THE USE OF HISTIDINE HYDROCHLORIDE (LAROSTIDIN) IN THE TREATMENT OF PEPTIC ULCER
Authors: John T. Eads
Journal: Annals of Internal Medicine (1936)

Article1 November 1936THE USE OF HISTIDINE HYDROCHLORIDE (LAROSTIDIN) IN THE TREATMENT OF PEPTIC ULCERJOHN T. EADS, M.D.JOHN T. EADS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-10-5-639 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptDuring the past three years a great deal of interest has been aroused by reports of the use of histidine hydrochloride (Larostidin) in the treatment of peptic ulcer. Due for the most part to favorable immediate results reported, this particular substance has enjoyed a widespread usage. In very few of the reports has there been a sufficient follow-period of observation for really accurate estimation of its true worth in comparison with the time honored dietary and alkaline régime. It has been the hope of the users of this treatment that the long drawn-out medical treatment of peptic ulcers could be...References1. WEISSARON AGE: Traitement des ulcères gastro-duodénaux chez l'homme par les injections d'acides aminés (tryptophane histidine), Compt. rend. Soc. de biol., 1933, cxii, 1530-1531. Google Scholar2. MANNWILLIAMSON FCCS: The experimental production of peptic ulcer, Ann. Surg., 1923, lxxvii, 409-423. CrossrefGoogle Scholar3. WEISSARON AGE: Orientation nouvelle du probleme de l'ulcère experimentale: Le rôle de certaines acides amines dans la pathogènie de l'ulcère et dans sa therapeutique, Bull. et mém. Soc. nat. de chir., 1933, lix, 898-901. Google Scholar4. WEISSARON AGE: Rôle des acides amines dans l'évolution de l'ulcère experimentale; influence de l'histidine, Presse méd., 1933, xli, 1880-1883. Google Scholar5. ARON E: Récherches sur l'ulcère experimental et sur le rôle des acides amines dans son evolution, Strasbourg med., 1933, xciii, 731, 769. Google Scholar6. LENORMAND J: Acidotherapie aminee et epigastralgies de cause non ulcèreuse (action de l'histidine), Gaz. d. hôp., 1934, cvii, 255. Google Scholar7. BOGENDORFER L: Treatment of gastric ulcer with histidine preparation, München. med. Wchnschr., 1934, lxxxi, 1270. Google Scholar8. HESSEL G: Die Behandlung des Magen- und Zwölffingerdarmgeschwürs mit Histidin, München. med. Wchnschr., 1934, lxxxi, 1890-1891. Google Scholar9. BULMER E: Histidine treatment of peptic ulcer, with a note on 52 cases, Lancet, 1934, ii, 1276-1278. CrossrefGoogle Scholar10. STOLZWEISS AAG: Le traitement de l'ulcus gastroduodenal par l'histidine; resultats de deux annees d'expèrience clinique, Presse méd., 1935, xliii, 864. Google Scholar11. BLUM P: Orientation nouvelle de la pathogènie de l'ulcére experimental gastrique et de la therapeutique de l'ulcère humain, Bull. gen. de therap., 1933, clxxxiv, 253-260. Google Scholar12. WEISS AG: Les ulceres experimentaux, Praxis 9, No. 21, 1934. Google Scholar13. VOLINIMCLAUGHLIN IRF: The histidine monohydrochloride therapy of gastroduodenal ulcer: preliminary report, Med. Rec., 1935, cxli, 364. Google Scholar14. EADS JT: Histidine in the treatment of peptic ulcer: a preliminary report, Am. Jr. Digest. Dis. and Nutr., 1935, ii, 426. CrossrefGoogle Scholar15. RAFSKY HA: Injection treatment of peptic ulcer with special reference to the use of histidine monohydrochloride, Med. Rec., 1935, cxlii, 289. Google Scholar16. VOLINIMCLAUGHLIN IFRF: The histidine monohydrochloride therapy of gastro-duodenal ulcer, Ill. Med. Jr., 1936, lxix, 39-45. Google Scholar17. SANDWEISS DJ: Treatment of gastroduodenal ulcer with histidine monohydrochloride (Larostidin), Jr. Am. Med. Assoc., 1936, cvi, 1452-1459. CrossrefGoogle Scholar18. MARTIN KA: Histidine hydrochloride versus diet and alkalis in treatment of peptic ulcer: the immediate and late effects in 41 cases, Jr. Am. Med. Assoc., 1936, cvi, 1468- 1473. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Philadelphia, Pennsylvania*Received for publication June 9, 1936.From the Medical Department, Jefferson Hospital, Philadelphia. The preparation of Histidine solution used in this series of treatments is Larostidin supplied by Hoffmann-La-Roche, Inc., Nutley, N. J. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 November 1936Volume 10, Issue 5Page: 639-644KeywordsPeptic ulcers ePublished: 1 December 2008 Issue Published: 1 November 1936 PDF downloadLoading ...