syedzayyan/paper_mill_benchmark huggingface dataset:
Changes of pollen viability after preservation of Paeonia lactiflora in different provenances.

Pollen contains all the haploid genetic information of species and is of great significance to preserve germplasm resources safely and effectively.The acquisition of high quality materials is a very important step in germplasm preservation.This study compared the viability and physiological condition of paeonia lactiflora pollen from several provenances after preservation, to explore the effect of provenance difference on pollen viability and physiological responses after preservation.The results showed that: the pollen viability of two cultivars were significantly different in provenances after preserved at -20 °c or liquid nitrogen (ln) for 3 months, the pollen viability of 'fen yu nu' showed lanzhou > beijing > luoyang > heze, while the pollen viability of 'zi feng chao yang' showed luoyang > beijing > heze.Similarly, the oxidative stress levels of the paeonia lactiflora pollen after preservation with ln or -20 °c were also significantly different among the provenances, and there was a relationship between the viability and the oxidative stress levels produced by the provenances differences.Reactive oxygen species (ros) content, malondialdehyde (mda) content, superoxide dismutase (sod) activity and glutamate reductase (gr) activity in pollen from different provenances were contrary to the changes of viability; while catalase (cat), ascorbic acid peroxidase (apx), ascorbic acid (as a) and glutathione (gsh) were consistent with the changes of viability.The results indicated that the responses of antioxidant systems of two cultivars pollen to preservation with ln or -20 °c were different in provenances, and this difference was one of the reasons for the different viability of pollen after preservation with ln or -20 °c.

Journal: Cryobiology (2022)
Publication types: Journal Article;Research Support, Non-U.S. Gov't
Tree species as a biomonitor of metal pollution in arid Mediterranean environments: case for arid southern Tunisia.

We investigated the accumulation of zn, cu, pb, and cd in the soil and the leaves and bark of five common tree species (eucalyptus occidentalis endl., acacia salicina lindl., cupressus sempervirens l., casuarina equisetifolia l., and tamarix aphylla (l.) karst.) in the city of gabès tunisia to elucidate their bioaccumulation potential and determine their usefulness as biomonitors of metallic pollution in arid urban areas.Our results indicated that the bark had higher mean concentrations of pb and cd than leaves.In contrast, the leaves had higher mean concentrations of zn and cu than bark.No hyperaccumulation was detected for any of the analyzed metals in any of the studied species.E.Occidentalis and t.Aphylla had the highest mean concentrations of the investigated metals in leaves and bark.Based on the calculated metal accumulation index (mai) values, these two species accumulated more metals than other studied tree species.Likewise, the concentrations of zn, cu, pb, and cd in soil had significant positive correlations with that in leaves and bark.Accordingly, e.Occidentalis could be used for biomonitoring in arid areas subjected to industrial and traffic pollution.T.Aphylla would be a good alternative when native species are a priority.

Journal: Environmental science and pollution research international (2021)
Publication types: Journal Article
Advanced Practice Nursing Roles: A Comparison Between Mexico and the United Kingdom.

The covid-19 pandemic has placed nursing at the forefront of public attention across the globe and has highlighted the critical role of nursing in healthcare service provision.Advanced practice nursing has been recognized for more than 50 years, but the rate of its growth and development varies significantly across the world.One of the key aims of the better health programme mexico, which commenced in 2019, was to develop advanced practice nursing in mexico.The programme was based on the united kingdom model, where advanced practice nursing has been in place-though not subject to statutory regulation-for more than 40 years.The aim of this article is to compare the frameworks that underpin advanced practice nursing in the united kingdom and in mexico.In the present article, current practice in both countries was researched, and the structure, systems, and processes relating to nursing regulation and the frameworks to support advanced practice nursing were examined.A gap analysis report undertaken as part of the better health programme identified challenges in developing advanced practice nursing in mexico and the united kingdom and highlighted the need for stakeholders to agree on an approach toward a rigorous regulatory framework in both settings.In summary, this article highlights the issues facing nurses and regulators in both countries in terms of advanced practice nursing and identifies strategies that can be used to strengthen the advanced practice nurse role.

