CHRONIC OBSTRUCTIVE PULMONARY EMPHYSEMA: A DISEASE OF SMOKERS
Authors: W FRANKLIN, F C LOWELL, A L MICHELSON, I W SCHILLER
Journal: Annals of Internal Medicine (1956)

Article1 August 1956CHRONIC OBSTRUCTIVE PULMONARY EMPHYSEMA: A DISEASE OF SMOKERSFRANCIS C. LOWELL, M.D., F.A.C.P., WILLIAM FRANKLIN, M.D., ALAN L. MICHELSON, M.D., IRVING W. SCHILLER, M.D.FRANCIS C. LOWELL, M.D., F.A.C.P.Search for more papers by this author, WILLIAM FRANKLIN, M.D.Search for more papers by this author, ALAN L. MICHELSON, M.D.Search for more papers by this author, IRVING W. SCHILLER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-45-2-268 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptDuring the last two years a number of patients with chronic obstructive emphysema have been observed while under treatment with bronchodilator agents and the adrenal steroids, in the course of which our attention was drawn to an association between pulmonary emphysema, peptic ulcer, carcinoma of the lung and a high incidence of smoking. The association between emphysema and smoking was so striking that we postulated that smoking is the major factor in the pathogenesis of emphysema in this area.1 The present report is a detailed analysis of the data on which this opinion was based.It was only after we...Bibliography1. LowellFranklinMichelsonSchiller FCWALIW: A note on the association of emphysema, peptic ulcer and smoking, New England J. Med. 254: 123-124, (Jan. 19) 1956. CrossrefMedlineGoogle Scholar2. AbbottHopkinsVan FleetRobinson OAWAWEJS: A new approach to pulmonary emphysema, Thorax 8: 116, 1953. CrossrefMedlineGoogle Scholar3. PhillipsPhillipsPaullPecora RWAMAMDV: Chronic bronchitis—a neglected disease entity, Dis. of Chest 26: 520, 1954. CrossrefMedlineGoogle Scholar4. FranklinMichelsonLowellSchiller WALFCIW: The clinical value of a tracing of forced expiration (expirogram), I. Pulmonary disease, New England J. Med. 253: 799, 1955. CrossrefMedlineGoogle Scholar5. BaldwinCournandRichards EdADW: Pulmonary insufficiency; physiological classification, clinical methods of analysis, standard values in normal subjects, Medicine 27: 243-278, 1948. CrossrefMedlineGoogle Scholar6. HammondHorn ECD: The relationship between human smoking habits and death rates, J. A. M. A. 155: 1316, 1954. CrossrefMedlineGoogle Scholar7. Spain DM: Pathogenetic concepts of some aspects of pulmonary disease, Am. J. Surg. 89: 118, 1955. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Boston, Massachusetts*Received for publication March 9, 1956.From the Evans Memorial and the Massachusetts Memorial Hospitals, and the Department of Medicine, Boston University School of Medicine, Boston, Massachusetts.Requests for reprints should be addressed to Francis C. Lowell, M.D., Evans Memorial Hospital, 65 East Newton St., Boston, Mass. 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TAYLOR, Ph.D.A Study of Illness in a Group of Cleveland FamiliesA clinico-pathologic study of Cor pulmonale with heart failure∗Bronchodilators and Corticosteroids in the Treatment of Obstructive Pulmonary EmphysemaDiffuse Obstructive Pulmonary Emphysema, a Poorly Understood DisorderTHE IRRITATIVE EFFECT OF SMOKING ON THE RESPIRATORY MUCOUS MEMBRANESPAUL W. CLOUGHCODING FOR CASE-NOTESSMOKING AND BRONCHITIS 1 August 1956Volume 45, Issue 2Page: 268-274KeywordsChronic obstructive pulmonary diseaseDyspneaEmphysemaHospital medicineLung and intrathoracic tumorsPathogenesisPeptic ulcersPulmonary diseasesRespiratory system proceduresSteroids ePublished: 1 December 2008 Issue Published: 1 August 1956 PDF downloadLoading ...