ADENYLIC ACID IN HUMAN NUTRITION
Authors: Tom D. Spies, William B. Bean, Richard W. Vilter
Journal: Annals of Internal Medicine (1940)

Article1 March 1940ADENYLIC ACID IN HUMAN NUTRITIONTOM D. SPIES, M.D., F.A.C.P., WILLIAM B. BEAN, M.D., RICHARD W. VILTER, M.D.TOM D. SPIES, M.D., F.A.C.P.Search for more papers by this author, WILLIAM B. BEAN, M.D.Search for more papers by this author, RICHARD W. VILTER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-13-9-1616 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptFrom our studies of a large series of persons with mixed vitamin deficiency, we reported recently1, 2, 3that the diagnostic manifestations of pellagra, beriberi, riboflavin deficiency, vitamin A deficiency and vitamin B6deficiency respond to the administration of large amounts of synthetic nicotinic acid, thiamin hydrochloride, riboflavin, oleum percomorphum, and synthetic vitamin B6respectively. Each of these active chemical substances, in addition to its specific action for the relief of certain characteristic symptoms, promotes a general sense of well-being in these persons. Following the administration of crystalline vitamin supplements to their inadequate diets, the patients often became strong enough...Bibliography1. SPIESVILTERASHE TDRWWF: Pellagra, beriberi and riboflavin deficiency in human beings; diagnosis and treatment, Jr. Am. Med. Assoc., 1939, cxiii, 931. CrossrefGoogle Scholar2. SPIES TD: A note on the ocular symptoms occurring from malnutrition in human beings, Am. Jr. Med. Sci., 1939, cxcviii, 40. CrossrefGoogle Scholar3. SPIESBEANASHE TDWBWF: A note on the use of vitamin B6 in human nutrition, Jr. Am. Med. Assoc., 1939, cxii, 2414. CrossrefGoogle Scholar4. VILTERVILTERSPIES RWSPTD: Relationship between nicotinic acid and a codehydrogenase (cozymase) in blood of pellagrins and normal persons, Jr. Am. Med. Assoc., 1939, cxii, 420. CrossrefGoogle Scholar5. SYDENSTRICKERGEESLINTEMPLETONWEAVER VPLECMJW: Riboflavin deficiency in human subjects, Jr. Am. Med. Assoc., 1939, cxiii, 1697. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Cincinnati, Ohio*Received for publication December 16, 1939.From the Department of Internal Medicine, University of Cincinnati College of Medicine, and the Cincinnati General Hospital, Cincinnati, Ohio; and the Hillman Hospital, Birmingham, Alabama. These studies were aided by grants to the University of Cincinnati from the John and Mary R. Markle Foundation and Eli Lilly and Company.†Three preparations of adenylic acid were furnished through the courtesy of Anheuser Busch, Inc. and Merck and Company. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byEffect of adenylic acid therapy upon pruritus due to hodgkin'S and other diseasesAdenylic Acid in NutritionA METHOD FOR THE DETERMINATION OF ADENOSINE-5'-PHOSPHORIC ACID AND ITS HOMOLOGUES 1 March 1940Volume 13, Issue 9Page: 1616-1618KeywordsBeriberiDietHospital medicineNiacinNutritionRiboflavinThiamineVitamin A ePublished: 1 December 2008 Issue Published: 1 March 1940 PDF downloadLoading ...