tbuckley/cabot-search huggingface dataset:
The Significance Of Abnormal Metabolic Features In The Management Of Thyrotoxicosis
Authors: Walter B. Palmer
Journal: Annals of Internal Medicine (1930)

Article1 January 1930The Significance Of Abnormal Metabolic Features In The Management Of ThyrotoxicosisWALTER B. PALMERWALTER B. PALMERAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-3-7-651 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe management of the thyrotoxicoses is a popular topic for medical meetings and medical journals. During the past few years scores of articles dealing with this phase of the thyroid problem have appeared. Generally the authors are on the defensive, advocating either surgical or medical treatment. At the outset I wish to make it clear that this is not my intention. Many clinicians prefer to postpone surgery until all medical measures have proved of no avail. In some of the hospitals a case of exophthalmic goiter is seldom if ever seen on the medical services, while in others the medical...References:1 STURGISZUBIRANWELLSBADGER CCSGWT, J. Clin. Invest., 1926, ii, 289. CrossrefGoogle Scholar2 PALMERCARSONSLOAN WWDALW, J. Clin. Invest., Vol. VI No. 4, February 20, 1929, 597. CrossrefGoogle Scholar3 FISKESUBBARROW CHY, Science, 1927, lxv, 401. CrossrefGoogle Scholar4 EGGLESTONEGGLESTON PGP, Biochem. J., 21, 190, 1927. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York*Presented at the Boston Meeting of the American College of Physicians, April 11, 1929. Nextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byInnere SekretionDie Basedowsche Krankheit 1 January 1930Volume 3, Issue 7Page: 651-657KeywordsMedical servicesSurgeryThyroid ePublished: 1 December 2008 Issue Published: 1 January 1930 PDF downloadLoading ...
Group Drafts Core Curriculum for ‘What Docs Need to Know About Genetics'
Authors: J Stephenson
Journal: JAMA (1998)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Working with AIDS Bereavement: A Comprehensive Approach for Mental Health Providers
Authors: Brian Kelly
Journal: BMJ (2001)

Peter B Goldblum, Sarah Erickson 

UCSF AIDS Health Project, $10.95, pp 100

ISBN 1 879168 03 0

Rating: ![Graphic][1]  ![Graphic][2]  ![Graphic][3] 

AIDS had a profound impact on all communities towards the end of the 20th century. Although the advances in antiretroviral treatment have given hope for longer term survival for those infected with HIV, the psychological and social impact of the disease remains profound.

This new publication, from the UCSF AIDS Health Project HIV Research Group, is a valuable and pertinent reminder of the impact of HIV related bereavement and of the interventions that can …

 [1]: /embed/inline-graphic-1.gif
 [2]: /embed/inline-graphic-2.gif
 [3]: /embed/inline-graphic-3.gif
Vanitas Still Life
Authors: M. Therese Southgate
Journal: JAMA (2000)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
On target for health?
Authors: M. McKee
Journal: BMJ (2000)

Twenty years ago asking a health minister what he or she wanted to achieve would probably have elicited a response based on inputs, such as the number of new hospital beds opened or the amount spent on health care. Although some ministers might still give such a response, the focus is shifting to outcomes rather than inputs.

One feature of this shift is the development of health targets. In 1984 the World Health Organisation's office for Europe launched its 38 targets for “Health for All by the year 2000.”1 These stimulated European countries to reassess their health strategies and, in many cases, to set their own targets for health improvement. The WHO has recently revisited its earlier targets and created a new package with targets, “21 … for the 21st century.”2

This new policy will probably stimulate countries to reassess their health policies. But 15 years on, what are the lessons? Are health targets a useful component of health policy? What determines …
Hepatic-specific lipin-1 deficiency exacerbates experimental alcohol-induced steatohepatitis in mice
Authors: Ming Hu, Huquan Yin, Mayurranjan S. Mitra, Xiaomei Liang, Joanne M. Ajmo, Karim Nadra, Roman Chrast, Brian N. Finck, Min You
Journal: Hepatology (2013)

