DIAGNOSTIC SIGNIFICANCE OF URINARY HORMONAL ASSAYS: REPORT OF EXPERIENCE WITH MEASUREMENTS OF 17-KETOSTEROIDS AND FOLLICLE STIMULATING HORMONE IN THE URINE
Authors: R F ESCAMILLA
Journal: Annals of Internal Medicine (1949)

Article1 February 1949DIAGNOSTIC SIGNIFICANCE OF URINARY HORMONAL ASSAYS: REPORT OF EXPERIENCE WITH MEASUREMENTS OF 17-KETOSTEROIDS AND FOLLICLE STIMULATING HORMONE IN THE URINEROBERTO F. ESCAMILLA, M.D., F.A.C.P.ROBERTO F. ESCAMILLA, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-30-2-249 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptHISTORYThe discovery that extracts of human urine have measurable androgenic and estrogenic effects has stimulated many investigators. Concepts worked out by years of clinical observations seemed possible of more definite proof or disproof. Estimating the values of excretion products of endocrine function in the urine promised a way to study further these established clinical syndromes in the human patient rather than in the experimental animal.However, bioassay is necessary in many of the determinations. This usually means maintaining animal colonies with all the attendant complications, and the necessity for specially trained personnel. Also various animal species do not react...Bibliography1. ZIMMERMANN W: Eine Farbreaktion der Sexualhormone und ihre Anwendung zur quantitativen colorimetrischen Bestimmung, Hoppe Seyler's Ztschr. f. physiol. Chem., 1935, ccxxxiii, 257-264. CrossrefGoogle Scholar2. INGRAM CH: 17-Ketosteroids—a review of the literature, Bull. Univ. Maryland School Med., 1946, xxxi, 63-70. Google Scholar3. ZONDEK B: Über die Hormone des Hypophysenvorderlappens. IV. Darstellung des Follikebreifungshormons (Prolan A)-Methodik der klinischen Harnanalyse zum Nachweis des Prolan, Klin. 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Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: San Francisco, California*Presented before the Twenty-ninth Annual Session of the American College of Physicians, San Francisco, California, April 21, 1948.From the Division of Medicine, University of California Medical School, San Francisco, California. Nextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe Role of Urine Investigations in Urology PracticeCLINICAL SIGNIFICANCE OF FSH EXCRETIONSIMMONDS' DISEASE AND ANOREXIA NERVOSAAcromegaly and Other Disorders of Growth Hormone Secretion Combined Clinical Staff Conference at the National Institutes of HealthJESSE ROTH, M.D., SEYMOUR M. GLICK, M.D., PEDRO CUATRECASAS, M.D., CHARLES S. HOLLANDER, M.D.ACTH and the corticosteroids in themanagement of allergic disorders in childrenPituitary and Adrenal Function in Undernutrition with Mental IllnessPseudohypoparathyroidism and HypothyroidismRAYMOND W. TURNER, M.D., TSUGISO TAKAMURA, M.D.Die Funktion der Nebennierenrinde bei Frauen mit Hirsutismus und Cyclusst�rungenAnorexia nervosa: Fact and theoryNiere und HarnAdrenal function in allergySimmonds' diseaseKrankheiten der SchilddrüseKrankheiten des KohlenhydratstoffwechselsThe Natural History, Treatment and Prognosis of Anorexia Nervosa, Based on a Study of 38 PatientsISOLATION AND DETERMINATION OF THE 17-KETOSTEROIDS IN URINEReactions to Heavy Physical Exertion and Thorn Tests in the Analysis of Physical Insufficiency SyndromesDie NebenniereADRENOCORTICAL TUMOURSBiochemie der Nebennierenrindensteroide und des ACTHUntersuchung der Körperflüssigkeiten und AusscheidungenDie Steroide beim Rheumatiker und ihre Ver�nderung durch TBIAdrenal Cortical Carcinoma in ChildrenHIRSUTISMA quantitative colorimetric method for certain ketosteroids using a modification of the Zimmerman reaction 1 February 1949Volume 30, Issue 2Page: 249-290KeywordsBioassays and physiological analysisEstrogensExcretionFollicle stimulating hormoneUrine ePublished: 1 December 2008 Issue Published: 1 February 1949 Copyright & PermissionsCopyright, 1949, by The American College of PhysiciansPDF downloadLoading ...