syedzayyan/paper_mill_benchmark huggingface dataset:
Effect of Music Therapy Combined with Free Position Delivery on Labor Pain and Birth Outcomes

At present, the clinical effect of music therapy combined with free position to assist delivery is rarely reported.Based on evidence-based nursing, this study is aimed at exploring the effect of the combination of music therapy and free position delivery on labor pain and maternal and fetal outcomes.Methods.A total of 440 primiparas with vaginal delivery in the department of obstetrics and gynecology of the first affiliated hospital of soochow university between july 2018 and july 2019 were selected.They were divided into music therapy, free position delivery group ( n = 201 ) and traditional delivery group ( n = 239 ).Subsequently, the two groups were compared in terms of the chinese perception of labor pain questionnaire (plpq) score, bleeding amount at 2 hours after birth, perineal injury, labor stage duration, and 1 minute apgar score.Results.The combination group had better results of the chinese plpq score, postpartum hemorrhage, and perineum condition.However, compared with traditional delivery, a longer duration of the first stage and total stage of labor was found in the combination group.Music therapy combined with free position delivery required less medical intervention during delivery, and there was no significant difference in 1 minute apgar score between the two groups.Conclusions.Music therapy combined with free position delivery, an intervention based on evidence-based nursing, can effectively reduce maternal labor pain, postpartum hemorrhage, soft birth canal injury, and medical intervention during labor.It is, therefore, a safe intervention to assist delivery.

Journal: Applied Bionics and Biomechanics (2022)
Publication types: Clinical Study;
Effect of MTHFRC677 T Gene Polymorphism on Early Morning Blood Pressure in Elderly Female Patients with H-Type Hypertension

The distribution characteristics of methylenetetrahydrofolate reductase (mthfr) gene c677 t polymorphism and its influence on early morning blood pressure in elderly female patients with h‐type hypertension are investigated.A total of 220 elderly female patients with hypertension who received diagnosis and treatment in our hospital from march to september 2021 are selected.All patients received serum index detection in our hospital and are grouped according to blood homocysteine (hcy) level.Patients with hcy&gt;10 μ mol/l are classified as h‐type hypertension and included in h‐type hypertension group ( n = 166).Patients with hcy≤10 μ mol/l are included in the non‐h‐type hypertension group ( n = 54).Both groups underwent 24‐hour ambulatory blood pressure monitoring.Base frequency and allele distribution of mthfr gene c677 t locus are compared between the two groups, and the relationship between different bases of mthfr gene c677 t locus and morning blood pressure and hcy level is analyzed.The risk factors of morning hypertension in patients with h‐type hypertension are analyzed by binary logistic regression.Binary logistic regression analysis shows that smoking history, drinking history, high‐salt diet, mthfr gene c677 t genotype, and abnormal 24 h systolic blood pressure are the risk factors for the occurrence of morning hypertension in h‐type hypertension patients.The frequency of tt homozygous mutation at the c677 t site of the mthfr gene is high in patients with h‐type hypertension, and the mutation of the c677 t site of the mthfr gene had an effect on systolic blood pressure and hcy level.

Journal: Contrast Media & Molecular Imaging (2022)
Publication types: Research Article;
Effect of Medical Image Fusion in the Treatment of Poststroke Limb Dysfunction with Acupuncture and Moxibustion of Traditional Chinese Medicine

