Predicting helix pair structure from fuzzy contact maps
We incorporate fuzzy logic to create fuzzy contact maps for helix pairs. Similar distance map regions to a query are retrieved based on fuzzy contact map similarity. Retrieved distance map regions are used to predict a distance map using bound smoothing. The EMBED algorithm is used on the predicted distance map to obtain 3D structure. We obtain good structures at various levels of noise.
helix fuzzy contact map contact map protein structure distance constraints