syedzayyan/paper_mill_benchmark huggingface dataset:
Survey on the Presence of Bacterial, Fungal and Helminthic Agents in Off-Leash Dog Parks Located in Urban Areas in Central-Italy.

Off-leash dog parks are designated public spaces where dogs can move freely, under their owners' supervision.These areas, allowing animals to socialize and move freely, are fundamental for dogs' welfare.However, different pathogens, even zoonotic, may be excreted by the attending animals and contaminate the environment.The aim of the present study was to verify the occurrence of bacterial, fungal and parasitic pathogens in off-leash dog parks located in florence (central italy).Between march and may 2019, 83 fecal samples, 43 soil samples and 23 water samples (from fountains and puddles) collected from 26 off-leash fenced areas were examined.Fecal samples scored positive for yersiniaspp.(n= 7),listeria innocua(n= 4),toxocara&nbsp;caniseggs (n= 2) and ancylostoma caninum/uncinaria stenocephalaeggs (n= 1).Keratinophilic geophilic fungi (mostly microsporum gypseum /a.Incurvatum) were recovered from 43 soil samples belonging to 23 out of 26 parks, along with microsporum canisin a single case.protothecaspp.Was never isolated from water samples, while trichosporonsp.Was cultured in two cases, alone and in association with geotrichum candidum.These results show that dogs did not act as important carriers for the investigated bacterial and parasitic pathogens, although examined areas may represent a risk for the spreading of some dermatophytoses to both pets and their owners.Periodical examinations to assess the main bacteriological, parasitological and mycological pathogens in different samples collected in off-leash dog parks should be carried out in a one-health perspective.

Journal: Animals : an open access journal from MDPI (2021)
Publication types: Journal Article
Superconducting-Magnet-Based Faraday Rotation Spectrometer for Real Time in Situ Measurement of OH Radicals at 106Molecule/cm3Level in an Atmospheric Simulation Chamber.

Atmospheric simulation chambers play vital roles in the validation of chemical mechanisms and act as a bridge between field measurements and modeling.Chambers operating at atmospheric levels of oh radicals (106-107molecule/cm3) can significantly enhance the possibility for investigating the discrepancies between the observation and model predications.However, few chambers can directly detect chamber oh radicals at ambient levels.In this paper, we report on the first combination of a superconducting magnet with midinfrared faraday rotation spectroscopy (frs) for real time in situ measurement of the oh concentration in an atmospheric simulation chamber.With the use of a multipass enhanced frs, a detection limit of 3.2 × 106oh/cm3(2σ, 4 s) was achieved with an absorption path length of 108 m.The developed frs system provided a unique, self-calibrated analytical instrument for in situ direct measurement of chamber oh concentration.

Journal: Analytical chemistry (2018)
Publication types: Journal Article;Research Support, Non-U.S. Gov't
Low-density lipoprotein apheresis is associated with removal of SARS-CoV-2 antibodies.

Low-density lipoprotein apheresis is not specific to lipoproteins but removes immunoglobulins as well.It remains elusive, whether protective sars-co v-2 antibodies after vaccination from covid-19 are eliminated as well.Methods a cross-sectional case-control study on 55 patients undergoing weekly lipoprotein apheresis and 21 patients with comparable comorbidities and epidemiology not undergoing apheresis.Sars-co v-2 ig g was assessed in all patients prior to apheresis and in 38 patients both before and after apheresis.Results sars-co v-2 ig g concentrations before a session of lipoprotein apheresis were comparable to control patients not undergoing apheresis(1727 iu/ml, iqr 365-2500) vs.1652 iu/ml,(iqr408.8-2500), p = 0.78).Sars-co v-2 ig g concentrations were reduced by lipoprotein apheresis from 1656 iu/ml(iqr 540.5-2500) prior to 1305 iu/ml (iqr 449-2500) afterwards(p < 0.0001).Conclusion lipoprotein apheresis removes sars-co v-2 ig g.The average elimination rate was 21.2%.In the present population of patients undergoing apheresis once weekly, however, the elimination did not lead to inferior concentrations compared to patients not undergoing lipoprotein apheresis.

Journal: Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy (2022)
Publication types: Journal Article
Determination of Si/graphite anode composition for new generation Li-ion batteries: a case study.

