PARENTERAL USE OF THE SULFONAMIDES
Authors: LYNN T. HALL
Journal: Annals of Internal Medicine (1942)

Article1 November 1942PARENTERAL USE OF THE SULFONAMIDESA CLINICAL AND EXPERIMENTAL STUDY*LYNN T. HALL, M.D., F.A.C.P., EDWARD THOMPSON, M.D., RAYMOND J. WYRENS, M.D., ALBERT M. HARRIS, M.D., VIOLET WILDER, PH.D.LYNN T. HALL, M.D., F.A.C.P.Search for more papers by this author, EDWARD THOMPSON, M.D.Search for more papers by this author, RAYMOND J. WYRENS, M.D.Search for more papers by this author, ALBERT M. HARRIS, M.D.Search for more papers by this author, VIOLET WILDER, PH.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-17-5-835 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe efficacy of the sulfonamide drugs in the treatment of many infections is generally accepted. The Council on Pharmacy and Chemistry has listed certain sulfonamides, stating their action, use, toxicity, and general status. It must be emphasized, however, that these chemicals are still relatively new and, therefore, require further experimental study in some phases of their behavior. At present in the United States, oral or intravenous administration is favored, although in England1, 2and Canada3the intramuscular route is also used. We have studied the rapidity of absorption and secretion of the sulfonamide drugs, the degree of acetylation, and toxic...Bibliography1. GAISFORDEVANSWHITELAW WFGMW: Parenteral therapy with M. and B. 693, Lancet, 1939, ii, 69. CrossrefGoogle Scholar2. BANKS HS: Chemotherapy of meningococcal meningitis, Lancet, 1939, ii, 921. CrossrefGoogle Scholar3. BROWNTHORNTONWILSON WHWBJS: Observations on the absorption, distribution, and excretion of sulfapyridine, Dagenan, or M. and B. 693, Jr. Clin. Invest., 1939, xviii, 803. CrossrefGoogle Scholar4. HALLTHOMPSONWYRENS LTCERJ: Intramuscular administration of sodium sulfapyridine, Jr. Lab. and Clin. Med., 1940, xxvi, 314. Google Scholar5. THOMPSON CE: Parenteral use of sulfapyridine, Read before the Omaha Mid-West Clinical Society, Omaha, October 30, 1940. Google Scholar6. BARLOWCLIMENKO OWDR: Studies on the pharmacology of sulfapyridine and sulfathiazole: absorption of free acid, sodium salt and glucoside from alimentary tract, Jr. Am. Med. Assoc., 1941, cxvi, 282. CrossrefGoogle Scholar7. REINHOLDFLIPPINSCHWARTZ JGHFL: Observations on the pharmacology and toxicology of sulfathiazole in man, Am. Jr. Med. Sci., 1940, cxcix, 393. CrossrefGoogle Scholar8. STRAUSSLOWELLTAYLORFINLAND EFCFHM: Observations on the absorption, excretion and distribution of sulfanilamide, sulfapyridine, sulfathiazole, and sulfamethylthiazole, ANN. INT. MED., 1941, xiv, 1360. Google Scholar9. STRICKLERMCGINTYPESCHAW CWAPJB: The intravenous use of sodium sulfapyridine in the treatment of lobar pneumonia, ANN. INT. MED., 1941, xiv, 1595. Google Scholar10. MARSHALLLONG EKPH: The intravenous use of sodium sulfapyridine, Jr. Am. Med. Assoc., 1939, cxii, 1671. CrossrefGoogle Scholar11. FRANKLAND AW: Dangers of sulfapyridine, Brit. Med. Jr., 1940, ii, 682. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: LYNN T. HALL, M.D., F.A.C.P.; EDWARD THOMPSON, M.D.; RAYMOND J. WYRENS, M.D.; ALBERT M. HARRIS, M.D.; VIOLET WILDER, PH.D.Affiliations: Omaha, Nebraska*Received for publication February 4, 1942.From the University of Nebraska, College of Medicine, Department of Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 November 1942Volume 17, Issue 5 Page: 835-841 Keywords Behavior Drug absorption Drugs Sulfonamide Toxicity ePublished: 1 December 2008 Issue Published: 1 November 1942 PDF downloadLoading ...