGLOBULINEMIA WITH CRYOGLOBULINEMIA
Authors: M S SIRRIDGE
Journal: Annals of Internal Medicine (1960)

Case Reports1 August 1960WALDENSTRÖM'S MACROGLOBULINEMIA WITH CRYOGLOBULINEMIAMARJORIE S. SIRRIDGE, M.D.MARJORIE S. SIRRIDGE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-53-2-380 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptPrimary macroglobulinemia is a rare disease which was first described in 1944 by Waldenström.1Using the ultracentrifuge, he identified abnormal proteins with high sedimentation constants in two patients who had many findings similar to those seen in multiple myeloma. The distinctive features of these cases were anemia, epistaxis, slight lymphadenopathy, lymphocytoid cells in the bone marrow, generalized osteoporosis, and the presence of macroglobulins in the serum. In one of these patients the abnormal globulin also was found to be a cryoglobulin. 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PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byLymphocyte and plasma cell neoplasms associated with autoimmune diseasesThe association of rheumatoid arthritis with plasma cell and lymphocytic neoplasmsPrimary macroglobulinemiaWaldenstrom type macroglobulinaemia in a Nigerian with rheumatoid arthritisMacroglobulinaemia: Primary (Waldenstrom) and Symptomatic in Rheumatoid Arthritis 1 August 1960Volume 53, Issue 2Page: 380-388KeywordsAnemiaBone marrowCellsGlobulinsHematology and oncologyHypergammaglobulinemiaMultiple myelomaOsteoporosisProteinsUltracentrifugation ePublished: 1 December 2008 Issue Published: 1 August 1960 PDF downloadLoading ...