syedzayyan/paper_mill_benchmark huggingface dataset:
Clinical Features and Laboratory Examination Results of Sjogren’s Syndrome Complicated with Thyroid Disorders: A Retrospective Analysis

To analyze the clinical incidence, clinical manifestations, laboratory examination, and complications of sjogren’s syndrome complicated with thyroid disorders in patients and to explore the clinical significance of its occurrence and concurrence relationship.Methods.The clinical manifestations, thyroid function, antithyroid antibodies, immunology indicators, autoantibodies, and routine laboratory examination items of 201 patients with sjogren’s syndrome in chongqing hospital of traditional chinese medicine were reviewed and analyzed.According to whether the thyroid function was abnormal or not, the patients were divided into the group of sjogren’s syndrome complicated with abnormal thyroid function (n = 36) and the group of sjogren’s syndrome without abnormal thyroid function (n = 165).The clinical symptoms and test indicators of the two groups were compared.Results.Among 201 patients with sjogren’s syndrome, 36 patients had abnormal thyroid function (17.9%) and 36 patients with abnormal thyroid function had hypothyroidism.The abnormal renal function, decreased hb, decreased wbc, increased esr, and decreased c4 were more significant in the group with sjogren’s syndrome complicated with abnormal thyroid function, which had significant differences compared with the group with normal thyroid function ( p &lt; 0.05 ).The positive rates of a tg and a tpo in patients with sjogren’s syndrome complicated with thyroid disorders were higher than that in the normal group, and the difference between the two groups was statistically significant ( p &lt; 0.05 ).Conclusion.Patients with sjogren’s syndrome are often associated with hypothyroidism, and these patients may have more severe immune disorders, anemia, leukopenia, and renal involvement.The results show that paying attention to the detection of thyroid function in patients with sjogren’s syndrome may be of positive significance to judge the condition and prognosis.

Journal: Journal of Healthcare Engineering (2021)
Publication types: Research Article;
Characterization of the Immune Cell Infiltration Landscape and a New Prognostic Score in Glioblastoma

Glioblastoma (gbm) is the most aggressive, malignant primary brain tumor, which has abundant tumor-infiltrating immune cells and stroma in the tumor microenvironment (tme).So far, the tme landscape of gbm has not been elucidated.Gbm samples were retrieved from tcga and geo databases.We used estimate and cibersort algorithms to calculate risk score associated with tme, and immune cell infiltration (ici) score of each patient is calculated by pca.Gsea analysis is explored for each subgroup.Finally, the patient prognosis in different ici score subgroup is determined.Two ici clusters are determined in 208 gbm patients, and 207 differentially expressed genes (dges) are found between ici clusters.And then, two gene clusters were determined.Finally, we obtained ici score for each patient using principal component analysis (pca).Patients were divided into high and low ici score subgroups by setting the median as cutoff.Through gsea, we found ecm-receptor interaction, m tor signaling pathway, pathways in cancer, tgf-beta signaling pathway, and other immunosuppressive pathway related genes in the low ici score group.Furthermore, patients with high ici score group have more better prognosis.Targeting the stroma in gbm may be an effective new therapeutic approach, and the ici score is an effective potential prognostic classifier of gbm.

Journal: Journal of Healthcare Engineering (2022)
Publication types: Research Article;
Change in Health-Related Quality of Life in Cochlear Implant Recipients in China

The objective is to assess the benefit of cochlear implants in health-related quality of life among postlingually deaf adults in china.Methods.Seventy-one postlingually deaf adult cochlear implant users in one cochlear implant center in china participated in this study.The hui3 questionnaire as a measurement evaluated their quality of life.A cross-sectional analysis was conducted.Results.Cochlear implant had made statistically significant improvements in quality of life among postlingually deaf adults.The hui3 scores were significantly better in four attributes (hearing, speech, emotion, and pain) after a cochlear implant.A positive correlation between change in hearing and improvement in emotion was significant.The change in pain and improvement in emotion also had a positive correlation.The duration of ha and ci use had no impact on the gain in hui3 scores, and the baseline of hearing and emotion state had an influence on hui3 gain.Conclusion.This study found cochlear implant users had a greatly improved hearing, speech, emotion, and pain, which made statistically significant improvement in quality of life among postlingually deaf adults.There was a statistically significant association between the change of emotion state and improvement in hearing level.We also found a statistically significant correlation between the reduction of feeling in pain and improvement in emotion.The change of quality of life seemed to be influenced by the primary state of emotion and hearing.We believe the measurement hui3 is suitable for these patients in china.

