Neoplasia
Autor: Patoloblogger | Publicado: 2012-06-22T23:55:00-07:00

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São “Proliferações
locais de clones celulares cuja reprodução foge ao controle normal, e que
tendem para um tipo de crescimento autônomo e progressivo, e para a perda de
diferenciação.”



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Neoplasia
maligna



Produzem destruição local, a
destruição em locais distantes e geral, desordens metabólicas. Pode causar a
morte se não for tratada de forma adequada e oportuna. Elas são coletivamente chamadas
de câncer.


Características gerais

O crescimento rápido (semanas a
meses), não podem ser abundantes mitoses, necrose, e crescimento discordantes
entre parênquima e estroma. Malignidades cutâneas ou nas mucosas provoca
úlceras de necrose tumoral (tumores ulcerados).

Crescimento infiltrativo e
invasivo, destrutivo. Mal definidas, irregulares, de acordo com a resistência
relativa de vários tecidos de invasão: tecido conjuntivo frouxo e o lúmen dos
pequenos vasos linfáticos oferecer pouca resistência à invasão, a resistência
das paredes das artérias, ossos e cartilagens oferecer mais, mas também pode
ser invadido.



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Neoplasia
benigna 



Ocorrer apenas alterações locais,
geralmente de um mecânico. Nesta rara ocorrência de morte, embora dependendo de
fatores topográficos ou funcionais do próprio tumor, pode ser letal.

Exemplos: compressão do
meningioma cerebral, adenoma da paratireóide pela hipercalcemia.



Características gerais. 


Crescimento lento (meses ou anos). 
Crescimento expansivo 
Tumores arredondado, às vezes, encapsulados, bem demarcada. Elas podem
ser completamente removido cirurgicamente, sem reaparecer, ou nenhum retorno. 
Células típicas do tecido de que são originários, que está muito bem
células diferenciadas. 
Mitoses raras ou ausentes.