C-Type Natriuretic Peptide Is Specifically Augmented by Pituitary Adenylate Cyclase-Activating Polypeptide in Rat Astrocytes
In rat-cultured astrocytes, pituitary adenylate cyclase-activating polypeptide (PACAP) activates gene expression and secretion of C-type natriuretic peptide (CNP) in a dose- and time-dependent manner. These results suggest that PACAP might be involved in the regulation of CNP biosynthesis in astrocytes
astrocytes pacap ria rt-pcr