ELEVATED SERUM PANCREATIC ENZYME VALUES WITHOUT PRIMARY INTRINSIC PANCREATIC DISEASE
Authors: E C RAFFENSPERGER
Journal: Annals of Internal Medicine (1951)

Article1 August 1951ELEVATED SERUM PANCREATIC ENZYME VALUES WITHOUT PRIMARY INTRINSIC PANCREATIC DISEASEEDWARD C. RAFFENSPERGER, M.D., F.A.C.P.EDWARD C. RAFFENSPERGER, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-35-2-342 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIt has long been appreciated that the Cherry and Crandall1 modification of the Loevenhart method for determining serum lipase activity, and the Somogyi2 method for determining serum amylase activity, are valuable laboratory procedures for studying intrinsic pancreatic disease. However, elevations of serum pancreatic enzymes in conditions other than intrinsic pancreatic disease occur. It is the purpose of this paper to review the literature on this subject and to report on 21 cases, all of which showed appreciable elevations of serum pancreatic enzyme activity without intrinsic pancreatic disease.The normal values of serum amylase and serum lipase determined by the methods...Bibliography1. CherryCrandall ISLA: The specificity of pancreatic lipase; its appearance in the blood after pancreatic injury, Am. J. Physiol. 100: 266 (April) 1932. CrossrefGoogle Scholar2. Somogyi M: Determination of serum amylase activity, Proc. Soc. Exper. Biol. and Med. 32: 538, 1934. CrossrefGoogle Scholar3. CrandallCherry LAIS: Blood amylase, diastase and esterase in multiple sclerosis, Arch. Neurol. and Psychiat. 27: 367, 1932. CrossrefGoogle Scholar4. SwanMyers KCHB: Experimental studies of serum lipase in multiple sclerosis, Arch. Neurol. and Psychiat. 38: 288, 1937. CrossrefGoogle Scholar5. 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Author, Article, and Disclosure InformationAffiliations: Harrisburg, Pennsylvania*Received for publication March 31, 1950.Material for this paper was compiled while the author was a research fellow in gastroenterology at the Graduate Hospital, University of Pennsylvania. Aided by the Julia M. Keim Research Foundation of the University of Pennsylvania. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byValidade da amilasemia e da lipasemia no diagnóstico diferencial entre pancreatite aguda/crônica agudizada e outras causas de dor abdominal agudaClinical significance of elevated serum and urine amylase levels in patients with appendicitisHuman serum amylase: a brief biochemical evaluationComplications of Infectious MononucleosisSome Problems in the Diagnosis of Pancreatic DiseaseFRANK P. BROOKS, M.D., F.A.C.P.Jaundice, pancreatitis, azotemia, pneumomediastinum and psychotic behavior due to arteriomesenteric occlusionDie akuten Erkrankungen der Bauchspeicheldrüse, unter besonderer Berücksichtigung der leichteren Formen und ihrer Bedeutung für die ChirurgieThe plasma amylaseAcute pancreatitis associated with congenital cyst of the common bile ductThe Significance of Hyperamylasaemia in SurgicalconditionsPankreasAcute pancreatitisExocrine pancreatic secretionAcute PancreatitisEXTENSIVE FIBROPLASTIC PERITONITIS SECONDARY TO PROTRACTED ACUTE PANCREATITIS*DAVID B. SNOW, M.D.Pancreatitis, Medical AspectsAcute pancreatitisLABORATORY PROCEDURES IN THE DIAGNOSIS OF DISEASES OF THE PANCREAS 1The Pancreas: Contributions of Clinical Interest In 1951 1 August 1951Volume 35, Issue 2Page: 342-351KeywordsEnzymesGraduate medical educationLipasesPancreatic diseasesResearch laboratories Issue Published: 1 August 1951 PDF downloadLoading ...