ROENTGENOLOGIC AND CLINICAL ASPECTS OF MULTIPLE MYELOMA WITH REPORT OF AN UNUSUAL CASE
Authors: O DEUTSCHBERGER, H FUJIY
Journal: Annals of Internal Medicine (1959)

Case Reports1 May 1959ROENTGENOLOGIC AND CLINICAL ASPECTS OF MULTIPLE MYELOMA WITH REPORT OF AN UNUSUAL CASEOTTO DEUTSCHBERGER, HERLEY FUJIYOTTO DEUTSCHBERGERSearch for more papers by this author, HERLEY FUJIYSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-50-5-1309 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptMultiple myeloma was first described as an entity in 1889 by Kahler, who stated that the following features are characteristic of this disease:1. Bone pain and abnormal fragility.2. Anemia, weakness and loss of weight.3. Presence of Bence Jones proteins in the urine.The original description of multiple myeloma refers to diffusely infiltrating, intramedullary, multiple tumors which consist of myeloma cells. These cells could best be described as plasmoid cells, since they have the characteristics of young plasma cells. The tumors, frequently referred to as plasmacytomas, are found mainly in the flat bones.Today, we know that multiple...Bibliography1. Kinney LC: Multiple myeloma, Radiology 35: 667, 1940. CrossrefGoogle Scholar2. LichtensteinJaffe LLHL: Multiple myeloma (a summary based on 35 cases, 18 of which came to autopsy), Arch. Path. 44: 207, 1947. Google Scholar3. HeiserSchwartzman SJ: Variations in roentgen appearance of the skeletal system of myeloma, Radiology 58: 178, 1952. CrossrefMedlineGoogle Scholar4. AdamsAllingLawrence WSELJS: Multiple myeloma, Am. J. Med. 6: 141, 1949. CrossrefMedlineGoogle Scholar5. SnapperTurnerMoscovitz ILBHL: Multiple myeloma, 1953, Grune & Stratton, Inc., New York. Google Scholar6. Wintrobe MM: Clinical hematology, 1944, Lea & Febiger, Philadelphia. Google Scholar7. Wintrobe MM: Hyperproteinemia associated with multiple myeloma, Bull. Johns Hopkins Hosp. 52: 156, 1933. Google Scholar8. Meacham GC: Plasma cell myeloma, Ann. Int. Med. 38: 1035, 1953. LinkGoogle Scholar9. BrichtenbucherHertzog RBAJ: Multiple myeloma (a review of 95 proven cases with 75 autopsies), Minnesota Med. 32: 986, 1949. MedlineGoogle Scholar10. KestersonMcSwain JB: Myeloma of bone, J. Bone and Joint Surg. 34A: 224, 1952. CrossrefGoogle Scholar11. GeschickterCopeland CFMM: Multiple myeloma, Arch. Surg. 16: 807, 1928. CrossrefGoogle Scholar12. GeschickterCopeland CFMM: Tumors of bone, 1936, American Journal of Cancer, New York. Google Scholar13. GhormleyPollackHallBeizer RKGABELH: Multiple myeloma, Surg., Gynec. and Obst. 74: 242, 1942. Google Scholar14. Slavens JJ: Multiple myeloma in a child, Am. J. Dis. Child. 47: 821, 1934. Google Scholar15. Rubinstein MA: Multiple myeloma in a 15 year old boy, New York State J. Med. 44: 2491, 1944. Google Scholar16. AegertuRobbins ER: The changing concept of myeloma of bone, Am. J. M. Sc. 213: 282, 1947. CrossrefMedlineGoogle Scholar17. WoodQuinlanMerill HJWEF: Multiple myeloma in a youth, Am. J. Roentgenol. 32: 167, 1947. Google Scholar18. BayrdHeck EDFJ: Multiple myeloma (a case review of 83 proved cases), J. A. M. A. 147: 156, 1947. Google Scholar19. Limarzi LR: Diagnoses and therapeutic aspects of multiple myeloma, M. Clin. North America 35: 189 (Jan.) 1951. CrossrefMedlineGoogle Scholar20. Atkinson FR: Multiple myeloma, M. Press 195: 312, 1937. Google Scholar21. Magnus-Levy A: Multiple myeloma, Ztschr. f. klin. Med. 126: 62, 1933. Google Scholar22. Butts M: Multiple myeloma (review of 40 cases), 1940 Year Book of Radiology. Google Scholar23. GutmanMooreGutmanMcClellanKabat ABDHEBVEA: Fractionation of serum protein in hyperproteinemia with special reference to multiple myeloma, J. Clin. Investigation 20: 765, 1941. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Received for publication August 27, 1958.From the X-ray Department of Bird S. Coler Hospital, New York Medical College, and the Metropolitan Medical Center Research Unit.Requests for reprints should be addressed to Otto Deutschberger, M.D., 27 West Eighty-sixth Street, New York 24, N. Y. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 May 1959Volume 50, Issue 5Page: 1309-1320KeywordsAnemiaBoneCellsLesionsMultiple myelomaMyelomaOsteoporosisProteinsUrineWeight loss ePublished: 1 December 2008 Issue Published: 1 May 1959 PDF downloadLoading ...