syedzayyan/paper_mill_benchmark huggingface dataset:
The Influence of Air Pollution on Pulmonary Disease Incidence Analyzed Based on Grey Correlation Analysis

Air pollution is a primary health threat issue worldwide because it is closely concerned with respiratory diseases.A random survey reported that around 7 million people died because of ambient and household air pollution.Especially, the people suffering from asthma and chronic obstructive pulmonary disease (copd) are highly affected by air pollutants.The air pollution components induce asthma onset and copd acute exacerbation, which leads to maximized mortality and morbidity rate.Therefore, the influence of air pollution on copd should be examined continuously to minimize the mortality rate.Several methods are presented in this field to investigate the relationship between health and pollutants.However, the existing approaches are only predicting the short‐term data and have difficulties such as computation time, redundant data in large data analysis, and data continuity.Then, this research introduced the meta‐heuristic optimized grey correlation analysis (mh‐gca) to solve the research difficulties.The correlation analysis has several models that identify the relationship between the pollution factors with copd disease.The method analysis of the particulate matter (〖pm〗_10) in air pollution is more relevant to copd and lung cancer disease.The grey analysis uses the uncertainty concept to identify the particle influence on air pollution.In the analysis, the cuttlefish optimization algorithm was applied to select more relevant features from the pollutant list that reduces the computation time and correlation analysis rate.The introduced system was evaluated using the air quality dataset and copd dataset developed with the help of the matlab tool.The system increases the influence recognition accuracy (2.48%) and mcc (3.11%) and decreases the error rate (55.89%) for different pollutants.

Journal: Contrast Media & Molecular Imaging (2022)
Publication types: Research Article;
The Importance of Early Identification for Parkinson’s Disease Patients with Postural Instability and Gait Disturbance

More and more evidence-based medicine has proved that parkinson’s disease (pd) patients of tremor-dominant (td) and postural instability and gait difficulty (pigd) subtype express great individual differences and heterogeneity.Early identification of different subtypes may be an important way to delay disease progression and improve patients’ prognosis.Objective.The study aimed to compare the spectrum of motor symptoms (ms) and nonmotor symptoms (nms) between td and pigd dominant in the early and middle stages of pd, and determine predictive factors that are associated with different motor subtypes.Methods.292 pd patients in this study were divided into td-pd and pigd-pd, and the clinical characteristics between different motor subtypes were compared based on scales related to sleep, mood, and autonomic function.Univariate and multivariate ordered logistic regression analyses were used to analyze the independent influencing factors of disease severity between different motor subtypes.Through the establishment of binary logistic regression model, the potential independent risk factors for distinguishing td-pd and pigd-pd were studied.Results.Compared with td subtype, patients with pigd subtype have longer course of disease, higher disease severity, and higher daily dosage of levodopa.The severity of nontremor motor symptoms in pigd-pd is greater than that of td subtype.Only pigd score was independently associated with disease severity for the two motor subtypes.Meanwhile, high scores (led, total updrs, pigd score, gastrointestinal, thermoregulatory, rbdsq) and low tremor scores were the potential independent risk factors for distinguishing pigd-pd from td-pd.Conclusion.Specific nonmotor symptoms (rbd, gastrointestinal function and thermoregulation function) were associated with the pigd subtype.Prompt detection and early treatment of nmss related to the pigd subtype based on the treatment of motor symptoms may improve patient outcomes.

