syedzayyan/paper_mill_benchmark huggingface dataset:
Computer-Aided Diagnosis of Children with Cerebral Palsy under Deep Learning Convolutional Neural Network Image Segmentation Model Combined with Three-Dimensional Cranial Magnetic Resonance Imaging

In this paper, we analyzed the application value and effect of deep learn-based image segmentation model of convolutional neural network (cnn) algorithm combined with 3d brain magnetic resonance imaging (mri) in diagnosis of cerebral palsy in children.3d brain model was segmented based on cnn algorithm to obtain the segmented mri images of brain tissue, and the validity was verified.Then, 70 children with cerebral palsy were rolled into the observation group (n = 35), which received mri for diagnosis after segmentation of brain tissue, and control group (n = 35), which were diagnosed by computed tomography (ct).The diagnosis results of the two groups were compared.The validity experiment verified that the image segmentation method based on cnn algorithm can obtain effective style graphics.In clinical trials, the diagnostic accuracy of 88.6% in the observation group was evidently superior to that of 80% in the control group ( p &lt; 0.05 ).In the observation group, one patient was diagnosed as normal, four patients had white matter lesions, 17 patients had corpus callosum lesions, and five patients had basal ganglia softening foci.In the control group, two patients were diagnosed as normal, two patients had white matter lesions, 19 patients had corpus callosum lesions, and four patients had basal ganglia softening foci.No notable difference was found between the two groups ( p &gt; 0.05 ).According to the research results, in the diagnosis of cerebral palsy in children, the image segmentation of brain 3d model based on cnn to obtain the mri image of segmented brain tissue can effectively improve the detection accuracy.Moreover, the specific symptoms can be diagnosed clearly.It can provide the corresponding diagnostic basis for clinical diagnosis and treatment and was worthy of clinical promotion.

Journal: Journal of Healthcare Engineering (2021)
Publication types: Research Article;
Comparison of Modified Above-Knee and Conventional Surgery with the Stripping of the Great Saphenous Vein of Varicose Veins of the Lower Extremities: A Retrospective Study

To compare the clinical effects of modified above-knee and conventional surgery with the stripping of the great saphenous vein of varicose veins of the lower extremities.Methods.Clinical data of patients with a varicose vein of the lower extremity from may 2016 to may 2018 were collected.A retrospective study was conducted on the patients receiving modified above-knee and conventional surgery with the great saphenous vein stripping.The baseline characteristics and long-term follow-up data were compared between the groups.Results.There were no significant differences in baseline characteristics between the two groups ( p &gt; 0.05 ).The surgeries were successfully performed by the same group of surgeons under local anesthesia and neuraxial anesthesia.The hospital stay, operation time, intraoperative blood loss, total length, and number of incisions in the above-knee group were comparable to those in the conventional surgery group ( p &gt; 0.05 ).The incidence of saphenous nerve injury and subcutaneous hematoma in the above-knee group was lower than that in the conventional surgery group ( p &lt; 0.05 ).There were no significant differences in recurrent varicose vein incidences ( p &gt; 0.05 ).After surgery, the venous clinical severity score (vcss) and chronic venous insufficiency questionnaire (civiq-14) scores of both groups were higher than those before operation ( p &lt; 0.05 ).There was no significant difference in vcss score or civiq-14 scores between the two groups postoperation ( p &gt; 0.05 ).At 24 months after surgery, the above-knee group (71.8%) and conventional surgery group (73.2%) resulted in changes of at least two ceap-c clinical classes lower than baseline, respectively.Conclusion.The modified above-knee technique can ensure clinical outcomes, reduce intraoperative blood loss and complication incidences, and shorten the operative time.This gives evidence that the modified above-knee technique is worthy of clinical application.

