syedzayyan/paper_mill_benchmark huggingface dataset:
Investigation of the Clinical Effect of New Shoulder Joint Abduction Frame in Humeral Fracture Patients after Arthroscopic Shoulder Surgery

This work is organized to analyze the clinical effects of new shoulder joint abduction frame on the bone metabolic markers, shoulder joint function, and visual analogue scale (vas) of humeral fracture patients undergoing arthroscopic surgery.Methods.118 patients with humeral fracture who planned to undergo shoulder surgery in our hospital from november 2018 to june 2021 were selected as the study objects and were divided into two groups according to the random number method, with 59 patients in each group.The patients in the two groups were subjected to arthroscopic shoulder surgery.New shoulder joint abduction frame was used for shoulder joint fixation in the abduction frame group, and sling was used for shoulder joint fixation in the sling group after surgery.The duration of fixation was 4-6 weeks.Finally, the prognostic indicators, complications, and serum bone metabolism levels in 4 and 6 weeks after surgery, shoulder joint function (neer score), vas score before surgery and after 3 and 6 months of surgery, and excellent or good rate of shoulder joint activity after 6 months of surgery were compared between the two groups.Results.The postoperative fracture healing time and start time of shoulder joint training were shorter, and the humeral varus angle and femur height loss were smaller in the abduction frame group than in the sling group ( p &lt; 0.05 ).There was no significant difference in the total incidence of complications between the two groups (3.39% and 13.56%, respectively) ( p &gt; 0.05 ).After 4 or 6 weeks of surgery, the levels of serum osteoprotegerin (opg) and carboxyterminal propeptide of type i procollagen (picp) were increased but the levels of tartrate-resistant acid phosphatase-5b (trap-5b) were decreased in the two groups with more significant differences in the abduction frame group ( p &lt; 0.05 ).After 6 months of follow-up, 2 cases were lost to follow-up in the abduction frame group and 3 cases in the sling group.Neer scores were increased, while vas scores were decreased in the two groups in the third or sixth months after surgery with significant differences in the abduction frame group ( p &lt; 0.05 ).The excellent or good rate of shoulder joint activity was 94.74% (54/57) in the abduction frame group, significantly higher than that in the sling group (80.36%; 45/56) ( p &lt; 0.05 ).Conclusion.The fixation effect of new shoulder joint abduction frame is significant after arthroscopic surgery, and patients can carry out functional training as early as possible, which is helpful to promote fracture healing, relieve pain, and restore shoulder joint function with high safety.

Journal: Computational and Mathematical Methods in Medicine (2022)
Publication types: Clinical Study;
Intravoxel Incoherent Motion Diffusion-Weighted Imaging and 3D-ASL to Assess the Value of Ki-67 Labeling Index and Grade in Glioma

To determine the proportion of intravoxel incoherent motion diffusion-weighted images (ivim-dwi) and three-dimensional arterial circulation markers (3d-asl) in ki-67 labeling index (ki-67 li) and glioma grading.Methods.According to the classification of diseases of the central nervous system dealt with by who in 2007, patients with stage ii glioma were classified as low ( n = 20 ) and patients with stages iii-iv were divided into higher levels ( n = 22 ).Prior to surgery, brain mri, ivim-dwi, and 3d-asl were performed in all patients, and the actual water molecular diffusion coefficient ( d ), microcirculation coefficient ( d ∗ ), blood flow fraction ( f ), and cerebral blood flow (cbf) were measured.A rank sum (mann–whitney u test) was used to compare the four upper and lower level ki-67 li measurements.Spearman’s method is used to identify the relationship between 4 groups of quantification and ki-67 li.Reciprocal grafting (roc) curves were used to measure the diagnosis of four groups of glioma grading defects.Results.There were significant differences in d , d ∗ , f , and cbf between the solid region of the tumor and the normal white matter contralateral to it ( p &lt; 0.05 ).The significant differences of r d , r d ∗ , r f , and r cbf were shown between patients with low-grade glioma and high-grade glioma ( p &lt; 0.05 ).Ki-67 li was found to have negative correlation with r d ( r = 00.693 , p &lt; 0.001 ) and r f ( r = 00.539 , p &lt; 0.001 ), but similarly correlated with r cbf ( r = 0.665 , p &lt; 0.001 ) in patients with glioma.Recipient efficacy for predicting advanced and secondary glioma from r d , r f , r d ∗ , r cbf, and ki-67 li raises aucs of 0.819, 0.747, 0.719, 0.836, and 0.907, respectively.Conclusion.Ivim-dwi has good application value for preoperative grading of glioma.

