Toxic Granulocytopenia, Purpura Hemorrhagica and Aplastic Anemia Following the Arsphenamines
Authors: Adolph B. Loveman
Journal: Annals of Internal Medicine (1932)

Article1 April 1932Toxic Granulocytopenia, Purpura Hemorrhagica and Aplastic Anemia Following the ArsphenaminesADOLPH B. LOVEMAN, A.B., M.D.ADOLPH B. LOVEMAN, A.B., M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-5-10-1238 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSenator77 in 1888 reported four fatal cases of acute infectious pharyngitis. Unfortunately no bacteriological or hematological studies were made. Fourteen years later Brown70 reported the first case of acute infectious pharyngitis with complete blood studies. The patient showed a marked leukopenia and on one occasion the polymorphonuclears were reduced to one per cent. From then until Schultz75 reported his cases of agranulocytic angina, examples of an agranulocytic blood picture were described by Schwartz,73 Türk,72 and Marchand.74As early as 1920, Moore and Foley7reported agranulocytic blood pictures following the arsphenamines. Since then many cases have been added to the literature....References1 ROHNERBALDRIDGEHANSMANN FJCWGH: Chronic benzene poisoning, Arch. Path. and Lab. Med., 1926, i, 221. Google Scholar2 LAWSONJACKSONCATTANACH GBWPGS: Arsenic poisoning, Jr. Am. Med. Assoc, 1925, lxxxv, 24. CrossrefGoogle Scholar3 ASKEY JM: Aplastic anemia due to benzol poisoning, Cal., and West. Med., 1928, xxix, 262. Google Scholar4 JENSEN J: Purpura hemorrhagica following neoarsphenamine, Minn. Med., 1929, xii, 689. Google Scholar5 KASTLIN GJ: Agranulocytic angina, Am. Jr. Med. Sci., 1927, clxxiii, 799. CrossrefGoogle Scholar6 O'LEARYCONNER PAHM: Acute purpura hemorrhagica as complication in treatment of syphilis, Am. Jr. Syph., 1925, ix, 262. 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Author, Article, and Disclosure InformationAffiliations: Ann Arbor, Michigan*Studies and contributions of the Department of Dermatology and Syphilology of the University of Michigan Medical School, service of Dr. Udo J. Wile.†Received for publication, July 28, 1931. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byChemical Agents Which Suppress Myelopoiesis: Agranulocytosis and LeukemiaToxische OsteopathienToxische OsteopathienHematologic Aspects of Arsenic IntoxicationBlutveränderungen bei Syphilis 1 April 1932Volume 5, Issue 10Page: 1238-1256KeywordsAnginaAplastic anemiaBloodDermatologyHematology and oncologyHemorrhagePharyngitis Issue Published: 1 April 1932 PDF downloadLoading ...