ACUTE PEPTIC ULCERATION FOLLOWING CARDIAC SURGERY
Authors: D BERKOWITZ, B M WAGNER, J F URICCHIO
Journal: Annals of Internal Medicine (1957)

Article1 June 1957ACUTE PEPTIC ULCERATION FOLLOWING CARDIAC SURGERYDONALD BERKOWITZ, M.D., BERNARD M. WAGNER, M.D., JOSEPH F. URICCHIO, M.D.DONALD BERKOWITZ, M.D., BERNARD M. WAGNER, M.D., JOSEPH F. URICCHIO, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-46-6-1015 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptA variety of stressful stimuli when applied to a susceptible host have been recorded as provoking an ulcerative response in the gastrointestinal tract. Thus burns,1-4 trauma,5-9 central nervous system disease10-20 and fractures21 have been implicated in the past.Surgery in particular has been well documented as an ulcerogenic stimulus.5, 6, 9, 22-30Recently, surgical technics have been developed for the therapy of many congenital and acquired heart lesions. As a general experience, these measures are exceptionally complicated and have been applied to patients chronically and severely ill. Thus the combination of a severely traumatic experience applied to a host with...Bibliography1. Curling TB: On acute ulceration of the duodenum in cases of burns, Med. Chir. Tr. London 25: 260, 1842. CrossrefMedlineGoogle Scholar2. Harkins HN: Acute ulcer of the duodenum (Curling's ulcer) as a complication of burns; relation to sepsis, Surgery 3: 608-641, 1938. Google Scholar3. Long J: Lond. Med. Gaz. 25: 743, 1840. Google Scholar4. WeigelArtzReissDavisAnspacher AECPEJHWA: Gastrointestinal ulcerations complicating burns: a report of five cases and a review of seventeen cases reported from 1942 to 1952, Surgery 34: 826-836, 1953. MedlineGoogle Scholar5. Roberts PA: A danger of peptic ulceration, Brit. M. J. 1: 1295-1298, 1954. CrossrefMedlineGoogle Scholar6. Risholm L: Acute upper alimentary tract ulcerations and hemorrhage following surgery or traumatic lesions, Acta chir. Scandinav. 110: 275-283, 1956. MedlineGoogle Scholar7. Griffiths HE: Trauma as a cause of chronic gastric ulcer, Lancet 2: 329-330, 1922. CrossrefGoogle Scholar8. Gray I: Trauma in relation to peptic ulcers, New York State J. Med. 45: 887-892, 1945. Google Scholar9. FletcherHarkins DGHN: Acute peptic ulcer as a complication of major surgery, stress, or trauma, Surgery 36: 212-226, 1954. MedlineGoogle Scholar10. Cushing H: Peptic ulcers and the interbrain, Surg., Gynec. and Obst. 55: 1-34, 1932. Google Scholar11. MastenBunts MGRC: Neurogenic erosions and perforations of the stomach and esophagus in cerebral lesions: report of six cases, Arch. Int. Med. 54: 916-930, 1934. CrossrefGoogle Scholar12. HoffSheehan ECD: Experimental gastric erosions following hypothalamic lesions in monkeys, Am. J. Path. 11: 789-802, 1935. MedlineGoogle Scholar13. OpperZimmerman LHM: Ulcers of the digestive tract in association with cerebral lesions, Yale J. Biol. and Med. 11: 49-84, 1938. MedlineGoogle Scholar14. Davidoff LM: Influences of nervous system on gastrointestinal tract, Rev. Gastroenterol. 11: 102-105, 1944. Google Scholar15. Strassman GE: Relation of acute mucosal hemorrhage and ulcers of the gastrointestinal tract to intracranial lesions, Arch. Neurol. and Psychiat. 57: 145-160, 1947. CrossrefMedlineGoogle Scholar16. WyattKhoo JPPN: Ulcers of the upper part of the gastrointestinal tract associated with acute damage of the brain, Arch. Path. 47: 110-118, 1949. Google Scholar17. GlobusRalston JB: Multiple erosions and acute perforations of the esophagus, stomach, and duodenum in relation to disorders of the nervous system, J. Mt. Sinai Hosp. 17: 817-842, 1951. MedlineGoogle Scholar18. FrenchPorterVon AmerongenRaney JRFR: Gastrointestinal hemorrhage and ulceration associated with intracranial lesions, Surgery 32: 395-407, 1952. MedlineGoogle Scholar19. Rockitansky C: Handbuch der speziellen pathologischen Anatomie. II Band, 1842, Broumüller and Seidel, Vienna. Google Scholar20. DoigShafar AJ: Gastric hemorrhage in acute intracranial vascular accidents, Quart. J. Med. 25: 1-19, 1956. MedlineGoogle Scholar21. WangensteenMerendinoLitow OHKASS: Hematemesis from erosion or ulcer (gastric and/or duodenal): an occasional complication of fracture, Bull. Am. Coll. Surgeons 30: 58, 1945. Google Scholar22. Silver PT: Fatal hemorrhage from a duodenal ulcer associated with a toxic adenoma of the thyroid gland, Canad. M. A. J. 15: 517-518, 1925. MedlineGoogle Scholar23. PennerBernheim AA: Acute postoperative esophageal, gastric and duodenal ulcerations: further study of pathological changes in shock, Arch. Path. 28: 129-140, 1939. Google Scholar24. Von EiselsbergPennerBernheim FAAI: Acute postoperative esophageal gastric and duodenal ulcerations, Arch. Path. 28: 129-140, 1939. Google Scholar25. Herbut PA: Acute peptic ulcers following distant operations, Surg., Gynec. and Obst. 80: 410-415, 1945. Google Scholar26. McDonnellMcCloskey WVJF: Acute peptic ulcers as a complication of surgery, Ann. Surg. 137: 67-74, 1953. CrossrefMedlineGoogle Scholar27. DryeSchoenSchuster JCAMG: Gastric secretion in the immediate postoperative period, Arch. Surg. 67: 469-474, 1953. CrossrefGoogle Scholar28. DavisWetzelDavis RANL: Acute upper alimentary tract ulceration and hemorrhage following neurosurgical operations, Surg., Gynec. and Obst. 100: 51-58, 1955. MedlineGoogle Scholar29. De Ruiter HJ: Acute gastrointestinal ulcers after operations, Nederl. tijdschr. v. geneesk. 