syedzayyan/paper_mill_benchmark huggingface dataset:
Aneurysmal Bone Cyst Plus Lesions: A Case Report and a Literature Review.

The intraosseous osteolytic lesions mainly involving the metaphyseal region of vertebrae and long bones were diagnosed as aneurysmal bone cysts (abcs).Further, an abc was known as an ossifying hematoma.It is considered an expanding osteolytic lesion consisting of blood-filled spaces of variable sizes separated by connective tissue septa containing trabeculae of osteoid tissue and osteoclast giant cells.It is frequently reported to involve long bones; however, only 1.9% prevalence is seen in jaw bones.It represents a very small percentage of all non-odontogenic tumors.Abc shows variations in age prevalence and its clinical presentation may be challenging to the surgeon.In addition, abc may occur in association with other primary bone pathologies like ossifying fibroma, fibrous dysplasia, and giant cell tumor; such entities are known as abc plus lesions.Here we present a classic case of abc plus lesion.

Journal: Cureus (2022)
Publication types: Case Reports;Journal Article
One Health training needs for Senegalese professionals to manage emerging public health threats.

Global health trends, marked by increasing epidemics and pandemics, call for enhanced human resource preparedness to prevent and respond to emerging and future health problems.Indeed, according to the world organization for animal health (woah), at least 75% of the pathogens responsible for emerging and re-emerging human infectious diseases originate from animals.These health problems involve environmental, economic and social factors.Because of their multidimensional nature, addressing these health problems requires the adoption of a one health approach.To achieve this, training of human resources is a priority.This descriptive cross-sectional study was conducted from september 12 to 22, 2021 in 6 regions of senegal, namely, dakar, thiès, diourbel, kaolack, saint-louis, and ziguinchor.Questionnaires were administered online and in person to 217 professionals in human, environmental, animal health and agriculture.Data were statistically processed, and bivariate analyses enabled a better correlation between training needs for professionals according to their occupational group.The survey sample was 64% male and 36% female.More than half of the professionals surveyed (53.5%) had less than 10 years of experience.Human health workers were the most represented (46%), followed by animal health workers (34%) and environmental workers (16%).Agriculture, fisheries, and food security were weakly represented.Few had received training in the one health approach and entry-level one health skills predominated.The one health competencies in which professionals want to build capacity differ by sector.Globally, public health and epidemiology, health risk management, basic of one health concepts, animal health and biotechnology are the priorities.The development of training programs could then enable these expressed needs to be addressed.

Journal: Science in One Health (2022)
Publication types: Journal Article
Geographic accessibility to health facilities predicts uptake of community-based tuberculosis screening in an urban setting.

S annually, more than 30% of individuals with tuberculosis (tb) remain undiagnosed.We aimed to assess whether geographic accessibility measures can identify neighborhoods that would benefit from tb screening services targeted toward closing the diagnosis gap.Methods we used data from a community-based mobile tb screening program in carabayllo district, lima, peru.We constructed four accessibility measures from the geographic center of neighborhoods to health facilities.We used logistic regression to assess the association between these measures and screening uptake in one's residential neighborhood versus elsewhere, with quasi-information criterion values to assess the association.Results we analyzed the screening locations for 25,000 carabayllo residents from 49 neighborhoods.Pedestrian walk time was preferable to euclidean distance or vehicular time in our models.For each additional 12 minutes walking time between the neighborhood and the health facility, the odds of residents using tb screening units located in their neighborhoods increased by 50% (95% ci: 26%-78%).Females had 9% (95% ci: 3%-16%) increased odds versus males of using a screening unit in their own neighborhood.Conclusion placing mobile tb screening units in neighborhoods with longer pedestrian time to access health facilities could benefit individuals who face more acute access barriers to health care.

Journal: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases (2022)
Publication types: Journal Article
CO2emissions, income inequality, and country risk: some international evidence.

