AN ATYPICAL HEMOLYSIN IN PREGNANCY
Authors: Philip Levine, Silik H. Polayes
Journal: Annals of Internal Medicine (1941)

Case Reports1 April 1941AN ATYPICAL HEMOLYSIN IN PREGNANCYPHILIP LEVINE, M.D., SILIK H. POLAYES, M.D.PHILIP LEVINE, M.D.Search for more papers by this author, SILIK H. POLAYES, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-14-10-1903 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe case to be reported is one of 12 (of which five were selected from the literature) recently cited in support of the hypothesis that the pregnant woman under certain conditions may be immunized by the products of conception; i.e., fetus or placenta.1This hypothesis was offered by Levine and Stetson2as an explanation for the origin of an atypical agglutinin with the properties of an immune antibody, observed in a pregnant woman never previously transfused. It was assumed that the patient, who had harbored a dead fetus for two months, was immunized by an agglutinogen in the blood or...Bibliography1. LEVINEKATZIN PEM: Isoimmunization in pregnancy and the varieties of isoagglutinins observed, Proc. Soc. Exper. Biol. and Med., 1940, xlv, 343-346. CrossrefGoogle Scholar2. LEVINESTETSON PRE: An unusual case of intra-group agglutination, Jr. Am. Med. Assoc., 1939, cxiii, 126-127. CrossrefGoogle Scholar3. PARRKRISCHNER LWH: Hemolytic transfusion fatality with donor and recipient in the same blood group, Jr. Am. Med. Assoc., 1932, xcviii, 47. CrossrefGoogle Scholar4. NETER E: Observations on abnormal isoantibodies following transfusions, Jr. Immunol., 1936, xxx, 255-259. Google Scholar5. DEGOWIN EL: Grave sequelae of blood transfusions: a clinical study of 13 cases occurring in 3500 blood transfusions, ANN. INT. MED., 1938, xi, 1777-1791. Google Scholar6. MANDELBAUM H: Hemolytic reaction following blood transfusion: report of a case of intra-group incompatibility, ANN. INT. MED., 1939, xii, 1699-1708. Google Scholar7. BRAINARD HH: Renal insufficiency following transfusion of compatible blood, Am. Jr. Obst. and Gynec., 1940, xl, 142-144. CrossrefGoogle Scholar8. JONSSON B: Zur Frage der heterospezifischen Schwangenschaft, Acta Path. e. Micr. Scand., 1936, xiii, 424-433. Google Scholar9. LEVINELANDSTEINER PK: On immune isoagglutinins in rabbits, Jr. Immunol., 1929, xvii, 559-565. Google Scholar10. LANDSTEINERWIENER KAS: An agglutinable factor in human blood recognized by immune sera for Rhesus blood, Proc. Soc. Exper. Biol. and Med., 1940, xliii, 223. CrossrefGoogle Scholar11. WIENERPETERS ASHR: Hemolytic reactions following the transfusion of blood of the homologous group with three cases in which the same agglutinogen was responsible, ANN. INT. MED., 1940, xiii, 2306-2322. Google Scholar12. LANDSTEINERLEVINE KP: On isoagglutinin reactions of human blood other than those defining the blood groups, Jr. Immunol., 1929, xvii, 1-28. Google Scholar13. OEHLECKER F: Erfahrungen aus 170 direkten Bluttransfusionen von Vene zu Vene, Arch. f. klin. Chir., 1921, cvi, 705-719. Google Scholar14. LANDSTEINERVAN DER SCHEER KJ: On the antigens of red blood corpuscles, Jr. Exper. Med., 1925, xli, 427-437. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication September 13, 1940.From the Division of Laboratories, Newark Beth Israel Hospital, Newark, New Jersey, and the Department of Pathology of the Cumberland Hospital, Brooklyn, New York.Aided by a grant from the Blood Transfusion Betterment Association of New York City. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byABO, H, LE, P1PK, GLOB, I and FORS Blood Group SystemsCommentary on and reprint of Levine P, Burnham L, Katzin EM, Vogel P, The role of isoimmunization in the pathogenesis of erythroblastosis fetalis, in American Journal of Obstetrics and Gynecology (1941) 42:925–937Anämien des KindesABO-Inkompatibilit�t als m�gliche Sterilit�tsursacheMorbus haemolyticus neonatorum infolge AB0-Inkompatibilität und seltene foetogene SensibilisierungenABO Incompatibility in the Etiology of Hemolytic Disease of the Newborn**Presented at the Twenty-fourth Annual Meeting of the Central Association of Obstetricians and Gynecologists, New Orleans, La., Oct. 4, 5, and 6, 1956.Neuzeitliche Sicherungen bei BluttransfusionenA BRIEF REVIEW OF THE NEWER BLOOD FACTORSEin neues erbliches Antigen als Ursache gehäufter FehlgeburtenPresent status of Rh blood types and nomenclatureThe clinical significance of Rh antibodies (Rh agglutinins and blocking antibodies) in the sera of Rh-negative mothers; A study of 179 casesGENETIC AND CONSTITUTIONAL CAUSES OF FETAL AND NEONATAL MORBIDITYThe Rh factor in obstetricsBibliographyThe pathogenesis of erythroblastosis fetalisTreatment of hyperemesis gravidarum with intramuscular injections of husband's bloodThe role of iso-immunization in the pathogenesis of erythroblastosis fetalisPathogenesis of Erythroblastosis Fetalis: Statistical EvidenceThe Role of ISO-Immunization in the Pathogenesis of Erythroblastosis Fetalis 1 April 1941Volume 14, Issue 10Page: 1903-1908KeywordsAgglutininsBloodBlood transfusionFetusesPregnancy Issue Published: 1 April 1941 PDF downloadLoading ...