syedzayyan/paper_mill_benchmark huggingface dataset:
Joint position statement of the Societat Catalana de Digestologia and the Societat Catalana de Radiologia on gastroenterologist-led ultrasound in Catalonia.

Over recent years, ultrasonography has been used increasingly in various medical specialties and is now an indispensable diagnostic tool.In gastroenterology, bedside or point-of-care ultrasound allows the early diagnosis and monitoring of multiple intraabdominal conditions.Ultrasound guidance is also highly useful in certain therapeutic procedures, increasing procedural safety.Ultrasound is a non-invasive technique but has the drawback of being very operator dependent.Therefore, it is necessary to ensure that the professionals who perform ultrasonography have a sufficient level of training in the technique.In catalonia, abdominal ultrasound is usually carried out by radiologists and has not yet been incorporated as an investigation performed by gastroenterologists.In view of this, the societat catalana de radiologia and the societat catalana de digestologia judged it necessary to develop a consensus framework document on ultrasound use and training for gastroenterologists.The document establishes the suggested format for training, the appropriate indications, the minimum material requirements and appropriate documentation of the procedure to ensure that gastroenterologist-performed ultrasound is useful and safe.

Journal: Gastroenterologia y hepatologia (2022)
Publication types: Journal Article;Practice Guideline
How Does the Change of Information Source Affect Residents' Risk Attitudes?

Using data from the china family panel studies (cfps), this paper investigates the effects of internet use on residents' risk attitudes.Both generalized ordered logit model and logit model are used to identify the effects of internet use.The results reveal an association between internet use and increases in both subjective and objective risk preferences that remains even after we adjust for possible endogeneity.The heterogeneity analysis also reveals that these impacts are different among groups with different reasons for internet use and different personal characteristics.Our study expands the research on the effects of internet on people's concepts from the micro perspective and suggests that while promoting the application of information technology we should also pay attention to the individual characteristics of residents so that we can better share the "digital dividend" brought by the popularization of information technology in the whole society.

Journal: Frontiers in psychology (2022)
Publication types: Journal Article
Cannabidiol and Beta-Caryophyllene in Combination: A Therapeutic Functional Interaction.

Cannabis contains over 500 distinct compounds, which include cannabinoids, terpenoids, and flavonoids.However, very few of these compounds have been studied for their beneficial effects.There is an emerging concept that the constituents of the cannabis plant may work in concert to achieve better therapeutic benefits.This study is aimed at determining if the combination of a minor cannabinoid (cannabidiol, cbd) and a terpene (beta-caryophyllene, bcp) works in concert and if this has any therapeutic value.We used an inflammatory pain model (formalin) in mice to test for any functionality of cbd and bcp in combination.First, we determined the analgesic effect of cbd and bcp individually by establishing dose-response studies.Second, we tested the analgesic effect of fixed-ratio combinations and monitored any adverse effects.Finally, we determined the effect of this combination on inflammation.The combination of cbd and bcp produces a synergistic analgesic effect.This effect was without the cannabinoid receptor-1 side effects.The analgesic effect of cbd and bcp in combination involves an inflammatory mechanism.The combination of these two constituents of the cannabis plant, cbd and bcp, works in concert to produce a therapeutic effect with safety profiles through an inflammatory mechanism.

Journal: International journal of molecular sciences (2022)
Publication types: Journal Article
Finding Predictors of Azathioprine-Induced Pancreatitis in Patients With Inflammatory Bowel Disease.

S azathioprine (aza)-induced pancreatitis (aip) is a common, idiosyncratic adverse effect whose incidence and risk factors data in inflammatory bowel disease (ibd) patients are not fully clarified.We aimed to establish the incidence, clinical course and identify risk factors for aip.Methods a retrospective study including all ibd patients on aza between january 2013 and july 2020 was conducted.Patients with aip were considered.Results azathioprine-induced pancreatitis occurred in 33 patients (7.5%; 442 patients on aza).The mean time receiving aza until aip was 25 days, with a mean dose of 88 mg.All patients had a mild course of disease, which resolved with suspension of aza and with no complications.Smoking (p = 0.02), single daily dose of aza (p < 0.001), and concomitant budesonide (p = 0.001) were risk factors for aip.In multivariate analysis, concomitant treatment with budesonide (odds ratio, 5.3; p = 0.002) and single daily dose of aza (odds ratio, 3.8; p = 0.002) were the only predictors of aip.Conclusions although aip was a relatively common adverse effect, it presented a mild course in all patients.Smoking, concomitant use of budesonide, and single-dose regimen of aza should be avoided in ibd patients treated with aza.