Journal: Journal of Healthcare Engineering (2022)
Publication types: Research Article;
Celecoxib Reverse Invasion and Metastasis of Gastric Cancer through Lnc_AC006548.28-miR-223-LAMC2 Pathway

Celecoxib, a specific cyclooxygenase-2 (cox-2) inhibitor, is a traditional nonsteroidal antipyretic analgesic and anti-inflammatory drug commonly used in clinic, which has inhibitory effect on colorectal cancer, gastric cancer, and other malignant tumors.This study showed that celecoxib could significantly reverse the invasion and metastasis of gastric cancer and improved the pathological changes due to gc.We collected the clinical specimens to analyze the correlation between the expression of lnc_ac006548.28, mi r-223, and lamc2.In the mouse model, celecoxib can slowdown the growth of gc tumor and the occurrence of this effect may depend on lnc_ac006548.28-mi r-223-lamc2 pathway, in vitro transfection, rt-pcr, western blot, cck8, small chamber assay, flow cytometry, and immunohistochemistry to retest the protective effect of celecoxib.Our results showed that celecoxib could reverse invasion and metastasis of gastric cancer through lnc_ac006548.28-mi r-223-lamc2 pathway.

Journal: Computational Intelligence and Neuroscience (2022)
Publication types: Research Article;
Research on the Development Path of Cultural Heritage Information Visualization from the Perspective of Digital Humanities

Art and humanities fields can all benefit from the wide range of digital materials, methodologies, and tools available to researchers.It is the merging of conventional humanities fields like archaeology and history with computer-based tools and techniques as well as other conventional fields like linguistics and literature.Increase in digital cultural heritage data from museums, libraries, and so on requires new modes of analysis rather than standard representations of data.Though the field of online humanities was traditionally seen as a text-based one, researchers in fields like cultural heritage are increasingly using digital representations and visual analysis approaches to study their subjects.A country's cultural heritage (ch) preservation and management are important in preserving and enabling history analysis.There is a growing use of digital and visualization technologies in the documentation and preservation of cultural heritage sites.In this paper, we examine the importance of digital humanities methods, such as 3d reconstruction of cultural heritage and using analysis of variance to develop interactive educational platforms.With the help of the digital framework, ch has been examined and an interactive, open-access network for promoting education, heritage preservation, cultural management, and social responsibilities has been established.

Journal: Mobile Information Systems (2022)
Publication types: Research Article;
Cultivating the Humanistic Quality of Nursing Undergraduates in the Internet Age

Humanistic quality refers to the research ability, knowledge level of the humanities, and the human inner quality of the humanities.The purpose of this paper was to make a research on the cultivation of humanistic literacy of nursing undergraduates in the context of the internet era.This paper first makes a general introduction of the classification of the internet and the definition of humanistic literacy, analyzes the results of two rounds of expert consultation method, and then obtains the current situation of nursing undergraduates through the questionnaire survey of school nursing undergraduates.The experimental results showed that in the current survey situation, the expert support rate of humanistic care is as high as 90%, indicating that humanistic care is especially important for a nursing undergraduate.The total score of humanistic nursing ability of undergraduate nursing students was 127.03, which is in the middle level higher than that of most domestic studies, but lower than that of american nursing students.

Journal: Mobile Information Systems (2022)
Publication types: Research Article;
Discuss the Application of Data Services in Data Health Management of High-Risk Pregnant and Lying-In Women in Smart Medical Care

In order to improve the refined management of hospitals, promote the scientific development of smart hospitals in medical institutions, and solve the problem of data filling and reporting that is increasing year by year in the country, province, and city.Methods.A total of 84 high-risk pregnant women admitted to our hospital from january 2020 to october 2021 were selected and screened for high-risk pregnant women.Risk pregnant women were divided into a routine intervention group and a ds medical group, with 42 cases in each group.High-risk pregnant women in the routine intervention group received routine intervention, and the ds medical group applied data to serve smart medical services on the basis of routine intervention.The scores of self-care, anxiety, and depression were compared between the two groups, the coping styles were analyzed, the satisfaction rate and incidence of adverse conditions of the high-risk puerperae were recorded, and the delivery methods of the two groups were compared.Results.After the intervention, the activities of daily living, follow-up, fetal monitoring, and self-protection behaviors in the ds medical group were higher than those in the routine intervention group, and the difference was statistically significant ( p &lt; 0.05 ).The scores of anxiety and depression in the group were lower, with statistical significance ( p &lt; 0.05 ); after the intervention, the scores of negative coping styles in the ds medical group were lower than those in the conventional intervention group, while the scores for positive coping styles were higher than those in the conventional intervention group; the ds medical group had higher risk.The satisfaction of pregnant women was significantly higher than that of the routine intervention group, and the difference was statistically significant ( p &lt; 0.05 ); the overall incidence of adverse maternal outcomes among high-risk pregnant women in the ds medical group was lower than that of the routine intervention group, and the difference was not statistically significant ( p &gt; 0.05 ).Compared with the routine group, the ds medical group had a higher number of vaginal deliveries and a lower number of cesarean deliveries, and the difference was statistically significant ( p &lt; 0.05 ).Conclusion.The application of data services in a smart medical high-risk maternity-related data management platform enables the promotion of high-risk pregnant women’s self-care behaviors and improves negative emotions, enables them to cooperate in delivery with positive behaviors, and reduces the number of cases of cesarean delivery.

