tbuckley/cabot-search huggingface dataset:
Abstract 161: Effectiveness of Lower Target Temperature Therapeutic Hypothermia for Post--Cardiac Arrest Victims Within 30 Minutes Resuscitation Interval
Authors: Tadashi Kaneko, Shunji Kasaoka, Ken Nagao, Naohiro Yonemoto, Hiroyuki Yokoyama, Hiroshi Nonogi
Journal: Circulation (2014)

Introduction: Therapeutic hypothermia (TH) for post cardiac arrest syndrome (PCAS) patients is standard strategy to reduce brain damage. However, current randomized control study (TTM: Target temperature management study, N Engl J Med 2013) suggested that simple target temperature did not improve outcome. Furthermore, there is no evidence, whether target temperature would be changed for each status of PCAS patients. Hypothesis: Lower target temperature could improve neurological outcome in PCAS patients. Methods: Participants with J-PULSE-Hypo study database were divided into the L group (32.0-33.9°C) and the M group (34-35°C). The favorable neurological outcomes (%, CPC 1-2 on 30th day) were compared between L and M groups in all and each subgroups with propensity score analysis with IPTW (inverse probability of treatment weighting) method as multivariate analysis. The subgroups were ages and interval from collapse to ROSC (return of spontaneous circulation). Results: 477 participants were analyzed. The comparison of each groups for favorable neurological outcome were that all groups (L: 64%, n = 42, vs M: 55%, n= 424, P = 0.234, multivariate: P = 0.452), age (≤60 y.o.) (L: 70% vs M: 67%, P = 0.717, multivariate: P = 0.657), age (&gt;60 y.o.) (L: 50% vs M: 44%, P = 0.665, multivariate: P = 0.061), interval from collapse to ROSC (≤30 min.) (L: 88% vs M: 64%, P = 0.022, multivariate: P = 0.007), and interval from collapse to ROSC (&gt;30 min.) (L: 21% vs M: 29%, P = 0.567, multivariate: P = 0.449). Conclusions: The PCAS victims within 30 min. from collapse to ROSC, would be treated by TH with less than 34°C target temperature.
Oral liken planusta oral betametazon mini-puls tedavinin topikal triamsinolon asetonid (% .1) pat ile kıyaslanması: Randomize karşılaştırmalı bir çalışma
Authors: Amit K. Malhotra, Binod K. Khaitan, Gomathy Sethuraman veVinod K. Sharma, New Delhi
Journal: Journal of the American Academy of Dermatology (2008)
Abstract P328: Estimating the Population Distribution of Usual 24-Hour Sodium Excretion From Timed-Spot Urine Specimens Among Adults 18-39 Years
Authors: Chia-Yih Wang, Alicia L Carriquiry, Te-Ching Chen, Catherine M Loria, Christine M Pfeiffer, Kiang Liu, Christopher T Sempos, Cria G Perrine, Mary E Cogswell
Journal: Circulation (2015)

Introduction: National efforts toward reducing population sodium intake necessitate developing a feasible and valid monitoring method, especially for the distribution tails given about 90% of the US population consumes more sodium than recommended. Objective: We developed and tested the validity of a statistical approach using one or two timed-spot urines to estimate population distribution of usual 24-hour sodium excretion. Methods: A convenience sample of 407 adults, 18-39 years of age, (54% female, 48% black) collected urine for a 24-hour period, placing each void in a separate container. Of these, 133 repeated the procedure 4-11 days later. Four timed-spot specimens (morning, afternoon, evening, and overnight) were selected from each 24-hour collection. We developed gender-specific equations using Fuller’s error-in-the-equation measurement error model to calibrate total sodium excreted in each of the one-spot (e.g., morning) and combined two-spot (e.g., morning + afternoon) urines to 24-hour sodium excretion. The calibrated sodium excretions were used to estimate the population distribution of usual 24-hour sodium excretion. Participants were then randomly assigned to modeling (n=160) or validation (n=247) groups to examine the bias in estimated population percentiles. Results: Median bias in predicting the 5 th , 25 th , 50 th , 75 th , and 95 th population percentiles of usual 24-hour sodium excretion with one-spot urine ranged from -367 to 284 mg (-7.7 to 12.2% of the observed usual excretions) for men and -604 to 486 mg (-14.6 to 23.7%) for women, and with two-spot urines from -338 to 263 mg (-6.9 to 10.4%) and -166 to 153 mg (-4.1 to 8.1%), respectively. Four of the six two-spot urine combinations produced no significant bias in predicting selected percentiles. Conclusions: Our approach to estimate the population distribution of usual 24-hour sodium excretion using calibrated spot urine sodium accounted for day-to-day variation and covariance between measurement errors, and produced percentile estimates with relatively low biases across low to high sodium levels. This may provide a low-burden, low-cost alternative to 24-hour collections in monitoring population sodium intake among healthy young adults and merits further investigation in other population subgroups.
Abstract 1509: A ARMS-PNA PCR assay for detection of EGFR mutations in FFPE tumor samples
Authors: Shanshan Zhao, Xiao Guo, Ziwen Long, Dehua Yu
Journal: Cancer Research (2014)

