Modeling of high sodium intake effects on left ventricular hypertrophy
A system-level computer simulation of chronic high sodium intake effects is conducted. The current model couples a cardiovascular hemodynamics model and a renal system model. Left ventricular (LV) wall stress is modeled to compute the changes of the LV wall thickness. Modeling results suggest high sodium intake alters the body-fluid homeostasis and increases the LV work load and relative wall thickness.
high sodium intake left ventricular hypertrophy cardiovascular hemodynamics renal system model mathematical modeling