syedzayyan/paper_mill_benchmark huggingface dataset:
A Meta-Analysis to Detect Efficacy of Physical Activity Interventions to Enhance Effects Related to the Fragility among Older Adults

The role of physical activity is well-known to intercept the condition of fragility and decrease its outcomes.This study aimed to determine the efficacious physical activity intervention measure which enhances the outcomes associated to fragility in the older adults.Material and methods.We searched medline, cochrane central register of controlled, and embase for the published studies in the duration june 2000 to february 2020 which were further shortlisted as per the inclusion and exclusion criteria of the study.The elder population considered from the selected studies was considered in an age of 65 years or more who were pre-fragile or fragile.Here, we included the clinical as well as randomized control trials.Results.After extracting the data, we measured the risk ratio for aerobic intervention for physical intervention group as 0.55 [95% confidence interval (c.i) as 0.29, 1.03], mobility/rehabilitation interventions were nonsignificant for both groups with reported risk ratio as 1.13 (95% c.i as 0.96, 1.33), muscular strength randomized control trails as a significant integrated outcome estimate over the mobility measure, where the risk ratio was obtained as 1.17 (95% c.i 1.00, 1.35), for the randomized control trials of the mixed interventions showed a significant integrated outcome over the measures of mobility with obtained risk difference 0.03 (95% c.i -0.03, 0.09) and significant effects for daily life activities for intervention group with odds ratio 0.98 (95% c.i was 0.68, 1.41).Conclusion.From the conducted systematic review and meta-analysis, we determined a low to medium authentication that different physical activities interventions are considered to be advantageous for the pre-fragile as well as the fragile elderly people.The studies are required to be more comprehensive and clear about defining the fragility so as to assure the determination and performing of such interventions into a clinical execution.

Journal: Computational and Mathematical Methods in Medicine (2022)
Publication types: Meta-Analysis;
A Ferroptosis-Related Gene Signature for Predicting Survival and Immunotherapy Effect in Renal Cancer

Most recently, no efficient prognostic indictor is present for kidney cancer.Thus, we aimed to build and validate a new prognostic gene signature for renal cancer patients using the cancer genomic atlas (tcga).Methods.A “time-dependent receiver operating characteristic (t roc)” curve was generated, and a log-rank test was performed to assess the performance of the biomarker in training and validation.A “ferroptosis-related gene signature” was developed.In different training and validations sets, t roc and log-rank test were used to validate the biomarker’s performance.Results.In the training set with a p value less than 0.01 and the validation set, the “gene signature” was significantly correlated with survival.Eventually, it was found that the ferroptosis-related gene signature was directly correlated with immune score and the score of tumor mutation, suggesting its role in predicting response to immunotherapy.Conclusion.We developed and validated a “ferroptosis-related gene signature” that can be sued for patients with kidney cancer.It can also assist in facilitating the plan for treatment and risk stratification.

Journal: Computational and Mathematical Methods in Medicine (2022)
Publication types: Research Article;
Application of VR Technology in Jewelry Display

As a special symbolic cultural carrier that reflects people’s material life and spiritual state, jewelry plays an increasingly important role in life.How can we accelerate brand promotion, promote jewelry product sales, and establish a rapid market response mechanism?High efficiency, high quality, and low cost to meet consumers’ increasingly personalized and diversified needs are the problems we currently need to solve.The purpose of this article is to explore the application of vr technology in jewelry displays and provide a brand new idea for jewelry display.In order to realize the virtualization of the jewelry design process, this article uses the cult 3d vr platform to complete the design and realization of the interactive function of the jewelry virtual model, uses the photoshop software to design the jewelry virtual display system interface, and finally completes the jewelry virtual display system in the dreamweaver software integration and release.Through detailed example application, the feasibility of the viewpoint of this subject was effectively verified.In this paper, the two algorithms brsk and surf are used in conjunction, and the multiscale expression characteristics of brisk in space and the rotation-invariant characteristics of surf are used.Studies have shown that the experimental results of the rotation performance of the method in this paper show that the accuracy is improved by 60%, and the time-consuming is relatively less.Therefore, under the premise of ensuring the rapidity, the method in this paper can guarantee the accuracy and time cost of control matching.

