Powers Boothe , Chris Noth , Anthony LaPaglia , Steven Blum , Fred Tatasciore , Jason Isaacs , Kevin Michael Richardson , Mark Rolston , John DiMaggio , and James Woods are some of the voice actors who have played Lex Luthor in animated adaptations .
Clancy Brown , James Marsters , and others have provided the character 's voice in animation adaptations.
Lex Luthor