PSEUDO-PSEUDOHYPOPARATHYROIDISM: REPORT OF THREE CASES IN ONE FAMILY
Authors: N UHR, H B BEZAHLER
Journal: Annals of Internal Medicine (1961)

Article1 March 1961PSEUDO-PSEUDOHYPOPARATHYROIDISM: REPORT OF THREE CASES IN ONE FAMILYNATHANIEL UHR, M.D., F.A.C.P., HARVEY B. BEZAHLER, M.D.NATHANIEL UHR, M.D., F.A.C.P.Search for more papers by this author, HARVEY B. BEZAHLER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-54-3-443 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn 1942 Albright, Burnett, Smith, and Parson1 originated the term pseudohypoparathyroidism (PH) to describe a group of patients with round face, short stature, short metacarpals and metatarsals, ectopic ossifications, elevated serum phosphorus and low serum calcium values. What differentiated these patients from persons with idiopathic hypoparathyroidism was their failure to respond with a phosphate diuresis to parenteral administration of parathyroid extract.Ten years later the designation pseudo-pseudohypoparathyroidism (PPH) was employed by Albright, Forbes, and Henneman2in describing a 29-year-old woman who had many of the clinical features of PH but in whom the values for serum phosphorus and calcium were...Bibliography1. AlbrightBurnettSmithParson FCHPHW: Pseudohypoparathyroidism. Endocrinology 30: 922, 1942. Google Scholar2. AlbrightForbesHenneman FAPPH: Pseudo-pseudohypoparathyroidism. Trans. Ass. Amer. Physicians 65: 337, 1952. MedlineGoogle Scholar3. HordingPuupponenKoski HEK: Short metacarpal or metatarsal bones: pseudo-pseudohypoparathyroidism. J. Clin. Endocr. 20: 466, 1960. CrossrefGoogle Scholar4. RayGardner EWLI: Pseudo-pseudohypoparathyroidism in a child: report of the youngest case. Pediatrics 23: 520, 1959. MedlineGoogle Scholar5. 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SeringeTomkiewicz PHS: Pseudo-pseudohypoparathyroidisme familial. Ann. d'endocrinol. Paris 17: 655, 1956. MedlineGoogle Scholar12. Van der Werff ten Bosch JJ: The syndrome of brachymetacarpal dwarfism ("pseudo-pseudohypoparathyroidism") with and without gonadal dysgenesis. Lancet 1: 69, 1959. CrossrefMedlineGoogle Scholar13. Fromm GA: Concerning the term "pseudo-pseudohypoparathyroidism." J. Clin. Endocr. 16: 293, 1956. CrossrefGoogle Scholar14. Snapper I: Personal communication. Google Scholar15. McNeelyRaiszLeMay WFLGM: Dyschondroplasia with soft tissue calcification and ossification and normal parathyroid function ("pseudo-pseudohypoparathyroidism"). Amer. J. Med. 21: 649, 1956. CrossrefMedlineGoogle Scholar16. WallachEnglertBrown SEH: The syndrome of pseudo-pseudohypoparathyroidism. Arch. Intern. Med. 98: 517, 1956. CrossrefGoogle Scholar17. WintersGrahamWilliamsMcFallsBurnett RWJBTFVWCH: A genetic study of familial hypophosphatemic and vitamin D-resistant rickets with a review of the literature. Medicine 37: 97, 1958. CrossrefMedlineGoogle Scholar18. DicksonMoritaCowsertGravesMeyer LGYEJJJS: Neurological, electroencephalographic and heredo-familial aspects of pseudohypoparathyroidism and pseudo-pseudohypoparathyroidism. J. Neurol., Neurosurg., Psychiat. 23: 33, 1960. CrossrefMedlineGoogle Scholar19. CusmanoBakerFinby JVDHN: Pseudohypoparathyroidism. Radiology 67: 845, 1956. CrossrefMedlineGoogle Scholar20. McKusick VA: Personal communication. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: NATHANIEL UHR, M.D., F.A.C.P.; HARVEY B. BEZAHLER, M.D.Affiliations: Topeka, Kansas*Received for publication August 22, 1960.From The C. F. Menninger Memorial Hospital, Topeka, Kansas.Requests for reprints should be addressed to Nathaniel Uhr, M.D., F.A.C.P., The Menninger Foundation, Topeka, Kansas. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byImprinting in Albright's hereditary osteodystrophy.Hormonale Osteopathien im ErwachsenenalterHormonale Osteopathien im ErwachsenenalterAlbright's hereditary osteodystrophy: A reviewAutosomal dominant inheritance in Albright's hereditary osteodystrophyMineralization of the central nervous system in pseudopseudohypoparathyroidism (PPH).Röntgendiagnostik der Muskeln, Sehnen und Bänder Pathologische Verdichtungen und Aufhellungen im WeichteilmantelAlbright's Hereditary Osteodystrophy Report of a Family with Studies of Bone RemodelingA. ROBERT ARNSTEIN, M.D., BOY FRAME, M.D., F.A.C.P., HAROLD M. FROST, M.D., MELVIN A. BLOCK, M.D.PseudohypoparathyroidismAlbright's Hereditary Poly-Osteochondrodystrophy — (Pseudo-pseudo-hypoparathyroidism with diabetes hypertension, arteritis and polyarthrosis)Rheumatism and Arthritis Review of American and English Literature of Recent Years (Sixteenth Rheumatism Review)CHARLEY J. SMYTH, M.D., F.A.C.P., ROGER L. BLACK, M.D., CHARLES CHRISTIAN, M.D., MACK L. CLAYTON, M.D., F.A.C.S., DONALD F. HILL, M.D., F.A.C.P., JOSEPH LEE HOLLANDER, M.D., F.A.C.P., WILLIAM M. MIKKELSEN, M.D., F.A.C.P., MAX M. MONTGOMERY, M.D., F.A.C.P., CARL M. PEARSON, M.D., F.A.C.P., HUGH A. SMYTHE, M.D., F.R.C.P. (C), L. EMMERSON WARD, M.D., F.A.C.P., HOWARD J. WEINBERGER, M.D., F.A.C.P.The ParathyroidsReferencesMedical genetics 1961Albright's Hereditary Osteodystrophy Comprising Pseudohypoparathyroidism and Pseudo-pseudohypoparathyroidism With a Report of Two Cases Representing the Complete Syndrome Occurring in Successive GenerationsJOEL B. MANN, M.D., SEYMOUR ALTERMAN, M.D., A. GORMAN HILLS, M.D. 1 March 1961Volume 54, Issue 3 Page: 443-451 Keywords Calcium Clinical genetics Hypoparathyroidism Parathyroid Phosphates Phosphorus Pseudohypoparathyroidism ePublished: 1 December 2008 Issue Published: 1 March 1961 PDF downloadLoading ...