Journal: Computational Intelligence and Neuroscience (2022)
Publication types: Research Article;
The Impact of lncRNA on Diabetic Kidney Disease: Systematic Review and In Silico Analyses

Long noncoding rna (lnc rna) is involved in the occurrence and development of diabetic kidney disease (dkd).It is necessary to identify the expression of lnc rna from dkd patients through systematic reviews, and then carry out silico analyses to recognize the dysregulated lnc rna and their associated pathways.Methods.The study searched pubmed, embase, cochrane library, wan fang, vip, cnki, and cbm to find lnc rna studies on dkd published before march 1, 2021.Systematic review of the literature on this topic was conducted to determine the expression of lnc rna in dkd and non-dkd controls.For the dysregulated lnc rna in dkd patients, silico analysis was performed, and lnc rna2target v2.0 and star base were used to search for potential target genes of lnc rna.The encyclopedia of genomics (kegg) pathway enrichment analysis was performed to better identify dysregulated lnc rnas in dkd and determine the associated signal pathways.Results.According to the inclusion and exclusion criteria, 28 publications meeting the eligibility criteria were included in the systematic evaluation.A total of 3,394 patients were enrolled in this study, including 1,238 patients in dkd group, and 1,223 diabetic patients, and 933 healthy adults in control group.Compared with the control, there were eight lnc rna disorders in dkd patients (malat1, gas5, miat, casc2, neat1, nr_033515, arap1-as2, and arap1-as1).In addition, five lnc rnas (malat1, gas5, miat, casc2, and neat1) participated in disease-related signal pathways, indicating their role in dkd.Discussion.This study showed that there were eight lnc rnas in dkd that were persistently dysregulated, especially five lnc rnas which were closely related to the disease.Although systematic review included 28 studies that analyzed the expression of lnc rna in dkd-related tissues, the potential of these dysregulated lnc rnas as biomarkers or therapeutic targets for dkd remains to be further explored.Trial registration.Prospero (crd42021248634).

Journal: Computational Intelligence and Neuroscience (2022)
Publication types: Review Article;
The Impact of 3S2E Nursing Management on the Psychological Status of Respiratory Function and Quality of Life of Patients with Severe Pneumonia in the ICU

This study examines the effects of the 3s2e nursing management mode on patients with severe pneumonia in the intensive care unit’s respiratory function, psychological status, and quality of life (icu).Methods.According to a random number table, 82 icu patients with severe pneumonia who were admitted between march 2021 and march 2022 were enrolled and assigned to the control and observation class (n = 41, respectively) in a 1 : 1 ratio.The observation class added 3s2e manner in addition to ordinary breastfeeding, whereas the control class received treatment in the usual nursing mode.The two groups’ preintervention and postintervention times for mechanical ventilation, white blood cell count (wbc) recovery, duration of hospital stay, problems, respiratory function, psychological state, and living quality were compared.Results.Fever time abatement, mechanical ventilation time, wbc recovery time, and length of hospital stay in the observation category were found to be shorter in comparison with the control class ( p &lt; 0.05 ).In contrast to the other group, the observation group had fewer issues ( p &lt; 0.05 ).Both teams’ oxygenation indices and sa o2 were higher after the intervention ( p &lt; 0.05 ), with the observation team’s index being higher than the control group’s index.The total sas and sds scores of the two groups were less in the postintervention period than in the preintervention period, with the observational class having lower postintervention sas and sds ratings than the comparison group ( p &lt; 0.05 ).The postintervention ratings in the observation class were higher than those in the control, and the world health organization quality of life (whoqol) scale scores in the 2 categories were greater after the intervention than they were before ( p &lt; 0.05 ).Conclusion.3s2e nursing management model improves respiratory function, alleviates negative emotions, and improves living quality in icu patients with severe pneumonia.

Journal: Emergency Medicine International (2022)
Publication types: Clinical Study;
The High Expression of Adhering and Circulating Integrin Serves as a Diagnostic Marker in Venous Thromboembolism

To investigate the diagnostic value of circulating integrins β1, 2, and 3 in venous thrombosis (vte).Materials and methods.A total of 474 vte patients and 306 patients with nonhigh risk for vte as the control group were studied.Levels of adhering integrins β1, 2, and 3 were detected by flow cytometry.Levels of circulating integrins β1, 2, and 3 in serum were measured by enzyme-linked immunosorbent assay.Results.We found that integrins β1, 2, and 3 were expressed highly both in serum and on the surface of leukocytes and platelets in venous thromboembolism.The levels of circulating integrins β1, 2, and 3 are positively correlated with adhering integrins.It showed excellent clinical diagnostic performance of circulating integrins β1, 2, and 3 in venous thromboembolism.Conclusions.Integrin subunit β can be used as a diagnostic marker with high sensitivity and specificity for venous thromboembolism.

