BLOOD DYSCRASIAS SECONDARY TO GOLD: WITH A CASE OF HYPOPLASTIC ANEMIA CURED BY SPLENECTOMY
Authors: H J L MARRIOTT, H R PETERS
Journal: Annals of Internal Medicine (1950)

Article1 May 1950BLOOD DYSCRASIAS SECONDARY TO GOLD: WITH A CASE OF HYPOPLASTIC ANEMIA CURED BY SPLENECTOMYHENRY J. L. MARRIOTT, B.M. (Oxon.), H. RAYMOND PETERS, M.D., F.A.C.P.HENRY J. L. MARRIOTT, B.M. (Oxon.)Search for more papers by this author, H. RAYMOND PETERS, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-32-5-864 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptHematologic reactions are among the rarer, but more serious results of chrysotherapy; of these thrombocytopenia is by far the commonest. Granulocytopenia and aplastic anemia have been reported less frequently. Of the three dyscrasias aplastic anemia has proved most fatal.Thrombocytopenia. More cases of hemorrhagic purpura than of any other blood disorder have been recorded following gold administration. It is remarkable that in many reports platelet counts are not given, and so thrombocytopenia, in some cases, can only be assumed.Emile-Weil1reported one case of hemorrhagic purpura in 1931; he and Bousser2later referred to 30 instances of "hemorrhagic accidents," but...Bibliography1. Weil PE: Le grand purpura hémorragique d'origine aurique, Paris méd. 81: 102, 1931. Google Scholar2. WeilBousser PEJ: Les états hémorragiques post-auriques, Le Sang 6: 825, 1932. Google Scholar3. WintrobeStowellRoll MMARM: Report of a case of aplastic anemia following gold injections in which recovery occurred, Am. J. M. Sci. 197: 698, 1939. CrossrefGoogle Scholar4. HartfallGarland SJHG: Gold treatment of rheumatoid arthritis, Lancet 2: 8, 1935. CrossrefGoogle Scholar5. HartfallGarland SJHG: Further observations on gold treatment of rheumatoid arthritis, ibid. 1: 1459, 1936. Google Scholar6. HartfallGarlandGoldie SJHGW: Gold treatment of arthritis: review of 900 cases, ibid. 2: 838, 1937. Google Scholar7. 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Author, Article, and Disclosure InformationAffiliations: Baltimore, Maryland*Received for publication March 22, 1949.From the Department of Medicine, Mercy Hospital, University of Maryland, School of Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byHospitalizations for Aplastic Anemia and Agranulocytosis in SaskatchewanThe history of gold therapy in rheumatoid diseaseDie Panmyelopathie und andere Formen der PancytopenieTierexperimentelle Untersuchungen zur medikamentös-allergischen Agranulocytose SchultzReticulocyte Count in Patients with Rheumatoid Arthritis, with Observations on the Effect of Gold Therapy on Bone Marrow FunctionDie Pathologie des Stoffwechsels der SchwermetalleSplenectomy in blood disordersDRUG INDUCED HYPOPLASTIC ANEMIAS AND RELATED SYNDROMES*EDWIN E. OSGOOD, M.D., F.A.C.P.GOLD THERAPY FOR RHEUMATOID ARTHRITIS: A CURRENT EVALUATION*W. GRAFTON HERSPERGER, M.D., F.A.C.P. 1 May 1950Volume 32, Issue 5Page: 864-877KeywordsAplastic anemiaBloodHospital medicinePlateletsSplenectomy ePublished: 1 December 2008 Issue Published: 1 May 1950 PDF downloadLoading ...