This research explores the effects of income inequality and country risk on co2emissions and examines whether the effects change across countries with different development stages or income levels.A new panel quantile regression approach is used to conduct a comprehensive analysis of the impacts of affecting factors on co2emissions at various quantiles, while addressing econometric challenges such as endogeneity and heterogeneity.From a global perspective, we can conclude that the marginal impact of inequality on emissions drops constantly with decreasing country risk at 10th to 50th quantiles, which even performs negative, whereas at the other quantiles, the marginal impact of inequality always remains negative.When we focus on the different income groups, the nexus of inequality emissions is negative first and then positive with decrease of country risk in low-income countries but shows no significant in low-middle- and upper-middle-income countries.Additionally, we validate the detrimental impact of income inequality in upper-income countries.Besides, country risk adversely moderates the nexus of inequality and emissions in low- and upper-income countries.Empirical results confirm that the nexus of inequality emissions lies in country risk, income level, and existing emission degree.These findings provide some important recommendations for policy-makers.

Journal: Environmental science and pollution research international (2022)
Publication types: Journal Article
A nomogramic model based on clinical and laboratory parameters at admission for predicting the survival of COVID-19 patients.

Covid-19 has become a major global threat.The present study aimed to develop a nomogram model to predict the survival of covid-19 patients based on their clinical and laboratory data at admission.Methods covid-19 patients who were admitted at hankou hospital and huoshenshan hospital in wuhan, china from january 12, 2020 to march 20, 2020, whose outcome during the hospitalization was known, were retrospectively reviewed.The categorical variables were compared using pearson's χ2-test or fisher's exact test, and continuous variables were analyzed using student's t-test or mann whitney u-test, as appropriate.Then, variables with a p-value of ≤0.1 were included in the log-binomial model, and merely these independent risk factors were used to establish the nomogram model.The discrimination of the nomogram was evaluated using the area under the receiver operating characteristic curve (auc), and internally verified using the bootstrap method.Results a total of 262 patients (134 surviving and 128 non-surviving patients) were included in the analysis.Seven variables, which included age (relative risk [rr]: 0.905, 95% confidence interval [ci]: 0.868-0.944; p < 0.001), chronic heart disease (chd, rr: 0.045, 95% ci: 0.0097-0.205; p < 0.001, the percentage of lymphocytes (lym%, rr: 1.125, 95% ci: 1.041-1.216; p = 0.0029), platelets (rr: 1.008, 95% ci: 1.003-1.012; p = 0.001), c-reaction protein (rr: 0.982, 95% ci: 0.973-0.991; p < 0.001), lactate dehydrogenase (ldh, rr: 0.993, 95% ci: 0.990-0.997; p < 0.001) and d-dimer (rr: 0.734, 95% ci: 0.617-0.879; p < 0.001), were identified as the independent risk factors.The nomogram model based on these factors exhibited a good discrimination, with an auc of 0.948 (95% ci: 0.923-0.973).Conclusions a nomogram based on age, chd, lym%, platelets, c-reaction protein, ldh and d-dimer was established to accurately predict the prognosis of covid-19 patients.This can be used as an alerting tool for clinicians to take early intervention measures, when necessary.

Journal: BMC infectious diseases (2020)
Publication types: Journal Article
Successfully treated bilateral renal fungal balls with continuous Anidulafulgin irrigation.

A 73-year-old man with a history of type 2 diabetes mellitus, nephrolithiasis, and recurrent urinary tract infections caused by candida glabratawas admitted to our hospital.Urosepsis was diagnosed and c.Glabratawas isolated from urine and blood cultures.Computed tomography intravenous pyelography (ct-ivp) revealed bilateral filling defects caused by renal fungal balls.Treatment initially comprised intravenous anidulafungin coupled with continuous local anidulafungin irrigation via bilateral nephrostomy tubes, which was followed by high-dose oral fluconazole.This regimen successfully eradicated the c.Glabratain follow-up cultures.

Journal: Urology case reports (2021)
Publication types: Case Reports;Journal Article
The relationship between college students' campus sexual health resource utilization and self-reported STI testing: Findings from an undergraduate probability survey.

