syedzayyan/paper_mill_benchmark huggingface dataset:
Safety of Single-Stage Bilateral Versus Unilateral Anterior Total Hip Arthroplasty: A Propensity-Matched Cohort Study.

Limited data exist on patient safety after single-stage bilateral and unilateral total hip arthroplasty (tha) through the anterior approach (aa).Therefore, the aim of this study was to compare length of stay (los), operative time, 90-day adverse events, 90-day readmission rate, and 1-year revision rate after single-stage bilateral and unilateral tha in matched patients.Methods this was a retrospective matched cohort study of prospectively collected data from 2008 to 2018 of a single-surgeon practice.We used the built-in propensity score matching formula in spss software and matched bilateral and unilateral patient groups on the relevant covariates of age, sex, and body mass index.This resulted in 60 patients undergoing bilateral tha and 60 patients undergoing unilateral tha.Results the average los was 4.7 days (interquartile range [iqr], 3 to 5 days; range, 2 to 21 days) after bilateral tha and 3.0 days (iqr, 2 to 4 days; range, 1 to 13 days) after unilateral tha (p < 0.001).The mean operative time was 140 minutes for bilateral tha and 69 minutes for unilateral tha (p < 0.001).The adverse event rate was 6.7% after bilateral tha and 5.0% after unilateral tha (p = 0.660).The 90-day readmission rate was 3.3% after bilateral tha and 5.0% after unilateral tha (p = 0.321), which also accounted for all of the revisions within the first year.Conclusions when considering single-stage versus staged bilateral aa total hip replacement, patients can expect the same clinical outcome.Because the operative time is longer with bilateral tha, the main advantages are that the patient avoids a second anesthesia session and has an overall shorter recovery time.Level of evidence therapeutic level iii.See instructions for authors for a complete description of levels of evidence.

Journal: The Journal of bone and joint surgery. American volume (2020)
Publication types: Comparative Study;Journal Article
The choice of operation timing of laparoscopic cholecystectomy (LC) after percutaneous transhepatic gallbladder drainage (PTGBD) for acute cholecystitis: a retrospective clinical analysis.

This study aimed to evaluate the timing of laparoscopic cholecystectomy (lc) after percutaneous transhepatic gallbladder drainage (ptgbd).Methods patients with acute moderate to severe cholecystitis treated by lc after ptgbd in the department of hepatobiliary and pancreatic surgery, nankai hospital (n-362) between january 2017 and august 2019were retrospectively enrolled into this study.According to the interval times from ptgbd to lc, the patients were divided into six groups, including group a (105 cases, within 1 week), group b (62 cases, 1-2 weeks), group c (34 cases, 3-4 weeks), group d (54 cases, 5-8 weeks), group e (24 cases, 9-12 weeks), and group f (83 cases, over 12 weeks).The gender, age, hospital stay, duration of operation, rate of conversion to laparotomy, incidence of complications, and hospitalization expenses of the six groups were evaluated and compared.Results of the 362 cases of lc, 346 patients were operated successfully (95.6%), 10 were converted to laparotomy (2.8%), 16 had various complications (4.4%), and 2 died (0.6%).There were no significant differences between groups in the gender ratio, complication rate, and rate of conversion to laparotomy.The hospital stay and hospitalization expenses in group a were the least and significantly lower than those in other groups (p<0.01), and the duration of operation in group d was the longest and significantly higher than that in groups a, b, e, and f (p<0.05).Conclusions for non-elderly patients diagnosed with acute moderate to severe cholecystitis with an anesthesia risk score [american society of anesthesiologists (asa)] ≤2, lc is recommended to be performed within 1 week after ptgbd surgery.If delayed lc is performed within 2 to 8 weeks after ptgbd, the operation time will be longer due to inflammatory edema and fibrous adhesion of the gallbladder triangle.If ptgbd is performed for more than 2 months and the clinical circumstances are good, delayed lc can be considered to reduce the inconvenience of patients with a long-term catheter as much as possible.

Journal: Annals of palliative medicine (2021)
Publication types: Journal Article
A systematic review and meta-analysis on dropout of infertility treatments and related reasons/factors.

