An in silico MS/MS library for automatic annotation of novel FAHFA lipids
A new lipid class named fatty acid esters of hydroxyl fatty acids (FAHFA) was recently discovered in mammalian adipose tissue and in blood plasma and some FAHFAs were found to be associated with type 2 diabetes. To facilitate the automatic annotation of FAHFAs in biological specimens, a tandem mass spectra (MS/MS) library is needed. Due to the limitation of the commercial available standard compounds, we proposed building an in silico MS/MS library to extend the coverage of molecules.
ms/ms fahfa lipids in silico library