syedzayyan/paper_mill_benchmark huggingface dataset:
Farm typology of smallholders integrated farming systems in Southern Coastal Plains of Kerala, India.

Adoption of an integrated farming system (ifs) is essential to achieve food and nutritional security in small and marginal holdings.Assessment of ifs to know the resource availability and socio-economic condition of the farm household, farm typology plays a critical role.In this regard, a sample survey of 200 marginal households practicing mixed crop-livestock agriculture was conducted during 2018-2019 at southern coastal plains, which occupies 19,344 ha in thiruvananthapuram district, kerala, india.Farming system typology using multivariate statistical techniques of principal component analysis and cluster analysis characterized the diverse farm households coexisting within distinct homogenous farm types.Farming system typology identified four distinct farm types viz.Resource constrained type-1 households with small land owned, high abundance of poultry, very low on-farm income, constituted 46.5%; resource endowed type-2 households oriented around fruit and vegetable, plantation crop, with a moderate abundance of large ruminant and poultry, high on-farm income, constituted 12.5%; resource endowed type-3 household oriented around food grain, extensive use of farm machinery, with a moderate abundance of large ruminant, low on-farm income, constituted 21.5%; and resource endowed type-4 household oriented around fodder, with high abundance of large ruminant, medium on-farm income, constituted 19.5% of sampled households.Constraint analysis using constraint severity index assessed the severity of constraints in food grain, horticulture, livestock, complementary and supplementary enterprises in each farm type, which allowed targeted farming systems interventions to be envisaged to overcome soil health problems, crops and animal production constraints.Farming system typology together with constraint analysis are therefore suggested as a practical framework capable of identifying type-specific farm households for targeted farming systems interventions.

Journal: Scientific reports (2022)
Publication types: Journal Article;Research Support, Non-U.S. Gov't
Decorative Magnolia Plants: A Comparison of the Content of Their Biologically Active Components Showing Antimicrobial Effects.

Magnoliaplants are used both as food supplements and as cosmetic and medicinal products.The objectives of this work consisted of preparing extracts from leaves and flowers of eight magnoliaplants, and of determining concentrations of magnolol (1 to 100 mg·g-1), honokiol (0.11 to 250 mg·g-1), and obovatol (0.09 to 650 mg·g-1), typical neolignans for the genus magnolia, in extracts made by using a methanol/water (80/20) mixture.The tested magnoliaplants, over sixty years old, were obtained from průhonický park (prague area, czech republic):m.Tripetala mtr 1531,m.Obovata mob 1511, and six hybrid plants magnolia × pruhoniciana, results of a crossbreeding of m.Tripetala mtr 1531 with m.Obovata mob 1511.The identification of neolignans was performed by hrms after a reversed-phase high-performance liquid chromatography (rp-hplc) fractionation of an extract from m.Tripetala mtr 1531.The highest concentrations of neolignans were found in the flowers, most often in their reproductive parts, and obovatol was the most abundant in every tested plant.The highest concentrations of neolignans were detected in parent plants, and lower concentrations in hybrid magnolias.Flower extracts from the parent plants m.Tripetala mtr 1531 and m.Obovata mob 1511, flower extracts from the hybrid plants magnolia × pruhoniciana mpr 0271, mpr 0151, and mpr 1531, and leaf extract from the hybrid plant magnolia × pruhoniciana mpr 0271 inhibited growth of staphylococcus aureus.

Journal: Plants (Basel, Switzerland) (2020)
Publication types: Journal Article
Instance-Based Genre-Specific Music Emotion Prediction with An EEG Setup.

This paper explores a novel direction in music-induced emotion (music emotion) analysis - the effects of different genres on the prediction of music emotion.We aim to compare the performance of various classifiers in the prediction of the emotion induced by music, as well as to investigate the adaptation of advanced features (such as asymmetries) in improving classification accuracy.The study is supported by real-world experiments where 10 subjects listened to 20 musical pieces from 5 genres- classical, heavy metal, electronic dance music, pop and rap, during which electroencephalogram (eeg) data were collected.A maximum 10-fold cross-validation accuracy of 98.4% for subject-independent and 99.0% for subject-dependent data were obtained for the classification of short instances of each song.The emotion of popular music was shown to have been most accurately predicted, with a classification accuracy of 99.6%.Further examination was conducted to investigate the effect of music emotion on the relaxation of subjects while listening.