Dropout of infertility treatments is a common phenomenon and many patients avoid continuing infertility treatments.Determining the total rate of treatment dropout, and related factors was the objective of the present systematic review and meta-analysis study.We performed an electronic literature search in web of science, scopus, embase, cinhal, pro quest and medline databases and a manual search in google scholar by using a set of standard keywords.We included descriptive studies in english or persian, from august 2000 to 2019.Finally, we extracted data of 25 papers for systematic review and 11 papers for meta-analysis.Data analysed by rev man software.The results of the meta-analysis analysed by the random-effects model and studies heterogeneity analysed using the i2 calculation index.We tried to control high heterogeneity (because of the small amounts ofpvalue and chi-square and large amount of i2) with statistical methods such as subgroup analysis and using random-effects model.The results showed that factors related to treatment, psychological and demographic/personal factors are the most common factors for dropout.It seems that educational and supportive programs on psychological, financial, therapeutic, demographic and personal factors can play an important role in reducing the incidence of infertility treatment's drop out before completing the course of treatment.

Journal: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology (2022)
Publication types: Journal Article;Meta-Analysis;Systematic Review
Review of Ultrasonic Ranging Methods and Their Current Challenges.

Ultrasonic ranging has been widely used in automobiles, unmanned aerial vehicles (uavs), robots and other fields.With the appearance of micromachined ultrasonic transducers (muts), the application of ultrasonic ranging technology presents a more extensive trend.This review focuses on ultrasonic ranging technology and its development history and future trend.Going through the state-of-the-art ultrasonic ranging methods, this paper covers the principles of each method, the signal processing methodologies, the overall system performance as well as key ultrasonic transducer parameters.Moreover, the error sources and compensation methods of ultrasonic ranging systems are discussed.This review aims to give an overview of the ultrasonic ranging technology including its current development and challenges.

Journal: Micromachines (2022)
Publication types: Journal Article;Review
Short-Term Ingestion of Medium-Chain Triglycerides Could Enhance Postprandial Consumption of Ingested Fat in Individuals with a Body Mass Index from 25 to Less than 30: A Randomized, Placebo-Controlled, Double-Blind Crossover Study.

The elimination of obesity is essential to maintaining good health.Medium-chain triglycerides (mcts) inhibit fat accumulation.However, studies examining energy expenditure and fat oxidation with continuous ingestion of mcts show little association with the elimination of obesity.In this study, we conducted a randomized, double-blind crossover clinical trial to investigate the effects of continuous ingestion of mcts on postprandial energy expenditure and ingested long-chain triglycerides (lcts) oxidation.A daily 2 g of mcts were ingested for two weeks by sedentary participants with a body mass index (bmi) from 25 (kg/m2) to less than 30.Ingestion of a meal containing mcts and isotopic carbon-13-labeled (13c) lcts increased energy expenditure and consumption of diet-derived lcts, as determined by postprandial 13c carbon dioxide excretion, compared to canola oil as the placebo control.These results indicate that continuous ingestion of mcts could enhance postprandial degradation of diet-derived fat and energy expenditure in sedentary, overweight individuals.

Journal: Nutrients (2022)
Publication types: Journal Article;Randomized Controlled Trial
Differences in Postacute Rehabilitation Recommendations by Ethnicity at an Urban Comprehensive Stroke Center.

The aim of this study was to investigate differences in postacute rehabilitation discharge recommendations, actual disposition, and rehabilitation duration by ethnicity at an urban joint commission comprehensive stroke center.Design this was a retrospective cohort study of adult acute stroke hospital admissions between january 1, 2016, and december 31, 2019 (n = 1717) who were discharged to home with or without outpatient therapy, inpatient rehabilitation facility, or skilled nursing facility (snf).Lognormal and multinomial regressions were used to create statistical models evaluating ethnicity-related differences in discharge recommendation and disposition as well as rehabilitation duration while controlling for age, stroke type and severity, insurance type, and medical comorbidities; non-hispanic white (nhw) patients served as the comparison group.Results hispanic patients were less likely to have therapy recommendations of snf, with a trend toward significance (p = 0.06), yet statistically more likely to have the actual disposition of snf (p = 0.01) than nhw patients.There were no statistically significant differences comparing disposition rates for black and asian patients to nhw patients for both inpatient rehabilitation facility and snf.There was no statistically significant difference in rehabilitation duration for black or hispanic patients compared with nhw patients.Conclusions hispanic patients were less likely to have therapy recommended snf disposition, with a trend toward significance, but significantly more likely to have actual snf disposition compared with nhw patients after acute stroke.