Journal: Computational and Mathematical Methods in Medicine (2022)
Publication types: Research Article;
The Effectiveness and Safety of Hormonal Combinations of Antiepileptic Drugs in the Treatment of Epileptic Electrical Continuity in Children during Sleep: A Meta-Analysis

A systematic evaluation of the efficacy of hormones in combination with antiepileptic drugs (aeds) compared to aeds alone in the treatment of children with encephalopathy related to status epilepticus during slow sleep (eses).This study provides an evidence-based approach to the treatment of children with eses.Materials and methods.To find all relevant studies published before march 2022, we searched pub med, embase, web of science, clinical trials, cochrane library, cnki, and wanfang databases.We explore the difference between aeds combined with hormones and aeds alone for eses treatment.All outcome data, including wechsler intelligence scale for children, the effective rate, eeg discharges, and adverse effects rate (aer), were compared using review manager 5.3.Results.There were 805 patients in this study’s seven investigations, including 403 in the experimental group and 402 in the control group.Meta-analysis showed that after treatment, compared with the aeds alone group, the hormone combined with aeds.The difference in clinical improvement rate [rr = 1.25, 95% ci (1.15, 1.36), p &lt; 0.00001], electroencephalographic (eeg) discharge improvement rate [rr = 1.31, 95% ci (1.22, 1.41), p &lt; 0.00001], and cognitive intelligence score [smd = 1.02, 95% ci (0.76, 1.28), p &lt; 0.00001] was statistically significant.The differences were statistically significant in terms of 0.00001; the incidence of adverse reactions was higher in the hormone combined with aeds group than in the aeds group alone, and the differences were statistically significant [rr = 4.13, 95% ci (1.06, 16.13), p &lt; 0.01], and all adverse reactions improved or disappeared after discontinuation of the drug.Conclusions.The combination of hormones with aeds for the treatment of epileptic electrical continuity in sleep has advantages over aeds alone in terms of controlling seizures, improving eeg abnormalities, and improving cognition.The combination of hormones with aeds has advantages over aeds alone in controlling seizures, improving eeg abnormalities, and improving cognition and is relatively safe.

Journal: Computational Intelligence and Neuroscience (2022)
Publication types: Meta-Analysis;
The Effect of Long-Term External Counterpulsation Combined with Exercise Therapy on the Establishment of Collateral Circulation in Patients with Coronary Artery Occlusive Disease

By detecting the levels of external counterpulsation combined with exercise therapy on the levels of moesin, angiopoietin‐like protein2 (angptl 2), angiopoietin‐like protein (angptl 3), hypoxia inducible factor‐1 α (hif‐1 α ), and rna‐34a (mi r‐34a) in patients with coronary artery occlusive disease, the effect of external counterpulsation combined with exercise therapy on the establishment of occluded coronary collateral circulation was studied.Methods .A retrospective analysis of 166 patients with coronary heart disease was confirmed by coronary angiography results that at least one coronary artery (anterior descending branch, circumflex branch, and right coronary artery) was completely occluded and was classified into the control group (routine medication) and the treatment group (routine drug therapy plus exercise therapy and external counterpulsation) according to the treatment plan of the patient.The serum levels of moesin, angptl 2, angptl 3, and hif‐1 α were detected by enzyme‐linked immunosorbent assay (elisa) test.The index of microcirculatory resistance (imr) and coronary flow reserve (cfr) of the two groups of patients were measured before and after 2 weeks of treatment.The formation of collateral circulation was analyzed according to the rentrop classification method.Results .After treatment, the imr levels of the two groups were significantly decreased, and the cfr levels were significantly increased.The decrease of imr level and the increase of cfr level in the experimental group were better than those in the control group ( p &lt; 0.05).There was no significant difference in the positive detection rate of moesin antibody between the two groups, but the od detection value of the treatment group decreased significantly ( p &lt; 0.05).The levels of angptl 2, angptl 3, and mi r‐34a in the treatment group were lower than those in the control group, while the relative expression of hif‐1 α was higher than that in the control group.The difference was statistically significant ( p &lt; 0.05).External counterpulsation combined with exercise therapy improved the formation rate of collateral circulation ( p &lt; 0.05).Conclusions .External counterpulsation combined with exercise therapy can reduce moesin antibody, angptl 2, angptl 3, and mi r‐34a levels increase hif‐1 α levels, and promote the establishment of occluded coronary collateral circulation.

