IA, database of known ligands of aminoacyl-tRNA synthetases
The IA database contains 240 structures of known inhibitors of aminoacyl- tRNA synthetases. Structures can be downloaded in different file formats (mol, sdf, smile, png). The search engine offers possibility of searching for the ligands with a given functional group. Additionally, one can search for ligands that act on selected synthetases and from particular references. The data include information which synthetase a given ligand inhibits together with the inhibition constant (IC50) if known.
aminoacyl-trna synthetases aminoacyl-trna synthetases inhibitors molecular docking virtual high throughput screening