Journal: American journal of physical medicine & rehabilitation (2022)
Publication types: Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
The Role of Protein Arginine Methyltransferases in DNA Damage Response.

In response to dna damage, cells have developed a sophisticated signaling pathway, consisting of dna damage sensors, transducers, and effectors, to ensure efficient and proper repair of damaged dna.During this process, posttranslational modifications (ptms) are central events that modulate the recruitment, dissociation, and activation of dna repair proteins at damage sites.Emerging evidence reveals that protein arginine methylation is one of the common ptms and plays critical roles in dna damage response.Protein arginine methyltransferases (prmts) either directly methylate dna repair proteins or deposit methylation marks on histones to regulate their transcription, rna splicing, protein stability, interaction with partners, enzymatic activities, and localization.In this review, we summarize the substrates and roles of each prmts in dna damage response and discuss the synergistic anticancer effects of prmts and dna damage pathway inhibitors, providing insight into the significance of arginine methylation in the maintenance of genome integrity and cancer therapies.

Journal: International journal of molecular sciences (2022)
Publication types: Journal Article;Review
An investigation of associations between experience of childhood trauma and political violence and theory of mind impairments in schizophrenia.

There has been little examination of the association between trauma and cognitive deficits seen in individuals diagnosed with schizophrenia.Theory of mind (to m) impairments are a significant feature of schizophrenia but it remains unclear as to why these deficits are so prevalent in this population.This study aimed to explore associations between to m deficits and specific forms of childhood adversities in a schizophrenia population.The study sample comprised of 66 adults with a confirmed diagnosis of schizophrenia, attending mental health services in northern ireland.Assessments were completed to ascertain if individuals had prior experience of sexual or physical abuse, emotional neglect or experience of the political violence of northern ireland's "troubles", and the gardner hinting test was applied to assess to m ability.Backwards stepwise regression analyses demonstrated that emotional neglect, specifically during early childhood (0-6 years) predicted to m impairments in this group.Conflict-related trauma was also associated with to m but was not an independent significant predictor of to m deficits.This is the first study to examine links between specific forms of childhood adversity and to m impairments in individuals diagnosed with schizophrenia.Potential underpinning psychological mechanisms are considered and implications for clinical practice are discussed.

Journal: Psychiatry research (2018)
Publication types: Journal Article
Nitrofurantoin and Minocycline-Associated Vasculitic Neuropathy: Case Reports and Literature Review.

Vasculitic neuropathies usually present acutely to subacutely, with an asymmetric pattern, involving multiple peripheral nerve territories.Drug-induced vasculitis is an often overlooked etiology of vasculitic neuropathy.Methods we present the first reported case of nitrofurantoin-associated and an illustrative case of minocycline-associated vasculitic neuropathy, with a review of the literature.Results the first patient is a 60-year-old woman who developed axonal sensorimotor peripheral neuropathy after nitrofurantoin use, with a superficial radial nerve biopsy confirming vasculitis.The second patient is a 23-year-old woman, with a history of acne vulgaris treated with minocycline, who presented with a subacute right common peroneal mononeuropathy followed by a left deep peroneal mononeuropathy, with elevated antinuclear, perinuclear-antineutrophil cytoplasmic, and myleoperoxidase antibodies, and mpo titers, and a sural nerve biopsy showing large arteriole vasculitis.Finally, we provide a comprehensive review of previously published cases.Conclusions medications should be considered as a trigger for medication-induced vasculitic neuropathy.Accurate diagnosis would ensure timely treatment.

