syedzayyan/paper_mill_benchmark huggingface dataset:
Effect of PCI Standardized Telephone Follow-Up Service Mode on Out-of-Hospital Complications, Rehospitalization Rate, and Quality of Life of Discharged Patients with Acute Coronary Syndrome after PCI

To explore the effect of percutaneous coronary intervention (pci) standardized telephone follow-up service mode on out-of-hospital complications, rehospitalization rate, and life quality of discharged acute coronary syndrome (acs) patients after pci.Methods.From august 2020 to march 2022, 218 acs patients who were discharged after pci were included.The controls accepted routine nursing care, and the researches accepted pci standardized telephone follow-up service mode.The nursing satisfaction, rehospitalization rate, out-of-hospital complication rate, blood lipid level, and life quality score were taken as the comparisons.Results.The nursing satisfaction of study group (100.00%) was significantly higher than that of control group (88.07%).The rehospitalization rate was dramatically lower in the study group (3/109; 2.75%) than in the control group (25/109; 22.94%) ( p &lt; 0.05 ).In addition, compared with the control group, the incidence of complications (acute myocardial infarction and angina pectoris) was significantly reduced in the study group outside the hospital ( p &lt; 0.05 ).The blood lipid levels of tcho, tg, ldl-c, and hdl-c were lower in the study group than in the controls.Further, after nursing, the quality of life score of the two groups was both decreased with a higher quality of life score in the study group ( p &lt; 0.05 ).Conclusion.The application of pci standardized telephone follow-up service mode in discharged patients with acute coronary syndrome after pci can reduce out-of-hospital complications and rehospitalization rate and improve blood lipid level and life quality.

Journal: Computational and Mathematical Methods in Medicine (2022)
Publication types: Clinical Study;
Research on the Influencing Factors and Driving Paths of Public Opinions Reversed by Public Emergencies: Clear Set Qualitative Comparative Analysis Based on 30 Cases from 2014 to 2020 (QCA)

Studying the influencing factors and identifying the driving path of public opinion reversal have important practical significance for effectively avoiding the risk of public opinion reversal.Combined with the theory of actor network, the analysis shows that 7 important factors in the public opinion reversal are the antecedent conditions of public opinion reversal in public emergencies.Qualitative comparative analysis identifies the internal motivation and driving path of the reversal of online public opinion.Four core driving paths are obtained.Through the analysis of different condition combination paths, the conclusion is reached: the role of opinion leaders in reversing public opinion in public emergencies is limited; the central government must pay attention to the core role of the response; be wary of graphics and text formal dissemination; it is necessary to strengthen the check and review and standardize the management of the first issuer.

Journal: Wireless Communications and Mobile Computing (2022)
Publication types: Research Article;
Effect of Optimized Emergency Care on Treatment Rate and Prognosis of Elderly Patients with Acute Stroke in Emergency Department: A Systematic Review and Meta-Analysis

This research was to detect the treatment rate and prognosis of elderly patients with acute stroke in emergency department by the optimization of emergency care applying meta-analysis.Methods.The online databases including pub med, embase, science direct, cochrane library, china knowledge network database (cnki), china vip database, wanfang database, and china biomedical literature database (cbm) were searched.The retrieval time limit was set from the establishment of the database to the present.The data were extracted independently by two investigators.The bias of per publication was assessed following cochrane manual 5.1.0 standard.Rev man5.4 statistical software was used to analyze the collected data by meta.Results.The 8 randomized controlled trials included in this meta-analysis all reported patients’ baseline status.The meta-analysis of the rescue time of the study group and the control group ( ch 2 = 1507.80 , df = 4 , p ≤ 0.001 , and i 2 = 100 % ) showed that the emergency nursing with optimized emergency procedures can shorten the rescue of elderly acute stroke patients in the emergency department time.There are 6 literatures reporting the case fatality rate ( ch i 2 = 1.12 , df = 5 , p = 0.95 &gt; 0.05 , and i 2 = 0 % ), and the death rate of the study group was not higher than that of the control group ( z = 4.4 and p &lt; 0.0001 ).The use of optimized first aid can reduce mortality in elderly patients with acute stroke.Six articles on disability rate reported the heterogeneity of disability rate ( ch 2 = 2.88 , df = 5 , p = 0.72 &gt; 0.05 , and i 2 = 0 % ), indicating that the disability rate in the study group was lower than that in the control group ( z = 3.91 and p &lt; 0.0001 ), indicating that emergency nursing by optimizing emergency procedures can reduce the disability rate of elderly stroke patients in emergency department.Conclusion.Optimizing the emergency care process can effectively improve the emergency rate and prognosis of elderly patients with acute stroke in emergency department; however, further research with higher methodological quality and longer intervention time are needed to verify later.

