A novel biological role for nsLTP2 from Oriza sativa: Potential incorporation with anticancer agents, nucleosides and their analogues
Nonspecific lipid transfer protein (nsLTP2) binds with nucleosides and anticancer drugs. Hydrophobicity of the active site plays prominent role in this regard. Purine analogues drugs presented higher affinity than pyrimidine counterparts. Binding affinity is influenced by the modifications occurring in the base and sugar moiety of the ligands.
nsltp2 anti-viral drugs anti-cancer agents drug delivery