THE USE OF SULFANILAMIDE IN PULMONARY TUBERCULOSIS; PRELIMINARY REPORT
Authors: Ellis B. Freilich, George C. Coe, Norman A. Wien
Journal: Annals of Internal Medicine (1939)

Article1 December 1939THE USE OF SULFANILAMIDE IN PULMONARY TUBERCULOSIS; PRELIMINARY REPORTELLIS B. FREILICH, M.D., GEORGE C. COE, M.D., NORMAN A. WIEN, M.D.ELLIS B. FREILICH, M.D., GEORGE C. COE, M.D., NORMAN A. WIEN, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-13-6-1042 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe chemotherapeutic effects of sulfanilamide (para-amino-benzene sulfonamide) in certain infectious diseases have been successfully demonstrated in humans and in experimental animals. Although the best results have been obtained in beta hemolytic streptococcic infections, it has been used in other conditions, as gonococcic urethritis, meningococcus meningitis, colon bacillus pyelitis, brucellosis, etc., with varying degrees of success. Intensive studies have been carried out by Long and Bliss, who in a recent article1 give an excellent bibliography of investigations in this field.However, the possible use of sulfanilamide in chronic granulomatous infections has so far received little if any attention. In January 1938...Bibliography1. LONGBLISS PHEA: Clinical use of sulfanilamide and its derivatives in the treatment of infectious diseases, ANN. INT. MED., 1937, xi, 575. Google Scholar2. RICHFOLLIS ARRH: Inhibitory effect of sulfanilamide on the development of experimental tuberculosis in the guinea pig, Bull. Johns Hopkins Hosp., 1938, lxii, 77. Google Scholar3. DIETRICH HF: Prontosil in experimental tuberculosis, Am. Rev. Tuberc., 1938, xxxviii, 388. Google Scholar4. BLISSLONG EAPH: Observations on the mode of action of sulfanilamide, Jr. Am. Med. Assoc., 1937, cix, 1524. CrossrefGoogle Scholar5. OSGOODBROWNLEE EEIE: Culture of human marrow: Studies on the mode of action of sulfanilamide, Jr. Am. Med. Assoc., 1938, cx, 349. CrossrefGoogle Scholar SMITHBURN KC: Inefficiency of prontylin in experimental tuberculosis, Proc. Soc. Exper. Biol. and Med., 1938, xxxviii, 574-575. CrossrefGoogle Scholar GREEYCAMPBELLCOLLY PHHHAW: Effect of sulfanilamide on experimental tuberculosis in the guinea pig, Proc. Soc. Exper. Biol. and Med., 1938, xxxix, 22-24. CrossrefGoogle Scholar BUTTLEPARISH GAHJ: Treatment of tuberculosis in guinea pigs with sulfanilamide, Brit. Med. Jr., 1938, ii, 776-777. CrossrefGoogle Scholar GREEYBODDINGTONLITTLE PHGDMH: Sulfanilamide and related compounds in experimental tuberculosis, Proc. Soc. Exper. Biol. and Med., 1939, xl, 418-420. CrossrefGoogle Scholar FANIELJEURISSENCOURTOISDWELSHAUVERS HARF: Sulfanilamide and tuberculosis, Bruxelles-méd., 1939, xix, 725. Google Scholar CLIMENKOSCHMIDT DRRL: N′-Dodecanoylsulfanilamide. II. Experimental infections with beta hemolytic streptococci and human tubercle bacilli, Pathological Laboratory, Calco Chemical Co., Cold Spring Harbor, May, 1939. (Personal communication.) Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Chicago, Illinois*Received for publication November 7, 1938.From the Tuberculosis Division, Cook County Hospital, Chicago. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySulfonamide derivatives as Mycobacterium tuberculosis inhibitors: in silico approachSynthesis of 2,4-Diaminopyrimidine Core-Based Derivatives and Biological Evaluation of Their Anti-Tubercular ActivitiesTargeting intracellular p-aminobenzoic acid production potentiates the anti-tubercular action of antifolatesThe potential role of trimethoprim-sulfamethoxazole in the treatment of drug-resistant tuberculosisMycobacterium tuberculosis Folate Metabolism and the Mechanistic Basis for para -Aminosalicylic Acid Susceptibility and ResistanceIs repositioning of drugs a viable alternative in the treatment of tuberculosis?Tuberculosis and Trimethoprim-Sulfamethoxazole 1 December 1939Volume 13, Issue 6Page: 1042-1045KeywordsBacillusBrucellosisColonInfectious diseasesMeningitisMeningococcal diseaseNeisseria meningitidisStreptococcal infectionsSulfonamide ePublished: 1 December 2008 Issue Published: 1 December 1939 PDF downloadLoading ...