Journal: Computational and Mathematical Methods in Medicine (2022)
Publication types: Meta-Analysis;
Effect of New Nursing Team Management Mode on Self-Efficacy, Compliance, and Quality of Life of Patients with Chronic Kidney Disease and Its Chain Mediating Effect

Chronic kidney disease (ckd) is one of the serious diseases that lead to a series of metabolic disorders, and its process is irreversible.In order to explore the intervention effect of the new nursing team intervention program in patients with ckd, 100 patients with ckd from may 2020 to may 2021 were randomly selected in this paper and divided into the traditional group and the combined group.The comparison of clinical nursing shows that the new nursing team management model improves the compliance, self‐management efficiency, and quality of life of patients with ckd, which is worth recommending in nursing practice.

Journal: Contrast Media & Molecular Imaging (2022)
Publication types: Research Article;
Effect of Intelligent Vital Sign Monitoring System on Postoperative Nursing Care of Severe Patients

In order to study the observation of postoperative vital sign data of critically ill patients, this paper developed a set of vital sign data acquisition system based on intelligence and realized the design of vital sign data acquisition system app based on android studio programming software, which was used to realize the information collection of vital sign data of patients.Pda is connected with a vital sign measuring equipment through bluetooth.The patient’s wristband is scanned with pda to read the patient’s information, and then the measured vital sign data are obtained automatically by measuring app.The initial alarm value is set to be greater than 1%, and it needs more than 60 and less than or equal to 120 rr interval data to judge apnea.Information collection of intelligent vital sign detection can not only save the time of nursing staff but also improve the nursing quality.

Journal: Contrast Media & Molecular Imaging (2021)
Publication types: Research Article;
Effect of Bairui Granule on Inflammatory Mediators in Induced Sputum, Leukotriene C4, and EOS in Peripheral Blood of Children with Cough Variant Asthma

To study the effect of hanchuan zupa granule combined with conventional western medicine in the treatment of children with bronchial asthma.Methods.98 cases in fengrun district people’s hospital of tangshan city from june 2018 to february 2021 were selected.The control group was given oxygen therapy, antibiotics, and aerosol inhalation of quick acting β 2 receptor agonist, glucocorticoid, and other conventional western medicine treatment, while the observation group was treated with bairui granule on the basis of the control group.The course of treatment of the two groups was 1 week.Results.After treatment, the levels of sputum il-4, il-17, neu, and ecp in the two groups decreased, and the observation group was lower than the control group ( p &lt; 0.05 ).The levels of eos, cxcr4, ltb4, and sdf-1 in peripheral blood of the two groups were lower than those in the control group ( p &lt; 0.05 ).The daytime cough, night cough, and tcm syndrome scores of the two groups were decreased, and the observation group was lower than the control group ( p &lt; 0.05 ).Conclusion.Bairui granule combined with conventional western medicine in the treatment of children with bronchial asthma, the curative effect is worthy of affirmation, can effectively improve cough symptoms, reduce eos, cxcr, ltb4, sdf-1 levels, inhibit airway inflammation, and has good clinical application value.

