syedzayyan/paper_mill_benchmark huggingface dataset:
Biomechanical Study Comparing Pulvertaft, Double Side-to-Side, and Locking Side-to-Side Tendon Suture Techniques.

In this study, we present a single-sided locking side-to-side (sts) suture technique as a possible alternative for the pulvertaft weave in tendon transfers.The aim of the study was to compare the biomechanical characteristics of the single-sided locking sts reconstruction with pulvertaft and double-sided nonlocking sts reconstructions.Methods twenty-four human cadaveric extensor digitorum communis tendons and 24 flexor digitorum superficialis tendons were randomly assigned to 1 of 3 groups, resulting in a total of 8 flexor tendons and 8 extensor tendons per group: pulvertaft, double-sided nonlocking sts, and single-sided locking sts reconstructions.Load to failure was measured with a tensile testing machine.Increase in cross-sectional area was used as a measure of bulkiness at the reconstruction site.Results in extensor tendons, single-sided locking sts reconstructions showed a higher load to failure than pulvertaft reconstructions, whereas no difference was found in load to failure between single-sided locking and double-sided nonlocking sts reconstructions.In flexor tendons, single-sided locking sts reconstructions showed a higher load to failure than pulvertaft reconstructions.However, load to failure of single-sided locking sts reconstructions was less than double-sided nonlocking sts reconstructions.In both extensor and flexor tendons, the percent increase in cross-sectional area at the reconstruction site was higher in pulvertaft reconstructions than single-sided locking sts reconstructions, whereas no difference was found between single-sided locking sts and double-sided nonlocking sts reconstructions.Conclusions single-sided locking and double-sided nonlocking sts reconstructions are suitable alternatives to the pulvertaft technique for tendon transfers owing to a higher strength and less bulkiness.Because load to failure of both sts reconstructions did not differ in extensor tendon transfers, the single-sided locking sts reconstruction seems especially suitable for extensor tendon transfers.Clinical relevance this study provides anatomical evidence that the single-sided locking sts reconstruction yields a higher strength and is less bulky than the pulvertaft reconstruction in tendon transfers.

Journal: The Journal of hand surgery (2021)
Publication types: Journal Article
High Prevalence of Undocumented SARS-CoV-2 Infections in the Pediatric Population of the Tyrolean District of Schwaz.

Complementing the adult seroprevalence data collected at the time of the rapid sars-co v-2 mass vaccination in the district of schwaz in 2021, we set out to establish the seroprevalence of sars-co v-2 among the pediatric population of the district.A total of 369 children, mean age 9.9 (sd 3.4), participated in the study, answering a structured questionnaire on the history of sars-co v-2 infection, household contacts, symptoms and history of vaccination.We determined binding and neutralizing antibody levels using plasma samples provided.We estimated the overall prevalence of sars-co v-2 infection in the general pediatric population at the time of the study using the census data from statistik austria and daily reports of officially confirmed cases.Excluding study participants who reported a history of pcr-confirmed infection, the age-standardized seroprevalence of previously unknown sars-co v-2 infection among the general pediatric population of the district was 27% (95% ci: 26.1-27.8).Adding this to the officially documented cases, the true overall prevalence was 32.8% (95% ci: 31.9-33.6) in contrast to the officially documented 8.0% (95% ci: 7.5-8.5) by june 2021.This translated into a proportion of 75.7% (95% ci: 74.4-77.0) of cases being officially undocumented, suggesting a high extent of silent sars-co v-2 infections in the pediatric population and possibly silent transmission.

Journal: Viruses (2022)
Publication types: Journal Article
Primary splenic lymphoma on top of intrahepatic splenosis: A unique case report.

Solid organ splenosis is a challenging diagnosis with many atypical imaging features that can overlap with neoplastic masses of the affected organ.We present a sporadic case of intrahepatic splenosis in a 68-year-old woman with transformation into a low-grade b cell lymphoma.Initial cross-sectional imaging suggested focal nodular hyperplasia (fnh) ruled out on contrast-enhanced magnetic resonance imaging (mri) using a hepatobiliary-specific contrast agent.A tc-99m sulfur colloid scan was negative.The final diagnosis was confirmed by a needle-guided biopsy revealing intrahepatic splenosis with transformation into a low-grade b cell lymphoma.

