ACUTE HEMOLYTIC ANEMIA COMPLICATING INFECTIOUS MONONUCLEOSIS: REPORT OF TWO CASES
Authors: D H APPELMAN, G B GORDON
Journal: Annals of Internal Medicine (1954)

Case Reports1 August 1954ACUTE HEMOLYTIC ANEMIA COMPLICATING INFECTIOUS MONONUCLEOSIS: REPORT OF TWO CASESDAVID H. APPELMAN, M.D., GEORGE B. GORDON, M.D.DAVID H. APPELMAN, M.D.Search for more papers by this author, GEORGE B. GORDON, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-41-2-371 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe development of acute hemolytic anemia during the course of infectious mononucleosis has only recently been reported.1-4Dameshek and Schwartz5had previously reported the occurrence of hemolytic anemia in a patient with infectious mononucleosis but in this instance, sulfadiazine had been administered. Ellis, Wollenman and Stetson1described the occurrence of acute hemolytic anemia in an illness resembling infectious mononucleosis in which autohemagglutinins, hemolysins and a positive Donath-Landsteiner test were found. In their case the heterophil antibody titer was markedly elevated initially, as were the hemagglutinin titers. Coincident with the fall in the heterophil antibody titer a decrease in serum hemagglutinins...Bibliography1. EllisWollenmanStetson LBOJRP: Autohemagglutinins and hemolysins with hemoglobinuria and acute hemolytic anemia in an illness resembling infectious mononucleosis, Blood 3: 419, 1948. CrossrefMedlineGoogle Scholar2. AppelmanMorrison DHMM: Concomitant infectious mononucleosis and hemolytic icterus, Blood 4: 186, 1949. CrossrefMedlineGoogle Scholar3. WilsonWardGray SJCELW: Infectious lymphadenosis (mononucleosis) and hemolytic anemia in a Negro, Blood 4: 189, 1949. CrossrefMedlineGoogle Scholar4. SawitskyPappsWiener AJPLM: The demonstration of antibody in acute hemolytic anemia complicating infectious mononucleosis, Am. J. Med. 8: 260, 1950. CrossrefMedlineGoogle Scholar5. DameshekSchwartz WS: Acute hemolytic anemia, Medicine 19: 231, 1940. CrossrefGoogle Scholar6. Mackenzie GM: Observations on paroxysmal hemoglobinuria, J. Clin. Investigation 7: 27, 1929. CrossrefMedlineGoogle Scholar7. HamHorack GCHM: Chronic hemolytic anemia with paroxysmal nocturnal hemoglobinuria, Arch. Int. Med. 67: 735, 1941. CrossrefGoogle Scholar8. DolgopolHusson VBGS: Infectious mononucleosis with neurological complications, report of a fatal case, Arch. Int. Med. 83: 179, 1949. CrossrefGoogle Scholar9. Wintrobe MM: Clinical hematology, 1951, Lea and Febiger, Philadelphia. Google Scholar10. ReedHelwig JTFC: Infectious mononucleosis. An analysis of 300 cases with three characterized by rare hematological features, Arch. Int. Med. 95: 376, 1945. CrossrefGoogle Scholar11. DoranWeisberger JKAS: The use of ACTH in infectious mononucleosis, Ann. Int. Med. 38: 1058, 1953. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Brooklyn, New York*Received for publication November 4, 1953.From the Department of Medicine, The Beth-El Hospital, Brooklyn, N. Y. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySEVERE ACUTE H/EMOLYTIC ANÆMIA COMPLICATING INFECTIOUS MONONUCLEOSISAplastic Anaemia Complicating Infectious MononucleosisTreatment of Infectious MononucleosisHAROLD R. SCHUMACHER, WILLIAM A. JACOBSON, CARL R. BEMILLER, M.D.Serologie und Klinik der autoimmunhämolytischen ErkrankungenINFECTIOUS MONONUCLEOSIS WITH JAUNDICE AND ABDOMINAL PAIN AS PRESENTING COMPLAINTS: REPORT OF CASE*DUNCAN C. WORMER, M.D., WILLIAM J. MARTIN, M.D., ERIC E. WOLLAEGER, M.D.Infectious mononucleosis hepatitisCOMPLICATIONS OF INFECTIOUS MONONUCLEOSIS*JASON NED SMITH JR., M.D.Symptomatic and hemopathic hemolytic anemia 1 August 1954Volume 41, Issue 2Page: 371-376KeywordsFallsHemolytic anemiaHospital medicine ePublished: 1 December 2008 Issue Published: 1 August 1954 PDF downloadLoading ...