syedzayyan/paper_mill_benchmark huggingface dataset:
A BEHAVIORALLY-INTEGRATED INDIVIDUAL-LEVEL STATE-TRANSITION MODEL THAT CAN PREDICT RAPID CHANGES IN EVACUATION DEMAND DAYS EARLIER.

Timely and accurate forecast of evacuation demand is key for emergency responders to plan and organize effective evacuation efforts during a disaster.The state-of-the-art in evacuation demand forecasting includes behavior-based models and dynamic flow-based models.Both lines of work have critical limitations: behavioral models are static, meaning that they cannot adjust model predictions by utilizing field observation in real time as the disaster is unfolding; and the flow-based models often have relatively short prediction windows ranging from minutes to hours.Consequently, both types of models fall short of being able to predict sudden changes (e.g., a surge or abrupt drop) of evacuation demand in advance.This paper develops a behaviorally-integrated individual-level state-transition model for online predictions of evacuation demand.On a daily basis, the model takes in observed evacuation data and updates its forecasted evacuation demand for the future.An individual-level survival model formulation is innovatively devised for the state-transition model to account for history-dependent transition probabilities and allow individual heterogeneity.A bayesian updating approach is employed to assimilate observed evacuation data in real time.To enable a longer-term perspective on how evacuation demand may evolve over time so that rapid surges or drops in demand can be predicted days in advance, the model integrates insights from existing behavioral curves (either from past disasters or simply expert opinions).Using a likelihood-based approach, the state-transition model integrates the future trends of evacuation demand informed by the behavioral curve when updating its forecasts.Theoretical proof is also provided showing that the likelihood function guarantees a unique global solution to the state-transition model.The proposed model is tested in six scenarios using mobile app-based data for hurricane harvey that hit the us in 2017.The results demonstrate overall robustness of the proposed model: in all six scenarios, the model is able to predict accurately the occurrence of the rapid surges or drops in evacuation demand at least two days ahead.The current study contributes to the field of evacuation modeling by integrating the two lines of work (behavior-based and flow-based models) using mobile app-based data.

Journal: Transportation research. Part E, Logistics and transportation review (2021)
Publication types: Journal Article
Long-term joint outcomes in adolescents with moderate or severe haemophilia A.

Introduction favourable joint outcomes are expected with modern haemophilia a (ha) management.Evaluation of long-term treatment outcomes is hampered by the delay between bleeding episodes during childhood and resulting joint outcomes in adulthood.Aim to measure the long-term joint health of adolescents with moderate and severe ha, according to severity and inhibitor status.Methods pilot cross-sectional study of five european ped net centres in moderate and severe ha patients aged 10-19 years.Structured assessment of joint status by physical examination (hjhs) and ultrasound (head-us).Results in total, 141 ha patients were evaluable, 100 without inhibitors (81 severe, 19 moderate ha), and 41 severe ha with current/past inhibitors.On physical examination, 12/81 (15%) of severe ha without inhibitors, 3/19 (16%) of moderate ha, and 13/41 (32%) of severe ha patients with inhibitors exhibited joint abnormalities.Inhibitor persistence, longer inhibitor duration, and a high peak inhibitor level were associated with impaired joint health.Ultrasound showed joint damage (bone or cartilage) in 13/49 (27%) of severe ha without inhibitors, 1/12 (8%) of moderate ha, and 10/28 (36%) of severe ha patients with inhibitors.A discordant ankle evaluation by ultrasound versus physical examination was present in 53/169 joints (31%).Conclusions most adolescents with severe or moderate ha show favourable joint health.Future research with combined ultrasound and/or mri is needed to better understand joint outcomes in the remaining patients.Patents with inhibitors showed a two-fold increased proportion with joint deterioration.Ultrasound paired with physical examination increases sensitivity for detection of joint damage.

Journal: Haemophilia : the official journal of the World Federation of Hemophilia (2022)
Publication types: Journal Article
Postmenopausal osteoporosis and breast cancer: The biochemical links and beneficial effects of functional foods.