Journal: Journal of nursing regulation (2022)
Publication types: Journal Article
The safety and effectiveness of elective laparoscopic surgery for benign ovarian cysts during pregnancy-Comparison with emergency surgery.

Relatively small benign ovarian cysts are conservatively managed in early pregnancy.However, emergency surgery is required should acute abdomen occur.Our study aimed to examine and compare the outcomes of benign ovarian cysts treated with elective laparoscopic surgery or emergency surgery during pregnancy.Methods from 2004 to 2017, we treated 135 pregnant patients (110 elective and 25 emergencies) with benign ovarian cysts at our tertiary perinatal center and compared their surgical and perinatal outcomes.Results there was no significant difference in cyst diameter (7.6 ± 2.5 vs.6.8 ± 2.1 cm), but cysts <6 cm were significantly more common in emergency (36%) than in elective (15%) cases.Mature teratomas were significantly more common in elective cases (89% vs.52%) but corpus luteum cysts were more common in emergency cases (0% vs.32%).The rates of laparoscopic surgery (98.2% vs.52.0%) and ovarian conservation (99.1% vs.80.0%) were significantly higher, and post-surgical hospitalization (4.6 ± 1.3 vs.9.8 ± 10.5 days) was significantly shorter in elective than in emergency cases.There was no significant difference in the gestational age for delivery (38.9 ± 1.9 vs.38.4 ± 2.7 weeks), preterm birth rate (12% vs.20%), or birth weight (2939 ± 469 vs.3019 ± 510 g).Conclusions we cannot state that an emergency surgery during pregnancy is rarely required for small benign ovarian cysts.However, the surgical outcomes were significantly better for elective than for emergency surgery, with no difference in perinatal outcomes.If a benign ovarian cyst is found early in pregnancy, elective laparoscopic surgery may be considered with adequate informed consent.

Journal: The journal of obstetrics and gynaecology research (2022)
Publication types: Journal Article
The impulsiveness level influences the salivary cortisol response and social stress sensitivity in suicidal patients.

Introduction suicide attempters (sa) are more vulnerable to social stress and show disturbed cortisol response in stressful conditions compared with psychiatric and healthy controls.Recent data suggest that this dysregulation might be related to impulsivity traits.However, little is known about the emotional consequences of social stress in sa exposed to stress.Objectives the aim of our study was to evaluate the cortisol and emotional responses to social stress in patients with depression with and without suicide attempt, by taking into account impulsivity traits and depression severity.Methods 67 adult women (41 sa and 26 affective controls (ac,i.e.Without suicide attempt history)) with lifetime history of major depressive episode were included.Patients performed the trier social stress test (tsst), a well-validated social stress task.Patients provided seven saliva samples, to measure the cortisol response, and filled in questionnaires to assess psychological pain, positive and negative mood, and anxiety at different time points (from 10 min before to 120 min after the tsst).Moderated regression models were used including suicide attempt history, depression severity, and impulsivity as independent variables and their interactions.Results in patients with low depression and high impulsivity, salivary cortisol response during the tsst was higher in sa than in ac (p < .001).Psychological pain, negative mood, and anxiety were increased in all patients just after the tsst, followed by a decrease at 120 min.Positive mood recovery was slower in sa, and in patients with high impulsivity and low depression level (p < .001).Conclusions impulsivity traits have an important role in suicidal vulnerability in stress conditions.Impulsivity traits might help to differentiate patients at risk of suicide who are highly sensitive to stress when depression level is low.Higher impulsiveness may increase the sensitivity to emotional distress that translates into inadequate physiological responses.

Journal: Journal of psychiatric research (2022)
Publication types: Journal Article;Research Support, Non-U.S. Gov't
miR-26a attenuates colitis and colitis-associated cancer by targeting the multiple intestinal inflammatory pathways.

