syedzayyan/paper_mill_benchmark huggingface dataset:
Analysis of fractured dental implant body from five different implant systems: a long-term retrospective study.

The aim of this study was to perform an analysis of the incidence of implant body fracture and to identify possible risk factors.A long-term follow-up retrospective evaluation of 3477 patients who received 8588 implants from five implant systems was performed.Overall, 2810 patients who received 7502 implants, with an average follow-up of 6.9 years, were included in the analysis.The overall body fracture rate was 0.49% (37/7502), among which 32.4% (12/37) were implants with a reduced diameter.The estimated cumulative fracture rate was 1.24%.Fractures were observed in two patients with three brånemark implants, 13 patients with 15 nobel replace implants, eight patients with eight camlog implants, eight patients with 11 ankylos implants, and none of the patients with thommen implants.Most fractures occurred in the molar region (29/37) and in single implant-supported restorations (30/37).The results showed significant differences between splinted and unsplinted restorations (p = 0.005) and between regular and narrow diameter implants (p = 0.009).Within the limitations of this retrospective analysis, a narrow implant diameter is a potential risk factor for implant body fracture in the posterior region.Furthermore, unsplinted restorations appear to be associated with a higher rate of implant fracture.

Journal: International journal of oral and maxillofacial surgery (2022)
Publication types: Journal Article
AWANet: Attentive-Aware Wide-Kernels Asymmetrical Network with Blended Contour Information for Salient Object Detection.

Although deep learning-based techniques for salient object detection have considerably improved over recent years, estimated saliency maps still exhibit imprecise predictions owing to the internal complexity and indefinite boundaries of salient objects of varying sizes.Existing methods emphasize the design of an exemplary structure to integrate multi-level features by employing multi-scale features and attention modules to filter salient regions from cluttered scenarios.We propose a saliency detection network based on three novel contributions.First, we use a dense feature extraction unit (dfeu) by introducing large kernels of asymmetric and grouped-wise convolutions with channel reshuffling.The dfeu extracts semantically enriched features with large receptive fields and reduces the gridding problem and parameter sizes for subsequent operations.Second, we suggest a cross-feature integration unit (cfiu) that extracts semantically enriched features from their high resolutions using dense short connections and sub-samples the integrated information into different attentional branches based on the inputs received for each stage of the backbone.The embedded independent attentional branches can observe the importance of the sub-regions for a salient object.With the constraint-wise growth of the sub-attentional branches at various stages, the cfiu can efficiently avoid global and local feature dilution effects by extracting semantically enriched features via dense short-connections from high and low levels.Finally, a contour-aware saliency refinement unit (csru) was devised by blending the contour and contextual features in a progressive dense connected fashion to assist the model toward obtaining more accurate saliency maps with precise boundaries in complex and perplexing scenarios.Our proposed model was analyzed with res net-50 and vgg-16 and outperforms most contemporary techniques with fewer parameters.

Journal: Sensors (Basel, Switzerland) (2022)
Publication types: Journal Article
Effects of Diosmin on Vascular Leakage and Inflammation in a Mouse Model of Venous Obstruction.

At present, iliac vein compression syndrome (ivcs) plagues countless people, posing a significant economic and social burden.The progress of current ivcs-related research is slow owing to the limitations of animal models.In this study, we generated a mouse model of iliac vein stenosis (ivs) to monitor the effects of ivcs on venous function, such as increased vascular leakage, the expression of adhesion molecules, and elevated inflammation factors.Diosmin, a widely used clinical bioactive ingredient, was administered to confirm its therapeutic effects on the ivs mouse model.The results revealed that diosmin manifested therapeutic improvement in the ivs mouse model.In addition, we verified that the ivs mouse model is a stable and reproducible animal model for pathophysiological studies.High-purity diosmin can be beneficial to venous dysfunction and hence provides a more effective treatment option for venous diseases.

Journal: Frontiers in nutrition (2022)
Publication types: Journal Article
Socio-economic disparity in food consumption among young children in eight South Asian and Southeast Asian countries.

