syedzayyan/paper_mill_benchmark huggingface dataset:
Augmented Reality Device for Preoperative Marking of Spine Surgery Can Improve the Accuracy of Level Identification.

Introduction wrong-site spine surgery is an incident that could result in possible severe complications.In this present spinal surgery, the accurate spinal level is confirmed via preoperative or intraoperative radiographic marking.However, the location of radiographic marking has been determined from the manual palpation on the landmarks of the body surface.As a result, severe spine deformity can make it hard to identify the spinal level by manual palpation, thus leading to misidentification of the spinal level.recently, the use of mixed reality in spine surgery is gradually increasing.In this study, we will demonstrate a head-mounted display (hmd) device that can project a hologram (3d image) of the patient's bone onto the actual patient's body to improve the accuracy of level identification for spine surgery.Technical note 3d ct images are created preoperatively, and the bone's stl data (3d data) are generated with the workstation.The created stl data are downloaded to the augmented reality software holoeyes, installed on the hmd.Through this device, surgeons can view the hologram (3d image) of a patient's bone overlaying on an actual patient's body.we temporally estimated the spinous process level only by manual palpation without an hmd.Then, we estimated the spinous process level again after matching this hologram to a real bone with an hmd.The accuracy of the level identification with an hmd and without an hmd was examined by radiographic marking in order to evaluate the misidentification rate of the level.Without an hmd, the misidentification rate of the level was at 26.5%, while with it, the rate was reduced to 14.3%.Conclusions on preoperative marking, an hmd-projecting bone image onto a patient's body could allow us to estimate the spinal level more accurately.Identification of the spinal level using mixed reality is effective in preventing wrong-site spine surgery.

Journal: Spine surgery and related research (2022)
Publication types: Journal Article
End-of-Life Nutrition Considerations: Attitudes, Beliefs, and Outcomes.

To assess the physiological outcomes and interpersonal influences that should be considered when making the decision to provide artificial nutrition and hydration (an&h) for patients in hospice/palliative programs.Methods a systematic review was conducted using items from the preferred reporting items for systematic review and meta-analysis protocols 2015 checklist.Distinct search strategies were employed to find primary research articles that addressed: general health outcomes of artificial nutrition and hydration interventions and nutrition therapy interventions (n = 16), nutrition-related symptoms in end-of-life care (n = 8), and the attitudes of patients and providers toward artificial nutrition and hydration (n = 21).Results the effect of an&h on health outcomes, quality-of-life measures and nutrition-related symptoms is limited and may vary by patient setting and diagnosis.In the absence of consistent evidence for specific health outcomes, decisions regarding an&h should be made in context of the desires and beliefs of a patient, their family, and their medical providers.These beliefs may not be consistent with likely outcomes or may be inconsistent between individuals involved in the decision-making process, and individuals of different cultures or geographic regions may approach an&h decisions from different perspectives.To help navigate the intersection of nutrition-related health outcomes and patient/provider beliefs, palliative care teams may employ a variety of strategies for approaching the decision-making process, and may benefit from specific involvement of a registered dietitian to help contribute to or lead these discussions.

Journal: The American journal of hospice & palliative care (2021)
Publication types: Journal Article;Meta-Analysis;Systematic Review
Factors Contributing to Inappropriate Visits of Frequent Attenders and Their Economic Effects at an Emergency Department in Singapore.