Lipin-1 regulates lipid metabolism by way of its function as an enzyme in the triglyceride synthesis pathway and as a transcriptional coregulatory protein and is highly up-regulated in alcoholic fatty liver disease. In the present study, using a liver-specific lipin-1-deficient (lipin-1LKO) mouse model, we aimed to investigate the functional role of lipin-1 in the development of alcoholic steatohepatitis and explore the underlying mechanisms. Alcoholic liver injury was achieved by pair feeding wild-type and lipin-1LKO mice with modified Lieber-DeCarli ethanol-containing low-fat diets for 4 weeks. Surprisingly, chronically ethanol-fed lipin-1LKO mice showed markedly greater hepatic triglyceride and cholesterol accumulation, and augmented elevation of serum liver enzymes accompanied by increased hepatic proinflammatory cytokine expression. Our studies further revealed that hepatic removal of lipin-1 in mice augmented ethanol-induced impairment of hepatic fatty acid oxidation and lipoprotein production, likely by way of deactivation of peroxisome proliferator-activated receptor γ coactivator-1alpha, a prominent transcriptional regulator of lipid metabolism. Conclusions: Liver-specific lipin-1 deficiency in mice exacerbates the development and progression of experimental alcohol-induced steatohepatitis. Pharmacological or nutritional modulation of hepatic lipin-1 may be beneficial for the prevention or treatment of human alcoholic fatty liver disease. (Hepatology 2013; 58:1953–1963)
Gross Pathology. A Color Atlas.
Authors: R.C. Curran, Edward Lynn Jones
Journal: Annals of Internal Medicine (1975)

Covering the range of structural disorders that underlie many diseases encountered in hospital practice, the 762 colour photographs in this atlas are mainly of unfixed tissues obtained in biopsy or at autopsy. The concise text serves to supplement the standard textbooks of pathology, and the greater information provided by colour pictures makes the atlas a natural response to the high visual content of pathology.
La matière vivante.
Authors: Félix Alexandre Le Dantec, Alfred Giard
Journal: JAMA (1925)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
REHABILITATION OF THE PATIENT WITH HEMIPLEGIA
Authors: D A COVALT
Journal: Annals of Internal Medicine (1952)

Article1 November 1952REHABILITATION OF THE PATIENT WITH HEMIPLEGIADONALD A. COVALT, M.D.DONALD A. COVALT, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-37-5-940 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptPatients with hemiplegia constitute one of the largest groups of persons suffering from chronic neurologic defects. It has been estimated that there are more than 1,000,000 at any one time in the United States.1As physicians, we have carefully treated the acute condition. If the patient survived, we have sent the patient home with little or no instruction as to his further care and rehabilitation. Some of these patients have been able to teach themselves to walk and have been able to resume a fairly normal life. At the Institute of Physical Medicine and Rehabilitation, we have found that many...Bibliography1. U. S. Public Health Service. The Magnitude of Chronic Disease Problems in the U. S.: The National Health Survey, 1935-1936, Washington, Government Printing Office, 1938. Google Scholar2. RuskMcCoy HAG Survey (to be published), . Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Presented at the Thirty-third Annual Session of the American College of Physicians, Cleveland, Ohio, April 25, 1952. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPotential reversibility of the hemiplegic postureRehabilitation in HemiplegiaTHE NATURAL HISTORY OF CEREBRAL THROMBOSIS*J. G. PINCOCK, M.D. 1 November 1952Volume 37, Issue 5Page: 940-943KeywordsRehabilitation medicine Issue Published: 1 November 1952 PDF downloadLoading ...
Transcatheter Arterial Chemoembolization Plus Radiotherapy Compared With Chemoembolization Alone for Hepatocellular Carcinoma
Authors: Ya Ruth Huo, Guy D. Eslick
Journal: JAMA Oncology (2015)