Journal: Radiology case reports (2022)
Publication types: Case Reports;Journal Article
Oral sequential therapy in the treatment of post-surgical epidural abscess and subdural empyema.

The management of post-surgical subdural empyema and subdural abscess is not standardised.The objective was to analyse the efficacy and safety of oral sequential therapy (ost).Methods retrospective observational study in a tertiary hospital in vigo (spain).We included adult patients with subdural abscess or epidural empyema with microbiological isolation.Clinical and demographic variables, isolated microorganisms and treatment regimens were included, as well as mortality and adverse effects during the follow-up period.Results thirty patients were reviewed, two died due to causes other than infection.Six-month recurrence rate was 2/28 and all other patients (26/28) had clinical cure at the end of the treatment.The commonest isolated microorganisms were gram-positive, especially staphylococcus aureus.The most widely used oral antibiotic was trimethoprim-sulfamethoxazole (80%).No side effects related to oral treatment were observed.Conclusion after adequate source control, ost can be a safe practice in the management of post-surgical epidural abscess and subdural empyema.

Journal: Infection (2022)
Publication types: Journal Article;Observational Study
A unipolar compact nanosecond pulsed power supply with high power factor for dielectric barrier discharge applications.

A high voltage with a very short duration and fast rising time is beneficial to generate uniform and diffuse plasma in dielectric barrier discharge (dbd) loads, and a power supply with a high power factor (pf) can reduce the impact on the power grid.According to two requirements, a unipolar high voltage pulsed power supply with power factor correction (pfc) is proposed in this paper.The power supply consists of a unipolar pulse high voltage generating unit, a pfc unit, and a driving circuit.By introducing a feedback clamping diode and a reverse current blocking diode in a flyback converter, repetitive nanosecond pulses are generated in the unipolar pulse high voltage generating unit.Because a discontinuous current mode strategy is adopted in the pfc unit and the driving signal is shared by the two units, a compact structure of the power supply is achieved, and a high pf is obtained.To validate the proposed pulsed power supply, an experimental setup is built for a dbd excimer lamp.The results show that the proposed power supply has the capability of not only providing a unipolar nanosecond pulse high voltage for the dbd excimer lamp but also achieving pf close to 1 and total harmonic distortion of less than 24%.

Journal: The Review of scientific instruments (2022)
Publication types: Journal Article
Functionalization of Alpha-Lactalbumin by Zinc Ions.

Alpha-lactalbumin (α-la) and binding of zinc cations to protein were studied.Molecular characteristics of protein was determined by maldi-tof/ms and electrophoresis sds-page, and also, for complexes, it was determined by spectroscopic techniques (atr-ft-ir and raman) and microscopic techniques (sem along with an edx detector and also tem).The p h dependence of zeta potential of α-la was determined in saline solution.The zinc binding to the protein mechanism was investigated; zinc binding to protein kinetics, the molecular modeling by the dft method, and electron microscopy (sem and tem) for microstructure observation were performed.The experiments performed indicate a quick binding process (equilibrium takes place after 2 min of incubation) which occurs onto the surface of α-la.Zinc cations change the conformation of the protein and create spherical particles from the morphological point of view.Dft studies indicate the participation of acidic functional groups of the protein (aspartic acid and glutamic acid residues), and these have a decisive influence on the interaction with zinc cations.Application studies of general toxicity and cytotoxicity and bioavailability were conducted.

Journal: ACS omega (2022)
Publication types: Journal Article
Minimizing the Reorganization Energy of Cobalt Redox Mediators Maximizes Charge Transfer Rates from Quantum Dots.

Light-induced charge separation is at the very heart of many solar harvesting technologies.The reduction of energetic barriers to charge separation and transfer increases the rate of separation and the overall efficiency of these technologies.Here we report that the internal reorganization energy of the redox acceptor, the movement of the atoms with changing charge, has a profound effect on the charge transfer rates from donor quantum dots.We experimentally studied and modelled with marcus theory charge transfer to cobalt complexes that have similar redox potentials covering 350 m v, but vastly different reorganization energies spanning 2 e v.While the driving force does influence the electron transfer rates, the reorganization energies had a far more profound effect, increasing charge transfer rates by several orders of magnitude.Our studies suggest that careful design of redox mediators to minimize reorganization energy is an untapped route to drastically increase the efficiency of quantum dot applications that feature charge transfer.