Journal: Scanning (2022)
Publication types: Research Article;
Intervention Effect of Rapid Rehabilitation Nursing Combined with Continuous Nursing after Discharge on Patients with Cerebral Infarction in Recovery Period and the Changes in Motor Function, Mental State, and Quality of Life

To explore the effect of rapid rehabilitation nursing combined with continuous nursing after discharge on patients with cerebral infarction (ci) in recovery period and its influence on motor function, mental state, and quality of life.Methods.From january 2018 to december 2020, 136 patients with ci in recovery period were selected and randomly divided into control group (n = 68) and observation group (n = 68).The control group was given routine nursing, and the observation group was given rapid rehabilitation nursing combined with continuous nursing after discharge.The general clinical data of the two groups were recorded, and the nursing efficiency, modified barthel index scale (mbi), stroke patients motor assessment scale (mas), self-rating anxiety and depression scale (sas and sds), and quality of life assessment scale (qli) were compared between the two groups.Results.The nursing effective rate of the observation group (94.12%, 64/68) was higher than that of the control group (82.35%, 56/68) ( p &lt; 0.05 ).The mbi score, mas score, and qli score in the observation group were higher than those in the control group, while the sas and sds scores in the observation group were lower than those in the control group ( p &lt; 0.05 ).Conclusion.Rapid rehabilitation nursing combined with continuous nursing after discharge can promote the rapid recovery of patients with ci in recovery period, which can improve the patient’s motor function, reduce unhealthy psychology, and improve the quality of life.

Journal: Evidence-Based Complementary and Alternative Medicine (2021)
Publication types: Clinical Study;
Intelligent Scanning Detection System of Muscle Exercise Fatigue Based on Surface Electromyography

In order to use the surface emg signal to automatically detect the muscle fatigue state, a research method of the muscle exercise fatigue intelligent scanning detection system based on surface emg was proposed, and the s emg signal features of 10 subjects before and after fatigue were extracted.A time-varying parameter autoregressive model is established.By introducing the legendre basis function, the parameter identification of the linear nonstationary process is transformed into the parameter identification of the linear time-invariant system.Combined with the correlation index, the optimal legendre base function dimension of the time-varying system parameter estimation can be obtained, then the best model fitting effect can be obtained, and the time-invariant parameters are solved by the least square method.Using the rate of change of the first time-varying parameter (arc1) of the autoregressive model before and after fatigue as an index to detect muscle fatigue sensitivity, a two-tailed t test was used to compare the mean power frequency (mpf) and the median frequency (mf) with the rate of change.The results showed that the change rates of arc1, mpf, and mf before and after fatigue were 34.33 % ± 2.5 % , 68 % + 2.03 % , and 22.80 % + 2.19 % , which were 41% and 25%, respectively.The rate of change of acr1 was significantly higher than that of mpf and mf ( p &lt; 0.05 ).When detecting muscle fatigue by s emg signal, it has the advantages of short time and high sensitivity.It can be used for online real-time analysis of muscle fatigue, providing a potential analysis tool for limb muscle strain, rehabilitation, and ergonomics assessment.

Journal: Scanning (2022)
Publication types: Research Article;
Intelligent Algorithm-Based Coronary Angiography Characteristics of Acute Non-ST-Segment Elevation Myocardial Infarction Patients with Different Genders

