NONPUERPERAL LACTATION: A Review with Case Reports
Authors: A E WHITE
Journal: Annals of Internal Medicine (1960)

Article1 June 1960NONPUERPERAL LACTATION: A Review with Case ReportsALBERT E. WHITE, M.D.ALBERT E. WHITE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-52-6-1264 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptClassification of patients with nonpuerperal lactation (Latin, lactis, milk) or galactorrhea (Greek, galakto, milk) is frequently difficult, especially with the eponymic inconsistencies found in the current medical literature. A review of this material, together with characterization and comparison of the various syndromes is presented.PUERPERAL LACTATIONDuring pregnancy, the increasing amounts of circulating estrogen and progesterone, together with adrenal corticoids and growth hormone, cause maturation of breast gland and duct tissue.4, 22, 33High levels of estrogen and progesterone during pregnancy inhibit the release of prolactin (mammogen, lactogen, lactogenic hormone) from the eosinophilic cells of the anterior pituitary. Immediately post...Bibliography1. Ahumadadel Castillo JCEB: Sobre un caso de galactorrea y amenorrea, Bol. Soc. de obst. y ginec. de Buenos Aires 11: 64, 1932. Google Scholar2. Argonzdel Castillo JEB: A syndrome characterized by estrogenic insufficiency, galactorrhea, and decreased urinary gonadotropin, J. Clin. Endocrinol. and Metabolism 13: 79, 1953. CrossrefGoogle Scholar3. BourneWilliams AWLH: Recent advances in obstetrics and gynaecology, 1958, Little, Brown and Company, Boston. Google Scholar4. Brown JB: Urinary excretion of oestrogens during pregnancy, lactation, and the re-establishment of menstruation, Lancet 1: 704, 1956. CrossrefGoogle Scholar5. ChiariBraunSpaeth JCJ: Report of diseases of women observed during the years 1848-1855 incl., in Department of Gynecology (Municipal Clinic) in Vienna, Klin. der Geburtsh. u. Gynäk., Erlangen Ferdinand Enke 1855, p. 371-372. Google Scholar6. Christiansen EG: A case of Chiari-Frommers syndrome, Acta endocrinol. 24: 407, 1957. CrossrefMedlineGoogle Scholar7. Cushing H: Dyspituitarism: 20 years later with special consideration of pituitary adenomas, Arch. Int. Med. 51: 487, 1933. CrossrefGoogle Scholar8. Cushing H: The pituitary body and its disorders, 1912, J. B. Lippincott Company, Philadelphia, p. 24. Google Scholar9. Folley SJ: The physiology and biochemistry of lactation, 1956, Oliver and Boyd, Edinburgh. Google Scholar10. Folley SJ: Ciba Foundation colloquia on endocrinology, Vol. IV, 1952, The Blakiston Co., Philadelphia, p. 381. Google Scholar11. ForbesHennemanGriswoldAlbright APPHGCF: Syndrome characterized by galactorrhea, amenorrhea, and low urinary FSH, J. Clin. Endocrinol. and Metabolism 14: 265, 1954. CrossrefGoogle Scholar12. Frommel R: Concerning puerperal atrophy of the uterus, Ztschr. f. Geburtsh. u. Gynäk. 7: 305, 1882. Google Scholar13. FurthCliftonGadsenBuffett JKHELRF: Dependent and autonomous mammatrophic pituitary tumors in rats; their somatotropic features, Cancer Research 16: 608, 1956. MedlineGoogle Scholar14. Greenblatt RB: Report of an unusual case of lactation with notes on the suppression of lactation, Bull. Univ. Hosp. School of Med. Georgia Univ. 2: 1, 1940. Google Scholar15. GreenblattCarmonaHagler RBNWS: Chiari-Frommel syndrome, Obst. and Gynec. 7: 165, 1956. Google Scholar16. Grimm EG: Non-puerperal galactorrhea with case reports, Northwestern Univ. M. School Bull. 29: 350, 1955. MedlineGoogle Scholar17. GrossmanBuchbergBrecherHallinger SASELM: Idiopathic lactation following thoracoplasty, J. Clin. Endocrinol. 