Journal: Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference (2018)
Publication types: Journal Article
Solution Processing of Topochemically Converted Layered WO3for Multifunctional Applications.

Solution processing of nanomaterials is a promising technique for use in various applications owing to its simplicity and scalability.However, the studies on liquid-phase exfoliation (lpe) of tungsten oxide (wo3) are limited, unlike others, by a lack of commercial availability of bulk wo3with layered structures.Herein, a one-step topochemical synthesis approach to obtain bulk layered wo3from commercially available layered tungsten disulfide (ws2) by optimizing various parameters like reaction time and temperature is reported.Detailed microscopic and spectroscopic techniques confirmed the conversion process.Further, lpe was carried out on topochemically converted bulk layered wo3in 22 different solvents; among the solvents studied, the propan-2-ol/water (1 : 1) co-solvent system appeared to be the best.This indicates that the possible values of surface tension and hansen solubility parameters for bulk wo3could be close to that of the co-solvent system.The obtained wo3dispersions in a low-boiling-point solvent enable thin films of various thickness to be fabricated by using spray coating.The obtained thin films were used as active materials in supercapacitors without any conductive additives/binders and exhibited an areal capacitance of 31.7 m f cm-2at 5 m v s-1.Photo-electrochemical measurements revealed that these thin films can also be used as photoanodes for photo-electrochemical water oxidation.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) (2021)
Publication types: Journal Article
Measuring Emotion Dysregulation in Children With Attention-Deficit/Hyperactivity Disorder: Revisiting the Factor Structure of the Emotion Regulation Checklist.

Emotion dysregulation (ed) is prevalent among youth with attention-deficit/hyperactivity disorder (adhd) and significantly impacts functioning.Nuanced measurement of ed is central to understanding its role in this disorder and informing treatment approaches.The present study examined the factor structure of the emotion regulation checklist (erc) among children with adhd with and without oppositional defiant disorder (odd).Exploratory factor analysis (efa) conducted in a sample of 328 youth (mean age = 6.08) with adhd indicated a four-factor solution, comprised of the following factors: negative emotion lability, positive emotion lability, socially appropriate affect, and socially incongruent affect.The negative and positive emotion lability subscales assess the reactivity of negatively and positively valenced emotions, respectively.The socially appropriate and socially incongruent affect subscales provide an assessment of social-emotional functioning.All subscales discriminated between children with adhd only and adhd with co-morbid odd, such that children with odd had greater emotional lability and social-emotional difficulties.This revised factor structure of the erc facilitates a uniquely brief, yet multifaceted and specific, assessment of emotional difficulties in children with adhd that can inform treatment planning and operationalize emotional reactivity and social-emotional functioning in future research efforts.

Journal: Behavior therapy (2022)
Publication types: Journal Article;Research Support, N.I.H., Extramural
The Effect of Proprotein Convertase Subtilisin Kexin Type 9 Inhibitors on Circulating Endothelial Progenitor Cells in Patients with Cardiovascular Disease.

