Invariance and plasticity in the Drosophila melanogaster metabolomic network in response to temperature
Metabolomic responses to extreme thermal stress have recently been investigated in Drosophila melanogaster. However, a network level understanding of metabolomic responses to longer and less drastic temperature changes, which more closely reflect variation in natural ambient temperatures experienced during development and adulthood, is currently lacking. Here we use high-resolution, non-targeted metabolomics to dissect metabolomic changes in D. melanogaster elicited by moderately cool (18C) or warm (27C) developmental and adult temperature exposures.
drosophila melanogaster metabolomics networks temperature differential coexpression