Accelerated Thromboplastin Generation in Acute Arterial Occlusion Complicating Arteriosclerosis Obliterans
Authors: JOHN A. SPITTELL
Journal: Annals of Internal Medicine (1961)

Article1 November 1961Accelerated Thromboplastin Generation in Acute Arterial Occlusion Complicating Arteriosclerosis ObliteransJOHN A. SPITTELL JR., M.D., CHRIS A. PASCUZZI, M.D., JOHN H. THOMPSON JR., PH.D., CHARLES A. OWEN JR., M.D.JOHN A. SPITTELL JR., M.D.Search for more papers by this author, CHRIS A. PASCUZZI, M.D.Search for more papers by this author, JOHN H. THOMPSON JR., PH.D.Search for more papers by this author, CHARLES A. OWEN JR., M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-55-5-765 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptWhat part, if any, thrombosis plays in the development of arteriosclerosis is still unsettled; however, there is agreement that thrombosis is the terminal event in the arterial occlusion of the extremity affected by arteriosclerosis obliterans. Pathologic study of the arteries of limbs amputated for advanced arteriosclerosis obliterans has shown that thrombosis is responsible for at least part of the arterial occlusion in all (1).Within the group of persons with arteriosclerosis obliterans are patients whose course is a chronic one, their only symptom being intermittent claudication; the course of other patients, however, is complicated by sudden arterial occlusion often resulting in...References1. BARKER NW: Changes in the coagulability of the blood in arteriosclerosis obliterans of the extremities. Amer. Heart J. 35: 856, 1948. CrossrefMedlineGoogle Scholar2. HAGEDORNBARKER ABNW: Response of persons with and without intravascular thrombosis to a heparin tolerance test. Amer. Heart J. 35: 603, 1948. CrossrefMedlineGoogle Scholar3. ROSENBAUMBARKER EENW: A test of the coagulation time of blood heparinized in vitro: studies of normal subjects and of patients with intravascular thrombosis. J. Lab. Clin. Med. 33: 1342, 1948. 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MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: JOHN A. SPITTELLJR., M.D.; CHRIS A. PASCUZZI, M.D.; JOHN H. THOMPSONJR., PH.D.; CHARLES A. OWENJR., M.D.Affiliations: Rochester, MinnesotaPresented at the Forty-second Annual Session of The American College of Physicians, Miami Beach, Florida, May 8-12, 1961.Supported in part by Grant H-5008, United States Public Health Service, National Institutes of Health.Requests for reprints should be addressed to Mayo Clinic, Rochester, Minn. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byBor und spezielle BorverbindungenBlood Coagulation Changes in DiseaseComparative Studies of Blood Coagulation and Platelet Aggregation in Patients with Cancer and Nonmalignant DiseasesRICHARD B. DAVIS, M.D., PH.D., F.A.C.P., ATHANASIOS THEOLOGIDES, M.D., PH.D., B. J. KENNEDY, M.D., F.A.C.P.Hypercoagulability with MalignancyEffects of enovid on blood clotting factorsHypercoagulability Associated with Malignant Disease and with the Postoperative State Evidence for Elevated Levels of Antihemophilic GlobulinMELVIN A. AMUNDSEN, M.D., JOHN A. SPITTELL JR., M.D., JOHN H. THOMPSON JR., PH.D., CHARLES A. OWEN JR., M.D.Blood Coagulation and Intravascular Thrombosis 1 November 1961Volume 55, Issue 5Page: 765-771KeywordsAnticoagulantsArteriesMedical servicesThrombosis ePublished: 1 December 2008 Issue Published: 1 November 1961 PDF downloadLoading ...