IDIOPATHIC HYPOPARATHYROIDISM AND IDIOPATHIC ADRENAL CORTICAL INSUFFICIENCY OCCURRING WITH CYSTIC FIBROSIS OF THE PANCREAS
Authors: F. Gilbert Mcmahon, David U. Cookson, J. D. Kabler, Stanley L. Inhorn
Journal: Annals of Internal Medicine (1959)

Case Reports1 August 1959IDIOPATHIC HYPOPARATHYROIDISM AND IDIOPATHIC ADRENAL CORTICAL INSUFFICIENCY OCCURRING WITH CYSTIC FIBROSIS OF THE PANCREASF. GILBERT MCMAHON, M.S., M.D., DAVID U. COOKSON, M.D., J. D. KABLER, M.D., STANLEY L. INHORN, M.D.F. GILBERT MCMAHON, M.S., M.D.Search for more papers by this author, DAVID U. COOKSON, M.D.Search for more papers by this author, J. D. KABLER, M.D.Search for more papers by this author, STANLEY L. INHORN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-51-2-371 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptWe have been able to find only two previously reported cases of concurrent idiopathic hypoparathyroidism and hypoadrenocorticalism with both clinical and autopsy confirmation.1, 2 Leifer and Hollander3 in 1953 and Papadatos and Klein4 in 1954 each reported instances of this duoglandular insufficiency, but autopsy data were not available. In two other instances of alleged hypoparathyroidism with Addison's disease,5, 6 the clinical data were incomplete and have subsequently been challenged.2, 3The case presented here is unique in that there is a lifelong history of mild to moderate steatorrhea which, on necropsy, proved to be due to cystic fibrosis of the...Bibliography1. Leonard MF: Chronic idiopathic hypoparathyroidism with superimposed Addison's disease in a child, J. Clin. Endocrinol. 6: 493-506, 1946. CrossrefGoogle Scholar2. PerlmutterEllisonNorsaKantrowitz MRRLAR: Idiopathic hypoparathyroidism and Addison's disease, Am. J. Med. 21: 634-643, 1956. CrossrefMedlineGoogle Scholar3. LeiferHollander EW: Idiopathic hypoparathyroidism and chronic adrenal insufficiency: a case report, J. Clin. Endocrinol. 13: 1264-1269, 1953. CrossrefGoogle Scholar4. PapadatosKlein CR: Addison's disease in a boy with hypoparathyroidism, J. Clin. Endocrinol. 14: 653-660, 1954. CrossrefGoogle Scholar5. TalbotButlerMacLachlan NBAMEA: The effect of testosterone and allied compounds on the mineral, nitrogen, and carbohydrate metabolism of a girl with Addison's disease, J. Clin. Investigation 22: 583-593, 1943. CrossrefMedlineGoogle Scholar6. SutphinAlbrightMcCune AFDJ: Five cases (three in siblings) of idiopathic hypoparathyroidism associated with moniliasis, J. Clin. Endocrinol. 3: 625-634, 1943. CrossrefGoogle Scholar7. KyleSchaafCanary LHMJJ: Phosphate clearance in the diagnosis of parathyroid dysfunction, Am. J. Med. 24: 240-248, 1958. CrossrefMedlineGoogle Scholar8. Andersen DH: Cystic fibrosis of the pancreas, J. Chron. Dis. 7: 58-90, 1958. CrossrefMedlineGoogle Scholar9. di Sant'Agnese PA: Cystic fibrosis of the pancreas, Am. J. Med. 21: 406-422, 1956. CrossrefMedlineGoogle Scholar10. Jackson WP: Steatorrhea and hypoparathyroidism, Lancet 1: 1086-1087, 1957. CrossrefGoogle Scholar11. CrispellParsonHamlinHollifield KRWJG: Addison's disease associated with histoplasmosis, Am. J. Med. 20: 23-29, 1956. CrossrefMedlineGoogle Scholar12. SalvesenBoe HAJ: Idiopathic hypoparathyroidism, Acta endocrinol. 14: 214-226, 1953. CrossrefMedlineGoogle Scholar13. SteinbergWaldron HBR: Idiopathic hypoparathyroidism: an analysis of fifty-two cases, including the report of a new case, Medicine 31: 133-154, 1952. CrossrefMedlineGoogle Scholar14. SutphinAlbrightMcCune AFDJ: Five cases of idiopathic hypoparathyroidism associated with moniliasis, J. Clin. Endocrinol. 3: 625-634, 1943. CrossrefGoogle Scholar15. TalbotSobelMcArthurCrawford NBEHJWJD: Functional endocrinology from birth through adolescence, 1952, Harvard University Press, Cambridge, Massachusetts. Google Scholar16. Case Records, Massachusetts General Hospital (40361), New England J. Med. 251: 442-448, 1954. CrossrefMedlineGoogle Scholar17. CraigSchiffBoone JMLHJE: Chronic moniliasis associated with Addison's disease, Am. J. Dis. Child. 89: 669-684, 1955. Google Scholar18. AlbrightReifenstein FEC: The parathyroid glands and metabolic bone disease, 1948, The Williams & Wilkins Co., Baltimore, Maryland, p. 95. Google Scholar19. VernerEngelMcPherson JVFLHT: Vitamin D intoxication: report of two cases treated with cortisone, Ann. Int. Med. 48: 765-773, 1958. LinkGoogle Scholar20. LitvakMoldawerForbesHenneman JMPAPPH: Hypocalcemic hypercalciuria during vitamin D and dihydrotachysterol therapy of hypoparathyroidism, J. Clin. Endocrinol. and Metabolism 18: 246-252, 1958. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication July 18, 1958.From the Departments of Medicine and Pathology, University of Wisconsin Medical School, Madison, Wisconsin.Requests for reprints should be addressed to F. Gilbert McMahon, M.D., Section of Medicine, Mahorner Clinic, 2030 St. Charles Avenue, New Orleans 13, Louisiana. 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