syedzayyan/paper_mill_benchmark huggingface dataset:
Mutational Screening of Skeletal Genes in 14 Chinese Children with Osteogenesis Imperfecta Using Targeted Sequencing

As a heterogeneous hereditary connective tissue disorder, osteogenesis imperfecta (oi) is clinically characterized by increased fracture susceptibility.Analysis of genetic pathogenic variants in patients with oi provides a basis for genetic counseling and prenatal diagnosis.Methods.In this study, 14 diagnosed oi patients from sporadic chinese families were enrolled to be screened for potential mutations from these patients by next-generation sequencing technology.Results.34 different variants were identified.18 variants were from 4 oi-related genes including col1a1, col1a2, p3h1, and wnt1, and 10 variants are novel.Most oi patients (11 out of 14, 78%) harbor variants in type i collagen genes.Conclusions.Our results support previously established estimates of the distribution and prevalence of oi mutations and highlight both phenotype and genetic heterogeneity among and within families.We report several novel variants of oi, which expands the clinical spectrum of oi.In summary, our data provides disease-causing genes information for genetic counseling towards oi patients and families and also provides a reference for clinicians in the diagnosis of oi, also in prenatal diagnosis of this disease.

Journal: Journal of Immunology Research (2022)
Publication types: Research Article;
Study on Resource Sharing Strategy of e-Commerce Innovation and Entrepreneurship Education Based on Cloud Computing

As a popular education major at present, e-commerce and innovation and entrepreneurship education are combined with research that has important strategic significance for talents.In the process of the coordinated development of the two, the sharing of educational resources is the core issue.For this reason, an e-commerce professional innovation and entrepreneurship education resource sharing platform has been constructed.The platform is divided into three hierarchical structures of resource layer, middle layer, and application layer, and detailed analysis is performed on the key modules in the construction of the educational resource sharing platform, including user login module, educational resource management module, system management module, and database design module; based on modular design, after logging in to the system, users can independently publish educational information and can also browse and retrieve shared resources.Experimental results show that the platform has a good operating effect, strong load capacity, rapid response of the system, and high safety performance, with a maximum safety of 97%.

Journal: Scientific Programming (2021)
Publication types: Research Article;
Research on the Application of Environmental Art Design Based on the Combination of VR and Panoramic Video Technology

The panoramic video technology is introduced to collect multiangle data of design objects, draw a 3d spatial model with the collected data, solve the first-order differential equation for the 3d spatial model, obtain the spatial positioning extremes of the object scales, and realize the alignment and fusion of panoramic video images according to the positioning extremes above and below the scale space.Then, the panoramic video is generated and displayed by computer processing so that the tourist can watch the scene with virtual information added to the panoramic video by wearing the display device elsewhere.It solves the technical difficulties of the high complexity of the algorithm in the system of panoramic video stitching and the existence of stitching cracks and the “ghost” phenomenon in the stitched video, as well as the technical difficulties that the 3d registration is easily affected by the time-consuming environment and target tracking detection algorithm.The simulation results show that the panoramic video stitching method performs well in real time and effectively suppresses stitching cracks and the “ghost” phenomenon, and the augmented reality 3d registration method performs well for the local enhancement of the panoramic video.

Journal: Scientific Programming (2021)
Publication types: Research Article;
The Connotation and Realization Path of Ecological Civilization Education in Chinese Universities under the Background of Mobile Internet

The report of the 18th national congress of the communist party of china creatively clarified the general pattern of socialist construction as “five-in-one,” namely, the construction of economy, politics, culture, society, and ecological civilization and pointed out that the construction of ecological civilization should lead and integrate into socialism.This marks that china has entered a new era of ecological civilization and started the great historical journey of building a beautiful china.Ecological civilization education in colleges and universities is an important content and foundation of ecological civilization construction, which can provide sufficient human resources and intellectual preparation for ecological civilization construction, promote the popularization of ecological civilization concept in society, and promote the ecological transformation of economic and social development.Therefore, the education of ecological civilization in colleges and universities is not only the meaning of the integration of ecological civilization into higher education but also an initiative to implement the national strategy, and it is also a realistic demand for realizing the fundamental task of morality and cultivation of people in higher education.This research uses mobile internet technology to study the path of ecological civilization education in chinese colleges and universities mainly using the questionnaire survey method, on the basis of multiple stratified sampling, with the help of the revised chinese new environmental paradigm scale (chinese new environmental paradigm scale) to collect data.

