Corpuscular Antigenic Microarray for the Serodiagnosis of Blood CultureNegative Endocarditis
Blood culturenegative endocarditis is due to fastidious bacteria, including Coxiella burnetii and Bartonella spp. Diagnosis of such infection relies on serology and microimmunofluorescence is therefore the reference method. We developed a multiplex serology test featuring automatic incubation and reading and incorporating internal controls. Preliminary results indicate that this new serologic test is valuable for the rapid, automated serological diagnosis of blood culturenegative endocarditis
endocarditis multiplexed serology immunofluorescence diagnosis