syedzayyan/paper_mill_benchmark huggingface dataset:
Optical Sensing of Fractional Quantum Hall Effect in Graphene.

Graphene and its heterostructures provide a unique and versatile playground for explorations of strongly correlated electronic phases, ranging from unconventional fractional quantum hall (fqh) states in a monolayer system to a plethora of superconducting and insulating states in twisted bilayers.However, the access to those fascinating phases has been thus far entirely restricted to transport techniques, due to the lack of a robust energy bandgap that makes graphene hard to access optically.Here we demonstrate an all-optical, noninvasive spectroscopic tool for probing electronic correlations in graphene using excited rydberg excitons in an adjacent transition metal dichalcogenide monolayer.These excitons are highly susceptible to the compressibility of graphene electrons, allowing us to detect the formation of odd-denominator fqh states at high magnetic fields.Owing to its submicron spatial resolution, the technique we demonstrate circumvents spatial inhomogeneities and paves the way for optical studies of correlated states in optically inactive atomically thin materials.

Journal: Nano letters (2022)
Publication types: Journal Article
Risk factors for microbiologic failure in children with Enterobacter species bacteremia.

Enterobacter species are an important cause of healthcare-associated bloodstream infections (bsi) in children.Up to 19% of adult patients with enterobacter bsi have recurrence of infection resistant to third-generation cephalosporins (3gcs) while on therapy with a 3gc.Data are lacking regarding the incidence of and risk factors for recurrence of infection in children with enterobacter bsi.Methods we conducted a retrospective case-control study of patients aged ≤21 years old admitted to texas children's hospital from january 2012 through december 2018 with enterobacter bsi.The primary outcome was microbiologic failure from 72 hours to 30 days after the initial bsi (cases).The secondary outcome was isolation of a 3gc non-susceptible enterobacter sp.From a patient with an initial 3gc-susceptible isolate.Results twelve patients (6.7%) had microbiologic failure compared to 167 controls without microbiologic failure.Of the 138 patients (77.1%) with an enterobacter sp.Isolate that was initially susceptible to 3gcs, 3 (2.2%) developed a subsequent infection with a non-susceptible isolate.Predictors of microbiologic failure were having an alternative primary site of infection besides bacteremia without a focus or an urinary tract infection (or, 9.64; 95% ci, 1.77-52.31; p < 0.01) and inadequate source control (or, 22.16; 95% ci, 5.26-93.36; p < 0.001).Conclusions source of infection and adequacy of source control are important considerations in preventing microbiologic failure.In-vitro susceptibilities can be used to select an antibiotic regimen for the treatment of enterobacter bsi in children.

Journal: PloS one (2021)
Publication types: Journal Article
High efficacy and economical procedure of oral vaccination against Lactococcus garvieae/Streptococcus iniae in rainbow trout (Oncorhynchus mykiss).

The present study was aimed to examine the efficacy of chitosan-alginate coated vaccines against pathogenicity of lactococcus garvieae and streptococcus iniae in rainbow trout.Fish were divided into four groups including: group a: fish immunized by chitosan-alginate coated vaccine, group b: fish immunized by non-coated vaccine, group c: fish feed by chitosan-alginate coated pellets without vaccine and group d: fish feed by basic diet (non-coated and without vaccine).In groups a and b, the vaccination was carried out for 14 days and after that supplemented with fundamental diet (control diet).Comparable to groups a and b, fish of group c were also fed 14 days with test diets and after that fed control food.On day 0, 20, 40 and 60 of the experiment, serum samples were given.Fish have been challenged with live l.Garvieae and s.Iniae after 60 days.The levels of bactericidal activity and complement activity among innate immunity components extended on day 20 of the research and after that decreased in group a and b (p 0.05).In group a, the serum antibody titer against l.Garvieae and s.Iniae broadly raised on day 40 and 60 of examination, whereas in group b, the immune response titer against s.Iniae and l.Garvieae illustrated a significant elevation on day 60 of the trial (p < 0.05).After challenge with live bacteria, survival rate of 83 ± 9.1%(challenged with s.Iniae) and 72.18 ± 9.8% (challenged with l.Garvieae) were gotten independently in group a, which were higher than survival of other exploratory groups (p < 0.05).In conclusion, the results of the present examination appear that the orally vaccination of rainbow trout with chitosan-alginate covered vaccine stimulates immunity system and also efficiently protects rainbow trout against lactococcus garvieae and streptococcus iniae.