Journal: Mobile Information Systems (2022)
Publication types: Research Article;
Realization of an Intelligent Image Processing Technology for the Analysis of Chinese Painting Color Education

An intelligent information recognition technology based on picture image processing was proposed to further improve the application effect of intelligent image technology in the color teaching of painting major and improve the level of chinese painting color teaching with the aid of intelligent image processing technology.Special image recognition technology was used to effectively identify the color of chinese paintings based on traditional teaching methods.Matlab software for simulation processing of chinese painting was also utilized through the fuzzy set theory test sample image recognition.The results show that the method is based on feature vector extraction and orthogonal basis transformation histogram.The former takes 0.072288 seconds in image recognition time, while the latter takes 0.134939 seconds, which is nearly double the former time.Therefore, the software and image processing technology mentioned in the article can further improve the effect and time of image color recognition.

Journal: Mobile Information Systems (2022)
Publication types: Research Article;
Exploration of Agricultural Economic Management Methods under Internet + Mode

In order to solve the problems that the production management of agricultural greenhouses consumes large human resources, low management efficiency, and the limitations of environmental monitoring, a visualized smart agriculture based on zig bee and wi fi dual-protocol fusion wireless sensor networks (wsns) technology is proposed.A management system is proposed.The system takes stm32 as the main control core and builds a visual cloud computing platform based on the esp8266wi fi module.The environmental parameters of the greenhouse are sent to the zig bee terminal device through the serial port, and the user can remotely monitor the environmental parameters of the greenhouse in real time through the computer and mobile client, and control the working status of each actuator.The test results show that: (transmission control protocol/internet protocol, tcp/ip) communication is not abnormal; under the control of the visual management system, when the system sends out control commands, the response time of each output terminal is basically between 1 and 2 s.The response of the output control unit has high sensitivity.Affected by the network delay, the fourth group of test data is larger, and in the case of network delay, the response sensitivity of each output terminal of the system decreases accordingly.Conclusion.The system has high accuracy of data collection, strong work reliability, can realize precise remote control, and has low cost, high stability, easy operation, and has certain promotion value.

Journal: Mobile Information Systems (2022)
Publication types: Research Article;
Emergency Management System for Coal Mine Safety Based on IoT Technology

The internet of things (io t) has brought technological innovation to various industries, and it has also brought great impact to coal industry.It is important to study the safety supervision system of coal in the io t mode to improve effectiveness of safety supervision and make suggestions to improve safety production in coal.In this paper, based on analysis of influence factors and emergency supervision system in the io t mode, system dynamics modeling theory and method are used to construct a system dynamics model of influence factors and emergency supervision in the io t mode.The validity and reliability of the model are verified by the system dynamics software to reach more than 98.6%, and the support for the development of coal internet of things is appropriately increased to support the development of coal internet of things, ensure the healthy and long-term development of coal internet of things, improve the level of supervision, and ensure the safe production of coal

Journal: Mobile Information Systems (2022)
Publication types: Research Article;
Economic Supply Chain Management System of Farm Products Industry Based on the Belt and Road under the Background of Big Data

Under the strategic background of “one belt, one road,” the future farm products industry will also become part of the country’s core competitiveness.Promoting the transformation of enterprises in the supply chain is conducive to cultivating the country's core competitiveness and creating good output conditions for china’s manufacturing industry.Under the national strategy of “one belt, one road,” the agricultural product industry is facing new development opportunities.This paper analyzes the background, significance, and existing basic problems of the “one belt, one road.” starting from the economic development of the national agricultural product industry, it uses the cluster analysis algorithm to analyze the current overall economic situation of the agricultural product industry and points out the current problems in the industry.The product industry is facing greater pressure for transformation and upgrading.Finally, combined with the strategic background of “one belt one road,” from the perspectives of society, government, and enterprises, analyzed its supply chain process, extracted relevant problems, and put forward relevant countermeasures and suggestions from the perspective of intrachain, extrachain, and their interactive integration.

