New Genetic Insights in Familial Hyperaldosteronism
Aldosterone, the major circulating mineralocorticoid, particiates in blood volume and serum potassium homeostasis. Primary aldosteronism is a disorder characterized by hypertension and, in more severe form, hypokalemia, due to autonomous aldosterone secretion from the adrenocortical zona glomerulosa. Improved screening techniques, particularly application of the plasma aldosterone
genetics familial primary aldosteronism diagnosis glucocorticoid-remediable hyperaldosteronism fh-ii