THE HIPPURIC ACID TEST IN HYPERTHYROIDISM
Authors: Samuel F. Haines, Thomas B. Magath, Marschelle H. Power
Journal: Annals of Internal Medicine (1941)

Article1 January 1941THE HIPPURIC ACID TEST IN HYPERTHYROIDISMSAMUEL F. HAINES, M.D., F.A.C.P., THOMAS B. MAGATH, M.D., F.A.C.P., MARSCHELLE H. POWER, Ph.D.SAMUEL F. HAINES, M.D., F.A.C.P.Search for more papers by this author, THOMAS B. MAGATH, M.D., F.A.C.P.Search for more papers by this author, MARSCHELLE H. POWER, Ph.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-14-7-1225 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptFor many years it has been known that disturbances in the function of the liver might occur in severe exophthalmic goiter. Jaundice has been recognized to be a serious, and usually late, development in the crisis of exophthalmic goiter.In cases of this type livers have frequently showed changes designated by Robertson1as "subacute yellow atrophy." In 1933, Weller2found a patchy, chronic parenchymatous, interlobar hepatitis in many of the livers of patients with exophthalmic goiter. In the same year, Beaver and Pemberton3studied the livers of 107 patients with exophthalmic goiter and found acute degenerative lesions, simple atrophy, or...References1. ROBERTSON HE: Personal communication to the authors. Google Scholar2. WELLER CV: Hepatic pathology in exophthalmic goiter, ANN. INT. MED., 1933, vii, 543-560. Google Scholar3. BEAVERPEMBERTON DCJD: The pathologic anatomy of the liver in exophthalmic goiter, ANN. INT. MED., 1933, vii, 687-708. Google Scholar4. KURIYAMA S: The influence of thyroid feeding upon carbohydrate metabolism: I. The storage and mobilization of the liver glycogen in thyroid-fed animals, Jr. Biol. Chem., 1918, xxxiii, 193-205. CrossrefGoogle Scholar5. SANGERHUN BJEG: The glucose mobilization rate in hyperthyroidism, Arch. Int. Med., 1922, xxx, 397-406. CrossrefGoogle Scholar6. YOUMANSWARFIELD JBLM: Liver injury in thyrotoxicosis evidenced by decreased functional efficiency, Arch. Int. Med., 1926, xxxvii, 1-17. CrossrefGoogle Scholar7. BARTELS EC: Liver function in hyperthyroidism as determined by the hippuric acid test, ANN. INT. MED., 1938, xii, 652-674. Google Scholar8. QUICK AJ: The synthesis of hippuric acid; a new test of liver function, Am. Jr. Med. Sci., 1933, clxxxv, 630-635. CrossrefGoogle Scholar9. QUICK AJ: Personal communication to the authors. Google Scholar10. GRIFFITH WH: Benzoylated amino acids in the animal organism. III. A method for the determination of hippuric acid and a study of the synthesis of hippuric acid in rabbits, Jr. Biol. Chem., 1926, lxix, 197-208. CrossrefGoogle Scholar11. SNELLPLUNKETT AMJE: The hippuric acid test for hepatic function; its relation to other tests in general use, Am. Jr. Digest. Dis. and Nutr., 1936, ii, 716-721. Google Scholar12. WEGELIN C: On the antagonism between thyroxine and vitamin A, West Jr. Surg., Obst. and Gynec., 1939, xlvii, 147-154. Google Scholar13. HIMWICHGOLDFARBCOWGILL HEWGR: Studies in the physiology of vitamins. XVII. The effect of thyroid administration upon the anorexia characteristic of lack of undifferentiated vitamin B, Am. Jr. Physiol., 1932, xcix, 689-695. CrossrefGoogle Scholar14. PLUMMER HS: The clinical and pathological relationship of simple and exophthalmic goiter, Am. Jr. Med. Sci., 1913, cxlvi, 790-795. CrossrefGoogle Scholar15. BOYCE FF: Hepatic and biliary tract disease; a review of recent significant advances, Ann. Surg., 1939, cix, 351-372. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Rochester, Minnesota*Submitted for publication August 11, 1939. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byBIOCHEMICAL ABNORMALITIES IN THYROID DISEASEThe effect of altered thyroid function on the ultrastructure of the human liverPhysiologische Chemie einzelner Lebensvorgänge und Organe (Fortsetzung)Krankheiten der SchilddrüseGalactose Tolerance in Jaundice and Hyperthyroidism 1 January 1941Volume 14, Issue 7Page: 1225-1232KeywordsAtrophyChronic hepatitisHepatitis AHyperthyroidismLesionsLiver ePublished: 1 December 2008 Issue Published: 1 January 1941 PDF downloadLoading ...