Journal: Pancreas (2022)
Publication types: Journal Article
Enhanced photocatalytic Hg0oxidation activity of iodine doped bismuth molybdate (Bi2MoO6) under visible light.

The application of photocatalytic hg0oxidation under visible light is an up-and-coming method to solve the problem of energy shortage and environmental pollution.In this work, iodine doped bi2mo o6nanomaterials were prepared by one-step solvothermal method.The photocatalytic oxidation efficiency was greatly improved by iodine doping from 35.5% to 95.2% in the n2+ 4% o2atmosphere under visible light.The main reason was that iodine doping decreased the band gap of the catalyst, expanded the optical response range and intensity, sped up the separation rate of photoinduced carriers and reduced the recombination rate.In addition, the flue gas components of so2and no played a promoting role in mercury removal.Iodine doped bi2mo o6had good stability and still maintained high mercury removal efficiency after 5 cycles.Density functional theory (dft) calculations and experiments demonstrated that iodine doping changed the valence band and conduction band of the catalyst, making superoxide ions, hydroxyl radicals and photoinduced hole become the active species of the catalytic reaction.

Journal: Journal of colloid and interface science (2022)
Publication types: Journal Article
Treatment of Severe Refractory Thrombocytopenia in Brucellosis with Eltrombopag: A Case Report.

Brucellosis is a zoonotic disease.Severe refractory thrombocytopenia caused by brucellosis is very rare and easily misdiagnosed.We reported a 5-year-old girl who developed severe refractory thrombocytopenia secondary to brucellosis.The first-line treatment including corticosteroids and intravenous immunoglobulin did not elevate her platelets, but eltrombopag worked well and her platelet count recovered rapidly.

Journal: The Pediatric infectious disease journal (2022)
Publication types: Case Reports;Journal Article;Research Support, Non-U.S. Gov't
Robotic versus open oncological gastric surgery in the elderly: a propensity score-matched analysis.

Although there is no agreement on a definition of elderly, commonly an age cutoff of ≥ 65 or 75 years is used.Even if robot-assisted surgery is a validated option for the elderly population, there are no specific indications for its application in the surgical treatment of gastric cancer.The aim of this study is to evaluate the safety and feasibility of robot-assisted gastrectomy and to compare the short and long-term outcomes of robot-assisted (rg) versus open gastrectomy (og).Patients aged ≥ 70 years old undergoing surgery for gastric cancer at the department of surgery of san donato hospital in arezzo, between september 2012 and march 2017 were enrolled.A 1:1 propensity score matching was performed according to the following variables: age, sex, bmi, asa score, comorbidity, t stage and type of resection performed.43 og were matched to 43 rg.The mean operative time was significantly longer in the rg group (273.8 vs.193.5 min, p < 0.01).No differences were observed in terms of intraoperative blood loss, an average number of lymph nodes removed, mean hospital stay, morbidity and mortality.Og had higher rate of major complications (6.9 vs.16.3%, or 2.592, 95% ci 0.623-10.785, p = 0.313) and a significantly higher postoperative pain (0.95 vs.1.24, p = 0.042).Overall survival (p = 0.263) and disease-free survival (p = 0.474) were comparable between groups.Robotic-assisted surgery for oncological gastrectomy in elderly patients is safe and effective showing non-inferiority comparing to the open technique in terms of perioperative outcomes and overall 5-year survival.

Journal: Journal of robotic surgery (2021)
Publication types: Journal Article
Recovering from COVID-19 - A Process Characterised by Uncertainty: A Qualitative study.

