ACUTE PORPHYRIA: A CASE REPORT
Authors: G W MELLINGER, C C PEARSON
Journal: Annals of Internal Medicine (1953)

Case Reports1 April 1953ACUTE PORPHYRIA: A CASE REPORTGEORGE W. MELLINGER, M.D., CLARENCE C. PEARSON, M.D., F.A.C.P.GEORGE W. MELLINGER, M.D.Search for more papers by this author, CLARENCE C. PEARSON, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-38-4-862 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAcute porphyria is an inborn or acquired error of metabolism characterized by the urinary excretion of abnormal quantities of uroporphyrin, coproporphyrin and porphobilinogen, and manifested clinically by intermittent attacks of acute abdominal pain, constipation, neurologic symptoms or psychic disturbances. The varied clinical features, as well as the pathologic chemistry of the condition, have been adequately reviewed,1, 2, 3, 4, 5and the present authors can add nothing to these excellent presentations. One point deserves emphasis, however. Acute porphyria may present such varied symptoms that the diagnosis is often not considered for several years after the onset.6The test for urinary...Bibliography1. WatsonLarson CJEA: The porphyrins and their relation to disease: Porphyria; Oxford Medicine 46: 228 (1), 1951. Google Scholar2. DobrinerRhoads KCP: The porphyrins in health and disease, Physiol. Rev. 20: 416, 1940. CrossrefGoogle Scholar3. Nesbitt S: Acute porphyria, J. A. M. A. 124: 286, 1944. CrossrefGoogle Scholar4. Denny-BrownSciarra DD: Changes in the nervous system in acute porphyria, Brain 68: 1, 1945. CrossrefGoogle Scholar5. Watson CJ: Some recent studies of porphyrin metabolism and porphyria, Lancet 1: 539, 1951. CrossrefMedlineGoogle Scholar6. Peters GA: Acute porphyria. Report of two cases with electrical studies in one, Ann. Int. Med. 30: 1237, 1949. LinkGoogle Scholar7. WatsonSchwartz CJS: A simple test for urinary porphobilinogen, Proc. Soc. Exper. 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PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAktinische DermatosenDas adrenocorticotrope Hormon (ACTH), die HormonederNebenniere(Cortison,Adrenalin) das Insulin, sowie die Hormone der Schilddrüse und NebenschilddrüseAcute intermittent porphyriaBARBITURATE NARCOSIS IN PORPHYRIACORTISONE THERAPY IN PORPHYRIA HEPATICA, ACUTE INTERMITTENT TYPE: A REPORT OF UNFAVORABLE RESULTS*O. CHARLES OLSON, M.D., F.A.C.P., MERRITT H. STILES, M.D., F.A.C.P. 1 April 1953Volume 38, Issue 4Page: 862-868KeywordsAbdominal painConstipationExcretionHospital medicineInborn errors of metabolismMedical servicesPorphyria ePublished: 1 December 2008 Issue Published: 1 April 1953 PDF downloadLoading ...