/objectives this study examined socio-economic differences in diverse food consumption among children 6-23 months of age in south asia and southeast asian countries.Subjects/methods data from demographic and health surveys in four countries in south asia (n = 15,749) and four countries in southeast asia (n = 10,789) were used.Survey-design adjusted proportions were estimated for the following 10 food items: grains, legumes, dark green leafy vegetables (dglv), vitamin a-rich fruits, vitamin a-rich vegetables, other fruits and vegetables (ofv), fish, meat, dairy, and eggs.An equity gap was defined as an arithmetic difference in the proportion of each food item consumed in the past 24-hours between the wealthiest and lowest quintiles and between rural and urban areas, denoted by percentage points (pp).Results the consumption of most of the 10 food items was higher in the wealthiest quintiles and urban areas across eight countries.The size of equity gaps was greater in southeast asia than in south asia, particularly for vitamin a-rich fruits (3.3-30.0 pp vs.0.3-19.6 pp), vitamin a-rich vegetables (12.1-26.7 pp vs.2.4-5.9 pp), meat (17.7-33.4 pp vs.3.4-13.4 pp), and dairy (14.7-32.5 pp vs.3.3-11.4 pp).However, the size of equity gap in egg consumption was greater in southeast asia than south asia (11.2-19.8 pp vs.11.0-26.7 pp).Relatively narrower gaps were seen in the consumption of grains (0.3-12.9 pp), dglv (0.6-12.4 pp), and fish (0.1-16.8 pp) across all countries.Conclusions equity gaps in food consumption differed by socio-economic status and region.Reducing equity gaps in nutrient-rich foods and utilizing regionally available food resources may increase child dietary quality.

Journal: Nutrition research and practice (2022)
Publication types: Journal Article
Post Renal Transplant Collapsing Glomerulopathy is Associated with Poor Outcomes.

Introduction collapsing glomerulopathy (cg) is a distinct morphologic pattern of proliferative renal parenchymal injury.It differ from focal segmental glomerulosclerosis (fsgs) by clinicopathologic pattern and its adverse outcome.The clinical significance of cg in renal allograft biopsies is not yet clear due to scant data and less occurrence of cg in renal transplant recipients.We conducted this single-center retrospective study to evaluate the prevalence, clinicopathological features, and outcome of post renal transplant cg.Subjects and methods we studied 127 renal allograft biopsies performed over a period of 45 months (jan 2015-oct 2018).A diagnosis of cg was made if at least one glomerulus demonstrated global or segmental collapse of the glomerular capillary walls, associated marked hyperplasia, and hypertrophy of the overlying visceral epithelial cells.We analyzed clinical, biochemical, and pathological characteristics and its impact on renal allograft outcome.Statistical analysis was performed and continuous variables were expressed as means ± standard deviation (sd) or medians (interquartile range and noncontinuous data were expressed in percentage and numerical values.Results the prevalence of cg was 5.3% (7/127) of allograft biopsies.Out of the seven patients, six patients had undergone live donor transplant and one patient had undergone deceased donor renal transplant.The native kidney disease was unknown in these patients except one (ig a nephropathy).The median duration of diagnosis for cg was 17 months after transplantation (range 5-132months).Presenting symptoms were pedal edema and hypertension in 71.4% (5) patients each.All patients had proteinuria of more than 1 gm and renal allograft dysfunction and median serum creatinine of 3.05 mg/dl (1.5-4.8 mg/dl).All patients received standard triple immunosuppression.Over a period of 2-20 months, 57.14% (4) patients developed a graft failure and 43% (3) of the other patients had functioning grafts with serum creatinine of 1.5-4.2 mg/dl.Conclusions cg presents with moderate to severe proteinuria and may lead to rapid graft dysfunction and subsequent graft failure in most of the patients.

Journal: Indian journal of nephrology (2020)
Publication types: Journal Article
Re-evaluation of solutions to the problem of unprofessionalism in peer review.

Our recent paper ( ) reported that 43% of reviewer comment sets (n=1491) shared with authors contained at least one unprofessional comment or an incomplete, inaccurate of unsubstantiated critique (iiuc).Publication of this work sparked an online (i.e., twitter, instagram, facebook, and reddit) conversation surrounding professionalism in peer review.We collected and analyzed these social media comments as they offered real-time responses to our work and provided insight into the views held by commenters and potential peer-reviewers that would be difficult to quantify using existing empirical tools (96 comments from july 24th to september 3rd, 2020).Overall, 75% of comments were positive, of which 59% were supportive and 16% shared similar personal experiences.However, a subset of negative comments emerged (22% of comments were negative and 6% were an unsubstantiated critique of the methodology), that provided potential insight into the reasons underlying unprofessional comments were made during the peer-review process.These comments were classified into three main themes: (1) forced niceness will adversely impact the peer-review process and allow for publication of poor-quality science (5% of online comments); (2) dismissing comments as not offensive to another person because they were not deemed personally offensive to the reader (6%); and (3) authors brought unprofessional comments upon themselves as they submitted substandard work (5%).Here, we argue against these themes as justifications for directing unprofessional comments towards authors during the peer review process.We argue that it is possible to be both critical and professional, and that no author deserves to be the recipient of demeaning ad hominem attacks regardless of supposed provocation.Suggesting otherwise only serves to propagate a toxic culture within peer review.While we previously postulated that establishing a peer-reviewer code of conduct could help improve the peer-review system, we now posit that priority should be given to repairing the negative cultural zeitgeist that exists in peer-review.