Journal: Fish & shellfish immunology (2020)
Publication types: Journal Article
Porous organic polymers for CO2capture, separation and conversion.

Porous organic polymers (pops) have long been considered as prime candidates for carbon dioxide (co2) capture, separation, and conversion.Especially their permanent porosity, structural tunability, stability and relatively low cost are key factors in such considerations.Whereas heteratom-rich microporous networks as well as their amine impregnation/functionalization have been actively exploited to boost the co2affinity of pops, recently, the focus has shifted to engineering the pore environment, resulting in a new generation of highly microporous pops rich in heteroatoms and featuring abundant catalytic sites for the capture and conversion of co2into value-added products.In this review, we aim to provide key insights into structure-property relationships governing the separation, capture and conversion of co2using pops and highlight recent advances in the field.

Journal: Chemical Society reviews (2022)
Publication types: Journal Article;Review
Neonatal bilateral adrenal hemorrhage and adrenal insufficiency accompanied by Subgaleal hematoma: a case report with brief review of literature.

Neonatal adrenal hemorrhage (nah) is an almost infrequent phenomenon (0.2-0.55%).Mechanical compression and alterations of venous pressure during delivery are considered the most probable explanations.Approximately 10% of the cases might have bilateral involvement.Clinical symptoms include abdominal mass, poor feeding, vomiting, prolonged jaundice, and anemia.Subgaleal hemorrhage (sgh) is one of the most clinically remarkable and potentially hazardous postnatal cranial injuries.Case presentation an early-term iranian male neonate who was born through spontaneous vaginal delivery and experienced shoulder dystocia was diagnosed with bilateral nah leading to adrenal insufficiency requiring glucocorticoid and mineralocorticoid supplementation.The sgh and jaundice were other postnatal complications.Serial monthly abdominal and brain ultrasound revealed complete regression of lesions after 70 days.However, after 16 months, the neonate has been still treated with hydrocortisone and fludrocortisone for the adrenal insufficiency diagnosis.He has a lower limit weight for age; however, developmental milestones have been appropriate for age.Discussion and conclusion adrenal hemorrhage and sgh should be examined and looked for, particularly with proven evidence of difficult delivery and asphyxia in at-risk newborns.Clinical and ultrasound follow-up is mandatory for the assessment of hemorrhage resolution and conservative management.The early detection and treatment of adrenal insufficiency by laboratory examination is strongly recommended in bilateral cases.Furthermore, the early recognition of postnatal sgh to prevent clinical and neurological outcomes seems essential.

Journal: BMC pediatrics (2022)
Publication types: Case Reports;Journal Article;Review
Digital twins to enable better precision and personalized dementia care.

In this perspective paper, we want to highlight the potential benefits of incorporating digital twins to support better dementia care.In particular, we assert that, by doing so, it is possible to ensure greater precision regarding dementia care while simultaneously enhancing personalization.Digital twins have been used successfully in manufacturing to enable better prediction and tailoring of solutions to meet required needs, and thereby have enabled more effective and efficient deployment of resources.We develop a model for digital twin in the healthcare domain as a clinical decision support tool by extrapolating its current uses from the manufacturing domain.We illustrate the power of the developed model in the context of dementia.Given the rapid rise of chronic conditions and the pressures on healthcare delivery to provide high quality, cost-effective care anywhere and anytime, we assert that such an approach is consistent with a value-based healthcare philosophy and thus important as the numbers of people with dementia continues to grow exponentially and this pressing healthcare issue is yet to be optimally addressed.Further research and development in this rapidly evolving domain is a strategic priority for ensuring the delivery of superior dementia care.

Journal: JAMIA open (2022)
Publication types: Journal Article;Review
Revealing Ultrafast Energy Dissipation Pathway of Nanocrystalline Sunscreens Oxybenzone and Dioxybenzone.

