A 2-approximation for the preceding-and-crossing structured 2-interval pattern problem
The 2-interval pattern problem over its various models and restrictions was proposed by Vialette (2004) for the application of RNA secondary structure prediction. We present an O(n(3) log n)-time 2-approximation algorithm for the problem of finding a largest {<, }-structured subset of 2-intervals given an input 2-interval set of size n. This greatly improves the previous best approximation ratio of 6 by Crochemore et al. (2005).
2-interval rna secondary structure prediction approximation algorithms