Journal: Research integrity and peer review (2021)
Publication types: Journal Article
Dreams and nightmares in healthy adults and in patients with sleep and neurological disorders.

Dreams are experiences that occur during sleep, while we are disconnected from the environment.Thanks to recent progress in neuroimaging techniques, it is now becoming possible to relate dream features to specific patterns of brain activity.Some conditions occurring in patients with neurological disorders, such as lucid dreams and parasomnias, not only have diagnostic value, but also offer a window into the dream process.They show that dreaming is reflected in physiological signals, behaviours, and brain activity patterns, and that the body can enact dream content.Yet, the dream body can also be distinct from the real body; in their dreams, patients with congenital paraplegia can walk, those with sleep apnoea rarely suffocate, and phantom limb pain can disappear.These conditions provide valuable models for future studies investigating the mechanisms that underlie oneiric experiences.

Journal: The Lancet. Neurology (2020)
Publication types: Journal Article;Review
Role of malaria partners in malaria elimination in Armenia.

Malaria control and preventive activities in the countries of the world health organization region for europe (who/eur) were strengthened within the framework of the regional roll back malaria strategy adopted by the member-states at the beginning of the 2000s.A political document "from control to malaria elimination" known as the "tashkent declaration" was unanimously endorsed by the member-states of the who/eur with malaria problems in 2005.Since then, considerable progress has been achieved in the countries of the region, signified by the dramatic reduction of malaria incidence in conjunction with the prevention of re-establishment of infection on the territories where malaria was eliminated earlier.Several countries of the region had been certified by the who as free of local malaria transmission as a result of the activities of their national malaria elimination programme, armenia being one of the first in 2011.One of the main lessons learnt during the implementation of the activities by the national malaria elimination programme in armenia was that the development of an operational plan for malaria elimination required a comprehensive national effort.Full support, both political and financial, from the highest levels of government to smooth coordination between different government ministries, such as agriculture, defense, finance, health and policy and planning and others, was a prerequisite for operational success.The role and place of various partners in the achievement of malaria elimination in the country is discussed in this review.

Journal: Malaria journal (2019)
Publication types: Journal Article
How Do Patients With Predominant Neck Pain Improve After Anterior Cervical Discectomy and Fusion for Cervical Radiculopathy?

The presence of predominant pain in the arm vs the neck as a predictor of postoperative outcomes after anterior cervical discectomy and fusion (acdf) has been seldom reported; therefore, the purpose of this study was to determine whether patients with predominant neck pain improve after surgery compared to patients with predominant arm pain or those with mixed symptoms in patients undergoing acdf for radiculopathy.Methods a retrospective cohort study was conducted on patients who underwent acdf at a single center from 2016 to 2018.Patients were split into groups based on preoperative neck and arm pain scores: neck (n) pain dominant group (visual analog scale [vas] neck ≥ vas arm by 1.0 point); neutral group (vas neck 1.0.Patient-reported outcome measurements including neck disability index (ndi), physical component score-12, and mental component score (mcs-12) were compared between groups.Results no significant differences between groups when stratifying patients using a threshold difference of 1.0 point.When stratifying patients using the anr, those in the apd group had significantly higher postoperative mcs-12 (p= 0.008) and ndi (p= 0.011) scores.In addition, the apd group showed a greater magnitude of improvement for mcs-12 and ndi scores (p= 0.043 and p= 0.038, respectively).Multiple linear regression showed that the a and the apd groups were both independent predictors of improvement in ndi.Conclusion patients with dominant arm pain showed significantly greater improvement in terms of mcs-12 and ndi scores compared to patients with dominant neck pain.Clinical relevance to compare the impact of acdf on arm and neck pain in the context of cervical radiculopathy using patient-reported outcome measures as an objective measurement.Level of evidence: 3

Journal: International journal of spine surgery (2022)
Publication types: Journal Article
Transthoracic Migration of a Foreign Body into the Diaphragm from the Gunshot Injury and Its Management in a Child: A Case Report.

Intrapleural foreign bodies (fb) are rare and uncommon, while diaphragmatic fb secondary to gunshot injury in a child is still rarer.We now describe a 9-year-old male with a history of self-inflicted accidental air gun injury on the right side of the midline of the sternum with transthoracic migration of fb-lead bullet-measuring 1cm x1.4cm into the diaphragm managed initially with intercostal tube drainage for right hemopneumothorax at the different center underwent thoracoscopy followed by minithoracotomy and retrieval under c-arm guidance that has not been reported in the literature.

Journal: Surgery journal (New York, N.Y.) (2022)
Publication types: Case Reports;Journal Article
Clearly Detectable, Kinetically Restricted Solid-Solid Phase Transition in cis-Ceramide Monolayers.

