Computational studies on strain transmission from a collagen gel construct to a cell and its internal cytoskeletal filaments
A tissue model having a cell with cytoskeletal filaments (CSKs) is developed. Mechanical interactions between tissue, cell and CSKs are examined. The type of a tissue deformation is reflected in the distribution of CSK strain. The distribution of CSK strain varies with the Young?s modulus of the tissue.
strain transmission cell tissue biomechanics cytoskeleton