Abstract The activating mutations of Epidermal growth factor receptor (EGFR) are the predictive markers for response to tyrosine kinase inhibitors gefitinib and erlotinib in non-small cell lung cancer(NSCLC). Therefore detection of EGFR mutations will guide effective therapeutical options for patients with NSCLC. Here we developed a new method for the rapid and reliable detection of EGFR mutations by using a combination of modified mutation-specific ARMS primers and peptide nucleic acid (PNA) clamping system, named ARMS-PNA assay. In this real-time PCR system, the wild-type EGFR DNA is completely blocked by PNA with a higher annealing temperature, and the mutant gene is selectively amplified by the modified ARMS primers and the amplicon extending signals are collected by the taqman-probe at the same time. The ARMS-PNA assay could detect 29 mutations on EGFR gene with a sensitivity of 0.5% under the background of a total of 10ng wild-type genomic DNA. By using this assay, we analyzed the EGFR mutations in 1033 Chinese NSCLC FFPE samples in comparison with Sanger sequencing. Our results showed that the positive rates were 50.1%, which were higher than that measured by Sanger sequencing (48.3%). The coincidence rates of the two methods were 99.0% for the positive samples and 95.5% for the negative samples. The total coincidence rate was 97.2%. In conclusion, our study provides a basis for the detection of somatic mutations in EGFR in a routine clinical setting. The ARMS-PNA PCR assay allows the detection of the activating EGFR mutations in FFPE samples with better sensitivity and feasibility than the current assays used in clinic.&amp;lt;!–EndFragment–&amp;gt; Citation Format: Shanshan Zhao, Xiao Guo, Ziwen Long, Dehua Yu. A ARMS-PNA PCR assay for detection of EGFR mutations in FFPE tumor samples. [abstract]. In: Proceedings of the 105th Annual Meeting of the American Association for Cancer Research; 2014 Apr 5-9; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2014;74(19 Suppl):Abstract nr 1509. doi:10.1158/1538-7445.AM2014-1509
Abstract 16319: Distribution and Severity of Myocardial Ischemia Modify Mitral Regurgitation (MR) Response to Percutaneous Coronary Intervention (PCI)
Authors: Parag Goyal, Samuel C Volo, Attila Feher, Maya M Petashnick, Sergey Gurevich, Jonathan D Kochav, Polydoros Kampaktsis, Robert M Levine, Mark Ratcliffe, Franklin J Wong, Leonard N Girardi, Richard B Devereux, Jonathan W Weinsaft
Journal: Circulation (2014)

INTRODUCTION: Myocardial properties impact mitral valve closure, but MR response to PCI is poorly understood. This study tested if PCI alone can improve MR and whether MR change is predicted by myocardial ischemia pattern. METHODS: The population comprised consecutive patients with perfusion evidenced ischemia and no intrinsic mitral valve disease undergoing echocardiography (echo) and PCI. Stress SPECT myocardial perfusion imaging (MPI) was used to measure rest perfusion and inducible ischemia via a 17 segment model, 5 point per segment scoring system. Echo (within 1 week of MPI) measured MR and LV chamber dimensions; followup echo (≥1 month post PCI) assessed change in MR. RESULTS: 358 patients undergoing PCI (50% LAD
Abstract P020: Multivitamin Use and Risk of Hypertension in Prospective Cohort Study of Women
Authors: Susanne Rautiainen, Lu Wang, I-Min Lee, J. Michael Gaziano, Julie E Buring, Howard D Sesso
Journal: Circulation (2015)