Journal: Mobile Information Systems (2022)
Publication types: Research Article;
Artistic Expression in Visual Communication Design in Multimedia Background

The application of multimedia technology has realized the transformation of people’s production and lifestyle, and also promoted the improvement of people’s aesthetic ability.At present, the application of multimedia in the field of art is increasing, and traditional artistic expression has been unable to satisfy the people’s appreciation of beauty.Using high-efficiency production and extensive communication technology, this paper aims to study the research on artistic expressions in visual communication design in the multimedia environment, which is helpful to analyze the role and influence of current artistic elements on visual communication design.It draws on the principles and laws of visual communication design to analyze and evaluate image processing techniques and to realize the ecology of visual communication design.The results show that the highest error rate for low iterations is only 0.014.In the comparison of the method in this paper with other methods, it is found that the method in this paper has the shortest iteration time and the least number of iterations.Among them, the iteration time is 2.945 s, the number of iterations is 10, and the error rate is 0.0016.It can be seen from the identified pictures that the iteration time of the method in this paper is 2.647 s, and the number of iterations is only 10.Therefore, it is crucial to analyze image-based artistic expressions.

Journal: Mobile Information Systems (2022)
Publication types: Research Article;
Application of Computer 3D Modeling Technology in Modern Garden Ecological Landscape Simulation Design

The use of digital technology (dt) to systematically plan and design ul can further progress the urban environment.Digital landscape as a new vector of landscape planning and design is oriented to dt.The promotion of dt improves the science and accuracy of ul planning and designs and promotes sustainable development.A city in the south was used as an example to reconstruct and restore the historical appearance of the city from four aspects: virtual process, reconstruction method, digital construction, and virtual interactive roaming technology, and a new way was found for the application of digital landscape in urban construction.The scientific and creative nature of ul is becoming increasingly prominent as the digital era progresses, and ul is no longer just an exterior manifestation of artistic configuration but also a humanized spatial combination guided by data analysis.

Journal: Security and Communication Networks (2022)
Publication types: Research Article;
Appearance Design Method of Ceramic Art Based on VR Visualization Technology

In order to improve the effect of ceramic art appearance design, this work studies the appearance design method of ceramic art combined with vr visualization technology and builds an intelligent model.According to the needs of the industrial site and the requirements of the lighting system, the area type of the lighting area is determined in this study, and the light of the virtual ceramic product is irradiated on the target detection plane through the refraction of the lens.Based on the lambertian luminescence characteristics of the point light source virtual ceramic products and the uniform distribution of illuminance on the lighting surface, a mathematical model of the lighting system is established.Taking the realization of a rectangular lighting area with high uniformity as the main goal, the mathematical model is used to construct a system of partial differential equations of free-form surfaces, and the effect of the method in this study is verified by combining with the simulation research.The experimental research shows that the appearance design system of ceramic art based on vr visualization technology proposed in this study has a good effect and can effectively improve the interaction effect of appearance design of ceramic art.

Journal: Journal of Robotics (2022)
Publication types: Research Article;
An Effective Big Data Sharing Prototype Based on Ethereum Blockchain

Because of its many advantages, big data has been extending to various domains of science, health, education, and commerce.Despite its many applications, big data sharing typically suffers from some key issues, such as user control, lack of incentives, cost, and the right of data.This paper proposes a decentralized big data sharing prototype to improve the applications and services of big data.The method makes use of ethereum blockchain and related technologies to systematically recommend the implementation guidelines.The research provides a detailed description of the design and implementation of each sublayer of a big data system.As the method is based on blockchain technology, the key technical points are properly addressed in each of the layers.For evaluation, relevant data were collected, and functional testing was performed.A comparison was performed about the sharing frequency and blockchain consensus performance of similar platforms.The dual mining node of the proposed prototype succeeded in processing 1366 blocks and 300 messages.A comparatively satisfactory file access time in the range of 10 m to 20 s and file transmission time between 100 m and 200 s were achieved.The results obtained show that this prototype can effectively verify the feasibility of the model, the layered architecture, and the related sharing mechanism.For the functional and performance testing, practical projects were implemented and evaluated.The promising results obtained testify that the research offers a theoretical background for innovative research in the domain and specialized guidelines for practical implementation.

