Transcriptome meta-analysis reveals a central role for sex steroids in the degeneration of hippocampal neurons in Alzheimers disease
Alzheimers disease is the most prevalent form of dementia. While a number of transcriptomic studies have been performed on the brains of Alzheimers specimens, no clear picture has emerged on the basis of neuronal transcriptional alterations linked to the disease. Therefore we performed a meta-analysis of studies comparing hippocampal neurons in Alzheimers disease to controls.
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