Rapid construction of metabolic models for a family of Cyanobacteria using a multiple source annotation workflow
Cyanobacteria are photoautotrophic prokaryotes that exhibit robust growth under diverse environmental conditions with minimal nutritional requirements. They can use solar energy to convert CO2 and other reduced carbon sources into biofuels and chemical products. The genus Cyanothece includes unicellular nitrogen-fixing cyanobacteria that have been shown to offer high levels of hydrogen production and nitrogen fixation. The reconstruction of quality genome-scale metabolic models for organisms with limited annotation resources remains a challenging task.
metabolic modeling cyanobacteria cyanothece genome-scale metabolic model semi-automated metabolic network reconstruction