NF-?B and Bcl-2 in Helicobacter pylori-Induced Apoptosis in Gastric Epithelial Cells
Helicobacter pylori (H. pylori) has been considered as an important pathogen of gastroduodenal inflammation and gastric carcinogenesis. However, the pathogenic mechanisms including H. pylori-induced apoptosis and subsequent molecular mechanisms have not been clarified yet. The present study examined the role of Bcl-2 and its relation to NF-?B in H. pylori-induced apoptosis in human gastric epithelial AGS cells. AGS cells were cultured in the presence of H. pylori, at a bacterium/cell ratio of 300
nf-?b bcl-2 helicobacter pylori apoptosis gastric epithelial cells