Silicon with the properties of high capacity capability, moderate working potential, environmental sensitivity, and existence are the highly promising anode materials for lithium-ion batteries.Silicon anodes have disadvantageous properties and advantages like 300% volume change during lithium insertion and extraction process that can result in capacity fading and a shorter lifetime of the battery.In the literature, different optimizations of silicon with different nanomaterials or composite materials, in different ratios, and with different binders and different procedures have been studied.The physical mixing of silicon with carbon provides a good performance by combining the high lithium storage capacity of the silicon and the good mechanical and conductive properties of carbon.Binders are one of the other factors affecting the performance of the si/c anodes.In this study, different ratios of silicon/graphite combinations were tested.The si/c hybrid material provides an advantageous and efficient use for innovative lithium-ion anodes and available lithium-ion battery technology when the si/c match performs a suitable combination of two material properties, such as the high lithium storage capacity of silicon and the conductive properties of carbon.This study is aimed to improve the performance of the cell by changing the amount of active material and polymer in the electrode by finding the most appropriate amount of active substance and binder polymer ratio in the electrode.The electrochemical result of the composition, which compensates for the problems caused by the volume expansion of the silicon by using less silicon, showed higher capacitive properties, as it exhibits better adhesion among these compositions with a higher binder ratio.This study resulted in more than 1000 m ah/g specific capacity after 100 cycles at c/3 rate and structural characterization of the samples before and after cycling provided information about the electrode content.

Journal: Turkish journal of chemistry (2022)
Publication types: Journal Article
Characteristics of Cancers in Adolescents and Young Adults Compared with Those in Adults in Their 60s: A Single-Center Experience.

Introduction cancer is one of the main causes of death among adolescents and young adults (ayas) aged 15-39 years.The improvement in overall 5-year survival in aya cancer patients was far below than that of adult cancer patients.The purpose of this study was to clarify the features of cancer in ayas by comparing them with those of controls.Methods patients in the cancer registry of the university of tsukuba hospital between 2007 and 2017 (median age, 65 years) were included in this study.We used patients between the ages of 64 and 66 years as controls.We then obtained the age at diagnosis, sex, primary site, and pathological type.Results among 27,281 cancer patients in the registry between 2007 and 2017, 1,947 (7.1%) patients were categorized into the aya group, and 2,354 into the control group.Among men in the aya group, central nervous system (cns) tumors accounted for 22.7% of all cancers, followed by germ cell tumors, 22.5%, and hematopoietic malignancies, 12.5%.Among women in the aya group, cervical cancer accounted for 35.9% of all cancers, followed by breast cancer, 14.6%, and cns tumors, 11.6%.The proportion of specific cancer types relative to all cancers in the cns, thyroid, adrenal glands, germ cells, cervix uteri, hematopoietic tissues, and sarcomas was higher in the aya group than that in the control group.Conclusion the present results for ayas were in sharp contrast to those for adult cancers and may be related to different modes of pathogenesis in ayas.The identification of high-risk groups of these tumors in the aya generation is crucial for prevention and early detection and will be a major topic for future research.While most of adult cancers are treated independently by each medical department, aya cancers need to be treated in collaboration with experts from several departments.It is desirable to address the issues involved in applying treatments established for adult cancers to aya cancers on a cancer-by-cancer basis.

Journal: Oncology (2022)
Publication types: Comparative Study;Journal Article
Occlusion Pressure of the Thoracic Duct in Fontan Patients With Lymphatic Failure: Does Dilatation Challenge Contractility?

The fontan circulation challenges the lymphatic system.Increasing production of lymphatic fluid and impeding lymphatic return, increased venous pressure may cause lymphatic dilatation and decrease lymphatic contractility.In-vitro studies have reported a lymphatic diameter-tension curve, with increasing passive stretch affecting the intrinsic contractile properties of each thoracic duct segment.We aimed to describe thoracic duct occlusion pressure and asses if thoracic duct dilation impairs contractility in individuals with a fontan circulation and lymphatic failure.Methods central venous pressure and thoracic duct measurements were retrospectively collected from 31 individuals with a fontan circulation.Thoracic duct occlusion pressure was assessed during a period of external manual compression and used as an indicator of lymphatic vessel contractility.Measurements of pressure were correlated with measurements of the thoracic duct diameter in images obtained by dynamic contrast-enhanced mr lymphangiography.Results the average central venous pressure and average pressure of the thoracic duct were 17 mm hg.During manual occlusion, the thoracic duct pressure significantly increased to 32 mm hg.The average thoracic duct diameter was 3.3 mm.Thoracic duct diameter correlated closely with the central venous pressure.The rise in pressure following manual occlusion showed an inverse correlation with the diameter of the thoracic duct.Conclusion higher central venous pressures are associated with increasing diameters of the thoracic duct.When challenged by manual occlusion, dilated thoracic ducts display a decreased ability to increase pressure.Dilatation and a resulting decreased contractility may partly explain the challenged lymphatic system in individuals with a fontan circulation.

Journal: World journal for pediatric & congenital heart surgery (2022)
Publication types: Journal Article;Research Support, Non-U.S. Gov't
Dermatoscopic Features of Onychomycosis and its Correlation with Nail Plate Potassium Hydroxide Mount (KOH), Culture, and Periodic Acid Schiff Stain (PAS) in North East India.