S this study aimed to determine which factors contribute to frequent visits at the emergency department (ed) and what proportion were inappropriate in comparison with nonfrequent visits.Methods this study was a retrospective, case-control study comparing a random sample of frequent attenders and nonfrequent attenders, with details of their ed visits recorded over a 12-month duration.Frequent attenders were defined as patients with four or more visits during the study period.Results in comparison with nonfrequent attenders (median age = 45.0 years, interquartile range [iqr] = 28.0 to 61.0 years), frequent attenders were older (median = 57.5 years, iqr = 34.0 to 74.8 years; p = 0.0003).They were also found to have more comorbidities, where 53.3% of frequent attenders had three or more chronic illnesses compared to 14% of nonfrequent attenders (p < 0.0001), and were often triaged to higher priority (more severe) classes (frequent 52.2% vs.Nonfrequent 37.6%, p = 0.0004).Social issues such as bad debts (12.7%), heavy drinking (3.3%), and substance abuse (2.7%) were very low in frequent attenders compared to western studies.Frequent attenders had a similar rate of appropriate visits to the ed as nonfrequent attenders (55.2% vs.48.1%, p = 0.0892), but were more often triaged to p1 priority triage class (6.7% vs.3.2%, p = 0.0014) and were more often admitted for further management compared to nonfrequent attenders (47.5% vs.29.6%, p < 0.001).The majority of frequent attender visits were appropriate (55.2%), and of these, 81.1% resulted in admission.For the same number of patients, total visits made by frequent attenders ($174,247.60) cost four times as much as for nonfrequent attenders ($40,912.40).This represents a significant economic burden on the health care system.Conclusions ed frequent attenders in singapore were associated with higher age and presence of multiple comorbidities rather than with social causes of ed use.Even in integrated health systems, repeat ed visits are frequent and expensive, despite minimal social causes of acute care.Eds in aging populations must anticipate the influx of vulnerable, elderly patients and have in place interventional programs to care for them.

Journal: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine (2015)
Publication types: Journal Article;Research Support, Non-U.S. Gov't
Early Experience and Results Using Patient-Reported Outcomes Measurement Information System Scores in Primary Total Hip and Knee Arthroplasty.

Our study determined if preoperative patient-reported outcomes measurement information system (promis) scores could predict achieving minimum clinically important differences (mcids) in postoperative promis scores after primary total hip and knee arthroplasty.Methods ninety-three patients were administered the promis depression, pain interference, and physical function domains at their preoperative appointment and 6-week follow-up visit.Mcids were drawn from existing literature for the promis domains.Results the mcid was achieved in 74% of patients for pain interference, 34% for physical function, and 24% for depression.Our model could predict with 90% specificity which patients would meet mcid if their preop promis pain score was above 38, physical function score less than 19, or depression score above 22.Conclusion preoperative promis pain interference, physical function, and depression scores can predict achieving mcid in postoperative promis scores.

Journal: The Journal of arthroplasty (2019)
Publication types: Journal Article
Lived Experiences of Federally Qualified Health Center Board Members During a Period of Rapid Change in New York City (2010-2020).

Federally qualified health centers (fqhcs) provide primary care services in underserved areas and are governed by patient-majority boards.A phenomenological approach was used to explore the lived experiences of board members as they addressed the need for fundamental change to meet the demands of a rapidly changing, highly competitive health care market (2010-2020).Findings were that board members rely upon personal experience and monthly board meetings to be alerted to change that affects health care delivery.They may need additional training to adjust governance and organizational performance to address the new patient consumerism, market conditions, and competition from other providers.

Journal: The Journal of ambulatory care management (2021)
Publication types: Journal Article
Non-Pathological Psychological Distress among Mainland Chinese in Canada and Its Sociodemographic Risk Factors amidst the Pandemic.

The covid-19 pandemic has exacerbated health inequalities, with a potentially heightened mental health risk for mainland chinese in canada, given the rising anti-chinese discrimination, and barriers in assessing health services.In this context, this study aimed to assess non-pathological psychological distress towards covid-19 and identify its sociodemographic risk factors among mainland chinese in canada at the early stages of the pandemic.Methods a sample of 731 mainland chinese aged 16 or older completed an on-line survey to examine their attitudes, behavioural, and psychological responses towards covid-19.Non-pathological psychological distress was assessed with a 7-item self-report scale to capture common emotional reactions towards covid-19.Results a factor analysis revealed a single-factor structure of the 7-item covid-19 psychological distress scale (eigen λ = 3.79).A composite psychological distress index (pdi) score was calculated from these items and used as the outcome variable.Multivariate regression models identified age, financial satisfaction, health status, and perceived/experienced discrimination as significant predictors of psychological distress (ps ≤ 0.05).Conclusions mainland chinese in canada who were over 25, in poor financial/health status, or with perceived/experienced discrimination were at a higher risk for covid-19-related psychological distress.The health inequity across these factors would inform the services to mitigate mental health risk in minority groups.

