Non-invasive evaluation of breast cancer response to chemotherapy using quantitative ultrasonic backscatter parameters
The non-invasive quantitative ultrasound backscatter parameter estimation technique described in this manuscript has the potential of assess tumor microstructure and detecting tumor responses to neoadjuvant chemotherapy in patients with LABC and separating clinical responders from non-responders as early as 14weeks, after the start of chemotherapy. This is important for customization therapies for non-responding patients early after treatment initiation. This finding suggests that it is possible to use this method to aid clinicians in making decisions to modify cancer therapy early on and personalize treatment.
breast cancer chemotherapy quantitative ultrasound scattering property clinical response