Introduction: Despite the widespread use of multivitamin supplements, little is known regarding its effects on blood pressure (BP) and the development of hypertension. We therefore sought to prospectively investigate how multivitamin use was associated with incident hypertension among middle-aged and older women. Hypothesis: Multivitamin use is associated with the risk of hypertension among middle-aged and older women. Methods: We studied 29,082 women from the Women’s Health Study aged ≥45 years and free of cardiovascular disease, cancer and hypertension at baseline. At baseline, women self-reported lifestyle, clinical and dietary factors, including multivitamin and supplement use. Cases of incident hypertension were identified during an average of 11.5 years follow-up through self-reports from annual follow-up questionnaires. Incident hypertension was defined as either a new diagnosis of hypertension by a physician, initiation of antihypertensive medication, systolic BP ≥140 mmHg, or diastolic BP ≥90 mmH...
Cycles of sex and diseaseSeasonal Patterns of Stress, Immune Function, and Disease by Randy J. Nelson, Gregory E. Demas, Sabra L. Klein, and Lance J. Kriegsfeld. Cambridge University Press, 2002. US$70.00 (xv+291 pages) ISBN 0 521 59068 X
Authors: J JOHNSON
Journal: Trends in Endocrinology and Metabolism (2003)
Abstract 12232: Gender Differences in Microvascular Vasomotor Response to Mental Stress in Patients With Stable Coronary Artery Disease
Authors: Ronnie Ramadan, David Sheps, Shabnam Seydafkan, Ayman Khoder, Malik Obideen, Ibhar Al Mheid, Fabio Esteves, Paolo Raggi, Michael Kutner, Douglas Bremner, Arshed Quyyumi, Viola Vaccarino
Journal: Circulation (2013)

Introduction: Evidence supports gender-specific pathophysiological differences in the presentation and risk profile of cardiovascular disease, and microvascular disease has been proposed as a mecha...
HYPERPARATHYROIDISM WITH RATHER RAPID RECALCIFICATION OF BONE FOLLOWING THE REMOVAL OF AN ADENOMA
Authors: Thomas P. Sprunt
Journal: Annals of Internal Medicine (1938)

Case Reports1 July 1938HYPERPARATHYROIDISM WITH RATHER RAPID RECALCIFICATION OF BONE FOLLOWING THE REMOVAL OF AN ADENOMATHOMAS P. SPRUNT, M.D., F.A.C.P.THOMAS P. SPRUNT, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-12-1-121 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe body's calcium is obtained of course from the food. Its absorption from the intestinal tract is aided by vitamin D. In the blood stream the amounts of calcium and phosphorus are maintained at the so-called normal steady level as physiological constants by the activity of the parathyroid glands which govern the deposit or the resorption of calcium and phosphorus from the storehouses in the bones. The bones therefore play an important part in the metabolism of these elements in addition to furnishing the rigidity of the skeleton and spaces for the bone marrow or blood building organs.We have...References1. WILDERHOWELL RMLP: Etiology and diagnosis in hyperparathyroidism, Jr. Am. Med. Assoc., 1936, cvi, 427-431. CrossrefGoogle Scholar2. MCLEANHASTINGS FCAB: Clinical estimation and significance of calcium-ion concentrations in the blood, Am. Jr. Med. Sci., 1935, clxxxix, 601-613. Google Scholar3. ALBRIGHTAUBBAUER FJCW: Hyperparathyroidism, Jr. Am. Med. Assoc., 1934, cii, 1276-1287. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Baltimore, Maryland*Received for publication September 7, 1937. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byÜBER HYPER-PARATHYREOIDISMUS EIN OPERIERTER FALL MIT SCHWEREN NIERENVERÄNDERUNGEN 1 July 1938Volume 12, Issue 1Page: 121-127KeywordsBloodBoneCalciumFoodHyperparathyroidismParathyroidPhosphorusRiversSkeletonVitamin D ePublished: 1 December 2008 Issue Published: 1 July 1938 PDF downloadLoading ...
Additive Beneficial Effects of Beta-Blockers to Angiotensin-Converting Enzyme Inhibitors in the Survival and Ventricular Enlargement (SAVE) Study fn1fn1This study was supported by a University-Industry grant from the Medical Research Council, Ottawa, Ontario, Canada and Bristol Myers Squibb, Montreal, Quebec, Canada.
Authors: Pascal Vantrimpont, Jean L. Rouleau, Chuan-Chuan Wun, Antonio Ciampi, Marc Klein, Bruce Sussex, J.Malcolm O. Arnold, Lemuel Moyé, Marc Pfeffer
Journal: Journal of the American College of Cardiology (1997)
EVALUATION OF THE ERYTHROCYTE SEDIMENTATION TEST IN LEPROSY: STATISTICAL STUDY OF MORE THAN TWO THOUSAND TESTS IN MORE THAN FIVE HUNDRED PATIENTS
Authors: G. H. Faget
Journal: Annals of Internal Medicine (1945)

