HEMODYNAMIC CHANGES FOLLOWING ACUTE MYOCARDIAL INFARCTION USING THE DYE INJECTION METHOD FOR CARDIAC OUTPUT DETERMINATION
Authors: J F GAMMILL, J J APPLEGARTH, C E REED, J D FERNALD, A J ANTENUCCI
Journal: Annals of Internal Medicine (1955)

Article1 July 1955HEMODYNAMIC CHANGES FOLLOWING ACUTE MYOCARDIAL INFARCTION USING THE DYE INJECTION METHOD FOR CARDIAC OUTPUT DETERMINATIONJAMES F. GAMMILL, M.D., J. JERROLD APPLEGARTH, M.D., CHARLES E. REED, M.D., JOHN D. FERNALD, M.D., ARTHUR J. ANTENUCCI, M.D., F.A.C.P.JAMES F. GAMMILL, M.D., J. JERROLD APPLEGARTH, M.D., CHARLES E. REED, M.D., JOHN D. FERNALD, M.D., ARTHUR J. ANTENUCCI, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-43-1-100 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptQuantitative studies of hemodynamic changes following acute myocardial infarction in patients have not been performed until recent years,1and the over-all experience is quite limited.2, 3, 4In this series of 39 patients the diagnosis of acute myocardial infarction was clearly established from review of the history, physical findings and serial electrocardiograms. The dye injection method of determining cardiac output as described by Hamilton and associates5, 6was used, since it had been established that this was a safe and reliable method and could be performed without interfering with therapy and without moving the patient from his bed. In the...Bibliography1. FreisSchnaperJohnsonSchreiner EDHWRLGE: Hemodynamic alterations in acute myocardial infarction. I. Cardiac output, mean arterial pressure, total peripheral resistance, "central" and total blood volumes, venous pressure, and average circulation time, J. Clin. Investigation 31: 131, 1952. CrossrefMedlineGoogle Scholar2. GilbertAldrichAnderson RPSLL: Cardiac output in acute myocardial infarction, J. Clin. Investigation 30: 640, 1951 (abstract). Google Scholar3. GrishmanMaster AAM: Cardiac output in coronary occlusion studies by the Wezler-Boger physical method, Proc. Soc. Exper. Biol. and Med. 48: 207, 1941. CrossrefGoogle Scholar4. StarrWood IFC: Studies with the ballistocardiograph in acute cardiac infarction and chronic angina pectoris, Am. Heart J. 25: 81, 1943. CrossrefGoogle Scholar5. HamiltonRileyAttyahCournandFowellHimmelsteinNobleRemingtonRichardsWheelerWitham WFRLAMADMARPJWDWNCAC: Comparison of the Fick and dye injection methods of measuring the cardiac output in man, Am. J. Physiol. 153: 309, 1948. CrossrefMedlineGoogle Scholar6. HamiltonMooreKinsmanSpurling WFJWJMRG: Studies on the circulation. IV. Further analysis of the injection method, and of changes in hemodynamics under physiological and pathological conditions, Am. J. Physiol. 99: 534, 1931-32. CrossrefGoogle Scholar7. WerkoLagerlofBuchtWehleHolmgren LHHBA: Comparison of the Fick and Hamilton methods for the determination of cardiac output in man, Scandinav. J. Clin. and Lab. Invest. 1: 109, 1949. CrossrefGoogle Scholar8. NewmanMerrellGenecinMilnorMcKeever EVMAWRWP: The dye dilution method for describing the central circulation. An analysis of factors shaping the time-concentration curves, Circulation 4: 735, 1951. CrossrefMedlineGoogle Scholar9. Gregerson MI: A practical method for the determination of blood volume with the dye T-1824, J. Lab. and Clin. Med. 29: 1266, 1944. Google Scholar10. BestTaylor CHNB: The physiological basis of medical practice, 5th Ed., 1950, Williams and Wilkins Co., Baltimore. Google Scholar11. EbertBordenWellsWilson RVCWHSRH: Studies of the pulmonary circulation. I. The circulation time from the pulmonary artery to the femoral artery and the quantity of blood in the lungs in normal individuals, J. Clin. Investigation 28: 1134, 1949. CrossrefGoogle Scholar12. KopelmanLee HGd: The intrathoracic blood volume in mitral stenosis and left ventricular failure, Clin. Sc. 10: 383, 1951. MedlineGoogle Scholar13. Wiggers CJ: Dynamics of ventricular contraction under abnormal conditions, Circulation 5: 321, 1952. CrossrefMedlineGoogle Scholar14. GrossMendlowitzSchauer LMG: Hemodynamic studies in experimental coronary occlusion. I. Open chest experiments, Am. Heart J. 13: 647, 1937. CrossrefGoogle Scholar15. MendlowitzSchauerGross MGL: Hemodynamic studies in experimental coronary occlusion. II. Closed chest experiments, Am. Heart J. 13: 664, 1937. CrossrefGoogle Scholar16. Orias O: The dynamic changes in the ventricles following ligation of the ramus descendens anterior, Am. J. Physiol. 100: 629, 1932. CrossrefGoogle Scholar17. Wiggers CJ: The functional consequences of coronary occlusion, Ann. Int. Med. 23: 158, 1945. LinkGoogle Scholar18. PattersonStarling SWEH: On the mechanical factors which determine the output of the ventricles, J. Physiol. 