Journal: Mathematical Problems in Engineering (2021)
Publication types: Research Article;
Coaxiality of Stepped Shaft Measurement Using the Structured Light Vision

A method is proposed to measure the coaxiality of stepped shafts based on line structured light vision.In order to solve the repeated positioning error of the measured shaft, the light plane equation solution method is proposed using movement distance and initial light plane equation.In the coaxiality measurement model, the equation of the reference axis is obtained by the overall least square method through the center point coordinates of each intercept line on the reference axis.The coaxiality error of each shaft segment relative to the reference axis is solved based on the principle of minimum containment.In the experiment, the coaxiality measurement method is evaluated, and the factors that affect the measurement accuracy are analyzed.

Journal: Mathematical Problems in Engineering (2021)
Publication types: Research Article;
Application of Blockchain Technology in Supply Chain Finance of Beibu Gulf Region

Blockchain technology is a database that is operated by multiple parts and forms a chain structure through hash index.The blockchain uses multiple nodes and distributes multiple accesses to data, thereby reducing the dependence on the central internet server and avoiding the possibility of damage to the central server point due to data and data loss.Encryption technology is used to ensure its integrity and ensure that the data files stored in the blockchain are not tampered with or deleted maliciously.Blockchain technology has inherent advantages in supply chain finance with its technical attributes such as nontampering, distributed ledger, and traceability and has great potential to build trust to solve the main problems of supply chain finance, which is conducive to promoting financial development in the beibu gulf region.This article mainly introduces the application research of blockchain technology in supply chain finance in the beibu gulf region and intends to provide some ideas for the development of supply chain finance in the beibu gulf region combined with blockchain technology.This article proposes the application research methods of blockchain technology in supply chain finance in the beibu gulf region, including blockchain technology, supply chain financial risk evaluation on the blockchain, and supply chain finance game for relevant experiments.The experimental results of this article show that the average processing time of the algorithm of the designed blockchain supply chain financial system is 4.10 seconds, the algorithm processing efficiency is faster, and the relevant risks can be better assessed.

Journal: Mathematical Problems in Engineering (2021)
Publication types: Research Article;
A Cohort Study to Evaluate the Efficacy and Value of CT Perfusion Imaging in Patients with Metastatic Osteosarcoma after Chemotherapy

A case-control study was conducted to explore the efficacy of cohort study and value of ct perfusion imaging in patients with metastatic osteosarcoma after chemotherapy.Methods.Eighty patients with metastatic osteosarcoma treated in our hospital from march 2020 to december 2021 were divided into two groups.According to their different treatment methods, the chemotherapy+antiangiogenesis group had 36 cases and the chemotherapy group had 44 cases.All patients were scanned by 64-slice spiral ct before and after treatment.The differences of tumor volume and perfusion parameters before and after treatment were compared, and the correlation between perfusion parameters and tumor microvessel density (mvd) was analyzed.The receiver working curve (roc curve) was used to evaluate the efficacy of the two groups after chemotherapy.Results.Blood flow (bf), blood volume (bv), pallak blood volume (pbv), and time to start (tts) in the antitumor angiogenesis+chemotherapy group were significantly lower than those before treatment ( p &lt; 0.05 ).Microvessel density was positively correlated with ps, bf, bv, and pbv ( p &lt; 0.05 ).The reduction rate of bv and bf in the remission group after treatment was significantly higher than that in the nonremission group.When the bv and bf decline rates were 47.37% and 21.53% and the areas under the curve were 0.968 and 0.916, respectively, the diagnostic effect was the best.When the decrease rate of bv was 47.48% and the decrease rate of bf was 21.55%, the sensitivity was 94.72% and 89.56% and the specificity was 91.31% and 91.31%.Conclusion.The reduction rate of bv and bf in ct perfusion imaging is of high value in evaluating the efficacy of radiotherapy and chemotherapy in patients with nsclc and can provide more objective basis for observing the changes and judging the prognosis of osteosarcoma after treatment.