Two widely used ultraviolet filters, oxybenzone and dioxybenzone, are applied in a variety of areas, particularly in sunscreen cosmetics.Ultrafast femtosecond transient absorption is utilized to trace the excited states and transient states of the nanocrystalline suspension and solution phase of these two molecules.The analysis reveals the intriguing discovery that the transient species of the oxybenzone nanocrystalline suspension have shorter lifetimes than that in solution.The energy dissipation mechanism of these molecules is simulated by density functional theory calculations, and the potential energy surface calculations and the single-crystal structure can well explain the fast decay dynamics of the nanocrystalline transient states of these two molecules.

Journal: The journal of physical chemistry letters (2019)
Publication types: Journal Article
Genome Resource ofAncylobacter pratisalsiE130T: A Novel Plant-Growth-Promoting Bacterium Isolated from the Rhizosphere.

Ancylobacter pratisalsisp.Nov.Strain e130tis a gram-negative, nonmotile, aerobic, and rod-shaped bacterium that was recently isolated from the rhizosphere of plantago winteri wirtg.From a natural salt meadow.This strain was described as novel species in genus ancylobacter; however, information about its complete genome has yet not been reported.In this study, its genome was completely sequenced by pac bio smrt cell platform, analyzed, and compared with other selected complete genome sequences of ancylobacterto elucidate its potential plant growth promotion abilities.The genomic analysis revealed that the genome of strain e130tconsists of one circular dna chromosome of 4,618,530 bp with a gc content of 66% and one plasmid of 159,741 bp with a gc content of 64.13%.The entire genome contains 4,322 predicted coding genes, 49 transfer rnas, and 6 ribosomal rna genes.Genome analysis identified a siderophore natural product biosynthesis cluster, which produces fuscachelin.Knockout of several key genes in this cluster significantly reduces the plant-growth-promotion ability of the strain e130t.In addition to plant-growth promotion, the strain e130tcan grow well on 5% na cl (wt/vol), indicating that this strain is a potential bioresource for successful production of economic crops in alkaline soil.

Journal: Phytopathology (2022)
Publication types: Journal Article
The Influence of Vicarious Fear-Learning in "Infecting" Reactive Action Inhibition.

Since the dawn of cognitive neuroscience, emotions have been recognized to impact on several executive processes, such as action inhibition.However, the complex interplay between emotional stimuli and action control is not yet fully understood.One way to measure inhibitory control is the stop-signal task (sst), which estimates the ability to cancel outright an action to the presentation of a stop signal by means of the stop-signal reaction times (ssrts).Impaired as well as facilitated action control has been found when faced with intrinsic emotional stimuli as stop signals in ssts.Here, we aimed at investigating more deeply the power of negative stimuli to influence our action control, testing the hypothesis that a previously neutral stimulus [i.e., the image of the severe acute respiratory syndrome coronavirus 2 (sars-co v-2)], which has been conditioned through vicarious fear learning, has the same impact on reactive action inhibition performance as an intrinsically negative stimulus (i.e., a fearful face or body).Action control capabilities were tested in 90 participants by means of a sst, in which the stop signals were represented by different negative stimuli.Results showed that the sars-co v-2 image enhanced the ability to suppress an ongoing action similarly to observing fearful facial expressions or fearful body postures.Interestingly, we found that this effect was predicted by impulsivity traits: for example, the less self-control the participants had, the less they showed emotional facilitation for inhibitory performance.These results demonstrated that vicarious fear learning has a critical impact on cognitive abilities, making a neutral image as threatening as phylogenetically innate negative stimuli and able to impact on our behavioral control.

Journal: Frontiers in behavioral neuroscience (2022)
Publication types: Journal Article
Favorable impact of non-alcoholic fatty liver disease on the cerebral white matter hyperintensity in a neurologically healthy population.

