SPONTANEOUS HEMOTHORAX IN HEMOPHILIA: CASE REPORT AND DISCUSSION OF THE HEMOPHILIA SYNDROMES, WITH REMARKS ON THE MANAGEMENT OF HEMOTHORAX
Authors: W R KAY, H G KUPFER
Journal: Annals of Internal Medicine (1957)

Case Reports1 July 1957SPONTANEOUS HEMOTHORAX IN HEMOPHILIA: CASE REPORT AND DISCUSSION OF THE HEMOPHILIA SYNDROMES, WITH REMARKS ON THE MANAGEMENT OF HEMOTHORAXWILLIAM R. KAY, M.D., F.A.C.P., HENRY G. KUPFER, M.D.WILLIAM R. KAY, M.D., F.A.C.P., HENRY G. KUPFER, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-47-1-152 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptHemorrhage, either spontaneous or following trauma, is the essential symptom of hemophilia. Joints are commonly involved, and epistaxis, bleeding following dental extractions, hematuria, bleeding from the gastrointestinal tract, and subcutaneous and intramuscular hemorrhages are frequently observed. Pulmonary and subpleural shadows thought to represent hemorrhage have been reported,1 but massive spontaneous bleeding into the pleural space as a manifestation of hemophilia is quite unusual.2True spontaneous hemothorax is to be differentiated from spontaneous pneumohemothorax. Most of the cases reported in the literature as spontaneous hemothorax have actually been cases of pneumohemothorax.3This latter condition is usually ascribed to the rupture of...Bibliography1. PendergrassNeuhauser EPEB: Pleural lesions in hemophilia, Am. J. Roentgenol. 48: 147, 1942. Google Scholar2. Wintrobe MW: Clinical hematology, 3rd Ed., 1951, Lea and Febiger, Philadelphia. Google Scholar3. BernsteinKloskParsonnet AEA: Spontaneous hemothorax, Dis. of Chest 12: 394, 1946. CrossrefMedlineGoogle Scholar4. FreedmanLevineSolis-Cohen PSL: Hemothorax in blood dyscrasias, Am. J. M. Sc. 205: 692, 1943. CrossrefGoogle Scholar5. Rosenthal RL: Hemophilia and hemophilia-like diseases caused by deficiencies in plasma thromboplastin factors, Am. J. Med. 17: 57, 1954. CrossrefMedlineGoogle Scholar6. BiggsDouglas RAS: The thromboplastin generation test, J. Clin. Path. 6: 23, 1953. CrossrefMedlineGoogle Scholar7. Rosenthal MC: Deficiency in plasma thromboplastin component, Am. J. Clin. Path. 28: 910, 1954. CrossrefGoogle Scholar8. JonesBigham PR: Spontaneous hemothorax with reference to the use of streptokinase and streptodornase, Ann. Int. Med. 39: 907, 1953. LinkGoogle Scholar9. CarrRobins DSG: Streptokinase and streptodornase in the treatment of clotted hemothorax, Ann. Surg. 133: 853, 1951. CrossrefMedlineGoogle Scholar10. DavidsonEpsteinMillerTaylor CRGF: Hemophilia. A clinical study of forty patients, Blood 4: 97, 1949. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Richmond, Virginia*Received for publication March 2, 1956.From the Departments of Medicine and Clinical Pathology, Medical College of Virginia Hospitals, Richmond, Virginia.Requests for reprints should be addressed to William R. Kay, M.D., Medical College of Virginia Hospital, 1200 East Broad Street, Richmond 19, Virginia. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byA rare case of spontaneous haemothorax in patient with haemophilia AHaemothorax in children with congenital coagulopathySpontaneous HemothoraxLife-Threatening Mediastinal-Retroperitoneal Hemorrhage in a Child With Moderate Hemophilia A and High Inhibitor TiterHematological DisordersThe Neck and ChestHemothorax in a ChildSpontaneous haemothorax in a mild haemophiliac.Hemothorax in idiopathic thrombocytopenic purpura (ITP)The antenatal background of blood diseases of infancy 1 July 1957Volume 47, Issue 1Page: 152-161KeywordsAdenosine triphosphateBlood plasmaClinical pathologyGastrointestinal tractHemophiliaHemorrhageHospital medicineLaboratory tests ePublished: 1 December 2008 Issue Published: 1 July 1957 PDF downloadLoading ...