BIOCHEMICAL STUDIES IN MULTIPLE SCLEROSIS
Authors: H H JONES, H H JONES, L D BUNCH
Journal: Annals of Internal Medicine (1950)

Article1 October 1950BIOCHEMICAL STUDIES IN MULTIPLE SCLEROSISHAROLD H. JONES, M.D., F.A.C.P., HAROLD H. JONES JR., M.D., LEITHA D. BUNCH, M.A.HAROLD H. JONES, M.D., F.A.C.P., HAROLD H. JONES JR., M.D., LEITHA D. BUNCH, M.A.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-33-4-831 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptHe consideration of multiple sclerosis as a metabolic disease is not new. The literature, both European and American, throws little light, however, on the chemical changes in this syndrome. Jelliffe1in 1921 stated the possibility that the neurologic lesions were of metabolic origin. German investigators2, 3reported elevated serum cholesterol values. In this country Brickner4found abnormal lipolytic activity in the blood. Crandall and Cherry5noted the similarity between the lipase activity in multiple sclerosis and in liver diseases. 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Author, Article, and Disclosure InformationAffiliations: *Presented at the Thirty-First Annual Session of the American College of Physicians, Boston, April 18, 1950.From the H. L. Snyder Memorial Research Foundation, Winfield, Kansas.The authors wish to express their appreciation to Richard R. Howard, M.D., for the statistical analysis of the data, and to Sister M. Casimir for the determination of prothrombin time. 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