NEUTROPENIA SECONDARY TO TUBERCULOUS SPLENOMEGALY: REPORT OF A CASE
Authors: A Z CHAPMAN, P S REEDER, L A BAKER
Journal: Annals of Internal Medicine (1954)

Case Reports1 December 1954NEUTROPENIA SECONDARY TO TUBERCULOUS SPLENOMEGALY: REPORT OF A CASEA. ZERNE CHAPMAN, M.D., PAUL S. REEDER, M.D., LYLE A. BAKER, M.D., F.A.C.P.A. ZERNE CHAPMAN, M.D.Search for more papers by this author, PAUL S. REEDER, M.D.Search for more papers by this author, LYLE A. BAKER, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-41-6-1225 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThere are few satisfactions in medicine greater than that which comes from seeing a severe neutropenia permanently reverted to normal as a result of therapy. The antibiotics have saved the lives of many of these patients during their acute infections, but the ultimate aim is to return the granulocytes to normal in number and activity. The reversible neutropenias are frequently associated with splenomegaly in which splenectomy is often curative. Such a hypersplenic mechanism, associated with a tuberculous etiology, is not common and, when present, is usually found in the disseminated or miliary form of tuberculosis. The case presented is of...Bibliography1. BrownMasonLucia JWJLSP: Tuberculous splenomegaly, study of a case, Ann. Int. Med. 17: 519-528, 1942. LinkGoogle Scholar2. CoffeeLipton HDS: Primary tuberculosis of the spleen, Arch. Surg. 47: 478-482, 1943. CrossrefGoogle Scholar3. DameshekEstren WS: Medical progress: hematology, New England J. Med. 237: 434-480, 1947. CrossrefMedlineGoogle Scholar4. Dietz CR: Tuberculous splenomegaly in children, Arch. Pediat. 63: 168-173, 1946. MedlineGoogle Scholar5. Engelbreth-Holm J: A study of tuberculous splenomegaly and splenogenic controlling of the cell emission from the bone morrow, Am. J. M. Sc. 195: 32-47, 1938. CrossrefGoogle Scholar6. MeredithEarlyBecker HCJQW: Tuberculous splenomegaly with hypersplenism, report of a case, Blood 4: 1367-1373 (Dec.) 1949. CrossrefMedlineGoogle Scholar7. PriceJardine AERL: Primary tuberculosis of the spleen: its clinical resemblance to Banti's disease, Ann. Int. Med. 4: 1574-1583, 1931. LinkGoogle Scholar8. SolomanDoran HAWT: Primary tuberculosis of the spleen, New York J. Med. 39: 1288-1295, 1939. Google Scholar9. WeinerCarter JJRF: Acute thrombocytopenic purpura (hemorrhagic) associated with tuberculosis (miliary) of the spleen, Ann. Surg. 113: 57-61, 1941. CrossrefMedlineGoogle Scholar10. Winternitz MC: Tuberculosis of the spleen, Arch. Int. Med. 9: 680-697, 1912. CrossrefGoogle Scholar11. Wintrobe MM: Clinical hematology, 1951, Lea and Febiger, Philadelphia, pp. 929-943. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication February 10, 1954.From the Department of Medicine, Veterans Administration Hospital, Hines, Illinois. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byHematologic Changes in TuberculosisMacrophages and Their Disorders in ManDisorders of Mononuclear Phagocyte Proliferation, Maturation and FunctionDISSEMINATED INFECTION CAUSED BY MYCOBACTERIUM KANSASIIIndikationen zur Splenektomie bei Blutkrankheiten 1 December 1954Volume 41, Issue 6Page: 1225-1231KeywordsAntibioticsEtiologyGranulocytesHospital medicineNeutropeniaSplenectomySplenomegaly ePublished: 1 December 2008 Issue Published: 1 December 1954 PDF downloadLoading ...