Journal: Computational and Mathematical Methods in Medicine (2022)
Publication types: Clinical Study;
Effect Evaluation of Bronchial Artery Embolization for Hemoptysis of Lung Cancer and Changes in Serum Tumor Markers and miR-34 Levels

The clinical efficacy, serum tumor markers, and mi r‐34 expression levels of bronchial artery embolization (bae) in patients with lung cancer with hemoptysis are investigated.92 patients with lung cancer hemoptysis treated in our hospital from january 2019 to december 2021 are randomly selected, and 92 patients are randomly divided into the conservative group and the bae group according to the number table method, with 46 patients in each group.The efficacy, overall survival (os) rate, coagulation function, hemoptysis volume, serum tumor markers, and mi r‐34 expression are compared among all groups at different time points.The experimental results show that the bae treatment can promote the expression of mi r‐34 and inhibit the expression of tumor markers, so it can improve the efficacy of patients with lung cancer hemoptysis, improve the symptoms of hemoptysis and coagulation function, and prolong the life cycle of patients.

Journal: Contrast Media & Molecular Imaging (2022)
Publication types: Clinical Study;
Diagnostic Value of Serum Heparin Binding Protein, Blood Lactic Acid Combined with hs-CRP in Sepsis and Its Relationship with Prognosis

To explore the diagnostic value of serum heparin binding protein (hbp), blood lactic acid (lac) combined with high-sensitivity c- reactive protein (hs-crp) in sepsis and its relationship with prognosis.Methods.The clinical data of 127 patients with sepsis from march 2019 to march 2021 in our hospital were retrospectively analyzed.120 outpatients undergoing physical examination in the same period in our hospital were selected as the control group.According to the severity of the disease, 127 sepsis patients were divided into the mild sepsis group (n = 45), severe sepsis group (n = 53), and septic shock group (n = 29).According to the clinical prognosis, the patients were divided into the survival group (n = 96) and death group (n = 31).Serum hbp, lac, and hs-crp levels were measured in all subjects.The roc curves of the subjects were drawn to analyze the predictive value of serum hbp, lac, and hs-crp for the prognosis of sepsis patients.Results.The levels of serum hbp, lac, and hs-crp in the sepsis group were higher than those in the control group ( p &lt; 0.05 ).With the increase of the severity of sepsis, serum hbp, lac, and hs-crp levels of patients gradually increased ( p &lt; 0.05 ).The levels of serum hbp, lac, and hs-crp in the death group were higher than those in the survival group ( p &lt; 0.05 ).The auc of serum hbp, lac, and hs-crp for predicting the prognosis of sepsis patients was 0.858 (95% ci: 0.763–0.953), 0.694 (95% ci: 0.589–0.799), and 0.843 (95% ci: 0.759–0.927).The auc of serum hbp, lac combined with hs-crp for predicting the prognosis of sepsis patients was 0.961 (95% ci: 0.000–1.000).Conclusion.The levels of serum hbp, lac, and hs-crp in patients with sepsis were significantly increased and increased with the severity of sepsis.Serum hbp, lac, and hs-crp have a good value in predicting the prognosis of patients with sepsis and worthy of clinical application.

Journal: Evidence-Based Complementary and Alternative Medicine (2021)
Publication types: Research Article;
Development and Characterization of a Nanobody against Human T-Cell Immunoglobulin and Mucin-3

Monoclonal antibodies and antibody-derived biologics are essential tools for cancer research and therapy.The development of monoclonal antibody treatments for successful tumor-targeted therapies took several decades.A nanobody constructed by molecular engineering of heavy-chain-only antibody, which is unique in camel or alpaca, is a burgeoning tools of diagnostic and therapeutic in clinic.In this study, we immunized a 4-year-old female alpaca with tim-3 antigen.Then, a vhh phage was synthesized from the transcriptome of its b cells by nested pcr as an intermediate library; the library selection for tim-3 antigen is carried out in three rounds of translation.The most reactive colonies were selected by periplasmic extract monoclonal elisa.The nanobody was immobilized by metal affinity chromatography (imac) purification with the use of a ni-nta column, sds-page, and western blotting.Finally, the affinity of tim3-specific nanobody was determined by elisa.As results, specific 15 k d bands representing nanomaterials were observed on the gel and confirmed by western blotting.The nanobody showed obvious specific immune response to tim-3 and had high binding affinity.We have successfully prepared a functional anti-human tim-3 nanobody with high affinity in vitro.

