Treatment of Community-Acquired Methicillin-Resistant <i>Staphylococcus aureus</i> Infection
Authors: Henry M. Blumberg, Susan M. Ray, Mark D. King
Journal: Annals of Internal Medicine (2006)

Letters1 August 2006Treatment of Community-Acquired Methicillin-Resistant Staphylococcus aureus InfectionHenry M. Blumberg, MD, Susan M. Ray, MD, and Mark D. King, MD, MScHenry M. Blumberg, MDFrom Emory University School of Medicine, Atlanta, GA 30303, and Beacon Clinic, Boulder, CO 80304.Search for more papers by this author, Susan M. Ray, MDFrom Emory University School of Medicine, Atlanta, GA 30303, and Beacon Clinic, Boulder, CO 80304.Search for more papers by this author, and Mark D. King, MD, MScFrom Emory University School of Medicine, Atlanta, GA 30303, and Beacon Clinic, Boulder, CO 80304.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-145-3-200608010-00018 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE: We thank Drs. de Almeida and Bush and Dr. Johnson for their interest in our study, which demonstrated that the MRSA USA 300 clone has emerged as the predominant cause of community-onset skin and soft-tissue infections (accounting for nearly two thirds of all such infections) in urban Atlanta, Georgia. Our findings have important consequences for empirical antibiotic selection in these cases. Vancomycin is now the preferred choice for empirical therapy for patients with severe skin and soft-tissue infections who require admission to Grady Memorial Hospital in Atlanta, pending results of culture and susceptibility tests. Newer agents for the ...References1. Stevens DL, Herr D, Lampiris H, Hunt JL, Batts DH, Hafkin B. Linezolid versus vancomycin for the treatment of methicillin-resistant Staphylococcus aureus infections. Clin Infect Dis. 2002;34:1481-90. [PMID: 12015695] CrossrefMedlineGoogle Scholar2. Moellering RC. The growing menace of community-acquired methicillin-resistant Staphylococcus aureus [Editorial]. Ann Intern Med. 2006;144:368-70. [PMID: 16520479] LinkGoogle Scholar3. Gorwitz RJ, Jernigan DB, Powers JH, Jernigan JA, and Participants in the Centers for Disease Control and Prevention-Convened Experts' Meeting on Management of MRSA in the Community. Strategies for clinical management of MRSA in the community: summary of an experts' meeting convened by the Centers for Disease Control and Prevention. March 2006. Accessed at www.cdc.gov/ncidod/dhqp/pdf/ar/CAMRSA_ExpMtgStrategies.pdf on 9 June 2006. Google Scholar4. Ruhe JJ, Monson T, Bradsher RW, Menon A. Use of long-acting tetracyclines for methicillin-resistant Staphylococcus aureus infections: case series and review of the literature. Clin Infect Dis. 2005;40:1429-34. [PMID: 15844065] CrossrefMedlineGoogle Scholar5. Johnson JR. Linezolid versus vancomycin for methicillin-resistant Staphylococcus aureus infections [Letter]. Clin Infect Dis. 2003;36:236-7. [PMID: 12522761] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Emory University School of Medicine, Atlanta, GA 30303, and Beacon Clinic, Boulder, CO 80304.Disclosures: None disclosed. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoEmergence of Community-Acquired Methicillin-Resistant Staphylococcus aureus USA 300 Clone as the Predominant Cause of Skin and Soft-Tissue Infections Mark D. King , Bianca J. Humphrey , Yun F. Wang , Ekaterina V. Kourbatova , Susan M. Ray , and Henry M. Blumberg The Growing Menace of Community-Acquired Methicillin-Resistant Staphylococcus aureus Robert C. Moellering Jr. Treatment of Community-Acquired Methicillin-Resistant Staphylococcus aureus Infection Kleper N.F. de Almeida and Larry M. Bush Treatment of Community-Acquired Methicillin-Resistant Staphylococcus aureus Infection James R. Johnson Metrics 1 August 2006Volume 145, Issue 3Page: 232-233KeywordsClinical trialsDoxycyclineInfectious disease controlInfectious diseasesMethicillin-resistant Staphylococcus aureusOutpatientsSkin infectionsStaphylococcal infectionTetracyclinesVancomycin ePublished: 1 August 2006 Issue Published: 1 August 2006 CopyrightCopyright © 2006 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...