ACID-BASE WATER BALANCE
Authors: Edward C. Mason, Arthur A. Hellbaum
Journal: Annals of Internal Medicine (1938)

Article1 June 1938ACID-BASE WATER BALANCEEDWARD C. MASON, M.D., PH.D., F.A.C.P., ARTHUR A. HELLBAUM, M.A., PH.D.EDWARD C. MASON, M.D., PH.D., F.A.C.P.Search for more papers by this author, ARTHUR A. HELLBAUM, M.A., PH.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-11-12-2206 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptUnder certain abnormal conditions, the body tissues hold an abnormally large amount of water (edema), and this increased hydration of the tissues most frequently accompanies impairment of the blood circulation. One of the functions of the blood is to carry waste products (solid, liquid, and gas) rom the tissues; the most obvious of these is the transport of carbon dioxide. If carbon dioxide is allowed to accumulate in the presence of water, the result is the formation of carbonic acid. Studies conducted on excised organs and other colloids have revealed the fact that acid produces a marked increase in their...Bibliography1. FISCHER MH: Oedema and nephritis, 1915, John Wiley and Sons, Inc., New York. Google Scholar2. Ibid., page 194. Google Scholar3. LEATHES JB: Renal efficiency tests in nephritis and the reaction of the urine, British Med. Jr., 1919, ii, 165-167. CrossrefGoogle Scholar4. COLLIPBACKUS JBPL: The effect of prolonged hyperpnea on the carbon dioxide combining power of the plasma, the carbon dioxide tension of alveolar air and the excretion of acid and basic phosphate and ammonia by the kidney, Am. Jr. Physiol., 1920, li, 568-579. CrossrefGoogle Scholar5. MEYERCOHN LFS: Klinische Beobachtungen und Stoffwechsel Versuche über die Wirkung verschiedener Salze beim Säugling, Ztschr. f. Kinderheilk., 1911, ii, 360-419. CrossrefGoogle Scholar6. SCHULTZ E: Klinische Beobachtungen über Nierenentzündung bei Kriegsteilnehmern, Ztschr. f. klin. Med., 1918, lxxxvi, 111-138. Google Scholar7. HÜLSE W: Über den Einfluss der Kalksalze auf Hydrops und Nephritis, Zentralbl. f. inn. Med., 1920, xli, 441-454. Google Scholar8. ROCKWOODBARRIER RCW: Calcium treatment for edema, Arch. Int. Med., 1924, xxxiii, 643-657. CrossrefGoogle Scholar9. KEITHBARRIERWHELAN NMCWM: Treatment of nephritis and edema with calcium, Jr. Am. Med. Assoc., 1924, lxxxiii, 667-670. Google Scholar10. HALDANE JB: Experiments on the regulation of the blood's alkalinity, II, Jr. Physiol., 1921, lv, 265-275. CrossrefGoogle Scholar11. KEITHBARRIERWHELAN NMCWM: The diuretic action of ammonium chlorid and novasurol, Jr. Am. Med. Assoc., 1925, lxxxv, 799-806. CrossrefGoogle Scholar12. GAMBLEBLACKFANHAMILTON JLKDB: A study of the diuretic action of acid producing salts, Jr. Clin. Invest., 1925, i, 359. CrossrefGoogle Scholar13. HENDERSONHAGGARD YHW: Respiratory regulation of the CO2 capacity of the blood, Jr. Biol. Chem., 1918, xxxiii, 333-371. CrossrefGoogle Scholar14. LOEB J: Amphoteric colloids. II. Volumetric analysis of ion-protein compounds; the significance of the iso-electric point for the purification of amphoteric colloids, Jr. Gen. Physiol., 1918, i, 237-254. CrossrefGoogle Scholar15. HAGGARDHENDERSON HWY: Hemato-respiratory functions, VII, Jr. Biol. Chem., 1920-21, xlv. Google Scholar16. VAN SLYKE DD: Carbon dioxide carriers of blood, Physiol. Rev., 1921, i, 141. CrossrefGoogle Scholar17. ROUGHTON FJ: Recent work on carbon dioxide transport by blood, Physiol. Rev., 1935, xv, 241-296. CrossrefGoogle Scholar18. LASHMET FH: The treatment of nephritic edema by acid, Jr. Am. Med. Assoc., 1931, xcvii, 918-919. CrossrefGoogle Scholar19. BERGERBINGER EHMW: The status of the kidneys in alkalosis, Jr. Am. Med. Assoc., 1935, civ, 1383. CrossrefGoogle Scholar20. STEELE JM: Renal insufficiency developing during prolonged use of alkalies: report of a case, Jr. Am. Med. Assoc., 1936, cvi, 2049. CrossrefGoogle Scholar21. ZIEGLERBRICE EEAT: Reaction and specific gravity of the urine in relation to nephritis (a study of ten thousand urinalyses), ANN. INT. MED., 1937, ii, 768-776. Google Scholar22. NOTH PH: Pick's disease: A record of eight years' treatment with salyrgan, ammonium nitrate, and abdominal paracentesis, Proc. Staff Meet. Mayo Clinic, August 18, 1937. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Oklahoma City, Oklahoma*Read before the American Physiological Society, Baltimore, Maryland, April 2, 1938.From the Department of Physiology, University of Oklahoma, School of Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byTheory and therapy of shock 1 June 1938Volume 11, Issue 12Page: 2206-2213KeywordsBicarbonatesBloodCarbon dioxideEdema ePublished: 1 December 2008 Issue Published: 1 June 1938 PDF downloadLoading ...