Circulating endothelial progenitor cells (c epcs) are vital to vascular repair by re-endothelialization.We aimed to explore the effect of proprotein convertase subtilisin kexin type 9 inhibitors (pcsk9i) on c epcs hypothesizing a possible pleiotropic effect.Methods patients with cardiovascular disease (cvd) were sampled for c epcs at baseline and following the initiation of pcsk9i.C epcs were assessed using flow cytometry by the expression of cd34(+)/cd133(+)and vascular endothelial growth factor receptor (vegfr)-2(+), and by the formation of colony-forming units (cfus) and production of vegf.Results our cohort included 26 patients (median age 68 (iqr 63, 73) years; 69% male).Following 3 months of treatment with pcsk9i and a decline in low-density lipoprotein cholesterol levels (153 (iqr 116, 176) to 56 (iqr 28, 72) mg/dl), p < 0.001), there was an increase in cd34(+)/cd133(+)and vegfr-2(+)cell levels (0.98% (iqr 0.37, 1.55) to 1.43% (iqr 0.90, 4.51), p = 0.002 and 0.66% (iqr 0.22, 0.99) to 1.53% (iqr 0.73, 2.70), p = 0.05, respectively).Functionally, increase in epcs-cfus was microscopically evident following treatment with pcsk9i (1 cfus (iqr 0.0, 1.0) to 2.5 (iqr 1.5, 3), p < 0.001) with a concomitant increase in epc's viability as demonstrated by an mtt assay (0.15 (iqr 0.11, 0.19) to 0.21 (iqr 0.18, 0.23), p < 0.001).Vegf levels increased following pcsk9i treatment (57 (iqr 18, 24) to 105 (iqr 43, 245), p = 0.006).Conclusions patients with cvd treated with pcsk9i demonstrate higher levels of active c epcs, reflecting the promotion of endothelial repair.These findings may represent a novel mechanism of action of pcsk9i.

Journal: Cardiovascular drugs and therapy (2022)
Publication types: Journal Article;Research Support, Non-U.S. Gov't
Controlled Complexity: Optimized Systems to Study the Role of the Gut Microbiome in Host Physiology.

The profound impact of the gut microbiome on host health has led to a revolution in biomedical research, motivating researchers from disparate fields to define the specific molecular mechanisms that mediate host-beneficial effects.The advent of genomic technologies allied to the use of model microbiomes in gnotobiotic mouse models has transformed our understanding of intestinal microbial ecology and the impact of the microbiome on the host.However, despite incredible advances, our understanding of the host-microbiome dialogue that shapes host physiology is still in its infancy.Progress has been limited by challenges associated with developing model systems that are both tractable enough to provide key mechanistic insights while also reflecting the enormous complexity of the gut ecosystem.Simplified model microbiomes have facilitated detailed interrogation of transcriptional and metabolic functions of the microbiome but do not recapitulate the interactions seen in complex communities.Conversely, intact complex communities from mice or humans provide a more physiologically relevant community type, but can limit our ability to uncover high-resolution insights into microbiome function.Moreover, complex microbiomes from lab-derived mice or humans often do not readily imprint human-like phenotypes.Therefore, improved model microbiomes that are highly defined and tractable, but that more accurately recapitulate human microbiome-induced phenotypic variation are required to improve understanding of fundamental processes governing host-microbiome mutualism.This improved understanding will enhance the translational relevance of studies that address how the microbiome promotes host health and influences disease states.Microbial exposures in wild mice, both symbiotic and infectious in nature, have recently been established to more readily recapitulate human-like phenotypes.The development of synthetic model communities from such "wild mice" therefore represents an attractive strategy to overcome the limitations of current approaches.Advances in microbial culturing approaches that allow for the generation of large and diverse libraries of isolates, coupled to ever more affordable large-scale genomic sequencing, mean that we are now ideally positioned to develop such systems.Furthermore, the development of sophisticatedin vitrosystems is allowing for detailed insights into host-microbiome interactions to be obtained.Here we discuss the need to leverage such approaches and highlight key challenges that remain to be addressed.

Journal: Frontiers in microbiology (2021)
Publication types: Journal Article;Review
Position of lips and tongue in rest in newborns with and without ankyloglossia.

Verify the position of lips and tongue at rest in newborns with and without ankyloglossia.Methods cross-sectional study, carried out with 130 newborns in university hospital.Data collection was performed by the researcher and speech-language pathologists from the hospital.Information on gestational age, sex, weight, height and days of life was collected.The position of the lips and tongue at rest was evaluated through visual inspection with the newborns asleep.After the newborns were awakened, neonatal screening of the validated protocol for the evaluation of the lingual frenulum for infants was performed to detect the alteration of the lingual frenulum.The data obtained were described and submitted to statistical analysis using the chi-square test to verify the association between the position of the lips with the tongue and to compare the position of the lips and tongue with and without ankyloglossia.The mann-whitney test was used to verify the behavior of the variables the differed between newborns with and without ankyloglossia.The significance level of 5% was adopted.Results when comparing the data, a significant difference was found between: weight and height with and without ankyloglossia; position of lips and tongue.An association between the position of the tongue and lips with and without ankyloglossia was also found.Conclusion newborns without alteration of the lingual frenulum have a tendency to remain with their lips closed and their tongue elevated during rest and newborns with ankyloglossia have a tendency to keep their lips parted and their tongue low during rest.