Journal: BioMed Research International (2022)
Publication types: Research Article;
The Effect of a New Ligation and Venipuncture Method on Vena Basilica Vessel

This study evaluated the impact of a novel venipuncture method on vascular parameters of vena basilica to provide a new technical option for the clinical management of difficult venipuncture.Methods.32 volunteers examined by ultrasound at the medical imaging center of the first people’s hospital of nantong, jiangsu province, from february 2020 to april 2020 were randomly selected.One hand of each patient was ligated with the traditional single tourniquet and the new ligation method for 20 seconds.Then, the distance between the left or right vena basilica and the skin and the diameter of blood vessels were measured by ultrasound.98 patients with peripheral venipuncture difficulty who were examined by ultrasound of a third-grade hospital from april 2019 to march 2020 were selected and randomly divided into control group ( n = 49 ) and experimental group ( n = 49 ).The traditional method was used in the control group, and the new peripheral venipuncture was used in the experimental group.The success rate of single puncture, preparation time before puncture, time required for puncture operation, pain reaction during puncture, intravascular congestion after puncture, subcutaneous tissue injury, and vascular reuse rate after puncture were compared between the two methods.Results.The new ligation and puncture method increased the diameter of peripheral superficial vein vessels by 0.51 ± 0.04 mm , and the change of vena basilica diameter was not significantly associated with gender and age of patient.The success rate of single puncture and the vascular reuse rate were significantly higher in the experimental group than in the control group, while the preparation time and venipuncture time, as well as the patient’s pain response, were significantly lower in the experimental group compared to the control group, and the intravascular congestion and subcutaneous tissue injury were lower.In addition, the mean satisfaction score of patients in the experimental group was higher than that of the control group.Conclusion.The new ligation and puncture method was an effective vena basilica dilation technique for filling the peripheral superficial veins, improving puncture success rate of peripheral difficult vein, and reducing patient pain, which was worth popularizing and applying in clinic.

Journal: Applied Bionics and Biomechanics (2022)
Publication types: Clinical Study;
The Correlation between Type 2 Diabetes Mellitus and Cardiovascular Disease Risk Factors in the Elderly

With the improvement of people’s living conditions and changes in social lifestyles, the incidence of type 2 diabetes is gradually increasing, and the number of people with diabetes and cardiovascular disease is also increasing.Based on this, the article collects basic information on 650 elderly patients with type 2 diabetes, of which 49.39% are between 60 and 70 years old, 32.46% are between 70 and 80 years old, and 18.15% are between 80 and 90 years old.Through the analysis of related cardiovascular disease risk factors, the correlation between the elderly cardiovascular disease risk factors and type 2 diabetes is explored.The results showed that the correlations between smoking history, diastolic blood pressure, total cholesterol, low-density lipoprotein cholesterol, and the risk of type 2 diabetes in the elderly were 0.987, 0.956, 0.971, and 0.940, respectively.It can be seen that these factors are highly correlated with the risk of type 2 diabetes in the elderly, and smoking history has the strongest correlation, indicating that high levels of smoking may be a key pathogenic factor in the onset of type 2 diabetes.The correlation of other factors is lower than 0.8, indicating that other factors are additional risk factors for the disease.After that, the p value was 0.01, and the difference test was passed, which proved the accuracy of the model.