And purpose although non-alcoholic fatty liver disease (nafld) shares common cardiovascular risk factors with cerebral white matter hyperintensity (wmh), few studies have reported the association between nafld and wmh.The association between the presence of nafld with its severity and the volume of wmh was investigated.Methods this cross-sectional study was conducted for 2460 subjects who voluntarily participated in health screening check-ups including brain magnetic resonance imaging and liver ultrasonography at the health promotion center at seoul national university hospital from 2009 to 2013.Ultrasonography was used to detect the presence and severity of nafld combined with the nafld fibrosis score and the fib-4 index.The volume of wmh was measured using a semi-automated quantification method by a trained neurologist.Results the prevalence of nafld was 36.5%, and the median volume of wmh in all the subjects was 1.1 ml (interquartile range 0.2-2.7 ml).The presence of nafld was associated with a smaller volume of wmh [β (standard error, se) -0.051 (0.046); p = 0.012].Moderate to severe nafld was associated with a smaller volume of wmh than was non-nafld [β (se) -0.067 (0.061); p = 0.002].The negative correlation observed between nafld severity and wmh volume was persistent only in those with low fib-4 index and low nafld fibrosis scores, whereas there was a positive association in those with high fib-4 index and nafld fibrosis scores.Conclusions non-alcoholic fatty liver disease, and its severity, showed a favorable association with wmh volume.However, its causality and mechanism should be evaluated in further relevantly designed studies.

Journal: European journal of neurology (2019)
Publication types: Journal Article;Research Support, Non-U.S. Gov't
Conceptualising 'Undue Influence' in Decision-Making Support for People with Mental Disabilities.

A crucial question in relation to support designed to enable the legal capacity of people with mental disabilities concerns when support constitutes undue influence.This article addresses this question in order to facilitate the development of law and policy in england and wales, by providing a normative analysis of the different approaches to undue influence across decisions about property, contracts, health, finances, and accommodation.These are all potential contexts for supporting legal capacity, and, in doing so, the article compares approaches to undue influence that are rarely considered together.Drawing on the un convention on the rights of persons with disabilities, third sector and public body documents, and law in england and wales, the analysis identifies six models that conceptualise undue influence in terms of: modes of influence; an overborne will; an inference from the situation; an overborne will understood as a mental incapacity; an overborne will in connection with vulnerability; and impaired discursive control.This final approach is a novel proposal for understanding undue influence.The analysis highlights key policy-relevant issues that distinguish the models, and generates a deliberative framework for navigating them, with the 'overborne will', 'inference-based', and 'discursive control' models identified as potentially fitting for the support context.

Journal: Medical law review (2021)
Publication types: Journal Article
Trace CO2capture by an ultramicroporous physisorbent with low water affinity.

Co2accumulation in confined spaces represents an increasing environmental and health problem.Trace co2capture remains an unmet challenge because human health risks can occur at 1000 parts per million (ppm), a level that challenges current generations of chemisorbents (high energy footprint and slow kinetics) and physisorbents (poor selectivity for co2, especially versus water vapor, and/or poor hydrolytic stability).Here, dynamic breakthrough gas experiments conducted upon the ultramicroporous material sifsix-18-ni-β reveal trace (1000 to 10,000 ppm) co2removal from humid air.We attribute the performance of sifsix-18-ni-β to two factors that are usually mutually exclusive: a new type of strong co2binding site and hydrophobicity similar to zif-8.Sifsix-18-ni-β also offers fast sorption kinetics to enable selective capture of co2over both n2(scn) and h2o (scw), making it prototypal for a previously unknown class of physisorbents that exhibit effective trace co2capture under both dry and humid conditions.

Journal: Science advances (2019)
Publication types: Journal Article;Research Support, Non-U.S. Gov't;Research Support, U.S. Gov't, Non-P.H.S.
How should radiation be done for inflammatory breast cancer patients?-a narrative review of modern literature.

