FATAL POLYCYTHEMIA FOLLOWING PERNICIOUS ANEMIA TREATED WITH VITAMIN B_12
Authors: C F HINZ
Journal: Annals of Internal Medicine (1957)

Case Reports1 September 1957FATAL POLYCYTHEMIA FOLLOWING PERNICIOUS ANEMIA TREATED WITH VITAMIN B12CARL F. HINZ JR., M.D.CARL F. HINZ JR., M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-47-3-544 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptINTRODUCTIONSince the introduction of specific therapy for pernicious anemia, persons with this disease have lived sufficiently long to develop other disorders of the hematopoietic system. A striking but distinctly unusual instance of this has been the development in such patients of polycythemia vera. Such cases would appear to be interesting in light of the frequent speculation concerning the etiology and pathogenesis of pernicious anemia and polycythemia rubra vera.A review of the literature reveals several instances of polycythemia developing in association with liver therapy, and a few cases of typical polycythemia vera associated with or following treatment for classic...Bibliography1. AdamsonStorey WBJE: Excess intrinsic factor in polycythemia rubra vera, Texas M. J. 36: 26, 1940. Google Scholar2. Avery H: Pernicious anemia following erythremia, Lancet 1: 342, 1930. CrossrefGoogle Scholar3. BarnardKopetStahl RDSJAE: Erythremia during massive oral streptomyces derived B12 therapy, Ann. Allergy 9: 360, 1951. MedlineGoogle Scholar4. BauerSchwarz JE: Ein Fall myeloischer Leukämie mit Splenectomie und nachfolgenden Polycythämie, Wien. klin. Wchnschr. 44: 655, 1931. Google Scholar5. Birnie GA: Alternating pernicious anemia and polycythemia, M. J. Australia 2: 498, 1936. 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LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Cleveland, Ohio*Received for publication March 21, 1956.From the Department of Surgery, Cleveland City Hospital, and the School of Medicine, Western Reserve University.Requests for reprints should be addressed to Carl F. Hinz, Jr., M.D., Western Reserve University School of Medicine, Cleveland 6, Ohio. 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KLIPSTEIN, M.D.Coincidental Myxoedema and Pernicious Anaemia with Subsequent Development of Polycythaemia after Vitamin B12 TherapyVERONICA HALMOS, M.D., F.R.C.P.(C), ROBERT VOLPÉ, M.D., F.R.C.P.(C)Pernicious Anemia and Polycythemia VeraGastric pepsin secretion and ABO blood groups in polycythemia vera 1 September 1957Volume 47, Issue 3Page: 544-552KeywordsAnemiaHospital medicineMegaloblastic anemiaNecrosisPathogenesisPernicious anemiaPolycythemiaPolycythemia veraSurgeryThrombosis ePublished: 1 December 2008 Issue Published: 1 September 1957 PDF downloadLoading ...