Finding the closest ultrametric
Ultrametrics  model the pairwise distances between living species, where the distance is measured by hereditary time. Reconstructing the tree from the ultrametric distance data is easy, but only if our data is exact. We consider the NP -complete problem of finding the closest ultrametric to noisy data, as modeled by multiplicative or additive total distortion, with or without a monotonicity assumption on the noise. We obtain approximation ratio O(logn) O ( log n ) for multiplicative distortion where n n is the number of species, and O(1+(??1)?1) O ( 1 + ( ? ? 1 ) ? 1 ) for additive distortion where ? ? is the minimum ratio of any two distinct input distances. As part of proving our approximation bound for additive distortion, we give the first constant-factor approximation algorithm for a previously-studied problem called Cluster Deletion.
ultrametric approximation algorithm cluster deletion phylogenetic reconstruction