THIOCYANATE GOITER IN MAN
Authors: Rulon W. Rawson, S. Hertz, J. H. Means
Journal: Annals of Internal Medicine (1943)

Article1 December 1943THIOCYANATE GOITER IN MANRULON W. RAWSON, S. HERTZ, J. H. MEANS, F.A.C.P.RULON W. RAWSONSearch for more papers by this author, S. HERTZSearch for more papers by this author, J. H. MEANS, F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-19-6-829 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThat a definite relationship exists between iodine deficiency and many non-toxic goiters is well established. Indeed endemic goiter is usually, and perhaps too readily, accepted as being due to iodine deficiency. Experimentally, thyroid hyperplasia has been produced in various laboratory animals by many goitrogenic agents other than iodine deficient diets. Astwood, et al.1 in a recent report, referred to extensive literature on a variety of goitrogens.Some of the most interesting studies in goitrogenesis were incited by observations made by Chesney, Clawson and Webster2, 3, 4in 1928. They observed large hyperplastic goiters in rabbits maintained on cabbage diets. In...Bibliography1. ASTWOODSULLIVANBISSELLTYSLOWITZ EBJAR: Action of certain sulfonamides and of thiourea upon the function of the thyroid gland of the rat, Endocrinology, 1943, xxxii, 210. CrossrefGoogle Scholar2. CHESNEYCLAWSONWEBSTER AMTAB: Endemic goitre in rabbits. I. Incidence and characteristics, Bull. Johns Hopkins Hosp., 1928, xliii, 261. Google Scholar3. WEBSTERCLAWSONCHESNEY BTAAM: Endemic goitre in rabbits. II. Heat production in goitrous and non-goitrous animals, Bull. Johns Hopkins Hosp., 1928, xliii, 278. Google Scholar4. WEBSTERCHESNEY RAM: Endemic goitre in rabbits. III. Effect of administration of iodine, Bull. Johns Hopkins Hosp., 1928, xliii, 291. 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RAWSONGRAHAMRIDDELL RWRMCB: Physiological reactions of the thyroid-stimulating hormone of the pituitary. II. The effect of normal and pathological human thyroid tissues on the activity of the thyroid stimulating hormone, ANN. INT. MED., 1943, xix, 405-414. Google Scholar24. MARINEROSENCIPRA DSHA: Further studies on the exophthalmos in rabbits produced by methyl cyanide, Proc. Soc. Exper. Biol. and Med., 1933, xxx, 649. CrossrefGoogle Scholar25. WILLIAMSBISSELL RHGW: Thiouracil in the treatment of thyrotoxicosis, New England Jr. Med., 1943, ccxxix, 97. CrossrefGoogle Scholar26. LERMAN J: Personal communication. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Boston, Massachusetts*Received for publication May 19, 1943.From the Thyroid Clinic of the Massachusetts General Hospital. Aided in part by grants from the John and Mary R. Markle Foundation, the H. N. C. Gift and Proctor Fund, Harvard University. Read in preliminary form at the meeting of the American Society for Clinical Investigation in Atlantic City, May 4, 1942.†Research Fellow of the American College of Physicians, 1941-42. Henry P. Walcott Fellow, Harvard University, 1942-43. Nextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byA Comparative Toxicological Assessment of Perchlorate and Thiocyanate Based on Competitive Inhibition of Iodide Uptake as the Common Mode of ActionIodide transport in the thyroid glandChronische cyanidvergiftungThyroid cancer and thyrotoxicosis in the United States: Their relation to endemic goiterREFERENCESChemistry and Physiology of the Thyroid-stimulating HormoneDie Diagnostik der Schilddrüsen-Erkrankungen mit radioaktivem JodKrankheiten der SchilddrüseObservations on thyroid function in hypertensive patients treated with potassium thiocyanateDetermination of thiocyanate in body fluidsMethoden und Ergebnisse des Radiojodstoffwechselstudiums zur Diagnostik thyreoidaler und extrathyreoidaler ErkrankungenDiseases of the Thyroid GlandThe Cause of Simple GoitreOn the influence of anti-thyroid substances on the hormone production of the thyroid glandBiochemie der Schilddr�seJodstoffwechsel, Schilddr�se und HypophysenvorderlappenThiocyanate Effect Following Industrial Cyanide ExposureACTIVITY OF SOME FURTHER SYNTHETIC ŒSTROGENS DETERMINED BY EXPERIMENTS ON RATSMYXŒDEMA FROM RESORCINOL OINTMENT APPLIED TO LEG ULCERSBeeinflussung spezieller Organe und Organsysteme durch AnionenThe Control of Thyroid ActivityBibliographyThe Mode of Action and Clinical Uses of the Thiouracil Group of DrugsEtiology of goiter in manRadioactive Iodine: Its use in Studying the Urinary Excretion of Iodine by Humans in Various States of Thyroid Function.Some Recent Advances in Study of the Thyroid: Their Influence on the Treatment of Thyroid DiseasesTHE CONVERSION OF THIOCYANATE SULFUR TO SULFATE IN THE WHITE RATTHIOURACIL AND THYROTOXICOSISThe Biology of Antithyroid AgentsHypothyroidism and mild myxedema from thiocyanate intoxicationCretinismToxic, Allergic and «Myxedematoid» Symptoms in the Treatment of Thyrotoxicosis with Antithyroid Substances (Thiourea, Thiouracil, Methylthiouracil)Thiouracil Therapy in the Preoperative Preparation of Thyrotoxic PatientsThiouracilThiouracil in hyperthyroidism**Formerly, Director of Technical Service, Pharmaceutical Dept., Calco Chemical Division.Thiouracil and Hyperthyroidism 1 December 1943Volume 19, Issue 6Page: 829-842KeywordsDietHospitalsRabbitsResearch laboratoriesThyroid ePublished: 1 December 2008 Issue Published: 1 December 1943 Copyright & PermissionsCopyright, 1943, by The American College of PhysiciansPDF downloadLoading ...