Journal: Computational and Mathematical Methods in Medicine (2022)
Publication types: Research Article;
Comparison of Efficacy and Psychology of Breast-Conserving Surgery and Modified Radical Mastectomy on Patients with Early Breast Cancer under Graded Nursing

To compare the efficacy and psychology of breast-conserving surgery and modified radical mastectomy in patients with early breast cancer (bc) under graded nursing.Methods.Forty-one early breast-conserving surgery bc patients admitted to our hospital from april 2020 to march 2022 were regarded as group a, and 52 with modified radical surgery were seen as group b.The operating time, intraoperative bleeding, postoperative drainage, and hospital stay were compared, and the postoperative adverse effects were counted.In addition, patients’ psychology and quality of life were assessed using the hamd, hama, and qlsbc rating scales.At the time of discharge, a treatment satisfaction survey was conducted.Results.The operative time, intraoperative bleeding, postoperative drainage, and hospital stay of patients in group a were lower than those in group b ( p &lt; 0.05 ).After treatment, the hamd and hama scores were lower in group a than in group b, while the qlsbc scores and treatment satisfaction were higher ( p &lt; 0.05 ).Conclusion.Breast-conserving surgery under graded nursing is less damaging to early bc patients.It can effectively shorten the postoperative recovery process and improve the psychology and quality of life, so it has higher clinical applicability.

Journal: Computational and Mathematical Methods in Medicine (2022)
Publication types: Clinical Study;
Comparative Efficacy of Water and Conventional Delivery during Labour: A Systematic Review and Meta-Analysis

In many maternal settings, water delivery is widely available for women who do not have an increased risk of complications during childbirth.Soaking in water during labor has been associated with a number of maternal benefits.However, the situation of water birth is not well known, there is lack of hard evidence on safety, and little is known about the characteristics of women who give birth in water.In this paper, we have explored the effects of water delivery compared to the conventional delivery on the health of mothers and babies.For this purpose, clinical trials were conducted including women in labor, in which participants were treated with water labor or conventional labor, respectively, in the experimental and control group.In this analysis, we have selected 17 eligible studies which included 175654 participants.Compared to the conventional birth group, the risk of apgar score &lt;7 at 5 min of age in the water birth group dropped by 28% (or = 0.72, 95% ci: 0.52–1.00, i2 = 25%, p = 0.05 ).Also, the duration of labor was shorter the in water birth group whatever the labor stage was.The patients who underwent water birth showed an obviously lower rate of neonatal intensive care unit (nicu) admission (or = 0.58, 95% ci: 0.39–0.86, i2 = 53%, p = 0.007 ).In this meta-analysis, it was seen that water delivery has clinical significance in alleviating the pain of mothers, promoting the safety of mothers and infants, and reducing postpartum complications.

Journal: Journal of Healthcare Engineering (2022)
Publication types: Meta-Analysis;
Comparative Analysis of the Anesthesia Effect of Cisatracurium Besylate and Mivacurium Chloride Otolaryngology Surgery

The aim is to investigate and compare the anesthesia effect of cisatracurium besylate and mivacurium chloride otolaryngology surgery.Materials and methods.108 patients who underwent ent surgery under general anesthesia in our hospital from november 2021 to march 2022 were recruited for retrospective analysis, in which patients in the experimental group a were anesthetized with cisatracurium besylate and patients in the experimental group b were anesthetized with mivacurium, and the anesthetic effects and recovery of the two groups were compared and analyzed.Results.There was no significant difference in mean arterial pressure, heart rate, and pulse oximetry levels between the two groups at the six time points of admission, anesthesia induction, intubation, end of operation, recovery of consciousness, and extubation (all p &gt; 0.05 ).The train of four stimulation values at end of operation, recovery of consciousness, and extubation were significantly higher than those of the experimental group a (all p &gt; 0.05 ).The recovery time of self-consciousness, extubation time, and eye-opening time of the experimental group b were significantly shorter than those of the experimental group a, and the occurrence of agitation was significantly less than that of the experimental group a (all p &gt; 0.05 ).The total incidence of adverse conditions in the experimental group b was significantly lower than that in the experimental group a ( p &gt; 0.05 ).Conclusion.Compared with cisatracurium besylate in otolaryngology surgery, mivacurium chloride anesthesia offers a promising route with respect to less impact on hemodynamics, faster postoperative recovery, absence of the accumulation of neuromuscular blockade, less adverse reactions, and higher safety.