This study was aimed at comparing the characteristics of coronary angiography based on intelligent algorithm in patients with acute non-st-segment elevation myocardial infarction (nstemi) of different genders.Methods.Eighty patients were selected to segment the coronary angiogram using the convolutional neural network (cnn) algorithm, the input layer of the cnn was used to receive the image dataset, and three-dimensional data were input during semantic segmentation to achieve automatic segmentation of the target features.Segmentation results were quantitatively assessed by accuracy (acc), sensitivity (se), specificity (sp), and dice coefficient (dice).The characteristics of coronary angiography were compared between the two groups.Results.The cnn algorithm had good segmentation effect, complete vessel extraction, and little noise, and acc, se, sp, and dice were 90.32%, 93.39%, 91.25%, and 89.75%, respectively.The proportion of diabetes mellitus was higher in female patients with nstemi (68.8%) than that in male patients (46.3%); the proportion of the left main coronary artery (lm) and left anterior descending artery (lad) was lower in the female group (7.5%, 41.3%) than that in the male group (13.8%, 81.3%), and the difference between the two groups was statistically significant ( p &lt; 0.05 ).Conclusion.The cnn algorithm achieves accurate extraction of vessels from coronary angiographic images, and women with diabetes and hyperlipidemia are more likely to have nstemi than men, especially the elderly.

Journal: Computational and Mathematical Methods in Medicine (2022)
Publication types: Clinical Study;
Influencing Factors on the Use of Tetrahydrobiopterin in Patients with Phenylketonuria

To explore and analyze the influencing factors of tetrahydrobiopterin therapy in patients with phenylketonuria.Methods.86 children with phenylketonuria (pku) diagnosed and treated in our hospital from february 2019 to september 2021 were randomly enrolled.All the children underwent coenzyme hydroxybiopterin and urinary pterin spectrum analysis, and the children with deficiency received gene mutation testing.Results.The results of urine pterin analysis showed that 82 patients had higher urinary n and b contents than the normal reference values, with the n/b slightly higher than the normal b% within the normal range.4 patients had extremely high urinary n/b and b% &lt;5% and were diagnosed as bh4 deficiency caused by 6-pyruvoyl-tetrahydropterin synthase (ptps) deficiency, and a combined stress test was performed.The blood phe level was (720–1200) μmol/l 3 h after phe loading, and the blood phe concentration decreased to (120–240) μmol/l 4–6 h after oral administration of 7.5 mg/kg bh4 tablet.After one week of treatment, the blood phe concentration decreased significantly to 239 ± 173 μmol/l, with a decrease rate of 52.14 ± 25.28%.It shows that the application of tetrahydrobiopterin intervention therapy is effective in patients with pku.The results of the full-length c dna analysis of the ptps gene showed that a total of 4 gene mutations were found.A c ⟶ t substitution occurred at the 259th base, and the 87th proline (pro) in the coding region was converted to serine (ser) (p87s).G ⟶ a substitution at base 286 converts aspartic acid (asp) at position 96 of the coding region to asparagine (asn) (d96n).A ⟶ g substitution occurs at the 155th base to convert asparagine (asn) at position 52 of the coding region to serine (ser) (n52s).G ⟶ c substitution occurs at the 430th base to convert glycine at position 144 (gly) to arginine (arg) (g144r).G144r is a new mutation type.The gene mutation types of the 4 patients were p87s/d96n, n52s/g144r, d96n/p87s, and p87s/p87s, all of which were from their parents, which conformed to the law of autosomal recessive inheritance.Conclusion.Pku is caused by the defect of phenylalanine hydroxylase activity in children, which causes phenylalanine metabolism disorder, and tetrahydrobiopterin intervention therapy can affect the activity of phenylalanine hydroxylase, increase the decline rate of blood phe, significantly reduce the level of phenylalanine in children, and promote intellectual recovery.The dose of tetrahydrobiopterin should be tailored, with small doses for mild phenotypes and long-term treatment using even smaller doses.