Journal: Computational and Mathematical Methods in Medicine (2022)
Publication types: Research Article;
Design of Lingnan Cultural Gene Implantation Cultural and Creative Products Based on Virtual Reality Technology

With the development of virtual reality technology, people are increasingly aware that the combination of virtual reality technology and product design can enable companies to obtain stable profits and maintain long-term competitive advantages.And design evaluation plays a pivotal role in a large number of important decisions in product development.This article takes lingnan culture and cultural products as an example, combining virtual reality technology with the design of lingnan cultural and creative products, verifies the effectiveness and rationality of the virtual evaluation system of lingnan cultural products through the evaluation of examples of lingnan cultural products, and proposes amendments to the evaluation case.This paper constructs a product design evaluation system based on virtual reality technology and designs a theoretical model vr, which is the application of virtual reality technology in product design evaluation.The pdes system expounds the idea and method of constructing the system model.This paper studies the evaluation object, evaluation content, evaluation method, evaluation platform, and manifestation of evaluation results of the lingnan cultural product virtual evaluation system and builds the framework of the lingnan cultural product virtual evaluation system.This paper studies the product display method based on virtual reality technology and realizes the three-dimensional display of products on the internet and the design of user interaction in virtual reality.In this paper, the two algorithms brsk and surf are used together, and the multiscale expression characteristics of brisk in space and the rotation invariant characteristics of surf are used.Experimental research shows that, compared with the pure brisk algorithm, the rotation performance of the method in this paper can be seen through the experimental results in this paper to have better accuracy.The method in this paper ensures the accuracy and accuracy of matching as much as possible.

Journal: Mathematical Problems in Engineering (2021)
Publication types: Research Article;
CT-ML: Diagnosis of Breast Cancer Based on Ultrasound Images and Time-Dependent Feature Extraction Methods Using Contourlet Transformation and Machine Learning

Breast diseases are a group of diseases that appear in different forms.An entire group of these diseases is breast cancer.This disease is one of the most important and common diseases in women.A machine learning system has been trained to identify specific patterns using an algorithm in a machine learning system to diagnose breast cancer.Therefore, designing a feature extraction method is essential to decrease the computation time.In this article, a two-dimensional contourlet is utilized as the input image based on the breast cancer ultrasound dataset.The sub-banded contourlet coefficients are modeled using the time-dependent model.The features of the time-dependent model are considered the leading property vector.The extracted features are applied separately to determine breast cancer classes based on classification methods.The classification is performed for the diagnosis of tumor types.We used the time-dependent approach to feature contourlet sub-bands from three groups of benign, malignant, and health control test samples.The final feature of 1200 ultrasound images used in three categories is trained based on k-nearest neighbor, support vector machine, decision tree, random forest, and linear discrimination analysis approaches, and the results are recorded.The decision tree results show that the method’s sensitivity is 87.8%, 92.0%, and 87.0% for normal, benign, and malignant, respectively.The presented feature extraction method is compatible with the decision tree approach for this problem.Based on the results, the decision tree architecture with the highest accuracy is the more accurate and compatible method for diagnosing breast cancer using ultrasound images.

Journal: Computational Intelligence and Neuroscience (2022)
Publication types: Research Article;
Correlation with Spectral CT Imaging Parameters and Occult Lymph Nodes Metastases in Sufferers with Isolated Lung Adenocarcinoma

