syedzayyan/paper_mill_benchmark huggingface dataset:
Effects of Camrelizumab Combined with First-Line Chemotherapy on Serum SCC, VEGF Levels, and Adverse Reactions in Patients with Advanced Squamous Cell Carcinoma of the Lung

To study the effects of camrelizumab accompanied by first-line chemotherapy on serum scc, vegf levels, and adverse reactions in people undergoing advanced lung squamous cell carcinoma.Methods.Data sources of the study subjects were 60 people suffering from advanced squamous cell carcinoma of the lung hospitalized from january 2018 to october 2019.They were assigned to two groups, including the control group and the observation group in a random manner, and each consisted of 30 patients.Those in the observation group received camrelizumab (shr-1210), and gemcitabine plus cisplatin (gp) chemotherapy were treated in the control group.Finally, according to the results, we compare the data of patients in both groups so as to find out the similarities and differences.Results.Among them, the effective efficiency of clinical treatment in the control group reached 36.67%, and that in the observation group reached 56.67%.Intuitively, it can be concluded that the control group showed lower results than the observed group.The observed group turned out to have higher periodic survival and progression free survival (pfs) of patients than the other group.During and after the cycle treatment, the data of scc and vegf were reduced to some extent, but the control group appeared to have a more evident reduction rate than the other group.Conclusion.Shr-1210 combined with chemotherapy has a considerable effect in practical application and has excellent clinical performance.

Journal: Computational Intelligence and Neuroscience (2022)
Publication types: Clinical Study;
Effects of Adding Ultrasound Biofeedback to Individualized Pelvic Floor Muscle Training on Extensibility of the Pelvic Floor Muscle and Anterior Pelvic Organ Prolapse in Postmenopausal Women

The aim of the study was to determine effects of adding transperineal ultrasound (tpus) biofeedback to individualized pelvic floor muscle training (pfmt) on extensibility of the pelvic floor muscle and anterior pelvic organ prolapse (pop) in postmenopausal women.A total of 77 patients with pop at stage i or stage ii were admitted to beijing shijitan hospital, china, from january 2017 to october 2018.They were randomly divided into a control group (cg) ( n = 37) or a study group (sg) ( n = 40).Both sg and cg received a 12‐week pfmt including health education, verbal instruction, and home training.However, the sg, but not the cg, received additional tpus biofeedback.Data of these patients were retrospectively reviewed.The distance from the lowest point of the bladder to the inferior‐posterior margin of the symphysis pubis (bsp) and the levator hiatus area (lha) were measured on maximal valsalva via tpus before and after the 12‐week pfmt.Correct pelvic floor muscle contraction (pfmc) rates before and after pfmt were compared between the two groups.The correct pfmc rate was higher in the sg than that in the cg (92.5% vs.73%; x 2 = 5.223, p = 0.022).The bsp was increased but the lha was reduced after the 12‐week pfmt in both groups compared to those before pfmt (all p &lt; 0.05).However, after the pfmt, the sg showed greater improvement than the cg for both bsp (0.77 ± 0.71 cm vs.0.11 ± 0.66 cm, p &lt; 0.05) and lha (20.69 ± 2.77 cm 2 vs.22.85 ± 3.98 cm 2 , p &lt; 0.05).Tpus might be an effective biofeedback tool for pfmt in clinical practice.Individualized pfmt with tpus biofeedback could significantly attenuate pop severity and strengthen the extensibility of pelvic floor muscle in postmenopausal women when they are under increased intraabdominal pressure.

Journal: Contrast Media & Molecular Imaging (2022)
Publication types: Research Article;
Effect of Roxadustat on Factors Associated with Renal Fibrosis and Efficacy

We investigated the effect of roxadustat on factors associated with renal fibrosis and efficacy.Methods.Sixty patients meeting the inclusion criteria between january 2021 and october 2021 were equally distributed into observation (roxadustat) group and control (erythropoietin) group.Then, the expression of serum hypoxia-inducible factor 1-alpha (hif-1α), transforming growth factor-β (tgf-β1), vascular endothelial growth factor (vegf), fibronectin (fn), and collagen iv (c-iv) was compared at different time points (baseline, 2-week follow-up, and 4-week follow-up).The improvement degree of hemoglobin (hb) and the change level of iron parameters and hepcidin were also compared between the two groups.Results.In the roxadustat group, the expression of hif-1α at 2 weeks was significantly higher than the baseline and approached the baseline value at 4 weeks.At 4 weeks, tgf-β1 and fn expression was significantly lower than baseline.In addition, the improvement of hb in the roxadustat group was significantly higher than that in the control group at 4 weeks, and the change of ferritin, transferrin, and hepcidin indexes from baseline was better than in the control group.Conclusion.After giving roxadustat, it can change the expression of hif-1α, tgf-β1, and fn.Its efficacy is superior to epo, which is worthy of clinical application.