Journal: Applied Bionics and Biomechanics (2022)
Publication types: Research Article;
The Construction of Smart Chinese Medicine Cloud Health Platform Based on Deep Neural Networks

In order to improve the efficiency of doctors’ diagnosis and treatment, the state has built a chinese medicine cloud health platform.However, most medical institutions currently use internal networks, and the technical standards and specifications are not uniform.Some information is not compatible and patient information cannot be shared.Therefore, the construction of a smart traditional chinese medicine (tcm) cloud health platform based on deep neural networks has become a current research hotspot.The research results show that the deep neural network technology has a theoretical basis and feasibility in the smart chinese medicine cloud health platform.Combining with deep neural network technology, a cloud-based chinese medicine cloud health system has been developed through big data analysis technology.Through the investigation and research method, this paper found that the smart chinese medicine cloud health platform based on deep neural networks was more popular with citizens, which could improve the quality and efficiency of management.The average management quality of a smart tcm health cloud platform based on deep neural networks was 81.1, and the average management quality of a common tcm cloud health platform was 75.The efficiency of the smart chinese medicine cloud health platform based on deep neural networks was relatively stable, with an average of 84%.The efficiency of the general tcm cloud health platform fluctuated significantly and was relatively unstable, with an average of 73.5%.The efficiency of the smart chinese medicine cloud health platform was 10.5% higher than that of the ordinary chinese medicine cloud health platform.This shows that the construction of the intelligent chinese medicine cloud health platform under the deep neural network is relatively successful.

Journal: International Transactions on Electrical Energy Systems (2022)
Publication types: Research Article;
The Commitment of Nineveh Governorate Residents to the Precautionary Measures against Global 2019 Pandemic and Dermatological Affection of Precautions

The world has changed dramatically since the novel pandemic pours in all aspects of life, including economic, health, and social life.The first case was initially observed in the wuhan province of china; fast spread occurs around the world.Until now, there is no proven effective treatment for it.The study’s objectives are to assess residents of nineveh governorate’s commitment to the covid-19 pandemic precautionary measures recommended by the who and iraqi national authorities; the protective measures are used to prevent its spread and restrict the viral infectivity.Several cutaneous changes were observed in some persons as a result of prolonged contact with personal protective equipment and excessive use of personal hygiene measures.

Journal: Applied Bionics and Biomechanics (2021)
Publication types: Research Article;
The Balance Reaction Ability of Teenagers Based on the Evaluation Model of Unbalanced Sports Quotient

Dynamic balance is particularly important for the maintenance, transformation, and restabilization of various postures of the human body.Combined with the characteristics of unbalanced sports events, although there is no physical contact in sports events, it has intense antagonism due to the constant change of body movement.Athletes need to have the ability of fast movement and continuous high‐intensity multibeat confrontation.They need to adjust their body posture any time according to the situation, constantly move their body from one side to the other side in fast movement, and constantly change between being imbalanced and being stable to keep the center of gravity stable and adjust their body posture.Combining with the characteristics of unbalanced sports, this paper is aimed at the problem that young athletes have poor dynamic balance ability and cannot maintain the stability of their body’s center of gravity in the process of fast multidirectional movement and braking.The supporting leg needs ankle dorsiflexion, knee flexion, and hip flexion during sebt testing.Therefore, the lower limb needs sufficient range of motion, strength, proprioception, and neuromuscular control ability to achieve the optimal test results.A randomized controlled experiment was used to test whether there were significant differences in the test indicators between the experimental group and the control group before and after the experiment by using a paired test.The test indicators between the experimental group and the control group before and after the intervention were tested by independent sample test to explore the influence of core balance training on the dynamic balance ability of teenagers in unbalanced sports.Through analysis, it is proved that strengthening balance exercise can significantly improve the functional movements and physical fitness of adolescents, which is of great significance to the development of basic flexibility and stability of joints and the strengthening of weak chain muscles.

Journal: BioMed Research International (2022)
Publication types: Clinical Study;