AN EVALUATION OF THE USE OF QUINIDINE SULPHATE IN PERSISTENT AURICULAR FIBRILLATION
Authors: Cecil M. Kohn, Samuel A. Levine
Journal: Annals of Internal Medicine (1935)

Article1 February 1935AN EVALUATION OF THE USE OF QUINIDINE SULPHATE IN PERSISTENT AURICULAR FIBRILLATIONCECIL M. KOHN, M.D., SAMUEL A. LEVINE, M.D., F.A.C.P.CECIL M. KOHN, M.D., SAMUEL A. LEVINE, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-8-8-923 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSince the introduction of quinidine therapy as a treatment of auricular fibrillation by Frey1 in 1918, enthusiasm for its use has gradually waned. As with many new products in medicine early reports were very favorable, but careful observation over a period of years has shown that the use of the drug in permanent auricular fibrillation is warranted only in exceptional cases. It is indeed questionable whether any form of therapy to restore the normal rhythm is indicated in this condition.Time has shown that restoration of normal rhythm by quinidine is not apt to be permanent and it becomes evident...Bibliography1. FREY W: Über Vorhofflimern beim Menschen und seine Beseitigung durch Chinidin, Berl. klin. Wchnschr., 1918, lv, 450. Google Scholar2. LEVINEWILMAERS SAA: Is quinidine of value in treatment of auricular fibrillation? Boston Med. and Surg. Jr., 1925, cxcii, 388. CrossrefGoogle Scholar3. VIKOMARVINWHITE LEHMPD: Clinical report on use of quinidine sulphate, Arch. Int. Med., 1923, xxxi, 345. CrossrefGoogle Scholar4. WOLFFWHITE LPD: Auricular fibrillation; results of 7 years' experience with quinidine sulphate, Arch. Int. Med., 1929, xliii, 653. CrossrefGoogle Scholar5. WEISSMAN SA: Auricular fibrillation; ambulatory treatment with quinidine, Arch. Int. Med., 1932, xlix, 729. Google Scholar6. 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COSGRIFF, M.D.Auricular fibrillationBlood Quinidine Concentrations as a Guide in the Treatment of Cardiac ArrhythmiasAuricular fibrillation without other evidence of heart diseaseAuricular fibrillation of twenty-two months' duration, with return to normal sinus mechanism without the aid of quinidineEmbolism following thyroidectomy for hyperthyroidismAuricular fibrillation with congestive failure and no other evidence of organic heart diseaseMinute volume determinations in mitral stenosis during auricular fibrillation and after restoration of normal rhythm 1 February 1935Volume 8, Issue 8Page: 923-938KeywordsAtrial fibrillationDrugs ePublished: 1 December 2008 Issue Published: 1 February 1935 PDF downloadLoading ...