Huntington's disease
Autor: Raiane Paiva | Publicado: 2013-09-22T21:16:00-07:00


It is likely that among relatives , friends or acquaintances you've heard about or even seen neurological diseases such as Parkinson's , Alzheimer's , schizophrenia or other degenerative disease of the nervous system . When neurological disease attacks the nervous system affects cognitive ability , thinking of the individual , in the case of Alzheimer 's dementia developed due to the accumulation of proteins in the brain , responsible for the loss of connection between neurons and cell death that causes atrophy brain .

In this context , 20 years came to Huntington's disease , which is also neurological, presenting symptoms of cognitive decline attacking the nervous system , causing an inherited disorder in the brain , the person has agitated behavior sometimes seems to be dancing , gestures compulsive and difficult to perform simple tasks like hitting a key in a lock . The gene that science knows is 4p16.3 , located on chromosome 4 , it encodes a protein called huntingtin , which would be linked to the development and that all living beings possess , even amoebas . In the first part of the gene there is a sequence of three nucleotides (CAG) , which is repeated several times. Up to 26 repetitions nothing unusual happens . Between 27 and 39 , there is such a gray zone , which can cause Huntington in future generations. From 40 repetitions , the owner of the gene will express the disease at some point . For some unknown reason men go through more reps , adding symptoms of offspring , which may present the youth version .

Huntington's disease , it is a rare disease of Caucasian origin , there are few cases , therefore, in Africa and Asia . In Brazil , its incidence is 7 and 10 cases per 100 thousand , but in Feira Grande - Alagoas , the incidence is high , and 1 case each 1000mil , the subject is the relationship between marital uncles , nieces and cousins ​​, increasing probability of transmission to the descendant from 50% to 75%.

Unfortunately Huntington's disease has not yet found a cure , but we need to be receptive to treatments offered . Treating a disease does not mean cure , but rather to control symptoms and relieve suffering mainly due to the problem.

Huntington's disease is also known as Huntington's chorea or Chorea , which is his first name and means in Greek dancing .

There Syndenham of chorea , chorea minor or known as rheumatic chorea , is a key diagnostic indicators of rheumatic fever , it is estimated that 10 % to 40 % of children with this condition develop chorea . It predominantly affects children between 5 and 15 years , more frequently in females , with an incidence of approximately 0.5 to 2 cases per 100,000 inhabitants per year in the United States .

- Korea, derived from the Greek word that means dancing , consists of involuntary movements , sometimes at home , sometimes disrupting voluntary movement , arrhythmic , asymmetric , sudden , brief and pointless .

I provide the link with the video http://migre.me/gasyP illustrating a typical case of chorea Syndenham , for anyone interested in taking note of the symptoms of this disease .

Site global organization of Huntington disease&nbsp;http://www.hdsa.org/