Journal: Healthcare (Basel, Switzerland) (2022)
Publication types: Journal Article
Usefulness of Body Composition CT Analysis in Patients with Idiopathic Pulmonary Fibrosis: A Pilot Study.

To evaluate the feasibility of a chest ct-based body composition analysis in idiopathic pulmonary fibrosis (ipf), and to investigate the respective contribution of lung and muscle ct quantitative analyses to the prognosis of ipf.Method a total of 71 ipf patients were recruited at diagnosis.All patients underwent a standard chest ct-scan and a bioelectrical impedance analysis considered as reference standard for estimating malnutrition through the use of the fat-free mass index (ffmi).The skeletal muscle index (smi) was measured on chest-ct at the level of the first lumbar vertebra by two radiologists.Lung fibrosis extent was quantified by three radiologists in consensus.The extent of emphysema, the pulmonary artery to aorta (pa/ao) diameter ratio and lymph node enlargement were also reported.Mortality and hospitalization over a 14-month follow-up were recorded.Results a low ffmi defining malnutrition was identified in 26.8% of patients.Smi was significantly lower in these patients (p<0.001) and was correlated with ffmi (r=0.637, p<0.001).Interobserver agreement of smi measurement was very good (icc=0.91).For diagnosing malnutrition, smi showed a 0.79 sensitivity, a 0.69 specificity, a 0.48 ppv and a 0.90 npv.In univariate analysis, fibrosis extent was significantly associated with death, while smi did not reach significance.In multivariate analysis, fibrosis extent and pa/ao ratio were independently associated with hospitalization.Conclusions smi measured on chest ct could be a reliable tool to exclude malnutrition in ipf.A quantitative analysis of both fibrosis and skeletal muscle may allow holistic management of ipf patients.

Journal: Academic radiology (2022)
Publication types: Journal Article
Epigenetic Regulatory Dynamics in Models of Methamphetamine-Use Disorder.

Methamphetamine (meth)-use disorder (mud) is a very serious, potentially lethal, biopsychosocial disease.Exposure to meth causes long-term changes to brain regions involved in reward processing and motivation, leading vulnerable individuals to engage in pathological drug-seeking and drug-taking behavior that can remain a lifelong struggle.It is crucial to elucidate underlying mechanisms by which exposure to meth leads to molecular neuroadaptive changes at transcriptional and translational levels.Changes in gene expression are controlled by post-translational modifications via chromatin remodeling.This review article focuses on the brain-region specific combinatorial or distinct epigenetic modifications that lead to meth-induced changes in gene expression.

Journal: Genes (2021)
Publication types: Journal Article;Research Support, N.I.H., Intramural;Review
How nurses and other health professionals use learning principles in parent education practice: A scoping review of the literature.