Journal: Scanning (2022)
Publication types: Clinical Study;
Effect of Rehabilitation Physical Training on PE Teaching Sports Injury under Ultrasonic Examination

In order to solve the problem of the effect of rehabilitation physical training on physical education teaching injury, a method based on ultrasonic examination of rehabilitation physical training on physical education teaching injury effect observation method is proposed.In this method, the isomed isokinetic muscle strength test, the body shape test, the balance ability test, the lower limb explosive power test, and other methods are used to evaluate the knee joint of patients systematically, and the specific rehabilitation physical training plan is formulated to achieve the treatment purpose.The experimental results show that after the targeted training, a series of indicators on the affected side increase significantly: the power increases by 45.6%, the force increases by 8.3%, and the speed increases by 38.7%.It is concluded that the muscle strength, shape, balance ability, and lower limb explosive power of patients are significantly improved, which lays a solid foundation for athletes to recover smoothly and achieve good competition results.

Journal: Scanning (2022)
Publication types: Research Article;
Effects of Pelvic Floor Muscle Massage on the Pregnancy Outcome of Frozen Embryo Transfer in Patients with Thin Endometrium

To observe the effects of pelvic floor muscle mass on the priority outcome of frozen embryo transfer in patients with thin endometrium.Methods.The patients who were prepared for freeze-thaw embryo transfer were randomly divided into the study group and control group.Both groups of patients began to take estradiol valerate tablets 3 mg on the third day of menstrual cycle and added progesterone for luteal support after 14 days.Both groups selected high-quality embryos for embryo transfer on the day of embryo transfer.The basic information, embryo transfer, intimal thickness, intimal type, clinical pregnancy rate, and early abortion rate of the two groups were compared.Results.The intimal thickness of patients in the control group and the study group on the second day of menstruation was ( 0.49 ± 0.03 ) and ( 0.45 ± 0.02 ) and that before progesterone was ( 1.17 ± 0.03 ) and ( 1.20 ± 0.04 ), respectively ( p &lt; 0.05 ).At the same time, the number of excellent embryos in the study group was significantly higher than that in the control group ( p &lt; 0.05 ), but there was no significant difference in the number of transplants between the two groups ( p &gt; 0.05 ).The proportion of intimal blood flow of type iii + ii in the study group was significantly higher than that in the control group ( p &lt; 0.05 ).The main adverse pregnancy outcomes of the whole group included biochemical pregnancy, early abortion, and ectopic pregnancy.The incidence of biochemical pregnancy in the control group and the study group was 63.3% (38/60) and 40.0% (24/60), respectively.The incidence of biochemical pregnancy in the control group was significantly higher than that in the study group, but there was no significant difference in the incidence of early abortion and ectopic pregnancy between the two groups ( p &gt; 0.05 ).Conclusion.Pelvic floor muscle massage can improve endometrial thickness and subendometrial blood flow, so as to improve the pregnancy rate of frozen thawed embryo transfer patients.

Journal: Computational and Mathematical Methods in Medicine (2022)
Publication types: Clinical Study;
Career Exploration and College Students’ Career Adaptability: The Mediating Role of Future Work Self-Salience and Moderating Role of Perceived Teacher Support

Based on the theory of career construction, a moderated mediation model is built in this paper to probe into the relationship between career exploration and career adaptability, discussing the mediating role of future work self-salience and the moderating role of perceived teacher support.With the research sample of 1101 unemployed college students, spss and amos, a structural equation modeling software is employed for modeling so as to perform the linear regression analysis of three-stage data.The research findings are about four aspects; to start with, students’ career exploration is positively related to career adaptability; besides, future work self-salience plays a partial role in mediating between college students’ career exploration and career adaptability; next, perceived teacher support positively moderates two kinds of positive relationship: one is between career exploration and future work self-salience of college students and the other between their future work self-salience and career adaptability.Lastly, the indirect effect of the future work self-salience between career exploration and career adaptability is moderated by perceived teacher support.As opposed to a lower level of teacher support, this moderated mediating effect is significant only at a higher level of perceived teacher support.This research clarifies the link between career exploration and career adaptability through future work self-salience and practical enlightenment about how to enhance career adaptability via perceived teacher support.