Journal: CoDAS (2021)
Publication types: Journal Article
The pathological and molecular genetic landscape of the hereditary renal cancer predisposition syndromes.

It is estimated that 5-8% of renal tumours are hereditary in nature, with many inherited as autosomal-dominant.These tumours carry a unique spectrum of pathological and molecular alterations, the knowledge of which has expanded in recent years.Due to this knowledge, many advances in the treatment of these tumours have been achieved.In this review, we summarize the current understanding of the genetic renal neoplasia syndromes, clinical and pathological presentations, molecular pathogenesis, advances in therapeutic implications and targeted therapy.

Journal: Histopathology (2022)
Publication types: Journal Article;Review
Etiology and efficacy of anti-microbial treatment for community-acquired pneumonia in adults requiring hospital admission in Ukraine.

And aim empiric therapy of community-acquired pneumonia (cap) remains the standard care and guidelines are mostly based on published data from the united states or europe.In this study, we determined the bacterial etiology of cap and evaluated the clinical outcomes under antimicrobial treatment of cap in ukraine.Methods a total of 98 adult subjects with cap and port risk ii-iv were recruited for the study.The sputum diagnostic samples were obtained from all patients for causative pathogen identification.Subjects were randomly assigned in a 1:1 ratio to receive delafloxacin 300 mg (n=51) or moxifloxacin 400 mg (n=47) with blinding placebo.The switch to oral treatment was after a minimum of 6 iv doses according to clinical criteria.The total duration of antibacterial treatment was 5-10 days.In vitro susceptibility of pathogens to delafloxacin and other comparator antibiotics was determined.Results the most frequently isolated pathogens in adults with cap were s.Pneumoniae - 19.5%, m.Pneumoniae - 15.3%, h.Influenzae - 13.2%, s.Aureus - 10.5%, k.Pneumoniae - 10.1%, and h.Parainfluenzae - 6.4%.All isolates of s.Pneumoniae, s.Aureus, m.Pneumoniae had sufficient susceptibility to appropriate antibiotics.9.0% of h.Influenzae strains were susceptible to azithromycin.94.8 % of patients had a successful clinical response to delafloxacin at the end of treatment and 93.9 % - at test-of-cure.Conclusions in ukraine, the major bacterial agents that induced cap in adults were s.Pneumoniae, m.Pneumoniae, h.Influenzae, s.Aureus, k.Pneumoniae, h.Parainfluenzae, e.Cloacae, l.Pneumophila.Delafloxacin is a promising effective antibiotic for monotherapy for cap in adults and could be used in cases of antimicrobial-resistant strains.

Journal: Acta bio-medica : Atenei Parmensis (2022)
Publication types: Journal Article;Randomized Controlled Trial
Application of omental interposition to reduce pancreatic fistula and related complications in pancreaticoduodenectomy: A propensity score-matched study.

The life-threatening complications following pancreatoduodenectomy (pd), intra-abdominal hemorrhage, and postoperative infection, are associated with leaks from the anastomosis of pancreaticoduodenectomy.Although several methods have attempted to reduce the postoperative pancreatic fistula (popf) rate after pd, few have been considered effective.The safety and short-term clinical benefits of omental interposition remain controversial.Aim to investigate the safety and feasibility of omental interposition to reduce the popf rate and related complications in pancreaticoduodenectomy.Methods in total, 196 consecutive patients underwent pd performed by the same surgical team.The patients were divided into two groups: an omental interposition group (127, 64.8%) and a non-omental interposition group (69, 35.2%).Propensity score-matched (psm) analyses were performed to compare the severe complication rates and mortality between the two groups.Results following psm, the clinically relevant popf (cr-popf, 10.1%vs24.6%;p= 0.025) and delayed postpancreatectomy hemorrhage (1.4%vs11.6%;p= 0.016) rates were significantly lower in the omental interposition group.The omental interposition technique was associated with a shorter time to resume food intake (7 dvs8 d;p= 0.048) and shorter hospitalization period (16 dvs21 d;p= 0.031).Multivariate analyses showed that a high body mass index, nonapplication of omental interposition, and a main pancreatic duct diameter < 3 mm were independent risk factors for cr-popf.Conclusion the application of omental interposition is an effective and safe approach to reduce the cr-popf rate and related complications after pd.