To examine the prevalence of student utilization of campus sexual health resources and their association with sexually transmitted infection (sti) testing.participants:undergraduate students (n= 7020) at a large midwestern university completed a confidential online survey in 2015.methods:a probability-based sample of undergraduate students completed a cross-sectional online survey.results:commonly accessed sexual health resources were student orientation activities about sexual assault or rape, sexuality/gender classes, gender and sexual orientation panels, class panels on sexual assault, birth control and sti presentations, and having joined a sexuality-related student organization.Campus sexual health resource utilization was significantly associated with greater sti testing since college.Gender, race, class level, enrollment status, sexual orientation, timing of last sexual event, and perceived sti risk were significantly associated with sti testing in college.conclusions:campus sexual health resources play an important role in student sexual health promotion.

Journal: Journal of American college health : J of ACH (2022)
Publication types: Journal Article
Ecological study of cave nectar bats reveals low risk of direct transmission of bat viruses to humans.

Bats are reservoirs of various viruses.The widely distributed cave nectar bat (eonycteris spelaea) is known to carry both filoviruses and coronaviruses.However, the potential transmission of theses bat viruses to humans is not fully understood.In this study, we tracked 16e.Spelaeabats in mengla county, yunnan province, china, using miniaturized gps devices to investigate their movements and potential contact with humans.Furthermore, to determine the prevalence of coronavirus and filovirus infections, we screened for the nucleic acids of the měnglà virus (mlav) and two coronaviruses (gccdc1-co v and hku9-co v) in anal swab samples taken from bats and for antibodies against these viruses in human serum samples.None of the serum samples were found to contain antibodies against the bat viruses.The gps tracking results showed that the bats did not fly during the daytime and rarely flew to residential areas.The foraging range of individual bats also varied, with a mean cumulative nightly flight distance of 25.50 km and flight speed of up to 57.4 km/h.Taken together, these results suggest that the risk of direct transmission of gccdc1-co v, hku9-co v, and mlav from e.Spelaeabats to humans is very low under natural conditions.

Journal: Zoological research (2022)
Publication types: Journal Article
Spatiotemporally Explicit Mapping of Built Environment Stocks Reveals Two Centuries of Urban Development in a Fairytale City, Odense, Denmark.

The urban built environment stocks such as buildings and infrastructure provide essential services to urban residents, and their spatiotemporal dynamics are key to the circular and low-carbon transition of cities.However, spatiotemporally explicit characterization of urban built environment stocks remains hitherto limited, and previous studies on fine-grained mapping of built environment stocks often focus on an urban area without consideration of temporal dynamics.Here, we combined the emerging geospatial data and historical maps to quantify the spatially and temporally refined stocks of buildings and infrastructure and developed a novel indexing method to track the construction, demolition, and renovation for each building across various historical snapshots, with a case study of odense, denmark, from 1810 to 2018.We show that built environment stock in odense increased from 80 t/cap in 1810 to 279 t/cap in 2018.Their dynamics appear overall in line with urban development of odense over the past two centuries and well reflect the combined effects of industrialization, infrastructure development, socioeconomic characteristics, and policy interventions.Such spatiotemporally explicit stock mapping offers a physical and resource perspective for measuring urbanization and provides the public and government insight into urban spatial planning and related resource, waste, and climate strategies.

Journal: Environmental science & technology (2022)
Publication types: Journal Article;Research Support, Non-U.S. Gov't
The impact of adverse childhood experiences on adolescent health risk indicators in a community sample. Correction to Meeker et al. (2021).

