WATERHOUSE-FRIDERICHSEN SYNDROME IN VARICELLA
Authors: R R MONTGOMERY, M OLAFSSON
Journal: Annals of Internal Medicine (1960)

Case Reports1 September 1960WATERHOUSE-FRIDERICHSEN SYNDROME IN VARICELLAROBERT R. MONTGOMERY, M.D., MAGNUS OLAFSSON, M.D.ROBERT R. MONTGOMERY, M.D., MAGNUS OLAFSSON, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-53-3-576 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe Waterhouse-Friderichsen syndrome typically appears early in the course of severe meningococcic infection, and usually leads swiftly to death. It is characterized by shock, prostration, purpura, and massive hemorrhage into the adrenal glands. Until the advent of sulfonamides, antibiotics and, later, adrenal corticosteroids, it was usually fatal; indeed, if a patient survived, the accuracy of the diagnosis was questioned.Since its initial description and later clinical definition, it had been reported as occurring in the course of various other infectious diseases. As far as we can determine after an extensive review of the literature, the following case is the first...Bibliography1. FitzMeiklejohn RHG: Varicella pneumonia in adults, Am. J. M. Sc. 232: 489-499, 1956. CrossrefMedlineGoogle Scholar2. Claudy WD: Pneumonia associated with varicella, Arch. Int. Med. 80: 185-192, 1947. CrossrefGoogle Scholar3. Eisenbud M: Chickenpox with visceral involvement, Am. J. Med. 12: 740-746, 1952. CrossrefMedlineGoogle Scholar4. RosencanBaumgartenCharles MWBH: Varicella pneumonia with shock and heart failure, Ann. Int. Med. 38: 830-845, 1953. LinkGoogle Scholar5. Glanzman E: Beitrag zur Klinik Hämatologie und Pathologie des Syndroms von Waterhouse-Friderichsen, Jahrb. f. Kinderh. 139: 49-63, 1933. Google Scholar6. Pronove-Irreverre P: Waterhouse-Friderichsen syndrome. A review of the literature and a report of two cases of fulminating meningococcic septicemia, Clin. Proc. Child. Hosp. 10: 41-54, 1954. MedlineGoogle Scholar7. Daniels WB: Cause of death in meningococcic infection, Am. J. Med. 8: 468-473, 1950. CrossrefMedlineGoogle Scholar8. KanterMaurielloLearner DMDAN: Acute meningococcemia with vascular collapse: an analysis of 10 recently treated cases, Am. J. M. Sc. 232: 674-687, 1956. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication March 13, 1959.Requests for reprints should be addressed to Robert R. Montgomery, M.D., 1746 K Street, Northwest, Washington, D. C. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byHistopathological Analysis of Adrenal Glands after Simian Varicella Virus InfectionBilateral massive adrenal hemorrhageHerpes- und verwandte VirenDisseminated intravascular coagulation and the Waterhouse-Friderichsen syndromeVaricella Pneumonia in Pregnancy with Varicella Neonatorum: Report of a Case followed by Severe Digital ClubbingGeneralisierte plasmatische Hypercoagulabilit�t und pulmonale hyaline Membranen beim ErwachsenenVaricella pneumonia in pregnancyFATAL VARICELLA IN AN ADULTDie kindlichen Nebennieren und ihre PathologieCase 47-1962Varicella PneumoniaRICHARD H. MERMELSTEIN, M.D., ABRAHAM W. FREIREICH, M.D., F.A.C.P. 1 September 1960Volume 53, Issue 3Page: 576-579KeywordsAdrenal glandsAntibioticsHemorrhageInfectious diseasesMeningococcal diseaseNorepinephrinePneumoniaShockSulfonamide ePublished: 1 December 2008 Issue Published: 1 September 1960 PDF downloadLoading ...