Total Base In Gastric Contents And Gastric Secretion
Authors: Katherine M. Close
Journal: Annals of Internal Medicine (1929)

Article1 May 1929Total Base In Gastric Contents And Gastric SecretionKATHERINE M. CLOSE, M.D.KATHERINE M. CLOSE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-2-11-1185 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptStudies of the gastric juice have centered largely around the question of acidity and little attention has been paid to the base in the gastric secretion. Since Reaumur isolated the gastric juice and proved its solvent action on ingested food, gastric secretion has been the subject of extensive research. But Young's observation that the secretion is strongly acid, and Prout's that the acid is hydrochloric directed study to the acids with almost total indifference to the other constituents. It is only comparatively recently that anything has been done with regard to the determination of total chlorides. Inasmuch as the bases...Bibliography(1) APPERLY : The Mechanism of Hyperchlorhydria. Med. Jour. Australia, 1923, i, 33-37. CrossrefGoogle Scholar(2) BELLMACADAM JR: The Variations in Gastric Secretion of the Normal Individual. Quart. Jour. Med., 1923-1924, xvii, 215-221. Google Scholar(3) BOLDYREFF W: The Self-Regulation of the Acidity of the Gastric Contents and the Real Acidity of the Gastric Juice. Quart. Jour. Exper. Physiol., 1915, viii, 1-12. Google Scholar(4) COLLIP JB: On the Formation of Hydrochloric Acid in the Gastric Tubules of the Vertebrate Stomach. Toronto, University of Toronto, 1912, 44 pp. Google Scholar(5) DOBSON HV: The Quantitative Determination of Gastric Secretion. (Unpublished thesis.) Google Scholar(6) GAMBLEMCIVAR JLMA: Fixed Base in Gastric Juice. Proc. Soc. Exper. Biol. and Med., 1925-1926, xxiii, 439-443. Google Scholar(7) HARVEYBENSLEY CHRR: Upon the Formation of Hydrochloric Acid in the Foveole and on the Surface of the Gastric Mucous Membrane and the Non-Acid Character of the Contents of Gland Cells and Lumina. Biol. Bull., 1912, xxiii, 225-249. CrossrefGoogle Scholar(8) HARVEY SC: The Quantitative Determination of the Chlorides in the Urine. Arch. Int. Med., 1910, vi, 12-18. CrossrefGoogle Scholar(9) MALY R: Untersuchungen űber die Mittel zur Säurebildung im Organismus und űber einige Verhältnisse des Blutserums. Ztschr. f. physiol. Chem., 1877, i, 174-204. Google Scholar(10) PROUT W: On the Ultimate Composition of Simple Alimentary Substances; With Some Preliminary Remarks on the Analysis of Organized Bodies in General. Phil. Tr. Roy. Soc. London, 1827, part II. Google Scholar(11) REAUMUR RA: In: GARRISON, F. H.: An Introduction to the History of Medicine. Ed. 2, Philadelphia, W. B. Saunders Company, 1917, pp. 317-319. Google Scholar(12) STADIEROSS WCEC: A Micro Method for the Determination of Base in Blood and Serum and Other Biological Materials. Jour. Biol. Chem., 1925, lxv, 735-754. CrossrefGoogle Scholar(13) YOUNG JR: Quoted by GARRISON, F. H.: An Introduction to the History of Medicine. Ed. 2, Philadelphia, W. B. Saunders Company, 1917, p. 495. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Division of Medicine The Mayo Foundation Rochester, Minnesota*The work was done under the supervision of Dr. Leonard G. Rowntree and is one of three studies. One of the two studies which will be published later is on the quantitative determination of gastric secretion by Dr. H. V. Dobson, and the other on the quantitative study of the different bases in the gastric juice by Dr. Theodore Bliss.†Submitted for publication February 23, 1929.**This reaction does not occur in vitro. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe composition of pure gastric juiceSTUDIES IN GASTRIC SECRETIONSTUDIES IN GASTRIC SECRETION 1 May 1929Volume 2, Issue 11Page: 1185-1193KeywordsChloridesFoodHydrochloric acid ePublished: 1 December 2008 Issue Published: 1 May 1929 PDF downloadLoading ...