Tricyclic Antidepressants are sometimes prescribed for depressive disorders .
Although TCAs are sometimes prescribed for depressive disorders , they have been largely replaced in clinical use in most parts of the world by newer antidepressants such as selective serotonin reuptake inhibitors ( SSRIs ) , serotonin-norepinephrine reuptake inhibitors ( SNRIs ) and norepinephrine reuptake inhibitors ( NRIs ) .