Journal: Journal of clinical neuromuscular disease (2022)
Publication types: Review;Case Reports;Journal Article
Anorectal dysfunction in adults with spina bifida and associated socio-emotional factors-a retrospective, cross-sectional cohort study.

Study design retrospective, cross-sectional study.Objectives to investigate prevalence, types, and severity of fecal incontinence (fi) and constipation in adults with spina bifida (sb), in relation to self-perception and help-seeking, and to compare findings to data from a general population reference group.Setting university medical center groningen (umcg), the netherlands.Methods the 294 adults with sb registered at umcg in 2017 were invited to participate.The groningen defecation and fecal continence questionnaire was used to assess functional outcomes for fi and constipation using rome iv criteria.Vaizey (for fi) and agachan (for constipation) scores were determined.Socio-demographic factors and self-perception of bowel-related problems were recorded through the questionnaire.Data were compared with an age and sex matched reference group.Results the completed questionnaires of 112 (38%) responding participants were analyzed.Fi and constipation were more prevalent in the study group (35% and 45%, respectively) than in the reference group (8.9% and 22%, respectively).In general, in participants with sb aperta (sba; n = 75), fi was more severe than in participants with sb occulta (sbo; n = 37).However, severity of fi was higher in sbo participants than in the sba group after the age of 61.Bowel problems in adults with sb were associated with worse self-perception regarding health.Conclusions in adults with sb, anorectal dysfunction is often present and severe.Older persons with sbo experience more severe fi than in early age.Bowel problems should systematically and more adequately be addressed and controlled throughout adulthood in both the spina bifida groups.

Journal: Spinal cord (2022)
Publication types: Journal Article
Development of a score for early identification of children with Kawasaki disease requiring second-line treatment in multi-ethnic populations in Europe: A multicentre retrospective cohort study.

Early identification of high-risk patients is essential to stratify treatment algorithms of kawasaki disease (kd) and to appropriately select patients at risk for complicated disease who would benefit from intensified first-line treatment.Several scores have been developed and validated in asian populations but have shown low sensitivity in predicting intravenous immunoglobulin (ivig) resistance in non-asian populations.We sought methods to predict the need for secondary treatment after initial ivig in non-asian populations.Methods we conducted a retrospective, multicenter study including consecutive patients with kd admitted to two tertiary pediatric hospitals in france and italy from 2005 to 2019.We evaluated the performance of the kawanet-score and compared it with the performances of initial echocardiography findings, and of a newly proposed score combining the kawanet-score and initial echocardiography findings.For each score, we assessed the auc, sensitivity and specificity for predicting the need for second-line treatment.Findings we included 363 children with kd, 186 from france and 177 from italy, of whom 57 (16%) required second-line therapy after the first ivig dose.The kawanet score, coronary artery dilation or aneurysm with maximal z-score ≥2.0 at baseline, and abnormal initial echocardiography had a sensitivity of 43%, 55% and 65% and a specificity of 73%, 78%, 73%, respectively, for predicting the need for second-line treatment.The kawanet-score was significantly improved by combining it with initial echocardiography findings.The best predictive performance (sensitivity 76%, specificity 54%) was obtained by combining the kawanet-score with abnormal initial echocardiography, defined by the presence of either coronary artery maximal z-score ≥2.0, pericarditis, myocarditis and/or ventricular dysfunction.This score predicted the need for second-line treatment in european, african/afro-caribbean and asian ethnicity with a sensitivity of 80%, 65% and 100%, respectively, and a specificity of 56%, 51% and 61%, respectively.Interpretation our study proposes a score that we named the kawanet-echo score, which allows early identification of children with kd who require a second-line treatment in multi-ethnic populations in europe.Funding none.

Journal: The Lancet regional health. Europe (2022)
Publication types: Journal Article
HCV communication within ego-centric networks of men and women who inject drugs.

