NORTH AMERICAN BLASTOMYCOSIS: A CLINICAL STUDY OF 40 CASES
Authors: E I CHERNISS, B A WAISBREN
Journal: Annals of Internal Medicine (1956)

Article1 January 1956NORTH AMERICAN BLASTOMYCOSIS: A CLINICAL STUDY OF 40 CASESEDWARD I. CHERNISS, M.D., BURTON A. WAISBREN, M.S., M.D.EDWARD I. CHERNISS, M.D.Search for more papers by this author, BURTON A. WAISBREN, M.S., M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-44-1-105 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptINTRODUCTIONNorth American blastomycosis is recognized as a chronic granulomatous infection caused by the hyphomycete,Blastomyces dermatitidis. It appears in man both as a relatively benign dermatologic infection and as a malignant, widely disseminated systemic disease that has predilection for lungs, bones and subcutaneous tissue. The cutaneous form has been successfully treated with iodides, radiation and excision.1The systemic form has been notoriously resistant to therapy and associated with a high mortality.2Both types have been characterized by chronicity and periods of indolence and exacerbation, with recurrence after prolonged periods of clinical inactivity or cure.2, 3Fulminant, rapidly fatal pulmonary...Bibliography1. ConantSmithBakerCallawayMartin NTDTRDJLDS: Manual of clinical mycology, 2nd Ed., 1954, W. B. Saunders Co., Philadelphia. CrossrefGoogle Scholar2. MartinSmith DSDT: Blastomycosis (American blastomycosis, Gilchrist's disease). I. A review of the literature. II. A report of 13 new cases, Am. Rev. Tuberc. 39: 275, 488, 1939. Google Scholar3. DowningFolan JGDW: An unusual case of cutaneous blastomycosis, New England J. Med. 252: 103, 1955. CrossrefMedlineGoogle Scholar4. BakerWarrickNoojin RDGWRQ: Blastomycotic pneumonia, a report of a fatal case of 22 days' duration, Arch. Int. 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TaberViningWaksman WALCSA: Candidin, a new antifungal antibiotic produced by Streptomyces viridoflavus , Antibiotics and Chemotherapy 4: 455, 1954. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Milwaukee, Wisconsin*Received for publication June 17, 1955.From the Infectious Disease Control Unit of the Department of Medicine of the Milwaukee County General Hospital and Marquette University School of Medicine. 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