Organism Responsible for Nodular Cutaneous Microsporidiosis in a Patient with AIDS
Authors: Kent E. Kester
Journal: Annals of Internal Medicine (2000)

Letters5 December 2000Organism Responsible for Nodular Cutaneous Microsporidiosis in a Patient with AIDSKent E. Kester, MD, Govinda S. Visvesara, PhD, and Peter McEvoy, MDKent E. Kester, MDWalter Reed Army Institute of Research; Silver Spring, MD 20910 (Kester)Centers for Disease Control and Prevention; Atlanta, GA 30341-3724 (Visvesara)Armed Forces Institute of Pathology; Washington, DC 20307 (McEvoy)Search for more papers by this author, Govinda S. Visvesara, PhDWalter Reed Army Institute of Research; Silver Spring, MD 20910 (Kester)Centers for Disease Control and Prevention; Atlanta, GA 30341-3724 (Visvesara)Armed Forces Institute of Pathology; Washington, DC 20307 (McEvoy)Search for more papers by this author, and Peter McEvoy, MDWalter Reed Army Institute of Research; Silver Spring, MD 20910 (Kester)Centers for Disease Control and Prevention; Atlanta, GA 30341-3724 (Visvesara)Armed Forces Institute of Pathology; Washington, DC 20307 (McEvoy)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-133-11-200012050-00028 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:We recently reported an unusual case of disseminated microsporidiosis in a patient with late-stage HIV infection (1). At the time of our report, we could not definitively identify the microsporidian involved, although the structural details seen on electron microscopy suggested that it was an Encephalitozoon-like species. We now report definitive identification of the organism.The identification was performed by using an indirect immunofluorescence assay, which has been previously used to identify microsporidia in stool samples (2). Briefly, slides containing unstained skin biopsy material were deparaffinized and then assayed by using primary rabbit antisera raised against Encephalitozoon cuniculi, ...References1. Kester KE, Turiansky GW, McEvoy PL. Nodular cutaneous microsporidiosis in a patient with AIDS and successful treatment with long-term oral clindamycin therapy. Ann Intern Med. 1998;128:911-4. LinkGoogle Scholar2. Moura H, Sodre FC, Bornay-Llinares FJ, Leitch GJ, Navin T, Wahlquist S, et al . Detection by an immunofluorescence test of Encephalitozoon intestinalis spores in routinely formalin-fixed stool samples stored at room temperature. J Clin Microbiol. 1999;37:2317-22. CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Walter Reed Army Institute of Research; Silver Spring, MD 20910 (Kester)Centers for Disease Control and Prevention; Atlanta, GA 30341-3724 (Visvesara)Armed Forces Institute of Pathology; Washington, DC 20307 (McEvoy) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byMicrosporidiosis in HumansCutaneous microsporidiosis in an immunosuppressed patientTherapeutic targets for the treatment of microsporidiosis in humansMicrosporidiosis in HumansMicrosporidiosisExtraintestinal MicrosporidiosisClinical Syndromes Associated with MicrosporidiosisLaboratory Diagnosis of MicrosporidiaMicrosporidiasisDisseminated Microsporidiosis in an Immunosuppressed PatientMicrosporidiosisLincomycin and ClindamycinMicrosporidiosisParasitic infections of the intestine 5 December 2000Volume 133, Issue 11Page: 925KeywordsAIDSAntibioticsBiopsyElectron microscopyHIV infectionsImmunofluorescenceMicrosporidiaMicrosporidiosisMonoclonal antibodiesRabbits ePublished: 5 December 2000 Issue Published: 5 December 2000 Copyright & PermissionsCopyright © 2000 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...