Reports an error in "the impact of adverse childhood experiences on adolescent health risk indicators in a community sample" by elizabeth c.Meeker, briannon c.O'connor, lourah m.Kelly, debra d.Hodgeman, amy h.Scheel-jones and cassandra berbary (psychological trauma: theory, research, practice, and policy, 2021[mar], vol 13[3], 302-312).In the article, gender differences in 0, 1, and 2þ aces in table 1 were reversed and should have read as follows: 52.3% (n = 298) of youth with 0 aces were male, 51.2% (n = 205) of youth with 1 ace were male, and 41.2% (n = 230) of youth with 2þ aces were male; and 47.7% (n = 272) of youth with 0 aces were female, 48.8% (n = 195) of youth with 1 ace were female, and 58.8% (n = 328) of youth with 2þ aces were female.Further, in the first paragraph of the results, the sentence "the gender distribution for youth with a single ace were similar to the overall sample" should have read "the gender distribution for youth with a single ace were not significantly different." the online version of this article has been corrected.(the following abstract of the original article appeared in record 2021-14140-001.) objective: despite growing awareness of the high prevalence of adverse childhood experiences (aces) in community samples of adolescents, little work has examined the impact of aces on adolescence and well-being during this critical period of development.Much research has focused on retrospective reports of aces by adults and adult physical and mental health, finding that aces contribute to a range of diseases and mental health disorders in adulthood.This study examined differences in self-reported mental health, nonsuicidal self-injury, suicidality, violence, and substance use between adolescents without self-reported history of aces, youth with one self-reported ace, and youth with self-reported multiple (2 or more) aces.Method the sample included 1,532 adolescents who completed the youth risk behavior surveillance survey in their local high schools.By local consensus, this national survey was augmented with questions exploring prevalence of 11 commonly identified aces.Results after controlling for age, gender, and race, youth with multiple aces reported 3 to 15 times the odds of a range of negative health experiences.Conclusions findings indicate a serious burden of aces on adolescent social emotional well-being.This study did not include youth in out of school placements or who were not present the day the survey was given, and thus represent youth who may benefit from universal prevention and intervention programs.Universal screening of aces and health-related outcomes suggests that reporting multiple aces is strongly related to a wide range of mental health, violence, and substance use histories.(psyc info database record (c) 2022 apa, all rights reserved).

Journal: Psychological trauma : theory, research, practice and policy (2022)
Publication types: Journal Article
Ebselen and Analogues: Pharmacological Properties and Synthetic Strategies for Their Preparation.

Ebselen is the leader of selenorganic compounds, and starting from its identification as mimetic of the key antioxidant enzyme glutathione peroxidase, several papers have appeared in literature claiming its biological activities.It was the subject of several clinical trials and it is currently in clinical evaluation for the treatment of covid-19 patients.Given our interest in the synthesis and pharmacological evaluation of selenorganic derivatives with this review, we aimed to collect all the papers focused on the biological evaluation of ebselen and its close analogues, covering the timeline between 2016 and most of 2021.Our analysis evidences that, even if it lacks specificity when tested in vitro, being able to bind to every reactive cysteine, it proved to be always well tolerated in vivo, exerting no sign of toxicity whatever the administered doses.Besides, looking at the literature, we realized that no review article dealing with the synthetic approaches for the construction of the benzo[d][1,2]-selenazol-3(2h)-one scaffold is available; thus, a section of the present review article is completely devoted to this specific topic.

Journal: Molecules (Basel, Switzerland) (2021)
Publication types: Journal Article;Review
Evaluation of efficacy and safety of single-incision sling versus transobturator sling in women with stress incontinence and intrinsic sphincter deficiency.

Introduction and hypothesis urethral intrinsic sphincter deficiency (isd) is associated with severe urine leakage and a higher risk of sling failure.The aim of this study is to evaluate the efficacy and safety of single-incision slings (siss) versus transobturator slings (toss) in such patients.Methods patients who had stress incontinence and isd who underwent sis or tos procedures from 2010 to 2017 were retrospectively reviewed.The objective and subjective cure rates and surgical adverse events were compared between different slings.Objective cure was defined as no stress urine leakage with a comfortably full bladder.Subjective cure was determined by the patient's satisfaction.Incontinence-related symptom distress and quality of life were evaluated using the short forms of the urogenital distress inventory (udi-6) and incontinence impact questionnaire (iiq-7).Results among 111 patients, 37 underwent sis and 72 underwent tos with a median follow-up of 21 (range: 12-72) months and 24 (range: 14-84) months (p = 0.265).For both groups, the udi-6, iiq-7, and 1-h pad test all significantly improved after surgery (all p < 0.001).The objective and subjective cure rates were comparable after sis and tos procedures (objective: 76% vs.76%, p = 0.837; subjective: 78% vs.83%, p = 0.212).There were no significant differences in adverse events, except siss had a shorter surgery time (16.4 ± 9.3 vs.27.3 ± 12.4 min, p = 0.020) and lower postoperative visual analog scale pain score (1.3 ± 1.1 vs.3.9 ± 1.4, p < 0.001).Conclusion siss and toss had similar surgical results in women with stress incontinence and isd after at least 1 year of follow-up.However, siss had a shorter operation time and lower postoperative pain than toss.