Journal: Evidence-Based Complementary and Alternative Medicine (2022)
Publication types: Clinical Study;
Comparative Analysis of Machine Learning Methods for Breast Cancer Classification in Genetic Sequences

Breast cancer is the leading cancer in women, which accounts for millions of deaths worldwide.Early and accurate detection, prognosis, cure, and prevention of breast cancer is a major challenge to society.Hence, a precise and reliable system is vital for the classification of cancerous sequences.Machine learning classifiers contribute much to the process of early prediction and diagnosis of cancer.In this paper, a comparative study of four machine learning classifiers such as random forest, decision tree, ada boost, and gradient boosting is implemented for the classification of a benign and malignant tumor.To derive the most efficient machine learning model, ncbi datasets are utilized.Performance evaluation is conducted, and all four classifiers are compared based on the results.The aim of the work is to derive the most efficient machine‐learning model for the diagnosis of breast cancer.It was observed that gradient boosting outperformed all other models and achieved a classification accuracy of 95.82%.

Journal: Journal of Environmental and Public Health (2022)
Publication types: Research Article;
Cohort Study Summary of the Effects of Carboprost Tromethamine Combined with Oxytocin on Infant Outcome, Postpartum Hemorrhage and Uterine Involution of Parturients Undergoing Cesarean Section

Carboprost tromethamine injection has a high safety factor in clinical application and has a good effect on uterine smooth muscle and vasoconstriction.Carboprost aminobutyriol combined with oxytocin may be beneficial to infant outcome and uterine involution after cesarean section.Objective.To investigate the effects of carboprost tromethamine combined with oxytocin on infant outcome, postpartum hemorrhage, and uterine involution in parturients undergoing cesarean section.Methods.A total of 120 parturients undergone cesarean section in our hospital from february 2019 to april 2021 were selected as the object of study.The parturients were randomly divided into control group ( n = 60 ) and research group ( n = 60 ).The control group was treated with oxytocin, and the research group was treated with carboprost aminobutyriol combined with oxytocin.The amount of maternal bleeding, uterine floor decline index, the end of lochia, poor rate of uterine involution, infant outcome, and the incidence of adverse drug reactions were compared between the two groups.Results.The amount of bleeding in the research group was significantly lower than that in the control group ( p &lt; 0.05 ).The position of the last uterine floor and the index of uterine floor downward movement in the research group were significantly higher than those in the control group ( p &lt; 0.05 ).The disappearance time of bloody lochia and serous lochia in the research group was significantly shorter than that in the control group ( p &lt; 0.05 ).The end time of lochia in the research group was higher than that in the control group, and the rate of uterine involution in the research group was lower than that in the control group ( p &lt; 0.05 ).The neonatal weight and apgar score in the research group were higher than those in the control group, and the hospitalization rate of neonatal icu in the research group was significantly lower than that in the control group.The incidence of adverse reactions in the research group was significantly lower than that in the control group ( p &lt; 0.05 ).Conclusion.Carboprost aminobutyriol combined with carbestatin can effectively prevent the occurrence of bleeding after cesarean section, improve uterine involution, and improve neonatal birth quality, which is worth popularizing.

Journal: Computational and Mathematical Methods in Medicine (2022)
Publication types: Clinical Study;
Cognitive Function and Vitamin D Status in the Chinese Hemodialysis Patients

