TYPE-SPECIFIC COLD AUTO-ANTIBODIES AS A CAUSE OF ACQUIRED HEMOLYTIC ANEMIA AND HEMOLYTIC TRANSFUSION REACTIONS: BIOLOGIC TEST WITH BOVINE RED CELLS
Authors: A S WIENER, L J UNGER, L COHEN, J FELDMAN
Journal: Annals of Internal Medicine (1956)

Article1 February 1956TYPE-SPECIFIC COLD AUTO-ANTIBODIES AS A CAUSE OF ACQUIRED HEMOLYTIC ANEMIA AND HEMOLYTIC TRANSFUSION REACTIONS: BIOLOGIC TEST WITH BOVINE RED CELLSA. S. WIENER, F.A.C.P., L. J. UNGER, L. COHEN, J. FELDMANA. S. WIENER, F.A.C.P., L. J. UNGER, L. COHEN, J. FELDMANAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-44-2-221 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe purpose of this report is to describe an unusual example of acquired hemolytic anemia in which cold auto-antibodies of extremely high titer were detected in the patient's serum. While similar cases have occasionally been reported in the past,1, 2, 3, 4, 5, 6the one to be described here exhibited certain important differences having fundamental significance. Previous experience had shown that such patients can generally be safely transfused with any blood of the homologous A-B-O group and Rh type, provided the blood is kept warm during the injection to prevent the cold auto-antibodies from reacting with the transfused cells....Bibliography1. DonathLandsteiner JK: Ueber paroxysmale Hämoglobinurie, München. med. Wchnschr. 51: 1590, 1904. Google Scholar2. McCombsMcElroy RJS: Reversible autohemagglutination with peripheral vascular symptoms, Arch. Int. Med. 59: 107, 1937. CrossrefGoogle Scholar3. Battaglia B: Hemolytic anemia complicating primary atypical pneumonia, with cold isohemagglutinins, Ann. Int. Med. 27: 469, 1947. LinkGoogle Scholar4. WienerSamwickMorrisonLoewe ASAAML: Acquired hemolytic anemia, Am. J. Clin. Path. 22: 301, 1952. CrossrefMedlineGoogle Scholar5. WienerGordonGallop ASEBC: Studies on autoantibodies in human sera, J. Immunol. 71: 58, 1953. MedlineGoogle Scholar6. Wiener AS: Blood groups and transfusion, 3d Ed., 1943, C. 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Author, Article, and Disclosure InformationAffiliations: *Received for publication October 21, 1955.From the Division of Immunohematology of the Jewish Hospital of Brooklyn, the Serological Laboratory of the Office of the Chief Medical Examiner of New York City, and the Blood and Plasma Bank of the New York University-Bellevue Medical Center. 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WIENER, M.D., F.A.C.P., EVE B. GORDON, ERICH RUSSOW, M.D. 1 February 1956Volume 44, Issue 2Page: 221-240KeywordsBiologicsBlood banksBlood cellsBlood plasmaCellsFibrinogenHemolytic anemiaResearch laboratories Issue Published: 1 February 1956 Copyright & PermissionsCopyright ©, 1956, by The American College of PhysiciansPDF downloadLoading ...