Noninvasive Prenatal Diagnostic Assay for the Detection of ?-Thalassemia
The development of a noninvasive method for detection of ?-thalassemia in the population of Cyprus is based on the detection of paternally inherited single nucleotide polymorphisms (SNPs) as well as ?-thalassemia (?-thal) mutations. We selected 11 informative SNPs for the Cypriot population linked to the ?-globin locus. Two different approaches were use
noninvasive prenatal diagnosis (nipd) thalassemia microarrays