Relapsing Polychondritis
Authors: RONALD L. KAYE
Journal: Annals of Internal Medicine (1964)

Article1 April 1964Relapsing PolychondritisClinical and Pathologic Features in Fourteen CasesRONALD L. KAYE, M.D., DONALD A. SONES, M.D.RONALD L. KAYE, M.D., DONALD A. SONES, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-60-4-653 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptRelapsing polychondritis is characterized by the prominent inflammation of cartilaginous structures and, in this respect, differs from other connective tissue diseases. The inflammation typically involves the cartilages of the ears and nasal septum, although cartilages of the joints, larynx, trachea, epiglottis, ribs, thyroid, bronchi, and eustachian tube also may be involved. Ocular inflammation and a generalized systemic reaction often occur. There also may be evidence of involvement of the inner ear with auditory impairment, tinnitus, and vertigo. Anemia and an abnormal erythrocyte sedimentation rate are common.The syndrome has been reported infrequently but may be more common than heretofore recognized....References1. PEARSONKLINENEWCOMER CMHMVD: Relapsing polychondritis. New Eng. J. Med. 263: 51, 1960. CrossrefMedlineGoogle Scholar2. WIEDMANNCRANEGILL FEARRJ: Systemic chondromalacia (Von Meyenburg's disease): (A case report). Bull. Ayer Clin. Lab. 4: 45, 1959. MedlineGoogle Scholar3. DAVIESKELSALL HRAR: Atrophic polychondritis with the report of a case. Ann. Rheum. Dis. 20: 189, 1961. CrossrefMedlineGoogle Scholar4. BEAN WB: Chronic atrophic polychondritis. Sixth International Congress of Internal Medicine, Handbook, Basel, 1960, pp. 192-193. Google Scholar5. MCKUSICKGOODMAN VARM: Pinnal calcification: observations in systemic diseases not associated with disordered calcium metabolism. JAMA 179: 230, 1962. CrossrefGoogle Scholar6. KAPLANNORRISFREEMANBROWN HLJEBSWG: Relapsing polychondritis: report of a case. 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CrossrefMedlineGoogle Scholar14. DIFERRANTERICH NC: The determination of acid aminopolysaccharide in urine. J. Lab. Clin. Med. 48: 491, 1956. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Rochester, MinnesotaFrom the Mayo Clinic and Mayo Foundation, Rochester, Minnesota.Presented in part at the Meeting of the American Rheumatism Association, Atlantic City, New Jersey, June 13 and 14, 1963.Requests for reprints should be addressed to Mayo Clinic, Rochester, Minnesota.*For other possible cases of this condition see reports by Pearson and associates (1) and by Kahn and Kilbury (11) and case 3 of Middleton's report (12). 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