MC3: a steady-state model and constraint consistency checker for biochemical networks
Stoichiometric models provide a structural framework for analyzing steady-state cellular behavior. Models are developed either through augmentations of existing models or more recently through automatic reconstruction tools. There is currently no standardized practice or method for validating the properties of a model before placing it in the public domain. Considerable effort is often required to understand a models inconsistencies before its reuse within new research efforts.
constraint-based modeling pathway analysis model validation consistency checking model reuse