THE INCIDENCE OF EPIDEMIC TYPHUS ANTIBODIES IN INDIVIDUALS BORN IN EASTERN EUROPE
Authors: G L SCHAEFER, M FRIEDMAN, C LEWIS
Journal: Annals of Internal Medicine (1955)

Article1 May 1955THE INCIDENCE OF EPIDEMIC TYPHUS ANTIBODIES IN INDIVIDUALS BORN IN EASTERN EUROPEGERSCHEN L. SCHAEFER, M.D., MURRAY FRIEDMAN, Ph.D., CHRISTEEN LEWISGERSCHEN L. SCHAEFER, M.D.Search for more papers by this author, MURRAY FRIEDMAN, Ph.D.Search for more papers by this author, CHRISTEEN LEWISSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-42-5-979 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSince Brill's original paper1in 1910, and the definitive work by Zinsser2that followed, many cases of Brill's disease have been reported in the medical literature.3-8With the increased influx of people born in Eastern European areas since World War II, and with the return of our armed forces from Korea, the question arises as to how many of these people have been in contact with typhus. The advent of definitive therapy with Aureomycin and other antibiotics4-7should make the recognition of Brill's disease at this time of even greater import. Sigel and his group9in Philadelphia conducted a serologic...Bibliography1. Brill NE: An acute infectious disease of unknown origin. A clinical study based on 221 cases, Am. J. M. Sc. 139: 484, 1910; Am. J. Med. 13: 533, 1952. CrossrefGoogle Scholar2. Zinsser H: Varieties of typhus virus and the epidemiology of the American form of European typhus fever (Brill's disease), Am. J. Hyg. 20: 513, 1934. Google Scholar3. SchoenbachBryerLong EGMSPH: Pharmacology and clinical trial of Aureomycin. Preliminary report, Ann. New York Acad. Sc. 51: 267, 1948. CrossrefMedlineGoogle Scholar4. BlumbergDoaneWeiss NJCLB: Brill's disease. Report of 3 cases with Aureomycin treatment in 2, New England J. Med. 241: 479, 1949. CrossrefMedlineGoogle Scholar5. Schoenbach EG: Aureomycin therapy of recrudescent epidemic typhus (Brill's disease), J. A. M. A. 139: 450, 1949. CrossrefMedlineGoogle Scholar6. MurrayBaehrShwartzmanMandelbaumRosenthalDoaneWeissCohenSnyder ESGGRANJCLBSJC: Brill's disease, J. A. M. A. 142: 1059, 1950. CrossrefGoogle Scholar7. MurrayPsornBrozDjakovicSielskiBrozLjupsaGaonPavlevicSnyder ESTVPSVFJRJC: Brill's disease. IV. Study of 26 cases in Yugoslavia, Am. J. Pub. Health 41: 1359, 1951. CrossrefGoogle Scholar8. KaminLakinSchaeferGoldin HNHSGLM: Typhus fever, Illinois M. J. 101: 320, 1952. MedlineGoogle Scholar9. SigelWeissBlumbergDoane MMLBNJC: Survey of epidemic typhus antibody levels in bloods of individuals born in Eastern and Central Europe and the United States, Am. J. M. Sc. 223: 429, 1952. CrossrefMedlineGoogle Scholar10. Plotz H: Complement fixation in rickettsial diseases, Science 97: 20, 1943. CrossrefMedlineGoogle Scholar11. DyerRumneichBadger REALF: A virus of typhus type derived from fleas collected from wild rats, Pub. Health Rep. 46: 334, 1931. CrossrefGoogle Scholar12. Dyer RE: Endemic typhus fever: susceptibility of woodchuck, house mice, meadow mice and white footed mice, Pub. Health Rep. 49: 723, 1934. CrossrefMedlineGoogle Scholar13. Brigham GD: Susceptibility of the opossum (Didelphis virginiana) to the endemic typhus, Pub. Health Rep. 51: 332, 1936. Google Scholar14. Brigham GD: Susceptibility of animals to endemic typhus fever, Pub. Health Rep. 52: 659, 1937. CrossrefMedlineGoogle Scholar15. Brigham GD: A strain of endemic typhus fever isolated from a field mouse, Pub. Health Rep. 52: 659, 1937. CrossrefMedlineGoogle Scholar16. IronsMurphyDavid JVJNDE: The distribution of endemic typhus in rats in Lavaca County, Texas, Pub. Health Rep. 63: 692, 1948. CrossrefMedlineGoogle Scholar17. MorlanHillSchubert HBELJH: Serologic survey for murine typhus infection in Southwest Georgia animals, Pub. Health Rep. 65: 57, 1950. CrossrefMedlineGoogle Scholar18. IronsBohlsThurmanMcGregor JVSWDCT: Probable role of the cat flea, Ctenocephalides felis, in transmission of murine typhus, Am. J. Trop. Med. 24: 359, 1944. CrossrefGoogle Scholar19. IronsBeckMurphy JVOJN: Fleas carrying endemic typhus rickettsiae found on nonmurine hosts, J. Bact. 51: 609, 1946. MedlineGoogle Scholar20. KeatonNashMurphyIrons RBJJNJV: Complement fixation tests for murine typhus on small mammals, Pub. Health Rep. 68: 28, 1953. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Chicago, Illinois*Received for publication August 16, 1954.From the Departments of Medicine and Pathology, Mount Sinai Hospital, and from the Mount Sinai Medical Research Foundation, Chicago.†This investigation was supported in part by the Rose Protus Social Service Club. Nextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byBuerger’s Disease May be a Chronic Rickettsial Infection with Superimposed Thrombosis: Literature Review and Efficacy of Doxycycline in Three PatientsIntracellular Infection and the Carrier StateÄtiologie und Epidemiologie der Rickettsiosen des MenschenBrill–Zinsser disease; the possibility of its occurrence in BritainANOTHER CASE OF BRILL-ZINSSER DISEASE IN BRITAIN 1 May 1955Volume 42, Issue 5Page: 979-982KeywordsAntibodiesArmed forcesHospital medicineTyphus ePublished: 1 December 2008 Issue Published: 1 May 1955 Copyright & PermissionsCopyright, 1955, by The American College of PhysiciansPDF downloadLoading ...