Journal: Evidence-Based Complementary and Alternative Medicine (2022)
Publication types: Research Article;
Influence of Bushen Tiaochong Cycle Therapy on Th1/Th2 Deviation, Sex Hormone Level, and Pregnancy Outcome of Alloimmune Recurrent Spontaneous Abortion

To analyze the influence of bushen tiaochong cycle therapy on th1/th2 deviation, sex hormone level, and pregnancy outcome of alloimmune recurrent spontaneous abortion (rsa).Methods.From august 2018 to april 2020, 130 patients with alloimmune rsa who met the inclusion criteria were randomly divided into the control group (n = 65) and the study group (n = 65).The former received lymphocyte immunotherapy (lit), and the latter received bushen tiaochong cycle therapy on the basis of lit.The treatment ended at 12 w of pregnancy.The total score of traditional chinese medicine (tcm) syndromes, th1 cytokine (il-2), th2 cytokine (il-10), and related hormones (chorionic gonadotropin (h cg) and progesterone (p)) were compared between the two groups before and after treatment.The positive rate of blocking antibody (ba), pregnancy success rate, and preterm birth rate were counted.Result.After treatment, the total score of tcm syndromes, il-2 level, and th1/th2 ratio in the two groups decreased significantly, while the levels of il-10, h cg, and p increased significantly, and the study group improved significantly compared with the control group ( p &lt; 0.05 ).The positive rate of ba and pregnancy success rate in the study group were higher than those in the control group ( p &lt; 0.05 ).There was no significant difference in the preterm birth rate between the two groups ( p &gt; 0.05 ).Conclusion.On the basis of routine western medicine treatment, a combined application of bushen tiaochong cycle therapy can significantly improve the th1/th2 deviation, serum sex hormone level, and pregnancy outcome in patients with alloimmune rsa.

Journal: Evidence-Based Complementary and Alternative Medicine (2021)
Publication types: Research Article;
Improved Cardiac Function and Attenuated Inflammatory Response by Additional Administration of Tirofiban during PCI for ST-Segment Elevation Myocardial Infarction Patients

St-segment elevation myocardial infarction (stemi) is one of the acute coronary syndromes, and it is the main cause of cardiac death worldwide.The purpose of this study was to investigate whether tirofiban improves cardiac function and attenuates inflammatory response in stemi patients undergoing percutaneous coronary intervention (pci).From may 2016 to may 2019, a total of 124 patients who admitted into our hospital due to stemi fulfilled inclusion and exclusion criteria and were randomly assigned to pci + tirofiban and pci groups, 62 cases per groups.Intravenous administration of 10 μg kg−1 min−1 tirofiban was performed 30 min prior to pci.During pci, tirofiban infusion through a micropump with 0.15 μg kg−1 min−1 lasted for 48 h.It was found that the pci + tirofiban group was significantly different from the pci group in total corrected timi frame count (ctfc) after pci (15.88 ± 5.11 vs.22.47 ± 6.26, p &lt; 0.001 ).At day 7 and day 30 post-pci, a significant time-dependent decrease in the levels of brain natriuretic peptide (bnp), cardiac troponin i (c tn i), and creatine kinase isoenzyme (ck-mb) in both groups was observed after pci ( p &lt; 0.001 ).More importantly, the patients in the pci + tirofiban group had much lower levels of bnp, c tn i, and ck-mb compared with those in the pci group at days 7 and 30 post-pci ( p &lt; 0.001 ).At day 7 following pci, the left ventricular ejection fraction (lvef) was statistically higher in the pci + tirofiban group than in the pci group ( p &lt; 0.05 ).At day 30 post-pci, increased lvef concomitant with reduced left ventricular end diastolic diameter (lvedd) and left ventricular end systolic diameter (lvesd) was observed in the pci + tirofiban group compared with the pci group.At day 7 and day 30 post-pci, both groups displayed a time-dependent decline in the levels of c reactive protein (crp), tumor necrosis factor-α (tnf-α), interleukin-6 (il-6), and procalcitonin (pct) after pci ( p &lt; 0.05 ).Additionally, the patients in the pci + tirofiban group had lower levels of crp, tnf-α, il-6, and pct compared with those in the pci group at days 7 and 30 post-pci ( p &lt; 0.05 ).All patients in the pci + tirofiban and pci groups were followed up for 12 months by outpatient or telephone after discharge.There were fewer patients with lvef &lt; 50% in the pci + tirofiban group than the pci group ( p = 0.044 ).Furthermore, it was found that the incidence rate of major adverse cardiovascular events (maces) in the pci + tirofiban group was evidently lower than that in the pci group (12.90% vs.29.03%, p = 0.028 ).Taken together, our data suggest that additional administration of tirofiban could improve cardiac function and attenuate inflammatory response in stemi patients undergoing pci, which is worthy of promotion in clinic.