Journal: Discrete Dynamics in Nature and Society (2021)
Publication types: Research Article;
Association between Interleukin-4-590CT Polymorphism and the Susceptibility to Asthma: A Meta-Analysis of Case-Control Study

This study was aimed to investigate the relationship between the interleukin-4-590c &gt; t gene polymorphism and the susceptibility to asthma by meta-analysis.To explore the underlying relationship between the polymorphism of il-4-590c &gt; t and the susceptibility to asthma, this study systematically retrieved the literature including cohort studies and case-control studies published before june 2019 in pub med, embase, and cochrane library.Data on the odds ratio (or) and 95% confidence interval (ci) of the literature were included in the relative studies.Subsequently, the included data were weighted by an inverse variance and then analyzed by the fixed or random effects model.Overall, 818 asthma patients and 831 healthy individuals participated in the 8 independent case-control studies in the current meta-analysis.There was no correlation between il-4-590c &gt; t tt genotype and the increased susceptibility to asthma (dominant model: or = 1.31, 95% ci = 0.68–2.53).Subgroup analysis by ethnicity showed no significant results in the asians (or = 1.28, 95% ci = 0.24–6.80); however, il-4-590c &gt; t tt genotype significantly elevated the susceptibility to asthma in the caucasians (or = 1.43, 95%ci = 1.03–1.98).Meanwhile, subgroup analysis was performed by source of control.A statistically significant result was found in the population-based control group (or = 1.33, 95% ci = 1.01–1.76), but not in the hospital-based control group (or = 1.22, 95% ci = 0.27–5.46).The results demonstrated that il-4-590c &gt; t tt genotype could significantly enhance the susceptibility to asthma in caucasians without increasing that in asian populations.However, it still required a large sample of high-quality studies in multicentral hospital to further confirm its reliability.

Journal: Journal of Healthcare Engineering (2022)
Publication types: Meta-Analysis;
Color Image Landscape Photo Hand-Painted Effect Evaluation with PFA Algorithm

With the continuous development of society and economy, diversified presentation and publicity of landscape are becoming more and more popular among the public, such as using color pictures to display multimedia publicity videos or app, we chat public accounts, and other new media.There are various ways of expression.Against the limitations of color image landscape, this article introduced the pfa algorithm, during the experiment of hand-painted landscape pictures, the effect of color hand-painted images is evaluated by using the coordination degree of natural target detection scene, and the corresponding image evaluation index values are obtained for effective analysis, and the prediction model is established.The simulation results show that the pfa algorithm is effective and can support the evaluation of the hand-painted effect of color landscape photos.

Journal: Advances in Multimedia (2021)
Publication types: Research Article;
Drought Assessment Based on Data Fusion and Deep Learning

Drought is a major factor affecting the sustainable development of society and the economy.Research on drought assessment is of great significance for formulating drought emergency policies and drought risk early warning and enhancing the ability to withstand drought risks.Taking the yellow river basin as the object, this paper utilizes data fusion, copula function, entropy theory, and deep learning, fuses the features of meteorological drought and hydrological drought into a drought assessment index, and establishes a long short-term memory (lstm) network for drought assessment, based on deep learning theory.The results show that (1) after extracting the features of meteorological drought and hydrological drought, the drought convergence index (dci) built on the fused features by copula function can accurately reflect the start and duration of the drought; (2) the drought assessment indices were effectively screened by judging the causality of the drought system, using the transfer entropy; (3) drawing on the idea of deep learning, lstm for drought assessment, which was established on dci and the drought assessment factors, can accurately assess the drought risks of the yellow river basin.

Journal: Computational Intelligence and Neuroscience (2022)
Publication types: Research Article;
Causes and Preventive Measures of Sports Injuries in Physical Fitness Tests in Colleges and Universities Based on Biological Characteristics

Biological characteristics refer to the morphological and physiological characteristics exhibited by individual organisms.The indicators of individual biological characteristics mainly include physical indicators such as height, weight, chest circumference, and health-related physical indicators such as blood pressure, grip strength, and vital capacity.This article mainly introduces the cause analysis and preventive measures of a physical fitness test in colleges and universities based on biological characteristics and intends to provide ideas and directions for the cause analysis and preventive measures of a physical fitness test in colleges and universities.This paper proposes a research method for the cause analysis and preventive measures of sports injuries in college physical fitness tests based on biological characteristics.Research experiments on the cause analysis and preventive measures of sports injuries in the physical fitness test of colleges and universities.The experimental results in this paper show that the most frequent cause of sports injuries among boys is lack of self-protection awareness, with a probability of 24.24%; among girls, the most frequent cause of sports injuries is insufficient flexibility, with a probability of 22.86%.

Journal: Journal of Healthcare Engineering (2021)
Publication types: Research Article;