Journal: Computational and Mathematical Methods in Medicine (2022)
Publication types: Clinical Study;
Effect and Safety of ALA-PDT Combined with 1550 nm Fractional Therapy Laser in Treating Rosacea

To explore the clinical effect and safety of 5-aminolevulinic acid photodynamic therapy (ala-pdt) combined with 1550 nm fractional laser therapy in the treatment of rosacea.Methods.114 patients with type i and type ii rosacea treated in our hospital from march 2018 to april 2020 were recruited.They were randomly assigned (1 : 1 : 1) to receive ala-pdt (photodynamic group), 1550 nm fractional laser (laser group), or ala-pdt and 1550 nm fractional laser therapy (combination group).Outcome measures included skin lesion scores, efficacy, and adverse reactions.Results.After treatment, patients in the three groups showed lower skin lesion scores than before treatment, and the combination group showed significantly lower results than the other groups ( p &lt; 0.05 ).There was no significant difference in the total efficacy among the three groups ( p &gt; 0.05 ), but the combination group outperformed the other groups in the comparison of the efficacy levels ( p &lt; 0.05 ).Edema with lupus erythematosus, pain, and burning sensation was found in some cases but disappeared within 2 to 4 days after symptomatic treatment without interference with subsequent treatment.No patients had pigmentation, hypopigmentation, scars, or other serious adverse reactions.Conclusion.In the treatment of rosacea, ala-pdt combined with a 1550 nm fractional laser can reduce redness and facilitate skin remodeling, with high efficacy and safety, so it is worthy of clinical promotion and application.

Journal: Evidence-Based Complementary and Alternative Medicine (2022)
Publication types: Clinical Study;
ECM-Mimicking Hydrogels Loaded with Bone Mesenchymal Stem Cell-Derived Exosomes for the Treatment of Cartilage Defects

It is well-established that treating articular cartilage injuries is clinically challenging since they lack blood arteries, nerves, and lymphoid tissue.Recent studies have revealed that bone marrow stem cell-derived exosomes (bmscs-exos) exert significant chondroprotective effects through paracrine secretions, and hydrogel-based materials can synergize the exosomes through sustained release.Therefore, this research aims to synthesize an ecm (extracellular matrix)-mimicking gelatin methacryloyl (gel ma) hydrogel modified by gelatin combined with bmscs-derived exosomes to repair cartilage damage.We first isolated and characterized exosomes from bmscs supernatant and then loaded the exosomes into gel ma hydrogel to investigate cartilage repair effects in in vitro and in vivo experiments.The outcomes showed that the gel ma hydrogel has good biocompatibility with a 3d (three-dimensional) porous structure, exhibiting good carrier characteristics for exosomes.Furthermore, bmscs-exos had a significant effect on promoting chondrocyte ecm production and chondrocyte proliferation, and the gel ma hydrogel could enhance this effect through a sustained-release effect.Similarly, in vivo experiments showed that gel ma-exos promoted cartilage regeneration in rat joint defects and the synthesis of related cartilage matrix proteins.

Journal: Evidence-Based Complementary and Alternative Medicine (2022)
Publication types: Research Article;
Development and Application of Sales System Software Based on Computer Network

In order to solve the problem that the automobile sales management becomes more and more complicated, this paper proposes a sales system software platform based on a computer network.The automobile sales management system based on the mvvm framework, with java as the development language and my sql as the database, is implemented by the progressive framework vue in the front end and developed by the spring boot framework in the back end.Starting with the design and implementation of the system, the technical framework, functional modules, and implementation processes used to develop the system are studied.The experimental results show that the function tests are normal, the response time of the system client is generally 1-2 seconds, the processing speed is fast, and the influence ability is good.The system improves the comprehensive management ability and promotes the rapid development of automobile industry.

Journal: Wireless Communications and Mobile Computing (2022)
Publication types: Research Article;
Design of Intelligent Diagnosis and Treatment System for Ophthalmic Diseases Based on Deep Neural Network Model

Artificial intelligence (ai) has developed rapidly in the field of ophthalmology.Fundus images have become a research hotspot because they are easy to obtain and rich in biological information.The application of fundus image analysis (ai) in background image analysis has been deepened and expanded.At present, a variety of ai studies have been carried out in the clinical screening, diagnosis, and prognosis of eye diseases, and the research results have been gradually applied to clinical practice.The application of ai in fundus image analysis will improve the situation of lack of medical resources and low diagnosis efficiency.In the future, the research of ai eye images should focus on the comprehensive intelligent diagnosis of various ophthalmic diseases and complex diseases.The focus is to integrate standardized and high‐quality data resources, improve algorithm efficiency, and formulate corresponding clinical research plans.

