CombAlign: a code for generating a one-to-many sequence alignment from a set of pairwise structure-based sequence alignments
In order to better define regions of similarity among related protein structures, it is useful to identify the residue-residue correspondences among proteins. Few codes exist for constructing a one-to-many multiple sequence alignment derived from a set of structure or sequence alignments, and a need was evident for creating such a tool for combining pairwise structure alignments that would allow for insertion of gaps in the reference structure.
multiple sequence alignment multiple structure alignment matrix protein msa mssa vp40 secreted glycoprotein sgp ebola