According to relevant data, the morbidity and mortality of strokes in china remain high.Without effective treatment, stroke morbidity and mortality will continue to rise, which may become the second leading disease in the world.With the nonstop advancement and improvement of clinical innovation in china, the death pace of stroke patients has dropped altogether.After clinical treatment, the patient actually showed a progression of sequelae, which made it challenging to work on the personal satisfaction of the patient.The purpose for this paper was to concentrate on the impact of medical image fusion in the treatment of poststroke appendage brokenness with tcm needle therapy.The related concepts of medical image fusion and the meaning of acupuncture and moxibustion in traditional chinese medicine, stroke, and limb dysfunction were introduced.In this study, acupuncture and moxibustion were analyzed to explore the therapeutic effect of this type of therapy on upper extremity dysfunction caused by phlegm and blood stasis blocking collaterals and to provide a scientific method for the treatment and efficacy judgment of upper extremity motor dysfunction after stroke.Before the treatment measures were taken, there was no significant difference in the general data and all index scores between the two groups ( p &gt; 0.05), and there was no significant difference in the baseline data, reflecting high balance and comparability.In the following 3 months of treatment, the fma score, nihss score, bi list, and vas score of the two groups of patients were essentially not quite the same as those before treatment ( p &lt; 0.05).When treatment, there was a huge contrast between the trial group and the control group ( p &lt; 0.05).The finish of the trial in this paper is that needle therapy joined with pricking and measuring can essentially work on the engine capability of stroke patients with furthest point brokenness brought about by mucus and blood balance impeding securities.

Journal: BioMed Research International (2022)
Publication types: Research Article;
Effect of Intervention of Probiotics in Advance on Treg/Th17 in Premature Mice

To preliminarily understand the differentiation characteristics of regulatory t cells (tregs) and th17 at a different time in preterm mice, the impacts of probiotics on immune function progression, as well as the correlation of probiotics with tregs and th17.On embryonic day 18 of gestation, a mouse model of preterm birth was built using mifepristone (ru486).Following ipi of ru486, newborn mice were randomized to probiotics or ns gavage administration.Full‐term newborn mice were given the same dose of ns gavage administration.Phenotypic analysis of peripheral immune cell frequency was performed using flow cytometry.Cytokine measurements were phenotyped by enzyme‐linked immunosorbent assays.On the 14th and 21st days after birth, the highest and lowest expressions of foxp3, the treg transcription factor, were observed in full‐term mice and premature mice by ns gavage administration, respectively, while the opposite trend was found in the th17 transcription factor il‐17.il‐2, il‐6, and tgf‐ β rose with age but showed different trends among the three groups.Il‐2 is the highest in full‐term mice and the lowest in premature mice.Il‐6 and tgf‐ β is the lowest in full‐term mice and the highest in premature mice.Probiotics are beneficial to the development and maturation of the immune system, which may play a role in regulating the ratio of treg/th17.Probiotic preintervention can effectively promote the differentiation of treg and inhibit the differentiation of th17 in premature mice.Its mechanism of action may play a biological role by regulating cytokine (il‐2, il‐6, and tgf‐ β ) secretions.

Journal: BioMed Research International (2022)
Publication types: Research Article;
Effect of Endoscopic Retrograde Cholangiopancreatography Lithotomy Combined with Laparoscopic Cholecystectomy on Pain and Prognosis of Patients with Gallstones and Extrahepatic Bile Duct Stones

The researchers aim to assess how endoscopic retrograde cholangiopancreatography lithotomy and laparoscopic cholecystectomy affected pain and prognosis in individuals with gallstones and extrahepatic bile duct stones.Methods.Researchers studied 100 persons with gallstones and extrahepatic bile duct stones from january 2016 to august 2021.They were split into two groups: control and observation.The control group underwent open cholecystectomy + choledocholithotomy + t-tube drainage.There were ercp + lithotomy + laparoscopic cholecystectomy procedures conducted on the observation group of patients (lc).The operation time, incision size, and bleeding volume; stone clearance rate and stone recurrence rate; visual analogue scale (vas); eating time, exhaust time, out of bed activity time, and postoperative hospital stay; the two groups’ difficulties were contrasted and studied.Results.The observation group’s operation duration was much longer than the control group’s, and the incision size and bleeding volume were significantly reduced in the observation group.When it came to recurrence, there was a significant difference between the observation group (2.0%) and the control group (4.0%), even though stone clearance did not differ substantially (20.00%).The vas scores 3 and 7 days after surgery were significantly different between the observation and control groups.The observation group’s eating time, exhaustion, activity time, and postoperative hospital stay were much shorter than the control group’s; complications occurred at a lower rate (20%) in the observation group than in the control group (34%).Conclusion.When gallstones and extrahepatic bile-duct stones are removed using laparoscopic lithotomy and laparoscopic cystoscopy (lc), the operation indices are improved and the risk of recurrence of stones is reduced and reducing the occurrence of complications, all of which improve patient outcomes and deserve to be considered a clinical reference.

