A promising enantioselective Diels-Alder dienophile by computer-assisted rational design: 2,5-diphenyl-1-vinyl-borolane
Several chiral vinylboranes have been theoretically evaluated as enantioselective Diels - Alder dienophiles. Theoretical results suggest that optically pure 2,5-diphenyl-1-vinyl-borolane should be the reagent of choice for performing such transformations efficiently.
asymmetric synthesis boranes cycloadditions density functional calculations ligand design