10: 729, 1950. CrossrefGoogle Scholar18. GrosvenorTurner CECW: Release and restoration of pituitary lactogen in response to nursing stimuli in lactating rats, Proc. Soc. Exper. Biol. and Med. 96: 723, 1957. CrossrefMedlineGoogle Scholar19. Hunt AB: Post-partum amenorrhea, Obst. and Gynec. 1: 522, 1953. Google Scholar20. Krestin D: Spontaneous lactation; association with enlargement of the pituitary with report of two cases, Lancet 1: 928, 1932. CrossrefGoogle Scholar21. LevinDaughadayLevy MEWHI: Persistent lactation associated with pituitary tumor and hyperadrenal corticism, Am. J. Med. 27: 172, 1959. CrossrefMedlineGoogle Scholar22. LyonsLiJohnson WRCHRE: The hormonal control of mammary growth and lactation, in Recent progress in hormone research, edited by Pincus, G., Vol. XIV, 1958, Academic Press, New York, p. 219 ff. Google Scholar23. MeitesTurner JCW: Studies concerning the mechanism controlling initiation of lactation at parturition, Endocrinology 31: 340, 1942. CrossrefGoogle Scholar24. Mendel EB: Chiari-Frommel syndrome; historical review with case report, Am. J. Obst. and Gynec. 51: 889, 1946. CrossrefMedlineGoogle Scholar25. Monroe JH: Abnormal lactation, North Carolina M. J. 18: 283, 1957. MedlineGoogle Scholar26. Randall LM: Amenorrhea not associated with pregnancy in young women, Am. J. Obst. and Gynec. 52: 975, 1946. CrossrefMedlineGoogle Scholar27. RubinNovak ICJ: Integrated gynecology, Vol. II, 1956, McGraw-Hill Book Co., New York, p. 432. Google Scholar28. Selye H: On the nervous control of lactation, Am. J. Physiol. 107: 535, 1934. CrossrefGoogle Scholar29. Slome C: Non-puerperal lactation in grandmothers, J. Pediat. 49: 550, 1956. CrossrefMedlineGoogle Scholar30. SalkinDavis DEW: Lactation following thoracoplasty and pneumonectomy, J. Thoracic Surg. 18: 580, 1949. CrossrefGoogle Scholar31. ToaffSadorsky RA: Galactorrhea and amenorrhea in pituitary adenomata, Exerpta Med. Sect. X (Obstetrics and Gynecology), Vol. V, No. 1966, 1952. Google Scholar32. Velardo JT (Editor): Essentials of human reproduction: clinical aspects, normal and abnormal, 1958, Oxford University Press, New York. Google Scholar33. Williams RH: Textbook of endocrinology, 1955, W. B. Saunders Co., Philadelphia. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Los Angeles, California*Received for publication December 8, 1959.From the Department of Medicine, University of Southern California School of Medicine, and the Endocrine Clinic of the Los Angeles County Hospital.†Trainee, National Institute of Arthritis and Metabolic Diseases, U. S. Public Health Service.Requests for reprints should be addressed to Albert E. White, M.D., Department of Medicine, University of Southern California School of Medicine, 1200 North State Street, Box 138, Los Angeles 33, California. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byMammary Stimulation causes Prolactin Secretion in Non-lactating WomenGynecomastia After Incision on the Thoracic CageThe central nervous system and disorders of ovulation in womenDiagnosis and Treatment of Abnormal Breast SecretionsLactation after Incision on the Thoracic Cage 1 June 1960Volume 52, Issue 6Page: 1264-1272KeywordsEstrogensGrowth hormoneHospital medicineLactationMilkOvulationPregnancyProgesteroneProlactinResearch laboratories ePublished: 1 December 2008 Issue Published: 1 June 1960 PDF downloadLoading ...