Phase computations and phase models for discrete molecular oscillators
Biochemical oscillators perform crucial functions in cells, e.g., they set up circadian clocks. The dynamical behavior of oscillators is best described and analyzed in terms of the scalar quantity, phase. A rigorous and useful definition for phase is based on the so-called isochrons of oscillators. Phase computation techniques for continuous oscillators that are based on isochrons have been used for characterizing the behavior of various types of oscillators under the influence of perturbations such as noise.
phase models discrete molecular oscillators isochrons noise oscillator phase phase noise numerical methods monte carlo methods stochastic simulation algorithm (ssa) phase equations phase computation schemes