Breast cancer as a multifactorial disease has been classified among the major causes of morbidity and mortality in women across the world, with a higher prevalence among post-menopausal women.Osteoporosis, a condition characterized by altered bone mineralization is also commonly found among post-menopausal women.Consequently, post-menopausal women are at risk of morbidity and mortality associated with breast cancer and postmenopausal osteoporosis.This may not be unconnected to the fact that, there may be existent biochemical links between the two mayhems, which might rally round between the cellular and molecular connectivity based on the actions and inactions of rankl, estrogen, free radicals-induced oxidative stress and metabolic implications of age related obesity among others.Cells and tissues including breast and bone are more prone to oxidative stress with age, and oxidative stress could alter the activity of key proteins and pathways required for protection against breast cancer and osteoporosis.As a result, the potentials of antioxidant rich functional foods in preventing, managing and possibly treating breast cancer and postmenopausal osteoporosis cannot be overemphasised.This review mainly uses isi, scopus and pub med indexed journals and books containing various experimental reports vacillating from humans, animals and in vitro studies in relation to breast cancer and postmenopausal osteoporosis, biochemical links and possible beneficial effects of functional foods.One distinct feature of the review is that it categorically intends to provide a critical appraisal on the said available experimental data within the variables of breast cancer and osteoporosis among females vis-à-vis the potentials of functional foods.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie (2018)
Publication types: Journal Article;Review
Accuracy of a markerless motion capture system in estimating upper extremity kinematics during boxing.

Kinematic analysis of the upper extremity can be useful to assess the performance and skill levels of athletes during combat sports such as boxing.Although marker-based approach is widely used to obtain kinematic data, it is not suitable for "in the field" activities, i.e., when performed outside the laboratory environment.Markerless video-based systems along with deep learning-based pose estimation algorithms show great potential for estimating skeletal kinematics.However, applicability of these systems in assessing upper-limb kinematics remains unexplored in highly dynamic activities.This study aimed to assess kinematics of the upper limb estimated with a markerless motion capture system (2d video cameras along with commercially available pose estimation software theia3d) compared to those measured with marker-based system during "in the field" boxing.A total of three elite boxers equipped with retroreflective markers were instructed to perform specific sequences of shadow boxing trials.Their movements were simultaneously recorded with 12 optoelectronic and 10 video cameras, providing synchronized data to be processed further for comparison.Comparative assessment showed higher differences in 3d joint center positions at the elbow (more than 3 cm) compared to the shoulder and wrist (<2.5 cm).In the case of joint angles, relatively weaker agreement was observed along internal/external rotation.The shoulder joint revealed better performance across all the joints.Segment velocities displayed good-to-excellent agreement across all the segments.Overall, segment velocities exhibited better performance compared to joint angles.The findings indicate that, given the practicality of markerless motion capture system, it can be a promising alternative to analyze sports-performance.

Journal: Frontiers in sports and active living (2022)
Publication types: Journal Article
Fitness to practise sanctions in UK doctors are predicted by poor performance at MRCGP and MRCP(UK) assessments: data linkage study.

The predictive validity of postgraduate examinations, such as mrcgp and mrcp(uk) in the uk, is hard to assess, particularly for clinically relevant outcomes.The sanctions imposed on doctors by the uk's general medical council (gmc), including erasure from the medical register, are indicators of serious problems with fitness to practise (ft p) that threaten patient safety or wellbeing.This data linkage study combined data on gmc sanctions with data on postgraduate examination performance.Methods examination results were obtained for uk registered doctors taking the mrcgp applied knowledge test (akt; n = 27,561) or clinical skills assessment (csa; n = 17,365) at first attempt between 2010 and 2016 or taking mrcp(uk) part 1 (mcq; n = 37,358), part 2 (mcq; n = 28,285) or practical assessment of clinical examination skills (paces; n = 27,040) at first attempt between 2001 and 2016.Exam data were linked with gmc actions on a doctor's registration from september 2008 to january 2017, sanctions including erasure, suspension, conditions on practice, undertakings or warnings (escuw).Examination results were only considered at first attempts.Multiple logistic regression assessed the odds ratio for escuw in relation to examination results.Multiple imputation was used for structurally missing values.Results doctors sanctioned by the gmc performed substantially less well on mrcgp and mrcp(uk), with a mean cohen's d across the five exams of - 0.68.Doctors on the 2.5th percentile of exam performance were about 12 times more likely to have ft p problems than those on the 97.5th percentile.Knowledge assessments and clinical assessments were independent predictors of future sanctions, with clinical assessments predicting escuw significantly better.The log odds of an ft p sanction were linearly related to examination marks over the entire range of performance, additional performance increments lowering the risk of ft p sanctions at all performance levels.Conclusions mrcgp and mrcp(uk) performance are valid predictors of professionally important outcomes that transcend simple knowledge or skills and the gmc puts under the headings of conduct and trust.Postgraduate examinations may predict ft p sanctions because the psychological processes involved in successfully studying, understanding and practising medicine at a high level share similar mechanisms to those underlying conduct and trust.

Journal: BMC medicine (2018)
Publication types: Journal Article;Research Support, Non-U.S. Gov't
Effects of replacing soy protein and bread crumb with quinoa and buckwheat flour in functional beef burger formulation.

