CYSTIC FIBROSIS OF THE PANCREAS IN YOUNG ADULTS
Authors: P A DI SANT'AGNESE, D H ANDERSEN
Journal: Annals of Internal Medicine (1959)

Editorial1 May 1959CYSTIC FIBROSIS OF THE PANCREAS IN YOUNG ADULTSPAUL A. di SANT'AGNESE, M.D., DOROTHY H. ANDERSEN, M.D.PAUL A. di SANT'AGNESE, M.D.Search for more papers by this author, DOROTHY H. ANDERSEN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-50-5-1321 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptI. INTRODUCTIONCystic fibrosis has only recently become a concern of adult medicine. It is a disease with a short history, introduced to clinical pediatrics in 1938, when three series of necropsied cases were reported independently by Andersen,1Harper2and Blackfan and May.3At that time three fourths of the patients died before the age of one year,1and only rarely did a child with the disease survive to school age. Clinical recognition became progressively more frequent, and at present few cases presenting at pediatric centers escape diagnosis. Until the end of World War II therapy by diet and sulfonamides...1 Andersen DH: Cystic fibrosis of the pancreas and its relation to celiac disease, Am. J. Dis. Child. 56: 344, 1938. CrossrefGoogle Scholar2 Harper M: Congenital steatorrhea due to pancreatic defect, Arch. Dis. Childhood 13: 45, 1938. CrossrefMedlineGoogle Scholar3 BlackfanMay KCD: Inspissation of secretion, dilatation of the ducts and acini, atrophy and fibrosis of the pancreas in infants, J. Pediat. 13: 627, 1938. CrossrefGoogle Scholar4 AndersenHodges DHRG: Celiac syndrome. V. Genetics of cystic fibrosis of the pancreas with a consideration of etiology, Am. J. Dis. Child. 72: 62, 1946. CrossrefMedlineGoogle Scholar5 GoodmanReed HOSC: Heredity of fibrosis of the pancreas: possible mutation rate of the gene, Am. J. Human Genet. 4: 59, 1952. MedlineGoogle Scholar6 Carter CO, in Bodian, M.: Fibrocystic disease of the pancreas, 1952, William Heinemann, London, p. 50. Google Scholar7 di Sant'Agnese PA: Recent observations on pathogenesis of cystic fibrosis of the pancreas, Pediatrics, in press. Google Scholar8 ShwachmanLeubnerCatzel HHP: Mucoviscidosis, Advances Ped. 7: 249, 1955. MedlineGoogle Scholar9 di Sant'Agnese PA: Cystic fibrosis of the pancreas, Am. J. Med. 21: 406, 1956. CrossrefMedlineGoogle Scholar10 Andersen DH: Cystic fibrosis of the pancreas, J. Chronic Dis. 7: 58, 1958. CrossrefMedlineGoogle Scholar11 di Sant'AgneseDarlingPereraShea PARCGAE: Abnormal electrolyte composition of sweat in cystic fibrosis of the pancreas, Pediatrics 12: 549, 1953. MedlineGoogle Scholar12 di Sant'Agnese PA: Fibrocystic disease of the pancreas, a generalized disease of exocrine glands, J. A. M. A. 160: 846, 1956. CrossrefMedlineGoogle Scholar13 McIntosh R: Cystic fibrosis of the pancreas in patients over 10 years of age, Acta pædiat. (Suppl. 100) 43: 469, 1954. CrossrefGoogle Scholar14 WestLevindi Sant'Agnese JRSMPA: Pulmonary function in cystic fibrosis of the pancreas, Pediatrics 13: 155, 1954. MedlineGoogle Scholar15 di Sant'AgneseBlanc PAWA: A distinctive type of biliary cirrhosis of the liver associated with cystic fibrosis of the pancreas: recognition through the signs of portal hypertension, Pediatrics 18: 387, 1956. MedlineGoogle Scholar16 SinnottDunnDobzhansky EWLLT: Principles of genetics, 1958, McGraw-Hill Book Co., Inc., New York. Google Scholar17 WoodFishmanReemstmaBarkerdi Sant'Agnese JAAPKHGPA: A comparison of sweat chlorides and intestinal fat absorption in chronic obstructive emphysema and fibrocystic disease of the pancreas, New England J. Med., in press. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *From the Departments of Pediatrics and Pathology, College of Physicians and Surgeons, Columbia University, and the Babies Hospital, New York, N. Y. 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DI SANT'AGNESE, M.D., WILLIAM O. JONES, M.D., ZACHARIAS DISCHE, M.D.PhänogenetikDie Pathologie der Verdauung und ResorptionInvolvement of Abdominal Organs in Cystic Fibrosis of the Pancreas 1 May 1959Volume 50, Issue 5Page: 1321-1330KeywordsCystic fibrosisDietHospital medicinePancreasPediatricsSulfonamideSurgeonsYoung adults ePublished: 1 December 2008 Issue Published: 1 May 1959 PDF downloadLoading ...