FUADIN THERAPY OF SCHISTOSOMIASIS ASSOCIATED WITH VENTRICULAR TACHYCARDIA AND DEATH: A CASE REPORT
Authors: R SCHICK, A B RITTERBAND, A H LIEBERMAN
Journal: Annals of Internal Medicine (1957)

Case Reports1 February 1957FUADIN THERAPY OF SCHISTOSOMIASIS ASSOCIATED WITH VENTRICULAR TACHYCARDIA AND DEATH: A CASE REPORTROBERT SCHICK, M.D., ARNOLD B. RITTERBAND, M.D., AMOS H. LIEBERMAN, M.D.ROBERT SCHICK, M.D.Search for more papers by this author, ARNOLD B. RITTERBAND, M.D.Search for more papers by this author, AMOS H. LIEBERMAN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-46-2-392 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe heavy influx of Puerto Rican immigrants into the United States during the last 15 years has focused increasing attention on the therapy of parasitic infestations. Schistosomiasis constitutes a particular problem because it may be associated with portal cirrhosis, splenomegaly with hypersplenism, and esophageal varices. The schistosomal parasite may have an astonishing longevity. Viable ova have been reported1 in the rectal mucosa of patients as long as 25 to 30 years after they have left areas endemic for schistosomiasis with no possibility of reinfection.In view of the increasing use of the organic antimony compound Fuadin in the therapy of...Bibliography1. Wallerstein RS: Longevity of Schistosoma mansoni: observations based on a case, Am. J. Trop. Med. 29: 717, 1949. CrossrefMedlineGoogle Scholar2. BraunLuskyCalvery HALMHO: The effect of 2,3-dimercaptopropanol (BAL) in the therapy of poisoning by compounds of antimony, bismuth, chromium, mercury and nickel, J. Pharmacol. and Exper. Therap. 87 (Suppl.): 119, 1946. MedlineGoogle Scholar3. EagleGermuthMagnersonFleischman HFGHR: The protective action of BAL in experimental antimony poisoning, J. Pharmacol. and Exper. Therap. 89: 196, 1947. MedlineGoogle Scholar4. GamillSouthamVan Dyke JFCMHB: The effect of 2,3-dimercaptopropanol (BAL) on acute poisoning by tervalent and quinquevalent antimonial drugs, Proc. Soc. Exper. Biol. and Med. 64: 13, 1947. CrossrefMedlineGoogle Scholar5. BartterCowieMostNessForbush FCDBHATS: The fate of radioactive tartar emetic administered to human subjects, Am. J. Trop. Med. 27: 403, 1947. CrossrefGoogle Scholar6. OttoMarenBrown GFTHHW: Blood levels and excretion rates of antimony in persons receiving trivalent and pentavalent antimonials, Am. J. Hyg. 46: 193, 1947. MedlineGoogle Scholar7. Bahner CT: Localization of antimony in blood, Proc. Soc. Exper. Biol. and Med. 86: 371, 1954. CrossrefMedlineGoogle Scholar8. BradyLawtonCowieAndrewsNessOgden FJAHDBHLATGE: Localization of trivalent radioactive antimony following intravenous administration to dogs infected with Dirofilaria immitis , Am. J. Trop. Med. 25: 103, 1945. CrossrefGoogle Scholar9. GelhornTupikovaVan Dyke ANAHB: The tissue distribution and excretion of four organic antimonials after single or repeated injections to normal hamsters, J. Pharmacol. and Exper. Therap. 