Albumin Administration in Patients With Sepsis
Authors: Libing Jiang, Yuefeng Ma, Mao Zhang
Journal: Annals of Internal Medicine (2015)

Letters17 February 2015Albumin Administration in Patients With SepsisLibing Jiang, MM, Yuefeng Ma, MD, PhD, and Mao Zhang, MD, PhDLibing Jiang, MMFrom Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.Search for more papers by this author, Yuefeng Ma, MD, PhDFrom Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.Search for more papers by this author, and Mao Zhang, MD, PhDFrom Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/L15-5051 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:In their network meta-analysis (NMA), Rochwerg and colleagues (1) concluded that albumin is superior to crystalloids and starches. However, their review did not include several studies that directly compare albumin with other fluids. Therefore, we did an updated meta-analysis based on a previous one (2).We excluded 6 studies by Dr. Joachim Boldt because of suspected lack of integrity and 3 studies that focused on the pediatric population. We also added 3 recently published studies (CRISTAL [Colloids Versus Crystalloids for the Resuscitation of the Critically Ill], EARSS [Early Albumin Resuscitation During Septic Shock], and ALBIOS [Albumin Italian ...References1. Rochwerg B, Alhazzani W, Sindi A, Heels-Ansdell D, Thabane L, Fox-Robichaud A, et al; Fluids in Sepsis and Septic Shock Group. Fluid resuscitation in sepsis: a systematic review and network meta-analysis. Ann Intern Med. 2014;161:347-55. [PMID: 25047428] doi:10.7326/M14-0178 LinkGoogle Scholar2. Delaney AP, Dan A, McCaffrey J, Finfer S. The role of albumin as a resuscitation fluid for patients with sepsis: a systematic review and meta-analysis. Crit Care Med. 2011;39:386-91. [PMID: 21248514] doi:10.1097/CCM.0b013e3181ffe217 CrossrefMedlineGoogle Scholar3. Caironi P, Tognoni G, Masson S, Fumagalli R, Pesenti A, Romero M, et al; ALBIOS Study Investigators. Albumin replacement in patients with severe sepsis or septic shock. N Engl J Med. 2014;370:1412-21. [PMID: 24635772] doi:10.1056/NEJMoa1305727 CrossrefMedlineGoogle Scholar4. Latour-Pérez J. New recommendations for the use of serum albumin in patients with severe sepsis and septic shock [Letter]. Crit Care Med. 2013;41:e289. [PMID: 24060790] doi:10.1097/CCM.0b013e31828ced28 CrossrefMedlineGoogle Scholar5. Lyu PF, Murphy DJ. Economics of fluid therapy in critically ill patients. Curr Opin Crit Care. 2014;20:402-7. [PMID: 24979711] doi:10.1097/MCC.0000000000000117 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Libing Jiang, MM; Yuefeng Ma, MD, PhD; Mao Zhang, MD, PhDAffiliations: From Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.Disclosures: Authors have disclosed no conflicts of interest. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterest Forms.do?msNum=L14-0523. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoFluid Resuscitation in Sepsis Bram Rochwerg , Waleed Alhazzani , Anees Sindi , Diane Heels-Ansdell , Lehana Thabane , Alison Fox-Robichaud , Lawrence Mbuagbaw , Wojciech Szczeklik , Fayez Alshamsi , Sultan Altayyar , Wang-Chun Ip , Guowei Li , Michael Wang , Anna Włudarczyk , Qi Zhou , Gordon H. Guyatt , Deborah J. Cook , Roman Jaeschke , and Djillali Annane , for the Fluids in Sepsis and Septic Shock GroupFluid Resuscitation in Sepsis Bram Rochwerg , Waleed Alhazzani , Anees Sindi , Diane Heels-Ansdell , Lehana Thabane , Alison Fox-Robichaud , Lawrence Mbuagbaw , Wojciech Szczeklik , Fayez Alshamsi , Sultan Altayyar , Wang-Chun Ip , Guowei Li , Michael Wang , Anna Włudarczyk , Qi Zhou , Gordon H. Guyatt , Deborah J. Cook , Roman Jaeschke , and Djillali Annane , for the Fluids in Sepsis and Septic Shock GroupAlbumin Administration in Patients With Sepsis Bram Rochwerg , Waleed Alhazzani , Roman Jaeschke , and Deborah J. Cook Albumin Administration in Patients With Sepsis Bram Rochwerg , Waleed Alhazzani , Roman Jaeschke , and Deborah J. Cook Metrics 17 February 2015Volume 162, Issue 4Page: 319KeywordsAlbuminsDeath ratesDisclosureMortalityNetwork analysisOdds ratioResuscitationSepsisShockStarches ePublished: 17 February 2015 Issue Published: 17 February 2015 Copyright & PermissionsCopyright © 2015 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...