CytoSpectre: a tool for spectral analysis of oriented structures on cellular and subcellular levels
Orientation and the degree of isotropy are important in many biological systems such as the sarcomeres of cardiomyocytes and other fibrillar structures of the cytoskeleton. Image based analysis of such structures is often limited to qualitative evaluation by human experts, hampering the throughput, repeatability and reliability of the analyses. Software tools are not readily available for this purpose and the existing methods typically rely at least partly on manual operation.
spectral analysis orientation isotropy cardiomyocytes fourier transform power spectrum image analysis microscopy artificial images stretching