Journal: Computational Intelligence and Neuroscience (2022)
Publication types: Clinical Study;
Effect of Early Rehabilitation and Nursing Intervention on the Rehabilitation Prognosis of Elderly Stroke Hemiplegia Patients in the Department of Neurology

To explore the influence of rehabilitation outcomes in older patients with stroke hemiplegia from the neurology department by early rehabilitation nursing.Methods.70 cases of old patients with stroke hemiplegia from 2020/01 to 2021/01 were randomly divided into observation group (35 cases) and control group (35 cases).The control group was nursed by usual care.The observation group was nursed by early rehabilitation nursing.Nursing efficacy was observed.Results.The scores of active demand, resistance, and rehabilitation nursing cooperation degree after the nursing for the observation group were higher than the control group ( p &lt; 005 ).The score of nihss after the nursing for the observation group was lower than that for the control group ( p &lt; 005 ).The scores of bi, bbs, and fugl-meyer after the nursing for the observation group were higher than those for the control group ( p &lt; 005 ).The total rate of nursing satisfaction for the observation group was higher than the control group ( p &lt; 005 ).Conclusion.Early rehabilitation nursing can improve rehabilitation initiatives, rehabilitation outcomes, and nursing satisfaction in older patients with stroke hemiplegia from the neurology department.

Journal: Applied Bionics and Biomechanics (2022)
Publication types: Clinical Study;
Effect of Dihydroquercetin on Energy Metabolism in LPS-Induced Inflammatory Mice

This study investigated the effects and alterations of dihydroquercetin on the growth performance, nutriment metabolism, antioxidant and immune function, and energy substrate utilization in lipopolysaccharide‐challenged mice.A total of 0, 50, and 200 mg/kg of dihydroquercetin were intragastrically administered once a day for 21 days.After the pretreatment with dihydroquercetin, each group was subjected to a lipopolysaccharide challenge (except for the control group).After lipopolysaccharide injection, food intake, body weight, metabolic indexes of blood and liver nutrients, blood inflammatory factors, and liver oxidative stress indexes were measured at 6, 12, 24, and 48 h, respectively.Indirect calorimetry analysis was performed by respiratory gas analysis for 48 h to calculate the energy substrate metabolism of carbohydrate, fat, and protein.Urinary nitrogen excretion was measured to evaluate the urinary protein metabolism to calculate the substrate utilization.The results showed that dihydroquercetin pretreatment can significantly increase the weight gain and average food intake and decrease the mortality rate in lipopolysaccharide‐induced inflammation mice.Furthermore, dihydroquercetin pretreatment can alleviate the negative effects of lipopolysaccharides by increasing levels of superoxide dismutase and glutathione peroxidase and by decreasing the malondialdehyde and serum inflammatory cytokines (interleukin‐1 β , nuclear factor κ b, and interleukin‐6).Dihydroquercetin pretreatment also can relieve nutrient metabolic disorder by increasing blood glucose, serum total protein, and liver glycogen levels and reducing serum and liver triglycerides, serum cholesterol, serum lactate dehydrogenase, and serum urea nitrogen levels.Meanwhile, it increases the relative utilization of carbohydrate, reducing relative utilization of protein and lipid, alleviating the change in energy metabolism pattern from glucose‐predominant to lipid‐predominant caused by lipopolysaccharide stimulation.In addition, the degree of metabolic pattern transformation depends on the dose of dihydroquercetin supplement.Finally, according to principal component analysis, we found that the inflammation was strongest in the mice at 24 h and was subsequently relieved in the lps‐stimulated group, whereas in the dihydroquercetin‐pretreated group, the inflammation was initially relieved.To summarize, dihydroquercetin pretreatment can improve energy metabolism disorder and attenuate the negative effects of lipopolysaccharide challenge in mice from the initial stage of inflammation.