To obtain a deeper understanding of the lived experiences of patients with covid-19, the recovery process and consequences for everyday life 6 months after hospital discharge.Design an explorative qualitative study using individual interviews.Subjects a purposive sampling was applied to recruit persons who had received inpatient hospital care, were discharged approximately 6 months previously, were of working age and had persistent self-reported symptoms at a 3-month follow-up appointment.Methods semi-structured interviews were conducted with 15 participants (10 men, 5 women), which were then transcribed and analysed with inductive thematic analysis.Results three themes were identified: "status of recovery - two steps forward, one step back", "remaining symptoms caused limitations in everyday life" and "strategies for recovery".Participants indicated the recovery process through 6 months after discharge was a challenging road, often involving setbacks.A wide range of persistent, fluctuating, or new symptoms negatively impacted many areas of daily life, with fatigue and lack of energy being especially prominent.Participants used a variety of strategies to cope and recover.Conclusion this study increases our knowledge of the lived experiences of covid-19 based individual experiences.Unexpected symptoms in the recovery process were described and not always possible to forecast.

Journal: Journal of rehabilitation medicine (2022)
Publication types: Journal Article
The hepatitis B care cascade using administrative claims data, 2016.

S monitoring care and treatment for persons with chronic hepatitis b (chb) is essential for demonstrating progress in achieving national elimination goals.We sought to evaluate insurance claims data as a source for monitoring progression along the chb care cascade.Study design longitudinal evaluation from diagnosis to treatment among commercially insured enrollees with chb.Methods we used standardized procedure and diagnosis codes to identify enrollees (≥ 18 years) with chb in large insurance claims databases to describe the chb care cascade from 2008 to 2016.Linkage to care was defined as procedure codes for liver fibrosis assessment (alanine aminotransferase in conjunction with either hepatitis b virus dna or hepatitis b e-antigen) more than 12 months after chb diagnosis.Treatment was defined as a claim for any chb prescription.We analyzed factors associated with linkage to care and treatment using unadjusted logistic regression and evaluated rates of diagnosis, linkage to care, and treatment over time.Results of 16,644 individuals with chb, 6004 (36%) were linked to care and 2926 (18%) were treated.Persons coinfected with hiv (odds ratio [or], 0.46; 95% ci, 0.36-0.59) or hepatitis c (or, 0.50; 95% ci, 0.34-0.73) were less likely to be linked to care, and persons coinfected with hiv (or, 0.29; 95% ci, 0.19-0.44) were less likely to be treated.From 2009 to 2015, there was a significant decrease in chb diagnoses but no change in the proportion linked to care and treatment.Conclusions we identified gaps in linkage to care and treatment in commercially insured adults with chb.

Journal: The American journal of managed care (2020)
Publication types: Journal Article;Research Support, U.S. Gov't, P.H.S.
Urethral caruncle in penile urethra in a young male.

Urethral caruncles are seen almost exclusively in women.When these lesions are diagnosed in a male patient, he is likely to undergo unnecessary radical treatment mistaking a urethral caruncle for a malignant urethral neoplasm.Hence, a proper histopathological diagnosis is mandatory before deciding the final treatment.We report a case of fleshy masses in the penile urethra of a young male patient.Simple excision was performed and the histopathology revealed a urethral caruncle of the angiomatous variety.

Journal: Indian journal of urology : IJU : journal of the Urological Society of India (2022)
Publication types: Case Reports;Journal Article
Ethanol Extracts of Rice Bran and Whole Grain Adlay Seeds Mitigate Colonic Inflammation and Damage in Mice with Colitis.

Ulcerative colitis (uc) is a chronic inflammatory bowel disease with frequent relapsing inflammation in the colon.Whole grains have been promoted as healthy and sustainable foods; however, the use of whole gains in uc is inconclusive.The aim of this study was to investigate the effects of ethanol extracts of rice bran (rbe) and whole-grain adlay seeds (ade) on inflammation, oxidative stress, and colonic damage in uc.Male c57bl/6jnarl mice were intra-rectal injected twice with 2,4-dinitrobenzene sulfonic acid to induce (day 0) and reactivate (day 21) uc.Control mice were fed ain-93m diet (r group) and injected with a vehicle.Uc mice were fed ain-93m diet (uc group) supplemented with rbe (rbe group) or ade (ade group) for 21 days.The results showed that the uc group had an increased disease activity index, plasma interleukin (il)-6 and glutathione levels, microscopic injury scores, and inflammatory cytokine and chemokine levels in the colon and decreased colonic claudin-4 compared to the r group.Rbe and ade supplementation significantly reduced uc-elevated plasma il-6 and colonic glutathione and pro-inflammatory cytokines and a chemokine.In addition, rbe and ade supplementation significantly decreased t-helper-cell-associated cytokines in the plasma and colon.Moreover, rbe supplementation increased colonic il-10 and tight junction protein claudin-4 levels, and ade supplementation alleviated diarrhea in uc mice.In conclusion, these results suggest that rbe and ade may mitigate colonic inflammation, oxidative stress, and damage in uc relapse.