Sphingosine [(2 s,3 r,4 e)-2-amino-4-octadecene-1,3-diol] is the most common sphingoid base in mammals.Ceramides are n-acyl sphingosines.Numerous small variations on this canonical structure are known, including the 1-deoxy, the 4,5-dihydro, and many others.However, whenever there is a δ4 double bond, it adopts the trans (or e) configuration.We synthesized a ceramide containing 4 z-sphingosine and palmitic acid ( cis-p cer) and studied its behavior in the form of monolayers extended on an air-water interface.Cis-p cer acted very differently from the trans isomer in that, upon lateral compression of the monolayer, a solid-solid transition was clearly observed at a mean molecular area ≤44 å2·molecule-1, whose characteristics depended on the rate of compression.The solid-solid transition, as well as states of domain coexistence, could be imaged by atomic force microscopy and by brewster-angle microscopy.Atomistic molecular dynamics simulations provided results compatible with the experimentally observed differences between the cis and trans isomers.The data can help in the exploration of other solid-solid transitions in lipids, both in vitro and in vivo, that have gone up to now undetected because of their less obvious change in surface properties along the transition, as compared to cis-p cer.

Journal: Langmuir : the ACS journal of surfaces and colloids (2018)
Publication types: Journal Article;Research Support, Non-U.S. Gov't
A Very Rare Localization of Rhinolith: Fossa of Rosenmuller.

Sixty-five-year old male patient applied to our clinic with nonspecific complaints such as tinnitus, otalgia, headache, halitosis, and persistent globus pharyngeus which had been continued for 5 years.His complaints persisted despite different extensive treatments.In nasoendoscopy, a yellow-colored mass with purulent discharge around was observed in eustachian tube opening in left fossa of rosenmüller.Computed tomography scan showed a mass of 6 × 6 mm size in left fossa of rosenmüller.After excision of the mass under local anesthesia, significant reductions were observed in patient's symptoms.Histopathology of the mass was reported as rhinolith.Although fossa of rosenmüller is a quite rare localization for rhinoliths, it needs to be considered in differential diagnosis of patients with nonspecific symptoms such as halitosis, globus pharyngeus, and otalgia.This report represents a patient with rhinolith localized in fossa of rosenmüller as the 2nd report in the literature.

Journal: The Journal of craniofacial surgery (2020)
Publication types: Case Reports;Journal Article
Liquid crystal-based sensing platform for detection of Pb2+assisted by DNAzyme and rolling circle amplification.

Lead ions (pb2+) are one of the most widespread heavy metal contaminants that pose detrimental impact on environment and human health.We demonstrate a highly sensitive and specific liquid crystal (lc)-based sensing platform for detecting pb2+assisted by dnazyme and rolling circle amplification (rca).Magnetic beads (mbs) are functionalized with dna duplexes of the catalytic strands (dnazymes) and the substrate strands.In the presence of pb2+, the substrate strands are disassembled due to activation of the dnazyme, which allows initiation of dna rca on mbs.The amplified dna strands can disrupt arrangement of octadecy trimethyl ammonium bromide monolayers (otab), thereby inducing planar orientation of lc molecules at the interface of aqueous and lcs.Thus, lcs exhibit bright appearance.In contrast, rca cannot be triggered in the absence of pb2+.Therefore, lc molecules adopt perpendicular orientation at the interface, which induces the dark morphology of lcs.The limit of detection reaches as low as 16.7 p m.It is an improvement of more than two orders of magnitude compared to that of previously reported lc-based sensing approaches.This approach also shows excellent performance in monitoring pb2+in tap water and lake water.

Journal: Journal of hazardous materials (2020)
Publication types: Journal Article;Research Support, Non-U.S. Gov't
Identifying the Critical Anion-Cation Coordination to Regulate the Electric Double Layer for an Efficient Lithium-Metal Anode Interface.

The persistent efforts to reveal the formation and evolution mechanisms of solid electrolyte interphase (sei) are of fundamental significance for the rational regulation.In this work, through combined theoretical and experimental model investigations, we elucidate that the electric double layer (edl) chemistry at the electrode/electrolyte interface beyond the thermodynamic stability of electrolyte components predominately controls the competitive reduction reactions during sei construction on li metal anode.Specifically, the negatively-charged surface of li metal will prompt substantial cation enrichment and anion deficiency within the edl.Necessarily, only the species participating in the solvation shell of cations could be electrostatically accumulated in proximity of li metal surface and thereafter be preferentially reduced during sustained dynamic cycling.Incorporating multi-valent cation additives to more effectively drag the favorable anionic sei enablers into edl is validated as a promising strategy to upgrade the li protection performance.The conclusions drawn herein afford deeper understandings to bridge the edl principle, cation solvation, and sei formation, shedding fresh light on the targeted regulation of reactive alkali metal interfaces.

Journal: Angewandte Chemie (International ed. in English) (2021)
Publication types: Journal Article