Journal: BioMed Research International (2022)
Publication types: Research Article;
Effect of Core Stability Training on Unstable Support Surfaces in Postoperative Rehabilitation of Thoracolumbar Vertebral Compression Fractures in the Elderly

Thoracolumbar vertebral compression fractures (tvcf) are caused by anterior flexion or vertical downward violence to the spine (sezer et al.2021).This study is aimed at investigating the effect of core stability training (cst) on unstable support surfaces in the postoperative rehabilitation of tvcf in the elderly.Methods.Ninety-eight patients with tvcf who underwent surgical treatment in our hospital from july 2021 to april 2022 were selected as study subjects.Then, they were divided into a research group receiving unstable support surface cst and a control group with conventional rehabilitation training according to the random number table method.Before and after the training, the x-ray machine was positioned and the anterior margin and middle height ratio and the posterior convex cobb angle of the injured vertebrae were observed, and the balance detector was used to detect patients’ eye opening and closing trajectory length, romberg rate, and to perform gait test.Patients’ pain, lumbar spine function, and quality of life were subsequently assessed using the visual analogue scale (vas), oswestry dysfunction index (odi), generic quality of life inventory-74 (gqol-74), and patient satisfaction with rehabilitation was investigated.Results.After rehabilitation training, there was no statistically marked difference in eye-opening trajectory length between both groups ( p &gt; 0.05 ).The research group had higher scores than the control group in all dimensions of the anterior border of the injured vertebra, middle height ratio, and gqol-74, while the posterior convex cobb angle, closed-eye trajectory length, romberg rate, vas, and odi were lower than the control group ( p &lt; 0.05 ).The research group also revealed better gait improvement and higher rehabilitation satisfaction than the control group after training ( p &lt; 0.05 ).Conclusion.Unstable support surface cst can effectively improve postoperative vertebral body rehabilitation, balance function, gait, pain conditions, and lumbar spine function in elderly tvcf patients, and enhance their quality of life and rehabilitation satisfaction.This trial is registered with chi ctr2000014547.

Journal: Computational and Mathematical Methods in Medicine (2022)
Publication types: Clinical Study;
Effect of Chinese Traditional Wushu on Cancer-Related Fatigue, Sleep Quality and Upper Limb Dysfunction of Breast Cancer Survivors: A Systematic Review and Meta-Analysis

This study is aimed at evaluating the effect of chinese traditional wushu (ctw) on cancer‐related fatigue (crf), sleep quality, and upper limb dysfunction.Data sources .We searched studies containing randomized controlled trials up to july 2021 in pub med, embase, web of science, china national knowledge infrastructure (cnki), wanfang database, and china biological medicine on this topic.Methods .A randomized controlled trial of ctw on major outcome indicators such as crf, sleep quality, and upper limb dysfunction of breast cancer survivors.Study screening, data extraction, and risk of bias assessment were performed independently by two reviewers.Meta‐analysis was conducted with stata 16.0 software.The quality of the evidence was assessed by the cochrane collaboration risk of bias (rob2.0).Results .Eighteen studies met the requirements for meta‐analysis ( n = 1331).We found that ctw has no obvious effect on improving breast cancer survivors’ crf (smd = −0.733; p = 0.059; i 2 = 89.3%), but it can effectively improve their sleep quality (wmd = −2.266; p = 0.022; i 2 = 99.2%) and upper limb dysfunction (smd = 1.262; p ≤ 0.001; i 2 = 88.5%).Conclusion .Although more studies on this topic are needed to prove the effectiveness of this method, the results of our review show that ctw is significantly helpful for better sleep and upper limb dysfunction.But the effects on crf will need to be confirmed further.Implications for cancer survivors .In the future intervention process, to verify the effectiveness of ctw on improving crf for breast cancer survivors, it would be suggested to pay close attention to breast cancer survivors’ response to exercise, achieve regular follow‐up, strictly conduct the intervention scheme on the premise of ensuring absolute security, and reduce the loss of intervention objects.

