THE RÔLE OF GONADAL AND ADRENAL CORTICAL HORMONES IN THE PRODUCTION OF EDEMA
Authors: George W. Thorn, Kendall Emerson
Journal: Annals of Internal Medicine (1940)

Article1 November 1940THE RÔLE OF GONADAL AND ADRENAL CORTICAL HORMONES IN THE PRODUCTION OF EDEMAGEORGE W. THORN, F.A.C.P., KENDALL EMERSON JR.GEORGE W. THORN, F.A.C.P., KENDALL EMERSON JR.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-14-5-757 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptFEMALE SEX HORMONESThe occurrence of generalized edema, associated with menstruation has been reported by Thomas,1 Sweeney,2 Molnar and Gruber3 and Atkinson and Ivy.4 Experimentally it has been observed5 that the intramuscular injection of large doses of crystalline sex hormones (estrone, estradiol, testosterone and progesterone) in both male and female dogs resulted in a striking, but temporary, retention of sodium, chloride and water. Qualitative as well as quantitative differences were also noted in the effect of treatment with sex hormones on the renal excretion of potassium, phosphate and nitrogen.5In a recent study6it was noted that 24 of a...Bibliography1. THOMAS WA: Generalized edema occurring only at menstrual period, Jr. Am. Med. Assoc., 1933, ci, 1126. CrossrefGoogle Scholar2. SWEENEY JS: Menstrual edema; preliminary report, Jr. Am. Med. Assoc., 1934, ciii, 234. CrossrefGoogle Scholar3. MOLNARGRUBER SZ: Mit der Menstruation Zusammenhängendes Ödem unklarer Genese, Klin. Wchnschr., 1934, xiii, 369. CrossrefGoogle Scholar4. ATKINSONIVY AJAC: Menstrual edema; report of case controlled by emmenin but not by theelol or theelin, Jr. Am. Med. Assoc., 1936, cvi, 515. CrossrefGoogle Scholar5. THORNENGEL GWLL: Effect of sex hormones on renal excretion of electrolytes, Jr. Exper. Med., 1938, lxviii, 299. CrossrefGoogle Scholar6. 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THORNHOWARDEMERSON GWRPK: Treatment of Addison's disease with desoxy-corticosterone acetate, synthetic adrenal cortical hormone (preliminary report), Jr. Clin. Invest., 1939, xviii, 449. CrossrefGoogle Scholar18. FERREBEERAGANATCHLEYLOEB JWCDWRF: Desoxycorticosterone esters; certain effects in treatment of Addison's disease, Jr. Am. Med. Assoc., 1939, cxiii, 1725. Google Scholar19. ANDERSONHAYMAKERJOSEPH EWM: Hormone and electrolyte studies of patients with hyperadrenocortical syndrome (Cushing's syndrome), Endocrinology, 1938, xxiii, 398. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: GEORGE W. THORN, F.A.C.P.; KENDALL EMERSONJR.Affiliations: New York, N. Y.*Read at the Cleveland Meeting of the American College of Physicians, April 3, 1940.From the Chemical Division, Medical Clinic, The Johns Hopkins University and Hospital, Baltimore, Maryland.†Aided, in part, by a grant from the Committee on Research in Endocrinology, National Research Council. Nextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byRENAL EXCRETION OF WATER AND SOLUTES DURING THE NORMAL MENSTRUAL CYCLEThe Effects of Gonadal Hormones on Water and Electrolyte Metabolism in the HumanSonstige Wirkungen von GestagenenThe Relation of Urine Volume to the Menstrual Cycle and OvulationThe use of Na22 to study the sodium-retaining properties of steroid therapy in rheumatoid arthritisNewer DiureticsPathophysiologie der HerzinsuffizienzDiuretic therapy in syndromes associated with sodium and water retention∗Menstruation and Systemic DiseaseSome reflections on mechanisms of action of diureticsToxemia of pregnancy: A new treatment for controlling edemaThe endocrine basis for the body weight changes and the metabolism of water in the adult female baboon (Papio ursinus)Die Zirkulationsstörungen der LungeNachweis von Mineralocorticoidhormon in der Leber von Kaninchen mit normalen und hypertrophischen NebennierenSOME OBSERVATIONS ON THE RELATIONSHIP BETWEEN WEIGHT CHANGES FOLLOWING SODIUM RESTRICTION AND THOSE ASSOCIATED WITH THE MENSTRUAL CYCLE IN NORMAL YOUNG WOMEN*CAROLINE BEDELL THOMAS, M.D., F.A.C.P.ELECTROLYTES AND CONGESTIVE FAILURE*T. S. DANOWSKI, F.A.C.P.Serum Electrolytes in the Menstrual CycleElectrolyte and Water Metabolism: Physiologic ConsiderationsElectrolyte and Fluid Disturbances in Congestive Heart FailureCyclic Premenstrual Congestive Heart FailureNewer concepts of the role of sodium in diseaseThe Effect of Salt Loading and Salt Depletion on Renal Function and Electrolyte Excretion in ManKlinisch experimentelle Untersuchungen zur Frage der pr�menstruellen Beschwerden und funktionellen DysmenorrhoeFree-feeding pregnant womenSodium loss in man induced by desoxycorticosterone acetateTreatment of Renal InsufficiencyPathogenesis of peripheral cardiac edemaMenstrual ToxinPremenstrual EdemaThe psychosomatic aspect of dysmenorrheaClinical Management of Edema in Bright's DiseaseWeight Changes and Water Balance in Normal and Toxic PregnancyCardiovascular effects of desoxycorticosterone acetate in man 1 November 1940Volume 14, Issue 5 Page: 757-769 Keywords Excretion Hormones Hospitals Intramuscular injections Phosphates Potassium Progesterone Sex hormones Sodium chloride Testosterone ePublished: 1 December 2008 Issue Published: 1 November 1940 Copyright & PermissionsCopyright, 1940, by The American College of PhysiciansPDF downloadLoading ...