Of text and gene  using text mining methods to uncover hidden knowledge in toxicogenomics
Toxicogenomics studies often profile gene expression from assays involving multiple doses and time points. The dose- and time-dependent pattern is of great importance to assess toxicity but computational approaches are lacking to effectively utilize this characteristic in toxicity assessment. Topic modeling is a text mining approach, but may be used analogously in toxicogenomics due to the similar data structures between text and gene dysregulation.
toxicogenomics topic modeling latent dirichlet allocation text-mining systems biology