Tetramer formation in Arabidopsis MADS domain proteins: analysis of a protein-protein interaction network
MADS domain proteins are transcription factors that coordinate several important developmental processes in plants. These proteins interact with other MADS domain proteins to form dimers, and it has been proposed that they are able to associate as tetrameric complexes that regulate transcription of target genes. Whether the formation of functional tetramers is a widespread property of plant MADS domain proteins, or it is specific to few of these transcriptional regulators remains unclear.
tetramers mads domain proteins protein-protein interaction network transcription factors subgraph abundance arabidopsis thaliana