FAMILIAL ACHOLURIC JAUNDICE ASSOCIATED WITH BONE CHANGES
Authors: Eric L. Cooper
Journal: Annals of Internal Medicine (1941)

Article1 November 1941FAMILIAL ACHOLURIC JAUNDICE ASSOCIATED WITH BONE CHANGESERIC L. COOPER, M.D.ERIC L. COOPER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-15-5-858 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptFamilial acholuric jaundice, frequently called congenital hemolytic icterus, is a relatively uncommon disease. In a city of approximately one million inhabitants, Melbourne, Australia, there are at least three families known to be afflicted with this inherited blood dyscrasia.The family here recorded is apparently in no way connected with any of the families previously reported from Australia and the patients present rather unusual bone and facial abnormalities.In all, 10 individuals in three generations have been affected. Three case histories follow:CASE REPORTSCase 1. Myra B., a female aged 14 years, was admitted to hospital in 1921 after attacks...References1. DAWSON BE: Hume lectures on haemolytic icterus, Brit. Med. Jr., 1931, i, 963-966. Google Scholar2. BRANNAN D: Extramedullary hematopoiesis in anemias, Bull. Johns Hopkins Hosp., 1927, xli, 104-136. Google Scholar3. GLEANE HH: Jr. Path. and Bact., 1936, xlii, 538. Google Scholar4. MANDEVILLE FB: Roentgen-ray findings in erythroblastic anemia, Radiology, 1930, xv, 72-84. CrossrefGoogle Scholar5. GRINNAN AG: Roentgenologic bone changes in sickle cell and erythroblastic anemia, Am. Jr. Roentgenol., 1935, xxxiv, 297-309. Google Scholar6. LE WALD LT: Roentgen evidence of osseous manifestations in sickle cell (drepanocytic) anemia and in Mediterranean (erythroblastic) anemia, Radiology, 1932, xviii, 792-798. CrossrefGoogle Scholar7. WHIPPLEREEVESCOBB AORJCC: Atypical haemolytic anemia with splenomegaly in children, Ann. Surg., 1928, lxxxviii, 380-387. CrossrefGoogle Scholar8. COOLEY TB: Likenesses and contrasts in hemolytic anemias of childhood, Am. Jr. Dis. Child., 1928, xxxvi, 1256-1262. Google Scholar9. WILLIAMS HU: Human paleopathology, with some original observations on symmetrical osteoporosis of skull, Arch. Path., 1929, vii, 839-902. Google Scholar10. GÄNNSLEN M: Klin. Fortbild., 1936, iv, 607. Google Scholar11. FRIEDMAN LJ: Osseous changes in hemolytic icterus, Am. Jr. Roentgenol., 1928, xx, 440-444. Google Scholar12. WADESTEIGRAD RBJ: Splenomegalic jaundice with associated changes in skull, Med. Jr. Australia, 1928, ii, 530-532. CrossrefGoogle Scholar13. FEINGOLDCASE BFJT: Roentgenologic skull changes in the anemias of childhood. Report of a case. A few notes on similar findings among the skulls of Peruvian Indians, Am. Jr. Roentgenol., 1933, xxix, 194-202. Google Scholar14. ROSE CB: Some unusual x-ray findings in skulls, Radiology, 1929, xiii, 508-514. CrossrefGoogle Scholar15. VOGTDIAMOND ECLK: Congenital anemias, roentgenologically considered, Am. Jr. Roentgenol., 1930, xxiii, 625-630. Google Scholar16. COOLEYWITWERLEE TBERP: Anemia in children with splenomegaly and peculiar changes in bones; report of cases, Am. Jr. Dis. Child., 1927, xxxiv, 347-363. CrossrefGoogle Scholar17. BATYBLACKFANDIAMOND JMKDLK: Blood studies in infants and in children; erythroblastic anemia; clinical and pathologic study, Am. Jr. Dis. Child., 1932, xliii, 667-704. CrossrefGoogle Scholar18. GRAHAM GS: A case of sickle cell anemia with necropsy, Arch. Int. Med., 1924, xxxiv, 778-800. CrossrefGoogle Scholar19. COWEN SO: Familial haemolytic splenomegaly, Med. Jr. Australia, 1922, ii, 545-561. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Melbourne, Australia*Received for publication January 28, 1941. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byChanges in bone associated with cyanotic congenital cardiac disease 1 November 1941Volume 15, Issue 5Page: 858-868KeywordsBloodBone ePublished: 1 December 2008 Issue Published: 1 November 1941 PDF downloadLoading ...