PHAGOCYTIC RETICULOENDOTHELIAL CELLS IN SUBACUTE BACTERIAL ENDOCARDITIS WITH NEGATIVE CULTURES
Authors: R W HILL, E D BAYRD
Journal: Annals of Internal Medicine (1960)

Article1 February 1960PHAGOCYTIC RETICULOENDOTHELIAL CELLS IN SUBACUTE BACTERIAL ENDOCARDITIS WITH NEGATIVE CULTURESRICHARD W. HILL, M.D., EDWIN D. BAYRD, M.D.RICHARD W. HILL, M.D.Search for more papers by this author, EDWIN D. BAYRD, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-52-2-310 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSubacute bacterial endocarditis often presents a diagnostic problem. The patient with a history of valvular heart disease who experiences the insidious onset of intermittent fever, chills and sweats, signs of peripheral embolism, splenomegaly, and changing heart murmurs presents no such difficulty, and the diagnosis becomes obvious when the results of blood cultures are positive. It is the patient who has atypical findings and whose blood cultures repeatedly yield negative results who presents a difficult problem in evaluation and management.Subacute bacterial endocarditis with sterile blood cultures has been reviewed elsewhere.1-4However, the presence or absence of reticuloendothelial cells of the...Bibliography1. Keefer CS: Subacute bacterial endocarditis: active cases without bacteremia, Ann. Int. Med. 11: 714, 1937. LinkGoogle Scholar2. LoeweEiber LHB: Subacute bacterial endocarditis of undetermined etiology, Am. Heart J. 34: 349, 1947. CrossrefMedlineGoogle Scholar3. CatesChristie JERV: Subacute bacterial endocarditis: a review of 442 patients treated in 14 centres appointed by the Penicillin Trials Committee of the Medical Research Council, Quart. J. Med. 20: 93, 1951. MedlineGoogle Scholar4. Schultz R: The problem of subacute bacterial endocarditis with negative cultures, Journal-Lancet 77: 291, 1957. MedlineGoogle Scholar5. 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Pepper OH: The hematology of subacute Streptococcus viridans endocarditis, J. A. M. A. 89: 1377, 1927. CrossrefGoogle Scholar12. HeckConner FJHM: Unusual phagocytosis by reticular cells in the presence of a gram-negative bacillus in the blood, Proc. Staff Meet., Mayo Clin. 5: 358, 1930. Google Scholar13. ParsonsCooperScheifley WBTCH: Anemia in bacterial endocarditis, J. A. M. A. 153: 14, 1953. CrossrefMedlineGoogle Scholar14. Hagen H: Die Monomakrophagocytose als Symptom der Endocarditis lenta, Med. Klin. 51: 94, 1956. MedlineGoogle Scholar15. Cole JP: The significance of the phagocytic reticuloendothelial cell in blood smears from the ear in patients with subacute bacterial endocarditis, Thesis, Graduate School, University of Minnesota, 1951. Google Scholar16. DalandGottliebWallersteinCastle GALROWB: Hematologic observations in bacterial endocarditis: especially the prevalence of histiocytes and the elevation and variation of the white cell count in blood from the ear lobe, J. Lab. and Clin. Med. 48: 827, 1956. MedlineGoogle Scholar17. Joseph F: Hochgradige retikulo-endotheliale Monozytosen bei Endocarditis maligna, Deutsche med. Wchnschr. 51: 863, 1925. CrossrefGoogle Scholar18. Dameshek W: The appearance of histiocytes in the peripheral blood, Arch. Int. Med. 47: 968, 1931. CrossrefGoogle Scholar19. Connal A: Auto-erythrophagocytosis in protozoal diseases, J. Path. and Bact. 16: 502, 1911. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Rochester, Minnesota*Received for publication March 30, 1959.From the Section of Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minnesota.The Mayo Foundation is a part of the Graduate School of the University of Minnesota.Requests for reprints should be addressed to Section of Publications, Mayo Clinic, Rochester, Minnesota. 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GREENBERG, M.D.BACTERIAL ENDOCARDITIS IN SYDNEY 1950‐1959 1 February 1960Volume 52, Issue 2Page: 310-319KeywordsBacterial culturesBloodCellsEndocarditisGraduate medical educationHeart murmursPhagocytosisSplenomegalySweatUrea ePublished: 1 December 2008 Issue Published: 1 February 1960 PDF downloadLoading ...