COEXISTING MYXEDEMA AND CHRONIC PLUMBISM
Authors: H U KREMER, M N FRANK
Journal: Annals of Internal Medicine (1955)

Case Reports1 May 1955COEXISTING MYXEDEMA AND CHRONIC PLUMBISMHOWARD U. KREMER, M.D., MARTIN N. FRANK, M.D.HOWARD U. KREMER, M.D.Search for more papers by this author, MARTIN N. FRANK, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-42-5-1130 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThis case is being presented because the apparent diversity of clinical findings and the question of multiple etiologic factors created a diagnostic problem. We believe it quite unusual to note objective evidence of activity of lead intoxication some 36 years following exposure to this heavy metal. The coexisting myxedema lends further interest.CASE REPORTA 70 year old white male cabinetmaker was admitted to the medical wards of the Philadelphia General Hospital on April 13, 1950, for anemia and weakness. This was his sixth admission; previous admissions had been required for anemia, weakness and angina pectoris.Physical examination disclosed a...Bibliography1. AubFairhallMinotReznikoff JCLJASP: Lead poisoning, Medicine 4: 1-25 (Feb.) 1928. Google Scholar2. Bomford R: Anemia in myxedema and the role of the thyroid gland in erythropoiesis, Quart. J. Med. 7: 495-536 (Oct.) 1938. Google Scholar3. Brookfield RW: Blood changes occurring during the course of treatment of malignant disease by lead, J. Path. and Bact. 31: 277, 1928. CrossrefGoogle Scholar4. Davidson LS: Macrocytic hemolytic anemia, Quart. J. Med. 1: 543, 1932. Google Scholar5. GrinsteinKoffDeMelbWatson MWHMRRCJ: The biosynthesis of coproporphyrin III in experimental lead poisoning, J. Biol. Chem. 182: 723, 1950. CrossrefGoogle Scholar6. KetyLetonoff STV: Treatment of lead poisoning by sodium citrate, Am. J. M. Sc. 205: 406-414 (Mar.) 1943. CrossrefGoogle Scholar7. LetonoffReinhold TVJG: Colorimetric determination of lead Chromate by diphenylcarbazide, Ind. and Eng. Chemistry-Analytical Edition 12: 280, 1940. CrossrefGoogle Scholar8. McFadden AJ: On the nature and significance of stippling in lead poisoning with reference to the effect of splenectomy, Quart. J. Med. 18: 57, 1948. Google Scholar9. Porritt N: Cumulative effects of infinitesimal doses of lead, Brit. M. J. 2: 92-94 (July) 1931. CrossrefMedlineGoogle Scholar10. ReznikoffAub PJC: Lead studies. XIV. Experimental studies of lead palsy, Arch. Neurol. and Psychiat. 27: 444, 1927. CrossrefGoogle Scholar11. RiggsLetonoffReinhold HTVJG: Tissue lead concentrations in disease, Am. J. Clin. Path. 14: 175, 1944. CrossrefGoogle Scholar12. SmithRathwellMascil FLTKCE: Lead poisoning test, in Cyclopedia of medicine, surgery and specialties, 1939, F. A. Davis Co., Philadelphia, pp. 811-837. Google Scholar13. TrumperCantarow MA: Lead poisoning, 1944, The Williams and Wilkins Co., Baltimore. Google Scholar14. Watson CJ: The erythrocyte coproporphyrin, Arch. Int. Med. 86: 797, 1950. CrossrefGoogle Scholar15. Brain WR: Diseases of the nervous systems, 1951, Oxford University Press, New York. Google Scholar16. Wintrobe MM: Clinical hematology, 1953, Lea and Febiger, Philadelphia. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Philadelphia, Pennsylvania*Received for publication May 21, 1954.From the Medical Wards of Philadelphia General Hospital. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byA meta-analysis of studies investigating the effects of occupational lead exposure on thyroid hormonesThyroid function in pekin ducklings as a consequence of erosion of ingested lead shot 1 May 1955Volume 42, Issue 5Page: 1130-1136KeywordsAnemiaAnginaCalciumExcretionHeavy metalsIntoxication ePublished: 1 December 2008 Issue Published: 1 May 1955 PDF downloadLoading ...