Context dermatoscopy has been used recently for identifying the specific features of onychomycosis.Very few studies have used it as a diagnostic tool.Our study highlights the specific patterns in different clinical types of onychomycosis and the novel features that have never been reported previously.Aims to study the dermatoscopic patterns in patients with onychomycosis and determine the sensitivity, specificity, positive, and negative predictive values of the different features.Study design a cross-sectional study.Materials and method dermatoscopic picture using dinolite video dermatoscope was taken in patients diagnosed with onychomycosis either with a positive koh, culture, and/or pas.Result a total of 80 patients were included.Onychomycosis was identified in 68 individuals.Clinically, 73.52% presented with distal lateral subungual onychomycosis (dlso) and 26.47% had total dystrophic (td).Pas was positive in 85.29% of patients, koh in 75%, and culture in 66.17%.trichophytonspecies were isolated in 53.33%, whereas candidaspecies in 40% of patients.Dermatoscopic features were seen in all 68 patients (100%).The most common finding in decreasing order includes spike pattern, ruin appearance, distal irregular terminations (dit), longitudinal striations, chromonychia, focal homogeneous opacities, microsplitting, and uniform homogeneous pattern.Three novel patterns were observed: homogeneous opacity with a-z pattern border, microsplitting in a christmas tree pattern, and focal homogeneous opacities.Conclusion to our knowledge, this is the first study conducted in northeast india where dermatoscopy was used as a diagnostic tool and it was found to have the highest sensitivity.New features that have not been described before have been identified.

Journal: Indian journal of dermatology (2021)
Publication types: Journal Article
Use of tandem carbon microfiber columns for on-line fractionation strategy of reducing ion suppression effects in electrospray ionization-mass spectrometry.

As we all know, the complexity and diversity of complex sample are confronting with challenge of high-sensitive mass spectrometry analysis, especially direct mass spectrometry.The work proposed a two-dimensional carbon microfiber fractionation (2dμcfs) system for the reduction of ion suppression effects in electrospray ionization mass spectrometry (esi-ms).The 2dμcfs system can on-line fractionated the complex sample into strong-polar, medium-polar and weak-polar fractions for sequential ms analysis.Direct analysis brings about the strong ion suppression effect up to 85%, but the fractionated analysis of 2dμcfs system can distinctly reduce the ion suppression effect to less than 43%, even close to none.And the fractionated analysis not only decrease the number of analytes of direct analysis, but also narrows down the polarity range of analytes within the droplets of esi, contributing to the homogeneous distribution to reduce the ion suppression effect.As an example, the 2dμcfs system coupled with tandem mass spectrometry (ms/ms) was applied for fractionated analysis of radix puerariae extract in 4.5 min.Compared with direct ms/ms, the 2dμcfs-ms/ms shows the lower ion suppression and the more ionic species (m/z).In addition, and most of ionic species detected by the 2dμcfs-ms/ms, are the same as those by hplc ms/ms.Furthermore, the 2dμcfs-ms/ms exhibit the good analysis repeatability of real sample with the rsds less than 10.32% (intra-day), 7.12% (inter-day) and 14.28% (inter-batch of cfs and acfs).The carbon fibers (cfs) and active carbon fibers (acfs) columns, as the key parts, are conducive to achieve on-line fractionation of compounds based on the difference of polarity.The 2dμcfs system has the merits of on-line, speediness, low-pressure and recycle.More importantly, such fast and high-throughput method is advantageous for comprehensive screening of complex samples in drug, clinical, environment and plant.

Journal: Journal of chromatography. A (2022)
Publication types: Journal Article
Shaping polyelectrolyte composites for heavy metals adsorption from wastewater: Experimental assessment and equilibrium studies.

Design of core/shell composite microparticles for loading/release of organic/inorganic pollutants is of great interest in wastewater treatment.As compared to the classic layer-by-layer strategy, the new approach presented in this study introduced higher organic shell amounts in one-pot deposition step, with less material and energy consumption and lack of toxic by-products formation.Herein, one weak polycation (polyethyleneimine) and two weak polyanions were directly deposited onto silica surface through precipitation of an in-situ formed interpolyelectrolyte coacervate, followed by selective crosslinking with glutaraldehyde and extraction of polyanion chains, confirmed by electrokinetic measurements and ftir spectra of composites.Twelve composite sorbents were synthesized and tested for adsorption of cadmium, as model heavy metal ion.It was demonstrated that the high sorption occurred onto four newly synthesized composites which is correlated to the deposited shell amount, dependent on the deposition method, polyanion nature and crosslinking ratio.The cd2+sorbed amount increased with the polyelectrolyte deposited amount and with the accessibility toward active sorption site, less cross-linked composite shells sorbing higher amounts as compared to strong cross-linked shells, the molar ratio [active site]:[cd2+] ranging from 16:1 to 26:1.The best fitting of four isotherm (langmuir, freundlich, sips and toth) and four kinetics (pseudo-first order, pseudo-second order, modified freundlich and elovich) models was assessed by the sum of normalized errors, based on different nonlinear regression error functions, and by the hannah-quinn information criterion.In general, the best agreement with the experimental data was found for toth isotherm and the pseudo-second order kinetic model.Efficient regeneration of the sorbents was possible at least three times.The competitive effect of pb2+and ni2+ions was also studied in simulated and real systems.Silica composite sorbents with polyethyleneimine chains as major component of the shell could be very promising in wastewater treatment processes.

