AN EVALUATION OF RADICAL SURGERY FOR CARCINOMA OF THE PANCREAS AND AMPULLARY REGION
Authors: A O WHIPPLE
Journal: Annals of Internal Medicine (1949)

Article1 October 1949AN EVALUATION OF RADICAL SURGERY FOR CARCINOMA OF THE PANCREAS AND AMPULLARY REGIONALLEN O. WHIPPLE, M.D.ALLEN O. WHIPPLE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-31-4-624 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe justification for present day radical surgery should be determined by the threat of the untreated lesion, the operative risk if radically treated, the life expectancy after operation, and the prospect of comfortable living subsequently. Radical surgery may be curative, but much of it may be only palliative. This of course is true of many forms of medical therapy.Radical surgery of the past 15 years, and especially that of today, has been made possible by many factors: a better understanding of supportive treatment, blood transfusion, maintenance of fluid, protein and electrolyte balance, improved methods of anesthesia, intelligent use of...Bibliography1. KAUSCH W: Das Carcinom der Papilla duodeni und seine radikale Entfernung, Beitr. klin. Chir., 1912, lxxviii, 439-486. HIRSCHEL, G.: Die Resektion der Duodenums mit der Papille wegen Karzinoms, München. med. Wchnschr., 1914, lxi, 1728. TENANI, O.: Contributo alla chirurgia della papilla del Vater, Policlinico, 1922, xxix, 291. Google Scholar2. HOWLANDCAMPBELLMALTBYROBINSON GWREJWL: Dysinsulinism; convulsions and coma due to islet cell tumor of pancreas, with operation and cure, Jr. Am. Med. Assoc., 1929, xciii, 674-679. CrossrefGoogle Scholar3. WHIPPLEPARSONSMULLINS AOWBCR: Treatment of carcinoma of the ampulla of Vater, Ann. Surg., 1935, cii, 763. CrossrefGoogle Scholar4. WHIPPLE AO: Pancreatoduodenectomy for islet cell carcinoma: a five year followup, Ann. Surg., 1945, cxxi, 847. CrossrefGoogle Scholar5. PRIESTLEYCOMFORTRADCLIFFE JTMWJ: Total pancreatectomy for hyperinsulinism, Ann. Surg., 1944, cxix, 211. CrossrefGoogle Scholar6. PAVLOV JP: Die Arbeit der Verdauungsdrüsen, 1898, Wiesbaden. Google Scholar7. BAYLISSSTARLING WMEH: The mechanism of pancreatic secretion, Jr. Physiol., 1902, xxviii, 325. CrossrefGoogle Scholar8. LAGERLÖF HO: Pancreatic function and pancreatic disease studied by means of secretin, 1942, P. A. Norstedt and Söner, Stockholm. Google Scholar9. COMFORTPARKEROSTERBURG MWRLAE: Concentration of pancreatic enzymes in the duodenum of normal persons and persons with disease of the upper abdomen, Am. Jr. Digest. Dis., 1939, vi, 249. CrossrefGoogle Scholar10. BAUMANWHIPPLE LAO: The diagnostic value of pancreatic function tests in 47 surgically treated patients, Am. Jr. Med. Sci., 1944, ccvii, 281. CrossrefGoogle Scholar11. CATTELLPYRTEK RBLJ: An appraisal of pancreatoduodenectomy: a followup study of 61 cases. Read before the Southern Surgical Association Meeting, Dec. 6, 1948; to be published in Ann. Surg., 1949. Also personal communication, March 8, 1949. Google Scholar12. LOCKWOOD JS: Personal communication, March 28, 1949. Google Scholar13. WAUGH JM: Personal communication, March 15, 1949. Google Scholar14. BRUNSCHWIG A: Personal communication, March 20, 1949. Google Scholar15. HOWES EL: Experiments not yet published. Quoted by Dr. Lockwood. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Read before the Thirtieth Annual Session of the American College of Physicians, New York, N. Y., March 31, 1949. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byGemcitabine-based neoadjuvant chemotherapy for locally advanced pancreatic cancer does not affect mortality and morbidity after pancreatic resectionNeoGemTax: Gemcitabine and Docetaxel as Neoadjuvant Treatment for Locally Advanced Nonmetastasized Pancreatic CancerDuodenopancreatectomía cefálica en tumores periampulares. Disección de la arteria mesentérica superior como abordaje inicial. Descripción de la técnica y evaluación de nuestra experiencia inicialControversies in the Surgical Management of Pancreatic CancerClinicopathologic Features and Treatment Trends of Pancreatic Neuroendocrine Tumors: Analysis of 9,821 PatientsNational Failure to Operate on Early Stage Pancreatic CancerSurgery for Pancreatic Cancer: Recent Controversies and Current PracticeA review of important contributions of surgery for cancer of the gastrointestinal tractCarcinoma of the pancreasCancer of the pancreasDie Krankheiten der BauchspeicheldrüseCancer of the Pancreas.: A Clinical mid Pathological Studya,b,c,d 1 October 1949Volume 31, Issue 4Page: 624-627KeywordsAnesthesiaBlood transfusionLesionsLife expectancyPalliative carePancreasProteinsSurgery ePublished: 1 December 2008 Issue Published: 1 October 1949 PDF downloadLoading ...