Advances in the treatment of neurodegenerative disorders employing nanotechnology
Due to limitations posed by the restrictive bloodbrain barrier, conventional drug delivery systems do not provide adequate cyto-architecture restoration and connection patterns that are essential for functional recovery in neurodegenerative disorders (NDs). Nanotechnology employs engineered materials or devices that interact with biological systems at a molecular level and could revolutionize the treatment of NDs by stimulating, responding to, and interacting with target sites to induce physiological responses while minimizing side effects. This review provides a concise discussion of the current applications of nano-enabled drug-delivery systems for the treatment of NDs, in particular Alzheimer's and Parkinson's diseases, and explores the future applications of nanotechnology in clinical neuroscience to develop innovative therapeutic modalities for the treatment of NDs.
nanotechnology bloodbrain barrier drug delivery parkinson's disease neuroscience nanoscience neurobiology nanoparticles nanostructured nano-biotechnology engineered nanomaterials multifunctional nanoparticles polymers drug targeting site-specific alzheimer's disease