syedzayyan/paper_mill_benchmark huggingface dataset:
Effect of Hematocrit Injury on the Survival Rate of Advanced Malignant Tumors and Its Clinical Significance

To investigate the effect of logistic multivariate analysis on the survival rate of advanced malignant tumors and to evaluate the effect of erythrocyte storage injury on the survival rate of advanced malignant tumors and its clinical significance.Methods.A retrospective analysis was performed on 120 advanced cancer patients who received blood transfusion in shaanxi cancer hospital from march 2018 to june 2019, and the risk factors for death were analyzed.A total of 72 advanced cancer patients admitted to hospital from march 2019 to june 2021 were included in the study.The patients with red blood cell transfusion storage time ≤ 14 d were the study group ( n = 36 ), and the patients with red blood cell transfusion storage time &gt; 14 d were the control group ( n = 36 ).Compare the total efficiency of blood transfusion.The levels of hb, erythrocyte count, hematocrit (hct), blood oxygen saturation (spo2), creatinine (cr), erythrocyte deformability index, whole blood, erythrocyte, and hemoglobin before and after blood transfusion were compared, and the adverse reactions of blood transfusion were recorded.Results.Dyspnea and delirium were significantly associated with patient survival time ( p &lt; 0.05 ).Red blood cell storage time ≤ 14 days, lym % &lt; 12 % , lactate dehydrogenase ldh &gt; 500 u/l, and alb &lt; 30 g/l were significantly correlated with survival time.Karnofsky performance status kps &lt; 30 , delirium, ldh &gt; 500 u/l, and albumin alb &lt; 30 g/l were independent influencing factors of survival ( p &lt; 0.05 ).The overall effective rate of the research group was higher ( p &lt; 0.05 ).The incidence of adverse reactions in the study group was lower ( p &lt; 0.05 ).The levels of hb, red blood cell count, and hct in the study group were higher ( p &lt; 0.05 ).Compared with the control group, the spo2 level and the red blood cell deformability index were higher in the study group ( p &lt; 0.05 ).After blood transfusion, the level of (diphosphoglycerate) dpg in the study group was higher than that in the control group ( p &lt; 0.05 ).The length of hospital stay in the study group was significantly shortened ( p &lt; 0.05 ).The nosocomial infection rate and case fatality rate in the study group were significantly reduced ( p &lt; 0.05 ).Conclusion.Red blood cell storage time ≤ 14 d, lym % &lt; 12 % , ldh &gt; 500 u/l, and alb &lt; 30 g/l are all significantly correlated with survival time.Kps &lt; 30 , delirium, ldh &gt; 500 u/l, and alb &lt; 30 g/l were independent factors for survival ( p &lt; 0.05 ).Transfusion of red blood cells stored for ≤14 days in patients with advanced malignant tumors can significantly increase the effective infusion rate, improve anemia status, shorten hospital stay, and reduce mortality and risk of nosocomial infection and is worthy of clinical promotion.

Journal: Computational and Mathematical Methods in Medicine (2022)
Publication types: Research Article;
Effect of Enteral and Parenteral Nutrition Support on Pulmonary Function in Elderly Patients with Chronic Obstructive Pulmonary Disease Complicated by Respiratory Failure