Patients with inflammatory bowel disease are at increased risk for colitis-associated colorectal cancer (cac).Therefore, controlling intestinal inflammation is a key therapeutic strategy for cac.Micro rnas (mi rnas or mi rs) are a family of small noncoding rnas that have the capacity to regulate fundamental biological processes.To date, a number of mi rnas have been identified as critical regulators of inflammation.However, the specific role of mi r-26a in colonic inflammation and colitis-associated carcinogenesis is still elusive.Here, we generated mice with mi r-26a myeloid-cell-specific overexpression to show that mi r-26a suppressed the intestinal inflammatory response in macrophages by decreasing nuclear factor κb (nf-κb)/stat3 activation and interleukin 6 (il-6) production.At the molecular level, a number of nf-κb regulators, including tlr3, pten, and pkcδ, were identified as potential targets of mi r-26a.Our results thus identify a novel mi rna-mediated mechanism that suppresses carcinogenic inflammation in the colon.

Journal: Molecular therapy. Nucleic acids (2021)
Publication types: Journal Article
From Bilateral Periorbital Necrotic Wound to Fungal Brain Abscess: A Complicated Case of COVID-19-Associated Mucormycosis.

Covid-19-associated mucormycosis (cam) is categorized as rhinocerebral-orbital (rcom), pulmonary, gastrointestinal, cutaneous, and disseminated mucormycosis.An alarming surge in morbidity and mortality attributed to mucormycosis concurrent with coronavirus disease 2019 (covid-19) has emerged as a cause for concern during the current outbreak of covid-19.The global incidence of cam has been attributed to environmental, host, and iatrogenic factors.Further,mucoralesinteracting with epithelial cells followed by endothelium invasion are pivotal in developing mucormycosis in patients with covid-19.In essence, cam is an emerging condition that requires increased vigilance in all covid-19 patients, including those who have recovered.In this case report, we describe a rare case of cam in a 33-year-old immunocompetent man who developed bilateral periocular pain and a small area of cutaneous necrosis in both medial canthi associated with impaired vision, which progressed into a fungal brain abscess formation in the post-covid period.Furthermore, this case aims to illustrate the potential underlying risk factors of cam other than known risk factors, especially in immunocompetent individuals.

Journal: Case reports in infectious diseases (2022)
Publication types: Case Reports;Journal Article
Interpersonal cognitive distortions and family role performances in spouses during COVID-19 pandemic process in Turkey.

This study aimed to examine the relationship between interpersonal cognitive distortions and family role performances in spouses during the pandemic process.Design and methods this cross-sectional study was conducted on 402 married individuals.Findings the total score of interpersonal cognitive distortions and task performance scores were higher in males.The individuals who go to the workplace during the coronavirus disease 2019 (covid-19) process have higher unrealistic relationship expectancy score and total score of interpersonal cognitive distortion.Interpersonal cognitive distortions were determined to explain 5% of task and relationship performance in family role performance.Practice implications it was determined that the relationships in the spouses were associated with cognitive distortions and family role performance.Interpersonal cognitive distortions in spouses were found to affect role performance in the family.

Journal: Perspectives in psychiatric care (2022)
Publication types: Journal Article
2022 ONS Congress® Podium Abstracts.

Each abstract has been indexed according to first author.Abstracts appear as they were submitted and have not undergone editing or the oncology nursing forum's review process.Only abstracts that will be presented appear here.For ons congress® scheduling information, visit congress.ons.org.Data published in abstracts presented at the 47th annual ons congress are embargoed until the conclusion of the presentation.Coverage and/or distribution of an abstract, poster, or any of its supplemental material to or by the news media, any commercial entity, or individuals, including the authors of said abstract, is strictly prohibited until the embargo is lifted.Promotion of general topics and speakers is encouraged within these guidelines.

Journal: Oncology nursing forum (2022)
Publication types: Journal Article
Antisymmetric Spin Exchange in a μ-1,2-Peroxodicopper(II) Complex with an Orthogonal Cu-O-O-Cu Arrangement andS= 1 Spin Ground State Characterized by THz-EPR.

