HiCdat: a fast and easy-to-use Hi-C data analysis tool
The study of nuclear architecture using Chromosome Conformation Capture (3C) technologies is a novel frontier in biology. With further reduction in sequencing costs, the potential of Hi-C in describing nuclear architecture as a phenotype is only about to unfold. To use Hi-C for phenotypic comparisons among different cell types, conditions, or genetic backgrounds, Hi-C data processing needs to be more accessible to biologists.
hi-c data analysis nuclear architecture chromosome conformation capture (3c) sample comparison structural domains correlation to (epi-)genome