protein structure similarity detection using alignment of secondary structure elements and their geometric properties
Proteins are presented with sequences of secondary structure elements - helices and sheets, which compose them. Geometric properties of protein chains are considered, when distance factors are computed. Each distance factor shows relative position of two compared elements. Protein structures are compared by an alignment algorithm, applied to sequences of secondary structure elements. A measure of similarity at each step is not only calculated by a simple comparison of two elements, but with the active use of corresponding distance factors.
protein structure similarity detection secondary structure alignment algorithm