Journal: Angewandte Chemie (International ed. in English) (2022)
Publication types: Journal Article
Systematic Review of Health Promotion Frameworks Focused on Health in the Postpartum Period.

To systematically review the scope and development of frameworks to promote health during the postpartum period.Data sources we searched pub med, cinahl, and american psychological association psyc info during may 2021.Study selection we included english-language, peer-reviewed articles focused on frameworks for health promotion in the postpartum period.We placed no time limit on publication date.Our search resulted in 2,355 articles after we removed duplicates.After excluding articles based on titles and abstracts, we conducted full-text reviews of 23 articles.Three articles met inclusion criteria and addressed the following frameworks: integrated perinatal health framework, perinatal maternal health promotion model, and maternal self-care framework.Data extraction we extracted data into analytic tables that included categories for the scope, such as time frame, and criteria for the level of development of the frameworks, including the origins, concept definitions and theoretical linkages among concepts, and evidence of application in research or practice.Data synthesis the three frameworks described in the articles included in our review covered various periods, including the reproductive life span, the first year after birth, and the first 6 weeks after birth.Overall, the frameworks were comprehensive.Most key concepts in the frameworks were defined, and some degree of relationships linking concepts was specified.Empirical referents were provided for most but not all concepts in the frameworks.Developers of the three frameworks elaborated on application in practice or health services, but only the developers of the maternal self-care framework indicated how their framework might be used in research.The integrated perinatal health framework and maternal self-care framework were partially derived from existing general theories; the methods used to develop the perinatal maternal health promotion model were less clear.Conclusion the frameworks met most criteria and together provided a comprehensive strategy for health promotion during the postpartum period.Elaboration of the frameworks for application in research is needed.

Journal: Journal of obstetric, gynecologic, and neonatal nursing : JOGNN (2022)
Publication types: Journal Article;Review;Systematic Review
Bilateral pelvic crescent fracture combined with left acetabular fracture: A case report.

Introduction crescent fracture-dislocations are subtype of lateral compression fractures of the pelvic ring, which usually occur following high-velocity impacts.Bilateral crescent fractures are rare entities, with a limited number of cases reported in the literature.Of those reported, none were combined with an acetabulum fracture.Presentation of case the case involves a 49-year-old male, who presented to the trauma unit after a motor vehicle collision and sustained a bilateral crescent pelvic fracture combined with a left acetabulum fracture.The patient was resuscitated and managed initially according to the advanced trauma life support (atls) protocol then staged fixation of his pelvic and acetabulum fractures was carried out.Conclusion bilateral crescent fractures of the pelvis combined with acetabulum fractures constitute a rare injury.Given their rarity, a standard of care is lacking and has not been described yet.Staged surgical stabilization of such combined injuries is recommended, and may contribute to a better outcome.

Journal: International journal of surgery case reports (2022)
Publication types: Case Reports;Journal Article
Rhino-orbito-cerebral mucormycosis infection in a 4-year-old Egyptian girl.

Rhino-orbital cerebral mucormycosis is a rare, potentially fatal fungal infection that usually affects diabetic and immunocompromised adults.Recently, an increase in the frequency of this infection in children has been reported, especially in neutropenic patients and premature babies.In this article, we are reporting a case of rhino-orbital cerebral mucormycosis in a 4-year-old girl with a newly diagnosed diabetes mellitus.Tissue biopsy, fungal culture, and imaging were used to confirm the diagnosis.The infection was successfully treated with combined surgical debridement and antifungals.

Journal: Medical mycology case reports (2022)
Publication types: Case Reports;Journal Article
Nonnative Cattle Ownership, Diet, and Child Height-for-Age: Evidence from the 2011 Uganda Demographic and Health Survey.