To investigate the effect of enteral and parenteral nutrition support (epns) on pulmonary function in elderly patients with chronic obstructive pulmonary disease (copd) complicated by respiratory failure (rf).Methods.A total of 127 patients who underwent treatment for elderly patients with copd complicated by rf in our hospital from february 2020 to may 2022 were collected for a retrospective analysis.There were 41 patients with enteral nutrition support (group a), 46 with parenteral nutrition support (group b), and 40 with epns (group c).The levels of serum albumin (alb), prealbumin (pa), serum hemoglobin (hb), and serum transferrin (trf) were measured before and after nutritional support in the three groups, and the changes in pulmonary function of patients were compared.The changes in the levels of inflammatory factors and markers of oxidative stress (os) in serum were also detected, and the incidence of adverse reactions and length of stay (los) were counted.Results.Alb, pa, hb, and trf levels were increased in all 3 groups after nutritional support, with the highest in group c ( p &lt; 0.05 ).Similarly, lung function was improved in all 3 groups and inflammatory factor levels and os were suppressed, also most dramatically in group c ( p &lt; 0.05 ).There was no difference in the incidence of adverse reactions among the 3 groups, and the los in group c was shorter than those in groups a and b ( p &lt; 0.05 ).Conclusion.Epns can effectively improve the lung function of patients with copd combined with rf and reduce the inflammation and os damage.It can effectively improve the therapeutic effect of patients and has great application prospects in the treatment of copd combined with rh in the future.

Journal: Computational and Mathematical Methods in Medicine (2022)
Publication types: Research Article;
Effect of Comprehensive Rehabilitation Training Program in Orthopedic Nursing of Patients with Residual Limb Injury Caused by Crush

This study was developed to explore the role and application value of a comprehensive rehabilitation training (crt) program based on the remote monitoring system of limb rehabilitation training (lrt-rm system) in the rehabilitation nursing of patients with residual limb injuries caused by crush.The lrt-rm system was constructed based on the characteristics of limb movement and using the time-domain analysis method and support vector machine (svm).The 84 crush injury patients were selected as the research objects and divided into a control group (con group, received conventional rehabilitation therapy) and a crt group (received conventional rehabilitation therapy + functional training) according to different therapies, with 42 people in each group.The incidence of compound injuries and the incidence of residual limb injuries were counted and compared for patients in two groups.The differences in renal function, blood electrolytes, and biochemical indicators before and after treatment were analyzed.The mos 36-item short-form health survey (sf-36) scale was selected to evaluate the improvement of physical and mental health of the patients before treatment and 1 month (time point (tp1)), 3 months (tp2), 6 months (tp3), and 12 months (tp4) after the treatment.It was found that, after the intervention, the values of serum creatinine (scr), blood urea nitrogen (bun), uric acid (ua), k+, p3+, and white blood cells (wbc) of patients in crt group were obviously lower than those of con group ( p &lt; 0.05), and the values of carbon dioxide combining power (co2cp), ca2+, hemoglobin (hb), red blood cell (rbc), total protein (tp), and albumin (alb) were obviously higher than the values in con group ( p &lt; 0.05).In the crt group, the residual limb injury rate was lower in elbow, wrist, shoulder joint, ankle joint, and toe ( p &lt; 0.05) and extremely lower in knee joint in contrast to that in the con group ( p &lt; 0.001).The score of sf-36 was dramatically higher than that in the con group ( p &lt; 0.05).It suggested that the crt program based on the lrt-rm system was helpful for the rehabilitation of patients with crush injuries, and it can reduce the incidence of residual limb injuries in patients.Results of this study could provide a reference basis for the treatment of residual limb injuries caused by crush.

Journal: Journal of Healthcare Engineering (2022)
Publication types: Research Article;
Effect of Comprehensive Nursing Approach in Perioperative Stage of Patients with Hepatocellular Carcinoma Interventional Therapy