Introduction leveraging interpersonal communication among social networks of people who inject drugs (pwid) may be an innovative strategy to increase awareness and access to hepatitis c (hcv) care.However, little is known about hcv communication patterns among pwid and if these patterns vary by gender.Methods egocentric network data collected at baseline from hcv-infected pwid enrolled in a randomized hcv treatment intervention trial in baltimore, maryland were analyzed.Logistic generalized estimating models were conducted to identify predictors of hcv communication.Results among 227 pwid, the mean age was 43.8 (sd=10.3), 28.2% (n = 64) were women and 71.8% (n = 163) were men.Female participants reported 516 dyadic relationships and male participants 1139 dyadic relationships.While there were significant gender differences based on socio-demographics, risk behavior and network composition, there were few differences in hcv communication patterns.Both men and women had increased odds of hcv communication with alters who are currently enrolled in drug treatment (aor 1.7, 95% ci: 1.3-2.4), alters with whom participants share drug preparation equipment (aor 3.0, 95% ci: 1.9-4.6), alters who are sex partners compared to kin (aor 3.0; 95% ci: 1.9-4.9) and alters with whom respondents have increased trust (aor 1.1; 95% ci: 1.11.2) and daily/weekly interactions (aor 1.7; 95% ci 1.3-2.1).Conclusion pwid engaged with trusted alters about hcv disclosure and information, highlighting the important role network interventions could play in this vulnerable population.

Journal: Drug and alcohol dependence (2021)
Publication types: Journal Article;Randomized Controlled Trial;Research Support, N.I.H., Extramural
Mechanical Integrity Degradation and Control of All-Solid-State Lithium Battery with Physical Aging Poly (Vinyl Alcohol)-Based Electrolyte.

Ensuring the material durability of an electrolyte is a prerequisite for the long-term service of all-solid-state batteries (assbs).Herein, to investigate the mechanical integrity of a solid polymer electrolyte (spe) in an assb upon electrochemical operation, we have implemented a sequence of quasi-static uniaxial tension and stress relaxation tests on a lithium perchlorate-doped poly (vinyl alcohol) electrolyte, and then discussed the viscoelastic behavior as well as the strength of spe film during the physical aging process.On this basis, a continuum electrochemical-mechanical model is established to evaluate the stress evolution and mechanical detriment of aging electrolytes in an assb at a discharge state.It is found that the measured elastic modulus, yield stress, and characteristic relaxation time boost with the prolonged aging time.Meanwhile, the shape factor for the classical time-decay equation and the tensile rupture strength are independent of the aging history.Accordingly, the momentary relaxation modulus can be predicted in terms of the time-aging time superposition principle.Furthermore, the peak tensile stress in spe film for the full discharged assb will significantly increase as the aging proceeds due to the stiffening of the electrolyte composite.It may result in the structure failure of the cell system.However, this negative effect can be suppressed by the suggested method, which is given by a 2d map under different lithiation rates and relative thicknesses of the electrolyte.These findings can advance the knowledge of spe degradation and provide insights into reliable all-solid-state electrochemical device applications.

Journal: Polymers (2020)
Publication types: Journal Article
Communication in interprofessional rehabilitation teams: a scoping review.

Effective communication in interprofessional rehabilitation teams is essential for optimal patient care.Despite the established importance, it remains unclear how interprofessional communication (ipc) within teams contributes to rehabilitation service delivery.The aim of this scoping review was to investigate how ipc has been described in rehabilitation literature.Methods databases (medline, cinahl, eric, embase, psych info, and academic search complete) were searched for studies including rehabilitation interprofessional communication.Inclusion and exclusion criteria were identified and applied, data were charted, and thematic analysis conducted.Results twenty-nine papers were identified, and analysis revealed interrelated themes: communication processes, and inputs and effects.Formal communication processes were most prevalent, portraying variability in professional participation and a lack of patient involvement in dialogue and decision making.Inputs and effects were described at an organisational, team and individual level, highlighting the importance of communication throughout the healthcare hierarchy.Conclusions ipc in rehabilitation is central to effective team function and patient care.To further our understanding, empirical studies examining everyday informal ipc, as well as formal ritualised encounters are needed.Additionally, conceptualisations of ipc would benefit from including the patients' perspective and by using theoretical framing to attend to places, spaces, and artefacts identified in this review.

Journal: Disability and rehabilitation (2022)
Publication types: Journal Article;Review