Parameter-dependent behavior of articular cartilage: 3D mechano-electrochemical computational model
A parameter-dependent analysis of articular cartilage is developed through a specific computational model. The results show how Young's modulus and Poisson coefficient control tissue behavior rather than electrochemical properties. Ion diffusivity and ion activity coefficients appear to be vital in controlling velocity of incoming and outgoing fluxes. This parametric study establishes a basic guide the essential properties to be included into computational modeling of articular cartilage. The model provides a helpful tool in articular cartilage simulations.
articular cartilage ion diffusivity ion activity coefficient parametric analysis mechano-electrochemical model cartilage young's modulus