Journal: Nutrients (2022)
Publication types: Journal Article
Ruptured cerebral mycotic aneurysm in a left ventricular assist device patient with bacteremia.

A 50-year-old male with a history of nonischemic dilated cardiomyopathy presented in cardiogenic shock and ultimately underwent durable left ventricular assist device implantation.He recovered well initially but developed persistent bacteremia.His indwelling pacemaker leads were extracted due to evidence of vegetation.Shortly thereafter, around 3 months post-left ventricular assist device, he succumbed to a massive intracranial hemorrhage due to ruptured cerebral mycotic aneurysm.This case highlights the potential importance of brain imaging in left ventricular assist device patients with persistent bacteremia to avoid this likely catastrophic complication.

Journal: The International journal of artificial organs (2021)
Publication types: Case Reports;Journal Article
Esthetic complications in implant dentistry.

Esthetic complications in implant dentistry have become a significant consideration for patients and practitioners.This review presents an appraisal on the current knowledge of the physiological peri-implant soft-tissue dimensions and factors that may compromise peri-implant tissue esthetics.Factors such as papilla fill adjacent to the implant and midfacial mucosal height are critical parameters that determine the esthetic success of implant-supported restorations.Papilla fill adjacent to a single dental implant appears to depend upon the clinical attachment level of the neighboring tooth.A horizontal inter-implant distance of at least 3 mm is necessary to ensure optimal interproximal mucosal embrasure between two adjacent implants in the anterior maxilla.In cases where implants cannot be placed at least 3 mm apart, a single implant with a cantilever bridge should be considered.Buccolingual implant positioning plays a major role in midfacial mucosal height.Soft-tissue volume grafting following immediate implant placement in the presence of a thin soft-tissue phenotype or simultaneous to surgical peri-implantitis therapy might help to overcome facial mucosa recession.

Journal: Periodontology 2000 (2022)
Publication types: Journal Article;Research Support, Non-U.S. Gov't;Review
Two-dimensional ultrasound and two-dimensional shear wave elastography on femoral and saphenous neuropathy in patients with type 2 diabetes mellitus.

This study aims to examine the value of two-dimensional (2d) ultrasound and two-dimensional shear wave elastography (2d-swe) in evaluating femoral nerve (fn) and saphenous nerve (sn) neuropathy in patients with type 2 diabetes mellitus (t2dm).Materials and methods according to the diabetic peripheral neuropathy (dpn) diagnostic criteria, 60 patients with t2dm were enrolled and divided into 35 t2dm patients without dpn (non-dpn group) and 25 t2dm patients with dpn (dpn group).The control group consisted of another 15 healthy volunteers.The width, thickness, cross-sectional area (csa), and perimeter of the fn and sn in the lower extremities were measured with 2d ultrasound.The average shear wave velocity (swv) of the fn and sn was measured by 2d-swe.Parameters of the left and right lower extremities were compared in each group, and the above parameters were compared among groups.The correlations between ultrasonographic and laboratory parameters were evaluated, and the independent influencing factors of swv of the fn and sn were analyzed.Results the width, thickness, csa, perimeter, and swv of fn and sn in the dpn group were greater than those in the non-dpn groups and control group (p< 0.05).The width, thickness, csa, perimeter, and swv of the fn and sn in the non-dpn group were greater than those in the control group (p< 0.05).The csa of fn was positively correlated with fpg, hb a1c, and tg (r= 0.34-0.69,p< 0.01).The perimeter of fn was positively correlated with fpg, hb a1c, and tg (r= 0.37-0.68,p< 0.01).The perimeter of the fn was negatively correlated with ig f-1 (r= -0.31,p< 0.05).The csa of the sn was positively correlated with fpg and tg (r= 0.26-0.42,p< 0.05).The perimeter of the sn was positively correlated with fpg and tg (r= 0.37-0.39,p< 0.01).The swv of fn and sn were positively correlated with fpg and tg (r= 0.35-0.57,p< 0.01;r= 0.43-0.49,p< 0.01).Fpg and tg were independent influencing factors of the swv of the fn and sn (p< 0.05).Conclusion 2d ultrasound and 2d-swe could be used to non-invasively, objectively, and accurately evaluate the abnormal changes of the fn and sn in patients with t2dm.It has important clinical significance for the early diagnosis of dpn and the curative effect evaluation.