99: 2186, 1955. MedlineGoogle Scholar30. Billroth T: Ueber Duodenalgeschwüre bei Septicämie, Wien. med. Wchnschr. 17: 705-709, 1867. Google Scholar31. Nichols HT: Mitral insufficiency—treatment by polar cross fusion of the annulus fibrosus, J. Thoracic Surg., in press. Google Scholar32. Selye H: The alarm reaction and the diseases of adaptation, Ann. Int. Med. 29: 403-415, 1948. LinkGoogle Scholar33. Hume DM: The role of the hypothalamus in the pituitary-adrenal cortical response to stress, J. Clin. Investigation 28: 790, 1949. Google Scholar34. GrayBensonReifensteinSpiro SJJARWHM: Chronic stress and peptic ulcer. I. Effect of corticotropin (ACTH) and cortisone on gastric secretion, J. A. M. A. 147: 1529-1537, 1951. CrossrefMedlineGoogle Scholar35. Moore FD: Bodily changes in surgical convalescence. I. The normal sequence—observations and interpretations, Ann. Surg. 137: 289-315, 1953. CrossrefMedlineGoogle Scholar36. ShaySun HDC: Stress and gastric secretion in man. I. A study of the mechanisms involved in insulin hypoglycemia, Am. J. M. Sc. 228: 630-642, 1954. CrossrefMedlineGoogle Scholar37. Shay H: Stress and gastric secretion, Editorial, Gastroenterology 26: 316-318, 1954. CrossrefMedlineGoogle Scholar38. Berkowitz D: Acute ulcerative lesions of the gastrointestinal tract following cardiac surgery—a pathological study, to be published. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Philadelphia, Pennsylvania*From the Symposium on Gastroduodenal Ulcer, presented at the Thirty-eighth Annual Session of The American College of Physicians, Boston, Massachusetts, April 11, 1957.From the Departments of Medicine and Thoracic Surgery, Hahnemann Medical College and Hospital, and the Bailey Thoracic Clinic, Philadelphia, Pennsylvania.Requests for reprints should be addressed to Donald Berkowitz, M.D., Temple University Hospital, Broad and Ontario Streets, Philadelphia 3, Pennsylvania. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byProspective Randomized Trial for Optimal Prophylactic Treatment of the Upper Gastrointestinal Complications After Open Heart SurgeryPathogenesis, risk factors, and incidence of upper gastrointestinal bleeding after cardiac surgery: Is specific prophylaxis in routine bypass procedures needed?Pathogenesis, risk factors, and incidence of upper gastrointestinal bleeding after cardiac surgery: Is specific prophylaxis in routine bypass procedures needed?Intraabdominal complications after cardiopulmonary bypassReview article : Gastrointestinal damage following cardiopulmonary bypassMassive upper gastrointestinal hemorrhage in an infant following cardiac surgeryPathologic Features of Gastrointestinal Tract Lesions in Childhood-Onset Systemic Lupus ErythematosusAbdominal complications following cardiopulmonary bypass in open-heart surgeryGastroduodenal perforation after open heart surgeryA major cause of gastrointestinal hemorrhage in patients with malignant diseaseGastrointestinal haemorrhages associated with urological diseasesOsservazioni Su Tre Casi Di Gastroenterorragie Secondarie a Interventi UrologiciHemorrhagic Necrosis of the Senile Endometrium (Apoplexia Uteri)Stress Ulcer: Etiology, Diagnosis and TreatmentHemorrhagic Necrosis of the Gastrointestinal Tract and Its Relation to Cardiovascular StatusMassive upper gastrointestinal hemorrhage after operationEndocrinopathies and peptic ulcerPulmonale und enterale Komplikationen nach Hirnsch�digungenGastric "Stress" Ulceration in Myocardial InfarctionAcute massive hemorrhage from peptic ulceration immediately following unrelated major surgeryMesenteric vascular insufficiencyEndocrine influences on the gastrointestinal tractThe Adrenal Glands and Peptic Ulcer�berblick �ber 1000 operierte MitralstenosenPresent Status of Endocrine Influences Upon the Stomach and their Relationship to Peptic Ulcer DiseaseHEMORRHAGIC DUODENITIS IN MYOCARDIAL INFARCTION*ALBERT M. KATZ, M.D.Akute Magen- und Zw�lffingerdarmgeschw�re nach Thoraxeingriffen 1 June 1957Volume 46, Issue 6Page: 1015-1023KeywordsCardiac surgeryCentral nervous systemGastrointestinal tractHemorrhageHospital medicineLesionsPeptic ulcersThoracic surgeryUlcers ePublished: 1 December 2008 Issue Published: 1 June 1957 Copyright & PermissionsCopyright ©, 1957, by The American College of PhysiciansPDF downloadLoading ...