THE PATHOGENESIS OF LUPUS ERYTHEMATOSUS AND ALLIED CONDITIONS
Authors: P KLEMPERER
Journal: Annals of Internal Medicine (1948)

Article1 January 1948THE PATHOGENESIS OF LUPUS ERYTHEMATOSUS AND ALLIED CONDITIONSPAUL KLEMPERER, M.D.PAUL KLEMPERER, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-28-1-1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn 1872 when Kaposi1published his first report of acute lupus erythematosus, medicine was still dominated by the pathologic-anatomic doctrine that disease is the result of alterations of bodily structure. Today the study of pathogenesis aims at a full comprehension and integration of all the factors of the external and internal environment which bring about that altered state of life, called disease. Inquiry into the genesis of a disease can no longer be content with the mere perception of structural alterations. Yet the definition of most maladies still depends upon an exact knowledge of characteristic organ and tissue changes. 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