Journal: World journal of gastrointestinal surgery (2022)
Publication types: Journal Article
Tuberculous aortitis in an human immunodeficiency virus-positive Ivorian migrant: A case report.

We report an unusual case of a 35-year-old ivorian migrant with an abdominal mass and medical history relevant for human immunodeficiency virus-2 positivity with a cd4/cd8 ratio of 0.63; mantoux and lymphocyte stimulation tests (quanti feron) were positive.3d-ct images revealed a voluminous non-homogeneous retroperitoneal mass in the right abdominal region presenting no significant contrast impregnation.Thoraco-abdominal aorta presented diffuse-altered morphology with multiple ectasias throughout its course and an aneurysm at the level of the subrenal tract.The patient underwent vascular surgery.Mycobacterium tuberculosis complex was detected by polymerase chain reaction performed on intraoperative tissue specimens.Postoperative course was uneventful.After surgery, 3d-ct images showed no signs of malfunction of the prosthesis.At last, at 6-month follow-up, the patient was well.Cross-sectional imaging techniques, such as contrasted-ct, are essential and allow for making diagnosis, assessing disease activity, and evaluating post-treatment condition.3d reconstruction permits an appropriate patient care by means of an excellent visualization and staging of the disease process.

Journal: International journal of STD & AIDS (2021)
Publication types: Case Reports;Journal Article
Comparison of Efficacy Between Vaginal Sildenafil and Granulocyte-Colony Stimulating Factor (G-CSF) in Improving Endometrial Thickness (ET) in Infertile Women.

Infertility is presently an emanating preventive medicine issue with some severe societal repercussions associated with it.In india, approximately a score percent of couples bear the burden of infertility.Moreover, the declining fertility rates despite effective artificial reproductive techniques and increasing development of modern reproductive medicine from the last two censuses pose an alarm to the demographic progression data.Many studies have highlighted the importance of shifting the research focus to endometrial receptivity for increasing clinical pregnancy.Objective this research aims to compare the efficacy of treatments of vaginal sildenafil citrate and granulocyte-colony stimulating factor (g-csf) intrauterine injection in increasing endometrial thickness (et).Methodology this was a randomized control trial (rct) conducted over a two months period.Women seeking infertility treatment were recruited from the hospital's gynecological outpatient department (opd).After the subjects gave informed consent, their history, clinical examination, and investigations were assessed.From the sixth day of the menstrual cycle, group a and group b had serial trans-vaginal ultra-sonographic evaluations for baseline endometrial thickness measurements.From day six to day 12 of the menstrual cycle, patients of group a were requested to self-administer per vaginal sildenafil citrate 25 mg every six hours.Et was evaluated sonographically on day 12 and day 14 of their menstrual cycle.Patients of group b received g-csf 300 mcg/mlasintrauterine instillation on day 10 and were evaluated sonographically on day 12 and day 14 of their menstrual cycle.Patients then underwent additional therapy in the form of intrauterine injection (iui), intracytoplasmic sperm injection with/without embryo transfer (icsi/et), or a natural cycle.Paired as well as unpaired t-tests were applied to the study groups to detect significant differences in the measurement of endometrial thickness before and after treatment.Results it was noticed that both sildenafil and g-csf are agents for increasing endometrial thickness.The mean increase in endometrial thickness in the sildenafil treated group was 3.87 mm, while the mean increase in endometrial thickness in g-csf treated group was 3.27 mm.Conclusion this study has evidence of better results in improving endometrial thickness in infertile women by using vaginal sildenafil with respect to endometrial growth with an intrauterine infusion of granulocyte colony-stimulating factor (filgrastim, g-csf).

Journal: Cureus (2022)
Publication types: Journal Article