Recombinant DNA Methods for Prenatal Diagnosis
Authors: C. THOMAS CASKEY
Journal: Annals of Internal Medicine (1983)

Editorials1 November 1983Recombinant DNA Methods for Prenatal DiagnosisC. THOMAS CASKEY, M.D.C. THOMAS CASKEY, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-99-5-718 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAn estimated 30 000 patients in the U. S. used prenatal diagnosis services in 1982. Even greater use of these services is likely to develop as the new recombinant DNA methods widen the spectrum of diseases amenable to prenatal diagnosis. Recombinant methods examine the gene (DNA), not its product (a protein). Any nucleated cell (aminocytes or chorionic villi) can be used with these methods, which gets around the impossibility of studying inaccessible specialized tissues in the fetus, such as blood or liver. 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Author, Article, and Disclosure InformationAffiliations: Baylor College of Medicine Houston, Texas PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 November 1983Volume 99, Issue 5Page: 718-719KeywordsBlood cellsChorionic villus samplingDNAFetusesLiverPregnancyPrenatal diagnosisRecombinant proteins Issue Published: 1 November 1983 PDF DownloadLoading ...