This study investigated the physicochemical, nutritional and sensorial characteristics of beef burgers formulated with quinoa flour (qf) and buckwheat flour (bwf) as replacers of the mixture of soy protein powder (sp) and bread crumb (bc).Six treatments were formulated in two groups (15% and 30% of added flour as groups a and b, respectively).The oil absorption and water holding capacity were higher (p < 0.05) in soy protein burgers (spb) than in other burgers.The mineral content of magnesium, phosphorus, iron and zinc was higher in the quinoa burgers (qb) than in the other formulations for both a and b groups.Also, the result of sensory evaluation revealed increases (p < 0.05) in overall acceptability and taste attributes of qb and bwb (buckwheat burger) in both groups.The shelf life results showed significant differences between spb and treated samples (qb and bwb).Therefore, these new beef burger formulations might be a viable option in improvement of nutritional, durability and sensory properties.

Journal: Meat science (2021)
Publication types: Journal Article
Manipulating the Optoelectronic Properties of Quasi-type II CuInS2/CdS Core/Shell Quantum Dots for Photoelectrochemical Cell Applications.

Colloidal core/shell heterostructured quantum dots (qds) possessing quasi-type ii band structure have demonstrated effective surface passivation and prolonged exciton lifetime, leading to enhanced charge separation/transfer efficiencies that are promising for photovoltaic device applications.Herein, we synthesized cu in s2(cis)/cd s core/shell heterostructured qds and manipulated the optoelectronic properties via controlling the cd s shell thickness.The shell-thickness-dependent optical properties indicate the existence of a quasi-type ii band structure in such core/shell qds, which was verified by ultrafast spectroscopy and theoretical simulations.These quasi-type ii core/shell qds having various shell thicknesses are used as light absorbers for the fabrication of solar-driven qds-based photoelectrochemical (pec) devices, exhibiting an optimized photocurrent density of ∼6.0 m a/cm2and excellent stability under simulated am 1.5g solar illumination.The results demonstrate that quasi-type ii cis/cd s core/shell heterostructured qds with tailored optoelectronic properties are promising to realize high-performance qds-based solar energy conversion devices for the production of solar fuels.

Journal: ACS applied materials & interfaces (2020)
Publication types: Journal Article
Emergence of KPC-31, a KPC-3 Variant Associated with Ceftazidime-Avibactam Resistance, in an Extensively Drug-Resistant ST235 Pseudomonas aeruginosa Clinical Isolate.

A ceftazidime-avibactam-resistant kpc-producing pseudomonas aeruginosa strain was isolated in argentina from a tracheal aspirate.The patient was treated with ceftazidime-avibactam in combination with other agents for 130 days.Whole-genome sequencing of p.Aeruginosa identified a d179y substitution in the ω loop of kpc-3, corresponding to kpc-31, integrated at the chromosome.The strain belonged to the sequence type 235/o11 (st235/o11) high-risk clone.Evaluation of carbapenemase detection assays most used by clinical laboratories failed to identify the isolate as a kpc producer.

Journal: Antimicrobial agents and chemotherapy (2022)
Publication types: Journal Article
Kronecker delta method for testing independence between two vectors in high-dimension.

Conventional methods for testing independence between two gaussian vectors require sample sizes greater than the number of variables in each vector.Therefore, adjustments are needed for the high-dimensional situation, where the sample size is smaller than the number of variables in at least one of the compared vectors.It is critical to emphasize that the methods available in the literature are unable to control the type i error probability under the nominal level.This fact is evidenced through an intensive simulation study presented in this paper.To cover this lack, we introduce a valid randomized test based on the kronecker delta covariance matrices estimator.As an empirical application, based on a sample of companies listed on the stock exchange of brazil, we test the independence between returns of stocks of different sectors in the covid-19 pandemic context.

Journal: Statistical papers (Berlin, Germany) (2022)
Publication types: Journal Article
The future is present in the past: A meta-analysis on the longitudinal associations of parent-adolescent relationships with peer and romantic relationships.

Positive peer and romantic relationships are crucial for adolescents' positive adjustment and relationships with parents lay the foundation for these relationships.This longitudinal meta-analysis examined how parent-adolescent relationships continue into later peer and romantic relationships.Included longitudinal studies (k = 54 involving peer relationships, k = 38 involving romantic relationships) contained demographically diverse samples from predominantly western cultural contexts.Multilevel meta-regressions indicated that supportive and negative parent-adolescent relationships were associated with supportive and negative future peer and romantic relationships.Meta-analytic structural equation modeling (k = 54) indicated that supportive parent-adolescent relationships unidirectionally predicted supportive and negative peer relationships, while negative parent-adolescent relationships were bidirectionally associated with supportive and negative peer relationships.Maintaining mutually supportive relationships with parents may help adolescents to develop positive social relationships.

