RENAL DISEASE WITH THE SALT LOSING SYNDROME: A REPORT OF FOUR CASES OF SO-CALLED "SALT LOSING NEPHRITIS"
Authors: F D MURPHY, A L SETTIMI, N J KOZOKOFF
Journal: Annals of Internal Medicine (1953)

Article1 June 1953RENAL DISEASE WITH THE SALT LOSING SYNDROME: A REPORT OF FOUR CASES OF SO-CALLED "SALT LOSING NEPHRITIS"FRANCIS D. MURPHY, M.D., F.A.C.P., ALBINO L. SETTIMI, M.D., NORMAN J. KOZOKOFF, M.D.FRANCIS D. MURPHY, M.D., F.A.C.P.Search for more papers by this author, ALBINO L. SETTIMI, M.D.Search for more papers by this author, NORMAN J. KOZOKOFF, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-38-6-1160 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptChronic renal insufficiency produced by any progressive disease of the kidney may be associated with a variety of complications. Traditionally, it is known that diseased kidneys fail to excrete nitrogenous substances, and that this retention leads to azotemia and uremia. While the retention of salt and water by the kidney is considered the main cause of edema, any progressive kidney disease, whether polycystic kidney, chronic glomerulonephritis, tuberculosis of the kidney or pyelonephritis, may become associated not only with retention but also with excessive depletion of certain essential substances.For some years the significance of abnormally low serum electrolytes has been...Bibliography1. Murphy FD: Acute toxic nephrosis, Postgrad. Med. 12: 191-200 (Sept.) 1952. CrossrefMedlineGoogle Scholar2. HunterMuirhead RBEE: Prolonged renal salt wastage in lower nephron nephrosis, Ann. Int. Med. 36: 1297-1308 (May) 1952. LinkGoogle Scholar3. PetersWakemanEisenmanLee JPAMAJC: Total acid-base equilibrium of plasma in health and disease. X. The acidosis of nephritis, J. Clin. Investigation 6: 517-549 (Feb.) 1929. CrossrefMedlineGoogle Scholar4. PetersWakemanLee JPAMC: Total acid-base equilibrium of plasma in health and disease. XI. Hypochloremia and total salt deficiency in nephritis, J. Clin. Investigation 6: 551-596 (Feb.) 1929. CrossrefMedlineGoogle Scholar5. PetersVan Slyke JPDD: Quantitative clinical chemistry, Vol. I. Interpretations, 1931, Williams & Wilkins Company, Baltimore. Google Scholar6. LandisElsomBottShiels EMKAPAE: Observations on sodium chloride restriction and urea clearance in renal insufficiency, J. Clin. Investigation 14: 525-541 (Sept.) 1935. CrossrefMedlineGoogle Scholar7. ThornKoepfClinton GWGFM: Renal failure simulating adrenocortical insufficiency, New England J. Med. 231: 76-85 (July 20) 1944. CrossrefGoogle Scholar8. SawyerSolez WHC: Salt-losing nephritis simulating adrenocortical insufficiency: report of a case, New England J. Med. 240: 210-215 (Feb. 10) 1949. CrossrefMedlineGoogle Scholar9. NussbaumBernhardMattia HEWGVD: Chronic pyelonephritis simulating adrenal cortical insufficiency, New England J. Med. 246: 289-293 (Feb. 21) 1952. CrossrefMedlineGoogle Scholar10. Borst JR: Disturbances in water and salt metabolism in the final stage of chronic renal insufficiency, Acta med. Scandinav. 136: 1-8, Fasc. 1, 1949. CrossrefMedlineGoogle Scholar11. JoinerThorne CLMG: Salt-losing nephritis, Lancet 2: 454-458 (Sept. 6) 1952. CrossrefMedlineGoogle Scholar12. Enticknap JB: The condition of the kidneys in salt losing nephritis, Lancet 2: 458-461 (Sept. 6) 1952. CrossrefMedlineGoogle Scholar13. BlackLitchfield ABJA: Uremia complicating low salt treatment of heart failure, Quart. J. Med. 20: 149-162 (April) 1951. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Milwaukee, Wisconsin*Received for publication November 25, 1952.From the Department of Medicine, Marquette University School of Medicine and Milwaukee County Hospital.Presented at the Midwest Regional Meeting of the American College of Physicians, Chicago, Illinois, November 22, 1952. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySerologic and urinary characteristics of laboratory-confirmed genitourinary tuberculosis at a tertiary hospital in the PhilippinesObstructive sodium-losing nephropathy--a case report and review.Fanconi syndrome with renal sodium wasting and metabolic alkalosisUropoietic SystemDisorders of renal functionThe kidney in health; the nephron in diseaseHypophosphatemic rickets due to glomerular and tubular renal insufficiencyFunktionelle Orthologie und Pathologie der NierenausscheidungDie Pathomorphologie der NierenausscheidungDie tubulären NierensyndromeSalt-Losing NephritisSYNDROME OF MASKED HYPERPARATHYROIDISM*DONALD H. ATLAS, M.D., Ph.D., F.A.C.P., PETER GABERMAN, M.D., HERMAN L. EISENBERG, M.D.Salt Losing Syndrome in Nephropathy (Cases of salt losing nephritis, one with extensive soft tissue calcification)The Modern Conception of Bright's DiseaseErnährungstherapieErnährungstherapie 1 June 1953Volume 38, Issue 6Page: 1160-1176KeywordsChronic kidney diseaseEdemaGlomerulonephritisHospital medicineNephritisPolycystic kidney diseaseProgressive diseasesPyelonephritisRenal diseasesSalts ePublished: 1 December 2008 Issue Published: 1 June 1953 PDF downloadLoading ...