Reversible Rapidly Progressive Renal Failure with Nephrotic Syndrome Due to Fenoprofen Calcium
Authors: GREGORY A. CURT, ANTOINE KALDANY, LOYD G. WHITLEY, ANN W. CROSSON, ARTURO ROLLA, MANUEL J. MERINO, JOHN A. D'ELIA
Journal: Annals of Internal Medicine (1980)

Brief Reports1 January 1980Reversible Rapidly Progressive Renal Failure with Nephrotic Syndrome Due to Fenoprofen CalciumGREGORY A. CURT, M.D., ANTOINE KALDANY, M.D., LOYD G. WHITLEY, M.D., ANN W. CROSSON, M.D., ARTURO ROLLA, M.D., MANUEL J. MERINO, M.D., JOHN A. D'ELIA, M.D.GREGORY A. CURT, M.D.Search for more papers by this author, ANTOINE KALDANY, M.D.Search for more papers by this author, LOYD G. WHITLEY, M.D.Search for more papers by this author, ANN W. CROSSON, M.D.Search for more papers by this author, ARTURO ROLLA, M.D.Search for more papers by this author, MANUEL J. MERINO, M.D.Search for more papers by this author, JOHN A. D'ELIA, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-92-1-72 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptNonsteroidal antiinflammatory drugs have been reported to cause reversible acute renal failure (1-4). Unlike the so-called phenacetin-induced analgesic nephropathy (5), the nephrotoxicity of nonsteroidal antiinflammatory drugs may be secondary to their prostaglandin inhibitory effect (4). We report a case of acute renal failure with nephrotic syndrome due to a hypersensitivity reaction to fenoprofen calcium (Nalfon, Dista Products Company, Indianapolis, Indiana).A 50-year-old white woman with no history of renal or collagen-vascular disease was admitted on 5 May 1979 for treatment of morbid obesity. She had a history of severe osteoarthritis, sciatica, and surgical release of a left carpal tunnel. She...References1. 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Renal failure and interstitial nephritis due to penicillin and methicillin. N Engl J Med. 1968;279:1245-8. CrossrefMedlineGoogle Scholar9. VAN WYLEHOFFMAN JC. Periarteritis modosa: a fatal case of exfoliative dermatitis resulting from "Dilantin sodium" sensitization. Arch Intern Med. 1948;81:605-8. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: GREGORY A. CURT, M.D.; ANTOINE KALDANY, M.D.; LOYD G. WHITLEY, M.D.; ANN W. CROSSON, M.D.; ARTURO ROLLA, M.D.; MANUEL J. MERINO, M.D.; JOHN A. D'ELIA, M.D.Affiliations: Joslin Diabetes Foundation New England Deaconess Hospital Harvard Medical School Boston, Massachusetts PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAcute kidney injury complicating nephrotic syndrome of minimal change diseaseAcute Kidney Failure and Minimal Change DiseaseFenoprofen Calcium Dihydrate 53746-45-5Glomerular, tubular and interstitial nephritis associated with non‐steroidal antiinflammatory drugs. Evidence of a common mechanismNephrotoxicity associated with olsalazineNabumetone-Associated Interstitial NephritisSuspected Nafcillin-Induced Interstitial NephritisUrinary Excretion of Three Specific Renal Tubular Enzymes in Patients Treated with Nonsteroidal Anti-Inflammatory Drugs (NSAID)Drug-Induced Renal DisordersFPrediction of organ system toxicity with antirheumatic drug therapyReview: Acute tubulointerstitial nephritisAcute Interstitial Nephritis with Glomerulopathy Due to Nonsteroidal Anti-Inflammatory Agents: A Review of Its Clinical Spectrum and Effects of Steroid TherapyNonsteroidal anti-inflammatory drugs and coma: A case report of fenoprofen overdoseAnalgesic Nephropathy and the Effect of Non-Steroidal Anti-Inflammatory Drugs on the KidneyMinimal Change Glomerulopathy Associated With Nonsteroidal Antiinflammatory DrugsSouthwestern Internal Medicine Conference: Analgesic NephropathyPharmacologic Approaches to Musculoskeletal DisordersTreatmentArachidonic acid metabolism in renal diseaseNonsteroidal Antiinflammatory Drug-Induced Renal Dysfunction Related to Inhibition of Renal ProstaglandinsThe Nephrotic Syndrome and Its ComplicationsSuprofen-Related Nephrotoxicity A Distinct Clinical SyndromeDENISE HART, M.D., MICHAEL WARD, Pharm.D., MEYER D. 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LINTON, M.B., WILLIAM F. CLARK, M.D., ALBERT A. DRIEDGER, M.D., D. IAN TURNBULL, M.D., ROBERT M. LINDSAY, M.D.Toxic nephropathy from diagnostic and therapeutic agentsRenal Effects of FenoprofenS. PAUL HANDA, M.D. 1 January 1980Volume 92, Issue 1Page: 72-73KeywordsAcute renal failureAnalgesicsCalciumDrugsMedical servicesMorbid obesityOsteoarthritisProstaglandinRenal diseasesRenal failure ePublished: 1 December 2008 Issue Published: 1 January 1980 PDF downloadLoading ...