TREATMENT OF TUBERCULOUS MENINGITIS WITH A COMBINATION OF ISONICOTINIC ACID HYDRAZIDES, STREPTOMYCIN AND PARA-AMINOSALICYLIC ACID
Authors: E APPELBAUM, C ABLER
Journal: Annals of Internal Medicine (1957)

Article1 October 1957TREATMENT OF TUBERCULOUS MENINGITIS WITH A COMBINATION OF ISONICOTINIC ACID HYDRAZIDES, STREPTOMYCIN AND PARA-AMINOSALICYLIC ACIDEMANUEL APPELBAUM, M.D., F.A.C.P., CHARLES ABLER, M.D.EMANUEL APPELBAUM, M.D., F.A.C.P.Search for more papers by this author, CHARLES ABLER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-47-4-782 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn a previous paper1 by one of us (E. A.), the treatment of a series of cases of tuberculous meningitis with isonicotinic acid hydrazides alone was reported. The current paper is based on the use of a combination of isonicotinic acid hydrazides, streptomycin and para-aminosalicylic acid in 41 cases of tuberculous meningitis seen between March 6, 1952, and December 4, 1956.CLINICAL ASPECTSTable 1 shows the age distribution of the patients in this series. The youngest patient was seven months and the oldest 64 years of age. The wide range in age, with predominance of the younger age groups,...Bibliography1. AppelbaumAnderson ETA: Treatment of tuberculous meningitis with isonicotinic acid hydrazides, J. A. M. A. 156: 673, 1954. CrossrefMedlineGoogle Scholar2. King DS: Present status of the treatment of tuberculosis in man, J. A. M. A. 158: 829, 1955. MedlineGoogle Scholar3. PfuetzeDesautels KHEJ: Treatment of tuberculosis, Arch. Int. Med. 97: 99, 1956. CrossrefGoogle Scholar4. Wier JA: Present status of the treatment of tuberculosis, J. A. M. A. 162: 471, 1956. CrossrefMedlineGoogle Scholar5. 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VandiviereLoringMelvinWillis HMWEIS: The treated pulmonary lesion and its tubercle bacillus. II. The death and resurrection, Am. J. M. Sc. 232: 30, 1956. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*From the Symposium on the Treatment of Tuberculosis, presented at the Thirty-eighth Annual Session of The American College of Physicians, Boston, Massachusetts, April 10, 1957.From the Bureau of Laboratories, New York City Department of Health, and the Willard Parker and Sydenham Hospitals.Requests for reprints should be addressed to Emanuel Appelbaum, M.D., City of New York Department of Health, Bureau of Laboratories, Foot of East 15th Street, New York 9, N. Y. 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