In underresourced settings where domestic animals and children often cohabitate, there is limited evidence about the net impact of domestic animal ownership on child health.We analyzed the 2011 uganda demographic and health survey to determine whether household ownership of native cattle, goats, sheep, chickens, pigs, and nonnative cattle was associated with child height-for-age z-scores (haz), and to assess the influence of diet on this association in rural and urban environments.Using weighted multivariable linear regression, we found that nonnative cattle ownership was positively associated with haz in rural children 0 to < 2 years of age (+1.32 standard deviations [sd], 95% confidence interval [ci] = 0.2-2.5) and 2 to < 5 years of age (+0.58 sd, 95% ci = 0.003-1.2), and urban children 2 to < 5 years of age (+1.08 sd, 95% ci = 0.38-1.8).Sheep ownership was positively associated with haz in rural children 2 to < 5 years of age (+0.29 sd, 95% ci = 0.002-0.58) and goat ownership was positively associated with haz in rural children 0 to < 2 years of age (+0.27 sd, 95% ci = 0.003-0.55).We observed no other significant associations.Children who lived in households that owned nonnative cattle consumed dairy more frequently; however, the relationship between child haz and nonnative cattle ownership was not mediated by child dairy consumption.These findings suggest that domestic animal ownership may not be detrimental to child haz, and that nonnative cattle ownership is beneficial for child haz through pathways other than dairy consumption.

Journal: The American journal of tropical medicine and hygiene (2017)
Publication types: Journal Article
INPP4B exerts a dual role in gastric cancer progression and prognosis.

Inositol polyphosphate 4-phosphatase type ii (inpp4b) negatively regulates pi3k-akt signalling and plays diverse roles in different types of cancer, but its role in gastric cancer (gc) is still unknown.Our study aimed to investigate the function and clinical relevance of inpp4b in gc.Inpp4b expression was detected in gc tissues and nontumour tissues.The effect of inpp4bon the phenotypic changes of ags and bgc-823 cells was investigatedin vitro.The activation of serum and glucocorticoid-regulated kinase 3 (sgk3) and akt were used to evaluate the specific mechanistic function of inpp4bin gc cells.The messenger rna (m rna) and protein expression levels of inpp4bwere decreased in gc tissues compared with nontumour tissues.Inpp4b expression was associated with tumour-node-metastasis (tnm) stage and histopathological differentiation.In addition, high inpp4b expression in gc patients with large tumour size/low-undifferentiated/tnm's iii-iv stage was correlated with a poor prognosis but it was correlated with a better prognosis in patients with small tumour size/high-moderate differentiated/tnm's i-ii stage patients.In addition,inpp4bknockdown inhibited proliferation, clonal formation and migration and promoted cell apoptosisin vitro, while inpp4boverexpression led to the opposite effects.Mechanistically, we found that inpp4boverexpression enhanced the phosphorylation of sgk3 (p-sgk3) in ags cells, whereas inpp4bknockdown enhanced the p-akt level in bgc823 cells.These findings suggested that the expression of inpp4b in gc is lower than that in normal tissues.Based on stratification survival analysis andin vitrocell experiments,inpp4bmay play dual roles as an oncogene and tumour suppressor gene in different tissue grades and clinical stages.

Journal: Journal of Cancer (2021)
Publication types: Journal Article
Phenotypic plasticity is aligned with phenological adaptation on both micro- and macroevolutionary timescales.

In seasonally variable environments, phenotypic plasticity in phenology may be critical for adaptation to fluctuating environmental conditions.Using an 18-generation longitudinal dataset from natural damselfly populations, we show that phenology has strongly advanced.Individual fitness data suggest this is likely an adaptive response towards a temperature-dependent optimum.A laboratory experiment revealed that developmental plasticity qualitatively matches the temperature dependence of selection, partially explaining observed advance in phenology.Expanding our analysis to the macroevolutionary level, we use a database of over 1-million occurrence records and spatiotemporally matched temperature data from 49 swedish odonate species to infer macroevolutionary dynamics of phenology.Phenological plasticity was more closely aligned with adaptation for species that have recently colonised northern latitudes, but with higher phenological mismatch at lower latitudes.Our results show that phenological plasticity plays a key role in microevolutionary dynamics within a single species, and such plasticity may have facilitated post-pleistocene range expansion in this insect clade.

