Probability distribution function-based classification of structural MRI for the detection of Alzheimers disease
PDF based feature extraction is introduced for the representation of sMRI. Voxels within statistically obtained 3D masks are used to generate localized PDFs. Dimensionality reduction of PDF is provided by determining optimum number of bins. Fisher criterion is used to determine the optimal dimension of PDF vector.
classification structural mri alzheimers disease fisher criterion voxel-based morphometry probability distribution function statistical feature extraction computer-aided diagnosis