DiSNPindel: improved intra-individual SNP and InDel detection in direct amplicon sequencing of a diploid
Amplicon re-sequencing based on the automated Sanger method remains popular for detection of single nucleotide polymorphisms (SNPs) and insertion-deletion polymorphisms (InDels) for a spectrum of genetics applications. However, existing software tools for detecting intra-individual SNPs and InDels in direct amplicon sequencing of diploid samples are insufficient in analyzing single traces and their accuracy is still limited.
diploid single nucleotide polymorphism (snp) insertion-deletion (indel) resequencing