Journal: Scientific Programming (2022)
Publication types: Research Article;
Optimization of Rural Smart Tourism Service Model with Internet of Things

Rural smart tourism is a new tourism form supported by information technology, especially the internet of things technology.Smart tourism not only makes it easier for tourists to get diverse tourism information, but it also helps attractive sites improve their service capabilities.The optimization of the rural smart tourist service model, which is explored in this work, includes personalized recommendations of scenic sites.The main research contents of the paper are as follows: (1) a new algorithm for recommending tourism destinations with domain adaptability has been suggested.In the field of personalized recommendation of tourist attractions, most of the target domain data are unlabeled, and the model cannot be trained.When it comes to training, however, there exist source domain data sets that are completely labeled and can be used as a supplement to the target domain training data sets.(2) a personalized recommendation algorithm for tourist attractions with deep migration has been studied.Owing to the distribution difference between target data and source data, an adaptive layer is added to the convolutional neural network.The domain loss is then minimized to achieve deep feature transfer, and the model can then be trained to find scenic areas of interest to the user.Finally, the recommendation for tourist destinations with deep migration is done by examining the relationship between the target user and other users.

Journal: Security and Communication Networks (2022)
Publication types: Research Article;
Research on Public Administration and Resource Allocation Based on Blockchain and Structured Occupational Therapy

In order to explore the public administration and resource allocation based on blockchain and structured occupational therapy, this paper takes the public affairs in the prevention and control of the corona virus disease 2019 (covid-19) epidemic as an example to conduct research.On the basis of summarizing and analyzing the previous published literatures, this study expounded the research status and significance of public administration and resource allocations; elaborated the development background, current status and future challenges of blockchain, and structured occupational therapy; introduced the methods and principles of data quality collaboration model and multiparty collaboration standard management; analyzed the case background of public administration and resource allocation in the prevention and control of the covid-19 epidemic; discussed the public administration mechanism based on blockchain and structured occupational therapy; established a resource allocation method based on blockchain and structured occupational therapy; fathomed the role of the distributed ledger established by blockchain to increase the information symmetry of public administration activities; proposed a blockchain-established special machine trust for resource allocation; and finally, anatomized the data security sharing and access control mechanism based on blockchain and structured occupational therapy.The research results show that the public administration and resource allocation in this paper can effectively realize the data integration of the whole process and all departments and show the whole data and realize the traceability of the whole process.The blockchain revolutionizes the hierarchical leadership method of traditional resource allocation, shortens the distance between superiors and subordinates, makes information dissemination more fluent, and handles things more efficiently, making resource allocation ultimately form a flatter organization structure.In the original trust system of resource allocation, the blockchain and structured occupational therapy realizes the reconstruction of the trust system by preventing information tampering, using information encryption technology, and using information traceability technology.The results of this paper provide a reference for further research on the public administration and resource allocation based on blockchain and structured occupational therapy.

Journal: Occupational Therapy International (2022)
Publication types: Research Article;
Identification of an immunologic signature of lung adenocarcinomas based on genome-wide immune expression profiles

Lung cancer is one of the most common types of cancer, and it has a poor prognosis.It is urgent to identify prognostic biomarkers to guide therapy.Methods: the immune gene expression profiles for patients with lung adenocarcinomas (luads) were obtained from the cancer genome atlas (tcga) and the gene expression omnibus (geo).The relationships between the expression of 45 immune checkpoint genes (icgs) and prognosis were analyzed.Additionally, the correlations between the expression of 45 biomarkers and immunotherapy biomarkers, including tumor mutation burden (tmb), mismatch repair defects, neoantigens, and others, were identified.Ultimately, prognostic icgs were combined to determine immune subgroups, and the prognostic differences between these subgroups were identified in luad.Results: a total of 11 and nine icgs closely related to prognosis were obtained from the geo and tcga databases, respectively.Cd200r1 expression had a significant negative correlation with tmb and neoantigens.Cd200r1 showed a significant positive correlation with cd8a, cd68 , and gzmb , indicating that it may cause the disordered expression of adaptive immune resistance pathway genes.Multivariable cox regression was used to construct a signature composed of four prognostic icgs ( ido1, cd274, ctla4 , and cd200r1 ): risk score = −0.002 * ido1 +0.031 * cd274 −0.069 * ctla4 −0.517 * cd200r1 .The median risk score was used to classify the samples for the high- and low-risk groups.We observed significant differences between groups in the training, testing, and external validation cohorts.Conclusion: our research provides a method of integrating icg expression profiles and clinical prognosis information to predict lung cancer prognosis, which will provide a unique reference for gene immunotherapy for luad.

Journal: Frontiers in Molecular Biosciences (2021)
Publication types: Research Article;