Journal: Computational and Mathematical Methods in Medicine (2022)
Publication types: Clinical Study;
Safety Investment Decision Problem without Probability Distribution: A Robust Optimization Approach

Accidents occur frequently, causing huge losses to enterprises and individuals.Safety investment is an important means to prevent accidents, but how much to invest is a dilemma.Previous studies have assumed that the demand of safety investment follows some probability distribution.In practice, the distribution information of safety investment is usually limited or difficult to obtain, i.e., it is unknown.To deal with this kind of problem without a probability distribution, we construct the measures of marginal accident loss (mal) and marginal opportunity loss (mol) from the perspective of demand uncertainty.Robust optimization technology is utilized to establish three robust optimization models, which are the absolute robust models (arm), deviation robust models (drm), and relative robust models (rrm).The results of numerical analysis show that mal is positively correlated with safety investment and mol is negatively correlated with the uncertainty of safety investment.The above robust optimization models in this study can be applied to different enterprise’s risk scenarios.Arm, drm, and rrm are suitable for high- and nonhigh-risk industries and other industries, respectively.

Journal: Mathematical Problems in Engineering (2020)
Publication types: Research Article;
Potential Benefits of Music Therapy on Stroke Rehabilitation

Stroke is associated with a high rate of disability and mortality, and survivors are usually accompanied with dysphagia, aphasia, motor dysfunction, cognitive impairment, depression, and other complications.In the past decades, many studies have been conducted to reveal the pathogenesis and pathological mechanisms of stroke.Furthermore, treatment methods have been developed that contribute to the elevated survival rate of stroke patients.Early rehabilitation poststroke is starting to be recognized as important and has been receiving increasing attention in order to further improve the quality of life of the patients.As an emerging method of poststroke rehabilitation, music therapy can help attenuate dysphagia and aphasia, improve cognition and motor function, alleviate negative moods, and accelerate neurological recovery in stroke patients.This review helps summarize the recent progress that has been made using music therapy in stroke rehabilitation and is aimed at providing clinical evidence for the treatment of stroke patients.

Journal: Oxidative Medicine and Cellular Longevity (2022)
Publication types: Research Article;
Multifactorial Analysis of Clinical Prognosis of Liver Metastasis and Vascular Intervention Combined with Ablation in Colorectal Cancer

Colorectal cancer is one of the leading causes of deaths in china.The initial stages of colorectal cancer can be treated by surgery, radiation, and chemotherapy.However, in the advanced stages, it warrants an application of multimodality treatment.With advances in the medical field, there are applications of new modality of treatment that could possibly provide the appropriate treatment for the advanced stage tumours.The first site of metastasis after colorectal cancer is the liver and the conventional treatment to cure the metastatic lesion involves the administration of chemotherapy.With further advancement, chemotherapy has been directly administered at the thorough transarterial chemoembolization (tace) which is a vascular intervention.With further advancement, the nonvascular intervention, such as radiofrequency ablations (rfas), has been administered to the patients.A large amount of data support the use of vascular intervention (tace) with ablation for hepatic carcinoma; there is no sufficient literature to support the application of the modality in the metastatic liver lesion.In this prospective observational study, we have enrolled 80 patients with metastatic liver lesion from the adenocarcinoma of colon or rectum, treated the patients with a combination of the tace and ablation therapy, and followed up the patients for a period of 3 years.A multivariate analysis of the various factors that influence the prognosis and outcome has been studied and it has been concluded that the combination therapy is medically beneficial for individuals with aggressive liver lesions, improving overall as well as progression-free life span.