Journal: Ecology letters (2022)
Publication types: Letter
Directed evolution of maltogenic amylase from Bacillus licheniformis R-53: Enhancing activity and thermostability improves bread quality and extends shelf life.

Maltogenic amylase from bacillus licheniformis r-53 improves bread quality and shelf life.Here, we constructed a random mutation library of this enzyme using error-prone pcr to identify mutants with higher activity and thermostability, then screened the key point mutations.Mutant v296f/k418i had 2.16 times the specific activity of the wild-type enzyme, and its temperature for optimum activity increased from 60 to 65 °c.Moreover, it maintained > 60% residual activity after heating at 55 to 80 °c for 30 min.Mixolab experiments showed that treatment with 45 ppm v296f/k418i mutant maltogenic amylase had better effects in delaying dough recrystallization than 60 ppm wild-type enzyme.During bread storage, 45 ppm v296f/k418i was more effective in reducing hardness, improving elasticity, and maintaining sensory than 60 ppm wild-type enzyme.Directed evolution of maltogenic amylase significantly improved its activity and thermostability; the mutant enzyme is conducive to improving bread quality and extending its shelf life.

Journal: Food chemistry (2022)
Publication types: Journal Article
Evaluation of macular microvasculature and foveal avascular zone in patients with retinal vein occlusion using optical coherence tomography angiography.

S to quantitatively evaluate the vessel density of macular microvasculature, choriocapillary, and foveal avascular zone (faz) in both eyes of patients with unilateral retinal vein occlusion (rvo) using the optical coherence tomography angiography (octa) compared with the normal controls.Methods a retrospective review was conducted on 72 patients with unilateral rvo (72 eyes with rvo and 72 rvo fellow eyes) and 72 healthy individuals (72 normal control eyes).The 3 × 3 mm macular angiogram was acquired using the octa.The vessel densities of the retinal superficial capillary plexus (scp), deep capillary plexus (dcp), and choriocapillary plexus (ccp) were measured, and faz was quantified.Results the rvo eyes compared to their fellow eyes, and the fellow eyes compared to the normal controls, showed a significantly lower vessel density in both the scp and dcp in the whole image and parafovea (p 0.05).No significant differences between the rvo eyes and the fellow eyes in the faz area and perimeter (p > 0.05) were observed, while the acircularity index in the rvo eyes was significantly higher than the fellow eyes (p < 0.05).Additionally, the fd-300 in the rvo eyes was significantly lower than their fellow eyes (p < 0.05).Conclusions the octa reveals that the macular microvasculature of the rvo fellow eyes can be impaired in both the superficial and deep retinal layer as well as the choriocapillary, suggesting the influence of systemic factors in the development of rvo.

Journal: International ophthalmology (2022)
Publication types: Journal Article
Application of Genetic Optimization Algorithm in Financial Portfolio Problem.

In order to address the application of genetic optimization algorithms to financial investment portfolio issues, the optimal allocation rate must be high and the risk is low.This paper uses quadratic programming algorithms and genetic algorithms as well as quadratic programming algorithms, matlab planning solutions for genetic algorithms, and genetic algorithm toolboxes to solve markowitz's mean variance model.The mathematical model for introducing sparse portfolio strategies uses the decomposition method of penalty functions as an algorithm for solving nonconvex sparse optimization strategies to solve financial portfolio problems.The merging speed of the quadratic programming algorithm is fast, and the merging speed depends on the selection of the initial value.The genetic algorithm performs very well in global searches, but local search capabilities are insufficient and the pace of integration into the next stage is slow.To solve this, using a genetic algorithm toolbox is quick and easy.The results of the experiments show that the final solution of the decomposition method of the fine function is consistent with the solution of the integrity of the genetic algorithm.67% of the total funds will be spent on local car reserves and 33% on wine reserves.When data scales are small, quadratic programming algorithms and genetic algorithms can provide effective portfolio feedback, and the method of breaking down penalty functions to ensure the reliability and effectiveness of algorithm combinations is widely used in sparse financial portfolio issues.

Journal: Computational intelligence and neuroscience (2022)
Publication types: Journal Article