Journal: Frontiers in neurology (2022)
Publication types: Journal Article
Experiences and perceptions of care-seeking for febrile illness among caregivers, pregnant women, and health providers in eight districts of Madagascar.

Prompt diagnosis and treatment of malaria contributes to reduced morbidity, particularly among children and pregnant women; however, in madagascar, care-seeking for febrile illness is often delayed.To describe factors influencing decisions for prompt care-seeking among caregivers of children aged < 15 years and pregnant women, a mixed-methods assessment was conducted with providers (hp), community health volunteers (chv) and community members.Methods one health district from each of eight malaria-endemic zones of madagascar were purposefully selected based on reported higher malaria transmission.Within districts, one urban and one rural community were randomly selected for participation.In-depth interviews (idi) and focus group discussions (fgd) were conducted with caregivers, pregnant women, chvs and hps in these 16 communities to describe practices and, for hps, system characteristics that support or inhibit care-seeking.Knowledge tests on malaria case management guidelines were administered to hps, and logistics management systems were reviewed.Results participants from eight rural and eight urban communities included 31 hps from 10 public and 8 private health facilities (hf), five chvs, 102 caregivers and 90 pregnant women.All participants in fgds and idis reported that care-seeking for fever is frequently delayed until the ill person does not respond to home treatment or symptoms become more severe.Key care-seeking determinants for caregivers and pregnant women included cost, travel time and distance, and perception that the quality of care in hfs was poor.Hps felt that lack of commodities and heavy workloads hindered their ability to provide quality malaria care services.Malaria commodities were generally more available in public versus private hfs.Chvs were generally not consulted for malaria care and had limited commodities.Conclusions reducing cost and travel time to care and improving the quality of care may increase prompt care-seeking among vulnerable populations experiencing febrile illness.For patients, perceptions and quality of care could be improved with more reliable supplies, extended hf operating hours and staffing, supportive demeanors of hps and seeking care with chvs.For providers, malaria services could be improved by increasing the reliability of supply chains and providing additional staffing.Chvs may be an under-utilized resource for sick children.

Journal: Malaria journal (2022)
Publication types: Journal Article
Pentraxin-3 - a potential biomarker in ANCA-associated vasculitis.

The aim of this study was to investigate pentraxin-3 (ptx3) as a potential biomarker of inflammatory activity in patients with anti-neutrophil cytoplasmic antibody (anca)-associated vasculitis (aav) at baseline and 6 month follow-up in a longitudinal cohort.Method plasma ptx3 levels were measured in 79 newly diagnosed or relapsing aav patients at baseline and 6 month follow-up, and in 23 healthy controls.Urinary ptx3 levels were measured in 34 of the patients.C-reactive protein (crp), creatinine, and albuminuria were measured and the cumulative glucocorticoid dose at inclusion was calculated.The birmingham vasculitis activity score (bvas) was assessed at baseline and follow-up.Results plasma ptx3 levels were significantly higher at baseline than at 6 months (2.85 vs 1.23 ng/m l, p < 0.001).Plasma and urinary ptx3 levels correlated with bvas at baseline (ρ = 0.45, p < 0.001, and ρ = 0.49, p = 0.008, respectively).A significant correlation between both plasma and urinary ptx3 levels and estimated glomerular filtration rate and albuminuria was found.However, there was no correlation between plasma and urinary ptx3 levels.At baseline, plasma and urinary ptx3 levels were significantly higher in patients with kidney involvement.Ptx3 levels did not correlate with crp, nor was there a correlation between crp levels and bvas at baseline.Conclusion plasma and urinary ptx3 seem to reflect disease activity in aav better than the commonly used crp.Ptx3 may have a potential role as a biomarker in monitoring disease activity in aav patients, particularly in patients with kidney involvement.

Journal: Scandinavian journal of rheumatology (2023)
Publication types: Journal Article