Journal: Journal of Oncology (2022)
Publication types: Research Article;
Monitoring of Physical Fitness and Tactical Ability Based on Data-Driven Technology

Tennis is a competitive sport, which requires players to have good physical fitness and long-lasting endurance.Monitoring the physical training and technical and tactical abilities of tennis players is a necessary work to improve the physical fitness and competitive status of tennis players.Monitoring the physical training and technical and tactical capabilities of tennis players is necessary to improve their physical fitness and competitive status.Most of the traditional monitoring systems are incomplete, inaccurate, and inefficient, which can no longer meet the requirements of tennis training monitoring in the new era.Therefore, it is urgent to establish an efficient and more accurate tennis training monitoring system.With the rise of big data, data-driven technology has been concerned about and frequently used.It means using data as a production material, applying it in a scientific way to business operations, and giving continuous positive feedback to facilitate business optimisation.This study selected tennis sports training, physical fitness, and technical and tactical abilities as the monitoring object, and it analyzed the monitoring system combined with the grey relation algorithm and topsis algorithm.The experiment showed that the monitoring system based on data-driven technology can comprehensively and accurately monitor the physical ability and technical and tactical abilities of tennis sports training, and the accuracy improves by 5.9%.

Journal: Mobile Information Systems (2022)
Publication types: Research Article;
Exploring the Temporal Correlation of Sarcopenia with Bone Mineral Density and the Effects of Osteoblast-Derived Exosomes on Myoblasts through an Oxidative Stress–Related Gene

Sarcopenia is an age-related accelerated loss of muscle strength and mass.Bone and muscle are closely related as they are physically adjacent, and bone can influence muscle.However, the temporal association between bone mineral density (bmd) and muscle mass in different regions of the body after adjustment for potential indicators and the mechanisms by which bone influences muscle in sarcopenia remain unclear.Therefore, this study aimed to explore the temporal association between muscle mass and bmd in different regions of the body and mechanisms by which bone regulates muscle in sarcopenia.Here, cross-lagged models were utilized to analyze the temporal association between bmd and muscle mass.We found that low-density lipoprotein (ldl-c) positively predicted appendicular lean mass.Mean whole-body bmd (wbtot bmd), lumbar spine bmd (ls bmd), and pelvic bmd (pelv bmd) temporally and positively predicted appendicular lean mass, and appendicular lean mass temporally and positively predicted wbtot bmd, ls bmd, and pelv bmd.Moreover, this study revealed that primary mice femur osteoblasts, but not primary mice skull osteoblasts, induced differentiation of c2c12 myoblasts through exosomes.Furthermore, the level of long noncoding rna (lnc rna) taurine upregulated 1 (tug1) was decreased, and the level of lnc rna differentiation antagonizing nonprotein coding rna (dancr) was increased in skull osteoblast–derived exosomes, the opposite of femur osteoblast–secreted exosomes.In addition, lnc rna tug1 enhanced and lnc rna dancr suppressed the differentiation of myoblasts through regulating the transcription of oxidative stress–related myogenin (myog) gene by modifying the binding of myogenic factor 5 (myf5) to the myog gene promoter via affecting the nuclear translocation of myf5.The results of the present study may provide novel diagnostic biomarkers and therapeutic targets for sarcopenia.

Journal: Oxidative Medicine and Cellular Longevity (2022)
Publication types: Research Article;
Evaluation of Scientific and Technological Innovation Ability of Free Trade Zone Based on Random Forest Weighting Method

The scientific and technological innovation ability of the economic free trade zone is crucial to the depth and breadth of its economic development.There are too many subjective factors in the evaluation of the scientific and technological innovation ability of traditional economic free trade zones.In order to objectively evaluate the scientific and technological innovation ability of the free trade zone, this paper uses the random forest weighting method and the weighted linear combination to construct the evaluation index system, designs the evaluation model of the scientific and technological innovation ability of the free trade zone, and makes a specific analysis and evaluation based on the operation data of the economic and technological innovation ability of china’s four key free trade zones in 2020.The results show that the scientific and technological innovation ability of guangdong economic free trade zone is the strongest, followed by guangdong economic and trade zone, shanghai economic and trade zone, zhejiang economic and trade zone, and tianjin economic and trade zone; guangdong free trade zone has strong scientific and technological innovation ability.Compared with other free trade zones, guangdong’s main advantages lie in the integration and aggregation ability of the industrial chain, strong policy support, and talent attraction.The scientific and technological innovation ability forms a virtuous circle.The analysis of the model example shows that the introduction of the random forest weighting method into the scientific and technological evaluation of the free trade zone can more objectively compare and analyze the scientific and technological innovation ability of the free trade zone, which is of great significance to help the free trade zone find out the problems and shortcomings in the scientific and technological innovation ability and improve the level of scientific and technological innovation.

