Early Diagnosis of Rickettsioses by Electrochemiluminscence
The diagnosis of acute rickettsioses during the acute phase of the disease is challenging. We present preliminary evidence that antigen-capture using streptavidin-coated magnetic beads with biotinylated anti-rickettsia typhi rabbit polyclonal antibodies followed by electrochemiluminescent detection with ruthenylated antibodies of the same specificity could be used for the diagnosis of rickettsial diseases in the acute phase
rickettsioses electrochemiluminescence rickettsia typhi ruthenium (ii) tris-bipyridine tripropylamine