To examine the efficacy of a complete nursing strategy during the perioperative phase for patients undergoing interventional treatment for hepatocellular cancer.Methods.Sixty patients who were diagnosed with liver cancer and underwent interventional therapy in our hospital between february 2019 and december 2021 were recruited in this trial.All study subjects were numbered according to the time when the patients first came to our hospital, and were equally divided into a comprehensive group and a conventional group based on the odd and even number of the last number, with 30 cases in each group.Those in the conventional group received conventional nursing care, whereas patients in the comprehensive group received comprehensive nursing care.Before and after the nursing intervention, the quality of life, pain, and patient satisfaction in both groups were compared.Results.The quality of survival scores, including physical, emotional, role, social, and cognitive function scores of patients in the comprehensive group, were significantly higher than those in the conventional group ( p &lt; 0.05 ); there was no statistically significant difference in numeric rating scales (nrs) scores between the two groups compared before treatment ( p &gt; 0.05 ).After treatment, the nrs scores of patients in the study group were significantly lower than those of patients in the control group ( p &lt; 0.05 ); before the intervention, the difference between the emotional state scores of patients in the two groups was not significant and not statistically significant ( p &gt; 0.05 ), while the emotional state of patients in both groups improved after the intervention, and the self-rating anxiety scale (sas) and the self-rating depression scale (sds) scores of patients in the comprehensive group were lower than those in the conventional group ( p &lt; 0.05 ); the total incidence of adverse reactions in the comprehensive group (10.00%) was significantly lower than that in the conventional group (46.67%) ( p &lt; 0.05 ); and the total satisfaction of patients in the comprehensive group (93.33%) was significantly higher than that of patients in the conventional group (73.33%) ( p &lt; 0.05 ).Conclusion.The intervention of a comprehensive nursing approach in the perioperative period for patients with liver cancer is remarkable as it can relieve patients' psychological burden and pain, ensure a smooth operation, improve patients' postoperative quality of life, and also help to reduce the risk of postoperative adverse reactions, effectively enhancing patients’ satisfaction, and thus deserves to be promoted in clinical practice.

Journal: Evidence-Based Complementary and Alternative Medicine (2022)
Publication types: Clinical Study;
Effect of Calcification Based on Computer-Aided System on CT-Fractional Flow Reserve in Diagnosis of Coronary Artery Lesion

This study was to analyze the diagnostic value of coronary computed tomography angiography (ccta) and fractional flow reserve (ffr) based on computer-aided diagnosis (cad) system for coronary lesions and the possible impact of calcification.80 patients who underwent ccta and ffr examination in hospital were selected as the subjects.The ffr value of 0.8 was used as the dividing line and divided into the ischemic group ( ffr ≤ 0.8 ) and nonischemic group ( ffr &gt; 0.8 ).The basic data and imaging characteristics of patients were analyzed.The maximum diameter stenosis rate (mds %), maximum area stenosis rate (mas %), and napkin ring sign (nrs) in the ischemic group were significantly lower than those in the nonischemic group ( p &lt; 0.05 ).Remodeling index (ri) and eccentric index (ei) compared with the nonischemic group had no significant difference ( p &gt; 0.05 ).The total plaque volume (tpv), total plaque burden (tpb), calcified plaque volume (cpv), lipid plaque volume (lpv), and lipid plaque burden (lpb) in the ischemic group were significantly different from those in the non-ischemic group ( p &lt; 0.05 ).Mas % had the largest area under curve (auc) for the diagnosis of coronary myocardial ischemia (0.74), followed by mds % (0.69) and lpv (0.68).Ct-ffr had high diagnostic sensitivity, specificity, accuracy, truncation value, and auc area data for patients in the ischemic group and nonischemic group.The diagnostic sensitivity, specificity, accuracy, cutoff value, and auc area data of ct-ffr were higher in the ischemic group (89.93%, 92.07%, 95.84%, 60.51%, 0.932) and nonischemic group (93.75%, 90.88%, 96.24%, 58.22%, 0.944), but there were no significant differences between the two groups ( p &gt; 0.05 ).In summary, ct-ffr based on cad system has high accuracy in evaluating myocardial ischemia caused by coronary artery stenosis, and within a certain range of calcification scores, calcification does not affect the diagnostic accuracy of ct-ffr.