A unique type of cu2/o2adduct with orthogonal (close to 90°) cu-o-o-cu arrangement has been proposed for initial stages of o2binding at biological type iii dicopper sites, and targeted ligand design has now allowed us to emulate such an adduct in a pyrazolate-based μ-η1:η1-peroxodicopper(ii) complex (2) with cu-o-o-cu torsion φ of 87°, coined⊥pintermediate.Full characterization of2, including x-ray diffraction (d o-o= 1.452 å) and raman spectroscopy (ν̃o-o= 807 cm-1), completes a series of closely related cu2/o2intermediates featuring μ-η1:η1-peroxodicopper(ii) cores with φ ranging from 55° (a,cis-peroxo cp; brinkmeier a.et al., j.Am.Chem.Soc.2021, 143, 10361) via 87° (2,⊥ptype) up to 104° (b, approachingtrans-peroxo tp; kindermann n.et al., angew.Chem., int.Ed.2015, 54, 1738).Squid magnetometry revealed ferromagnetic interaction of the cu iiions and a triplet (st= 1) ground state in2.Frequency-domain thz-epr has been employed to quantitatively investigate the spin systems of2and b.Magnetic transitions within the triplet ground states confirmed their substantial zero-field splittings (zfs) suggested by magnetometry.Formally forbidden triplet-to-singlet transitions at 56 (2) and 157 cm-1(b), which are in agreement with the exchange coupling strengths jisoinferred from squid data, are reported for the first time for coupled dicopper(ii) complexes.Rigorous analysis by spin-hamiltonian-based simulations attributed the corresponding nonzero transition probabilities and the zfs to substantial antisymmetric (dzyaloshinskii-moriya) exchangedand provided robust values and orientations for thed,j, andgtensors.These interactions can be correlated with the cu-o-o-cu geometries, revealing a linear increase of jisowith the cu-o-o-cu torsion and a strong linear decrease with the cu-o-o angle.Relevance of the⊥pintermediate for o2activation at type iii dicopper sites and a potential role of antisymmetric exchange in the concomitant intersystem crossing are proposed.

Journal: JACS Au (2022)
Publication types: Journal Article
Transition in successors' behavior and mindset while managing long-lived small and medium-sized manufacturing enterprises: a qualitative study.

There have been many studies conducted on succession, which can be considered as the most important issue in family businesses.However, most of these previous studies have focused only on the early stage of succession, uncovering the role of the predecessor and the successor.Only a few studies have made efforts to examine the total lifecycle of succession.The purpose of this study is to explore the process of the transition in successors' behavior and mindset while managing long-lived small and medium-sized manufacturing enterprises throughout the lifecycle of succession.methods:semi-structured interviews were conducted with six successors of small and medium-sized manufacturing companies who are more than half a century old.Their answers were analyzed using the modified-gta method to construct a hypothetical model.results:in total, 46 concepts, four categories, 17 subcategories, and one core category were generated.An analysis result diagram using all concepts and categories was formed.From the observation of this diagram, the successors gained confidence in management through the dilemma between autonomy and constraint in the early stage of succession, which was found in previous research.Following the initial stage, the successors responded to the crisis caused by market constraints and created autonomous strategies in their businesses.conclusions:by experiencing repetitive crises, the successors tend to acquire new perspectives toward the naturally occurring crises.This change of premise by the successors is considered as the process of double-loop learning.Relationships inside and outside the company influence the generation of this viewpoint.From a long-term perspective, a sense of unity with employees, stable employment, and the pursuit of enjoyment constitute the successors' own values in this model.

Journal: F1000Research (2021)
Publication types: Journal Article
A comparative study of marine litter on the seafloor of coastal areas in the Eastern Mediterranean and Black Seas.