48: 357, 1914. CrossrefMedlineGoogle Scholar19. Wiggers CJ: Determinants of cardiac performance, Circulation 4: 485, 1951. CrossrefMedlineGoogle Scholar20. FishbergHitzigKing AMWMFH: Circulatory dynamics in myocardial infarction, Arch. Int. Med. 54: 997, 1934. CrossrefGoogle Scholar21. Selzer A: Circulation in acute myocardial infarction, Arch. Int. Med. 76: 54, 1945. CrossrefGoogle Scholar22. AgressRosenburgSchneidermanBrotman CMMAEJ: Blood volume studies in shock resulting from myocardial infarction. I. Studies with Evans blue dye (T-1824), J. Clin. Investigation 29: 1267, 1950. CrossrefMedlineGoogle Scholar23. Boyer NH: Medical progress; cardiogenic shock, New England J. Med. 230: 226, 1944. CrossrefGoogle Scholar24. SteadEbert EARV: Shock syndrome produced by failure of the heart, Arch. Int. Med. 69: 369, 1942. CrossrefGoogle Scholar25. LandisHortenstine EMJC: Functional significance of venous blood pressure, Physiol. Rev. 30: 1, 1950. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication December 14, 1954.From the Division of Medicine, The Roosevelt Hospital, New York, N. Y.†With the technical assistance of THERESA LO PRESTI, B.S. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byElevated myocardial wall stress after percutaneous coronary intervention in acute ST elevation myocardial infraction is associated with increased mortalityExperimental myocardial infarctionHemodynamic Effects of Acute Myocardial InfarctionEvolution of Abnormalities in Left Ventricular Function after Acute Myocardial InfarctionReferencesHemodynamic Evaluation of Left Ventricular Function in Shock Complicating Myocardial InfarctionLeft Ventricular Function in Acute Myocardial Infarction and its Clinical SignificancePathophysiology of ischemic heart diseaseThe value and limitations of coronary care monitoringHemodynamic Findings in 123 Patients with Acute Myocardial Infarction on AdmissionExperimental myocardial infarction. III. Recovery of left ventricular function in the healing phase. Contribution of increased fiber shortening in noninfarcted myocardiumLeft ventricular function during the early and late stages of scar formation following experimental myocardial infarctionREFERENCESProbleme des kardiogenen SchocksShock following acute myocardial infarction current understanding of hemodynamic mechanismsHemodynamic measurements in a coronary care unitComparison of norepinephrine and isoproterenol in experimental coronary shockHämodynamische Veränderungen nach akutem MyokardinfarktThe treatment of shock complicating acute myocardial infarctionHemodynamic Studies in Cardiogenic ShockOn the definition and classification of shockHemodynamic effects of acute myocardial infarction in manThe Physiologic Basis for Treatment of Shock Associated with Myocardial InfarctionMyocardial Infarction with ShockEffect of changes in the coronary blood flow on the tone of the pulmonary vesselsShockHemodynamic Changes in Patients with AcuteThe Relation between the Location of Coronary Occlusions and the Occurrence of Shock in Acute Myocardial InfarctionSYSTEMIC SHOCK OF CARDIOPULMONARY ORIGINCIRCULATORY AND RESPIRATORY STUDIES IN MYOCARDIAL INFARCTION AND CARDIOGENIC SHOCKHaemodynamics in Acute Myocardial InfarctionHaemodynamics During Rest and Exercise at the end of Convalescence from Myocardial InfarctionShock in Acute Myocardial InfarctionAPPENDIXTherapy of cardiogenic shockProlonged cardiogenic shockCardiac output in acute myocardial infarctionUntersuchungen zur Pathophysiologie und Therapie des HerzinfarktesA clinical study of shock occurring during acute myocardial infarction an analysis of 58 casesSchock und KollapsDie Coronarerkrankungen. Coronarinsuffizienz, Angina pectoris und HerzinfarktWork capacity of the left ventricle following ligation of the coronary arteryEffect of systemic blood pressure and vasopressor drugs on coronary blood flow and the electrocardiogramHemodynamic studies in acute myocardial infarctionEstimation of the rates of uptake of Rb86 by the heart, liver and skeletal muscle of man with and without cardiac diseaseThe Treatment of Shock in Myocardial InfarctionThe mechanism and treatment of shock in acute myocardial infarctionCardiogenic shock 1 July 1955Volume 43, Issue 1Page: 100-119KeywordsAcute myocardial infarctionCardiac outputElectrocardiographyHealth statisticsHemodynamicsHospital medicinePrevention, policy, and public healthSurgeons ePublished: 1 December 2008 Issue Published: 1 July 1955 PDF downloadLoading ...