Journal: Computational and Mathematical Methods in Medicine (2022)
Publication types: Research Article;
Effectiveness Analysis of Entrepreneurial Method with Computer Data Simulation

Entrepreneurship has permeated all parts of society as a result of society’s development.College students are the main force of today’s entrepreneurship, and this work takes college students as the object of research.College students should focus not only on quantity but also on quality.In recent years, college students have engaged in a greater number of entrepreneurial activities, although their efficacy and influence have been limited.To improve the effectiveness of college students’ entrepreneurial methods, it is necessary to analyze their entrepreneurial methods to evaluate their effectiveness for method.This work presents a neural network for evaluating the efficacy of entrepreneurial strategies and employs computer data simulation technologies to validate effectiveness using a neural network and computer data simulation.First, using characteristics of global optimization of particle swarm optimization (pso), a dynamic domain population model is proposed to improve it.The new model is with a k-means clustering algorithm and aims to increase the diversity of the population.The enhanced pso (kpso) algorithm has a better global optimization ability, thus particles are less likely to fall into local extreme values.Second, maintain consistency between the particle dimension size in kpso and the weights and thresholds in the bp network and create a mapping link between kpso and the weights and thresholds.After determining the topology for the neural network, the improved bp network (kpso-bp) is utilized to analyze the effectiveness of college students’ entrepreneurial methods.Third, the computer data simulation results verify the effectiveness and correctness of the proposed method.

Journal: Security and Communication Networks (2022)
Publication types: Research Article;
Effect of Autologous Stem Cell Transplantation Combined with Modified VTD Regimen on Elderly Patients with Multiple Myeloma and Its Influence on miRNA Cytokines

To explore the effect of autologous stem cell transplantation combined with modified vtd regimen on elderly patients with multiple myeloma and its influence on mi rna cytokines.Methods.The data of 42 elderly patients with multiple myeloma who were treated in our hospital from may 2010 to june 2018 were retrospectively analyzed, and they were divided into the combined group (autologous stem cell transplantation combined with improved vtd scheme, n = 25 ) and the control group (improved vtd scheme, n = 17 ) according to different treatment schemes, and the clinical efficacy of the two groups was compared.The levels of cd3+, cd4+, cd4+/cd8+, and treg were measured in the two groups.The expression levels of mi rna-15a, mi rna-16, and mi rna-21 in the bone marrow fluid of the two groups were measured before and after treatment.The levels of m protein and myeloma cells in the two groups were detected.Comparing the incidence of adverse reactions between the two groups, the kaplan-meier method was used for survival analysis.Results.The total effective rate of the combined group (84.00%) was higher than that of the control group (52.94%), and the difference was statistically significant ( p &lt; 0.05 ).After treatment, the levels of cd3+, cd4+, cd4+/cd8+, treg, mi rna-15a, and mi rna-16 in the combined group were higher than those in the control group, and the levels of mi rna-21, m protein, and myeloma cells were lower than those in the control group, with statistical significance ( p &lt; 0.05 ).There was no significant difference in adverse reactions between the two groups ( p &gt; 0.05 ).The first, second, and third year survival rates of group a (96.00%, 88.00%, and 80.00%) were significantly higher than those of the control group (70.59%, 58.82%, and 47.06%), and the difference was statistically significant ( p &lt; 0.05 ).Conclusion.Autologous stem cell transplantation combined with a modified vtd regimen can effectively improve the immune function and survival rate of elderly patients with multiple myeloma, which is safe and effective.

Journal: Computational and Mathematical Methods in Medicine (2022)
Publication types: Research Article;
Entrepreneurship, Digital Capabilities, and Sustainable Business Model Innovation: A Case Study

Sustainable business model innovation can effectively cope with the complex and changing external environment in the digital economy, which is the key for enterprises to gain sustainable competitive advantage, and entrepreneurship is closely related to sustainable business models.However, the process and mechanism of the role of entrepreneurship on sustainable business model innovation are not clear in existing studies.The purpose of this article is to illustrate how entrepreneurship leads to and influences sustainable business model innovation.Based on the perspective of digital capabilities, this article adopts an exploratory single-case study to explore the new connotation of entrepreneurship and its influence mechanism on sustainable business model innovation.The study found that innovation spirit, adventure spirit, and co-benefit entrepreneurship have emerged in the digital economy.Through the inherent role of digital sensing capabilities, digital seizing capabilities, and digital transformation capabilities, sustainable business model innovation is effectively designed and implemented to achieve multidimensional value creation and capture.This article adds to the latest literature on sustainable business model innovation for enterprises through case evidence.

