ADDICTION TO BARBITURATES AND THE BARBITURATE ABSTINENCE SYNDROME
Authors: H ISBELL
Journal: Annals of Internal Medicine (1950)

Article1 July 1950ADDICTION TO BARBITURATES AND THE BARBITURATE ABSTINENCE SYNDROMEHARRIS ISBELL, M.D., F.A.C.P.HARRIS ISBELL, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-33-1-108 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe purpose of this paper is to point out that chronic intoxication with barbiturates represents a true addiction—no matter how addiction is defined—and to describe the manifestations of maintained intoxication with barbiturates as well as the signs and symptoms which occur following withdrawal of these drugs from chronically intoxicated individuals.The increasing incidence of acute intoxication with barbiturates is unquestioned. Production of the barbiturates in the United States has increased 400 per cent since 1933. In 1948, over 300 tons of these drugs were manufactured.1Acute intoxication with barbiturates accounts for about 25 per cent of all cases of acute...Bibliography1. : Synthetic organic chemical production and sales, 1948, U. S. Government Printing Office, Washington, D. C. Google Scholar2. RubitskyMyerson HSHM: Acute phosphorous poisoning, Arch. Int. Med. 83: 164, 1949. CrossrefGoogle Scholar3. : Accident fatalities in the United States, 1946. Vital Statistics Special Reports, National Summaries 29: 238, 1949. Google Scholar4. : Barbiturates leading cause of fatal accidental poisoning, Statist. Bull. Metropolitan Life Insur. Co. 29: 7, 1948. MedlineGoogle Scholar5. Goldstein SW: Barbiturates: a blessing and a menace, J. Am. Pharm. A. (Scient. Ed.) 36: 5, 1947. CrossrefGoogle Scholar6. Trichter JC: Control over the barbiturates and their public health importance, J. Quart. Bull. Assoc. Food and Drug Officials 9: 127, 1946. Google Scholar7. 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Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: HARRIS ISBELL, M.D., F.A.C.P.Affiliations: Lexington, Kentucky*Presented before the 31st Annual Session of the American College of Physicians, Boston, April 20, 1950.From the National Institute of Mental Health of the National Institutes of Health, Public Health Service. (Clinical studies at the U. S. Public Health Service Hospital, Lexington, Kentucky.) 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F. FRASER, M.D., M. R. SHAVER, M.D., E. S. MAXWELL, M.D., H. ISBELL, M.D., F.A.C.P.Treatment of drug addiction 1 July 1950Volume 33, Issue 1Page: 108-121KeywordsDrug addictionDrugsIntoxicationMedical servicesPrevention, policy, and public healthPsychiatry and mental healthSigns and symptoms ePublished: 1 December 2008 Issue Published: 1 July 1950 PDF downloadLoading ...