Health professionals (hps) play an important role in supporting parents to care for their children, by facilitating parents' knowledge and skills development through parent education.This is achieved through teaching, whereby planned strategies, based on principles of how people learn, enable learning.Despite learning principles being the fundamental tenets of the learning process, how hps perceive and use learning principles in their practice is neglected in the healthcare literature.Objective to identify, describe and map the existing literature on nurses' and hps' perceptions and use of learning principles in parent education practice.Method a scoping review was performed using the joanna briggs institute approach.A comprehensive search of 10 databases and the grey literature was undertaken between march and june 2017 to identify pertinent english-language publications.The search was limited to literature published between 1998 and 2017.Following a screening and inclusion criteria eligibility check, 89 articles were selected for inclusion.Results hps' perceptions of learning principles were diverse, somewhat disorganised, divergent in meaning and implicit.This was until the dimensions of learning construct was applied to guide the analyses and mapping.This revealed that hps, of whom 60.7% were nurses, used learning principles in parent education, but only referred to them in the context of adult learning.Enablers to hps using learning principles included shared partnerships between parents and hps, while barriers included parents' health beliefs, psychological issues and organisational assumptions about learning.Evaluation of parents' learning also represented implicit use of learning principles by hps.Conclusion this scoping review is the first to examine hps' perceptions and use of learning principles within parent education practice.The findings reveal a significant gap in this body of knowledge.The paucity of studies containing any explicit descriptions of learning principles strongly supports the need for further exploration and codification of learning principles, through qualitative methods, whereby a deeper understanding of what is happening in healthcare practice can be established.

Journal: Heliyon (2020)
Publication types: Journal Article;Review
Conservative management of uterine artery pseudoaneurysm occurring during treatment of gestational trophoblastic disease: A case report.

Uterine artery pseudoaneurysm (uap) is a rare disease that causes genital bleeding during the postpartum period after cesarean section.Uterine artery embolization (uae) is an effective procedure for uap.Uap was unexpectedly encountered in a patient with gestational trophoblastic disease; however, this patient was conservatively managed without uae.Uap can occur during treatment for gestational trophoblastic disease.Since asymptomatic uap may spontaneously disappear, in the selection of conservative treatment, it is important to carefully monitor patients using transvaginal ultrasonography focusing on the size of the uap and the speed of internal blood flow.

Journal: The journal of obstetrics and gynaecology research (2020)
Publication types: Case Reports;Journal Article
Healthcare resource utilisation and costs associated with a heart failure diagnosis: a retrospective, population-based cohort study in Sweden.

S to examine healthcare resource use (hru) and costs among heart failure (hf) patients using population data from sweden.Design retrospective, non-interventional cohort study.Setting two cohorts were identified from linked national health registers (cohort 1, 2005-2014) and electronic medical records (cohort 2, 2010-2012; primary/secondary care patients from uppsala and västerbotten).Participants patients (aged ≥18 years) with primary or secondary diagnoses of hf (≥2 international classification of diseases and related health problems, 10th revision classification) during the identification period of january 2005 to march 2015 were included.Outcome measures hru across the hf phenotypes was assessed with logistic regression.Costs were estimated based on diagnosis-related group codes and general price lists.Results total annual costs of secondary care of prevalent hf increased from sek 6.23 (€0.60) to 8.86 (€0.85) billion between 2005 and 2014.Of 4648 incident patients, hf phenotype was known for 1715: reduced ejection fraction (hfr ef): 64.5%, preserved ejection fraction (hfp ef): 35.5%.Within 1 year of hf diagnosis, the proportion of patients hospitalised was only marginally higher for hfr ef versus hfp ef (all-cause (95% ci): 64.7% (60.8 to 68.4) vs 63.7% (60.8 to 66.5), hr 0.91, p=0.14; cardiovascular disease related (95% ci): 61.1% (57.1 to 64.8) vs 60.9% (58.0 to 63.7), hr 0.93, p=0.28).Frequency of hospitalisations and outpatient visits per patient declined after the first year.All-cause secondary care costs in the first year were sek 122 758 (€12 890)/patient/year, with hf-specific care accounting for 69% of the costs.Overall, 10% of the most expensive population (younger; predominantly male; more likely to have comorbidities) incurred ~40% of total secondary care costs.Conclusions hf-associated costs and hru are high, especially during the first year of diagnosis.This is driven by high hospitalisations rates.Understanding the profile of resource-intensive patients being at younger age, male sex and high charlson comorbidity index scores at the time of the hf diagnosis is most likely a sign of more severe disease.