Journal: BioMed Research International (2022)
Publication types: Meta-Analysis;Review Article;
Effect of Application of Repeated Downhill Walking Bouts on Ankle Isokinetic Parameters in Children with Obesity

Obesity among children became of high concern.Obesity can affect many health aspects including muscular strength.Downhill walking is a useful intervention to enhance muscular strength, especially in older adults.Objective.The current study’s purpose was to investigate the effect of repeated bouts of downhill walking on ankle isokinetic parameters in children with obesity.Methods.32 obese male children aged from 8 to 12 years engaged in the study.The children were divided into two groups: the level walking group (lwg) ( n = 16 ) and the downhill walking group (dwg) ( n = 16 ).Participants in both groups walked 20 minutes on the treadmill, two sessions per week for 6 weeks, with a speed of 5 km/h, and the treadmill slope used for the dwg was set at –20%.Isokinetic dynamometry (cybex 6000) was used to analyze the normalized eccentric and concentric torque of both ankle dorsiflexors and plantar flexors of the dominant leg in all participants.Results.The normalized peak torques for eccentric plantar flexion, concentric plantar flexion, eccentric dorsiflexion, and concentric dorsiflexion significantly increased by 38.66%, 23.87%, 38.58%, and 15.51%, respectively, after repeated bouts of downhill walking.Level walking resulted in nonsignificant improvement in the muscular torques.Conclusion.Downhill walking is a beneficial intervention in improving ankle muscular torques of obese children.

Journal: Applied Bionics and Biomechanics (2022)
Publication types: Research Article;
Effect of Application of Different Exercise Intensities on Vitamin D and Parathormone in Children with Down’s Syndrome

Children with down’s syndrome are more liable to vitamin d deficiency.Treating this deficiency with supplements is associated with the risk of intoxication.Aim.The study is aimed at comparing the effect of two exercise intensities on the modulation of vitamin d and parathormone levels in children with ds.Methods.Forty-four ds male children aged from 8 to 12 years participated in the study.They were assigned randomly into two equal groups.Group i received high-intensity treadmill aerobic exercises, and group ii received moderate-intensity t-ae, three times per week for three months.The blood samples were collected from both groups before the intervention, after one month of intervention, then after three months of intervention to assess serum 25(oh)d and pth levels.Results.Repeated measure manova revealed that the high-intensity t-ae induced a significant increase in 25(oh)d after one month and after three months while it significantly decreased pth only after three months.Moderate-intensity t-ae had a nonsignificant effect on both hormones.Conclusion.The current study concluded that the high-intensity t-ae improved both vitamin d and parathormone serum levels after three months of intervention.

Journal: Applied Bionics and Biomechanics (2021)
Publication types: Clinical Study;
Effect of Ankle Proprioception Training on Preventing Ankle Injury of Martial Arts Athletes

Martial arts routines originated in china and are a traditional sport of the chinese nation.They are one of the outstanding sports culture representatives in china since ancient times.Excessively difficult movements in some martial arts routines during competitions or training can cause athlete injuries.The purpose of this article is to study the effect of proprioceptive training of ankle joints on preventing ankle injuries in martial arts athletes.Can ankle strength training and ankle proprioceptive training combined with strength training improve the dynamic and static balance of football players?This article analyzes the mechanism and causes of martial arts athletes’ injuries and proposes treatment methods for ankle injuries.In the experimental part of this article, 16 martial arts athletes (8 males and 8 females) were selected as research objects, and they were randomly divided into 4 male and female experimental groups and 4 control groups.The experimental group received ankle muscle strength training for 6 weeks, and the control group received ankle muscle strength training and ankle proprioception training.The experimental results prove that ankle proprioceptive training can improve the dynamic and static balance of martial arts athletes and can effectively prevent the occurrence of ankle injury.In this paper, the dynamic balance ability in the biped standing state with eyes closed was tested, and the reductions of the stability index in the front and back directions of the control group and the experimental group were 0.03 and 0.2, respectively.It can be seen that the stability training effect of the experimental group was obvious.

Journal: BioMed Research International (2022)
Publication types: Clinical Study;