Whole-exome sequencing enhances prognostic classification of myeloid malignancies
A robust prognostic classifier built from exome sequencing data. Prognostic categories are strongly reproducible in an independent validation set. Classifier that operates in a pan-diagnostic manner (MDS, MDS/MPN, and AML). Classifier outperforms standard prognostic classifiers within diagnoses. Classifier is distributed publicly as a web-based tool.
exome sequencing myeloid malignancy patient prognosis mutation random forests