Journal: Evidence-Based Complementary and Alternative Medicine (2021)
Publication types: Clinical Study;
Implementing Critical Machine Learning (ML) Approaches for Generating Robust Discriminative Neuroimaging Representations Using Structural Equation Model (SEM)

Critical ml or cml is a critical approach development of the standard ml (sml) procedure.Conventional ml (ml) is being used in radiology departments where complex neuroimages are discriminated using ml technology.Radiologists and researchers found that sole decision by the ml algorithms is not accurate enough to implement the treatment procedure.Thus, an intelligent decision is required further by the radiologists after evaluating the ml outcomes.The current research is based on the critical ml, where radiologists’ critical thinking ability, iq (intelligence quotient), and experience in radiology have been examined to understand how these factors affect the accuracy of neuroimaging discrimination.A primary quantitative survey has been carried out, and the data were analysed in ibm spss.The results showed that experience in works has a positive impact on neuroimaging discrimination accuracy.Iq and trained ml are also responsible for improving the accuracy as well.Thus, radiologists with more experience in that field are able to improve the discriminative and diagnostic capability of cml.

Journal: Computational and Mathematical Methods in Medicine (2022)
Publication types: Research Article;
Impact of Small Incision Reduction and Suture Linked with Functional Appliance of Sufferers with Irrecoverable TMJ Anterior Disc Displacement

And aim.Irrecoverable anterior disc displacement (add) of temporomandibular joint (tmj) seriously affects the quality of life of patients.This research was aimed to explore the recovery effect of small incision reduction and suture on patients.Methods.90 patients with irreducible add of tmj treated from august 2020 to august 2021 were acquired in our hospital.They were randomly divided into control group and trial group randomly.There were 45 patients in each group.The sufferers in the control group were treated with oral drug therapy and small incision reduction and suture, while those in the trial group were treated with small incision reduction and suture linked with functional appliance.The pain score, dysfunction, joint function recovery, facial improvement, and clinical impacts of the two groups were contrasted.Results.Compared with that in the control group at 1 week, 4 weeks, and 6 months after therapy, the pain score in the trial group was markedly higher.After therapy, in the two groups, maximum vertical opening (mvo), left lateral excursion (lle), and right lateral excursion (rle) levels were markedly higher than those in the control group.The mri score of the trial group was markedly higher than that of the control group at 1 week, 4 weeks, and 6 months after therapy, and the total effective rate of the trial group was markedly higher than that of the control group.Conclusion.The use of small incision reduction and suture linked with functional appliance in the therapy of sufferers with irreducible add of tmj is beneficial to relieve pain, promote the recovery of body function, and contribute to the recovery of joint function.

Journal: Computational and Mathematical Methods in Medicine (2022)
Publication types: Clinical Study;
Image Processing and Machine Learning-Based Classification and Detection of Liver Tumor

The liver is in charge of a plethora of tasks that are critical to healthy health.One of these roles is the conversion of food into protein and bile, which are both needed for digestion.Inhaled and possibly harmful chemicals are flushed from the body.It destroys numerous nutrients acquired through the gastrointestinal system and limits the release of cholesterol by utilizing vitamins, carbohydrates, and minerals stored in the liver.The body’s tissues are made up of tiny structures known as cells.Cells proliferate and divide in order to create new ones in the normal sequence of events.When an old or damaged cell has to be replaced, a new cell must be synthesized.In other circumstances, the procedure is a total and utter failure.If the tissues of dead or damaged cells that have been cleared from the body are not removed, they may give birth to nodules and tumors.The liver can produce two types of tumors: benign and malignant.Malignant tumors are more dangerous to one’s health than benign tumors.This article presents a technique for the classification and identification of liver cancers that is based on image processing and machine learning.The approach may be found here.During the preprocessing stage of picture creation, the fuzzy histogram equalization method is applied in order to bring about a reduction in image noise.After that, the photographs are divided into many parts in order to zero down on the area of interest.For this particular classification task, the rbf‐svm approach, the ann method, and the random forest method are all applied.

Journal: BioMed Research International (2022)
Publication types: Research Article;