Journal: BMJ open (2021)
Publication types: Journal Article;Research Support, Non-U.S. Gov't
Cystectomy for Benign Indications.

Of review this article evaluates the historical influences, current use, surgical techniques, and recent evidence on outcomes for cystectomy performed for benign indications.Recent findings at the population level, cystectomy for benign indications has similar perioperative morbidity to radical cystectomy for cancer.Postoperative patient satisfaction is high and functional outcomes appear good, including sexual function.Patient regret about diversion choice is low provided decisions are well informed.Cystectomy is important both as a primary procedure for benign disease and as an adjunct to primary urinary diversion.Early morbidity remains high but long-term results are encouraging.Further studies are needed to guide patient decision-making, to help inform diversion choice, and to understand the long-term impact of surgery and diversion choice on quality of life.

Journal: Current urology reports (2022)
Publication types: Journal Article;Review
Factors for Negative Result in Serum Anti-Helicobacter pylori IgG Antibody Test in Adult Subjects With Nodular Gastritis: A Single-center Study.

Nodular gastritis has been demonstrated to be strongly associated with helicobacter pyloriinfection.The present retrospective study was performed to elucidate factors related to a negative serum antibody test result in adults with nodular gastritis.Materials and methods we investigated 116h.Pylori-positive subjects endoscopically diagnosed with nodular gastritis and subjected to a serum anti-h.Pyloriimmunoglobulin g (ig g) antibody test.The degree of gastric mucosal atrophy and the presence of spotty redness in the gastric body and fornix were carefully determined by observations of endoscopic images.Results of the 116 investigated subjects, 108 were positive and 8 negative in serum anti-h.Pylori ig g antibody test results.The degree of gastric mucosal atrophy was mild in seven among eight seronegative cases.The levels of pepsinogen ii in serum in patients with negative antibody test findings were significantly lower as compared to those found positive, while the pepsinogen i/ii ratio tended to be higher in subjects shown negative by the test.Only 1 of 69 with spotty redness was negative in serum anti-h.Pylori ig g antibody testing, while 7 of 47 without spotty redness were negative.Multiple logistic regression analysis of subjects with a negative test result revealed that the absence of spotty redness shown by endoscopy was a significant risk factor.Conclusion the absence of spotty redness, which may reflect the degree of gastric body inflammation, is a significant factor indicating increased risk for a negative serum anti-h.Pylori ig g antibody test result in subjects with nodular gastritis.

Journal: Cureus (2021)
Publication types: Journal Article
Is Myelodysplasia a Consequence of Normal Aging?

Of review to review available data on the relationship of mds and aging and to address the question if biological changes of (premature) aging are a prerequisite for the development of mds.Recent findings whereas the association of mds with advanced age and some common biologic features of aging and mds are well established, additional evidence for both, especially on the role of stem cells, the stem cell niche, and inflammation, has been recently described.Biologically, many but not all drivers of aging also play a role in the development and propagation of mds and vice versa.As a consequence, aging contributes to the development of mds which can be seen as an interplay of clonal disease and normal and premature aging.The impact of aging may be different in specific mds subtypes and risk groups.

Journal: Current oncology reports (2021)
Publication types: Journal Article;Review
Intramural aortic course in anomalous origin of single coronary artery from the right pulmonary artery: A case report and review of the literature.

Preoperatively determining the intramural aortic course in a case of anomalous origin of single coronary artery from the right pulmonary artery is important for planning surgery, such as the unroofing technique.A thin wall separating the ascending aorta from the common coronary artery on transthoracic echocardiography and a crescent-shaped cross-section of the common coronary artery on computed tomography demonstrate an intramural aortic course of the common coronary artery.We present herein a case of anomalous origin of single coronary artery from the right pulmonary artery with an intramural aortic course and review eight other reported cases..

Journal: Journal of cardiology cases (2022)
Publication types: Case Reports;Journal Article