For investigating the correlation with spectral ct imaging parameters and occult lymph nodes metastasis in sufferers with isolated lung adenocarcinoma.The clinic cases data of 352 sufferers with isolated lung adenocarcinoma from january 2019 to january 2022 were assembled.In line with whether the sufferers had occult lymph nodes metastasis, they were taken as a part in the metastasis group ( n = 172) and the nonmetastasis group.All sufferers were scanned by spectral ct with a dual‐phase contrast‐enhanced method, and the recording of spectral ct imaging parameters in arteriovenous phase, iodine concentration (ic), water concentration (wc), the slope rate of the spectral hu curve ( λ hu), the normalized iodine concentration(nic), the normalized water concentration(nwc), the normalized effective atomic number (neff‐z)], and receiver operating characteristic (roc) were employed to analyze the spectral ct imaging parameters of the arteriovenous phase.Evaluation of occult lymph nodes metastases in sufferers with isolated lung adenocarcinoma.The ic, nic, λ hu, and neff‐z in the arteriovenous phase spectral ct imaging parameters of the metastasis group were obviously smaller than that of the nonmetastasis group, and the discrepancies were statistically obvious ( p &lt; 0.05).The results of roc curve analysis manifested that the area under the curve (auc) of λ hu, ic, nic, and neff‐z in the ct parameters of the arterial phase were 0.840 (95%ci : 0.796–0.883), 0.763 (95% ci : 0.708–0.818), 0.918 (95% ci : 0.888–0.948), 0.778 (95% ci : 0.731–0.826).The aucs of λ hu, ic, nic, and neff‐z in the venous phase spectral ct parameters were 0.909 (95% ci : 0.877–0.941), 0.837 (95% ci : 0.792–0.881), and 0.980 (95% ci : 0.968–0.968), respectively.0.993), 0.792 (95% ci : 0.742∼0.842).Spectral ct imaging parameters have a certain value in evaluating occult lymph nodes metastasis in sufferers with isolated lung adenocarcinoma, which is helpful for doctors to judge the lymph nodes metastasis in sufferers with this disease before surgery.

Journal: Contrast Media & Molecular Imaging (2022)
Publication types: Research Article;
Correlation of Platelet Function with Postpartum Hemorrhage and Venous Thromboembolism in Patients with Gestational Hypertension Complicated with Diabetes

This study was aimed at investigating the correlation of platelet function with postpartum hemorrhage and venous thromboembolism (vte) in gestational hypertension patients with diabetes mellitus.Methods.A total of 93 patients with gestational hypertension complicated with diabetes treated from march 2020 to june 2021 were selected as the research group, and 56 healthy pregnant women during the same period were selected as the control group.Platelet function-related indicators (platelet count (plt), platelet volume distribution width (pdw), and mean platelet volume (mpv)) were compared between the two groups.The patients were divided into a severe group ( n = 13 ), mild group ( n = 28 ), and nonbleeding group ( n = 52 ) according to the severity of postpartum hemorrhage, and the value of combined detection of platelet function-related indicators on the severity of postpartum hemorrhage was evaluated and analyzed.According to the occurrence of vte, the patients were divided into a vte group and non-vte group to analyze the predictive value of combined detection of platelet function-related indicators for vte occurrence in patients.Results.The plt value of the study group was lower than that of the control group, while the pdw and mpv values were higher than those of the control group (all p &lt; 0.05 ).The plt value increased with the aggravation of postpartum hemorrhage, while the pdw and mpv values decreased with the aggravation of postpartum hemorrhage among the three groups with different severities of postpartum hemorrhage (all p &lt; 0.05 ).The area under the curve (auc) of plt, pdw, and mpv combination to evaluate the severity of postpartum hemorrhage in patients with gestational hypertension combined with diabetes was greater than that of plt alone and pdw alone (both p &lt; 0.05 ).The plt value was negatively correlated with the severity of postpartum hemorrhage, while pdw and mpv values were positively correlated with the severity of postpartum hemorrhage (both p &lt; 0.05 ).According to the occurrence of vte, patients were divided into the vte group ( n = 10 ) and non-vte group ( n = 83 ).The plt value of the vte group was higher than that of the non-vte group, while the pdw and mpv values were lower than those of the non-vte group (all p &lt; 0.05 ).The auc of plt, pdw, and mpv combination to predict the occurrence of vte in patients with gestational hypertension combined with diabetes was greater than that of each index alone (all p &lt; 0.05 ).Conclusion.Patients with gestational hypertension complicated with diabetes had abnormal platelet function, and the platelet function was related to postpartum hemorrhage and vte.

Journal: Computational and Mathematical Methods in Medicine (2022)
Publication types: Clinical Study;