DIABETES MELLITUS AND CLINICAL RESEARCH: A STUDY OF INSULIN RESISTANCE
Authors: E DOWNIE
Journal: Annals of Internal Medicine (1957)

Article1 January 1957DIABETES MELLITUS AND CLINICAL RESEARCH: A STUDY OF INSULIN RESISTANCEEWEN DOWNIE, M.D., F.R.C.P., F.R.A.C.P.EWEN DOWNIE, M.D., F.R.C.P., F.R.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-46-1-126 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Excerpt"The secret—which is also the reward—of all learning lies in the passion for the search" (Quiller-Couch).Mr. President, distinguished guests and Fellows of the College, in thanking you for the invitation to deliver the Lilly Lecture for 1956 I recognize with pleasure the close professional relations which exist between our two countries and the compliment you have paid this day to Australian medicine. I am deeply conscious of my responsibility both to your College and to my colleagues at home.It has been my good fortune to visit this country three times within the past 12 years. On the first...Bibliography1. Allen FM: Total dietary regulation in diabetes mellitus, Monograph, Rockefeller Institute for Medical Research, No. 11, 1919. Google Scholar2. Downie E: The clinical approach to the problem of diabetes mellitus, Brit. M. J. 2: 863, 1955. CrossrefMedlineGoogle Scholar3. Rockey E: Total pancreatectomy for carcinoma, Ann. Surg. 118: 603, 1943. CrossrefMedlineGoogle Scholar4. Warren KW: Some aspects of total pancreatectomy, Lahey Clin. Bull. 7: 86, 1951. MedlineGoogle Scholar5. Root HF: Insulin resistance and bronze diabetes, New England J. Med. 201: 201, 1929. CrossrefGoogle Scholar6. Smelo LS: Insulin resistance, Proc. Am. Diabetes A. 8: 77, 1948. Google Scholar7. SoskinLevine SR: Carbohydrate metabolism, 2nd Ed., 1952, University of Chicago Press, Chicago, p. 315 et seq. Google Scholar8. BornsteinTrewhella JP: Plasma insulin levels in diabetes mellitus in man, Australian J. Exper. Biol. and M. Sc. 28: 569, 1950. CrossrefMedlineGoogle Scholar9. Hopkins FG: Biological thought and chemical thought: plea for unification (Linacre Lecture), Lancet 1: 1147, 1201, 1938. CrossrefGoogle Scholar10. RootIrvineEvansReinerCarpenter HFJWRDLTM: Absorption of insulin labelled with radioactive iodine in human diabetes, J. A. M. A. 124: 84, 1944. CrossrefGoogle Scholar11. Haldane JB: The scientific basis of medicine, Vol. III, 1954, Athlone Press, London, p. 45. Google Scholar12. HaugaardMarsh NJB: The action of insulin, 1st Ed. 1953, Charles C. Thomas, Springfield, Illinois. Google Scholar13. Bernard C: An introduction to the study of experimental medicine, 1949, Henry Schuman, New York, p. 217. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Melbourne,*Presented as the Lilly Lecture at the Thirty-seventh Annual Session of the American College of Physicians, Los Angeles, California, April 20, 1956.†Honorary Physician, Alfred Hospital, University of Melbourne, Australia.Requests for reprints should be addressed to Ewen Downie, M.D., 111 Collins Street, Melbourne C, Australia. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byInsulin resistance: looking back, looking forwardInsulin-Allergie und Insulin-ResistenzDie Insulintherapie: Die Behandlung des Coma diabeticumStudio degli anticorpi anti-insulina del siero umano in soggetti normali e diabeticiInsulinbindungskapazität des Serums bei Diabetikern mit erhöhtem InsulinbedarfSOME CLINICAL ASPECTS OF INSULIN ANTAGONISMINSULIN ANTIBODIES IN PREGNANCYNeue Erkenntnisse in der Behandlung der chronischen Insulinresistenz und experimentelle Untersuchungen zu ihrer GeneseOBSERVATIONS ON THE TREATMENT OF SEVERE DIABETIC KETOSISInsulin InsensitivityDiabetes Mellitus 1 January 1957Volume 46, Issue 1Page: 126-137KeywordsAcetonesBloodBlood plasmaDiabetes mellitusEthanolInsulinInsulin resistanceProteins ePublished: 1 December 2008 Issue Published: 1 January 1957 PDF downloadLoading ...