Esophageal disease: updated information on inflammation
The following on esophageal disease provides updated information the mucosal defense against acid and acidpepsin injury; the roles of platelet activating factor, mast cells, proinflammatory cytokines, and chemokines in inflammation; differences and similarities in erosive and nonerosive esophagitis; acid and vanilloid receptors in esophageal mucosa; and bile acid receptors in esophageal epithelium.
esophagitis platelet activating factor cytokines tight junction adherens junction claudins e-cadherin paracellular permeability dilated intercellular spaces gastro-esophageal reflux squamous cells trpv-1 receptor substance p inflammatory mediators nonerosive reflux disease chemosensitive nociceptors adenocarcinoma nox5-s tgr5