PERIPHERAL NEUROPATHY IN MYXEDEMA
Authors: L E CREVASSE, R B LOGUE
Journal: Annals of Internal Medicine (1959)

Article1 June 1959PERIPHERAL NEUROPATHY IN MYXEDEMALAMAR E. CREVASSE, M.D., R. BRUCE LOGUE, M.D., F.A.C.P.LAMAR E. CREVASSE, M.D., R. BRUCE LOGUE, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-50-6-1433 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptDespite the fact that myxedema is a time-worn subject, it is so insidious and protean in its manifestations that even today the average duration of symptoms prior to recognition is 4.8 years.1A frequent but poorly appreciated manifestation is that of myxedematous peripheral neuropathy. This complication has been commented upon infrequently and vaguely in the past.2, 3, 4In our recent clinical experience with more than 250 patients treated with radioactive iodine to induce myxedema for its beneficial effects on cardiovascular diseases,5we have been impressed by the high incidence of distressing symptoms related to peripheral neuropathy. To determine its...Bibliography1. CrevasseDorneyPoole LERSO: Errors in diagnosis and treatment of myxedema: a critical review of 65 cases, presented at the Scientific Sessions, Fulton County Medical Society, May 8, 1958. Google Scholar2. Harrell GT: Myxedema, South. M. J. 45: 113, 1952. CrossrefMedlineGoogle Scholar3. CurrierBrink FPJR: Multiple neuritis and hypothyroidism, Dis. Nerv. System 9: 144, 1948. MedlineGoogle Scholar4. Goldblatt S: Pallhypesthesia—depression of the appreciation of vibration in trauma and in disease, Arch. Neurol. and Psychiat. 59: 292, 1948. CrossrefMedlineGoogle Scholar5. BlumgartFreedbertKurland HLASGD: Treatment of incapacitated euthyroid cardiac patients with radioactive iodine, J. A. M. A. 157: 1, 1955. CrossrefMedlineGoogle Scholar6. Chaney WC: Tendon reflexes in myxedema—a valuable aid in diagnosis, J. A. M. A. 82: 2013, 1924. CrossrefGoogle Scholar7. ScheinbergSteadBrannonWarren PEAESJV: Correlative observations on cerebral metabolism and cardiac output in myxedema, J. Clin. Investigation 29: 1139, 1950. CrossrefMedlineGoogle Scholar8. CrevasseLogueHurst LRBJW: Carotid artery insufficiency—early clinical recognition and treatment, Circulation, in press. Google Scholar9. ThompsonThompsonSilversDailey WOPKEMD: The cerebrospinal fluid in myxedema, Arch. Int. Med. 44: 368, 1929. CrossrefGoogle Scholar10. BrowningAtkinsWeiner TBRWH: Cerebral metabolic disturbances in hypothyroidism, Arch. Int. Med. 93: 938, 1954. CrossrefGoogle Scholar11. Asher R: Myxedema madness, Brit. M. J. 2: 555, 1949. CrossrefMedlineGoogle Scholar12. WaldsteinBronskyShrifterOlster SSDHBYT: The electromyogram in myxedema, Arch. Int. Med. 101: 97, 1958. CrossrefGoogle Scholar13. Ingold AH: Tension output in hyperthyroid and hypothyroid muscles stimulated directly and indirectly, Thesis, 1956, University of Illinois, Chicago, cited by Waldstein et al.12 Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Atlanta, Georgia*Received for publication July 3, 1958.From the Department of Medicine, Emory University School of Medicine, Emory University, Georgia.†Formerly National Heart Institute Fellow; presently Instructor in Medicine, University of Florida School of Medicine, Gainesville, Florida.Requests for reprints should be addressed to R. Bruce Logue, M.D., Professor of Medicine. Emory University, Post Office Box 459, Atlanta 22, Georgia. 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The Significance of the Postural TestsNervous and muscular systems in myxedemaHypothyreosen — Strumen — ThyreoiditidenCEREBELLAR SYNDROME IN MYXŒDEMA 1 June 1959Volume 50, Issue 6Page: 1433-1437KeywordsAnemiaCardiac ablationHeartPeripheral neuropathyThyroid ePublished: 1 December 2008 Issue Published: 1 June 1959 PDF downloadLoading ...