Journal: Contrast Media & Molecular Imaging (2022)
Publication types: Research Article;
Design of Epidemic Prevention Medical Special Clothing Based on Mathematical Model Analysis

Among the many diseases, the harm of infectious diseases is undoubtedly the first in terms of the scope of the disease and the threat to humans.In addition, most infectious diseases were regarded as terminal illnesses in the early stage of the outbreak.For example, smallpox and plague in history have even chosen to isolate patients and abandon them to prevent the spread of infectious diseases due to the lack of protection and treatment methods.Therefore, in the treatment of infectious diseases, epidemic prevention is very important.Based on this, this article discusses the research of special medical clothing design for epidemic prevention based on mathematical model analysis, hoping to provide strong help and support for epidemic prevention.First of all, this article understands the application status of mathematical models in the medical field and clothing design industry through literature research.Then, according to the functional requirements of antiepidemic medical special clothing in terms of protection from virus invasion and infection by other contact methods, this article established an antiepidemic clothing quality evaluation index system.Then, this article designs a simulation penetration test of pathogenic bacteria to test the protective function of the antiepidemic clothing and uses mathematical models to analyze the molecular structure and physical properties of the antiepidemic clothing materials.Finally, this article builds an analytic hierarchy model for the quality evaluation of epidemic prevention clothing based on the principle of analytic hierarchy process, analyzes the simulated experimental data and predicts the service life of the epidemic prevention clothing according to the performance degradation so that medical staff can replace it in time.The experimental results show that with the aid of mathematical model analysis, the quality of the epidemic prevention clothing is higher than the previous antiepidemic clothing design in terms of epidemic prevention performance, and in addition to the disposable epidemic prevention clothing, the multiple-use epidemic prevention clothing is not serious in the epidemic.Under these circumstances, it can maintain the antiepidemic performance for more than 2 months.

Journal: Mathematical Problems in Engineering (2021)
Publication types: Research Article;
Data Mining Technology for Agricultural Equipment Machinery and Information Network Data Resources

In order to realize the automation and intelligence of agricultural equipment mechanical state detection and improve the efficiency and accuracy of agricultural machinery equipment detection technology, this paper proposes an intelligent agricultural machinery equipment state detection method based on computer data mining.This method uses support vector machine to classify the equipment status and uses ant colony algorithm to solve the optimization problem.Its basic logic is to collect the status data of agricultural machinery equipment, extract the status detection characteristics of agricultural machinery equipment, and use computer data mining to establish an automatic state detection model of agricultural machinery equipment.The application results show that the correct rate of the state detection of agricultural machinery equipment is more than 95%, and the false detection rate of the state of agricultural machinery equipment is far lower than that of other current state detection methods of agricultural machinery equipment.Conclusion.This method can realize high-precision real-time detection of agricultural machinery equipment and has higher practical value.

Journal: Wireless Communications and Mobile Computing (2022)
Publication types: Research Article;
Data Analysis of Nursing Effects in Pediatric Gastroenterology Department under High Content Image Analysis Technology

Based on the nursing analysis of children aged 0∼3 in the department of gastroenterology, from the perspective of nursing methods and nutrition, bird’s nest nursing and high‐quality nursing methods were used to intervene children to help them improve their gastrointestinal conditions and sleep quality (su‐jin, 2021).Methods .A total of 2465 healthy children under 3 years were selected, with normal action and intelligence and accompanied by their parents.Among them, there were 635 children in the observation group (o group) and 355 children in the reference group (r group) in the bird’s nest nursing group, 572 children in the o group and 603 children in the r group in the other high‐quality nursing group.The observation group received routine nursing, while the control group received nest nursing and quality nursing.The height growth rate, weight growth rate, brain weight growth rate, blood cell routine, and serum biochemical examination results of infants aged 6 months and 3 years in the o group, image analysis technology is used to analyze and discuss the gastrointestinal imaging examination of children, so as to conduct more detailed and accurate research.Results .Through the analysis and comparison of the physiological index data of 6‐month‐old and 3‐year‐old infants in the observation group and the reference group, and the satisfaction of parents, it was found that the children’s physiological indexes, gastrointestinal digestion, weight gain, and brain weight gain rate through bird’s nest care and high‐quality care were slightly better than those in the observation group, and the parents’ satisfaction was also slightly higher.Conclusion .Wei et al.(2020).By creating a comfortable environment and simulating the children’s growth environment under the mother’s care, it is found that the bird’s nest care and high‐quality care programs can calm children’s emotions, increase children’s appetite and digestion, so as to promote children’s gastrointestinal digestion and achieve the goal of healthy growth (wei et al, 2020).Finally, the conclusion is drawn that starting from the needs of children, scientific and correct gastrointestinal care and dietary nutrition should be used to promote the healthy growth of children.

