THYMOMA: DIAGNOSIS AND TREATMENT
Authors: W WEINGARTEN, G GORDON
Journal: Annals of Internal Medicine (1955)

Article1 February 1955THYMOMA: DIAGNOSIS AND TREATMENTWILLIAM WEINGARTEN, M.D., GLENN GORDON, M.D.WILLIAM WEINGARTEN, M.D.Search for more papers by this author, GLENN GORDON, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-42-2-283 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe diagnosis of thymoma can present much difficulty because of the unusual location, slow growth and lack of classic signs and symptoms.The thymus usually undergoes gradual regression at adolescence but may persist beyond puberty and produce no symptoms. When the thymus does not regress it may compress mediastinal structures, undergo malignant change or give rise to myasthenia gravis.Weigert1in 1901 first reported a case of myasthenia gravis associated with a thymoma. Since then, many reports confirming Weigert's findings have appeared in the medical literature. Seybold et al.2have found that 75.6% of their patients with myasthenia gravis had...Bibliography1. Weigert C: Pathologisch-anatomischer Beitrag zur Erb'schen Krankheit (Myasthenia gravis), Neurol. Centralbl. 20: 597-601, 1901. Google Scholar2. SeyboldMcDonaldClagettGood DWJROTCA: Tumors of the thymus, J. Thoracic Surg. 20: 195-215 (Aug.) 1950. CrossrefGoogle Scholar3. Harris VD: Intrathoracic growths, St. Barth. Hosp. Rep. London 28: 73, 1892. Google Scholar4. Ambrosini G: De l'epitheliome du thymus, Thèse de Paris, 1894. Google Scholar5. Jones AC: Lymphosarcoma of the thymus, Tr. Am. Laryng., Rhin. and Otol. Soc. 34: 478, 1928. Google Scholar6. Janeway HH: The treatment of malignant tumors of the thymus gland by radium, Ann. Surg. 71: 460, 1920. CrossrefMedlineGoogle Scholar7. Good CA: Roentgenologic findings in myasthenia gravis, Medicine 22: 1-25, 1943. Google Scholar8. CastlemanNorris BEN: The pathology of the thymus in myasthenia gravis: a study of 35 cases, Medicine 28: 27-58 (Feb.) 1949. CrossrefMedlineGoogle Scholar9. Grandhomme F: Ueber Tumoren des vorderen Mediastinum und ihre Beziehungen zu der Thymusdrüse, Inaug. Diss., Heidelberg, 1900. Google Scholar10. Crosby EH: Malignant tumor of the thymus gland, Am. J. Cancer 16: 461, 1932. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication May 29, 1954.From the Departments of Medicine and Thoracic Surgery, U. S. Public Health Service Hospital, Staten Island, N. Y.Published with permission of the Surgeon General, U. S. Public Health Service Hospital, Washington, D. C. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byTumors of the ThymusThymolipoma in patients with myasthenia gravis: report of two cases and reviewThe management of malignant thymoma with radiation therapyGutartige Primärtumoren der Bronchien und LungenLipothymoma simulating cardiomegaly: Case reportSurgery and the thymusCongestive heart failure in postmenopausal muscular dystrophy: Myositis, myocarditis, thymoma 1 February 1955Volume 42, Issue 2Page: 283-295KeywordsAdolescentsHospital medicineMedical servicesMyasthenia gravisPubertySigns and symptomsSurgeonsThoracic surgeryThymomaThymus ePublished: 1 December 2008 Issue Published: 1 February 1955 PDF downloadLoading ...