Journal: Child development (2023)
Publication types: Meta-Analysis;Journal Article;Review;Research Support, Non-U.S. Gov't
Quality of life after thoracic sympathectomy for palmar hyperhidrosis: a meta-analysis.

Palmar hyperhidrosis affects 0.6-10% of the general population, having an important impact in patients' quality of life.The definitive treatment for palmar hyperhidrosis is thoracic sympathectomy.The purpose of this study is to evaluate the quality of life after thoracic sympathectomy for palmar hyperhidrosis.Methods the interest studies were searched in six comprehensive databases.The quality of the studies was assessed using the risk of bias tool recommended by the cochrane system evaluation manual.Meta-analysis was performed with rev man version 5.3.The outcome of interest was quality of life.The subgroup analysis and sensitive analysis were performed.Results nine trials, including 895 patients, with accessible data comparing preoperative quality of life score with postoperative quality-of-life score were used for data analysis.Compared with preoperative quality-of-life score, application of thoracic sympathectomy improved the postoperative quality of life of palmar hyperhidrosis patients (md = 57.81, 95% ci 53.33-62.30).Subgroup analysis of the different thoracic sympathectomy segment showed that there was no significant difference in the results obtained when operated with single segment or multiple segments (single segment: md = 61.16, 95% ci [56.10, 66.22], multiple segments: md = 52.14, 95% ci [48.39, 55.88]).Conclusion the meta-analysis provided evidence of the improved quality of life after thoracic sympathectomy for palmar hyperhidrosis.

Journal: General thoracic and cardiovascular surgery (2020)
Publication types: Journal Article;Meta-Analysis;Systematic Review
Distinct Mechanisms in Number Comparison of Random and Regular Dots: An ERP Study.

Numerosity comparison for regular patterns shows different features compared with that for random ones in previous studies, suggesting an underlying mechanism distinct from numerosity.In this study, we went further to compare the event-related potentials (erp) components in numerosity processing of random and regular patterns, which are identical in all aspects of texture features except for the distribution.Erp components were recorded and analyzed while participants compared which of the two successively presented sets was more numerous.P2p amplitude was revealed to be significantly weaker for regular patterns compared with that for random patterns over right occipital-parietal cites, whereas no difference was found for p1 or n1 components.The difference in p2p amplitude, which is consistent with the behavior dissociation revealed in our previous studies, suggests that regular distribution can trigger distinct processing in numeral comparison tasks.Processing of continuous magnitudes or configuration cannot explain the decrease in p2p amplitude for regular distributed patterns.Therefore, this study further supports that p2p is mediated by numerosity processing.

Journal: Frontiers in behavioral neuroscience (2021)
Publication types: Journal Article
Pathways from exposure to racial/ethnic discrimination to depression: Testing a social-cognitive model.

Rationale and objective interpersonal racial/ethnic discrimination is a risk factor for depression across the lifespan in minoritized racial/ethnic groups.This study tests a model proposing that social cognitive processes, including relational schemas, mediate the link between discrimination and depression.Relational schemas enable individuals to form mental representations of others, reflecting prior social learning and generating expectations about future social relations.Racism-related relational schemas include, among others, concerns about being rejected or invalidated, concerns about confirming negative stereotypes held by others, and cynical mistrust of others.Prior studies have typically examined the mediating role of one or two relational schemas in the association between discrimination and depression; less is known about the unique and combined effects of multiple dimensions of racism-related social cognition.Methods the model was tested in a convenience sample of ethnically diverse, non-white participants recruited from two sites, a community medical center (n = 136; mage= 38, sd = 13.0) and a private university (n = 120; mage= 19.4, sd = 1.3), yielding a consolidated sample of 256 participants (64% women).Data were collected between september 2016 and april 2018.Participants completed paper-and-pencil self-report measures of exposure to interpersonal discrimination, depressive symptoms, and eight measures of relational schemas.Results confirmatory factor analysis indicated that the eight relational schemas defined three primary dimensions: concerns about rejection and invalidation, social vigilance, and mistrust.A structural equation model in which the association between exposure to discrimination and depressive symptoms operates through latent factors representing three social-cognitive dimensions demonstrated adequate fit (cfi = 0.96, rmsea = 0.06, srmr = 0.04).A significant mediational effect was found only for concerns about rejection and invalidation.Conclusion the conceptual model supported by this study may help inform psychological interventions aimed at mitigating the detrimental effects of racial/ethnic discrimination on mental health.

Journal: Social science & medicine (1982) (2022)
Publication types: Journal Article;Research Support, Non-U.S. Gov't