ACUTE INTERMITTENT PORPHYRIA IN IDENTICAL TWINS
Authors: Emmett L. Kehoe, Herman Rudensky, William W. Reynolds
Journal: Annals of Internal Medicine (1957)

Case Reports1 July 1957ACUTE INTERMITTENT PORPHYRIA IN IDENTICAL TWINSEMMETT L. KEHOE, HERMAN RUDENSKY, M.D., WILLIAM W. REYNOLDSEMMETT L. KEHOESearch for more papers by this author, HERMAN RUDENSKY, M.D.Search for more papers by this author, WILLIAM W. REYNOLDSSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-47-1-131 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIt is now well established that all types of porphyria are familial diseases in which the underlying mechanism is an inborn error of pigment metabolism. Patients with the condition often give histories suggestive of familial occurrence. Waldenstroem,1Turner,2Nesbitt3and other investigators have been able to trace the disease through two or three generations of a family. However, so far as can be ascertained from a review of the medical literature, the disease has never been reported in identical twins. In this report the case histories of indentical twins who developed symptoms of porphyria are described. The one who came...Bibliography1. Waldenström J: Studien ueber Porphyria, Acta med. Scandinav., Supp. 82: 1-254, 1937. Google Scholar2. Turner WJ: Acute idiopathic porphyria, Arch. Int. Med. 61: 762, 1938. CrossrefGoogle Scholar3. Nesbitt D: Acute porphyria, J. A. M. A. 124: 286-294 (Jan. 29) 1944. CrossrefGoogle Scholar4. Watson CJ: Porphyria metabolism, in Duncan, G. G.: Diseases of metabolism, 3d Ed., 1952, W. B. Saunders Co., Philadelphia, pp. 1079-1103. Google Scholar5. KehoeNewmanChandler ELSB: Acute porphyria, U. S. Armed Forces M. J. 4: 1119-1125 (Aug.) 1953. MedlineGoogle Scholar6. HalpernCopsey RMHG: Acute idiopathic porphyria, M. Clin. North America 30: 385-396 (Mar.) 1946. CrossrefMedlineGoogle Scholar7. OltmanFriedman JES: Acute porphyria, New England J. Med. 244: 173, 1951. CrossrefGoogle Scholar8. Becker I: The neuropsychiatric manifestations of porphyria, Am. Pract. and Digest. Treat. 2: 657-661 (Aug.) 1951. MedlineGoogle Scholar9. Markovitz M: Acute intermittent porphyria: a report of five cases and a review of the literature, Ann. Int. Med. 41: 1170-1188 (Dec.) 1954. LinkGoogle Scholar10. Kark R: Clinical aspects of major porphyrinopathies, M. Clin. North America 39: 11-30 (Jan.) 1955. CrossrefGoogle Scholar11. SchmidSchwartzWatson RSCJ: Porphyrin content of bone marrow and liver in the various forms of porphyria, Arch. Int. Med. 93: 167-190 (Feb.) 1954. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication January 9, 1956.Requests for reprints should be addressed to Emmett L. Kehoe, Colonel MC USA, Assistant Chief, Gastroenterology Service, Letterman Army Hospital, San Francisco, California. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySimultaneous manifestation of variegate porphyria in monozygotic twinsAcute intermittent porphyria in identical twins.Chromosomenveränderungen bei der akuten intermittierenden PorphyrieThe Porphyrias: A Genetic ProblemDigestive SystemAcetate Metabolism in Bovine, Fasting Ketosis 1 July 1957Volume 47, Issue 1Page: 131-140KeywordsHospital medicineInborn errors of metabolismMonozygotic twinsPorphyriaTwins ePublished: 1 December 2008 Issue Published: 1 July 1957 PDF downloadLoading ...