THERAPY OF ACUTE BARBITURATE POISONING: REPORT OF THREE CASES
Authors: M ROCHE, L C WYNNE, D M HASKINS
Journal: Annals of Internal Medicine (1950)

Article1 July 1950THERAPY OF ACUTE BARBITURATE POISONING: REPORT OF THREE CASESMARCEL ROCHE, M.D., LYMAN C. WYNNE, M.D., DONALD M. HASKINS, M.D.MARCEL ROCHE, M.D.Search for more papers by this author, LYMAN C. WYNNE, M.D.Search for more papers by this author, DONALD M. HASKINS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-33-1-73 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe following cases are believed to be of interest because: (1) They illustrate recovery from barbiturate intoxication, potentially fatal in degree, without the use of picrotoxin. (2) Correlation between the clinical status and blood barbiturate levels was made.†CASE REPORTSCase 1. (Figure 1.) This 40 year old taxi driver was perfectly well the evening before admission. At 8 a.m. on the day of admission, the patient's wife noticed that her husband was "asleep and breathing very heavily." At noon, the first attempt at awakening was made, without success. The local physician was called; he administered adrenalin and caffeine with...Bibliography1. WalkerFisherMcHugh JTRSJJ: Quantitative estimation of barbiturates in blood by ultraviolet spectrophotometry. I. Analytical method, Am. J. Clin. Path. 18: 451-461, 1948. CrossrefMedlineGoogle Scholar2. FisherWalkerPlummer RSJTCW: Quantitative estimation of barbiturates in blood by ultraviolet spectrophotometry, Am. J. Clin. Path. 18: 462-469, 1948. CrossrefMedlineGoogle Scholar3. Hambourger WE: Promiscuous use of barbiturates; analysis of hospital data, J. A. M. A. 114: 2015-2019, 1940. Google Scholar4. GoodmanGilman LA: The pharmacological basis of therapeutics, 1941, The Macmillan Company, New York. Google Scholar5. Sollmann T: A manual of pharmacology, 1937, Saunders, New York. Google Scholar6. 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Fisher, Department of Legal Medicine, Harvard Medical School, for his generous coöperation in performing the barbiturate determinations in these cases and for allowing the use of his data in this report. These determinations were made with a new rapid and accurate spectrophotometric technic.1, 2 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byBarbituratesAcute Pulmonary Edema Caused by Barbiturate PoisoningDie Therapie der SchlafmittelvergiftungenAn appraisal of the present treatment of barbiturateThe treatment of barbiturate poisoning with or without analepticsACUTE BARBITURATE INTOXICATION: A STUDY OF 300 CASES BASED ON A PHYSIOLOGIC SYSTEM OF CLASSIFICATION OF THE SEVERITY OF THE INTOXICATION*CHARLES E. REED, M.D., MARSHALL F. DRIGGS, M.D., F.A.C.P., CHARLES C. FOOTE, M.D. 1 July 1950Volume 33, Issue 1Page: 73-82KeywordsBloodBreathingCaffeineHospital medicineIntoxicationResearch design ePublished: 1 December 2008 Issue Published: 1 July 1950 PDF downloadLoading ...