ACROMEGALY, JEJUNAL ULCERS AND HYPERSECRETION OF GASTRIC JUICE: CLINICAL-PATHOLOGICAL CONFERENCE AT THE NATIONAL INSTITUTES OF HEALTH
Authors: C G ZUBROD, P WERMER, W PIEPER, T F HILBISH, R SMITH, T DUTCHER
Journal: Annals of Internal Medicine (1958)

Clinical-Pathological Conference1 December 1958ACROMEGALY, JEJUNAL ULCERS AND HYPERSECRETION OF GASTRIC JUICE: CLINICAL-PATHOLOGICAL CONFERENCE AT THE NATIONAL INSTITUTES OF HEALTHCHARLES G. ZUBROD, M.D., WILLIAM PIEPER, M.D., T. F. HILBISH, M.D., ROBERT SMITH, M.D., THOMAS DUTCHER, M.D., PAUL WERMER, M.D.CHARLES G. ZUBROD, M.D.Search for more papers by this author, WILLIAM PIEPER, M.D.Search for more papers by this author, T. F. HILBISH, M.D.Search for more papers by this author, ROBERT SMITH, M.D.Search for more papers by this author, THOMAS DUTCHER, M.D.Search for more papers by this author, PAUL WERMER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-49-6-1389 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptDr. Charles G. Zubrod: The presentation today, we hope, will be a contribution to our understanding of why tumors produce some of the effects they do. Dr. William Pieper, of the National Cancer Institute, will present the case.DR. WILLIAMPIEPER: This 45 year old male was first admitted to the Clinical Center in April, 1957, with acute complaints of recurrent abdominal pain, nausea and vomiting. History revealed that the patient was a known acromegalic giant (noted at age 16) who underwent pituitary radiation and partial hypophysectomy in 1947 at age 35 because of almost total blindness. His vision improved...Bibliography1. Morris H: Morris' Human anatomy; complete systematic treatise, edited by J. Parsons Schaeffer, 10th Ed., 1942, Blakiston Company, Philadelphia, p. 1635. Google Scholar2. MaimonBartlettHumphreysPalmer SNJPEMWL: Giant hypertrophic gastritis, Gastroenterology 8: 397, 1947. MedlineGoogle Scholar3. BalfourHightowerGambillWaughDockerty DCNCEEJMMB: Giant hypertrophy of gastric rugae (Menetrier's disease) associated with hypoproteinemia relieved only by total gastrectomy: report of case, Gastroenterology 16: 773, 1950. CrossrefMedlineGoogle Scholar4. CitrinSterlingHalsted YKJA: Mechanism of hypoproteinemia associated with giant hypertrophy of the gastric mucosa, New England J. Med. 257: 906, 1957. CrossrefMedlineGoogle Scholar5. KenneyDockertyWaugh FDMBJM: Giant hypertrophy of gastric mucosa: clinical and pathological study, Cancer 7: 671, 1954. CrossrefMedlineGoogle Scholar6. BrunschwigAllenOwensThornton AJGFMTF: Alloxan in treatment of insulin producing islet cell carcinoma of pancreas, J. A. M. A. 124: 212, 1944. CrossrefGoogle Scholar7. UnderdahlWoolnerBlack LOLBBM: Multiple endocrine adenomas: eight cases involving the parathyroids, pituitary, and pancreatic islets, J. Clin. Endocrinol. and Metabolism 13: 20, 1953. CrossrefGoogle Scholar8. Wermer P: Genetic aspects of adenomatosis of endocrine glands, Am. J. Med. 16: 363, 1954. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication October 9, 1958.This is an edited transcription of a clinical-pathological conference conducted at the Clinical Center, Bethesda, Maryland, by the National Cancer Institute, National Institutes of Health, Public Health Service, Department of Health, Education, and Welfare.Requests for reprints should be addressed to Charles G. Zubrod, M.D., National Institutes of Health, Bethesda 14, Maryland. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byMultiple Endocrine Neoplasia Type 1 and Zollinger-Ellison SyndromeSome Extrarenal Diseases Associated with Renal Stone or NephrocalcinosisMediastinal endocrine neoplasm in patients with multiple endocrine adenomatosis.A previously unrecognized associationMagenHYPERPARATHYROIDISM IN ACROMEGALY Findings in Three CasesThe Zollinger-Ellison Syndrome. Its Place in the Pathophysiology of Gastric Acid Secretion and of its Hormonal RegulationThe Endocrine System and the StomachTHE ZOLLINGER-ELLISON SYNDROME.Protracted effects of repeated doses of X-ray irradiation in ratsEndocrine Adenomatosis (Polyendocrine Disease) Familial OccurrencesDas Zollinger-Ellison-SyndromFAMILIAL ENDOCRINE ADENOMATOSIS WITH ULCEROGENIC TUMOUR OF THE PANCREASZollinger-Ellison Syndrome in a Bantu Woman, With Isolation of a Gastrin-Like Substance From the Primary and Secondary TumorsEndocrine Adenomas and Peptic Ulcer, with Special Reference to Pancreatic AdenomasPituitary Adenoma and Peptic Ulcer DiseaseMultiple Endocrine Adenoma Syndrome 1 December 1958Volume 49, Issue 6Page: 1389-1409KeywordsAdenomasHemorrhageMedical servicesNauseaPeptic ulcersPrevention, policy, and public healthThrombosisUlcersVisionVomiting ePublished: 1 December 2008 Issue Published: 1 December 1958 PDF downloadLoading ...