Is information about peptide sequence necessary in multivariate analysis?
If information about sequence is omitted, permutation of amino acids within a peptide can cause unwanted effects in multivariate analysis. This effect is readily apparent in principal component analysis, while it is less so in partial least squares analysis so that care must be exercised when interpreting the results. (C) 2001 Elsevier Science B.V. All rights reserved.
peptide sequence multivariate analysis amino acid