The Presentation of Haptenated Proteins and Activation of T Cells in the Mesenteric Lymph Nodes by Dendritic Cells in the TNBS Colitis Rat
We described the role of dendritic cells (DCs) in aspects of T cell activation at the mesenteric lymph nodes (MLN) in trinitrobenzene sulfonic acid (TNBS)-induced colitis. An antigenic-immune response is induced at the MLN, and dendritic cells are the affected cell type. Cross-linking and GRO/CINC-1 have synergistic effects for DC maturation.
cytokine th1 inflammatory bowel disease antigen-presenting cell function chemokine