In the present work, abundance, spatial distribution and qualitative composition, of benthic marine litter, were investigated in five study areas from the eastern mediterranean and black seas (saronikos, patras and echinades gulfs; limassol gulf; constanta bay).Surveys were performed using the monitoring protocol proposed by the technical group for marine litter.Densities ranged from 24items/km(2) to 1211items/km(2), with the saronikos gulf being the most affected area.Plastics were predominant in all study areas ranging from 45.2% to 95%.Metals and glass/ceramics reached maximum values of 21.9% and of 22.4%.The size distribution of litter items showed that ⩾50% fall into medium size categories (10×10cm, 20×20cm) along with an elevated percentage of small-sized (<5×5cm) plastic litter items.The comparative analysis of the data highlighted the dependence of the marine litter problem on many local factors (human sources and oceanographic conditions) and the urgent need for specific actions.

Journal: Marine pollution bulletin (2014)
Publication types: Comparative Study;Journal Article;Research Support, Non-U.S. Gov't
Endoplasmic Reticulum Stress: A New Research Direction for Polycystic Ovary Syndrome?

Polycystic ovary syndrome (pcos) is one of the most common gynecological endocrine disorders, with sporadic ovulation, excessive androgens, and polycystic ovarian changes as the main clinical manifestations.Due to the high heterogeneity of its clinical manifestations, the discussion on its pathogenesis has not been unified.Current research has found that genetic factors, hyperandrogenism, chronic inflammation and oxidative stress, insulin resistance, and obesity are strongly associated with pcos.Recently, when studying the specific mechanisms of the abovementioned factors in pcos, the biological response process of endoplasmic reticulum stress (ers) has gradually come to researchers' attention, and several studies have confirmed the involvement of ers in the pathogenesis of pcos and the improvement of a series of pathological manifestations of pcos after the application of ers inhibitors, which may be a new entry point for the treatment of pcos.In this article, we review the relationship between ers and various pathogenic factors of pcos.

Journal: DNA and cell biology (2022)
Publication types: Journal Article;Review
The Emerging Role of EVA1A in Different Types of Cancers.

Eva-1 homolog a (eva1a), also known as transmembrane protein 166 (tmem166) and regulator of programmed cell death, is an endoplasmic reticulum associated protein, which can play an important role in many diseases, including a variety of cancers, by regulating autophagy/apoptosis.However, the related mechanism, especially the role of eva1a in cancers, has not been fully understood.In this review, we summarize the recent studies on the role of eva1a in different types of cancers, including breast cancer, papillary thyroid cancer, non-small cell lung cancer, hepatocellular carcinoma, glioblastoma and pancreatic cancer, and analyze the relevant mechanisms to provide a theoretical basis for future related research.

Journal: International journal of molecular sciences (2022)
Publication types: Journal Article;Review
Feasibility of the single-incision subxiphoid approach for video-assisted thoracoscopic surgery in dogs.

S to report early results of uniportal video-assisted thoracoscopic surgery in dogs using a single-incision subxiphoid approach.Materials and methods retrospective study of 10 client-owned dogs with: pyothorax (n=5), pericardial effusion (n=2), bilateral pneumothorax (n=1), retained surgical swab (n=1), cranial mediastinal mass (n=1).With the dog in dorsal recumbency a 3-4 cm incision was made over the xiphoid process.After resection of the xiphoid process, a tunnel was created towards the pleura and open access maintained with an alexistm wound retractor.The pleural cavity was explored with a 10 mm 30° or 5 mm 0° telescope and straight laparoscopic instruments.Results median surgical time was 75 minutes.The sisa technique was performed successfully in five of 10 cases and allowed easy and adequate inspection of the intra-thoracic structures.One case was converted to lateral thoracotomy after laceration of the vena cava and one converted to median sternotomy because of adhesions.An additional port was placed in three cases to facilitate triangulation and surgical manipulation.No other intra-operative complications were encountered.Clinical significance in this initial report of uniportal thoracic approach in dogs, this technique allowed excellent access and treatment of mediastinal structures.Further cases are required to assess its suitability for pulmonary surgery.

Journal: The Journal of small animal practice (2020)
Publication types: Journal Article