<h3>Importance</h3> Hepatocellular carcinoma (HCC) has the second-highest cancer-related mortality rate in the world because most patients are diagnosed at an intermediate to advanced stage when surgery is not suitable. Transcatheter arterial chemoembolization (TACE) is currently considered a first-line therapy for unresectable HCC. However, advancements in radiotherapy (RT) have resulted in some studies identifying a significant therapeutic benefit of TACE plus RT for unresectable HCC compared with TACE alone. <h3>Objective</h3> To evaluate the efficacy and safety of TACE plus RT compared with TACE alone for unresectable HCC using meta-analytical techniques. <h3>Data Sources</h3> A search of Medline, EMBASE, PubMed, Cochrane, and Google Scholar databases was done from inception to January 14, 2015. <h3>Study Selection</h3> Published trials that included a treatment group receiving TACE plus RT and a control group receiving TACE alone with data for at least 1-year survival or tumor response were included. <h3>Data Extraction and Synthesis</h3> Pooled odds ratios (ORs) and 95% CIs were calculated for the effect of TACE plus RT vs TACE alone on survival, tumor response, and adverse events using a random effects model. Subgroup analyses of study design, anticancer drug, RT type, embolization type, presence of portal venous tumor thrombosis (PVTT), and time between treatments with TACE and RT were performed. <h3>Main Outcomes and Measures</h3> Survival, tumor response, adverse events, study design, anticancer drug, RT type, embolization type, presence of PVTT, and time between TACE and RT. <h3>Results</h3> There were 25 trials (11 RCTs) involving 2577 patients. Patients receiving TACE plus RT showed significantly better 1-year survival (OR, 1.36 [95% CI, 1.19-1.54]) and complete response (clearance of the lesion after treatment) (OR, 2.73 [95% CI, 1.95-3.81]) compared with TACE alone. The survival benefit progressively increased for 2-, 3-, 4-, and 5-year survival (respectively: OR, 1.55 [95% CI, 1.31-1.85]; OR, 1.91 [95% CI, 1.55-2.35]; OR, 3.01 [95% CI, 1.38-6.55]; OR, 3.98 [95% CI, 1.86-8.51]). There was an increased incidence of gastroduodenal ulcers and elevated levels of alanine transaminase and total bilirubin in patients receiving TACE plus RT compared with those receiving TACE alone. Subgroup analyses showed nonsignificant trends in which survival was greater for TACE plus RT in patients with PVTT compared with those without PVTT. <h3>Conclusions and Relevance</h3> TACE plus RT was more therapeutically beneficial than TACE alone for treating HCC, and should be recommended for suitable patients with unresectable HCC.
Efficacy and Safety of Fondaparinux Versus Enoxaparin in Patients With Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention
Authors: Shamir R. Mehta, Christopher B. Granger, John W. Eikelboom, Jean-Pierre Bassand, Lars Wallentin, David P. Faxon, Ron J.G. Peters, Andrzej Budaj, Rizwan Afzal, Susan Chrolavicius, Keith A.A. Fox, Salim Yusuf
Journal: Journal of the American College of Cardiology (2007)
The Visitation With St Nicholas and St Anthony Abbot
Authors: M. Therese Southgate
Journal: JAMA (2002)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Factors affecting likelihood of applicants being offered a place in medical schools in the United Kingdom in 1996 and 1997: retrospective study Commentary: League tables will help Commentary: Some legal aspects arising from the study
Authors: I C McManus, A. Esmail, M. Demetriou
Journal: BMJ (1998)

