ACTIVE IMMUNIZATION AGAINST TETANUS
Authors: Herman Gold
Journal: Annals of Internal Medicine (1939)

Article1 November 1939ACTIVE IMMUNIZATION AGAINST TETANUSHERMAN GOLD, M.D.HERMAN GOLD, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-13-5-768 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptActive immunization against tetanus has aroused a great deal of interest among clinicians and public health workers because of its possible use as a preventive measure of general applicability. The antitoxin titer produced by the injection of tetanus toxoid, and the influence exerted upon this titer by such factors as dosage, time interval between injections, associated antigens and "repeat" or stimulating injection of toxoid, have been the subject of careful investigation.1-32 We now wish to add our findings on the comparative value of various antigenic preparations.Tetanus toxoid(plain) (No. 5969),tetanus toxoid(plain) to which 0.4 per cent alum...References1. DESCOMBEY P: Tetanus anatoxin, Compt.-rend. Soc. de biol., 1924, xci, 239. Google Scholar2. RAMONZOELLER GC: Tetanus anatoxin and active immunization of humans against tetanus, Ann. Inst. Pasteur, 1927, xli, 805. Google Scholar3. RAMONZOELLER GC: New results concerning human vaccination against tetanus, Compt.-rend. Soc. de biol., 1929, c, 92. Google Scholar4. RAMONZOELLER GC: On the value and duration of immunity conferred on humans by vaccination with tetanus antitoxin, Compt.-rend. Soc. de biol., 1933, cxii, 347. 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Active immunization of normal persons with tetanus toxoid, alum precipitated refined, Jr. Am. Med. Assoc., 1937, cix, 486. Google Scholar19. HALL WW: Active immunization against tetanus with tetanus toxoid, Mil. Surgeon, 1937, lxxx, 104. Google Scholar20. MCBRYDE A: Tetanus immunization with alum precipitated toxoid, South. Med. Jr., 1937, xxx, 565. CrossrefGoogle Scholar21. COWLES PB: Tetanus immunization, Yale Jr. Biol. and Med., 1937, ix, 409. Google Scholar22. JONESMOSS FGJM: Studies on tetanus toxoid. II. The response of human subjects to an injection of tetanus toxoid or tetanus alum precipitated toxoid one year after immunization, Jr. Immunol., 1937, xxxiii, 183. Google Scholar23. JONESMOSS FGJM: The antitoxic titers of human subjects following immunization with combined diphtheria and tetanus toxoids, alum precipitated, Jr. Immunol., 1937, xxxiii, 173. Google Scholar24. RAMON G: Tetanus toxoid and its use and value in immunization, Ann. de méd., 1937, xlii, 358. Google Scholar25. RAMON G: Tetanus immunity and influence of injections of stimulating adjuvant substances mixed with antigen, Rev. d'Immunol., 1937, iii, 193. Google Scholar26. GOLD H: Active immunization of allergic individuals against tetanus by means of tetanus toxoid, alum precipitated, refined, Jr. Allergy, 1938, ix, 545. CrossrefGoogle Scholar27. GOLD H: Active immunization against tetanus by means of tetanus toxoid, alum precipitated, refined, Jr. Lab. and Clin. Med., 1938, xxiii, 903. Google Scholar28. HAYDENHALL RWW: Active immunization against tetanus using alum precipitated toxoid, U. S. Nav. Med. Bull., 1938, xxxvi, 524. Google Scholar29. BOYD JS: Active immunization against tetanus, Jr. Roy. Army Med. Corps, 1938, lxx, 289. Google Scholar30. SACQUEPEÉPILODJUDE EMA: Antidiphtheric and antitetanic immunity in adults after associated triple revaccination against typho-paratyphoid fever, diphtheria and tetanus, Rev. d'Immunol., 1938, iv, 389. Google Scholar31. JONESMOSS FGJM: Combined diphtheria toxoid and tetanus toxoid, alum precipitated, Jr. Lab. and Clin. Med., 1939, xxiv, 512. Google Scholar32. GOLD H: On the value of a "repeat" injection of tetanus toxoid (secondary stimulus) in active immunization against tetanus, Jr. Lab. and Clin. Med. (to be published). Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Chester, Pa.*Received for publication February 28, 1939.†We wish to thank Dr. E. A. Whitney, Medical Director of The Elwyn Training School, Elwyn, Pa., for allowing us to use inmates of this institution for this study. All antigens and tests reported in this paper were obtained from, and performed by, the Technical Division, Mulford Biological Laboratories, Sharp and Dohme, Glenolden, Pa. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDie TetanusschutzimpfungL’immunisation active contre le tétanosImmunizationCombined ImmunizationsActive ImmunizationObservations on tetanus immunization: The dosage of alum-precipitated toxoid and the use of fluid toxoid after traumaActive immunization against tetanus by the combined subcutaneous and intranasal routes 1 November 1939Volume 13, Issue 5Page: 768-782KeywordsAntigensAntitoxinsPrevention, policy, and public healthTetanusToxoidsVaccination and immunization ePublished: 1 December 2008 Issue Published: 1 November 1939 PDF downloadLoading ...