Journal: International urogynecology journal (2022)
Publication types: Journal Article
Finite-time anti-saturation control for Euler-Lagrange systems with actuator failures.

This paper provides two bounded finite-time control strategies for the stabilization problem of euler-lagrange (el) systems exposed to actuator failures.By the combination of sliding mode technology and adaptive method, two control architectures have been constructed such that the system states will be forced towards the origin within finite time.The first controller is applicable in the case that exact information of the external disturbance and actuator faults are available.However, it still remains challenging for designers to obtain this sort of information in engineering practice.On account for this, adaptive laws are applied in the second controller to obtain estimations about the unknown parameters, thus ensuring desirable fault-tolerance ability and robustness for the el systems.By resorting to the properties of el systems and hyperbolic tangent functions, outputs of these two controllers will be proven to be bounded.Simulation examples are presented to manifest the validity of the developed algorithms.

Journal: ISA transactions (2022)
Publication types: Journal Article
Kisspeptin and attributes of infertile males and females: A cross-sectional study in a subset of Pakistani population.

Kisspeptin, a peptide hormone, plays a pivotal role in fertility and neuroendocrine regulation of hypothalamo-pituitary-gonadal axis.Increased kisspeptin and reproductive hormones are responsible for fertility in male and females.This study aimed to explore the role of kisspeptin on hypothalamo-pituitary-gonadal axis by comparing the levels of kisspeptin in fertile and infertile subjects and identifying single nucleotide polymorphisms (snps) of kiss1 gene in exon 2 and exon 3 of infertile male and female cohorts.A cross-sectional study was carried out on 80 males (44 infertile and 36 fertile) and 88 females (44 in each group).Significantly high levels of kisspeptin (kp), follicle-stimulating hormone (fsh), luteinizing hormone and testosterone were observed in fertile male and female subjects except low fsh levels in comparison with infertile female subjects.One polymorphism in exon 2 (e1225k [g/a 3673]) and three in exon 3 (p1945a [c/g 5833]; insertion of t at 6075; g2026g [c/g 6078]) in infertile group were detected, with low kp and hormonal levels.Male subjects had abnormal sperm parameters and unsuccessful attempt of intracytoplasmic sperm injection in females.Expression of snp in exon 2 and exon 3 of kiss1 could be responsible for alteration in release of reproductive hormones and gonadal functions, hence causing infertility.

Journal: Andrologia (2019)
Publication types: Journal Article
Click Chemistry of Melamine Dendrimers: Comparison of "Click-and-Grow" and "Grow-Then-Click" Strategies Using a Divergent Route to Diversity.

Dendrimers are attractive macromolecules for a broad range of applications owing to their well-defined shapes and dimensions, highly branched and globular architectures, and opportunities for exploiting multivalency.Triazine dendrimers in particular offer advantages such as ease of synthesis, stability, well-defined spherical structure, multivalency, potential to achieve acceptable drug loadings, and low polydispersity.In this study, the potential utility of alkyne-azide "click" cycloadditions of first-, second-, and third-generation triazine dendrimers containing three or six alkynyl groups with benzyl azide was examined using copper catalysts."click-and-grow" and "grow-then-click" strategies were employed.For the first- and second- generation dendrimers, the desired triazole derivatives were obtained in high yields and purified by simple reprecipitation without column chromatography; however, some difficulties were observed in the preparation of third-generation dendrimers.The desired reaction proceeded under microwave irradiation as well as with simple heating.This click chemistry can be utilized for various melamine dendrimers that are fabricated with other amine linkers.

Journal: Molecules (Basel, Switzerland) (2022)
Publication types: Journal Article