<h3>Abstract</h3> <b>Objective</b> To assess the relation between a range of measures and the likelihood of applicants to medical schools in the United Kingdom being offered a place overall and at each medical school, with particular emphasis on ethnic minority applicants. <b>Design</b> Data provided by the Universities and Colleges Admissions Service on 92&nbsp;676 applications to medical schools from 18&nbsp;943 candidates for admission in 1996&nbsp;and 1997.&nbsp;Statistical analysis was by multiple logistic regression. <b>Main outcome measures</b> Receipt of a conditional or unconditional offer of a place at medical school. <b>Results</b> Eighteen separate measures were independently associated with the overall likelihood of receiving an offer. Applicants from ethnic minority groups were disadvantaged, as were male applicants, applicants applying late in the selection season, applicants making non-medical (so called insurance) choices, applicants requesting deferred entry (so called gap year), and applicants at further or higher education or sixth form colleges. Analysis at individual medical schools showed different patterns of measures that predicted offers. Not all schools disadvantaged applicants from ethnic minority groups and the effect was stable across the two years, suggesting structural differences in the process of selection. The degree of disadvantage did not relate to the proportion of applicants from ethnic minority groups. <b>Conclusions</b> The data released by the Council of Heads of Medical Schools allow a detailed analysis of the selection process at individual medical schools. The results suggest several areas in which some candidates are disadvantaged, in particular those from ethnic minority groups. Similar data in the future will allow monitoring of changes in selection processes.
Iatrogenic androgenetic alopecia in a male phenotype 46XX true hermaphrodite
Authors: S.H. Paik, H.H. Cho, H.C. Jeon, S.J. Jo, O.S. Kwon
Journal: British Journal of Dermatology (2011)

Journal Article Iatrogenic androgenetic alopecia in a male phenotype 46XX true hermaphrodite Get access S.H. Paik, S.H. Paik Department of Dermatology, Seoul National University College of Medicine, 101 Daehangno, Jongno‐gu, Seoul 110‐744, Korea Search for other works by this author on: Oxford Academic Google Scholar H.H. Cho, H.H. Cho Department of Dermatology, Seoul National University College of Medicine, 101 Daehangno, Jongno‐gu, Seoul 110‐744, Korea Search for other works by this author on: Oxford Academic Google Scholar H.C. Jeon, H.C. Jeon Department of Dermatology, Seoul National University College of Medicine, 101 Daehangno, Jongno‐gu, Seoul 110‐744, Korea Search for other works by this author on: Oxford Academic Google Scholar S.J. Jo, S.J. Jo Department of Dermatology, Seoul National University College of Medicine, 101 Daehangno, Jongno‐gu, Seoul 110‐744, Korea Search for other works by this author on: Oxford Academic Google Scholar O.S. Kwon O.S. Kwon Department of Dermatology, Seoul National University College of Medicine, 101 Daehangno, Jongno‐gu, Seoul 110‐744, Korea Oh Sang Kwon. E‐mail: oskwon@snu.ac.kr Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 166, Issue 1, 1 January 2012, Pages 221–222, https://doi.org/10.1111/j.1365-2133.2011.10511.x Published: 01 January 2012
HYPERCHLORHYDRIA, DUODENITIS AND DUODENAL ULCER: A CLINICAL STUDY OF THEIR INTERRELATIONSHIPS
Authors: J D OSTROW, R H RESNICK
Journal: Annals of Internal Medicine (1959)

ExcerptThe clinical features, roentgen appearance and therapeutic management of peptic ulceration of the duodenum represent familiar concepts in contemporary medical practice. The presence of a constant, barium-filled ulcer niche, with or without secondary roentgenologic signs, constitutes evidence for institution of a reasonably well defined program of extended care. On the other hand, alterations may occur in the mucosal pattern of the duodenum, not infrequently accompanied by hypermotility and/or hypersecretion,in the absence of frank ulceration, a radiologic appearance usually referred to as duodenitis. Other patients, with complaints simulating peptic ulcer, have a completely normal upper gastrointestinal series but demonstrate gastric...
Abstract 321: Synergistic Effect of Coronary Artery Disease Risk Factors on Long-term Survival in Patients Without Cardiac Disease and a Normal Treadmill Stress SPECT
Authors: Seth Uretsky, Padmakshi Singh, Azhar Supariwala, Prashanth Atluri, Surinder S Khokhar, Hari K Koppuravuri, Rajeev Joshi, Alan Rozanski
Journal: Circulation (2009)