STUDIES ON THE ETIOLOGY AND SERUM TREATMENT OF ENCEPHALITIS DURING THE EPIDEMIC IN NORTH DAKOTA AND MINNESOTA (1941)
Authors: Edward C. Rosenow, Hayes W. Caldwell
Journal: Annals of Internal Medicine (1942)

Article1 September 1942STUDIES ON THE ETIOLOGY AND SERUM TREATMENT OF ENCEPHALITIS DURING THE EPIDEMIC IN NORTH DAKOTA AND MINNESOTA (1941)EDWARD C. ROSENOW, M.D., HAYES W. CALDWELL, M.D.EDWARD C. ROSENOW, M.D.Search for more papers by this author, HAYES W. CALDWELL, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-17-3-474 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptWe have had opportunity to study the etiology of encephalitis as it occurred during the summer and autumn of 1941 and to observe patients while they were under treatment with the encephalitis antistreptococcic serum.CLINICAL STUDIESThe patients with encephalitis observed in this epidemic presented striking similarities in symptomatology and appearance. Headache, nausea and vomiting with fever were the cardinal symptoms. Patients who had the severe forms of the disease were striking in appearance; not infrequently the patients were irrational, many were lethargic and had lost sphincteric control of the bladder and rectum. Rational patients complained bitterly of severe headache...References1. ROSENOW EC: Poliomyelitis antistreptococcus serum; further studies on the bacteriology and serum treatment of poliomyelitis, Jr. Am. Med. Assoc., 1930, xciv, 777-784. CrossrefGoogle Scholar2. ROSENOW EC: The relation of streptococci to the epidemic of encephalitis in St. Louis; preliminary report, Proc. Staff Meet. Mayo Clin., 1933, viii, 559-563. Google Scholar3. ROSENOW EC: A method of staining microörganisms and their capsular substance, and its application to streptococci and to filtrates of the viruses and spinal fluids in poliomyelitis and encephalitis, Proc. Staff Meet. Mayo Clin., 1935, x, 115-121. Google Scholar4. ROSENOW EC: Recurring encephalomeningoradiculitis with fibromyositis following poliomyelitis; a bacteriologic study of sixty-four cases, Arch. Int. Med., 1939, lxiv, 1197-1221. CrossrefGoogle Scholar5. ROSENOWJACKSON ECGH: Microscopic demonstration of bacteria in the lesions of epidemic (lethargic) encephalitis, Jr. Infect. Dis., 1923, xxxii, 144-152. CrossrefGoogle Scholar6. ROSENOWSCHLOTTHAUER ECCF: Studies on the relation of streptococci to the etiology of equine encephalomyelitis: preliminary report, Proc. Staff Meet. Mayo Clin., 1937, xii, 631-636. Google Scholar7. MCKINLEYMECKACREE EBJSEG: Chemotherapy in virus diseases, Jr. Infect. Dis., 1939, lxiv, 36-42. CrossrefGoogle Scholar8. KELSON SR: Use of sulfanilamide (para amino benzene sulphonamide) in experimental poliomyelitis, Proc. Soc. Exper. Biol. and Med., 1937, xxxvi, 718-720. CrossrefGoogle Scholar9. ROSENOW EC: Failure of sulfapyridine to protect against experimental (virus) poliomyelitis, Proc. Staff Meet. Mayo Clin., 1939, xiv, 490-495. Google Scholar10. ROSENOW EC: Serologic specificity of streptococci having elective localizing power as isolated in various diseases of man, Jr. Infect. Dis., 1929, xlv, 331-359. CrossrefGoogle Scholar11. HELMHOLZROSENOW HFEC: Three cases of acute encephalitis treated with specific serum, Jr. Am. Med. Assoc., 1922, lxxix, 2068-2071. CrossrefGoogle Scholar12. ROSENOW EC: Specific serum treatment of epidemic (lethargic) encephalitis; further results, Jr. Am. Med. Assoc., 1923, lxxx, 1583-1588. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Rochester, Minnesota*Received for publication November 27, 1941.We are indebted to Dr. E. J. Larson, Jamestown, North Dakota, Dr. A. C. Baker, Fergus Falls, Minnesota, and their colleagues and to H. J. Larson, D. V. M., Fergus Falls, Minnesota, for their coöperation. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 September 1942Volume 17, Issue 3Page: 474-485KeywordsBladderEncephalitisEtiologyFallsFeversHeadachesNauseaRectumVomiting ePublished: 1 December 2008 Issue Published: 1 September 1942 PDF downloadLoading ...