According to Lynch , Lost Highway differs from conventionally logic stories and it is a psychogenic fugue that has been partially influenced by the O.J . Simpson murder trial .
Lost Highway follows a musician ( Pullman ) who begins receiving mysterious VHS tapes of him and his wife ( Arquette ) in their home , and who is suddenly convicted of murder , after which he inexplicably disappears and is replaced by a young mechanic ( Getty ) leading a different life .
Lost Highway -LRB-film-RRB-