Journal: Mobile Information Systems (2022)
Publication types: Research Article;
Effect of Acupuncture and Rehabilitation Therapy on the Recovery of Neurological Function and Prognosis of Stroke Patients

Stroke is a common cerebrovascular disease among the middle-aged and elderly, which can lead to a series of neurological disorders.Acupuncture is an important part of traditional chinese medicine, with great value in improving the neurological deficits of stroke patients.In addition, rehabilitation therapy is also of great significance for alleviating the neurological deficits of patients and improving their activities of daily living.Objective.To explore the effect of acupuncture and moxibustion combined with rehabilitation therapy on the recovery of neurological function and prognosis of stroke patients.Methods.The case data of 100 stroke patients treated in the wuhan hospital of traditional chinese medicine from january 2019 to july 2021 were analyzed retrospectively.According to the treatment plan patients received, they were divided into the following two groups: an observation group ( n = 52 ) treated with acupuncture combined with rehabilitation therapy and a control group ( n = 48 ) treated with rehabilitation therapy alone.The two groups were compared in terms of the following items: therapeutic efficacy, plasma levels of cortisol (cor) and neuropeptide y (npy), nerve function, motor function, balance ability, self-care ability, swallowing function, negative emotions, and quality of life.Results.The therapeutic effect of the observation group was significantly higher than that of the control group ( p &lt; 0.05 ).The levels of cor and npy, as well as the neurological function, motor function, balance ability, self-care ability, swallowing function, and negative emotions, were not significantly different between the two groups before treatment ( p &gt; 0.05 ).While after intervention, all the above indexes improved in both groups, with better improvements in the observation group compared with the control group ( p &lt; 0.05 ).And the various dimensions concerning the quality of life of patients were also significantly better in the observation group when compared with the control group.Conclusion.Acupuncture of traditional chinese medicine combined with rehabilitation therapy has outstanding effects in stroke treatment and can effectively improve the neurological function, prognosis, and quality of life of patients, which is worthy of clinical promotion.

Journal: Computational and Mathematical Methods in Medicine (2022)
Publication types: Research Article;
Effect Measurement for Human Motion Rehabilitation Training Using Improved Deep Reinforcement Learning and IoT Networks

Measuring the effect of human motion rehabilitation training is important to help persons develop motion rehabilitation training plans.The current human motion rehabilitation training effect measurement algorithm has the problems of too large gap between the smoothness of the motion speed curve and the reality, high key frame extraction error rate, low measurement accuracy, long measurement time, and low satisfaction.Therefore, this paper proposes a human motion rehabilitation training effect measurement algorithm using improved deep reinforcement learning and internet of things (io t) networks using io t network technology to collect human motion rehabilitation training videos.The key frames of the human motion rehabilitation video data are extracted according to the interframe distance, and the metalearning method is used to improve the deep reinforcement learning network, and the obtained key frames are input into the improved deep reinforcement learning network to obtain the motion speed curve of human motion rehabilitation training.The smoothness of the motion velocity curve is calculated, and high smoothness indicates a good human motion rehabilitation training effect, while low smoothness indicates a poor human motion rehabilitation training effect, so as to complete the measure of human motion rehabilitation training effect.The results show that the smoothness of the motion speed curve of the proposed algorithm is closer to reality, the average error rate of key frame extraction is 1.45%, the measurement accuracy of rehabilitation training is more than 90%, the measurement time is controlled below 2.1 s, and the maximum user satisfaction is 93.1, which shows that the practical application of the algorithm is good.

Journal: Security and Communication Networks (2022)
Publication types: Research Article;