This review highlights the considerations of the radiation oncologist when managing patients with inflammatory breast cancer (ibc) as well as the radiation oncologist's role as a member of the multi-disciplinary team.Background ibc makes up only 1-4% of all breast cancer diagnoses but incidence is increasing.Ibc is diagnosed based on a constellation of clinical features, including the rapid onset of breast erythema and edema (peau d'orange) of one-third or more of the skin of the breast and with a palpable border to the edema.Most published ibc local-regional control rates are consistently lower than those observed in non-ibc, which the highlights the need for deliberate treatment techniques to maximize clinical outcomes.Methods for this narrative review, we discuss the principles of radiation target delineation and dose escalation; highlight new findings in the local-regional management of ibc; provide a critical evaluation of the recent literature evaluating local-regional treatment of ibc; and offer a brief introduction to possible future directions regarding the optimal treatment and management of ibc based on our institutional experience.Conclusions ibc is an aggressive type of breast cancer that warrants multi-disciplinary care from breast surgical, medical, and radiation oncology.Several strategies exist to enhance the effect of radiation therapy (rt) on local-regional control, including hyperfractionation, use of bolus, increased total rt dose, and radiosensitizers, which are currently being tested in randomized trials.With an individualized patient approach, local-regional control rates are improving for ibc.

Journal: Chinese clinical oncology (2021)
Publication types: Journal Article;Review
Post kala-azar dermal leishmaniasis in the Indian sub-continent: challenges and strategies for elimination.

Visceral leishmaniasis (vl) is a severe and often fatal form of leishmaniasis caused by leishmania donovaniin the indian sub-continent.Post kala-azar dermal leishmaniasis (pkdl) is a late cutaneous manifestation of vl, typically occurring after apparent cure of vl, but sometimes even without a prior history of vl in india.Pkdl serves as a significant yet neglected reservoir of infection and plays a crucial role in the transmission of the disease, posing a serious threat to the vl elimination program in the indian sub-continent.Therefore, the eradication of pkdl should be a priority within the current vl elimination program aimed at achieving a goal of less than 1 case per 10,000 in the population at the district or sub-district levels of vl endemic areas.To accomplish this, a comprehensive understanding of the pathogenesis of pkdl is essential, as well as developing strategies for disease management.This review provides an overview of the current status of diagnosis and treatment options for pkdl, highlighting our current knowledge of the immune responses underlying disease development and progression.Additionally, the review discusses the impact of pkdl on elimination programs and propose strategies to overcome this challenge and achieve the goal of elimination.By addressing the diagnostic and therapeutic gaps, optimizing surveillance and control measures, and implementing effective intervention strategies, it is possible to mitigate the burden of pkdl and facilitate the successful elimination of vl in the indian sub-continent.

Journal: Frontiers in immunology (2023)
Publication types: Journal Article;Review;Research Support, Non-U.S. Gov't
Metronidazole-Induced Encephalopathy in a 16-Year-Old Girl with Crohn's Disease: Case Report and Review of the Pediatric Literature.

Metronidazole-induced encephalopathy (mie) is a rare and unpredictable complication that is most commonly reported in adults.Here, we present the case of mie in a patient treated with rectal, oral, and intravenous metronidazole.This is the first case of mie reported after suppositories.A 16-year-old girl with crohn's disease treated with mesalazine and exclusive enteral nutrition was operated on due to perianal fistulas and abscesses.She received oral metronidazole for 25 days and rectal metronidazole for 15 days as an adjuvant before surgery.Moreover, 2.5 g of intravenous metronidazole was administrated during the perioperative period.The second day after the surgery, symptoms of cerebellar syndrome appeared.She presented with an inability to coordinate balance and gait.Although she showed accurate verbal responses, her speech was slow, slurred, and scanning.The finger-nose test was positive.The t2-weighted magnetic resonance imaging revealed an increased symmetrical signal within the dentate nuclei of the cerebellum and in the corpus callosum.The changes were characterized by restricted diffusion.Based on the clinical picture and magnetic resonance imaging findings, mie was diagnosed.Treatment with metronidazole was discontinued.The cumulative dose of metronidazole that she received for 29 days was 54 g: 38 g p.o., 13.5 g p.r., and 2.5 g i,v.The first symptoms appeared on the 28th day of antibiotic therapy after receiving 52 g of metronidazole.The neurological symptoms resolved after six days; however, three days after the resolution, paresthesia appeared in the distal phalanges of both feet and lasted for approximately two months.Our report highlights that neurologic symptoms related to metronidazole treatment should raise the suspicion of mie.

Journal: Children (Basel, Switzerland) (2022)
Publication types: Case Reports;Journal Article