THE RESULTS OF 2-HYDROXYSTILBAMIDINE THERAPY IN DISSEMINATED COCCIDIOIDOMYCOSIS
Authors: I SNAPPER, L A BAKER, B D EDIDIN, D S KUSHNER
Journal: Annals of Internal Medicine (1955)

Article1 August 1955THE RESULTS OF 2-HYDROXYSTILBAMIDINE THERAPY IN DISSEMINATED COCCIDIOIDOMYCOSISI. SNAPPER, M.D., F.A.C.P., LYLE A. BAKER, M.D., F.A.C.P., BERNARD D. EDIDIN, M.D., DANIEL S. KUSHNER, M.D.I. SNAPPER, M.D., F.A.C.P.Search for more papers by this author, LYLE A. BAKER, M.D., F.A.C.P.Search for more papers by this author, BERNARD D. EDIDIN, M.D.Search for more papers by this author, DANIEL S. KUSHNER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-43-2-271 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe treatment of disseminated coccidioidomycosis has been unsatisfactory. In its progressive or meningitic form the disease has been uniformly fatal, although some cases have lingered on for a long time. In recent years an increasing number of reports have appeared dealing with the promising results of treatment of certain disseminated mycotic infections with stilbamidine. Arrest of blastomycosis by stilbamidine therapy can now be accepted.5, 6, 7, 14, 15, 16, 19, 23, 25, 26 Successful treatment of actinomycosis has been reported.12 The efficacy of the drug in the treatment of other mycotic diseases, however, seems doubtful.13, 14In vitro studies with...Bibliography1. AraiSnapper HI: The influence of stilbamidine upon kidney function, liver function, and peripheral blood in multiple myeloma: neurologic sequelae of stilbamidine therapy, New York State J. Med. 47: 1867, 1947. MedlineGoogle Scholar2. BennettMilderBaker HDJWLA: Coccidioidomycosis—possible fomite transmission, J. Lab. and Clin. Med. 43: 633, 1954. MedlineGoogle Scholar3. CohenBos RJ: Two new fungicides for Coccidioides immitis , Arch. Pediat. 69: 33, 1952. MedlineGoogle Scholar4. 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Author, Article, and Disclosure InformationAffiliations: *Received for publication November 29, 1954.From the Departments of Medicine of the Veterans Administration Hospital, Hines, Illinois, and of the Cook County Hospital, and the Hektoen Institute for Medical Research, Chicago, Illinois. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byTHE AROMATIC DIAMIDINESDie CoccidioidomykoseDie CoccidioidomykoseDie AntimykoticaTHE TOXICITY OF 2-HYDROXYSTILBAMIDINE: PROBABLE FATAL TOXIC REACTION DURING TREATMENT OF BLASTOMYCOSIS*J. WILLIAM OBERMAN, M.D., ENID F. GILBERT, M.D.Aminostilbamidine—A Fungistatic Agent 1 August 1955Volume 43, Issue 2Page: 271-286KeywordsBlastomycosisCoccidioidomycosisHealth services researchHospital medicineLesionsMedical servicesMeningitisNauseaPrevention, policy, and public healthResearch grants ePublished: 1 December 2008 Issue Published: 1 August 1955 PDF downloadLoading ...