THE ASSOCIATION OF POLYCYTHEMIA VERA AND PEPTIC ULCER
Authors: Dwight L. Wilbur, Harold C. Ochsner
Journal: Annals of Internal Medicine (1935)

Article1 June 1935THE ASSOCIATION OF POLYCYTHEMIA VERA AND PEPTIC ULCERDWIGHT L. WILBUR, M.D., HAROLD C. OCHSNER, M.D.DWIGHT L. WILBUR, M.D.Search for more papers by this author, HAROLD C. OCHSNER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-8-12-1667 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptOur interest was aroused in the significance of the association of duodenal ulcer and polycythemia vera as a result of observation of a patient who had both diseases. A review of the literature revealed interesting speculations in regard to the association of these conditions because of recent demonstrations of the relation of gastric secretion and hematopoietic function. It seemed reasonable that with the large amount of material available at this clinic some conclusions might be drawn as to the incidence of association of these diseases.In the available medical textbooks, the gastrointestinal symptoms associated with polycythemia vera are minimized. Osler1...Bibliography1. OSLERMCCRAE WT: Modern medicine, 1915, iv, 684, Lea and Febiger, Philadelphia. Google Scholar2. VAQUEZ H: Hyperglobulie et splénomégalie, Bull. et mém. Soc. med. d. hôp. d. Par., 1899, xvi, 579-582. Google Scholar3. WEBERWATSON FPJH: Chronic polycythemia with enlarged spleen (Vaquez disease) probably a disease of the bone marrow, Internat. Clin., 1905, iv, 47-66. Google Scholar4. SCHNEIDER N: Ein Beitrag zur Frage der Polyglobulie, Wien. klin. Wchnschr., 1907, xx, 413-418. Google Scholar5. GIFFIN HZ: Personal communication to the authors. Google Scholar6. FRIEDMAN GA: A hitherto undescribed form of polycythemia and its possible relation to duodenal ulcer, chronic pancreatitis, and a disturbance of internal secretions (adrenalin), Med. Rec., 1913, lxxxiv, 701-710. Google Scholar7. FRIEDMAN GA: The value of polycythemia for the diagnosis of duodenal ulcer, based upon sixteen operatively demonstrated cases, Med. Rec., 1914, lxxxv, 875-881. Google Scholar8. NAEGELI O: Blutkrankheiten und Blutdiagnostik. Lehrbuch der klinischen Hämatologie, 1931, v, 577, Julius Springer, Berlin. CrossrefGoogle Scholar9. BING NJ: Polycythemia in juxtapyloric ulcer, Ugesk. f. Laeger., 1920, lxxxii, 337. (Abstr., Brit. Med. Jr., 1920, i, 625.) Google Scholar10. HIRSCHFELD H: Lehrbuch der Blutkrankheiten für Aerzte und Studierende, 1918, pp. 54-55, A. Hirschwald, Berlin. CrossrefGoogle Scholar11. TUCHFELD F: Ulcus duodeni und Polyglobulie. Zur Frage: Magenfunktion und rotes Blutbild, Med. Klin., 1931, xxvii, 130-131. Google Scholar12. MORRIS RS: Erythremia—a therapeutic suggestion, Jr. Am. Med. Assoc., 1933, ci, 200-201. CrossrefGoogle Scholar13. OERTINGBRIGGS HJF: The influence of gastric lavage on familial and non-familial erythremia, Jr. Am. Med. Assoc., 1935, civ, 250. Google Scholar14. BOYD W: The relationship of polycythemia to duodenal ulcer, Am. Jr. Med. Sci., 1934, clxxxvii, 589-594. CrossrefGoogle Scholar15. ALLODIGRIVA AL: Ricerche ematologiche im affezioni del tratto gastro-intestinale accompagnantisi ad iperaciditá, Minerva Med., 1930, ii, 221-226. Google Scholar16. BROWNGIFFIN GEHZ: The treatment of polycythemia vera (erythremia) with phenylhydrazine, Arch. Int. Med., 1926, xxxviii, 321-345. CrossrefGoogle Scholar17. GIFFINALLEN HZEV: Control and complete remission of polycythemia vera following the prolonged administration of phenylhydrazine hydrochloride, Am. Jr. Med. Sci., 1933, clxxxv, 1-13. Google Scholar18. HARTMAN HR: La frecuencia con que se presentan las ulceras gastricas y duodenales en la clinica Mayo, Caceta Medica de Mexico, 1934, lxv, 111-120. Google Scholar19. OCHSNER HC: Unpublished observations. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Rochester, Minnesota*Submitted for publication March 4, 1935.From the Division of Medicine, The Mayo Clinic, Rochester, Minn. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byGastroduodenal lesions in polycythaemia vera: frequency and role of Helicobacter pyloriBasophilic leukemia and the hypersecretion of gastric acid and pepsinBASOPHILS, HISTAMINE AND GASTRIC ACID SECRETIONSBasophils, histamine and gastric acid secretion in chronic myeloproliferative disordersPeptisches UlcusMagenDie Therapie der Polycythaemia rubra vera Vaquez-OslerDie Therapie der Polycythaemia rubra vera Vaquez-OslerGastric Secretory Function in Polycythaemia VeraPolycythemiaThe Circulation of the StomachExtragastric factors associated with peptic ulcerLeukaemic lesions of the gastrointestinal tractEffect of polycythemia on gastric secretionPOLYCYTHÆMIA VERAGastric pepsin secretion and ABO blood groups in polycythemia veraPOLYCYTHEMIA VERA. II. COURSE AND THERAPY*PAUL CALABRESI, M.D., OVID O. MEYER, M.D., F.A.C.P.FATAL POLYCYTHEMIA FOLLOWING PERNICIOUS ANEMIA TREATED WITH VITAMIN B12*CARL F. HINZ JR., M.D.THE COINCIDENCE OF BENIGN GASTRIC ULCER AND CHRONIC PULMONARY DISEASE*JOHN M. WEBER, M.D., LUCIEN A. GREGG, M.D., F.A.C.P.Polyglobulie avec stase papillaireAbdominal Masses. V. Systemic Diseases and Diseases of Special Regions: Chronic Myelogenous Leukemia, Chronic Lymphatic Leukemia, Lymphosarcoma, Polycythemia Vera, Tumors of the Abdominal Wall, and Retroperitoneal TumorsPolycythaemia Vera. Course and Prognosis1Die Erkrankungen des erythrocytären Systems 1 June 1935Volume 8, Issue 12Page: 1667-1672KeywordsDuodenal ulcersPeptic ulcersPolycythemia vera ePublished: 1 December 2008 Issue Published: 1 June 1935 PDF downloadLoading ...