THE CLINICAL SIGNIFICANCE OF THE Rh FACTOR WITH COMMENTS CONCERNING THE LABORATORY PROBLEMS
Authors: Roy R. Kracke, William R. Platt
Journal: Annals of Internal Medicine (1944)

Article1 April 1944THE CLINICAL SIGNIFICANCE OF THE Rh FACTOR WITH COMMENTS CONCERNING THE LABORATORY PROBLEMSROY R. KRACKE, M.D., WILLIAM R. PLATT, M.D.ROY R. KRACKE, M.D.Search for more papers by this author, WILLIAM R. PLATT, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-20-4-559 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn 1940, Landsteiner and Wiener1 discovered the existence of a new blood group factor in man following the injection of rabbits with the blood of the Macacus rhesus monkey. The serum of the immunized rabbits clumped not only the blood cells of the Rhesus monkeys but also the blood of about 85 per cent of human beings irrespective of their blood groups, thus revealing the presence in man of a new blood factor designated as Rh, because it was first found in the Rhesus monkey.Present knowledge of the Rh factor can be summarized as follows2: (a) it is an...Bibliography1. LANDSTEINERWIENER KAS: An agglutinable factor in human blood recognized by immune sera for rhesus blood, Proc. Soc. Exper. Biol. and Med., 1940, xliii, 223. CrossrefGoogle Scholar2. DAVIDSOHNTOBARSKY IB: The Rh blood factor, an antigenic analysis, Am. Jr. Clin. Path., 1942, xii, 434. CrossrefGoogle Scholar3. LEVINEWONG PH: The incidence of the Rh factor and erythroblastosis fetalis in Chinese, Am. Jr. Obst. and Gynec., 1943, xlv, 832. CrossrefGoogle Scholar4. WIENERPETERS ASHR: Hemolytic reactions following transfusions of blood of the homologous groups, with three cases in which the same agglutinogen was responsible, ANN. INT. MED., 1940, xiii, 2306. Google Scholar5. LEVINEBURNHAMKATZINVOGEL PLEMP: The rôle of isoimmunization in the pathogenesis of erythroblastosis fetalis, Am. Jr. Obst. and Gynec., 1941, xlii, 925. CrossrefGoogle Scholar6. MOLONEY WC: Personal communication, March 31, 1943. Google Scholar7. WITEBSKY E: Preparation and transfusion of safe universal blood, Jr. Am. Med. Assoc., 1941, cxvi, 2654. CrossrefGoogle Scholar8. WIENERSILVERMANARONSON ASIJW: Hemolytic transfusion reactions—prevention with special reference to a new biological test, Am. Jr. Clin. Path., 1942, xii, 241. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Emory University, Georgia*Read by the senior author before the Southeastern Sectional Meeting of the American College of Physicians, Jacksonville, Florida, May 26, 1943.From the Department of Pathology, Emory University School of Medicine, Emory University, Georgia. Nextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 April 1944Volume 20, Issue 4Page: 559-569KeywordsBloodBlood cellsBlood groupsRabbitsResearch laboratoriesRhesus ePublished: 1 December 2008 Issue Published: 1 April 1944 Copyright & PermissionsCopyright, 1944, by The American College of PhysiciansPDF downloadLoading ...