Universality splitting in distribution of number of miRNA co-targets
In a recent work (Basu et al., in EPL 105:28007, 2014) it was pointed out that the link-weight distribution of microRNA co-target network of a wide class of species are universal up to scaling. The number cell types, widely accepted as a measure of complexity, turns out to be proportional to these scale-factor. In this article we discuss additional universal features of these networks and show that, this universality splits if one considers distribution of number of common targets of three or more number of microRNAs. These distributions for different species can be collapsed onto two distinct set of universal functions, revealing the fact that the species which appeared in early evolution have different complexity measure compared to those appeared late.
universality microrna network co-regulation