THE METABOLIC EFFECTS OF HUMAN AND MONKEY GROWTH HORMONE IN MAN
Authors: J C BECK, E E McGARRY, I DYRENFURTH, E H VENNING
Journal: Annals of Internal Medicine (1958)

Article1 November 1958THE METABOLIC EFFECTS OF HUMAN AND MONKEY GROWTH HORMONE IN MANJOHN C. BECK, M.D., E. E. MCGARRY, M.D., I. DYRENFURTH, Ph.D., E. H. VENNING, Ph.D.JOHN C. BECK, M.D.Search for more papers by this author, E. E. MCGARRY, M.D.Search for more papers by this author, I. DYRENFURTH, Ph.D.Search for more papers by this author, E. H. VENNING, Ph.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-49-5-1090 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptINTRODUCTIONThe biochemical nature and diverse physiologic effects of pituitary growth hormone have been reviewed recently by a number of investigators in an international symposium,1by Astwood,2Randle,3Ketterer et al.,4Li5and Hays and Steelman.6A recent development has been the observations which suggest a degree of specificity among growth hormones obtained from different species. Normal and hypophysectomized guinea pigs fail to respond to bovine growth hormone,7fish growth hormone is inactive in the rat,8while fish and bovine growth hormones are active in intact and hypophysectomized fish.9-12Knobil13-17demonstrated that both intact and hypophysectomized monkeys fail to respond...Bibliography1. 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Author, Article, and Disclosure InformationAffiliations: Montreal,*Presented at the Thirty-ninth Annual Session of The American College of Physicians, Atlantic City, New Jersey, May 2, 1958.From The McGill University Clinic, Royal Victoria Hospital, Montreal, Quebec, Canada.†This work was supported in part by a grant from the National Research Council (Canada); The Research and Development Division, Office of the Surgeon General, Department of the Army, Washington, D. C., under Contract No. DA-49-007-MD-532; and the Department of Health, Education, and Welfare, National Heart Institute, Grant No. H-2716, Bethesda, Maryland.Requests for reprints should be addressed to John C. Beck, M.D., Royal Victoria Hospital, Montreal 2, Canada. 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