Vitamin d insufficiency and the cognitive function decline are both common in patients receiving hemodialysis (hd).The present study evaluated the relation between cognitive function and circulating vitamin d levels in hd patients in wannan medical college affiliated yijishan hospital, china.Methods.This study was conducted in 80 patients receiving hd in wannan medical college affiliated yijishan hospital.To measure cognitive function, montreal cognitive assessment-basic (mo ca-b) chinese version was used.The 25-hydroxyvitamin d [25(oh)d], which is applied to assess vitamin d status, was tested.One-way anova, tukey post hoc test, and the correlation and regression analysis were used in this study.Results.Based on the mo ca-b, cognitive function decline (the scores below 26) was present in 28 hd patients, accounting for 35% (28/80).The mean age of these patients is 50.5 ± 10.9 years old.The mean level of 25(oh)d was 16.1 ± 7.3 ng / ml in 80 hd patients.In univariate analysis, there was a significant relationship between mo ca-b score and serum 25(oh)d level ( p &lt; 0.05 ).The level of 25(oh)d was positively correlated with mo ca-b score ( r = 0.312 , p = 0.023 ), and the association was independent of demographic and clinical features.Conclusions.Vitamin d insufficiency may contribute to cognitive function decline in hd patients.Serum level of 25(oh)d is an independent protective factor of cognitive function in the hd patients.

Journal: Computational and Mathematical Methods in Medicine (2022)
Publication types: Research Article;
COG133 Attenuates the Early Brain Injury Induced by Blood-Brain Barrier Disruption in Experimental Subarachnoid Hemorrhage

Subarachnoid hemorrhage (sah) is a kind of severe hemorrhagic stroke, and early brain injury acted as one of the main causes of death and delayed neurological deficit in patients with subarachnoid hemorrhage.In this process, the function and structural integrity of the blood-brain barrier play an important role.In this study, we have observed whether the apolipoprotein e (apo e) mimetic peptide, cog133, can alleviate early brain injury after subarachnoid hemorrhage.For this purpose, an experimental subarachnoid hemorrhage model was constructed in mice and treated by intravenous injection of cog133 at a dosage of 1 mg/kg.Then, the function and integrity of the blood-brain barrier were detected, and the pyroptosis level of the neuron was determined.The results showed that cog133 could protect blood-brain barrier function and structure integrity, reduce early brain injury, and ameliorate neurological function after subarachnoid hemorrhage.In terms of molecular mechanism, cog133 inhibits blood-brain barrier destruction through the proinflammatory cyp a-nf-κb-mmp9 pathway and reduces neuronal pyroptosis by inhibiting nlrp3 inflammasome activation.In conclusion, this study demonstrated that apo e-mimetic peptide, cog133, can play a neuroprotective role by protecting blood-brain barrier function and inhibiting brain cell pyroptosis to reduce early brain injury after subarachnoid hemorrhage.

Journal: Journal of Healthcare Engineering (2022)
Publication types: Research Article;
Clinical Value of Contrast-Enhanced Ultrasound in Breast Cancer Diagnosis

Breast cancer (bc) ranks first in morbidity and mortality among female malignant tumors worldwide.This study is aimed at clarifying clinical value of contrast-enhanced ultrasound (ceus) in the diagnosis and differentiation of bc.A total of 108 bc patients admitted to our hospital from january 2019 to december 2021 were enrolled.All patients underwent conventional color doppler ultrasound and ceus imaging examination.All ultrasound images were analyzed by a senior (5+ years) sonographer.The lesion location, echo, size, and color doppler flow imaging (cdfi) blood flow distribution of benign and malignant bc were assessed.The transverse and longitudinal diameters of malignant bc presented significant elevation compared with the control group ( p &lt; 0.05 ).Ceus is more reliable than conventional ultrasound in the differentiation of benign and malignant breast lesions, and ceus has the best reliability.The comparison of ceus observation indicators between benign and malignant groups demonstrated that ceus enhancement patterns (time and intensity) and morphological features (lesion boundary, shape, range, homogeneity, and filling defect) presented statistical significance ( p &lt; 0.01 ).Irregular shape and range expansion were high-specificity indicators (all &gt;90.00%); fast-forward, high enhancement, clear boundary, and range expansion were high-sensitivity (all &gt;90.00%); and fast-forward, high enhancement, and clear boundary were low-specificity indicators (all &lt;50.00%); moderate sensitivity is as follows: homogeneous enhancement and range expansion (all &gt;80.00%).The area under curve of ceus ( 0.735 ± 0.053 ) presented elevation relative to conventional ultrasound ( 0.901 ± 0.024 ), with statistical significance ( z 1 = 2.462 , p &lt; 0.05 ).Relative to conventional ultrasound, the specificity and positive predictive value of ceus presented elevation ( p &lt; 0.05 ).In conclusion, in the differentiation of benign and malignant breast lesions, ceus has better diagnostic accuracy and reliability than conventional ultrasound.The diagnostic advantages of ceus are to elevate the diagnostic specificity and positive predictive value and reduce the misdiagnosis rate.