87: 169, 1946. MedlineGoogle Scholar10. Hassan A: Distribution of antimony in body organs following administration of therapeutic antimony, J. Egyptian M. A. 21: 123, 1938. Google Scholar11. LippincottEllerbrookMason SWMRR: A study of the distribution and fate of antimony when used as tartar emetic and Fuadin in the treatment of American soldier with Schistosomiasis japonica , J. Clin. Investigation 26: 370, 1947. CrossrefGoogle Scholar12. PesiganBasaca-SevillaPangilinanSanielGarciaBanzonBeltranPutongMillar TPVMVVFEGTAPBCA: Evaluation of Fuadin therapy in Schistosomiasis japonica , J. Philadelphia M. A. 27: 234, 1951. MedlineGoogle Scholar13. Burtner OW: Schistosomiasis japonica in American soldiers in the Philippines, J. Philadelphia M. A. 26: 537, 1950. MedlineGoogle Scholar14. CleveLangsjoenHensler EAPHNM: The toxic effect of tartar emetic in treatment of schistosomiasis, Am. J. M. Sc. 229: 74, 1955. CrossrefMedlineGoogle Scholar15. GoodmanGilman LSA: The pharmacological basis of therapeutics, 2nd Ed., 1955, The Macmillan Company, New York, p. 973. Google Scholar16. PesiganBeltran TPAM: Studies of liver function tests in Schistosomiasis japonica , J. Philadelphia M. A. 27: 220, 1951. MedlineGoogle Scholar17. SuarezSantiago-StevensonHernandez-Morales RMDF: Electrocardiographic changes during anthiomaline treatment of schistosomiasis, Am. Heart J. 36: 923, 1948. CrossrefMedlineGoogle Scholar18. MostKaneLavietesSchroederBehmBlumKatzinHyman HCAPHEFALBJM: Schistosomiasis japonica in American military personnel: clinical studies of 600 cases during first year after infection, Am. J. Trop. Med. 30: 239, 1950. CrossrefMedlineGoogle Scholar19. Tarr L: Effects of the antimony compounds, Fuadin, and tartar emetic on the electrocardiogram of man: a study of the changes encountered in 141 patients treated for schistosomiasis, Ann. Int. Med. 27: 970, 1947. LinkGoogle Scholar20. BeaserRodriguez-Molina SBR: Electrocardiographic changes occurring during treatment with Fuadin solution, Am. Heart J. 32: 634, 1946. CrossrefMedlineGoogle Scholar21. MainzerKrause FM: Changes of the electrocardiogram appearing during antimony treatment, Tr. Roy. Soc. Trop. Med. and Hyg. 33: 405, 1940. CrossrefGoogle Scholar22. Khalil BM: Individual variation in the excretion of drugs as an important factor in their therapeutic results. A practical method for detecting the schistosomiasis cases with so-called idiosyncrasy to antimony to avoid fatalities and complications, J. Egyptian M. A. 19: 285, 1936. Google Scholar23. AlvesBlair WDW: Schistosomiasis: a review of work in Southern Rhodesia in 1946, South African M. J. 212: 352, 1947. Google Scholar24. BriegerSemischStasneyPiatnek HCWJDA: Industrial antimony poisoning, Indust. Med. and Surg. 23: 521, 1954. MedlineGoogle Scholar25. SpingarnEdelman CLMH: Observations on the treatment of Schistosomiasis mansoni with Fuadin, Ann. Int. Med. 42: 1198-1205, 1955. LinkGoogle Scholar26. Most H, cited by Spingarn, C. L., and Edelman, M. H.25 Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication September 17, 1955.From the Medical Service of The Mount Sinai Hospital.Requests for reprints should be addressed to Robert Schick, M.D., Glenn Dale Hospital, Glenn Dale, Md. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byObservations on the treatment of schistosomiasis mansoni with antimony dimercaptosuccinate (TWSb)Paroxysmal ventricular tachycardia associated with myxedema a case reportA myocardial syndromeMyokarditis und weitere MyokardiopathienRecurrent ventricular tachycardia as the chief manifestation of myocarditis of unknown etiology 1 February 1957Volume 46, Issue 2Page: 392-403KeywordsCirrhosisElectrocardiographyHypotensionMedical servicesMucous membranesPneumoniaSchistosomiasisSplenomegalyTachycardiaVentricular tachycardia ePublished: 1 December 2008 Issue Published: 1 February 1957 PDF downloadLoading ...