Article1 February 1945EVALUATION OF THE ERYTHROCYTE SEDIMENTATION TEST IN LEPROSY: STATISTICAL STUDY OF MORE THAN TWO THOUSAND TESTS IN MORE THAN FIVE HUNDRED PATIENTSG. H. FAGETG. H. FAGETSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-22-2-213 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe changes in the erythrocyte sedimentation test which occur during the course of leprosy have not been studied as thoroughly as they have in tuberculosis. Although this laboratory procedure has been employed in both diseases for approximately the same period of time, it has met with great popularity in tuberculosis whereas comparatively few articles on the subject are extant in the literature on leprosy. Not all investigators are in accord as to the significance of this test in leprosy. Many, including Landeiro,1Muir,2and Schujman,3report that it bears a close relationship to the type of disease, being rapid in...Bibliography1. LANDEIRO F: La vitesse de sedimentation des hematies chez les leupreux, Compt.-rend. Soc. de biol., 1926, xcv, 1261. Google Scholar2. MUIR E: The erythrocyte sedimentation test in leprosy, Internat. Jr. Leprosy, 1937, v, 419. Google Scholar3. SCHUJMAN S: Value of erythrocyte sedimentation in leprosy, Revista méd. del Rosario (Rep. Argentina), 1935, xxv, 697; 763. Google Scholar4. MUIR E: Erythrocyte sedimentation test in leprosy, Indian Med. Gaz., 1929, lxiv, 488. Google Scholar5. KERR I: Value of the sedimentation test in treatment of leprosy, Indian Med. Gaz., 1929, lxiv, 247. Google Scholar6. HELLERPAUL VGH: Changes in cell volume produced by varying concentrations of different anticoagulants, Jr. Lab. and Clin. Med., 1934, xix, 777. Google Scholar7. KOLMERBOERNER JAF: Approved laboratory technic, ed. 2, 1938, D. Appleton-Century Co. Inc., New York, p. 102. Google Scholar8. WINTROBELANDSBERG MNJW: A standardized technic for the blood sedimentation test, Am. Jr. Med. Sci., 1935, clxxxix, 102. CrossrefGoogle Scholar9. TAPPANFAGET JWGH: The red blood cell sedimentation test in the treatment of tuberculosis, Southwest. Med., 1929, xiii, 105. Google Scholar10. ROWE AH: Albumin and globulin content of human blood serum, Arch. Int. Med., 1916, xviii, 455. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: U. S. P. H. S. Carville, Louisiana*Received for publication June 16, 1944. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 February 1945Volume 22, Issue 2Page: 213-224KeywordsLeprosyResearch laboratories ePublished: 1 December 2008 Issue Published: 1 February 1945 PDF downloadLoading ...
The Micromorphology of a Salivary-Gland Tumor of a Mouse Infected with Polyoma Virus&lt;xref ref-type="fn" rid="FN1"&gt;2&lt;/xref&gt;
Authors: George A. Edwards, Rita F. Buffett, Jacob Furth
Journal: JNCI Journal of the National Cancer Institute (1960)