Journal: Computational and Mathematical Methods in Medicine (2022)
Publication types: Clinical Study;
Clinical Treatment and Prognostic Analysis of Patients with Aneurysmal Subarachnoid Hemorrhage

Subarachnoid hemorrhage (sah) is a serious disease caused by blood flow into the subarachnoid space due to rupture of blood vessels.All diseases that cause intracranial hemorrhage are the cause of subarachnoid hemorrhage.Among them, due to the particularity of intracranial blood vessels, intracranial blood vessels are more prone to aneurysms than other parts.Therefore, the incidence of aneurysmal subarachnoid hemorrhage (a sah) is extremely high.The purpose of this article is to study the clinical treatment and prognosis analysis of a sah patients.This article first summarizes the current status of sah research at home and abroad and summarizes its potential value and significance.On this basis, an in-depth study of the clinical treatment of a sah patients has been carried out.The physiological mechanism and clinical general differences of a sah were studied and analyzed.This article systematically describes the application of ctp in the treatment and prognosis analysis of a sah patients.Then, it will use a comparative analysis method, interdisciplinary method, and other research forms to carry out experimental research on the theme of this article.Research shows that rebleeding and blood sodium are the main factors for cerebral ischemia caused by a sah.

Journal: Journal of Healthcare Engineering (2021)
Publication types: Research Article;
Clinical Study of Progesterone Combined with Vitamin B6 in the Treatment of Amenorrhea Endocrine Disorders Caused by Antipsychotics

Endocrine disorders such as amenorrhea, lactation, and irregular menstruation caused by antipsychotics are common in female patients.How to reduce or eliminate these adverse reactions is a matter of concern.Objective.To evaluate the therapeutic effect of progesterone in combination with vitamin b6 in the treatment of antipsychotic-induced amenorrhea.Methods.In our hospital, from may 2019 to may 2021, 120 patients with amenorrhea caused by antipsychotics who underwent surgery were selected for this prospective study.The random residue grouping method divided them into a progesterone group (60 cases) and a vitamin b6 group (60 cases).Among them, the progesterone group was treated only with progesterone, while the vitamin b6 group was given progesterone in combination with vitamin b6.The differences in endocrine index, prolactin, uterine size, and endometrial thickness, effectiveness, and safety analysis of the progesterone and vitamin b6 groups of patients were observed and compared.Results.Before treatment, there was no change in the comparison of endocrine indexes between the progesterone and vitamin b6 groups ( p &gt; 0.05 ).After 1 month of treatment, there were significant differences in estradiol, prolactin, and follicle-stimulating hormone between the progesterone and vitamin b6 groups of patients ( p &lt; 0.05 ).After 1 month of treatment, there were significant differences in prolactin, uterine size, and endometrial thickness, and the vitamin b6 group was significantly lower than the progesterone group ( p &lt; 0.05 ).The clinical efficiency of 95.00% in the vitamin b6 group was significantly higher than 83.33% in the progesterone group ( p &lt; 0.05 ).There were no adverse reactions in the progesterone and vitamin b6 groups.Conclusion.The effectiveness of progesterone combined with vitamin b6 in treating amenorrhea caused by antipsychotics is significantly better than simple progesterone, which can effectively improve the endocrine condition of patients and provide a reference for the clinical treatment of amenorrhea caused by antipsychotics.

Journal: Computational and Mathematical Methods in Medicine (2022)
Publication types: Clinical Study;