LEUCEMIA
Autor: Clovis de Mattos | Publicado: 2010-08-03T18:01:00-03:00

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 <![endif]-->  LEUCEMIA Sinônimos: Câncer no sangue O que é? Leucemia é o câncer das células brancas do sangue, os leucócitos. Esta doença começa na medula óssea (parte interna dos grande ossos, a “fábrica do sangue”) e se espalha para outras partes do corpo. Há vários sub-tipos de leucócitos e, por isso, há diferentes tipos de leucemia. Normalmente, se divide nos dois principais grupos de células brancas: as leucemias linfocíticas ou leucemias mielóides. Além disso, pode se apresentar de duas formas, a forma aguda ou a forma crônica, dependendo da velocidade com que aparecem os sintomas e como ela evolui. Na forma aguda, as células são imaturas e não funcionam como deveriam, além de se reproduzirem muito rápido. Na forma crônica, as células são mais maduras e podem manter algumas das suas funções normais. O número de células malignas, neste último caso, aumenta vagarosamente. Este tipo de câncer é o câncer mais comum nas crianças, mas pode acometer adultos e velhos, também. Nos jovens, a forma mais comum é a leucemia linfocítica aguda, e nos adultos, a leucemia mielóide aguda seguida da leucemia linfocítica crônica. O que se pode sentir? Os sintomas da leucemia estão relacionados à piora do estado geral, porque o câncer é uma doença que compromete o corpo como um todo. Além disso, pode-se desenvolver sintomas relacionados à diminuição da atividade das células da medula óssea Sintomas gerais: 
&nbsp; 
         <!--[if !supportLists]-->a)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <!--[endif]-->Perda de   apetite  
         <!--[if !supportLists]-->b)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <!--[endif]-->Perda de   peso não planejada ou sem fazer dieta  
         <!--[if !supportLists]-->c)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <!--[endif]-->Aumento dos   gânglios (ínguas), fígado e baço  
         <!--[if !supportLists]-->d)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <!--[endif]-->Sensação de   gripe que dura muitos dias  
         <!--[if !supportLists]-->e)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <!--[endif]-->Dor nas   articulações (juntas) e ossos  
        
Sintomas relacionados à diminuição da atividade das células brancas (leucócitos), responsáveis pelo combate à infecções: 
&nbsp;
         Febre e calafrio  
         Infecções de repetição,   principalmente “infecções oportunistas”, como candidíase oral e do esôfago   (“sapinho”) ou pneumonia atípica  
Sintomas relacionados à diminuição da atividade das plaquetas, responsáveis pelo controle da coagulação: 
&nbsp; 
         Sangramento   e hematomas frequentes sem um trauma claro ou proporcional  
         Sangramento   das gengivas  
         Petéquias,   pequenas manchas vermelhas em baixo da pele  
Sintomas relacionados à diminuição da atividade das células vermelhas (hemáceas): 
&nbsp; 
         Anemia  
         Fraqueza  
Como esta doença é diagnosticada? A pessoas que suspeitam que podem ter alguma alteração do sangue, principalmente, se suspeitam que podem estar com algum tipo de leucemia, devem procurar um médico. Este fará uma história e um exame físico completo para procurar algum sintoma ou alteração que confirme a suspeita de leucemia. Além disso, um exame de sangue e alguns exames de imagem, como raio X e tomografia computadorizada, devem ser realizados para completar a avaliação da doença, o diagnóstico diferencial e a extensão do problema. Porém, somente uma biópsia da medula óssea e/ou uma biópsia de um gânglio é que dará o diagnóstico definitivo. Para alguns casos, poderá ser necessário, também, uma punção do líquor - líquido presente na medula espinhal (diferente da medula óssea). Qual é o tratamento para leucemia? A maioria das leucemias, independente do tipo e evolução, necessita de quimioterapia (medicamentos que destroem as células malignas). Estes medicamentos podem ser dados na veia e, neste caso, é necessário que o paciente seja atendido num centro médico especializado em câncer e/ou leucemia, ou por via oral, quando o paciente recebe o medicamento, mas o toma em casa. A quimioterapia pode ser dada sozinha ou, ainda, em combinação com outros tipos de tratamento, como: transplante de medula óssea, radioterapia, imunoterapia com interferon ou cirurgia. A decisão de qual é o tratamento mais adequado é baseada no tipo de leucemia, na idade e nas condições clínicas do paciente, além das características genéticas da lihagem de célula do sangue que está alterada. Como se previne esta doença? Muito pouco se sabe sobre como reduzir o risco de desenvolver leucemia, principalmente em crianças. Porém, vários fatores podem aumentar este risco, devendo ser evitados. No caso de não se poder evitá-los, como no caso de uma doença prévia, deve-se ficar atento a possíveis sintomas relacionados à leucemia, e procurar um médico experiente sempre que se tenha alguma dúvida. Fatores de risco associados às Leucemias: 
&nbsp; 
         <!--[if !supportLists]-->1)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <!--[endif]-->Cigarro e   outras formas de consumo de tabaco  
         <!--[if !supportLists]-->2)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <!--[endif]-->Produtos   químicos como benzeno  
         <!--[if !supportLists]-->3)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <!--[endif]-->Radioterapia   e quimioterapia prévias para outros tumores  
         <!--[if !supportLists]-->4)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <!--[endif]-->Terapias de   imunossupressão como as utilizadas após um transplante  
         <!--[if !supportLists]-->5)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <!--[endif]-->História   familiar de leucemia (principalmente para as crianças)  
         <!--[if !supportLists]-->6)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <!--[endif]-->Síndrome de   Down.  
Perguntas ao seu médico: Leucemia pode se transmitir pelo contato físico ou pelo sangue? Quais as chances de cura de leucemia em crianças e em adulto? A quimioterapia fará eu perder o cabelo? E se a doença voltar, existem outros tratamentos para fazer depois?