REGIONAL ENTERITIS. I. CLINICAL ASPECTS AND DIAGNOSIS IN 100 PATIENTS
Authors: J E DAFFNER, C H BROWN
Journal: Annals of Internal Medicine (1958)

Article1 September 1958REGIONAL ENTERITIS. I. CLINICAL ASPECTS AND DIAGNOSIS IN 100 PATIENTSJOHN E. DAFFNER, M.D., CHARLES H. BROWN, M.D., F.A.C.P.JOHN E. DAFFNER, M.D.Search for more papers by this author, CHARLES H. BROWN, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-49-3-580 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlthough regional ileitis was recognized as a clinical entity by Crohn, Ginsburg and Oppenheimer1 26 years ago, much remains unknown concerning the etiology, pathogenesis and treatment of the disease.Regional ileitis was defined by Crohn, Ginsburg and Oppenheimer1as a recurrent granulomatous disease mainly affecting young adults. In the acute inflammatory phase, ulcerative lesions are prominent; later, thickening of the mucosa, scarring, intestinal obstruction and fistulas may be present. The terminal ileum chiefly is involved, although lesions may be present elsewhere in the small intestine. Regional enteritis may cross the ileocecal valve and involve the colon (ileocolitis). The disease is...Bibliography1. CrohnGinsburgOppenheimer BBLGD: Regional ileitis; pathologic and clinical entity, J. A. M. A. 99: 1323, 1932. CrossrefGoogle Scholar2. Crohn BB: Regional ileitis, 1949, Grune & Stratton, New York, p. 229. Google Scholar3. RogersHaserick FJJR: Value of Kveim test as diagnostic measure in sarcoidosis: preliminary report, Cleveland Clin. Quart. 21: 79, 1954. CrossrefGoogle Scholar4. Van PatterBargenDockertyFeldmanMayoWaugh WNJAMBWHCWJM: Regional enteritis, Gastroenterology 26: 347, 1954. CrossrefMedlineGoogle Scholar5. RossmillerMessenger HRHM: Regional enteritis: diagnosis and treatment, a study of 55 cases over a nine-year period, M. Clin. North America 32: 419, 1948. CrossrefMedlineGoogle Scholar6. MeyersRubleAshley SGPELB: Clinical course of regional enteritis, personal communication, presented at the American Gastroenterologic Association meeting, Colorado Springs, May 17-18, 1957. Google Scholar7. Yarnis H: Symposium on regional ileitis syndrome of combined ileocolitis, J. Mt. Sinai Hosp. 22: 159, 1955. MedlineGoogle Scholar8. BrownSims CHJR: Regional enteritis involving the duodenum: report of two cases, Cleveland Clin. Quart. 21: 95, 1954. CrossrefGoogle Scholar9. MarshakWolf RHHM: Roentgen findings in regional enteritis, Am. J. Roentgenol. 74: 1000, 1955. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Cleveland, Ohio*Received for publication September 3, 1957.From the Department of Gastroenterology, The Cleveland Clinic Foundation, and The Frank E. Bunts Educational Institute, Cleveland, Ohio.†This paper is based on the thesis that was submitted by Dr. Daffner in partial fulfillment of his fellowship requirements and that won the Lower Prize from The Frank E. Bunts Educational Institute in 1957.Requests for reprints should be addressed to Charles H. Brown, M.D., Department of Gastroenterology, Cleveland Clinic, 2020 East Ninety-third Street, Cleveland 6, Ohio. 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DEREN, M.D., JEROME G. PORUSH, M.D., MARVIN F. LEVITT, M.D., F.A.C.P., MANSHO T. KHILNANI, M.D.Crohn's Disease (Regional Enteritis) of the Large Intestine and its Distinction from Ulcerative ColitisSurgical Treatment of Regional EnteritisSpondylitis in chronic ulcerative colitisInflammatory diseases of the large and small intestine 1 September 1958Volume 49, Issue 3Page: 580-594KeywordsEnteritisFistulasIleumLesionsMucous membranesNeuromuscular diseasesPathogenesisSmall intestineUlcerative colitisYoung adults ePublished: 1 December 2008 Issue Published: 1 September 1958 PDF downloadLoading ...