Journal: Contrast Media & Molecular Imaging (2022)
Publication types: Clinical Study;
Dancer Tracking Algorithm in Ethnic Areas Based on Multifeature Fusion Neural Network

Due to the complex posture changes in dance movements, accurate detection and tracking of human targets are carried out in order to improve the guidance ability of dancers in ethnic areas.A multifeature fusion-based tracking algorithm for dancers in ethnic areas is proposed.The edge contour model of video images of dancers in ethnic areas is detected, and the video tracking scanning imaging model of dancers in ethnic areas is constructed.The video images of dancers in ethnic areas are enhanced based on the initial contour distribution, and a visual perception model of dancers tracking images in ethnic areas is established.To improve the algorithm’s estimation of complex poses and finally complete the dance movement recognition, a feature pyramid network is used to extract the features of dance movements, and then, a multifeature fusion module is used to fuse multiple features.The tracking algorithm proposed in this paper has higher robustness than other algorithms and effectively reduces the error samples generated during the tracking process, thus improving the accuracy of long-term tracking.

Journal: Wireless Communications and Mobile Computing (2022)
Publication types: Research Article;
Correlation of Gastric Cancer Cells with Seasonal Changes under Microscope

Today, with the development of medical technology, stomach cancer remains to be one of the most common causes of death associated with cancer.Studies show that the incidence of stomach cancer varies in different areas but is more common in china.Most patients were diagnosed late with local or remote metastasis.The data show that the survival rate within five years is less than 10%.Therefore, it is very important to study the gastric cancer cells systematically, explore the factors that lead to the change of the number of gastric cancer cells, and put forward practical suggestions for the prevention and control of the disease.This paper analyzes the disease-related information of several patients with gastric cancer in a hospital, discusses the growth of gastric cancer cells and season-related factors, and analyzes the single factor of gastric cancer patients and season-related possible factors.In this paper, we choose to observe gastric cancer cells in different seasons under the microscopic environment to further explore the influence of seasons on gastric cancer cells.The results showed that gastric cancer cells grew faster under microscope in spring and summer.We found that the incidence rate of gastric cancer in spring and summer was higher than that in autumn and winter.Diabetic patients and diabetes history are important risk factors of gastric cancer in spring and summer.Therefore, we advocate healthy lifestyle, pay attention to their poor performance in life, and actively help them to correct, which is of positive significance for the prevention and control of gastric cancer.

Journal: Mathematical Problems in Engineering (2021)
Publication types: Research Article;
Research on Site Safety Management by BIM Technology Based on Fuzzy Intuition Set

The application of building information modeling technology on a smart site can take advantage of the coordination, visualization, and simulation capabilities of this technology, allowing the engineering design and construction of the site to be based on a bim model.In the construction of any engineering project, an accurate bim model can be created using engineering information and data gathered at an early stage.Even though the “smart site” management system and bim technology have some positive effect on safety production management, there is still room for improvement.This paper introduces the characteristics of safety and security management through the analysis of bim big data and then selects evaluation indices.Using administrator experience and fuzzy inference tools, inference rules are then established and inference models are designed.Lastly, example validation and comparative analysis verify the method’s rationality and efficacy, providing a basis for the administrator’s deployment decision for the safety production command.Experiments show that the method proposed in this paper can be better applied to site safety management.

Journal: Security and Communication Networks (2022)
Publication types: Research Article;
Progress Planning Method of Strength Quality Training of Volleyball Players Based on Data Mining

In order to better realize the training effect of volleyball players’ strength quality and accelerate the training progress of volleyball players’ strength quality, this paper puts forward the planning method of volleyball players’ strength quality training progress based on data mining, constructs the training management system of volleyball players’ strength quality by using data mining algorithm, and excavates the evaluation indexes of volleyball players’ strength quality training quality, finally, through experiments, it is confirmed that the volleyball player strength quality training schedule planning method based on data mining has high practicability in the process of practical application and fully meets the research requirements.

Journal: Mathematical Problems in Engineering (2022)
Publication types: Research Article;