Molecular Mechanism of the Life and Death of the Osteoclast
The life span of osteoclasts is critically regulated by various cytokines, and therapeutics such as bisphosphonates act directly on osteoclasts and induce apoptosis of the cells. This article will focus on the molecular mechanism of osteoclast apoptosis and summarize the recent advances in this field with an emphasis on the role of intracellular signaling pathways
osteoclast cytokines apoptosis akt tnf rac1 bim