A salivary-gland tumor from a mouse infected at birth with polyoma virus was studied with the electron microscope. Intranuclear, intracytoplasmic, and intercellular particles were observed. Intranuclear particles average 30 mµ and appear to be associated with fine filamentous material. Viruses of 80 mµ similar in structure to leukemia viruses were seen at the cell borders. Both plasma membrane and filamentous material in the cortical cytoplasm appear involved in their formation. Cytoplasmic virus particles associated with mitochondria and inclusion bodies are of size and structure similar to the intranuclear particles. Crystalline aggregates may occur in the inclusion body. Intercellular virus particles include dense forms of 30 mµ identified as polyoma virus, double-membraned forms of 80 or more mµ containing a nucleoid and tentatively identified as leukemia virus, single-membraned forms of 60 to 70 mµ containing an eccentric nucleoid such as the mammary-tumor agent contains, although smaller than the latter, and single-membraned forms of 65 to 70 mµ containing unidentified particles and vesicles. Smaller vesicles of 33 to 52 mµ also occur in the peripheral cytoplasm and intercellular spaces. Their relation to the tumor viruses is undetermined.
Transgenically Produced Human Antithrombin: Structural and Functional Comparison to Human Plasma–Derived Antithrombin
Authors: Tim Edmunds, Scott M. Van Patten, Julie Pollock, Eric Hanson, Richard Bernasconi, Elizabeth Higgins, Partha Manavalan, Carol Ziomek, Harry Meade, John M. McPherson, Edward S. Cole
Journal: Blood (1998)
Targeted deep sequencing identifies rare loss-of-function variants in IFNGR1 for risk of atopic dermatitis complicated by eczema herpeticum
Authors: Li Gao, Lianghua Bin, Nicholas M. Rafaels, Lili Huang, Joseph Potee, Ingo Ruczinski, Terri H. Beaty, Amy S. Paller, Lynda C. Schneider, Rich Gallo, Jon M. Hanifin, Lisa A. Beck, Raif S. Geha, Rasika A. Mathias, Kathleen C. Barnes, Donald Y.M. Leung
Journal: Journal of Allergy and Clinical Immunology (2015)
Genetic Factors in Exceptional Longevity
Authors: George K Andrikopoulos, Dimitri J Richter
Journal: JAMA (2004)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Reproductive Medicine Experts Till an Increasingly Fertile Field
Authors: D F Phillips
Journal: JAMA (1998)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 772: CCL2 regulates EMT-mediated chemo-resistance in prostate cancer
Authors: Wenchu Wang, Yi Lu, Xiaolin Zhou, Atsushi Mizokami, Evan Keller, Jian Zhang
Journal: Cancer Research (2014)

Abstract Prostate cancer is one of the most common cancers and the second leading cause of cancer-related death in western countries. In China, the incidence has increased, unexpectedly and sharply, for the past 20 years. Chemo-resistance, in various types of tumor including prostate cancer, is one of the critical problems in cancer therapy. In prostate cancer, for example, the resistance to taxanes (paclitaxel or docetaxel, DTX) accounts for tumor relapse and progression resulting in skeletal metastasis and high mortality. Epithelial-mesenchymal transition (EMT) has been suggested as a key process that dominates chemo-resistance through unknown mechanisms. In the current study, we reported that CCL2 serves as key molecules in EMT-mediated chemo-resistance in prostate cancer cells using paclitaxel-resistant cells, DU145-TxR, PC-3-TxR and C4-2B-TxR. Parental prostate cancer cells were used as controls. We observed that DU145-TxR, PC-3-TxR and C4-2B-TxR cells produced significantly higher amount of CCL2 compared to their parental cells, determined by cytokine array. In addition, DU145-TxR, PC-3-TxR and C4-2B-TxR cells demonstrated EMT phenotypes including hall maker changes in E-cadherin and Vimentin expression and transcriptional factor (Snail, ZEB1, and Slug) alterations, examined by western blot. These changes were reversed partially by adding neutralizing antibodies against CCL2. Finally DU145-TxR, PC-3-TxR, and C4-2B-TxR or their parental cells were implanted into SCID mice and the mice were given DTX (10mg/kg, biweekly) and tumor growth was monitored for 4 weeks. Both DU145-TxR, PC-3-TxR and C4-2B-TxR tumors grew faster than the parental tumors. Tumor tissues were collected and total RNAs were isolated. Levels of CCL2 expression in these tumors were significantly higher in DU145-TxR, PC-3-TxR and C4-2B-TxR tumors. IHC analysis confirmed corresponding staining of EMT markers such as E-cadherin and Vimentin expression. Together we concluded that CCL2 regulates EMT-mediated chemo-resistance in prostate cancer. These results are of high impact of human prostate cancer chemotherapy. Supported by U.S. Department of Defense PC061231; NSF key project 81130046; NSF projects 81171993 and 81272415. Citation Format: Wenchu Wang, Yi Lu, Xiaolin Zhou, Atsushi Mizokami, Evan Keller, Jian Zhang. CCL2 regulates EMT-mediated chemo-resistance in prostate cancer. [abstract]. In: Proceedings of the 105th Annual Meeting of the American Association for Cancer Research; 2014 Apr 5-9; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2014;74(19 Suppl):Abstract nr 772. doi:10.1158/1538-7445.AM2014-772