Journal: Mobile Information Systems (2022)
Publication types: Research Article;
Environmental Monitoring and Restoration of Ecological Cycle Index System Based on IoT Agriculture

Environmental factors have a direct impact on the development of agriculture, so it is particularly important to detect the environment of the agroecological cycle index system.Although there are some plans for environmental monitoring, most of them are environmental monitoring for a larger concept, but this study is specific to the actual object.This article takes farmland as the research object and comprehensively uses embedded technology, information monitoring technology, and network technology based on the analysis of the research status and system application of the farmland environmental monitoring system.This article studies and designs a real-time online remote monitoring system for farmland ecological environment based on embedded architecture and gprs technology.By using sensors to obtain farmland information, it is displayed on the monitoring center and mobile client, and data information is obtained in real time.It manages and protects the farmland environment in advance.This article measures and analyzes the data from the final experiment.The experimental results show that the monitoring system can accurately collect farmland data in real time.And through the embedded server and the internet, the data can be remotely transmitted in real time and displayed on the monitoring center and mobile client software.The results showed that pm2.5 was 30 μg/m3 at 20:00.The experimental data have the characteristics of real time and stability, which can meet the requirements of real-time network remote monitoring and transmission of data.

Journal: Scientific Programming (2022)
Publication types: Research Article;
Effects of Xuefu Zhuyu Granules on Patients with Stable Coronary Heart Disease: A Double-Blind, Randomized, and Placebo-Controlled Study

Despite advances in the drug treatment strategy for stable coronary heart disease (chd), the mortality of chd continues to rise.New or adjuvant treatments would be desirable for chd.Xuefu zhuyu granules are derived from the formula of traditional chinese medicine.To determine whether xuefu zhuyu granules might have adjuvant effects on stable chd, we conducted a controlled clinical trial.Patients with stable chd were enrolled and randomly assigned to receive xuefu zhuyu granules or placebo for 12 weeks in addition to their standard medications for the treatment of chd.The primary endpoints comprise the canadian cardiovascular society angina grading scale (ccs class), echocardiographic measures, seattle angina questionnaire (saq), and coronary artery ct.The secondary endpoints included the parameters of nailfold capillary measurement and cutaneous blood perfusion (cbp).After 12 weeks of follow‐up, there was a great improvement of the canadian cardiovascular society angina grading scale (ccs class) in the xuefu zhuyu group compared with the placebo group ( p &lt; 0.01).Also, a decrease was found in the percentage of patients with ccs class ii in the xuefu zhuyu group between follow‐up at 12 weeks and baseline ( p &lt; 0.01).We observed a significant increase in saq scores of physical limitation ( p &lt; 0.01) and treatment satisfaction ( p &lt; 0.05) in patients receiving xuefu zhuyu treatment at 12 weeks in comparison with those at baseline, but not in placebo treatment ( p &gt; 0.05).Amelioration in coronary artery stenosis in the xuefu zhuyu group was noted ( p &lt; 0.05).Xuefu zhuyu granule treatment led to great improvements in cutaneous blood perfusion at follow‐up of 12 weeks compared with placebo ( p &lt; 0.05).These findings suggest that on a background of standard medications, xuefu zhuyu granules have the ability to further improve the prognosis of patients with stable chd.

Journal: Oxidative Medicine and Cellular Longevity (2021)
Publication types: Clinical Study;