Journal: Journal of environmental management (2022)
Publication types: Journal Article
Individual and community-level risk for COVID-19 mortality in the United States.

Reducing covid-19 burden for populations will require equitable and effective risk-based allocations of scarce preventive resources, including vaccinations1.To aid in this effort, we developed a general population risk calculator for covid-19 mortality based on various sociodemographic factors and pre-existing conditions for the us population, combining information from the uk-based open safely study with mortality rates by age and ethnicity across us states.We tailored the tool to produce absolute risk estimates in future time frames by incorporating information on pandemic dynamics at the community level.We applied the model to data on risk factor distribution from a variety of sources to project risk for the general adult population across 477 us cities and for the medicare population aged 65 years and older across 3,113 us counties, respectively.Validation analyses using 54,444 deaths from 7 june to 1 october 2020 show that the model is well calibrated for the us population.Projections show that the model can identify relatively small fractions of the population (for example 4.3%) that might experience a disproportionately large number of deaths (for example 48.7%), but there is wide variation in risk across communities.We provide a web-based risk calculator and interactive maps for viewing community-level risks.

Journal: Nature medicine (2021)
Publication types: Journal Article;Research Support, Non-U.S. Gov't
Open waste burning contrary to other air pollution-related perceptions and practices in Pokhara, Nepal.

A cross-sectional survey was conducted in pokhara, nepal between february 3 and 12, 2018 to determine whether air pollution-related perceptions led to a reduction in open burning of waste.Of the 394 people interviewed, 58.3% expressed their concerns about health risks due to air quality.Multiple logistic regression identified that perceived health risk (aor, 5.70; 95% ci, 3.44-9.45) was a significant predictor of refraining from actions that increase air pollution.While 90.6% of people used trash lorry to dispose domestic waste, 40.6% treated domestic waste by open burning.Unexpectedly, a high level of perceived health risks (aor 1.72; 95% ci, 1.02-2.91), a high rated contribution of open waste burning to air pollution (aor, 1.71; 95% ci, 1.06-2.78), and frequent refraining from actions that increase air pollution (aor, 1.78; 95% ci, 1.08-2.94) were significant predictors of frequent open waste burning.The results implied urgent need for improvement in waste collection efficiency and raising awareness of health risks of open waste burning.

Journal: Archives of environmental & occupational health (2022)
Publication types: Journal Article;Research Support, Non-U.S. Gov't
Transitioning from pediatric to adult healthcare: exploring the practices and experiences of care providers.

Context: youth with complex care needs (ccn) experience complex health conditions, many of which were once seen as fatal and are now increasingly associated with survival into adulthood.As a result, more youth are transitioning from pediatric to adult healthcare as they approach adulthood.Current transition practices, when present, are disorganized, resulting in health status deterioration and complications due to unmet needs.Objective: the purpose of this study is to develop a broader understanding of the current transition practices and experiences, as well as recommendations of care providers in the support of youth with ccn as they transition from pediatric to adult healthcare.Study design: this study uses a qualitative descriptive design.The data collected was analyzed using inductive thematic analysis following the six phases outlined by braun and clarke (2006).Population studied: a purposeful sample of 15 primary care providers (pcp), specialists, and subspecialists who support youth in the transition from pediatric to adult healthcare were interviewed using a semi-structured interview guide.Setting: the study spanned the province of new brunswick and included pediatric providers from the iwk health centre in nova scotia.Results: the findings from this research demonstrate a shortage of care providers and lack of community services available for youth with ccn who move into adult healthcare services.Specifically, due to the significant amount of primary care pediatricians provide youth during childhood, improved access to pcps was a recommendation.Moreover, participants indicated that a designated transition coordinator can enhance the transition process for the youth and stakeholders involved in their care.Conclusion: the results of this study can potentially improve transition practices and policies for primary care practice, and guide future research in this area.

Journal: Annals of family medicine (2022)
Publication types: Journal Article