SOME BASIC, UNSOLVED PROBLEMS IN THE PREVENTION OF RHEUMATIC FEVER
Authors: A F COBURN
Journal: Annals of Internal Medicine (1957)

Article1 September 1957SOME BASIC, UNSOLVED PROBLEMS IN THE PREVENTION OF RHEUMATIC FEVERALVIN F. COBURN, M.D.ALVIN F. COBURN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-47-3-402 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptPhysicians concerned with problems in the prevention of rheumatic fever have for more than half a century been confronted with two facts in the epidemiology of this disease. Wherever investigated, it has been observed that (a) outbreaks of rheumatic fever occurred following epidemics of "sore throats" or scarlatina, and (b) onset of the rheumatic state was confined almost exclusively to low income families. The first of these facts has been the subject of widespread research for more than a quarter of a century; the second has not yet received the attention that it deserves. Today I wish to deal briefly...Bibliography1. AndrewesGlover CHRE: Spread of infection from respiratory tract of ferret; transmission of influenza A virus, Brit. J. Exper. Path. 22: 91-97 (Apr.) 1941. Google Scholar2. Glover RE: Spread of infection from respiratory tract of ferret; association of influenza A virus and streptococcus group C, Brit. J. Exper. Path. 22: 98-107 (Apr.) 1941. Google Scholar3. CoburnEvansNathan AFJJ: Studies on pathogenicity of Streptococcus pyogenes; experimental induction of respiratory tract infection in Swiss albino mice with group A hemolytic streptococcus, Brit. J. Exper. Path. 35: 270-278 (June) 1954. MedlineGoogle Scholar4. CoburnEvansNathan AFJJ: Studies on pathogenicity of Streptococcus pyogenes; factors which influence infectivity of group A hemolytic streptococcus in Swiss albino mice, Brit. J. Exper. Path. 35: 279-293 (June) 1954. MedlineGoogle Scholar5. SladeCoburnSimich HDAFL: Studies on the pathogenicity of Streptococcus pyogenes. III. 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HewittStewart DA: Some epidemiological aspects of acute rheumatism, Brit. J. Social Med. 6: 161-168 (July) 1952. MedlineGoogle Scholar20. CoburnTrulsonMoore AFMFLV: Ulteriori osservazioni sull'influenza della somministrazione di rosso d'uovo sulla suscettibilità dei bambini alla infezione reumatica, Minerva Medica 1: 1534-1536 (May) 1954. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Chappaqua, N. Y.*Presented as one of the James D. Bruce Memorial Lectures at the Thirty-eighth Annual Session of The American College of Physicians, Boston, Massachusetts, April 9, 1957.Requests for reprints should be addressed to Alvin F. Coburn, M.D., 14 Ludlow Drive, Chappaqua, N. Y. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDer rheumatische FormenkreisHautmanifestationen rheumatischer KrankheitenCurrent status of prophylaxis against rheumatic feverErkrankungen des EndokardÜber die Bedeutung von Streptokokkeninfektionen in der Pathogenese der akuten Polyarthritis und der akuten Neprithis 1 September 1957Volume 47, Issue 3Page: 402-417KeywordsEpidemiologyNutritionPathogenesisPharyngitisRheumatic feverStreptococcal infectionsStreptococcus pyogenes ePublished: 1 December 2008 Issue Published: 1 September 1957 PDF downloadLoading ...